text:
Wheelchair shocker: Viewers find accident video disturbing
Why couldn't a driver see a man in a wheelchair crossing in front of him? That's one question raised by the release of a dash cam video shot from the front of Albemarle County Police Officer Greg C. Davis' cruiser on November 5, the day he struck wheelchair pedestrian Gerry Mitchell in a West Main Street crosswalk.
The release of the video on Monday, January 7, also raises new questions about a December 12 memo that Charlottesville Police Chief Tim Longo wrote to address citizen concerns about his department's decision to ticket Mitchell.
The video, shot in broad daylight on a clear, sunny morning, shows with painful clarity the impact that sent the handicapped Charlottesville artist tumbling out of his chair to the pavement. And yet the Chief's memo, written six weeks after the incident, discounts witness accounts and attempts to deflect blame for the accident from the driver, an on-duty officer, and justify why Charlottesville police ticketed the man who'd been struck.
His investigating officer, Longo wrote, "discerned that the sudden nature of the pedestrian coming into the officer's field of vision prevented him from taking any steps (other than to immediately brake) to avoid hitting the pedestrian."
That explanation puzzles some who've now seen the video.
"That doesn't make sense to me unless he has zero peripheral vision," says pedestrian activist Kevin Cox. "If his peripheral vision is that limited, he shouldn't be driving."
Indeed, the video (posted at the readthehook.com), shows only a narrow view directly in front of the car, which was turning left onto West Main Street from Fourth Street by the Main Street Market. Mitchell was crossing the east side of the intersection heading south when he was struck.
The officer was not charged, and Longo maintains the collision was "unavoidable."
"My view," Longo writes in an email a day after the video's release, "was, and is, that the situation appears to have occurred so suddenly, that there was nothing else the officer could have done at that point but apply his brakes."
The video also features an unexpected soundtrack– the Black Eyed Peas' hip-hop song "My Humps"– which becomes audible immediately following the impact.
According to Albemarle County Police Lt. John Teixeira, the audio portion of the recording triggers when the cruiser's emergency lights are activated. The lights also trigger the video to begin recording rather than simply streaming, as it does while the car is in standard driving mode. (Like a car-version of TiVo, the video recording captures up to 90 seconds prior to activation of the lights.)
Cox is concerned about the music– and its source.
"I'd like to know where the music was coming from," he says, speculating that perhaps Davis was adjusting a stereo or even an iPod as he made the turn and struck Mitchell. Teixeira says he doesn't know the source of the music, and in his memo, Longo writes "there was no known indication that Officer Davis was distracted in any way. I specifically asked whether the officer was on his cell phone or his computer." The answer to both questions, Longo wrote, was "no," and in his email he maintains there was no reason to think Davis' attention was anywhere but on the road.
This seems to contradict the report from an eye-witness to the accident who reported that immediately after the accident, the officer "said he had been 'looking down' as he turned."
Although using a cell phone and websurfing are verboten while driving, police policy does not prohibit officers from listening to music from the car stereo, says Teixeira.
"It should!" exclaims Cox. "They're supposed to be doing their jobs, not listening to music. That's a recreational activity."
Even considering the initial impact that sent Mitchell reeling, another upsetting portion of the video occurs as Davis and a witness hoist Mitchell back into his chair mere seconds after he's been struck.
"As a professional, the police officer should have known not to move him," says Cox. "It's shocking to me that he didn't stop the witness from moving him, and that he then went so far as to help move him."
Mitchell, whose bones are brittle from the medication he takes to control AIDS, was treated and released at UVA hospital the day of the accident, then rehospitalized the following day in renal failure. In mid-December, doctors diagnosed broken bones in his shoulder, something he believes happened when he was lifted from the street into his chair.
On New Year's Day, three days before a show of his paintings was scheduled to open at the Mudhouse coffee shop, Mitchell was hospitalized with swelling in his joints and in "deep pain," he says. He remained hospitalized at Hook press time Tuesday, but he was scheduled to be moved to an area nursing home where he will remain for a minimum of three weeks.
Watching himself being struck by the car was "very upsetting," says Mitchell, who adds that the video confirms for him that his recollection of the accident is correct. He says he hasn't determined what steps he'll take– or whether he'll file a civil suit against the county or the city.
"That hasn't been part of my mind," he says. "I've been focusing on trying to get well."
While it was an Albemarle County police officer who struck him, what happened after the accident added insult to his injuries. Charlottesville police, who investigated the accident, opted to ticket Mitchell, and delivered the summons while he was being treated in the UVA emergency room. Although the charge, failing to obey a pedestrian signal, was eventually dropped because the statute didn't exactly describe the pedestrian signal Mitchell supposedly violated, Charlottesville Commonwealth's Attorney Dave Chapman declined to apologize for prosecuting Mitchell.
Longo, however, says he saw Mitchell in City Hall several weeks ago, apologized to him, and says he plans to "follow up" now that the case is resolved.
Teixeira says the Albemarle County Police Department has learned a lesson from the incident– "to respond empathetically as soon as you can." Police policy prohibits officers from commenting on internal or external investigations, and Teixeira– who on Monday issued an apology to Mitchell on behalf of Albemarle County Police– believes the policy contributed to community concerns that the Department was engaging in a cover-up or simply didn't care.
"That's not the case," he says.
Albemarle County's internal investigation into the incident will wrap in a couple of weeks, says Teixeira, who doesn't know whether results will be made public. The video was released to the public two business days after the case was dropped and after numerous media appeals for the public document. Texeira says the release, which might legally have been withheld until the internal investigation wrapped, was an effort to help people understand how the accident happened.
"We're hoping by putting the video out," he says, "that people can make their own minds up."
16 comments
Sounds to me the police (Albemarle and Charlottesville) are GUILTY as charged! Sue them!
quote "Although using a cell phone and websurfing are verboten while driving, police policy does not prohibit officers from listening to music from the car stereo, says Teixeira."
In all my worldly travels verboten is German for forbidden or prohibited. So, I therefore have never heard anything so damn insulting to the public's intelligence in my entire life. I see Albemarle cops talking on their cell phones every day while driving on duty in marked and unmarked cars, trucks and SUVs. One such moron ran through a red light southbound at Sperry Marine at approximately 70 to 75 mph and almost hit me broadside one evening while talking on a cell phone. Had we made contact it most certainly would have kiled or maimed the person in the front passenger seat of my Cadillac. And had I been 1 to 1.5 seconds earlier entering the intersection we most certainly would have made violent and devastating contact. At the next red traffic light, hydraulic and Emmett, the cop couldn't get through heavy traffic and I could see he was still talking on his cell phone and royally dissed off because people weren't getting out of his way fast enough. It's just a matter of time before innocent civilians get killed by police cars driving crazy enroute to a call. 5 or 6 years ago a county cop in a white marked Caprice ran a stop sign and creamed a Toyota truck. The people in the truck were lucky they weren't killed or seriously maimed.
Well if anyone would bother to pay attention the female county PD sergeant who killed someone in her car, she'd wrecked multiple times before. I was there. Saw it with my own eyes and still have the pics on my PC to prove it. Jaws of life were involved once. I was not shocked at all to see what she did. She's been a danger for YEARS. They CLEARLY COVER FOR THEIR OWN!
I see a definite double standard here. How about a report that shows the frequency of PD driving incidents and accidents. This guy was distracted and is clearly at fault. I hope a judge gets to decide. Only then will the law enforcement in this town get out from under the mistaken impression they are above the laws they are supposed to enforce.
quote "Well if anyone would bother to pay attention the female county PD sergeant who killed someone in her car, she'd wrecked multiple times before. I was there. Saw it with my own eyes and still have the pics on my PC to prove it. Jaws of life were involved once. I was not shocked at all to see what she did. She's been a danger for YEARS."
I find that hard to believe. She locked the keys in her vehicle every 5 minutes and had to have another cop bring an extra set to her each time. :)
I've always been impressed by Longo, but this case is disturbing. I can't imagine watching that video and thinking that the officer did nothing wrong. It is clear that he wasn't paying attention. How else do you run into a wheelchair that has nearly crossed the road you are turning on to? Mitchell gets hit from behind! This isn't a matter of peripheral vision. When you're turning left, you don't look straight ahead, you look left.
But I can understand an accident. People run into things and other people all the time. What is so disturbing is the fact that having this video the police charged Mitchell! This is insane!
Ohh brother, I can't believe it, here I go defending Longo again. Longo was out of the loop when the charges were placed. And it appears Longo was (white) lied to as he obtained information to prepare his memo to City Council. Supposedly Longo has apologized to Mitchell face to face as well. I think the ability and obligation to charge the county cop with reckless driving now lies with the city commonwealth attorney. Things like this can come home to haunt the commonwealth attorney at the next election. Just like Camblos bit the dust in November of 2007. Never in his wildest dreams did the Republican Camblos think he could lose the election in a Republican county.
Peripheral vision does play a vital role in this accident. Even if the county cop didn't look left physically by moving his head, he should have seen Mitchell with his peripheral vision. Unless he was looking down like he first admitted. And looking down while driving a car forwards was enough to justify charges being placed. But it was a cop ya know. Who's going to charge him at the scene when other cops work the accident? :)
Had Longo been the first cop on the scene I honestly believe he would have charged the county cop and let the courts sort it out. How many people would really care if disses off Chief Miller? Has Chief Miller apologized to Mr. Mitchell?
Chief Longo did meet face to face with Gerry. He told Gerry he wanted to be fair and he was congenial, nice, and friendly, as he always is. He did not apologize.
Personally,I don't know that Longo is really the one who should be apologizing. Grissom wrote the ticket and Davis hit him. The most important apology is the one that should come from Davis.
I don't think the county will ever apologize directly to Gerry unless ordered to do so by a judge.
any one of us could have run into poor Mr. Mitchell. I think we should settle that as truly an unfortunate accident. The part that is undisputably NOT an accident is how the situation was handled AFTER the collision. If I were chief longo and my underlings had put my ass out the window like his underlings did to him I would have fired people by now. Very publicly.
The Chief of Police has a different job than all of the other people in the department. His job is truly to be an advocate for the Citizens, The rank and file officers, all the while enforcing the laws as prescribed by the eleted officials.
He needs to be respected by EVERYBODY ALL THE TIME. Nobody has to like him, but he needs to havethe earned respect of all. That is the only way that the department can function.
Kevin, my bad! I thought I read somewhere where Longo had apologized.
Radar, it wasn't an accident. It was negligence. Any person who can't see something as big as a man in a wheelchair has no business operating a 4,500+ pound motor vehicle on the public highways. When a child runs into the street chasing a ball and gets hit by a car... that's an accident. Maybe once the city police get their newfangled black and white patrol cars on the road soon, people can see them more clearly and stay out of crosswalks when they are approaching? (I crack myself up sometimes!)
rambo hater..
I respectfully disagree. While I believe the officer must have been looking down or strait ahead, I still think that it unfortunately could have happened to any of us. I would hope that if it happened to me and I explained to the judge that
1) I was looking ahead for oncoming traffic and did not turn in time to see him and that..
2) I immediately helped and apologised to Mr Mitchell.
3) That I reported it to my insurance company as 100% my fault.
4) I followed up with mr. Mitchell's condition and progress.
5) I stated for the record that I am now twice to ten times as careful as I was in the past..
... that maybe the judge would go easy on me and let me off with a reduced charge....
The problems with accountability started AFTER the collision...
Well, first off, you call me rambo hater. Which is fine. Then you basically explain why I am a rambo hater, you list everything they refuse to do whenever they are at fault in a critical incident. So you should be a rambo hater too in my opinion. Or at least a rambo disliker.
Is disliker a word? :)
Rambo hater...
I do not hate the Police or what they are supposed to stand for. What I do hate is the lack of accountability which stems from a lack of the balls that it takes to keep the department above reproach. The officers have become arrogant because the public has no confidence in them because when a few officers were A-holes the other officers looked the other way. It is up to chief Longo to FIX THIS PROBLEM. If heads need to roll then let em roll.
I want to trust the Police but ANYONE would be a fool to trust them in light of this event and the one on water Street where the cop lost his temper because someone told him to slow the F down.
Why is it that we always hear the "horror" stories about police and what they do/don't do? It is sad that in our society, we let the actions and mistakes of some ( yes, they are held to a higher standard but still make mistakes ) decide how we feel about the whole. Remove them, take away the few officers the county has off the street, the including the street that the unfortunate accident occurred, and then see how appalled you are. You could not pay me enough to be an officer these days and I think the officers are beginning to feel the same way. The county is already very short handed ( about 10 officers per shift for the entire county according to several sources ). We are sad when they get killed because they are forced to consider law suits in times where split second decisions need to be made, yet we continue to persecute.
I challenge the media to actually begin to seek out more of the positive contributions law-enforcement makes ( in addition to mistakes which are, too ,news worthy ). It would certainly be the fair thing to do.
I think the officer should be charged with something.I agree something must be wrong with his peripheral vision if he couldn't see Mr Mitchell in a wheelchair in the crosswalk and had almost completely crossed the road. I am just sorry he had to go through all he has.That's the problem now when it comes to an officer in the wrong or needs to be held accountable for wrong where does justice come in for innocent civilians?That could have been anyone a man,woman,woman and child. All I can say is before crossing make sure there are no oncoming officers you may be next.
Correct, CC! Had it been a normal person walking it might have been much worse. They might have been knocked down and run over by the cop car. The only thing that saved Mr. Mitchell was the wheelchair absorbing the initial impact and PUSHING him out of the way.
I am a motorist mostly, I don't use crosswalks very often. My biggest concern is a police car running a red light and hitting my vehicle. Not only was I almost taken out by a reckless county police car myself a few years ago, I also witnessed a Ranger pickup truck almost being creamed by a county cop in front of Martha Jefferson Hospital a few months ago. They still think people can see and hear them for some reason. The nerve of people, riding around with the windows up, air conditioning on and the radio cranked up! I've said it once before, I will say it again.... it's just a matter of time before some rookie in a police car kills somebody in the Charlottesville and Albemarle area.
Its hard enough to cross a street in a croos walk, but when a police officer hits you what do you do? Is it just me but aren't police officers supposed to be helping individuals safely maneuver across cross walks anyway? I have no idea what this police officer was thinking. He should be FIRED, he hit a man, probably changing a radio or simply not paying attention, and then had the Audacity to serve a ticket, knowing Mr. Mitchell had be injured. What if this had been a small child and not a grown man in a wheel chair, I wonder how Albermarle county and Charlottesville would have responded then. I say SUE SUE SUE!


