Quality of academic services is important for higher education institutions. This service reflects the quality of that institution. The assessment of whether the institution achieves good quality is determined by its users' perception. Therefore, achieving academic service satisfaction constitutes long term strategy requiring financial and human resources. This paper proposes some strategies for higher education institutions to achieve users' satisfaction. These include superior customer service; unconditional service guarantees or extraordinary guarantees; complaint handle; institutional achievement enhancement; and quality function deployment (QFD).


between healthcare and engineering could lead to significant improvements in the healthcare delivery system, essentially by recognizing that it is, in fact, a system of interlocked systems, each with its own work flows, resources, overhead, and product. Some of these systems deliver care directly, such as emergency room queuing. Others are more behind the scenes, such as cycling of IV pumps or maintaining operating room (OR) sterile packs.


This paper introduces the application of ceramic materials in the nuclear industry,including the nuclear fuel,absorber and moderator as well as the structure material of first wall and tritium-breeding materials used in fusion reactors and discusses the basic characteristics,relevant capacities,irradiation effect and main manufacture process of each ceramic component so as to meet the increasing requirement due to the development of nuclear industry.


The possibility to detect circumbinary planets and to study stellar magnetic fields through eclipsing time variations (ETVs) in binary stars has sparked an increase of interest in this area of research. We revisit the connection between stellar magnetic fields and the gravitational quadrupole moment $Q_{xx}$ and compare different dynamo-generated ETV models with our simulations. We present magnetohydrodynamical simulations of solar mass stars with rotation periods of 8.3, 1.2, and 0.8 days and perform a detailed analysis of the magnetic and quadrupole moment using spherical harmonic decomposition. The extrema of $Q_{xx}$ are associated with changes in the magnetic field structure. This is evident in the simulation with a rotation period of 1.2 days. Its magnetic field has a more complex behavior than in the other models, as the large-scale nonaxisymmetric field dominates throughout the simulation and the axisymmetric component is predominantly hemispheric. This triggers variations in the density field that follow the magnetic field asymmetry with respect to the equator, affecting the $zz$ component of the inertia tensor, and thus modulating $Q_{xx}$. The magnetic field of the two other runs are less variable in time and more symmetric with respect to the equator, such that the variations in the density are weaker, and therefore only small variations in $Q_{xx}$ are seen. If interpreted via the classical Applegate mechanism (tidal locking), the quadrupole moment variations obtained in the current simulations are about two orders of magnitude below those deduced from observations of post-common-envelope binaries. However, if no tidal locking is assumed, our results are compatible with the observed ETVs.


This picture is a portrait of Mary Ayres. This print was made from the original glass plate negative, which is housed at Virginia Historical Society.


Fungi of the genus Pneumocystis are widespread group of pulmonary pathogens infecting immunologically immature or unmunowmpromised humans and animals. Previous studies have ;horn significant interspecific differences in the Occurrence of P. carinii in mammals collected from the wild (41. The existing data indicates that infection with P. carinii is host-species specific but the reservoir of the infection has not yet been determined [7-81. The transmission of the fungus is known to be airborne. and the fungus has a dmant form that remains infective outside the mammalian host for at least several months [l]. The Occurrence of P. carinii docs not seem to be related to any particular habitat [4,6] but trcmendous gaps exist in understanding the epidemiology and ecology of Pnewnocysh organisms. In the present study, a histochemical technique was used to study the spatial distribution and Occurrence of P. carinii in the desert shrew, Notiosorex cran$ordi, in a fragmented landscape of southern California. A previous study [6] showed that the percentage of P . carinii infected individuals was higher in N. crawfordi than those in other synpatric small mammals.


Image classification is a complicated process of classifying an image based on its visual representation. This paper portrays the need for adapting and applying a suitable image enhancement and denoising technique in order to arrive at a successful classification of data captured remotely. Biometric properties that are widely explored today are very important for authentication purposes. Noise may be the result of incorrect vein detection in the accepted image, thus explaining the need for a better development technique. This work provides subjective and objective analysis of the performance of various image enhancement filters in the spatial domain. After performing these pre-processing steps, the vein map and the corresponding vein graph can be easily obtained with minimal extraction steps, in which the appropriate Graph Matching method can be used to evaluate hand vein graphs thus performing the person authentication. The analysis result shows that the image enhancement filter performs better as an image enhancement filter compared to all other filters. Image quality measures (IQMs) are also tabulated for the evaluation of image quality.


This research-action has, as main aim, to find a didactic solution with the problem of difficulties and gaps of learners of fourth average school year in what concerns their productions in French foreign language. Another inherent objective in this study is to fill the lack of empirical data in the field of group work and to analyse the peers verbal retroaction with the Algerian script inexperienced writers (Scardamalia & Bereiter, 1998). The investigation approach of this research-action will contribute to the controlled development of educational tools that enable the learning improvement of argumentative text production by reducing the mental load and the rate of information processing by learners using in approach, centered essentially on group work and the operation of revision. Resume: Cette recherche-action a comme objectif principal de trouver une solution didactique a l'epineux probleme des difficultes et lacunes chez des apprenants de quatrieme annee moyenne en ce qui a trait a leurs productions en francais. Un autre objectif inherent a cette etude est de combler le manque de donnees empiriques dans le domaine du travail de groupe et d'analyser l'influence de la retroaction verbale des pairs sur les competences scripturales de scripteurs algeriens novices (Scardamalia & Bereiter, 1998). La demarche d'investigation de cette recherche-action contribuera au developpement controle d'outils pedagogiques permettant d'ameliorer l'apprentissage de la production du texte argumentatif en allegeant la charge mentale et le taux de traitement des informations a l'aide d'une demarche centree essentiellement sur le travail de groupe et l'operation de revision.


Dr. F. C. Chao and al. have reported that smoking has only limited chronic effects on various platelet functions (1). Earlier investigations cited in their paper (2-4) as also others (5-7) showed a marked acute promoting effect of smoking on in vitro platelet aggregability. Our recent results presented below indicate that smoking has no acute effect on in vivo release reaction and in vitro platelet aggregability. 10 healthy men were investigated. In vivo release reaction of the platelets beta thromboglobulin (BTG, radioimmunassay in platelet poor plasma, Amersham) and platelet aggregability (Born's method, Chrono-Log aggregometer) were measured before and 10 min after smoking of two cigarettes within 20 rnin. We chose this limited time period, because all the positive results mentioned above have been found under similar conditions. In spite of some systemic effects of smoking (palpitation, tachycardia, headache, sweating, dizziness), BTG levels and aggregation curves remained unchanged for each person.


Brain metastasis is a common cause of mortality in cancer patients. Approximately 20-30% of breast cancer patients acquire brain metastasis, yet potential therapeutic targets remain largely unknown. The type I insulin-like growth factor receptor (IGFIR) is known to play a role in the progression of breast cancer and is currently being investigated in the clinical setting for various types of cancer. The present study demonstrates that the IGF-IR signaling axis is constitutively active in brain-seeking sublines of breast cancer cells, driving an increase in in vitro metastatic properties. We demonstrate that IGF-IR signaling is activated in an autocrine manner as a result of IGFBP3 overexpression in brain-seeking cells. Transient and stable knockdown of IGF-IR results in a downregulation of IGF-IR downstream signaling through phospho-AKT, as well as decreased in vitro migration and invasion of MDAMB-231Br brain-seeking cells. Using an in vivo experimental brain metastasis model, we show that IGF-IR ablation attenuates the establishment of brain metastases and prolongs survival. Finally, we demonstrate that the malignancy of brain-seeking cells is attenuated by pharmacological inhibition with


Background: Pregnancy and allergic disease have both been postulated as T-helper 2 (Th2) phenomena. Thus, the increased propensity of allergic mothers to mount Th2-responses might generate favourab ...


ABSTRACT:The critical discourse on Abraham Cahan's Yekl: A Tale of the New York Ghetto (1896) has given most of its attention to Yekl/Jake Podkovnik, the novel's explicit hero, leaving the character of his wife, Gitl, mostly overlooked. This trend is unfortunate because Gitl is a central and complex character whose role throughout the narrative is essential not only to its plot development, but also to the formation of its meaning as an immigrant novel. As my close reading of the novel demonstrates, by the story's end, the pious Lithuanian "greenhorn" undergoes a process of unexpected and empowering growth, as a woman and as a Jew, which presents a competing alternative to Jake's view of assimilation. While partially observable on the textual surface, this process unfolds most forcefully through the various mechanisms—dress and speech, semiotic components, dialogues of gazes, manipulation of readers' sympathy—that Cahan employs in portraying Gitl's emergence (and Jake's demise). Examining these mechanisms and synthesizing their effects in telling Gitl's story comprise the focus of my discussion, which is framed within Cahan's overall portrayal of women and pays special attention to his craft of characterization, another aspect of Yekl that critics have ignored far too long.


This study attempted to explore the connection between emotional competence and adaptation to life in pupils with ADHD from Southern Taiwan. In addition to analyzing how 32 children with ADHD performed on the scales used, this study was also intended to show the current state of their emotional competence and adaptations to life and understand the correlation between the two. Results of this study reveal the following four key points. (I) The elementary school students with ADHD rated that they have greater emotional competence than their average peers, particularly the competence of 'emotional awareness', a result significantly different from those from previous studies of emotion. (II) The elementary school students with ADHD scored high on the two scales 'Problems with Self-Care' and 'Problems at School' among their self-rated behavioral problems. (III) There is a considerable difference between the self-assessment by the elementary school students with ADHD and the assessment by the outer world. (IV) 'Emotional expression', 'emotional effectiveness' and 'emotional reflection' were able to predict 'problems at school' in the elementary school students with ADHD. Based on these findings, the researcher makes the following suggestions for further exploration and integration regarding this topic.


