text:
NMR Spectroscopy as a Robust Tool for the Rapid Evaluation of the Lipid Profile of Fish Oil Supplements
1Department of Food Science and Technology, The Ohio State University, 2Foods for Health Discovery Theme, The Ohio State University
1Department of Food Science and Technology, The Ohio State University, 2Foods for Health Discovery Theme, The Ohio State University
1Institute of Interfacial Process Engineering and Plasma Technology, University of Stuttgart
1Institute of Chemistry, Biology of Membranes, Nanoobjects, UMR5248 CNRS, Université de Bordeaux
1Institut für Medizinische Mikrobiologie, Universitätsmedizin Göttingen
1Department of Electrical and Computer Engineering, Schulich School of Engineering, University of Calgary, 2Department of Radiology, University of Calgary
1Centre d'optique, photonique et laser, Université Laval, 2Département de physique, Cégep Garneau
1In Vivo Multifunctional Magnetic Resonance center, Robert C. Byrd Health Sciences Center, West Virginia University, 2Department of Biochemistry, West Virginia University School of Medicine, 3Department of Microbiology, Immunology & Cell Biology, West Virginia University School of Medicine
1Interdisciplinary research center HALOmem, Martin Luther University Halle-Wittenberg, 2Department of Chemistry, Kings College London
1Department of Physics, Central Washington University, 2Department of Physics, University of Wisconsin-La Crosse, 3College of Science and Technology, Millersville University
1Centre de Résonance Magnétique Biologique et Médicale, UMR 7339 CNRS, Faculté de Médecine, Aix-Marseille Université, 2Centre de Recherches en Oncologie Biologique et Oncopharmacologie, UMR 911 INSERM, Faculté de Médecine, Aix-Marseille Université
1Department of Chemistry, University of North Carolina at Charlotte, 2Nanosys Inc.
1School of Science and Computer Engineering, University of Houston-Clear Lake, 2Airgas Specialty Gas, Airgas USA LLC
1UMR8576, CNRS, Lille University, 2UMR-S1172, INSERM CNRS, Lille University
1Biomedical Engineering, Duquesne University, 2Department of Computer Science, University of Missouri, 3Department of Bioengineering, University of Missouri
1Department of Chemistry, University of the Pacific
1Department of Ecology and Evolutionary Biology, University of California, Irvine, 2School of Life Sciences, University of Sussex
1Institut für Hochfrequenztechnik, Hochschule für Telekommunikation, Leipzig
1Department of Nuclear Science and Engineering, Massachusetts Institute of Technology, 2Department of Physics, Massachusetts Institute of Technology, 3Plasma Science and Fusion Center, Massachusetts Institute of Technology
1Department of Physics, Ludwig Maximilian University of Munich, 2Physics and Astronomy Department, King Saud University, 3Max Planck Institute of Quantum Optics
1Morgan-Botti Lightning Laboratory, Advanced High Voltage Research Centre, School of Engineering, Cardiff University
1Department of Chemistry and Biochemistry, University of Denver, 2Magnetic Imaging Group, Applied Physics Division, Physical Measurements Laboratory, National Institute of Standards and Technology, 3Department of Radiology, Geisel School of Medicine, Dartmouth University, 4Department of Biochemistry, West Virginia University, 5Department of Electrical and Computer Engineering, University of Denver, 6Department of Engineering, University of Denver
1ARC Centre of Excellence in Plant Cell Walls, School of BioSciences, University of Melbourne
1Experimental Molecular Biophysics, Freie Universität Berlin
1School of Physics and Astronomy, University of Southampton, 2Department of Physics, University of Warwick, 3Institut des Matériaux Jean Rouxel, University of Nantes CNRS
1Department of Applied Physics, Eindhoven University of Technology, 2Dutch Institute for Fundamental Energy Research
1Department of Physics, University of Alberta
Source: David C. Powers, Tamara M. Powers, Texas A&M
In this video, we will carry out the photochemically initiated polymerization of styrene to generate polystyrene, which is an important commodity plastic. We will learn the fundamentals of photochemistry and use simple photochemistry to initiate radical polymerization reactions. Specifically, in this module we will examine the photochemistry of benzoyl peroxide and its role as a photo-initiator of styrene polymerization reactions. In the described experiments, we will investigate the role of wavelength, photon absorption, and excited state structure on the efficiency (measured as quantum yield) of photochemical reactions.…
1Department of Chemistry, Central Washington University, 2Department of Chemistry, Utah Valley University
1United Graduate School of Agricultural Science, Tokyo University of Agriculture and Technology, 2Faculty of Agriculture, Tokyo University of Agriculture and Technology, 3Institute of Agriculture, Tokyo University of Agriculture and Technology
1Fischell Department of Bioengineering, University of Maryland, 2Wellman Center for Photomedicine, Harvard Medical School, Massachusetts General Hospital, 3The Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology
1Biomedical Engineering Department, Ben-Gurion University of the Negev, 2Ilse Katz Institute for Nanoscale Science and Technology, Ben-Gurion University of the Negev
1Unité de Génomique Virale et Vaccination, Virology Department, Institut Pasteur, CNRS UMR3569, 2Unité de Chimie et Biocatalyse, Biochemistry and Structural Biology Department, Institut Pasteur, CNRS UMR3523, 3Unité des Interactions Moléculaires Flavivirus-Hôtes, Virology Department, Institut Pasteur
1School of Mathematical and Natural Sciences, Arizona State University, 2Applied Maths NV
1European Commission, Joint Research Centre (JRC)
1Department of Chemistry, University at Albany-SUNY
1Department of Chemistry, The Hebrew University of Jerusalem, 2Wolfson Centre for Applied Structural Biology, The Hebrew University of Jerusalem
1School of Physics and Astronomy, University of Exeter, 2Department of Physics and Geology, University of Perugia, 3Istituto Officina dei Materiali del CNR, Unità di Perugia
1Institute of Imaging Science, Vanderbilt University, 2Department of Radiology and Radiological Sciences, Vanderbilt University, 3Department of Biomedical Engineering, Vanderbilt University, 4Department of Molecular Physiology and Biophysics, Vanderbilt University, 5Department of Physical Medicine and Rehabilitation, Vanderbilt University, 6Department of Physics and Astronomy, Vanderbilt University
Source: Laboratory of Dr. B. Jill Venton - University of Virginia
Ultraviolet-visible (UV-Vis) spectroscopy is one of the most popular analytical techniques because it is very versatile and able to detect nearly every molecule. With UV-Vis spectroscopy, the UV-Vis light is passed through a sample and the transmittance of light by a sample is measured. From the transmittance (T), the absorbance can be calculated as A=-log (T). An absorbance spectrum is obtained that shows the absorbance of a compound at different wavelengths. The amount of absorbance at any wavelength is due to the chemical structure of the molecule. UV-Vis can be used in a qualitative manner, to identify functional groups or confirm the identity of a compound by matching the absorbance spectrum. It can also be used in a quantitative manner, as concentration of the analyte is related to the absorbance using Beer's Law. UV-Vis spectroscopy is used to quantify the amount of DNA or protein in a sample, for water analysis, and as a detector for many types of chromatography. Kinetics of chemical reactions are also measured with UV-Vis spectroscopy by taking repeated UV-Vis measurements over time. UV-Vis measurements are generally taken with a spectrophotometer. UV-Vis is also a very popular detector for other analytical tech…
1Vanderbilt Brain Institute, Vanderbilt University Medical Center, 2Department of Psychology, University of Toronto, 3Department of Hearing and Speech Sciences, Vanderbilt University
1Human Genetics and Cognitive Functions, University Paris Diderot, CNRS UMR 3571, Institut Pasteur, 2Neurophysiology and Behavior, University Pierre et Marie Curie Paris 6, CNRS UMR 7102, 3Bio Image Analysis, CNRS URA 2582, Institut Pasteur
1Physical Sciences Division, Pacific Northwest National Laboratory
1Department of Physics, University of Miami
Source: Laboratory of Dr. Ryoichi Ishihara — Delft University of Technology
Raman spectroscopy is a technique for analyzing vibrational and other low frequency modes in a system. In chemistry it is used to identify molecules by their Raman fingerprint. In solid-state physics it is used to characterize materials, and more specifically to investigate their crystal structure or crystallinity. Compared to other techniques for investigating the crystal structure (e.g. transmission electron microscope and x-ray diffraction) Raman micro-spectroscopy is non-destructive, generally requires no sample preparation, and can be performed on small sample volumes. For performing Raman spectroscopy a monochromatic laser is shone on a sample. If required the sample can be coated by a transparent layer which is not Raman active (e.g., SiO2) or placed in DI water. The electromagnetic radiation (typically in the near infrared, visible, or near ultraviolet range) emitted from the sample is collected, the laser wavelength is filtered out (e.g., by a notch or bandpass filter), and the resulting light is sent through a monochromator (e.g., a grating) to a CCD detector. Using this, the inelastic scattered light, originating from Raman scattering, can be captured and used to construct the Raman spectrum o…
1Davis Heart and Lung Research Institute, The Ohio State University, 2Laboratory of Clinical Investigation, National Institute on Aging, 3Division of Endocrinology, Diabetes and Metabolism, The Ohio State University, 4Department of Human Sciences, Human Nutrition, The Ohio State University, 5Division of Endocrinology and Diabetes, Department of Pediatrics, University of Pennsylvania
1School of Chemistry, The Australian Centre for Nanomedicine and the ARC Centre of Excellence in Convergent Bio-Nano Science and Technology, The University of New South Wales
1Department of Physics, University of Wisconsin - Milwaukee, 2Department of Biological Sciences, University of Wisconsin - Milwaukee
1Dutch Institute for Fundamental Energy Research, 2University of Trento, 3Eindhoven University of Technology
1Center for Biophotonics Science and Technology, University of California, Davis, 2Department of Pathology and Laboratory Medicine, University of California, Davis
1Department of Physics, National Taiwan University, 2Department of Applied Physics, Osaka University, 3Molecular Imaging Center, National Taiwan University


