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This appears to be promising because it provides a protocol that allows the agent to be safely transported to its target in order to conduct its attack on the cancer cell. In this particular case, the immune response against the cancer is also triggered which is a far cry from strategies that merely suppress the immune system while attacking the cancer cells generally. This obviously promises to be way more effective.
It is a strategy that could wrestle a cancer into a controlled situation even if it fails to end the cancer. Most approaches are stuck with a do or die attack with cancer recovery a common complication.
Thus an attack directly on the cancer that simultaneously boosts the immune system response is much to be desired. Most other diseases do exactly this when we step in to support the fight.
Hopefully it is flexible enough to be used against all cancers.
'Hitchhiking' Viral Therapy Deals a Double Blow to Cancer
Newswise — Scientists have shown how a promising viral therapy that delivers a double blow to cancer can sneak up on tumors undetected by hitching a ride on blood cells.
The work, led by researchers from the University of Leeds and The Institute of Cancer Research (ICR), reveals how the 'hitchhiking' virus is shielded from antibodies in the blood stream that might otherwise neutralize its anti-cancer properties.
The findings, from a study in patients, suggest that viral therapies like this can be effectively injected into the bloodstream during routine outpatient appointments - just like standard chemotherapy agents – making them potentially suitable for use against a wide range of cancers.
Reovirus is a promising new way of treating cancer that attacks the disease on two fronts. Not only does the virus kill cancer cells directly, but it also triggers an immune response - like a vaccine – that helps eliminate residual cancer cells.
Many patient trials of reovirus are currently underway, including several in the UK led by the same University of Leeds and ICR scientists. Up until now, however, doctors have not been sure about the best way to deliver the experimental treatment. Although the virus can be injected directly into tumors, this is a relatively complicated procedure requiring considerable technical expertise. This delivery method also makes it difficult to treat tumors deep within the body, such as the liver, lungs, pancreas, and stomach.
Researchers had been concerned that reovirus might not reach the tumors it was supposed to treat if it was delivered intravenously, like standard chemotherapy agents are. They had expected that antibodies in the blood would mop up and neutralize the virus before it arrived at its intended target.
But now tests on a small group of patients have shown that this is not the case. In fact, not only did the virus stay active during its journey through the bloodstream but it also homed in on cancer cells, ignoring nearby healthy tissue.
University of Leeds' researcher Professor Alan Melcher, who receives funding from Cancer Research UK, jointly led the study. He said: "It seems that reovirus is even cleverer than we had thought. By piggybacking on blood cells, the virus is managing to hide from the body's natural immune response and reach its target intact. This could be hugely significant for the uptake of viral therapies like this in clinical practice."
Dr Kevin Harrington from The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, who jointly led the study, said: "Viral treatments like reovirus are showing real promise in patient trials. This study gives us the very good news that it should be possible to deliver these treatments with a simple injection into the bloodstream. It would have been a significant barrier to their widespread use if they could only have been injected into the tumor, but the finding that they can hitch a ride on blood cells will potentially make them relevant to a broad range of cancers. We also confirmed that reovirus was specifically targeting cancer cells and leaving normal cells alone, which we hope should mean fewer side-effects for patients."
The study involved 10 patients with advanced bowel cancer who were due to have surgery on tumors that had spread to the liver. All patients were given up to five doses of the reovirus in the weeks before surgery as outpatients.
Blood tests carried out shortly after treatment found the active virus associated with blood cells. Samples taken later showed that the hitch-hiking virus did not overstay its welcome with the cells and was cleared quickly from the system.
When researchers looked at pieces of tissue removed during surgery up to four weeks later, they found 'viral factories' and active virus in the tumor, but not normal liver. This confirmed that the reovirus had been delivered specifically to the cancer after being injected into the bloodstream.
Dr Julie Sharp, senior science information manager at Cancer Research UK, which part-funded the research, said: "This promising study shows that reovirus can trick the body's defenses to reach and kill cancer cells and suggests that it could be given to patients using a simple injection. We look forward to seeing how this research develops and if this could one day become part of standard cancer treatment."
Full details of the work are published today in the journalScience Translational Medicine. The paper covers findings from the U.K. translational clinical trial (REO 013) investigating intravenous administration of REOLYSIN (Oncolytics Biotech) in patients with metastatic colorectal cancer prior to surgical resection of liver metastases.
The work was funded by Cancer Research UK, Leeds Experimental Cancer Medicine Centre, University of Leeds, The Institute of Cancer Research, Leeds Cancer Vaccine Appeal, and the Rays of Hope Appeal.
Further information:
Professor Alan Melcher is available for interview.
Notes for Editors
1. The paper: Adair, RA, "Cell Carriage, Delivery, and Selective Replication of an Onocolytic Virus in Tumor in Patients," is available to journalists at http://www.eurekalert.org/jrnls/scitransmed/. Alternatively, please contact the Science press office on +1 202-326-6440 or firstname.lastname@example.com.
2. One of the UK's largest medical, health and bioscience research bases, the University of Leeds delivers world leading research in medical engineering, cancer, cardiovascular studies, epidemiology, molecular genetics, musculoskeletal medicine, dentistry, psychology and applied health. Treatments and initiatives developed in Leeds are transforming the lives of people worldwide with conditions such as diabetes, HIV, tuberculosis and malaria. www.leeds.ac.uk
3. The Institute of Cancer Research (ICR) is one of the world's most influential cancer research institutes. Scientists and clinicians at the ICR are working every day to make a real impact on cancer patients' lives. Through its unique partnership with The Royal Marsden Hospital and 'bench-to-bedside' approach, the ICR is able to create and deliver results in a way that other institutions cannot. Together the two organisations are rated in the top four cancer centres globally. www.icr.ac.uk and www.royalmarsden.nhs.uk
The Royal Marsden NHS Foundation Trust
The Royal Marsden opened its doors in 1851 as the world's first hospital dedicated to cancer diagnosis, treatment, research and education. Today, together with its academic partner, The Institute of Cancer Research (ICR), it is the largest and most comprehensive cancer centre in Europe treating over 44,000 patients every year. It is a centre of excellence with an international reputation for groundbreaking research and pioneering the very latest in cancer treatments and technologies. The Royal Marsden also provides community services in the London boroughs of Sutton and Merton and in June 2010, along with the ICR, the Trust launched a new academic partnership with Mount Vernon Cancer Centre in Middlesex. www.royalmarsden.nhs.uk
4. Cancer Research UK is the world's leading cancer charity dedicated to saving lives through research. The charity's groundbreaking work into the prevention, diagnosis and treatment of cancer has helped save millions of lives. This work is funded entirely by the public.Cancer Research UK has been at the heart of the progress that has already seen survival rates in the UK double in the last forty years. Cancer Research UK supports research into all aspects of cancer through the work of over 4,000 scientists, doctors and nurses. Together with its partners and supporters, Cancer Research UK's vision is to beat cancer.For further information about Cancer Research UK's work or to find out how to support the charity, please call 0300 123 1861 or visit www.cancerresearchuk.org. Follow us on Twitter and Facebook
5. Oncolytics Biotech Inc.
Oncolytics is a Calgary-based biotechnology company focused on the development of oncolytic viruses as potential cancer therapeutics. Oncolytics' clinical program includes a variety of human trials including a Phase III trial in head and neck cancers using REOLYSIN, its proprietary formulation of the human reovirus. For further information about Oncolytics, please visit: www.oncolyticsbiotech.com
Professor Alan Melcher is available for interview.


