(3) . Much of the work relating mechanical states of cells and their biosynthetic response is based on isolated cells, or cells embedded in explant samples removed from their natural in situ environment. Neither the mechanics nor the associated biological responses of chondrocytes have been studied in intact cartilage attached to its native bone or in the intact joint. The purpose of this study was to design and apply methods to study the mechanics of chondrocytes in the intact knee in live animals while loaded physiologically through muscular contraction. METHODS In order to achieve the purpose of this study, we developed a novel in vivo testing system that allows for quantification of the mechano-biology of chondrocytes in the intact knee of live mice (Figure 1). Mice are fixed in a custom-built jig on the stage of a dual photon microscope. Controlled forces of the knee extensor muscles is produced through direct muscle stimulation.. Imaging of the chondrocytes is performed using a Zeiss 40× 0.95 NA water-immersion objective coupled with a Coherent Chameleon IR laser tuned at 780 nm for two-photon excitation.


Post-war suburban communities were designed for efficient vehicle travel with little consideration for walking and bicycling. Developing master plans for these communities requires a context-sensitive approach, a large toolbox, and broad outreach strategies. Jennifer Donlon Wyant will talk about recent master plan developments in California communities and the lessons learned.


Based on an increasing body of evidence, it is generally accepted that culturing cells in three dimensional (3D) models can lead to superior cell viability, differentiation and function compared to existing conventional culture systems where cells largely grow as monolayers on two dimensional (2D) substrates. These enhanced qualities are important for the retention of the in vivo-like cell phenotype and cell differentiation potential and subsequent functionality as required for downstream applications. Here we demonstrate the application of Alvetex®Scaffold technology for the growth and differentiation of mesenchymal cells and the formation of differentiated tissues.


Acute Phase Proteins are blood proteins primarily synthesized by hepatocytes as part of the acute phase response (APR). APR to disease is accompanied by an increase in the circulating concentration of a number of plasma proteins which are collectively known as the Acute Phase Proteins. According to the concentration, APPs are classified in positive APP, if they increase or negative APP, if they decrease. During mastitis, APPs move from the systemic circulation to mammary gland or there could be de-novo synthesis of the APP within mammary gland tissues. Among the APPs, Serum Amyloid A (SAA), Haptoglobin (Hp), Alpha 1-acid glycoprotein and Lipopolysaccharide binding protein play a major role during mastitis in cattle and their concentration will increase with the severity of the infection, inflammation or trauma. SAA is involved in defense against Gram positive and Gram negative pathogens. SAA acts by modulating innate immune system and by acting as an opsonin. Among the SAA isoforms, mammary associated SAA3 (m-SAA3) is important. The blood concentration of SAA and Hp increases dramatically after LPS infusion, with SAA (acute and middle phase of APR) appearing before Hp (Late phase of APR). The herd level APP might be useful for determining the prevalence of clinical and subclinical infections indicated by the high serum concentration of selected APP and by serving as the prognostic tool. APPs, used as markers of animal health may possibly be influenced by environmental factors, handling procedures and other types of stress in the absence of disease.


Semantic links within text play an important role in understanding text. Cause-effect link is one of the basic semantic links that represents logic order between representation components of text. The importance of cause-effect link has been recognized and investigated in linguistics, but it has not been accurately measured to support computing applications. This paper is to investigate the role of cause-effect link within scientific paper. Research is conducted along two paths: (1) Human observations: Professionals find cause-effect links within a set of given papers, and then observe the number, the distribution and the keywords coverage of cause-effect links within each paper. The statistical results show that cause-effect links cover 76% keywords within paper on average. (2) Automatically discover more cause-effect links within a set of papers by developing a pattern-based algorithm. The automatically discovered cause-effect links validate the properties drawn from human observations. Experiments show that the algorithm can extract more than 80% of manually labeled links, and the automatically extracted links contain 75% of keywords within paper on average.


The role of strike‐slip faults, such as the Ailao Shan shear zone in southwestern China, in accommodating the India‐Eurasia collision remains controversial. Cenozoic sedimentary rocks preserved along the northeast side of the Ailao Shan shear zone, however, record the nature and timing of exhumation of shear zone rocks. Field mapping shows that the lower strata consist of early Oligocene lacustrine red mudstone and gypsum and the upper of late Oligocene to Miocene fluvial conglomerate with rare, fine‐grained, fossil leaf‐bearing intervals. Sediment derived from shear zone gneiss is present only in the upper part of the section. Our observations indicate deformation began in Oligocene time, with the onset of rapid exhumation by early Miocene time, consistent with existing geochronologic results. Exhumation must have ended before the formation of a regional low‐relief erosion surface and the onset of brittle deformation along the Red River fault, probably in early Pliocene time. Rapid exhumation of the Ailao Shan shear zone has been interpreted to have occurred in transtension, accommodated by a normal fault on the northeast margin of the shear zone. However, we observe consistent and pervasive shortening structures within the Cenozoic strata, including overthrusting and folding of the basin along faults defined by thick gouge zones within weak Cenozoic lithologies. Deformation is likely syndepositional. These structures are distinct from subvertical deformational features associated with the active Red River fault. Our field data thus support mid‐Cenozoic transpressional exhumation of the Ailao Shan shear zone. This is consistent with regional evidence for widespread left‐lateral and compressional deformation in the region to the east of the eastern Himalayan syntaxis during this time. Focused erosion along the Red River, established by late Oligocene time, may have contributed to deeper exhumation of the northeast part of the shear zone.


Objective To investigate the relationship between the serum CA199,CA724,CA242 and gastric carcinoma(GC).Methods Levels of serum CA199,CA724 and CA242 were detected by radioimmunoassay in 63 cases of GC,30 cases of chronic atrophic gastritis dysphasia(CAGD),and 30 age-matched healthy controls.The relationship of variation of serum CA199,CA724 and CA242 with malignancy degree,liver metastasis and TNM stages of GC were analyzed.Results Serum levels of CA199,CA724 and CA242 in GC group were obviously higher than those in CAGD group and healthy controls(P0.01) respectively.There were significantly correlations among CA199,CA724,CA242,malignancy degree,liver metastasis and TNM stages(P0.05).Combined detection of CA199,CA724 and CA242 could improve the sensitivity and accuracy of GC.Conclusions The elevation of serum CA199,CA724 and CA242 in patients with gastric cancer is the most important factors for occurrence and development of GC.Detection of the variation of serum CA199,CA724 and CA242 may have clinical significance for the diagnosis.


The present dissertation contributes to studies of phraseology in learner English. It is an analysis of recurrent sequences of words in a corpus of learner Computer-mediated Communication. English, collected by means of asynchronous chats in an Italian university context. Previous research has argued that the use of recurrent word sequences plays a major role in learner English fluency both in writing and in speech, and is one of the factors behind learner English register failures. Using a corpus-driven approach, the study analyses the most frequent word sequences extracted from the specially compiled Learner Chat Corpus (LCC). To determine the level of adaptation of learner English to different registers, data regarding 3-word sequences from LCC is compared with the Italian subcomponents of a well-known corpus of learner writing (ICLE, Granger et al. 2002) and a corpus of learner speech (LINDSEI, Gilquin et al. 2010 ). The cross-corpus comparisons provide evidence that learners employ combinations which make their English suitable to the mode they are using for communication. Quantitative and qualitative findings from the present research support only in part previous studies of learner English in terms of recurrent sequences. This is probably due both to the informality and spoken-like quality of CMC, and to its motivational advantages and processing differences connected to the fact that learners can monitor their output while communicating because learner language production is distanced by the electronic means.


The invention discloses television signal receiving equipment and a software upgrading method with a voice prompt function. The software upgrading method adopts the design scheme that a system automatically calls a voice prompt audio file and the voice prompt audio file plays in a loop till a software upgrading process is finished. According to the software upgrading method, the audio file is automatically called in the software upgrading process, and a software upgrading prompt voice is played, so that the upgrading failure probability due to artificial misoperations can be reduced in the system upgrading process for users; a prompt effect is extremely significant special for the elderly and illiterate people; and compared with the traditional literal prompt method, the success rate of system upgrading is increased greatly.


In order to develop the density functional approach for calculating the diagonal elements of the second-order reduced density matrix, we present the restrictive conditions on the kinetic energy functional. These conditions are useful for devising the approximate form of the kinetic energy functional, which is a key issue for this approach.


MERV stands for Minimum Efficiency Reporting Value. It is a rating system incorporated into the test specification of ASHRAE 52.2. It assigns a single number to a filter in an effort to identify its minimum performance in removing particulate from an airstream. Higher numbers are intended to indicate higher filtration efficiency, but many industrial dust collection industry experts would argue that they don't.


The U.S. has signed an agreement with the Russian Federation for the purchase of 500 metric tons of highly-enriched uranium (HEU) taken from dismantled nuclear weapons. The HEU will be blended down to low-enriched uranium and will be transported to the U.S. to be used by fuel fabricators to make fuel for commercial nuclear power plants. Both the U.S. and Russia have been preparing to institute transparency measures to provide assurance that nonproliferation and arms control objectives specified in the agreement are met. This paper provides background information on the original agreement and on subsequent negotiations with the Russians, as well as discussion of technical aspects of developing transparency measures suited to the facilities and processes which are expected to be involved. Transparency has been defined as those agreed-upon measures which build confidence that arms control and non-proliferation objectives shared by the parties are met. Transparency is a departure from exhaustive, detailed arms control verification regimes of past agreements, which were based on a presumption of detecting transgressions as opposed to confirming compliance.


As the new tendency of interaction design,service design should obey human-centered design principle,designers could compile service list,service blueprint,process map and make sure the service string and service prototypes are appropriate for a set of discrete moments through environment description,company branding analysis,etc.Thus designers can build the center of digital services,applying these techniques can lead to an excellent service design.


