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Scientific Research
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Comparison of Sensory Processing and Semantic Differentiation in Peoples with Schizophrenia, Multiple Sclerosis and Alzheimer's Disease ()
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Semantic Differentiation
1. Introduction
Criterion B for schizophrenia gets more attention in DSM-5: "Level of functioning… is markedly below the level achieved prior to the onset". This is not a criterion for schizoaffective disorder (This is apparently unchanged from DSM- 4).
American Multiple Sclerosis Association [1] [2] see that Multiple sclerosis is an immune mediated process where an abnormal response puts the immune system against the central nervous system including the brain, spinal cord and optic nerves.
Memory refers to recollection something from past and it is usually done consciously. Perhaps, sensory processing is the most essential componet of psychological, that forms the base of how people perceiving and reacting to environmental stimuli. New evidence shows that people, process the sensory information, in different ways. This means that some people are more sensitive than others to have sensory information [4] [5] .
In a study by [6] under the title of "sensory processing in Schizophrenia; missing and avoiding information", three groups of people, first group people with schizophrenia, second, patients with bipolar disorder, third, normal people as control group, were compared on basis of a four components model of adult sensory profile with sensory sensitivity, sense avoid, low registration and sense searching variables that are described as behavioral responses to sense. In compare with normal group, all the two groups of patients with schizophrenia and bipolar disorder, had high score in sense avoid. Schizophrenia group had higher score in low registration and lower score in sense searching rather than healthy group. There were not any differences between the two groups of schizophrenia and bipolar disorder. Cording to the result of this research, patients with schizophrenia have desire to lose of available sensitive stimuli. When drivers actually appear, they are often avoided.
Initial descriptions of sensory sensitivity, McGhie & Chapman [7] about attention deficit in patients with schizophrenia, including some personal reports, that describe the noises loudness, color brightness, distraction and disorganization in patient. Sensory gate insufficiency, that is measured by pre-trauma and latent inhibition such as techniques, also denotes the inability to filter out irrelevant information in this disorder. But Brown & et al. [8] in their studies didn't find any meaningful differences between patients with schizophrenia, patients with bipolar disorders and normal people, in view point of sensory sensitivity. But the avoidance of feelings in people with schizophrenia and bipolar disorder was higher than normal. The schizophrenic patients frequently fail to response and ascribe meaning to stimuli. Their performance in reaction time tasks is an example of slowed response in schizophrenia. Return responses (the urge to go back to previous responses) can also be another example of low sensory registration in patients with schizophrenia. In connection with sense searching Brown & et al. (Ghamari and Bashar poor, 2009), concluded that schizophrenia and bipolar disorder groups were significantly obtained lower scores in sense search. According to the results,since the extreme sensitivity and inhibition to sensory stimuli and also impairment in social skill which is the result of sensory pro- cessing disorder, is a very important aspect of schizophrenia and partly to major depressive disorder, therefore, identifying the style of sensory processing in patients with these disorders, can help to precise identify of impairment.
Rotenberg, quoted by [9] in a study on patients with schizophrenia showed that, cognitive impairment and inability to make appropriate use of past information, are connected with perceptual input or information processing and formation of signs that need to the left hemisphere activity.
Mehrinejad et al. [10] write that several studies have shown that the style of repressive character, negative emotions, inability to talk about feeling, over assimilation and hysteric characteristics with a weaker immune system and emotions expression and thoughts depended on excitement, are related to immune system performance improvement.
In a study by [11] under the title of "Sensory symptoms of multiple sclerosis: a hidden reservoir of morbidity, the following results reports: Sensory symptoms were more common in MS patients than in controls, and differed in severity and quality. There was however a strong correlation between the total number of sensory symptoms reported and the presence of disability in the MS patients. Conclusions: Sensory symptoms are common in MS patients. Pain syndromes, transient neurologic events, Lhermitte's phenomenon (to feel an electric shock symptom in the arms and legs downward by shaking and moving the neck), fatigue, respiratory symptoms and vertigo were present significantly more frequently in patients with MS than in a control population and contributed to subjective morbidity. Future clinical trials assessing therapy in MS might include sensory symptoms as secondary endpoints to capture this "hidden reservoir" of disease morbidity.
2. Research Hypotheses
Sensory processing in patients with schizophrenia and multiple sclerosis (ms) is different.
Sensory processing in patients with schizophrenia and Alzheimer's is different.
Sensory processing in patients with multiple sclerosis (MS) and Alzheimer's is different. Semantic differentiation in patients with schizophrenia and multiple sclerosis (ms) is different.
Semantic differentiation in patients with schizophrenia and Alzheimer's is different.
Semantic differentiation in patients with multiple sclerosis (MS) and Alzheimer's is different.
3. Methods
Our research method was causal-comparative. Statistical population were patients with schizophrenia in Mirzakochak mental hospital and patients with multiple sclerosis and Alzheimer's disease that are kept by formal caregivers in welfare centers or by informal caregivers in families in Rasht city of Guilan province in Iran. 45 persons with MS, Alzheimer's disease and schizophrenia (in each group 15 persons) were randomly selected by accessible sampling method in 2014. Disease is independent variable and sensory processing and semantic differentiations are dependent variables. Then, subjects were asked to response to sensory profile questionnaires to measure of Sensory processing memory and to ozgood semantic differentiation questionnaire to measure of Semantic differentiating processing. This test is made after extensive research and application of factor analysis by Ozgood. This feature is made of 10 contradictory attributes and the participants will be asked to describe themselves based on 10 attributes. In this method Ozgood measures the emotional sense of the feelings against the words. The subject must score himself (or herself) with these ten characters, for example (Active-passive, quiet-restive) on a 7-points Likertscale [12] . Coefficient of Cronbach's Alpha of this test is 0.85. Coefficient of internal consistency of subscales of sensory processing test were reported between 0.60 to 0.78 and Cronbach's Alpha coefficient of this test for total scale is 0.87 and for subscales of low registration, sense searching, sensory sensitivity and sense avoiding are as 0.72, 0.65, 0.75 and 0.71 [13] . Then raw data were analyzed by multiple analyses of variance (MANOVA) with using of spss16 software.
4. Results
Results of Table 1: Given that semantic differentiation mean of schizophrenia is 23.93 and multiple sclerosis is 26.20 and Alzheimer is 26.26 (maximum in three groups).
