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text:
International Space Station Expedition Six Crew Interviews with
Flight Engineer Donald Pettit.
Don, you're set to begin about a nearly four-month-long mission
in space. Tell me, what is the goal of this expedition to the International
Space Station?
A: The goal
of any mission to space station has several facets to it. Certainly,
one goal on this mission is to continue the construction of space
station, because it's still an entity that's very much under construction,
we're in the process of building it. So, we want to continue the
construction. We need to maintain the outpost and the human presence
there. We need to keep the crew working on station, we need to keep
them happy, supply them with materials they need in order to stay
there. They need to do repair and maintenance and keep the space
station working properly. And then, there's also the scientific
payloads and other observations that can be made from an orbiting
platform that we will be doing.
for your crewmates, launching from the planet is nothing new, but
for you, this is your first trip to space. Tell me what your reaction
was when you got word that you had been named to the prime crew
for Expedition Six.
'cause I had been training for backup for over a year-and-a-half.
You realize that something like this can happen, and I was surprised
when it did happen. I'm ready to go. The training programs here
are good, so there's no surprises in terms of the skills needed
and the tasks that are going to be asked of me to do.
has it been like for you to step in with Ken and Nikolai, and move
along with the training?
it's been smooth. I see Ken and Nikolai a lot in the course of our
training anyway. And, we're all professionals about this. And if
something comes out so a new face shows up, you just keep on working.
mentioned you've been involved with this mission for more than a
year, you've been training as a backup since early 2001. From your
point of view, is this a pretty good example of why it's a good
idea to train backup crews?
I think it
is an example of why you have backup crews. Any time you have a
mission where there's a long period of training and a lot invested
in the crew classically you have backups: We did this for Apollo,
the Russians have done this for their long-duration space missions.
It's a smart thing to do 'cause things can operate outside of your
control, and you may need to have a backup crew come in, and here
I am.
the circumstances, is it the fulfillment of a lifetime dream to
finally be, have those words told to you, you're going to fly?
I consider
myself an explorer. And you can explore in many different ways,
whether it's under the stage of a microscope or running off in a
laboratory and making other measurements. I've been an explorer
for as long as I can remember…exploring space is just one aspect
of that, it's something that I've been interested in since I was
a little kid, and now I'm doing it, or going to do it.
you remember why it is, in your own life, that maybe even as you
were a kid that you wanted to be an astronaut in the first place,
or, as you say, to be an explorer?
I think it
just comes from the fabric of who you are, the curiosity you have.
I've just always wanted to explore, whether it's looking at oil
drops on a mud puddle or, [an] anthill that you happen to be walking
by. All of this is exploration, and exploring space is just a part
of one of the many topics that you could work on as an explorer.
you, tell me about the path that you took to become an astronaut.
In terms of your education and your career, what did you do that
led you to become a person who was astronaut material?
I went to
undergraduate school at Oregon State University in chemical engineering,
and from there I went to University of Arizona to do my graduate
work … not with becoming an astronaut in mind, but because these
were fields that I wanted to study. And then it wasn't until I was
graduating from graduate school that I thought of putting an application
in to the program and applying to be an astronaut. And from graduate
school at University of Arizona I went to Los Alamos National Laboratory,
where I functioned as a staff scientist there. And eventually, I
got an invitation to come in for an interview for astronaut.
that a nerve-wracking experience? Or is it just so thrilling, that
you seem to be moving ahead in that pursuit?
It's nerve-wracking
and thrilling. It's more thrilling to be able to come in and do
an interview for astronaut; it can be nerve-wracking if interviews
and things like that tend to make you a little bit on the nervous
you look back over all of those things, can you point it to the
people who either were or maybe still are the most significant influences
in your life?
my parents were huge influences, and my brothers, and then college
professors, particularly some at Oregon State University and then
at University of Arizona, had a huge warping of who I am today.
Yeah … trying
to change you into somebody that can get to the crux of a complex
technical problem and come up with a solution.
been since 1996 since you've been an astronaut and been around the
Johnson Space Center, from a time when the Shuttle-Mir Program was already under way and, as we'd mentioned, you've been training for
this mission for more than a year now. From your point of view and
seeing what you've seen during that time, do you see that the nations
that are partners in the International Space Station program seem
to be succeeding in the goal of learning how to work with one another?
Learning to
work with one another, particularly in an international program,
is sort of like an onion in that you have all these layers, and
you peel another layer off and you think you're making good progress
and then you realize there's another layer yet for you to peel off.
And as I'm getting older, I'm finding a lot of things in life are
like an onion.
there are a lot of layers, then, in the relationships among the
There's a
lot of layers in terms of learning how to work with each other.
And it can always get, there's always ways that you can improve
how you are working, and you can look back, though, and see that
you've made a lot of progress because you've dug through a lot of
order to complete this mission, the members of the flight crew have
to possess a range of talents in order to do all the jobs. So, tell
me what are some of your main responsibilities as a member of Expedition
I'm going
to be doing a lot of the maintenance and repair on station during
this increment. I'm going to be the science officer, so I'm going
to be in charge of making sure all the scientific payloads get done.
And then, I'll be the main robotic arm operator.
robotics are going to play a big part in the first act of your mission,
if you will, when you and your crewmates are delivered to the station
by Jim Wetherbee and his crew. The first day of docked operations
of that shuttle mission includes the installation of the P1 truss
segment, which requires the use of robot arms. Tell me about what
happens that day, and point out, if you will, what your responsibilities
as part of that team are going to be.
OK. The P1
Truss robotic arms operation is going to be done by the current
crew that's up there, so I won't be partaking in that. I'll be doing
the robotic arms operations involving the EVAs after the truss has
been installed.
far as the P1 installation, though, can you describe for us what
is going to occur in order to complete that job?
You need to
latch onto the arm, latch onto the P1 Truss with the arm, and pull
it out of the payload bay and move it into position and latch it
onto the end of the S0 Truss. And basically, that's it in a nutshell.
this is an undertaking, if you will, that's going to involve that
unusual aspect of having two robot arms working at the same time.
That's true,
there's a handoff. You pull it out with the shuttle robotics arm
and you hand off to the station robotics arm, and then you put it
in place with that.
you're not scheduled to be doing either of those tasks, I'm sure
you've been around while they've practiced it. Is that as difficult
as it looks to those of us on the ground?
You certainly
have to concentrate on what you're doing. It's a pretty well-scripted
and pretty well-practiced operation.
day after the P1 installation is the day that you and Ken and Nikolai
are scheduled to officially move onto the station. What has to happen
in order for that exchange to be finalized?
You need to
transfer the lozhiment, the Soyuz couches, and you need to make
sure that your Sokol suit, the launch/entry suit you wear in the
Soyuz capsule, those two items have to be transferred. That's the
main criteria for crew handover. And this allows you to use the
Soyuz spacecraft as the emergency escape vehicle and come back down
to Earth.
special about the equipment that you're bringing that makes that
Well, the
Sokol suit is custom-fit to you, and chances are no one else is
going to be able to fit into it. And, same thing with the couch
-- the Soyuz spacecraft has a rather hard landing, and you have
a formfit couch that's fit to your back to keep you from getting
injured during that landing. And it would be ill advised to land
in a Soyuz capsule with someone else's couch.
the many days of docked operations on this shuttle mission, there's
time set out for an activity that's called handover, involving you
and your crewmates and the Expedition Five crewmates. What is it
that you folks do and talk about during this period, and how is
it going to help you guys get off to a running start, if you will?
Well, in crew
handover, they talk a lot about stowage, in terms of where things
are. And you can imagine going into somebody's garage, it's jam-packed
full of stuff, and saying, here you go, and then giving you a task
list where you have to find a hundred and fifty items and put 'em
together for an experiment; it's going to take you a while. And
so, much of the handover involves with going over where things are
stowed and how to find things. Another aspect of handover is learning
the little nuances of operating the equipment, which you don't learn
when you're on the ground. And sometimes you read about the design
of equipment, and they say the green light comes on before the red
light, but then the way it really operates the green light doesn't
come on at all, and only the red light comes on. And you don't know
these kinds of things until you get into orbit, and that's part
of what the handover is about.
shuttle crew, who is going to head home with your predecessors and
leave you three to settle in and get comfortable with your routine
on orbit, assuming there's such a thing as "routine" life
240 miles above the planet? Can you describe what, if there is one,
is a "normal" day in space?
Well, I can
answer this question better after I come back. In terms of how we
simulate routine days on orbit, I basically start off in the morning
with a cup of coffee and you look at the timeline that was uplinked
that tells you what you're going to be doing that day, and then
you have a short powwow with the ground to go over any questions
that you might have, and then you just roll up your sleeves and
start doing all the things they want you to do, which will be a
mix of maintenance items, maybe replacing filters or checking fluid
levels in tanks or something like that or setting up and doing payload
experiments, or getting things pre-positioned for the next day's
you work five days a week? Seven days a week?
I think you
work however many days a week you need to work. And, if you get
a day off then you relish that. But the folks on orbit, I think,
you're pretty much working all the time.
are a variety of categories of science to be done during your time
in space. One of them is called Human Life Sciences research. What
is the value of examining how people live as they do in low Earth
OK. When you
do research associated with exploration, you're in a unique environment
and you learn new things about people and new things about nature.
And these in themselves enrich the knowledge for everybody that
doesn't go on the exploration trip. One example I like about human
physiology in exploration is transoceanic exploration in the 14th
and 15th century and the role of diet and vitamin deficiencies.
And, it was this kind of exploration that helped open the can of
worms leading to things like vitamin C and its role in scurvy, and
this information was pried, so to speak, from the souls of the early
explorers. And once you learn this information, then it helps and
benefits everybody back on the continent that didn't get a chance
to go on these trips. And I see this as the goal of the life science
research on space station.
trying to find out how people live in that environment?
Well, there's
several facets. One, you need to find out changes in the body and
the physiology of the body in reduced gravity so that you can enable
future exploration missions of long duration, perhaps going to Mars
and elsewhere, so that's one facet. Another facet is learning nuances
about how your systems in your body work, and knowing that may help
improve the lives of people that are still on the planet.
me about a couple of the Human Life Sciences experiments that you'll
be working with during your mission.
Well, one
of them is kidney stone formation. It's fairly well known that you
decalcify your bones, your bones lose calcium, and this comes out
in your urine, and you have a greater propensity of making kidney
stones. And so one of the life sciences experiments involves collecting
a number of urine samples over the whole course of the mission and
looking at the calcium and trying to link that with diet.
one, are there other human life sciences experiments that, -
Oh, there's
lots of experiments in which we can be guinea pigs for, and I say
that in a positive sense 'cause perhaps one of the better data sets
that will come from space station is 10 or 15 years of the life
science data collected on human beings. We're doing muscle biopsy
experiments, where they go in and maybe not take a pound of flesh
but they take some flesh and they look at your cross section of
slow-twitch and fast-twitch muscle fibers. And then they see what
the effect of living for long periods of time in a reduced-gravity
environment does on, for that.
another category of experiments for your mission that's called microgravity
science. Now, while I think everything that you do is microgravity
science, since that's where you are, what's the distinction about
this subset of investigations?
The microgravity
science experiments are generally physical science experiments:
crystal growth, combustion, things like that. And, they are utilizing
an environment where there are small sedimentation forces, no buoyancy
forces or reduced buoyancy forces, things that will allow you to
do containerless processing, where you can have something floating
around without touching the walls of a container, or a high vacuum,
high pumping rate environment like an experiment done outside of
the pressurized modules on an exposure platform.
sort of things in general is it that we're trying to learn here
that could be of value to us on Earth?
Well, many
observations in science are key around the balance of forces, measuring
one force in the absence of another. And many of the phenomenon
that we see on Earth are governed by the balance of these forces.
So if you remove, say, gravitational force, now all of a sudden
you can see surface tension force. And so, experiments done on space
station are designed around the reduction in the gravitational force
so that you can see other forces manifest themselves and you can
make new observations that are very difficult, if not impossible,
to make any other way.
just the point exactly: that you have to do these in that environment,
you can't do them here, can't do them on the ground.
Exactly. Some
experiments you can come, you can, you could start some experiments
on the ground-for example, plant growth experiments where you hold
the plant horizontal to gravity and just rotate the base of the
pot; that, the first order can kind of null out the effects of gravity,
but, it's a different regime when you try to grow plants in long-duration
reduced gravity.
talked about a couple of these general areas of science research
that are to be done, and, these things have been under way since
the first of the Expedition crews arrived. In fact, you're going
to get to the station roughly two years after the arrival of the
Expedition One crew. Two years' worth of human habitation, continuous
human habitation, in this environment. In your opinion, Don, what
is it that you think is the best thing that's come out of this two
years of work on board ISS?
Well, most
of the two years has been devoted to building the space station
and learning how to run it, and I think everybody associated with
space station is a whole lot smarter now than they were two years
ago on, just, how do you get the crews up there, how do you keep
'em supplied with goods and materials, how you conduct experiments
between folks on orbit and folks on the ground, how you deal with
the international aspect of it where you have people scattered out
on the ground through nine time zones. Just learning how to live
and work together, both in orbit and on the ground, I think, is
one of the biggest lessons we've learned so far.
Curator: Kim
Dismukes | Responsible NASA Official: John Ira Petty | Updated: 01/10/2003Web Accessibility and Policy Notices

