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Down syndrome
- a genetic disorder, associated with the presence of an extra chromosome 21, characterized by mild to severe mental retardation, weak muscle tone, a low nasal bridge, and epicanthic folds at the eyelids.Also, Down's syndrome. Formerly, mongolism. Also called trisomy 21.[1960-65; after John L. H. Down (1828-96), British physician]
* * *or trisomy 21Congenital disorder caused by an extra chromosome (trisomy) on the chromosome 21 pair.Those with the syndrome may have broad, flat faces; up-slanted eyes, sometimes with epicanthal folds (whence its former name, mongolism); mental retardation (usually moderate); heart or kidney malformations; and abnormal fingerprint patterns. Many persons with Down syndrome can live and work independently or in a sheltered environment, but they age prematurely and have a short (55-year) life expectancy. The risk of bearing a child with the disorder increases with the mother's age; it can be detected in the fetus by amniocentesis.
* * *also called Down's syndrome, trisomy 21, or (formerly) Mongolismcongenital disorder caused by an extra chromosome (chromosome number) on the chromosome 21 pair, giving the person a total of 47 chromosomes rather than the normal 46. British physician John Langdon Down first described the physical features of the disorder in 1866, and thus the disorder was later named for him. The physical and mental impacts of Down syndrome range from mild to severe. Some common physical signs of the disorder include a small head, flattened face, short neck, up-slanted eyes, low-set ears, enlarged tongue and lips, and sloping underchin. Other characteristics of the disorder may include poor muscle tone, heart or kidney malformations (or both), and abnormal dermal ridge patterns on the palms of the hands and soles of the feet. Intellectual disability occurs in all persons with Down syndrome and usually ranges from mild to moderate. congenital heart disease is found in about 40 percent of people with Down syndrome.There are three forms of Down syndrome. The most common form is trisomy 21, in which all of an individual's cells contain three, as opposed to two, copies of chromosome 21. The extra chromosome, identified in 1959 by French geneticist Jérôme-Jean-Louis-Marie Lejeune, is a result of random, abnormal events in cell division that occur during embryonic development or during the development of egg or sperm cells. The presence of the extra chromosome in cells gives rise to the signs and symptoms of Down syndrome. In mosaic Down syndrome, a rare form of the disorder, only some of an individual's cells contain a third copy of the chromosome. Because there are some cells that retain the normal 46 chromosomes, certain aspects of the disorder, such as intellectual disability, are not as severe in people with mosaic Down syndrome relative to people with trisomy 21. The third form, translocation Down syndrome, occurs when the extra chromosome in the 21 pair breaks off and attaches itself to another chromosome. Translocation Down syndrome is the only form that may be inherited. A parent who possesses a balanced translocation—a chromosome rearrangement with no extra genetic material from chromosome 21—can pass the translocation to an offspring. Carriers of balanced translocations do not have signs or symptoms of the disorder. Mothers carrying a translocation have a 12 percent risk of transmitting the genetic rearrangement to their offspring, whereas fathers carrying a translocation have a 3 percent risk of transmission.Down syndrome occurs in about 1 in every 740 live births. The incidence of the disorder increases markedly in the offspring of women over the age of 35. For example, the incidence of the disorder in the offspring of young women is only about 1 in 1,000, whereas its incidence in the offspring of women over age 40 can range from about 1 in 100 to 1 in 30. In addition, women who have had one child with Down syndrome have a 1 percent chance of having a second child with the disorder. Screening tests using both ultrasound and blood analysis that are performed between the 11th and 14th week of pregnancy can detect most incidences of Down syndrome. In cases where Down syndrome is suspected, the disorder can be confirmed using amniocentesis or chorionic villus sampling. In these diagnostic tests, samples of fetal cells are taken from the amniotic fluid or from the mother's placenta and analyzed for the presence of the abnormal chromosome.With modern medical care, many persons with Down syndrome live into adulthood, although they do have a shorter life expectancy (55) than normal adults, because they develop the degenerative conditions of old age prematurely. Complications associated with Down syndrome include major heart defects that cannot be corrected by surgery, infection such as pneumonia, and leukemia. Depending on the severity of intellectual disability, some people with Down syndrome never become self-supporting. However, the majority can be taught to contribute usefully in the home or in a sheltered working or living environment after they are grown. There are no drugs designed to treat Down syndrome because little is known about the exact molecular mechanisms that give rise to the symptoms of the disorder. However, scientists have identified a gene on chromosome 21 that disrupts normal embryonic cell development in trisomy 21 and may cause the manifestation of certain symptoms. As a result, this gene is a potential target for the generation of therapeutic agents capable of alleviating symptoms of Down syndrome.
* * *
Universalium. 2010.
Look at other dictionaries:
Down syndrome — Down syn drome, Down s syndrome Down s syn drome, n. (Med.) A congenital disorder caused by an extra chromosome 21 in some or all cells. It causes a variable number and degree of abnormalities, including retarded growth, mental retardation, a… … The Collaborative International Dictionary of English
Down syndrome — [doun] n. [after J. L. H. Down (1828 96), Brit physician] a congenital condition characterized by abnormal chromosomes, mental deficiency, a broad face, slanting eyes, a short fifth finger, etc.; Mongolism: also called Down s syndrome … English World dictionary
Down syndrome — Down syndrome. См. болезнь Дауна. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) … Молекулярная биология и генетика. Толковый словарь.
Down syndrome — Down ,syndrome noun uncount a medical condition that someone is born with, that makes them develop mentally and physically in a different way from most people … Usage of the words and phrases in modern English
Down syndrome — Classification and external resources Boy with Down syndrome assembling a … Wikipedia
Down syndrome — A common chromosome disorder due to an extra chromosome number 21 (trisomy 21). Down syndrome causes mental retardation, a characteristic face, and multiple malformations. Down syndrome is a relatively common birth defect. The chromosome… … Medical dictionary
Down syndrome — noun a congenital disorder caused by having an extra 21st chromosome; results in a flat face and short stature and mental retardation • Syn: ↑mongolism, ↑mongolianism, ↑Down s syndrome, ↑trisomy 21 • Hypernyms: ↑trisomy, ↑birth defect, ↑ … Useful english dictionary
Down syndrome — Down′ or Down s syndrome n. pat a genetic disorder associated with the presence of an extra chromosome 21, characterized by mental retardation, weak muscle tone, and epicanthic folds at the eyelids Formerly, mongolism Also called trisomy 21… … From formal English to slang
Down syndrome — Down s syndrome … The new mediacal dictionary
Down syndrome — /ˈdaʊn sɪndroʊm / (say down sindrohm) noun a genetic condition resulting from a third chromosome on the 21st chromosomal pairing, characterised by varying degrees of intellectual and physical impairment. Also, Down s syndrome. {from John Langdon… … Australian English dictionary


text: Filmmaker Lounge Kingdomwood International Film Festival Filmmaker Lounge Location: Lower Level Classroom Event details:Start dateOctober 4, 2019 8:00 amEnd dateOctober 4, 2019 6:00 pmCalendarKingdomwood International Film FestivalGoogle Calendar iCal feed URL https://kingdomwood.com/?rhc_action=get_icalendar_events&ID=887 Get Feed for iCal (Google Calendar). This is for subscribing to the events in the Calendar. Add this URL to either iCal (Mac) or Google Calendar, or any other calendar that supports iCal Feed. Download ICS file Organizer details:OrganizerVenue DetailsVenueLower Level ClassroomInformation

subset: commoncrawl


text:
I've been using Shipito for quite a while to order from sites that don't ship internationally but I've tried a couple recently that reject my order because my Visa billing address doesn't match the address I am trying to ship to (Shipito address).
I remember someone telling me a while back they had signed up for an online credit card with a US address (they were using it to buy tracks on an imported version of Rock Band 2 I think- or something similar that required a card with a US address) that you can credit funds to using your existing NZ card but can't remember the site. Anyone know of something like this?


text:
Watersmeet gained a much deserved success when making it third time lucky in the Betway All-Weather Marathon Championships Conditions Stakes at Lingfield.
Having finished second in 2017 and third 12 months ago, the Mark Johnston-trained eight-year-old finally hit the jackpot in the two-mile prize.
Despite missing the break, the son of Dansili, who usually front-runs, came with a strong challenge from off the pace before being kicked on by Joe Fanning around a furlong from home to cross the line two and a quarter lengths clear off odds-on favourite Amade.
Johnston said of the 7-1 winner: "I've often thought he has deserved a big one on the turf or all-weather. He has actually run three times before in these finals, as he ran in the mile-and-a-quarter race and has been twice placed in this race, so it was his turn.
"He took the blind off too early, hit the gates and sat back on his hocks and missed it, so he was back in the field and Joe said he had to think again.
"He got lucky when the favourite went round the outside, so he thought he would follow that. Joe didn't know himself how far he won by.
"I didn't think his chance had gone, but I hate seeing them go wide round the bend, although at the same time I wanted Joe to get up there a bit more. All's well that ends well."
Looking to future engagements, Johnston pointed towards another tilt at the Northumberland Plate at Newcastle in June for the winner, a race in which he finished fourth in last year.
He said: "I don't know how many times he has run in the Northumberland Plate before, but he should be well capable of winning a race like that.
"Those races have got to be for him as he is eight years old and there is nothing else for him."
Ryan Moore rode the perfect race from the front in making all aboard Heavenly Holly in the Ladbrokes All-Weather Fillies' And Mares' Championships Conditions Stakes.
Although faced with the widest draw in stall 12, the three-times champion jockey quickly got the Hugo Palmer-trained four-year-old over to the inside to take up pole position in the seven-furlong event.
Moore stole a few more lengths rounding the home turn with an injection of pace on the 9-1 chance, before holding the fast-finishing Island Of Life at bay by a length.
Palmer said: "She got beat over seven and a half furlongs last time in a Listed race and she might have got beaten three-quarters of a length today if it had been another half a furlong.
"The obvious target is to come back here on Derby trials weekend for the Chartwell. This is a real testament to patient owners. So many people push trainers to run horses before they are ready, and these guys have been so unbelievably patient.
"They have been so patient and have now been rewarded, which is fantastic."
Christophe Soumillon showed why he is one of the best in the business when keeping a calm head to galvanise Pizzicato to glory in the Ladbrokes 3 Year Old All-Weather Championships Conditions Stakes.
Arriving with a what appeared a double handful late on in the six-furlong contest, the multiple Group One-winning rider had to nurse the Fabrice Chappet-trained 11-4 winner home to better the hat-trick-seeking Deputise by a short head.
Soumillon said: "Unfortunately when you ask him to go he is able to stop when he hits the front and that is what he did. I was quite lucky to let him hang in and come close to the horse that finished second and that helped him concentrate to the line.
"Unfortunately his first few strides didn't go well compared with his last few races. I was hoping to ride him a bit closer. With that jump I had to ride him a bit further back.
"I was quite happy as the two good horses in the race were just in front of me and I knew one of them would bring me back in the straight, so I was quite confident."


