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Resigning as General Manager of the Universe: Five Keys to Finding Balance, Reducing Stress and Avoiding Burnout In the Midst of the Chaos
Monday 2:45 – 3:45 PM
Session Description
The life of an HR professional is a colossal collision between thousands of things pulling at your time–leading to overwhelm, stress and burnout. In this interactive and fun session, you will learn the five key strategies to "resign as general manager of the universe" and leave with practical tips and tactics to reduce stress, set boundaries, say no, be more productive and take back your own life.
Kim Becking
Kim Becking is an engaging, high-energy, fun and impactful motivational keynote speaker, change and leadership expert and best-selling author who helps others conquer change, boost resilience and build a Momentum Mindset® to accelerate success no matter what.
Kim has not just survived, but thrived change and challenges in business and life. As an attorney, serial entrepreneur, communications strategist and "recovering" political consultant, Kim has conquered the ever-changing tough worlds of business, government, and politics. She's also conquered breast cancer.
Her expertise on resilience and thriving in the midst of change has been featured in national media such as People, SELF, The New York Times, USA Today, Good Morning America and Lifetime Television.
She provides practical tools and strategies to effectively manage change and deal with difficult people, tough conversations, and hard issues. After hearing Kim, audiences leave ready to take her relatable lessons and practical solutions and put them into immediate action.


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Britain's biggest annual bike show starts this week. Cycle 2008 takes place at Earls Court, London, over October 9-12.
This year, the orgnisers are promising more floorspace and more exhibitors than ever before, with a number of top manufacturers signed up to show you their 2009 bikes and products.
Names include Campagnolo, Cannondale, Condor, Mavic, Rapha, Scott, Shimano, Specialized, Trek, and more. For many people it'll be their first chance to see the new Campagnolo 11-speed components in the metal, and check out Shimano's new 2009 Dura-Ace groupset.
A whole host of stars from the world of cycling will also be at the show, including Olympic and World Champ Nicole Cooke, David Millar, Paul Manning, Shanaze Reade and many others.
Cycling Weekly and sister magazines Cycle Sport and MBR will be there on stand B10.
You can find a full list of exhibitors on the show's website.
In addition to the new bikes on show there is also a host of features and activities, including two test tracks where you can try out a range of next year's bikes.
Making a return will be the popular trials and BMX displays, a series of seminars and talks and a fashion show.
Advance tickets cost £11 for adults and £5.50 for children (under-fives go free) – concessions are also available. You can book them online or by calling the telephone hotline on 0844 848 0133.
We'll be covering Cycle 2008 in full here on www.cyclingweekly.com with exclusive photo galleries and info on all of the hot products at the show from Thursday October 9
Cycle: www.cycleshow.co.uk.

subset: commoncrawl


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Meet our Staff
Dr. Wilhemina Fry, PharmD.
Owner and Operator of Stephens Compounding Pharmacy. She has a Bachelor of Science Degree in Chemistry, a Doctor of Pharmacy Degree and has completed a Post Doctorate Residency in Pharmacy Practice. She has Specialty Certifications in both Hormone Replacement Therapy and Veterinary Compounding. She is currently completing a Fellowship in Anti-Aging, Metabolic and Functional Medicine.
Dr. Mary Beth King, PharmD.
Mary Beth received her Doctor of Pharmacy Degree from the South Carolina College of Pharmacy in 2017. A part-time resident of Hilton Head for over 10 years, she moved here full-time and joined our team in 2018 as a Compounding Pharmacist. She is also a specialist in Diabetes Care.
Kelci Daly
Kelci joined our team in 2019 as an Administrative Assistant and Compounding Technician. She has years of experience in both medication compounding and direct patient care related focuses..


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Dolly, Diana, Cher & ABBA: 70s musical divas on the big screenNovember 9, 2017 By Go Back
Many top musical divas of the 1970s found their way to the big screen, but in a fallow period for straight-up musicals they found interesting and diverse projects to utilize their talents. This month we have five glorious divas from different musical backgrounds taking over tinseltown.
Dolly Parton – 9 to 5 (1980) and Rhinestone (1984)
Dolly Parton was almost immediately ready for the screen, having made her debut as a singer on TV's The Porter Wagoner Show. Dolly was at the peak of her power in the 1970s with hit records, multiple variety shows and a career that transitioned from country music to pop. The increased notoriety, freedom and fame brought offers like her first film 9 to 5. Dolly was initially hesitant, famously so green she memorized the whole script rather than just her scenes, but eventually signed onto the film under a contractual clause that let her write and perform the title track.
When it comes to Dolly Parton's acting, what she understands best is what Dolly Parton fans want: campy humor, great outfits, and a lot of heart along with some Smoky Mountain truth-to-power. She is ever the brassy blonde who stands up to bullies and always has a great one-liner up her sleeve. Even goofy movies like Bob Clark's 1984 Rhinestone, a country music take on Pygmalion with Sylvester Stallone as Dolly's Eliza Doolittle, shines with effervescence when she's on screen. Dolly doesn't act often, but when she does the role always fits her like a glove, playing directly into her strengths as a performer.
Diana Ross – Lady Sings The Blues (1972)
By the 70s Diana Ross had almost a decade of fame under her belt with The Supremes and her own massive solo career. Diana Ross had flirted with acting on tv, but it was the chance to play jazz icon Billie Holiday that got her more into the idea. She famously petitioned Motown executive and Lady Sings the Blues producer Berry Gordy hard for the role and won it against bigger acting names Diahann Carroll, Cicely Tyson, and Lola Falana. The casting was controversial, but once the film came out audiences were won over and Ross went on to be nominated for an Academy Award for her big screen debut.
Diana Ross's short film career happened quickly, with 1975's Mahogany reteaming her with Lady co-star Billy Dee Williams, and also featured costumes designed by Ross. She once again petitioned hard for the lead in The Wiz, which was controversially re-written for an older actress. Though the film isn't always fondly remembered, her songs were nonetheless iconic, including her chart topping duet of "Ease on Down the Road" with Michael Jackson. Though she has limited herself to a couple of small screen roles since, Ross's biggest legacy in the Hollywood landscape has been through her award-winning daughter, actress Tracee Ellis Ross.
Cher – Come Back to the Five and Dime, Jimmy Dean, Jimmy Dean (1982)
Unlike the other divas on this list, Cher always had aspirations to be an actress. Early in her career though she'd only managed a few roles with Sonny Bono in 1967's critically reviled Good Times, and light exploitation melodrama Chastity. Though she of course had plenty of 70s success with The Sonny & Cher Comedy Hour, it wasn't until her divorce and a slow point in her career in the 80s that she returned to serious acting. Cher had moved to New York with the intention to study under famous acting guru Lee Strasberg when Robert Altman encouraged her to audition for his Broadway remount of Come Back to the Five and Dime, Jimmy Dean, Jimmy Dean, the role that would change her career.
That play not only got her a part in the brilliant, subtle film adaptation of Jimmy Dean alongside award winning actresses like Sandy Dennis, Karen Black and Kathy Bates, but it also brought her skills to the attention of Mike Nichols who'd go on to cast her for her dramatic skills in Silkwood . That role would establish her as a serious actress and would lead to her first Oscar nomination. Though she's only appeared in a little over a dozen films, Cher has a unique talent to strip away her pop diva persona and disappear into a role whether it's as a tough-as-nails biker in Mask or a put-upon housewife in her Oscar-winning role in Moonstruck.
Anni-Frid Lyngstad & Agnetha Fältskog – ABBA: The Movie (1977)
Of course all divas weren't quite as camera ready as Cher, Diana and Dolly. When it came to translating the fabulous work of Anni-Frid and Agnetha of the band ABBA to the big screen, their disinterest in acting and English skills definitely hurt the Swedish supergroup's chances. Unbeknownst to most of the world though, ABBA had an ace up their sleeve in the talented director of their famous music videos: future Oscar nominee Lasse Hallström.
ABBA: The Movie is a brilliantly constructed mix of documentary footage and a light comedic story of an Australian journalist constantly shut out of ABBA interviews during Australia's ABBAmania. You can already see the beautiful visual style with swooping crane shots and trick editing that Hallström would develop for films like My life as a dog and Cider house rules. On top of that, Hallström allows the band to be themselves and translates their work through performance while using his fictional journalist to inject the film with self-effacing Swedish humour that questions the nature of fame and stardom for these "nice, clean and quiet" people. Sort of an anti-Hard Day's Night, the film allows pop divas to do what they do best: perform fabulously.


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4 Definitions of Tenant
The definition of tenant, the meaning of the word Tenant:
Is tenant a scrabble word? Yes!
- n. - Someone who pays rent to use land or a building or a car that is owned by someone else
- n. - A holder of buildings or lands by any kind of title (as ownership or lease)
- n. - Any occupant who dwells in a place
- v. - Occupy as a tenant
Tenant is worth 6 points in Scrabble, and 8 points in Words with Friends
There are 6 letters in tenant: A E N N T T
Words that can be created with an extra letter added to tenant:
31 words found using the letters in "Tenant"
5 Letter Words
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Two 60ml bottles (120ml total) of E Liquid.
Bottles are squeezable and have child-resistant tamper-evident caps and non-metal dropper tips for easy refilling of your device.
Blended using an even 50/50 (PG/VG) mix to produce the perfect balance of flavour and throat hit. A 50/50 blend produces slightly less clouds than higher VG blends and the increased PG ratio strengthens the flavour.
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Concerned about cheap and harmful ingredients? Don't be! Reload E Liquid is manufactured using only high grade raw materials and pharmaceutical grade ingredients along with approved flavourings specifically made for use in e liquids.


