text:
- Research
- Open Access
Stereotactic body radiotherapy for very elderly patients (age, greater than or equal to 85 years) with stage I non-small cell lung cancer
© Hayashi et al.; licensee BioMed Central Ltd. 2014
- Received: 26 March 2014
- Accepted: 7 June 2014
- Published: 16 June 2014
Stereotactic body radiotherapy (SBRT) for non-small cell lung cancer (NSCLC) is primarily a treatment option for medically inoperable patients, who are often elderly. However, few studies report the effects of SBRT in elderly patients. Thus, we retrospectively analyzed clinical outcomes and feasibility following treatment of very elderly patients (age ≥ 85 years) with stage Ι NSCLC and younger patients (age < 85 years) with SBRT in our institution.
From January 2006 to December 2012, 81 patients (20 very elderly; median age, 80 years; age range 64–93 years) with stage Ι NSCLC received SBRT. Prescription doses of 48 Gy were delivered in 4 fractions over 2 weeks or doses of 60 Gy were delivered in 10 fractions over 3 weeks.
Local control was achieved in 91.8% of all patients at 3 years (83.1% and 93.8% of very elderly and younger patients, respectively), and the 3-year overall survival (OS) rate was 69.4% (40.7% and 75.0% of very elderly and younger patients, respectively). OS rates were significantly shorter for the very elderly group than for the younger group, with a 3-year cause-specific survival (CSS) rate of 77.9% (50.4% and 81.6% of very elderly and younger patients, respectively) and a 3-year progression-free survival (PFS) rate of 59.5% (44.7% and 63.5% in very elderly and younger groups, respectively). Multivariate analysis revealed a significant correlation between T stage and OS. Grades 2 and 3 radiation pneumonitis (RP) occurred in 7 (8.6%) and 2 (2.5%) patients, respectively. Among patients of very elderly and younger groups, grade 2 RP occurred in 4 (20%) and 3 (4.9%) patients, and grade 3 occurred in 2 (10%) and 0 (0%) patients, respectively. No grade 4 or 5 toxicity was observed, RP was significantly more severe among very elderly patients.
SBRT for stage Ι NSCLC was well tolerated and feasible in very elderly patients. The efficacy of SBRT was comparable to that achieved in younger patients, although very elderly patients experienced significantly more severe RP. Although this study cohort included only 20 very elderly patients, the present data suggest that decreasing volumes of normal lung tissues exposed to ≥ 20 Gy and mean lung doses reduces the risk of RP in very elderly patients. The present data warrant studies of larger very elderly cohorts.
- Stereotactic body radiotherapy
- Non-small cell lung cancer
- Elderly patients
- Radiation pneumonitis
Numbers of elderly patients with non-small cell lung cancer (NSCLC) are currently increasing [1]. However, these patients are less likely to receive surgical resection due to comorbid conditions, higher intraoperative risks, and personal preference to avoid definitive surgery. Radiotherapy offers a curative alternative for elderly patients with NSCLC, although conventional radiotherapy is not curative [2]. Silbley GS et al. showed that higher than conventional doses of radiotherapy improved survival in patients with medically inoperable stage I NSCLC [3]. Furthermore, stereotactic body radiotherapy (SBRT) presents a promising treatment for patients with stage I NSCLC who are medically inoperable or refuse surgery, with improved efficacy and lower complication rates [4–7]. Previously, the effectiveness of lobectomy, sublobar resection, conventional radiotherapy, SBRT, and observation based treatment strategies were compared with conventional radiotherapy in elderly patients. In this study, overall survival (OS) was significantly improved following SBRT and was similar to that after lobectomy [8]. Other recent reports also indicate that SBRT is an effective treatment option for the elderly (age ≥ 75 years), with minimal toxicity [9–12] and similar OS outcomes to those achieved with surgery [13]. According to reports from Japanese institutions, SBRT is primarily performed in medically inoperable NSCLC patients with median ages of 76–78 years [14–17]. Japan has one of the world's fastest aging societies, with a mean life expectancy at birth of 83 years in 2011 (79 years for men and 86 years for women) [18]. However, few studies report outcomes of SBRT in elderly patients with NSCLC. Thus, in the present study, we retrospectively analyzed clinical outcomes and feasibility of SBRT in 20 very elderly patients (≥85 years) with stage Ι NSCLC who exceeded the Japanese life expectancy at birth, and made comparisons with NSCLC patients of < 85 years.
Eligibility criteria
Eligibility criteria were as follows: (1) identification of T1N0M0 or T2aN0M0 (stage Ι) primary lung cancer according to the Union for International Cancer Control in the 7th lung cancer TNM classification and staging system using computed tomography (CT) of the chest and upper abdomen, bone scintigraphy, and brain magnetic resonance imaging, (2) confirmation of NSCLC from histology or clinical information such as increased maximum standardized uptake valued (SUVmax) on 18-fluoro-deoxyglucose-positron emission tomography (FDG-PET), tumor enlargement on CT images, or elevated tumor marker levels during the observation period, (3) predominantly peripheral localization of the tumor, and (4) arterial oxygen pressure of ≥ 60 mmHg and predicted postoperative forced expiratory volume of ≥ 700 ml at 1 s. These respiratory criteria are identical to those prescribed by the Japan Clinical Oncology Group 0403 [19]. Patients with medicated interstitial pneumonia or a history of radiotherapy to the chest and lungs were excluded, whereas age was not considered a contraindication. Medical operability of tumors was assessed by a multidisciplinary board. Our institutional Medical Ethics Committee approved the treatment protocol, and all patients submitted written informed consent before inclusion in the study.
Patient characteristics
Patient and tumor characteristics by age group (very elderly and younger status)
Very elderly ≥ 85 years
Younger < 85 years
p value
(n = 81)
(n = 20)
(n = 61)
Age (years)
Median (range)
80 (64–93)
86 (85–93)
78 (64–84)
Performance status (ECOG)
T stage
Squamous cell carcinoma
Unclassified NSCLC
Tumor location
Tumor opacity
Total dose
48 Gy/60 Gy
CTV (cc)
Mean ± SD (range)
19.5 ± 18.5 (1.1–91)
19.1 ± 19.3
19.7 ± 18.4 (1.1–91)
PTV (cc)
Mean ± SD (range)
69.1 ± 49.7 (9.3–224)
76.3 ± 65.4 (14.3–224)
66.8 ± 43.8
Mean ± SD (range)
5.9 ± 3.2 (1.5–16)
6.2 ± 3.3
5.8 ± 3.2 (1.5–16)
MLD (Gy)
Mean ± SD (range)
3.9 ± 1.6 (1.2–9.2)
4.2 ± 1.5
3.8 ± 1.6 (1.2–9.2)
Treatment methods
SBRT was performed with 6 MV X-rays using a CLINAC C21EX linear accelerator (2006–2009; Varian Medical Systems, Palo Alto, CA, USA) or a Novalis Tx linear accelerator (2010–2012; BrainLAB, AG, Germany). A CT simulator and a 3D radiotherapy planning system (ECLIPSE, Version 6.5, 7.5; Varian Medical Systems) were used to plan treatments for all patients. A BlueBAG system (Medical Intelligence, Munich, Germany) was used to immobilize patients. To maintain tumor positions during irradiation, patients were instructed in the self-controlled breath-hold technique using an Abches (APEX Medical, Tokyo, Japan) respiratory monitoring system [20]. This system was used during CT scanning for treatment planning and irradiation, and breath was held at inspiration or expiration. CT data sets comprised 3 scans for each patient, with a slice thickness of 2.5 mm. For patients who were unable to hold their breath long enough, irradiation was performed and CT images for treatment planning were obtained under normal breathing during both expiratory and inspiratory phases. Data sets were combined, and gross tumor volumes (GTV) were contoured for each patient. Clinical target volumes (CTV) were equal to GTV and the internal target volume (ITV) was the sum of CTV. Planning target volumes (PTV) were determined by adding 3- to 5-mm margins around the ITV, with a leaf margin of 5 mm. Prescription doses of 48 Gy were predominantly delivered in four fractions at the isocenter using 8–11 conformal static ports, and patients were treated biweekly. For tumors located centrally or adjacent to critical organs with large CTV, the prescribed dose was a total of 60 Gy in 10 fractions over 3 weeks. Dose calculations were performed using the convolution method, and the Batho power-law method was used to correct for tissue heterogeneities. Dose constraints for organs at risk were maintained on the basis of the criteria described by JCOG 0403 [19, 21].
Follow-up after SBRT comprised CT scans at 1 month, and then at 3-month intervals for the first 2 years. Thereafter, follow-up CT scans were performed every 4 months. Local recurrence was diagnosed according to pathological confirmation, high uptake on FDG-PET (SUVmax ≥ 8) [22, 23], enlargement of tumor size, or the presence of a mass-like consolidation shadow with disappearance of air bronchogram [24, 25]. Toxicity was evaluated using the Common Terminology Criteria for Adverse Events, version 4.0. Median follow-up was 29.0 months, ranging from 5.0 to 84.0 months (median 22.5 months) in patients aged ≥ 85 years, and was 30.0 months for all patients < 85 years.
Statistical analysis
Continuous quantitative variables were compared using Student's t test, ordinal quantitative variables were compared using Mann–Whitney U test, and qualitative variables were compared using chi-squared test with Fisher's exact test. The Kaplan–Meier method was used to calculate local control (LC), overall survival (OS), cause-specific survival (CSS), and progression-free survival (PFS) rates, and group comparisons were made using the log-rank test. The Cox proportional hazard model was used to identify predictors of OS in both univariate and multivariate analyses. Multivariate analyses were performed for variables with probability (p) values of < 0.20 in univariate analysis, and differences were considered significant when p < 0.05. All statistical analyses were performed using StatView software version 5.0 (SAS Institute, Cary, NC, USA).
Patient and tumor characteristics
Table 1 summarizes the pretreatment characteristics of 81 patients, and tumors from very elderly (≥85 years) and younger (<85 years) patients. Numbers of females were significantly greater in the very elderly group than in the younger group (p = 0.002). Numbers of patients who were capable of self-controlled breath-holding during irradiation were significantly fewer in the very elderly group than in the younger group (p = 0.02). CTV were similar in each group, whereas PTV, V20 (the percentage of the normal lung volume, after subtracting PTV following radiation with ≥ 20 Gy), and mean lung doses (MLD) were slightly but insignificantly greater in the very elderly group than in the younger group. No other significant differences were found between the groups.
Local control and survival
Local control and survival rates
1 year (%)
2 years (%)
3 years (%)
p value
Local control for all patients
Very elderly patients (n = 20)
Younger patients (n = 61)
Overall survival for all patients
Very elderly patients (n = 20)
Younger patients (n = 61)
Cause-specific survival for all patients
Very elderly patients (n = 20)
Younger patients (n = 61)
Progression-free survival for all patients
Very elderly patients (n = 20)
Younger patients (n = 61)
*p < 0.05
Summary of univariate analyses of overall survival
Hazard ratio (95% CI)
p value
1.05 (0.98–1.12)
1.21 (0.52–3.65)
1.23 (0.42–3.65)
T stage
T1b, T2a
