BACKGROUND
Multiple organ damage has been observed in patients with COVID-19, but the exact pathway is not known. Vital organs of the human body may get affected after replication of SARS-CoV-2, including the lungs, heart, kidneys, liver and brain. It triggers severe inflammation and impairs the function of two or more organ systems. Ischaemia-reperfusion (IR) injury is a phenomenon that can have disastrous effects on the human body.

METHODS
In this study, we analysed the laboratory data of 7052 hospitalised patients with COVID-19 including lactate dehydrogenase (LDH). A total of 66.4% patients were men and 33.6% were women, which indicated gender difference as a prominent factor to be considered.

RESULTS
Our data showed high levels of inflammation and elevated markers of tissue injury from multiple organs C reactive protein, white blood cell count, alanine transaminase, aspartate aminotransferase and LDH. The number of red blood cells, haemoglobin concentration and haematocrit were lower than normal which indicated a reduction in oxygen supply and anaemia.

CONCLUSION
On the basis of these results, we proposed a model linking IR injury to multiple organ damage by SARS-CoV-2. COVID-19 may cause a reduction in oxygen towards an organ, which leads to IR injury.


It has been generally accepted that crystal shrinkage during Ostwald ripening can be understood simply as a reverse process of crystal growth, and as a result, little attention has been paid to shrinkage behavior. The entire microstructure of polycrystalline materials, however, forms as a consequence of both growing and shrinking crystals. Thus, scrutiny of shrinking characteristics in addition to growth aspects is essential for a complete understanding of the evolution of microstructure during Ostwald ripening. By capturing real-time in situ high-resolution electron micrographs at high temperature, we herein demonstrate the shrinkage behavior of nanocrystals embedded in a solid crystalline matrix during the ripening process of a metal phosphate. Unlike typical crystal growth behavior based on two-dimensional homogeneous nucleation, heterogeneous types of nucleation with nanoscale pits at solid-solid interfaces (or crystal edges) are observed to dominantly occur during shrinkage of the crystals. The findings of this study suggest that crystal shrinkage proceeds with a lower activation energy barrier than that of crystal growth, although both crystal growth and shrinkage take place at the same time during Ostwald ripening.


Introduction. Genetic prion diseases, such as Creutzfeldt-Jakob disease (CJD), Gerstmann-Straussler-Scheinker disease (GSS), Fatal Familial Insomnia (FFI), are associated with the mutations of prion (PRNP) gene. More than 30 pathogenic PRNP mutations were identified. Since Alzheimer disease (AD) and prion diseases have many similarities in the neuropathological and physiological symptoms, we tested 89 Korean patients with different neurodegenerative disorders, AD, CJD, Parkinson disease (PD), Mild cognitive impairment (MCI) and Frontotemporal dementia (FTD), for prion mutations. Materials and Methods. In total, 89 dementia patients under 60 y of age were screened for prion mutation, 45 AD patients, 8 FTD patients, 1 PD patients, 15 MCI patients, 11 patients with subjective memory impairment, 3 patients with vascular cognitive impairment, 1 CJD patients, 3 normal person (kin to the dementia patient), 1 patients with transient global amnesia and 1 patient with Hashimoto encephalopathy. The coding region (exon2) of PRNP gene was amplified by PCR, and PCR products were purified by specific kit. Both of the 5′ and 3′ bands of the PCR amplicons were sequenced. Results. We detected three pathogenic prion mutations among 89 dementia patients. Glu200Lys was found in two patients, whom were clinically diagnosed as AD previously. Met232Arg was detected in four patients, where 2 among 4 were clinically diagnosed as MCI patients, one with AD patient and one with normal individual. Val180Ile was also reported in one clinically diagnosed AD patient. Conclusion. Both Met232Arg and Val180Ile are associated with familial or sporadic CJD in Korea and Japan. Met232Arg might be involved in other kind of dementia too, because it was described in a Japanese patient with Dementia with Lewy bodies (DLB). Val180Ile was found in a CJD patient with Alzheimer type pathology in Japan. The effects of prion mutations seem to be heterogeneous. Hence, it might be possible that PRNP could be a potential risk factor for AD. There is another option that these patients might be CJD patients. Our findings suggest that genetic analysis could improve the differential diagnosis of dementia and the genetic testing for prion mutations should be important for dementia patients.


This study reports the influence of physico-chemical factors on the swell/collapse characteristics of laboratory-prepared dry silty clay specimens. Also, a comparison of the physico-chemical behavior of dry and saturated silty clay specimens is made in light of an earlier proposed concept for saturated clays. Dry sodium-rich/calcium-rich silty clay specimens were wetted with tap water, 0.4 N sodium chloride, and 0.4 N calcium chloride solutions in the double odometer tests. The compression behavior of the saturated silty clay specimens was dominated by the physico-chemical effects at all the experimental pressures. Comparatively, the physico-chemical effects dominated the volume change behavior of the dry silty clay specimens on wetting only at the lower stresses, whereas the mechanical effects prevailed at the higher stresses.


recent development of social democracy in Britain, France, Italy, West Germany, and the Scandinavian countries, but looks also at a wider range of smallcr socialist parties. A compact introduction examines the nature of social democracy today and stresses the variety of its forms: '... thc social democratic parties have neither a distinctivc and shared ideology nor a common and unique organizational pattern' (p. x). After discussing the historical evolution of the European socialist parties, the opening chapters examine the interaction of Social Democracy and Communism. There is brief mention of the social democratic tradition in Central and Eastern Europe. Chapter 3 ('Dimensions of Party Support') discusses the relationship between social democratic parties and the trade unions and the Churches. Demographic and other aspects of electoral support and party membership are also analysed here. C'haptcr 4 considers doctrinal revision ; the authors discuss the increased political involvement of young people during the r g6os. The ensuing chapter is concerned with foreign policy, taking in decolonization and the


Riedel's thyroiditis is a rare fibro‐inflammatory process originating in the thyroid gland with progressive extension and invasion of surrounding tissues. Patients frequently present with a stony hard thyroid mass suggestive of anaplastic carcinoma. We report a striking case of Riedel's thyroiditis associated with hypothyroidism, hypoparathyroidism and bilateral vocal cord paralysis. A dramatic response to high dose prednisone and levothyroxine therapy was seen, with recovery of parathyroid and vocal cord function. Our case suggests that early initiation of combination therapy may be important, particularly in the presence of severe disease.


Cylindrical Li-ion batteries (cells) typically have safety vents in the positive terminal to enable the release of gases that build up inside the battery and thus help reduce the effects of thermal runaway, including fire and explosion. However, the vents are not always effective, and it is critical to understand why. This paper overviews various vent designs and presents two case studies of vents in cylindrical Li-ion batteries that failed to operate properly. The first case study concerns a Sony VCT5 18650 Li-ion battery in which thermal runaway caused the cylindrical casing (can) to rupture. The second case study involves an Ampking 20700 Li-ion battery in which thermal runaway caused side-wall rupture of the casing. In both cases, the vents did not function as intended. Computed tomography (CT) scanning was used to investigate the internal structure of the battery to assess the failure mechanisms of the failed vents. These cases raise concerns about the efficiency, reliability, and safety of some current vent designs.


New Ir-NHC complexes based on different heterocyclic moieties like imidazole, benzimidazole and imidazolidine are presented and tested in transfer hydrogenation catalysis. A broad range of steric and electronic properties of NHC ligands is covered to give an idea for catalyst design from the experimental point of view.


When modeling a nonequilibrium economy, the behavior of participants is described by the same optimization problems, including the criterion and internal technological and budgetary constraints, as in the theory of Walrasian equilibrium. They are only supplemented by external restrictions on the purchase (or sale) of scarce (slow-moving) products. Various principles are known for establishing these boundaries. They can be fixed (a rigid scheme of rationing) and not depend directly on the decisions of the participant, or be determined by the demand expressed by them (flexible scheme). The presented demand for rationable products, as a rule, does not coincide with the Walrasian one. We will call it an order. In well-known models, the order is considered equal to active demand. The concept of active demand has been successfully used in price control models. However, it is not the object of the choice of participants aimed at optimizing their criteria. Meanwhile, it seems natural that manufacturers and consumers, seeking to maximize utility, are free to choose order sizes at their own discretion. Modeling of the situation arising with this approach is the goal of the present work and is based on a modification of the rationing scheme proposed by J.P. Benassi The work also considers equilibrium models at fixed prices, in which participants, when forming demand, take into account the scarcity of products and the level of satisfaction of orders. Models are used to assess the impact of taxes, government spending, and other macro-regulators on employment and national income. The paper provides an overview of literary sources in the subject area, as well as an economic interpretation of the results.


Background
The general population's understanding of musculoskeletal health is likely influenced by media reports of the ailments of prominent athletes. We assessed factors independently associated with debatable or potentially misleading medical statements in mainstream sports media coverage of the ailments of professional and college athletes.

Methods
We identified and assessed 200 Internet media reports of musculoskeletal ailments of prominent athletes between February 19th and March 26th, 2018. We recorded medical statements about mechanism, diagnosis, treatment, and prognosis. We then classified those statements as accurate, debatable, or possibly misleading. We created a multivariable logistic regression model to identify factors independently associated with debatable or possibly misleading statements.

Results
Forty-five percent of statements were debatable or possibly misleading. Statements about diagnosis (Odds Ratio [OR]=0.17; P< 0.001), treatment (OR=0.33; P=0.007), or prognosis (OR=0.27; P=0.003) and statements about shoulder and elbow ailments were more likely to be inaccurate compared to statements about mechanism and statements about knee ailments (OR=3.3; P=0.04) respectively.

Conclusion
Coverage of sports ailments in the mainstream media are a common source of misinformation. Ailments of prominent athletes may represent a useful opportunity to teach people about musculoskeletal health.


