The article deals with the typological parallels between Kate Chopin's literary-artistic system and philosophical doctrine of transcendentalism. As well as the majority of the writers of that time Kate Chopin could not avoid the influence of the ideas determining the peculiarities of cultural atmosphere in America, Ralf Waldo Emerson's ideas in particular. Emerson's philosophical and aesthetic conception proclaimed individual freedom the highest value, pointed out the intuitive nature of creative work. American transcendentalism encouraged to depict even mundane life events, empowered the art with a special role in the discovery of the world. These provisions were especially close to Kate Chopin and were rather peculiarly embodied in her works. Thus, Kate Chopin depicted mundane events from American life in all their diversity. In her works art is a way to penetrate into the deepest core of existence. The cross-cutting theme of Kate Chopin's writing was her heroines' understanding of their own significance, the necessity of freedom and self-realisation and that coincides greatly with Emerson's "self-reliance" doctrine. Nevertheless, transcendentalism ideas being a part of cultural code of the time combined in Kate Chopin's works with her individual worldview and that reflected in special ironic implication of her prose.


The Royal residence of Carditello, known as " Royal Casino", is considered one of the most beautiful and architecturally refined Reali Delizie "ville de delizie" made by King Ferdinand of the house of Bourbon. Commissioned in the spring of 1784 for the purpose of providing necessary rural housing for the King's animals, processing related products, and providing housing for staff, Carditello was much loved by the King. In 1787, work began on building up the small "Casino" (or "country house") designed by Francesco Collecini. Fully furnished, the royal residence made a display of beautiful curtains, a rich art gallery and a multitude of books, as documented by the first inventory of the site, prepared immediately after its completion in 1792. In the official documents called Amministrazione di Carditello e Calvi - Conti e Cautele preserved in the Historical Archives of the Royal Palace of Caserta, there are various records that attest to the payments for work done at the apartment of the king in "Cardito" by Fedele Fischetti, and thanks to them we have been able to reconstruct the existence of works by the Neapolitan Fischetti in the Gallery of Carditello. The Gallery of Carditello, which was the main hall of the building, was commissioned and intended to be the more opulent and richer space in the apartment where Fedele Fischetti painted the frescos on the vault, drew the preparatory models of tapestries and perhaps prepared the designs for the magnificent and expensive furniture of French production.


A technique is described for the preparation of fine particle rare earth orthoferrites in a wide range of compositions. These compositions include those containing a single rare earth, multiple rare earths, single and multiple rare earths with excess iron or excess rare earth, and these same combinations with partial substitution of iron with cobalt. The technique is relatively simple and involves a precipitation and decomposition of the precipitate in a muffle furnace.


This paper will focus on Bouc-Wen hysteresis model to study the time-scale similarity of the hysteresis. Considering different hysteresis characteristics of Bouc-Wen model, this paper studies the time-scale similarity between the output curves of different hysteresis characteristics under the excitation of the triangular waves with different frequencies, and the Euclidean distance function is used to measure the curve similarity. The time-scale similarity proposed in this paper will contribute to establishing a dynamic similarity model, which is without complex operation and don't need a lot of storage space.


Comments are given on the conservation status of Victoria's butterflies, summarising and bringing up-to-date the information previously available in published documents.


An experiment was conducted during rabi season 1997–98 to evaluate net-radiation using-multi band remote sensing and ground base meteorological data. The net radiation (Rn) were measured with net radiometer 1 meter above wheat crop. The values of net radiation ranged from 458 to 691 w/m2 during all the growth stages. The net radiation was also computed using remote sensing and meteorological data. A regression equation was developed between actually measured (Rn) and remotely sensed (Rn) net radiation values, which is expressed as: This equation can be used to estimate net radiation using remote sensing and meteorological data into actual values.


Bath before his death in January . James's critical determination to recover Errington's reputation from the damage done to him by both contemporaries and historians is evident throughout this book. James is particularly thorough in his analysis of the breakdown of Wiseman and Errington's relationship, demonstrating how two shining stars of the post-emancipation English Catholic Church, who shared a similar education at the English College in Rome but whose personalities were incompatible, could find it almost impossible to work together. Errington was the archetypal administrator; well-organised, financially astute, thorough in detail and not afraid to be critical of others if he observed a point of canon law being contravened. Conversely, Wiseman did not take kindly to criticism and expected unquestioned loyalty from his bishops. Indeed, by the time of the cardinal's death in , their relationship had deteriorated to such an extent that Errington could not even bring himself to attend his former school friend's funeral. This had a profound effect on Errington and helps to explain why he was suspicious of the hierarchy's offer of the archbishopric of Glasgow. James is particularly good on the smaller details of Errington's life – something the archbishop himself would no doubt have appreciated. Away from the pressures of the episcopate, Errington spent the little free time he allowed himself in pursuing his own interests, notably in botany when he could often be found studying the flowers in the hedgerows alongside the navvies building the nation's bridges and railways. His strong sense of duty and responsibility was a lifelong characteristic. It is somehow fitting that, when told that he only had a few hours left to live, the bedridden Errington spent most of this time marking the essays of his Prior Park students. Criticisms are minor. There is a useful bibliography of secondary sources at the end of the volume but no list of primary sources, although these are referenced in footnotes. The introduction, setting out the context of Catholic history in England from the Reformation to the nineteenth-century, is perhaps a little unnecessary. In general, however, this is an excellent, highly readable book deserving of a larger and broader audience than its price tag will probably permit. James's research should go a long way towards achieving his aim of redeeming Errington's reputation for posterity.


Single‐ and multiple‐energy Be, S, Si, and Ne ion implantations were performed at room temperature in InSb grown on semi‐insulating GaAs substrates. The implanted material was subjected to both isochronal and isothermal annealing schemes. The as‐implanted and annealed material was characterized by Hall, secondary ion mass spectrometry, and x‐ray rocking curve measurements. The as‐implanted material is highly n‐type for all implant species used in this study. A maximum p‐type activation of 90% and n‐type activation of 16% was achieved for Be and S implants, respectively. Be activation depends on the thickness of the InSb layer. No in‐diffusion of Be and S was observed even after 500 °C anneal. The Si implant has an amphoteric doping behavior.


We show that the Schur multiplier of Sp(2g,Z/DZ) is Z/2Z, when D is divisible by 4. We give several proofs of this statement, a first one using Deligne's non-residual finiteness theorem and recent results of Putman, a second one using K-theory arguments based on the work of Barge and Lannes and a third one based on the Weil representations of symplectic groups arising in abelian Chern-Simons theory. We can also retrieve this way Deligne's non-residual finiteness of the universal central extension ^ Sp(2g,Z) and a sharp result since ^ Sp(2g,Z) surjects on the non-trivial central extension of Sp(2g,Z/DZ) by Z/2Z, when g � 3. We prove then that the essential second homology of finite quotients of symplectic groups over a Dedekind domain of arithmetic type are torsion groups of uniformly bounded size. In contrast, quantum representations produce for every prime p, finite quotients of the mapping class group of genus g � 3 whose essential second homology has p-torsion. We further derive that all central extensions of the mapping class group are residually finite and deduce that mapping class groups have Serre's property A2 for trivial modules, contrary to symplectic groups. Eventually we compute the module of coinvariants H2(sp2g(2))Sp(2g,Z/2kZ) = Z/2Z.


Tactile-thermal application for treating dysphagia has a tumultous history. This paper reviews the method's history and selected data, outlines the theoretical underpinnings of sensory stimulation,...


Within the context of food safety, risk analysis is used to quantify the risks caused by food-borne hazards to human health, and to identify, assess and implement appropriate measures of intervention to control the risks. According to the Regulation EC No.178/2002 of the European Parliament (http://www.fsai.ie/legislation/food/eu_ docs/Labelling/Cor_Reg1924_2006.pdf) , risk analysis should be seen as a structured decision-making system comprised of three highly interrelated components: risk management, risk assessment and risk communication. The role of "risk managers" is generally played by governmental food safety officials, who have the ultimate responsibility for selecting and implementing the most efficient food safety control measures. Thus, risk managers need to fully understand the logic and the outcome of a risk assessment study in order to make appropriate risk management decisions.


Convective weather is known to reduce airspace capacity, but the extent of the impact is not well understood. Understanding how weather impacts terminal area capacity is essential for quantifying the uncertainty in weather forecast, determining how accurately the weather needs to be forecast, for developing an optimal mitigation strategy. Prior research has focused on the overlap between convective weather cells and air routes, but has not sufficiently analyzed the differences that arise due to factors such as aircraft types and pilot behavior. This paper examines the interactions between convective weather and aircraft trajectories in the arrival airspace surrounding Chicago O'Hare International Airport. Case studies based on operational data are used to determine potentially relevant operational factors, and a predictive model is built using these factors to forecast if a flight will pass through hazardous weather. The results of the analysis suggest that these operational factors are secondary compared to the weather itself in determining whether a pilot will deviate from or penetrate hazardous weather.


This article explores the relationship between surveillance capitalism, big data, and the emergence of a new type of datafied citizenship by looking at two different, yet interconnected, dimensions. In the first place, it considers how under surveillance capitalism individuals are being profiled simultaneously as consumer and citizen subjects by a complex political economic infrastructure that brings private and public entities together. In the second place, it argues that surveillance capitalism depends on the systematic coercion of digital participation, which forces citizens to comply with data technologies and give up their personal data. If we want to understand the extent of these transformation, the article argues, we need to look at children. Children have traditionally been excluded from debates about citizenship because they have often been understood as not-yet citizens or future citizens. Yet, in the study of the relationship between data and citizenship, children today are the key. They are the very first generation of citizens who are datafied from before they are born and are coerced into digitally participating to society through the data traces produced, collected, and processed by others without their consent or control. Drawing on the findings of the Child | Data | Citizen project, an ethnographically informed research project on big data and family life in the UK and US, this article will highlight some of the democratic challenges that emerge when we think about data, surveillance capitalism, and citizenship in everyday life.


