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Where To Get Free Tacos for National Taco Day
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"24 years old and still making the same mistakes, but that doesn't matter as long as I got a show to play and a song to write"
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Jacques R. PauwelsJACQUES R. PAUWELS has taught European history at the University of Toronto, York University, and the University of Waterloo. He is available for speaking engagements; e-mail email@example.com for details.
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Our Cape Cod inn is a lodging experience unlike any other. Each of our Brewster, MA, accommodations features an array of luxurious and convenient amenities to make sure that your stay is exemplary. We strive to think of everything so you can relax and enjoy your time here.
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Property Tax Lawyers in Westminster
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Abena Mackall
Faculty Research Associate — Ed.D., Culture, Communities, and Education, Harvard Graduate School of Education
Assistant Professor, School of Social Work
Social Contexts of Education and Human Development, Juvenile/Criminal Justice, Poverty, Qualitative Methodologies, Applied Statistical Methods
Abena Subira Mackall is an Assistant Professor at the Steve Hicks School of Social Work at The University of Texas at Austin. Mackall's interdisciplinary research draws on scholarship in human development, education, and sociology to explore the mechanisms underlying correlated forms of social disadvantage. Motivated by her experiences as a former middle school special education teacher and instructor in prisons, Mackall's research aims to provide insights into practices and policies that will enable public institutions to more effectively support individuals in contact with the juvenile and criminal justice systems. Her most recent study used in-depth interviewing to examine how adolescent arrest shapes the educational trajectories and social networks of crime-involved young men. In prior work, Mackall normatively and empirically explored the importance of in-prison education for civic and social connectedness. Mackall's research has been supported by the National Academy of Education/Spencer Foundation and the American Educational Research Association. She holds an EdD and EdM from Harvard University, an MSc in Race, Ethnicity and Post-Colonial Studies from the London School of Economics, an MSEd in Special Education from Hunter College, and an AB in Politics from Princeton University.