text:
Ade Adesomoju, Abuja
A governorship aspirant in Osun State on the platform of the All Progressives Congress, Mr Kunle Adegoke, has filed a suit before the Federal High Court in Abuja challenging the party's primary held on July 20.
He wants the court to stop the Independent National Electoral Commission from recognising the outcome of the exercise.
Mr Gboyega Oyetola, the Chief of Staff to the outgoing Governor of Osun State, Mr Rauf Aregbesola, had emerged from the election as the party's candidate ahead of the September 22 governorship election in the state.
The party had declared Oyetola as the winner of the primary in which 16 other aspirants, including Adegoke, participated.
But Adegoke, a lawyer, contended in his suit marked FHC/ABJ/CS/804/2018, which he filed on Friday, that the conduct of the party's primary violated the Nigerian constitution, the Electoral Act, 2010 as well as the relevant provisions of the APC constitution and the Regulation for the Conduct of Political Party Primaries of the Independent National Electoral Commission.
The suit filed on his behalf by his lawyer, Mr Ayotunde Ogunleye, had the APC and INEC as the two defendants.
In an affidavit filed in support of his originating summons, the plaintiff alleged that the "direct method" adopted by the party allowing all general members of the party to vote in the primary "was a departure from the extant 2014 guidelines of the party."
He noted that he had also, in an open letter, challenged the National Chairman of the party, Mr Adams Oshiomhole, informing him that there was no membership register of the party by which the party could conduct a credible direct primary.
Adegoke also said he informed Oshiomhole that the adoption of direct primary without the membership register would be in flagrant violation of the constitution of the party due to the time of its adoption vis-à-vis the general requirements of the law.
He said the APC failed to notify him as an aspirant or INEC in writing not later than 21 days to the date of the primary, the details including the specific venue, date and time for the conduct of its nomination of the candidate before holding same on July 20, 2018.
He sought an order of the court "nullifying" the primary for allegedly violating the Nigerian Constitution, the Electoral Act, and the other cited laws, rules and regulations of the party and INEC.
He asked the court to make an order restraining INEC "from according any recognition to the outcome of the said Osun State governorship primary of the 1st defendant held on the 20th day of July, 2018 in Osun State…"
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All rights reserved. This material, and other digital content on this website, may not be reproduced, published, broadcast, rewritten or redistributed in whole or in part without prior express written permission from PUNCH.
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text:
Job Opportunity in Lebanon
– Promotion & Packaging Officer
Location: Lebanon
-Male, Presentable
-Bachelor Degree in Marketing or similar field.
-2-3 years Experience in packaging, labeling, promotion campaigns….
To apply, please send your CV to: firstname.lastname@example.com– kindly mention the position title in the subject mail.
Do not hesitate to follow our website and Christiane Mouawad on Linkedin for more information
Kindly like and share our social platform
and stay updated with our daily news & monthly offers!
Facebook | instagram | pinterest | Twitter | linkedin | Behance | Offers
click here to get a 20% on Designduedate Certified international driving license
Job Opportunity in Lebanon
Job Opportunity in Lebanon


text:
- Note: Data for some countries are based on fiscal years. 1Movements in consumer prices are shown as annual averages. 2Percent of GDP. 3Percent. 4Includes Bahrain, Libya, Oman, and Yemen. 5Includes Djibouti and Mauritania. Excludes Syria because of the uncertain political situation.
The International Monetary Fund has revised its 2015 economic growth projection downward for the Middle East and North Africa by a greater margin than any other country or region in the world in its latest economic outlook, reflecting expectations of a fragile global recovery and ongoing regional political instability.
The IMF on Tuesday lowered its projections for global growth this year and next year, painting a picture of a slower-than-anticipated recovery in advanced economies coupled with emerging markets that are expected to struggle because of lackluster demand and lower world trade growth.
Globally, the IMF said growth this year will be 3.3%, a downward revision from a July estimate of 3.4%.
In the Middle East and North Africa, where conflict and political instability have raged in Iraq, Syria, Libya and Yemen this year, the IMF is forecasting 2.6% growth in 2014 followed by 3.8% growth next year. The 2015 growth figure is a full percentage point lower than the IMF's estimate in July, the largest downward revision of any region or country it examined in its world economic outlook.
The challenges in the Middle East aren't uniform. In the Gulf Arab oil-exporting countries, growth is expected to be steady, helped by a modest increase in oil production and a much bigger contribution from the non-oil sector.
The story is different in places where political upheaval and violence have been most acute. In Iraq, where Islamic State militants have taken large swaths of territory since the summer, the IMF expects GDP to decline by 2.7% this year. The IMF didn't even measure Syrian GDP, citing the unstable political situation there more than three years into a civil war.
The IMF's prescriptions for Middle East growth are familiar ones. For oil exporters, the IMF recommends fiscal consolidation to help rein in budget deficits that ballooned after the financial crisis and Arab Spring unrest. Oil-rich countries have used their deep pockets to bolster social infrastructure – schools, hospitals, homes for nationals and other projects – but economists warn that the pace of spending growth isn't sustainable in the long run.
For oil importers, major structural reforms are still necessary in many countries to keep them competitive and solve rampant unemployment, the IMF said.
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(via WSJ Blogs)


text:
Jim Gray went too far in his Pete Rose interview
But the controversy has been blown out of proportion, says Bruce Fretts
Jim Gray went too far in his Pete Rose interview
Earlier this week, my EW colleague Ken Tucker posed the question, "Who needs the World Series, anyway?" With all due respect, I do — I'm a baseball fanatic. What I don't need is the continuing controversy over Jim Gray's alleged "ambush" interview with Pete Rose.
Yes, Gray blew it by raining on Rose's parade. The Cincinnati Reds slugger was basking in the honor of having been selected by the fans as part of the All-Century Team when the NBC reporter started grilling him about the gambling allegations that led to his being banned from the game (and the Hall of Fame). Instead of dropping the subject when it became clear Rose wasn't going to give up the goods, Gray kept pummeling away. He was straining to get a scoop, and he wound up looking like a fool.
Outraged viewers deluged NBC and sports-radio stations around the nation with calls of protest over Gray's actions. He probably didn't help the situation by issuing a half-hearted statement of remorse (any apology that includes the word "if" is no apology at all). Then after Tuesday night's victory, New York Yankee hero Chad Curtis embarrassed Gray on-camera by refusing to answer his questions and storming off the field.
Was this petulant display really necessary? (And before you accuse me of Yankee-bashing, let me disclose that although I would've pulled for the Mets in a subway series, I root for both of New York's baseball teams.) All Gray did was commit an error — something that baseball players do on the field all the time, and reporters don't boycott them as a result.
It'd be a shame if this media brouhaha overshadowed what really matters about the World Series: the games. Just because Rose wasn't allowed to enjoy a moment of glory doesn't mean the triumphs of Derek Jeter and the other future Hall of Famers out on the field should be tarnished by a silly "scandal." I bet even Pete Rose would agree.


text:
Force C++ language version? Follow
We are try to using Visual Studio 2017 with ReSharper++ and VisualGDB for developing embedded application.
But RS++ not resolve current C++ version (C++17).
Is possible to force language version for project?
At the moment working with RC++ is very dificult.
Andrzej Tatar
Hello Andrzej,
At the moment R++ reads language version only from project settings. The feature request to implement a dedicated setting is https://youtrack.jetbrains.com/issue/RSCPP-22285.
In your case you need to instruct VisualGDB to pass the "/std:c++17" command-line argument to IntelliSense. R++ will then pick it up and enable C++17 support.
It seems to me that RS++ resolved the correct C++ version.
My changes:
- added line in VS project : <LanguageStandard>stdcpplatest</LanguageStandard>
- forced included file that contains:
#ifdef __cplusplus
#undef __cplusplus
#define __cplusplus 201704U
You are right, it looks like the value of __cplusplus is not defined according to the language standard with non-MSVC toolsets. I'll fix this in 2018.3 so the #ifdef is not necessary - https://youtrack.jetbrains.com/issue/RSCPP-24361.
Note that you can also use the __RESHARPER__ macro to add defines just for R++, so something like this should also work:
#ifdef __RESHARPER__
#define __cplusplus 201704U
The __cplusplus define should no longer be necessary in EAP 7 (https://www.jetbrains.com/resharper/eap/), the language standard option should be enough. Please let me know if you still experience the issue.
It seems to me that works good, but I had to turn off Visual Studio IntelliSense manually because red underscores (errors) were visible.
Now everything looks great.
Please sign in to leave a comment.