subset: commoncrawl


text:
Honeybees fall to predatory wasps
This summer has been an exercise in honeybee defense — defending my hive against mosquito fogging, against an infestation of earwigs, against the aftermath of a failing queen.
As recently as three weeks ago, things seemed to be on the upswing. Inside the hive, the new queen was laying eggs. The workers were brooding larvae. Honey cells were full and capped. There was plenty of pollen. I knew there would be no extra honey to share with me this fall, but my docile Italian girls seemed to have their collective act together well enough to survive the winter and try again next spring.


text:
UNIVERSITY PARK, Pa. -- A five-student team known as "Leafy," marketing a wireless sensor that detects moisture directly from plant leaves, won the $7,500 first-place prize April 10 in Ag Springboard 2014, a student business plan competition designed to spark and nurture innovation in agriculture.
The Entrepreneurship and Innovation Program in Penn State's College of Agricultural Sciences sponsors the Ag Springboard event, with the support of benefactors Earl and Kay Harbaugh, lead donors for the program.
Five finalist teams presented their business plans throughout the day's final round to a panel of entrepreneur judges familiar with the food, agriculture and biorenewable energy sectors.
The Leafy team's plant moisture sensors attach directly to plant leaves without damaging them and use technology that makes them more accurate than other devices that measure moisture from parts of plants, said Amin Afzal, graduate student in agronomy, who invented the device.
"It's a great win and an opening of new opportunities for me," said Afzal. "It's a turning point -- a switch from the academic to commercialization."
Farmers can use the sensors, which integrate with crop-management software, to optimize crop irrigation. Afzal studied agricultural machinery engineering at the Isfahan University of Technology in Isfahan, Iran. He has developed the plant sensor over the past decade and is in the process of patenting it.
For Ag Springboard, he worked with four master of business administration students -- Masoud Ghayoumi, Iqbal Asim, Marcus Cullen and Ankit Mahajan -- on finance, marketing and distribution plans to develop strategies toward commercialization.
Based on an analysis of acres of U.S. cropland in drought-affected areas, such as California's Central Valley, Leafy estimates potential sales of more than $1 billion.
Leafy's presentation was impressive, noted Mark Gagnon, Harbaugh Entrepreneurship Scholar and the college's entrepreneurship coordinator. "They took this technology that Amin has been working on for 10 years and developed and packaged it into an extremely compelling business case," he said.
Gagnon explained that this competition wasn't just an academic exercise. "This team has the makings of a profitable, viable business."
As he announced winners, College of Agricultural Sciences alumnus Earl Harbaugh, creator of five Illinois businesses including Ditch Witch Midwest, said the team presentations were outstanding, and judges struggled with a close call between first and second place. The runner-up team was Vine Roofs, which offers vegetative roofs at a lower cost than conventional green roofs.
The caliber of the teams and their presentations has increased significantly from prior Ag Springboard competitions, according to Gagnon. "We're starting to build a following of students who are growing active companies and ventures from Ag Springboard," he said. "Students are building on the momentum and creating companies and nonprofits."
Previous winners of Ag Springboard spoke during the evening's festivities, including members of Green Towers, which is working to create consumer-friendly hydroponics products. In addition, Fengchun Yang described his experience learning and exploring business opportunities with the larvae of black soldier flies.
Anne Yorks, CEO of Flour Box Bakery in Zion, described the creation and success of her custom cookie-decorating business -- without taking on debt.
"We started slow and small and used any opportunity to re-invest in the business," said Yorks, who related how she and her husband worked with friends and family over time to convert her two-car garage into a bakery, doing a lot of the work themselves to save money.
"We were surprised at how much we were capable of doing," she said.


text:
webmatic necesitaba un nuevo diseño de logotipo y lanzó un concurso de diseño en 99designs.
Un ganador ha sido elegido entre 759 diseños de 151 diseñadores freelance.
The CityRentals team consist of a relaxed and fun group with the same goals, drives and ambitions. Having been involved in the marketing and web development sector for some time and being involved in many web projects we see value in a project such as the CityRentals project.
CityRentals is a project which aims to put apartment and house owners offering a furnished place to rent together with someone looking for a place to stay. Our target audience is both the vacation renter looking to rent fully furnished apartments offering Internet service, cable TV, telephone and all the amenities that you'd have as though you were in your own home. The second being the corporate renter looking for short term furnished rentals. The main difference between the two will be that one (the vacation renter) will typically be looking for a few weeks to a maximum of a monthly stay whereas the corporate renter will be generally looking for slightly longer stays (a few months at a time). Initially we're also going to be focusing on people that are looking for vacations or corporate rentals in big cities.
We're really looking for a logo to represent our brand that will consist of type as well as a iconic symbol to help represent the brand both initially and as it matures.
What we're looking for is to have an icon that is separate from the text so that the text can be used independently of the icon and visa versa. The icon should look good both in really small dimensions as well as larger proportions thus it should be relatively simple so it can scale well. It should look good in black and white as well as in a color version. The main idea we have it so try to incorporate a "key" into the icon portion of the logo. Alternatively concepts that stand out as resembling something that a company catering to offering listings of city rentals and connecting renters with apartment and home owners will be looked at fondly.
Things to consider:
1. The logo should look good in both portrait and landscaped mode & be adjustable by allowing us to move the iconic component of the logo
2. Use colors that instill confidence and allow the logo to show very clear and vibrantly on a white or light gray background.
3. An icon that's associated with the logo that scales well from small to large will be the most ideal for us as well as we'd like to use the logo on the site, print, ads, etc...
4. Text in logo should be lower case.
Descubre cómo funciona un concurso de diseño u obtén más información sobre nuestros servicios de diseño de logo.


text:
PhotoGraphics Image Collection (PIC)
What is the PhotoGraphics Image Collection (PIC)?
The PhotoGraphics Image Collection (PIC) is your photographic imaging resource. We maintain a collection of images available for use in your university publications, presentations, displays, and websites. The database features images of UMass Dartmouth events, architecture and campus life, as well as faculty, staff, administrators, alumni and students in a wide variety of settings.
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Download the PIC Tutorial for help with navigating PIC and taking advantage of its features.
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text:
ACUSON X300 Ultrasound System, Premium Edition
Performance meets accessibility.
The ACUSON X300™ ultrasound system, premium edition (PE) is a compact, portable imaging solution that delivers exceptional clinical performance across a wide variety of applications. This comprehensive, fully featured system incorporates high-end image optimization techniques and enhanced workflow features to meet the challenges of the most demanding care environments.


