Capital market liberalization has become an irreversible trend in Korea since 1992. With the current level of high interest rate in Korea, however, drastic full-scale liberalization would certainly attract a large amount of capital inflows and appreciate the Korean won. This would affect the price competitiveness of Korean products in international markets, which could bring about significant macro-instability in an economy like Korea which relies heavily upon external transactions. Through simulations using a macro-model based on the neoclassical long-run convergence and the Keynesian short-run dynamics, this paper attempts to provide some quantitative assessments of several alternative policy choices including the speed of liberalization.


We present a versatile method for detecting the presence and motion of a trapped domain wall in a narrow ferromagnetic layer using current-perpendicular-to-plane (CPP) giant magnetoresistance (MR). The CPP-MR response to small motions of the trapped domain wall is enhanced because the CPP current is restricted to the region of wall trapping. We use a Permalloy∕Cu∕Permalloy spin valve in the shape of a long, ∼500-nm-wide wire with a constriction (notch) near its middle that acts as a trapping site for a head-to-head domain wall. Two different notch shapes were studied, mostly at 4.2K but also at 295K.


In a cognitive radio system, licensed primary users can lease idle spectrum to secondary users for monetary remuneration. Secondary users acquire available spectrum for their data delivery needs, with the goal of achieving high throughput and low spectrum charges. Maximizing such a net utility (throughput utility minus spectrum cost) is a central problem faced by a multihop secondary network. Optimal decision making is challenging, since it involves multiple data flows, cross-layer coordination, and economic constraints (budgets of sources). The picture is further complicated by the inter-play between secondary data communication and primary spectrum leasing mechanisms. This work is the first to investigate the full spectrum of socially optimal secondary user communication. We design a social welfare maximization framework for multi-session multi-hop secondary data dissemination based on Lyapunov optimization techniques. A salient feature of the framework is that it takes any given primary user mechanism as input, and produces correspondingly a dynamic, distributed rate control, routing, and spectrum allocation and pricing protocol that can achieve longterm maximization of the overall system utility. Through rigorous theoretical analysis, we prove that our online protocol can achieve a social welfare that is arbitrarily close to the offline optimum, with only finite buffer space requirement at each secondary user, and guarantee of no buffer overflow. Empirical studies are conducted to examine the performance of the protocol.


Aims: The aim of this study was to investigate the current knowledge, skills, and opinions of undergraduate dental students of Qazvin University of Medical Sciences about information communication technology (ICT). A survey was carried out to investigate the capability and attitude of dental students towards computers, using questionnaire.
Materials & Methods: Questionnaires were distributed among undergraduate dental students. All students had access to computers and Internet at the university. Dental students of the second, third, fourth, fifth and sixth years of the dentistry program were asked to complete a questionnaire presented to them at the end of a lecture at the end of the second semester 2008-09.
Results: The response rate was 84.4%. As for free and unrestricted access to computers at the school of dentistry, 93.4% of the students had access to computers at home. All users were computer users. A significant number of students (57.9%) judged themselves proficient in information technology (IT) skills. There was no significant difference between the two sexes about IT. More than 90% of the student acquired their computer skills through sources other than the university. Both sexes used computer to access Internet (78.9%), for word processing (18.4%), multimedia (7.8%), presentations (18.4%), and data management (1.3%). Some students selected more than one item.
Conclusion: Our study revealed a high level of ability to use ICT facilities among dental students. Attention is required to develop interventions that can improve ICT skills. However, the educational use of ICT among Iranian students remains high.


Background Systemic lupus erythematosus (SLE) is an autoimmune disease characterised by a wide range of antibodies reacting with nuclear antigens. Abnormalities in the apoptotic cell death process and apoptotic cell clearance may play an important role in generating these antibodies. Especially antibodies to histones in serum are frequently associated with SLE. Objectives The aims of this study were to evaluate the presence of histones in the cytoplasm of fresh peripheral blood mononuclear cells (PBMCs) and in activated lymphoblasts. The activated lymphoblasts cultured without IL-2 served as a model for apoptosis induction. Methods Human PBMCs were isolated from heparinized peripheral blood of normal donors (n = 6) and activated with 1 μg/ml phytohemagglutinin (PHA) and 10 U/ml IL-2 for the first 5 days. The following two days, the cells were expanded in IL-2 containing medium (0 h). Lymphoblasts were then incubated in IL-2 free medium for 8 or 24 h as well as for 24 h with IL-2 (10 U/ml). Furthermore, lymphoblasts were treated with IL-2 after 8 or 24 h IL-2 deprivation. PBMCs and lymphoblasts were lysed in a modified RIPA-buffer, 20 μg of protein were subjected to denaturing SDS-PAGE. Western blot detection was performed with antibodies against all 5 histones H1, H2A, H2B, H3 and H4 as well as against phosporylated H3 and acetylated H4. Results Only very weak signals of the histones H2A, H2B, H3 and H4 were detected in the cytoplasm of freshly isolated PBMCs, but H1 was undetectable. The activated lymphoblasts showed elevated amounts of all five histones compared to PBMCs. Furthermore, we observed an increased amount of the histones H2A, H2B, H3 and H4 in the cytoplasm in cell culture after another 8 or 24 h without IL-2. Interestingly, the signal intensity of these histones in the cytoplasm decreased significantly after addition of IL-2 to the lymphoblasts after 8 or 24 h IL-2 deprivation. However, no difference of the detectable amount of H1 was noted in activated lymphoblasts compared to preapoptotic lymphoblasts incubated for another 8 or 24 h without IL-2. In addition, for H1 no effect of addition of IL-2 was observed. Lymphoblasts activated with IL-2 for 24 h showed the same signal intensities for the histones H2A, H2B, H3 and H4 as observed for the cells at 0 h. No bands for acetylated H4 or phosporylated H3 were detected in cytoplasm samples in contrast to strong signals in nuclear preparations. Conclusion These results suggest that histones were released from the nucleus into the cytoplasm of preapoptotic human lymphoblasts. The mechanism of the transport of the histones into the cytoplasm is until now unknown. Acetylated H4 and phosporylated H3 were only detected in nuclear extracts which excludes nuclear membrane fragility and nuclear contamination as cause for our findings. In addition, our data indicate that IL-2 can reduce the release of histones from the nucleus into the cytoplasm.


Supercomputer centers often deploy large-scale computing systems together with an associated data analysis or visualization system. In this paper, we propose a co scheduling mechanism, providing the ability to coordinate execution between jobs on different systems. The mechanism is built on top of a lightweight protocol for coordination between policy domains without manual intervention. We have evaluated this system using real job traces from Intrepid and Eureka, the production Blue Gene/P and data analysis systems, respectively, deployed at Argonne National Laboratory. Our experimental results quantify the costs of co scheduling and demonstrate that co scheduling can be achieved with limited impact on system performance under varying workloads.


A molecularly imprinted polymer (MIP)-based impedimetric biosensor was developed for the electrochemical analysis of low-weight biological molecules. Synthetic polymeric matrices with specific and selective recognition sites, which are complementary to the shapes and sizes of the functional groups of analytes, can be prepared using the molecular imprinting method. In this study, a small molecule, tris(hydroxymethyl)aminomethane (TRIS), was used to coat a graphite pencil tip with a TRIS-containing polyacrylamide gel to fabricate a working electrode. The electrode modification and performance were evaluated using cyclic voltammetry and electrochemical impedance spectroscopy. The electrochemical properties of the modified electrodes were observed using an electrochemical cell comprising a Ag/AgCl reference electrode, a Pt wire as the counter electrode, and a pencil graphite tip as the working electrode using a redox-phosphate buffer solution with different concentrations of TRIS and Ethylenediaminetetraacetic acid (EDTA). The I–V and impedance performance of the chemically modified graphite pencil-tip electrodes exhibited decreased conductance and increased impedance correlating with  the increase in TRIS concentration. Thus, MIP-based small-molecule biosensor prototypes can be promising economical replacements over other expensive sensors.


Smart watches have the potential to support health in everyday living by: enabling self-monitoring of personal activity; obtaining feedback based on activity measures; allowing for in-situ surveys to identify patterns of behavior; and supporting bi-directional communication with health care providers and family members. However, smart watches are an emerging technology and research with these devices is at a nascent stage. Seventy-three studies were returned in the search. Seventeen studies published were included. Included studies were published from 2014 to 2016, with the exception of one published in 2011. Most studies employed the use of consumer-grade smart watches (14/17, 82%). Patient-related studies focused on activity monitoring, heart rate monitoring, speech therapy adherence, diabetes self-management, and detection of seizures, tremors, scratching, eating, and medication-taking behaviors. Most patient-related studies enrolled participants with few exclusion criteria to validate smart watch function (10/17, 58%). Smart watch technical function, acceptability, and effectiveness in supporting health must be validated in larger field studies that enroll actual participants living with the conditions these devices target.


ABSTRACT.
 Resident or short-distance migrant birds that occupy urban habitats are known to breed earlier than nearby rural populations, but similar data on long-distance tropical migrants are lacking. To understand the relationship between urbanization and reproductive phenology of a tropical migratory bird species, we (1) described variation in patterns and consequences of breeding phenology across an urban-to-rural gradient and (2) assessed underlying reasons why phenology may be related to urbanization. We studied Acadian Flycatchers (Empidonax virescens) between 2001 and 2007 in 35 forests spanning an urban-to-rural gradient in central Ohio. The general pattern of breeding phenology was opposite of that described for most resident and short-distance migrant birds. At higher levels of urbanization, site arrival dates and clutch initiations were later and cessation of breeding was earlier than in forests of more rural landscapes. The phenological shifts reduced the length of the nesting season in urban landscapes, with the result that birds in more urban landscapes initiated fewer nests and fledged fewer young than their rural-breeding counterparts. Underlying causes of phenological differences are less clear. One possibility supported by our data is that urban forests are less desirable and selected later by smaller females, which initiated first clutches later in the nesting season than larger females. This study provides the first evidence that urbanization is associated with attenuated nesting seasons for tropical migratory birds and that this shift in breeding phenology may have reproductive consequences.


