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Overcome Work-Related Pain: 6 Ergonomic Products For Your Home Office
19 June 2017
For those who work from home or even those who constantly bring their work home from the office, it's vital that you invest in ergonomic products to increase your wellbeing and health. Some of the major benefits of using ergonomic products while you work include reducing work-related injury or illness and reducing the time taken to complete your tasks. In other words, effective ergonomic products can increase your productivity while minimising your pain due to prolonged immobility. Invest in these six ergonomic products for your home office as soon as possible:
Reduce leg strain with a footrest
Your feet and legs need to be properly supported to avoid long-term health problems due to bad circulation. A footrest helps to decrease varicose veins and swelling, relieve pressure on your lower back, prevent blood clots, and reduce pressure on your legs. If you're short, a footrest also helps to keep your feet flat on a surface so your weight could be properly distributed.
Avoid bad posture with an adjustable standing desk converter
Ideal for smaller desks, an adjustable standing desk converter is a small yet effective addition to your home office. Featuring a palm rest and pneumatic adjustment, the product helps you to avoid bad posture, in addition to lowering the risk of cancer (particularly colon and breast cancer, which can be caused due to prolonged sitting), cardiovascular disease, Type 2 Diabetes and other metabolic problems, and obesity.
Reduce eye and neck strain with a monitor arm
Seeing your monitor in its fixed position for hours can result in strained neck and eyes. Reduce neck and eye strain as well as avoid poor posture and shoulder pain with a monitor arm, which allows you to easily adjust the angle, depth, and height of your monitor to ensure you're in your most comfortable, pain-free position for hours.
Avoid back pain with an ergonomic swivel office chair
Ergonomic chairs are the most popular ergonomic products on the market, and they really do make a difference to your wellbeing and health. If you're going to sit for a long time, you might as well get comfortable. Besides properly supporting your back and relieving you off from muscle fatigue and lower back pain, an ergonomic chair improves your concentration by limiting discomfort and allows for proper circulation.
Sit or stand while you work with an adjustable sit or stand desk
If you've got some extra space in your home office, consider investing in an adjustable sit or stand desk. Such desks allow you to conveniently adjust the height of your desk so you can work standing up or sitting down, whatever makes you comfortable. There's a study by Mayo Clinic which found that you can burn an additional 340 calories a day if you spend two hours standing up while at work, so alternate between sitting and standing whenever you can.
Type comfortably with an ergonomic keyboard
An ergonomic keyboard helps to minimise muscle strain, reduce the risk of carpal tunnel syndrome, and prevent other repetitive strain injuries. There are at least four types of ergonomic keyboards most commonly found on the market: the split keyboard, contoured keyboard, handheld keyboard, and angled split keyboard. Each of these keyboards has different key features that could benefit different people.


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Our Products
On BoardGameRags.com we offer several products which include two different types of unisex shirts, a unisex hoodie and girlies. Usually a so called "design" will be featured on all product types, this means a design like the "Karnivore Koala - Bearzerker" will be available as a black shirt and feature "Black Rag" in its title, as a second shirt in different color variants, as a hoodie and as a girlie.The colors available for a product heavily depend on the design itself. We will only feature colors that we think fit a design. That's why not all colors are always available for each design. Sometimes specific designs will indeed only be available on black shirts while others will not be featured on black products at all.
To better understand our products, here´s a list of our internal guidelines and the way we handle products:
The Black Rag Line will contain your designs on black colored shirts:
- 1 Shirt for $19.95
This shirt is a GILDAN 64000 UNISEX SOFTSTYLE which will be available in sizes S-3XL.
1 Girlie for $21.95
This shirt is an ANVIL 880 LADIES RINGSPUN FASHION FIT which will be available in sizes S-2XL.
1 Hoodie for $39.95
The hoodie is a GILDAN 18500 UNISEX HEAVY BLEND which will be available in sizes S-5XL.
The Color Rag Line is for all the designs on colored shirts. The available shirt colors will be chosen by us based on our experience but you can always tell us if there are specific colors you do or do not want:
1 Shirt for $21.95
This shirt is a BELLA + CANVAS 3001 UNISEX SHORT SLEEVE which will be available in sizes XS-4XL. This shirt is available in over 30 colors.
1 Girlie for $21.95
This shirt is an ANVIL 880 LADIES RINGSPUN FASHION FIT which will be available in sizes S-2XL. It comes in 8 different colors and we will make your design available in the best options.
1 Hoodie for $39.95
The hoodie is a GILDAN 18500 UNISEX HEAVY BLEND which will be available in sizes S-5XL. It is available in 8 different colors.
We want to provide top quality products and the chosen shirts and hoodies have proven to be great! They are exactly what we wished for as they are softer and not as stiff as regular shirts but still provide a high quality textile. Another important point is that they are "true to size", meaning that you should not experience any sizing issues as long as you go for your regular worn size. To make sure your size fits you perfectly, we still recommend you check the size charts that are listed on each product detail page.
All our products are "print on demand". This means they are only produced when ordered. The technique used for our products is called "DTG - Direct To Garment". It has a much softer feel to it than regular screen printing, but still allows bright colors and high details. We are totally convinced of this technique and we are sure you will love it too!

subset: commoncrawl


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Dental Implants
Dental Implant consists of a titanium screw (resembling a tooth root ) that offers better tensile strength and fracture resistance . Dental implants are artificial tooth roots used to support a restoration for a missing tooth or teeth, helping to stop or prevent jaw bone loss. The implantation procedure is categorized as a form of prosthetic (artificial replacement) dentistry, but also is considered a form of cosmetic dentistry.
Endodontics is the treatment of the diseased or infected dental pulp, which is the soft inner tissue of a tooth. The word "endodontic" comes from the Greek "endo" ,meaning inside and "odont" meaning tooth. Many teeth can be especially difficult to diagnose and treat. The complexity of anatomy or the bacterial infection often create a case which is beyond the skill level and experience of a general dentist.
Porcelain fused to zirconia (PFZ))dental restorations are made of safe, biocompatible materials. They have an extremely high flexural and tensile strength, and the non-porous design is resistant to chipping, cracking, and staining. The restorations have a smooth exterior, which prevents abrasion to surrounding teeth and gum tissue. In addition, zirconia is multicolored, highly translucent, and natural looking; our technicians use custom coloring techniques for seamless integration into your smile.
Orthodontics is that specific area of dental practice that has as its responsibility the study and supervision of the growth and the development of the dentition and its related anatomical structures from birth to dental maturity , including all preventive and corrective procedures of dental irregularities requiring and repositioning of teeth by functional or mechanical means to establish normal occlusion and pleasing facial contours .
Crown lengthening
Dental bridges
Dental bridges are one of several options that are used to replaced a missing tooth.
They provide the structure needed to keep other teeth from moving out of place and to keep your face shape the same as it has been.
Unlike other options Iike partials , a bridge is designed to restore your bite in a way that distributes tooth pressure .
Bonding /white fillings
Periodontics is the dental specialty focusing exclusively in the inflammatory disease that destroys the gums and other supporting structures around the teeth.
Our mouths are full of bacteria. These bacteria, along with mucus and other particles, constantly form a sticky, colorless "plaque" on teeth. Brushing and flossing help get rid of plaque. Plaque that is not removed can harden and form "tartar" that brushing doesn't clean. Only a professional cleaning by a dentist or dental hygienist can remove tartar.
Oral and cosmetic surgery
It's just about any surgery or cosmetic procedure to correct just about any kind of problem with the mouth, jaws. When you hear the words "oral surgery," you may think of a hospital setting, general anaesthesia, and one or more days in recovery from this type of dental procedure Because of that, you might be surprised to learn what is actually considered oral surgery in dentistry.
- Tooth Extractions
- Dental implants
- Bone graft
- Sinus lift
- White fillings
- Porcelain Crowns


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A play about self-worth, mental health and self-harm
Show Information
Tour Dates: 3rd June 2019 - 19th July 2019
Recommended Year Group: 8+
Running Time: 80 minutes
More Information
A play about self-worth, mental health and self harm..
When Sophia, Matt and Tash meet at a music festival they are three very different teenagers. They go to different schools, have different friendship groups and have led very different lives. However, they all have the same problem - they use self harm as a way to cope with their feelings. Sophia feels stifled by boarding school life, has a poor body image and feels out of control. Matt is consumed with anxiety about his impending GCSE exams. Tash is haunted by memories of a traumatic childhood and feels like the world would be a better place without her. When her only friend suddenly disappears. her self harming behaviour gets out of control. Hidden tells the story of the recovery of three very different teenagers as they struggle with mental health problems and self harming behaviour.
According to the World Health Organisation (WHO) there has been a threefold increase in the number of young people who self harm in the UK. With up to one in five 15-year-olds saying they self-harm and the NHS reporting a rise of 30% in the number of children (between 10 and 14) being treated by the NHS as a result of self harm, it is not surprising that local teachers surveyed have requested that Peer Productions tackle this challenging issue. This play, for year 8+ has been developed in consultation with clinicians, those who have recovered from self-harm and leading charities in the field.
This play will:
- Explain what self-harm is and what can trigger people to self-harm.
- Debunk some of the unhelpful myths surrounding self-harm.
- Enable people to find alternative and healthier ways to manage their emotions.
- Enable people to be a good friend to someone they suspect is harming themselves.
- Enable people to get help if they or someone they know is self-harming.


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Mainstage Theatre, 216 Union Street, Seattle
Sundae + Mr. Goessl will be releasing their 6th studio album, "Fun & Fancy", with a limited edition vinyl run at Seattle's most intimate live music venue, The Triple Door. Hosted by big-wig burlesque producer, Jasper McCann, this show will bring out both the Fun and the Fancy side of music and life with help from hip vintage trio Sweet Spot Combo and internationally acclaimed violinist, Andrew Joslyn.
$25 Advance // $30 Day of Show $35 Premium Seating and VIP // $40 Day of Show - includes a signed copy of the CD


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Cover your back
In every match there will be moments when the team us under a lot of aerial pressure. Defenders must be organised and put up a united front. Successful teams are often the most organised defensively. MORE
When faced with the threat of the long ball, your defenders need to be well drilled to cope and your attackers need to press high to deal with the danger at source.
The long ball, or ball over the top, is spoken of in derisive terms today – a stick used to beat teams for lack of subtlety and variation.
At grassroots level it is more common and where coaches have less time to coach their back four it can be a real thorn. It takes discipline, organisation and concentration to counter the threat of the long ball – but with your back four well drilled, the tactic rapidly loses its effect.
The solution to countering the long ball begins with your own attackers and this is the theme of the first drill. Most long balls are launched from deep, bypassing the midfield completely, and your forward line must be reminded they have a defensive role, too.
Your forwards need to close down those missiles and stop them at source. This means engaging high up the pitch, getting on top of opponents before they can size up a target, and then force them to lay the ball off, charge it down, or best of all dispossess the player. Dropping off deep only encourages those balls to be aimed with more and more precision from closer and closer to your six-yard box. There, one touch, or even a deflection, can result in a goal.
Your defenders must concentrate hard and read the game, playing on the half-turn and not losing sight of runners off their shoulder. A disciplined defence will also work hard to keep a tight line and play the offside. Former Arsenal manager Arsene Wenger maintains "the long pass is predictable, you have to be mentally strong enough and technically coordinated to play them offside".
If the opposition are still able to launch the ball into your penalty area, your team need to drop a little deeper and work as a unit as the second drill demonstrates. One player, the best aerial defender, needs to challenge the striker, with the rest ready to pounce on the second ball if it drops in a danger zone.
With the two sessions below your teams will soon be coping with the long ball.
Long balls are difficult to defend against unless you get your players following these handy tips…
> Attackers should press high up the pitch to put pressure on players looking to launch the ball long
> Organise the centre of defence to clear aerial attacks
> Force opposition wingers inside to stop them crossing the ball
> Fullbacks and wingers should double up on wide players
> The midfield should battle hard to prevent flick-ons


