In this paper, we present a dynamic diagenetic model of the oxygen consumption pathways and cycling of carbon, nitrogen, manganese, iron, and sulfur in marine sediments. Sixteen dissolved or solid species are included in our model and the vertical transport processes accounted for are molecular diffusion, bioturbation, irrigation, and burial. Adsorption of dissolved species onto solid sediment is assumed to be reversible and to follow a linear equilibrium isotherm. Interactions between species are formulated in 21 biogeochemical reactions that are regulated through simplified Michaelis-Menten kinetics. The key driving input parameter to the model is the transient flux of organic matter supplied to the sediment surface, below which mineralization is described through the well-known 3-G model that includes a fast, a slow, and a non-degradable pool of organic matter. The model was applied to the Arctic sediment of Young Sound in Northeast Greenland using extensive measurements covering a full annual cycle. The model parameterization was performed in a stepwise process, first focusing on parameters describing transport in the sediment and then on parameters related to biogeochemical reactions. The model successfully simulated the measured concentration-depth profiles of O 2 , ΣCO 2 , NH + 4, NO - 3, Mn 2 + , Fe 2 + , adsorbed Fe 2 + , SO + 4, H 2 S, FeS, FeS 2 , MnO 2 , FeOOH, and organic matter; sediment-water fluxes of ΣCO 2 , O 2 , NH + 4, and NO - 3; depth-integrated process rates of denitrification and sulfate reduction; and depth profiles of iron-and sulfate reduction rates. The model application to the Young Sound sediment provided an excellent means to examine whether our perceptions of the most significant transport processes and biogeochemical reactions were correct. The successful simulation of measured data supported their internal consistency and confirmed previously reported interpretations and conclusions. The imposed supply of organic matter to the sediment surface that reproduced the measured data was found to be almost three times higher for the month of July than the average for the rest of the year. The peak in organic matter supply in mid-July coincided with the disappearance of sea ice. A sensitivity analysis performed for the model showed that the rate constants for the two degradable pools of organic matter were among those input variables that most affected the simulated results. As a result, we are confident of the accuracy of these rate constants of 76 y - 1 and 0.095 y - 1 . In comparison with results from temperate sediments, these constants showed no significant correlation to the sub-zero Arctic temperatures. The reproduction of measured data for the sulfur cycle could be obtained only when sulfur disproportionation was included in the model as a sink for S°, indicating that this process plays an important role in the Young Sound sediment.


A was charged with professional misconduct for failure to pay a judgment debt against him. A claimed to have sent a cheque in settlement. A gave evidence, but refused to produce bank documents. The primary submission on appeal was that a disciplinary tribunal had, in effect, reversed the burden of proof by requiring A to prove his innocence. A's duty under the code of conduct was to respond promptly to any request from the Bar Standards Board. 'Respond' plainly means to 'respond positively', not by way of a refusal. The evidence before the tribunal was thus an unjustified refusal. It was for the tribunal to consider what inference it should draw from the refusal. That was not a reversal of the burden of proof. The appeal was dismissed.


According to the control demand of tower crane lifting, a new control method of tower crane lifting by means of VACON converter to control motor is proposed in this paper.VACON converter is of programmable function,which can be used to design special control logic and parameters of VACON-NX.Using VACON converter in tower crane control system makes tower crane start and stop quite smoothly and control system simpler.Actual application proves that the tower crane runs smoothly and has high efficiency,less energy need and so on,whith has very good market prospect..


The judicious use of vasoconstrictors and hypotensive anesthesia has dramatically increased patient safety in orthognathic surgery.1–3 In rare instances, however, the use of vasoconstrictors and anesthetic agents can actually contribute to patient morbidity. A wellrecognized intraoperative example is suddenonset (flash) pulmonary edema. This dangerous and potentially fatal complication has received very limited attention in maxillofacial surgery journals, with only one other case4 reported during an orthognathic procedure. We present an unusual case of intraoperative flash pulmonary edema in a young, healthy woman.


Circular. The Arkansas road company has the necessary legal privileges, in connection with an eligible locality, on Arkansas bay, for making an important port, with the further privilege of making a railroad from Arkansas harbor to Rio Grande. [An appeal for prompt support.]


The present study aims to find out the effectiveness of audio-cassettes in developing the English pronunciation of socially handicapped women – slow learners and to find out whether there are significant differences in the pronunciation of English among the above slow learners with reference to their categories-orphans, deserted and destitute women. The cluster sampling technique was followed to select forty (40) socially handicapped women slow learners studying in Government Service Home in Thanjavur. Statement of the Problem India is one of the emerging super powers in the world. But there are social evils and problems of unemployment. The women are the worst affected because of these problems. Some of them have become orphans, deserted and destitute women. The Government of Tamilnadu have started Service Homes to uplift the above oppressed women to fulfill their basic needs such as food, dress and secured shelter with formal education. The socially handicapped women belong to the various social categoriesorphans, destitute widows, deserted wives, physically handicapped women and women under poverty line between the age group of 19 to 40 years old. Objectives of the Study: 1. To study the effectiveness audio-cassettes in developing the English Pronunciation of the socially handicapped women – the slow learners.


The present invention, at least one high frequency is transmitted through the base in the direction of the liquid film, on a substrate, in particular in capillary intervals, to an apparatus for the method and the present invention embodiment for generating a motion in a thin liquid film.


Background: With the multiple reports of asparaginase-containing regimens used in pediatric ALL therapy achieving a greater survival rate that non-asparaginase treatment regimens used in adult patients, asparaginase therapy is now being increasingly applied in chemotherapy regimens for adults with ALL. One reason for this resurgence is the availability of a long-acting form of the enzyme, pegylated asparaginase, and more recently, flexibility in administration of pegasparaginase via either intramuscular or intravenous routes (Oncaspar®). Given an initial impression in the 1970s that adults were more vulnerable to the toxicities of asparaginase than were children, we assessed the initial experience of intravenous asparaginase in adults with ALL. Methods: The intial experience with pegylated asparaginase at the University of Southern California (USC), Cleveland Clinic, and University of Texas M.D. Anderson Cancer Center were compiled and compared between institutions and with published results in pediatric patients. Results (Table): In 76 adult patients administered 192 doses of pegasparaginase in combination with other chemotherapy agents for ALL, hepatotoxicity was most common, with grade 3–4 elevation of serum liver enzymes and grade 3–4 hyperbilirubinemia in 36% and 14% of the patients, respectively. Hyperglycemia and chemical pancreatitis were next most common, having occurred at grade 3–4 levels in 25% and 5% of patients, respectively. Grade 3–4 toxicities in the 5–10% range were thrombosis, hypofibrinogenemia, nausea/vomiting, and fatigue. Grade 3–4 allergy/hypersensitivity, neuropathy, and CNS ischemia were reported in 1–5% of patients. Conclusions: Intravenous pegasparaginase is hepatotoxic in ∼1/3 of adult patients and has a variety of other, non-hepatic toxicities in


Due to a lack of sufficient theoretical relations, equations for bed load transport in alluvial channel flow have been developed using a variety of empirical assumptions. A linear relationship exhibited in the complex interactions among the three essential components of a river (channel geometry, bed load transport and flow resistance) has led this study to develop a more accurate form of the Meyer‐Peter and Müller (1948, hereafter MPM) relationship, one of the world's most widely used bed load transport equations. This study demonstrates that the application of linearity theory can significantly improve its performance. On the basis of the dataset originally used by MPM, it is shown that the applicable form of the Manning‐Strickler flow resistance relationship can be very satisfactorily determined. The MPM equation is consequently found to be expressible more accurately as Φ = 6[ητb* − 0.047]5/3, where Φ, η and τ*b are the normalized, dimensionless bed load transport rate, bed‐form correction, and flow‐strength parameters, respectively.


LEUKOCYTE alkaline phosphatase (LAP) activity has been assayed under different hematologic and clinical conditions,1 2 3 4 but has generally been used to differentiate chronic myelocytic leukemia f...


A high power amplifier comprises a comparator amplifier having a first input, a second input and an output, wherein a desired voltage is applied to the first input, a voltage of the output terminal is applied to the second input and the output in response to a difference between the voltage is applied to the first input, and the voltage applied to the second input is generated. The high power amplifier also includes a low-pass filter device, which receives a low-pass filtering on the output of the comparison amplifier and executes a conversion device that converts the output of the low-pass filter apparatus in complementary signals, and a push-pull output device, which are driven by the complementary signals and supplies a load with electric power, wherein an increase of the electric current supplied from the push-pull output device is reduced by changes in load due to the low-pass filter apparatus.


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For the emerging 60GHz millimeter-wave communications, the nonlinearity is usually inevitable due to RF power amplifiers operating in the ultra-high frequency and enormous bandwidth, which, in collusion with frequency-selective propagations, poses great challenges to signal detections. In contrast to classical schemes calibrating nonlinear distortions in transmitters, a blind detection algorithm is presented in this investigation, with which both the multipath response and symbols contaminated by nonlinear distortions and multipath interferences are estimated in receiver-ends. The Monte-Carlo sequential importance sampling based particle filtering is used, and the non-analytical distribution is approximated numerically by a group of random measures with evolving weights. By applying the Taylor's series expansion techniques, a local linearization model is further constructed to facilitate the practical design of a sequential detector. Simulation results validate the proposed blind detection scheme. By excluding the transmitting predistorter with complex computations and implementations, the presented algorithm provides a promising signal detection framework in 60GHz systems.


STEM-based learning systems have become commonplace in developed countries today. Students who are taught STEM are expected to be able to realize their imagination and creativity from an early age by directly implementing the basic knowledge gained during school into a real product so that the level of students' understanding of a science can be deep and lasting. Early habituation for schoolage students to get acquainted and plunge into direct practice related to STEM is their main capital in facing future challenges that require adaptation to many new things and a race for creativity that is able to produce innovative products of commercial value and be utilized by mankind. The product resulting from this study received a very positive response from several students who were respondents, although of course, improvements were still needed in terms of the hardware and software that were built.