The Nuclear Center of VALDUC (ate d'Or) operates two reactors for hardening studies of electronics. The PROSPERO and CAUBAN reactors are fast fission neutron sources, the former in a steady-state mode, the latter in a pulsed mode. These two critical assemMies use solid uranium 235. The operating characteristics of the reactors and fluence data are given. Recent neutron spectrum determination around PROSPERO allows us to specify on different locations the neutron fluences (I-MeV equ'hlent for silicon) from measurements performed on activation detectors.


Norwegian journalist Kristin Granbo joins Polis in October for a month to research the topic of how the way we report news for children is changing. For more information on this research project please contact firstname.lastname@example.com or contact Kristin via @KGranbo "Will you whip this story out on our website?" The question came from my editor. Some news event had just occurred, and we saw the story plastered on every news site at home and abroad. I wasn't sure if he'd heard his own words, but I was very surprised at the wording. We'd never "whipped" out any news story in our newsroom. A newsroom which should be home to well formulated, thoroughly explained stories that inform, but still dampen fear. We write news for children.


To provide an effective and accurate forecasting model and decision support for shipping market participants,taking Baltic Dry Index(BDI) as research object,the statistical tests on stationariness and nonlinearity of the BDI time series data were analyzed,and mathematical statistic method and neural network technique were used to set up an effective fuzzy neural network model.Comparing with the traditional neural network,the fuzzy neural network has better performance for prediction capability.


In order to cultivate high-quality academic or applied talents, the aspects of college English curriculum need to change from English for General Purposes to ESP (English for Specific Purposes). English teaching should focus on academic purposes and special needs. Therefore, the biggest challenge of college English reform is the smooth realization of college English teaching from EGP to ESP transition. In this paper, the constraints in this transition process will be analyzed to focus on coping strategies.


. During the last decades, a series of cutting-edge Information and Communication Technologies (ICTs) gained momentum in industry and academia. Including several technologies such as the Internet of Things, Clouds, and Smart Sensors, to name a few. As a digital paradigm that fosters decentralized planning and control along with mass personalization in manufacturing, Industry 4.0 is currently paving the road to a fourth industrial revolution. In this paper, we depict important challenges in this context of ICTs and mass personalization of Industry 4.0, ambitioning the achievement of conflicting production goals of price and customization. In our holistic vision, we discuss these challenges under both the prisms of computer science and production engineering. Resumo


Diessel's The Acquisition of Complex Sentences examines the development of complex sentences in early child speech, based on vast observational data. The data consist of about 12,000 multiple clauses produced by five English-speaking children between the ages of 1;8 and 5;1, obtained from the CHILDES database (MacWhinney (1995)). This is probably the first study which has examined such a large amount of data in the acquisition of complex sentence constructions in English. In this sense, Diessel's detailed and thorough investigation contributes greatly to the study of the development of complex sentences. However, Diessel's analysis based on construction grammar and the usage-based model does not seem to be sufficient to undermine the innateness hypothesis proposed in the theory of generative grammar (Chomsky (1965, 1981, 1986, 1995, 2000, 2001, 2004)). In this review, some experimental studies based on the innateness hypothesis are introduced and compared with Diessel's analyses of the acquisition of corn-


The interaction of sound waves with vortices in type-II superconductors is a field of active study: The attenuation of transverse sound waves through a vortex lattice has been analyzed experimentally in Ref. 1; the generation of ultrasonic waves in the mixed state was observed experimentally; 2 sound attenuation by helicon-vortex modes was considered in Ref. 3; sound-vortex interaction and the acoustic Faraday effect has been studied in Ref. 4; the generation of sound waves by moving vortices was considered theoretically. 5 Since vortex motion is driven by an electric current, any peculiarity of the vortex radiation friction due to emission of acoustic waves influences the current-voltage characteristic, and will imprint a nonlinear feature on the I-V


Early fire detection is quite important to fighting of forest fire. A lightweight YOLO forest fire detection model is proposed in this study. First, the YOLOv4 object detection model is selected as the overall framework for fire detection. In order to reduce the number of parameters and computation, this study replaced YOLOv4's backbone network with the lightweight MobileNetV3. Finally, the data set with flame and smoke is used for training model, and fire-like images are used as negative samples to improve the robustness of the model. The experimental results demonstrate that compared with YOLOv4, the number of parameters of the proposed architecture is reduced by 62.78%, and inference speed increases by 3.04 times,. Moreover, the detection accuracy of the proposed algorithm achieves 0.666 mAP. The proposed method has advantages of less number of parameters, fast inference speed and low memory occupation. The method presented in this paper has referential value to realize real-time forest fire detection and object detection on embedded devices.


Our objective to investigate the ranges of Reticulated Platelets in Lanzhou Region and to explore the cause of variations of Reticulated Platelets in patients inflicted with chronic liver diseases.The flow cytometry was used to determine the percentage of Reticulated Platelets.The normal percentage for adults in Lanzhou was 2.59%(0.37%~9.28%).Hence the range of Reticulated Platelets in Lanzhou was set up essentially.The lower level of platelets in patients with chronic liver diseases was due to peripheral destruction.


In his 'After the Archive' article, Brockmeier outlines limitations of the 'archival model' of memory, taking into account several dimensions of the burgeoning field of memory studies. In responding to the weaknesses he cites, he introduces ideas about narrative and its role in shaping human thought and memory. While narrative brings important assets to Brockmeier's effort, it also carries conceptual baggage that is examined here. In particular, the prospects and problems of what philosophers have labeled 'narrative memory' are outlined, and narrative tools are presented as having both empowering affordances as well as limiting constraints.


A method of measuring mechanical impedance at discrete frequencies is outlined; this method follows directly from Fay's telephone receiver analysis. The application of this method to the measurement of the mechanical transfer impedance at a violin bridge is discussed and some experimental results presented. Preliminary results of some other tests on violins are also discussed.


Our profession needs to face head on the issues raised in the report of the Shipman inquiry. The main charges against the profession are structural and cultural. The structural and systematic loopholes that allowed Shipman, Ledward, and others to go undetected for years are being addressed by the chief medical officer's review of the General Medical Council and its proposals for revalidation of doctors. What about the "medical culture" that allowed these events to occur? What about the charge of collusion, the charge of a doctors' "club" looking after doctors? What about the culture that frowns on a doctor who questions colleagues or superiors about their practice? How do we change the culture of a profession? I think large parts of our profession are still in a state of denial.

We get frustrated when some doctors talk as though nothing needs to change much

I worked in the same area as Harold Shipman. The doctors in Hyde and Tameside were also in denial to begin with. After the initial shock and disbelief we thought Shipman was a one off, an aberration, an evil murderer, and nothing to do with us. The implication of this denial was that we thought we did not need to change anything.

It was only when we were brought face to face with Shipman's actions that our feelings, and then our behaviour, began to change. All doctors in the Hyde area had countersigned some cremation forms brought by Shipman. When we were interrogated by lawyers representing the relatives at the inquiry and forced to analyse these cremations, some were natural deaths and others were found to be murders. All of us have felt the pain of bereaved relatives, many of whom are our patients, and some relatives are still grieving.

Everyone in Hyde knows somebody in his or her circle of family and friends who was affected by the Shipman tragedy. One of Shipman's victims was the wife of a patient I looked after for 15 years. They were a lovely, decent couple who had worked hard through their lives and asked for little in return. They moved, joining Shipman's list, and he murdered her. Another victim was the wife of a friend of mine. Both husband and wife were Shipman's patients and spoke highly of him. My friend died a natural death, but his widow was later killed by Shipman. How dare he? How could he? And he was "one of us"!

Gradually but inevitably the denial turned into anger, and, much later, the anger into acceptance; but the experience changed our outlook and our culture and drove us to action. The Tameside Local Medical Committee protocol for filling in cremation forms was devised. We now routinely inform relatives of dying patients that if a cremation is required a second doctor will want to phone or meet them to ask questions. We name the carers and relatives involved, including their contact details. When countersigning another doctor's form we routinely ask carers and family of the deceased if they have any concerns.

Our primary care trust, having itself undergone scrutiny and self analysis, now has a robust policy on controlled drugs and a high level performance management group. The trust has drawn up a policy on whistleblowing, which it has recommended all practices to adopt. It allows doctors and other staff to voice concerns regarding a fellow professional's performance or conduct that may be compromising the safety of patients. This does not mean we have lost trust in our colleagues—merely that we are more vigilant, making patients' safety our first concern.

Most doctors provide good care most of the time, but this is not acknowledged or celebrated in a public way. It is not surprising that doctors would feel they are being "criminalised" for the sake of a few high profile cases of rogue doctors. Moreover, we get frustrated when some doctors talk as though nothing needs to change much. Doctors who speak in favour of the Shipman report are often castigated; some dare speak only in private. This is an unhealthy state of affairs. The profession should have an open culture. The response from many of our leaders, with notable exceptions, has been a defensive one. Perhaps they need to feel the pain before they change their attitude. They will be most welcome to visit Hyde and share our pain and the grief of our patients. However, please let us move on from denial towards, yes, anger, and then acceptance and action.


Current inductive logic programming engines are not practical in the sense that they are hard to use and understand by the naive end-user. Various guidelines are presented for developing practical inductive logic programming engines that should be widely applicable and easy to use by the typical end-user of data mining systems. The presented guidelines summarize the author's personal experiences and opinions gathered during the design and development of various inductive logic programming systems. In forming these opinions, the author was strongly in uenced by discussions within the consortium of the ESPRIT project Aladin, though the guidelines do not necessarily re ect any kind of project consensus.