Results of Table 2: Given that total sensory processing mean of schizophrenia patient is 37 and multiple sclerosis is 37.40 and Alzheimer is 48.80 (maximum in three groups).
Results of Table 3: shows that for example low registration variable mean of schizophrenia is 9.20 and multiple sclerosis is 8.20 and Alzheimer's disease is
Table 1. Descriptive information about semantic differentiation in the three examined groups.
Table 2. Descriptive information about sensory processing in the three examined groups.
Table 3. Descriptive information about the components of sensory processing in the three examined groups.
10.87 and so on.
Results of Table 4: Given that significance level of p = 0.47 > 0.05, variances are equal.
The result of Table 5: In firstrow, given that significant level equal to p = 0.001 < 0.01, so there is a significant difference between the groups in sensory processing.
Table 4. Levin test for sensory processing.
Table 5. Results of the multivariate analysis of sensory processing.
In second row, given that significant level equal to p = 0.341 > 0.05, so there isn't a significant difference between the groups in semantic differentiation.
5. Discussion and Conclusions
Average sensory processing and average semantic differentiation are different in three groups of patients with schizophrenia, multiple sclerosis and patients with Alzheimer. An obvious conclusion is that the sensory processing in patients with multiple sclerosis and Alzheimer's is better than the group with schizophrenia. This issue is consistent with the inhibition reaction by patients with schi-zoph- renia that cited by [5] in literature. Totally patients with Alzheimer's disease had significantly better performance in sensory processing. Patients with schizophrenia had lower performance than the other two groups. The semantic differentiation in patients with multiple sclerosis and Alzheimer's is better than the group with schizophrenia. This issue is consistent with the studies of [10] [12] [13] in literature. Totally patients with Alzheimer's disease had better performance in semantic differentiation. Patients with schizophrenia had lower performance than the other two groups.
One of the major limitations in sample size is illiterate or low literacy people which make it difficult to gather information and need to give sufficient information and required training to individuals to fill the questionnaires which are time consuming. In the present study variables such as gender, marital status, education, and the severity and duration of illness are not included.
Given that sensory processing in patients with Alzheimer was better than the other tow groups, therefore, it is better to use of sensory processing and its enhancement to treatment and rehabilitation of these people, it means that must be used of sensory processing to compensate other memories.
Because sensory processing isn't in a desirable condition in patients with schizophrenia and multiple sclerosis (MS), so it is necessary that the people who are at high risk of developing the disease or the initial stages of the disease, must be acted to improve their sensory processing.
Given that semantic differentiation in patients with Alzheimer was better than the other tow groups, therefore, it is better to use of semantic differentiation and its enhancement to treatment and rehabilitation of these people, it means that must be used of semantic differentiation to compensate other memories.
Because semantic differentiation isn't in a desirable condition in patients with schizophrenia, so it is necessary that the people who are at high risk of developing the disease or the initial stages of the disease, must be acted to improve their semantic differentiation.
Conflicts of Interest
The authors declare no conflicts of interest.
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It would appear to me that we are due for a considerable technological backlash. The advent of personal devices has proceeded at such an alarmingly accelerated pace that has exceeded our capacity to fully interpret their real meaning and implication. If we start, however, to turn on the billion-dollar marketing machine and come to realize that there are very real consequences for a family of five to each trot out of the house with a cellphone and iPod, then we might harvest a resistance to our programmed consumerism. I am not certain when it was exactly that we stopped being citizens and became consumers, but I would suggest it likely began in the 1950s, thanks to the post-war boom and the gentle sounds of domesticity oozing so seductively from the darnfangled new thing called "Television".
Indeed, for the first time we could see what a good family was supposed to look like and--most importantly--what a good family should own. As much as the cognoscenti love to derride television, daytime programming had a profound effect on social conditioning, and it helped establish the norms of a nuclear and productive family that we are still struggling to redefine. And closely linked to that norm creation was the emergence of advertising as an indelible influencer of personal worth and value. The much-maligned soap opera owes its very existence to a desire to market household products to women. I would argue that Oprah owes her ascendancy to the decades of captive housewives nurtured through early daytime programming. That Oprah might seek to empower and educate her audience is certainly subversive in its intent, even when she undermines herself with rewards of excessive consumerism.
So, the revolution may well be strapped to your belt. When commentators speak about Facebook, for example, they miss the point. The Facebook software is not the story. The fact that millions of people have adopted the software in the hopes of connecting with other people is the story, and is what we ought to concentrate our attention on. In the desire to sound bite this contemporary phenomenon so many folks conflate Facebook with the relationships on its pages. Facebook is merely a tool, not the conversation. I have no loyalty to Facebook. If it disappeared tomorrow I would move on and not think twice. I adopted Facebook simply because it was the more dynamic and visually interesting option among the early competition. If Facebook asked me to subscribe (like Classmates.com) I would not pay. The other point that should be made is that, given all the options, Facebook is actually the least effective way in which to communicate with one's friends. And yet, it has millions of users despite its inherent limitations and security issues.
If the typical consumer-citizen can be likened to the poor truck in the photo above, it is not surprising to read in the style sections of our newspapers that the dinner party is making a serious comeback. This clamour for visceral contact and communication makes a great deal of sense, although I supect the key agents of this revival are over-35. Meanwhile, the savvy IM one another, all the while checking out a YouTube video they posted earlier, looking up to spot the top 5 countdown on MuchMusic, while they conference on their cell phones, which beep to show them a trailer for the sure fire blockbuster of the year. Is it any wonder that in the midst of all this cacophany, we sometimes need to reach out and actually touch someone?


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"Hey dude, where's my car" — never again will you have to utter these words, courtesy of a new Google Maps feature that lets you save your parking location on a map.
Originally launched as part of a Google Maps beta (and only on Android) in March 2017, the feature just went live on Android and iOS.
To activate the feature on Android, tap the blue dot and choose "Save your parking," and a label will appear on the map, showing you where you parked. You can even add a note to give yourself more precise instructions for later, add a timer (with a 15-minute reminder), send your parking location to a friend or save an image of the spot. Read more…
More about Parked, Parking, Google Maps, Tech, and Mobile


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Unfortunately, higher education faculty and staff in general, and student affairs professionals in particular, are behind the curve in their use of information technology. Student affairs professionals are only starting to become aware that they should learn about the technologies that students have already integrated into their lives.