Higher quality and the increased effectiveness of scientific research play an important part in solving problems in the further development of the socialist economy. The "Basic Directions of the Development of the National Economy of the USSR between 1976 and 1980" - confirmed by the Twenty-fifth Congress of the Communist Party of the Soviet Union — note the need to improve the organization of the labor of scientific workers and to increase its effectiveness: "To increase the responsibility of scientific collectives and their supervisors for the level and quality of research and for the substantiation of recommendations made. To increase the motivation of collectives and personnel in scientific institutions to raise the effectiveness of their activity."


The application of airborne geophysics to provide solutions for engineering problems has increased in recent years. Today's systems are capable of making accurate, high resolution, precisely positioned measurements that give scientists and engineers a better understanding of the geology, hydrology, and natural and manmade hazards. Helicopter geophysical surveys undertaken include: ξ Identifying fractures, faults, near surface bedrock and other geological features. ξ Mapping foundations of earthen structures. ξ Location of aggregate deposits. ξ Detection of pipelines, power lines, contamination and other man-made buried metallic objects. ξ Estimating soil type and depth for pipeline planning, Airborne geophysical surveys are an effective means of reducing the time and cost associated with gaining land access and permission for drilling. Integrated with ground-based measurements and a drilling program, airborne EM conductivity results provide a more complete understanding of ground characteristics. Airborne survey systems provide a multi-sensor platform from which various types of data can be collected concurrently. Multiple-frequency electromagnetic data provide multiple-depth samples, which render a 3-dimensional conductivity image of the ground conditions. Systems can also be equipped with magnetometers, a video camera, laser altimeters and dual-frequency GPS. Various types of data presentations and final products are available such as 2D and 3D images.


Concentrations and annual fluxes of K, Na, Ca, Mg, Al, Fe, Mn, Zn, N, S, P, Cr, Cu, Ni, Pb, Sb, Bi, Cd, Hg, and Tl were measured in the precipitation input to the forest canopy, in precipitation beneath canopy, and in the seepage water below the humus layer and below the tree root zone (output) both in a Central European beech (Fagus silvatica) and in a spruce (Picea abies) forest. Concentrations were determined in an acid loess loam soil from the beech site and in a calcareous little-weathered loess C-horizon for the same elements plus Sr and V. When precipitation was passing through the forest canopy, some elements were partially retained (P, Cu, Fe, Zn, Hg, Cr). The flux of other elements increased during canopy passage. Strong retention of Pb and Ni in the organic surface layer (O-horizon) was found when seepage water passed through it. Within the mineral soil, retention of dissolved elements from the seepage water is observed in the case of K, Ca, Fe, N, S, P, Cr, Pb, Sb, Hg, and Tl. Compared to the unweathered loess, the acid forest soil was nearly depleted of its Ca and carbonate-C contents. A similar, but less distinct,more » decrease was found in the total profile (Na, Sr, V, Cr, Cu, Zn), or in the soil surface layer only (Mg, Al, Fe, Mn, Ni, Co). Carbon, N, P, S, Pb, Hg, Bi, and Tl accumulated in the soil surface layer. The input/output balance showed that both forest ecosystems accumulated all elements entering the system with atmospheric precipitation except Al and Mn. The elements Pb, Hg, Bi, and Tl accumulated mainly within the top soil.« less


Following investigations into the influence of halogens and halogen donor buffer gas additives in high temperature or "elemental" copper vapour lasers [1], a new sub-class of laser has recently been developed in our laboratory based on H2-HCl-Ne buffer gas mixtures. This device, known as a kinetically enhanced copper vapour laser (KE-CVL), typically produces laser output powers 2-3 times higher than from a similar sized elemental copper laser employing a standard H2-Ne buffer gas mix, and at significantly higher wallplug efficiencies [2]. Furthermore, the spatio-temporal evolution of the optical gain and intracavity laser field intensities on both transitions (510.6nm and 578.2nm) is substantially different in the KE-CVL resulting in more uniform radial beam profiles, reduced beam divergence and improved overall beam quality.


For centuries, victories in wars and the fates of nations have been determined more by horses than commanders; moreover, indirectly by blacksmiths who have been caring for steeds' health using methods borrowed from barbers, such as bloodletting and administering laxatives (9). Recognizing the military and economic significance of horses, Claude Bourgelot (1712-1779) founded the first veterinary school in Lyon in 1862. It became an example for successive schools established in Alfort, Vienna, and other cities of Western Europe (11). In Eastern Europe, the first veterinary school was opened at Vilnius University in 1823. In mid-1832, however, both the school and the university were closed by the tsarist authorities, who thus wanted to punish the Poles and Lithuanians for the recent anti-Russian uprising. Their substitute became the Medical and Surgical Academy which began its operation in Vilnius in August 1832. Teaching courses and research were conducted in clinics, departments and auxiliary units of the Medical Faculty of the University, including those belonging to the veterinary school. The Academy trained veterinarians for the Russian army and administration until 1842, when it was finally closed down by decree of the tsar (4). After it closed, the Vilnius veterinary school influenced the development of veterinary medicine in Eastern Europe through its graduates. The heads of veterinary schools, such as Edward Ostrowski (1816-1859) in Warsaw and Kharkov and Napoleon Halicki (1818-1881) in Kharkov, enjoyed the greatest fame (11). The historical works on the animal hospital that was functioning as part of the veterinary school at the Medical and Surgical Academy in Vilnius in 1834-1842 were analyzed and compared with early treatises and doctoral dissertations on veterinary medicine to identify the features of veterinary science in the nascent state. In 1804 Ludwig Bojanus (1776-1827), a graduate of medical studies in Jena and Vienna and the best veterinary schools in Europe, arrived from Darmstadt in Germany to Vilnius in the Russian partition of the former Polish-Lithuanian Commonwealth to organize a veterinary school. However, a lack of appropriately Historia weterynarii History of veterinary medicine


By referring to relevant literature at home and abroad,this paper describe the cause of neonatal hyperbilirubinemia,the monitoring method,the phototherapy and the prevention of complication associated with phototherapy,and the nursing care of blue light treatment for neonatal hyperbilirubinemia,in order to improve treatment efficacy,and reduce side effects.


Short-chain fatty acids (SCFAs; acetate (AC), propionate (PP), and butyrate (BT)) are the primary metabolites of the intestinal microbiota. In addition to being an epithelial energy source, SCFAs exert numerous local effects, including maintenance of the epithelial barrier integrity and protection against inflammation, and are commonly assumed beneficial. It is also well understood that mesenteric lymphatic function is vital for normal gut health; impaired pumping leads to interstitial accumulation of fluid and immune cells, inducing intestinal edema and inflammation. Mesenteric lymphatic vessels are exposed to significantly high concentrations of SCFAs, yet the acute effects of SCFAs on lymphatic function have remained unexplored. Following earlier reports of SCFAs-induced relaxation of vascular smooth and cardiac muscle, in the present study, we tested the hypothesis that AC, PP, and BT reduce lymphatic pumping.Following our recently reported methods, pumping was characterized in vitro using rat mesenteric lymphatic vessels. Briefly, isolated vessels were cannulated, perfused, and bathed with warmed APSS. Following 60-min initial equilibration, in spontaneously contracting vessels, the effects of acute treatment with AC (10 mM), PP (10 mM), BT (10 mM), or AC+PP+BT were determined. In an additional set of vessels, the effects of short-chain fatty acid receptor antagonists (GLPG0974, FFAR2 antagonist, 1 μM and ((R)-3-Hydroxybutyric acid, FFAR3 antagonist, 1 μM) on lymphatic acute responses to AC+PP+BT were determined. Lymphatic responses were characterized using contraction frequency (CF), normalized stroke volume (difference in diastolic and systolic volume normalized to passive volume, NSV), normalized pump flow (CF*NSV, NPF), and diastolic tone (difference in passive and diastolic diameters normalized to passive diameter, DT).Treatment with AC, PP, or BT alone decreased CF and NPF significantly. Accordingly, CF and NPF were also lowered significantly after the combined treatment with the three SCFAs. Nevertheless, both indices were completely restored after FFAR2 and FFAR3 inhibition. Changes in NSV and DT after treatment with AC, PP, or BT, however, were not significant.To our knowledge, the present study is the first to demonstrate adverse chronotropic effects of the three primary SCFAs produced by intestinal microbiota on lymphatic pumping. The lymphatic responses are consistent with reports of reduced heart rate and cardiac contractile indices more than the dilation of blood vessels induced by SCFAs. Further studies are needed to reconcile the apparent conflict between the beneficial effects of SCFAs and the damaging effects of impaired lymphatic pumping. This is the full abstract presented at the American Physiology Summit 2023 meeting and is only available in HTML format. There are no additional versions or additional content available for this abstract. Physiology was not involved in the peer review process.


Summary

Market research renders its services to all functions of marketing. Marketing implies integration of all functions in moving any type of goods or services from production to the final user.

Examples of problems related to the marketing functions, which can be solved by research, are given.

The author says it is a common misunderstanding that market research should always and solely mean the carrying out of field surveys. Remarkable results, however, can already be achieved by a statistical analysis of the company's own sales records and of ready-to-use external statistical information.

The producer who produces for stock and who sells via distributors is interested in an exact knowledge of the needs and the desires of consumers, and of their habits as regards buying and using the product. The sample survey brings him in direct contact with the final consumer.

An example of a method of sequential analysis is given. A considerable economy of costs and time can be obtained in this way.