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Build an integrated MarTech strategy that aligns with your business growth
Is too much technology overwhelming you? Modern marketers use anywhere between ten to twenty tools to conduct the strategic marketing activities in the offline world, the social media and the digital space. Managing all these applications and making them work coherently is one of the biggest challenges faced by marketers.
Out of the hundreds of marketing tools available, it becomes a challenge to select the right one. Having worked with all popular marketing technologies, we guide you with the pros and cons of each tool and how it could impact your bottom-line.
Implementing multiple marketing tools and making them work in-sync with your current business practices is what we do best. We ensure that your implementations are scalable so that they support your business growth flexibly.
We optimize, update and customize the marketing tools based on your dynamic business requirements so that you achieve the best possible results from your marketing technology stack.
We study your current marketing technologies and identify the gaps, areas of automation, implementation feasibility, and need for additional solutions to meet your business requirements.
We take the complete responsibility of implementing and integrating the new and existing marketing tools so that you get a seamless and high-performing marketing stack.
The marketing world is constantly changing and we help you to smartly customize and optimize your mar-tech stack.
Get the maximum results out of your mar-tech investments.
We help you get the best out of your investment in tools for website management, social media management, marketing automation, email marketing, e-commerce, audience targeting, web analytics, personalization, content management, CRM, and more.


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Today on the Don Geronimo Show…
Little Joe shares with us his NEW workout plan.
Don wishes we could sacrifice Pitbull to Mother Nature.
Don and Joe discuss the FBI arrest of WFAN DJ, Craig Carton.
Little Joe tells Don this years Dancing With The Stars cast.
The boys discover how exactly the Red Sox used their Apple Watches to steal signs from the Yankees.
Don and Joe ask which celebrities would be better than President Trump.
Don plays a FOX anchor breaking down as she defends President Trump.
Don shares with us his Fantasy Football team.
The boys had a phone scan before Don got to his random news including a mother sharing her breast milk with Hurricane Harvey victims.
And they closed the show with "What Does The Fox Say".


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Automated Shooting Range for Air Pistols
Alternative metrics PlumXhttp://hdl.handle.net/11012/42919
MetadataShow full item record
This work deals with the design and manufacture of the device, which is used as a shooting range to practice shooting with an air gun. The device is controlled by the Arduino MEGA and could be connect to any number of smart targets. It is designed to be easily portable, comfortable to use, to enable multiple modes of activity and support several of shooters. The secondary aim is also to ensure the attractiveness of the firing for shooters.
Persistent identifierhttp://hdl.handle.net/11012/42919
Document typePeer reviewed
Document versionFinal PDF
SourceProceedings of the 21st Conference STUDENT EEICT 2015. s. 23-25. ISBN 978-80-214-5148-3
- Student EEICT 2015 [169]


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The 12 Inch Seasoned Cast Iron Everyday Pan features sloped sides for sautéing and stir frying. This 12 inch tempered glass lid is light weight and allows for peeking without losing moisture and flavor.
Type: Pans
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© 2020 LifestylesCo Inc.


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Clients, companies or individuals contemplating or currently engaged in litigation will inevitably see reference and correspondence in relation to 'ADR'. It is not uncommon for our litigators to take enquiries from clients and potential clients to determine what is meant by the phrase ADR and how it affects them.
ADR (otherwise known as Alternative Dispute Resolution) refers to a series of mechanisms and techniques that seek to draw the parties of a dispute or potential dispute to a conclusion, without the need for Court proceedings, or if in Court proceedings when ADR is undertaken, without the need for further proceedings and possibly a trial. The purpose of ADR is to circumvent the cost, complexity and stress that can be associated with issued Court proceedings, to relieve the burden upon both the litigants themselves and the Court. Since the inception of the Civil Procedure Rules in 2001 ADR has become more prevalent, and continues to be so year on year.
Indeed, when Judges make decisions as to how claims ought to progress, they consider information set out by the parties in a directions questionnaire. Over the last couple of years we have seen the Directions Questionnaire change to incorporate a section requesting a stay or pause in proceedings whilst ADR is undertaken and the instructed solicitor must confirm to the Court he has explained the consequences of failing to deal with ADR to his client. Mediation is now seen as part of the litigation process when 10 years ago it was perhaps a rarity if considered at all.
At Edward Hands and Lewis we embrace Alternative Dispute Resolution as a mechanism of achieving our client's goals without incurring the expense ordinarily associated with civil proceedings. We have a number of litigators with a host of experience in ADR techniques and attend without prejudice meetings, mediation and employ ADR techniques from the Civil Procedure Rules on each matter we are instructed upon. Where ADR fails the practice remains geared up to pursue litigation in the Court forum with vigour but peace of mind is given to clients that if litigation ensues it is as a result of the personality of the parties rather than any failure to attempt to draw the matter to a conclusion as cost efficiently as possible.
If you wish to explore ADR please do not hesitate to contact Paul Stubbs on 0116 266 5394 or firstname.lastname@example.com to our legal team
The information provided in all of our blogs reflects only a narrative of some elements to consider on the topic. The blogs do not contain considered legal advice and should not be relied upon as advice. Please see our website terms and conditions for full details of our disclaimer. If you are interested in obtaining advice, please contact one of our lawyers who will be happy and able to advise you on your own particular circumstances.


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Honour. Glory. Paperwork.
Greetings, Guardsmen. A solemn duty now falls to you. Recently, your war zone was blessed with the timely intervention of the White Scars and Ultramarines. To see one Space Marine […]
Greetings, Guardsmen.
A solemn duty now falls to you.
Recently, your war zone was blessed with the timely intervention of the White Scars and Ultramarines. To see one Space Marine Chapter of the most holy First Founding in battle is a privilege few Guardsmen can aspire to ? to witness two working in tandem is the stuff of legends.
However, once the foe is vanquished, a final trial remains ? a task that not even the Adeptus Astartes can shoulder.
Presumably, in their hurry to go do more good deeds, the White Scars have failed to complete their forms ? namely Permission To Intercede In An Astra Militarum War Zone, Permission To Save The Lives Of Guardsmen From A Perfectly Good Martyrdom and Invoice For Shots Fired, Materials Destroyed And Good Decorum Broken.*
That is where you, humble Guardsmen, come in. To reward you for your nobility in combat, we have decided to give you the forms to complete on their behalf, thus allowing you to experience the thrills of life as a Space Marine for yourself. Just imagine the adrenaline-pumping euphoria from working out the exact value of a particularly impressive grain silo obstinate enough to obstruct the glorious advance of an Invictor Tactical Warsuit. Success here is an opportunity to prove your valour ? just imagine the stories you?ll be able to tell your grandchildren!
Due to the hasty departure of the White Scars, some paperwork may require a small amount of reassembly, but we have no doubt you are up to the task. Good luck!
++ Thought For The Day: We do not flinch from death. ++
* You will be disappointed to hear that the Ultramarines have filled in all their paperwork in triplicate, exactly according to Adeptus Munitorum scriptures, including several volumes of ordinances and regulations thought lost for several millennia.
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A Hidden Life
Book 1 - The Watchers Trilogy
England, 1560 - The mysterious fate of Amy Dudley threatens to ignite a rebellion that could destroy Elizabethan England.
Sir Samuel Banks, a former royal spy and death doctor, is put in charge of the investigation. But as Sam unravels the secrets surrounding Amy Dudley, he uncovers a sinister plot and more people die.
Can Sam discover the truth about Amy Dudley before it's too late to save queen and country?


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Golfing Over It with Alva Majo, PC Download, For PC
It is Full and Complete Game 100% Working.
Golfing Over It with Alva Majo is an action video game developed and published by Majorariatto.It was released on 28 Mar, 2018 for PC.Golfing Over It with Alva Majo is a discouraging game about climbing a surreal mountain with a golf ball, a different take on 2017's hit Getting Over It with Bennett Foddy. Experience the challenge of climbing an unyielding mountain without infuriating controls being part of that challenge.we provided Golfing Over It with Alva Majo PC Game with pro account of mediafire(without ads, direct link) under 100 MB.Is this game is free and for Pc? Yes this game is free video game and for Computer. Please see below screenshots and system requirements to understand you, Can you able to play this game on pc? so after check out download , Install, play and Enjoy!.Now Check Out Below Download link ,download game and enjoy!.According to me Download >>Install>>Play>>Enjoy!.
Golfing Over It With Alva Majo FREE Download Full Version
System Requirements of Golfing Over It With Alva Majo
Check given below minimum system requirements of Golfing Over It with Alva Majo PC Game.
- OS: Microsoft Windows XP/vista/7/8
- CPU:Intel Centrino 2
- Video Card: ATI Radeon HD 4850
- HDD:200 MB Free Disk Space
How to Download and Install Golfing Over It With Alva Majo For PC?Most important question is how to download this game from my website? You can download this game in following steps.
- First Download Golfing Over It with Alva Majo by click on download link.
- Unzip File Using "Winrar".
- Open "Golfing Over It with Alva Majo.CheckGamingZone" >>> "Game" Folder.
- Then double click on "Golfing Over It with Alva Majo" icon to play the game.
Need Help!:If everyone have problem in downloading or in installation then leave a comment.Kindly comment is related with this post.
Check Gaming Zone is a blog, which was created in 2013 and is known for having a large collection of PC Games.Where you can download most popular PC Games in Highly compressed mode.We are providing games with high server mediafire link (without ads, direct link) and also torrent link games.
Winrar Password: checkgamingzone / checkgamingzone.blogspot.com
File size:84 MB


