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The Relative Worth of Human and Animal Life
This might seem like an odd question, but, to put it bluntly: do you believe that human life should be regarded as being more important than animal life?
First, I would like to establish right away that this question is to be taken purely from a rational perspective; while your religion, for instance, might assert that humans are inherently more valuable than animals, or vice versa, I would request that it is not considered for the purposes of this question. Equally, I also request that no expression of moral superiority or inferiority is made between those who participate in this debate. From my own perspective, I value human life over animal life (though I am concerned with conservation of animal life and the environment). I eat fish and I like it. However, I have not been able to personally find a moral justification for considering human life more important than animal life. This, for me, gives rise to some cognitive dissonance.
Now, to specify the parameters on which this question is based: let us right away eliminate from the equation animals that pose an active threat to humans (such as mosquitoes), or animals that might be compromised for the sake of scientific advancement, as these would complicate an already nuanced question in an unnecessary direction.
Additionally, it should be noted that the question does not refer to the personal, subjective value that one sees in something or someone. For instance, one might value one's friends and loved ones over strangers, but they are ultimately no more important (by default, assuming nothing is known about their personalities or actions) from an objective point of view. Certainly, it is only natural to consider one's friends and loved ones more important than strangers, one's own species more important than others. But it being natural does not necessarily mean it is correct; it cannot be used as justification for a position that humans are more valuable simply by virtue of being the same species as us. I would argue against it on the same grounds on which I would argue against nationalism or racism. That is, I would argue against moral myopia. Self-centered morality is not formulated from an objective standpoint, and it is thus invalid.
If my thinking runs correct here -- and if not, do correct me -- the question would then come down to a matter of whether humans have some intrinsic quality that renders them more valuable than other animals. Else there could exist no moral justification to value human lives more.
A quick answer would be that humans are more intelligent. They are capable not only of rationality but also of morality. Animals are not as self-aware as we are; identity is not as strong a concept for them. After all, very few animals ever pass the mirror test for self-recognition. Animals are lesser beings not just for not possessing our intelligence, but also because they are immoral. If they would not show morality towards us, why should we show them the same?
However, this argument is undermined by the fact that even among humans, intelligence is not equally distributed. Some individuals are more intelligent than others. At the same time, some suffer from mental illnesses, through no fault whatsoever of their own, that could inhibit their rationality. These people should not face any discrimination, especially as they are generally harmless. Even those that do commit serious crimes can seek the insanity defense (although "empirical research reveals that the insanity defense is seldom used and is seldom successful"), so the concept that those who are inhibited morally or rationally should be held less accountable for their actions extends to the legal system. If this is the case between humans, I see no reason why it should be any different for animals. Then, can it really be said that animals should be considered less valuable than humans on grounds of their lesser intelligence, even though it is a matter of their circumstances of birth and not their own fault? That could only be true if more intelligent humans are also considered more important than less intelligent ones.
You would note that it is here that the point about excluding actively dangerous animals such as mosquitoes becomes relevant. It accounts for the point that less intelligent beings could potentially be dangerous, and thus keeping them in check is simply a practical means of minimizing damage.
Similarly, I would find it hard to digest a possible argument that suggests that the demonstrated ability of humans to dominate other animals is itself proof of their superiority, just as I cannot agree that humans who dominate other humans are automatically superior to them.
But if indeed animals were given rights equal to those of humans, that would raise an entire slew of questions. Would it mean that humans should give up farming animals for food? And if the difference in intelligence indeed does not matter, would that not mean that plants (who in fact do show some "self-awareness" in the case of certain species to the point that they can recognize family members* and exhibit some "intelligence" not only in their complex chemical-based communication but also in their ability for memory and learning by association) should also be granted the same? What is the logical conclusion of such an approach that disregards intelligence as a criterion for value? Would fungi, protista and monera then also deserve the same value?
In fact, can "animal life" even be grouped together in such a manner? Surely some animals are seen as more valuable than others. A dog or cat is certainly seen as more valuable than, say, a snail; a horse more than a fly. But is this appropriate, only a reflection of the gradation of animal intelligence, intrinsic worth and self-awareness? Or is it merely an arbitrary distinction that is based only on humans' selfish desire to see other animals in terms of how useful they are to humans, one that bears no grounds in morality?
This question becomes more complex when one considers that most would do more for their pet dog than poor strangers on the streets -- that is, in that case, an animal is being favoured over a human simply by virtue of emotional proximity. On the other side of the coin, there are indeed some cases I can think of where a mentally competent person would be actively selected over someone less so. For example, in case of limited resources, it would only be Utilitarian to use them to help an injured but mentally sound individual than one who has sustained enough brain damage to be rendered little more than a vegetable, as the latter's life would not be a good one and they would not be able to appreciate being alive as much as the mentally sound person could. Is it that intelligence does matter, but only to some extent?
It is in this light that I reiterate my question. Is the fact that human lives are granted greater import than the lives of other animals, and moreover that some animals are considered more valuable than others, merely a product of our selfish attachment to those who are close to us? Or is it grounded in practicality, with animals being far too useful to us for them to be granted an equal standing? Or, perhaps, is it possible that there could indeed be some moral basis for this along with the other two factors?
Please state your views.
* - In addition to the contents of the article, as seen in this documentary, this recognition of siblings is based on active communication, not something that is constant, set-in-stone once activated. This can be demonstrated by the fact that if the communication between two neighbouring siblings is blocked, they will almost immediately start behaving as if the other plant is a stranger, ramping up root growth.
Last edited by Mew The Gato; 02-12-2018 at 04:08 PM.
I'm going to twist your question a bit before presenting my answer (spoiler: I value animal and human life as equally sacred):
There is a new type of meat called Impossible Meat. I read in SNR a week ago that a new restaurant selling burgers made from impossible beef will open in Downtown Sacramento. Impossible Meat, unlike laboratory-derived meat using animal tissue to begot animal tissue, is structurally recreated to resemble animal proteins but is built from plant material.
This is notable because the first debut of Impossible Meat was a disaster. The vegans invited to the trial refused to sample the meat, believing the entire event was a conspiracy to get them to eat meat.
The incident was interesting to me because, while there are certainly many philosophies behind veganism, one of them is animal welfare. Why would people react so strongly against eating meat if their MO was philosophical? That kind of strong rejection is more in line with the spiritual kashrut adherence, which seems anathema to what most vegans are.
So what about normal people? If you had the choice between a fake, otherwise indistinguishable burger and a burger made by brutally killing an animal, it would only make sense to go for the veggie burger, right? Most humans would go for the animal because the former "isn't natural". Which tells me that humans, on the whole, do not value life that highly.
Truly a violent, sexist, destructive race, no?
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The closer an animal is to an automaton, the less inclined I am to consider its life as sacred as a human's. The closer an animal is to a human, the more inclined I am to consider its life equally sacred as a human's.
Automaton examples: earthworms, sea jellies, silverfish
Human examples: primates, felines, canines, birds
The less sapient the animal is, the closer it is to a Roomba than a person, the less inclined I am to value its life. I'm not haunted by YouTube videos of Roombas smashed to pieces by bowling balls dropped from great heights for people's amusement on YouTube. I'm haunted by the stories I heard second hand from friends frequenting 4chan back in the mid-00's of sick fucks in China (disturbing, so boxed)
Spoiler: show
crushing rabbits and gerbils to death beneath panes of thick sheet glass by sitting on the upper pane and crushing the trapped animal underneath.
Of course, there's a lot of gray in the middle. Yours is not an easy question with easy answers. I can hide in the extremes and say, "I'd rather we blended up this poor innocent sea jelly than execute this shoplifter," but it becomes a bit harder, a bit more uncomfortable, for me to reflect on my position regarding most arthropods. Take grasshoppers, for example. My kneerjerk reaction is "Grasshoppers aren't sapient," "Grasshoppers matter much less than people," ... but I would still be unable to defend someone who tears off a leg from a grasshopper, not only because the person is behaving sickly but because even if I want to say the grasshopper is little more than a chitinous Roomba he's still flailing and squirming about in such apparent "anguish" that it challenges my use of the air quotes just there -- for how can I be certain that it is not very real anguish, felt by a very real and very distressed cognizant being?
tl;dr animal cruelty bites and people who mock pet owners who treat their pets as genuine members of the family can piss off, but it's hard to defend why it's okay to kill some dogs (cows) but not others (actual dogs).
Alright, full answer.
I consider all life sacred, even automaton-like insects. Though there is a general hierarchy of vertebrates > invertebrates > plants > microbes. But there's no around it at times. Everytime you swallow you're probably killing some environmental microrganisms. Your immune system has to kill septic bacterial for you to survive. And you need animal protein to now have your own body break down.
Looking at this from the extreme religious POV - Commandment #5, "thou shalt not kill" - it applies to everything, not just "murder" or whatever that the Protestants twist it as. Given the audience of the ten commandments, it clearly refers to murder, but I don't think God was big on retrospective original intent. He spoke for the ages. The spirit of the law needed to be always upheld because God uses metaphors, so people of today following the commandments can't use the Sinai context when applying those rules to their own lives. So, in today's terms, unnecessary killing, to the eventuality of all killing, becomes sinful.
