text:
Janesville Police Department awards top employees
JANESVILLE--The Janesville Police Department honored its 2013 department award recipients with a reception in March.
The department issued the following information about the award winners:
-- Officer Chad L. Woodman, Meritorious Service Citation for subduing a man armed with a butcher knife.
Woodman responded to a violent domestic dispute in which a father was beating a mother and had armed himself with a knife. Woodman saw the children of the couple outside the home and told them to run down the street and hide until other officers arrived.
When the father exited the house holding a butcher knife, he refused to drop the knife and would not comply with Woodman's commands. After further commands were ignored, Woodman used his Taser to incapacitate the man and took him into custody.
The man was arrested for four criminal charges.
During the event, Woodman ensured the safety of the two children, the victim and himself and safely took the suspect into custody. Woodman's actions reflect his ability to perform under stress while utilizing his training, according to the department release.
Woodman has been employed by the department since 2000. He works third shift patrol and is a sniper on the SWAT team. Woodman was awarded a Chief's Commendation for an incident he responded to in October 2013.
-- Officer Shane A. Punzel, Police Officer of the Year. Punzel has been an officer with the department since 1996 and works first shift patrol. In addition to his duties as a patrol officer, Punzel is a member of the SWAT team and is a firearms instructor.
-- Karen E. Burdick, Civilian Employee of the Year. Burdick joined the department in 1997 as an administrative aide, moved to the position of records manager in 2009 and currently is the chief's secretary.
In 2013, Burdick managed the changeover to the department's new records management system. She assisted in the selection of the new system by serving on a countywide committee, formed in 2009. She spent hours designing the system to meet the needs of the Janesville Police Department, along with preparing and entering all the necessary data to ensure a smooth transition from the old to the new system.
-- Lt. Terrence E. Sheridan, Award of Excellence. Sheridan joined the department as an officer in 1992. He is assigned to third shift patrol.
Since his promotion to lieutenant in 2010, Sheridan has worked on technology initiatives for the department.
Sheridan also manages the field training officer program. He recently updated the program to include problem oriented policing tactics. In conjunction with the field training program, he oversees all background investigations conducted for police officer candidates.
-- Officer Benjamin G. Biddick, Problem Oriented Policing Award. Biddick was hired by the department in 2010 and works third shift patrol.
In the fall 2013, the north side of Janesville experienced a string of residential burglaries. Biddick designed a residential security notice to be left at homes where unlocked doors or vehicles were found. By making residents more aware of security, it is likely that burglaries to those homes will be prevented, according to the release.
-- Officer Bradley T. Rau, Problem Oriented Policing Award. Rau joined the department in 1999 and works first-shift patrol.
Starting in 2011, the Rock County area started to see an influx of live musical events at bars featuring musical acts from out of the area. Such an event in the town of Beloit ended with a fatal shooting involving a town of Beloit officer in 2011.
During a similar event in Janesville in 2012, an altercation occurred in the parking lot and one gunshot was fired. During two similar events in Newville in 2013 and 2014, one person was shot each time.
Recognizing the trend of violence surrounding these events, Rau met with a local bar that often hosted similar events and worked with the bar owner to review safety practices. Suggestions were made to help increase both patron and officer safety. After continued meetings with the bar owner, no major incidents have occurred during events at this bar over the past two years.
-- Kealey Pharmacy, Law Enforcement Service Award: Business. Kealey Pharmacy, Janesville's only independently owned pharmacy, is an active participant in the Rx Alert program. Rx Alert is a cooperative effort to increase communication between the Janesville Police Department, local pharmacies and health care providers to reduce prescription drug violations. The pharmacist and employees of Kealey Pharmacy use the information provided by Rx Alert to recognize potential abuse cases and act on them accordingly.
In April 2013, the department received information on several out-of-state individuals attempting to pass prescriptions for narcotics at local pharmacies. Mark Johnson, owner of Kealey Pharmacy, received a call from an individual asking to have an out-of-state narcotic prescription filled. Based on the information obtained through Rx Alert, employees notified police and a suspect was taken into custody for a prescription drug offense. A similar incident in the spring of 2013 led to the arrest of a Janesville female who was attempting to pass fraudulent prescriptions.
-- Brian W. Iverson, Law Enforcement Service Award: Citizen. On Oct. 26, 2013, Iverson confronted an intruder in his home. During the confrontation, Iverson sustained injuries to his left eye and elbow.
Janesville police officers were in the area investigating a complaint of a burglary from a nearby home. Officers arrived and took the suspect into custody. The suspect was arrested on multiple charges. Iverson's actions resulted in the capture and arrest of the suspect.


text:
The Fiber Disease
Human Anatomy, Physiology, and Medicine. Anything human!
Moderator: BioTeam
Antibitotic "Doxycycline" does not eradicate the organism. I took for over 1 1/2 years. It certainly made me feel better. I believe it reduced overall inflamation. In time I came down with Rosacea and fungal infection in mouth. Had to stop antiobiotic. My weight goes up and down rapidly and I now wonder if it has to do with the number of these things infesting the entire body. My weight can fluctate as must as 30% of the overall.
Best is to understand that most people have tried various combinations or long courses of anti microbial agents without being able to eradicate this infection.
Because of this fact it is likely that a trypanosome has been used. Infection eradicated, patient has died! This counts in africa until today...
About weight;
As far as I do remember doxycycline is an additive to e.g chicken and pig feed. It causes rapid gain of weight (growth promotor)
Swine practice///
Tetracycline resistance
Tetracyclines (tetracycline, doxycycline, minocycline, oxtetracycline, . ... human and veterinary medicine but also as growth promotor in animal husbandry. ...
http://www.antibioresistance.be/Tetracy ... u_Tet.html - 9k - Cached - Similar pages
Sky (and all) you say if we keep our bacteria down, we can keep the worm down. I was wanting your opinion of whether you think you have a true worm parasite (filarial, Oncho....) Or do you think like I do and think they are alll just synthetic......?
As I said a couple of times before, there is a lot of informaion out on the parasitoid wasp, their toxins on the TG plants, the bee mites, etc.,,,,but if
I had to pick out just one about this aspect of our illness: (the wasp part)
I think the fact that the grain/wheats stored in a warehouse unopened
crates has done the most havoc. Remember, there is an organism that does indeed wrap itself in fibers...
Also, they have used the yeast S cervechei. That;s a fact. And, I dunno if anyone read it (maybe Systemic did) where I posted one that talked about the aspergillis spreading thru Cotton.....so now that would make the candida a part of this. I know that Strep is going to be involved.
Right now, my body shows signs that I have polycythremia vera>>>and NO cure....
Hey Sky, the CDC has Had the wolbachia on it's website for a couple of months now It is under recently emerging diseases......basically, it says this.....that the wolbachia causes Cytoplasmic I....gets into 12 insects...the main one id the flea, the mites, the head lice, etc. Says itwill show itself in 1 of 4 ways
trench fever, a???(heart prob;), CAT-SCRATCH disease>>>>they all all one and the ame >>>>>then, that is another name for AIDS.
Oh hell yeah, I think they are involved (the wasp) but if it did cause this murine Typhus in me> well it showed up 12 mo. lATER, NOt THE ususal 6 days,,,,,, My left forearm is still broke out....How can an insect do my arm like this for 8 Months? I don't think it can, ut I donno.,
It is in the water system, or A?C heat system perhaps as well as the lab
Hi, you asked about how to kill it if this think is antibiotic resistant. ( I never said it was that, but I did say that they are releasing these insecticide resistant pathengens....). Hey, So you are from Sliddel?
Was man-made hurricane not 0bvious of the racist F-sticks we have in running this country......You know, we v
Last edited by London on Mon Sep 11, 2006 1:18 am, edited 1 time in total.
man ....
who in the hell is this "sara" ... i mean damn if this is an example of what comes out of the US medical institutions we ARE DOOMED!!!!!!!!!
her narrowminded, self indulgent perspective on another persons illness has got me googling casket prices. anybody check ebay for grave plots?
and tamtam calm down you are right the communist intervention is real but dont go thrashing your statesmen, Sky troll is on our side, infected or not.
and is there any other case in history that assures us that tams approach will work?
gees how much money are we talking....
cause half the technical procedures could be done at the university by undergrads and as long as we keep the whole adgenda in pieces we wont go down the same path MRF , you know with a few gov. moles to absorb resources with bunk resources to avoid these AMA creeps.
im thinking we should cut off all corrispondance to CDC,AMA,NIH,US GOV.....set array Black Widow Bots on shifting proxy at slow bit rates on their networks get a few in recon and DATA MINE those who DATA MINE us!!!!!!!!!!!!
if they dont shut down the net..... . we could have incriminating evidence within a week .....
what do we have here?.....
until now they were working in the wet lab as molecular biologists and biochemists, now their work will be carried out on computers. Another issue is that the diffraction experiment is within the domain of physics, and while physicists and chemists might be familiar with it, biologists, who were the majority, felt uncomfortable. The students and/or PIs carried out data processing of the oscillation images of those crystals that had interpretable diffraction with close and extensive supervision. They were taught not only how to run the programs, but also the ideas behind them: notions of real and reciprocal space, the physics of diffraction, reflection's intensities and indices, the concepts of unit cell, asymmetric unit, space group, integration, scaling, merging, etc.