ABSTRACT The Ebola outbreak that started in 2014 had infected 28,652 people and taken more than 11,325 lives by spring 2016. Along with this infectious disease pandemic, a pandemic of fear surfaced, especially on social media platforms. Yet little is known about the types of communications, the larger ecological context, and the associated risk perception factors that were present in the social media discussion. This study focused on the social media platforms Twitter and Pinterest and analyzed tweets and pins through the lens of a risk communication theory, the Risk Perception Model, as well as a health behavior theory, the Health Belief Model. Large differences were found in the presence of risk perception variables and health behavior variables between the two platforms, and recommendations for public health practitioners to address fear, anger, and attitudinal biases related to Ebola are included.


Wood-plastic composites (WPCs) are currently discarded using incineration treatment, which is very expensive. Hence, this study was performed to improve the biodegradation of WPCs, such that they could potentially be buried after use, and to estimate their bending strength. A biodegradation test (determining the ultimate aerobic biodegradability of plastic materials under controlled composting conditions) was performed according to ISO 14855-1. Two groups of specimens were prepared using rice-bran mixture as the bioresource. One group contained rice-bran mixtures of 5, 7.5, and 10 wt.% instead of wood flour contents, and another group contained rice-bran mixtures of 8, 16, and 24 wt.% instead of the talc component. During the 20 days of the biodegradation experiment, the WPC (control) showed 18% biodegradation, and 7.5%-rice-bran-mixture-added specimen showed the highest biodegradation of 32%. Furthermore, the bending strength (MOR) was increased by up to 140% by adding rice-bran mixture as a biodegradable component. Therefore, the rice-bran mixture improved the biodegradation and mechanical properties of WPCs.


The possibility of a strongly first-order electroweak phase transition by means of a dimension-six Higgs operator in the Higgs potential of the standard model is studied at finite temperature at the one-loop level. Exact calculation of the one-loop effective Higgs potential at finite temperature suggests that for the Higgs boson with its mass between 115 and 132 GeV the strongly first-order electroweak phase transition is possible if a dimension-six operator is present.


An anomalously strong volume magnetostriction in Invars may lead to a situation when at low temperatures the dislocation free energy becomes negative and a multiple generation of dislocations becomes possible. This generation induces a first order phase transition from the FCC crystalline to an amorphous state, and may be called " cold melting ". The possibility of the cold melting in Invars is connected with the fact that the exchange energy contribution into the dislocation self energy in Invars is strongly enhanced, as compared to conventional ferromagnetics, due to anomalously strong volume magnetostriction. The possible candidate, where this effect can be observed, is a FePt disordered Invar alloy in which the volume magnetostriction is especially large.


The article touches upon the issues of several problems. Firstly, we attempt to determine the methodology of a sociological analysis of culture which is adequate for modern realities. Secondly, we will apply this methodological basis to the cultural specifics of modern Russian students in a transitive, transitional society. It is stressed that the formation of a global innovative society results in a permanent crisis with the destruction of the old sociocultural forms and the emergence of new ones, with the result that culture becomes not a "guardian of the foundations", but an active "fermenting" power of society. In these nonlinear processes, a special importance is acquired by subjective culture. Based on F. Tenbrook's ideas, an analysis of monostylism and polystylism of a student's representative culture is carried out. It is noted that these processes of representation are contradictory and hybrid. Highly-valued by student youth, the values of independence, individuality, and freedom of the post-materialistic plan are represented primarily in the sphere of leisure and free-time activities. The presented typology of students' lifestyles in the field of educational activity ("professionals", "ritualists", "public men", and "conformists") fixes a predominantly adaptive strategy of behavior based on the adoption of a paternalistic attitude on the part of the administration and the teaching staff of universities. The article is based on the materials of the authors' interregional sociological research, conducted in the Southern Federal District in 2006, 2011, and 2016.


Two different routes that enable the electrostatic grafting of cationic single‐molecule magnets (SMMs) onto the surface of chemically modified anionic multi‐walled carbon nanotubes (MWNTs) are described. The chemical nature and physical properties of the resulting hybrids are discussed on the basis of a complete battery of experimental techniques. The data show that the chemical nature of the SMM unit remains intact, while its magnetic response is significantly affected by the grafting process, which is likely due to surface effects.


This paper introduces and examines Confucius Institutes (CI) as part of China's soft power – with a special focus on the problems regarding the CI's in Hungary. I also intend to analyse what kind of picture of the CI's the mediapresents and how realistic this image is. I will discuss in two separate chapters the most serious accusations made against the CI's (spreading Chinese propaganda, violation of human rights and academic freedom and spying forChina) because I consider that these topics provide valuable insights into the considerable influence exercised by the media even in the case of assessing educational and cultural institutions. The term "soft power" was introduced by Joseph Nye in 1990, referring to the ability to make the image of one's country desirable abroad by using culture, ideology or institutions. But China had already discovered in the 80s how important culture and language can be as means to obtain power without recourse to "hard" methods. In 1987 China established Hanban; the first experimental CI was set up in 2004 in Uzbekistan and the first official CI was founded in South Korea in the same year. As of April, 2020 there are 540 CI's world-wide, according to Hanban's website, which clearly indicates that the CI's are hugely successful. In Hungary there are currently 5 CI's.


The conventional methods using color signal for tracking the movement of the object require a lot of calculation and the performance is not accurate. In this paper, we propose a method to effectively track the moving objects using the depth information from a depth camera. First, it separates the background and the objects based on the depth difference in the depth of the screen. When an object is moved, the depth value of the object becomes blurred because of the phenomenon of Motion Blur. In order to solve the Motion Blur, we observe the changes in the characteristics of the object (the area of the object, the border length, the roundness, the actual size) by its velocity. The proposed algorithm was implemented in the simulation that was applied directly to the tracking of a golf ball. We can see that the estimated value of the proposed method is accurate enough to be very close to the actual measurement.


Since the end of World War II, there has appeared in American medicine a new "specialist," the director of medical education. His role in graduate and postgraduate medical education is widely misunderstood by the practicing profession, hospital administrators, and medical school officials. Scores of non-university hospitals have established positions for a part-time or full-time educational director, with the expectation that he will create an outstanding program for interns, residents, and visiting staffs, magically solving current critical manpower shortages. Moreover, too often these appointments have been filled by unqualified or partially informed men. If these trends continue, it is certain that widespread dissatisfaction and disappointment will develop, tending to discredit an important contribution to the establishment of non-university hospitals as teaching institutions. Twenty years ago the report of the Commission on Graduate Medical Education 1 described the concept of the director of medical education, outlined his responsibilities, and concisely delineated the


Over the past 50 years the Sherpa-inhabited Mt Everest region of Nepal has become a premier international mountaineering and trekking destination. Tourism development has brought prosperity to many Sherpas. It has also, however, had adverse impacts on regional forests and alpine vegetation because of the use of firewood by camping groups and inns and the felling of trees to construct inns and other tourist facilities. Concern that tourism was causing widespread deforestation helped catalyse the 1976 establishment of an inhabited protected area, Sagarmatha (Mt Everest) National Park, in the Khumbu region and spurred the implementation of a series of forest conservation and alternative energy development measures both within the national park and in a recently declared buffer zone in the adjacent Pharak region. This paper examines the changing pressures that tourism has placed on regional forests and alpine vegetation over the past half century and their role in regional vegetation change. This analysis is based primarily on detailed accounts of past and present forest use and change obtained during fieldwork conducted in all Khumbu and Pharak villages, along with corroborating evidence from early foreign visitors' accounts and photographs. Contrary to some early reports it now appears there has actually been little deforestation since 1950. The continuing use of firewood by inns, however, has contributed to the thinning of forests in some parts of the national park and to the depletion of shrub juniper in the most heavily visited alpine regions. There has been a greater impact on forests just outside the national park, which have been heavily thinned over an extensive area in order to provide timber to build inns within the national park.


Background Efficacy and safety of tocilizumab (TCZ), an interleukin-6 receptor inhibitor, were previously demonstrated at week 104 of CHERISH, a phase 3 trial in patients with polyarticular course juvenile idiopathic arthritis (pcJIA).1 Objectives The purpose of this analysis was to evaluate the long term safety and efficacy of tocilizumab (TCZ) treatment with pcJIA in patients from Poland and Russia who entered this extension study. Methods 41 patients with pcJlA from Poland (18) and Russia (23), who had completed CHERISH1 (104 weeks) with at least juvenile idiopathic arthritis (JIA) American College of Rheumatology (ACR30) clinical response to TCZ relative to baseline in core study with no adverse events (AEs), serious adverse events (SAEs) or conditions that could lead to unacceptable risk of continued treatment were enrolled. Patients received TCZ therapy 8 mg/kg in intravenous infusion every 4 weeks. As a result of early study termination patients had varying durations of time in the study ranging from 27 to 89 weeks. Results The safety population comprised 41 patients with 46.41 patient-years (PY). It should be emphasized that at the start of the study, each patient received the drug for 104 weeks. Rates/100 PY of adverse events (AEs) and serious AEs (SAEs) were 181.0 and 6.46, respectively. Pharyngitis and upper respiratory tract infection were the most common AE (14,6% and 12,2% respectively). With the exception of 1 patient who had severe neutropenia that led to withdrawal from the study, all other AEs were mild (24.4%) or moderate (29.3%) in intensity and did not lead to withdrawal. There were no deaths, life-threatening AEs, or AEs of special interest during this study. The incidence of SAEs was low (3 patients – 7,3%): mild proteinuria, severe neutropenia and moderate multiple injuries. The majority of AEs were unrelated to TCZ and were consistent with a pediatric and pcJIA population. There were no new safety findings of note for laboratory and vital sign parameters. All patients in this study achieved ACR70 at Baseline (Week 104 of the core study) and continued to achieve at least ACR50 response up to Week 24 of this long-term extension study. Other efficacy parameters showed similar patterns of continued response across the first 24 weeks of this long-term extension study. Conclusions The long-term use of TCZ was well tolerated in population of pcJIA patients. The safety profile of TCZ treatment consistent with reported previously.1 Efficacy of TCZ was maintained over 2,5 years of treatment. The continued efficacy response and the consistent safety profile currently support a positive benefit-risk ratio for the use of TCZ in pcJIA. References Brunner HI et al. Ann Rheum Dis doi:10.1136/annrheumdis-2014-205351 Disclosure of Interest V. Opoka-Winiarska: None declared, E. Smolewska: None declared, Z. Żuber: None declared, G. Dębowska Employee of: Roche Polska Sp. z o.o.