Turkey's president paid tribute to Bosnia and Herzegovina's founding leader at his final resting place.Recep Tayyip Erdogan visited the gravesite of Alija Izetbegovic, the nation's first president, at the Kovaci War Memorial and Cemetery.


Field horsetail was grown from rhizome segments for 28 and 52 d under 35, 60, 120, 170, and 320 μmol m–2 s–1 photosynthetic photon flux (PPF) and four continuous nitrogen (N) supply rates corresponding to a total of 1 to 6 kg N ha–1 28 d after planting (DAP) and 6 to 41 kg N ha–1 52 DAP. There was no response to the supply of N in the first growth period, probably due to the mobilization of nitrogen available in the planted rhizomes, and only dry weight (DW) of new belowground production, mostly roots, responded to increased light. Rhizomes were produced during the latter part of the 52-d period. Requirements for light and N during the 52-d period were low, because total new tissue production was only reduced at the lowest levels of light (35 μmol m–2 s–1 PPF) and the two lowest N supply rates (6 and 18 kg N ha–1). The ratio of shoot DW to belowground organ DW increased only as the N supply increased. Shoot height response to an increased N supply was also small. Field horsetail can therefore be considered tolerant of low levels of N but will be overtopped by fast-growing species when competing for increased supplies of N. Both an increase in N supply and a reduction in light increased the reduction of DW of the planted rhizomes, whereas tuber production was favored by low N supply and high light intensities. Field horsetail can tolerate low levels of N but is not likely to be competitive in a dense crop stand.


Various super-resolution methods can correctly estimate the missing high frequency components of enlarged images. However, they mostly require high computational costs, which is not suitable for real-time processing. For a super-resolution with low computational costs, the proposed method is simply realized via the block matching technique with a small search area. Since it utilizes the image self similarity and sparsity, it produces visually efficient interpolated images. In the simulation, it is shown that the proposed method greatly outperforms the bicubic in a visual quality of enlarged images, objectively and perceptually.


Childhood Functional Gastrointestinal Disorder (FGID) knowledge is important for healthcare workers (HCWs), particularly in isolated islands, such as Mandangin island, Sampang, Indonesia. Video conferencing technology has been globally used as medical education media to educate among HCWs. This study examined the effectiveness of video conferencing technology about Childhood FGID in limited resources HCWs. This cross-sectional study was conducted among 20 HCWs from Mandangin's community health center along with community medicine by the Department of Child Health, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital. The subject was assessed for general characteristics and FGID pre-test to examine HCWs' knowledge before the seminar through video conferencing. FGID pre-test was consisted of seven questions and randomized for FGID post-test after the seminar and the question-answer part was done. The pre-and post-test was compared using the Wilcoxon rank sum test using SPSS version 20.0. Among 20 subjects, 80% were female, and 45% had the last education of Diploma Degree (D-3). There was a significant difference between pre-and post-test among subjects (p<0,05), of which 16 (80%) subjects had an increase in post-test compared to the pre-test result. Health education using videoconferencing technology effectively increased knowledge about childhood FGID in limited resources healthcare workers and expected to be a sustainable program in the community health center.


The purpose of this paper is to explore the footwear industry's supply chain management, by considering the retail outlets and how they can best source their products. Particular emphasis is given on the production side as it is particularly complex, labour intensive and has long processes which constitute this supply chain fundamentally different from other retail supply chains. An understanding of the entire supply chain, from raw materials to consumer, is required in order to properly assess retailer supply chain management. At the moment, trade shows provide a market overview and a platform to place orders. Furthermore, agents, representatives and distributors arrange for private exhibitions or visit clients themselves. All current methods have at least 6-months between collecting orders and delivering finished products. The author carried out research by incorporating semi-structured interviews on-site the MODA UK exhibition with advanced literature review. The findings suggest that footwear supply chains defy "normal" supply chain features of reducing lead-times and moving pressure from supplier to retailer, especially when looking at small to medium retailers. A gap in current academic literature was discovered, making this research a novel piece of work and exploratory in nature. Further research is required in order to test for hypotheses, such as particular improvements in the supply chain and their effect.


An experimental entrained flow coal gasification furnace with a circular section was customized according to the conditions for flameless combustion of pulverized coal and three tiers of PC nozzle,and three tiers of air nozzle are arranged in the furnace opposedly and tangentially respectively.Cold air flow tests in the furnace and PC gasification tests based on the flameless combustion under different typical conditions were carried out and the experimental results show that PC gasification is optimum when the three tiers of PC nozzle are simultaneously in operation and the atom ratio of O2/C is about 1.0 and meanwhile,the concentration of CO+H2,the calorific value of the synthesized gas and the efficiency of the cold coal gas are all at their maximum value,i.e.30.3%,4477kJ/Nm3 and 75.29% respectively.


The reaction of electronically excited iodine monochloride with cis- and frans-l,2-dibromoethylene has been studied in detail. Selective excitation of 137C1, using a CW dye laser, gave cis- and trans-I-bromo-2-chloroethylene products contain- ing up to 78.4 and 73.9% 37Cl, respectively. The quantum yield of the two products together was about 30%. The product ste- reochemistry for the reaction of ICI* with I ,2-dibromoethylene is similar to that of free CI atoms, but differs from that of the


Thermosetting materials are expanding their market penetration owing to their excellent heat resistance and performance characteristics. Energy conservation considerations have also resulted in the development of processing techniques involving the simultaneous polymerization and shaping of the part. The processability of a reactive system is dependent on the thermal and deformation history which is experienced by the material. Despite this processing sensitivity, significant new developments have occurred in recent years including improvements in machinery design, process automation and control, novel processing technology such as RIM and pultrusion, and advances in material formulations. The processing of reactive systems will be considered with emphasis given to the recent developments concerning mathematical analysis and simulation of the process dynamics and the relationship between processing history and part properties.


The invention relates to an ironing appliance, comprising a base (1) generating steam and an iron (3). The base and the iron are connected by cables. The base comprises a water tank (12) and an accommodation cavity (15) for containing cables. The ironing appliance is characterized in that the accommodation cavity is extended transversely relative to the base (1) and comprises at least one opening (15A, 15B) of a channel leading to the one side of the base (1). The accommodation cavity (15) comprises at least a wall (16) made of a translucent or transparent material in order to observe the water level within the water tank (12).


IntroductionThe Great Recession that started in 2008 has had significant effects on the US and global economy; estimates of the amount of US wealth lost are approximately $14 trillion (Luhby 2009). Various causes of the financial crisis have been cited, including lax regulation over mortgage lending, a growing housing bubble, the rise of derivatives instruments such as collateralized debt obligations, and questionable banking practices. In addition to these and many other reasons, we explain two factors that partially contributed to the crisis: certain management incentives and fair value accounting standards. Following the dot-com bubble in 2000 and the September 11, 2001 attacks, the U S. economic policies of low interest rates coupled with easy credit, lower taxes, and the cheap dollar generated significant economic growth from 2000 to 2007. Low interest rates motivated many in the United States to pursue home ownership, a goal long propagated and encouraged by the government as a wise investment and worthy social objective. Easy credit facilitated by agencies such as Fannie Mae and Freddie Mac enabled financial institutions to focus on the lucrative subprime mortgage market. Mortgage lenders initiated a growing number of new home loans, many of which were granted to individuals with a poor credit rating, who would eventually be unable to service monthly mortgage payments once interest rates increased. Unfortunately, gains generated from securitization of the home loans and from income on the servicing of the loans inflated financial profits, motivating executives of mortgage origination firms to focus on quantity, rather than quality, of borrowers. Investors, seeking new investment opportunities, fueled the demand for mortgage backed securities that were created through securitization of the home loans. Such securities received high ratings from analysts who also did not correctly assess the underlying default risk.The current economic and financial crisis has significant implications for accounting, both for practice and for the research community. In the areas of financial accounting, auditing, management accounting and the regulatory institutions that oversee accounting and auditing practices there are genuine worries that the crisis has revealed numerous problems and inadequacies. In the academic and research community it certainly has illuminated issues that are in need of serious research attention. More than that, however, the crisis also points to the rather limited focus of much current accounting research. Too much intellectual inquiry in the area of accounting seems to operate within the parameters set by practice rather than questioning and challenging these, at least from time to time. Although the implications for research in accounting may not be so great as that within the finance research community where the serious lack of critical research is much more visible, a more detailed consideration of the implications of the crisis for accounting research nevertheless points to the need for a more rigorous investment in diverse research perspectives rather than an unquestioned following of a singular mainstream view. In early 2005, interest rates began to rise, increasing up to 8.25% in 2007 from 4% in 2004. In response, a large number of homeowners, particularly those with adjustable rate mortgages, began to default on their monthly payments. In 2007, New Century Financial, the second largest subprime mortgage originator in the US, announced a restatement of its financial statements for the first three quarters of 2006 due to under-reserving certain loan loss provisions. This announcement was followed shortly thereafter by large losses for firms with significant subprime positions, including Bear Stearns, Lehman Brothers, Merrill Lynch, and Citigroup. The market (using the Dow Jones Industrial as a benchmark) dropped precipitously from over 14,000 points in October 2007 to under 7,000 in March 2009, with a drop of almost 2,000 points in one week alone in September 2008. …


A major drawback of block discrete cosine transform-based compressed image is the appearance of visible discontinuities along block boundaries in low bitrate coding, which are commonly referred as blocking artifacts. Another fundamental problem in the field of image processing is image denoising. There are several ways through which noise can be introduced into an image, depending on how the image is created. In this paper, a post-processing method based on three separate filtering modes is proposed for removing these discontinuities. Then a median filter is applied to remove the noise from the image. Then evaluate the performance of the proposed method using performance metricPeak Signal-to-Noise Ratio. Experiments shows that the proposed method gives better performance in terms of PSNR and excellent results compared with other approaches. Key Words-Blocking effect, Denoising, Deblocking


The reaction of 2-(trifluoroacetyl)pyrrole with trans-3-bromo-3,4-dihydro-4-hydroxy-2,2-dimethyl-2H-chromene-6-carbonitrile under basic conditions has been shown to afford high yields of (4R*, 5aS*,11 bS*)-5a-hydroxy-6,6-dimethyl-4-trifluoromethyl-5a,11 b-dihydro-4H,6H-pyrrolo[1′,2′:4,5]-oxazino[2,3-c]chromene-10-carbonitrile rather than the anticipated amino alcohol. The unequivocal structural assignment of this unusual tetracyclic product by spectroscopic and X-ray crystallographic techniques is described and possible mechanistic explanations for its formation are discussed. Analogous reactions of pyrroles substituted in the 2-position by formyl, acetyl and benzoyl moieties have been shown to behave in an essentially similar manner, suggesting that the reaction is general for 2-acylpyrroles.