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subset: commoncrawl


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This month in Allure, a writer describes how being incarcerated taught her some life lessons — about the importance of makeup! Meanwhile, the editors explain the key to looking good naked is to lose weight and get more beauty treatments.
In "Beauty Behind Bars," Piper Kerman writes,
No one who meets me would ever think that I once resided behind bars. I am a Seven Sisters-educated, middle-class, professional woman with a loving family and a solid work history.
What? Middle-class ladies don't go to jail! Ever! She explains,
But a brief and reckless involvement with the narcotics trade in my early 20s came back to haunt me years later (because, believe me, there is no escaping the consequences of one's actions), and I was sentenced to federal prison for a ten-year-old crime.
Totally understandable — so many of my fellow Seven Sisters-alumnae weren't sure what to do after graduation and wound up falling into the narcotics trade themselves. It happens.
We never learn if Kerman is sorry for her crime, but she does tell an interesting story about why makeup is important to female prisoners. She learns there are some drug store cosmetics available at the prison commissary, including, "liquid eyeliner, Maybelline foundation, and Great Lash mascara." (Don't expect Maybelline to start using the phrase, "#1 Convict-Recommended Brand" on their packaging.) At first she finds, "that when I was dressed in shapeless men's clothing and steel-toed shoes, some mascara and lip gloss went a long way toward making me feel like perhaps I still had something to offer my fiance," but by the end she bonds with the other ladies through pedicures and doing each other's hair. Does she learn something about the perils of dabbling in drug trafficking? It's unclear, but she does discover that beauty products (Allure's raison d'être) are important for maintaining you individuality and bonding with other ladies. (So pack some mascara for your next prison stint.)
Also: This is Allure's annual naked lady issue, but even when stripped-down, Kara DioGuardi, Emmanuelle Chriqui, Jessica Capshaw, Colbie Caillat, and Regina Hall aren't terribly interesting. Catherine Zeta-Jones poses sans-clothing too, but she isn't really nude if you count the figure-obscuring light bursts and retouching that cover her entire body.
Since we common folk don't have the benefit of a professional Photoshopper, the editors offers a list of "22 Way To Look Better Naked." The subhead reads, "Summer — and life, for that matter — is too short to waste hating your body and scrutinizing every pucker and pore." So true! Too bad all of the tips involve constantly rubbing creams on yourself to fade scars, reduce cellulite, and minimize stretch marks, and getting pricey cosmetic procedures to remove hair and spider veins. Most of which seem pretty time-consuming anyhow.
(Click to enlarge.)