The author concludes by indicating that market research is a staff-function in the enterprise, and that analysis, interpretation and presentation of the survey-results, ask for the utmost care in order to obtain maximum results of the research performed.


This study presents the design of an observer-based iterative learning control law for linear systems using the stability theory and optimal function. The observer is introduced for states condition monitoring and output feedback. The D-type iterative learning control law is utilised to update the control inputs. Properties of stability, convergence, robustness, and optimality are investigated and demonstrated by stability theory and optimal theory. The convergence properties of the observer-based iterative learning control design are obtained by linear matrix inequalities. A simulation example is used to illustrate the validity and effectiveness of the proposed method.


This paper is to develop a DC-DC converter which can convert high battery voltage into low DC voltage supplied to the electric system of the eco-friendly electric bus. As the electric bus parts have large capacity and the larger difference between input and output voltages comparing to those of the passenger cars, high capacity power converter is required. In order to implement the circuit, we have applied full-bridge converter topology. In order to achieve the high efficiency, we have also performed control with zero voltage switching using phase shifted method. Moreover, we could implement a converter that has characteristics including high output density, high performance, small size and lightweight through optimal design of high frequency switching, transformer and inductor. We fabricated a prototype to satisfy design specifications and could achieve objectives of small size and lightweight from test results of 40kg in weight and 22.95 liters in volume. Especially, we achieved high efficiency of 91%.


Abstract. In the case of poor lighting conditions, it is easy to capture the underexposed images with low contrast and low quality. Traditional single-image enhancement methods often fail in revealing image details because of the limited information in a single-source image. A single underexposed image enhancement method based on adaptive decomposition and convolutional neural network (CNN) is proposed. The CNN training models only need images with different brightness rather than a strict ground-truth image. First, a simple effective synchronous decomposition method is proposed to solve the synergy problem in multisource image decomposition. Then, two CNN models are designed for the high-frequency part and low-frequency part, respectively. They process the high-frequency and low-frequency sub-bands, instead of the entire source images. The weight map obtained from the CNN model represents the contrast distribution. The exposure map generated by gradient-based visibility assessment indicates the exposure distribution. Finally, the weight map and the exposure map are multiplied to generate the final decision map. Experimental results demonstrate that the proposed method outperforms competing methods.


Objectives: Driven by a growth of single-person households and individualized lifestyles, solo dining in restaurants is an increasingly recognizable trend. However, a research gap exists in the comparison of solo and group diners' menu-decision making processes. Based on the self-control dilemma and the temporal construal theory as a theoretical framework, this study compared the ordering intentions of solo vs. group diners with healthy vs. indulgent (less healthy) entrées. The mediating role of consumption orientation and the moderating role of amount of menu nutrition information were further explored to understand the mechanism and a boundary condition.


First, in the introduction, we will show the urgent need to create neuron-calculators (NCs) for the normalized equivalence of two matrix arrays for self-learning equivalently-convolutional neural networks (SLE_CNNs), video processors for parallel image processing with enhanced functionality. Consider promising areas of application of such single and multichannel neuron-calculators as high-precision, high-speed and high-performance accelerators for hardware systems and architectures for recognition, classification, image categorization, in particular for 2D-image space-invariant associative memory structures, SLE_CNNs based on the equivalence paradigm. Next, we will consider and analyze the theoretical foundations, the mathematical apparatus of matrix and continuous logic, and their basic operations, show their functional completeness, evaluate their advantages and prospects for application in the design of biologically inspired devices and systems for processing and analyzing signal arrays. We will show that some functions of continuous logic, including operations of normalized equivalence of vector and matrix signals, operation of the bounded difference of continuous logic, are the powerful basis for designing advanced accelerator calculators, microcells for hybrid (mixed) analog-to-digital transformations, comparisons and calculations of characteristics. Next, we will consider in more detail the design and simulation aspects of such digital neuron-calculators for the normalized equivalence of two matrix arrays based on FPGA, including their various modifications, depending on the dimension and the number of compared arrays. We will propose our approach for calculation of the normalized equivalence functions comparing current fragments of images and filters with dimensions 3×3, 7×7, 15×15, and others. The project is executed on FPGA ALTERA MAXII. The simulation was done with Intel Quartus Prime 17 and showed that in a single chip it is possible to place four parallel working neuron calculators processing 4 filters with a size of 15×15. The approximate processing time is less than 5μs. Power consumption is 50mW for supply voltage of 2.5V and clock frequency equals to 50MHz. We will also consider modifications that improve performance for different filter size. We show the results of modeling the proposed new implementations of NCs, we estimates and compare them.


Earthquake is a kind of natural disaster, which will have a great impact on the building structure. In the vibration control field of building structures, the timeliness of system stability is extremely important. In traditional control methods, the timeliness is not paid enough attention for systems with uncertain seismic waves. For setting this problem, fuzzy adaptive compensation control for uncertain building structural systems by sliding-mode technology is proposed. It is combined with fuzzy adaptive control and sliding-mode control to ensure that the system can be stable with satisfied timeliness. Also, saturation function is used to ensure the feasible physical implementation of the control system. Compared with the traditional LQR (linear quadratic regulator) control, the simulation results showed that the proposed method can make the system reach a stable state with rapid convergence performance and has a feasible physical implementation.


In this paper, based on the study of f-distributor in (1), we defined the concept of f-center and discussed some properties of f-center. As an application of these properties, we generalize some properties of p-center and center of groups.


You may download books from tricksyard.com. Project is a high quality resource for free PDF books.As of today we have many Books for you to download for free. You can easily search by the title, author and subject.Look here for bestsellers, favorite classics and more.This library catalog is an open online project of many sites, and allows users to contribute books. No registration or fee is required, and books are available in ePub, Kindle, HTML and simple text formats.


Introduction: Peoples all around the world are waiting for vaccination against COVID 19 infection. In Bangladesh, Astra Zeneca (AZ) vaccine was provided, but patients had infections of SARS COV 2 even after vaccination. We focused on observing the severity, oxygen requirement and outcome of the COVID-19 infected patients who took the first dose or completed the immunization regimen. Methods: This is an observational study done among 174 COVID 19 patients from three COVID 19 dedicated hospitals of Chattogram, Bangladesh, who took AZ vaccines 1st dose or completed the schedule. All patients were Real-Time Reverse Transcription Polymerase Chain Reaction (rRT PCR) positive for COVID 19. Patients were enrolled after receiving written informed consent. Suspected cases or unwilling patients were excluded from the study. Ethical approval was granted by the CMOSH ERB. SPSS 20 was used to analyze the information gathered. Results: Among 174 vaccinated patients, 55(31.61%) completed the vaccination schedule, and 119(68.39%) took their 1st dose of the COVID 19 vaccine. Gender distributions revealed 67(38.5%) female and 107(61.5%) male got the vaccine, and 55 patients completed the full two doses, and 119 patients took the 1st dose. Most of the patients were 40 years and above. In the completed vaccination group, 33(60.0%) out of 55 in and in the first dose vaccinated group, 75(63.0%) out of 119 had a mild COVID 19, and severe and critical cases were found very minimum. Among the patients who have completed the vaccination, 32(58.2%) needed no oxygen, and who was given the first dose, 78(65%) needed no oxygen. No death occurred who completed the vaccine, and 3(2.5%) patients died who took 1st dose of the vaccine. Conclusion: Vaccine provided in Bangladesh to the people so far seems safe and effective. Severe and critical COVID 19 is low, and the need for oxygen to admitted patients is less, and the death rate is minimal.


PURPOSE: A system for providing an advertisement through a medium of video executed on a smart device and a method thereof are provided to trace a movement route of an object including a medium of video, thereby receiving an advertisement by anyone. CONSTITUTION: An annotation unit(100) traces advertisement information of an interested object and a movement route of the interested object. The annotation unit annotates the movement route designating the interested object. The annotation unit saves the annotated movement route. A display unit(200) displays saved annotation information and a medium of video. The display unit receives a selection signal of a user. A management server(300) analyses the annotation information from received video information. And then analyzed annotation information is distributed and saved.


The focus of the research is on the psychology of a pilgrim who is seeking an ecstatic experience at a religious site. The scriptures have inspired a pilgrim, and the pilgrimage to holy destinations to relate the locations as mentioned in the scriptures. The study aims to establish a correlation between authentic experience and destination preference. Cognitive approach has been adopted to understand human psychology and corresponding destination preference has been identified. The purpose of the assessment is to find out which place in a religious city is the most popular among pilgrims. Results of the perception survey has been analyzed and further spatial configuration of the identified locations has been documented through physical mapping. It has been observed that the locations which are dominant in natural elements are mostly liked by the pilgrims.


This article is to determine the necessity and urgency of content compilation of computer science course for the students according to their specialties in higher educational institutions. In particular, it was determined by the analysis of educational program for the students of economic specialties that the content of the computer science course should have both fundamental and variable parts. A fundamental part should provide the extension of existing knowledge and skills acquired in school until the level required for study of a material of a variable part and the variable part should ensure the study of the specific subject appropriate to the economic specialty. Therefore, the general factors affecting the acquisition of knowledge and skills required for prospective economist and related with implementation of information technology were underlined. To achieve these objectives, the general technique of expert compilation of the best possible content of educational program based on the analytic hierarchy process technique of T. Saaty has been considered.


The present paper discusses the evolution of the legal frame of public-private partnership in Peru, putting accent in the incentives given to private investment made by these specific laws. For that purpose, the paper makes a meticulous analysis about the progressive inclusion made on the matter. Finally, a practical case is presented.


