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text: BIO 315 – 001 Introduction to Cell Biology Dept of Biology College of Arts and Sciences Class: 10:00-10:50 Monday, Wednesday and Friday BS 116 Instructor: S. Steiner Office: BS 319A Telephone: 257-3870 e-mail: [email protected] - I will try to respond to any questions by e-mail in a timely manner. Preferred method of contact. TA: TBA Office Hours: I will meet with you whenever you need help and the times for the meetings can be arranged by e-mail, or before or after class. In addition, I will be available after each lecture. Text: Cell and Molecular Biology- concepts and experiments –6th edition ed. -Gerald Karp Course Description: The structure and function of cells will be considered. Emphasis will be placed on the ultrastructure of cell organelles in plants and animals as a framework for understanding the compartmentalized nature of cell activity.Lecture, 3 hours, laboratory 3 hours/weekly Course overview and objectives Lecture: To familiarize upper level students to the fundamental principles of eukaryotic cell biology at the molecular and cytological level with particular emphasis on biochemical and cytological approaches and mechanisms. The subjects to be mastered include: structure and function of the plasma membrane, transport of small molecules, ions and macromolecular complexes across membranes, protein trafficking, the cytoskeleton, signal transduction pathways, and the control of cell division and cellular proliferation. Lab: The laboratory component of this course is designed to give upper division majors an opportunity to learn modern techniques used in cell biology research . Students will master the fundamentals of microscopy (e.g., light, fluorescent, confocal). Students will isolate various subcellular components, e.g., nuclei, mitochondria, lysosomes, and will characterize these organelles by microscopy, enzyme assays, protein gels and antibody labeling. Additional cell structure (cytoskeletal elements) and function (mitosis) will be explored. 1 Learning Outcomes; Students will be able to: 1) Demonstrate an understanding of basic cell structure at molecular levels; 2) Describe the structure of cell components and relate that structure to their functions and to cellular activities as a whole, and demonstrate how cell fractionation is used to isolate these components ; 3) Describe the processes involved in cell division; 4) Describe how cells obtain energy, and how they use energy for driving reactions within the cell; 5) Demonstrate a range of appropriate and relevant experimental techniques and how they are used; 6) Conduct an experiment accurately, report and interpret the results in an appropriate manner. Attendance: Web site: http://www.as.uky.edu/academics/departments_programs/Biology/ Biology/faculty_research/faculty/steiner Prior to lecture I will post a preliminary copy of the lecture notes. These notes will lack the news articles that I present each lecture and any updating that I do just before lecture. Before each examination I will post a final version of the notes A significant amount of the lecture material will be taken from current articles in journals, newspapers, and magazines and therefore will not be in the text. Additionally, during the lecture several topics from the notes will be elaborated upon and at least 5 questions per exam will come from the elaborated topics (the material will not necessarily be explicitly in the notes). I have done this in the past and during the exams student who do not attend lecture wonder about the basis for some of the questions. Consequently, class attendance is highly recommended Grades: Grades will be based on your performance on the following activities: Lecture: EXAM 1 = 100 PTS EXAM 2 = 100 PTS EXAM 3 (FINAL) = 100 PTS Each exam is worth 33% of the lecture component of your grade grade; the class mean for each exam will be adjusted upward to 72% if needed. Although each examination will only cover the lecture material for that segment of the course you are responsible for the relevant material covered in earlier lectures (that is, much of the material in later chapters depends on material in earlier chapters). Laboratory: You will be required to submit a written report of each of the laboratory activities ,II - X listed in the laboratory schedule. Each report is due the class period 2 immediately following the completion of the laboratory exercise. Details on the format for each report will be given in lab. This component of your grade will be worth 100 points. Final grades will be based on the combination of your lecture and laboratory scores and will be determined as follows: 100-90 = A; 89-80 = B; 79-70 = C; 69-60 = D; <60 = E. Examination schedule: Examination 1: October 1 Examination 2: November 5 Examination 3: December 15th- 8:00 a.m. Midterm Grades will be available by October 4, 2010 and are based on the grading scheme detailed above. Individuals that miss an examination will be given a zero unless they have an official excuse. Individuals who will miss an examination because of an official school function (members of the band, debate team, and religious holiday) should contact the instructor immediately before the examination date in order to schedule a make-up. Those missing an examination because of illness should contact the instructor immediately after the examination date or as soon as possible to schedule a make-up examination. UNIVERSITY POLICY ON EXCUSED AND UNEXCUSED ABSENCES The following are acceptable reasons for excused absences: 1. serious illness of student (doctor's note required) 2. illness or death of family member (doctor's note required) 3. University - related trips (such as to a football game for a team member or band member, official note required) 4. Major religious holidays. Students MUST notify instructor IN WRITING of all such holidays