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3x2 Organize-It Set, Rustic Wood
- Overview
With our wall organizer, everything just seems to fall into place. There's a spot to stow your iPad, caddies for pencils and homework, a bin to corral wayward items, hooks for hanging, a dry-erase calendar for important dates, strips for posting pics and notes, and a chalkboard and dry-erase board for doodling or jotting notes.
- 60" wide x 29" high
- Set includes one double frame, one single frame, two dry-erase boards, one pencil caddy, one homework caddy, one dry-erase calendar, one multibin caddy, one chalkboard, one iPad caddy, one magnetic strip, one cork strip and one hook strip.
- Crafted of catalpa wood, MDF and metal boards.
- Each item can either slide or hang onto the frame for a unique and customizable look.
- Mounting hardware included.
- Dimensions + Care
- Overall: 60" wide x 29" high
- Single Frame: 20" wide x 14" high
- Double Frame: 40" wide x 29" high
- Dry-erase Board: 20" wide x 13" high
- Pencil Caddy: 10" wide x 12" high
- Homework Caddy: 10" wide x 12" high
- Dry-erase Calendar: 20" wide x 13" high
- Multibin Caddy: 20" wide x 12.5" high
- Chalkboard: 20" wide x 13" high
- iPad Caddy: 10" wide x 12" high
- Hook Strip: 20" wide x 2.5" high
- Cork Strip: 20" wide x 2.5" high
- MDF is an engineered wood that lends exceptional strength and ensures structural integrity over time.
- Dust with a soft, dry cloth.
- Shipping & Returns
With Front Door Delivery, your item ships from our Distribution Center by UPS and arrives to your home within 4-5 business days of order receipt.
4-5 Business Days
Add $17.50 +
order by 6pm PT
Up to $15.00 $4.95 $22.45 $15.01–$25.00 $6.00 $23.50 $25.01–$45.00 $8.00 $25.50 $45.01–$65.00 $11.00 $28.50 $65.01–$90.00 $14.00 $31.50 $90.01–$125.00 $17.00 $34.50 $125.01–$200.00 $21.00 $38.50 $200.01 + over 10% 10% + $17.50 Gift Card only No charge $8.50
Add $6 for each gift wrap. For next day delivery, add $17.50 per address. Items shipped directly from the manufacturer and oversized items are not eligible for next day delivery.
For an extra charge of $17.50 per address, within the contiguous 48 states, we can arrange for next day delivery to most destinations. If we receive your order by 6pm PT Monday through Friday, you'll receive your order the next business day; orders placed on Friday after 6pm PT through Sunday will arrive on Tuesday. Note: Next day delivery service is not available for out-of-stock items, personalized items or for items shipped directly from the vendor.
Have more questions regarding shipping? Please visit our Shipping Information page.
Eligible items can be returned for a refund of the merchandise value within 30 days of receiving an order or 7 days for Quick Ship upholstery items. An original receipt or gift receipt is required.
How to Return
- Return to Stores - you can return non-furniture items to your local PBteen store for free.
- For non-custom furniture and other oversized items, call Customer Service at 866.472.4001
- Returns by UPS - print a return label from our Returns Policy page and bring to a UPS location.
Items Not Eligible for Returns
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Complete details
- See our full Returns Policy page


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Garinder Houlgate auction rooms has announced a number of guitars and amps from a number of iconic guitarists.
Up for auction on 15th June 2017 is a 1960 Magnatone amplifier (pictured), formerly owned and used in the studio by legendary Irish blues guitarist Rory Gallagher.
There will also be a 1969 Gibson Les Paul Standard electric guitar, formerly owned by legendary guitarist Greg Lake, up for grabs. The King Crimson frontman sadly passed away in December after a long battle with cancer.
A collection of guitars belonging to Mark Griffiths will also be up for auction on 15th June. Griffiths played guitar for Matthews' Southern Comfort who had the number one hit "Woodstock". The guitar used in the studio on this track is included.
Article continues below
All within the collection are a selection of bass guitars that Griffiths used live and in the studio with Cliff Richard, Hank Marvin, The Shadows and the Everly Brothers to name a few.
Check out the catalogue here and view the live saleroom here.
Garinder Houlgate auction rooms specialises in the sale of guitars and related items and over the last 10 years has established itself as the leading auction house for vintage and later guitars.
For more information visit www.gardinerhoulgate.co.uk and www.guitar-auctions.co.uk.

subset: commoncrawl


text: MOSCOW, June 17 (Reuters) - The Russian government started to tighten beer market regulation in 2010 by tripling excise taxes, followed by restrictions on sales, advertising and consumption, as part of a campaign to curb alcoholism. Here are some milestones that have changed the market landscape: 2010 Russia hikes beer taxes by 200 percent. 2011 Russian President Dmitry Medvedev signs a bill that classifies beer as an alcoholic drink. Most provisions of the law will come into effect in 2012 and 2013, extending to beer regulations that had already been applied to stronger spirits. Excise taxes rise by 11 percent. 2012 Russia bans beer drinking in public places and TV, Internet, and outdoor advertising of beer. Excise taxes rise by 20 percent. 2013 Russia bans beer sales in kiosks and other non-stationary places and bans beer sales elsewhere from 11 p.m. to 8 a.m., excluding bars, cafes and nightclubs. Regional authorities may set their own time limits and in some regions beer sales are now banned between 9 p.m. and 11 a.m. Beer advertising ban is extended to printed media. Excise taxes rise by 25 percent. Russian deputies call for an increase in the legal drinking age to 21 from 18. A bill is submitted to the State Duma lower house of parliament. Russian brewers agree to voluntarily stop selling beer in plastic bottles of more than 2.5 litres, or 2 litres for beer with an alcohol content above 6 percent, from 2014, amid calls from some parliamentarians to ban beer in plastic bottles completely. 2014 Excise taxes rise by a further 20 percent. The lower house of parliament takes the first step towards limiting the size of plastic beer bottles. (Reporting by Maria Kiselyova; Editing by Elizabeth Piper and Giles Elgood)


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Friday, September 28, 2012
Wednesday, September 26, 2012
Tuesday, September 25, 2012
Cool morning. Fresh thread.