Various business analytics depend on collection and analysis of large volumes of data. Data from multiple sources may need to be integrated and examined to draw fruitful results. Lack of a global unique identifier and other data inconsistencies pose challenges in linking such data. Existing record linkage approaches set certain prerequisites in form of either training data or known match status of databases under consideration. These approaches rely particularly on the problem datasets and are practically infeasible for large volumes of disparate real-world data. The proposed signature-based clustering approach generates multiple signatures of each record and clusters similar records together using affinity propagation clustering technique. Each set of clustered records is then represented by its representative feature. High performance of the proposed algorithm on various real-world and synthetic datasets indicates its efficiency over existing approaches. The proposed system generates matching results with an average 92% accuracy. Representation of each set of similar records by a single representative feature greatly reduces the number of overall comparisons and memory requirements of the matching process, thereby improving the matching quality.


The percentage of women pulling up chairside in the operatory is increasing. And studies show that women in dentistry experience a higher frequency and severity of pain than their male counterparts, with the thumbs, hands, hips, neck, and shoulder being particularly problematic.


Data collected at the end of the program or following the close of the program. This design is often used when resources are very limited or when participants were not available at the start of the program for a pretest. A limitation of this design is that it does not have a reference point for comparison such as a pretest or comparison group. Given this, it is difficult to determine the magnitude of the outcome or where the outcomes are due to the program or due to other causes.


Objective— Inflammation is associated with the formation of aortic aneurysm. This study investigates the role of Cys-X-Cys chemokine receptor (CXCR)3 and its ligands, in the pathogenesis of arterial aneurysms. Methods— Plasma samples from patients with or without a diagnosis of thoracic aortic aneurysms were analyzed by ELISA for the Th1 cytokine interferon (IFN)- γ as well as the IFN- γ inducible CXCR3 ligands, IP-10, I-TAC, and Mig. Patient charts were reviewed for demographics, initial aortic diameter, and growth rates. Aneurysm diameter and growth rates were correlated with plasma cytokine and chemokine levels using linear regression analysis. We used an animal model of aneurysm formation, where calcium chloride is applied topically to carotid arteries of wild type and CXCR3 −/− mice. After 10 weeks, the arteries were harvested and analyzed by histology and immunohistochemistry. Results— Patients with thoracic aortic aneurysms had significant elevations in circulating IFN- γ , IP-10, I-TAC, and Mig compared to referent patients (p<0.001). Cytokine and chemokine plasma levels did not correlate with aneurysm size or growth rates. CXCR3 −/− mice were protected from aneurysm formation and showed decreased vascular infiltration by CD45 + leukocytes. Conclusions— Elevated plasma levels of IFN- γ and CXCR3-binding chemokines are present in patients with thoracic aortic aneurysms. The CXCR3 receptor is necessary for vascular inflammation and the formation of arterial aneurysms in mice. Analyses of clinical specimens and experimental models of the role of inflammation in the of aneurysmal where medial degeneration and vascular cell death in is associated with segments of the aorta different embryological ascending aorta and arch are of neural crest correspond to the embryological dorsal aorta. Our animal model of aneurysm formation used the carotid may have different results than in the aorta. similar results have been reported in the aorta and carotid arteries and carotid of embryologically similar derivation as thoracic aorta but not aorta. Other a IFN- in chloride-induced aneurysms the


Four naphthalene-degrading bacteria (Pseudomonas sp. strains O1, Wl, Asl, and Gl) were isolated from pollutant-contaminated sites. Examination of their substrate utilization and analyses of key naphthalene-catabolic regulatory genes revealed that the pathway and regulation of naphthalene-degradation in all four strains resemble those of NAH7 from P. putida G7. Superoxide anion production, superoxide dismutase activity, and catalase activity during their growth on naphthalene-amended medium increased significantly, compared with those with glucose-amended medium. Addition of ascorbate, an antioxidant, or ferrous iron (Fe 2+ ) increased the growth rates of all tested microorganisms on naphthalene. Northern blot and HPLC analyses showed that both nahA gene expression and naphthalene degradation increased under those conditions. Our data suggest that naphthalene degradation can impose severe oxidative stress, and defenses against oxidative stress would play an important role in the metabolism of naphthalene.


Red phosphors of Gd1-xAl3(BO3)4:Eux3+ were synthesized by using the solid-state reaction method. The phasestructure and morphology of the phosphors were measured using X-ray diffraction (XRD) and field emission-scanning electronmicroscopy (FE-SEM), respectively. The optical properties of GdAl3(BO3)4:Eu3+ phosphors with concentrations of Eu3+ ions of0, 0.05, 0.10, 0.15, and 0.20mol were investigated at room temperature. The crystals were hexagonal with a rhombohedrallattice. The excitation spectra of all the phosphors, irrespective of the Eu3+ concentrations, were composed of a broad bandcentered at 265nm and a narrow band having peak at 274nm. As for the emission spectra, the peak wavelength was 613nmunder a 274nm ultraviolet excitation. The intensity ratio of the red emission transition (5D0→7F2) to orange (5D0→7F1) showsthat the Eu3+ ions occupy sites of no inversion symmetry in the host. In conclusion, the optimum doping concentration of Eu3+ions for preparing GdAl3(BO3)4:Eu3+ phosphors was found to be 0.15mol.


Domestic sugar production has been finished in 201213 crushing season, producing 13. 068 4 million tons sugar,up 13. 47% from the crushing season earlier. In 201213 crushing season,the successive surplus of global sugar and recession of macro-economics made international sugar price below 37. 48 cents per kilogram. With weak international sugar price and great domestic sugar supply,domestic sugar price was under a lot of pressure to go down. To protect the interests of sugar farmers and mills,the Ministry of Commerce has successively purchased three times a total of 1. 8 million tons of sugar reserves,with base price6 100 RMB per ton,but the effect of reserving policy to support domestic sugar price was not obvious,spot price fell below 5 500 RMB per ton and futures price below 5 000 RMB per ton. High prices in 2010 and 2011 have stimulated sugar planting areas to expand, according to data from China Sugar Association, national sugar planting area was 1. 902 32 million hectare in 2012,up 5. 05% against 2011,and 201213 crushing season was the second production increase crushing season. Looking forward to 201314 crushing season,due to production increase in India,Thailand and Russia,world sugar market will be the third oversupply crushing season,in the future international sugar prices will be difficult to gain a sharp rebound; though domestic sugar production is in the increase cycle and gap between supply and demand has narrowed, spreads between home and abroad will continue stimulating international sugar imports,domestic sugar in the new crushing season will still face the pressure of oversupply. As at present imported sugar is the main reason for the surplus of domestic sugar market,domestic sugar price in 201314 crushing season will mostly depend on global sugar production.


Biological, physical and mechanical properties of silver-doped layers of titanium alloy Ti6Al4V and 316L steel prepared by pulsed laser deposition were studied. Metallic silver-doped coatings could be a new route for antibacterial protection in medicine. Thin films of silver and silver-doped materials were synthesized using KrF excimer laser deposition. The materials were ablated from two targets, which were composed either from titanium alloy with silver segments or from steel with silver segments. The concentration of silver ranged from 1.54 at% to 4.32 at% for steel and from 3.04 at% to 13.05 at% for titanium alloy. The layer properties such as silver content, structure, adhesion, surface wettability, and antibacterial efficacy (evaluated by Escherichia coli and Bacillus subtilis bacteria) were measured. Film adhesion was studied using scratch test. The antibacterial efficacy changed with silver doping up to 99.9 %. Our investigation was focused on minimum Ag concentration needed to reach high antibacterial efficiency, high film adhesion, and hardness.


Epitope mapping provides essential information for differentiating monoclonal antibodies (MAbs) that bind to proteins targeted by many competing drugs. In cancer immunotherapy, for instance, numerous approved or investigational MAbs target the immune checkpoint protein PD-1. Recent high-profile patent law cases have centered on epitope data, highlighting the importance of distinguishing MAb binding sites at amino-acid resolution. Additionally, epitope data can be used to distinguish the mechanisms by which MAbs exert their therapeutic effects, uncovering important differences between competing drugs. To achieve rapid and comprehensive conformational epitope mapping at the amino-acid level, we developed the Shotgun Mutagenesis Epitope Mapping platform. Every residue in a target protein is individually mutated by alanine scanning mutagenesis, expressed in human cells, and assayed by flow cytometry to determine the critical epitope residues. Data from our platform have been used to differentiate MAbs in terms of their binding residues and therapeutic mechanisms of action. We have used our platform to differentiate the unique binding residues and, in some cases, the mechanisms of action of novel MAbs on the crowded surfaces of cancer targets, such as HER-2, from those of benchmark MAbs. Citation Format: Sharon Willis. High-resolution epitope mapping differentiates monoclonal antibodies in the crowded cancer immunotherapy space [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 1220.


Blogs are certainly at the forefront of the Web 2.0 movement. Blogging has been alternativelycategorized as both "the next big thing" (Gallo, 2004) and an "Internet Wasteland" (Anonymous, 2003).In a nutshell, a blog can be differentiated from a website in that it is an easier to create and update webvehicle, usually simply by typing into a preprogrammed interface. From a definitional perspective, ablog refers to an online journal that can be updated regularly, with entries typically displayed inchronological order. While blogs now encompass not only text, but video and audio as well, it isgenerally accepted that if the individual posts/items/articles that cannot be linked to separately via apermalink (rather then just linking to the whole site), then the site in question is not a blog. Blogs arealso commonly referred to as a weblog or web log, with blog actually being the short form of theseterms. Blog is also a verb, meaning to write an article on such an online journal.


