Terfa W. Assistant Professor Abstract A cross sectional study was conducted from July to November, 2013 to determine the prevalence of coccidiosis, to identify species of Eimeria and to assess potential risk factors in and around Ambo town, Ethiopia. The study involved anteand post-mortem examination, mucosal scraping examination using floatation technique, gross and histopathological examination and identification of Eimeria species. Out of 390 examined chickens, 18.7% (73/390) harbored different Eimeria species. Five Eimeria species, Eimeria tenella, Eimeria necatrix, Eimeria brunetti, Eimeria maxima and Eimeria acervulina with the prevalence rate of 62.2%, 18.29%, 10.98%, 6.09% and 2.43%, respectively were identified 82 times from positive chickens. Eimeria tenella was the predominant species while Eimeria maxima and Eimeria acervulina were the least prevalent species. There was no statistical significant difference between age ( χ=0.921, p>0.05), breed ( χ=0.16, p>0.05), sex ( χ=3.609, p>0.05) and management system ( χ=2.245, p>0.05) groups. In conclusion, the present study showed that coccidios is is an important disease of poultry in the study area. Thus, awareness creation, implementation of appropriate management system, economic effects and further studies on molecular characterization and drug sens itivity of the Eimeria species in the study area were recommended.


one volume a unique, resourceful, and selectively comprehensive overview of the relevant history and literature. The qualifier "Arabic" in the title justifiably comprehends not only Islamic but also Christian and Jewish contributions. As for the term "philosophy", it may, however, not be so justifiable despite the fact that the introduction of Arabic philosophy was closely knit with the introduction of other Arabic learning. The topic of Arabic philosophy is, contrary to what the reader of the title would expect, neither exclusive nor systematically comprehensive. Instead, it covers some of the several topics that the Arabic term 'Urn (learning or knowledge) refers to, that is, not only to the philosophical 'Urn alfalsafa) but also to the strictly scientific learning (e.g. 'Urn al-tib and 'Urn alfalak) and other learning (e.g., Arabic language, Sufism and the least popular in medieval Christian Europe, 'Urn al-kal&m) as well. Although the essays provide considerable primary and a greater number of secondary sources, one may expect from some essays more references to the original Arabic sources and, when appropriate, a textual analysis and comparison. One may also notice the almost unavoidable lack of uniformity in the research approaches and exposition styles in essays written for an international conference. One may, moreover, wonder why there is no index and not even one article in Italian, the language of honored University of Bologna. A number of mechanical errors are found. There are some incorrect idiomatic expressions (page 20, paragraph 2, line 2 corrected version: "he was [still alive]" and 138,3,1: "Le movement de traduction de l'arabe [au] latin..."); some typographical errors (38,3,1: Apr[e]s; page 45, note 21, line 3: the hamzah in "unshi'a;" 135,3,2: d[6]favorables; 147,3,7: a commen[c]6; 102,3,5: Aust[r]oHungarian; 122,4,11: [ejtudes; 122,5,2: Italian sentence making no sense, should at least begin with: Inventario de[i] libri... ) The translation of "Muntakhab" is not "summary" (p.66, n.8) but "selection." The use of the term "heresy" (87,3,8 and 88,1,1) is incorrect; Miklds Mardth uses the term correctly in his essay (104,3,5). The so-called "University of Beirut" (92,3,3) does not exist; the reference may be to the American University in Beirut. Finally, the introduction, written by Charles Butterworth alone, raises the question about the non-conspicuous contribution of the co-editor Blake Andree Kessel, whose field and specialty are not relevant to the topic of the book. It also reveals a couple of minor errors in dating time periods (3,2,16; and 4,1,8).


Previously unpublished new projects are thematically integrated into the evolution of Baur's oeuvre. The book thus reveals a conceptual and design constant, or even fascination, in the work of Ruedi Baur. Thus the book reveals a conceptual and design constant, or even fascination, in the work of Ruedi Baur. Five years after the success of Ruedi Baur, Integral et associes, the author takes stock and manifests the principles of his design work and attitude. Five years after the success of Ruedi Baur Integral et associes, the author takes stock and manifests the principles of his design work and attitude. "


The identification of specific morphologic diagnostic criteria is of paramount importance to optimize the accuracy of fine‐needle aspiration cytology (FNAC) and to reduce the rate of false‐negative results. In the current study, the authors reviewed a consecutive series of false‐negative findings observed in the study center to define the presence and degree of cytologic abnormalities. False‐negative cases were randomly mixed with true‐negative cases and were reviewed by a panel of expert readers in a blinded fashion. The main objective of the current study was to identify a morphologic pattern that may permit the reduction of false‐negative findings while maintaining the specificity of FNAC.


The role of the university in improving the regional quality management systems of higher education has been discussed. The version of a model of regional quality management system of higher education in compliance with international standards of quality management system has been presented.


DISCLAIMER This report describes a proof-of-concept system, developed to demonstrate the technical feasibility of implementing a Tablet PC-based electronic accident reporting form. This system is intended for demonstration purposes only. This is the fourth of four project reports and is not intended as a summary of the all activities conducted during this project. Its scope is limited to the proof-of-concept system and the relationship of that system to prior research. an electronic software-based version of a standard accident report form was implemented for the sake of demonstration and proof of concept on a Tablet PC platform. Previous efforts resulted in a working PC-based version that was not optimized for the Tablet environment and another version for a Pocket PC that was abandoned due to the complexity of the form and lack of screen space on the Pocket PC. While the PC-based version could function on a Tablet PC, its lack of support for native tablet features such as handwriting recognition and " ink " –based drawing limited its viability. Thus, this version was produced to capitalize on Tablet PC features and to expand on the work that was already done. A Tablet PC and a connected, external GPS were used for development purposes. For a production version of the system, these would be replaced with " rugged " equivalents. For the sake of simplicity, data communications capability was not implemented via hardware or software. This would also be desirable in a production system. In a related project, Redding Responder, these aspects have been addressed for a California Department of Transportation (CALTRANS) application. The results of that project are directly applicable to this project. A standard accident report form was analyzed and form fields were grouped functionally. The functional grouping of form fields provides for a more logical and intuitive user interface in the electronic version. This eliminates clutter by presenting smaller, related sections of the form together for completion and quick access. The resulting program allows for the entry of all information using pen input. A benefit of using pen input exclusively is that the form can be filled out entirely by using the Tablet PC in tablet mode. A responder could carry and use a rugged Tablet PC at the incident scene, outside a vehicle, and complete the form without a need to " dock " the unit and use a keyboard. Furthermore, the pen is a more natural …


Marchiafava Bignami disease (MBD) is a rare disorder, first described in 1903 by Marchiafava and Bignami and characterized by primary progressive demyelination and necrosis of corpus callosum presenting clinically with multifocal central nervous system signs along with altered mental status and seizures. The exact pathology leading to MBD has not yet been elucidated. Classically, chronic alcoholism and vitamin deficiency have been implicated. Recently, MBD is hypothesized to result from an autoimmune insult or part of a para-neoplastic syndrome. Here, we present the case of a 33-year old male who had history of chronic alcoholism with acute pancreatitis presenting with MBD.


The JCT sealing glue is high in strength,small in shrinkage,low in viscosity with good mechanical properties and easy to construct.It can be used for reinforcing the concrete structures,especially in extensive application to strengthening the deck slabs(or beam) and culverts.This article analyzes the factors causing cracks of pipe culverts,with presentation of construction technology for repairing cracks and strengthening the pipe culverts with sealing glue in high permeability and high strength.


IT HAS OFTEN BEEN SAID THAT AIR POLLUTION WILL HAVE A DETRIMENTAL EFFECT ON RESIDENTIAL PROPERTY VALUES. THE EVIDENCE, HOWEVER, IS QUITE SKIMPY. URBAN LAND ECONOMISTS AND REAL ESTATE APPRAISERS HAVE FROM TIME TO TIME MADE GENERAL COMMENTS THAT NUISANCES, INCLUDING AIR POLLUTION, MADE A NEIGHBORHOOD A LESS DESIRABLE PLACE IN WHICH TO LIVE. THIS PAPER IS A THEORETICAL ANALYSIS OF HOW TO MEASURE THE RESULT OF ATTEMPTS TO ESTIMATE THIS IMPACT IN A MORE EXTENSIVE STUDY TO ESTIMATE THE SOCIAL COSTS OF AIR POLLUTION NOT INCURRED BY FIRMS CAUSING THE POLLUTION. IN THE FINAL SECTION OF THE PAPER THE RESULTS OF THE STATISTICAL STUDIES ARE PRESENTED. /AUTHOR/


New specialty oligomers were developed to increase adhesive performance in low viscosity UV/EB curable laminating adhesives for glass. Sample formulations will be discussed including refractive indices, transmissions, clarity and surface tensions of glass and adhesives, along with environmental conditioning of laminate structures. Adhesive testing results will also be covered. Introduction Due to the huge demand for transmission and clarity, an optically clear adhesive is required for many types of applications. The goal of this work was to design optically clear UV/EB curable lamination adhesives for all types of glass laminations. Moisture absorption also plays a key roll in the overall clarity of the laminations. UV transmission is the best method to study the laminates' performance. Prior to reviewing the adhesion tests, UV energy, photoinitiator selection and various types of UV energy absorption will be covered. Photoinitiator Selection Previously, studies have been done to determine the correct photoinitiator for three different UV energy lamp sources – H-bulb, D-bulb, and V-bulb. Different bulbs emit different wavelengths of energy and therefore respond to the photoinitiators differently. The UV wavelength range is from 200 to 425 nm. Three different photoinitiators listed in Table 1 show both the importance of photoinitiator and UV energy source. The photoinitiators chosen are Esacure KIP150, Irgacure 819 and Irgacure 2022. Table 1 shows the chemistry and the absorbance of each photoinitiator. Table 1 – Photoinitiators Trade Name Chemical Name UV Absorbance Esacure KIP150 Oligo [2-hydroxy-2-methyl-1-[4-(1-methylvinyl) phenyl] propanone] 240-320 Irgacure 819 Bis (2,4,6-trimethylbenzoyl)-phenylphospineoxide 360-390 Irgacure 2022 Bis (2,4,6-trimethylbenzoyl)-phenylphospineoxide (20%) and 2-hydroxy-2-methyl-1-phenyl ketone (80%) 360-390 240-320 The most common bulb used for curing in the UV industry is a medium pressure mercury bulb, or Hbulb. The typical spectral distribution emitted from an H-bulb is shown in Figure 1. An overlay for the three photoinitiators' UV absorption is also shown in the figure.