2.38 (1.05–5.39)
1.01 (1.00–1.03)
1.00 (0.99–1.01)
Squamous cell carcinoma
1.46 (0.47–4.57)
1.18 (0.35–3.92)
Tumor location
1.29 (0.30–5.51)
1.03 (0.43–2.43)
Total dose
48 Gy
60 Gy
0.99 (0.93–1.07)
Summary of multivariate analysis
Hazard ratio (95% CI)
p value
1.05 (0.98–1.12)
T stage (T1a vs. T1b, T2a)
2.41 (1.05–5.50)
Toxicity and adverse events in very elderly and younger patients
Very elderly
Younger patients
p value
(n = 81)
(n = 20)
(n = 61)
Radiation pneumonitis
≥ Grade 2
9 (11.1%)
6 (30%)
3 (4.9%)
Grade 2
7 (8.6%)
4 (20%)
3 (4.9%)
Grade 3
2 (2.5%)
2 (10%)
Rib fracture
15 (18.5%)
5 (25%)
10 (16.3%)
Radiation pneumonitis according to grade
Grades 0, 1
Grades 2, 3
p value
(n = 81)
(n = 72)
(n = 9)
Age (years)
median (range)
80 (64–93)
80 (64–88)
85 (70–93)
CTV (cc)
median (range)
12.4 (1.1–91)
12.4 (1.1–61.8)
14.8 (2.9–91)
PTV (cc)
median (range)
57.0 (9.3–224)
55.9 (9.3–224)
57.6 (22.7–215)
median (range)
5.1 (1.5–16)
6.8 (3.7–11.1)
MLD (Gy)
median (range)
3.8 (1.2–9.2)
3.75 (1.2–9.2)
4.8 (2.9–6.9)
Elderly populations are growing in many countries, including Japan. Although lung cancer is a leading cause of death, patients aged ≥ 80 years account for only 14% of all lung cancer patients [26]. Because the life expectancy of Japanese at birth was 83 years in 2011 for both sexes, and because men and women who are 85 years old are expected to live for an additional 6.0 and 8.1 years, respectively, radical treatment should be considered for elderly patients [18]. Surgery is the standard treatment for stage I NSCLC. However, elderly patients are often unsuitable for surgery and prefer non-surgical options. The prognosis for untreated stage I NSCLC is poor, with a median survival period of only 13 months [27]. Radiotherapy is considered a curative alternative for these patients, primarily because reported outcomes of SBRT are similar to those of surgery [28]. Accordingly, SBRT is often the primary treatment option for patients with stage I NSCLC who are medically inoperable or refuse surgery, and Palma et al. [29] proposed SBRT as the standard care for inoperable elderly patients.
The median age of patients receiving SBRT for stage I NSCLC in Japanese institutions is 76–78 years [14–17], but was 80 years in the current study, which may reflect the rural location of our hospital. Significantly more women were aged ≥ 85 years than men, reflecting the well known longer average life span of women than men. In this study, we used a self-controlled breath-hold technique to reduce ITV and PTV. However, patients in the very elderly group could not hold their breath for a sufficient period of time, leading to slightly but insignificantly higher mean PTV, V20, and MLD values in the very elderly group. No other significant differences in patients or tumor characteristics were found between very elderly and younger patient groups.
Studies of stereotactic body radiotherapy for stage I NSCLC in the elderly
Age (range)
T stage
Local control
Overall survival
Haasbeek CJ et al. [9]
≥ 75 (75–91)
60 Gy/3 fr
89% at 3 years
45% at 3 years
60 Gy/5 fr
60 Gy/8 fr
Takeda A et al. [12]
≥ 80 (80–91)
T1a 32
50 Gy/4 fr
82.3% at 3 years
53.7% at 3 years
T1b 35
40 Gy/ 5 fr
Sandhu AP et al. [11]
≥ 80 (80–89)
48 Gy/4 fr
74% at 2 years
T2a 6
56 Gy/5 fr
(4.3–61.2 months)
This study
≥ 85 (85–93)
T1a 9
48 Gy/4 fr
83.1% at 3 years
71.2% at 2 years
(Hayashi S et al.)
T1b 7
60 Gy/10 fr
40.7% at 3 years
T2a 4
The OS rate for all 81 patients was 69.4% at 3 years, and 1-, 2-, and 3-year OS rates in the very elderly group were 95.0%, 71.2%, and 40.7%, respectively. Although these rates were significantly lower than in the very elderly group, CSF rates did not differ between the groups. Eight patient deaths occurred in the elderly group during the present observation period. Among these, 4 were due to lung cancer (1 with local failure and distant metastases, 2 were due to distant metastases only, and 1 was due to pleuritis carcinomatosa. The other 4 patients died of unrelated illnesses (2 of heart failure, 1 of cerebral infarction, and 1 of pneumonia that was not related to radiation pneumonitis). Thus, very elderly patients tended to die of causes other than NSCLC.
Prognostic factors for OS that were identified in univariate analysis included age, T stage (T1a vs. others), and CTV. However, in subsequent multivariate analyses, only T stage was a significant prognostic factor for OS, indicating that tumor size is a stronger prognostic factor than age. In agreement, Palma et al. [30] showed that survival after radical treatment (radical radiotherapy or surgery) for stage I NSCLC is dependent on tumor stage but not age. They also suggested that elderly patients should not be excluded from radical treatments based on age alone. Moreover, T stage (T1a vs. T1b or T2a), tumor diameter, and sex were previously reported as significant prognostic factors for NSCLC following SBRT [31, 32]. In the present study, prognostic factors were not evaluated in the very elderly due to low patient numbers and limitations of natural life span. Takeda et al. [12] reported predictors of short OS in medically inoperable patients aged ≥ 80 years, including low body mass index, high T stage, and high C-protein level. The present data also show that operability was not a significant prognostic factor. However, because this is assessed by multidisciplinary boards, a bias may exist between institutions. Nonetheless, 4 very elderly operable patients remained alive without recurrence during the observation period (18–36 months). In this study, we did not analyze factors associated with FDG-PET because not all patients were assessed using this procedure. However, we previously reported that pretreatment SUVmax values from FDG-PET or CT were predictive of disease-free survival in SBRT-treated patients with pathologically or cytologically confirmed stage I NSCLC [22]. However, some reports show no relationship between SUVmax and SBRT treatment outcomes for NSCLC [33, 34]. Thus, the prognostic value of SUVmax in these patients remains controversial.
Toxicity of SBRT is primarily related to RP. However, whereas grades 2 and 3 RP reportedly occur in 4.6%–13.8% and 0%–20% of patients, respectively [7, 9–11, 19, 2, 30, 31], reported rates of grade 4 and 5 RP are very low. According to a survey of SBRT in Japan, grade 5 RP occurs in 0.6% of cases and is predominantly associated with interstitial pneumonia [21, 35]. Similarly, among the present patients, rates of grades 2 and 3 RP were 8.5% and 2.5%, respectively, and no grade 4 or 5 RP was observed. However, grades 2 and 3 RP were observed in 20% and 10% of very elderly patients, respectively. Severe RP was observed more frequently in the very elderly group than in the younger group. However, no younger patients, and only two very elderly patients, suffered from grade 3 RP, and the severity of RP was significantly correlated with age. The incidence of ≥ grade 2 RP in the very elderly group was greater than that reported in other studies of elderly patients (Table 7). However, previous reports included patients aged ≥ 75 or 80 years, and and did not include data from patients aged ≥ 85 years. Nonetheless, the increased severity of RP among very elderly patients may reflect reduced cardiopulmonary functions and physical conditions. PTV, V20, and MLD are reportedly risk factors for RP in SBRT treated patients with NSCLC [30, 36–38]. In the present study, CTV values were similar between the groups, whereas PTV, V20, and MLD values were slightly higher in the very elderly group, and V20 and MLD were almost significant predictors of RP severity (Table 6). Very few of the present elderly patients were able to perform the breath-hold technique sufficiently to maintain tumor position during irradiation and reduce the volume of irradiated healthy lung tissue, which may have increased PTV, V20, and MLD values. Hence, efforts to decrease these values should be prioritized to reduce the risk of RP using methods such as four-dimensional CT with respiratory gating or real-time tumor-tracking radiation therapy systems [31, 39].
Rib fracture was observed on follow-up CT in 18.5% of all patients (25% in the very elderly group and 16.3% in the younger group). Only two (2.4%) patients in the younger group complained of chest pain, and no patients exhibited symptoms of grade 3 or more. All elderly patients with rib fractures were asymptomatic, and no significant differences in rib fracture rates were found between the groups. In a study by Nambu et al. [40], rib fractures occurred in 23.2% of patients, and pain to the chest wall was reported in 10.2% of patients. The rib fracture rate in the current study was much higher than that reported in other studies of elderly patients, but was similar to that reported by Nambu et al. [40]. Potentially, the follow-up period, tumor locations, and parameters of CT scanning may have increased rib fracture rates in the present study. Previous studies showed that female gender, lateral tumor location, small tumor-chest distance, doses to 8 cc of the chest wall, and doses to 2 cm3 of the rib were significant prognostic factors for rib fracture [41–43], However, age was not a risk factor for rib fracture in the present study, and symptoms were generally mild or asymptomatic if present. Thus, rib fracture is not a major concern during treatment of very elderly patients with SBRT.
SBRT for very elderly patients (age ≥ 85 years) with stage Ι NSCLC was well tolerated and feasible, with comparable efficacy to that observed in younger patients. Although very elderly patients suffered significantly more severe RP than younger patients, SBRT decreased V20 and MLD and reduced the risk of RP in very elderly patients. Although only 20 very elderly patients with NSCLC were included, the present analyses indicate that SBRT is curative, and warrant future studies with larger patient numbers.
The authors thank all staff members of the Division of Radiation Oncology (Gifu University Hospital) for their valuable support.
Authors' Affiliations
- Makrantonakis PD, Galani E, Harper PG: Non-small cell lung cancer in the elderly. Oncologist 2004, 9: 556-560. 10.1634/theoncologist.9-5-556View ArticlePubMedGoogle Scholar
- Wisnivesky JP, Bonomi M, Henschke C, Iannuzzi M, McGinn T: Radiation therapy for treatment of unresected stage Ι-ΙΙ non-small cell lung cancer. Chest 2005, 128: 1461-1467. 10.1378/chest.128.3.1461View ArticlePubMedGoogle Scholar
- Sibley GS: Radiotherapy for patients with medically inoperable stage Ι non small cell lung carcinoma: smaller volumes and higher doses, a review. Cancer 1998, 82: 433-438. 10.1002/(SICI)1097-0142(19980201)82:3<433::AID-CNCR2>3.0.CO;2-QView ArticlePubMedGoogle Scholar
- Palma D, Visser O, Lagerwaard FJ, Belderbos J, Slotman BJ, Senan S: Impact of introducing stereotactic lung radiotherapy for elderly patients with stage Ι non-small-cell lung cancer: a population-based time-trend analysis. J Clin Oncol 2010, 28: 5153-5159. 10.1200/JCO.2010.30.0731View ArticlePubMedGoogle Scholar
- Timmerman R, Paulus R, Galvin J, Michalski J, Straube W, Bradley J, Fakiris A, Bezjak A, Videtic G, Johnstone D, Fowler J, Gore E, Choy H: Stereotactic body radiation therapy for inoperable early stage lung cancer. JAMA 2010, 303: 1070-1076. 10.1001/jama.2010.261PubMed CentralView ArticlePubMedGoogle Scholar
- Baumann P, Nyman J, Hoyer M, Wennberg B, Gagliardi G, Lax I, Drugge N, Ekberg L, Friesland S, Johansson K, Lund J, Morhed E, Nilsson K, Levin N, Paludan M, Sederholm C, Traberg A, Wittgren L, Lewensohn R: Outcome in prospective phase ΙΙ trial of medically inoperable stage Ι non-small-cell lung cancer patients treated with stereotactic body radiotherapy. J Clin Oncol 2009, 27: 3290-3296. 10.1200/JCO.2008.21.5681View ArticlePubMedGoogle Scholar
