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Submitted by: Donald Hank
The Global Elite Are Very Clearly Telling Us That They Plan To Raid Our Bank Accounts
"If there is a risk in a bank, our first question should be 'Okay, what are you in the bank going to do about that? What can you do to recapitalise yourself?'. If the bank can't do it, then we'll talk to the shareholders and the bondholders, we'll ask them to contribute in recapitalising the bank, and if necessary the uninsured deposit holders"
"It will force all financial institutions, as well as investors, to think about the risks they are taking on because they will now have to realise that it may also hurt them. The risks might come towards them."
Mr. Dijsselbloem's style contrasts with that of his predecessor, Jean-Claude Juncker, Luxembourg's prime minister, who spoke in a low mumble at news conferences and was expert at sidestepping questions. Mr. Juncker once even advocated lying as a way to prevent financial markets from panicking—as they did Monday after Mr. Dijsselbloem's comments."When it becomes serious, you have to lie," Mr. Juncker said in April 2011. "If you have pre-indicated possible decisions, you are feeding speculation in the financial markets."
"A tax rate of 15 percent on financial assets would probably be enough to push the Italian government debt to below the critical level of 100 percent of gross domestic product"
People who rob old ladies in the street, or hold up security vans, are branded as thieves. Yet when Germany presides over a heist of billions of pounds from private savers' Cyprus bank accounts, to 'save the euro' for the hundredth time, this is claimed as high statesmanship.It is nothing of the sort. The deal to secure a €10 billion German bailout of the bankrupt Mediterranean island is one of the nastiest and most immoral political acts of modern times.It has struck fear into the hearts of hundreds of millions of European citizens, because it establishes a dire precedent.
As it stands now, nowhere in Cyprus accepts credit or debit cards anymore for fear of not being paid, it is CASH ONLY. Businesses have stopped functioning because they cannot pay employees OR pay for the stock they receive because the banks are closed. If the banks remain closed, the economy will be destroyed and STOP COMPLETELY. Looting, robberies and theft are already on the rise. If the banks open now, there will be a massive run on the bank, and the banks will FAIL loosing all of its deposits, also causing an economic crash. TONIGHT there are demonstrations at most street corners and especially at the parliament building (just 2 miles from me).Many are thinking that the ECB and EU are allowing Cyprus to fail as a test ground for new financial standards.Just wanted all you guys to know the real story of whats going on here. Prayers are appreciated (although this is very interesting to watch) many of my local friends have lots of money in the banks.
"The central government's interest bill surged 15 percent last year to 26 billion euros, while tax receipts slumped 21 percent. The cost of servicing debt represented 30 percent of the taxes collected at the end of December, up from 20 percent a year earlier."
At the end of the day, the reason Europe hasn't been fixed is because CAPITAL SIMPLY ISN'T THERE. Europe and its alleged backstops are out of money. This includes Germany, the ECB and the mega-bailout funds such as the ESM.Germany has already committed to bailouts that equal 5% of its GDP. The single largest transfer payment ever made by one country to another was the Marshall Plan in which the US transferred an amount equal to 5% of its GDP. Germany WILL NOT exceed this. So don't count on more money from Germany.The ECB is chock full of garbage debts which have been pledged as collateral for loans. If anyone of significance defaults in Europe, the ECB is insolvent. Sure it can print more money, but once the BIG collateral call hits, money printing is useless because the amount of money the ECB would have to print would implode the system.And then of course there are the mega bailout funds such as the ESM. The only problem here is that Spain and Italy make up 30% of the ESM's supposed "funding." That's right, nearly one third of the mega-bailout fund's capital will come from countries that are bankrupt themselves.What could go wrong?