Kaposi's sarcoma (KS) is a complex neoplasm of cells of endothelial and fibroblast origin, whose proliferation is maintained by the viral product Tat, cytokines, and maybe environmental factors. It was among the first noted clinical manifestations of AIDS and remains the most common malignancy observed in patients infected with HIV, yet an optimal treatment strategy remains to be identified. The authors discuss current options and future directions for the systemic treatment of KS. They do not, however, address local forms of treatment. It is concluded that angiogenesis inhibitors may provide a novel therapeutic approach in the near future, while single agent cytotoxic chemotherapy and combination chemotherapy may induce remissions in the majority of patients along with relief from the morbidity of edema, disfigurement, and pain. Interferon is effective mainly in patients who are not severely immunocompromised. Finally, systemic therapy for AIDS-associated KS must be integrated with antiretroviral therapy, prophylaxis for opportunistic infections, and appropriate hematological support. Sections explore the etiology and pathogenesis of KS, rationale for systemic treatment, single-agent chemotherapy, combination chemotherapy, chemotherapy and antiretroviral agents, interferon, interferon and antiretroviral therapy, interferon and chemotherapy, other biological agents, angiostatic compounds, and anti-Tat therapy. Innovative treatment approaches to KS may ultimately prove applicable to many other neoplastic disorders.


Using the grey relevancy analyzing method of grey system theory, optimization and selection on several feasible ventilation system alteration schemes of Pingdingshan Coal Mine No 6 is made, and finally the optimal ventilation scheme is gotten, which some air supply in Wu 2 mining area are borne by Ding 2 airshaft, and the fans angles of rooting in of blades will be increased to +5°. It not only guides practical production, but also provides a new way and scientific theory basis for future scheme optimization work and muti object decision making problems.


of error. The looming phenomenon was known to the ancients, and had certainly not been forgotten: Jefferson discussed it in his 'Notes on the State of Virginia' (1781– 82), Scoresby had carefully documented similar unusual refraction phenomena off Greenland in the 1820s, and theoretical explanations already existed. So what is the purpose of this parable? Is it to remind us that we can all make mistakes? Or that it is difficult to get large projects funded? Or is its purpose to establish the entry of the United States into the field of polar exploration? The story is revisited briefly in chapter 3, where a couple of pages draw parallels between the fact that credit for discovery of the Antarctic ozone hole went to the British Antarctic Survey with their ground-based data rather than to NASA with their TOMS data, and the fact that Captain Wilkes received less credit than he deserved for midnineteenth century Antarctic discoveries. I must admit that I could not really see the point that the authors were trying to make here, or why NASA would need to be defended against a charge of sitting on their data rather than publishing it, when the data were derived from a new and only partially validated technique. But setting aside the question of relevance, it is an interesting digression. (W.G. Rees, Scott Polar Research Institute, University of Cambridge, Lensfield Road, Cambridge CB2 1ER.)


Two compactifications of the space of holomorphic maps of fixed degree from a compact Riemann surface to a Grassmannian are studied. It is shown that the Uhlenbeck compactification has the structure of a projective variety and is dominated by the algebraic compactification coming from the Grothendieck Quot Scheme. The latter may be embedded into the moduli space of solutions to a generalized version of the vortex equations studied by Bradlow. This gives an effective way of computing certain intersection numbers (known as "Gromov invariants") on the space of holomorphic maps into Grassmannians. We carry out these computations in the case where the Riemann surface has genus one. Department of Mathematics, University of Utah, Salt Lake City, Utah 84112 E-mail address: email@example.com Department of Mathematics, Brown University, Providence, Rhode Island 02912 E-mail address: email@example.com Department of Mathematics, University of California, Irvine, California 92717 E-mail address: firstname.lastname@example.com License or copyright restrictions may apply to redistribution; see http://www.ams.org/journal-terms-of-use


The 'rational expectations hypothesis (REH)' assumes that investors' subjective probability measures coincide with their objective probability measures and all new and relevant information is instantaneously absorbed into these objective distribution measure or prices. A related idea is the efficient market hypothesis which states that the prices of securities as observed reflect all publicly available information. The observed randomness of asset returns re-affirms this line of argument. However, the empirical nonnormality (or fat-tails) of the return distributions continues to be an unexplained anomaly. This paper is based on the rational expectations hypothesis but allows the objective probability measures to be modified to form subjective expectations. Investors remain rational but they revise their original expectations prior to trading based on their buy-sell decisions i.e. they attempt to maximize their expected utilities by adopting decision-biased extreme-valued posterior subjective probabilities based on their prior objective probability measures. A hypothesis called the 'extremal expectations hypothesis (EEH)' is proposed using extreme-valued theory concepts to support the empirical findings.


Agreed clinical protocols are probably the best way of selecting suitable investigations for the diagnosis or exclusion of a specific clinical condition.' Problems arise when the clinical condition is thought of as a (morphological) diagnosis (by physicians) and not as a complex pathophysiological process (recognized by laboratory scientists). Furthermore, clinical chemists and physicians differ significantly when judging the utility of a particular quantity.* Processes should be evaluated more frequently. A typical example of this is osteoporosis, a disorder that may be the result of several pathological processes. Laboratory tests that might be requested include osteocalcin, bone alkaline phosphatase, propeptides or telopeptides of type I collagen, urinary deoxypyridinoline and others. Some results (of catalytic activity or substance concentrations) may fall within the reference interval, while others will be above or below this interval. There are many variations in this data set which can be consistent with the diagnosis of osteoporosis, but none which prove or exclude it. The presence of pathophysiological processes, which are reflected by the above mentioned quantities, do not necessarily confirm the diagnosis as a morphological disease.


What was your favourite book as a child? Remember the joy of reading it over and over again until the pages were worn and the corners curled. Have you thought about introducing your favourite book into a mathematics classroom? Utilising books in mathematics can engage and benefit every child in your class. Building on children's wonder of literature can enhance their experience in mathematics. Building on children's wonder of mathematics can enhance their experience of literature. In this paper we present the joy and value of employing children's literature in the middle to upper primary mathematics classroom supported with engaging tasks that will have your students noticing maths in every story they read.


Abstract Background: Researchers have found that an earlier age of disorder onset and the severity of the first depressive episode are associated with recurrence in depression. Additionally, neuroticism has been shown to be an important factor in the recurrence of the disorder. Aims: This exploratory study aimed to replicate and extend previous research by examining the relationships between features of the first experienced depressive episode (age of onset, severity), the five factors of personality, and lifetime chronicity of depression. Method: Forty-three previously depressed participants completed measures of personality, current depression, hopelessness, and perfectionism. Previous depressive episodes were assessed using a semi-structured interview, and features of these episodes experienced by participants were recorded. Results: Pearson correlations showed that depression chronicity, measured in the number of weeks depressed in a lifetime, was significantly correlated with age of onset and number of symptoms experienced in the first episode. Personality measures were not significantly associated with depression chronicity. Conclusion: Earlier and more severe first episodes of depression may play an important role in the recurrence of the disorder. Future research should focus on replication and determining the causal role of these features.


With the KM3NeT experiment, which is presently under construction in the Mediterranean Sea, a new neutrino telescope will be installed to study both the neutrino properties as well as the cosmic origin of these particles. To do so, about 6000 optical modules will be installed in the abyss of the Mediterranean Sea to observe the Cherenkov radiation induced by high energy particle interactions in the deep sea. As each module of the KM3NeT telescope includes a piezo hydrophone, KM3NeT will also provide a unique matrix of underwater hydrophones. Results from the measurements show a well understood response of continuous signals, such as tones. In contrast, the response to transients signals exhibit a complex behavior with ringing and echo's. Amplitude calibration measurements show a frequency dependent response which can be corrected for. Finally a system noise floor has been determined which amounts to 45 dB Re μPa2/Hz at 30 kHz.


A First-principles research based on density functional theory is used to explore the various properties of pure and Sr-doped-KNbO3-perovskites compounds such as structural, electronic, magnetic, and optical characteristics. The Sr impact on structural, optical, electronic, and magnetic properties of Sr-doped-KNbO3 are investigated using ultra-soft pseudo-potential. The band gap of Sr-doped-KNbO3 is found to be remarkably increased from 1.50 eV to 1.83 eV after the doping of Strontium (Sr) with various percentages (0%, 12.5%, 25%, 37.5%). Under the DFT study, strontium(Sr) is appropriate material for increasing the band gap of KNbO3. Owing to the difference in ionic radii of Mo and Sr volume of crystal cells also decreased from 82.68 to 42.89 A3 after the doping of Strontium (Sr). The bandgap nature is found indirect furthermore bandgap showed that the material is a prominent semiconductor. A significant increment is obtained in the optical conductivity and also bandgap. After the doping of strontium (Sr) impurities, the energy absorption peaks are amplified. It is also observed that due to Sr substitution optical conductivity shifted toward higher energies. Sr-doped-KNbO3 has enhanced optical conductivity, energy absorption, and refractive index, making it an appropriate material for perovskite solar cell applications.