The paper proposes the territory as the fourth dimension of sustainable development. Research starting from three dimensions of sustainable development economic, social, environmental highlights the difference between the spatial approach and the territorial approach in sustainable development practices. The paper shows that to include in the development approach the morphological (hilly, mountain, plain), functional (metropolitan or non-metropolitan city, cross border region), traditional (port city, financial city, industrial city), government (National strategy, special laws, etc.), governance (formal and not formal network, institutional/ noninstitutional body) aspects, leads to different development results than not including them. This evidence shows to distinguish development practices from sustainable development practices as emerged from recent Territorial Impact Assessment studies in which policies, through the territorialization of the results, guide planning actions: (local) planning actions selected on (general) policy objectives create the conditions for adaptation (about planning) and mitigation (about policies) of human actions on the environment, thus being able to speak of sustainable development.


Objective To evaluate the clinical value of single-layer anastomosis(SLA) in the digestive tract operation. Methods The clinical date of 1 600 cases of SLA and 462 of double-layer anastomosis(DLA) were analyzed. Results The operations on all the 2 062 patiens were performed successfully. The leakage happened in single-layer anastomosis was in 25 (1.56%) cases and stenosis in 3 (0.19%) ; while the leakage happened in double-layer anastomosis was in 8 (1.73%) cases and stenosis in 6 (1.29%). The difference of anastomotic leakage rates between the two methods was not significant (P0.05), but the stenosis rate of the single-layer anastomosis was obviously lower than that of the double-layer anastomosis (P0.01).No anastomotic bleeding developed in all the patients. Conclusions Single-layer anastomosis can not increase the anastomotic leakage rate, but can decrease the anastomotic stennsis and obstruction. It′s a safe, practical and efficient anastomotic method.


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Introduction Crizotinib (Xalkori®) is an ALK inhibitor with proven efficacy in patients with ALK -rearranged advanced non-small cell lung cancer (NSCLC; Shaw AT et al, New Engl J Med 2013;368:2385–9). However, ALK rearrangement is implicated in other types of malignancy, including anaplastic large-cell lymphoma (ALCL) and diffuse large B-cell lymphoma (DLBCL). Here we assess the safety and anti-tumor activity of crizotinib in patients with advanced ALK -rearranged hematologic malignancies enrolled in an open-label phase 1b study (Pfizer; A8081013; [NCT01121588][2]).

Methods ALK -positivity was confirmed by IHC for cases of ALCL; other malignancies required confirmation by FISH, PCR, or sequencing. Patients with brain metastases were eligible if neurologically stable for 2 weeks with no ongoing treatment requirement. Eligible patients received crizotinib 250 mg twice daily. Responses were assessed every 6 weeks using RECIST v1.1 or Revised Response Criteria for Malignant Lymphoma 2007 (Cheson criteria); best overall response was determined by RECIST or Cheson if only one assessment was available, and by Cheson criteria if both were available. Adverse events (AEs) were assessed using CTCAE v4.0.

Results Fifteen patients with advanced ALK -positive hematologic malignancies were enrolled; 14 with ALK -positive ALCL and one with ALK -positive DLBCL. At the data cutoff date of July 15, 2013, treatment was ongoing in 10 patients, and there were five discontinuations (1 due to early death, 1 due to global deterioration of health and 3 due to disease progression). Nine patients (60%) were male, and the median age was 25 years (range 15–37 years). Most patients were white (60%), with the remainder Asian. Two patients (13%) received prior radiation therapy. All patients received prior systemic therapy (median 2 lines [range 1–6]). ECOG performance status (ECOG PS) at baseline was 0 for 3 patients (20%), 1 for 7 patients (47%), 2 for 4 patients (27%), and 3 for 1 patient (7%). Median duration of treatment was 33 weeks (range 0.1–117 weeks). There were 9 confirmed responses (5 complete response [CR] and 4 partial response [PR]), for an objective response rate (ORR) of 60%. Additionally, 1 patient experienced stable disease (SD) of >12 months. Overall, the clinical benefit rate (CBR; CR + PR + SD) was 67%. AEs (all causality) were reported for all 15 patients and were predominantly of grade 1 or 2. The most common AEs were diarrhea (47% of patients), vomiting (47%, including 1 grade 3 event), visual impairment (40%), asthenia (27%), cough (27%), and neutropenia (27%, including 2 grade 3 events). Four patients experienced grade 4 events (abdominal pain, increased creatinine phosphokinase, lymphopenia, and multi-organ failure), and one of these patients also experienced a grade 5 event (central nervous system hemorrhage).

Conclusions Crizotinib showed anti-tumor activity in advanced ALK -rearranged hematologic tumors. The high ORR (60%) and CBR (67%) with crizotinib in this cohort is consistent with the high response rates seen with crizotinib in ALK -rearranged advanced NSCLC, and the safety profile of crizotinib was also similar to previous clinical experience with crizotinib. These data suggest that ALK inhibition can be effective in patients with ALK -positive hematologic malignancy and further investigation may be warranted in this setting.

Disclosures: Gambacorti-Passerini: Pfizer: Research Funding. Off Label Use: Crizotinib is an ALK inhibitor which is indicated for use in ALK-positive advanced NSCLC. This study investigates the use of crizotinib in patients with ALK-positive malignancies other than NSCLC. Braiteh: Pfizer: Membership on an entity's Board of Directors or advisory committees; Pfizer: Honoraria; Pfizer: Research Funding. Taylor: 1. Bayer HealthCare Pharmaceuticals, Inc.: Membership on an entity's Board of Directors or advisory committees; 1. Bayer HealthCare Pharmaceuticals, Inc.: Honoraria. Brega: Pfizer: Equity Ownership; Pfizer: Employment. Paolini: Pfizer: Equity Ownership; Pfizer: Employment. Selaru: Pfizer: Equity Ownership; Pfizer: Employment.

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Coal fly ash (FA) is of high interest as a precursor material for the synthesis of geopolimer binder, representing a waste stream which is readily available from existing industry [1]. FA is not a "standard product" as its physical and chemical properties vary not only from source to source but also over time from the same power station [2]. UK Department of Energy and Climate Change listed 14 coal fuelled power stations operational in 2014, representing 26% of total generated [3]. FA production in UK is estimated at about 6∙106 t per annum, half of which is sent to landfill, whereas about 114∙106 t of FA is available in stockpiles [4], confirming a significant potential availability for FA-based geopolymer concrete production. The suitability of such available ashes has not been thoroughly investigated yet. This paper analyses the factors affecting the reactivity of FA for the synthesis of geopolymer concrete, investigating physical and chemical properties of precursor materials, activator dosages and curing conditions. Detailed characterisation was carried out on thirteen FA sources from the UK. The most important factors affecting the reactivity were found to be the particle size, the loss on ignition (LOI) and the amorphous content of precursor FA. Alkali-activated FA required heat curing and medium to high alkali dosages. Strengths exceeding 70 MPa at 28 days were obtained. Microstructural characterisation with SEM coupled with EDX performed on FA pastes allowed to identify N-A-S-H gel as main reaction product.


In contrast to many regions of the Middle East, where Jewish communities existed at the time of the Prophet and throughout the centuries following his death, the Tamil region of south India and the Indonesian-Malay world lacked such populations. The absence of Jewish communities did not, however, imply a complete unfamiliarity with Jews and Judaism. Rather, their image emerged from a variety of textual sources in lieu of direct encounters. In addition to their depictions in the Qur'an and hadith literature, Jewish figures occasionally appeared in texts produced in these regions' local languages. The Book of One Thousand Questions, composed in Arabic and translated thereafter into many languages – including Javanese, Malay and Tamil – offers a glimpse to portrayals of Jews and Judaism in lands where their actual presence was virtually unknown.


Based on studying the theory of the recreational belt around metropolis,the connotation and extension of the recreational belt around metropolis were analyzed from four aspects of the social effect,the market main body,the region range and the tourism ways.Combining with the domestic city models with the built recreational belt around metropolis,taking tourism resources and tourism traffic as the basic point and the tourism time as the spatial axis,the spatial structure model of the recreational belt around metropolis in Guiyang City was put forward and explained.Relying on the spatial structure model of the recreational belt around metropolis in Guiyang City,the development thoughts of the tourism products in the recreational belt around metropolis in Guiyang City were put forward.


Background: The voltage topography of temporal spikes has two distinct patterns, designated type I and type II; the orientation of the current-dipole source (O-CDS) of type I spikes tends to be oblique, while that of type II spikes tends to be horizontal. The purpose of this study was to identify the effects of the O-CDS of anterior temporal spikes on clinical factors including onset age, seizure frequency, secondary generalization, disease duration, intractability, polytherapy, febrile seizure, hippocampal sclerosis, and neocortical-temporal aura. Methods: We examined the scalp electroencephalograms of 24 patients with temporal lobe epilepsy (TLE) and anterior temporal spikes. A spatiotemporal dipole model was applied to determine the O-CDS of the averaged spikes in each patient. We performed current-source analysis of multiple spatiotemporal dipole models using Brain Electrical Source Analysis software. The patients were divided into two subgroups according to their O-CDS pattern: oblique and horizontal. Clinical factors were compared between the two groups. Results: Sixteen patients were classified into the oblique group, and 8 patients into the horizontal group. A neocortical-temporal aura was more commonly observed in the horizontal group (p<0.05), while drug-resistance tendencies were more commonly observed in the oblique group (p<0.1). Conclusions: The horizontal O-CDS of anterior temporal spikes may be more frequently associated with a neocortical-temporal aura than the oblique O-CDS in TLE. In addition, the oblique O-CDS pattern suggests a tendency toward drug resistance. The findings of this study imply that the oblique O-CDS pattern of anterior temporal spikes may provide additional electrophysiologic information regarding drug-resistant mesial TLE. J Korean Neurol Assoc 29(3):165-171, 2011


Readmission and mortality are the most common and often combined endpoints in acute heart failure (AHF) trials, but an association between these two outcomes is poorly investigated. The aim of this study was to determine whether unplanned readmission is associated with a greater subsequent risk of death in patients with acute dyspnoea due to cardiac and non‐cardiac causes.


Hub site decision is the important basis for a country to carry out the planning and construction of high-speed rail hub.It has an important impact on the development of the high-speed railway construction.And it plays a key role for the hub performance and the long-term gains.Hub site decision is an important part of the sustainable development of the high-speed rail hub.Under the guidance of the sustainable development theory a variety of regional economic development theory was integrated referenced.Through mining the theoretical connotation of green urban group theory,the impact of high-speed rail hub for the development of green urban group was analyzed.With the typical high-speed rail hub features the evaluation system of high-speed rail hub distribution decisions was established.