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Desktop as a Service
Stop wasting money on continuously upgrading and maintaining your PCs and take advantage of the flexibility and scalability of the cloud by running all your desktops remotely.
Your staff will be able to access their desktop from anywhere in the world (depending on the security settings you chose). Enable and disable applications as needed, on a monthly basis. Let us manage all the hardware and all the security, backups, monitoring and software installations and updates.
BitCloud can provide custom server environments with full control of what applications each user has access to and tightly and securely integrate the remote desktops into your existing business network.
Scale from 5 to 500 desktops in a matter of minutes if needed, with almost instant access to the full suite of Microsoft office, database, productivity and management software.
For further information on BitCloud's Virtual Desktop environment, please contact our sales team on 1300 932 248 or via our contact form.

subset: commoncrawl


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Deluxe Crib Rental Package
Do you want to walk the beach with your child AND be able to stroll easily through downtown shops? This is the package for you! Rent a full-size crib, single jogging stroller, and high chair, and receive a Kelty Kids child-carrying backpack for FREE!
Traveling babies visiting Maine and New Hampshire never slept so well! Sealy crib mattress, fitted mattress pad and Magnolia organic fitted sheet included!
Sturdy, wooden crib with non-drop sides. JPMA certified, fully compliant with all current CPSC safety standards, and certified as an ASTM 2710 commercial crib. We set up and make up the crib for you at your equipment delivery destination!
Posted by Unknown on 10th Sep 2015
The package comes fully loaded for all needs. The crib was comfortable and they delivered on time.
Posted by Lisa Case on 2nd Sep 2015
We have rented from Ciao Baby Equipment Rentals a number of times in Southern Maine and have always had a fantastic experience. The gear is always very clean and in great shape, and they are so nice and easy to work with. We would highly recommend them!


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Customer service: (+33) 01 78 09 93 71 (Wednesday and Thursday 14h-18h UTC+1)
By clicking on the link below and seizing the 13 ciphers number we gave you in our confirmation mail:
standard airmail service (colissimo)
Fedex priority 24 hours delivery service:
For parcels weighing more than 71 Kg or large volume, specialised carrier are needed and you can join us by mail at:
Don't forget to give your name, address and order number:
Quality products and genuine certified
Prices lower than market ones
Free delivery at pick-up store (in France) from 100€
Respect of your liberties and security
Saab passionates
answer your questions
+33 178.099.372 (Wed. and Thur. 14h-18h UTC+1)
International customers are welcome ! You can use the english version of our website by clicking the union flag.
ˇLos clientes internacionales son bienvenidos ! Puedes usar la versión espańola de nuestro sitio haciendo clic en la bandera respectiva.


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Zoom @ WSU
WSU is replacing Bb Collaborate with Zoom meetings, starting January 1, 2018.
Zoom should prove to be a much more versatile and easy-to-use solution for digital learning at WSU because each user has the capacity to create and host their own online meeting. Zoom uses username and password authentication, and WSU's partnership with Zoom enables a single-sign-on option, meaning each valid WSUID/password combination functions as a Zoom ID/password.
The functionality and feel of Zoom compared to Collaborate will be quite similar: users meet in virtual meeting rooms in real-time, connect via camera, microphone, keyboard, screen sharing, whiteboard, etc. Each meeting has one or more "Hosts" and one or more "Participants." Hosts have control over the available tools in the meeting environment, as well as the overall look, feel, and function of the meeting.
Every Zoom account holder at WSU receives their own permanent, personal room for meetings, or they have the ability to generate a random, one-time URL to use for an instant meeting or a scheduled meeting in the future. Because of the multiple possibilities for meeting rooms/URLs, the host of a Zoom meeting must ensure that participants know the correct time and "place" for attending the meeting. Invites can be sent by email, course messages, or Blackboard announcement, and the meeting room ID can be shared as a URL accessible by any browser.
Zoom works via browser plug-in and/or free installable app, across desktop and mobile platforms (Windows, Mac, Android, iOS) and all browsers. (Though Google Chrome and Mozilla Firefox tend to work best.) The bottom of the wichitastate.zoom.us page contains a link to the downloads page, or you can simply browse to wichitastate.zoom.us/download. There, you'll the find options for the desktop app as well as mobile apps for iOS and Android.
Finding Your Personal Meeting ID
Zoom Wording for Syllabus or Course Announcement