to assure being excused. ABSENCE FROM LABORATORY, MISSED REPORTS If you miss a laboratory meeting, or fail to hand in a lab report you will lose the points associated with these. If you want credit for these omissions, you must contact your TA within three calendar days of the omission and present your TA with a doctor's note also within 3 calendar days of the omission. Disabilities: If you have a documented disability that requires academic accommodations, please see me as soon as possible during scheduled office hours. In order to receive accommodations in this course, you must provide me with a Letter of Accommodation from the Disability Resource Center (Room 2, Alumni Gym, 257‐2754, email address ([email protected]) for coordination of campus disability services available to students with disabilities. Course Policy on Classroom Civility and Decorum: 3 The university, college and department all have a commitment to respect the dignity of all and to value differences among members of our academic community. There exists the role of discussion and debate in academic discovery and the right of all to respectfully disagree from time-to-time. Students clearly have the right to take reasoned exception and to voice opinions contrary to those offered by the instructor and/or other students (S.R. 6.1.2). Equally, a faculty member has the right -- and the responsibility -- to ensure that all academic discourse occurs in a context characterized by respect and civility. Obviously, the accepted level of civility would not include attacks of a personal nature or statements denigrating another on the basis of race, sex, religion, sexual orientation, age, national/regional origin or other such irrelevant factors. Academic Offenses PLAGIARISM and CHEATING are serious academic offenses. The following is an excerpt taken from the "Students Rights and Responsibilities Handbook, University of Kentucky" regarding cheating. "Cheating is defined by its general usage. It includes, but is not limited to, the wrongful giving, taking, or presenting any information or material by a student with the intent of aiding himself/herself or another on any academic work which is considered in any way in the determination of the final grade." The following is an excerpt taken from the "Students Rights and Responsibilities Handbook, University of Kentucky" regarding plagiarism. "All academic work, written or otherwise, submitted by students to their instructors or other academic supervisors, is expected to be the result of their own thought, research, or self-expression. When students submit work purporting to be their own, but which in any way borrows ideas, organization, wording or anything else from another source without appropriate acknowledgment of the fact, the students are guilty of plagiarism. Plagiarism includes reproducing someone else's work........ If the words of someone else are used, the student MUST put quotation marks around the passage in question and add an appropriate indication of its origin. Making simple changes while leaving the organization, content and phraseology intact is plagiaristic." Charges of an academic offense will be made against any student that cheats or commits plagiarism. Penalties for such an offense will be assessed according to University Regulations regarding Academic Offenses. The most severe penalties include suspension or dismissal from the University. I have a zero-tolerance policy regarding academic offenses. 4 Outline of Course Content Lecture Schedule Topics Reading Introduction to the study of cell and molecular biology Chapter 1 The chemical basis of life Chapter 2 Bioenergetics, enzymes and metabolism Chapter 3 The structure and function of the plasma membrane Chapter 4 Cell signaling and signal transduction: communication between cells Chapter 15 Aerobic respiration and the mitochondrion Chapter 5 Interactions between cells and their environment Chapter 7 Cytoplasmic membrane systems: structure, function and membrane trafficking Chapter 8 The cytoskeleton and cell motility Chapter 9 The nature of the gene and the genome Chapter 10 Gene Expression: From transcription to translation Chapter 11 The cell nucleus and the control of gene expression Chapter 12 DNA replication and repair Chapter 13 Cellular reproduction Chapter 14 Cancer Chapter 16 Techniques in cell and molecular biology Chapter 18 5 Laboratory Content / Schedule: I. Microscopy a. light microscopy b. fluorescent microscopy c. confocal microscopy II. Subcellular fractionation- chicken liver (total of 3 weeks-exercises II, III, IV) III. A Purfication of mitochondria by differential sedimentation and monitoring of cell fractions for specific activity of succinate dehydrogenase. IV. Enzymology laboratory- Learn the basics of enzymological assays. V. Western blot analysis coupled with microscopy- apoptotic versus nonapoptotic (total of 2 weeks) VI. In Vivo Visualization of subcellular components by microscopy (confocal) (total of 3 weeks- VI, VII) VII. Studies of the cytoskeletal system a. tubulin (immunostaining and in vitro assembly) b. actin (immunostaining and in vitro assembly) c. GFP- tubulin (in vivo labeling in Drosophila embryo) VIII. Early embryo development and regeneration with Axolotl – total of 3 weeks IX. Studies of nuclear and chromosome structure and histone modifications X. Mitosis/meiosis- onion root tip and in vivo tubulin-GFP labeling in Drosophila cell cycle mutants. (total of 2 weeks) 6


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Ricardo Canales
Ricardo Gabriel Canales Lanza (born 30 May 1982) is a Honduran footballer who currently plays for C.D.S.Vida in the Honduran National Football League as a goalkeeperContents1 Club career 2 International career 3 Honours 4 References 5 External linksClub career[edit] Nicknamed el Gato (The Cat), Canales made his debut in league on 16 May 2001 playing for Victoria against Real España. He was released from Motagua just after he returned from playing with the Honduras
