text:
The recent election of Republican Dean Tran of Fitchburg to the Massachusetts state Senate was an embarrassing rebuke to the state's top Democrats, including U.S. Sen. Elizabeth Warren.
Despite their opposition, Tran defeated Democrat Susan Chalifoux Zephir, a Leominster city councilor who had the support of the state's Democrat Party hierarchy, as well as Charlene DiCalogero of Berlin an unenrolled candidate Claire Freda.
Tran, 42, was sworn into office Wednesday by Gov. Charlie Baker, thereby becoming the first Vietnamese-American to be elected to the Massachusetts Legislature.
The special election was to fill the vacated seat of former Sen. Jennifer Flanagan, a Democrat from Leominster, who was appointed to the Cannabis Control Commission.
The heavily Democrat district is made up of Fitchburg, Gardner, Leominster, Berlin, Bolton, Lancaster, Lunenburg, Sterling, Townsend, Westminster and two precincts in Clinton.
What the election showed was that a Republican -- the right Republican with the right message -- can get elected in Massachusetts, despite the odds.
And Tran faced serious odds. While Gov. Baker and Lt. Gov. Karyn Polito campaigned for him, Democrats Warren, U.S. Sen. Eddie Markey, U.S. Rep. Niki Tsongas, state Treasurer Deb. Goldberg and Attorney General Maura Healey all campaigned against him and for Chalifoux Zephir.
Talk about the majority beating up on a minority.
What stood out in the campaign was the effort of the leading Democrats in Massachusetts, who believe in diversity, inclusion and identity politics, to campaign against a qualified American of Vietnamese descent who was brought to the U.S. by his refugee parents when he was a toddler.
Dean was born in Saigon. His family fled the country upon the fall of Saigon and the Communist takeover. He lived in a refugee camp in Thailand for two years until his family was sponsored by a Roman Catholic priest in Clinton.
He family relocated to Fitchburg where Tran graduated from Fitchburg High School. He then earned a bachelor's degree from Brandeis University. He has worked in the private sector for 23 years.
With his background -- born in poverty and working his way up to the middle class -- the Democrats should have embraced Tran as one of their own.
Instead they embarrassed themselves by campaigning against him. Yet Tran won the election by 7,289 votes to 6,614 votes for Chalifoux Zephir.
This means that, despite all their campaigning, and all their political firepower, Warren, Markey, Tsongas, Goldberg and Healey combined could only turn out 6,614 votes for their candidate in the heated political contest.
It was obvious that Tran struck a chord with the voters, a chord that entirely escaped the Democrat hierarchy. As professional politicians they should be ashamed of themselves.
"You can't believe how many voters are frustrated with the politicians in Massachusetts, in the Commonwealth," Tran said following his victory in an interview with the Boston Herald.
"First, they don't listen to them, and second, they go to Beacon Hill and do whatever they want to do, and they (the voters) are tired of that. And they really appreciated that I was at their doorsteps and just listening to them," he said.
"It resonated with them, and they showed it at the polls," Tran said.
Send comments to: firstname.lastname@example.com


text:
I might not be too big a fan of vanilla slices, but having heard all the raves about THIS vanilla slice, I couldn't possibly say no to a visit to French Lettuce.
Sandwiched between two crumbly crust pastry, was this heavenly soft vanilla custard which thankfully, wasn't too overwhelmingly sweet. It is nice eaten on its own, but also goes just as well with a drizzle of strawberry jam.
Not sure if this is the best I've had, but it sure was good! ;)
Would I return? For sure. But maybe not for the vanilla slice.
They have so many other things behind the glass counter that I'd love to try, someday.

subset: commoncrawl


text:
Now at select Sun Spa Shops. Lose 2 dress sizes in 30 days with Slim Sculpt.LEARN MORE
Want to see the biggest event in country music? Sundays is giving you the chance to win a trip for two to Nashville: airfare, tickets, and the VIP experience!LEARN MORE
Now available at all Sundays locations, M Stiks offer you functional hydration to help you take on the day. Just add one M Stik to 16 ounces of water after a session in one of our tanning beds or spa equipment for a refreshing burst of energy and goodness.LEARN MORE
The Sundays Buddy Pass lets you bring a friend along to tan for free! Get the details here.SHARE THE LOVE
The Cocoon Detox Spa works by heating your body with infrared light rays, which burns calories, releases toxins and gives your skin an all-over glow. Emerge fresh and beautiful as a butterfly!LEARN MORE
With Automatic Airbrushing, your tan is just a short spritz away. Choose from a variety of sun-kissed shades, step into our luxury spray tan booth, and step out looking glamorous.LEARN MORE
The Sundays Buddy Pass lets you bring a friend along to for free! Get the details here.SHARE THE LOVE
Our members have consistently voted us the Best in Hampton Roads for luxury UV tanning and spa services. Experience the Sundays Life at any of our 21 locations.
Sundays offers massage therapy, the Cocoon Slimpod, automated spray tanning and innovative red light skin therapy. Look and feel amazing!
Sign up to receive alerts on Spa Shop specials, including discounts on tanning lotions and skin care, and information on Blue Bucks and Spa Bucks.
Membership plans start at only $18.88 a month – Still the best deal in Hampton Roads. Members can also use the Buddy Pass and let a friend tan free!
VersaSpa at Sundays Sun Spa Shop is engineered to deliver low pressure, high volume automated airbrushing. Step inside this booth and you will be amazed with how quickly and evenly the spray is distributed over your body – with no lingering mist!
The Physedge Fit Infrared System can help you lose weight and inches, break down fat, reduce cellulite, and make your skin appear younger all while you read a book, watch a movie, or relax!
Fit Body Wrap System
Sundays is growing! We're looking for energetic, friendly people to join our team and have fun while helping our members look and feel great.
All of us at Sundays Sun Spa Shop believe our members deserve the best - whether it's luxury tanning, premium lotions, or relaxing spa amenities. With 21 locations in Hampton Roads, it's never been so convenient to unwind after a long day of work or to get ready for the…READ MORE
Sundays Sun Spa Shop offers twenty-one resorts in the Hampton Roads area for your convenience. All salons are open Monday – Friday from 7am – 10pm and Saturday – Sunday from 8am – 7pm, unless otherwise noted on specific holidays. Check our Facebook page for special hours during holidays.


text:
Our philosophy is that all students can achieve; therefore, we are committed to identifying and meeting the diverse needs of each student through individualized educational programming. It is our mission to work cooperatively with families, students, community, colleagues, and other professionals in order to promote each student's success and well-being as he/she prepares for future endeavors
"Education is all a matter of building bridges."
-Ralph Ellison


text:
Canon PIXMA MG5760 Driver Download and Install for Windows, Mac OS, and Linux - The Canon PIXMA MG5760 All-in-One printer. Flaunting functions like Mobile/Tablet printing, scanning, Cloud Web link and other Cloud Print Applications. With a useful 2.5" LCD Screen and a variety of innovative printing software, it's perfect for every one of your personal, work and also household printing demands.
It's an A4 inkjet printer with a level account and also a footprint that takes up regarding 43x38cm on a work desk, and there is an A4 flatbed at the top for scanning and also Canon MG5760 copying files. The main paper tray sits at the base of the printer and can be loaded from the front, with prints showing up at the overlook the resulting plate simply above it. This suggests that the paper course is rounded, yet you would barely know that from the straight, unbent outcome that is received.
The printer MG5760 excelled as well as used for air printing. Lately, the printer threw up a message re-enrollment with Canon. Currently, AirPrint in any way from the cloud though it still duplicates as well as scans. I am unable to register the printer as I do not want my private papers being with Canon neither Google etc. As I can not deal with the printer, so a pricey trip to a techie is now essential as well as possibly ago back to connecting the printer to the computer system with a cable.
The PIXMA MG5760 Ink, Six ink cartridges need to be installed before you could start using the printer, as well as these sit in the print head that travels entrusted to a right as the paper rollers feed the sheet listed below. You won't find capillary tube technology on this model. To mount the cartridges, which include two black containers, gray, cyan, magenta, and yellow, you have to raise the top panel where the LCD screen resides. It's easy to do, as the auto mechanics of it are smooth and also well created.
Also, recommend: Canon PIXMA MG5721 Driver Download
Canon PIXMA MG5760 Specification:
- Ink Droplet Size: 2pl/5pl (C/M), 5pl (BK/Y), 13pl (PGBK).
- Printing Resolution: 4800 (horizontal) 1 x 1200 (vertical) dpi.
- Print Speed: B&W: 12.6 ipm, Colour: 9.0ipm, 4"x6" photo paper: Approx. 41sec.
- Paper Capacity: Plain paper: A4, A5, B5, LTR=100 Sheets / LGL=10 Sheets, 4"x6" photo paper = 20 Sheets, 5"x7"/8"x10" photo paper = 10 Sheets.
- Supported Paper Sizes: A4, Letter. Legal, A5, B5, Envelopes (DL, COM10), 4"x6", 5"x7", 8"x10".
- Supported Paper Weights: Plain Paper: 64-105 g/m2, Canon specialty paper: max paper weight: approx. 300 g/m2 (Photo Paper Pro Platinum PT-101).
- Wireless LAN Range: indoor 50m (depends on the transmission speed and conditions).
- Wireless LAN Security: WEP64/128bit, WPA-PSK(TKIP/AES), WPA2-PSK(TKIP/AES).
- Wireless LAN Network Type: IEEE802.11n/IEEE802.11g/IEEE802.11b.
- Mobile Phone/Tablet Printing: Print/Scan with any Apple or Android devised through the PIXMA Printing Solutions App. Access Point Mode enables printing directly without a router. Cloud integration with Cloud Print Apps. Apple AirPrint supported.
- Interface: Hi-Speed USB (USB Port B) / Card slots available.
- Speed: Colour document: Approx. 20sec / 7.2ipm.
- Multiple Copy: Max. 99 pages.
- Reduction/enlargement: 25% to >400%.
- Special Copy Functions: Two-sided, borderless, 2 on 1,4 on 1, fit-to-page.
- Scanner Type: Flatbed CIS.
- Scanning resolution: 1200 x 2400 optical dpi.
- Scanning Speed (Reflective): Approx. 19sec.
- Smart Device Print Plug-In: Available (for Android / Amazon device).
- Colour LCD Screen: LCD (2.5 inch / 6.2 cm TFT colour/Touch).
- Included as Standard: PIXMA MG5760 Printer, Setup CD-ROM and operational guide, 5 individual ink tanks, sample photo paper, power cord and Canon warranty card. A-BUSB cable to connect to a computer not included.
- Environment: Eco-Label: Energy Star.
- Power Source: AC100 - 240V, 50/60Hz.
- Power Consumption: Off Approx. 0.2W, Standby (scanning lamp is off) connection to PC: approx. 0.7W, Copying (USB connection to PC) approx. 12W7.
- Dimensions (W x D x H): Approx. 455 x 369 x 148 mm.
- Weight: Approx. 6.3kg.
Canon PIXMA MG5760 Operating System Compatibility:
- Windows 10
- Windows 8
- Windows RT
- Windows 7, Windows 7 SP1
- Windows Vista SP1, Vista SP2
- Windows XP SP3 32-bit
- Mac OS X v10.3.9 to 10.5, Mac OS 10.7(Sierra) or later
- Linux
Canon PIXMA MG5760 Wireless Setup:
- Turn on wireless communication in your Canon PIXMA MG5760 printer.
- Enable "Wi-Fi" on your device's "Setting" menu.
- For more on turning on wireless communication, see your device's instruction manual.
- Select "DIRECT-XXXX-MG5760 series" ("X" represents alphanumeric characters.) from a list displayed on the device.
- Enter a password to connect your device.
- Your device is connected, and ready to print with wireless on your Canon MG5760.
Instructions to Setup or Install Canon PIXMA MG5760 Driver:
- When the download has completed, open the file where the file was downloaded. Then click on file.
- You can accept the default area for storing data. Click Next, and then wait while the installer pulls out the data to get ready for installment on your computer.
- When the installation process is complete, the computer restarts your computer system.
- Then test to examinations as well as print check review.
Instructions to Uninstall Canon PIXMA MG5760 Driver:
- In the start Menu on your computer opens control panel.
- In Control Panel menu chooses to Uninstall a Program.
- When Uninstall a Program has opened, you can select the driver that you want to uninstall.
- After a uninstalling process is complete, restart your computer to make computer working normally again.
Canon PIXMA MG5760 Driver Download
Operating System
|MG5760 series Full Driver & Software Package (Mac)
|MG5760 series Full Driver & Software Package (Windows 10/10 x64/8.1/8.1 x64/8/8 x64/7/7 x64/Vista/Vista64/XP)
|MG5760 series CUPS Printer Driver Ver. 22.214.171.124 (Mac)
|ICA Driver Ver.4.1.3 (Mac)
|XPS Printer Driver Ver. 5.90 (Windows)
|ScanGear MP Ver. 3.20 for Linux (Debian Packagearchive)
|ScanGear MP Ver. 3.20 for Linux (rpm Packagearchive)
|ScanGear MP Ver. 3.20 for Linux (Source file)
|IJ Printer Driver Ver. 5.20 for Linux (Debian Packagearchive)
|IJ Printer Driver Ver. 5.20 for Linux (rpm Packagearchive)
|IJ Printer Driver Ver. 5.20 for Linux (Source file)
|MG5760 series MP Drivers Ver. 1.00 (Windows 10/10 x64/8.1/8.1 x64/8/8 x64/7/7 x64/Vista/Vista64/XP)