This paper examines the impact of compression methods on the long-range dependence of communication network traffic measurements. The two compression methods that are examined are based on the Wavelet transformation and the Discrete Cosine Transformation (DCT). In order to measure the length of long-range dependence of a stochastic process, we first have to estimate the Hurst parameter. The Hurst parameter is estimated by using the rescaled range statistic (R/S) method. The Hurst values of the examined signal, before and after the applied compression, are estimated and compared. If the Hurst value of the compressed signal i s close to the Hurst value of the uncompressed signal, then the compression algorithm has little interference on the longrange dependence. The results show that Wavelet transformation performs better than the DCT.


This quantitative causal-comparative study compared perceptions of professional development opportunities between high-achieving and low-achieving elementary-middle school teachers in an urban school district using the Standards Assessment Inventory (SAI). A total of 271 teachers participated including 134 (n=134) teachers from high-achieving schools, and 137 (n=137) teachers from low-achieving schools. Teachers in high-achieving schools reported receiving professional development more aligned to the 12 National Standards Development Council (NSDC) standards for quality professional development than teachers in low-achieving schools. In addition, teachers in high-achieving schools indicated receiving professional development modeled as Professional Learning Communities (PLCs). Findings suggest that high quality professional development designed with elements of professional learning communities contribute to higher student achievement.


Three amphiphilic block polypeptides, (sarcosine)m‐b‐(l‐ or d‐Leu‐Aib)n (L16, D16, D14), having different helical chain lengths or helicity are synthesized. A mixture of L16, D16, and D14 generates vesicles of diameters more than ca. 130 nm by injecting the ethanol solution into water and heating at 90°C for 1 h. On the other hand, when nanotubes composed of L16 and D14 having ca. 50 nm diameter are mixed with nanosheets composed of D16, smaller and homogeneous vesicles of ca. 60 nm diameter are obtained with the heat treatment. The time lapse TEM image analysis of the mixtures revealed some transient structures of nanotubes sticking a nanosheet or a vesicle at the open end of nanotubes. The precise size control of vesicles is therefore attainable by using nanotubes as a structural template regulating the size of vesicles near to the nanotube diameter upon the membrane fission processes.


Proceedings: AACR 102nd Annual Meeting 2011‐‐ Apr 2‐6, 2011; Orlando, FL

Cellular senescence is a proven tumor-suppressive strategy that forces transformed cancer cells to re-enter irreversible cell-cycle arrest. Triggering the senescence of tumor cells may contribute to successful cancer therapy. α-Catulin, an α-catenin-related protein, is reported to have tumorigenic potential because it regulates the NF-κB pathway, but little is known about its clinical relevance and the mechanism through which it regulates cancer progression. Here, we provide evidence that the expression of α-catulin is upregulated in most human cancer cells and clinical oral cancer tissues and positively correlated with tumor size (P = 0.001) and cancer stage (P = 0.004) of OSCC. α-Catulin knockdown in the OC2 and A549 cancer cell lines dramatically decreased cell proliferation and contributed to cellular senescence, and inhibited OC2 xenograft growth. Mechanistic dissection showed that α-catulin depletion strongly induced the DNA damage response (DDR) via a p53/p21-dependent pathway in A549 cells, but a p53/p21-independent pathway in OC2 cells carrying mutant p53. Global gene expression analysis revealed that α-catulin knockdown altered several crucial genes related to mitotic chromosome condensation, DDR, and DNA repair systems, which suggests that its depletion-induced cellular senescence might be caused by chromosome condensation failures, severe DNA damage, and impaired DNA repair ability. Our study provides evidence that α-catulin promotes tumor growth by preventing cellular senescence and suggests that downregulating α-catulin may be a promising therapeutic approach for cancer treatment.

Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 102nd Annual Meeting of the American Association for Cancer Research; 2011 Apr 2-6; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2011;71(8 Suppl):Abstract nr 1225. doi:10.1158/1538-7445.AM2011-1225


The boundary between land and water is one of the most difficult of all boundaries to
re-define. The changing nature of watercourse systems poses major problems and
surveyors currently have limited guidelines to assist in the process of selecting an
appropriate natural feature to use for a boundary alignment.
This project has been undertaken to address uncertainty in Queensland legislation
with regard to non-tidal riparian boundaries. The current approach regarding the
boundary between land and non-tidal water is defined by the term - bed and banks.
The methods adopted by surveyors in determining a natural feature are drawn upon
using their experience alone rather than a combination of experience and theoretical
knowledge in solving this problem
Addressing short falls in bed and bank descriptions has allowed a greater
understanding of these types of boundaries.
The formulation of principals and standards of the definition process has enabled
thorough guidelines to be developed. The project addresses key topics of riparian
boundary reinstatement by:
• Identification of the needs of society for riparian boundaries and the key
principles essential to meeting those needs
• Develop a set of standards to address these key principals, and
• Develop a guideline to aid surveyors in an appropriate definition process.
These developments have enabled a transparent approach to be achieved with the
relationship between the surveyor and regulation.
The current system of reporting outlined in the Cadastral Survey Requirements,
compromises the ability of the system to cater for society's needs. A guideline for the
surveyor to refer to when determining an appropriate natural feature to locate would
be an invaluable resource. This reference tool would potentially address a deficiency
in the current system thereby satisfying the greater community.


This paper reviews the capacity (number, quality and motivation) of the extension personnel in Nigeria; and describes farmers' perception of the quality of extension service delivery using evidences from literature, reports of organizations as well as experiences from field research. Findings reveal a tremendous shortage in the number and quality of extension personnel across the country as major reason for the poor performance of the ADPs thereby leaving no hope for the "beautiful" transformation agenda. This paper strongly recommends immediate recruitment of new hands as well as full implementation of a well-designed capacity building programme so as to ensure a sustainable extension service delivery system where extension personnel can operate in the expected commercial (agriculture-driven) economy. Keywords : Capacity building, training, extension personnel, sustainability, Agricultural transformation Agenda (ATA)


Simple and sensitive methods for the determination of ultramicro amounts of aluminium with haematoxylin and its oxidised form in the presence of cetyltrimethylammonium bromide are described. The complexes formed obeyed Beer's law in the ranges 15–175 and 25–250 µg l–1 using haematoxylin and oxidised haematoxylin, respectively. The best results for chelate formation were obtained at pH 7.6 and 7.0 with molar absorptivities of 1.7 × 105 and 1.1 × 105 l mol–1 cm–1, respectively. The values of Sandell's sensitivity were 0.0002 and 0.0003 µg cm–2, respectively. The effect of 25 interfering ions was studied. The method has been applied to the determination of aluminium in iron and steel.


Background: Enterocytozoon bieneusi is a zoonotic pathogen with a wide range of animal host. In China, there are only a few reports of E. bieneusi infection in wild populations of Rhesus macaque. Here, we determined the prevalence of E. bieneusi in 9 populations of Rhesus macaque and assessed their zoonotic potential.Methods: A total of 324 fecal samples of Rhesus macaque were collected from 9 populations in 5 provinces (Sichuan, Chongqing, Qinghai, Tibet and Hainan) in China, and performed genotype of ITS gene to analyze the zoonotic potential.Results: 38 of the 324 (11.72%) specimens from wild Rhesus macaques were infected with E. bieneusi. 11 genotypes were identified including 3 known genotypes: D (n= 24), EbpC (n= 4) and SCC-2 (n= 1); 8 novel genotypes named Mul6 (n= 1), Mul7 (n= 1), Mul8 (n= 1), Mul9 (n= 1), Mul10 (n= 2), Mul11 (n= 1), Mul12 (n= 1) and Mul13 (n= 1). According to the phylogenetic analysis, Mul6, Mul7, Mul8, Mul9, Mul11 Mul12 and Mul13 were clustered into Group 1, while Mul10 were clustered into Group 5.Conclusions: To the best of our knowledge, this is the first study reporting the prevalence and genotypes of E. bieneusi in several wild populations of Rhesus macaque in China. It is concluded that, population of Rhesus Macaques is likely to prone of E. bieneusi transmission in many regions of China, which found the zoonotic genotypes D and EbpC and the novel genotypes with zoonotic potential, it should be paid more attention to prevent.


We study transport across a magnetic impurity by means of a recently developed slave-spin technique that does not require any constraint. Within a conserving mean-field approximation we find a conductance that displays both the known zero-bias anomaly but also the expected peak at bias of order U. We extend the slave-spin mean-field approximation to study the out of equilibrium transient evolution of a quantum dot. We apply the method to investigate the time-evolution of a quantum dot induced by a time-dependent electrochemical potential applied to the contacts. Similarly to the time-dependent Gutzwiller approximation, the mean-field slave-spin dynamics is able to capture dissipation in the leads, so that a steady-state is reached after a characteristic relaxation time.


Pre-training a diverse set of neural network controllers in simulation has enabled robots to adapt online to damage in robot locomotion tasks. However, finding diverse, high-performing controllers requires expensive network training and extensive tuning of a large number of hyperparameters. On the other hand, Covariance Matrix Adaptation MAP-Annealing (CMA-MAE), an evolution strategies (ES)-based quality diversity algorithm, does not have these limitations and has achieved state-of-the-art performance on standard QD benchmarks. However, CMA-MAE cannot scale to modern neural network controllers due to its quadratic complexity. We leverage efficient approximation methods in ES to propose three new CMA-MAE variants that scale to high dimensions. Our experiments show that the variants outperform ES-based baselines in benchmark robotic locomotion tasks, while being comparable with or exceeding state-of-the-art deep reinforcement learning-based quality diversity algorithms.