text:
P-2 and P-3 Visas For Artists and Entertainers
What is a P-2 visa?
The P-2 nonimmigrant category is reserved for those who are coming to the US through an exchange program in which US based and a foreign-based organizations exchange artists and entertainers. The visas are available to both individuals and groups. There are few requirements for these exchange programs so long as the people involved are of equal caliber, will be employed in similar conditions and for similar periods of time, and there are similar numbers of people being exchanged. The P-2 category also includes support personnel.
What documents should I include in my P-2 application?
Among the specific documents required in the P-2 application are the following:
- A copy of the agreement between the US and foreign organizations about the exchange program,
- A letter from the US organization describing the exchange program,
- Evidence that a US labor union or similar organization was involved in negotiating the exchange, and
- Evidence that the foreign artists and entertainers in the US will be employed in conditions similar to those under which US artists and entertainers will be employed abroad.
Is there anything I should do before applying for a P-2 visa?
If you are considering applying for a P-2 visa, check with the organization that represents artists in your field. For example, the American Federation of Musicians has a P-2 program allowing for the exchange of American and Canadian musicians.
What is a P-3 visa?
P-3 visas are granted to artists and entertainers who come to the US to participate in a "program that is culturally unique." The statute does not make clear whether the performance that will be given must be culturally unique, or whether the performance must also be given in a setting that is culturally unique. While the USCIS initially took the position that the program must be culturally unique, it has since relaxed the standards to allow issuance of P-3 visas so long as the performance that will be given is culturally unique. P-3 essential support personnel are also given P-3 visas.
What documents should I include in my P-3 application?
The following evidence must be submitted with a P-3 application:
- Affidavits or letters from experts regarding the authentic cultural uniqueness of the performance, or
- Other documentation that the performance is culturally unique, such as material published in newspapers and trade journals, and
- Evidence that each performance will be culturally unique.
The application must include an I-129 Form as well as a P Supplement and the 0. It must be submitted to the USCIS Service Center having jurisdiction over the petitioner's location.


text:
10 Meith 2019, 14.43
Tomorrow, Tuesday at 1.30pm, the Committee on Budgetary Oversight will commence the first of two sessions, with the latest Fiscal Assessment Report to be discussed.
Representatives from the Irish Fiscal Advisory Council are due before the committee at 1.30pm to discuss the Fiscal Assessment Report.
Separately, the Minister for Finance and Public Expenditure and Reform, Paschal Donohoe TD appears at 3.30.
Minister Donohoe TD will assist the committee in its consideration of the Review of Local Property Tax: the report of the Inter-Departmental Group - March 2019.
"The very latest Irish Fiscal Advisory Council report merits detailed consideration, as the issues raised throughout have the potential to impact upon the lives of all of us" said Committee Chairman Colm Brophy TD.
The mandate of the Irish Fiscal Advisory Council is to endorse, as it considers appropriate, the macroeconomic forecasts prepared by the Department of Finance on which the Budget and Stability Programme Update are based; assess the official forecasts produced by the Department of Finance; assess government compliance with the Budgetary Rule; assess whether the fiscal stance of the Government in each Budget and Stability Programme Update (SPU) is conducive to prudent economic and budgetary management.
Mr. Brophy added: "This report was just finalised on Friday last, June 7, so we welcome the opportunity to have such an early opportunity to engage with the Council in relation to issues such as Sustainable Growth, Corporation Tax Receipts, Tax Forecasts and Capital Projects. Furthermore, as Brexit nears, we welcome the opportunity to explore the Fiscal Impacts of Hard Brexit Scenarios set out in the report."
"Separately, the Committee looks forward to meeting with the Minister for Finance and Public Expenditure and Reform to carry out scrutiny of the Review of Local Property Tax."
The meeting in Committee Room 4 can be viewed live here
Learn about the Committee's recent reports, statements and membership here
Media enquiries
Alan Neary,
Tithe an Oireachtais,
Oifigeach Cumarsáide,
Teach Laighean,
Baile Átha Cliath 2
+353 1 618 4743
+353 86 010 7500
Twitter: @OireachtasNews
Committee membership
Fine Gael
Solidarity - People Before Profit
Fianna Fáil
Fine Gael
Independents 4 Change
Labour Party
Fianna Fáil
Fianna Fáil
Sinn Féin
Fine Gael
Fianna Fáil
Fianna Fáil
Sinn Féin
Green Party


text:
Back to Journals » Clinical Epidemiology » Volume 10
Guidance for using pilot studies to inform the design of intervention trials with continuous outcomes
Authors Bell ML, Whitehead AL, Julious SA
Received 14 July 2017
Accepted for publication 14 November 2017
Published 18 January 2018 Volume 2018:10 Pages 153—157
DOI https://doi.org/10.2147/CLEP.S146397
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Professor Henrik Toft Sørensen
Melanie L Bell,1 Amy L Whitehead,2 Steven A Julious2
1Department of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ, USA; 2Medical Statistics Group, Design, Trials and Statistics, School of Health and Related Research (ScHARR), University of Sheffield, Sheffield, UK
Background: A pilot study can be an important step in the assessment of an intervention by providing information to design the future definitive trial. Pilot studies can be used to estimate the recruitment and retention rates and population variance and to provide preliminary evidence of efficacy potential. However, estimation is poor because pilot studies are small, so sensitivity analyses for the main trial's sample size calculations should be undertaken.
Methods: We demonstrate how to carry out easy-to-perform sensitivity analysis for designing trials based on pilot data using an example. Furthermore, we introduce rules of thumb for the size of the pilot study so that the overall sample size, for both pilot and main trials, is minimized.
Results: The example illustrates how sample size estimates for the main trial can alter dramatically by plausibly varying assumptions. Required sample size for 90% power varied from 392 to 692 depending on assumptions. Some scenarios were not feasible based on the pilot study recruitment and retention rates.
Conclusion: Pilot studies can be used to help design the main trial, but caution should be exercised. We recommend the use of sensitivity analyses to assess the robustness of the design assumptions for a main trial.
Keywords: pilot, feasibility, sample size, power, randomized controlled trial, sensitivity analysis
This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License. By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.Download Article [PDF] View Full Text [HTML][Machine readable]


text: Sections View Full Chapter Figures Tables Videos Full Chapter Figures Tables Videos Supplementary Content ++ INTRODUCTION ++ At this point, it's time to consider the diagnostic interview. By now you know the major mental disorders you will need to master in medical settings—depression, anxiety, and prescription and other substance misuse. In the interview, you're looking for criteria that distinguish among these disorders and their subsets. The interview format we now present describes the categories of data needed and how it can be written up for your records. ++ You learned in Chapter 3 to begin all interviews with the patient-centered interview.1 To briefly review, one begins any interaction by ensuring the patient's comfort (step 1) and setting an agenda for the visit (step 2). You then proceed to the true patient-centered part of the interaction (steps 3 and 4) to determine open-endedly the patient's physical symptom and personal story. You next elicit any emotion associated with these stories and empathically respond by Naming it, expressing Understanding of it, Respecting it, and offering Support (NURS). See Table 3-1 in Chapter 3. ++ Following this 3- to 5-minute patient-centered introduction, you transition to develop the details of the chief concern you elicited during agenda setting (step 2). Even in patients with a mental disorder, this step will often involve physical symptoms, and you need to pin down these details as you normally would via the history of present illness (HPI), past medical history (PMH), social history (SH), family history (FH), and review of systems (ROS). For mental disorders, the format is essentially the same. ++ You may have already uncovered psychological symptoms (of a mental disorder) in your patient-centered interviewing. As you expand the patient's physical and personal stories, you will often identify them. Once you have identified these symptoms, you proceed to the clinician-centered part of the interaction to pin down crucial diagnostic details, as outlined in Chapters 4, 5, 6. On the other hand, recall that you may not have gotten many psychological symptoms in the patient-centered component, and that you will need to actively inquire about them during clinician-centered inquiry. ++ So how might you elicit the psychological symptoms? What are some questions you can use to screen for a mental disorder during clinician-centered interviewing? Table 7-1 presents the disorders discussed in Chapters 4, 5, 6; your clinician-centered questions will focus on differentiating among them. Table 7-2 suggests some specific screening questions for depression, mania/hypomania, and drug/alcohol abuse. Now, you generally do not ask all the questions in Table 7-2 in screening; rather, you should focus on the areas where you have suspicions. These concerns will commonly include depression and/or anxiety because the 2 are the most common disorders and often occur together. When answers to screening questions are positive, you conduct your subsequent history to elicit the differentiating material described in Chapters 4, 5, 6. Tables 7-3 and 7-4 list some less ... GET ACCESS TO THIS RESOURCE Sign In Username Error: Please enter User Name Password Error: Please enter Password Forgot Username? Forgot Password? Sign in via OpenAthens Sign in via Shibboleth Get Free Access Through Your Institution Contact your institution's library to ask if they subscribe to McGraw-Hill Medical Products. Access My Subscription GET ACCESS TO THIS RESOURCE Subscription Options Pay Per View Timed Access to all of AccessMedicine 24 Hour $34.95 (USD) Buy Now 48 Hour $54.95 (USD) Buy Now Best Value AccessMedicine Full Site: One-Year Individual Subscription $995 USD Buy Now View All Subscription Options