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Home > Used Cars - Centerville, OH
Used Cars – Centerville, OH
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subset: commoncrawl


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Type a word or phrase in the search field below. If you are unable to find the
information you are looking for, please contact us.
Authority issued by the State of New Mexico Public Regulations Commission to allow for- hire carriers to haul property from point to point in the state of New Mexico. The following are required to have a Warrant:
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Governor Michelle Lujan Grisham


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There are many ways to approach the problem of limited access to essential pain medicines. Our work centers on the mechanism of access approach and we've developed a MORPHINE framework to describe how we think about and tackle problems in different countries.
The world is full of problems we can't solve. Millions suffer from diseases that will require new discoveries or inventions to treat. But more than 200 years ago, we developed a safe, plentiful, inexpensive, and effective drug to safely treat moderate or severe pain.Follow @treatthepain


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Product DescriptionThis is a cast thermoset resin based material, made polyester resin cast in tubes. This material is non toxic material as is suitable for a wide variety of applications, such as: Musical instruments, writing instruments, interior design, high end household accessories, hobby/craft, cutlery, military and bush craft knives, furniture manufacture and restoration and fashion.
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NEW YORK (CNN/Money) -
The war with Iraq may not have been about oil, but the post-war rebuilding period sure will be. Iraq has the capability of being an oil producer to rival Saudi Arabia, but getting there could take many years, billions of dollars and a little bit of bickering.
Iraq has 112.5 billion barrels in proven reserves, the second-largest in the world, and possibly 200 billion barrels more in unexplored regions, according to some estimates.
And Iraq's oil also is more easily accessible than in some regions of the world. No need for tricky deep-sea drilling, no worries about the habitats of Arctic caribou -- Iraq's oil is close to the surface of flat, featureless terrain.
Though this wealth of oil has never been fully tapped -- the Western desert has hardly been explored, only 15 of Iraq's 73 oil fields have been developed, and only about 2,000 wells have been drilled, compared with about 1 million in Texas -- the country was able to produce about 3.5 million barrels of oil a day before the Gulf War in 1991.
But much of Iraq's infrastructure was damaged during the war, and the economic sanctions that followed kept Iraq from getting the latest technology, spare parts and investment for its oil fields throughout the 1990s.
"Oil experts acknowledge that Iraq's oil sector is being held together by 'Band-Aids,'" said a recent study by the James A. Baker III Institute for Public Policy of Rice University.
As a result, Iraq's production capacity has been steadily shrinking, from about 3.5 million barrels a day in 1990 to about 2 million barrels a day in 2002.
And some of the methods used to keep the oil flowing -- including "water flooding," in which lighter, refined oil products are pumped into oil reservoirs to push the crude oil to the surface -- may have done long-term damage to the oil reservoirs, according to Saybolt International, a Dutch consulting firm that has monitored Iraq's oil infrastructure for the United Nations.
Additionally, the Baker Institute study warned that sudden production shutdowns -- which might have occurred at many fields during the latest war -- could do even more damage to oil reservoirs.
Simply returning Iraq's production capacity to the pre-1991 level of 3.5 million barrels a day will take an initial investment of $5 billion and cost another $3 billion per year for every year after that, according to the Baker Institute study.
Before the war, Iraq had high hopes for tripling its production capacity to more than 6 million barrels a day, which is entirely possible, and would make Iraq the world's third-largest oil producer after Saudi Arabia and Russia.
But don't hold your breath waiting for that to happen any time soon.
"To get to 6 million barrels a day will require $30 billion to $40 billion in investment, and it assumes a bull market for oil," said Rachel Bronson, director of Middle East studies at the Council on Foreign Relations, a Washington think tank. "If you just start doubling production, but demand stays the same, that's wasteful."
What's more, Iraq is a founding member of the Organization of the Petroleum Exporting Countries (OPEC), the cartel that controls much of the world's oil production. OPEC sets a limit on Iraq's production at 3.2 million barrels a day, and Iraq likely would have to leave OPEC to produce more.
Leaving OPEC could make exporting oil more difficult, since other OPEC nations in the region, such as Saudi Arabia, could punish Iraq by refusing to allow oil to be piped or transported through their territory.
The war also has made Iraqi oil production more difficult. The Wall Street Journal reported recently that Iraqi workers at the Rumaila oil field, the nation's biggest, are only slowly coming back to work, at the invitation of the U.S. Army Corps of Engineers and Halliburton Co.'s Kellogg Brown & Root unit, which is helping the Army repair the oil infrastructure.
What's more, looters have run off with much of the property of Iraq's state-run Southern Oil Co. (SOC), which runs the Rumaila field -- including the buses used to transport workers.
Before the war, Iraq's entire oil industry -- including exploration, oil-field construction and repair and exportation -- was handled by state-run companies such as SOC, under the umbrella of Iraq National Oil Co. (INOC), a state agency.
All official oil sales were made through the United Nations "oil-for-food" program, and the proceeds went to buy food and humanitarian relief and compensate victims of the first Gulf War.
In the long run, a new Iraqi government could end up controlling Iraq's oil production again, with some assistance from private companies, and oil revenue could be handled by the government, if international sanctions are lifted. But in the months and years immediately following the war, it's unclear who will end up controlling Iraq's oil.
The U.N. hasn't yet weighed in on whether or not it will renew the oil-for-food program, and it has made no effort to take control of the oil rebuilding. The U.S. government, which could argue it's responsible under the Geneva Convention for restoring Iraq's oil production to pay for humanitarian relief, already has said it intends to take bids for the short-term work of rebuilding Iraq's oil fields.
Halliburton (HAL: Research, Estimates) -- which already is working on the oil fields, thanks to a controversial early contract awarded without competitive bidding -- is in a prime position to win the next job, as are other U.S. oilfield services companies. After all, U.S. tax dollars will be paying for this early work, at least until the oil starts flowing again, so it seems unlikely the Bush administration will send that money overseas.
Left out in the cold could be companies from France, Russia, China and other nations, which had up to $20 billion in pre-war development deals with the Iraqi government.
French oil company TotalFinaElf, which has contracts worth up to $4 billion to develop Iraq's Majnoon oil field, has said it's confident its contract will be honored -- but that could depend on who controls Iraq's oil production in the future.


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WASHINGTON – Large specialty pharmacies like the one that triggered a deadly meningitis outbreak last year would be subject to federal safety inspections and manufacturing standards, under a new Senate proposal introduced Friday.
The draft bill is the first Senate effort to address the recent outbreak tied to contaminated compounded drugs that sickened more than 700 Americans and killed more than 50 others.
The wave of deadly fungal infections was identified in September and linked to a large Massachusetts compounding pharmacy, which regulators said was operating more like a manufacturer.
The new proposal would subject such large compounding operations to direct federal oversight by the Food and Drug Administration, rather than state pharmacy boards that have traditionally overseen the space.
Compounding pharmacies mix customized solutions, creams and other medications in doses specified by a doctor's prescription. Over the last two decades though, larger compounding operations have emerged that produce medications in bulk and ship them across state lines.
The New England Compounding Center, which triggered the meningitis outbreak, shipped more than 17,600 doses of its pain injection to 23 states.
Last week, FDA Commissioner Margaret Hamburg said her agency was not aggressive enough in policing the company because of the conflicting patchwork of state and federal laws that govern pharmacies. The Senate bill is designed to clear up that ambiguity.
"By clarifying FDA authority over high-risk compounding practices, this bill will enhance protections for patients taking compounded drugs and help prevent crises like last year's tragic meningitis outbreak," said Sen. Tom Harkin, D-Iowa, who chairs the Senate Health, Education, Labor and Pensions Committee. The bill was drafted with support from Republicans on the committee, including Sens. Lamar Alexander, R-Tenn., and Pat Roberts, R-Kan.
Traditional compounding pharmacies will continue to be regulated by state pharmacy boards. However the bill sets minimum standards for ingredients used by all compounding pharmacies.
The bill identifies "manufacturing compounders" as pharmacies that produce injectable drugs and ship them across state lines without patient-specific prescriptions from doctors. These operations will have to register with the FDA, report the drugs they make and meet standards similar to those required of drug manufacturers.
As the first bipartisan bill in Congress aimed at addressing last year's outbreak, observers say the Senate legislation has the best chance of becoming law.
However, previous congressional efforts to regulate compounders have been scuttled before, stretching back to the 1990s.
In the last attempt, senators including Roberts and Ted Kennedy, D-Mass, circulated a bill in 2007 that would have given the FDA more power to inspect compounders and set standards for sterile medications. But the legislation was abandoned after compounding pharmacists waged a grass-roots campaign against it, visiting Capitol Hill and lobbying in Senate offices.
The industry's main trade group, the International Academy of Compounding Pharmacists, spent about $1 million lobbying Congress in the last decade, according to data from the Center for Responsive Politics.


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6-year-old Colo. boy suspended for kissing girl
CANON CITY, Colo. - A 6-year-old boy has been suspended from a Colorado school for kissing a girl on the cheek.
School officials in Canon City are accusing the boy of sexual harassment and they want it on his school record.
The boy's mother tells KRDO-TV her son was suspended once before for kissing the girl and had disciplinary problems, but the girl did not object to being kissed.
A School District RE-1 official says the repeat offenses meet the school policy definition of sexual harassment and they hope the tough standards will force the boy to change his behavior.


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This video was created when Robert Jeffrey was nine. He writes:
I performed to MADONNA's "VOGUE" in the Summer of 1991 when my parents took me to Hampton Beach Casino in Hampton Beach, New Hampshire. A business in the casino at the time gave tourists the chance to lip-synch to their favorite pop songs in front of a blue screen background, and I was lucky enough to partake that summer.
In honor of the twentieth anniversary of MADONNA's "TRUTH OR DARE" and in celebration of MADONNA's upcoming "W.E.", here is my nine year old self paying tribute to the woman who changed my life and continues to inspire me just as much today as twenty years ago.
Raise your hand if you wish you had a still from this video airbrushed onto a T-shirt. (Or printed in ASCII text!)