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General Information
Participation Policy
The Australian Professional Association for Trans Health (AusPATH) and it's affiliate organisations regularly hold courses, conferences and scientific symposia. The aim of these educational activities is to promote research and free and full discussion of scientific ideas in a respectful environment.
In line with good governance protocols, all attendees, speakers, sponsors, and volunteers at these events are required to agree with the following Code of Conduct.
We expect cooperation from all participants to help ensure a safe environment for everyone.
All events take place in a friendly environment where everyone should feel welcome, safe and comfortable to share ideas and engage in open discussion without threat of intimidation or public humiliation.
We expect all conference participants to be respectful in person and online towards other delegates, speakers, organizers, staff, and volunteers.
Photography and recording of any kind are not permitted without the explicit consent of those being photographed or recorded.
We expect all conference participants to behave in a collegial manner and to use language that is respectful, non-pathologizing and consistent with human rights standards, taking into account its shifting and complex contextual and cultural character. Ultimately, this caution applies equally to transgender health and all other formal and informal settings in which human interaction takes place. Please refer to our Language Policy.
We are committed to providing a harassment-free conference and training experience for everyone, regardless of gender, gender identity and expression, sex characteristics, sexual orientation, disability, physical appearance, body size, race, or religion. Harassment of participants, speakers, staff, or volunteers in any form will not be tolerated. Harassment includes offensive verbal comments, and other forms of using disrespectful and pathologizing language inconsistent with human rights standards, deliberate intimidation, stalking, following, harassing, photography or recording without explicit consent, sustained disruption of talks or other events, inappropriate physical contact, and unwelcome sexual attention.
These policies apply in every space at the venue related to the events and to all participants in every role.
If a participant engages in harassing behaviour, the AusPATH organisers may take any action they deem appropriate, including warning the offender or expelling them from the conference with no refund. Event participants asked to stop any harassing behaviour are expected to comply immediately. If you are being harassed, notice that someone else is being harassed, or have any other concerns, please contact a member of the AusPATH staff immediately. We will be happy to assist those experiencing harassment to feel safe for the duration of the event.
The leadership will do their best to ensure all registered participants feel safe to express themselves in a professional manner consistent with a scientific conference.
All attendees should keep in mind that meeting venues have their own internal guidelines they must follow, therefore, if any individual hotel employee is witness to any activity that is deemed by them to need intervention they have a responsibility to respond.
We expect participants to follow these rules at all event venues and related social events.
We trust that this code of conduct mirrors the views of the vast majority of our participants.
Credit: The World Professional Association for Transgender Health (WPATH)
Airport Transfers
Perth Airport is a modern facility approximately one hour away from Fremantle.
A taxi trip from the airport terminals to Fremantle will take one hour depending on the time of day. The journey will cost approximately A$50.00 – A$70.00.
All taxis are meter operated by time and distance, and operate twenty four hours a day. Taxis indicate they are vacant by illuminating their sign on the roof.
Taxis are easily accessible from the airport, there is a rank outside both the international and domestic terminals.
Within Fremantle the CAT (Central Area Transport) bus service operates for free. The Fremantle CAT bus has two routes – Blue and Red. For more information http://www.transperth.wa.gov.au/Timetables/CAT-Timetables
Banks generally open from 0930 – 1600 hours Monday – Friday. Some banks offer extended hours and some are open on Saturday mornings.Several international banks have offices in the CBD.
Decimal currency is used in Australia with the dollar as the basic unit (100 cents = $1) Notes come in $100, $50, $20, $10, and $5. Coins come in 5c, 10c, 20c, 50c, $1 and $2 denominations. Currency exchange facilities are available in most banks, hotels and airports and operate normal business hours. Credit cards are accepted at most restaurants and shops, the most widely used being Mastercard, Visa, American Express and Diners Club.
Climate and Clothing
Average maximum temperature 22°C
Average minimum temperature 13°C
For more information on average temperatures, rainfall and lots of other great information about Western Australian destinations, visit www.westernaustralia.com.au
Please ensure that along with your passport and visa, you also pack your registration confirmation letter within your carry-on luggage. You may be asked to produce this when going through customs at your arrival airport. In addition to this, please be sure to fill out your Incoming Passenger Card with all details and answer each question honestly
Eating out
The numerous cafes, gelateries, juice bars, tea rooms and coffee houses make this a perfect social city and a great meeting place.
Atrium Garden Restaurant
It's all for you… enjoy fresh seafood, crisp salads, hot international dishes, Chef's carvery and tempting desserts. The modern, spacious and family-friendly restaurant is perfect for your next celebration, especially for large groups that want to indulge in a variety of dishes that is great value for money. Adults and kids will be happy with $5 unlimited soft drinks and activity packs to keep the young ones busy while you enjoy your delicious meal.
Bar Orient
With its modern decor, live music and service-orientated staff, Bar Orient has become the premier destination for a fun night with friends or family.
Bread in Common
Opened in 2013, Bread in Common is within a 1898 heritage listed building on Pakenham Street, Fremantle. Street frontage is framed by large working garden beds.
Cicerello's has been an iconic Fremantle eatery since it's founding in 1903, offering the best of the port's amazing selection of seafood in a relaxing atmosphere. On any visit with us you can enjoy anything from traditional fish & chips the way we have been serving it for decades, premium grilled fish freshly caught and usually filleted onsite in our own fish processing room as well as a selection of local delicacies including crayfish, crabs, prawns and much more.
Little Creatures
One shared belief when Little Creatures was just a twinkle in our eyes was that breweries over the years have hardly been the most romantic of places . Hidden behind big brick walls and imposing gates, very little was left to the imagination of the passing community. It is our ambition to change all that, to become an open and transparent Brewer that welcomes all walks of life to experience the wonder of brewing. Come on down, say hi and explore our little piece of brewing happiness.
Pizza Bella Roma
Pizza Bella Roma is one of the oldest restaurant in Fremantle, first opened in 1972 by an Italian couple. The restaurant enjoys now a lot of popularity among locals as well as tourists thanks to its famous chilli mussels, pizzas and many more other dishes, all served in sizes which you won't complain about!
Sail and Anchor
The recently launched Brewers Garden café is a lush and relaxed fully enclosed garden with views to the brewery. Dine of a selection of small plate tapas offerings, steaks, salads & pub food favourites. The garden also offers tables in the adjacent alfresco dinning area on the Henderson mall, a great place to soak up the sun and watch the famous Freo buskers in action.
Electrical current is 240/250V, AC 50Hz. The Australian three-pin power outlet is different from that in many countries, so you will need an adaptor. If your appliances are 110V, check if there is a 110/240V switch. If not, you will need a voltage converter. Universal outlets for 240V or 110V shavers are usually found in leading hotels.
Exchange Rate
Australian currency fluctuates on the international monetary exchange. Therefore we recommend checking with your local bank for the exchange rate just prior to your arrival in Australia.
Goods and services tax (GST)
All prices quoted on this website are inclusive of 10% GST (Goods & Services Tax), unless otherwise specified. GST applies to most goods and services in Australia.
Registration fees do not include insurance of any kind. It is strongly recommended that at the time you register for the Conference and book your travel you take out an insurance policy of your choice. The policy should include
- loss of fees/deposit through cancellation of your participation in the conference,
- or through cancellation of the conference,
- loss of international/domestic air fares through cancellation for any reason,
- loss of tour monies through cancellation for any reason including airline or related services strikes within Australia,
- failure to utilise tours or pre booked arrangements due to airline delay, Force Majeure or any other reason,
- medical expenses (including sickness and accident cover),
- loss or damage to personal property,
- additional expenses and repatriation should travel arrangements have to be altered.
The Conference managers cannot take any responsibility for any participant failing to arrange their own insurance. This insurance is to be purchased in your country of origin.
English is also the official language for the Conference.
Secure valet parking is available at the Symposium venue at the rate of A$29.50 per day. Limited outdoor parking and metered street parking are nearby.
Passport and Visa Information
All visitors to Australia must have a valid visa to travel to and enter Australia. It's recommended to allow at least 6 – 8 weeks for visa processing. For VISA information please download the following visa information fact sheet from the Australian Immigration Office.
The Conference hosts and organisers have arranged for photography onsite throughout the Conference. The images may be used for post-Conference reports, case studies, marketing collateral and supplied to industry media if requested. If you do not wish for your photo to be taken, please inform an Arinex staff member at the registration desk onsite.
Planning your Travel
Because of time change and jet lag the Organising Committee suggests you consider arriving in Australia a couple of days prior to the Conference. This will enable you to relax and familiarise yourself with your hotel and its surrounds before the start of the Conference.
Australia operates under the Privacy Act 1988 (Cth), as amended, and the Privacy Amendment (Notifiable Data Breaches), 2017. The objective of these is to protect the right of the individual to privacy of their information.
Europe operates under the General Data Protection Regulation (GDPR) (Regulation (EU) 2016/679), a regulation in EU law on data protection and privacy for all individuals within the European Union. The GDPR aims primarily to give protection to citizens over their personal data. The legislation was adopted on 27 April 2016.
The Conference Managers comply with these legislations and are committed to protect the right of the individual to privacy of their information.
Arinex will not sell your personal information to third parties. If you believe that any information we are holding on you is incorrect or incomplete, please email us and we will promptly correct the information. You may also withdraw your consent for use of your information by advice to us in writing.
Why do we wish you to provide your information?
We require your information to facilitate provision of information to you regarding the Conference and to facilitate your participation in the Conference. Information collected in respect of your proposed participation in any aspect of the Conference will be used for the purposes listed below. You can give or withhold your consent for each or all of these uses. Please indicate your preferences when completing your registration form but please note that we will be unable to forward any information relating to the Conference or to communicate with you regarding your registration if you select 'no' to point 1.
What we will do with your information?
- Planning and conduct of the Conference including arrangements for your participation (e.g. accommodation booking);
- In the Delegate List published for the Conference;
- May also be provided to organisers of future occurrences of this Conference;
- May be used to provide you with information of other relevant events in your area of interest.
Important Notes:
- The parties who will have access to your information (subject to your preference selections on above points) are the Conference Managers, the Conference host organisation (points 1 and point 4), delegates, sponsors and exhibitors of the Conference (point 2) and any future organisers of the Conference (point 3).
The parties mentioned above will rely on your above consent indications for the purposes of compliance.
- You may withdraw your granular consent at any time by notice in writing to the Conference Managers.
- You are entitled to access the information held by written application to the Conference Managers.
For further information please see our detailed corporate Privacy Statement at link
Australia is free from many plant and animal diseases prevalent in other countries. Very strict quarantine rules apply to the import of animals and plants, which cannot be brought into the country without prior application. Animal and plant products are also restricted. For more information see the 'Information for International Travellers' on the Australian Quarantine and Inspection Service (AQIS) website, which you can access by visiting http://www.daff.gov.au/biosecurity/travel/cant-take .
Shops open from 9.00am to 5.00pm during the week with late night Perth City shopping on Friday's until 9.00pm. The largest Shopping Mall is Westfield Garden City located in Melville (only 15 minutes from Fremantle) and other suburban shopping centres are open until 9.00pm on Thursdays. On Saturday, most shops are open from 9.00am to 5.00pm and on Sunday most city shops are open from 11:00am to 5:00pm.
Perth is 8 hours ahead of Greenwich Mean Time.
Tipping is not as widespread or regulated in Australia as it is in other parts of the world. Tipping is your prerogative, a reward for service. It is customary to tip hotel porters and a gratuity of about 10 per cent is usual in restaurants if good service is received. Tips for taxis are regarded as optional.
A current valid international certificate of inoculation against yellow fever is required if passengers come from, or travel through, infected areas. Check this carefully with your airline or travel agent.


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Senior Member
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- May 23, 2003
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I am in need of upgrading my horrible belt collection but haven't found many places that have what I am looking for. For starters, I am looking for belts with bridal fronts.... at least that is what I think they are called. No edge stitching on the belt whatsoever, just a clean front. I also don't like belts with loops. Looking for a nice, elegant buckle, nothing outlandish and with minimal logo at most or no logo at all. Any help would be great as finding elegant leather belts with no edge stitching quite a chore. Examples and pics are most welcomed.