It is imperative that student affairs professions understand these technologies and learn how to implement them to
enhance student learning
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facilitate communication This volume examines recent research on how information technology is affecting college student development and explores ways in which institutions are responding to increased demands for using emerging technology in supporting students.
This is the 124th volume of the Jossey–Bass quarterly report series New Directions for Student Services , an indispensable resource for vice presidents of student affairs, deans of students, student counselors, and other student services professionals.
Each issue of New Directions for Student Services offers guidelines and programs for aiding students in their total development: emotional, social, physical, and intellectual.
Reynol Junco, Dianne M. Timm
1. An Introduction to Technologies Commonly Used by College Students 3
Reynol Junco, Gail A. Cole–Avent
This overview of the most popular technologies among college students today provides insight into how students use technology and the role technology plays in communication and educational pursuits.
2. Have You Facebooked Astin Lately? Using Technology to Increase Student Involvement 19
Greg Heiberger, Ruth Harper
Astin s model of student involvement provides a way of looking at the current and potential use of Facebook.com to enhance student engagement.
3. Technology Use in Campus Crisis 37
Jeanna Mastrodicasa
This chapter examines the impact of technology, such as cell phones and social networking sites, on students and administrators during a crisis, using examples from recent years, including Hurricane Katrina and Virginia Tech.
4. Students Technology Use and the Impacts on Well–Being 55
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This review of the latest research on how technology use can affect students psychological health and well–being also outlines areas for future research and suggestions for practice.
5. Blogging in the Academy 71
Shane Nackerud, Kurtis Scaletta
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6. Privacy and Social Networking Sites 89
Dianne M. Timm, Carolyn J. Duven
The authors look at how students perceive privacy as it relates to social networking sites and the role staff and faculty play in using this medium on college campuses.
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Student affairs professionals will benefit from having a thorough understanding of the technologies available and how students are using them, in addition to staying informed as new technologies develop.
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Day 3: Navigating Icy Sidewalks and Driveways
But, there are some simple things you can do to stay safe while walking outside.
Hartley Wright spent the day shoveling his brother's driveway. But it hasn't been so easy.
"Slipping and sliding from time to time and where it's melted yesterday and frozen over today is a little harder to walk on then you would imagine," said Wright.
There are a couple of easy things you can do to make sure you are safe when you are walking outside.
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You don't have to be doing anything risky to fall on the ice.
"Whether they're taking their trash out or just trying to get out to their car.a few slips and falls a few hip fractures," said Dr. Adam Beckett of University Hospital. "We've seen unfortunately."
Mid-Missourians are going to have to deal with the snow and ice because it's not going away any time soon.
And Beckett says the E.R. has been especially busy these past couple of days, not only because of people slipping on ice but also the number of people getting sick.


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Archaeologists have unearthed a rare find: a giant black granite sarcophagus sitting at the bottom of a 16-ft. pit in the Egyptian city of Alexandria. It is the biggest sarcophagus ever found in the city where Alexander the Great is believed to be buried.
Alexander the Great was a king of the ancient Greek kingdom of Macedon. He was only 33 years old when he died in Babylon. The location of his tomb is an enduring mystery — his corpse was stolen before its burial. Early scrawls have revealed that he was reburied in Alexandria after being initially interred in Memphis.
This sarcophagus was discovered while clearing the site for a new building. Under Egyptian law, all sites must be excavated before anything can be built on them. The sarcophagus was found in a hidden tomb five meters below the ground.
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Archaeologists finally opened it two weeks after it was dug up
Archeologists were shocked to find the mummy still intact inside the eerie 9.8-ft. sarcophagus. It will give scientists an opportunity to learn more about our ancestors.
The researchers under the Supreme Council of Antiquities will now work on identifying the body. The chances are very good that it could be Alexander the Great!


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On today's Heart Of Mind Radio, Host Kathryn Davis will speak to Princess Maria Amor, international Humanitarian and founder and president of We Care for Humanity and Donna Stein, representative for Friends of Clearwater regarding the upcoming Water Festival to take place on Sunday August 23rd.
Also mentioned are two important events taking place this weekend: ECOFEST! on Sunday August 16th and Kathryn's Qigong Class in Prospect Park on Saturday August 15th. (More information on these events below)
Princess Dato'Seri Maria Amor DK1, Princess of the Royal House of Balai, is an International Humanitarian Icon, founder and president of We Care for Humanity, an international Non-profit organization and creator and chairman of the G.O.D. Awards held at the United Nations.
She is also the recipient of DARJAH KERABAT- a royal award given to royalty and dignitaries, A Seasoned Diplomat, Peace Advocate, Television Host, Marketing Mogul, Entrepreneur, Producer, Paint-Artist, Fashion Designer, Event Coordinator and Endorser.
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Producer/Host- The Traveling Princess
Goodwill Ambassador- Acid Survivors Foundation, India
We Care for Humanity G.O.D. Awards The Royal Kingdom of Sulu
Donna Stein is a long time activist for social and environmental justice. She was President of the environmental education organization NYC Friends of Clearwater for several years and now a current board member. Fracking and fossil fuels has been a major focus. Donna came to NYCFC to help with their 1st Annual Water Festival and stayed. She is here today to talk about the 7th Annual Water Festival.
Donna is active in NYC Safe Energy Campaign working on closing Indian Point, promoting renewable energy, and efficiency; Trade Justice trying to get the word out and stop so called trade deals which is really the biggest threat to our health, environment and liberties we are facing . Currently Donna works for Green Energy Times, a resource publication focusing on renewable energy and sustainable living.
Sunday Aug 23rd 2015 – Annual NYC Friends of Clearwater Festival 2 – 7 PM
This year's theme is "Efficiency is Sexy!" Everyone appreciates solar and wind, but efficiency and conservation changes the conversation! – Celebrating the music and activism of RAY Korona. Free concert, wonderful Environmental educators and potluck!
Speakers: Marilyn Eile, Indian Point Safe Energy Coalition; Waldon Fishman, NY Solar Energy Society & Green Energy Times, Tom Wysmuller, International Climate and Energy lecturer; Tim Judscon, Nuclear Information & Resource Service, Tim Keating, Rainforest Relief; Friends of Ray; Ken Gale, NYC Safe Energy Campaign and host producer of Eco-Logic on WBAI FM
Musicians: Ray Karona Band; Ivice; Barry Kornhauser, Ellen Davidson and Gina Tlamese; Judy
Gorman, NY Metro Raging Grannies; Jeanny Hurwitz, Peter Pasco, NYC Streetslingers; Chris Land and others.