In that sense I don't make a distinction between killing for pleasure or for food. I don't have strong opinions against cannibalism, though I do have a ritual respect of the dead. Killing is bad under all circumstances. But, someone who kills for pleasure is a problem in my book, because they're killing more than someone who kills only for food.
So do I not make a sapience distinction? In sharp contrast to Talon, I think being sentient is a responsibility. Dumb animals or automatons by default at innocently, according to their own programming. They're completely incapable of evil or knowledge of wrongdoing. But the more intelligent animals, that exhibit a capacity for empathy and sadism, the more onerous the burden to demonstrate a respect for life. Sentient animals that refuse to value life, in my view, forfeit their right to life.
I don't have any qualms about barbecuing murderers in electric chairs or cutting up killer whales into steaks. Or, fighting terrorists and violent insurgents. If it's sinful to kill these creatures, by doing so you're preventing them from killing far more.
Additionally, if given two options, it is morally correct (sinless) to pick the option that involves the least killing, and the l until the day when options exist for foods that don't involve killing at all. That is only a dream, but I think sacrificing plants over animals is a lesser evil, so things like lab meat and Impossible Meat are things I support wholeheartedly.
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There's also the possibility of wrongfully convicting people and then executing them. This is the biggest reason why I'm against the death penalty. Of course, it's also no picnic for a wrongfully convicted person to spend life in prison, but at least there's always hope that new evidence will emerge down the road that will exonerate him. The other reason is that if, as a society, you want to send the message that killing is never okay (barring self defence or other valid reason) then it's hypocritical for the state to execute people.
Smoking Gary sez:
"Stay in school kidz"
It's easier to prevent gluttony/drug addiction in the first place than to rehabilitate someone who is psychologically and/or physiologically addicted, and I equate pleasure killing to the same.
Someone who lacks empathy is a much harder scenario to evaluate, and is probably a case-by-case basis. But by and large, someone who cares little for life beyond their own logically wouldn't kill unless they had to fearing lawful punishment. So, powerful punishment is necessary to force them to behave. I don't think life in prison is a strong enough deterrent, death is the ultimate deterrent.
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There are conflicting studies on whether the death penalty prevents murder or not, but the general consensus seems to be that it doesn't. See this for example:
That's not conclusive proof of anything because maybe states without the death penalty have lower murder rates simply because they're more pleasant places, but most criminologists don't think the death penalty helps in any way. The simple reason is that most criminals don't believe that they're going to get caught. Let's face it, the reason why states/countries have the death penalty isn't for deterrence. It's because they want vengeance.
Smoking Gary sez:
"Stay in school kidz"
This topic has a bit of future-proofing built in, though: like I said with the "impossible meat" example, things that would have been impossible just 50 years ago are becoming reality now. It's possible to eat something that is almost identical to meat, but isn't sourced by killing an animal.
Consider all the feared biometric data built into phone software now, that monitors and measures everything you do to create a digital profile. One day when everything is on-grid, it will be impossible to hide crimes. So logically motivated criminals wouldn't be willing to act on premeditation, the only murderers would be those blinded by emotion (second degree), those intentionally wanting to be martyrs, or those who do not fully understand the consequences of their own actions (else they be sorted into the "logically motivated" group).
As things currently are, I don't think prisons are the worst thing in the world. But they're a crutch, ultimately a transitional tool for a state where fear of punishment leverages lawful behaviour almost absolutely.
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Humans are not motivated or deterred by the size of the punishment (up to a point) - the real question in our minds is "how likely are we to get caught?"
Your chances of getting caught speeding go up if there's a cop car nearby, so you slow down - don't want to get a ticket, even a $10 ticket! If your car could detect speeding and you would then receive a ticket in the mail, speeding would disappear completely overnight.
Cutting down on roadway deaths often involves just putting more officers on the road. If you see a cop car, you go slower because you don't want to get punished.
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As a journalist, I feel that it's my duty to provide you, the reader, with carefully researched columns that employ unbiased facts to present multiple sides of today's most complex issues. So today I'm going to use a lot of hyperbole and anecdotal evidence to write about German cars.
I came up with the idea for today's column – that the only thing less reliable than a German car is a Happy Meal wristwatch – a few weeks ago while talking to a German friend. He told me, with absolutely no hint of irony in his voice (because Germans don't have the capacity for irony; just cleanliness), that modern German cars will "last forever." He was also stunned when I began violently coughing after several minutes of uncontrollable laughter.
For some reason, Germans still believe this stuff. They actually think that modern German cars, which use the same technology for cruise control as our government uses to monitor the skies for impending nuclear warfare, will still be running perfectly in 20 years.
I have two potential theories for why Germans feel this way. One is that Germans actually know the cars are crap, but they refuse to slander Germany, so they can't ever mention this. So they go home at night and lie awake thinking about how their power trunk closer has stopped working, and now they'll have to carry around their luggage in the backseat whenever a foreigner is nearby.
The other theory is that these cars actually will live on, perfectly preserved, in Germany. This is because Germans always maintain things perfectly, in perpetuity, which is sort of contrary to how we behave here in America. For example: if a check engine light goes on in Germany, a German will rush to the dealership and have it fixed. Whereas an American will resolve the check engine light by a) going to Home Depot for some electrical tape to cover it up, and b) visiting McDonald's on the way home.
But regardless of the reason, Germans really do think their cars are built to last forever. And here's the thing: it's not only Germans who feel this way. There's also a small contingent of Americans who will tell you – no matter how hard you argue against it – that German cars will last "a million miles" without ever needing a major service. These are usually the people who get a new S-Class every three years.
Now, before we get into the reality of the situation, I'd just like to say that I understand where all of these perceptions of German car reliability come from. Mainly, they come from the old days, when German cars actually were more reliable than foreign rivals, and they were built like tanks, and evil dictators would cruise around in them because they could withstand nuclear attack and come out totally unscathed, except for those little flags mounted on the front bumpers.
But let's be honest here, folks: this is no longer the case. And it hasn't been the case for a long time.
For proof, I start with my own experience owning German cars. I've owned eight, in total: one from every important German automaker, and also Volkswagen. And they were all complete pieces of crap.
OK, so maybe they weren't that bad. Oh, sure, the transmission died in one of them. And yeah, so I had to replace the ignition switch in another, and a differential in a third. There were failed window regulators, check engine lights, prematurely worn suspension components, and phantom tire pressure monitors. And my Mercedes G-Wagen suffered throttle response problems until I realized it was rusty enough to be a Civil War-era shipwreck. But they were great when they were working, right?
Unfortunately, this is the greatest problem with German cars: they're never working. Oh, sure, they have relatively few problems for the first few years of ownership. (Technically defined as: "Right up until the Thursday after the warranty expires.") But even then, you're still losing an insane amount of money in depreciation. And once the depreciation curve starts to flatten, the problems start to crop up, which means you can't safely own a German car for more than an afternoon without spending as much money as round trip airfare to Bermuda.
Of course, my own anecdotal experiences aren't my only evidence here. We also have years of JD Power Long Term Dependability Studies, which routinely place American or Japanese cars into the top dependability spots, while German cars go into entirely different categories, such as Broke Down on the Way to Test Facility.
The main problem, as I see it, is that the Germans are just too obsessed with stuffing all sorts of newfangled gizmos into their cars. This is largely because no one questions the prowess of German engineering; they're still the best at that. So they continue to show their engineering dominance by creating all sorts of crazy gadgets and sticking them in the cars; stuff that no one wants, such as cooled gloveboxes, and rear armrest refrigerators, and those little tray tables that fold down, presumably to allow people riding in the back of an Audi A8 to do some cocaine.
For a better example of this, I turn to the first-generation Audi Allroad, which was an all-wheel drive station wagon that went on sale here in America during the fall of 2000.
While most companies would be content with simply building an all-wheel drive station wagon, Audi couldn't do just that. They had to do more. They couldn't just have normal suspension, for instance. They had to have adjustable suspension that would raise and lower to allow Connecticut families to traverse grass parking lots at lacrosse games. They couldn't just have a typical automatic transmission; it had to offer manual shifting capability. And they couldn't just have a regular V6 engine – they had to add two turbochargers.
The result, as I'm sure you can imagine, is that the suspension failed, the transmissions went bad, and every single remaining V6 Allroad is currently leaking oil through its turbochargers, except the ones that are up on blocks because of bad suspension and a blown transmission. All of this, by the way, was in addition to your usual set of Audi problems, such as – this one actually happened to me – turn signals that don't blink, but rather stay lit when you press the lever.
For this reason, I have taken to measuring automotive reliability on a scale I've dubbed the "Audi Allroad Scale Of Unreliability," which rates cars based on how close they are to the original Audi Allroad in terms of potential for random four-figure maintenance bills. For example: the Lexus ES300 is pretty low on the Audi Allroad Scale Of Unreliability. Whereas a vehicle made entirely by chimpanzees provided with random car parts would be almost as bad as the Allroad. Maybe even worse if the chimpanzees are German.
@DougDeMuro is the author of Plays With Cars. He owned an E63 AMG wagon and once tried to evade police at the Tail of the Dragon using a pontoon boat. (It didn't work.) He worked as a manager for Porsche Cars North America before quitting to become a writer, largely because it meant he no longer had to wear pants. Also, he wrote this entire bio himself in the third person.

