text:
June 18, 2016 8:00 am
Church of the Pacific, 5-4280 Kuhio Highway, Princeville
5-4280 Kuhio Highway, Princeville
It's the place to be when you're looking for a Hawaii made product. Shop with confidence and enjoy the wide array of local Kauai artisans and crafters that the Kauai Island Crafters Fair bring to their events. Each artisan and crafter showcases their high standards of quality made craftsmanship into their work. Fine products like Niihau & sunrise shell jewelry, bone & wood carvings, paintings & prints, note cards, sun catchers, American & Hawaiian quilts & futons & blankets, sewn gifts, silk floral arrangements, fragrant floral soaps, wearable art, Hawaiian dolls, hakus & hairclips, Hawaiian tapa prints & bags just to name a few.
Proceeds to benefit the Church of the Pacific.
At Church of the Pacific, 5-4280 Kuhio Highway, Princeville.
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text:
Boy crushed at rotating Atlanta restaurant
- Author: Angelo Rivera Apr 16, 2017,
Apr 16, 2017, 0:38
After wandering from the window table where he was seated with his parents, the boy got caught between the wall and a table, Atlanta police spokeswoman Officer Stephanie Brown told the (Atlanta) Journal-Constitution.
"His whole body was caught in between maybe four or five inches of space, and his head took the brunt of the injury", said Sgt. Warren Pickard of the Atlanta Police Department.
The boy and his family were visiting from Charlotte and were at the restaurant for lunch, it said.
The floor automatically stopped as it is created to do when something is caught. "A small child doesn't know what to do in those moments". "Pulling furniture, turning over tables, trying to administer first aid, but just want not successful in saving the child's life", Pickard added, terming it as a "very tragic incident".
The unconscious boy was rushed to Grady Memorial Hospital, where he later died.
The restaurant will be closed for the Easter weekend because of the boy's death, CNN affiliate WGCL-TV in Atlanta reported.
The hotel's manager, George Reed, issued a statement offering condolences to the family. Our thoughts and prayers are with his family.
In a statement, the owner of the restaurant, George Reed, said "words can not express the depths of our sorrow".
The Sun Dial revolving restaurant and cocktail lounge opened in 1976, and offers 360-panorama views from the 72 stories above street level, according to its website.

