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The Oscars are over, but the fashion analysis has just begun. Some actresses — like Gwenyth Paltrow, Michelle Williams and Viola Davis — have landed firmly on the best-dressed list. For others, like Jessica Chastain and Angelina Jolie, the jury's still out.
Either way: As much as Oscar-watchers covet the gowns they see on the red carpet runway, they're not entirely practical for the rest of us. That's where our Polyvore style challenge comes in: We want you to adapt your favorite red-carpet look from the Academy Awards into an outfit that would make a regular girl look like a movie star.
The challenge is part of our ongoing Oscars Remix: Washington Post Polyvore Style Search, where we'll select finalists to serve as guest style correspondents here in The Style Blog. To play, create a Polyvore collage featuring a less glitzy outfit inspired by one of this year's best Oscar dresses. Remember, your ensemble should reflect a sense of the chosen individual's personal style as well your own creativity and eye for fashion.
Enter by clicking on the image below to visit the contest page on Polyvore.com. You can read the official contest rules here.
More on the 2012 Academy Awards:
'The Artist' wins best picture; Streep takes home third career Oscar
TV review: Oscar's wishful thinking
At the Governors Ball: Meryl Streep, Billy Crystal and more
Oscars 2012: The comprehensive Academy Awards recap


text:
Art expands a home's horizons, and when selecting what to add to your house, art enthusiasts say to go with what you love
Story by Carlo Wolff
Photography by Michael C. Butz
In his play, "Back to Methuselah," George Bernard Shaw may have characterized the personal value of art best: "You use a glass mirror to see your face; you use works of art to see your soul," one character tells another.
That complicated maxim resonates with gallery owners, homeowners and art collectors alike. Seems no matter your position in the art field, art nurtures the soul — and enhances the home.
Take the views of Sue Cahn and Jacquie Meyerson, who, with partner Howard Koverman, own Pennello Gallery in Cleveland's Little Italy district. Pennello, which is Italian for "paint brush," sells conventional, even functional art, along with imaginative Judaica, like portable, chain-link menorahs, silver dreidels and ornamental silver mezuzahs. The window display in the wraparound storefront Pennello has occupied for the past 10 years is inviting indeed.
"Art makes our home a home," says Cahn. "It adds color, it adds focal points, it adds interest, it adds beauty." Meyerson, who often caps Cahn's sentences (and vice versa), says "it can add serenity."
Art can occupy its own space; it can be standalone, Cahn suggests.
"A lot of people don't understand that it doesn't have to match the furniture," she says. "You purchase art because you love it." Is art therapeutic? "Extremely. You sit in your house and look around the room and it can be very calming."
Meyerson elaborates, "Every piece of art will evoke emotions that a viewer brings to the piece." It can be thought-provoking, too, like Cynthia Polster's "Women of Significance" series of voluptuous, earthy figures.
"It also brings comedy into the home," says Cahn. "Many of our pieces are very whimsical."
Particularly amusing examples are papier mâché sculptures of a weightlifter in full extension and of a reporter with cameras around his waist, pencil behind his ear (how retro). They're made by artist Naava Naslavsky, an Israeli native and a microbiology researcher who lives in Omaha. They bring a smile to one's face.
The gallery also offers singular bridal gifts "that will carry a couple through their lives," says Cahn. "It's not just dishes." What Pennello's customers — many connected to the nearby Cleveland Clinic, University Hospitals and Case Western Reserve University — seek is "something different and unusual that's handmade, not made in a factory in China," adds Meyerson. All Pennello's offerings are made in the U.S., Canada or Israel.
Not only does art express the artist, it also expresses the person who buys it and displays it, says Steve Hartman, who, along with Karen Tscherne, owns Contessa Gallery in Lyndhurst.
"For many people, art is the highest form of personal communication of what they value, what influences them, how it makes people feel," he says. "To surround yourself with things that are stimulating you, whether it's a physical response, emotional response or spiritual response, I think is something that affects people at their truest core."
Hartman, whose Legacy Village gallery is oriented toward collectors like himself, suggests that while art can be relaxing, it also can increase productivity, leading art lovers to "think in a different way to enhance their brain waves to activate creativity." Each work of art can elicit a different response, "some more emotional, some more intellectual," he says. And every owner "has a unique relationship with each piece of art."
"I think that, again, art is very possibly the highest form of personal expression, and for that reason, it really helps people to connect with the world and themselves," says Hartman, who launched Contessa in 1999. "Some artists and some people look at art almost as seeing a self-portrait in a way even if it's something abstract. … Some people see a self-portrait in every work with which they engage because everybody sees, feels and reacts differently."
So art is both mirror and self-validation? Yes, says Hartman, "because engaging art is what it is like to express oneself and to get inside oneself as to how it makes one feel about the world. That's why it is that mirror and self-portrait."
