text:
Don't forget about the special deal I am having for all of you while I am on vacation. I have noticed that the one thing you all like best is FREE SHIPPING - so here you go!!
*When you place a minimum $50.00 on line order, I will reimburse you the shipping cost when I arrive home. Be sure to NOT check the NO CONTACT box or I will not be able to contact you.
Please use this HOSTESS CODE: 7M6VN3U2
If your order is over $150.00 then do not use the Hostess Code because you will receive the Stampin' Rewards for yourself (10% of sales) - Sounds like a good deal! 10% of Free product and free shipping from me.
I can't believe that our vacation is coming to a close. We fly home today, so probably by the time you read this we will be in the air! So sad to leave this special time behind, but we truly enjoy our life in Michigan with all my classes and Dale's work at the church, and making his amazing soaps. It will be nice to be back home again. No bed feels as good as your own, right?! This card was made using a photo I found on line, then typed the words in WORD, cut them apart and sponged all the edges. I thought this card was the closest to the rocky areas we saw in Arizona and I love the verse from Psalm 18:2. I know I am a stamper and I LOVE Stampin' Up! but when I started making my own cards I did more things like this one until I was introduced to the stamps and fell in love with them.
If you love to create hand stamped cards and want to take advantage of getting everything you love at a discount then do I have a deal for you!!
Stampin' Up! is offering an extra $35 in FREE product when you purchase the starter kit. So if you purchase the Starter Kit from now until March 31st you will get a total of $155.00 in product for only $99.00 plus tax. Stampin' Up! pays your shipping on your Starter Kit. (another 10% savings!)
We would love to have you be a part of Christi's Creative Crew.
Here are some questions you might have:
Q: What are the minimum sales requirements?
A: You only have to submit $300 in sales per quarter. Hold at least one workshop a month, and you'll not only cover your sales minimum, you'll be able to pay for some of your own hobby as well. Also, you can submit your sales in any increment you wish and still get your discount and commission.
Q: What if I only want to do this as a hobby. Do I still have to have workshops?
A: Absolutely not!! Stampin' Up! Supports the hobby demonstrator just as well as the career demonstrator. You can put in your own order or collect orders from family and friends to equal the $300 a quarter minimum.
Q: Can I be my own hostess?
A: Yes, you can be your own hostess anytime you want. You can invite your family and friends into your own home and have a workshop. You would be the Hostess, receiving the Hostess benefits, and you would also be the demonstrator receiving your instant income and commission.
Q: How much does it cost to get started as a Demonstrator?
A: The Standard Starter Kit is only $99 plus tax (shipping is FREE!) You get to choose $125.00 in whatever product you want in your Starter Kit! Plus it comes with a business supply kit. Right now from January 5-March 31, 2016 you will get $155.00 in product for only $99.00 plus tax.
Q: What if I decide that I don't like it once I've started. Will I be penalized if I quit or is there a certain time frame I have to be a demonstrator?
A: You can stop anytime you choose. You simply just stop putting in your minimum sales. Stampin' Up! May send you a reminder that your sales are due, but there won't be any pressure or repercussions except loss of demonstratorship. But I guarantee you once you get started you won't want to stop!
Q: What kind of incentives can I earn as a Stampin' Up! Demonstrator?
A: Stampin' Up! Offers so many benefits and incentive to demonstrators… here are a few:
In your first 3-4 months you have the opportunity to earn FREE stamp sets from the current catalog through a program called Stampin' Start.
Every year you are eligible to earn a FREE Stampin' Up! Trip
Stampin' Rewards: You get to pick FREE items each quarter depending on your sales.
Complimentary catalog and Occasions Catalogs throughout the year
Receive our Stampin' Success quarterly magazine which includes great tips & techniques!
Pre-order new sets before they're available to anyone else.
Q: Do people really make money at this?
A: YES!! There are many demonstrators who make $5,000, $10,000 or even $15,000 plus a month. Also, every year there are cash awards given at convention for group and individual accomplishments.
Q: Do I have to recruit other Demonstrators?
A: Of course not!! However, because this is a multi level marketing company we have the opportunity to earn a residual income. The best way to earn a substantial income is by growing your team through recruiting!
Q: How much support can I expect from my upline?
A: You can expect to receive full training from me. Including business tips, ideas, stamping techniques and ongoing support through our monthly team meetings and emails! I will be your biggest cheerleader for whatever goals you want to achieve with Stampin' Up!
Q: Where will I get my ideas for my workshops?
A: Stampin' Up! Has many resources for demonstrators. The Catalog, the Stampin' Up! Web site, the quarterly Stampin' Success magazine, training videos, Stampin' discuss, and my web site. It is OKAY to copy your projects from these sources and use them at your workshops. You do not have to do everything by yourself.
Q: Are there any Stampin' Up! Events that I can attend as a new demonstrator?
A: Every 6 months there is an on-stage Live event (April and November)
Q: How do I sign up?
A: Go to http://www.stampinup.net/esuite/home/christiwaite/ and click on JOIN THE FUN!
Q: Do you really love what you do?
A: I absolutely LOVE what I do and I know you will too. The friends I've made as a Stampin' Up! Demonstrator is an amazing bonus. I hope I have answered some of your questions. I would love to share this Fabulous Business Opportunity with you today!! Please feel free to contact me!
Q: Can I rejoin if I was a demo in the past?
A: Absolutely YES!! If it's less than 6 months you need to rejoin with the same up line, if it is past 6 months that you are inactive you can join with any demo of your choice.
Thanks for stopping by!
ChristiPin It Now!


text:
YPSILANTI, Mich. (AP) - Authorities in Washtenaw County say a man got in a dispute with a co-worker over his job performance at a metal plating factory, then shot him to death.
Ypsilanti police Sgt. Thomas Eberts tells AnnArbor.com (http://bit.ly/QLmUEo ) that the shooting happened about 4 p.m. Wednesday near the Marsh Plating Corp. factory.
Eberts says the two argued about 'an issue of job performance.' He says they decided to settle the dispute nearby, and a 34-year-old resident of Ypsilanti Township repeatedly shot 29-year-old Superior Township resident Bhagavan Allen with a .45-caliber handgun.
Police say they're searching for the suspect. They didn't immediately release his name.
--- Information from: AnnArbor.com, http://www.annarbor.com