DISCOVERY OF HLA-B27 It was Erik Thorsby from Norway who first described HLA-B27, originally named TH-FJH. It was detected by using an antibody that was produced by "planned immunization," a method that was being used by several investigators. He immunized a colleague, FJH, with a skin transplant and cells from a healthy donor who was HLA identical with the recipient because Eric assumed that the donor might possess a hitherto undetected HLA antigen. The recipient produced an antibody that detected a "new" antigen, which he named TH-FJH, and this antigen was later given the name HLA-B27. Erik told me that later when he tested his own family, he noticed that one family member who carried this new antigen had AS, whereas another had questionable AS (personal communication). However, since most of his family members who carried the new antigen were completely healthy, he discarded this finding as being caused by chance. He has ever since regretted that he did not pursue this possible association by testing some other patients who suffered from AS. Had he done so he would have been the very first to detect an association between an HLA antigen and a disease!


In this work the alternative method for the description of the elastic scattering of the systems 160 + 160 and 160 + 12C in a wide range of energies is offered. The repulsive core is introduced for the more correct description of angular distribution of back angles. The analysis of dependence of value of the core from energy is provided.


Datasets obtained from lunar occultation in the thermal infrared with a classical direct imaging system are compared to those obtained with a two telescope interferometer. Angular resolution and sensitivity achievable with ESO's VLT- Interferometer as λ≈10 μm are roughly identical to the precision with which 1-dimensional cuts can be reconstructed from lunar occultations. Prototype results obtained at a 4m class telescope with lunar occultation only are presented. The concepts of an algorithm to reconstruct interferometric data under the constrain of compatibility with a light curve derived from a lunar occultation event is given. The improvement of image reconstruction of the combined data set relative to the single data sets is demonstrated by calculating theoretical point spread functions. The estimated 'PSF' width for this technique at λ≈10 μm is of order of 0.03 inches.


There is an increasing demand on our ability to understand how international military forces may improve their effectiveness in coalition operations, while simultaneously national defences forces have to make investment trade-offs in order to achieve highly networked capabilities both across their own forces and in coalition with allied forces. This reality places new demands on defence analysts to make rational judgments and decisions on investment trade-offs across a much wider scope than has been traditional in defence operational research. For example, the process of dynamic formation of mission groups involves much more than just physical capabilities and bandwidths. Rather, it is intricately and inseparably linked to the cognitive, organisational and socio-cultural aspects of human interaction. Though much is already known about these problems, both from research and operational experience, virtually none of this knowledge can be brought to bear through existing analytic tools. In this paper we will describe the trade-space problems facing defence analysts in both UK and Australia, and how they may be addressed through the joint development of the DARNSTORMS model, integrating the Australian DARNOS model and the UK STORM algorithm. This paper is the first of three being offered to the Symposium; the other two will focus on theoretical synthesis and implementation issues.


Zinc of an essential trace element plays an important role in regulating carbohydrate metabolism, and acts both structurally and catalytically in metalloenzymes that are Zn metalloenzymes as important hydrolase of catalyzing hydrolysis [1]. Zinc homeostasis is primarily controlled via the expression and action of 14 protein transporters that increase cytoplasmic zinc (Zip1-14) and 10 protein zinc transporters that lower cytoplasmic zinc (ZnT110), which zinc deficiency as well as zinc excess can result in increased susceptibility to infections and development of especially inflammatory diseases [2]. Zinc deficiency can also induce apoptosis by disrupting growth Abstract: Anti-cancer vaccine activities of zinc(II) for cancer prevention, malignancy, angiogenesis, and metastasis have been investigated. Therapeutic cancer vaccines are designed to generate a targeted, immunemediated antitumor response. The immunoprevention is a fresh approach to cancer prevention based on the stimulation of the immune system before tumor onset that vaccines made of cells or DNA plasmids combined with appropriate adjuvants completely blocked mammary carcinogenesis. Zinc fingers induced preventive cancer vaccine is capable to induce effective immunity against malignancies, in which the tumor prevention is indicated by anti-tumor of suppressed tumor growth and human clinical trials are evaluated its applications as a vaccine for patients with tumor gene cancers.


A grid of 3 ft X 3ft plots separated by 1 ft wide buffer strips was used for this test, at a golf course in Belmont, MI. The plots were located on irrigated rough with sandy soil. Each treatment was replicated six times. Granular insecticides were applied with modified "salt" shakers. Insecticides were mixed with 1500 ml of water and applied at a rate of 137 ml/9 ft2 (175 gal/acre) with a single nozzle, hand-held wand C02 sprayer from R&D Sprayers. Insecticide applications were made at 50 psi through an 8003 flat fan nozzle. The nematode treatments were applied at 10 psi through an 8008 flat fan nozzle. The plots treated with nematodes were watered immediately after application with 1/2 inch of water applied with a watering can. All treatments were applied on 9 Sep except Merit which was applied on 24 Aug. Evaluations were made on 12 Oct by digging up a 14 inch x 14 inch area and counting all live grubs. Replications 5 and 6 were dropped from all treatments for analysis as they had very low counts.


This study aims to obtain fundamental understandings involving the manufacturing processes of nano-composites with chemically surface-modified multi-walled carbon nanotubes(MWCNT), and explore the role of functionalized MWCNTs in the epoxy/MWCNT composites. For this purpose, MWCNTs were purified by the thermo-chemical oxidation process, and incorporated into an epoxy matrix by in situ polymerization process, the surface of MWCNTs were functionalized with carboxyl functions which were demonstrated by an infrared spectroscopy. The mechanical properties of epoxy/MWCNT nano-composites were measured to investigate the role of a chemically functionalized carbon nanotubes. To improve the dispersion quality of MWCNTs in the epoxy matrix, methanol and acetone were exploited as dispersion media with sonification. The epoxy/MWCNT nano-composites with I or 2 wt.% addition of functionalized carbon nanotubes show an improved tensile strength and wear resistance in comparison with pure epoxy, which shows the mechanical load transfer improves through chemical bonds between epoxy and functionalized MWCNTs. The tensile strength with 7 wt.% functionalized MWCNTs increases by 28% and the wear resistance is dramatically improved by 100 times.


Introduction: On October 1, 2017, a gunman fired on a festival in Las Vegas, Nevada, killing 58 people and wounding over 500. Multiple casualties were received at two nearby hospitals that sponsor residency programs: Sunrise Hospital and Medical Center and University Medical Center. Aim: To evaluate the impact of the most lethal mass-shooting event in US history on graduate medical education (GME) at the involved hospitals. Methods: Anonymized surveys were sent to 210 physicians at SMC and 110 physicians at UMC. Surveys incorporated 4 validated instruments: The Post Traumatic Growth Inventory (PTGI), The Impact of Events Scale-Revised (IES-R), The Multidimensional Scale of Perceived Social Support (MSPSS), and The Team Cohesion Factor (TCF). Results: Sixty-six physicians completed the surveys (38 attendings; 17 residents). 10% of physicians scored in the likely posttraumatic stress disorder (PTSD) range and 15% found themselves avoiding or struggling with managing similar patients, though overall survey response rate was low. The majority of physicians did not believe the event impacted their specific GME activities. No attending physician rated the event as negative in terms of global impact on GME, and 34% rated it as positive. However, 12 of 17 residents rated the event as a hurdle in its GME impact. A regression model predicting the IES-R score demonstrated a trend that those with higher pre-event stress and lower social support reported more adverse impact (p<0.06). Discussion: We believe our study is the first to examine the impact of mass casualty traumatic events on graduate medical education. Attendings and residents differ in their global perception of the impact, with attendings viewing it as a positive event and residents as a challenge. Pre-event level of stress and perceived social support predicted the impact of the event and may partially explain these results if residents and attendings vary on these parameters.


Dec. 13, 1962. 5 pgs.
Editorial: Solitary York student pickets Don Jail, urges S.C. "to commit this
University to active opposition to the Death Penalty until it no longer exists
in Canada." This editorial affirmed P-T's intent to take a stand on" "and cause
of importance to man and his community."
Montreal students riot over statements by Donald Gordon, President of C.N.R.,
which were anti-canadiens. "Students are capable of taking an active interest in what is going on in the world."
Contributors: Rob Bull, Ken Mac Gray, Merrill Shepherd, Bill Collins, Mike McMullen, George Rust d'Eye
Editors: Doug Hird, Harold J. Levy, Allan Millward,
Sports: Dave Allen
Circulation: Lillian Hale
Distribution: George Rust d'Eye
Rewriting: Steve Bakrer
Mortician: Janet McQuillan
Typing: Trudy Lipp and Delle McClennan
Proofreading: Patti Heffron and Fred Gorbet
Printing: Mary Lynne Arneson
Solitary York student pickets don jail
Corporation head fears ideology threat
Editorial II
Montreal students riot
Editorial III
Voting behaviour by Rob Bull
Athletic briefs by Dave Allen
York humbles architecture
Heavenly days part II
A note of appreciation
Six tow on campus
Letters to the editor
Le coin Francais by Aube
Mariner arrives by Ken Mac Gray
Masses swamp debating society
Wanted: two "whole men"
Pro Tem interviews shaft inspector by R. Bull
"Varsity" editor interviewed


Now more than ever, we have begun to appreciate the roles of individual physical and genetic variation in health and medicine. A great deal of research attention has recently been devoted toward personalized medicine, in which technologies like medical genetics are used to determine information such as how a patient is likely to respond to a treatment or the optimal dose of a drug. While drug therapy will undoubtedly advance as a result of this new focus, it is critical that we not overlook the importance of personalized nutrition in disease management and health promotion. Indeed, personalized nutrition may be even more critical than personalized medicine given that dietary intake is a fundamental part of everyday life that affects our health. The fields of nutrigenetics and nutrigenomics present uniquely powerful sources of information for implementing personalized nutrition. Nutrigenetics specifies how individual genetic variance impacts response to nutrients such that an individual can avoid negative metabolic consequences by choosing appropriate foods. One classic example is lactose intolerance, in which one lacks the lactase persistence allele and therefore cannot digest lactose [1] . Thus, this person's health would benefit from avoiding foods containing lactose. On the other hand, nutrigenomics explores how nutrients affect gene expression, so that ingesting certain nutrients according to an individual's health condition can normalize their diseaserelated gene expression. For example, increased systemic inflammation is linked to an upregulation of inflammatory cytokines (e.g. TNF , IL-1, IL-6), which can in turn be suppressed by some nutrients (e.g. omega-3 fatty acids [2] ). The key element linking these 'sister' fields is the concept that nutrients interact with an individual's genetic profile to impact their health. Thus, as each individual has their own unique genetic profile, this knowledge is essential for developing personalized nutrition. The critical prerequisite for personalized nutrition is the ability to precisely detect and interpret an individual's metabolic and health status by way of metabolic biomarkers. These