Acute respiratory disease in young children is exceedingly common and is responsible for an increase in the number of infants admitted to children's wards during the winter. Outbreaks have been reported in different parts of this country by Hubble and Osborn (1941), Garrow and Fawcett (1953), Heycock and Noble (1956) and Disney, Sandiford, Cragg and Wolff (1960). These workers and others (Morrison, Bass, Davis, Hobson, Madsen and Masters, 1957; Holland, Tanner, Pereira and Taylor, 1960b; Gardner, Stanfield, Wright, Court and Green, 1960) have indicated that knowledge of the causes is still incomplete, especially in children less than 1 year old. Most studies have been confined to the winter months and to small groups of children in localized areas. The object of this investigation was to study, epidemiologically, cases of acute respiratory illness in children admitted to hospital over a wide area during both summer and winter months. Admissions to the children's wards of 10 general hospitals, seven in the London area, one at Guildford, one at Christchurch and one at Southampton, between February 1957 and March 1958 were included (see Appendix A). During this period the outbreak of Asian influenza in 1957 occurred, followed by two outbreaks of an acute lower respiratory tract illness predominantly affecting infants. The second of these was reported in the Lancet in 1958 (Lancet, 1958). Method Paediatricians at each hospital were asked to make a monthly return of all children under 5 years of age admitted each week with acute respiratory disease. Each case was classified according to age and sex and certain diagnostic categories as set out in Appendix B. In addition, the number of children treated in oxygen tents was obtained as an indication of the severity of illness. Acute and convalescent stage specimens of blood for serological tests were obtained from a proportion of children admitted to those hospitals in the London area. Efforts were made to obtain a sample of blood from each child as soon after admission to hospital as possible and again 14 days later. Satisfactory paired samples of serum were obtained from 106 (11 *4%) of the 927 children under 5 years of age from the London area. Of these, 44 (41 5%) were less than 1 year old, whereas 409 (44-1%) of the whole group were under 1 year of age. It should be pointed out, however, that owing to the difficulty of obtaining blood samples from very young or acutely ill children, cases from which specimens of serum were tested do not represent a random sample of the whole group, and any conclusions reached from the serological results should be viewed with this in mind. In addition, paired samples were tested from 26 children aged 5-12 years, also from the London area. Each convalescent stage sample of serum was first screened at a dilution of 1/8 for complement-fixing antibodies to the following antigens: influenza viruses A, B and C; adenovirus group; para-influenza virus 1 (Sendai virus); psittacosis virus; and R. burnetii. The method employed was similar to that described by Holland, Rowson, Taylor, Allen, Ffrench-Constant and Smelt (1960a). Specimens showing more than 50% fixation were titrated in parallel with their paired acute stage samples. A fourfold or greater rise in antibody titre was regarded as evidence of concurrent infection.


The effect of trifluralin, pendimethalin, and ethalfluralin and disease caused by Rhizoctonia solani on soybean (Glycine max) was determined with field and growth chamber studies. In field studies, oats infested with R. solani placed in furrow at planting significantly reduced plant growth variables. No significant interactions were observed between herbicides and inoculum treatments. Effects of inoculum were significantly reduced with carboxin-pentachloronitrobenzene seed treatment, in growth chamber studies, steamed and nonsteamed field soil were used (...)


Ray et al. have examined the national agricultural sector impacts of the 1996 FAIR Act using a stochastic simulation model based on the Policy Analysis System (POLYSYS). The model outcomes are predictions of various economic measures, including the coefficient of variation of net returns for corn, wheat, soy-beans, and cotton. Then Knutson et al. use the results of the Ray et al. simulations to predict the distribution of net farm income over the next 10 years for several types of representative southern farms. Any attempt to measure the changes in riskiness in southern agriculture is commendable—even heroic—and I applaud these efforts, both the national modeling effort by Ray et al. and the application to southern representative farms by Knutson et al. This task has a lot in common, I think, with trying to "tease out" the temperature changes associated with the greenhouse effect. The number of factors and mechanisms at work is mind-boggling. It's tough enough to try to get a handle on what might happen to the first moment of net farm income over the next 10 years, let alone the second.


Achilles tendon rupture bilaterally secondary to predisposing factors such as steroid, fluoroquinolones, SLE, RA etc. Other factors are well-described in the literature but this is an extremely rare phenomenon in the absence of risk factors. Available reports in healthy athletes, all had history of severe trauma. We report an unusual presentation of bilateral and unilateral spontaneous rupture of Achilles tendon in healthy lifeguards without any marked trauma. Knowledge of training environment will alert the trainers, athletes and surgeons to recognise training environment at risk and take preventive measures.


Germ-line mutations in the BRCA1 and BRCA2 genes confer a predis position to breast as well as ovarian carcinoma. Except for loss of the respective wild-type alÃ-ele,somatic genetic changes needed for the pro gression of inherited ovarian tumors are unknown. A genome-wide search for such alterations was performed by comparative genomic hybridization analysis on BRCA1 and BRCA2 mutation-positive (n = 20) ovarian carcinoma specimens. Comparison with sporadic ovarian carcinomas (n = 20) revealed extensive genetic similarity between the inherited and sporadic carcinomas with the sole exception of a frequent gain of 2q24q32 in the inherited group, suggesting the presence of an oncogene at 2q24-q32 operating in the absence of BRCAI function. The overall sim ilarity of gains and losses by comparative genomic hybridization suggests a common main pathway in tumor progression of both inherited and sporadic ovarian carcinomas.


Clinostomum complanatum is a hermaphroditice parasite with an indirect life cycle. The adult worms typically live in the oral cavity and oesophagus of piscivorous birds which become infected after consuming infected fish or amphibians [7]. Metacercariae of C. complanatum are large, often yellow and encyst in a variety of sites in the body such as the oral cavity, gills, intestines, tail, muscles and eye sockets of fish or amphibians, causing the well-known "yellow grub disease". In humans, when infection occurs after the consumption of raw fish, the fluke accidentally attaches to the surface of the mucus membrane of the throat, causing a clinical syndrome called halzoun. Many cases have been described in several countries, including Japan, Korea, Thailand and India [2, 11, 15, 20] and it is considered to be an important parasitic zoonosis for public health in these countries [9]. Although no human cases have yet been reported in Iran, this could be due health practitioner's lack of knowledge about the occurrence of this parasite in local fish and/or substandard SUMMARY


And a metal wiring method for forming a semiconductor device using a fluorine the insulating film doped silica glass (FSG) of the present invention, the method comprising the step of forming a film underlying metal on the insulating film on the semiconductor substrate, the lower metal film side wall to form a metal oxide film, via contacts that comprising the steps of: forming a lower metal film and a barrier insulating film covering the metal oxide layer, forming a barrier insulating film of the silica-glass insulating fluorine-doped above and, to fluorine the through-the-doped silica glass insulating layer connected to the lower metal film a and a step with, and forming an upper metal film is electrically connected to the via-contact is formed. Metal wire, FSG dielectric film, a fluorine, a liner oxide film


This report provides an overview of business perceptions and responses to HIV/AIDS. It draws on data from three sources: the 2005-2006 Executive Opinion Survey conducted by the World Economic Forum as part of its annual Global Competitiveness Report; case studies of business action on HIV/AIDS developed by the World Economic Forums Global Health Initiative; and a survey of US business leaders commissioned by The Foundation for AIDS Research (amfAR). Nearly half of the respondents to the World Economic Forums Executive Opinion Survey expect HIV/AIDS to have impacts on their business in the next five years: The proportion of firms expecting HIV/AIDS to affect their operations in the next five years has risen from 37% to 46%. 17% now expect serious impacts compared to 14% in 2004; In countries with HIV prevalence rates above 5% nearly all respondents expect impacts on their firms operations in the next five years. (excerpt)


The relevant literature is briefly reviewed and lymphographic data obtained from 9 patients admitted to the S. L. Gonzaga Hospital are examined. In all cases, the diagnosis of sarcoidosis had been given prior to lymphography and confirmed histologically. This small series helps to show the extent of lymph node lesions in sarcoidosis and the more commonly observed adenographic features.


Purpose
Drawing on the resource-based view and contingency theory, this study aims to investigate the effects of organizational capabilities – technology capability and marketing capability – on small- and medium-sized enterprises' (SMEs') export performance and the moderating roles of contingent factors in this relationship in the context of a highly competitive export-oriented economy.

Design/methodology/approach
The research framework was tested using a three-way stepwise hierarchical multiple regression analysis with data gathered from 531 Korean international SMEs.

Findings
In addition to the direct effects of two types of organizational capabilities on export performance, the results show that both capabilities were critical when the export market was competitive, and marketing capability was more important when exporting with a brand name and targeting a developing country.

Originality/value
This study further extends the literature on SMEs' internationalization in the context of highly competitive export-driven markets and highlights the importance of strategically allocating SMEs' capabilities to reap optimal export performance by considering dynamic contingencies.


Two modelling approaches, with ALADIN-CAMx modelling system and with WRF/Chem model, have been setup for operational air quality forecast over Slovenia and the neighbouring countries. Both modelling systems started to run operationally in year 2013. ALADIN-CAMx and WRF/Chem models use data from the same anthropogenic emission databases, but differ in most other aspects. In the present contribution both modelling systems are described and the first preliminary results of model evaluation are presented. An extensive validation and verification will be performed in the coming months.


In order to enhance the working efficiency of fibre baling machinery,the original electric control system was improved.Double-speed motor was used in the improved control system.The control of different working stroke speed was realized.Both manual control and automatic control were provided at the same time.The results showed that the bailing working efficiency increased by 19.4%.The new system was very convenient and safe and the energy loss was reduced.


Colonel Whitmore tells in plain language just what lipovaccines are and within what limits their usefulness lies. His paper will dispel any misunderstanding about them in the minds of those not specialists.


The main objective of this paper is to develop and design a State Space Neural Network toolbox for a non-linear system modeling with an artificial state-space neural networks, which can be used in a model-based robust fault diagnosis and control. Such a toolbox is implemented in the MATLAB environment and it uses some of its predefined functions. It is designed in the way that any non-linear multi-input multi-output system is modeled and represented in a classical state-space form. The novelty of the proposed approach is that the final result of the identification process is the state, input and output matrices, not only the neural network parameters. The toolbox is equipped with the graphical user interface, which makes it useful for the users not familiar with a neural networks theory. This paper can be perceived as an extention of [1] on LPV systems.