The Article briefly discusses the need for generation of the Science of Ahangyol, and this science's scientific basis, object and subject, category system, scientific research methods and application options. Ahangyol is a universal science and may be useful in any sphere. It may assist in problem solving in peacemaking process and in many areas such as ecology, economics, politics, culture, management and etc. This science stipulates that any activity and any decision made in the life may only and solely be successful when they comply with harmony principles more, which are the principles of existence and activity of the world. A right strategic approach of the Eastern Philosophy and the Middle Age Islamic Philosophy and scientific thought has an important potential. This strategic approach creates opportunities to also consider irrational factors in addition to rational ones comprehensively in scientific researches. The modern scientific thought contributes to implementation of these opportunities. Ahangyol is a science of determination of ways to achieve harmony in any sphere and of creation of special methods to make progress in these ways through assistance of the modern science. Methods of the System Theory, Mathematics, IT, Astronomy, Physics, Biology, Sociology, Statistics and etc. are more extensively applied. Information is given on some of these methods. Moreover, the Science of Ahangyol, which is a new philosophical worldview and a new paradigm contributes to clarification of metaphysic views considerably and discovery of the scientific potential of religious books.


On 11 June 2009, the Office of Fair Trading ("OFT") announced that it had decided to refer the proposed merger of Ticketmaster Entertainment Inc ("Ticketmaster") and Live Nation Inc ("Live…


Background The ARFI method is a new tool to evaluate the stiffness of soft tissues which is is wellknown for evaluating the stiffness of liver parenchyma. No studies have been done concerning the salivary glands parenchyma. Objectives The aim of this study was to evaluate the ARFI method as a new tool to assess the stiffness of major salivary glands tissue. For this, we studied: 1. ARFI system in major salivary glands in healthy population depending on age and sex. 2. The intra and inter-observer reliability of ARFI quantification in major salivary glands in this population. Methods We prospectively studied 30 healthy adults without known salivary pathology. We divided the population in 3 sub groups of age (15-30, 31-45, and 46-60 years old). ARFI quantification, given as shear waves velocity (SWV) of the 2 parotid and 2 sub-mandibular glands was performed by two observers (A.G, S.J.J). We used a SIEMENS S2000 machine with a linear probe (10-12.5 MHz frequency). We assessed the 2 parotids glands in a longitudinal scan and the 2 submandibular glands in a longitudinal scan. We realised 10 pulses for each glands. 5 pulses were done in the central part of the gland and the 5 others pulses were done in a superficial part. For statistical analysis, we calculated the average measures of the 10 pulses of each gland for each ultrasonographists. For reliability, we evaluated the intra class coefficient correlation. Results The average parotid and sub-mandibular SWV were in m/sec 1.9 and 1.99 for men (n=15) and 1.78 and 1.77 for women (n=15), respectively. Parotid and sub-mandibular glands SWV were 1.81 and 1.78 for the 15-30 years old, 1.79 and 1.95 for the 30-45 years old and 1.93 and 1.9 for the 45-60 years old, respectively. Inter-observer agreement, expressed as intraclass correlation coefficient was not so good for the parotid and good for the sub-mandibular. Intra-observer agreement was respectively for observer A and B, 0,613 and 0,201 for the parotid and 0,725 and 0,594 for the sub-mandibular glands. Conclusions ARFI method in salivary glands do not seem significantly different depending on age and sex in a healthy population. However, at this time, ARFI quantification needs to obtain a good reliability to be used in practice and to be evaluated in a population of primary GougerotSjögren Syndrome. References Sporea I, Sirli R, Bota S, Vlad M, Popescu A, Zosin I. ARFI elastography for the evaluation of diffuse thyroid gland pathology: Preliminary results. World J Radiol. 2012 Apr 28;4(4):174-8. Acknowledgements The team of radiology department and the team of Ultrasound Unit department from Brest, FRANCE Disclosure of Interest None declared DOI 10.1136/annrheumdis-2014-eular.4182


In 15 patients with congenital adrenal hyperplasia, the corticotrophic and melanotrophic functions were evaluated by plasma ACTH and beta-MSH radioimmunoassay. Evaluation of the corticotrophic and melanotrophic functions was also performed in 3 subjects after provocative tests (insulin-induced hypoglycaemia, metyrapone) and in 5 subjects after infusion of synthetic MIF (MSH-release inhibiting factor). The results indicate a significant increase in plasma ACTH and beta-MSH in CAH. In addition, we found that although in most cases there was a significant positive correlation between the plasma ACTH and beta-MSH levels, in some only the plasma ACTH values were high and beta-MSH values normal. No other anomalies of the corticotrophic and melanotrophic functions occurred in CAH as shown by the results of the provcative tests. Lastly, it must be emphasized that no modifications of plasma beta-MSH after synthetic MIF infusion were found in subject with normal or high plasma beta-MSH. These findings induce us to consider it unlikely that synthetic MIF is active in man.


A model of optically pumped NMR (OPNMR) behavior in GaAs that connects the photon energy dependence of the OPNMR signal intensity for (69)Ga with different polarizations of light has been developed. Inputs to this model include experimental conditions--external magnetic field (B(0)), temperature (T), and optical pumping parameters (tau(L), laser helicity)--as well as parameters that arise from sample-specific characteristics--electron spin lifetime (T(1e)), electron lifetime (tau(e)), electron-nuclear correlation time (tau(c)), and sample thickness (z). These various inputs affect the profile of the OPNMR signal intensity as a function of photon energy (E) in a predictable manner. Therefore, the profile can serve as a composite fingerprint by which individual parameters can be inferred when not known. Characteristics of the profile include the photon energy for maximum OPNMR signal intensity and the intensity ratio between sigma(+) and sigma(-) light.


OBJECTIVE
To examine the bromodeoxyuridine (BrdU) incorporation into DNA of thyroid follicular cells (TFC) in the remaining thyroid lobe after hemithyroidectomy (hemiTx) in 1, 2, 3 and 4 weeks time after surgery.

METHODS
The experiment was performed on male Wistar rats. The Cell Proliferation Kit (Amersham, UK) was used in order to detect the incorporated BrdU. The BrdU incorporation was expressed as a BrdU labeling index (BrdULI; a number of BrdU-immunopositive TFC per 1000 TFC).

RESULTS
1. No statistically significant changes of BrdULI were observed between the particular groups of sham-operated (shamTx)-rats in 1, 2, 3 and 4 weeks time after surgery, and in comparison of each of them to the controls (at time "0"); 2. In the first 2-week period after hemiTx, an increasing effect of that surgical procedure on BrdULI value was observed (the highest BrdULI value was detected 2 weeks after hemiTx); 3. In the third and fourth week after hemiTx, a decrease of BrdULI value was observed, as compared to BrdULI groups (in 1- and 2-week time after hemiTx), and to the controls (at time "0"); 4. An increase of weight of contralateral lobe was shown in 1, 2, 3 and 4 weeks after hemiTx in comparison to thyroid lobe weight in intact rats.

CONCLUSIONS
During the first 2 weeks after hemiTx, the thyroid growth in the remaining thyroid lobe seems to ensue by hyperplasia mechanisms. The thyroid growth processes during subsequent 2 weeks (3rd and 4th) could result from other mechanisms - for example, from hypertrophy.


This study focuses on the localization using Received Signal Strength (RSS) in dense multipath indoor environments. A dynamic system approach is proposed in the fingerprinting module, where the location is estimated from the state instead from RSS directly. The state is reconstructed from a temporal sequence of RSS samples by incorporating a proper memory structure based on Taken's embedded theory. Then, a more accurate state-location correlation is estimated because the impact of the temporal variation due to multipath is considered. An indoor experiment in Wireless Local Area Networks (WLAN) shows the effectiveness of our approach.


Visceral artery aneurysms represent a very rare condition. The affected patients usually present as emergency secondary to the sudden rupture of the aneurysm or as an incidental finding on imaging. In this setting, gastric and gastroepiploic aneurysms account for only about 4% of all the splancnic aneurysms. Since ruptured visceral aneurysms present a high mortality, a prompt and adequate (surgical or radiological interventional) treatment is mandatory. Due to the difficulty in achieving an adequate transcatheter access in some cases the emergency laparotomy may represent the only chance for the recover of the affected patients. We report two cases of ruptured left gastroepiploic aneurysms occurred in two young male patients, treated respectively with emergency laparotomy and laparoscopy.


Researchers have debated whether entrepreneurial opportunities are discovered or created. However, they have often overlooked the importance of the contextual variables that stimulate, shape, and define the entrepreneurial act. This article focuses on entrepreneurial activities within technology-based established companies and shows how and why certain contexts are more conducive for discovery, while others promote the discovery and creation of opportunities. The article suggests a virtuous and dynamic cycle where discovery enriches creation which, in turn, fosters the discovery of new opportunities. The focus on the context and key features of entrepreneurial search contributes to the behavioral theory of and the debate on the origins of opportunities. Copyright © 2008 Strategic Management Society.


A new molecular-dynamics method at constant pressure has been proposed. As the three edge vectors of a crystal cell as well as the position vectors of all particles are taken as independent variables, this method allows the crystal to relax fully. Furthermore, the effect of pressure on the crystal structure is explicitly given in this approach. As an example, the evolution process of cobalt from a structure far from the final one to the ideal hexagonal close packing structure was given.


The authors have developed a simple highly accurate method for measuring antibiotic concentrations in liquid media of the eye. It is based on the ability of antibacterial drugs to diffuse in agar medium. The studies may be carried out at any bacteriologic laboratory.


Natural products and synthetic compounds are a valuable source of new small molecules leading to novel drugs to cure diseases. However identifying new biologically active small molecules is still a challenge. In this paper, we introduce a new activity prediction approach using Bayesian belief network for classification (BBNC). The roots of the network are the fragments composing a compound. The leaves are, on one side, the activities to predict and, on another side, the unknown compound. The activities are represented by sets of known compounds, and sets of inactive compounds are also used. We calculated a similarity between an unknown compound and each activity class. The more similar activity is assigned to the unknown compound. We applied this new approach on eight well-known data sets extracted from the literature and compared its performance to three classical machine learning algorithms. Experiments showed that BBNC provides interesting prediction rates (from 79% accuracy for high diverse data sets to 99% for low diverse ones) with a short time calculation. Experiments also showed that BBNC is particularly effective for homogeneous data sets but has been found to perform less well with structurally heterogeneous sets. However, it is important to stress that we believe that using several approaches whenever possible for activity prediction can often give a broader understanding of the data than using only one approach alone. Thus, BBNC is a useful addition to the computational chemist's toolbox.