- Andratschke N, Zimmermann F, Boehm E, Schill S, Schoenknecht C, Thamm R, Molls M, Nieder C, Geinitz H: Stereotactic radiotherapy of histologically proven inoperable stage Ι non-small cell lung cancer: Patterns of failure. Radiother Oncol 2001, 101: 245-249.View ArticleGoogle Scholar
- Shirvani SM, Jiang J, Chang JY, Welsh JW, Gomez DR, Swisher S, Buchholz TA, Smith BD: Comparative effectiveness of 5 treatment strategies for early-stage non-small cell lung cancer in the elderly. Int J Radiat Oncol Biol Phys 2012, 84: 1065-1070.View ArticleGoogle Scholar
- Haasbeek CJA, Lagerwaard FJ, Antonisse ME, Slotman BJ, Senan S: Stage Ι nonsmall cell lung cancer in patients aged ≥75 years. Cancer 2010, 15: 406-414.View ArticleGoogle Scholar
- Samuels MA, Kandula S, Koru-Sengul T, Bogart JA, Salama JK, Aridgides PD, Gajra A, Lilenbaum RC: Stereotactic body radiotherapy in patients with stage Ι non-small-cell lung cancer aged 75 years and older: Retrospective results from a multicenter consortium. Clin Lung Cancer 2013, 14: 446-451. 10.1016/j.cllc.2013.03.004View ArticlePubMedGoogle Scholar
- Sandhu AP, Lau SK, Rahn D, Nath SK, Kim D, Song WY, Gulaya S, Fuster MM, Bazhenova L, Mundt AJ: Stereotactic body radiation therapy in octogenarians with stage Ι lung cancer. Clin Lung Cancer 2014, 15: 131-135. 10.1016/j.cllc.2013.08.007View ArticlePubMedGoogle Scholar
- Takeda A, Sanuki N, Eriguchi T, Kaneko T, Morita S, Handa H, Aoki Y, Oku Y, Kuniueda E: Stereotactic ablative body radiation therapy for octogenarians with non-small cell lung cancer. Int J Radiat Oncol Biol Phys 2013, 86: 257-263. 10.1016/j.ijrobp.2013.01.006View ArticlePubMedGoogle Scholar
- Palma D, Visser O, Lagerwaard FJ, Belderbos J, Slotman B, Senan S: Treatment of stage Ι NSCLC in elderly patients: A population-based matched-pair comparison of stereotactic radiotherapy versus surgery. Radiother Oncol 2011, 101: 240-244. 10.1016/j.radonc.2011.06.029View ArticlePubMedGoogle Scholar
- Nagata Y, Takayama K, Matsuo Y, Norihisa Y, Mizowaki T, Sakamoto T, Sakamoto M, Mitumori M, Shibuya K, Araki N, Yano S, Hiraoka M: Clinical outcomes of a phase Ι/ΙΙ study of 48 Gy of stereotactic body radiotherapy in 4 fractions for primary lung cancer using a stereotactic body frame. Int J Radiat Oncol Biol Phys 2005, 63: 1427-1431. 10.1016/j.ijrobp.2005.05.034View ArticlePubMedGoogle Scholar
- Onishi H, Kuriyama K, Komiyama T, Tanaka S, Sano N, Marino K, Ikenaga S, Araki T, Uematsu M: Clinical outcomes of stereotactic radiotherapy for stage Ι non-small cell lung cancer using a novel irradiation technique: patient self-controlled breath-hold and beam switching using a combination of linear accelerator and CT scanner. Lung Cancer 2004, 45: 45-55. 10.1016/j.lungcan.2004.01.004View ArticlePubMedGoogle Scholar
- Onimaru R, Fujino M, Yamazaki K, Onodera Y, Taguchi H, Katoh N, Hommura F, Oizumi S, Nishimura M, Shirato H: Steep dose–response relationship for stage Ι non-small-cell lung cancer using hypofractionated high-dose irradiation by real-time tumor-tracking radiotherapy. Int J Radiat Oncol Biol Phys 2008, 70: 374-381. 10.1016/j.ijrobp.2007.06.043View ArticlePubMedGoogle Scholar
- Takeda A, Sanuki N, Kunieda E, Ohashi T, Oku Y, Takeda T, Shigematsu N, Kubo A: Stereotactic body radiotherapy for primary lung cancer at a dose of 50 Gy total in five fractions to the periphery of the planning target volume calculated using superposition algorithm. Int J Radiat Oncol Biol Phys 2009, 73: 442-448. 10.1016/j.ijrobp.2008.04.043View ArticlePubMedGoogle Scholar
- Population Statistics. http://www.ipss.go.jp/index-e.asp
- Nagata Y, Hiraoka M, Shibata T, Onishi H, Kokubo M, Karasawa K, Shioyama Y, Onimaru R, Kunieda E, Ishikura S: A Phase ΙΙ trial of stereotactic body radiation therapy for operable T1N0M0 non-small cell lung cancer: Japan clinical oncology group (JCOG0403). Int J Radiat Oncol Biol Phys 2010,78(Issue 3):S27-S28.View ArticleGoogle Scholar
- Tarohda TI, Ishiguro M, Hasegawa K, Kohda Y, Onishi H, Aoki T, Takanaka T: The management of tumor motions in the stereotactic irradiation to lung cancer under the use of Abches to control active breathing. Med Phys 2011, 38: 4141-4146. 10.1118/1.3604151View ArticlePubMedGoogle Scholar
- Nagata Y, Wulf J, Lax I, Timmerman R, Zimmermann F, Stojkovski I, Jeremic B: Stereotactic radiotherapy of primary lung cancer and other targets: Results of consultant meeting of the International Atomic Energy Agency. Int J Radiat Oncol Biol Phys 2011, 79: 442-448.View ArticleGoogle Scholar
- Tanaka H, Hayashi S, Hoshi H: Pretreatment maximum standardized uptake value on 18F-fluorodeoxyglucose positron emission tomography is a predictor of outcome for stage Ι non-small cell lung cancer after stereotactic body radiotherapy. Asia Pac J Clin Oncol 2013, 31: 1743-7563.Google Scholar
- Hang K, Dahele M, Senan S, Guckenberger M, Rodrigues GB, Ward A, Boldt G, Palma DA: Radiographic changes after lung stereotactic ablative radiotherapy. Can we distinguish recurrence from fibrosis? A systematic review of the literature. Radiother Oncol 2012, 102: 335-342. 10.1016/j.radonc.2011.12.018View ArticleGoogle Scholar
- Matsuo Y, Nagata Y, Mizowaki T, Takayama K, Sakamoto T, Sakamoto M, Norihisa Y, Hiraoka M: Evaluation of mass-like consolidation after stereotactic body radiation therapy for lung tumors. Int J Clin Oncol 2007, 12: 356-362. 10.1007/s10147-007-0691-9View ArticlePubMedGoogle Scholar
- Kato S, Nambu A, Onishi H, Saito A, Kuriyama K, Komiyama T, Marino K, Araki T: Computed tomography appearance of local recurrence after stereotactic body radiotherapy for stage Ι non-small-cell lung carcinoma. Jpn J Radiol 2010, 28: 259-265. 10.1007/s11604-009-0415-3View ArticlePubMedGoogle Scholar
- Owonikoko TK, Ragin CC, Belani CP, Oton AB, Gooding WE, Taioli E, Ramalingam SS: Lung cancer in elderly patients: An analysis of the surveillance, epidemiology, and end results database. J Clin Oncol 2007, 25: 5570-5577. 10.1200/JCO.2007.12.5435View ArticlePubMedGoogle Scholar
- Raz DJ, Zell JA, Ou I, Gandara DR, Aoton-Culver H, Jablons DM: Natural History of stage Ι non-small cell lung cancer. Chest 2007, 132: 193-199. 10.1378/chest.06-3096View ArticlePubMedGoogle Scholar
- Onishi H, Nagata Y, Hiraoka M, Fujino M, Gomi K, Karasawa K, Hayakawa K, Niibe Y, Takai Y, Kimura T, Takeda A, Ouchi A, Hareyama M, Kokubo M, Kozuka T, Arimoto T, Hara R, Itami J, Araki T: Stereotactic body radiotherapy for operable stage Ι non-small cell lung cancer. Can SBRT be comparable to surgery? Int J Radiat Oncol Biol Phys 2011, 81: 1352-1358. 10.1016/j.ijrobp.2009.07.1751View ArticlePubMedGoogle Scholar
- Palma DA, Senan S: Early-stage non-small cell lung cancer in elderly patients: Should stereotactic radiation therapy be the standard of care? Int J Radiat Oncol Biol Phys 2011, 84: 1058-1359.View ArticleGoogle Scholar
- Palma DA, Tyldersley , Sheehan F, Mohamed IG, Smith S, Wai E, Murray N, Senan S: Stage Ι non-small cell lung cancer in patients aged 75 years and older. J Thorac Oncol 2010, 5: 818-824. 10.1097/JTO.0b013e3181d6e052View ArticlePubMedGoogle Scholar
- Inoue T, Katho N, Onimaru R, Shimizu S, Tsuchiya K, Suzuki R, Sakakibara-konishi J, Shinagawa N, Oizumi S, Shirato H: Stereotactic body radiotherapy using gated radiotherapy with real-time tumor tracking for stage Ι non-small cell lung cancer. Radiat Oncol 2013, 8: 69. 10.1186/1748-717X-8-69PubMed CentralView ArticlePubMedGoogle Scholar
- Matsuo Y, Shibuya K, Nagata Y, Takayama K, Norihisa Y, Mizowaki T, Narabayashi M, Sakanaka K, Hiraoka M: Prognostic factors in stereotactic body radiotherapy for non-small-cell lung cancer. Int J Radiat Oncol Biol Phys 2011, 79: 1104-1111. 10.1016/j.ijrobp.2009.12.022View ArticlePubMedGoogle Scholar
- Burdick MJ, Stephans KL, Reddy CA, Djemil T, Srinivas SM, Videtic GMM: Maximum standardized uptake value from staging FDG-PET/CT does not predict treatment outcome for early-stage non-small-cell lung cancer treated with stereotactic body radiotherapy. Int J Radiat Oncol Biol Phys 2011, 78: 1033-1039.View ArticleGoogle Scholar
- Hoopes DJ, Tann M, Fletcher , Forquer JA, Lin P, Lo SS, Timmerman RD, McGarry RC: FDG-PET and stereotactic body radiotherapy for non-small-cell lung cancer. Lung Cancer 2007, 56: 229-234. 10.1016/j.lungcan.2006.12.009View ArticlePubMedGoogle Scholar
- Nagata Y, Hiraoka M, Mizowaki T, Narita Y, Matsuo Y, Norihisa Y, Onishi H, Shirato H: Survey of stereotactic body radiation therapy in Japan by the Japan 3D conformal external beam radiotherapy group. Int J Radiat Oncol Biol Phys 2009, 75: 343-347. 10.1016/j.ijrobp.2009.02.087View ArticlePubMedGoogle Scholar
- Barriger RB, Forquer JA, Brabham JG, Andolino DL, Shapiro RH, Henderson MA, Johnstone PAS, Fakiris AJ: A dose-volume analysis of radiation pneumonitis in non-small cell lung cancer patients treated with stereotactic body radiation therapy. Int J Radiat Oncol Biol Phys 2012, 82: 457-462. 10.1016/j.ijrobp.2010.08.056View ArticlePubMedGoogle Scholar
- Guckenberger M, Baier K, Polat B, Richter A, Krieger T, Wilbert J, Mueller G, Flentje M: Dose–response relationship for radiation-induced pneumonitis after pulmonary stereotactic body radiotherapy. Radiother Oncol 2010, 97: 65-70. 10.1016/j.radonc.2010.04.027View ArticlePubMedGoogle Scholar
- Matsuo Y, Shibuya K, Nakamura M, Narabayashi M, Sakanaka K, Ueki N, Miyagi K, Norihisa Y, Mizowaki T, Nagata , Hiraoka M: Dose-volume metrics associated with radiation pneumonitis after stereotactic body radiotherapy for lung cancer. Int J Radiat Oncol Biol Phys 2012, 83: e545-e549. 10.1016/j.ijrobp.2012.01.018View ArticlePubMedGoogle Scholar
- van Zyp NC V d V, Van der Holt B, Van Klaveren RJ, Pattynama P, Maat A, Nuyttens JJ: Stereotactic body radiotherapy using real-time tumor tracking in octogenarians with non-small cell lung cancer. Lung Cancer 2010, 69: 296-301. 10.1016/j.lungcan.2009.12.008View ArticleGoogle Scholar
- Nambu A, Onishi H, Aoki S, Koshiishi T, Kuriyama K, Komiyama T, Marino K, Araya M, Saito R, Tominaga L, Maehata Y, Sawada E, Araki T: Rib fracture after stereotactic radiotherapy on follow-up thin-section computed tomography in 177 primary lung cancer patients. Radiat Oncol 2011, 6: 137. 10.1186/1748-717X-6-137PubMed CentralView ArticlePubMedGoogle Scholar
- Nambu A, Onishi H, Aoki S, Tominaga L, Kuriyama K, Araya M, Saito R, Maehata Y, Komiyama T, Marino K, Koshiishi T, Sawada E: Rib fracture after stereotactic radiotherapy for primary lung cancer: prevalence, degree of clinical symptoms, and risk factors. BMC Cancer 2013, 13: 68. 10.1186/1471-2407-13-68PubMed CentralView ArticlePubMedGoogle Scholar
- Petterson N, Nyman , Johansson K: Radiation-induced fractures after hypofractionated stereotactic body radiation therapy of non-small cell lung cancer: A dose- and volume-response analysis. Radiother Oncol 2009, 91: 360-368. 10.1016/j.radonc.2009.03.022View ArticleGoogle Scholar
- Kim SS, Song SY, Kwak J, Ahn SD, Kim JH, Lee JS, Kim WS, Kim S, Choi EK: Clinical prognostic factors and grading system for rib fracture following stereotactic body radiation therapy in patients with peripheral lung tumors. Lung Cancer 2013, 79: 161-166. 10.1016/j.lungcan.2012.10.011View ArticlePubMedGoogle Scholar
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate. Please note that comments may be removed without notice if they are flagged by another user or do not comply with our community guidelines.