Phase determination / structure solution was usually a straightforward procedure since most of the structures were solved by molecular replacement. The only exception was a hypothetical protein (''f'' in Table I) that was solved by multiwavelength anomalous dispersion (MAD). This rather interesting case demanded extra input from the particular group such as growing selenium methionine protein crystals and is described in another part of this manuscript. Structure building and refinement is a procedure that still demands weeks and perhaps months of work. This was accomplished by having the people from the network coming over to the CeBiME for these periods of time. This part helped the students to learn about the protein databank format, atom coordinates, R factor, temperature factor, electron density and many other concepts. Structure analysis would be the final step and as the groups moved towards this, it could be foreseen that difficulties arose when trying to explore completely unrelated structures. Here, there is no clear path to be followed, except for comparing the structures to their homologues when they are present. In most cases some unique features of the proteins will need to be addressed, such as: why is the lysozyme (''b'' in Table I) capable of working in a basic pH, what is the information that the hypothetical protein (''f'') can give about its function or what makes the infestin 4 (''j'') such a good inhibitor of blood coagulation-cascade factor XIIa.
Last edited by Nadas Moksha on Mon Sep 11, 2006 1:48 am, edited 2 times in total.
holy defractions sky troll what do we have here?.....
these students are playing with bio crystallization, common for weaponized pathogens........................
Trypanosomes have a unique RNA processing mechanism and translation initiation control, which therefore constitute interesting drug targets. Most of the genes are transcribed as polycystronic units that are processed by trans-splicing and poly-adenylation. All mRNAs receive a 30-40 nt-capped RNA derived from the splice leader gene in the 5' terminal ends (Gull 2001). Both the cap structure and the enzymes involved in the cap synthesis are different in trypanosomes as compared to mammalian enzymes. For example, a guanilyl transferase of T. brucei has an extra N-terminal portion (Silva et al. 1998) that seems to carry an adenylate kinase domain. The RNA triphosphatase activity is also catalyzed by an unique enzyme (Ho and Shuman 2001). Therefore we selected as targets for structural studies the RNA adenosine triphosphatase from T. cruzi and T. brucei. These enzymes have been cloned, expressed in E. coli, purified, and submitted to crystallization assays. Three conditions were found promising and are used in refinements.
Two targets were also selected for proteins involved in the translation initiation control of trypanosomes. One is the eukaryote translation initiation factor 4E of T. brucei (TBeIF4E), which is the cap-binding protein. It has 251 amino acids and was chosen as a target for two reasons: a) it has only 24% similarity to the mammalian counterpart, thus representing an interesting drug target; b) the structures of the mammalian and yeast homologues have been determined (PDBs:1L8B, 1EJ1, 1AP8), which might help in the analysis of this protein. TBeIF4E was cloned in pET28a, expressed, purified and submitted to crystallization screenings. The other target was the eIF2a of T. brucei. It is a 419 amino acid protein that contains an extension of ca. 120 residues in the N-terminal relative to all other known eIF2a sequences. The same extension is present in T. cruzi and Leishmania major. The complete ORF as well as only the N-terminal half was cloned into pET28a and the protein expressed, purified and submitted to crystallization assays.
SURFACE PROTEINS OF MEROZOITE FORMS OF Plasmodium vivax
We are also interested in the structure of merozoite surface proteins (MSP) of Plasmodium sp, most of them involved in the erythrocyte and reticulocyte invasion. Merozoites correspond to blood stages of the Plasmodium species released by infected cells. These studies can help understanding the biology of these organisms and designing potential agents to block its growth. We have focused on fragments of these major surface proteins, as the entire proteins are too large and insoluble when produced in recombinant form. We expressed fragments corresponding to the C-terminus of MSP3a and the N and C terminus of MSP3b based on the formation of coiled-coil structure as demonstrated (Galinski et al. 1999). Five recombinant proteins were obtained in fusion with His-tags and purified by affinity chromatography and ion exchange. MSP3a e MSP3b have been produced in appropriate levels, purified and submitted to crystallization assays.
We adopted as a general strategy in SmolBNet to select protein targets exclusively related to our current research lines. In a few cases we were successful; this is the case of the trialysin peptides solved by NMR and the serine protease inhibitors solved by diffraction studies. For most of the chosen targets we failed in obtaining structural data,
http://www.scielo.br/scielo.php?script= ... 6000200006
Anais da Academia Brasileira de Ciências - The structural molecular biology network of the State of São Paulo, Brazil
Last edited by Nadas Moksha on Mon Sep 11, 2006 2:13 am, edited 1 time in total.
Protease and Morgellons
Thank you for the welcome. I hope I will be able to offer something to this forum instead of just ask questions.
On the subject of protease, I find it strange that since protease digest protein and insects are protein that they not only continue to thrive in my body but they love the stuff. It leads me to believe that it is the bacteria that poses the greatest risk to our health but yet it seems to be highly resistant to drugs as well as alternative therapies. Is the bacteria protecting the parasite then and or is it the other way around? Do they both give something to the other to survive in our bodies?
I have been able to eliminate all symptoms of this disease and have done it four times on purpose. Each time I get the same results. The first time I was symptom free it took me almost a month to remove all symptoms but when I stopped the treatment it only took 2 days for the biting, lesions and crawling sensations to return. The second time I stopped the treatment it took 3 days for the same symptoms to return and 7 days to stop them again and I repeated that 2 mores times successfully. Then I had increased the protease and within 2 hours the same symptoms returned even though I was still on the treatment but I was able to eliminate them again in 3 days after stopping the protease. To make sure it was the protease 2 days later I took the same dose of protease again along with the treatment and within 2 hours the same symptoms returned. This time it took me 4 days to remove all symptoms. Is it the amount of protease or just protease? I was on a pancreatin formula which supplied 40 mg of Amylase, Lipase and Protease and was able to remove all symptoms with my treatment while on that. The question is was that an acceptable amount to take without increasing my symptoms or was even that amount causing problems and I just had not recognized it yet?
Sorry if I affending anyone with my crack about doctors. Maybe I have just had the wrong doctors. Then again maybe not. Ha HA Ha Sorry.
I think we shall find some answers here.
http://pick5.pick.uga.edu/mp/20q?guide= ... s_Termites
http://www.cvm.okstate.edu/cai/kocan/vp ... ar5333.htm
Want more?
http://www.who.int/programmes/ctd/disea ... lamain.htm
and MORE EVO DEVO......
http://www.ucmp.berkeley.edu/protista/b ... tists.html
SARAH BIONE: one for you......
any need a shovel ?
cause man we got a lot of dirt......................
The principal activity which drives microbivore scaling and design is the process of digestion of organic substances
"the nanorobotic device brings their surfaces into intimate contact, allowing reversible binding sites on the microbivore hull to recognize and weakly bind to the bacterium. Binding sites can already be engineered [77, 78]. Bacterial membranes are quite distinctive, including such obvious markers as the family of outer-membrane trimeric channel proteins called porins in gram-negative bacteria like E. coli [79, 80] and other surface proteins such as Staphylococcal protein A [81] or endotoxin (lipopolysaccharide or LPS), a variable-size carbohydrate chain that is the major antigen of the outer membrane of gram-negative bacteria. Mycobacteria contain mycolic acid in their cell walls [82]. And only bacteria employ right-handed amino acids in their cellular coats, which helps them resist attack by digestive enzymes in the stomach and by other organisms. Peptidoglycans, the main structural component of bacterial walls, are cross-linked with peptide bridges that contain several unusual nonprotein amino acids and D-enantiomeric forms of Ala, Glu, and Asp [83]. D-alanine is the most abundant D-amino acid found in most peptidoglycans and the only one that is universally incorporated [84]. Macrophages have evolved a variety of plasma membrane receptors that recognize conserved motifs having essential biological roles for pathogens, hence the surface motifs are not subject to high mutation rates; these pathogen receptors on macrophages have been called "pattern recognition receptors" and their targets "pathogen-associated molecular paterns"anchorage between the nanorobot and the bacterium assuming a single-lipid extraction force of ~1 pN [1]. In the case of gram-negative bacteria, a footpad with binding sites for ~3 murein-linked covalently attached transmembrane protein molecules would provide a secure 120-480 pN anchorage, assuming 40-160 pN/molecule and ~9 such molecules per 1000 nm2 of microbial surface (Section 3.1.1). In either case, undesired adhesions with bacterial slime must be avoided. The footpad tool is rotated into, or out of, an exposed position from behind a protective cowling, using countercoiled internal pull cables.