text:
The block busting games genre is updated with power-ups and interactive 3D backgrounds, which you build while exploding chains of same coloured blocks.
1 Players
See it in action
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text:
Doors: 6:00 PM
Show: 7:30 PM
21 and over
For this and many of the events hosted here at The RCC, our members receive special ticket access and discounts. If you're interested in learning more, Click Here.
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Event has ended.


text:
Al Gore
|Al Gore
|45th Vice-President of the United States
|Term of office
January 20, 1993 - January 20, 2001
|Political party
|Bill Clinton
|Preceded by
|Dan Quayle
|Succeeded by
|Dick Cheney
| March 31, 1948
Washington, D.C.
|Tipper Gore
Albert Arnold "Al" Gore, Jr. ( born March 31, 1948) was the 45th Vice President of the United States (1993-2001), succeeding Dan Quayle and succeeded by Dick Cheney, following service in the House of Representatives and the Senate, spanning 1977-85 and 1985-93, respectively. He is a Nobel-prize winner for his work on global warming; Gore spreads alarmist propaganda, proclaiming the end of the world. Gore likes to say that, "The Earth has a fever," [1] and is making millions of dollars through his fraud scheme.[2] He has no degree in atmospheric sciences, meteorology, physics, chemistry, biology, or climatology. Gore took two science classes as an undergraduate, scoring a "C+" in one and a "D" in the other. [3] Among his notable achievements, the one he is least known for is casting the tie-breaking vote to tax elderly Social Security benefits who earn as little as $22,000 per year.
Gore was the Democratic Party's candidate for President in the 2000 election, running on a ticket with Sen. Joseph Lieberman of Connecticut.
In his early life, Gore attended Harvard University and (briefly) Vanderbilt University. He also served in the United States Army and worked as a war correspondent during the Vietnam War.[4] He is married to activist Tipper Gore, but the two announced on 6/1/2010 that they were separating after forty years of marriage. [5]
Gore is currently the chairman of liberal television network Current TV.
Sexual Assault Accusations & Investigation
Not long after the split became public, Portland, Oregon police announced that they had investigated Gore on sexual assault charges over an encounter with massage therapist Molly Hagerty in October 2006. [6]
Hagerty, a massage therapist to the stars, has accused the former vice president of repeatedly groping and kissing her during a late-night, alcohol-fueled attack in a Oregon luxury hotel suite in October 2006. Detectives investigated the claims in 2006 and 2009 but decided not to pursue the case. However Portland Police Chief Michael Reese said on July 1, 2010, that "we have determined there were procedural issues with the 2009 investigation that merit reopening the case." Officers took the accuser's statement but didn't proceed further and didn't clear that decision with higher-ups. In addition, prosecutors were not made aware of the 2009 investigation until recently." [7]
Political Career
Al Gore followed his father, Albert Gore, Sr. a prominent Democratic Senator from Tennessee, into Congress. His father was a supporter of the New Deal who was finally defeated in 1970, despite having sent his son to Vietnam in order to bolster his campaign.[8]
Al Gore was initially somewhat conservative on social issues, supporting Clarence Thomas for the Supreme Court and, along with his wife, opposing offensive lyrics in rock music. But as his presidential aspirations grew, Gore became increasingly liberal.
Gore ran for president in 1988 but was defeated in the primary by Michael Dukakis. Gore then continued to serve in the Senate.[9]
In the 1992 Presidential Election, Democratic nominee Bill Clinton selected Gore as his running mate. They won the election, and Gore was sworn in as Vice President on January 20, 1993. Clinton and Gore were elected to a second term in 1996. Gore had little influence in the Clinton Administration, and almost nothing of significance is attributed to him.
As is often the case for incumbent Vice Presidents, Gore was nominated as his party's candidate in the 2000 Presidential Election. He lost to George W. Bush in the Electoral College after a close vote, in which Gore received more popular votes than Bush, but fewer electoral votes. Gore contested the results in Florida. On December 13, 2000, after an extensive court battle (Bush v. Gore), Gore accepted Bush's election to the presidency.[10]
Cast tie breaking vote to increase taxes on Social Security
In 1993 President Clinton sought to increase taxes on Social Security benefits of the elderly and disabled.[11] The final version of the bill passed by the Democratically controlled Congress increased taxes on beneficiaries from the first 50% to 85%[12] of benefits (or "annuity payments" as they were originally called). Vice President Al Gore cast the deciding tie-breaker vote in the Senate to make the tax increase law. The Clinton-Gore tax increase on Social Security benefits imposed a 70% income tax rate on a retired couple making as little as $22,000 per year.[13]
Al Gore and uncharitableness
See also: Liberal politicians and uncharitableness and Barack Obama and uncharitableness
The political magazine the American Spectator declared:
|The last two Democratic Party nominees for President have come up short on the charity scale. Al Gore has been famously stingy when it comes to actually giving his own money to charities. In 1998 he was embarrassed when his tax returns revealed that he gave just $353 to charity...[14]
In 1988 Gore courted the support of controversial activist Fred Phelps of the Westboro Baptist Church in Topeka, Kansas. In appreciation for Phelps' help and support of Gore, Phelps was provided tickets to the inauguration of President Clinton in 1992 and 1996.[15] Phelps has since changed his opinion about Gore when he joined Bill Clinton on the 1992 presidential ticket. Phelps turned on him and claimed Gore was a conservative icon of the Democratic Party that sold out on some critical social issues. Phelps also demonstrated against Clinton and Gore during the 1997 inaugural. [16] [17]
Current activities
Gore has started an investment firm to invest in environmentally sustainable technology and industries and a cable channel (Current TV), and is an adviser to Google. He was also mentioned as a possible 2008 presidential candidate.
Gore and the Intergovernmental Panel on Climate Change shared the 2007 Nobel Peace Prize for his work on climate change.[18]
Gore is the author of The Assault on Reason. He also starred in the 2006 film about global warming entitled, An Inconvenient Truth, which won an Academy Award. In 2007, the British High Court directed teachers to inform students to whom they show the film that it "is a political work and promotes only one side of the argument" and to draw attention to eleven specific inaccuracies. Furthermore, the court advised, "If teachers present the Film without making this plain they may be in breach of ... the Education Act 1996 and guilty of political indoctrination."[19] Despite the errors, the judge also concluded "four main scientific hypotheses, each of which is very well supported by research published in respected, peer-reviewed journals and accords with the latest conclusions of the IPCC." [20]
Speaking in Manhattan to the fourth annual Clinton Global Initiative, Gore wants to use "civil disobedience" to combat the construction of coal power plants without the ability to capture carbon. [21] Civil disobedience or the call for intentional violation of laws is an extremist point of view. It is believed that he was speaking in regards to Western nation coal plants. No mention of China and their coal production. The gravest threat from coal pollution comes from China, in which two plants are constructed per week and 500 more plants over the next 10 years. [22]
- Gore said, "I took the initiative in creating the Internet." [23]
- Gore falsely claimed that he discovered problems in Love Canal and fixed them. He said:
- "I called for a congressional investigation and a hearing. I looked around the country for other sites like that. I found a little place in upstate New York called Love Canal. Had the first hearing on that issue."[24]
- "That was the one that started it all. ... We made a huge difference and it was all because one high school student got involved."
- "I love Van Jones. I love his work. I love his heart and his commitment and his intellect. I love his mission. He has wisely picked a part of this set of interwoven challenges that should have been addressed much more forcefully by me and others long ago."[25]
- During an interview with Slate, regarding the Climate Research Unit at East Anglia University, a question was asked concerning a sense from the Climategate e-mails and from data that was "hidden and hoarded." These truths are the opposite of the case Al Gore made in his book about having an open and fair debate. Gore responded with a lack of command of the most basic details of anything related to Earth and climate. He said,
|I haven't read all the e-mails, but the most recent one is more than 10 years old. [...] So an e-mail exchange more than 10 years ago including somebody's opinion that a particular study isn't any good is one thing [...] but where the scientific consensus is concerned, it's completely unchanged. What we're seeing is a set of changes worldwide that just make this discussion over 10-year-old e-mails kind of silly.[26][27]
- The most recent emails in Climategate were from November 12, 2009.
- In an interview aired on the CBS Early Show, Al Gore read his global warming poem to Harry Smith.[28][29]
Ann Coulter claims Gore exaggerated his military service record: "Al Gore endlessly bragged to the media about his service in Vietnam. 'I took my turn regularly on the perimeter in these little firebases out in the boonies. Something would move, we'd fire first and ask questions later,' he told Vanity Fair. And then we found out Gore had a personal bodyguard in Vietnam, the most dangerous weapon he carried was a typewriter, and he left after three months."[30]
In 2007, Al Gore received criticism for his high electricity use. When it was discovered that Gore's electric utility bill is 20 times higher than the average American's[31] many of his detractors accused him of not living up to his own standards. In the year since the 2007 criticism, energy use at Gore's mansion increased 10%.[32] Gore's defenders claim that the majority of that power came from "green", or environmentally friendly, power sources such as solar and wind power. These power sources are much more expensive than traditional power sources such as coal and nuclear power.
Also, some conservatives have pointed to Gore's use of a private jet while spreading the message about the dangers of global warming.[33]
Attention has also been called to Gore's profits from mining royalties, specifically the mining of zinc adjacent to his property that he leased in Tennessee, which has released millions of pounds of potentially toxic substances into the environment.[34] The mine has been closed since 2003. New owner Strategic Resource Acquisition is planning to re-open the mine. From The Tennessean (3/12/07):
"Last week, Gore sent a letter asking the company to work with Earthworks, a national environmental group, to make sure the operation doesn't damage the environment.
'We would like for you to engage with us in a process to ensure that the mine becomes a global example of environmental best practices,' Gore wrote."
However, this was after he had already made $500,000 from the mining operations.[35]
Al Gore's fondness for using buzzwords became the focus of a prank played on Gore by students at Massachusetts Institute of Technology in 1996. MIT students distributed a bingo card containing meaningless buzzwords Gore was known for peppering his speeches with, including "infobahn", "knowledge worker", "vector", "high confidence", and "information marketplace". Sure enough, during Gore's speech at MIT, a commotion erupted in the audience when enough buzzwords were said to complete the Bingo card.[36]. Gore's current favorite buzzword is "unified national smart grid", which he promotes in conjunction with his catastrophic global warming prophecies, earning him ridicule as "The Goracle" in a Washington Post article by Dana Milbank.[37] Bjorn Lomborg has additionally criticized Al Gore for framing global warming using buzzword terms as some sort of transcendent generational quest, as when Gore called the so-called "climate crisis" the "chance to experience...a generational mission, the exhileration of a compelling moral purpose, a shared and unifying cause, the thrill of...the restless human need for transcendence."[38]
Fabrications and blunders
- On February 20, 2000, Gore claimed he has "always, always, always" supported Roe v. Wade. However, in 1977, he voted for the Hyde Amendment, which says that abortion "takes the life of an unborn child who is a living human being," and that there is no constitutional right to abortion. He cast many other votes favorable to the pro-life cause and earned an 84 percent rating over the course of his entire U.S. House career (1977 to 1984) from the National Right to Life Committee.[39]
- On February 4, 2000, Gore claimed, "We had a huge event with 3,000 people at Ohio State University." In reality, "Officials at that rally said the room where it had taken place did not hold more than 1,200 people, and, given the area needed for the staging erected for the occasion, they estimated the crowd at 500," according to known liberal media source the New York Times.
- On February 2, 2000, on Good Morning America Al Gore claimed, "We won in every single demographic category" in the New Hampshire primary. In reality Bill Bradley carried male voters and voters aged 18-29, according to exit polls.
Gore's comment that he "took the initiative in creating the Internet" was criticized in the St. Petersburg Times (Florida):
- This was not the first time Gore has overreached. A year ago Gore told reporters that he and his wife, Tipper, at the time when they were college sweethearts, were the inspiration for the novel "Love Story." That came as news to the befuddled author, Erich Segal. [3]
Gore wrote an opinion piece in the New York Times in which he said "[he] genuinely wishes global warming was an illusion," claiming it is very real. This despite mountains of fraud uncovered by ClimateGate. Fred Thompson replied, "Hey, Al... the genie says you still have two wishes left." [40]
See also
External links
- Official website
- Al Gore, Ignoble Laureate, Investor's Business Daily, October 5, 2007
- Al Gore News and Commentary from the New York Times
- What Liberals Say - Al Gore, Accuracy In Media
- Yearly Frozen Gore Ice Sculpture In Alaska
- ↑ http://abcnews.go.com/GMA/GlobalWarming/story?id=2110628&page=1
- ↑ http://newsbusters.org/node/11149
- ↑ http://www.larryelder.com/Gore/goredubiousrecord.htm
- ↑ Kennedy,William V. The Military and the Media: Why the Press Cannot Be Trusted to Cover a War. Westport: Praeger Publishers, 1993. <http://com.hilbert.edu/students/papers/carolina-1999/1999vietnam.html>
- ↑ Gore's Break Up After 40 Years of Marriage
- ↑ http://www.google.com/hostednews/ap/article/ALeqM5jdRlS1EbF66_3PpAvC9UlCbBtuqgD9GIKE580 AP; Police release tape from Al Gore sexual assault accuser's interview
- ↑ Portland police mishandled Al Gore sex-abuse case, Chief says.
- ↑ http://www.cnn.com/SPECIALS/2000/democracy/gore/stories/gore/
- ↑ While serving in the Senate, Gore introduced the High-Performance Computing Act of 1991, signed December 9, 1991, which his supporters claim helped develop the Internet and the National Research and Education Network. [1] [2] When Gore himself bragged about creating the internet, he was referring to prior legislation (see quotations below).
- ↑ Leip, David. "2000 Presidential General Election Results." David Leip's Atlas of U.S. Presidential Elections. 2005. 18 Mar. 2007 <http://uselectionatlas.org/RESULTS/national.php?year=2000>.
- ↑ http://www.house.gov/house/Contract/seniorsd.txt
- ↑ http://web.archive.org/web/20040408115747/www.ssa.gov/OACT/HOP/hopi.htm
- ↑ Congressional Record, Comments by Rep. Christopher Cox, July 27, 2000.
- ↑ http://www.liveleak.com/view?i=1c5_1238044126&c=1
- ↑ Gore sought help from anti-homosexual group, 'God hates fags' creator preaches 'hate because the Bible preaches hate', By Jon E. Dougherty, WorldNetDaily.com, October 25, 2000.
- ↑ http://www.frontpagemag.com/Articles/Read.aspx?GUID={91058469-F6DE-4615-8B2A-73CDF3E8FCAC}
- ↑ http://findarticles.com/p/articles/mi_qn4179/is_20001104/ai_n11753681
- ↑ http://www.foxnews.com/story/0,2933,312024,00.html
- ↑ Sheppard, Noel. "Court Identifies Eleven Inaccuracies in Al Gore's 'An Inconvenient Truth'." [Weblog NewsBusters] 08 Oct 2007. Newsbusters. 9 Oct 2007 <http://newsbusters.org/blogs/noel-sheppard/2007/10/09/court-identifies -eleven-inaccuracies-al-gore-s-inconvenient-truth>.
- ↑ http://www.foxnews.com/story/0,2933,301067,00.html
- ↑ Al Gore Urges 'Civil Disobedience' Toward Coal Plants Fox News, September 24, 2008
- ↑ China's Coal-Fueled Boom Has Costs NPR, May 2, 2007
- ↑ Blitzer, Wolf. Transcript: Vice President Gore on CNN's 'Late Edition'. CNN. 9 March 1999. 2 June 2007 <http://www.cnn.com/ALLPOLITICS/stories/1999/03/09/president.2000 /transcript.gore/>
- ↑ http://www.cbsnews.com/stories/1999/12/02/politics/main72638.shtml
- ↑ http://www.newyorker.com/reporting/2009/01/12/090112fa_fact_kolbert?currentPage=all
- ↑ http://wattsupwiththat.com/2009/12/08/al-gore-cant-tell-time-thinks-most-recent-climategate-email-is-more-than-10-years-old/
- ↑ http://www.slate.com/id/2237789/
- ↑ Noel Sheppard. Gore Reads Poem, Harry Smith Swoons: 'Wow...I'm Happy to Hear it in Your Voice', NewsBusters, December 15, 2009.
- ↑ Rush Limbaugh. Algore's Idiotic Poem and All the Latest from the ClimateGate Stack, RushLimbaugh.com, December 7, 2009.
- ↑ http://www.anncoulter.com/cgi-local/welcome.cgi
- ↑ Al Gore - Electric consumption bill
- ↑ http://www.cnsnews.com/ViewCulture.asp?Page=/Culture/archive/200806/CUL20080619a.html
- ↑ More Inconvenient Truths About Al Gore
- ↑ Tennessee Mine Enriched Gore, Scarred Land
- ↑ http://archive.newsmax.com/archives/ic/2007/3/17/93301.shtml?s=ic
- ↑ http://hacks.mit.edu/by_year/1996/gore/
- ↑ http://www.washingtonpost.com/wp-dyn/content/article/2009/01/28/AR2009012803318_pf.html
- ↑ Lomborg, Bjorn. Cool It. New York: Vintage Books, 2008.
- ↑ http://www.gargaro.com/lifequotes.html
- ↑ [http://twitter.com/fredthompson/status/9876626632 Fred Thompson, Twitter feed, March 2, 2010