Berenil, which is known to inhibit synthesis of nucleic acid, DNA and RNA, and polyamine, induced gametocytogenesis in cultured Plasmodium falciparum, although the mechanism by which Berenil induces gametocytogenesis is unknown. Asexual parasites of a strain of P. falciparum that seldom produce gametocytes in in vitro culture began gametocytogenesis after 2-24 hr treatment with RPMI 1640 medium containing Berenil (final concentration, 0.1-10.0 micrograms/ml) with horse serum. Gametocytogenesis was consistently observed from 3 days after the addition of Berenil to culture. After parasites were cultivated in RPMI 1640 medium containing Berenil (final concentration, 3.0-10.0 micrograms/ml) and concanavalin A with horse serum for 2 hr, Berenil and concanavalin A were removed from culture medium by centrifugation. Nevertheless, induction of gametocytogenesis was observed. The addition of concanavalin A (final concentration, 10 micrograms/ml) to RPMI 1640 medium containing Berenil enhanced the induction of gametocytogenesis by Berenil. However, when RPMI 1640 medium with concanavalin A was used without the addition of Berenil, no gametocytogenesis was observed as in RPMI 1640 medium alone.


In this paper, we argue that by carefully considering spatial reusability of the wireless communication media, we can tremendously improve the end-to-end throughput in multi-hop wireless networks. To support our argument, we propose spatial reusability-aware single-path routing (SASR) and anypath routing (SAAR) protocols, and compare them with existing single-path routing and anypath routing protocols, respectively. Our evaluation results show that our protocols significantly improve the end-to-end throughput compared with existing protocols. Specifically, for single-path routing, the throughput gain is up to 2.9× for anypath routing, the throughput gain is up to 62.7%.


This paper considers the basic problem of transmitting digital information through a noisy channel with minimum probability of error in finite time. The transmitted signals are average-power limited, and the noise is assumed to be additive Gaussian with a power spectrum which may be nonwhite. A theory of so-called efficient codes (minimax, equal separation, and nearly equal separation) is developed. Efficient codes are formed from weighted sums of eigenfunctions generated by an integral equation with its kernel corresponding to the inverse Fourier transform of the Gaussian noise power spectrum. In addition, the theory of equidistant and nearly equidistant codes [1] is extended to the case of nonwhite Gaussian noise. It is shown that efficient codes perform better than equidistant codes if the noise is nonwhite; i.e., properly chosen waveforms are more efficient than binary coding. Performance results are given for several different codes when the interference is white Gaussian noise and when the noise power density increases with increasing frequency. The detection scheme used does not require estimation of the signal or the noise levels at the receiver and is thus independent of fading.


Contrary to Durkheim's proposition about suicide during wartime, the Netherlands had high suicide rates in 1940 and 1945. Earlier research showed that the high rate for 1940 could be ascribed to suicide among Jews. That finding concurred with another Durkheimian hypothesis, saying that people who expect to be excluded from society are more likely to commit suicide. In this article we employ the same proposition to explain the high rate for 1945. Assuming that members of the Dutch National-Socialist Movement expected punishment after World War II, we re-analyzed the counting cards preserved at Statistics Netherlands, and found 113 suicides for the period 1944-1947 by members of the Dutch National-Socialist Movement. Our explanation received additional support by the finding that five political suicides occurred in September 1944, when the Southern part of the Netherlands was liberated, 17 for April 1945, and 19 for May 1945, when Germany surrendered to the Allied Forces. [ABSTRACT FROM AUTHOR]; Copyright of Mens en Maatschappij is the property of Amsterdam University Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)


This paper investigates the corporate governance voluntary and non-voluntary disclosure practices of the listed companies from four European emerging countries, namely Estonia, Poland, Hungary and Romania. The study also identifies how compliant are the companies from these countries with their national corporate governance recommendations, including the compulsory corporate governance information, but also how willing they are to disclose voluntary corporate governance information. Finally, the paper aims to analyse the factors that influence companies from these countries to disclose certain types of information, trying to discover whether the companies' corporate governance systems are mostly influenced by their national business or legal environment or if there are more powerful internal factors which influence the enforcement of certain corporate governance practices.


At this century, growth of cooler machine very go forward, Along with growth of technology and information, this time met many cooler machine / refrigerator which is used in materials process specially in course of and humidifikation of dehumidifikation. On the basis of the require to the existence of a research to analyse influence of variation speed of secretory air of FCU and heater burden variation of to air characteristic distrisbusi in cold storage and also the nature of wet air termal exist in cold storage. In this case research done conducted with test-drive use cooler machine installation air cooled chiller special design that is by adding heater element in cold storage with heater energy variation of and variation of speed of air go out from FCU. Of equipments of this test is expected by the happening of degradation of dampness of air, and how its distribution [at] system and also know the nature of wet air termal exist in cold storage. Result of which is obtained from this examination that is at a speed of air go out from FCU 0.45 with heater burden 60 watt on course I got by dampness of relative ( RH ) equal to 90.4 %, dry ball temperature ( Tbk ) equal to 23.56 ° C, and dew point temperature ( Td ) equal to 21,228 ° C.


Abstract The time and height variations of temperature, wind speed, and moisture content observed at the Cedar Hill tower during the dissipation of a low-level jet on the morning of 14 May 1962 are presented and discussed. Three distinct stages of significant variations occur before sunrise at the upper levels of the tower. The three stages art: 1) a period of an abrupt and simultaneous warming and drying; 2) a period of steady temperature, mixing ratio, and wind speed; and 3) a period of pronounced decreases in temperature and wind speed and a marked increase in mixing ratio that occur progressively later with increasing height. It is proposed that these variations are produced by horizontal and vertical advection and by turbulent mixing.


Postpartum hemorrhage is a major cause of maternal mortality. The World Health Organization (WHO) estimated 800 women die each day from complications of pregnancy and childbirth. Approximately 99% of all maternal mortality occur in developing countries. Based on the Indonesian Demographic and Health Survey (IDHS) in 2012, Maternal Mortality Rate (MMR) in Indonesia reached 359 per 100.000 live births. This study aimed to find out the relationship between the incidence of postpartum haemorrhage with maternity mother characteristics which include parity, maternal age, distance of pregnancy, and anemia in Harapan Kita Maternity Hospital during the period of 2013-2017. Methods: This was an analytic study with cross sectional design. Population were all the mothers who gave birth in Harapan Kita Maternity Hospital during the period of 2013-2017. Of the total population, 43 cases were selected as sample using the total sampling method. Data obtained using secondary data with complete medical records as a criteria for inclusion, bivariate analyzis were peformed using chi square. Results: The results of this study indicate, most postpartum hemorrhage is caused by uterine atony (46.51%). For the characteristics that influence consists of ages between 20-35 years (55.90%), pregnancy ≥ 2 years (86.05%), parity 2-3 (53.50%) and those with Hb level ≥ 11 g/dl% (76.74%). The results of the statistical test chi square shows a mother's gestational age between 20-35 years and parity had a close relationship with the incidence of postpartum haemorrhage due to the rest of the placenta with p value = 0.032 (p <0.05) for the age and p value = 0.030 (p < 0.05) to parity. Conclusion: The conclusion obtained that there is a relationship between maternal characteristics based on age and parity with postpartum haemorrhage, and there is no relationship between maternal characteristics based on the distance of the pregnancy and Hb levels (anemia) with postpartum haemorrhage in Harapan Kita Maternity Hospital during the period of 2013-2017.
Keywords : Maternity mother, Mother Characteristics, Postpartum hemorrhage


A simple austenitic steel beam specimen with a single autogenous weld bead laid along its top edge is an ideal training problem for novice weld modellers. This geometry may be analysed using either 3D or 2D FE models and employing either block-dumped or moving heat source techniques, with a variety of material constitutive models. This paper describes a residual stress simulation round robin performed on the validation benchmark problem of this type recently added to the R6 defect assessment procedure. A variety of solution strategies of increasing complexity are applied to the problem and the results compared with accuracy targets specified in the validation benchmark. It is found that the greatest solution accuracy is obtained using a 3D moving heat source, and mixed isotropic-kinematic material hardening behaviour.Copyright © 2013 by ASME


Too hungry to eat, too hungry not to eat Pancreatic beta cells, the source of insulin in response to food, employ an unusual mechanism to adapt to nutrient depletion. Goginashvili et al. found that starvation of beta cells induced selective degradation of newly formed insulin granules through their fusion with lysosomes, the cell's garbage disposal units (see the Perspective by Rutter). The nutrient sensor mTOR is recruited to these lysosomes, leading to its local activation and the suppression of autophagy—a process by which cells "eat" their own constituents. Protein kinase D, a major regulator of insulin granule biogenesis, controls this granule degradation in response to nutrient availability. Thus, unlike most other cells, autophagy is not the strategy of choice in beta cells to adapt to starvation. Science, this issue p. 878; see also p. 826 Newly formed insulin granules are degraded by lysosomes to prevent insulin release upon fasting. [Also see Perspective by Rutter] Pancreatic β cells lower insulin release in response to nutrient depletion. The question of whether starved β cells induce macroautophagy, a predominant mechanism maintaining energy homeostasis, remains poorly explored. We found that, in contrast to many mammalian cells, macroautophagy in pancreatic β cells was suppressed upon starvation. Instead, starved β cells induced lysosomal degradation of nascent secretory insulin granules, which was controlled by protein kinase D (PKD), a key player in secretory granule biogenesis. Starvation-induced nascent granule degradation triggered lysosomal recruitment and activation of mechanistic target of rapamycin that suppressed macroautophagy. Switching from macroautophagy to insulin granule degradation was important to keep insulin secretion low upon fasting. Thus, β cells use a PKD-dependent mechanism to adapt to nutrient availability and couple autophagy flux to secretory function.