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Heather and grass burning: rules and applying for a licence
When you can burn, when you need a licence and how to burn safely.
You can burn heather, rough grass, gorse, bracken and Vaccinium species (such as bilberries) if you follow the rules below and get a licence where required.
If you do not follow the rules for burning grass or heather you can be prosecuted and fined up to £1,000.
Burning safely
When burning heather or grass you must:
- start burning between sunrise and sunset
- have enough people and equipment to control the burn
- take all reasonable precautions to prevent injuring people and damage to land and property
- not cause injury, interruption or danger to road users
- not create smoke likely to damage health or cause a nuisance
- not disturb or destroy wild birds and their nests, or other protected animals, plants and habitats
- not damage important monuments
- not pollute watercourses and groundwater, for example, through soil erosion caused by burning
Further advice on burning heather and grass is provided by the Uplands Management Group
Burning season dates
You must burn during the 'burning season', which runs from:
- 1 October to 15 April in upland areas (severely disadvantaged areas) - find these on MAGIC
- 1 November to 31 March in other areas
When you need a licence
You need a licence if you want to:
- burn outside the burning season
- burn more than 10 hectares in a single burn
- burn more than 0.5 hectares on a slope steeper than 45 degrees or on rocky or scree areas
- burn in a way that exposes more than 0.5 hectares of bare soil (where no more than 2% is covered by plant material)
- burn in a way that exposes bare soil that stretches for more than 25 metres along the banks of a watercourse (any channel with flowing water apart from pipes) and is more than 1 metre wide throughout
- leave soil smouldering for more than 48 hours
You also need consent from Natural England to burn in environmentally protected areas, for example a site of special scientific interest.
When you don't need a licence
You don't need a licence to burn heather and grass on:
- private gardens
- allotments
Licences are free.
You need to apply to Natural England for a:
- – Natural England can only grant a licence if the burning is necessary to conserve, enhance or manage the natural environment, or for safety
- – Natural England will only grant a licence if the burning is needed to maintain the land or for pest control
When to apply
You need to apply:
- 28 to 56 days before the burn (if you're burning outside the burning season)
- at least 28 days before the burn and after the previous burning season (if burning in the burning season)
If you don't follow the rules you can be prosecuted or Natural England may:
- send a warning letter
- give you a caution
- serve you with an injunction
- issue a 'burning notice' requiring you to notify Natural England of any proposed burning of permitted vegetation for up to 2 years
You can appeal against a burning notice within 28 days.
Farm subsidy payments
Farmers need to follow Good Agricultural and Environmental Condition (GAEC) rules on heather and grass burning to qualify for a full farm subsidy payment. See GAEC6 for rules on heather and grass burning.
Natural England
Environmental impact assessment helpline
Email: email@example.com
Telephone: 0800 028 2140


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I've been admittedly dragging my feet putting this video together, and it took me awhile to figure out why. But as I was lying in bed this morning, going "Beru, get your Staghelm video done today!" I realized that the reason I've been slow with it is simply because there just isn't much to heal in this encounter! There is less about healing in this particular guide than in my others, but there are still a few druids related tips that I offered.
(please note that this video will be best viewed in one of its higher resolutions)
A few notes!
- The Healers – We use 5 healers, because our healers help to soak orbs because of our melee heavy roster. A lot of guilds will use only 4 healers (one in each quadrant), and have their healers keep legendary concentration through the orb phase to assist with the healing. Ultimately, you will have to decide what works best for your raid team and build your strategy.
- The Tank – This is a one tank encounter. Not much changes for the tank between heroic and normal, so they should be able to easily translate things like cooldown usage easily into heroic.
- Tranquility – I actually break one of my rules here, and don't maximize my tranquility. Really, outside of the orb phases there isn't much use for it. I do try to use it in both orb phases, however in this particular pull where I have the clumped up orb, I just don't have the time to stop to cast with the constant rotation. When there is just one orb up, it's very easy to communicate to my soaker partner that he needs to move because I'm tranqing. When push comes to shove, use it when you feel it's best and will give the best benefit to the raid.
- Barkskin, Baby! – There are a lot of optimal times in this encounter for Barkskin. Orb soaking, searing seeds, cat leaps. Don't hesitate to utilize it when you are going to be taking damage! It's a very short cooldown, and can help save your life, or at least make it easier.
- Telegraphing Cat Leaps – I mentioned in the video that as the fight goes on, those cat leaps become more potent. To the point that if you aren't already moving when he lands, you are likely going to die. The best way to do this is pay close attention to his energy, when he hits 100 already be on the move if he's coming your direction. Don't wait for him to land before you take action or you will likely end up dead.
Version:4.21; InvertAuraBelow:10; buffname:Searing Seed; bufftype:2; texture:10; alpha:1; sound:25; y:171; timer.h:3.42; timer.enabled:true; timer.cents:false; timer.y:104


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Functor-Applicative-Monad Proposal
From HaskellWiki
Haskell calls a couple of historical accidents its own. While some of them, such as the "number classes" hierarchy, can be justified by pragmatism or lack of a strictly better suggestion, there is one thing that stands out as, well, not that: Applicative not being a superclass of Monad.
The topic has been discussed multiple times in the past (cf. link section at the bottom). This article was updated to describe the current, and very likely to succeed, Haskell 2014 Applicative => Monad proposal.
Pragmatic and short version
The following is a list of things you may have to change in your code so the AMP doesn't break it.
- Add Applicative/Functor instances for all your Monads. If you don't care about efficiency, you can simply derive these instances from the Monad by adding the following code:
-- Monad m
import Control.Monad (liftM, ap)
import Control.Applicative (Applicative(..))
instance Functor m where
fmap = liftM
instance Applicative m where
pure = return
(<*>) = ap
- Add an Alternative instance for all instances of MonadZero. This can again be done easily using
-- MonadZero m
import Control.Monad (mzero, mplus)
import Control.Applicative (Alternative(..))
instance Alternative m where
(<|>) = mplus
empty = mzero
- Change your API to not define functions named
Detailed description
Main text of the Haskell 2014 AMP
Mailing list discussion of the proposal
Previous proposals
- From early 2011: GHC ticket – Makes Applicative into a superclass of Monad, but does not deprecate any existing names
- See [1] for the associated discussion.
- The Other Prelude


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What Does the Most Good?
In the United States, improvements in basic infrastructure such as clean water, good sanitation practices and nutrition dramatically improved public health in the early part of the century. The widespread use of vaccines and introduction of antibiotics continued to lower the burden of infectious disease. Such improvements are necessary for social and economic development. Significant problems persist in many parts of the world.
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The Impact of Public Health
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I ordered a bottle by calling the Dior boutique in Vegas.
I ordered a bottle by contacting the Dior boutique in Vegas (there are two of them there).
Hey, where did you buy a bottle of Eau Noire? Because it doesn't exist on the internet apart from the perfumed court and eBay (which only sells 8oz bottles O.o)
Fantastic! Hope you enjoy them. Since we have similar tastes, please let me know if you discover anything that you'd think I'd like.
It appears we have similar tastes (smells, rather). I'll be assaulting your top 5 on perfumedcourt soon (other than New Haarlem and Chergui, which I already have)
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Our curriculum is a journey from Parent/Child classes through 12th Grade.
Early Childhood
The young child is held in reverence by loving teachers and parents and allowed to explore the beauty that surrounds them, planting the seeds of imagination, creativity, and confidence.
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Fun and creative extracurricular opportunities for our students throughout the school year.


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Arleen Cuklanz-Kussman
TERRIL – Funeral services for Arleen Cuklanz-Kussman, 88, of Clarkfield, Minn. were held 1:30 p.m. Wednesday, Oct. 23, 2013, at Immanuel Lutheran Church in Terril. Interment was at Fairview Cemetery in Terril.
She died Saturday, Oct. 19, 2013, at Clarkfield Care Center in Clarkfield.
Henry-Olson Funeral Home of Estherville is in charge of arrangements.