text:
Northern California Retina-Vitreous Associates (NCRVA) is one of the premier vitreoretinal practices. It was established in 1983 and has become the largest retina group in the Bay Area. We are dedicated to providing state-of-the-art care to our patients with diseases of the retina, macula, and vitreous.
All of our physicians are board-certified ophthalmologists with advanced training in vitreoretinal surgery. In addition to providing high quality care for our patients, we strive to advance our field through conducting clinical research and being active members of the teaching faculty at the University of California - San Francisco (UCSF) and Stanford University.
Many of our patients are referred by other eye doctors on an urgent and emergent basis for vision threatening conditions. We understand that each individual is unique, and we strive to provide personalized, compassionate, and attentive care. We are always available for you including after hours and weekends.


text:
Freeman looking at Monday return to Braves
PITTSBURGH -- As long as Freddie Freeman exits his final Minor League rehab game on Sunday without any problems, he will be activated in time to move back into the cleanup spot for the Braves in Monday night's series opener against the Rockies at Coors Field.
With Freeman back in the middle of the lineup, the Braves are planning to use Chris Johnson as their primary third baseman. Manager Fredi Gonzalez indicated on Saturday that was going to abort his plan to platoon Johnson and Juan Francisco at third base. He took a more committed stance on Sunday.
"He'll play third," Gonzalez said of Johnson. "The guy is leading the league in hitting."
Johnson entered Sunday leading the Majors with a .418 batting average. He has teamed with Evan Gattis and Justin Upton to serve as the most consistent contributors of a potent Atlanta lineup that has not yet lived up to its potential.
Entering Sunday, Johnson, Gattis and Upton had accounted for 40.4 percent (55 of 136) of the Braves' hits, 55.2 percent of the team's home runs (16 of 29) and 44.4 percent of the club's RBIs (32 of 72).
Despite playing in just five games before being put on the disabled list with a strained right oblique, Freeman entered Sunday tied with Francisco for the team's third-best RBI total, with seven.


