text:
Research Topics
Genomes and Genes
neuromuscular diseases
Summary: A general term encompassing lower MOTOR NEURON DISEASE; PERIPHERAL NERVOUS SYSTEM DISEASES; and certain MUSCULAR DISEASES. Manifestations include MUSCLE WEAKNESS; FASCICULATION; muscle ATROPHY; SPASM; MYOKYMIA; MUSCLE HYPERTONIA, myalgias, and MUSCLE HYPOTONIA.
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Publications225 found, 100 shown here
- RNA-targeting approaches for neuromuscular diseasesFlorence Le Roy
Genethon, CNRS UEVE UMR8587 LAMBE, 1, rue de l Internationale, 91000 Evry, France
Trends Mol Med 15:580-91. 2009..These diverse strategies show tremendous therapeutic potential and several clinical trials have been initiated with Duchenne muscular dystrophy patients with promising results...
- Defective membrane remodeling in neuromuscular diseases: insights from animal modelsBelinda S Cowling
Department of Translational Medicine and Neurogenetics, Institut de Genetique et de Biologie Moleculaire et Cellulaire IGBMC, Illkirch, France
PLoS Genet 8:e1002595. 2012..This suggests (1) a common molecular pathway underlying these different neuromuscular diseases, and (2) tissue-specific regulation of these proteins...
- Animal models for genetic neuromuscular diseasesMariz Vainzof
Dept of Genetics and Evolutionary Biology, University of Sao Paulo, Sao Paulo, Brasil
J Mol Neurosci 34:241-8. 2008..Several animal models, manifesting phenotypes observed in neuromuscular diseases, have been identified in nature or generated in laboratory...
- Ryanodine receptor 1 mutations, dysregulation of calcium homeostasis and neuromuscular disordersSusan Treves
Dipartimento di Medicina Sperimentale e Diagnostica, Sezione Patologia Generale, Universita degli Studi di Ferrara, Via Borsari 46, 44100 Ferrara, Italy
Neuromuscul Disord 15:577-87. 2005....
- Coenzyme Q10 deficiencies in neuromuscular diseasesRafael Artuch
Biochemistry Department, Hospital Sant Joan de Deu, Barcelona, Spain
Adv Exp Med Biol 652:117-28. 2009..This review updates the clinical and molecular aspects of both types of CoQ deficiencies and proposes new approaches to understanding their molecular bases...
- Pulmonary complications of chronic neuromuscular diseases and their managementChristophe Perrin
Division of Pulmonary, Critical Care, and Sleep Medicine, Tufts New England Medical Center, Tufts University School of Medicine, 750 Washington Street, Boston, Massachusetts 02111 1526, USA
Muscle Nerve 29:5-27. 2004Chronic neuromuscular diseases may affect all major respiratory muscles groups including inspiratory, expiratory, and bulbar, and respiratory complications are the major cause of morbidity and mortality...
- Camptocormia: pathogenesis, classification, and response to therapyShaheda N Azher
Parkinson s Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, Houston, TX 77030, USA
Neurology 65:355-9. 2005....
- Development and application of stereo camera-based upper extremity workspace evaluation in patients with neuromuscular diseasesGregorij Kurillo
University of California at Berkeley College of Engineering, Department of Electrical Engineering and Computer Science, Berkeley, California, United States of America
PLoS ONE 7:e45341. 2012..A method to intuitively display and effectively analyze reachable workspace would not only complement traditional upper limb functional assessments, but also provide an innovative approach to quantify and monitor upper limb function...
- Severe respiratory syncytial virus (RSV) infection in infants with neuromuscular diseases and immune deficiency syndromesBernhard Resch
Research Unit for Neonatal Infectious Diseases and Epidemiology, Division of Neonatology, Paediatric Department, Medical University of Graz, A 8036 Graz, Austria
Paediatr Respir Rev 10:148-53. 2009..There is growing evidence of severe RSV disease in infants with neuromuscular diseases and immune deficiency syndromes...
- Force tracking system for the assessment of grip force control in patients with neuromuscular diseasesGregorij Kurillo
Faculty of Electrical Engineering, Laboratory of Robotics and Biomedical Engineering, University of Ljubljana, Trzaska 25, 1000 Ljubljana, Slovenia
Clin Biomech (Bristol, Avon) 19:1014-21. 2004..Tracking methods have been successfully used for the assessment of grip force control in stroke patients and patients with Parkinson's disease...
- Stem cell therapies for neuromuscular diseasesTerence A Partridge
Muscle Cell Biology Group, MRC Clinical Sciences Centre, Hammersmith Hospital, Du Cane Road, London, W12 0NN
Acta Neurol Belg 104:141-7. 2004..For the latter especially, we need a degree of improvement that can only come from a better understanding of the mechanisms involved...
- Fatigue and neuromuscular diseasesL Feasson
Unité de Recherche PPEH EA 3062, Faculte de Medecine Jacques Lisfranc, Université Jean Monnet, Saint Etienne, France
Ann Readapt Med Phys 49:289-300, 375-84. 2006To identify the role of fatigue, its evaluation and its causes in the pathophysiology context of acquired or hereditary neuromuscular diseases of the spinal anterior horn cell, peripheral nerve, neuromuscular junction and muscle.
- Alternatives to endotracheal intubation for patients with neuromuscular diseasesEmilio Servera
Rehabilitation and Ventilation Unit, Department of Respiratory Medicine, Hospital Clinico Universitario, Universitat de Valencia, Valencia, Spain
Am J Phys Med Rehabil 84:851-7. 2005..To evaluate the usefulness of continuous noninvasive mechanical ventilation and mechanical coughing aids to avoid endotracheal intubation and tracheostomy during episodes of acute respiratory failure in patients with neuromuscular disease...
- Neuromuscular diseases associated with chronic hepatitis C virus infectionJoerg Patrick Stübgen
Department of Neurology and Neuroscience, Cornell University Medical College New York Presbyterian Hospital, New York, NY 10065 4885, USA
J Clin Neuromuscul Dis 13:14-25. 2011..degrees of certainty, there is evidence of an association between chronic HCV infection and a variety of neuromuscular diseases. The pathogenesis of most extrahepatic diseases remains unclear but possibly includes HCV lymphotropism ..
- Activation of fast skeletal muscle troponin as a potential therapeutic approach for treating neuromuscular diseasesAlan J Russell
Preclinical Research and Development, San Francisco, California, USA
Nat Med 18:452-5. 2012..Troponin activation may provide a new therapeutic approach to improve physical activity in diseases where neuromuscular function is compromised...
- A novel modulation strategy to increase stimulation duration in neuromuscular electrical stimulationRyan J Downey
Department of Mechanical and Aerospace Engineering, University of Florida, Gainesville, Florida 32611 6250, USA
Muscle Nerve 44:382-7. 2011..The purpose of this study is to examine the effect of feedback-based frequency modulation on the closed-loop performance of the quadriceps during repeated dynamic contractions...
- Investigating the minimum required number of genes for the classification of neuromuscular disease microarray dataArgiris Sakellariou
Biomedical Research Foundation, Academy of Athens, and the Department of Informatics and Telecommunications, National and Kapodistrian University of Athens, Athens 115 27, Greece
IEEE Trans Inf Technol Biomed 15:349-55. 2011..Five feature selection methods on datasets from ten different neuromuscular diseases were utilized...
- Integrated radiation hybrid map of human chromosome 2p13: possible involvement of dynactin in neuromuscular diseasesD Korthaus
Developmental Biology, University of Bielefeld, Germany
Genomics 43:242-4. 1997The genes for the human neuromuscular diseases limb-girdle muscular dystrophy type 2B (LGMD2B) and Miyoshi myopathy are located on chromosome 2p13-p14, and two neuromuscular mutations of the mouse have been mapped to regions homologous to ..
- The diagnosis of mitochondrial muscle diseaseRobert W Taylor
Mitochondrial Research Group, School of Neurology, Neurobiology and Psychiatry, The Medical School, University of Newcastle upon Tyne, Framlington Place, Newcastle upon Tyne NE2 4HH, UK
Neuromuscul Disord 14:237-45. 2004..Here, we describe a step-by-step approach to the clinical and laboratory diagnosis of mitochondrial muscle disease, highlighting the many potential problems that can hinder reaching the correct diagnosis...
- Next generation sequencing for molecular diagnosis of neuromuscular diseasesNasim Vasli
IGBMC Institut de Génétique et de Biologie Moléculaire et Cellulaire, 1, rue Laurent Fries, BP10142, 67404, Illkirch, France
Acta Neuropathol 124:273-83. 2012..An earlier genetic diagnosis should provide improved disease management and higher quality genetic counseling, and ease access to therapy or inclusion into therapeutic trials...
- Neuromuscular diseases and disorders of the alimentary systemVinay Chaudhry
Department of Neurology, Johns Hopkins University School of Medicine, 600 North Wolfe Street, Meyer 6 119, Baltimore, Maryland 21287, USA
Muscle Nerve 25:768-84. 2002This review outlines the relationship and interaction between neuromuscular diseases and disorders of the alimentary system. Neuromuscular manifestations of gastrointestinal and hepatobiliary diseases are first considered...
- Mitochondrial respiratory chain dysfunction in various neuromuscular diseasesS Jongpiputvanich
Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand
J Clin Neurosci 12:426-8. 2005..function and the occurrence of mitochondrial respiratory chain dysfunction were determined in various neuromuscular diseases. The mitochondrial complexes I-V and citrate synthase in the skeletal muscle taken from 75 orthopaedic ..
- A motor function measure for neuromuscular diseases. Construction and validation studyCarole Berard
Department of Paediatric Rehabilitation, l Escale, Centre Hospitalier Lyon Sud, France
Neuromuscul Disord 15:463-70. 2005A new scale for motor function measurement has been developed for neuromuscular diseases. The validation study included 303 patients, aged 6-62 years...
- Expiratory flow maneuvers in patients with neuromuscular diseasesJohn R Bach
Department of Physical Medicine and Rehabilitation, UMDNJ New Jersey Medical School, 150 Bergen Street, Newark, NJ 07871, USA
Am J Phys Med Rehabil 85:105-11. 2006....