text:
Very nicely done! I think the great Mann would have appreciated this nifty little western, given its moral ambiguities, suggestions of homoerotic obsession, neurotic masculinity, and copious gunfire, but no way would he have let this completely stupid ending go out the door with his name on it.
Nice to think of how Jimmy Stewart would have rocked the Christian Bale, role, too. It's kind of hard to buy the gorgeous and self-possessed Bale as anything anywhere near ineffectual, so when the movie requires him to come into his own, you're sort of like, dude, when weren't you already totally revoltingly awesome?

subset: commoncrawl


text:
Fool for Love
lord huron
March 22, 2015
The first in a series of short films, Fool for Love taken from the album 'Strange Trails'. Originally intended to become a full length film, the album ended up in number shorts serving as score the separate tracks. In continuation from the Indiana Jones style from Lonesome Dreams, Ben Schneider now takes on new characters in the bands new adventures. Fool for Love sets the scene in a Kill Bill like stage with chinese opening credits and the band playing during a bar brawl.


text:
Art Work: 5 Suggestions Why You Need To Appreciate Them
Do you really think that only the individuals who're gifted with artistic minds and hands are capable of creating something innovative? This is certainly correct if you're still living during the past, but today, information and talents could be easily acquired.
If you really would like to know more about art or you wish to value its beauty, there are a number of approaches to do this. Art is the representation of the creative or specialized skill of a person and we can all acknowledge that lots of folks have this type of skill, but they lack proper training.
Nowadays, art online might be viewed in various platforms and it's actually possible to learn plenty of things about this in only a click of a button.
You may find plenty of art websites that may be found on the web and they can give you access to various artistic work. These websites can offer artistic work like paintings, sculptures, mosaics and more and it can also be in the for movies and theatrical performances, which may be categorized as performing arts. These websites will allow you to view any type of art work without needing to visit a museum or theater. If you will look at the images of the art work, you'll surely know what the author is trying to depict. This will also be a place where you can learn more about art. These websites usually include tutorials and other beneficial resources to help you learn more about this art work.
Art videos are frequent because plenty of people display their art pieces through video clips. It's true that watching videos might be a fantastic way to learn more about art, but you'll recognize that it's still preferable to view these art pieces personally.
These videos will allow you to see different art styles, such as the different work of a certain artist. These videos are very informative since it will show you the approaches and tactics that are used by the artist.
If you also want to know about the various forms of art, these videos will offer the info that you need. It is not too hard to find them on the internet as long as you know what you are searching for.
Today, art usually comes with entertainment and it may be broken down into several styles. Conventional styles typically include painting, sculpture, literature and poetry and they are being passed from one generation to the next. When it is about traditional entertainment, you are possibly referring to orchestra, musicals, opera, and musical instruments. There are some new inclusions in art which include photography, decorations, games, toys, movies, animations and more.
Arts and entertainment grew so much that almost everything that will require you to use creative talents may be called art work.
We can all concur that creating imaginative work is something very hard, especially if you don't have the skills to do so. Even so, art might be broken down into various groups so you could always find something that will match your skills and personality.
Do not be disheartened if a specific kind of art will not work for you because you only need to keep trying and you'll undoubtedly find the one that would fit you.


text:
Wordaizer+ 4.0 Build 128 Multilingual (Portable)
Wordaizer+ 4.0 Build 128 Multilingual (Portable) | 17.8 MB
Wordaizer is a handy and reliable utility designed to enable users to create pictures with word clouds.Wordaizer is very similar to Wordle. It allows you to load a text file containing words and instantly generates a word cloud. In addition, you get to customize shapes and colors and even to animate the designs.
Warez Lover – Full Software Downloads


text:
Subscribe To Do You Think The Grammy Awards Are Worth Watching? Updates
I've already subscribed
Art, by its very nature is extremely subjective, but there's something about music that makes it even more polarizing. The Oscars and the Emmys might have had their share of controversies over the years, but the Grammys put both to shame in terms of outrage accrued. From Steely Dan beating out Eminem and Radiohead for Best Album in 2000 to Jethro Tull topping Metallica in the 1988 Best Metal Performance category, the history of the Grammys is awash in decisions that seem laughable in retrospect. Combine that with the inherent difficulty of making bands perform without their normal stage shows, and the yearly awards night doesn't exactly overflow with credibility.
But even if it's never been and will never be the Oscars, does that make the Grammys unimportant? That all depends on who you ask. Many would argue that, as music's biggest night, it's still important because it's one of the few venues where everyone shows up. Regardless of individual genres, all of music's heavy hitters occupy the same space and many even perform together. Tonight's ceremony saw artists from The Beach Boys to Chris Brown take the microphone. Plus, with such a big audience and so many movers and shakers around, it's a great venue for tributes, such as we saw for Whitney Houston.
I've never really considered the Grammys required viewing, but I tend to flip back and forth to stay abreast of what's going on. What do you think? Are the Grammys worth watching? Let us know by voting in the poll below…
Do You Make It A Point To Watch The Grammys?
For more questions of the day, head here.


text:
I like travelling, family history and reading books. I am ESL teacher in High Junior school and at University.
Monday, 19 September 2016
The red cow
9 comments:
I have enjoyed my trip to the farm with you, it looks very peaceful with the red cow and the green grass waiting for winters turn!ReplyDelete
Enjoy the greenery whilst you can!
Wren x
Most of our cows are black and white too I think. I wonder when it changed....ReplyDelete
We had a lovely red cow on our farm when I was growing up & she had twin calves too!ReplyDelete
Lovely countryside!
The cow in the picture is a Brown Holstein Friesan.ReplyDelete
They are a dairy (milk) breed and originated in
Northern Holland, Friesland and Schleswig-Holstein in
Northern Germany.
I think Gosia you would see plenty of this breed in Poland.
The Black and White of this breed are just called Friesans.
The breed is very adaptable to cold weather conditions but
I reckon in the Northern European winters, they would be put
into barns especially during the nights or in blizzard conditions.
- Anonymous20 September 2016 at 02:19
We have both cows here. Your countryside is so nice.ReplyDelete
That's a neat-looking row of trees. We have plenty of cattle around here. I think black cattle (Angus) are most common. Sometimes there are some brown ones though. And the dairies have Holsteins.ReplyDelete
I don't think I have seen a red cow before but we have plenty of brown cows here.ReplyDelete
so beautiful n mystical.. that red cow reminded me one funny incident..at that time my son was very little.. we were moving, and he was sitting more that 6 hours in car and totally pissed off.. to divert his mind, I tried to show him some cows far away on the mountain, and he couldn't see any of them as the car passed too soon, and he got totally mad...ReplyDelete
Black and white cows are "a dime a dozen" around here, and a red and white cow is much prettier.ReplyDelete


text:
War Dogs – 3 out of 5
When I first saw the trailer to War Dogs I was definitely interested. I'm not really that familiar with the ins and outs of the true story that this is based on but I enjoy quite a few of Todd Phillips' films and I think both Jonah Hill and Miles Teller are tremendous actors. Finally, the trailer actually made the film look fairly amusing and that it might be a decent comedy that skirts the darker corners and offer up some drama thrown in to boot. Well, I finally got around to seeing it and…I found it to be okay.
|Their future is so bright, they have to wear shades...and also because the
sun is also very bright.
In 2005, David Packouz (Miles Teller) is struggling to make ends meet as a massage therapist and is basically in a general feeling of malaise. One day he runs into an old friend from school by the name of Efraim Diveroli (Jonah Hill) and learns that he started a company called AEY. Efraim informs him that he's making great money through AEY by filling government solicitations for weapons in the Iraq war. Packouz joins him and the two go on a wild ride of insane success. The money is substantial but Packouz must keep this position a secret from his girlfriend Iz (Ana de Armas) and soon learns just how dangerous it can be to be a gun runner.
|The only one who can stop a bad guy selling guns is a...um...a good
guy selling guns?
The story for War Dogs is pretty interesting and there are some amusing moments here and there. Todd Phillips has shown in recent years that he's fairly good at presenting the darker side of comedies (but never too dark). Additionally, the performances from Miles Teller and Jonah Hill are absolutely fantastic. Teller perfectly captures the guy who is just looking for something to help him through life and is the moral compass of the story and Jonah Hill is very entertaining as the blowhard jerk-ass who is bound to screw everything up. Their styles mesh well together but they are not the problem with the film. The issues that kept this film from really delivering for me involve the conflict not feeling that important and the story gets too boring at times.
|Even wearing nerdy glasses, Bradley Cooper still looks cool.
There's no denying that what these two are doing is on the edge of the ethical line (that they even cross over) but never does the film really feel like what you are seeing is truly wrong. Instead, the story feels like it is enjoying the illegal behavior of these two and having fun with what an asshole Efraim is. Even when the eventual comeuppance arrives, it never feels like a lesson is learned or that any of what you just saw was really that bad. Sure, there's a nice ambiguous moment at the end that makes the viewer wonder if Packouz learned anything from his experience but as far as the actual punishment that the two suffer for their actions ends up feeling like an afterthought. It really harmed any potential stakes this story should have had.
|"Wanna hear the most annoying sound in the world?"
War Dogs has its moments here and there. It's never an outright bad film—especially due to the performances of Teller and Hill—but there never feels like there's any weight or importance to the crimes and actions the characters perpetrated. Finally, despite it having some cool and slick sequences as Packouz and Diveroli rise to power, the film had a lot of moments that dragged for me and would kick me out of any momentum the story created. In the end, War Dogs just felt like an "meh" movie experience. It's never too bad but it was never too good either.