The purpose of the present invention is to provide a modified acrylic resin cured product, particularly, a modified acrylic resin film, having excellent lubricity and excellent transparency, and a laminate including the modified acrylic resin film. The modified acrylic resin cured product (C) according to the present invention is obtained by treating the surface of a cured product (X) comprising an acrylic resin by using a compound (A) containing, in each molecule, one or more anionic hydrophilic groups forming an ion pair with an onium ion of an amino silicone, and one or more groups selected from the group consisting of a group containing a polymerizable carbon-carbon double bond, an amino group, a mercapto group and a hydroxy group.


As new data reveals a threefold increase in Acanthamoeba keratitis infections in South-East England contact lens wearers have again been warned about the risks posed by water supply and poor compliance. Joe Ayling reports


The transition-metal catalyzed addition of heteroatom nucleophiles to aryl and vinyl halides is reviewed. This chemistry typically involves a nickel- or palladium-based catalyst containing phosphine ligands. In recently developed palladium-catalyzed chemistry, aryl halides react with amines in the presence of base to form arylamines. In similar chemistry catalyzed by both nickel and palladium, aryl and vinyl halides react with alkali metal or tin thiolates or selenides to form aryl and vinyl sulfides, while the reaction of different phosphorus compounds, such as phosphides, phosphonates, and phosphonites, with aryl halides gives compounds with new aryl-p· linkages. In addition to these typically nucleophilic heteroatoms, electrophilic heteroatoms such as boron, silicon, tin, and germanium have also been coupled to aryl electrophiles. The review closes with a brief summary of the general reaction pathways of these C-X bond-forming processes.


This paper presents a methodology to estimate the calibration of a network of cameras, possibly with nonoverlapping fields of view. Calibration comprises both the intrinsic and extrin sic parameters of the cameras and is based on a mobile robot with the capability of estimating of its pose in a glob l frame. The robot is equipped with one calibrated camera which we assume that can be oriented in a manner to observe world points also seen by the network of cameras. Our methodology is based on matched scale invariant features (SIFT) r econstructed to 3D points using e.g. SLAM, and focus on the problem of transporting the robot coordinate sy stem to the fixed cameras. The reconstructed 3D points and their images on the fixed cameras are propo sed as a solution for the calibration problem. In order to test the validity of our methodology we constructed a V RML scenario, thus having low noise images and ground truth information. Results show the successful calibration of three fixed cameras using a mobile camera that acquired about thirty images.


Physiological processes in cervical squamous epithelium have not been extensively studied. Perhaps understandably, most of the research has concentrated on the pathology of the cervix, in particular dysplasia and malignancy. Fluid‐phase endocytosis is a physiological process which has been demonstrated to be important in understanding disease development at other squamous epithelial sites, e.g. oesophagus. In this study, we have demonstrated by a new methodology developed in our laboratory using fluorescent microspheres and flow cytometry that fluid‐phase endocytosis occurs in cervical squamous cells. The process has been shown to be dose‐ and time‐dependent. This novel approach provides a means to improve our understanding of the physiological functions of the cervix and may provide insight into the pathogenesis of cervical neoplastic and non‐neoplastic disease.


ABSTRACT: Terraces usually reduce sheet and rill erosion between terraces and trap part of the eroded soil by deposition. The benefit of this deposition in reducing soil deterioration from erosion depends upon both the amount of deposition and terrace spacing. To determine P-factor values for terraces, field data were analyzed to derive an equation for deposition, as affected by terrace grade, that can be combined with a relationship for benefit from deposition. These values are used in conservation planning as part of the universal soil loss equation to estimate the reduction in soil loss produced by terraces.


It has been demonstrated that the direction and magnitude of transition dipole moments, and hence rates in the excitation energy hopping in the self-assembled porphyrin boxes can be tuned by insertion of ethynyl groups as well as the dielectric constant of solvent.


Background: Transcriptional 'cell states' (defined as the genes expressed in a cell in any given point in time) can determine response to targeted and immune-based therapies in late-stage melanoma treatment. MITF and AXL are common markers of drug-sensitive and drug-resistant 'cell states', respectively; and extensive heterogeneity of both cell populations have been observed in melanoma cell lines and tumors. Understanding the mechanisms controlling these 'cell-states' may lead to therapeutic strategies to overcome resistance and improve patient survival. Problem: To date, certain experiments assessing cell population heterogeneity dynamics in melanoma (such as live cell sorting applications) has been limited by the lack of surface markers defining the MITF 'cell-state'. Furthermore, existing antibodies against MITF commonly detect multiple expressed isoforms which can limit the accuracy of downstream experimental assays, such as in-cell western blot detection. Methods and Results: To find a suitable cell surface marker defining the MITF 'cell state', we used the PARIS GenePattern module with data from the Cancer Cell Encyclopedia. TNFRSF14, our highest ranked gene, was highly correlated to MITF transcript expression in melanoma cell lines. We confirmed this at the protein level through western blot detection and flow cytometry. Using flow cytometry, we could accurately follow 'cell-state' population dynamics of AXL and MITF following shRNA knockdown of MITF and during acquired drug resistance in culture. Outcomes: We have identified TNFRSF14 as a robust cell surface marker of MITF in melanoma. Our TNFRSF14 and AXL live cell flow protocol will be useful for those exploring 'cell-state' population dynamics and heterogeneity in melanoma and could contribute to new mechanistic insights of drug resistance. Citation Format: Ken Dutton-Regester, Nicholas K. Hayward. TNFRSF14 is a cell surface marker of MITF expression in melanoma [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 4226.


Was Stalin a weak dictator? This sort of question is more familiar to students of Nazi Germany, who have pondered the nature of Hitler's power since the late 1960s. Like the more liberal historians of the Soviet Union at the time, many historians of Nazi Germany were troubled by the inadequacies of the totalitarian model, which emphasized the boundless power of the dictator. Studies of the Nazi system increasingly observed the disintegration of government rather than the concentration of power in the hands of an autocratic regime in the 1930s. They pointed out that the system was ruled by a fluid aggregation of special commissions and other ad hoc organizations rather than a stable hierarchical bureaucracy.1 Some historians concluded that the coordination of these institutions was nevertheless the core of Hitler's power, that bureaucratic chaos was part of a strategy of divide and rule.2 Others observed his aversion to fundamental decisions, even to decision making in general, and concluded that institutional leaders and other special interests often played the dominant role in decision making. Most famously, Hans Mommsen, in his Beamtentum im Dritten Reich, suggested that Hitler was a weak dictator.


Abstract Elastomers are commonly used as electrical insulators in marine acoustic devices. A previous paper discussed the very large decrease in electrical resistivity of a Neoprene GRT formulation when subjected to moderately high molding pressures. In the present paper, data will be presented showing similar dependencies on mold pressure for natural, polybutadiene, 39%-acrylonitrile NBR, and chlorobutyl elastomers and the absence of the effect for an EPDM, and a 27%-acrylonitrile NBR elastomer. These data are not easily explained. The previous paper also discussed that increasing the carbon-black loading caused the electrical resistivity to decrease at even lower molding pressures. Similar trends are presented here for the other elastomers whose electrical resistivities are dependent on molding pressure. Data will also be presented that show that the addition of poly-para-dinitrosobenzene (Poly DNB®) to a CR formulation will eliminate the mold pressure vs. electrical resistivity effect.


This paper focuses on the general methods used in guides developed for the energy efficient design and inspection of new and revitalized housing projects for military family housing. The methods and guides can also benefit the wider market of public and other housing. Inspections performed on military and public housing units were used to identify energy deficiencies. The most common problems found were related to disconnected and deteriorated forced air distribution duct work and poor system design resulting in significant air leakage. Design and inspection guides are summarized for new construction and revitalization projects. 7 refs., 7 figs.


Escola de Engenharia Graduate Program in Electrical Engineering A Practical Toolset for TERS Experiments and Analysis by Hudson Luiz Silva de MIRANDA This work proposes a set of hardware and software tools to improve the usability of tip-enhanced Raman spectroscopy (TERS) systems. TERS is capable of providing optical images with resolution beyond the light's diffraction limit while also providing chemical and structural information, which makes it a technique of interest for nanoscience and nanotechnology applications. Specifically, this work aims to develop hardware and software solutions to better understand the TERS probe's interaction with an electromagnetic field, providing insights on: optical probe alignment methods, optimization of probe's constructive parameters and super-resolution. Aside from the development of the necessary instruments, this task also comprehends the study of TERS probe's interaction with light via Finite Element Method simulations in addition to TERS experiments with graphene under a series of environmental conditions that affect the local electromagnetic field in a controlled manner. Furthermore, the work also comprehends the use of data analysis techniques, specifically Spectral Unmixing and Principal Component Analysis (PCA), with the objective of efficiently extracting information from hyperspectral images in a non supervised manner via dimensionality reduction.


Certified that the thesis entitled "Comprehensive Testing of Embedded Systems Through Architectural Frameworks and Models" submitted to Acharya Nagarjuna University for the award of Ph.D. degree in the Faculty of Computer Science and Engineering is a bonafide record of research work done by Mr. K. Rajasekhara Rao under my supervision and guidance and that the thesis has not previously formed the basis for the award of any degree, diploma, associateship, fellowship or similar title to the candidate


This paper introduces an adaptive time splitting technique for the solution of stiff evolutionary PDEs that guarantees an effective error control of the simulation, independent of the fastest physical time scale for highly unsteady problems. The strategy considers a second-order Strang method and another lower order embedded splitting scheme that takes into account potential loss of order due to the stiffness featured by time-space multi-scale phenomena. The scheme is then built upon a precise numerical analysis of the method and a complementary numerical procedure, conceived to overcome classical restrictions of adaptive time stepping schemes based on lower order embedded methods, whenever asymptotic estimates fail to predict the dynamics of the problem. The performance of the method in terms of control of integration errors is evaluated by numerical simulations of stiff propagating waves coming from nonlinear chemical dynamics models as well as highly multi-scale nanosecond repetitively pulsed gas discharges, which allow to illustrate the method capabilities to consistently describe a broad spectrum of time scales and different physical scenarios for consecutive discharge/post-discharge phases.