text:
The Carl C. Anderson, Sr. and Marie Jo Anderson Charitable Foundation Laboratory
About the Neuroblastoma Research Program
The Texas Children's Cancer Center neuroblastoma research program is dedicated to laboratory and clinical research focused on increasing our understanding of neuroblastoma and developing new and more effective therapies. Our current research efforts focus on understanding the causes of neuroblastoma, identifying new targets for treatment, and evaluating the efficacy of new therapies.
Neuroblastoma is the most common solid tumor in childhood and accounts for almost 10% of childhood cancers. While children with low- and intermediate-risk neuroblastoma have cure rates of over 90%, approximately 40% of children with neuroblastoma have "high-risk" tumors with much lower survival rates, despite aggressive treatment with combinations of chemotherapy, stem cell transplantation, surgery, and radiation therapy. Cases of "high-risk" neuroblastoma are also associated with frequent recurrences and tumors that are resistant to treatment. New treatments are needed for these children to improve the cure rates and reduce the occurrence and severity of the side effects of treatment.
Research is an ongoing priority for the Neuroblastoma Program at Texas Children's Cancer Center, and our doctors and scientists are continuously striving to translate laboratory discoveries into new treatments for children with neuroblastoma. Our current research efforts focus on understanding the causes of neuroblastoma, identifying new targets for treatment, and evaluating the efficacy of new therapies. Texas Children's Cancer Center has a large number of laboratories devoted to studying the causes of neuroblastoma and to developing new treatments that can be advanced into clinical trials for children with neuroblastoma. Recent discoveries by Texas Children's Cancer Center scientists include:
- identification of novel microRNA's associated with aggressive neuroblastoma (Shohet et al 2011)
- identification of a novel set of circulating biomarkers associated with neuroblastoma (Egler et al 2011)
- identification of novel proteins involved in neuroblastoma resistance to chemotherapy (Shang et al 2010, Zage et al 2012)
- identification of a novel protein associated with neuroblastoma tumor cell growth (Vasudevan et al 2009)
- identification of novel immunotherapy and antiangiogenic treatment combinations effective against neuroblastoma (Louis et al 2011, Patterson et al 2011, Zage et al 2010)
- identification of a novel role for tumor-associated macrophages in the growth of neuroblastoma tumors (Liu et al 2012)
Future research by the scientists in the Neuroblastoma Program at Texas Children's Cancer Center will continue to explore new pathways, new targets, and new treatments in order to provide the most appropriate and most effective therapy for each and every child with neuroblastoma.
Our Researchers
Jason Shohet, MD, PhD
Leonid Metelitsa, MD, PhD
Saurabh Agarwal, PhD
Eveline Barbieri, MD, PhD
Chris DeRenzo, MD, MBA
Andras Heczey, MD
Chrystal Louis, MD, MPH
Leonid Metelitsa, MD, PhD
Bilal Omer, MD
Robin Parihar, MD, PhD
Barbara Savoldo, MD, PhD
Sarah Whittle, MD
Jianhua Yang, PhD
Ananth Annapragada, PhD

subset: commoncrawl


text: Beirut - Hezbollah's leader says authorities will never be able to arrest four members of his militant group who have been indicted in the murder of a former Lebanese prime minister.Sheik Hassan Nasrallah said on Saturday in a televised address that "even in 300 years" the men will not be turned in. The Shi'ite militant group denies any role in the killing.Nasrallah's speech marked his first comments since the indictment was announced on Thursday. A high-ranking Hezbollah militant and three others were accused in the 2005 assassination of Rafik Hariri.Narallah insists the tribunal is dominated by America and Israel and calls its decision "an aggression against us and our holy warriors".


text:
If you are seasoned or a new graduate I'm looking for YOU!!!!I'm looking to hire a CNA or a CMA or a HHA or two for my father in law who has dementia. If you are newly graduated or not, you will have hands on training right along side of me. He needs help bathing, dressing, feeding, grooming, laundry, light housekeeping. Daytime hours. Please call and leave a message to set up an interview or ask any questions.
Related Listings:
CNA's and Certified HHA's Wanted (Folcroft)
CNA/CMA (Bismarck, ND)
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CNA/CMA needed (Charlotte)
CNA/CMA Positions (Enid, OK)
Please enter your phone number and click "Send" to receive the listing details by SMS. For numbers outside the US, please enter the country code, for e.g. +91. If you do not receive a message, your phone number might be registered in the Do Not Disturb Registry.
For numbers outside the US please enter the country code.
Please enter your phone number and click "Call" to call the listing owner.
For numbers outside the US please enter the country code.


text:
Printz Award-winning author Meg Rosoff wrote her latest book, There is No Dog, by doing what she calls "thinking sideways." To do this Meg says, "You have to train yourself to tilt your head a little bit to the side and squint at the world; to see it from a slightly different angle." For the Thinking Sideways Contest, we challenged you to turn one of your favorite stories upside-down.
The entry period is now over, but you have another five days to vote! Voting will run until April 23, 2012 at 11:59 p.m. EST, at which point the 10 most-hearted entries will be judged by the Figment editorial team.
One grand-prize winner will receive a class set of 30 copies of There is No Dog for his or her school and a personal set of 20 awesome YA titles from Penguin. Nine runners-up will each receive smaller (but still super exciting) sets of 4 teen titles from Penguin.
So check out the stories below, and get voting!