Honduras national football team in the 2010 FIFA World Cup
2010 FIFA World Cup in South Africa[1] and he returned to Victoria.[2] In July 2011 he signed for Atlético Choloma,[3] and after two years of participation the club was regulated to Liga Nacional de Ascenso de Honduras. In the year 2013 he rejoined F.C. Motagua
F.C. Motagua on a one-year contract in which he only completed the Apertura tournament.[4] He signed for C.D.S
|"Ricardo Canales" on:
La Ceiba
La Ceiba
Ceiba (Spanish pronunciation: [la ˈseiβa]) is a port city on the northern coast of Honduras
Honduras in Central America. It is located on the southern edge of the Caribbean, forming part of the south eastern boundary of the Gulf of Honduras. With an estimated population of over 200,000 living in approximately 170 residential areas[2] (called colonias or barrios), it is the third largest city in the country and the capital of the Honduran department of Atlántida. La Ceiba
Ceiba was officially founded on 23 August 1877. The city was named after a giant ceiba tree which grew near the old dock. The dock itself finally fell into the sea in late 2007. The city has been officially proclaimed the "Eco-Tourism Capital of Honduras" as well as the "Entertainment Capital of Honduras"
|"La Ceiba" on:
Real C.D. España
Real Club Deportivo España, Real España, or simply España is a Honduran football club, which currently plays in the Liga Nacional
Liga Nacional de Honduras. They are based in San Pedro Sula, Cortés, and their home venue is the Estadio Francisco Morazán.Contents1 History 2 Colours and badge 3 Stadium 4 Club Rivalries4.1 Clásico Moderno (Honduras) 4.2 Clásico Sampedrano 4.3 Motagua– Real España
|"Real C.D. España" on:
Coordinates: 15°00′N 86°30′W / 15.000°N 86.500°W / 15.000; -86.500 Republic
Republic of Honduras República de Honduras (Spanish)FlagCoat of armsMotto: "Libre, Soberana e Independiente" (Spanish) "Free, Sovereign and Independent"Anthem: "Himno Nacional de Honduras" "National Anthem of Honduras"Capital and largest city Tegucigalpa 14°6′N 87°13′W / 14.100°N 87.217°W / 14.100; -87.217Official languages SpanishEthnic groups ([1])90% Mestizoa 7% Amerindian 2% Black 1% WhiteDemonymHonduran C
|"Honduras" on:
International Olympic Committee International Football
Football Association BoardStaff103Website www.fifa.comThe Fédération Internationale de Football
Football Association (FIFA /ˈfiːfə/ FEEF-ə; French for " International Federation of Association Football") is an association which describes itself as an international governing body of association football, futsal, and beach soccer. FIFA
FIFA is responsible for the organization of football's major international tournaments, notably the World Cup which commenced in 1930 and the Women's World Cup which commenced in 1991. FIFA
FIFA was founded in 1904 to oversee international competition among the national associations of Belgium, Denmark, France, Germany, the Netherlands, Spain, Sweden, and Switzerland. Headquartered in Zürich, its membership now comprises 211 national associations
|"FIFA" on:
2007 Copa Interclubes UNCAF
The 2007 UNCAF Interclub Cup was the 25th edition of the international club football competition held in the UNCAF region representing the seven nations of Central America. C.D. Motagua obtained their first regional title.[1] This was the ninth year of the current format using the name UNCAF Interclub Cup. The tournament was also be a qualifying event for the 2008 CONCACAF Champions' Cup. The top three finishers in the tournament qualified for the 2008 CONCACAF Champions' Cup. The official draw took place on June 19 in Guatemala
|"2007 Copa Interclubes UNCAF" on:
2009 CONCACAF Gold Cup
The 2009 CONCACAF Gold Cup
CONCACAF Gold Cup was the tenth edition of the CONCACAF
CONCACAF Gold Cup competition, and the twentieth soccer championship of North America, Central America
Central America and the Caribbean (CONCACAF). It was contested from 3 July to 26 July 2009 in the United States.[1] This competition was the fourth tournament without guests from other confederations. Mexico
Mexico won their fifth Gold Cup, and eighth CONCACAF Championship overall, after beating the United States
United States 5–0 in the final
|"2009 CONCACAF Gold Cup" on:
Panama National Football Team
The Panama
Panama national football team (Spanish: Selección de fútbol de Panamá) represents Panama
Panama in international football. The team is controlled by the governing body for football in Panama, Panamanian Football Federation, which is a member of CONCACAF
CONCACAF and the regional UNCAF
|"Panama National Football Team" on:
Liga Nacional De Ascenso De Honduras
Liga de Ascenso (Promotion League) is the second division of Honduran football; it was founded on 17 December 1979 as Segunda División (Second Division) and renamed Liga de Ascenso (Promotion League) on 21 July 2002.[1] The league is divided into 4 groups: Zona Norte y Atlántica (North and Atlantic Zone), Zona Norte y Occidente (North and West Zone), Zona Centro y Sur (Central and South Zone), Zona Sur y Oriente (South and East Zone). The top 2 teams of each group qualifies for the liguilla (play-offs). Each season is divided into two tournaments, apertura (opening) and clausura (closing). The champion of the opening and closing tournament, compete for the promotion to Liga Nacional de Fútbol de Honduras
Honduras in a two-legged match. Two teams are relegated to Liga Mayor de Futbol de Honduras
|"Liga Nacional De Ascenso De Honduras" on:
South Africa