Topic-based intelligent content design with a better understanding of semantic web schemas could be the new focus for technical communication (TC) pedagogy in academia - a major shift away from designing standalone static documents. A new such TC course focused on the basics of how XML, RDFS, and OWL schema contribute to the semantic web for CCMS and CDP, including the basics of how faceted search works and ontology creation happens for simple e-commerce based, tourism, healthcare, and consumer product information design. The course also attempted to expose students to a basic understanding of iiRDS – the standard that enables dynamic information request and delivery in the era of the Internet of Things and Industry 4.0; and how Microsoft HoloLens - a mixed reality platform caters to intelligent information processing in Toyota and smart city contexts, as case studies. This was an introductory course with conceptual development being the focus, and not programming skills. With this course, we wanted to introduce students to the new industry documentation standards and initiate a process in pedagogy that will ultimately lead to bridging the extreme shortage of qualified job applicants in the industry coming from content strategy as a new field of practice. This paper focused on a pilot study initiating an exercise to explore the extent to which such a course helps teach information management in an English as Foreign Language (EFL) context for computer science majors, within the scope of content language integrated learning (CLIL) and project-based language learning (PBLL).


This study focuses on determinants of elderly labour force participation and retirement decisions in the Netherlands. This is analysed by a dynamic programming model for the simultaneous choice of retirement age and route, which includes social insurance and private pensions, eligibility conditions for early retirement, lifecycle wage and health profiles, and layoffs. Special attention is given to opportunities for and the effect of participation policies. Results show that institutional structures of benefit and pension programmes are prime determinants of retirement, particularly eligibility conditions and potential substitution between exit routes, and that dynamic aspects are relevant for understanding retirement behaviour. Copyright © 2004 John Wiley & Sons, Ltd.


Conventional stochastic rounding (CSR) is widely employed in the training of neural networks (NNs), showing promising training results even in low-precision computations. We introduce an improved stochastic rounding method, that is simple and efficient. The proposed method succeeds in training NNs with 16-bit fixed-point numbers and provides faster convergence and higher classification accuracy than both CSR and deterministic rounding-to-the-nearest method.


Consider the usual experience of a student who progresses far enough in school mathematics to begin to study the calculus. After motivation of the topic of "rates of change", simple differentiation of polynomials is learned. More advanced functions are then considered, and eventually the student meets the product, quotient and chain rules. The result: with enough algebraic accuracy and persistence, the student can determine derived functions for virtually any sufficiently wellbehaved combination of standard functions.


Abstract An essential feature of replication initiation proteins is their ability to bind to DNA. In this work, we describe a new domain that contributes to a replication initiator sequence-specific interaction with DNA. Applying biochemical assays and structure prediction methods coupled with DNA–protein crosslinking, mass spectrometry, and construction and analysis of mutant proteins, we identified that the replication initiator of the broad host range plasmid RK2, in addition to two winged helix domains, contains a third DNA-binding domain. The phylogenetic analysis revealed that the composition of this unique domain is typical within the described TrfA-like protein family. Both in vitro and in vivo experiments involving the constructed TrfA mutant proteins showed that the newly identified domain is essential for the formation of the protein complex with DNA, contributes to the avidity for interaction with DNA, and the replication activity of the initiator. The analysis of mutant proteins, each containing a single substitution, showed that each of the three domains composing TrfA is essential for the formation of the protein complex with DNA. Furthermore, the new domain, along with the winged helix domains, contributes to the sequence specificity of replication initiator interaction within the plasmid replication origin.


The results of the examination and treatment of a patient with frequent ventricular ectopy are presented in the article. During ablation of an ectopic focus in the left coronary sinus of the aorta, as a result of dislocation of the ablation catheter, a spasm of the left coronary artery has been diagnosed.


Walsh-type signals exciting memoryless power-law systems are considered. The input is assumed to consist of a sum of weighted Walsh functions. A method is given for finding the weights of the Walsh functions in the output when the input is a finite Walsh series. It is shown that the fast Walsh transform can be used to facilitate the necessary computation.


Vascular endothelial growth factor (VEGF)–induced breakdown of the blood-retinal barrier requires protein kinase C (PKC)β activation. However, the molecular mechanisms related to this process remain poorly understood. In this study, the role of occludin phosphorylation and ubiquitination downstream of PKCβ activation in tight junction (TJ) trafficking and endothelial permeability was investigated. Treatment of bovine retinal endothelial cells and intravitreal injection of PKCβ inhibitors as well as expression of dominant-negative kinase was used to determine the contribution of PKCβ to endothelial permeability and occludin phosphorylation at Ser490 detected with a site-specific antibody. In vitro kinase assay was used to demonstrate direct occludin phosphorylation by PKCβ. Ubiquitination was measured by immunoblotting after occludin immunoprecipitation. Confocal microscopy revealed organization of TJ proteins. The results reveal that inhibition of VEGF-induced PKCβ activation blocks occludin Ser490 phosphorylation, ubiquitination, and TJ trafficking in retinal vascular endothelial cells both in vitro and in vivo and prevents VEGF-stimulated vascular permeability. Occludin Ser490 is a direct target of PKCβ, and mutating Ser490 to Ala (S490A) blocks permeability downstream of PKCβ. Therefore, PKCβ activation phosphorylates occludin on Ser490, leading to ubiquitination required for VEGF-induced permeability. These data demonstrate a novel mechanism for PKCβ targeted inhibitors in regulating vascular permeability.


A Gram-positive-staining, aerobic, non-endospore-forming bacterial strain (JJ-59T), isolated from a field-grown maize plant in Dunbar, Nebraska in 2014 was studied by a polyphasic approach. Based on 16S rRNA gene sequence similarity comparisons, strain JJ-59T was shown to be a member of the genus Paenibacillus, most closely related to the type strains of Paenibacillus aceris (98.6 % 16S rRNA gene sequence similarity) and Paenibacillus chondroitinus (97.8 %). For all other type strains of species of the genus Paenibacillus lower 16S rRNA gene sequence similarities were obtained. DNA-DNA hybridization values of strain JJ-59T to the type strains of P. aceris and P. chondroitinus were 26 % (reciprocal, 59 %) and 52 % (reciprocal, 59 %), respectively. Chemotaxonomic characteristics such as the presence of meso-diaminopimelic acid in the peptidoglycan, the major quinone MK-7 and spermidine as the major polyamine were in agreement with the characteristics of the genus Paenibacillus. Strain JJ-59T shared with its next related species P. aceris the major lipids diphosphatidylglycerol, phosphatidylglycerol, phosphatidylethanolamine and an unidentified aminophospholipid, but the presence/absence of certain lipids was clearly distinguishable. Major fatty acids of strain JJ-59T were anteiso-C15 : 0, iso-C15 : 0 and iso-C16 : 0, and the genomic G+C content is 47.2 mol%. Physiological and biochemical characteristics of strain JJ-59T were clearly different from the most closely related species of the genus Paenibacillus. Thus, strain JJ-59T represents a novel species of the genus Paenibacillus, for which the name Paenibacillus nebraskensis sp. nov. is proposed, with JJ-59T (=DSM 103623T=CIP 111179T=LMG 29764T) as the type strain.


This research on the images of Thai women in a magazine for older adults aims to analyze the structure and components of interview columns and examines the linguistic strategies used to present images of Thai women within the context of a magazine for older adults by associating textual analysis with visual methodology. The data collection in this research was grounded on O-lunla magazine, a magazine targeting people in their 60s and older. Twenty-two interview columns from ten magazine issues from January 2017 to October 2017 were included. The study discloses how this magazine for older adults defines the meaning of ageing and the role of the magazine in passing particular notions about desirable ageing and images of older women in Thai society through the use of linguistic strategies, as well as emphasizing the concepts of desirable ageing for women. The results with regard to the content reveal that the meanings of ageing and the images of Thai women in their older age in this magazine for older adults are formed in a positive way. That is to say, older women are depicted as archetypes of a pleasant life in terms of happiness, work and health.


The converter topologies identified as diode-clamped multilevel (DCM) or, equivalently, as multipoint clamped (MPC), are rarely used in industrial applications, owing to some serious drawbacks involving mainly the stacked bank of capacitors that constitutes their multilevel DC link. The balance of the capacitor voltages is not possible in all operating conditions when the MPC converter possesses a passive front end. On the other hand, in AC/DC/AC power conversion, the back-to-back connection of a multilevel rectifier with a multilevel inverter allows the balance of the DC-link capacitor voltages and, at the same time, it offers the power-factor-correction capability at the mains AC input. An effective balancing strategy suitable for MPC conversion systems with any number of DC-link capacitors is presented here. The strategy has been carefully studied to optimize the converter efficiency. The simulation results related to a high-power conversion system (up to 10 MW) characterized by four intermediate DC-link capacitors are shown.


We, the Editors and Publisher of the Journal of Receptors and Signal Transduction, have retracted the below article: Baicalin suppresses the progression of preeclampsia via regulating miR-155-5p/FOXO3 axis; Bin Caia, Yali Hua, Jihong Peng & Ting Song; Journal of Receptors and Signal Transduction; https://doi/10.1080/10799893.2020.1870493 Since publication, concerns have been raised about the integrity of the data in the article. When approached for an explanation, the authors checked their data and confirmed there are fundamental errors present. Therefore, they have agreed to the retraction of this article. We have been informed in our decision-making by our policy on publishing ethics and integrity and the COPE guidelines on retractions. The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as 'Retracted'.


People with facial deformities often use prosthetic devices to restore their normal visual appearance. A prosthesis device is a custom-sculpted artificial facial feature made of silicon that is worn to cover deformity and restore form and hopefully function of the feature. Surface scanning, computer-aided design, and rapid prototyping technologies are being used to create and evaluate these customized prostheses. The geometry of the patient's existing facial features can be captured in few seconds using non-contact 3D scanners. However, the resultant point data set is very large and corrupted and should be reduced to reconstruct accurate facial surface. It is also equally important to evaluate the fitting characteristics of designed prosthetic device on patient's face for realistic effects. In this paper, an integrated contour-based algorithm is presented, that facilitates a unified approach for data simplification and surface modeling of face and prosthetic device. For data simplification, an ordered sequence of contours from a dense unstructured point cloud data is extracted and simplified as B-spline curves with a reduced number of control points. The simplified-extracted contours are then used to generate the facial lofted surface. This facial model is then used for modeling and fitting evaluation of the prosthetic device. A prosthetic device is designed using contour matching of a generic feature model and the patient's facial model to ensure its fitting accuracy on patient's facial features. Facial data with a simulated nasal deformity is used to illustrate this methodology. The effectiveness of the method can be improved by increasing the number of parallel contours, and using a larger second stage reduction ratio during data simplification.