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Lovely week ahead, don't get sunburn, pick some flowers and don't miss this week's highlights: A little bit of La Boheme and Janette Geri!
Monday 12th April
9-close Film Night - 4 eyed monsters
Digital media is simply a new language they fell in love through... http://www.foureyedmonsters.com/trailer/
Tuesday 13th April
2.30pm & 3.30 pm (two 20 min performances) A little bit of La Boheme – a specially written version of Puccini's La Boheme, with a Scottish opera singer, musicians, colourful illustrations and a storyteller to bring it all to life
8pm-close Volunteer party
Volunteer and you shall be rewarded. Remember, the theme is Facial Hair!
Wednesday 14th April
7 -8pm Gramophone Hour
78's from 7 to 8
Friday 16th April
9-close The Thirteen Seven
Soaring choruses enfused with crunching riffs and searing guitar leads... the alternative-experimental rock band is back for another live session!myspace.com/thirteenseven137
Saturday 17th April
7-8.30 Ramblin' Jack
Presents poetry and rock'n'roll
9-close Janette Geri
Earthy, eclectic, sensual, original, Janette Geri is one of Australia's finest singers, a serious guitar player, and an acclaimed songwriter
Sunday 18th April
1-5pm Free shop
Bring your own or just grab some stuff looking for a new owner
5-6.30 Accordion songs
A lovely evening with harmonious sounds and warm voices
All workshops are FREE and open to everybody. Share skills – create a workshop. Contact: email@example.com
Mon, 11-12am: Chi Kung lesson (Hall)
Mon, 12am-1pm: Self Defense (beginners) (Hall)
Tue, 7-9pm: Origami Workshop (Action room)
Tue, 7-9.30pm: Forest Choir (Hall)
Wed, 2pm: Gaelic workshop (Cafe)
Thu, 11-12am: Chi Kung lesson (Hall)
Fri, 5-6pm: Self Defense for beginners (Hall)
Sun, 7.30pm: Forest Drama Group (Hall)
Sun, 1-4pm: A Scrappage Salvage (Hall)
Sun, 1-4pm: Bike Café (Hall)
5-18th April
New Paintings by Robert Euman
Old Hat books
Free Radical Book & Hat Library
Mondays - Wednesdays – Saturdays: 4pm – 8pm
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Synthesis, Characterization of Schiff Bases and Biological Activities of Their Transition Metal Complexes-Review
D.T. Sakhare,
D.T. Sakhare,
13 May 2020
Abstract :
: Schiff bases are versatile ligands which are synthesized from the condensation of primary amines with carbonyl groups. These compounds are very important in medicinal and pharmaceutical fields because of their wide spectrum of biological activities. Most of them show biological activities such as antibacterial, antifungal as well as antitumor activity. Transition metal complexes derived from the Schiff base ligands with biological activity have been widely studied. This summarizes the synthesis and biological activities of Schiff bases and its transition complexes.
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Puppy mills
Many people don't realize that when they buy a dog from a pet store or on the Internet, that dog most likely came from a puppy mill, a "factory farm" for dogs. In puppy mills, dogs live in small cages, often in the minimum legal size allowed (only six inches larger than the dog on all sides) and female dogs are bred as frequently as possible.
Life in a puppy mill is no life for our best friends. Even though more and more Americans are taking a stand against them, the U.S. still has about 10,000 puppy mills. Together, we can take a stand against puppy mills and make them a thing of the past.
For more about life in a puppy mill, check out this eye-opening video.
Why puppy mills still exist
Puppy mills have been inhumanely breeding and selling dogs for decades. Although the federal government regulates most breeders who sell puppies online and to pet stores, the minimal standards imposed on breeders don't promote responsible breeding or ensure healthy puppies. For example, it's legal for licensed breeders to own 1,000 or more dogs, keep them in very small cages for their entire lives and breed them as often as possible.
The standards set by the government aren't meant to ensure that the dogs have the good lives they deserve; they only require the bare minimum of care. Plus, there are only a few inspectors in each state for hundreds – sometimes thousands – of licensed breeding facilities.
Best Friends' puppy mill initiatives
Through Best Friends' puppy mill initiatives, we are working to convince pet stores to offer pets for adoption instead of selling mill-bred pets, educate consumers about puppy mills, and create and lobby for humane legislation. Together, we're making an impact and saving lives. Join us and help bring about a time when every dog can feel safe, happy and loved.
Please watch and share this video!
Where are puppy mill dogs sold?
Pet stores: Nearly all pet stores that sell puppies are supplied by mills. More and more communities are banning the sale of mill-bred pets in stores, but many Americans are still unaware of the connection between pet stores and puppy mills.
Which pet stores sell puppies supplied by puppy mills? Nearly 100 percent.
Estimated number of puppy mills in the U.S. that supply to pet stores or sell online: 10,000
Websites: Just like pet stores, most websites that sell dogs are selling mill-bred pets, and most of these sites market the puppies as well-bred and lovingly raised. No matter how convincing a website is, though, never buy a pet online.
Classified ads: For decades, classifieds have been the first place that puppy buyers go to look for a new pet. Irresponsible breeders tap into this market easily by placing classified ads on websites like Craigslist. Please beware of any ads that list several breeds for sale. And if the breeder won't let you see where the dogs and puppies live, please don't buy the puppy.
How to fight puppy mills
- Don't buy dogs from pet stores or on the Internet. Please adopt instead.
- Spread the word: Teach others about puppy mills.
- Choose adoption.
Around 625,000 dogs and cats are killed in U.S. shelters annually, simply because they don't have homes. When you adopt, you're not only refusing to support puppy mills, you're saving a life and giving an animal in need the second chance he or she deserves.
If you're looking for a healthy, loving pet, you're in luck. Many can readily be found in shelters and rescue groups around the country.
It is estimated that up to 25 percent of dogs looking for homes through shelters and rescue groups are purebred.
Types of pets found in shelters and rescue groups:
Young, purebred, old, house-trained, mixed-breed, adorable, well-mannered, puppies, healthy, kittens
No matter what type of pet you're looking for, a shelter or rescue organization is the place to go.
By choosing adoption, you're taking a stand against the puppy mill industry.
Contact information: firstname.lastname@example.com
Fight puppy mills, and save lives today. Join Best Friends Animal Society in putting an end to large-scale dog breeding operations.