Sunday, September 23, 2012
Sunday night thread. Jet lagged, but back in the USA.
Friday, September 14, 2012
Will be headed off to India today, so will be offline until late next week. Will post if I can get online.
In the meantime, here's a cool story for you.
In the meantime, here's a cool story for you.
Wednesday, September 12, 2012
Walking over to our commons building today I saw both of our eagles, soaring in circles high over the building.
New thread.
New thread.
Tuesday, September 11, 2012
Saw an adult up on the top of three at about 8:15 this AM.
New thread.
New thread.
Monday, September 10, 2012
New thread. Glad the pair was seen yesterday.
Saturday, September 08, 2012
Fresh thread.
Thursday, September 06, 2012
Tuesday, September 04, 2012
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Apologies for my neglect on this site. I'm thinking that it might be time to conclude this blog, as I started it before the social me...


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Sometime in April, we set off to this hotel to celebrate our honeymoon. We checked in and rested a while in the room, the upset started when we decided to take a stroll around the hotel trying figure out what the hotel had to offer. So, as we were walking around the hotel gardens and taking photos due to excitement, a security guard approached us and demanded to know who we were and why we were there! I have never been asked such a question by securities at a hotel before. So, right there, we demanded to know why was this guard asking us such questions and ordered to go ask his manager about us. Realising that we were not budging on the matter, he then stated that a white man who was a guest, sent him to confirm if we were not trespassing at the hotel.How insane! I realised that we were the only couple of colour in the vicinity. I believe that there are other ways to deal with guests who have a challenge seeing ppl of colour around them without having to offend guests!
We also noticed that the stafff at the pool bar and beach side would greet, give attention to the white guests and not bother to even greet us. All I can say is that, this hotel is beautiful but there are still very clear elements of racism and sadly even the black staff towards black guests. As a nonKenyan, I look forward to visiting this country and spend time at the beach but I dread the experience as I have to shout n scream before good service is offered.
- Reservation Options:
- TripAdvisor is proud to partner with Expedia, Booking.com, Travelocity, Cancelon, Hotwire, TripOnline SA, Orbitz, getaroom.com, HotelQuickly and Cheap Tickets so you can book your Diani Reef Beach Resort & Spa reservations with confidence. We help millions of travelers each month to find the perfect hotel for both vacation and business trips, always with the best discounts and special offers.
- Also Known As:
- Diani Reef Beach Hotel Ukunda
- Diani Reef Beach Resort And Spa
- Diani Reef Grand Ukunda


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Roundtable: African-Americans and Marriage
Topic: the status of marriage in the African-American community: Guests: Joy Jones, author of Between Black Women: Listening With the Third Ear; William July II, author of Understanding the Tin Man: Why So Many Men Avoid Intimacy; and clinical psychologist Jeffrey Gardere, author of Love Prescription: Healing our Hearts Through Love.
FARAI CHIDEYA host:
This is NEWS & NOTES. I'm Farai Chideya. Today, a special roundtable discussion on the state of black marriage in 2006.
But first, back to 1965. A report called Black Families in Crisis, written by future New York Senator Daniel Patrick Moynihan, sparked demonstrations around the country. The Moynihan Report, as it became known, concluded that, quote, "unstable black families threaten the fabric of black society." The report lamented the growth of black female-headed families, and increased rates of failed black marriages. At the time, many critics accuse Moynihan of blaming the victim.
More than four decades later, black marriage rates continue to decline, and nearly 70 percent of black children are born to single mothers or out of wedlock. Joining us to discuss this issue from our New York bureau, Jeffrey Gardere, a clinical psychologist and author of Love Prescription: Healing our Hearts through Love. From KPFT in Houston, Texas, William July II, author of several books, including Understanding the Tin Man: Why So Many Men Avoid Intimacy. And from our headquarters in Washington, D.C., Joy Jones, author of Between Black Women: Listening with the Third Ear. Joy wrote an essay in the Washington Post on March 26th titled Marriage is For White People.
Welcome everybody. And Joy, let's start with the story behind the title of your essay, Marriage is For White People. What happened?
Ms. JOY JONES (Author): Back in the '90s, I was leading a career exploration class for sixth grade students, and the students said we want to know how to become good fathers. The boys were especially interested in knowing what makes someone a good parent. And I was thrilled! I said, oh, we'll deviate from the curriculum. What I'll do is I'm going to bring in a panel of married couples so we can talk about marriage and raising families.
And they said, Miss Jones, you can nix the part about marriage. We're just interested in the part about being good dads, and that's when one student said, marriage is for white people.