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10 Creative Ways to use Mod Podge
Sometimes living a life with standard objects gets boring. You might be laying on the couch watching a Netflix marathon on TV or trying to study for … Read More
Sometimes living a life with standard objects gets boring. You might be laying on the couch watching a Netflix marathon on TV or trying to study for … Read More
Sometimes a girl needs a new pair of shoes, but sometimes that girl already has too many shoes. In this case, making over a pair of shoes may be the … Read More
A missing puzzle piece means certain disaster! A puzzle will never be the same with even one missing piece. What is a person to do with all of those pieces? … Read More
Many of us would love to make fun crafts for our children or as gifts, but must require sewing. Since sewing is not an option for many people, the … Read More
Glitter is a great way to add sparkle to your life. It is impossible to have a bad day with the added sparkle of glitter. Though it has been … Read More
Life comes with chores, but that doesn't mean it has to be miserable. Laundry rooms can be overwhelming and one of the last places one might think to organize. These … Read More
Tis the season for crafting. Peppermints and candy canes are iconic symbols of Christmas. I've found so many great ideas for using the red and white {or green and white} … Read More
Free Printables are popular in the blogging world, but I've encountered a lot of people who don't understand how to use them. I've scoured the internet and found some great … Read More
People love free stuff. Most people love Christmas. I love both so here are some free Christmas printables I created (so they are one-of-a-kind printables) for everyone to use. I … Read More
Sometimes Santa needs a little Christmas help filling up all those stockings. These ideas are sure to delight most any person on your Christmas list. Walnut Jewelry Box Found on … Read More


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3D Hero Super Spider Rider app
3D Hero Super Spider Rider is an amazing free superhero fast speed motor bike racing game. The strange spider mutant superhero legend is known for its strange supernatural super powers and is ready to hit the road to take down the bad guys. Fire missiles, use NOs, or simply destroy on coming traffic and targets to come out victorious. Drift your super fast sports motor bike in this fast paced moto racing game with a twist of 3D hero game as well. Being last hope of humanity spider super hero legend has always served this metropolis city in the dark nights with its mutant powers. Amazing super spider legend has always played his role on catching the bad guys, fighting the super villains, monsters and criminals who have tried to destroy the peace of the metropolis city. The amazing spider 3D hero has proved himself a true hero ranger. Ride on your iron bat ride to take on the most dangerous villains and monsters in the moto racing race. Race your rival racers and dominate everyone throughout the metropolis city as a superfast amazing spider hero, just when police city block isn't an option anymore.
Drive like a bullet, ride on the roads of the most beautiful city and beat your super power opponents in this amazing motor bike racing game. The only goal of mutant super hero legend is to race throughout the city prevail over the super villains. It's a battle of strange superheroes. It's a combat of super powers. Show your super power racing skills. Drive like no one can. Show some stunts that no one has courage to do. When you are on your super-fast motor racing bike the whole city is yours. Ride and race like a pro and dominate the city and show your abilities because the heroes never die. Use your super powers to assualt enemy soldiers, and take the villains out of the race or ride like a fastest man alive with rope, chains and sticks. Hit your rivals with stick, rope or change if you or play clean if you want to have a clean ride and race. With amazing turns on the road and busy highway will make this hero battle difficult and this game wild. In the world of climbing wall, spider super hero league ranger is here to show justice and amazing bike stunts.
Features of 3D Hero Super Spider Rider:
Immersive 3D Racing and Bike Stunt Environment
Unique Powers to destroy on-coming traffic and enemies
Realistic Racing Game 3D Sound Effects
Amazing game physics
Plenty of levels to complete
Bat and chain with strange super powers to make game more interesting
Similar Apps


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The Request for Proposal process (RFP) is like a buffet. You can't help but want to try everything and anything, knowing full well that by doing so it will make you sick. Or in this case, broke.
As I wrote in Are RFPs Bad for Business? Part one, I find RFPs to be an exasperating and costly endeavour for firms. Beyond Referrals uses the real-life example of having 38 vendors each spending $20,000 to write a proposal, totalling an industry response cost of $760,000 just to bid on one RFP—for which the winner would receive $50,000 in fees. This means 15 times more money was spent by the industry writing proposals than the winner would get in fees. That's a huge amount of money and a huge drain on the economy when you consider how many "upside-down" RFPs are issued every year in Canada.
Furthermore, what makes this process even crueller—and is perhaps my biggest criticism directed towards the RFP process—is how much value some RFPs place on price in the evaluation criterion.
For example, in a score out of 100, an RFP will often value price at 50 points, which is half of the entire proposal! So, if you haven't competitively priced your fee or if you haven't received full marks on your qualifications, you've lost the proposal.
I find the entire grading systems to be counter-intuitive to celebrating and creating innovative design and moving towards building more resilient and sustainable infrastructure.
Luckily, many government and procurement entities are helping to rectify this aspect of the bidding and tendering process by implementing new practices such as Request for Qualifications (RFQ) and Qualification Based Selection (QBS).
RFQs separate qualifications and price by judging proposals first on qualifications and limiting submissions to a few top firms who achieved enough points to move forward. Price is finally entered into the equation at the end instead of being a determining factor from the beginning.
QBS excludes price as an evaluation criterion altogether when hiring a professional service firm for a project, improving the ethicality, transparency, sustainability and quality of a selection process. Already required by law when procuring architecture and engineering services for federal and state projects in the United States, QBS gives consultants the opportunity to prove why they are the best choice for a project, instead of bidding the lowest in order to win.
Yet, until RFQs and QBS are fully implemented in the bidding and tendering process, we must find or create our own RFP buffers to save money and better utilize our productivity and time.
From experience, I know that not all RFPs are created equally. Sometimes an RFP will ask for free work (which is never appropriate) and other times it will lack pertinent information such as the budget, a defined scope of work or even a defined list of services.
You can always email the project coordinator or the RFP contact, but it doesn't mean that they can or will give you the answer(s) you're looking for. So, what kind of system can you implement in your firm to make executive decisions on whether or not it's logistically possible to pursue the RFP?
At Nadi, how we decide to pursue an RFP relies solely on the Go vs. No Go process, which was inspired by Beyond Referrals similar selection process, but with a few more tailored questions related to our firm. The Go vs. No Go is a sobering, but necessary set of questions to rationalize our desire to chase an RFP. Because as much as I complain about RFPs, I tend to get excited (and blinded) when I come across one that appeals to me or the firm's goals—even if it's impossible for us to win it.
The Go vs. No Go system separates emotions (like excitement) from the reality of submitting and winning the proposal. Questions such as: Is not responding a realistic option? Can we do the work? And, Do we want the work? Helps us review the RFP without becoming emotionally invested and caught up in the "what ifs" associated with it. It's hard to blindly chase an RFP when the evidence shows that you won't be competitive or successful.
Since we implemented this process, we have become more sophisticated in which RFPs we choose to pursue and how we approach them. We do research on the project and on our competitors, sizing ourselves up not only on qualifications but how pricing, like outsourcing sub-consultants, will look stacked up against firms or agencies that don't have to account for extra fees. If you can't be competitive, at least be smart, right?
Until the bidding and tendering process evolves, I highly recommend creating your own Go vs. No Go process to streamline how your firm or agency pursues RFPs. We waste millions of dollars pursuing RFPs that we won't or can't win. By understanding this process and implementing one of your own, you can work smarter, not harder—and become a more competitive buyer in the process.


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America: Australia's Dangerous AllyRoundup
tags: Australia
It is time for Australia to end its strategic dependence on the United States. The relationship with America, which has long been regarded as beneficial, has now become dangerous to Australia's future. We have effectively ceded to America the ability to decide when Australia goes to war. Even if America were the most perfect and benign power, this posture would still be incompatible with the integrity of Australia as a sovereign nation. It entails not simply deference but submission to Washington, an intolerable state of affairs for a country whose power and prosperity are increasing and whose national interests dictate that it enjoy amicable, not hostile, relations with its neighbors, including China.
As painful as a reassessment of relations may be for intellectual and policy elites, there are four principal reasons why one is long overdue. First, despite much blather about a supposed unanimity of national purpose, the truth is that the United States and Australia have substantially different values systems. The idea of American exceptionalism is contrary to Australia's sense of egalitarianism. Second, we have seen the United States act in an arbitrary, imprudent and capricious fashion. It has made a number of ill-advised and ill-informed decisions concerning Eastern Europe, Russia and the Middle East. Third, at the moment, because of U.S. military installations in Australia, if America goes to war in the Pacific, it will take us to war as well—without an independent decision by Australia. Finally, under current circumstances, in any major contest in the Pacific, our relationship with America would make us a strategic target for America's enemies. It is not in Australia's interest to be in that position.
American fecklessness has produced this state of affairs. As the recent twenty-fifth anniversary of the fall of the Berlin Wall reminds us, the breakup of the Soviet Union created a different world. It was a world bursting with opportunity, as was first described by President George H. W. Bush in a speech to Congress after the first Gulf War. Bush was then talking about a new world, one in which there would be much greater cooperation between nations large and small. It was the kind of speech that many people worldwide wanted to hear from an American president. However, the purposes and commitment expressed in that speech were to be cut short. The presidents that followed—Bill Clinton, George W. Bush and Barack Obama—may have differed in tone but not in substance. They have all adhered to the illusion of American omnipotence.
It was Morton Abramowitz of the Carnegie Endowment for International Peace, a former U.S. ambassador and one of the prime movers in establishing the International Crisis Group, who wrote in 2012 that "American exceptionalism dooms U.S. foreign policy." Nothing has altered since then. Even President Obama has embraced the idea of exceptionalism, telling the UN General Assembly in 2013, "I believe America is exceptional." A nation better than any other, innately motivated to do good; what America does is right because America does it. The idea of American exceptionalism, which has always been present in the United States, has gone far beyond all comprehension in the years of America's absolute supremacy. It has created a different nation, a different society. Such ideas influence American foreign policy in ways that make it much more difficult to achieve a secure and safe path in the future. Our task is not to embrace America, but to preserve ourselves from its reckless overreach...
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- Harry Reid on the Senate, the Supreme Court, and a Time for Major Change


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Merrie Melodies: Starring Bugs Bunny & Friends is a compilation show that first ran in syndication from 1990 to 1992, then moved to Fox Kids starting in 1992.[1] Each half-hour episode ran three classic Warner Bros. cartoons. In the syndicated version, some episodes included a "Hip Clip", which is a snippet from a classic WB cartoon (oftentimes, it was a scene that would usually be edited from a cartoon that was censored).
- ↑ "The Merrie Melodies: Starring Bugs Bunny and Friends Page
External links
Kevin McCorry's Merrie Melodies: Starring Bugs Bunny and Friends page
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Hima Necklace
This product is available.
Regular price
Two-tone long bar lariat pendant necklace showcasing a sleek, minimal style for everyday wear. Hand-forged with hammered details and contrasting beaded wire shapes the characteristics of the design.
- Pendant size: 2.75" L
- Chain length: 19"
- Available finishes:
- polished bar w/ charcoal dots + sterling silver chain
- gold-fill bar w/ polished silver dots + 14K gold-fill chain
- Handcrafted in recycled precious metals > sterling silver or 14K gold-fill
- Ready to Wear: Ships within 3 business days


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BBC News ethnic group has mocked Governor Rochas Okorocha for building a President Muhammadu Buhari-like sculpture in Owerri, in Omo State.
Sharing the photos on its Facebook page, the news medium questioned if the governor was ne'er uninterested in building statues.
BBC wrote in ethnic group, "It's like Okorocha isn't uninterested in building statues, UN agency is he building for United Nations agency folks again?"
Rochas Okorocha wasn't issued a Certificate of come by the freelance National Electoral Commission, INEC, on Th, when he was adjudged to own forced the functionary for United Nations agency West legislator District to declare him the winner of the February. twenty three legislator election.