- [Noninvasive mechanical ventilation in patients with neuromuscular diseases and in patients with chest restriction]C Lisboa
Departamento de Enfermedades Respiratorias Pontificia Universidad Católica de Chile Santiago Chile
Arch Bronconeumol 39:314-20. 2003
- Microvasculopathic neuromuscular diseases: lessons from hypoxia-inducible factorsStefan Probst-Cousin
Department of Neurology, Klinikum Bremen Ost, Bremen, Germany
Neuromuscul Disord 20:192-7. 2010..These observations suggest that the upregulation of hypoxia-related proteins may represent an adaptation mechanism of neuromuscular tissues to immune mediated deprivation of the blood supply...
- Histochemical and immunohistological approach to comparative neuromuscular diseasesOrlando Paciello
Department of Pathology and Animal Health, University of Naples Federico II, Naples, Italy
Folia Histochem Cytobiol 47:143-52. 2009The broad category of neuromuscular diseases covers conditions that involve the weakness or wasting of the body muscles. These problems may occur in the spinal cord, the peripheral nerves or the muscle fibers...
- Chronic respiratory care for neuromuscular diseases in adultsN Ambrosino
Dipartimento Cardio Toracico, Azienda Ospedaliero Universitaria Pisana, Pisa, Italy
Eur Respir J 34:444-51. 2009b>Neuromuscular diseases (NMD) may affect respiratory muscles, leading to respiratory failure. Studies show that long-term noninvasive mechanical ventilation (NIV) improves symptoms, gas exchange, quality of life and survival...
- Construction and validation of a quality of life questionnaire for neuromuscular disease (INQoL)K A Vincent
Department of Neurology, King s College Hospital and the Guy s, King s and St Thomas School of Medicine, King s College, University of London, UK
Neurology 68:1051-7. 2007..Because there is no muscle disease specific measure of quality of life (QoL), we wanted to develop and validate an individualized muscle disease specific measure of QoL for adults suitable for both clinical and research use...
- Efficacy and tolerance of gastrostomy feeding in pediatric forms of neuromuscular diseasesDavid Seguy
Department of Nutrition, University Hospital and Medical School, Lille, France
JPEN J Parenter Enteral Nutr 26:298-304. 2002..PEG) is a simple and reliable method, but there are few data about its use in pediatric forms of neuromuscular diseases (NMD)...
- Muscle-fiber apoptosis in neuromuscular diseasesDominique S Tews
Edinger Institute, Johann Wolfgang Goethe University Hospital, Deutschordenstrasse 46, D 60528 Frankfurt am Main, Germany
Muscle Nerve 32:443-58. 2005..In contrast, certain neuromuscular diseases seem to involve characteristic expression patterns of apoptosis-related factors and pathways...
- The prion protein in human neuromuscular diseasesGabor G Kovacs
National Institute of Psychiatry and Neurology, Budapest, Hungary
J Pathol 204:241-7. 2004..In addition, our observations suggest that PrPC may have a general stress-response effect in various neuromuscular disorders...
- Initiation of home mechanical ventilation in children with neuromuscular diseasesSuchada Sritippayawan
Division of Pediatric Pulmonology, Childrens Hospital Los Angeles, California 90027, USA
J Pediatr 142:481-5. 2003..often home mechanical ventilation (HMV) is instituted electively in children with respiratory failure from neuromuscular diseases and whether there were opportunities to discuss therapeutic options with patients/families before ..
- Interferon-alpha/beta-mediated innate immune mechanisms in dermatomyositisSteven A Greenberg
Department of Neurology, Division of Neuromuscular Disease, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
Ann Neurol 57:664-78. 2005....
- Immunological methods for the analysis of protein expression in neuromuscular diseasesMariz Vainzof
Departamento de Biologia, Centro de Estudos do Genoma Humano, Instituto de Biociencias, Universidade de Sao Paulo, Sao Paulo, Brazil
Methods Mol Biol 217:355-78. 2003
- [A motor function measurement scale for neuromuscular diseases - description and validation study]C Berard
Service de Rééducation Pédiatrique l Escale, Hospices Civille de Lyon, Centre Hospitalier Lyon Sud, Pierre Benite
Rev Neurol (Paris) 162:485-93. 2006A new scale for motor function measurement has been developed for neuromuscular diseases. After the study of a preliminary and a first version, the validation study included 303 patients, aged 6 to 62 years...
- Exercise therapy and other types of physical therapy for patients with neuromuscular diseases: a systematic reviewEdith H Cup
Department of Occupational Therapy, Research Centre of Allied Health Care, Nijmegen, The Netherlands
Arch Phys Med Rehabil 88:1452-64. 2007To summarize and critically appraise the available evidence on exercise therapy and other types of physical therapies for patients with neuromuscular diseases (NMD).
- Lung insufflation capacity in neuromuscular diseaseJohn Robert Bach
Department of Physical Medicine and Rehabilitation, University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark, New Jersey, USA
Am J Phys Med Rehabil 87:720-5. 2008....
- Intravenous immunoglobulin in the treatment of autoimmune neuromuscular diseases: present status and practical therapeutic guidelinesM C Dalakas
Neuromuscular Diseases Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Building 10, Room 4N248, 10 Center Drive MSC 1382, Bethesda, Maryland 20892 1382, USA
Muscle Nerve 22:1479-97. 1999..Finally, safety issues, risk factors, adverse reactions, spurious results or serological tests, and practical guidelines associated with the administration of IVIg in the treatment of neuromuscular disorders are presented...
- A framework for diagnosing and classifying intensive care unit-acquired weaknessRobert D Stevens
Division of Neurosciences Critical Care, Department of Anesthesiology Critical Care Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
Crit Care Med 37:S299-308. 2009..We propose a simple framework for diagnosing and classifying neuromuscular disorders acquired in critical illness...
- Classification of EMG signals using neuro-fuzzy system and diagnosis of neuromuscular diseasesSabri Koçer
Department of Electronic and Computer Education, Faculty of Technical Education, Gazi University, Ankara, Turkey
J Med Syst 34:321-9. 2010..Coefficients that were obtained from the EMG signals using Autoregressive (AR) analysis was applied to neuro-fuzzy system. The classification performance of the feature sets was investigated for three classes...
- Speech pathology interventions in patients with neuromuscular diseases: a systematic reviewS Knuijt
Research Centre for Allied Health Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
Folia Phoniatr Logop 63:15-20. 2011A systematic review was conducted to summarize and evaluate the literature on the effectiveness of speech pathology interventions in adults with neuromuscular diseases.
- Manual muscle strength testing of critically ill patients: feasibility and interobserver agreementCatherine L Hough
Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Washington, 325 Ninth Avenue, Mailstop 359762, Seattle, WA 98104, USA
Crit Care 15:R43. 2011..We studied the feasibility and interobserver agreement of this sum score in a mixed cohort of critically ill and injured patients...
- A review: the use of rituximab in neuromuscular diseasesHomam Ibrahim
The Methodist Hospital, Houston, TX, USA
J Clin Neuromuscul Dis 12:91-102. 2010..In this article, we review and discuss the available literature on rituximab in treatment of various autoimmune neuromuscular diseases.
- Axial myopathies: an elderly disorderG Serratrice
Faculte de Medecine, Méditerranée University of Marseille, France
Acta Myol 26:11-3. 2007
- The role of future longitudinal studies in ICU survivors: understanding determinants and pathophysiology of weakness and neuromuscular dysfunctionCatherine L Hough
Department of Medicine, University of Washington, Seattle, Washington, USA
Curr Opin Crit Care 13:489-96. 2007..The goals of this review are to discuss the pathophysiology and determinants of muscle weakness and neuromuscular dysfunction after critical illness, and to offer thoughts regarding the role of future longitudinal studies in this area...
- Neuromuscular dysfunction acquired in critical illness: a systematic reviewRobert D Stevens
Department of Anesthesiology Critical Care Medicine, Johns Hopkins University School of Medicine, 600 N Wolfe St, Meyer 8 140, Baltimore, MD 21287, USA
Intensive Care Med 33:1876-91. 2007..To determine the prevalence, risk factors, and outcomes of critical illness neuromuscular abnormalities (CINMA)...
- Impact of a home-based activity and dietary intervention in people with slowly progressive neuromuscular diseasesDavid D Kilmer
Department of Physical Medicine and Rehabilitation, University of California Davis Medical Center, Sacramento, CA 95817, USA
Arch Phys Med Rehabil 86:2150-6. 2005..To determine whether a home-based activity and dietary intervention can increase activity level, reduce caloric intake, and impact positively components of metabolic syndrome in a disabled population...
- Sleep disorders in neuromuscular diseasesUpinder K Dhand
Department of Neurology, Division of Pulmonary, Critical Care and Environmental Medicine, University of Missouri, Columbia, Missouri 65212, USA
Curr Opin Pulm Med 12:402-8. 2006..This paper reviews the mechanisms, diagnostic evaluation, and management of sleep disorders in various neuromuscular diseases.
- Novel mitochondrial transfer RNA(Phe) gene mutation associated with late-onset neuromuscular diseaseMarcus Deschauer
Department of Neurology, Martin Luther Universitat Halle Wittenberg, Halle Saale, Germany
Arch Neurol 63:902-5. 2006....
- Stem cell-mediated muscle regeneration and repair in aging and neuromuscular diseasesA Musaro
Department of Histology and Medical Embryology, CE BEMM and Interuniversity Institute of Myology, Sapienza University of Rome, Italy
Eur J Histochem 51:35-43. 2007....
- Electron microscopy in neuromuscular disordersCarla Fernandez
Department of Pathology and Neuropathology, Hopital de la Timone, Marseille, France
Ultrastruct Pathol 29:437-50. 2005..Moreover, electron microscopy gives insight on pathophysiological mechanisms and can guide molecular genetics analysis...