Standard cell libraries provide designers with a fixed set of well characterized logic blocks. As designs are pushed for high performance, low area, and low power, it is essential to have a, good standard cell library that can help achieve these goals. As gate sizing is crucial to timing, the number of gate sizes (drive strengths) available for each of the primitives is an important factor to be considered. While an infinite granularity of gate sizes is preferable to get the best entitlement, it is often impractical due to the huge cost associated with developing and maintaining libraries. It is therefore essential to find ways to achieve the best performance, power and area, with a, reasonable library size. In this paper we focus on the problem of finding out the optimal ratio of gate sizes to be selected. 65nm libraries were used for validating the claims on a real design and the results are presented in this paper


Background: This study aimed at determining the incidence of low birth weight among live births and maternal anaemia and to investigate the association between some maternal factors and birth weight. Methods: This was a retrospective cross sectional study that involved mothers who regularly attended antenatal clinics and had delivered singleton live births between January 2014 to December 2014 in the University of Cape Coast Hospital, Cape Coast, Ghana. Results: Out of the 405 newborns included in the study, 194 (47.90%) were females and 211 (52.10%) males with a mean birth weight of 3.25±0.52kg. There was a low birth weight prevalence of 7.7% and a maternal anaemia prevalence of 38.8%. The period of gestation (p=0.00001), maternal anaemia (p=0.0217) and maternal age (p=0.0030) were found to be significantly associated with birth weight. Sex of baby (p=0.6668), parity of mother (p=0.6959) and maternal sickling status (p=0.7915) were not significantly associated with birth weight. Conclusions: As far as low birth weight is concerned, frequency is not high among live babies born to mothers who regularly attended antenatal clinics. This agrees with studies that suggest that antenatal clinic attendance positively affects birth weight. Thus in order to reduce the high prevalence of low birth weight and maternal anaemia in developing countries all pregnant women must be encouraged to attend antenatal clinics regularly.


The poly((para-(4-methylpiperazin-1-yl)methanone)phenylacetylene) (PPA) polymer with a 66% trans-cisoid configuration was used to prepare a π-conjugated ionic polyacetylene network gel (π-IPN gel) by a simple cross-linking reaction between PPA and suberic acid in an appropriate functional group ratio. The PPA hydrogel could be synthesized in bulk quantities with a uniform morphology of self-assembled interconnected nanospheres. In addition, experimental results revealed that the PPA-based π-IPN gel led to an enhanced electrical storage ability and demonstrated immense potential for use in flexible solid-state energy storage devices.


Abstract Purpose: The study evaluated safety and efficacy of olaratumab + pembrolizumab in patients with unresectable locally advanced/metastatic soft-tissue sarcoma (STS) with disease progression on standard treatment. Patients and Methods: This was open-label, multicenter, nonrandomized, phase Ia/Ib dose-escalation study followed by cohort expansion (olaratumab + pembrolizumab intravenous infusion). Primary objectives were safety and tolerability. Results: The majority of patients enrolled (n = 41) were female [phase Ia: 9 of 13, phase Ib/dose-expansion cohort (DEC), 17 of 28], aged < 65 years. In phases Ia and Ib, 13 and 26 patients received prior systemic therapy, respectively. Patients received olaratumab 15 mg/kg (phase Ia; cohort 1) or 20 mg/kg (phase Ia; cohort 2 and phase Ib) and pembrolizumab 200 mg (phase Ia/Ib). The median (Q1–Q3) duration of therapy (olaratumab) was 6.0 (3.0–11.9; cohort 1), 14.4 (12.4–20.9; cohort 2), and 14.0 (6.0–21.8) weeks (DEC). No dose-limiting toxicities and few grade ≥ 3 treatment-emergent adverse events [TEAE; 15 mg/kg: 2 (increased lipase); 20 mg/kg: 1 (increased lipase), 1 (colitis), 2 (diarrhea), 3 (anemia)] were reported. Two TEAEs (increased lipase) were related to study discontinuations. Twenty-one patients reported mild (grade ≤ 2) TEAEs [phase Ia, disease control rate (DCR):14.3% (1/7, cohort 1); 66.7% (4/6, cohort 2); no responses were reported; phase Ib, DCR: 53.6% (15/28); objective response rate: 21.4% (6/28; RECIST and irRECIST criteria)]. No response was observed in patients with programmed death ligand-1–positive tumors. Conclusions: Antitumor activity was observed in some patients in DEC, and combination was well tolerated with manageable safety profile. Further studies are warranted to evaluate the efficacy and mechanistic impact of platelet-derived growth factor receptor inhibitors with immune checkpoint modulator coadministration.


This paper reports on an empirical study about the mechanisms of the collaboration of drivers and navigators in Pair Programming (PP) sessions. Based on video recordings of professional software developers, we analysed the mechanisms of role switches and how developers split the task of driving. We found that developers do not evenly contribute to the task of driving and that they spend on average a third of the session without any computer interaction focusing mainly on communication. In addition, our results show that most pairs switch roles frequently and that the frequency and fluidity of switches indicate a high level of engagement on the part of both developers.


Processing data streams in near real-time is an increasingly important task. In the case of event-timestamped data, the stream processing system must promptly handle late events that arrive after the corresponding window has been processed. To enable this late processing, the window state must be maintained for a long period of time. However, current systems maintain this state in memory, which either imposes a maximum period of tolerated lateness, or causes the system to degrade performance or even crash when the system memory runs out.
In this paper, we propose AION, a comprehensive solution for handling late events in an efficient manner, implemented on top of Flink. In designing AION, we go beyond a naive solution that transfers state between memory and persistent storage on demand. In particular, we introduce a proactive caching scheme, where we leverage the semantics of stream processing to anticipate the need for bringing data to memory. Furthermore, we propose a predictive cleanup scheme to permanently discard window state based on the likelihood of receiving more late events, to prevent storage consumption from growing without bounds.
Our evaluation shows that AION is capable of maintaining sustainable levels of memory utilization while still preserving high throughput, low latency, and low staleness.


Calcium aluminate cement (CAC) has been explored as a sustainable alternative to Portland cement, the most widely used type of cement. However, the hydration reaction and mechanical properties of CAC can be influenced by various factors such as water content, Li2CO3 content, and age. Due to the complex interactions between the precursors in CAC, traditional analytical models have struggled to predict CAC binders' compressive strength and porosity accurately. To overcome this limitation, this study utilizes machine learning (ML) to predict the properties of CAC. The study begins by using thermodynamic simulations to determine the phase assemblages of CAC at different ages. The XGBoost model is then used to predict the compressive strength, porosity, and hydration products of CAC based on the mixture design and age. The XGBoost model is also used to evaluate the influence of input parameters on the compressive strength and porosity of CAC. Based on the results of this analysis, a closed-form analytical model is developed to predict the compressive strength and porosity of CAC accurately. Overall, the study demonstrates that ML can be effectively used to predict the properties of CAC binders, providing a valuable tool for researchers and practitioners in the field of cement science.


By analyzing convection characteristics and surface and basal heat flux we investigate the influence on mantle convection of finite thickness plates with dynamically determined velocities and mobile boundaries. Our 6 × 6 × 1 Cartesian geometry numerical model features periodic sidewall boundary conditions, a lower mantle that increases in viscosity and a Rayleigh number of 5 × 106 (based on the uniform viscosity upper mantle). A calculation with 9 plates and fixed plate boundaries is compared with a second calculation incorporating evolving plate boundaries. The number of plates in the latter case fluctuates between 6 and 9. We find that mean heat flux output decreases during periods characterized by the presence of larger plates and that evolving plate boundaries cause surface (and basal) heat flux output to vary much more than the heat flux observed with either fixed plate boundaries or a free‐slip surface.


The Morgan, Keenan, Kellman Atlas of Stellar Spectra appears to offer at the present time a highly consistent and satisfactory system of spectral classification. It is therefore of some interest to examine the spectra of the Atlas standard stars with both moderate and high dispersion in order to determine whether or not these stars show any anomalies not detectable on the lowdispersion spectra used for the Atlas observations. The present note reports some apparent spectral anomalies found in a few of the Atlas standard stars of types FV and GV. In Table I are listed all FV and GV Atlas standard stars that, so far as we know, are not spectroscopic or eclipsing binary systems, or variable stars. Among stars of the same spectral subtype


This paper is about Kiswahili and its role in the integration of the East African diverse communities. It is argued in this paper that there is an evolving social-cultural matrix unique to East Africa. This culture is finding its expression in Kiswahili, which is a popular lingua franca in the region. This lingua franca enjoys goodwill not just as a communication tool but also as a symbol of regional identity and integration of the East African peoples and cultures. Kiswahili's role as one of the inner agents of East Africa faces great challenges by the mere fact of globalization enforcing on the spread of major world languages like English, French, German, Spanish and others. Globalization is likely to spark off even more of the allegiance of the East African inhabitants to their native languages. All these factors, not withstanding Kiswahili's ability to reinforce the East African integration is extremely significant.


Prefetching is a well-known technique to mitigate scalability challenges in the Partitioned Global Address Space (PGAS) model. It has been studied as either an automated compiler optimization or a manual programmer optimization. Using the PGAS locality awareness, we define a hybrid tradeoff. Specifically, we introduce locality-aware productive prefetching support for PGAS. Our novel, user-driven approach strikes a balance between the ease-of-use of compiler-based automated prefetching and the high performance of the laborious manual prefetching. Our prototype implementation in Chapel shows that significant scalability and performance improvements can be achieved with minimal effort in common applications.