subset: commoncrawl


text:
- Research article
- Open Access
Spartin activates atrophin-1-interacting protein 4 (AIP4) E3 ubiquitin ligase and promotes ubiquitination of adipophilin on lipid droplets
© Hooper et al; licensee BioMed Central Ltd. 2010
- Received: 1 March 2010
- Accepted: 26 May 2010
- Published: 26 May 2010
Spartin protein is involved in degradation of epidermal growth factor receptor and turnover of lipid droplets and a lack of expression of this protein is responsible for hereditary spastic paraplegia type 20 (SPG20). Spartin is a multifunctional protein that associates with many cellular organelles, including lipid droplets. Recent studies showed that spartin interacts with E3 ubiquitin ligases that belong to the neural precursor cell-expressed developmentally downregulated gene (Nedd4) family, including atrophin-1-interacting protein 4 (AIP4/ITCH). However, the biological importance of the spartin-AIP4 interaction remains unknown.
In this study, we show that spartin is not a substrate for AIP4 activity and that spartin's binding to AIP4 significantly increases self-ubiquitination of this E3 ligase, indicating that spartin disrupts the AIP4 autoinhibitory intramolecular interaction. Correspondingly, spartin has a seven times higher binding affinity to the WW region of AIP4 than the binding of the WW region has to the catalytic homologues of the E6-associated protein C-terminus (HECT) domain, as measured by enzyme-linked immunosorbent assay. We also show that spartin recruits AIP4 to lipid droplets and promotes ubiquitination of lipid droplet-associated protein, adipophilin, which regulates turnover of lipid droplets.
Our findings demonstrate that spartin acts as an adaptor protein that activates and recruits AIP4 E3 ubiquitin ligase to lipid droplets and by this means regulates the level of ubiquitination of adipophilin and potentially other lipid-associated proteins. We propose that this is one of the mechanisms by which spartin regulates lipid droplet turnover and might contribute to the pathology of SPG20.
- Lipid Droplet
- Hereditary Spastic Paraplegia
- HECT Domain
- Spartin
- PreScission Protease
The hereditary spastic paraplegias (HSPs) are inherited neurological disorders characterized by progressive spasticity and muscle weakness in the lower limbs [1]. Troyer syndrome is an autosomal recessive HSP caused by a frameshift mutation in the spartin gene (SPG20) [2], resulting in a loss of expression of the mutated protein [3].
Spartin harbors a microtubule-interacting and trafficking (MIT) domain and a plant-senescence domain at its N-terminus and C-terminus, respectively [4]. The latter domain was suggested to be responsible for spartin's association with lipid droplets in cells incubated with oleic acid [5]. Spartin has a multifunctional role in cells as evidenced by its association with membranes of several cellular organelles [5, 6] and its interaction with many binding partners [7]. Thus far is it known that spartin is important in the trafficking of epidermal growth factor receptors [6, 8] and in the turnover of lipid droplets [5]. Lipid droplets contain a neutral lipid core surrounded by a monolayer of polar lipids. The membrane layer of the lipid droplet has two major groups of proteins: enzymes important in lipid metabolism and the perilipin, adipophilin, and 47-kDa tail interacting protein (PAT) family of peripheral membrane proteins involved in stabilizing lipid droplets [9].
Spartin is known to be ubiquitinated and interacts with several E3 ubiquitin ligases that harbor a homologous to E6-associated protein C-terminus (HECT) domain. These ligases belong to the neural precursor cell-expressed developmentally downregulated gene (Nedd4) family and include atrophin-1-interacting protein 4 (AIP4) [8, 10] and atrophin-1-interacting protein 5, also known as the WW domain-containing E3 ubiquitin protein ligase 1 (AIP5/WWP1) [5, 8]. Although previous studies have shown that AIP5 is responsible for ubiquitination of spartin and removes spartin from the lipid droplets [5], a recent report demonstrated that depletion of AIP4 and AIP5 had no effect on spartin's ubiquitination [8]. Furthermore, the importance of the interaction between spartin and E3 ubiquitin ligases with the HECT domain remains unknown.
In this study, we provide evidence that spartin is not ubiquitinated by AIP4; rather, spartin acts as an adaptor protein that, through binding to AIP4, increases the enzymatic activity of this E3 ligase by releasing AIP4 from its autoinhibited state. We also demonstrate that spartin recruits AIP4 to lipid droplets and is a necessary adaptor protein for polyubiquitination of adipophilin on lipid droplets. This might be one of the mechanisms by which spartin regulates the turnover of lipid droplets.
Ubiquitination levels of spartin are not altered by AIP4
Previous studies showed that spartin interacts with AIP2 (also known as WW domain-containing protein 2 (WWP2)), AIP4, and AIP5 through its PPAY motif [5, 8]. However, there is a discrepancy between previous studies: one found that spartin is a substrate of AIP4 and AIP5 E3 ligases [5], but another found that spartin is not a substrate of those ligases [8]. To resolve this discrepancy, we used an in vivo ubiquitination assay to investigate the ubiquitination status of spartin in cells overexpressing ubiquitin together with either wild-type or enzymatically inactive AIP4. Specifically, we examined the conjugation of hemagglutinin (HA)-tagged ubiquitin into Myc-spartin that had been immunoprecipitated from HeLa cells cotransfected with ubiquitin and spartin together with either Flag-AIP4 or Flag-AIP4C830A.
The interaction between spartin and AIP4 or AIP5 is mediated by spartin's PPAY motif. When the PPAY motif within spartin was mutated to PAAA, it abrogated the interaction with AIP5 and AIP4 ([5, 8] and this study). One report found that this mutation resulted in the loss of ubiquitination of spartin [5], but Edwards and colleagues [8] reported that this mutation had no effect on the levels of spartin's ubiquitination. To resolve these contradictory results, we further examined the ubiquitination levels of spartin after preventing its binding to AIP4 by mutating the PPAY motif or using the fragment of spartin depleted of its N-terminus containing the PPAY motif. We overexpressed HA-wild-type spartin, HA-mutant spartin PY/AA (in which PPAY motif was mutated to PAAA) or HA-tagged spartin fragment 211-666 (which lacks the PPAY motif) together with Flag-ubiquitin in HeLa cells. As shown in Figure 1b, overexpressed spartin PY/AA and the spartin fragment (211-666) were both monoubiquitinated and polyubiquitinated to the same extent as the wild-type spartin. Neither overexpressed spartin PY/AA nor the spartin fragment (211-666) interacted with AIP4 (Figure 1c). We summarized the association of different spartin constructs with AIP4 and their ubiquitination status in Figure 1d. Overall, our results indicate that the levels of spartin's ubiquitination are not affected by its association with AIP4.
Spartin recruits AIP4 to endogenous lipid droplets
We also found that HA-wild-type spartin but not mutant spartin PY/AA sequestered AIP2 to the lipid droplets (Additional file 1). These results reveal that spartin is an adaptor protein that recruits AIP2 and AIP4 to the lipid droplets.
Spartin increases the activity of AIP4 in vivo and in vitro
To further investigate the role of spartin as an adaptor protein in binding with AIP4, we examined whether, in addition to recruiting AIP4 to lipid droplets, spartin also enhances its enzymatic activity. It has been shown that, because of the presence of the catalytic HECT domain, the level of self-ubiquitination of AIP4 is a good measure of its enzymatic activity [11, 12].
Furthermore, we examined whether binding of wild-type spartin to AIP4 in vitro also results in increased self-ubiquitination of AIP4. We investigated the levels of self-ubiquitination of the glutathione S-transferase (GST)-AIP4ΔC2 protein in the absence of spartin or in the presence of spartin fragments 155-367 or 155-367 PY/AA. We used these spartin fragments because they are easily expressed in bacteria. We used AIP4 lacking the C2 domain because this protein contains all necessary domains for its autoinhibition and is well expressed in bacteria [11]. As shown in Figure 3b (lane 2), in the absence of spartin, AIP4ΔC2 was self-ubiquitinated at low levels in the presence of all necessary components for in vitro ubiquitination. When spartin 155-367 was added to the reaction, self-ubiquitination of AIP4ΔC2 increased significantly as detected by anti-ubiquitin antibodies (Figure 3b, lane 3, top panel). In the presence of spartin, a high molecular weight smear was also detected when we used anti-ITCH antibodies (Figure 3b, lane 3, second panel from the top). In contrast, in the presence of mutant spartin 155-367 PY/AA, AIP4ΔC2 was ubiquitinated at the same low levels as in the absence of spartin (Figure 3b, lanes 4 and 2, respectively). The results from in vitro and in vivo ubiquitination experiments demonstrate that spartin's binding to AIP4 significantly increases the catalytic activity of this E3 ligase.
Spartin promotes polyubiquitination of adipophilin on lipid droplets
Although spartin is not ubiquitinated by AIP4, by recruiting AIP4 to lipid droplets and increasing its activity, spartin might place AIP4 in the vicinity of its substrate(s). One of those substrates might be adipophilin, also known as adipose differentiation-related protein (ADRP), which has been shown to be polyubiquitinated [13]. To examine the levels of ubiquitination of adipophilin in the absence of AIP4, AIP5, and AIP2, we did not attempt to knock down AIP4, AIP5, and AIP2 simultaneously in cells because depletion of two of these E3 ubiquitin ligases results in cell death [14]. Using immunofluorescence, we determined that spartin colocalizes with HA-adipophilin on lipid droplets (Additional file 2). Thus, we tested whether spartin-mediated recruitment of Nedd4 E3 ubiquitin ligases to lipid droplets might be responsible for the polyubiquitination of adipophilin. We found that spartin cells treated with small interfering RNA (siRNA) showed significantly less polyubiquitination of adipophilin compared with control siRNA-treated cells (Figure 3c). This suggests that spartin-mediated recruitment of Nedd4 E3 ligases to lipid droplets might be responsible for ubiquitination of adipophilin in HeLa cells.
Binding of spartin to AIP4 disrupts the proline-rich region (PRR)/WW-HECT complex
Other researchers have suggested that the enzymatic activity of AIP4 is autoinhibited by the intramolecular interaction of its HECT domain with the region between the proline-rich region and the WWIV domain [11, 12]. Furthermore, we showed that spartin-mediated binding to AIP4 increases its self-ubiquitination, implying that spartin releases AIP4 from its autoinhibited state. To assess the inhibitory interactions of AIP4 directly, we purified the PRR/WWI-IV region and the HECT domain of AIP4 and used the intermolecular PRR/WW-HECT complex to mimic the autoinhibited state of AIP4; then we examined whether spartin's binding to AIP4 disrupts this complex. We sought to quantitatively measure the binding affinity between the PRR/WWI-IV region and the HECT domain of AIP4.
Hereditary spastic paraplegias, such as Troyer syndrome, are neurodegenerative diseases characterized by progressive weakness and spasticity in the lower limbs [1]. A nucleotide deletion (1110delA) in spartin (SPG20) causes autosomal recessive Troyer syndrome [2]. Previously, we demonstrated that this mutation results in a complete loss of spartin and postulated that Troyer syndrome has a loss-of-function disease mechanism [3].