- 117th ENMC workshop: ventilatory support in congenital neuromuscular disorders -- congenital myopathies, congenital muscular dystrophies, congenital myotonic dystrophy and SMA (II) 4-6 April 2003, Naarden, The NetherlandsCarina Wallgren-Pettersson
The Folkhälsan Department of Medical Genetics, University of Helsinki, PO Box 211, Topeliuksenkatu 20, Fin 00251 Helsinki, Finland
Neuromuscul Disord 14:56-69. 2004
- Fatigue is part of the burden of neuromuscular diseasesJohn H J Wokke
J Neurol 254:948-9. 2007
- Intravenous immunoglobulin in autoimmune neuromuscular diseasesMarinos C Dalakas
Neuromuscular Diseases Section, National Institutes of Health, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892, USA
JAMA 291:2367-75. 2004..These mechanisms may explain the effectiveness of IVIG in autoimmune neuromuscular disorders...
- Persistent neuromuscular and neurophysiologic abnormalities in long-term survivors of prolonged critical illnessSimon N Fletcher
Intensive Care Unit and Department of Neurophysiology, St Bartholomew s Hospital, West Smithfield, London, UK
Crit Care Med 31:1012-6. 2003..To establish the prevalence, clinical characteristics, and electrophysiologic features of residual neuromuscular dysfunction after prolonged critical illness...
- Fatigue versus activity-dependent fatigability in patients with central or peripheral motor impairmentsBruce H Dobkin
Department of Neurology, University of California Los Angeles, Los Angeles, CA 90095, USA
Neurorehabil Neural Repair 22:105-10. 2008....
- Diagnostic immunohistochemistry in neuromuscular disordersD S Tews
Edinger Institute of the Johann Wolfgang Goethe University, Frankfurt, Germany
Histopathology 46:1-23. 2005..Nevertheless, as well as the diagnostic value of immunocytochemical analysis it may also widen understanding of muscle fibre pathology as well as help in the development of therapeutic strategies...
- [Arrhythmia follow-up of children and adolescents with neuromuscular diseases]Y Dulac
Cardiologie Pediatrique, Hôpital d Enfants, CHU Toulouse
Arch Mal Coeur Vaiss 100:490-5. 2007Much progress has been made over the last few years in understanding and classifying neuromuscular diseases. The heart is frequently affected but often in a dissociated manner with respect to the neuromuscular signs although it has a ..
- The use of intravenous immunoglobulin in the treatment of autoimmune neuromuscular diseases: evidence-based indications and safety profileMarinos C Dalakas
Neuromuscular Diseases Section, National Institute of Neurological Diseases and Stroke, National Institutes of Health, MSC 1382, Room 4N248, Building 10, 10 Center Drive, Bethesda, MD 20892 1382, USA
Pharmacol Ther 102:177-93. 2004..v.Ig with other immunosuppressive drugs...
- Prevalence of neuromuscular diseases in Chinese children: a study in southern ChinaBrian Chung
Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Pokfulam, China
J Child Neurol 18:217-9. 2003Our objective was to study the prevalence of neuromuscular diseases in Chinese children. A prospective study of neuromuscular diseases in Chinese children was conducted from 1985 to 2001 in Hong Kong, which is a city in southern China...
- Current concepts of respiratory complications of neuromuscular disease in childrenC M Schramm
Department of Pediatrics, University of Connecticut School of Medicine, Hartford 06106, USA
Curr Opin Pediatr 12:203-7. 2000Chronic neuromuscular diseases affect the respiratory muscles in varying patterns and degrees...
- Multilevel nerve compression and muscle imbalance in work-related neuromuscular disordersChristine B Novak
Division of Plastic and Reconstructive Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
Am J Ind Med 41:343-52. 2002..Work-related upper limb disorders have come under increasing scrutiny and become a frustrating problem...
- Early signs of critical illness polyneuropathy in ICU patients with systemic inflammatory response syndrome or sepsisA Tennilä
Department of Anaesthesia and Intensive Care, Helsinki University Hospital, Finland
Intensive Care Med 26:1360-3. 2000..To evaluate with electromyography the incidence and the time of appearance of neuromuscular abnormality in patients with systemic inflammatory response syndrome (SIRS) and/or sepsis...
- Nuclear envelope proteins and neuromuscular diseasesCecilia Ostlund
Department of Medicine, College of Physicians and Surgeons, Columbia University, 630 West 168th Street, Tenth Floor, New York, New York 10032, USA
Muscle Nerve 27:393-406. 2003Several neuromuscular diseases are caused by mutations in emerin and A-type lamins, proteins of the nuclear envelope. Emery-Dreifuss muscular dystrophy is caused by mutations in emerin (X-linked) or A-type lamins (autosomal dominant)...
- Assessing inspiratory muscle strength in patients with neurologic and neuromuscular diseases : comparative evaluation of two noninvasive techniquesI Iandelli
Fondazione Don C Gnocchi ONLUS, Section of Respiratory Rehabilitation, Pozzolatico, Firenze, Italy
Chest 119:1108-13. 2001..study was to assess whether mouth pressure during sniff maneuver (Pmosn) is a better index of inspiratory muscle strength than MIP in patients with neurologic and neuromuscular diseases (NNMD) with and without inspiratory muscle weakness.
- Hereditary neuromuscular diseasesO Ozsarlak
Department of Radiology, University Hospital Antwerp, Wilrijkstraat 10, B 2650 Edegem, Belgium
Eur J Radiol 40:184-97. 2001This article presents the actual classification of neuromuscular diseases based on present expansion of our knowledge and understanding due to genetic developments...
- Critical illness polyneuropathyWalther N K A van Mook
Department of Intensive Care, University Hospital Maastricht, Maastricht, The Netherlands
Curr Opin Crit Care 8:302-10. 2002..Knowledge of CIP is essential for intensivists and other specialists who care for critically ill patients. This review summarizes the current available literature on this topic...
- Immunohistological analyses of neutral glycosphingolipids and gangliosides in normal mouse skeletal muscle and in mice with neuromuscular diseasesM Cacic
Department of Chemistry and Biochemistry, School of Medicine, University of Zagreb, Croatia
Glycoconj J 12:721-8. 1995..gangliosides was investigated in cryosections of normal mouse skeletal muscle and in muscle of mice with neuromuscular diseases using indirect immunofluorescence microscopy...
- The neuromuscular basis of hereditary kyphoscoliosis in the mouseL R Bridges
Department of Histopathology, Charing Cross and Westminster Medical School, London, United Kingdom
Muscle Nerve 15:172-9. 1992..Peripheral nerves and anterior horn cells were normal. The findings indicate a neuromuscular basis of hereditary kyphoscoliosis in the mouse. The animal may be useful as a model of human muscle disease and scoliosis...
- The role of neurotrophins in muscle under physiological and pathological conditionsGuillaume Chevrel
Department of Neuroimmunology, Max Planck Institute of Neurobiology, Martinsried, Germany
Muscle Nerve 33:462-76. 2006..The goal of this review is to provide a basis for a better understanding and future studies on the role of these factors under such pathological conditions and for treatment of human muscle diseases...
- [Analysis of 14 individuals who requested predictive genetic testing for hereditary neuromuscular diseases]Kunihiro Yoshida
Division of Clinical and Molecular Genetics, Shinshu University Hospital, Third Department of Internal Medicine, Shinshu University School of Medicine
Rinsho Shinkeigaku 42:113-7. 2002Predictive genetic testing for hereditary neuromuscular diseases is a delicate issue for individuals at risk and their families, as well as for medical staff because these diseases are often late-onset and intractable...
- Role of physical activity and exercise training in neuromuscular diseasesWilliam M Fowler
Department of Physical Medicine and Rehabilitation, School of Medicine, University of California Davis, Davis, CA 95616, USA
Am J Phys Med Rehabil 81:S187-95. 2002..assessment of the state of the science regarding exercise training and fatigue in humans and animals with neuromuscular diseases. The conference comprised a nonfederal, nonadvocate, 20-member panel that brought together exercise ..
- Experienced and physiological fatigue in neuromuscular disordersM L Schillings
Department of Clinical Neurophysiology, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500 HB Nijmegen, The Netherlands
Clin Neurophysiol 118:292-300. 2007..It might be caused both by changes at the peripheral and at the central level. This study measured the level of experienced fatigue and physiological correlates of fatigue in three genetically defined neuromuscular disorders...
- Symptoms, clinical and physiological findings motivating home mechanical ventilation in patients with neuromuscular diseasesMichael Laub
Department of Respiratory Medicine, University Hospital, Lund, Sweden
J Rehabil Med 38:250-4. 2006To clarify the relationship between symptoms, clinical signs and physiological abnormalities that were motivating the initiation of home mechanical ventilation in patients suffering from neuromuscular diseases.
- Retrospective study of a large population of patients with asymptomatic or minimally symptomatic raised serum creatine kinase levelsAlessandro Prelle
Istituto di Clinica Neurologica, Ospedale Maggiore IRCCS, Milano, Italy
J Neurol 249:305-11. 2002..4% of patients, and to detect skeletal muscle abnormalities in 38.6% of the subjects. Interestingly, 31.6% of individuals had completely normal muscle findings. These best fit the "diagnosis" of idiopathic hyperCKemia...
- Accuracy of repetitive nerve stimulation for diagnosis of the cramp-fasciculation syndromeTaylor B Harrison
Department of Neurology, Emory University, 101 Woodruff Circle, Suite 6000, Room 6103, Atlanta, Georgia 30322, USA
Muscle Nerve 35:776-80. 2007..These results suggest that CFS represents a form of peripheral nerve hyperexcitability and, furthermore, that RNS is a clinically useful test for CFS...
- Quantitative skeletal muscle ultrasound: diagnostic value in childhood neuromuscular diseaseS Pillen
Department of Clinical Neurophysiology, Institute of Neurology, Neuromuscular Centre Nijmegen, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500 HB Nijmegen, The Netherlands
Neuromuscul Disord 17:509-16. 2007..Muscle thickness and quantitatively determined echo intensity of four muscles and the distribution of these variables within the body were examined...