LES Ecology Center on the East River, park entrance on Cherry St
Show off your cooking or bring something store bought to share for our potluck.
10 AM – 6 PM BROADWAY@42ND-44TH in Manhattan, NYC
IT'S ALL FREE! For info call 212 496-2030, or go to Ecofest.org
- The SEOTO (Sources of Energy Other Than Oil) Display includes alternative fuel vehicles that are suitable for New York City: hybrids, electric, biodiesel and ethanol as well as New York City fleet vehicles, hybrid taxis and the latest fuel cell vehicles.
- The Solar Powered Stage will host a variety of concerned artists who will provide entertainment for the public including The Dharma Bums, Guy Besserrete, the Solar Sound Band and R & B artist Al Smith. We will also welcome back Precise, environmental rapper, as well as the Great NY Tap-In for Clean Water with many of NY's finest tap dancers.
- Activities for Children include Recycling Olympics, Eco-magic by "The Amazing Ken", Face Painting by Marina environmental crafts supervised by Lillias, an art exhibition created by New York special needs children, judged by artist, Peter Max..
- A beautiful authentic Tibetan Sand Mandala created by the Venerable Lama Tenzin Yignyen, a close friend of the Dalai Lama.
- Explore delicious food and entertainment, green products, exhibitors, seminars and workshops on sustainability and energy efficiency!
Qigong in Prospect Park with Kathryn Davis
Saturday August 14th, 1 PM enter at Grand Army Plaza entrance
We will gather from 12 – 1 PM in front of the main public library at Grand Army Plaza and head into the part at 1 PM (if it rains class will be re-scheduled)
For information call: (347) 480-1694
Kathryn also offers private healing sessions at her Healing Space in Bay Ridge Brooklyn: 110 Bay Ridge Ave ( 2nd floor walk up):
Email contact and websites:
QigongOnLine.net – email@example.com
HeartOfMindRadio.com firstname.lastname@example.com


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I bought this bike new in 1986 and used it for winter training. I had it it repainted and completely rebuilt about 5 years ago, so it's in great shape and only has a few dings. It has a CycleItalia logo on the downtube, but the original head badge is still there and the serial number SL505649 is still visible.
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Where & When: Pottsville Beach Neighborhood Centre and outreach locations within the Tweed Shire
Phone Kym on Tuesday to Friday on 0455 911 715 and Belinda on a Friday on 0413 879 279
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Uber partners with NASA to develop flying taxis by 2020
US: In order to make its ambitious flying car project a reality Uber has signed a deal with NASA to provide the technology to make the cars city-friendly by 2020. According to the deal, NASA will help Uber to develop both aerial and unmanned traffic management systems for the taxis, which means taxis that can fly at low altitudes over urban environments.To make this dream a reality, the company has also partnered with manufacturers to develop the cars and said it would integrate them into its user network… (Read More)
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SpaceX rocket engine explodes during testing in Texas
US: In a setback for SpaceX, one of its latest rocket's engines exploded due to reasons not identified as of yet. An investigation has already been launched to determine the cause of glitch and malfunction which caused the explosion, Elon Musk, the founder and CEO of SpaceX said. No one was injured during the 'qualification test' of the Merlin engine in McGregor, Texas, but the unexpected occurrence shocked everyone. "No one was injured and all safety protocols were followed during the time of this incident… (Read More)
Rolta's announces Q2 results; registers growth of 3.4%
India: Rolta has announced the unaudited quarter two results for the fiscal year 2017-2018. In an announcement, the company declared the consolidated revenue for Q2 FY-18 at INR 7.49 billion against INR. 7.24 billion in Q1 FY-18, registering a growth of 3.4% quarter on quarter basis. On the other hand, the consolidated EBITDA for Q2 FY-18 at INR 2.47 billion against INR 2.52 billion in Q1 FY-18, registering a decline by 1.9% quarter on quarter basis. Consolidated profit after tax for Q2 FY-18 at INR 0.33 billion… (Read More)
AirMap and Kespry partner for safe, compliant drone flights
US: AirMap and Kespry today announced a partnership that brings AirMap's best-in-class airspace intelligence, including airspace advisories, wind, and weather, to Kespry's leading automated UAV solution. The new integration empowers Kespry's industrial customers to fly with confidence, ensuring that each mission can be flown more safely, more efficiently, and in compliance with relevant airspace conditions and requirements. Kespry manufactures the autonomous Kespry drone, part of an end-to-end… (Read More)
Google-UNHCR interactive project shows destruction wrought in Syria
The United Nations High Commission on Refugees (UNHCR) has roped in Google to create an interesting project called Searching for Syria. The interactive and user-friendly project uses a wide variety of data and imagery — including aerial images, videos, satellite imagery, demographic data and other footage such as testimonials of refugees — to comprehensively take stock of the Syrian war. The website, devoid of any partisan political undertones, provides information about all facets of Syria before the war… (Read More)


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St Anne's Veterinary Group Blog
You've probably seen in the news recently about the increase in illegal puppy imports over the last 3 years. According to the BBC officials found 208 illegally landed dogs in 2014, rising to 688 in 2016. People aren't aware of the conditions the puppies are born in. With most of the puppies being born in terrible conditions on puppy farms where the welfare of the animals are second to the money and profit. Some sellers even set up fake home situations to make it appear that the puppies have grown up in a family environment.
Currently imported puppies must be at least 15 weeks old, if younger and reported they could be taken away from their new owner. There are calls to increase this age to 6 months as this is a more clearly identifiable age, whereas 15 weeks can be a bit hard to judge the age.
Many people rush into buying a puppy without doing their homework, several hours spent researching breeders and breeds will save you money and heartache in the long run. Many of the puppies from puppy farms will have false documents and may not have had vaccines. The amount of heart broken families I have seen mourn the loss of their puppy farm puppy after the Parvo virus has engulfed them.