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Connecticut and New York Solar Panel Inspection, Cleaning, and Maintenance Services
Call us today at (877) 523-5223 to schedule an appointment for your Solar Cleaning and / or 12-Point Inspection, or contact us.
At SolarCare, because we care about your solar, we offer "best in class" Solar Care Services to ensure your solar investment was installed to the highest industry and code compliant standards.
When you join our SolarCare Annual Service program, you will have the piece of mind knowing your solar array is running at its highest efficiencies.
With SolarCare you can trust that your well maintained solar panels– from all manufacturers, regardless of who installed it. We provide you with the comfort, safety, and the highest return on your investment to operate your home or business
We offer a unique and specialized program for Solar Photovoltaic (PV) owners. Sign up for our Annual Solar Service Membership and have the peace of mind knowing your solar investment is operating at peak performance, and your home is safe. We know your solar array was an investment and we have developed our comprehensive Simple Clean & 12-Point inspection to be affordable.
Why you need our Simple Clean & 12-Point Inspection
Your solar was a big investment. Even though a solar electric system is relatively low maintenance, a cleaning and maintenance check up helps ensure your system is operating at peak performance to maximize your energy savings.
Our program is inexpensive, and our goal is to keep it running at its highest performance. Solar cuts your electricity bill, and we want to help ensure you continue to cut costs, while maintaining a safe system. It makes the difference between a solar system that functions optimally versus a system that just works.
Solar Panel Simple Clean
Rain and snow melt does wash away loose particulates off the panels, and there are no moving parts, but the environment deposits pollutants that rain water will not remove. We are removing the stuck-on grime, pollution and animal droppings. We developed a technique to safely clean and inspect your solar array. We use a chemical specially developed for solar modules. It is safe for your solar system, the environment, people, and pets.
The 12-Point Inspection Process
Our 12-point inspection assures that your modules and array installation is functioning in accordance with industry standards and is code compliant. After every inspection and / or cleaning a full color report is provided, within 72 hours. Our process is as follows:
- Overall Roof Inspection
- Ensure Solar Roof Penetrations aren't leaking
- Check for Corrosion and Structural Integrity of Solar Components
- Inspect panels for burn marks, discoloration, chipping which leads to defects
- Perform thermal imaging to ensure panel is operating at manufacturers stated efficiency
- Check for loose and exposed wiring which could lead to system failure
- Inspect racking and clamping to prevent panels coming loose during a high wind event
- Identify potential build up of leafs and nests under array
- Inspect electrical conduit runs, junction boxes, and ensure watertight seals and clamps are working
- Inspect inverter and utility service disconnects for leaf buildup, animal nests, and loose wiring
- Inspect labeling of all equipment which fire fighters and utility personnel require for safety
- Perform a solar production review of the overall system to ensure peak energy production
In addition to our Simple Clean and 12 Point Inspection, we offer other products and services to keep your solar optimized.
- Site and shading evaluations
- Rodent prevention screening
- Leaf prevention screening
- Winter snow removal
- Emergency repair of failed equipment
- Battery backup systems
- Electric mini-split heating and cooling systems
- EV charging systems
Call us today at 877-523-5223 to schedule an appointment for your Solar Cleaning and / or 12-Point Inspection, or contact us.
NABCEP Board Certified PV Installation Professional
SolarPlus and the SolarCare group have earned the solar industry's leading recognition of installation expertise from the North American Board of Certified Energy Practitioners (NABCEP), and is a NABCEP Certified PV Installation Professional in both Connecticut and New York. For example, there are only 29 class A PV installers in Connecticut, over 100 in New York, and we are one of them.
NABCEP is known as the "gold standard" for PV Certifications. NABCEP is the most highly respected and well established national certification organization for renewable energy professionals. Designation as a NABCEP PV Installation Professional is widely recognized to be the most important and meaningful certification of its kind in the solar industry.
PV is short for photovoltaic. PV systems produce electricity from sunlight. Most people have used a solar powered calculator or garden light, and seen solar panels on roadside signs, but PV panels can be configured to produce enough energy to power a home, school, business, or even serve as a small power plant feeding electricity into the grid. As the cost of PV systems has declined sharply over the last few years, more and more households, municipalities, and companies are "going solar". NABCEP is a mark of quality assurance that the consumer can use to know that they are choosing a qualified contractor.
Certification provides a measure of protection to YOU – the public – by giving you a credential for judging the competency of practitioners. It is not intended to prevent qualified individuals from installing PV systems or to replace state license requirements.


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Birthdays: 1928 – James Coburn, Actor (died in 2002) 1945 – Van Morrison, Musician 1949 – Richard Gere, American actor 1968 – Hideo Nomo, Former Red Sox pitcher – 2001 1972 – Chris Tucker, Actor in the Rush Hour movies 1973 – Scott Niedermayer, hockey player 1975 – Gabe Kapler, Former Red Sox player There were not a lot of important events that happened on my birthday, but there were some from the past and "present" (after I was born).
Tag Archive: haroutunian
Aug 31 2007
August 31st Birthdays/Events…My Birthday
Permanent link to this article: http://www.armenianeagle.com/2007/08/31/august-31st-birthdayseventsmy-birthday/
Aug 25 2006
Jeep Wrangler on Fire
The inspector is curious to find out if the cause of the Jeep was a malfunction of the engine or if it was caused by general wear and tear of the Jeep. – Source The Clock Online 87 wranger, bank, citizens, clock, fire, jeep, jeep fire, plymouth, plymouth state, the clock, wrangler, wrangler fire
Permanent link to this article: http://www.armenianeagle.com/2006/08/25/jeep-wrangler-on-fire/
Feb 06 2006
Armenian Eagle Origin
So who knows, I may be some rich Armenian Prince who doesn't know who he really is, but I DOUBT IT 🙂 Armenia, Armenian, Armenian Eagle, Coat of Arms, Eagle, Haroutunian, Royalty
Permanent link to this article: http://www.armenianeagle.com/2006/02/06/armenian-eagle-origin/


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No Man's Sky Highlighted at Sony's E3 display
Hello Games is a small indie company. However, this year they took to Sony's E3 stage with No Man's Sky.
No Man's Sky is an independent game that starts you off on a small planet. All by yourself.
Thats right; every player starts out on a new planet. Hello Games' founder went ahead and said they don't even know how big the universe is. For each player that picks up a copy, a new planet is created. That is pretty freaking sweet. Check out the trailer below and get psyched!


