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Hormonal Contraceptive Agents/Dabrafenib Interactions
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Medical warning:
Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
Dabrafenib may speed up how quickly your liver processes hormonal contraceptive agents.
What might happen:
Hormonal contraceptive products (such as "the pill", the "mini-pill", Norplant, birth control injections, and the patch) may not prevent you from becoming pregnant while you are taking dabrafenib. If you take dabrafenib while pregnant, it may cause birth defects or a miscarriage.
What you should do about this interaction:
You should not rely on a hormonal contraceptive agent as your only method of birth control while taking dabrafenib, for two weeks after stopping dabrafenib, or for four months after stopping combination therapy with dabrafenib and trametinib. Discuss birth control options with the doctor that prescribed dabrafenib for you and/or with your gynecologist (OB/GYN). If you think that you may be pregnant, contact your doctor right away.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
- 1.Tafinlar (dabrafenib) US prescribing information. GlaxoSmithKline June, 2016..

subset: commoncrawl


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Ek Sach…this short film basically describe few minor things and mistakes of daily life.
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To the editor:
This community never ceases to amaze me! We find ways to work together, support each other, and get things done. Thank you to the Mancos Mill Levy Committee for the countless hours and hard work put into this process. Thank you to the community for engaging in conversations around the Mill Levy and what it would mean for our community. Thank you to the community for supporting the Mill Levy! Thanks for valuing our kids and their education, supporting the Mancos staff, and nurturing programs and opportunities.
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Hormonal Contraceptive Agents/Boceprevir Interactions
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Medical warning:
Serious. These medicines may interact and cause very harmful effects. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
How this interaction occurs is not known.
What might happen:
Hormonal contraceptive products (such as "the pill", the "mini-pill", Norplant, birth control injections, and the patch) may not prevent you from becoming pregnant while you are taking boceprevir. Boceprevir is used with another medicine, ribavirin, which may cause birth defects.
What you should do about this interaction:
You should not rely on a hormonal contraceptive agent as your method of birth control while taking boceprevir. Discuss birth control options with the doctor that prescribed boceprevir for you and with your gynecologist (OB/GYN). You should use two other methods of birth control (such as an intrauterine device [IUD] and/or barrier methods) while taking boceprevir and ribavirin and for six months after finishing your therapy. Be sure to undergo a pregnancy test every month. If you think that you may be pregnant, contact your doctor right away.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. Do not start, stop, or change the dosage of any medicine before checking with them first.
- 1.Victrelis (boceprevir) US prescribing information. Schering Corporation January, 2017..


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Blaine T. Phillips Distinguished Professor of Environmental Law
Hunton & Williams Professor of Law
Director, Environmental and Land Use Law Program
J.D., University of Pennsylvania Law School, 1974
B.A., Williams College, 1967
Jonathan Cannon, director of the Law School's Environmental and Land Use Law Program, joined the Law School faculty in 1998 from the Environmental Protection Agency, where he served as general counsel (1995-98) and assistant administrator for administration and resources management (1992-95). Prior to his work with the EPA, Cannon was in the private practice of environmental law; served as an adjunct professor at Washington and Lee Law School, where he taught environmental law; and was a lecturer at the Law School.
Cannon is the author of the new book, "Environment in the Balance: The Green Movement and the Supreme Court."
Environment in the Balance: The Green Movement and the Supreme Court (forthcoming, Harvard University Press 2015)
"Taking Enforcement on Its Own Terms: EPA's Heavy-Duty Diesel Engine Litigation," 5 Reg. & Governance 262 (2011).
"The Sounds of Silence: Cost Benefit Canons in Entergy Corp. v. Riverkeeper, Inc.," 34 Harv. Envtl. L. Rev. 425 (2010).
SSRN | HeinOnline (PDF)
"America's Energy Future: Balancing Renewable Power and Carbon Fuel" (with Michael R. Bucy), Miller Center, University of Virginia (April 2009).
"Respecting EPA: Restraining Presidential Influence in EPA Decisionmaking Leads to Better Environmental and Political Outcomes," 39 Envtl. L. Rep. 10080 (January 2009).
