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Cohabitation [InProgress Version 0.51] (2017) PC
This is a game I've been tinkering with on and off for the past few months. It's a raising / corruption sim with 3D images made using Illusion's HoneySelect. You play as Calvin who now lives with his niece Megan, and the goal is to corrupt her. It's a fairly modest game. While it's technically an RPG Maker MV game it plays nothing like a regular RPG as it is pretty much purely menu based with a point-and-click system.
Web [InProgress Version 0.1.5] (2017) PC
The game about a young girl who came with her husband in a small town. My husband got the chance to take a good position, but before that he must undergo training and this will depend on what awaits them - a beautiful rich life, or they will come back to where started. They are hoping for the best but do not even know that already hit the web and how they had not fluttered - more confused.
Lily of The Valley [Version 0.7 Beta] (2017) PC
You will be playing the role of "Lily" and making decisions about the course her life will take.
World of Porncraft - Whorelords of Draenor [InProgress - Ver 2.3 VIP] (2017) PC
World of Porncraft: The Whorelords of Draenor – is an innovational stealth RPG/NSFW parody. Actions take place in the alternative reality that differs from the original expansion plot.
The main heroine - Sylvanas Whorerunner prepare to fight the Real Evil! Orcish clan "Iron Dicks" invade our world from the remote past in order to conquer the whole Azeroth, to force all the races on their knees and turn their females into slaves.
The orcs of the "Iron Dicks" clan caught Sylvanas and throw her into a prison full of breed-hungry monsters. Will The Banshee Queen be able to escape from the dungeon keeping her pride intact or the most hideous beasts of Azeroth will use her as a cheap whore? All depends on you!
Daryce [Inprogress Version 1.d - End01] (2017) PC
This story revolves around Daryce during the time when she was informed that her parents had decided to divorce. She came to your place one late night, like many other nights, Seeking some companionship. This marks the start of your story with her. There will be choices determining how you end up with her in the story, with a similar relationship system from Ethan's Legacy. Releases will be episodic, updated weekly along with the releases from Ethan's Legacy.
Research into Corruption [v0.5.0b] (2017) PC
- Corruption System
- Randomisation System (Still to be fully implemented)
- Enhanced experience through cut scenes.
- Get to know the Charaters through Cut scenes (Still to be fully implemented)
- Progression System.
- There will be several ways of getting events in the game.
- Objects to interact with that lead to different events...
Two Sides [InProgress Version 0.035] (2017) PC
Two Sides is an Adult Game based on a story about a young man who decides to try his luck in a big city. The problem is that in one of his jobs to get money to keep up, he ends up acquiring the ability (or curse) to change his gender, voluntarily or randomly according to his level of masculine or feminine excitement.
The difference of this game is that it focuses on the principles of each player. During the game, the player can decide on the actions of the main character, putting his or her principles, goals and tastes into their decisions, conquering older or younger girls, attempting an Incuous romance, heterosexual, gay or both, and many other things.
Sea Holiday [InProgress Version 0.5 ME] (2017) PC
It is a sequel of Road Trip. This time Jennifer will go on holiday trip with her boy friend and family members. But her boyfriend and her cousin will do something stupid, which will spoil their vocation and Jennifer will have to deal with new problems again.
Many feedback are taken into account from Road Trip. This game will focus far more strongly on the story and the plot of the game. It will be new elements and Jennifer will have multiple appearances.
Lovely Guests [InProgress Version 0.70] (2017) PC
You'll assume the role of a young guy who lives with mother in a big house. Now some guests are going to stay at your house for a while. You will see how this visit will affect the life of the protagonist. At this moment the game has two different endings.
The Carnaloreon [ Chapter 1,2 – Version 0.22 ] (2017) PC
Sweet and sexy, teenager Lucy Brightwater is having a rather dull summer vacation before college resumes. That is until an unexpected letter arrives for Lucy, and her big sister Nicky.
The letter, and their response, sets off a chain of events that turns dull into delicious and puts sizzle into summer. Mixing travel, fantasy and lots of vigorous and happy sex, The Carnalorean will tell us all about the "adventures" of Lucy and Nicky, and includes a variety of interesting and willing partners.


text: Arggghhh. Went to a family reunion in Chino Hills, CA. Took lots of pictures and at the end of the day when we were cleaning up, my camera bag was stolen... Lost my D70S, Sigma 17-70, 85 1.8, 28-200G, SB600 and 4 cf cards... Now that I am starting over, what would you recommend? D200 (new), D2Hs (used for $1750) or going to the other side Canon 30D? I don't really print larger than 8x12. I sometimes shoot in low light and shoot some sports (cycling, kids baseball and volleyball). I'm really considering the D2Hs but I sometimes crop and the 4MP has me a bit worried. I crop (not too heavily) because I'm still learning how to compose the shots. With the D200, there would be a warranty and the Canon... I don't know too much about it. Oh, I'm selling my ATV in order to get more camera gear. It's been sitting in my garage for 8 months without being ridden. I figure I could get some money for it and use it on something that I'm enjoying right now.