Background In an effort to reduce transplantation-related morbidity and mortality in patients (pts) undergoing total body irradiation as part of myeloablative conditioning regimen for hematological malignancies candidated to allogeneic transplant, data have been emerging in support of Helical Tomotherapy to deliver radiation doses to target organs, as bone marrow and lymph nodes, sparing normal organs. We report the first results of feasibility and efficacy of myeloablative Treosulfan-based conditioning chemotherapy combined with dose-escalating (8-10-12 Gy) TMI in pts affected by chemosensitive advanced MM (TrRaMM-TMI: Eudract N° 2013-002479-16). Patients and methods Ten pts (7 females and 3 males with a median age of 60 years), affected by chemosensitive advanced MM have been treated from December 2012 to December 2015. Most of them have received previous therapies with Bortezomib (90%) and IMIDs (80%) and all pts experienced relapse after autologous transplant; active disease was present in the 30% of the pts at the time of the transplant. The pts9 median score of HCT-comorbidity index was 2. All pts received a myeloablative Treosulfan-based chemotherapy (Treosulfan 14g/mq/day on days -6 to -4; Fludarabine 30mg/mq/day on days -6 to-2), combined with TMI delivery on day -2 and -1 if 8Gy and on day -3, -2 and -1 if 10 Gy or 12 Gy, using Helical Tomotherapy. Each pt had a personalized immobilization device and before any fraction the correct set-up was controlled by a mega-voltage CT scan. Three pts have been submitted as pilot cases to TMI 8 Gy, and four and three pts respectively in the two protocol cohorts of TMI 10 Gy and 12 Gy. Peripheral-blood has been the stem cell source for all the pts: three from a matched sibling donor and seven from a matched unrelated donor (10/10 HLA match in six cases and one 9/10 HLA match). A median of 5x10e6 Cd34+/kg and of 319x10e6 Cd3+/Kg have been infused and graft versus host disease (GVHD) prophylaxis with sirolimus and mycophenolate mofetil has been administered; antithymocyte globulin on days -4 to -2 and rituximab on day -1 were added in the unrelated transplant setting. Results All pts received the planned TMI dose in each cohort; engraftment occurred in all pts and no secondary graft failure was observed. No grade 3 and 4 extra-hematological toxicities were observed, and lower grade toxicities, especially gastrointestinal, were completely reversible. No more than 10% of viral reactivations have been demonstrated and one case only of severe sepsis occurred, promptly resolved. No invasive fungal infections occured. No transplant related mortality (TRM) was registered and the two deaths were due to progressive disease. Immune reconstitution after transplant described a T-cell CD8+ and CD4+ repertoire recovery with a median number of 350/microL and of 100/microL on day +90 respectively; NK cells recovery was rapid with a median of 140/microL on day +90, while B cells were still missing on day +90. With a median follow-up time of 22 months on surviving pts, a 2-year PFS of 64% and a 2-year OS of 77% have been described. The day +100 cumulative incidence of grade II-IV acute GVHD was 40%; if grade >III 10%; chronic GVHD 1-year cumulative incidence was 42%; if moderate and severe 31%. 2-year relapse incidence was 36%. Conclusions The first data coming out from the present experience show that TMI addition to Treosulfan-based chemotherapy has not demonstrated an addition of at least short-term toxicities, confirming the combination feasibility, so that TMI 14 Gy delivery is in the plan for the third cohort of the study. Moreover the efficacy outcomes in terms of survival and acceptable TRM, suggest that myeloablative conditioning is feasible in the context of MM and especially promising even in pts with advanced and heavily pretreated disease. Disclosures Bonini: Molmed SpA: Consultancy; TxCell: Membership on an entity9s Board of Directors or advisory committees. Ciceri: MolMed SpA: Consultancy.


Measures that address the seasonality, one of the identified overtourism direct causes, allow making a critical reflection on the application of control policies and monitoring regional measures crucial on a sector with such importance at the regional development analysis. The measures should stimulate or reduce tourism demand during low or peak seasons, respectively, generating a better distribution of tourism flows and eliminating potential overtourism situations. Therefore, this chapter focuses on the development of a Gini Index to analyse the distribution of the seasonality in northern Portugal and through it control current public measures in practice and suggest the implementation of different and more effective policy measures. For instance, the ones that make a clear bet on outdoor tourism activities. It will be used in the Gini Index, by the tourists' market of origin measured by the overnight stays in hotel establishments. The results showed the high seasonal concentration of tourist flows.


Abstract Recent interest in skeletal editing necessitates the continued development of reagent classes with the ability to transfer single atoms. Terminal transition metal nitrides hold immense promise for single‐atom transfer, though their use in organic synthesis has so far been limited. Here we demonstrate a synthetic cycle with associated detailed mechanistic studies that primes the development of terminal transition metal nitrides as valuable single‐atom transfer reagents. Specifically, we show [cis‐terpyOsNCl2]PF6 inserts nitrogen into indenes to afford isoquinolines. Mechanistic studies for each step (insertion, aromatization, product release, and nitride regeneration) are reported, including crystallographic characterization of diverted intermediates, kinetics, and computational studies. The mechanistic foundation set by this synthetic cycle opens the door to the further development of nitrogen insertion heteroarene syntheses promoted by late transition metal nitrides.


According to this study:

* Certain types of meditation, such as mindfulness meditation, may provide health benefits, but additional studies are needed.


Rhumbler's Statement of the Physical hypothesis of Ingestion.

Rhumbler (1914) has stated the physical hypothesis regarding ingestion of foreign particles by cells, not in terms of surface-tension, but in terms of molecular attraction. We shall carry out the necessary transformation of expression (1), which is stated in terms of surface-tension, in order to compare the results with Rhumbler's statement of the conditions.


Given the optimization problem of the assembly line,firstly the basic steps of production line simulation and the two most commonly used optimization techniques—ECRS analysis and operation analysis were illustrated as the theoretical basis. Then,given an assembly line as the research object,the assembly line was modeled,analyzed and that the bottleneck was the steel frame installation process was pointed out based on the FlexSim simulation software. Therefore,an related optimization scheme was proposed by combination of both operation process optimization and station increase point of view, and finally the feasibility and effectiveness of the optimization scheme were verified by the application of FlexSim simulation again. The simulation results showed that,the implementation of the optimization scheme could significantly improve the production efficiency of the target assembly line,and be useful references to the modeling and optimization of the similar manufacturing or logistics systems.


A very remarkable and valuable book, this; the strangeness of its contents renders it one of tho most interesting Egyptological works that have appeared for some years past. Here we have, edited by two of the foremost Egyptian philologists, a collection of extraordinary letters, several of which are now first published, and of which only one had previously boon recognized for what it is. Thanks to Gardiner and Sethe wo now know that it must have been a fairly common custom for tho Egyptians, when in difficulties of a certain kind, to appeal to their deceased relatives for help by means of letters. Tho whole business is beautifully logical. I t often happens that a dead person will, from a grudge that ho bears us, afflict us with sickness or some other disaster; for unfortunately tho dead have wide powers in this direction. To deal with these beings directly is difficult, the magical rituals devised for tho purpose being somewhat unreliable, especially when wo do not know who our ghostly enemy is. Luckily there are efficacious means of dealing with such spirits indirectly. Many tombs bear conspicuous warnings that those who injure or defile them will be prosecuted after their death by the owners of the tombs before " that august Tribunal of tho Underworld." Very well: when we or those dopendent on us are afflicted by malignant dead persons, we will got our departed friends to prosecute them too in the next world, on our behalf. After all, tho dead are tho best people to deal with tho dead, especially since they can identify the enemy when we cannot. This law-court of the Underworld, presided over by the Great God, is a very valuable institution in other ways. On the death of a person who has treated us badly in life, and against whom earthly authorities would not or could not award us our rights, we can turn the matter over to a departed parent or spouse, who will obtain justice for us in that higher tribunal. Again: when it happeus, as it sometimes does, that it is our deceased relative himself who is afflicting us, we can deposit a written complaint against him before the Assize of the West, though this is not such a simple matter.


The Ωt intensity parameters (t=2,4,6) of Er3+ ions in several oxide glasses and the isomer shift (IS) of 151Eu Mossbauer spectra in glasses of the same composition were determined. Among these Ωt's, the Ω6 parameter was found to have a good relation with IS; Ω6 decreases with an increase of IS which reflects the 6s electron density of rare‐earth ions. From the theoretical expression of Ωt, Ω6 is considered to be more affected by the overlap integrals of the 4f and 5d orbitals than Ω2 and Ω4, and to increase with an increase of these overlap integrals. These overlap integrals are supposed to decrease when the 6s electron density is larger, since the 6s electron density shields the 5d electron orbital.