- Diagnostic evaluation of clinically normal subjects with chronic hyperCKemiaC Fernandez
Laboratoire d Anatomie Pathologique et Neuropathologie, Hopital de la Timone Adultes, Marseille, France
Neurology 66:1585-7. 2006..The probability of making a diagnosis was higher in children and when creatine kinase level was greater than 2,000 UI/L...
- Sensitivity and specificity of qualitative muscle ultrasound in assessment of suspected neuromuscular disease in childhoodKnut Brockmann
Department of Pediatrics and Pediatric Neurology, Georg August University, Gottingen, Germany
Neuromuscul Disord 17:517-23. 2007..Accuracy of ultrasound was lower in younger children. High reliability of muscle sonography justifies a more widespread use of this method in evaluation of suspected NMD in childhood...
- The basics of electromyographyK R Mills
Department of Clinical Neurophysiology, King s College Hospital, Denmark Hill, London SE5 9RS, UK
J Neurol Neurosurg Psychiatry 76:ii32-5. 2005
- Correction of neuromuscular scoliosis in patients with preexisting respiratory failureInder Gill
Department of Orthopaedics, Freeman Hospital, Newcastle upon Tyne, U K
Spine (Phila Pa 1976) 31:2478-83. 2006..A prospective observational study in scoliosis patients who were on noninvasive night ventilation for respiratory failure...
- Quantitative motor unit action potential analysis of skeletal muscles in the Warmblood horseI D Wijnberg
Department of Equine Sciences, Utrecht University, The Netherlands
Equine Vet J 34:556-61. 2002..08 microV) in the subclavian muscle. The number of turns of the lateral vastus (3.0 +/- 1.22) was significantly higher than that of the triceps muscle (2.7 +/- 1.51). No differences were found in MUP duration (5.9-6.4 ms)...
- Skeletal muscle ultrasonography: Visual versus quantitative evaluationSigrid Pillen
Department of Clinical Neurophysiology, Institute of Neurology, Nijmegen, The Netherlands
Ultrasound Med Biol 32:1315-21. 2006..53). We conclude that quantification of echo intensity is a more objective and accurate method. Because it can achieve higher sensitivities, it is better-suited for the screening task in the diagnostic phase of children with a NMD...
- A new motor performance test in a prospective study on children with suspected myopathyWilleke A van den Beld
Interdisciplinary Child Neurology Centre and Department of Rehabilitation Medicine, University Medical Centre Nijmegen St Radboud, Nijmegen, The Netherlands
Dev Med Child Neurol 48:739-43. 2006..This non-invasive and child-friendly motor performance test can improve diagnostic procedure and, therefore, spare more children from unnecessary muscle biopsy...
- Classification of EMG signals using PCA and FFTNihal Fatma Güler
Department of Electronics and Computer Education, Faculty of Technical Education, Gazi University, Teknikokullar, Ankara, Turkey
J Med Syst 29:241-50. 2005..Consequently, the results show that SVM has high anticipation level in the diagnosis of neuromuscular disorders. It is proved that its test performance is high compared with MLP...
- Use of support vector machines and neural network in diagnosis of neuromuscular disordersNihal Fatma Güler
Department of Electronics and Computer Education, Faculty of Technical Education, Gazi University, Teknikokullar, Ankara, Turkey
J Med Syst 29:271-84. 2005..Besides, these coefficients were tested both in ANN and SVM. The results show that SVM has high anticipation level in the diagnosis of neuromuscular disorders. It is proved that its test performance is high compared with ANN...
- The risk of malignant hyperthermia in children undergoing muscle biopsy for suspected neuromuscular disorderRandall P Flick
Department of Anesthesiology, Mayo Clinic, Rochester, MN 55905, USA
Paediatr Anaesth 17:22-7. 2007..Despite the lack of conclusive data, most of these children are managed with a nontriggering anesthetic. This study examined the risk of MH in children exposed to a triggering anesthetic while undergoing muscle biopsy for suspected NMD...
- [Dystrophin detection by immunofluorescent technique for diagnosing muscular dystrophy]Xun Wang
Department of Neurology, First Affiliated Hospital, Sun Yat Sen University, Guangzhou, Guangdong, 510080 P R China
Zhonghua Yi Xue Yi Chuan Xue Za Zhi 19:239-42. 2002..To establish a specific technique for diagnosing and classifying Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), facioscapulohumeral muscular dystrophy (FSHD) and neurologic dystrophy...
- [Diagnosis and differential diagnosis of lysosomal glycogen storage disease]D Fischer
Neurologische Klinik und Poliklinik, Rheinische Friedrich Wilhelms Universitat Bonn
Nervenarzt 74:896-9. 2003..We discuss clinical and electrophysiological features of muscular lysosomal glycogenosis, with special emphasis on the histopathological differential diagnosis of the disease...
- Clinical applications of high-density surface EMG: a systematic reviewGea Drost
Department of Clinical Neurophysiology, Institute of Neurology, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500 HB, Nijmegen, The Netherlands
J Electromyogr Kinesiol 16:586-602. 2006..We additionally discuss several bioengineering aspects and future clinical applications of the technique and provide recommendations for further development and implementation of HD-sEMG as a clinical diagnostic tool...
- Nerve excitability testing and its clinical application to neuromuscular diseasesHiroyuki Nodera
Department of Neurology, Graduate School of Medicine, Tokushima University, 2 50 1 Kuramoto, Tokushima 770 8503, Japan
Clin Neurophysiol 117:1902-16. 2006..Here, we review the basics of ion channel functions and membrane properties that influence nerve excitability, the basic principles of nerve excitability testing and the reported findings in various disorders...
- [The predominance of myopathy as a cause of intensive-care-unit-acquired paralysis: the diagnostic value of direct muscle stimulation]T Nordine
Service de Physiologie, Explorations Fonctionnelles, Hopital Henri Mondor, Assistance Publique Hopitaux de Paris, Creteil
Rev Neurol (Paris) 163:181-7. 2007..In the intensive care unit (ICU) patients sometimes develop diffuse neuromuscular deficit resulting in flaccid tetraparesia with a more or less severe prognosis...
- Neuromuscular function in survivors of the acute respiratory distress syndromeMichael J Angel
Department of Medicine, Division of Neurology, University Health Network, University of Toronto, Toronto, Ontario, Canada
Can J Neurol Sci 34:427-32. 2007..Persistent neuromuscular complications of ARDS may contribute to the functional disability observed in these patients...
- [Recent progress in pediatric neurological rehabilitation]V Leroy-Malherbe
Médecin de rééducation, centre ressources pour l enfant avec lésion cérébrale acquise, Hopital National de Saint Maurice, 14, rue du Val d Osne, 94415 Saint Maurice, France
Arch Pediatr 9:70-7. 2002..Networking with the family and other actors in the environmental field is essential to achieve a better social integration. A true collaboration between physicians and pediatricians is necessary to work toward more progress...
- Advancing the role of electrodiagnostic techniques in equine neuromuscular diseaseSimon R Platt
Equine Vet J 34:538-9. 2002
- Neurological and neuromuscular disease as a risk factor for respiratory failure in children hospitalized with influenza infectionRon Keren
Division of General Pediatrics, Pediatric Generalist Research Group, Department of Medicine, The Children s Hospital of Philadelphia, PA 19104, USA
JAMA 294:2188-94. 2005..Little is known about the relative contribution of each of these chronic medical conditions to the development of serious influenza-associated complications...
- Muscle coenzyme Q: a potential test for mitochondrial activity and redox statusLili Miles
Division of Pathology and Laboratory Medicine, Cincinnati Children s Hospital Medical Center, Cincinnati, Ohio 45229, USA
Pediatr Neurol 32:318-24. 2005..This study suggests that total CoQ concentration provides a new method for estimating mitochondrial activity in biopsy muscle; and that the muscle CoQ test is feasible and potentially useful for diagnosing CoQ deficiency states...
- [Domiciliary assisted ventilation in children]C Schweitzer
Service d Explorations Fonctionnelles Pédiatriques, Hôpital d Enfants, CHU de Nancy, Allee du Morvan, 54500 Vandoeuvre les Nancy
Rev Pneumol Clin 58:139-44. 2002..Home ventilation, particularly with non-invasive assistance is a reliable method for long-term treatment of chronic alveolar hypoventilation in children. The appropriate time for initiating this therapy should be better defined...
- Peripheral neuropathy, episodic myoglobinuria, and respiratory failure in deficiency of the mitochondrial trifunctional proteinUte Spiekerkoetter
Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
Muscle Nerve 29:66-72. 2004..Therefore, this disorder must be considered in the differential diagnosis of progressive peripheral neuropathy with or without episodic myoglobinuria...
- Critical illness neuromuscular disease: clinical, electrophysiological, and prognostic aspectsB Tabarki
Service de neuropédiatrie et service de neurologie, Cliniques Universitaires Saint Luc, Universite Catholique de Louvain, Avenue Hippocrate 10, 1200 Brussels, Belgium
Arch Dis Child 86:103-7. 2002..Critical illness neuromuscular disease, which has been recognised as a distinct clinical entity in adults, remains poorly described in children...
Research Grants77
- NEUROMUSCULAR TARGETS OF BOTULINUM TOXINJULIE COFFIELD; Fiscal Year: 2002..Botulinum toxin is also used clinically to treat neuromuscular diseases characterized by hyperactivity...
- Ca Signaling in Progression of Amyotrophic Lateral Sclerosis in Skeletal MuscleJingsong Zhou; Fiscal Year: 2010..We anticipate that information obtained from our research will apply to other neuromuscular diseases, such as aging, diabetes, Parkinson's disease and others, where altered Ca signaling and ..
- ANESTHETIC REACTIONS IN SURGERYCharles Louis; Fiscal Year: 1999..protein complexes that effect Ca2+ regulation in muscle and neurons; and will be important in the future elucidation of the etiology of other neuromuscular diseases in which excitation-contraction coupling or Ca2+ regulation is abnormal.
- Electrical Impedance Myography In Focal Neurological DiseaseAndrew Tarulli; Fiscal Year: 2007..We are developing electrical impedance myography as a painless, noninvasive, quantifiable technique to assess focal neuropathies of the hand, and neuromuscular diseases in general.