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Probably the best time and engaging diversions accessible are arcade amusements. From conventional deviations like Skee Ball to further developed pinball games, the engaging exercises made for arcade climates have dependably been fascinating. Presently, with the absolute best Wii amusements for children and grown-ups ever made, you can bring a portion of your most paramount arcade top choices directly into your home.
1. Place of the Dead: Overkill
Place of the Dead: Overkill is one of the most sizzling arcade-style Wii shooting diversions at any point made for the Wii. Utilize your Wii weapon assistant to help Agent G as he clears his path through the blood-filled roads of Louisiana to settle a standout amongst the most puzzling wrongdoings ever.
2. Mario Party 8
Mario Party 8 is the most current in the Mario Party arrangement, promising vast amounts of new gathering style arcade diversions just as new turns on old top choices. You can even embellish a cake-enriching rivalry or game-appear on the off chance that you pick!
3. Festival Games
Take the quality test, take a stab at milk jug tossing, or drop mother and father in the dunk tank (if you dare). There are more than 20 distinctive arcade recreations to browse!
4. Game Party
With Game Party you and your companions won't just appreciate exemplary amusements like Trivia or Skii Ball yet will likewise have the chance to attempt some family top choices like table hockey, band shooting, and darts in the meantime. This is the ideal game for keeping a gathering brimming with crazy children involved.
5. Pinball Hall of Fame: The Williams Collection
There isn't an arcade game so great as traditional pinball. Pinball Hall of Fame: The Williams Collection puts a dumbfounding electronic contort on an old top choice, including unlockable game highlights with mystery shocks and the capacity to play with up to 4 individuals at any given moment.
6. Place of the Dead 2&3 Return
Everybody captivated by the House of the Dead arrangement will begin to look all arcade1up artwork starry-eyed at House of the Dead 2& 3 Return. This new creation consolidates the majority of the blood, gore, and ghoulish fun from the initial two recreations and folds everything together into one spine-chilling arcade shooting game you'll never need to put down.
7. Winter Sports The Ultimate Challenge
Is it true that you are sufficiently able to contend in the winter Olympic diversions? Winter Sports The Ultimate Challenge will test your aptitudes as you slip and slide through more than nine sports-situated arcade-style distractions with an end goal to bring home the gold. Winning marvelous Wii game surveys, this is one test you won't have any desire to miss.


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You've got read our guides to every other map in Heroes of the Storm, mastered Dragon Shire , managed the Sky Temple , and looted the Tomb of the Spider Queen But there's one map that is unlike any of the others, one which calls for an entire new strategy: Towers of Doom. The Binding Destiny weapons are stage 32, deal 57-87 harm, with the axe and daggers now granting some WIS while the employees now grants some END in addition to some extra stats. The circle surrounding a greyed-out one represents what number of enemies you will have left to kill before incomes that time.
The Necrotic Sword of Doom has its own particular assault – Doom Portal , which offers 12 hits of one hundred% Darkness harm. Along with this, should you see the boss wave the left weapon in air, put together for incoming fireball attack that packs a punch. Now journey the pod down to the bottom and wait for it to move out of the way in which, revealing the door behind to unlock Doom – Halls of the Damned.
After getting returned to the foyer replay this map 4 more occasions until the achievement unlocks. It might not be a huge recreation, but it's bought quite a bit to it, and that features a plethora of Doom secrets and techniques, collectibles, easter eggs, and effectively-hidden upgrades.
Doom The Foundry Secret 2 – This secret is only for some armor but you want it for the weapon point. Nevertheless, as a result of Doom's must farm and stay alive in the early sport, it is wise to keep away from leveling Infernal Blade an excessive amount of until after both Devour and Scorched Earth are maxed out.
Now onto the final secret, proceed the mission now virtually until the very finish on the highest floor, the place it's a must to shoot the elevator connectors to drop the elevator. Update 6.sixty six has made it so the Growth Pack three taunts will unlock upon you reaching Stage 38.
Turn right at the backside of the steps to find the switch, then drop down the hole to find the door that unlocks Doom – Tower of Babel. In the event you attain the final stage of the game, you may need to face the boss, who will be defeated by leading him into and crushing him beneath close by tombstones 3 times.
Weapon – 'get x quantity of kills with x weapon' this will be the best section to trace in direction of since kill counts are very low as a place to begin majority of which are 25 kills. The Penultimate Future weapons are level 70, deal 78-108 injury, and grant some extra stats.
Right after that rigorously drop down onto the bottom and follow the trail spherical to search out secret number four, a man with the tremendous shotgun. They will range from simply killing enemies, to reaching some extent before time runs out. The Darkish Doom weapons are level 8, deal 38-70 damage, and so they now grant some Crit and the primary stat of your class.
The Harvester demon unlocks at Stage 21. Now go all the way in which back to the blue man who had the blue key, go previous him and comply with the path left to search out the key room at the finish of the corridor, this will be secret 3. Start the mission and head for the airlock that leads outdoors, once your outside climb as much as the platform ahead of you and go to the top of it, drop all the way down to the appropriate aspect and observe the pipe to a inexperienced lit door infront.
This achievement needs to be attempted on the Warpath game mode as there will likely be a Demon continually in play you could decide up both initially as the rune spawns, or when an enemy Demon is killed and they drop it. This recreation mode additionally affords a great probability to get a number of enemies together as they both defend or attempt to take the target.
You may observe your kills for this Demon by going to your Profile => Challenges => Demons => Cacodemon. For instance, as an ADC Xayah and Miss Fortune are extraordinarily good and are seen the Greatest Doom Bot Champions for Assault Harm. Take the primary left path you come across after the warp and you will discover the final secret and a Mega Health Pack.
Soar the gap after which face the way in which you came and look to your left, there's a platform that heads round the corner, follow it to search out an opening that you simply cn climb into which is your first secret. It's suggest you buy the weapon mods and try the mastery early on. You possibly can reload checkpoints to grind out kills.
Begin the mission and observe the path spherical until you must climb onto inexperienced lit platforms, climb up and again observe it spherical till you reach a much bigger plaform that you must bounce up to, soar up to the platform and behind the crates on the platform is a lever for the secret room.
On the left is a gate with secret three behind it, a cuddly toy, you'll have to clear the room of enemies first to unlock the gate then you can grab it. If the opponent has any weak point to Darkness, the injury will probably be 10. The Future weapons have a similar attack, called "Face your Future!".
In this game mode it is going to particularly track demon kills. Soar all the way down to put on you see the armor pickup and you'll see the cave into old skool Doom near the blood pools. The boss steps again a little bit and then prices in player's course adopted by a floor-pound assault that can be avoid by transferring to either route.
You will see 2 pathways main higher to the next level on both facet of the core, you will need to go to the highest of certainly one of them and look down over the sting and drop onto the pillar beneath that holds it up, on one in every of them is a secret cuddly toy, you need to be capable of see it in case you peek over the sting.