CHIDEYA: Now, your essay suggests that what may have been considered a crisis during the era of the Moynihan Report is now kind of a norm in black families. Single, female-headed households predominate. What kind of hit you in your heart when you heard that kid say that?
Ms. JONES: Well, I was stunned that he had that particular viewpoint. And I want to say I did bring in that panel anyway--of married people--all of whom are still married, among those couples that I brought in for that discussion. I was encouraged that there was such an interest in wanting to know what are the parameters that define good fatherhood, because they were very seriously considering, what do I need to do to be there for my children in the event the I have them?
The girls were a little bit more traditional in their expectations in terms of falling in love and getting married, but it did concern me that none of the boys seemed to think marriage was such a great idea. Their reasoning was that marriage seemed to be so fraught with drama that most of the couples that they did know seemed to be arguing or divorcing, and it caused so much turmoil in the family that it seemed simpler, in their minds, not to even go through the charade and just focus on raising their children.
The ironic twist is, at that time, I was fully expecting to become married myself, and although that was ten years ago--ten plus years ago--I am a single woman, myself.
CHIDEYA: Jeff, let me turn to you. Do you buy into the thesis of the Moynihan Report that black families are crumbling because of the lack of marriage or the lack of stable marriage?
Dr. JEFFREY GARDERE (Clinical Psychologist, Author): I believe that we, more than many other groups, need the institution of marriage in order to hold our culture strong, in order to hold our people together, and we do ourselves a disservice when we believe that or buy into that marriage cannot help us as a people. I think it can do so many positive things for us, especially when we look at relationships between men and women setting examples as role models for us as to how we can love one another and raise families together.
CHIDEYA: William, Jeff mentions the different things marriage can do. One of them is actually increase your bottom line. Studies show that, not only do white families have a higher net worth than black families, but the lack of black marriage is actually eroding the kind of bottom line of the black family. How do you react to that, and then bringing in some of the issues of intimacy that you talk about in your book?
Dr. WILLIAM JULY II (Psychologist, Author): Let me just sort of reset some of this, because I think there's an important perspective that we need to bring in here. First of all, when I do interviews, I do as many interviews with Cosmopolitan as I do with Essence magazine, for example. Guess what? The issues that I am asked about are the same issues, because women have common concerns. Men have common concerns. And a lot of this that we're making a black issue is really a larger social issue, and my concern is, as a psychologist, I'm concerned about this idea of this over-pathologizing of African-American relationships.
So, to get to your actual question, that happens to be what I did my dissertation on was the whole idea of mate selection, how people select mates, why they select mates. And this whole idea about-basically, what we're getting into is this exchange theory orientation, where marriage becomes this quid pro quo thing. And that's good, but at a certain point, marriage has to be about a lot more than that. And you see these declining rates of marriage throughout society, not just in the African-American community. As Jeff alluded to, there are some particular issues and circumstances within the black community that might exacerbate these numbers, but this is not a black male pathology. This is an overall social issue we're looking at, and I think we do a great disservice to African-Americans if we tend to make things a black issue and pathologize ourselves.
CHIDEYA: William, let me follow-up about your exchange theory. I think that what you're talking about is basically women looking at men financially, men looking at women...
Dr. JULY II: And vice versa, yes.
CHIDEYA: ...on body size and all that stuff, so...
Dr. JULY II: Absolutely. That's exactly right.
CHIDEYA: So is that our problem? Or is that America's problem if it's not just a black problem?
Dr. JULY II: Yes, and I can't take credit for the theory. That's a widespread construct of the literature, but basically, and you hit exchange theory right on the head there, the idea is that that's been cross-culturally tested, and it's universal. And so, what I would like for every listener to walk away from this conversation with is that, yes, we have specific issues in black America that we need to address. You know, the numbers in this article are shocking, but at the same time, these issues are not just us. And so, we really can't solve this issue just in black America without solving it as an American issue overall.
CHIDEYA: Well, Joy, I just want to bring in another quote from someone else in the field--sociology. Ed Laumann, a University of Chicago sociologist, talked about how black men of all income levels are less likely than white men to be in a monogamous relationship. And he said, a black man with resources is in a seller's market. What would be the incentives to hold him down? Now, if you flip that, that leaves black woman like you and me in a buyer's--in market where we're seeking to buy, and there may not be enough supply. So what have you found? You're a single woman. You expected to married a long time ago. Are you disappointed that you don't have more options?
Ms. JONES: One of the twists in this whole thing--the situation is so nuanced that you can't just have a straightforward yes, no, black, white, kind of response. If you had asked me 10 years ago, are you going to get married? I would have said, yes. And if someone had suggested that I wouldn't get married, I would have said, oh, you're lying, and that I would be happy about it, I would be incredulous. But the truth is, I'm not married. I do not have children, and my life is pretty good, which is one of the twists. So yes, women are in a buyer's market, so to speak, but yes, we also have some viable and even wonderful options. Being single is not a curse, just like being married is not a magic charm.
CHIDEYA: Jeff, what about that? Have we reached a point where people are so frustrated by the failings of marriage, whether it's black folks or people in general, that people are looking for ways to be happy single, and that's one of the reasons why we see marriage rates declining?
Dr. GARDERE: Well, I think for too long, we have tried to push this myth that the only way to be happy is through marriage, and for those of us--I don't know about William, but I know for me certainly--for those of us who are married, that may not be particularly true. Marriage is one of the hardest things that you can ever do in life. If you are lucky enough or have, some would say, the misfortune of being in a marriage that is not working, then certainly we know that the grass is not greener on the other side. I think that each and every one of us has choices in life, and sometimes those choices are a little bit less for some. For Joy, she has found, if you will, joy in being single, and so it does not sound like the type of woman who's bitter about not marrying.