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With 20 years of experience, Jessica Richardson specializes in providing highly personalized service to buyers, sellers, and investors. Her industry success and proven track-record have made her one of the most sought-after Realtors in the DC Metropolitan area. Jessica's business philosophy is based on honesty, integrity and market knowledge. These principles, along with being an excellent negotiator and communicator, have resulted in hundreds of closed sales. Having experienced the market's highs and lows Jessica has the knowledge and expertise to navigate through even the most difficult of transactions.
The daughter of a second-generation Washingtonian, Jessica has lived in the DC area most of her life. She is consistently ranked among the top Realtors in the DC Metro area. She is an NVAR Life Member, Top Producer and has been named a Top Realtor by Washingtonian Magazine and one of American's Best Real estate Agents by the Wall Street Journal and REAL Trends. Jessica lives in Alexandria with her husband and their two daughters. In her free time, she enjoys playing tennis, running and trying out new local restaurants with friends.
Whether you have a general question, you want to talk about how I can help you find your dream home, or you want to begin the conversation about how you can get your home sold faster than you think possible… you're in the right place.


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HJD-DP02 T shirt Digital Inkjet Printer
Parameters list
print method
TWO Epson 5113 or DX5
Operation system
output Size
Input Power
AC 220V 50 Hz 1000W
Ink colors
(4 colors)
Outline Size
6000mm*3350mm*1100mm (L*W*H)
Ink type
Acidity , reactive, disperse,coating ink all compatility
standard USB
working environment
temperature:15-30oC, Relative humidity: 40-60%(non-condensing)
RIP software
wasatch , maintop
output resolution
colors adjusing software
Ai, Photoshop
printing speed
4 pass 90-110 pcs/hour
HJD-DP02 product show:
HJD-DP02 product details:
1. The printing is fast , especially for sample printing ;
2. The production cost is low, it doesn't need the edition of silk screen frame , because it can print any pattern direct on garment;
3. As for the deep colors garment printer printing , the white silk screen printing bottom and colors printer printing . The printing cost is saved lots and printing capacity will be enhanced;
4. The Y-axis adopts rack and rail transmission system, and the printing precision is higher and more stable;
5. The length of the whole machine can be infinitely extended,add 1.5 meters per section;
6. The frame adopts one piece of welding, CNC whole processing, the structure is stable, the precision is high;
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8. It is widely used in ready-to-wear, clothing, cloth, etc;
9. Optional drying module .
All items of our products and related tests as follow :
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I'm a composer still in the research phase of using samplers and sample libraries. I'm quite familiar with most other aspects of digital audio recording and manipulation (good old college education and lots of practice), but I'm finding my current setup lacking: for orchestral works, I write everything in Sibelius, export the MIDI file to Sonar, and record the sounds straight from my synth's patches.
As you can imagine, this setup is quite lacking in that the patches, while very good, are nowhere near as good as the biggie sample libraries. And the only articulations I can control are the basic ones I do with MIDI, whether in Sibelius or Sonar. I've been researching the realtime editing options that libraries like GPO offer, and I'm excited about what's possible.
My question is, with samplers like Giga or Kontakt, is there a way to see the results of manipulating articulations? Do these programs allow for graphic editing of articulations? In other words, let's say this: I have a solo violin part. I load the raw MIDI file with nothing but note-on messages into Kontakt. Can I use the editing functions unique to Kontakt to edit dynamics, legato phrasing, and different articulations graphically like I use the normal piano-roll graphic to do basic MIDI editing?
Sorry for the long question, but it's hard to get across what I'm confused about. Thanks in advance for your replies, or if you can point me toward any web tutorials or previous threads on this that would also be of great help.


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HVCA Neighborhood Party
Hemingway Village Civic Association plans one large neighborhood party each year. This is a time to try and get all the families together
before winter drives us indoors and we loose touch for a while.
2016 HVCA will hold a back to school party on Saturday Sept 10th from 12pm -5pm
Stonefield Park
More details will be coming.


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Kamado Joe, the innovative manufacturer disrupting the ceramic grill category, announces the launch of two new kamado-style grills: the Classic III and Big Joe III.
The much-anticipated III Series grills are the first to feature the company's breakthrough hyperbolic smoke chamber, dubbed the 'SlōRoller.' The innovative chamber was developed by a team of Harvard researchers, and maximizes smoke flavor and heat distribution by changing internal pressure to create optimal cyclonic airflow inside the grill.
The new Classic III (MSRP: $1,599USD) and Big Joe III (MSRP: $2,399USD) will be available at retail partners across the globe.
"We are continuously challenging ourselves to build the best grill ever made. The III Series is no exception. We used the best materials, world-renowned science, and top global partners to deliver grillers a ceramic style grill that outperforms anything on the market," explains Bobby Brennan, CEO of Kamado Joe. "It's not just new — it's scientifically better."
The SlōRoller Hyperbolic Smoke Chamber
Built with technology never before used in the grilling industry, the SlōRoller leverages patented science developed by Desora, a team of Harvard researchers that set out to transform a kamado-style grill into one of the world's most optimal smokers.
The SlōRoller's hyperbolic technology fundamentally changes the airflow pattern inside the grill, causing smoke to revolve around food five to 20 times more than other grills. By distributing smoke and heat in rolling, recirculating waves, the SlōRoller surrounds food in smoke while evenly distributing heat, resulting in enhanced flavor and up to an 80 percent reduction in hot spots.
New Series Incorporates Numerous Innovations
As with their predecessors, the Classic III and Big Joe III grills also feature a thick-walled, heat-resistant shell that locks in smoke and moisture at any temperature. The easy-open top domes include the counterbalanced Air Lift Hinge and element-proof, ultra-precise Kontrol Tower top vent. While the large cooking surface underneath is crafted from commercial-grade 304 stainless steel.
The III Series grills also come standard with the three-tier Divide & Conquer® Flexible Cooking System with Charcoal Basket, the Advanced Multi-Panel FireBox, heat resistant powder coated aluminum side shelves, a heavy-duty rolling galvanized steel cart, and a patented slide-out ash drawer for easy cleaning.
In addition to the new grill series, Kamado Joe is also adding to its range of pro-grade grilling accessories. The wedge-shaped DōJoe pizza insert, which converts the Kamado Joe Classic or Big Joe grill into a high-performance pizza oven, creates an optimal environment for perfect crust and crisp toppings.
Kamado Joe Launches New Grills and Unveils Innovative New 'Smoke Chamber
To learn more about the technology and design behind the SlōRoller, as well as Kamado Joe's latest additions to its product lineup, visit kamadojoe.com.


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Did you ever go there?
Express your EcoOpinion about this place and become a GreenWatcher, the trend setter of Sustainability.
The EcoOpinion is based on the algorithm of The GreenWatcher which is used to express the value of ecosustainability that you see with a score from 0 to 5.
- 13 January 2015JessicaCastiglioneMilano
vendita e produzione di vestiti con materiali naturali. ambiente curato con riuso di arredi2.4
Is this your company?
Whit just a few clicks you can... EcoAssess it and certify your level of Eco sustainability!


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Lydia Koniordou, Greek Minister of Culture and Sports, said at the Onassis Cultural Center for the exhibition A WORLD OF EMOTIONS:
"Μ?νιν ?ειδε, θεά, Πηληϊάδεω ?χιλ?ος ο?λομένην, ? μυρί? ?χαιο?ς ?λγε? ?θηκε, πολλ?ς δ? ?φθίμους ψυχ?ς ?ϊδι προ?αψεν ?ρώων,
Sing, Goddess, Achilles' rage,
Black and murderous, that cost the Greeks
Incalculable pain, pitched countless souls
Of heroes into Hades' dark
These are the opening lines of the Homeric epic of the Iliad, «Μήνις», rage is the theme that connects and runs through all rhapsodies. However it goes on immediately to point out the destruction, pain, and death it results, to fine men and heroes.
The rage of Medea by Euripides, the «ολετήρας θυμός», the "destructive rage" that wipes out the prosperous city of Corinth…
I will speak not as a scholar but as a servant of the Arts for many years, especially of Greek drama.
Ancient Greek tragic poets, bearing the spirit of their times, philosophic, aesthetic, go to great extent to illustrate the real causes of extreme emotions, and their effects on people's lives, both private and public.
A major contribution of the Greeks to our western civilization was the introduction of dialogue as the foundation of the newly-born Democracy and its institutions, theatre being one of them.
For example, Emotions in Greek tragedy are indications, resulting from inner and external dialogue, dilemma or conflict, opposing ideas, goals, ambitions, as opposed to fear of punishment from loss of «Μέτρον» (Balance).
They are depicted vividly, not as an aim per se, but to uncover a whole dialectic process of balancing Intellect, Heart and Necessity, through an endless game between Light and Shadow, Life and Death.
The realization, through Emotions of this process, and the price of each choice brings light of consciousness and promotes the maturity of the citizen.
I have been for decades inspired by the ideas and masterpieces of the ancient Greeks. When I look at these treasures, that capture Emotions through gestures, through dialogue in their body and structure, I cannot but feel a different kind of emotion as a contemporary visitor.
I cannot but feel the hands that gave form to this piece of marble, to that handful of clay, I sense the emotions emanating from the artists' feverish attempt to transform and transcend matter.
I cannot but sense all the eyes that had admired or worshiped these masterpieces in their own ancient times. All the hands that touched the objects of everyday life and were, often unconsciously, inspired by their beauty.
And yet again, I cannot but feel the deep emotions of all those generations of SIMPLE workers, farmers, divers, archeologists, restorators, that helped discover and restore all these treasures for us to admire today, to study and learn from.
These are precious Emotions from real people that are also projected on these treasures and give them life (see ευπαλινειο). Parallel lives that offer deep emotions to us contemporary visitors.
All this process of transcending matter through spirit, is to the glory of human civilization, it offers moments of immortality and wisdom all human beings can share.
Greek cultural heritage is a great gift that contemporary Greek citizens have the privilege and obligation to discover, restore, maintain and share with the world, as it is a fundamental part of our common world heritage
Despite the austerity measures and the major difficulties in our lives, our country handles with great responsibility this unique heritage. It is for us an endless source of inspiration for our present and future, against odds, to create, to contribute, to a bright artistic present we wish to share.
The Greek State, through the Hellenic Ministry of Culture and Sports, serves as the guardian of our cultural heritage. It wishes to assist every effort that seeks to illuminate the flame and beauty of this heritage, to citizens around the world.
In this endeavor we are not alone. The Onassis Foundation is one of the most significant contributors to this objective. Through a series of exhibitions and activities, the Onassis Foundation successfully brings together museums, academics and artists. This Greek institution, firmly and generously supports both the ancient as well as the contemporary Greek culture in Greece and abroad.
The Ministry of Culture could be no less than a fervent ally in this important initiative.
In this exhibition the Ministry of Culture Participates with masterpieces from 20 National Museums, both central and major, as well as regional, but equally important.
In the exhibition we can admire statues and reliefs of outstanding beauty that capture emotions on bodies and faces, stele, figurines,
_ from the breathtaking enigmatic Kore from the Acropolis museum, to the head of a smiling child from Vravrona museum
_from the statue of one of the Ptoon Kouroi, from the Athens Archeological Museum, to the head of the youth and the figure of the embracing couple from the Delos museum
_from the tablet of Clytemnestra killing Agamemnon, from the Heraklion Crete Museum, to the funerary stele of an actor holding a mask from the Piraeus museum…
I would like to congratulate the Onassis Foundation and all those who worked together for the realization of this exceptional exhibition. I wish every success in presenting and illuminating the element of Emotions from the ancient times to the contemporary visitors, here in NYC."