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The Acoustical Music of Danimal on the "Back Porch" on Station Street
- 29 E. Station Street
- Chattanooga, TN 37402
- Presented By: Comedy Catch at the Choo Choo and Backstage Bar
- Location: Comedy Catch at the Choo Choo and Backstage Bar
Recurrence: Recurring weekly on Tuesday
- Time: 7:00 PM to 10:00 PM
- Price: $
- Phone: (423) 629-2233
- Visit Website
Local artist Danimal Pinson influences include bands such as Flaming Lips, Radiohead, My Morning Jacket, The Beatles, Sigur Ros, Wilco, Foo Fighters, Red Hot Chili Peppers, and more you are sure to find music that will hit you right in the chest. His music heavy on the songwriting process and you will find that as you move through each song. Full melodic and lyrical focus shine through the music with a solid foundation in rhythm that creates the primary characteristic which this music has been known for.


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LEED certification is the hallmark of a green building and these structures are built with a variety of green products that help towards achieving LEED certification. One of these green products is iCrete's specially formulated concrete; the concrete is not only sustainable but it is stronger than traditional concrete.
>ICrete products are being used in various construction projects across the nation including the Freedom Tower One World Trade Center in New York City. The company has now joined forces with a leader in West coast LEED building construction, California-based Webcor Builders.
Webcor Builders has been in business for decades and has had their hand in some of California's most prestigious green building projects including the LEED Platinum certified California Academy of Sciences. Webcor is a member of the U.S. Green Building Council and "earned more revenue in 2007 from LEED-qualifying buildings than it did from traditional buildings, and in 2008 the trend for increased LEED revenue continued." Source: PR Newswire
Webcor is now teaming up with iCrete to offer clients the use of "a significantly stronger concrete that optimizes raw material, is easier to work with, and protects the environment with reduced greenhouse gas emissions." Source: iCrete
Green products plus a green builder equal certified green buildings.


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Chicken Freezer Meals|This Is Why I'm Full
Below you will find links to five different Chicken freezer meals that we will be featuring as we cook them! As I have said all week, these delicious recipes were made 1 each day for a week in our house, the hubby and I both loved them and we hope you will too!
Let us know what you think of these chicken freezer meals and comment below with any questions/suggestions! Be sure and sign up for our Newsletter where we will be posting and sending out recipes we are going to make and giving you the opportunity to give us suggestions for what we should make next! Enjoy!
Crock Pot Fancy Italian Chicken


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- Sunday School Material
- >
- Sunday School Publishing Board
- >
- SSPB Faith Building Blocks Teachers Guide(Toddlers to Grade 1)
SSPB Faith Building Blocks Teachers Guide(Toddlers to Grade 1)
per item
(SUMMER QUARTER) Faith Explorers Upper Elementary Activity Book is formatted to help reinforce the Bible lesson to this age group. The activities are age-appropriate and directly connect with each lesson in the Bible study book. The students will be challenged through a variety of activities, such as word searches, crossword puzzles, unscrambling activities, "True or False?" activities, and more.


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The day starts with bird watching near the shoreline marshes of Ziway, followed by a slow cruise around the nesting grounds of Tulu Simbero, which means Bird Island in the local Oromo language. Visitors can view the island of Gelila from the boat. The craggy rocks of the island are home to its sole residents, who live in a small hut by the shore. Next visitors will journey across the golden lake to search out the lake's shy and elusive hippos. Since the hippos have a few favorite basking spots in the lake, the tour will varying depending on the time of year and the hippos habits.
- Spot rare and endemic birds in the marshes and forests.
- Catch glimpses of the lake's shy hippos basking in the water to escape the African sunshine.
Sample Itinerary - 3-4 Hours
- 9:00: Depart from Ziway to Bird Island
- 9:30: Arrive at Bird Island to view native birds in their habitat
- 10:15: Search for the elusive hippo at their favorite basking spots
- 11:30: Return to Lake Ziway shore
Custom itineraries can be arranged for the morning or afternoon. Hippo viewing make take longer than listed.
What to Bring
- Walking boots or shoes
- Sun screen, sunglasses, and hat
- Insect repellent
- Light rain jacket
- Bottled water
- Binoculars
- Gratuities for guides
- Waterproof bags for cameras and other equipment
To Book Directly
Manager: Firafes Nebi
Call +251 927 340 309
To Book through a Reservation Agent
Call: +251 550 8870 or +251 551 0168
For Assistance arraning full tours including lodging and transportation book through one of the participating tour operators.