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text:
Ford said today it earned a profit of $2.7 billion in 2009, a stunning improvement over its historic, $14.7 billion loss in 2008. It's the company's first full-year profit since 2005. But, they're not out of the woods yet.
Don't get us wrong, it's an impressive number, especially for a year that saw industry sales drop to their lowest level since 1982. But it's also not entirely indicative of the financial health of the company. The year-end results were buoyed by a $4.7 billion one-time gain the company booked in the second quarter after recapitalizing a chunk of its debt, and benefited from a total of $2.6 billion in other special items for the year.
Ford's also still losing almost $1.5 billion from the automotive side of the business — which means they'll still need to make cuts if they'll want to survive even given an assumption of U.S. auto industry sales predicted at 11.5-12.5 million vehicles.
But, Ford is predicting that's what they'll do as the company said it now expects to be profitable for full year 2010 on a pre-tax basis excluding special items, for North America, total automotive and total company, with positive automotive operating-related cash flow.
We're just wondering how they'll do that given cutting further into some departments — say, engineering and product R&D — to achieve those savings will definitely hinder new product development. [via Ford]


text:
When dealing with women; I think the problem is; I have to become someone other then who I am to be with women! Im not myself. I have to become more worldly or socio-able! Im not good enough for where I want to be! I have to like myself more, or be more curious! I have to like myself more; who's fault is this; meaning, is it a women or mine! who has to do the work! I do, so I better just get started with it!
I have to be up to speed of who I want to meet; the quality of person! Im not socially up to speed! I still need someone to rescue me and see me through and take care of me. This is not what I want, altho I need it! so, a dilemma is occurring within me! I like what I see but don't bb go after it!
Much more practice in this area that I may get a better understanding !
I have to become more outgoing and less afraid!


text:
Using a combination of motion capture and a stunt-driven Toyota iQ, graphic designers have created a "Toyota iQ font," a slick and wholly unique approach to advertising the new micro-machine. Video of the process below.
iQ font - When driving becomes writing / Full making of from wireless on Vimeo.
The project was undertaken by ad-agency Happiness-Brussels and used a specially designed motion capture system and a be-dotted iQ with stunt driver Stef Van Campenhoudt at the helm to create the swooping font. It's apparently going to be available for free download, should you want another non-standard font to annoy your coworkers with, but at this time the primary download site doesn't appear to be working, though this one does. (Thanks Tanshanomi) [Fast Company]


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Tuesday, December 15, 2009
Wordless Wednesday - Christmas Decorations!!
19 comments:
- Terra HeckJanuary 25, 2010 at 8:18 PM
Nice decorations! Happy Holidays!ReplyDelete
Your decorations are lovely. Happy WW!ReplyDelete
- Piera-Jolly MomJanuary 25, 2010 at 8:19 PM
They are beautiful! I want to do some Christmas scenes too--maybe next year. Happy WW and Merry Christmas : )ReplyDelete
Lovely ornaments!ReplyDelete
They are beautiful! Happy WW.ReplyDelete
Love the advent calender! :) Thank you for hosting WW!ReplyDelete
Your decorations are all very cute! I always wished I had that type of advent calendar!ReplyDelete
Oh so cute! Love all of them. I need a count down for the kids, right now it is just them asking Mommy repeatedly how many days until Christmas.ReplyDelete
Lovely post.ReplyDelete
So pretty! That calendar is really sweet, and I love the snowman!ReplyDelete
Cute countdown. I want a lighted village someday...ReplyDelete
- Julie@MomspectiveJanuary 25, 2010 at 8:25 PM
Great Wordless Wednesday! Hope youre having a wonderful Holiday season!ReplyDelete
We have a very similar countdown calender that my mom made when me & my sins were little. I love that I get to use it with my kids now!ReplyDelete
You have such lovely decorations.. Each holiday you post pictures and I wish I had the same ones... You do need to pick up a few hawaiian ones now though.... We had some but the movers broke them.. grrrrr Mele Kalikimaka....ReplyDelete
those are lovely ornaments!ReplyDelete
Love the advent you have! That snowman is SO COOL!ReplyDelete
I love this time of year! Happy WW!ReplyDelete
Great decorations!ReplyDelete
- Lorie ShewbridgeJanuary 25, 2010 at 8:30 PM
That's a great countdown calendar... and I, too, love lighted villages. We have a ton, but no room for them right now. Then have been stored in their boxes for 5 years. We are saving money to have something built for them. I REALLY like that snowman... I love when decorations are animated. This is my favorite time of year. :-)ReplyDelete