Art also is about surrounding yourself with unique works of the imagination. Let's visit a home that's a virtual gallery in itself.
Mike and Annie Belkin collect art, particularly contemporary art glass. Their home in rural Geauga County is awash with glass, paintings and sculpture on all three floors, from the whimsical ceramics Annie favors to the glass Mike has been amassing — and the couple have donated to museums — over the past nearly 50 years.
Mike Belkin, who may be known best for Belkin Productions, the rock 'n' roll juggernaut he founded with his brother, Jules, in 1966, explained what art means to him and how it enhances his feeling of home. Art has characterized his home in Russell Township since he moved there in the mid-'70s.
Over those decades, Belkin has acquired striking modern, and deeply artistic, furniture; limited-edition books on art and artists, rock 'n' roll and popular culture; watches; and his latest craze, coins.
Belkin began by collecting antique paperweights and beaded purses, branching out into Tiffany glass, modern paintings and drawings and, most importantly, contemporary art glass by the likes of Dale Chihuly, Steven Weinberg, William Carlson and Paul Stankard. An old-fashioned patron of the arts, he has commissioned work by some of those artists.
"Beauty is very important," Belkin says, "because I like it, I like beautiful things, and I like the craftsmanship involved, I appreciate that." As he walks through his house, he points to a Weinberg that's part prism, part wheel, altogether magic. "I love art, especially glass art," Belkin says. "I appreciate the beauty and beautiful objects. People who create, whether it be art or music, people who are creative and do all these things that I can't do."
The Belkins often acquire art in their travels, attending seminal shows such as Art Basel in Miami. They also often become friends with artists they particularly enjoy.
What advice would Belkin give the beginning art collector? Go with your gut. Art appreciation — and collection — start with "a feeling in your heart, which will transfer to your brain," he says. "It's a desire to own it and live with it – hopefully."
And if that attachment outstays its welcome, don't be afraid to turn over your collection. Over the years, Belkin has sold art, sometimes even at a loss, to raise cash for a new work he wants to introduce to his household.
Still, there are pieces he would never sell. "It's not my business buying and selling art," says Belkin, noting he developed his artistic tastes on his own, largely by going to art exhibitions and art auctions. His business is sports merchandising and selling tickets to rock shows. Art, for him, is above all a pleasure. js

subset: commoncrawl


text:
- Review
- Open Access
Hypothyroidism and brain developmental players
- R G Ahmed1Email author
© Ahmed; licensee BioMed Central. 2015
- Received: 19 November 2014
- Accepted: 23 January 2015
- Published: 11 February 2015
Most of our knowledge on the mechanisms of thyroid hormone (TH) dependent brain development is based on clinical observations and animal studies of maternal/fetal hypothyroidism. THs play an essential role in brain development and hormone deficiency during critical phases in fetal life may lead to severe and permanent brain damage. Maternal hypothyroidism is considered the most common cause of fetal TH deficiency, but the problem may also arise in the fetus. In the case of congenital hypothyroidism due to defects in fetal thyroid gland development or hormone synthesis, clinical symptoms at birth are often mild as a result of compensatory maternal TH supply. TH transporters (THTs) and deiodinases (Ds) are important regulators of intracellular triiodothyronine (T3) availability and therefore contribute to the control of thyroid receptors (TRs)-dependent CNS development and early embryonic life. Defects in fetal THTs or Ds may have more impact on fetal brain since they can result in intracellular T3 deficiency despite sufficient maternal TH supply. One clear example is the recent discovery of mutations in the TH transporter (monocarboxylate transporter 8; MCT8) that could be linked to a syndrome of severe and non reversible psychomotor retardation. Even mild and transient changes in maternal TH levels can directly affect and alter the gene expression profile, and thus disturb fetal brain development. Animal studies are needed to increase our understanding of the exact role of THTs and Ds in prenatal brain development.
- Hypothyroidism
- Brain development
- Transporters
- Deiodinases
Thyroid hormone (TH) is essential for a number of physiological processes and is particularly critical during nervous system development [1-7]. In developing brain THs stimulate and coordinate processes such as neuronal proliferation, migration, growth of axons and dendrites, synapse formation and myelination [4,7-22]. Disturbance of these processes leads to abnormalities in the neuronal network and may result in mental retardation and other neurological defects, including impaired motor skills and visual processing [23-27]. Hypothyroidism in adults has been associated with mood symptoms and reduced quality of life [16,28,29]. It is estimated that more than 12% of the US population will develop a thyroid condition during their lifetime, and an estimated 20 million Americans have already some form of thyroid disease [30]. Besides, some of the most prominent and common symptoms of thyroid disease are those that result from the effects of TH on the CNS [31].