subset: commoncrawl


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Browse these roofing contractors with great ratings from Thumbtack customers in Campbell.
Jon Cunningham did my house as well as my neighbors house in Hayward and did a excellent job. He's very knowledgeable in his field of expertise and honestly point out problems that needs attention to prevent problems in the future. His timing and scheduling was awesome. Definitely I would refer him to whoever need roofing work. Keep up the good work Jon!! B. Lee
I was in urgent need for a handyman, as a large part of a wall, insulation & floor in my storage closet was damaged by my leaking water heater. I decided to try Thumbtack and was very happy to see that Arisel from AA Cardenas reached out to me and said he can start work immediately. He was very prompt in replying, and very easy to reach on phone & text before, during and after the work was completed. When he came, he assessed the work to be done, gave me a very clear outline of materials needed and the labor cost. He told me he could finish the work in 2 days, which is exactly what my deadline was, and he did finish all the work in 2 days flat! He offered to go and pick up all the material from the hardware store, and worked till late on the first day to make sure he got as much work done as possible. He was very professional in putting up new insulation, patch sheet rock, applying texture to blend with existing wall texture and paint the area. He always cleaned up before he left and was very open to me asking questions about various things he was working on. Arisel was very nice to talk to as well, and he was accommodating to all my questions. He even came back 4 days later, at my request, to put floor molding. Overall, I'm extremely satisfied with the work Arisel did, and would definitely hire him again.
Dynamic, good communication and teamwork between contractor and customer. Benny offered several ideas which gave the project added value, saved time and some dollars.
Daniel is professional and punctual. He did a super job from roof inspection to preparing list of materials and then completing the job in time. He worked long hours to complete the roof work as heavy rain was forecast the following day. I recommend Daniel for all types of roofing jobs.
Could not have been happier with Israel & Artistry Roofing. They were prompt, professional, good value and fixed the problem and did it right. Not only did they set an appointment ASAP- but he was right on time and was cautious to take his shoes off and respect the home interior. He also allowed me to come up on the roof with him (I really wanted to see the problem) and explained the problem/solution in a straightforward way I understood. The fix was done with experience and obviously by someone who cares about the quality of work.... it was really refreshing to work with a company with integrity.
I would recommend Mendez Personal roofing to everyone for the following reasons: quick response back, speedy next day service, they take pics and advise you if something needs to be replaced & afterwards send a pic back with the new replacement part affixed, price is real good and the service was excellent. My gutters are clean and my leak into my home from the harsh storms is no longer there. I'm also a Realtor and very picky of whom I use. I will reccommend all my future clients/frnds/family to use Mendez Personal Roofing! I'm a very satisfied customer.
everything you would want in a roofer,I got in Bryans Roofing.They were great and even their clean up crew was done well.
Gerardo did a great job installing, priming and painting a downspout at our home. He is very pleasant to deal with and takes a lot of pride in his work. I would definitely hire him again!
Adam was easy to work with, very professional and completed the job as stated. Would recommend him for all your roofing needs.
I was really happy with the results of this roofing project. Carlos, the project manager and supervising roofer, came to my house to assess the work and give me an estimate quickly. He was prompt, professional, and very knowledgable. He was able to quickly assess the issue and suggest a remedy. Within 48 hours, he supplied estimate with 3 separate options for the project. He was easy to reach when I had questions and once I accepted the bid, the work was scheduled quickly. On the work day, he and his crew showed up right on time and work was completed on time and as promised. Carlos is a nice guy, straightforward and professional all the way. Would definitely hire again.
Replacing a roof is major project with serious expenses. I recommend anyone considering a similar project to seek out G.T. Roofing. From start to finish G.T. Roofing met and exceeded my expectations. I met with G.T. Roofing just two times to inspect the job site and discuss the details of the work. A few email exchanges later, a written contract was delivered and the project was a go. The whole process was painless. Once the job was scheduled a crew came early on a Saturday morning, tore out the old roof, cut out new attic vents and laid down a new roof system. The new gutters tied the entire roof system to the house and looks like decorative molding. Since the installation in mid -October, my new roof system has already been tested by rain, wind and record temperatures. It performed so much better than my old roof. My roof design is aesthetically perfect and the circulation and moisture inside the house has greatly improved. When the crew first arrived I knew they would be prepared and organized. G.T. Roofing has the knowledge, the means, and the skills to design and complete a project to my specifications. I don't doubt they can handle even larger residential and commercial projects with the same professional level of execution. If you care about your home, you want a contractor who cares just as much. I am thrilled with the work by G.T. Roofing!
We hired Eli for a total interior renovation of our newly purchased home, including changing the layout of our first floor, adding a half bath, 2 full bath and 1 kitchen reno, hardwood floor, HVAC, roofing, repiping & electrical work. Total value of the project exceeded 140K, and lasted ~ 4 months. Eli & team delivered good quality work and kept us at our budget. He is a professional with high integrity. He was always responsive, provided helpful, thoughtful and truthful advice, and committed to his promises. Our journey together wasn't without hiccups, but Eli is someone you can trust as a partner battling any challenges together along the way.
They showed up and did the work quickly and expertly. I'm planning on hiring them again for the rest of our roofing job.
Great job done on roof repairs!
Jon got in touch with me within an hour of my posting the job (trimming two trees), and came out to provide a quote the next day. After giving a thorough assessment of the trees, he also noted some related problems (dirty gutters from the overhanging trees), and discovered a broken roof tile, which had provided rats access to our attic (another problem we are currently dealing with), he provided a very reasonable quote and offered to do the job the same day. He spent all afternoon at the house, completed the job as described, kept in regular contact with me as the work progressed (I was at work at the time) and cleaned up thoroughly when finished. He also provided pictures to document the before/after, which I appreciated, as I could in turn provide them to my landlord. I am extremely happy with Jon's professional and courteous service and will certainly look to him for any future jobs. I highly recommend you consider him for any project.


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Appalachia Reporting Project
In mid-2017, Rewire.News launched a project to develop and publish original on-the-ground reporting in Appalachia. Focused on the structural and political challenges that undermine health, justice, and economic well-being, our Appalachia coverage centers on the Central Appalachian region (including Kentucky, North Carolina, Ohio, Tennessee, Virginia, and West Virginia), and prioritizes work by writers living and working in these communities.
Designated by the Centers for Disease Control and Prevention as a medically underserved region, Appalachia lacks primary health care providers and other forms of care, due in part to a dearth of economic opportunity and investment, resulting low incomes, geographic isolation, and low rates of educational attainment. But Appalachia is also a vast and diverse region that has been under increased scrutiny since the 2016 presidential election. Rewire is committed to telling its many stories.
Appalachia's Suicide Rates Are Startlingly High. For Veterans, They're Even Higher.
'A Growing Movement': Coalitions Are Expanding Legal Services for Appalachian Victims of Domestic Violence
Long Waits and Limited Providers: Mental Health Care While on Medicaid in Appalachia
Federal Appeals Court Dismisses Challenge to Wisconsin's 'Personhood' Law
A panel of federal judges on Monday dismissed a case challenging a Wisconsin law that allows for the involuntarily detention and treatment of pregnant people, while the fetus gets legal representation.


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Brighton, Milton Keynes, Cambridge, Luton
OTE Salary band: £60k - £70k
Sales Manager, Account Director - Training and Development, NHS & Public Sector. Home Based £65,000 OTE £90,000 uncapped + Exceptional benefits package. This is an outstanding client relationship management sales opportunity working for a specialist provider of e-Learning, Training, Software and Workforce development solutions to both private and public sectors. Core sectors would include ...
Other Sales Director Jobs in Cambridge
Milton Keynes, Bedford, St Albans, Stevenage
OTE Salary band: £60k - £70k
Sales Manager, Capital Equipment, Field Based from Office in Bedfordshire. Up to £70,000 Basic, £120k OTE + Car or Car Allowance + Excellent Benefits Package. The role is ideal for a dynamic and driven sales focused leader looking for a career move. To apply, you will be a strong character with superb coaching and mentoring skills, and will probably be MBA qualified, with the commercial nous to...
Other Sales Director Jobs in Bedford
Aylesbury, Buckingham, High Wycombe, Milton Keynes
OTE Salary band: £80k - £90k
Field Sales Manager – Direct Sales
Basic Salary: £40,000 plus £625 monthly net pay, uncapped OTE, realistic earnings £80k plus
Purpose To manage a team of 8 field sales executives promoting and selling funeral plan sales in line with company targets and procedures
Do you want to join a fast paced Company in a rapidly growing industry? Are you ambitious, driv...
Other Direct Sales Jobs in Aylesbury