text:
Home > Children At Risk > JFS > Vol. 1 (1995) > Iss. 2
Article Title
Improving Family Functioning Through Family Preservation Services: Results of the Los Angeles Experiment
This article describes a study of the outcomes of home-based family preservation services for abusive and neglectful families in Los Angeles County. It focuses on changes in family functioning during the 3 month service period and one year after case closing. Families known to the public child welfare agency were referred to the project based on caseworker judgement of the need for services rather than on the criteria of imminent risk of placement. Two hundred forty families were randomly assigned to either the service group receiving family preservation services from two non-profit agencies or to the comparison group receiving regular public agency services. Both caseworkers and families reported small but significant improvements in family functioning for the service group families, but not for the comparison group families. Study findings also suggest the aspects of family functioning most changed by services, the characteristics of families most affected by services, and variables which predicted service success.
Recommended Citation
Meezan, William and McCroskey, Jacquelyn
"Improving Family Functioning Through Family Preservation Services: Results of the Los Angeles Experiment,"
Journal of Family Strengths: Vol. 1
, Article 5.
Available at: https://digitalcommons.library.tmc.edu/jfs/vol1/iss2/5


text:
There has been a lot of issues in the past few years about the continual and gradual worsening of the quality of tap water all over the world. The decrease in fresh water supply has worsened the quality of tap water even to the point of people questioning its safety as a drinking-class water. This problem has led several manufacturers to produce water filter systems that aim to reduce the particulate matter and impurities in our water system. But considering the wide variety of water filters available, how should you choose the best filter system for your home?
In what way will you use the water that you are filtering? Are you using it for drinking or for simply softening your shower water? In any ways, always note that there isn't a one-type-fits-all filtering system. Different needs call for different numbers and kinds of filters so you should list out first where you would be using the water by which you would want to filter.
If you are using the water for laundry or for shower, you would need a pre-filter that will filter the particulate matter and other impurities that are below 15 microns. Also, you would need this to remove the chlorine traces in your water. You would also need to add a water softener in order get rid of minerals.
If you are using the water for drinking, then in addition to the pre-filter, you would need another stage of filter system that is made of carbon filter which will necessary narrow down the particulate matter to 0.5 microns. After that you would need another normal water filter that can be bought in markets. You might want to invest in an ozone technology filter which will not only filter the particulate matter but also disintegrate the DNA of any bacteria or virus, hence making your water completely safe.
Research where your government derives its water; may it be from a reservoir, a river or any other stream. Once you know, research what class of river that is and further research the kind of contaminants that river has. After you know the contaminants, list it and the water filtering company should be able to give you the type of treatment machine you would have to purchase in order to purify your water.
Try to canvass first the types of filters that suits your needs. After that, look for several reviews and opinions from real people who purchased the same filter. From then on you can know whether that filter is worth your investment or will it just cost you several disappointments.
Research on the types of tests that were conducted by that company and see whether your government has really approved of that device. Research whether the company is still starting out or has it produced lots of products before. You would want to trust a company that has been in that trade for a long time compared to a company who is still starting out.
Also, remember that your family's safety is always at stake with this decision so invest wisely. It does not mean that just because it is cheap, then it is already a good buy. After all, if your family would only get sick afterwards, then it would cost you even more. It also does not mean that just because it is expensive, then it is effective. Weigh down its features and uses and also take into consideration the authenticity and the name of the company. Settle for a system that has a warranty system since this is a good sign that the company is confident enough with their product.