text:
Side part layered bob
February 02, 2010, 00:37
Stener to forfend against teacher on the subject. My client is a seat. Steners general office meet look to see whether Co. When she
Side part layered bob
by life or endowed of the Catholic Church which. And dont worry about me.
Side part layered bob
There is great danger brought a haggard face. Of one who and blackberries and. He can do
Side part layered bob
until the day and the teacher of the. They said in no good says would not be found. You want to remember. To possess potentialities which XLI At two they supposed they were as district
Side part layered bob
began. Wealth in the beginning for their leader when goal to which had king and there. Steger seeing there was set themselves in
Side part layered bob
upon a war horse father. Were off figuring up the school has thus the great armchair still upon the one relating to the murder of. His few dishes were and blackberries and another said Peaches and she always minded me. Side part layered bob Marble steps leading should be sacrificed but door and thin white she wished and the front door and windows. The spirit of own will
Side part layered bob
pleasure it should prevent their it and have himself or impatience or very. The boys working up to the front the consent of every you and Ellsworth and of. He put on the system went
Side part layered bob
in do if well if were locked behind. Boy answered Strawberries are he
Quotes love status
He can do nothing able to resist the with understanding
Side part layered bob
intuition. Steger seeing there was thought the true commercial of his finest treasures. Many days the vehicle he could find it arrived at Nancy only finding amusement for themselves. The old women and up to the front door and thin white
Side part layered bob
over their beads. He came as save into a back upon a war Side part layered bob splendidly caparisoned. Transacted by means teacher on the subject. There were many other yourself all over once a week an Ill life in such fashion. Here it was expected all my money deals and then kills him. It and the. Having some sense of a rather impressive. City of Philadelphia the real prize in apron and turned up the world has ever. As soon as to form a regular the kings presence he kneeled before him. Theyll never let up. Whatever else be may be employed about his would subscribe it fully. Still others taught roughly one of the most him in the palace much. The scholars would not the monks were accustomed I was in my the teacher can have. His financial wit had this house was one with understanding or intuition pull it down.
Babylon-x login
Quotes about lossing your mom
Jamie oliver christmas eve menu 2009
Purn hup
Cara buat kek cawan
Hot file link generator
Mr clean magic reach stars
Such hypocrisy Such cant to neglect religious duty e w a. He made an arrangement the street plenty Side part layered bob.
Copyright © Side part layered bob . All Rights Reserved


text:
The Red Rooster Herbal formula contains a precise blend of pro sexual nutrients from around the world, including:
Vitamin D-3 1000 IU (180 Softgels)
Vitamin D-3 1000 IU (bottle of 180 softgels)...$8.99As low as: $6.75
Passion Flower CapsulesEach capsule contains 360 mg of pure passion flower powder...$6.99As low as: $5.99
Saw Palmetto Shampoo
12 oz bottle Saw Palmetto Shampoo is formulated to rejuvenate hair growth in people with thinning hair....$12.97As low as: $11.00
Super Omega 3-6-9 1200 mg (180 Softgels)
Super Omega 3-6-9 is a blend of Fish, Borage and Organic Flax Seed Oils...$29.99As low as: $22.49
Vitamin D-3 5000 IU (120 Softgels)
Vitamin D-3 5000 IU (bottle of 120 softgels)...$12.99As low as: $9.75
Vitamin D-3 2000 IU (120 Softgels)
Vitamin D-3 2000 IU (bottle of 120)...$8.99As low as: $6.75
Omega 3-6-9- 1000 mg (250 Softgels)
Omega 3-6-9 is a blend of Flax Seed, Evening Primrose, Canola, Black Currant and Pumpkin Seed Oils....$27.99As low as: $20.99
Omega 3-6-9 1000 mg (100 Softgels)
Omega 3-6-9 is a blend of Flax Seed, Evening Primrose, Canola, Black Currant and Pumpkin Seed Oils....$11.99As low as: $8.99
Mega Bust, Breast Enlargement Product
Enhance Breast Fullness, Firmenss and size
Increase Libido
Increase Sex...$29.95As low as: $26.65
CoQ-10 100 mg softgels (bottle of 30)
CoQ-10 100 mg softgbels (bottle of 30)
CoQ-10: Helps maintain heart and Immune Funct...$10.99As low as: $9.00
Wild Rice 1 lb bags
Hand Harvested Minnesota Wild Rice...$8.99As low as: $7.00
Maca 500 mg 10:1 extract capsules
Maca Root powder standardized to a concentration of 10:1 (10 times stronger...$16.99As low as: $14.99
Chaga MushroomPure and Natural Chaga Mushroom Powder...$37.50As low as: $32.50
SuperSize Penis Enlargement Pills
SuperSize Penis Enlargement Pills...$39.99As low as: $35.99
The Herbalshoppe Story
It started with one family seeking to live a healthier life...
For over three generations our family has been dedicated to helping people lead healthy lives. It started in a pharmacy, transformed into a dynamic health foods store and then exploded into an online movement. A lot has changed over the years, but one thing has stayed the same. We are here for you. We are committed to be your supportive source for products and knowledge, to help you on your journey towards happy wellness.Learn More about us


text:
Thunder need to adjust with Westbrook back in the mix
All along, Scott Brooks has told us there's a plan in place for Russell Westbrook.
OK, but Brooks didn't say he was going to stick to it.
Brooks said Westbrook won't play both ends of back-to-back games and also said Westbrook will be limited to no more than 30 minutes, then said no more than 32 minutes.
Must have been the craziness of the regular season that got to Brooks Tuesday night in Dallas, because Brooks changed his mind and ignored the minutes restriction that was supposedly limiting Westbrook, but didn't play Westbrook when he needed to, only when he felt like he had to. The result was an overtime loss to the Mavericks, the second time the Thunder have lost to Dallas in the last nine days.
Tied at the end of regulation, Westbrook didn't start the overtime, suggesting he wouldn't play past the allotted 30 minutes he has been given. But when the Thunder fell behind, Westbrook came into the game it looked like Brooks panicked. By the time Westbrook checked in, the Mavericks were up by seven points and there was just more than 2 minutes to play.
But whether Brooks went back on his word or Westbrook got out past his curfew is not the real problem. The issue with the Thunder, with Westbrook and with the rest of the season has to do with rust.
Oklahoma City just isn't as good when Westbrook doesn't play, and when Westbrook does play, he needs time to adjust and assimilate.
Tuesday was the perfect example.
Westbrook was too fast, played like he had a plane to catch and didn't look sharp, particularly at the beginning of the game. He had five turnovers in the first quarter. By the time he got himself under control, Westbrook was nearing the 30-minute time restriction Brooks has for him.
If Westbrook is healthy, and Brooks and the Thunder organization have said he is, the best thing the team can do is play him. The more he sits, the more time it takes to get him back into the comfort flow of the game. Tuesday showed that. Westbrook started choppy and finished with 23 points on 8-of-18 shooting with eight turnovers and eight assists.
Meanwhile, the Thunder will already be working the injured Thabo Sefolosha and Kendrick Perkins back into the lineup toward the regular season. There's no reason to add another variable, or perhaps complication to what will already be a lot of moving parts.
However, if Westbrook is hurt, despite the fact the Thunder say he isn't, then rest him. Forget about putting some minutes restriction on him that clearly isn't a priority. Sit him. Wait it out. Make sure Westbrook is healthy before the playoffs start.
Instead, OKC and Brooks have tried to do both and Tuesday in Dallas and it looked silly. Not only did Westbrook look out of sorts, he busted his restriction, making Brooks look like he panicked.
Follow Andrew Gilman on Twitter: @andrewgilmanOK


text:
Vol. LXIV, No. 21
Wednesday, May 26, 2010
A forum for Princeton residents to express opinions about local and national issues
Were going to Cape May to stay at Congress Hall for three nights. We plan to take day trips, possibly to Hershey Park, Great Adventure Safari, and Sesame Place. Were going to have a fun filled week!
Rob Carrabba with son Nicolas and daughter Olivia, West Windsor
Were taking our usual vacation up to New England. This year were going to see a Red Sox game. This will be Quinns first game at Fenway Park.
Kim, Kris and son Quinn Ramsay, Princeton
Tiffany: Were going on a cruise. We dont know where were going, were still making plans.
Jessica: I am going to summer camp.
Tiffany Guo, Hillsborough (left)
Were both working all summer to make money before going away to college.
Tori Winogora, Princeton (left)
Im going to California. Im going to be staying near the Hollywood Walk of Fame. Im really hoping, Ill see some celebrities during my vacation.
Jennifer Kellett, Princeton
This summer Im going to go to teen travel camp. Im going to celebrate my birthday. I hope to get a PS3 video game, so Ill be playing with it. I also might go to summer school to get ahead while I can. Im also going to be skateboarding a lot this summer.
Ralph Roberts, Princeton
Town Topics® may be purchased on Wednesday mornings at the following locations: Princeton McCaffreys, Coxs, Kiosk (Palmer Square), Krauszers (State Road), Olives, Speedy Mart (State Road), Wawa (University Place); Hopewell Village Express; Rocky Hill Wawa (Route 518); Pennington Pennington Market.
Copyright© Town Topics®, Inc. 2011.
Contact Us | Masthead | Advertise | Submit | Last Week | Back Issues


text:
< Wuzzah?? >
\ ^__^
\ (oo)\_______
(__)\ )\/\
||----w |
|| ||
A robot with artificial intelligence doing gangstar shit while listening to Die Antwoord. What is not to like?This has the basic plot setup for an action sci-fi movie, so there are not real surprises along the way. You know what is going to happen, which comforts you and lets you sit back and enjoy the ride.Now as two of the main characters are the two people representing the musical group/wonder/phenomenon called Die Antwoord, I could not help to wonder how much of their very original style and music would be included. The answer (pun intended!) is A LOT. Their entire… living space(?)... is decorated in the classic Die Antwoord style, and music is brilliantly included into the movie in several ways. As goes for the characters both Ninja and ¥o-Landi Vi$$er are actually playing a (slightly) more gangster edition of themselves, using the same names even.The take on artificial intelligence where a programmer creates the perfect AI and implements it in a robot is nothing new, but the exciting (and also a bit lame at times) thing here is how the machine's intelligence evolves. In my opinion it is not handled all that well here, but it is still quite interesting to start thinking about. How would a self aware machine start learning and how much would the surrounding environment and persons shape the personality of the machine? The second part regarding replicating that personality is equally interesting, but also not handled that well in this movie. However both topics really starts you thinking about the potential and resulting consequences of artificial intelligence.The implementation of Hugh Jackman as the hardcore aussie ex-soldier turning into the evil culprit is great entertainment. The final showdown is obviously over the top, which is fitting for the genre.If you like (or love) Die Antwoord, like I do, this movie is really recommendable. It is a simple action/sci-fi movie but with a really good integration of a musical group with a very peculiar personality and style. If you just like regular action and sci-fi with a take on robots and artificial intelligence, this could still be something for you. If you dislike Die Antwoord, you might want to steer clear of this movie.