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UST Global invests in digital healthcare start-up MyDoc
MyDoc plans to use the investment to fund its ongoing initiative to drive population-wide digital health programmes, which includes disease management and health data tracking
Mumbai: US-based digital technology company UST Global on Wednesday said it has invested an undisclosed amount in MyDoc Pte Ltd, a Singapore-based digital healthcare services discovery platform with a focus on Asian and European markets.
MyDoc was founded in 2012 as a doctor consultation and efficiency enabler start-up by Snehal Patel and Vas Metupalle. It currently offers services in Singapore, Malaysia, Hong Kong and Sri Lanka.
MyDoc provides services through its MyDoc mobile application and web services. The digital platform allows users to select, compare and book appointments with specialists, diagnostic centres and hospitals. Users can also order medicines and access their health insurance portfolio.
MyDoc plans to use the funds to expand its digital offerings. The investment will fund MyDoc's ongoing initiative to drive population-wide digital health programmes, which includes disease management and health data tracking.
MyDoc had earlier raised an undisclosed amount in funding from August Capital Partners, a venture capital fund based in Singapore, VCCircle reported in 2014.
"In healthtech, access to critical ecosystem partners plays a crucial role in successful roll outs. UST Global's technology capabilities as well as their global customer relationships will be extremely beneficial for MyDoc in our next phase of development and growth," said Snehal Patel, chief executive and co-founder at MyDoc.
UST Global is a digital technology company that provides advanced computing and digital services to large private and public enterprises around the world. UST Global is headquartered in Aliso Viejo, California and operates in around 21 countries.
"MyDoc will complement our suite of digital offerings and we strongly believe that this investment and partnership with MyDoc will create significant value for our customers in their digital transformation journey," said Krishna Sudheendra, chief financial officer at UST Global.
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- LIC seeks govt nod to buy controlling stake in IDBI Bank


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From breaking news to debate and conversation, we bring you the news as it happens
Law firm donates for Coeliac Awareness Week
20 Jun, 2018 11:30am
4 minutes to read
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$38.5 billion super fund + Government's assets ($22.2 billion net debt) = $16.3b surplus.
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When you finally discover your legs after 37 years, it's not a great sign
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The Smear Your Mea campaign founder has been farewelled by many.
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A man will appear in the Rotorua District Court on July 2 after a gang fight on Monday.
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Whanganui's unbeatable sailor and genius IT man Barry Humbug died last month.
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The approach followed a 200-rider rally on Saturday protesting the council's decision.
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A driver has hit a power pole near EIT in Taradale.
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If a European citizen visits your website, you need to be in line with GDPR requirements.
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The Western Heights High School student will attend the Asian Science Camp in Indonesia.
- 3 minutes to read
Rivercity Tree Services is celebrating 10 years in business.
North Island News
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Rural News
Mexico is looking at exporting avocados to NZ and Australia.
The levy money is spent on grower representation, advocacy and communication with growers.
Synlait Milk will develop its second nutritional powder manufacturing factory.
New rates expected to be instrumental in attracting more people into the industry.
Rivercity Tree Services is celebrating 10 years in business.
The investment gives Comvita a 20 per cent stake in the company.
The payout followed a probe by a Labour Inspectorate.
"On this journey it really is a roller coaster..."


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The dialogue is fantastic, with Eastwood utterly believable in his testifying to the evils of whisky, and Hackman totally at ease with saying he "et it." Richard Harris's English Bob is an unforgettable pansy of a villain, and the widescreen cinematography is lush during the day, ominous during the invariably rainy nights.
Continue reading: Unforgiven Review
Continue reading: The Guilty Review
Continue reading: Rock My World Review
Continue reading: Tail Lights Fade Review
It was on this day (June 15th) in 1979 that Joy Division unveiled their iconic debut album 'Unknown Pleasures'.
The best Stephen King adaptations in film history.
Download Festival finally got the stunning weather it deserved, as over 100,000 fans descended with the likes of Guns N Roses, Ozzy Osbourne and...
Slaves sweat it out in the video for their latest single 'Cut And Run'; the first single from their forthcoming new release, the details of which are...
A look at the line-up for the festival's 50th anniversary.
This year's winning shows were 'The Cursed Child' and 'The Band's Visit'.
They perform the song together for the fourth time ever.
They'll release 'Joy as an Act of Resistance' in August.


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Australia: The Australian family law system review: What you need to know
Last Updated: 14 June 2018Article by Danielle C Hadida
What are the changes?
In May 2018 the Attorney General Christian Porter announced
changes to the Family Court of Australia and Federal Circuit Court.
These changes are scheduled to occur in early 2019 and would see
the two systems combined into one in an attempt to reduce the
lengthy wait times for Register for Access and our Free Biweekly Alert for This service is completely free. Access 250,000 archived articles from 100+ countries and get a personalised email twice a week covering developments (and yes, our lawyers like to think you've read our Disclaimer).
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Foreign or concurrent wills are proven and validated simultaneously in accordance with laws of the different countries.
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The government proposes a major overhaul of the administrative and structural aspects of the federal Family Court system.
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Delaware: Rail opens for 'Locket'
After being boxed in and blocked from the backstretch to deep stretch, heavily favored Love Locket ($4) found room along the rail and drove clear to a one-length victory in the $58,500 Irish Sonnet Stakes for 2-year-old fillies at Delaware Park.
Trained by Todd Pletcher and ridden by Ramon Dominguez, Love Locket is now 2 for 2 since being stretched out to two turns for her second career start. She covered the mile on a fast track in 1:41.69.
Love Locket was pinned on the inside until the stretch, then found a wall of horses in her path when Dominguez tried to take her off the rail. Forced to go back inside, Love Locket responded when a hole finally opened.
Gorgeous Mistress came from next-to-last in a field of six to take second, finishing three-quarters of a length in front of Missy's Advantage.


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Idaho Springs, CO Wild Game Processing
YP - The Real Yellow PagesSM - helps you find the right local businesses to meet your specific needs. Search results are sorted by a combination of factors to give you a set of choices in response to your search criteria. These factors are similar to those you might use to determine which business to select from a local Yellow Pages directory, including proximity to where you are searching, expertise in the specific services or products you need, and comprehensive business information to help evaluate a business's suitability for you. "Preferred" listings, or those with featured website buttons, indicate YP advertisers who directly provide information about their businesses to help consumers make more informed buying decisions. YP advertisers receive higher placement in the default ordering of search results and may appear in sponsored listings on the top, side, or bottom of the search results page.
1. Western Daughters Butcher Shoppe
3326 Tejon StDenver, CO 80211
2. Wheat Ridge Poultry and Meats
The best place for fat rendering and pork fat. Not to mention some of the nicest people around. Thier fresh eggs are top notch. I have been going…
3. Meat Cleaver
I have taken my deer and elk to the meat cleaver and they always do a good job! geat jerky and brats all at a fair price.
4. Tymkovich Meats
We have been going here for years. Excellent product & service. Hope to be going there for many more years to come.
5. Arapahoe Meat Company
We used them for my daughter's graduation party in Boulder. The service could not have been better and neither could the food. They were very prom…
6. Steve's Meat Market
I went to Steves last year for the first time and will return this year. The customer service was oustanding, the prices were reasonable, and the Je…
7. Bee Bee Que Inc
7033 E 49th AveCommerce City, CO 80022
8. Il Mondo Vecchio
1174 S Cherokee StDenver, CO 80223
9. MDs
4709 Washington StDenver, CO 80216
10. Great West
8950 Barrons Blvd Ste 102Highlands Ranch, CO 80129
11. Us World Foods Ltd
11150 Huron St Ste 207Northglenn, CO 80234
12. Custom Made Meals
2351 E 70th AveDenver, CO 80229
13. Custom Corned Beef Inc
5575 Logan StDenver, CO 80216
14. Huong Duyen Products
6885 W Colfax AveLakewood, CO 80214
15. Polidori Meat Processors
3327 Tejon StDenver, CO 80211
16. Colorado Natural
4120 Brighton Blvd Ste B-5Denver, CO 80216
17. Temptee Brand Steak Inc
2011 E 58th AveDenver, CO 80216
18. Boulder Natural Meats
5340 Franklin StDenver, CO 80216
19. Rocky Mountain Meats
I have been using Rocky Mountain for 8 years, and it has not been the same since the parents retired. The service has been terrible, the attitude of…
20. Rocky Mountain Natural Meats
Rocky Mountain Natural Meats LLC has the BEST ground bison/buffalo in the world! Since beef makes me sick to my stomach, I have started eating buffa…
21. Double BRB Cattle Compamy
CR 13Parker, CO 80138
From Business: Our beef are raised 100% natural 100% growth hormone steroid and implant FREE!!!! Please take a minute and check out our website and also please feel free to call…
22. Royal Meat Co
The worst service ever, bad customer service, I went today to buy a lamp for the holidays, I talked to the owner in the phone yesterday, he gave me …
23. Carniseria Dariana
12028 E Mississippi Ave Unit F1Aurora, CO 80012
24. Mi Preferida Meat Market
274 E Bridge StBrighton, CO 80601
25. Carmine Lonardos
This is a great local market, and I highly recommend supporting the local businesses. This market is quaint, the staff is very knowledgeable, person…
26. Sawa Meat & Sausage
3206 Wadsworth BlvdWheat Ridge, CO 80033
27. Carniceria Del Norte
2401 E 88th AveThornton, CO 80229
28. Jin Chan
2835 28th StBoulder, CO 80301
29. Wally's Quality Meats
Wally's is really a great meat shop, and although the prices can seem high, the quality of their products is outstanding, their selection is fantast…
30. Good Eatin' Premium Meats
5150 E 39th AveDenver, CO 80207


