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Friday, February 14, 2014
Conference on mHealth and cancer care
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EXPAND project: Deploying sustainable cross-border eHealth services in the EU
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Thursday, February 13, 2014
Call for Abstracts and Presenters 2014: Stanford Medicine X
Call for Abstracts and Presenters 2014: Stanford Medicine X
September 5-7, 2014 Stanford University
Stanford Medicine X invites you to submit your work to its conference, taking place at Stanford University September 5-7, 2014. Submissions will be accepted from February 1, 2014 to March 1, 2014. Please note, if you are selected as a presenter you will be required to register for the conference.
Area of Focus
Scientific research studies and scholarly practice-based work in the area of emerging information and social technologies and their effects on the field of medicine will be the primary scientific focus of the Medicine X conference. We seek submissions in a broad area of topics including:
Participatory medicine and the role of technology in empowering patient (and/or caregiver) engagement in a patient's own healthcare;
Wearable computing technologies for health (e.g. wearable sensors for tracking health, heads-up information displays)
The role of digital health technologies and their effects on patients and health care professionals;
Social/mobile technologies and their use in the areas of science, health and medicine;
Health information and content on the Internet;
Collaboration using the Internet and the use of these technologies to change health care education, delivery and practice.
We also encourage submission of work in the follow areas: emerging technologies and mental health, use of emerging technologies for or by patients with multiple chronic medical problems, digital divide in access to health information technology, engagement of patients and providers in healthcare technology.
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Video: Presentation of the Renewing Health telemedicine pilot
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ICT-enabled public sector innovation in H2020 - Video
What is our vision of the societal challenge around Public Services? Which are the funding opportunities for these topics in the recently launched Horizon 2020 framework programme?
Mechthild Rohen, Head of the Public Services Unit in DG CONNECT speaks about this. Enjoy this short video.
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Work Program Horizon 2020 on ICT
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ICT for societal challenges in H2020
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Wednesday, February 12, 2014
New connected car standards put Europe into top gear
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H2020 Info Day : Public Sector and Innovation (10/02/2014)
Find all the presentations, and the video recording, on the related website - see below.
The event was well attended and demonstrated great interest for our activities on ICT-enabled public sector innovation; over 300 participants from more than 230 organisations, representing various types of stakeholders (public administrations, universities, companies, etc.) and different countries.
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Tuesday, February 11, 2014
Call for Papers: International Digital Health and Care Congress
Call for Papers: International Digital Health and Care Congress
September 10–12, 2014 London, United Kingdom
The purpose of the International Digital Health and Care Congress is to bring together researchers, policy makers, practitioners and innovators interested in the design and application of technologies to share experiences and to showcase new ideas, new research and new innovations in digital health, mobile health, telehealth and telecare that will support improvements in the care of people with long-term conditions and other health and social care needs.
The conference committee invites submissions of abstracts for both oral and poster presentations related to the issues and themes of the congress. If you would like to present at the congress then please submit papers to one of the main topics indicated below.
Sustaining independence as people age.
Preventing and managing chronic illness effectively.
Supporting people with mental health issues.
Digitally enabling service transformation.
Innovations in technology.
Key dates
Papers must be submitted by 31 March 2014.
You wll be notified the results of your submission by 16 May 2014.
Paper types
The conference committee invites submissions of abstracts for both oral and poster presentations related to the issues and themes of the conference. Submissions should follow one of the following formats:
These presentations will provide the results, completed or in-progress, of original research projects. The material should not have been published elsewhere, except in preliminary form, and it should be ready for publication as a journal article. Papers related to PhD projects, either completed or in progress, are especially encouraged.
Projects and innovations
These presentations should focus on digital health and care in practice and should report on recent experiences in the development of new innovations. These papers should present case descriptions of health and care on the national, regional or local level.
These papers may describe any development in policy (whether governmental, organisational, or any other) that have influenced the current and future deployment of digital health and care. Policy papers that make international comparisons are especially welcomed.
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Work out to catch up
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European travellers face risks abroad – half unaware they can call "112" in emergencies in all EU countries
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Global Safer Internet Day 2014: "Let's create a Better Internet together"
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H2020 - ICT and waste - CH5
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EU support for sharing field operational test data
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Implementation of the European emergency number 112 – Results of the seventh data-gathering round
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CEO Coalition 2014: progress reports on actions to make the Internet a Better Place for Kids
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Monday, February 10, 2014
EU-project tackles under-reporting of adverse drug events
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Call for Papers for Cutter IT Journal: How IT Can Transform Healthcare
Call for Papers for Cutter IT Journal: How IT Can Transform Healthcare
Transforming healthcare is a key priority for public and private healthcare providers and governments. But the healthcare industry is facing major challenges in delivering quality healthcare services at affordable costs. How can IT transform healthcare? There has been progress in applying IT in healthcare in areas such as telemedicine, mobile health, electronic medical records (EMR) and healthcare portals. There is greater potential, however, particularly considering ongoing advances in RFID, Internet of Things (IoT), mobile devices and wireless communications, social media, nanotechnology, robotics, data analytics, context-aware systems and smart applications.
Healthcare IT is both promising and challenging to IT professionals, managers and executives. Only through the prudent design, development and implementation of healthcare IT initiatives that are aligned with healthcare procedures, practices and objectives will bring about the transformation needed for superior healthcare delivery. And there is growing concern among stakeholders over the risks of increasing reliance on IT for healthcare, including resilience, security, privacy, and availability.
In an upcoming issue of Cutter IT Journal, we'll explore the potential of healthcare IT and examine how we can address the issues and challenges that IT and the healthcare industry face in realizing the promise of IT. We are also interested in learning how the strategies and lessons learned by healthcare IT professionals could be applied by IT professionals in other industries.
We seek your perspectives and insights on healthcare IT, as feature articles, case studies, best practices and opinion pieces that address particularly the following and other related questions:
* What is the promise of emerging technologies in healthcare such as clinical decision support, visual diagnosis, RFID, IoT, biometrics, body sensors and actuators, social Media, 3D printing, context aware systems and applications, and personalized medicine?
* How is mobile technology changing healthcare? What is its impact on healthcare from the provider and community perspective?
* How can IT help reduce medical errors and improve the efficiency and effectiveness of healthcare delivery?
* How might ePrescription and EMR evolve in the near future?
* How can IT help improve safety and quality of care for patients? What are the ongoing advances in assistive technologies and systems?
* How can the strategies/lessons learned by IT professionals in the healthcare industry be applied by IT professionals in other industries?
* What are the special requirements of 'healthcare clouds' and how can clouds be better utilized for healthcare?
* How can data analytics – descriptive, prescriptive and predictive analytics – be exploited for better healthcare?
* How can IT help in integrating and coordinating fragmented and relatively uncoordinated healthcare services? How can we address the underlying issues in realizing coordinated healthcare delivery?
* What are the issues in sharing healthcare data, and how can we address them? Are there any data standards that we can embrace?
* What are the best ways to analyze large volumes of patient data to track trends, identify best practices, and determine the best treatments?
* What are the major challenges and barriers facing IT professionals and healthcare IT departments in embracing IT to advance healthcare?
* What role can a Chief Medical Information Officer (CMIO) play?
* What is your business case for transforming healthcare using IT?
* Is there any framework for formulating a healthcare IT strategy for small, medium and large healthcare establishments?
* What are the trust, security and privacy issues in healthcare IT applications, and how can they be addressed?
* How can IT, social media and mobile devices be used to empower patients and create healthcare awareness among the public? What is the potential of crowd sourcing in healthcare?
* How do developing countries embrace mobile devices and IT in innovative ways to meet their unique needs within the constraints they face?
* What have we learned from the failures — and deployment — of "healthcare.gov"? How can we do it better?
* What can IT professionals and executives in healthcare IT learn from the success of IT-enabled transformation in banking, commerce, travel/tourism, and government services sectors?
SEND US YOUR ARTICLE IDEA by 14 February 2014.
Please send your article proposal to the Guest Editor San Murugesan at smurugesan[at]cutter[dot]com, with a copy to Christine Generali at cgenerali[at]cutter[dot]com no later than 14 February and include an extended abstract (300-500 words) highlighting the scope and key contributions of the article, a short article outline showing major discussion points, and a brief bio of the author(s).
Accepted articles are due by 21 March 2014.
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EU summit on how to address chronic diseases in Europe
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epSOS at CeBIT and eHealth Forum Athens
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FOT-Net final event and first FOT-Net Data workshop
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We've seen plenty of timelines that put video game release dates in order. And recently, we've begun making timelines that put video game news in chronological order. But what about the timelines inside the games? The years over which the game's story takes place? Has anyone ever chronicled those?
Now, someone has. Alex Jaffe, specifically, who has assembled more than 1,200 games into an impressive master video game timeline that tells us, once and for all, when our favorite games took place relative to one another.
It starts waaaaay back with TMNT: Turtles In Time, which jumped the farthest back in time to 2,500,000,000 B.C. (and also gets pretty far up to the year 2100AD). Then, it travels through scads of time-travel games—Chrono Trigger doesn't even go second-farthest back—through modern times (with a lengthy digression in the early 1940s for all those WWII games) all the way up to… can you guess? The Warhammer 40,000 games, of course.
It's a Herculean undertaking that, according to Jaffe, has taken more than two years to get to this point. In fact, the timeline itself loads inconsistently—you might have to wait a bit. Apparently a timeline of this size has tested the strength of the space/timeline continuum. The data below the timeline, however, is always there, and is fun to look through even if the timeline won't load. Jaffe says he's open to feedback, corrections and additions, and that if you see anything he's missing, to please email him.
Update: Awesomely (not really), traffic has brought the timeline down for the time being. Fortunately, you can read the whole thing in PDF form here. I'll update once the timeline is back up and running.
Turtles in Time: The Video Game Chronology Project [Preceden]

