The rabbit-ear chamber provides a convenient method for studying small blood vessels at high magnifications and for long periods of time. This technique had been employed to study the course of tuberculous infection,l the focal reaction, and serum sickness.2 This technique has also revealed, a t least in part, the manner in which cortisone modifies the inflammatory response of tissues to infection3 and to hypersensitivity states:, The technique and the tissue changes described here were illustrated by a Kodachrome motion picture The first portion of the film illustrates the mechanical construction of the chamber and the method of making observations. The chamber itself is made of lucite6 and consists of a base plate with a raised central observation table, a mica cover slip, and a lucite cover-slip-retaining ring. The chamber is inserted into the pinna of the rabbit with a strictly aseptic technique. At the time the chamber is inserted, a clot is formed on the central observation table and, in the ensuing three to four weeks, blood vessels grow into this clot and transform it into a thin vascularized layer of connective tissue. The normal vascular pattern in such a chamber is composed of arterioles, venules, and capillaries supported by an undifferentiated layer of connective tissue. The arterioles have a well-developed muscular wall, a highly refractile endothelium, and a narrow uniform bore. The muscular wall is actively contractile, and arterioles periodically show complete constriction for short periods of time. The venules are wide channels, not of uniform diameter, and tend to be somewhat tortuous. The capillaries have only a thin endothelial wall, a narrow diameter, and are intermittently closed off by precapillary sphincters.


Acoustic droplet vaporization (ADV), a process whereby liquid droplets are vaporized into gas bubbles using ultrasound, has been studied in vivo as a method to generate vascular occlusion. This work focuses on the development of a double emulsion that releases a chemical embolic agent, thrombin, upon ADV — thereby potentially extending the duration of ADV-induced occlusion. Micron-sized, double emulsions were formulated, using a two-step process, with the following structure: water-in-perfluoropentane-in-water (W1/PFP/W2). Thrombin was contained in the W1 phase. Emulsions produced using low shear techniques during the second emulsification step yielded the highest thrombin encapsulation (> 95%). The ability of ADV to release the thrombin was tested by exposing the emulsions to acoustic pulses from a 3.5 MHz single-element transducer (4.7 MPa peak rarefactional pressure) while in an OptiCell™ chamber. ADV caused the activated clotting time (ACT) of citrated blood to decrease, in a statistically significant manner (p < 0.01), compared to blood incubated with emulsions not exposed to ultrasound.


Using the Content Analysis method and the official Sustainability Reports on the corporate websites, this research seeks to verify how much of what is required of the Global Reporting Initiative (GRI) core indicators, in its most recent version (G4) has been met. The measuring tool used was the GAPIE (that represents the Degree of Full Adhesion) and the GEE (Degree of Effective Evidence), compared to previous years. All the companies of electricity from South America that had published, in 2017, their Sustainability Reports for 2016 in the G4 version and presented the index of GRI indicators on these were part of the research. It was found that companies, in general, still perform poorly quality of social and environmental information compared to the previous one standard report (G3). The worst area was in the social sphere, which addresses sensitive issues such as corruption and benefits to employees, as well as the communication capacity in which socially established ownerships in the communities present. In addition, mostly companies preferred to present as much as possible their economic indicators, to the detriment of the other questions.


The nano-size Pb(Ⅱ)-phthalate was prepared with potassium phthalate and Pb(Ac)_2·3H_2O by ultrasonic liquid dispersion deposition method. The effects of reaction temperature,reactant concentration,dispersant quantity on particle size of Pb(Ⅱ)-phthalate were studied. The nano Pb(Ⅱ)-phthalate with particle size of 43 nm was obtained at 10 ℃ with concentration of 0.4 mol·L -1,and dispersant quantity of 8%. Moreover,the catalysis of nano-size Pb(Ⅱ)-phthalate for double-base propellant (DB propellant) was studied. It is found that nano Pb(Ⅱ)-phthalate increases burning rate of DB propellant at 2-22 MPa and make DB propellant emerge mesa effect at 6-10 MPa. Compared with common Pb(Ⅱ)-phthalate,nano Pb(Ⅱ)-phthalate enabled the burning rate of propellant to be higher than that of propellant including common Pb(Ⅱ)-phthalate,and its pressure exponent is lower at 6-10 MPa.


PURPOSE: A thermo-hygrostat using a cooling/dehumidifying heat recovery technology is provided to save energy for cooling, dehumidification, and reheating at the same time, thereby reducing obstacles of the installation space by efficiently forming an air flow path. CONSTITUTION: A thermo-hygrostat(10) using a cooling/dehumidifying heat recovery technology comprises blowers(20,70), a heat exchanger(30), cooling and heating coils(40,50), and a humidifier(60). The heat exchanger and cooling coil are installed in a supporting frame(F) where an air path(10A) is formed by a partitioning plate(80). The cooling coil is horizontally installed in the lower part of the heat exchanger. The passed air through the heat exchanger is cooled by passing through the cooling coil and flowed into the heat exchanger again. The re-flowed air into the heat exchanger is heat exchanged with the air flowed from indoor and discharged to the indoor through a path. Intake and discharge holes of the heat exchanger are formed to have the path.


Significance Precise cell division is crucial for all cellular life. In the pneumococcus, which kills more than a million people annually, the protein MapZ was recently identified as a marker for the division site. By developing a suite of tools, including a chromosome labeling system and CRISPR/Cas9-based perturbation of chromosome segregation, we mapped the pneumococcal cell cycle in detail. We show that MapZ is not involved in division site selection but is important for setting the correct angle of the division plane. Importantly, we demonstrate that the pneumococcus has a unique chromosomal organization and that timely replication and segregation of the chromosomal origin to the future cell division site is a key determinant for correct positioning of cell division proteins. Accurate spatial and temporal positioning of the tubulin-like protein FtsZ is key for proper bacterial cell division. Streptococcus pneumoniae (pneumococcus) is an oval-shaped, symmetrically dividing opportunistic human pathogen lacking the canonical systems for division site control (nucleoid occlusion and the Min-system). Recently, the early division protein MapZ was identified and implicated in pneumococcal division site selection. We show that MapZ is important for proper division plane selection; thus, the question remains as to what drives pneumococcal division site selection. By mapping the cell cycle in detail, we show that directly after replication both chromosomal origin regions localize to the future cell division sites, before FtsZ. Interestingly, Z-ring formation occurs coincidently with initiation of DNA replication. Perturbing the longitudinal chromosomal organization by mutating the condensin SMC, by CRISPR/Cas9-mediated chromosome cutting, or by poisoning DNA decatenation resulted in mistiming of MapZ and FtsZ positioning and subsequent cell elongation. Together, we demonstrate an intimate relationship between DNA replication, chromosome segregation, and division site selection in the pneumococcus, providing a simple way to ensure equally sized daughter cells.


Cloud and rain behavior are the main issues to be considered in the analysis of flood events from aspects of atmospheric science. To analyze the spatiotemporal variation analysis of clouds and rain, black body temperature (TBB) data from the IR1 channel of the Himawari-8 satellite and rainfall data of GPM_3IMERGHHL v03, which has a spatial resolution in 0.01° and temporal grids every 10 minutes, and in 0.1° and temporal grid every 30 minutes were used. The purpose of this research is to know the behavior, especially the spatial and temporal variation, of cloud and rain that happened above Tangerang area before, shortly and after flood event on November 13, 2016. The result show that cloud with temperature of TBB <220 K located within the 105.5° - 108.5° E range that occurs within the timeframe of 09:00Z Saturday 12th November 2016 to Sunday 13th November 2016 at 21: 30 UTC as a phenomenon that contributes greatly to the flood incident in the area under review and related to the incidence of rain in the regional range and time of 6.05° - 6.30° S; 106.45° - 106.70° E at 10:00 UTC until 21:30 UTC on Sunday November 13, 2016.


Once diagnosed as "cell paucity"or "atypia" by the cytospin (CS) preparation, this CS preparation does not secure a precise diagnosis by repeated testing alone. Although the ThinPrep (TP) preparation is acknowledged to show increased cellularity, performing the screening tests for the cases that have enough cellularity, according to CS, raises issues for the cost-effectiveness. To obtain a more precise diagnosis through increasing the cellularity by performing TP, we selected the cases that were diagnosed as "cell paucity" or "atypia" by CS, but they required a more precise diagnosis, and the samples were processed via both CS and TP to compare the results. 11 patients diagnosed as "cell paucity" and 22 patients diagnosed as "atypia" by CS participated in this study. When the detection rate of atypical cells in both preparations with repeated urine cytology was compared, the overall detection rate of TP (16cases, 48.5%) was superior than that of CS (11cases, 33.3%), with statistical significance. The cellularity of both preparations was compared on repeated urine cytology; the general cellularity of TP (29cases, 87.9%) was higher than that of CS (20cases, 60.6%), but there was no statistical significance. Particularly, we repeated the TP for the 1 case that was diagnosed as "atypia" and we performed polyoma virus immunohistochemical staining, which confirmed polyoma virus. In conclusion, we can avoid obtaining negative diagnosis from cases with uncertain "atypia" or "cell paucity" by performing repeated TP testing.