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He's On the Waiting List
I am so confused. Yesterday, when I talked to the lady from the preschool she said she had a spot held for Jamie and that we needed to get the paperwork to her by today. When Matt took the paperwork to the school they said that they would put Jamie on the waiting list. I don't know what's going on.


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This guidebook includes tales of the native culture, from the pornographic cinemas in Lahore to catching crabs in Karachi. Details on excursion by jeep or steam train up the Khyber Pass are included, as are critical listings of places to stay.Lindsay Brown is the author of 'Lonely Planet Pakistan & the Karakoram Highway (Country Travel Guide)', published 2008 under ISBN 9781741045420 and ISBN 1741045428.[read more]
You can find lots of answers to common customer questions in our FAQs
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Another opening, another show!
Well, I attended the WDYTYALive family history show in London on Friday 26th February. A busy and tiring day, but I managed to visit most of the stalls I had prepared questions for, and received welcome advice, before my first day's seminar at 12:30am. The remainder I visited dodging between the seminar schedules.
The actor and historian, and UK face of Ancestry.co.uk, Tony Robinson, presented The Journey of a Record at the Ancestry Academy, and visitors through the day could hear beginner, intermediate and advanced talks, with the main advanced presentation being given by genealogy and history expert Dr. Nick Barratt (personally, I felt a little too much cross-over between content of the latter two that I visited).
Gill Blanchard's talk on Norfolk ancestors was welcome, since I may have to trace there (as confirmed by a visit to the Norfolk FHS stall).
The talk on the 1910 Valuation Survey ('Lloyd George's Domesday') given by Peter Park was 'different' but useful, amongst other things highlighting how the occupier of property is not necessarily the owner, and that occupation could change a lot within a short few years.
All-in-all, another worthwhile visit, and the extra CDs I bought from KFHS have already this weekend yielded tree expansion and clarification around Birchington, Chartham and Challock!


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I've noticed that Purex is often coming out with new formulas, scents, or ways to do laundry. I like that they stay on top of things. The newest, Purex PowerShot detergent, has the only bottle that measures the right amount of detergent every time. It's easy to use - just Flip. Dose. Done!
To celebrate the release of the NEW Purex® PowerShot™ detergent, Purex is hosting an amazing sweepstakes, the Purex PowerShot Coming Soon Sweepstakes. There will be three grand prize winners of a Whirlpool washer and dryer set. 300 second-place winners will receive a bottle of PowerShot. Sweepstakes ends March 31, 2015.
One person will win two free product coupons for Purex PowerShot Detergent.
*This is a Rafflecopter giveaway open to residents of the USA.*
a Rafflecopter giveaway


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We don't have this item available for sale at the moment.
New Phyrexia, the third set in the Scars block (released May 13, 2011) brings the story of the war in Mirrodin to an end with the defeat of the Mirrans and the plane coming into the control of the Phyrexians. This defeat is reflected in a reversal of the ratio of Phyrexian to Mirran cards that was present in the first set. Also, mechanics such as Proliferate and Infect are freed from their usual color restrictions showing that Phyrexian influence is everywhere now. The basic land cards in the set also had artwork to showcase the takeover by the Phyrexians.
The inclusion of Phyrexian mana made this one of the most interesting sets to date in draft formats and Standard play. All colors suddenly had access to Counter Spell (Mental Misstep) and draw power (Tezzeret's Gambit). This lead to some of the most creative and innovative decks seen.
Keep an eye out for some truly exceptional cards like Karn the Liberated, Act of Aggression, Beast Within, Sword of War and Peace, Batterskull, and Surgical Extraction just to name a few.
There are 175 black-bordered cards in the third set of the Scars of Mirrodin Block.
36 packs per box, 15 cards per pack
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Fancy a read from your local area? The books below focus on the history, culture, society, challenges and triumphs of the Camden LGA. Why not get acquainted with your local area a little more and try one of these great reads available at Camden and Narellan branches.
1001 Life Story Questions by Bob Mitchell
A History of St. Claire by S.J. Tazewell
A Glimpse of Cawdor by John W. Burge
78 Fighter Squadron, RAAF by L.A.C. Burns
A History of Nepean and District Street Names by Lorna Parr
A Treasury of Australian Folklore by Bill Beatty
The Age of Macquarie by James Broadbent and Joy Hughes
Australia will be there: Growing Up in the First World War
Belgenny Farm: Birthplace of Australian Agriculture by Richard Wood
The Best of Back Then by John Wrigley


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Burdick's European-inspired gourmet chocolates are made with fresh, natural ingredients with no artificial colors, flavors, or preservatives. Combining Swiss know-how, French gastronomical thoughtfulness, and American imagination, each unique bonbon is hand-cooked, hand-cut or -shaped, hand-garnished, and hand-packed.
Large: 6.5" x 4" x 2.5"
Medium: 4" x 4" x 2.25"
Small: 4" x 4" x 1.5"
Petite: 4 x 3" x 1.5"
Large: 360 g | 12.7 oz
Medium: 200 g | 7 oz
Small: 100 g | 3.5 oz
Petite: 79 g | 2.4 oz
Store in a cool, dry place.
We suggest enjoying within 2 weeks.
Our chocolates are naturally gluten-free.
Ingredients: Dark chocolate, milk chocolate, gianduja, cocoa powder, ginger, almonds, cashews, sesame, eggs, Macallan whisky, pistachios, Chartreuse, lime, lemongrass, white chocolate, vodka, lavender, chamomile, nutmeg, cocoa nibs, raspberries, butter, cherries, kirsch, figs, raisins, Earl Grey tea, corn flakes, Poire Williams, fennel seed, saffron, orange juice, espresso, cinnamon, port wine, limoncello, cardamom, cream, fleur de sel, vanilla bean, anise seed, apricots, honey, Herbes de Provence, rum, cognac, peppercorns, milk, mango, soy lecithin
ALLERGENS: Dairy, Soy, Eggs, Tree Nuts
Our products are prepared in kitchens where nuts are used, and where nut traces may be present.
Please call 800.229.2419 if you have any questions.
L.A. Burdick Chocolate tries to minimize shipping costs for our customers. We do not profit from shipping charges. Rates are based on the total size and weight of product(s) being shipped.
How and When We Ship
Orders received prior to 3:00pm EST can be shipped the same day unless a specific future delivery date has been requested. Orders received after 3:00pm EST or during the weekend or on a holiday will be processed on the next business day. We do not ship over the weekend; selecting Friday as a ship date will show a Saturday Delivery shipping option (with a $15 Saturday delivery surcharge).
We cannot ship to a P.O. Box. An accurate street address with applicable suite or apartment number and/or business name, and phone number is required to ensure proper delivery.
Additional Information & Tips
Shipping overnight is always recommended when product may be compromised due to weather and location.
Our Signature Wood Box Bonbon Assortments are tied with a festive holiday ribbon and stamped with a silver menorah wax seal. The Large Assortment contains 61 pieces, including 2 Signature Chocolate Mice. The Medium size contains 37 pieces, including 2 Signature Chocolate Mice. The Small contains 18 pieces, including 1 Signature Chocolate Mouse. The Petite contains 11 pieces, including 1 Signature Chocolate Mouse.
All our gourmet chocolates and confections are made with only natural ingredients and without preservatives, artificial colors and flavors, extracts, or essences.
Pre-order now to ship later. Shipping November 30 - December 18, 2020.