subset: commoncrawl


text:
I figure if everyone got $100 million, our problems would be over.
That's $100 million for everyone. Paid on a prepaid debit card. Even the illegals should get one, and also people who've never paid taxes.
If everyone gets $100 million, then home prices will be fine. Our economy will roar. Our problems will be over.
Join me HP'ers in this plan. I even have a nice catchy name for it:
The In God We Trust America is the Greatest Country on Earth Homeowner Rescue Wal-Mart Everyday Low Prices Fiscal Stimulus Patriot Red White and Blue Freedom Act of 2008
No way any member of Congress seeking re-election votes against this plan!
February 08, 2008
HousingPANIC calls on Congress and Bush to give every single American $100,000,000
53 comments:
Why the heck not.
- February 08, 2008 9:18 PM
- Malcolm said...
After the Patriot Act passed, I've always said that if they pass the "Peace and Freedom for Everyone" act, I'm heading for the hills.
I think the name of your act will guarantee its passing. If anyone complains, make sure to accuse them of "not supporting the troops", that always gets 'em.
- February 08, 2008 9:23 PM
That would be sweet. $250 for a gallon of milk? Count me in!
- February 08, 2008 9:30 PM
According to a recent poll, over 75% of Americans have great confidence in The Federal Reserve. We are forked
- February 08, 2008 9:57 PM
Keith, you forgot "elimination of all taxes for the rest of eternity" as part of the plan.
- February 08, 2008 10:24 PM
Americans would actually support this
- February 08, 2008 10:27 PM
By the U.S. Gov'ts logic, I could be flat broke, and in deep debt even, but I should 'stimulate' my home budget by going out and getting another credit card and run it up to the max.
R.I.P. America!!
The Feds killed it.
- February 08, 2008 10:29 PM
1 million a piece would be fine enough for me.
- February 08, 2008 10:30 PM
Yeah baby.If had a million I might get laid.The basement is rough these days.My blow up doll is tired.On my realtor wages I cannot afford a new doll.Can you guys help a homie out?
- February 08, 2008 10:41 PM
That sounds like NESARA Keith!
(National Economic Security And Reformation Act.)
Monitors elections and prevents illegal election activities of special interest groups.
Creates new US Treasury currency, "rainbow currency," backed by gold, silver, and platinum precious metals.
Returns Constitutional Law to all our courts and legal matters.
Initiates new U.S. Treasury Bank System in alignment with Constitutional Law.
Eliminates the Federal Reserve System.
Restores financial privacy.
Retrains all judges and attorneys in Constitutional Law.
Ceases all aggressive, US government military actions worldwide.
Establishes peace throughout the world.
Initiates first phase of worldwide prosperity distribution of vast wealth which has been accumulating for many decades.
Releases enormous sums of money for humanitarian purposes.
Enables the release of new technologies such as alternative energy devices.
I'm not sure what to think about it, but they do have some good ideas. Some people call it a scam.
Although its much better than the bushco senate/house crash, constitutional crises, PNAC, GOP lies, surging bubbles, 9/11 cover-ups and massive global war agressions!
Stand up Americans!
Check it out at www.NESARA.us
- February 08, 2008 10:46 PM
- Mitesh Damania said...
The NWO maybe doing to us (using debt as a weapon) what they've done to the third world.
Anyways, another interesting John Perkins video. near the end he talks about the media:
- February 08, 2008 10:49 PM
Small town broker says:
Take your government check to the bank and cash it.
Take it all in coin.
$1,000 USD in coin is about 50 lbs in copper.
Copper @ $3.00/lb x 50 = $150.00 intrinsic value.
It will always be worth face and how long before intrinsic value exceeds face?
Bonus, If you don't deposit it they won't be able to use is as reserves for more lending.
- February 08, 2008 10:58 PM
I am so freaken pissed off at the congress. $75k cut-off is not a high limit in my part of the country! It should be $100 to $150k to cover the entire middle class.
The congress screws me again.
- February 08, 2008 10:59 PM
I get $100,000,000 and I'm shopping at WalMart?
Think again, Keith.
I'm splurgin' on COSTCO baby!
Wal Mart is for them poor people.
And no more Mack-Donalds. We're going to Appleby's and we're orderin' STEAK! Yeah, suck it. Woooooooooooooooo!
Whaddya mean they cost $1.5 million a pound, now? I want my gol-durn STEAK goldurnit.
- February 08, 2008 11:22 PM
If everyone is a millionaire, then nobody will work anymore and we'll all starve to death.
- February 08, 2008 11:30 PM
Small town broker says:
Hmmm, Nickels
A nickel weighs 5g
453.59g = Lb.
459.59 / 5 = 90.72 nickels per lb
90.72 nickels / 20 = $4.54 nickels per lb
A nickel is 25% nickel and 75% copper.
2/8/08 nickel spot = $12.30/lb and copper spot = $3.40/lb.
So intrinsic value of a pound of nickels.
$12.3 x .25 = $3.08
$3.4 x .75 = $2.55
Total = $5.63 intrinsic value?
- February 08, 2008 11:44 PM
Wonky said...
Keith, you forgot "elimination of all taxes for the rest of eternity" as part of the plan.
February 08, 2008 10:24 PM
Right, the goobermint can just print all the money it needs.
- February 08, 2008 11:48 PM
Anonymous said...
I am so freaken pissed off at the congress. $75k cut-off is not a high limit in my part of the country! It should be $100 to $150k to cover the entire middle class.
The congress screws me again.
February 08, 2008 10:59 PM
Yeah, $75K does not go very far in Southern Mexifornia, unless you want to live like an illegal, that is. I guess then you could have an Escalade with some big shiny rims.
- February 08, 2008 11:53 PM
Wow! A Million MIGHT even pimp my bicycle. Phat tires & bling wheels!
Loaf of bread,..well who need to eat when your looking guuud.
- February 09, 2008 12:10 AM
If we were prepared to perpetually balance our books, this would be the right thing to do. A one time giveaway that erases all debt, all inherited privilege, and let free markets and liberty reign!
But we are not prepared to do that.
Too bad, really.
- February 09, 2008 12:16 AM
- Princess Mononoke said...
I'm game! Count me in... ;)
- February 09, 2008 12:36 AM
- Princess Mononoke said...
Ha Ha Ha...
President Bush said today that HE inherited a recession when HE took office! What a maroon...
- February 09, 2008 12:38 AM
I thought of this at a very young age but after i thought about it I realized that if everyone had money we would have even more problems. The biggest problem would be, how do you spend money when no one works because we are all rich? You think the USA is dumb now, there would be no incentive to go to school because everone already has money. Most of the smart people would simply take the money and leave the country. And last but not least how do you control rich sheeple?
This plan is flawed even in theory. Nice try though!
- February 09, 2008 12:44 AM
I'm all for it. Can I get Greenspans picture on my debit card?
- February 09, 2008 1:03 AM
- Paul E. Math said...
This is what makes me think that inflation is more of a threat than deflation. With a Democrat in the White House and a Democratic controlled congress, there could be no end to the series of 'fiscal stimulus' packages issued.
There could the the universal health care / fiscal stimulus package. There could be the social security / fiscal stimulus package. Where will they stop?
I see a government that is entirely devoid of fiscal responsibility, utterly myopic in it's outlook and shameless in attempt to garner votes. The electorate has already proven an inability to see through this grand-scale scam.
It doesn't end until foreigners wake up and stop lending us the money to go deeper into national debt. Only then will the long rates on govt bonds rise and then we get deflation.
Asset deflation and commodity inflation now; asset deflation and commodity deflation 2 years from now. This thing is ugly and it's going to stay ugly.
- February 09, 2008 1:20 AM
Bonus, If you don't deposit it they won't be able to use is as reserves for more lending.
Do you really think they need deposits to loan out money??? The 10:1 ratio of fractional reserve banking went away long ago. Just borrow the money into existance.
- February 09, 2008 1:27 AM
When you get your checks, just remember that I have a 1983 Toyota Corolla for sale. Runs good!
Only $35,000
It'll be great when we get those checks. No one will have to work anymore. We can all retire!
- February 09, 2008 2:59 AM
- Osman said...
Thanks for the laugh Keith. Literally found myself chuckling out loud on this one. I think we're on the same page with how ridiculous the tax rebates are. Flippin' ridiculous.
- February 09, 2008 3:04 AM
- AndrewHac said...
OK... Joe6Pack & JaneZinfandel, let's get this simple, no brainer fact into that fried-burger brain one more time.
Owning a house is not for every one in the planet Earth, particularly in the land of the Americano AKA the land of the Snapper Turtle. If a person, a married couple or a family of chumps are poor, ignorant, uneducated, illiterate, buck-teeth, obese, fat, plain ugly or just looking like a piece of human crap, then that entity or organism is not entitled to own a house, or allowing to think of owning a house, or even dreaming of owning a house. Got it ? A very simple truthful fact to internalize based on Charles Darwin's famous theory: "You don't own jack if you ain't got jack to prove that you've got the jack to jack with..."
Furthermore, if that particular Americano had voted for "Little Boy + Fat Man" AKA "Dubya Shrub + Penis Shooter" in the last 8 years, then homeboy and homegirl HillBillies and Homer Simpson all alike out there should not consider a house as a place to live in. His and/or her adobe is to be in the horse ban, the chicken shack, the ass stall, or more fittingly, the Snapper Turtle lodge.
So, Hicks and CrackerNutheads out there, the 64 millions dollars question is:
"Is the Americano roasted yet, and if not, how long before the Americano will be roasted slowly, nicely and juicely like a snapper turtle skewered on a Chinese bamboo stick from mouth to ass sizzling, fat popping on a bed of white hot charcoal ?"
Are we there yet ? Is Joe6Pack still alive, breathing and kicking ???
- February 09, 2008 4:12 AM
If everyone is a millionaire, then nobody will work anymore and we'll all starve to death.
Not true.
If Everyone is a millionaire, the median house will cost a billion.
- February 09, 2008 4:53 AM
Why not?
I've got a couple billion in weimer marks in a drawer in the kitchen.
Hey I'm a billionaire!
- February 09, 2008 5:06 AM
Read this on the kitco.com gold forum. Chew on it:
Like usual, DC is right on! The definition of Recession is negative GDP growth for two consecutive quarters. Inflation must be subtracted from growth numbers to calculate GDP or all that is being measured is the relative cost of things. Therefore, if inflation was being honestly reported (which it is not), the USA would have been in 'Recession' for more than a year.
Gold is up $250 year to date.
The 'Official' remedy for Recession to to lower interest rates, ie. print more fiat.
Bullish or Bearish for Gold?
I'm not trying pushing gold. Just think the GDP - Inflation = recession sits heavy.
- February 09, 2008 5:08 AM
- whitetower said...
Make it a cool billion and I'm with you.
- February 09, 2008 5:24 AM
As this is the end of an Empire I want to get everything "due to me" not only do I want my $100,000,000 I also want the 200 and some holidays they enjoyed at the end of the Roman empire. I feel I am due this because I live in DC. DC=Rome. I want my circus maximus, I want my bath houses, I want my vomitoriums, I want my coliseum (with games) I want it all one last big feast for Bacchus.
- February 09, 2008 5:32 AM
Holy _ _ _ _! The S&P 500 is below 1400 which is where it was when Helicopter went into full blown panic and lowered the FFR by 3/4 point!
Oh man! Helicopter it's ok! I bet he is having a teleconference call this weekend! It's ok Helicopter we are all still alive! The stock market is still breathing!
We worry about you Helicopter! You are looking a bit pale! Possibly you should take a vacation until all this depression talk blows over. If you can't handle the pressure maybe you should step down!
- February 09, 2008 6:14 AM
- Ed said...
Come on Keith stop being so negative. My local realtor says it's people like you that are causing the housing crash with the doom and gloom. Cheer up dude and all will be well.
- February 09, 2008 1:14 PM
- Ed said...
Mock this bill all you want. But this mentality is exaclty what Hillary and Obama are promising on the campaign trail.
They won't send you a check in the mail but they will give you "FREE" health care. They won't send you a check in the mail but they will give you a "FREE" college education. And if Hillary has her way she will send you a $5K check for having a kid. Mazel Tov!!
And on and on. Listen to any speech made by either of them. It is nothing but 'vote for me and I will give you free shit'. The fight between Hillary and Obama has come down to who will promise to give the most free shit to the most people.
And yet every time Keith has a poll Obama and Hillary come in #1 and #2. Make up your minds people. Do you want socialism or not? You can't bitch about it one day and then vote for it the next. Well you can, but that would be incredibly stupid.
- February 09, 2008 1:21 PM
Anonymous said...
I am so freaken pissed off at the congress. $75k cut-off is not a high limit in my part of the country! It should be $100 to $150k to cover the entire middle class.
The congress screws me again.
February 08, 2008 10:59 PM
Yeah, $75K does not go very far in Southern Mexifornia, unless you want to live like an illegal, that is. I guess then you could have an Escalade with some big shiny rims.
February 08, 2008 11:53 PM
Then move away from Mexifornia and stop whining like a little bitch.
- February 09, 2008 1:26 PM
- Mammoth said...
Anon 5:08 AM said...
"Gold is up $250 year to date."
Oh, really? So, Gold was below $700/oz on January 1st this year?
No, it was not. Please check out the facts next time, before you parrot someone else's BS.
- February 09, 2008 2:14 PM
- Unknown said...
My family will be happy with the $1200, but I'd like to make one request. Could it please be paid in $20 gold coins at face value?
- February 09, 2008 2:56 PM
Remember, you must pay the "rebate" check back next year, it will be deducted from any refund due in the 2008 filing year. If you don't get a refund next year, that is, you owe the gov instead of them owing you, you'll get to keep the check.
- February 09, 2008 3:13 PM
"President Bush said today that HE inherited a recession when HE took office! What a maroon..."
leave it like you found it, as they say!
- February 09, 2008 3:54 PM
I've been paying attention to the Porkbuster effort, and found this small victory:
"...Here are ...members of the House who have either never sought an earmark since entering Congress or have taken the pledge not to do so in the future.
REPRESENTATIVES:Jeff Flake, R-AZ
John Campbell, R- CA
Jeb Hensarling, R-TX
John Shadegg, R-AZ
John Boehner, (OH-08)
John Kline, R-MN
Tom Price, R-GA
Lynn Westmoreland, R-GA
Virginia Foxx, R-NC
Trent Franks, R-AZ
Michele Bachmman, R-MN
Marsha Blackburn, R-TN
Eric Cantor, R-VA
Patrick McHenry, R-NC
Marilyn Musgrave, R-CO
Peter Roskam, R-IL
Paul Ryan, R-WI
Walter Jones, R-NC
Coburn of Oklahoma,
DeMint of South Carolina,
McCain of Arizona
Cornyn of Texas
Claire McCaskill, D-MO
Richard Burr, R-NC"
- February 09, 2008 4:49 PM
I can see the home builder and car dealer promotions now:
And the game continues.
- February 09, 2008 5:08 PM
Make up your minds people. Do you want socialism or not? You can't bitch about it one day and then vote for it the next. Well you can, but that would be incredibly stupid.
They don't want socialism, they just want everything free as long as it's taken from somebody else and not them.
I remember an old saying that there's no such thing as a free lunch. If you tax the corporations, they will just pass the cost on to consumers or leave. If you tax the rich, they will just move to another country. Just ask Clownifornia how that works. Businesses and wealthy people are fleeing the state, destroying to economic base. Businesses that don't leave the state are choosing to expand in other states.
Do I support the Bush criminals? No, but I'm also mature enough to know that nothing comes free.
- February 09, 2008 5:30 PM
Govt's job is to redistribute wealth. Fuck the over-paid CEo
- February 09, 2008 8:18 PM
There is no printing presses guys.
As we are currently finding out. If there were printing presses wouldn't Citi, JPM, BofA, etc, etc. Be loaded with cash. In the mean time, they have to go to Dubai, to get a loan at an 11% rate. What a deal.
There is no printing presses here guys.
- February 09, 2008 9:56 PM
Hoo boy, I sure am glad I decided to become a no-good slacker last year. Went from $130k to about $50k, so there's a big, fat $600 in the mail for me as we speak! W00T!
If they gave me a million, I would emigrate instantly and renounce my citizenship. By the time Joe Handout figures out that the Deficit Fairy isn't going to wave her magic wand and erase the national debt, it will be too late.
- February 10, 2008 1:37 AM
I've got a better idea: abolish money and make all goods and services free for everybody. Gasoline will be free - just take what you need and so will food and guns and luxury goods. We just have to work and do our jobs to keep it all working.
C'mon sheeple you can do it. C'mon.
Thank you King Bush II.
-Big Cheese
- February 10, 2008 5:42 AM
Yes, $100 mega bucks for everyone!
Oh, BTW, the top marginal tax rate has also been increased to 99.999%.
- February 10, 2008 11:41 AM
Lets do it
- February 10, 2008 6:11 PM
give everyone 100M.... I am sure it has been talked about as a way to eliminate poverty.
along the lines of hillary healthcare: force everyone to buy med insurance, problem solved!
I have a solution for hunger: pass a law that requires everyone to buy enough food so they won't go hungry!
- February 11, 2008 7:43 PM
Ha Ha Ha...
President Bush said today that HE inherited a recession when HE took office! What a maroon...
jokes on you. he did inherit a recession. How old are you? to young to realize it was a recession? Parents won't let you onto wikipedia? try searching wiki for "early 2000s recession"
- February 11, 2008 7:47 PM