The peak kW of a typical New York State office building is thought to primarily be a function of the HVAC system, often the buildings largest load, but may also be influenced by occupancy and other loads. First, a simple lumped parameter model with a minimum amount of building's physical input data, and trained with actual thermal and electrical data, is considered to approximate the thermal/electric consumption performance of the building and HVAC system on a zonal basis. Then, the lumped parameter model integrated with a dynamic human comfort model is used to develop optimized zonal thermostat setpoint schedules to minimize the cooling systems contribution to the buildings peak power load while maintaining human comfort at a desired level. A 24-hour weather and occupancy forecasts are also incorporated into the optimization algorithm. The key difference of our approach compared to previous approaches that utilize model-predictive control is that a minimal set of measurement profiles are utilized to reduce the installation cost resulting in a cost effective advanced controls solution for a large number of small and medium size office buildings. The model predictive optimization approach is implemented at multiple demonstration sites. The hardware architecture and software platform installed at one of the demonstration buildings are discussed. Finally, it is demonstrated that the proposed controller can effectively minimize peak cooling load on the HVAC equipment while achieving a satisfactory thermal comfort inside the building.


The embodiment of the invention discloses a pictorial information loading method and a related device. The pictorial information loading method and the related device are used for optimizing the overall loading speed of pictures in a grid interface. The method comprises the steps that the data information of the pictures needing to be shown in the current interfaces is acquired; the thumbnails of the pictures are downloaded from small to large according to the data volume of the thumbnails of the pictures; when downloading of the thumbnails of the pictures is completed, the complete pictures of the pictures are downloaded from small to large according to the data volume of the complete pictures of the pictures.


Effects of cutting age on short day induced flower bud differentiation and flower quality of cut chrysanthemum Seiun (Chrysanthemum morifolium Tzvel.) were studied.Flower bud differentiation,flowering process and flower quality were investigated in short day treated cuttings which were at different ages by modulating cutting and planting date.The results showed that cutting age was vital for flower bud differentiation and flower quality.The younger a cutting age was,the later the flower bud initiated. When 0 d(the day on the planting date) seedling was subjected to the short day treatment,it took 18 days for the flower bud induction and initiation.However,when the cutting age is 28 d or more,it took only 4 days for accomplishment of the above process.The younger a cutting age was,the longer the process for flower bud induction and initiation took,consequently the later the flowering date was,the poorer flower quality was.4 d is the shortest threshold for short day flower bud differentiation inducing. 28 d is the physiological mature age that is perceivable to flower bud differentiation inducing.In order to meet the standard for export of cut chrysanthemum,the cuttings should be at least 35 d old before it is subjected to flower bud differentiation inducing.


Essential components of D. Trump's tax reform and its impact on the income distribution and economic growth in U.S. are investigated. The analysis covers innovations in the system of income taxation of citizens (tax rate on income of physical persons, change in the composition of itemized and standard deductions from the taxable income, the alternative minimum income tax, limitations on the inheritance tax, and change in the mode of taxation of pass-through income).
The essence of the trickle-down economic theory is explicated, with emphasizing its central role in tax policy development in the USA, which caused occurrence of common features specific to tax reforms over the last 40 years. The considerable attention is paid in this context to the experience of tax reform introduced by R. Reagan (1986); its comparative analysis with the tax reform of D. Trump shows that with respect to income taxation both are intended to provide incentives to business and reduce tax burden on the high income population strata. However, assessment of Reagan's tax reform consequences shows that concentration of capital at the hands of businesses and high income population strata not only failed to increase employment and income, but aggravated the social and economic problems in the country, caused by revenue reduction in the American budget, the growing public debt and the enhanced social inequality in the American society. This gave experts grounds to expect an occurrence of the analogous scenario in the result of D. Trump's tax reform. The article gives a series of short-term and medium-term projected estimates of international experts for budget losses and change in the structure of the population (household) income in US.
Innovations in the system of income taxation of U.S. citizens are investigated by the results of analysis of legal norms concerning changes in the scale of tax rates and in the system of deductions from the taxable income. A number of critical comments are given about the income tax policy, based on summing up strong and weak points of the trickle-down economic theory. The most essential of them is that the policy granting more beneficial tax preferences to the well-off population strata, with their negative effects for the vertical justice of the tax burden distribution, contradicts to the ability-to-pay tax principle. Recommendations on potential testing of selected innovations on line of the taxation reform in Ukraine are given using results of the analysis.


Objective To explore the effect of Dachengqitang on intestinal endotoxemia in acute liver injured rats.Methods40 Wistar rats were randomly divided into 5 groups: normal group(group A),TAA model group(group B),treatment group of Dachengqi Decoction at low dose(group C),treatment group at moderate dose(group D),treatment group at high dose(group E).There were 8 rats in every group.The endotoxin,the levels of plasma D-lactate,TNF and ALT,TBIL were measured,intestinal content was collected for bacteriological study,liver pathology was observed.ResultsCompared with group A,the levels of endotoxin,plasma D-lactate,TNF,ALT,and TBIL in blood were significantly increased in B group(P 0.01),the rats of B group exist intestinal dysbacteriosis.Compared with B group,endotoxin,the level of plasma D-lactate,TNF,ALT,and TBIL were significantly decreased(P0.01,P0.05) in C,D,E groups.,amel intestinal dysbacteriosis were improved significantly(P 0.05).The pathological change of liver in C,D,E groups was significantly allevtiated.ConclusionDachengqitang protects rats from acute liver injury by improving intestinal dysbacteriosis and reducing the level of plasma endotoxin.


MicroRNAs(miRNAs) is a class of non-protein coding,endogenous small RNAs in animals and plants.They play important roles in regulating the expression of various mRNAs by directing mRNA degradation or repression the translation of target mRNA.The differential expression of miRNAs is not only associated with carcinogenesis,recurrence,metastasis and prognosis of gastrointestinal neoplasms,but also plays a key role in pathogenesis of many benign diseases,such as atrophic gastritis,ulcerative colitis,irritable bowel syndrome and so on.


Background: Acute patellar dislocation is a common traumatic condition of the knee seen in the active adolescent. The patterns of injury to the ligamentous and chondral surfaces following dislocation have not been well defined in the pediatric population. The purpose of this study was to characterize the patterns of medial patellofemoral ligament (MPFL), vastus medialis obliqus (VMO), and osteochondral injury on magnetic resonance imaging (MRI) following first-time acute lateral patellar dislocation in pediatric patients. Methods: Following approval by the Institutional Review Board, a radiology query was performed to identify all patients between the ages of 11 and 18 years who underwent MRI following an acute first-time patellar dislocation over a 10-year period. The presence and location of injury to the MPFL, VMO, and chondral surfaces were evaluated on MRI images. A retrospective review of the patient's chart was conducted to confirm that clinical history was consistent with an acute patellar dislocation. Demographic data, including age at the time of injury, sex, knee affected, mechanism of injury, and recurrence of dislocation, were retrieved from the chart. The data were analyzed as a single cohort. Results: One hundred and eleven patients, including 56 males and 46 females with a mean age of 14.9 years (range, 11 to 18 y), were included. MRI demonstrated MPFL injury in 87 patients (78.4%). MPFL injury was present at an isolated patellar insertion in 34 patients (31%) and an isolated femoral insertion in 16 patients (14%). MPFL injury at more than one location was present in 37 patients (33%). VMO edema was present in 62 patients (56%), consistent with sprain or tear. Osteochondral fracture was identified in 38 knees (34%), with 25 from the medial patellar facet, 5 from the lateral femoral condyle, and 8 from both locations. Conclusions: Acute patellar dislocations remain a common injury in pediatric patients. The pattern of injury to the MPFL and VMO on MRI has not been described in a pediatric population. The triad of injury to the MPFL, VMO, and chondral surfaces should be recognized and understood, particularly when surgical reconstruction is necessary. Level of Evidence: Level III.


Analysis zhengcun mine field,confined fissure water aquifer of the Ordovician system calcarenite karst is strongly rich water,confined fissure water aquifer of Taiyuan formation calcarenite karst is strongly rich water,confined fissure water aquifer of Shanxi formation calcarenite karst is strongly rich water.During the coal mine to the design and produce,filling water mainly come from underground water and floor roadway water of aquifer filled drectly with water by coal seam top(underground water coming from Taiyuan formation calcarenite).When there are fault,Ordovician system calcarenite water should be prevented from going into shaft.


Objective To investigate the effects of dental treatment on the quality of life(QOL) and activities of daily living(ADL) in the elderly. Methods A controlled study was conducted from November 2012 and January 2013 to determine the effects of dental treatments on the QOL and ADL in 40 elderly adults, who were allocated into two groups: the intervention group(n=20) and the control group(n=20). Their mean age was(78.2±7.3) years. The elderly adults from the intervention group were treated by dental treatment according to the oral health. Outcome data were collected 8 weeks after baseline in both groups. QOL and ADL were assessed using General Oral Health Assessment Index(GOHAI) and Functional Independence Measure(FIM). Results The intervention group, which had received dental treatment, showed statistically significant difference in GOHAI scores and the expression function scores of FIM between baseline and 8 weeks after baseline(both P0.05). Data showed that dental treatments significantly increased the GOHAI scores and the expression function scores of FIM after considering the confounding factors(both P0.05). Conclusion Dental treatments increase the oral health-related QOL and the expression function in the ADL. Promoting dental care service at nursing facilities may be beneficial for maintaining the residents' QOL.


The present volumes provide up-to-date and state-of-the art knowledge of the manufacturing science and engineering, including: Kinematic, Dynamic and Static Analysis, Vibration, Noise Analysis and Control, Mechanical Transmission. Theory and Applications, Reliability of Machines and Mechanisms, Sensor Technology, Electromechanics and Mechatronics, Industrial Robotics, Advanced NC Techniques and Equipment, Organization and Management of Modern Manufacturing, etc. The volumes will not only provide the readers a broad overview of the latest advances but also provide the researchers a valuable summary and reference in this field.


Type 1.5 diabetes (1) is characterized by rapid loss of β-cell function, failure of oral agents, and acquirement of insulin requirement (2,3). These patients have islet cell antibodies (ICAs), GAD65 autoantibodies (GAD65Abs) (4,5,6), or both, indicating an underlying autoimmune pathogenesis. Therefore, the question of whether type 1.5 diabetes represents a separate clinical disease or a slowly progressive form of type 1 diabetes has been raised (7,8). The aim of the present study was to investigate whether GAD65Ab epitopes in type 1.5 diabetic patients differ from those found in type 1 diabetic patients and other GAD65Ab-positive phenotypes.