Article is devoted a problem of increase of efficiency of performance of attacking blow by volleyball players of 15-17 years. The author selects blocks of the exercises directed on perfection of a rhythm of running start at performance of attacking blow by volleyball players of 15-17 years and checks their efficiency.


where n is an integer, then every solution of (1) has at least n zeros in [a, b]. The number 9/8 cannot be replaced by a smaller one. A theorem similar to this, but with more restrictive hypotheses, has been proved by Makai [5]. Related theorems have been proved by a number of authors, back as far as Liouville. More recent examples are given in the references. The proof depends on three lemmas. Lemma 1. If the equation (3) y" + q(x)y = 0, where q(x) is continuous, has a solution with consecutive zeros at x = c and x = d, and if


Introduction Land degradation has been identified as severe envi ronmental problem in Ethiopia, especially since the early 1970s (Gebremedhin, 1998 ). Betru (2003) reported that the country losses around 2 billion tons of fertile soi l subsequently losses 2% of the annual grain production, which is roughly equivalent to 12 0, 000 tons of cereal per annum (Mesfin, 2004). Despite this fact, Ethiopia has bee n in continuous struggle to increase agricultural production, reduce poverty and ensure sustainable use of the natural resources, especially since the early 1990s. Increa sing population pressure on an already degrading land resource has rendered the struggle e ven tougher. Eicher (1994) suggests that increases in agricultural production need to c ome primarily from improvements in land productivity since the land frontier are shrin king. However, a significant increase in agricultural productivity can not be attained if th e land resource base continues to be degraded. Hence, ensuring sustainable land manageme nt is a matter of critical importance for agricultural growth in Ethiopia. A number of pr ograms and projects for sustainable land management (SLM) have been implemented since t he arly 1970s. However, natural resources conservation interventions were primarily technology oriented, beneficiaries had less stake in decision making and not linked wi th activities generating better income in a short period of time to the community. As a re sult, the natural resources conservation efforts were less successful. Thus, IPMS project in collaboration with other stakeholders studied the effect of linking natural resources con servation interventions with market oriented commodity development on the sustainable l and management in four districts of Ethiopia. This paper presents results of the analys is of the approach of linking market oriented commodity development with natural resourc e development.


This study investigates the relationship between NGO partner's resources and CSR program performance because recent research trend does not fully explain the reality of CSR by ignoring the increasing cross-sector alliances between firms and NGOs for CSR. This article develops a research model based on resource-based view and empirically examines the effects of NGO partner's resources on CSR program performance. In addition, this article explores the role of resource complementarity between firms and NGOs in implementing CSR. We conducted face-to-face surveys with CSR staff from 21 corporations and had additional interviews with 17 CSR staff. Finally, we obtained a sample of 104 CSR programs and tested the hypotheses with regression analysis. Results indicate that resources of NGO partners, especially knowledge and reputation, significantly affect CSR program performance. The more knowledge NGO partners possess, the greater CSR program performance firms achieve. Reputation of NGO partners is also positively related with CSR performance. This study supports that knowledge complementarity plays a moderating role in the relationship between NGO partner's resources and CSR program performance. Our findings reveal more clearer picture on CSR activities in two ways. First, this study explains the motivation of cross-sector alliances in the context of CSR from firms' perspective. Second, this paper suggests that more strategic approach to partners' resources should be required for successful cross-sector alliances, specially in cooperative partner selection processes.


so many territories and is a modular piece with parts for clarinet, cello, piano and accordion. Each score has a 8×8 grid of cells, each containing a short sound. The players work their way independently across the grids from the top left corner to the bottom right, moving either up, down, left or right and following a series of rules. Each cell is a permutation of up to four parameters (two pitches, dynamics and articulation), controlled by a mutually orthogonal latin square. I discovered these through George Perec who used them in Life: A User's Manual. Each cell is a unique permutation of the four parameters, such that no pair of parameters is repeated in combination. The title comes from a line in a Bon Iver song.

First performed: Plus Minus Ensemble, Performance Space, City University, London, 08.04.14


Purpose
Transformation and involvement from every organizational function are essential in creating a diverse and inclusive workplace. The paper explores the role of training and development (T&D) interventions in building a diverse and inclusive workplace.

Design/methodology/approach
Through the review of existing research studies, the authors report and discuss how T&D function supports fostering a diversity and inclusion (D&I) mindset in the workplace and propose an organizational schema that facilitates the systematic design and implementation of T&D interventions for D&I.

Findings
Based on the literature an organizational schema was developed which indicated that to foster a D&I mindset in the workplace, it is important that diversity training is designed after considering established diversity theories. Further diversity training can be conducted in two phases, where phase 1 would focus on awareness training and phase 2 on skill training. This would lead to an increase in employee competency development including knowledge, skills, behavior, and a positive attitude toward a D&I mindset.

Practical implications
HR and training managers can benefit from the paper indicating that for achieving effective results from diversity training, it must draw insights from established diversity theories. Through the organizational schema discussed in the paper, organizations can minimize the negative attitude and behavior that emerge from social categorization with the help of systematic T&D where employees are made self-aware of their prejudice and discrimination and further equipped with relevant skills to manage diversity.

Social implications
A positive mindset incorporated by employees at a workplace with reference to Diversity & Inclusion through structured D& I training can percolate beneficially to the society as a whole.

Originality/value
The study is a rare one that explores the impact of T&D on D&I. The novelty of the research lies in the organizational schema presented in the study exploring how HR practitioners must systematically design T&D for D&I combining both theory and practice to achieve long-term organizational diversity management objectives.


The invention discloses an automatic testing and early-warning device for track plate displacement. A formwork is arranged between a track plate and a concrete base. The track plate is provided with a grouting hole and an observation hole. A magnetic gauge stand is fixed to the side face of the formwork, a universal support arm is arranged on the magnetic gauge stand, a displacement detection device is fixed to the end of the universal support arm, a probe of the displacement detection device makes perpendicular contact with the top face and/or the side face of the track plate, and the displacement detection device is connected with a tester host through a connecting wire. The tester host is provided with a recording device, a display device and a printing device, and further provided with an early-warning sound or lamplight prompt device. The automatic testing and early-warning device can automatically detect the floating amount or sinking amount of the track plate during filled layer grouting, is convenient to use, easy to operate and easy and convenient to install, data are accurate and objective, the detection result can be automatically displayed, early-warned, printed and stored, the labor intensity of plate type ballastless track filling layer pouring construction staff is lowered, and efficiency is improved.


This article sample that Colombia seems to have levels of minimum wage and labor unmannerliness greater than the hoped ones in agreement with its entrance per capita, although is not between the countries of "maxi minimum wages". The shown descriptive empirical evidence does not seem to support the traditional approach on the relation between minimum wage and unmannerliness. This means that multilateral governments, analysts and organizations would have to be prudent when they recommend for the countries developing reductions in the minimum wage with the purpose of improving the entrance of the informal workers. From great importance it turns out to modify the against-cyclical policy of implemented minimum wage in the analyzed period, judging by the behavior of his relative levels. Finally, the policy of minimum wage in Colombia seems to be changing its objective, due to the enterprise strategy to eliminate the decentralized collective negotiation.


The optimum time of producing intracellular polysaccharides (IPS) was studied to be 84 h in this paper. The optimum extraction conditions of crude IPS were: 90 ℃, 3 h, 2 times, damaging cell wall for 12 min. The proteins of IPS were removed high efficiency by sevage and CFC-113. Two kinds of IPS were obtained by Sephadex G75. Paper chromatography and Sephadex G200 showed that IPS I and IPS II were pure. Then the components of both IPS were considered by thin-layer chromatography, and they were mannose, glucose and rhamnose. Finally, the structures of the polysaccharides were analyzed preliminarily by infra-red spectrum. The structures of the two IPS had little difference.


Key Points Question How did American Indian youth who live on or near reservations experience the COVID-19 pandemic? Findings This cross-sectional study among 2559 American Indian students in grades 6 through 12 found that approximately 14% of the sample reported having had a test result positive for SARS-CoV-2 infection, a higher rate than for all cases nationally and for children nationally, and three-quarters of the sample reported someone close contracting COVID-19, while more than one-quarter reported someone close dying from COVID-19. Regarding perceived psychosocial impacts, COVID-19 was associated with strained friend relationships, lower school engagement, and less social connectedness, although more than 60% of students reported feeling no change or a decrease in negative emotions, such as sadness and anxiety. Meaning These findings suggest that although COVID-19 mortality and morbidity rates were high on American Indian reservations, psychosocial impacts were complex and many students were resilient in the face of the pandemic.


PURPOSE: Provided is a-galactosidase A and treatment for a-galactosidase A deficiency CONSTITUTION: A therapeutic method whereby an individual suspected of having an alpha-galactosidase A deficiency, such as Fabry disease, is treated either with (1) human cells that have been genetically modified to over express and secrete human alpha -gal A, or (2) purified human alpha -gal A obtained from cultured, genetically modified human cells


Popular discussions of the internal management of the U.S. House of Representatives in the present era generally give great weight to the ubiquity and arbitrariness of the seniority system as a significant determinant of outcomes there. Careful attention to the scholarly literature, however, should long since have modified this view. For it appears that except for relatively unimportant matters such as the allocation of office space on Capitol Hill, the criterion of seniority is generally intermingled in House decision-making with a great many other crite ria of choice, and the business of choosing is not automatic, but remains in the hands of persons having some considerable discretion. This, apparently, is the case with respect to such decisions as the allocation of Capitol Hill patronage, the initial assignment of Representatives to committees, the distribution of responsibilities within committees, and the choice of party leaders. The one important area in which seniority seems to play a role of overwhelming significance is in the matter of succession to the chairmanship of committees; this is in turn governed by the custom (not a formal rule) of seniority that guarantees members reappointment to committees at the opening of each new Congress, in rank order of committee service. It is the growth of this method of selecting committee chairmen in the House that is the subject of this paper.


The problem of communicating one bit over a memoryless Gaussian channel with an energy constraint is discussed. It is assumed that the channel is allowed to be used only two times. An ideal feedback channel is also supposed available. The optimal feedback strategy and the bit-error probability are derived. It is shown that feedback gives a significant performance gain and that the optimal strategy is discontinuous. It is also shown that most of the performance increase can be obtained even with a one-bit feedback channel.