- PHYSIOLOGIC BASIS OF MUSCLE FUNCTIONAL MRIRONALD MEYER; Fiscal Year: 2005..functional magnetic resonance imaging (FMRI) methods for diagnosis and monitoring the progression of neuromuscular diseases and other fatigue syndromes...
- MOLECULAR PHYSIOLOGY OF NEUROMUSCULAR DISEASESStephen Cannon; Fiscal Year: 2002..are designed to provide a more complete understanding of the pathophysiologic basis for a group of human neuromuscular diseases: from gene defect to clinical symptoms...
- Magnetic Resonance Imaging and Biomarkers for Muscular DystrophyKRISTA H VANDENBORNE; Fiscal Year: 2010..DMD is one of the most devastating genetically linked neuromuscular diseases and is characterized by the absence of dystrophin, resulting in progressive muscle weakness, loss of ..
- Mechanisms underlying myostatin regulation and activitySe Jin Lee; Fiscal Year: 2010..in disease states characterized by debilitating muscle loss, including muscle degenerative diseases, neuromuscular diseases, cachexia, and age-related sarcopenia...
- RNA Binding Proteins & Alternative SplicingPaula Grabowski; Fiscal Year: 2007..Abnormalities in alternative splicing are associated with neurodegenerative, psychiatric and neuromuscular diseases, as well as various cancers...
- Biophysical studies of human choline transporters linked to cholinergic synapsesHideki Iwamoto; Fiscal Year: 2007..contribute to Alzheimer's disease and schizophrenia, and diminished cholinergic signaling correlates with neuromuscular diseases, such as myasthenia and tardive dyskinetics...
- PRESYNAPTIC MECHANISMS IN HAIR CELLSWilliam Roberts; Fiscal Year: 2002..and disorders of specific neurotransmitter systems underlie a number of psychiatric, neurological, and neuromuscular diseases. A better understanding of synaptic transmission will thus advance human health...
- NEUROMUSCULAR TARGETS OF BOTULINUM TOXINJULIE COFFIELD; Fiscal Year: 2006..Ironically, botulinum toxin is also a valued drug used to treat neuromuscular diseases characterized by muscle spasticity...
- A New Family of Voltage-gated Potassium Channel Regulaory SubunitsSteve Goldstein; Fiscal Year: 2007..in accessory subunits and regulatory motifs have been seen to cause life- threatening cardiac arrhythmias, neuromuscular diseases like epilepsy and periodic paralysis...
- Mitochondiral Injury and Anemia in Elderly Patients with Chornic Kidney DiseaseMadhumathi Rao; Fiscal Year: 2007..Mitochondrial DNA mutations have been reported in a variety of inherited neuromuscular diseases, diabetes, atherosclerosis, and age-related neurodegenerative disease...
- Bulbar Motor Deterioration in ALSYana Yunusova; Fiscal Year: 2010..PUBLIC HEALTH RELEVANCE: ALS, or Lou Gehrig's disease, is one of the most common and devastating neuromuscular diseases worldwide, affecting both women and men of all races and ethnic backgrounds...


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A collection of news and information related to The Wall Street Journal published by this site and its partners.
Top The Wall Street Journal Articles
Displaying items 49-60
Can the GOP reverse the damage done by Iraq?
Government workers deserve no sympathyStory | Dec 10, 2012 | 12:00 PMAs a taxpayer and a private-sector employee all my life, why should I feel sorry for the federal employees who, on average, make more money than me, have a better pension than I do, have more vacation time to be with their families, and work fewer hours...
Is this Cyber Monday the last without sales tax?
Terrence Cody: Does this Ravens jersey make me look fat?
Terrence Cody, Mike Golic and the new Nike uniforms
Romney and the doomsayers
Fire department invites you to give blood and attend a quarter auction[Elkridge]Story | Jun 19, 2013 | 6:10 PMThe Elkridge Volunteer Fire Department will hold a blood drive on Thursday, June 27, 3 to 8 p.m., in the fire hall at 6275 Old Washington Road. According to the American Red Cross, 60 percent of the U.S. population is eligible to donate; however, only...
Mildred Kern, U.N. worker
Wes Moore: Why I came back to Baltimore
Looks like Uber, an app for hiring private car drivers, wants to come to BaltimoreStory | Oct 17, 2012 | 2:28 PMUber, the popular car-hire service that's been making waves (and controversy) across the U.S., is interested in setting up shop in Baltimore, according to its website and to a job description on Jobvite for an operations manager. (H/T to...
Letter: DREAM Act a nightmare for U.S. students, workersStory | Oct 18, 2012 | 9:11 AMMarylanders will soon vote on question 4, the DREAM Act. According to Calvin Ball's Oct. 11 column, we should vote "yes" on 4 because "all students (should) have access to the education they need." I agree, Mr. Ball. But first, let us look at who won't...
Harborplace sold to New York real estate firm

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So comfortable and cute!
I just got these yesterday and couldn't wait to wear them today. I got them in Scarlet which is more of a country red, not a bright red. These shoes couldn't be more comfortable and cute. My feet are rather wide and yet, they do not feel squished, squeezed or bothered by anything. I love the feel of the little bumps on my soles and I love the wedge. I feel so stable wearing them, even though the heel is pretty high. I know I'll be wearing them a lot this summer!
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Love it!
They are the most comfortable sandal/heels ever! I normally wear a 7 or 7.5, depending on the width of the toe box and bought a 7 which fits me perfectly. My toes are a bit wide, but my heels are narrow, so the sling is perfect for my foot shape. The front is on the wider side of average, so people with narrow feet may slide through. The cushioning from the Croc sole is AMAZING. I stand most of my day at work and didn't have any discomfort after 9 hours! Usually with any heels, even low ones, the ball of my foot becomes very sore and achy, but not with these! I had given up wearing anything with a heel (except for very short periods of time), but not now! The leather was comfy, no break in needed at all. I have several pair of comfort D****o shoes and these are as comfortable or more for a fraction of the price! Would love to see this sole on many other styles (closed toe, dressier, ankle strap, etc. I'll be wearing them until the weather turns cold! Love them!
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All the Crocs comfort... With STYLE! People are amazed to find out that they are Crocs. Note that the back strap does slip occasionally, but this was easily remedied by tightening the strap. A cobbler can add holes for you if it's a problem. IMO, the benefits DEFINITELY outweigh this challenge! Love these shoes!
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BEST shoe
This was by far my favorite pair of shoes I have ever bought. I have spent allot of money on shoes . This was not my most expensive wedge, but it was my favorite, I have traveled extensively and they were always my must take pair of shoes for comfort. I get compliments all the time on these and I admit most people are shocked to find out that they are crocs. They look allot more expensive than they are. My only regret is leaving them out, puppy got to them and chewed them up. Gotta buy another pair. They are extremely durable otherwise.
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Home > Post > Post 1 > Post 1 News Release > 2013 News Releases > News Release
News Release
KSP working shooting in Carlisle County
Date of News Release: 10/03/2013
(Arlington, Ky.) The Kentucky State Police received a call on Thursday October 3, 2013 at approximately 01:46 A.M. in reference to a shooting and stabbing that had just occurred in Carlisle County.
Two white males, armed with a handgun and knife, entered a residence wearing ski masks and demanded money and property from the homeowner, Edward L. Wallace, 36 of Arlington. Mr. Wallace attempted to disarm one of the males and was stabbed multiple times and was shot once. The two males then fled the residence in an unknown direction of travel.
Mr. Wallace was transported to Jackson Purchase ER in Mayfield, KY and was later transferred by ambulance to Vanderbilt, Hospital in Nashville, TN for his injuries.
During the investigation KSP located and recovered 4.7 grams of methamphetamine and marijuana from Mr. Wallace's property. KSP believes this attempted robbery was an isolated incident.
The investigation continues by Detective Kyle Nall. Anyone with information may contact the Kentucky State Police at 270-856-3721 or toll-free in Kentucky, at 1-800-222-5555, callers may remain anonymous. The public can also text-a-tip at 67283 and remain anonymous.
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The Driver Behind Microsoft's (MSFT) 6% Surge
NEW YORK (TheStreet) -- Microsoft (MSFT) led the S&P 500 into all-time-high territory on Friday after it beat analyst expectations on earnings. Shares were surging 6.4% to $35.88 in afternoon trading. The S&P was gained 0.3% to 1,756.82 to extend its 2013 advance to 24%.
Seattle-based Microsoft reported first-quarter earnings of 62 cents a share, over 53 cents a share in the year-ago quarter. Revenue was 16% higher to $18.53 billion.
Analysts surveyed by Thomson Reuters had anticipated earnings of 54 cents a share on $17.79 billion in revenue. Expectations for the quarter had been conservative as investors dealt with uncertainty over management's succession plan and an expensive acquisition of Nokia's mobile arm.
The main source of growth, Microsoft's commercial segment -- which houses Office software licenses and enterprise-level sales -- posted a 10% year-on-year revenue increase to total $11.2 billion. Within the segment, commercial cloud revenue grew 103%. The Devices and Consumer segment grew 4% to $7.46 billion."We saw strong focus across our teams, generating record first-quarter revenue even as we navigate a fundamental business transition. Our enterprise renewals were very healthy and our devices and consumer business continued to improve," said CFO Amy Hood in a statement. For the second quarter, the company anticipates revenue between $23.1 billion to $24.1 billion, more than analysts' prediction of $22.9 billion. In the Devices and Consumer segment, management expects revenue of $5.2 billion to $5.4 billion. Hardware sales are expected to climb 35% to 45%, boosted by the expanded Surface line and Xbox One launch. For Commercial, Microsoft predicts revenue of between $10.7 billion to $10.9 billion, representing 9% to 11% in year-on-year growth. "As we look forward to the second quarter, our enterprise business will remain strong and we are also set up for a fantastic holiday season with Surface, Xbox One and a host of devices from our partners, which will allow us to reach new customers and drive increased engagement," said Hood during a conference call. TheStreet Ratings team rates Microsoft Corp as a Buy with a ratings score of A-. The team has this to say about their recommendation: "We rate Microsoft Corp (MSFT) a BUY. This is based on the convergence of positive investment measures, which should help this stock outperform the majority of stocks that we rate. The company's strengths can be seen in multiple areas, such as its revenue growth, largely solid financial position with reasonable debt levels by most measures, notable return on equity, attractive valuation levels and increase in stock price during the past year. We feel these strengths outweigh the fact that the company shows weak operating cash flow."