Recently, it has been shown that spartin is involved in turnover of lipid droplets by an unknown mechanism [5]. These findings suggested that there is a link between lipid droplet turnover and the pathology of Troyer syndrome. In the present studies, we investigated a molecular mechanism for spartin-dependent regulation of lipid droplet turnover. This novel pathway, which we call SPAA, involves spartin, the E3 ubiquitin ligase AIP4, and a major lipid droplet protein, adipophilin.
Our study provides molecular and biochemical evidence that spartin is not ubiquitinated by AIP4 but acts as an adaptor protein for this E3 ubiquitin ligase. We determined that spartin markedly increases self-ubiquitination of AIP4 through PPAY-mediated binding and recruits it to the lipid droplets. We also demonstrated that spartin promotes ubiquitination of adipophilin, a lipid-associated protein that is known to affect triacylglycerol turnover [15].
We have shown that spartin, through its PPAY motif, sequesters AIP2 and AIP4 to endogenous lipid droplets. This finding contrasts with that of previous studies that showed decreased accumulation of YFP-spartin on lipid droplets (stimulated with 500 μM of oleic acid) by overexpressed Cherry-AIP5 [5]. One possible explanation for this discrepancy is that the induction of lipid droplets with a high dose of oleic acid and the large fluorescence tags fused to both spartin and AIP5 significantly altered the dynamics of those proteins.
We demonstrated that spartin facilitates ubiquitination of adipophilin, a lipid droplet-associated protein. It has been shown that adipophilin is polyubiquitinated and then degraded by a proteasome-dependent pathway [13]. Ubiquitination is one of the mechanisms by which the stability of adipophilin is regulated [13], and its level of ubiquitination seems to be regulated by spartin-mediated recruitment of Nedd4 E3 ubiquitin ligases to lipid droplets (Figure 5). Because adipophilin decreases triacylglycerol turnover [15, 17], we propose that spartin affects lipid droplet turnover ([5], and this study) (Additional file 4) by regulating the level of ubiquitination of adipophilin and perhaps other lipid droplet-associated proteins. We call this molecular mechanism the SPAA pathway for lipid droplet turnover.
Impaired lipid droplet metabolism might be one of the mechanisms in the pathogenesis of Troyer syndrome. Malfunction of proteins involved in lipid maintenance is considered to be a cause of some neurological disorders [18]. For example, an autosomal-dominant hereditary spastic paraplegia, HSP17, which is characterized by muscle weakness in upper limbs and spasticity of lower limbs, is caused by a mutation in the Berardinelli-Seip congenital lipodystrophy 2 (BSCL2) gene encoding seipin [19]. Seipin has been shown to maintain the physiological morphology and size of lipid droplets in yeast [20]. A large number of lipid droplets in atrophic α motor neurons have been reported in hereditary porcine neuronal degeneration [21]. Now, based on the SPAA pathway for lipid droplet turnover, we can begin unraveling the specific biological role of spartin in Troyer syndrome.
In summary, spartin is not a substrate for AIP4 E3 ubiquitin ligase. Instead, spartin acts as a classic adaptor protein that recruits AIP4 to lipid droplets and increases its enzymatic activity. In addition, spartin acts as a linker for ubiquitination of adipophilin on lipid droplets, likely by sequestering Nedd 4 E3 ubiquitin ligases and ubiquitination machinery. These might be one of the mechanisms by which spartin regulates lipid droplet turnover and which may contribute to the pathophysiology of SPG20.
Antibodies and reagents
The following antibodies were used: rabbit polyclonal anti-hemagglutinin (HA; Abcam, Cambridge, MA, USA), mouse monoclonal anti-HA (12CA5; Covance, Princeton, NJ, USA), rabbit polyclonal anti-Myc, mouse monoclonal anti-Flag conjugated to horseradish peroxidase (HRP) (clone M2; Sigma, St. Louis, MO, USA), mouse monoclonal anti-ITCH (BD Biosciences, San Jose, CA, USA), mouse monoclonal anti-ubiquitin P4D1 (Cell Signaling, Danvers, MA, USA), and rabbit polyclonal anti-glutathione S-transferase (GST) (Santa Cruz, Santa Cruz, CA, USA). The rabbit anti-spartin antibody was used as described previously [22]. The anti-mouse and anti-rabbit antibodies conjugated to HRP were from Thermo Fischer Scientific (Waltham, MA, USA). Secondary goat anti-mouse and anti-rabbit Alexa Fluor 568-conjugated or 633-conjugated antibodies were from Invitrogen (Carlsbad, CA, USA)
Mammalian expression vectors
The full-length human spartin cDNA in the pGW1-HA and pGW1-Myc expression vectors have been described previously [6]. Flag-AIP4 in a pCMV-10 vector was a gift from Adriano Marchese (Loyola Chicago University, Maywood, IL, USA). To generate the pGW1-HA spartin 211-666 construct, residues 211-666 of human spartin were amplified by PCR using PfuTurbo (Agilent Technologies, Santa Clara, CA, USA) and cloned in frame into an EcoRI site of the pGW1-HA vector. To generate spartin PY172,174AA and Flag-AIP4C830A, site-directed mutagenesis was applied using the QuickChange protocol (Agilent Technologies). We refer to mutant spartin PY172,174AA as spartin PY/AA. HA-adipophilin was obtained from GeneCopoeia (Rockville, MD, USA). The Flag-AIP2 vector was a gift from Richard Longnecker (Northwestern University, Evanston, IL, USA).
Bacterial expression vectors
The pGEX-4T2 with each WW domain I, II, III, IV and pGEX-4T2 with HECT domain were gifts from Adriano Marchese (Loyola Chicago University). A vector expressing GST-AIP4ΔC2 was a gift from Annie Angers (University of Montreal, Montreal, Canada). The pGEX6p-1-PRR-WWI-IV (155-486) vector was generated by PCR using full-length AIP4 as a template. To generate pGEX6p-1-wild-type spartin 155-367 or pGEX6p-1-spartin 155-367 PY172,174AA, human spartin was amplified by PCR using either wild-type or mutant spartin cDNA as a template.
Cell culture and transfections
HeLa cells were maintained in Dulbecco's modified Eagle's medium (Invitrogen) supplemented with 10% fetal bovine serum (Gemini BioProducts, West Sacramento, CA, USA). The transfections with plasmids or plasmids together with control siRNA or spartin siRNA [6] were performed using the TransIT-HeLaMONSTER transfection kit (Mirus, Madison, WI, USA) and Lipofectamine 2000 (Invitrogen), respectively.
HeLa cells were grown on glass cover slips, transfected, and processed as described previously [23]. Cover slips were mounted with ProLong Antifade reagent (Invitrogen) and imaged using a Zeiss LSM-510 confocal microscope (Zeiss, Maple Grove, MN) with a 63 × 1.4 NA Plan Apochromat oil immersion objective at 1024 × 1024 resolution. The images were processed with Adobe Photoshop 7.0 software (Adobe, San Jose, CA, USA).
Image analysis
For each specified immunofluorescence condition, 30 cells that showed overexpressed proteins were analyzed at random, and colocalization was assessed with line scans using Zeiss software. A total of 90 cells were analyzed in 3 independent experiments. The data are represented as the percentage of cells that show colocalization of immunostained, overexpressed proteins with lipid droplets.
In vitroubiquitination
The assays were conducted in reaction buffer with reagents that were described previously [11] and with 1-2 μg of GST-AIP4ΔC2 alone or together with spartin 155-367 wild-type or spartin 155-367 PY172,174AA proteins, both of which were cleaved of their GST tag by using PreScission protease (GE Healthcare, Waukesha, WI, USA). The samples were incubated for 60 min at 37°C and analyzed by immunoblotting using anti-ubiquitin and anti-ITCH antibodies.
In vivoubiquitination
Transfected HeLa cells were washed twice with ice-cold phosphate-buffered saline (PBS) and lysed with buffer containing 20 mM Tris, 150 mM NaCl, 1% Triton X-100, 10 mM N-ethylmaleimide, and protease inhibitors. Cell lysates were denatured with 1% SDS, boiled for 5 min, and diluted 14 times with lysis buffer to lower the concentration of SDS before immunoprecipitation. For in vitro ubiquitination of HA-ADRP in cells treated with control or spartin siRNA, cells were treated with 300 μM of oleic acid overnight and then subsequently with MG132 for 3 h.
The following plasmids were used to express proteins in bacteria: pGEX-4T2-HECT, pGEX6p-1-PRR-WWI-IV, pGEX6p-1-wild-type (WT) spartin 155-367, and pGEX6p-1-spr 155-367 PY/AA. Proteins were purified as described previously [24]. We applied PreScission protease (GE Healthcare) to remove the N-terminal GST tag from GST-PRR/WWI-IV, GST-WT spartin 155-367, and GST-spartin 155-367 PY/AA. All proteins were dialyzed using PBS. ELISA microplates (96 well; BD Biosciences) were coated with 50 ng of PRR/WWI-IV per well in 10 mM phosphate buffer (pH 7.4) and incubated overnight at 4°C. After washes and blocking, serially diluted samples of GST-WT spartin 155-367, GST-spartin 155-367 PY/AA, or GST-HECT were added, and the plates were incubated for 2 h. The plates were washed with PBS and then incubated for 1 h with rabbit anti-GST. After the washes with PBS and 0.05% Tween 20, the plates were incubated with a 1:1,000 dilution of anti-rabbit HRP conjugated antibodies for 1 h. After washes with PBS, the color was developed with 3,3'5,5'-tetramethylbenzidine (Thermo Fisher Scientific) for 5 min, and the optical density was read at 630 nm. The assays were performed in triplicate. Prism 5 (Graphpad Software, La Jolla, CA, USA) was used to analyze binding data. For competition ELISA, 5 μM of GST-HECT was incubated with serially diluted WT spartin 155-367 or spartin 155-367 PY/AA in wells coated with 50 ng of PRR/WWI-IV. The amount of bound GST-HRP was detected using anti-GST antibodies.
Analysis of ELISA data
The IC50 and Kd were calculated by fitting the data points with either the one-site binding curve AU = AU0 × ((GST-protein)/((GST-protein) + Kd) or the competitive binding curve %GST-HECT-binding = Min + (Max - Min)/(1 + 10((WT spartin) - log(IC50)), where AU (AU0) is the ELISA (maximal) absorption reading, (GST-protein) is either the GST-HECT or GST-WT spartin 155-367 concentration, (WT spartin) is the WT spartin 155-367 concentration, and Min(Max) is the minimal (maximal) percentage of GST-HECT binding. The inhibition constant, Ki, was calculated by using the equation Ki = IC50/(1 + (GST-HECT)/Kd) [25] based on an IC50, concentration of bound GST-HECT, (GST-HECT) = 5 μM, and GST-HECT binding affinity for PRR/WWI-IV, Kd = 2 μM.
This work was supported by National Institutes of Health grant K22NS050137 (to JCB) and by American Diabetes Association Career Award ADA 1-06-CD-23 (to AS). We would like to thank Jessica DeMaio for assistance with preparation of DNA of plasmids.
Authors' Affiliations
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- Bhandari D, Trejo J, Benovic JL, Marchese A: Arrestin-2 interacts with the ubiquitin-protein isopeptide ligase atrophin-interacting protein 4 and mediates endosomal sorting of the chemokine receptor CXCR4. J Biol Chem. 2007, 282: 36971-36979. 10.1074/jbc.M705085200.View ArticlePubMedGoogle Scholar
- Cheng Y, Prusoff WH: Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction. Biochem Pharmacol. 1973, 22: 3099-3108. 10.1016/0006-2952(73)90196-2.View ArticlePubMedGoogle Scholar
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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Nothing seems to sap my blogging mojo like moving, but I'm trying to get back into the habit by tackling some projects I've been meaning to try. Most of my craft supplies are in storage indefinitely, so I decided to make a tabletop terrarium because I had everything on hand except for the container, which I bought at a Goodwill for $2. I collected all of the plants and moss and the empty snail shell in a walk around my parents' large yard.
I guess if I only fulfill one of my resolutions for 2012, "Make more terrariums" is as good as any.