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SpaceX's Falcon Heavy rocket may be ready to launch in just a few months from now, and the company's CEO and founder Elon Musk has some exciting updates on its biggest and most powerful rocket ever built.
According to a report from Business Insider (c/o Yahoo Finance), the Falcon Heavy rocket measures 230 feet tall, and combines the power of three Falcon 9 rockets; with that in mind, the rocket makes use of a whopping 27 rocket engines, making it capable of creating over five million pounds of thrust upon liftoff. If all goes well, the SpaceX Falcon Heavy rocket is expected to see its maiden launch "in two to three months."
Putting things in further perspective, Falcon Heavy is potentially capable of carrying approximately 119,000 pounds into orbit — that's about the weight of a fully loaded Boeing 737 jet, as Business Insider noted. The rocket is also capable of carrying a small spaceship with two passengers and various items to the moon. That's not much weight compared to NASA's most powerful moon rockets — the space agency's Saturn V rocket could send about three times more mass to the moon — but for what it's worth, SpaceX's Falcon Heavy rocket is the most impressive rocket it's ever built.
With just a few more months before the projected launch of the Falcon Heavy rocket, it would appear that SpaceX is prepared to make history sometime this summer and move even closer to achieving its plans of privately funding a trip to the moon. That's long been documented as one of the company's more ambitious plans. And while Elon Musk did say SpaceX may launch the Falcon Heavy in two to three months, Business Insider noted that Musk has been notorious for setting deadlines, yet ultimately missing them and being too conservative in assessing the difficulty of his companies' endeavors.
That doesn't just apply to SpaceX, but also Musk's arguably better-known company, Tesla Motors. Automotive News opined in 2016 that the SpaceX and Tesla head honcho's tendency to run behind schedule may as well be called the "Musk Doctrine," and it's a strategy (or a tendency) that often "drives Wall Street nuts" from a business standpoint.
"It goes something like this: People do paradigm-shifting work only when they're under tremendous pressure, so the key is to ensure deadlines are always impossible. This could help explain why Musk has never launched a product on time, yet no one seems able to keep up with him."
Similarly, the Federalist referenced Elon Musk's notorious history of missing deadlines, this time talking about SpaceX. The Falcon Heavy rocket was briefly referenced, but writer Bre Payton mainly focused on the company's grandiose plans to send two ordinary tourists to the moon in 2018, and its even more ambitious hopes of colonizing Mars by 2024.
"If their track record is any indication, we can expect lofty promises that gin up headlines and draw our collective attentions away from missed deadline after missed deadline. In other words," wrote Payton, who believes that it's about time SpaceX lives up to its moon and Mars travel promises.
As for SpaceX and the Falcon Heavy rocket, Business Insider pointed out that the rocket was supposed to have its maiden launch in March. Several setbacks had forced the company to reschedule the launch to the third quarter of 2017, including a September 2016 launchpad explosion that triggered a drawn-out probe and forced SpaceX to place a moratorium on future launches until the cause of the explosion was determined. Still, if Falcon Heavy does launch as scheduled, it could prove to be a potential game-changer for spaceflight, as SpaceX's largest, most powerful, and finest rocket to date.
[Featured Image by Roberto Gonzalez/Getty Images]


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Test Drive of the Cross Roads Ritual
So, I finally found time to carve out a ritual space in my (relatively) new apartment to test the draft of the
Breaking down mystical practice and crafting new ritual tech from primary source texts.
So, I finally found time to carve out a ritual space in my (relatively) new apartment to test the draft of the
In Part I, I talked about the principles which make creating an artificial spirit work. In Part II, I hashed
http://onefootwalking.wordpress.com/category/science/homunculus-science/ I've talked a little bit about Servitors or Artificial Elemental Spirits on my blog. I'd like to take this
*** Nudity Alert*** If you find cartoon body parts offensive, I suggest you do not look any further. Classical art
One of the reasons we need other people to talk to about our practice is so that, when we have
I'm sure we can all think of someone, perhaps on a mailing list, perhaps in a coven, maybe even in
"America's strength is not our diversity; our strength is our ability to unite people of different backgrounds around common principles."


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Post Wedding Archives - Photography Storytelling - Archive
Destination wedding British Columbia Canada This Destination wedding in British Columbia, Canada was a great experience. We loved covering the wedding of Aditya & Stephanie, a lovely couple living in the area of British Columbia. BC is a very scenic place to hold one's wedding, as it combines interesting indoor and outdoor locations to act Read more ..
Wedding art photographer Crete Greece. With Niko & Nadia we had a great time while shooting their post wedding art shoot or as they call it next day shoot. The outcome was great and the couple was awed by the end result. We did put quite some research as to where will the photography session Read more ..
Wedding photographer Crete With Teti & Mihalis we had great fun in producing their wedding art images, especially the ones on the blackboard. It was a process that took some time to paint and set up, along with its post-processing, but the result was rather interesting and visually appealing. Teti & Mixalis are the kind Read more ..
Destination wedding in Gurgaon, India


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By Ali Ünal
In his book Telling Stories: Postmodernism and the Invalidation of Traditional Narrative, Michael Roemer sets out to find the roots of traditional storytelling. His main argument is that traditional story has relied on characters taking action even though such acts, from time to time, may prove to be ineffective. It is, however, important that protagonists and heroes are driven by their consciousness to act in order to attempt to change the unchangeable. According to him, the urge to act is almost inevitable.
"Pascal says all our troubles spring from the fact that we cannot sit in a room and do nothing," Roemer writes. "Locke speaks of our 'restlessness' and Hegel of our Unruhe—our disquiet. We are not free to do nothing—to be accepting and at peace—because consciousness, which is neither willed nor freely chosen, but mandated by our very existence, obliges us to act."
To act. To do something.
This is one of the first things I say to my creative writing students in a workshop. Creating a character is the most essential part of storytelling and establishing a conscious desire for the said character is the first step. Conscious desire, or as Robert McKee puts it, "visible desire" will give an individual the authority, agency, and power they need in order to act out their lives. It will also give them a direction. Without a character, there's no story. Without a direction, there is no character.
James Wood talks about three layers of motivation Dostoevsky's characters have: Announced, Unconscious, and Revelatory. Announced motivation, or visible/conscious desire, is what drives the story's plot and what makes the characters go out of their comfort zones to fight the proverbial dragons. Such a desire announced to the reader or articulated by the character will also carry a deep meaning within, a meaning our character will and should find out at the end of their journey. This is what makes the storytelling a creative art: Exploring the human condition through desires, ambition, and passion.
A character sitting on their couch philosophizing about the world doesn't offer a compelling story. It provides a valuable essay of the self, it renders the individual with intellectual acumen, but an internal quest without an external one will arguably pale in comparison. To me, the most compelling way of flushing out that "essay of self" in order to reach that deeper meaning is to give the character a purpose, a motivation, a want of wants.
"Even the characters paralyzed by the meaninglessness of modern life," Vonnegut famously asserted, "still have to drink water from time to time."
We tend to contextualize stories and characters as the natural products of conflict and tension, i.e, plot. In the end, the character's emotional maturity or physical prowess allows them to overcome those barriers and thus grow and change at the resolution of the plot. However, I prefer to see a character as a function of their desire rather than a product of the plot's conflict. It's the desire that drives them and the story. If a character truly wants something, then there is no way that they won't come across conflicts on their way to achieve it. Just like our actions being inevitable, the tension and conflicts will have to arise out of the character's desire. Even if there is no conflict, the character will have to conjure up one—be it internal or external. Because then, the character will overcome the barriers of their own, and not of their creator.
Establishing a character's visible desire will constitute the façade or exterior of this building you'll call the protagonist. Earlier drafts will work on the construction of that building. As you revise and move through the revisions, you'll now be able to figure out the unconscious, or invisible desire of that protagonist. In other words, you'll start exploring the inside of that building. What does the interior look like? How does the interior shape the exterior? How intricately is the interior built? This will be, as the name suggests, invisible to the writer at first, and even to the character. That's where the compelling story will come out.
Of course, finding out the invisible desire/motivation will take a lot of time and a lot of revisions. As you get to know more about your characters, you'll spend more time inside of their minds. It's perhaps important and advisable not to establish an unconscious desire from the get-go. Giving your character room to improvise and construct their own inner worlds might turn out to be more effective. Sometimes, power resides in not wanting to be the master of our creations. Nabokov says that he's the master of his characters. If a character crosses the street, it's because Nabokov wants him to cross. Pushkin is known to have said of one of his characters, "Do you know my Tatiana rejected Onegin? I never expected it of her."
Which type of writer you would like to be is of course up to you, but I tell my students and myself to always have an open mind and give their characters some room and opportunity to grow on their own. Let them find their own voice.
To write a story or to create a character is not to solve a crossword puzzle. Rather, it is to create one with blank and blacked-out squares, both of which reveal the character's external and internal quest in harmony. This is how I approach storytelling, and this is how I teach: The chronicle of the character's desire. Because writing, in and of itself, is an investigation and everything a character does is a crime to solve, as it were.