"Over the Life of a Site," Envtl. F., Sept./Oct. 2008, at 27.
"Sustainable Watersheds," Commentary, 107 Mich. L. Rev. First Impressions 74 (2008).
"A Bargain for Clean Water," 17 N.Y.U. Envtl. L.J. 608 (2008).
SSRN | HeinOnline (PDF)
"Adaptive Management in Superfund: Thinking Like a Contaminated Site," in G. Macey & J. Cannon, eds., Reclaiming the Land: Rethinking Superfund Institutions, Methods, and Practices 49 (Springer, 2007).
"Reclaiming the Land: Rethinking Superfund Institutions, Methods, and Practices" (editor with G. Macey) (Springer, 2007).
"Words and Worlds: The Supreme Court in Rapanos and Carabell," 25 Va. Envtl. L. J. 277 (2007).
HeinOnline (PDF)
"The Significance of Massachusetts v. EPA," 93 Va. L. Rev. In Brief 53 (2007).
"Checking in on the Chesapeake: Some Questions of Design," 40 U. Rich. L. Rev. 1131 (2006).
HeinOnline (PDF)
"Environmentalism and the Supreme Court: A Cultural Analysis," 33 Ecol. L. Q. 363 (2006).
HeinOnline (PDF)
"Adaptive Management in Superfund: Thinking Like a Contaminated Site," 13 N.Y.U. Envtl. L.J. 561 (2005).
HeinOnline (PDF)
"Presidential Greenspeak: How Presidents Talk About the Environment and What It Means" (with Jonathan Riehl), 23 Stan. Envtl. L.J. 195 (2004).
HeinOnline (PDF)
"How Local Environmental Laws Can Further Federal Environmental Goals," in John R. Nolan, ed., New Ground: The Advent of Local Environmental Law (Environmental Law Institute, 2003).
"Bargaining, Politics and Law in Environmental Regulation," in Environmental Contracts: Comparative Approaches to Regulatory Innovation in the United States and Europe (Kluwer Law International, 2001).
"EPA and Congress (1994-2000): Who's Been Yanking Whose Chain?," 31 Envtl. L. Rep. 10942 (2001).
"Choices and Institutions in Watershed Management," 25 Wm. & Mary Envtl. L. & Pol'y Rev. 379 (2000).
HeinOnline (PDF)
"Geographic Approaches to Environmental Management: Bioregionalism Applied," in Proceedings, Watershed '93: A National Conference on Watershed Management (March 1993).
"Superfund Liability Provisions: Impact on the Industrial and Insurance Sectors," in U.S. Waste Management Policies: Impact on Economic Growth and Investment Strategies (American Council for Capital Formation, Monograph Series on Tax and Environmental Policies and U.S. Growth, May 1992).
"Superfund Transaction Costs" (with W.N. Hedeman and D.M. Friedland), Vol. XXI, No. 7 Envtl L. Rep. (1991).
"Rethinking RCRA for the 1990s" (with M.E. Williams), Vol. XXI, No. 2 Envtl L. Rep. (1991).