Relative changes in macroscopic iength, DELTA L/L, and x ray lattice parameter, DELTA a/a, of a 99.999% silver bar were measured at 14 to 956 deg C, using a rigid parallel pair of filar micrometer microscopes and a rotating- singlecrystal x ray method. The expansions agree within experimental precision (about 1: 10/sup 5/) at the iower temperatures. At the higher temperatures ( DELTA L/L- deg a/a) progressively increases, showing that atomic sites are added, corresponding to the thermal generation of vacancy-type defects. The concentration of added sites. DELTA N/N = 3( DELTA L/L- DELTA a/a), at the melting point (obtained bya 4 deg extrapolation) is 1.7 plus or minus 0.5 x 10/ sup -4/. This value is only 1/5.5 of the corresponding vaiue found for aluminum by the same technique. For reasonable values of the binding energies of vacancy aggregates, it is concluded that more than 90 percent of these extra sites are present as single vacancies. For an entropy of formation of (1.5 plus or minus 0.5)k an energy of formation for monovacancies of 1.09 = -.10 ev is obtained. This formation energy is sltghtly larger than half the activation energy for self- diffusion. as similar measurements have shownmore » for aluminum and lead, and as quenching experiments have indicated for gold. (auth)« less


Oleocanthal a virgin olive oil phenolic produces varying intensities of irritation in the oropharanx in individuals and is also a naturally occuring NSAID effective in reducing inflammatory markers and increasing protein synthesis in skeletal muscle cells. There may be a link between the variation in throat sensitivity to oleocanthal and its effects on muscle growth processes and inflammation.


The aim of this article is to encourage general dental practitioners (GDPs) to obtain feedback from patients on a regular basis and act on it. This article will familiarize clinicians with the current concepts of patient experience, patient satisfaction and patient reported outcome measures. It will explore the reasons why dentists should engage in seeking patients' opinions and will shed light on some of the validated questionnaires which are in use in the UK and internationally. Aspects of care considered important by patients are explored and important questions which should be included when developing individual practice questionnaires are highlighted. We build on previous Dental Update articles on this subject by taking the reader through the concept of the Plan Do Study Act (PDSA) cycle and how this can be utilized. This paper will not only allow dentists to improve and grow their practices, but also contribute towards clinical governance and the ethos of patient-centred care. CPD/Clinical Relevance: This article enables dental professionals to appreciate the importance of obtaining patient feedback on key issues relating to their dental care. It suggests ways in which dental teams could engage in obtaining patient feedback and act upon it to develop the quality of services.


Introduction: Adequate nutrition is necessary to prevent muscle wasting in critically ill patients. Decision about enteral or parenteral nutrition is always questionable. Objective : The aim of our study was to assess the impact of nutrition on muscle wasting in critically ill patients with trauma injury. Material and m ethods : The study was conducted in the period from January to December 2017 and included 30critically ill patients with trauma injury hospitalized on the Intensive care unit (ICU) of the University clinic for anesthesiology and intensive care in Skopje. Included patients were divided into two groups: g roup E - patients where enteral nutrition was conducted after the third day of their admission in ICU and g roup P - patients where total parenteral nutrition was implemented in the first 24 hours of their admission. The study monitored the impact of two different types of nutrition on muscle wasting evaluated by ultrasound measurements of m.quadriceps femoris thickness and biochemical measurements of the serum creatinine level. Results : In group E there was statistically significant muscle wasting evaluated by ultrasound between the1 st and the 3 rd and the1 st and the 7 th day. Difference in measured muscle thickness was 1.90 ± 1.49 mm between the 1 st and the 3 rd (p = 0.015) and 4.46 ± 2.81 mm between the 1 st and the 7 th day (p = 0.006). In group P muscle wasting in the same period was without statistical significance. Both groups showed statistically significant decrease in serum creatinine levels between the 1 st and the 3 rd (p = 0.003, p = 0.03) and the 1 st and 7 th (p = 0.003) day. The values of differences between the 1 st and the 3 rd and the 1 st and the 7 th  day were 7.57 ± 4.12 mg/dl and 10.71 ± 5.79mg/dl in group E and 11.43 ± 10.66 mg/dl and 15.28 ± 8.28 mg/dl in group P. Conclusion : In our study we determined a significant decrease of muscle mass evaluated by ultrasound measurements of m.quadriceps femoris thickness in patients with enteral nutrition after the third day.


The article is dedicated to the issue of adequacy of financial resources for structural changes in the context of market transformation of Ukraine's economy. It was determined that formal character and uncompleted market reforms in most cases had resulted a strong motivational environment to reduce the domestic development potential and the spread of the shadow economy. The decisive factor in the implementation of the relevant changes was the use of cheap labor, which allowed maintaining a high level of employment, but at the cost of falling efficiency and profitability of production. The GDP cut by almost half but unemployment rate achieved 2%, and not only the labor force but also the enterprises that were privatized depreciated. The funds raised from their sale served as an additional, but very limited, source of public finance.
The objects of privatization were depreciated enterprises, the funds from which served as an additional, but very limited, source to public finance. Their permanent deficit with falling GDP required a stronger tax component to offset rising government spending.
The article presents the consequences of using a deficit model of the economy financing, in particular: falling GDP, including GDP per capita, the formation of a large power of the self-employed population, a significant spread of the shadow economy and the associated large stratification, development of inflationary processes, strengthening of tax pressure on legal business, deteriorating technical and technological condition of enterprises, lack of investment resources in their renewal, a significant amount of non-performing loans, which limits the motivation to invest as well as essential accumulation of debts.
The proposals are made to change the model of economy financing via the transition to domestic sources of expanding effective demand, which stimulates increased productivity through innovation and investment. The implementation of this model involves a consistent increase in the cost of labor, consistent with the reduction of the tax burden, strengthening incentives to reduce costs and increase efficiency and provides expanded investment based on increasing domestic demand.


A semiconductor optical 9mplifier array with 4 channels is presented. This SOA array was coupled to uncoated, flat end, single mode fibers using integrated adiabatic beam expanders, optical index matching gel, and specifically tailored TiO2 anti-reflection coatings. The TiO2 AR coating overcomes the indices misinatching of fiber glass and InP based device, and reduce optical reflection to 0.002% at 1.55 μm. The average coupling loss is 4.3 dB per facet for the devices measured. Fiber coupled small signal gain for the amplifiers is typically 11.6 dB and a saturation output power of 3.0 dBm. The method of characterization and optimization of the TiO2 coating is discussed.


The contract tool, die, and precision machining industry faces unique problems in the area of metrication due to its role as a supplier industry. Although little work to metric specifications is presently being done, and a significant level of awareness exists in the industry regarding the trend toward metrication, only a very small segment of the industry has any definite plans for handling the transition.


The results are discussed of analytical methods designed to predict the crashworthiness of automobile structures. Collapse tests were carried out under torsional moments on square and rectangular section tubes (closed section), a hat section beam closed by spot welding (semi-closed section) and channel beams (open section). Yield and maximum moments in the collapsing process are detailed in respect of cross-section geometry and material properties of the beams. In the case of channels, the effect of constraints against warning deformation of yielding moments was considered using thin-walled beam theory. (Author/TRRL)


The properties of incoherent-feedback random lasing are investigated for dye-doped polymer random media in which non-scattering regions are distributed. Experimental results show that for random media with inhomogeneous structures, the spectral peak intensity increases and the spectral width decreases compared to a homogeneous medium with the same transport mean free path.


Data pipelines for modern complex astronomical instruments do not begin when the data is taken and end when it is delivered to the user. Information must flow between the observatory and the observer from the time a project is conceived and between the observatory and the world well past the time when the original observers have extracted all the information they want from the data. For the 300-fiber Hectospec low dispersion spectrograph on the MMT, the SAO Telescope Data Center is constructing a data pipeline which provides assistance from preparing and submitting observing proposals through observation, reduction, and analysis to publication and an afterlife in the Virtual Observatory. We will describe our semi-automatic pipeline and how it has evolved over the first nine months of operation.


How does trade liberalization that raises a country's import competition affect the innovative activity of its firms? We exploit the strong growth of Chinese exports resulting from China's entry into the World Trade Organization in 2001 as a competitive shock to, specifically, Mexican manufacturing firms. Innovation is captured through information on the adoption of detailed firm level production techniques such as just in time inventory methods, quality control measures, and job rotation among the Mexican firms. Our results indicate that China's rise in global trade did not affect by much Mexico's rate of innovation, which contrasts with the substantial gains that others have found in the case of bilateral liberalizations. At the same time, there is a striking heterogeneity in the responses across firms for different productivities, with productive firms innovating more and less productive firms innovating less, which leads to positive selection in that initial differences in firm performance are sharpened by the advent of new competition. We discuss the implications of these findings for theories of trade and innovation. 1


The solution of the complex economic and meteorological problem of determining the value of thermal resources is suggested. The main principles of evaluating the effectiveness of their use for the objects of socio-economic sphere are formulated.


The complete analytical procedures of metabolomics include sample collection and pretreatment, metabolomic data collection and acquisition, data processing and analysis, as well as markers identification and biological interpretation. In this context, the review deals with the current de- velopment and further trends in the discovery of lung cancer biomarkers based on GC-MS analyti- cal procedures of metabolomics.


Photosynthesis involves light-harvesting complexes where an array of antenna pigment channels the absorbed solar energy to the reaction centre of a photosystem. This work reports a supramolecular dendrimer-dye assembly that mimics the natural light-harvesting mechanism. A dendrimeric molecule based on two-fluorophores has been constructed with three coumarin units at the end of three long arms and a 7-diethylaminocoumarin unit at the interior. The molecule self-aggregates in water into spherical micelles, which can encapsulate a rose-bengal dye (RB). On excitation, peripheral coumarin units shuttled the energy to the loaded RB dye reaction center via a two-step cascade resonance energy transfer (RET). The energy absorbed in the periphery is funneled efficiently, resulting in a strong emission from the dye that resembles an energy funnel. The energy transfer cascade has been studied with both steady-state and time-resolved fluorescence spectroscopy. Molecular dynamics simulations of the self-assembled aggregates in water were also in agreement with the experimental observations.


A monitoring system is needed in order for DDS middleware to become more widely used in warfare, finance, and traffic control systems. Here, we propose a programming pattern that functions as a full-duplex listening structure, and apply it to implement tools for DDS monitoring and analysis. The full-duplex listening structure allows each of the multiple modules to independently perceive events, and then determine appropriate behavior for each event. Because this structure implements event-generating and event-consuming processes in parallel, it reduces development time and cost.