Introduction: Aging and middle aged population growth and increase in life expectancy, has changed the attitude towards elderly. However, decrease in cognitive performance of aged people has always been under investigation. This study was carried out to investigate the effect of working memory software on self-esteem, self-concept and middle aged memory. Methods: This experimental study was carried out based on pre-test and post-test on experiment and control groups in Isfahan, Iran. 50 middle aged people were selected randomly and divided to experimental and control groups (25 people for each group). Measurement tools in this study were Wechsler memory scale for adolescents, Rogers's self-concept and Aizeng self-esteem. Results: Covariance analysis showed a significant difference in self-esteem, self-concept and control groups. But, after the software education, the differences in experiment group were higher. Conclusion: Working memory software could strengthen middle age working memory, and upgrade their life style


The investment casting technology has been the most common way in the titanium alloy casting.In this paper,the research status of refractory and binder used for the titanium alloy investment casting shell mold was introduced.Then the influences of coating preparation,shell mold drying and shell mold roasting on the shell mold quality were pointed out.


Abstract When conventional illustrations tell readers what to imagine, critical visual literacy is compromised. The ideal relationship between illustrations and words in children's picture books involves a relationship where neither dominates the other (Nodelman, 1988). But when illustrators lean on conventional images readers lose opportunities to interpret. Three avenues for critically re-examining the conventional visuals in the rhyme "Humpty Dumpty" are explored: historical analysis, questioning the text, and visualizing with other nursery rhymes. We can re-open closed interpretation, challenging the way powerful illustrations can shut down the visualization process.


ABSTRACT The major components of the volatile leaf oil of Juniperus convallium Rehd. &Wils. Were found to be α-pinene (47.6%), myrcene(8.4%), limonene(5.1%), abietadiene (4.7%), abietatriene (4.7%) and cubebol (3.3%). The oil is somewhat unusual in containing several cubebenes, cubebols and cubenols.


Ferroelectric thin films have been studied for applications in random access memory (RAM). Owing to the decreasing feature size and increasing density of integrated circuit devices, the requirements for patterning techniques suitable for the fine features of bottom electrodes have been increased. Platinum (Pt) has been the most widely used electrode material for ferroelectric capacitors due to its good thermal stability and low resistivity. Several studies have been reported on the etching of Pt thin films using CF/Ar chlorine-based chemistry and H/sub 2/S/HBr gases. In this study, we have used SF/sub 6/ gas chemistry in the etching of Pt thin film and compared this with the etching characteristics with Cl/sub 2/ gas chemistry.


The ethnography of human–object relations in native Amazonia can help to illuminate the role of technological artifacts in modern society. Rather than abandon the categories of "subject" and "object" and of "Society" and "Nature," as suggested by proponents of "the ontological turn," anthropologists can compare subject–object transformations and the naturalization of social power relations in the two contexts. In native Amazonian animism the attribution of subjectivity and agency to artifacts often includes personhood and intentionality, while in modernity technological objects tend to be perceived merely as autonomous agents, but both these kinds of perceptions can be understood as statements about fetishized social relations. In the former case an external observer can conclude that the delegation of agency to artifacts is dependent on human consciousness, while it is generally believed that technology operates independently of human perceptions. However, in acknowledging the ultimate dependence of modern technology on exchange rates and financial strategies in a globalized economy, we realize that the agency of modern artifacts is also dependent on human subjectivity. In shifting the focus of comparative anthropology from ontology to political economy, we can detect that modern technology is a globalized form of magic.


Objective:To examine the performance of chitin in its action against mutagenesis. Methods:High quality lima beans were selected and budded. The roots were collected and observation of the change of the rate of their microkernel occurrence was made via negative and positive contrast. Results:Chitin can not only decrease the rate of microkernel occurrence in the lima bean roots, but also repair the root cells damaged by immunity depressant. Conclusion:Chitin has a strong ability of counteracting mutagenesis.


This article is about the solidaric perspectives from an NPO management point of view. The reflection includes the frame conditions in social and health work at one side, and relates this at the other side to the term of solidarity as developped by Ulf Tranov. The forms and possibilities of solidaric action are discussed along the experiences oft he author, who works in the field of psycholocigal mens counseling and health work. The potential of solidarity is seen in areas like cooperation in gender issues, handling of temporary project work programs, or how to deal with under- or unpayed work on neccessary NPO structures. In this reflection, it becomes quite clear, that beside some forms effective practices, a broader social change is needed, for influencing and solving structural given conflicts, even when doing the best from a solidaric point of view.


Purpose: To quantify the dose enhancement (DE) in tumors labeled with contrast medium and irradiated by kilovolt x-rays in Contrast-Enhanced Radiation Therapy (kV-CERT). To study the microdosimetric changes in radiation quality in the same. Method and Materials: DE in the presence of contrast media (CM, I or Gd-based) in slab geometries was studied with a Monte Carlo model (validated against measurements) as a function of photon energy and concentration. Two simulated clinical test cases were studied for a spherical tumor labeled with CM embedded in the brain or lung region. In both cases a CT-like arc was used as source geometry. To investigate microdosimetric radiation quality changes in the CM regions dose mean lineal energy, yD, was calculated. Results: In slab geometries irradiated with mono-directional x-ray beams maximum DE of about 6–8 for a I-based solution (50 mg/ml) or a Gd-based solution (79 mg/ml) were found to occur for 60 keV photons. Dose uniformity in the slab was found to depend strongly on the contrast medium concentration, the depth in the slab and the photon energy. For the brain and lung test cases dose enhancements of 4–6 were found when realistic x-ray spectra were used in an arc irradiation. A variable dose rate at different angles improved the dose uniformity in the target. For the lung test case kV-CERT was compared to a conventional 6 MV AP-PA plan. In addition to the large dose enhancement in the tumor, a dose decrease in the surrounding tissue by about 50% was noted. The changes in dose mean lineal energy in labeled tumors were limited to about 10%. Conclusion: kV-CERT is a technique that has the potential to enhance the dose to tumors significantly while reducing the dose to the surrounding healthy tissues. Conflict of Interest: Work sponsored by Siemens Medical Solutions.


A method for the compensation of surface acoustic wave (SAW) oscillators is described. This work is a development of a technique first used for compensation of AT-cut bulk crystal oscillators. The benefits that result for SAW oscillators are high compensation performance, low power consumption, low complexity and relatively low cost. Compensation is achieved by the use of a custom bipolar integrated circuit which generates a power series representation of the control voltage of a voltage-controlled SAW oscillators. A prototype oscillator has been built at 600 MHz and shows a compensated performance of +or-4 p.p.m. over a 120 degrees C operating temperature range. The potential to improve the performance to +or-2 p.p.m. exists.<<ETX>>


Audit of fixed assets is necessary to improve the competitiveness of universities.What's more,it's also the urgent needs of higher education massification.Therefore,audit of fixed assets become an urgent task for unniversities.The author argues that universities should specify the increace and reduction links,the internal control and inventory system to improve the audit system of fixed assets in order to upgrade the service quality.


Hans Vande Sande, Kay Hameyer and Ludo Froyen KULeuven, Dept. ESAT, Div. ELECTA, Kasteelpark Arenberg 10, B-3001 Heverlee-Leuven E-mail: firstname.lastname@example.com It is customary in computational electromagnetics to directly implement material characteristics under the form under which they are given by the steel factories. As the measurements of such characteristics involve generally only scalar quantities, their implementation as such in a magnetic field finite element program constitutes a 'de facto' generalization, which is not backed by any arguments nor even mentioned. Measurements give only a partial view on the complex behavior of matter (and in particular that of iron and steel). They need therefore to be interpreted in the context of the mechanisms in play at the microscopic level. The purpose of this paper is to propose such an interpretation in the case of the analysis of the anisotropy of laminated steels. For anisotropic materials, the vectors representing the magnetic field


Teacher is the main actor who has important role in problem solving in every learning process. The problem solving can be done through research studies. Uniquely, teachers' research reports in Indonesia are more done by the male teachers than the female teachers. Teacher comes from a trained pre-service teacher. Research skills are obtained when they become pre-service teachers. This research exploring belief in the research skill of pre-service teacher and showing the difference of research skills based on gender. The method used was through some surveys on a Likert scale. This research skills questionnaire was measuring as follows: planning, choosing problems, studying literatures, choosing instruments, collecting data, choosing method and analyzing data, interpreting data and concluding research result. Samples were chosen from random sampling consists of 22 males and 140 female's pre-service physics teachers of university in Lampung. The results showed that the average value of different test for each aspect of research skills obtained p-value ≥0.05. The conclusion that pre-service physics teachers have good research skills of average value = 4.03, there is no significant difference by gender. The result of this survey can be used in developing research skills of pre-service teachers, especially in publication of article.