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Hi guys and welcome to the Mondragon Sniper. The Mondragon rifle refers to a few rifles
designed by Mexican artillery officer general Manuel Mondragon, however it was not made
on the other side of that little wall that somebody want to build. It was manufactured in Switzerland by a company
called SIG and it was even used by the Germans during World War 1. Let's go over to the stats because that
is what it's all about. One single bullet will cause 40 maximum damage,
after 26.5 meters this damage will drop and it will settle at 35 damage at 51.5 meters. Wait a minute didn't we hear this before? The damage model is an exact copy of the Selbstlader. I will compare those 2 guns later in this
video so that you can decide for yourself which gun is better for your playstyle. The Mondragon can fire 257 round per minute
and it will need 3 bullets to kill your next favorite victim. The time to kill is 0.469 second and at 20
meters this time to kill will become 0.492 seconds. The Mondragon has a muzzle velocity of 800
meters per second which is pretty good. When you first deploy on the battlefield you
will start off with 10 bullets in your magazine and you will also get another 70 for later. It is a medic class gun but it's basically
a sniper rifle and that is why we don't have an empty reload time or a reload time
with bullets left. Instead we have a single bullet reload time
of 0.567 seconds and a strip clip reload time of 1.133 seconds. Just make it easy for yourself and remember
0.6 seconds for one bullet and 1.1 seconds for 5 at the same time because that is the
strip clip size. It is still a medic class weapon so it has
the benefit of having a deploy time of 0.7 seconds. And like every other gun in battlefield 1
it has a standard bullet drop of 12 meters per second squared. Let's unlock and modify our weapon first,
you can choose between a beam, cross, chevron or post reticle and a 4 times magnification
is the biggest one you can select. And then there is the bayonet but I'm sure
that you already know what to do with that thing. Let's compare the Mondragon with the Selbstlader. They both have the same damage model, but
what else do they have in common? The first thing that you will notice when
you are fighting and killing on the battlefield is that the Selbstlader has a slower rate
of fire. It can only fire 224 rounds per minute compared
to 257 and that is 15 percent slower. They both need 3 bullets to kill but the Mondragon
is able to kill faster due to the difference in fire rate. It will only need 0.492 seconds compared to
0.561 seconds at our 20 meters reference point. The muzzle velocity is exactly the same for
both of them. The Selbstlader has a proper reload time,
it will take you 3.4 seconds for an empty reload and only 2.3 for a reload with bullets
left.The deploy time is 0.7 seconds which is standard for all medic class primary weapons. The Selbstlader has a bigger magazine size
of 26 bullets compared to only 10 for the Mondragon, which means that it will be easier
to kill a lot of people in a short period of time but it will take longer to kill one
single guy. This basically sums up the biggest difference
between these 2 very similar guns. I mentioned that this gun is basically a sniper
rifle, but don't take that too literally. For sniper rifles it pays off to hold your
breath so that you can steady your scope. This will make it easier for you to get another
headshot. This won't work for the Mondragon. You can't hold your breath when you use
this gun, so don't bother pressing that button to steady your scope. It does come with a bipod and this has the
usual benefits. It will eliminate the scope sway and it will
reduce the recoil dramatically. This will make it easier for you to aim directly
at your enemy's eye ball for that ultra clean headshot. I had a lot of fun using the Mondragon sniper
and what I am about to say now is my personal opinion. When I was recording the footage so that I
could make this video for you, I first started playing with the Mondragon and when I had
enough footage I started playing with the Selbstlader. The first big thing that I noticed was how
much longer it took for the Selbstlader to kill. The difference is only 0.069 seconds at 20
meters, and you might think that this is nothing but it's big enough for you to notice. I first thought that I was biased somehow
because I just played a lot with these 2 weapons so to rule that out I made one of the hardest
decisions in my life and this may come as a shock but I decided not to play Battlefield
1 for 2 days, I mean I was as surprised as you that anyone is able to knowingly not play
Battlefield 1 for 2 days, and just to be sure I already booked an appointment in a detox
clinic and I signed up for the next AA meeting for gamers but strangely enough I survived. So I played Battlefield again, and I notice
the exact same difference. So I will always prefer the Mondragon over
the Selbstlader. On top of that the Mondragon just feels right. But that is just me, you will have to make
that decision for yourself. I just hope that I was able to give you all
the information that you need so that it will be easier for you to make that life changing
decision. This was FOG of GAMING, thanks for watching
and I will see you on the Battlefield.