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- Minireview
- Open Access
- Published:
From bending DNA to diabetes: the curious case of HMGA1
Journal of Biology volume 8, Article number: 64 (2009)
10k Accesses
8 Citations
3 Altmetric
Although mice lacking the architectural DNA binding factor HMGA1 are diabetic and express very low levels of the insulin receptor, they have increased insulin sensitivity. A study in BMC Biology now suggests that changes in circulating retinol binding protein partly account for this paradox.
The inexorable rise of pandemic diabetes mellitus is already leaving a devastating global trail of premature debility and mortality in its wake. Around 90% of patients with diabetes ('mellitus' will be assumed from here on) have type 2 diabetes (T2DM), which is intimately associated with and driven by increasing levels of obesity. However, despite intensive investigation in humans and model organisms, many aspects of its pathogenesis remain unclear, and there is an imperative need to refine understanding of the disease process in order to develop new and rational therapies.
Difficulty in elucidating the precise pathological basis of T2DM stems in part from its heterogeneity – indeed, the certainty implied by this apparently specific label, applied by default to most patients without collateral diagnostic features of other, better defined types of diabetes, may be illusory. It is true that most patients with T2DM do share certain general characteristics – they are mostly overweight or obese, mostly in middle age or beyond, and mostly have normal or elevated insulin at diagnosis – but extensive clinical observation suggests that the predominant physiological defect(s) commonly differs significantly among them. Such heterogeneity is not surprising a priori – intermediary metabolism is regulated in a complex manner by constant metabolic dialog among organs, including brain, liver, fat, pancreas and skeletal muscle. This is necessary to serve the sometimes competing organismal needs of growth, reproduction and day-to-day survival in the face of fluctuating nutritional and environmental inputs, but the number of 'moving parts' in this complex system also renders it susceptible to perturbation in many different ways. Chiefari et al. [1] now report in BMC Biology the latest installment of a fascinating – and sometimes perplexing – line of investigation that has been running for the past 20 years, centered on the DNA-binding protein HMGA1. The new findings not only give intriguing insights into metabolic crosstalk between tissues in vivo, but also illustrate several key themes and challenges in current T2DM research.
HMGA1 in human severe insulin resistance
The story began more than two decades ago with identification of a boy with high glucose levels despite extremely elevated insulin – that is, severe insulin resistance (IR) [2]. His blood cells showed very low insulin binding and insulin receptor expression, and yet, surprisingly, neither of the alleles of the gene encoding the insulin receptor, INSR, had any mutation [3]. Later independent studies found that the protein HMGA1 was bound to key sites in the promoter of the INSR gene, and provided evidence that HMGA1 is involved in the high levels of INSR expression in insulin-responsive tissues [4]. HMG (high mobility group) proteins are the second most abundant nuclear proteins after histones, and proteins in the HMGA subfamily, although without intrinsic transcriptional activating activity, function as permissive 'architectural' transcription factors, binding AT-rich sequence motifs, distorting DNA and nucleating assembly of complexes of other factors with canonical transactivation motifs [5]. These biochemical and clinical genetic lines of investigation converged in 2004 with the demonstration that the insulin-resistant proband, as well as three further patients with severe IR, had extremely low levels of HMGA1 expression, in all cases as a result of mutations or deletions severely reducing levels of HMGA1 mRNA [6].
This biomedical detective work was of direct importance to these patients with HMGA1 defects, but the question arises as to whether such 'boutique' examples of rare monogenic IR have any relevance to the common forms of IR and T2DM, which, although they show high heritability, are thought likely to be predisposed to by milder defects in several different genes. The most powerful genetic tool used to seek association between common genetic variation and disease is the genome-wide association study, but such studies have explained only a tiny proportion of the heritability of T2DM so far. Two possible interpretations of this are (i) that different types of rare genetic variation collectively have a more dominant role in T2DM susceptibility than common genetic variation, and/or (ii) many patients in the non-diabetic control group may be in the long prodromal phase of IR, which precedes pancreatic beta cell decompensation and hyperglycemia and is commonly asymptomatic, attenuating the power of genome-wide association studies to detect genetic differences between the groups. The relatively disappointing yield from population-wide genetics makes study of monogenic forms of IR or diabetes, in which the primary defect is known, and its comparison with common T2DM/IR, in which the primary defect is unclear, particularly valuable, as exemplified by humans with INSR defects [7]. Identification of such human 'experiments of nature' also serves to validate candidate genes for more detailed resequencing studies in wider populations.
HMGA1 in mice and humans
There are significant practical and ethical limitations to study of patients, however, and only four patients with HMGA1 mutations have been reported in total so far. Hmga1-/- mice were therefore generated for more detailed mechanistic study [6]. In keeping with the human phenotype, these animals showed a 90% reduction in insulin receptor expression and hyperglycemia after glucose challenge. In other respects, however, the phenotypes of mice and humans radically diverged: all affected humans had severe peripheral IR and corresponding hyperinsulinemia, whereas knockout mice were actually hypersensitive to insulin, with increased levels of expression of the insulin-responsive glucose transporter Glut4 in muscle and enhanced whole-body insulin-stimulated glucose disposal (Table 1). This is in effect the opposite phenotype to that in humans, and implies major differences in both insulin secretion and peripheral insulin action between the species. The earlier failure of insulin secretion in mice than humans suggests a failure of glucose-stimulated insulin secretion in individual pancreatic β cells and/or failure of proliferation of these cells. This may relate to a more important role for the Insr in this process in mice, as suggested by the progressive hyperglycemia of beta-cell-specific Insr knockout mice [8]. The difference in peripheral insulin sensitivity, suggesting the existence of a pathway in mice that can compensate for severe loss of Insr, was left unexplained, however.
HMGA1 and metabolic messengers
The contribution of the recent paper by Chiefari et al. [1] is to offer a partial explanation for this observation. The new work draws on growing appreciation that insulin-sensitive tissues communicate not only through substrate fluxes, but also by secreting factors that signal specifically to distant tissues. Adipose tissue, in particular, is now seen as a highly dynamic endocrine organ producing many so-called 'adipokines', including leptin, which has a thoroughly validated metabolic role, adiponectin, and many other factors with varying credentials as bona fide signaling molecules. One of the more recent of these is retinol binding protein (RBP), product of the Rbp4 gene in mice. Although mostly produced by the liver, RBP also comes from white adipose tissue, and its expression there is inversely related to Glut4 expression [9]. Furthermore, Rbp4-/- mice show enhanced insulin sensitivity, and providing RBP either exogenously or by overexpression induces IR [9].
Chiefari et al. [1] hypothesized that altered Rbp4 expression might explain the discordance between reduced Insr expression and enhanced insulin sensitivity in Hmga1-/- mice. The first key evidence that this may be partly true comes from the demonstration that these mice do have severely reduced levels of Rbp4 mRNA and circulating RBP. Furthermore, the enhanced expression of Glut4 in muscle of the knockout mice is normalized by exogenous RBP, and the enhanced glucose-lowering effect of insulin in the knockout animals is markedly attenuated by the same treatment (Figure 1). In wild-type mice glucagon strongly stimulates expression of Hmga1 and then Rbp4, an effect absent in Hmga1-/- mice. This suggests that Hmga1 is at least permissive for glucagon-induced stimulation of Rbp4 via a direct effect of Hmga1 on the Rbp4 promoter. Glucagon exerts cellular effects largely through the second messenger cAMP, and together with previous in vitro studies, this implicates cAMP as a proximal cellular regulator of both genes. However, exactly how RBP impairs insulin signaling is unclear: insulin-stimulated phosphorylation of phosphatidylinositol 3-kinase (PI3K), a key proximal step in insulin's metabolic signaling, was said previously to be severely blunted in Hmga1-/- animals [6], whereas phosphorylation of Akt, the next step in the pathway, is increased in these mice according to Chiefari et al. [1] (Figure 1). Moreover, Rbp-/- mice show enhanced insulin-induced phosphorylation of insulin receptor substrate 1 and activation of PI3K, also seemingly at odds with the new findings [9]. These considerations should motivate further signaling studies.
'HMGA1opathy': a novel insulin resistance subphenotype?
As with all interesting results, new lines of enquiry are suggested by the current findings. Mice with 10% of normal Insr expression would be expected to be severely insulin resistant, yet Hmga1-/- mice are insulin hypersensitive. After administration of RBP they remain more insulin sensitive than wild-type controls, indicating that suppressed RBP in the knockouts accounts for only part of their insulin sensitization relative to mice with primary Insr defects. This raises the question of whether a wider perturbation of the secreted proteins related to insulin action could be at play. Germane to this is the finding that the generalized IR of humans with INSR mutations is biochemically distinct both from the IR of patients with other monogenic forms of severe IR and from 'common' IR, with adiponectin (from adipose tissue), insulin-like growth factor binding protein 1 and sex hormone binding globulin (IGFBP1 and SHBG, both from liver) and liver fat content all serving as good discriminators of the groups [7, 10] (Table 1). It seems plausible that HMGA1-deficient humans or mice may show a third subphenotype of IR with a unique profile of insulin-responsive secreted factors, a possibility given credence by the finding that HMGA1 directly influences IGFBP1 expression, for example. Clarifying this may not only help to understand the complex metabolic derangement of HMGA1 deficiency, but may also define its unique biochemical 'fingerprint' that will aid ascertainment of further cases for study.
In the continuing struggle to understand fully the primary metabolic perturbation in T2DM, novel pathways and new connections are to be welcomed. Signaling uncertainties notwithstanding, the link between RBP and the unusual metabolic phenotype of the Hmga1-/- mice is intriguing, and the work that led to this finding illustrates the great power of combining biochemistry, genetics and physiology in mice and humans to yield novel mechanistic insights into the regulation of metabolism. The next installment of the story is awaited with interest.
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Chiefari E, Paonessa F, Iiritano S, Le Pera I, Palmieri D, Brunetti G, Lupo A, Colantuoni V, Foti D, Gulletta E, De Sarro G, Fusco A, Brunetti A: The cAMP-HMGA1-RBP4 system: a novel biochemical pathway for modulating glucose homeostasis. BMC Biol. 2009, 7: 24-10.1186/1741-7007-7-24.
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Takata Y, Kobayashi M, Maegawa H, Watanabe N, Ishibashi O, Shigeta Y, Fujinami A: A primary defect in insulin receptor in a young male patient with insulin resistance. Metab Clin Exp. 1986, 35: 950-955.
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Imano E, Kadowaki H, Kadowaki T, Iwama N, Watarai T, Kawamori R, Kamada T, Taylor SI: Two patients with insulin resistance due to decreased levels of insulin-receptor mRNA. Diabetes. 1991, 40: 548-557. 10.2337/diabetes.40.5.548.
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Brunetti A, Manfioletti G, Chiefari E, Goldfine ID, Foti D: Transcriptional regulation of human insulin receptor gene by the high-mobility group protein HMGI(Y). FASEB J. 2001, 15: 492-500. 10.1096/fj.00-0190com.
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Reeves R, Beckerbauer L: HMGI/Y proteins: flexible regulators of transcription and chromatin structure. Biochim Biophys Acta. 2001, 1519: 13-29.
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Foti D, Chiefari E, Fedele M, Iuliano R, Brunetti L, Paonessa F, Manfioletti G, Barbetti F, Brunetti A, Croce CM, Fusco A, Brunetti A: Lack of the architectural factor HMGA1 causes insulin resistance and diabetes in humans and mice. Nat Med. 2005, 11: 765-773. 10.1038/nm1254.
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Semple RK, Sleigh A, Murgatroyd PR, Adams CA, Bluck L, Jackson S, Vottero A, Kanabar D, Charlton-Menys V, Durrington P, Soos MA, Carpenter TA, Lomas DJ, Cochran EK, Gorden P, O'Rahilly S, Savage DB: Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis. J Clin Invest. 2009, 119: 315-322.
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Kulkarni RN, Bruning JC, Winnay JN, Postic C, Magnuson MA, Kahn CR: Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes. Cell. 1999, 96: 329-339. 10.1016/S0092-8674(00)80546-2.
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Yang Q, Graham TE, Mody N, Preitner F, Peroni OD, Zabolotny JM, Kotani K, Quadro L, Kahn BB: Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes. Nature. 2005, 436: 356-362. 10.1038/nature03711.
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Semple RK, Cochran EK, Soos MA, Burling KA, Savage DB, Gorden P, O'Rahilly S: Plasma adiponectin as a marker of insulin receptor dysfunction: clinical utility in severe insulin resistance. Diabetes Care. 2008, 31: 977-979. 10.2337/dc07-2194.
RS is funded by the Wellcome Trust (Intermediate Clinical Fellowship 080952/Z/06/Z).
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Semple, R.K. From bending DNA to diabetes: the curious case of HMGA1. J Biol 8, 64 (2009). https://doi.org/10.1186/jbiol164
- Insulin Resistance
- Retinol Binding Protein
- Enhance Insulin Sensitivity
- Severe Insulin Resistance
- HMGA1 Expression


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We can daydream about alien invasion, killer robots, and rampaging genetic mutations, but the world is more likely to go on until something like this happens: the death of a star.
Sure, we'll all be long-dead by the time it happens, but it's nice to image that our sun will look nearly as pretty as this remnant of a star that died 5,000 years ago in the Large Magellanic Cloud. This image is the result of a compositing of images from the Hubble telescope (the yellow and purple bits) and the Chandra X-Ray Observatory (in blue).
For those of you who prefer the doom and gloom theory of our solar system's demise, you can imagine that this is a giant star corpse, which would directly lead to the formation of giant star zombies, heading our way any second.
Our sun's death will likely be a lot less spectacular. This particular solar demise is a core-collapse supernova, which occurs when a star at least eight times the size of Sol runs out of fuel. Without materials to power the nuclear fusion at its core, the star tries to fuse iron into heavier elements. That trick never works.
Instead, it speeds up the stars collapse, eventually resulting in an explosion so massive it can lead to the creation of neutron stars and black holes.
Our sun will probably just quietly fizzle out. Knowing humans, it'll have something to do with us figuring out how to mine it or something.
Knowing humans, tickets will be available for the show.
Beautiful Supernova Violence [Discovery News]