The tiniest bacterium to be digested may be ~200 nm in diameter (Section 2.1.4), but the smallest virus can be only ~16 nm wide (Section 2.2). Since the work envelopes of adjacent grapples picking particles bound to the hull surface extend 150 nm toward each other from either side, the maximum center-to-center intergrapple separation that permits the ciliary transport of 16 nm objects is ~300 nm. This requires 1 grapple per 0.09 micron2 of nanorobot surface, for a total of 277 grapple silos uniformly distributed over the entire 26.885 micron2 microbivore outer hull, excluding the two 1-micron2 port doors. (One or more grapple-containing bridges across the annular exhaust port aperture (Section 3.1.4) may be necessary if it is desired to transport targets <200 nm in diameter from the circular DC exhaust port island to the main grapple field of the microbivore, allowing subsequent transport to the ingestion port inlet; such bridges are not included in the present design.) During transport, a bacterium of more typical size such as a 0.4 micron × 2 micron P. aeruginosa bacillus may be supported by up to 9 grapples simultaneously. "
Microbivores: Artificial Mechanical Phagocytes using Digest using Digest and Discharge Protocol
sunday closet cleaners group presents:
Heres a new one on me ..... the iron and p.aeruginosa connection.....
It has been reported that lactoferrin can cause
deprivation of iron, thus inhibition of biofilm formation in Pseudomonas aeruginosa[/size]. We have observed that biofilm
formation can be blocked using iron chelators such as lactoferrin, EDTA(ethylenediaminetetraacetic acid), and EDDS
(ethylenediaminedisuccinic acid).
Project Leaders:
Janice D. Thomas and Jeffrey H. Toney
Department of Chemistry and Biochemistry
Montclair State University
Montclair, NJ 07043
The shuttle DNA vector pSP3 was constructed to generate mutations by DNA insertion. This construct can replicate in E. coli and in Xylella fastidiosa (Xf). If a DNA fragment containing part of the Xf rpfA gene encoding for aconitase is cloned into pSP3, specific integration of this construct into the rpfA gene will be induced. Previous results with the Xf xpsD gene, using a pSP3(xpsD600) construct, indicate that this vector is useful in generating gene disruption by homologous recombination. We are currently investigating the potential role of the rpfA gene in biofilm production using this gene
disruption technique.
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subset: commoncrawl


text:
Sympathomimetics (Direct, Mixed-Acting)/Guanethidine Interactions
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
Medical warning:
Moderate. These medicines may cause some risk when taken together. Contact your healthcare professional (e.g. doctor or pharmacist) for more information.
How the interaction occurs:
When these two medicines are taken together, your body may not process guanethidine properly.
What might happen:
The beneficial effects of guanethidine may decrease and cause an increase in your blood pressure.
What you should do about this interaction:
Contact your healthcare professionals (e.g. doctor or pharmacist) about taking these two medicines together. They may already be aware of this interaction and may be monitoring you for it. If you experience headache, dizziness, or blurred vision, contact your doctor. Your dose of guanethidine may need adjusting. Do not start, stop, or change the dosage of any medicine before checking with them first.
- 1.Laurence DR, Nagle RE. The effects of bretylium and guanethidine on the pressor responses to noradrenaline and angiotensin. Br J Pharmacol 1963; 21:403-13.
- 2.Muelheims GH, Entrup RW, Paiewonsky D, Mierzwiak DS. Increased sensitivity of the heart to catecholamine-induced arrhythmias following guanethidine. Clin Pharmacol Ther 1965 Nov-Dec;6(6):757-62.
- 3.Gulati OD, Dave BT, Gokhale SD, Shah KM. Antagonism of adrenergic neuron blockade in hypertensive subjects. Clin Pharmacol Ther 1966 Jul-Aug; 7(4):510-4.
- 4.Sneddon JM, Turner P. The interactions of local guanethidine and sympathomimetic amines in the human eye. Arch Ophthalmol 1969 May; 81(5):622-7.
- 5.Spiers AS, Calne DB. Action of dopamine on the human iris. Br Med J 1969 Nov;4(679):333-5.
- 6.Misage JR, McDonald RH Jr. Antagonism of hypotensive action of bethanidine by "common cold" remedy. Br Med J 1970 Nov 7;4(731):347.
- 7.Ober KF, Wang RI. Drug interactions with guanethidine. Clin Pharmacol Ther 1973 Mar-Apr;14(2):190-5.
- 8.Cooper B. "Neo-synephrine" (10%) eye drops. Med J Aust 1968 Aug 31; 55(2):420.


text:
China has made big strides in liberalizing its currency over the last few years and now it is taking steps to facilitate cross-border sweeps of the renminbi, a development that will make life easier for treasuries that operate in China.
Recently, the People's Bank of China (PBOC), the central bank, said that it will allow companies to sweep cash offshore.
"The implementation of this movement of funds is conducted through an intercompany loan," said Joe Ng, Asia Pacific head of Renminbi payments product management for Global Transaction Banking at Deutsche Bank.
Corporate treasuries often sweep funds out of local business units' bank accounts to regional treasury centers to gain liquidity and transparency and to make short-term investing more efficient. Previously, companies could move renminbi out of China to regional treasury centers by paying dividends, but that approach could trigger withholding taxes.
The PBOC's announcement about cross-border sweeping followed a pilot program that began in December 2012. The PBOC is currently operating a pilot program for foreign-currency netting in a few Chinese cities.
The PBOC has yet to release details on cross-border sweeping, Ng said. "We are still waiting for clarity about how much you can move, what the timing is, and the operating procedures around these arrangements," he said.
Citibank responded to the PBOC's move by launching a product in September that automates renminbi cross-border sweeping. Rachel Wang, treasury advisor for Citi Treasury and Trade Solutions in Shanghai, said the solution "gives our clients more convenience to leverage this new PBOC announcement."
"Because of the FX restrictions, trapped cash in China used to be a big challenge for multinationals' liquidity management," Wang said. With the advent of sweeping, "the trapped cash problem can be solved to a great extent," she said.
"Most of the interest comes from multinationals," Wang said. For global treasury operations, "China was a missing piece. For multinationals, it's good to have China being part of the global family, to start netting, [pay-on-behalf-of, receive-on-behalf-of structures] or cash pooling to their global or regional treasury centers," she said.
Deutsche Bank's Ng also cites "very strong interest" among multinationals in being able to move cash cross-border.
"If we think about the global treasury management strategy of multinationals, previously what they could do in China was mostly concentrate on current account items, or what we call trade settlement," said Ng, pictured at left. "The use of renminbi for trade settlement in itself can create value. But the movement of these intercompany loans will help increase the flexibility of multinational companies to manage their renminbi positions on a global basis, essentially using the currency for treasury management. It will also enable the repatriation of funds from China through the intercompany loans."
He added: "We see this as a tipping point for more use of renminbi for both trade and investment."
The internationalization of the renminbi involves more cross-border use of the currency, Ng said, adding that offshore renminbi currently makes up less than 1% of the currency's global total, with 99% on shore.
Ng pointed out that SWIFT's research indicates that while China constitutes nearly 10% of the world's GDP, only about 1% of global foreign exchange activity occurs in renminbi. And while more than 30% of Japan's trade is transacted in yen and 60% of the eurozone's imports and exports are denominated in euros, 16% of China's imports and exports are denominated in renminbi, he said. "So from a transactional point of view, there is room for the renminbi to rise."
The renminbi, also known as RMB, has definitely come a long way since China started its liberalization in 2009. In September, the Bank for International Settlements' triennial survey of global foreign exchange trading showed the renminbi for the first time ranked as one of the world's ten most frequently traded currencies, rising to ninth place, up from number 17 three years ago.