text:
Here we have included some information about our present Parish Team. You can contact the parish office on 028 2564 1515.
Fr Paddy Delargy is a native of the Glens. After completing his post-primary studies in St MacNissi's College, also known as Garron Tower, Mgr Delargy, who is originally from Cushendun, Co Antrim, entered St Malachy's Seminary in Belfast in 1965 to study for the priesthood.
Taking undergraduate studies in philosophy at Queen's University from 1965 to 1969, Mgr Delargy continued graduate and post-graduate theological studies at the Pontifical Irish College in Rome.
He received a bachelor's degree in theology from the Pontifical Lateran University in Rome before completing a licence in theology at the Pontifical Gregorian University in 1974.
Mgr Delargy was ordained to the priesthood on July 7, 1973. He spent twenty years as a Lecturer of St Mary's College, Belfast and thirteen years as Principal of Garron Tower. He then spent seven years as Parish Priest of St Colmcille's, Belfast and came to Ballymena in 2009.
The Diocese of Down and Connor announced that Pope Francis has honoured Father Patrick Delargy, Parish Priest of Ballymena and Vicar General, and Father Joseph Glover, Diocesan Curia, by formally appointing them as "Chaplains to His Holiness", with the title of Monsignor. The appointments took effect from Tuesday 29 October 2019.
Fr Aloysius Lumala is a native of Mpigi, Uganda. He was ordained priest on 9 August 2008 in Lubaya Cathedral, Kampala by Archbishop Kizito. He came to Belfast to study in 2012 and worked in St Teresa's parish, Belfast before coming to Ballymena on 13 August 2019.
Fr Paddy McKenna is a native of Ballymena. He was ordained priest on 20 June 1970. He had a distinguished teaching career in Garron Tower before becoming President of Our Lady and St Patrick's College, Knock. After twelve years he retired in 1999 and became involved in full time ministry in the parish of Holy Rosary. He retired in 2019.
Barney McKeown is the Sacristan of All Saints' Church and looks after the Church grounds.
Breda Waterson and Teresa Crawford are the Parish Secretaries.
Dermot Crawford is the Sacristan of St Patrick's Church, Crebilly and the administrator of Crebilly Cemetery.
Bernie Keenan is the parish housekeeper.
Declan O'Loan is the Manager of All Saints' Parish Centre.
Angela Gibbons is the Administrative Assistant of All Saints' Parish Centre.
Claire Law runs 'The Old School Cafe' situated in the parish centre.


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All purchases made in store are final sale.
Orders may be cancelled or modified (size, color, style) within 24 hours of being placed. Order cancellations are not accepted after 24 hours.
Items Restricted from Returns: Bridal, Bridesmaid, Sale (sold as is), Clearance (sold as is), PRM Masks, and Custom Made gowns with our Design Team.
A Return Authorization Number (RA#) must be requested within 5 days of receiving your order. Returns will receive Store Credit, subject to a 10% re-stocking fee.
Returns must be shipped, in route to us, within 48 hours of receiving a RA#, and a tracking number provided/entered into our online Returns Center, or will be subject to rejection or a $15 late charge.
The customer is responsible for all shipping fees and shipping the return item(s) back to Mia Bella Couture. We suggest using UPS or FedEx for insured, safe receipt and your protection.
Dresses must be in their original, new condition with tags attached and no signs of wear, damage, alterations, stains or odors (i.e. perfumes, cigarette smoke, pet hair) otherwise they will be subject to a cleaning / tailoring fee. Original hanger must be returned or a $2 fee will be applied.
Shipping fees or duties from the original order are not included in Store Credit.
Shipped packages that are "Returned To Sender" (package refused) will receive Store Credit, subject to a 20% restocking fee with international packages subject to a 20% restocking fee and any return shipping fees and duties incurred.
Shipping and delivery dates are estimates only and not guaranteed. We are not liable for any delays in shipments or by shipping carriers. Risk of loss passes to you upon the carrier's delivery at your address.TO MAKE A RETURN REQUEST:
Within 5 days of receiving your order, request a Return Authorization Number (RA#) by clicking on the "Returns Center" tab at the bottom of this webpage and fill in the requested information. As soon as we review your request, you will receive email instructions and updates from us to help you return your item(s). Returns must be shipped back to us within 48 hours of receiving your RA# and a tracking number provided/entered in our Returns Center so we know your return is on the way.
To Request a Return: click here


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I am considering adding hull extensions to my 1994 Solaris Sunstream 40 in order to compensate for all the of the additional weight that is now being carried aft. I am very interested in hearing from those who have done something similar themselves, but my current thinking on the easiest way to accomplish this is as follows:
Take a plug off the lower portion of the existing transoms and topsides to the desired length/height for the extensions, cut out a section from the middle so that the forward end of the plug will line up with the exisitng transoms, fiberglass it back together and use it as a female mould.
Assuming this will work in making the mould for the hull form, I would also appreciate some advice on the lamination schedule and on gelcoating over epoxy resin. I would prefer to use epoxy for both constructing the hull extensions and attaching them to the existing transoms; having said that, I would also like to avoid having to paint the entire boat and would prefer attempting to match the existing gelcoat.
Any comments or suggestions?


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Federal Express is a SPAMmer
Yesterday evening I received an Unsolicited Commercial Email (UCE, aka SPAM) from Federal Express in violation of the California Professions and Business Code Section 17538.45.
Apparently Federal Express has taken to harvesting email addresses used in requesting tracking services and subscribing them to their marketing mailings lists without obtaining the permission of the owner of the email address (California law prohibits OPT-OUT policies, and requires that advertisers use OPT-IN methods).
Not only have I send a demand to Federal Expresses marketing campaign company and Federal Express demanding immediate payment of the fifty dollar fine specified by California Law; but I will no longer do business with Federal Express PERIOD. That means I do not ship via FedEx, and I do not accept packages via FedEx, which means I don't deal with vendors that use FedEx.


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MADISON, Tenn. (Sept. 1, 2011)—Marangoni Tread North America Inc. has completed a $10 million expansion of its Madison tread rubber plant that has added capacity for the firm's conventional Unitread tread rubber and expanded capacity for the spliceless Ringtread product.
The investment increased Ringtread capacity 30 percent, MTNA said, and created 20 new jobs. As production ramps up, MTNA said it expects to add eight to 10 more new jobs in the coming six months to the 75 there now.
Adding capacity for the Unitread product line makes MTNA a more full-service supplier, the firm said, and a total solutions company for independent retreaders. The company, a subsidiary of Italy's Marangoni S.p.A., offers a full catalog of retread equipment and plant supplies for customers in the U.S. and Canada.
Marangoni set up the Madison plant in 2004 as a base of operations to build a network of Ringtread retreaders. There are 26 Ringtread plants in operation in the U.S. and Canada.
MTNA did not disclose the plant's capacity or employment. Last year parent Marangoni S.p.A. said the project would add capacity for about 1,000 Unitread treads per day.
MTNA describes its Unitread product as an "innovative precure tread line" that is cured at lower temperatures than other conventional precure treads. MTNA supplies Unitread in cut-to-length sizes that are designed to minimize waste and reduce under-tread to run cooler in operation.


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Call 888-226-3483 to connect with the builder right now!
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1780 Via Lago Drive, Lakeland, FL 33810
Sales Agent Kimberly Young
Hours Mon 12pm-6pm; Tue-Sat 10am-6pm; Sun 12pm-6pm
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2020 Dream Home Savings
We never stop dreaming up ways to make home better. During our Dream Home Savings event, you will get huge savings plus exceptional construction, beautiful designs, one of the best warranties in the industry, easy financing, and an extraordinary c...Learn more »
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Use the VA benefits earned through your military service to buy a new home with $0 Down. See if you're eligible today!Learn more »
Picture yourself coming home to TerraLargo in Lakeland, FL. TerraLargo is a master-planned community located in a prime location in the heart of Lakeland. This community is tucked away off of Sleepy Hill Road and Kathleen Road, just a few miles from I-4 and HWY-98. The comfort and benefits of being just a few miles from I-4 is unbelievable, allowing for effortless commute times to either Tampa or Orlando. If you are searching for a community with even more ease and convenience, Publix, Walmart, Target, Sam's Club, and CVS are all less than 3 miles away.
As you drive through the front gates of this lush and private community, you will be astounded with the beauty and elegance of these new homes featuring tile roofs and paver driveways. Here in TerraLargo we offer single family homes in our Executive section or villa homes in our Solamor Villas section. Our homes range from 0 - 1775 square feet and start at just $0. Both our villas and single family homes are a part of our Landmark Series.
Our Landmark Series of new construction homes is comprised of home designs that are truly created for how you live today. Some homeowner design feature favorites are 42" upper kitchen cabinets, granite countertops throughout, stainless steel appliances, and so much more! The Landmark Series also now includes some smart home automation, encompassing a smart home controller, wireless security panel, 2 security door sensors, a video doorbell, a smart lighting switch, a WiFi thermostat, and more. We also include an industry-leading 15-Year Transferable Structural Warranty for added peace of mind.
You will ...
1780 Via Lago Drive
Lakeland, FL 33810
Lakeland, FL 33810
Lakeland, FL 33810
From $281,070
Lakeland, FL 33810
From $257,730
Lakeland, FL 33810
From $255,050
Lakeland, FL 33810
From $248,130
Lakeland, FL 33810
From $219,990
Area Schools
Actual schools may vary. Contact the builder for more information.
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For over 40 years, M/I Homes has been building new homes of unparalleled quality and craftsmanship. Founded in 1976, M/I Homes has established an exemplary reputation based on a strong commitment to superior customer service, innovative design, quality construction and premium locations. Since then, we've built nearly 100,000 homes and grown from a local family business to a national leader. But we still adhere to our founding values. Irving's son, Robert Schottenstein, our current CEO, sees to that. Listed on the New York Stock Exchange, M/I Homes serves a broad segment of the housing market including first-time, move-up, luxury and empty nester buyers.
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AKA(s): Scary MoVie, Scary Movie V,
The popular spoof franchise takes on a new round of horror flicks.
UPDATED: '42' tipped to edge out 'Scary Movie 5'
Tweet counts and analysis for the Week of April 8th Read more »
'Scary Movie 5' Delayed in Brazil
'42' Makes Baseball Movie History at #1; 'Scary Movie 5' Swings and Misses
ITALY: 'Scary Movie 5' Scores in Italy
Analysis: What Happened to the Spoof?
Ahead of this weekend's 'SCARY MOVIE 5', we take a look at the sub-genre's box office decline. Read more »
GERMANY: 'Iron Man 3' Beats 'Scary Movie 5' for #1
GERMANY: No Iron Man? No Problem: 'Scary Movie 5' Opens at #1
'42' Exceeds Expectations with $27.25 Million Debut
'42' Exceeds Expectations with $27.49 Million Start
'42' Comfortably Leads Monday with $2.23 Million
Long Range Punting - 'Kick Ass 2' dominates thanks to red band trailer
Long Range Punting - 'Les Miserables' first trailer impresses
A look ahead at the most notable films on the wide release schedule. Read more »
Long Range Punting - 'Paranormal Activity 4' dominates with new trailer
A look ahead at the most notable films on the wide release schedule. Read more »
'42' Passes $30 Million Mark on Tuesday
Overseas RoundUp: Top Ten Lists from the Major Global Markets