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Newtown parents urge New Jersey to limit on gun magazine capacity
TRENTON, N.J. (AP) -- Parents of four of the 20 children killed in the Connecticut school shootings in December stood with the New Jersey Assembly on Tuesday to urge the Senate to limit the number of bullets in ammunition magazines.
Their plea came as a Senate committee considered several measures designed to strengthen state gun laws -- but not a proposal to limit magazine capacity to 10 bullets, five less than state law now allows. The Assembly passed the bill in February.
Nelba Marquez-Greene, whose daughter, Ana, was among those killed at Sandy Hook Elementary School in Newtown, reminded lawmakers that 11 children were able to escape as the shooter reloaded.
"Outside of a shooting range, the only use for large-capacity magazines is to kill as many people as possible," Marquez-Greene said at a news conference. "While there are many unanswered questions about Dec. 14, we know that lives have been saved when a shooter has had to stop and reload."
Nicole Hockley, whose 6-year-old son Dylan also was killed, noted that gunman Adam Lanza shot 154 bullets in four minutes and was carrying 30-round capacity magazines, having left smaller capacity magazines at home. Dylan's classroom was the one from which 11 children fled when Lanza stopped to reload, she said.
"He was not able to escape," she said. "So I'm one of those parents who ask myself every day ... if those magazines had held 10 rounds instead of 30, forcing the shooter to reload many more times, would my son be alive today?"
Although New Jersey already has the second-strictest gun laws in the country, behind only New York, each branch of the Democrat-led Legislature and Republican Gov. Chris Christie have proposed separate packages of gun violence bills designed to close loopholes in current laws, to address mental illness and gun ownership, and to strengthen penalties for gun trafficking.
One of Christie's bills requires parental consent for a minor to buy or rent some violent video games; the Senate version proposes parents be educated about violent videos because some legal scholars say Christie's proposal won't stand up in court.
Only the Assembly has moved to limit magazine capacity. It's part of a 22-bill package the chamber fast-tracked within two months of the Newtown massacre.
Senate President Stephen Sweeney on Tuesday indicated his unwillingness to go along with a further limit on magazine capacity.
"Twenty years ago New Jersey implemented a limit on the size of ammunition (magazines). For two decades that limit has been effective," he said in a statement. "What we must focus on now is preventing guns from getting into the hands of those who should not have them. That means addressing issues of mental health, background checks, illegal guns, and straw purchases."
Greenwald has said the Assembly should not consider the Senate bills without the magazine limit.
Two North Jersey Democrats, Senate Majority Leader Loretta Weinberg and Sen. Nia Gill, have introduced legislation that would limit ammunition magazines to 10 rounds. But their bill is not part of Sweeney's package, and it's not known whether the Senate president will agree to give the bill a hearing.
Christie hasn't said what he'd do if a magazine limit reaches his desk, but it was not among the recommendations of an anti-violence task force on which he based his recommendations.
His opponent in the governor's race, Sen. Barbara Buono, said after meeting privately with the victims' families that she will do whatever she can as senator to advance the magazine limit and would put the full thrust of the governor's office behind enacting the limit if elected in November.
Sweeney also met with the families.
National Rifle Association lobbyist Darin Goens, meanwhile, said the Senate hearing was typical of those he has attended in other states.
"You don't see the criminals. You don't see the drug dealers (at the hearing)," he said. "They don't care what you pass. They're going to continue to break the law, no matter what we do today in this building. It's only going to affect the law-abiding citizen and it's going to do nothing to impact crime."
He said the Legislature's reaction was also typical: pass some bills so lawmakers can say they did something -- even if their action will have no effect on violence.