The objectives of this work were to evaluate the hygienic and sanitary conditions of a light diet of a hospital in the city of Belem, state of Para (Brazil), using microbiological analysis of its compounds (fecal coliforms, Staphylococcus aureus and Salmonella) and of utensils, equipment's and employees' hands (fecal coliforms, Staphylococcus aureus), and to provide an inspection technical report of the hospital Food and Nutrition Unit, according to Annex II of the 1428th Regulation (11/26/1993) of the Ministry of Health to verify the implementation of the Good Manufacturing Practices. None of the samples presented Salmonella or Staphylococcus aureus; however, the compounds, utensils and equipments presented 100% of fecal coliforms contamination, as well as two workers' hands. The main points identified for the technical report were: Identity and Quality Standard, Environmental Conditions, Building Maintenance and Sanitary-Conditions, Equipments and utensils, Human Resources, adapted Technology, Quality Control, Quality Assurance, Storage, Disinfection and disinfestation. It was concluded that the evaluated Food and Nutrition Unit presented very bad hygienic and sanitary conditions.


The simple, yet powerful concept of an ldquoerristorrdquo and its ldquoerristancerdquo has recently been introduced for ad hoc networks and applied to scenarios such as retransmission (time diversity), path diversity, or a combination thereof. We extend this formalism to the case of spatial diversity, realized by employing multiple antennas at each node. Based on this framework, one can efficiently analyze and design Rayleigh-faded MIMO ad hoc networks that employ selection combining. The mathematically tractable definition of the erristor term greatly simplifies the study of a multiple-antenna network and helps solve problems based on end-to-end reliability or resource allocation easily, which we illustrate in an example. Moreover, this technique demonstrates the superiority in performance of MIMO over single-antenna routing schemes, particularly at high SNR.


We propose a novel planning technique for satisfying tasks specified in temporal logic in partially revealed environments. We define high-level actions derived from the environment and the given task itself, and estimate how each action contributes to progress towards completing the task. As the map is revealed, we estimate the cost and probability of success of each action from images and an encoding of that action using a trained neural network. These estimates guide search for the minimum-expected-cost plan within our model. Our learned model is structured to generalize across environments and task specifications without requiring retraining. We demonstrate an improvement in total cost in both simulated and real-world experiments compared to a heuristic-driven baseline.


INTRODUCTION
Following the adoption of the new international diagnosis classification from the Diagnostic and Statistical Manual (DSM-5), autism spectrum disorder (ASD) has been established as a dimensional category that includes other disorders that were previously considered as separate entities. Previous research has shown that some people with this disorder exhibit different communicative and linguistic profiles. Therefore, contradictory results could be found among people who receive the same diagnosis.

AIM
To distinguish structural language aspects (expression and comprehension), interactive aspects (pragmatics), and social adaptation between children with an ASD-level 1 of support and children with typical development.

SUBJECTS AND METHODS
Seventeen children with Asperger syndrome (according to the DSM-IV-TR), and 20 children with typical development between 7 and 12 years old. We have equated diagnosis of Asperger syndrome with ASD-level 1 of support. We have evaluated intelligence quotient, communication, and social adaptation with direct and indirect standardized parental scales.

RESULTS
We have found significant differences in comprehension (p = 0.025), interaction (p = 0.001), and social adaptation (p = 0.001) between the two groups.

CONCLUSIONS
Subjects with ASD-level 1 of support demonstrate an average intelligence quotient, and good expressive structure (syntax and semantic level), which may be different from other children who receive the same diagnosis, due to the wide heterogeneity of the disorder. Nevertheless, our subjects have problems related to comprehension of grammar structure, pragmatics, and social adaptation. These difficulties could be related to emotional and social problems.


Considering high-availability of the storage system has become a highly desirable property for network attached storage systems, we develop a special software application supporting the dual-computer fault-tolerant scheme. In this paper, we describe the design and implementation of a dual-computer fault-tolerant system. It includes two fundamental techniques: data mirroring and failover. The data mirroring technique is based on logging and tracking scheme. The failover is realized by heartbeat detection and automatically take over functions. According as availability definition, the theoretical analysis for the dual-computer system has been presented. The finds show that the integration of data mirroring and failover techniques can provide higher availability for the network based storage systems. Network managers can turn to this dual-computer scheme as the solution to resolve the increased demand on the file system availability at file server level.


Conflict of jurisdiction between the Civil and Syari'ah court is not a new issue in a dual legal system such as in Malaysia. Intense debatescalates when deciding on custodial rights after divorce in an interfaith marriage. The unilateral conversion to Islam by one party in a non-Muslim marriage has an impact on the status of the marriage and it is a legally recognised ground for divorce. Asignificant development is when the custody of a child is an issuesince both parties are no longer subject to the same set of laws andcourts for the purpose of adjudication. The current practice suggeststhat the converted parent is given preference in custodial rights bythe Syari'ah court, which is consistent with the view of the Shafi'ischool of law. The approach has caused dissatisfaction particularlyamong non-Muslim spouses who question whether the decision hasserved the best interest of the child especially in cases where thechild is very young. This paper seeks to examine the extent of thejurisdictional conflict in interfaith custody disputes in Malaysia andthe principle applied in the determination of each case. The researchmethod employed in this study is mainly a textual analysis of relevantmaterials and resolved cases relating to interfaith custody disputes.The study also adopts qualitative analysis in examining the strengthand weaknesses of the existing law in resolving the conflicts. Judicial interpretation and the judgments of the court are also analysed inidentifying relevant principles adopted by both Civil and Syari'ahcourts. The study concludes that of paramount importance is the bestinterest of the child which must be the guiding principle in decidingcustodial rights in interfaith custody disputes, besides other disputeresolution mechanisms.


Repaglinide is type 2 short acting anti-diabetic drug which is primarily metabolized by CYP2C8 and CYP3A4 and is also a substrate of influx transporter OATP1B1. HIV drugs are potent inhibitors of CYP3A4 and OATP transporters. Several drug-drug interactions (DDIs) were noticed when protease inhibitors (PIs) coadministered with drugs metabolized by CYP3A4. The PIs are also potent mechanism based inhibitors, out which ritonavir is most potent. In the current study we evaluated in vitro (mouse and human liver microsomes) and in vivo DDIs of repaglinide with anti-HIV drugs. Out of the following tested drugs (Amprenavir, Indinavir, Nelfinavir, Ritonavir, Saquinavir, Delavirdine, Maraviroc, Efavirenz, Nevirapine and Ketoconazole) Amprenavir (APV), Ritonavir (RTV) and Ketoconazole (KTZ) showed inhibition of OH-repaglinide formation in human and mouse liver microsomes. The positive reversible inhibitions were further tested for irreversible inhibitions where we didn't observe any irreversible inhibitions. In vitro inhibitions were further evaluated in the in vivo pharmacokinetics (mouse) where repaglinide pharmacokinetics was altered by RTV and KTZ. The DDIs in both studies were very strong; the dose of repaglinide is reduced to 20 fold. In conclusion, there could be possible DDIs when RTV dosed with repaglinide; we have also demonstrated that mouse could be useful preclinical tool when used in conjunction with in vitro screening models for DDIs.


Aims: In the era of targeted therapeutics, histological typing of hepatobiliary carcinomas has major clinical implications. Little is known about the reproducibility of the pathological diagnosis of primary liver carcinomas. Therefore, this study aimed to evaluate the worldwide variation in the pathological expert diagnoses of primary liver carcinomas with fibrous stroma in patients who did not have cirrhosis. Methods: A single set of slides was selected from 25 tumours, and this set was reviewed independently by 12 pathologists who have worldwide expertise in liver tumours. Reproducibility of the diagnoses was evaluated by Light's κ, and diagnoses were clustered by multidimensional scaling. Immunohistochemistry was performed after histological review. Results: The interobserver reproducibility for diagnosis of hepatocellular carcinoma subtypes and cholangiocarcinomas was poor (κ 0.23–0.52), even when the experts considered that the diagnosis required no additional stains or clinical information. Interestingly, multidimensional scaling revealed three main clusters of tumours: hepatocellular carcinoma with no other specifications (n = 13), fibrolamellar hepatocellular carcinoma (n = 3) and cholangiocarcinoma (n = 9). Using immunohistochemistry, these histological clusters correlated with expression of anti-hepatocyte and anti-cytokeratin 19 (p<0.001). Conclusions: The results demonstrate the poor reproducibility among experts of the pathological diagnosis of primary liver carcinomas with fibrous stroma in patients who did not have cirrhosis, and highlight that the systematic use of immunohistochemistry may improve the diagnostic accuracy.


With the increase in the use of the internet for educational purposes, the problem is no longer how to find and access information on-line, but how to select the most appropriate sources of information. What strategies do students adopt in order to allocate time adaptively to the information they need to learn? How and when do they make decision judgements, and how can this enable educators to facilitate student learning? If we understand how students search and retrieve information from texts, then we can design our texts to facilitate this process and ultimately enhance learning through minimising the time it takes for students to search for information within a text, and maximise the time they have for learning that information. This paper will present a new and innovative model of adaptive allocation of time across on-line texts, based on the principles of satisficing and skimming. It will discuss how knowledge about students' information search and retrieval processes can aid educational text designers in designing texts that will enhance student learning.


The link between humans and computers, called human-computer interaction (HCI) techniques, has the potential to improve quality of life, where analysis of the information collected from humans through computers allows personal patient requirements to be achieved. Among them, a computer vision system for helping elderly patients currently attracts a large amount of research interest to avail of personal requirements. This paper proposes a real-time computer vision system to recognize hand gestures for elderly patients who are disabled or unable to translate their orders or feelings into words. The proposed system uses a Microsoft Kinect v2 Sensor, installed in front of the elderly patient, to recognize hand signs that correspond to a specific request and sends their meanings to the care provider or family member through a microcontroller and global system for mobile communications (GSM). The experimental results illustrated the effectiveness of the proposed system, which showed promising results with several hand signs, whilst being reliable, safe, comfortable, and cost-effective.