subset: commoncrawl


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LONDON, UK - How likely is a new EU referendum, a "people's vote"? Public support seems to be growing, and although some claim that time has already run out, the Article 50 deadline is extendable and alleged barriers such as Electoral Commission question-testing, are more about funding.
The real obstacle is how parliament forces a referendum on a reluctant government. The UK government controls the agenda of the House of Commons, and so supporters of a new referendum need to amend a government bill relevant to Brexit. Crossbench peer John Kerr points out that since the European Union (Withdrawal) Act 2018 says that the government may not ratify a withdrawal agreement unless parliament has passed an implementation bill, such an opportunity should arise.
But there is a problem. The 2018 act imposes another condition. The government must also win a House of Commons vote on a resolution approving the withdrawal agreement and framework for future relations with the EU. If the resolution fails, the implementation bill becomes pointless and the government will presumably withdraw it. Amending the resolution to require a referendum will not work. A referendum requires a bill. The house cannot force a government to proceed with a bill, and no other Brexit-related bills are on offer.
Referendum supporters hope to negotiate around this problem by offering the government a deal: support for the resolution in exchange for a referendum. But this strategy is flawed. It assumes that given a choice between no deal and a referendum, the government would choose a referendum. But what if the government chooses no deal? This is not just a theoretical possibility. The prime minister said in Birmingham: "Leaving without a deal would be … tough at first, but the resilience and ingenuity of the British people would see us through." She claimed that a second referendum would threaten "faith in our democracy". If ministers really believe no deal is tolerable but a new referendum would be disastrous, they are unlikely to go for another vote.
The government doesn't need new legislation for a no-deal Brexit. The 2018 act already grants the necessary powers. The so-called "meaningful vote" merely requires the government to make statements and arrange debates with no legal effect.
Some call for a general election (which against an unwilling government needs a no-confidence vote). But an election will not help referendum supporters. The problem is that they need the votes of Labour MPs, either in defiance of their party's leadership or through a change in the leadership's policy. A general election makes both unlikely.
So, what can referendum supporters do? Here is one possibility.
On budget day (this year October 29), the chancellor needs the House of Commons to pass resolutions under the Provisional Collection of Taxes Act to give his tax changes temporary legal force. To maintain that temporary legal force, the government has 30 sitting days to obtain the second reading of a finance bill, at which point temporary authority stretches to seven months.
The mechanism works not only for tax changes but also for the very existence of income tax and corporation tax. These taxes are still annual, meaning authority to levy them runs out every year. Finance acts therefore always include their re-authorisation, which must take effect before their temporary authorisation expires.
How is this relevant to a referendum? The answer lies in the principle of "grievance before supply." The House of Commons is entitled to delay taxation bills when the Crown has not adequately addressed its grievances. The principle is old. In 1621, for example, the House of Commons deliberately stalled a taxation bill to squeeze concessions from the King about freedom of speech. Admittedly, the Commons itself decides, by majority, what counts as a grievance, and when it votes for a finance bill, by that very act it sets aside outstanding grievances. But where a majority insists, the principle still applies.
Two possibilities arise. MPs could move an amendment to the motion to give the Finance Bill a second reading saying that it must not be further considered until one of their grievances had been redressed – namely the grievance that a referendum had not been arranged. They could also add clauses to the bill at committee stage, making re-authorisation conditional on a referendum.
In either case, the government would face financial meltdown. Annual taxes, according to unpublished research by Will Bateman, account for 35% of tax revenues (or around £5bn a week). The government's choices would be limited: concede a referendum or resign. Ministers might briefly ponder sitting tight until exit day (one week before the end of the tax year), hoping the Commons might relent once remaining became impossible. But in the meantime, financial markets would react badly. The idea, possibly a convention, that governments incapable of obtaining supply should resign is ultimately based on the brutal realities of the bond markets.
Resignation would not itself trigger an election. A new government would emerge. But no incoming government (whether Labour or a multifarious coalition) could command the confidence of the house without supporting a referendum. And so, new government or not, a new referendum would follow.
Whether this happens depends on politics, not law. But if MPs want a referendum, they can make it happen.
(The writer David Howarth is Professor of Law and Public Policy, at the University of Cambridge).


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Wood beaten 'like a drum,' Marlins stop Braves 7-0
Alex Wood quickly looked ahead after a rare ugly loss.
"It's how you bounce back, you know?" Wood said after following up a dominant August run with the shortest start of his young career.
Wood gave up a career-high seven runs while lasting only 2 1-3 innings Sunday, and the Atlanta Braves' six-game winning streak ended with a 7-0 loss to Nathan Eovaldi and the Miami Marlins.
Eovaldi combined with Steve Cishek on an eight-hit shutout and Jeff Mathis homered and drove in three runs for Miami, which snapped its six-game losing streak.
Ed Lucas had a two-run single and Mathis added a two-run double in the Marlins' five-run third inning.
It was a rare poor outing for Wood (3-3), a rookie left-hander who was 2-0 with a 0.90 ERA in five August starts. His overall ERA climbed from 2.27 to 3.15.
"Maybe experiencing it this time will help him the next time," Braves manager Fredi Gonzalez said.
Wood, making his fourth appearance and second start of the season against the Marlins, didn't agree with the suggestion that Miami's hitters made adjustments to his pitches and delivery.
"I don't think it has anything to do with them getting a second look," Wood said. "I've thrown against some other teams more than once.
"Give them credit. They beat me like a drum today."
Veteran right-hander Freddy Garcia, called up from Triple-A Gwinnett before the game, replaced Wood in the third. Garcia, 36, threw 4 2-3 scoreless innings, allowing three hits and one walk.
"Freddy did a good job saving our bullpen," Gonzalez said.
The Braves acquired Garcia from the Orioles on Aug. 23 for cash.
"First-place team, you've got to be excited," Garcia said before the game.
Gonzalez said Garcia could also be used as a spot starter in the final month of the regular season.
Garcia is 155-106 in 16 major league seasons with Seattle, the White Sox, Philadelphia, Detroit, the Yankees and Baltimore. He was 3-5 with a 5.77 ERA in 11 games, including 10 starts, with Baltimore this season.
Eovaldi (3-5) halted Miami's skid and his personal five-game slide by earning his first win since July 12 against Washington. He gave up seven hits with two walks and six strikeouts in eight innings, his longest start of the season.
After throwing 102 pitches through eight innings, Eovaldi was not given the chance to try for his first career complete game.
"I felt great," he said. "I really wanted to go back out there."
Marlins manager Mike Redmond said it was important to give an inning to Cishek, the closer who had pitched only one inning in the last week.
"I said, `C'mon, Red!'" Eovaldi said with a laugh.
Cishek worked around a walk and a single to get the final three outs.
Eovaldi earned his first win in six career starts against Atlanta. He began the day with a 2.79 ERA against the Braves. He threw seven shutout innings, allowing only one hit, but received a no-decision in the Marlins' 1-0 win at Atlanta on Aug. 10.
Eovaldi was able to get comfortable Sunday after his teammates gave him a 7-0 lead.
"It was awesome," he said. "We blew it open in the third and I was able to relax, go right after the hitters."
Placido Polanco's single drove in Christian Yelich in the first, and Mathis homered with two outs in the second for a 2-0 lead.
The Marlins knocked Wood out of the game with five hits in the third. Donovan Solano had a run-scoring single.
Miami's Jake Marisnick threw out Paul Janish at the plate in the seventh as Janish attempted to score from second on Jose Constanza's single to center.
NOTES: Braves 3B Chris Johnson was held out of the lineup with what Gonzalez said was "a little leg issue." Johnson had a pinch-hit single in the ninth. ... Atlanta's nine-game homestand continues when LHP Paul Maholm faces Mets RHP Daisuke Matsuzaka on Monday.


text: Whether it's a portrait shot, product photo or artistic still life – it's the light that makes the picture. Unlike when you're out in the open, in a photographer's studio you have full control over the lighting. Aided by high-performance studio flash units and the proper equipment, extraordinary possibilities for creative lighting open up. Metz has the perfect solution for professionals and ambitious amateurs.


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Every now and again we wonder: "Where did that car go?" We've featured hundreds of cars over Street Machine's 35-year history, and every one of them has a story to tell. Some are still making the rounds looking just the same as they did 30 years ago, while others came and went in the blink of an eye, never to be seen again.
It's been a long time since we've seen Jamie's ute, but back when we featured it in March 2002, the car was winning just about every show it appeared in.
To say PSYCO was heavily airbrushed is something of an understatement. Every panel from front to rear was painted in Grim Reaper themes, the artwork even extending to the interior and underside. Every part of the car was either painted, chromed or polished.
The tray was filled with Alpine amps and subwoofers, and there was a Nintendo 64 and flatscreen TV to keep everyone occupied during showtime. That was pretty amazing stuff back at the turn of the millennium.
Up front there was a five-litre Holden V8 with a Vortech S-trim blower to give it some boost. It wasn't a horsepower hero, but 270hp at the treads kept it in front of day-to-day traffic.
At Summernats 15, the ute won a spot in the Top 60 hall, along with Top Murals and Top Car Display trophies, and cleaned up at just about every Auto Salon event in the country back then.
Since then the car has seen a few changes. It still has the blown five-litre, but the polished FR18 Simmons rims have been replaced by a set of large-diameter chrome wheels, and most of the original Grim Reaper airbrushing has been replaced with more modern horror movie themes.
It's not exactly subtle, but for those looking for a unique show car, the price is right. Check it and many other cool cars out on TradeUniqueCars, or follow the link directly to the VS Commodore ute on TradeUniqueCars.