And I think we need to see more people out there like that, who perhaps would like to be married, but if it doesn't happen for them at that particular time in their lives, it doesn't mean that they're less than, and it doesn't mean that they can't go on and accomplish great things and be happy. And who's to say that someone like Joy wouldn't be married in the next couple of years to come? I mean, there's so many years for all of us down the road.
CHIDEYA: Well, Jeff, one of my friends got married for the first time in her 50's, so what you point out is absolutely true in life. There's not a single age at which people get married, but also, tell me a little bit about your book Love Prescription, because I think what you're talking about is really bringing men and women to a common table. Sometimes I wonder if we have a common assumption of what marriage is. Marriage can be financial, it can be emotional, sexual. It can be about filling expectations that your parents might have. How do you bring people to the table to have a common understanding of what they're getting into?
Dr. GARDERE: I think there's some very basic things that we need to look at with regard to marriage. Certainly, the first thing is, it must be about love. Marriages that, where people get together for convenience, or simply, and I think William alluded to this, simply just for the money doesn't really work. You have to be friends, you have to be in love, and you have to keep that going.
I think that each and every one of us as couples have to have a conversation as to what our marriages are about, and how they change in our lifetimes. How they change during the lifespan of that particular marriage, and how we need to adjust in order for each of us to still have some sort of happiness as we meld into, sometimes into one person, or one unit. That's a conversation that we don't have often enough and why I think we see a 50 percent divorce rate. Again, not just in African-American homes, but in homes throughout all of the communities. I think we want to make marriage work, but the reality is that quite often, it doesn't work. Fifty percent of the time, it doesn't work.
CHIDEYA: Go ahead, Joy.
Ms. JONES: Yeah, I would like to add to that. He talks about having a conversation. And one thing I think that conversation needs to include is not just talking about the things that both couples have as shared interests, but the things that are shared values. Among the couples that seem to be flourishing, that I have observed, they have shared values.
CHIDEYA: Well, Joy, I wanted to ask and William about your two books, because they seem kind of like bookends. William's book, Understanding the Tin Man is about men and intimacy. Your book, Between Black Women, obviously, from the title about women. Joy first. What do men need to know about how women view relationships?
Ms. JONES: Well, one thing that is that women have changed a lot. So, the woman you marry is probably going to be a little different than your mother or your grandmother. I think women today are looking for more partnership. They want more of a collaborative relationship, and not just an authoritative relationship.
CHIDEYA: And William, what do women need to know about men?
Dr. JULY II: I'm so glad you asked that question. We've got to stop over pathologizing black men. It does absolutely no good for a black woman, say for example, who's looking for a relationship with a black man, to have a preconceived notion that black men and black relationships are going to have this sick quality to them. We have to stop looking, you almost have a self-fulfilling prophecy when you go out into the romantic marketplace and you assume that you're going to have problems in a black relationship.
You have to look for a shared sense of values. That's what's going to make any relationship work. As Jeff said, we're hovering at around 50 percent for marriage failures, and that's because people don't marry--regardless of color--people don't marry for values. People marry for social exchange, and what you end up is when the BMW gets repossessed or when the job gets lost, then people go, oh my God, I don't even know you. I don't even like you now that I know you.
Dr. GARDERE: But William, wouldn't you say that people, for example, let's talk about women. Wouldn't you say that women of color, for example, and Joy, I guess you'd be the expert on this. I mean, wouldn't you say that it's a situation of where black women perhaps don't marry for different reasons than white women? White women perhaps make it more of a choice that they may not want to marry, because they want to pursue their professional agendas, where as I hear many black women don't marry because they haven't been able to find the right person, or the black men have not been available to them.
Ms. JONES: It's a multi-dimensional issue. Sometimes that might be the reason why a woman doesn't marry. Other times, she might look at some of the marriages around her and doesn't want that level of quality of marriage, and can't find a better match for herself.
I agree that we don't want to over pathologize things, but we also don't want to oversimplify things, either. There's more than one reason, and the reasons are often complex and interconnected. So you can't single out just one reason why a particular woman, white or black, doesn't marry. A lot of times, a marriage, particularly a good marriage, is a constellation of a lot of things lining up to make that magic moment happen.
CHIDEYA: In your article, Joy, you write, "I was stunned to learn that a black child was more likely to grow up living with both parents during slavery days than he or she is today, according to sociologist Andrew J. Cherlin."
I know that marriage doesn't not mean children, and children does not mean marriage, but in a world where those two concepts have been linked for millennia, is there an obligation, especially for people who want to have kids or who have kids, to try to figure this out and quickly? Joy, start with you.
Ms. JONES: Study after study shows that children do best in a husband and wife headed family. And I would want to encourage those people who are parents to, wherever possible, to try to work it out with their spouses, to afford our children the best situation possible.
CHIDEYA: Jeff?
Dr. GARDERE: I think it, at this point in our lives as people of color, and I agree with William, we don't want to over pathologize African-Americans, especially black males, but I think where we are in this world, where racism is still alive and well, that we need to work harder as African-Americans to have marriages, so that we can guide our children through this jungle that we call America, where they still are considered second and third class citizens.
CHIDEYA: William?