Adolescents show distress when their parents have conflicts. Their common reactions are fear, anxiety, anger and sadness. The main objective of the study was to investigate the effects of violence against women at home on the personality development of the adolescents. To get meaningful information both methods of quantitative and qualitative research were used. A cross-sectional research was conducted in all four urban towns of District Faisalabad, Punjab, Pakistan. A random sample of 400 adolescents and their mothers (25 from each union council) were taken through pre-designed interviewing schedule. In qualitative study detailed information through 8 focus group discussions of 4-12 mothers of the adolescents were collected. Uni-variate and bi-variate analysis demonstrates the connection among the variables. Results showed that the majority of those mothers who had a high level of violence in their home had high levels of bad effect on their adolescent's personality development.


We report an unusual case of acute suppurative thyroiditis associated with juvenile systemic lupus erythematosus (JSLE) onset. A 10 year-old girl presented with a painful voluminous swelling in the anterior cervical region with fever and dysphagia. She also had dysphonia, myalgia, swelling of the small joints of the hands, weight loss, and erythematous malar rash. Thyroid ultrasonography disclosed an ill-defined solid cystic area containing abundant echoes in suspension suggestive of an abscess in both lobes compatible with suppurative bacterial thyroiditis. Fine-needle aspiration biopsy showed a secretion with positive culture for Staphylococcus aureus. Endoscopic evaluation did not demonstrate pyriform sinus fistula. The child had no previous thyroid disease. Hormonal evaluation showed thyrotrophin (TSH) 13 microIU/ml and free thyroxine (FT4) 0.4 ng/dl. After laboratory confirmation of JSLE, high dose 'pulse' therapy was performed with methylprednisolone (30 mg/kg/day for 3 days), followed by prednisone (2 mg/kg/day). The acute thyroiditis was treated with oxacillin, metronidazole and amikacin which ameliorated the symptoms of infection followed by normalization of thyroid function with levothyroxine. In spite of the known association between autoimmune diseases and thyroid disorders, the coexistence of suppurative thyroiditis and JSLE is rare, generally occurring during the course of lupus and not at diagnosis.


The neural cell adhesion molecules (N-CAMs) are a group of structurally and immunologically related glycoproteins found in vertebrate neural tissues. Adult brain N-CAMs have apparent molecular weights of 180,000 and 140,000 with an additional form at 120,000 in murine brain. In embryonic brain, N-CAMs are represented by a highly sialylated form with an apparent molecular weight greater than 180,000. We have used monoclonal antibodies that cross-react with N-CAMs of various mammalian species to purify N-CAMs from adult murine and bovine brains and from embryonic murine brains. We determined the amino acid sequences of the amino-terminal domains of these molecules: Leu-Gln-Val-Asp-Ile-Val-Pro-Ser-Gln-Gly-Glu-Ile-Ser-Val-Gly-Glu-Ser. This sequence is highly conserved among all three forms of adult murine brain N-CAM as well as embryonic murine brain N-CAM and adult bovine brain N-CAM. Based on this sequence, we synthesized an undecapeptide and used it to raise a site-directed polyclonal antiserum. This antiserum reacted with the intact N-CAM in liquid phase radioimmunoassays, immunoblotting experiments, and immunofluorescent labeling of cells. The antiserum also reacted with N-CAMs in extracts of brain tissues from different species, confirming the highly conserved nature of the amino-terminal domain of mammalian N-CAMs. Immunofluorescence experiments indicated that this domain resides on the outer surfaces of cells that express N-CAMs, in both primary neuronal cell culture and in cell lines.


Aluminum-rich hierarchical MFI-type zeolites with high acidic-site density exhibit excellent activity and selectivity in bulky molecule-involved reactions. However, it is challenging to develop a facile and environmentally benign method for fabricating them. Herein, we employ a polymer that does not contain nitrogen and halogen elements to successfully synthesize aluminum-rich hierarchical ZSM-5 zeolite with a Si/Al ratio of 8 and a significant number of mesopores comprised of oriented-assembled nanocrystals. It is demonstrated that the nitrogen- and halogen-free polymer is instrumental in the formation of the ZSM-5 zeolite by serving as a template for constructing the hierarchical micro/mesoporous structure. Moreover, this polymer also acts as a crystal growth modifier to form a single-crystalline zeolite. Notably, the resultant zeolite shows a better catalytic performance in converting waste plastic into hydrocarbons than a commercial one. Our work enables the synthesis of high-quality hierarchical zeolites without requiring quaternary ammonium templates.


Context. Tens of light hydrides and small molecules have now been detected over several hundreds sight lines sampling the diffuse interstellar medium (ISM) in both the Solar neighbourhood and the inner Galactic disk. They provide unprecedented statistics on the first steps of chemistry in the diffuse gas. Aims. These new data confirm the limitations of the traditional chemical pathways driven by the UV photons and the cosmic rays (CR) and the need for additional energy sources, such as turbulent dissipation, to open highly endoenergetic formation routes. The goal of the present paper is to further investigate the link between specific species and the properties of the turbulent cascade in particular its space-time intermittency. Methods. We have analysed ten different atomic and molecular species in the framework of the updated model of turbulent dissipation regions (TDR). We study the influence on the abundances of these species of parameters specific to chemistry (density, UV field, and CR ionisation rate) and those linked to turbulence (the average turbulent dissipation rate, the dissipation timescale, and the ion neutral velocity drift in the regions of dissipation). Results. The most sensitive tracers of turbulent dissipation are the abundances of CH+ and SH+, and the column densities of the J = 3, 4, 5 rotational levels of H2 . The abundances of CO, HCO+, and the intensity of the 158 $\mu$m [CII] emission line are significantly enhanced by turbulent dissipation. The vast diversity of chemical pathways allows the independent determinations of free parameters never estimated before: an upper limit to the average turbulent dissipation rate, $\overline{\varepsilon}$ < 10$^{-23}$ erg cm$^{-3}$ s$^{-1}$ for $n_H$=20 cm$^{-3}$, from the CH+ abundance; an upper limit to the ion-neutral velocity drift, $u_{in}$ < 3.5 km s$^{-1}$, from the SH+ to CH+ abundance ratio; and a range of dissipation timescales, 100 < $\tau_V$ < 1000 yr, from the CO to HCO+ abundance ratio. For the first time, we reproduce the large abundances of CO observed on diffuse lines of sight, and we show that CO may be abundant even in regions with UV-shieldings as low as $5 \times 10^{-3}$ mag. The best range of parameters also reproduces the abundance ratios of OH, C2H, and H2O to HCO+ and are consistent with the known properties of the turbulent cascade in the Galactic diffuse ISM. Conclusions. Our results disclose an unexpected link between the dissipation of turbulence and the emergence of molecular richness in the diffuse ISM. Some species, such as CH+ or SH+, turn out to be unique tracers of the energy trail in the ISM. In spite of some degeneracy, the properties of the turbulent cascade, down to dissipation, can be captured through specific molecular abundances.


The frequency analysis of electroencephalographic (EEG) activity, either spontaneous or evoked by transcranial magnetic stimulation (TMS-EEG), is a powerful tool to investigate changes in brain activity and excitability following the administration of antiepileptic drugs (AEDs). However, a systematic evaluation of the effect of AEDs on spontaneous and TMS-induced brain oscillations has not yet been provided. We studied the effects of lamotrigine, levetiracetam, and of a novel potassium channel opener (XEN1101) on TMS-induced and spontaneous brain oscillations in a group of healthy volunteers. Levetiracetam suppressed TMS-induced theta, alpha and beta power, whereas lamotrigine increased TMS-induced alpha power. XEN1101 decreased TMS-induced delta, theta and beta power. Resting-state EEG showed a decrease of theta band power after lamotrigine intake. Levetiracetam increased theta, beta and gamma power, while XEN1101 produced an increase of delta, theta, beta and gamma power. Different AEDs induce specific patterns of power changes in spontaneous and TMS-induced brain oscillations. Spontaneous and TMS-induced cortical oscillations represent a powerful tool to characterize the effect of AEDs on in vivo brain activity. Spectral fingerprints of specific AEDs should be further investigated to provide robust and objective biomarkers of biological effect in human clinical trials.


Based on Edong Yangtze River Bridge, the second longest hybrid girder cable-stayed bridge with 926 meter long main span, the influencing factors and crucial techniques of the main span closure method for long span hybrid girder cable-stayed bridges are studied. According to theoretical analysis, numerical evaluation and practical test, the loading assistant closure method with better thermal adaptability and less influence on bridge line and the forced status is employed in Edong Yangtze River Bridge in order to meet the requirements of the unstressed state control method. Based on the mentioned advantages, the loading assistant closure method is applicable to long span hybrid girder cable-stayed bridges. The conclusion can provide a reference for the further design of similar bridges.


Abstract Background: Aortic root dilation has been observed in some patients with tetralogy of Fallot. This study examines whether 22q11.2 deletion is a risk factor for aortic root dilation in tetralogy of Fallot. Methods: Patients with tetralogy of Fallot, in the age group of 6–18 years, with defined deletion status and echocardiograms (2003–2009) were identified from research databases. The diameter at the aortic annulus, sinus, and sinotubular junction was measured and analysed as Z-scores. Variables were examined in univariate and multivariate regression analysis. Results: Of 171 patients, 66% were male, 16% had 22q11.2 deletion, 40% had an aortic arch anomaly, and 11% had both a 22q11.2 deletion and aortic arch anomaly. Echocardiograms were performed at a mean age of 12 + 3 years. More patients with 22q11.2 deletion had Z-scores >3 at the sinus diameter (45% versus 35%, p = 0.02). In the multivariate analysis, the combination of 22q11.2 deletion and aortic arch anomalies was associated with both aortic annular dilation (p = 0.006) and aortic sinus dilation (p = 0.05). In the subset with pulmonary valve atresia, similar findings were observed at the aortic annulus (Z-score of 4.6 versus 2.2, p = 0.05) and the sinuses (Z-score of 4.4 versus 2.7, p = 0.06). Male sex (p < 0.03) and pulmonary atresia (p < 0.006) were additional risk factors for dilation at the annulus and sinuses. Conclusions: Children with tetralogy of Fallot with 22q11.2 deletion and aortic arch anomalies have increased aortic annular and aortic sinus dilation. Further longitudinal study is needed to assess whether both features are associated with progressive aortic root dilation.


AIM
To ascertain the protective effect of oxyphenamone, a novel inodilator, against myocardial ischemia-reperfusion injury.