In this paper, we present a novel computational model that uses ground tracks adjacent to the interconnect line for alleviation of signal overshoots. It is found that the adjacent ground tracks increase the capacitance of the interconnect line and therefore the damping factor, which reduces the signal overshoots and undershoots to acceptable levels. The proposed model is based on the unified approach (variational analysis combined with transverse transmission line technique) and uses existing ground tracks that are commonly used for crosstalk mitigation between coupled interconnects, thus avoiding any physical changes in the interconnect geometry. Results are verified using finite-difference time-domain simulations and measurements performed on a vector network analyzer. The novelty of our model lies in the easy and efficient computation of line parameters and damping factor. The proposed model can be used for mitigation of signal overshoots in high-speed interconnects, whether on-chip, or at packaging, board, or system levels, where overshoots are a common design headache.


Master's programmes in arts and cultural management require a wide range of skills (solid academic results in multiple disciplines, personal experience and involvement in the arts field, linguistic skills, personal and relational abilities) but they prepare students for an uncertain future in terms of employment and remuneration. Nevertheless they enjoy great success among French students. This apparent paradox has led me to investigate the social genesis of vocations for cultural management. My analysis of this genesis is based on a survey on applicants to these programmes, which sheds light on their sociological profiles and their motivations. I show that this career aspiration may stem from ethical motives, strategies against social downgrading or conversions of artistic vocations.


Pinguicula calderoniae is described as a new species to science. It grows on calcareous rocks in the cloud forest in the border of Queretaro and San Luis Potosi states. On account of its bilabiate corolla with long-infundibuliform tube, as long as or shorter than the spur, it is placed in subgenus Pinguicula, section Longitubus. This new taxon is clearly differentiated from other members of this group by its long lanceolatelinear summer leaves, which are unique in the section.


Two-patients with spontaneous rupture of the tendon of the extensor pollicis longus, after the fracture of the lower end of radius are reported.They are operated by mean of the tendon transfer of the extensor indicis, and are obtained the good results.The etiology and the pathology of the conditions are refered.


Background: Catfish is a freshwater and saltwater fish type with a wide distribution throughout the Indonesian archipelago. This study was conducted to analyze Indonesian catfish's genetic diversity and evolutionary relationships based on the mitochondrial ND6 gene.
Methods: Twenty-eight catfish samples were collected from nine rivers and one ocean in seven provinces of Indonesia. The MT-ND6 gene was amplified by using a set of primers (BaungND6F and BaungND6R). The MEGA X software was used to examine the MT-ND6 sequences for genetic variation and phylogenetic relation between Indonesian catfish populations. Result: There were 167 nucleotide site variations and thirty-two amino acid variations in the MT-ND6 gene. The genetic difference among populations ranges from 0.9 to 25% and the average evolutionary divergence in the overall populations was 14%, with catfish BB and PM having the closest genetic distance, while the farthest is BF to MP and BF to MS. In conclusion, the phylogenetic tree indicated that there were four distinct catfish clades in this study: MP, MS, KR, PM, BB and KS had been grouped with Hemibagrus nemurus (Bagridae family), EM had been grouped with Mystus vittatus (Bagridae family), BSBJ had been grouped with Pangasius pangasius (Pangasiidae family) and PD and BF had been grouped with Netuma thalassina (Ariidae family).


1. Any figure in a measurement, including zero, is a significant figure if it contributes to the accuracy with which that measurement is expressed. But a zero which is only a "place holder^' is not a significant figure. In the example above, 29.4 kg has three significant figures whether we express it in that way or as 29,400 g or as 29,400,000 mg; and 71 mg, 0.071 g, and 0.000071 kg have two significant figures each. But 29.40 cm has four significant figures even though 29.4 cm has only three, for the zero shows that the value has been measured to the nearest hundredth of a centimeter.1 2. The concept of significant digits is an important consideration in connection with both precision and accuracy. The digits of an approximate number are significant if they serve a purpose other than merely helping to place the decimal point. All nonzero digits are significant. A zero may be significant or nonsignificant. A nonsignificant one is not therefore insignificant, unimportant, or useless. It serves solely as a place holder. Zeros situated between significant digits are always significant. In the number 506.3 the zero is a place holder; it gives the 5 its correct position relative to the decimal point. But it does more; it tells us how many groups of ten are present—there are none. On the other hand, if 5000 is an approximate number precise to the nearest thousand none of the zeros are significant. Their only function is to give the 5 its correct position, or—what amounts to the same thing—they place the decimal point. There is no reason for writing fifteen, correct to the nearest unit, as 15.0. If 15.0 is correctly used the zero is used to specify that to the nearest tenth, we have no tenths. If we know nothing, or wish to say nothing, about the number of hundredths of a unit in the measurement we should not write 15.00. Terminating zeros in a fraction are used solely to specify that we know there are no units of that particular size. They do not help place the decimal; that has already been done. But they serve a role other than that and therefore are significant. On the other hand, initial zeros in a fraction are never significant. In the number .05 the zero merely places the decimal. But is it not true that it tells us we have no tenths? It is true that we have no tenths but we do not need the zero to tell us. The fact that the 5 is the first nonzero digit tells us that it stands in the position corresponding to the largest unit in the measurement. We do not write 56 as 056. There are no hundreds present but we do not need the zero to tell us. All the digits of a mixed number are significant. Consider 5000.0. The final zero specifies there are no tenths of a unit. If we know how many tenths of a unit are present we must of necessity know how many units, tens, and hundreds are present. The zeros in the integral part are between significant digits and are thus significant.2


To satisfy current reconnaissance trends, high resolution, small format cameras are becoming more necessary.. The KS-121A Camera System is representative of this trend. Developed to improve the reconnaissance capabilities of the RF-5 aircraft, the KS-121A 70-mm Frame Camera. System offers high resolution in a small format. The small size permits the mounting of four cameras in the aircraft nose which may be configured to suit a variety of missions. The camera features interchangeable lenses of three focal lengths, a wide range of shutter speeds, automatic control, of both shutter speed and lens relative aperture, vacuum film flattening, and built-in-test.


In this paper, a Fuzzy Inference System(FIS) based watermarking algorithm in Discrete Wavelet Transform(DWT) domain is proposed. A 2D fuzzy inference values, in which the inputs are parameters of the coefficients of the DWT block of the original image and the output is strength of watermark embedded, is devised. The fuzzy inference algorithm guarantees that the watermark to be embedded into the original image adaptively. The experimental results shows that proposed approach is robust to the digital image processing schemes.


The aroma of fermented fish sauce comprises three distinct notes, cheesy, meaty and ammoniacal. Analysis showed that the cheesy odour was produced by lower fatty acids and the ammoniacal odour by ammonia and amines. The meatyaroma was much more complicated and was not analysed, but it was shown that it could be produced by atmospheric oxidation of precursors that were still present in mature sauces. Individual fatty acids were determined in sauces at various stages of fermentation and an hypothesis explaining the origin of the acids is deduced from the results.


The article presents experimental data, based on which the influence of various factors on the strength and thermophysical characteristics of porous heat-insulating materials was studied.
Porous bodies in thermal power engineering are used for thermal protection of power plants, various aggregates, in thermal insulation structures of buildings and technological networks. The properties of these materials and the field of use depend on their chemical composition and method of production.
The task of this research is to obtain a raw material mixture for heat-insulating material of the closed-cell type with increased thermal resistance and porosity by optimizing its qualitative and quantitative composition. The goal is also to improve the method of obtaining porous heat-insulating material by changing the temperature and time regimes in order to improve the physical, mechanical and operational characteristics, which will allow the material to be used in a wider temperature range.
Based on the dependences of strength and thermophysical properties on the density of the finished material obtained in the work, it was concluded that the best characteristics are the samples of the porous material with the lowest density, which are formed at the maximum humidity of the raw material. Kinetics of drying and heat treatment of the raw material mixture, thermal regimes are the main factors that determine the porosity, strength and thermal conductivity of the finished heat-insulating material.
Performed laboratory studies of the material proposed in the paper allow choosing the required temperature regimes of heat treatment. Thus, the task of further research is to choose a method of organizing effective heat and mass exchange, modeling these processes, experimental testing of the obtained data, and creating a method for determining the main technological and structural parameters of the method of obtaining a new material.
The performed experimental studies made it possible to determine the conditions for the implementation of new technologies for the production of porous materials with the possibility of predictive determination of their properties.