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Technology to ease library search bumps. It is a slow news day in Mount Pleasant, Michigan. I can tell because my library got featured on the front page of the local newspaper today. The Morning Sun has this article which explains some of the recent innovations we have implemented here including a new document delivery system and our link resolver.
I like free publicity like this. It is also nice to see library staff such as Krista Graham, Anne Marie Casey, and Pat Barbour quoted in the paper.
From the site:
In the information age, access to information is only one part of the equation.
Speed and ease of access also are critical to meeting the demands of the modern consumer.
Central Michigan University's Charles V. Park Library is meeting those demands with two new programs that are designed to remove some of the roadblocks in the information superhighway.
ILLiad, a new interlibrary loan system that debuted March 6, and Find It!, a new tool for searching the library's collections that opened on Feb. 20, will move both systems to a more Web-based approach, according to university officials.


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JCB Select is our approved used machinery scheme designed to highlight machines which meet our tough criteria. JCB Select approved used machines are low in age and service hours, and benefiting from complete service histories and oil analysis checks.
We are so confident of our JCB Select machines that each and every one comes with a six month warranty – the first three months being covered comprehensively by PremierCover.
How it works…
Each JCB Select Approved used machine will have passed a thorough inspection and meet the following:
- Backhoe Loaders & Telehandlers – less than 4 years of age and 1,000 hours per year
- Excavators & Wheeled Loading Shovels – less than 4 years of age and 1,500 hours per year
- Any major components worn less than the set tolerance will be replaced with genuine JCB parts
- Undercarriage and tyres will not be less than 60%


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From the design of the first breathing regulator for Project Mercury, to a full suite of hardware and cutting-edge pneumatic subsystems for the ISS, Cobham has engineered some of the most complex, challenging space components in existence today. Cobham builds ultimate reliability into life support...
Many of the world's best known aircraft, including the F-35 and all Airbus platforms, feature Cobham technology. From internet in the sky through to jamming and missile guidance for the latest fighter aircraft, Cobham has an innovative suite of avionics, communication and navigation products for an...
From lightweight composite CNG tanks for automotive, to wireless coverage in the world's tallest building, Cobham has a variety of land based solutions for commercial and defence applications. Our advanced Ground Penetrating Radar detection, and secure communications support security forces and...
Cobham's maritime communications provide reliable communications in the toughest maritime conditions. We provide satcom and radio for the Volvo Ocean Race and microwave and radar technology for the AEGIS class cruiser. Cobham also offers an innovative range of safety and survival equipment, includi...
Game changing Aerial Refuelling Simulation Technology reduces extent of flight testing.
Cobham's Air-to-Air Refuelling (AAR) systems and modelling expertise has been used by the UK MOD to help achieve F-35 receiver clearance for mid-air refuelling from RAF Voyager. This is the first time that AAR modelling and simulation has been applied to the AAR Clearance process for a receiver aircraft and represents a significant step forward in this field.
Henry Clarke, Cobham's Simulation and Modelling Manager explains:
"We use modelling to help our customers test the performance and boundaries of our AAR equipment in a highly accurate and realistic way. Our aim is to provide them with enough substantiated evidence that they can minimize the number of flight trials needed to test the equipment thus saving a great deal of time and cost, as well as reducing pilot and aircraft risk"
"To support the MOD we validated our High fidelity AAR system model against existing flight test results and were then able to accurately reproduce the refuelling environment for the Voyager and F-35. Within this simulated reality, we were able to thoroughly test the performance of the Aircraft AAR systems across the whole refuelling envelope."
Cobham provides the Wing Air Refuelling Pods and Centre-line Refuelling Systems on the RAF Voyager as well as the probe on the F35B (STOVL variant) and F-35C (carrier variant).
The most capable critical control solutions for extreme environments.
As the world's leading supplier of critical control solutions, we help our customers to increase the safety and mission capabilities of their personnel and equipment in extreme environments.
Our proven and trusted solutions in air-to-air refuelling, life support and weapons carriage, deliver assured performance and class-leading through-life costs that enable our customers to bring complex projects to market quickly, and with minimal risk.
Cobham offers an innovative range of technologies and services to solve challenging problems in commercial, defence and security markets, from deep space to the depths of the ocean.
Charles Harrowing
Head of External Communications
+44 (0) 7720640137
Wimborne, United Kingdom: Rafael Advanced Defence Systems and Cobham Mission Systems (CMS) have agreed to a non-exclusive arrangement ...
The integrated O2 system features SureSTREAM™ Concentrator.
Smart Electronic Regulator will auto-adjust oxygen dose based on pilot physiological cues.