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Because of you, even in the difficult context of the Middle East, our Christian partners are still helping those in desperate circumstances turn their lives around.
Our partners provided emergency humanitarian aid to Syrian refugees,took medical services to remote and poor communities, helped people with disabilities get jobs, renovated unsafe housing, counselled teenagers suffering trauma, and so much more.
All of which is a direct result of your gifts and Prayers!
Annual Report and Accounts 2018
Annual review 2018
Impact Poster 2018


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The following are tips to help you use some of the most commonly asked features of the forum. This section will be updated as needed.
Multi-Quote that Post!
In order to reduce the amount of double/triple/quadruple postings, Werelist has a Multi-Quote feature which allows users to quote multiple people in a thread. Some users are unaware of this feature and often double/triple post when it's not necessary to do so. Here is a step-by-step guide on how to use this feature:
When you want to reply to multiple people in a thread, you will see the regular "Quote" icon located on the bottom right hand corner of the post. To the right of the "Quote" icon you'll see two icons that look like white pages with a question mark on it. Hover over the one that is directly to the right of the regular "Quote" icon and you will see "Multi-Quote This Message" pop up. Once you click it, the background of the white page will turn red. This will allow you to continue reading through the thread and the quoted posts will be saved until you are ready to reply.
Once you've quoted the amount of people you wish to reply to, go to the "Post Reply" and all of your quotes will be in one single post. Keep in mind this feature doesn't work in the "Quick Reply" thread box. For lengthy quoted posts, we ask our users to delete the chunks of texts and leave the specific parts of the quoted post you want to reply to. This helps keep the forums organized and also helps the other person know exactly what you are replying to.
** If you Quote a post that contains an image, please delete the image and reply to the text only! This helps saves space on the server. Thank you! **
How to Post Links
There are a couple of ways you can post links on Werelist:
1. Once you find a website you would like to share click on the entire website's URL address in the search bar of your internet browser. When you click the link it should highlight the entire web address. Right-click on your mouse and select "copy." Then you can simply paste the link in your post. For demonstration purposes, I will use the website "The Werelibrary". Here is what it will look like if you follow these instructions:
2. You can also go a few steps further to "clean up" the website address by using words instead of copying and pasting the web address like the one above. For example, I want to link to "The Werelibrary" but I only want it to display the words "The Werelibrary" instead of the full website address "http://werelibrary.org/site/". Here is what you do:
First, find the web address you wish to use. Copy the URL address and go on to the following steps: In your post, type out the words you want to use for your link (Example: The Werelibrary). Next, highlight the text you just typed. When you highlight all of the words, click on the "Earth" icon ( the round/blue icon and when you hover over it, it will say "Insert Link.") You will need to delete the default "http://" or else you will double that part of the web address and your link will not work. Next, paste the website's URL into the box. Once you click "Ok" the web address will be pasted to the words you typed and it should look like this:
The Werelibrary
There you have it! Two different ways to display links to websites.
Spoiler Tags: How to use them
No one likes to have movie or book plots spoiled if they have not read them yet. Please use common courtesy when posting character deaths, major plot twists, things like that. Creating spoiler tags is very easy to do:
When you are in the "Reply to Thread" box look for the "#" icon and click on it. You will need to replace the words "CODE" with "SPOILER." Now type in your spoilers between the brackets. If you need to Edit a post to add in a Spoiler code, you will need to make sure you click "Go Advanced" to see all the extra posting feature. Otherwise, you won't be able to click the # symbol to get the code, unless you manually type it into the quick edit post area.
You'll need to remember to keep the spoiler codes as close to your text as possible. If you leave a space it will not work properly. If you do this correctly it will look like this:
(Highlight the black block to read the text)
Hello! This is a Spoiler Tag! WHOOOOOOOO!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
Posting Images
Please keep the following rules in mind when posting images on the forums:
- Do not post images larger than 640 X 480. You may post larger images in The Gallery to show off your personal artwork but nowhere else please. If you need help resizing an image, please check out Web Resizer . This free service allows you to re-size large photos into smaller ones. As you can see from the example on the website, you don't lose quality of the picture, it just makes it smaller and easier for the forum to handle. Just remember to upload your new re-sized image to an outside image hosting website such as Photobucket , ImageShack , etc.
-Animated images are not allowed! If we see you post an animated image it will be deleted immediately and you will be notified. You may post a link to an animated image but do not post the image directly on Werelist.
- Do not go overboard with posting images on Werelist. This is NOT 4Chan!
- If you quote someone and it contains an image please delete the image as it takes up unnecessary space on the server.
- Remember to keep all images PG-13. No pornographic images are allowed.
- Please do not use the attachment feature to post images. When you use the attachment feature the images are stored directly to Werelist's server and it can cause problems. So please, don't use the attachment feature and instead use an outside Image hosting website to share your photos, or post a link to the photo you wish to share.


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London Post Offices and StreetsBernard Orna £50.00
London Post Offices and StreetsBernard Orna
Original General Post Office poster by Bernard Orna. The GPO was at the forefront of progressive graphic design in the 1940s and 50s. This poster is one of 50 different designs recently discovered from Parham Post Office, Suffolk. More information about this remarkable story can be found here