Dr. JULY II: I think the thing that's going to be the critical connection for us is having these sense of extended fatherhood that may not be within a family unit, because we are in a situation where we have so many single family households headed by a single mother households, but there are black men who could step up in roles as mentors in rites of passage programs, in social settings, teachers, role models in the community. These people can step up and show boys how to be men, and I think that's going to be one of the things that reconnects marriage in the black community, as boys learn to be men in the true sense of the word.
CHIDEYA: From Houston affiliate KPFT, we were hearing from William July II, the author of Understanding the Tin Man: Why So Many Men Avoid Intimacy. Also, at NPR New York, we spoke with clinical psychologist Jeffrey Gardere, author of Love Prescription: Healing Our Hearts Through Love. And finally, from our Washington, D.C. studios, Joy Jones, the author of Between Black Women: Listening With a Third Ear.
Thank you all for joining us for this thoughtful discussion.
Ms. JONES: Thank you.
Dr. GARDERE: Thank you.
Dr. JULY II: Thank you.
Copyright © 2006 NPR. All rights reserved. Visit our website terms of use and permissions pages at www.npr.org for further information.
NPR transcripts are created on a rush deadline by Verb8tm, Inc., an NPR contractor, and produced using a proprietary transcription process developed with NPR. This text may not be in its final form and may be updated or revised in the future. Accuracy and availability may vary. The authoritative record of NPR's programming is the audio record.


text:
Malignant lentigo
malignant lentigo n.
A precancerous brown or black lesion of the skin, often present in older persons, that appears on areas exposed to the sun, is irregular in shape, and is slow growing. Also called Hutchinson's freckle.
Tagged: m
Read Also:
- Malignantly
[muh-lig-nuh nt] /məˈlɪg nənt/ adjective 1. disposed to cause harm, suffering, or distress deliberately; feeling or showing ill will or hatred. 2. very dangerous or harmful in influence or effect. 3. Pathology. /məˈlɪɡnənt/ adjective 1. having or showing desire to harm others 2. tending to cause great harm; injurious 3. (pathol) (of a tumour) uncontrollable […]
- Malignant lymphoma
malignant lymphoma n. See lymphoma.
- Malignant melanoma
malignant melanoma n. See melanoma.
- Malignant melanoma in situ
malignant melanoma in situ malignant melanoma in si·tu (ĭn sī'tōō, sē'-) n. A melanoma limited to the epidermis and composed of atypical melanocytes that may be round with abundant cytoplasm.


text:
$9,790 CARFAX Value
No Accident or
Damage Reported
No accident or damage reported to CARFAX
CARFAX 1-Owner
Purchased on 01/06/15 and owned in AL until 09/26/17.
Personal Use
Driven an estimated 18,083 miles/year.
Service History
Last serviced at 46,094 miles in Montgomery, AL on 10/07/16 • Maintenance inspection completed • Transaxle replaced, Intercooler checked, Transmission checked


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Happy Monday!!!
I'm going to try and be better about my blogging this week... even if I don't have much to say.
Today is about photography. I'm trying to get pictures shot of my Christmas ornaments so that I can at least post what they looked like and maybe even sell one or two.
I'm going to be in the studio a bit tomorrow making tiny faces for the ring project. They're fun to make because they sort of take on personalities as the glass shifts and that's fun. They look different when they come out of the kiln too.. so it's sort of an adventure.
That's the plan for tomorrow... we'll see if it happens or not.
tiny blah blah blah for today...
I'm not so much into sharing what I'm having or not having at Starbucks because I feel like if I say I DIDN'T have Starbucks someone will worry about my finances and if I say I DID have Starbucks someone ELSE will pass judgment on how I chose to spend $4.50 of my money. See the predicament I'm in??? SO instead, you'll just have to wonder if I had coffee or not and if you're concerned about the fact that I might NOT have had coffee due to my pending unemployment, then please feel free to re-load my coffee card! :D
I didn't listen to music today, so I'm sort of boring in the tiny blah blah blah department. sorry.
Monday, December 14, 2009
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text:
Monday 23 September 1946
It was Monday, under the sign of Libra. The US president was Harry S. Truman (Democratic).
Famous people born on this day include Bernard Maris and Jim Mc.
Caesar and Cleopatra, directed by Gabriel Pascal, was one of the most viewed movies released in 1946
On TV people were watching Mixed Bill.
But much more happened that day: find out below..
You can also have a look at the whole 1946 or at September 23 across the years.
Old Newspapers
Have a look at the old newspapers from 23 September 1946 and get them!
TV Series
Which were the most popular TV series released in the last months ?
Which were the most popular movies released in the last months ?
Find out your future
Get a FREE Numerology report based on the digits of 23 September 1946!
Wish him/her..
Historical Events
Which were the important events of 23 September 1946 ?
- RC Saints - Feast day of Saint Adomnan of Iona, Saint Constantius, Saint Thecla.
- French Republican Calendar - Safran (Saffron) Day, second day in the Month of VendTmiaire
- Saudi Arabia - National Day (unification 1932)
- Japanese Autumnal equinox Day (????/Sh?bun no hi)
- Celebrate Bisexuality Day - September 23rd of every year is designated as Celebrate Bisexuality Day and celebrated by members of the bisexual community and their allies worldwide. Observed annually since 1999.
- Also see September 23 (Eastern Orthodox liturgics)
- In ancient Latvia, the second day of Mikeli
- Astrology: Usually the first day of sun sign Libra in the tropical zodiac.