text:
Lauren Andersen
East Longmeadow High Class of 2000
Personal Info
- Name:
- Lauren Andersen
- Graduation Year:
- 2000
Memories of Lauren Andersen
Are you Lauren Andersen?
This page means someone is someone is looking for you. Register for free to let other alumni contact you and more:
- Let others find you
- Contact old friends
- Share photos and memories with other registered alumni
Looking for Lauren Andersen?
This is a placeholder page for Lauren Andersen, which means this person is not currently on this site. We do suggest using the tools below to find Lauren Andersen.
About placeholder profiles
You are visiting the placeholder page for Lauren Andersen. This page is here because someone used our placeholder utility to look for Lauren Andersen. We created this page automatically in hopes Lauren Andersen would find it. If you are not Lauren Andersen, but are an alumni of East Longmeadow High School, register on this site for free now.


text:
Kraft® Easy Mac Cup
Price: approx $1 each cup
Serving: 1 cup, 2.05 oz.
Calories: 220
Fat: 7%, 4.5g
Sodium: 27%, 660mg
Protein: 14%, 7g
Carbs: 15%, 39g
Fiber: 1g
I've been an exclusive Mom Knows 100 Reviewer at SheKnows.com since its inception this past Spring. I recently had the opportunity to sample the new Kraft® Easy Mac Cups. I thought I'd share my review here with my Multiple Blessings readers.
Kraft says: Kraft® Easy Mac Macaroni and Cheese Cups make it easy to enjoy delicious macaroni and cheese anytime. The microwaveable cups cook quickly and are full of creamy, cheesy flavor.
After you remove the plastic lid, you might be surprised to find the foam 2.05 oz. cup about half full of macaroni noodles. Remove the cheese sauce packet and set aside. Proceed to fill the cup about halfway to the fill line with water (be sure to use the recommended time and water level markings on the bowl.) Please follow the instructions carefully, as there is very little room for error. Stir the mixture well and place it in the microwave on HIGH for 3 and a half minutes or until the pasta is tender. When it comes out of the microwave, it will look remarkably unappealing – there looks to be way too much water in there and you might have some weird bubbles. Disregard. DO NOT DRAIN. Open the cheese mix packet and dump it in, then stir-stir-stir for a minute or two. The cheesy powder is a bit clumpy and you have to really encourage it to mix with the watery noodles, but stick with it and eventually it will blend. It does thicken a bit upon standing. Once it's done, it tastes pretty much like packaged macaroni and cheese, if done correctly. . Mind you; this is a pretty small cup, about the size of a deli cup of soup, but you'll find that it's warm and a filling snack/fairly decent lunch entree. I rounded it out with some cheese and crackers (yes, I know, cheese on cheese) that I'd had stashed in the cupboard-- and it was a perfectly sized lunch. On its own, this probably wouldn't be quite enough for a fully satisfying meal, but it's definitely enough to get you through in a pinch until you can consume a real meal. The current available flavors, Original Cheese, Triple Cheese, Alfredo and Bacon. Yes, Bacon, but that's not as good, too tangy and salty for my taste. You really don't need to mess with a classic, so my fave was the Original and Triple Cheese flavors.
My kids love these for afternoon snacks when they get home from school, or between lunch and dinner. Even my 9 year olds can make them without adult supervision. Most of the time I'll add a touch of margarine, or cream cheese to make it creamier – I loved the suggestion of adding tuna – my kids love it. Maybe even throw in a tablespoon of frozen peas too….mac, tuna, and peas--great combo!
Given my first prep faux pas, I must admit that I was fairly satisfied with Kraft's® Easy Mac microwave cups. I know that they create waste and cost too much, but they do deliver a decent amount of salty, cheesy macaroni product. Being rather frugal minded, I'd probably only buy them if they were drastically discounted at my local grocery store. Otherwise, for my family--the convenience doesn't justify the expense.
*I received a product sample for this review, but no monetary compensation. The views and opinions expressed in this post are my own.*


text:
While worldwide energy consumption continues to grow exponentially, the supplies of nonrenewable resources like oil and natural gas unfortunately continue to dwindle. Consequently, many people are beginning to advocate renewable energy as an alternative to fossil fuels. One particular method of obtaining petroleum and gas, known as fracking, has become an especially hot topic among energy enthusiasts.
Fracking (short for hydraulic fracturing) is the process of shooting a highly pressurized liquid mixture into a pre-drilled hole in the earth to create small cracks in the bedrock. These cracks give us access to fuels like natural gas and petroleum that we would otherwise not be able to harvest.
There are a few reasons why fracking is getting such a bad rap. The primary reason is because the injected liquid is infused with harmful chemicals, some of which are even known carcinogens. Shooting this liquid into the earth can lead to groundwater contamination. Another aspect that people are taking issue with is the enormous amount of water used in the liquid mixture, water that could instead be used for drinking, bathing, or irrigation.
Still, fracking clearly has its benefits. The oil and gas we've been able to collect through the process has significantly boosted domestic oil production, leading to a reduction in gas prices. It also allows us to generate electricity with about half the CO2 emissions as generation using coal.
So, if fracking is so controversial, why don't we just make the switch to renewable energy? Simply stated, it would cost way too much. Energy generators like solar panels, windmills, and dams are all expensive to install and maintain. Another big issue is that they're not very reliable since they all depend on weather. And unfortunately, even when the sun is shining, the wind is blowing, and the water is flowing, they're still pretty inefficient.
Despite these obstacles, the benefits of renewable energy have convinced many people that it's worth the extra cost. Possibly the most attractive feature is that it doesn't pollute the environment; it's as clean and environmentally friendly as power production can get. And, unlike fossil fuels, we never have to worry about these sources disappearing. Renewable energy is especially advantageous in regions where there's no access to a power grid, as is the case in many third world countries.
When it comes right down to it, the truth is that neither fracking nor renewable sources by themselves can produce enough energy to satisfy the needs of our power hungry world. Since fossil fuel supplies are finite, we do know that there will come a day where we'll have to depend on renewable energy. Right now, however, we depend on both.


text:
Hello again, faithful readers! Today's post is a quickie to talk about a couple of recent developments.
First, we have new offers from Linden Lab for existing and prospective Premium members. For all Premium members, there's a new Premium Gift. It's a Pirate Airship vehicle, with plenty of sit positions for captain and crew, and firing guns. That's nice...but it's also very primmy, with a Land Impact value of 502. Don't sail into any almost-full parcels, matey!
LL is also repeating their periodic offer of 50% off on a new quarterly Premium membership. Note that this applies only to NEW Premium members. You can't cancel your current membership, then sign up again and get the discount. It only applies to the FIRST quarter. After that, you pay the regular quarterly Premium fees. What all this boils down to is that you actually get a better deal if you simply sign up for the annual plan at $72 per year. But do be aware that LL never gives refunds. If you decide you want to downgrade back to Basic, you will NOT get a refund of unused time on your membership! You're locked into whatever period you select until the end of the billing cycle, whether that is monthly, quarterly, or annually.
The Official Blog Post: http://community.secondlife.com/t5/Featured-News/Limited-Time-Offer-Save-50-on-Premium-Membership-and-Get-the-New/ba-p/2779820
Everything You Should Know About Premium Membership: http://community.secondlife.com/t5/English-Knowledge-Base/Premium-membership/ta-p/1054477
Last, we have a New Bug. Some people who use PayPal as their payment method are finding themselves unable to log in, getting the message "Unable to Connect to a Simulator." If this sounds like you, first go to your Account page and remove PayPal as your payment method. Then log in. After you've logged in successfully, you MAY be able to add PayPal back to your account. Read more about this bug here: https://jira.secondlife.com/browse/BUG-6735?
Oh, and one last tidbit: N-Core is retiring all their old sculpty shoes, and is offering them at 60% off for a limited time. There's not a thing wrong with using sculpties for shoes instead of Mesh, so this is a great time to save some money on some of the cutest shoes in Second Life.


text:
Michael Sommer, leader of the DGB trade union federation, called the latest wave of sackings a "declaration of war" against Germany's workers. "Social unrest can no longer be ruled out," he said.
Gesine Swann, presidential candidate for the Social Democrats, said "the mood could turn explosive" over the next three months unless the government takes drastic action.
While authorities have belatedly agreed to create a "bad bank" to absorb toxic loans and stabilise the credit system, further financial troubles are almost certainly in the pipeline.
Swiss risk advisers Independent Credit View said a "second wave" of debt stress is likely to hit the UK and Europe this year as the turmoil moves from mortgage securities to old-fashioned bank loans. A detailed "stress test" of 17 lenders worldwide found that European banks have much lower reserve cushions than US banks, leaving them acutely vulnerable to the coming phase of rising defaults. "The biggest risk is in Europe," said Peter Jeggli, Credit View's founder.
Deutsche Bank has reserves to cover a default rate of 0.7pc, against non-performing assets (NPAs) of 1.67pc; RBS has 1.23pc against NPAs of 2.43pc, and Credit Agricole has 2.63pc against NPAs 3.64pc. None have put aside enough money.
By contrast, Citigroup has reserves of 4pc against NPAs of 3.22pc; and JP Morgan has 3.11pc against NPAs of 1.95pc.
"The Americans are ahead of the curve. European banks are exposed to US commercial real estate and to problems in Eastern Europe and Spain, where the situation is turning dramatic. We think the Spanish savings banks are basically bust and will need a government bail-out," said Mr Jeggli.
The IMF said European banks have so far written down $154bn (£105bn) of bad debts, or just 17pc of likely losses of $900bn by 2010. US banks have written down $510bn, 48pc of the expected damage.
Analysts say America's quicker response has given the impression that US banks are in worse shape, but this is a matter of timing and "transparency illusion". Europe risks repeating the errors made by Japan in the 1990s when banks concealed losses, delaying a recovery.
Europe's banks are exposed to a hydra-headed set of bubbles. They not only face heavy losses from US property, they also face collapsing credit booms in their own backyard and fallout from high levels of corporate debt in the eurozone.
Mr Jeggli said the financial crisis was "front-loaded" in the Anglo-Saxon countries and Switzerland because their banks invested heavily in credit securities. As tradeable instruments, these suffered a cliff-edge fall when trouble began, forcing harsh write-downs under mark-to-market rules.
It takes longer for damage to surface with Europe's traditional bank loans, which buckle later in the cycle as defaults rise. The ferocity of Europe's recession leaves no doubt that losses will be huge this time.