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A Room For Two: How Planning Getaways For The Sex-Deprived Became My Thing In College
When I attended college, it wasn't just someplace where students drooled over their desks as Professors droned on about inflation in Economics. It was also a place where many people found a market to exercise their newly discovered entrepreneurship skills and supplement their weekly allowances.
Me? I ran a niche charity service to help the needy. I planned Sexcapades.
In case you have no idea wtf I'm talking about, the dictionary defines it as:
I'll define it as – A getaway giving young lovers the privacy they crave, seeing as that's exactly what I did.
A window of privacy without all the waiting and worrying and occasional embarrassment of being caught in the act by your neighbourwali aunty.
So many horny teenagers, so little time. I loved it.
Because sexcapades take planning. Precise planning. I should know.
You need to carefully save up your pocket money to afford one. You need a list of affordable (cheap ) yet decent (not shady) hotels. You need transport. You need to track your menstrual cycle. You need a waxing appointment at the parlour and an hour with the razor to get the jungle down there in control. You need to pick out the perfect lingerie. You need to discuss all possible interpretations of the term – How far do you want to go?
You need to walk into a pharmacy and buy a box of condoms. (Which is way better than having to buy, or use, an I-pill btw!)
And lastly, you need an excuse to get out. The rest, I can help you with. This one you need to figure out on your own.
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WOW | Coffee Break
In this edition of Coffee Break, WOW celebrates the spirit of today's strong women. Anushka Shrestha interviews five successful females from different walks of life to know their perspective on what makes an independent woman.
wow photo file © Ram Tandukar/Gokul Shrees
Eeda Rijal
Co-founder, Sochware
Smriti Karanjit Manandhar
Asst. Professor/Head- Student Development, King's College, Westcliff University, USA
Bidhata Shrestha
Director, Radisson Hotel
Nishma Dhungana Choudhary
Nikita Acharya
Founder of UG cakes, Entrepreneur
Manita Devkota
Miss Nepal Universe 2018
How important is a man's bank balance and/or status to a woman today?
Eeda: Men and women complement each other. The status of a man affects a woman and vice versa. A family is run by both. Their responsibilities and duties are equally shared. Hence, the bank balance and status of both parties is important.
Smriti: Whether it's a man or a woman, having a better status and bank balance should be important to the individual himself/herself rather than just for the partner. For me, it doesn't really matter if a woman or a man has better status and bank balance. Both partners should perceive each other's success as a matter of pride and not feel inferior.
Bidhata: Women are now working and can rise up their own wealth and social standing so finding a man to elevate one's status isn't necessary. However, a woman with high status will likely try to find a man who is equal to her.
Nishma: If it is to get married, the only criterion that is required is love and respect for each other. A six digit salary does mean a responsible partner.
Nikita: Living in the 21st century, fighting for women rights, education and opportunity but eyeing a man's bank account means we are shaming the whole concept of feminism. Man's integrity, his values and morality matter more than his status. Also, his understanding, support and ability to uplift his partner matters more than his bank balance.
Manita: I think when choosing a partner in general, for both male and female, both attributes are important and they have become even more so as Nepal heads into industrialisation. Now supporting a family with only one salary has become difficult, and women are also working and earning income, and both men and women are starting to put more emphasis on a prospective partner's economic and social status. As a feminist, I do want to take this moment to defend the female gender on their mate selection trend. When selecting a mate, women tend to choose through an evolutionary lens because they have a higher parental investment. Women are driven to seek men who will be able to provide the necessary resources for the family's survival, especially during crucial times like pregnancy. It's no secret that mate selection in almost all parts of the world has found women prioritising certain traits: higher socio-economical status, well-educated, ambitious, and attractive appearance. Women mostly choose to marry men with higher status or income because their own ability to earn had and still is constrained by their disadvantaged status in a male-dominated society. Marriage is a way to upgrade the economic status of women. However, research shows that we will see a paradigm shift in mate selection as societies shift towards becoming more gender-equal, women's mate selection preferences will shift as well.
What matters more for you in your partner: financial status or social status?
Eeda: Financial status can be built in any term of life, but social status takes years of hard work. Once down, it is very hard to revive. Hence, for me, social status is more important when I look for a partner.
Smriti: If you look at Maslow's hierarchy of needs, social status and self-esteem rank much higher. Financial needs are important for survival and fulfillment of needs; however, social status earns respect. Thus, although financial needs and social needs are not mutually exclusive, I will still want my partner to have social status over financial.
Bidhata: Social status. As this for me is a simple index of income, education and occupational prestige. The financial status of a person does not guarantee certainty but a person with social status gravitates to be someone who is certain, someone with a clear vision and concrete mindset who makes decisions and sticks to them, a go-getter basically.
Nishma: I would say a mix and match of both. More than having a large bank account, I would go for with a big heart and dignified life.
Nikita: Social status with independent financials. There is no second thought that men with high social values are sexy. Yet, having a plan for the future, his ability to secure his family in need, and his independence is what makes a man complete.
Manita: What matters most is to have a partner who is talented and ambitious. If my partner is both of these things, the status he would gain would be through his achievements, not from how much money he has in his bank account or his caste. For me these things are irrelevant.
Are savings important?
Eeda: Indeed! Savings act as a backbone in human life. It gives confidence and empowers a person. Having good savings can make life secured. Even in case of an emergency, it is savings that actually come in handy.
Smriti: In a country like Nepal where social security is so volatile, it is always good to keep the safety net secured for unforeseen situations. Savings will give you security in case of health emergencies, higher education for children, and have a better life post-retirement.
Bidhata: For me, savings are important for emergencies and for going on vacations.
Nishma: Lately I have realised having money and not using it wisely can land you in problems. But only keeping it in your savings is another big blunder with finances. So use it wisely and smartly rather than just save is my choice.
Nikita: I love spending on experiences. Travelling, investing in fitness, books and food is what makes me happy and I believe it's important to invest in things that make you happy. But having said that, saving a certain amount of your income for the future is equally important. Knowing our finances, realising how we spend it and taking steps to secure for the future will definitely help contribute to making major life plans.
Manita: Everyone needs to save funds for emergencies, vacations, education and retirement. You can never predict what type of catastrophe will come about so it's important to set aside some money for emergencies. My personal favourite is the vacation fund as it is so important to take time off to getaway and relax the mind. Saving up for university is a must and education is a top priority for me. During high school, I worked as a waitress to save up money for university, something I am very proud of. I believe in saving for retirement as I want to still be independent in my old age and not be a burden to my children. It's important for me to have saved money for an elderly care centre and my medical expenses.
What makes a woman independent?
Eeda: There are various factors that make an independent woman. First, I would say is the confidence which is a result of education and skills. An educated woman with skills is empowered to get work. Secondly support from the family is very important.
Smriti: Education, family backup, leadership skills at work and home, and a well-paid job.
Bidhata: Her choices and her ability to follow through those choices with self-reliance, confidence and self-preservation.
Nishma: We need to broaden the concept of independence from just finances. It is more than having a bank balance. My biggest independence is having your own opinion on things. We often fall to the social norms that we don't agree to. That is complete dependence to the unwritten rules. I deny that. It is very important for us to go beyond someone else's idea of our life, be it with our clothes, appearance, career choice, hair colour, rights etc. Women are often guided to follow certain rules which are completely irrelevant. So for a woman to be independent she must acquire her confidence in all aspects of life.
Nikita: A woman is already independent since the day she was born, we just need to realise it. Independence for a woman begins right when she gains the sense of making choices of her own. Be it in choosing her own educational path, career path, or the love of her life.
Manita: I believe opportunities, the free will to choose them, and the confidence to pursue these helps to make a woman independent. Opportunities for education, career, suffrage, health care, relationships, and life experiences. An independent woman should show responsibility towards these opportunities, she must be assertive, and most important she must always care for herself.


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Mar 122019
Palmenberg's Sons New York – Patent March 27, 1894. I bought this from a local family that had a clothing store many years ago. It is very tall, measures about 90 high with finial. 1 center steel tube. Original finial is nickel plated brass and has wear and a slight bend. Base is solid heavy cast iron with a nickel plated brass cover, nickel is worn. Rack has 4 J. Palmenberg adjustable hangers that measure 18 long from center to end. They are 1/4 thick nickel plated brass. Each hanger has a unique ratchet mechanism for lowering and raising, they can be locked in position at different angles. By pressing a thumb latch it unlocks the teeth and lowers rack arm Mechanisms still work. 1 hanger has a crack but is still very solid, strong and able to be used with no problems(see last photo). The pole can be shortened without a problem. Racks can be moved up, down and sideways. They also can be removed by a hinged center mount and thumb screw. Rack mechanisms have wear, tarnish and a little play in pivot joints. Any questions just ask. The item "Antique 1894 JR Palmenberg Store Clothing Rack 90 Vintage Display pickup 17032″ is in sale since Wednesday, June 20, 2018. This item is in the category "Antiques\Mercantile, Trades & Factories\Other Mercantile Antiques". The seller is "clockworktoyshop" and is located in Dalmatia, Pennsylvania. This item can't be shipped, the buyer must pick up the item.
Sorry, the comment form is closed at this time.


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Fox News is under fire for running a story about a fake Vietnam War Navy SEAL who had created an enormous glass seal which he hoped to gift to President Donald Trump, according to the Washington Post.
Earlier this month on October 8, Fox News ran a story about glass artist and a supposed Vietnam War Navy SEAL, John Garafalo, who claimed to have won two Purple Hearts and more than two dozen other medals for his seven-year-long service in Vietnam as a member of the U.S. Navy SEAL. Fox News, apart from broadcasting Garafalo's interview, also ran the story on its social media pages, including Facebook, where it went on to generate millions of views.
But as it turned out, John Garafalo's claims were a complete fabrication. Not only had the man never won any medals, his records showed that he had never served as a member of the U.S. Navy SEAL, or in Vietnam. Despite all this, Fox News anchors heaped praise on Garafalo, calling him "a hero" and a "tough, tough man" during the segment.
"Garofalo is used to working under pressure," Fox News reporter Bryan Llenas told the viewers.
"The Vietnam War veteran served seven years as a member of the nation's first Navy SEAL team. He was awarded 22 commendations, including two Purple Hearts. You are a hero."
"God bless John Garofalo," the anchor chipped in. "We certainly hope maybe the president is listening."
A day after Fox News ran the story, Don Shipley, a retired SEAL who tracks down fake claims of military service, called the media organization and informed them about Garafalo's fabricated claims. Even Garafalo's own family contacted Fox News, contradicting and exposing the man's claims as bogus. Despite this, Fox News continued to run the story on its pages, angering Shipley.
"Fox News not withdrawing that story has drove me nutty," Shipley said, adding, "I don't know who has the balls in this day and age to do something like that."
He was the first to track down official documents which disputed Garafalo's claims about his service. Seeing as he did that Fox News was not retracting the story, Shipley contacted Navy Times with all the relevant documents. Navy Times cross-checked the authenticity of the documents with the National Personnel Records Center and Naval Special Warfare Command, and found that they were credible.
Fox News says it was duped by a man it highlighted as a decorated war hero https://t.co/C5VgCieDUg pic.twitter.com/JGcrgZypXv— Bloomberg (@business) October 20, 2017
When Navy Times confronted Garafalo about his bogus claims, he admitted the truth.
"It got bigger and bigger. What I did I'm ashamed of, and I didn't mean to cause so much disgrace to the SEALs," he said.
Fox News finally corrected the story after Garafalo's bogus claims were debunked, and released the following correction.
"All of Garofalo's claims turned out to be untrue. The fact is that he did not serve in Vietnam. He was never a U.S. Navy SEAL. Even though he showed us medals, Garofalo was not awarded two Purple Hearts or any of the other nearly two dozen commendations he claimed to have received, except for the National Defense Service Medal," it read.
[Featured Image by Alex Wong/Getty Images]