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Physical medicine and rehabilitation, or rehabilitation medicine, is a complex course that focuses on enhancing and restoring the quality of life and functional ability of individuals suffering from physical disabilities affecting mostly the tendons, muscles, bones, spinal cord, and brain. To get accepted to a residency relating to physical medicine, it is vital to have a PM&R residency personal statement. It is possible thanks to an effective residency personal statement.
Individuals that have completed training in this field are popularly known as physiatrists or rehabilitation specialists. Unlike the majority of medical fields that focus on finding a cure, the purpose of physical medicine and rehabilitation is to help patients increase their independence when it comes to day-to-day activities and to improve the quality of their life.
Physical Medicine Rehabilitation Specialists
The main function of rehab physicians and specialists is to determine and treat disorders that need physiotherapy for occupational, mental, or physical rehabilitation.
- In standard hospital settings, it is the job of rehab physicians to provide residents and interns with instructions relating to the treatment of permanent or temporary disability conditions.
- A rehab physician first determines the characteristics of the patient, such as the duration, location, and intensity of the pain, using homogeneous clinical procedures.
- Examiners may also have a look at other factors, such as the patient's cognition, communication, strength, and mobility. Once these various factors have been assessed, a physician then documents the results and comes up with effective treatment strategies.
- Physicians also play a pivotal role in the lives of athletes, as they also determine and treat different sports-related injuries.
A physician's regular day looks something like this:
- Providing interns and residents with training.
- Checking the condition of patients and determining the right treatment.
Requirements to Become a Rehabilitation Specialist
Given the fact that physical therapists deal with a variety of functional problems, they must take their studies very seriously.
- A highly-dependable rehabilitation specialist is required to have at least a master's program in physical therapy that can take about 2-3 years to be completed.
- In addition to that, they also need to have a stellar PM&R personal statement.
- The curriculum normally handles subjects relating to musculoskeletal disorders, pharmacology, and neurology.
- Students are also required to rack up a decent number of clinical hours via residencies and internships.
- In terms of certification requirements, any student willing to become a physical therapist needs to ace the National Physical Therapy Exam (NPTE).
- If that's not enough, an applicant must pass a standardized national license examination by the American Academy of Physical Medicine and Rehabilitation (AAPM&R) Annual Assembly.
Here are some of the skills that one needs so as to confidently enter the world of physical medicine on a scale of 1 to 5:
|Experience Level
|Reading Comprehension
|Learning strategies
|Critical thinking
|Working as a member of a health services team
|Planning healthcare treatments
|Operating medical diagnostic equipment
|Giving healthcare instructions
|Time Management
|Complex problem solving
Top 5 Universities with Physical Medicine and Rehabilitation Residency Programs
To ensure that aspiring rehab specialists gain the best education, here is a list of the top rehabilitation residency programs that a student can apply for. Make sure you have a great physical medicine and rehabilitation personal statement when applying for them:
- This residency program is committed to restoring and enhancing the functional abilities of individuals who suffer from disabilities and physical impairments, teaching students to provide high-quality patient care, comprehensive education, clinical research, and innovative basic science.
- Thanks to state-of-the-art translational, clinical, and laboratory research, the university's faculty is at the forefront of groundbreaking treatments.
- Additionally, the university provides interns, fellows, and residents who have an interest in rehabilitation medicine with the best training programs.
- The goal is to achieve a higher quality of life by assisting patients with reaching goals in terms of improved individual care.
- The Department of Physical Medicine and Rehabilitation in the College of Medicine at the university is dedicated to delivering quality education.
- Thanks to this institution, many students are given the opportunity to hone their skills in different facets of physical rehabilitation, including neuromuscular disorders, geriatrics, strokes, brain injuries, spinal cord injuries, amputation, and medical disorders.
- The program aims to train physiatrists for comprehensive inpatient and outpatient rehabilitation, as well as to enhance their comprehension of clinical research.
- It is one of the most fundamental residency programs in America and the only honorary program based in Arizona.
- Thanks to the partnership between the Phoenix VA Health Care System, HonorHealth, and Select Medical, the residents will be able to participate in training in the following institutions:
- Phoenix Children's Hospital
- Carl T. Hayden Veterans Affairs Medical Center
- HonorHealth Rehabilitation Hospitals
- This physical medicine and rehabilitation service deals with the treatment, evaluation, and diagnostics of patients suffering from limited functionality that has resulted in impairment, injury, or consequence of debilitating diseases.
- This program helps students to focus their energy on the maximum improvement of the vocational, psychological, social, and physical functions of individuals, health maintenance, elimination of secondary complications, and alleviating pain.
- It is one of the top residency programs in physical medicine in the United States. Its main mission is to teach students advanced physical medicine and rehabilitation by doing clinical, translational, and innovation research in basic science.
- Additionally, the institution aims at educating staff, fellows, residents, and medical students on the requirements of effective medical rehabilitation and creating an ideal environment for comprehensive learning.
Major Components of a PM&R Residency Application
To ensure that your physical medicine residency application will be a success, here are some of the vital components:
- Complete application. Ensure that you have completed all the elements of your application
- Physical medicine and rehabilitation personal statement. It refers to information as to why you have chosen to apply for physical medicine and rehabilitation
- Recent photograph. A high-quality photograph of your face
- CV for residency. An up-to-date copy of your current CV
- 3 letters of recommendation. These are letters of recommendation from faculty members of your previous institutions. They should be original and written at least in the past six months
- Medical school transcript
- USMLE. Detailed USMLE results that focus on your physical exam results and clinical skills
- ECFMG. It should be part of foreign graduate students' applications
Writing a Winning PM&R Personal Statement: Difficulties to Know
Because of the complexity of a PM&R personal statement, there are some major difficulties that students face on a regular basis. Some of them include:
- Sugarcoating your story. Creativity is a plus when it comes to writing your residency personal statement physical medicine and rehab, but it is vital that your writing does not seem artificial. You will not impress the recruitment board with a PM&R personal statement including over-the-top descriptions that doesn't sound believable.
- Writing in a joking manner. Many students' common misconception is that they think that thanks to their excellent grades, they shouldn't put much effort into this part of the application. As a matter of fact, the majority of admission officials can easily detect a lackluster residency personal statement and then leave the student no chance.
- Irrelevant content. The word "personal" refers to your inner self. That's not where you have to list down all your extracurricular activities or all the achievements that you have made throughout your life, the things that a CV should contain. Make it about your story, not achievements.
- Not proofreading. Many students do not proofread a personal statement before submitting it. No matter how tired you are after diligently writing your personal statement, make sure you proofread it.
Physical Medicine and Rehabilitation Personal Statement Writing Tips
Here are the top 5 tips for writing a brilliant rehabilitation personal statement:
- Make your paragraphs brief and thus readable. There is something captivating about short paragraphs that make content just easier to read. The key to short paragraphs is making your sentences as short as possible. You need to make sure that your sentences are not longer than 20 words.
- Work on the flow of your personal statement. In writing, a good flow is everything. The parts of your personal statement should be connected. It is possible when you adhere to simple language. The less specialized vocabulary you use, the easier it is to understand.
- Keep your personal statement short. Overall, a personal statement should not feel like a dissertation. As a rule, it has to contain about 600 words.
- Outline your personal statement. Normally, a personal statement contains the introduction, body, and conclusion. It is the standard structure that you should follow.
- Proofread the content. Once you have completed your personal statement, take at least 30 minutes to go through it twice to ensure that grammar and flow are perfect.
Obstacles to writing a PM&R Residency Personal Statement
When applying for a PM&R residency, here are some things to look out for if you feel you are losing the flow of writing:
- Overconfidence: Being too confident of your personal statement will make you procrastinate, and you can end up writing it in the last minutes.
- Lack of purpose. In brief, if you do not put your heart into writing, you will probably not compose an ideal personal statement.
- Lazy writing. Lazy writing is when you write while being distracted by another activity. If this is the case, it is advisable to put off composing your personal statement and do it when you're not distracted.
What Are Some of the Services We Provide?
As our goal is to satisfy our clients, here are some of the key elements we focus on:
- Writing. We give quintessential writing help by ensuring that we create a fabulous personal statement based on the vital information that you have provided us with.
- Editing. Apart from writing, there are also editing features which include counter-checking whether we have met all the requirements you outlined for our writing team.
- Proofreading. We check the content to ensure there are no plagiarism or grammar mistakes!
Our various features enable us to handle a number of documents relating to a physical medicine application as follows:
- Personal statement. It is one of our main priorities. We ensure the application process is seamless with a superb personal statement.
- Admissions essay. It is a detailed essay that is crafted to boost your chances of acceptance to the residency program.
- Resumes. Resumes are written to help qualified physicians get a job in the field of physical medicine.
Choosing Our Physical Medicine Personal Statement Service
Here are some benefits of our physical medicine writing company:
- On-time delivery. We strive to deliver orders prior to the deadline date.
- Confidentiality. No personal information will be available for third parties.
- Zero plagiarism. Content delivered will be unique and plagiarism-free.


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Japanese electronics manufacturer, Sharp Corporation, has unveiled its new plan to launch a Blu-ray high-definition DVD recorder with a 1-terabyte hard disk drive (HDD) – the world's largest storage capacity of any Blu-ray recorder so far. With 1-terabyte hard disk drive, the recorder is able to record 127 hours of high-definition digital programming into a single hard disk drive. Prior to Sharp's 1TB recorder, Toshiba has also offered its HD DVD recorder which features the same amount of storage in June.
This huge storage Blu-ray recorder will go on sale tentatively in early December in Japan. The selling price for this model will be fixed around $2,616. Besides this model, Sharp Corp also highlighted that it will offer another eight new models of Blu-ray recorder by the end of the year in Japan in a bid to replace video cassette recorders and conventional DVD machines.