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In this image of brewer's yeast (Saccharomyces cerevisiae), cells expressing the long noncoding RNA ICR1 (red) have the FLO11 gene (green) switched off. The nuclei of all the yeast cells are stained blue.
Image: Courtesy of Molecular Cell
In this image of brewer's yeast (Saccharomyces cerevisiae), cells expressing the long noncoding RNA ICR1 (red) have the FLO11 gene (green) switched off. The nuclei of all the yeast cells are stained blue.
Image: Courtesy of Molecular Cell
February 14, 2012
Tags: Fink LabRNAGenetics + Genomics
CAMBRIDGE, Mass. – Personal change can redefine or even save your life—especially if you are one of a hundred yeast cell clones clinging to the skin of a grape that falls from a sun-drenched vine into a stagnant puddle below. By altering which genes are expressed, cells with identical genomes like these yeast clones are able to survive in new environments or even perform different roles within a multicellular organism.
Changes in gene expression can occur in a multitude of ways, but a team of scientists from Whitehead Institute and other institutions has used single-cell imaging and computational approaches, along with more traditional molecular biology techniques, to demonstrate for the first time that brewer's yeast (Saccharomyces cerevisiae) cells rely on two competing long intergenic noncoding RNAs (ncRNAs) as a location-dependent switch to toggle between a sticky and a non-sticky form.
"This validates the observations from a previous paper in the Proceedings of the National Academy of Sciences (PNAS) and provides a new way of looking at the process of gene expression," says Whitehead Founding Member Gerald Fink.
The switch turns on and off the FLO11 gene, which determines whether a yeast cell exists in a free-floating form or an alternative form that sticks to other cells and colonizes substrates. In fungal pathogens such as Candida albicans, genes related to FLO11 allow the invaders to form dangerous biofilms that stick to catheters and other medical devices.
This FLO11 switch is composed of two ncRNAs encoded upstream of the FLO11 promoter, a section of DNA that acts as a docking site for transcription factors that increase or repress FLO11's expression. Although noncoding RNAs constitute the vast majority of RNAs, they do not produce proteins but instead play various mechanistic roles, including modifying chromatin, enhancing or repressing transcription, and promoting messenger RNA (mRNA) degradation, to affect a cell's gene expression.
In the earlier PNAS paper, Stacie Bumgarner, then a Fink lab graduate student, implicated two upstream ncRNAs, Interfering Crick RNA (ICR1) and Promoting Watson RNA (PWR1), in FLO11 expression. But the techniques available to her at the time lacked the resolution required to observe these ncRNAs at the level of the single cell. Most traditional molecular biology techniques that assay RNA expression generate data that provides only a glimpse of the average RNA transcript levels across a population of cells. But because populations of yeast contain some cells that are active and others that are inactive for FLO11 transcription at the same time, single-cell resolution was required to probe deeply the role of the ncRNAs ICR1 and PWR1 in regulating FLO11 expression.
In collaboration with scientists at MIT and the Broad Institute, Bumgarner recently analyzed the RNA contents of thousands of individual yeast cells to see how these two ncRNAs affect FLO11 production in each of the cells. Their work is published in the February 24 issue of the journal Molecular Cell.
"In a single cell, one can visualize an individual mRNA molecule and count the total number of each of these non-coding RNA species in every cell in the population," says Gregor Neuert, co-first-author of the Molecular Cell paper and a postdoctoral researcher in the lab of MIT physics professor Alexander van Oudenaarden. "By investigating single-cells, one gains detailed insight into gene regulation which goes beyond the average RNA expression measured on population of cells."
Instead of finding the average number of FLO11, ICR1, and PWR1 mRNAs for the entire population, Bumgarner and Neuert could visualize how much variation occurred between cells, from cells with no copies of a particular RNA to cells with multiple copies of that RNA.
Using this data, Bumgarner and colleagues formulated a model for a location-dependent switch wherein the ncRNAs use their own transcription to turn FLO11 on and off.
"It's not that the ncRNAs, as RNA products themselves, do something—it's the act of transcription in that particular site, so the site matters," says Bumgarner, a co-first-author of the Molecular Cell article. "You can kind of imagine the DNA as a railroad track, and the transcriptional machinery as a train moving down the track. The way we understand it, the train moving down the track is tossing off all of the transcription factors sitting on the DNA."
In Bumgarner's model, when ICR1 is transcribed, its transcription machinery knocks off any transcription factors from the FLO11 promoter, effectively stopping FLO11's transcription and resetting its promoter. To ultimately promote FLO11 transcription, PWR1 runs ICR1's transcription machinery off the DNA, thereby preventing ICR1 from clearing the FLO11 promoter.
"These noncoding RNAs are unusual, because to the best of our knowledge, they act only on the DNA strand that they're from," says Fink. "In many of the other systems that people have identified, the noncoding RNAs seem to act all over the place in the genome."
This work was supported by the National Institutes of Health (NIH), the National Science Foundation (NSF), and the Deutsche Forschungsgemeinschaft (DFG).
Written by Nicole Giese Rura
* * *
Gerald Fink's primary affiliation is with Whitehead Institute for Biomedical Research, where his laboratory is located and all his research is conducted. He is also a professor of biology at Massachusetts Institute of Technology.
* * *
Full Citation:
"Single-Cell Analysis Reveals that Noncoding RNAs Contribute to Clonal Heterogeneity by Modulating Transcription Factor Recruitment"
Molecular Cell, February 24, 2012.
Stacie L. Bumgarner (1,5), Gregor Neuert (2,5), Benjamin F. Voight (3,4), Anna Symbor-Nagrabska (1), Paula Grisafi (1), Alexander van Oudenaarden (2), and Gerald R. Fink (1).
1. Whitehead Institute for Biomedical Research, Nine Cambridge Center, Cambridge, MA 02142, USA
2. Department of Physics, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA
3. Broad Institute of Harvard and MIT, Seven Cambridge Center, Cambridge, MA 02142, USA
4. Department of Pharmacology, University of Pennsylvania Perelman School of Medicine, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA
5. These authors contributed equally to this work.
Whitehead Institute for Biomedical Research is a nonprofit, independent research and educational institution. Wholly independent in its governance, finances and research programs, Whitehead shares a close affiliation with Massachusetts Institute of Technology through its faculty, who hold joint MIT appointments.
Whitehead Member Gerald Fink
Photo: Chris Sanchez/Whitehead
Nicole Giese Rura
Phone: 617-258-6851
Email: firstname.lastname@example.com
Protein unmasks pathogenic fungi to activate immune response
White blood cells are picky about sugar
Scientists discover role for dueling RNAs
Whitehead Institute is a world-renowned non-profit research institution dedicated to improving human health through basic biomedical research.
Wholly independent in its governance, finances, and research programs, Whitehead shares a close affiliation with Massachusetts Institute of Technology
through its faculty, who hold joint MIT appointments.


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Pre-Retirement Planning
Retirement is an important phase of life. Careful thought and planning for retirement based on your own situation is an integral part of the retirement process. To plan and prepare for retirement, you will want to gather information - about your options, your needs, and the income that will be available to you.
We are hoping this section of the Human Resources website will give you food for thought, and provide helpful links and information about topics to consider when undertaking Pre-Retirement planning. In addition, be sure to review the web pages on Post-Retirement Benefits. Further question or concerns can be sent to firstname.lastname@example.com. If you have specific questions regarding your own eligibility and are thinking about retirement, please contact Benefits at (914) 923-2828 to make a one-on-one appointment.
Those who have retirement saving account(s) through the University should also call TIAA (1-800-842-2776) and set up a time to discuss their financial future.
Retirement decisions are among the most important you'll ever make. We urge you to consult with your financial advisor before making any final decisions. Pace University benefits staff cannot give any financial or investment advice; however, we can assist you with understanding how the Pace plans integrate with Medicare.


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Every Monday PopcornBiz applies a special formula to the top 10-grossing movies of the weekend, taking into account their staying power, budget and critic ratings to determine who really won the weekend. We call it the PopcornBiz Standings.
George Lucas' "Red Tails" opened this weekend. And if you saw Lucas parade round on "The Daily Show" and elsewhere, he'll tell you that he had an awfully hard time getting financing for his movie due to its predominantly black cast. Of course, that ignores the idea that studios would be unwilling to work with a power-mad has-been who can't write dialogue anymore, openly embraces corny tropes no one likes, and is perfectly capable of funding a $58 million production on his own using his "Star Wars" blood money. Did moviegoers vindicate Lucas in the end? Let's look at the final chart via Box Office Mojo.
1. Underworld Awakening - $25.4M
2. Red Tails - $19.1M
3. Contraband - $12.2M
4. Extremely Loud & Incredibly Close - $10.5M
5. Haywire - $9.0M
6. Beauty & The Beast 3D - $8.6M
7. Joyful Noise - $6.1M
8. Mission Impossible: Ghost Protocol - $5.5M
9. Sherlock Holmes: A Game of Shadows - $4.8M
10. The Girl With The Dragon Tattoo - $3.8M
Both "Red Tails" and "Underworld" received middling critical reception, and their grosses weren't particularly dazzling. I don't think you'll see either of them hanging around the box office for long, and our PCBS formula, knows it. REVEAL THE STANDINGS!
1. The Artist - 448
2. The Descendants - 416
3. Beauty & The Beast 3D - 119
4. Extremely Loud & Incredibly Close - 118
5. (tie) Tinker Tailor Soldier Spy - 115
5. (tie) The Iron Lady - 115
7. Contraband - 98
8. Haywire - 80
9. Red Tails - 39
10. Mission Impossible: Ghost Protocol - 37
As you can see, "Underworld" didn't even make our top 10, and "Red Tails" will likely fall out by next week. The big story here is "Extremely Loud & Incredibly Close", which finally got a wide release but failed to make a big impact at the box office or in our standings. People knew well in advance that there wasn't much Tom Hanks or Sandra Bullock here, and people hate 9/11 movies, so that may seal its fate. All the vampires and warplanes on Earth cannot stop George Clooney and Jean Dujardin.