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Buggy Adventure
From 70 Euro per Adult / minimum 2 persons
Experience the thrills of riding a buggy through Berber rural areas and pre-Saharan terrain. Discover the spectacular Sidi Toual beach, and complete this experience with a delicious Berber-style breakfast.
|Your adventure begins with hotel pick-up, followed by a drive South of Agadir to the Berber village of Takkat, to meet your guide. After an introduction to on- and off-road buggy driving techniques, a briefing, and a practical advice session, you are ready to hop on your buggy and begin driving.Pass through the Berber villages of Benguemoud and Errouaiss, through farmlands, as well as through argan and fig forests; you may even meet nomadic shepherds. Next, weave your way through sunny sand dunes and head to the beautiful secluded beach of Sidi Toual. On the return drive, stop for a homemade Berber-style breakfast: enjoy mint tea, Argan oil, Amlou (Moroccan dip), honey, and homemade bread. Once you've recharged your batteries, continue to Takkat to meet your driver, who takes you back to your Agadir hotel.Inclusions :
Departure time and location:
Return time and location:
Participant restrictions:
Important booking tip:


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If yer like me, your probably amassing a collection of mp3s of various genres from
various sources such as the Internet, Library CDs, and (of course) bought CDs in
the hopes of someday replacing them with high quality versions. You know, better
to have a sound file than just a name...
You might notice that the sound from these sources is generally pretty mid-tone,
that is, is very (what some people call "muddy") then other's call it "warm", but
IMO, it's just plain muted.
Well, it's a fairly simple process to fix this problem, you just need a wav editor
and an EQ plug-in (i use Audi126).
But how to manage the EQ levels? Most people play with the EQ and really manage
to royally F-up the sound....
Well, I developed a theory that seems to make this audio processing a bit easier.
I call it Ratio EQing. Basically it's the same as regular EQing except you maintain
a "ratio" between frequency band volume levels.
I detail it in this post:
http://forum.audacityteam.org/viewtopic ... 28&t=62815
BTW, as an added bonus to you 808 State fans (and enemies), I've actually been
using something like (starting at 25 hz):
Something about maintaining a ratio between frequency volume levels manages
to keep the volume levels of the final mixes consistant while reducing that mid-tone-
frequency "jack-up" and clearing up the the upper frequencies.
Also, I sometimes just use 0 for 25hz and 16000hz, prefering to use these
volumes for bass/treble boosting...
I used this on an mp3 copy of the Trashman's "Cosmotrash" which I first heard
a few years back after downloading an 808 Radio show hosted by the sometimes
brilliant Robert "Smith" Carlyle and it sounds much better.
You know, everyone plans to upgrade their collections in the future, but why not
have an mp3 that at least sounds closer to how it should?
TIP: Cleaning up MP3s
Discuss musical topics that are not directly 808 State related.
Moderators: Pob, markus, nickking, Ancodia
Post Reply
2 posts • Page 1 of 1
Re: TIP: Cleaning up MP3s
Back in the late 1990s or early 2000s I ran a Dave Clarke set streaming in Real Audio through an Aphex Aural Exiter and recorded it back into a Mac. It actually sounded pretty good in a lo-fi sort of way. The highs when he was working with effects would hurt your ears when cranked up loud and the low end had rumbling bass like you were part of an earhquake. It was fun to play while driving.
Post Reply
2 posts • Page 1 of 1


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How the Galileo atomic clocks work
For a satellite navigation system to work correctly, it is necessary that the signals broadcast by the satellites are transmitted synchronously. In order to achieve this, the satellites carry very stable clocks.
The Galileo satellites carry two types of clocks: rubidium atomic frequency standards and passive hydrogen masers. The stability of the rubidium clock is so good that it would lose only three seconds in one million years, while the passive hydrogen maser is even more stable and it would lose only one second in three million years. However this kind of stability is really needed, since an error of only a few nanoseconds (billionths of a second) on the Galileo measurements would produce a positioning error of metres which would not be acceptable.
An atomic clock works like a conventional clock but the time-base of the clock, instead of being an oscillating mass as in a pendulum clock, is based on the properties of atoms when transitioning between different energy states.
An atom, when excited by an external energy source, goes to a higher energy state. Then, from this state, it goes to a lower energy state. In this transition, the atom releases energy at a very precise frequency which is characteristic of the type of atom. This is like a signature for the type of material used. All that is needed for making a good clock is a way of detecting this frequency and using it as an input to a counter. This is the principle behind an atomic clock.
The transitions between energy states can take place by releasing or absorbing energy at optical or microwave frequencies. An atomic second corresponds to 9 192 631 700 counts of the frequency of the energy detected in the transition of the Cesium 133 isotope when exposed to suitable excitation.
Rubidium clock
The Galileo rubidium clock is made of an atomic resonator and its associated control electronics. Inside the atomic resonator there is a rubidium vapour cell. The atoms are kept in a gaseous state at high temperature. In order to initiate the resonance, the atoms of the cell are excited to a higher state by the light of a rubidium discharge lamp located in one end of the atomic resonator. At the other end of the resonator there is a photodiode which detects the amount of light that passes through the cell.
Following the excitation, the atoms decay to a lower state. From this state, the atoms are excited back to an intermediate level by injecting microwave energy in the resonator at a given frequency. Transition to the intermediate level only occurs if the frequency corresponds exactly to the one associated with this transition. When the atoms are in the intermediate state, the absorption of light is at a maximum.
The output of the photodiode is connected to control circuitry which adjusts the microwave frequency. The correct frequency is maintained by tuning the microwave source to obtain maximum light absorption. The resonance is maintained by the energy from the rubidium lamp, since the atoms in the intermediate state are again excited to the higher state and then decay to the lower state, from which the whole process starts again.
Hydrogen maser clock
The Galileo passive hydrogen maser clock is also made of an atomic resonator and its associated control electronics. In this clock, a small storage bottle supplies molecular hydrogen to a gas discharge bulb. Here molecules of hydrogen are dissociated into atomic hydrogen. After dissociation, the atoms enter a resonance cavity by passing through a collimator and a magnetic state selector. This magnetic state selector is used to let only atoms of the desired energy level enter a resonant cavity. Here the atoms are confined in a quartz storage bulb. Once in this storage bulb the hydrogen atoms tend to return to their 'fundamental' energy state, emitting a microwave frequency as they do so.
This frequency is detected by an interrogation circuit which locks an external signal to the 'natural' transition of the hydrogen atoms. Locking occurs when the injected frequency is the same as the resonant frequency of the atoms; this corresponds to an amplification of the microwave signal.
The resonant frequency of the microwave cavity is approximately 1.420 GHz. The clock's electronics includes circuitry for the control of the frequency plus the thermal control system to maintain the resonant cavity at the correct temperature.
The atomic resonator is very sensitive to the external environment (for example, magnetic field). Great care is required to keep environmental disturbances small so that the full performance potential of these sophisticated clocks can be realized.