The experiments of cyclic loading and unloading,uniaxial and triaxial stiffness of rock and the numerical modeling analysis of deep rock mass are completed in Linglong gold mine.Based on the results the experiments and numerical modeling,the phenomena of higher elastic strain energy and the distribution of rather large elastic energy resilience in deep rock mass are analyzed in general.The releasing of the elastic energy resilience has high impact characteristic.The great possibility of rock burst during deep mining excavation in Linglong gold mine are concluded by using various prediction criteria of rock burst.The conclusion is that the rock burst can be forecasted.The methods and the safety precautions against rock burst are also proposed according to the actual construction.


The objective of this study is to evaluate the behavior and seismic performance of tube structures with buckling-restrained braces by the nonlinear static procedures. For this purpose each tube structure which various characteristics are used. And this values used comparative analyze for seismic performance and alleviate shear lag according to the location of brace, it gives basic information to preliminary design of high rise building.


When drilling metals, the determination of the axial force is necessary for multiple applications. In the literature the algorithm for calculating the axial force is quite well presented but there is an exception, namely, the correction coefficient of the axial force in relation to the relative thickness of the drill core where several iterations are needed. To determine the relationship between the diameter of the drill and the correction coefficient of the axial force, we start from the expression of the axial force developed based on the hypothesis of polytropic compression of the material to be processed where the correction coefficients are applied when practical situations require it. From the methodology of calculating the correction coefficient in relation to the relative thickness of the drill core it is found that there are three stages. In this paper we eliminate two steps by determining the relationship between the diameter of the drill and the correction coefficient for the relative thickness of the drill core and also improves the calculation both by developing a relationship that can be easily applied and by building a graph that helps upon rapid identification of the correction coefficient.


Immunoglobulin A nephropathy (IgAN) has been recognized as the most prevalent form of glomerulonephritis with various histologic and clinical phenotypes in the world. The Gal-deficient IgA1 with terminally exposed GalNAc residue(s) plays a key role in the pathogenesis of the disease. In this study, a novel colorimetric biosensor based on Helix aspersa agglutinin (HAA) absorbed on polydiacetylene (PCDA) nanovesicles for N-acetylgalactosamine (GalNAC) molecular as core framework of Gal-deficient IgA1 recognition was investigated using the high affinity between lectin HAA and GalNAC. The PCDA nanovesicles were prepared via UV crosslinking. The size, morphology and elastic property of the nanovesicles were tested. The optimal concentration of HAA for the recognition of GalNAC via naked eyes observation was 3 mM and the critical concentration of GalNAC for the sensitive color transition was 2 μg/mL. This novel method has many advantages such as low prices, intuitive, real-time and easy to carry out and great potential in Gal-deficient IgA1 detection.


The goal of this work was to research the influence of athletic, gymnastics and dance content on the motor engagement of preschoolers during individual phases, as well as on the total engagement during directed motor activities. The research was realized during the first term of the 2015/2016 school year in the pre-school institution "Decja Radost" in Svilajnac, and 60 activities of preschoolers were monitored. The time of engagement was measured by random choice of one of the preschoolers and he or she was being monitored by the measurer during the directed activity. The preschooler whose engagement was being measured did not know that he or she was the object of monitoring and measuring. Apart from the descriptive statistics, the One-way ANOVA and Tukey's HSD test were applied in the processing of the data measured in this empirical research. The parameters of the descriptive statistics indicate that the dance content influenced the biggest engagement in the preparatory and the main phase of the directed activity. The elements of athletics were more efficient in the introductory and the final phase, as well as in the total engagement. The average engagement with athletic content is 727.65, and with the dance content it is 718.70 seconds. The values of ANOVA indicate statistically significant difference for all phases in comparison to the content directed to motor activities. The general statement indicates that athletic and dance activities by their content influence more positively the total engagement of preschoolers in relation to gymnastics content.


Objective:To introduce the pharmacological action of Shenfu injection and the clinical practice in cardiovascular disease.Methods:To consult the related articles of recent years and draw a conclusion to them.Results:Shenfu Injection used in protecting the myocardium and preventing myocardium destruction can be demonstrated as these following aspects:reinforcing the contractibility of myocardium,treating arrhythmia,reducing level of the cardiac enzymes,restraining the release of inflammation cytokines and apoptosis factors and regulate ion channels in the myocardial cells,and so on.It can be used to cure congestive heart failure,arrhythmia,acute myocardial infarction.cor pulmonale,dilated cardiomyopathy,viral myocarditis,shock and so on.Conclusion:Not only Shenfu injection can be used widely in cardiovascular internal medicine but also has a bright foreground in cardiothoracic surgery.


The stigma associated with mental illness leads to elevated distress and proves to be a hurdle in the path for treatment. The present study aims to assess the effect of gender and type of illness on perceived stigma and self esteem in people with mental illness. A purposive sample of 137 (53 females, 84 males) patients using cross sectional design was collected from Psychiatric Diseases Hospital and De-addiction Centre in Jammu City. The objective of the study was to assess whether there would be significant difference between female and male participants on the dimension of perceived stigma and self esteem; and whether there exists significant difference between people suffering psychotic disorders and those from neurotic disorders on the dimension of perceived stigma and self esteem. Two way Analysis of Variance was carried out. Results indicated significant effect of gender on perceived stigma but not on self esteem. Type of illness had a significant effect on perceived stigma but not on self esteem. Post Hoc test also revealed that the female participants perceived more stigma due to mental illness than males; and people with psychotic disorders perceived stigma more than people with neurotic disorders. While the stigma of having a mental illness can be demeaning in an unsupportive environment, it also reduces the chance of seeking treatment in an attempt to hide the presence of the illness in turn leading to worsening of symptoms. The need of the hour is to psycho-educate masses about mental illness and associated treatment procedures.


Introduction: The European Space Agency's (ESA) ExoMars Rover mission, to be launched in 2020, plans to investigate the Martian surface and sub-surface for indications of life (biomarkers). One instrument on the rover will be the Raman Laser Spectrometer (RLS), which is a 532 nm (green) laser Raman spectrometer [1]. The University of Kent's Raman Spectrometer is fitted with a 532 nm laser, making it a suitable facility to investigate potential science to come from this instrument. The Raman spectra of carbon is often identified by the presence of the D (at ~1345 cm -1 ) and G (at ~1575 cm -1 ) bands (Fig. 1). Shock effects on spectral peaks have been shown to occur for different minerals [2, 3], e.g. for the mineral olivine impacting on aluminum foils and aerogel [4, 5, 6]. Work involving static pressure and temperature effects on the Raman spectra of carbon have also been conducted [7, 8]. However, the shock pressure and temperature effects on carbon bearing rocks is not well understood. Seeing as carbon is a highly important and abundant element for indications of life it is time that this is investigated.


Abstract. In this study, we analyze the diurnal variations and formation mechanisms of low clouds at different elevations. We further discuss whether there exists a triggering mechanism for convection over the Tibetan Plateau (TP) and whether there is an association among low air density, strong turbulence, and ubiquitous "popcorn-like" cumulus clouds. The buoyancy term (BT) and shear
term (ST) over the TP are significantly greater than those at low elevations, which is favorable for the formation of an increasing planetary boundary layer height (PBLH) and also plays a key role in the convective activities in the lower troposphere. From the viewpoint of global effects,
the triggering of convection by boundary layer dynamics is analyzed over the TP, but also in the Northern Hemisphere over the Rocky Mountains. It is found
that ST and BT are strong over both high-elevation regions. The strong thermal turbulence and large-scale ascending motion jointly result in
obvious positive values of PBLH–LCL (lifting condensation level) under low relative humidity (RH) conditions over the TP. The obvious large-scale subsidence on both sides of the Rocky Mountains, especially the western side, leads to inversion above the PBL and lower RH within the PBL, which further leads to negative values of
PBLH–LCL and decreased low cloud cover (LCC) in most parts of the Rocky Mountains. The slightly greater-than-zero PBLH–LCL corresponds spatially to increased LCC in the partial regions of the central Rocky Mountains. Thus, less LCC is generated at the Rocky Mountains compared to the TP.


To order the complete compilation report, use: ADA398459 The component part is provided here to allow users access to individually authored sections f proceedings, annals, symposia, etc. However, the component should be considered within [he context of the overall compilation report and not as a stand-alone technical report. Taiwan ABSTRACT Four key issues in wavelet zero-tree based image coding are investigates and presented, they are (1) Fast wavelet transform that save 1/2 and 3/4 processing for one dimensional signal and two dimensional signals respectively. (2) The selection of the best wavelet filters that yields best performance (PSNR vs. Bit rate) for most common seen images. (3) Recommendation of number of wavelet scales (or frequencies) for image coding by experiments and analysis.


Abstract
Background: The use of mathematic modeling to better understand the spread of Hepatitis C and
 the impact of interventions can be invaluable for localities, states and countries with a large burden of


The Psycho-Social Characteristics of White Community Organizers and Activists in Interracial Settings January 1981 Paul Christopher Navin, B.A., Franconia College M.Ed., University of Massachusetts, Ed.D., University of Massachusetts Directed by: Dr. Donald K. Carew Twenty-three practitioner-informants were interviewed in depth and were asked to complete Rokeach's (1972) Value Survey in an attempt to identify the motivations for white persons to initiate, continue, and discontinue involvement as activists and organizers in low-income, urban, interracial commionity organizations. In order to create a context for the data, the literature regarding various types of organizers and activists for social change is examined as well as five theories of racial prejudice, the dynamics of major ity-worker/minority-client relationships, and possible new models of behavicr . The interview and Value Survey data are analyzed, compared, and used as a basis for the construction of a profile of an hypothetical "typical" organ izer/activ ist . The informants' characteristics then are analyzed using Hampden-Turner ' s (1971) Model of Psycho-Social Development and it is concluded that informants are creative, productive, psychologically mature radicals who create dynamic, intense existences through their dedication to living by and fighting for certain key principles. Their initial motivations for involvement are found to be primarily


Malignancy of the middle ear is rare and its incidence is 0.18 cases per million people, with its most common type being squamous cell carcinoma. The radiologic, surgical findings, and pathology reports has not been well characterized due to its low incidence. Squamous cell carcinoma in situ of the middle ear is even more so. Here, we report a case of a 69-year-old man who developed squamous cell carcinoma of middle ear 19 months after wide excision for squamous cell carcinoma in situ . The patient received concurrent chemoradiation therapy after revision operation and being evaluated as a stable disease for 30-months follow-up. This case represents the first reported occurrence of squamous cell carcinoma of the middle ear after wide excision for squamous cell carcinoma in situ . A diagnosis of squamous cell carcinoma should be considered in a patient with squamous cell carcinoma in situ of middle ear even after surgery.