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An interesting article by Ravi Balakrishnan with ETBrandEquity. He interviewed Landor CEO Landor India to get a deeper insight into the new model for brand management and why building brand communities are so important.
The new model aims at involving all stakeholders in brand management and not assuming all forms of brand expression are equal
Landor's CEO Lois Jacobs says "Agility and adaptability are now top predictors of success, giving way to more audiences participating in how a brand is expressed and experienced." We spoke to Landor India CEO for a deeper insight into how this model works and what it will entail.
Some key highlights:
1. Why the Brand Community Model? What were some of the trends and insights that led to the development of this model?
The Brand Community Model resulted directly from the Agility Paradox, the research study we launched just over a year ago examining the common factors shared by the world's most successful brands. We found that agility is a key success indicator, and six behaviors in turn influence whether a brand can be considered agile.
But when it came to actually putting agility into practice, many brand managers and clients were struggling. Traditionally, brand management protocols have espoused a very rigid, command-and-control approach. All decisions were considered equal, all touchpoints were considered equal, and brand managers were expected to oversee everything. In today's world, brands have more channels, expressions, and audiences influencing them than ever before. It became clear that the old toolkit for was failing brand managers because it didn't account for this new environment. But there wasn't a clear path forward.
We spent the last year examining the intersection of agility and brand governance—interviewing over 20 Fortune 500 companies and numerous other industry insiders—to identify best practices in managing brands in an adaptive, agile way. The goal was to figure out how brand managers could have the influence and impact they need, but in a practical, flexible manner that makes sense for modern brands and consumers.
2. The model presupposes a high degree of consumer involvement with brands, considering the importance of superfans. Does this essentially restrict the model to categories where this actually happens and leave categories where the level of engagement is not as pronounced out of its purview?
The short answer: No. Superfans and fan involvement can be a part of the equation, but as you can see in our framework, they're actually only included in the Practitioner community (the Expert and Employee communities focus on internal groups and third-party agencies).
The specific audiences that make up each community will be bespoke for every individual brand based on their product, business model, and objectives. For example, many B2B businesses may find that superfans are a very small piece of the puzzle and that sales representatives, account managers, or social teams make up the brunt of their Practitioner community.
3. Have you begun to use the model/discuss it with current or new clients? What are the most favorable responses? What are the most commonly expressed misgivings?
Every day it seems like we enter into more conversations about how to flexibly manage brands today. We're involved in multiple engagements already to help clients implement this model, and we've seen that for most of them, the process of defining communities, determining brand expressions, and identifying goals helps to clarify their brand.
The most common misgiving is that it's a very uncomfortable shift for many brand managers, who have long held to the tenets of rigid control and authority. Some clients still fear that having more flexibility in the brand guidelines and giving away even a lit bit of control may cause a lot of harm. Trusting your brand's communities to properly represent the brand can be scary, but it is the most critical step in activating a brand in a dynamic, flexible way.
4. How collaborative was the process of coming up with this approach. Was this new process informed by any of your experiences in India that you'd like to elaborate on?
Many of our Indian clients do recognise that the old approach was restrictive in engaging all audiences with the right level of detail. For example, practitioners were being fed technical details beyond what was relevant and the focus was on the 'what' and not the 'why.' We were already starting to talk about a more layered approach to getting different parts of the organisation and external partners to understand and represent the brand. Though we had developed some ideas around agile brand management before our interviews with clients and the panel discussion in New York, we really solidified our thinking through those conversations—bouncing ideas off brand leaders from some of the world's largest global companies like GE and FedEx. This collaboration enabled us to create the framework and build our approach to brand expressions and the actions for brand managers.
5. Brand expressions here have been divided here into Sacred, Interpretative and Exploratory. Isn't this a little hard to determine at a time when brands, under a state of flux, make seismic fundamental changes to both their expressions themselves and how they express themselves? Or is this a way to keep certain elements permanent while changing the rest?
Though it's true that defining expressions by these three categories can be difficult, it is a very strong way to determine what a brand holds as fundamental to its core identity. We actually have a new tool—The Sacred Brand Expression Evaluator—to help companies do just this.
By segmenting different brand expressions, brands can ensure that as they adapt and change, their consumers still know what the brand represents. This was one of the most critical elements from the Agility Paradox: the importance of maintaining core principles while adapting to stay ahead of trends. By distilling brand expressions into the Sacred, the Interpretative, and the Exploratory, brands can strike the right equilibrium. They have the freedom to experiment with certain elements and involve diverse communities, without the fear of abandoning their heritage or misrepresenting their brand.
You can read full article here.


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"Francis can no more ordain women than he could baptize ducks or dead people."
As the highly questionable Amazon Synod thankfully comes to a merciful end, many are asking if Francis will now authorize the ordination of women as deaconesses (Holy Orders). I recall reading of deaconesses once long ago and far away. Continue reading "Francis and the Myth That He Can Ordain Women"


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Beverage Warehouse 4935 Mc Connell Ave #21, Los Angeles, CA 90066 (310) 306-2822 FAX (310) 821-4555
|Le Colombier's 2007 Vacqueyras Vieilles Vignes, composed of old vine Grenache (80%) and Mourvedre (20%), is fermented and aged in concrete vats in order to preserve the fruit. The dark red fruit flavors show exceptional ripeness and amazing depth, and the wine dazzles with "powerful aromas of blackcurrant, dark cherry and tobacco, plus a subtle hint of black pepper." Josh Raynolds, Stephen Tanzer's International Wine Cellar, January 2009. "The wine is powerful, pure, layered, and altogether a brilliant example of Vacqueyras that should drink nicely for 6-8 years." Robert Parker, Wine Advocate, October 2009
|Last Updated:
|2012-05-03 14:08:59


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If you are looking for a new and rewarding career for 2020, then we could have what you are looking for. Do you have an unfulfilling job role that you want to swap for a job for life? Maybe you are retired/semi-retired, and you are looking for a role where you can give something back? A role where you can make a positive difference to the life of an older person living in your local community? If so, then becoming one of our Paid Volunteer, Befriender & Companions could be perfect for you.
We have opportunities to do something amazing and become a part time Paid Volunteer, Befriender & Companion in the Ongar, Epping, Loughton, Waltham Abbey, Harlow and surrounding areas of Essex. No experience is required as excellent training is provided. You could be part of something to be proud of like this:
"My Nana was diagnosed with early onset Dementia earlier this year and the word immediately frightened me. Nan has lived on her own for a few years since my Grandad passed away but has always been independent, so this diagnosis worried me that she would no longer stay living in the place that holds all her memories and where she spent over 50 years with Grandad.
However, Nan has had wonderful companionship, care and support from people she has grown so fond of, we as a family have more peace of mind as we know she's not alone. She has been able to keep getting out and about doing the things she loves, including visiting her local music group, and most importantly you have allowed her to keep being herself in the home that she loves. The personal care received has been respectful and dignified. Thank you will never be enough."
Be part of something special
We are an award-winning national brand who focus on a companionship led care service. We have won multiple awards over the years and have built an excellent reputation within communities across the UK. They are rated "Outstanding" by the CQC which is amazing. The owner moved into the care sector to do something that she could be proud of and make a difference in the local community, creating a high-quality bespoke service that would allow older adults to live independently in their own home for as long as possible.
Pay rates, hours & benefits
- Contracts available include –
- 16 hours per week contract- £8568 per annum - 0700-1030 every day or 0815-1315 every day -Alternate weekends required.
- 20 hours per week contract- £10,701 per annum - 0815-1315 every day or 1700-2200. Alternate weekends required.
- 26 hours per week- 0815-1315 and 1645-1900 and alternate weekends.
- 30 hours per week contract- £15,990 per annum. Availability 0815-1315 (break) and 1700-1915. Alternate weekends. OR availability 0930-1315 (break) and 1700-2030.
- 40 hours per week contract - £21,320 per annum (limited availability).
- We actively promote from within, so there are fantastic opportunities for ongoing progression for the right person.
- Making a difference to someone's everyday life is the biggest benefit and motivator for doing this job, along with building lasting relationships.
If you feel you have the qualities to do this Paid Volunteer, Befriender & Companion role, then we would love to hear from you. We are proud to advertise on behalf of this unique provider and welcome your applications. Once you apply, we will arrange a suitable time to discuss the vacancy in more detail and answer any questions you may have.
** PLEASE NOTE this is not a Volunteer job, it is paid employment, however we are trying to attract those that would look for Volunteer type jobs.


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One Way taxi from Aurangabad To Ajanta And Ellora Caves car. Book One Way taxi. Car fares & check for online discounts & deals on Aurangabad To Ajanta And Ellora Caves car taxi service.? No Extra-Charges. Call 8888807783. Aurangabad is a city in Maharashtra state, in India. It's known for the 17th-century marble Bibi ka Maqbara shrine, styled on the Taj Mahal. The nearby Shivaji Maharaj Museum, dedicated to the Maratha king Shivaji, displays war weapons and a coin collection. North of the city, the Aurangabad Caves comprise ancient, rock-cut Buddhist shrines. West of the city, battlements surround the medieval Daulatabad Fort.
Ellora (\e-ˈlȯr-ə\, IAST: Vērūḷ) is a UNESCO World Heritage Site located in the Aurangabad district of Maharashtra, India. It is one of the largest rock-cut monastery-temple cave complexes in the world, featuring Buddhist, Hindu and Jain monuments, and artwork, dating from the 600–1000 CE period. The Ajanta Caves are 30 (approximately) rock-cut Buddhist cave monuments which date from the 2nd century BCE to about 480 CE in Aurangabad district of Maharashtra state of India.
Distance between Aurangabad To Ajanta And Ellora Caves is 102.5 km by Road along with an aerial distance. The Distance can be covered in about 03 hours 17 minutes by Aurangabad To Ajanta And Ellora Caves cab. Your Ajanta And Ellora Caves travel time may vary due to your bus speed, train speed or depending upon the vehicle you use.
When renting a car for rent car for Aurangabad To Ajanta And Ellora Caves, its best to book at least 1-2 weeks ahead so you can get the best prices for a quality service. Last minute rentals are always expensive and there is a high chance that service would be compromised as even the taxi provider is limited to whatever vehicle is available at their disposal.
June to March are the best months to visit Ajanta and Ellora Caves. It becomes a little difficult to travel around and explore the caves in summers April-May.
Car On Rentals provides One Way Car Rental from hire taxi from Aurangabad To Ajanta And Ellora Caves, which includes the pick from anywhere in Aurangabad including city / Aurangabad and drop off To Ajanta And Ellora Caves City. We provide instant confirmation and flexibility to book 24x7.One Way Taxi from hire cab from Aurangabad To Ajanta And Ellora Caves is the best option for travelers who would like to travel One Way only from rent taxi from Aurangabad To Ajanta And Ellora Caves would easily pick you up and drop you at your preferred location anywhere in Ajanta And Ellora Caves. It is not a shared Cab. It will be a dedicated cab for you.
When you rent a car from Aurangabad To Ajanta And Ellora Caves taxi services, we'll help you pick from a range of car rental options in Aurangabad . Whether you're looking for budget cars, comfortable cars, large cars or a luxury car for your trip- we have it all.We also provide Tempo Travelers for large groups. Aurangabad To Ajanta And Ellora Caves car hire,You can choose between an Indica, Sedan, Innova or luxury cars like Corolla or Mercedes depending on the duration of your trip and group size.
|Cab Type
|Min KM
|Hatchback- Ritz / Indica /Similar
|Sedan- Etios / DZire / Similar
|SUV - Innova / Xylo / Enjoy /Ertiga / Similar
|Force Tempo -12 Seater
|Force Tempo -17 Seater