Even East Sussex County Council are getting involved and trying to get people to be aware of these things when purchasing a puppy. We even see people who have done the right thing and found someone who is advertising the puppies with full documentation and microchips, worming and vaccinations and get there to find out the breeder lied. Most responsible publications for adverts won't accept the advert unless these stipulations are met, so the breeders lie in order to get their advert accepted. By which time a prospective owner has arrived and fallen in love with their new puppy when they get the news, making the difficult decision to then leave the puppy or to accept it without any paperwork and having to sort out the worming, chip and vaccination.
So what can you do before getting a puppy? Well I think most people have a favourite breed that they have always wanted but it's just making sure you're well informed before purchasing it. Did you know we offer free pre-purchase puppy consultations with our qualified nurses? We can talk about what breeds might best suit your lifestyle, what breeds are pre-disposed to having what conditions so you're going into it with your eyes wide open!
Brachycephalic (short nosed) dogs such as French Bull dogs and Pugs are very fashionable right now, but having such short airways and lots of skin folds can lead to chronic problems. Other breeds are known for having heart problems or joint problems. Certain breeds have higher insurance premiums which would need to be taken into account.
The Council recommend not purchasing puppies from pet shops, car park's or service stations. Always ask to see the mother of the puppies, if excuses are made and things seem a bit suspicious then do not purchase the puppy. Reputable breeders are usually picky about where their puppies go and will not let go of their puppies to just anyone. Always ask to see relevant documentation of vet checks, first vaccination, worming etc. Be suspicious of people selling different breeds until you are sure of their credentials.
If people aren't buying from these irresponsible breeders then there will be no trade for them to keep going.
If you would like anymore information then please call 01323 640011. We all want the best for all animals. The number of dogs that end up being re-homed because the owners didn't realise how much of a financial burden they would be has increased.
Author: Menna Field RVN MBVNABlog topics


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he new Star Trek: Discovery series was highly anticipated and has premiered amidst concerns that it is being overshadowed by Seth MacFarlane's, also highly anticipated, The Orville. First impressions are not entirely negative, just mostly.
I laid my bar of expectations on the floor and somehow Star Trek Discovery didn't even clear that.— Daniel Hardcastle (@DanNerdCubed) September 25, 2017
We centre around Michael Burnham; a human whose parents, we find, were killed by Klingons. She was subsequently raised by Sarek, Mr Spock's Vulcan father. Flashes of her past, including her first moments meeting Capt. Georgiou, are very inciteful; they inform and progress the plot. However, they don't make me like Burnham. I understand her motivations for her actions, but it doesn't make me think that she did the right thing. Quite the opposite.
I really liked how different the beginning was from any other series opener in the franchise. Spanning over two episodes we are thrown, just like the crew, into a situation way bigger and more consequential than we imagined. The directing style is reminiscent of J.J. Abrams and this may have been on purpose. It is pleasant to watch, the character development is good, it's interesting and the story held me. But I'm unfortunately struggling to find any standout elements that gripped me into continuing watching.
Discovery is set ten years before Kirk but therein lies some issues which I'm finding difficult to get past. At one point Burnham actually reasons with the computer. If we are to believe we are pre-Kirk should the computer not be less advanced? You could never reason with it on this level – everything was very much black and white. Burnham negotiates a grey area.
I feel like we are covering old ground and exploring some of the same issues which have been touched on in previous series. Although Burnham is human she was raised as a Vulcan and thus has this perpetual internal struggle between logic and emotion. We have been here before. Also, we leave the story with Burnham facing life imprisonment. This brought up suggestions that her character may have a similar deal to that of Tom Paris in Voyager. What more is there to explore within this theme?
I'm having some trouble with Star Trek Discovery. Specifically the apparent story parallel between Michael Burnham and Tom Paris. [thread]— Marie (@buknerd) September 26, 2017
I also dislike the Klingon re-design. I'm not an expert or anything but looking back at Lt. Worf's ridges in Next Generation and his obvious body and facial hair is a huge jump from the hairless, multicoloured, many-ridged Klingons we see here. I'm aware a huge amount of time has passed by, which included a period of illness which altered the Klingon's appearance, but the progression is not obvious, especially when you look at the change is traditional dress – very ornate.
This series needed to be careful. It needed to be different enough to springboard off the success of the recent movies and attract new fans to the franchise. It also had to adhere enough to canon to keep older, very serious fans happy and supportive. I'm not sure it has successfully achieved the latter.


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Therapeutic massage impacts the body as a whole. In this research, we demonstrated that iPSCs could possibly be differentiated into Leydig-like cells utilizing the defined molecular compounds, which expressed membrane receptor: LHCGR, cholesterol transporter: SCARB1 and STAR, and steroidogenic enzymes: CYP11A1, HSD3B1, CYP17A1, and HSD17B3, had the similar gene expression profiles with LCs, and produced testosterone.
Stem cells are gaining attentions within the regenerative medicine particularly after the establishment of human ESCs in 1998 31 and human iPSCs in 2007 32 Human iPSCs are considered to own similar characteristics to human ESCs 32 As iPSCs can handle the immunological and moral issues associated with human ESCs, they symbolize potentially effective method to cell transplantation-primarily based regenerative medication.
All users are urged to always search recommendation from a registered well being care professional for prognosis and solutions to their medical questions and to ascertain whether the actual remedy, service, product or remedy described on the website is appropriate in their circumstances.
WebMD does not provide medical advice, analysis or treatment. This is a compilation of articles with details about all features of dental well being, proper from oral care, dental implants, gum diseases, and way more. On this research, we report a novel protocol, to our knowledge, which is the first to reveal that iPSCs had been capable of be differentiated into testosterone-producing Leydig-like cells by few defined molecular compounds.
Organized interventions to enhance well being primarily based on the rules and procedures developed by means of the health sciences are offered by practitioners trained in medication , nursing , vitamin , pharmacy , social work , psychology , occupational remedy , physical remedy and other health care professions Medical practitioners focus mainly on the health of people, whereas public well being practitioners contemplate the general health of communities and populations.
Health is a useful resource for everyday life, not the target of living; it is a optimistic concept, emphasizing social and personal assets, in addition to bodily capacities". Wang, Y. et al. Oncostatin m inhibits differentiation of rat stem leydig cells in vivo and in vitro.