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Adaptive Star Rain Canopy fit over the Sun Canopy and goes all the way down to the foot rest, enclosing the passenger from Rain, Hail and Wind.
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Review: 'Tomb Raider' grows up
For those of a certain age, "Tomb Raider" occupies a special place in gaming. It marked a time when the industry stepped away from the G-rated realm of Nintendo classics and awkwardly -- like a teenager learning to be cool -- stumbled into the realm of sex, violence and giant mecha robots.
The gore of "Mortal Kombat" became the killer feature everyone copied.
Visuals were measured by how realistic a character looked rather than acted. And Lara Croft seemed to be at the heart of it all. The protagonist of "Tomb Raider" mixed action gameplay and overexaggerated sex appeal to a dizzying effect.
But after 17 years later, that formula of gunplay, exploration and puzzle-solving has grown stale. A reinvention was needed, and thankfully, Crystal Dynamics had the vision to make over Croft and the franchise in the rebooted "Tomb Raider."
This isn't just prettier graphics with a few new wrinkles here and there; this is a top-to-bottom overhaul that introduces fans to a younger, more innocent Croft. She and her crewmates on the research ship Endurance are searching for the lost kingdom of Yamatai in the Pacific. Without much luck and money, they follow Croft's hunch, which brings them crashing onto a mysterious island inhabited by a strange cult.
The setup is a little "Lost" mixed with the "Hunger Games" as Croft figures out how to survive while uncovering the secrets behind the unusual locale. In the first half-hour, this grittier tone is set as Croft is kidnapped. While injured with a gaping hole in her side, she escapes her confines. Further on in the 13-hour campaign, the three pillars of the franchise -- gunplay, puzzles and exploration -- show up, but the elements are woven so tightly and unpredictably into the fabric of the world that it's almost imperceptible.
When it comes to puzzles, this "Tomb Raider" isn't as difficult as its predecessors. The game won't stump players because a new ability called Survival Instinct highlights important parts of the environment, and Croft mumbles hints to herself. All of these features guide players to a solution that at its hardest requires precise timing on jumps.
The exploration and structure of the world is more open in the reboot. Croft can traverse the island easily with her agility to run across logs and strength to hold on to ledges. As the plot develops, areas of the island become more accessible. Croft obtains new tools, and these unlock pathways that were closed off before. There's plenty of incentive to use fast travel and explore every nook and cranny for collectibles and hidden tombs. They give Croft resources to upgrade her abilities and weapons.
As important as these pillars are, combat is where most of the improvement is made. "Tomb Raider" feels modern with an automatic cover system and the freedom to handle gunfights in several ways. Players can go into a room guns a-blazing or they can be smarter and stalk cultists from behind, silently eliminating them one by one.
The choice is up to the players, but what makes the gunplay so fun is the AI. It intelligently battles players as foes deploy tactics that force Croft to move at times, mix it up with melee attacks in others or dodge and counterattack in close quarters. With cleverly designed set pieces like shantytowns or suspended ships, it's a thrill to take on an army of fanatics.
As for the plot, it's intriguing but fairly predictable. That isn't so bad because the new Croft carries so much of the game. She is the character tying "Tomb Raider" together, and seeing her transformation from fledgling archaeologist to determined explorer is a satisfying experience. Her reinvention shows the maturation of an industry and an audience: She's changed from a figure fulfilling teenage boys' fantasies to a heroine that an older generation genuinely cares about.
'Tomb Raider'
4 stars
Platform: Xbox 360, PlayStation 3, PC
Rating: Mature


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Please comment or vote on my design in Designbyhumans & Threadless
Thank U
|Prints / Wins
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16 Followers
Following 13
Please comment or vote on my design in Designbyhumans & Threadless
Hey! have a look my new artwork, wish u like…thanks!
OH WOW, feels like so very very long since i've been here, SO much AWESOMENESS, sooo little time, i only recently regained the POWER of the INTERNETS, a while ago, and i'm coming back with a BANG and a new design, which should be posted in the next few days, i really wanna get back up to date with all the CRAZY stuff thats happening, so drop me a line…soon.
hi how are you?, good? ... well just wanted to say hello and invite you to support my new design for Halloween, thanks for the care see you soon! http://www.designbyhumans.com/vote/detail/62997
My design is in the running for the 10k contest, link here
I would really appreciate the votes or at the very least some comments on my work.
Hi there! just to let you know I have new designs up! be great to hear any feedback!
best wishes,
thanks for the comments! my new design is up if you wanna check it out
can you check my design "that your children are doing" THANKSSSSS !!!
oh you're very welcome sir
God Bless
Nice win on C28.com
Hi! please check out my designs, vote and comment if you like them=)
Thanks Chris! Peace.
hey chris, thanks for the comment/vote! have you been working on any new designs?
thanks for the vote, attempts with dif colors or more color didn't have the right effect anymore
nice work chris, thank you for comments.
Thanks and sure thing! Have you checked out rediswhite.com? I could see some of your stuff having success there too, given the subject matter!
hello nice to meet you
thanks so much. Ur new design is great. Keep rockin DBH!
Nice Concept!
Thanks for the welcome! I love your work! And sure thing, you have my vote.


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Landing Gear Sept. 11
In this Friday, April 26, 2013, photo provided by the New York City Police Department, police investigate the space between a mosque and another building in New York where authorities believe a piece of landing gear belonging to one of the airliners that crashed into the World Trade Center on Sept. 11, 2001 was found. Police say the medical examiner's office will complete a health and safety evaluation to determine whether to sift the soil around the buildings for possible human remains. (AP Photo/New York City Police Department)


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TOKYO – Prospects for a comprehensive trans-Pacific trade pact appeared increasingly uncertain Tuesday as the U.S. and Japan struggle over Tokyo's commitment to keep tariffs on hundreds of farm products.
Japan's top government spokesman, Yoshihide Suga, said the two sides were still trying to bridge their differences at the last day of 12-nation talks underway in Singapore.
"Regarding those unresolved issues, I am hoping that the officials who are gathered there will work to the very end," Suga told reporters in Tokyo.
Originally, the members of the Trans-Pacific Partnership had sought to reach a deal by the end of 2013. When that failed, they set their sights on the talks this week in Singapore. Japan's Kyodo News Service reported Tuesday that another round of talks may be required to reach agreement.
The Japanese newspaper Yomiuri Shimbun said U.S. officials were considering an agreement that might initially exclude Japan after U.S. Trade Representative Michael Froman and Japan's delegate to the talks, Economy Minister Akira Amari, met twice in Singapore but failed to bridge their differences,
When Japan committed to joining the trade arrangement, it said it would insist on protecting key farm products. The Yomiuri said one option may be to eliminate tariffs on products not imported before 2010.
Differences remain between other countries on issues other than farm products, such as reform of state industries.


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NEW YORK, N.Y. – Shares of beleaguered retailer J.C. Penney rose more than 6 per cent in aftermarket trading on Thursday after billionaire financier George Soros disclosed a 7.9 per cent stake in the company.
Soros disclosed he owns about 17.4 million shares of the Plano, Texas, department store operator in a filing with the Securities and Exchange Commission. The SEC requires shareholders to disclose stakes of 5 per cent or more in a company.
Shares gained 92 cents, or 6 per cent, to $16.16 in aftermarket trading, after ending 5 cents higher at $15.24.
J.C. Penney earlier this month fired its CEO, Ron Johnson, after 17 months on the job and rehired his predecessor Mike Ullman. An ambitious turnaround plan by Johnson had backfired and caused sales to plummet.
The chain has been burning through cash. The company last week said it would draw $850 million from its $1.85 billion revolving credit line to pay for replenishing inventory, particularly for its overhauled home area.
The stake makes Soros the fourth largest shareholder in J.C. Penney. The top shareholder is activist investor William Ackman's Pershing Square Capital, with a 17.8 per cent stake.


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In this episode of the Motivation Plus Marketing podcast, John Di Lemme talks about this Mind Blowing Olympian Day. Get an Olympian Mindset!
FREE Marketing Words Book! Yes, Absolutely FREE!
*57* Must Use Words in Every Piece of Marketing You Do for Your Book (Click Here) Grab a hold of your FREE copy of this book that has changed lives worldwide. PLUS receive the audio book as a Bonus!


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Playing junior with his hometown Rangers, Stevens and his Kitchener teammates were the Memorial Cup champions in 1982. That summer, Scott was the first round selection of the Washington Capitals, the fifth overall pick in the NHL's Entry Draft.
Debuting that fall with the Capitals, the big, sturdy rearguard earned a regular spot with Washington, and so impressed that pundits that he was selected to the NHL's All-Rookie Team.
Through eight seasons, including a selection to the First All-Star Team in 1987-88, Stevens helped turn around the floundering franchise. His fierce confidence on the blueline made him a favourite with both his teammates and the fans. So, it came as quite a shock when Scott signed as a free agent with the St. Louis Blues prior to the 1990-91 season. With Brett Hull on the wing and Curtis Joseph in net, the future looked bright for Stevens and the Blues.
Then, to Scott's surprise, in 1991-92, after only one season with St. Louis, he was transferred to the New Jersey Devils in exchange for Brendan Shanahan as part of a high-profile arbitration case. In New Jersey he was made team captain. That first season in New Jersey, Scott was elected to the NHL's Second All-Star Team. In 1993-94, he was named to the First All-Star Team.
The captain took on an increased role as inspirational leader of the Devils, who won the Stanley Cup in 1995. The Devils players and fans were galvanized by Stevens' thundering hits on opponents; key psychological elements in the victory. New Jersey won the Stanley Cup again in 2000 and 2003. While Stevens had been a star in the NHL for many years, including All-Star nods in 1996-97 and 2000-01, the 2000 playoffs must be considered Scott's defining moment. His thunderous checks, most notably on Eric Lindros in the semifinals, both inspired and dominated the post-season, and when his Devils won the Cup there was no question that he would be chosen winner of the Conn Smythe Trophy as the most valuable player in the post-season.
Stevens again hoisted the Stanley Cup in 2003, and again was noted for delivering gigantic bodychecks. But although he had gained a reputation as an NHL Iron Man, having played 22 seasons in the NHL and regularly been among the leaders in games played, coming off his third Stanley Cup victory, Stevens' hard-nosed style caught up with him. He missed the majority of the 2003-04 season with post-concussion syndrome. On September 6, 2005, Scott Stevens was forced to retire.
In 1635 regular season games, Stevens collected 196 goals and 712 assists for 908 points, impressive for a defensive specialist. Equally impressive were the 2785 penalty minutes Scott earned - no quarter asked, no quarter given.
Outside his NHL career, Stevens also represented Canada on the international stage at the World Championships in 1983, 1985, 1987 and 1989, the Canada Cup in 1991 and the World Cup of Hockey in 1996. In 1998, Scott was selected as part of Team Canada competing in the Winter Olympics in Nagano, Japan.
Following his retirement as a player, Scott returned to New Jersey as an assistant coach beginning with the 2012-13 NHL season, and served in that capacity for two seasons. Three months after stepping down, Stevens returned as co-head coach with Adam Oates. Prior to the 2016-17 season, Stevens was hired as an assistant coach by the Minnesota Wild, but remained for just that season.
A dominant figure on the blueline of any team with which he played, Scott Stevens will be remembered with great enthusiasm as a great captain, inspiring teammate, outstanding bodychecker and, most important of all, a champion.
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Portugese Designer, G-Shock Fan and forum memebr Miguel Ayako has followed his awesome line of G-Shock concept designs with a collaboration with Slingshox.
Miguel Ayako is an amazing artist from Portugal. I am inspired by his artistic style and understanding of the unique space where art and fashion collide, says Brett Pulli, SlingShoxs Founder and CEO. Ayako has a passion for G-Shock watches and street culture. It is a great match for the SlingShox brand. The product really speaks for itself. SlingShox is launching the first ever watchband accessory that transforms a G-Shock into a glow-in-the-dark work of art. Its an amazing piece to add to any G-Shock collection. The fact that we limited the production makes it extremely desirable. SlingShox will sell out of this product in a very short time after the live release.
The Miguel Ayako SlingShox will be available exclusively at www.theslingshox.com on Friday, May 10, @ 4:20pm EST. The collaboration is a limited-edition band and only 250 will be available for sale. The price is only $40 on the SlingShox website.