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Moitrayee completed Master of Arts in History from Jadavpur University. She also earned Certificate in Creative Writing from the University of Oxford. Also A in History from Loreto College, Kolkata. She is currently working as a content consultant with organizations in the IT space. She has previously worked with IBM India, Oracle ...Read More »
Home / Tag Archives: Moitrayee Bhaduri


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What better way to get amped up for Acquia Engage than with an exclusive learning experience? Due to the tremendous success we had over the last couple of years, we will be hosting pre-conference workshops again this year. We look forward to welcoming our registered Engage attendees for some pre-conference workshops, and get some great guidance in Digital Portfolio Assessment, Personalization & Content Best Practices, as well as Decoupled Drupal and Multisite Governance leveraging our suite of Acquia products.
The cost for training is $150 per full-day session (in addition to the general event registration fee). Check out the specifics below, and register today. But hurry, participation in the workshops is limited!
Register Now
Sign up for one of three full-day workshops:
Pre-Conference Workshop Tracks
Driving Engagement Throughout the Customer Journey
Digital Portfolio with Bryant Shea
Acquia Lift: Incorporating Personalization into Your Digital Program
Acquia Journey
Building for the Future of Digital Experiences
Decoupled Drupal with Preston So
Continuous Delivery with Dane Powell
Multisite Governance with Jeff Reed, Jenni Lee and Mark Sakurada
Enabling Accessibility
Accessibility Training (with certificate of completion) with Danielle Sheffler
Event Logistics
Date: Wednesday, Nov. 7, 2018
Time:9:00 a.m. - 5:00 p.m.
Location: Fairmont Austin (101 Red River St., Austin,TX 78701), rooms TBD
Workshop Overviews
Driving Engagement Throughout the Customer Journey
Acquia Journey: Getting Ready for Journey
In this session you will learn what information your organization needs to successfully implement Acquia Journey and how to obtain it. You will learn how to utilize existing customer journeys and data to create customer journey use cases, identify key triggers and define KPIs.
GeekHive, an Acquia partner and Engage sponsor, will highlight a relevant case study during this session.
Presenters: Bryant Shea
Target audience: Marketers, business leaders, digital strategists or technical architects interested in learning about and how Acquia Journey can improve your overall customer experience.
Acquia Lift: Incorporating Personalization into Your Customer Experience
In this session, you will learn about personalization best practices and how Acquia Lift can support your existing digital marketing program. This interactive workshop will begin by sharing Acquia's perspective on personalization best practices. A brief demonstration of Acquia Lift will occur followed by a discussion on key personalization topics including: staff resourcing, interpreting analytics, and brainstorming personalization opportunities.
Blue Fountain Media, an Acquia partner and Engage sponsor, will highlight a relevant case study during this session.
Presenters: Bryant Shea
Target audience: Marketers, business leaders, digital strategists or technical architects interested in learning about personalization best practices and how Acquia Lift can improve your overall customer experience.
Acquia Lift: Technical Owner Training
This interactive workshop will begin with a brief demo of Acquia Lift, followed by a walkthrough of configuring Lift, instrumenting events, using connectors and APIs, creating slots, and managing structured content. You'll leave the session knowing how to set up Lift and manage content in the application (among many other takeaways).
Presenters: Bryant Shea
Target audience: Developers, technical architects and anyone interested in learning the technical aspects of Lift.
Building for the Future of Digital Experiences
Decoupled Drupal in Action
Decoupled Drupal is the use of Drupal as a content repository and editing tool, while delegating front-end capabilities to an entirely different implementation. A variety of rationales motivate splitting the monolith that is Drupal into separate concerns. For developers, the prospect of using JavaScript frameworks like Angular, Ember, and React in lieu of Twig and PHP can be freeing and accelerate project progress. For marketers, decoupled Drupal is attractive due to its possibilities for new experiences like digital signage, conversational interfaces, and even virtual and augmented reality.
Many bytes have been written about why decoupled Drupal makes sense for Acquia customers, but due to its relative immaturity, content to educate ourselves from a technical perspective can be harder to find or less accessible. Join Preston So, a globally recognized expert on decoupled Drupal, and other Acquia customers for an exciting pre-conference workshop about how to decouple Drupal the right way for a variety of different business goals. In the process, hear from others about their experiences and learn the ins and outs of decoupled Drupal architectures from the big picture to the nitty gritty.
Presenter: Preston So
Target audience: Technical architects, developers, and QA specialists
Continuous Delivery
Using best practices for development is important, especially for enterprise sites that "can't fail." But implementing processes like continuous integration and delivery can be difficult. Acquia's new continuous delivery tools make it easy.
Learn how to increase the reliability, quality, and speed of your development cycles using continuous integration and continuous delivery on Acquia Cloud. Catch bugs before they're merged into your codebase and preview changes before it's time to release!
In this course you will learn how to continuously assure the quality of your Drupal application and streamline your development workflow by running automated tests, validating custom code, and spinning up on-demand development environments automatically.
Presenter: Dane Powell
Target audience: Technical architects, developers, and QA specialists
Transforming Your Organization and Your Technology for Digital Factories
How does a team of less than 10 people successfully build and maintain thousands of sites? Can its success be attributed to products and technology, or is it a result of process and organizational best practices? How do some companies go from taking months to launch a site to weeks? In this session, we will expand on the governance session we held last year. Attendees will learn how organizations, big and small, organize themselves and their technologies to gain maximum efficiency and produce some of the most beautiful sites in the world. We will equip you with best practices, lessons learned from working with a large network of experienced platform owners, and tactical things you can do immediately to ensure that your site production systems and teams are running like a well-oiled machine.
CI&T, as a strategic Acquia partner and Top 5 contributor to the Drupal community, will highlight some of the cases where they have addressed this challenge successfully.
Good for organizations new to governance as well as mature practitioners.
Presenter: Jenni Lee, Mark Sakurada, Jeff Reed
Target audience: Non-technical digital business leaders, technical business leaders welcome too.
Enabling Accessibility
Accessibility Training with certificate of completion
Accessibility, also known as universal design, is the degree to which a product, device, service, or environment is available to as many people as possible on as many devices (e.g. visual browser, screen reader, mobile device, cloud-based voice service) as possible. Although accessibility used to only focus on those with disabilities, as mobile usage and cloud-based voice services are on the rise, accessibility matters to the majority of your platform users.
Given the changes that have come about recently to 508 compliance and the belief that a technical background is a must to understand accessibility, many agencies and organizations are not giving accessibility compliance the attention it deserves and needs.
Join Danielle Sheffler, an accessibility professional with more than 10 years of real world experience and a member of International Association of Accessibility Professionals, for a pre-conference workshop to understand why accessibility matters to your agency or organization, what the differences are between accessibility standards, how to structure content and code to be accessible, and how to test for accessibility. You will come away from this workshop understanding how to incorporate accessibility best practices into your site development and maintenance workflow.
Presenter: Danielle Sheffler
Target audience: Content authors, developers, and QA specialists


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Thank you for visiting the Jackson Plumbing web site. This family owned and operated business has been serving the good people of Fairfield County since 1989.
Todd Jackson, an Army Veteran, is a state licensed, certified, bonded, and fully insured skilled plumber with more than 26 years of experience.
Todd is DOT certified, so he is qualified to install gas lines and piping and conduct gas line pressure testing. Jackson Plumbing specializes in repair services as well as installation of water heaters, faucets, well tanks, water filtering systems, and softeners to name a few. The full list of available services can be found on this web site by clicking on "services".
Todd believes he has been successful because he takes great pride in his work, aims for perfection, and customer satisfaction. With Jackson Plumbing, you will receive quality, courteous, prompt service at a fair and competitive price. Give us a call and experience the difference at 740-653-4109.
Please visit our Facebook page!!


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Master of Arts in Theological Studies
Master of Arts in Theological Studies: a graduate degree designed to equip researchers and those who seek to enter the academic life or pursue higher degrees (Ph.D.,Th.D., etc.). At the moment, the program has three foci:
- Biblical Studies
- Christianity in the Middle East
All courses are taught and evaluated in English. Admission into this program requires a secular bachelor degree, a theological bachelor degree, and a minimum TOEFL score of 500. All tutors are Ph.D. holders.


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- This event has passed.
Senior Citizens
December 13, 2018 @ 10:00 am - 12:00 pm
|Recurring Event (See all)
An event every week that begins at 10:00 am on Thursday, repeating until December 20, 2018
Fellowship Hall. Open to all Senior Citizens in the Franklin/Southampton area. Meet every Thursday at 10am


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After the chaos to get down to Turks & Caicos we did make and now we are back. Vacation was wonderful and much needed. I posted these on my Instagram but I thought I would share here as well.
Above: We made several of these signs for Henry and have not made one for Baby 2, we thought we should up our efforts!
To say we were not excited to come home is an understatement, except we were SO ready to see this guy again.
Now I am back in the office trying to dig out. I hope to be back on here this week, we shall see, in the mean time I hope you have a wonderful week!


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Week 1: Connectivism?
Week 2: Patterns
Week 3: Knowledge
Week 4: Unique?
Week 5: Groups, Networks
Week 6: PLENK
Week 7: Adaptive Systems
Week 8: Power & Authority
Week 9: Openness
Week 10: Net Pedagogy
Week 11: Research & Analytics
Week 12: Changing views
Week 5 - Groups, Networks and Collectives
Dates: February 14 - 21, 2011
- Stephen Downes, Groups Vs Networks: The Class Struggle Continues
- Stephen Downes, That Group Feeling
- Stephen Downes, Groups and Networks (video; here's the image from the video)
- George Siemens, Group and Network (Elluminate presentation)
- Terry Anderson and John Dron, Collectives, Networks and Groups in Social Software for E-Learning
- Stephen Downes, 7 Habits of Highly Connected People
- Wednesday: Live Session: Location: Elluminate Maarten de Laat
Time:8:00 p.m. Moscow; 5:00 p.m. London; 12 noon New York; 9:00 a.m. Los Angeles; midnight Thursday Beijing
- Friday: Live Session: Location: Elluminate Facilitator's discussion.
Time:8:00 p.m. Moscow; 5:00 p.m. London; 12 noon New York; 9:00 a.m. Los Angeles; midnight Saturday Beijing


text: If the Arctic tundra thaws (see the graphic below), climate scientists believe it may represent an irreversible tipping point that sends climate warming out of control. The methane released would take at least 250 years to first be converted into CO2 and then be pulled into the oceans and plant life where it can be removed by fixation. Methane is 21 times more powerful a greenhouse gas than CO2. So, release of one ton of methane is like releasing 21 tons of CO2. In a reference article here: (http://www.wunderground.com/resources/climate/melting_permafrost.asp), it states: "[A]s of 2011, no climate model incorporates the effects of methane released from melting permafrost, suggesting that even the most extreme climate scenarios in the models might not be extreme enough." This article also covers methane hydrates that climate scientists say may, as a result of warming oceans, begin to melt and release the methane trapped in more shallow ocean beds such as the Arctic ocean.


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My styling of this dress was partially inspired by this lovely lady:
|The Carrie Diaries - Episode 11
Have you found any great funky prints lately?
|The Carrie Diaries - Episode 11
This look is just too cute! An outfit full of color and inspired by food is perfection!
Thank you so much Rebecca! My world basically revolves around food and bright colours, so it's an unbeatable combo for me ;)Delete
Oh my word, that dress! I love it so much!! It's just so ridiculously fun!ReplyDelete
I know, isn't it amazing?! I just got around to having enough to money to order it haha, I can't wait for it to arrive, I've got a million more ways to style it too! :) Now I just have to make sure I don't take too much inspiration from the dress itself, or it won't fit me... :PDelete
Ahhh I have this dress and I absolutely love it! It is so fun to style with and I like the things you paired it with- it's given me some fresh ideas ;)
Oh you do?! Isn't it just the best dress, and it's SO wonderful to style, so many colours to match it with!! :)Delete


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1872 Davin DriveGoshen, OH 45122ph: 513 722-2400fax: 513 email@example.com
Please contact us anytime with questions. Our phone number is 513 722-2400 and our e-mail is firstname.lastname@example.com
Maryellen Soergel
We are located in Goshen Township in Clermont County, 10 minutes from Milford or Loveland, but are also convenient to several Hamilton, Warren, Clinton and Brown County locations such as Indian Hill, Terrace Park, Mainville, Morrow, Blanchester, Newtonsville and Fayetteville.
Copyright 2012 Milford Goshen Kennel, Inc.. All rights reserved.
Web Hosting by Yahoo!