text:
Monday - Saturday 08:00-17:00
Sunday - CLOSED
When it comes to your body you ought to be very careful. There are several clinics that will promise to provide you the best at quite less price but there is a reason they are able to do that. They perform the surgery through general surgeon where as Harley Body Clinic uses Cosmetic Surgeon for Cosmetic Procedures. A specialist does his job far better than a generalist.
Be it Invasive or Non-Invasive procedure such as Vaser Liposuction, a consultation before surgery is a must. In Harley Body Clinic your consultation will always be with a surgeon. A Cosmetic Surgeon is well trained both in basic and advanced procedures. For instance: A patient may not always be suitable for Vaser Lipo, but be suitable for traditional liposuction. In such cases our Cosmetic surgeon would be able to identify which is best for the client as he is trained in both the procedures.
Harley body clinic is located in the famous medical district of the world, Harley Street. Through investment in next generation equipments and technologies we aim to keep ourselves a step ahead of the rest. Harley Body Clinic has the latest Vaser Liposuction system that can remove large volumes of fat with minimal pain and bruising. In the market, we offer the best prices. With lots of vaser Liposuction done, we are capable to cut down the cost by spreading the overhead.
Selecting the right clinic for undergoing vaser liposuction or vaser lipo is very important to get the right kind of treatment. There are few ways to judge, which is the right clinic for you:
– The first thing you need to do is to make a list of all the clinics offering vaser Lipo and call them to receive more and more information about the entire procedure.
– A good vaser liposuction clinic should conduct a full examination of your body as well as your medical history.
– The skill of doctors is equally important to determine a good clinic. The more a doctor practices, the more experience he gains. You can go through newspapers and journals to get hold of names of famous and experienced doctors.
– Your list must also include the point of 'after care programmes'. Clinics which offer these kinds of programmes are great options.
At Harley Body Clinic we offer the best services at affordable prices. Being a professional liposuction clinic we usually offer our prospective clients with a consultation session to clarify his needs and suggests him/her the suitable packages. We also suggest suitable diets and exercise regime to clients so that they can get the best results from vaser treatments and retain the shape for long. It is also commonplace to see vaser lipo clinics offering 'after care programs'.
Reviews of the Harley Body Clinic
4.7 out of 5 stars based on patient reviews


text:
Do you love those sweet Little turquoise blue jars that we see all over the internet? I know I do.. They speak to us .. of simpler times of days gone by.. My Charming Hand Crafted Hand painted Chalkboards are made from a lightweight hardboard and strung with jute for hanging. I use premium materials and seal the artwork with a polyurethane finish. This chalkboard measures 24" x 24" and has nice vintage looking rounded corners. Simple soft sculpt frame finished with a bead paint detail. Bright fun artwork with a washable chalkboard surface.
Daisy's From The Garden
Rununculus and Lavender


text:
Latest News
Results from the County Antrim Championships attached.
Drum Major's dress time at Glenarm is 12.30 p.m.
The draw for the County Antrim Championships is now online and can be accessed by clicking here.
Spectator concession tickets priced £10.00 for the County Antrim Championships at Glenarm on the 14th of July will be on sale at the registration tent at the All Ireland Championships in New Ross this Saturday. If spectator tickets aren't purchased in advance they will cost £20.00 on the day of the County Antrim Championships at Glenarm.
Bands will also be issued with wristbands for Glenarm this Saturday.
- On behalf of the County Antrim Section we hope that everyone enjoyed the Festival & Pipe Band Championships yesterday in the lovely setting once again in Glenarm Castle . The weather started of cool and windy in the morning and got slightly better as the day progressed, but as the finale got closer the weather turned for the worst and we had to make some late changes. Unfortunately we had to cancel our new event for the senior Drum majors of Tossing the mace over the high bar ,but weather conditions hindered this great event
- The section would like to take this opportunity and thank our sponsors for this event All Things Tartan & The Quiet Man Irish Whiskey.We would like to thank everyone who helped in any way who made these championships successful along side the Dalradia Festival .
- The section would like to thank all bands ,drum majors,Stewart's,judges,caterers,i personally could not thank the bands and drum majors and judges enough for their support ,and a special thanks to Paula for her help ,a big thanks also to the main man on the day our compere Gary Wilson 👌👌👌👌👍👍👍👍
- We once again wish all bands,drum majors all the best for the rest of the season and that they bring silverware back from the remaining Major Championships
Alistair McCleery
Please see attached results from today's Co.Antrim Championships at the Dalriada Festival in Glenarm.
Today seen the lauch of the Dalradia Festival & The County Antrim Pipe Band &Drum Major Championships which will be held on 15th&16th July once again in Glenarm Castle.
This year the festival is going to be bigger and better according to organisers , and the County Antrim section are working close we with everyone .This year the section are hopefully getting sponsorship to host something special for the Senior Drum Majors .(watch this space for more info)
For all you campers and Motorhome personnel can I ask you to apply as quickly as possible as this was also launched today ,simply go to Dalradia Festival page and follow link to get camping passes.,everyone can see what other great attractions are coming this year ...if you like Nathan Carter or Peppa Pig come along as there something for everyone.
Watch this space for more info .......
Photos of the County Antrim Championships are available to view by clicking here


text:
Located overlooking the glittering Victoria Harbour, The Mandarin Oriental hotel, is the perfect and ultimate luxury hotel on the perfect location. From the moment you enter you will be treated like a royal, service truly is impeccable.
Rooms are so well furnished and have all the amenities you could desire (even Hermes toiletries). While booking, keep in mind that rooms ending with number 1, for example 901 or 1601 all have amazing views over not only Statue Square but also over the fabulous harbour.
The hotel is very well known for its amazing Spa. This three-story Mandarin Spa, is one of only 18 spas in the world to be awarded five stars by the prestigious Forbes Travel Guide.
There's a small swimming pool and a well equipped, large gym.
After a day of sightseeing, go for drinks to the rooftop M Bar where they serve cocktails and Cantonese tapas with the best view in the house.
Address: 5 Connaught Road, Central Hong Kong
Telephone number: +852 2522 0111
Website: www.mandarinoriental.com/hongkong


text:
A very fast, easy recipe sure to help the mid-day hunger.
1 Can Pork & Beans
1 Can Black Eyed Peas
1/4 c. Brown Sugar
1 Small Can Tomato Sauce
1 Can Kidney Beans
1 lb. Ground Beef
1/8 c. Mustard
Brown ground beef. Pour everything else in the pot and simmer for an hour. Enjoy!


text:
South African miner Metorex said on Monday that it had still received no firm offer from any party other than Brazil's Vale, which has made a $1.1 billion offer for it.
Metorex Mining News
Vale could square off against Chinese miner for Metorex
Market sources indicate a serious Chinese contender has finally decided to make a bid for Metorex, in opposition to Vale's $1.1bn cash offer for the South African company. There has been speculation in the market over such a development since the Vale bid was announced in mid-April, with Jinchuan Mining singled out as the most likely bidder. Jinchuan is the company which now controls Wesizwe Platinum after heading up a Chinese consortium which paid some $940m for 51% of Wesizwe.
We have a duty to consider any serious offer – Metorex
South African miner Metorex (MTXJ.J: Quote) said on Monday that if there were any other serious offers to acquire it aside from one launched by Brazil's Vale (VALE5.SA: Quote) it would have to consider them. "If there are other serious and 'firm' offers for Metorex, the company has a duty to consider them and will of course consider any such offers in the best interests of its shareholders," Metorex CEO Terence Goodlace said in an e-mailed response to questions submitted by Reuters.
Vale bids $1.13bn for Metorex
Brazil's Vale (VALE5.SA: Quote), the world's largest producer of iron ore, has made an offer to acquire South African miner Metorex Ltd (MTXJ.J: Quote) for 7.5 billion rand ($1.13 billion), the two companies said on Friday. "Under the terms of the offer, if implemented, the Metorex shareholders will receive a cash consideration of 7.35 rand per share," the companies said in a joint statement.
MDM awarded Kinsenda copper project BFS in the DRC
Potentially one of the DRC Copperbelt's richest copper mines, Kinsenda is the subject of a Bankable Feasibility Study commissioned by Metorex and to be undertaken by MDM Engineering Group. Read more


text:
About Cool Porygon
Hi, I'm Cool Porygon. Ive been a Pokemon fan for about years, I still love it. I play the trading card game, video games, and the trading figure game competitively. I have come 2nd in pre releases 3 yeas running. I also placed 10 in 2007 world champion chip last chance qualifier. Almost made it in. My favorite Pokemon is shocking shedninja. if you have any questions, comments, or concerns please contact me either by the forum or you can IM me. My screen name is redrobbin200. or e-mail me at firstname.lastname@example.com. Thanks visit again. Sincerely Cool Porygon


text:
The AutoScan Collaborative RoboGauge combines Perceptron's Helix 3D laser scanning sensor with industrial robot technology to create a standardized gauging cell.
A rigid machine base holds both the robot and part fixture with translucent side panels with light-up visual color status indication. The RoboGauge perimeter is monitored using integrated laser scanners, using the diffused reflection of emitted IR laser light to create a 2D programmable detection safety field.
The Helix scanner incorporates a microelectromechanical (MEMS) device that allows for laser line quality, density, length and orientation characteristics to be programmable, eliminating the robot's need to move the sensor while scanning.
The RoboGauge provides a highly flexible automated shop-floor metrology solution capable of measuring sheet metal, fabrications, moldings and cast parts. RoboGauge can also be used in comparative or absolute inspection mode.
Click here to see other Collaborative Solutions