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FlexiPDF 2017 Professional 1.05 Download Free With Crack new version This is a versatile software to edit, create, delete, modify PDF documents to add text, images etc is as easy as a Processor of documents like word, notepad etc besides being able to export them to these same ones and much more, the software is available for Download complete in different languages with Spanish besides that it includes the Portable with its medicine Crack, continues seeing all the information Such as the features, description and images of SoftMaker FlexiPDF 2017 Professional 1.05, comments if you have been useful or simply thank, share and you may also want to see another alternative previously published that is Master PDF Editor.
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- Download SoftMaker FlexiPDF 2017 Professional 1.05
Description of the program
Edit PDF files just as easily as a word processor. With FlexiPDF, creating, editing and commenting on PDF files is as quick and easy as exporting them for later editing in TextMaker or Microsoft Word. FlexiPDF always offers excellent results, whether to enter or edit text and images, rearrange the layout or reorder the pages of a PDF file. FlexiPDF converts your PDF files into text documents that can be edited with TextMaker and Microsoft Word. Professional FlexiPDF also uses OCR to convert scanned pages into editable PDF and searchable files. FlexiPDF is the indispensable tool for anyone who works with PDF files.
• Built-in printer driver for creating PDF files from within all Windows applications
• Edit text in paragraphs and pages, as in a word processor
• Insert, move, delete pages; Insert pages from other PDF files
• Insert, move, erase images and drawings
• Ability to multi-language spell checker and automatic splitting
• insert comments, drawings, stamps
• Export PDF files for editing in TextMaker or Microsoft Word
• Export to HTML and image formats such as JPEG, TIFF and PNG
• Convert PDF files to ePUB ebook format
• Fill interactive and static forms
• Find and replace text and fonts
• find and replace hyperlinks
• Search and replace through files
• Create photo albums using simple drag and drop
• Page number, headers and footers, watermarks
• text export for translation with CAT software as Trados or memoQ
Function • OCR to convert scanned pages to editable and searchable PDF files
• Write confidential content
• Protect PDF files with secure AES encryption
• Control changes: the automatic highlighting of changes in text color
2346 Improving access to scanners through TWAIN
2600 Improved access through WIA scanners
2564 scanned pages sometimes looked like black rectangles.
2.489 paste from e-mail clients and fixed web browsers
2516 crash when creating portfolios
2515 Enhanced PDF Compatibility: Incorrect characters are displayed.
2540 Improved processing of corrupted PDF files
2532 crash when opening restricted form PDF
2551 enhanced character spacing with certain PDF files
– bug fixes


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Just a note to remind everyone that the Ye Olde Book and Collectibles Sale is this week:
10/25 Thursday 5pm-7pm – Members Only Preview Sale (Not a member, join at the door.)
10/26 Friday 10am-5pm
10/27 Saturday 11am-4pm
Please come and see what we have. Christmas is coming and you might be able to find a special gift for a friend or just for yourself.