We combined an expert elicitation and a bottom-up manufacturing cost model to compare the effects of R&D and demand subsidies. We modeled their effects on the future costs of a low-carbon energy technology that is not currently commercially available, purely organic photovoltaics (PV). We found that (1) successful R&D programs reduced costs more than did subsidies, (2) successful R&D enabled PV to achieve a cost target of 4c/kWh, and (3) the cost of PV did not reach the target when only subsidies, and not R&D, were implemented. These results are insensitive to two levels of policy intensity, the level of a carbon price, the availability of storage technology, and uncertainty in the main parameters used in the model. However, a case can still be made for subsidies: comparisons of stochastic dominance show that subsidies provide a hedge against failure in the R&D program. 1Corresponding author. Assistant Professor, La Follette School of Public Affairs and Nelson Institute for Environmental Studies, University of Wisconsin, 1225 Observatory Drive, Madison, WI 53706, phone: +1(608) 265-3469, fax: +1(608) 265-3233, email: firstname.lastname@example.com. 2Assistant Professor, University of Massachusetts, Amherst


QXOH‐Levobupivacaine (LB) is a fixed‐dose combination of 35‐mM QXOH and 10‐mM LB. It was developed for perioperative analgesia because of its long‐acting analgesic effect. The purpose of this study was to evaluate the potential toxicity of QXOH‐LB in beagle dogs in accordance with the Guidance on the repeated‐dose toxicity published by the China Food and Drug Administration. Groups of five male and five female beagle dogs received normal saline, QXOH‐LB (2, 4, and 8 mg/kg, calculated as QXOH), QXOH (2, 4, and 8 mg/kg), or LB (2 mg/kg, equals the concentration of LB in 8‐mg/kg QXOH‐LB group) at the volume of 1 mL/kg once per day for 14 days through subcutaneous injection. No mortality was observed. Dogs in the control group as well as animals treated with 2‐mg/kg QXOH or QXOH‐LB exhibited normal behaviors. Clinical signs of toxicity in dogs treated with 4 and 8 mg/kg of QXOH or QXOH‐LB included decreased activity, unsteady gait, jerks, tremors, vocalization, emesis, ataxia, lateral/sternal recumbency, deep/rapid respiration, and gasping. Additionally, neurological function was found to be affected by QXOH and QXOH‐LB at the doses of 4 and 8 mg/kg. All clinical signs were recovered within 24 h. The no‐observed‐adverse‐effect level of QXOH and QXOH‐LB was considered to be 2 mg/kg. Toxicokinetic data showed that exposure to QXOH and LB increased as QXOH‐LB doses were increased from 4 to 8 mg/kg. There was no evidence of drug accumulation or any effect of gender.


Information technologies (IT) may substitute for routine/manual tasks and complement complex/problem-solving tasks, which can induce bias towards greater demand for skilled labor. This phenomenon of "skill-biased technical change" has important implications for the impact of IT on factor substitution within a firm's production process. Understanding how the substitution and complementarity relationships depend on the skill levels of labor has not been adequately addressed in the IS and economics literature. Using firm-level panel data from California hospitals from 2002-2006, we specified a translog production function and estimated elasticities of substitution between IT spending and skilled vs. unskilled labor. We found that IT is a substitute for capital and low-skilled labor, but is a complement for high-skilled labor. Additionally, the complementarity effect of IT on high-skilled labor is stronger in magnitude than the substitution effect on low-skilled labor. Our results suggest the impact of IT on labor is non-uniform and skill-biased, favoring high-skilled workers over low-skilled workers.


Transportation is an important part of campus life. The need to study the male–female differences in the choice of walking is essential in calibrating a robust travel demand model of the university environment. Subsequently, there is a need for a novel approach in the trip pattern of the university environment. This study assessed the spatio-temporal commuting pattern in three universities in
Nigeria, with a special focus on gender. Information sheets (n = 1500) were distributed to three categories of university in Southwestern Nigeria: private university, State government-owned university, Federal government university. This was backed up with focus group discussions in the selected schools. We assessed the frequency of trips, trip distance, trip pattern, gender and the modal
split of the respondents. Results showed that the female gender accounted for the highest frequency of trips, but the lowest frequency of long-distance trips. The results also revealed that distance, time, travel cost, comfortability and accessibility had a positive influence on the volume of trips. Pearson's Correlation of the variables was done and the Pearson's r value for distance was 0.844 and time, 0.77.
The results showed a strong positive correlation for gender, as compared to the other variables, affecting trip-making. The research showed that gender difference influences the choice of mode and frequency of trips, which are essential variables in travel demand models.


Latest research on the mental health status of children indicates that schools are key providers of mental health services (U.S. Department of Health and Human Services, 2003). The push for school mental health services has only increased as stakeholders have begun to recognize the significance of sound mental health as an essential part of academic success (Adelman & Taylor, 2002). However, while schools are recognized as playing an important role in the delivery of mental health services, it is not well understood about the types of mental health services provided, qualifications of providers, and the link to student outcomes (United States Department of Health and Human Services, 2003). The present study examined Florida school mental health service providers' perceptions about the types of mental health services provided in schools and school mental health service providers' qualifications to provide such services. Additionally, the study investigated the agreement about providers' qualifications to provide mental health services between providers, supervisors, and directors. Finally, this study investigated the perceptions of providers regarding the impact of mental health services on student outcomes. Results revealed that school mental health service providers considered several services, such as family counseling and mental health consultation, to be school mental health services.


Self-regulation is associated with many positive outcomes, but there is limited information about individual difference regarding children's spontaneous use of strategies to self-regulate and the relative success of those strategies. In the current study, we examined whether temperament and gender are associated with self-regulation and explored the types of spontaneous strategies children use during Mischel's delay of gratification protocol. In addition, we investigated whether spontaneous strategy use during the task could moderate the effects of temperament on self-regulation and whether temperament would mediate the effect of gender on self-regulation. Participants were 349 9-year-olds (182 boys, Mage = 9.18, SD = 1.17). Mothers reported on children's temperament and the Delay of Gratification task was used to assess self-regulation. Both temperament and child's gender were significantly associated with children's delay time. Girls were able to delay longer than boys, and children scoring high on activity level were less able to delay. Activity level also mediated the relationship between gender and delay time. Finally, we found an interaction effect between activity level and certain strategies in relation to self-regulatory behavior.


An object of the present invention, by embedding the wiring therein while maintaining smoothness of the surface is suppressed to lengthen the service life peeling or deterioration of the wiring, to provide a substrate for an electronic device to provide a highly reliable electronic device. A first and a second main surface provided, the first main surface an electronic device substrate 100 for which the electrode wiring is formed on the opposite to each other, the glass substrate 101 and the first major surface of the glass substrate 101 auxiliary wiring pattern 200 and the auxiliary wiring pattern, so as to cover the upper layer of (200) the glass substrate 100 with the glass layer 102 of the transparent formed on the surface, and the glass layer 102 formed on the there is a portion through hole (H) exposing the auxiliary wiring pattern 200 is formed, except for the connection area to be exposed from the through hole (H), the glass layer 102, the entire auxiliary wiring pattern 200 since the sealing, there is no risk of deterioration of the auxiliary wiring pattern 200, a reliable and can also provide an auxiliary wiring pattern long life. Further, the surface of the glass layer obtained by vitrification is smooth, and may be one stably uniform the film thickness of the functional layer including an electrode wiring formed on its upper layer.


Respiratory syncytial virus is unique among human viral infections. It is one of the most common viral infections of mankind, and virtually every child is infected by the third birthday. The infection is exquisitely restricted to respiratory mucosa and is frequently associated with bronchial hyperreactivity and development of wheezing. Because of its restricted mucosal immunopathology, RSV has served as an important model to investigate mechanisms of mucosal immune responses and development of mucosal disease after infection. This brief overview highlights the historical landmarks of its discovery and evolving understanding of the mechanisms of immunity, outcome of disease and treatment modalities used for management of infection in humans.


This article introduces a way to draw sound object into Flash 5 and to add it to courseware. It also makes a detailed discussion about different ways to control effectively the sound in the courseware.


The North Atlantic Oscillation (NAO) is the most dominant hemispheric variability affecting the winter climate. It is, however, difficult to predict the NAO on a seasonal time scale. Thus, a better understanding of the NAO is important for improving the accuracy of seasonal forecasts. We investigated the seasonal predictability of the NAO and the zonal mean fields of the stratosphere using hindcasts based on the operational seasonal prediction system of the Japan Meteorological Agency. We found that both the predictive skill and the potential predictability of the NAO index increased from late winter to early spring and that this seasonality relates to high predictability of the zonal mean geopotential height in the stratosphere and near the surface. Analysis of the convergence/divergence of the Eliassen–Palm flux indicates that the high predictability in the stratosphere in late winter results from the large signal of upward-propagating Rossby waves. The downward influence of the predictable signal from the stratosphere to the troposphere was also quantitatively estimated using the approach proposed by Ambaum and Hoskins (2002). The signal of the surface pressure estimated from that of stratospheric potential vorticity is roughly consistent with the actual signal, substantiating the stratospheric contribution to the near-surface seasonal predictability. (Citation: Saito, N., S. Maeda, T. Nakaegawa, Y. Takaya, Y. Imada, and C. Matsukawa, 2017: Seasonal predictability of the North Atlantic Oscillation and zonal mean fields associated with stratospheric influence in JMA/MRI-CPS2. SOLA, 13, 209−213, doi:10.2151/sola.2017-038.)


Summary. .

Plants of Polygonum lapathifolium were grown either in a glasshouse or outside, at a high or a low level of mineral nutrition, and either with or without competition from barley. The viability and percentage emergence of seedlings from germinated seeds (planted in sterile compost) were higher with seed from glasshouse-grown plants. High nutrition increased plant weight, seed production and seed weight, and also increased seedling emergence. Competition reduced plant weight, but had only a small, non-significant, effect on seed production. Seed from plants grown with competition had a greater percentage seedling emergence from germinated seeds.