text:
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text:
Ending on a high note
December 31, 2012
We've gotten a few complaints this year about how much time we've spent talking about open access instead of dinosaurs. Brian Engh is in the more-dinosaurs faction, but he doesn't just whinge about our non-dino coverage, he does something about it. He writes:
here's the deal:when sv-pow becomes more discussion about human things and less discussion about ancient monsters i bombard your email with whatever crappy unfinished dino-drawings i got lying around. you have my permission to do with these as you wish, however if they end up on SV-POW i will be happy and feel i'm doing my part to combat humans.
Happy new year, sauropod fans. Enjoy this rearing Dicraeosaurus courtesy of Brian.
Best. Exhibit. Ever.
December 13, 2011
Brachiosaurus and friends from here (hat tip to Ville Sinkkonen).
In an e-mail with explicit permission to quote, our colleague Casey Holliday sent the following thoughts about our new paper and the subsequent ten days of related blogging:
I don't know guys. I like your blogs, and your papers are fine. And I liked this paper. And I'm a fan. But it looks to me that you blogged about far more data, in- or not in support of your paper than you actually presented in your paper. So,…wtf? The posts on Dinomorph far exceeded your (or any) published rebuke. Your explanation (and honorable erred parts) of the semicircular canal data also exceeded that actual published part too, with extra photos, description etc. (is that error going to be OA published too?) Also additional pix of necks (e.g., Nigersaurus), and not only from sauropods that would have
potentially bettered the original pub. So what's fair? Why weren't
these data also included in the publication? Maybe it's not my business and was taken up in review…I don't know. Frankly, none of this blog stuff really counts in the peer-reviewed world of "real" publications. Its not like this blogging and comments all count as Supplementary Data either. But also, I'm obviously here commenting on it, so also crossing into the fray…But who really cares about all this discussion? Its no different than the DML or any other noise in the internet world (or is it). Similar to what Paul Barrett was posting on Tet Zoo…what counts? Why take up arguments here, when they should (maybe?likely?) be taken up more formally and privately.
If you're going to air all this additional data and unreviewed
opinion, then I think this discussion is important.
I think this phenomenon of the sauropod neck paper is really
interesting. We have 3 scientists that published a paper, and then, thanks to their current blogosphere cred, basically unleashed a hype not seen in this way previously that I can remember. Maybe that's the interesting part? and kudos. But interestingly…we're seeing this intersection of traditional publication (OA or not), blogosphere description, and perhaps, almost certainly, excellent self-promotion.
I'm still a fan. I think this paper is generally solid. But I'm
particularly interested in this phenomenon and hope this is a fair
place to raise it.
The comment field is open, and we SV-POW!sketeers are going to refrain from commenting for a couple of days to let the conversation develop unfettered.
We are genuinely curious to know what you think.
Shedloads of Awesome, part 3: Dicraeosaurus
December 21, 2008
In view of all the awesome that is the Humboldt Museum's gigantic brachiosaur mount, it's too easy to overlook another nearly-complete Tendaguru sauropod, mounted in the very same hall, that is also worthy of respect and, yes, awe. Ladies and gentlemen, I give you: Dicraeosaurus hansemanni!
Dicraeosaurus is a member of Dicraeosauridae, the family that, together with Diplodocidae makes up the whip-tailed clade Flagellicaudata; which in turn, with rebbachisaurids and a few bits and pieces, makes up the great neosauropod clade Diplodocoidea. Dicraeosaurus was first named and briefly described by Janensch (1914:83); typically, Janensch went on to make full and detailed descriptions of its osteology, and also to describe the mounted skeleton (Janensch 1936).
It's not really apparent from the photo above, but Dicraeosaurus is really small — like, embarrassingly small. Especially when it's standing next to Brachiosaurus brancai. Gunga et al. (1999) estimated its mass at 12810 kg, but since that was the same paper that estimated B. b. at 74420 kg, based on a similarly grotesque baloon model, we can probably assume an accurate mass would be about one third of that, or 4000-5000 kg. Smaller than a big elephant. (I don't know of any other published mass estimates for Dicraeosaurus; if I've missed any, please shout.) This is typical for dicraeosaurs: the South American Amargasaurus and Brachytrachelopan are even smaller.
Dicraeosaurs are interesting for several reasons. One is the dwarfism, and attendant shortening of the neck (which is taken to the extreme by Brachytrachelopan: reconstructed, that baby looks more like an ornithopod). But maybe most interesting is the peculiar construction of the vertebrae, which have very tall neural spines:
Check this out. The spines of C2-4 slope backwards; that of C5 is upright; from C6 onwards, they slope forwards. Very strange. Oh, and this is real: the verts are in good shape, and definitely not distorted.
One thing that Matt and I have been working on recently is the mechanics of sauropod necks, and particularly the attachment points of the epaxial ligaments and muscles. Among diplodocids and other sauropods with bifid neural spines, you occasionally find a nice clear ligament attachment knob in the floor of the trough between the metapophyses (i.e. the paired neural-spine halves) — but the Humboldt Dicraeosaurus mount is the first specimen I've ever seen that has such a knob at the base of every single cervical's metapophyseal trough. See for yourself:
Unfortunately, as I was taking this last photo, and others like it, I came in a bit too close to the neck and touched one of the left cervical ribs (around C5). Aaaand off it came, to shatter on the hard flooring. It was a horrible moment … especially as I did it right in front of the curator, noted dicraeosaur lover Daniela Schwarz-Wings. With his usual impeccable tact, Matt took the opportunity of snapping a photo of me showing her the pieces, and trying to show how two of them fit together. Two more fragments lie on the floor at her feet:
Happily, the museum's crack conservation unit swung into action immediately — I mean, literally within an hour — and I believe that rib is now back in place and as good as new. Frightening.
The tall, bifid neural spines of dicraeosaurs continue into the dorsal sequence, resulting in a "tall back" that carries through the sacrum and into the anterior part of the tail — as the posterolateral view below sort of shows. Just as the dicraeosaurid neck-shortening trend is taken to its extreme by Brachytrachelopan, so the elongation of neural spines reaches its apotheosis in Amargasaurus, which we must remember to show you one of these days.
Update (22 December)
David Hone, of Archosaur Musings fame, has sent me this photograph of the Dicraeosaurus mount in the process of being put together by the good people at RCI.
Janensch, Werner. 1914. Ubersicht uber der Wirbeltierfauna der Tendaguru-Schichten nebst einer kurzen Charakterisierung der neu aufgefuhrten Arten von Sauropoden. Archiv fur Biontologie, Berlin, III, 1 (1), pp. 81-110.
Janensch, W. 1936. Ein aufgestelltes Skelett von Dicraeosaurus hansemanni. Palaeontographica (suppl. 7), 299–308.


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GraphicRiver Restaurant Menu Labels 8282174
Category: Stock Vector | Comment: ( 0 )
GraphicRiver Restaurant Menu Labels 8282174
Stock Vector \ Decorative \ Decorative Symbols
Premium \ Quality \ Plate \ List \ Kitchen \ Label \ Restaurant \ Wine \ Symbol \ Sweet
Stock Vector - Restaurant Menu Labels 8282174 by macrovector @ GraphicRiver
Stock Vector \ Decorative \ Decorative Symbols
Graphics Files Included: JPG Image, Vector EPS; Layered: No; Minimum Adobe CS Version: CS.
Restaurant menu coffee and tea wine list labels set isolated vector illustration.Editable EPS and Render in JPG format
Comunication Background; Comic Speech Bubbles; Contact Us Service Icons; Set of Kids; Oil Industry Composition; Business Meeting in Top View; Business Meeting in Top View.
Keywords: badges, banner, chef, collection, cooking, decorative, design, dinner, dish, drink, element, emblem, food, hat, icon, juicy, kitchen, label, list, plate, premium, quality, restaurant, set, sign, stamp, sweet, symbol, tag, wine.


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These devices inject reactance to push power away from a given transmission circuit. Guardians are either installed on each phase conductor (PowerLine Guardian®), or in a Smart Bank™ or Smart Tower™ placed within the transmission right-of-way or in existing substation space (Power Guardian™). The number of devices per phase is determined by the amount of compensation required as each device injects a fixed amount of reactance. The devices can be remotely controlled or programmed to activate automatically based on current set points.
Smart Bank™ – Power Guardian
This method consists of multiple metal structures, each carrying multiple Power Guardians. This extremely high-density deployment can be constructed on a small footprint within an existing right-of-way, a substation or a dedicated parcel of land.
Smart Tower™ – Power Guardian
This tower can replace an existing structure within a circuit or serve as a new dedicated tower in the middle of a span. Utilities needing to replace old poles or towers can use this method to upgrade their infrastructure and simultaneously add power flow control capabilities to their system.
Conductor Mounted Spread Deployment – Powerline Guardian
This method is available for the PowerLine Guardian® and is best suited for relatively small deployments and/or circuits with sufficient length. Mounting PowerLine Guardians on a conductor is generally the fastest deployment option for utilities wishing to address power flow in a vastly compressed timeline.
Compact Deployment – Powerline Guardian
In this method, many more PowerLine Guardians can be installed on each span. Compact deployment usually involves reconductoring a small line section and/or installing a few new poles. This method allows utilities to choose a preferred location along a circuit, meaning they can completely avoid disturbing residential areas or environmentally sensitive regions.
Guardian technology being installed in Little Falls, MN.


text:
Before you start wondering WTF the MacTexan is doing talking about Linux, let me ask you a couple of questions first.
If you answered "yes" to any one of these questions then I highly recommend you download your Linux distro of choice and get busy. In a couple of hours, you'll have a mature, polished operating system installed complete with a photo editor, music and movie player and a complete office suite.
A couple years ago I wouldn't make that recommendation, but there are now three or four Linux distributions I would feel comfortable installing for my parents. They are that stable and that user-friendly. OK, OK. Why does the MacTexan recommend Linux? Three reasons:
Before you start swearing, I still believe macOS is the best desktop operating system in the world, but let's face it, the rather expensive cost of entry is beyond what many are either willing or able to pay. Even if you already own a Mac, having a second computer in the home is handy and becoming more frequent than not. If you are a Mac geek (like myself), then setting up and using a Linux machine is a snap. Since both OSs are based on a UNIX variant, their terminal commands are 90% identical. There's even a Linux distribution called Elementary who's GUI is so similar to macOS you have to look closely to distinguish the two. So, even if you are a Mac geek, that doesn't mean tech must originate in Cupertino to be cool. Linux has been cool for some time, but you needed to be a command-line wizard to make it work properly. While I must admit to spending quite a bit of time in the Linux terminal, it's by choice, not necessity. For the most part, today's popular Linux distributions simply install and run.
Ubuntu is by far the most popular Linux distribution and that's important if you like to customize the GUI and task the machine for more than typical desktop use. You see, unlike commercial operating systems, Linux distributions are open-source. That means the OS is developed and maintained by its users or its "community". The more popular an open-source project is, the more people develop software for it and the more people are available for support. I've never run into a question about Ubuntu I couldn't answer quickly with a simple Google search that points me to one of the many hundreds of Linux forums where my question is being discussed.
My favorite Linux distro (Linux bit-weenie shorthand for "distribution") is an Ubuntu variant called Ubuntu Mate. If you're a competent Windows XP or Windows 7 user, Ubuntu Mate is a slam dunk. If you have an old Windows XP or Windows 7 machine sitting in a closet somewhere that, like most old Windows computers, got so slow over time as to become unusable, then Ubuntu Mate can breathe life back into it and make it a very functional computer again. Mate is designed from the ground up to be "lean and mean". If you have a ten-year-old Pentium or Core Duo computer that will barely boot Windows XP, I guarantee Ubuntu Mate will make the old machine sing again. Also, Mate's GUI is so Windows-like you will be immediately proficient.
All the above-mentioned Linux distributions come with everything you need to be productive as soon as you finish installing them. All include a web browser, photo editor, music and movie player, an email application and a complete office suite that both reads and saves files in MS Office formats. If you need more, there are tens of thousands of open-source software titles available for free download. Some are names you're familiar with like Firefox, Chrome, VLC, Dropbox and Skype to name a few.
All Linux operating systems are more secure than Windows for a couple of reasons. First, their kernels are based on UNIX, built from the ground up with security in mind. Second is the "security by obscurity" model. Simply put, there are so few Linux computers compared to those running Windows that the bad guys don't spend much time trying to exploit them. I've been running an Ubuntu machine on my home network for over ten years. I've never installed antivirus software and the machine has never been compromised. Of course, your results may vary.
I'm a long way from calling 2017 "the year of the Linux desktop", (lots of geeks have made idiots of themselves with that pronouncement) but I do think it's time for "normal" computer users to give Linux a try. I won't go so far to say you should wipe your Mac or Windows machine (well, maybe Windows) and replace its OS with Linux. But, it is a shame to let an older PC or laptop languish unused in the back of a closet or in a junk drawer when all it takes is an hour of your time to revitalize it. Yes, unless the old machine has physical problems, there is definitely a Linux distro that will turn it into a like-new machine. That's been true for some years now. Today, the difference is you don't have to be a geek to make it work.