text:
VZ ONLINE GAMES - Spiele für Unterwegs
2020! Tetra
2020! Tetra is the latest and greatest version of the famous puzzle game Tetris. In this amazing game, you get to experience a unique and fun version of Tetra. You have to fill horizontal lines with blocks dropping from the top of the screen to remove them and to score. You will lose the game if the blocks reach the top of the screen. This version adds cool boosters to the mix that help you to gain a better score and to get out of bad situations. 2020! Tetra is one of the most entertaining puzzle games so don't miss the chance to show off your high score! Play 2020! Tetra now for free and enjoy using the new boosters!
Puzzle Games, Classic Games, Board Games
Loot the King
The legend of Robin Hood has inspired countless people. Now it is your turn to follow in the footsteps of Robin Hood and steal as much as possible from the King and give it to the poor.
Skill, Puzzle Games
Crossy Path
Crossy Path is a tricky and highly addictive brain teaser game that requires visual thinking and quick decision making. The player has to reach the exit point of a puzzle while navigating through what can only be described as Escheresque levels. The geometric figures in this game might not be able to exist in reality but they will for sure make you feel like your brain is melting for real. Are your quick enough to find your way through the levels? Can you think quick under pressure? Play Crossy Path now for free and step into the realm of imagination! You will find tons of fun and fascinating geometric puzzles!
Skill, Puzzle Games
Animals & Colors
Animals and Colors is a charming free online brain game that offers plenty of challenge and family fun. Friendly animals are displayed on screen in a whole slew of varying colors, right alongside a question. You must pay attention and answer correctly as fast as you can. The game calls for you to match the animal, or even match the colors on screen. It's like the age old memory game where you have to recall pictures, only with cute little animals instead. At the conclusion, this online puzzle game will tell you how fast your total reaction time is. What are you waiting for? Get out there and play so you can get some brain exercise!
Skill, Games for Girls
Farm Day
A typical farm is for sure not the tidiest place. But the farm in this classic hidden object game is a complete mess. The owner is not only looking for tools but also for his animals and it is your job to find and collect them as fast as possible. While your time is limited you can add a few seconds to your time bank if you happen to find a clock. Also make sure to grab any gold coins you come by. These coins help to build your farm or to buy some cool extras. Play Farm Day now for free and enjoy your day the countryside!
Puzzle Games
Crazy Birds 2
The Crazy Birds are back! Once again they fight to defend themselves against the pigs that want to expel the birdies from their own land. The pigs did set up fortresses already, but these birds wouldn't be known as Crazy Birds, if some walls could hold them back! Whether it's wood or stone, for those birdies it doesn't matter, as they just dive into the walls head first and crush them. And if they fail there always even crazier birds to follow. Use the different abilities of the crazy birds to defeat the army of enemy pigs. Play Crazy Birds II now for free! Set up the slingshot and get ready to aim, shoot and destroy all the enemy structures and the angry pigs.
Skill, Action Games, Arcade Games
No Dots
No Dots is the quintessential puzzle game where you need ouside-the-box thinking, a colorful and fun brain teaser that is easy to pick up but offers deep and entertaining gameplay for endless hours. On a six by six board you have to place colored badges straight or around the corner and try to create matches of three or more badges of the same color. The more badges you manage to match and remove the more points you score. With time more and more colors will come into play and it will get hard to place them on the board without blocking yourself. Play No Dots now for free and make sure to cancel your plans for the coming days - you will not able to stop playing!
Puzzle Games, Arcade Games
Candy Rain 4
The Sweetest Candy Puzzle Game Ever: Candy Rain 4. Enjoy the best candy match and candy crush puzzle! Match three or more candies to have magical combos and to advance in the hundreds of levels! Be careful, It is not that easy to match,collect and crush candies while your moves are limited! Do not worry, your skills along with sweet and colorful boosters like swap,candy crusher will help you in the way! No more crushing same old candies, breaking diamonds, crunching cookies or farming! It is time for a brand-new candy themed puzzle with amazing combos, levels full of surprise gifts and exciting social leaderboard to compete with your friends and competitors! Get ready for the cutest rain of all time! Time for brand new Candy Rain 4!
Puzzle Games, Games for Girls
In Shape the player has to find the right shape from a selection to solve an equation. An equation without numbers? Yes, these puzzles are all about adding and subtracting forms. You need to think quick about what piece would complete the shown shape. And quickly means very quickly. You are low on time and after figuring out the solution you still have to find the missing piece from a selection shown on the bottom of the screen. To set a record in this game you need to be highly intelligent and to show keen perception. Do you have what it takes? Play Shape now for free, the highly addictive gameplay will keep you entertained and engaged for a long time!
Skill, Puzzle Games
Mahjong Frenzy
Mahjong Frenzy is the ultimate mahjong challenge. Usually, the legendary puzzle game is played without time limits but Mahjong Frenzy kicks the experience to the next level as it is all about clearing the board as fast as possible. The faster you remove blocks from the board the more points you will earn as you trigger a multiplier that goes up and up. Only by keeping this multiplier at the maximum you will be able to score enough points to unlock the next of the fifteen stages. Play Mahjong Frenzy now for free and make your way through fifteen levels of epic entertainment!
Board Games
Train Tycoon
Command your own train empire! Solve tricky puzzles and make sure that your train can get to the goal without any crashes!
Strategy Games
The Shape
In The Shape the player has to find the right shape from a selection to solve an equation. An equation without numbers? Yes, these puzzles are all about adding and subtracting forms. You need to think quick about what piece would complete the shown shape. And quickly means very quickly. You are low on time and after figuring out the solution you still have to find the missing piece from a selection shown on the bottom of the screen. To set a record in this game you need to be highly intelligent and to show keen perception. Do you have what it takes? Play The Shape now for free, the highly addictive gameplay will keep you entertained and engaged for a long time!
Puzzle Games
Do you have a good spatial ability? Move the Snowman parts together to finish the level! Take care of rocks and fire and make your own strategy to win!
Puzzle Games, Xmas Special
Bubble Shooter Saga 2 - Team Battle
Bubble Shooter Saga 2 is the latest edition of the famous bubble shooting arcade game. The goal of the game is to help the cute, little teddy to solve 90 all new challenging levels. Each level features fresh ideas and a different layout so all challenges will be a fun experience. The gameplay remains simple - hit at least two or more colored bubbles with a bubble of the same color to remove them from the board. The more bubbles you manage to destroy with one shot, the more coins you get. Use the coins to buy boosters which will help you to beat the level. Play Bubble Shooter Saga 2 now for free and experience one of the best bubble shooting games online!
Skill, Puzzle Games
2020 Plus
2020 Plus is the latest version of this classic block puzzle game. Your task is to place groups of three randomly formed blocks strategically on the board so that they fill complete rows or columns. Once you have placed all three blocks three new blocks will appear. As soon as a row or column is completely filled, the blocks placed in it get cleared. Each completed row or column will also give you points. Delete multiple rows or columns at the same time or in a row to earn bonus points. The game will be over when there is no more space left to place a block. Get the highest score possible, try to unlock medals and achievements and to beat the records of your friends. Play 2020 Plus now for free and experience the most addictive version of this endless puzzle game ever!
Puzzle Games
Get Those Sheep
As a shepherd, you need to take care of all the sheep! Bring them back to the farm in a numerical order, and as fast as possible!
Puzzle Games
Tune your brains! Solve exciting puzzles and compete for the best score. 4 puzzle types are waiting for you, try to score in each!
Skill, Puzzle Games
Blue Box 2
Connect two blue blocks together to move to the next level! Remove other objects by clicking them, but dont drop the top blue block on the ground!
Puzzle Games
Twins Family
The twins in this fascinating puzzle game share a very special connection. If you bring them together they fusion together all the twins in the family to make them happy. Also grab the stars to get additional points!
Puzzle Games, Skill, Board Games
Greedy Sheriffs
Help the Greedy Sheriffs to solve puzzles and collect the diamonds in this brilliant adventure game. Your objective is to enable every sheriff to plunder a beautiful gem and to set the shortest and most efficient path through a level . The fewer moves you use and the closer you get to the optimal path, the more stars you will earn. Sometimes you will have to make clever use of plates that lift or lower stones and sometimes you have to bear in mind, that some fields can only be passed once before they start to crumble. Play Greedy Sheriffs now online and absolutely free and find out, if you can collect all the stars!
Puzzle Games, Skill
Berry Bug
Bob the adorable bug dreamed of delicious strawberries day in, day out! Help him to solve his way through the level by collecting as much strawberries as you can! Unlock the endless mode and beat up the highscore!
Puzzle Games
Flipping Jellies
Flip Jellies to turn them all into the same color! Sounds easy, right? But This game will push you to your limits. Are you ready for this challenge?
Puzzle Games, Skill, Board Games
Physic Puzzle - Hide Caesar
Play one of the best smartphone games with a real physic engine to secure Cesar now at home or on mobile! Based on popular web mind games and educational games for kids hide Cesar´s physic will quickly become one of your best smartphone games. Place the given objects to secure Cesar´s Coins. When ready a physic rain of nails will drop as you have never seen in any of our other best smartphone games. Try to secure and bring all Cesar Coins home safe. This game is compatible with your HTC Phones, IPhone, Samsung Phones, Windows Phones, HTC Evo, HTC desire, t mobile Phones, Samsung Galaxy S2 or your Gaming Laptop.
Here's the brand-new exciting puzzle arcade experience with Sixagon! The aim is to get the hexagon down the tower block as far as possible to earn more points. Tap the bricks and bring the hexagon down nice and steady in the challenging puzzle! Be careful not to make hexagon roll off the screen! Do not forget to use in-game boosters to support : Game slower, wall builder and many more.. Play more to beat your highscore and gain more stars! Join the fun of challenge map that you compete with your and your competitors score everyday! Way your way through the shop with amazing original designs of Hexas! Sixagon offers you an amazing puzzle experience. Be careful, the game is easy to learn but fun & challenging to master gameplay!Start playing now to join the fun!
Skill, Puzzle Games
Slide the green block until it reaches the green arrows at the other side. Have fun in this crazy puzzle game!
Puzzle Games, Skill
Bubble Blobs
Bubble Blobs is a totally new take on the classical bubble shooter gameplay. Not only does Bubble Blobs beautiful graphics and a joyful soundtrack but unlike other games of the genre it does not add more bubbles after a certain time. Instead the bubbles are added each time you don't manage to combine at least three blobs of the same color. In Bubble Blobs it can make sense to shoot your bubbles at seemingly unimportant areas scoring a low amount of point just to make sure you receive no penalty. Play Bubble Blobs now for free and make your way through all the 50 levels full of fun and challenges!
Skill, Arcade Games
Fruity Annie
Fruits are blocked by branches. Use tools to help Annie collect fresh fruits! Total of 25 levels and 7 tools, all tools can be placed wherever you want! Just use your imagination to pass different levels!
Games for Girls
Mixed World Weekend
Mixed World Weekend is the much-anticipated successor of the most-popular Mixed World that introduced a genre cross-over between platform and puzzle games. In each level you have to throw the red monsters off the platforms while making sure none of your cute creatures falls off. All of your creatures have different abilities that will help you to reach your goal. They can slide over brittle stones to shove the grumpy critters out of the way, grab somebody with a sticky tongue or even jump up in the air and fire a bolt of energy that can be used to destroy walls. Play Mixed World Weekend now for free! With some planning you will be able to finish the game and unlock cool achievements!
Puzzle Games
Hexa Fever Summer
Hexa Fever Summer is the latest version of the popular puzzle game Hexa Fever. In this strategic addictive game, you have to fill the lines of the hexagon with blocks to remove the whole line and gain gems. Like in the original Hexa Fever, you can form either a horizontal or a vertical line. Always think about your next move and pay close attention not to fill the whole board as you will lose if there is not enough space to place any more blocks. If you are ever stuck, use your gems to buy boosters to remove blocks from the hexagon board or to change the figures. Play Hexa Fever Summer now for free at SOFTGAMES and enjoy this addictive puzzle game before the summer is over!
Skill, Arcade Games
Shoot the Stars
Tricky logic game for your mobile phone! Try to hit all stars using trampolins and walls in your near! Find the best way to hit them and try to clear all level!
Jelly Monster
Who can resist a tasty bowl icecream? Apparently not even a one-eyed, red monster made of Jelly can. Navigate your avatar through the levels,collecting all gems and avoid the bombs!
Skill, Puzzle Games
Best Candy Friends
Best Candy Friends takes you into the world of delicious candy and challenging puzzles! This fastastic HTML5 game combines the classic match3 gameplay with cool bonus items and amazing objectives that often require you to think out of the box and find creative solutions. But worry not! Should you not be able to fulfill the level goals within the amount of moves that are on hand, you can always choose to buy some more moves by using the bonus points you collected. In fifty increasingly difficult levels you take up the good fight against the monsters, that want to steal your candy and protect the sweets. Play Best Candy Friends now and enjoy these sweets for free!
Games for Girls, Skill, Board Games
Griddlers Deluxe
Griddlers Deluxe is a logic puzzle game where you have to color blocks to reveal pictures and patterns hidden in the grid. Other names for these paint by pixel style puzzles are Nonogrames, Hanjie or Japanese Crosswords. The numbers in the puzzles are show you how many unbroken lines of filled-in squares there are in any given row or column. You should start every puzzle with coloring the blocks that are undoubtedly colored and then deduct the placement of other blocks. Two different control sets make Griddlers Deluxe easy to play on mobile, tablet and desktop Play Griddlers Deluxe now for free, try to solve all the puzzles and find the hidden patterns!
Puzzle Games, Board Games, Arcade Games
Magic Bunnies
Magic Bunnies unites two concepts that seem totally different at the first glance in one free online game. Tetris meets the classic match-3 gameplay! Play with the bunnies in this amazing puzzle game and choose from three super fun game modes.
Puzzle Games
2020 Connect
2020 Connect is the most addictive logic puzzle you've ever seen! The player's task is to place at least four blocks with the same number on it next to each other so they get merged. 2020 Connect takes the best ideas of games like Merged and 2048 and turns it into a total blast. Merging more than four blocks will reward you with coins that later can be spend to purchase cool boosters. Take your time, plan ahead and think for a long as you need to, there is no hurry. Play 2020 Connect now for free! How far can you make it? Will you be able to get the legendary 8192 blocks to merge?
Skill, Puzzle Games, Board Games
Secrets of the Carpets
Go on an epic adventure and find the secrets that are hidden below the carpets in this free online puzzle game. Collect the gems to unlock the next level and try to pick up as many stars as possible on your way. If you roll up any carpet you will most likely find something interesting that can help you to solve the level - or block your way to the diamond if you don't pay enough attention. While the puzzles get more and more complex you will come along items like the magic wand, that can remove objects from a carpet or keys and buttons that open up the lock that protects the diamonds. Play Secrets of the Carpet now and make your way through this beautiful adventure!
Puzzle Games, Classic Games, Skill
2020! Jelly Time
2020! Jelly Time is the latest edition of the successful puzzle game 2020. In 60 challenging and fun levels, your mission is to fill the horizontal and vertical lines with the jelly shapes to clear the line and reach your target score. Be aware not to lose the level by running out of moves before reaching the goal. This game doesn't only have a jelly theme but also has boosters which will help you if you are ever stuck. The cool boosters are changing shapes, clear one field, clear one type and clear a whole area. With its beautiful interface and engaging levels, you will not stop playing 2020 Jelly Time until you finish it. Show off your skills in this challenging and fun puzzle game. Play 2020 Jelly Time now for free!
Puzzle Games
Coconut Beach
You are in paradise, enjoying the sun and sitting under a coconut tree. Suddenly you decide to collect coconuts by blowing them of the tree, let them role and bounce until they are finally in your basket. Puzzle your way through many interesting levels at Coconut Beach.
Puzzle Games, Skill
Feed the Figures
Feed the figures to make them green and happy in this fun puzzle game! Don't forget to feed each of the figures correctly!
Skill, Puzzle Games
Try to solve the interesting puzzles that Boxed has prepared for you! You have to move boxes to certain positions on the board with as less moves as possible. Sounds easy, but its surprisingly addictive!
TOP Games, Puzzle Games, New Games, Skill