[Note 1]11 languagesAfrikaans Northern Sotho English Southern Ndebele Southern Sotho Swazi Tsonga Tswana Venda Xhosa ZuluEthnic groups (2014[3])80.2% Black 8.8% Coloured 8.4% White 2.5% AsianReligion See Religion in South AfricaDemonym South AfricanGovernment Unitary dominant-party parliamentary constitutional republic• PresidentCyril Ramaphosa• Deputy PresidentDavid Mabuza• Chairperson of the National Council of ProvincesThandi Modise• Speaker of the National AssemblyBaleka Mbete• Chief JusticeMogoeng MogoengLegislature Parliament• Upper houseNational Council• Lower houseNational AssemblyIndependence from the United Kingdom• Union31 May 1910• Self-governance11 December 1931• Republic31 May 1961•
|"South Africa" on:
2010 FIFA World Cup
The 2010 FIFA World Cup
FIFA World Cup was the 19th FIFA
FIFA World Cup, the world championship for men's national association football teams. It took place in South Africa
South Africa from 11 June to 11 July 2010. The bidding process for hosting the tournament finals was open only to African nations. In 2004, the international football federation, FIFA, selected South Africa over Egypt and Morocco
Morocco to become the first African nation to host the finals.[citation needed] The matches were played in 10 stadiums in nine host cities around the country,[5] with the opening and final played at the Soccer City stadium in South Africa's largest city, Johannesburg.[6][7] Thirty-two teams were selected for participation[8] via a worldwide qualification tournament that began in August 2007
|"2010 FIFA World Cup" on:
Friendly Match
An exhibition game (also known as a friendly, a scrimmage, a demonstration, a preseason game, a warmup match, or a preparation match, depending at least in part on the sport) is a sporting event whose prize money and impact on the player's or the team's rankings is either zero or otherwise greatly reduced. In team sports, matches of this type are often used to help coaches and managers select and condition players for the competitive matches of a league season or tournament. If the players usually play in different teams in other leagues, exhibition games offer an opportunity for the players to learn to work with each other
|"Friendly Match" on:
Liga Nacional De Fútbol Profesional De Honduras
Liga Nacional de Fútbol Profesional de Honduras
Honduras (Honduran National Professional Football League) is the first and highest division of football in Honduras. The league season is divided into Opening (autumn) and Closing (spring). One team is relegated to the Liga de Ascenso (the team with fewest points in Opening and Closing) and one team is promoted from Liga de Ascenso. The first 4 clubs participate in play-offs to decide the champion.[1] The winners of the Opening and Closing competitions participate in the CONCACAF
CONCACAF Champions League.[2] [3]Contents1 History of the League 2 2017–18 teams 3 Current Format 4 Relegation-Promotion 5 Historic5.1 All Time Scorers 5.2 Statistics (1965–66 – present)6 Champions by year 7 Titles by club 8 In International competitions 9 See also 10 References 11 External linksHistory of the League[edit] In the 1930s, football experienced a surge in popularity in the country
|"Liga Nacional De Fútbol Profesional De Honduras" on:
Goalkeeper (association Football)
Goalkeeper, often shortened to keeper or goalie, is one of the major positions of association football. It is the most specialised position in the sport. The goalkeeper's primary role is to prevent the opposing team from successfully moving the ball over the defended goal-line (between the posts and under the crossbar). This is accomplished by the goalkeeper moving into the path of the ball and either catching it or directing it away from the vicinity of the goal line. Within the penalty area goalkeepers are able to use their hands, making them (outside throw-ins) the only players on the field permitted to handle the ball. The back pass rule prevents goalkeepers handling direct passes back to them from teammates. Goalkeepers usually perform goal kicks, and also give commands to their defense during corner kicks, direct and indirect free kicks, and marking
|"Goalkeeper (association Football)" on:
A surname, family name, or last name is the portion of a personal name that indicates a person's family (or tribe or community, depending on the culture).[1] Depending on the culture all members of a family unit may have identical surnames or there may be variations based on the cultural rules. In the English-speaking world, a surname is commonly referred to as a last name because it is usually placed at the end of a person's full name, after any given names. In many parts of Asia, as well as some parts of Europe
Europe and Africa, the family name is placed before a person's given name. In most Spanish-speaking and Portuguese-speaking countries, two surnames are commonly used and in some families that claim a connection to nobility even three are used. Surnames have not always existed and today are not universal in all cultures. This tradition has arisen separately in different cultures around the world
|"Surname" on:
Spanish Naming Customs
Spanish naming customs
Spanish naming customs are historical traditions for naming children practised in Spain. According to these customs, a person's name consists of a given name (simple or composite) followed by two family names (surnames). The first surname is usually the father's first surname, and the second the mother's first surname. In recent years, the order of the surnames can be decided at birth. Often, the practice is to use one given name and the first surname only (e.g. Miguel de Unamuno), with the full name being used in legal, formal, and documentary matters, or for disambiguation when the first surname is very common (e.g. Federico García Lorca). [1]. In these cases, it is common to use only the second surname, as in "Lorca" or "Zapatero"
|"Spanish Naming Customs" on:


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Amid grumbles that they had not done much in the first quarter of their tenure, Nyanza governors who survived election petitions have now set out to initiate development projects.