text:
|Ten Nights at Freddy's: The Addition of Freddy's Castle
|Scott Cawthon & NovaPen Productions
|Windows, iOS, Android
|Release Date(s)
|February 25th, 2015
|Point and Click, Horror
|Five Nights at Freddy's
| Five Nights at Freddy's
Five Nights at Freddy's 2
|Media Included
Ten Nights at Freddy's: The Addition of Freddy's Castle, also known as TNaF, is an indie point-and-click horror game. The goal is for the player to try to survive the night at Freddy Fazbear's Pizza and Castle while avoiding getting caught and killed by the animatronics. It is the sequel of Five Nights at Freddy's 2. The game features new animatronics and new locations.
Welcome back to the new and improved Freddy Fazbear's Pizza (again)! Due to popular demands, we have introduced new animatronics into our restaurant. And get this? We've even created a tourist attraction known as Freddy's Castle which features much more animatronics! We have also decided to attempt to make the restaurant bigger, constructing new rooms for more customers!
So why are you here?
Well, your job is to monitor the cameras and make sure that nothing goes wrong. And after you have completed five nights at Freddy's Pizza, you will be able to spend five more nights at Freddy's Castle!
Well that is all I have to say. Just remember! Check those cameras and doors carefully and if an animatronic is near you, good luck!
As always, Fazbear Entertainment is not responsible for death or dismemberment.
The player sits in an office and monitors security cameras positioned throughout the restaurant or castle (depending on the player's progress) to observe the animatronic mascots. The player has a limited amount of power to view camera feeds, light hallways, flash camera monitor viewings and close the doors.. The player must use the camera feed locations in the building, and hold the animatronics off using the doors. If the player fails to do this, they will be killed with a jumpscare or other method. To advance to the next night, the player must survive from 12:00 AM until 6:00 AM (10 minutes of torture in real time).
New Features
- Ability to cover vents with grates (only for five seconds as the grates are worn out allowing the animatronics to break through).
- Puppet Mask to scare away the animatronics if they break through the vent or come through the hallway.
- Emergency Button to close both doors and vents immediately. Wastes 2% power for each use.
- Mini Generator to gain 1 power every 20 seconds.
|Kenny Matthews
Kenny has pale skin and a black fringe as seen in the end cutscene. Kenny is believed to be very focused and competent, withstanding 20 animatronics for ten nights of brutal torture. He is also the only one other than Jeremy not to be fired. Instead, he jumps out the window behind him at the end of Custom Night, fleeing from a mysterious animatronic only seen by his shadow...
|Phone Guy
This Phone Guy is a new variation as there was apparently another security guard in between Mike Schmidt and Kenny Matthews' employment periods. He is afraid to death, often shouting and shutting doors often. Believing he is safe, he advises Kenny on the behaviours of each animatronic. Phone Guy dies in the end as you can hear his shriek before hearing a wall being smashed.
|Phone Guy #2
This Phone Guy was the previous security guard who watched over Freddy Fazbear's Castle. He sounds very tough and strong, as you can often hear him punching the walls and shouting threats at the animatronics. Phone Guy #2 also dies in the end as you can hear him struggling with an animatronic before hearing a slash of an axe.
Freddy Fazbear's Pizza
|Starting Location
|Freddy Fazbear
|Show Stage
He will only become active early in the week if the player runs out of electricity, at which time the player will be greeted by his illuminated face, and the Toreador March before being attacked. From the 3rd night onward, he will become active. When Freddy starts to move, a deep laugh is heard instead of footsteps. Freddy only moves when the cameras are down. Freddy can only enter The Office via the East Hall.
|Bonnie the Bunny
|Show Stage
Bonnie is known for returning to The Office more frequently than the other animatronics, and he only approaches from the left side. He will stare through the doorway into The Office, unlike Chica, who looks through the window. Bonnie also has a special ability in which he can disable the cameras temporarily as he moves to another area, as does Chica.
|Chica the Chicken
|Show Stage
Chica will generally head towards the player's position, similar to Bonnie, but she also wanders to the Kitchen and Restrooms. As opposed to Bonnie, Chica will show up at the door less often, but will generally linger there, waiting longer and stealing more of the player's energy, whereas Bonnie will show up often but leave quickly.
|Perry the Penguin
|Show Stage
On the early nights, he is normally very idle, with almost no chance of attacking on Nights 1 or 2. On Night 3, he will walk around, but will not target you. On Night 4, however, he will become a major threat, and is sometimes capable of disabling 2 random camera views every time he attacks (though he normally only disables 1) and he attacks often. He can attack almost 4 times a night after Night 3. His behaviour in Night 5 is around the same, though on Night 5 he is triggered slightly earlier.
|Foxy the Pirate Fox
|Pirate Cove
Foxy hides behind his curtain in Pirate Cove throughout the game. Over the course of the night, the player must use the Monitor periodically. They must also check Pirate Cove in a balance between "too much" and "too little" to keep Foxy from emerging from his curtain and sprinting toward the Office. This balance can be difficult to find, but it is essential to surviving the night without Foxy coming to end it. Foxy's attacks seem to be based on a timer, rather than being random.
|Kid's Cove
Mangle begins the night in a corner at Kid's Cove, in a contorted heap of machinery. Once activated, it will mainly travel the pizzeria via the ceiling. Mangle does not try to enter the Office from the hallway. Mangle also may frequently appear in the same room with other animatronics. When the Mangle moves into or out of a room that is monitored by the cameras, a static feed will occur.
|Larry the Lion
|The Attic
Larry and Terry work in unison, usually always in the same room, but lower down they split up and are always in opposing rooms (e.g. Larry is in West Hall, Terry must be in East Hall). When one is at the door, you have to shut both (alternatively, if one door is shut, the other at the opposing door is unable to get in.)
|Terry the Tiger
|The Basement
Larry and Terry work in unison, usually always in the same room, but lower down they split up and are always in opposing rooms (e.g. Larry is in West Hall, Terry must be in East Hall). When one is at the door, you have to shut both (alternatively, if one door is shut, the other at the opposing door is unable to get in.)
|Balloon Boy
|Game Area
BB starts in the Game Area and will eventually come to The Office via the Left Air Vent. With each of his movements, the player can hear him saying "Hello" and "Hi". BB will not show up on any other cams, except the Game Area and the Left Air Vent, making his location hidden. If the player pulls up the monitor while BB is in the Left Air Vent's blind spot, he enters The Office, laughing constantly. Once inside, he disables the Flashlight and the Left and Right Air Vents' blind spot lights.
|The Puppet
|Prize Corner
The player needs to keep the Music Box wound, as the animatronics seem to have some sort of problem where having no noise will cause them to malfunction and try to find sources of noise; in this case, the player's office. Keeping the Music Box wound is vital; if it is left unwound for too long, the Puppet will come out of his box and the player will be attacked, receiving a game over.
|Marty the Mammoth
An extremely dangerous animatronic that is in several pieces, and the other animatronics can assemble him while the camera is down. When fully functional, Marty runs straight for the Office, crushing the player which results in a Game Over. It is necessary to check the cameras once in a while to make sure that he is not being built. There are 8 parts of him located in each room and the finished model will be located in Parts/Services.
|Golden Freddy
|Security Office
It is currently unknown where (if anywhere) Golden Freddy starts from. At random, Golden Freddy can instantly appear in The Office or the hall just outside the office, plopped down in a similar position he was in the first game or just his head floating in the distance, respectively. Shortly afterward, his body will vanish, only for his head to rush at the player and kill them if they do nothing to counter him. To prevent being killed by Golden Freddy, the player must immediately shut both doors once they spot him in the Office, or turn off the Flashlight when he's in the hallway.
Freddy Fazbear's Castle
|Starting Location
|Freddy the King
|Throne Room
He will only become active early in the week if the player runs out of electricity, at which time the player will be greeted by his illuminated face, and the Toreador March before being attacked. From the 3rd night onward, he will become active. When Freddy starts to move, a deep laugh is heard instead of footsteps. Freddy only moves when the cameras are down. Freddy can only enter The Office via the Bathroom.
|Farthington the Knight
|Throne Room
Farthington works as a knight protecting the princess, stays with his brother at the stage, until it's time to move. His ability is to slowly walk to the Office at a slow pace (you can hear his loud armour footsteps) towards you. His weakness is to be spotted, in which he will be still until a couple seconds after you stopped looking at him. If he reaches your area, it's Game Over. The doors will bust open, and he'll get you.
|Sami the Squire
|Throne Room
Sami will stay at the stage, only moving when Farthington moves. Sami will move alongside him but will not follow if Farthington tries to help Penny. Sami will instead sprint around them and straight for the office. You must quickly shut the doors before he manages to make it to the Office.
|Bonnie the Villager
|The Garden
Bonnie is known for returning to The Office more frequently than the other animatronics, and he only approaches from the left side. He will stare through the doorway into The Office, unlike Chica, who looks through the window. Bonnie also has a special ability in which he can disable the cameras temporarily as he moves to another area, as does Chica.
|Chica the Cook