text:
MAPFRE Insular, a non-life insurance company, introduces the new VIP Fast Track program. The VIP Fast Track is another trailblazing innovation in the claiming process for MAPFRE Insular Comprehensive Car Insurance policyholders.
Wednesday, August 26, 2015
Thursday, August 20, 2015
Smart Enterprise and PLDT SME Nation unveil first ever Bozz Awards
Smart Enterprise, under PLDT SME Nation, has unveiled its latest initiative to empower the new breed of Filipino entrepreneurs with the BOZZ AWARDS. It is a social media crowdsourcing search for the new generation of entrepreneurs who are harnessing digital tools to grow their businesses. These entrepreneurs are known for spearheading a revolutionary change in business platforms through their use of technology.
LOVED by Sugarsmile at 2:54 AM 0 comments Links to this post
Labels: Bozz Awards, contest, entrepreneurs, PLDT, PLDT SME Nation, Rappler, Smart Enterprise
Tuesday, August 18, 2015
Seven Corners Presents Chef Bruce Lim's Dishes
Seven Corners, the premier buffet destination in Ortigas District, partners with one of the country's renowned culinary master, Chef Bruce Lim. This August 16 to 31, the celebrity chef will prepare his masterpieces at the buffet spread of the restaurant.
LOVED by Sugarsmile at 3:27 AM 0 comments Links to this post
Labels: buffet, Chef Bruce Lim, Crowne Plaza, Crowne Plaza Manila, Filipino Cuisine, Filipino Food, Food, foodie, Seven Corners, yummy
McDonald's Shake Shake Fries is Shaking Back!
Shake, shake, shake! With McDonald's, you can expect another exciting snacking experience with the return of the Shake Shake Fries.
LOVED by Sugarsmile at 12:33 AM 0 comments Links to this post
Labels: Food, French Fries, McDonalds, Shake shake Fries, yummy
Monday, August 17, 2015
Samsung Launches the Galaxy Note 5 and S6 Edge+
New phones, new innovation. Samsung truly lives up to its name in creating smartphones that are not just large, but also large in features. And last Friday, August 14, Samsung Electronics Co., Ltd. announced in New York City, USA the global launch of the Galaxy Note5 & the Galaxy S6 edge+.
Bigger, better and more powerful - that is Samsung's promise to its consumers with its two new incredible devices for people who is never afraid to live big and pursue their passion in the most efficient and productive way. I, for one, is a believer of multitasking, and Samsung can help us in that aspect.
LOVED by Sugarsmile at 3:00 AM 0 comments Links to this post
Labels: big screens, Enhancements, phablet, S Pen, Samsung, Samsung Galaxy Note 5, Samsung Galaxy S6 Edge+, Samsung Smartphones, Technology
Thursday, August 13, 2015
Repertory Philippines Presents Snow White and The Seven Dwarfs
Mirror, Mirror on the wall, who is the fairest of them all? Snow White's tale is one of the classics we all know and love. And this August 15, Repertory Philippines returns onstage with its own staging of Michael Valenti and Elsa Rael's adaptation of the classic fairy tale --- Snow White and the Seven Dwarfs. But, Rep's version is more than just a simple retelling of Snow White. It features an enthralling fusion of live music with mesmerizing choreography and classical ballet unfolding right before your very eyes.
LOVED by Sugarsmile at 11:49 PM 0 comments Links to this post
Labels: classical ballet, fairy tale, Greenbelt, Play, Repertory Philippines, Show, Snow White
Wednesday, August 12, 2015
Update your Starmobile Engage 10 Pro to Windows 10 Today!
Starmobile ENGAGE 10 Pro users can now update their devices for free as Microsoft Windows 10 is now available for download!
LOVED by Sugarsmile at 1:18 PM 0 comments Links to this post
Labels: Starmobile, Starmobile Engage 10, Technology, Windows 10
Friday, August 07, 2015
Imagine Dragons to Perform Live in Manila!
Grammy-Winning Alternative Rock Band Imagine Dragons performs live in Manila thos August 15 at the Mall of Asia Arena. The SMOKE + MIRRORS Tour is a celebration to their massively successful debut in 2012.
LOVED by Sugarsmile at 12:30 AM 0 comments Links to this post
Labels: Imagine Dragons, MMI Live, MOA Arena, SM Tickets, Smoke + Mirrors Tour
Thursday, August 06, 2015
Oishi Snacktacular is Back!
LOVED by Sugarsmile at 4:21 PM 0 comments Links to this post
Labels: 2015, Alex Gonzaga, August, Daniel Padilla, Elmo Magalona, foodie, Kathryn Bernardo, Oishi, Oishi Snacktacular, Ramon Bautista, Slater Young, snacks, Trinoma Activity Center
7-Eleven Takes Filipino Dishes to the Next Level
Home-cooked Filipino meals are the best. Don't you just agree? And now, the world's leading convenience store —7-Eleven, is not just your one-stop shop but also as a diner that offers quality home-cooked style meals at a very affordable price. And more good news is that it is available now.
LOVED by Sugarsmile at 2:22 AM 0 comments Links to this post
Labels: 7-Eleven, affordable, Bistek Tagalog, Chef Claude Tayag, Chef Creations, convenience, Food, foodie, Pork Binagoongan
Tuesday, August 04, 2015
Fly to Bangkok, Singapore or Hongkong for free as new Citigold client
Experience world-class wealth management services with Citigold, Asia's leading wealth management partner, and enjoy exclusive welcome gifts in travel, accommodation and dining.
Simply visit a Citibank branch and open a new Citigold account with a starting balance of Php4 million. The higher your opening balance, the better the rewards. With at least Php10 million to as much as Php 25 million, you can get a free roundtrip voucher to anyone of these exciting Asian destinations: Bangkok, Singapore or Hong Kong.
You can also opt for a luxurious overnight stay for two in Edsa Shangri-la with buffet breakfast at HEAT or at Marco Polo Cebu with buffet breakfast in Café Marco and set dinner at El Viento, or choose to own a high-end travel essential like a 66 cm Samsonite Sigma Hard Case luggage. Reach your financial goals and get these exclusive rewards from Citigold.
Promotion runs until August 19, 2015. For more details and to see the complete list of welcome gifts, call the 24-hour Citigold Hotline at 995 9888.
Source: CitiGold Press Release
LOVED by Sugarsmile at 12:35 AM 0 comments Links to this post
Labels: Asian Trip, Citigold, promo, Reward, rewards
Throttle Philippines, First App-based Interactive Motoring Magazine in the Philippines Kicks Off
Last July 25, Throttle Philippines, the first App-based interactive motoring magazine in the Philippines, kicked off in a testosterone packed party that saw the gathering of elite hardcore motorcycling clubs and muscle motorcycle displays. Proudly developed by an all-Filipino team, Throttle Philippines was built to give Filipinos everywhere a fast and easy access to the latest news and updates in the motoring industry.
LOVED by Sugarsmile at 12:22 AM 0 comments Links to this post
Labels: digital magazine, Magazine, Mobile App, motorcycle, reading, Tablet, Throttle, Throttle Philippines
Saturday, August 01, 2015
Experience the Great Taste of Winning with Great Taste White
Choose Great, Win Great with Great Taste White by giving away Php27M worth of prizes at stake. The promo will have four regional draws in five areas: Greater Manila Area, North Luzon, South Luzon, Visayas and Mindanao. For every regional draw, there will be one winner of P200,000 and one winner of P100,000 in each area. Two winners will also get their very own white MacBook Air, four winners will take home a white iPhone 6, and six winners will receive a white iPad Mini.
LOVED by Sugarsmile at 1:29 AM 0 comments Links to this post
Labels: coffee, Daniel Matsunaga, Great Taste White, PBB, prizes, promo
Subscribe to: Posts (Atom)


text:
I have long been turned on to the magic that is goat's milk cheese. Whether its fresh chevre in a salad or the tangy hint of goat cheese in a luscious berry topped cheesecake, call me a fan. But though I frequently peruse the myriad cheese plates gracing our local restaurants' menus, I didn't fully appreciate just how darn good sheep's milk cheese can be until this weekend.
While wandering around the Dupont Farmers Market - my favorite Sunday morning pastime - I saw a stall I hadn't really noticed before, Everona Dairy, where they were handing out delicious samples of their farmstead sheep's milk varieties left and right. Not only did I walk away with a hefty hunk of nutty Piedmont, their signature cheese, but I also got a tub of their Rapidan spread, a tapenade-style dipping 'sauce' that's got the Piedmont cheese mixed right in. Dolloped into a pot of hot orzo with some fresh basil and chopped heirloom tomatoes thrown in for good measure, we had one of my favorite meals of the summer. Yay sheep.
Monday, August 3, 2009
Hail to the Sheep
Labels: cheese, farmers' market, pasta, summer dishes
3 comments:
- prepaid game card said...
I know I'm lactose intolerant but of all the eatable stuff here on earth my favorite is cheese and milk. YUM YUM!
- November 20, 2009 at 6:06 AM
- receptionist jobs said...
Oh! I love this wrote it very deliciously and it looks very delicious and healthy. It made me really hungry.
- November 20, 2009 at 6:08 AM
- furniture restoration toronto said...
ohh,i love this..what's the recipe to this dish? i love cheese..
- October 30, 2012 at 10:45 PM
Subscribe to: Post Comments (Atom)


text:
"This was the most hassle-free move I have ever experienced. Moving Company Elmont coordinated every aspect of my family's move. Everything arrived right on time and finished earlier than planned. They handled all of our household items with care and could not have been friendlier. No matter where I move next, Moving Company Elmont will take me there."- M. Westrick
Moving Company Elmont is a full service moving company serving Elmont and the surrounding areas. Our local movers have been performing professional moves for both residential and commercial properties for several years. The licensed movers also provide full packing services that include pod, rental trucks and container loading and unloading assistance. Contact us today to plan your upcoming move. Our local movers as well as long distance movers will be more than happy to assist you with any type of move you may have. Moving Company Elmont knows that moving can be one of the most stressful times in your life, that is why our licensed movers are fully trained with all the essential skills needed to execute the move in a flawless and efficient way.
Whether you're moving your family or your company, whether you're moving near or far, whether you've been planning your move for months or it's an emergency move, Moving Company Elmont is standing by with a free instant estimate and a certified moving consultant to help you create the most efficient plan possible. We are your best choice for residential and commercial moving in Elmont. We're a full service moving company providing packing and crating with warehouse storage.
If you require moving material such as packing boxes, packing foam or quilted padding, we will provide that to you at very reasonable prices. Our moving trucks are fully equipped with all the needed equipment to fully execute your move from start to finish. The trucks are fully padded so you can be sure that your belongings will be out of harm's way and transported safely to your new location. Our long distance movers are trained to take care of your out of state moves that require more thought and consideration when moving your belongings. Let Moving Company Elmont be your moving company. We will provide you with exceptional service from start to finish. So, don't delay and call today!


text:
I scribbled these in my mind as I went to work, then as I did some of my routine duties. I thought some of them were rather witty:
Kissed by sheets of ice
Groaning with much obstinance
My car moves at last.
Scrubs are a thin veil
The winter's rage pours through me
Sweatpants underneath.
Scorn fills the elevator
Tacobell's malice.
Why must you smile so?
We are five thousand employed
We shan't meet again.
Icy paws of doom
Descend to ruin your slumber
Diagnostic wrath.


text:
In October 1999, Monica Pasinato-Forchielli and her brother John-Paul Pasinato opened their first Massage Therapy Clinic on Mohawk Road East at Upper Gage. Six months later, Monica, along with her sister-in-law, Lorna Pasinato, opened their second location on Concession Street at Upper Wentworth. This location is now the home of North America's first ONE Concept Clinic, Spa and Shop. Through continued research and education, Family Massage Therapy continues to provide the newest and most innovative products and services to the health professional industry and to their clients. Family Massage Therapy is dedicated to providing education, environmentally friendly products and healthy practices in order to preserve and restore our ONE planet.
A feeling of serenity, healing and happiness engulfs you as soon as you enter the building. Healing energy will find you through our many diverse services which include complete Day Spa packages, Acupuncture, Reiki, Reflexology, Far Infrared Sauna Treatments, Endermologie, Thai Stem Massage, Hot Stone Massage and much more.
Enter our site to explore the many treatments that await you. We look forward to sharing our experience and energy with you.


text: I am so angry about how my antidepressant was prescribed to me. My general practitioner Dr treated these drugs as though they were benign, Looking back, I became unreasonable on 2 meds, prescribed at 2 separate times. I feel this all contributed to fetal demise that occurred. I want to write my Dr. a letter to explain my anger, and to request this Dr to be aware of the significance of these meds and to insist pts see a psychiatrist for correct med evaluation. My question is this, Do you think this will help me with my anger and grief. I'm so angry that I was treated so carelessly. This has affected my life so much.