The physical properties of laboratory-prepared anhydrous ionic liquid microemulsion, including quasi-ternary phase diagram, conductivity, surface tension, and simulating graph of a microscopic particle system were investigated to maintain the optimum ratio of CTAB (Hexadecyl trimethyl ammonium Bromide) and n-butyl alcohol at 1/24 to 1/12. The microemulsion region can reach a maximum of 75% at lower temperatures. We constructed a combined pretreatment of quadrol and anhydrous ionic liquid microemulsion on masson pine powder and analyzed its properties by Fourier-transform infrared, thermogravimetric analysis-derivative thermogravimetry, XRD (X-ray diffraction), and scanning electron microscope. Results showed that hemicellulose and a noncrystalline region in cellulose were disrupted effectively after pretreatment. Relative crystallinity increased from 35.8 to 49.8. A few crystalline structures of cellulose I were recrystallized and then transformed to cellulose II as indicated by IR, XRD, and DTG results. Thermostability decreased, and the region with a main thermal weight loss at 375°C shifted to the region with a lower temperature at 310°C. The yield of glucose can reach to 78.2%, which is 2.2 times than that of untreated powder; the combined pretreatment is an effective method to promote the development of bio-energy. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014, 131, 39794.


OBJECTIVE
To explore a new method in order to extract DNA from bones and teeth automatically.

METHODS
Samples of 33 bones and 15 teeth were acquired by freeze-mill method and manual method, respectively. DNA materials were extracted and quantified from the triturated samples by AutoMate Express forensic DNA extraction system.

RESULTS
DNA extraction from bones and teeth were completed in 3 hours using the AutoMate Express forensic DNA extraction system. There was no statistical difference between the two methods in the DNA concentration of bones. Both bones and teeth got the good STR typing by freeze-mill method, and the DNA concentration of teeth was higher than those by manual method.

CONCLUSION
AutoMate Express forensic DNA extraction system is a new method to extract DNA from bones and teeth, which can be applied in forensic practice.


The Dachang tin-polymetallic ore field, Guangxi, People9s Republic of China, is one of the largest in the world and contains the Changpo, Bali, and Longtaoshan tin-base metal deposits, the Dalfulou black shale-hosted cassiterite-sulfide deposit, and the Lamo Cu-Pb-Zn proximal skarn deposit. These are hosted by Devonian carbonate-rich sediments metamorphosed to hornblende hornfels facies near the underlying Yanshanian Longxianggei granite (91 Ma). Plutonic intrusion and relevant mineralization are controlled by the north-northwest-trending Longxianggei and Changpo anticlines. The conduit for distal skarn solutions was a reverse fault (F1). Tin mineralization at Changpo is genetically related to the S-type Longxianggei granite with proximal skarns precipitated near its contact and distal ores 300 to 500 m vertically away from the contact.Hydrothermal alteration is grossly zoned outward from the granite contact as follows: (a) proximal ore skarn zone (garnet and pyroxene), (b) tourmaline-silicified zone, (c) sericite (+ or - cassiterite) zone, and (d) carbonate(-sulfosalt) vein zone. Zones b to d do not occur above the Lamo deposit whereas zone a is missing directly below the large Changpo deposit but occurs lateral to it. Nearest to the granite outcrop, the Lamo Cu-Pb-Zn proximal skarn is developed with a temporal sequence of stages: (A) garnet-vesuvianite-wollastonite + or - diopside, (B) Ca amphibole-epidote-fiuorite-quartz, (C) biotite-sericite-sulfides, and (D) sulfides-carbonate-chlorite. Distal skarns have the following temporally and spatially distributed stages: (1) tourmaline-quartz-cassiterite, (2) arsenopyrite-cassiterite (+ or - other sulfides), and (3) sulfosalts-carbonate (most distal).There is a zonal pattern of both temperatures and ore fluid compositions deduced from fluid inclusions as follows: proximal skarn zone: 450 degrees to 600 degrees C, CO 2 /CH 4 35 wt percent NaCl equiv; tourmaline-silica zone: 350 degrees to 450 degrees C, CO 2 /CH 4 = 0.10 to 10.00, salinity = 12 to 30 wt percent NaCl equiv; sericite zone: 250 degrees to 350 degrees C, CO 2 /CH 4 >10, salinity 2 dominated, no CH 4 , salinity = 6 to 8 wt percent NaCl equiv.Daughter crystals include antarcticite (CaCl 2 . 6H 2 O), halite, sylvite, carbonate, MgCl 2 . 6H 2 O), and fluorite. Thermodynamic calculations based on fluid inclusion composition and measured temperature show that f (sub O 2 ) values of the ore-forming stages were very low, well below the FMQ buffer and increased from early to later stages. Tin precipitation was affected by a low oxygen fugacity of ore fluids partly resulting from the occurrence of black shale, and a decrease in temperature.


Current interest in high-sensitivity receivers for frequency modulation is centered around two implementations of the device: phase-lock and frequency-feedback. Enloe and later Cahn presented linearized frequency-feedback receiver design theory based on a twin threshold concept. This paper presents the derivation of a quasi-linear model for the frequency-feedback receiver for the situation of Gaussian signals and noise. A statistical optimization is then performed giving the loop transfer function and threshold performance for a maximum sensitivity receiver. The design theory is based on a single threshold concept deviating from previous twin threshold approach. It is shown that in an optimum design the modulation error is less than 1 rad. This allows the use of a narrow-band IF filter and obviates the need to consider threshold characteristics of the discriminator within the loop. A significant result of this analysis is that although the quasi-linear receiver models differ in detail, threshold for a maximum sensitivity FM feedback and for a phase-lock receiver is identical. It was found that in FM feedback, as previously determined by Develet for the phase-lock receiver, threshold occurs at 10 log10(e)= 4.34 db above the ultimate limit determined by information theory arguments. This 4.34-db degradation is independent of modulation index. It is anticipated that the results in this paper will free the design engineer from concern about which device is theoretically better and allow his choice to be influenced solely by hardware considerations.


The design of bit-interleaved turbo-coded modulation (BITCM) in OFDM-based wireless LAN systems is studied. It is observed that for the frame size commonly used in wireless LAN applications, a larger constraint length in turbo codes does not necessarily introduce significant improvement in the BITCM performance in the signal-to-noise ratio range of interest, and it even leads to performance degradation in some cases. An explanation is provided from the viewpoint of weight distribution of turbo codes. Extensive performance evaluation indicates that BITCM with a constraint length of four has a good tradeoff between the performance and complexity for the OFDM-based wireless LAN system.


Indonesia with a Muslim population reaching 87.17% is very strategic for the development of halal industry. But the halal industry in Indonesia has not grown optimally. One reason is the lack of Islamic financial literacy, whereas literacy greatly influences the financial decisions taken. The government organization, BPJPH, which handles certification and provides Islamic financial literacy, has not yet operated. Therefore we need an innovative solution that is a smart system about Education and Investment for halal industry. The research methodology used is descriptive qualitative. Through quantitative research with one sample t test using descriptive analysis and each 1 research variable. This system is a concept of innovation in the field technology that can be a bridge for government organizations namely BPJPH to provide Islamic financial literacy. Not just giving literacy, but also offering alternative solutions for submission of sharia-compliant capital loans. This system brings together important elements in the halal industry cycle, namely halal industry players, Islamic banking, investors and the government as regulators through an application. Increased Sharia financial literacy and the potential of Return of Investment in halal industries can be realized. This is evidenced by an increase of 80% to the understanding of the halal industry from before, and the potential increase in capital and profits that reached a Return of Investment of 14.3% in the calculation of research samples in the province of East Java. This shows the benefits and success of the application of smart education and investment systems for the halal industry in Indonesia.
Keywords: Islamic financial literacy, Islamic finance, technology


Robot navigation based on determining the relative position of visible landmarks and then using this information to estimate the robot's location is considered. Accuracy is difficult to obtain, because measurements are approximate and combining them can lead to large errors in localization. However, a careful choice of landmarks can decrease errors before they occur. The problem of determining viewpoint position, given relative visual angles between landmarks, is addressed. It is shown that for any given error in angle measurement the error in localization can vary significantly, depending on the configuration of landmarks used. The authors demonstrate how an algorithm which makes a wise choice of landmark configurations can decrease error. The algorithm's performance is compared to that of using landmarks chosen indiscriminately.<<ETX>>


Unit testing is a technique of testing a single unit of a program in isolation. The testability of the unit under test can be reduced when the unit interacts with its environment. The construction of high-covering unit tests and their execution require appropriate interactions with the environment such as a file system or database. To help set up the required environment, developers can use mock objects to simulate the behavior of the environment. In this paper, we present an empirical study to analyze the use of mock objects to test file-system-dependent software. We use a mock object of the FileSystem API provided with the Pex automatic testing tool in our study. We share our insights gained on the benefits of using mock objects in unit testing and discuss the faced challenges.


Phytoplankton is an important indicator of water quality assessment. To understand phytoplankton dynamics, many fixed buoys and ferry boxes were implemented, resulting in the generation of substantial data signals. Collected data are used as inputs of an effective monitoring system. The system, based on unsupervised hidden Markov model (HMM), is designed not only to detect phytoplancton blooms but also to understand their dynamics. HMM parameters are usually estimated by an iterative expectation-maximization (EM) approach. We propose to estimate HMM parameters by using spectral clustering algorithm. The monitoring system is assessed based on database signals from MAREL-Carnot station, Boulogne-sur-Mer, France. Experimental results show that the proposed system is efficient to detect environmental states such as phytoplankton productive and nonproductive periods without a priori knowledge. Furthermore, discovered states are consistent with biological interpretation.