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Before the fight started, the HDNet Fights team members gave their predictions for how long it'd take Kazuo Misaki to beat heavy underdog Mike Seal at this past December's "Sengoku: Soul of Fight" event.
The most optimistic estimate? Two-and-a-half minutes. The most shrewd? One minutes and 22 seconds.
Needless to say, Misaki was a pretty heavy favorite at -1100 (to Seal's +600).
Each week HDNet and MMAjunkie.com release a new and exclusive fight from
the ever-growing HDNet Fights video library. Stunning knockouts, slick
submissions, shocking finishes and legendary brawls are the norm for
this weekly feature.
Misaki vs. Seal is no exception.
Misaki (22-11-2 at the time), a two-time Sengoku middleweight title-challenger, looked to snap out of a 1-3 skid. Once one of the world's top-ranked middleweights, he had suffered setbacks to Melvin Manhoef and Jorge Santiago (twice). However, against Seal, oddsmakers gave Misaki an overwhelming 92 percent chance of winning.
Seal (13-13-1), a Mexican fighter who's competed with organizations such as Strikeforce and KOTC, entered the bout with four wins in his previous five fights. But would his recent success make a difference against his veteran opponent?
Check out the embedded clip for the answer.
Each week MMAjunkie.com (www.mmajunkie.com) and HDNet Fights (www.hdnetfights.com) team up for "HDNet Fights Vault," which offer a new and unique video from the organization's ever-growing fight library. The weekly feature is a continuation of a long-standing partnership between MMAjunkie.com and HDNet. For more information on HDNet, which broadcasts more MMA events than any other TV


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Sunfish T-Shirt
Tri-blend (poly/cotton/rayon) Unisex T-Shirt. Made to order. No returns. Ships in 5 - 7 days. Click through photos for size chart.
Orders placed before 1pm are processed the same day from Los Angeles, Monday - Friday, excluding holidays. DUE TO COVID T-SHIRTS SHIP 10-17 BUSINESS DAYS
Email us at firstname.lastname@example.com for an RA# and return shipping label. Returns must be received by us with 21 days of original order date. We will refund your credit card within 2 days of receiving your return minus the cost of the return shipping. Please note, depending on your bank, the funds may take up to 3 - 5 days to show up in your account. You will be emailed once your return/refund is processed. ALL TEES ARE MADE TO ORDER, NO REFUNDS OR EXCHANGES, FINAL SALE.


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Mixed-signal oscilloscopes (MSO) are a powerful type of digital storage oscilloscope (devices that display and analyse the waveform of electronic signals) that can add up to 16 digital channels to an oscilloscope. These types of oscilloscopes are able to extend the types of analysis that can be performed by a standard oscilloscope. The biggest advantage of a mixed signal oscilloscope is that it can allow multiple time-aligned digital and analogue waveforms to be displayed on a single display. Equipment like this enables being able to undertake detailed investigations of embedded systems more easily and efficiently to save time and effort, as well as being able to use them in a variety of environments and applications.
How do mixed signal oscilloscopes work?
MSO are used to test and display voltage signals as waveforms, showing how a quantity of something, for example, beats in a heart rate, changes over time. The signals are plotted on a graph to show the measurement and results of the electronic signal. The quantity is plotted vertically (on what is known as the y-axis) and the time period plotted horizontally (on what is known as the x-axis) and these results can then be used to be analysed.
What are mixed signal oscilloscopes used for?
Mixed-signal oscilloscopes most are commonly used in industries where medical equipment is used. They're also a useful piece of equipment for investigating serial data, power, wideband RF and embedded system mixed-signal designs.
You can use an MSO to watch how signals change in circuits over time and they also allow you to find faults in broken televisions, radios and other similar equipment.


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Schools & Colleges
Department of Otolaryngology, Dentistry and Engineering
Fulbright Specialist Candidate
England 2009
Expertise in global bio enterpreneurship, education, and bioscience technology transfer led Arlen Meyers to the Fulbright Specialist Roster in 2007 and took him on two trips abroad between 2007-12. His work in the Business/Development Office at Kings College focused on comparisons and understandings of differences between the American and British approach to these globally significant areas of research and development. Meyers was also invited to spend time at the NHS Innovation Office in Manchester and the Institute for Medical Devices at Strathclyde.
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Accredited by the Higher Learning Commission. All trademarks are registered property of the University. Used by permission only.


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A Sandwich a Day: Beef Shawarma at Taza Bakery
Reviews of Chicago sandwiches.
It's not just a clever name—Taza Bakery is in fact a bakery. They churn out fresh naan and wonderful samoon by the bagful; baklava and samosas and lemon-heavy spinach pies for meals on the run. But they also have an entire menu for dining in, featuring a $1.50 zaatar pizza, falafel, kebabs, and sandwiches wrapped in fresh lavash bread.
The secret to the beef shawarma ($5.49) is the Meat to Other ratio, which is about 10:1. You have to really dig to find the fledgling strands of lettuce, scant bits of tomato, and white onion slivers. They are like The Experience to the Jimi Hendrix of the shawarma here, which boasts deep flavors you can only get from a potent marinade. It has a sweetness that immediately reminded me of Korean bulgogi, but here the meat then gets accessorized with olive oil, parsley, and tahini. You get a nice mix of crispy bark and tender middle parts, straight from the spit. Huge and filling, I swore I would take half of it home. But some promises are better left in your belly.
Taza Bakery Inc
3100 West Devon Avenue, Chicago, IL 60659 (map)
Josh Conley is single-handedly trying to re-introduce the verb beget into the everyday lexicon. He traveled to Easter Island one Christmas out of sheer irony. He excises a hefty syntax, and shamelessly promotes the color orange. His wife begat him two small children that he regularly belittles HERE.
All products linked here have been independently selected by our editors. We may earn a commission on purchases, as described in our affiliate policy.


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ObamaCare's Secret Mandate Exemption
HHS quietly repeals the individual purchase rule for two more years.
ObamaCare's implementers continue to roam the battlefield and shoot their own wounded, and the latest casualty is the core of the Affordable Care Act—the individual mandate. To wit, last week the Administration quietly excused millions of people from the requirement to purchase health insurance or else pay a tax penalty.
This latest political reconstruction has received zero media notice, and the Health and Human Services Department didn't think the details were worth discussing...
To Read the Full Story


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Our goal at LivElite is to break down barriers in people's lives. That isn't just limited to our opportunity. When you join LivElite, you are not just joining a company; you are joining a community.
From Day 1, a network of distributors and corporate staff is here to support and train you. This team atmosphere taps into the power of network marketing, helping everyone succeed together. At LivElite, you are never in business alone.
The LivElite community challenges what the world says is "normal" and proves day after day that a life without barriers is possible. We are changing the world and making it a better place, whether that's opening the doors of opportunity, helping each other build the skills to succeed, or reaching out to communities around the world through our Lift Elite program. Together, we are a powerful force for good.
"We make a living by what we get. We make a life by what we give." - Winston S. Churchill


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- Position 5 - Greg Gripon
Position 5 - Greg Gripon
Greg Gripon grew up in League City, Texas. He is the son of Lorene and Lynn Gripon.
He was involved in the Future Farmers of America and an active swimmer in the League City Barracudas swim team. Gripon received many awards in the FFA, as well as the Lone Star Farmer degree and attended the League City United Methodist Church.
Gripon is proud to be a hometown Clear Creek High School graduate, Class of 1985. He followed his passion and furthered his studies attending college at Texas State Technical Institute (TSTI), where he achieved his Associates Degree in Floriculture and Ornamental Horticulture Technology.
He is also a graduate of League City's Citizen University and the League City Citizens Police Academy.
Gripon met the love of his life, LaTonnia, while at TSTI and were married in her hometown of Marble Falls, Texas in 1987. After their wedding, they settled in League City to start their lives together and work in the family-owned business. Gripon and his wife are now the current owners of Lynn's Landscaping which was started by his parents in 1951 to serve the League City Area.
The Gripon's were blessed with their first child, Justin Gripon, in 1991 and their second child, Ashley Gripon, in 1995. Their lives were forever changed and blessed beyond measure. Gripon lives every day to what his parents instilled in him: to always have respect, morals and integrity towards others, and to keep the faith.
Gripon was instrumental in the startup of the League City Merchants Business Association which is now better known as the League City Regional Chamber of Commerce. He has also been a proud member of the League City Lions Club since 1990. His wife, LaTonnia, joined in 2002 and his children, Justin and Ashley, are now third generation members.
The entire family volunteers each year with the League City Music Festival and BBQ Cook-off, also known as the Village Fair. He is also the former President of the League City Lions Club and has received the Melvin Jones, Jack Wiech Fellow and Lion of the Year awards. Gripon is also a current board member of the Lions Club and League City Proud and serves as the Chairman of the Music Festival.
Gripon's entire family are extremely proud to have a League City Park named after his father, "Lynn Gripon Park at Countryside."
Gripon believes that League City is truly blessed as one of the most amazing communities in our country! The future of our historic city holds so much hope, love and growth. League City's future has so many vibrant dreams just ready to be put into action.
New businesses are seeking out League City for all of our unique assets. Our town is desirable and attractive to new growth. Dealing with this growth takes serious attention in communicating the much needed foresight in planning. We must have knowledgeable, great employees working for our city that represent our honest values and looking out for the community's best interest, leaving no stone unturned. Planning our future belongs to the community and those who live and play here. As a city council Member, Greg will continue his love and dedication towards League City, as he has done for the past 50 years. He will always be accessible to all the citizens of League City. Greg is an open book that will listen to and hear the desires of all our citizens, and will strive to attend to all the concerns and dreams of League City's proud community.
Email Greg Gripon
Phone: 281-850-0753