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McDonald's has the Shamrock Milkshake and now, you can have a Shamrock Milkshake Cupcake. Thanks to Better Homes and Gardens, this minty cake will have you smiling with each bite. I had to tweak a few parts to make it gluten free and dairy free (which unfortunately a Shamrock Milkshake is not) But it's ok! This is going to be delicious!
Shamrock Milkshake Cupcakes
- 4 egg whites
- 2 cups all-purpose gluten free flour (Better Batter or Bob's Red Mill or whatever you prefer – add xanthan gum accordingly if using a mix that does not have xanthan gum in it already)
- 1 teaspoon baking powder
- 1/2 teaspoon baking soda
- 1/2 teaspoon salt
- 1 cup buttermilk or buttermilk substitute: (make the substitute and then only use 1 cup of it)
- 1 1/2 cups coconut or rice milk
- 1/2 or 2/3 cup sugar
- 3 tablespoons vegan butter (Earth Balance)
- 1 teaspoon pure vanilla extract
- 1/4 cup green creme de menthe**
- 1/2 cup vegan shortening (Earth Balance)
- 1 3/4 cups sugar
- 1 teaspoon pure vanilla extract
- 1 recipe White Chocolate Frosting
- Green food coloring
- Allow egg whites to stand at room temperature for 30 minutes. Meanwhile, line twenty to twenty-two 2-1/2-inch muffin cups tins with festive paper liners. In a medium bowl stir together flour, baking powder, baking soda, and salt. In a 2-cup glass measuring cup combine the buttermilk and the creme de menthe. Set aside.
- Preheat oven to 350ºF. In a large mixing bowl beat shortening with an electric mixer on medium to high speed for 30 seconds. Gradually add sugar, about 1/4 cup at a time, beating on medium speed until light and fluffy. Beat in vanilla. Add egg whites, one at a time, beating well after each addition. Alternately add flour mixture and buttermilk mixture to shortening mixture, beating on low speed after each addition just until mixture is combined.
- Spoon batter into prepared muffin tins, filling each about two-thirds full. Use the back of a spoon to smooth out batter in cups.
- Bake for 15 to 18 minutes or until tops spring back when lightly touched. Cool cupcakes in muffin cups on wire racks for 5 minutes. Remove cupcakes from muffin cups. Cool completely on wire racks.
- Time to make your frosting while the cupcakes cool.
White Chocolate Frosting
- 1 cup vegan butter, softened (Earth Balance)
- 6 ounces white baking chocolate with cocoa butter, chopped
- 1/3 cup rice whipping cream
- 1 1/2 – 2 cups powdered sugar
- Place white baking chocolate in a large mixing bowl; set aside. In a small saucepan heat whipping cream just until simmering. Pour over white baking chocolate; let stand, without stirring, for 5 minutes. Stir until smooth; let stand for 15 minutes.
- Gradually beat butter into melted white chocolate mixture with an electric mixer on medium to high speed, beating until combined. Gradually beat in powdered sugar until frosting reaches piping or spreading consistency
- Divide frosting between two bowls. Tint one portion with green food coloring. Spoon each frosting into a pastry bag fitted with a large star tip. Pipe white and green frostings onto tops of completely cooled cupcakes to resemble four-leaf clovers or whatever decoration you'd like!


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Saturday, August 29, 2009
Out and about the California streets
Two drawings form the last couple of years, sketches taken while out there with my friends.
The street scene done while waiting for some yummy italian meal to be brought to our table on a day out in Palm Springs with Patrick and Nina (Btw, happy Birthday Patrick!), the girl sketch is one of the many we did with the sketchclub guys during the Sony days. Good moments indeed...
Posted by Marcos Mateu at 7:17 AM 38 comments:
Sunday, August 02, 2009
More things , works, haunting me from the past... from the adventurous days of the woman that was not Roberta Alvarez.
The funny face is a random sketch, also from a forgotten folder...
The funny face is a random sketch, also from a forgotten folder...
Posted by Marcos Mateu at 10:37 AM 24 comments:
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To be fair, it might not be for Memorial Day specifically, but you know they're psyched for this four-day weekend. Also note the lack of a soundtrack, which only furthers the high drama. One time, in middle school I fought my sister just like this, and she scratched my cornea, and for days I had to wear an eyepatch like an awkward 14-year-old pirate. YOLO?
Who will win? Why are there lambs in the house? As Gene Wilder said in Willy Wonka And The Bad Acid Trip, "There's no earthly way of knowing."
[via Tastefully Offensive]


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WBUR News
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Pitching Lifts Twins Over Sox
The Minnesota Twins aren't taking any chances with Scott Diamond's surgically repaired left elbow.
On Tuesday night, he didn't give the Boston Red Sox many.
Diamond allowed three hits in seven shutout innings, Ryan Doumit hit his first homer of the season and the Twins beat the Red Sox 6-1.
Diamond said he still felt strong when he left the game but understands the cautious approach less than five months after the operation.
"This is only my (fifth) start after surgery," he said, "so I feel it was a smart play."
Diamond (3-2) is having a strong season after a rookie year in which he went 12-7 with a 3.54 ERA. He's allowed three or fewer runs in four of his five outings.
On Tuesday, he retired his last 15 batters, didn't allow a runner past second base, struck out two and walked none.
"Diamond was great for us," Twins manager Ron Gardenhire said, but "coming off the elbow thing, we're really a little leery of" letting him throw too many pitches.
He threw 96 against Boston after tossing 78, 97, 97 and 88 in his other starts.
"Everything's kind of been getting back in sync," Diamond said. "That's the focus now, just continue to build and get stronger."
His approach to the game hasn't changed even if he's not pitching as long as he'd like. He still prepares intensely and throws aggressively.
"I might as well have taken a rocking chair out there. He makes it real easy," Doumit, his catcher, said. "He's one of the most prepared pitchers I've ever been around."
David Ortiz got one of the hits off Diamond, a leadoff single in the second that stretched his hitting streak to 27 games, a run that began before he sustained a season-ending injury in August. He has at least one hit in all 15 games he's played this season.
Ryan Dempster (2-3) pitched well for Boston and left trailing 2-0 in the top of the eighth after third baseman Pedro Ciriaco made errors on the first two batters, putting runners at first and third. That led to four runs, three of them unearned, as the Twins took a 6-0 lead.
The Red Sox entered the game with the best record in the majors, but have scored just 11 runs while losing four of their past five games.
They also lost two players after they collided chasing a foul pop by Chris Parmelee in the fifth near the low wall about halfway between home plate and third base.
Third baseman Will Middlebrooks caught it, but catcher David Ross slid into him, forcing his back to hit the wall. Ross left later in the fifth with a left thigh contusion and Middlebrooks was replaced by Ciriaco to start the seventh because of pain in his right side.
Ross is listed day to day, while Middlebrooks said he could have stayed in the game but will have X-rays and CT scans, Boston manager John Farrell said.
Josh Roenicke worked the last two innings, allowing Jarrod Saltalamacchia's fourth homer in the ninth.
The Twins took a 1-0 lead in the fifth on a leadoff double by Doumit and an RBI single through a drawn-in infield by Wilkin Ramirez. They made it 2-0 on Doumit's homer with one out in the seventh. It was upheld on video review after umpires ruled the ball had cleared the home run line at the top of the left field wall before a fan caught it.
"I made two mistakes and (Doumit) took advantage of both of them," Dempster said. "The way Diamond was throwing the ball and keeping us in check, you knew that eventually one run would be maybe one run too many."
It all unraveled for the Red Sox in the top of the eighth with three errors, a walk and three hits.
Ciriaco bobbled leadoff hitter Brian Dozier's grounder for his first error. The next batter, Jamey Carroll, hit the ball to the left of Ciriaco, who couldn't come up with it for his second error as Dozier took third.
"That was uncharacteristic of Pedro," Farrell said. "He has shown to be a very dependable defender."
Said Ciriaco: "I just missed those two balls. I've just got to be more ready and next time make those plays."
Craig Breslow then replaced Dempster and failed to retire any of the four batters he faced. Joe Mauer doubled in one run, Josh Willingham walked to load the bases and Justin Morneau and Trevor Plouffe followed with RBI singles.
Alex Wilson relieved Breslow and Doumit grounded to first baseman Mike Napoli, who threw home for the force out - the first of the inning. Saltalamacchia tried to double-up Doumit, but his throw was low for an error and Napoli's return throw was too late to get Morneau.
NOTES: Patty Campbell, mother of Krystle Campbell, who died in the Boston Marathon bombings, threw out a ceremonial first pitch. ... With two singles, Morneau has 1,219 in his career, passing Torii Hunter's 1,218 for eighth most in Twins history. ... Pedro Hernandez (1-0) pitches for Minnesota against Allen Webster (0-0) on Wednesday night in the third game of the four-game series ... The Red Sox placed Joel Hanrahan on the disabled list with a strained right forearm one day after their other closer, Andrew Bailey, went on the DL with a strained right biceps. Farrell said Junichi Tazawa would have filled that role if needed. ... Ortiz's streak is the longest by a Red Sox player since Manny Ramirez had a 27-game streak from July 15 to Aug. 1, 2006.
This program aired on May 8, 2013. The audio for this program is not available.
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Thermoelectric cooling module is eco-friendly and requires no refrigerating fluid. The thermoelectric cooling module is slim and compact in size, light-weight, make no noise and does not vibrate. Make sure whatever you need to be hot or cold is kept at the perfect temperature with this thermoelectric cooling module.
Thermoelectric Cooling Module
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Compact size and light-weight
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Cooling or heating by changing current direction
Model: TES107103
Max. Current: 3A
Max. Temperature Difference: 67 deg C
Max. Voltage: 1.9V
Max. Refrigerating Power: 2.14W
Couples: 17
Size (L x W): Approx. 23 x 23 mm
Cable Length: Between 11 and 13 cm
Color: White
Wiring: Red line for anode, black line for cathode.
Package Includes:
1 x Thermoelectric Cooler