All Courses
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In the Media
- "Standing, Administrative Law Define Scalia's Legacy" (Bloomberg BNA, 02/17/2016)
- "Observers: Without Scalia, Clean Power Plan's Odds Boosted" (Bloomberg BNA, 02/17/2016)
- "How The Paris Climate Agreement Super-Charges The Clean Air Act" (Think Progress, 01/14/2016)
- "Broken Process Imperils Obama EPA Nominees' Chances" (Bloomberg, 12/18/2015)
- "Justices Agree Cost Matters, but Differ as to When" (ACOEL.org, 06/30/2015)
- "Supreme Court Blocks EPA's Mercury Rules" (Inside Climate News, 06/29/2015)
- "The Source: The Supreme Court's Historical Role in Environmental Protection" (The Source, 05/04/2015)
- "So the U.S. and China Made an Historic Climate Agreement. Now What? (Newsweek, 11/12/2014)
- "Nice guys finish ... second" (Greewire, 02/27/2014)
- "For Ken Cuccinelli, Losing Big Cases Won't Work Forever" (The Washington Post, 06/30/2012)
- "Chesapeake Bay Case Settled With Nation's Largest Water Cleanup Plan" (Environmental News Service, 05/11/2010)
- "EPA Studying Own Carbon-Trading System, Official Says" (Bloomberg News Service, 03/15/2010)
- "Filling Void Left by Congress, States Take on Carbon Trading" (Bloomberg News Service, 01/11/2010)
- "States Expected to Lead Carbon Markets as Federal Plan Stalls" (Business Week, 01/07/2010)
- "Sotomayor's Record on Enviro Issues Faces Scrutiny as Hearings Begin" (Greenwire, 07/13/2009)
- "Environment Groups Find Less Support on Court" (The New York Times, 07/03/2009)
- "High Court Losses Stun Environmentalists" (The National Law Journal, 06/29/2009)
- "Many of the 'Hands-On' Positions in Obama Administration Going to Law Professors (The National Law Journal, 02/25/2009)
- "EPA Missing in Action on Major Environmental Issues, Observers Charge" (Government Executive.com, 04/14/2008)
- "Supreme Court 'Pre-Emption' Cases Cast Shadow over Enviro Regs" (Greenwire, 10/05/2007)
- "Court Takes Up Landmark Wetlands Case" (Associated Press, 10/11/2005)
- "Roberts' Questionnaire, History Offer Little Insight into Enviro Philosophy" (Greenwire, 08/03/2005)
- "Supreme Court Debates Pollution Cleanup Lawsuits" (Associated Press, 10/06/2004)
- "Residents Battle Proposed Jet Field" (The Virginian-Pilot, 03/08/2004)
- "E.P.A. Says It Lacks Power to Regulate Some Gases" (The New York Times, 08/29/2003)


text:
Call to end stop and search 'abuse'
Stop and search powers should be scrapped entirely after 40 years of alienation, a campaigner has claimed, despite moves by the Home Secretary and police forces to increase transparency.
Ken Hinds, of Haringey Stop and Search Monitoring Group, said he had been stopped by officers more than 120 times in the past 30 years, accusing officers of using racial profiling.
The Metropolitan Police have pledged to sign up to a new voluntary code of conduct for all police forces on stop and search, which will see data published on all outcomes from uses of the new powers.
The Metropolitan Police is to publish the results of stop and search incidents
The changes are being brought in after Her Majesty's Inspectorate of Constabulary (HMIC) found that 27% of stop and searches did not contain reasonable grounds for suspicion, meaning that more than 250,000 of the one million searches carried out last year could have been illegal.
In addition, black and minority ethnic (BME) members of the public were up to six times more likely to be searched than white people.
But Mr Hinds, speaking on the BBC Radio 4 Today programme, said he did not think reforms would be effective.
He said: "I believe after 40 years of abuse of stop and search - we now refer to it as stop and scarred in our community - what's happened is it has alienated whole swathes of communities.
"They cleverly keep saying stop and search is used for getting knives and guns off our streets. If that's the case, why is it, out of 1.2 million stops that you have, only 6% is used to target weapons?
"Come on... we have 40 years of scarring and I'm saying you cannot expect communities affected by it to say OK."
Speaking on the same programme, Chief Constable Alex Marshall, of the College of Policing, defended the powers.
He said: "Stop and search is a really important power to protect local communities from people carrying weapons, who are carrying stolen property, from drug dealers moving their drugs about.
"But in many cases, the person stopped and searched does not have anything on them and that stop and search must be carried out with respect and courtesy.
"Then the evidence shows people will support the use of stop and search if it is well targeted and is carried out with respect."
Mr Marshall said a black man driving an expensive car would not be reasonable grounds to carry out a search - despite Mr Hinds' reports of his own experience.
The Chief Constable said the new data published under the code of conduct would set standards of policing and help to redesign training.
Home Secretary Theresa May announced the Best Use Of Stop And Search Code Of Conduct after admitting that the power had been misused in the past.