Objective: Patients affected by multiple sclerosis show a progressive retinal nerve fiber layer (RNFL) thinning which is correlated to disease activity and cerebral atrophy. It is still unknown if progressive retinal thinning occurs in NMOSD. Background: To compare retinal axonal damage evolution in multiple sclerosis and neuromyelitis optica spectrum disorder, in order to highlight differences in terms of neurodegeneration. Design/Methods: 65 patients, with or without previous optic neuritis (ON), have been included in the study; 45 affected by multiple sclerosis and 20 by NMOSD. All patients underwent neurologic and neurophysiologic evaluation with OCT at baseline and after an average time of 2 years and 3 months; during this period clinical-radiologic disease activity was monitored. Results: The reduction of retinal thickness was greater in MS patients (−0,45 ± 0,75 μm/year) than NMOSD patients (−0,16 ± 0,67μm/year). Disease activity is the main determinant of axonal neurodegeneration, in MS patients (−0,72 ± 0,78 μm/year in MS-EDA vs −0,18 ± 0,64 μm/year in MS-NEDA; p = 0,026), while the presence of a previous ON has a lower impact. Focusing on eyes without previous optic neuritis, in NMOSD patients retinal thinning (−0,38 ± 0,53 μm/year) was not significatively different from that occurring in MS-NEDA patients (−0,17 ± 0,70 μm/year). A significative correlation has been observed, only in eyes without previous optic neurits, between retinal nerve fiber layer (RNFL) measured at baseline evaluation and the extent of RNFL thinning year rate (ρ = 0,014, r = −0,394). Conclusions: In NMOSD patients retinal thinning is lower than the one showed by MS patients with evidence of disease activity, and is not significatively different from the one showed by MS patients without evidence of disease activity. Disclosure: Dr. Leocani has nothing to disclose. Dr. Ratti has nothing to disclose. Dr. pisa has nothing to disclose. Dr. Guerrieri has nothing to disclose. Dr. Radaelli has received compensation for serving on the Board of Directors of Has received travel support from Merck Serono, Sanofi and Teva and honoraria for speaking from Teva and Sanofi. Dr. Moiola has received personal compensation for consulting, serving on a scientific advisory board, speaking, or other activities with Sanofi-Genzyme, Novartis, Teva, Merck-Serono, Biogen, Roche, Excemed. Dr. Martinelli has nothing to disclose. Dr. Comi has nothing to disclose.


Multi–agent systems can be considered as a part of distributed artificial intelligence approaches. They are particularly characterised by emerging global properties which stem from combinations of local interaction between individual pro–active elements called agents. Multi–agent systems have already been used in a wide range of applications but few applications integrate interaction with external devices and/or human beings. This paper presents a multi–agent–based application aimed, at producing emergent paintings based on both internal classical interaction and external triggering devices, such as music/sounds sources and motion captured by accelerometer sensors. The application results are computer generated paintings which can be classified as cyberart. The main challenge of this work is to obtain pertinent emergent paintings in relation with external trigger specificities.


In the network of information, changes of information transmission mechanism lead to difficulties and developments of judicial quantification of transmission conducts. The most typical development of person-time criteria is actual clicking times which reflect actual request times of network files and whose direction is to be transferred to viewing times and be combined with files' number to form new criteria. This experience of clicking times should be extended to re-sending times and responding times and downloading times should be introduced.


ABSTRACT Background Biliary diversion (BD) is indicated in progressive familial intrahepatic cholestasis (PFIC) with refractory pruritus. Three types-partial external biliary drainage (PEBD), partial internal biliary drainage (PIBD), and ileal exclusion (IE) are described, with no consensus about the relative efficacy of these procedures. Methods PubMed, Scopus, and Google Scholar were searched for publications on PFIC and BD. Improvement in pruritus, serum bile acid (BA), and need for liver transplantation (LT) were compared between the various BD procedures Results 25 studies [424 children (PEBD–301, PIBD–93, IE–30)] were included. Pruritus resolved in 59.5% [PIBD:72% (95%CI 43–96%), PEBD:57% (95%CI 43–71%) and IE:48% (95%CI 14–82%)] cases. Significant overlap in confidence intervals indicated no significant differences. Absolute decrease in BA (AUROC–0.72) and bilirubin (AUROC–0.69) discriminated responders and non-responders. Eventually, 27% required LT: PIBD 10.7%, PEBD32%, IE 27%. The post-operative BA (AUROC-0.9) and bilirubin (AUROC-0.85) determined need for LT. Complications were commoner in PEBD than PIBD (38% vs 21.8%: p=0.02). Conclusion 59.5% children have pruritus relief after BD and 27% need LT. PIBD has lower complications and LT requirement than PEBD. However, this requires cautious interpretation as the 2 groups differed in PFIC type and follow-up duration.


Recent research suggests that, in some situations, numeric information may lack the 'evaluability' of visual representations of the same data. In such cases, reliance upon numeric information exacerbates tendencies for survey respondents to rely upon heuristics rather than their underlying preferences in formulating responses. Adapting such insights to the field of non-market valuation, for certain environmental goods, information on increases or decreases in the numeric levels of an attributes may trigger reliance upon the loss aversion heuristic, leading to an exacerbation of the well know gains/loss asymmetry problem (Horowitz and McConnell, 2002). A split sample choice experiment (CE) is described in which standard approaches to conveying a land use change scenario (relying principally on numeric information) are contrasted with an alternative treatment in which objectively identical information is presented in visual form via virtual reality (VR) visualisations. A third treatment combines both formats. Results show that the gains/loss asymmetry is roughly twice as strong under a conventional numeric CE design than in the presence of visual information. The combined VRCE methodology developed in the paper therefore significantly ameliorates this pervasive anomaly and, we contend, represents an exciting prospect for the incorporation of complex real world environments within economic analyses.


In this work, we simulated the atomic structure of liquid iron and iron–carbon alloys by means of ab initio molecular dynamics. Voronoi analysis was used to highlight changes in the close environments of Fe atoms as carbon concentration in the melt increases. We have found, that even high concentrations of carbon do not affect short–range atomic order of iron atoms — it remains effectively the same as in pure iron melts.


This project focused on limited validation of the Richardson number (Ri) as a tool to forecast clear air turbulence (CAT) at the flight levels of most commercial and military aircraft. The Richardson number in this study was derived based upon ten flights over the United States in 1995. Airborne turbulence observations were taken by the principal author and received from other aircraft in the flight profile area. The results, while not representing an all encompassing case study, none the less illustrate the potential for Ri as a useful tool in operational forecasting of CAT. Values of Ri near four, rather than the theorized values less than one, correlated to higher possibilities for turbulence. The critical value of Ri for forecasting CAT could be further refined through more data from additional flights. There is also a need for more accurate aircraft instrumentation and a denser radiosonde and wind profiler network.


Ann Bishop was an eminent protozoologist and parasitologist who spent almost her entire career in Cambridge where she was a Fellow of Girton College for nearly 60 years. Her main work was concerned with the development of drug resistance in the protozoan parasites that cause the disease malaria, still among the most important agents of mortality in the world today.


This study was conducted to investigate the pathoprevalence of different infectious diseases of goat at Sadar upazilla of Dinajpur district in Bangladesh. Infectious cases were recorded with respect to breed, sex, age and season from Upazilla Veterinary Hospital and District Veterinary Hospital, Sadar, Dinajpur during July, 2014 to June, 2015 and diagnosis was made on the basis of clinical history, clinical examinations and common laboratory techniques with histopathological examination. A total of 2139 infectious diseases were founded and categorized by the causal agents where the highest prevalence was observed in mixed infectious diseases (46.06%) followed by viral diseases (28.93%), internal parasitic diseases (9.77%), external parasitic diseases (8.42%), bacterial diseases (3.00%), protozoal diseases (2.01%) and lowest was in fungal diseases (1.83%). The prevalence of infectious disease was significantly higher at Jamunapari (55.12%) than Black Bengal (44.88%). Female goats were more susceptible (54.32%) than male (45.68%). The prevalence was varied according to age and highest was in G-1 (45.48%) followed by G-2 (36.48%) and G-3 (17.68%). Summer season (33.60%) was common for infections followed by winter (33.51%) and rainy (32.89%). Most of the internal lesions were produced by the endoparasitic infections which were examined microscopically. These results indicate that, the prevalence of various infectious diseases in the goats was higher at Sadar, Dinajpur thus, there is a need for an appropriate control measures in order to prevent and minimize the loss caused by such diseases and this study may help to develop strategies against the infectious diseases of goat. Asian J. Med. Biol. Res. June 2017, 3(2): 254-266


A transverse bunched beam instability has been observed over the past few years in the KEK booster synchrotron, and the kicker magnet for the fast beam extraction has been thought to be responsible for this instability. To check this supposition, the instability was observed quantitatively using a spectrum analyzer and its growth rate was compared with calculations assuming various termination conditions at the feeding end of the coaxial cable of the kicker. The variation of the growth rate with time for a realistic case is well explained by the reflection of the current induced in the kicker at the feeding end of the cable.


This volume contains the proceedings of the symposium `A Stellar Journey: A symposium in celebration of Bengt Gustafsson's 65th birthday' held at Gustavianum in Uppsala, Sweden, on 23--27 June 2008. We sincerely thank all the participants who got their contributions to us despite a quite demanding deadline, enabling us to produce this festschrift for Bengt in good time following the conference. We believe these proceedings represent a valuable snapshot of a broad range of topics in modern stellar physics. The organisation of this symposium would not have been possible without generous support from the Swedish Research Council (Vetenskapsr∠det). We are also very thankful to the Uppsala University Physics Section and the Department of Physics and Astronomy for their financial and logistic support.


Qatar is facing unprecedented development both inland and in its surrounding waters. While the natural environment is not yet fully characterized, there is a need for managers to have an accurate overview of it as a decision making tool and a baseline study for monitoring the future changes. Remote sensing techniques are cost effective in their ability to cover great areas and provide information in a time and cost efficient manner. Development of new sensors such as the WorldView2 satellite and airborne hyperspectral sensors provides highly accurate data including habitat, and superficial soil characterizations. Finer scale techniques such as acoustic surveys can be deployed to compliment study areas of particular interest. Finally, data have to be verified and validated by visual field observations. Implementation of these new techniques for producing a large-scale geographic information system data set for Qatar would highly improve the current knowledge and provide a powerful decision making tool for ...


because of his large fortune, his net creditor position, and his more cautious approach to western investment. Both men showed considerable flexibility in working with their debtors during the difficult times. Two chapters examine Isaac Bronson's interest in bank theory and bank reform along with his monitoring of state activities with respect to laws dealing with assessments, tax collections, and mortgage laws. His primary interest was to protect the interests of absentee landlords and creditors, but he recognized the adverse impact laws unfavorable to creditors would have on the ability of developing states to attract outside capital. Haeger believes that the Bronsons and Butler are representative of a large group of New York state and eastern capitalists who played an important role in the development of the Old Northwest. He uses an impressive number of primary and secondary sources to document the contributions of these three men. He demonstrates the importance of examining the actions of individuals contributing to economic development and emphasizes the links between East and West existing in the 1830s and 1840s. He is less successful in generalizing from the activities of these three eastern capitalists to the overall impact of eastern capital and capitalists on western economic development. The evidence is suggestive, but the amounts actually moved by the three New Yorkers were quite small in comparison to the total flow of funds during the period. Some readers may also be bothered by the emphasis on the importance of the individual. There is no convincing evidence presented to indicate that western development would have followed a significantly different course without the involvement of these three individuals. Differences in interest rates between regions were an important reason for capital flows, but Haeger provides little evidence on interest rates and a discussion of regional rate differentials hardly enters the story. Considerable attention is paid to the development of the trust company, but there is little discussion of its long-run impact. Although Haeger has not convincingly demonstrated the effect of eastern capitalists on western development, he has provided a well documented and interesting story of several individuals and institutions who actively participated in organizational and institutional innovations in the early nineteenth century. The book can be read with profit by anyone interested in the financing of nineteenth century American development.