Dear Editor, On March 11, 2020, the World Health Organization (WHO) characterized the coronavirus disease 2019 (COVID-19), which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as a pandemic.(1) The novel coronavirus disease has originated as a cluster of unexplained cases of pneumonia in Wuhan, China, and it has scaled to new heights of mortality by affecting people both physically and mentally. The context of unpredictability and uncertainty associated with the lockdown, the numerous restrictions, unemployment, and changes in the standard of living, have limited the already precarious access to mental health services. In addition, these issues have been imposed a great psychological burden on the population. Consequently, an increase in the prevalence of mental disorders in previously healthy individuals were observed, as well as the aggravation of pre-existing mental disorders.(2) In the general public, there was an increase in the incidence of depression, anxiety, stress, panic disorder, obsessive-compulsive disorder, somatic symptoms, sleep disorders, delirium, psychosis, self-mutilation, and suicide. In addition to the factors already mentioned, insecurity about the future, fear of contracting the disease, fear of the negative economic effects due to the pandemic, the lack of information and scientifically proven treatment are some of the factors responsible for these mental issues. The spread of false information, the scarcity of essential products, and fear also led to an increase in panic buying episodes. People with pre-existing mental disorders reported worsening symptoms, relapse, and suicidal behaviour due to the interruption of psychiatric care, home confinement, and changes in their daily routine. In addition, restrictive measures have reduced patients' access to family and social support networks.(2) In a study conducted in China, home confinement and centralized quarantine were found to be associated significantly with increased risk of psychological outcomes including anxiety, depression, insomnia, and acute stress.(3) Furthermore, the lockdown measures have restricted people to their homes and infringed upon their freedom. This has resulted in various deleterious ways of coping with daily stressors, such as alcohol, drug and tobacco abuse, potentially addictive behaviours, such as online gaming and gambling, and rise in rates of domestic violence and sexual abuse.(4) How to cite this article: Costa AC, Menon V, Phadke R, Dapke K, Miranda AV, Ahmad S, et al. Mental health in the post COVID-19 era: future perspectives [letter]. einstein (São Paulo). 2022;20:eCE6760.


Chlorinated ethenes are known or suspected carcinogens. They are also among the most frequently detected organic groundwater contaminants because of wide use and poor disposal practices. Within anaerobic aquifer systems, Fe(III) reduction is a prevalent terminal electron accepting process and has often been reported as a competitive electron acceptor with respect to trichloroethene (TCE), cis-dichloroethene (cis-DCE), and vinyl chloride (VC) reduction. Often, practitioners add excessive amounts of electron donor to compensate for this competition in an effort to avoid incomplete dechlorination or "cis-DCE and VC stall." Contaminated aquifer material incubations were setup to assess dechlorination rates and extent under Fe(III)-reducing conditions, and to evaluate whether excessive electron donor additions increase either the rate or extent of complete dechlorination of TCE or VC using acetate and vegetable oil-based electron donors. Sediment batch experiments were constructed to specifically assess how Fe(III) speciation and the presence of electron shuttles influenced VC dechlorination. Four treatments were investigated: (1) VC +10 mM ferrihydrite; (2) VC + 10 mM Fe(III)-NTA; (3) VC + 10 mM ferrihydrite + 500 μM AQDS; and (4) VC + 5 mM AQDS. Sediment batch experiments were also set up to specifically evaluate how electron donor concentration affected TCE and VC reduction using acetate and vegetable oils (Newman Zone® Standard without


Abstract Introduction Vasospasm is a common and potentially devastating complication in patients with subarachnoid hemorrhage, causing high morbidity and mortality. There is no effective and consistent way to prevent or treat cerebral vasospasm capable of altering the morbidity and mortality of this complication. Animal and human studies have attempted to show improvement in aneurysmal vasospasm. Some sought their prevention; others, the treatment of already installed vasospasm. Some achieved only angiographic improvement without clinical correlation, others achieved both, but with ephemeral duration or at the expense of very harmful associated effects. Endovascular techniques allow immediate and aggressive treatment of cerebral vasospasm and include methods such as mechanical and chemical angioplasty. These methods have risks and benefits. Objectives To analyze the results of chemical angioplasty using nitroglycerin (GTN). In addition, to perform a comprehensive review and analysis of aneurysmal vasospasm. Methods We describe our series of 77 patients treated for 8 years with angioplasty for vasospasm, either mechanical (with balloon), chemical (with GTN) or both. Results Eleven patients received only balloon; 37 received only GTN; 29 received both. Forty-four patients (70.1%) evolved with delayed cerebral ischemia and 19 died (mortality of 24.7%). Two deaths were causally related to the rupture of the vessel by the balloon. The only predictors of poor outcome were the need for external ventricular drainage in the first hours of admission, and isolated mechanical angioplasty. Conclusions Balloon angioplasty has excellent results, but it is restricted to proximal vessels and is not without complications. Chemical angioplasty using nitroglycerin has reasonable but short-lived results and further research is needed about it. It is restricted to vasospasm angioplasties only in hospitals, like ours, where better and more potent vasodilator agents are not available.


In the story-adding transformation design of a six-story steel frame by added-story of light-weight portal frame for the increased functional requirements,it is found out that the foundation and original structure can be used and meet the design specification requirements without strengthening.This paper nalyzes the static and dynamic characteristics of its upper main structure by the software ETABS,explores the bearing capacity,deformation under static load before and after story-adding transformation and the changes of natural frequency,vibration mode,inter-story drift angle,acceleration and the failure mode of the structures under earthquake.By added support it is possible to improve the structural stiffness distribution and dynamic characteristics,reduce the seismic action,make it meet the design specifications.The paper provides a reference to similar story-adding transformation project.


In this work we discover that a specific recognition of the N‐terminal lectin domain of FimH adhesin by the usher FimD is essential for the biogenesis of type 1 pili in Escherichia coli. These filamentous organelles are assembled by the chaperone–usher pathway, in which binary complexes between fimbrial subunits and the periplasmic chaperone FimC are recognized by the outer membrane protein FimD (the usher). FimH adhesin initiates fimbriae polymerization and is the first subunit incorporated in the filament. Accordingly, FimD shows higher affinity for the FimC/FimH complex although the structural basis of this specificity is unknown. We have analysed the assembly into fimbria, and the interaction with FimD in vivo, of FimH variants in which the N‐terminal lectin domain of FimH was deleted or substituted by different immunoglobulin (Ig) domains, or in which these Ig domains were fused to the N‐terminus of full‐length FimH. From these data, along with the analysis of a FimH mutant with a single amino acid change (G16D) in the N‐terminal lectin domain, we conclude that the lectin domain of FimH is recognized by FimD usher as an essential step for type 1 pilus biogenesis.


The Pediatric Oncology in Developing Countries (PODC) committee of the International Society of Pediatric Oncology (SIOP) published a pediatric acute myeloid leukemia (AML)‐specific adapted treatment guideline for low‐ and middle‐income countries. We evaluated the outcomes of children with AML at a large Kenyan academic hospital before (period 1) and after (period 2) implementing this guideline.


A non-invasive and accurate modality that can continuously monitor stroke volume (SV) for extended periods of time is desired to allow for more proactive care of an increasing population of patients living with heart failure. Electrical impedance tomography (EIT) has been proposed as a method for accurate, non-invasive, continuous, and long-term SV monitoring. While cardiac EIT has been explored, clinical translation has yet to occur and a standardized method for evaluation and comparison of cardiac EIT images is desired. This work explores an automated process for segmenting and extracting features from the images that allow for evaluation and comparison. A simulation study was conducted using the 4D XCAT model to evaluate the proposed method's ability to automatically segment and extract features from images reconstructed at various phases of the cardiac cycle. The same procedure was then applied to EIT reconstructions on data collected from five healthy volunteers. The automated segmentation is able to accurately capture the heart region-of-interest (ROI) in various images and extract features, which allows comparison of desired signals across reconstructions. ROI mean conductivity, ROI area, sum of conductivities within the ROI, and ROI maximum conductivity were chosen as promising features from the simulation study, with R2 values of 0.61, 0.73, 0.75, and 0.66 for a single heart-cycle, and minimum SV distinguishability of 25.54, 12.16, 12.16, and 17.22 ml. In experimental data, the area feature showed the least variation across individual reconstructions while the sum feature showed the highest variation.


The concept of a Shear Transformation Zone (STZ) refers to a region in an amorphous solid that undergoes a plastic event when the material is put under an external mechanical load. An important question that had accompanied the development of the theory of plasticity in amorphous solids for many years now is whether an STZ is a region existing in the material (which can be predicted by analyzing the unloaded material), or it is an event that depends on the loading protocol (i.e., the event cannot be predicted without following the protocol itself). In this letter we present strong evidence that the latter is the case. Infinitesimal changes of protocol result in macroscopically big jumps in the positions of plastic events, meaning that these can never be predicted from considering the unloaded material.


Medicinal use of spices/herbs has been gradually increased in the developed countries, Zingiber officinale (Ginger) is known to possess potent antioxidant and anti inflammatory properties. Therefore, the aim of this study is to determine the possible anti-mutagenic effect of ginger against the genotoxic effect of anti-cancer drug Taxol 0.6 mg/kg. This study is conducted by using two types of cytogenetic studies in bone marrow cell of mal albino mice Mus musculus (average weight 25-30 g). The animals were randomly distributed into six groups, each of 14 mice, (G1) was given the solvent, (G2) treatment of the medical dose of Taxol drug, (G3) treatment of ginger, (G4) a pre-treatment of ginger prior to treatment of drug, (G5) a simultaneous treatment of ginger and treatment of drug, (G6) a post-treatment of ginger after treatment drug. The study results show that significant increase in total chromosomal aberrations and significant increase in the number of micronuclei were observed after treatment drug. The significant structural aberrations were in the form of end-to-end associations. The numerical chromosomal aberrations were endomitosis and polyploid. The results showed that the frequencies of chromosomal aberrations and micronuclei in ginger treated group were not significantly different from control. Simultaneous treatment of ginger was found to be effective in reducing the genotoxic effects induced by drug Taxol especially in the total number of the chromosomal aberrations and the number of micronuclei.