text:
Perinatal asphyxia is a condition in which a baby's brain does not receive enough oxygen before, during, or after birth. This results in cardiorespiratory or brain damage.
Asphyxia can be fatal. Brain cells can begin dying within as little as 5 minutes without oxygen. It can also cause permanent, long-term damage, including intellectual disability, delayed development, seizure disorder, and cerebral palsy.
Perinatal asphyxia can be caused by a number of conditions that stop or slow the normal blood and oxygen flow to the baby's brain before or during labor and delivery. Some factors that may cause these problems include:
- Drop in the mother's blood pressure, which can decrease flow to the baby
- Pressure on the umbilical cord—interrupts flow of oxygen-rich blood to the baby
- Problems with the placenta, such as placental abruption when placenta moves away from the wall of the uterus
Risk Factors
Factors that may increase your baby's chance of perinatal asphyxia include:
- Fetal heart rate abnormalities
- Water breaking more than 12 hours before delivery
- Meconium (infant bowel contents) in the fluid surrounding the baby before birth
- Hemorrhage occurring prior to childbirth
- Infection in the mother that may cause breathing problems, such as pneumonia
- Prolonged first and second stages of labor
- Pre- or post-term labor
- Delivery with forceps or a vacuum device
Mild asphyxia may cause:
- Poor muscle tone
- Irritability
- Extreme drowsiness
- Feeding difficulties, including poor suck
Severe asphyxia may cause:
- Seizures
- Poor arousal
- Blue-colored skin or lips
- Difficulty breathing
A physical exam will be done. Typically, the history is the most important factor in making the diagnosis.
Your baby's body fluids may be tested. This can be done with blood tests, urine tests, stool tests, and tests of the fluid around the brain and spine.
Images may need to be taken of your baby's body structures. This can be done with:
- MRI scan
- Ultrasound
- CT scan
- Echocardiogram
Your baby's heart and brain activity may also be tested. This can be done with:
- Electroencephalogram (EEG)
- Evoked potential test for hearing and, rarely, vision
Life-sustaining Treatment
Life-sustaining treatment may be used if reduced brain function has happened, but there is no extensive damage yet. Treatment options include mechanical ventilation to take over or support breathing and oxygen therapy. These treatments will be stopped as your baby recovers.
Medication may be needed to support heart function until your baby recovers. Medication and general anesthesia may also be given to control seizures.
Lowering Body Temperature
Your baby may be wrapped in cooling blankets within hours of birth. This will lower body temperature and reduce the risk of tissue injury and reduce the risk of long-term problems.
Revision Information
- Reviewer: EBSCO Medical Review Board Alan Drabkin, MD
- Review Date: 03/2018 -
- Update Date: 04/04/2016 -


text:
Hammer Down Biker Fill In Invitations, 16ct
There is no better way to decorate a plain water bottle than with our Hammer Down Biker bottle labels!
Why serve plain water bottles to your guests when you can coordinate with the rest of your theme while adding a special flair and refreshing treat to your party.
Instructions for applying your water bottle labels:


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Dental Crown Cost
Dental crowns can be a great option for patients with decayed, broken, or missing teeth. Although most insurance companies may cover or partially cover the cost of your restorative treatment, the final dental crown cost will be dependent on a number of factors including the extent of your damage, whether your crown is manufactured onsite or in a lab, and your desired results. During your consultation, your doctor will assess your condition and recommend a treatment plan that best helps you restore long-lasting health to your smile. The starting cost for a dental crown can range anywhere from $500 to $2,500.


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Disaster recovery report card: Measuring your company's disaster recovery profile
Disaster recovery planning is challenging because you don't know what you're planning for or how well your disaster recovery plan will hold up in the face of an emergency. Use this report card to measure your disaster recovery plan and identify areas that need improvement.
Disaster recovery preparation is challenging because you don't know exactly what you're preparing for. Events like Hurricane Katrina also point to our inability to reliably predict the scale of damage and the inability of government at all levels to cope with the aftermath of an adverse event. The adverse event can range from extreme weather conditions or disturbances in the earth's geology to human-related events caused by errors, accidents or malice.
Regardless of the cause, adverse events become disasters when the event's negative consequences affect your company's ability to maintain operations. Even though IT planners cannot predict what event may threaten the continuity of IT operations, the basics of disaster recovery planning and recovery requirements change very little. To see how your company's disaster recovery efforts may measure up, consider using the following criteria to measure your disaster recovery plan and the probability that your IT operations can be recovered to support your business operations within a short period of time.
Grade F (Unprepared)
Grade D (Marginally Prepared)
Grade C (Prepared)
Grade B (Well Prepared)
Grade A (All Set)
The days of having your entire backup and recovery tapes and hardware in the same building should long be a thing of the past for any of today's publicly traded companies reliant on their data systems. The technology and communications options available allow placing replicas in geographically dispersed locations and communicating backup data in near real time. Should an organization not want to invest in the resources themselves, pooling with others or using third-party providers should be considered as alternatives. Management should know the company's disaster recovery profile and have an honest assessment of the time it would take to recover after an adverse event. The grading scale above should provide a starting point and help communicate the situation in easily understood terms to decision makers regarding the ability to recover. It should also help to demonstrate the funding and resources needed to prevent an event from becoming a disaster by moving up one or more grades.
About the author
Dennis C. Brewer is the author of Security Controls for Sarbanes-Oxley Section 404 IT Compliance: Authorization, Authentication and Access published by Wiley. His resume includes a BSBA degree from Michigan Technological University, Novell Network Engineer Certification, and over a dozen years as an information technology specialist with the State of Michigan. He retired from his position as an IT security solutions specialist in January of 2006 from the State of Michigan, Department of Information Technology, Office of Enterprise Security and is now operating his own IT consulting practice in Laurium, Michigan.


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November 13 2015
Azure Multi-Factor Authentication Server as a RADIUS server
I use a maximum of one Google Ad per post to help offset some of my blog hosting costs.
This week I had a need to set up a RADIUS server in my lab. I decided to use an on-premise version of Azure Multi-Factor Authentication Server. It literally took just 5 minutes to set up and I was then receiving One-Time-Passwords via SMS for a measly sum of $0.17 (AU) per authentication. This is a very simple, flexible and impressive solution. More info and step-by-step instructions here:
- https://azure.microsoft.com/en-us/services/multi-factor-authentication/
- http://blogs.technet.com/b/ad/archive/2013/10/10/getting-started-with-windows-azure-multifactor-authentication.aspx
I use a maximum of one Google Ad per post to help offset some of my blog hosting costs.


text:
3D Printer parts 4pcs/lot DuPont line White Terminal Motor Connector cables XH2.54 4pin to XH2.0 6pin for Stepper Motor
length:1M / 2M
weight: 11g 22g
length:1M 1PCS OR 2M 1PCS
Using no feedback
1. All products will be tested with power on before delivery, to ensure all the functions are ok.
2. After receiving the product, please do the test as soon as possible. Please read the manual carefully before testing or using the board. ) Please pay special attention to avoid the circuit burned and static electricity breakdown caused by improper connection. Please note improper operating and man-made damage do not belong to the warranty range.)
3. If you test the board and find it not work normally, please double check whether it's the problem of connections or software configuration (usually caused by these kinds of problems). After the double checking and the board still cannot work, please send the products back for us to check. The buyer pay for the return shipping cost first. If it's really the problem of the boards, we'll pay the shipping cost for both sides. But if after checking, we find the product is ok, or it's caused by improper operating/man-made damage, the buyers should bear the fees for the shipping and the replacements of the components. We are responsible for providing free maintenance services.
4. Free maintenance is available for 6 months from the date of purchase. Buyers are responsible for shipping cost and replacement parts. And we bear the shipping cost sending to the buyers.
5. Over 6 months, we provide paid maintenance services. The maintenance fees will be charged according to the specific situations.


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The Applied Water Management Group of American Water announced the initiation of New Jersey's first residential application of Reclaimed Water for Beneficial Reuse. The system activation ceremony will take place at Homestead of Mansfield, an Active Adult Community in Mansfield, N.J., on Friday, August 25 at 10:00 a.m.
A community of adults 55 and older, Homestead at Mansfield contains 1,200 residences. Located on a 295-acre site, the community is surrounded by sprawling grounds. "The Reclaimed Water for Beneficial Reuse project will provide reclaimed water to the lawns and common areas of the Homestead community, thereby preserving a portion of New Jersey's valuable water supply," said Mark Strauss, president of the Applied Water Management Group.
American Water's Applied Water Management Group acquired the community's existing wastewater facility in 1999, and for the next six years conducted a series of upgrades developed in conjunction with the New Jersey Department of Environmental Protection and aided by a grant from the New Jersey 1981 Water Supply State Bond Fund. The upgrades made to the wastewater treatment system will enable the delivery of high-quality water that will be used to maintain the residential grounds of Homestead at Mansfield and help achieve multiple state goals related to Smart Growth.
The August 25 event will officially engage the reuse system, with anticipated attendance by Homeowner Association Representatives, local and state politicians and representatives from American Water's Applied Water Management Group. "We are proud to be ushering in a new age of water conservation," Strauss said.
While this is the first residential application of reclaimed water in New Jersey, it's not the first reuse system developed and initiated by American Water's Applied Water Management Group. The Hugh L. Carey Battery Park City Authority (BPCA) tapped American Water to develop the wastewater treatment system in the Solaire, America's first "green," high-rise apartment building, which began operation in January 2004. Featuring 293 units, the building is the first of its kind to receive a LEED Gold Certification from the U.S. Green Building Council.
One of the Solaire's most significant green components is a wastewater system installed in the building's basement, which recycles and treats the building's sewage for reuse, such as toilet flushing, HVAC cooling and subsurface irrigation of an adjacent park. The wastewater system is also intended to supply reclaimed water to an adjacent apartment building, and for use, with further treatment, for subsurface irrigation in adjacent Teardrop Park.
The Applied Water Management Group has also introduced water reclamation plants to golf courses as a solution to meet the significant demands for water to maintain the grounds. One example is the system at the Hawk Pointe Golf Club in Washington, N.J. The reclaimed water is expected to serve as the primary source for maintaining the common grounds of the course, as well as the nearly 200 residential homes.
"Reclaimed water has been treated to a high quality and has long-term implications on water supply," said Edmund DeVeaux, vice president of business development for Applied Water Management. "Treating and reusing water that would otherwise be wasted helps conserve one of the earth's most precious natural resources."
The Applied Water Management Group of American Water announced the initiation of New Jersey's first residential application of Reclaimed Water for Beneficial Reuse. The system activation ceremony will take place at Homestead of Mansfield, an Active Adult Community in Mansfield, N.J., on Friday, August 25 at 10:00 a.m.