The shape of the honeycomb core must be considered in the analysis of the problem of electromagnetic wave scattering in a honeycomb sandwich structure at high frequency. The three-layer sandwich structure has the characteristic of having a very small dielectric region with respect to its entire volume, since it has a structure in which the upper and lower skin sandwich between them a honeycomb core which contains many honeycomb-shaped holes. On the other hand, volume integral equations have the advantage of discretizing only the dielectric region, since only the polarized electric current of the dielectric region is an unknown. Thus, electromagnetic wave simulation of the three-layer honeycomb sandwich structure by using volume integral equations is considered to be an effective means for large-scale precision analyses. This paper reports a numerical computing method that takes account of the shape of the honeycomb core, applying three-dimensional volume integral equations to the electromagnetic wave scattering problem of the three-layer honeycomb sandwich structure, and the results of code verification by means of the optical theorem and its reciprocity are presented. In addition, the effectiveness of the proposed numerical computing method is shown by identifying the effects of the honeycomb core on the electrical field intensity distribution inside the skin. © 2001 Scripta Technica, Electron Comm Jpn Pt 2, 84(10): 24–33, 2001


The Pethik Pari tradition is a tradition of the Javanese farming community. This tradition is in the form of a series of selamatan ritual performed as a form of gratitude of the farmers to God Almighty for abundant sustenance through good harvests. The Pethik Pari ritual used to be carried out by Dukuh Dempok Village farmers individually in their homes by simply carrying out a simple slametan. But now, the ritual procession is changing and carried out jointly by farmers in the fields by carrying out slametan, Wayang's performances, and fishing together in the rice fields. With the change in the implementation of the ritual procession, making the Pethik Pari ritual a re-establishment of the individuality of peasants in Dukuh Dempok Village. The ritual tradition of Pethik Pari itself, is also a symbol of the Javanese peasant community that there is a belief in the existence of Dewi Sri as a goddess of prosperity. This research uses descriptive qualitative method with a case study approach. Data was collected through in-depth interviews with informants from the head of the farmers' groups and Dukuh Dempok Village farmers. The focus of this study was to determine the re-establishment of the individuality of farmers in Dukuh Dempok village, Wuluhan, Jember, East Java.


The aim of this narrative review is to explore the relationship between visual snow syndrome (VSS), migraine, and a group of other perceptual disorders.


Transient stability of the MicroGrid in which the micro sources use the P-f & Q-V droop control and PQ control was investigated. The impacts of motor load, different types of faults and the different locations of faults on the transient stability of the MicroGrid are presented in this paper. And the relation between the proportion of motor load and Fault Clearing Time (FCT) was explored.


The general situation of BDS,its strain,and the metabolic types of the bacterium,were reviewed.The focal point of the introduction was the different metabolic types and the research approach of BDS.This could be used for the indurstrial application renference of BDS in our country.


This is an interesting and valuable article that presents an overview of the current status of using digital support tools (models, data, visualisation, etc.) in hydrology university education in USA. Results from surveys and workshops carried out with hydrology university educators are presented that indicate the requirements and critical steps in moving forward towards a community-based development and sharing of new hydrology education curricula with associated digital supporting tools. The use of such supporting tools is identified to be more widespread at graduate levels, but there is a


This thesis is a research about the prophetic office of Christ ofDr. Hyung Ryong Park(1897-1978) who was a Reformed orthodoxy theologian in Korea. The purpose of this thesis is to present the unique Mediator and the absolute Saviour of Christ Biblically, soteriologically, dogmatically, and practically by interpreting the triple office(munus triplex) of Christ according to H. R. Park. They are a substantiation and an illustration of the unique work of the mediator. ``Office`` implies a representative capacity, understood here as a ministry, a charge or a function into which Christ is officially inducted as mediator, with a dual reference to the Father and to humanity. As such the offices interpret the name of Christ` who, as Mediator, is anointed in a messianic capacity for his work: to proclaim divine truth as prophet, to intervene as priest and to rule as king. According to H. R. Park, Christ reigns over His kingdom through His kingly office. His kingdom can be divided as three kingdoms, namely the kingdom of the grace(regnum gratiae), the kingdom of the power or the nature(regnum potentiae sive naturae), and the kingdom of the glory(regnum gloriae). ``Regnum gratiae`` of Christ is a spiritual kingdom governed by God-man, Mediator through His Word and Spirit. It is almost the same as church which is allowed by God to expand the kingdom of God. ``Regnum poten tiad of Christ forms a physical and moral system outwardly. The Kingship of Christ has priority over the other offices. As king Christ implements his rule through the priestly office exercised at the cross, the empty tomb and in the eternal intercession as great High priest. This kingdom will finish its mission when the purpose of redemption is accomplished. ``Regnum gloiae`` of Christ is a kingdom that will be completed after the ``regnum gratiae`` of Christ and ``regnum potentiae.``


This study represents one of the largest clinical case series' evaluating long-term outcomes following surgical fixation of tibial plateau fractures over a 10-year follow-up. The primary aim is to evaluate the incidence of TKR and risk-factors associated with poor outcomes.

 Patients receiving surgical fixation of tibial plateau fractures between 2008 – 2012 were included. Those requiring arthroplasty or endoprosthesis post-injury were excluded. PACs was used to analyse case notes and radiographic imaging. Articular reduction and alignment (mPTA) were measured using pre-operative radiographs. Comparisons were made with radiographs post-fracture union (6-weeks to 6-months), assessing fracture reduction maintenance. Long-term outcomes were assessed for patients receiving imaging thereafter. Patients were checked using the Scottish National Imaging Archive.

 130 patients presented various fractures (Schatzker I-III n = 78, IV n = 12, V n = 9, VI n = 29) and 2 open-fractures. 32 patients required further surgery, 13 required multiple operations - resulting in 47 operations. These included metalwork removal (n = 28, 21.5%), TKR (n = 12, 9.2%), washout for infection (n = 3, 2.3%), osteotomy (n = 2, 1.5%), sequestrectomy (n = 1, 0.8%), and above knee amputation (n = 1, 0.8%). ≥ 2mm articular reduction was maintained in the majority (84%); however, good articular reduction did not prevent progression to arthroplasty (average step 1.4mm in TKR versus 1.8mm in non-TKR). Good alignment correlated with favourable outcomes - average mPTA being 90.8° in non-TKR versus 93.5° in TKR.

 These findings support previous literature in this field demonstrating that malalignment, rather than articular depression, increases the risk for post-traumatic arthritis requiring arthroplasty. The incidence of TKR after tibial plateau fracture fixation at 10-years was 9.2%.


Background: Pentoxifylline, a valuable medication with promising clinical characteristics and considerable profile of safety is used in many conditions namely chronic kidney diseases (CKD). However, the decision to prescribe pentoxifylline for anemia in CKD should be based on evidence accrued from randomized controlled trials (RCTs). Yet, substantial heterogeneity exists in studies performed to evaluate pentoxifylline therapy, particularly in relation to classification of patients, the different quality and research design, sample size, baseline parameters, clinical outcome measures, and definition of endpoints and clinically meaningful improvements. As a result, assessment of pentoxifylline in treating anemia of CKD by conducting a systematic review and meta-analysis of the published relevant clinical studies seems rational and promising. Methods: The present systematic review was done in accordance with the PRISMA guideline for systematic reviews and meta-analysis. Peer-reviewed RCTs with at least four weeks of follow-up were including in the meta-analysis. Online databases (PubMed/Medline, ISI Web of Science, Embase, and Scopus) were searched to December 2017 using selected MeSH terms related to the studied topic. Data was extracted independently by two reviewers using a standard form and then cross-checked. Statistical analyses were carrying out with Stata Software, version 7.0 (Stata Corp., College Station, TX, USA). P value of less than 0.05 was considered statistically significant. Data are presented as standard mean difference (SMD) and confidence interval (CI) 95%. Results: According to the predefined criteria, a total of ten studies (parallel group or cross-over trials, and case-control studies) were included and screened for data extraction by two reviewers, separately. The preliminary results extracted from meta-analysis have shown that pentoxifylline can significantly increase transferrin saturation (SMD: 0.348; CI95%: 0.008, 0.688), but there were no conclusive effects of pentoxifylline on hemoglobin (SMD: 0.171; CI95%: -0.390, 0.732), hematocrit (SMD: 0.466; CI95%: -1.426, 2.357), ferritin (SMD: -0.010; CI95%: -0.346, 0.326), and administered dose of erythropoietin (SMD: 0.114; CI95%: -0.232, 0.460), in pooled analyses. Conclusion: There is uncertainty about therapeutic effects of pentoxifylline on anemia of CKD patients. Since these patients has many diverse complications and receive multiple drug therapy, the results of such meta-analysis regarding outcomes of pentoxifylline therapy may have beneficial effects on rational drug prescription. Abstract


In 1988 the development of a computerized tutorial program for education statistics was started at the University of Amsterdam. In this article, this program will be described. Also several other aspects of this computer program will be discussed. An important part of the article will focus on a description and evaluation of the program itself, as well as on experiences of teachers and students. We will also pay attention to the background of the program: reasons for developing the program, the development process itself, the way the program was set up, the area of statistics is addressed by the program, and how the program works.


Abstract: Terrorism has stricken fear in the hearts of many people across states and nations. To predict future patterns and gain past insights, in this report we aim to analyse the GTD dataset for various terrorist attacks and try to incorporate meaningful inferences from it along with bringing new novel pat- terns and relations undiscovered till now using various machine learning models like random forest classifier,bagging,k-NN,ANN after applying some initial cleaning and exploratory analysis on the data using classic visualising techniques like wordcloud, heat maps,geographical graphs and more.


A simple, fast and precise Reverse Phase High Performance Liquid Chromatographic ( RPHPLC) method developed for the determination of Donepezil Hcl tablets, C18 column 250mm x 4.6mm(l x d) in reverse phase isocratic mode of separation with mobile phase methanol : 0.02m phosphate buffer : Triethylamine (60:40:0.5)% v/v were used. The flow rate was 1ml/min. Linearity for Donepezil Hcl were in the range of 50mcg/ml 150mcg/ml. Amount found of Donepezil Hcl in Aricept 5mg, Aricept10mg, Dopezil 5mg tablets were 5.0072mg/tab, 10.01mg/tab and 5.01mg/tab respectively. Percentage recovery obtained was 100.53%, 100.24% and 100.34%. The proposed method is accurate, precise, selective and rapid for the estimation of Donepezil Hcl in tablet dosage.