Type 1.5 diabetic patients ( n = 34) were identified as GAD65Ab-positive type 2 diabetic …


A visual sense system for robots which can measure and recognize 3-D objects is proposed. This robot vision system is capable of recognizing machine parts moving on a line so that an automated transferring and assembly system with high flexibility and no dependence on external peripheral equipment can be realized. This system possesses two remarkable features. One is the measuring technique, which can effectively remove the false 3-D information due to mirror reflection using laser slit beams from two directions. The other is the technique of carrying out the recognition of polygonal surfaces by p-type Fourier descriptor, area and perimeter, and, further, the recognition of objects based on aspect graphs, using multistage neural networks. As compared with the conventional recognition method, the speed and accuracy of recognition rose a step.<<ETX>>


In recent decades, the freshwater alga Gonyostomum semen (Ehrenberg) Diesing has increased in abundance and distribution, which has created problems regarding the use of lakes for drinking water and recreation. Increases in lake dissolved organic carbon (DOC; browning) and climate warming are among current hypotheses that explain the phenomenon of in creased abundance of G. semen. A replicated, multifactorial laboratory experiment was performed in order to test the effects of DOC and light quality and irradiance on growth of G. semen in 96-well plates. Each well had a separate light source, creating a gradient of irradiance (10− 140 μmol photons m−2 s−1) and wavelength (white, red, green and blue), combined with a DOC gradient (0−50 mg C l−1), all within representative ranges for the summer epilimnion in boreal waters. The experiment showed that growth of G. semen was significantly enhanced by the addition of DOC. No growth response relating to wavelengths was found, but where irradiance was inhibitory, a shading effect from DOC was evident. A composed response to increases in DOC suggests a versatility of G. semen that gives it a competitive advantage over other phytoplankton in humic lake ecosystems. Hence, further increases in abundance and bloom frequency of G. semen as browning continues in boreal lakes are to be expected.


The level of teachers' disaster preparedness in schools is one thing that influences the impact of disasters on children with disabilities, especially earthquakes, which can occur at any time, including during school hours. Therefore, this study aims to determine the description of earthquake disaster preparedness for special school teachers. This study used a quantitative descriptive method with a total sample of 37 teachers at Cileunyi State SLB, and the total sampling technique used was this study. Preparedness measurement for SLB teachers uses instruments modified according to research needs. Data analysis with frequency distribution and results were grouped into ready and unprepared categories. The results showed that 86.5% of teachers were categorized as 'ready'. The best preparedness parameter is disaster knowledge, while the lowest is disaster warning. From the study results, it can be concluded that most SLB teachers are categorized as ready to face earthquake disasters. However, it is expected that efforts to improve aspects of disaster warning can be carried out, such as providing disaster warning tools, especially for children with disabilities.


K g e r t o n Hobb, g e n e r a l m a n a g e r of t h e s i x t h b i e n n i a l E n g i n e e r i n g S h o w , a n n o u n c e d W e d n e s d a y t h a t t h e o r g a n i z a t i o n of d e p a r t m e n t m a n a g e r s , t h e i r a s s i s t an t i ) , a n d o t h e r o f f i c i a l s w o u l d bo c o m p l e t e d t h i s y e a r . A c c o r d i n g t o H o b b , t h e r e wil l be a m a n a g e r a n d a s s i s t a n t m a n a g e r fo r e a c h of t h e f o u r s c h o o l s of e n g i n e e r ing. E a c h m a n a g e r will be a m e m b e r of t h e s e n i o r c l a s s a n d will be e l e c t e d by t h e s e n i o r s of h i s d e p a r t m e n t , w h i l e t h e a s s i s t a n t m a n a g e r s will be j u n i o r s a n d will b e e l ec t ed by t h e j u n i o r s of t h e f o u r d e p a r t m e n t s . T h e d e p a r t m e n t s of P h y s i c s , Biology, A r c h i t e c t u r e i i n d E c o n o m i c s wi l l e a c h h a v e a m a n a g e r , a p p o i n t e d by G e n e r a l M a n a g e r Hobb . O t h e r o f f i c i a l s n e c e s s a r y to t h e show will be a p p o i n t e d by Hobb, M e e t i n g s of t h e e n t i r e s h o w s t a f f will b e he ld i m m e d i a t e l y p r e c e d i n g e a c h E n g i n e e r i n g S o c i e t y m e e t i n g , w h e r e p l a n s f o r t h e s h o w will be d i s c u s s e d a n d p e r f e c t e d . Miss Lillian Horlock of Houston, Texas , will represent the Rice Inst i tute at the All College Hevlew to be held at. the T e x t s State Fair, Dallas . Miss Horlock, a senior, w a s e lec ted at a m a s s m e e t i n g of coeds Thursday. The Mis se s Mar jorie Nicks. H o m o i s e l l e Haden, and Edytlie Wester f i e ld , were in the run-off with Miss Horlock.


There has recently been increased interest in media with near-zero permittivity. It is well known that the noble metals possess this property close to a definite frequency in the optical region. It is shown in this paper that a composition can be selected for a composite for which the permittivity is close to zero at the given frequency, with the losses being of the same order as for the noble metal at the frequency at which the real part of its permittivity goes to zero.


Has been followed the dinamik of the chemical composition of pepers the populations pepers and physiological repenss. Acording to attained result could be concluded that, ther are considerable differences into the contain of chemical substances which are higher in comparison to the control pepers at different stage of the ripeness.


One of the main issues of wave energy nowadays is the oscillation of the generated power, which is due to the oscillating nature of the waves. These power fluctuations may have an important undesired impact on the electrical grid. This paper proposes a system that compensates power oscillations in wave energy applications by means of a supercapacitor-based energy storage system. A laboratory test bench is used to emulate wave power oscillations and to partially suppress them. The paper describes the control strategy implemented in the test bench and includes experimental results for regular waves.


Interrelations between EU law and domestic law – Concept of a norm-based compound structure – Intertwinement of legal norms and legal orders – Combined normativity – Multi-level structure within the legal norms – Primacy, supremacy and ranking of EU law and domestic law – Structural principles guiding the relationship between EU law and domestic law – Principles of uniformity and constitutional identity


Objective To evaluate autonomic nerve function patients with neoplasms.Methods For June 2002 to January 2005,72 patients were randomly divided to neoplasm group 36 cases and normal group 36 cases.Time domain methods of heart rate variability tests were performed.Results SDNN(67.53±20.69)ms,(132.72±25.15)ms,SDANN(57.61±19.52)ms,(111.50±27.19)ms,rMSSD(17.72±9.72)ms,(35.17±8.17)ms,PNN_ 50 (5.00±5.45)%,(14.70±5.65)%.were significantly lower in patients with neoplasms than those in normal subjects(P0.01).Conclusion The severe neoplasms lesion is,the worse heart rate variability is.


The management of production is faced with ever greater challenges as global competion mounts. The problems revolve around the paradox of flexibility and productivity in the organization of production: how to compete on price while retaining the capability to respond quickly to market changes; how to develop new products faster without jeopardizing product integrity; how to increase quality while reducing costs. The recent research on lean production has explored some of these questions in the context of the motor industry. This book takes a broader audit of these issues across the full range of the metalworking sector in the United Kingdom. Focusing on the engineering/manufacturing interface, the research presented here explores how 15 leading British firms are facing up to the challenges of the 90s.


In Rival Enlightenments Ian Hunter argues convincingly that there was not one comprehensive German Enlightenment, represented by Kant, but two irreducible and rival enlightenments: the metaphysical Enlightenment of Leibniz and Kant and the non-transcendental, civil Enlightenment of Pufendorf and Thomasius. Hunter's study frees us from a dominant way of taking up the question, 'What is Enlightenment?', and enables us to see that there is a plurality of possible answers.


Let $\dot{\mathbf{U}}(\widehat{\frak{sl}}_n)$ be the modified quantum affine $\frak{sl}_n$ and let ${\bf U}(\widehat{\frak{sl}}_N)^+$ be the positive part of quantum affine $\frak{sl}_N$. Let $\dot{\mathbf{B}}(n)$ be the canonical basis of $\dot{\mathbf{U}}(\widehat{\frak{sl}}_n)$ and let $\mathbf{B}(N)^{\mathrm{ap}}$ be the canonical basis of ${\bf U}(\widehat{\frak{sl}}_N)^+$. It is proved in \cite{FS} that each structure constant for the multiplication with respect to $\dot{\mathbf{B}}(n)$ coincide with a certain structure constant for the multiplication with respect to $\mathbf{B}(N)^{\mathrm{ap}}$ for $n<N$. In this paper we use the theory of affine quantum Schur algebras to prove that the structure constants for the comultiplication with respect to $\dot{\mathbf{B}}(n)$ are determined by the structure constants for the comultiplication with respect to $\mathbf{B}(N)^{\mathrm{ap}}$ for $n<N$. In particular, the positivity property for the comultiplication of $\dot{\mathbf{U}}(\widehat{\frak{sl}}_n)$ follows from the positivity property for the comultiplication of ${\bf U}(\widehat{\frak{sl}}_N)^+$.


By Anne Stobart In a series of posts I have explored how we can know whether herbs might have really worked. It seems quite a while since the first post where I raised some historiographical questions (Part 1). In this eighth and last post of the series I want to conclude with (a) an overview of whether the herbs in a selected recipe might have had some efficacy and (b) a protocol for how historical researchers can approach the question of 'Did the herbs work?'. Did the herbs work in this rec...