This study was conducted in the mountainous and forested areas of the Sylvo Pastoral Development Office in the North West of Tunisia (ODESYPANO), with 57 sma...


Kauṣītaki Upaniṣad (KṣU) contains narratives of encounters between wisdom teachers and those seeking knowledge. Ātman is frequently used in the sense of the "inner essence" of a thing or person in the KṣU, and described as annasyātmā, tejasa ātmā, śabdasyātmā, satyasyātmā, vāca ātmā, etc. The KṣU describes brahman as sitting on a throne and holding a conversation with a deceased person. Both Uddālaka Āruṇi and his son Śvetaketu are portrayed in a sympathetic manner in the KṣU. The grammatical forms of the KṣU that differ from classical Sanskrit have parallels in the oldest Upaniṣads.Keywords: Ātman; brahman; Kauṣītaki Upaniṣad (KṣU); Uddālaka Āruṇi


The Very High Temperature Gas-Cooled Reactor (VHTR) coupled to the High Temperature Steam Electrolysis (HTSE) process is one of two reference integrated systems being investigated by the U.S. Department of Energy and Idaho National Laboratory for the production of hydrogen. In this concept a VHTR outlet temperature of 900 °C provides thermal energy and high efficiency electricity for the electrolysis of steam in the HTSE process. In the second reference system the Sulfur Iodine (SI) process is coupled to the VHTR to produce hydrogen thermochemically. This report describes component sizing studies and control system strategies for achieving plant production and operability goals for these two reference systems. The optimal size and design condition for the intermediate heat exchanger, one of the most important components for integration of the VHTR and HTSE plants, was estimated using an analytic model. A partial load schedule and control system was designed for the integrated plant using a quasi-static simulation. Reactor stability for temperature perturbations in the hydrogen plant was investigated using both a simple analytic method and a dynamic simulation. Potential efficiency improvements over the VHTR/HTSE plant were investigated for an alternative design that directly couples a High Temperature Steam Rankin Cycle (HTRC) to the HTSE process. This work was done using the HYSYS code and results for the HTRC/HTSE system were compared to the VHTR/HTSE system. Integration of the VHTR with SI process plants was begun. Using the ASPEN plus code the efficiency was estimated. Finally, this report describes planning for the validation and verification of the HYPEP code.


This paper studies the effect of remittances sent home by South African labor migrants beyond higher levels of consumption on socioeconomic outcomes childrens schooling in particular. We use cross-sectional data from the 1993-1994 Integrated Household Survey and panel data from 2002 and 2003 Labor Force Survey. We find that migration and remittances practices are largely restricted to Blacks. In recipient households remittances substantially increase the likelihood that children are in school through three pathways associated with increased household income: increasing household educational spending reducing child labor and mitigating the negative effect of parental absence due to out-migration. Also migrant households without remittances are distinguished from remittances households. Children in these households are shown to be disadvantaged compared to recipient households and sometimes even worse-off than their counterparts in nonmigrant households primarily due to the deleterious effect of parental out-migration with no economic compensation. Sensitivity tests (fixed-effect modeling using panel data) show that the migration and remittances effect is robust to endogeneity and relatively consistent across subsamples and over time albeit the negative effect of being in migrant households with no remittances is largely reduced over time along with relaxing migration policies. The paper also includes analyses designed to assess the social consequences of the remittances effect. We find that remittances help reduce intra-familial gender inequalities as well as inter-familial racial and SES (income and rural/urban residence) inequalities in schooling among recipient households. (authors)


The hamster adrenal gland was found to be a new and very potent source of "sperm motility factor" (SMF); the activity of SMF in adrenal extracts was approximately 100 to 200 times that in hamster blood serum. Hamster epididymal spermatozoa incubated with adrenal extracts became capacitated. as shown by their ability to fertilize cumulus-free eggs. Like the SMF in human blood serum, the hamster adrenal SMF has a low molecular weight (about 100 to 200) and is heat-stable. in depends the


Two-phase flow pipelines are utilized in simultaneous transferring of liquid and gas from reservoir fields to production units and refineries. In order to obtain the hydraulic design of pipelines, pressure drop and liquid holdup were calculated following pipeline flow regime determination. Two semi-empirical and mechanistical models were used. Empirical models e.g. Beggs & Brill, 1973, are only applicable in certain situations were pipeline conditions are adaptable to the model; therefore we used the Taitel & Dukler, 1976, Baker et al., 1988, Petalas & Aziz, 1998, and Gomez et al., 1999, mechanistical models which are practical in more extensive conditions. The FLOPAT code was designed and utilized which is capable of the determining the physical properties of the fluid by either compositional or non-compositional (black oil) fluid models. It was challenged in various pipeline positions e. g. horizontal, vertical and inclined. Specification of the flow regime and also pressure drop and liquid holdup could precisely be calculated by mechanistical models. The flow regimes considered in the pipeline were: stratified, wavy & annular (Segregated Flow), plug & slug (Intermittent Flow) and bubble & mist (Distributive Flow). We also compared output results against the Stanford Multiphase Flow Database which were used by Petalas & Aziz, 1998, and the effect of the flow rate, pipeline diameter, inclination, temperature and pressure on the flow regime, liquid holdup and pressure drop were studied. The outputs (flow regime, pressure drop and liquid holdup) were comparable with the existing pipeline data. Moreover, by this comparison one may possibly suggest the more suitable model for usage in a certain pipeline.Copyright © 2006 by ASME


Thank you for reading molecular models of life philosophical papers on molecular biology. As you may know, people have look hundreds times for their favorite novels like this molecular models of life philosophical papers on molecular biology, but end up in malicious downloads. Rather than reading a good book with a cup of coffee in the afternoon, instead they cope with some infectious bugs inside their computer.


Abstract:This article analyzes the different configurations of subjectivity in Daniel Burman's El abrazo partido (2004) and Gaston Solnicki's Papirosen (2011). In both films, the self is presented through others. Their families and places of belonging allow the protagonist of the former film and the director/narrator of the latter to reflect on both past and present. By examining the others, they are trying to locate themselves in a larger historical narrative: the history of Jewish families that have survived the Holocaust and escaped World War II, ultimately migrating to Argentina. With dissimilar aesthetics, each film offers a distinct formation of the self, but both reveal a sense of disenchantment with reality and the broken family ties. In this context, a double ethical obligation emerges: one related to the confrontation with the others and another one related to belonging to a third generation of exiled Jewish families looking for their own role in the torn history.


The present invention relates to a class of amino acid and glucopyranosyl-arabinofuranosyl novel amino acid heavy metal chelating agent, to processes for their preparation and to their use and compositions containing them for the treatment and prevention of heavy metal poisoning.


Before the building of C4ISR,it's function requirements should be made clear.As is well known to us,index system is an important part of the function requirements.While the index system is not always set up correctly because of the builder's limited experience,the circumstance and the ability.In this paper the problem of the common methods during the construction of index system of C4ISR function requirements is analyzed.Then the WER-based method is put forth,which would do well with the four main aspects of the index system,such as the generality,the representativeness,the effectiveness and the reliability.


Loosening of the tibial component continues to be a major cause of failure in cemented total knee arthroplasty. Much of the cement applied to the device does not penetrate evenly into the trabecular bone due to cement leakage along the outer margins of the component during implantation which may ultimately translate into compromised fixation. Achieving uniform penetration to 3 4 mm has presented a challenge with current implants. A new stemless rimmed cemented tibial component (SRCTC) was designed featuring a 3 mm rim patterned in the perimeter shape of the Zimmer Natural Knee II (NKII) tibial baseplate and the elimination of the antirotational stem extending from the center. The purpose of the 3 mm rim was to provide a cement well that limits outer margin leakage, promotes uniform cement penetration, and is 80% shorter in profile than the NKII implant. The goal of this thesis was to compare the SRCTC s rotational stability, cement containment, and cement penetration characteristics against those of the NKII. Six pairs of cadaveric tibia with similar demographics were implanted with the SRCTC and NKII and subjected to torsonial testing. Specimens were sectioned and analyzed using backscattered electron microscopy and image analysis software. Tibias implanted with the SRCTC had on average significantly more trabecule in the cement mantle (p=0.02) and those trabecule were closer to the underside of the implant (p=0.06). No significant differences between the two implants were noted following torque testing (p=0.42). The means of cement penetration depth along the length of the implant , t t i l t. l t i t i t t ' t ti l t ilit . t t i t, t t ti t i ti i t t t II. i irs f ri ti i it si il r r i s r i l t it t II s j t t t rs i l t sti . i s r s ti l si s tt r l tr i r s i l sis s ft r . i i s i l t it t r si ifi tl r tr l i t t a tle ( . ) a t se tra ec le ere cl ser t t e ersi e f t e i la t ( . ). si ifica t iffere ces et ee t e t i la ts ere te f ll i t r e testi (p 0.42). he eans of ce ent penetration depth along the length of the i plant (p=0.18) and at the perimeter (p=0.13) differed, but were also not significant. The SRCTC s rim limited cement extrusion during implantation for all tibial pairs, potentially reducing the threat of third body wear following implantation. Comparable levels of rotational stability and cement penetration depths for an 80% shorter implant may be an asset to future minimally invasive surgical procedures. Future studies may incorporate axial loads to replicate tibial forces experienced in vivo. Lever-out mechanical testing may also provide further insight into the posterior and anterior stability of the SRCTC implant versus other implants containing stems like the NKII.