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|Adam Hicks
|Felicity Price
|Camille Guaty
|Mackenzie Aladjem
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|Kellee Stewart
|Tony Way
|Wendy Clarice Jordan
|Ilse Salas
|John Lloyd Young
|Marsha Warfield
|Beth Broderick
|Valerie Cruz
|Ann Harding
|Seth Smith
|Karan Kapoor
|Elize du Toit
|William Wyler
|Khamani Griffin
|Mykelti Williamson
|Gayle King
|Laura Birn
|Satyajeet Puri
|Jonathan Banks
|Karyn Halpin
|Nicholas Lyndhurst
|Melissa Newman
|Shannon Leroux
|Joey Graceffa
|Ariana Richards
|Daphne Zuniga
|Nadine Velazquez
|Om Puri
|Eva Gabor
|Bob Marley
|Raymond Burr
|Bethenny Frankel
|Maurice Evans
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There either is or is not, that's the way things are. The colour of the day. The way it felt to be a child. The saltwater on your sunburnt legs. Sometimes the water is yellow, sometimes it's red. But what colour it may be in memory, depends on the day. I'm not going to tell you the story the way it happened. I'm going to tell it the way I remember it.
The Lizzie Bennet Diaries is an innovative, original episodic video and social media series produced for the web. Adapting Pride and Prejudice to the modern era, Lizzie Bennet tells the classic Jane Austen tale from the point of view of an Elizabeth "Lizzie" Bennet who grew up in a world of cell phones, video cameras, and social media. The series was created by popular YouTube personality Hank Green and Streamy Award winning web video writer Bernie Su.
The holiday season is bringing more than cheer for actress Jessica Capshaw. The Grey's Anatomy star announced on Monday that she and her husband, Honest Company co-founder Christopher Gavigan, are expecting their fourth child. "The holidays have certainly arrived … All of our lives are being added to by the lights, the music and cheer!!" she captioned a photo of her family at a Christmas tree farm on Instagram. "This year our family has reason to further broaden our smile … baby number four is on the way!! I am a lucky, lucky girl…"
The quickest way to tell whether an actor is serious about his or her career is to look at their "headshot".Is it a professional photo? Or is it a snapshot taken on prom night? If you're using a snapshot, it's like showing up to race the Indy 500 in a VW Beetle. Nobody is going to take you seriously. I'm sorry, people… you can send me as much angry e-mail as you want about this, but it's true! Don't tell me you're destined to be a major Hollywood star but you cannot scrape together the cash to get professional headshots.
The Grinch from Dr. Seuss' How the Grinch Stole Christmas! The Musical stole the spotlight at the Empire State Building's 86th Floor Observatory December 14, 2012, to promote the musical's limited holiday engagement. Discover the magic of Dr. Seuss' classic holiday tale as it comes to life on stage. Featuring the hit songs "You're A Mean One, Mr. Grinch" and "Welcome Christmas," The Grinch discovers there's more to Christmas then he bargained for in this heart-warming holiday classic.
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Card making, rubber stamping techniques and project videos for papercrafters
I have a question- I am looking to use my laser printer to print a name and foil-but I also want to stamp on my card- Do I laser and foil first ?? Then ink and heat emboss??
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- UK Sales 01737 783 101
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Constructor Tig Welding Accessories
Found 5 product(s). Showing product(s) 1 to 5.
Back Cap - WTT41V24 - Long, WP9,20No stock@62946£6.04 (ex VAT)£7.25 (inc VAT)
These back caps screw onto the back of TIG torches and control the length of tungsten welding electrode.Code: PR-WTTBC... read on
Collet Body - WTT10N31 - 1.6mm, WP17, 18, 26No stock@62948£5.86 (ex VAT)£7.03 (inc VAT)
These collet bodies fit the WP series of Tig torches, and holds external threads for the ceramic and the back cap.Code: PR-WTTCOB... read on
TIG Torch Microswitch & Cable - WTT950-8 - 8mNo stock@62949£15.40 (ex VAT)£18.48 (inc VAT)
Tough weldcraft type tig welding torches fitted with Lincoln fittings to connect straight onto Lincoln Invertec Tig WeldersCode: PR-WTTMC... read on
Tig Ceramic - WTT10N45 - 16mm Bore, WP17,18,26 (No 10)No stock@62950£5.47 (ex VAT)£6.56 (inc VAT)
These ceramics fits the WP series of TIG Torches and control the shielding gas to the weld pool.Code: PR-WTTTC... read on
TIG Torch Package - WTTRWP18-25FX-SSW - WP18, 25 FeetNo stock@62951£162.63 (ex VAT)£195.16 (inc VAT)
Tough weldcraft type tig welding torches with standard 3/8 inch BSP male machine connectionsCode: PR-WTTTP... read on
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Great mower , good on rough ground. Delivered on time...
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MPHE Stands For : Masters in Population Health Evidence | Micro Plate Heat Exchanger | Micro Plate Heat Exchangers | Minnesota Palomino Horse Exhibitors
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Question about 1996 Jeep Grand Cherokee
Posted by sdessesaure on
SOURCE: I have freestanding Series 8 dishwasher. Lately during the filling cycle water hammer is occurring. How can this be resolved
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Tips for a great answer:
Dec 15, 2013 | 2001 Cadillac Eldorado
Apr 17, 2013 | 2003 Toyota Highlander
Feb 16, 2013 | 2002 Chevrolet Tracker
Aug 31, 2012 | Cars & Trucks
Engage the emergency parking brake, to avoid causing the car to roll or
move when removing the bumper.
the screws holding the wheel well liners in place with a screwdriver. This will
expose the screws holding the bumper bolts. • Release
the bolts holding the bumper in place, using a wrench, and have a friend
support it while it remains wired to the car.
Disconnect the wiring running to the bumper to separate the fog lights
from the car. Pull out the light fixtures from the bumper cover.
Remove the grill in the bumper cover, taking out the screws holding it
into the cover. This will allow you to separate the grill and the bumper cover.
Secure the grill and light fixtures into the new bumper cover, using the
hardware you removed from the old cover.
Reconnect the necessary wiring. Support the bumper cover in front of
your car or have your friend hold it in place again.
Secure the bumper cover using the retaining bolts you took out earlier.
Tighten the bolts to hold the bumper cover securely against the car.
Replace the wheel well liners with the screws you took out.
Jul 07, 2012 | 2006 Chrysler Pacifica
Sep 06, 2011 | 2007 Toyota Camry
Jan 02, 2010 | 1999 Lexus RX 300
May 20, 2009 | 1997 Ford Explorer AWD
May 03, 2009 | Chevrolet Impala Cars & Trucks
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Jeff J. is drinking a King George by Monnik Beer Co. at Whiskey Dry
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26 May 2017, 08:13 | Kristine Mills
Maybe the league's best center. It's notable that Boston is without All-Star Isaiah Thomas, but the Celtics have given the Cavaliers a run for their money over the last couple of games.
They were two of the NBA's best players during the regular season and played pivotal roles in helping their respective teams reach the Eastern Conference finals. The Warriors have managed it-so much so that Lue already seemed to be sweating some of the Cavs' habits when it came time for his sideline interview. No matter which path they choose, however, one question looms over all of them: What should they do with Thomas? The Celtics, who shot just 44.3 percent from the field, couldn't capitalize on James' absence and took a mere 57-47 halftime bubble.
"He just never had the opportunity because of the team at that point in time". In the normal course of life, a player grieving at the loss of a family member would have excused himself from any kind of professional proceedings. The Celtics also managed to overcome a 0-2 deficit to the Bulls and outlasted Washington in a seven-game series, although he had Thomas for those games. Still, Boston covered the spread for the second straight game.
This, however, is where the story gets complicated. Presumably, it's the player who was given a four-year max contract last summer and who makes $14.5 million more than the roster's next highest-paid player. Still, Cleveland can finish things off tonight and I think they will play well on the road. "They're paying everybody else". I'm pretty sure Steph Curry couldn't even do this. This season was his seventh year in the National Basketball Association. That's especially true when one considers a max contract next summer will begin with an annual salary of more than the total amount he'll have made in his career.
"We played as well as we'd played in the entire playoffs in the first half and then for various reasons that didn't happen in the second half". Bradley's game-winning three-pointer with 1/10 of a second left on the clock in Game 3 kept the series alive for another game in Boston. That puts him just one behind Bill Russell, whose Celtics teams played in eight consecutive finals from 1959-1966.
Trump taking unique Saudi-to-Israel flight
He could be seen entering the holy site along with First Lady Melania Trump under heavy security. We can not stand a moment longer for the slaughter of innocent people", Trump said .
Comey Agrees To Testify Before The Senate Intelligence Committee
Mr Rosenstein said, although he was personally fond of Mr Comey, "I thought it was appropriate to seek a new leader". Maryland Congressman Elijah Cummings called Trump's reported comment "astonishing and extremely troubling".
Divings bans to be introduced to English football
Should "deception" have been proven to have taken place, the player who received a yellow or red card will have that rescinded. Then Hull winger Robert Snodgrass apologised for diving in a Premier League match against Crystal Palace earlier this season.
In fact, they completely silenced him midway through the second quarter, as James picked up not one, not two, not three, but four personal fouls with over six minutes remaining in the second quarter.
All of this creates the backdrop for what should be a fascinating next few months in Boston.
James spoke Thursday during the morning shootaround before the Cavaliers play the Boston Celtics in Game 5 of the Eastern Conference finals.
But Thomas turned up to play for the Celtics against the Chicago Bulls in the first-round despite the vast personal trauma he was undergoing.
Boston looks forward to the NBA Draft on June 22, when the Celtics have the first overall pick.
Texas' New 'Transgender Bathroom Bill' Keeps Biological Sexes Separate in School Facilities
Greg Abbott , R, has in the past expressed support for bathroom restrictions and is expected to sign a measure if it reaches desk. But the NFL, NBA, leading business lobbies and Hollywood celebrities have urged Texas to avoid the issue.
Duterte declares martial law in southern Philippines
Duterte, a native of Mindanao, cancelled a meeting set for Wednesday with Russian Prime Minister Dmitry Medvedev. Two soldiers and a police officer have been killed, Defense Secretary Delfin Lorenzana said.
Iranian president calls US relations 'a curvy road'
Israel was his second stop on a nine-day tour aimed to test the waters for reviving the dormant Israeli-Palestinian peace process. We believe you're willing. "Hundreds of millions of dollars in weapons deals is something we should receive explanations about".
Firing 'nut job' James Comey took off pressure, says Donald Trump
White House hopes that Mr Trump could leave scandalous allegations at home were crushed in a one-two punch of revelations that landed shortly after his departure.
The 'No Fun League,' Relaxes End Zone Celebration Rules
Apparently they are trying to shake the No Fun League nickname and today they announced that touchdown celebrations are back. Goodell's email also mentioned how the league is placing an emphasis on speeding up the pace of games.
Hopewell mom says got second-degree burns after using sunscreen
Still squeezing the last gloopy drops out of last year's sunscreen bottle? Does it give you protection? Yes. The risk of melanoma and other skin cancers increases with each tan, especially tanning booths.
WWE RAW from Grand Rapids, May 22
More importantly, how will R-Truth respond? Extreme Rules , a WWE Raw branded pay-per-view, will take place on June 4th. WWE has announced that Neville will defend the title against Aries in a submission match at " Extreme Rules 2017".
LEADING OFF: Adams set to join Braves, Yankees-Rays reset
Freeman was leading the majors in slugging percentage when he was hurt, hitting.341 with 14 home runs. He is batting.275 with 13 doubles, one home run and 15 RBI in 35 games for Single-A Rome this season.
Lukaku, Sanchez hunt Kane in late Golden Boot showdown
Leicester's joy was short-lived when Spurs restored their two-goal advantage two minutes later through Kane's close range header. Tottenham: Lloris 6, Dier 7, Alderweireld 8, Vertonghen 7, Davies 7, Wanyama 7, Dembele 7, Sissoko 6, Alli 8, Son 9, Kane 10.
In a separate statement , the prosecutor noted that in Sweden a criminal investigation has to be conducted as quickly as possible. Long added: "This has gone on long enough". "We have today won an important victory , but the road is far from over".