- Traditional New Year's Day in Constantinople and Eastern Orthodox churches ? because of the birthday of August, not because of the equinox.
Famous Birthdays:
- Bernard Maris: French economist, writer and journalist who was also a shareholder in Charlie Hebdo magazine.
- Jim Mc: .
- Franz Fischler: Austrian politician.
- Genista McIntosh: Baroness McIntosh English politician.
- Davorin Popović: Bosnian singer-songwriter (Indexi).
- Anne Wheeler: Canadian director producer and screenwriter
Featured Contents
Would you like to write an original contribution on a topic related to this specific date and get featured on Takemeback.to ? Send us your proposal!
Music Charts
Which were the top hits in that special week of September 1946 ?
Top #2 songs in the USA
- Ole Buttermilk Sky - Kay Kyser & His Orchestra
- Rumors Are Flying - Frankie Carle & His Orchestra
Search For Your Ancestors
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...and if 23 September 1946 was your Birth Date then Join our Birthday Club!
Make this date unforgettable
Genealogy: find out your family heritage
Which were the most popular books released in the last weeks ?


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Few days ago we announced about the partnership between Squirro and itelligence AG. I was happy to have the opportunity to meet Dorian Selz, the founder of Squirro and Wolfgang Kroener, responsible for SAP Business ByDesign at itelligence AG, at the Cebit for a short interview. In this interview they explain how itelligence customers can benefit from the integration of Squirro, your personal digital research app, with SAP Business ByDesign.
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All right another week and another dose of the type, let's just skip the b.s. and get right into to it. Longtime Oakley team rider Travis Rice has just signed a multi-year contract with Quiksilver, and will be running the full kit—apparel and accessories. Another big change this time from down under—Aussi, Torah Bright has left Salomon snowboards to go head to toe with Roxy, and has reportedly been real stoked on the Magne-Traction boards. Canadian killer Dustin Craven has been officially added to the ThirtyTwo and etnies teams. Another note from ThirtyTwo; Stian Solberg has been added to their apparel line. Nate Bozung has a pro model on the way with Mathematics Snowboards. Grenade's four star general, Danny Kass is now seeing the world through Oakley goggles. Danbo also just swooped on a new dog, Big Vern. Chanelle Sladics is riding O-Matic boards.
Burton's recently teamed up with the Andy Warhol foundation offering up a line of snowboards, boots, bindings, men's and women's outerwear, thermals and a travel bags.
Team videos are the new black—Stepchild, Rome, CAPiTA, and DC all have projects in the works. We hear that things are on the upswing at Academy, and that Mike Casanova will be getting a pro-model soon. Colin Langlois just dropped in on a condo in Carbondale, Colorado. When we said Louie Vito was on Nike we didn't know they were making boots—they are.
In bummer news, a snowmobiler struck Doran Laybourne while snowboarding, resulting in a broken leg and cheekbone. DC rider, Norway's Torstein Horgmo just broke his back riding the European Open course after the comp' had been cancelled. Not to worry though, both dude's are making swift recoveries and are well on there way back. Till next week, everyone keep it safe, and keep it real.


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Spam messages are absolute productivity killers and outright annoying. They are unwanted, distracting and sometimes even malicious. In places like business organizations where email is the dominant means of communication, clogged up inboxes with thousands of unwanted mails is certainly bad. What's more worrisome is that spamming has existed ever since the inception of emails and unfortunately there is no stopping to it. Spammers get smarter and subtler every day to penetrate our inboxes in one way or the other.
Spam is so inevitably rampant that 60% of the emails circulated every day is basically spam. Though it is impossible to make emails 100% spam-free, it is possible to avoid spam entering your email system. Spam filtering is the most effective way to tackle spamming and in this article will give a brief introduction to spam filters, different types of spam filters and their need in today's world.
What is Spam Filtering?
Spam filtering is a process that involves screening of every incoming and outgoing message to find certain recurring patterns and filter out those messages that seem redundant, unwanted or malicious. Email servers of organizations will be equipped with Mail Exchange (MX) records that consist of many filters to identify spam. Thus, an incoming message has to pass through all of these filters before entering the email server and if it shows any signs of a spam message, these filters will identify the message and quarantine it in the mail exchange record. This ensures that all the spam messages are kept at bay and the email server process only mails that are wanted thus keeping the inboxes clean.
Different Types of Spam Filters
1. List Based Filters - These filters identify messages that are coming from blocked IP addresses and prevent them from entering the email server. The filters are an extensive database of all the blacklisted (blocked) and whitelisted (permitted) IP addresses that keeps updating every now and then.
2. Content Based Filters - Unlike list based filters, this type screens the messages based on the content present within the mail and the attachments they carry. Messages carrying keywords, phrases and attachments that resemble spam are identified and blocked from reaching the server.
3. Others - Though list based and content based filters are the most used ones, there are other spam filters like challenge/response systems and collaborative filters.
Importance of Spam Filtering
• If 60% of the inbox is filled with spam, a lot of your time is lost in reading these mails and deleting them from your inbox. This is a huge blow to your organization's productivity.
• Spam messages are sometimes intended to breach your network security and forcefully infiltrate your systems. Mails with viruses, malwares and Trojan horses are sent to your computer systems in the disguise of a spam mail.
• If 60% of the messages passing through the email server is spam, that is a huge waste of resource and time. It's like organizations incurring additional costs for processing mails that are not even wanted.