"That shows you how the rule changes have just made it easy for companies all over the world to deal with the RMB," said Alfred Nader, vice president of corporate strategy and development at Western Union Business Solutions.
Still, an HSBC survey released this summer found that just 9% of U.S. companies doing business in China paid with renminbi. But HSBC cited SWIFT data showing that 47 countries now make more than 10% of their payments to China and Hong Kong in renminbi.
Michael McDonough, senior vice president and head of product, global trade and finance receivables in North America at HSBC Bank USA, N.A., said companies aren't yet as familiar with using the Chinese currency as they may be with other leading currencies. According to the HSBC survey, 67% of U.S. companies that weren't using the renminbi said it was because they weren't aware of the benefits or hadn't fully considered it, while 40% cited a preference for using dollars or an interest in avoiding forex fluctuations. Just 26% had concerns about regulations.
"What you've got here is a situation where there's a need to educate the market," McDonough said. "What companies are going to find is that dealing in the RMB will prove to be largely akin to other FX transactions that companies have gotten their arms around."
McDonough cited the advantages that paying in the Chinese currency can provide, such as better pricing. And McDonough noted that financial institutions outside of China are "increasingly able to provide renminbi financing to exporting clients in their particular region."
Western Union's Nader also cited the advantages of paying in renminbi (RMB). "If they negotiate in the RMB, companies get upwards of 5% off of their invoice," said Nader, pictured at left. "And they can get more attractive payment terms. The Chinese have been hesitant to offer payment terms longer than 30 days because of the U.S. dollar weakening. But if they're being paid in RMB, you're seeing companies being able to hold onto their money longer."
Nader said that U.S. companies' use of the renminbi could gather momentum if some of the big U.S. importers of Chinese manufactured goods make the switch. "If companies like Wal-Mart and Target start to pay their Chinese exporters in the RMB, you're going to see a huge domino effect," he said. "All the smaller folks are going to have their suppliers asking to be paid in RMB."
Read the October Special Report on SEPA.
Ready, Set, SEPA
Corporate Perspective on SEPA
Rupee's Slide Ruffles Outsourcing Customers
To Boldly Go
Standardize, Re-engineer, Rationalize
SEPA: The Gateway to New Value-Added Services


text:
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We are consumers and customers like yourself and we understand that your satisfaction comes first. For products purchased directly on our website and not Amazon, we stand by our products, which is why we offer a 1 year hassle-free replacement warranty on all of our Standard Kits and bulbs, and 3 years on our Premium CANBus Ballasts. We take pride in the products and service we provide. If you are not 100% satisfied with our products or our service in the first 30 days, we will refund 100% of your purchase price*.
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Company says drug-dispensing machines not especially vulnerable
JANESVILLE—Despite a recent case involving a Janesville doctor accused of using a medication-dispensing machine to obtain painkillers, a spokeswoman for the company that makes the machine said they are no more susceptible to fraud than pharmacies.
When Dr. Richard N. Barney wanted to get painkillers, he wrote out prescriptions in the names of patients and picked up the drugs for himself, according to an indictment filed in federal court Wednesday.
He didn't have to go to a pharmacist to pick up those drugs, however. He needed only visit the InstyMeds machine at Beloit Memorial Hospital where, authorities said, the automated medication dispenser filled Barney's fake prescriptions.
Barney went through that process 15 times, according to the indictment, on a few occasions visiting the machine three times in one week.
Mercy Health System officials became aware of the criminal investigation Wednesday, Vice President Barb Bortner said. Barney was on personal leave as of Thursday, Bortner said.
The case would appear to expose a vulnerability of the vending machine-style dispensers.
But a company spokeswoman and one pharmacy expert said Thursday the same thing could have happened at a pharmacy counter.
"A doctor could easily write themselves a prescription and go to a pharmacy," InstyMeds marketing manager Emily Caroon said. "It's really no different."
The machines carry medications people need quickly—antibiotics, inhalers, antihistamines and, yes, painkillers—and can be available 24 hours a day, Caroon said.
They also give hospitals a relatively simple way to provide commonly prescribed medications without opening a whole pharmacy counter, she said. That's particularly useful in small towns.
"In some of our locations, they don't have a pharmacy within 50 miles," Caroon said. "To have that there versus the patient trying to get to a pharmacy, that's huge for some people."
InstyMeds work as if an ATM was crossed with a soda vending machine, essentially.
When a doctor prescribes a medication, the patient has the option to pick it up at an InstyMeds location inside the hospital.
The doctor enters a prescription into InstyMeds' computer system and gives the patient a voucher with a unique code. Patients then enter their code into the machine's touch-screen interface and pay with credit cards or cash.
That's when InstyMeds goes to work, selecting one of the pre-filled bottles inside that matches the strength and number of pills prescribed by the doctor—verifying with barcodes to ensure it's picked the right bottle.
After a few minutes, InstyMeds says, the medication pops out and the patient can pick it up.
The Minneapolis-based company has about 200 machines in hospitals around the country, Caroon said, including 53 in Wisconsin and four in Rock County.
Ed Elder, director of the Zeeh Pharmaceutical Experiment Station at UW-Madison, says machines such as InstyMeds reduce the busy work of counting pills and let pharmacists be more effective.
Still, the system is not without its risks—perhaps, if he went to a pharmacist, someone would notice a doctor picking up three Percocet prescriptions in his patients' names each week, for instance.
Those pharmacies can be vulnerable to fraud too, Caroon pointed out.
A doctor could go to three pharmacies scattered around town to fill those prescriptions, and the pharmacists there wouldn't know, Caroon said.
The automated machines would at least have an electronic record through its credit card readers showing who was paying for the medications, she said.
By themselves, Elder said, the machines do not make fraud more likely. If they do contribute to fraud, it will be because of the people using them, he said.
"I don't know if the machine itself is going to contribute to that or if it's more the lack of controls in the specific setting in which it's used," Elder said.
And when it's a doctor who decides to fraudulently prescribe medications, Elder said, there aren't many checks available to keep him or her from getting those drugs.
"Can you blame the machine for the failure of the system when it's just one part?" Elder said.


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Possible fairgrounds move sparks passionate speeches
JANESVILLE--Passionate pleas from long-time fair supporters over moving the county fair from Janesville to Evansville filled a sticky sale arena Monday night at the Rock County 4-H Fairgrounds.
Moving from a central location to a corner of the county was a top concern expressed. Supporters of a move said no other community has offered a site while Janesville leaders have lacked support in keeping the event in the city.
More than a dozen people from the Rock County Fair Board and Association spoke at the county's Agriculture and Extension Committee meeting on a proposal to move the fair to a site on the east side of Evansville.
The county, which owns the fairgrounds, is in wait-and-see mode on the fair board, which runs the fair, ag committee Chairman Rich Bostwick said.
"It seems, as a group, they don't have a unified vision at this point," he said of the fair board and association, which elects the fair board. "I just heard varying opinions that made me think they have to work things out more before they come up with some proposal."
The fair board will continue discussions at its monthly meetings, fair board President Rob McConnell said. Many details have not been discussed with the non-profit group proposing the Evansville site.
That group, Southern Wisconsin Agricultural Group, is working on a business plan and hopes to raise $16 million to $20 million to build a regional agricultural events and education center on more than 200 acres it owns in Evansville.
"There's a ton of negotiation to go through. It's still in a concept phase," said McConnell, who also is a SWAG board member. He said he would not cast fair board votes related to SWAG.
County, fair and SWAG officials say they have not discussed costs. The city of Evansville approved paying for a traffic analysis study last month, when a SWAG member also said it could be looking for $4 million from the city through the existing TIF district, according to meeting minutes.�
Here's what some residents said:
--Les Arnold of the Rock County Pork Producers said his organization and the money it gives back to the community would suffer if the fairgrounds were not centrally located. He said his group was not against a new fairgrounds, but having it in Evansville would force some residents to make 60-mile round trips and be at the mercy of a private entity.
-- Fair board member Dean Peterson would love to see the fair stay in Janesville, but he said because of a lack of leadership in the county to find a new site, he would probably vote for the Evansville site.
"We need a new facility very, very badly," he said.
Peterson cited the economic impact Jefferson County realizes by supporting its fairgrounds.
"I think our county board is really short-sighted" by saying they can't do anything to build a new facility, he said.