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Contact lens insertion and removal doesn't need to be a big production. With practice, you will find that this process becomes second nature!
The following procedure will assure correct preparation of your contact lens for insertion
Begin by washing your hands with soap and warm water, avoiding soap that contains fragrance or oils. These substances can cause eye irritation by coming in contact with your lens. a lint free towel should be used to dry your hands.
To avoid accidental loss of lens, always close the sink drain prior to lens preparation. It's important to develop the habit of inserting your lens in the same order eery time to avoid mixups. Carefully remove the lens from its storage case or lens package. Then set the lens into the palm of your non-inserting hand, and rinse it with a solution recommended by your eye care professional. This process should remove all traces of debris.
Next, place the lens on the dry tip of your index finger. Examine the lens to assure it is moist, clean, clean, and free of nicks and tears. If the lens appears damaged, do not use it. You are now ready to apply the contact lens.


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Have you ever dreaded the mindless routine of commuting to work, sitting at your desk and wanting to be somewhere else, and watching the clock anxiously until it was time to go home?
Just to do it all over again the next day?
If you have ever felt numb at work, it means you've lost that spark of starting a new job, excited about the potential at your fingertips. How do you get back that feeling of feeling alive and completely engaged at work?
By being creative. Literally.
Creativity is the ability to express your authentic self in a meaningful way, one where you're not hindered by strictly following the rules. It's also a great way to feel more present in the workplace.
The ability to be creative at work gauges whether you are authentic at work or not. You just need to devote time to cultivating that creativity.
Here are three ways to wake up your creativity at work:
1. If you genuinely believe in something, speak up
Is there something you're passionate about at work, something that energizes you? That makes you say, "This is why I wanted to work here"? The big question is: How can you get more of that in your daily job? Be present and pay attention to when this happens. One way to be creative is to take whatever it is that makes you feel like you belong at your job, and attract more of it to your daily tasks. This might mean a conversation with your boss, to defining a role that highlights these strengths. Express yourself and make your interests known.
2. Don't fear failure
At work, it's easy to fear failure when you think of everything at stake— from humiliation in front of coworkers, judgement from your boss, and the possibility of losing financial security if you fail. But work, which takes up a good amount of our lives, is where you should be encouraged and rewarded for creativity. Innovation comes from taking risks. Real life comes from taking risks.
3. Believe that you belong at the table
Do you feel like you actually fit in to your work culture? Like any commitment you make, it should feel right or it's not even worth investing in your time. Yeah, it sounds like a luxury to find a place you belong in, but the alternative is to spend your days feeling like you never truly belong. Eight hours a day, 40 hours a week is lot of time that you're spending there, so you should feel like you can be yourself. Just like finding "the one" in a romantic relationship, you have a choice to decide what company you commit yourself to. If you and your current company don't have the same things in mind for your career, there are a million of other fish in the sea.
In order to feel more alive at work again, you have to take back ownership of your career, and foster your creativity. Instead of being reactive, be proactive about crafting the role you want. Find those reasons that make you want to stay, and really analyze if this place is somewhere you want to be for a long while. Take ownership of your career path, and if you feel like you're stuck in a rut, it's time to come alive again.
To see this article as it appears on the Delivering Happiness website, please click here.


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The new Judd Apatow comedy "This Is 40," which hits theaters on Friday, December 21 (aka the day of the Mayan apocalypse), stars Paul Rudd and Leslie Mann as a married couple dealing with the fact that they have turned 40 and their lives aren't what they expected. Hey, join the club, right?
But while their expectations may be out of whack, there's nothing wrong with having high expectations for things born in 1972. That's because 40 years ago, Hollywood put out a crop of new movies that haven't just gone on to become classics — on a fundamental level, they've changed the way people think of cinema.
So to celebrate their 40th birthday, here's a look back at some of the most important and influential films that were born in 1972.
The Scoop: Adapted from Mario Puzo's popular novel about a family of mobsters, "The Godfather" was expected to do pretty well at the box office. It was a real leap of faith to entrust it to a mostly unknown director (Francis Ford Coppola) and an even more unknown leading man (Al Pacino). As it turns out, that roll of the dice ended up paying off some very long odds.
The Legacy: It hardly needs to be said, but 'The Godfather" became an instant classic, establishing Coppola and Pacino as instant A-list talents and thereby indirectly leading to dozens of great films. Routinely cited by fans and critics as the greatest film of all time, "The Godfather" set a new bar for cinematic excellence that has rarely been met.
The Scoop: Gene Hackman, Ernest Borgnine and Shelley Winters were just a few of the kinda biggish names filling the cast of this ensemble piece about an ocean liner that gets capsized by a tsunami. The result is basically "2012" crossed with "Titanic" by way of "The Day After Tomorrow."
The Legacy: One of the reasons "The Poseidon Adventure" calls to mind those films is that "The Poseidon Adventure" basically created the template for both the disaster epic and the modern effects blockbuster. It put action and in-your-face theatrics ahead of, well, everything else, and for better or worse, people like Michael Bay were paying very close attention. You're welcome?
The Scoop: Liza Minnelli stars in this Bob Fosse-directed musical about a cabaret singer in pre-World War II Germany who gets caught between two men during the rise of the Nazi Party.
The Legacy: At this point, it's almost been forgotten that despite being up against "The Godfather," "Cabaret" still won eight Oscars, including Best Director for Fosse, who beat out Francis Ford Coppola. That would be enough of a legacy for most films, but "Cabaret" also cemented Minnelli's status as a counter-culture icon, setting her on the path to become the entertainment icon she is today.
The Scoop: Considering it's one of the most famous films of the '70s, you're probably all familiar with the basic story of "Deliverance," but here goes: Burt Reynolds and Ned Beatty play two members of a group of city slickers who go on a camping trip, only to run into some inbred weirdos who do a little bit more than rough them up.
The Legacy: "Deliverance" has left a pretty big footprint on the pop culture landscape. Reynolds, for instance, parlayed his success in the film into becoming the biggest movie star of the '70s. The basic elements of the film, from the hillbilly antagonists to the revenge fantasy action sequences, have become standard Hollywood fare. Most of all, of course, there is the infectious song "Dueling Banjos" and the timeless catchphrase "squeal like a pig." We're shuddering just thinking about it.
'Everything You Always Wanted to Know About Sex (But Were Afraid to Ask)'
The Scoop: As we'll see, 1972 was a big year for sex in the movies, and Woody Allen was at the forefront of this movement thanks to his high profile adaptation of the popular self-help guide of the same name. Where the book took sex more or less seriously, Allen went very much for the less seriously side of things.
The Legacy: Though the film was important in terms of its cultural impact, it's probably more notable for its effect on Allen's career. Though he had some previous hits on his resume, they were more traditionally structured comedies. "Everything You Always Wanted to Know About Sex (But Were Afraid to Ask)" allowed him to experiment and stretch himself. As a result, in many ways, it's the first of his films clearly recognizable as a Woody Allen movie.
'Fritz the Cat'
The Scoop: Based on the underground comics by Robert Crumb, "Fritz the Cat" was a satirical X-rated animated film following the adventures of a sexually active anthropomorphic cat exploring what passed for culture in early '70s New York.
The Legacy: Both Crumb and animator Ralph Bakshi rose to instant fame as the result of the movie's unprecedented success. 40 years later, "Fritz the Cat" remains the most successful independently made animated film, with over $190 million worldwide at the box office. It also was a landmark in animation for its content, which obliterated forever the idea of animation being for kids only and paved the way for the more serious and adult animated films that have followed in the years since.
'Deep Throat'
The Scoop: As the title implies, this is a porno. Linda Lovelace stars as, well, a lady in a porno.
The Legacy: "Deep Throat" was basically the first porno to actually have a plot and developed characters as opposed to, you know, people just engaging in sex on film. The film became a sensation, launching a whole new style of pornographic film and also legitimizing pornos to a degree, as the (relatively) more sophisticated take brought with it a level of mainstream acceptance. The late Lovelace later famously denounced the film, but "Deep Throat" still remains a milestone in the evolution of America's sexual mores.


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Bona Restó
Our chef, Juan Chañi, has designed a menú that joins international dishes with the typical food of Argentina so you will be able to find different options such as vegetarian dishes, low fat dishes and gluten free dishes that you can enjoy at any time of the day.
We want you to be able to enjoy a complete and pleasurable experinece. The environment, the flavors, the smells and the textures get together so you can enjoy every moment and every of your meals at Bona become a unique and pleasurable time.