Purpose: This study aimed to evaluate the effect of calcium dobesilate uptake on visual acuity (VA) and macular thickness by optical coherence tomography (OCT) of eyes with non-proliferative diabetic retinopathy (NPDR) in comparison with bilberry dried extract. Methods: Thirty-six eyes of 36 patients diagnosed with NPDR without macular edema and who were treated with calcium dobesilate for more than 6 months were enrolled in the calcium dobesilate (CAD) group. VA, diabetic retinopathy grade, central macular thickness (CMT), and total macular volume (TMV) at baseline and at the 3and 6-month follow-up examinations were analyzed retrospectively. The matched patients treated with bilberry dried extract were selected and compared as the control group. Results: The CMT and TMV values were 282.14 ± 31.86, 277.96 ± 31.13, and 281.18 ± 30.41 μm and 8.79 ± 0.58, 8.68 ± 0.59, and 8.73 ± 0.60 mm in the CAD group at baseline and at the 3and 6-month follow-up, respectively. The TMV had decreased significantly at the 3-month follow-up (p = 0.027); however, the TMV at the 6-month follow-up and the VA and TMV at the 3and 6-month follow-ups showed no differences from the baseline levels (all p > 0.05). In the control group, no significant changes in VA or in CMT were observed at 3 and 6 months after treatment compared to the baseline (all p > 0.05). Furthermore, no significant difference in CMT on OCT was observed between the two groups at all time points (all p > 0.05). Conclusions: In NPDR patients without macular edema, CAD uptake had no significant effect on VA or macular thickness until 6 months after treatment. Ann Optom Contact Lens 2021;20(2):62-66


In order to obtain information regarding given phenomenon or object, it is usually necessary to register selected measurement signals obtained using sensors. Unfortunately, obtained signals, apart form desired information, contain disturbances caused by, amongst many other, properties of the measurement channel and processes associated with object operation. In many cases it is necessary to measure the same value in different places and/or directions. Thus, there is a demand for a tool improving signal to noise ration of the multi-channel registered signals.Wavelet transform is a relatively new method of data processing used in different fields (e.g. technique and physics). In case of signals it can be used for denoising, compression, trend detection or discontinuity detection. In this work it was used to denoise vibration signals registered by two three-axis sensors. Object of investigation was the bevel toothed gear. Signals denoising was to improve efficiency of the diagnosis of transmission gears teeth damage.


In this report of the study of teaching community dentistry in the United States, Dr. Petterson investigates the curricula available in 23 departments, the resources for teaching, and the activities developed by the faculties.


THERE is an increasing appreciation of ecology as a fundamental construct in the study of human problems. In a review of relevant experimental literature, Hunt 1 has concluded that the major variation in behavior is not due to "... individual differences in subjects per se, nor the variations among situations per se. It is, rather, the interactions among these which are important." From the context of the emerging field of community mental health, Kelly, 2 Klein, 3 and Kalis 4 have emphasized the relevance of ecological considerations for community psychology. This recognition of the "mutuality" between persons and their environments has slowly become explicit in research design. 5,6 Nowhere are human-community problems more acute than in the heavily populated metropolitan centers. 7 Two examples of widespread urban problems are suicide and alcoholism. The present communication represents a preliminary attempt to assess whether these two problems are interrelated and, if so, in


In this paper, multiband Bow Tie antenna with the circular arm is proposed with two circular slots of radius 13 mm in the ground plane. By applying the Apollonian Gasket of fractal geometry on the circular arm of Bow Tie this antenna is resonating at four frequencies, 3.57, 5.79, 6.99 and 8.38 GHz with reflection coefficient values of -19.42 dB, -52.97 dB, -29.93 dB and -26.92 dB respectively. With a circular slot reflection coefficient <; -10 dB in whole UWB range (3.1-10.6 GHz) is obtained except for a band rejection between 8.85-9.96 GHz. The radiation pattern is almost omnidirectional for UWB. The maximum gain obtained is 5.89 dBi. This designed antenna is 94.8% efficient for above four resonating frequencies and efficiency is more than 45% of whole UWB range. By inserting circular slots in the ground plane of proposed antenna the various parameters have been improved such as return loss, bandwidth and gain. Simulation has done up to 3rd iteration of the fractal. Designing and simulation of this antenna have been done with the help of IE3D 15.3 software. The application of this antenna is in satellite, cellular mobile and radar.


ABSTRACT First-principles computations of the structural, electronic, optical and mechanical properties of LaRu2P2 compound are reported. The optimised lattice parameters match well with a previous study, which shows the authenticity of our calculations. The electronic properties indicate the metallic nature of material. At the Fermi level, the overlapping of conduction and valence band represents the metallic nature of the compound. The Mulliken population analysis is used to investigate the bonding nature in the compound. The optical properties indicate that in the low-energy region, LaRu2P2 has a strong absorption coefficient and a high refractive index. The mechanical stability is determined with the help of Born stability criteria and the compound is found mechanically stable. The ductile behaviour of the material was confirmed by Pugh's and Poisson's ratios. The mechanical properties show that the material is anisotropic in nature. Due to the superconducting nature of the compound, it may be utilised for superconducting applications.


Abstract. The success of prosthetics in patients using fixed orthopedic structures on vital teeth is determined both by the high-quality preparation of teeth and by the antibacterial effect on the dentinal tubules exposed after preparation in order to reduce paresthesia and prevent bacteria from penetrating them.
Orthopedic dentists are wary of certain potential problems that may arise when working with vital teeth. In this regard, the doctor should take care of the prevention of possible complications that arise after prosthetics with non-removable orthopedic structures, since the tooth after preparation has an unprotected dentin surface. During the preparation, a certain volume of hard tissues of the tooth is removed, which in functional terms is the integumentary tissue, and then comes the exposed peripheral dentin.
Such an impact of various factors on the vital tooth can lead to damage to the dental pulp.
This article discusses various ways to prevent tooth pulpitis, which can occur during tooth prosthetics with non-removable orthopedic structures due to the influence of physical and mechanical factors on the hard tissues of the tooth, or rather, due to the friction of the diamond bur against the hard tissues of the tooth during odontopreparation, as well as the penetration of bacteria along exposed dentinal tubules into the dental pulp.
The purpose is to study and analyze data on various cements for temporary fixation of fixed orthopedic structures used to prevent pulpitis of vital abutment teeth. To analyze and identify what other modifications of temporary and permanent fixing cements for non-removable orthopedic structures are relevant to use in modern dentistry for prosthetics on vital teeth.


In this paper, a new feature of surface electromyo-graphy (sEMG) by using discrete wavelet transform (DWT) is proposed for motion recognition of upper limbs, and this method can be eventually used for rehabilitation robot control. Seven traditional features of sEMG are also extracted for comparative study, they are integral of absolute value (IAV), difference absolute mean value (DAMV), zero crossing (ZC), variance (VAR), mean power spectral density (MPSD), mean frequency (MF) and median frequency (MDF) respectively. For comparing the recognition rate of the different motions of the upper limb, each feature or their combination are used to construct the feature vectors, and the BP neural network with variable learning rate back propagation with momentum (GDX) algorithm is used to classify these motion modes. The experimental results summarize that the new feature extracted by using DWT presents a higher recognition rate (98.9%) than all of the traditional features, and the traditional features combination can also greatly improve the recognition rate (99%).


The aim of the paper is to develop knowledge about preschool teacher's professional development in activities based on a play pedagogical approach known as playworlds (Lindqvist, 1995). There is sc ...


This study aims to determine the effect of competence, compensation for organizational citizenship behavior (OCB) and job performance in life insurance companies in Batam City. The sample of this study was 244 respondents with the proportionate sampling method and purposive sampling was designed. Data were collected using a questionnaire with a Likert scale and then analyzed with Structural Equation Modeling (SEM) through the AMOS program version 21. The results of the analysis proved that Competence had a significant effect on Compensation; Compensation has a significant effect on Organizational Citizenship Behavior (OCB); Competence has a significant effect on Organizational Citizenship Behavior (OCB); Compensation has a significant effect on Job Performance; Organizational Citizenship Behavior (OCB) has a significant effect on Job Performance; Competence has a significant effect on Job Performance of life insurance in Batam City.


Plasma simulations are often rendered challenging by the disparity of scales in time and in space which must be resolved. When these disparities are in distinctive zones of the simulation region, a method which has proven to be e(cid:11)ective in other areas (e.g. (cid:13)uid dynamics simulations) is the mesh re(cid:12)nement technique. We brie(cid:13)y discuss the challenges posed by coupling this technique with plasma Particle-In-Cell simulations and present two implementations in more detail, with examples.


Objective:To investigate the therapeutic effect of acute lumbar sprain with treatment of acupuncture and massage plus specific electromagnetic spectrum treatment radiator(TDP).Methods:Sixty-three cases of acute lumbar sprain clinical data were analyzed retrospectively.Results:Forty-three patients were cured,11 cases was markedly effective,6 cases was effective and 3 cases was noneffective.Conclusion:Most patients treated by acupuncture and massage plus TDP achieve satisfactory results.By acupuncture plus TDP clinical treatment of acute lumbar sprain massage can not only shorten the course of treatment,but also improve the efficacy.


The low temperature oxidation resistance of MoSi2 and MoSi2-AlCr2 quasibinary system alloys at 500 ℃ was investigated by TGA,XRD and SEM.The results show that MoSi2 and MoSi2-AlCr2 quasibinary system alloys which are prepared by hot-pressed sintering have excellent low temperature oxidation resistance under 500 ℃ cyclic oxidation condition."Pesting" phenomena are not found in the pure MoSi2 and MoSi2-AlCr2 quasibinary system alloys after oxidation for 100 h.The oxidation kinetics curve of the pure MoSi2 is followed parabolic law while the MoSi2-AlCr2 quasibinary system alloys are followed the straight-line law at the stage of 20 h-100 h.The low temperature oxidation resistance of MoSi2 is dramatically improved when added AlCr2.


I study self-learning pricing algorithms and show that they are collusive in market simulations. To derive a counterfactual that resembles traditional tacit collusion, I conduct market experiments with humans in the same environment. Across different treatments, I vary the market size and the number of firms that use a pricing algorithm. I demonstrate that oligopoly markets become more collusive if algorithms make pricing decisions instead of humans. In two-firm markets, prices are weakly increasing in the number of algorithms in the market. In three-firm markets, algorithms weaken competition if most firms use an algorithm and human sellers are inexperienced.