Rapid modernization and exponential sophistication have taken place over the last few years in the field of medical sciences. These undoubtedly have increased longevity and relief from sickness but a lot is desired to be done with regard to handling care and attention to those who are sick and even to those who are dead & need to be laid to rest and peace with dignity and respect.


Abstract: Pragmatic presupposition is a common linguistic phenomenon in natural language. In real life, an increasing number of people begin to use pragmatic presupposition to carry out interpersonal communication, so as to make the expression richer and more accurate. However, while the appropriate use of pragmatic presupposition is related to the effectiveness of communication, many people cannot attach great importance to the significance of pragmatic presupposition and fail to understand its role in interpersonal communication. This paper takes pragmatic presupposition theory as the theoretical basis and lovers' dialogues as an example to analyze the application of pragmatic presupposition in a specific context with the aim of helping people fully understand pragmatic presupposition theory and promote the effect of interpersonal communication in specific contexts.
Key Words: pragmatic presupposition, dialogue, boyfriend and girlfriend, interpersonal communication


A key pre-election spoken genre in several modern democracies is unarguably the manifesto launch speech. Yet, it has surprisingly received either very little or no scholarly attention. Consequently, from a rhetorical perspective, this study examined the schematic structure of three keynote speeches delivered by presidential aspirants of three leading political parties in Ghana – New Patriotic Party (NPP), National Democratic Congress (NDC), and the Convention People's Party (CPP) – to launch their political parties' manifestos in 2016. The three speeches delivered by the presidential candidates of the three parties constituted the data set for the study. Applying the popular Swalesean rhetorical move analysis, originally meant for the academic setting, the study identified the use of a nine-move pattern as the schematic structure for the genre across the three speeches, with four ambiguous moves. These findings of the study have implication for the standardizing of the schematic structure of manifesto launch speeches worldwide and, thus, contributes to the scholarship on the political manifesto genre, political communication as well as further research on manifesto launch speeches in other democracies around the world.


In the early 4G deployments, mobile communication providers have been focusing on connectivity technologies to meet the coverage and capacity needs of the users. With the advent of 5G, however, new value-added services including Augmented Reality/Virtual Reality (AR/VR), Mission Critical (MC) applications need to be supported. Open Radio Access Network (RAN) together with network slicing technology has been envisioned as one of the important solutions to realize Ultra Reliable Low Latency Communication (URLLC) services in 5G. The paper explores a novel framework and its under-pinning key enablers to deliver the ultra-low latency specifications for various 5G verticals including Smart Cities, Industrial Internet of Things (IIoT) and MC Services.


Triboelectric nanogenerators (TENGs), which are combined effects of triboelectricity and electric induction, is a large-area and low-cost technology that can be applied easily in our life. In this work, we applied life supplies to TENGs and analyzed a type of chemical bonding with the ratio of C-C/C-H/C-O/C=O bonding. As the ratio of C-C bonding increases, the materials can be positively charge. On the other hands, as the ratio of C-H bonding increases, the materials can be negatively charged materials. Based on these behaviors, we got a voltage of 210V, a current of 14.6 μA and a maximum power of 9.8mW. Finally, we could turn on 97 light emitting diodes (LEDs) by using a wrap as a negative material and a magnetic note as a positive material. 초 록: Triboelectric nanogenerators (TENGs)는 정전기 기반의 마찰 전기 발전기로써 간단한 구조로 저비용, 대면 적으로 손쉽게 활용할 수 있는 기술이다. 본 연구에선 생활 용품을 활용하여 화학적 결합 및 SEM image로써 분석 을 하고 C-C/C-H/C-O/C=O bonding에 따라 bonding 조성비에 따라 C-C bonding의 비율이 클수록 음전하, C-H bonding 비율이 클수록 양전하 대전체가 되는 것을 확인하였다. 그러한 특성을 가지고 최적 생활용품을 활용하여 정전 출 력 실험을 했을 때 최대 210 V, 14.6 μA, 9.83 mW의 출력을 얻었다. 최종적으로, 랩과 마그네틱 노트를 이용해 97개 의 Light Emitting Diodes (LEDs)를 점등할 수 있었다.


In the new period of economic development, geological work is the foundation of economic building and is needed in the whole process of economic development. Therefore how dos geological work gives better and more overall service for the state and society -- this is important problem worth to think by geological workers for practice of the important thought of three represents. The paper discusses the directions and contents of the unprofitable national geological organizations and analyzes the demands of the Shanbei energy and chemical industry basis development for geological work and thinks that we only combine the national geological work with provincial (regional) economic development planning and can make geological work efficiently serve social and economic development. Then the authors emphasizes the significance of expanding the service field of geological work and think that we must have the new concepts and use the new means to fit the new requirements in the new era when we implement national geological work. Only we more initiatively serve social and economic development and can carry out the important thought of three represents.


Carbon fibers (CFs) are made mostly from a non-environmentally friendly polyacrylonitrile (PAN) and little from rayon. PAN-based CFs, require huge amount of energy for its production aside its contributions to the global CO2 emission. Therefore, there is recourse to a more environmentally friendly sources of CFs biomass. Recently lignin has been recognized as a potential renewable raw material for carbon fibers to replace PAN-based. The magnitude and quality of CO2 emission of lignin-based CFs are dependent on the processing route. On this premise; this review examines the various lignin-based CFs processing route adopted by researcher in the recent past to establish the most viable route with minimum carbon footprint emission. Outcome of the review shows that the major advantages of aromatic polymer (AP) generated precursor over PAN is the presence of higher quantity of guaiacyl units and oxygen content which makes the stabilization phase efficient and faster requiring less energy. Though there are several methods and options for the various stages of conversion of lignocellulosic biomass into CFs as highlighted in the study, establishing an optimum processing route will be a trade-off amongst various issues of concern; carcinogenic risk, carbon footprint emission, CFs Yield and mechanical strength of the CFs. Inferences from the study shows that the L-CF significantly produced reduced climatic impact in terms of CO2 emission.


The SIEBM (Iberian Symposium of Studies on Marine Biology) has a long tradition. The conference was first convened in 1979 and it has since been held approximately biannually. It was originally focused on marine benthos, but two editions ago it was decided to widen its objectives to include other related subjects. The 15th edition was held at the University of Alicante from 6th to 10th September 2010.


Objective:To investigate the curative efficiency of integration of Chinese medicine Uremic Clearance Granules(UCG) and western medicine(WM) on chronic renal failure(CRF) in improvement for renal function and retard for progression of CRF. Methods:236 patients with CRF were randomly divided into control group(n=118) which was treated with WM alone and treated group(n=118) which was added with oral UCG 25 to 40 grams everyday for two months. The curative efficiency , which was assessed by the changes of serum creatinine(Scr),BUN,and clinical signs and symptoms, was compared between two groups together with side effect and progression of CRF. Results:The overall effective rate(60.17%) in treated group was significantly higher than that(22.88%) in control group(P0.01). All the clinical signs and symptoms in treated group had been ameliorated with the rates more than 70%, which were significantly higher than that in control group respectively(P0.05). Both Scr and BUN were significantly decreased (P0.01), and the level of red blood cells (RBC) was significantly increased (P0.05) after the follow-up of two months in treated group,but the changes of these indices in control group were not significant. Furthermore,in treated group,the curative efficiency of the patients with Scr≤442 μmol/L was significantly superior to that with Scr≥451 μmol/L(P0.01),but only 2 of 18 cases with Scr≥ 707 μmol/L showed effective,that there was no significance compared with control group (P0.05). During the follow-up of one year, 5 of 18 cases in treated group entered the end-stage renal disease (ESRD), while 13 of 20 patients in control group did. A significant difference existed (P0.05). Eventually, there was no obvious side effect during the follow-up. Conclusion:The curative efficiency of integration of Chinese medicine UCG and WM on CRF is better than that of WM alone. UCG can improve renal function and retard the progression of CRF.


In the process of prototyping,precision and surface quality is very important. Experiments have shown that oval distortion happens for cylindrical object and cylindrical holes during SLA manufacturing. It will analyze the phenomenon and make some suggestions for improvement.


The invention discloses an implementation method for carrier aggregation in a wireless communication system. The method includes: configuring a cell which is composed of a primary carrier and a plurality auxiliary carriers, and using the primary carrier to send system information and/or synchronize signals and/or pilot frequency publicly; configuring the use of the auxiliary carriers through a system. The invention further discloses an implementation system for carrier aggregation in the wireless communication system. A configuration unit is used for configuring the cell which is composed of the primary carrier and the plurality auxiliary carriers. By the method and the system, meaningless power consumption of a base station and interference to neighboring cell signals are avoided.