text: Corporate Partners 1199C Aetna Albert Einstein Healthcare Network Allied Universal American Heritage Federal Credit Union American Paradigm Schools AmeriHealth Caritas Aqua America, Inc. Beneficial Bank Benesyst Brown's Super Stores Canon The Carney Group CHOP CIGNA City of Philadelphia Comcast Community College of Philadelphia Congreso Corizon Health Corporate Call Center Delaware County Community College Easterseals ECFMG EdAssist GCC IBT District Council 9 Greater Philadelphia Chamber of Commerce Harrah's Chester Health Partners Plans hibu Independence Blue Cross IREM JEVS Magee Rehab Merakey MHM Penn Medicine PGW Philadelphia Education Fund Philadelphia Housing Authority Philadelphia Works PHMC PPA Quest Diagnostics Santander School District of Philadelphia SEPTA St. Christopher's Hospital for Children St. Mary Medical Center Subaru of America, Inc. UnitedHealth Group UPS Wawa Year Up USPS TD Bank Employer Relations Academic Partners Year Up Alternative Credit Providers Lumerit Partnership Study.com and Peirce College Looking for More Peirce Information? Request Information School District of Philadelphia School District of Philadelphia Corporate Partnership Peirce College and School District of Philadelphia Corporate Partnership You probably expect college to be a little different for you as a working adult learner than it is for traditional-age students. And you should, too. Your needs are different. It's been a long time since you've been in a classroom, taking notes and tests. In the meantime, you've gotten a job, picked up more than a few responsibilities and maybe even started a family. So how is higher education going to work for you?Well, if you choose Peirce College, you'll be choosing a school that has focused on the unique needs of adult education for more than 150 years. Since its founding in 1865, Peirce has offered the sort of market-relevant programs that adult learners need to help them advance their careers. You need the type of practical skills and knowledge that employers look for in job candidates, and you'll get it at Peirce. What's more, you'll be able to take flexible, accelerated courses to help you balance school with your work and life. Courses start every two months at Peirce and are available online or on campus. If you need to, you can even switch between online and on-campus learning every week – the choice is yours.Corporate Partnership Tuition DiscountWorried about the cost? Don't be! Attending school at Peirce is more affordable for employees of the School District of Philadelphia. That's because District employees and their spouses and dependents can take advantage of the tuition discount made possible through our corporate partnership program.To receive your Peirce College corporate discount, simply complete a Peirce College application and select your employer when asked how you heard about Peirce. A Peirce admissions representative will then be in touch to guide you through the next steps. To see a full list of benefits Peirce offers through our corporate partnership with School District of Philadelphia, click here. About School District of PhiladelphiaThe country's eighth-largest school district, School District of Philadelphia, is located in the historic and culturally rich City of Brotherly Love. Philadelphia's ethnically and racially diverse citizens are committed to quality education. The District's mission is to deliver an exemplary public school education to every child in Philadelphia and ensure each one graduates from high school prepared to succeed on the road ahead. Contact an Admissions Rep Request More Information


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Vol. LXII, No. 45
Wednesday, November 5, 2008
For more movie summaries, see Kam's Kapsules.
HOW DID YOU MANAGE TO BECOME FOUR INCHES SHORTER THAN YOU WERE BEFORE YOU DISAPPEARED?: Christine (Angelina Jolie, right), who, despite her protestations to the contrary, was pressured into accepting that the child in the picture (Devon Conti) was her missing son Walter (Gattlin Griffith, not shown). However, every test that Christine subsequently applied to the imposter only proved to her that she was correct in her belief that this child is not her real son.
When a movie opens with a message stating that what youre about to see is A True Story you would expect to see an historical drama far more credible than the patently absurd Changeling. Perhaps if director Clint Eastwood had qualified the claim with words like Based upon or Inspired by, the pictures preposterous premise might have been a lot easier to accept.
The movie opens on March 9, 1928 when we are introduced to Christine Collins (Angelina Jolie), a single mother raising her nine-year-old son (Gattlin Griffith) in Los Angeles. As part of her job with the phone company, Christine moves around the floor of her workplace on roller skates as she supervises a bank of operators.
The plot thickens when she agrees to fill in for a co-worker on a Saturday, and has to leave her son Walter home alone. When she returns after work, the boy has vanished without a clue, so she calls the police and files a missing persons report.
Several months later the cops tell her that they have found Walter alive and well in DeKalb County, Illinois and that hes coming back to Los Angeles on a train. However, Christine cant believe her eyes when she sees that the child who disembarks from the train is not her missing child, but is an impostor (Devon Conti), whos four inches shorter than her son was when he disappeared.
This is where the movie starts to make no sense. Instead of accepting the mothers assertion that this child was not hers, were supposed to believe that the Los Angeles Police Department pressured Christine into accepting a perfect stranger as her missing son. Apparently the department was more concerned with getting positive press coverage for cracking the case than with reality.
Doesnt that sound inhuman? And how long could a young impersonator keep up such a charade, even if he had wanted to? Wouldnt the fraud have been exposed the first time Walter went out to play with his friends, visited relatives, greeted neighbors, or returned to school and was unrecognized by his teachers or classmates? Something simply doesnt add up here.
Be that as it may, the authorities reaction to Christines attempts to provide them with physical evidence that proves that the child is an imposter, is to have her committed to a mental institution. They make no attempt to ascertain the accuracy of such a readily verifiable claim as to whether or not her son was circumcised. Additionally, a support group led by Reverend Gustav Briegleb (John Malkovich), a corruption fighting crusader, apparently had no impact on the authorities either.
However, when a mass grave with a score of bodies was uncovered on the ranch of a serial killer (Jason Butler Hamer), the powers-that-be started to believe that Christine might not be psychotic after all.
After she is released from the mental institution, she enlisted the pro bono assistance of an attorney (Geoffrey Pierson), and the dominos started to fall. In the wake of a publicized review board hearing, the careers of the Mayor (Reed Birney), Chief of Police (Colm Feore), and a police captain (Jeffrey Donovan) were destroyed.
Regrettably, neither the painstakingly recreated period backdrops nor the casts inspired performances outweigh Changelings fatal flaw which rests upon a fanciful conceit, pretensions to the truth notwithstanding. A crime saga strictly for the very gullible.
Fair (1 star). Rated R for profanity, violence, and disturbing content. Running time: 141 minutes. Studio: Universal Pictures.
For more movie summaries, see Kam's Kapsules.
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Comcast customer serviceA funny (funny for us not for the parts involved) video showing how a Comcast technician was trying to replace a cable modem. Actually before starting the actual repair he had a few deep thoughts, deeep thoughts. Watch the A Comcast Technician Sleeping on my Couch Youtube movie below.
The story is this, the comcast technician came over to fix this guy's modem and after an hour on the phone with Comcast he fell asleep. It would be pitty not to mention the thank you notes that the customer posted. Thank you for:
- two broken routers
- four hour appointment blocks
- weeklong internet outages
- long hold times
- high prices
- three missed appointments
- promising to call back and then not calling


text: National Theatre play Great Britain to transfer to Haymarket Posted on Jul 2, 2014 | By London Theatre Direct Following a rapturous reception at its National Theatre press night, new play Great Britain, penned by Richard Bean, has already been confirmed for a Theatre Royal Haymarket transfer after just one official performance. The satirical show currently stars Billie Piper in the lead role, who will possibly join the new production. In the National Theatre production of Great Britain, Piper stars as determined newpaper editor Paige Britain, who will stop at nothing to keep her 'red top' newspaper at the top of the heap. Echoing recent real-life scandals, she learns about phone hacking and subsequently sets about blackmailing government officials and the police - in fact anyone with power - in order to solidify her position. The Great Britain production has been widely praised not only for its performances but also for its biting satire and razor-sharp commentary on today's society. The show is set to open at the Theatre Royal Haymarket on 10 September, with tickets on sale from Friday 4 July. Although none of the cast for the new venue has yet been announced, a continuation of many of the current cast seems likely. In the current production at the National Theatre, Piper is joined, amongst others, by Robert Glenister, Harriet Thorpe, Dermot Crowley, Jo Dockery and Oliver Chris. The Telegraph describes Piper's Paige Britain as "a sultry, stiletto-stamping schemer who might as well sprout devil's horns", whilst the London Evening Standard says she's "a devious flirt, a smug and skilful operator with an infallible eye for an outrageous story. And as she masterminds a campaign of phone-hacking, proving at once odious and irresistible, Piper is thrillingly persuasive" and also deems director Nicholas Hytner's production "pacy and busy" Great Britain tickets, on sale this Friday for the Theatre Royal Haymarket production are likely to sell fast, particularly once casting is confirmed. News


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171 10th Street
2nd Floor
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Phone: 412-393-0200
Fax: 412-393-7104
Office hours 8:00am - 5:00pm
Email: email@example.com
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A copy of the SEA Right-to-Know Law Request Policy can be found by
clicking on this link: SEA Right-to-Know Policy. The Standard Right-to-Know Request Form can be found by clicking on this link: Right-to-Know Request Form. Right-to-Know Law Requests should be sent to the SEA's Open Records Officer at:
firstname.lastname@example.com or sent in writing to 171 10th Street, 2nd Floor, Pittsburgh, PA 15222.
Accessibility Information
For questions concerning accessibility at SEA or Stadium Authority facilities, please contact the Facilities Director at 412-393-0200.
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Friday, July 30, 2010
I had this old chair that I purchased around 1995 that was desperate for a re-do.It started out in my bedroom at home as a little escape for reading. Then it got pushed out of there for a exercise bike and relegated to the basement to withstand some character building abuse from the kiddos.
So in mercy, I drug it down the shore and stuffed into my tiny serene bedroom, where it hardly got any use till recently, when we had the back deck renovated and made it into a sunroom right off my bedroom which now houses all kinds of comfy furniture for taking in the view.
So here is the before.... hardly fitting in with the beach vibe we were going for....right?
I really wanted to find a fabric similar to the one in this Coastal Living magazine picture below.
With a bit of a nautical vibe. (This was in my vision file since 2002)
My vision file is just a file of stuff I love.
And I love the look of this chair right down to the cozy blanket on the ottoman!
Inspiration Love
So I finally found the fabric I would use!
But I am such a procrastinator some times.
This was one of those times. I'd made a slipcover once before for my sofa and I sewed for 12 hours straight, just stopping for nourishment! It's not something I am great at and didn't really look forward to.
Finally though this job was going to get done!
And here is the end result:
Much more beachy
It fits in the room much better now in it's new skin. And it's still one of my most comfy little chairs! This nautical fabric is now available in my online fabric store, FreshCutFabrics.com It is called Millbrook stripe by Waverly.
Thanks foe stopping by!