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Cecilia Velazquez Futon, 2018-02-20 17:33:33. A good quality finger jointed cross rail might be just as strong as a solid cross rail in many ways, it still accepts a downward pressure that can force poor quality joints to loosen. Experience shows that a solid continuous hardware cross rail is less likely to break than a segmented one. If the futon you are considering buying has segmented stretcher rails, ask the dealer to explain the history of that manufacturer's products with this system. Ask if a cross rail does fail, what the dealer's policy is about replacement. Although, most dealers generally will not pay for shipping, they should at least offer the replacement part for free with in the span of the warranty.
Etta Mayo Futon, 2018-04-18 01:33:51. The design of the futon cover is also important. The cover should have a zipper three-quarters of the way around. This ensures that you can get the cover on and off easily. Many covers skimp on the zipper opening in order to keep the price down. It is worth an extra $50 to get a better design. After the first time you struggle to put on the cover, you will wish that you had coughed up the extra cash.
semangat Futon, 2018-03-14 00:04:43. Another early futon design patent was filed in 1985 (Patent Number 4642823) assigned to Robert Fireman's Furniture Gallery, Inc. invented by William B. Wiggins. What was interesting about this early take on futon design was the incorporation of arms on the sides of the futon which allowed the seat and back sections to integrate into the arms and allow for operation without having to rearrange the futon. This early design featured two pivoting swing pieces attached from the back rails into the back section. The seat and back sections were connected together using steel pins. What I found most interesting about this design is that it effectively converted the futon from sofa to bed from the front. Once in the bed position additional legs were extended down for support. Additionally a dowel and rod interlocked with the seat and back section to safely lock the two in a horizontal position. This design would be considered a bi-fold by today's standards which means that 2 sections are used to create the seating and sleeping portions of the frame itself.
Etta Mayo Futon, 2018-04-18 01:33:51. You can get a great futon cover for under $200. That is a fraction of what you would spend on a new sofa. So indulge and really shop for the cover that you love. Maybe it will be a microfiber cover or black leather. Whatever the fabric, whatever the design, you can enjoy knowing that you spruced up your living room without spending a bundle of money.
Peggy Santos Futon, 2018-04-15 17:49:06. You can match the futon to existing furniture, or you can select the futon first and build the other furniture and dcor around it. Futons make excellent editions to the media room or entertainment room. They also work well in guest rooms, because it will allow you to use the room as a sitting area, reading area or television room when it is not being used. Futons are also great for kids rooms because they can enjoy games, television or visiting with friends without having an extra piece of furniture.
Peggy Santos Futon, 2018-04-16 15:09:16. Still, it is important to remember that futons are not only dual purpose pieces of furniture,-- they are also mechanisms that require added reinforcement. For this reason, the smarter manufacturers have reinforced their futon frames with various metal brackets and support beams called stress supports to make their futons even more durable. These companies to brag about the beneficial features of their futon frames which makes they consumer's quest easier. These companies supply product specifications list which is a good place to start your research about a particular futon frame you are interested in buying.
Lynnette Rutledge Futon, 2018-04-16 17:24:32. One of the best improvements you will notice that you now have in the latest futon styles and designs that you can now choose from is the craftsmanship. Even if you have previously bought a futon in the past during your college days, you are sure to be pleasantly surprised by the excellent breakthroughs in the craftsmanship that is applied to these new designs. While you can still find some very simple and basic designs that feature the traditional box shaped frames, which definitely provide excellent options for those of you on a more restricted budget, there are now many other designs available that feature some very intricate and detailed designs.
semangat Futon, 2018-04-19 04:44:57. First, let's talk about fabric. Do you want cotton? Or leather? Or even denim? Maybe you want a futon sofa that looks like a regular sofa. They make covers in upholstery fabric, too. What fabric you choose depends on your own personal style and the needs of your family. If you have a big family, you should save yourself the grief and get a heavy duty futon cover. A simple denim will be inexpensive and wear like a good pair of jeans. If that is too dark, you might want to shop for a upholstery fabric. It is designed to stand up to the wear and tear of daily use.
Georgia Henderson Futon, 2018-04-16 06:50:21. You can match the futon to existing furniture, or you can select the futon first and build the other furniture and dcor around it. Futons make excellent editions to the media room or entertainment room. They also work well in guest rooms, because it will allow you to use the room as a sitting area, reading area or television room when it is not being used. Futons are also great for kids rooms because they can enjoy games, television or visiting with friends without having an extra piece of furniture.
Anna Burris Futon, 2018-04-21 11:25:38. So you've just moved into your new house or apartment and you're looking to fit it out with furniture. However, what do you do if your apartment's too small for a decent sized bed? Bedding can take up a lot of essential space and it can be a really big problem if you're living in a one-room flat. This is where futons will come in really useful.
semangat Futon, 2018-04-19 02:09:25. Our store stopped carrying black metal frames a few years ago for many of the reasons listed above. We decided to shift away from low end products and concentrate on proven well made, quality higher end products. So many people walk through our furniture store and when offered a futon frame as a possible piece of furniture for their home are told by the customer, \"I bought one of those years ago at [insert mass merchant name here] and it was the most uncomfortable frame. It just didn't last very long.\" The experience of owning a black metal frame has turned off a large majority of consumers who would have found happiness and delight in owning solid wood frames made to last. It's really a shame as futons offer great flexibility in being both sofas and sleepers.
Anna Burris Futon, 2018-04-20 04:19:49. At first it was widely regarded as a great addition to the futon family of products. Finally, a futon that could be offered at a much a lower price point. Black metal frames were being imported from China, Malaysia and Taiwan. Many of the early black metal frames were packaged with an import mattress made up of ground up textile materials and a colored covering with tufts. These packages were often anywhere in price from $199 - $249 and started out in specialty futon shops as a great way to introduce customers on a budget into a lower priced futon option. It was soon discovered though that these frames were not such a bargain that they appeared to be.
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Here in Leeds, Health Visitors work as part of Early Start Teams with Children's Centre staff to make the early support, we give to families in their local community, more joined up and focussed around your needs.
The Health Visiting Team aims to provide:
Often from the 30 week in pregnancy, which provides an opportunity for assessment and building a relationship by getting to know you and your family before the baby has arrived as well as making the most of a time when parents are particularly receptive to learning and to making changes.
Preparation for birth and beyond is an antenatal course offered to first time parents. The sessions are delivered by Health Visitors Midwives and Family Outreach Workers in local Children's Centres across Leeds.
The programme involves six sessions that will help parents to understand their baby and prepare for the physical and emotional changes for them and baby before and after birth. The themes include:
To find out more please ask your midwife or contact your local health visiting team
Usually when the baby is about 2 weeks old which builds on the relationship developed from our first meeting and to support and develop skills and confidence in new parents by sharing information on family and child health issues.
To continue developing the relationship which allows for an open and honest exchange of information which enables parents new skills and confidence to be acknowledged and appreciated by the health Visitor, and if necessary to challenge from a position of trust and genuine respect for one another
Will be offered by the Health Visiting team normally by a Community Nursery Nurse. These are offered at 8 – 12 months and 2 -2.5 years with a participative assessment form that parents complete with their child called the Ages and Stages Questionnaire. This is a set of questions about what your child is (or is not) able to do, so that your expert knowledge is included in the conversation. For more information about completing the ASQ, please click on the link below.
If your child attends an early years setting then the Early Year's Progress Check will be combined with the development review completed by the health visiting service, when your child is 27 months - this is called an Integrated Review. For more information about the Integrated Review, please click on the link below.
Having a child comes easily to some parents, where for others the adjustments can be difficult. Health visitors work with all parents to assess the support they need and develop appropriate programmes to help give the child the best possible start in life.
In Leeds, Health Visiting, as part of the Early Start Service, is a way of delivering family focused health, early learning, care and support across Leeds. We do continue to work closely with our other health colleagues such as Midwives, GPs, hospitals and specialist support centres. Access to drop in clinics and groups that are running across the city is open to all families and most of them within children's or health centres where other services can also be obtained.
We all aim to work in partnership with parents to promote positive parenting practice that provides the best possible outcomes for children in Leeds.
Health visitors lead the delivery of the Healthy Child Programme (HCP) as part of the Early Start service. The HCP is the evidence-based public health programme for children and young people, which provides a range of health interventions and support, for families from pregnancy through to a child entering school after their 4th birthday. Health visitors in Leeds play a crucial role in ensuring that families get good joined up support at the start of life.
Midwives refer to the Health Visiting Service during pregnancy and we are notified by GPs and children's centres if recently moved into the local area.
You can also refer yourself to the service if your child is under 5 years of age. Find out who to contact using the postcode locator tool on the Family Information Service website.
From the 1 November 2017 Health Visiting admin support came together from across the city into one Single Point of Access:
You can check where your health visiting team is based by visiting the Family Information Centre and entering your postcode into the Early Start Search. See link below
Health Visit Single Point of Access:
0113 8435683
Health Visiting Admin
Floor 3
Stockdale House
Victoria Road
This booklet is available to order from Harlow Printing. Please contact them on 0191 455 4286 or email firstname.lastname@example.com
"The biggest thing I took away was - everything in moderation"- Mizbah, 37, attended The LEEDS Programme after bein… https://t.co/joXkgesIj6
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If you have used this service in the past, and would like to provide us with feedback as part of the NHS "Friends and Family Test" (FFT) please select one of the links below:
To access and complete the FFT click here >
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The information you provide will be used to inform how better we can deliver the service.