Chica will generally head towards the player's position, similar to Bonnie, but she also wanders to the Kitchen and Chapel. As opposed to Bonnie, Chica will show up at the door less often, but will generally linger there, waiting longer and stealing more of the player's energy, whereas Bonnie will show up often but leave quickly.
|Joaquin the Jester
|Jester's Prison
Joaquin goes a set distance towards your right side, and decides to be sneaky, trying to avoid the sight of the camera. If he reaches the right side, he will drain your power faster, thus making it harder to survive. The only way to prevent that is for you to click on him in his location during his sneaking, which will scare him off back to the Jester's Prison. If he's at your right side, you have to use the light to spot him.
|Penny the Princess
|Princess' Chambers
She wanders the facility, galloping and playing around wherever she goes. You can tell where she goes by a light that will enter in from a certain part, and the rising volume of her singing. When you look directly at her with your camera, she will scream very loud, which causes Farthington to run over to her. The Knight will ignore being seen, and will rush over to the Princess's location. If the Jester sees the Princess, the Knight will attack him, and stun him for a longer time than being spotted.
|Matt the Monkey
|Dining Room
A small brown monkey wearing a red fez and vest. It has a wide creepy light up grin and plays a organ grinder. Matt doesn't kill the player instead jumping in front of the camera, flinging something at it, disabling it for some time. He also jams the door with Bananas if you're not watching and you will have to clean it quickly. But the worse thing is he can sprint in and mess with the lights and doors, draining your power then running out. Matt is too fast to watch on camera so you must listen for his organ music. Once it is really loud, shut the door and you'll hear a bang as if he smacked into the door and he'll be knocked unconscious for the rest of the night.
|Ethan the Executioner
|The Dungeon
Unlike the other animatronics, Ethan will be seen swinging his axe around in the Dungeon instead of staying still. He will continue to swing his axe while advancing towards the player. When Ethan is moving, you will hear the sound of an axe being dragged across the ground. When he reaches the Office, you must close the doors immediately. However, there is a 1 in 100 chance that he will break the door open with his axe. Instead of the usual jumpscare, he will be seen standing in front of you. Two seconds later, he will swing his axe, resulting in a Game Over.
|Fabian the Fish
|Security Office
Fabian is located through a glass ceiling panel in the Office. You can view him through a camera in his tank. The tank begins each night totally full, but has a leak. The tank slowly runs out of water, and the fish (which floats) slowly approaches the panel above the player. Once the fish reaches the panel, it rams into it 3 times. Each time it rams, there's a loud noise. The fish also cracks the glass more each time it rams, and after the third time, it stares at you, screams, and launches through the panel (killing the player).
The only way to stop the fish is to add water (which you have a limited supply of, like power) to the tank, causing him to float back up. Also, each time you fill the tank, it takes 5 seconds or so of helplessness while you turn the nozzle.
Freddy Fazbear's Pizza
|Show Stage
The Show Stage is occupied by Bonnie, Chica, and Freddy Fazbear.
Bonnie and Chica are the first to leave the stage, with Bonnie being the first in earlier nights. Freddy and Perry, however, will not leave the stage until The 3rd Night. Also, on any night, Freddy and Perry can stare into the camera while on the show stage, albeit quite rarely.
|Pirate Cove
The Pirate Cove is occupied by Foxy only. Foxy operates using a different mechanic than the other animatronics: if the player checks the camera for this area too much or too little, Foxy will slowly emerge from behind the curtain and sprint to the office, giving the player a few short seconds to close the left door before he attacks.
|Kid's Cove
The Kid's Cove is occupied by Mangle only. The Mangle can be seen laying on the ground - broken, battered, and basically destroyed. It was destroyed by the children playing there, as pictures on the wall depict kids kicking him and holding his torn-off head. There is also a poster to the far right (almost barely visible) that seems to say 'The new face of playtime' with the Mangle's face on it. Using the poster can determine how the Mangle's facial area looked before it fell into disrepair.
|The Attic
The Attic is occupied by Larry the Lion only. Larry can be seen staring straight at the camera, with his blood-stained mane and eyeless face. Sometimes, Larry can be seen twitching around with the camera shutting off three seconds later.
|The Basement
The Basement is occupied by Terry the Tiger only. Terry can be seen looking away from the camera, with his blood-stained fur and cut neck. Sometimes, Terry can be seen twitching around with the camera shutting off three seconds later.
|Game Area
The Game Area is occupied by Balloon Boy only. The animals on the carousel are the same as the Fazbear gang: a bunny, a chicken, a fox, and a bear.
|Prize Corner
The Prize Corner is occupied by The Puppet only. While viewing the Prize Corner on your monitor, there is a button labelked "Wind up Music Box", and directly below the button says "Click and Hold." Winding up the Music Box keeps the Puppet from moving. There is a timer next to the button that shows how much time is left before the player must wind up the Music Box again before the Puppet starts moving. At some points, when using the Flashlight during the red caution sign, the Puppet appears on the stand to the right, which suggests that he lifted from the box, as seen in the drawn pictures on the wall.
The Parts/Services will be occupied by Marty the Mammoth when repaired.
|West Hall
The West Hall is not occupied by any animatronic. The West Hall consists of the West Hallway, West Hallway Corner & the Left Air Vent.
|East Hall
The East Hall is not occupied by any animatronic. The East Hall consists of the East Hallway, East Hallway Corner & the Right Air Vent.
The Hallway is not occupied by any animatronic. The Hallway is located in front of the Security Office. You are able to use your Flashlight to view the Hallway while off-camera. You are also able to view the Hallway with your camera.
|Security Office
The Office is occupied by the player.
There are Doors and a Grate to cover the vents. Animatronics can enter through the doors or vents. The player can not move and can only switch his gaze from left to right and vice versa.
Freddy Fazbear's Castle
|Throne Room
The Throne Room is occupied by Freddy, Farthington and Sami. Freddy will be seen sitting on his throne, with Farthington and Sami kneeling beside him. Freddy will always move first, unless the Princess is seen before he can move.
|The Garden
The Garden is occupied by Bonnie. Bonnie will be seen, surrounded by limp flowers, dead butterflies and fallen tress. Bonnie will sometimes stare at the camera.
The Kitchen is occupied by Chica.Chica will be seen in this location, surrounded by frying pans, bread rolls and cooked chickens. Chica will sometimes stare at the camera.
|Jester's Prison
The Jester's Prison is occupied by Joaquin. Joaquin will be seen, surrounded by rusty chains, iron bars, a mace and blood stained floor. Joaquin will sometimes switch the camera upside down.
|Dining Room
The Dining Room is occupied by Matt. Matt will be seen, surrounded by chandeliers, fireplaces and bananas. The chairs are fallen and have banana peels covering them.
|The Dungeon
The Dungeon is occupied by Ethan. Ethan will be seen, surrounded by a guilotine, axes and a blade. The room is blood-stained.
|Princess' Chambers
The Princess' Chambers is occupied by Penny. Penny will move five seconds after the Night starts, never coming back into this room. This room is actually quite beautiful with a unicorn doll and floral wallpaper.
The Bathroom is not occupied by any animatronic. The Bathroom features a toilet, bathtub and a sink. The bathtub is filled with water and sometimes will be filled with blood or jewellery.
|The Chapel
The Chapel is not occupied by any animatronic. The Chapel features statues of Jesus Christ and a Holy Cross in the middle of the room. A chandelier hangs over it.
|Security Office
The Office is occupied by the player.
There are Doors and a Grate to cover the vents. Animatronics can enter through the doors or vents. The player can not move and can only switch his gaze from left to right and vice versa. Fabian is located above the player and must be checked on from time to time.
- Dec, 11, 2014: Teaser for TNaF with a picture of Freddy's face with a "3" next to it.
- Jan, 12, 2015: An image of the Pizzeria and the Castle alongside it. Empty blocks around it named "under construction".
- Jan, 19, 2015: Freddy Fazbear's Castle confirmed in TNaF. Also ten nights confirmed.
- Jan, 25, 2015: Images showing inside the Pizzeria and Castle.
- Feb, 1, 2015: Image showing a shadowed animatronic holding a bloodied axe with a caption, "You're next."
- Feb, 13, 2015: Trailer revealed showing the new animatronics, rooms and other things.
- Feb, 25, 2015: Demo and paid version released on Steam, Google Play and the App Store by Scott Cawthon.
- The shadow seen by Kenny has been speculated to have been many things. However, three have been the most popular
- It is believed to be a hallucination due to the trauma that may have occurred to Kenny during his working period.
- It is also believed to have been something of supernatural formation. It is widely speculated to have been the Marionette, who sometimes appears in hallucinations in the Left Vent, laughing maniacally at the player. It is believed that the Marionette is real.
- It is also believed that the shadow may have been the lights being destroyed as no lights are activated in the end.
- Many people asked questions about the ending such as why Kenny did not get fired for tampering. One of the developers, NovaPen, explained that Kenny had fled before he had been fired.
Easter Eggs
The Marionette
On some nights, a Marionette is seen in the Left Vent. This is a very rare occasion and seems to occur at random intervals.
Easter Easter Egg
During the Easter holidays, Bonnie will wear an Easter Bunny costume.
Christmas Easter Egg
On December 25th, the Music Box will play Jingle Bells instead of My Grandfather's Clock.