METHODS
A model of global myocardial ischemia-reperfusion injury (I-R) was established by arresting the infusion to heart 40 min followed by reperfusion 30 min in the preparations of rat Langendorff' s hearts. The protective effects of oxyphenamone were evaluated by the cardiac function, the activity of creatine phosphokinase (CPK) in coronary efflux, the myocardial energy metabolism and antioxidation, the membrane fluidity, the activity of ATPase, the calcium content and ultrastructure of mitochondria.

RESULTS
Administration of oxyphenamone to the infused heart before cardiac arrest and during reperfusion ameliorated the decreases of myocardial contractile force and coronary flow and the increase of the activity of CPK in coronary efflux induced by cardiac arrest-reperfusion (A-R). At the concentration of 1-10 micromol x L(-1) oxyphenamone dose-dependently antagonized the decrease of myocardial adenosine triphosphate (ATP) and creatine phosphate (PCr) induced by A-R, increased the activities of myocardial superoxide dismutase (SOD) and glutathione peroxidase (GSH-px), decreased mitochondrial malondialdehyde (MDA) content and increased membrane fluidity, glutathione (GSH) content and the activities of GSH-px and ATPase of mitochondria. The parameters mentioned above even maintained at normal level when high concentration of oxyphenamone (10 micromol x L(-1)) was applied. Oxyphenamone also antagonized the mitochondrial calcium overload and the ultrastructure damage of mitochondria induced by A-R obviously. Addition of oxyphenamone (1-100 micromol x L(-1)) to the system of Fe2+-cysteine or Fe2+-H2O2, which could produce oxygen free radicals, decreased MDA content and increased GSH and membrane fluidity of mitochondria significantly.

CONCLUSION
With the results of examinations of the cardiac physiological function, myocardial energy metabolism and antioxidation and the calcium content and ultrastructure of mitochondria, it is indicated that oxyphenamone could protect the isolated rat heart against cardiac arrest-reperfusion injury markedly and the mechanism of its action may be related to the antioxidative effect of this agent.


Abstract:Noise as an element evocative of teahouse atmosphere was part of the voice of opera in China at the turn of the twentieth century. As such, Chinese listeners embraced the talking machine wholeheartedly from the very beginning and reckoned with its musical force within the paradigm of high-class arts. We find an opposition in the early reception of the phonograph in the Western context in which concert-hall or opera-house performances encouraged the serious spirit of nineteenth-century musical romanticism.In this essay I list specific examples of teahouse theaters with phonographic musical accompaniment to early film. Such examples gleaned from newspapers do not appear consistently after the year 1910, suggesting that year may reasonably be considered a watershed in terms of the tentative endings of the symbiotic existence of phonographic music and live operatic performance. This special Chinese mindset paved the way for the gramophone to enter urban households as an "operatic singing machine." I contend that the Chinese listening habit cultivated in the boisterous acoustic environment of teahouse theaters had prepared the Chinese opera buff to focus on the meaningful operatic voice against the sonic backdrop of the "ambient" noise, an aesthetic experience similar to listening to early opera records.


Interesting practical uses of nonconducting poly( o -aminophenol) (POAP) films in the fields of bioelectrochemistry are discussed in this paper. Particular emphasis is given to the effects of applied potential, solution pH and interferents on the response current of biosensors based on POAP.


Wallenburg syndrome occurs due to damage to lateral segment of the medulla. Medial medullary syndrome occurs due to damage to upper portion of the medulla. I report a case of a 30 years old woman diagnosed with medullary syndrome [both medial & lateral features] in absence of CT scan findings sent to the department of Physiology for electrophysiological tests like nerve conduction studies, blink reflex, brainstem auditory evoked potential (BERA) & visual evoked potential (VEP). She had loss of sensations on the ipsilateral half of face (right), hemisensory loss on contralateral trunk & extremities, headache, contralateral hemiparesis (left), ipsilateral lingual paresis with atrophy, fibrillations with contralateral positive Babinski's sign. The electrophysiological tests showed decrease in conduction velocity of right facial nerve, left tibial & peroneal nerves with decreased amplitude. The nerve conduction studies of median nerve (both motor & sensory) were normal. In blink reflex, latency of R2 ipsilateral & R2 contralateral of supraorbital nerves were increased on right side. There were increased latencies of waves II, III, IV & V of BERA & increased P100 latencies in VEP. The results of the electrophysiological tests of the patient showed that she had features of both medial & lateral medullary syndrome suggesting a lesion of both upper & middle medulla. The CT scan in this case was normal but conduction of MRI & CT guided angiography of posterior cerebral & vertebral arteries could have further localized the lesion causing this mixed symptomology. Case Report Sharma; JAMMR, 32(15): 6-11, 2020; Article no.JAMMR.60717 7


Lethal removal by trapping is frequently the most cost- and time-effective means for managing wild pigs (Sus scrofa); however, the effectiveness of continuous-catch trap doors, which allow the entry of additional pigs into the trap after the door closes, remains unstudied. Our objective was to determine entry of wild pigs through closed root, saloon, and trainer continuous-catch doors. We constructed 26 corral traps on 4 study areas in east-central and southwest Alabama, USA, during the summer of 2011. We pre-baited each trap for ≥1 week to condition wild pigs to freely enter and exit traps and used game cameras to verify conditioning and to identify individuals and sounders. We then randomly assigned a trap door to each trap, set the trigger to capture only part of each sounder, and used game cameras to record the behavior of non-captured individuals. We observed 239 individuals from 24 sounders. Non-captured sounder members made 2.9 additional visits/trial (SE = 0.45) to traps after the door had closed, with each visit averaging 57.8 minutes (SE = 14.55) in duration. Of 222 opportunities (non-captured pigs observed after trap door had closed) only 9 (16%), 1 (1.9%), and 1 (0.9%) wild pigs entered through closed root, trainer, and saloon doors, respectively. Continuous-catch doors were ineffective at capturing substantial numbers of additional pigs after the door had closed. Given the comparatively greater expense of continuous-catch doors, landowners and wildlife managers should weigh the relative cost and benefits of these doors when developing wild pig removal programs. © 2013 The Wildlife Society


The finite element method (FEM) and the boundary element method (BEM) have entirely different characteristics. The FEM suits the analysis of a complicated region which includes nonlinear materials, and the BEM is useful for analyzing very large linear fields. This paper describes the hybrid finite and boundary element method which has the advantages of both methods. Here, we adopt the hybrid method for a 2D nonlinear magnetic problem with the moving boundary and make its advantages clear. >


The water transportation sector which includes ports and ships has a role in connecting one island with other islands so that the economic activities can run smoothly. Besides that, water transportation sector also has a contribution in supporting the economic growth in underdeveloped regions and being a supporting tool for the economy of developing regions. In other words, transportation has a contribution in triggering the dynamic in the development through the mobility of people, goods and services as well as supporting the national distribution pattern. PT. ASDP Indonesia Ferry (Persero) as a ferry port operator as well as roro ferry ships operator owns a port area to be turned into business extentions. Business in the field of port services provision is meant to bring benefits in order to enhance the value of the company by applying the principles of limited company. There are business fields that manage their businesses in both ships and ports.
The data used in this research includes primary data and secondary data. The primary data is received from questionnaire results and interviews with respondents. Meanwhile, the secondary data is received from the company in the form of data that matches the research. The determination of respondents is done using nonprobability sampling which uses convenience sampling technique. In this research, various kinds of data analysis are done which are Customer Satisfaction Index (CSI), Importance Performance Analysis (IPA) for the importance level according to passengers' perception and the level of performance and Cluster Analysis is used to reduce the data in the research into clusters and Benchmarking Analysis to compare the level of performance of the company's services with companies with better services.
In the results of the identification of the segmentation of the passengers of Merak Ferry Port, there are two segments which are the personal purposes segment and the work purposes segment. In this research, the level of satisfaction of all the passengers who undergo ferriage in Merak Ferry Port and use the ferries owned by ASDP is as much as 64.05%. A Customer Satisfaction Index value this high belongs to the satisfied category. The level of satisfaction of the passengers in the personal purposes segment whose reasons for ferriage are family matters and vacation purposes is as much as 65.19% and the level of satisfaction of the passengers in the work purposes segment whose reasons for ferriage are work purposes and business purposes is as much as 62.81%.
The perfect strategy to be applied in the business development of Merak Ferry Port and the ferries owned by ASDP in order to enhance the number of passengers who undergo ferriage is ensuring all the attributes in the main priorities are improved. Ensuring all the employees perform the standard operational procedure that has been made by the management party nicely so that the services provided to the passengers can give comfort, safety as well as enjoyment while undergoing ferriage using the ferries owned by ASDP.


This book offers translations of ten rhetorical declamations of the fourth-century AD sophist Libanius of Antioch and some related texts, almost all appearing for the first time in a modern language. In these works the declaimer impersonates such mythological or historical figures as Poseidon, Paris, Achilles, and Orestes, either in court (as prosecutor or defendant) or by trying to persuade his audience to take a course of action. The texts illustrate the sophist's eloquence and had an educational purpose in the schools, but were also delivered before adult audiences. They also put the Hellenic past on display for audiences of the Greek East in the Roman Empire. The annotated translations are accompanied by analyses of their themes, structure, and argumentation.