--Cathy Wendtland of Clinton voiced concerns about making teens travel across the county, which could result in them not making nightly curfews.
"That's a long commute for some of these kids who are just starting to drive," she said.
She also worried "a lot" of 4-H clubs would dissolve because people wouldn't be able to afford to travel.
--Fair board member Bob Risseeuw said SWAG presents a "tremendous opportunity," but a lot of unanswered questions weigh on him. If a move was to take place in the future, things need to be established so there are no guessing games.
--Fair board member Scott Davis said he appreciates SWAG's concept, but he would not vote to move the fair because it needs a central location.
"I think the risk of losing this facility and not having a place to go is huge," he said.
--Fair board member Craig O'Leary said a new venue is needed, no other community has stepped forward, and they have never "heard a peep" from Janesville officials about the economic benefit the fair provides the city.
Instead, the city tickets parked cars.
"We're being harassed by the city, we're not welcome at all," he said.


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QtIPy is a simple GUI-based automator for IPython notebooks. It allows you to attach triggers to files, folders, or timers to automatically run notebooks. IPython notebooks are great for interactively working through analysis problems, so why would you want to automatically run them? To get a record of how you ran your analysis! By running a notebook through QtIPy you get the output, figures, and a step by step log of how the analysis was performed all in the same folder.
Wunderbar is a program which is able to identify mislabeled samples in genotype data when a few extra independent genotypes are available ("genetic barcoding"). Wunderbar calculates the likelihood that genotype mismatches have occurred by chance. It is capable of reliable and sensitive detection of sample mismatches and swaps even in the presence of numerous genotyping errors and in the presence of linkage disequibrilium between the individual genotypes. It only requires a few SNPs to work well.
Pathomx is a workflow-based tool for the analysis of metabolomic and other omics datasets. It is interactive, visual, extensible, intelligent, and free for any use. It lets you dynamically build analysis workflows using the interactive editor. Drag and drop connections between plugin tools to create a complete workflow through which to run your analysis. Data can be loaded and processed automatically, and new approaches tested simply by connecting tools.
Fqutils provides a basic set of bioinformatics command line tools for working with sequence data in FASTQ format. It complements Greg Hannon's fine Fastx Toolkit suite. One characteristic of Fqutils is that it correctly handles the full FASTQ format as described by the published standard, which specifically allows multi-line sequence and quality score information per record. Fqutils is intended to be useful as part of the early portions of post-sequencing pipelines and quality assessment processes.
Visualization of Protein Ligand Graphs (VPLG) uses a graph-based model to describe the structure of proteins on the super-secondary structure level. A protein-ligand graph is computed from the atomic coordinates in a PDB file and the secondary structure assignments of the DSSP algorithm. In this graph, vertices represent secondary structure elements (SSEs, usually alpha helices and beta strands) or ligand molecules, while the edges model contacts and relative orientations between them. The graphs can be visualized, written to a database, and saved in a text-based file format.
A camera app for Android.
A command-line network analysis workbench.


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National Level Resources
"Bringing Learning to Life" - Learn and Serve America's video promoting service-learning is available through their National Service-Learning Clearinghouse.
State Level Resources
Service-Learning Brochure – A brief overview of service-learning basics.
Service-Learning 101 – A detailed power point intended to introduce the audience to service-learning - great for trainings and professional development.
MSDE Service-Learning Guidelines – A brief description of the guidelines that service-learning projects in Maryland are subject to.
Service-Learning Professional Development Institute 2005 Plenary Power Point – This power point introduces and highlights key information in the MSDE Service-Learning Guidelines. Click here for the power point version.
Preparation, Action, Reflection – A brief overview of the cornerstone of implementing effective, meaningful service-learning projects.
Middle School Service-Learning Instructional Framework – This contains several helpful documents aimed at implementing effective service-learning in the middle school. It also includes a variety of projects and ideas to get you and your students started.
Training Toolbox: A Guide to Service-Learning Training (Part I) – This contains the training guides for service-learning professional development with differentiation for time sensitive workshops.
Training Toolbox: Appendix (Part II) – This contains a variety of instructional materials, worksheets, and activities meant for classroom and professional development use! Excellent materials for preparing students for service-learning, including "The Baby Story, "The World in Pretzels", and "Hunger Awareness Quiz".
Local School System Resources


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Walworth County Board approves park, budget
ELKHORN—Walworth County will have a new park for its residents and visitors.
The Walworth County Board approved the purchase of 190.5 acres off Sheridan Springs Road on Tuesday night.
The county will pay $1.91 million for White River Park and then be reimbursed by a Wisconsin Department of Natural Resources grant for half, or $955,000.
Voting against the acquisition of the land were board members Carl Redenius and Richard Brandl.
Developing the land for hunting, trails and other recreational activities could cost more than expected, Redenius said. Redenius also claims the county is paying twice what the land is worth.
Nancy Russell said she was happy with the board's approval.
"This is by far the best piece of property we could find in the city and is well worth the money," Russell said.�
She said this is the first park the county has purchased in ten years and hopes to have it open by the summer 2014.
The board also unanimously approved the 2014 county budget of about $138 million.
It is the second budget to pass with a tax levy that does not exceed the amount allocated the previous year. The 2014 tax levy is $2,003 less than 2013.�
At the October preliminary hearing the county board proposed a budget with a tax levy $80,000 less than in 2013. After further inspection of the preliminary budget the county board realized it needed to account for a $278,516 increase in workers compensation premiums. The tax levy will be used to pay $78,516 of that increase.
The tax rate increase of 3.37 percent from $4.56 per $1,000 of assessed value to $4.72 per $1,000 is due to a decrease in the county's property value, said Nicki Andersen, deputy county administrator.
The budget allows the county to hire five full-time employees for various departments.
As in previous years, the majority of the county's expenses and the majority of the tax levy will go toward the sheriff's office and Health and Human Services.


text:
The largest global banks cut the shortfall in the reserves they'll need to meet Basel capital rules by 82.9 billion euros ($112 billion) in the second half of 2012, leaving a gap of 115 billion euros.
"Shortfalls in the risk-based capital of large internationally active banks continue to shrink," the Basel Committee on Banking Supervision said in a statement on its website. The capital gap narrowed by about 42 percent at the end of 2012 compared with the middle of last year, the group said. The requirements, known as Basel III, are scheduled to fully phase in by 2019.
Lenders also need to do further work to meet a planned binding limit on bank indebtedness, known as a leverage ratio, the Basel group said. A quarter of large global banks failed to meet the standard, it said.
Global regulators have clashed with lenders over the severity of capital, indebtedness and liquidity rules, which were set out in 2010 as part of an overhaul of banking regulation to avoid a repeat of the financial crisis that followed the collapse of Lehman Brothers Holdings Inc. The Basel III measures will more than triple the core capital that lenders must hold to at least 7 percent of their assets, weighted for risk.
The biggest lenders in Europe account for 70.4 billion euros of the capital shortfall at the end of last year identified by the Basel committee, the European Banking Authority said in a separate statement today. They boosted their capital levels by 29 billion euros from June 2012, the EBA said.
Banks can plug gaps in capital by either boosting their reserves or by reducing their assets weighted for risk.
Both the EU and the U.S. missed a January 2013 deadline to begin phasing in the Basel standards on capital, and have said they will start the process from next year.
A sample of 222 banks surveyed by the Basel committee, including 101 large international lenders, had a combined shortfall of 563 billion euros in the easy-to-sell assets needed to meet one of the Basel liquidity rules, the group said. The liquidity coverage ratio is also set to fully apply from 2019.
The sample of banks also had a 2 trillion euro shortfall in the stable funding needed to meet a separate Basel requirement for banks to back long-term lending with funds that are unlikely to dry up in a crisis. This measure, known as a net-stable funding ratio, is under review by the Basel committee, and is scheduled to become a binding requirement on Jan. 1, 2018.
The Basel group defines large global banks as those with more than 3 billion euros in Tier 1 capital and which are internationally active.
Bloomberg News
The U.S., U.K., Sweden and Switzerland are among nations that have promised to set tougher rules for their banks than required by Basel.
Bloomberg News


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Theories - Origin of Life
Discussion of everything related to the Theory of Evolution.
Moderator: BioTeam
Re: Theories - Origin of Life
Really now you simply need do better than that.
"New species created in Lab"
Hasn't the obvious struck you?
An outside agency was required for whatever the result was.
That is precisely the nub of my argument relating to species formation.
Don't you realise you are making my point for me.