Save for Homa Bay Governor Cyprian Awiti whose election was nullified by the court, his counterparts, Cornell Rasanga (Siaya), Prof Anyang' Nyong'o (Kisumu), John Nyangarama (Nyamira), James Ongwae (Kisii) and Okoth Obado (Migori) won petitions against them.
Mr Awiti however, remains in office after he filed an intention to appeal against the ruling.
Prof Nyong'o is serving his first term while the other governors are on the last leg of their two-term tenure.
In separate interviews with the Sunday Standard yesterday, the governors pledged to fulfill election pledges.
The county bosses have prioritised agriculture, healthcare and water projects and plan to increase budgetary allocations for the same.
Kisumu county Government has embarked on relocation of Kachok dumpsite, which has been an eyesore.
Stay informed while on the go by subscribing to the Standard Group SMS service. Text the word 'NEWS' to 22840.
Pay for the beneficiaries
Mr Rasanga, who rode to power on the back of promises to complete development projects said that with the petitions headache behind him he is now ready to work.
As part of efforts to make healthcare affordable, the Siaya governor is pushing to ensure the elderly and expectant women are under the National Health Insurance Fund (NHIF) cover.
The county will pay for the beneficiaries the minimum NHIF Sh500 premium.
Rasanga said he was already in talks with the World Food Programme and the Kenya Commercial Bank to facilitate commercialisation of sorghum farming in the county, to supply the Kenya Breweries Limited factory in Kisumu.
To boost food security the Siaya county Government has set aside Sh70 million to support irrigation in Uyoma, Rarieda and Alego Usonga sub-counties.
"We have realised that we can no longer rely on erratic rainfall and we are not going to let lack of water limit our agricultural potential, we want to pump money into irrigation so that we can achieve food security," he said.
Kisii Governor Ongwae is lobbying senators to approve the proposal for the establishment of a sugar factory in the county.
The proposed Sh5 billion factory will also produce electricity to power local industries.
The governor is expected to commission construction of the Sh2 billion cancer screening, treatment and management centre to serve the region.
The centre will compliment the Kisii Level 6 hospital as a teaching and referral facility.
This will be the their biggest cancer centre in the country after Kenyatta and Moi Teaching and Referral Hospitals, although there are plans by the national Government to construct facilities in Kisumu and Naivasha.
Ongwae disclosed that the county Government received financial aid from the Arab Bank and the Saudi government towards construction of the cancer centre.
He said once complete the facility will ease the strain on referral hospitals.
"In my first term, I concentrated on making Kisii District Hospital a referral facility.
"Now my focus is on ensuring that all health facilities are up and running, fully equipped and staffed so that residents can access universal healthcare at any facility near them," he pledged.
He said Sh415 million has been set aside for road construction and they county will also utilise the fuel levy to fund the project.
"Kisii is largely an agricultural town and we want to open up the road network to ensure the produce gets to the various markets.
"But because the roads are prone to destruction by rain, we want to elevate standards so that the farmers and traders are not affected," he said.
Overhaul the sewer system
"There are also village roads which we started doing in the first term but did not finish, others are already damaged and in need of repair. We have set aside Sh360 million to see that contractors are on site and another Sh100 million in fuel levy."
The governor also disclosed plans to overhaul the sewer system in Kisii after securing a deal with a German firm that will address water problem.