text:
Disclaimer: These software products are provided by DKIT AS AS IS.
DKIT AS makes no representations or warranties of any kind concerning the safety,
suitability, lack of viruses, bugs, inaccuracies, typographical errors or other
harmful components of these SOFTWARE PRODUCTS.
DKIT AS is not responsible for any service charges that may incur by the use of
SMS or network traffic generated by using or downloading these applications. Check your
network operator payment plan if this is an issue for you.
There are inherent dangers in the use of any software, and you are solely responsible
for determining whether any of these SOFTWARE PRODUCTS are compatible with your
equipment and other
software or hardware installed on or used in conjunction with your equipment.
DKIT AS will not be liable for any damages you may suffer in connection with using,
downloading or distributing these SOFTWARE PRODUCTS.
Questions? Comments? Contact the developer


text:
Get DVD Talk Feeds
Silly, gag-filled Lewis/Tashlin effort. Olive Films, having a lot of fun releasing all those great Paramount library titles, has another beloved Jerry Lewis title out, Who's Minding the Store?, the 1963 release co-starring Jill St. John, Agnes Moorehead, Ray Walston, John McGiver, Francesca Bellini, and a host of familiar, funny supporting players. A particular favorite with kids because of director Frank Tashlin's big, noisy, cartoony set pieces and gags, Who's Minding the Store? may not be fertile ground exactly for Tashlin lovers looking for his signature mise-en-scene―something he'd laugh at and dismiss, anyway―but who cares? It consistently delivers big belly laughs, and that's enough for Lewis' legion of fans (myself included). No extras for this so-so transfer.
Professional dog walker Norman Phiffier (Jerry Lewis) is in love with Barbara Tuttle (Jill St. John), an elevator operator at the massive Tuttle Department Store. What earnest, dopey Norman doesn't know is that Barbara has a secret: she's the heir to the Tuttle Department Store dynasty (26 operations all over the country). She doesn't want to tell traditional-minded Norman this because she knows he's proud (he wants to wait on their marriage until he's saved up the $800 dollars needed for the down payment on their Queens tract house), and because she's the first person Norman has ever felt he completely trusted. Barbara's controlling mother, Phoebe Tuttle (Agnes Moorehead), however, sees nothing good coming from her estranged daughter's marriage to a poor dolt, so she arranges to have Norman hired into the department store, where General Manager Mr. Quimby (Ray Walston) is to give Norman every dirty, impossible job imaginable, in the hopes that Norman will quit and disillusion Barbara right out of the engagement. Spineless jellyfish John P. Tuttle, the figurehead President of Tuttle Department Stores and the browbeaten husband of Phoebe, likes the dynamo Norman, though―as does Quimby's sexy secretary, Miss Lott (Francesca Bellini)―and does what he can to support the couple...which is difficult, considering the many disasters that hard-working-but-accident-prone Norman creates at the store.
Always a reliable, go-to Jerry Lewis movie whenever it popped up on afternoon and late show movie programs back in the 70s when I was growing up, Who's Minding the Store? may not feature very many of director Frank Tashlin's signature fetishes or obsessions within its surprisingly square, bland framing, but it does have lots and lots of "Tashlin-as-Looney Tunes-animator" moments where he places Jerry in one outrageous, outsized sight gag after another, giving this silly, fluffy outing a consistently high laugh quotient. Released five days after the JFK assassination in 1963 (I wonder if that affected the box office versus other Lewis releases at the time), Who's Minding the Store? was Jerry's next-to-last feature with Tashlin, who, after the uneven The Disorderly Orderly, went on with varying success to work with Tony Randall (the Hercules Poirot flop, The Alphabet Murders), Doris Day (the financially successful The Glass-Bottom Boat and the misfire Caprice), and Bob Hope (the dreadful The Private Navy of Sgt. O'Farrell, Tashlin's last feature). Most admirers of Tashlin would probably agree that by Who's Minding the Store?'s debut, Tashlin had already peaked as a director, with efforts like the ones mentioned above certainly having their inspired moments...while failing to achieve a unified thematic or even visual comedic aesthetic (Who's Minding the Store?'s big, empty frames are surprising next to the crammed, dynamic ones of movies like Will Success Spoil Rock Hunter?, The Girl Can't Help It, Artists and Models, Hollywood or Bust, and The Geisha Boy).
Lewis's great personal triumph from the same year, the genuine masterpiece, The Nutty Professor, completely overshadows Who's Minding the Store?'s impact today obviously, but there's still a lot to like here, chiefly Who's Minding the Store?'s willingness to be essentially nothing more than an extended 90-minute cartoon starring a live-action Jerry Lewis. Written by Tashlin and veteran Harry Tugend, from Tugend's story (Captain January, Little Miss Broadway, A Southern Yankee, Pocketful of Miracles), Who's Minding the Store? takes as its inspiration the funniest sections of the Marx Bros.' The Big Store and expands that narrow framework, using Jerry as a sort of a cross between eager, go-getting Horatio Alger-inspired Harold Lloyd and Looney Tunes' Sylvester, letting Jerry crash around the huge department store, destroying everything in sight in an effort to prove what a hard-working, dependable guy he is for his girl.
That subtext certainly wasn't new for Lewis by this point. The lovable schlub who, by virtue of not being able to do anything right but doing so at a breakneck pace, winning the girl in the process, was a tried-and-true Lewis motif that provided unlimited opportunities for visual sight gags. Here in Who's Minding the Store?, that's about it for story or character motivation, thin as it is, with the added notion that Jerry's soon-to-be-wife, St. John, is going to be "plain and poor," with her place at home, "having babies"―a sentiment agreed with by St. John's henpecked father. You could probably get some mileage out of a discussion of those gender and class stereotypes...if Tashlin or Lewis really cared about such things. However, in Who's Minding the Store?, it's obvious those are just convenient, easy pegs to hang the various sight gags on―sociology and psychology are utilized for jokes, not commentary.
And those jokes work here. For straight laughs, Who's Minding the Store? is one of Jerry's more consistent later efforts. From the opening, when Moorehead views the secret footage of Jerry taken by her private detectives, Tashlin makes it clear he's going for outsized, exaggerated, openly cartoony comedy, and it's delightful, both aurally and visually (the sound of Jerry slurping his soup is pricelessly matched to his mugging, while his being launched from a bent tree is classic toon humor). No Tashlin comedy would be complete without even a little eroticism thrown in there, this time supplied not by St. John as you might expect (or hope) but by the lush, lush Francesca Bellini, who loses her tight pencil skirt during the vacuum cleaner finale, revealing an amazing set of gams on the stacked Bellini (thank you, Frank Tashlin). However, for the most part, the humor is de-sexed by Tashlin's standards, with Tashlin making sure to place countless little bits of family-friendly business in-between the big set pieces to keep you laughing and giggling through the run of the picture.
Throwaways like Jerry watching himself on TV as Ben Casey (discovering too late he's operating without anesthesia), or struggling with Bosley the sheepdog (with Jerry looking worriedly off-camera when the huge hound snaps at him right as Tashlin cuts the scene), or unknowingly eating real fried ants with Fritz Feld (hilarious spooning them into Jerry's mouth), or the funny pile-up caused by Jerry blinding drivers with a huge mirror, are sprinkled throughout the film, keeping us amused as we enjoy the bigger-scaled comedy sequences. The runaway golf ball from the "Futurescope Fairway" machine is quite good, and I particularly like the woman's shoe department scene, where lady wrestler Peggy Mondo insanely jumps up and down on Jerry when he tries to put a size 3 shoe on her size 13 foot. I wish Jerry's trip in a rowboat, courtesy of a shotgun recoil, had been longer (or at least if Tashlin had shown us the resulting crash heard off screen), but Who's Minding the Store?'s finale, the vacuum cleaner sequence, is priceless, a beautifully-designed and executed bit of real special effects (no opticals I could detect) where a vacuum that Jerry tinkers with begins to suck up everything in the store, including the dishes off the shelves and the tiles off the floor. It's remarkably funny, the loud sound effects (like any good cartoon) providing half the laughs, with Tashlin stitching it together expertly; for Lewis fans like myself who grew up on his movies, it's one of our favorite moments from his big-screen features.
Who's Minding the Store?'s supporting cast is a treat, too...even if they have to vie with all that hardware flying around. Jill St. John, one of my all-time favorite Bond girls, is so sweet and light and pretty here you'll be surprised that Tashlin didn't take more advantage of her rather outrageous body and erotic allure. Agnes Morehead, just about to embark on her iconic role in TV's Bewitched, is perfectly bitchy and snappy as the class-conscious, controlling potential mother-in-law of Jerry's ("She can't be that ill!" when seeing footage of her daughter's boyfriend, is a classic), and portly, sweet John McGiver is equally funny as the dithering milquetoast who finally, but nicely, grows a spine. My Favorite Martian's Ray Walston (soon to see his big screen career take a serious hit with his starring role in Billy Wilder's ill-fated bomb, Kiss Me, Stupid) has a lot of fun with his spoof of the harried, dyspeptic Madison Avenue-type big businessman, who nervously puts bromo in his milk, and who's out of breath from his morning three Scotches and chasing his built secretary around the desk ("There's no place in business for a man of character!" he triumphantly announces). As for Jerry, if he looks a little puffy here, a little stiff at times in his Sy Devore-designed "everyman" wear, he more than makes up for it during the big action sequences, where his timing is impeccable as always. Along with the vacuum cleaner finale, fans of Lewis remember the "typewriter" bit from Who's Minding the Store? most readily, where Lewis types along on an imaginary machine while Leroy Anderson's ding-dingy music plays along. It's a typically hilarious, manic Lewis moment, spontaneous and not perfect; Jerry messes up a couple of times but importantly, he goes with it, adding more laughs with his ad-libbed mugging. Critics of Lewis (particularly at this time) pointed to moments like the "typewriter" bit as examples of Lewis' excesses, but for fans, those moments are precisely why he continues to make us laugh.
The DVD:
The Video:
The anamorphically-enhanced, 1.85:1 transfer for Who's Minding the Store? looked a little faded, a little pink to me, with some print damage that didn't help, either. No compression issues, and the image was fairly sharp.
The Audio:
The English mono audio track is serviceable, as expected, with low hiss and no subtitles or closed captions available.
The Extras:
No extras for Who's Minding the Store?, not even a trailer....
Final Thoughts:
Fluffy, silly Jerry Lewis outing, with director Frank Tashlin toning down the fetishisms and upping the cartoon gag quotient. Outings like Who's Minding the Store? may have helped foster the image of later Lewis efforts appealing strictly to kids, since its gag-filled storyline makes it so readily accessible to their sensibilities. Regardless, those jokes and set-pieces are funny, to kids and like-minded adults...and there's nothing wrong with that. I'm highly recommending Who's Minding the Store?.