Teerds, Okay. J., De Rooij, D. G., Rommerts, F. F. & Wensing, C. J. The regulation of the proliferation and differentiation of rat leydig cell precursor cells after eds administration or daily hcg treatment. Health advantages of dates may be derived by eating a handful everyday, either contemporary or as dried fruits, entire or chopped, as a snack or a part of a meal.
Not only is desert residing a leisured and less expensive alternative to metropolis life, it has some amazing well being advantages too. However they mentioned fast food eating places ought to begin to increase adjustments to advertise healthier consuming, comparable to decreasing portion sizes. As potassium does not get saved within the physique, a regular consumption of dates will regularly replenish the physique and support in maintaining a healthy nervous system and the appropriate stability of the body's metabolism.
Murono, E. P., Washburn, A. L., Goforth, D. P. & Wu, N. Fundamental fibroblast progress issue-induced increase in 125i-human chorionic gonadotropin binding to luteinizing hormone receptors in cultured immature leydig cells is mediated by binding to heparan sulfate proteoglycans.
The frequent individual with a well being criticism now has more instruments at his or her disposal to help with treatment and prevention. Morris, I. D., Phillips, D. M. & Bardin, C. W. Ethylene dimethanesulfonate destroys leydig cells within the rat testis. Eat mindfully, specializing in how your body feels.
Government bureaucrats just cant react quick sufficient to know what number of specialists to rent or the place vital medical tools needs to go. If there's a life or demise state of affairs there may be cause why foreigners come to the USA when things are dire and they are rich.
Food regimen
It is estimated that over forty million staff within the United States needed to obtain emergency medical therapy for office-associated injuries in the 12 months 2003. 30 This implies that the positive well being benefits of pure house in urban neighborhoods needs to be taken under consideration in public policy and land use. Protecting issues cleaner round the house, opting to minimize or stop smoking altogether, or exercising more are just a few of the many different ways taught in public well being education to fight sickness and enhance one's lifestyle.
For most individuals, good health care means having a primary-care physician, knowledgeable who assists you as you assume responsibility in your overall health and directs you when specialised care is necessary. Odeh, H. M., Kleinguetl, C., Ge, R., Zirkin, B. R. & Chen, H. Regulation of the proliferation and differentiation of leydig stem cells within the adult testis.
Well being Teaching On Vimeo
Whereas dependable health data may be present in pharmacies, doctors' clinics and community well being centres, it can be troublesome to find trusted medical data elsewhere.
WebMD doesn't present medical advice, prognosis or remedy. The inhabitants in query can be as small as a handful of individuals or as massive as all the inhabitants of a number of continents (as an illustration, in the case of a pandemic ). Public well being has many sub-fields, but usually includes the interdisciplinary categories of epidemiology , biostatistics and well being companies Environmental health , community well being , behavioral health , and occupational health are also important areas of public health.
Takahashi, K. et al. Induction of pluripotent stem cells from grownup human fibroblasts by defined elements. The information and supplies contained on this web site are not supposed to constitute a comprehensive information regarding all points of the remedy, product or therapy described on the web site.
Shan, L. X., Zhu, L. J., Bardin, C. W. & Hardy, M. P. Quantitative evaluation of androgen receptor messenger ribonucleic acid in developing leydig cells and sertoli cells by in situ hybridization. It may be difficult to observe a fully vegetarian food plan and keep healthy.
Crawford, P. A., Sadovsky, Y. & Milbrandt, J. Nuclear receptor steroidogenic factor 1 directs embryonic stem cells toward the steroidogenic lineage. Households can be taught the links between physical exercise, healthy consuming and little one security. The A to Z index of medical illnesses contains hyperlinks to topics with information about that particular well being condition.
Little Black Book Of Health, Magnificence And Wellness Practitioners
Not only is desert residing a leisured and cheaper alternative to metropolis life, it has some amazing well being benefits too. A kind of therapeutic massage remedy Flavia found after her own being pregnant, Flavia has made it her private mission to understand women's our bodies throughout the varied phases of life and wellbeing and returned to college as an adult to study human physiology and to find out about lymphatic drainage.
At 21 days after publicity to EDS, the rat body weights had been notably decreased just on day 7. Subsequently, the physique weights in iPSC-LC transplanted rats or PBS injected rats started restore, and had no considerably completely different with PBS injected rats with out EDS therapy on day 14 and 21.
Illness, Diet, Healthcare & Extra
Massage impacts the physique as a complete. Compared with other organs, testis is immunologically privileged fifty one To research whether the iPSC-LCs have the power to outlive and function within the interstitium of rat testes in vivo, we transplanted the iPSC-LCs into an EDS‐treated rat mannequin, an androgen deficiency mannequin, as beforehand described 52 EDS is an alkylating agent, which has selective pro-apoptotic effects on LCs 27 Approximately 2-three weeks after a single dose of EDS, newly regenerated LCs might be noticed inside the testicular interstitium fifty three Approximately eight-10 weeks later, the LC population returned to its unique dimension and had restored its skill to supply testosterone fifty four Based on these results, we collected the testes of the cell‐transplanted rats 21 days after EDS administration, at which period level the regenerated LCs appear slightly, to look at the state of the transplanted cells.
Since massage animates the tactile sense, the body's main sense, it brings folks into the here and now and away from rigidity generated by fixed preoccupation with issues. Public health refers to attempting to cease a disease that is unhealthy to the community, and does not assist in lengthy life or promote your well being.
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The cure for most cancers remains to be a way off however it's something that science expects to occur presumably within the subsequent few decades; medical research continues to advance in it is conflict with this disease that plagues humanity. It can be crucial that you simply perceive any dangers involved in stopping or changing a medical treatment. Cancerous cells might have been reworked by radiation or poison for instance and this creates genetic abnormality in those cells which then continue to grow and divide.


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Poolside is an indie band hailing from Los Angeles, California. The driving forces behind the band are Filip Nikolic and Jeffrey Paradise, who love to create music to complement great weather and anything fun in the sun. Their debut album Pacific Standard Time was released a little while ago and was met with positive vibes--great-weather vibes, if you will. Poolside's style and sounds are tailored for the lackadaisical enjoying the breeze brushing their hair aside, or reclining on an inflatable tube in the middle of a pool. With summer knocking hard on the front door, their relevance is at a maximum.