We propose a novel model, based on two postulates, which provide new perspective on the fundamental forces using special and general relativity concepts. Many studies address the relations between the particles and the space time manifold, and the latter's physical structure, whether it is Continuous or Discrete. In the proposed model the properties of the particles are classical in the sense of general relativity, whereas their quantum properties are arises due to the experiments.


BACKGROUND : Polypoidal lesions of cervix show various morphological spectrum ranging from inflammatory to neoplastic lesions. In addition to endocervical polyps there are many other polypoidal lesions that appear clinically like endocervical polyps. They are often secondarily inflamed or ulcerated and contain foci of squamous metaplasia. AIM : To study clinicopathological aspects of cervical polypoid lesions. OBJECTIVES : To study the histopathological features of cervical polypoid lesions and to assess their associated clinical features and age wise incidence. MATERIALS AND METHODS: All specimens mentioned as cervical polyp based on the clinical appearance were included in the study. All such polyps from cervix/cervical os were removed and sent for histopathological examination to our department. In some cases we got complete polyp and in some fragments of polyp. All these Specimens obtained with relevant clinical data were formalin fixed and processed with standard procedures. Sections were stained with routine Haematoxylin and eosin stain. We studied various histopathological features and analysed for associated clinical features. RESULTS: During the study period we got 22 cases of cervical polyps. They are common between 20- 50yrs. Common associated clinical features were history of bleeding per vagina or white discharge per vagina. The most common type of polypoidal lesion in this study was classical Endocervical polyp(13). Most of them showed cystic changes and nearly half of endocervical polyps showed squamous metaplasia . Other polypoidal lesions we encountered in this study were Leiomyoma (3), Adenomatous polyp (1), Adenoleiomyoma (1) and Nabothian cyst (2). CONCLUSION: It appears that the entities such as Polypoidal endocervicitis , Endocervical polyp and Fibroepithelial polyp belong to spectrum of a single entity in the pathogenesis process with Polypoidal endocervicitis as initial lesion, Endocervical polyp as intermediate lesion and Fibroepithelial polyp as a last stage in the pathogenesis process of same entity. They need to be removed in symptomatic cases and in cases where there is high probability of harboring malignant foci. Regular followup can be done in other cases. Further large studies needs to be conducted to evaluate various aspects of endocervical polyps.


The purpose of this paper is to present performance characteristics of a quick response digital peak-current-mode 380V dc-dc converter for the green IT system. A proto-type is constructed as the digital control dc-dc converter used in the higher voltage direct current (HVDC) system for the green IT. The proto-type uses the digital peak-current-mode control to show a superior transient response. A dc power supply uses 380V in above HVDC system. The transient response of proto-type is indicated in this paper. As a result, the convergence time and undershoot of output voltage are suppressed to one half and one fourth, respectively.


Purpose – The purpose of this paper is to show how Olin Library has maintained exceptional service to its users before, during and after a periodicals review resulting in deep subscription cuts.Design/methodology/approach – The paper takes the form of a review of activities at the Library during a time of financial restraints.Findings – Although Olin's cancellation project is not entirely completed, there is sufficient anecdotal evidence that the exceptional service has not deteriorated. At some point, soon after the cancellations are in place, a survey should be initiated to confirm this assumption about exceptional service.Practical implications – Several guidelines are presented and discussed that may be useful for other libraries faced with having to make tough periodicals decisions after being directed to cut budgets by their administrations.Originality/value – The paper provides guidelines that should greatly benefit librarians in facilitating a periodicals review and the resulting cuts during diffi...


markdownabstractThis dissertation studies therapist adherence (the degree to which a clinician delivers the specified components of a treatment) from different perspectives. For this purpose, the Dutch Therapist Adherence Measure Revised (TAM-R) was used, which was developed to asses therapist adherence to the treatment model of Multisystemic Therapy (MST). MST is an evidence-based family- and community-based intervention for adolescents with antisocial and/or delinquent behavioural problems aged 12 to 18 years. The TAM-R is routinely collected in clinical practice as part of the quality-assurance system of MST and is used to monitor and improve adherent delivery of MST worldwide.
The __first aim__ of this dissertation was to evaluate what factors affect therapist adherence scores when disseminating evidence-based interventions, as it has proven challenging to implement evidence-based interventions with high levels of adherence into clinical practice. This dissertation assesses the equivalence of the Dutch TAM-R to the American original, and studies the effect of experience on adherence and treatment outcome.
The __second aim__ was to study how adherence and the client-therapist working alliance interact and uniquely and jointly contribute to treatment outcomes. A focus on adherence presupposes that the specific techniques of the intervention are important for achieving good outcomes. Some scholars, however, have stated that
common factors (factors common to all psychotherapy) play a much larger role. The second aim addresses how adherence and alliance interact and uniquely and jointly contribute to treatment outcome.


are culturally shared and mutually comprehensible; indexical signs represent by analogy or action-the weathervane &dquo;represents&dquo; wind direction through its action; iconic signs represent the object itself, as in a picture or photo. The book explores modernity as the antithesis of a community-bounded reality of individual experience. The objection to both of the nominalist perspectives is that culture is conceived as an abstraction-either irrelevant to truth and fact or as creating and reifying truth and fact, necessarily an ultimately relativistic position. RochbergHalton uses some very vivid examples to support his critique of modernism, drawn widely from literature and art as well as sociology and philosophy. From the latter he cites Giddens and Habermas as fellow critics of modernism, but he also uses, to great effect, Moby Dick, analysing the novel as Melville's attack on a narcissistic search for


Abstract
The aim of my paper is to highlight on two works of woman –writers in yiddish literature, The memoirs of Glikl Hamel (1645-1741) and the lightly disguised auto-biographical novel, Deborah, by Esther Singer-Kreitman (1891-1954).The paper also describes the growth of the writers in strictly religious, Jewish families, Glikl´s in Germany, Esther´s in Poland.
Personal crisis were starting-point for their writing, for Glikl the death of her husband, for Esther an arranged, unsuccessful marriage. Glikl wrote for her children about generations of their family. Yikhes, ancestry, were important to Jews. The memoirs also documented contemporary cultural, social and historical cases. Esther´s marriage brought her to a new life in Antwerp and with the outbreak of the World War I to London.
The content of their literary works was personal but reflected firm structures of Jewish life, such as superiority of men to women, sons to daughters, Hebrew to Yiddish. Esther became involved in this. Above all ashkenazi women, especially intellectual, needed education and cultural and political consciousness.
To my help with the paper there are several interesting sources. Look at the list of references!


Subsidence over abandoned mined lands can be attributed to several causes. For purposes of compensation and liability and developing remedial measures, it is essential to identify the real causes. The detailed procedures for a subsidence investigation and the keys to identify and determine the causes and severity of the damages are illustrated and discussed through a case study in this paper. A subsidence check list has been developed for investigation purposes. The case discussed in this paper is a mining-related subsidence. The associated subsidence index was 60%. The damage to the dwelling was due to tension. The major damage was developed within two days. A crackmeter was installed on the exterior wall to monitor the house movement. An inclinometer casing and a Sondex casing were installed in a borehole to monitor the ground movement. The results of the geotechnical instrumentation are presented to illustrate the procedures developed for investigating the subsidence cases over the abandoned mine lands.


Warm mix asphalt (WMA), obtained by means of special bitumen modifiers, such as wax or other organic additives, represents a promising technical solution to reduce the temperatures required for asphalt production and pavement construction. In this experience, an extended program of rheological analyses was carried out in order to evaluate the effects of different type of wax on bitumen viscous flow and dynamic properties at high pavement service temperatures. Five different organic additives, including both natural and synthetic waxes, were considered and eleven bitumen-wax blends were produced and studied using rheological testing. Viscosity measurements performed in the domain of the mixing and paving temperatures have shown essential changes in binders' rheological behavior mainly due to the crystallizing/melting properties of waxes. Changes in viscosity functions depended on the chemical structure of wax as well as on its physical characteristics. However, the viscosity of all blends at 120°C was lower than the viscosity of the base bitumen and the consequent reductions in mixing and compaction temperatures were quantitatively evaluated for all binders. The study of the flow characteristics of the bitumen-wax blends at high pavement service temperatures was carried out using complex viscosity master curves evaluated in the linear viscoelastic domain. Increasing resistance to viscous deformation referable to wax modifications was recorded by analyzing viscoelastic properties in the low frequency domain and different contributions were found with regard to each type of wax. For the polyamidic wax-modified binders, the results indicated the presence of a complex behavior characterized by the absence of a Newtonian region of flow. The final contribution of the experience is related to the development of wax modification of asphalt binders in order to produce WMA for pavement engineering applications.


The Comparison of Mental Health of the Parents of the Who are suffering from Cerebral Palsy with the Parents Normal Children

GH.A.Afrooz, PhD.
H.Hashemi Razini,MA.