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BRUW Filter: Filter Your Cold Coffee Without Any Mess
Discover Another Product | I Want This!
BRUW is the newest way to make cold brew at home! rather than learn a brand new method, make it in mason jars like you've always been doing! simply prepare your cold brew coffee in a mason jar and use the BRUW filter to filter it. Easily make your own cold brew coffee at home. This filter makes brewing easy, just put it on a wide-mouth mason jar.
It's super easy. Let coffee grounds brew in a cold-water-filled mason jar for around 12-24 hours. When you're ready to drink some BRUW, twist the filter onto that jar with the straw side down. Then twist the second mason jar on top of the filter. Flip it, and watch your cold brew filter through.
If you're not used to cold brew, it's smoother, less acidic, and it's easier on your stomach than coffee brewed with hot water. Less acidity also means you can better taste all the subtle flavors—like traces of chocolate, fruit, and nut inherent in different beans.
About The Product
– Durable, injection molded, plastic construction
– Stainless steel filter
– Includes two wide mouth ball mason jars
We Support #ZeroHunger
There's enough food in the world to feed every man, woman and child. Yet, there are more hungry people than the populations of the United States, Canada and EU combined.
The World Food Programme, along with many other partners, are working to solve this moral challenge.
With your generous support, families can share meals together, life-saving nourishment can be provided to those affected by conflict, and students can thrive at school thanks to a daily school meal.
*Donations are processed directly by the World Food Programme and do not go through SocioSpree. Please do not address donations to SocioSpree.(Source)
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Your search did not match any results.
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Why Are We Building This?
Analytics don't live in isolation. They fuel every insight, personalize millions of interactions, and power business processes throughout the organization. Being able to take action—in context—directly from your analysis enables you to streamline the insight-to-action continuum.
Most analytics systems limit insights to facts. Sharing them and taking action is up to you. With the action framework, you'll be able to specify a number of actions that can be performed, simply by right-clicking. Select a row in the answer set or a dot on a scatterplot and link to an action. If a customer is identified as at risk of leaving, you can right-click and begin an activity, such as alert the sales manager, issue a service ticket, and/or call the customer directly.
Actions will be enabled directly from Oracle Analytics to any process you choose. These connections to supporting business systems tighten the bond that connects insight discovery to taking action.
The preceding is intended to outline our general product direction. It is intended for informational purposes only, and may not be incorporated into any contract. It is not a commitment to deliver any material, code, or functionality, and should not be relied upon in making purchasing decisions. The development, release, timing, and pricing of any features or functionality described for Oracle's products may change and remains at the sole discretion of Oracle Corporation.


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How to travel from Naples to sorrento
Looking for best way to travel from Naples airport to sorrento.
6 Answers
Get to naples train station walk downstairs and take the local train down...be extremely careful of your valuables keep your wallets locked in luggage that is padlocked...naples trains are the worst place for thieves and pickpockets almost 7 years agoAnswered by Mathew F via Ask a Nomad iPad app
Ditto Matthew F. You don't have to wait at the large ticket boxes but go down the escalator and buy your ticket there. Do watch you bags though. I'm soooo careful, have different purses with everything zipped in over shoulder bags etc and my purse was stolen with all my cards and £'s. But, having said all that, thoroughly enjoyed Naples and Sorrento so have a great trip. You can get a bus back to the airport from Sorrento outside the train station for approx €10 each. almost 7 years agoAnswered by Elsa via Ask a Nomad iPad app
Thank you for your help. I heard something about possibly taking a ferry? Do you know anything about this? almost 7 years agoAnswered by Alisandrina via Ask a Nomad iPad app
Here's everything you need to know about getting from Naples to Sorrento. Definitely heed the advice to watch your belongings along the way. I've been approached by everything from pickpockets to a guy who offered to sell me the machine gun he had under his jacket on the docks at Naples. While you're there, you might as well go to Capri. Take the excursion to see the "Blue Grotto" and the beautiful town. . it's well worth the time. Have a fun trip! almost 7 years agoAnswered by Gerry - Virginia USA via Ask a Nomad iPad app
Of course I forgot to add the travel link with the in formation you need my apologies!
http://www.sorrento-online.com/english/orari.htm almost 7 years agoAnswered by Gerry - Virginia USA via Ask a Nomad iPad app
Don't bother going to Capri to see the Blue Grotto. It's a big tourist ripoff. It's run by the mafia. They cater first to whatever boat they see carrying Asians, as Asians are supposedly bigger tippers (especially when the row boat drivers threaten not to take them back to their ship). For the two minutes inside and the three boat fees (one way) it's a costly trip and you run the risk of falling to/from the row boat. If you're a smaller framed person the rowboat driver will squeeze another person in between the already tight space in order to make one less trip into the grotto. about 4 years agoAnswered by Rose via WorldNomads.com


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We were going to the store to buy a few things so we got dressed fairly quickly and as you can tell I threw my hair up into this huge bun. Which has been my summer go to hair style. Quick and easy and actually surprisingly looks pretty put together- can't beat that as an on the go mommy look. Going to the store is a kind of a big deal to Shane and I. If you don't get out of our town you start to feel trapped. So little trips to the grocery store save us.
Daddy was kind enough to take some photos of us. He is becoming a really good photographer.
Me and my girly wirly!
Her eyes look so much like her daddies. Love.
These shorts of Amelia's are my go to bottoms for her right now.
She is such a happy toddler! Daddy helped her "pose", but she
brought the smile all by herself.
It doesn't get any better then seeing Shane be so sweet with our baby girl.
This smile tho. : )
Daddy is her first love! She has him wrapped around her finger. Watch out!
Sleeping pictures of Amelia are some of my favorites. It makes me think of her as a newborn when she would sleep so much and cuddle with me all day.


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Meet David Flench
David Flench serves as a board member of the Medical Fitness Association Board of Directors. When he's not working with MFA, David can be found at Hancock Regional Hospital leading the Wellness Centers and Outpatient Diabetes Education Center as the center director. David's main focus is on the development of clinically-integrated programs, strategic planning, outcome measurement, and operational oversight. He has guided both facilities to successfully achieve designation as certified medical fitness centers.
David has over 20 years of experience working in the health and wellness industry. Previously, David was general manager of the Sarasota Memorial Healthplex, director of Mariners Wellness Center, and fitness manager at the McConnell Heart Health Center.
David obtained his Master of Business Administration from Franklin University in Columbus, Ohio and his Bachelor of Science with a concentration in Exercise Science from The Ohio State University in Columbus, Ohio. He also has achieved a range of certifications including Six Sigma Green Belt, American College of Sports Medicine Certified Exercise Physiologist (ACSM-cEP), and ACSM Level 2 Exercise in Medicine demonstrating that he is committed to furthering the medical fitness industry.
David is an active member of the Rotary Club of Greenfield, as well as graduate of both the Sarasota County and Hancock County Leadership programs. When he is not at the office, David can be found coaching several of local youth sports teams for his two boys.


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Company Overview
About Us
We started as a trading business named Yew Lee Machinery in 1992 with primary business of trading machinery hardware and industrial brushes. Throughout the years, the business opportunities grew by the overwhelming support and demand from customer.
Thence, Yew Lee Pacific Manufacturer Sdn. Bhd. was established in 2004 to started own manufacturing products with the enthusiasm of provide the best service and quality products to our valuable customers.
We are specialize in latex dipping industry through years of collaboration with the engineers on providing ideas and solutions for efficiency and quality enhancement in production process. With the needs of market, continuous investment and improvement to be carry on along the years in order to support customer requirement. We also provide a wide range of diverse industrial brushes and household brushes from locally to worldwide for all kind of industries.
Corporate Policy
To be the leading brush manufacturer by establish branches at worldwide to providing cost effective solutions and trustworthy services for our business partner.
We are committed to provide our customers with excellent quality products and services by execute continuous improvement through training, research and development.
Core Values
Core values are the fundamental beliefs of a person or organization. These guiding principles dictate behavior and can help people understand the difference between right and wrong. Core values also help companies to determine if they are on the right path and fulfilling their goals by creating an unwavering guide, therefore we make it as SIMPLE as possible for better understanding.
- Satisfaction
- Improvement
- Modesty
- Persistence
- Learning
- Ethical
Our Motto
You Require-We Deliver. That's our motto and we stand behind it in order to move forward to become the one stop leading brushes manufacturer in Malaysia specialize in custom brush solutions. Our team will present you the best solutions for your specific application through our ongoing commitment to quality and service.


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Dining, Entertaining and Living
126 products
Ever walk through the stores on a Main Street and to walk into a shop and see a beautiful table and chairs carved and finished by a local woodworker, and atop that set table are locally made service pieces meticulously painted, local linens, handwoven placements?
Here you'll find mostly unique items offered by local merchants, and certainly some branded tumblers and local treasures like glassware and dishtowels.
Showing 1 - 24 of 126 products
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How the major US stock indexes fared on Tuesday
U.S. stocks and Treasury prices plunged Tuesday after Federal Reserve policymakers said they were worried about a slowdown in hiring and appeared to resist buying more bonds to help the economy.
The Dow Jones industrial average closed down 64.94 points, or 0.5 percent, at 13,199.55.
The Standard & Poor's 500 index finished down 5.66, or 0.4 percent, at 1,413.38.
The Nasdaq composite index lost 6.13, or 0.2 percent, to 3,113.57.
For the week so far:
The Dow is down 12.49 points, or 0.1 percent.
The S&P 500 is up 4.91, or 0.3 percent.
The Nasdaq is up 22, or 0.7 percent.
For the year so far:
The Dow is up 981.99 points, or 8 percent.
The S&P 500 is up 155.78, or 12.4 percent.
The Nasdaq is up 508.42, or 19.5 percent.