A 10-year-old boy was referred to the BMT department for treatment of MDS (refractory anemia with excess 20% myeloblasts). The conditioning for BMT included total lymphoid irradiation (600 rad), VP16 (1,275 mg), cyclophosphamide ( 1,260 mg), melphalan (5 I mg) and total body irradiation (1,200 rad). On the day of transplant (day 0) the patient received BM (8.4 X lo* cells/kg body weight), T-cell depleted with monoclonal antibody (rat anti-human IgG antiCDw52) from his HLA matched sister. The course of BMT was completed by graft rejection on post-BMT day 5.5. A second BMT was performed with cells from the sister, but without T-cell depletion. Prior conditioning consisted of anti-thymocytic globulin for 3 days and one dose of cyclophosphamide (60 mg/kg body weight). Granulocyte macrophage colony stimulating factor (GMCSF) and Interleukin-3 (lL3) were given post-BMT to enhance engraftment. On day 2 after the second BMT, (57 days post first BMT) while receiving broad spectrum antibiotics (imipenem, vancomycin, amikacin) and amphotericin B (0.5 mg/kg; asphophlactic dose) the patient developed fever, neutropenia, cough, inspiratory wheezing and his abdomen was distended. A day later he was in acute respiratory distress with consolidation in the right upper lobe as determined by chest radiography. Flexible fiberoptic endoscopy detected an obstruction by white material in the opening of the left main bronchus (LMB). Histopathological examination of the material, obtained by suction through the bronchoscope, revealed typical aspergillosis hyphae. No bronchial or transbronchial biopsies were carried out. A second rigid bronchoscopy was performed


This study investigated the morphology of the recurrent facial taste neurons and their organization in the recurrent ganglion of the sea catfish Plotosus japonicus. The recurrent ganglion is independent of the anterior ganglion, which consists of trigeminal, facial and anterior lateral line neurons that send peripheral fibres to the head region. The recurrent taste neurons are round or oval and bipolar, with thick peripheral and thin central fibres, and completely wrapped by membranous layers of satellite cells. Two peripheral nerve branches coursing to the trunk or pectoral fin originate from the recurrent ganglion. The results presented here show that the trunk and pectoral-fin neurons are independently distributed to form various sizes of groups, and the groups are intermingled throughout the ganglion. No distinct topographical relationship of the two nerve branches occurs in the ganglion. Centrally, the trunk and pectoral-fin branches project somatotopically in the anterolateral and intermediate medial regions of the trunk tail lobule of the facial lobe, respectively.


In brief: Magnetic resonance imaging (MRI). has become a standard diagnostic technique in many medical facilities for evaluating the menisci of the knee. MRI provides superior soft-tissue contrast with high resolution and takes little time (typically less than 30 minutes). It does not require intra-articular contrast media and is not limited to surface abnormalities, as are arthrography and arthroscopy. Unlike MRI, both arthrography and arthroscopy cause disturbances to the external capsule of the knee, with associated patient discomfort and limited physical activity for some time following the procedure. The author discusses the advantages of MRI and presents a case report in which it was used to make the diagnosis and determine the appropriate treatment modality.


An ultralow dark-signal and high-sensitivity pixel has been developed for an embedded active-pixel CMOS image sensor by using a standard 0.35-/spl mu/m CMOS logic process. To achieve in-pixel dark-current cancellation, we developed a combined photogate/photodiode photon-sensing device with a novel operation scheme. The experimental results demonstrate that the severe dark signal degradation of a CMOS active pixel sensor is reduced more than an order of magnitude. Through varying the bias conditions on the photogate, dynamic sensitivity can be obtained to increase maximum allowable illumination level. Combining the above two operation schemes, the dynamic range of this new cell can be extended by more than 20/spl times/.


We ask what type of mixed quantum states can arise when a number of separated parties start by sharing a pure quantum state and then this pure state becomes contaminated by noise. We show that not all mixed states arise in this way. This is even the case if the separated parties actively try to degrade their initial pure state by arbitrary local actions and classical communication.


Plants respond to various environmental factors. Bioelectric potential is used to examine such responses. The bioelectric potential of pothos pots in response to light intensity, atmospheric temperature and air volume have been examined. From our results, it is clear that the potential changes with environmental factors. In this study, two pothos pots were set up in a living space, and the bioelectric potentials of the pots were examined to investigate whether there are any marked individual differences between the two. If there is a noticeable difference, the effective application of the bioelectric potential becomes relatively limited. We found a correlation coefficient of 0.7 between the potentials of the two plants under darkness and the operation of an air conditioner. A proposed summarized value was adopted to analyze the bioelectric potential. Individual differences were identified to some degree, but the characteristics closely resembled each other. The coefficient between the summarized potentials exceeded 0.85 as time progressed. It is considered that plants can function as sensors of environmental factors.


Morphological changes of γ ́ precipitates in nickel based single crystal superalloy CMSX4 were studied during long-term ageing at four temperatures of 900, 925, 950 and 1000°C and various ageing times up to 4000 h. The precipitates were extracted from the γ (Ni based solid solution) matrix into thin carbon extraction replicas and then studied by scanning electron microscopy (SEM) and transmission electron microscopy (TEM). Using quantitative metallography, emphasis was set on real three-dimensional shape of such extracted γ ́ precipitates. It was found out that long-term ageing leads to a change of some cuboidal shaped precipitates to precipitates with so called spontaneous rafted morphology. At a temperature of 950 °C, spontaneous rafted precipitates were found after 3000 h of isothermal ageing. The temperature of 1000 °C was used to accelerate this type of degradation process and to increase occurrence of spontaneously rafted precipitates in the microstructure for their better observation and analysis. Eventual physical based aspects of spontaneously rafted γ ́ precipitates occurrence are discussed in this paper.


The presence of volatile organic compounds (VOC), produced and released from both anthropogenic and natural sources, can accelerate the degradation of air quality in the surrounding area. In this study, we investigated the emission concentrations of VOC based on a total of 115 sample analysis made from 47 companies (representing 17 types of industry) at the Ban Wall industrial complex (Jun. 2004 to Jan. 2005). Through a statistical analysis of these measurement data, we inspected the emission characteristics of VOC in relation with industrial type and processing unit. When these data were compared each other, toluene was found to record the highest value of 423 ppb followed by ethylbenzene (68.3 ppb), m, p-xylene (43.6 ppb), o-xylene (27.2 ppb), styrene (23.9 ppb), and benzene (16.4 ppb). In addition, by converting these VOC concentration data into malodor intensity, we attempted to account for their distribution patterns in terms of relative contribution to the malodor formation. The results of odor intensity conversion generally indicated that the odor intensities of individual VOC do not exceed the degree of 1. When our VOC results were compared against other odorous compounds measured concurrently, the results were highly contrasting each other. Despite relative insignificance as odorous compounds, these VOCs are generally found ubiquitously and in abundant quantities in this strong source area.


This study used a suitable solvent such as deionized water and aqueous acetic acid to dissolve completely polymer blends such as gelatin: chitosan: pullulan (G: CS: PUL) with mixing ratios of 80:10:10, 60:20:20, 40:30:30, 20:40:40 respectively. The properties of natural polymer mixtures, viscosity, surface tension, and electrical conductivity were examined, and the fiber diameter and nanofiber diameters distribution were measured. Increasing the gelatin content from 20% to 80% in the G: CS: PUL increases the properties of biopolymer solutions, such as viscosity, surface tension, and electrical conductivity 157%, 14%, and 37%, respectively. In addition, increasing the gelatin content reduces the contact angle by 55%. In other words, the average diameter of the nanofibers increased from 91.177 ± 27.162 to 212.46 ± 67.91 nm with the increase of the gelatin content by 40 % - 100% in the blends and obtaining uniform fibers without beads, which enhanced the ability of nanofibers for releasing into the aqueous media and enhancing their use in packaging food such as (80:10:10 and 60:20:20). Moreover the blend ratio 60:30:30 (G:CS: PUL) had better resistance to bacterial growth, the inhibition zone diameters were 26 and 23 mm for E. coli and S. aureus and had better average crystalline size and crystallinity.


Unstructured grid solvers have well-known issues predicting surface heat fluxes when strong shocks are present. Various efforts have been made to address the underlying numerical issues that cause the erroneous predictions. The present work addresses some of the shortcomings of unstructured grid solvers, not by addressing the numerics, but by applying structured grid best practices to unstructured grids. A methodology for robust shock detection and shock fitting is outlined and applied to production relevant cases. Results achieved by using the Loci-CHEM Computational Fluid Dynamics solver are provided.


PATIENTS AND METHODS
In this present retrospective study we examined 62 long-term ventilated patients, whose weaning from respirator failed, for endoscopic airway complications and the frequency of consecutive surgery required. Furthermore noninvasive volume-controlled intermittent ventilation was evaluated as an alternative method to tracheostomy for maintaining mechanical ventilation and weaning of patients with chest wall disorders, neuromuscular and chronic obstructive lung disease.

RESULTS
25 patients with endotracheal tube and 37 with tracheostomy who had been long-term ventilated in different intensive care units for 18 +/- 12 respectively 57 +/- 27 days (19 +/- 12 days via endotracheal tube) could be weaned successfully consequently using a volume-controlled intermittent ventilation via an individually adapted face mask. We found 2 patients of the group with endotracheal intubation (median age 59 +/- 15 years, 11 female, 14 male, median duration of mechanical ventilation via tube 18 +/- 12 days) to have visible injuries of the respiratory tract without consecutive surgery being necessary. All of them were successfully weaned from respirator via noninvasive ventilation (in 2 of them completely spontaneous breathing was re-established, 23 patients needed intermittent ventilation at home). Of the 37 patients with tracheostomy (median age 59 +/- 15 years, 15 female, 22 male, median duration of mechanical ventilation 57 +/- 27 days, tracheostomy on day 19 +/- 12) 19 cases (51%) showed endoscopically visible injuries of the respiratory tract of whom 7 cases (19%) were severe and made consecutive surgery necessary. 29 patients were discharged with noninvasive ventilation at home, 5 needed further invasive ventilation via tracheostomy and 3 patients breathed spontaneously without ventilatory support. The incidence of severe tracheal stenosis following long-term ventilation via tracheostomy was nearly 20% (1 tracheoesophageal fistula) and needed surgical treatment.

CONCLUSION
As even duration of ventilation via tracheal tube and mode of ventilation before transfer to our clinic was comparable in both groups noninvasive ventilation is an appropriate alternative to tracheostomy following endotracheal intubation for maintaining ventilatory support, especially for patients with chronic ventilatory insufficiency.


We propose a new mechanism for pulsar kicks, which is magnetohydrodynamically-induced kick. We carry out two-dimensional numerical simulations on the core-collapse of a massive star with differential rotation and initially large magnetic fields which have equatorially asymmetric dipole-like configuration. As a result of the computations, we get transient large kick velocities which are up to 500 km/s. However, these large velocities are soon damped since surrounding matter prevent proto-neutron-stars from moving away and finally no substantial kicks are produced. This may be a crucial problem for all pulsar kick computations.