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Pizza Obsessives: Jim Gerhold (aka 'JimmyG')
Slice interviews with folks who are mad about pizza.
This week's obsessive is becoming quite the regular on My Pie Monday. Let's get to know our fellow pie enthusiast JimmyG a little better with a warm, er, I mean 'hot seat' welcome.—MS
Name: Jim Gerhold
Location: Lawrence, KS
What type of pizza do you prefer?
My favorite is a regular New York pizza pie. But I also enjoy a good Neapolitan pizza, or what I call a Sicilia style pizza: semolina or a semolina mix replacing the bread or 00 flour; a young and melt-able sheep's milk cheese replacing the mozzarella.
The Pizza Cognition Theory states that "the first slice of pizza a child sees and tastes ... becomes, for him, pizza." Do you remember your first slice? Where was it from, is the place still around, and if so, does it hold up? On that note, has your taste in pizza evolved over time?
The first slice I remember was when I was around the ages of four or five. My grandfather took me to a joint called Nick's Pizza located off 25A between Smithtown and St. James, NY. While I am certain I had eaten Nick's pizza before, this was the first time I got to ride along, order the pie, and bring it home to our family and friends. I am not sure why the experience thrilled me so much, but I remember that I was a proud young man walking in the door with that pie.
At the time, I thought Nick's was the greatest pizza in the world and rightfully so; the owner had been throwing pies and perfecting his craft at the same location since the 60s. The pizzas at Nick's were excellent even as I got older. About ten years ago the quality started going downhill. I was told they changed hands within the family or something; that's not always a good thing for pizza.
You hinted at being of Sicilian descent in this week's My Pie Monday. Is that so? Are there any Sicilian styles that need to take hold in the States that haven't yet?
Yes, I am of Sicilian decent. My mother's side of the family originates from a town northwest of the port city Catania called Paterno. I would spend a couple weeks over there each year when I was younger.
Most of my experience comes from eating, rather than watching Sicilian breads being made. I do think the flat breads and stuffed breads endemic to Sicily (e.g., sfincione, rianata, sciaciata and mpanata) have yet to be exploited by pizza makers here in the States (and I do mean exploited). Historically, most of the breads produced on the island were made with semolina. The sweet and nutty flavors coming from this grain are far superior to anything that can be mustered by white 00 flour, all-purpose, or bread flour. The flavor from the Rianata crust alone, which I made last week, blew my mind.
However, I see some of the reasons why this Sicilia style has not caught on. For one thing, Semolina is very difficult to work with, as I am finding out. It has a higher protein content then most other grains, making it difficult to kneed, and depending on who is milling the grain, consistency can be an issue. In addition, many of the traditional ingredients used for toppings or fillings do not appeal to many Americans. The use of anchovies, sardines, eggplant, cauliflower, raisins, fennel and sheep's milk cheeses are a little too foreign for most American palettes. Nonetheless, next time you are making pizza replace half the flour with semolina and the mozzerella with a young Pecorino cheese. Then tell me who make a more flavorful pie, Campania or Sicilia.
What's your favorite topping or topping combination?
It needs to be simple, three or less ingredients. If I had to choose, it would most likely be sausage and mushroom, but I am just as happy, if not more, with a regular cheese slice.
Where do you go for pizza in your area?
Sadly, my pizza adventures are limited to my home mostly. I hate to sound like a snob, but I really have not found a great pizza joint in my area. The Midwestern pizzas are a little too heavy and greasy for my pallet. In addition, when you learn how to throw a better pie at home than what is being produced by your run-of-the-mill pizzeria, eating out ,more often than not, becomes an exercise in disappointment.
We've had a good preview of your home pizza-making on My Pie Monday. How often do you make pizza, and what recipes and methods do you follow?
I make pizza at home about once a week. Most of the time I am just making pizza for the pleasure of eating pizza, or maybe trying out a new topping or reproducing an old favorite. The dough recipe I use is a fairly standard NY dough recipe, which I call my "control" (explanation to follow).
Sometimes though, a geekier side of me emerges. By day I masquerade as a Nutritional Scientist/Biological Anthropologist; therefore, from time to time, the need for a hypothesis-driven science experiment will emerge. Typically when I decide to conduct an experiment I will make two or three recipes at once—a "control" or a fail-proof recipe and an experimental to compare my manipulation(s) to. Then for my experiment, I may formulate a hypothesis that I want tested: e.g. that sugar content does not affect crust browning given a 2-day fermentation period. The control dough recipe for my NY style dough in a baker's percentage is approximately: 100% bread flour; 64% water; 1.8 % salt; 2% olive oil; 0.4% instant dry yeast; and no sugar (a largely unnecessary additive). From there I create two "experimental" doughs. To one dough I might add in 1% sugar and to another dough 4% sugar. This way I am able to deduce what affect sugar content has on flavor, texture and/or dough performance by comparing the experimental to the control. All of which helps me to learn a little more about the physical properties of each ingredient going into my crust and how they interact with each other.
For making pizza, all I have is a baking stone that I preheat for an hour in my gas oven at 550 F. I really haven't had many complaints with the method so I have never innovated it. I guess if I tried a new cooking method it would the cast-iron broiler method or cast-iron on a kettle grill; given I that could find a flat slab of cast-iron I could use my pizza peel on (here's hoping @dmc).
But like I said at above, I mostly make pizza for the sake of eating pizza.
Well, scientists can be real "control" freaks (ba dum dum). So what do you think should NEVER go on a pizza?
I don't place blame on any one topping alone. After all, the topping didn't choose to go on that pizza. In my view, the success or failure of any pizza lies with the person creating the pie. It comes down to choice, and whether someone knows how to execute their idea and how well they understand the products they are using. The exceptions being pineapple, corn, mayo, and barbecue sauce.
Um, I just imagined all those together and it wasn't pretty. Have you ever eaten a topping monster like that?
I let a friend of mine talk me into eating a sushi pizza once. I will never speak of that horror again.
It would definitely be disgusting either way, and sorry to make you go into more detail, but do you mean raw fish on pizza crust or a wheel of rice with fish toppings meant to resemble a pizza? I know it may be tough to conjure those memories, but I need to know more.
Okay Meredith, to satisfy your curiosity I will relive the horror. This bastardization of pizza occurred about five years ago at a conference I was attending in Toronto. The name of the restaurant escapes me, but it was a sushi restaurant. Somehow a friend of mine talked me into splitting a sushi pizza as an appetizer. The grossness of the experience is best summed up by emulating a Ruth Bourdain style limerick: Edgy sushi pizza; looming storm. Warm cheese oozing on my rice biscuit, melting sriracha mayo creaming my fingers, splash of soy. Ripe smelling raw tuna, hot stuff. Barf bag comforting my quivering lips. (Adapted from Ruth Reichl's July 8th Twitter feed.)
That's pretty dark, but I'm not really sorry I asked—especially since I got a limerick out of you! But I think it's best to bury that experience for good. Let's move along to a happier time. What's the farthest you've traveled for pizza?
On purpose... just for pizza? That would be when I fly back to Long Island. I carry the phone number of my favorite pizzeria (Patio Pizza) in my cell phone just for the occasion. That way when I am exiting MacArthur Airport I can call them up, order my pie, and they will just have it out of the oven and ready to go for me as welcome back to NY.
Speaking of home, what do your friends and family think of your pizza madness?
They think it is great. I am always making too much so it turns into free pizza and BYOB night at Jim's house, who is going to turn that down?
Anything else you'd like to get off your chest?
That's a loaded question. I know I am going to catch hell for saying this but I do not like the idea of endless hybrid pizzas, for example: sushi pizza, curry pizza, Thai pizza, cheesesteak pizza, taco pizza, cheeseburger pizza, gluten-free pizza, etc. In my opinion people are getting too liberal with their definition of what constitutes pizza—the crust, the sauce, and the toppings. It detracts from the elegant simplicity of what a true pizza is meant to be. Take for example the cheeseburger pizza. I love both burgers and pizza, passionately. However, when they are combined, they're not nearly as good as the foods by themselves. The ingredients aren't to blame, it just takes separate cooking techniques to produce the distinct flavors and textures we associate with each. The almost predictable ending to this chimera is a pizza that fails to deliver on either front. That doesn't mean I am against someone trying to make it happen and I will gladly eat my words (and their pizza) if their endeavor succeeds.
Who would you like to see interviewed next?
I personally would like to see the Tom "The Dough Doctor" Lehmann interviewed. There has got to be a few good tips and interesting stories about the industry coming from him.
I think Slice is going to need to get a pizza celebrity interview column going soon and I'll put the Doc on the top of the list. Thanks for taking the time to tell us a little about yourself, Jim! Keep Slicing it up!