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Builders' Forum Archives
Re: Why not?
Posted by LeeG on Sep 28, 2005
what's your experience with the swiveling tabs to determine there needs to be something better?
Webbing and fasteck buckckles require substantial finger strength to seal well. If one breaks in a rescue you're 1/2 way to seriously comprising flotation. Webbing and fasteck buckles don't work well on flat aft decks.
Hidden bungies under the deck require dexterity. Try it with gloves or bare hands in 45 degree water/wind. The hidden lever device shown looks cool,,and reduces failure safety to two bungies.
With the flip levers you can see if it's working or not. There's redundancy according to the number of levers ,,six is good.
In Response to: Why not? by Mike D on Sep 28, 2005
- Re: Why not? by Mike D on Sep 28, 2005


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Mauritius is the natural choice for families seeking an idyllic island getaway. And with its picture-perfect beaches, wide selection of activities and family-orientated accommodation, it's not hard to see why. Lying in the sun-drenched Indian Ocean, Mauritius is just a short flight from Cape Town, Durban and Johannesburg, so you can easily pair your Mauritius family vacation with a trip to family-friendly South Africa.
Tour & Safari
Family KwaZulu-Natal & Mauritius
From $5,750 per person sharing
Destinations visited:
- KwaZulu-Natal
- Mauritius
- South Africa


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John Harker, the society's area officer for Sheffield contacted Sheffield Council earlier this year about a problem on Bradfield Footpath 93. John's comments were:
There is a wet patch where an old metal drainage pipe crosses the footpath at SK 2638 9303 The pipe is clearly inadequate for the job. The wet area is wide enough to be awkward for the less agile & elderly. Can a new pipe be put in & covered over.
The society is delighted to report that the council's public rights of way unit have resolved the problem. Before and after photographs are shown below:
This path is particularly important to PNFS as it has 2 of our Society signposts on it further along towards Rocher Head, see below:


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My mom came home and had a heart attack because I didn't go to skool, and then we had to go to this therapy appointment that we booked like a month ago. I thought it would be all wood, but I was very wrong.
It was the most brutal session of my life.
She dug up so many details from my past that I wanted desperately to forget, or to at least think that I had forgotten, but they all came at me like someone had opened a flood-gate. I cried in front of this woman, and made my mother cry, calling back everything that was wrong almost ten years ago, whose visions are still crystal in my memory, and feeling stupid for being so haunted at the age of seventeen.
People can have ghosts at any age, given the circumstances.
Yesterday I thought I had finally come to terms with my ghosts, but today I was thrust into a dark room full of them, and I realise now, I am ready for nothing.


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News and Commentary on Affirmative Action, Equal Opportunity, Civil Rights and Diversity - Brought to you by the American Association for Access, Equity, and Diversity (AAAED)
The U.S. Department of Justice has found that the University of New Mexico violates federal law in how it responds to reports of sexual harassment and assault, the department said on Friday in a news release.
Read the story here.
Post a Comment


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Summary: This article will tells a simple and reliable way to restore the deleted and lost photos, pictures and more from your Samsung Galaxy A60 even if without backup.
Samsung Galaxy A60 has many bright spots, such as 6.3-inch screen, screen vibration and sound technology, Snapdragon 675 processor, 3500 mAh battery, 15W fast charge, Android One UI system, rear-three-camera (32MP main camera, 5MP virtual camera, 8MP ultra-wide-angle camera), full-featured NFC. More importantly, its price is not high. I think Samsung Galaxy A60 has a high cost performance, and its actual experience is also very good.
Last week, I traveled with my family. I took many beautiful photos with Samsung Galaxy A60, which made me very satisfied. But my little daughter picked up my Samsung Galaxy A60 while I wasn't paying attention. The end result was that she scrambled on my phone and all the data was deleted. Because my Samsung Galaxy A60 is still a new phone, there is not much data stored in phone. But those beautiful photos have been deleted. I want to restore them.
Here, you need a professional data recovery software, and Android Data Recovery is your best choice. On the one hand, the software is so compatible that supports many Android models like Huawei, Samsung, HTC, LG, Xiaomi, Sony, Google, vivo, OPPO and many more. On the other hand, it can recover almost all data including photos, SMS, WhatsApp messages, contacts, videos, audio, call history, documents etc.. In addition, the software will not delete or modify any data in the mobile phone when restoring data. The whole recovery process is safe and simple, and the steps are as follows.
Step 1. Download and Install the program on your computer with the above link accordingly. Once it is completed, it will automatically run. Connect your Samsung Galaxy A60 to the computer via a USB cable.
Step 2. Turn on USB debugging on your phone. If you don't know what to do, you can follow the instructions on the screen to open it. Then click "OK" to continue.
Step 3. Next, check the "Media", and select "Gallery" and "Picture library". When the selection is complete, click "Next".
Step 4. The program needs to get privilege to scan data from your phone. You should Allow/Authorize/Grant when it prompts on your phone screen.
If there is still no such pop-up window, please click "Retry" to try again.
Step 5. When the authorization is successful, the program will start scanning your phone data. The content you check here is all photos, so the scan results only include deleted photos. Next, choose which photos you want to restore and tick them, and click on "Recover" to save them back to your computer.
Note: Please make sure your Samsung Galaxy A60 is sufficient power and keep your phone well connected to the computer during the whole recovery process.
Related Tutorials:


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| 7.5°C Belfast
Police are appealing for witnesses following the report of hit and run RTC involving a quad and a pedestrian on the Erganagh Road in Omagh on Friday night.
Inspector Glen Latimer said: "Police attended the scene at approximately 10.45pm. The man had sustained serious head injuries and was receiving treatment from ambulance staff at the scene before being taken to hospital.
He continued: "I am appealing to anyone that may have witnessed any suspicious activity in the area at the time particularly regarding the movements of two quad motorbikes to contact Omagh Police Station on the non-emergency number 101, quoting reference 1438 of 07/07/17."
Alternatively, to give information anonymously, ring Crimestoppers on 0800 555 111.
The road has reopened.
Belfast Telegraph


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Appalachian Trail - Peck's Corner to Tricorner Knob
At A Glance
5.3 mi one-way
Difficulty Rating: 5.3
Steepness: Level
Tread Condition: Few Obstacles
This trail is located in the Great Smoky Mountains National Park area. For a list of all the trails in that area, see the Great Smoky Mountains National Park trails list page.
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text: Analytical and Quantitative Light Microscopy - MBL A comprehensive and intensive course in light microscopy for researchers in biology, medicine, and material sciences. This course provides a systematic and in-depth examination of the theory of image formation and application of video and digital methods for exploring subtle interactions between light and the specimen. This course emphasizes the quantitative issues that are critical to the proper interpretation of images obtained with modern wide-field and confocal microscopes. This course is limited to 32 students. May 4-13, 2011 Quantitative Fluorescence Microscopy This one week, intensive microscopy course will cover all aspects of the technology from the principals of fluorescence imaging to multidimensional imaging in living cells. Lectures dealing with the theory, mechanics, and application of fluorescent imaging methods will be intermingled with extended laboratory practicals in which students will be encouraged to use their own specimens, to optimize the utility of the course. Our goal will be to provide students with the knowledge and expertise to implement cutting edge microscopic methods within their own laboratories. May 20-27, 2011


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There was a time when bounce rate and average time on page were "nice to know" metrics. They showed up in your website analytics, but you probably paid far less attention to them than other SEO data points.
Times, they are a'changin'. Bounce rate and average time on page have valuable information to share with regard to website performance and user experience — and B2B marketers and web designers building and maintaining sites are paying close attention.
The question is not if or why bounce rate and average time on page metrics matter, but how to improve them on your site.
In this article we'll cover:
- What bounce rate and average time on page mean
- Ideal benchmarks for each
- Common causes of poor performance
- Tips to improve bounce rate (including a handy infographic)
What Do Bounce Rate and Average Time On Page Mean?
Hubspot's definition of bounce rate is, "the percentage of people who land on a page on your website and then leave without clicking on anything else or navigating to any other pages on your site." In practice, bounces look like this: Someone finds one of your blogs on a search engine results page (SERP), clicks through, reads the article, and then exits your site without visiting any other pages.
Average time on page is exactly as the name suggests — the average amount of time visitors spend on a particular page — and it reveals if they are actually reading your content. For instance, if the average time on page for a lengthy blog post is only 10 seconds, it's safe to assume that most visitors aren't actually reading the post.
What Are Good Numbers For Bounce Rate and Average Time On Page?
Many factors influence bounce rate and average time on page, such as what kind of traffic your site is attracting and the SEO that's been done.
The page type and the content it contains are also factors. If the page is largely informational without many links to other parts of your site, then a high bounce rate and low average time on page may not be too alarming. The opposite should hold true if the page is, for example, mainly a directory of links to your products and services.
What's an ideal average for time on page?
The truth is, ideal average for time on page will vary. Some marketers state that their average time on page is between 2-3 minutes. Others dial into this metric using read time, which is averaged based on the number of words in an article and a general reader's words per minute speed. In that scenario, a 40- to 50-second page visit is encouraging.
Target Bounce Rate Percentages
To get an idea of the variations in bounce rate, check out this graph created by Conversion XL showing the average bounce rate for various industry web pages.
Source: ConversionXL Bounce Rate Benchmarks
In general, you should aim for a bounce rate below 40%. If it's above 55%, you definitely need to look for reasons why people may be leaving your site and for ways to improve.
On the other hand, don't let an extremely low bounce rate lull you into a false sense of security. An average bounce rate of 20% or less might reflect really engaging content, but it's more likely an indication that there's something wrong with your site analytics tool, such as a duplicate tag.
4 Reasons Behind High Bounce Rate
- Mobile devices. You're probably among the 81% of adults in the U.S. who own a smartphone and know how difficult it can be to do extensive research on a small screen. People are likely to bounce sooner when using a mobile device rather than a computer or tablet.
- Popular blog posts. Blogs with high SERP rankings and social media shares attract a lot of traffic that want answers to specific questions. Once they've found those answers, most people bounce to other sites for additional perspectives.
- Some pages are more in-depth than others. A disproportionate amount of time may be spent on different pages, for various reasons. For example, pages with a single CTA are likely to have a much higher bounce rate than those offering multiple CTAs, links, and other similar in-depth content. Your landing pages should have very low bounce rates, since ideally visitors would be getting there from a CTA on your site, and taking another action on the page, such as filling out the form.
- Structural issues. If your bounce rate exceeds 70%, look at your pages from a visitor's perspective. Where is the user experience failing? Are there any obvious errors like 404 pages or content that doesn't align with meta descriptions?
My Metrics are Horrible! What Do I Do?
Don't panic, but do investigate how you can remedy a high bounce rate and/or low average time on page:
- Check your site's page-load speed. If you have a ton of large, high-resolution images, pages may take too long to load. People are impatient and will abandon pages with excessive load times.
- Make sure site navigation and page links are user-friendly. Your main site navigation menu should appear on every page except landing pages, and each page should link to related articles/content so users can dig deeper into your site, no matter what page they first enter through.
- Review for SEO. Use proper keywords, page meta descriptions and titles throughout your site.
RELATED: 7 Ways to Craft the Perfect Meta Descriptions that Convert
- Provide engaging (and relevant) content. It will help you see the largest improvements because visitors will be more likely to read what you have to offer. It's great to generate a large number of visitors, but if they aren't sticking around, you're missing opportunities to convert them to leads.
(More) Best Practices to Improve Bounce Rate
- Use short paragraphs and section headings to keep text easily digestible.
- Don't use pop-ups, they're annoying. If you can't help yourself, make them exit intent pop-ups. They appear when a visitor's cursor moves outside the upper page boundary (indicating their potential exit from the site), and are far less likely to cause bounce.
- Regularly write and repurpose blog content, advanced content, and press releases.
- Use keywords and long-tail keywords that prospects will organically search. Research tools like SEMrush or Ubersuggest are great resources for identifying appropriate keywords.
- Thoughtfully craft meta descriptions and calls-to-action (CTAs) to encourage clicks.
- Open external links in new tabs.
- Add video! Need inspiration or tips on making video happen? Check out our library of Video Marketing Resources
To help keep these tips top of mind, our friends at Easelly made this infographic summary:
Improving your website's bounce rate and average time on page will ultimately improve your SEO. Check out our SEO Survival Guide for even more ways to improve your SERP rankings and website performance.