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SAMJ: South African Medical Journal
On-line version ISSN 2078-5135
Print version ISSN 0256-9574
SAMJ, S. Afr. med. j. vol.101 n.9 Pretoria Sep. 2011
Caring for public health managers reaps dividends
Social work, psychology and the 'softer' sciences may take a bashing at the hands of those who kneel at the altar of hard data, but in the Eastern Cape - emerging from a morass of historical intrigue and corruption - they're proving effective.
Take a cohort of stressed district health managers in resource-poor settings whose demotivation and burn-out contribute directly to poor patient health outcomes. Add an intensive listening skills and team building workshop hosted by a social worker with her Master's in Public Health.1
The result? The districts run by the newly empowered local leaders are suddenly removed from the 'problem district' chart at head office in Bhisho or Pretoria. What happened? The clouds of perception have shifted as each member of the team realises that the locus of power and change lies far closer to home than they thought. One word of warning from the facilitator herself, however; to be sustainable the workshop, now in sudden demand across the Eastern Cape, has to be part of a 'basket of interventions'. We hope that this first significant and innovative breakthrough is appropriately supported to give it the 'legs' it so badly needs.
Prostatic cancer and screening
Having been brought up on the hopes of the promised benefits of screening for cancer, one may see anything that challenges the potential utopia as a major loss. However, the years have contributed to a much better understanding of the many different kinds of cancer and their complex relationships with genetics and the environment. Hopes were high following discovery of the value of measuring the prostate-specific antigen (PSA) to determine the activity of prostate cancer.
Heyns and colleagues2 evaluated the presenting features and treatment outcomes of prostate cancer in men aged <50 years in their region, where PSA screening is not readily available and most men present with symptoms. They found that men <50 years presenting with symptoms due to prostate cancer had significantly higher-risk disease, higher mean PSA and poorer prognosis than men aged >50 years. They conclude that to diagnose prostate cancer at a potentially curable stage in men aged <50 years, it is necessary to initiate baseline PSA testing at age 40 and 45 years and to select high-risk men for PSA surveillance in order to diagnose potentially curable cancer in those with a life expectancy >20 - 25 years.
In his editorial, Burns3 considers the evidence of the value of routine screening for prostate cancer. In several countries prostate cancer is the most common cancer in men. An increased risk of prostate cancer is related primarily to age and family history and to a lesser extent to race. Cancer of the prostate is largely a disease of older men, and many cancers detected in asymptomatic patients will be indolent and slow growing and will not shorten life. Treatment for prostate cancer may also leave a significant number incontinent or impotent. From the broader population perspective, and in the light of current uncertainties around the natural history of this disease, screening for prostatic carcinoma in any age group is unlikely to prove cost-beneficial.
Hearing loss in the newborn
In South Africa an estimated 17 babies with a significant permanent bilateral hearing loss are born every day. A study of the public sector has shown that more than 90% of babies born in this country do not have the prospect of early detection of hearing loss. Meyer and Swanepoel4 report on a similar survey conducted in the private sector. Universal hearing screening was only offered by 14% of private sector obstetric units.
All children born with hearing loss have a basic human right of access to human communication. The fact that the overwhelming majority of babies with hearing loss in South Africa will not be screened at birth means late identification and restricted developmental outcomes. Early identification of hearing loss is feasible, and its developmental, academic, vocational and economic benefits have been convincingly demonstrated.
HIV and antiretroviral therapy
Three papers5-7 address very different topics concerning antiretroviral therapy (ART) in South Africa.
No pharmacokinetic data exist for premature infants receiving single-dose nevirapine (NVP) for prevention of mother-to-child transmission (PMTCT) of HIV. Mugabo and colleagues5 therefore investigated the plasma concentrations of nevirapine in premature infants exposed to single-dose NVP for PMTCT of HIV-1. Their data support an NVP dosage of 2 mg/kg for infants born before 37 weeks' gestation. In term infants whose mothers do not receive intrapartum NVP, they recommend giving two doses of NVP, one immediately after birth and a second 47 - 72 hours later, but this may not be necessary in premature infants.
Geddes et al.6 achieved good outcomes using a tailored approach to PMTCT in a resource-limited setting, but longer-term follow-up of mothers' and babies' health presents a challenge.
Hurley and colleagues7 studied the anthropometric changes and perceptions of body weight in adults initiated on ART. They found a strong association between perception of body weight in people living with HIV, their desire to gain weight and their actual weight gain on ART. Lipodystrophy, weight gain and truncal obesity are common after initiating ART.
1. Bateman C. Re-invigorating long-neglected rural health workers. S Afr Med J 2011;101:618-620. [ Links ]
2. Heyns CF, Fisher M, Leucona A, van der Merwe A. Should baseline PSA testing be performed in men aged 40 to detect those aged 50 or less who are at risk of aggressive cancer? S Afr Med J 2011;101:642-644. [ Links ]
3. Burns DG. Prostate cancer - is screening the solution? S Afr Med J 2011;101:634. [ Links ]
4. Meyer ME, Swanepoel DeW. Newborn hearing screening in the private health sector - a national survey. S Afr Med J 2011;101:665-667. [ Links ]
5. Mugabo P, Els I, Smith J, Rabie H, et al. Nevirapine plasma concentrations in premature infants exposed to single-dose nevirapine for prevention of mother-to-child transmission of HIV-1. S Afr Med J 2011;101:655-658. [ Links ]
6. Geddes R, Giddy J, Butler LM, et al. Dual and triple therapy to prevent mother-to-child transmission of HIV in a resource-limited setting - lessons from a South African programme. S Afr Med J 2011;101:651-654. [ Links ]
7. Hurley E, Coutsoudis A, Giddy J, Knight SE, Loots E, Esterhuizen TM. Weight evolution and perceptions of adults living with HIV following initiation of antiretroviral therapy in a South African urban setting. S Afr Med J 2011;101:645-650. [ Links ]


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