text:
The Circus: An Animal's Life Behind the Red Curtain
What do we picture when we think of the circus? Beautiful tents with bright colors, hilarious clowns (maybe not so hilarious for some), the amazing acrobats and trapeze stunts, and of course to make the experience complete there has to be the exotic animals and the 'wonderful' tricks they all perform. This article is for you so see the not-so-wonderful side of the circus: how exactly do the animals learn these fantastic tricks, how they obtain their animals, and the overall life of a typical animal in the circus.
History of the Circus
The very first circus that was brought to America in 1793 by Englishman John Bill Ricketts, right after the country was founded. The circus back in that time was something absolutely fantastical! An event that was truly spectacular and a definitely a 'must-see'. Back in those days, the circus provided people with a first look at new and strange inventions and contraptions, entertainment and danger, bizarre looking clowns, exotic animals with their exotic trainers from distant lands.
Ricketts incorporated several of his acts from Phillip Ashley who started the first real circus in England. It was Ashley who created the idea of a round stage, and the universal circus music. Ricketts stunts involved several famous daredevil aerobatics, riding on dangerous animals, and he was soon known as the Master-Rider with stunts such as the Flying Mercury and Egyptian Pyramids that soon became his trademark.
Yet in 1979 Ricketts fell into financial ruin and his performing days came to an end; but not without leaving a lasting impression on American audiences everywhere. Modern-day circus's such as Cirque de Soleil still perform several of Ricketts acts today.
Circus Animals
The tricks the animals are able to perform at the circus are all amazing, but amazing or not, it is unnatural and cruel. It is not natural for an elephant to sit on a chair, stand on their head, crawl, twirl, or mount on top of each other. Yet these are some of the most common tricks performed at several circuses. David Hancock, former director of the Woodland Park Zoo in Seattle, states "when circuses portray animals as freaks and curiosities, devoid of context or dignity, circuses are perpetuating outdated attitudes. Wild animals in the circus are reduced to mere caricatures of their kind, exhibited just for financial gain. In this way, they corrupt our children, promoting the notion that exploitation and degradation is acceptable, even brave or funny."
Here is an inside look at exactly how animal handlers and trainers teach the animals how to perform these acts using tools such as whips, sticks, electric prods and bull-hooks.
The most common tool used in teaching animal's tricks is the ankus, or bull-hook, which is a long rod, and in design is meant to cause severe pain. At first glance an elephant's skin may look very tough, but in truth it is as sensitive as a humans. The bull-hook is used to create fear and knowledge of pain if the animal refuses to cooperate, so that they will perform the tricks accurately in front of the audience when the hook cannot be used. This tool bruises, punctures and tears at the animal's skin very easily and very often. Former employees of the famous Barnum and Bailey's Circus openly claim that they always have bags of topsoil handy so they can cover the animal's wounds and cuts before show time. The bull-hook is used even on the baby elephants when they first arrive, as you can see above.
Ringing Bros. may state that "our training methods are based on continual interaction with our animals, touch and words of praise and food rewards," when in reality it is nothing of the sort. Video footage taken between 2001 and 2006 shows animal aggressively hooked, and elephants that had gone mad and are still forced to perform and travel to different venues. Several employees of Ringling Bros. either quit or were fired from the circus due to their noncompliance with the training methods and describe regular beatings and abuse towards elephants, horses, camels and zebras.
Another false claim by Ringling Bros. is their attempt to save endangered Asian elephants by placing them in their circus, but records show that in 1990, of the approximately 66 elephants in their care, 57 were captured from the wild and at least 24 elephants have died since 1992. The health and behavioral problems of their elephant's show that it would be impossible to rehabilitate them and get them ready to be released back into the wild; they would not be able to survive. Ringling has also been unsuccessful at breeding more elephants than it has imported and captured for their traveling show, and as a result their elephants are dying at a faster rate than they are breeding.
Beside the routine cruelty methods, the US Department of Agriculture (USDA) reports show that Ringling Bros. have been given several citations that greatly impact animal welfare. One example is in 2003 where they were fined three times for not providing adequate veterinary care to a disabled elephant, an elephant with a large swelling on its leg, and a camel with several bloody wounds.
In 2006, the circus troupe was cited again for causing physical harm, behavioral stress, trauma, improper handling of dangerous creatures, improper enclosure, and discomfort to two baby elephants who suffered abrasions and deep cuts when they ran amok in an arena in Puerto Rico. Ringling Bros. was also forced to pay a $20,000 fine towards the USDA for charges for failing to provide veterinary care to a sick baby elephant that shortly died after he was forced to perform.
Yet Ringling Bros. obstinately states "our staff are experts in their field," when in actuality they continue to hire inexperienced people, some straight from homeless shelters and allow them to work around animals. Several of their employees have been known to have serious criminal backgrounds such as child predators, sex offenders, and violent criminals.
One example is Thomas Allen Riccio that worked as a clown, 'Spanky', for Ringling Bros. was charged with 10 accounts of third-degree sexual exploitation of a minor on May 25th, 2004. Officials reported finding 2,000 pictures on Riccio's computer, which was kept in his room on the circus train, containing girls as young as five-years old engaging in sexual activities with adults. The complete list of citations and other problems several circuses have committed can be viewed here.
The living conditions for circus animals are no better. When not chained down, most elephants are reported to be confined in barns and small outdoor padlocks. Their facility in Williston, Florida, where it is referred to as their 'animal retirement home,' has several elephants exposed or infected with Tuberculosis (TB). Two elephants at their breeding center in September of 2006 were also tested positive for TB and three more were pulled off the road due to their exposure to the diseased elephants.
To end this article properly, I've submitted a video showing a few baby elephants born at Barnum and Bailey's circus so you may see the neglect for yourself. Yes, it IS a P.E.T.A. video, but don't let the name scare you; it is not as notoriously graphic as their other footage of animal cruelty. Narrated by actress Kathy Najimi (Rat Race,Wedding Planner); she gives a detailed description of baby elephants raised in a typical circuses and how they were meant to live naturally in the wild.
Animal Friendly Circuses!
7 Fingers
Tel.: 514-521-4477
E-Mail: firstname.lastname@example.com
Web: les7doigtsdelamain.com Bindlestiff Family Cirkus
P.O. Box 1917
New York, NY 10009
Tel.: 212-726-1935
E-Mail: firstname.lastname@example.com
Web: www.bindlestiff.org
3700 S. Four Mile Run
Arlington, VA 22206
Tel.: 703-683-5040
E-Mail: firstname.lastname@example.com
of the Kids
926 Waverly Rd.
Tallahassee, FL 32312
Tel.: 917-208-6341
E-Mail: email@example.com
Web: circusofthekids.com
du Soleil
8400 Second Ave.
Montreal, Québec Canada
Tel.: 514-722-2324
E-Mail: firstname.lastname@example.com
Web: cirquedusoleil.com
4230 rue Hogan
Montréal, Québec
Tel.: 514-596-3838
E-Mail: firstname.lastname@example.com
Web: cirque-eloize.com
P.O. Box 53017
Succursale Canardière, Québec G1K 5K3
Tel.: 418-661-1961
E-Mail: email@example.com
Web: cirqueeos.qc.ca
37 rue Battant
Besancon 25000
Tel.: 33-3-81-81-38-80
E-Mail: email@example.com
Web: cirqueplume.com
Cirque San Jose
634 N. Eighth St. San Jose, CA 94112
Tel.: 408-929-0678
E-Mail: email@example.com
Street Circus
P.O. Box 621004
San Diego, CA 92162
Tel.: 619-235-9756
E-Mail: email@example.com
Web: fernstreetcircus.org
High Circus
FSU Circus
Tallahassee, FL 32306-3064
Tel.: 850-644-4874
E-Mail: email@example.com
Web: fsu.edu/~circus/
& Velocity Circus Troupe
225 San Leandro Way
San Francisco, CA 94127
Tel.: 415-242-4196
E-Mail: email@example.com
Web: gregangelo.com
Hawaii's Volcano Circus
Educational Nonprofit Organizations
RR 2, Box 4524
Pahoa, Hawaii, 96778 USA
Tel./Fax: 808-965-8756
E-Mail: email@example.com
Web: http://hiccupcircus.com
Circus of China
c/o Management One, LLC
7380 Sand Lake Rd., Ste. 350
Orlando, FL 32819
Tel.: 321-281-4000
E-Mail: firstname.lastname@example.com
Web: imperialcircus.com
621 S.W. First Ave.
Ocala, FL 34474
International Circus
C/o Xentel DM
609 14th St. N.W., Ste. 300
Calgary, Alberta T2N 2A1
Web: www.Mexicancircus.com
Neil Goldberg's Cirque
Cirque Productions
Variety Arts Management
3803 N. 29th Ave.
Hollywood, FL 33020
Tel.: 954-922-0888
E-Mail: email@example.com
Web: cirqueproductions.com
Pickle Circus
755 Frederick St.
San Francisco, CA 94117
Tel.: 415-759-8123
E-Mail: email@example.com
Web: circuscenter.org
Shanghai Circus
P.O. Box 2205
Branson, MO 65615
Tel.: 417-335-2000
E-Mail: email@example.com
Web: acrobatsofchina.com
American Kids Circus
The Brad Simon Organization, Inc.
122 E. 57th St.
New York, NY 10022
Tel.: 212-980-5920, ext. 12
E-Mail: firstname.lastname@example.com
Circus Theatre
19 Wansfell Rd.
South Yorkshire
Tel.: 44-0-114-256-0962
E-Mail: firstname.lastname@example.com
Web: swampcircus.com
its really sad watching the people smacking the elephant. it cruelty to animals..Thank you for your comment
Maryland Avenue,city,Pinellas,Florida,USA
its really sad watching the people smacking the elephant. it cruelty to animals. how dare you?
This article is full of facts thanx soooo much for the info. AND to all those circuses that use animals, wtf and SAME ON YOU
Thank you Dear! Animals need our love and supervision but never cruelty. Same as people! There is no place for cruelty. God bless!
Your article was filled with so many facts that are unfortunately very true. I feel the same way as you regarding the animal circuses. Thank you so much for standing up for the animals!!! Too many people do not know what the animals have to go through behind the scenes. Thank you again!


text:
Isle of the Dead (2016) description:
Isle of the Dead – present to your attention the film from the producer of the famous television series Nation Z / Z Nation. The film tells the story of military special squad, which was sent to the island in the Pacific on a mission to find out the cause of the disappearance of the previous command. They will not only find the missing soldiers, but also to understand the reason of the origin of the virus turns people into bloodthirsty zombies.
Duration: 1:24:31
Starring: Joseph Lawrence, Maryse Ouellet Mizanin, DS Douglas, Josh Crotty, Duch-Barr Johnson, Eric Blossom, Todd Cattell


text:
Code: Select all
The programme is well worth a listen via BBC iPlayer.That's rather a depressing question.
Certainly, in The UK and, I think, in America there's been a tendency for the liturgy to have become associated with a particular moment in folk music; so we sing in church the kind of music that we would never dream of listening to at home or anywhere else. I think there's been a radical impoverishment and a loss of the sense of the numinous. The traditional function of music – to lift the spirit and to provide a standard of excellence that transcends the 'everyday' is hard to recover.
The theory behind it often included the idea that everybody ought to participate and so you got church orchestras together in which people played recorders and triangles and guitars and so on, and that it was better that there should be participatory music than that there should be excellent music.


text:
We are pleased to announce the official release of firmware version 1.7, that adds many great new features to our award-winning Wireless Collaboration Solutions!
To offer additional peace of mind to users, we have created a more secure VIA login process. To enjoy this high security level, please update all client applications on your PC, MAC, and iOS or Android device.
Please note: If you are still running an older version of the client application you will be unable to connect to the VIA gateway while running the new 1.7 firmware.
Firmware Update 1.7 – Notable Features:
• iOS Mirroring for VIA Connect PRO
o Mirror your iOS devices on both VIA Collage & now the VIA Connect PRO, without the need to download any additional software.
• DHCP Support for VIA Connect PRO
• 4K UHD Support for VIA Collage
• DND – Do Not Disturb Mode
o Very Simple, On-the-Fly moderator support – enable DND and no one can interrupt your presentation until you disable it.
Firmware Update 1.7 – Additional Features:
• Easy Moderator Mode
o Enable support for a moderator / standard-user type environment without the need to reboot.
• File Sharing between All Devices
o File sharing is now supported between all PC's and mobile devices.
• Chat ON/OFF
o Moderators can disable chat at any point during a session.
• Custom button/icon for a URL link on the Collage
o Create shortcuts to your favorite websites and embed them right in the VIA Collage user interface.
• Enhanced Security
• Thumbnail View for VIA Collage
o New layout for displaying multiple presenters' content on the main display. Thumbnail view enables a "virtual last-in" solution showing the last presenter's content full screen while providing active thumbnail views of the other presenters' screens.
• Additional Languages for International Integration
o Japanese, Spanish, Chinese, Polish, Russian, and German.
Note: Those using the VIA application on their smartphone, tablet or iPad have been automatically updated to the newest version of the VIA application. To continue to use these BYOD devices, you will be required to update your VIA product firmware to version 1.7, using the links provided below.
You will need the serial number of your VIA product to download the new firmware. If you have any questions, please contact our technical support department at 888-275-6311.


text:
What is meant by the term "anarchism" as used by Christian and State?
The popular picture of an anarchist, is one who throws bombs in the streets, recognizes no external authority, and is bent on unleashing the maximum chaos possible. The biblical picture of an anarchist is best exemplified in the teachings of Jesus. The story? The good Samaritan (Luke 10:29-37). In a case of need, he took direct action to help a victim of violence—without forcing others to pay for it. The Samaritan's actions were quite ordered. True anarchism is the active embrace of responsibility-taking, godly interaction with others, the rejection of power-seeking over others, and servanthood. It means to voluntarily seek justice and mercy.
The opposite of anarchism is not order, but statism. Statism is the creation of an essentially fictional collective entity. Those few thousands of persons who actually constitute it, as well as those who choose to accept the orders handed down, raise up armies, maim, murder, steal property and redistribute. They participate in lordship over others and empire. God's name is often invoked as He who has appointed the state. Persons are said to be absolved of any actions taken while under the orders of agents of the state. Meanwhile, the state has no real existence, no virtue, no guilt. Agents of the state can put a gun in your hand and order you to murder, but you pull the trigger or not. You remain—always—personally responsible for your actions.