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- Cet évènement est passé
POSTPONED! Stayin' Alive – Personal and Team Approaches to Safety and Security
March 31 @ 9:00 am - 5:00 pm EDT
Please note the locations for each training:
- February 10 & 11: Toronto – The 519 (Directions) *Please also register for the Triannual Meeting
- March 16 & 17: Montreal – CECI (Directions) (In French) POSTPONED
- March 31 & April 1: Ottawa – CARE Canada (Directions) POSTPONED
*If there is insufficient registration, courses may be combined. We will attempt to accommodate the preferred date/location of the highest number of registrants.
Why it's important:Training staff to work together safely amidst risk is a fundamental component of an organization's duty of care to their staff. And highly trained and competent staff form the basis of quality humanitarian and development programming.
Who it's for:This two-day training workshop prepares NGO staff and volunteers to travel and work in low to moderate risk locations, equipping them with the skills and knowledge to understand the risks they may face, implement prevention measures, and react in ways that prioritize their survival and well-being and that of their teams. This training also provides a solid understanding of safety and security risk management approaches which prepares staff for more advanced courses such as Hostile Environment Awareness Training.
This is a classroom training which engages participants through games, case studies and other participatory activities.
Topics covered include:
- Personal Risk Tolerance
- Gender, Diversity and Risk
- Situational Awareness
- The Bystander Intervention Approach
- Community Acceptance
- Personal Preparedness
- Motor Vehicle Safety
- Theft
- Hotel Safety
- Political and Civil Unrest
- Terrorism
- Natural Disasters
- Kidnapping
- Stress and Resilience


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find out how to receive payment for your shares.
California's Transparency in Supply Chain Act of 2010
Rich Dudley
Sr. Director of Investor email@example.com
BATESVILLE, Ind., July 23, 2019 /PRNewswire/ -- Hillenbrand, Inc. (NYSE: HI) will hold a conference call and simultaneous webcast Thursday, August 1, 2019, at 8:00 a.m. ET. They will discuss the results for the third quarter of fiscal year 2019, which ended June 30, 2019. The live webcast, including a slide presentation, will be available at http://ir.hillenbrand.com under the "Events & Presentations" tab and will be archived on the company's investor relations website through Friday, August 30, 2019.
To access the conference call, listeners in the United States and Canada may dial +1 (833) 241-7251, and international callers may dial +1 (647) 689-4215. Please use conference call ID number 6642849. A replay of the call will be available until midnight ET, Thursday, August 15, 2019, by dialing +1 (800) 585-8367 toll free in the United States and Canada or +1 (416) 621-4642 internationally and using the conference ID number 6642849.
Hillenbrand will issue a press release reporting its results after the market closes on Wednesday, July 31, 2019. The full text of the release and financials will be available at http://ir.hillenbrand.com.
About HillenbrandHillenbrand (www.hillenbrand.com) is a global diversified industrial company with multiple leading brands that serve a wide variety of industries around the world. We pursue profitable growth and robust cash generation to drive increased value for our shareholders. Hillenbrand's portfolio is composed of two business segments: the Process Equipment Group and Batesville. The Process Equipment Group businesses design, develop, manufacture and service highly engineered industrial equipment around the world. Batesville is a recognized leader in the death care industry in North America. Hillenbrand is publicly traded on the NYSE under "HI".
View original content:http://www.prnewswire.com/news-releases/hillenbrand-schedules-third-quarter-2019-earnings-call-for-august-1-2019-300889755.html
SOURCE Hillenbrand, Inc.


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Chicken Avocado Burgers
Sunday, February 10, 2019 Edit
Prep Time: 10 mins
Cook Time: 15 mins
Total Time: 25 mins
A new twist on a Chicken Avocado Burger! Mix cubed avocado directly into your ground chicken for a super kicked up avocado flavor!Course: Main Course
Cuisine: American
Keyword: chicken burger, healthy burger, paleo burger, whole30 burger
Servings: 4 Burgers
: 262 kcal
: LaughingSpatula.com
- 1 pound ground chicken
- 1 large ripe avocado - cut into chunks
- 1 clove chopped of garlic
- 1/3 cup Panko crumbs or Almond meal to keep it Paleo and Whole30 friendly
- 1 minced Poblano or Jalapeño pepper optional but recommended
- 1/2 teaspoon salt
- 1/4 teaspoon pepper
- Add all ingredients to a large bowl and toss gently.
- Shape into desired size patties .
- Grill 4-5 minutes on each side on an indoor grill pan or an outside grill at medium heat or until the internal temperature reaches 165 degrees.
- Recipe Notes
- For best results buy avocado more on the firm side. This will ensure the chunks stay intact during mixing and cooking.
- We like a ground chicken that is 97/3. A little bit of fat makes these much tastier. Ground chicken breast can be dry.
- Grill indoors or out. We love to use our indoor grill pan for this!
Detailed recipe and credit: https://laughingspatula.com/chicken-avocado-burger/
#vegetarian #lunch #sandwich #recipe #simplerecipe #dinner #simplerecipes #healthyfood #soup #dinner #breakfast #lowcarb #healthyrecipe #easyrecipes #easyrecipe #keto #ketodiet #ketorecipes #ketogenic #ketogenicdiet


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Carmine's is one of Times Square most popular Restaurants, as well as New York City's most successful restaurants since it opened in 1992. The original first Carmine's actually opened in 1990 on the Upper West Side and was an overnight success. Known for its well diversified Italian family style servings and its wine selection at fair prices, people cannot get enough. If you want to dine here you need to make reservations well in advance, it's a great experience... Read More
Times Square new redesign
Times Square will be getting a new redesign by 2014. The Times Square Alliance says it will "simplify and de-clutter" and create a unified identity for the heart of Times Square. The $27 million plan transforms the plazas into "sleek silver-gray spaces populated by slablike benches and metallic tiles". The plan is expected to be completed in 2014. Nearby Tourist Attractions: Times Square, Times Square Visitors Center, Theatre District, Official... Read More
Times Square
Times Square, Bright lights, Big City has defined this monumental location for so many decades now. It's among the top most traveled spot in the world, possibly number 1. Its in the heart of the Theatre District, stretching along broadway from 42nd to 48th Street and on Broadway and Seventh Avenue. Times Square hosts the ball drop each year to break in the New Year at one Times Square. Its one of the most watched televised events annually. In 1904 Times Square officially... Read More
M&M's World in Times Square
M&M's World in Times Square is New York City's largest candy store, with 25,000 square feet, three-story space devoted to anything related to M&M's-themed merchandise, such as T-shirts, kitchenware, glassware, clothing, bedding, jewelry, photo frames, souvenirs, basically everything you can imagine. They also provide a variety selection of M&M's candy in 22 different colors. Nearby Tourist Attractions: Times Square Visitors Center, Theatre... Read More
HERSHEY'S Times Square
HERSHEY'S Times Square is an all American Chocolate Company. The store offers tins and jars loaded with HERSHEY'S chocolates, collectible HERSHEY'S souvenirs, HERSHEY'S clothing and toys. The back of the store has a feel of a chocolate factory and the outside of the HERSHEY'S store you will find a very unique fixture that's worth seeing. Nearby Tourist Attractions: Times Square Visitors Center, Theatre District, Official New York Visitor Center (NYCGO),... Read More
Theatre District
Theatre District in New York City is one of the most exciting places in Manhattan located in the heart of Times Square. The energetic district offers Broadway shows, off-Broadway shows, comedy clubs, restaurants, shops, and hotels catering to visitors from around the world. Bright lights, Big City was born out of this District. A lot of the shows don't end until almost midnight and its pure lights when you come out. You can find these theatres anywhere from 53rd street... Read More
TKTS ticket booth
TKTS ticket booth is at Duffy Square in Times Square, Manhattan, located between 45th and 47th Streets on Broadway and 7th Avenue. You can get discounts up to 25–50% off the face value for Broadway and Off-Broadway shows, music and dance events. The ticket booth has lots of same day tickets, so you have to get in line and wait for a bit. Nearby Tourist Attractions: Times Square Visitors Center, Theatre District, Official New York Visitor Center (NYCGO), Toys R Us Times... Read More
Duffy Square
Duffy Square is in Times Square located between 45th and 47th Streets, Broadway and Seventh Avenue. The square offers New Yorkers and visitors a place to sit and relax and take in the view of Time Square. The red steps happens to be the roof of the TKTS ticket booth, which is located behind the statue of Chaplain Francis P. Duffy, dedicated by Mayor Fiorello LaGuardia on May 2, 1937. Nearby Tourist Attractions: Times Square Visitors Center, Theatre District, Official... Read More
Times Square Information Center
Times Square Information Center is a walk-in facility at the embassy Theater, on Seventh Avenue between 46th and 47th Streets. You can stop by the Information center for details regarding tickets on broadway shows, sight seeing tours, and many other activities around the city. Open daily from 8AM to 8PM. Nearby Tourist Attractions: Times Square Visitors Center, Theatre District, Official New York Visitor Center (NYCGO), Toys R Us Times Square, M&M's World Times Square, HERSHEY'S Times... Read More


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Learning about emotions can be very difficult for children diagnosed with autism. Studies show that people diagnosed with autism are typically impaired in parts of the brain that assist in recognition of emotions and body language. Further studies are being conducted to find the most successful learning environments for children diagnosed with autism.
As I was going through music therapy journals, I came across a study done by June Katagiri, MM, MT-BC, called The Effect of Background Music and Song Texts on the Emotional Understanding of Children with Autism. This study was conducted to see what learning strategies would be most effective. During this study, twelve school children in Japan were taught four emotions, (happiness, sadness, anger, and fear) under different conditions. The four conditions included, a group with no purposeful teaching about emotions, a group with purposeful teaching only using verbal instructions, a group with verbal instructions and background music, and a group taught the emotions through singing songs. These 30-minute sessions were conducted twice a week, over a period of four weeks.
The results of this study showed that children with autism responded positively to music, therefore treatment conditions that used background music and song texts were significantly more effective. Participants were able to perceive emotions in the music, and the song texts conveyed information about the emotions that may have improved emotional understanding.
Similarly to what we have seen in our work, this article showed that using music to teach understanding of emotions can be significantly more successful than verbal instruction alone. Our new children's album will include a song written to increase emotional understanding called, "Feelings Always Change." Donate now on indiegogo to pre-order your copy!