Buddhism was not too concerned about the progress of Christianity in South Korea (hereafter Korea) until approximately in the 1990s. It simply and silently co-existed despite possible conflicts that could have presented themselves because of criticism about Buddhism, voiced by some Christ ians. The calmness of this typically Buddhist response to criticism naturally played an important role in the fact that religious harmony could exist within the confines of a common civil order in the Korean society. However, this situation has shifted radically when, four years ago, the present government of Korea took office. The current president of Korea is a Christian. He has been brought up in a Christian family, and he has also served as an elder for a mega-Presbyterian church, in Korea referred to as the Somang (Hope) Church. In his cabinet, most ministers have a Christian background and only a few come from a Buddhist background. Evidence abound that his policies are flawed by Christian favouritism. Korean Buddhists have traditionally adopted a policy of silence in matters which have to do with experiences of religious discrimination. However, at this time, their response is changing to one which unanimously opposes the current policy of religious favouritism as practiced by the President. A strong feeling of unity is emerging among Buddhist clergy and lay Buddhists, especially the socially engaged Buddhist intellectuals who oppose the present government policy, and a strong political force is emerging alongside this unity. A key issue which provides a focus for this criticism is the question of religious education in private secondary schools. Socially engaged lay intellectual Buddhist groups, with the support of the Buddhist clergy, are questioning the propriety of government involvement that creates conflicts between Buddhists and Christians.


The superfamily of 2‐oxoacid dehydrogenases is important in metabolic pathways, including human and bacterial. The pyruvate dehydrogenase complex (PDHc) is at the intersection of glucose metabolism and the citric acid cycle and comprises multiple chains of three components: thiamin diphosphate dependent E1, lipoylated E2 and the FAD/NAD+‐dependent dihydrolipoyldehydrogenase E3. We are investigating primarily the E1 and E2 components, the latter produce acylCoenzyme A from the 2‐oxoacid reactants. Among the E2 components, both the octahedral symmetry bacterial enzyme, and the icosahedral human enzyme have multiples of three chains; we are presenting experiments to understand the need for multiples of three chains. Expt. A. We have made two types of E2 constructs of PDHc from Escherichia coli: one defective in posttranslational lipoylation by the ligase, the other defective in the synthesis of acetylCoenzyme A. While neither construct is active by itself, their complementation produces active enzyme. Expt. B. We use a combination of NMR and mass spectrometry to define whether the binding sites on E2 for the E1 and E3 components are identical or non‐identical. The results of both experiments on the Escherichia coli PDHc point to the likelihood that during each turnover, the three chains have different roles. The model can also be readily extrapolated to the human enzymes. Supported by NIH‐GM‐050380.


. In this study, we reveal an approximate linear relation for Bessel functions of the first kind, based on asymptotic analyses. A set of coefficients are calculated from a linear algebraic system. For any given error tolerance, a Bessel function of an order big enough is approximated by a linear combination of those with neighboring orders using these coefficients. This naturally leads to a class of ALmost EXact (ALEX) boundary conditions in atomic and multiscale simulations.


The article considers the analytical review of digital technologies (smart farming) in agro-industry. Such digital technologies include computer programs for calculating the farm animal diet, their advantages and disadvantages are given. The analysis and disadvantages of foreign robotic systems for feeding animals are presented. The results of correlation and regression analysis of the impact of the herd size of farm animals on labor input for their feeding are presented. The impact of the number of feed loading cycles in the hopper and its capacity on the uneven feed distribution by the "Free Stall Feeder" robotic feed distributor using the Mathcad 15 program is shown.


OBJECTIVE: To present a case of takotsubo cardiomyopathy in a patient with status epileptic.
 BACKGROUND: Takotsubo cardiomyopathy describes the ballooning of the apex of the heart, transiently creating a systolic dysfunction mimicking myocardial infarction and may be a rare, potentially fatal sequela of seizures thought to contribute to sudden death in epilepsy (SUDEP).
 DESIGN/METHODS: A 62-year old female with a past medical history of hypothyroidism was brought to our emergency department by ambulance after a 20-minute witnessed generalized seizure, which was aborted with intramuscular midazolam. Cardiac troponins rose to 10.89 ng/mL within 12 hours, and cardiac catheterization revealed apical ballooning without occlusive coronary artery disease. The patient's ejection fraction dropped to 20[percnt], systolic blood pressure dropped to 66/36, response to IV fluid bolus. Blood pressure stabilized after 5 days follow up Echocardiogram showed EF 60[percnt] and normal left ventricular function.
 RESULTS: Takotsubo cardiomyopathy in seizure (TCS) has been attributed to massive catecholamine surges, possibly due to overstimulation of the insular cortex. Patients may be unaware of chest pain in the post-ictal state, causing this phenomenon to be overlooked. TCS may also be caused by β-adrenergic receptor hypersensitivity due to denervation from repeated seizures, leaving it vulnerable to catecholamine surges. TCS patients are likely to be younger in age, more often male, and have higher rates of cardiogenic shock and recurrence. TCS may present up to 72 hours after seizures, and may contribute to SUDEP by causing arrhythmias and shock. To date, no specific therapy or guideline has been developed to treat TCS; only serial EKG, echocardiography, and troponins in the post-ictal period can detect this phenomenon early enough for supportive therapy.
 CONCLUSIONS: TCS is a rare and lethal adverse effect of seizures that warrants heightened vigilance for close cardiac monitoring.
 Study Supported by: Disclosure: Dr. Khan has nothing to disclose. Dr. Mirchandani has nothing to disclose. Dr. Pushchinska has nothing to disclose.


IN the previous pages an attempt was made to show why the west side of the valley contains a prairie formation, and the east side a forest formation, and why the coniferous type of forest prevails rather than a broad-leaved deciduous type. A plot will now be presented in detail to show why in the forest formation there are some areas altogether without trees. In order to reach definite conclusions, a limited area was selected to represent the whole forest area of the valley. This area, comprising about 250 square kilometers, was mapped, and the conditions for forest growth were determined (map). The relation of this area to the whole valley is shown in fig. 3. It lies at the northeast end of Flathead Lake, and includes a portion of the main valley on the east side of the Flathead River at the head of the lake, the low end of the Mission Range of mountains, and a portion of Swan valley. In this area are found many types of topographic diversity, from Flathead Lake (890 m) to the highest point (about I372 m) in that part of the Mission Range which is included in the map. No detailed study was made in the higher Swan Range east of the valley, though some conditions of tree growth were noted in these mountains. As shown by the map, five distinct edaphic formations were found: meadow (hydrophytic), Engelmann spruce (meso-hydrophytic), western larch-Douglas spruce (mesophytic), Douglas spruce-bull pine (meso-xerophytic), and prairie xerophyticc).


The paper emphatically elaborates the process and method of realizing semantic annotation for domain data based on the CSSCI conceptualization which constructed before. The essence is that extracting the academic resource instances from CSSCI data under the guidance of the object-oriented knowledge organization model, setting values for properties of the instances by methods of directly extracting based on relational data model, directly statistic calculating assisted by TF-IDF algorithm, synthesis algorithm combined criterion weighting with formal concept analysis and so on, discovering and analyzing semantic association between instances, so as to integrate all CSSCI academic resources into a huge knowledge map based on ontology and to support the knowledge retrieval and citation analysis.


The title compound, [PtRe(C5H5)(C8H6)(C18H15P)2(CO)2]·0.5C4H10O, represents the first example of a structurally characterized μ-vinylidene Re–Pt complex, and was obtained as a product of the addition of [Pt(PPh3)]2 to (η5-C5H5)(CO)2Re=C=CHPh. The two metal atoms are bridged by the μ-phenylvinylidene ligand. The central fragment of the molecule is an almost planar methylenedimetallacyclopropane RePt(μ-C=CHPh) system. The Re atom is bonded to the η5-C5H5 ring and two CO groups, one of which has a tendency to a weak semi-bridging interaction with the Pt atom. The distorted square-planar coordination of the Pt atom is formed by the two P atoms of the PPh3 ligands, and by two C atoms of the C=CHPh ligand and one of the CO ligands. The solvent molecule is disordered equally over two positions.