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Police-community relations at forefront of NAACP convention
Cincinnati Mayor John Cranley advises driving around parts of Cincinnati to see a city reborn.
Cranley told NAACP delegates the rebirth came after the city grappled with police-community relations, but forged an agreement that brought many voices to the table.
"In fact, even though we've made progress, I'm inviting the Justice Department back in to update our agreement because we want to get ahead of any issues that may resurface," Cranley said.
But one community leader, Iris Roley, who worked on the Police Collaborative Agreement said, "He wants to rush and say we need to redo the collaborative. He's the only one not at the table. We've been meeting for 15 years."
There is a call among these delegates for accountability, better training and legislation that will permanently shift this issue from discussion to reality.
Fran Jackson, president of the Oxford Branch of NAACP, said, "Young people are hurting. Black men are being killed time and time again and there is no justice."
The NAACP wants the presidential candidate to pledge to do the following within the first 100 days of taking office:
- Cut off funds to law enforcement agencies found to have a pattern of discrimination.
- Allow the DOJ subpoena power to obtain internal documents from agencies under investigation.
- Create regulations for data involving deaths.
- Create a federal code of conduct for use of force.
- Establish a federal independent review board to investigate shootings of unarmed civilians.


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Grand Opening Business Event; Men's Vegan & Organic Grooming Clinic
Manscape & Massage Clinic, a revolutionary new business concept. A full service grooming clinic offering Manscape - Massage - Beard & Barber - Spa.OKLAHOMA CITY, OK, UNITED STATES, September 11, 2017 /EINPresswire.com/ -- Manscape & Massage Clinic, a revolutionary new business concept. A full service grooming clinic offering Manscape - Massage - Beard & Barber - Spa. Proudly using Organic & Vegan grooming products.
Oklahoma City, Oklahoma: A new approach to the grooming industry is headed to downtown Oklahoma City. It encompasses their own all organic and vegan grooming product line, Manscape Supply Co. The clinic approaches grooming as a head to toe experience, offering Beard & Barber services, Manicures & Pedicures, Facials, and their signature Massage services.
Manscape & Massage Clinic will celebrate its Grand Opening October 1, 2017 - 4-7pm, OPEN to the public at their clinic located in Automobile Alley. The event will include the unveiling and sampling of their complete organic and vegan grooming product line. They will also be featuring Oklahoma farm to table heavy hors d'oeuvres by private chef Justin L'herisse. Wine will be served by neighbor Waters Edge Winery. DJ Vince Lepeltier will be keeping the atmosphere at a light party mode all event long.
Manscape & Massage Clinic strives to be eco-friendly utilizing the best sweet -musky - earthy masculine scents and elements on earth… believing masculinity can encompass compassion for the planet.
Ben Grunewald
Manscape & Massage Clinic
(405) 388-5100
email us here


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We're launching a new communication tool at the electSloan campaign to help keep supporters in Hastings-Lennox & Addington informed about what our candidate Derek Sloan and his campaign team are doing around the riding. This is the first edition of our Weekly Update - we hope you find it informative.
We've had a great few weeks, including some excellent training in Ottawa and some boots on the ground in H-L&A—and we've definitely needed our boots!
Derek and Campaign Manager Eric Lorenzen attended the Conservative Party's "Victory School" Jan. 24-26 in Ottawa. They were trained on a range of topics, including get-out-the-vote strategies, campaign organization, and voter outreach tools. Derek also participated in a "Super Caucus" meeting in the West Block of the Parliament Buildings with the CPC caucus and candidates from ridings across Canada. He had lots of opportunities to meet and learn from sitting MPs and Party strategists!
Once back from Ottawa, canvassing resumed, with Derek knocking on doors in Madoc and our National Super Canvass event in Napanee last Saturday & Sunday. We had a great turnout of volunteers, including some Queen's University students and candidate Tim Durkin & some of his team from Bay of Quinte. Canvassers wound up at Napanee's Waterfront Pub on Sunday to watch the Super Bowl with Derek. We hope to return the favour to Bay of Quinte on Saturday, Feb. 9--let us know if you'd like to join us! It's a lot of fun to get out & get to know fellow Conservatives. If you haven't canvassed before, you'll be given some simple instructions, and you are never sent to a door alone.
This coming Thursday, Feb. 7, Derek will be at a meet-and-greet at Deadleaf Barber Shop in Napanee, 42 Dundas St. E., from 3:00-6:00. Come on out for a drink, some great conversation, and even a haircut if you need one. And bring a friend!
Teams will also be out knocking on doors this week in Flinton and in Tweed. We are building our list of volunteers, so if you'd like to get involved, please email us at email@example.com.
And here's something else you can do to help electSloan—all without setting foot out in the cold, the snow and the slush. Are you on Facebook? If so, please "like" our page (www.facebook.com/ElectSloanHLA) and then, please click on "Invite Friends" on the right side of the page. This is a great (and free!) way for us to build awareness of the campaign and share our positive, Conservative message.
Finally, did you know that when you donate to our local Conservative association, that money stays right here in HLA to help elect Derek? And up to 75% of your donation could be eligible for a tax credit on your 2019 tax return. Election campaigns are expensive, and the money needed comes almost exclusively from donations from individuals in our riding. We can accept donations from individuals only (not from corporations or businesses). Cheques should be made payable to H-L&A Conservative Association and sent to PO Box 111, Madoc, Ontario, K0K 2K0. We cannot accept cash or credit card information through the mail; however, you can donate online at: www.hlaconservative.ca/donate.
NOTE: The new annual contribution limit for 2019 is $1600, up from $1575.
Thanks for your interest in Team electSloan - together we can send Derek to Parliament and elect a Conservative government in October.
Team electSloan