text:
What's Your Favorite Database and Why?
When: Wednesday, May 8, 2-3:30
Where: IC Classroom
We have 1,249 databases at last count. How do we recommend a database to a scholar? Scholar status and discipline are key. What about ease of use and special features (alerts, personalization, citation info)? How do you find specific content such as think tank papers or case studies? How about ebooks?
Let's all learn from each other:
- Appreciate a database you've never used
- Brainstorm the features you expect and "must have"
- Strategize how we can share knowledge about databases among ourselves
Do you have a favorite database you would like to share? If so, let us know by Friday, May 3. Kris Kasianovitz will be presenting CIAO and Phyllis Kayten will be presenting Policy File.
We will also break into smaller groups and explore other databases so bring a mobile device or grab a laptop from the cart.
Come to the IC Classroom prepared for a lively discussion on the features we most like and dislike and how to find particular content in the databases we use.
Congressional Publications - historic Congressional documents of all types and covering an amazing array of subject areas. Check out hearings, CRS reports, House/Senate documents and reports, bills and more.
IGO and NGO search - we've built google custom search engines subsetted to the top Intergovernmental Organizations (UN, World Bank, OECD etc) and Non-Governmental Orgs (Greenpeace, food policy research institute and 1600 others).
Reference Universe - database of back-of-the-book indexes to subject encyclopedias and other reference works in a wide variety of subject areas. The best part is, Reference Universe can be used to access Stanford Library's extensive reference collection including our growing number of digital reference resources. The first stop for any researcher!
EspaceNet - Espacenet's worldwide database enables you to search for information about published patent applications from over 90 different countries and regions. Espacenet also offers free access to more than 70 million patent documents worldwide – most of them patent applications rather than granted patents – from 1836 today. Includes the full-text for U.S. patents. It is possible to print and download documents.
EOLSS - (Encyclopedia of Life Systems Support) An integrated compendium of sixteen encyclopedias. It attempts to forge pathways between disciplines in order to show their interdependence and helps foster the transdisciplinary aspects of the relationship between nature and human society. It deals in detail with interdisciplinary subjects, but it is also disciplinary as each major core subject is covered in great depth, by world experts.


text:
7 Strollers Moms Love
Height-adjustable handles, extendable hoods, cup holders, car seat attachments, zip-off diaper pouches…strollers today nearly offer more options than new cars! Given the extensive menu of choices, it's easy to feel overwhelmed when stroller shopping. To help you find the best strollers for your family — whether that means a lightweight, double, or jogging model — we're spotlighting 7 great strollers that earn rave reviews from Circle of Moms members.
1. Baby Jogger City Select
Great for moms on the go, the Baby Jogger City Select features a hand-operated parking brake, front wheels that swivel or lock, multi-position seat recline and sun canopy, lots of storage space, and a 45 lb seat capacity. As Amber S. shares, it makes a great jogging stroller: "I LOVE my City Select. I use it to run, walk, or stroll and it can be a double or single...in my opinion it is by far the best stroller out there!"
2. MacLaren Quest Sport
Looking for the best lightweight strollers? Consider the 12 lb MacLaren Quest Sport, which moms also like for being easy to maneuver and simple to fold. Laura E. shares: "Got the MacLaren Quest, which I LOVE because it reclines and folds ridiculously easy." Mel P. offers similar input: "I like my MacLaren — at 12 pounds, it is so light, and easy to maneuver." The MacLaren Techno also received recommendations from Circle of Moms members.
3. Graco Duo Glider
The tandem-style Graco Duo Glider also earns great reviews in Circle of Moms conversations. As Sunrise B. relayed: "I had a Graco Duo Glider and it was...easy to fold/unfold and go, lightweight and easy to push." The model also features "stadium-style seating" (the seat for the child in back is higher), reclining seats, canopies and footrests, an extra-large storage basket and a one-hand fold.
4. Valco Baby Trimode EX
As far as Circle of Moms member Rebecca is concerned, this all-terrain model is one of the best double strollers on the market: "I have a Valco Baby Twin Trimode with the additional toddler seat…It fits through a standard doorway and has 3 wheel modes depending on the surface you are pushing it on. Dual zip-off pouches on the back for diapers and a height adjustable handle for comfort when mom and dad switch stroller duty. Also has a zip-on UV bug and sun screen. Extendable individual hoods. Oh the list goes on. I love it and it was worth every penny!"
5. BOB Revolution SE
With a sturdy frame, adjustable suspension, large sun hood, fixed or swivel front wheel option, and a tracking device, many moms find this is one of the best jogging strollers to consider. Korrisa shares of her BOB stroller: "Oh. My. Goodness…It's so great my daughter who hates to be in strollers refuses to get out of it! Well worth the money. No regrets." Of course, it's not only for running! Grace B. shares: "I am NOT a runner but I love this for taking to the grocery store, on a walk, at the beach (it goes right through the sand), and even to use when my son is napping! Awesome awesome stroller!!!! Well worth the money."
6. Combi Flare
Looking for the best travel umbrella strollers? Several Circle of Moms members recommend the 11.7-pound Combi Flare, which folds compactly (to 10"x16"x40") and comes with a shoulder-carrying strap, bumper bar with cup holder, and an adjustable recline. X shares: "I have a Combi Flare and I just LOVE it! Very light and folds so small, handles are tall enough for hubby too."
7. Bumbleride Indie Twin
Corrie M. calls her Bumbleride stroller "THE MOST AMAZING stroller you will ever find." Why? "It goes in every terrain condition with ease. We've had it on trails, gravel, even in sand! And it was so easy to push and maneuver. It also fits through a SINGLE doorway so you don't need help getting in and out of stores, etc., it has so many accessory options you can't even begin to imagine (sleeping bags!!!). We've traveled domestic and international by car and by plane with the stroller, again no issues, the axles detach for compressed folding and easy storage in a cargo carrier if necessary….I can easily set-up, fold, and store the stroller by myself. It's great for jogging and the kids at 2 still love to ride in it."


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All-American Barbecue Sandwiches
Total TimePrep/Total Time: 25 min.
Makes18 servings
- 4-1/2 pounds ground beef
- 1-1/2 cups chopped onions
- 2-1/4 cups ketchup
- 3 tablespoons prepared mustard
- 3 tablespoons Worcestershire sauce
- 2 tablespoons vinegar
- 2 tablespoons sugar
- 1 tablespoon salt
- 1 tablespoon pepper
- 18 hamburger buns, split
- In a Dutch oven, cook beef and onions until meat is no longer pink and onion is tender; drain. Stir in the ketchup, mustard, Worcestershire sauce, vinegar, sugar, salt and pepper. Heat through. Serve on buns.
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Jul 12, 2020
Great recipe. But sorry, you didn't invent this recipe. It's been around for many, many years. Poor man's food. From coal region of PA.
Apr 9, 2019
No comment left
Sep 22, 2016
A hit at the party. Ran out of ketchup so I used 1 c ketchup, 1 c bbq sauce and 1 can tomato sauce. Yum! I did take another reviewer's suggestion and did 3/4 tbsp pepper as well.
Sep 12, 2015
Delicious!!! Best bbq's ever!
Jan 7, 2014
This is one of my family favorites. I have made it several different ways, but found the tastiest is with half bbq sauce in place of 1/2 of the ketchup. This is a easy and versatile recipe. Enjoy!
Jun 8, 2013
No comment left
Apr 17, 2013
No comment left
Jul 15, 2012
My kids love this! I don't need this much at one time so I freeze part of it for a meal when our lives are crazy & hectic.
Jul 15, 2012
Ever since I saw this in one of my first Taste Of Home magazines, this is the only beef barbecue that I make. Although we love it, I do think there's too much pepper in this recipe. I suggest cutting it down to 1/2 or 1/3 TBP pepper.
May 15, 2010
I made these when the recipe was first published..and they have been the only Sloppy Joes my people will eat. I have to scale down the recipe most of the time, but that isn't difficult. this freezes very well...for times when company shows up unexpectedly, or I'm too tired to cook in the evening. Good Sammies, these!


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Experience our difference. Experience the IQVIA CORE?
Almost everything we do in Human Data Science is powered by the IQVIA CORE. This holistic approach allows us to generate unique perspectives that we use to create solutions for our customers. By infusing the CORE into everything we do, we can help our customers rethink approaches to clinical development and commercialization, reframe old challenges into new opportunities, and reimagine what's possible.
Learn more about how the components of the IQVIA CORE come together to channel the insights, commercial and scientific depth, and executional expertise that drive maximum value for our customers:


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As we sort through our data we have found that the number one searched manufacturer in the state of Georgia is Ford, followed by Chevrolet in second with Toyota as the third most searched automotive manufacturer in Georgia. Our research and analysis did not stop at the top three, scroll down and find a complete list of the top 10 searched manufacturers in Georgia below.
After combing through millions of vehicle listings we found Mercedes-Benz to be the fourth searched Make in the state of Georgia.
Out of 18,721 Mercedes-Benzs listed nationwide we found 335 Mercedes-Benzs available in the state of Georgia.