The goal of the present study was the compare the mental health of the parents of the children are suffering from Cerebral Palsy with the parents of normal children. This study has been conducted at special schools, private and public clinics which are under supervision on of Tehran well-bing organization the subjects in this study were 7 to 12 years old. To choose samples of normal children parents and suffering from cerebral palsy children parents' random cluster sampling method was used. 94 children that suffer from cerebral palsy and 88 normal children were chosen and there parents were investigated.

In this study SCL- 90-R questionnaire was used to investigate the mental health of the parents to analysis data multivariate analysis of variance (MANOVA) and T-test were used and the result were as follow: A) there is a significant deferens between the different obsessive-compulsive, interpersonal sensitivity, depression, anxiety and hostility in the parents of the suffering children from Cerebral Palsy and the parents of normal children. B) There is a significant deferens between the different obsessive-compulsive, interpersonal sensitivity, depression, anxiety and hostility in the fathers of the suffering children from Cerebral Palsy and the fathers of normal children. C) There is a significant deferens between the different obsessive-compulsive, interpersonal sensitivity, depression, anxiety, hostility and paranoid in the mothers of the suffering children from Cerebral Palsy and the mothers of normal children. D) There is a no significant deferens between the mental health of the fathers and mothers of the suffering children from Cerebral Palsy.
Key word: mental health, Cerebral Palsy, SCL- 90-R questionnaire.


The observed distribution of the number of quasars n as a function of the degree of linear polarization p at 49 cm wavelength is of the form n (p/sub l/ ) approx. exp]-P/sub l//p bar/sub l/], where p/subl/approx. =1.5%. It is shown that such an exponential distribution is given by a model in which the radio- emitting region consists of a large number of segments N approx. =p/subl/$sup - 1$. In each segment the magnetic field is constant in magnitude and arbitrary in orientation. (AIP)


This paper discussed the reasons for the attenuation of the discharge of Hongshan spring through the quantitative and qualitative analyses on the dynamic change of spring discharge. The multivariate statistical regression model of spring discharge responding to four key factors (precipitation recharge, river infiltration recharge, mine discharge and karstic wells exploitation) in two periods was established, and each factor was quantificationally evaluated. The results showed that two reasons lead to the attenuation of spring discharge: the reduction of precipitation and river infiltration recharge, as well as the increase of mine discharge and karstic wells exploitation, which play the main role in the attenuation.


Starch is a significant ingredient of the seed endosperm with commercial importance in food and industry. Crop varieties with glutinous (waxy) grain characteristics, i.e. starch with high amylopectin and low amylose, hold longstanding cultural importance in some world regions and unique properties for industrial manufacture. The waxy character in many crop species is regulated by a single gene known as GBSSI (or waxy), which encodes the enzyme Granule Bound Starch Synthase1 with null or reduced activity. Several allelic variants of the waxy gene that contribute to varying levels of amylose content have been reported in different crop plants. Phylogenetic analysis of protein sequences and the genomic DNA encoding GBSSI of major cereals and recently sequenced millets and pseudo-cereals have shown that GBSSI orthologs form distinct clusters, each representing a separate crop lineage. With the rapidly increasing demand for waxy starch in food and non-food applications, conventional crop breeding techniques and modern crop improvement technologies such as gene silencing and genome editing have been deployed to develop new waxy crop cultivars. The advances in research on waxy alleles across different crops have unveiled new possibilities for modifying the synthesis of amylose and amylopectin starch, leading to the potential creation of customized crops in the future. This article presents molecular lines of evidence on the emergence of waxy genes in various crops, including their genesis and evolution, molecular structure, comparative analysis and breeding innovations.


The continuing Irish tragedy is reflected strongly in the Republic of Ireland's broadcast news service, here described (based on first hand observation and interviews) by Dr. Orlik, a professor of broadcast and cinematic arts at Central Michigan University. Since the manuscript was edited, the Irish government has cracked down still further, having banned direct or secondary coverage of activities of members of the political wing of the IRA, as well as of three extremist Protestant groups in Northern Ireland. This research was supported by a University Achievement Award—and the cooperation of Louis McRedmond of RTE, Dublin.


Most criminal systems adopted "Criminal Transaction" in simple crimes; such as Petty Offences and some Misdemeanors. However, modern policy in these legislations has adopted this system "Criminal Transaction" in Economic Crimes. This is one of the most scientific development in criminal features. This type of crimes arises as a result of the importance of looking for new ways to deal with criminal disputes, as well as to stop criminality without going through classic Criminal Process. The main idea of "Criminal Transaction" is to make the priority to state finance and state economy before punishment. So it is withdrawing of Criminal Prosecution, by the society, or suspension of punishment, according to circumstances, for the amount of money settled on. This study will concentrate on all of these aspects. Besides different countries and laws which adopted this system, and the conditions of "Criminal Transaction", methods and procedures. As a conclusion, advantages and disadvantages of "Criminal Transaction" are identified, also the importance of putting this system in practice is emphasized, but by taking


3 Florian Altermatt1,2,* & Emanuel A. Fronhofer1,2 4 5 1 Eawag, Swiss Federal Institute of Aquatic Science and Technology, Department of 6 Aquatic Ecology, Überlandstrasse 133, CH-8600 Dübendorf, Switzerland. 7 2 Department of Evolutionary Biology and Environmental Studies, University of 8 Zurich, Winterthurerstr. 190, CH-8057 Zürich, Switzerland. 9 10 *corresponding author: firstname.lastname@example.com 11 12 13 Number of words: 7700 14 Number of figures: 6 15 Number of tables: 4 16 17


Although some important precedent works already called attention to the theme and, in a certain way, foretold a delineation of the object, it may be said that Warren Dean's With Broadax and Firebrand (1995) and Shawn Miller's Fruitless Trees (2000) are the real founders of Portuguese America's forest historiography. Dean and Miller have established the general parameters for the study of colonial Atlantic Forest from the point of view of politic-economical processes of appropriation and use of environmental resources, both concerning the forms of approach and the explicative hypotheses. Notwithstanding, these two works do not incorporate the powerful trend, observed in the last decade, of a colonial economy's approach strongly influenced by author such as Marcel Mauss, Karl Polanyi e Giovanni Levi, generating a great revision on the determinants of Luso-Brazilian economy. This article aims itself a critic of forest historiography such as sketched out by Dean and Miller from the prism of this economic-substantivist attitude.


PURPOSE
The perspectives of patients with cancer about their treatment can inform interventions to improve the approaches of treating oncologists and experiences of future patients. We sought to identify areas where current toxicity management, informed consent processes, and physician-patient communication merit improvement.

METHODS
In a Web-based survey administered from March to May 2018 using quota-based sampling to draw a nationwide sample of US patients with cancer treated with radiotherapy within the past 5 years, we evaluated patient perceptions of adequacy of information about adverse effects, severity of actual adverse effects experienced, and experiences divergent from expectations.

RESULTS
Among 403 respondents, 18% felt inadequately informed about what adverse effects to expect from radiotherapy, and 37% experienced radiation adverse effects that they wished they had known more about. Similar proportions of patients treated with chemotherapy (36%) and surgery (34%) experienced toxicities related to those treatments that they wished they had known more about. Patients who noted their adverse effects to be minimal versus severe were significantly more likely to feel informed about radiotherapy adverse effects (odds ratio, 13.05; 95% CI, 5.6 to 30.38; P < .001). Across all evaluated measures, a majority of patients indicated that they did not experience the potentially anticipated radiotherapy adverse effect or that it was the same as or better than expected.

CONCLUSION
This study suggests that experiences with radiation adverse effects generally are congruent with expectations. Nevertheless, improvement of pretreatment counseling across all cancer therapy modalities seems warranted to improve informed decision making and treatment experiences.


The paper shows, with an example and a generalized discussion, the effect of stray capacitance in various parts of the antenna circuit upon the observed circuit resistance. Stray capacitance at the base of a capacitive antenna decreases the apparent antenna resistance while in the case of an inductive antenna it increases it. A method of approaching the true resistance of an antenna in the presence of stray capacitance is presented, and the possibility of extending its use to the measurement of the high-frequency resistance of coils is pointed out.


Engineers today are often required to make critical judgements involving decisions that extend beyond traditional discipline boundaries requiring ongoing learning, much of which is informal, learnt on the job from peers who are often from different disciplines. To prepare students for professional practice, they need opportunities to experience, practise, reflect and improve their ability to work in a collaborative environment. The University of Technology, Sydney teaches an undergraduate engineering science programme in Hong Kong. The authors have found it initially difficult to get students to participate in collaborative learning activities and in particular those that involved students in using their own judgement or critical analysis. In response, the authors redesigned their course to integrate collaborative peer learning activities into all areas of the curriculum including collaborative problem solving exercises that are subsequently assessed through a series of first individual then collaborative quizzes (using the immediate feedback assessment techniques (IF-AT)) and exams. Initial results from students overwhelmingly showed that the collaborative activities improved their understanding, ability to think through and resolve problems, and the identification and addressing of gaps in their learning. This approach has potential to benefit all engineering students as it prepares students to make the most of the informal collaborative learning opportunities provided in professional practice while simultaneously enhancing their ability to undertake lifelong learning.


Most of the eruption cysts occur either singly or in some rare cases simultaneously in two regions. This is an extremely rare case documenting the occurrence of four simultaneously occurring eruption cysts, all in the posterior molar region, in an 18-month-old male patient. These lesions were causing a lot of discomforts as well as feeding and obvious esthetic concerns for the patient. This paper documents the pathogenesis, clinical presentation, and treatment for this extremely rare case.