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Feb. 28, 2013
COLUMBUS, Ohio – The No. 18 Ohio State women's gymnastics team hits the road to take on Illinois State at 5 p.m. ET Sunday in Normal, Ill.
Fans can find links to a live video stream and live stats at OhioStateBuckeyes.com or follow on Twitter at Twitter.com/OhioState_WGYM.
Ohio State posted a season-best 196.300 to top Illinois last Saturday in St. John Arena. Sarah Miller either won or tied for the event title in all three events she competed in while Melanie Shaffer tied her career-best 39.350 to take the all-around title. As a team, the Buckeyes posted season bests on bars and floor exercise while tying a season high on beam.
Ohio State is currently ranked 18th nationally in the GymInfo Top 25. Six other Big Ten teams are ranked including Michigan (No. 3), Nebraska (No. 10), Minnesota (No. 14), Illinois (No. 19), Penn State (No. 22) and Iowa (No. 24).
As a team, the Buckeyes are 14th nationally on balance beam (48.910 RQS), 18th on floor exercise (48.990), 21st on uneven bars (48.925) and tied for 22nd on vault (48.970).
Individually, Sarah Miller is tied for eighth nationally on beam, 11th on vault and tied for 18th on floor exercise.
Sarah Miller was named Big Ten Event Specialist of the Week, the conference office announced Feb. 25. The award marks the 13th career Big Ten weekly honor and fifth of the season for the Collegeville, Pa., native.
Miller either won or tied for the event title in all three events she competed in as the Buckeyes posted a season-best 196.300 in a dual meet win over Illinois Feb. 23. She tied a career best 9.950 to take the vault title, tallied a 9.925 to win beam and tied for first with a 9.875 on floor exercise.
Ohio State was picked third in the Big Ten Preseason Coaches' Poll, the conference office announced Dec. 12. In addition, juniors Sarah Miller and Melanie Shaffer have been named Gymnasts to Watch in the conference.
Nebraska was picked first followed by Michigan, Ohio State, Penn State and Minnesota. Illinois, Iowa and Michigan State rounded out the poll.
Senior Colleen Dean and juniors Sarah Miller and Alex DeLuca have been named captains of the 2013 Buckeyes, head coach Carey Fagan announced.
Miller earned second team All-America honors on balance beam and floor exercise last season while Dean garnered second team All-America honors on floor exercise. The duo became the seventh and eighth All-Americans in Ohio State women's gymnastics history. It is the first time the Buckeyes have had multiple All-Americans in the same season. DeLuca is a two-year letterwinnner who posted career bests of 9.850 on bars and 9.875 on floor exercise a year ago.
The Buckeyes host Bridgeport at 4 p.m. March 9 on Senior Day in Columbus.


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This is the 3rd week of school and so far, my beginning orchestra has learned to hold their instruments and bows (I still reinforce proper position every day). They can also pluck basic open-string back-up parts to a fiddle tune called Sourwood Mountian and they have learned how their instruments are set up so they can find any note on any string by going through the music alphabet on each string. (I taught this using a basic fingering chart). After that, I had students practice placing fingers up and down the D and A ladder and plucking/bowing using tukka tukka stop stop. We then learned the D scale.
I have not done anything in our method book, yet. I like to have students gain confidence AWAY from music for awhile so they can focus on proper position, finger placement, and intonation. When we do start our method book, we will be able to cruise through the first several pages very quickly because students will already have a solid foundation.
Tomorrow, I am going to pass out the music to ARKANSAS TRAVELER. There are two levels in my beginning class and my advanced-beginners need a challenge. They will learn the melody line while I teach the back-up parts to my true-beginners. Since they are not reading music yet, they will use a special back-up part that I prepared with fingering and note names. I like to have them learn without written notation at first so students quickly learn and place fingering on the D string. After they learn the back-up part, they will know where all of the notes are on the D string and when we are reading music, it will be easier for them to make the connection with notes and finger placement.
My true-beginners will be memorizing the notes on the D string in the next 2 weeks and once they can read those notes, I will have students read the actual back-up sheet music with a new rhythm.
You can purchase a copy of my Arkansas Traveler arrangement HERE and may print off as many parts as needed each year....a great value! Included in the download is 23 pages...included a score, parts for each instrument, and a pre-notereading simplified back-up part for each instrument.


text: While we at Index Funds Advisors, Inc. do not dismiss the bleak scenario envisioned by the authors of books such as Aftershock or The Day after the Dollar Crashes as completely implausible, there are a number of problems with books of this doomsday genre that deserve consideration: Economic forecasting is a fool's errand at best. We know that the "experts" do no better than we would expect from chance alone. The reason for this is that the economy is infinitely complex and subject to myriads of unknown future events. There simply is no model that can adequately capture it, and it is unlikely we will see one anytime soon. It is important to understand that the market itself has some economic forecasts embedded in financial instruments such as interest rate futures contracts and in combinations of securities such as the yield difference between nominal and inflation-protected Treasury bonds. None of these market-based forecasts (where real money is at stake) currently indicate future high inflation. Furthermore, the currency futures and forwards markets do not predict a future large devaluation of the dollar. For most investors, it is probably not a good idea to bet against any of these markets. Even when an economic forecast is accurate (or perhaps lucky), it tells you little if anything about how you should position yourself. We have several examples of people (like Peter Schiff) who correctly called the real estate bubble yet still lost money because their predictions about which asset classes would thrive were simply wrong. Even if the predictor is right about what positions to take, getting the right timing on these positions is critical. For example, we know that those hedge fund managers who arrived too early to the long position on the credit default swap trade were unable to hold their positions in the face of mounting losses. The market stayed irrational longer than they could stay solvent. A more recent example is Bill Gross who predicted at the beginning of 2011 that the Treasury bond bubble was ready to pop. The bearish bets that he made against long-term T-bonds turned against him and he was forced to do a "mea culpa" after falling 3.7% short of his benchmark. Our point is that if Bill Gross who has access to a staff of PhD economists that could put most university faculties to shame couldn't get the timing right, then what possible hope do you or the authors of the doomsday books have? Perhaps someday Bill Gross's bet will work beautifully and whoever does get the timing right will be the subject of all manner of media adulation, but Bill Gross's experience proves to our satisfaction that luck will be the more likely explanation than skill. Most of these books are thinly veiled attempts to get you to purchase additional services offered by the authors (e.g., subscription newsletters, expert consulting by the hour, etc.). Getting down to the question of the predictions made in these books, the central theme is that the US government has taken on too much debt and has vastly increased the money supply (quantitative easing) in an effort to keep the financial markets afloat, both of which will eventually lead to an economic calamity characterized by high inflation and a collapse of the dollar. We certainly will not say that any of this is untrue, and we do agree that the actions of the Fed and our political leadership have increased the probability of this bleak scenario coming true, but it does not have to unfold the way the doomsday purveyors predict. The Fed does have the ability to soak up the extra liquidity it has created by selling the bonds it has purchased. The timing of course, is critical. Regarding the massive increase in public debt, yes this is a terribly difficult problem to solve because debt never goes away. However, we like to think of Winston Churchill characterizing America as a country that will do the right thing when all other options have been exhausted. The only way it will be solved is a combination of economic growth and entitlement reform (Medicare, Medicaid, Social Security, government pensions, etc). Even if we taxed millionaires and billionaires at 100% of their wealth, it would not raise enough revenue to solve the underlying spending problem. It is important to bear in mind that there is no feasible way for the market to be surprised by the debt. Everybody knows about it. One question worth asking is whether the cost of capital of publicly traded companies (which is what drives the return on equities) is truly dependent on the amount of government debt outstanding. Historically, there is no clear-cut relationship; there have been times when the market has done quite well when there was a vast increase in the public debt (e.g., World War II). Likewise, there have been times when the market did poorly as the debt-to-GDP ratio was reduced (e.g., the late 1940's). In closing, we would caution investors against making any investment decisions based on what they read in any of these books regardless of the accuracy of the authors' past predictions. Step 4Time PickersGurus Are Inaccurate Too OftenMarket Gurus Previous Article Next Article All Articles About Index Fund Advisors Index Fund Advisors, Inc. (IFA) is a fee-only advisory and wealth management firm that provides risk-appropriate, returns-optimized, globally-diversified and tax-managed investment strategies with a fiduciary standard of care. Founded in 1999, IFA is a Registered Investment Adviser with the U.S. Securities and Exchange Commission that provides investment advice to individuals, trusts, corporations, non-profits, and public and private institutions. Based in Irvine, California, IFA manages individual and institutional accounts, including IRA, 401(k), 403(b), profit sharing, pensions, endowments and all other investment accounts. IFA also facilitates IRA rollovers from 401(k)s and 403(b)s. To find out more about the value of IFA click here. To determine your risk capacity, take the Risk Capacity Survey.