text:
Weather Web resources for teachers, kids and parents -- including lesson plans
Internet is a gold mine for teachers and parents alike who wish to give kids an
early start on learning about the weather.
We've compiled a few online resources that will help kids learn about
weather. Most are geared toward elementary and middle school
kids, but there's some for the high school level near the bottom.
Nick Walker's 'Weather Dude'
Web Site
Wicker's Weather Wiz Kids Site
Learn About Weather Instruments
Weather Unit from Univ. of Illinois
Kids Guide to El Nino
Here And There Lesson Plans
Weather Using Weather Maps Lesson
Weather Terminology Page
KOMO's "How Do I Become A Meteorologist?" Page
Google Search For More Lesson Plans
And, of course, you can e-mail us at
email@example.com with any
specific weather questions you might have.


text:
Paper Archives
19. June 2013
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Tampa Bay Buccaneers
Bucs rookie Foster makes big impact in victory
TAMPA - Tampa Bay Buccaneers rookie middle linebacker Mason Foster capitalized on a teammate's injury to make a major impact in Sunday's victory at Minnesota. With outside linebacker Quincy Black sidelined by an ankle injury, Foster registered a team-high 10 tackles in his second game as a pro, adding a sack, a quarterback hit, a tackle for a loss and a forced fumble as Tampa Bay rallied for a 24-20 triumph. "He was stout,'' Coach Raheem Morris said of the third-round pick out of Washington. "He played with energy. Of course, he had a couple of mistakes, kind of like my whole football team, but his understanding of those mistakes and ability to correct them shows his growth and development.'' Foster played sparingly in the season opener against Detroit but was used extensively on third down Sunday with Black hobbled."I felt like I got better,'' Foster said Monday. "I still had some mistakes I shouldn't make, but at the same time I'm learning. The NFL's a physical league, and it felt good to be out there with the game on the line.'' The extent of Black's injury was not known Monday. Morris hopes to know more by Wednesday when the team begins preparation for Sunday's home game against NFC South rival Atlanta.
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$1,399,000 - SF w/Det Ohana or Cottage
Once you enter this private half acre estate you come upon the circular driveway which wraps around an awesome gazebo, which has its own sound system and surrounded by colorful bougainvillea. Cross the entry bridge over the 9000 gal. pond which used to have Koi and other colorful fish. The Pond has been recently re-finished and ready for whatever you may want to do with it. As you enter this home with 10 foot ceilings, 5 bedrooms (3 of which are Master Suites), 4.5 baths you immediately see the quality of workmanship starting with the marble floors, the frosted sky light, the sunken dining room with contrasting marble floors and the entertaining aquarium sized view of the pond. There is granite tile in the kitchen, open natural wood beam ceilings, imperial plaster walls, complete security system, sound system plus the whole house has a fire sprinkler protection system and fire rated doors through-out. There are beautiful Ocean Views and sunsets from the Upper level lanais. Walk in closets, mirrored sliders, oversized rooms, hand carved etched glass built-ins with back ground lights make this a must See. The detached 696 s.f. 1/1 Guest Cottage is private and equally well constructed. There is also another full bath in the pool room building area and next to the workshop. The nicely maintained spacious grounds allow for gardening and even a pool. There are various fruit trees around the property. This could be a great property for a bed and breakfast,Co having the three Master Suites and the separate private cottage.


text:
Reuters Staff
1 Min Read
Dec 13 (Reuters) - Actinium Pharmaceuticals Inc
* Actinium Pharmaceuticals announces submission of EU Orphan Designation application for Actimab-A Source text for Eikon: Further company coverage:
All quotes delayed a minimum of 15 minutes. See here for a complete list of exchanges and delays.
© 2017 Reuters. All Rights Reserved.