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Women are the majority (56 percent) of students enrolled in both undergraduate and graduate institutions
The Gender,
Diversities, and Technology Institute at EDC leverages
the power of diversity to improve education and work systems
through innovative technology design and use.
In our work, we:
The Institute is currently developing a book on gender equity and education entitled Living Life: Stories of Women, Men and Changing Roles in the 20th Century. Click here to read more and see how you can get involved.
The Effective Access project recently released a final report
culminating 3 years of research on science, technology, engineering, and mathematics (STEM)
educators' use of digital resources. The project, funded as a part of the National Science
Foundations National Science Digital Library (NSDL) program, focused on high school STEM
educators as an important and broad subset, as high school STEM remains a priority of
education reform in the United States. Available on-line.
Students and teachers have a lot to say about how gender equity works for them. Hear their
voices, see their experiences, and learn about how gender healthy schools can make a
difference-engaging students, reducing tensions, increasing academic interest, and building
youth leadership. Click
here to learn more about Gender Healthy/ Respectful


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22 April 2013 | News | By BioSpectrum Bureau
University of Florida and University of Southern California to use Toshiba America Medical Systems' Vantage Titan 3T MR system for Magnetic Resonance Imaging (MRI) and imaging research
Singapore: Toshiba has partnered with Shands at the University of Florida (UF) and the Keck Medical Center of the University of Southern California (USC), US, for research in Magnetic Resonance Imaging (MRI), as well as body and cardiac imaging.
UF and USC are among the several leading research institutions that are making breakthroughs in advanced MRI with Toshiba America Medical Systems' Vantage Titan 3T MR system.
Dr Anthony Mancuso, professor and chairman, Department of Radiology, College of Medicine, UF, said that, "We're utilizing the Titan 3T MR to enhance visualization of Cerebral Spinal Fluid (CSF) flow non-invasively and in the research of traumatic brain injuries from combat and athletics. The Titan 3T fulfills all the promises of a high-end 3T system, with high image quality, gradient homogeneity and patient-focused features."
"Partnering with prestigious universities such as USC and Shands at the University of Florida illustrates our commitment to developing advanced technology that can expand the potential clinical applications of MR imaging," said Mr Suresh Narayan, senior manager, market development, MR Business Unit, Toshiba.


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Social Media Updates from Skiregion Brauneck - Wegscheid
Missed the recent news, photos, videos or hilarious meme from Skiregion Brauneck - Wegscheid? Stay up to date with everything happening at Skiregion Brauneck - Wegscheid through the mountain's Facebook, Twitter and YouTube feeds compiled here into one convenient view. Use the tabs to see the latest Tweets, Facebook posts and YouTube videos from Skiregion Brauneck - Wegscheid.
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Skiing in Germany: So close, yet so overlookedGermany offers the closest skiing to the UK, with some of the prettiest resorts and cheapest lift passes in Europe.
Whiteout In Germany: 42cm Of Snow By The WeekendGermany has its most widespread snowfall of the season: 30-42cm forecast in 50 resorts by the weekend.
Firsthand Reports
Ski and snowboard enthusiasts from around the world:
We have been proud to provide you with free access to snow reports, resort guides and more, and we are beyond grateful for your readership and contributions to our community over the years.
Unfortunately given the changing media landscape, Mountain News Corporation has experienced financial declines in recent years. With additional economic challenges from the COVID-19 pandemic now facing our business, it is not financially viable to continue operating.
Mountain News Corporation and our OnTheSnow and Skiinfo websites will be shutting down. We will explore the possibility of selling, partnering, or contributing assets to another media outlet if there is an opportunity to allow for a consistent or enhanced online experience. For inquiries about Mountain News Corporation, please email email@example.com.
We want to thank our loyal employees for their tireless work over the years to bring great information to all of you. We take comfort knowing that our collective passion for the sport of skiing and snowboarding will certainly live on.
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– Mountain News Corporation


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SPRINGFIELD, Ill. — Anyone who doubts the division in Illinois over gun control need look no further than the state House on Wednesday, where a pro-gun Republican — goaded by a Democrat — exploded during debate over whether the state should adopt a concealed carry law similar to New York's.
It put the presiding officer in the virtually unprecedented position of yelling for order and threatening to call doormen, presumably to remove overheated Republican Rep. Mike Bost, who calmed down once, only to blow up a again after a snarky response from his tormenter.
"So here's my point, members: We don't want someone like that carrying a concealed weapon," Democratic Rep. Scott Drury, who had the floor, deadpanned after the chamber came to order.
Drury's quip brought Bost to his feet again, which drew an even sterner warning from Assistant Majority Leader Al Riley, an Olympia Fields Democrat who held the gavel. Riley demanded deference to the chair and added, "The next thing I will say is I will call the doorkeepers."
It was all over an amendment that failed miserably, 31-76.
Since a federal appeals court ruled in December that Illinois must abandon its status as the nation's last state to prohibit the concealed carry of firearms, gun-rights advocates have been frustrated by Chicago Democrats who have their own ideas about what shape that law should take.
Bost, who is from the southern Illinois community of Murphysboro, stood to oppose an amendment to a bill by Chicago Democratic Rep. Kelly Cassidy. It would legalize concealed carry but authorize each county sheriff to deny individual permits, with the state police having the final say. Bost questioned the constitutionality of such a "may carry" provision.
Freshman Rep. Scott Drury challenged the notion, noting that the U.S. Supreme Court refused to hear an appeal over the constitutionality of New York's law — "the only opinion we have on the books from constitutional scholars."
"The last time I looked around, there's not one single constitutional scholar sitting in this chamber," said Drury, a Democrat from Highwood, in north suburban Chicago. "So why don't we stop with all the nonsense?"
Bost, without aid of a microphone, started yelling, pointing at Drury and pounding his desk. That led to Riley repeatedly calling for order.
After things settled down a second time, Riley directed Drury to show respect in his comments too.
Bost later apologized to Riley. A few minutes later, Drury apologized, claiming his comments were not meant to be taken personally.
The 7th Circuit U.S. Court of Appeals declared Illinois' ban on concealed carry unconstitutional and gave the state until early June to enact a law.
Bost said he was initially angered that Drury claimed complaints were only coming from the GOP side of the House, when opposition was also voiced by Democratic Rep. Brandon Phelps, who is from the southern Illinois community of Harrisburg. Phelps is sponsoring "shall carry" legislation that would require police to give permits to anyone who passes a background check.
The gun issue in Illinois divides more along regional lines — anti-violence Chicagoans versus sports-shooters, hunters and conservatives outside the city — than it does along strictly political lines.


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Discussion Starter • #1 •
I am looking to replace the shocks on my 99 K1500. I am buying a 2" lift/level kit soon, and want some longer shocks to go with it. I am a fan of Rancho shocks, but I am open to suggestions for better. Whats the difference between gas and hydraulic ones? Is it worth the price difference? What do I look for in a shock? Any input is helpful, thanks in advance!


text:
The Lieutenant rolltop messenger bag from Chrome is versatile, stylish and is waterproof inside and out. The fact that it is a rolltop means it can handle a variety of different sized cargo that is easy to get to. It has dual waterproof compartments that keep the wet and dry cargo separate. It will keep your items dry if it is rainy and we love the fact that it doubles as a portable cooler for our Pliny. The iconic Chrome buckle also serves as a bottle opener!
We tested the Chrome Lieutenant for months and it has proven to be very durable on our commute rides, whether that commute was by pedal power or by motor bike. The two external pockets are easy to get to and provide easy and quick access to tools, wallets, phones and other small items. And on those odd days when we got stuck at the office late, there is a handy loop between those two pockets (just above the red Chrome logo) for our blinky.
Although we were initially concerned with how secure the velcro closure would be, we never once had it come loose on us. The Lieutenant will fit up to a 17″ Macbook Pro and we regularly carried our laptop in it (with a sleeve, not included). Other cargo options could include your favorite beverage of choice and ice to keep it cool (this method also serves as a way to keep the rider cool on hot days.)
The construction of the bag is weatherproof 1000 denier Cordura outer shell and waterproof 1800 denier military grade truck tarpaulin liner with bar welded seams on the inside. The shoulder strap is nice and large and contains EVA foam for padding. There is a cross-chest load stabilizer for increased stability however we would have also preferred the option to run the strap around the waist (not just under the arm) for those mad dashes to catch the bike car on Caltrain. The only other thing we would add would be a carry handle for those times when you remove the bag from your back and just need to move it from place to place without actually wearing it.
The bag is pretty big, which is always hard to tell from product photos, so we've included some shots of the Lieutenant while being carried. The physical dimensions are 21.5" wide, 15" high, and 5" deep with a carrying capacity of 26 liters. At 3.4 lbs, the bag is a bit hefty but that's the price you pay for the cool hardware.
Best of all, the Chrome Lieutenant is part of the Heritage Line from Chrome, which are all made by hand in Chico, CA. To back up that hand made quality, Chrome offers the best warranty in the business. The Chrome Lieutenant is guaranteed for life!