- You can view the full analysis from the report here: MSFT Ratings Report
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WKC Forum: Innovation for Ageing Populations – Enhancing adherence: medication and nutrition
1 October 2014
In commemoration of the UN International Day of Older Persons celebrated every year on 1 October, the WHO Kobe Centre will organize an open forum on "Innovation for Ageing Populations – Enhancing adherence: medication and nutrition" in Kobe.
A patient's therapeutic behaviours used to be judged passively based on the concept of "compliance" – how closely a patient follows the treatment prescribed by a doctor. Today, more important to supporting treatment success depends on the extent to which a person's behaviour – taking medication, following a diet, and/or executing lifestyle changes – corresponds with agreed recommendations from a health care provider. This is the concept of "adherence". Adherence to therapies is a primary determinant of treatment success.
In this forum, Japanese experts in the field of gerontology, medication, and nutrition, will present their work to enhance adherence which can contribute to healthy ageing.
Previous forums
WKC Forum: Innovation for Ageing Populations – Addressing the challenges of frailty and disability –
24 June 2014
WKC Forum: Innovation for Healthy Ageing
– Examples of current trends in research –
5 March 2014
WKC Forum:
Suicide Prevention and Community Support
19 December 2013
WKC Forum "Control your blood pressure: for your healthy life" in commemoration of the World Health Day
7 April 2013
World Health Day 2013
Invitation to WKC forum, 7 April 2013
7 April 2013
WKC Forum
International Health Emergencies
18 January 2013
"Stop tobacco industry interference"
– WHO Kobe Centre marked World No Tobacco Day with an open forum
31 May 2012
World No Tobacco Day 2012
– Stop tobacco industry interference
Invitation to WKC forum, 31 May 2012
31 May 2012
World Health Day 2012 – Ageing and Health
Invitation to WKC forum, 7 April 2012
7 April 2012
WKC Forum on Kaigo yobo interventions: the state of the art and future challenges in Japan
21 March 2012
Living a culture of disaster resilience at all levels
20 November 2011
The challenge to protect the health of 1.6 billion people
27 May 2011
Depression nearly tripled in Japan over last decade
WKC public health forum
4 March 2011
Japan the oldest society in history: forum
WKC public health forum
2 February 2011
Smoke-free champion shares story on 50% reduction of street smoking in Shizuoka
WKC public seminar
15 January 2011


text:
Book Review
Genre: Series
2006 Harlequin Intrigue Nominee
Lost in a Colorado blizzard, geologist Shana Parisi is rescued by soldier Luke Rawlins and taken to a nearby mountain cabin -- and the year is 1945. Met with suspicion by the Army and with no identification, Shana finds herself working with scientist Enrico Fermi on the Manhattan Project as she helps Luke battle Russian spies intent on killing them. And though trying to get back to her own time, Shana finds her feelings for Luke make her consider remaining in the past. Cassie Miles takes a stellar turn at a time-travel tale of intrigue and romance in the evocative Footprints in the Snow (4.5).
Reviewed By: Pat Cooper
Publisher: Harlequin
Published: October 2006


text:
Lifelong learning programs at Bradley began in 1994 with the Institute for Learning in Retirement (ILR).
In 2008, The Bernard Osher Foundation awarded Bradley a grant that established the Osher Lifelong Learning Institute–OLLI at Bradley University.
A subsequent gift from the Foundation endowed OLLI thus ensuring its long term viability while recognizing it as a program of national distinction.
For a more detailed history from 1994 to 2004, view our 10th Anniversary Booklet.


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This month, we'll hear summaries of three great business books:
Team Turnarounds by Daniel Leidl and Joe Frontiera.
Adaptability by Max McKeown.
Winning with Transglobal Leadership by Nazneen Razi, Ph.D., Peter Barge, Robert A. Cooke, Ph.D., Linda D. Sharkey, Ph.D.
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New U.S. Military CD Geiger Counter Charger and 2 Dosimeters
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MMA News
Wednesday, 08/01/2012, 06:36 pm
Eddie Bravo Addresses Royler Gracie's Comments, Says "He talked a lot of ****…"
An uncensored Eddie Bravo responds to Royler Gracie's rematch challenge, Joe Rogan getting his black belt, and gives an explanation as to why negotiations for the Royler rematch previously fell through. Royler's interview can be viewed HERE.
Latest News


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Georgia Power officials say a system of severe thunderstorms has left about 65,000 customers without power.
Severe thunderstorm warnings were in effect throughout much of north and middle Georgia Thursday evening as the storm dumped heavy rain and lit up the night sky with lightning. Severe thunderstorm warnings were expected to expire early Friday morning.
There were multiple reports of downed trees throughout north Georgia. Georgia Power officials said about 65,000 customers lost power as of 4:30 a.m.
National Weather Service forecasters say falling trees left two people with non-life threatening injuries in Canton, and the agency would likely send officials to Cherokee County Friday to determine if a tornado touched down there.
Meteorologists have said it looked like the storm was capable of producing a twister near Holly Springs.
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SALEM, Ohio- Graffiti has become such a problem in the City of Salem that council has even considered punishing property owners who don't remove it. Now, one group is working to resolve the issue, using a more positive approach.
More than 80 spots in Salem have been vandalized with graffiti. It's a problem Councilman Rick Drummond said is deterring potential businesses from settling in the area.
"I think for the most part people are disappointed that it's there, that their city has kind of slid to the point where it's on the walls and it's not coming off quickly," said Drummond.
The councilman says other cities have passed an ordinance, punishing property owners if the vandalism isn't cleaned-up. The idea was considered in Salem, but met with criticism as residents said, you're basically punishing the victim.
"If you can do it like we're hoping to do it, where the public gets involved, the main point is just to get rid of it quickly and consistently," Drummond said.
To help resolve the issue about a dozen residents have formed a task group. They hope to work with police to report and identify reoccurring markings, work with the schools to educate kids on the harm graffiti can have to community, as well as help victims of the vandalism clean-up.
"If one person does one thing, it just makes the problem so much smaller," said Owner of Salem Fun Factory, Lisa Cartwright.
Without funding from the city, the group hopes donations will help fund their effort. They've discussed offering rewards as an incentive to report suspected vandals and they've requested the courts punish to the full extent of the law.
"So it sets a record for people in the courts to see, if you do this, this is what's going to happen to you as a deterrent," said Councilwoman Cindy Baronzzi Dickey.
The group will hold another public meeting on Tuesday, February 26th at 6:00p.m. at City Council Chambers.
In the meantime, to report graffiti, Salem residents can call their ward representative or e-mail firstname.lastname@example.com


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The National Institutes of Health / National Institute on Drug Abuse (NIH/NIDA) Summer Internship Program in Biomedical Research offers hands-on experience and a unique opportunity for high school, college, graduate and medical students to develop skills in scientific research. Summer internships generally last from eight to ten weeks, beginning in June and ending in August. Some flexibility exists to accommodate individual student needs.
To be eligible for this program, students must be:
- A U.S. citizen or permanent resident;
- At least 16 years of age; and
- Enrolled at least half-time in an accredited U.S. high school, college or university.
Students must apply for the program electronically at the NIH Training Web site, https://www.training.nih.gov/programs/sip. The online application is available starting around Nov. 15. The application deadline is March 1.
You can learn about NIDA and the research conducted by our investigators at http://irp.drugabuse.gov. You can contact one of the investigators directly if you would like to intern with them.
Note: On the application, there is an item that asks for your institute preference. Select NIDA. After submitting your application, please send an e-mail to the NIDA Office of Education and Career Development (firstname.lastname@example.com) to let us know you have applied to the NIDA Summer Program.
If you have any questions about the Summer Internship Program or the application process, please feel free to contact us via the information below.
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In 2013, Andy Warstar released the second WARSTARS album of the year (strange, considering Warstars hadn't played together since 2010). And although the title of the album is not on the album cover, it appears in the name of this blog entry: NEVER MINED, i.e. 27 cover songs that were 'Never Mined' and whored out for profit! This Nirvana covers compilation was a long time comin'. Andy Warstar had been playing around with the idea for years because Warstars had jammed on so many Nirvana tunes over the years.
But why did this compilation take so long to be released? Well, take a look around. You won't see very many punk bands doing something so reprehensible as releasing a covers album of tunes by a completely sold-out wanna-be punk rock band like Nirvana. So the concern was that putting this album out while WARSTARS was still actively playing out might cause them the lose fans. Time heals all wounds however, and sometimes you've got to gash those wounds back open by releasing an album that will really irritate the purist punks. The people who aren't irritated by these songs? They're called 'Warheads'.
Never Mined kicks off with the very first Nirvana cover that Warstars ever attempted back in 2001, "Smells Like Warstars". It's obvious that the band wasn't trying very hard. The bass player's mom forced the band to let his 15 year old brother Chris sing on the song, and 'Teen Spirit' was the song Chris wanted to sing. So it's pretty funny shit right here. The album winds it's way on toward more serious attempts at Nirvana songs, like 'In Bloom' and a killer bootleg version of 'Love Buzz -> Attached 2 You' (the latter half of the song being a Warstars original).
A lot could be said about the other songs, including the 2 piece live version of 'Son Of A Gun', which was a feat in and of itself because that Warstars gig almost didn't happen, nor had the drummer ever played that song before! But in keeping with "saving the best for last", there's a very very nice version of Do Re Mi, a rare Kurt Cobain song that Andy Warstar does almost better than the original, and with a true to form Cobain style whine that would make any Nirvana fan proud (and glad somebody took the time to honor Kurt's singing/songwriting).