This paper first briefly overviews national and international legislative frameworks that basically influence the activities of the Hungarian Ministry for Environment and Regional Policy (MERP) in the field of environmental information management. Then it is shown how Hungarian efforts to improve the environmental information system connect to the EU's EIONET network. The paper secondly aims to indicate the large scope of tasks to be undertaken for setting up a standard application for the MERP and its regional authorities. It is illustrated how the ESRI products provide a reliable basis for GIS processing of related data. The Integrated GIS of the Ministry was funded by the Phare assistance programme, and was implemented within the framework of a combined project. The Arc-Info/Arcview/Oracle environment was selected for realisation of the project in a client-server architecture. It is composed of three sub-systems as follows: environmental protection, nature conservation, and a register. The system serves as an inventory for analysis, modelling and decisionmaking concerning the issues of environmental protection and nature conservation. Thirdly, the paper offers a brief outlook and indicates the importance of collaborating with data owners, communicating information to the public on the state of the environment, and what can integrated environmental and economic information systems mean from the environmental stakeholders' point of view. LEGAL FRAMEWORKS AT INTERNATIONAL AND NATIONAL LEVEL EU-Legislation The main elements of EU-legislation influencing the activities of the Ministry for Environment and Regional Policy in the field of environmental statistics and information are as follows: • 94/808/EC Council Decision of 15 December 1994 adopting a 4-year development programme (1994- 1997) relating to the environmental component of community statistics (under constant renewal); • Council Regulation (EEC) 1210/90 of 7 May 1990 on the establishment of the European Environment Agency and the European Environment Information and Observation Network of the Council of the European Communities (modification is under preparation); • 93/464/EEC Council Decision of 22 July 1993 on the framework programme for priority actions in the field of statistical information 1993 to 1997 (renewal is constant); • 85/338/EEC Council Decision of 27 June 1985 on the adoption of the Commission work programme concerning an experimental project for gathering, coordinating and ensuring the consistency of information on the state of the environment and natural resources in the Community; • Practical Steps towards the implementation of the Communication from the Commission to the Council and the European Parliament on Directions for the European Union on Environmental Indicators and Green National Accounting (COM(94)670 final). European Environmental Information Systems DETERMINE, SZENTENDRE 1998 148 Hungarian Legislation The major components of Hungarian legislation concerning MERP activities in the field of environmental statistics and information management with some specifics and explanations can be summarised as follows: • Cabinet Decree of 2339/1996. (XII. 6.) on the Tasks of the Development of an Environmental Information System in the Field of Environmental Statistics. Following an earlier Cabinet Decree, environmental data systems were overviewed from an OECD and EU requirement point of view, and a proposal prepared for the Government on the development of an environmental information system which (in the framework of the Integrated Environmental and Economic Information System): • is able to merge environmental data systems; • can relate human activities, the state of the environment and societal responses, and target areas of environmental policy; • combine results in an environmental-economic database which can provide valuable usable information for decisionmaking, environmental policy, and the general public. In the Annex to this Decree, an implementation plan was included which covered a 6-year period, and aims to seek the improvement and satisfaction of OECD/EU data demands, in harmony with Hungarian tendencies and objctives. In order to perform these tasks, it is necessary to develop both the field of statistics and the other components of the environmental information system. The huge amounts of basic data that constitute environmental statistics come from outside statistical sources such as environmental monitoring and measurement systems, scientific experiments, and different kinds of inventories etc. It is necessary to ensure this development becomes inseparable from the technical and methodological evolution of data collection and information systems. • National Statistical Survey Programme (NSSP) This Programme is updated annually by a Government Order. Within the NSSP, there are several environment-related data collections (direct or indirect) supervised by the National Statistical Office and Ministries. • Act LIII of 1995 on the General Rules of Environmental Protection This Act contains three sections that deal with environmental information systems and the provision of information (see Annex for detail). MERP STRATEGY FOR THE DEVELOPMENT OF AN ENVIRONMENTAL INFORMATION SYSTEM IN HUNGARY The MERP's long-term concept is to establish a multi-targeting and multi-objective unified environmental information system. What exactly does this mean? Firstly, it does not mean the establishment of one enormous system, but rather the rearrangement of existing sub-systems and management of their imminent and artificial contradictions and counteractions. In order to reach this ultimate target, the following strategic steps must be taken (see also Figure 1). • First, a national centre linked to well-equipped regional centres within regional authorities should be established (to this end a pilot project financed by Phare was launched and completed in 1996, see below for further detail). • Secondly, the national centre should serve as a repository of all central databases and main contact points to the international community. In Hungary, this contact point is represented by the UNEP/GRID Budapest office that was inaugurated in April 1997. • Thirdly, institutional settings should be seen in relation to information systems and procedures already in use, or planned by other ministries and other relevant organisations, and institutes. European Environmental Information Systems DETERMINE, SZENTENDRE 1998 149 MERP


This book is from the "Statistics in the Social and Behavioral Sciences" series of Chapman and Hall/CRC, which has quite a broad scope. The book's preface states its goals as follows: "The goal of this book is to provide [...] a comprehensive resource for the conduct of multilevel modeling using the R software package." "Our goal is to provide you with a guidebook that will serve as the launching point for your own investigations into multilevel modeling". The content suggests that the book is written for R novices with weak statistical background – nothing is taken for granted except for means, variances, correlations, and perhaps the normal distribution. For this audience, the "own investigations into multilevel modeling" are a real stretch. It will be discussed at the end of this review, which audiences might benefit from the book for which purposes.


Introduction: Anencephaly is a neural tube defect (NTD) caused by a failure of closure in the cranial neuropore between the third and fourth week of gestation (23rd and 26th embryonic day),resulting in the absence of a major portion of the brain, skull,and scalp. Materials and methods:The present study has been conducted on 14 cases of anencephaly obtained from the Department of OBG over a period of three years. Aims and objectives: To study the correlation of maternal factors on the incidence of anencephaly. Results: Discussed in the Paper Conclusion: Better knowledge of unexpected fetal loss is the promise for better parental counselling and for prevention of recurrences. Understanding and identifying the risk factors associated with anencephaly in our population, allows approaches to avoid them and thereby lower the incidence of anencephaly in our population.


Objective Using autologous fat autotransplantation to restore the volume of face and improve facial recontouring and aging face.Methods Fat globules harvested by suction with injection syringe.After purification was injected into recipient areas on the face,such as temple,cheek,nasolabial fold,circum-orbit,subdermal wrinkle,etc with an amount of 30% over.Results Majority of autotransplantations are performed once and get saticfactory effect,histocompatibility,with none infection?lump?colliquation.Aging face is improved.The curative effect is sure.Conclusion Local injecting transplatation of autologous fat is effective and can be used single or auxiliary.


SYNOPSIS

Cortical features were analyzed in successive samples of continuously growing stock cultures of amicronucleate strains GL-C and GL-I, and in micronucleate strain WH-6 (syngen 1, mating type I). Thirteen successive samples of strain GL-C, representing a time span of 111 months, 5 samples of WH-6 (43 months) and 2 samples of GL-I (1 month) were examined. The observed range of commonly expressed ciliary row numbers (corticotypes) was 16–20 rows in strain GL-C, 15–20 in strain GL-I, and 16–20 in strain WH-6. These ranges remained constant through time within each strain. The individual samples each included all or a large part of the total range observed in the strain, but the relative abundances of different corticotypes within this range shifted through time. The shifts appeared random, with no discernible trends.

Mean contractile vacuole pore (CVP) position and number of CVP meridians were assayed in the 2 "GL" strains. Mean CVP position was an apparently stable character, with only slight fluctuations through time, while the distribution of number of CVP meridians was somewhat less constant. The CVP parameters of strains GL-C and GL-I were considerably different, and both of these strains were very different from the GL strain which had been studied by Nanney. In fact, these 3 "GL" strains have, among them, virtually the entire gamut of known CVP characteristics. The possible significance of these wide differences among strains presumed to be closely related is considered in the Discussion.


Sex attractant traps containing a blend of (Z)‐11‐hexadecenal (Z11‐16:Ald) and (Z)‐11‐hexadecen‐1‐ol acetate (Z11‐16:Ac), in a 10:1 ratio, yielded the highest captures of male Acrolepiopsis assectella Zeller moths in comparison with Z11‐16:Ald alone or various mixtures of Z11‐16:Ald, Z11‐16:Ac and Z11‐16:OH. Our results at Wageningen could be confirmed by similar findings obtained at other locations in Europe.


Current scientific works on parenthood issues agree in thinking of the family as starting with the child, and not with filiation and alliance (marriage). This idea is already found, at the beginning of the xx th century, in the works of the anthropologist Elsie Clews Parsons. She developed, through her parental contract proposal, a theory of parental responsibility that leaves men and women free (or not) to cooperate within the family, to define the roles by themselves and for themselves, provided that the children are raised according to minimum standards as per norms governed by the State. Her avant-garde papers fell, alas, into oblivion. However, they remain very topical and allow us to reconsider, a century later, not only the advances in, but also the recurrences of contemporary debates about the family. In addition to her ideas on parenthood, this article aims at introducing Elsie Clews Parsons and her role in the history of American anthropology and feminist studies.


Neutropenia remains a major risk factor in the development of invasive aspergillosis (IA) after HSCT. In this issue of Blood , Hartigan and colleagues illustrate that lack of expression of CCR7 on hematopoietic and progenitor cells alters their proliferation and differentiation potential and the


Background and Aim: Assessment of total energy expenditure (TEE) is essential for recommendations for dietary intakes and physical activity in patients with diabetes mellitus as well as healthy people. However, few reports have shown TEE in patients with diabetes, particularly in Asian countries. Therefore, we evaluated accurate TEE by doubly labeled water (DLW) and physical activity level (PAL) in Japanese patients with diabetes mellitus. Methods: We planned to recruit sixty patients with type 2 diabetes and sex- and age-matched twenty nondiabetic subjects as the CLEVER-DM Study at a single university hospital. The current presentation is a part of this study with forty-one patients with type 2 diabetes (DM, 69.9 years, men/women: 23/18) and nine patients without DM (non-DM, 67.2 years, men/women: 2/7). TEE was measured over 14 days by DLW method and PAL was calculated as TEE divided by resting energy expenditure assessed by indirect calorimetry. Results: The numbers of DM patients treated with insulin, oral hypoglycemic agents, and diet/exercise were 13 (31.7%), 20 (48.8%), and 8 (19.5%), respectively. Mean (standard deviation [SD]) level of HbA1c was 6.9 (0.8)% for DM and 5.5 (0.4)% for non-DM (p Conclusion: TEE was comparable between DM and non-DM groups among Japanese. Disclosure K. Kondo: None. K. Morino: Research Support; Self; Astellas Pharma US, Inc., AstraZeneca, Sunstar Inc., CMIC Pharmascience, Kowa Pharmaceutical. S. Tanaka: None. K. Fuse: None. A. Ohi: None. M. Kurihara: None. M. Sasaki: Other Relationship; Spouse/Partner; Terumo, Nestle Japan. F. Katsukawa: Speaker9s Bureau; Self; Merck Sharp & Dohme Corp., Sanofi, Astellas Pharma US, Inc. H. Maegawa: Speaker9s Bureau; Self; Astellas Pharma US, Inc.. Research Support; Self; Astellas Pharma US, Inc.. Speaker9s Bureau; Self; Mitsubishi Tanabe Pharma Corporation. Research Support; Self; Mitsubishi Tanabe Pharma Corporation. Speaker9s Bureau; Self; Sanofi. Research Support; Self; Sanofi. Speaker9s Bureau; Self; Nippon Boehringer Ingelheim Co. Ltd.. Research Support; Self; Nippon Boehringer Ingelheim Co. Ltd.. Speaker9s Bureau; Self; Daiichi Sankyo Company, Limited. Research Support; Self; Daiichi Sankyo Company, Limited, Takeda Pharmaceutical Company. Speaker9s Bureau; Self; Takeda Pharmaceutical Company, Novo Nordisk A/S, Eli Lilly and Company.