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It looks like the Wii U may be sold out, my friends, which means it's time to put on black and go into mourning. Gnash your teeth. Wail. Shrug if you couldn't care less. Or, of course, reach deep into your pockets and pull out wads of cash to pay that sordid segment of the secondary market more than happy to guarantee you a system on launch day for roughly 1000% markup.
I just checked GameStop — both the $300 Basic and $350 Deluxe models are sold out, and as I understand it, have been since late September, just after preorders began. Target lists both models on its website but not a button to preorder them. Kmart's listing is basically the same as Target's. And Toys 'R' Us says the Wii U will be available at launch, but to "check back soon to pre-order."
Walmart's online listing for the 32 GB model (I couldn't find the 8 GB version) won't let you order online, showing "In stores only" and allowing you to check store availability. I ran a quick search around Michigan, near Ann Arbor (where I live) including Detroit, and not a single store lists the system as "carried." It's the same story in Los Angeles, New York and Miami. At this point, I'm assuming your only chance of buying a Wii U from Walmart is going to involve waiting in line on launch day, Nov. 18.
Best Buy lists the Wii U as "sold out online." Fry's isn't carrying the Wii U (yet, anyway — it just lists a handful of games). Neither Micro Center nor H.H. Gregg are carrying anything for the Wii U at this point, so they may or may not be launch day options. Sears is carrying the Wii U, but doesn't appear to be pre-selling it (the company's website says it'll be available in stores at launch).
It's the same story at Amazon — the system's sold out, except here you'll start to see the third-party price-gougers doing their thing. Right now, you can buy a "new" Wii U through Amazon starting at $490 (and climbing — one seller's offering the system for an unhinged $1 million), a "collectible" version starting at $698 (except there is no collectible version — doesn't Amazon have a way to weed out false advertising?) and someone with the nerve to claim they have a used model to sell ("Used only a couple of times. Comes with original box and paperwork. Also comes with Mario Bros. U") for just under $800.
Hop over to eBay and it's as you'd expect, with bidding wars in the $300 to $500 range, to ambitious listings asking $3,000 "or best offer."
I scouted for Wii U sales trackers and didn't find much. There's NowInStock.net, which lists the Wii U as "out of stock" everywhere, save eBay. Another tracker, zooLert, currently reports the same. I'm seeing a few other amateur trackers out there, but they haven't been updated in months.
In short, if you're just tuning in, thinking it'd be fun to have a two-screen game system (and a new Mario game) on tap for the big family get-together next week (Thanksgiving — I know, it snuck up on me, too), it's sadly too late to preorder. Which means your best bet come Saturday midnight or whenever your local retailer opens to sell the thing, is going to be standing in line.
Or is it? Is the Wii U really that popular already, or is the problem on Nintendo's end with shipment allocation? According to a report on NASDAQ.com, Nintendo could well outperform the Wii in unit sales by the close of the year — 3.5 million units sold, say analysts, compared to the original Wii's 3.1 million back in 2006.
But in the same piece, employees for GameStop indicate that some stores may not hold midnight launches because they haven't been allocated enough units (an unconfirmed report citing a GameStop store manager suggests the reason may be security concerns, though that didn't stop the company from midnight-launching the Xbox 360, PS3 and Wii).
As usual, it's unclear what the problem is, but Nintendo seems upbeat it can keep the systems rolling.
According to Nintendo of America's VP of marketing, Scott Moffitt (speaking to Venturebeat), Nintendo intends for product "to be available on day one in stores throughout the country." It's not clear who's who in that lineup, but it's safe to assume anyone who didn't opt to sell through their allocation in preorders should have a few, and Moffitt specifically names GameStop as having "not sold all of their day one allocation."
Moreover, says Moffit, Nintendo is doubling down on claims that it'll have "more Wii U units on store shelves in week one than we did for Wii in 2006" and that it'll "also have replenishment much more frequently during the holiday than we did for Wii."
And according to Tiffany Cho, a manager with Nintendo of America who confirmed the following to me Tuesday night, Nintendo is "doing everything [it] can to get as many systems into the hands of shoppers as possible during the holiday season.
"We are providing retailers with regular shipments of Wii U through the holidays and into 2013," added Cho. "As Mr. Iwata announced, we expect to ship 5.5 million Wii U systems worldwide by the end of March."


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30 different people that influenced my life were painted one on top of another on my torso. I either painted a picture of the person or an object that represents the person.
Many people are asking about Hitler and how he could be an influence. He has had an impact on the entire world and changed how society deals with hate. Obviously he is not a influence in a positive way except for the positive changes that have occured to society since his existence.
People are also wondering how long it took. I spent 20 hours painting and I had the piece on me for about 30 hours. I slept with it on and it was aweful!
Source: philinthecircle.com/influence


text: K.G. McAbee has had several books and nearly a hundred short stories published, and some of them are honestly quite readable. She writes steampunk, fantasy, science fiction, horror, pulp, westerns and, most recently, comics. She's a member of Horror Writers Association and International Thriller Writers and is an Artist in Residence with the South Carolina Arts Commission. Her steampunk/zombie novella recently received an honorable mention in the 3rd quarter Writers of the Future contest.


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The 100 Moments of TSU Athletics presented by Taco Bell® series continues by remembering the only teams to win an OVC Championship in Tennessee State football history.
In 1998 under the guidance of head coach L.C. Cole, the Tigers won nine games including six in the OVC to take the conference championship. TSU had an even better season the following year, going undefeated and winning another conference title.
The key to the team's success those two years was its explosive offense. The Tigers scored 430 points in 1998 and 426 in 1999 which rank second and third on the all-time scoring list.
The focal point of the offense was the passing game led by quarterback Leon Murray. Murray became the only Tiger to throw for more than 400 yards in a single game in 1998 en route to 3,002 yards. Murray also tossed 22 touchdown passes in 1998 and 18 in 1999. Most of those scores were received by Tyrone Butterfield in 1998 and the two-headed attack of Corey Sullivan and Avion Black in 1999.
In the game against Southeast Missouri in 1998, Butterfield caught a school-record 13 passes, helping him tie for the all-time record of 72 passes caught in a single season. In the game versus Murray State, Butterfield had a TSU-record 249 receiving yards in the Tigers' thrilling 46-44 victory.
Sullivan and Black combined to catch 116 passes for 1,816 yards in 1999. Six of Sullivan's 66 catches went for touchdowns, while Black played the role of a down-field threat by averaging 19 yard per reception for 894 yards.
Black was also arguably TSU's greatest return man. In 1999 alone, he had four kickoff returns for touchdowns including a school-record two returns of 100 yards. He also holds the mark for the highest kickoff return average with 37 yards per return. That means that the Tigers averaged great field position whenever Black returned a kick.
Black's big-play ability allowed him to get drafted by the Buffalo Bills in the fourth round of the 2000 NFL Draft.
Defensively, the 1998 and 1999 Tigers were anchored by defensive end Lamar Carter. Carter left TSU with 40.5 sacks which is 1.5 more than both Richard Dent and Claude Humphrey, and two more than Joe "Turkey" Jones and Ed "Too Tall" Jones. The team also featured a pair of dominant linebackers in Ed Sanders and Brent Sterling who combined for 197 tackles in 1999.
Overall, TSU had five All-Americans on the championship teams and compiled a 13-1 record in the OVC.
The 100 Moments of TSU Athletics presented by Taco Bell® highlights some of the greatest moments in honor of Tennessee State's centennial celebration. A new moment will be released each weekday for a total of 100. These moments were chosen by the TSU 100 Moments committee, which consists of alums from various departments. TSU has so many great moments, not all can be represented in these 100.
Sports Information Assistant Alex Mitchell contributed to this article.
Follow TSU Athletics on Facebook.com/TSUTigers and Twitter @TSU_Tigers.


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An Interview with Alan Cox
Welcome to the unexpurgated version of Linux Journal's Linux Kernel Who's Who. If you haven't yet seen our June 2000 issue, which features 40 profiles of some of the kernel's pioneers (hackers like Lars Wirzenius, Pauline Middlelink and, of course, Linus Torvalds), make sure you get a copy from your nearest newsstand - or your nearest Linux Journal web site. If you have already read the profiles, then our unexpurgated versions of the original interviews, which were e-mailed to each major contributor to the Linux kernel, may reveal a few surprises, and a lot more detail.
We'll be posting the original interviews here on the Linux Journal web site over the next several weeks. So sit back, and enjoy a few words from some of the folks who helped make Linux possible!
--David Penn
Linux Journal: How did you first learn about Linux? What were you doing in your own life at the time?
Alan Cox: I was hacking bits of ideas for my own OS and working on a MUD called AberMUD. I had pondered getting a decent PC, since the Amiga was getting a bit long in the tooth. 386BSD came out, and it looked like there was finally an OS worth running on x86 hardware. Linux came out around the same time, but didn't need an FPU, so I started running Linux.
LJ: What attracted you to it, compared to FreeBSD, proprietary Unix systems, or lucrative areas such as Windows? What made you want to help with development?
Alan: Linux was a lot easier to set up in the early days; MCC Linux and then SLS made it really easy to install by the standards of the time. I looked at the BSD systems, but I liked the way the GPL meant I was writing code that nobody could run off with. I didn't really chose not to hack 386BSD; I was just having too much fun with Linux to bother.
LJ: What part of Linux were you personally interested in and working on? How are you still involved with Linux development?
Alan: Initially, I was working on the networking code after Ross Biro stopped maintaining it, and Fred van Kempen basically dropped the mainstream code to rewrite it. I ended up maintaining the code and getting it going. Nowadays, I do the stable kernel releases and a fair bit of patch merging and debugging of drivers.
LJ: What was most important to you about Linux? What's the very best thing about Linux?
Alan: I think the most important thing about Linux is that it gives people the ability to do what they want. The "Penguin Powered" logos people love should really be "Penguin Empowered". That, I think, is the best thing about Linux, too. We've given the computer back to the user.
LJ: How important was the GNU project, and how did the GNU Hurd factor in to your thinking? Should Linux be known as GNU/Linux?
Alan: I knew about GNU several years before. In fact, in many ways, Linux exists because GNU chose to pursue the Hurd rather than using UZI as their Unix OS core, as they could have done. GNU/Linux is perhaps overstating it, but ignoring the FSF contribution is even worse. Richard has perhaps made a few enemies by insisting on GNU/Linux - but it does remind people.
It's really x11/BSD/GNU/....../Linux.
LJ: What was it like to be working with others over the Internet at a time when several computer luminaries thought that organizing successful software development over the Internet was difficult, if not impossible? Did you realize how revolutionary this approach was?
Alan: I don't think it was revolutionary. People had been doing it for a long time before that, a very long time. The modern Internet and large-scale access just made that project a bit easier - the lack of people and slow networks killed earlier equivalent projects like UZI and OMU, stopping them from spreading.
One thing Linux taught me: far too many people write about software design, but have never run a real-world computing business. The folks who seem to get software design right are mostly engineers. They want it to work, they want to solve the problem and they aren't totally obsessed by reusable components, object orientation, Java ... whatever the meme of the month is.
LJ: What are you doing with your life now? What's a typical day like? How do you find time for work and Linux, and how do you balance free software with the need to make a living (or the desire to become rich)? What do you do for fun?
Alan: I work for Red Hat. I work from home, hacking free software - it's great. It's been a bit busy, but I have a lot of fun when I'm visiting shows and abroad, both meeting the people and also getting to see other places. It isn't just the shows; I've visited the depths of Iceland with a bunch of mad 4x4 drivers, spent a week in a very snowy Vienna, and been to the Glengarry Highland games in Canada.
LJ: Who do you think other than Linus has had the most influence over the Linux community, and why?
Alan: Umm, that might be me, although I try not to. It really depends on which part of the community you mean, or even outside of the community ... People like Eric have had a big influence on business folks, which I certainly don't have.
LJ: What do you think is the most important addition or change needed by Linux in order for it to succeed further? In what direction does Linux development need to go? Where is Linux's future the brightest? What is the #1 biggest threat to Linux today?
Alan: Probably the biggest thing Linux needs now is better applications and user-space tools. We need to take Linux to the level where you can give it to your grandmother, and not expect a phone call back except to say "thanks". The biggest thing the kernel needs now is documentation.
I'm not sure what the threats to Linux really are. The biggest one is probably Linux fragmenting. I don't think that is going to happen in the mainstream, but we are already seeing a few vendors pulling that way in embedded space.
The app vendors and the users, I don't think, will tolerate a vendor going off at a tangent.
LJ: How do you feel about Linux's current popularity? Would you have preferred it stayed contained in the hacker community? Would it have survived on the fringes?
Alan: It was a bit of a surprise. On my first trip to Red Hat, they had about six people, and the new boy was this Donnie Barnes guy. Now they are heading for five hundred.
Linux would have survived on the fringes, I think. There has always been a market for things people can actually play with and tune.
LJ: Would it have survived without the IPOs and financial backing? What impact has the commercialization of Linux had? How do you feel about Linux profiteering and the people who make millions off of other people's volunteered efforts?
Alan: I'm working for a vendor. I get regular mail from people trying to find Linux-aware folks to hire. I think those who wrote code for fun have plenty of opportunity to reap rewards. Even when I wasn't working for Red Hat, it didn't bother me. I wrote it for fun, and the fact that people found it useful was a greater reward than money. We've made it possible to put computers into places that could never have afforded Microsoft products.
LJ: How can Linux compete with Microsoft in the desktop sector, and will we be able to hold the commercial sector if we don't take the desktop as well? Can we take the desktop without ruining the spirit of Linux by dumbing it down? Where will our next areas of growth and expansion be?
Alan: Trying to predict the desktop is hard. Firstly, I think it's safe to say that the PC desktop of today is probably the dinosaur of tomorrow. Most end users want simpler systems. They want to trade flexibility for ease of use, and power for size.
There will be plenty of people who choose the full PC, some because they enjoy it and some because they need all the power. Those, I suspect, are the minority.
The machines of tomorrow are mostly going to be web-oriented, or very mobile (or both). People will expect them to just work. Folks like Palm have taken the first stumbling steps in this direction, with huge success.
Linux is a good OS for building embedded systems with, and to be able to extensively customize. GNOME and KDE will give people a good battle on the desktop and beyond.
LJ: How do you feel about commercial applications being written for Linux, and proprietary software and protocols in general? Do you run Linux more for philosophical reasons or practical reasons? If something that appeared to be better came along, would people jump ship? Conversely, would we stay with Linux even if it somehow degenerated, took a wrong turn, or stopped progressing?
Alan: I don't believe open source works for everything. There are some cases where the ideas in the code truly have value, but not many. I don't currently use any proprietary software generally, except Netscape. And Mozilla is now within a hair's breadth of replacing that.
I like the flexibility and the control of free software. Most of my experiences with proprietary software have either been getting screwed as a user, or being part of a large company that had to threaten its suppliers with lawsuits to get service. Proprietary software could work, but not while software companies spend all their time and effort lobbying the U.S. government to be basically exempt from all reasonable law on quality and fairness to the consumer, instead of giving people what they want.
LJ: Do you think the community should support only open-source/free software? How would the community survive hard times if there were a lag or down time in the continuing success of the open-source methodology? Is the free software philosophy strong enough and with enough adherents to pull us through?
Alan: The real community consists of those who contribute - not just code, but bug fixes, documentation, etc. That community can survive a lot. Some of the rest of the Linux user base is certainly there because "it's cool", "it's not Microsoft" and for commercial reasons. It's up to the free software methodology to work out for those people. If it does, they will go that way.
LJ: How do you feel about the different licenses? GPL, LGPL, QPL, etc.?
Alan: The old Qt license was a problem. I don't see one with their current licensing. Too many licenses can be a problem, but the basic few we have now seem to fit a wide spectrum of beliefs well.
LJ: Is there a world outside of computers? Are you ever afraid that you'll wake up one day and feel you have wasted your life in front of a computer?
Alan: Most of what I am doing, even that involving computers, is about people and interacting with people. That's true for most computing use. People are using e-mail, IRC, messaging systems and web-based discussion systems a lot. It's about people communicating.
email: firstname.lastname@example.com