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Sophomore Comedy Matches Its Best Adults 18-49 and Adult 25-54 Ratings
"How I Met Your Mother" Posts Season High Adult 18-49 and Adult 18-34 Ratings Delivers Its Largest Audience Since its Season Premiere
THE BIG BANG THEORY delivered its largest audience ever and matched its best adult 18-49 and adult 25-54 ratings while HOW I MET YOUR MOTHER posted season high adult 18-49 and adult 18-34 ratings, according to preliminary Nielsen live plus same day ratings for Monday, Nov. 3.
At 8:00 PM, THE BIG BANG THEORY was first in adults 18-49 (3.8/10), adults 18-34 (3.0/09), second in households (6.1/09), viewers (9.90m) and adults 25-54 (4.5/10, -0.2 behind ABC). BIG BANG THEORY delivered series highs in households and viewers, matched series highs in both adults 25-54 and adults 18-49 and a season high in adults 18-34.
At 8:30 PM, HOW I MET YOUR MOTHER was first in adults 18-34 (3.5/09), tied for first in adults 18-49 (4.1/10, with ABC), second in households (6.0/09), viewers (9.56m) and adults 25-54 (4.5/10). HOW I MET YOUR MOTHER delivered season highs in households, adults 18-49 and adults 18-34 while posting its largest audience since the Sept. 22 season premiere.


text: 7 July 4th Night Time Activities by ImagineToys.com on Friday, July 4, 2014 8:52:00 AM Your 4th of July with Spark with Activity Make 4th of July something special your kids will remember each year and start some traditions. This entry was posted in Creative Kids Arts and Crafts, Let's Play - Kids of All Ages, Toddlers & Preschoolers Playtime, Big Kid Adventures. outdoor activitiesJuly 4th activitiesfun things for kidsactivities for kids4th of JulyIndependence Day