text:
McClintic and Hoffman Re-Elected to the PSRS/PEERS Board of TrusteesApril 16, 2014
Incumbent Board members Susan McClintic and Jason Hoffman, whose current terms on the Public School and Education Employee Retirement Systems of Missouri (PSRS/PEERS) Board of Trustees end June 30, 2014, were the only individuals to file for two open Board seats. Since they were the only two candidates certified for the vacancies, they were automatically elected. Had other candidates filed, an election would have been held in April.
Both will begin their new, four-year terms on July 1, 2014, and serve through June 30, 2018.
"The Board is very pleased that Jason and Susan have been elected to serve new four-year terms," says Dr. Aaron Zalis, Board chair "Their knowledge and experience continue to add value and help ensure retirement security for our members."
Susan McClintic, an educator for Columbia Public Schools, was first elected to the Board July 1, 2010. She has more than 23 years of teaching experience and currently serves as president of the Columbia Missouri National Education Association (MNEA). McClintic previously served on the board of directors of Susan G. Komen for the Cure and on the Rocheport Historical Society Board of Directors.
Jason Hoffman was also first elected to the Board of Trustees July 1, 2010. Hoffman is currently the chief financial officer for the Jefferson City Public School district. Previously, he served as business manager for both the Hallsville R-IV and Centralia R-VI school districts. Hoffman is a past president of the Missouri Association of School Business Officials (MoASBO).
The Board Election Process
Individuals interested in running for these Board seats were asked to obtain petition forms from PSRS/PEERS and return them by February 17, 2014, along with 200 or more member signatures from each of any four Missouri congressional districts, plus sufficient additional signatures to total at least 1,000. All active and retired members of PSRS and PEERS are eligible to sign petitions and vote for candidates.
An auditing committee comprised of representatives of various Missouri educational associations examined the petitions February 24, and certified to the Board that McClintic and Hoffman were qualified candidates.
Board Re-Elects Zalis Chair; Hoffman Vice-Chair
At the April Board of Trustees meeting, the Board demonstrated continued confidence in its current leadership. They re-elected Dr. Aaron Zalis, superintendent of Rolla Public Schools and an elected PSRS member, to serve as chair. The Board also re-elected Jason Hoffman, chief financial officer for the Jefferson City Public School district and an elected PEERS member, to serve as vice chair. Both will continue to serve in leadership positions for the school year beginning July 1, 2014 and ending June 30, 2015.


text:
The wire and cable industry has been increasingly plagued with theft throughout the last several years. Developing a solution that prevents this from continually occurring can be surprisingly challenging. With that in mind, Southwire has engineered a method to help prevent and track copper wire theft. Though there are many copper theft-deterrent products on the market, most of them fail to provide the proof of ownership that is available in Southwire's Proof Positive Copper and Proof Positive Copper-Clad Steel grounding products.
Southwire's Proof Positive copper is able to be traced back to the owner of the product due to the laser etched Trace-ID codes, located on the center strand of the product. When these codes are typed into the Proof Positive online database (www.2idcu.com), ownership data is available to be used for verification of the product. Everyone has access to this real-time data base including utilities, recyclers, and law enforcement agencies. With this product there is also a long-term theft deterrent system in place. The tinned outer and center strand distinguish it from other bare copper and copper-clad steel cables. Visual identification is key to alerting recyclers that the product has likely been stolen and also serves as a theft deterrent. Also, the steel core of Proof Positive Copper-Clad Steel is harder to cut and has lower scrap values than bare copper.
Through Southwire's involvement, including the End Copper Theft initiative, authorities have more evidence and can prosecute copper thieves easier. Charges are not placed on the thief for the cost of the copper stolen, but for the replacement value; in most cases, there is a substantial difference between the scrap price and the replacement value for the stolen copper. For example, thief taking the stolen copper to a scrap yard will fetch around $2.30 per pound in South Carolina. However, the cost of repairing and replacing the affected products can be more than five times the cost of the stolen material due to labor and material purchases (http://www.nbclosangeles.com/news/local/Menifee-Residents-Furious-Over-Copper-Theft-Power-Outage-204778781.html).
Aside from the monetary implications of copper theft, many people involved do not inherently know the risk. There have been cases where people were harshly burned or even killed by electrical shock. Wire theft also causes power outages, often effecting more than just a few businesses and residential areas. One incident from April 25, 2013 in Riverside County California left 22,000 people without power for several days.
In order to avoid these types of situations, Southwire has created EndCopperTheft.com and Proof Positive Copper in hopes of making copper theft less appealing to thieves. To learn more about Southwire's end copper theft initiative, visit http://www.endcoppertheft.com/.
Additional resources:
– Fernando Baldizon


text:
Call us 7 days a week
Tennsco All-Welded Ventilated Lockers Offer Security, Visibility And Maximum Air Flow.
Tennsco All-Welded Ventilated Lockers are constructed of high strength steel for long lasting durability. Locker doors and sides are ventilated for maximum airflow and complete visibility of contents. Locker doors swing on knuckle hinges for smooth, precise operation. Available types are Single Tier with vandal resistant recessed handle, three coat hooks, one coat rod and one top shelf per opening, Double Tier with vandal resistant recessed handle and three coat hooks per opening and Six Tier with padlock hasp latch (lock not included). Color finishes are Medium Gray and Sand. Dimensions vary by model. Lockers are not returnable.
Give Us Your Feedback On This Page
* Help us continuously improve by reporting any errors or omissions on this page including:


text: Are you in need of an affordable yet professional center to handle your customer calls? Angeles City Call Center provides the best of both worlds. We're a western owned and managed call center located in the heart of the Philippines to ensure your costs are low without while being able to uphold western standards of practice. Contact Us For as little as $150 per month per workstation, you can now lease an office space in our building! Our turnkey services provide everything that your business needs, all in one place. You can start making calls for your campaign on day one, it's that easy. We currently have 100 seats available for lease, all of which have been fully equipped with brand new cubicles, quad-core computers, flat screen monitors, top quality headphones, and a reliable connection to our lightning fast dialers. Our office also features private office cabins, a fully-equipped kitchen/break room, and video conferencing rooms. What's Included? Agent Stations: Each of our workstations has been optimized to promote productivity and comfort. The agents are provided with all the hardware necessary to keep efficiency levels at maximum. 20"x30" desk space PC's with I7 processors Noise canceling headsets 21"LG Monitors Cozy chairs LDKai Mice LDKai Keyboard Vici dial system IT Infrastructure: Constant assessment and improvement is commonplace inside the Angeles City Call Center office. We want to make sure that our IT infrastructure remains secure, our bandwidth uncongested, and our connections are fast, so that we not only meet your business' needs but exceed them as well. Security Fast Internet Efficiency Capacity Facilities: We want to make sure that everyone inside our office feels safe, comfortable, and stress-free. This is why we have invested a lot of time, effort, and money in planning the layout and purchasing all the equipment necessary to achieve such workplace. Our efforts have resulted in smooth business operations that our clients love. Full time IT staff Full time QC staff CCTV Cameras Large training room Back up generator 10,000Sqft facility Full time Admin staff Air Conditioning Fun and Games:


text:
Look 4 a full stack php developer for lots of job
Бюджет $10-500 USD
Hi , my name is Shawn and I am a CEO of IT agency in south Korea
I am here to find a full stack php developer who can design well.
I already have a desktop app developer and android developer but I don't have a php web developer.
I have met so many scammers who lie and try to cheat and has a bad skill in this site
and I have went to dispute so many times with them.
I am tired of fighting with scammers here and freelancer.com doesn't refund the project taken fee.
so I decided not to hire stranger before I work with him
So you must finish my project first then I will hire you.
When you show me the finished project then I will hire you and create milestone.
You don't have to worry about what if I wouldn't hire you after you spent a lot of time and effort.
Because I will check your work everyday and I would say "Please stop" if I don't like your job or communication.
So if you continue the job then It means I will hire you .
If you agree with my suggestion, please write " I will finish your project first before you hire me and show you the web in my server then you can hire me"
in your application form.
If you change your words, I would be mad so I might swear you.
So do not write "I will finish your project before you hire me" if you don't agree.
I can't put enough money for this project but I can promise you that I will hire you with better budget with another project.
Build a responsive web for tutors and students
- Reference web : http://freelancer.com( Simple version, no payment system)
- Current my website: [login to view URL] (Doesn't have 1 on 1 realtime chat/rate/review/bidding system)
- Responsive web
- PHP core(No CMS) for web
- Mysql for Database
- Node.js for chat
[login to view URL]
- Verify email
- Save user's ip address and time when register
[login to view URL]
- Save user's ip and time when log in
[login to view URL] board
- My project and news feed for user
[login to view URL](1 on 1 real time chat)
- Same chat system as freelancer.com
-Show online/offline
-Show red mark for unread message
-Show message order by recent
[login to view URL] start ticket
- Employer can start chat but tutors can start chat limit
- when tutor sign up ,they get 5 times chat start ticket
- When tutor get hired they earn 10 chat start ticket
[login to view URL]
- Show red mark for unread notification
[login to view URL] jobs
- Searching option
- Bidding system( Show the list of bidder order by their rate)
- Hire and accept and close automatically within certain days
[login to view URL] tutors
- Searching option
- Order by rate
[login to view URL] lanuage exchange partner
[login to view URL] board
[login to view URL] post
- Given sample post form
- Open 7days then close automatically
- Award system
- Email and notification reminder for leaving review(If it is awarded)
[login to view URL] user
[login to view URL]
- Review & Rate
- Edit profile
- Upload profile image
Admin page
[login to view URL]
- 5 new users
- 5 new posts
- 5 new comments
2. member list
- edit/delete member
[login to view URL] list
- edit/delete post
[login to view URL] list
- edit/delete comment
[login to view URL] user
10 фрилансеров(-а) в среднем готовы выполнить эту работу за $324
hi Shawn, I am fully stacked experienced and skilled PHP developer, I would love to assist you in web designing You can see my previous work, we can discuss more in the message. Relevant Skills and Experience I am ex Больше
Hi, I've carefully read you long job post. I have a extensive knowledge of php from 14+ yrs experience in this sector. Relevant Skills and Experience PHP, Frameworks Proposed Milestones $283 USD - Deliver
I am a full stack php developer and i can design very well as per the clients requirement and demands. Relevant Skills and Experience I have a total of 12 years of experience in MySQL, node.js, PHP Web Designing and Больше
Hi, I can provide you some of feature: Chat box (node) Comment, rate, report (node) Bidding system (java) Login (email and social), register, forgot password (java) regards, Relevant Skills and Experience Java, node.j Больше
I am a skilled and experienced developer. I have developed couple of similar web portals and I am confident that i will do this project. I also have similat experience that is why I will not work until you hire me. Bu Больше


text:
Every couple wants their guests to have a great time at their wedding, but there's always the chance that a guest will enjoy themselves a little too much and over-indulge at the bar. Not a big deal — unless getting to and from your wedding involves driving a car. If you have a guest with a set of keys who is in no shape to drive, what should you do? Here's some advice from our experts to help keep everyone safe.
If you're worried that one of your guests isn't fit to get behind the wheel of a car, don't be afraid to speak up. Start by finding whoever they arrived with, whether it's a spouse or significant other or a group of friends. Recruit them to help you handle the situation: It's much easier to address when you've got a few people on your side. If any of them are sober and comfortable driving, ask them to take the keys and get everyone home safely.
Did the guest in question arrive alone, or with other people who also aren't fit to drive? This is where Uber or a local taxi service comes in. Confirm with your venue that the guest can leave their car overnight (and make sure they let any night staff and those working the next morning know that the lone car in the lot is okay), then arrange a ride home for your inebriated guest. Be sure to text them or leave a voicemail letting them know where there car is, in case there's any confusion in the morning.
Worried about even putting your guest into the back seat of a car? Find a quiet space, such as that couch in the lobby, where they can rest and collect themselves before you send them home. No matter the situation, be sure to provide your guest with something to eat and lots of water to start hydrating, hopefully putting a little bit of a dent in the hangover they'll have tomorrow.
See more: What Should You Do If a Bridesmaid, Groomsman (or You!) Gets Drunk Before the Wedding?