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Interview with a Nerd
Geek Media and Culture: Explained.
We found 3 episodes of Interview with a Nerd with the tag "phoenix".
025: Phoenix: Resurrection with Darren Herczeg
February 28th, 2018 | 1 hr 34 mins
captain america, fresh start, jean grey, leah remini, marvel, persona 5, phoenix, troublemaker, van helsing, venomized, x-men, zenescope
This week Darren Herczeg joins to discuss the anticipated resurrection of Jean Grey AKA Phoenix
018: Penguins Vs Possums
September 20th, 2017 | 1 hr 27 mins
cocktail movie recap, destiny, fanbase press, image, it, marvel, penguins vs possums, phoenix, power rangers, pvp, rat queens, the big sick, tomb raider
The creative team of Penguins Vs Possums
016: Jean Grey with Darren Herczeg
August 23rd, 2017 | 1 hr 23 mins
child of light, coeur de pirate, jean grey, marvel, new mutants, phoenix
Darren Herczeg joins the show to talk all about Jean Grey


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Antima Abbamonte
(Milano, 26 Aprile 1967)
Cantante, autrice, arrangiatrice, produttrice e band leader, nota con il nome d'arte di Lupa. Nata in una famiglia di artisti da bambina ha lavorato come modella per Vogue Bambini e più tardi come attrice nella compagnia di Dario Fo' e sua moglie Franca Rame. Trasferitasi in Inghilterra a fine anni Ottanta, frequenta la Birmingham School of Speech and Drama e la London Academy of Music and Dramatic Arts. Vive a Birmingham, dove dal 1996 ha collaborato con vari musicisti, compositori, arrangiatori, produttori e tecnici del suono nell'ambito della musica pop e underground sulla scena inglese, spagnola ed americana incluso Bryan Corbett, Roberto Dell'Era, Alfonso Deidda e Roger Inniss. Ha inciso diversi cd con le sue musiche, fra cui spiccano l'album d'esordio"House of Blue" e "Lupa live at Symphony Hall", del 2006. Tra le sue composizioni: Notte & giorno, Luck & love, Farewell, If u close yr eyes.
Lupa pseudonim of Antima Abbamonte (born in Milan, 26th April 1967) singer, song-writer, arranger, producer and band leader. She moved to England at the end of the 80's, and attended the "Birmingham School of Speech and Drama" and the "London Academy of Music & Dramatics Arts". She has performances all over Europe working with various musicians like: Tom Hill, Roger Inniss, Mike Green, Ryan Trebilcock, Dave Storer, Trevor Lines, Peter Reed, Cornelius Wynter, Chriss Map, Charlie West, William French, Andy Hamilton.
Selected works: Notte & giorno; Luck and love; Farewell; If u close yr eyes.
Recordings: House of Blue; Lupa live at Symphony Hall, 2006.
Contact: www.lupamusic.com
Arienne Dorothea Agnoletto
(born in Poland, resident in Vienna).
Conductor, composer, violinist and pianist, and also holds a law degree. She has frequented courses for orchestra conductor in the Vienna Academy of Music, held by the Professor Karl Osterreicher, and in Mainz held by the carismatic Sergiu Celibidade. She has presented several concerts in different European countries, and in Japan, Korea, Usa and Mexico. She has been active internationally as a conductor since 1993. Agnoletto has collaborated with various orchestras and opera houses such as the Lviv Theater of opera and Ballet, Teatro Regio di Torino, The Silesian Opera and the Orchestra Femminile Europea (Milan). Since 1994, she has been principle conductor of the Philarmonica Gaudì Vienna, which has performed different concerts, tours ( Guanajato Festival during the Mexico Tournèe in 1996), and the Young Polish Philarmonic. Agnoletto is chairwoman of the Viennesse association Art in Action. She has been a member of OKB since 2001. Her first opera, Brahman (1996), was commissioned by the city of Cracow and written using an avant-garde composing technique that precisely transfers the mathemathical frequencies of the texts onto notes. Her children's opera Pinocchio (2001) was commissioned by the Comune di Vittorio Veneto from texts by the well-known Florentine poet and painter Dora Raparo Bianchi. She speaks six languages fluently.
Selected works Venus Hochzeit oder die Klage einer alten Frau aus Berlin for s, mime, tape and chamber orchestra, text: P. Sichrvsky, premiere: Philarmonia Gaudi Vienna, Haus der Musik ( Vienna 2000);Pinocchio, children's opera 2001, text: D.R. Bianchi, Teatr Korez ( Katowice 2003) ; Ave Maria for mixed choir, premièred by the Lviv Chamber Choir " Gloria", Ave Maria Festival ( Poland 2005); Brahman Opera, text: Malgorzata Stawarz 1997 commissioned by the city of Cracow, performed framm. 1998 Lvov, Ucraina Lvov Philarmonia.
Adaptation Alexander von Zemlinsky- II. Streichquartett- ad. for string orchestra 2000 reg. Cd prod Klangvolumen30000 Philarmonia.
Discography: I love Johann Strauss. Ursula Rojek singt die schönsten Operetten und Wiener Melodien, with Ursula Rojek, coloratura soprano and the Radio Symphony Orchestra Cracow (CD)
Tribute To Freud, soloist. Ingrid Haselberger, Philarmonia Gaudi Vienna (CD)
Ave Maria, Lviv Chamber Choir "Gloria" (CD)
Artemia Aifotitti
Composer, she was born in Nicosia, Cyprus, in 1986. She studied at City University, London, with Norman Beedie at the Guildhall School of Music and Drama (GSMD) and with Rhian Samuel. She graduated in June 2007 with a Bachelor of Music and continued with a Master of Arts in Instrumental and Vocal Composition at City University with Rhian Samuel. Her works have been performed by the prestigious London Sinfonietta, in well known venues in London such as LSO St. Luke's and The Warehouse, Waterloo. She was student ambassador for City University's Music department and School of Arts. She was composer in residence for the Cyprus Clarinet Studio (CCS) for the academic year 2008-2009 and secretary of The Friends of Arte Society. Since her return to Cyprus in 2008, she is active as a composer with performances in several events throughout Cyprus.


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Kings Of Leon 'Walls' tour is set to continue in 2017. First concert is scheduled at the Sleep Train Amphitheatre in Chula Vista, CA (nearby San Diego) on April 28. The tour will visit 25 cities of the North America. The final concert is scheduled for the Gorge Amphitheatre in Quincy, WA on August 26. Presale tickets for all Kings Of Leon concerts are available now at TicketsTeam.com, an online event tickets marketplace.
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"Even if WALLS doesn't live up to the marketing's promise of completely redefining Kings of Leon's sound, it at least finds them at ease with themselves," Consequence Of Sound's Dan Caffrey writes. "Although Mechanical Bull attempted the same thing after two albums' worth of public turmoil, there was still an onset of exhaustion, the sense of a family band who hadn't yet fully repaired their frayed relationships. But here, the Followills sound mature, relaxed, and locked in with one another. To put out their best album in years, they didn't have to tear the walls down, as the teaser suggested. They just had to take a breath and repaint them." Kings Of Leon fans, who already secured their seats through TicketsTeam.com for select concerts, will be part of great shows.
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July 29: Mohegan Sun Arena in Uncasville, CT;
August 1: Jones Beach Theater in Wantagh, NY;
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August 5: Lakeview Amphitheater in Syracuse, NY;
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August 9: Budweiser Stage in Toronto, ON;
August 11: Riverbend Music Center in Cincinnati, OH;
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August 16: Blossom Music Center in Cuyahoga Falls, OH;
August 18: KeyBank Pavilion in Burgettstown, PA (nearby Pittsburgh);
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August 24: Shoreline Amphitheatre in Mountain View, CA (nearby San Jose);
August 26: Gorge Amphitheatre in Quincy, WA.
Kings Of Leon band was formed in Nashville with a lot of Southern influences in the music. Eventually it became indie-darlings and won a number of Grammy awards. The group might be called as family act, as brothers Caleb, Jared and Nathan Followills hold down the vocals and rhythmic guitar, drums and bass respectively, and their cousin Matthew Followill plays the lead guitar. Kings Of Leon achieved initial success in the United Kingdom with 9 Top 40 singles, 2 BRIT Awards in 2008, and all 3 of the band's albums at the time peaked in the Top 5 of the UK Albums Chart. The band has achieved seven Grammy Award nominations, including three wins so far.
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Jay Moussa-Mann is the author of Edward's First Love and a short story author and screenwriter based in the North East of England. She has written and directed TV productions for a nonprofit organisation as well as several short films one of which won the Special Category Award at the International Sabaoth Film Festival. Her short story "Home Tomorrow" was published in the Home Tomorrow Anthology through 6e publishing. She has recently discovered a love for running, having spent her whole life being the 'non sporty one,' and enjoys a range of artistic outlets such as painting, art journaling and composing music.
Author Q & A
Can you tell us about the inspiration behind this story?
I had never realised how famous and how instrumental the Stockton to Darlington railway was in railway history. Since I live right next to Middlesbrough train station we often watch trains coming in and out. The topic caught me after watching a documentary about it and with further research I came across the fact that the railway pioneer Edward Pease, a key player in creating the Stockton to Darlinton railway, did not actually attend the opening celebrations due to the death of his son. It just got me thinking about how we create goals in our lives, living for them and making them so important and then in a moment, all our priorities can change.
When did you start writing?
I always naturally [have] been a creative writer. I was homeschooled until the age of 14 (when I went to boarding school) and English was always my favourite lesson, especially creative writing and poetry. I stopped for a long time during my teenage years and started more seriously again in my twenties.
Do you have a favourite genre?
I tend towards Sci-Fi and Fantasy but on the other end of the spectrum realistic stories really draw me in. I am currently enjoying "The Casual Vacancy" by JK Rowling. Brilliant characters!
What's your favourite book or short story?
I'm not sure if I have a favourite book. There are so many great ones out there it's hard to choose just one. I find myself going back to "The Magician's Nephew" by C S Lewis and "Rebecca" by Daphne de Maurier. I also love Daphne de Maurier's short stories.
What has been your biggest challenge as a writer?
Writing outside of my comfort zone and in a style I might not usually try. Once I made a habit of reading short stories, I began to branch out in the topics and styles in which I wrote in. "Edward's First Love" was an example of this. It was not a topic I would have naturally gone for and I really enjoyed the research side of it.
Are you currently working on a full-length novel and looking for a publisher?
I have very tentatively made a start on my first ever novel. It is a completely new medium for me as I have mostly written screenplays, short films and short stories. I find that the planning for a screenplay and a novel are fairly similar and the main important points like character development and plot points are the same.
What do you most enjoy about writing?
Writing allows me to say and think what I might not be able to say to friends and family. I am quite a quiet person who does not have a loud voice in a crowd so writing lets me speak out and be heard where I may not be in other situations. I relish exploring characters and seeing what they will do in certain situations. I know how dark and deadly we all can be and being able to use fiction to explore the depths of people is fascinating to me.
Amazon: Friend or foe?
You can visit her at www.jbmoussa.com and follow her on Twitter at @jbmoussa