I of course assume you are referring to the "Long-term evolution of Pseudomonas in the human host" article. Even the article does not make the claim you are attributing to it. So please at least report these experiments without any philosophical spin to buttress your arguments.
You keep going on about my beliefs, so let's put you out of your obvious frustation.
Now you have stated you couldn't not respond to my enquires because you did not understand theory enough to be able to explain it.
So you don't really understand what you actually believe.
However I understand exactly what I believe.
I believe in the veracity of the Scientific method.
Here is my understanding of this method and I am very clear about it.
The essential elements of a scientific method are :-
Operation - Some action done to the system being investigated
Observation - What happens when the operation is done to the system
Model - A fact, hypothesis, theory, or the phenomenon itself at a certain moment
Utility Function - A measure of the usefulness of the model to explain, predict, and control.
One of the elements of any scientific utility function is the refutability of the model. Another is its simplicity, on the Principle of Parsimony also known as Occam's razor.
I assume you include your own mouth in this analysis.
I understand your point completely. Your emotions are coming over in a very obvious manner.
I am still waiting. Please keep trying.
Re: Theories - Origin of Life
Sorry not to have pushed further, but I had to recover from surgery and then had to get back to work. But I will once again try it.
The whole point of the bad design argument is not that bad design is evidence of randomness but that it is evidence of a complete lack of planning, foresight and generally what we call design in nature. See the ancester of bears had a thumb, but they lost it. Then came the Panda and a thumb would have been useful, and instead of taking the old very good design of a thumb, something else had to evolve. But there was no coming back, it had to come from something that was still there in the panda's genetic toolbox.
The argument is that if there was design, the reliance on necessity and on what is there, instead of what is available in the life's toolbox in general is proof that there is no overarching design, plan(ner) or anything that can select from what is available at large. And the selection is limited to what is genetically available. That makes sense in the framework of evolutionnary biology, this is stupid if your hypothesize that there is a designer behind things.
And I see that you are using the old Occam's razor saw a bit down thread. You know the "a designer is a simpler explanation that random accumulation of unlikely event yada yada yada..." kind of argument. Would you care to tell us where the designer comes from? because if there is one, it must come from somewhere, no? And we now have a very interesting recursive loop in the making, that does not appear to be any more probable than random accumulation of rare events followed by selection.
Science has proof without any certainty. Creationists have certainty without
any proof. (Ashley Montague)
Wrong article, It's the one about the lizards.
It describes a new species of parthenogenic lizards created by hybridizing two related lizards. This is proof of concept for these lizards producing a plethora of related species, both parthenogenic and sexaully reproducing.
Yes I am Biased. I know that and keep it constantly in mind and pay careful attention to how it feels.
Are you claiming a lack of bias?
So you are telling me that the fact that species have never been seen diverging and the fact that species have now been seen diverging are both arguements for intelligent design?
Re: Theories - Origin of Life
I take it then you mean this one
http://arstechnica.com/science/news/201 ... he-lab.ars
It describes a new species of parthenogenic lizards created by hybridizing two related lizards.
Here is a clue for you
This article is based on the paper entitled.
"Laboratory synthesis of an independently reproducing vertebrate species." By Aracely A. Lutes, Diana P. Baumann, William B. Neaves, and Peter Baumann. Proceedings of the National Academy of Sciences, Vol. 108. No. 18, May 3, 2011.
Now I could go into the details of the paper, but the obvious stands out so clearly that I don't need to dig into it, and here is why.
Hybridization is the cross breeding of related organisms within a given species.
It also involves the input of an outside agency (i.e. the researcher) which is what this research experiment is all about.
Has a new species been created?
Let me refer you back to how this forum defines species.
(1)The lowest taxonomic rank, and the most basic unit or category of biological classification.
(2) An individual belonging to a group of organisms (or the entire group itself) having common characteristics and (usually) are capable of mating with one another.
The sloppy use of this term species can lead to any amount of slight of hand conclusions, if that is where one wishes to go.
Please read the abstract I have provided here
http://www.pnas.org/content/early/2011/ ... 8.abstract
Go to the Materials and Methods of the paper to understand the degree of outside input that was required to arrive at their destination
You notice I use the word destination. Why?
Because there was a purpose to this experiment.
Since when has random mutations had a purpose.
Natural selection even, does not come into play.
Artificial selection however does.
You are trying to use artificial input and artificial selection to prove randomness.
What sort of logic is this?
Of course an outside agency can modify the genetic material of an organism to create a different species. (if of course that agency has the capacity.)
That is my point. It requires an outside agency.
I am arguing for design in biology. I don't need to preface the word with adjectives, be it (un)intelligent, apparent, good bad or whatever.
The biological algorithms we see operating in the cell fit perfectly within the requirements of analysis by the scientific method.
And algorithms by their very nature are not the product of natural law. They use natural laws towards a specific function or purpose.
Now if you can demonstrate any of the evolutionary models to fit into the scientific method of analysis, then you have a genuine scientific theory.
If you cannot then you have, at best a hypothesis that is not standing the test of the scientific method.
Now in fairness you have declared a bias toward this hypothesis of whatever model and
I don't have a problem with that and do sincerely respect your viewpoint.
All I ask is that you do not present it as science, because then I have to take issue.
You ask
Are you claiming a lack of bias?
We all could be guilty of having a bias.
What sticking to the scientific method does in any analysis, is to remove any bias.
Now if you can show me where I have strayed outside the scientific method in any analysis
I have presented I will correct it.
I have no problem in being corrected. I have found through experience, that being corrected is one of the best forms of learning.
Your definition of hybrid is wrong. To be a hybrid the parents must be different species. (again we have the species definition to contend with).
and it does happen in nature. The new species isn't the same as either of the parent species and is self replicating.
If it's not a new species created by means common in nature, what is it?
Obviously, this is kind of a back door way to create a new species but it is a way that can be accomplished in a short time and is therefore amenable to recreation in the lab.
As I said it's a proof of concept showing that this group of related lizards could have arisen by simple hybridization.
As for how selection takes place, natural, sexual,domestication, they all work to shape the gene pool. Arguments about which takes precidence I think are silly semantics. Selection is Selection.
Could be guilty of bias? No No No. Always bias, all day every day.
There are still a huge number of people who believe President Obama was not born in Hawaii despite the documentary proof they asked for. As soon as you think you are unbiased then bias has you in it's insideous grasp.
The hallmark of bias is the inability to take in information that would endanger the comfortable world view that creates the bias. You litterally have to make an effort to see the evidence.
Re: Theories - Origin of Life
Sorry to hear about your surgery, I do hope you are on a good trajectory back to full health.
I understand the argument you are making but it lacks coherence.
Let me explain
You appear to completely ignore any evidence that does not fit your ideas.
The analogy of the "Panda's thumb" is sheer nonsense and although being refuted is still being perpetuated as evidence of as you now put it of a complete lack of planning, foresight and generally what we call design in nature.
Now really please read the paper if you haven't taken the trouble already.
You will find the paper in Nature (peer reviewed of course) here
http://www.nature.com/nature/journal/v3 ... 309a0.html
(my emphasis)"
The panda has specific needs (stripping bark off bamboo for some 12 hours a day is not an activity normally associated with other mammals)
If the panda evolved as you describe ( I will come back to this later) of what better use would the ordinary thumb be over the 'pseudo-thumb'. Can you explain?
The environment, the diet and the eating habit of the panda required forward planning and foresight as you say and that is what we see.
But it is not just this digit that is evidence of forward planning for particular diet and eating habits.
Here is a description of the digestive system you will find here
http://factsanddetails.com/china.php?it ... ubcatid=68
No forward planning eh. It's all randomness is it?
Now let me come on to this idea of common decent.
You say
This is just sheer speculation and you know it.
If I were to ask you ( but I wont because you not not be able to give me one) who or what was this ancestor of the bears, you would not be able to give one.
Because there is no evidence for this.
This idea of a common ancestor is based on a Doctrine that has run it's course and is now being rejected by some of the most prominent biologists.
Among such ones as Carl Woese and many many others there is Eugene Koonin of the National Center for Biotechnology Information, National Library of Medicine, and National Institutes of Health
Koonin is widely regarded and is certainly at the center of the scientific establishment.
In 2007 he presented a paper which is online here
It is entitled
"The Biological Big Bang model for the major transitions in evolution."
May I urge you to read it please and not continue to be taken in by this myth of common decent.
Only the priesthood of Darwinian doctrine continue with this myth.