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At the beginning of the circuit the hot source is connected to the common terminal on SW1. The neutral is spliced to the white cable wire and then spliced to the neutral terminal at L1, along with the white 2-cable wire running to L2 where it connects to the neutral terminal.
In a kitchen where only one outlet box is available and both a switch for a garbage disposal and a gfci receptacle are needed, a a switch/gfci combo can be used as in the diagram at this link.
If your switches stop working they may be worn out or the screws may have come loose. If you've wired a new switch correctly and the circuit still doesn't work, the switch may be defective. Check that all connections are tight. Check the switch, remove it from the circuit and test for failure with a continuity tester or multimeter set on the Ohms setting.
This diagram illustrates wiring for a 4 way circuit with the electrical source at the light fixture and the switches coming after. Two-wire cable is run from the light to SW1 and 3-wire cable runs between all the switches. The hot source is spliced through to the common terminal on SW2 and the hot terminal on the light fixture is connected to the common on SW1. The travelers run from SW1 to T1 on the 4 way and from T2 to the travelers on SW2. Note that the white wire is wrapped with black electrical tape when it is used for hot in these circuits.
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text:
Journal Articles
- Author
- Gabel Steven
- Journal
- Facial Plastic Surgery Clinics of North America SCI(E) SCOPUS
- Publisher
- Elsevier in 2013
- Cited Count
- 0
- Partners
- Elsevier
- 10.1016/j.fsc.2013.06.002
- Paid
- Elsevier
- Library Links
- 서울대학교 인하대학교 서울대학교 의학도서관 settings
- Category
- Medicine > Plastic Surgery
- Keywords
- Megasession, Large sessions, Graft survival, Hair transplantation, Follicular unit grafting, Patient selection, Complications, Patient expectations, Surgical techniques
- Abstract open button
- References open button
Surgical hair restoration allows male and female patients to achieve aesthetically natural results. The term megasession refers to transplanting greater then 3000 follicular unit grafts in a single procedure. By transplanting a large number of grafts, megasessions are capable of definitively treating a significant area of the scalp in 1 session. Patients must be carefully selected to determine whether they are appropriate candidates for an extended procedure. An experienced and well-organized surgical team is mandatory to meet the demands of this technically challenging and lengthy procedure. This article reviews the indications, contraindications, and technical perspectives surrounding megasession hair transplantation.
References 15
1.Megasession: excision of numerous skin cancers in a single session. Dermatol Surg. Vol. 31. 757761(2005) Martinez J.C. et al.
2.Micrografting in Extensive Quantities(1995) WILLIAM R. RASSMAN et al. Dermatologic SurgeryDermatology cited 5 times
3.Transverse Microscopic Anatomy of the Human Scalp(1984) John T. Headington Archives of DermatologyDermatology cited 64 times
4.Elliptical donor stereoscopically assisted micrografting as an approach to further refinement in hair transplantation. Dermatol Surg. Vol. 20. 789793(1994) Limmer B.L.
5.Micrograft and Minigraft Megasession Hair Transplantation Results after a Single Session(1997) Barrera, A. Plastic and Reconstructive SurgeryPlastic Surgery cited 11 times
6.The Aesthetics of Follicular Transplantation(1997) Bernstein, R. M. et al. Dermatologic SurgeryDermatology cited 28 times
7.Graft anchoring in hair transplantation. Dermatol Surg. Vol. 32. 198204(2006) Bernstein R.M. et al.
8.Mega session follicular unit transplantation. Hair transplantation. 363371(2011) Wong J.
9.Scalp elasticity scale. Hair Transplant Forum Intl. Vol. 15. 122123(2005) Mayer M. et al.
10.Micrograft survival. Hair replacement. 147149(1996) Limmer R.