Types of thyroid hormones transporters and their iodothyronine derivates [16]
Transporter a
Iodothyronine derivates
Specificity b
T3, T4, rT3, T2
T3, T4, rT3, T2, T4S, T3S, rT3S, T2S
T4, T3, rT3
T4, T3, T3S, T4S, rT3S
rT3, T4S, T3S, rT3S
T4, rT3, T3, T4S
T3, T4, rT3
T3, T4, rT3, T2
The importance of THTs for brain development was clearly demonstrated when researchers were able to link mutations in the human SLC16A2 gene coding for MCT8 to a previously described form of X-linked psychomotor retardation, the Allan-Herndon-Dudley syndrome [44,45]. All patients have a severe mental retardation, they cannot speak and most of them are unable to sit upright, crawl, stand or walk. Their thyroid phenotype is quite abnormal with a substantial decrease in plasma T4 and a more than twofold increase in plasma T3 as well as an increase in thyroid-stimulating hormone (TSH). Notably, preterm infants show transient hypothyroxinemia without TSH elevation [46]. In addition, the degree of neurodevelopmental delay in preterm infants becomes severe according to the decreasing gestational age. Epidemiological and animal studies had shown that maternal subclinical hypothyroidism had significant negative impact on neurodevelopment [19,22,47]. To gain further insight in the pathogenic mechanisms underlying these diseases, MCT8 knockout (KO) mice have been generated [42,48]. The serum TH parameters in MCT8 KO mice are affected in the same way as in human patients but surprisingly they seem to develop normally, without overt neurological phenotype. Further analysis showed that the entry of T4 into the brain was not disturbed while uptake of T3 was diminished; suggesting that MCT8 is very important for T3 transport across the BBB and/or BCSFB while the passage of T4 is facilitated by other transporters [49]. The overall T4 and T3 content of cerebrum and cerebellum were decreased by more than 50%, but detailed morphological studies as well as analysis of T3 target genes showed that neuronal uptake of T3 was impaired in an area- or even cell-specific manner. There were signs of a pronounced hypothyroid status in the thyroid-releasing hormone (TRH) producing neurons of the hypothalamic paraventricular nucleus, a mild hypothyroid status in RC3 expressing neurons of the striatum but an apparently normal thyroid status in several cell types in the cerebellum [42]. It was concluded that in mice, more than in humans, other THTs can compensate for the lack of MCT8 in neurons, thereby protecting the brain from severe neurological deficits. The critical restriction to T3 transport in the absence of MCT8 could be located at the BBB rather than the plasma membrane of individual neurons [50]. This agrees with the hypothesis that the high OATP1C1 expression in cerebral microvessels in rodents, as opposed to the situation in humans, contributes to the mild phenotype in MCT8 null mice [51]. Recently also a combined MCT8- and D2-deficient mouse has been described. Analysis of 34 target genes in the cerebral cortex of single and double KO mice demonstrated that the expression of only 3 of them was affected by the elimination of MCT8 alone while this number increased to 24 when both MCT8 and D2 were absent, suggesting that D2 can partly compensate for the decrease in TH uptake in MCT8 deficient mice [52]. While several groups have studied the exact localization of THTs at the level of the BCSFB in the choroid plexus and at the level of the BBB in both macro- and microvessels [51,53], only a few detailed reports are available on their cell-specific distribution in other regions of the brain. In situ hybridization (ISH) for MCT8 in murine brain showed the highest signal in several layers of the cerebral cortex and the hippocampus, in the amygdala, and many basal ganglia. In the cerebellum, expression was predominantly in the Purkinje cell layer. Using specific markers it could be shown that MCT8 is predominantly expressed in neurons, and to some extent in the tanycytes lining the third ventricle [50,54,55]. Analysis of primary murine cell cultures demonstrated high levels of MCT8 protein in neurons and low levels in astrocytes and oligodendrocytes. Importantly, MCT8 deficiency has important metabolic consequences in the brain that could not be correlated with deficiency or excess of TH supply to the brain during adulthood [56]. Also, Müller et al. [57] indicated that MCT10 indeed participates in tissue-specific TH transport and also contributes to the generation of the unusual serum TH profile characteristic for MCT8 deficiency. LAT1 showed the same expression pattern as MCT8 [35]. MCT8 deficiency has important metabolic consequences in the brain that could not be correlated with deficiency or excess of TH supply to the brain during adulthood [56]. In human late fetal brain LAT2 was found only in microglia while in perinatal mice it was also widely expressed in neurons and astrocytes [35,55]. Information on the ontogenetic changes in THT expression in mammalian brain is quite scarce, especially for early developmental stages. In birds, THTs have been studied first in quail in relation to their possible involvement in the regulation of photoperiodicity at the level of the hypothalamus. Four members of the OATP family were found in choroid plexus: OATP1A1, OATP1B1, OATP1C1, and OATP3A2. The ventro-lateral walls of the basal tuberal hypothalamus showed strong expression of OATP1C1 and weak expression of OATP1B1 [58]. Analysis of chicken OATP1C1 substrate specificity in a cell culture system showed that the protein is a highly specific transporter for T4 (Km 6.8 nM) [58]. While MCT8 mRNA levels increased gradually between embryonic day (E) 4 and E10, OATP1C1 expression showed a divergent pattern. The overviews presented here are consistent with the evolving view that the importance of THTs for proper brain development [59].