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For years, the success of many fitness facilities depended upon their ability to offer all the bells and whistles. This approach made it difficult for smaller independent club operators to compete with larger, better-equipped, multi-location operators. Having seen the writing on the wall, industry watchers predicted that large club operators such as Bally Total Fitness, 24 Hour Fitness, Gold's Gym and Town Sports International would gain a stranglehold on the industry. But, much like the Y2K phenomena, this prediction has come and gone without much fanfare. Instead, during the last few years, we have actually seen a massive rise in the small club category. Today, smaller clubs represent about 50 percent of the commercial fitness club market. How did this happen?
The small clubs' comeback occurred due to the onslaught of the fitness franchiser who chose to address the needs of the most dominant market force, the Baby Boomer. All around the country, express clubs, women-only clubs, Pilates studios, yoga studios and personal training studios opened without all the bells and whistles, but they were successful because they addressed members' needs.
So what's on the horizon? Will the large club chains return to dominate the industry landscape? Will the rash of fitness franchises continue?
Most of the changes above occurred because of the Baby Boomers. The question now is: as the Baby Boomers turn 61, what are their needs going to be? A good place to start is with a small three-club operation called Nifty after Fifty. This California-based group is owned by Dr. Sheldon Zinberg. Upon entering his club in Whittaker, CA, I noticed that his facility has no loud music, is spotless, and its reception area looks more like a clinic's reception area than a club's. When I walked into the fitness area, I was initially underwhelmed because it's just a square room with strength equipment along the side of two walls, cardio equipment along a third wall and physical therapy beds along the fourth wall. The center of the room is left open for classes and events. But, it quickly became apparent that Nifty after Fifty was a cross between a physical therapy clinic and a small fitness center.
What matters at Nifty after Fifty is not the sizzle but the clients' experience. It offers therapy for those who need it, and, for those in therapy, the transition to a fitness program is made easy. The club also offers a cognitive training center and a driving simulator for those who want to keep their driving skills and reaction time up to speed, so to say. This organization knows what their members want and gives it to them, just like the franchisors did with the time-based clubs.
So what does this mean for 2007 and beyond? The fitness market will always have large clubs, small clubs, multi-location operators, independent operators, specialized clubs, studios and big-box centers. Why? Because a client is out there for all of them. But as the population continues to age, we will see more and more clubs like Nifty after Fifty, GreatLife Center, HealthFit for Women & Seniors, Center for Active Aging & Healthy Living and Peoplefit.
Over the past few years, we have seen the industry shift, stall and churn with the typical bells-and-whistles model. During this time, a subset of our industry rose from the ashes by addressing the largest segment of the population's needs with tools and facilities that seem underwhelming. Now they make up half the industry. This demographic opportunity will continue for years to come, but the needs will be different as will the tools needed to properly serve the market. How you address these needs may dictate whether your business sinks or swims in the future.
Colin Milner is chief executive officer of the International Council on Active Aging™. An award-winning writer, Milner has authored more than 100 articles on aging-related issues. He can be reached at [email protected].


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Dear Florida,
There are a lot of things I love about you. The winter weather. The splendor of your marshes and coastlines. The diversity of culture.
But I'll be honest. When it comes to education, you pretty much blow chunks.
In our schools, the best things happen in spite of Tallahassee, not because of it.
See, I love my son's world-history teacher. I trust my daughter's algebra teacher.
I neither love nor trust you.
Not when it comes to education, anyway.
With you, kids are treated like political props.
That would be bad enough. But right now, you're not even sure which political games you want to play with them.
You love the FCAT. You hate the FCAT.
You want Common Core. You don't want Common Core.
You want tough school grades ... until you decide to inflate them.
Please. Just. Stop.
It doesn't have to be as complicated — or political — as you make it.
The latest news has Gov. Rick Scott backtracking on some of his commitment to the state's new education standards, called Common Core, specifically with regard to testing.
This was partly in response to people who believe Common Core is some sort of United Nations takeover of public schools.
And this is the problem, Florida. Too often, you listen to the folks wearing tinfoil hats. These people need therapy couches, not seats at the curriculum table.
I don't know if Common Core is a panacea. Probably not.
But I'll tell you what I do like about it: It's a nationwide endeavor, created and adopted by governors and educators in a majority of other states. And frankly, I trust other states more than I trust you.
You, Florida, have treated my kids like a punching bag.
You have cut art classes. You have cut science curriculum. You have cut music and sports.
You cut many of the things that make kids well-rounded human beings.
See, my kids aren't widgets. They are creative, curious creatures. Their minds are like sponges.
They want to learn. I want them to learn.
About math and science. About reading and arts.
I want them to read Dickens and Bradbury. I want them to understand terminal velocity and the Electoral College. I want them to know how to multiply compound fractions and understand culture in the Middle East.
Yes, I want them to take tests — even standardized tests. Like I did when I was a kid. I just don't want those tests to be their obsession.
Many of my kids' teachers want and teach the same things. But they do so in spite of your bureaucratic baloney.
I want decisions about education made by people who teach for a living — not those who politic for one.
I am sick of politicians using my kids to pander to political causes, ideological groups and testing companies that write campaign checks.
I'm sick of legislators who home-school or privately educate their kids blustering about the sanctions they want to impose on other people's children.
It never seems to dawn on them that private schools are appealing, in part, because they aren't subjected to the same convoluted, top-down micromanagement imposed on public schools.
Here's the thing: Florida, we've had about a decade's worth of your "reform" — and it's a failure.
Not by my standards — by yours.
You insisted on making the world revolve around FCAT and then grading schools on those test scores. Yet we now have record numbers of F-rated campuses.
Even worse, that's with grade inflation, because you knew accurate scores would look even worse.
That's right. You inflated your own lousy grades — and then had the gall to lecture me and my kids about accountability.
Much of this has been a Republican-led war on education. But now it's Republicans at war with one another. Jeb Bush wants Common Core and associated testing standards. Rick Scott used to agree … until the tea party told him not to.
I think I'm ready to side with Jeb — not because I agree with everything he does, but because he has widespread support, from the national teachers association, President Obama and governors in both parties.
Opponents of Common Core include Glenn Beck and a liberal splinter group of the teacher's union.
I think I'd rather hang with the first guys.
Still, I'll still be watching closely. If Common Core — which attempts to measure deeper levels of problem-solving and comprehension — doesn't deliver as promised, I'll object. If the testing that accompanies it is suspect, I'll speak up.
Ideally, I think decisions should be made at the local level by trained educators.
But for now, I'm ready for this state to join the big kids.
Basically, Florida, I've had enough of your "reform."
It's now time for you to reform — and put kids and teachers ahead of politics and talking points.
firstname.lastname@example.com or 407-420-6141


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Real World article
(written from a Production point of view)
(written from a Production point of view)
David F. Tepool (20 October 1954 – 28 May 2009; age 54) was a game designer that was one of the co-designers of the FASA Star Trek: The Role Playing Game system in the 1980s, along with Guy W. McLimore, Jr. and Greg K. Poehlein. He was also the creator of the Star Trek: Starship Tactical Combat Simulator.
He retired from game design at the same time that McLimore and Poehlein created the MicroTactix company, but in the mid-2000s, ran Olde Rivertowne Miniatures, a mail-order firm in Indiana.
During the 1980s, he worked primarily for FASA, but also did some work for TSR, including a collaboration with McLimore and Poehlein on a portion of the Castle Greyhawk set.
Community content is available under CC-BY-NC unless otherwise noted.


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Doing business guide Iraq has been saved
Doing business guide Iraq
Understanding Iraq's tax position
The "Doing business guide – understanding Iraq's tax position" is aimed to guide businesses who are looking to invest in Iraq, or those who have been present there for some time through the complex and ever evolving jurisdiction.
The report provides businesses with the main tax aspects for doing business in Iraq.
Following are the topics covered:
- Indicators for starting a business in Iraq
- Procedures for starting a business in Iraq
- Entering the market
- Taxation in Iraq
- Deloitte in Iraq – how can you benefit?
Iraq Tax practice
Deloitte in Iraq has long recognized that the complexity of modern taxation matters makes it a subject in itself. All tax affairs of Deloitte clients in Iraq are therefore handled by a partner, principal and supported by a team of dedicated tax staff, available to serve clients locally and across borders.
Your Deloitte Iraq tax services team:
Ayad Mirza
Alex Law
Brisida Acar
Atheer Aljuboory


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Volunteers working to renovate Torrington's historic Skee's Diner
TORRINGTON >> The process of restoring Skee's Diner and finding its permanent location is underway.
President and CEO of Northwest Connecticut's Chamber of Commerce JoAnn Ryan wouldn't reveal the current whereabouts of the beloved eatery that was moved from the city in April, but she said that work to repair the diner is all being done indoors.
The chamber donated the diner, which is listed on the National Register of Historical Places, earlier in the year to the Torrington Historic Preservation Trust.
"That organization did a tremendous amount of work to move it to its current location," Ryan said on Monday. "It's indoors, and it's being restored, completely renovated."
The trust took ownership of the diner in March, and Ed Cook, trust president, said the diner is doing very well. He said that a full assessment of what the diner requires for repairs and renovations will be complete sometime by late August or early September. The assessment will serve as a checklist that also organizes and assesses the items and parts the 29,000-pound diner will require to function properly.
Cook also said he couldn't reveal the location of the diner, but said that the trust is getting "pretty close" to deciding a permanent location for the diner. He said the location will be in Torrington.
"Our goal as a group is to relocate Skee's in Torrington and use it as a full-fledged restaurant," Cook said. "We want it to be a restaurant and diner, just as everyone remembers."
All work for the restoration is being completed by members and volunteers of the Trust.
"We've been working on it for the last couple of months, weekends mostly," Cook said. He said that repairing the diner has involved the reexamination of the under-structure of the building, including the framing and support systems, to asses the amount of renovation required.
"Once we moved it, we needed to disassemble it, get the skin off," Cook said.
Cook said it's hard to say when the entire project--restoring the diner and moving it back to Torrington and opening up the diner--will be complete.
Fundraising efforts to help with the rebuilding are already under way.
A fundraising dance is scheduled for Sept. 28, Cook said, at P-Sam's Bar & Grill in Torrington. He said the dance will feature a live band.
Other fundrasing events are also in the works. A website, skeesdiner.org, was launched in April when the diner was moved from Torrington and features a "Donate" button, which Cook said has helped raise money. In all, Cook said, about $1,000 has been donated since the diner moved. Donations have been made from people as far off as Oklahoma.
"We are just getting started," Cook said. "We are obviously going to need much more than that."
Cook said the trust will have a booth every Thursday at the Main Street Market Place in downtown, which begins on July 11. Contractors have also contacted Cook pledging assistance free of charge, he said.
Residents and well-wishers eager to learn more about the restoration process can follow the progress at skeesdiner.weebly.com, a website created by the trust to chronicle the restoration. The site features photos as well.
Reach Esteban L. Hernandez at (860) 489-3121, ext. 328.