Their latest released single "If We Make It" does little to deviate from the defining characteristics of Poolside's debut album. Within this particular tune, you'll find yourself tossed into modest synths and retro-sounding percussion coupled with funk-driven bass making its statement in the background. Dreamy vocals lather all the elements together into yet another good-feeling soundtrack for your summer shenanigans.


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What kind of church makes an apostolic statement that is genuine, authentic, sent of God, and changes the culture in which it resides? Where is such a statement being made? The goal of the apostolic church is not to be recognized as apostolic. The goal of the apostolic church is to be recognized as Jesus. This will be a church, a body operating in the fullness of His word.
This is not an in-depth calculation of the matter but more of a idea building exercise to challenge us to consider the apostolic in its intent within the body and the elements of its necessity for the revelation of the kingdom as it manifests through believers in the church to the creation.
"Apostle" Defined
Simplistically, apostle translated from Greek means "sent one." This was a term used in the Roman empire for a general that was sent to change the culture of a conquered country to Roman.
The term seems to have been used because Jesus sent out His disciples out into the world to preach the kingdom. The calling in was for the purpose of the sending out:
And He went up on the mountain and summoned the those whom He Himself wanted, and they came to Him. And He appointed the twelve, so that they could be with Him and He could send them out. Mark 3:13-14 emphasis mine.
But you will receive power when the Holy Spirit has come upon you; and you will be my witness both in Jerusalem, and in all Judea and Samaria, and even to the remotest part of the earth. Act 1:8
So we understand an apostle is one who is sent to preach the kingdom and in doing so the culture is attuned to that of the kingdom of heaven. I believe it safe to say in our consideration that an apostle is a culture changer.
We know from the Word and even from history the results of the apostles and apostolic ministry in the earth. There has always been a remnant of the apostolic call and gifts in the earth, but only recently has there been an increased desire for such a consideration to be apprehended by the faith.
As stated in an earlier post, same as the gifts, such as the apostolic and prophetic are being restored–and thus furthered in their fulfillment in the earth–there will be the attachment of naivety and misunderstanding concerning the elementary, and therefore secondary knowledge of the operation of the gift.
Apostolic Constitution
So we have the jury's verdict in our persuit of the nature of the pure apostolic form that "Jesus saught." We conclude that apostles are sent ones. Therefore something that is of an apostolic constitution is something sent of heaven. I have included an excerpt from Apostolic Essence, a previous post that details this conclusion:
Matthew 16:13-23
Jesus asked His disciples who people said that He was (13-16). The response by the disciple was a natural one. They knew He was supernatural so they compared Him to other supernatural men. This sounds good, but their vision was still on men and not on God. They needed to lift their vision higher, so Jesus asked them the question again; "But who so you say that I am?"
Peter had his vision on God. He was not comparing Jesus to other men. Jesus was more than a man. He was God manifested in their midst, yet it still required the unveiling of a mystery to see this. Jesus was revealing in such a way to show that the unveiling of the mysteries of the kingdom come from God, and not from man. The vision must not be surface level, and must be a heavenly eternal vision. This is where, at this time, Peter had his sights. Therefore he could make the proclamation that this Man was the "Christ, the Son of the living God." This is the same as saying; "Here is God!" This is monumentous; this is perplexing; this is a clarion call sounding throughout the earth: creation acknowledging and returning in faith & revelation to its creator. Here is the announcement to the heavens and the earth, the creation and the universe HERE IS GOD! (This revelation should be present within us everywhere we go, if indeed we are The Church.)
Do you realize what it took for Peter to speak that out (17)? What it took for Peter to confess that? Peter who was a Jew in a nation where all men where looking for this? This was risky; to look at this man, Jesus, as the Son of God. Yet all the others missed it. God was staring them in the face, but because they were looking at the appearance of a man, they missed the revelation needed to understand that this was the appearance of God.
Thus you have the revelation of two paradigms: the vision of God and the vision of man. This is the core of the issue in determining that which it in initiation is defined as; the way of God or the way of man. This is precisely why Jesus came, to save us from our own way and to show us His. Ours is influenced by the devil, and it is the way to death. His way is influenced by the Holy Spirit, and is the way to life. The very first thing to understand in the church is that Jesus is Lord, and from this revelation, we must build the church in the Spirit, by further revelation from Him, and not try to build it ourselves.
The revelation that is sent of heaven is the fabric for the church that Jesus is building through His people in the earth. I fathom that it is safe to reason that a church that is functioning or living this way is apostolic indeed.
Apostolic Function
We have now somewhat developed an idea for the terms apostles andapostolic. With that we can now proceed with the determination of how they would look and function in the church today.
One of the demarcations of an apostle in Scripture is the signs of an apostle.
The signs of a true apostle were performed among you with all perseverance, by signs and wonders and miracles. 2 Cor 12:12
For a church to be apostolic and for her apostles to be true, the signs will be present. And in the case of the apostolic, the supernartural in essence is a part of their very being. Down in the core of who they are beats the sounds of the heart of heaven. They burn for the heavenly realities to not only be revealed, but also overtake the earthly ones. This is the culturization of the earth with the kingdom of heaven. The fact that they are heavenly makes them different, makes them real. Their buisness card is the exercised demon and the healed body. I understand that all who walk in these gifts are not apostles and even in an apostolic work, however, according to Paul, true apostles absolutely live this out as part of their function and existence.
The road is beginning to take route. With somewhat of a foundation laid for us to now ponder apostolic considerations. What–in context of Scripture in accordance with the plans of God in the Spirit in our generation and times–is the apostolic influence within the body as it matures into fullness?
Apostolic Words
Some food for thought of how to go about considering the apostolic: we can preface words or ideas, even things God has shown us to derive their meaning and influence within the apostolic matrix. Some examples: apostolic fellowship; apostolic church; apostolic foundations; apostolic origins; apostolic function; apostolic expression; apostolic anointing; apostolic generations; apostolic lifestyle.
The list could go on and on, but do you see how the dynamic of the word changes when considering it in an apostolic light? Each one could be a study in and of itself.
Apostolic Journey
This is where I am presently at in my own journey into the knowledge of the apostolic.
What is the apostolic? Our hearts pound for the truth. I don't just want to be apostolic or prophetic. I want the Father's intention for those gifts to spring the life in my heart they are designed to edify and equip me and us with. They are not the goal; Jesus is. And He gave us gifts to enable us to reach fullness in Him.