General characteristics of the iodothyronine deiodinases [16]
Reaction kinetics
Reaction catalyzed (Deiodination)
5 or 5' (ORD+IRD)
Main form
T4-T3, rT3- T2
- T4- rT3, T3- T2
- T4- rT3- T2
Substrate preference
5': rT3, rT3S>T2S>>T4
Sulfation of substrates
Substrate limiting KM
0.5 mM
1–2 nM
5–20 mM
In vitro cofactor limiting KM
1–10 Mm DTT
>10 mM DTT
=70 mM DTT
Molecular mass (kDa)
- Liver, kidney, thyroid and pituitary.
- Pituitary, brain, BAT, thyroida, hearta and skeletal musclea.
- Brain, skin, uterus, placenta, fetus and in other sites of the maternal- fetal interface, such as the umbilical arteries and veins.
Subcellular location
- Liver: endoplasmic reticulum. - kidney: basolateral plasma membrane
- Microsomal membranes
- Microsomal membranes
- Production serum T3 and the clearance of serum rT3.
- Catalyzes the outer ring deiodination of T4 to T3 and is thus important for the local production of T3.
- Catalyzes the inner ring deiodination of T4 to rT3 and of T3 to 3,3'-T2.
Activity in hypothyroidism
- Decrease in liver and kidney.
- Increase in all tissues.
- Decrease in brain.
- Increase in thyroid.
Low-T3 syndrome
- Decrease
- No change
- No change
Active site residues
- Selenocysteine histidine and phenylalanine.
- (Seleno-)cysteine?
- Selenocysteine
Human gene structure and location
- 1p32-p33, 17.5 kb and 4 exons.
- 14q24.3, 2 exons and 7.4-kb intron.
- 14q32
Promoter elements
- TRE, RXR, no CAAT or TATA box.
Propylthiouracil inhibitor
Aurothioglucose inhibitor
Iopanoic acid inhibitor
General summary about the developmental thyroid hormone mechanisms (deiodinases, transporters, sulfotransferases and receptors) in human, rat and chicken [16]
Rodent (rat)
Week post conception
Day post conception
Incubation day
- D3 is detected in uterine wall.
D2 and D3 are observed in uterine wall.
5 h (blastula stage)
- TRα mRNA is noticed and the levels markedly increased during neurulation.
- Thyroid gland begins.
- Time of implantation process.
24 h
- mRNA levels of D1, D2, and D3 are detected in whole embryos.
- Very high D3 activity is detected in decidual tissue.
- TBG is observed in thyroid follicle cells at GD 29.
- Thyroid gland is first visible as an endodermal thickening in the primitive buccal cavity.
48 h
- OATP1C1 expression appears.
- TRH is detected in fetal whole-brain at 4.5 weeks of gestation.
- TH is detected in rat embryotrophoblasts
- T4 is transferred via the placenta and has been found in the gestational fluid sac from 4 to 6 W.
- Maternal-embryo transfer of THs has been detected in embryonic coelomic fluid and amniotic fluid.
- All the mRNAs encoding THTs are expressed in placenta from 6 W and throughout pregnancy.
- T4, T3 and rT3 are detected in coelomic/amniotic fluids.
- T4, T3 and TRβ are detected in embryo/trophoblast unit.
- T3, THTs, Ds and TRs are expressed in whole embryos.
- TRs, D2 and D3 are noticed in fetal brain.
- TSH is first detected in the fetal pituitary.
- OATP1C1 expression is more than 10-fold higher in the telencephalon and diencephalon compared to the mesencephalon and rhombencephalon.
- D2 mRNA levels are highest in the diencephalon.
- The fetus is able to produce THs during this period, but prior to that time, is totally dependent on maternal THs.
- TRα mRNA is widely distributed in fore-, mid- and hind-brain.
- TBG levels are detected in fetal serum and increased through gestation.
- T4 and T3 are detected in embryonic brain.
- TRH is detected in fetal hypothalamus.
- D2 activity is observed in the brain before the onset of thyroid function and increases significantly.
- T4 and T3 are observed in serum and brain.
- Placental circulation established.
- D2 mRNA is noticed in cell clusters throughout the brain, particularly in rhombencephalon.
- Total serum T4 and T3 are low, free T4 is relatively high.
- TRs and TH are observed in fetal brain.
- OATP1C1 levels are declined substantially in all brain regions.
- rT3 is noticed in serum relatively high.
- D3 and D2 are detected in uterus and placenta.
- TH synthesis begins in fetal thyroid.