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Braden, Maria. "A Rose by Any Other Name," inWomen Politicians and the Media, 50-62. Lexington: University Press of Kentucky, 1996.
For more than three decades, Margaret Chase Smith served as a role model for women aspiring to national politics. As the first woman to win election to both the U.S. House and the U.S. Senate, Smith cultivated a career as an independent and courageous legislator. Senator Smith bravely denounced McCarthyism at a time when others feared speaking out would ruin their careers. Though she believed firmly that women had a political role to assume, Smith refused to make an issue of her gender in seeking higher office. "If we are to claim and win our rightful place in the sun on an equal basis with men," she once noted, "then we must not insist upon those privileges and prerogatives identified in the past as exclusively feminine."1
Margaret Madeline Chase was born on December 14, 1897, in Skowhegan, Maine—the oldest of six children—to George Emery, the town barber, and Carrie Murray Chase, a waitress, store clerk, and shoe factory worker.2 After graduating from Skowhegan High School in 1916, Chase took jobs as a teacher, telephone operator, and office manager for a woolen mill and on the staff of a small newspaper. In 1930, she married Clyde Harold Smith, an accomplished local politician.3 In 1936, Clyde Smith was elected as a Republican to the House of Representatives for the 75th Congress (1937–1939). Margaret Smith managed his Washington office and also served as president of the Business and Professional Women's Club of Maine. She also worked on behalf of the Maine GOP committee.
In the spring of 1940, Representative Clyde Smith fell ill with a life–threatening heart condition. Realizing that he could not survive the rigors of an election campaign, he persuaded his wife to run for his seat in the general election the following November. Before his death on April 8, 1940, the Congressman told voters, "I know of no one else who has the full knowledge of my ideas and plans or is as well qualified as she is, to carry on these ideas or my unfinished work for the district."4 His seat left vacant with his passing, Margaret Chase Smith declared her candidacy for the special election to serve out his unexpired term in the 76th Congress (1939–1941).5 In the May 13, 1940, Republican special primary, Smith topped her challenger by a more–than 10–to–1 margin, virtually assuring her election to the House in the heavily Republican district.6 Without a Democratic challenger, she won the June 3 special election, becoming Maine's first woman Member of Congress. On June 17, 1940, only a week after being seated in the House, Congresswoman Smith won the GOP primary for the full term in the 77th Congress (1941–1943), garnering more than 27,000 votes and amassing more than four times the total of her nearest competitor.7 Her second primary triumph dispelled a popular notion that voters would abandon her—having believed that by electing her to a brief term they had fulfilled their obligation to seeing her husband's programs through to conclusion.
In the 1940 general election, Smith ran on a platform of military preparedness (including expansion of the navy, which played well in her shipbuilding district) and support for old–age pensions and assistance, which appealed to the state's large elderly population. She portrayed herself as a moderate who, in contrast to liberal feminists, would work within the established order; she employed that argument for many later campaigns. Smith drew upon her experiences campaigning with her husband, particularly his ability to strike up personal relationships with voters.8 Smith won the general election over Democrat Edward Beauchamp, with 65 percent of the vote. After her 1940 campaigns, Smith was re–elected to the three succeeding Congresses with relatively little challenge, defeating her opponents with 60 percent or more of the vote.9
As a freshman in 1940, Representative Smith had hoped to carry on her husband's work on the Labor Committee, but she was instead pushed onto four low–level committees: War Claims; Revision of the Laws; Invalid Pensions; and the Election of the President, Vice President, and Representatives in Congress.10 Though she often broke with her GOP colleagues on important votes, party leaders answered her persistent request for a better committee assignment in the 78th Congress (1943–1945). Smith received a position on the prominent House Naval Affairs Committee—a fair compromise after her strategic request for the highly coveted Appropriations panel. "When I asked for a committee, I asked for Appropriations, knowing that I would not get it," Smith recalled, "I asked for it, because that was the thing to do in those days. You didn't expect to get what you asked for, so you would ask for something that was impossible… . And Naval Affairs was what I wanted; I didn't want Appropriations … I think I was smart."11 In addition to her Naval Affairs duties, Smith served on the Education Committee and the Post Office and Post Roads Committee. After the Legislative Reorganization Act of 1946 merged disparate committees with military jurisdictions, the Congresswoman was assigned to the Armed Services Committee.
Smith was an active member of the Naval Affairs and Armed Services Committees. Her position gave her power to award shipbuilding projects in Maine. It also made her an expert on military and national security matters, leading to her participation in an investigation of the construction of destroyers and the inspection of bases in the South Pacific. In addition, Smith participated in a trip to observe the postwar reconstruction in Europe, North Africa, and the Middle East. Though she expressed concern for the spread of Soviet influence in Eastern Europe, Smith remained wary of domestic communist fears. She voted against legislation to make the House Select Committee on Un–American Activities permanent.
As a member of the Armed Services Committee, Smith passed her landmark legislative achievement in the House: the Women's Armed Forces Integration Act. With a wartime peak enrollment of about 350,000, women were still considered volunteers for the armed services and did not receive any benefits.12 In April 1947, while chairing the Armed Services' Subcommittee on Hospitalization and Medicine, Smith passed a bill giving regular status to navy and army nurses—well–accepted by her House colleagues because it covered women in traditional, "angel of mercy" roles.13 When the Armed Forces Integration Act, providing for the permanent inclusion of all uniformed women in the military, easily passed the Senate in July 1947, Smith faced a greater challenge pushing the bill through the House. Opponents on the Armed Services Committee amended it over Smith's lone dissenting vote, significantly curtailing women's rights and benefits by offering them reserve status. The House passed the committee's version. In an effort to restore the bill's original intent in the conference committee, Smith appealed to her personal friend, Secretary of Defense William Forrestal, who gave her his full backing. Smith prevailed when the House conferees accepted a version of the legislation granting women regular status on June 2, 1948. President Harry Truman signed the bill into law 10 days later, just weeks before he racially integrated the armed forces by Executive Order.14
In 1947, when Maine's senior U.S. Senator, Republican Majority Leader Wallace White, announced he would not seek a fourth term, Smith entered the hotly contested 1948 primary to succeed him. The state Republican Party, stung by Smith's many votes across party lines, opposed her candidacy and supported Maine Governor Horace A. Hildreth in the four–way race. Running on the slogan, "Don't trade a record for a promise," Smith insisted that her legislative achievements in the House were worth more than the campaign promises of her opponents.15 The personal touch that marked her House campaigns also aided in her senatorial bid. As she crisscrossed the state making speeches and meeting personally with constituents, many simply addressed her by her first name, "Margaret," with the kind of intimacy indicative of an old friendship.16 A large corps of Maine women volunteers also greatly aided her shoestring, grass–roots campaign.17 In the June 21 primary, Smith received nearly 64,000 votes, a greater margin the combined votes of her three challengers. After capturing the primary, Smith won a lopsided election, defeating Democrat Adrian Scolten with 71 percent of the vote. Smith's election marked the first time a woman won election to the Senate without the widow or appointment connection and the first time a woman served in both chambers. Smith was re–elected to the Senate three more times by comfortable majorities.18
Despite her experience in the House, Smith needed to earn her seniority in the Senate. In her first term, she received three less powerful assignments: Committee on the District of Columbia, Committee on Rules and Administration, and the Committee on Expenditures in the Executive Departments (after the 83rd Congress [1953–1955], named Government Operations). When Republicans briefly controlled the chamber in the 83rd Congress, Smith earned seats on two prominent committees which no woman had held before: Appropriations and Armed Services. She gave up Government Operations for an assignment on the Aeronautical and Space Sciences Committee in the 86th Congress (1959–1961)—a particularly influential panel at the dawn of the space race with the Soviet Union.19 She maintained a place on these three key panels for the remainder of her Senate career.
Margaret Chase Smith's defining moment in the U.S. Senate came on June 1, 1950, when she took the Senate Floor to denounce the investigatory tactics of the redbaiting Wisconsin Senator Joseph R. McCarthy. In a speech she later called a "Declaration of Conscience," Smith charged that her Republican colleague had "debased" Senate deliberations "through the selfish political exploitation of fear, bigotry, ignorance and intolerance." She said, "The American people are sick and tired of being afraid to speak their minds lest they be politically smeared as 'Communists' or 'Fascists' by their opponents. Freedom of speech is not what it used to be in America. It has been so abused by some that it is not exercised by others."20 Although the speech attracted favorable nationwide attention and was endorsed by six fellow Republicans in the Senate, it did little to restrain Senator McCarthy and his supporters. McCarthy ridiculed Senator Smith on the Senate Floor, and he poured political capital into the campaign of Smith's 1954 GOP rival. Late in 1954, the Senate censured McCarthy for his conduct of the Army– McCarthy hearings, effectively silencing him. Despite Smith's bravery in standing up to McCarthy, her reputation as a political maverick limited her later potential in the Senate. Among the costs were her removal from the Republican Policy Committee and a drop in seniority on the Permanent Investigations Subcommittee of the Government Operations Committee.21
In the Senate, Smith remained more of an independent than a party–line Republican vote. The Senator's meticulous and independent nature was most evident in her rejection of several high–profile presidential nominees. In 1957, after President Dwight D. Eisenhower nominated Hollywood actor, decorated World War II veteran, and army reservist James ("Jimmy") Stewart for promotion to brigadier general, Senator Smith recommended against his promotion. She led an unexpected rejection of Commerce Secretary nominee Lewis L. Strauss in 1959, marking the third time in a century that a Cabinet appointment was rejected and deeply angering the Eisenhower administration.22 Nearly a decade later, Smith enraged the Richard M. Nixon White House when she and fellow Senators rejected Supreme Court nominee G. Harrold Carswell. Smith's independence on high–visibility issues made it hard to categorize her politics and somewhat diminished her influence. On the domestic front, the Senator supported legislation for primarily Democratic initiatives on educational funding and civil rights. However, Smith supported a much more aggressive foreign policy than that of the John F. Kennedy administration. After the Berlin Crisis of 1961, she accused President Kennedy of lacking the resolve to use nuclear weapons against the Soviet Union, chiding the President on the Senate Floor, "In short, we have the nuclear capability but not the nuclear credibility."23 In her long career, Smith became a Senate institution in her own right. From June 1, 1955, to September 6, 1968, she cast 2,941 consecutive roll call votes. Her streak was interrupted only by recovery from hip surgery.
After months of denying rumors that she would seek the top of the Republican ticket or the vice presidential nomination, Senator Margaret Chase Smith announced her run for President in January 1964. "I have few illusions and no money, but I'm staying for the finish," she noted, "When people keep telling you, you can't do a thing, you kind of like to try."24 Smith embarked on her typical grass–roots campaign—losing every primary but picking up a surprising high of 25 percent of the vote in Illinois.25 At the 1964 Republican Convention, she became the first woman to have her name put in for nomination for the presidency by a major political party. Receiving the support of just 27 delegates and losing the nomination to Senate colleague Barry Goldwater, it was a symbolic achievement.
To the surprise of many across the country, Maine voters turned the venerable septuagenarian out of office in 1972, during her bid for a fifth consecutive term. Prior to the election, Smith had given serious consideration to retiring, but charges that she was too old—at age 74—to serve as a Senator had motivated her to run for re–election. The Democratic nominee, Maine U.S. Representative William D. Hathaway, emphasized Smith's age. He also claimed Smith was inaccessible and inattentive to Maine's concerns, citing the fact that she did not maintain an office in the state. Smith lost the election by 27,230 votes, a margin of 53 to 47 percent.26
Smith resettled in Skowhegan to oversee the construction of the Margaret Chase Smith Library Center, the first of its kind to focus its collection on the papers of a female Member of Congress. In 1989, President George H.W. Bush awarded her the Presidential Medal of Freedom, the nation's highest civilian honor. Margaret Chase Smith died on May 29, 1995, at the age of 97, in her hometown of Skowhegan.
1Congressional Record, House, 79th Cong., 2nd sess. (24 July 1946): A4378–A4379.
2On parents' employment, Mary Kaptur, Women of Congress: A Twentieth–Century Odyssey (Washington, D.C.: Congressional Quarterly Press, 1996): 85.
3"Rep. Clyde H. Smith of Maine, Was 63," 9 April 1940, New York Times: 29.
4Quoted in Janann Sherman, No Place for a Woman: The Life of Senator Margaret Chase Smith (New Brunswick, NJ: Rutgers University Press, 2000): 42.
5"Mrs. Smith To Seek Place of Husband," 9 April 1940, Washington Post: 9; "Clyde Smith's Widow Files," 16 April 1940, New York Times: 15.
6"Rep. Clyde Smith's Widow Nominated by Maine G.O.P.," 14 May 1940, Washington Post: 1.
7Patricia Schmidt, Margaret Chase Smith: Beyond Convention (Orono: University of Maine Press, 1996): 108–113; Sherman, No Place for a Woman: 47.
8Sherman, No Place for a Woman: 44–45.
9"Election Statistics, 1920 to Present," http://clerk.house.gov/member_info/electionInfo/index.aspx.
10Susan Tolchin, Women in Congress (Washington, D.C.: Government Printing Office, 1976): 75.
11Kaptur, Women of Congress: 86.
12David M. Kennedy, Freedom From Fear (New York: Oxford University Press, 1999): 776.
13Schmidt, Margaret Chase Smith: 163.
14Harry S. Truman, "Executive Order 9981," Truman Presidential Museum and Library, http://www.trumanlibrary.org/9981.htm (accessed 22 February 2005).
15Hope Chamberlin, A Minority of Members: Women in the U.S. Congress (New York: Praeger, 1973): 143.
16Helen Henley, "Maine GOP Nominates Mrs. Smith for Senator," 22 June 1948, Christian Science Monitor: 5; Josephine Ripley, "Women Hail Smith Victory in Maine," 23 June 1948, Christian Science Monitor: 7.
17Schmidt, Margaret Chase Smith: 181–182.
18"Election Statistics, 1920 to Present," http://clerk.house.gov/member_info/electionInfo/index.aspx.
19The space race began when the Russians successfully launched the first satellite into space. Sputnik I orbited the earth in October 1957. The Russian satellite was followed by the January 1958 launch of the American Explorer I, a small satellite used for collecting scientific data (National Aeronautics and Space Administration, "Sputnik and the Dawn of the Space Age," http://www.hq.nasa.gov/office/pao/History/ sputnik/ (accessed 18 February 2005).
20Congressional Record, Senate, 81st Cong., 2nd sess. (1 June 1950): 7894–7895.
21Sherman, No Place for a Woman: 117–118.
22Chamberlain, A Minority of Members: 146.
23Congressional Record, Senate, 87th Cong., 1st sess. (23 September 1961): 20626.
24Tolchin, Women in Congress: 76.
25"The 1964 Elections," Congress and the Nation, 1945–1964, Vol. 1–A (Washington, D.C.: Congressional Quarterly Press, 1965): 54.
26Office of the Clerk, U.S. House of Representatives, "Election Statistics, 1920 to Present."
View Record in the Biographical Directory of the U.S. Congress[ Top ]
Braden, Maria. "A Rose by Any Other Name," inWomen Politicians and the Media, 50-62. Lexington: University Press of Kentucky, 1996.
Crouse, Eric. An American Stand: Senator Margaret Chase Smith and the Communist Menace, 1948-1972. Lanham, Md.: Lexington Books, 2010.
___. Dear Senator Smith: Small-Town Maine Writes to Senator Margaret Chase Smith about the Vietnam War, 1967-1971. Lanham, Md.: Lexington Books, 2008.
___. "Senator Margaret Chase Smith Against McCarthyism: The Methodist Influence." Methodist History 46 (April 2008): 167-178.
Fitzpatrick, Ellen. The Highest Glass Ceiling: Women's Quest for the American Presidency. Cambridge: Harvard University Press, 2016.
Gallant, Gregory Peter. "Margaret Chase Smith, McCarthyism, and the Drive for Political Purification." Ph.D. dissertation, University of Maine, 1992.
___. Hope and Fear in Margaret Chase Smith's America: A Continuous Tangle. New York: Lexington Books, 2014.
Graham, Frank. Margaret Chase Smith: Woman of Courage. New York: John Day Co., 1964.
Gutgold, Nichola D., "Margaret Chase Smith: A 'Quiet Woman,'" in Paving the Way for Madam President. New York: Lexington Books, 2006.
Harris, Lois Anne. "Margaret Chase Smith: An Examination of Her Public Speaking with Emphasis on the 'Declaration of Conscience, 1950' and the 'Declaration of Conscience, 1970'." Ph.D. dissertation, Southern Illinois University at Carbondale, 1974.
Hutchison, Kay Bailey. "Margaret Chase smith." In American Heroines: The Spirited Women Who Shaped Our Country. New York: HarperCollins, 2004: 210-243.
Kaptur, Marcy. "Margaret Chase Smith." In Women of Congress: A Twentieth-Century Odyssey, 84-101. Washington: Congressional Quarterly Inc., 1996.
Lamson, Peggy. Few Are Chosen: American Women in Political Life Today. Boston: Houghton Mifflin Company, 1968.
Morrison, Dennis L. "Margaret Chase Smith's 1950 Declaration of Conscience Speech." Maine Historical Society Quarterly 32 (Summer 1992): 2-25; 51-55.
Schmidt, Patricia L. Margaret Chase Smith: Beyond Convention. Orono: University of Maine Press, 1996.
Sherman, Janann. "'Senator-at-Large for America's Women': Margaret Chase Smith and the Paradox of Gender Affinity," included in Susan J. Carroll, ed., The Impact of Women in Public Office. Bloomington: Indiana University Press, 2001: 89-116.
___. "'They Either Need These Women or They Do Not': Margaret Chase Smith and the Fight for Regular Status for Women in the Military." The Journal of Military History 54 (January 1990), 47-78.
___. No Place for a Woman: A Life of Senator Margaret Chase Smith. New Brunswick: Rutgers University Press, 2000.
Smith, Margaret Chase. Declaration of Conscience. Edited by William C. Lewis, Jr. New York: Doubleday Co., 1972.
Smith, Margaret Chase, and H. Paul Jeffers. Gallant Women. New York: McGraw-Hill Book Co., 1968.
"Margaret Chase Smith," in Women in Congress, 1917-2006. Prepared under the direction of the Committee on House Administration by the Office of History & Preservation, U.S. House of Representatives. Washington, D.C.: Government Printing Office, 2006.
Vallin, Marlene Boyd. Margaret Chase Smith: Model Public Servant. Westport, Conn.: Greenwood Press, 1998.
Wallace, Patricia Ward. The Politics of Conscience: A Biography of Margaret Chase Smith. Westport, CT: Praeger, 1995.