Understanding the application of a bipolar Junction transistor or BJT as a switch requiers understanding the general working principles behind a transistor and the specific working principles behind a BJT. A transistor is essentially a semiconductor device with physical properties that make it ideal for amplifying or switching electric current and other signal. At the heart of this device is a doped semiconductor with engineered properties to alter its conductivity for a particular use. A BJT is a type of transistor with two major semiconductor materials that constitute three major areas or regions, each doped according to requirements. This architectural characteristics of a BJT brings forth effective applications in implications or on-off switching operations. Nonetheless, understanding BJT as a switch requires understanding the working principles underneath the device, the functions of each of the three major regions within this transistor, and the role of electron movement or current flow in the switching mechanism


We reported a case of 17-year-old man of clear cell sarcoma. Two years ago, he noticed a slowly progressive subcutaneous tumor of thumb. Aspiration biopsy was done and diagnosed giant cell tumor of tendon sheath.We operated and histologically revealed clear cell sarcoma of tendons and aponeuroses. The tumor was positive for S-100 protein staining. In electron microscopy, melanosome was found in tumor cells. After 8 months following up, lung metastasis was found and after that brain metastasis was found


Gestation is a stressful state that involved physiological change. Environmental stressor could alter the adaptive mechanism during gestation, thus bring bad impact to the developing fetus. Music is commonly used as a therapy media to minimize stress during gestation. This research aims to examine the effect of listening murottal and rock music during gestation towards levels of oxidative stress in mouse dams (Mus musculus) and the morphological structure of the fetuses. The levels of oxidative stress were analyzed by measuring malondialdehyde (MDA) level as the biomarker. This research was conducted from July to November 2016 in Zoology Laboratory and Chemical Laboratory of Faculty of Mathematics and Natural Sciences Tanjungpura University Pontianak. Fifteen mice were divided into 2 experimental groups (murottal/M and rock/R) and 1 control group (K). During day 0 to day 15 of gestation, the pregnant mouse dams in group M and R were exposed to murottal and rock music, respectively. Laparatomy was conducted on the 16th day of gestation, followed by serum MDA measurements and observing the fetuses. According to the result, MDA level in group M was significantly lower (0.42±0.21 nmol/mL; p<0.05) than two other groups. This result accompanied by the normal fetuses with highest mean of weight (0.74±0.05 g) and length (18.72±0.90 mm) compared to fetuses from group R and K. Fetus with hemorrhage and intrauterine growth restriction (IUGR) were found in group R, while intrauterine mortality was found in group R and K.


The racemic mixture of naproxen was prepared from β-naphtholby methylation,acylation,bromination,acetalization,esterification and rearran-gement.1-(6-methoxy-2-naphthyl)-2-hydroxypropan-1-one dimethyl acetal wasesterified with benzenesulphonyl chloride or tosyl chloride,then the products wererearranged to naproxen,the overall yield was respectively 50% and 41%.


Based on the analysis of fuze turbine alternator speed control mechanism schemes at home and abroad,a turbine alternator adjustable nozzle mechanism scheme using the new material of shape memory alloy(SMA) was brought forward to fulfill the control of turbine alternator speed under altering airstream condition.As the aerodynamic heat temperature of the entry pipe wall varies with the flow speed change,the sensitivity to temperature of SMA is used to adjust the exit area of the entry pipe,then control the flow momentum into the turbine alternator,so that the turbine alternator speed is under control.The research result also could be applied in the adapting adjustment of the rocket engine nozzle to fulfill the engine thrust adjustment.


The author discusses the advent of quality management systems, their rapid growth in popularity, and their benefits to service industries such as electricity utilities. The meaning of quality in this context is defined, and the essential elements of quality management systems are listed. A brief discussion of a typical quality management system is presented. This discussion is based on the author's experience in assisting the electricity department of a local authority with implementing an ISO 9000 based quality management system.


The present invention provides an aligning mark which is used for the aligning system of the photo-etching device and a using method thereof. The aligning mark comprising at least three groups of raster with different periods is used. The +/-1 grade diffraction lights of three groups of raster are used in the aligning process. Two large-period raster in three groups of raster are used for coarse alignment. A small-period raster is used for refined alignment. The alignment position error caused by the asymmetrical deformation of the aligning mark is reduced. The small period raster and the large period raster are spatially staggered. The corresponding interface images are spatially divided in the image surface. The crosstalk problem of signal is effectively settled. The energy usage of light source is increased. The intensity of aligning signal and the dynamic range of detection are facilitated to increase.


A new testability solution is proposed in which externally accessible test points are pre-designed into cells that comprise the VLSI designs. The test points are accessed through an on-chip grid of orthogonal probe and sense lines. The resultant VLSI design consists of a large number of test points through which test signals on every cell on the IC can be measured or modified to a limited extent. The sizable number of test points improves the testability of the designs by a very large factor. Additionally, analog measurement and signal injection capabilities allow detection of practical CMOS fault modes such as opens, shorts, open or closed FETs and even noise margins. The large observability of CrossCheck based designs reduces the automatic test pattern generation problem to one of providing control only. Several ISCAS benchmark designs are analyzed using CrossCheck cell libraries and fault models. The results show that over 97 percent coverage of a broad range of fault modes, such as opens and shorts, can be obtained on VLSI CMOS designs without the need for large computing resources.


Development of a new generation of Bridge Management System (BMS) capabilities has been a high priority for CALTRANS for the past four years. Although the Department has had a bridge inventory system, with a very extensive suite of management reports, since the late 1970s, CALTRANS has recognized that selected newly-available technologies could be integrated into its management decision-making, planning, and operations to substantially enhance its effectiveness in managing a 24,000-bridge inventory. One of the key components of CALTRANS' BMS is Pontis, a network-level optimization system which analyzes bridge deterioration, costs, and functional needs to plot a long-term bridge management strategy, and recommend a short-term program of projects consistent with that strategy and funding availability. To complement the network level analysis provided by Pontis, CALTRANS is implementing a computerized image storage and retrieval system named BWS to aid an engineer in project level analysis by providing quick and easy access to bridge inspection records and as-built construction plans.


A Case of Multisaccular Thoracic Aortic Aneurysm Associated with Coarctation of the Aorta Shinya Yokoyama, Yuji Naito, Eisei Koh, and Hiroshi Katayama* (Department of Cardiovascular Surgery, Kyoto Second Red Cross Hospital, Kyoto, Japan and Department of Pediatrics, Osaka Medical College*, Osaka, Japan) A 9-year-old boy with multisaccular thoracic aortic aneurysm associated with coarctation of the aorta underwent definitive repair under partial cardiopulmonary bypass. The operation consisted of resection of the aneurysm and reconstruction of the descending aorta. Aortic reconstruction was done without an artificial graft, and extended end-to-end anastomosis was performed successfully. He has been doing well and there was no significant restenosis at the repair site 5 years after the operation. Some authors reported that untreated coarctation of the aorta frequently developed aneerysm, which usually has multisaccular lesions. Surgical strategy of aortic reconstruction for coarctation of the aorta in boyhood should be decided prudently to avoid postoperative complications. Jpn. J. Cardiovasc. Surg. 34: 370-373 (2005)


The Jurassic/Triassic Age Nugget sandstone of the southwestern Wyoming overthrust belt is a texturally heterogeneous reservoir with anisotropic properties that have been inherited primarily from the depositional environment but also have been modified by diagenesis and overprinted by tectonism. Predominantly Eolian processes deposited crossbedded, low-angle to horizontally bedded and rippled, very-fine- to coarse-grained sand in dunes, interdune areas, and associated environments. Original reservoir quality has been somewhat modified by compaction, cementation, dissolution, clay mineralization, and the precipitation or emplacement of hydrocarbon asphaltenes or residues. Low-permeability gouge- and carbonate-filled fractures potentially restrict hydrocarbon distribution and negatively affect producibility, whereas discontinuous open fractures enhance permeability in some intervals. Contrast in air permeability between dune and interdune deposits ranges over four to five orders of magnitude. Dune and interdune intervals are correlatable locally with the aid of core log, conventional log, and stratigraphic dipmeter data. Stratigraphic correlations then can be utilized to model the lateral and vertical extent of directional properties in the reservoir.