Introduction ICONIC is a prospective, multi-country (n=33) observational study, assessing cumulative burden in adult ulcerative colitis (UC) patients (pts) under routine care. Assessments of healthcare resource utilisation (HCRU), disease severity and impact on quality of life will be captured at 6 month intervals through 2 years. This analysis evaluated baseline (BL) HCRU, work productivity, and quality of life among UC pts with different level of disease severity. Methods Pts with early UC (diagnosed ≤36 months) were enrolled irrespective of disease severity or treatment. For this analysis, we evaluated pts stratified by physician assessment of disease severity into severe, moderate, mild and remission groups. BL characteristics described: Simple Clinical Colitis Activity Index (SCCAI), UC-related HCRU measured during the 6 months prior to study enrollment (i.e., visits to treating physicians or other IBD-associated healthcare professionals, emergency room (ER) visits, hospitalizations and hospital admissions for surgeries); Health Related Quality of Life (HRQoL), pt-reported employment/UC-related sick leave status and Work and Productivity Activity Index (WPAI:GH; including work time missed (absenteeism), impairment while working (presenteeism), overall work productivity impairment, and daily activity impairment domains). Results A total of 1816 UC pts were enrolled; mean ±SD age was 38.5±14.6 years and 833 (45.9%) were female. At BL, 230 pts (12.7%) were in remission, 672 pts (37.0%) had mild UC, 668 pts (36.8%) had moderate UC, and 234 (12.9%) had severe UC. Compared to pts in remission, pts with moderate to severe UC had 1.8 to 2.6-fold higher rates of hospitalizations and 1.6 to 2.5-fold higher rates of ER visits over the past 6 months. Pt with moderate and severe disease were associated with lower SIBDQ scores and higher WPAI:GH domain scores (i.e., greater impairment on work productivity) than pts with mild disease or those in remission. 172 (9.5%) pts reported to be unemployed at BL. 183 (10.1%) reported sick leave at BL. Sick leave time ranged from <2 months (59.6%), 2–4 months (12.6%),>4 months (22.4%). Conclusion The direct and indirect burden of UC is substantial, as measured by healthcare resource utilisation and work-life impact. Pts with moderate and severe UC not only were associated with higher rates of urgent care in hospitalisation and ER visits, but also with poorer quality of life, higher unemployment, sick leave and impaired work productivity than pts with mild UC or in remission. For pts with mild UC, despite comparable HCRU to pts in remission, increased impact on work productivity remains a concern.


Buffer composition affects the pattern of inactivation of B. cereus beta-lactamase I by dicloxacillin. At pH 7.0, in the presence of phosphate ions, dicloxacillin appears to cause essentially an irreversible inactivation of the catalytic site of the enzyme, while in a tris-cacodylate buffer the inactivation process appears to affect essentially the substrate-binding site. Buffer ions act presumably by interacting themselves with either the catalytic or the substrate-binding site of the enzyme, thus modifying the affinity of these sites for the halogenated isoxazolyl-penicillins.


The invention relates to an ultrasonic positioning blood vessel therapeutic device and control technology. The therapeutic device consists of a diagnostic ultrasonic transmitting and receiving part, a therapeutic ultrasonic transmitting part, a system control part, an ultrasonic sound head, a display and a power supply operating part, wherein the operating part turns on a power supply to connect the system control part; and the system control part consists of a storage circuit and a central control CPU, and sends instructions to turn on the diagnostic ultrasonic transmitting and receiving part, the therapeutic ultrasonic transmitting part, the ultrasonic sound head and the display. The control technology mainly makes use of ultrasonic Doppler Effect to detect blood vessel stenosis or obstruction, and transmits ultrasonic with therapeutic function after determining a lesion part of a blood vessel; moreover, the control technology can detect therapeutic effect in time and displays the detection result on a display screen.


We provide an alternative construction of a (2d+2)-vertex triangulation of S2×Sd−3. We generalize this construction to give a triangulation of Si×Sd−i−1.


A fluid product dispenser, a reservoir for storing a fluid product and gas (4), openings (15), a bottom portion (13), reducing the volume of the reservoir by being moved It said reservoir having a drive wall (11), the which can, each time the drive wall is driven, the administration opening serving as a passage of the fluid product to be sprayed (22), there to the reservoir (1) in Te, a little reaches the bottom portion (13), the plunger tube (4) extending in the form having a free end portion (41) that, on the opposite side of the free end portion, the porous body parts (13) and the plunger tube that has a connection end portion serving as a path for fluid products provided (42) (4), and, arranged between the plunger tube (4) dispensing orifice (22), capillary action to absorb fluid product by It has a porous body parts (3), and the point to be characterized, by having porous body parts (3) of the discharge end portion that is disposed in close proximity to the dispensing orifice (22) (31) dispenser that is, in.


Досліджено спосіб оцінки надійності комп'ютерних мереж на основі бінарної діаграми рішень (БДР). Розглянуто різні алгоритми обчислення надійності комп'ютерної мережі на основі БДР: алгоритм факторизації, алгоритм, що ґрунтується на пошуку мінімальних шляхів або перерізів, алгоритм створення БДР без отримання булевого виразу. Методи обчислення надійності на основі БДР дають змогу обчислити надійність мережі із сотень елементів. The present paper is aimed at investigating modelling and analysis techniques for the calculating the reliability of computer communication network using binary decision diagram. The network can be represented in a form of a graph, whose elements (vertices and edges) are considered as binary objects characterized by a working or a failed condition. Nodes and communication links of computer network may fail with known probability. The network
reliability is defined as the probability that all nodes, or a subset of the nodes, of the graph communicate through at least one path of working edges. Failure of a single component may directly affect the functioning of a network. Determination of the probability properties of the network is based on Binary Decision Diagram and Shannon's decomposition principle. Binary decision diagram is a modern data structure proved to be compact in representation and efficient in manipulation of Boolean formulas. A path is defined as asset of edges so that if these edges are all up, the system is up. A path is minimal if it has no proper subpaths. A cut is defined as a set of edges so that if these edges are all down, the system is down. A cut is minimal if it has no proper subcuts. Different approaches are based on the use of BDD. One is factoring algorithm. The idea is to choose an edge and break the model down into two cases:
the first assumes the edge has failed, the second assumes it has not failed. For each case, a new
reliability graph is built by taking into account the behavior of the chosen edge. The alternative class of methods is to directly obtain minpaths or mincuts. Minpaths are searched by means of the Dijkstra algorithm, while mincuts are searched by means of a recursive algorithm. In these methods we first enumerate all the minpaths and mincuts of the given network and then the reliability expression is evaluated using different methods, like inclusionexclusion method or sums of disjoint products. There are some disadvantages in the above methods. In the factoring algorithm, the number of factored reliability graphs will increase exponentially with the number of edges increases. In the minpaths or mincuts methods, as the number of edges becomes large, the number of minpaths or mincuts will be large and inclusion-exclusion or sums of disjoint products expression will be increased too large. Size of BDD strongly depends on the ordering of variables. The size of BDD means the total number of non-terminal vertices in the BDD and the number of vertices in particular level. There is no polynomial search algorithms for optimal variable ordering. The present paper introduces BDD representation of the 2-terminal connectivity of a graph without preliminary search for the minpaths or mincuts. The algorithm starts from the source node and visits the graph until the destination node is reached. The BDD construction starts recursively once the destination node is reached. The BDD's of the nodes along a path from source node to destination node are combined in AND. If a node possesses more than one outgoing edge the BDD of the paths starting from each edge are combined in OR. A bridge network with directed arcs is considered as an example under assumption that only arcs can failure.


The authors investigated business faculty members' degree of Power-Point (PPT) use across different functional areas in a business program and their use of specific PPT features. The authors also examined students' perceptions of PPT's effectiveness across different business courses (e.g., accounting, economics, management, business law, marketing). After discussing the findings, the authors offer practical tips for effectively using PPT.


The author summarizes the theoretical results in "A discrete optimal control problem for descriptor systems," [IEEE Trans. Automat. Control, vol.34, pp.177-181, 1989] and "Authors' reply to 'Comments on 'A discrete optimal control problem for descriptor systems"," [ibid., to appear], and uses them in the computer-aided optimization problem for descriptor systems. An efficient algorithm for computing the optimal solution sequence of the optimization problem is developed and an example of the macroeconomic systems is shown.


In a percentage of both pre-and postmen opausal women, the endometrium can become hyperplastic when subjected to prolonged stim ulation by either endogenous or exogenous es trogens in the absence of progesterone or a progestogen. 1,2 The reasons why some but not all women exhibit this abnormal response are un clear, but possible mechanisms include disor dered estrogen production; reduced plasma binding of the circulating estrogen, whereby more of the steroid becomes free to transfer into responsive cells; 3 and increased sensitivity of the endometrium to the estrogenic stimulation. 4 Hyperplasia is an abnormal increase in the amount of proliferative endometrium which ex hibits varying degrees of architectural and cy tologic atypia, and two distinct forms are recog nized. In cystic hyperplasia, the endometrium is diffusely affected, although polypoid projections may form. The epithelial glands vary widely in diameter and are lined by a high cuboidal or columnar epithelium which may become multilayered. The stroma appears hypercellular because the constituent cells are plump and closely packed. Adenomatous hyperplasia is a term reserved for a spectrum of changes that may be either focal or diffuse. The glands are crowded in the affected areas, while the epithelium may show pseudostratification and the glands infolding and budding. As the hyperplasia becomes


Cloud computing is a model for enabling ubiquitous, convenient, on-demand access to a shared pool of configurable computing resources. Cloud computing and storage solutions provide users and enterprises with various capabilities to store and process their data in third-party data centers. It relies on sharing of resources to achieve consistency and economies of scale over a network. Biometrics refers to metrics related to human characteristics. Biometrics authentication is used in computer science as a form of identification and access control. It is also used to identify individuals in groups that are under surveillance.


Tri-layer graphene can have two stacking orders, ABA (Bernal), and ABC (Rhombohedral) staking, which have different energy band structures near the K point. Optical and electrical properties of the boundary between ABA and ABC stacking are interesting in studying the fundamental science of graphene. The Raman spectra of ABA- and ABC- stacked tri-layer graphene have been reported[1,2], but photocurrent in those tri-layer has not been studied. We measured photocurrent in ABA- and ABCstacked tri-layer graphene photodevices as a function of the back-gate bias and the incident polarization. The tri-layer graphene photodevices were fabricated by depositing Pd/Au electrodes on exfoliated trilayer graphene on SiO2-covered silicon substrates by using e-beam lithography. The ABA and ABC stackings in tri-layer graphene were confirmed by the 2D band of the Raman spectrum. Photocurrent images were taken by scanning a focused laser beam across the photodevice. Raman spectra and photocurrent images were taken simultaneously in order to identify the exact position of the photocurrent, so that we can match the photocurrent and the stacking order where the photocurrent is measured.


What right does a psychiatrist or other mental health prof essional have to refuse to treat an institutionalized mental patient? Obviously, if the patient wants to be treated or, as is more commonly the case, does not object to treatment, the psychiatrist must treat, since that is what he is being paid to do. Let us assume, however, that the patient objects to being treated, but, under the law of the state in which he is institutionalized, has no right to refuse treatment. The issue then is whether the psychiatrist, under those circumstances, has the right to refuse to treat.