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I love bringing little touches of nature into my home… a dried seedhead here, a pheasant feather there… they help to soften up a minimal room and bring a tiny bit of the outdoors in.
This small New York apartment belongs to prop stylist Rebecca Bartoshesky and I really admire her style. She has just the right amount of artistic clutter and some really nice ideas for using natural elements and found objects in a decorative yet simple way.
Look closely and you'll see little natural touches in evey single corner of this home. Not so much that it looks like a museum (remember this Victorian collector's cottage?) but just enough to bring in the subtle earthy tones and rustic textures that only real shells, plants and feathers can add.
If you like this look, choose natural fibre fabrics as Rebecca has – raw linen or material coloured with vegetable dyes are ideal as their muted tones are just right for adding colour in a way that doesn't jar. Dyeworks specialises in selling naturally-dyed fabrics, or Sania Pell wrote this lovely post explaining how to make your own fabric dyes from berries, vegetables and spices.
{Photographs Pippa Drummond / Styling Rebecca Bartoshesky for Sight Unseen}
For those of us that remember 1990s 'bohemian chic' the idea of tie dying is a little bit scary, but there's no denying it's making a come-back. If proper tie-dye like Rebecca's bedspread sends you running for cover, dip dying is just as easy and is less likely to make your home look like a hippy hangout. I went to a trend forecasting presentation last week and ombre is going to be sticking around for at least another two seasons, so there's still time if you haven't yet succumbed!
This beautiful apartment was origianally featured on the lovely Sight Unseen blog where you'll find lots more photos and pretty details of Rebecca's home – find the post here.


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Music for Everyone
25 Elm Place, 5th Floor
Brooklyn, 11201
Time: 3:00 PM - 5:00 PM
The Music for Everyone class is for anyone interested in learning music reading by sight, no matter what instrument you're partial to! Musical notes are the same for all instruments.
Content: Music scales, signature, clefs, theory, hands-on piano practice, and lessons. Designed for adult beginners and intermediates; supplies will be provided, free of charge.
Instructor: Julia Yepez
Open to adults with physical disabilities and seniors living in Brooklyn, Bronx, Queens and Manhattan. Space is limited.
For more information or to sign up: Contact Latricia James at (718) 907-1622.
Members: Transportation is NOT provided, but mass transit use may be reimbursed. Please speak to your care manager for more information.


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American genealogy software, like our movies and music, has garnered many fans overseas. But foreign programs remain popular abroad, and it's useful to see how they stack up to our homegrown products. One of those foreign programs, Embla Family Treasures, was originally developed in the United States, but later sold to a Norwegian company. Now the top-selling genealogy software in Norway, Family Treasures will run and print reports in English and Norwegian; Danish and Swedish versions are in the works. Aside from its multilingual capabilities, Family Treasures stands out for its novel user interface and an unusual pricing plan.
Sparkling setting
Navigating through your family's generations, editing data and documenting sources work differently in Family Treasures than in most other genealogy software. A large panel on the left side of the screen displays information in the Tree Editor, Member Editor and Family Editor (called pedigree, individual and family views in other programs). In the Tree Editor, you can view dates and places of birth and death for each person; the Member Editor has a handy chronological listing of all the events in a person's life. Instead of the pull-down menus typical of most Windows programs, Family Treasures makes functions easily accessible in a small panel on the right side of the screen. The program also uses an unusual — but handy — drag-and-drop system. To link a source to an event, just drag the source to the event listing with your mouse. You'll need the Power Pack add-on (see below) to easily reuse source citations.
GEM dandy
Family Treasures' unusual pricing plan also sets it apart from other genealogy software. You can download the core program with all the basic functions for free at <www.embla.us>, or order it on a $10 CD-ROM (visit the Web site or call 716-792-9679). Embla packages special features separately in Genealogy Extension Modules (GEMs), priced from $5 to $15. GEMs provide tools for producing colorful photo family trees, birthday and wedding "plaques" suitable for framing, and a genealogy Web site. Instead of buying a bloated program with multiple features you'll never use, you pay for only what you really want.
The $9 Power Pack, an essential GEM for most users, lets you attach more than one photo to individual and family records, and add to-do notes. The Family Treasures Gift Pack CD-ROM includes the main program as well as the Power Pack, Hourglass Charts, Calendar and Colorful Reports GEMs, all for $29. Or you can opt for a one-year membership that gives you $100 worth of GEM points to spend on the GEMs of your choice. At $49 a year ($35 for existing users), a membership saves you 50 percent or more off the normal GEM prices. Updates to the core program are always free.
Rough around the edges
With the GEM add-ons, Family Treasures provides all the basic functions you need in genealogy software. But some features need improvement. The most-recent version, 5.1, lacks call-number and actual-text fields, so if you import a GEDCOM file (the universal family tree file format) created with another program, you'll lose that source information. In the next update, however, Embla plans to include a transcript field to hold the actual text of a source document. Family Treasures' attractive Ancestor Tree Chart shows four generations with pictures, and you can customize it with your choice of colors and fonts. GEM add-on programs expand the range of graphical charts, but family group sheets sometimes don't include all events and sources. Book-format reports use the Henry numbering system instead of the more popular New England Historical and Genealogical Register and Modified Register formats. And the program improperly formats footnotes, which remain unnumbered.
Although Family Treasures has some rough edges, Embla's continually improving the free core program and developing new add-ons. The unique user interface and unconventional pricing plan give you a real alternative to American programs. And if you'd like to print charts for relatives in Scandinavia, Family Treasures makes it easy. The program requires Windows 98 or higher.


text:
Feldman Shepherd
Trial lawyers for the most important things in life
No results found. Please try modifying your search.
Leslie has chosen to fundraise with HelpHOPELive in part because HelpHOPELive assures fiscal accountability of funds raised and tax deductibility for donors. Donors can be sure that funds donated will be used only to pay or reimburse medically-related expenses. For more information, please contact HelpHOPELive at 800.642.8399.
Thanks for your support!
Make checks payable to:
Help Hope Live
Note in memo:
In honor of Judy Cunningham
Mail to:
Help Hope Live
2 Radnor Corporate Center
Suite 100
100 Matsonford Road
Radnor, PA 19087