- Decreased mRNA expression of OATP1A2 but no change for OATP4A1 at 9–12 W compared to term.
- Expressions of mRNAs encoding MCT8, MCT10, OATP1A2 and
- TRH mRNA is detected in neurons of the fetal hypothalamus.
- D3 mRNA levels are markedly different in the telencephalon and diencephalon but remain stable, while the levels in mesencephalon and rhombencephalon show a sharp decrease and increase, respectively, during these days.
LAT1 are significantly lower prior to 14 W compared to term
- Pituitary TSH mRNA expression begins.
- Several elements of the TH action cascade are observed in the brain of embryos long before their own thyroid gland starts hormone secretion.
- TRH mRNA is detected in the developing paraventricular nuclei of the hypothalamus.
- D3 is observed in placenta and fetal epithelial cells.
- TRs are observed in liver, heart and lung.
- The thyroid gland is fully functional.
- D3 and TRs are detected in fetal liver.
- D1 and D2 are noticed in fetal tissues.
- D1 is noticed in heart and lung.
- TRH is produced in low levels in hypothalamus and increases approximately threefold by GDI9.5.
- Significant fetal TH secretion begins.
- Duplication of TBG concentrations.
- TH synthesis begins in fetal thyroid
- Brain D2 is elevated at the peak of neuroblast proliferation.
- TSH protein and Sulfotransferase are observed.
- The total T4 and T3 concentrations in fetuses are increased dramatically because of maturation of hormone synthesis of the fetal thyroid gland.
- The strong increase in intracellular T3 has been observed.
- The coordination between THTs and Ds is regulated both transplacental TH passage from mother to fetus and the development of the placenta itself through the progress of gestation.
- A steady increase in serum TH levels begins and continues to term.
- Significant fetal TH secretion begins.
- Plasma T4 levels start rising markedly around this day.
- Marked rise in serum TH but levels at birth still below those in adult.
- Serum total and free T4 and T3 near and below adult levels, respectively.
- Birth state.
- The decrease in DI activity in gonads is combined with the relatively high D3 activity.
- Thyroid system is less developed.
- The HPT axis begins to mature during the second half of gestation.
- As much as 17.5% of THs found in the newborn are of maternal origin.
- A significant increase in T3 production and in D2-activity and -mRNA expression are combined with a decreased in D3 activity.
- LAT1 and OATP4A1 have been localized only during the third trimester.
- Birth state.
- Brain development equivalent to human birth.
E13/14–E17 (synaptogenesis)
- Brain D2 activity is moderately elevated, whereas D3 activity and mRNA expression are highest between these days, followed by a dramatic decrease thereafter.
- Complete maturation of thyroid system.
- MCT8 has been localized in the placenta in all three trimesters of pregnancy.
- High concentrations of the different iodothyronine sulfates, T4S, T3S, rT3S and T2S, have been documented in human fetal and neonatal plasma as well as in amniotic fluid during the pregnancy.
- Serum TH levels continue to rise and are higher than adult levels between these days.
- D1 and D3 are expressed in the granule cells, whereas D2 is found mostly in the molecular layer and the Purkinje cells at that time.
- The levels of pituitary and serum TSH slowly decrease from PND 14–16 until reaching adult levels at PND 40.
- The increase in brain T3 production correlates with the appearance of TRβ expression in the cerebellum, telencephalon and optic lobes.
- TRH levels increase to adult levels by PNDI7–29, then decrease transiently between PND 31–41; adult levels are once again reached at PND 50.
E20 (at the moment of pipping)
- The brain is quite well developed at the time of hatching.
- Adult TRH mRNA expression patterns are observed at PND 22.
- The gradual increases in plasma T4 and hepatic D1 are detected.
- D3 levels are decreased in spleen and increased in skin and the lungs towards hatching.
- T3 production seems to be elevated markedly in liver.
- The rise of T4 is much more pronounced than in plasma.
- Diminished T4 sulfation is detected.
Complete maturation of thyroid gland.
- The T3 breakdown capacity by D3 is high in liver but low in kidney.
- T4 levels in plasma increase gradually during these days.
- In contrast to TRα expression which increases gradually towards hatching, expression of TRβ shows an abrupt elevation in late development, especially in the cerebellum.
- The majority of tissues express D3 together with either D1 or D2.
- The levels of D3 activity noticed in liver are rapidly drop by more than 90%.
- D1 levels in testis and ovary strongly decrease around hatching.
- Brain D2 activity is moderately decreased, whereas D3 activity is low.
- The low T3/T4 ratio is associated with high T3 breakdown in liver and with high T4 inactivation or T3 secretion in kidney.
- D1 activity gradually increases, reaching a maximum around these period, and decreases slowly to posthatch levels thereafter.
C1 (first day posthatch)
- The expression of D1 is limited to the mature granule cells and that of D3 to the Purkinje cells exclusively, whereas D2 remains clearly noticed in the molecular layer.