CORRESPONDÊNCIA. Esta seção de Arquivos de neuro-psiquiatria divulga opiniões e observações construtivas acerca de artigos publicados em seus últimos números. São aceitas cartas assinadas, sucintas e desprovidas de caráter pessoal, abordando aspectos objetivos dos artigos e utilizando até cinco referências bibliográficas. Enviar sua contribuição em uma via acompanhada do respectivo disquete. Utilizar o endereço: Arquivos de Neuro-Psiquiatria, Praça Amadeu Amaral 47 / 33, 01327-010 São Paulo SP ou E-mail: firstname.lastname@example.com To The ediTor The year 2009 is the 150 Anniversary of the publication of On the Origin of Species (24 November 1859) and the 200 Anniversary of Darwin's birth. Charles Robert Darwin was born on February 12, 1809 in Shrewsbury, England. From 1831 to 1836, Darwin served as naturalist aboard the H.M.S. Beagle on a British science expedition around the world. In South America, Darwin found fossils of extinct animals that were similar to modern species. On the Galapagos Islands in the Pacific Ocean he noticed many variations among plants and animals of the same general type as those in South America. The expedition visited places around the world, and Darwin studied plants and animals everywhere he went, collecting specimens for further study. Out of this tudy, Darwin formulated several theories. He set forth these theories in his book called, On the Origin of Species by Means of Natural Selection, or the Preservation of Favoured Races in the Struggle for Life (1859) or "The Origin of Species" for short. After publication of Origin of Species, Darwin continued to write on botany, geology, and zoology until his death in 1882. He is buried in Westminster Abbey. In 1832, Darwin arrived in Brazil, where he stayed for four months, particularly in Rio de Janeiro and Salvador/Bahia. Later, The Origin of Species, called the attention of a German descendant physician, Fritz Mueller, a naturalist, who lived in Blumenau and Florianopolis, Santa Catarina. There he studied Crustacea species and his studies resulted in a supporting book to Darwin's theories entitled "Für Darwin", later translated in English as "Facts and Arguments for Darwin". He and Darwin kept correspondence until Darwin's death in 1882. Several historical studies and biographical essays have tried to correlate his illnes during his lifetime, described by himself, with several possible diseases. Among them, anxiety, panic disorder with agoraphobia, hypocondria, arsenic poisoning, chronic allergy, Crohn's disease, lactose intolerance and Chagas' disease have been postulated. The hypothesis of Chagas' disease is quite exciting and is based on two points. First, Darwin mentioned in his autobiography that he was bitten by several Benchucas, a insect species Reduvius, a great black bud of the Pampas, on March 25, 1835, in the small village Luján, Mendonza province, Argentina. There is a general consensus that Benchucas were in fact Triatoma infestans, the insect carrier of Trypanosoma cruzi, described by the Brazilian scientist Carlos Chagas, in 1909. A second supporting factor is the set of symptoms refered by Darwin himself, during his chronic illness, including digestive complaints (vomiting attacks, eructation, flatulence) and particularly the pre-syncopal and syncopal episodes, more frequent at the end of his life, associated with complaints of effort dyspnea and palpitations, in keeping with a cardiomyopathy leading to cardiac syncopal episodes (described as occurring in supine position). Nevertheless, the possibility of Chagas' disease acquired by Darwin during his passage in South America is still discussed, as well as even nowadays his genial theory of evolution, in special among some groups of religious theorists.


Executive Summary it has long been understood that health outcomes are profoundly shaped not just by biological factors but also by the social, economic and cultural environment, including people's positions in various social hierarchies. increasing evidence suggests that it is possible to improve health outcomes through action on these social determinants of health. Still, consensus on priority actions and investments to address these social determinants remains elusive. this document contributes to the ongoing debate by considering maternal health and asking what has and can be done to improve maternal health outcomes through action on social determinants. maternal mortality is a key indicator for maternal health and reveals dramatic inequalities between and within countries that cannot be attributed to biological differences. reducing maternal mortality relies on preventing unintended pregnancy through family planning and reproductive health. Skilled attendance at birth and emergency referrals are also required to reduce both maternal complications and resulting deaths. the characteristics of individual women like age, number of previous pregnancies, and education level play a role in determining whether they seek appropriate services, but the underlying factors influencing health behavior operate at interrelated levels of social influence: family and peers, the community in which women live and the health system available to them, wider cultural norms, the legal and policy environment and overarching governance structures. Addressing each of these levels is necessary for a comprehensive social determinants approach to maternal health. Some existing interventions already target social determinants and provide evidence of impact. peer counseling provides social support to individual women while cash transfers or participatory women's groups help address economic marginalization and build social capital at community level. legal reforms can protect women from discrimination while policy changes can address harmful gender norms and expand women's and girls' access to education and economic independence. many of these approaches occur outside the health sector, but provide complementary support to health systems approaches that work to increase coverage, reduce costs, and improve service access and quality. the multiplicity of actors both within and outside the health system presents coordination challenges; yet, coordination is paramount to ensuring an effective response to maternal health. lessons from several decades of hiV programs can show how seemingly disparate interventions can be brought together into a cohesive multi-sectoral response. there is significant expertise in implementing structural interventions to reduce hiV vulnerability, the principles of which can be applied to maternal health. promoting democratic …


Novel RF and IF amplifiers worldwide are described, together with their performances and technology characteristics.The latest development of low-noise wideband amplifiers, operational amplifiers and comparators, intermediate or video amplifiers, and analog multipliers and their applications in electronic systems are elaborated.


Metal−organic frameworks (MOFs) are novel microporous materials with large surface areas, porosities, and thermal stabilities. Even though many thousand MOFs have been identified, few MOF materials have been evaluated for gas mixtures separations and fuel gas storage. In this work, using grand canonical Monte Carlo simulations, we calculated adsorption isotherms of pure and binary mixtures of hydrogen−methane in two large surface area MOFs (MOF-5 and MOF-177), two catenated MOFs (IRMOF-11 and MOF-14), and a high affinity open metal site MOF with strong Znδ+−Oδ− dipoles on the surface that create strong energetic interaction with the adsorbates (MOF-74). The pure and mixture adsorption isotherms were calculated at 298 K and up to pressures of approximately 80 bar. The results of this study indicate that separation of hydrogen from methane in these materials would be successful, since hydrogen in a 50% bulk mixture at low pressures has selectivities on the order of 25 for MOF-74, 20 for IRMOF-11, and 18 for...


Engineering materials are classified into many varies and composites are those which are finding their role in all modern day engineering applications. Composite materials are materials made of two basic components, polymer resins and fibers. It combines the physical properties and high mechanical properties of the fiber, as well as the appearance, adhesion and performance of the polymer. Here, we prefer brown grass flower brooms as our main fiber to form composite materials. Brown grass is scientifically called Thysanolaena maxima, which comes from the family Poaceae and commonly known as kucho/amlisho, in southern Bhutanese language.


Computerized thermography, system with ability to capture the infrared light emissivity of any reflexive surface, is part of the current arsenal of instrumentation in biomechanics. Using this methodology, it is possible to evaluate the physiology of thermical maintenance through its skin surface representation. The aim of this work is to evaluate the thermography as the identification method of myofascial trigger points, been chosen the trapezius muscle as study focus since it is one of most affected body regions concerning myofascial syndrome. This syndrome is highly prevalent and historically sub-diagnosticated as it requires expert professionals to establish its diagnostic, through physical examination. The articipants of this study were gathered as a sample of thirty persons, fifteen men and fifteen woman, ages between twenty three and seventy years (32,5 years in average). The algometry by pressure, highly validated method on previous works, has been used as part of physical examination to confirm the thermography events. The equipment used to collect the thermograms was an infrared camera with digital image processing, with thermical sensitivity for spectral ranges from 7 to 12 micrometers, appropriate for medical diagnostic utilization; the error index for measurement on this equipment is either 2% or 2oC. It has been used a dynamometer, clock type, for the algometry, commercially available for clinical use, which makes possible to evaluate the applied pressure to the focal point. The trigger point identification was based in a pain diagram filled by the own subject using previously validated parameters. The imaging evaluation was done using a descriptive analysis, having been taking in consideration the thermographic event corresponding to the trigger point, the hot spot or a discoid shaped surface, with one or more degrees Celsius hotter if compared to the neighbor reference point. Algometry was used in this work as reference method It was applied descriptive statistics for evaluate sensibility and specificity in trapezius Myofascial Syndrome diagnoses. A totality of 250 trigger points had been founded: 198 (79.20%) identified by algometry and thermography; 41 points (16.40%) by thermography only; 11(4.40%) identified by algometry only. It was concluded that the thermograpy is an appropriated method for Myofascial Syndrome diagnostic on trapezius muscle.%%%%A termografia, sistema com capacidade de captar a emissividade de luz infravermelha de qualquer superficie reflexiva, faz parte do arsenal atual de instrumentacao em biomecânica. Com esta metodologia pode-se avaliar a fisiologia da manutencao termica atraves de sua representacao cutânea. O presente trabalho teve por objetivo avaliar a termografia comptadorizada na identificacao de trigger points miofasciais, tendo sido escolhido o musculo trapezio como foco de estudo, por esta ser uma das regioes corporais mais acometidas pela Sindrome Miofascial. Esta sindrome e altamente prevalente na populacao adulta ativa e, historicamente, sub-diagnosticada por…


Existing high-resolution satellite image forgery localization methods rely on patch-based or downsampling-based training. Both of these training methods have major drawbacks, such as inaccurate boundaries between pristine and forged regions, the generation of unwanted artifacts, etc. To tackle the aforementioned challenges, inspired by the high-resolution image segmentation literature, we propose a novel model called HRFNet to enable satellite image forgery localization effectively. Specifically, equipped with shallow and deep branches, our model can successfully integrate RGB and resampling features in both global and local manners to localize forgery more accurately. We perform various experiments to demonstrate that our method achieves the best performance, while the memory requirement and processing speed are not compromised compared to existing methods.


Introduction 1. The Rules of the Game 2. Building a Program 3. The Fundamentals-Keeping it Simple 4. Perfect Practice Makes Perfect 5. Drills for Skills 6. The Natural vs. The Average Player 7. Strategy and the Game 8. Mental Preparation and Readiness in the Game and Life 9. My Mentor, My Coach 10. What are You Doing the Rest of your Life


Introduction : The aim of the study was to investigate the physical properties of chitosan-gum Arabic composite films. Material and Method : Chitosans were used in different molecular weights (150 kDa; LMW and 800 kDa; HMW). The films were fabricated by mixing 1% (w/v) chitosan with 5% (w/v) gum Arabic at various ratios (1:0, 1:0.25, 1:0.50, 1:0.75, and 1:1, respectively) and the pH of about 5.5. Physicochemical properties of the composite films were tested on water uptake, water solubility, water vapor permeation and mechanical properties. Results : Results showed that LMW chitosan-gum Arabic composite films having ratios of 1:0.25 and 1:1significantly improved the % water solubility which was 2.2 and 1.8-folds, respectively. Moreover, the ratio 1:0.25 of the LMW composite film indicated significantly higher (p-value<0.05) in swelling behavior at the period of 5, 30, 60, 120, and 240 min compared to the LMW chitosan film. At the ratio 1:1, the HMW chitosan composite film performed significantly increase in water permeability rate (p-value<0.05) at 24 and 48 h in comparison to other ratios of the HMW composite films. In addition, the LMW and HMW chitosan composite films showed lower puncture strength and %elongation compared to LMW and HMW chitosan films, respectively. Conclusion : Due to the various characteristics on physical properties of the composite films, it might be further investigated and developed in appropriated drug delivery systems or other pharmaceutical applications.