"Despite being blessed with abundant rainfall, we have not sufficiently retained the resource to ensure accessible supply, especially for domestic use." He announced plans to sink boreholes and pump water to surrounding schools and homes.
Nyamira Governor Nyangarama plans to prioritise health, agriculture, water provision, conservation of water towers, waste management, electrification and the construction of a new county headquarters.
He wants to increase uptake of NHIF cover from the current 17 per cent of the population to 60 per cent. This, he said, would bolster the Linda Mama programme which seeks to ensure mothers deliver babies in health facilities.
The county Government has upgraded the Nyamira District Hospital to a referral facility.
"We want to go ahead and establish a 12-bed children's ICU (intensive care unit) ward," he said.
Nyangarama said he had opened talks with a Finnish waste-to energy company to help convert the 300 tonnes of waste produced everyday into electrical energy to light up the county from the current 49 per cent and add the rest to the national grid.
The county is also seeking to partner with Kenya Power to boost electrification of homes.
Nyangarama said Sh60 million grant secured from the World Bank would go towards extension services to farmers to spur commercial farming.
And Migori Governor Obado plans to complete a road that seeks to decongest Migori town, improve healthcare services, and agricultural production.
The county boss who is the Council of Governors' agriculture committee chairman said plans were underway to establish a sweet potato factory in a bid to boost value addition of the produce.
The county Government also plans to set up a fish cooling plant in Muhuru Bay to eradicate wastage.


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Richie Furay
Sept. 30, 2016
The Katharine Hepburn Cultural Arts Center
Richie Furay and friends entertained an intimate audience at the Katharine Hepburn Cultural Arts Cents, also known as "The Kate". Richie helped shape the sound of country rock and folk as we know it today and is known the world over as one of the greats in the early rock scene. A founding member of Buffalo Springfield, Poco, and the Souther,Hillman Furay band, his voice is instantly recognizable.
Furay gave a wonderful performance on September 30th. He started the evening off letting the audience know this was going to be a relaxed performance. Kind of like a gathering in his living room for a evening with friends. It indeed felt like a big living room as the Kate holds only about 250 patrons. It also was a pared down version of his band. He began the evening by himself. Then as the evening progressed introduced his daughter Jessie Furay Lynch who sang harmony beautifully. Scott Sellen joined in after that and played guitar and banjo. Finishing out the quartet Jack Jeckot joined them on keyboard and harmonica.
Richie spoke about the influence other artists have had on his career and how they helped in the evolution of his music. He performed Dan Fogelberg's song "Don't Lose Heart" accompanied by his daughter Jessie Furay Lynch on harmony.
The informal show was very well performed and it suited the Kate. Being a small venue Furay was able to easily interact with the audience. It was a very enjoyable evening.
Richie Furay (Lead Vocals and Guitar)
Jessie Furay Lynch (Harmony and Lead Vocals)
Scott Sellen (Lead Guitars, Banjo, Keyboard)
Jack Jeckot (Keyboards, Harmonica, Vocals)
Opening for Richie Furay was the Chris Berardo & The DesBerardos Acoustic Trio.
Chris Berardo, his brother Marc Berardo and Billy Kelly warmed up the crowd. They played a few songs off their "Ignoring All the Warning Signs" album along with the single "Somebody Like Me".
Review by Donna Erichsen
Photos by George Bekris


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Wayfair Bathroom Storage Cabinets
Wayfair Bathroom Storage Cabinets | People have a tendency to own plenty of "stuff", which "stuff" has a tendency to stack up, clutter and exist in one pile in a certain room. New and improved wall storage systems might help improve this disorderly situation in a short time. Even small rooms like the bathroom can be messy and cluttered, but small bathroom self storage and different storage container might help to organize any big or small space. Organization is not a must, however it is nice to be able to start to see the floors with your bedroom or even the countertops with your bathroom or kitchen once in a while. Organizing is effortless when you can effectively utilize power tools.
The best way to secure a good start on organizing your belongings is usually to focus on quicks tools. First, you may need a large trash bag, a rubbish bin, and maybe a couple of cleaning gloves, just in case. You should then go through the room and initiate removing something that either are afraid or don't use. These types of items might cause clutter for being overwhelming, in addition to their presence is pointless. Items especially like old rubbish bin definitely be cleaned along with old stuff that are broken too. In closets especially, this process works because stuff that do not fit or happen to be ruined can definitely be given away or donated at the same time.
See also: Vintage Tub Faucets
This is the one other good point, as an alternative to wasting your clutter, additionally, it can certainly be a wise decision to donate it with a local charity, or perhaps a Salvation Army to help those who work in need. Certain such things as clothes shoes or something that you are afraid anymore can all be donated to charity. This is ideal for organization because not simply will your living area look better, nevertheless, you yourself will feel great as you have accomplished something beneficial to another individual at the same time.