We report a young patient who developed a stiff man syndrome (SMS) long after remission of Hodgkin lymphoma. This patient is remarkable because he has had several other potentially autoimmune or paraneoplastic neurological syndromes including limbic encephalitis and demyelinating polyneuropathy which also occurred years after remission from Hodgkin disease.


Close relationships are integral to the health and adaptation of our species. The evidence is incontestable, and it is the building block upon which future theory, research, and practice rests. This foreword notes the distinct domains and independent histories of relationship science and health psychology and calls for further thorough integration within the broader context of team science. The articles in this special issue focus on interpersonal mechanisms, cultural specificity, personality and emotion regulation, couples dynamics in chronic disease, and the increasingly complex biological mechanisms involved in linking relationships to health outcomes. They point to the importance of life stage, especially childhood and late adulthood, for understanding unique relationship and health issues. The challenge remains to translate existing and future knowledge into interventions to improve social relationships for the benefit of physical and mental health.


Fibrous dysplasia of the anterior cranial base involves the bony orbit and optic canal. Although fibrous dysplasia is benign, it may produce a mass effect along the course of the optic nerve, inducing visual disturbances. Optic canal decompression in patients without clinical signs of optic neuropathy is controversial. We describe five patients with extensive fibrous dysplasia of the anterior cranial base involving the orbit and optic canal. These patients underwent transcranial optic canal decompression before signs of severe visual loss during correction of dystopias and craniofacial deformity induced by fibrous dysplasia. Cranial orbital reconstruction was performed by means of split rib and cranial bone grafts. Postoperative follow-up did not reveal disturbances in visual function, extraocular motility, or evidence of cerebrospinal fluid fistulas. This suggests that early, radical resection of orbital fibrous dysplasia with optic canal decompression may be effective in preventing visual loss with minimal risk of other neurological sequelae. Subsequent orbital reconstruction involving split-thickness rib and cranial bone grafting yields satisfactory cosmetic results.


What Marx said of legal institutions applies in wide measure to literary forms. They cannot stand higher than the society which brought them forth. Indeed, since they deal with the deepest human laws, problems and contradictions of an epoch they should not stand higher-in the sense, say, of anticipating coming perspectives of development by romantic- Utopian projections of the future into the present. For the tendencies leading to the future are in fact more firmly and definitely contained in what really is than in the most beautiful Utopian dreams or projections (Lukcs 1983). Lukcs establishes here a strong foundation for the argument that novels are social formations that echo the dominant standards of a culture, at the same time that they seek to call attention to the paradoxes of those institutions. Cultures and countries that endure great tribulation seem destined to turn to literary realism as a default setting for narrative prose; the crucible that is the prison in such cultures provides a unique glimpse into the 'real' that Lukcs suggests. Many critics have recognized that the prison of Alex La Guma's The Stone Country stands in for South Africa during Apartheid.


The materials used to conduct kinetic study on the leaching of silver in the S2O32−-O2-Cu2+ system were mining residues (tailings) from the Dos Carlos site in the State of Hidalgo, Mexico, which have an estimated concentration of Ag = 71 g∙ton−1. The kinetic study presented in this paper assessed the effects of the following variables on Ag dissolution rate: particle diameter (d0), temperature (T), copper concentration [Cu2+], thiosulfate concentration [S2O32−], pH, [OH−], stirring rate (RPM), and partial pressure of oxygen (PO2). Temperature has a favorable effect on the leaching rate of Ag, obtaining an activation energy (Ea) = 43.5 kJ∙mol−1 in a range between 288 K (15 °C) and 328 K (55 °C), which indicates that the dissolution reaction is controlled by the chemical reaction. With a reaction order of n = 0.4, the addition of [Cu2+] had a catalytic effect on the leaching rate of silver, as opposed to not adding it. The dissolution rate is dependent on [S2O32−] in a range between 0.02 mol·L−1 and 0.06 mol·L−1. Under the studied conditions, variables d0, [OH−] and RPM did not have an effect on the overall rate of silver leaching.


Unbraced vinyl house frame that is economically installed is certainly easy to collapse under the influence of excess snow load. To make it more cheaply in putting up as well as more efficiently in withstanding the applied snow load, it is essential to insert additional bracing into the existing unbraced vinyl house frame. On the other hand, there are varieties of possible bracing shapes that can be formed. However, their efficiencies are different. Therefore, it is important to identify the most effective bracing shape. In this study, 2 different kinds of bracing shapes, horizontal and inclined bracing, are used to additionally install in the ordinary single frames in order to show the effect of the bracing resisting the applied snow load and compare the bending moment, axial force, combined stress and vertical displacement of the vinyl house frame.


In this work, we present an innovative approach for designing small-scale microcavity resonators. By introducing a gold cladding around the structure, we may significantly reduce the mode volume and simultaneously increase the cavity's quality Q-factor. By making use of the TE011 mode, as opposed to the more traditional HE111 mode, we may further reduce the mode volume while taking advantage of decreased loss into the metal layer due to the optimal polarization choice. We demonstrate a means to design and optimize the cavity geometry to obtain desired spectral characteristics through the use of particle swarm optimization, and we present a cavity operating at 1.5 mum with a Q value exceeding 300 000 and a modal volume of less than 0.9(lambda/n)3.


The cotton bollworm, Helicoverpa armigera (Hiibner) is an important pest in India damaging cotton crop and resulting in economic loss. Accurate and timely prediction of the pest, considering biotic and abiotic factors is essential to reduce the crop loss. In this paper, we present a neural-network classifier for predicting the pest incidence on cotton by considering the season, crop phenology, biotic factors (spiders and Chrysoperla zastrowi sillemi ) and abiotic factors such as maximum temperature, minimum temperature, rainfall and relative humidity. Single layer perceptron neural-network with back-propagation algorithm was utilized for the design of the presented intelligent system. Decision tree is presented from the proposed trained neural-network. The results showed that the supervised neural network system could classify or predict the pest incidence as either 'high' or 'low' based upon economic threshold level with high degree of accuracy. Extracting rules from the decision tree helps the user to understand the role of biotic and abiotic factors on H. armigera incidence.


Large proteomics data, including those generated by mass spectrometry, are being generated to characterize biological systems at the protein level. Computational methods and tools to identify and quantify peptides, proteins and post-translational modifications (PTMs) that are captured in modern mass spectrometers have matured over the years. On the other hand, tools for downstream analysis, interpretation and visualization of proteomics data sets, in particular those involving PTMs, require further improvement and integration to accelerate scientific discovery and maximize the impact of proteomics studies by connecting them better with biological knowledge across not only proteomics, but also other Omics domains. With the goal of addressing these challenges, the piNET server has been developed as a versatile web platform to facilitate mapping, annotation, analysis and visualization of peptide, PTM, and protein level quantitative data generated by either targeted, shotgun or other proteomics approaches. Building on our experience with large scale analysis of gene and protein expression profiles as part of the Library of Integrated Network Cellular Signatures (LINCS) project, piNET has been designed as a fast, versatile and easy to use web-based tool with three modules that provide mapping from peptides (with PTMs) to proteins, from PTM sites to modifying enzymes that target those sites, and finally from proteins (with PTMs) to pathways, and for further mechanistic insights to LINCS signatures of chemical and genetic perturbations. piNET is freely available at http://www.pinet-server.org.


Heavy metal such as lead has increase in the natural environment especially in the aqueous solution. Remediation method of adsorption offer a treatment for removing heavy metal in river. This experiment is to analyse and compare eggshell adsorbent of activated carbon in Panchor's river through its efficiency in removing heavy metal of Lead (II). Eggshell is designed as an activated carbon through physical and chemical activation in treating the water by undergoing adsorption process of few laboratory test. The efficiency of eggshell chemical activated carbon is high as the percentages removal of Pb is 48.21% compare to physical activated carbon with 32.14%. However, this study showed that both eggshell activated carbon is an effective adsorbent in removing Pb from aqueous solution of natural environment.


This investigation's purpose was to present and sustain a set of analysis categories applicable to a productive system, based on management approaches. To reach this objective, a bibliographic qualitative research was applied, looking for the representation of the categories identified over the management literature. Starting by the studies of Hanson and Voss (1995), there were identified thirteen categories, which analyses is necessary when considering a production system: production control, operational performance, new products development, technology and equipment, factory, environmental management, investment, organization and culture, production planning, production programming, quality, health and safety and time cycle. The results show that categories like quality, environmental management and health and safety were less studied by the traditional management approaches, however they were frequently analyzed by the emerging tendencies. The influence of the Classical Approach over the other categories theoretical foundation was also evident. Finally, it was verified that the thirteen proposed categories are representative to a production system analysis, based on management approaches.


Hantavirus pulmonary syndrome is a newly recognized rodent-borne zoonosis. We report a case of hantavirus pulmonary syndrome in an employee of a California utility company who was probably occupationally exposed to Sin Nombre virus. Environmental assessment and genetic comparison of the patient's hantavirus isolates to hantavirus isolates from rodents trapped at possible sites of exposure suggested that the patient contracted his infection at the work site. The study revealed a close correspondence between the patient's viral genotype and that from a rodent trapped at the work site. This report alerts the public health and medical community to the fact that employees of utility companies and similar industries may be an important risk group in areas where hantavirus is endemic and emphasizes the need to incorporate strategies for preventing exposure to hantavirus and other emerging infections into occupational safety protocols.