B is a deadly disease caused by the toxins produced by the bacterium Clostridium botulinum. The botulinum toxin is a potent neurotoxin that impairs nerve function, including those of the diaphragm, leading to paralysis. When the nerves to the diaphragm are paralyzed, the affected animal stops breathing and will die as a result. C. botulinum is an anaerobic (lives without oxygen), gram-positive, sporeforming bacterium. The toxin produced by C. botulinum is one of the most potent toxins known to science. The Clostridium family is known for causing rapid, severe, and deadly diseases, including botulism, tetanus, blackleg, malignant edema, etc. Sometimes the onset of clostridial disease is so rapid that no clinical signs are noted, and the owner simply finds the animal dead. The botulism toxin blocks the release of acetylcholine in the neuromuscular junction. Acetylcholine is a neurotransmitter, which transmits information from the nerve cell to the muscle cell. It is released in the neuromuscular junctions (the space where nerves communicate and stimulate muscles), and it enables muscle contraction; therefore, without acetylcholine, the muscles will not contract. A very important muscle in any mammal's survival is the diaphragm, which, when contracted, enables breathing. Ultimately, without acetylcholine, a horse infected with botulism will die of respiratory failure and asphyxia, due to the paralysis of the diaphragm. There are seven types of botulism recognized (A, B, Ca, Cb, D, E, F, and G), based on the antigenic specificity of the toxin produced by each strain. Types A, B, E, and F cause human botulism. Types A, B, C, and D cause most cases of botulism in animals. In horses, type B botulism is responsible for more than 80% of the cases. The bacterium and its spores are widely distributed in nature. They are found in soil, sediments of streams and lakes, and in the intestinal tracts of fish and mammals. The bacteria will produce toxins under conditions of decaying plants and animals. A horse can get botulism in three ways: • By consuming forage or feed containing the bacteria, which will then produce the toxins in the intestinal tract (more commonly found in foals, known as shaker foal syndrome, or toxicoinfectious botulism). • By consuming feed or forage containing the pre-formed toxins of C. botulinum (known as forage poisoning). • Through wounds contaminated with the bacteria, generally puncture wounds. Wound borders will close, providing an anaerobic environment, which is a favorable condition for the bacteria to produce the toxins.


Using a multisectoral model and data from the Supply and Use Tables, this article estimates the COVID-19 multiplier effects of tourism on gross domestic product (GDP), total employment, and trade balance of the Greek economy. The results indicate that a—not-unexpected—decrease of international travel receipts in the range of 3.5 to 10.5 billion euros would lead to a decrease in GDP of about 2.0% to 6.0%, a decrease in the levels of employment of about 2.1% to 6.4% and an increase in the trade balance deficit of about 2.4 to 7.1 billion euros, respectively.


Some policymakers believe that academic R&D generates insufficient economic benefits. However, they often exclude the long-term and multi-dimensional impacts that are mediated through the activities of companies, students or policymakers. This case study, which is mainly interview-based, traces and characterises such impacts applying the technological innovation systems approach to the case of a physics professor. Multi-dimensional impacts are revealed in the areas of catalysis, biomaterials and research policy. Impacts on the development, social capital and search processes are continuous and cumulative, while impacts on resource mobilisation and legitimation follow upon these. Entrepreneurial experimentation and market formation are impacted in later stages, sometimes with decade-long time lags. The impact is often subtle, deeply intertwined with the action of others, and it unfolds in sequences of impact. Implications are drawn for research policy, emphasising the importance of accounting for indirect impacts in order to understand the full effect of academic R&D.


The success of endodontic therapy requires thorough knowledge of the internal and external dental anatomy and its variations. The internal anatomy of the maxillary central incisor is well known and usually presents with one root and one canal system. This case report describes an endodontic treatment of a maxillary central incisor with one root and two canal systems, demonstrated by radiography and computerized tomography examinations.


Although transmission at postganglionic adrenergic nerve endings can be blocked by a wide variety of guanidine derivatives (Mull, Egbert & Dapero, 1960; Boura, Copp, Green, Hodson, Ruffell, Sim & Walton, 1961; Barron, Bavin, Durant, Natoff, Spickett & Vallance, 1963; Augstein & Green, 1964), considerable specificity is often found among guanidine derivatives with closely related structures. The adrenergic neurone blocking activity of N-aralkylguanidines in cats has been shown (Fielden, Green & Willey, 1965) to depend markedly on the nature of the alkyl side-chain, on substitution in the aromatic nucleus, and on the stereochemistry of individual pairs of optical isomers. In the present paper we show that N-aralkylguanidines display a similar pattern of specificity when their adrenergic neurone blocking activity is assessed in mice by the production of ptosis, and we have attempted to relate this specificity to some biochemical action.


This study was conducted to analyze firm survival rate and impact factors of survival of Foreign-invested Companies in Korea which is between 2006 and 2017. An empirical analysis of the survival factors of firms used explanatory variables such as characteristics of the and 3 firm dummy and 2 firm factors, financial variables of 3 profitability and 3 stability factors. The Kaplan-Meier method was chosen to perform analyses on the survival rates, Cox Proportional Hazard Model took to conduct on the impact factors. As a result of the impact factors of Foreign-invested Companies survival, Ownership (OS), Labour (NE ) of characteristics of the firm had positive effects. The Gross Sales Profit (GSP), Net Profit (NP ) and Operating Profit (OP ) of the financial characteristics had a positive effect. Additional Asset (LA ) had positive effects and Capital (LC), Debt (LB ) had a negative effect. Other factors did not produce significant results.


The invention provides a glass bottle surface spraying technology. The spraying technology is realized in a manner that a solvent is sprayed on a glass bottle to form a layer of adhesion film on the surface of the glass bottle, so that the adhesive force between the powder coating and the glass bottle is effectively increased. According to the spraying technology, food grade powder is utilized to spray the bottle body, the powder coating on the sprayed bottle body meets state requirements for hygiene and food safety in liquor industry, is environment-friendly and safe, and more advantageous compared with the production environment of oil paint; during the powder spraying process, redundant powder coating can be recovered by equipment, and the recovery rate reaches 99%, so that the cost can be reduced further; full-automatic spraying can be realized through adopting the spraying technology, labor cost can be effectively saved, operation difficulty can be reduced, and spraying quality and uniformity of the bottle body can be better guaranteed; as one-time film formation is adopted and primer is not needed, the productivity is increased by 30%-40%, and energy consumption of about 30% can be reduced.


The information era has gained a lot of traction due to the abundant digital media contents through technological broadcasting resources. Among the information providers, the social media platform has remained a popular platform for the widespread reach of digital content. Along with accessibility and reach, social media platforms are also a huge venue for spreading misinformation since the data is not curated by trusted authorities. With many malicious participants involved, artificially generated media or strategically altered content could potentially result in affecting the integrity of targeted organizations. Popular content generation tools like DeepFake have allowed perpetrators to create realistic media content by manipulating the targeted subject with a fake identity or actions. Media metadata like time and location-based information are altered to create a false perception of real events. In this work, we propose a Decentralized Electrical Network Frequency (ENF)-based Media Authentication (DEMA) system to verify the metadata information and the digital multimedia integrity. Leveraging the environmental ENF fingerprint captured by digital media recorders, altered media content is detected by exploiting the ENF consistency based on its time and location of recording along with its spatial consistency throughout the captured frames. A decentralized and hierarchical ENF map is created as a reference database for time and location verification. For digital media uploaded to a broadcasting service, the proposed DEMA system correlates the underlying ENF fingerprint with the stored ENF map to authenticate the media metadata. With the media metadata intact, the embedded ENF in the recording is compared with a reference ENF based on the time of recording, and a correlation-based metric is used to evaluate the media authenticity. In case of missing metadata, the frames are divided spatially to compare the ENF consistency throughout the recording.


With the rapid development of the city,the suburb scenic areas has been threatened by the urbanization.But in recent years,the government has strengthened the protection for the landscape resources,so the contradiction between protection of scenic areas and development of its backing city is becoming more and more obvious.Co-ordination between them is an imminent thing.Based on the basic features and existing problems of the suburb areas and taking the scenic areas of Zhongshan as an example,some ideas and suggestion are brought forward for the co-ordination between the development of the backing city and the protection of the landscape resources so as to achieve the organic integration of the town construction and surrounding of scenic areas.


In the Altai permafrost exists which is confined to burial mounds dated at 2000-2500 years old. This indicates that, under favourable conditions, permafrost may occur at elevations 1000m lower than is commonly believed at present.

Dans l'Altai, les seuls ǐlots connus de pergelisol sont des buttes cryogenes vieilles de 2000 a 2500 ans. Elles indiquent que, sous des conditions favorables, un pergelisol peut exister a des altitudes de 1000m inferieures aux limites connues aujourd'hui.


On 25 March 2014, the Rada pre vysielanie a
retransmisiu (Council for Broadcasting and Retransmission of
the Slovak Republic) delivered a decision that formally terminated
the legal proceedings taken against the public service broadcaster
(PSB). The strictly formal decision (with no reasoning since no
sanction was imposed) was however adopted based on the judgment of
the Supreme Court (�Court�) of 26 September 2013 which
overruled the original decision of the Council in the given
case.


Having two intake valves and two exhaust valves 12, 11 of the multicylinder internal combustion engine, wherein the intake valve 12 and exhaust valve 11 are arranged in the longitudinal direction on both sides of an internal combustion engine, and the intake valve 12 and an exhaust valve by the camshaft 11 through an intake valve 4 and exhaust valve rocker hip drive arm 5, is a feature of the present invention, not only the intake valve and the exhaust valve rocker arm 4 hip roll 5 are as forked arm configuration, each of the rocker arm fork 4, 12 and 11 respectively drive the two valves with the same name on each cylinder 13, and the intake valve and the exhaust valve rocker arm 4 4a 5 of the hip axis, staggered. 5A, most good is above the other.