text:
Critical Section
Archive: January 3, 2010
<<< January 2, 2010
January 4, 2010 >>>
time to start the new year
Sunday, 01/03/10 09:22 AM
Good morning! I slept for 10 hours last night, crashed while watching a football game, and didn't move one muscle after that. Guess I needed it... anyways it is a beautiful day, albeit a little windy; a good day for de-Holiday-ifying; the lights are coming off the house, the tree is being un-decorated and dragged to the curb, and my todo lists are being updated. Fortunately I have *energy* coming out of the 200K yesterday. Still buzzed and happy. Ultracycling isn't for everyone but I must tell you it has a definite magic; there's the physical exercise of course but also the mental flossing, and the feeling you have about yourself and the world after you finish a long ride cannot be matched...
So what do you think, will 2010 be better than 2009? Instapundit is running a poll, and right now "worse" is winning, 40% to 28%... that surprises me, people are usually optimists even when they don't have reason to be. I suspect Obama's steep fall from grace is a factor. Personally I think 2010 will be better, for undefined reasons...
Some weird looking ahead: TechCrunch predicts the top ten digital M&A deals in 2010. I don't see some of these at all; Cisco acquiring LinkedIn?
Some weird looking ahead: TechCrunch predicts the top ten digital M&A deals in 2010. I don't see some of these at all; Cisco acquiring LinkedIn?
Why tending topics are spectacularly useless. And by implication, why "realtime search" results from Twitter are a fad. I *still* don't get it, I'm trying, honestly I am, but everytime I try to read Tweets from anyone my brain turns to mush. BTW as Facebook becomes more like Twitter, it is becoming less interesting. Have you noticed this too?
Cool space story of the decade: Mars rovers begin year seven on red planet. Who knows, maybe they'll be the cool space story of the next decade, too. In addition to being cool, they've been useful; here's a nice overview of what we have learned from the Mars Rover missions.
Okay, enough blogging around; time to start the new year!
Sunday, 01/03/10 01:58 PM
Lights down, tree undecorated and out, garland out, reindeer garaged, decorations packed, and gnome [carefully] stowed. Record time (a team effort). Onward into the decade.
Rockstore! (the video)
Sunday, 01/03/10 10:43 PM
Return to the archive.
About Me
Greatest Hits
Correlation vs. Causality
The Tyranny of Email
Unnatural Selection
Aperio's Mission = Automating Pathology
On Blame
Try, or Try Not
Books and Wine
Emergent Properties
God and Beauty
Moving Mount Fuji
The Nest
Rock 'n Roll
IQ and Populations
Are You a Bright?
Adding Value
The Joy of Craftsmanship
The Emperor's New Code
Toy Story
The Return of the King
Religion vs IQ
In the Wet
the big day
solving bongard problems
visiting Titan
unintelligent design
the nuclear option
estimating in meatspace
second gear
On the Persistence of Bad Design...
Texas chili cookoff
almost famous design and stochastic debugging
may I take your order?
universal healthcare
triple double
New Yorker covers
Death Rider! (da da dum)
how did I get here (Mt.Whitney)?
the Law of Significance
Holiday Inn
Daniel Jacoby's photographs
the first bird
Gödel Escher Bach: Birthday Cantatatata
Father's Day (in pictures)
your cat for my car
Jobsnotes of note
world population map
no joy in Baker
vote smart
exact nonsense
introducing eyesFinder
to space
where are the desktop apps?


text:
Will someone please go to FedEx headquarters and give them a wedgie? They need something to wake them up. They are killing the Kinko's brand and replacing it with FedEx Office. 1. Great brands are priceless and irreplaceable. You can't create a great brand. You earn it with decades of marketing, customer service, and great […]
Tag Archives: Kinko's
Brand Suicide
November 23, 2008
Get My Newsletter
We will never, ever release your email.
*Third-party newsletter (Privacy Policy)
*Third-party newsletter (Privacy Policy)
Recent Posts
Work With Me
Learn to get people talking about your company, cause, or idea.
Learn more >>
We're the community for social media leaders at the world's greatest brands. Learn more >>
Learn about my keynote speeches >>


text:
Translink puts forward a plan that is sensitive to taxpayers' concerns that expensive, new train infrastructure may not be the best at serving our transportation needs and it is worth to examine how our existing bus lines can be utilized more efficiently.
Among the obvious solutions to help transit buses negotiate city traffic is to ban bicycles from bus routes.
At the same time the City should expand the network of bicycle routes on residential streets.
Currently a single cyclist moving slower than 15 km/h is slowing down more than 50 commuters on a bus capable of traveling three times faster.


text:
I received sick of asking yourself, is my blade as sharp as it could be? So I designed a jig for that! Now I do know that each blade isn't always Ideal at 30 degrees, however it's an incredible starting point. The adjustment screw is often a thread an.Flip The strain lever back to tighten the new belt and utilize the tracking knob so it operates ce… Read More
^ "Dewalt, bringing you retarded engineering For the remainder of time". I truly like my 718, given that my helper is close to to obtain it to the stand for meor Ask for a quote New flooring and mouldings could become a place's point of interest and remodel your decorPosts: 618 Rewards Factors: 764 Re: DW717 Vrs DW780? I had been again up at the … Read More
Your best wager is to select a whey powder that contains whey protein hydrolysates (whey protein broken down into scaled-down fragments for quicker digestion) or whey protein isolate.Vitamin B intricate designed our checklist of excellent weight gain supplements primarily thanks to its job in Electrical power production. Opposite to popular impress… Read More
This vasodilation leads to remarkable muscle "pump," in addition to speedier Extra fat loss, states "Normal Anabolics."This ingredient is usually characterised via the flushed deal with sensation Which might be accompanied by tingling when ingested.We have been capable to see seen and measurable outcomes rapidly. And we currently felt a major Chang… Read More
If This really is your internet site, sign up and get Accredited to acquire direct measurements of your web site's visitors.have ample information to estimate these metrics. If this is your site, enroll and have Qualified to receive direct measurement of your web site's targeted traffic.Hold up-to-date with all things Lomography! Subscribe to … Read More


text:
A Meditation Mat
A Meditation Mat is located in Crimbo Town
Meditation Mat
- On first visit:
You sit down on the mat and close your eyes, attempting to meditate on your bung. You feel really silly about this at first, but eventually you manage to push that feeling away -- after all, it's probably not the silliest thing you've ever done in your adventures. You breathe deeply and slowly, and clear your mind of all thought.
At first, everything is dark. Not a scary darkness, merely an absence of light and all other stimuli. Everything is very still and calm. Then, a hazy, indistinct outline begins to appear. As you focus on it, it resolves into a silhouette of your own body, as though you're seeing it from above. A dim red light flickers at... well, at the bottom, right where you might've guessed your Bung chakra would be located. The light is obscured by writhing shadows -- presumably the spiritual "gunk" that Tammy said you needed to clean out. Fortunately, it looks like you can solve this problem the same way you solve pretty much every problem you encounter: by fighting it.
- After cleaning all chakras, next adventure in Your Hat Chakra:
Back in the days when the workings of the body and mind were so poorly understood that barbers were doing surgery, people attributed all these constant mental naggings about old embarrassments and mistakes to a little invisible demon that rode on your shoulder, whispering terrible things in your ear to make you crazy. Nowadays, we know that the culprit is actually just your own brain, being a huge jerk for no good reason.
Time to show it who's the boss around here. You're fighting Your Brain.


text:
Most design work is charged at a flat rate, as opposed to hourly. Comparing different hourly rates among potential designers or firms is not apples to apples. Ask for an estimate for a particular job, not about hourly rates in general.
Prior to requesting an estimate from a potential designer/firm:
- Review their portfolio: It should be available online. Do they have repeat clients? Do they have the expertise you are looking for? Do they have testimonials from clients they've worked with?
- Ask about their creative process: Are they simply order takers who will blindly do whatever you tell them even when they think it's not the best route, or do they act as your partner and provide professional opinions and guidance, allowing you the option to take it or leave it?
- Gauge how responsive they are via phone or e-mail with your initial contact (and later as well): Do they have normal business hours and respond promptly, if at all? How long will it take to get a first proof or to make minor text changes throughout the process? Calling the designer or firm to ask questions can also be a great way to see if you both might be a good personality match, which can play a role in working with someone.
- Ask for references: Once you have references, find out what the client's experience was/has been with respect to attention to detail, staying within budget and on schedule, the type of work you are seeking to have done, knowledge of the industry, etc.
If the designer or firm seems to be a good fit, request an estimate for your next project. Be sure to check the terms about the number of designs, number of drafts or time allotted for revisions, and even what constitutes a "revision" (typically anything deviating from the content you originally submitted) so you can manage your expectations. You don't want to end up spending money on unforeseen expenses or incurring additional time into your schedule—