- Highest D1-activities and -mRNA expressions are detected in the liver, kidney, and intestine.
- The circulating T3/T4 ratio started to increase gradually during the first week after hatching.
This work was supported by a National Grant from the Research Center, Beni-Suef University, Beni-Suef city, Egypt.
Authors' Affiliations
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This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.


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Kent, Dover, Shakespeare Cliff - image courtesy of Julia Powell
Kent, Dover Castle, QE's Pistol
Kent, Dover Castle
Kent, Dover, Coach Hotel - The Dover Stage Hotel
Photos of Dover in Kent in England, United Kingdom of Great Britain.
Photos of Dover in Kent in England
Kent, Dover, Shakespeare Cliff circa 1890
The above image is kindly shared with us from the personal collection
of Prof. Robert Pearl of Durban, South Africa
Dover is most associated with the sea, and it is the gateway to
Europe for the British peoples. For Brits coming home from abroad,
the first signs of home are the legendary White Cliffs of Dover.
Dover Page 2>>Kent
There is a totally new addition to this website with thousands of contemporary
and old photos of Churches - church photos
England>>>>>> >Ireland> >>>>>>Scotland
Wales>>>>> Isle of Man>>>>>>Channel Islands
>Film and Movie Stars >>>> Home>>>>>> >About
>Privacy Policy>>>>>
Copyright Statement
Kent, Dover, Admiralty Pier in the
Kent, Dover, Gordon Boys Orphanage, Band and
Kent, Dover, Sea Front
Kent, Dover, Shakespeare Cliff
Kent, Dover, White Cliffs
Kent, Dover, Pullman Charabanc - showing Morecroft and Son Shop


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Weapon Ammunition and Common Bullet Sizes
November 13, 2018 Lifestyle Check
Guns can serve military, civilian, or recreational purposes. You can explore the recoil strength and stopping power of the different bullet calibers at Peak Firearms. Components of a Bullet Cartridge A bullet cartridge comprises a bullet, propellant (usually powder), casing, and primer. The bullet itself only refers


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Kilgore and Henderson Matchup Hightlights Football This Weekend
Regular season games for high school football are close to an end, and teams are playing their hardest to get in the playoffs. There are plenty of big games to go around in East Texas. Here's a few big stories to look at from our friends at ETSN.fm:
- Henderson Hopes to Find Cracks in No. 4 Kilgore's Dominant Defense
- Tatum, Jefferson Meet in Matchup of Teams Tangled Atop 9-2A D-I Standings
- Bullard Fights for its Playoff Life at Home Friday Against Gilmer
- Whitehouse Aims for 9-0 When the Wildcats Host Corsicana on Friday
You can also check out the updated list of volleyball playoff match-ups for the week.
For all high school sports updates visit ETSN.fm.


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Planting Information
Growing Calendar - Organic Red Salad Bowl Lettuce
Please enter in your zip code for growing calendar info.
Organic Red Salad Bowl Lettuce is a slow-to-bolt and early maturing variety. Its large, deep lobed, red leaves can be harvested throughout the season and make a delicious addition to a salad.
Out of stock
Available in stores nationwide.
Please enter in your zip code for growing calendar info.
Organic Red Salad Bowl Lettuce is a slow-to-bolt and early maturing variety. Its large, deep lobed, red leaves can be harvested throughout the season and make a delicious addition to a salad.
Sorry, there are no recommended recipes for this item.