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When Microsoft propelled Windows 10, it made its position on DirectX 12 clear: Windows 10 would be the main OS that bolstered the organization's most recent API, time frame. For quite a long time, the organization adhered to this position. At that point, recently, Microsoft reported that one game World of Warcraft would be permitted to exploit the DX12 API while running Windows 7. The purpose behind this stipend? Presumably China. The universe of Warcraft has consistently had an immense Chinese after, and Blizzard's choice to add DX12 backing to WoW was a critical advance for both the engineer and the API. Presently, Microsoft has reported that it's growing this program. In a short blog entry pointing a variety of API archives, Microsoft notes:
We have gotten a warm welcome from the gaming network, and we kept on working with a few game studios to further assess this work. To more readily bolster game designers at bigger scales, we are distributing the accompanying assets to enable game engineers to run their directx 12 download windows 10 games on Windows 7.The improvement direction report for how to move DX12 to Windows 7 really contains some valuable data on the fact that it is so hard to get games running under the more seasoned OS and what the distinctions are between the two. Microsoft states: We just ported the D3D12 runtime to Windows 7. In this manner, the distinction of Graphics Kernel found on Windows 7 still requires some game code changes, for the most part around the introduction code way, utilization of observed wall, and memory residency the board (which will all be nitty-gritty beneath). Early adopters announced from a couple of days to about fourteen days of work to have their D3D12 games going on Windows 7, however, the real designing work required for your game may change.
There are specialized contrasts between DX12 on Windows 7 and DX12 on Windows 10. DirectML (Direct Machine Learning) isn't bolstered under Windows 7, yet all different highlights executed in the October 2018 Windows 10 update are upheld. There are contrasts as far as API utilization (D3D12 on Windows 7 uses distinctive Present APIs), and some fence use examples are additionally unsupported.
There are, notwithstanding, a few points of confinement to help. Just 64-piece Windows 7 with SP1 introduced is bolstered. There's no PIX or D3D12 investigate layer on Windows 7, no mutual surfaces or cross-API interop, no SLI/LDA support, no D3D12 video, and no WARP support. As indicated by Microsoft, "HDR backing is symmetrical to D3D12 and requires DXGI/Kernel/DWM functionalities on Windows 10 yet not on Windows 7." This appears to suggest that HDR substance can work in Windows 7, yet it might be on the designer to actualize it appropriately.


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Beauty Studio Game: It is totally time for a fabulous makeover. Choose a friend, pick your favorite makeup, hair and jewelry, check out your style and new look. In this game, you have finally got the chance to run your very own beauty studio! Word has spread about your fast-acting choices, so choose the best look for your clientele! But first, make sure they like it! Check out all the options and style their hair, makeup and clothes in this cool skill game! So enjoy and have fun in playing this free online game on Round Games.
Also make sure to check out Beauty Princess Real Haircuts Game. You may enjoy playing it.


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It is the Year of the Lord not the Year of the Rooster or any other Chinese Astrological Zodiac Sign in the Chinese New Year! We are told to stay away from astrology in the Bible. All things belong to Christ including us. We were bought with a price, the precious blood of Jesus! We are to follow and honor Him and Him only. #YearoftheLord #Dog #YearoftheDog #ChineseNewYear
A Christian Blog about the Bible, Theology, God, Jesus Christ, Christian Music, Christian Movies, Family, Cats, Odd Holidays and much more.