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Off Color Brewing Baits Beer Lovers With New Taproom, and Other Dining News
Plus: Theater on the Lake debuts its crown jewel, a new hand roll bar at Mana Food Bar, and more
The 15-seat Anaba Handroll Bar (1742 W. Division St., Wicker Park) has set up shop in the front section of Mana Food Bar's dining room. It's a collaboration between Mana owners Jill Barron, Susan Thompson, and Soon Park, who owns Chef Soon in Woodbridge. Hand rolls—roughly a dozen of 'em—come packed with either veggies or sustainable seafood such as salmon, crab, and hamachi.
Off Color Brewing is baiting beer-lovers to Lincoln Park with Mouse Trap (1460 N. Kingsbury St.), the company's new taproom. In addition to 16 draft lines, there's also a roster of bottled beer, cocktails, wines, and coffee.
With the recent openings of the Green Room Tap (1801 S. Allport St., Pilsen) and the Avondale Tap (3634 W. Belmont Ave., Avondale), the Aberdeen Tap and G&O family adds two new southside bars to its West Town–based brood.
On the heels of a $5.9 million reno, Theater on the Lake has debuted its crown jewel, a Midwestern restaurant called, aptly, the Lakefront (2401 N. Lake Shore Dr., Lincoln Park). Cleetus Friedman (City Provisions, Fountainhead) helms the kitchen at the 125-seat affair.
Moto: The Cookbook is now on sale. The tome documenting Homaro Cantu's renowned West Loop restaurant was underway prior to the chef's death in 2015. But now it's a way to remember Cantu's culinary legacy—you can buy a copy on Amazon here.
The Perfect Order at Kasama
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Individually Yours
Typical Valtra features such as uniform weight distribution, high PTO power, spacious cabin and favorable power to weight ratio make Valtra ideal. The Auto-Guide steering system and the ISOBUS connection for tools provide the finishing touches to the product . Our customers appreciate the reliability and low costs over the entire product life cycle.
"Others go as far as they can, we go as far as we want"
Link to manufacturer www.valtra.de
Hof loaders from Giant convince by their performance, the compact size, safety and comfort.
With 36 different models from 20 - 76 hp, small to large, 69 attachments as well as 8 different equipment, Giant offers a wide selection.
"Compact. Agile. Strong."
Link to manufacturer www.tobroco.nl/de
Low power demand on the market, thanks to parallel driven mowing discs.
Extremely clean cut due to the highest cut overlap.
High strength and easy maintenance thanks to individually lubricated mowing discs.
"Mow grass as your animals need"
Hay bale press
With more than one hundred years of experience in baling presses, Lely Welger sets standards in quality and reliability. From the pick-up through the pick-up system to the bale chamber; These bale presses have been developed for high effective throughput.
"This makes round balers a joy"
Turning with the Lotus tedder is the basis for a timely harvest and optimum feed quality. Lotus tedders are perfect thanks to their unique hooks and their enormous stability. Due to the prong position and shape, the crop is picked up optimally and an unsurpassed performance is achieved. In combination with the robust design, higher travel speeds are possible.
"A fast wilting promotes feed quality"
Link to manufacturer www.lely.com/de
Tractor mower
The tractor with front steering is powerful, and especially reliable and secure on slopes. The chassis is characterized by a very low center of gravity that ensures stability on slopes, without compromising ground clearance. The tractors Pasquali have the Self Cleaning System ®, an innovative dual fan system for a constant cleaning of the radiator and the air intake grille. It protects the cooling system against whirled dust and dirt that can have a strong negative influence.
"The advantages of a long tradition"
Link to manufacturer www.pasqualiagri.it
Agricultural trailers
Lochmann adapts to the conditions in the mountains for its customers . They have learned to rely on specific priorities: Robustness, ease of use, off-road capability and a high level of security. As a result trailers from Lochmann comply in every detail with the European safety standards. Bring home your successful harvest, materials or equipment safely and comfortably with a trailer from Lochmann.
"Reliable partner always with the correct solution"
Link to manufacturer www.lochmann-erich.it


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Trump DOJ threatens King Co. over immigration enforcement
King County's stance as a "sanctuary jurisdiction" drew another letter from the U.S. Department of Justice Wednesday, this time threatening to subpoena county officials for documents.
The letter, addressed to King County Council chair Joe McDermott, asked for any documents that might have instructed law enforcement personnel in how they communicate with the DOJ and federal immigration agencies.
Should the DOJ find that King County isn't abiding with its requirements properly, the county would have to pay back federal grant money issued under the Byrne Justice Assistance Grant program, Bureau of Justice Assistance Director Jon Adler wrote in the letter.
McDermott, who said he read about the letter on Politico before it even hit his inbox, dismissed it as a hollow threat and a press stunt.
"This is nothing more than bullying and intimidation by (President) Trump and (Attorney General Jeff) Sessions," McDermott told SeattlePI. "We fully comply with federal law, we do nothing to inhibit communication between our officials and federal agencies. As we've told them before, we are fully compliant."
It's the second letter King County officials have received from the DOJ threatening action over the county's promise to only intervene in immigration issues when required by law. The first letter was sent in November.
Seattle and King County officials, as well as Washington Gov. Jay Inslee, have pledged that the region should be welcoming for all people, regardless of immigration status. Seattle and King County law enforcement have been directed to not ask for immigration status unless required to do so under a federal warrant, and other local agencies are directed to do the same. It's a sort of "don't ask, don't tell" policy meant to make sure people feel safe contacting law enforcement and seeking medical help regardless of their immigration status.
RELATED: Seattle mayor, city attorney sue Trump over sanctuary city threats
Inslee's order last February directed that state agencies shouldn't collect personal information beyond what was needed to offer services and that the state shouldn't be a "willing participant in promoting or carrying out mean-spirited policies" sent down from President Donald Trump's administration.
Seattle Mayor Jenny Durkan, a former U.S. Attorney, issued a statement about Wednesday's letter that echoed McDermott's sentiment about it being a threat and promising a fight.
"As a former U.S. Attorney, I'm prepared for a legal fight with this administration," Durkan said in the emailed statement. "Let's be clear: It's a fight that Donald Trump will lose."
Durkan and McDermott also both said the threats do little more than instill greater fear into immigrant communities -- certainly not making the community safer.
Shortly after Trump's election, the DOJ threatened to pull federal grant funding from any cities that operated as sanctuary jurisdictions. Seattle City Attorney Pete Holmes sued over the threat, arguing that it wasn't legal for the feds to pull funding when municipalities hadn't violated federal law.
Seattle was set to receive about $2.7 million in DOJ grant funding in 2017. Wednesday's letter suggests that the county could have to pay back 2016 funding as well.
Daniel DeMay covers Seattle culture, city hall, and transportation for seattlepi.com. He can be reached at 206-448-8362 or firstname.lastname@example.com. Follow him on Twitter: @Daniel_DeMay.


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Is it possible to change the scope of the existing object (such as JDBCProvider) on Websphere (more specifically, version 8.5)?
I can't find that option in the Admin Console neither find information how to do it with scripting, but it should be possible? It's less invasive operation than deleting the object and re-creating it in other scope.


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Author: Harun YahyaPublisher: Goodword booksYear: 2004Language: EnglishPages: 94ISBN/UPC (if available): 8178983664
By the Good Word, most perceive it to mean being complimentative, expressing love or speaking in an inspiring manner. However, the type of good word Allah refers to in the Qur'an means something quite other, and is more comprehensive, although it also includes the above-mentioned meanings. Allah descries what the good word is with the verse; Who could say anything better than one who summons to Allah, and acts rightly and says, I am of those who submit to Allah? (Surah Fussilat, 33)In other words, the Good Word is that which summons people to Allah and the Qur'an. And those who utter this good word, that is, those who call to Allah, are the believers.This book, rather than merely describing what the Good Word is, also focuses on the loss upon those who avoid it, in the light of the verses of the Qur'an. Unlike those who resist the call, however, those who adhere to it will be rewarded generously. This truth may be recognized in this world, but will become apparent in the Hereafter. Witnessing he ultimate futility of one's efforts once in Allah's presence will surely be a profound disappointment, incomparable to any other form of grief. The only way to avoid this disappointment is to adhere to the Qur'an, and every Good Word offered to remind us of its verses, before it is too late.
IntroductionThe Good Word is Calling To AllahComplying with the Good WordSpeaking the Good WordThe Fate of Those Who do not Follow the Good WordWhat the Believers Gain by following the Good WordThe Last WordThe Deception of Evolution