Now that your garden is planted and beginning to grow, there are a few key things to know for caring and maintaining your garden. We will look at proper watering, pruning, maintenance, pests, and more.Watch Video
Spring Pea Salad Serves 6-8 People Sweet Green Peas, fresh from the garden or the farmer's market, are so delicious that you don't need to hide their bright color or delicate flavor underneath heavy dressings or a lot of butter. In this recipe, the peas as enhanced by a dressing made with pureed peas, mint,[More…]Read More
Press Release January 2014 Home Farmer, a Home Garden company created in 2012 saw an immense amount of success in their first year of business. From Wal-Mart to Independent Ace retailers across the nation, their seed is gaining popularity and praise from avid gardeners for the top quality product. With feedback from customers, and a[More…]Read More
Proper cleaning and storage is essential to having the tastiest, freshest greens to eat straight from your garden. This works for all garden greens, such as lettuce, kale and spinach. Cleaning is an easy task, but it is very important to do so. Cleaning Pick leaves as you need it so as not to waste[More…]Read More
Organic isn't just a practice, it's a way of life. That being said, a lifestyle change is a big step. Some gardeners who may be interested in adopting some organic practices into their daily lives may not be ready to take the full plunge with their home gardens out of inexperience or fear. For those[More…]Read More
As we get closer and closer to introducing our 2014 Organic Line to the market, we thought it necessary to fully inform you on all the fancy jargon we've been using. It is very important to us that our customers are fully educated on every product we offer and have taken this opportunity to answer[More…]Read More
Parsley Parsley is a common herb, used for its flavor, ability to fight bad breath, as well as a decorative garnish to your dishes. Parsley leaves are also high in nutrients and has been used for a variety of medicinal purposes. This herb can be grown in containers or outdoors directly in your garden. Parsley[More…]Read More
The Dirty 12…. and the top 50 "Dirtiest Produce" from US Department of Agriculture EWG analyzed pesticide residue testing data from the U.S. Department of Agriculture and Food and Drug Administration to come up with ranking for these popular fresh produce items. All 48 Foods are listed below from worst to best. ( Lower numbers[More…]Read More
Herbs can be harvested and used for flavoring a variety of recipes and foods. Often time the plant's leaves are the usable part of the herb plant, and can be used long after the plant dies when temperatures begin to cool. Drying the leaves from your herb garden is a good way to preserve the[More…]Read More
"I wanted some lettuce for my sandwich. Ended up picking about 2 large salad bowlfuls because well we got so freaking much! #gardenproblems" "Attempting nail polish again. We"ll see how long this lasts IBM before it chips. #GardenProblems" "So, uh, slime mold. #gardenproblems" "My back is officially darker than my front #gardenproblems" "Having cut the[More…]Read More
Planning to grow pepper this season? Great! Peppers are chock-full of good flavor and nutrition. Here's a step-by-step guide to help you reap your best pepper crop ever, whether you're starting with your own transplants or planting ones you bought at your local garden center. Check out our article courtesy of Organicgardening.com! 1. Choose and prepare the site.[More…]Read More
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I often receive new age instrumentals in the mail. Everything from Paradiso & Rasamayi to ambient sounds from artists like Aetopus. In August I got a copy of Steven Halpern's Deep Theta 2.0.
Halpern's music style has been called "brainwave entertainment". With his first album released in 1975, Chakra Suite, he set the stage for a new sub-genre in new age instrumental music. Focusing on the brain is something that many musicians have been doing since the 70's. Dr. Michael Brant DeMaria is a prime example of that. But let's focus on Halpern in this review. It is about his newest release, after all.
Deep Theta 2.0: Brainwave Entertainment Music for Meditation and Healing: With bamboo flutes and keyboards, Halpern takes you into a unique brainwave state on the Theta level. 2.0 is a companion to his earlier release of Deep Alpha. Both put the listener into the proper state for deep relaxation and better mental health.
Each track is titled Deep Theta 2.0. In 13 parts you have the opportunity relax, mediate, or go into a deep sleep. Thought the track titles might not be very creative, the music is. The bamboo flutes trigger a mental response that is only found through that instrument. A silver flute, a wood flute, just about any other flute has a different mental response. Where the bamboo flute takes a person is so much different from other types that it cannot be explained in words.
The keyboards are a simple, yet evocative, addition to the musical theme. They take one step deeper into your relaxation.
I've personally found this CD, and others by Halpern, to be a good way to calm the nerves and relax the body. His music has aided me in avoiding the need for medication for my blood pressure. Though I would caution any blood pressure patient to seek medical advice and not use music as the sole means of controlling the issue. I've also found that the music inspires me to write and to take a a moment or several to enjoy what is going on around me.
Like most other new age instrumental music, I would suggest that you not listen to Steven Halpern's CDs while driving. The mental state the music puts you into is deeply relaxing and can distract from driving and other attention intensive activities. But if you are wanting to relax, meditate or have a good night's sleep – even a short nap, this kind of music is perfect for that.
As a radio host, I do find it a challenge to find instrumental music of this kind that works on the radio. Not only because many of my listeners may be on the road and I do not want to distract them from driving, but because many new age instrumentalists have low notes, slow notes, or even silent notes (pauses) in their compositions. That doesn't work with radio very well. However, for internet broadcasting it is nearly ideal.
Take a listen to the first track from Steven Halpern's Deep Theta 2.0 in this YouTube video:


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Juki DU-1181N
1-needle, Top and Bottom-feed, Lockstitch Machine with Double-capacity Hook
With its strong top and bottom feed mechanism, the Juki DU-1181N machine insures the smooth feeding of hard-to-feed materials or multilayered sections of materials to achieve consistent seam quality that is free from irregular stitch pitches. The automatic lubricating mechanism dramatically improves maintainability of the machine.
Higher lift of the presser foot
The lift of the presser foot, by the knee lifter, is as high as 15 mm so as to support processes which require a higher lift of the presser foot, such as piping and tape-attaching
The maximum stitch length is 9mm
With its stitch length being as large as 9 mm, the machine is applicable to a broader range of sewing processes.
The double-capacity hook is provided as standard
The Juki DU-1181N machine comes with a horizontal-axis double-capacity hook, not only to decrease the frequency of bobbin thread changing, but also to enable sewing work with increased efficiency.