The pathogenesis of salivary gland neoplasms (SGN) has not been established. There is a real debate on clonality issues and all the definitive evidence is on the side of polyclonal tumor origin. Evidence that many tumor types may be polyclonal in origin has been published. Despite all this body of evidence, scientists have incorporated the clonal theory proposed by Knudson (1985) and only strengthen these results (and do not discuss contrary findings), because they think it is expected. There are few clonality studies on benign salivary neoplasms and almost no data on malignant neoplasms. The HUMARA assay was used in the present study to investigate the clonality of 27 samples of SGN (17 benign and ten malignant). Briefly, samples were digested with HhaI and HpaII methylation-sensitive enzymes and a PCR carried out. Eighteen out of 27 cases revealed monotypy, while three were non-informative and six showed heterotypy, indicating a true polyclonality. In summary, our results show evidence that a subset of SGN might be clonal in origin, while some samples are polyclonal. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 102nd Annual Meeting of the American Association for Cancer Research; 2011 Apr 2-6; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2011;71(8 Suppl):Abstract nr 2728. doi:10.1158/1538-7445.AM2011-2728


Nowadays, the high power GaN-based LED has attracted serious attention for the lighting application. One of key issues for high power GaN-base LED to achieve sufficient lighting efficiency over the traditional light sources, such as, white incandescent and halogen light bulb is the efficiency of heat dissipation. Typically, GaN epi-layer is grown on sapphire substrates. The poor thermal conductivity of sapphire substrate has been identified to be the main limitation for the application of high power GaN LED. To improve the heat dissipation and lighting efficiency, we report a thin GaN structure by using Au-Si wafer bonding and Laser lift-off (LLO) technique. The GaN wafer was first deposited with a Au bonding layer and bonded onto a good thermal conduction substrate, i.e., heavy-doped Si. Then, 248nm KrF excimer Laser was used to strip the original sapphire substrate. To assure a successful GaN epi-layer transferring, Raman spectrum on the transferred GaN layer was performed and the result shows no quality change in the transferred GaN layer. In this work, we also fabricated the vertical LED devices on the transferred GaN epi-layer. Therefore, L-I-V result was obtained which will be presented in this talk. Moreover, we will discuss the effects and advantages of Au-Si bonding on the efficiency of lighting.


ABSTRACT Background: In Indonesia, obesity prevalence remains high, and North Sulawesi was the highest number of obesity prevalence in 2019, with 30.2% of the 2.5 million population classified as overweight. Eating behavior and sedentary life style contribute the overweight incidents. This study aimed to determine the factors affecting obesity in preschool children in upper Airmadidi, North Sulawesi. Subjects and Method: A cross-sectional study was conducted in Airmadidi, North Sulawesi. A sample of 64 preschool children was selected for this study. The dependent variable was overweight. The independent variables were consumption of fried foods, diet intake, and sedentary lifestyle. The body mass index was measured by weight scale and microtoise. The data were analyzed by Pearson correlation. Results: As many as 17 preschool children were identified as overweight (Mean= 17.65; SD= 0.52) and 16 preschool children were obese (Mean= 19.05; SD= 0.94). There was a positive correlation of overweight in students with fried foods consumption (0.87), diet intake, (0.86), and sedentary life style (0.97). There was a positive correlation of obese in preschool children with fried foods consumption (0.84) and sedentary life style (0.81). Conclusion: Overweight and obese in preschool children are positively correlated with fried foods consumption, diet intake, and sedentary life style. Keywords: obese, overweight, preschool children, diet intake Correspondence: Jonan Stanley Nangoy. AIIAS. Km 45.5 Emilio Aguinaldo Hwy, Lalaan 1, 4118, Silang, Cavite, Philippines. Email: email@example.com. Mobile: +62811436079. DOI: https://doi.org/10.26911/the7thicph.03.75


Small silencing RNAs (sRNAs) are non-coding RNA regulators that negatively regulate gene expression by guiding mRNA degradation, translation repression or chromatin modification. Plant sRNAs play crucial roles in various developmental processes, hormone signaling, immune responses and adaptation to a variety of abiotic stresses. miR441 and miR446 were previously annotated as microRNAs (miRNAs) because their precursors can form typical stem-loop structures, but are not considered as real miRNAs because of inconsistency with some ancillary criteria of the recent guidelines for annotation of plant miRNAs. We tentatively rename them small interfering (si)R441 and siR446, respectively, in this study. It has recently been shown that the precursors of siR441 and siR446 might originate from the miniature inverted-repeat transposable element (MITE) Stowaway1. In this report, we show that, in contrast with Dicer-like (DCL)3- and RNA-dependent RNA polymerase (RDR)2-dependent MITE-derived ra-siRNAs, siR441 and siR446 are processed by OsDCL3a but independent of OsRDR2, indicating that siR441 and siR446 are generated from single-stranded stem-loop precursors. We also show that abscisic acid (ABA) and abiotic stresses downregulate the expression of siR441 and siR446 but, surprisingly, increase the accumulation of their precursors in rice plants, implying that processing of siRNA precursors is inhibited. We provide evidence to show that this defective processing is due to increased precursor accumulation per se, possibly by intermolecular self-pairing of the processing intermediate sequences, thus hindering their normal processing. Functional examinations indicate that siR441 and siR446 are positive regulators of rice ABA signaling and tolerance to abiotic stress, possibly by regulating MAIF1 expression.


An adaptive algorithm has been designed to treat interferometric self-mixing signals for weak and moderate laser feedback. With regard to the creation of an embedded displacement sensor, the reconstruction process is inspired from the interpolation feature found in digital-to-analog converters. By using an adaptive filter as the central process, the algorithm presents a high potential of parallelism to meet timing restrictions. A validation for different signal scenarios was carried out. The obtained precision and ease of maintainability enlightens its capabilities to be coupled with other signal processing methods to produce better system reliability.


Panawil (Leptosolena haenkei C. Presl) belongs to the family Zingiberaceae which is endemic to Northern Luzon, Philippines. It thrives in cluster in a very specific area of Benguet and Mountain Province. The phytonutrient analyses revealed that the indigenous vegetable panawil is a rich source of phytochemicals (terpenoids, tannins, flavonoids, total phenolics, and antioxidants); minerals (phosphorus, potassium, iron, and zinc); and vitamins A (β-carotene) and C (ascorbic acid). Phytonutrient analyses of the plant samples collected from different parts of Benguet and Mountain Province reveal that there is no significant difference, except that there is a high significant difference in vitamin C of panawil from both Benguet and Mountain Province.


Introduction. Gingival recession is an apical shift of the gingival margin with exposure of the root surface. This migration of the marginal tissue leads to esthetic concerns, dentin hypersensitivity, root caries, and cervical wear. It is, paradoxically, a common finding in patients with a high standard of oral hygiene, as well as in periodontally untreated populations with poor oral hygiene. Changing the topography of the marginal soft tissue in order to facilitate plaque control is a common indication for root coverage procedures and forms a major aspect of periodontal plastic surgeries. The regeneration of a new connective tissue attachment to denuded root surface is by allowing the selective coronal regrowth of periodontal ligament cells while excluding the gingival tissues from the root during wound healing by means of a barrier membrane. Case Presentation. This case reports a two-stage surgical technique for treatment of Miller's class III defect using free gingival autograft and type I absorbable collagen membrane (BioMend®, Zimmer Dental, USA)§. Conclusions. The 6-month follow-up of the case showed a significant increase in attached gingiva suggesting it as a predictable alternative in the treatment of Millers class III defects.


The methods of neutron diffraction and isotopic substitution (NDIS) provide a direct means to probe the structure of a complex fluid mixture. The method is easily extended to studies under non-ambient conditions for which large sample containers can be used to withstand temperatures of up to and pressures of 2000 bar. Within the past few years NDIS experiments have been performed on aqueous solutions of several salts at temperatures up to and beyond their critical states. The results show that both the aqua ion and hydrogen bond structure change appreciably with increases in temperature.


Platelet concentrates (PC) were stored for 7 days at 22°C in either CPDA-1 plasma (control) or one of three plasma-free media, namely a Tyrodes solution (BTST) fortified with citrate and with additional phosphate for buffering effect; Plasma-Lyte A solution (PCD) fortified with dextrose and citrate; and Ringers/CPD-50 (10:1) solution (RCPD) buffered with phosphate, all with a pH of 7.4. Parameters monitored included platelet count, pH, hypotonic shock response, aggregation response to single and paired agonists, and release by platelets of endogenous LDH, ATP and 5HT. BTST was shown to be a satisfactory plasma substitute over the entire storage period. PCD gave similar results over 4 days, although the decrease in pH was more marked. In all test systems RCPD was shown to be a poor plasma substitute.


Previous work has shown that an abdominal trauma index (ATI) based on anatomic severity of injury reliably predicts complications following abdominal trauma, whereas the Prognostic Nutritional Index (PNI) does not. This study was undertaken to reconcile the disparity between the PNI and ATI as predictors of postoperative morbidity and mortality. Twenty-four patients undergoing immediate laparotomy following acute abdominal trauma were evaluated. Their mean age was 32.8 years (range 18-59 years); 18 were men. All patients underwent nutritional assessment within 12 hours of surgery. A statistical comparison of blood replacement, operating time, ATI, and PNI was performed. The mean PNI was 51 and mean blood replacement was 12.5 units. Using linear regression the PNI and amount of blood replacement correlated significantly (r = 0..44, p less than 0.05). Operating time and ATI did not correlate with PNI. In conclusion, the PNI was more strongly influenced by blood loss than severity of intraperitoneal injury. For this reason it is relatively ineffective in predicting complications following trauma.


Today, since the contemporary world is changing to meet the needs of various people, the aim should be to provide a condition for areas and buildings in order to respond to the needs of various shapes, its future audience requirements, adaptability, flexibility, versatility, etc. Since the scarcity of environmental resources and ecological crises in the world today cannot justify the demolition and reconstruction of areas is more important. So areas should be designed in such a way to compliance with the contemporary needs. Moreover, it can be adaptive to its future audience. The method used in this research is descriptive-analysis collected using questionnaires and library tools and the software SPSS and factor analysis to analyze to express the characteristics and the reliance of each one. The results show that between the effective factors on the admissibility of space users, flexibility has the greatest impact on Adaptability and also its sub-variable (ranging versatility) has the greatest impact on flexibility of the place, and after that, fluidity factors, scalability, flexibility, and eventually, convertibility has had impact in monument of Bu-Ali which is located in Hamedan city Subsequently and convertibility is the least factor influencing the flexibility in monument of Bu-Ali in Hamedan.