text:
Economy & Jobs
Energy & Environment
Global Europe
The European Central Bank must stick to its price stability mandate and not be swayed by politics, Germany's top central banker said Friday (16 December), warning against extending loose monetary policy for too long.
The UK's decision to leave is being felt on the other side of the Channel; the German economy has been hit by the result as well, the president of Germany's central bank told EURACTIV's partner WirtschaftsWoche.
Germany, Europe's biggest economy, shaved €24 billion off its overall public debt burden to €2.153 trillion in 2015, the Bundesbank said on Thursday (31 March).
Germany needs to send a message to the world that it is reaching the limit of its capacity to help Europe's flood of migrants, German Finance Minister Wolfgang Schäuble said on Sunday - while the head of the Bundesbank said the country can handle the costs of the refugee crisis without risking its balanced budget.
A complaint filed against the European Central Bank over its unlimited bond-buying programme known as OMT was up for debate in the European Court of Justice on Tuesday (14 October), with German Eurosceptic complainants issuing harsh criticism of the ECB's strategy to combat the debt crisis. EURACTIV Germany reports.
European Employment Commissioner Laszlo Andor said wages in Germany were not climbing sharply enough and the government should ensure that salaries increased in line with productivity.
Rebuffing criticism in Germany that Rome is too slow to reform, Italian prime minister Matteo Renzi on Friday (4 July) reasserted that he is ready to stand up to critics and reclaim a leadership role in Europe.
The European Central Bank could buy loans and other assets from banks to help support the eurozone economy, Germany's Bundesbank said Tuesday, marking a radical softening of its stance on the contested policy.
The European Parliament approved today (16 January) Sabine Lautenschlarger for the vacant seat on the European Central Bank's board. The German candidate has called for regulation on the planned pan-European bank wind-up agency would come into force earlier than 2018, EURACTIV Germany reports.
The European Central Bank and the German Bundesbank have warned that businesses are stalling on updating their payment systems in preparation for the switchover to the new EU-wide transfer and direct debit procedure, the Single Euro Payments Area (Sepa). EURACTIV Germany reports.
The vice president of Germany's Bundesbank on Monday (10 June) called for an effective Europe-wide bank resolution authority, a position at odds with the German government which has been resistant to such a move.
The European Central Bank agreed yesterday (6 September) to launch a new and potentially unlimited bond-buying programme to lower struggling eurozone countries' borrowing costs and draw a line under the debt crisis.
This is the man who claimed he can save the euro. After weeks of uncertainty, European Central Bank's chief Mario Draghi on Thursday unveiled a much-awaited bond-buying plan. The scheme includes buying 'unlimited' amounts of short-term government debt from troubled countries and it is designed to lower the borrowing costs of Italy and Spain. Draghi also said the scheme was a "fully effective backstop" and that the euro was "irreversible".
European Central Bank chief Mario Draghi faces the most decisive moment of his presidency today (6 September) when he tries to heal divisions among policymakers and deliver on his promise to save the euro. A leaked draft reveals that the plan includes buying 'unlimited' quantities of government debt from troubled countries.
Commissioner for the Single Market Michel Barnier is expected to bring forward changes to his market abuse directive and regulation within the coming weeks, the Financial Times said Monday.
The euro area has been close to collapse at least three times in the last four years. However the 'strategy of uncertainty,' theorised primarily by the German government and Central Bank to fend off the crisis, is ill-conceived and it is high time to have strategic certainty, writes Carlo Bastasin.
According to insiders, Italian Mario Draghi, on track to become the new European Central Bank chief having received the backing of eurozone finance ministers, will need to dispel mutterings about lax southern Europeans and win over a more hawkish Bundesbank chief.
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text:
Editorial: Arthroplasty devices: Registries and beyond.
In spite of the overall technological progress and clinical success of orthopaedic devices, unexpected safety concerns, such as those reported for some metal-on-metal (MoM) total hip replacements [2], continue to attract substantial attention from patients, physicians, and policy makers. Recently, CORR ®'s Editor-in-Chief suggested that it can be "difficult to resist the lure of new technologies." [3]. Indeed, the current healthcare environment in the United States is such that the early adoption of new technologies may be difficult to resist, and introducing new devices into a complicated biological milieu like the human body will always be complicated and, to some degree, uncertain.
Established international registries such as those implemented in Australia [1], as well as in England and Wales [4], effectively monitor both the successes and the problems associated with newly introduced implants. Similarly, the establishment of the International Consortium of Orthopedic Registries, consisting of 29 international registries with information covering more than 3.6 million orthopaedic implants, represents an unprecedented effort to collate this information into an even more effective resource. In the United States, the FDA is working on advances that will more effectively employ registries to better understand in vivo device performance [7]. Certainly, the current and developing orthopaedic registries in the United States are becoming a valuable resource containing clinical documentation about the performance of specific devices and technologies in definable patient populations. However, recent recalls related to certain MoM hip implants [9] suggest there are important limitations associated with the current approaches to arthroplasty-related data gathering and analysis. While registries record some information – for example, they distinguish between aseptic loosening and loosening from infection – they generally are silent on the mechanisms of failure beyond that. And as we have seen recently, particularly with the MoM failures, we must come to understand these mechanisms. Inconsistent and confusing terminology further frustrates our efforts; for example, soft-tissue changes in response to metal interactions may be described using a variety of terms, including "metallosis", "pseudotumors", "adverse local tissue reaction", "aseptic lymphocyte-dominated vasculitis-associated lesion", and "adverse reaction to metal debris".
There is a clinical and regulatory need, but also an unprecedented opportunity, for further development of national and international initiatives aimed at capturing and synthesizing interdisciplinary (clinical, biological, technological) evidence for more comprehensive analysis of the causes pertaining to orthopaedic revision burden. Along with the US national registries, the FDA is a key partner in this multidisciplinary effort. The FDA's Center for Devices and Radiological Health (CDRH), where two of the authors work (YT, DM-D), has taken on this challenge, consistent with the CDRH goals of facilitating medical device innovation through the advancement of regulatory science and providing our industry with reliable and efficient regulatory pathways [6].
To expand the evidentiary capabilities provided by registries, we need further evidence on device performance that incorporates higher-level data derived from in vitro biocompatibility testing, radiographic monitoring, and appropriate explant and periprosthetic tissue analysis.
Explant retrieval analysis, for example, remains one of the most-important sources of ex vivo evidence that can support a deeper understanding of the safety and effectiveness of established implant technologies and delineate the steps to minimize possible failure. Meta-analyses that characterize both the extent of device alterations (physical, mechanical, chemical), as well as the extent of the biological response (eg, periprosthetic tissue necrosis and inflammation), are necessary to understand in a comprehensive way the factors that determine an implant's clinical success or failure. However, registries cannot provide this information, which is so necessary to understand fully the in vivo success and failure patterns of today's arthroplasty devices.
Evidence synthesis from a variety of sources into a robust clinical and regulatory framework could allow innovation to occur in such a way that genuine improvements can be delivered to patients, while protecting patients from unintended and sometimes severe consequences. As one part of the solution to address the evidentiary challenges and needs, the CDRH is developing revised guidance documents on the use of biomaterials- and device-related standards and clinical outcomes with input from the clinical, research, and industrial communities. For example, the CDRH is currently working on a scientifically-validated Medical Device Development Tools program [8] that can incorporate clinical outcomes, marker-based tests, analytic assays, imaging methods, and nonclinical assessments based on predictive modeling. Taken together, these approaches seek to advance the assessment of medical devices, including joint replacements. This ideally will be achieved in a manner that does not result in increased cost or delays in introducing new technology or which could lead to other industry disincentives due to over-regulation.
How can the orthopaedic community participate in this effort? For these new approaches to be successful, the US registry movement needs to be broadly implemented by hospitals across the country. Well-functioning registries are fundamental to the goals of the orthopaedic community [5]. However, we also need new partnerships and an integrated infrastructure to enable the successful incorporation of clinical and imaging data and the results of biocompatibility testing and retrieval analysis into a more comprehensive process of implant evaluation. Presently, numerous legal and regulatory challenges impede the establishment of such multi-institutional orthopaedic efforts. For example, hospitals discard most retrieved tissues and devices collected at revision surgery after routine pathological examination. The orthopaedic community can support regional and national orthopaedic registries by directly supporting device and tissue retrieval and analysis as well as by participating in other registry-based research efforts. By extension, researchers need to make their findings accessible by creating shared data sources and discussing their clinical applicability at orthopaedic forums so that their data can be readily available to and actionable by the surgeons and wider orthopaedic community.
Ultimately, research data for explanted devices and tissues need to be directly linked to the device/patient records in national registries. Such registry-based networks will serve as the basis for a new evidence-gathering approach, which begins with implant design, and continues to track device performance throughout its lifetime or the lifetime of the patient. As a result, better designed epidemiological studies will be enabled by translational research findings and will be performed via well-functioning national registries linked to complementary sources of multidisciplinary evidence.
1. Australian Orthopaedic Association National Joint Replacement Registry. Annual Report. 2013. Available at: http://www.dmac.adelaide.edu.au/aoanjrr/publications.jsp. Accessed October 17, 2014.
2. Langton DJ, Jameson SS, Joyce TJ, Gandhi JN, Sidaginamale R, Mereddy P, Lord J, Nargol AV. Accelerating failure rate of the ASR total hip replacement. J Bone Joint Surg Br. 2011;93:1011–1016.PubMedCrossRef
3. Leopold SS. Editorial: Our love affair with technology and the choices we make. Clin Orthop Relat Res. 2014;472:2907–2908.PubMedCrossRef
4. National Joint Registry. The 10th annual report of the National Joint Registry for England, Wales and Northern Ireland. 2013. Available at: http:// www.njrcentre.org.uk/njrcentre/AbouttheNJR/Publicationsandr eports/Annualreports/Archivedannualreports/tabid/87/Default.aspx. Accessed October 17, 2014.
5. Sedrakyan A, Paxton EW, Marinac-Dabic D. Stages and tools for multinational collaboration: the perspective from the coordinating center of the International Consortium of Orthopaedic Registries (ICOR). J Bone Joint Surg Am. 2011;93 Suppl 3:76–80.PubMed
6. United States Food and Drug Administration. About the center for devices and radiological health. Available at: http://www.fda.gov/AboutFDA/CentersOffices/OfficeofMedicalProductsandTobacco/CDRH/. Accessed September 6, 2014.
7. United States Food and Drug Administration, Center for Devices and Radiological Health. Strengthening our national system for medical device postmarket surveillance; Update and next steps. April 2013. Available at: http://www.fda.gov/downloads/MedicalDevices/Safety/CDRHPostmarketSurveillance/UCM348845.pdf; Accessed Sep 15, 2014.
8. United States Food and Drug Administration. Medical device development tools. Available at: http://www.fda.gov/MedicalDevices/ScienceandResearch/MedicalDeviceDevelopmentToolsMDDT/default.html. Accessed October 17, 2014.
9. United States Food and Drug Administration. Recalls specific to metal-on-metal hip implants. http:// www.fda.gov/medicaldevices/productsandmedicalprocedures/ implantsandprosthetics/metalonmetalhipimplants/ucm241770.htm. 2014; Accessed September 6, 2014.


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The third Black Eyed Peas [1] single from "The E.N.D." is somewhat of a departure from previous hits "Boom Boom Pow" and "I Gotta Feeling," which collectively spent a record-breaking 26 weeks atop the Billboard Hot 100. While the Peas' circa-3008 production aesthetic is still at the forefront, "Meet Me Halfway" boasts a slightly breezier, more downtempo beat and a vintage Madonna [2]-inspired chorus: "Can you meet me halfway/Right at the borderline/Is where I'm gonna wait for you." Fergie [3] elongates each note for a sensual vocal and offers a nice complement to co-producer Will.i.am [4], who handles the majority of the rhymes over funk guitar, hand claps and distorted pulses. Already climbing the Hot 100 with their latest, the Peas are evidently on a quest to prove that their hit parade is far from over. -Michael Menachem
- Track Review [5]


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Im Leaving S&S
Discussion in 'Slim And Save' started by X Kelly X, 7 September 2011 Social URL.
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Look! Chicago in Flux
We've been feeling a ridiculous amount of pride for our city lately. Part of it is induced by the euphoria that happens to most Chicagoans during our brief but beautiful summer, but lately it's been more than that. After reading the Alex Kotlowitz article about Chicago that Heather posted, we've been thinking about what Kotlowitz describes as "Chicago's lure and its beauty: its ability to take what was and figure out what could be..."
Chicago is not without its problems. We've bemoaned the city's ineffective recycling program, and although we have some cool new public housing projects we also have a serious shortage of subsidized housing for those who need it. Kotlowitz knows Chicago's problems well - his most famous book, There Are No Children Here, makes the problems with Chicago public housing very real and present.
Still, despite the city's problems, there is a sense of life that feels like it's reaching a fever pitch right now. Yesterday we found out that Chicago has been short-listed for the 2016 Olympics, and this week our Senator from Hyde Park, Barack Obama, secured the Democratic Nomination for the Presidency. Chicago is in flux, and whether or not we like the direction things are going, we're in the middle of an exciting moment.
We're very lucky to have a job that allows us to write about living in this city. Our schedule is such that we work from home in the mornings and go downtown in the afternoons for our second job. Every day, our route from the bus takes us through some of Chicago's most spectacular spots, and we get to see the city moving, breathing, and changing.
Sometimes we take a moment just to look, although we've seen these places hundreds of times before. Chicago has some of the world's best modern architecture (okay, maybe not the Trump Tower...but at least it's not gold). It's hard not to feel some sort of awe when you're walking across the Chicago River. Everything around you seems monumental in scale and very much alive.