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text: Final Call for Papers ICFP 2009: International Conference on Functional Programming Edinburgh, Scotland, 31 August - 2 September 2009 http://www.cs.nott.ac.uk/~gmh/icfp09.html ** Submission deadline: 2 March 2009 ** Submission URL: https://www.softconf.com/a/icfp09/ ICFP 2009 seeks original papers on the art and science of functional programming. Submissions are invited on all topics from principles to practice, from foundations to features, from abstraction to application. The scope includes all languages that encourage functional programming, including both purely applicative and imperative languages, as well as languages with objects or concurrency. Particular topics of interest include * Language Design * Implementation * Software-Development Techniques * Foundations * Applications and Domain-Specific Languages * Functional Pearls The conference also solicits Experience Reports, which are short papers that provide evidence that functional programming really works or describe obstacles that have kept it from working in a particular application. Important Dates (at 20:00 UTC) ~~~~~~~~~~~~~~~ Submission: 2 March 2009 https://www.softconf.com/a/icfp09/ Author response: 21-23 April 2009 Notification: 5 May 2009 Final papers due: 8 June 2009 Call for Papers (full text) ~~~~~~~~~~~~~~~ http://web.cecs.pdx.edu/~apt/icfp09_cfp.html Call for Experience Reports (full text) ~~~~~~~~~~~~~~~~~~~~~~~~~~~ http://web.cecs.pdx.edu/~apt/icfp09_cfer.html Program Chair ~~~~~~~~~~~~~ Andrew Tolmach Department of Computer Science Portland State University P.O. Box 751, Portland, OR 97207 USA Email: apt@REDACTED Phone: +1 503 725 5492 Fax: +1 503 725 3211 Mail sent to the address above is filtered for spam. If you send mail and do not receive a prompt response, particularly if the deadline is looming, feel free to telephone.


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Now that the lazy, hazy days of summer are finally here, it's time to think about sun protection--and we're not just talking sunscreen and UV clothing. Whether you're at the beach, the lake, or even the local park, a portable umbrella offers additional protection from the sun's damaging rays. Bonus: It's cooler in the shade.
Our top picks:
Titanium Beach Umbrella $72 (coolibar.com) This 5 foot wide, 7 foot tall umbrella is easy to put together and plant in the ground, folds down to a mere 45 inches, weighs only about 4 pounds, and comes with its own carrying case. The silver outer fabric reflects the UV rays while the green underside fabric absorbs them, making for good sun blockage. And when you come out of the water, it's hard to miss among the sea of striped umbrellas.
PortaBrella $40 (shadeusa.com) If you're always beyond loaded down with stuff, this little guy won't add too much to your burden. Folded down it's only 24 inches long. It too comes inches with a carrying case and is easy to set up.
For a complete list of beach umbrellas see our guide on
Remember that even if you're sitting in the shade of an umbrella, you still need to slather yourself and the kids with sunscreen. For complete information on sun protection read what our GHRI director Miriam Arondhas to say.
Last word of advice: If you hear thunder, pack it up and go!


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Welcome to a wonderland that stretches as far as the eye can see—where you can soak up spectacular sunsets and star-filled nights and the only sound you hear is the whir of the wind and the call of the raven. Immerse yourself in nature–tour historic museums–relax in a hot bath, a luxurious Inn or on a golf course.
Pack your hiking boots–your palette and paints–your camera–your birding books and binoculars–your journal–your star maps–your bike–your tent–your 4WD vehicle. And your cell phone won't work, so don't bother! We guarantee you'll leave your troubles behind after entering our world—America's Outback!
Bicycling is an extremely popular activity in the Death Valley region, allowing active travelers to explore the region in a silent, engaging, low-impact manner on their own or while participating in one of Death Valleys' annual cycling retreats, century rides, or ultra-distance bicycle races.
Wildlife Viewing
Wonderful wildlife can be observed in America's Outback by the respectful traveler. Jackrabbits, cotton tails, ground squirrels, kangaroo rats and other mice and many lizard species are very common. Coyotes and bobcats are also plentiful but less easy to spot. In higher elevations, mountain lion, Dahl sheep, ringtail cats and other species and more are there if you know how to look. Some species, such as the desert pupfish and tortoise are endangered and only found in this area. Please be very respectful of all wildlife, and never offer human food, destroy habitats, or try to touch wildlife. For example, picking up a desert tortoise is guaranteed to result in its death.
Wildflower Viewing
Watching the desert fill with carpets of brilliant wildflowers is an experience unlike any other. Flower seasons are dependent on rains for the previous five months, as well as temperature and wind. Watch the calendar for announcements January through April, with flowers in the higher elevations throughout the summer.
If you love to play tennis, the Furnace Creek Inn has two tennis courts available for guests, and the Furnace Creek Ranch has four. Basketball and vollyball facilities area also available. In Shoshone, courts are available on the High School Grounds, right behind the Shoshone Inn and Shoshone Trailer Park and Camp Ground.
America's Outback is the driest region in the western Hemisphere. However, that won't stop you from swimming! Opportunities range from heated pools (some are natural with geothermal waters) to an open reservoir.
Star Parties
Pristine desert skies, out of range of most light pollution from urban areas, make possible night sky vistas that most people do not experience in a life time. The New Moon phase is the darkest, so bring your telescope or use one of ours.
Night Sky events are offered at Furnace Creek as well Cynthia's Desert Safaris & Lodging
Souvenir Shopping
Gift Shops in America's Outback offer a wide range of enticing merchandise, from polished stones, clothing and jewelry, to Native American and other fine art, fascinating books on local lore, toys and gifts. Healthy products include locally produces clays, soaps and honey, jams and other preserved foods. And don't forget to take home a selection of locally grown dates or date baked goods from China Ranch.
Rock Hounding
It is illegal to remove anything at all from Death Valley National Park or from privately owned lands, so be very aware of where you are. However, on some public BLM lands, you are welcome to search for rocks, whether just a personal favorite or a particular mineral or geological sample you've been pining for. Guide books are available in all Visitor's Centers.
Photographers who visit America's Outback will find themselves overwhelmed by a sense of rapture at the striking variety of subjects to be photographed in this amazing area. From sunrises to sunsets, vast desert to thriving wetlands, wildflowers, wildlife and vignettes of history, there is something for everyone here. In addition to great artists like Ansel Adams, this area has long been used by commercial photographers to capture unique backgrounds for movies and advertisements. Unless you leave the lens cap on, it is hard to take a bad picture here in America's Outback.
Enthusiasts of sail planes and paragliders have enjoyed some spectacular flights in America's Outback. However, flying here is a serious proposition — it is not for beginners. There is no support available — you are on your own! Winds are gusty and highly unpredictable. Spring and Fall offer the best flying conditions, but the winter months can offer calmer conditions better suited to training for the less experienced.
Off-Road Vehicles
Off road vehicles are not permitted anywhere within the Death Valley area. This is a fragile landscape that takes years to recover! Wagon tracks from the Old Spanish Trail are still visible for miles. Off road recreation is offered in Amargosa Valley, Nevada, to the north and at Dumont Dunes, south of Tecopa. Contact the BLM for more information.
Museums in America's Outback come in many shapes and forms: Museums, Visitor and Interpretive Centers, Murals, Walking Tours, Driving Tours and the historic towns that provide a region-wide journey in the area's history. The Shoshone Museum and the Borax Museum (Furnace Creek) both have indoor and outdoor displays. Try Shoshone's Walking tour, and don't miss the Post Office Mural. Death Valley National Park and the Ash Meadows National Wildlife Refuge both offer Interpretive Centers. Many other destinations also offer excellent historic displays and interpretations.
Motor Touring
Discover the back roads of America's Outback, secret scenic locations, untouched historical sites and roads less traveled. Many wonderful locations are fine for the average vehicle, while others require higher clearance or even four-wheel drive. Consult with your host at all lodging facilities, or pick up an excellent guide for the area of your choice at either Visitor's Center.
Interpreted Trails
To help you make the most of your adventure and ensure that you don't miss anything important, some destinations have developed signs along their walks or trails to inform you about everything from plant and animal species to special vistas and historical highlights.
Hot Springs Soak
The hot springs of Tecopa are famous throughout the world for their healing properties. Lean back, let the water swirl around you and feel relaxation like you've never felt before. Chose from a variety of venues, each with their own unique support services, such as massage, aroma therapy and more.
Horseback Riding
For the horse lover, Death Valley can offer a wonderful experience and unfettered vistas. Horseback Riding & Carriage Rides are available at the Furnace Creek Ranch seasonally, October – May.
History Events
November is the best time for History events, beginning with Shoshone's Old West Days (1st November weekend) and continuing through the 49ers Encampment at Furnace Creek. However, keep your eye on the Calendar for the Death Valley History Conference and other special events.
Opportunities abound in America's Outback for hikers of every skill level. So pack your water bottle and camera, and head out in almost any direction. Most of the county is made up of National Forest, BLM, or National Park Service protected areas. Guide books and maps are available at both Visitor's Centers, and almost anyone you meet can offer suggestions. The desert can be a dangerous place, so do be sure to consult with someone before setting out, and leave word of where you will be. Many destinations also offer interpreted trails, to keep you in the know as you go.
It may be difficult to keep your mind on your game with the beautiful Panamint Range and other expansive Death Valley vistas as a backdrop. However, if you're game, the lowest course in the U.S. can be found at Furnace Creek in Death Valley.
Children's Playgrounds
While traveling with children, a playground is always a welcome site. Wonderful playgrounds are available at the Furnace Creek Ranch, and at the Tecopa Hot Springs County Park, within walking distance of local lodging.
America's Outback has a wide variety of campgrounds, with camping facilities available in each of the main communities. Outlying areas can also be reached as day trips. The Wild Rose Campground, high up in the park, is wonderful when lower sites are heating up.
Bird Watching
Located on many major routes, migratory birds can be viewed in great numbers during spring and fall months in America's Outback, especially March and April. They can be observed in canyons, near springs and throughout area wetlands in the region. Over 100 species have been documented at China Ranch alone. Other species take advantage of unique habitat features and stay year round.
Biking/MT Biking
Many spectacular places can be enjoyed from a bicycle in America's Outback. Within Death Valley National Park, a bike lane is provided in the Furnace Creek area. All other paved roads in the region are narrow two-lane roads without shoulders. Many are frequented by commercial vehicles and RVs, so we recommend caution when sharing these roads. However, there are hundreds of miles of dirt roads throughout the Death Valley, Shoshone and Tecopa area, where bikers can enjoy vast vistas, wildlife and the sound of the wind. Don't forget your water!
Art Galleries & Culture
Enjoy the wide range of individual expression inspired by America's Outback, whether in the corridors of the Furnace Creek Inn, or ot the Tecopa Basin Artist Group's Galley (at the Tecopa Hot Springs Resort), or enjoying an organ performance at Scotty's Castle or at the one-of-a-kind Amargosa Opera House.