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Our Events
Love Fireworks? Then you will be dazzled by no less than 6 sets of 4 fabulous firework displays all over the UK this summer. Come and see what has turned into one of the best firework events in the UK. Bring a picnic or grab food and drink at the event, sit down at a stunning stately home and sit back. Soak up the atmosphere and enjoy the music / interviews before a splendid evening of four spectacular displays all precisely set to music.
Each event runs as a competition format with 3 teams firing against each other. The audience have the chance to text vote for the winning display and the result is announced after the final display by organisers MLE Pyrotechnics.
Tickets can be bought online from this website, by ringing MLE the organisers on 01327 876037, or at the entrance gate on the day. If you buy tickets in advance then there is a discount offered. The tickets are posted out to you along with a letter and leaflet for the event. If you pre-order you will receive information about the next event along with a discount code for future years. You can opt not to receive this during the booking process.
Make it an evening to remember for less. Pre book your tickets before the event and you could save up to 20% off the gate price.


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A brief introduction about us and our family
Welcome to our dynamic and colourful world of flowers and plants!
Dynamic because it is a fast-paced world. Not just because we work with fresh products, but also because technology plays a major role in supplying our customers and consumers every day. Colourful due to the way in which our companies, together with their supply chain partners, work with the utmost passion and motivation to produce a perfect product for our international customers. An emotive product that has a positive impact upon people's lives.
Family business through and through
Dutch Flower Group is a unique family company that specializes in the international trade of flowers and plants. With 33 individual companies, we supply all distribution channels, importing wholesalers (who supply florists) and the large-scale retail sector (including supermarket chains, chain stores, petrol pump stations, construction markets and garden centres).
We will be pleased to give you a virtual tour and you may choose the route yourself. This updated website will tell you all about our colourful world. The Corporate Movie will provide you with a look behind the scenes. We hope you enjoy reading the website and watching the movie!
Making life colourful!


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Getting married in Earlestown? Finding the right sports car hire can be stressful and time consuming, so why not let the experts take care of the arrangements.
At weddingtransport.co.uk we've got years of experience in helping couples across Merseyside find just the right vehicle for their special day. And whether you're after a romantic convertible for the happy couple or a fleet of spacious limousines, we're confident that we can do the same for you - and all for an affordable price. Interested? Take a look at our wide selection of sports cars for Hire - we guarantee that we won't disappoint!
In fact, we've got something to suit every budget and taste. Always dreamed of arriving at your wedding in a stunning vintage vehicle? How about a classic Bentley, an elegant Rolls Royce or a timeless Daimler? Or maybe your tastes run a little more modern? From sleek Ferrari sports car to top-of-the-range Mercedes, our vehicles are sure to wow your guests and add a touch of real glamour to your special day. And whichever you choose, you'll enjoy the same fantastic VIP service from the moment you step on board.
At wedding transport we offer our customers a choice of supercar hire, from budget-friendly packages to more elaborate options complete with all the bells and whistles. Want to know more about our great deals on Sports Car Hire in Earlestown? Speak to our team today.


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Turkish Airlines has number of cities at 25% fewer award miles needed for a return, one-way, companion or upgrade awards between December 1-31, 2013.
You can start your trip to/from Turkey or to/from on the cities listed below:
All Domestic Lines
Europe 1: Belgrad , Podgorica , Pristine, Sarajevo, Tirana, Skopje
Europe 2 : Ganja Batumi , Bucharest, Donetsk, Ganja, Konstanta, Lviv, Nahcevan, Odessa, Simferopol, Tbilisi, Vilnius
Europe 3: Basel, Berlin, Bilbao, Birmingham, Bremen, Geneve,Genoa, Dublin, Dusseldorf, Edinburgh, Frankfurt, Friedrichshafen, Hamburg, Hannover, Kazan,Cologne, Kopenhagen, Leipzig, Malaga, Manchester, Moscow, Napoli, Nice, Riga, Rostov, Santiago De Compo, Sochi, Stockholm, Stuttgart, Talin, Turin, Toulousse, Valencia, Wien, Zurich
Central and North Africa:Benghazi, Algiers, Entebbe, Hurghada, Cairo, Kano, Kigali, Misrata, Ndjemena, Sharm En Sheikh, Tripoli, Tunus
Central Asia: Osh, Bishkek, Asqabat, Almaty
Near East: Akabe
Middle East: Isfahan, Kabul, Mazari Sharif, Shiraz
America: Houston
You can access the Miles&Smiles web page for this promotion here.
This could be a way to burn some Miles&SMiles miles if the above mentioned cities are in your plan for December travel.
Here are the terms and conditions of this offer (seems that TK forgot to update the T&C and just copy/pasted the ones from November):
- Promotion will include the award tickets which are issued as of 23 October 2013.
- Promotional award tickets shall be issued for travels between 01 november 2013– 30 november 2013 and travel must be completed between these dates stp
- The validity of the award tickets will be restricted by 30 november 2013 stp
- This promotion is valid for all miles&smiles award tickets, companion tickets and upgrades
- The promotion is validfor all Turkish Airlines capacity controlled and seat guaranteed all economy and business reservation classes. Furthermore promotion is valid forcomfort class on applicable destinations
- The related promotion will be applied only for Turkish Airlines scheduled flights and anadolujet flights stp promotion is not permitted on codeshare flights (tk8000) and for the award tickets issued for the star alliance member airline flights Promotion will be applied for all flights from/to turkey and from/to abroad on the routes stated
- The routes within different award regions cannot be combined
- Return flight can be done from different cities in condition within the same award region
- All rebooking and reroutings can be applied within the same route, class and season until 30 november 2013 no changes is permitted for travels after 30 november 2013 . Mileage refund can be done within 1 year after the ticket issuance date. Any mileage refunds, rebookings and re-routings are subject to penalty.
- One open jaw and one stopover is permitted either on the outbound or on the return segment.
- Tickets can not be issued open.
- The general conditions applied in miles&smiles award tickets are also applicable for award tickets issued in this campaign.
- Taxes must be paid while ticketing