A within-subjects experimental design was used to study the impacts that 3 popular and successful techniques used in US studies had on the performance of workers in the largest textile factory in Russia. The results demonstrate both the potential benefits and problems of transporting US-based human resource management theories and techniques to other cultures. The finding confirmed 2 hyphotheses, which predict that extrinsic rewards and behavioral management interventions will have a positive impact on the performance of Russian textile workers. However, 2 other hypotheses, which predict that a participative intervention will not result in improved performance, was also confirmed. The participative intervention seemed to have a counterproductive effect on the Russian workers' performance. The failure of the participative approach, however, does not mean that this approach will not work across cultures. Historical and cultural values and norms should be recognized and overcome for such a technique to work effectively.


Over the last decade, low-permeability tight shale formations in the Western Canada Sedimentary Basin (WCSB) have been extensively developed using hydraulic fracturing (HF) techniques for oil- and gas exploration. In the meantime, an increasing number of M3+ earthquakes (e.g., ML 4.5 11/30/2018 near Dawson Creek, and an Mw 4.6 08/17/2016 near Ft. St. John) has been associated with HF operations. By increasing the seismicity in areas of low historical seismicity, the relationship between operational parameters and the rate of fault activation needs to be fully understood to avoid economic losses due to operation shutdowns or damages caused by ground shaking.

As earthquakes follow a well-known power-law magnitude-frequency relation, standard earthquake catalogs are typically dominated by microearthquakes in quantity. However, they usually still miss a large number of earthquakes due to insufficient station coverage and/or limited duration of observation. The latter could also lead to an inadequate time window for detecting larger earthquakes, which results in uncertainties of the power-law relation parameters for a particular area.

Here, we enhance a local seismic catalog derived from a dense seismic network in the Kiskatinaw (Montney Formation) area in British Columbia, Canada, using a multi-station matched filter technique. The existing automated STA/LTA catalog > 8000 earthquakes contains earthquakes from July 2017 - July 2020 with manually revised phase arrivals from up to 25 broad-band stations, ranging between ML -0.6 to 4.5. Using all the ~8000 events from the initial catalog as templates, we detected > 40,000 additional earthquakes, lowering the magnitude of completeness Mc from ~1.3 to ~0.2. We observe a b-value of approximately 1, and the majority of events occurred between 1.0 - 3.0 km depth, where injection depths range from 1.5 - 2.5 km.

In addition to the previously observed clustering of earthquakes around specific HF wells, we also observe ~8000 earthquakes with no apparent spatial (up to 5 km) or temporal (within two weeks of the reported HF stimulation) connection to HF operations. We estimate the contribution of the uncorrelated events to background seismicity rates. Furthermore, we detect earthquakes with templates related to HF operations, with spatial, but lacking temporal correlation to HF stimulation. Spatially correlated earthquakes with a no temporal correlation could highlight either areas with delayed induced seismicity (if following well stimulation) or areas with previous background seismicity (if preceding it). We will also show the correlation between background seismicity rates and cumulative injection rates and volumes of all wells within the study area.


The microstructures of NiAl-Fe (Ni, 50.3at % Al, 0.28 at% Fe) polycrystals tested in HCF (high cycle fatigue) below and above the DBTT (ductile to brittle transition temperature) viz., 673 K, 823 K, 873 K and 928 K at different stress amplitudes were observed by transmission electron microscopy. The microstructure consisted of low energy dislocation networks and dislocation cells. The fundamental features of the dislocation structures are described. Misorientation angles between cells were measured from Kikuchi patterns obtained from cells through microdiffraction. The misorientations across the cell walls were found to increase with increase in the stress amplitude to which the material was subjected during cycling. The mechanisms for the formation and evolution of these structures are discussed on the basis of existing theoretical models. The implications of these substructures on the mechanical properties are also discussed.


This study was carried out to investigate the effec ts of ethylacetate and n-butanol fractions of Indig ofera pulchra on lipid peroxidation and antioxidant enzymes on normo glycaemic and alloxan induced diabetic rats. Diabe tes was induced by a single intraperitoneal injection of al loxan dissolved in 0.9%v/v cold normal saline solut i n at a dose of 150 mg/kg body weight, after which the rats were ra ndomly divided into four groups for diabetic study and four groups for the normoglyceamic study . After 14 day s of treatment, the animal were anaesthetized and s crificed to obtained blood by cardiac puncture. Serum was colle ted and assayed for lipid peroxidation, superoxide dismutase and Gluththione peroxide (MDA, SOD, GPx) As regards to the normoglyceamic groups there was no signific ant change in the levels of malonaldehyde, supraoxide d smutase and gluthathione peroxidise when compared with untreated control group. Although in the diabetic treated groups with the ethyl acetate and n-butanol fractions there was a significant decrease in the level s of malonaldehyde when compared with the control diabet c untreated group. In relations to the antioxidant biomarkers ( SOD and GPx) there were no significant change, but there was an increase in the levels when compared with the co ntrol. The preliminary phytochemical screening of the two fractions Indigofera pulchra fractions revealed the presence of alkaloids, flavonoids, and saponins. T he LD50 was 775mg/kg and 2,154 mg/kg for Ethylacetate and n-But anol fractions respectively.


The high reported rates of work related musculoskeletal disorders (WMSD) and accidents among butchers and deboners in Sweden have resulted in several initiatives to reduce these. In this study, eig ...


. In modern conditions, one of the priority directions of potato growing is the selection of new highly produc-tive varieties, resistant to the action of abiotic and biotic factors. When potatoes are cultivated, the optimization of mineral nutrition and the depth of planting of seed tubers is an important factor for obtaining sustainable yields. The experiments were laid on gray forest medium loamy granulometric composition of the soil of


Modern computing networks that enable distributed computing are comprised of a wide range of heterogeneous devices with different levels of resources, which are interconnected by different networking technologies and communication protocols. This integration, together with the state of the art technologies, has brought into play new uncertainties, associated with physical world and the cyber space. In heterogeneous networked control systems environments, awareness and resilience are two important properties that these systems should bear and comply with. In this work the problem of resilience enhancement in heterogeneous networked control systems is addressed based on a distributed middleware, which is propped up on a hierarchical multi-agent framework, where each of the constituent agents is devoted to a specific task. The proposed architecture takes into account physical and cyber vulnerabilities and ensures state and context awareness, and a minimum level of acceptable operational performance, in response to physical and cyber disturbances. Experiments on a IPv6-based test-bed proved the relevance and benefits offered by the proposed architecture.


Perioperative anxiety can have a profound and lasting effect on children and their parents, with up to 70 percent of children undergoing outpatient surgery experiencing significant physiologic and/or psychological manifestations of anxiety throughout the ambulatory surgical process. The physical healthcare environment itself can contribute to these feelings, substantially impacting the level of anxiety experienced by both the child and their parent.


Object To determine the concentration and pharmacokinetic changes of puerarin in retinal tissue of rabbits by ip administration. Methods Forty-four rabbits were randomly divided into 11 groups. Puerarin (80 mg/kg) in addition of 5% glucose solution was given by ip administration to each rabbit in every groups. After administration, the retinal tissue was collected at different time points such as 0 h pre-administration and 0.5, 1, 2, 3, 4, 6, 8, 12, 16, and 24 h post-administration and the concentration of puerarin was detected by RP-HPLC. The pharmacokinetic parameter was fitted by 3P87 software. Results The pharmacokinetics of puerarin in the retinal tissue was subjected to the two-compartment open model. The pharmacokinetic parameters were separately as following: C max=1.08 μg/mg, t max=1.52 h,t 1/2 α=1.02 h, t 1/2 β=7.37 h, CL=2.67 g/h, AUC=6.89 μg/(h·mg). The practical data of the concentration of puerarin in retinal tissue was (0.06±0.02) μg/mg at 30 min and maximum concentration was (0.21±0.05) μg/mg at 2 h, respectively. Then the concentration of puerarin in retinal tissue was gradually decreased to the lower level (0.02±0.00 μg/mg) at 8 h. Conclusion The method of RP-HPLC is particular, accurate, and sensitive. The puerarin by ip administration can penetrate the blood-retina barriers and enter the retinal tissue.


ABSTRACT Pornography use is prevalent, even among partnered individuals. Although pornography use motivations represent key predictors of sexual behaviors, prior studies only assessed the associations between pornography use frequency and sexual wellbeing, with mixed results. This cross-sectional dyadic study examined the associations between partners' individual and partnered pornography use frequency, motivations, and sexual wellbeing. Self-report data from 265 couples (Mage_men = 31.49 years, SD = 8.26; Mage_women = 29.36 years, SD = 6.74) were analyzed using an actor-partner interdependence model. Men's greater emotional avoidance motivation was related to their own lower sexual function (β = −.24, p = .004) and greater sexual distress (β = .19, p = .012), while their higher sexual curiosity motivation was related to higher partnered sexual frequency (β = .15, p = .031), their own greater sexual satisfaction (β = .13, p = .022), sexual function (β = .16, p = .009), and lower sexual distress (β = −.13, p = .043). Women's higher partnered pornography use frequency was associated with their own greater sexual function (β = .15, p = .034) and lower sexual distress (β = −.14, p = .012). Additionally, women's higher individual pornography use frequency (β = .33, p < .001) and lower sexual pleasure motivation (β = −.35, p = .002) were associated with higher partnered sexual frequency. No partner effects were observed. Findings highlight that women's pornography use frequency and each partner's motivations might play crucial roles in couples' sexual wellbeing.


ranged from 145.17 to 59.94% in front-crawl, from 192.39 to 85.57% in dolphin, from 298.03 to 124.50% in breaststroke, and from 162.87 to 83.61% in back-stroke In the male sweet variations in F~~~.~,~/F~~.~,~ ranged from 162.24 to 62.39% in front-crawl, from 191.70 to 70.38% in dolphin, from 295.57 to 102.83% in breaststroke, and from 198.82 to 7448% in back-stroke. The main reason for such variations is found in the individual features of swimming technique and can be quantitatively estimated with the hydrodynamic force coefficient, which thus provides an adequate index of technique.