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Three strains of a novel Bartonella species (Bartonella tamiae) were isolated from human patients from Thailand. Sequence analysis of six chromosomal regions (16S rRNA, gltA, groEL, ftsZ, rpoB, and the intergenic spacer region) and phenotypical analysis supported the similarity of the three strains and placed them within the genus Bartonella separately from previously described species.
Several species of the genus Bartonella cause numerous disorders, and most are thought to be zoonoses (1, 3). These Bartonella-associated illnesses occur worldwide, including in Asia, and they encompass a broad clinical spectrum, including fever, skin lesions, lymphadenopathy, endocarditis, and abnormalities of the central nervous system, liver, eye, and bone tissues (5). There has been a report indicating that humans are being exposed to Bartonella species in Thailand, though the investigators did not isolate the agents (7).
We report the characterization of three Bartonella strains isolated from blood samples of patients from Khon Kaen Province, Thailand, that belong to a novel Bartonella species. These strains were identified during the screening of blood clot specimens from a prospective study performed to determine the etiology of febrile illnesses in Thailand. It is the first report of culture-confirmed Bartonella infection in humans in Thailand.
Blood clots were separated from sera, stored at −70°C, and shipped to the U.S. CDC (Fort Collins, CO) for testing. Two approaches were used for the isolation of Bartonella from human clots: (i) blood clots were cocultivated with Vero E6 cells at 35°C with 5% carbon dioxide for 7 days and then subcultured onto rabbit blood-enriched agar and (ii) blood clots were inoculated into a preenrichment liquid, the Bartonella-Alphaproteobacteria growth medium (BAPGM) developed by Maggi et al. (6), and after 7 days of incubation at 35°C with 5% carbon dioxide were plated onto rabbit blood agar. The agar plates were incubated at 35°C with an aerobic atmosphere of 5% carbon dioxide for up to 30 days. The cultured bacteria were visualized with Gram stain by using standard light microscopy with an oil immersion objective at a magnification of 1,000×. For negative staining, a drop of suspension was placed on a copper grid coated with Formvar-carbon film and allowed to adhere for 10 min. The grids with adherent bacteria were stained by placing them on a drop of 2% potassium-phosphotungstic acid and air dried. The grids were examined with a Phillips 201 electron microscope. For ultrathin sectioning, the bacterial suspension was fixed in a mixture of 2.5% formaldehyde, 0.1% glutaraldehyde, 0.03% trinitrophenol, and 0.03% CaCl2 in 0.05 M cacodylate buffer (pH 7.2). Ultrathin sections were cut with a Leica-Reichert Ultracut S ultramicrotome, stained with 2% aqueous uranyl acetate and lead citrate, and examined with a Phillips 201 electron microscope.
The MicroScan rapid anaerobe identification panel (Dade Behring, Inc., West Sacramento, CA) was used to test the activities of preformed bacterial enzymes in accordance with the manufacturer's instructions on the preparation, incubation, and interpretation of the test results. For the study of antibiotic susceptibility, microbial suspensions were prepared according to a 0.5 McFarland standard from 5-day-old agar cultures and diluted 10-fold. Eight antibiotics (penicillin, cefotaxime, gentamicin, erythromycin, clindamycin, doxycycline, ciprofloxacin, and rifampin) diluted in Columbian agar supplemented with 5% sheep blood were tested. Results were read at the third and fifth days postinoculation.
Bacterial DNA was heat extracted at 95°C for 10 min from whole bacterial cells. Oligonucleotide primers were used for the amplification of single regions of the Bartonella citrate synthase (gltA), the cell division protein (ftsZ), the RNA polymerase beta-subunit (rpoB), the heat shock protein (groEL), and 16S rRNA genes, as well as the 16S-to-23S rRNA intergenic spacer (ITS) region. Positive and negative controls were included in each PCR to evaluate the presence of appropriately sized amplicons and possible contamination. Each PCR was conducted with a PTC-200 Peltier automated thermal cycler (MJ Research, Waltham, MA). PCR products were analyzed for the presence of amplicons of the correct size by electrophoresis of 5 μl of the product in 1.5% agarose gels containing ethidium bromide. Amplicons of the expected size were identified by size comparison to the positive control, and the resultant PCR products were purified using the QIAquick PCR purification kit (Qiagen, Germantown, MD) and sequenced in both directions using the same primers that were used for the PCR assay. Sequencing reactions were carried out with a PTC-200 Peltier thermal cycler, using the Quick Start dye terminator cycle sequencing kit (Beckman Coulter, Fullerton, CA).
Sequences were analyzed using Lasergene sequence analysis software (DNAStar, Madison, WI). The SeqMan program (DNAStar) was used to determine consensus sequences for the amplified region of the target genes, and the Clustal V program within Megalign (DNAStar) was used to align and compare homologous sequences. The sequences were then analyzed using PAUP 4.0 (Center for Biodiversity, Illinois Natural History Survey, Champaign, IL), and phylogenies were constructed using the maximum parsimony algorithm. To improve the statistical support of the phylogeny of the Bartonella genus, partial nucleotide sequences of six chromosomal regions (16S rRNA, 1,216 bp [final sequence length]; ftsZ, 788 bp; the ITS region, 1,076 bp; gltA, 323 bp; groEL, 825 bp; and rpoB, 1,209 bp) from 17 Bartonella strains were aligned and trimmed individually using MEGA version 3.1 and then concatenated in a multilocus sequence typing approach (Fig. 1). Multiple-sequence alignments were analyzed using the PAUP 4.0 software program, and phylogenies were constructed by using a distance-based likelihood method with the GTR+I+G DNA substitution model, as chosen by Modeltest v3.1. Trees were rooted using Afipia felis as the outgroup; because it was intended to be used solely for rooting the tree and not for phylogenetic comparison, only the 16S rRNA gene of A. felis was used. Missing sequences were treated as missing data.
Strain Th239 was isolated from a 38-year-old male patient who was admitted to the hospital with fatigue, myalgia, a headache, a maculopapular rash that had lasted for 22 days, and a fever that had lasted for 6 days. Strain Th239 was obtained by the cocultivation of blood with Vero E6 cells. After 7 days, the suspension was found to be positive by PCR amplification of a Bartonella-specific fragment of the gltA gene. Subsequently, the inoculated Vero E6 cells were subcultured on rabbit blood agar, and very small colonies appeared on the agar 17 days postinoculation. The growth rate increased after several sequential subculturing passages of the collected bacterial suspension. After each passage, the suspensions of the Vero E6 cells were PCR positive for amplification of the targeted piece of the gltA gene.
Strain Th307 was obtained from a 41-year-old female admitted to the hospital with an initial diagnosis of a pterygium in each eye. The strain was isolated after the inoculation of the patient's blood clot into preenrichment BAPGM. After a 7-day incubation, the suspension was found to be positive for Bartonella organisms by PCR using the gltA gene as a target. The inoculated medium was then placed on rabbit blood agar and incubated at 35°C with 5% CO2. Bartonella-like colonies were observed after 5 days of cultivation and confirmed to be positive by PCR.
Strain Th339 was obtained from a 12-year-old male patient admitted to the hospital with fever, fatigue, myalgia, a headache, and a petechial rash on his arms and legs that had lasted for 2 days. The strain was isolated after the inoculation of the patient's blood clot into preenrichment BAPGM and a 10-day incubation. Inoculated medium was then placed on rabbit blood agar and incubated at 35°C with 5% CO2. Bartonella-like colonies were observed on the agar plate after an additional 12 days.
BLAST searches indicated that all sequences of the 16S rRNA, gltA, groEL, ftsZ, rpoB, and the ITS region of strains Th239, Th307, and Th339 are closely related to the homologous sequences of various Bartonella species and unnamed Bartonella strains. Phylogenetic analyses based on the parsimony method (heuristic search), neighbor joining, and MegAlign alignments of all sequences (16S rRNA, gltA, groEL, ftsZ, rpoB, and the ITS region) supported the novelty of the new isolate and suggested a distant phylogenetic lineage in the genus Bartonella. Phylogenetic analysis of a concatenated, multiple-sequence alignment of the 16S rRNA, gltA, ftsZ, groEL, rpoB, and ITS region nucleotide sequences using a distance-based maximum likelihood algorithm supported the placement of the new isolates within a distinct phylogenetic lineage of the Bartonella genus (Fig. 1).
The structures of phylogenetic trees and the percentages of divergence between the sequences of the 16S ribosomal genes of strains Th239, Th307, and Th339 and sequences in the GenBank nucleic acid database demonstrated that these strains were close to representatives of the genus Bartonella. The genetic distances between the isolates and representatives of the genus Brucella, which is the taxonomic group closest to Bartonella, were evidently greater than the distances between these isolates and other Bartonella species. The 16S rRNA gene sequence analysis indicated that these three strains represent a distant phylogenetic lineage in the genus Bartonella. The 16S rRNA sequences of strains Th239, Th307, and Th339 exhibited the closest phylogenetic relationship with three sequences of three uncultured Bartonella species clones (pAJ203 [AY370185], pAJ208 [AY370186], and pAJ210 [AY370187]) obtained from the honeybee Apis mellifera (4).
Because of the genetic similarity among the strains, only one strain, Th239, was used for further phenotypical characterization. Gram staining of isolate Th239 revealed rod-shaped, gram-negative bacilli that were small, straight, and slightly curved. Transmission electron microscopy of negatively stained bacteria showed small, rounded rods ranging from 0.7 to 1.2 μm in length and 0.5 to 0.6 μm in width. Some bacteria had bundles of fibrils approximately 15 nm thick and 30 nm in length with a periodicity ranging from 30 to 120 nm and with polar distribution (Fig. 2A). Examination of ultrathin sections revealed typical gram-negative morphology with a wavy cell wall. The bacteria appeared to be approximately 0.3 μm by 0.8 μm (Fig. 2B). Therefore, the sizes of the organisms, taking into account measurements from both ultrathin sections and negative staining, appear to range from 0.3 to 0.6 μm in width and from 0.7 to 1.2 μm in length.
Most of the biochemical properties of strain Th239 were typical for bacteria of the Bartonella genus. Specifically, enzymatic hydrolysis results were negative for p-nitrophenyl-beta-d-galactopyranoside, p-nitrophenyl-alpha-d-galactopyranoside, p-nitrophenyl- N-acetyl-beta-d-glucosaminide, p-nitrophenyl-alpha-d-glucopyranoside, o-nitrophenyl-beta-d-glucopyranoside, p-nitrophenyl-alpha-l-fucopyranoside, p-nitrophenyl-alpha-d-mannopyranoside, l-proline-beta-naphthylamide, l-pyrrolidonyl-beta-naphthylamide, trehalose, urea, indole, and nitrate. Positive reactions were observed in the enzymatic hydrolysis of bis-p-nitrophenyl-phosphate, p-nitrophenyl-phosphate, l-leucine-beta-naphthylamide, l-lysine-beta-naphthylamide (acid and alkaline), dl-methionine-beta-naphthylamide, glycylglycine-beta-naphthylamide, glycine-beta-naphthylamide, l-arginine-beta-naphthylamide, l-tryptophane-beta-naphthylamide, and 3-indoxyl-phosphate. The unique property of strain Th239 in contrast to other Bartonella strains was its 3-indoxylphosphate activity.
The following MICs of antibiotics were observed with strain Th239: penicillin, 4 μg/ml; cefotaxime, >4 μg/ml; gentamicin, 0.5 μg/ml; erythromycin, >4 μg/ml; clindamycin, 32 μg/ml; doxycycline, 4 μg/ml; ciprofloxacin, 8 μg/ml; and rifampin, 4 μg/ml.
Our findings support the possibility of Bartonella strains being causes of human disease in Thailand. Two of the three patients were febrile, and all three had clinical and laboratory findings similar to those found for patients infected with other forms of bartonellosis (5). Mild anemia observed in all patients is presumed to have resulted from the infection of red blood cells, and headache, myalgia, and abnormalities in liver function, consistent features in these three patients, are commonly identified in other Bartonella infections.
All three patients reported trapping or killing rats in their houses, and two of them reported recent rat exposures within the 2 weeks prior to the onset of illness. Further investigation is needed to determine the animal reservoir and any possible vectors for B. tamiae. Previous investigations of rodents of northern Thailand demonstrated that 9% of the tested animals were Bartonella culture positive (2), and phylogenetic analysis indicated a high diversity of the Bartonella strains obtained from Thai rodents. Also, Bartonella species have been identified in cats and fleas from Thailand (8, 9). However, to date, no homologous mammalian or flea Bartonella sequences phylogenetically similar to B. tamiae have been identified.
Based on a combination of genetic and phenotypic characteristics, we consider these described strains to be representatives of a novel Bartonella species. Bartonella tamiae (tam.i′ae. N.L. fem. gen. n. tamiae, of Tami) is the name proposed to honor the late Tamara (Tami) Fisk, who organized the febrile illness study in Thailand from which this bacterial species originated. The prototype strain (Th239) isolated from the blood of a Thai patient has been deposited in the American Type Culture Collection (ATCC BAA-1343), the National Collection of Type Cultures (United Kingdom, NCTC 13398), and the Japan Collection of Microorganisms (JCM 14580).
Nucleotide sequence accession numbers.
Sixteen unique nucleotide sequences were identified among the obtained three isolates. The three gltA sequences were assigned the GenBank accession numbers DQ395177 (strain TH239), EF605279 (strain TH307), and EF605280 (strain TH339). The ftsZ sequences were assigned the accession numbers DQ395178 (TH239), EF605281 (TH307), and EF605282 (TH339). The 16S-to-23S ribosomal ITS region sequences were assigned the accession numbers DQ395180 (TH239), EF605283 (TH307), and EF605284 (TH339). The groEL sequence was assigned the GenBank accession number DQ395179 (TH239). The rpoB sequences were assigned the accession numbers EF091855 (TH239), EF605285 (TH307), and EF672730 (TH339). The novel 16S ribosomal gene sequences were assigned the accession numbers DQ395176 (TH239), EF672728 (TH307), and EF672729 (TH339).
This project was supported by the International Emerging Infections Program and the Global Disease Detection Network of the U.S. Centers for Disease Control and Prevention.
For their support and collaboration, we are indebted to Khanchit Limpakarnjanarat of the IEIP; Akradeth Pensiri, Chawalit Nilvarangkul, Kamol Srilom, and Somjit Dechasatien of the Kohn Kaen Provincial Health Office; Kasem Pataralitikun and the staff at Nong Song Hong Hospital; and Aumporn Ratanaparinya and the staff at Kranuan Crown Prince Hospital.
- Received 2 November 2007.
- Accepted 3 December 2007.
- Copyright © 2008 American Society for Microbiology