© Author(s) (or their employer(s)) 2022. No commercial reuse. See rights and permissions. Published by BMJ. INTRODUCTION Described as 'unwritten rules', social norms affect how we interact with others, define which practices we regard as acceptable and serve as heuristics that simplify our decisionmaking. Norms evolve as shared practices, then become embedded within social groups; once established, they shape and reinforce perceptions of commonly practised behaviours (ie, descriptive norms) that attract social approval or disapproval (ie, injunctive norms). Because normative practices may define social group membership and serve as markers of identity and belonging, they become selfenforcing and help to attract new members. Environments play a critical role in enabling and supporting practices, and thus in creating and embedding social norms. For example, dispensing cigarettes to soldiers and providing ashtrays in public areas signalled smoking's acceptability, reinforced its normativity within specific settings and helped entrench it as a social practice. However, environments may also discourage and extinguish social practices. More recently, smokefree signage has declared that smoking is not acceptable within designated settings, 10 while removal of large instore tobacco displays sharply differentiated tobacco from normal consumer goods. 12 Lopez et al's fourphase model of the smoking epidemic describes how social norms changed as smoking practices diffused and after knowledge of smoking's harms increased. During the innovation and establishment phase, smoking's social acceptance increased, followed by rapidly increasing prevalence as new population groups adopted smoking. 13 Smoking prevalence peaked near the end of the second phase, then declined as knowledge of its harms emerged, prompting regulation, stimulating cessation and reducing its social acceptability. Prevalence declined further in the final phase as evidence of smoking's health risks grew and denormalisation, or loss of social acceptability, increased. Western countries, many of which have strong smokefree policies, provide the clearest illustration of these phases, which are more apparent in highincome countries than in low/middleincome countries. In this commentary, we draw on Lopez et al's model to outline how smoking—using commercially produced and supplied tobacco—evolved as a socially normative practice. We then discuss its subsequent relocation outside accepted social boundaries, review smoking denormalisation and its implications, and propose a fifth phase: the endgame phase. We conclude by considering tobacco companies' rapidly evolving product array and quest for renormalisation, and explore how the industry's renewed efforts to influence social norms could affect tobacco endgame strategies and people who smoke.


BACKGROUND AND STUDY AIMS
The main complication associated with biliary stenting is stent occlusion. This study tested the hypothesis that bilioduodenal reflux may play a crucial role in stent clogging.

PATIENTS AND METHODS
Plastic stents in 100 consecutive patients with various biliary disorders were investigated macroscopically and cytologically.

RESULTS
In 37 patients with elective stent extraction, the only risk factor for stent occlusion was the duration of stenting. Plant material was found as a consequence of duodenobiliary reflux in 38 of the 89 stents with any stent content. In patients who had two stents, the stent content was identical in eight of 14 cases.

CONCLUSIONS
In addition to other mechanisms of biliary stent occlusion, duodenobiliary reflux appears to play an important role. A stent design capable of at least partly preventing this type of reflux might be of clinical benefit.


Introduction. The regional aspect of regulating the innovative development of Ukraine's economy is an important and topical issue. The innovation potential of the regions is the main component of the effective functioning of enterprises, industries and is a basic characteristicі of their innovation.
The purpose of this article is to study the components of the regulation of regional innovation development.
Results. Today in Ukraine there is a rapid rise in unemployment and impoverishment of the population, which threatens significant social upheavals, so it is necessary to implement measures that can change the economic situation in the country for the better. One of such anti-crisis measures is the innovative development of regions and enterprises of the country. Regional innovation development is usually declared in many state and regional programs and projects of scientific, technical and innovative development programs. However, it was found that more than 50% of all innovative developments in Ukraine are in five regions: Kharkiv, Dnipropetrovsk, Zaporzhizhia and Lviv regions, as well as the capital of our country, Kyiv. As for other regions of Ukraine, they are reluctant to allocate funds for the research and development, in particular Volyn, Donetsk, Rivne, Ternopil and Khmelnytsky regions. The transition of the economy to an innovative model of development in modern conditions has no alternatives, as activity in the innovation sphere is currently perhaps the most important factor in economic growth and ensuring the competitiveness of economic entities.
Conclusions. Regulation of innovation development at the regional level requires the formation of an effective organizational structure of management, through which it is possible to analyze, coordinate and forecast innovation. The use of the mechanism of public-private partnership will ensure the overcoming of contradictions between public and private interests and will create a basis for attracting knowledge and experience of management.
Key words: innovations, regional innovative development, innovative developments.


Devices constructed with interdigitated surface electrodes are widely used in integrated optics to produce electrooptic switches, deflectors, and modulators as well as to launch surface acoustic waves. To be able to fabricate devices with the desired characteristics, it is essential to know the electric field that is produced in the material under the interdigitated electrodes. The spatial distribution of the electric field produced by a voltage applied to a set of interdigitated electrodes on the surface of an anisotropic crystal such as lithium niobate is calculated using rigorous electromagnetic theory. The effects of the electrode width, period, and thickness are presented. Variations with crystal orientation are analyzed. The presence of a buffer layer such as isotropic silicon dioxide is included and the effects of its thickness are presented. The resulting distributions of refractive index and strain are calculated and analyzed in terms of amplitude and harmonic content.


The scientific community is modeled as a social interaction system in attempt to understand how the community is stratified via research productivity.Based on the rational and habitual behavior of individual scientists,the interaction structure is simplified to the dual functioning of the two major tendencies: role-performing(mainly producing research papers) and approval-granting tendencies of the actors.The dynamics of this interaction,under certain structural and boundary conditions,generates stratification of research productivity.


For a nondecreasing score function having finitely many jump-discontinuities. a representation of M-estimators with the second order asymptotic distribution is established. and the result is also extended to one-step versions of M-estimators.


The advent of triptans in the 1990 s changed the approach to treating the migraine sufferer. Before triptan drugs, an acute attack of migraine was treated with drugs to put the patient to sleep until the migraine passed. This rendered the patient unable to resume activities such as school or work. Migraineurs had significant morbidity from treated as well as untreated attacks. With the use of this class of medications, headache could be treated quickly without the accompanied sedation from the medications. This has allowed people to get back to their busy lives, and migraine disability from medications has been lowered. Unfortunately, pediatric triptan trials have for the most part failed to demonstrate efficacy when compared to placebo. Nevertheless, these drugs are used for children and adolescents without FDA approval. Study design and consent adapted form adult studies may have made the placebo response rate higher than it needed to be. Drug Dev Res 68:346–349, 2007. © 2007 Wiley‐Liss, Inc.


In this twenty-first century, leadership qualities are paramount for fostering organizational culture and employee performance. This study penetrated the negative aspects of leadership qualities 'dark-triad of leadership' and its impact on team members. The hypotheses were developed from a thorough literature review on dark triad traits namely Narcissist, Machiavellian, and Psychopath. To reveal the impact of traits amongst team members, the Emirati educational sector was selected, and questionnaires were distributed amongst different strata by the random sampling technique. The responses were analyzed using SPSSv27. The analysis validated the reliability of the data and confirmed the hypotheses. Furthermore, it illuminates the intricate and challenging field of leadership research. Indeed, the study can develop organizational culture and employee performance.


Most previous studies have focused on the addition of nanoparticles of silicon dioxide, calcium carbonate, aluminium oxide, tin(IV) oxide or calcium silicate hydrate to speed up cement hydration. I...


The utilization of benzodiazepines and antipsychotics amongst senior citizens in the community and in long-term care has long been a concern for families and health care providers. The two studies presented in this thesis examined prescription patterns in seniors over sixty-five; first over time, then over geographical area. The use of benzodiazepines and antipsychotics remained stable over the three years of the study. Within the community, benzodiazepines and antipsychotics were also more prescribed in urban than rural areas. The difference in prevalence of benzodiazepine prescriptions in long-term care facilities was significant depending on the regional authority, whereas it was not significant for antipsychotic prescriptions. This research into the utilization of benzodiazepines and antipsychotics in the province is valuable because it provides a more thorough examination into utilization than has been previously undertaken in Newfoundland and Labrador.


High reliability applications for high performance computing, military, medical and industrial applications are driving electronics packaging advancements toward increased functionality with decrea...


Characterization of surface–groundwater interaction is an increasingly useful skill for riverine ecologists and water resource managers interested in the dynamics of water, nutrient, and micro‐organism exchange at the reach scale, as it can be used to better represent point‐scale processes within larger catchment‐scale models. This study describes a method for predicting the nature of reach‐scale surface–groundwater interaction, using the random forest (RF) machine learning technique with national‐scale geology, hydrology, and land use data. Observed stream flow depletion and accretion surveys from riparian areas and spring‐line flow accretion surveys were also used. The RF model allowed prediction of observed losing and gaining reaches with a high prediction accuracy ("out‐of‐bag" error < 10%). The performance of the model, however, was found to be dependent on the geographic administrative region. The model was also found to be sensitive to slope, distance to headwater, distance to coast, and underlying geological characteristics. When applied in New Zealand, this approach yielded a realistic conceptual representation of national surface–groundwater dynamics that are subsequently being used to inform a national‐scale hydrological model.


One of the core issues regarding informational privacy in the 21st century is the issue of information sharing. The question is not whether the state will engage in information sharing practices, or even whether it should. The real question is whether such practices will be subject to constitutional scrutiny and thereby required to meet a rigorous standard of justification. The Canadian Supreme Court constitutional exhibits a number of key ambiguities regarding privacy that suggest courts will find it too easy to hold that such practices do not violate a reasonable expectation of privacy. First, the court shifts between a descriptive and a normative approach to defining privacy. Second, its descriptive approach often conflates the threshold question of defining privacy with the subsequent question of balancing privacy with other important social goals. Third, some of the more normative elements that do provide content to the reasonable expectation of privacy are norms of confidentiality, which, although related, are not the same thing as norms of privacy. This paper outlines these ambiguities and shows how they operate to discount privacy within the regulatory context but in a manner that is particularly problematic if applied without regard to the issues arising from information sharing.