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This article provides an historical examination of American Constitutional law concerning religion as it has evolved through three periods: the Mormon period of the late nineteenth century; the religious pluralism period of post-WW2 decades; and the multiculturalism period that began around 1990 and that remains underway. It examines Supreme Court interpretations of First Amendment provisions pertaining to religion, and it contextualizes those interpretations to explore their implications for women's liberty and equality at each of the three periods. Its argument is that Constitutional doctrine relating to religion – through its multiple doctrinal reversals – has consistently entailed and depended upon negative constructions of women, sacrificing women's liberty and equality interests in order to prefer and to cultivate the liberty and equality interests of churches.
Thursday, April 12, 2012
Ashe on Women, Free Exercise, and Establishment in American Law
1 comment:
- Shag from Brookline said...
My interest in reading this article was piqued by the reference to the Mormon period of the late 19th century which I thought might be relevant to the 2012 presidential campaign with Mormon Mitt Romney as the putative Republican candidate. The author is critical of the Supreme Court's decision in Reynolds "outlawing" polygamy in interpreting the First Amendment's "free exercise" clause as ignoring or limiting women's rights. The author uses this Mormon period as the foundation of her theme, going through subsequent periods, to demonstrate the impact of the Court's subsequent decisions on women's rights that utilize the First Amendment's religion and speech clauses in manners limiting women's rights.
While I agree with Prof. Ashe's basic theme that women's liberty and equality interests are sacrificed, I wonder what the interpretation of the religion clauses would look like if in Reynolds the Court had decided that the polygamy prohibition infringed upon the free exercise clause.
Perhaps if women had had equal rights at the time, a woman might have been dominant in polygamy resulting in multiple husbands.
In her Conclusion, Prof. Ashe references the then pending appeal before the Court on Hosanna-Tabor Evangelical. The Court's decision earlier this year serves as another limitation on women's liberty and equality interests by means of the "ministerial exception" relied upon the Court in the termination of a female employee.
- April 15, 2012 at 6:16:00 AM EDT


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PARIS, July 9, 2012 /PRNewswire/ -- Inspiration Biopharmaceuticals, Inc. (Inspiration) today reported data from its ongoing Phase 2/3 study evaluating the efficacy of OBI-1, an investigational recombinant porcine factor VIII (FVIII), for the treatment of serious bleeds in people with acquired hemophilia A. According to the interim analysis, seven out of seven trial participants receiving OBI-1 experienced control and subsequent resolution of their bleeds. Edward Gomperts, MD, Attending Hematologist and Director of Clinical Research, Clinical Investigation Center at Children's Hospital Los Angeles and Consultant to Inspiration, presented the findings in an oral presentation at the 2012 World Federation of Hemophilia (WFH) World Congress in Paris.
Acquired hemophilia A is a rare, sometimes life-threatening bleeding disorder that is caused by the development of autoantibodies (inhibitors) against FVIII, a key protein contributing to normal coagulation of blood. The antibodies render the native factor VIII ineffective in promoting clotting. Treatment of acquired hemophilia can be challenging, because the antibodies will attack any human form of FVIII. OBI-1 is designed to avoid recognition by antibodies to human FVIII. People with inhibitors to human FVIII may respond to porcine FVIII, replacing the missing step in their coagulation cascade."People with acquired hemophilia currently have limited treatment options to control serious bleeding episodes. These preliminary findings are encouraging and suggest that further investigation of the efficacy and safety of OBI-1 in this population is warranted," said Dr. Gomperts.
A second Accur8 Phase 2/3 clinical trial is also underway to evaluate OBI-1's ability to control bleeding in people with congenital hemophilia A with inhibitors and the safety of this drug in this population.
As part of Inspiration's expanded presence at the WFH World Congress, the company will host a symposium tomorrow entitled, "Hemophilia B: The Neglected Hemophilia," featuring a panel of experts exploring advancements in research, treatment and advocacy for hemophilia B, which is far less prevalent than hemophilia A.
Inspiration has a second product under development, which is a recombinant factor IX therapy being evaluated for the prevention and treatment of bleeding in people with hemophilia B and its safety profile in this population. This product is currently under regulatory review in both the U.S. and the EU.
"We are thrilled to be growing our presence and involvement at the WFH annual congress, the premier global scientific gathering for the hemophilia community," said John P. Butler, Chief Executive Officer of Inspiration. "Our goal as a company centers on broadening treatment choices, expanding global access to therapies and advancing innovation for people with all types of hemophilia. This meeting gives us an opportunity to connect face-to-face with leaders in the global hemophilia community, discuss their ongoing needs and determine the role Inspiration can play in improving the lives of people with hemophilia around the world."
Study Design and ResultsThe Accur8 Auto-antibody trial is an ongoing prospective, open label, Phase 2/3 study. The primary objective of the study is to evaluate the efficacy of OBI-1 treatment for serious (life- or limb-threatening) bleeds in individuals age 18 and older with acquired hemophilia A, as measured by the control of bleeding 24 hours after initial OBI-1 dose administration.
The interim analysis presented today included data from the first seven trial participants with severe bleeds not controlled with bypassing agents who were enrolled and treated with OBI-1. To date, 15 subjects have been enrolled and completed treatment in the clinical trial. Participants received 200U/kg of OBI-1 on first injection and were subsequently dosed based on target FVIII levels. All seven subjects experienced successful control of bleeds at 24 hours and subsequent resolution of their bleeds. Therapeutic FVIII activity levels were achieved and maintained with intermittent OBI-1 administration based on FVIII levels. Of the adverse events reported during the study thus far five were serious, but these were not considered by investigators to be treatment-related. As part of the ongoing Accur8 Auto-antibody trial, adverse event data continues to be collected including the evaluation of inhibitors to porcine factor VIII.
About Inspiration BiopharmaceuticalsAs the only biopharmaceutical company dedicated solely to hemophilia, Inspiration is committed to improving the care of people with this condition by broadening treatment choices, expanding global access to care and advancing innovative therapies. Founded by two families whose sons have hemophilia, Inspiration is inspired to make a difference in the lives of people impacted by hemophilia around the world.
Inspiration's lead product candidates are OBI-1 and IB1001, an investigational intravenous recombinant factor IX being developed for the treatment of hemophilia B.
For more information about Inspiration Biopharmaceuticals, please visit www.inspirationbio.com.Contacts: MediaCompanyKate LewisGordon H. BusenbarkFeinstein Kean HealthcareSenior Vice President, Chief Financial OfficerTel: +1-617-577-8Tel: +1-617-588-1802Email: email@example.com
|SOURCE Inspiration Biopharmaceuticals, Inc.
Copyright©2012 PR Newswire.
All rights reserved


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