Now let me respond to your final little bit of rhetoric
Do you accept Kepler's Laws of motion? – Of course you do
Do you accept Newton's Laws on gravity --- Of course you do
Do you accept Maxwell's Laws on Electromagnetism – Of course you do
Did Kepler or Newton or Maxwell make those laws? Do tell please -- who?
But you accept them all without knowing don't you?
So instead of all your
let us make a deal
You tell me who made those Laws and I will tell you who designed the cell.
Your point about the adaptation of the panda's thumb is irrelevant. It does not prove design, just adaptation. Interestingly I would point that the carnivorous and wasteful digestive system of said animal is once again a good argument for its link with other bears (who are all carnivorous). The adaptation of its digestive flora is once again irrelevant to the point, it does adapt. And frigging quickly. Observing variation of any individual digestive flora over time (and even more so if its diet is modified) is easy. Understanding waht happens is another story, though...
As for the laws of physics, nobody designed them. They are the consequence of the interaction whatever constituted the primordial soup of the Big Bang.
But who designed your designer? I do not give a **** who or what it is, but if it has the power to interact with our world, it comes from somewhere. Yet we know that it cannot come from nothing as design is essantial to anything. So who designed your designer?
See that is why it is dangerous to play with a razor, you can hurt yourself.
Science has proof without any certainty. Creationists have certainty without
any proof. (Ashley Montague)
Re: Theories - Origin of Life
Since you are having trouble with a definition of species why don't you sort out in your own mind what constitutes "a species" and then we can continue our discussion.
Oh dear
Did you really think this one through?
Is this supposed to be an explanation based on science?
Your confusion in the mixing of two concepts from two different hypothesis reveals more about what you don't understand, than about what you do understand.
The primordial soup is the start point from which Darwin formulated his Origin of species hypothesis. Somehow life came into being from some chemicals.
No one has even figured out what this so called soup consisted of. Scientists have only been able to speculate as to what it may have consisted of.
The most fundamental law in biology is that life comes only from another pre-existing life.
Louis Pasteur clarified this law of Biogenesis about 150 years ago. I take it you did learn about this at school.( Incidently, Pasteur and Darwin were contemporaries.)
Funny that eh ! Darwin hypothesising that life started from a chemical soup and Pasteur showing through science that it couldn't.
But hey why let science stand in the way of a good story.
The Big Bang hypothesis starts with a mathematical concept called Singularity.
Singularity has no physical existence.
Monsignor Georges Lemaître a Belgian Catholic priest proposed the Big Bang hypothesis.
Of course it had a few rather basic problems so in 1980 Alan Guth bolted on his hypothesis which we know as Inflation theory to try and make some sense of the Big Bang but created even more problems.
By the way George Lemaitre also believed that the Virgin Mary was assumed body and soul into heaven at her death.
Do you now understand the difference between these two theories? Good
So now lets go a little further
Now you should at least know this one.
The most fundamental law in physics is the law of the conservation of energy.
In the natural world neither matter nor energy can be created or destroyed.
Therefore either matter and energy has had no beginning (i.e. it has always existed, the concept of infinity)
it was brought into existence as a consequence of an action outside the physical world.
Since infinity is simply a mathematical construct and has no physical existence the latter must apply.
That is why our Catholic priest thought up this hypothesis to explain how his god would have have created the universe.
So your answer is both scientifically wrong and religiously based.
Your confusion reveals not your science but your religion.
And all religions have dogmas.
So would you like to try again
Once you have absorbed this little lesson we can continue with our science class.
Re: Theories - Origin of Life
I am able to get back to the forum for the weekend and
Yes I accept your deal
to create, fashion, execute, or construct according to plan or purpose
Examples of designers in the natural world
Birds – constructing a nest
Ants – constructing a anthill
Examples of religion's chief designers (supposedly)
Christendom's Triune god
Islam's Allah
Hindu's Vishnu
Egyptian's Amon
Evolution's Random mutation
Etc, etc, etc,
Examples of human designers
Isambard Kingdom Brunell --- bridges
Isaac Newton --- telescope
Robert Oppenheimer --- atomic bomb
Etc, etc, etc.
Now Regarding the designer of the cell.
I am not able to define the designer, any more than I can define the maker of the natural laws.
Neither can you or anyone else.
That is why I was able to confidentially offer the deal canalon.
However what I find amusing are the arrogant assumptions some have who claim they can, only to find that when their claims are put to the test and found wanting, they have to try and change the debate to one of belief or religion.
Science does not need to define the designer of anything to acknowledge the fact that design is there.
Religions however by their nature have to, in order to attract believers.
However you can as indeed I can define an understanding of species.
There is enough information around to be able to do this.
So do tell please what is it? I have already given you my understanding.
WRONG, If you posit a designer it is incumbant on you to define as much as you can and attempt to prove/ disprove it.
"I believe in a designer that can design the cell." doesn't cut it.
and they say survival of the fittest is a tautology.
I am only interested in practical theories. Does your designer currently do anything? Will any more designs be forthcoming? Does your designer have any interest in helping or hurting me?
If your designer is beyond the reach of scientific investigation then they might as well be in a different universe and anything said about them is pointless speculation (Phylosophy).
The designer positted by modern biology is well defined. Mostly (if not completely) random changes in the genetic material of preexisting organisms ( or almost living chemical systems capable of some crude form of replication) provide variation in the population. Selection (natural, sexual, domestication) removes variations that don't fit in an available niche. The remaining organisms reproduce. Repeat, repeat ,repeat.
Things you wouldn't expect to see. Perfection, this process is a little messy. Completely new designs with no previous history. Virgin birth
(Spontaneous generation)
Notice I don't mention your arguement. Complexity is not evidence against this process. Life doesn't violate any thermodynamic laws.
Organic molecules are perfectly capable of creating bizarrely complex systems without intelligent input.
If you find a watch on the beach it is perfectly logical to look around for the owner/maker. If however you find a crab on the beach there is no reason to look for it's creator. It's pretty likely other crabs were involved.
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Top 10 electronics business deals of 2012
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Here are 10 of the most significant technology mergers and acquisitions of 2012.
LONDON -- Despite a rocky global economy in 2012, consumer spending on tablet computers and smart phones remained strong as the era of the personal computer fades. These realities helped shape the electronics landscape this year, creating winners and losers in the semiconductor industry and a considerable number of significant mergers and acquisitions.
One of the most intriguing deals, the sale of processor IP licensor MIPS Technologies Inc. (Sunnyvale, Calif.) is still playing out. In November, graphics IP specialist Imagination Technologies it had agreed to buy MIPS' operating business for $60 million while another U.K. company, ARM, would lead a consortium called Bridge Crossing. that would acquire rights to the MIPS portfolio of patents. Bridge Crossing would pay $350 million in cash to purchase the rights to the MIPS portfolio, of which ARM will contribute $167.5 million (see ARM and Imagination divide up MIPS)
Two weeks later, however, Ceva Inc. (Mountain View, Calif.) sought to trump Imagination's offer for MIPS by bidding $75 million. MIPS shareholders are undoubtedly hoping Imagination or another bidder will respond with an even better offer.
There were other deals this year in the mixed-signal and RF market segments, including GPS and wireless chip company U-blox acquiring chip startup Cognovo for $16.5 million along with 4M Wireless for $9 million, both for their expertise in 3GPP LTE technology (see U-box buys Cognovo and 4M Wireless).
Here's the list:
The semiconductor mergers and acquisitions described below and on the following pages represent some of the key technology deals of 2012. They also illustrate the constant churn and reshaping of the global electronics industry. (Please note they're not ranked or ordered; all are considered significant.)
Deal: Apple Bites Anobit
Early in 2012, Apple announced its acquisition of flash memory controller startup Anobit Technologies (Herzeliya, Israel) for about $390 million. Anobit represented a catch for Apple because the Israeli company developed NAND flash memory controller technology that improves the apparent endurance of flash memory the number of reads and writes it can perform.
The Anobit deal underscores an industry trend as all-powerful Apple pulls in key aspects of its supply chain. Left unanswered for now is whether Apple will in the coming year move to internal chip manufacturing. (see Apple buys Anobit).


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Check out the UrbanScooters.com Marketplace for a HUGE selection of CURRIE ELECTRIC SCOOTERS from across the Internet. Currie scooters and bikes are manufactured under the Schwinn, Mongoose, GT and IZip brand names.