Some features of the molecular weight distributions found by experiment for low pressure polyethylenes are examined; an analytical interpretation of them is suggested which is in agreement with the polymerization mechanism resulting from kinetic investigations of Natta and co-workers. Such interpretation is based on the consideration of the distribution of the individual times of growth (or of the "lifetimes") of the single macromolecules. It is assumed that (a) these lifetimes tend to be distributed according to the Gauss formula, such as a series of events tending to be distributed at random about a mean; and (b) the growth of any single macromolecule proceeds at a rate which can be considered as the rate of a chain reaction. Possible deviations from such simplified scheme are taken into account. A distribution formula of a generalized Lansing-Kraemer type is deduced, giving an explanation of all the observed features of the molecular weight distribution.


This research is about estimating the influence of naturalresources and school graduation rates and the number ofworkers on economic growth in Indonesia. The model usedis multiple linear regression with one dependent variable andfour independent variables. The method used is the OLS(Ordinary Least Square) method, where the estimatedparameters of the models are verified by statistical tests. Thevariables used in this study include the length of time forschool graduation, the number of labor (labor), miningproducts, and PMTDB (formation of gross domestic fixedcapital). The results of data processing show that naturalresources (mining products) have a positive contribution toIndonesia's economic growth. From the last analysis that theschool graduation rate also has a positive relationship toeconomic growth.


Endoscopic skull-base surgery has grown dramatically over the past several decades. While the number of articles published in the field has increased from 90 to over 1000 per year since 1990, these metrics fail to encapsulate the equivalent expansion in techniques used to innovate and study the subject. This issue of the International Forum of Allergy & Rhinology (IFAR) represents a microcosm of the intellectual fecundity of the investigators who continue to improve techniques and outcomes in skull-base surgery. Faden et al.,1 from the Pittsburgh group, tackle the challenging topic of diagnosis and management of pseudoaneurysms of the petrous, cavernous, and clinoidal segments of the internal carotid artery through a retrospective analysis and literature review. Up to 20% of cases of arterial injury during endoscopic endonasal approaches may develop pseudoaneurysms.2 This article focuses on the more rare cases of nontraumatic pseudoaneurysm, for which the authors recommend endoscopic management following angiography, and endoluminal intervention in cases where the diagnosis and/or etiology necessitates further confirmation or when decompression of adjacent structures is required. Perioperative management of patients following endoscopic skull-base surgery remains highly variable and, to date, no widely-accepted evidence-based guidelines exist. Roxbury et al.,3 from the Cleveland Clinic group, attempt to characterize the variability in perioperative care using a survey of North American Skull Base Society members and achieved a response rate of 17.8%. Of the 116 responders, the majority of surgeons did not use lumbar drains and employed the use of the nasoseptal flap in the setting of intraoperative cerebrospinal fluid (CSF) leak. Similarly, the use of rigid reconstruction including bone and cartilage was reported at only 20% regardless of the flow state of the CSF leak. These responses are reflective of my own views of skull-base reconstruction in the post–vascularized flap era where the utility and reliability of the nasoseptal flap has begun to replace some of the adjunctive procedures used historically to minimize CSF leak. In keeping with the theme of advances in mucosal flap reconstruction,


Thank you for downloading the face of time. As you may know, people have look numerous times for their chosen novels like this the face of time, but end up in infectious downloads. Rather than reading a good book with a cup of coffee in the afternoon, instead they juggled with some harmful virus inside their laptop. the face of time is available in our book collection an online access to it is set as public so you can get it instantly. Our digital library hosts in multiple countries, allowing you to get the most less latency time to download any of our books like this one. Merely said, the the face of time is universally compatible with any devices to read.


THIS is not a discussion on multiple pregnancy, or on the causes of foetal wastage in twin delivery. Here an attempt is made to stress the definite fact that in modern obstetric practice the second twin is at greater risk of death than the first. The subject is not new. Yet its significance continues to meet with doubt in some quarters and with inadequate appreciation in others. It is time that the relevant facts were accepted more universally in their proper perspective.


In this work, an extraordinary acoustic transmission transparency window with an angle-insensitive acoustic metamaterial plane is proposed and investigated numerically and experimentally. The cell of the metamaterial plane consists of two embedded and coaxially split spherical shells arranged in a square lattice, and the extraordinary acoustic transmission transparency window is caused by the resonance coupling of two embedded split spherical shells. The simulation results reveal that the designed plane has a frequency-selective transparent window with angle insensitive to incident waves. To obtain experimental evidence, the designed samples are fabricated by three-dimensional (3D) printing technology and measured using an acoustic impedance tube testing system. The transmission exported from the experiment coincides with the simulation predictions, which further proves the existence of the acoustic-frequency-selective transparent window caused by the resonance coupling. This phenomenon revealed in the present contribution is widespread and is expected to be utilized for fabricating and designing novel acoustic devices.


A detailed study was performed on the age and sex differences in the activity of the enzyme in the livers of rats which catalyzes the oxidation of thiophosphates. It was found that the enzyme activity of the livers of adult males was 2 to 3 times greater than that of adult females of the same age. No sex difference in enzyme activity was noted in animals less than 30 days of age but the activity of the livers of male rats exhibited an abrupt increase between 30 and 60 days of age which corresponds to the age of puberty in male rats. The low enzyme activity of the livers of adult females and young males was increased by prolonged administration of testosterone and the high activity of the livers of adult males was decreased by castration and by the prolonged administration of progesterone and diethylstilbestrol. The results of these experiments indicated that sex hormones influence the synthesis of the thiophosphate-oxidizing enzyme. The activity of the thiophosphate-oxidizing enzyme of the regenerating livers of male rats was markedly decreasedat 4 days after partial hepatectomy but gradually returned to the normal level within 20 days. The low enzyme activity of the livers of adult females, weanling males and partially hepatectomized males is increased to the level of adult males at 24 hours after the administration of 25 mg/kg of 3-methylcholanthrene. 3,4-benzpyrene and 1,2,5,6-dibenzanthracene also increased the activity of the livers of adult female rats. The administration of ethionine inhibited the response to the hydrocarbons. The inhibition of cholinesterase caused by the intraperitoneal administration of 2 mg/kg of guthion was increased by approximately 50% at 48 hours after injection of methylcholanthrene. The intraperitoneal administration of 20 mg/kg of β-diethylaminoethyl diphenylpropylacetate (SKF 525A) 40 minutes before injection of 2 mg/kg of guthion markedly decreased the inhibition of cholinesterase and reduced susceptibility to the acute toxicity of guthion. These effects are explainable on the basis of the ability of SKF 525A to inhibit the enzymatic oxidation of thiophosphates. Feeding a protein-free diet to adult male rats reduced the ability of the liver to convert guthion to an anticholinesterase agent by 75%. The increase in activity of the thiophosphate-oxidizing enzyme which occurs after the administration of carcinogenic hydrocarbons was inhibited when the animals were fed a protein-free diet.


This thesis presents a detailed analysis of lean implementation at Hamilton Sundstrand, a global supplier of technologically advanced aerospace and industrial products. The main objective of the internship was to convert from a push system, where orders are expedited and scheduled at multiple points in the process, to a pull system driven by a bin size or finished goods supermarket. Some of the key issues addressed include system design for highly variable processes, experimentation with various forms of Kanban, and the use of value stream mapping as a change management tool. This thesis is divided into two separate projects, both directly related to pull production. The first assignment was to redesign a subassembly process to improve fulfillment at the downstream assembly operation. Broader in scope, the second task involved implementation of a constant work-in-process scheduling system or CONWIP. Each project was designed and executed through value stream mapping and continuous improvement. The following discussion focuses on both strategic and tactical challenges of lean transformation because analysis and implementation were equally important throughout the internship.


Recent evidence shows that the terrain features of the moon are due both to cosmic and endogenic processes. Those features of the moon are classified according to their origin. This is also done for several volcanic features on the Earth.


After prolonged irradiation of trans-α-ionone (I) in ethanol two new isomers IV and V (cf. Table I) can be isolated.


"Danging from Suez to far Calicut on the western shores of India, dotted down the east coast of Africa, along the barren reef-scarred perimeter of the Red Sea, as far as Quwait at the northernmost end of the Persian Gulf ; anywhere, in fact, where a clear channel in these waters gives easy access to a shelving beach and sheltered inlet : here the tall masts of dhows may be seen slanting this way or that in the various stages of careening and repair. For building, too, many of these shallow-water harbours are well known among the seafaring fraternity Yanbo, Jeddah, Djibouti, Assab, Bahrein, Muscat, and notably Calicut and Quwait. Occasionally it may happen that someone in a less-known haven may wish to have a dhow built : even Gwiyai, or Flamingo Bay, the little creek some four miles north of Port Sudan where for many years the Sudan's dhow traffic has been mainly directed, has more than once seen a dhow come into beingon its beach.


As a controversial writer,Sontag shows us in her gripping description Maryna's search for ideal self in the novel In America.This paper attempts to analyze Sontag's individuation in her writing and then it centers on the protagonist's self as well as her unremitting efforts to actualize the dream.Thus the paper may shed light on the writer's thought about self consciousness.


The major problem in the study area is the unlawful water abstractions for irrigation use. In South Africa, indications show that about 240 million m3/a of illegal water use is due to unauthorised withdrawals or violations of water use licenses. The status of water use for irrigation in the Orange-Senqu Basin also shows that insufficient information exists such that work needs to be done to understand the potential for increased efficiency of water use, taking into account issues pertaining to crop type, soil type and technological options. Studies like this one could also shed light on the potential impact of climate change on water use in the basin as this area may well experience significant impacts from rising temperatures and changing rainfall patterns. The processes of validation and verification will determine the extent of existing lawful water use. The use of remote sensing techniques (satellite, aerial photographs, etc.) could be employed to determine if the volume of water use registered by irrigators is accurate, i.e. valid and that the volume of water use registered is lawful (verification). Currently, ecological requirements for the river mouth are met through releases from Vanderkloof Dam and amount to just 290 million m3/a. However several recent studies including the Gesellschaft fur International Zusammenarbeit - Integrated Water Resources Management (GIZ – IWRM) study highlight that this is based on a fairly outdated methodology. The more recent Lower Orange Management study found a high level estimate of ecological requirements to be in order of 1 062 million m3/a.