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Program Description
Advanced Customer Relationship Management
Key Information
- Course Code: MPRS105
- Duration: 5 days
- Fee: £2625
Course Outline
Understanding Customer Relationships
- Introduction to CRM
- Understanding relationships
- Managing the customer lifecycle – customer acquisition
- Managing the customer lifecycle – customer retention and development
Strategic CRM
- Customer portfolio management
- How to deliver customer-experienced value
- Managing customer experience
Operational CRM
- Salesforce automation
- Marketing automation
- Service automation
Analytical CRM
- Developing and managing customer-related databases
- Structured and unstructured data
- Data integration, warehousing and marts
- Knowledge management
- Using customer-related data
- Analytics
- Three ways to generate analytical insight
- Privacy issues
Realising the Benefits of CRM
- Planning to succeed
- Implementing CRM
- The future
Target audience
This CRM training is suitable for:
- Sales and marketing directors, managers, executives, practitioners and staff.
- Senior and mid-level managers who are involved in customer relationship management (CRM) programmes and system implementations, whether in a marketing department, the sales force or the service center.
- Contemporary CRM professionals who sell products or services, to consumers or businesses.
- Senior managers who realize that profitable customers are their company's greatest asset and seek guidance to retain them.
- Those who wish to understand the CRM landscape that covers the vastness between operational and strategic CRM, with an overview of customer-related data and data mining.
- Managers looking to take customer-centered strategies to the next level.
Learning outcomes
Upon completion of this customer relationship management course, you will be able to understand:
- What CRM is, the costs it creates and the benefits it delivers.
- The many varied contexts in which CRM is used.
- CRM technologies that are deployed.
- How CRM can be implemented.
- How CRM practices and technologies are used to enhance the achievement of marketing, sales, and service objectives throughout the customer lifecycle stages of customer acquisition, retention and development, whilst simultaneously supporting broader organizational goals.
What is Included:
- 30 hours of classroom-based training
- Apple iPad
Last updated Mar 2020
About the School
London Business Training & Consulting (LBTC) is the UK's premier business and management training and consulting service provider. We cater to both individual and organisational clients from all o ... Read More
London Business Training & Consulting (LBTC) is the UK's premier business and management training and consulting service provider. We cater to both individual and organisational clients from all over the world. Read less


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SAN FRANCISCO, Jan. 5 (Xinhua) -- Tech giant Google has said it will release security patches for its Chrome browser later this month to fix CPU flaws susceptible to hacking.
"Chrome's JavaScript engine, V8, will include mitigations starting with Chrome 64, which will be released on or around January 23 2018," Google said.
Future Chrome releases will include additional mitigations and hardening measures which will further reduce the impact of this class of attack, it added.
A Google research team announced Wednesday that it has discovered two hardware bugs, called Meltdown and Specter, which would exploit critical vulnerabilities in modern processors.
"CPU data cache timing can be abused to efficiently leak information out of mis-speculated execution, leading to (at worst) arbitrary virtual memory read vulnerabilities across local security boundaries in various contexts," the Google security team said.
Google said its browser users can remain protected against the two security bugs if they enable Site Isolation, an experimental feature which by default comes turned off in the stable versions of Chrome browser.
Other browser providers such as Microsoft and Mozilla have already shipped updates for their users to protect their browsers, Microsoft Edge and Fireforx, against the CPU flaws.


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Christopher Nolan e o cinema da inteligência artificial
A vida dos conceitos também pode ser breve e mesquinha, como a das pessoas. Em boa verdade, a...
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FS Direct: Training for Campus Primary Event Planners
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Guiding Students Most in Need
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Supervisors & Managers Roundtable: An Open Discussion
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Welcome Remarks
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Keynote: What is Cluster Pedagogy?
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Cluster Pedagogy and General Education
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IRB Review and Cluster Pedagogical Techniques
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Cluster Pedagogy and Fundraising
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Successes and Challenges of Cluster Pedagogy: Lessons Learned
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Force closes while viewing my custom channel.
Viewing a channel
Issues with viewing content in a channel
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18 comments
A pity no EU channels
It's all US orientated :-(
Yes - I realize we are very US focused with our content currently. We plan to expand this in the future. In the meantime -- Create some channels with content you like and let us know which ones should be promoted to Tier 1.
So far I haven't had any problems with viewing channels except for the occasional freeze up. The advertisements are a bit distracting though and can cause some lag when you're trying to read an article.
When I open a channel on my HTC Sensation, the top of the page is in the middle of the screen and the bottom is on top. It needs to be adjusted
I love the look of the app. Occasionally force closes on HTC Thunderbolt. Unless I'm missing it, an option to manually refresh a page would be useful. Several channels have not refreshed at all since I have had the app. Keep up the good work, I use both Tweetcaster and Friendcaster, I have no doubt you'll get this smoothed out.
I love the lay out of the app,the adds need to go
Is there something particular to how we have integrated ads that you don't like, or do you just not like ads? We plan to have a free version of the app with ads and a paid version without ads.
I think it is because they are on top instead of the bottem
Its not an add its the horoscope and stock market ticker that runs across the top. I read it can be turned off soon in an update sorry
You can close the ticker now -- tap the Up arrow at bottom of the ticker.
Freezing happened in many times.. App is too heavy yet..
Hopefully next Beta build will lighten it up a little. What type of device are you using?
I'm using SAMSUNG Galaxy tap 7 (p1000)
I have had the same issue, only downloaded the beta earlier today.
I'm finding the viewing of channels to be laggy and am getting occasional forced closes.
It would be nice to just have link add to a post. Rather than half page being taken up with."view web page" this would make the page nice and probably faster.
Also if the twitter channel just had avatars listed and the tweets were listed in line it would make viewing the info. Much faster.


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Inner Alchemy
Couples work is complex and rewarding. I am very discerning about the couples I work with as my style is fairly unconventional. I believe the relational intersection between 2 human beings in intimate connection is a sacred mirror in which each person sees their his/her gifts and wounds reflected in the other. When I work with couples, I encourage each person looks inward for the source of the friction in the relationship, and as in individual work, to journey back to childhood to heal the source of pain at the root.
I begin by having one or two sessions with each partner individually, and then work for as long as desired with the couple together. Using the inner tool of Focusing, partners witness each other as they dive into themselves for the source of challenge in the relationship. The intimacy of witnessing one partner search within for what has been previously projected onto the other is exquisite. Trust deepens and hearts open. It is an honor and privilege to work with couples willing to do this courageous work.
I am not attached to whether couples remain together or choose another path. My primary intention is that each person know him/herself more deeply, more intimately, and learn to express his/her deepest truth to the other.
The book that most accurately describes my approach with Couples is called Love and Awakening: Discovering the Sacred Path of Intimate Relationship, by John Welwood, and I encourage people who are interested in doing couples work with me to read it.
When the time has come for a marriage to end, sadly our culture treats this as a legal, rather than a ceremonial matter. If a couple has been joined for years or decades, the dissolution of the marriage is a huge event, and I believe one that should be handled very differently than is currently practiced. I call this process Matrimorphy. The word divorce comes with so many negative connotations I find it not helpful when describing what can be a very loving and connected process of changing the form of a relationship.
It may sound strange, but I love coaching couples through their divorce. Untangling from one another energetically is essential if one is to move on to another healthy relationship following the marriage. I help couples identify the unseen emotional agreements that have been at play during the relationship and support them to release these agreements. I help couples find the best possible outcome for resetting relationship with the former partner. At the conclusion of the process, I support couples to design a ceremony to bring their marriage to a sacred completion. This might be a ritual just for the couple, or might include children or family members, or it might be a larger community event, depending on the needs of the couple.


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Well, it's been a great two days for me in the Free Software and Linux Days at Bilgi University. There was lots of great talks around (which I have given two:). As always I have enjoyed a lot and learned different things again.
Especially Chris Stephenson's presentation about the functional programming was pretty cool and pushed me towards Scala instead of Java when using Play Framework (btw version 2.0 is out). What made me sad was the closing of the Computer Science department in Bilgi University. I mean, that's pretty absurd and terrible for Turkey. They are also shutting down, half of the Dolapdere campus. I mean what kind of a University does that?
Anyway, you should probably follow this video web site: http://video.cs.bilgi.edu.tr/ which includes lots of sessions. You can definitely find something interesting about it. Also some of this year's seminars will also take their place too soon enough.
Thanks for everyone who worked hard for this event to take place. See you next year!


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Happy Joe's Pizza & Ice Cream is located at:9919 W US Highway 20
You may use this page to send Happy Joe's Pizza & Ice Cream's address to any SMS/Text Message capable phone. A Smart phone with GPS may be able to show driving directions to this Pizza Shop.
The name, address and phone number of Happy Joe's Pizza & Ice Cream will be sent to the Phone via the carrier's SMS gateway.
You may see a Map of Happy Joe's Pizza & Ice Cream, get Driving Directions or view a list of all Pizzeria in Galena.
Here is a list of top Pizza Franchises in Galena:


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After chronicling her empowering and emotional climb to the top of Mount Kilimanjaro on social media late last month, Mandy Moore has permanently commemorated the momentous occasion with a tattoo. The This Is Us star took to Instagram on Thursday, April 12, to show off the new mountain-like ink on the side of her right foot with the caption "the mountain. Forever commemorated. Thank you @winter_stone for the reminder of what we accomplished."
Since undertaking the massive climb in March, Moore has been quite open about the impact the excursion had on her life. On social media, she's shared pictures and videos from the climb and summit including her curly "mountain 'dos" and primitive shelters.
The tattoo — designed by L.A.-based artists Winter Stone Tattoo — is a delicate outline of the rigid terrain, which the "Candy" singer said she has "dreamed the dream of climbing" since she was just 18 years old. She called the feat, which was done in partnership with outdoor company Eddie Bauer, one of the "most rewarding and challenging experiences" of her life.
As it turns out, this isn't first foot tattoo Mandy has gotten in remembrance of something — though it certainly seems a bit more sentimental than her last. While filming a project in 2015, the actress revealed on Instagram that she has a sperm-shaped design inked on the inside of her heel that she got as a "silly joke" with her bandmates nearly a decade earlier.
She captioned the pic "that moment when you realize the silly joke tattoo you got with your band 8 years ago means that your sweet stunt double has to have it drawn on too," and she explained during an interview with Seth Meyers in 2016 that the she and her crew got matching tats after a tour in response to a running joke that had developed.
"Well, about 10 years ago, I was on tour with my band. I had my own room to shower in … all of the guys in my band shared a day room. Their one rule was nobody was allowed to do … that thing in the shower," she told Meyers, referring to masturbation. "It became this big joke."