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Latest Weather Blog
Shoplifter arrested after 28-mile pursuit
BATON ROUGE- A slew of law enforcement helped tackle a suspected shoplifter who tried to evade authorities in three parishes Monday.
The unnamed man was apprehended at the intersection of Lee and Nicholson in Baton Rouge following a pursuit from Gonzales. Police in Gonzales said the man stole from a store in the Tanger Outlet Mall and was followed by Gonzales Police into Iberville Parish and eventually East Baton Rouge.
Iberville Parish deputies arrested the suspect in East Baton Rouge and turned the man over to Gonzales Police, the department's spokesperson, Charlotte Guedry, said.
A number of officers filled the parking lot of a gas station at the intersection in Baton Rouge where the pursuit ended.
Authorities said the man left the shopping center and took Highway 30 into Iberville Parish and continued on it until it became Nicholson in East Baton Rouge. Officers from Gonzales, St. Gabriel and Iberville where involved in the pursuit as it entered East Baton Rouge, Guedry said.
Details about the suspect have not been released.
Follow the publisher of this post on Twitter: @treyschmaltz
More News
Desktop NewsClick to open Continuous News in a sidebar that updates in real-time.
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LSU begins digitizing century-old editions of longtime campus newspaper
Hundreds of volunteers pick up litter around the capital city
New entertainment venue set to open at Mall of Louisiana in 2019
Cheeky Capitol parking lot security system strikes again
Denham Springs adds second resource officer to watch its schools