The invention discloses a specially-designated editing method for DNA (deoxyribonucleic acid) molecules. The method includes the steps: taking a glass slide as an intermediate medium of a regulating device, taking a copper adhesive tape as an electrode board of the device, and respectively leading out a lead for connecting with a direct-current power supply on the upper surface and the lower surface of the electrode board by the aid of interaction of static electric field charges; diluting DNA molecule solution to a certain concentration by the aid of TE buffer, enabling the diluted DNA molecule solution to serve as experimental DNA solution, taking fresh stripped fluoride crystal mica sheets as a substrate, placing the fluoride crystal mica sheets at the center of the electrode board on the electric-field regulating device, dripping the prepared DNA solution onto the mica sheets, charging for the device in a voltage increasing manner, placing DNA molecule samples extended under voltage values on an AFM (atomic force microscope) system to image until straightened and orderly-dispersed DNA molecule images are acquired on the mica sheets, selecting simple-root DNA molecules, and performing specially-designated cutting for the DNA molecules by the aid of a constant-force cutting method and an enzyme cutting method. The editing method has good stability, and constant-force and enzyme cutting methods are achieved, so that the method is simple, convenient and rapid, high in base pertinence and high in efficiency.


In this report are described the fabrication and the characterization of a lithium-metal, polymer electrolyte battery using a manganese oxide-based cathode. The system operates at moderate temperatures (80-100°C). The work is focused on the determination of the properties of the polymer electrolyte-based cell in real systems at true operating conditions. The work was developed within ALPE, an Italian project devoted to the realization of lithium polymer batteries for electric vehicle applications.


In this paper a Wang shaped patch antenna has been designed for wireless communication systems application such as cellular telephone and radar for the frequency range between 0.7575GHz to 1.2121GHz. The maximum bandwidth, gain, return loss, directivity and efficiency of proposed antenna is 46.16%, 5.2dBi, -25dB, 7.60 dBi and 93% respectively. The antenna design offers high bandwidth, low profile which is feed by coaxial probe at 64.75mm, 60.135mm and height of the substrate thickness is 1.6mm.


The effects of prostaglandin E1 on systemic and coronary haemodynamics were studied in cats before and after acute coronary artery ligation. Myocardial blood flow was measured using a heat clearance technique. Before coronary artery ligation, PGE1 caused systemic arterial pressure and peripheral vascular resistance to decrease and heart rate to increase. There was no significant change in the right atrial pressure, pulmonary artery pressure, stroke volume, cardiac output, and external cardiac work. There was an increase in myocardial contractility (dp/dt max) and myocardial blood flow. After coronary artery ligation there were more pronounced decreases in the systemic arterial pressure and vascular resistance, with no increase in myocardial contractility and only slight increase in the blood flow in the ischaemic area of the myocardium.


Objective To determine free and total cortisol serum concentrations in the first 24 h after trauma and to evaluate the influence of traumatic brain injury (TBI) on their dynamics. Methods This prospective cohort study enrolled patients who had experienced multiple trauma and were admitted to a level 1 trauma centre. The patients were divided in two groups based on the presence of TBI according to clinical and radiological findings. Blood was collected initially as well as at 12 h and 24 h after the traumatic injury. Total cortisol, corticosteroid binding globulin (CBG) and free cortisol levels were determined. Results The study analysed data from 49 patients (36 males and 13 females) with a mean ± SD age of 45.0 ± 16.0 years. Of these, 36 presented with TBI and 13 had multiple injuries without TBI. Patients with TBI showed significantly lower concentrations of total cortisol and free cortisol compared with patients without TBI. Repeated measures analysis revealed different concentration dynamics in patients with TBI, with no increase in cortisol after trauma. Conclusion Multiple trauma patients with TBI are at risk of acute impaired cortisol secretion and show an attenuated stress response as early as 12 h after injury.


A DNA primary sequence is a string consisting of letters on an alphabet Ω = {a, c, g, t}. Based on all of the 2‐combinations of the set Ω, here the repetition is allowed, we transform a DNA primary sequence into a special sequence over a set with cardinality 10. With the 10‐letter sequence, we associate 10 nonnegative numerical sequences and then derive a 10‐component vector by means of a weighted pseudo‐entropy, which can reflect the information on elements of a sequence and, especially, the order relation among them. The new quantitative characterization of DNA sequences is sensitive to substitution of the string elements. The examination of the relationship among β‐globin genes of 15 species illustrates the utility of the proposed approach. © 2010 Wiley Periodicals, Inc. J Comput Chem, 2011


The Mossbauer effect of Coulomb-excited 57Fe implanted through vacuum into copper, silver and aluminum was studied at room temperature. From the derived Mossbauer parameters we conclude that the recoils are substituted into regular lattice sites of Cu and Ag within 10-7 s. A small line broadening in the case of Fe in Ag may reflect some radiation damage. For 57Fe implanted into A1 we tend to say that a large fraction of the excited recoils comes to rest in a split interstitial configuration while the other implanted impurity atoms are stopped on substitutional lattice sites.


Introduction: Impaired MCC contributes to the symptoms and pathophysiology of COPD. MCC from the large airways has been imaged in two dimensions and measured by Tracheal Mucus Velocity (TMV), and is reduced in patients with COPD (Morgan et al, ERJ 2004). Aim: To image MCC in the trachea in 3-D to accurately map mucus dynamics, as a prelude to assessment pharmacological intervention on TMV in COPD. Methods: 20 patients with mild-moderate COPD (mean FEV1=67%) participated. Patients were imaged after a 7-day washout of their LAMA and LABA, and on day 2 after a dose of Indacaterol. A droplet of 0.1mL radio-labelled albumin (Tc MAA) was injected through the crycothyroid membrane with the patient sitting at 45 degrees. Injection was followed immediately by a 15min acquisition under the gamma camera which captured lateral and AP images every 30 seconds. Frame by frame analysis was then used to visually assess movement. Results: Radio-label was successfully deposited down the length of the trachea in 39/40 studies. 38/39 traces cleared antegrade. Of these in 35 clearance was clearly in a right handed spiral, while in 3 the direction of spiral was indeterminate. In 27/39 clearance was in a continuous trail, while in 12 the mucus separated and re-coalesced as it cleared. Indacaterol did not effect the pattern mucous clearance. Two patients experienced mild bruising at the site of injection. Conclusion: Imaging of mucus clearance in two planes allows accurate mapping in three dimensions. This led to the novel finding that mucous clearance normally spirals as it moves up the trachea.


Matrix material containing sugars and / or sugar alcohols, for encapsulating solid or liquid substances, especially active and / or an acceptable aroma from pharmaceutically containing the matrix material pharmaceutical substances a substance, on cooling of the melt largely suppresses crystallization, and is present in an amount of 10 to 50, preferably 20 to 35% by weight, wherein the substance inhibiting the crystallization is the internal ester of a hydroxyacid especially glucono delta-lactone.


First, it cannot explain the differences among the writers—unless it is assumed that verbal differences indicate different events. In that case, one would have to say that Jesus was tempted by the devil twice, that the Lord's Supper was offered twice, and that Peter denied the Lord six to nine times! In fact, one might have to say that Christ was raised from the dead more than once if this were pressed!


Gone are the days when assessment was about simply grading children. It is now about learning and discovering where they go next, says Crispin Andrews


Traditional English teaching cannot get along well with the trend of English internationalization and globalization.How can we create an English language environment is the key for English learning.In recent years,with the introduction of some foreign films and the spread of Internet technology,original films offer a good language environment,along with the rich western culture for the English learners.However,how can we use the original film to create the language environment,to stimulate the learners' interests and to promote the learning effect is the question for every English teacher to think about.


The paper analyzes the characteristics of Zhejiang industrial clusters as well as the root for their demand on logistics development,on the basis of which,the influence and optimization effect of the clusters on regional logistics development are studied.


Modern precision pneumatic drills (1-500 kg/ha) used in the cultivation of high density crops such as winter cereals (up to 400 plants/m2) are very high performance equipment that triple the working width (up to 9m) and rates (up to 14 km/h) compared to those used fifteen years ago. Most of enterprises commercialize such devices using as cornerstone a central pneumatic distributor in combination with a large number of radial outlets (24-48). In spite of the unquestionable advantages of these devices with regard to more conventional gravitational distributors, the main drawback remains the lack of transversal uniformity which has proven to be fairly sensitive to seed size and shape, to slight air flow changes related to partial obstructions of outlets, elbows and grips in discharge outlets, or vibrations and inclinations of the central distributor, as well associated to inadequate maintenance of the machine by untrained operators. Moreover, the lack of behavior predictability derives in a certain discredit of the pneumatic procedure. This work proposes a theoretical-empirical methodology to analyze the pneumatic circuit and its interaction with a variety of seeds types to be delivered, and selected operational machinery settings, within the aim of elaborating a test protocol which combined with low cost instrumentation will serve a base for predictive maintenance. Experimental data gathered in static and dynamic tests performed by the authors on at least two different seeders together with published information available on technical papers will be reviewed and used for further discussion on reliable diagnosis procedures.