The last track on the album, 'Justice For Kurt', is a studio track produced in 2002. This song had to be the last nail in the coffin, as it was Andy Warstar's way of getting closure on Kurt's death. After all, WARSTARS is from the Northwest, and Andy Warstar had seen many of the so-called "grunge" bands of the nineties (as well as Nirvana at the No On 9 benefit in Portland, Oregon) back in his high school days. So this whole album is really a rather personal effort on the part of Andy Warstar. And Never Mined finally saw it's release in 2013 because Andy Warstar stopped caring about maintaining 'punk credibility' and just decided to do whatever the heck he wanted. Enjoy & Rock On...
Listen and download "Never Mined" by Andy Warstar & the Warstars for FREE here:
Download "Never Mined" by Andy Warstar & the Warstars HERE!
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He stands before the adoring crowd,
Basking in their cheers and standing ovation.
But he has already been dishonoured -
By means of his perverse innovation.
For none could know of the dark secret;
About the art that he claims to be his own.
It is naught but an illusion, smoke and mirrors -
A theft for which he must atone...
But this disgusting creature, this worthless abhuman;
So desperate for the glory which he sees upon the stage!
Will quietly don the skin of another;
An urge he must assuage...
Biting his nails, a cracked smile upon his lips, he whispers:
"No one will know, no one will find it and I am great..."
Coward of a ManCoward of a Man:
You stand there whinin', cryin' crocodile tears and playin' victim.
Ye eyes demand pity, but yer lips are spewin' nothin' but lies.
Flowery speeches o' harmony and unification;
It's bollocks and snake-oil I say!
I ask ye, as someone who aspires t' be a leader:
What exactly are ye worth?
Who exactly are ya, and what in th' bloody hell makes you worth followin'?
Now I've watched ye fer a long time, and I've known ye fer even longer -
Ye always stand there beggin', askin' us fer help, askin' fer a handout;
But yer hands are clean, uncalloused, and completely free from sweat or toil.
Instead, ye make us promises; promi
Little Soldier BoyHe does not fight for the General barking orders,
Nor for the man in a suit, who sent him across borders...
In his pocket he keeps a single picture, a sole reminder
Like ancient scripture. A home he misses so endlessly,
Tirelessly calling out in his dreams at night. It is the last
That remains on his lips, with his finger pressed upon the trigger.
A single heartbeat, as he sights his enemy; A quiet prayer
To rest in peace. Yet soon it fades, as hope is fleeting;
For the little soldier boy, once marching home.
"Bottoms up buddy, I miss you..."
-Chen Yuan Wen, 18th October 2012
I Comfort MyselfWith a warm drink, whispering secrets to my own reflection.
The struggles that plague me, though none may know,
Are only for the ears of my quiet mirror, who smiles
Softly, warmly and with care. He tells me, I'm fine
I've done well for now and soon I may finally rest.
Though the silence continues to press upon me,
Weighing upon my soul like an iron crate.
Still I find comfort in whispering secrets,
If only to my own reflection - holding a warm drink...
-Chen Yuan Wen, 17th October 2012
Mercenary 1-1MERCENARY
Chapter 1: Blood is Beauty
Release One: Pages 1 - 3
THE COLD AIR in Baron Rorke's study did little to calm his nerves. He was expecting visitors this night and they were not the best of company. A shiver of dread ran down his spine and he spent most of the twilight hours staring out of a large window which stood behind his writing desk. It was amazing, he felt, how quickly a man could become attached to a life of luxury; only to be made painfully aware of how easy it was to lose it. War was always a frightening thing, even more so when one had the knowledge and sense to realise that it was no longer an exercise of glory, but a si


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Cigarette smoking is a leading cause of preventable death worldwide and is associated with approximately 440,000 deaths in the United States each year, according to the U.S. Centers for Disease Control and Prevention, but nearly 20 percent of the U.S. population continues to smoke cigarettes. While more than half of U.S. smokers try to quit every year, fewer than 10 percent are able to remain smoke-free. Relapse commonly occurs within 48 hours of smoking cessation. However, learning about withdrawal and the difficulty of quitting can lead to more effective treatments to help smokers quit.
About Us
For over a decade, ThirdAge has been a leading source of information for "boomer and beyond" women. Our writers cover what means most to women 50+: the empty nest, living solo, finding love, coping with caregiving, and remaking their lives the way they want them to be. We also feature the latest approaches to brain fitness, diet, exercise, and age-related health conditions.


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Bing Falls for the First Time Since Launch
Microsoft's Bing has seen slow but steady month over month growth since it launched this past summer. However, September saw Bing's share of the U.S. search market fall to 8.5 percent.
New numbers from StatCounter show that rather than continuing its trend of acquiring more market share at the expense of competitors Google and Yahoo!, Bing fell by 1.1 percent (bringing the decision making engine down from 9.64 percent to 8.51 percent) while Google rose two full percentage points, moving to 80.08 percent, up from the 77.83 percent it had in August. Yahoo! also declined, moving to 9.40 percent from 10.50 percent.
This is rough news in itself, however the fact that its Bing's first decline since it launched in May.
"The trend has been downwards for Bing since mid August," commented Aodhan Cullen, CEO, StatCounter. "The wheels haven't fallen off but the underlying trend must be a little worrying for Microsoft."
Read more from StatCounter.
Create a new thread in the UK News comments forum about this subject
0skalagon , 5 October 2009 00:29Tried bing once, I remember it gave me results that had nothing to do with what I wanted, then tried google, first result was exactly what I was looking for.


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Results 1 to 7 of 7
I dont usually do forums, but saw a question, which I just felt compelled to answer having been down that road. I've been doing linux since the first Slackware release, ...
Enjoy an ad free experience by logging in. Not a member yet? Register.
- 10-10-2012 #1
- Join Date
- Oct 2012
- Posts
- 1
Intro for @Aj2
I've been doing linux since the first Slackware release, and have managed servers running various dist's since.
Currently its Debian for me.
Nice to meet you all.
- 10-10-2012 #2
Hello and Welcome, we're glad to have you join us here.I do not respond to private messages asking for Linux help, Please keep it on the forums only.
All new users please read this.** Forum FAQS. ** Adopt an unanswered post.
I'd rather be lost at the lake than found at home.
- 10-10-2012 #3
Welcome aboard!
Stick around. We got a pretty nice group here.Jay
New users, read this first.
New Member FAQ
Registered Linux User #463940
I do not respond to private messages asking for Linux help. Please keep it on the public boards.
- 10-10-2012 #4
- Join Date
- Oct 2012
- Posts
- 1
- 10-10-2012 #5
Welcome to the forum. Glad to have you join us.Registered Linux user #526930
- 10-10-2012 #6What do we want?
Time machines!
When do we want 'em?
Doesn't really matter does it!?
The Fifth Continent
- 10-10-2012 #7
- Join Date
- May 2004
- Location
- arch linux
- Posts
- 18,733
Hello and welcome to the forums... we're glad you've joined us!oz


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There are four methods by which the Bureau of Code Compliance receives violation notices. We encourage constituent involvement as we do our part to ensure a better, safer City of Atlanta. Below are the acceptable methods for submitting a code violation.
Phone—Contact the Bureau of Code Compliance at 404.330.6190, Monday through Friday between the hours of 8:15 am and 5:00 pm. to speak with a customer service representative. After normal business hours, all phone calls will be routed to our voice message system.
Print and Fax—Print this form and fax it to our office at 404.658.7084.
Area Survey—During an inspection of a specific property, Code Enforcement Officers may also conduct an area survey for additional code violations that exist on adjacent properties.
Email/Web Submission—Complete this form to submit a code violation request or send an inquiry to the Bureau of Code Compliance at email@example.com.
What happens once I submit my code compliance violation notice?..Click here
What are some types of Code Violations?
Contact Info
Office of Code Compliance
55 Trinity Avenue
Suite 3450
Atlanta, Georgia 30303
Customer Service Line
Major James Shaw
Tel: 404.330.6131
Fax: 404.546.8266
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School Briefs – Varina High School
Student Government Association hosted its second annual Blue Devil Dash 5k in October. Among the hundreds of runners who participated, Troy Hartle, a resident of King William County, won first place with a time of 19:11, and senior cross-country runner Carneal Waddey, won second place.
Carneal is a middle distance and distance runner for the cross-country team. This is his first year participating in the Blue Devil Dash. He said his senior year was a good year to participate in everything he possibly could. Because running is one of his favorite things to do, the dash was the perfect opportunity. His goal was to come in first place because he wanted to show other people how good he and his team really are.
"My goal was to win and get under 21 minutes," Carneal said.
Although Carneal won second place with a time of 19:36, he was disappointed. He had thought a first place finish was possible because he runs the same route every day to train for his cross-country races. Senior cross-country runner Kathleen Wilcox said she is proud of Carneal for representing the team and finishing in the top three.
"Even if he thought that he didn't do well, I'm personally very proud of him because he still finished in the top three and that's very good," Kathleen said.
Glen Allen student to perform at Carnegie Hall
Thanks to a first-place win in The American Protege International Vocal Competition 2014, Glen Allen High School student Matija Tomas will travel to New York City to perform at Carnegie Hall in December.
At the first-place winners recital in Weill Hall, Matija will perform Giacomo Puccini's opera aria, "Chi il bel sogna di doretta." She will perform with other vocalists from around the world and have the opportunity to win other awards and scholarships.
Locally, Thomas has performed with Richmond's renowned Glorious Christmas Nights, Christian Youth Theatre, and WEAG's Urban Gospel Youth Choir. > Read more.
Gayton Baptist Church dedicates new outreach center
The John Rolfe YMCA and Gayton Baptist Church have partnered in an effort to bring greater health and wellness opportunities to the community.
Through this partnership, the John Rolfe Y will run Youth Winter Sports programs, including basketball and indoor soccer, in Gayton's newly renovated $5.5 million outreach center that features a new gymnasium, youth and teen space, social space with café, meeting space and full service commercial kitchen. > Read more.