Computers have been successfully used in group theory for a good many years to calculate the structure of a group. They have also been used to either prove or disprove a number of conjectures since they allow examination of large examples. Moreover, computers have been instrumental in the discovery of a number of new groups.
 Few areas in algebra have been applied as extensively to other areas of mathematics and the physical sciences as Lie algebras. Applications almost invariably call for extensive computational work. There are strong parallels between the structure of groups and the structure theory of Lie algebras. In view of the successful application of computers to handle computational problems in group theory, it was reasonable to consider an analogous approach in Lie algebras.


Objective:To explore the clinical feature,treatment and prognosis of gestational trophoblastic tumor. Methods:Retrospectively analyzed the clinical pathological materials of 11 patients with carcinoid and malingnant gestational trophoblastic tumor treated from January.1997 from December 2008 in our hospital.Results:fn the 28 cases, 1 case of erosive hydatidiform mole did not relapse after the chemical treatment of 3 years' survey;2 cases went back to the inland due to"lung transference and continuous hydatidiform mole";5 cases was still in the follow-up survey; the last had been cured after follow-up survey.Conclusion:Gestational trophoblastic tumor have a higher rate or happening; The carcinoid tumor has a better prognosis,yet people should guard its initial bad change;malignant gestational trophoblastic tumor can be cured after the positive chemical treatment.


The stability of the base structure for the fracture rock-mass of great stress area in Jinchuan lean ore area mining by natural caving process is analyzed by the three-dimensional elastic-plasticity finite element numerical analogy. The results show that the great plastic yield areas and pull failure areas are formed in the base structure with caved area extends. The stability of the base structure for nature caved mining can be assured by use of the gradual supports of draw drifts.


Cemented soils or concrete are usually cured under moisture conditions and their strength increases with curing time. An insufficient supply of water to cemented soils can contribute to hydration process during curing, which results in the variation of bonding strength of cemented soils. In this study, by the consideration of in situ water supply conditions, cemented sand with cement ratio less than 20% was prepared by air dry, wrapped, and underwater conditions. A series of unconfined compression tests were carried out to evaluate the effect of curing conditions on the strength of cemented soils. The strength of air dry curing specimen was higher than those of wrapped cured specimen when cement ratio was less than 10%, whereas it was lower when cement ratio was greater than 10%. Regardless of cement ratio, air dry cured specimens were stronger than underwater cured specimens. A strength increase ratio with cement ratio was calculated based on the strength of 4% cemented specimen. The strength increase ratio of air dry cured specimen was lowest and that of wrapped and underwater cured ones increased by square. Strength of air dry cured specimen dropped to maximum 30% after wetting when cement ratio was low. However, regardless of cement ratio, strength of wrapped specimens dropped to an average 10% after wetting.


Labetalol, an α‐ and β‐adrenergic receptor‐blocking agent, was studied as a hypotensive agent during halothane (mostly 0.5 vol.%)‐N2O‐fentanyl‐d‐tuhocurarine anaesthesia with a head‐up tilt of 5 degrees in 41 patients undergoing middle ear microsurgery. After the mean initial dose of 0.3 mg/kg, the mean need for labetalol ranged from 0.05 to 0.07 mg/kg at 30 ± 5‐min intervals. The mean duration of the hypotensive period was 102 min. During the hypotension, the average mean arterial pressure ranged from 59 to 62 mmHg (7.9‐8.3 kPa) and the mean heart rate from 61 to 66 b.p.m. After labetalol the maximum cardiac output decrease was 7%. Before labetalol the mean Pao2 value was 158 mmHg (21.1 kPa) and during hypotension it ranged from 145 to 149 mmHg (19.3–19.9 kPa) when Fio2 was 40%. The only peroperative side effects were ECG changes (middle junctional rhythm and sinus bradycardia) which occurred in 10% of the patients. The mean value for the degree of haemostasis rated by the otologist on a visual analogue scale between poor (0 mm) and excellent (100 mm) was 91 mm. The patients were able to open their eyes and to give their names 8–9 min after the end of anaesthesia. After extubation the patients were normotensive and there were no clinically significant changes in the cardiovascular parameters during the 4‐h recovery room period. Acid‐base status showed slight metabolic acidosis. The most common postoperative side effects were nausea only and nausea + vomiting, which occurred in 39% and 20% of the patients, respectively. It is concluded that labetalol produced stable, easily controllable hypotension without a compensatory rise in the heart rate, with minimal effect on peroperative Pao2 value or cardiac output, as well as good operating conditions. The postoperative course was uneventful with the exception of a high incidence of nausea and vomiting, most probably due to the operation rather than to the anaesthesia.


Findings from a study of Portuguese information-documentation professionals point to a major concern: career management in an age of uncertainty and its impact on professionals' dilemmas, for both new and old generations. With the intent of learning more about this profession in different generations, the following research question guided this study: what conflicts and dilemmas exist between the new information society skills and the demands of constructing a life-long career? To address this question, the study relied on interviews with librarians who have been working since 1973. The respondents came from research libraries and public libraries. The findings from this study highlight the experiences and expectations of professionals of maintaining professional success, and show how they have faced their difficult decisions as they planned their careers. These decisions concern how to deal with career choices and to manage professional training and skills development. This analysis may contribute to understanding inter-generational discourse relating professional and personal concerns.


Fatty acid/SiO_2 composite,a phase change material(PCM),was prepared by sol-gel method.PCM changes phase from solid to liquid inside SiO_2 gel hole,and appearance of composite is always solid.The lightweight PCM wallboard was prepared by bonding PCM composite on expanded polystyrene(EPS) board,so that the shortcoming of low thermal storage capacity of common lightweight wall is overcome.Thermal insulation and temperature control experimentation were conducted by models fabricated of two kinds lightweight wall-materials with or without PCM,the result shows that the thermal-storing capacity of lightweight PCM wall-material could be greatly improved.


Full-scale fire experiments were conducted in the Yingzuiyan Tunnel and the development of smoke layer were measured under different longitudinal wind speed conditions. Results showed that the different longitudinal wind speed and fire size would influence the smoke layer falls deeply. Comparing the two factors,longitudinal wind speed takes more important role. When fire source locates at high position,the expansibility of smoke layer is enlarged and adverse smoke flow happens outside of a certain distance from fire source. A slight stack effect is produced in some gradient of tunnel,which conducts the flow to backward position is accelerated. This character could be introduced to improve the effect of smoke extract during tunnel design process.


Abstract Background Currently, there is no specific drug for the treatment of COVID-19. Therapeutic benefits of intravenous immunoglobin (IVIG) have been demonstrated in wide range of diseases. The present study is conducted to evaluate the safety and efficacy of IVIG in the treatment of COVID-19 patients with moderate pneumonia. Methods An open-label, multicenter, comparative, randomized study was conducted on COVID-19 patients with moderate pneumonia. 100 eligible patients were randomized in 1:1 ratio either to receive IVIG + standard of care (SOC) or SOC. Results Duration of hospital stay was significantly shorter in IVIG group to that of SOC alone (7.7 Vs. 17.5 days). Duration for normalization of body temperature, oxygen saturation and mechanical ventilation were significantly shorter in IVIG compared to SOC. Percentages of patients on mechanical ventilation in two groups were not significantly different (24% Vs. 38%). Median time to RT-PCR negativity was significantly shorter with IVIG than SOC (7 Vs.18 days). There were only mild to moderate adverse events in both groups except for one patient (2%), who died in SOC. Conclusions IVIG was safe and efficacious as an adjuvant with other antiviral drugs in the treatment of COVID-19. The trial was registered under Clinical Trial Registry, India (CTRI/2020/06/026222).


SUMMARY A new positioning technique is presented, based on MR- and CT imaging with surface markers applied to the skin of the specimen. With this technique, the required anatomic section for cryosectioning can be defined accurately Plastinated slices, of 2 mm thickness, with the correlating MR-, CT-, and US images of double-oblique coronal imaging of the shoulder are shown. The method is equally applicable to all parts of the body and makes comparison of structures in correlative anatomic studies easier and more accurate.


After years of neglect, a renewed interest in beauty developed among many Western art critics, art practitioners and theorists of aesthetics in the 1990s. Beauty had fallen from favour in part because it was deemed politically and ethically suspect, both as complicit with the sociopolitical structures that yielded WWI and as a tool of oppression wielded against women and minorities. One wonders, however, whether the baby was thrown out with the bathwater. Even granted that beauty has been damaging in the ways alluded to, can it yet be ethically helpful in ways that were lost when we ceased to attend to beauty (at least in the realms of institutional art and aesthetic theory if not in the day to day)? What ethical benefits might we have overlooked? The answer to this question depends partly on what one takes beauty to be. Beauty is a complex concept; there exist many competing and frequently contradictory accounts, often with deep roots, making the concept rife with internal contradictions. Rather than either attempt to reconcile conflicting accounts or address only one aspect of the concept, I will show that different sorts of relation to ethics emerge depending on how we approach beauty. I will present three different ways in which we can see beauty as related to ethics: beauty qua motivator of ethical relation, qua formal cause of ethical relation, and qua analogue of ethical relation.


This paper briefly describes the new principle about the classification of inimediate roof after its stabilities and main roof after the intensity of its weighing, as well as the floor based on its resistance and rigidity that are against supports to penetrate in coal face. These have been done on the basis of theory and measured data obtained from field observation. These classifications are very important for optimal determination of technique for control of surrounding rock-mass including the selection of supports, as well as the economic effect and safety during mining


Polypyrrole nanowire(nanotubes) is one kind of the most promising materials for multifunctional applications.A review is given on the methodology of the synthesis of polypyrrole nanowires(nanotubes),including the research progresses of template,free-template and self-assembling techniques.In addition,the application aspects of polypyrrole nanowires(nanotubes) in the fields of electrode,photoelectrochemistry and medicine are forecast.