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The Angular Shader, also known as an Angled brush, is a flat brush cut on an angle. You can use it to do thin or thick lines. Useful for precise strokes, tight shading and highlighting. The angular brush is especially favoured by artists who love to paint roses. Check out this demo on YouTube of painting one-stroke roses and leaves with Angular Shader brushes. (You could get the same effect using our Rose or Berry one-stroke cakes!)
- Handle: long, painted wood
- Brush shape: Angled-flat
- Brush Size: #6 which is 1/2 inch wide


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When Aricept (donepezil) was first approved by the FDA in 1996 for the treatment of Alzheimer's Dementia (AD), there was an almost euphoric sense that we were finally beginning to make progress in treating a previously untreatable disease.
While the data were not overwhelming, it was clear that patients on Aricept experienced a slower cognitive decline than those on placebo. Two other companies quickly rolled out their own cholinesterase inhibitors (CIs), both sporting data comparable to the original, though there were some significant differences in side effect profiles and ease of use, with Exelon conspicuously disadvantaged by a 31% incidence of vomiting as a side effect (see TCR Vol. 1, No. 6, 2003, for a review of Aricept, Reminyl – recently renamed "Razadyne" – and Exelon).
It was nice to finally have something effective to offer patients with AD.
Well, the situation is very different today. A recent influential article has thrown into question the whole notion that CIs are helpful in AD, and Great Britain is seriously considering a proposal to drop all CIs from the formulary of the National Health Service.
What's going on here?
Let's take a close look at the Lancet article that stirred things up (Lancet 2004; 363:2105-2115). Called "AD2000," the study was conducted in Great Britain, funded entirely by the National Health Service, and was unique in that it measured the effectiveness of a CI over a three year period, rather than the standard six month length of most industry trials.
A total of 486 patients with AD were randomized to one of three arms: Aricept 5 mg QD, Aricept 10 mg QD, or placebo. In order to ensure that recruited subjects were representative of the populations most doctors are likely to see, patients were admitted if their clinicians believed they had AD according to DSM-IV criteria. There were no exclusion criteria – patients were admitted even if they had significant medical, neurological, or psychiatric comorbidity. In contrast, in most CI drug trials, inclusion requires symptom ratings with multiple research scales, neuroimaging, and the lack of significant comorbidity. Such study criteria have been shown to exclude over 90% of community-diagnosed AD patients from studies, leading many to question the generalizability of such data to the patients we see in our offices (J Am Geriatr Soc 1997; 45: 923- 928).
This article originally appeared in The Carlat Psychiatry Report -- an unbiased monthly covering all things psychiatry.
Want more, plus easy CME credit?
Subscribe today!
At any rate, the primary outcomes variables in this study were: 1. Time to institutionalization; and 2. Time to disability (defined as the loss of the ability to perform certain basic activities of daily living). While this choice of outcome measures may seem reasonable, almost all industry-funded studies use very different outcome measures, the most common of which is a measure of cognitive function, the ADAS-Cog (cognitive portion of the Alzheimer's Disease Assessment Scale).
The ADAS-Cog has consistently shown a 2.5-3.5 point benefit of CI's over placebo, a difference that is statistically significant. But is this clinically significant? Since the highest possible score on the ADAS-Cog is 70, a 3 point separation between drug and placebo represents about a 4% improvement in the scale. Because of concerns that such a small improvement in cognition might not be clinically relevant, most of these studies include a global clinical rating of improvement as a primary outcome, generally the "Clinician Interview- Based Impression of Change scale with caregiver input" (CIBIC-Plus). This is a 7 point scale, ranging from 1 (markedly improved from baseline) to 7 (markedly worse). The drug-placebo difference is typically 0.3-0.5, or, in terms of percent, about 6% benefit over placebo. Again, while this is a large enough separation to achieve statistical significance, its clinical significance is debatable. (For an excellent review of these studies, see N Engl J Med 2004; 351:56-67.)
Nonetheless, many of us have heard that CI's have been shown to delay nursing home placement by a good six months, and, if true, this certainly appears clinically relevant. Unfortunately, it turns out that there is no solid empirical basis for this truism. The "six-month delay" is an estimate based on the fact that in untreated AD, the ADAS-Cog worsens by 7 points per year, and so the typical 3.5 point benefit due to CI's slows the course of AD by six months, presumably delaying nursing home placement by that amount as well. This logic isn't bad, but the Lancet study was the first to empirically test whether this assumption is accurate.
Enough methodology! Here are the Lancet results:
1. At the three year endpoint, there was no difference between Aricept and placebo in rate of institutionalization or progression to severe disability.
2. On the MMSE (Mini Mental State Exam), patients on Aricept consistently averaged about 1 point higher than patients on placebo, throughout the study.
3. There were no significant differences between Aricept and placebo in behavioral and psychological symptoms, time spent by caregivers, or formal care costs.
This is the short version of the results. The study was complex and some of the interim results reflected better on Aricept. But the bottom line is that the first long-term controlled study of a CI for AD showed it to be only marginally effective for cognition (assuming that a 1 point separation on the MMSE is marginal), and relatively ineffective for delaying institutionalization or disability.
So, what does this data mean for our practices? Should we stop prescribing CI's for patients, on the theory that the cognitive benefits are extremely slim, and the long-term functional benefits are nil? Well, according to the major government medical institute in Great Britain, that is exactly what we should do. The National Institute for Health and Clinical Excellence (NICE) recently issued draft guidelines on the use of CI's in dementia (free download at http://www.nice.org.uk/page.aspx? o=104058). Their recommendation was that Great Britain should remove all CI's and memantine from the NHS formulary because of a lack of demonstrated cost effectiveness.
That's a pretty radical move, and one that is being bitterly disputed by medical societies throughout Britain. Much of this battle is being fought in a rarefied landscape of pharmacoeconomic statistics, and we will not drag you through that terrain!
At this point, the bottom line is that while CIs do yield a small cognitive benefit in patients with AD, they are expensive and they are unlikely to delay either nursing home placement or the development of severe disability. On the other hand, given the recent study completely discrediting Vitamin E as a memory-enhancer (N Eng J Med, 2005, 352:2379-2388) we have no other medication to offer our demented patients. For this reason alone, CIs are likely here to stay, at least until something better comes along. Of course, you could resist the temptation to whip out the prescription pad and focus your efforts on behavioral recommendations for the patient and family that are less costly and sometimes as effective, such as encouraging daily structure and providing environmental cues. (There are some good specific suggestions in a caregiver handout at http://alzheimer.ucdavis.edu/ careg/media/pdf/dementia handout.pdf.)
TCR VERDICT: CIs: Minimal benefit, but what else do we have?


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Take address data from one site and submit to another website as the program is running to get the lat and long.
Enclosed is the rip file and screen shots exampling it
There is something wrong in your "address" capture. I made another "TestAddress" capture and use it in the input transformation of formfield. Please take note that when you use args.InternalDataRow, it will produce an error during building but works well once you run it.
Best regards,


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Garage Door Spring Center Bearing Bracket, 6"
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