text:
City officials announced today that a piece of the America's Cup is coming to Alameda: One of the eight teams competing in the sailing regatta is setting up shop at Alameda Point.
Artemis Racing, which represents the Royal Swedish Yacht Club and is the challenger of record for the Cup, is leasing a 110,000-square-foot former airplane hangar at Alameda Point. The team has signed a three-month lease - enough to get them through the World Series races in San Francisco this summer - with an option to remain for up to a year, Alameda Community Development Director Lori Taylor said.
"Alameda offers convenient shoreline water access to our racing grounds in San Francisco Bay immediately next to large industrial warehouse space. It is a turn-key option which will allow us to operate efficiently and immediately in 2012," Artemis Racing's chief executive officer, Paul Cayard, said. "We all look forward to settling in for this season and making the most of the facility."
The city has also been designated as an official launching point for accessing the races, with expanded service from its ferry terminals.
City officials said they're thrilled the 70-person Artemis team has chosen to make Alameda their home away from home, and they touted the array of services, maritime and otherwise, at the team's disposal.
"We are honored that some of the most elite sailors in the world, commanding the fastest sailing vessels, have chosen to make Alameda their home port," Mayor Marie Gilmore said. "We enthusiastically welcome the 70-member Artemis Team and their families to our community."
The city has an America's Cup committee that has been working to promote Alameda as a destination for teams and visitors, and the leader of that committee expressed his excitement about the team's arrival.
"Our community is ecstatic about Artemis being here," said Christopher Seiwald, Chair of the City's Ad Hoc Committee for the America's Cup. "It is great news for our local economy that we will be hosting these magnificent catamarans and their crews right here in Alameda."
The 34th America's Cup race, which is headed to San Francisco in 2013, is expected to generate $1 billion in economic benefits for that city and draw millions of fans and spectators. Event organizers are hoping the Bay will prove to be a more media- and spectator-friendly location that increases the visibility of the Cup and the sport.
The Cup has been billed as the world's most prestigious sailing event.
The team, skippered by American Terry Hutchinson, took the match racing championship title in the latest America's Cup World Series event, which concluded Sunday in Venice. Artemis Racing is in third place in World Series racing so far, holding the top position for match racing and fourth place for fleet racing.
The team became the Challenger of Record in the regatta after an Italian team, Mascalzone Latino Audi, dropped out.
The next World Series event takes place from June 26 to July 1 in Newport, Rhode Island. The Cup comes to San Francisco in late August, when World Series racing takes place, and continues there in October during Fleet Week.
Teams will race for the Louis Vuitton Cup from July 4, 2013 to September 1, 2013, with the winner earning the sole right to challenge defending America's Cup champion ORACLE Racing for the title.
More information:
America's Cup Ad Hoc committee
Al Wright
Wed, May 23, 2012
I watched some of the Venice
I watched some of the Venice race on channel 41; this is going to be fun!
Fri, May 25, 2012
Brilliant news. Way to work
Brilliant news. Way to work it Alameda.


text: Here's a very funny clip from the Colbert Report where Jeff Goldblum is reportedly dead based on Twitter posts. The funniest thing about this is that it really happened (the twitter posts) and reported as fact on the Australian Today Show. His death is to have happened on the same day as Michael Jackson's death and this clip includes the Australian Today Show segment.


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Increasingly our understanding of IBS is that it is a heterogeneous disorder – that is, multiple factors contribute to the well defined symptoms of the disorder. One of these suspected underlying dysfunctions involves serotonin, which is a neurotransmitter or messenger to nerves.
Most serotonin in the body is in cells that line the gut where it senses what is going on and through receptors signals nerves that stimulate a response. The serotonin must then be reabsorbed (a process called re-uptake) into cells. This process appears to be disrupted in people with IBS.
Serotonin and SERT
How does serotonin affect gut function? An interview with Gary M. Mawe, PhD, Professor of Anatomy and Neurobiology, University of Vermont, Burlington, VT. Dr. Mawe is a basic scientist.


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SAN DIEGO, Sept. 26, 2013 /PRNewswire/ -- Halozyme Therapeutics, Inc. (NASDAQ: HALO) today announced that the commercial launch of Herceptin® SC in Europe has triggered a $10 million milestone payment to Halozyme under the License and Collaboration Agreement between Halozyme and Roche. This time-saving subcutaneous formulation of Herceptin (trastuzumab) using Halozyme's recombinant human hyaluronidase (rHuPH20) received marketing authorization from the European Commission on August 28, 2013 for the treatment of patients with HER2-positive breast cancer and was launched upon approval. Herceptin SC reduces treatment times and enhances convenience compared to the standard intravenous (IV) form.
(Logo: http://photos.prnewswire.com/prnh/20100302/LA63139LOGO)
"With pricing on par with the intravenous formulation, Herceptin SC represents a compelling treatment alternative for breast cancer patients in Europe, and we congratulate Roche on making this time-saving therapy available to patients in Europe so quickly," said Gregory I. Frost, Ph.D., President and Chief Executive Officer of Halozyme. "This will be the third commercial product using our rHuPH20 enzyme and represents a significant achievement for our technology and company as a whole."
About Breast Cancer
Breast cancer is the most common cancer among women worldwide.1 Each year, about 1.4 million new cases of breast cancer are diagnosed worldwide, and over 450,000 women will die of the disease annually.1 In HER2-positive breast cancer, increased quantities of the human epidermal growth factor receptor 2 (HER2) are present on the surface of the tumor cells. This is known as "HER2 positivity" and affects approximately 15% to 20% of women with breast cancer.2 HER2-positive cancer is a particularly aggressive form of breast cancer.3
Halozyme-Roche Collaboration
In December 2006, Halozyme entered into an agreement with Roche to apply Halozyme's proprietary Enhanze™ technology to Roche's biological therapeutic compounds. To date, Roche has elected to develop and commercialize products using rHuPH20 with a total of five exclusive targets, and Roche retains the option to apply rHuPH20 to three additional targets through the payment of annual license maintenance fees. In February 2011, Roche began a Phase 3 registration trial of subcutaneous (SC) MabThera (rituximab), an anticancer biologic, in patients with non-Hodgkin's lymphoma (NHL) and chronic lymphocytic leukemia (CLL) and submitted a line extension application to the European Medicines Agency for MabThera SC in December 2012. Subject to the successful achievement of clinical, regulatory, and sales events, Roche will pay Halozyme additional milestones as well as royalties on product sales for Herceptin SC, MabThera SC and other product candidates developed and commercialized under the agreement.
About Halozyme
Halozyme Therapeutics is a biopharmaceutical company dedicated to developing and commercializing innovative products that advance patient care. With a diversified portfolio of enzymes that target the extracellular matrix, the company's research focuses primarily on a family of human enzymes, known as hyaluronidases, which increase the absorption and dispersion of biologics, drugs and fluids. Halozyme's pipeline addresses therapeutic areas, including diabetes, oncology and dermatology that have significant unmet medical need. The company markets Hylenex® recombinant (hyaluronidase human injection) and has partnerships with Roche, Pfizer, Baxter, and Intrexon. Halozyme is headquartered in San Diego, CA. For more information on how we are innovating, please visit our corporate website at www.halozyme.com.
Safe Harbor Statement
This release includes forward-looking statements such as the potential benefits of Herceptin SC to patients, and the possible receipt by Halozyme of future milestones and royalties under the Halozyme-Roche collaboration agreement. The statements are based on assumptions about many important factors, including the following, which could cause actual results to differ materially from those in the forward-looking statements: the satisfaction of regulatory and other requirements; actions of regulatory bodies and other governmental authorities; unexpected adverse events; changes in laws and regulations; competitive conditions; and other risks identified in Halozyme's Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on August 7, 2013. Halozyme does not undertake to update its forward-looking statements.
1Ferlay J, Shin HR, Bray F, Forman D, Mathers C and Parkin DM GLOBOCAN 2008, Cancer Incidence and Mortality Worldwide: IARC Cancer Base No. 10 [Internet]. Lyon, France: International Agency for Research on Cancer; 2010. Available from: http://globocan.iarc.fr.
2Wolff A.C et al. American Society of Clinical Oncology/ College of American Pathologists Guideline Recommendations for Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer. Arch Pathol Lab Med—Vol 131, January 2007.
3Slamon D et al. Adjuvant Trastuzumab in HER2-Positive Breast Cancer. N Engl J Med 2011; 365:1273-83.
Investor Contact:
David Ramsay
Halozyme Therapeutics
Media Contact:
Nurha Hindi
Hill+Knowlton Strategies
|SOURCE Halozyme Therapeutics, Inc.
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University of Arizona; USDA. Animal and Plant Health Inspection Service; Arizona Department of Agriculture.
This list of the most serious biotic pests and pathogens is maintained by the State (Arizona Department of Agriculture) and Federal (USDA) regulatory agents. Their goal is to prevent the introduction and/or spread of these pests/pathogens in our state.