Securence is a leading provider of enterprise email filtering software that offers email protection and security services such as encrypted email, spam filtering, email archiving and continuity solutions to small and large businesses. To learn more about our email filtering solutions, visit Securence.com/solution.


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Content on this and the affiliated websites, unless noted, belongs to EESD. Material may not be copied or used without the express written permission of the District. Content on the EESD websites is for non-commercial, educational purposes; it is a communication tool to provide information to families in the District, for families considering our schools, for our staff and students, and for the community we serve. The District actively monitors the content on the District and school webpages, but we claim no responsibility for offsite content or linked websites. We make every effort to ensure that offsite content is appropriate and in good taste, and our employees are bound by Board Policies and Administrative Regulations which provide guidelines for the appropriate use of the Internet. We have no control over the ever-changing landscape of the Internet nor where outside websites might choose to link. We welcome your comments. Please contact the webmaster at 530-224-4100.
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Planejammer: The Seven Stars
Stray Manor
Deeded to Kaolin, Tavist, Ozzy, Drake, Dugan, and Etsuriko directly by Her Serenity for expelling Vecna from Sigil.
Permanent Guards and Wards (18th Caster Lvl) set on building
All portals and keys were mapped out by Fenelyn and Kaolin in a four day Portal Binge.
Drake's Campestri wander through Stray Manor (1-5 on a d20 when each floor, herds of 3-18 at a time)
"Astro" – a harriat, or Astral Forrager, this diminutive creature looks like a small brain with a pseudopod. It floats about slowly in the astral plane, feeding on stray thoughts. Found in Stray Manor the day after first testing the Elserryn Gate.
Main Floor
Squadron of trusted guards billeted in secret guards section
Olga of Ysgard in Seneschal's Quarters
6 Permanent Unseen Servants
6 Permanent Unseen Servants
Kaolin's Alchemical Setup installed in Main Lab (including brewing equipment) Key to Portal 1 hangin on wall next to Portal
Second Floor
Chapel rededicated to Celestian, Kaolin's tapestry of The Spelljammer is hung in here.
6 Permanent Unseen Servants
Third Floor
Arboretum -Plantlife of the Planes. One section is kept wet and marshy by daily create water spells, Drake's Campestri live here when they are not ranging through the building singing badly. A Giant Sundew lies in the midst of the plant growth, seemingly kept dormant by other exotics around it.
Doorway to Drake's office now sealed and smoothed over with stoneshape.
6 Permanent Unseen Servants plus three more that act exclusively as gardeners.
Fourth Floor
Circular access stoneshaped leading from the floor of Drake's quarters into his office.
6 Permanent Unseen Servants
Fifth Floor
6 Permanent Unseen Servants
|Portal Key
|1. Beastlands
|One Way
|Blue Feather from a Celestial Eagle
|2. Astral
|Two Way Erratic (1 on a 1d4)
|A Silver Ring set with Moonstone
|3. Astral, The Elserryn Cluster
|Two Way
|Whisper "Anall Nathraak" (needed from the
color pool side as well)
|4. Outlands
|Two Way
|Must spill blood and wipe on doorframe
|5. Bytopia, Layer of Dothion, near the Township of Yeoman
|Two Way
|Five fresh baked loaves of bread
|6. Beastlands
|One Way (person to Beastlands, all possessions to a
random Plane
|No key needed, constant effect
|7. Elysium
|Two Way
|Three Sprinkles of Holy Water
|8. Elysium
|One Way
|A Square Yard of Virgin Linen
|9. Mechanus
|Two Way
|Solve Equation (Int Check DC 20)
|10. Limbo
|Two Way
|Ball of Moist Clay
|11. Gehenna
|One Way
|Open Elemental Flame
|12. Gehenna, Layer of Mungoth in a cave.
|Two Way
|A Letter Intended For Smoeone Else
|13. Pandemonium
|Two Way
|Whistle Off Key
|14. Limbo
|One Way
|15. Elysium
|One Way
|Sincere Feeling of Remorse
Astral Forrager
Also called a harriat, this diminutive creature looks like a small brain with a pseudopod. It floats about slowly in the astral plane, feeding on stray thoughts. It is often kept as a pet by plane hopping wizards and psions.
In a game with both magic and psionics as well as some planar travel, astral forager may be taken as familiars. They grant a +2 circumstance bonus to saving throws against compulsions. Stats for a typical astral forager are:
Diminutive Aberration-HD ¼ d8 (1 hp); Initiative 4 size, +5 Dex); no attacks; SQ blindsight 30 ft.; Saves: Fort +0, Ref +5, Will +4; Abilities: Str 1, Dex 20, Con 10, Int 2, Wis 15, Cha 9; Skills: Hide +17, Listen +6; AL always neutral


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|A Lovely Couple
In 1994, during Bill Clinton's presidency, Gingrich spearheaded the Republican revolution that saw that party win the House for the first time in forty years. The victory also propelled him to the Speaker's chair. As a result, a frothing Liberal coalition was formed which immediately set about the task of the demonization of the "ultra-right-wing" Gingrich. And it was mostly made possible by Newt's bitter opposition to the Clintons' designs regarding health care.