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Estate Sales Around Laguna Beach, CA
94 estate sales currently listed near Laguna Beach, California.
Caring Transitions of South Orange County warmly welcomes you to our Irvine Vintage & Mid-Century Modern Online Estate Sale Auction, our first sale on the BRAND NEW CTBids.com! Like the name suggests, this sale features many fantast...
Quick Solana Beach Online Estate Sale Out Of Home Closing This Thursday 6/21. https://www.savacoolandsons.com/auction-1118.html?title=Quick+Solana+Beach+Online+Estate+Sale+Out+Of+Home+Closing+This+Thursday+6%2f21 WE SHIP! -- LOCAL PICK UP IS FRE...
WILL SELL by Thursday June 21, 2018 8:00 PM Los Angeles Downsizing Online Auction - Carmona Avenue This online auction features artworks, Modern Wood Frames, glassware, decors, collectibles, bakeware, jewelry, Scuba Pro Dive Mask and much more. Ple...
Caring Transitions of Carlsbad & LaJolla is proud to invite you to our Oceanside Estate: Furniture & Collectibles Online Auction! This sale includes furniture, Thomas Kinkade collectibles, electronics, china, perfume bottles, jewelry, home deco...
Grasons Co. South Bay would like to invite you to another great 2 day estate sale in Manhattan Beach. This house has a little something for everyone. Here are just some of the great items we have for sale this weekend: Jewelry Vintage Budweise...
Hello Friends, Grasons Co. Beach Cities is honored to present you with a cute 2 day estate sale in downtown Huntington Beach. Our sale will only be happening this Thursday & Friday from 9am till 2pm. You will find a little something for every...
NO LIST WILL GO UP. FIRST COME FIRST SERVED. Cash and Credit card accepted (On total purchase of $25.00 or more). ALL SALES ARE FINAL, please inspect all items before you purchase. EVERYTHING SOLD AS IS. Please bring your own ba...
Caring Transitions Inland Empire Foothills warmly presents our "Upland High-End and Chic" Estate Sale! Dates & Times: Friday, June 22nd 8:00am to 3:00pm No sign-up sheet or numbers. First come, first serve. Cash and credit card...
Stunning Home in the Santa Rosa Plateau Communities in the Hills of Murrieta: Monumental Life Size Classical Silvered Bronze Statues by S. Keliam Bronze Statues: Isis by Colinet, Descara and more Italian Wall Sconces Bavienthal Tea Set Artwork: ...
Beautiful Furnishings Art Decor & More. Heritage Furniture including a beautiful buffetMid-century end tables & coffee tableHoward Miller Grandfather ClockStunning Thomasville Italian inspired bedrooms set including Amoire & king bedLazyboy el...
Incredible sale you won't want to miss! This original Santa Ana Family saved everything!Toys from the 1950's-1980's in box! Full garage, full kitchen! Tools, ceramics, 2 storage sheds full of collectables! 100's of Precious Moments. Typewriters,...
Furniture, pitchers, decanters, animal figures, XXL and XL clothes, SO MUCH ART, Turntable, Lladro, NIB gifts, backpacks, tennis rackets, linens, statuettes, patio decor, books, LOTS OF STUFF. More pics later. ...
Furniture throughout home including Antiques, Mirrors and Lamps Refrigerator Kitchen items including Pyrex and Corning Ware Garage items Women's Clothes
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Thousands of things in one small condo! Train sets, cut glass, decanters, ceramics, 100's of Hallmark Keepsake Christmas ornaments ($1), vintage frames, old postcards, glassware, crystal, records, books, typewriter, turntable, furniture, ta...
Homeowners ; Entertainment Lovers Delight Moving Estate Sale!! This sale features everything you need to entertain in your place from smart TVs, outdoor furniture and accessories tools and more!
Calling on all who will need anything and everything to keep your home cozy, smart and well maintained. This is a household moving sale. This home has available to you cozy sofas, decorative chairs, side tables and lamp, artistic art photos and ...
Thursday June 21 8am to 1pm Saturday June 23, 2018 7am to 1pm NO SALE FRIDAY Last Minute Palos Verdes Estates, Sale By PickersRUs HOUSE MUST BE CLEARED THIS WEEKEND THANKS FOR LOOKING Luthe...
Hi Everyone! Remember to bring heavy lifters with you or have them on standby. No bags or large purses will be allowed. Lines will move slowly when we have a house packed with goodies, please bring your patience. Importan...
This fabulous home has amazing furniture - lovely home decor, interesting household items and an AMAZING. Assortment of fine jewelry, semi precious sterling and pretty pieces of costume jewelry. Join us this Friday from 9 to 1 and Saturda...
Hello Friends, Grasons Co. Newport Beach is honored to present you with this awesome One Day Only Estate Sale in one of the most beautiful homes in Back Bay Newport Beach. This is a last minute sale due to timing, house will be demolished soon for a...
Hello friends, Welcome to another Spectacular Grasons Co. Elite 3 Day Estate Sale. We are honored to have been chosen to perform the sale for the wonderful family. This home is complete with vintage and antique Asian collectibles, furniture, t...
Nationally Featured Estate Sales & Auctions
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New Neurodevelopmental Syndrome Identified
News Apr 22, 2016
A multicenter research team led by Columbia University Medical Center (CUMC) has discovered a new neurodevelopmental syndrome and the genetic mutations that cause it. The discovery is an important step toward creating targeted therapies for individuals with this syndrome, which causes severe developmental delays, abnormal muscle tone, seizures, and eye complications.
The study was published online in the American Journal of Human Genetics.
"Now that we've determined that a small subset of patients with neurodevelopmental disabilities share the same mutations, we can begin to learn about the prognosis of these individuals, how these mutations lead to this syndrome, and how to develop targeted therapies," said study leader David B. Goldstein, PhD, the John E. Borne Professor of Medical and Surgical Research (in Genetics and Development) and director of the Institute for Genomic Medicine at CUMC.
The discovery was made by performing whole-exome sequencing of patients with an undiagnosed neurodevelopmental disorder to identify excess spontaneous, or non-inherited, mutations. (The exome is the portion of the genome that encodes for the production of proteins.)
"Of the hundreds of patients we sequenced at CUMC, three were found to have mutations in a gene called GNB1," said Slave Petrovski, PhD, former research scientist with the Institute for Genomic Medicine at CUMC and the first author of the report. "We then reached out to our colleagues at other medical centers to see if they found similar mutations in any of the patients whose DNA they had sequenced. In all, we reviewed sequencing data on 5,855 individuals and found a total of 13 individuals with GNB1 mutations."
GNB1 mutations have been detected in some cancers, but this is the first time the mutations have been linked to a neurodevelopmental disorder. GNB1 encodes a protein that functions in the transmission of many different kinds of signals within cells.
"As of yet, we don't know which aspect of that signaling is affected by these mutations," said Dr. Goldstein. "Moving forward, we hope to determine exactly how these mutations cause disease and then use that information to identify druggable targets—completing the entire precision medicine circle for this condition, from gene discovery to functional biology to the development of targeted therapeutics."
Whole-exome sequencing is currently not a standard part of the evaluation of patients with neurodevelopmental disorders. "With more discoveries like this one, this genetic approach to disease diagnosis will become standard practice for all patients with these disabilities," said Dr. Goldstein.
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Ancient Syphilis Genomes Decoded for First Time
News Jun 22, 2018


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