I find the sensitivity experiments very interesting and the results can contribute to our understanding of the impact of climate change in the northern North Atlantic. However, some aspects of the design of the experiments need to be clarified, including the sources of freshwater discharge, and also I find that some of the interpretations of the results needs to be clarified or modified, as I describe below. Finally, I have some minor comments. When these issues have been clarified I can recommend publication in Ocean Science.


The brightest representatives of the national historiography of the 17th – 18th centuries are the so-called Cossack Chronicles. These texts, written by the Cossack elite of the Hetmanate, serve as an excellent historical source for exploring the historical and social and political thought of the epoch of Bohdan Khmelnytskyi. The writings of the Military Chancellerists are complex structures that are on the verge of history and literature, and the term Chronicles have been used by their first publishers.

From the whole multiplicity of Cossack Chronicles, the most famous and original are the works of Eyewitness, H. Hrabianka and S. Velychko. The article shows the peculiarities of research and perception of these historical texts in the works of scholars of the mid-19th – beginning of the 20th centuries. The first scientific researches of Chronicles by their publishers, special studios of historians and literary critics on the phenomenon of creativity of Military Chancellerists are analyzed. The perception and use of Cossack Chronicles in writers are disclosed. Particular attention is paid to those works where Cossack historical and literary works are the main subject of research.

The article shows priority subjects for the study of Cossack chronicles. Most of the research attention was given to the source studies of Cossack historical works. In particular the leading topics were the source value of the Chronicles, the structure of the works, the source base used by the historians of Hetmanate and the attempts to extract the original text from numerous copies later ones of the works. Scientists also investigated the attribution of Cossack Chronicles, the situation of the creation of works and the ideology of their authors. But mostly these topics will be leading for Soviet and contemporary Ukrainian historiography. The transformation in the perception of the 19th – beginning of the 20th centuries researchers of the literature of the Chancellerists – from sources of factual information to literary and fictional, heroic history are analyzed.


With the classification of ultrashort‐pulse laser processing systems as "systems for the generation of ionizing radiation" in the German Strahlenschutzgesetz (Radiation Protection Act), their operation is usually no longer possible without a license and without notification of the authorities. This article deals with the implementation of the legal requirements resulting from this classification in an industrial production environment.


The typical metallic parts fallures occurred on utility boilers,such as short-time overheat.long-time overheat,abrasion demage,tensile crack of wall entrance tube,cracking in weld joints of non-similar steels,cracking due to thermal fatigue,cracking on bends of austenitic stainless steel,etc.,have been analysed,and measures for preventing from above-mentiond failures being given out.


Among the information acquisition costs, it is most important to present private benefits.This increases incentive costs and is a negative effect of private benefits.However,private benefits of control reduce the agent incentive to forecast a failure without enough information. This decreases incentive costs and is a positive effect of private benefits. The delegation of information acquisition and incentive depend on the cost of information acquisition cost and the net effect of private (benefits) on the process of decision-making of project investment.


32 SD female rats were divided into four groups in random order,which were resting comparative group(C_1),resting and being taken drug comparative group(C_2),only exercise group(T_1),exercise and being taken drug group(T_2) to observe the effects of Xuefuzhuyu decoction on hemorheology and sports capability after exhaustive swimming in untrained rats.Results:(1) After untrained rats had been taken drug for seven days,the hemorheologies of C_2 were also signigicantly better than those of C_1;The swimming times to exhaustion of C_2 were signigicantly longer than those of C_1;2) At immediately post exhaustive swimming,the hemorheologiex of T_1 and T_2 were less than those of T_1.Conclusion: Xuefuzhuyu decoction could significantly enhance the blood rheology and exhaustive swimming capacity in untrained rats,and reduce the abnormal change of hemorheology in untrained rats at immediately post exhaustive swimming.


In the article the authors carry out analysis of methodical approaches to the evaluation of investment scientific and technical projects. The first approach aims to risk assessment, other – orient to comparative effectiveness assessment investment scientific and technical projects. The authors release risk of social, perceive and commercial scientific and technical projects, fulfill analysis method of risk assessment and risk calculation, comparative analysis method of define discount rate at investment planning and method of comparative effectiveness assessment of investment scientific and technical projects. The authors modify index of Net resent value NPV introduce valuation of risk for commercial scientific and technical projects and index of reduced costs for evaluation costly scientific and technical projects. It will allow to create conditions for finishing of scientific and technical projects before practical introduction and to provide productivity and competitiveness of scientific and technical development.


The aim of this research is to examine the dimensions of junior high school teachers? readiness for implementing a flipped classroom approach and to construct and validate an instrument?the Flipped-Classroom Teacher Scale (FCTS). Two sets of samples (170 and 495 junior high school teachers) served to explore and confirm the constructs of the FCTS model proposed by this study. The model has been empirically validated via exploratory factor analysis (EFA) and confirmatory factor analysis. The research participants were from different geographical locations in Taiwan. The FCTS consists of four factors: institutional support, technology self-efficacy (TSE), teacher beliefs and teaching strategies (TS). The results show that the FCTS model is a valid and reliable scale. Teachers may use the FCTS to gain a greater understanding of their instructional design and strategies in relation to flipped classrooms.


In gld mice, CD4 and 8‐double‐negative (DN) T cells as well as naive and memory‐phenotype T cells accumulate in the peripheral lymphoid organs. Although Fas ligand (L) defect accounts for the progressive accumulation of abnormal DN T cells, the existence of other mechanisms which may be involved in the defective homeostasis in gld mice has been unclear. In this study, we analyze T‐cell homeostasis in gld mice using adoptive transfer systems. It was shown that a gld, but not C57BL/6 (B6), environment led to augmented proliferation of B6 T cells transferred without up‐regulation of CD69. Thus, the augmented T‐cell proliferation seemed to result from mal‐homeostatic proliferation even in the presence of a large number of recipient T cells. T cells from lpr mice showed no significant proliferation in the B6 environment, suggesting that the absence of Fas‐Fas L interaction was not responsible for the mal‐homeostatic proliferation. Although similar levels of IL‐7 mRNA were detected in gld and B6 spleens, the intensity of CD127 and the proportion of CD127+ cells in the T cells were significantly lower in gld mice than in B6 mice, suggesting that IL‐7 excess in a gld environment is responsible for the abnormal proliferation of transferred T cells. The administration of anti‐CD127 antibody inhibited the proliferation of transferred lymphocytes. Thus, IL‐7‐dependent proliferation seems to be involved in the abnormal proliferation of lymphocytes in gld recipients.


This paper presents an asynchronous implementation of ARM9 processor, AEM32. We introduce an adaptive pipeline structure that makes the pipeline depth dynamically. We employ a parallel processing control based on datapath splitting to execute the instruction fed into the pipeline in parallel when they have different datapath. AEM32 is synthesized using a 0.35-µm CMOS cell library. Simulation results show that our implementation had 2.6 times higher performance than the asynchronous counterpart, AMULET3i. In terms of Et2, AEM32 shows 3 times higher efficiency than the other counterpart, ARM966HS.


A new multidomain direct (noniterative) method for solving boundary-value problems is presented. Using this method, the solution is expressed by a linear combination of auxiliary functions and unknowns which pertain to the boundaries of a subdomain. This approach enables us to solve problems independently and exactly, without any iterations between subdomains. As a consequence, different types of equations and coordinate systems may be considered in different subdomains. Moreover, different boundary conditions and variable (in space) time steps may be imposed on the subdomains as well. Applications are given for initial boundary-value problems with known analytical solutions, including a highly nonlinear porosity equation. © 1994 John Wiley & Sons, Inc.


11054 Background: Routine prophylactic administration of recombinant granulocyte colony-stimulating factor (G-CSF, filgrastim) has enabled more frequent scheduling of adjuvant cytotoxic drugs in primary breast cancer. Dose-dense chemotherapy of this kind has become popular in recent years, but few studies have compared the costs and benefits of this treatment approach. Methods: We conducted a retrospective comparison of 150 Hong Kong Chinese primary breast cancer patients treated with either conventional 3-weekly chemotherapy or G-CSF-supported 2-weekly (dose-dense) chemotherapy using similar cytotoxic regimens (four cycles of doxorubicin and cyclophosphamide, followed by four cycles of taxane) between April 2004 and May 2006 in two teaching hospitals. Assessments of treatment tolerance, toxicity, scheduling, and expense were applied to both patient cohorts. Results: Compared to conventionally treated patients (n = 117), dose-dense patients (n = 33) benefited from 52.3% fewer chemotherapy delays (21.2% vs...


In cryptography, public key cryptography plays an important role to communicate sensitive information in online payment or any other electronic transactions securely. This paper illustrates the major applications of public key cryptography and their functioning process. The real time applications of public key cryptography are also included here


ABSTRACT A mixture of myo-inositol and inorganic metaphosphate (prepared by freeze drying an aqueous solution at pH 4) produced, upon warming, in moderate yield every inositol monophosphate ester, thereby providing in a single step a complete library of these compounds. The individual inositol monophosphates, both meso-compounds and racemic mixtures of the two pairs of enantiomers, were isolated by ion-exchange chromatography which was facilitated by the addition of borate to the mobile phase. The phosphates were characterised using phosphorus analysis in conjunction with alkaline phosphatase, mass spectrometry and 1H NMR spectroscopy.


i.1653, Portrait of Mary Forrest, niece of Cornelius Humphreys. Donated by the Willis family, 4 July 2013, the group of portraits came to the Willis family via the Taylor family of Ongar. Charlotte Willis's grandfather's first wife, Charlotte Mary Taylor, was the great granddaughter of Mary Forrest and Charles Taylor. Mary Forrest, Humphreys' niece, married her uncle's friend, Charles Taylor (1756–1823) artist, engraver and author, in 1777. Before this she lived with her aunt and uncle in the Tower of London.