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Latest Stories
Shrek SuperSlam Update0 Comments
October 13, 2005
Help us solve the toughest (or most puzzling) game puzzles and challenges.
Our attempt to answer issues which most commonly occur on IGN's wikis.
About This Game
- Summary
- Specifications
- Game Editions
Shrek SuperSlam is a four-player melee fighting game set in 3D fully destructible environments that parody legendary fairytales and popular culture. Gamers play as 20 favorite Shrek and fairytale characters, unleashing power slams, taunts and signature attacks including juggling foes as Donkey, swashbuckling as Puss in Boots, leveling kung fu kicks as Princess Fiona and belly flopping as Shrek. Players use powerful potions, weapons and magical items and unlock new characters, arenas and costumes in single player story, ladder and mega challenge modes, or engage in frenzied multiplayer melee combat.
- Supported Functions
- Number Of Players: 1
- Memory Card
Shrek SuperSlamPublisher: ActivisionRelease Date: October 25, 2005MSRP: 19.99 USD


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Doctors for Disaster Preparedness
| Not just a river in Egypt
|♫ We're not listening ♫
Doctors for Disaster Preparedness (DDP)[1] is a somewhat curious denialist group associated with anti-environmental forms of denialism (including DDT ban myths, ozone depletion denial, global warming denial, and crank theories about radiation hormesis) and medical denialism (vaccine denial and HIV denial).
They are associated with Arthur B. Robinson's Oregon Institute for Science and Medicine, which distributes the Oregon Petition with its highly dubious claim to have identified 31,072 scientists who oppose the anthropogenic global warming consensus. DDP also seems to be another outlet for Robinson's brand of survivalism, being more concerned about the specter of nuclear war and duck and cover drills than actual problems or disasters. Their mission is, in theory, to refute "fake" threats and help prepare for "real" ones. Thus, the possibility of global thermonuclear warfare, vaccines, environmentalists, and dirty hippies — big threats to the existence of society. Global warming, ozone depletion, AIDS, etc.? Not so much. Their "educational resources" also include links to such trustworthy sites as Junk Science and the Heartland Institute.
Their address at 1601 N. Tucson Blvd. Suite 9, Tucson, Arizona is shared with that of the Association of American Physicians and Surgeons (and a pile of other charities), for whom Andrew Schlafly is general counsel. Andrew Schlafly was also a featured speaker at Doctors for Disaster Preparedness' July 2008 annual conference, where he spoke on "The Education of the World's Great Thinkers".[2] If you must, an mp3 of the speech is on archive.org.
DDP also gives out an award called "The Petr Beckmann award for courage and achievement in defense of scientific truth and freedom." It has been awarded to such denialist luminaries as:
- Marc Morano (2010)[3]
- S. Fred Singer (2007)[4]
- Willie Soon (2004)[5]
- Sherwood Idso (2003)[6]
- Sallie Baliunas (1997)[7]
- Arthur Robinson (1998)[8]
- Jane Orient (1995)[9]
See also[edit]
External links[edit]
- ↑ More accurately, "Doctors for Disaster Denial"
- ↑ Schlafly teaches worlds greatest thinkers shock!
- ↑ 2010 Beckmann award given to Marc Morano
- ↑ 2010 speaker bios
- ↑ 2010 speaker bios
- ↑ On accepting an award.
- ↑ Sallie Baliunas receives Beckmann award
- ↑ 2002 DDP speaker bios
- ↑ DDP Newsletter. She is also the president of DDP, an adviser to the OISM, and an executive director of AAPS, so no conflict of interest there.


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I have been extremely impressed by this place. The staff uses little fancy equiptment, but can provide routines and exercises tailored to any level of fitness. I started overweigh...
All reviews seem positive
Specializing in personal training and fitness instruction at reasonable rates.
From family friendly trips with kid friendly activities to local plumbers lawyers, spas, and contractors. Judy's Book has millions of listings and reviews for the best and not so great. Whether you're looking for a specific business or just trying to discover great places we make it easy. We're a family oriented site focusing on bringing trusted reviews and recommendations to moms and others. Green and Sustainable places are becoming more relevant to Judy's Book users, have a favorite place? Write a review and tell users why it's Green!


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I've been going to Dubai for ten years almost monthly and used to stay in a different hotel until it changed management and subsequently all the staff too, I chose Raffles because of its excellent location in the centre of the city close to the airport. I was blown away with my first stay. From then on I knew that I would stay at Raffles forever when I come to Dubai.
The staff here have outperformed every other hotel I have ever stayed in across 45 different countries. The biggest difference is that they listen to their guests and remember. I couldn't believe how they would remember my coffee or fruit preferences and pick up on subtle things I said about what I liked and didn't like. This hotel is at the cutting edge of hospitality down to the carefully selected and highly trained staff.
Of course behind the amazing staff is a wonderful hotel with no expense spared in the decor and facilities, some of the largest rooms in Dubai and a certain decadence that new hotels totally lack.
Raffles Dubai is one very impressive package that is exemplary in a city with such strong hotel competition. But someone has to be number one and the staff here wanted it more than any where else which is evident in their sincere hard work.
A stay here will be more than memorable.
- Official Description (provided by the hotel):
- A stunning landmark hotel in a distinctive pyramid shape merges Asian style with an Egyptian aesthetic. Ideally located in the city center with a shopping adventure lies around the corner as Raffles Dubai adjoins Wafi mall, one of Dubai's most exclusive shopping and leisure destinations, home to hundreds of boutiques offering an extensive selection of international haute couture, jewelries and gifts in addition to nearby authentic souks, including the impressive Khan Murjan, offering traditional crafts by artisans from the region. Featuring 252 luxurious rooms and suites, this award-winning Dubai hotel offers some of the most spacious rooms in the city, each with generously-sized private balconies. Brilliant contemporary interiors, faultless service and 7 superb restaurants and bars offering an extensive array of dining, entertainment and clubbing options, while Raffles Spa beckons with a pampering menu to emerge transformed, like a lotus that journey from bud to the radiance of full bloom. ... more less
- Reservation Options:
- TripAdvisor is proud to partner with Booking.com, Fairmont Hotels, Expedia, Travelocity, Asiatravel.com Holdings, Ctrip TA, Splitty, Hotels.com, Cancelon, Hotwire, TripOnline SA, Orbitz, Evoline ltd, getaroom.com, HotelQuickly and Cheap Tickets so you can book your Raffles Dubai reservations with confidence. We help millions of travelers each month to find the perfect hotel for both vacation and business trips, always with the best discounts and special offers.
- Also Known As:
- Raffles Dubai Hotel Dubai
- Raffles Hotel Dubai
- Dubai Raffles Hotel


text: In my 2001 fiat palio 1.6GTX after starting the vehicle my wipers, airconditioning, electrical windows, lighter, and head lights seize to operate. I checked all fuses next to the steering wheel. The problem persist. Sometimes the problem continues for about twenty minutes whilst driving then everything is working for a little while then back to problem stage. Fuel injector icon is also flashing Can any one advice please advice?


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Many people suffer from weight management problems. If you are the type who simply cannot say no to any food, this can be a problem. Not only will you end up gaining weight and become obese, your colon is also at risk. The colon is a vital organ in the body responsible in eliminating dirt and toxins. Eating too much oily and fatty food will definitely damage your health.
For sure, you have come across many products in the market saying that they can help you cleanse your colon. Among them is the QuickTrim Cleanse product. The aim of this review is to present the pros and the cons along with the other details that consumers need to know before they finally buy the product.
QuickTrim Cleanse Product Details
The QuickTrim Cleanse Product works in two ways. For one, it aims to cleanse your colon. Through body detoxification, it is said that you will eventually lose weight. As such, this product has become widely popular not just for those seriously want to address their colon related concerns and digestive issues but as well as those who want to lose weight. The product dubbed itself as the rapid weight loss formula. Just by using this supplement, you can already cleanse and detoxify your colon while at the same time jumpstart their weight loss and achieve their long term health goals.
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Does QuickTrim Work?
Considering the nature of the product and the benefits it claims to give, many want to know if this product really works. When you search for online reviews, the opinion is quite divided. Some online users who have already tried the product say that they're able to get the results that they want. On the other hand, there are some who appear not to satisfied with QuickTrim Cleanse.
Advantages and Disadvantages
To help consumers weigh their options, this review presents the advantages and disadvantages of using QuickTrim Cleanse.
- The product works not just as a colon cleansing product but also as a weight loss formula.
- It boosts energy levels.
- It suppresses your appetite.
- The product is very easy to use.
- Highly nutritional.
- Makes use of natural ingredients.
- Safe to use.
- It goes down easy.
- The product is also proven effective in colon detoxification as well as weight loss.
- Many consumers complained about the taste. They say the product has a bad flavor.
- Bad taste.
- Some think that it is not that effective.
Customer Reviews
One of the reasons why QuickTrim Cleanse is really popular in the market is that Hollywood artists say that they use the product and are able to get good results. But when you search for online reviews, you will find not everyone is completely satisfied with QuickTrim Cleanse. There are customers who say that this product works well as it definitely helped them lose weight and cleanse their colon. However, there are also some who think that the product is not worth it.
Final Verdict
If you are just in search for a supplement that works not just as a colon cleansing product but also as an effective weight loss formulate, you can definitely try the QuickTrim Cleanse product. However, you should also keep in mind that this is not a miracle product. If you want to get good results like for instance if you are really serious about losing weight, you need to use this product and at the same time, you need to have good diet and exercise.