Henricus Historical Park to host Publick Day Sept. 20
Citizen Staff Reports 09/15/2014
Henricus Historical Park will commemorate its anniversary during Publick Day, a signature annual event that celebrates the establishment of the second successful English settlement in the New World. In September 1611, Sir Thomas Dale, along with soldiers, tradesmen and farmers, ventured from Jamestown to create the Citie of Henricus. Leaders of Henricus developed the first English hospital, chartered the first college in North America, established tobacco as the first cash crop in Virginia, and created a place where Pocahontas lived and met John Rolfe.
Publick Day will take place Saturday, Sept. 20, from 10 a.m. to 5 p.m. Admission is free and parking is $5 per vehicle. > Read more.
Page 1 of 117 pages 1 2 3 > Last ›
Extras sought for AMC's 'TURN'
Paid extras are being sought to appear in the AMC television series TURN: Washington's Spies, which will begin filming its second season in the Richmond area at the end of September and continue through February.
No experience is required, but producers say that extras must have flexible availability, reliable transportation and a positive attitude.
Arvold Casting is holding an open call on Sunday, Sept. 21 and is seeking men, women and children who are Caucasian, African American and Native American, with thin to average builds and who can realistically portray people living in Revolutionary War times. Long hair is a plus but not a must. > Read more.
Weekend Top 10
TGIF! Celebrate the weekend at Oak Hall Baptist Church's Community Block Party on Saturday. Learn more about ballroom dancing, art and Colonial times. Or take the kids to Generation Z Games for water play or Southern Season to cook up a Disney-theme meal. For all our top picks this weekend, click here! > Read more.
Weekend Top 10
Check out these three B's in Henrico this weekend: books, bluegrass and "Born Yesterday." Other activities to participate in – and feel good about – are the 15th annual James River Regional Cleanup and the 5th annual Richmond Out of the Darkness Community Walk. For all our top picks this weekend, click here! > Read more.
Business in brief
NBC News' Sara James to speak at Tucker HS convocation
Highland Springs HS wins Keep Virginia Beautiful grant
Henrico Police investigating suspicious death
Accreditation woes for HCPS
- More News
Print Edition
Sep. 18, 2014Click here to read the print edition.
Extras sought for AMC's 'TURN'
Weekend Top 10
Weekend Top 10
When the cliche stands tall
Weekend Top 10
- More Entertainment
Obituary – Susie Ann Walker
Obituary – Philip "Al" Cebulski
Obituary – Cecelia Davis Stevens
- More Obituaries
Glen Allen student to perform at Carnegie Hall
Gayton Baptist Church dedicates new outreach center
Henricus Historical Park to host Publick Day Sept. 20
- More Community
The Citizen at 13
Peeling off the labels
A messy food fight
- More Opinions
Hermitage to host Monday night football events
Down to the wire
Babe Ruth 13U World Series arrives in Glen Allen
- More Sports
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ClassifiedsSAVE on Cable TV-Internet-Digital Phone. Packages start at $89.99/mo (for 12 months.) Options from ALL major service providers. Call Acceller today to learn more! CALL 1-888-686-5081.
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CalendarThe Henrico Theatre Company will present "Born Yesterday," a classic comedy by Garson Kanin, Sept. 12-28 at The Cultural Arts Center at Glen Allen, 2880 Mountain Rd. Evening performances begin… Full text


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Lubbock County Justice of the Peace Aurora Hernandez and her husband City Councilman Victor Hernandez sued a multinational corporation and lost. A federal judge ruled in favor of Bank of America and against the Hernandez family on Tuesday.
Back in April, Mr. Hernandez sued on behalf of his wife in State District Court, asking a judge to stop the foreclosure of the Hernandez family home. Bank of America had the lawsuit removed from state to federal court.
The lawsuit said if not stopped, Bank of America would take "arbitrary and capricious action to sell the Plaintiff's property" It also said Mrs. Hernandez should be "afforded a full hearing in compliance with the due process requirements of the Constitutions of the United States of America and the State of Texas..."
U.S. District Court Judge Sam Cummings disagreed. "… Because Defendants [Bank of America] are not state actors against whom due process requirements apply, Plaintiff is afforded no protection under the United States and Texas Constitutions. As such, Plaintiff has failed to state a claim upon which relief can be granted…"
The ruling prevents the Hernandez family from filing the same lawsuit again in state court. Mrs. Hernandez has 30 days from the ruling to appeal.
Neither Judge Hernandez nor Councilman Hernandez have yet returned calls for comment.
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One of the most outstanding contributors to CW, and all round nice bloke to boot, Fred Fertang has a birthday today.
All the best mate. Hope it's a great day.
One of the most outstanding contributors to CW, and all round nice bloke to boot, Fred Fertang has a birthday today.
All the best mate. Hope it's a great day.
WWCC - Loyaulte Mi Lie
"People make me happy.. not places.. people"
"When a man is tired of London, he is tired of life." - Samuel Johnson
"Hope is the fuel of progress and fear is the prison in which you put yourself" - Tony Benn
Happy birthday to one of the few who place the great Larwood up there with the ATGs.
Terrific bloke, enjoy your day.
What a champ. Happy Birthday Fred.
Happy birthday to one of the awesomest members at CW. Have a good one Fred
And smalishah's avatar is the most classy one by far Jan certainly echoes the sentiments of CW
Yeah we don't crap in the first world; most of us would actually have no idea what that was emanating from Ajmal's backside. Why isn't it roses and rainbows like what happens here? PEWS's retort to Ganeshran on Daemon's picture depicting Ajmal's excreta
Happy birthday. Hope it a great one.
Top chap.
Cricket Web's 2013/14 Premier League Tipping Champion
- As featured in The Independent.
"as much a news event as an actual footballer, a worthy stop-start centre forward, but an all-time hyper-galactico when it comes to doing funny things with cars and hats, a player whose signing proves once again that the Premier League is still undoubtedly the best in the world when it comes to doing things with cars and hats."
- Barney Ronay on Mario Balotelli
Have a good one fella
Every 5 years we have an election and have to decide who are the least obnoxious out of all the men. Then one gets in and they age really quickly. Which is always fun to watch.
Cheers gents, and have been gratified to hear from my delightful daughter - that said neither of my sons has come up with so much as an emailed greeting, yet both will doubtless still be turning up on my doorstep this Thursday seeking three months gratis board and lodging, which just goes to show that daughters are wonderful, and sons can, not to put too fine a point on it, gagf
HB FF. Hope you had a good 'un
Happy Birthday to one of the real legends of CW
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HPV Vaccine Facts All Parents Need to Know
- Tuesday, August 25, 2009
I sat at a picnic table listening to various mothers discussing their hectic schedules trying to keep up with teenage daughters, all on the same sports team. When one mother told of squeezing in an appointment that morning to get her daughter the HPV shot that her doctor recommended, the conversation turned to the necessity to "protect" their girls in such troubling times. I stayed quiet, hoping to learn the values guiding these parents' decisions. Predictably, they had not thought through the issues, nor did they know the facts.
Those mothers were merely following doctors' recommendations and that of all the experts. Gardasil, the HPV vaccine, was approved in 2006 by the U.S. Food and Drug Administration for females as young as nine and up to age 26. It has been marketed as a protection against four types of the human papillomavirus (HPV). Merck, the company that makes Gardasil, claims that the drug will protect against two types of HPV that cause 70 percent of cervical cancers and two types that cause 90 percent of genital warts. Every federal health authority recommends the shots and, according to the Centers for Disease Control and Prevention (CDC), about a quarter of the nation's 13-17 year olds have received the immunizations. The vaccine is on the CDC's vaccine schedule for 11- and 12-year-old girls, and the American Academy of Pediatrics recommends it.
Even so, some physicians remain wary of the trend to give young children a new, largely untried drug. A study in a journal of the American Association for Cancer Research revealed that about half of the doctors in a survey of over a thousand physicians in Texas did not routinely recommend Gardasil for their pre-teen patients.
What those Texas doctors suspected, we now know for sure - that serious concerns are legitimate regarding the use of Gardasil. The highly-promoted, so-called breakthrough vaccine that was recommended for all girls and given to numerous children and teens to prevent possible future cases of cervical cancer, is related to "adverse events" experienced by thousands of girls after taking the vaccine.
In a just-released article in the Journal of the American Medical Association, federal researchers report that after analyzing 12,424 "adverse events" [out of the 13,758 reports of problems as of May 1] voluntarily reported by girls vaccinated with Gardasil that two problems are common. One - fainting - is not inherently serious, but can be if the girl falls and hits her head. The other side effect - "dangerous blood clots" - is quite troubling.. Most of the problems with Gardasil (93 percent) are minor: headache, nausea, and fever. But a disturbing seven percent included hospitalization, permanent disability, life-threatening illness, or death.
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- Behavior Problems
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December 28th, 2011
By Eric Letendre
Years ago I attended a seminar in New Hampshire.
The seminar lasted all weekend and much of it has sifted out of my brain, but I still remember this seminar because of one piece of advice I got.
You see, a British dog trainer by the name of John Rogerson was doing the seminar and at one point he stated:
"In order to have a good dog, you have to learn how to become a good dog owner."
Good dogs have good owners, great dogs have great owners and this really changed the way I looked at training and a lot of things in life.
You also have to understand that when I started training everything was focused on the dog and not the owner.
This led to a lot of problems because the student (the dog) can only be as good as the teacher.
I went home and it completely changed the way I train.
Some amazing things started to happen when I made this change.
I started to enjoy the training process much more and the dogs I worked with were much, much more willing to do the commands and they learned a lot faster.
The trainers that get the best results start by focusing on how they are training their dogs. Some trainers are better at this than others…
…but, anyone can learn how to train this way.
And guess what?
I am gonna prove it to you.
I have extended the Secret Stocking gift for you.
The Secret Stocking has my most popular Online Dog Training Course that shows you step by step how to get the best results from your training sessions.
I have also included TWO bonus gifts.
Check it out before it goes bye bye:
Click Here To See Your Secret Stocking
All the best,