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I just saw a few questions that were in itself perfectly valid, but badly worded. I do not mean the problem where the author is not native English and comes across rather harsh unintentially.
I mean for example this question about double escaping in PHP. Was it right to close this? I can very well sympathize with that, because you reap what you sow and the author asked for it. But that doesn't make the question any less valid, does it?
Another example is this question about disappearing content on eBay. Again, I think the question in itself is okay, just the author seemed to be extremely excited about this "Magic".
These are just two examples that just make me wonder: Are the tools that we have adequate and are they used in the right way?
I'm not saying that they are or are not, I would just like to know if there is really no better way to preserve a good question? Editing requires 2000 rep, while closing requires 3000. So in theory, everyone who could vote close could also edit it.
On the other hand, I agree we shouldn't support laziness and have to decrypt the question from the author. Then again, closing the question to "punish" the author for sloppiness also punishes the people who could use the answer.
People could just ask the same question when they run into the same problem though.
So in theory we have all the tools and options to punish "bad" users and to keep questions at a high quality level. But still I sometimes "feel" that something is slightly off-balance and could need fine tuning, but I'm not sure what.
Or am I just "overreacting" because of 1 in thousands of questions are wrecked that way?
(This is SO specific, no idea about SU or SF)


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4x4 Scenic Off-Road Experience in Jamaicasouth coast Jamaica
Climb aboard and get ready for an awe-inspiring trip to discover the real Jamaica. On this safari through the rugged interior, your eyes will feast on breathtaking natural beauty and you'll learn about the island's rich history and unique culture. There are stops at several local landmarks, including a former slave hospital, which was converted into a church in 1846. We'll take you for a walk on the wild side through lush, tropical foliage to discover hidden waterfalls and jump into crystal-clear, spring water pools. Get off the beaten track and experience the very heart of paradise.
Tour Highlights
- Travel through Jamaica's rugged interior
- See a former slave hospital converted into a church in 1846
- Take a walk to discover hidden waterfalls and jump into spring pools
- Click the video link below to see more!
Important Information
- Confirmation will be sent within 48 hours of booking, subject to availability and minimum tour requirements
- Tour duration is not inclusive of travel time to tour location
- All tours are weather permitting
- Age & Weight restrictions may apply
- Need More Information? Check our FAQs and Terms of Usage
4:30 hours approx.
Minimum Age: 6 year(s)
Days of Operation & Tour Time(s):
Monday:09:00 AM, 02:00 PM
Tuesday:09:00 AM, 02:00 PM
Thursday:09:00 AM, 02:00 PM
Friday:09:00 AM, 02:00 PM
Saturday:09:00 AM, 02:00 PM
Sunday:09:00 AM, 02:00 PM
What to Bring:
- Sneakers
- Change of Clothes
- Towel
- Swimsuit
- Camera
- Sunscreen
Additional Information
- Not recommended for pregnant women
- Not accessible for the physically challenged
- Not recommended for people with back problems or who have had a recent back surgery
- Not handicapped accessible


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Silver Diner - Merrifield
Address:8150 Porter Road
Falls Church, VA 22042
Phone:(703) 204-0812
Of course the Silver Diner serves up classic diner dinners - homemade meatloaf, fresh turkey with mashed potatoes, soups, sandwiches, burgers and Blue Plate Specials – but there's so much more. The Silver Diner also offers contemporary selections such as Cajun Chicken Pasta, Mesquite & Lime Marinated Grilled Salmon, and Veggie Stir Fry with Portobello Mushrooms. The Silver Diner's "Heart Healthy" selections also set it apart. With these items, the Silver Diner has closed the gap between what customers like to eat and what is good for them. All portions remain generous. Breakfast, lunch, dinner, and late night – the Silver Diner has something for everyone, and every taste.


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About AutoLanka Forum
Autolanka forum is a community where you can ask questions and discuss all things related to motoring that you are passionate about.
Welcome to AutoLanka.com
The first online automobile magazine in Sri-Lanka. Best choice for buying and selling cars, vans, bikes, trucks, SUVs, vehicle parts and to be updated with the latest news in Sri-Lanka's Car market. We provide Sri Lankan car market a trusted online marketplace, where you can simply buy and sell cars among thousands of genuine customers. Read more


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Tuscany Travel Guide
Hills of Tuscany © Francesco Sgroi
Tuscany's rolling hills are garlanded with cypress trees, lush vines and olive groves, that make way here and there for sleepy villages and medieval hill-towns. The area rests languidly in the middle of the Italian peninsula, with parts stretching to the coastline of the Tyrrhenian Sea. Snaking through the Tuscan landscape from Florence to Pisa and soaking its thirsty banks is the Arno River. Akin to the gentle flow of a river is the ebb of life in the region: people work in the fields in much the same way as their ancestors did before them, producing some of Italy's finest wines and olive oils. From this same landscape emerges a profusion of art and architecture that has grafted Italy onto the world's cultural map. Tuscany was the birthplace of the Renaissance, a period of unprecedented innovation in art, architecture and humanist scholarship. The grandeur of the High Renaissance was enjoyed during the Medici family's reign, when they commissioned the art and architecture that lives on within the elegant precincts of Florence.
Florence is one of the most popular cities in Italy for tourists, and is widely considered one of the most beautiful cities in the world. It is a dreamy destination made up of cobbled streets, picturesque piazzas, a wealth of Renaissance art and architecture, and some of the best galleries and museums in Italy. It is also a conspicuously Tuscan city, with all the sleepy charm of the region and many worthwhile excursions into the countryside.
Tuscany has a mild Mediterranean climate, with hot summers and cool, wet winters. Winter temperatures range from 50°F to 59°F (10°C to 15°C), while summer temperatures range between 77°F and 86°F (25°C and 30°C). Humidity can be high. The best time to visit Tuscany is in May, September and October.
Become our Tuscany Travel Expert
We are looking for contributors for our Tuscany travel guide. If you are a local, a regular traveller to Tuscany or a travel professional with time to contribute and answer occasional forum questions, please contact us.


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Latest Bollywood film Victory has had its global premier held at
Related article:AFP
Latest Bollywood film Victory has had its global premier held at
Related article:AFP
Posted by Biplob Kishore Deb at 2:13 AM 0 comments
Labels: Amrita Rao, bollywood, bollywood movies, Gulshan Grover, Herman Baweja
To be honest with you, I do not expect a lot from Bollywood in 2009. 2008 was a disaster as year and I don't expect that anything significant will happen in this year too. You may call me pessimistic and even the city with me and I will come you for this matter. But however, let me tell you my reason of being so much pessimistic. But frankly, I do not see any change taking place among Bollywood directors and producers and actors and actresses. But I also cannot find any change in the way Bollywood movies are made. But I do not see any new face that can ensure a big hits in the box office. You might talk about that Katrina Kaif but I do not see any big potential in her. All the but the ding actors of Bollywood are getting old and the presence of Shahrukh Khan does not ensure but he its success in the box office anymore.
Another matter, that is, 2009 is going to be a year of cricket. You know that Indian people are crazy for two things only Cricket and Bollywood. For example, tomorrow, Australia vs South Africa 3rd Test and although
Posted by Tech Support at 9:55 AM 0 comments
Labels: bollywood