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Monthly Archives: "April 2016"
DIY Designer Hutch Makeover Part 1: Mixing and Applying a Custom Scumble Glaze
In part 1 of this two part series, we are going to take you through the process of creating and applying a custom tinted Scumble glaze. We chose to create a dark glaze that would add richness and depth to the new paint finish on this vintage cabinet, but with Scumble you can createContinue reading »
Create an Abandoned Chateau Finish with Crackle Tex!
The many images that have been circulating on Pinterest of forgotten castles and chateaus crumbling away from the inside out, continue to intrigue us and capture our imaginations. Once majestic, ornate faux finished walls and doors that have been abandoned and left to age naturally overtime serve as great inspiration for paint finishes that crossContinue reading »


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Forget the Sahara Desert, Peru actually has the highest sand dune in the world! Cerro Blanco sand dune, located in the Sechura Desert in the south of Peru, measures 3,860 feet from the base to the summit. It towers over the quaint desert oasis town, Huacachina, and the best part of all is that you can ride dune buggies for hours and up to the top of the dunes and then strap a board to your feet and sand board down it all the way to the town below.
(Source: Huffpost.com)
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New Hampshire Boy Scouts Enjoy Rifle Shooting
NRAblog 04.10.12
The Boy Scouts of America are one of NRA's most active Youth Cooperative Organizations, who utilize NRA firearms training for their shooting sports programs. Troop 270 from new Hampshire is no exception. Thank you to Scoutmaster Mike Michaels for sending the following report and photos from Troop 270's day of rifle shooting.
Dunbarton, NH – Boy Scout Troop 270 of Pembroke, New Hampshire brought out 18 Boy Scouts and 10 adults for a great day of rifle training and shooting fun. Weather was no concern as the boys were donated indoor range time and target rifle usage from Pioneer Sportsmen Inc. of Dunbarton, New Hampshire. Pioneer is a private club for pistol, rifle and archery with a beautiful and well equipped indoor range.
New shooters just starting the Rifle Merit Badge went through the NRA FIRST Steps rifle course with Instructor Scott Lane. Experienced boys proceeded directly to the range to complete their groups. One of the toughest parts of earning the Merit Badge is shooting five, 5-shot groups at 50 feet that can be covered by a quarter. Many of the participants were able to complete the requirements. All the boys had a great time with over 1600 rounds fired.
The troop shoot was organized by Scoutmaster Mike Michaels who has been a firearms enthusiast since the first day he shot a .22 rifle as a young Boy Scout. Michaels is noticing that there are not enough kids involved in the shooting sports but yet all of the scouts he meets are very interested in shooting.
"We are providing the opportunity for youth to get proper training. We want to guide their firearms interest in the right direction and see them pursue other safe shooting activities", Michaels said.
Instructor Mark Dumas noted, "We are not just helping the boys, many adults attended the class and we made sure they got to shoot as well". Parent Aaron Smart wrote, "Thank you for all your work with the boys, I also had a really great time!"


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I build off that strong initial spark, that bright idea, to deliver my clients with creative solutions that are impactful. From strategy, concept, design to development my focus remains on my clients objectives delivering quality creative and commercial success.
Have a project in mind? Want to talk through a brief for ideas?
I specialise particularly in the scoping, conceptualising, designing and development of corporate and marketing communications – but love to be involved in any interesting and creative project! Here are just a few examples.
Deallus Communicationsanne2020-07-05T09:50:13+01:00
Wolters Kluwer PowerPoint Templateanne2020-07-02T13:04:13+01:00
Epaccsys Websiteanne2020-07-02T11:55:29+01:00
Wolters Kluwer Tax & Accounting UK Websiteanne2020-07-05T09:55:20+01:00
Wolters Kluwer Exhibition Designanne2020-07-05T09:56:21+01:00
Lane4 Brand Projectanne2020-07-05T09:57:45+01:00
Exchequer Brand Projectanne2020-07-05T10:00:43+01:00
Lane4 Marketing Communicationsanne2020-07-05T10:04:18+01:00
Wolters Kluwer Tax & Accounting Communicationsanne2020-07-05T10:05:20+01:00
"Anne is so talented and a true pleasure to work with. She was an integral part of my company's rebrand process – from generating our new logo and look, to designing our new website, to creating our messaging and brand guidelines, she added crucial value throughout the entire process. I would highly recommend her to anyone looking for a thought partner and creative talent when undergoing any sort of brand changes!"
Maggie Zelasko, Marketing Manager, Deallus


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Iron Maiden bassist speaks on the "impossible" state of play for rock music today
"I think it's tougher than ever"
Steve Harris of Iron Maiden has voiced his concerns about the current state of rock music and the lack of opportunity for young bands today.
Speaking to Kerrang behind the scenes at their The Book of Souls tour, bassist and songwriter Steve Harris speaks on the "state of play" for rock musicians today.
After noting that bands back in the 1980s were privy to "more possibilities', Steve mentions that it's incredibly difficult for bands to get noticed nowadays.
"It's very, very tough. I think it's tougher than ever", Steve begins. "Now there are so many bands and not so many outlets for it. And it's tougher than ever to earn a crust doing it, too. I sort of feel sorry for bands in a lot of ways."
He continues, "Sometimes it's the luck of the draw, and being in the right place at the right time, and all that kind of stuff. You've just got to keep chipping away".
Harris then gave some props to bands who he reckons have overcome the odds. "Avenged Sevenfold have come through, Biffy Clyro's another one's that come through to headline festivals. Those two are the ones that spring to mind the most".
"Even with us, if we finally hang the old guitars up, you think, 'Who's going to come and take over?'"
Read more: Iron Maiden announce new wave of UK tour dates
Recently, Iron Maiden vocalist Bruce Dickinson shared details on how his cancer diagnosis changed his vocal style.
The post Iron Maiden bassist speaks on the "impossible" state of play for rock music today appeared first on NME.
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As one of the self-regulatory organizations for the financial industry, FINRA monitors 99% of equities & 70% of options in the US, including NASDAQ and the New York Stock Exchange (NYSE). This task includes collecting and parsing through immense amounts of data. On an average day, these markets have around 30 billion events. High volume days can be even more: We've processed 75 billion events from a single day of trading.
All this data needs to be sorted and used by various groups inside of FINRA. The Extract, Transform, and Load Group (ETL) is the team that works to bring in all this data and process it in less than a day. Hundreds of people rely on the data provided by ETL and look at it on a daily basis.
Here's how they make it possible to use market data to protect investors.
To begin, exchanges send data from trading to FINRA. Different exchanges send the data differently, but most send the data in batches throughout the day.
Many exchanges, like the Chicago Board Options Exchange (CBOE), send their data via API. This data goes directly to the cloud and is stored in AWS's S3. It's critical that we keep both unprocessed and processed versions of the data for record purposes as a regulator.
Once data has been gathered, the ETL group needs to process the data. This has three important stages: validation, transformation, and publication. With EMR Hadoop clusters, OOZIE, and Hive, all three stages happen quickly in the cloud, often in 12 hours or less. The ETL group begins by validating the data. At this stage, they focus on semantics, file names, and the details of the data. They also provide feedback to markets about whether or not the data was sent in the proper formatting. Details such as file name can seem small, but when processing so much data, these details must be correct.
From there, the ETL group transforms the data. Even when the data passes validation, each market's raw data has their own formatting and set of symbols. For easier use internally, the ETL group takes all the various markets data and standardizes that format into one or more flat objects.
Finally, the market data is published to internal consumers. There are two types of publications. One is the standard publication that is common to all groups in FINRA. However, some groups have some specific requirements for their work. These custom pieces take up about 25% of ETL publications.
Yet, there's always work toward further standardization. The ETL group works to make the standard publication more robust. This helps keep customized publication work low so they can focus on their larger goal: to move from batch and scheduled processing to processing data as it arrives without any delays.
Trading on American financial markets continues to grow and become faster. With rising demand, the cloud has been the solution to the 60-70 terabytes of data we need to process each month. On premises, processing market data could take 24 hours, sometimes even longer depending on volume of trades.
In the cloud, we've been able to dramatically reduce that time. The ETL group begins processing at 9 pm and finishes by 9 am the next day. Stretching this work over up to 1500 transient Hadoop clusters a month makes the quick turnaround possible. While faster than previous on premises processing, we're still working to shift all market data processing to the cloud.
However, the shift to the cloud does come with hurdles. The new technologies we're using, such as Hive and AWS, are younger open source tech compared to the legacy systems of the past. There may be bugs which can affect the data, which can be a large problem for a regulatory organization.
In addition, part of the transition must include security. The paradigm for how we think about security has radically changed in the cloud. This requires time to ensure no individual or organization is put at risk.
Finally, processing this much data in the cloud requires a new way of thinking about cost. Whereas before we focused on how much could we fit into one proprietary processor, today we can have infinite processing at any time. Using spot pricing from AWS has been great to keep costs down, sometimes getting nodes as cheap as 25 cents a day. Because spot pricing changes, processing costs can dramatically change day to day or quarter to quarter.
This change requires less of a technology shift but a change more for teams and project managers inside the ETL group. Still, with a working cloud system in place, the transition continues to have more and more market data sent, processed, and stored in the cloud. By July 2016, we're expecting all the ETL processing will occur in the cloud, continuing the work of processing data quickly to protect investors.
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