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I'm running a little slow today. HeroesCon ended at 6pm yesterday and Joe Pekar and I were on the road by 6:30. We drove a while and then picked up a quick bite to eat and loaded up on Red Bull and Mtn. Dew. Normally I like to drive as non-stop as possible, but there was a need to keep getting more caffeine as the long drive continued. It took 8.5 hours to get Joe home and then another 2 hours of driving for me to get home at 5am. I managed to sleep for a couple of hours and then I had to get started on work. Whew.
But who cares about that??? Let's look at some more sketches!
First up is a Cheshire for Shane. I have to admit that it was Diary of Night writer Will Allred's idea for me to pull out the red acrylic paint for the blood. Good Will Calling. And thanks Shane, glad you liked it.
A thank you to Ben for commissioning Desire, of The Endless. Again with the red paint.
And a Wonder Woman for Leigh rounds out this batch. Thanks Leigh!
As always the show was a lot of fun. Joe Pekar was set up to my left and Big John Beatty and Craig Zablo were to my right. No one was going to mess with our tables with this crew around. :)
The area behind my table became a rest stop for a bunch of nice folks. Of course Will Allred was there, sharing the table. But then we would have Will's lovely wife Stacy and their boys stop by from time to time. Patrick would sit with me for a while and shoot the breeze. Little John and his lovely wife Patricia would hang out from time to time. Patricia and I would talk about old Southern California places we both knew and grew up near. Pat Sun, Super Photog would be around there too when he wasn't documenting the convention. Royce (Yes, Little John, there is a Royce Thrower), his brother Eric dropped by from time to time along with "couch crasher" Anthony. Royce had to stop by quite a bit just to see what version of his sketch I was on. Tracy stopped by a couple of times to visit but his son Logan didn't make it this year. Always great to see Tracy and I hope Logan makes it next year. Erica dropped by to pick up Catman and chat a bit. Though she only dropped by once, it was great to see her.
One of the really cool things this last weekend was my best friend Tom Fleming came to HeroesCon for the first time. This is not Tom Fleming, the artist, but Tom Fleming, comic art fan/dealer and owner of www.fanfare-se.com. He brought along his friend John. I've met John before and it was great to hang out with him and Tom at the show and in the evenings. Tom brought along a stack of original art from the 1970s DC romance comics and the three of us, along with Patrick, tried to identify the artists. There were no credits on them or in any on-line data base. Almost like a game show.
I know I am forgetting some folks and I apologize. The brain is a terrible thing and mine is gone right now. As soon as Will finishes the drive home to Arkansas and emails me the scans he did of several more sketches, I will post them. So lets all wish Will and his family a safe trip home. :)
So, more tomorrow.
One Important Note: I did a sketch for Chris, whose last name I did not get. I need him to contact me. The sketch I did for him was of Marvel's Valkyrie. I'm hoping he visits this blog but if not, if anyone knows him, ask him to email me. Thanks!
This is Post #977


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Job Description
Managing a team of design engineers the Senior Avionic Design Engineer will have responsibility for the design and certification of avionic systems and installations for Military and Civil customers. You will build strong and concise relationships with Product Development and Business teams to support the customer.
As a Senior Avionic Design Engineer, your main responsibilities will be/include:
*Review and understand customer modification requirements, to produce avionic system architectures, scheme designs and installation drawings
*Conduct Engineering reviews such as PDR and CDR, both internally and with the external customer
*Managing a small team of design engineers
*Production and checking of drawings in accordance with business procedures
*Liaison with maintenance and production teams to resolve queries encountered during the installation of avionic systems
*Support the company's Certification databases
*Support business development activities
Successful candidates will have/be:
*Degree qualification in Aerospace or Electrical Engineering (or equivalent)
*Significant experience in the Rotorcraft design field (either military or civil) and avionic modifications in the fixed wing domain
*Applicable aerospace engineering experience in test and production environments
*Proven experience of the Inventor or CATIA CAD systems
*Aircraft avionic and capability modification design in the Rotorcraft domain
*Use of MoD and Civil technical standards, certification methods and specifications
*Understanding, recording and analysing avionic engineering data and requirements to determine the most appropriate solution
*Technical experience with Rotorcraft in the production/maintenance environment
*Holder of EASA for 4 approval and/or DAOS nominated for avionics
*Excellent communication skills , with the ability to liaise with a variety of departments
*Task schedule management to meet customer needs
*Membership of RAeS of IMechE ideally
Senior Avionics Design Engineer
Location- Gosport
Salary- DOE + competitive benefits
Key Words: Avionics, Aerospace, Aeronautical, Rotary Wing, Helicopter, Rotorcraft, Aircraft, Civil, Military, Electrical, Systems, Design, Calculations, EASA, Def Stan, CATIA, Autodesk, CAD, PDR, CDR
Due to the nature of work undertaken at our client's site, incumbents of these positions are required to meet special nationality rules and therefore these vacancies are only open to sole British Citizens. Applicants who meet this criteria will also be required to undergo security clearance vetting, if not already security cleared to a minimum SC level.
Electus Recruitment Solutions provides specialist engineering and technical recruitment solutions to a number of high technology industries. We thank you for your interest in this vacancy. If you don't hear from us within 7 working days please presume your application has been unsuccessful on this occasion. You are of course free to resubmit your CV/details in the future and we shall assess your suitability at that time. This role is a permanent position.
Electus Recruitment Ltd is acting as an Employment Agency in relation to this vacancy.


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Yesterday we hiked the Navajo Trail and Queen's Garden combination. It was one of the most beautiful hikes we have ever done and we plan on doing it again soon! Â Unfortunately the battery on my good camera was dead (Ugh!) and so Da's 'point and shoot' had to do!
On the way…Panquitch, Utah….a trip back in time!
And a tunnel in Red Canyon…
When we arrived at Bryce Canyon, the shuttle driver asked Mouse to honk
the horn to announce that the shuttle was leaving.
She was more than happy to help out!
Our first view of Bryce Canyon from Inspiration Point.
Rather than taking the shuttle again from Inspiration Point to Sunset Point,
we walked the half mile on Rim Trail.
At Sunset Point we took the trail head to Navajo Loop Trail.
(Note the zig zag path below.)
We descended 580 feet down what they call Wall Street.
These trees are at the bottom, along with a sign warning those entering Wall Street
to be aware that this is the most dangerous portion of Bryce Canyon because of rock falls.
Nice to know we had already finished it!
And this is the last shot I got before the battery died on the camera. Â ;o(
At this point the trail starts zig zagging back and forth again, climbing 580 ft. to the rim.
We will be back for more and next time I will bring my good camera.


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For 16 years now, the Bronx Academy of Arts & Dance (BAAD!) has celebrated Women's History Month with its annual BAAD! Ass Women Festival.
Arthur Aviles, the artistic director at BAAD!, said the working title of the festival was originally "BAAD! Girls."
"But then the women involved were saying, 'I ain't no girl! I'm a badass woman,'" he said. "So it became the BAAD! Ass Women Festival."
This year, the festival features dance performances, an art exhibit, poetry, cabaret, talks and more. Choreographer and actress Noele Phillips has been working with the festival for eight years.
"I love working with the BAAD! Ass Women Festival, because I'm asked to come in during Women's History Month and tell my stories," she said.
"The festival celebrates women from different walks of life, from Audre Lorde to Michelle Obama, and the different things women go through as a whole," she continued. "As a collective, women still go through similar things."
Her own work, a solo dance piece performed on Saturday, told the story of a woman processing her breakup.
"Every woman has had that experience, regardless of whether she is gay or straight, or their race or class," she said.
Ms. Phillips said she is especially looking forward to the conversation with Gloria I. Joseph, the last partner of famous black feminist and activist Audre Lorde, who died in 1992. That talk will take place on Tuesday, March 22.
"When you come to see events at BAAD!, you learn more about what's going on in an area other than just your own section of the Bronx," she said. "You gain some knowledge when you come to BAAD!"
Mr. Aviles said that desire to inform was the driving force behind the festival's art exhibit, which features portraits of Bronx-based artists of color who are transgender and out.
"A lot of us don't know who they are, so we want to give a space for that," he explained.
Mr. Aviles acknowledged it is a little strange that the festival is run by two men: BAAD! Executive Director Charles Rice-Gonzalez and himself. At the beginning, Mr. Aviles thought he should step aside, but he said in fact, the women involved in the project encouraged him to remain in charge.
"The women around us were keeping us to task about how it is we are versus who it is they are," he said. "I did think about leaving, but it's about coming together."
"The whole program is so good, it's hard for me to pinpoint something," he said. "That's why we like to say, come on over to BAAD!, where it's all good."
The BAAD! Ass Women Festival runs through Saturday, March 26. All performances take place at BAAD!, located at 2474 Westchester Ave. Go to www.baadbronx.org for a list of performances and to buy tickets in advance. Members of the public can set up a time to view the exhibit by calling 718-918-2110.


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text:
I think we all have those records that transport us out of our mundane lives and take us away somewhere magical.
When I listen to Kyuss, I'm floating on a psychedelic sparkly cloud 10 miles up above a desert canyon. I am not on my hands and knees scrubbing the skirting boards, rigid with backache and praying this baby will turn into a slightly less awkward position for birth.
This week I have been mostly hoping that with the gut-shaking power of rumbling bass and downtuned guitars, the baby will flipflop around into prime position, thereby saving me hours of googling back-to-back babies and sobbing with the fear of being in agonising back labour for a week. On the up-side, at least I know both of my TENS machines are working now. And there are many spare batteries. Many, many spare batteries.
Back to the music. I think when you're a youngster, or maybe during a particularly thoughtful period of your life, you have those albums or songs that let you vanish inside yourself. It definitely gets harder to lose yourself in music as you grow up, but the second you put on an old CD or song – BOOM. You're floating in space again, suspended above the canyon, or getting whatever it is that feeling is that transports you. I think this is what inspires legions of embarrassing uncles and aunts to leap onto the dancefloor and start fist-pumping at weddings the second a song from their youth comes on. The opening notes in that song push those magic brain receptors and they're young again, and they can get away with dancing like that (even if they really can't).
These magic switches are also helpfully effective at distracting you from pain. Need to push out another impossible 2 kilometres in your half marathon? Put on your favourite songs, get the endorphin release, take your mind somewhere away from it all. Stub your toe? Put on something REALLY loud and angry and let it block out the pain signals. Works with broken hearts too, ask any teenager.
Anyway. Giving birth to a human out of your foof. The music admittedly might not help towards the end of it, but if the first part is going to be a muscular endurance test lasting days on end, I'd better get prepared with with as many psychological tricks as I can read up about. And two lovely, lovely TENs machines with their sticky stinging pads all over my back all at full electrocuting power.