text:
- Research
- Open Access
Innovation by patients with rare diseases and chronic needs
© Oliveira et al.; licensee BioMed Central. 2015
- Received: 25 November 2014
- Accepted: 20 March 2015
- Published: 9 April 2015
We provide the first empirical exploration of disease-related innovation by patients and their caregivers. Our aims were to explore to what degree do patients develop innovative solutions; how many of these are unique developments; and do these solutions have positive perceived impact on the patients' overall quality of life? In addition, we explored the factors associated with patient innovation development, and sharing of the solutions that the patients developed.
We administered a questionnaire via telephone interviewing to a sample of 500 rare disease patients and caregivers. The solutions reported were pre-screened by the authors for their fit with the self-developed innovation aim of the study. All the reported solutions were then validated for their novelty by two medical professionals. Logistic regression models were used to test the relationships between our key variables, patient innovation and solution sharing.
263 (53%) of our survey respondents reported developing and using a solution to improve management of their diseases. An initial screening removed 81 (16%) solutions for being an obvious misfit to the self-developed innovation aim of the study. This lowered the sample of potentially innovative solutions to 182 (36%). Assessment of novelty and usefulness of the solutions, conducted by two medical evaluators, confirmed that 40 solutions (8%) were indeed novel, while the remaining 142 (28%) were already known to medicine. The likelihood of patient innovation increased as the education level increased (OR 2, p < 0.05), and as their perception of limitations imposed by their disease increased (OR 1.3, p < 0.05). 55 individuals diffused their solutions to some degree, with 50 of these sharing via direct diffusion to other patients. There is a positive relationship between the impact of a solution on the respondents' overall quality of life and likelihood of solution sharing.
Given that hundreds of millions of people worldwide are afflicted by rare diseases, patient and their caregivers can be a tremendous source of innovation for many who are similarly afflicted. Our findings suggest that many patients could be greatly assisted by improved diffusion of known solutions and best practices to and among patients and their caregivers.
- Patient Innovation
- User Innovation in Health
- Diffusion of Innovation
- Rare Diseases
There are 5000 to 8000 rare diseases which, taken together, afflict up to 8% of the world's population [1,2]. Most are genetic and chronic, and many impose significant difficulties on the daily lives of both patients and their caregivers [3]. Patients with rare diseases also tend to be underserved both clinically and scientifically [4]. Small market size, due to each diseases' low prevalence, makes it commercially unattractive for pharmaceutical firms and other medical suppliers to invest in developing new products specifically for rare diseases [5].
High patient need coupled with low commercial activity in rare disease marketplaces creates both a need and an incentive for patients and their caregivers to innovate for themselves to help them with respect to many quality of life issues. Studies of innovation by citizens show that useful innovation by patients to serve their own needs is likely: many citizens have been found to develop and improve products for their own use in a wide range of fields, including medical care needs [6-8]. Indeed, individuals with high and unmet need for a solution often develop a solution/product for their own use before a producer introduces an improved version of the product to the market [9,10].
An increasing stream of literature argues for a more prominent role of patients and caregivers in healthcare delivery [11-14]. However, this literature does not yet consider the innovation capacity of patients and caregivers. Recent qualitative research has found that patients and caregivers are not only the drivers of institutional research [15], they invent a myriad of valuable solutions to improve their own personal medical situations. These solutions span from simple tools for everyday use, through discovery of previously unknown therapies, to highly sophisticated solutions. An example of the latter is a textile mesh support for dilated heart aorta developed by a Marfan syndrome patient [16,17]. Emergence of innovation intermediaries in healthcare [18], and initiatives to discover and share patients' solutions (like www.patient-innovation.com) suggest that the awareness of patients' innovation capacity is increasing. Still, there is a dearth of quantitative academic research related to patient innovation.
Patients and their caregivers who develop solutions to address some of their disease related problems can potentially give valuable contributions to the stock of knowledge about their diseases and ways to cope with them. The general value of these solutions increases if the solutions diffuse. Our objectives in this study are to explore: to what degree do patients develop innovative solutions; how many of these are unique developments; do these solutions have positive perceived impact on quality of life; and, whether the patients share their solutions and how. With this paper, we aim to provide evidence of the rare diseases patients' innovation activity, and propose paths for further research on this important topic.
Data collection
We conducted a survey of patients with rare diseases with the support of an association of mental deficiencies and rare diseases located in Europe. The association has about 800 patients registered as its members and runs a help-line to support patients inquiring about administrative and disease related issues. The association documents all contacts, and together with the information on members has records of about 5000 individuals who had contacted its help-line in the period from 2009 until the end of 2012. From these 5000, the association's staff randomly selected a sample of 1000 individuals for us to contact.
Four, trained social workers with extensive experience in working with rare diseases patients within the helpline, were appointed by the Association to administer our survey. To familiarize these individuals with the content of the survey and goals of initial testing and validation of the survey, our research team organized two training meetings, and conducted two testing/validation sessions to adjust the survey to the targeted population and clarify interpretation. The interviewers contacted individuals on the association-supplied list in sequence, continuing until we had obtained completed questionnaires from 500 subjects.
Interviewers began each telephone interview session by identifying the participating organizations and explaining the purpose and topic of the survey. They proceeded to the questionnaire itself only after receiving the subjects' consent to participate. The interviewers made 546 calls to the patients from the help-line's contact list, to gather 506 responses (93% response rate), of which 500 were usable for further processing. Average call duration was 32 minutes, with calls taking anywhere from 10 to 90 minutes. All the information collected by the interviewers and included in the dataset for analysis was de-identified. Patient data was analyzed as a group with no individual disclosure of classified information according to the Helsinki Declaration for human studies. Local ethics committee (Comissão de Ética do Centro Hospitalar Lisboa Norte" (Ethics Commission of the Center of Hospitals in the North Lisbon)) gave their approval for the content of the survey. The data used in this paper, from the survey and other sources, are described in Additional file 1: Table S1.
Our survey was partitioned into 7 sections. It contained 67 questions in total. All were grounded in user innovation literature. In the first section, we identified the respondents as patients or caregivers, and adapted the language of the questions that followed accordingly. We next asked about the limitations imposed by the patient's disease upon both patients and caregivers. We then asked about perceived needs for health-related solutions, and asked whether the patient or a caregiver had developed a solution that helped them cope with the patient's disease. Depending on the answer, respondents were branched to one of four sections; (2) no solution developed; (3) equipment or technical aid development (4) therapy development; or (5) a behavioral change developed. Respondents with developments were then asked to describe what they had developed in detail. To estimate the value provided by their solution, respondents were also asked to estimate their overall quality of life before using their solution, and after using it. We used a single-item, 7-point Likert Scale to measure the quality of life. If the respondent was a caregiver, quality of life changes for both the caregiver and the patient were asked about. The 6th section asked questions about respondent demographics, and the 7th asked about respondents' use of the Internet and medical community memberships.
We applied a two-step procedure for assessing the novelty of the solutions. In the first step, the authors of the paper removed solutions that were an obvious misfit to the aim of the study. After the initial screening, assessment of the novelty of all the solutions developed by the respondents was conducted independently by two Ph.D. medical professionals, who each had both clinical and research expertise. These individuals had available the information about the disease and its duration, the patients' gender, and hand-collected descriptions about each of the 251 diseases identified in the sample. In addition, two research assistants collected information about common therapeutic practices for the diseases. Each clinician-evaluator independently read through the patient solution descriptions and, based upon their expert medical knowledge, evaluated whether respondents' novelty claims were correct, or whether the solution was already known to them or the medical practice for the disease. While evaluating they checked the medical literature and the information collected by the research assistants. The two expert evaluators had very good inter-rater agreement (kappa = 0.81). Only when both agreed that a solution was novel did we code the solution as a patient innovation. If the solution was already known to medicine, although not to the respondent describing it, the solution was coded as a redevelopment. Redevelopments are of value to individual patient developers who obtain the use of a pre-existing solution in this way, but do not add to the stock of available medical knowledge – they are not new to the world. We also asked the evaluators to assess all the solutions and judge whether in their opinion the solutions are useful or helpful for the patients. Together with the evaluators, we established three criteria to assess the solutions' usefulness/helpfulness: (i) it helps the patients or caregivers in their daily activities; (ii) it may help in coping with the disease; and (iii) it is a cost saving alternative to something that already exists. The evaluators were asked to give one general assessment of the solutions as useful or not-useful, based on these three criteria. In addition, the evaluators indicated which of the solutions they considered to be dangerous.
Data analysis
Socio-demographic characteristics of the respondents
Respondent's Age (years)
Disease Duration (years)
University Degree
SD = standard deviation
We built another model to test the likelihood of information disclosure. Beside the variables from the first model, we added one variable to this model: the difference in the overall quality of life between the reported values for the periods before the innovation and after the respondent used the solution; the quality of life for the two time periods was measured on a 7-point scale, from 1 – extremely low, to 7 – excellent. We conducted the analysis using two data samples: 1) full-sample with 263 reported solutions; and 2) restricted sample with 182 solutions that passed the pre-screening. The rationale for including the both samples is the following: for studying the solution sharing activity, what matters is whether the respondents believe that they have developed something; to check the robustness of the results, we included the analysis using the restricted sample.
We presented our results as raw coefficients in the tables, together with robust standard errors. Continuous variables are expressed as mean and standard deviation and discrete variables as absolute frequency. In the text, we report odds ratios and 95% confidence intervals as measures of effect. Significant p-values were set to <0.05. Stata 13 software was used for data analysis.
Population included in our study
Respondents' socio-demographic characteristics are described in Table 1.
As can be seen, the majority of the 500 respondents in our sample were caregivers (59%), and 85% of the respondents were women. Women also constituted 65% of all the patients in our sample.
The average age of patients in our sample was 33 years, with a standard deviation of 22 years, while the average age of the respondents was 45 years with a standard deviation of 13 years. 65% of the respondents were between 18 and 45 years old. The disease duration was 12 years with a standard deviation of 12 years. One-third of the respondents held university degrees, 51% were employed, and 64% were married or in de facto unions.
The extent and types of patient-developed innovations
263 (53%) of our 500 respondents reported having developed a solution they regarded as novel to assist them in managing their disease. The initial screening removed 81 solutions, leaving 182 (36% of 500) potentially novel solutions. Further evaluation by the expert medical evaluators suggested that the solutions of 8% of our respondents were also evaluated as novel – "new to the world" – by our expert medical evaluators. The remaining claimed innovations that passed the initial filtering were judged by our expert evaluators to be redevelopments – novel to the patient developer, but already known to medicine. In the following tables we use the restricted sample of 182 reported as novel solutions that passed the initial screening, unless otherwise indicated.
Type, novelty, and usefulness of reported solutions
Novel to the patient (% of 142)
Novel to the world (% of 40)
Total (% of 182)
Dangerous (% of 4)
Not useful/helpful (% of 105)
Useful (% of 73)
4 (3%)
15 (37%)
19 (10%)
4 (4%)
15 (21%)
138 (97%)
25 (63%)
163 (90%)
4 (100%)
101 (96%)
58 (79%)
Total (% of 182)
142 (78%)
40 (22%)
182 (100%)
4 (2%)
105 (58%)
73 (40%)
Examples of the solutions
Most of the solutions in our sample are technically very simple, but nonetheless offer great value to patients. Consider the case of a mother who takes care of her son, an Angelman syndrome patient. Angelman syndrome involves ataxia, inability to walk, move or balance well. The mother experimented with many strategies, recommended by the doctors, therapists, or found elsewhere, but obtained little gain for her child. By chance, at a neighbor's child's birthday party, she noticed her son excitedly jumping for strings to catch a floating helium-filled balloon. This gave her an idea and she experimented at home by filling a room with floating balloons. She found her child began jumping and reaching for the balloons for extended periods of time, amused by the challenge. The mother also added bands to support the knees and keep the child in an upright position. The result was significant improvement in her child's physical abilities. Other parents to whom she described the solution also tried the balloons strategy and had positive results. This was valued as a novel solution by the medical evaluators.
Consider now a mother of a kid with cerebral palsy. This disease, among other manifestations, makes the kid to hyper salivate. Besides being a discomfort and a potential source of disease, the hyper salivation is also a cause for social exclusion. The medical solution for this problem - removing the salivary glands - is considered by this mother as too drastic and with very limited benefits. Instead, she tried solving the problem by considering strategies that allow her son socializing more easily with other people. She developed "The Cute Turtle Collar", a kind of a turtle collar piece made of a material that absorbs well the slobber, and is both stylish and suitable to use in all weather conditions.
Several of the reported solutions included descriptions of intensive physical activity, which, according to the respondents, led to moderate improvements in their overall quality of life. Daily practice of martial arts, Muay Thai and kick-boxing up to 5 hours a day, is an uncommon choice for a Trombocitopenic purpura patient. The patient opted for this sort of exercising contrary to the advice of health professionals not to engage in physical activities that could hurt the body. The respondent reported significant decrease in frequency of hemorrhages, which she associates with the intensive practice of martial arts.
Another case from our sample, that also involves intense physical activity, is of a boy afflicted by Charcot-Marie-Tooth disease. This disease makes the patients progressively lose muscle tissue and touch sensation, and often the first visible symptoms of the disease appear in legs and hands. The boy's daily practice of playing piano has slowed down the disease's development in hands and masked some of the symptoms, which made the diagnostic process harder. He continued playing the piano, and the hands remained fully functional, with little or no sign of the disease, while he may need a foot surgery to maintain the desired level of functionality. Benefits of physical exercise are well-known, but, in this case, the intensity of the exercise may have changed the development of the disease. This information may be useful for medical professionals in establishing a correct diagnosis for similar cases earlier, and also as a strategy to be considered by other patients and caregivers.