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Featured Content
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Neuromodulation of lumbosacral spinal networks enables independent stepping after complete paraplegia
In a human subject with chronic paraplegia, a combination of epidural electrical stimulation and long-term rehabilitative training have culminated in the first report of unassisted, voluntary independent stepping in a paralyzed individual.
World View |
No more first authors, no more last authors
If we really want transdisciplinary research, we must ditch the ordered listing of authors that stalls collaborative science, says Gretchen L. Kiser.
Books & Arts |
Genetic determinism rides again
Nathaniel Comfort questions a psychologist's troubling claims about genes and behaviour.
Nature Briefing |
Daily briefing: India, China, Saudi Arabia and the United States will lose most from climate change
The top countries set to lose out economically from climate change, how to tag a billion plankton pictures and a call to ditch the ordered listing of authors.
Latest Research
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Architecture of the TRPM2 channel and its activation mechanism by ADP-ribose and calcium
Structures of the transient receptor potential melastatin 2 channel in the apo resting (closed) state and in the ADP-ribose/Ca2+-bound active (open) state are determined by cryo-electron microscopy.
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The interaction landscape between transcription factors and the nucleosome
A method for systematically exploring interactions between the nucleosome and transcription factors identifies five major interaction patterns.
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Discovery of a periosteal stem cell mediating intramembranous bone formation
A periosteal stem cell specialized in intramembranous bone formation has been identified and was found to be essential for normal bone development and fracture healing.
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Integrated lithium niobate electro-optic modulators operating at CMOS-compatible voltages
Chip-scale lithium niobate electro-optic modulators that rapidly convert electrical to optical signals and use CMOS-compatible voltages could prove useful in optical communication networks, microwave photonic systems and photonic computation.
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Glider soaring via reinforcement learning in the field
A reinforcement learning approach allows a suitably equipped glider to navigate thermal plumes autonomously in an open field.
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Hydraulic diversity of forests regulates ecosystem resilience during drought
The diversity in the hydraulic traits of trees mediates ecosystem resilience to drought and will probably have an important role in future ecosystem–atmosphere feedback effects.
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T cells in patients with narcolepsy target self-antigens of hypocretin neurons
The detection of hypocretin-specific autoreactive CD4+ and CD8+ T cells in patients with narcolepsy reveals the autoimmune aetiology of this disorder.
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Superstructures generated from truncated tetrahedral quantum dots
Truncated tetrahedral nanocrystals can self-assemble into one-, two- and three-dimensional superstructures.
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Tc toxin activation requires unfolding and refolding of a β-propeller
A high-resolution cryo-electron microscopy structure of a complete Tc holotoxin complex reveals the precise mechanism of Tc toxin assembly, gate opening and release of the cytotoxic enzyme into the translocation channel.
Latest Reviews & Analysis
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From the archive
What Nature was saying 50 and 100 years ago.
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Elimination of senescent cells prevents neurodegeneration in mice
Aggregation of the protein tau is implicated in neurodegenerative diseases in humans. It emerges that eliminating a type of damaged cell that no longer divides can prevent tau-mediated neurodegeneration in mice.
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A core problem in nuclear assembly
Chromosomes can exist outside the nucleus in rupture-prone structures called micronuclei. It emerges that micronuclei are fragile because their outer layer lacks some nuclear-envelope components.
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Timing the action of light on matter
Photoemission, the ejection of an electron from a material on the absorption of a photon, is one of the fastest processes in nature. An experiment demonstrates how the dynamics of this process can be captured in real time.
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Put to sleep by immune cells
The sleep disorder narcolepsy is linked to immune-system genes and is caused by the loss of neurons that express the protein hypocretin. Hypocretin-targeting immune cells have now been found in people with narcolepsy.
News & Views |
Short proton bunches rapidly accelerate energetic electrons
Experiments show that short bunches of protons can produce electric fields that are strong enough to accelerate energetic electrons compactly. This discovery could lead to miniaturized high-energy particle accelerators.
News & Comment
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Brexit is already damaging European science
With six months to go, uncertainty posed by the decision to leave the European Union is taking its toll.
News Feature |
Six months to Brexit: how scientists are preparing for the split
Seven researchers and campaigners tell Nature how Britain's break-up with the EU is affecting research.
Career Feature |
The quest for postdoctoral independence
How to step out from the shadow of your principal investigator.
World View |
No more first authors, no more last authors
If we really want transdisciplinary research, we must ditch the ordered listing of authors that stalls collaborative science, says Gretchen L. Kiser.
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Yellowstone grizzly bears back under endangered-species protections
Judge rules that the US government didn't consider the best available science when it removed the animals from the endangered-species list.
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The costs of climate inaction
A new analysis breaks down the likely social cost of carbon emissions by country and should make unhappy reading for politicians.