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Printed Memorials
Waterfall 8-Sided Graduated Bottom Funeral Program Design & Print (Pack of 25)
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- Package of 25 programs; $3.95 ea. Ships the next day after your final approval of proof. Can ship same day if proof approval is given before 12noon CST.
An absolutely stunning landscape with the gracefulness of an outdoor waterfall flowing down the rocky landscape. Soft lighting projects through the lush trees for a great scenic and picturesque backdrop for any loved one. Nobody does it better than us! Our work stands on its own and will highlight your loved one as they deserve in this high quality, professionally designed layout. This wonderful 8-sided program is available in the traditional letter size or 2 larger sizes which will accommodate more room in Legal and Tabloid graduated bottom layouts.
We remove your photo's background and merge it seamlessly into our design for a truly custom layout! Completed programs and/or cards are folded, shrink wrapped, shipped FEDEX (1, 2, or 3 day express shipment) right to your door and ready for distribution. Orders are shipped the next business day if approved program is ordered before 5 pm. Monday - Friday.
Complete Full Service, All-Inclusive Professional Design & Printing; Package of 25 graduated bottom fold funeral programs
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AP Sports Writer FISHERS, Ind. (AP) - Right in the middle of the Walk of Fame at Hamilton Southeastern High School - not far from the championship honors for mock trials, swimming and girl's golf - are two 8-by-13-inch photos. One shows a smiling two-time, all-state football player and the other an unassuming two-time, all-state basketball player.
Same kid, smiling or not. And it has been quite a ride for Gary Harris these past few years.
In just 12 months, Harris has gone from a 17-year-old, two-sport preps standout to a bona fide college basketball star. The former Indiana Mr. Basketball is the Big Ten freshman of the year, and he will play a big role this week in determining whether Michigan State will advance to the Final Four.
It's hard for anyone in this northern Indianapolis suburb, including the Harrises, to fathom. There is also talk of the June NBA draft floating around, too.
'Surreal,' said Harris' father, Gary. 'A lot has transpired in the last 12 months and it's just so exciting to be living the dream at this level. To receive all of those awards and with a nice crop of talented Big Ten freshman this year, it was (quite) an accomplishment. That last part (the draft), obviously, people have their opinions, but I think it's still early for that process.'
Good things always seem to come early for Harris, who made his varsity team as a freshman and one year later had his coach, Brian Satterfield, convinced he had a special player. This transition has come with such speed that school officials haven't even found a suitable place to hang Harris' coveted No. 1 jersey, the one Mr. Basketball wears in the Indiana-Kentucky All-Star Game.
For Harris' parents, they've been too busy working out logistics to worry about honors and trophy presentations.
The elder Gary Harris spends time traveling extensively throughout the northern part of Indiana for his job. He and his wife, Joy, a Purdue alum and former WNBA player, have taken turns making regular drives to East Lansing, Mich., and a few nearby schools -- Indiana, Michigan, Ohio State and Purdue -- while the other parent stays home with Harris' two younger siblings.
On Friday, everyone will hop in the family car, drive 30 minutes to downtown Indianapolis and see the third-seeded Spartans (27-8) face second-seeded Duke (29-5) in the Midwest Regional semifinals.
On Thursday, Harris will be practicing in front of a crowd that is sure to include some of his closest high school friends and mentors and then playing the biggest game of his life in front of a crowd that is expected to be close to the roughly 36,000-seat capacity. The Spartans' practice is open to the public.
'I think you'll see some Royals blue in the stands down there,' Hamilton Southeastern co-athletic director Jim Self said. 'He's had a big impact on this school. I think you see more Michigan State stuff in the hallways now than I noticed before because of Gary. So I don't know if it's that there are more Michigan State fans or more Gary Harris fans.'
Harris' third trip back to Indiana might be his warmest homecoming yet.
He's found a way to play through the shoulder and back injuries that plagued him earlier this season, and he probably won't have to contend with the angry, boisterous crowds that booed him relentlessly at Indiana and Purdue. The Spartans lost in Bloomington, but won in West Lafayette.
Harris, his dad and those at Hamilton Southeastern understood why people were upset.
'Look, you've got your faithful fans who are there every day and a kid from Indiana who decided to go elsewhere. To me, that shows a lot of respect. They're booing him because they wanted him to be part of their program,' Satterfield said. 'But if they knew Gary, they wouldn't boo him.'
This time, everyone expects more cheers.
For one, Michigan State is the only Big Ten team in town this weekend. Plus, they're facing the same Blue Devils that local fans haven't forgiven for taking down hometown favorite Butler in the 2010 national championship game -- Duke's last trip to Indy.
If the Spartans beat Duke, they would again be the underdog against top-seeded Louisville, the team Indiana fans believe stole the Hoosiers ticket to Indianapolis.
Harris can't wait. 'It's good. I get to go back to Lucas Oil, Indianapolis, real close to home, right in my backyard,' he said. 'I mean it feels good to go home, but we've just got to go down there and get a win. I'll feel better even if I get two wins.'
Harris isn't the only coming home this weekend.
Duke's roster includes Indiana natives Mason and Marshall Plumlee. They're originally from Warsaw, a small community near South Bend.
Louisville has forward Stephan Van Treese, who graduated from Lawrence North in Indy, and assistant coach Kareem Richardson, who played college ball at Evansville. He also has coached at Evansville, Indiana State and the University of Indianapolis.
Oregon, the Cardinals' opponent Friday, has former Indiana State coach Kevin McKenna on its staff and Ducks assistant coach Brian Fish grew up in Seymour, Ind., about 55 miles north of Louisville.
Then there's Michigan State, which has Harris and backcourt mate Branden Dawson, who is from Gary, Ind., near Chicago. They might have to lead the charge if injured guard Keith Appling isn't 100 percent.
Spartans coach Tom Izzo has been impressed with Harris' emergence and appreciated the passion he showed by pumping his fist and screaming to the rafters after making his fourth 3-pointer in four minutes during the win over Memphis.
'You've got to be a little demonstrative,' Izzo said. 'You have to show your emotion. The flat-line thing, some people want to talk about, that's cool. What's cool about it? Why should you have to guess if a guy is feeling good or feeling bad? I believe that passion is a motivator. It drives you, and some people can hold it in, they say. I'm not a big believer in that. So I say if it's important to you, you're going to see that it's important. Gary is learning how to do that.'
Those at Hamilton Southeastern have seen it all before.
While Harris has been Michigan State's second-leading scorer at 13.1 points, Izzo, one of college basketball's most established and successful coaches, has routinely praised Harris' toughness, his defense and his ability to make adjustments on the fly. Just like Satterfield did the previous four years.
'The main thing is that he's got a great work ethic and he's always been a team player. You know, he could have done more with us, but he always played within the system,' Satterfield said. 'What separates him from most players is what he does on the defensive end of the floor.'
NBA teams have taken note. Some analysts now see Harris as a top 10 pick in June's draft, though the family has given no indication the Big Ten's top freshman will go that route.
'I'm sure that's his goal to get there one day,' Harris' dad said. 'But really, it's not something that we've even discussed or thought about any further. We want to support this ride and see how far we can get.'
The wild 12-month continues Friday and, if all goes well, Sunday, in front of a hometown crowd.
'To think he was playing in this gymnasium 12 months ago and this year he's already playing to try and get to the Final Four,' Self said, 'it's just amazing.'


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