(57) Abstract: operating systems and unauthorized access to the corresponding subroutine is adapted to be blocked through the keyboard associated with the floppy drive mechanism. The A subroutine is a file in ROM (BIOS), when access to the floppy drive mechanism, is detected whether or not the information stored on the floppy are present, if the information does not exist, Through the subroutine of the computer keyboard and ROM (BIOS), merely available subroutine menu execution type user Surface, if the information is present on a floppy, a computer keyboard and RO Through the subroutine (BIOS) that is a file to M, it is stored on the hard disk, to be accessible to the subroutine of the operating system and the menu-executing user Surface.


BACKGROUND
 Needle stick injuries (NSIs) are major risk for blood-borne pathogen exposure in hospital. A benchmark for the prevalence of NSIs would allow hospital to compare data with those of other institutions and also assist with the development of measures to minimize NSIs. .

 OBJECTIVE
 To determine the incidence of accidental NSIs from 2013 to 2017 at same time to promote awareness among the healthcare workers (HCW) in Selayang Hospital, Malaysia.

 METHODS
 This was a retrospective cohort using secondary data obtained from the medical records. Descriptive and inferential statistics were computed to analyse the data.

 RESULTS
 A total of 220 NSIs cases and out of witch majority were female (n=165, 75%) compared to male (n=55, 25%) with ratio of 3:1 respectively. The average age was 30.6± 7.0 SD. Most common causes NSIs which was hypodermic needle (n=126, 57.27%) follow by stylet needle (n=40, 18.18%) however suture needle (ORs=5.4, p-Value=0.03) shows significant association with time of injury. There were 44 cases of NSIs per year. All HCW are follow-up with some HCW received post exposure prophylaxis.

 CONCLUSIONS
 Various measures must be implemented in hospital setting to minimize the risk of sustaining NSIs. The health promotion play key role to deliver information to HCW.


The measurement of air flows in internal combustion engines, such as occur in gas-exchanging or in the combustion chamber, is very difficult because of their great unsteadiness and complexity. The present paper treats of the availability and limitations of repetitive spark method in visualization and quantitative determination of such kinds of flows. The following are the results derived from the investigation. Although this method is absolutely accurate for a steady parallel flow, the acceleration produces considerable errors owing to the bouyancy of the hot zone heated by the discharges. The induced relative velocity caused by this effect is proved to be proportional to the equare root of the acceleration. Further, some applications of this spark method to evaluate the flow in the internal combustion engines are presented, of which one shows the flow patterns in the suction port and around the valve, and the other the swirls produced in the cylinder and in the swirl chamber.


Abstract : This paper describes a highly effective two-semester client-oriented team-based approach in which students get their first "real" research and development experience in a carefully guided environment that fashions theory into product. Examples used describe how a problem space in mobile devices can be scoped to design tenable software solutions and then how to build one of these designs into what a customer seeks, thereby effectively providing what society increasingly requires from educational institutions in developing mobile device applications.


This text has introduce PKI technology, has analyzed the assurance information privacy, integrality how the figure signs and resisted the denying, and how both parties carry on identity authentication, provide the application of the technology of the digital signature in the safe and secret system of e-commerce.


Cashew is an economically important tropical crop. On average, 52 percent of the raw cashew nut processed in India was imported.

In recent years, the decreased supply of raw cashew nuts and increased demand for processing forced the cashew sector to

concentrate on increased domestic production. To understand the area, production and productivity scenario of cashew nut; India

was divided into eastern and western regions based on the traditional area of cashew cultivation along the coasts. The growth in the

area under cashew and production of cashew nuts were examined from 2000-01 to 2017-18. Compound Annual Growth rate of area

for eastern and western regions was 2.98 and 1.06 percent respectively. The growth rate of production was calculated as 2.08, and

3.55 percent and productivity growth were calculated to be 2.98 and 1.06 percent for eastern and western regions, respectively. The

overall average productivity of different varieties in the western and eastern regions was 16.08 and 10.83 kilograms per tree.


We propose an approach for the simultaneous reconstruction of the electromagnetic and acoustic material parameters, in the given medium $\Omega$ where to image, using the photo-acoustic pressure, measured on a single point of the boundary of $\Omega$, generated by plasmonic nanoparticles. We prove that the generated pressure, that we denote by $p^{\star}\left(x, s, \omega \right)$, depending on only one fixed point $x \in \partial \Omega$, the time variable $s$, in a large enough interval, and the incidence frequency $\omega$, in a large enough band, is enough to reconstruct both the sound speed, the mass density and the permittivity inside $\Omega$. Indeed, from the behavior of the measured pressure in terms of time, we can estimate the travel time of the pressure, for arriving points inside $\Omega$, then using the eikonal equation we reconstruct the acoustic speed of propagation. In addition, we reconstruct the internal values of the acoustic Green's function. From the singularity analysis of this Green's function, we extract the integrals along the geodesics, for internal arriving points, of the logarithmic-gradient of the mass density. Solving this (internal) integral geometric problem provides us with the values of the mass density function inside $\Omega$. Finally, from the behavior of $p^{\star}\left(x, s, \omega \right)$ with respect to the frequency $\omega$, we detect the generated plasmonic resonances from which we reconstruct the permittivity inside $\Omega$.


The dynamics of a chain of two and three spins coupled at both ends to separate bosonic baths at different temperatures is studied. An exact analytical solution of the quantum master equation in the Born-Markov approximation for the reduced density matrix of the chain is constructed. It is shown that for long times the reduced density matrix converges to the nonequilibrium steady-state. Dynamical and steady state properties of the concurrence between the first and the last spin are studied.


Implementation of Competency-Based Curriculum in 2004, known as KBK, which was followed by the Education Unit Level Curriculum in 2006, known as KTSP, has demanded an increase of teacher quality. This of course implies that eventually every school educational institutions in great need of qualified teachers and adequate in carrying out their duties at school. Therefore the implementation of the curriculum can be run as expected by many, then there needs to be upgraded on the ability of teachers. This article will try to discuss the improving teacher competency in Classical Learning Management according to the purposes of the two curriculums. Kata Kunci: Kompetensi, pengelolaan pembelajaran, kurikulum berbasis kompetensi, pengelolaan kelas


Endothelin‐1(ET‐1) is a potent vasoconstrictor involved in the development of cardiovascular diseases and is an important regulator of heart development. However, the role of ET‐1 in cardiac differentiation of mouse embryonic stem cells (mESCs) and the underlying molecular mechanisms remain poorly understood. In the present study, we showed that ET‐1 significantly up‐regulated gene expression of the cardiac specific transcriptional factors Nkx2.5, GATA4, and conduction system specific marker CX40, with no affect on the gene expression of α‐MHC and β‐MHC in cardiac differentiation of mESCs. The percentage of beating embryoid bodies (EB) and the Troponin T (TnT) positive area in total EBs was unchanged following ET‐1 treatment, while the percentage of spindle cells that stained positively with TnT was increased in the presence of ET‐1. Further investigation indicated that the percentage of beating EBs and the TnT positive area were decreased by the extracellular signal‐related kinases (ERK)‐1/2 inhibitor U0126 and the p38 inhibitor SB203580, but not by the Jun amino‐terminal kinases (JNK) inhibitor SP600125. Inhibition of ERK1/2, p38, and JNK pathways also blocked the up‐regulation of Nkx2.5 and GATA4 by ET‐1, however only inhibition of the ERK1/2 pathway had negatively effects on the increase in CX40 expression in response to ET‐1. ET‐1 induced an increase in the percentage of spindle cells was also inhibited by U0126. Our results suggest that ET‐1 plays a significant role in the cardiac differentiation of mESCs, especially in those cells committed to the conduction system, with the ERK1/2 pathway playing a critical role in this process. J. Cell. Biochem. 111: 1619–1628, 2010. © 2010 Wiley‐Liss, Inc.


The present invention, hydrocarbons comprising the steps of - relates to a method of containing a source: a) from a fixed-bed hydrotreating step, b) hydrotreating step a) of the effluent any separation step of originating from, c) steps a) origin outflow least part or phase of the water b) cracking at least a portion of of the hydrochloride heavy fraction phase originating from, d) step c) maturation of the heavy liquid fraction originating from the effluent separation step, e) the separating step d) originating from step, f) maturation step e) separation stage of the precipitate from the heavy liquid fraction originating from.


: Multipotent interstitial stem cells in the freshwater polyp Hydra define one of the best-studied pre-bilaterian adult cell lineages. Most of them represent a population of small, fast-cycling cells that give rise to three somatic differentiation products (neurons, nematocytes, and gland cells) under conditions of continuous asexual growth and reproduction, and they also form the gametes when sexual reproduction is initiated. Few proliferate with a longer cell cycle. Interstitial stem cells in Hydra and other marine hydrozoans have been studied intensively using sophisticated cellular and molecular methods over several decades. Here, we discuss the properties of interstitial stem cells in Hydra and the known feedback control mechanisms maintaining tissue homeostasis and spatial distribution of interstitial cells along the polyp's major body axis. We summarize the current state of knowledge about molecular regulation of self-renewal and somatic differentiation and put particular emphasis on those molecular factors that have been shown to affect decision making using methods of functional interference.


In a letter published in the October 2015 issue of Canadian Family Physician , Milburn wrote the following:

> [M]any authors talk of income equality as if there were a direct pathophysiologic pathway that leads from one's bank account to one's coronary arteries. How does one's heart sense


Introduction: Prospective Acquisition CorrEction (PACE) technique which directly measures the position of the diaphragm has been shown to be robust and provides high quality free-breathing abdominal MR images [1]. Particularly for T2-weighted 3DFT liver imaging, it is almost impossible to acquire the whole k-space data during a single breath-hold. Thus, using the PACE technique enables acquiring high-resolution full coverage 3DFT imaging. 3DFT data acquisition has the benefit of higher Signal-to-Noise Ratio (SNR) and enables the acquisition of thinner slices compared to multi-slice 2DFT imaging. Due to its long acquisition time however, T2-weighted Turbo spin echo (TSE) 3DFT imaging sequence has a relatively long echo train length (ETL). This long ETL makes it susceptibility to motion during data acquisition. For example, if there is irregularity in the patient breathing pattern, artifacts can exist in the image even with accurate navigator (NAV) triggering because the irregular breathings can vary the diaphragm position when acquiring near k-space center at the desired echo-time (TE). To overcome this, image-metric based motion correction algorithms can be applied to correct superiorinferior (SI) direction translational motion, but its processing time can be unacceptably long due to the size of the 3DFT data set [2]. In this work, we propose an alternative and simple method to decrease motion artifacts for 3DFT T2w-TSE imaging with PACE that are due to irregular breathing patterns. The method observes the navigator information before and after imaging and interpolates the motion patterns during the echo train acquisition.