I have been on a ten year quest to be purged deeper with meaning of the matter from my relationship with the Lord only to find out that the answers come in the form of the purging experience of life itself. I do feel I am more acclimated with the subject and I am eager to share the glimpses I have seen.
Apostolic Galaxy
One thing that I have come to realize is that in the exploration of a galaxy, the understanding of a planet is necessary in the understanding of the galaxy. However, the planet alone does not describe the galaxy. I feel this where we are in the consideration of the apostolic, which why I am eager to encourage the body of Christ to search out and identify the encapsulation of its meaning.
So, for an encapsulation of the apostolic on my part, ask me again in 10 years and maybe you will get a more profound paragraph with fewer words and more impact. I hope to encounter other explorers of this apostolic galaxy, ones who have visited planets I have yet to hear of, and show me things I have yet to see. And as the fellowship of revelations comes together, a picture will be painted for the next generation to follow and believe.
Faith is a vast exploration, the validation of life and existence. There is more of God every second of every day. Consider the sand and the stars, countless as they are, they are not but one breath, one thought of His majestic glory. O that we may see and gain wisdom into His majesty. All life comes from Him. In its most basic description, the apostolic is something sent, borne in His bosom, created, original, awesome and glorious. This is the place we must reside. The exploration of Him is far more grand than that of galaxies and His gifts to us are grand and majestic; gifts given to make us more like Jesus.
I think this is a safe angle from which we can glean, grow and discover the meaning of the apostolic. This has been a conglomeration of thoughts that I hope you were able to follow. Volumes could and are being written on the matter but I hope we can surf the wave coming out of God's heart that reveals the apostolic.
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FIAP have adopted a new NATURE definition for photo competitions and one for WILDLIFE too.
The PAGB are adopting these definitions immediately for the Club Championships in October and are likely to adopt them permanently after that. In their turn the L&CPU are more or less bound to use them since they need to be able to enter pictures of ours into the PAGB competitions.
So it cascades to us. The committee will consider the new rules next week but, since the changes are not likely to affect our workers, I think it likely they will be adopted.
So what are the changes? You can read the PAGB eNews version HERE.
Subject: I always wish these organisations would find someone with at least GCSE Biology to help them, as the definitions are always clumsy and unnecessarily wordy. To cut straight to the point though, yes, zoo shots are allowed BUT you need to make sure there is no evidence of enclosure because man-made structures can only appear if they are part of the animal or plants "natural" environment. A zoo shot makes the subject a NATURE shot as opposed a WILDLIFE shot, where the organism is truly wild and free. Garden plants are excluded but only if they are hybrids (by which I assume they mean plants especially bred for gardens), shots of specimen plants in a botanic garden ARE allowed (but avoid any signs of enclosure). Domestic animals are still excluded but landscapes could be acceptable if they depict a recognisable geological or biological feature.
Naming: You are not asked to name the organism! However, I cannot see how the rules can be met if you do not, otherwise how could anyone judge that it is a depiction of x, y or z? Certainly scientific names are not needed. In fact it does not say that the species even has to be correctly identified, but you would be risking down-marking if any of the judges spot the mistake.
Cloning is NOT allowed, nor montage. Minor adjustments used to be permitted but now NO adjustment to the picture contents except dodging and burning, cropping and removing camera generated blemishes. HRD and focus-stacking is permitted.
Narrative comes before pictorial, but quality must be high. I assume means that a picture with better content beats one which is just prettier!
At present the PAGB does not have any competitions with a WILDLIFE section, but watch out for mention in the rules in future. It will basically mean "no zoo shots".
Beginners will be puzzled by the fact that many things they are advised to do; such as make the organism a certain size in the frame, make sure all the organism is in the frame, are not included. Well, they never have been. Things like this are just preferences and preferences can change. For example since digital camera have a higher capability for capturing action pictures which make use of this are likely to do better.


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Kid Destroys Dollar Store PART 2
The Accurate Source To Find Transcript To Kid Destroys Dollar Store PART 2."
[Kid Destroys Dollar Store PART 2]
[Enforcer:] Source: LYBIO.net
Merry Christmas, how about that! Merry Christmas!
[Woman (Background):]
There you go Christmas time for you.
[Camera Person:]
Now I gotta…
I don't care –
[Camera Person:]
I gotta make sure I record it cuz my dawg ain't did' nuthin' to him – you feel me. Yo, just in case somebody say he did somethin' to him, I got it on camera he did nuthin' to him.
[Woman (Background):]
Ain't nobody did….
[Camera Person:]
Ya, you feel me, so it's on camera he ain't did nuthin' to him.
[Enforcer:] Source: LYBIO.net
Uh huh – we ain't goin' nowhere. We ain't goin' nowhere. We ain't goin' nowhere. You's was in there tearing up people's store, you weren't [carin'] – so stay yo ass right here until the police come – you said you wanna go. Chill out.
[Man (Background):]
They coming don't worry. They be here in a minute.
(indecipherable) I told you I won't get a hold of yo ass. I told you.
[Man (Background):]
They will take you far away.
Walk around here doin' crazy shit, people ain't got time for that shit.
[Woman (Background):]
Stay right here – do you see all that shit you done did? Do you see all that shit you done did? Alright, I'm glad you don't give a fuck – cuz I don't either.
[Man (Background):]
It's vandalism.
What your mamma done did to you, I don't know. I don't know Jit, I know she done did something to you and you came up here to —
[Kid (Jit):]
You can go home.
You ain't no –
[Kid (Jit):]
You ain't wanna go home.
[Kid (Jit):]
You stupid.
They stupid. That's fine.
[Kid (Jit):] Source: L Y B I O . N E T
You are stupid.
Kid Destroys Dollar Store PART 2. I gotta make sure I record it cuz my dawg ain't did' nuthin' to him – you feel me. Complete Full Transcript, Dialogue, Remarks, Saying, Quotes, Words And Text.


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Lindberg U.S.S. Missouri BattleshipMilitary Kits : Military Ships : War Ships
Lindberg Military Kits1:900 Scale
U.S.S. Missouri Battleship
Lindberg 70869
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Item DescriptionHere we have the Lindberg U. S. S. Missouri Battleship in 1:900 scale. This model kit comes complete with easy to follow instructions guiding you through the build. For this Lindberg kit glue is required, and we highly recommend paint to get the best results. Recomended for ages 13 and above.
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