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The 49m (161') motor yacht Rockstar is available for charter in the Bahamas over the Christmas and New Year period. Led by Captain John Parmenter, she has a highly professional crew of 10 to provide an unforgettable holiday.
A multi-activity outdoor living centre is available on the huge sundeck, complete with lounging, dining and bathing facilities, while two other decks support al fresco dining of various levels of formality.
Rockstar has luxurious accommodation for 12 guests in five comfortable staterooms. The master suite on the main deck has a king-sized double bed, while on the lower deck are three further double staterooms with king-sized beds and a twin cabin, which can convert to a queen-sized double. All staterooms have en suite facilities and HD plasma television screens.
One of the double cabins and the twin are equipped with Pullman berths to take the guest complement up to 12.
Water toys include a 5.48 metre Nautica tender, Waverunners, water skis, kayaks, snorkelling gear, fishing tackle and towables.
Rockstar is available for charter during the holiday week at $261,800 through International Yacht Collection.


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On May 28th, the PA Babe Ruth/Cal Ripken state and district staff held a Zoom meeting with representatives of the member leagues to discuss the interupted 2020 season due to the Covid-19 pandemic. We hope to see leagues offer a summer recreational program and encouraged them to investigate that possibility. The safety of our young athletes is paramount, but we feel that under the right conditions and following appropriate state and local guidelines, a viable rec season could occur. The critical benchmark will be for your county to be in the green phase. In the meantime, state and district leadership is working on a means of continued communication flow in order to share ideas and best practices as we move into the summer, and potentially, getting back on the field. We ask Presidents of our organizations to answer a brief survey about the status of their season and interest in late summer tournaments: https://bit.ly/PABabeRuthQuestionnaire
Thank you for visiting the Pennsylvania Babe Ruth & Cal Ripken homepage. Please feel free to browse around for information about the softball and baseball program offered here in PA.
We are in need of talented volunteers to join our staff...
The PA Babe Ruth/Cal Ripken program is growing, and we need your help. The state leadership is looking to expand and need volutneers interested in getting involved. We are looking to fill the following positions:
* Webmaster: Responsibilities include working with the Social Media director, but focusing on the two main websites for PA Babe Ruth/Cal Ripken, to share information with the member leagues and bring innovative new ideas to improve our communication strategy.
* Fundraising: Responsibilities include working with the state staff, and in particular the treasurer, to focus on efforts to raise money for projects and initiatives directed by the state commissioner to benefit the members of PA Babe Ruth/Cal Ripken.
Please contact Bryan Walbridge if you are interested in learning more.