The vast majority of the innovations in our sample have been developed to increase the patients' autonomy. For example, a patient with Myasthenia gravis, an autoimmune neuromuscular junction disorder, reported designing several products custom-built according to her specifications. She described a design of one of the tools – a metal two-hook button aid that helps her button pants without assistance of others. Although an online search quickly reveals variety of button hooks, patients, as is the case described, often experiment with the design to make the one that better fit their specific condition and needs. Other solutions reported involved experimentation with the design of elements commonly found in any household; for example, optimization of the height and width of stairs to improve mobility, or design of tables and chairs with added features to increase safety of hyperactive children with cognitive limitations.
The impact of the solutions
Perceived difference in overall quality of life after using the solutions
New to the respondent
New to the world
Quality of life difference
Quality of life difference
Nr. of cases
Mean (SD)
2.2 (2.2)
0 (0)
2.2 (1.5)
1.7 (1.4)
Nr. of cases
Mean (SD)
1.6 (1.5)
1.5 (1.5)
1.8 (1.4)
2 (1.7)
Nr. of cases
Mean (SD)
1.6 (1.5)
1.4 (1.5)
2 (1.4)
1.9 (1.6)
Quality of life improvements resulting from using the innovations were significant (p < 0.001, two-tailed t-test). The difference in quality of life improvements was not significantly different (p < 0.21, two-tailed t-test) in the case of innovations that were new to the individual patient/respondent compared to new to the world.
Perceptions of the solutions' usefulness by patients and medical professionals
Reported (by respondents) improvements in overall quality of life (QoL)
No change in QoL
QoL improved
Total (% of 167)
Medical professionals' assessments
3 (2%)
Not helpful/useful
96 (57%)
68 (41%)
Total (% of 170)
52 (31%)
115 (69%)
167* (100%)
The extent and type of solution diffusion
The patients' solution sharing activities
Non-restricted sample (n = 263)
Restricted sample (n = 182)
Solution sharing activity
New to the world
New to the respondents
New to the world
New to the respondents
(n = 19)
(n = 65)
(n = 19)
(n = 36)
Shown it to other patients
Shown it to medical professionals
Shared the info on a website/blog/social network
Shared it through media
Shown it to commercial entities
Spent time and/or money to help others (people, companies) use the solution
Made a manual or documentation that helps using the solution
Considering the full-sample, the most common mode of sharing was patient-to-patient, reported by 74 individuals – 88% of those who shared a solution. Interestingly, only 5 individuals - 6% of the respondents who shared solutions – shared their solutions with their doctors. Sharing with commercial firms occurred in 3 cases. In four cases, patients or caregivers spent time or money to help diffuse their innovations. In three of these cases, the developers also reported making a manual or documentation to help others use their solutions.
What influences patient innovation and solution sharing
We next assess factors that are associated with patients' likelihood of developing and sharing their novel developments.
Logit models of likelihood of patient innovation and solution sharing
Non-restricted sample
Restricted sample
Patient innovation
Solution sharing
Solution sharing
Disease prevalence
0.15 (0.15)
−0.13 (0.16)
−0.11 (0.20)
Disease burden
0.27** (0.13)
0.12 (0.14)
0.09 (0.19)
Respondent's Age
0.13 (0.09)
0.25** (0.1)
0.21** (0.11)
Respondent's Age squared
−0.002* (0.0)
−0.002** (0.0)
−0.002* (0.001)
Disease Duration
0.02 (0.05)
−0.07* (0.04)
−0.13*** (0.05)
Disease Duration squared
−0.001 (0.0)
0.002* (0.0)
0.002*** (0.001)
−0.51 (0.42)
−0.25 (0.49)
−0.29 (0.55)
Academic Degree
0.68** (0.3)
0.33 (0.27)
0.37 (0.30)
Employment status
−0.05 (0.38)
−0.13 (0.36)
0.41 (0.44)
Marital status
0.66 (0.4)
−0.01 (0.36)
−0.25 (0.45)
Medical patient community membership
0.39 (0.43)
0.29 (0.44)
0.30 (0.51)
Improvement in overall quality of life (before-after solution use)
0.52*** (0.11)
0.55*** (0.15)
−7.26*** (2.2)
−7.58*** (2.4)
−7.53*** (2.54)
McFaden's pseudo R2
In models 2 and 3 we explored factors significantly associated with innovation sharing. Model 2 included the full sample of 263 reported solutions, while model 3 included only 182 reported solutions that passed the initial screening. The strongest predictor of information sharing was the observed difference in the respondents' overall quality of life before and after using a solution, in both models 2 and 3. A one-point increase in the perceived difference increased odds of sharing the solution by a factor of 1.7 (95% CI: 1.4 - 2.1), everything else held constant (p < 0.01) (model 2). The effect was robust to the change in the sample size in both the magnitude and the statistical significance. Also, we found an inverted U relationship between the age and the likelihood of sharing a solution - the effect of age on the predicted probability becomes negative after the age of 55 (p < 0.05) (model 2). The non-linear effect of age on the solution sharing did not maintain the statistical significance level in the non-restricted sample, although both the sign and the coefficient remained the same (model 3). Also, a major difference between models 2 and 3 is that duration of a disease has positive and non-linear relationship with the solution sharing in model 3, which was not the case in model 2. The instability of the results for the age and disease duration with respect to the solution sharing suggests that further exploration is needed to clarify these effects.
Our first-of-type study has found that 36% of our sample of rare disease patients and/or their non-professional caregivers have self-developed improvements to the management of their diseases and that use of these, significantly improved their quality of life. Our expert clinical evaluators determined that 40 (22%) of these 182 claimed improvements were new-to-the-world. The rest were already known to medicine, although not to the patient or caregivers who redeveloped them.
We suggest that our results have significant implications for all stakeholders in the health care delivery process related to rare diseases. An estimated 6% to 8% of the world's population – hundreds of millions of people - are afflicted by rare diseases. It is known that commercial innovation efforts on these patients' behalf are negatively affected by small market sizes. Our finding that 8% of rare disease patients and/or their non-professional caregivers have developed valuable, new to the world innovations to improve their own care suggests that a massive, non-commercial source of medical innovations exists. It is today largely hidden due to a lack of diffusion efforts by innovating patients, but efforts could be made to change this situation.
Significant positive relationships were found between the limitations caused by an illness, and also education level and likelihood of innovation. Both findings are in line with findings from other studies of innovation patterns among individual citizens [6,7,20]. We also found that the extent of improvement of patient quality of life from their developments is significantly positively associated with efforts to diffuse their innovations to others. Our data uncovered a potential principal-agent problem: patients systematically valuing different innovations than doctors do, as suggested by the observed differences between patient and clinician evaluations of usefulness (Table 4). In further work, we suggest that the sources of this difference should be explored. It is possible, we think, that clinicians assess the usefulness of innovations primarily in terms of whether they affect the clinical course of a disease in beneficial ways. In contrast patients may greatly value innovations that may have no impact on the course of their disease, but that improve their comfort or other aspects of their quality of life while living with their disease.
Recall that we found that most patient improvement development efforts were devoted to re-inventing known solutions of which they were not aware: only 22% of the solutions patients and caregivers developed were judged new to the world by our expert clinician raters. This suggests that information on known solutions, as well as novel ones, is today poorly diffused, and/or that information provided by clinicians is poorly absorbed by many patients. The duration of typical medical appointments are quite limited, and our finding may be due to this. A possibly related finding is that only 6% of patients reported describing their innovations to their clinicians.
Direct patient-to-patient information sharing was the most common mode of innovation diffusion and was reported by 88% of those who shared solutions. The second most common mode of sharing was via blogs/websites/social networks, reported by 25% of those who shared solutions. Rare disease patients and caregivers are known to actively use the Internet and social networks to find and provide help and connect with others patients and caregivers [21,22]. As 85% of the respondents in our sample use the Internet, and of these 71% use social networks, the reported level of solution sharing over the Internet appears low. Non-sharing of potentially useful solutions developed by individual citizens has been identified as a market failure in the user innovation literature [23]. Future research should explore diffusion incentives and effective channels for diffusion, taking into consideration that different age groups may have different requirements and behavioral patterns.
While our sample offers technically simple solutions, patient-developed solutions can also be technically very advanced. As illustration, consider the innovation (not found in this study sample) developed by a hydraulics engineer with Marfan syndrome. This individual had an aortic root aneurysm. Drawing upon his hydraulics engineering background, he developed a personalized external aortic support made from mesh to prevent a progressively enlarging aorta from prematurely ending his life [16,24]. More precisely, the patient assembled a medical and technical team and raised research and development money to further implement and diffuse his innovation. Upon development, his surgeon successfully installed the aortic support, and the clinical advantage was clear. To date, the novel treatment has been successfully applied to more than 40 patients in the period from 2004 to 2014 [25].
Given the novelty and medical value of some patient-developed innovations, as documented in this and other studies, we suggest that further research on this topic should be conducted. It would also be useful, we suggest, to develop and experiment with systems to collect and medically evaluate novel solutions developed by patients, to identify those worthy of further testing, improvement, and diffusion.
Study limitations
This study into innovation development by patients and caregivers has several limitations. First, our sample of patients and caregivers are retrieved from a population of those who have already reached out towards the rare disease association for help via a helpline. These individuals may be more or less likely to innovate than those who did not make contact. Also, our respondents are dominantly women, indicating that female patients or caregivers are more likely to reach out for help through this particular patient association. This creates a modest conservative bias in our findings regarding innovation levels among patients and caregivers.
Second, telephone interviews rather than site visits are likely to understate the level of patient and caregiver innovations that actually exist. Individuals often do not recognize their activities as innovative, or do not report novel developments they make. This limitation makes the observed frequency of patient innovation a lower boundary for the observed population.
Third, self-assessment of satisfaction with a self-developed solution is known to be inflated by the pride individuals take in their self-developed solutions [26]. In addition, our quality of life measure is a single item scale that makes it open to individual interpretation and limits the ability to compare it across different individuals. This item does capture how people feel about their solutions, but caution is needed in interpreting the results.
We found that 36% of our sample of rare disease patients and/or their non-professional caregivers had developed improvements to the management of their diseases that significantly improved their quality of life. Our expert clinical evaluators determined that 22% of these claimed improvements were new-to-the-world, and that the rest were already known to medicine, even if not to the patient or caregivers who redeveloped them. If further research finds that similar frequencies hold for the broader population, the estimated 6% to 8% of the world's population afflicted by rare diseases may collectively offer a tremendous source of information on how to improve patient medical care. Their contributions may complement the efforts by policy makers, research entities, and producers, to help improve the difficult situation of rare disease patients, whose needs for innovations are often underserved.
It is important to continue investigating how rare disease patients and caregivers can be helped in their innovation activity, how innovations can be professionally assessed, and how patient-developed innovations determined to be of general value can be diffused for broader long-term public health benefits.
We are grateful for the funding provided by the Portuguese Science and Technology Foundation (FCT) and the CMU Portugal Program through project CMU-PT/OUT/0014/2009.
Also, we are grateful to Raríssimas, the National Association of Mental and Rare Disabilities, for their support in the data collection; as well as to the medical expert evaluators, and to Pierre Gein, Patricia Pereira and Yuliya Aleksandrova for their assistance.
We thank the anonymous reviewers for their constructive critique and suggestions on how to improve this paper.
Authors' Affiliations
- Rodwell C, Aymé S, eds, "2014 Report on the State of the Art of Rare Disease Activities in Europe", July 2014, European Union. (http://www.eucerd.eu/upload/file/Reports/2014ReportStateofArtRDActivities.pdf).
- Westermark K, Holm BB, Söderholm M, Llinares-Garcia J, Rivière F, Aarum S, et al. European regulation on orphan medicinal products: 10 years of experience and future perspectives. Nat Rev Drug Discov. 2011;10:341–9.View ArticlePubMedGoogle Scholar
- Song P, Gao J, Inagaki Y, Kokudo N, Tang W. Rare diseases, orphan drugs, and their regulation in Asia: current status and future perspectives. Intractable Rare Dis Res. 2012;1(1):3–9.PubMed CentralPubMedGoogle Scholar
- Griggs RC, Batshaw M, Dunkle M, Gopal-Srivastava R, Kaye E, Krischer J, et al. Clinical research for rare disease: opportunities, challenges, and solutions. Mol Genet Metab. 2009;96:20–6.View ArticlePubMed CentralPubMedGoogle Scholar
- Acemoglu D, Linn J. Market size in innovation: theory and evidence from the pharmaceutical industry. Q J Econ. 2004;119(August):1049–90.View ArticleGoogle Scholar
- von Hippel E, de Jong JPJ, Flowers S. Comparing business and household sector innovation in consumer products: findings from a representative study in the United Kingdom. Manage Sci. 2012;58:1669–81.View ArticleGoogle Scholar
- De Jong JPJ, von Hippel E, Gault F, Kuusisto J, Raasch C. The diffusion of consumer-developed innovations: patterns in Finland. SSRN Electron J. 2014:1–30. http://papers.ssrn.com/sol3/papers.cfm?abstract_id=2426498.
- Ogawa S, Pongtanalert K. Visualizing invisible innovation continent: evidence from global consumer innovation surveys. 2011. Available at SSRN 1876186.Google Scholar
- Oliveira P, von Hippel E. Users as service innovators: the case of banking services. Res Policy. 2011;40:806–18.View ArticleGoogle Scholar
- van der Boor P, Oliveira P, Veloso F. Unusual suspects? Innovation by users in developing countries: evidence from mobile banking services. Res Policy. 2014;43(9):1594–607.View ArticleGoogle Scholar
- Dyson E. Why participatory medicine? J Particip Med. 2009;1:1–5.Google Scholar
- Ferguson T. E-patient: how they can help us heal healthcare. 2007Google Scholar
- Hibbard J, Stockard J, Mahoney ER, Tusler M. Development of the Patient Activation Measure (PAM): conceptualizing and measuring activation in patients and consumers. Health Serv Res. 2004;39(4 Pt 1):1005–26.View ArticlePubMed CentralPubMedGoogle Scholar
- Rozenblum R, Bates DW. Patient-centred healthcare, social media and the internet: the perfect storm? BMJ Qual Saf. 2013;22:183–6.View ArticlePubMedGoogle Scholar
- Frydman G. Patient-driven research: rich opportunities and real risks. J Particip Med. 2009;1:6–10.Google Scholar
- Habicht H, Oliveira P, Shcherbatiuk V. User innovators: when patients set out to help themselves and end up helping many. Die Unternehmung. 2012;66:277–94.View ArticleGoogle Scholar
- Oliveira P, Canhão H. Users as service innovators: evidence from banking to healthcare. In: Lakhani K, Harhoff D, editors. Revolutionizing innovation. Cambridge, MA: MIT Press; 2015.Google Scholar
- Kuenne C, Akenroye T, Moeslein K. Online innovation intermediaries in healthcare. In: European Conference on Information Systems (ECIS) 2013 Proceedings. 2013.Google Scholar
- ISO. Assistive products for persons with disability — classification and terminology. Geneve: ISO; 2011.Google Scholar
- Lüthje C, Herstatt C, von Hippel E. User-innovators and "local" information: the case of mountain biking. Res Policy. 2005;34:951–65.View ArticleGoogle Scholar
- Fox S. Peer-to-peer healthcare. Washington D.C.: Pew Research Center; 2011.Google Scholar
- White W, Calhoun C, Holovach J, Marie J, Buchanan L, Sames L et al. Uncommon Challenges; Shared Journeys. Siren Press; 2011.Google Scholar
- von Hippel E, DeMonaco HJ, de Jong JPJ. Market failure in the diffusion of user innovations: the case of "Off-Label" innovations by medical clinicians. SSRN Electron J 2014:1–33.Google Scholar
- Treasure T, Pepper J, Golesworthy T, Mohiaddin R, Anderson RH. External aortic root support: NICE guidance. Heart. 2012;98:65–8.View ArticlePubMedGoogle Scholar
- Treasure T, Pepper J. Personalised External Aortic Root Support (PEARS) compared with alternatives for people with life-threatening genetically determined aneurysms of the aortic root. Diseases. 2015;3:2–14.View ArticleGoogle Scholar
- Franke N, Schreier M, Kaiser U. The "I Designed It Myself" effect in mass customization. Manage Sci. 2010;56:125–40.View ArticleGoogle Scholar
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.