Under the scheme, police forces who sign up voluntarily will agree to more limits on blanket Section 60 stops, used on the anticipation of serious violence without suspicion that a person is carrying weapons, while better records will be kept of each instance and published online.
The Met said it was introducing those two elements of the new plan from today and comes after Section 60 searches were used as a tactic in combating violent crime at this year's Notting Hill Carnival.
Last year 47,141 arrests were made as a result of stop and search, representing 20% of total arrests by the Met, and, of the 251,161 people who were stopped and searched from August 2013 to July 2014, 115,270 (46%) were white, 72,016 (29%) were black and 34,267 (14%) were Asian. Men accounted for 94% of all searches.
Commander Adrian Hanstock, the Met's lead for stop and search, said in a statement: "The Met has made significant improvements to stop and search over the last two years to not only reduce the total number of people we search, but also to ensure that our officers focus on those areas and types of crime that the public are most concerned about.
"As a result, we are arresting more people than ever before following the more targeted use of stop and search and routinely find people in possession of weapons and stolen items.
"In line with the Best Use Of Stop And Search scheme and our commitment to increase transparency and accountability, the MPS has today introduced a new approach to Section 60 authorisation and has introduced revised recording of stop and search outcomes."
Speaking in the House of Commons when announcing the shake-up in April, Mrs May said misuse of the power damaged public trust in the police.
She said: "While it is undoubtedly an important police power, when it is misused stop and search can be counter-productive.
"First, it can be an enormous waste of police time. Second, when innocent people are stopped and searched for no good reason, it is hugely damaging to the relationship between the police and the public. In those circumstances it is an unacceptable affront to justice."
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If a Tax Invoice has been successfully generated from the South African Airways Tax Invoice System, the onus rests on the recipient to ensure that his/her mailbox has enough space to receive an e-mail - with a PDF attachment; and that his//her service provider or exchange server allows for delivery of such e-mails. South African Airways, can not take responsibility for undelivered e-mails due to any other reasons beyond our control including the above.
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Tax invoices must ordinarily reflect the following details as prescribed by the South African Revenue Service Act, 1997 (Act No. 34 of 1997):
South African Airways (SAA) announces additional flights to Mumbai
Johannesburg, 8 May 2012. South African Airways (SAA) is pleased to announce the introduction of additional flights between Johannesburg and Mumbai following increased demand on this very popular route.
Effective 16 June 2012 the airline will be offering five flights per week between the two cities, which is one flight per week more than currently on offer. The additional flight is subject to government approval.
In addition, SAA will be introducing a bigger aircraft on selected days in order to accommodate the additional demand. The airline is currently using the A330-200, one of its newest aircraft with 36 business and 186 economy class seats.
The airline hopes to be adding even further flights on this route in the near future as travel between South Africa and India has recently shown noticeable growth.
"These initiatives demonstrate our commitment to the Indian market, which we will continue to serve and grow in line with customer demand," says Theunis Potgieter, SAA General Manager Commercial.
Schedule Johannesburg to Mumbai (as from 16 June):
00h35 following day
07h55 same day
For further information please contact Kabelo Ledwaba, SAA Manager External Communication on 083 414 4720.
About SAA
South African Airways (SAA) is the leading carrier in Africa, serving 20 destinations across the continent, as well as major destinations within South Africa, from its hub, Johannesburg. It is a member of the largest international airline network, Star Alliance. SAA's core business is the provision of passenger airline and cargo transport services together with related services, which are provided through SAA and its four wholly owned subsidiaries: SAA Technical; Mango its low cost carrier; Air Chefs, the catering entity of SAA and South African Travel Centre (SATC). SAA CEO Siza Mzimela is the first woman to be appointed into the IATA Board of Governors in its 67 year history. SAA is the winner of the 'Best Airline in Africa' Award in the regional category for 9 consecutive years and the winner of 'Service Excellence Africa' for two consecutive years. Mango and SAA hold the number one and number two successive spots as South Africa's most on time airlines.