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Journal of Molecular Structure 688 (2004) 79–86 www.elsevier.com/locate/molstruc Structures and vibrational spectra of indole carboxylic acids. Part I. Indole-2-carboxylic acid Barbara Morzyk-Ociepaa, Danuta Michalskab,*, Adam Pietraszkoc a Institute of Chemistry and Environmental Protection, Pedagogical University, Al. Armii Krajowej 13/15, 42-200 Cze˛stochowa, Poland b Institute of Inorganic Chemistry, Wrocław University of Technology, ul. Smoluchowskiego 23, 50-370 Wroclaw, Poland c Institute of Low Temperature and Structural Research, Polish Academy of Science, ul. Okólna 2, 50-950 Wroclaw, Poland Received 30 July 2003; accepted 24 September 2003 Abstract The crystal and molecular structures of indole-2-carboxylic acid (ICA) have been determined using single crystal X-ray diffraction, infrared spectroscopy and theoretical methods. The crystals are orthorhombic, space group Pna21, with a ¼ 30:144ð6Þ Å, b ¼ 6:466ð1Þ Å, c ¼ 3:819ð1Þ Å, V ¼ 744:4ð3Þ Å3 and z ¼ 2: The structure analysis revealed that two chains of ICA molecules form a planar ribbon, held together by intermolecular O – H· · ·O and N– H· · ·O hydrogen bonds. Both the O – H and N – H groups act as the donors, while the O atom of the carboxylic group is the acceptor of two hydrogen bonds. The carboxylic groups of ICA molecules in two chains are oriented perpendicularly to each other, which leads to formation of the zig-zag pattern of intermolecular hydrogen bond. Interestingly, the molecular layers, separated by about 3.819 Å in a stack, form a herringbone-like arrangement with the adjacent stacks. Theoretical studies of the four possible conformers of ICA monomer have been performed with ab initio (HF and MP2) and density functional (B3LYP) methods. The calculated bond lengths and angles of the most stable structure are in good agreement with the corresponding experimental results. The infrared spectrum of ICA in the solid state well supports the results from X-ray analysis. q 2003 Elsevier B.V. All rights reserved. Keywords: Indole-2-carboxylic acid; Crystal; Molecular structure; Hydrogen bond; Ab initio; Density functional calculations; Infrared spectra 1. Introduction The increasing interest in indole-2-carboxylic acid (ICA) and its derivatives is mainly due to their various biological activities: anticonvulsant effects [1,2]; antihypertensive [3]; antiarrhytmic [4] and antifungal [5,6] properties. Indole-2carboxylic acid hydrochloride is an active antagonist with high affinity for the N-methyl-D -aspartate (NMDA) receptor glycine-binding sites [7]. ICA has been applied for evaluation of the effect of glycine site antagonist on memory and motor dysfunction following brain injury [8]. The crystal structure of 3-bromobenzoyloctahydro-1Hindole-2-carboxylic acid has been reported [9]. Molecular cocrystals of ICA with 2-aminopyrimidine [10]; 5-nitroquinoline [11]; 3,5-dinitrobenzoic acid [12]; 2-aminothiazoles [13]; 4,4-dipyridyl [14]; 2-amino-5-chlorobenzooxazole [15] and sulfamethazine [16] have been prepared and * Corresponding author. Tel.: þ 48-71-203759; fax: þ 8-71-224330. E-mail address: [email protected] (D. Michalska). 0022-2860/$ - see front matter q 2003 Elsevier B.V. All rights reserved. doi:10.1016/j.molstruc.2003.09.027 studied by X-ray diffraction techniques. However, no single crystal X-ray diffraction analysis has been performed for indole-2-carboxylic acid, as yet. In this work, we report for the first time, the crystal and molecular structure of the title molecule. The ab initio (HF and MP2) as well as density functional (DFT) methods have been applied to calculate the energy and geometrical parameters of four possible conformers of ICA. The results from X-ray analysis are supported by the infrared spectra. 2. Experimental 2.1. Preparation of crystals of indole-2-carboxylic acid Crystals of ICA were prepared as follows: to a suspension of 1 mmol (0.161 g) of ICA (Lancaster) in ethanol (50 cm3) was added 1 mmol (0.075 g) of KCl dissolved in H2O (10 cm3). The mixture was heated to 80 B. Morzyk-Ociepa et al. / Journal of Molecular Structure 688 (2004) 79–86 Table 1 Crystal data and structure refinement for indole-2-carboxylic acid (ICA) Empirical formula Formula weight Temperature (K) Crystal system Space group Unit cell dimensions (Å) Volume (Å3) Z (molecule/cell) Density calculated (Mg m23) Crystal size (mm) Absorption coefficient (mm21) Fð000Þ Theta range for data collection (8) Reflections collected/unique Independent reflections Data/restraints/parameters Goodness-of-fit on F 2 Final R indices ½I . 2sigmaðIÞ R indices (all data) C9H7NO2 161.15 293(2) Orthorhombic Pna21 a ¼ 30:144ð6Þ b ¼ 6:466ð1Þ c ¼ 3:819ð1Þ 744.4(3) 4 1.438 0.28 £ 0.21 £ 0.19 0.103 336 4.62–26.0 6272/1392 ½RðintÞ ¼ 0:0644 1392 1392/1/138 0.899 R1 ¼ 0:0414; wR2 ¼ 0:0635 R1 ¼ 0:0743; wR2 ¼ 0:0741 240 K until ICA dissolved completely. After a week, yellow-crystals of ICA were formed. 2.2. X-ray analysis The X-ray diffraction data were collected using an automatic X-ray four-circle EXCALIBUR single crystal diffractometer with CCD area detectors. Graphite monochromated Mo Ka radiation (l ¼ 0:071073 nm) was generated at 50 kV and 25 mA. A single image for 18 rotation around the v-axis was obtained during 30 s and the full set of X-ray diffraction was collected in the u angle over the range from 4.62 to 26.08. The intensities of the reflections were recorded in 900 frames (each frame consisting of 512 £ 512 pixels with 2 £ 2 pixels binning). The lattice parameters were calculated from refinement of positions of all measured reflections. The data were corrected for Lorentz and polarization effects. No absorption correction was applied. The structure was solved by direct methods (program SHELXS-97 [17] and refined by the full-matrix least-squares method based on F 2 using SHELXL-97 [18]. All non-hydrogen atoms were refined anisotropically by unit-weighted full-matrix least-square methods. Hydrogen atoms were included from the difference Fourier Dr maps and refined with isotropic thermal parameters. Several cycles of refinement reduced the R value to 0.041 and wR2 to 0.063 for 1392 independent reflections. The crystal data together with the refinement details are given in Table 1. 2.3. Infrared measurements The FT-infrared spectrum of solid ICA in the region 4000– 400 cm21 was measured on a Nicolet-Nexus spectrometer using the KBr pellets. 2.4. Theoretical methods Calculations were performed by the HF and MP2 methods and B3LYP functional [19,20]. Two basis sets were employed: 6-311þ þ G(df,p), in HF method, and 6311þ þ G(d,p) [21,22] in B3LYP and MP2 methods. All calculations were carried out with the Gaussian 98 package [23]. 3. Results and discussion 3.1. Theoretical studies on the conformers of indole-2carboxylic acid Full optimization of geometry has been performed for four possible ICA conformers, which differ in the relative orientation of atoms in the carboxylic group, as shown in Fig. 1. Structure I (in which the OH group is in the anti- Fig. 1. Relative differences in energy ðDEÞ between four conformers of ICA. The minimum energy values (in kcal mol21) are as follows: 2344665.1 (HF); 2346734.3 (B3LYP) and 2345776.4 (MP2). B. Morzyk-Ociepa et al. / Journal of Molecular Structure 688 (2004) 79–86 81 Table 2 The selected bond lengths (Å) and bond angles (8), with e.s.d.s. in parentheses, determined for ICA by X-ray diffraction and the corresponding theoretical parameters, calculated for conformer I by the HF, B3LYP and MP2 methods Exp. Fig. 2. Overall view of indole-2-carboxylic acid (ICA) with atom labeling. position to the N –H group) is the most stable, as revealed by calculations at the HF, MP2 and DFT(B3LYP) levels of theory. Conformer II is slightly higher in energy, by about 1.1 –1.4 kcal mol21. In this isomer, the COOH group has rotated (by 1808), in comparison to I. Remaining conformers, III and IV are higher in energy, by about 5 kcal mol21. Subsequent calculations of vibrational frequencies have revealed that both I and II are stable, in the gas phase. 3.2. Description of the structure The overall view of ICA molecule with atom labeling is shown in Fig. 2. The single crystal X-ray diffraction study indicates the presence of conformer I in crystal. Selected bond lengths and angles are listed in Table 2, along with the corresponding theoretical values calculated by the HF, MP2 and B3LYP methods. It should be noted that the calculations have been performed for an isolated ICA molecule, in the gas phase, but agreement between the theoretical and experimental results is quite good. Some deviations from the experimentally observed values can be attributed to hydrogen bonds in the solid state. As follows from Table 2, the C0 – O1 bond length of 1.227(1) Å is slightly longer than the theoretical values, and this is caused by intermolecular hydrogen bonding in crystal. It should be emphasized that the calculated bond angles show very good agreement with experimental data. For example, the B3LYP-predicted angles: O1 –C0 – O2 (122.98) and O2 – C0 – C1 (113.18) agree well with experimental, 121.6(1) and 112.5(1)8, respectively. Several bond angles, e.g. N1 –C1 – C2 (109.48) are almost reproduced by the B3LYP calculation, as shown in Table 2. The biggest deviation between the calculated and experimental bond angle is noted for the C0 –O2 – H11 group. This is attributed to intermolecular hydrogen bonding in the crystal of ICA, which leads to an increase (opening) of the C0 – O2 – H11 angle, by about 108, in comparison with the theoretical value of the isolated monomer. O(1) –C(0) O(2) –C(0) O(2) –H(11) C(0)–C(1) C(1)–C(2) C(1)–N(1) C(2)–C(3) C(2)–H(1) C(3)–C(8) C(3)–C(4) C(4)–C(5) C(4)–H(4) C(5)–C(6) C(5)–H(5) C(6)–C(7) C(6)–H(6) C(7)–C(8) C(7)–H(7) C(8)–N(1) N(1) –H(2) O(1) –C(0)–O(2) O(1) –C(0)–C(1) O(2) –C(0)–C(1) C(0)–O(2) –H(11) C(0)–C(1) –N(1) N(1) –C(1)–C(2) C(1)–C(2) –C(3) C(1)–C(2) –H(1) C(2)–C(3) –C(8) C(2)–C(3) –C(4) C(3)–C(4) –C(5) C(3)–C(4) –H(4) C(4)–C(5) –C(6) C(4)–C(5) –H(5) C(5)–C(6) –C(7) C(5)–C(6) –H(6) C(6)–C(7) –C(8) C(6)–C(7) –H(7) C(7)–C(8) –C(3) C(7)–C(8) –N(1) C(8)–N(1) –C(1) C(1)–N(1) –H(2) 1.227(1) 1.326(1) 0.951(11) 1.439(1) 1.369(1) 1.384(1) 1.416(2) 0.932(9) 1.403(1) 1.409(2) 1.357(2) 0.974(8) 1.404(2) 0.964(8) 1.372(2) 1.026(11) 1.390(2) 1.045(10) 1.383(1) 0.968(11) 121.6(1) 125.9(1) 112.5(1) 116.0(6) 121.8(1) 109.4(1) 107.6(1) 125.3(6) 106.9(1) 134.2(1) 118.7(1) 117.0(5) 121.4(1) 121.2(5) 121.5(1) 117.7(6) 117.2(1) 122.6(6) 122.2(1) 129.6(1) 107.9(1) 122.9(7) HF 1.187 1.332 0.945 1.467 1.352 1.371 1.432 1.070 1.400 1.401 1.368 1.076 1.409 1.075 1.368 1.075 1.398 1.075 1.359 0.992 123.1 123.5 113.4 108.9 119.0 110.1 106.5 125.8 106.7 133.8 118.9 120.4 120.8 120.1 121.7 119.0 117.4 121.2 121.8 130.2 108.7 126.0 B3LYP 1.214 1.354 0.968 1.459 1.378 1.384 1.427 1.078 1.426 1.408 1.383 1.084 1.413 1.084 1.385 1.084 1.400 1.084 1.371 1.008 122.9 124.0 113.1 106.9 118.6 109.4 106.9 125.3 107.0 134.0 118.9 120.4 121.1 119.8 121.6 119.2 117.4 121.2 122.0 130.6 109.2 123.1 MP2 1.218 1.352 0.969 1.464 1.390 1.376 1.427 1.082 1.430 1.414 1.389 1.087 1.418 1.087 1.391 1.087 1.404 1.087 1.373 1.012 123.7 123.7 112.6 105.9 118.3 109.6 106.5 125.3 107.1 134.0 118.7 120.4 121.4 119.6 121.4 119.3 117.2 121.2 122.3 130.3 109.4 123.1 According to the X-ray results, the conjugated sixmembered and five-membered rings of indole part are nearly coplanar, for example, the C2 – C3 –C8 – C7 torsional angle is 179.0(1)8, and N1 –C1 – C2 – C3 torsional angle is nearly zero (0.1(1)8). The carboxylic group of ICA shows only a small distortion from the molecular plane: the dihedral angle between the best least-squares planes formed by the indole ring atoms (C1, C2, C3, C4, C5, C6, C7, C8 and N1) plane I, and the carboxylic group atoms (C0, O1 and O2) plane II, is 2.98(0.13)8. Comparison of the X-ray data of ICA (this work) and those of the parent indole [24] indicates that the presence of 82 B. Morzyk-Ociepa et al. / Journal of Molecular Structure 688 (2004) 79–86 Table 3 Hydrogen bonds distances (Å) and angles (8) in ICA D –H· · ·A D –H H· · ·A D· · ·A /D–H· · ·A O(2) –H(11)· · ·O(1)i N(1) –H(2)· · ·O(1)ii 0.951(11) 0.969(11) 1.749(11) 2.172(11) 2.659(1) 3.118(1) 159.2(10) 165.3(10) Symmetry transformations used to generate equivalent atoms: (i) 2x þ 3=2; y þ 1=2; z þ 1=2; (ii) 2x þ 3=2; y 2 1=2; z 2 1=2: the carboxylic group affects the bond lengths and angles in the conjugated rings. For example, in ICA, the N1 –C1 and N1 – C8 bond lengths are longer (1.384(1) and 1.383(1) Å, respectively) than in indole (1.370 Å). On the other hand, both the C3 – C4 and C4 – C5 bonds in ICA (1.409(2) and 1.357(2) Å, respectively) are shorter than the corresponding bands in indole molecule (1.425 and 1.382 Å). It should also be noted that in ICA, the C3 – C8 bond length (1.403(1) Å) is elongated, in comparison to indole (1.382 Å) [24]. Hydrogen bond lengths and bond angles of ICA are shown in Table 3. Fig. 3 illustrates the H-bond pattern in the crystal. The planar ribbon consists of two chains of molecules held together by intermolecular hydrogen bonds. It should be emphasized that the pattern of the intermolecular hydrogen bonding is different than that observed in typical cyclic carboxylic acid dimers. It is seen that the carboxylic group of the ICA molecule in one chain is facing almost perpendicularly to the direction of the carboxylic group in the other chain. This is caused by the fact that ICA contains two hydrogen-bond donor sites, the carboxylic O2 –H and indole N1 –H groups which point toward an approximately orthogonal directions. Both the O2 – H11 and N1 – H2 groups act as donor sites, while the O1 atom acts as the acceptor site for two hydrogen bonds, as shown in Table 3 and in Fig. 3. Of the two hydrogen bonds, O2 – H11· · ·(O1)i (i: 2x þ 3=2; y þ 1=2; z þ 1=2) and N1 – H2· · ·(O1)ii (ii: 2x þ 3=2; y 2 1=2; z 2 1=2) with the D· · ·A distances of 2.659 and 3.118 Å, and /D –H· · ·A angles of 159.2 and 165.38, respectively, the former is of a moderate strength, while the latter (N –H· · ·O) is much weaker. Interestingly, these hydrogen bonds form the nine-membered rings, which share the common C0 –O1 bond. This leads to a zig-zag structure of the H-bonded rings. Fig. 4 shows the packing arrangement of the molecules in the unit cell, viewed down c-axis. The ribbons containing the nine-membered hydrogen bonded zigzag rings are running along the b-axis. Fig. 5 shows the projection of the crystal structure on the 011 plane. It is interesting that the parallel layers consisting of molecular ribbons in one stack (column) are in a skew orientation with respect to the layers in the adjacent stacks. It should be noted that the carboxylic oxygen atoms in one layer are positioned above (or below) the oxygen atoms in the neighboring layers. Such an arrangement increases repulsion between the lone electron pairs of the oxygen atoms in the parallel layers, which decreases p – p stacking interaction between the aromatic rings in the neighboring layers. Consequently, these effects increase the distance between the parallel layers, to 3.819 Å. Fig. 3. The hydrogen bonding pattern in ICA (H-bonds are indicated by dashed lines). B. Morzyk-Ociepa et al. / Journal of Molecular Structure 688 (2004) 79–86 83 Fig. 4. The arrangement of the ICA molecules in the unit cell, viewed down c-axis. Fig. 6 shows the projection of ICA crystal down the aaxis. It is seen that the planar layers form a herringbone-like arrangement between the adjacent stack. The torsion angle between the two adjacent stacks (determined as the angle between the normals to planes defined by indole rings of ICA molecules, in adjacent stacks) is equal to 49.58. This is a measure of the twist of ICA molecules in one stack with respect to those in an adjacent stack. It should be mentioned that very recently, a similar packing arrangement has been reported for 1,2,4,5-tetrazines [25]. 3.3. Infrared spectrum The infrared spectrum of indole-2-carboxylic acid in the solid state (KBr pellets) is shown in Fig. 7. Recently, Tine et al. [26] studied the infrared spectrum of ICA, assuming that the two molecules form cyclic dimer associated by two O – H· · ·O hydrogen bonds, typical of carboxylic acid dimers, while the N – H group of ICA is not involved in hydrogen bonding. As we have shown in this work, the structure assumed by those authors was incorrect, since both the O –H and N – H groups of ICA (oriented in nearly orthogonal directions) act as the donors of hydrogen bonds. The strong band in the IR spectrum of ICA, at 3350 cm21, can be assigned to nðN – HÞ stretching vibration of the molecules associated by intermolecular N – H· · ·O hydrogen bond. In addition, a small satellite band is observed at 3453 cm21. Most probably, the latter band arises from the non-associated, end N –H groups of the ICA chains in the crystal. A strong and very broad band occurring between 3200 and 2000 cm21 is due to the nðO – HÞ stretching mode of the OH group involved in intermolecular O –H· · ·O hydrogen bond. Significant lowering and broadening of the nðO – HÞ band indicates that the O – H· · ·O hydrogen bond is stronger than N –H· · ·O hydrogen bond, which is confirmed by the X-ray data of ICA. The very strong band at 1707 cm21 is assigned to the nðCyOÞ stretching vibration. The frequency of this vibration is slightly lower than the frequency of the non-associated carboxylic CyO group in 9,10-dihydro-9-oxo-10-acridineacetic acid (1737 cm21) [27]. This supports the conclusion that in the crystal of ICA, the CyO group participates in intermolecular hydrogen bonding. It should also be noted, that the CyO bond arising from the cyclic dimer of acetic acid was observed at 1681.5 cm21, in the gaseous state [28]. In the IR spectrum of ICA, the strongest band appearing at 1194 cm21 can be assigned to the nðC – OÞ stretching vibration in the carboxylic group. Thus, the large difference between the frequencies of nðCyOÞ and nðC – OÞ stretching vibrations of the carboxylic group excludes the possibility of the existence of deprotonated B. Morzyk-Ociepa et al. / Journal of Molecular Structure 688 (2004) 79–86 Fig. 5. Projection of the crystal structure of ICA on the 011 plane. 84 B. Morzyk-Ociepa et al. / Journal of Molecular Structure 688 (2004) 79–86 85 Fig. 6. Projection of the crystal structure of ICA along the a-axis. Fig. 7. The infrared spectrum of indole-2-carboxylic acid. ICA in crystal. In should be noted that in the IR spectrum of sodium indole-2-carboxylate (in solid state), two strong bands at 1562 and 1409 cm21 were assigned to asymmetric na ðCOO2 Þ and symmetric ns ðCOO2 Þ stretching vibrations, respectively [26]. The presented assignment of the characteristic vibrations of ICA in the IR spectrum provides additional evidence for the structure and hydrogen bonding determined by the X-ray method. This assignment can be useful in further studies of complexes of indolecarboxylic acids with metal ions, by vibrational spectroscopic methods. Acknowledgements The authors are grateful to the Wroclaw Supercomputer and Networking Center for a generous computer time. Supporting Information The crystallographic data of the title compound in CIF electronic format are available at http://www.rscorg/ supdata/CCDC216179. 86 B. Morzyk-Ociepa et al. / Journal of Molecular Structure 688 (2004) 79–86 References [1] A.C. Nichols, K.L. Yielding, Mol. Chem. Neuropathol. 19 (1993) 269. [2] M. Mugnaini, M. Antolini, M. Corsi, F.T. Vanamsterdam, J. Recept. Signal Transduct. Res. 18 (1998) 91. [3] S. Nagata, K. Takeyama, F. Fukuya, R. Nagai, K. Hosoki, K. Nishimura, T. Deguchi, T. Karasawa, Arzneimittel-Forschung/Drug Res. 45 (1995) 853. [4] M.I. Vlasova, N.A. Kogan, Y.Y. Lesiovskaya, L.V. Pastushenkov, Khimico-Farmatsevticheskii Zh. 26 (1992) 23. [5] C. Kipp, A.R. Young, Photochem. Photobiol. 70 (1999) 191. [6] P. Kutschy, M. Dzurilla, M. Takasugi, A. Sabova, Coll. Czech. Chem. Commun. 64 (1999) 348. [7] K. Ohtani, H. Tanaka, Y. Yoneda, H. Yasuda, A. Ito, R. Nagata, M. Nakamura, Brain Res. 944 (2002) 165. [8] D.H. Smith, K. Okiyama, M.J. Thomas, T.K. McIntosh, J. Neurosci. 13 (1993) 5383. [9] C.J. Blankley, J.S. Kaltenbronn, D.E. DeJohn, A. Werner, L.R. Bennett, G. Bobowski, U. Krolls, D.R. Johnson, W.M. Pearlman, M.L. Hoefle, A.D. Essenburg, D.M. Cohen, H.R. Kaplan, J. Med. Chem. 30 (1987) 992. [10] D.E. Lynch, T. Latif, G. Smith, K.A. Byriel, C.H.L. Kennard, J. Chem. Crystallogr. 27 (1997) 567. [11] D.E. Lynch, N. Mistry, G. Smith, K.A. Byriel, C.H.L. Kennard, Aust. J. Chem. 51 (1998) 813. [12] D.E. Lynch, G. Smith, K.A. Byriel, C.H.L. Kennard, Aust. J. Chem. 51 (1998) 1019. [13] D.E. Lynch, L.J. Nicholls, G. Smith, K.A. Byriel, C.H.L. Kennard, Acta Crystallogr. 55B (1999) 758. [14] D.E. Lynch, S. Chatwin, S. Parsons, Cryst. Engng 2 (1999) 137. [15] D.E. Lynch, M. Singh, S. Parsons, Cryst. Engng 3 (2000) 71. [16] D.E. Lynch, P. Sandhu, S. Parsons, Aust. J. Chem. 53 (2000) 383. [17] G.M. Sheldrick, SHELXS-97, Program for the Solution of Crystal Structures, University of Göttingen, Germany, 1997. [18] G.M. Sheldrick, SHELXL-97, Program for the Refinement of Crystal Structures, University of Göttingen, Germany, 1997. [19] A.D. Becke, J. Chem. Phys. 104 (1996) 1040. [20] C. Lee, W. Yang, R.G. Parr, Phys. Rev. B 37 (1988) 785. [21] R. Krishnan, J.S. Binkley, R. Seeger, J.A. Pople, J. Chem. Phys. 72 (1980) 650. [22] M.J. Frisch, J.A. Pople, J.S. Binkley, J. Chem. Phys. 80 (1984) 3265. [23] M.J. Frisch, G.W. Trucks, H.B. Schlegel, G.E. Scuseria, M.A. Robb, J.R. Cheeseman, V.G. Zakrzewski, J.A. Montgomery, Jr., R.E. Stratmann, J.C. Burant, S. Dapprich, J.M. Millam, A.D. Daniels, K.N. Kudin, M.C. Strain, O. Farkas, J. Tomasi, V. Barone, M. Cossi, R. Cammi, B. Mennucci, C. Pomelli, C. Adamo, S. Clifford, J. Ochterski, G.A. Petersson, P.Y. Ayala, Q. Cui, K. Morokuma, D.K. Malick, A.D. Rabuck, K. Raghavachari, J.B. Foresman, J. Cioslowski, J.V. Ortiz, A.G. Baboul, B.B. Stefanov, G. Liu, A. Liashenko, P. Piskorz, I. Komaromi, R. Gomperts, R.L. Martin, D.J. Fox, T. Keith, M.A. Al-Laham, C.Y. Peng, A. Nanayakkara, C. Gonzales, M. Challacombe, P.M.W. Gill, B. Johnson, W. Chen, M.W. Wong, J.L. Andres, C. Gonzalez, M. Head-Gordon, E.S. Replogle, J.A. Pople, GAUSSIAN 98, Revision A.1, Gaussian, Inc., Pittsburgh PA, 1998. [24] P. Roychowdhury, B.S. Basak, Acta Crystallogr. B31 (1975) 1559. [25] N.S. Oxtoby, A.J. Blake, N.R. Champness, C. Wilson, Cryst. Engng Commun. 5 (2003) 82. [26] A. Tine, P. Guillaume, A. Massat, J.J. Aaron, Spectrochim. Acta, A 54 (1998) 1451. [27] D. Dobrzyńska, I. Turowska-Tyrk, Acta Crystallogr. C53 (1997) 238. [28] J.E. Bertie, K.H. Michaelian, J. Chem. Phys. 77 (1982) 5267.