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Boston, MA - Ebola virus (EboV) is the cause of sporadic outbreaks of highly fatal infections in Africa that are unpredictable in onset and rapid in progression. There is no effective vaccine or therapy for EboV infection. To address this problem, researchers at Brigham and Women's Hospital (BWH) used a robotic method developed by their colleagues at the National Small Molecule Screening Laboratory at Harvard Medical School to screen tens of thousands of compounds and identified a novel small molecule derived from benzylpiperazine adamantyl diamide that inhibits EboV entry into cells by more than 99 percent. Further studies at the United States Army Research Institute for Infectious Disease at Fort Detrick, MD verified that the newly identified entry inhibitor blocked cell-cell transmission of the virus. They used the inhibitor as a probe to investigate the EboV infection pathway and found that the target of the inhibitor is the cell protein Niemann-Pick C1 (NPC1). This research is published in the August 25, 2011 issue of Nature.
"In 2005, we showed that digestion of the glycoprotein on the surface of EboV particles by the host cell protease cathepsin B is a critical step in infection, but we knew that there was something else at play. Identifying the EboV inhibitor led us to the discovery that NPC1 is the conduit through which the virus is able to breakthrough cell membranes and infect host cells," said James Cunningham, MD, senior author of the paper and researcher in the Division of Hematology at BWH.
Combined with the results of previous studies of the virus glycoprotein structure and function, these findings indicate that EboV infection proceeds by sequential steps in which cathepsin B removes the protective top of the EboV glycoprotein and exposes the critical region that binds to NPC1 and triggers entry of EboV particles into cells.
"Our findings show that EboV infection has features in common with other pathogenic viruses including HIV and SARS that also utilize two host proteins to breakthrough cell membranes and infect host cells," said Cunningham. "It is interesting that NPC1 is critical for the uptake of cholesterol into cells, which is an indication of how the virus exploits normal cell processes to grow and spread. Small molecules that target NPC1 and inhibit EboV infection have the potential to be developed into anti-viral drugs."
This research was funded by a grant from the New England Regional Center of Excellence for Biodefense and Emerging Infectious Diseases (NERCE) at Harvard Medical School.
Brigham and Women's Hospital (BWH) is a 793-bed nonprofit teaching affiliate of Harvard Medical School and a founding member of Partners HealthCare, an integrated health care delivery network. BWH is the home of the Carl J. and Ruth Shapiro Cardiovascular Center, the most advanced center of its kind. BWH is committed to excellence in patient care with expertise in virtually every specialty of medicine and surgery. The BWH medical preeminence dates back to 1832, and today that rich history in clinical care is coupled with its national leadership in quality improvement and patient safety initiatives and its dedication to educating and training the next generation of health care professionals. Through investigation and discovery conducted at its Biomedical Research Institute (BRI), BWH is an international leader in basic, clinical and translational research on human diseases, involving more than 900 physician-investigators and renowned biomedical scientists and faculty supported by more than $537 M in funding. BWH is also home to major landmark epidemiologic population studies, including the Nurses' and Physicians' Health Studies and the Women's Health Initiative. For more information about BWH, please visit www.brighamandwomens.org


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Search the Community
Showing results for tags 'sunsets'.
Found 2 results
romance Hypnotic Romance
Missbehavin Neva posted a topic in Favorite DestinationsHypnotic Romance is a special place for Love & Romance with couples dances, secluded places to cuddle and kiss, and hidden throughout are special romantic animations. Bring your partner, lover or date or come alone to meet someone with romance on their mind & lots of places for photography. http://maps.secondlife.com/secondlife/Hypnotic Romance/128/128/22 Share your special moment photos on Flickr: https://flic.kr/g/AUXz1
Hibernation Termination
BbytheLake posted a topic in Make FriendsHello friends I haven't met yet, I've been in newbie hibernation for a year and a half. I've had the opportunity to explore, shop and get comfortable with things in this amazing world of SL. I still have a lot to learn and I look forward to doing just that. For now, I am looking for friends. Where are your favorite hangouts? I need place recommendations to peel me out of my hibernation. Thanks for suggestions!