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In Detroit, a once bustling city at the center of the US economy, the hedge fund vultures are circling.
But first, a moment of background, employing Naomi Klein's contemporary classic The Shock Doctrine, which tells the story of how purveyors of aggressive capitalism take advantage of crises and public vulnerability in order to push through neoliberal policies and profit-motivated financial arrangements.
Played out in various spheres before and after the book's publication in 2005, the idea of 'disaster capitalism' has been at the center of austerity politics on both sides of the Atlantic (and around the world) in the wake of the 2008 financial meltdown. And now, in places like Detroit, its taking place in US communities at the municipal level as towns and cities hit hard by diminished economies and the slashing of public services are struggling on the edge of bankruptcy.
But, as reporting by Reuters on Wednesday reveals, one city's pain is a possible hedge fund manager's gain.
As Reuters' Tom Hals explains, large private hedge funds, which once preyed on vulnerable companies ripe for liquidation and restructuring, are now taking aim at wounded cities and counties—with no place beckoning "more than Detroit."
This sudden interest in the staid world of municipal debt comes as these so-called distressed funds are looking for new places to put their money. Lucrative corporate bankruptcies have dried up, thanks in part to the Federal Reserve's policy of low interest rates. [...]
But despite the risks, some are already betting hundreds of millions of dollars that there are big returns in cash-strapped governments.
In Detroit, where a previous ploy of the disaster capitalists has already taken hold in the form of an appointed "Financial Emergency Manager"—a position that strips out local government and puts city decision-making into unelected, bureaucratic hands—the people have almost no political avenue to resist the sale of public assets or the manipulation of city debt.
And as Hals notes, "the hedge funds' interest in municipal debt reflects the divergent fortunes of Wall Street and Main Street." He continues:
Distressed debt funds love to jump in when most bail out. But with the coffers of U.S. companies overflowing with cash, there has been a dearth of the debt defaults, bankruptcies and liquidations that such funds normally feast on.
By contrast, a small but potentially growing number of U.S. cities and towns are struggling with pay and pension obligations that they took on in the boom years. As well as Jefferson County, the California towns of Stockton and San Bernardino have recently filed for bankruptcy.
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And Detroit's fragile state—and the existence of the city's emergency manager Kevyn Orr—make the city enormously vulnerable and thus attractive to hedge funds.
Detroit was once America's fifth largest city and a thriving center of U.S. industry. Now, its population has plummeted to 700,000 from a peak of 1.8 million, a third live in poverty and basic services such as street lighting have broken down. Michigan Governor Rick Snyder appointed Orr, a corporate bankruptcy expert, in March to take over the city's finances.
Even if the city does not file for bankruptcy, its debt will likely be restructured, providing an opportunity for hedge funds to make a profit. [...]
Financial advisers, restructuring consultants and lawyers who work with the funds have told Reuters they have been fielding calls, digging through documents and even flying to Detroit as they try to pinpoint a profitable investment.
"Everyone is looking for ways into Detroit. It's new and unique," said Marti Kopacz, who founded Brant Point Advisors, which provides turnaround advice to municipal governments.
One of the normally secretive distressed debt fund managers confirmed the funds are circling the Motor City.
But what of the warnings? What does it mean to "liquidate" or "restructure" a city in the same manner you might a failed electronics company or an unprofitable factory?
According to Marti Kopacz, a financial adviser who offers guidance to municipal governments and was interviewed by Reuters for his expertise on the big-money interests circling Detroit: "I think it will be a period of time where the distressed investor community will come to an appreciation that these situations are so very, very different from a commercial bankruptcy," he said.
"Everyone points to the politics but it's even more fundamental than that. If you live in the north you have to take care of the snow and you have to have a police department and a fire department. You can't liquidate a city."
And then, of course, these questions remain: How long will "this period of time" be? And how much damage to the city might be done as the vultures gain "appreciation" whilst snacking on their scrumptious, municipal lunch?


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| 6.6°C Belfast
Newcastle defender Ryan Taylor could miss all of next season with a cruciate knee ligament injury, the club have announced.
The 28-year-old had only recently returned to training after he injured his knee last August in the Europa League qualification match against Atromitos.
The new injury blow looks set to rule Taylor out for the majority of next season and possibly the entire campaign.
Taylor had been on the sidelines for eight months after he ruptured his knee ligaments in the European fixture and Newcastle manager Alan Pardew admitted his fresh injury is a huge disappointment for both the club and the player.
He said: "Ryan has worked so hard and diligently since his injury.
"He has been a model patient and has given his all to ensure he could return to full training in the best condition possible. Clearly everyone at the club is deeply saddened by this news.
"Ryan has, and will continue to, receive the full support of everyone at Newcastle United during this difficult time for him."
Newcastle also confirmed that goalkeeper Tim Krul will undergo surgery on Monday after he dislocated his shoulder during the 3-0 Tyne-Wear defeat by Sunderland at St James' Park.
Krul, who landed awkwardly and had to be replaced early in the second half by Rob Elliot, is expected to return to training at the end of July.


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COVID-19 Update: SkinWraps is open for business. Our team is following strict social distancing and hygiene guidelines.
As a small, Australian, family owned manufacturing business, we appreciate your support during these uncertain times. Should you have any concerns or questions please feel comfortable to contact us.
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We can no longer guarantee delivery on or before December 24th for orders placed after 1pm Qld time on December 18th.


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A man who admitted to stealing jewelry and cash from an Armada Township home accused a co-defendant of targeting the victims, his own grandparents.
Garrett Savage, 22, of Almont, testified that Nicholas Fix suggested stealing cash and an estimated $100,000 in jewelry from the home of Norman and Lory Kahl in March 2013.
"The first time was joking. We talked about ideas, ways to get money, going into his grandparents house and take stuff," Savage said of an initial conversation in late December 2012 or early January 2013.
Talks got serious the following March 1 when they were joined by co-defendants defendants Frank Vallone, 26, and Kyle Preisel, 22, of Almont, he said. He called the group "best friends."
"It was a who-was-going-to-do-what kind of conversation," he said. "I was going into the house. … I was told they (his grandparents) were going to be at church" in Romeo.
Fix told him "that there was a vanity desk at the end of a hallway and in one of the drawers was money, and where jewelry boxes were in the bathroom," he said under questioning by Assistant Macomb Prosecutor Steve Fox.
Savage, donned in jail garb, testified in Macomb County Circuit Court in Mount Clemens at the trial for Fix and Vallone. Fix, 26, of Armada Township, and Vallone are both charged with second-degree home invasion, punishable by up to 20 years in prison.
He said he entered the home by breaking a side garage door with a hammer, and placed a pile of jewelry in a blue gym bag and grabbed a "big wad" of bills that turned out to be all singles, about $50.
He fled the home to a truck waiting for him on the Kahl's 34 Mile Road property driven by Vallone, he said. Fix and Preisel were in two additional vehicles serving as lookouts, he said.
The foursome within a short time drove to a jewelry store and sold the jewelry for $4,200 to a Clinton Township shop.
Lory Kahl previously told The Macomb Daily that the incident has devastated her because she was victimized by her grandson, and the jewelry was highly valued monetarily and emotionally; they included gifts from her husband and hand-me-down wedding rings from her mother and grandmother.
Savage previously pleaded guilty to third-degree home invasion, punishable by up to five years in prison, and agreed to testify on the promise he would not be charged with the more severe second-degree home invasion. He was sentenced in December to three years probation, with the first nine months in the county jail. He received 72 days of credit. He was ordered to pay $90,100 in restitution "jointly & severally" with convicted co-defendants.
Preisel also was to testify Wednesday. He pleaded guilty to a reduced charge of attempted burglary without the owner's permission. He was sentenced earlier this month to one year probation.
Vallone's attorney, Craig Tank, says that Savage acted only with Preisel and now is trying to blame Fix and Vallone.
Tank previously told The Macomb Daily that the allegations stem from long-standing disagreements and a legal dispute between the Kahls and the Fix family over a family property transaction.
Tank on Wednesday attacked Savage's credibility, noting he initially lied to a Michigan State Police detective. Savage later in the police interview revealed the plan when confronted with records of telephone calls he made to the Kahl home.
Savage said: "At that point I knew it would eventually catch up with me. I thought it would be nice to tell the truth for once."
Tank said Savage was deceitful to a friend for which he was convicted of a larceny in a separate, prior incident, an incident Savage blamed on a cocaine habit.
Tank noted that Savage admitted he told Vallone within weeks of the incident that he planned to rob Fix because of the relatively low amount of burglary bounty. Savage said he and Fix got into a fight over his comment in late March 2013.
In an unrelated matter, Fix and his mother, Dawn Fix, were given a court injunction in 2012 when they staged a mudbogging event at their parcel near 33 Mile and Rome Plank roads that township officials said violated regulations. They have also operated a haunted house on the property.
The trial in front of Judge Peter J. Maceroni is scheduled to continue Thursday.