text:
This question comes up a lot on the various forums. You often see people seeking absolution or beating themselves up because they had a cheeseburger. People appear to view this from two extreme angles. On the one hand you have some saying "is it absolutely NOT okay to cheat on the pre-op" while others will give examples of how they cheated and nothing bad happened. So it is okay or is it not?
Pre-ops vary a lot from no pre-op diet to a full liquids diet, to some food allowed, to a clear liquids only diet. Fair to say, anyone who has to do even a week of liquids does have a hard time. We're given two reasons why we have to do the pre-op. Most commonly, it's because it's meant to shrink our livers so that they don't interfere with the surgery on our stomachs. But even here, professionals do not agree. Some doctors believe it helps, others will tell you it takes longer than a couple of weeks to treat a fatty liver. We've all also heard stories about patients who did not follow their pre-op and woke up to find the doctor had not completed the surgery.
The second reason we're given is to help us detox and learn new habits. If you stop for a moment and think of what you will be giving up during the pre-op, many of which you will not be picking up post-op for quite a well, here are just a few things:
1. No caffeine. Aaargh!
2. Carbs below 50 gms a day
3. Less than 1000 calories a day
4. Much more protein than we usually intake
5. Liquids only plus veg soup (in my case). Not easy.
6. No straws
7. No fat to speak of
8. No sugar
9. No fruit
10. No carbonated beverages
No wonder people struggle. But here's the thing.
The pre-op is totally doable.
It's tough, but doable. You sort of have to take it one day at a time. Here's why I didn't cheat.
First, I was facing a major change in my way of living, and I wanted to get ready for it. Second, I was facing major surgery. I am not a medical doctor, I have no idea whether it shrinks my liver or not, but if I trusted a doctor to take out 85% of my stomach, then I was going to trust his advice on the pre-op. Third, I needed to feel in control. My biggest problem with food was that I felt out of control with it. Not because I ate too much, but because no matter what I ate, I seemed to put on weight.
The liquid diet put ME back in control. I wasn't being driven by food, I set a routine, and I drank my shake and ate my soup according to the clock .
The first four days were hellish. I needed a nap all the time, I was exhausted and I worried that I would never make it through and still be able to make a living.
On the fifth day, a switch flipped and all my old energy came rushing back. My experience is not unusual. Everyone tells you the first few days are no fun. Start your diet on a Friday and allow yourself to sleep through most of the weekend, and you will do better.
I went into the surgery feeling very confident that I could follow the rules set forth by my doctor, and I am glad I didn't cheat myself out of that win. I felt in control, calm, and like I had a handle on what was about to come.
What if you did cheat though?
Again, people's opinions vary. Some will tell you this means that you will fail post op, while others will tell you to get back on the horse and give it your best shot. No matter how you approach this, I do think you should let your surgeon know. Sometimes they can come up with slightly modified guidelines so your pre-op is easier, at other times they can give you tips on what to do.
We've all heard horror stories of people who ate before surgery and ended up with complications, leaks, etc. You don't want to risk it. Let your surgeon know, and do what they tell you to. It's all good. 🙂


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Malia Mills Sample Sale
If you're already a fan, or if you're not yet, you'll be stoked to hear that Malia Mills is having sample sale. Get some of their signature bra sized swim separates and maillots -- sizes AA to E and 2 to 16. Some super fly Malia Mills ready to wear too -- All of this up to 75% off retail prices. Gimme some of that!
At Malia Mills love thy differences is their rallye cry! They make impeccably chic products with badass sass -- in the heart of the Garment Center in NYC, across the Hudson in the great state of New Jersey, in the Golden State that is California and in Haryana, India. One world!
Wednesday at NOON EST – Friday at 9:00PM EST
2014-09-17T00:00:002014-09-19T00:00:00Pacific/MidwayMalia Mills Sample Sale - Online - September 2014Malia Mills Sample Sale - Online - September 2014, CA
Online Sale @