Currie electric scooters and bikes are manufactured by Currie Technologies, Inc. Currie Technologies was founded in 1998 by Richard Mayer and Dr. Malcolm R. Currie, the former chairman and CEO of Hughes Aircraft and Delco Electronics. Currie scooters are sold under several brand names including Schwinn, Mongoose, GT and IZip. Currie electric bicycles are sold under the Currie electric scooter brand, IZip and Mongoose. All Currie Scooters are powered by the "Electro-Drive Propulsion System", a unique drive system that provides superior performance and durability at a reasonable price. The company's objective is to build Currie scooter products that offer cost effective, emissions free alternatives to other forms of transportation.
You'll find a huge Currie Scooter selection in the UrbanScooters.com Marketplace, including exceptional deals on;
• IZip Skate Wheel - Currie Scooter
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• Schwinn S-500 Currie Electric Scooter
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• Schwinn S750 Currie Electric Scooter
• Schwinn Stealth S1000 Currie Scooter


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The Rachel Maddow Show 09/23/16
Cruz abandons principle to make Trump endorsement
Rachel Maddow reports on Senator Ted Cruz's endorsement of Donald Trump for president despite having engaged in an exchange of grievous insults with Trump during the Republican primary. ... more Duration: {{video.duration.momentjs}}
Cruz abandons principle, endorses Trump
TRMS Law School: What if Trump pardons Flynn?
TRMS Law School: How independent is the FBI?
TRMS Law School: Lightning round!
What happens to probe if Mueller is fired?
What is a constitutional crisis?
Former prosecutors offer advice to Trump
Trump admin distinguished by departures
Trump favor for Russia a security risk: WaPo
Democrats due for landslide if momentum holds
Dissenters tempt GOP failure on tax bill
Roy Moore mistaken in Alabama recount claim
Trump clout further eroded by election losses
Alabama Democrats look to 2018 with new hope
GOP seeks excuse for Trump to fire Mueller
Fake comments prompt call for FCC vote delay
Doug Jones built no-holds-barred campaign
Bannon will find someone to blame for loss
Jones campaign leaves Democrats energized
Booker: We cannot allow Roy Moore to serve
Retrieving data...
- Information
Rachel Maddow
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Putin Calls Trump to Thank Him For CIA Tip Thwarting Bomb Plot
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With Rubio & Corker onboard, Trump may get his tax bill
Trump: Not ready to talk about Flynn pardon... yet
Lawrence: Rich get richer in deficit-exploding tax bill
Trump, Republican war against FBI, Mueller probe
Bartlett: Tax bill helps rich, gives 'crumbs' to families
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TRMS Law School: Lightning round!
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The U.S. Commodity Futures Trading Commission (CFTC) is considering a six-month phase-in period to implement new rules for overseas swaps trades, according to two people with knowledge of the deliberations.
Regulators face a Friday deadline to resolve a deadlock over how far to expand the regulator's oversight over trades conducted outside the U.S. by banks including JPMorgan Chase & Co. and Goldman Sachs Group Inc.
CFTC members remain at odds over the regulator's overseas reach, according to the people, who spoke on condition of anonymity because the deliberations are private. The agency has set a July 12 meeting to vote on the rules.
The international reach of Dodd-Frank Act regulations has been one of the most controversial parts of the government's effort to reduce risk and increase transparency in the $633 trillion swaps market. Regulators around the world decided to increase oversight of the market after largely unregulated swaps helped fuel the 2008 credit crisis and led to the collapse of American International Group Inc., a New York-based insurer that booked many of its swaps trades in Europe.
The CFTC's proposed guidelines—which could extend agency oversight to many trades conducted by overseas U.S. banks or subsidiaries—have created a rift with foreign regulators, who say their rules are sufficient for regulating derivatives trades in their jurisdictions.
"Having told us to get our act together—which we are now clearly doing—is the U.S. suggesting that they cannot trust our systems and that only their rules can apply?" Nadia Calvino, the European Commission's deputy-director general for internal market and services, said in a speech last week in Brussels.
The CFTC's proposed guidance was criticized by JPMorgan and other U.S. banks for threatening to put them at a competitive disadvantage when they trade overseas.
Swaps trading has been a major source of revenue for large U.S. banks, and some have conducted roughly half of such trades overseas, often through branches or subsidiaries. JPMorgan, the nation's biggest bank by assets, often derives as much of its quarterly revenue from global operations as from those in the U.S., Associate General Counsel Don Thompson said last year.
CFTC Chairman Gary Gensler has pushed for a broad reach of Dodd-Frank rules because of the potential for trades overseas to flow back to institutions in the U.S. and possibly put taxpayers at risk. He has frequently cited the 2008 collapse of AIG as a warning.
"Risk also comes crashing back to our shores from overseas when a run starts in any part of a modern, global financial institution," Gensler said in a June 6 speech to an industry conference in New York.
Treasury Secretary Jacob J. Lew held a meeting last week with Gensler and Securities and Exchange Commission (SEC) Chairman Mary Jo White, whose agency is also working on derivatives rules, to improve discussions about the cross-border issue, according to a person familiar with the meeting who requested anonymity because it was private. Gensler and the CFTC were urged to share more information about its process, the person said.
'Cooler Heads'
Fourteen Republican and Democratic members of the House Agriculture Committee, which oversees the CFTC, today called on Lew to intervene in the rulemaking process. The members called on Lew to direct the 10-member Financial Stability Oversight Council (FSOC) to resolve uncertainty in the market generated by the debate. "Cooler heads must prevail," the Representatives—including K. Michael Conaway, a Texas Republican, and David Scott, a Georgia Democrat—said in the letter.
A temporary exemptive order that the agency completed last year expires on July 12, prompting the agency's four commissioners, particularly Gensler and Democrat Mark Wetjen, into a last-minute negotiating session. Jill E. Sommers stepped down yesterday as a Republican commissioner, leaving an open spot on the five-member panel.
"This thing needs to be resolved one way or another by the 12th," Bart Chilton, one of three Democrats, said yesterday. "If we can reach a resolution prior to the meeting, great. If we can't, let's meet and hammer it out there."
Thirteen lobbying groups representing Wall Street, overseas banks, and other companies urged senators to work with the CFTC and SEC to delay the deadline. The groups, including the Securities Industry and Financial Markets Association and International Swaps and Derivatives Association Inc., asked for a delay of at least six months to allow for increased coordination between U.S. and foreign authorities.
Commissioners are discussing three documents: final guidance for how Dodd-Frank rules ought to be applied, a phase-in process, and a separate letter on some transaction and record-keeping rules providing that European requirements are essentially identical, according to a one of the people with knowledge of the process. Gensler and CFTC employees have been in negotiations with European regulators on the letter, the person said.
One of the biggest debates is when the CFTC will allow companies to comply with overseas rules to substitute their compliance with Dodd-Frank. Commissioners are negotiating when and how that process will be applied and whether firms located in the U.S. might be eligible for substituted compliance when they are on one side of a trade with non-U.S. counterparties.
'Moral Hazard'
"People are perpetuating this lie that if we don't extend our reach to U.S. entities operating elsewhere they won't be regulated," Sommers said in a telephone interview.
"It is in fact moral hazard for the CFTC to claim we have the resources to do this. We should want the help of global regulators," Sommers said. "That's unfortunately not the view of the chairman."
The EU has said that a solution to the dispute lies in a so-called equivalence, or substituted compliance system, in which U.S. regulators would accept that EU rules are as robust as U.S. standards, and so avoid imposing additional requirements on EU-based banks.
Equivalence and substituted compliance are "the only way forward to protect financial stability, while allowing the financial sector to allocate capital efficiently throughout the world," Calvino said.


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Death notices for March 18, 2014
Sandy L. Bouton, 62, Janesville, died Saturday at home. Services will be at 11 a.m. Saturday at Whitcomb-Lynch Funeral Home, Janesville. Visitation will be from 10 a.m. until the time of services Saturday at the funeral home.
Charlotte P. Flock, 77, Janesville, died Monday at home. Arrangements are pending with Brian G. Mark Funeral Home, Beloit Chapel.
Norman O. Miethke, 85, Sharon, died Friday at Mayo Franciscan Health Care Center, La Crosse. Arrangements are pending at Toynton Sharon Funeral Home.
Irene M. Sculley, 86, Lake Geneva, died Saturday at home. Services will be noon Saturday at the Lake Geneva United Methodist Church, Lake Geneva.� Visitation will be from 10 a.m.� until the time of services Saturday at the church. Derrick Funeral Home & Cremation Services is assisting the family.