Bovine mastitis is a common bacterial infection that causes inflammation of the mammary gland in dairy cattle. Staphylococcus is one of the most predominant and significant pathogens known to cause mastitis. Thus, this study was designed to isolate and assess the prevalence of Staphylococcus strains in dairy cattle with clinical mastitis in Region IV-A, Philippines. Baird Parker agar (BPA) supplemented with 5% egg yolk tellurite emulsion was used as selective media to differentiate coagulase-positive S. aureus and coagulase-negative staphylococcus (CNS). The isolated pathogens were phenotypically and genetically characterized for further identification. Surprisingly, out of 85 isolates, only 56.5% belong to the genus Staphylococcus and 43.5% were non-staphylococcus strains despite the use of a staphylococcus-specific selective medium. The overall most prevalent species among the isolates were S. chromogenes with an isolation rate of 21.2%. The antimicrobial resistance profiles of the isolated bacterial pathogens were also done. Several staphylococcal isolates exhibited resistance to multiple antibiotics. S. aureus showed hyper-resistance to three out of seven antibiotics – specifically streptomycin, clindamycin, and lincomycin. Surprisingly, most of the non-staphylococcal isolates exhibited hyper-resistance to multiple antibiotics. Proteus mirabilis, P. penneri, and Providencia stuartii showed almost 100% resistance and hyper-resistance to all antimicrobials tested except amoxicillin. These findings suggest that the detection of diverse species of mastitis-causing microorganisms is an important concern for the dairy sector, as different pathogens might represent different hazards and require distinct treatments, particularly on the type of antibiotics used to treat the infection. The erroneous choice of antimicrobial could unnecessarily expose the udder microbial flora to antimicrobials, thereby inadvertently promoting the emergence of multidrug-resistant pathogens that poses a serious threat to both animal and human health. Extreme antibiotic resistance detected in strains present in mastitic dairy cattle also raises a substantial public health concern, particularly when it comes to the consumption of food and food products, such as milk.


Laboratory sorption experiments were conducted to determine the extent to which soil organic matter derived from guayule (Partbenium argehtatum A. Gray) residues can affect the sorption of pendimethalin [N-(1-ethylpropyl)-3,4-dimethyl-2,6-dinitrobenzenamine]. Soils where guayule had been grown for 0 to 38 mo were collected for sorption experiments from beneath actively growing plants. An additional treatment was collected before planting cotton (Gossypium hirsutum L.) in a field 1 yr after the final harvest of guayule that had been grown for 36 mo was also included. Continuous guayule cultivation resulted in a modest increase in soil organic C from 0.29% (±0.01%) to 0.76% (±0.03%) after 38 mo of production. Pendimethalin sorption to the soil increased with increasing guayule organic deposition as measured by time under cultivation. Soils where guayule was grown for 38 mo had an organic C distribution coefficient, K OC , 23 times greater than the control soil where guayule had not been grown (389,400 vs. 16,900 L kg ―1 ). In the treatment before planting cotton, however, the combination of time and cultivation resulted in a reduction of K OC from 389,400 to 21,500 L kg ―1 . The use of pendimethalin in a guayule-cotton rotation requires sufficient time and primary tillage before planting cotton. In addition, the use of pendimethalin during regrowth of guayule from the stump following harvest may require higher application rates to control weeds. Adsorption of pendimethalin to soil using batch equilibrium indicated that soil beneath actively growing guayule has a higher sorption capacity for pendimethalin than soil without guayule.


'The men who now dictate Provo tactics are not members of the army council. They are thefollowers ofa man who goes under thepseudonym of"Murphy", who leads the South Armagh battalion. The activities of " Murphy's boys" have been remarkably vicious. They have no time for new-fangled political ideas in pursuing their aim to "get the Brits out". . ..It was undoubtedly the actions of the South Armagh Provisionals which finally convinced Mr Rees that he should regard the Provos not as terrorists, but as dangerous criminals, and that by ending detention he could allow the security forces to treat them as such. . . . The present chiefofstaff, Seamus Twomey, a former Belfast commander, is a perfect illustration ofthe Provos' flirtation with crime. He escaped from a Dublin jail in a hijacked helicopter in 1973, when he was serving not onlJ one yearfor IRA membership but also three yeats for possession of£1>574 stolen from a mail van'. (Sunday Times, 7 December 1975)


Sensitive High Resolution Ion Microprobe (SHRIMP) U-Pb zircon dating of pyroxene diorite from the Chaoshan gold deposit in Tonglin mineral district of Anhui Province indicates intrusive activity at 142.9±1.1 Ma. New U-Pb ages were obtained for quartz diorite from Tongguanshan quartz diorite and the Xinqiao Cu-S-Fe-Au deposit. These data indicate that mantle source magma-tic underplating occurred in Early Cretaceous (133~143 Ma). This suggests that magma-tism and associated ore-forming process became active in this area since the Yanshanian movement.


Virginia Lafond

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Figure.

Toronto, Buffalo, London: University of Toronto Press; 2002. 123 pp. $17.95 (paper) ISBN 0-8020-8532-6

Rating: **1/2

Audience: Patients with mental illness and their caregivers

Content : The central tenets of this self-help manual are that people


The research aims to determine the influence of company size, leverage, profitability, sales growth, audit committee, and cash flow operations against tax avoidance. Dependent variables in this study are tax avoidance while the independent variables used in this research are company size, leverage, profitability and audit committees. This research is focused on the LQ45 company listed on the Indonesia Stock Exchange (IDX) period 2015-2018. The selection of samples in this study used the purposive sampling method, thus obtained a sample of 51 sample data from the LQ45 company population listed on the Indonesia Stock Exchange (IDX) period 2015-2018. The analytical tools used in this study are multiple linear regression analyses. The results of this research show that the variable cash flow operations affect the tax avoidance, while the company size variables, leverage, profitability, sales growth and audit committees do not affect the tax avoidance.


Purpose: To assess the relationship between epilepsy and toxocariasis in adult subjects by means of a case–control study in Catania, Italy.


OBJECTIVE
2, 3, 5, 4'-Tetrahydroxy stilbene-2-O-β-D-glucoside (THSG), the active ingredient of Polygonum multiflorum, its polyketone reaction in the biosynthesis pathways was studied by biocatalysis method.

METHODS
The substrates 4-coumaroyl-CoA and malonyl-CoA were catalyzed in vitro by the crude enzyme extracted from Polygonum multiflorum callus, then the products were verified by HPLC and LC-MS methods. And the crude enzyme was analyzed by ammonium sulfate precipitation method and SDS-PAGE.

RESULTS
HPLC chromatogram showed the same retention time of both the product and resveratrol standards; LC-MS spectra showed that the m/z of product was 227, which was consistent with resveratrol standards under the mode of negative ion; Ammonium sulfate (AS) precipitation method showed AS of 40% - 70% had catalytic activity,and 50% - 60% was the optimum; SDS-PAGE showed protein bands were obviously different among different AS concentration between 20% - 80%, the protein band of 42 kDa was found in AS of 50% - 60%, which had the same molecular weight with stilbene synthase.

CONCLUSION
The product of polyketone reaction in the biosynthesis of THSG is resveratrol rather than THSG, so it is speculated that THSG is the conversion product of resveratrol instead of the direct product of the polyketone reaction.


This invention discloses a hot cracking-resistant phenolic resin for casting. The hot cracking resistant time of coated sand prepared from the phenolic resin is increased by 30-100%, and the other properties are also qualified for coated sand of steel casting. Besides, the hot cracking-resistant phenolic resin has a low cost, and is suitable for industrial production.


As shown by morphofunctional examinations of hypophyseal-adrenal system in 137 BA patients and post mortem examinations of adrenal cortex in 72 BA cases, most pronounced defects in glucocorticosteroid (GCS) biosynthesis and metabolism were recorded in patients on long-term GCS regiments (5-10 years and more). They displayed low levels of 11-OCS and 17-OCS, enhanced transcortin binding capacity, diminished adrenocortical reserves. Beclometasone propionate, endobronchial liposomes with hydrocortisone had no negative adrenal effects.


Introduction: Penetrating cardiac trauma (PCT) constitute a permanent surgical challenge due to it characteristics and high mortality. Aim: To describe the findings, outcomes and prognostic factors in PCT. Materials and Method: Cross-sectional descriptive study, review of prospective thoracic trauma protocols and surgical registries. Period January 1990-December 2017. All patients with PCT were included. Various variables are described and analyzed. Univariate and multivariate analysis were performed to identify factors associated with morbidity, neurologic dysfunction and mortality. Results: 220 patients PCT, 209 (95.0%) men, mean age 30.4 ± 13.3, median 27 years. Mechanism: Aggression in 202 (91.8%). The traumatic agent was cold steel in 186 (84.4%) and fire arm in 21 (9.5%). 169 (76.8%) patients presented with tamponade, 103 (46.8%) shock and 20 (9.1%) cardiopulmonary arrest. Approach was sternotomy in 157 (71.4%), left thoracotomy in 58 (26.4%). The most common injured areas were right ventricle in 110 (50.0%), left ventricle in 72 (32.7%). 135 (61.4%) patients needed postoperative ICU and 74 (33.6%) were transfused. Complications occurred in 60 (27.3%). Twenty-one (9.5%) were reoperated. Mortality 28 (12.7%). The postoperative median stay was 6 days (Range 1-150). Prognostic factors were identified. Discussion: Operated PCT are more frequent in men with stab wound, the most common injured area is the right ventricle. The morbidity and mortality is comparable with international series.