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The Red Bulls academy was in action at all age levels on the weekend of May 7-8 and completed their third consecutive undefeated weekend with a total record of 4-0-2.
This week, the academy teams took on Continental FC Delco and Seacoast United.
New York Red Bulls U-18 (2) vs. Continental FC Delco (2)
HANOVER, N.J. (May 8, 2016) – The New York Red Bulls came from behind to tie FC Delco, 2-2, in a windy Mother's Day afternoon game at the Red Bulls Training Facility.
New York got off to a slow start in the first half and found themselves behind by two goals at the break.
The Red Bulls rallied in the second half. The break through came in the 75th minute when Brian Saramago was tripped by the FC Delco goalkeeper. Saramago quickly got to his feet to convert from the spot for 16th goal of the season.
The second goal came 10 minutes later when Saramago flicked on a Christian Martinez pass for Barry Sharifi to run through and score for his sixth goal of the campaign.
The Red Bulls would push for the winner in a thrilling end to the game and went close on a number of occasions.
Matt Thorshiem's cross from left was flicked goal bound by Saramago, only to see the goalkeeper get his hand to it and the Delco defense scramble away the rebound. Rodrigo D'Andrea was next with a well-struck shot from distance that was tipped over the cross bar. The Red Bulls earned three corners in injury time, but could not find the elusive third goal.
"We had a poor first half that left ourselves in a hole," Man of the Match Sean Teixeira said. "But we came out in the second half much sharper and were able to create many scoring opportunities that lead to us leveling the game. It was encouraging for the team to be able to overcome a slow start and get the result."
Next up for Red Bulls U-18 is a trip to Seacoast United on Saturday, May 14 at 11 a.m.
Man of the Match: Sean Teixeira
Scoring Summary (Assists in parenthesis):
- FC Delco 30'
- FC Delco 36'
- NY: Brian Saramago (PK) 75'
- NY: Barry Sharifi (Brian Saramago) 85'
Matthew Rosenberg, Sean Teixeira, Mason Deeds (Matt Thorshiem, 72'), Cristian Martinez, Maxwell Aunger (Kevin O'Toole, 46'), Samad Bouthong, Jared Gilbey, Callum Johnson, Kyle Casey (Rodrigo D'Andrea, 46') Brian Saramago, Barry Sharifi
Subs not used: Matt Goodman, Vince Borden
New York Red Bulls U-16 (2) vs. Continental FC Delco (0)
HANOVER, N.J. (May 8, 2016) – The Red Bulls U-16s defeated Continental FC Delco on a windy Sunday, 2-0. With the win, New York remains unbeaten since suffering their only loss of the season in early October.
After a back and forth scoreless first half, the Red Bulls would now have the strong wind at their backs for the second half. They wasted no time attacking the Delco defense with several shots early on. The breakthrough came in the 60th minute with Omir Fernandez scoring off a pass from Chris Bermudez. Minutes later, Nick Schimbeno scored on a laser from 30-yards out to make it 2-0. The Red Bulls continued the barrage of attacks but the Delco goalkeeper was up to the challenge.
With the win, the Red Bulls U-16s improved to 16-1-4 on the season. New York will travel to New Hampshire next weekend to take on Seacoast United.
New York Red Bulls U-14 (1) vs. Continental FC Delco (1)
HANOVER, N.J. (May 8, 2016) – The Red Bulls U-14s played to a draw against FC Delco, 1-1.
New York scored in the 23rd minute to take the lead. Forward Jordon May was played in behind the FC Delco backline and played a great ball across the goalmouth for Alex Quezada to finish.
FC Delco equalized two minutes later, but the Red Bulls almost took back the lead in the 73rd minute when forward Scotty Taylor blasted a 25-yard shot off the crossbar.
The Red Bulls struggled to get a rhythm going in windy conditions and the game finished in a draw.
Lineup: Liam Bertrand, Samory Powder (Danny Ramm, 52'), Lucas Santos, Amadeo Chapru-tate 47'), Jonathan Ned (Sal Pliego, 72'), Jayden Reid, Conner Maurer, Peter Stroud, Danny Jara, (Sean Ryan, 72'), Jordon May (Scotty Taylor, 47'), Alex Quezada (Aziel Jackson 47'), Leo Hecht (Dylan Sullivan, 47').
Man of the Match: Peter Stroud (7)
Scoring Summary (Assists in parenthesis):
- NY: Alex Quezada 5 (Jordon May 1) 23'
- FC Delco 25'
New York Red Bulls U-13 (5) vs. Continental FC Delco (0)
HANOVER, N.J. (May 7, 2016) – The Red Bulls U-13 hosted FC Delco on Saturday and won, 5-0.
The teams entered halftime scoreless as both sides struggled to initially find a rhythm. After refocusing during the break, the Red Bulls came out flying in the second half.
Kyle Linhares finished his first of four goals just one minute into the half, as he clinically slotted home a nicely weighted through ball from Andrew Maia that beat Delco's back line.
Murat Calkap also finished off a nice individual effort inside the box as the game ended 5-0. Elliot Leinweber, Mike Malozemov and the back four combined to keep the shutout.
Lineup: Justin Weiss, Jayson Argueta, Kyle Linhares, Gabe Llanos, Aidan Borra, Matty Acosta, John Tolkin, Bryce Lebel, Hamza Shehata, Amir Daley, Elliot Leinweber
Subs used: Murat Calkap, Matt Agudelo, Andrew Maia, Dylan Estevez, Mike Malozemov, Ethan Layton, Anthony Bileddo
Scoring Summary (Assists in parenthesis):
- NY: Kyle Linhares (Andrew Maia) 41'
- NY: Kyle Linhares (Andrew Maia) 48'
- NY: Kyle Linhares (PK) 60'
- NY: Kyle Linhares (Matty Acosta) 61'
- NY: Murat Calkap 71'
New York Red Bulls U-12 – Blue (4) vs. Seacoast United (3)
HANOVER, N.J. (May 7, 2016) – The New York Red Bulls U-12 Blue defeated Seacoast United at the Red Bulls Training Facility, 4-3.
The win marks the team's third consecutive victory and propels the team to 12-1-4 on the season.
New York Red Bulls U-12 – White (8) vs. Seacoast United (4)
HANOVER, N.J. (May 7, 2016) – The New York Red Bulls U-12 White extended their winning streak to eight games on Saturday with a win against Seacoast United, 8-4.
The Red Bulls U-12 White are 12-3-1 on the season.