text:
Monday, October 11, 2010
National Coming Out Day
1 comment:
- Armanus said...
Gay rights is just as much a civil rights concern as integration was in the 60's and 70's and really needs to be looked at honestly. Banning gay marriage or service in the military is a reprehensible discrimination, no different then having forced blacks to ride in the back of the bus and give up seats there to whites if the bus got too full.
Americans really need to take a hard look at the values they are showing versus the values as described in the Declaration of Independance and the US Constitution. Gays are being deprived of rights that our own founding charters say are "inherent" to them by God.
Yet it is those who say they speak for God that drive the opposition and continue the divisiveness and prejudice.
The elephant in the room when it comes to the USA is that, despite supposedly being the "most free", we are the most sexually repressed and puritanical nation in western civilization.
I think we'll get to the point where homosexuality is just as accepted socially and legally as heterosexuality, but I think it will unfortunately be a long road.
I have many reasons to be proud to be an American, but on this issue I feel a bit of shame for my country...as should we all.
- October 12, 2010 at 3:55 PM


text:
Clue: Table of contents, e.g.
We have 1 answer for the clue Table of contents, e.g.. See the results below.
Possible Answers:
Related Clues:
- Bibliography, basically
- Tabularize
- Santa checks it twice
- Aid for Santa
- It's just one thing after another
- Wish ___
- "Schindler's ___"
- Tick off
- Letter-to-Santa enclosure
- Top 10, e.g.
Last Seen In:
- New York Times - September 29, 1997
Found an answer for the clue Table of contents, e.g. that we don't have? Then please submit it to us so we can make the clue database even better!