Automatic lubricating mechanism
A pump-unit type automatic lubricating mechanism dramatically improves maintainability. The oil amount in the face plate and hook is adjustable.
The top feed mechanism employs a grease tank and oil wick lubrication mechanism.
The Juki DU-1181N machine achieves low-vibration and low-noise
The Juki DU-1181N machine head is designed to achieve optimum balance, thereby reducing vibration and noise. The machine affords the operator a comfortable working environment.
Excellent operability
The stitch pitch can be adjusted in both the normal and reverse directions.
The height and inclination of the feed dog can be adjusted.
The amount of the alternating vertical movement of the walking foot and presser foot is adjustable in a range from 2 to 5mm according to the height of a multi-layered section of material.
The horizontal feed cam, top and bottom feed cam and top feed cam can be adjusted after openning the rubber caps ( three caps ) on top of the machine head.
|Model Number
|Juki DU-1181N
|Max. sewing speed
|Max. stitch length
|9mm (forward/backward)
|Needle bar stroke
|Lift of the presser foot
|By hand: 5.5mm, By knee: 15mm
|Thread take-up
|Link type
|Alternating vertical movement
|Horizontal-axis full-rotary double-capacity hook
|Needle (at the time of delivery)
|DP×17 (#21) #14~#23 *The DB×1 needle can also be used
|Pitch changing method
|By dial
|Knee-lifter mechanism
|Built on the machine head
|Lubricating oil
|JUKI MACHINE OIL No.7 (equivalent to ISO VG7)
|Distance from needle to machine arm
|Bed size
|Weight of the machine head
For all Industrial Sewing Machine Spare Parts, Needles & Accessories, click the link below to our Parent company, College Sewing Machine Parts Ltd, the UK's largest Industrial Sewing Machine Spare Parts Stockist. Juki Industrial Parts Agents, sewing machine parts for the Juki DU-1181N
Just fill out the form below with details of the machine on offer and we will see if we can beat or match the price.


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Tender Arrangements for the issue of Commonwealth Government Securities
13 July 2005
Op Notice No. 09/2005
The Australian Office of Financial Management (AOFM) has reviewed arrangements for the conduct of tenders for the issue of Commonwealth Government Securities (CGS). The review included consultation with firms that are regular participants in CGS tenders.
Following the review and after consultation with the Reserve Bank of Australia (RBA) it has been decided to shorten the period between the closing time for submitting tender bids and announcement of tender results. It has also been decided to conduct a tender for a new electronic system for the collection and processing of CGS tender bids. The changes are aimed at further enhancing arrangements for the issue of CGS and ensuring the Australian Government continues to issue CGS on the best possible terms. Further details are provided below.
Speed of tender result announcements
Currently the closing time for bids in CGS tenders is 12:15 pm on the day of a tender, with results announced thirty minutes later i.e. 12:45 pm. In future results for CGS tenders will be announced as soon as practicable after the close of bidding.
- It is expected that tender results will normally be announced within fifteen minutes of the close of bidding.
- There will be no change to the closing time for bids.
- This arrangement is expected to be implemented for the first time with the Treasury bond tender currently scheduled for 26 July 2005.
Acquisition of new electronic tender system
CGS tenders are currently conducted by the RBA on behalf of the AOFM. Bids are submitted via the Reserve Bank Information and Transfer System (RITS). Only institutions that are members of RITS may lodge bids.
The AOFM is planning to conduct an open tender for procurement of a new electronic system for the collection and processing of CGS tender bids. A new system is expected to provide scope to further improve CGS tender arrangements, including a further reduction in the period between the closing time for tender bids and announcement of the results.
- It is expected that a request for tender for this procurement will be issued towards the end of 2005.
Subject to being able to acquire a system which satisfactorily meets the AOFM's requirements, the new system is expected to become operational in the 2006-07 financial year.
Last updated: 21 March 2014


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Welcome to ETC Educational Technology Connection (HK) Ltd!
CD-Rom with Booklet
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Ten-minute literacy starter activities for whole-class or group teaching, specifically designed to be used on an interactive whiteboard.
High-quality animation, music and sound effects are designed to grab children's attention and get them switched on. Also Included Photocopiable activity sheets in PDF. 8 Word Level Activities:build on early phonics work, looking at consonant clusters digraphs and rhymes and investigating different ways of pronouncing graphemes. There is also a focus on spelling, including the introduction of plurals 8 Sentence Level Activities:focus on the correct use of punctuation, including capital letters, full stops and question marks. Other activities explore the role of word order in conveying meaning and emphasise the importance of checking writing for sense. 8 Text level Activities: encourage children to give personal responses to characters, themes and settings in stories and animations. The activities also lead into a variety of speaking,listening and drama activities such as retelling stories, reading aloud with expression, role play and improvisation and group discussion


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