The extent to which severe acne affects patients' personality and emotional life is still undetermined. The patients with severe acne vulgaris frequently report feeling self-conscious, anxiety and social isolation. Isotretinoin is the drug indicated for severe, recalcitrant nodular acne that has proved unresponsive to other therapies. Isotretinoin's link to psychiatric adverse events is controversial. For the last 15 years there has been debate over whether isotretinoin could be causing depression and subsequent suicide in teenagers. Though depression and suicide are important health problems for teenagers, there is as yet no good evidence that isotretinoin contributes significantly to either. Numerous clinical investigations have failed to identify an association between the use of the isotretinoin and the development of psychiatric disorders. The causal relationship between isotretinoin therapy and depression has not been clearly established and needs further study. Acne may be associated with low self-esteem and poor self-image, problems which can eventually lead to serious psychological conditions. Since isotretinoin is an effective treatment for acne, it may help reduce associated psychological disturbances. The goal of this study was to investigate the influence of isotretinoin on psychological status of acne patients during and after treatment. The following work describes the benefit of using a questionnaire as a clinical tool to identify acne patients who have developed psyhological sequelae as a result of the disease process. A sample of 50 patients (23 man and 27 women) with moderate to severe form of acne vulgaris were prospectively examined for psychological, emotional and dermatological symptomatology using a variety of standardised psychometric inventory such as DSQL, APSEA, BDI, MPS, STAI which were applied at the beginning of the therapy, as well as after 5, 10, 16 weeks and at the end of the treatment when the disease had been brought under control effectively. The subgroup of 25 patients (15 man and 10 women) has received isotretinoin taking in consideration the severe, recalcitrant form of papulopustular or nodulocystic acne. The results of this prospective clinical study show significant decrease of depression and anxiety as well as an improvement of psychosocial status and quality of life after succesful treatment in both groups of patients. The use of oral isotretinoin was very effective therapy and no influence on psychological disturbances was observed. However, monitoring patients for depression, depressive symptoms, and suicidal ideation can help identify those who may be at risk and improve patient care by facilitating appropriate diagnosis and treatment of patients experiencing clinical depression.


: Expression of fibronectin (Fn) during eye tissue regeneration in the newt after retinal detachment and lens removal was studied by immunohistochemistry. Proliferation of cells involved in eye tissue regeneration was studied using autoradiography. Fn was detected around the cell membranes of undifferentiated proliferating and migrating cells in ciliary body of the iris and growth zone of the retina. Redistribution of Fn was observed in proliferating cells of the dorsal iris participating in lens regeneration. Fn appeared on the apical surface of proliferating redifferentiating pigment epithelium (PE) cells at the periphery of the eye and over the whole surface of proliferating PE cells in the central part of the eye. The Fn level in the Bruch's membrane decreased in the area of transdifferentiating cells detachment from PE layer (in the lower part of the eye) but continued to be stable in the area of PE cell redifferentiation (at the periphery of the eye). The role of Fn is discussed in relation to transdifferentiation, proliferation and migration of cells in the regenerating eye.


Contractual arrangements of different types have increasingly found in West Sumatera not only in subsistence and commercial crops but particularly also in livestock sector.  Contract farming in livestock agribusiness is generally defined as broiler farms under an agreement between farmers and a livestock inputs supplier. Within this broad definition, there are different variants of contracts depending on the formality and intensity of contractual arrangement. This study objective was to prove that the design of a contract, as representation of vertical integration intensity in broiler agribusiness, has different efficiency effects on production.  The stochastic frontier production function was used in this study, and employed a regression method to estimate the level of technical efficiency.  Data were collected from 87 broiler fattening farms consisted of 50 broiler fattening farms under formal contractual system and 37 broiler fattening farms under informal contractual system. The results showed that farm experience and improvement of the contract system would reduce the level of technical inefficiency of broiler farms. The study concluded that broiler farms under formal and detail contract farming had greater technical efficiencies compared to broiler farms under informal unwritten contract arrangement.  However, the broiler farms under informal contract obtained higher net returns compared to the broiler farms under formal contract arrangement.


This study aims to examine the effect of profitability, growth opportunities, debt covenant, political cost and capital intensity on accounting conservatism. The population is 177 manufacturing companies listed on the Indonesia Stock Exchange with a total sample of 125 companies. The sampling technique uses purposive sampling method. The type of data in this study is secondary data obtained from annual financial statements. The form of research used is associative research. The analysis technique used is descriptive statistical analysis, classic assumption test, multiple linear regression analysis, coefficient of determination and hypothesis testing using data processing aids in the form of Statistical Product and Service Solutions (SPSS) version 22. The test results show that profitability and growth opportunities negative effect on accounting conservatism. Political cost has a positive effect on accounting conservatism. Debt covenant and capital intensity do not affect accounting conservatism. Keywords : profitability, growth opportunities, debt covenants, political costs, capital intensity and accounting conservatism.


The Southern Photometric Local Universe Survey (S-PLUS) is imaging ∼9300 deg2 of the celestial sphere in 12 optical bands using a dedicated 0.8 m robotic telescope, the T80-South, at the Cerro Tololo Inter-american Observatory, Chile. The telescope is equipped with a 9.2k × 9.2k e2v detector with 10 $\rm {\mu m}$ pixels, resulting in a field of view of 2 deg2 with a plate scale of 0.55 arcsec pixel−1. The survey consists of four main subfields, which include two non-contiguous fields at high Galactic latitudes (|b| > 30°, 8000 deg2) and two areas of the Galactic Disc and Bulge (for an additional 1300 deg2). S-PLUS uses the Javalambre 12-band magnitude system, which includes the 5 ugriz broad-band filters and 7 narrow-band filters centred on prominent stellar spectral features: the Balmer jump/[OII], Ca H + K, H δ, G band, Mg b triplet, H α, and the Ca triplet. S-PLUS delivers accurate photometric redshifts (δz/(1 + z) = 0.02 or better) for galaxies with r < 19.7 AB mag and z < 0.4, thus producing a 3D map of the local Universe over a volume of more than $1\, (\mathrm{Gpc}/h)^3$. The final S-PLUS catalogue will also enable the study of star formation and stellar populations in and around the Milky Way and nearby galaxies, as well as searches for quasars, variable sources, and low-metallicity stars. In this paper we introduce the main characteristics of the survey, illustrated with science verification data highlighting the unique capabilities of S-PLUS. We also present the first public data release of ∼336 deg2 of the Stripe 82 area, in 12 bands, to a limiting magnitude of r = 21, available at datalab.noao.edu/splus.


Potential of marine fisheries in our country is very big, one of them in Indramayu. However, the people who tend to still use the traditional way of making or repairing boats resulted in utilization is not optimal. Karangsong fundamental problem is the inability of traditional fishing boats as a means of providing the arrest. An alternative form of boat made of fiberglass are very worthy to be a technological solution. Fiberglass technology has long been known, but its use by fishermen in the village of Indramayu especially Karangsong not optimal. Therefore, the need for training on the application of fiberglass technology. The program is expected to make the fishing communities get added value and simplify the process of making a boat that is necessary to improve the productivity of the fishermen. The method is performed in the implementation of this program for surveying, socialization programs to the community in the village Karangsong, preparation tools and place, giving General knowledge of fiberglass materials, training design boat design, the development of the use of resin, boat making, evaluation and monitoring. Result of this activity is increased knowledge about fiberglass fishing communities around and start applying fiberglass technology for repair and manufacture of traditional boats.


What are the legal rights to ancient documents of editors, archaeologists, curators, or modern states? In the light of recent controversies, this collection emphasizes the status of the Dead Sea Scrolls. The Dead Sea Scrolls were found in Palestine, recovered in Jordan, and largely edited by an international Christian team who prevented public access to unpublished manuscripts. Subsquently, the state of Israel, which had already purchased many of the Scrolls, has assumed responsibility for all of them. Most recently, one scroll editor has claimed copyright on his reconstruction, instigating a lawsuit and introducing serious implications for future Scrolls scholarship. This volume looks at international copyright and property rights as they affect archaeologists, editors and curators, but focuses on the issue of 'authorship' of the Scrolls, both published and unpublished, and the contributors include legal experts as well as many of the major figures in recent controversies, such as Hershel Shanks, John Strugnell, Geza Vermes and Emanuel Tov.


A well-known limitation in pretrain-finetune paradigm lies in its inflexibility caused by the one-size-fits-all vocabulary.This potentially weakens the effect when applying pretrained models into natural language generation (NLG) tasks, especially for the subword distributions between upstream and downstream tasks with significant discrepancy. Towards approaching this problem, we extend the vanilla pretrain-finetune pipeline with an extra embedding transfer step. Specifically, a plug-and-play embedding generator is introduced to produce the representation of any input token, according to pre-trained embeddings of its morphologically similar ones.Thus, embeddings of mismatch tokens in downstream tasks can also be efficiently initialized.We conduct experiments on a variety of NLG tasks under the pretrain-finetune fashion. Experimental results and extensive analyses show that the proposed strategy offers us opportunities to feel free to transfer the vocabulary, leading to more efficient and better performed downstream NLG models.


Tax is an alternative method for a country to obtain revenue for spending. But the issue arises when there are differences of opinion on the tax rate. Economists argue that to obtain higher tax revenue, it is necessary to lower the tax rate. In this paper, an analysis of tax rates is conducted by looking at the findings of Ibn Khaldun in his book Muqaddimah. This study also examines other hypotheses related to taxation. The findings show that the optimal rate of taxation can be determined. Keyword: optimal tax rate, tax revenue, Khaldunia, tax-spending hypothesis, fiscal


Structured Modeling is a common modeling method. Modeling analysis in Structured Modeling is complex, difficult and time-consuming. This paper proposed the service architecture under Grid analysis environment for SM that is ideally suited to Semantic Web applications. Based on WSDL, OWL-S, FIPA, and OGSA, extending existing Grid paradigms to harness emerging Web service technologies such as SOAP, WSDL and BPEL, a concise overview of Grid middleware for SM is provided. The functionality model, the Web service-based grid architecture for SM, and the logic function architecture of SM is proposed by this paper.


Balance beam, a controller that is built adopting the gyro effect, can freely control the attitude of an unstructured object by means of the position controlling of an inner gimbal. However in the former research, the weight (inertia) of a load should be known to issue a proper command for the gimbal, which makes it hard to operate the balance beam in field applications because the load can be changed frequently and, moreover, the inertia of the same load could be different according to how the load is held. Therefore an accident could be caused by the operation with an improper gimbal command. One of the possible approaches to solve the problem is to give a balance beam controller an ability to detect the inertia of a load so that it can limit the velocity of the load ordered by a user. In this paper, we designed a controller that can estimate the inertia of the load based on the result we did before; the fact that when there is smaller inertia of load, the larger amount of the restoration displacement occurs. Thus, the load could be identified by issuing a predefined command to measure the amount of the restoration displacement, which makes us able to construct the controller that can limit the angular velocity of the load by planning the motion. Experimental results show the performance of the controller with some loads.