Qualitative characterization and quantitative analysis of 15 bioactive constituents in Jiweiling freeze-dried powder (JWL) have been achieved by reversed-phase high performance liquid chromatography coupled with tandem mass spectrometry, including five flavonoids and ten ginsenosides. Chromatographic separation was performed on an Agilent ZORBAX Eclipse XDB-C18 HPLC column, with gradient elution of 0.1% formic acid aqueous solution and acetonitrile as mobile phase. The compounds were detected in the negative ion mode with multiple reaction monitoring (MRM) using a triple quadrupole mass spectrometer equipped with an electrospray ionization interface. By using of this method, 15 bioactive components were unequivocally identified on the basis of their characteristic fragmentation patterns. All calibration curves showed good linearity (r2 > 0.998) within the test ranges. The LOD, LOQ, specificity, precision, and accuracy for the method were validated. The proposed method was successfully applied to analyze the quality of 12 batches of JWL. The results indicated that this analytical method was simple and suitable for the identification and quality assessment of JWL.


The protein encoded by TSPAN12 is a member of the tetraspanin family.The tetraspanin protein family contains 33 mamalian members.Most of these members are cell-surface proteins that are featured by specific conserved amino acids and specific structure,including 4 transmembrane hydrophobic domains.The proteins mediate signal transduction events that play a role in the regulation of cell development,activation,growth and motility.Its main binding partner is the ADAM 10 protein,and it also binds to the MT1-MMP metalloprotease protein,suggesting TSPAN 12 play an important role in tumor progression.

Key words:
TSPAN12 ;  ADAM10 ;  MT1-MMP ;  Invasion and metastasis


Summary The proportional counter is applied to the problem of determining the energy expenditure per ion-pair formed in argon, methane, ethylene, air, nitrogen, oxygen and carbon dioxide. Two different methods are applied. In the first the nearly homogeneous X-rays of Copper 64 are employed and the measurement of the number of disintegrations per minute occurring in a known fraction of the source is compared with the ion current through the same tube due to the whole source. Tritium gas is used likewise, in known relative amounts, to give rise to ion-currents and counting rates of easily measurable magnitudes. Hence the energy expenditure is obtained for the photo-electrons produced by Kα X-rays and for the slow β-rays of tritium (average energy=5·7 Kev). The advantages obtained by using slow β-rays in counters are stressed.


. Asymptotic results of two types are given for minimum norm cubatures, defined on a certain Hubert space of analytic functions. Cubatures with a high degree of precision are realized as the limits of minimum norm cubatures, and an algebraic approach for the determination of efficient rules is derived. Numerical methods and examples are also included.


An important capability for service robots working with humans in indoor environments is their ability to categorize the different places where they are located. In this paper we present an approach to categorize different areas in indoor environments using an RGB-D sensor like the Kinect camera. First, RGB images are transformed into grey scale images. Then, grey scale and depth images are transformed into histograms of local features that incorporate neighboring relations by applying local binary patterns and also a short version of this pattern. The feature vectors corresponding to grey scale and depth images are combined and categorized into different places using supervised classifiers like for example support vector machines. We apply this method to distinguish five different place categories and obtain high recognition rates. 1. は じ め に


The evolution of double jeopardy in India from a procedural criminal law to a constitutional privilege is traced in this paper. The paper would analyse judicial rulings on the scope and boundaries of the doctrine of double jeopardy in-depth and attempt to sensitize and educate readers who are unfamiliar with Indian laws about the regional variations in this nearly universal principle that a person should not be punished twice for the same crime.


While it seemed likely on paper that the Conservatives would have reclaimed Eastleigh at the byelection, in practice it was the Liberal Democrat campaign on the doorsteps which secured their victory. Mark Garnett argues that this shows that local factors can still prevail within British politics but also points to UKIP's success as testifying to the power of symbolism.


Background: Youth alcohol and drug misuse has multiple long-term consequences. Suggestions to reduce the frequency of this include combining Screening, Brief Interventions, and Referral to Treatment (SBIRT). However, SBIRT has not been studied widely in children and youth.
Methods: The present observational study was part of a larger school-based intervention program, termed Empowering a Multimodal Pathway towards Healthy Youth (EMPATHY), whose primary goal was to reduce depression, anxiety, and suicidal thinking in youth. A secondary goal was to determine if the EMPATHY program, which utilizes all aspects of SBIRT, might also decrease alcohol and substance abuse in children and youth. Here we examine data from the 6 items of the CRAFFT scale which was specifically designed for youth assessment, and a score of ≥ 2 indicates risk of substance abuse. We examined CRAFFT scores from 6,227 students who completed at least one assessment, either at Baseline, 3 months, 7 months, and 15 months. We also report on CRAFFT scores in the 1,884 students who completed CRAFFT assessments at all 4 times.
Findings: We found that, as expected, rates of substance abuse increase with age. The EMPATHY program, which entails a version of SBIRT, led to a significant reduction in the total percentage of students who scored ≥ 2 over time, decreasing from 14% at Baseline to 7% at the 15 month follow-up. This occurred in all grades, specifically at Baseline 31% of Grade 12 students scored ≥ 2, but this decreased to 20% at 15 months, while reductions in Grade 11 were from 24% at Baseline to 15% at 15 months.
Conclusions: The findings from this large long-term program may indicate good utility for an SBIRT approach in children and youth. This may help provide an effective pathway to minimizing future use of alcohol and drugs in children and youth; however, more specific randomized controlled studies are needed to confirm these promising, but preliminary, findings.


The Westernizationers started the modem fashion of studying abroad for military purposes. This unrefined education sowed seeds of modernism in China which strengthened the cultural communication between China and other countries and acted as one of the key promoting elements in the social changes of the late Qing Dynasty. Lengthwise, studying abroad in Westernization Movement broke through Chinese traditional education. Crosswise, this education accorded with the world development trend and improved human cultural development and is an indispensable part of the modern national education system.


The national Turning Point [1] program was launched by the Robert Wood Johnson Foundation and the W. K. Kellogg Foundation with a vision to transform and strengthen the public health system in the United States by promoting community-based and collaborative processes. In Arizona, three projects were selected for funding by the national Turning Point program, including the only project nationwide that envisioned public libraries as part of the solution.

AZHealthInfo, a state-focused health information Web resource developed for public health consumers and communities in Arizona, grew out of this proposal [2]. The initiative described a plan "to build community leadership through training and information dissemination … to establish centers for public health in public libraries, public health departments and tribal service centers" [3]. It was modeled on an earlier program to develop Economic Development Information Centers (EDIC) [4, 5] in public libraries around the state to support the local business community and improve the economic climate.


This study was conducted to know the effort or strategy of principal in improving the character of student discipline. The research method used a qualitative approach. The technique of data collected was by interview, observation, and documentation study. Informants in this study consisted of principals, vice principals, counseling teachers, classroom teachers, school security officers, and students. In improving the character education of student discipline, the results of the research indicate that the principal's effort or strategy by implementing the doctrine program enforced in habituation. Activity habituation through activities: cheerful morning, a congregation of praying Dhuha, tadarus Al-Quran, literation, and memorization of "Limas' doctrine. This result can be a school reference, primarily a faith-based school, to enforce discipline as a character's identity of students.


The novel "Demons" presents a polyphony of the characters' opinions, however, the revolutionary idea of Peter Verkhovensky, whose anti-Christian essence is revealed by Dostoevsky, is aggressively dominant. Revolutionary Machiavellianism finds its expression in the plot of the novel, which moves due to the active efforts of Pyotr Stepanovich, and the exposure of the hero's demonic idea sets its anti-nihilistic genre vector. The narrative strategies of the novel are defined both through Verkhovensky's ultimate goal — the "shock" and "decomposition" of the society's spiritual and moral foundations to lead it to a revolution — and through the presentation of the hero's communicative tactics on the way to this goal. Pyotr Verkhovensky uses the well-known "recipes" of the political "kitchen:" he agitates, propagandizes, intrigues, incites, tempts with future blessings, etc. The main mechanism of these acts is the psychological impact phenomenon. Precisely in view of this phenomenon it is explained how "the purest heart and the simplest people" can be turned into "demons." Verkhovensky skillfully guesses the others' mental structure and moral demands, studies the "living science of people," as a result of which he develops a whole system of verbal and non-verbal methods of psychological influence, which allows him to influence people of different social status, characters and aspirations. The use of psychological influence methods can be observed in his dialogues and targeted monologues, non-verbal methods of psychological influence are expressed through gestures, looks, tone of voice, body position, gait, etc. Various methods of psychological influence of Pyotr Verkhovensky are correlated with a number of motifs with a negative connotation: flattery, hypocrisy, fear, threat, denunciation. There is a connection between the artistic embodiment of the principles of Pyotr Verkhovensky's revolutionary tactics and the provisions of the revolutionary S. G. Nechaev, which were set forth in the Catechism of a Revolutionary (1869) that lent Dostoevsky his character's ethical attitudes, the intention to commit a crime and the generally demonic spirit of the theses he presents. Consideration of the means of psychological influence through the analysis of the speech and behavior of Pyotr Verkhovensky not only allows to correlate his thoughts with the ideological basis of this historical document, but also helps in a holistic understanding of Dostoevsky's novel.


Epoxy resin is one of the most used resins for obtaining composites and coatings. Its properties have been modified using many materials, mainly based on nanotechnology, such as clays and polyhedral oligomeric silsesquioxanes (POSS). POSS may increase thermal and mechanical resistance and hydrophobicity of the epoxy resin. This study aims at characterizing epoxy nanocomposites, using two distinct resins (DGEBA and DGEBF) and an addition of glycidylisobutyl-POSS in contents of 2.5% and 5% (w/w), through X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA) and dynamic mechanical analysis (DMA). Samples showed an amorphous halo due to the epoxy resin and a characteristic peak of POSS. TGA results showed a greater residual mass in DGEBF systems due to its wider formation of crosslinks. FTIR spectra demonstrated a higher amplitude of the hydroxyl band in DGEBF 5% system, which may affect its hydrophilic behavior because of the molecular mobility and resin weight reduction. DMA results showed that DGEBA systems are more flexible than DGEBF.