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Effects of Roflumilast on Insulin and Blood Sugar Levels in Prediabetic Overweight and Obese Individuals
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
|ClinicalTrials.gov Identifier: NCT01862029
Recruitment Status : Completed
First Posted : May 24, 2013
Results First Posted : September 4, 2018
Last Update Posted : September 4, 2018
- Study Details
- Tabular View
- Study Results
- Disclaimer
- How to Read a Study Record
|Tracking Information
|First Submitted Date ICMJE
|May 22, 2013
|First Posted Date ICMJE
|May 24, 2013
|Results First Submitted Date ICMJE
|July 26, 2018
|Results First Posted Date ICMJE
|September 4, 2018
|Last Update Posted Date
|September 4, 2018
|Study Start Date ICMJE
|May 22, 2013
|Actual Primary Completion Date
|July 25, 2017 (Final data collection date for primary outcome measure)
|Current Primary Outcome Measures ICMJE
|Original Primary Outcome Measures ICMJE
|The primary outcome in this study is changes in insulin sensitivity as measured by the stable isotope0-labeled tracer technique and FSIVGTT. [ Time Frame: 3 years ]
|Change History
|Current Secondary Outcome Measures ICMJE
|Not Provided
|Original Secondary Outcome Measures ICMJE
|The secondary outcomes are changed in beta-cell function, postprandial plasma incretin concentrations, circulating levels of adipokines, cytokines, and inflammatory markers, and alterrations in total body fat and lean body mass. [ Time Frame: 3 years ]
|Current Other Pre-specified Outcome Measures
|Not Provided
|Original Other Pre-specified Outcome Measures
|Not Provided
|Descriptive Information
|Brief Title ICMJE
|Effects of Roflumilast on Insulin and Blood Sugar Levels in Prediabetic Overweight and Obese Individuals
|Official Title ICMJE
|An Exploratory Study to Evaluate the Effects of Roflumilast on Insulin Sensitivity and Metabolic Parameters in Prediabetic Overweight and Obese Individuals
|Brief Summary
- Roflumilast is a drug used to treat chronic obstructive pulmonary disease (COPD). It is designed to help reduce lung inflammation. However, during testing, roflumilast also appeared to reduce high blood sugar levels in people with COPD and type 2 diabetes. Other tests showed that roflumilast also improved blood sugar levels in people who only had type 2 diabetes. Researchers want to see how roflumilast affects insulin and blood sugar levels in overweight or obese people who are not diabetic, but who have high blood sugar levels.
- To see how well roflumilast improves blood sugar and insulin levels in prediabetic overweight or obese individuals.
- Individuals between 30 to 65 years old who are overweight or obese (body mass index of 24.9 to 39.9 kg/m2) and have elevated blood sugar levels.
In the last week, participants will have a final follow-up visit.
|Detailed Description
|Resveratrol, a polyphenol most notably found in red wine has anti-aging properties in mice fed a high-fat diet; resveratrol protects against obesity and type 2 diabetes. Several clinical trials have been conducted to study the metabolic effects of resveratrol. Although these trials have used different subject groups (e.g. obese healthy, type 2 diabetics or older adults with glucose intolerance), they suggest that resveratrol may improve insulin sensitivity. However, the therapeutic potential of resveratrol is diminished by the fact that it has a very promiscuous target profile. In order to translate resveratrol biology into clinical application, it is helpful to identify the cellular target(s) of resveratrol that mediate the desired effects and to develop therapies specific for that target(s). Recently, we discovered that the metabolic effects of resveratrol appear to result from competitive inhibition of cAMP-degrading phosphodiesterases (PDEs), which increases cAMP levels. The cAMP-dependent pathways activate AMP-activated protein kinase (AMPK), which is essential for the metabolic effects of resveratrol. Inhibiting PDE4 with rolipram reproduces all of the metabolic benefits of resveratrol, including protection against diet-induced obesity and an increase in mitochondrial content, fat oxidation, physical stamina and glucose tolerance in mice. Based on results from cellular and preclinical studies, we hypothesize that PDE4 inhibition will ameliorate insulin resistance in pre-diabetic individuals. To test these hypotheses, we will conduct an exploratory study on the potential beneficial effects of roflumilast (Daxas (Registered Trademark)), a PDE4 inhibitor, on insulin sensitivity in pre-diabetic individuals.Each study participant will receive oral roflumilast (250 (micro)g, once a day for 2 weeks, followed by 500 (micro)g once a day for 4 weeks). At baseline and after the 6-week treatment period, we will assess insulin sensitivity (hyperinsulinemiceuglycemic glucose clamp technique, glucose clamp ). In addition, Beta-cell function, skeletal muscle mitochondrial function, body composition, and circulating adipocytokine profile will be measured at baseline and after treatment to evaluate potential changes that may be related to improvements in metabolic function. Vascular function is not only an indicator of insulin sensitivity, but is also important for glucose delivery and metabolism. If possible, vascular function will be assessed along with the other parameters at baseline and after treatment with roflumilast. Regarding vascular function, we may measure basal and insulin-stimulated brachial artery blood flow (large conduit artery assessed by Doppler ultrasound) as well as capillary recruitment in forearm skeletal muscle (small nutritive arterioles assessed by ultrasound with microbubble contrast). This study will explore whether roflumilast is effective at improving insulin sensitivity in pre-diabetic individuals. Results from this study may have important implications for the potential use of roflumilast in treating type 2 diabetes.
|Study Type ICMJE
|Study Phase ICMJE
|Phase 1
Phase 2
|Study Design ICMJE
|Allocation: N/A
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
|Condition ICMJE
|Intervention ICMJE
|Drug: Roflumilast
Selective phosphodiesterase 4 (PDE4) inhibitor
|Study Arms ICMJE
|Experimental: Roflumilast
Intervention: Drug: Roflumilast
|Publications *
* Includes publications given by the data provider as well as publications identified by ClinicalTrials.gov Identifier (NCT Number) in Medline.
|Recruitment Information
|Recruitment Status ICMJE
|Actual Enrollment ICMJE
|Original Estimated Enrollment ICMJE
|Actual Study Completion Date ICMJE
|July 25, 2017
|Actual Primary Completion Date
|July 25, 2017 (Final data collection date for primary outcome measure)
|Eligibility Criteria ICMJE
|Sex/Gender ICMJE
|Ages ICMJE
|30 Years to 65 Years (Adult, Older Adult)
|Accepts Healthy Volunteers ICMJE
|Contacts ICMJE
|Contact information is only displayed when the study is recruiting subjects
|Listed Location Countries ICMJE
|United States
|Removed Location Countries
|Administrative Information
|NCT Number ICMJE
|Other Study ID Numbers ICMJE
|Has Data Monitoring Committee
|U.S. FDA-regulated Product
|IPD Sharing Statement ICMJE
|Not Provided
|Responsible Party
|National Institutes of Health Clinical Center (CC) ( National Heart, Lung, and Blood Institute (NHLBI) )
|Study Sponsor ICMJE
|National Heart, Lung, and Blood Institute (NHLBI)
|Collaborators ICMJE
|Not Provided
|Investigators ICMJE
|PRS Account
|National Institutes of Health Clinical Center (CC)
|Verification Date
|February 26, 2018
ICMJE Data element required by the International Committee of Medical Journal Editors and the World Health Organization ICTRP


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I will be implementing the OpenGL SC standard for an Intel graphics card, but the 1.0/1.0.1 SC standards state that the internal format for RGB must be using 3 bytes (assuming it means RGB8, with 8 bytes each texel).
The Intel cards only store textures in 1, 2, or 4 byte increments per texel. The RGB they support is RGB5 (R5G6B5). When you use RGB8, it is stored as RGBA8.
It is fairly common for cards to only support the RGB565 format internally so I was wondering if the standard was intentionally trying to go against the grain. Currently, I will have to list this as an area where I am not in compliance with the speciification, but I think this will be an area many will not be able to comply with due to hardware restrictions.
Also, the 1.0.1 standard still references table 3.1 for internal formats, but should really reference 3.2 since that table has been renumbered.


text:
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text:
This is a normal response if you changed something on a battery driven device. So in case this is a baattery device, it should normally be written to the device the next time it wakes up automatically. Once in a while I have pushed the button write to device in the configuration screen.pierre2302 wrote:I get the message "Value Was changed to 240 but not Stored in device yet."
Check the presently configured wake up interval. If it is very long, you may consider to reinclude the device, and set the interval much shorter temporarily, while you are playing with other settings.


text:
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D3stiny_Sm4sher wrote:Ah, OK, I thought I'd been missing out on this but it looks like we're still waiting on that one to be finished.
Editing = time consuming.
Firelord Alex wrote:It did not happen because half the people didn't show up
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text:
A bit of casting news to share with you today. Here are the important bits:
- Jonathan Rhys Meyers (Match Point) is in negotiations to join The Mortal Instruments: City of Bones, the adaptation ofCassandra Clare'sYA fantasy novel.
- Xavier Samuel (The Twilight Saga: Eclipse) will join Emily Browning and Cam Gigandet in Catherine Hardwicke's indie thriller, Plush.
Hit the jump for more details on each picture.
First up from Heat Vision comes word that Meyers is in talks to join The Mortal Instruments: City of Bones as Valentine Morgenstern, a "powerful but insane Shadowhunter looking to make the world pure at any cost." The adaptation follows a young woman (Lily Collins) who discovers she's a Shadowhunter herself, descended from a sect of half-angel warriors who protect our world from demons. Written by Jessica Postigo and I. Marlene King, The Mortal Instruments: City of Bones also stars Lena Headey, Jared Harris and Kevin Zegers. TheHarald Zwart-directed picture is set to start shooting in Toronto later this month.
As for Plush, Variety reports on Samuel's addition to the cast. [Update: New details make no mention of a psychic psychologist, which had previously been reported.] They also have a few more plot details this time around. Browning plays a rock star on the rise who suffers a setback when her brother, a fellow band member, dies due to a drug overdose. Married with two children, her character seeks solace in a new guitarist (Samuel), instead of her husband (Gigandet). When their creative collaboration turns sexual, Browning's character fears for her family as she begins to realize her new partner may be a madman. Hardwicke will also produce Plush, which she co-wrote with Artie Nelson.


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Origin: Biblical / Hebrew
Meaning: "pleasant, sweet, delightful, beautiful."
Pronunciation: (NAY-ah-mah)
Nicknames: Nay, Naa, Nomi, Gnomes
Detail: The name Naamah comes from (naem) meaning be pleasant, sweet, delightful, beautiful. Derivatives are (noam), pleasantness, beauty; (naim), pleasant, sweet; (naaman), pleasantness; and (manammim), delicacies.
Could make a good alternative to the increasing in popularity Naomi, and with Noah also high in the charts, this name is on the good side of unusual.


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Wineke: Why gay rights win
The Boy Scouts of America organization is hoping to back off its unpopular stance against homosexuality by proposing to accept gay scouts but not gay scout leaders.
It will be interesting to see whether they can actually make the change. Scout troops are often sponsored by churches and churches still make up the center of anti-gay sentiment.
The proposed policy doesn't really make a whole lot of sense. Scout leaders tend to be former scouts. If you're going to change one part of the equation, why not the other?
But the bigger question, to me, is how did this nation go from being pretty much anti-gay to pretty much pro-gay. Minnesota, for example, just became the latest state to legalize same-sex marriage.
And, I think the answer is simple: Gay people have gone public about their gender identity.
Once they did that – and once their families became open about their gay and lesbian children and siblings – most of us could no longer avoid confronting the fact that we know gay and lesbian people and they are pretty much just like us.
I got a taste of this years ago when I lived in Brooklyn Heights, New York. Brooklyn Heights was, and is, a beautiful section of New York City featuring tree-lined streets and classic brownstone homes. It had been run down until homosexual men and women started moving in and restoring the homes.
I knew nothing about homosexuals before moving there. I pretty much assumed that gay men were effete and lesbians were mannish. Except that none of that seemed to be true of any of my neighbors. In fact, the main difference between them and me is that they watched sports on television and I didn't.
Elsewhere, gays and lesbians tended to stay in the closet. In some states, they could be arrested just for being gay. In most places, their employment prospects were limited.
And, as I look back on it, we had family friends who were almost surely lesbians. It just never occurred to us that they might be sharing the same beds.
Nor did I, nor do I, know a thing about the sexual practices of my heterosexual friends.
But once I realize that the only public thing separating my neighbor from me is that he likes guys or she likes gals, then it gets pretty hard to justify saying the neighbor can't legally marry, or be a parent. . .or lead a Boy Scout troop.
The more we know, the less we need to know. I predict we will have both gay marriage and gay scout leaders within the decade and I predict western civilization will be just fine.