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The complete list of links to articles and blogs on the calendar.
PDF copy of One Change A Day throughout the year.
WordPress annual report – One Change A Day statistics
Thank you reading this blog, also for all the comments and likes throughout 2012:
Coach Carole, Colonialist , Juandomingofarnos , VanessaVaile, George Veletsianos, Tom Hogers, Weiterbildungsblog, plerudulier, R Lewis Cordell, Amber Thomas, Leslie Poston, AnitaAnswers, Josh, John Mak, BrainySmurf, Liz Renshaw, Jaapsoft, JuergenAlbers, Glory Bea, Jonas Backelin, Josh Chalmers, Jeff Everhart, Teresa Penedo, Jonas Backelin, Jaap Bosman Transmediacamp101, Barnical, Brandon's Educational blog, Inkblot, 2voices1song, Nellie Deutsch, Nina, Ted Curran, Dr Justin Staub, Jaraad, Henry Tapper, Jackie Regales, WikiQuals, Teochenghang, KenThinksAloud, ScottKotarides, Teahorvatic, CoolTeacherPodcast, JGousseva, Kerry Muste, iGameMom, MauriceABarry, Zac Egs, IdoLanuel, gpicone, Cristian Mihai, gluttrell, abacch03, elketeaches, SydneyFong, bottledworder, kateshrewsday, Simple Politiks, Jan Simson, Lesleycarter, poetrycurator, Jonathan Martin, oneanna65, Pak Liam, Odilets, Teachers Reflect, Keelan Foley, agencynews, starscraper99, tearmatt, clotildajamcracker, moderndaychris, Mazhar, Karen, Creative Donkey, Ashley Jillian, Ana Cristina Pratas, dloitz, MaggieMae, SimplePleasures, Manjree, Serena Turri, audedu, lejam jackson, 7th Heaven, Tuesday2, Nanxiliu, allaboutlemon, Moment Matters, Jeff Nguyen, A Ventography!, thatwritinglady, life of transition, Justin, Sebastian Raschka, Ankur Sharma, Stereotopical, MustardSeedBudget, Karris72
Retweets and mentions:
EugeneNizeyimana, Stefan Popenici, Dean Jenkins, Guven Cagdas, Sheila Stewart, Alvaro Anguix, Inland 2005, Donna Fry, Rita Silimbani, Linn Gustavsson, Allan Quartly, Liz Renshaw, Gaddaf.ly, Marcia Forbes, Jane Mitchinson, Judy Baker, HalHol, Robin Yearsley, Francesca Beltrami, Maria Joao, Vladimir Kukharenko, Elizabeth Heck, Riitta, Suominen, myweb2learn, Virginia Pavlovich, Heli Nurmi, Frances Bell, Volkmar Langer, Brian S McGowan, Roberta Ranzani, Jenny Ankenbauer, Ora Baumgarten, Whitney Kilgore, 3ksan, Claire Thompson, Rahajeng Tunjung MD, Louise Lee,
And finally some of the search terms that people used to find the blog:
- strategies of curiosity
- milk characteristics
- swan wiki
- painting girl with ball
- wings lacrosse team picture
- painting learners
- stone with blond hair
- successful hair solutions
- child connectivism with animals
- I sit for 10 hours a day sewing


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Hieromartyr Eusebius, Bishop of Samosata
The Hieromartyr Eusebius, Bishop of Samosata, stood firmly for the Orthodox Confession of Faith proclaimed at the First Ecumenical Council at Nicea in the year 325. For this he underwent persecution by the Arians, being repeatedly deprived of his see and banished. The emperor Constantius (337-361), patron of the Arians, learned that Saint Eusebius kept a conciliar decree regarding the election of the Orthodox Archbishop Meletius to the See of Antioch. He commanded him to give up the decree. The saint boldly refused to do as ordered. The enraged emperor sent a message that if he did not give up the decree, then his right hand would be cut off. Saint Eusebius stretched out both hands to the emissary saying, "Cut them off, but I will not give up the Decree of the Council, which denounces the wickedness and iniquity of the Arians." The emperor Constantius marveled at the audacity of the bishop, but did not harm him.
During the reign of Julian the Apostate (361-363), even more difficult times ensued, and an open persecution against Christians began. Saint Eusebius, having concealed his identity, went about in the garb of a soldier across the whole of Syria, Phoenicia and Palestine, urging Christians to the Orthodox Faith. He established priests and deacons in desolated churches, and he consecrated bishops who renounced the Arian heresy. After Julian the Apostate's death, he was succeeded by the pious emperor Jovian (363-364), during whose reign the persecutions stopped. Returning from exile, Saint Meletius (February 12) convened a local Council at Antioch in the year 379 on the advice of Saint Eusebius. Twenty-seven bishops participated, and it reaffirmed the Orthodox teaching of the First Ecumenical Council. The Arians signed the conciliar definition, fearing the steadfast defenders of Orthodoxy, the holy hierarchs Meletius, Eusebius and Pelagios, who had great influence with the emperor. After the death of Jovian the Arian Valentinian (364-378) came to power.
The Orthodox were again subjected to persecution. Saint Meletius was banished to Armenia, Saint Pelagius to Arabia, and Saint Eusebius was condemned to exile in Thrace. Having received the imperial decree, Saint Eusebius left Samosata by night so as to prevent tumult among the people that esteemed him. Having learned of of the bishop's departure, believers followed after him and with tears entreated him to return. The saint refused the entreaty of those who had come, saying that he had to obey the authorities. The saint urged his flock to hold firm to Orthodoxy, blessed them and set off to the place of exile. The Arian Eunomios became Bishop of Samosata, but the people did not accept the heretic. The Orthodox would not go to the church and avoided meeting with him. The heretical Arian perceived that it was impossible to attract the independent flock to him.
The emperor Gracian (375-383) came upon the throne, and all the Orthodox hierarchs banished under the Arians were brought back from exile. Saint Eusebius also returned to Samosata and continued with the task of building up the Church. Together with Saint Meletius he supplied Orthodox hierarchs and clergy to Arian places. In the year 380 he arrived in the Arian city of Dolikhina to establish the Orthodox bishop Marinus there. An Arian woman threw a roof tile at the holy bishop's head. As he lay dying, he asked her for wine and requested those around not to do her any harm. The body of Saint Eusebius was taken to Samosata and was buried by his flock. The saint's nephew, Antiochus, succeeded him and the Samosata Church continued to confess the Orthodox Faith, firmly spread through the efforts of the holy Hieromartyr Eusebius.


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White farmers won't get special treatment
FOREIGN Minister Julie Bishop has denied white South African farmers will be given special treatment after comments from Peter Dutton were labelled "racist".
Ms Bishop has clarified where the Turnbull Government stands on Australia's humanitarian visa program, while attempting to quell South Africa's offence at Mr Dutton's suggestion the country is in dire straits.
"Australia does monitor the rate of violent crime in South Africa, and there has been a dramatic increase in recent years," she told Barry Cassidy on ABC's Insiders this morning.
"Last year there were about 19,000 murders in South Africa, and that's a very high number for a country of that size."
Home Affairs Minister Mr Dutton was labelled a racist this week, when he sparked controversy by singling out South African farmers' need to flee "horrific circumstances" for a "civilised country" like Australia.
With concerns growing about the humanitarian visa program being altered to fast-track 'white' South African farmers who fear for their safety in South Africa, Ms Bishop clarified the government's position.
"I believe the humanitarian programs credibility comes from the fact that it is non-discriminatory and that each application is assessed on its merits," she said.
"That's been the case under the Turnbull Government, and as far as I'm aware, there are no plans to change that visa program."
She confirmed that Australia's High Commissioner in South Africa was holding talks with the South African Government in Pretoria, to clarify the basis of the visa program and to understand what their intentions are with land reforms that the South African Government is implementing.
"We want to ensure that those land reforms don't lead to tensions or indeed violence, and so we have made our concerns known to the South African Government in relation to land reforms more generally."
Mr Dutton's decision to examine whether the South African farmers deserve "special attention" for acceptance on refugee or humanitarian grounds led to South Africa demanding talks with the High Commissioner this week..
Foreign ministry spokesman Ndivhuwo Mabaya insisted in a statement that Mr Dutton retract the comments, saying their government was offended.
Australian Prime Minister Malcolm Turnbull stopped short of defending his minister when pressed Friday, insisting what Ms Bishop has also said, that Australia had a non-discriminatory humanitarian program.
"We have migrants to Australia from every part of the world ... and we have a refugee program that is non-discriminatory," he said.
Mr Dutton, who has drawn criticism in the past for cracking down on asylum-seekers from Asia and the Middle East, was called "an out-and-out racist" by Greens leader Richard di Natale.
He suggested the stance on South African farmers signalled a return to the "White Australia" policy, referring to laws in place for seven decades from 1901 that prevented non-white immigrants settling Down Under.
"There's no debate as far as I'm concerned, the bloke is an out-and-out racist," he told reporters.
"According to Peter Dutton, if you're a white South African farmer you are going to make a great contribution, you're not going to bludge on welfare. But if you're not white, you won't do any of those things," he continued.
Up to 500,000 white South Africans have left the country in the past 30 years, according to official statistics, with Australia ranking as the top destination.
- With AP


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I've enjoyed Kiki DeLovely's fiction in a number of lesbian and mixed erotica anthologies, so I was curious what I'd find when I snuggled up with "For the Moment" for the Sudden Sex Blog Tour.
I was not disappointed! It seems that Kiki's narrator and I have a fantasy in common: being the sole femme in a menage with two butches.
The story starts out right in the thick of the action -- with hands, mouths, and cocks already in intense, hot action. It's a little breathtaking.My ultimate butch-on-butch fantasy coming to life. I had felt them moving on top of me -- knew it was inevitable and was quite pleased it was happening so soon -- sensed its fruition just in time to catch that first glimpse of my own personal goddess-sent, ambrosia-dripping dream
Then Kiki backs up to reveal a bit of how the characters came together (no pun intended) -- the narrator, and her lover, and an ex -- and we get a chance to enjoy the sweetness of their connection. This taste of back story deepened my enjoyment of the hot and heavy action. I also particularly liked the the chemistry between the two butches, who got to get as good as they gave.
I had never before been so filled in my life, had never been able to take so much. But then again, I had never been offered quite so much either.Like all the stories in Sudden Sex, "For the Moment" is a short morsel. But it is very (ful)filling.