Nature Outlook
Alzheimer's disease
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CELLECTIS Inc.
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The University of Texas at Austin
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Yale University
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Texas Tech University Health Sciences Center El Paso
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Duke University
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Dynamo Confidence Staggered by New YorkHouston found no consolidation in the Eastern Conference in home loss
by David Ruiz | Monday, September 09, 2013
HOUSTON – The Houston Dynamo has extended its negative streak after several tough away matches.
And New York Red Bull confirmed their superiority through a devastating offensive attack in the 2nd half of the game and obtained its 1st victory 4-1 at BBVA Compass Stadium.
After an even match in the 1st half, the Dynamo regretted a few goal opportunities to lead the game and also to gain the confidence needed to confront a powerful team. Houston's strikers are still having difficulties to find the net and the opponents are making them to pay their mistakes.
This time, the New York team deployed their destructive arsenal and scored 3 amazing goals in the 2nd half commanded by Thierry Henry, who is not as fast as he used to be, but his talent can be seen every time the French touches the ball and create opportunities for their teammates.
ANALYSIS: In the last 4 games, the Dynamo has had trouble resisting their opponents until the final whistle. During the 1st half, the Dynamo showed the team was able to defend and comeback after Eric Alexander goal in the 14th minute. The equalizer came in charge by the Oranges with the participation of the Honduran player Alex Lopez, who chipped outside the foot and Jason Johnson slipped it home for his 1st MLS goal, and 1st assist for Lopez, respectively.
Houston's efforts to get a good result were vanished in the opening minutes of the 2nd half when Henry dribbled the middle of the defense and slotted it past Tally Hall. In this occasion, Alexander, Henry, Jonny Steele and Lloyd Sam shattered the Orange defense where some players were put in the spot. For example, Will Bruin has been criticized in the last games by missing several goal chances.
However, the Dynamo are looking forward to make some changes and give the opportunity to other talented players who are able to offer other alternatives such as Chabala, Johnson, Lopez and the return of Brian Ching. In addition, it is a matter of concern that the Dynamo has received 12 goals in the last four games, so the defense training needs to be done.
POSITIVE: Alex Lopez and Jason Johnson showed their skills.
NEGATIVE The defense is conceding too many goals and the forwarders are missing crucial opportunities.
NEXT UP: September 14 – Philadelphia Union vs. Houston Dynamo, PPL Park, Chester, Pa. 7:30 p.m. EST, MLS Live.


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Pulse foundation seeks answers for club's future
Should the site of Pulse nightclub be torn down or a memorial created in the current space? And should it be a place to celebrate love or mourn those lost? Those questions are part of a new survey.
Copyright © 2018, Orlando Sentinel


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McALLEN, Texas (AP) — First lady Melania Trump boarded a flight to a facility housing migrant children separated from their parents wearing a jacket that read "I really don't care, do u?"
The green hooded spring military jacket has the words written graffiti-style on the back.
When asked what message the first lady's jacket intended to send, spokeswoman Stephanie Grisham said: "It's a jacket. There was no hidden message."
FLOTUS spox confirms Mrs. Trump wore a jacket to visit border kids that reads: "I really don't care. Do you?" Spox says: "It's a jacket. There was no hidden message. After today's important visit to Texas, I hope the media isn't going to choose to focus on her wardrobe." pic.twitter.com/Bp4Z8n455G— Jim Acosta (@Acosta) June 21, 2018
Mrs. Trump wore a different pale yellow jacket when the plane landed in McAllen, Texas, for a visit to the Upbring New Hope Children's Center, which houses 55 migrant children.
The youthful jacket sharply contrasts with the first lady's typically bold, foreign-flavored wardrobe. In public appearances, the first lady has worn designs by Dolce & Gabbana, Del Pozo, Christian Dior, Emilio Pucci, Givenchy and Valentino, often with daringly high Christian Louboutin heels.


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$955—$1,300 1—3 bed N. Litchfield Road, Surprise AZ, 85374
Previously Listed from $955 1—3 bed
N. Litchfield Road, Surprise, 85374
Commute to Downtown Sun City West
This apartment is in Surprise. Nearby parks include DreamCatcher Park and Centennial Friendship Park.
La Borgata Apartments has a Walk Score of 48 out of 100. This location is a Car-Dependent neighborhood so most errands require a car.
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Surprise, Arizona, 85374
Most errands require a car.
About your score
Explore how far you can travel by car, bus, bike and foot from La Borgata Apartments.
Bus lines:
571 Surprise Express
0.7 mi
View all Surprise apartments on a map.
Popular apartment searches include pool, furnished and fireplace.
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La Borgata Apartments is in the city of Surprise, AZ. Surprise has an average Walk Score of 21 and has 117,517 residents.