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erm glaub das reicht für ut2k7What do you get for the graphics buff who has everything? How about Nvidia's Quadro Plex 1000, a racked collection of GPUs in their own box, together capable of rendering 80bn pixels every second and powering monitors with a combined resolution of up to 148 megapixels.
It doesn't come cheap, mind - prices start at $17,500. Nvidia has three models on offer. Two contain two Quadro FX 5500 GPUs, while the mid-range version, the Model II, has two Quadro 4500 X2 GPUs - ie. four graphics cores.
The Model I also contains a Quadro G-Sync board, while the Model II has two G-Sync cards. The Model III has two SDI (Serial Digital Interface) boards for broadcast-quality HD TV work.
Models I and III can do 32x SLI full-screen anti-aliasing, while the Model II goes up to 64x SLI FSAA. The Model II has 1GB of DDR2 graphics memory per GPU, while the other two machines have 512MB of GDDR 3 per GPU.
The machines are controlled from a PC or workstation - 32- or 64-bit, Windows or Linux - connected across a network. Nvidia reckons the boxes will interest not only content creators but folk doing scientific modelling and simulation work.
The Quadro Plex 1000 family is due to ship in September.


text:
A shooting that prompted a three-hour lockdown at McDaniel College early Sunday stemmed from a confrontation between a group of students and four men just off the Westminster campus, police said.
A group of male students was walking back to the campus from a Westminster restaurant some time before 2:45 a.m. when four men provoked them on Monroe Street, one of them displaying a handgun, police said. The students left the confrontation and returned to Whiteford Hall, a freshman dormitory, Westminster police said.
Moments later, shots were fired at the dorm through a second-floor lobby window, police said. No injuries were reported.
Those on the Westminster campus were ordered to stay in a safe location and away from windows about 3 a.m. College safety officials said they sent six alerts to the campus over the course of the lockdown and early investigation, with an all-clear notification sent at 6:23 a.m.
"The safety and security of our students is always paramount," McDaniel Vice President of Student Affairs and Dean of Students Beth Gerl said in a statement. "Thanks to campus-wide emergency preparedness education and the quick work of our highly-skilled Campus Safety and partnership with local law enforcement, we can report no student suffered physical harm."
The investigation is ongoing. Anyone with information about the incident is asked to call campus safety officials at (410) 857-2202.
Westminster police were meanwhile investigating a second incident on the campus reported just before the shooting. A student told police a gray minivan pulled up next to him as he walked along Pennsylvania Avenue, and three men jumped out and demanded his property. One of the men said he was armed with a knife.
The student ran to a friend's apartment and was not injured, nor did he give anything to the suspects, police said.


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Through the Grapevine: Texas harvest grape stomps
Texas harvest is in full swing, with plenty of opportunities to get involved and even get your feet dirty, if that's your thing. This is a busy time for wineries, especially in the well-traveled Hill Country, so it's best to check the websites and make reservations for harvest activities, if recommended. For a list of Hill Country wineries, visit texaswinetrail.com and wineroad290.com.
Order of the Purple Foot Grape Stomp
When: 10 a.m.-2 p.m. today, Saturday (sold out) and Aug. 12
Where: Dry Comal Creek Vineyards, 1741 Herbelin Road in New Braunfels
Cost: $130 per couple. Pre-registration and payment is required either online (drycomalcreek.com) or at the tasting room. No phone reservations, but you can call 830-885-4076 to be put on the waiting list for sold-out dates.
Info: Cost includes lunch, two keepsake glasses, two drink tickets and two T-shirts. New this year: Take an old dress from your closet to Trash the Dress and stamp it with your grape-stained foot. Couples will compete — one stomps while the other collects — to see who can produce the most juice.
23rd annual Grape Stomp
When: Aug. 18 and 25
Where: Fall Creek Vineyards, 1820 County Road 222 in Tow
Cost: Free grape stomp. Reservations available for celebrity chef menu at 11:30 a.m. and 1 p.m., $22; patio lunch also available with reservation, noon-2:30 p.m., $12.75.
Info: Tour the winery, taste samples, and enjoy the patio. There will be a playhouse, face-painting and hayrides for the kids. Call 325-379-5361 or visit fcv.com/Grapestomp.html for more information.
10th Annual Grape Stomp
When: 11 a.m.-4 p.m. Aug. 18 and 25; 1-4 p.m. Aug. 19 and 26
Where: Texas Hills Vineyard, 878 Robinson Road in Johnson City
Cost: Stomping is free; T-shirt for sale.
Info: Enjoy the view of the vineyard from the new patio with a bottle of wine. Food will be available for purchase from Stout Pizza Truck on Aug. 18 and Crepe Nation truck on Aug. 25. Visit texashillsvineyard.com or call 830-868-2321 for more information.
16th Annual Grape Stomp
When: 10 a.m.-6 p.m. Saturdays and noon-6 p.m. Sundays Aug. 25-26 and Sept. 1-2
Where: Becker Vineyards, in Stonewall
Cost: Free, souvenir T-shirts for sale
Info: This grape stomp celebrates the end of harvest. Smokin' Willies Smoked Meats will be serving food for purchase, and there also will be live music.
Jennifer McInnis is the wine and spirits writer for the San Antonio Express-News. Follow her on Twitter @JenMcInnis or email email@example.com.


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Each month the industry produces hundreds of great sites and Design Fridge proudly showcases them in it's css gallery. Some designs standout from the mix for their original concept and the quality of their production.
The following 10 designs are outstanding examples of design built to current web standards, and each one deserves recognition.


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SPY's Controversial Billboard is Happily Replaced
How billboard puts smiles on faces
CARLSBAD, Calif.—SPY's controversial Encinitas, CA billboard was replaced today by a new message in order to continue on with its Happy Lens™ campaign. Last week, SPY's billboard—which said "Happy to Sit on Your Face"—was taken down after a few complaints about its double entendre. It now reads "Happiness is Coming…" and it hit the Encinitas skyline early this morning—much to the delight of an overwhelming majority of local residents who loved the original board, hoping it would be re-installed.
"We're happy that the billboard is up again, and that SPY is permitted to tell everyone that the Happy Lens™ will be arriving soon," says SPY Marketing Director Devon Howard. "We have several months to go leading into the Happy release, so we're hoping this billboard sticks around for longer than the last one did (a week)."
The San Diego based eyewear brand, SPY, has engineered a revolutionary new patent pending lens technology—the Happy Lens™—which harnesses the science behind light therapy. The censored billboard was the first nod toward the Happy Lens™ launch in February 2013. Upon receiving feedback from a small number of local citizens about SPY's Happy Hwy 101 billboard, the "Happy to Sit on Your Face" message was taken down and in its place stood an old gun show ad.
The original "Happy" campaign launch billboard was removed on the morning of September 6, where locals were on hand to express their support of the billboard message and demand it be reinstated. In case you missed the coverage, see what all the noise was about here: http://www.youtube.com/watch?v=h9X0jc93ME4.
For more information about SPY, log-on at www.spyoptic.com, www.facebook.com/spyoptic<http://www.facebook.com/spyoptic>, Twitter @spyoptic<http://twitter.com/#%21/spyoptic> and @spyoptic on Instagram.


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Home > A. Molecular pathology > Variants-Mutants > KIT-D816V
Tuesday 29 November 2011
- The dasatinib is a dual inhibitor of the src and abl tyrosine kinases.
- It was approved by the Federal Drug Administration for the treatment of imatinib mesylate-resistant chronic myeloid leukemia.
- Dasatinib inhibits juxtamembrane domain mutant KIT-D816V autophosphorylation and KIT-dependent activation of down stream signaling important for cell growth and survival of neoplastic cells.
- Additionally, dasatinib induces apoptosis in mast cell and leukemia cell lines expressing KIT-D816V.
- Dasatinib has in vitro and in vivo efficacy in SM-AML patients with KIT-D816V mutation.
- Along with chemotherapy, dasatinib should be considered in these patients particularly if they cannot undergo allogeneic stem cell transplantation for this poor prognostic AML. (18986703)
See also
SRC pathway
SRC pathway inhibitors
Talpaz M, Shah NP, Kantarjian H, et al. Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias. N Engl J Med 2006;354:2531-2541.
Chemotherapy and dasatinib induce long-term hematologic and molecular remission in systemic mastocytosis with acute myeloid leukemia with KIT D816V. Ustun C, Corless CL, Savage N, Fiskus W, Manaloor E, Heinrich MC, Lewis G, Ramalingam P, Kepten I, Jillella A, Bhalla K. Leuk Res. 2009 May;33(5):735-41. PMID: 18986703
Weisberg E, Manley PW, Breitenstein W, et al. Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl. Cancer Cell 2005;7:129-141.


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I love this wedding in all its pristine and natural beauty. The beautiful and carefree barefoot bride, chic and casually dressed entourage, nonchalant reception decor and the breathtaking charm of Bohol — all yours for the taking today.
I wouldn't be able to translate into words the silent spectacle of Andrew and Jay's wedding. You just have to see for yourselves the wonderful photographs taken by the extremely talented Paopao Sanchez in order for you to enjoy and absorb the beauty of this bohemian beach wedding.
It's quite rare that I am at a loss for words. This is one of those rare occasions. So I wouldn't hold you any longer, cherries. Fall in love and be ready to be swept away. As Paopao puts it, "Gorgeous couple, gorgeous wedding!" Enjoy viewing! 🙂
The Photo Gallery:
The Dream Team:
Photography: Paopao Sanchez Photo | Videography: Superseven | Ceremony and Reception Venue: Bohol, Philippines | Coordination: Supreme Weddings | Make up: wayofthebunny.com


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Top 100 Language Lovers 2010
The Top 100 Language Blogs is probably the largest language blog competition hosted annually by bab.la and Lexiophiles. It is aimed at finding the best blogs related to languages and awarding language-loving bloggers. This year we had the most nominations ever, counting 495 blogs from all over the world. After our previous competitions in 2008 and 2009 we are proud to announce the 2010 winners. A big thank you to all participants for sharing their enthusiasm and knowledge with the world. Keep on blogging!
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