Then, a mere eleven years later, Gingrich angered the base that once revered the historian and all-around bright guy, the guy they saw as the hero who had slain the Clinton health care dragon. In 2005, when Hillary was first dipping her toes in the presidential waters, Newt and Hillary were suddenly "an item", appearing together at news conferences and on talk shows, with Gingrich singing adoring praises for the first woman presidential wannabe.
|An Extremely Odd Couple
As it turns out, Mr. Gingrich and Mrs. Clinton have a lot more in common now that they have left behind the politics of the 1990's, when she was a symbol of the liberal excesses of the Clinton White House and he was a fiery spokesman for a resurgent conservative movement in Washington.I must confess, I am also guilty of forgetfulness in my zeal to see Newt run this time around. I also forgot about another stunning event a few years later, when Gingrich took to the couch with Nancy Pelosi who -- destined to be the speaker shortly thereafter -- actually makes Hillary look like a Rush Limbaugh dittohead.
In an advertisement to beseech our government to "do something" about Global Warming, Gingrich once again slept with the enemy by espousing a silly concept that he would later counter in a Congressional hearing. The video is here.
Two years later, Gingrich published A Contract with the Earth, which set off another kabuki dance in which Liberals praised him and Conservatives gasped. In 2008, just a year later, Gingrich published Drill Here, Drill Now, Pay Less. That tome had his newfound friends on the left questioning his commitment to the environment and the cause. Newt was fast becoming a human pendulum. In 2009, he pushed further to the right, testifying before a House Energy and Commerce Subcommittee hearing on "climate change" legislation in which he ripped Al Gore's ideas to shreds and challenged the former Vice President to engage in discussions on the matter.
Suddenly, Newt was ours again, but only for a while.
Just yesterday on the May 15th Sunday Meet the Press, Gingrich assaulted the Republican plan touted by Paul Ryan as "right wing social engineering", and endorsed a government mandate that citizens be required to purchase health insurance. As this country is slowly being dragged back to its senses by the Tea Party movement -- as evidenced by the mid term elections -- we're now not only fighting a formidable Progressive monolith...we're fighting the man who was once described by the New York Times as a "fiery spokesman for a resurgent conservative movement in Washington".
No thank you. I will not speak or write well of Newt Gingrich again until he is well past the age of a viable Presidential candidacy. He is a smart man and an excellent historical mind, but I do not want such a man anywhere near the Oval Office. Sphere: Related Content


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Warley Park Golf Club
Venue Rating
Rating 5.00 (2 Votes)
Service Rating 1 1 1 1 1 Rating 5.00 (2 Votes)
- Licensed for Civil Ceremonies
- All inclusive packages start from just £1, search 999 for 40 day and 70 evening guests
- Fabulously picturesque views from the wedding pier provide a stunning backdrop for your special photographs
- Personal wedding planner to help you create your dream wedding and ensure it all goes with only the one hitch on the day!
- Our private function room overlooks a row of 3 lakes and can cater for up to 140 for your wedding breakfast and up to 200 for your evening reception
- Visit our website to download our brochure and price list
Warley Park is situated in the picturesque village of Little Warley on the outskirts of Brentwood. It is ideally located just off of the A127 and M25 (J9) with a 300 space private car park and just a 5 minute taxi ride from Brentwood Railway Station. The club was purchased by the owners of the renowned Chelmsford wedding venue, Channels, in 2007 and since then the focus has been to replicate the outstanding quality of service and attention to detail which has been refined through the hosting of over 1000 weddings at Warley Park.
The Lakesview function room, which as its name suggests, offers a wonderful panoramic view of the course and its lakes plays host to over 100 functions each year ranging from full wedding celebrations through to High School prom nights and Christmas tribute nights. The maximum capacity is 140 seated dining guests or 200 evening / buffet guests.
Warley Park holds a licence for wedding ceremonies and civil partnerships and can advise you through every step of the process to arrange a non-religious ceremony. Additionally your personal wedding organiser will help you create the wedding day of your dreams for a price that is unrivalled in terms of value for money in the local area without you having to compromise on quality.
Every wedding is special to us and we have an excellent team of chefs and waiting staff who work closely with our wedding organiser to ensure that your day is not only perfect but runs seamlessly allowing the happy couple to relax and enjoy the proceedings.
In 2011 we constructed our wedding pier making use of a World War II floating bridge section which was actually dropped from a plane into our lake during the war after being forced to return home following a failed mission in Europe. Ever since its construction it has been the focal point of every wedding photographer we have played host to as the backdrop of lakes and weeping willow trees is truly unique in the area.
Our newly launched all inclusive packages have been tailored in such a way so as to provide excellent value for money whilst taking away some of the stresses of arranging your wedding.
For further information please visit our website and download the current brochure and price list from under our 'Functions' heading or contact Mandy Ray on 01277 224891 to arrange a tour.
|Warley Park Golf Club
Magpie Lane, Magpie Lane, Brentwood Essex, CM13 3DX
|01277 224891
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|Mrs Trihard and Toddler Trihard scour the undergrowth for treasure
"So what the flip has this geekorama pastime got to do with triathlon?" I hear you ask. Continuously running the same route can seriously damage your motivation to pull your trail shoes on. However Geocaching has helped me get to know a few different interesting routes, that I otherwise would not have known about, that I can easily introduce to my training. A lot of the time there will be a series of caches that someone has set up to introduce you to their favourite walk, typically along a loop. I have been blessed with a terrible sense of direction so being given the opportunity to properly scope out a running route first limits (although not completely eradicates) the possibility of me getting lost in the wilds of West Sussex and having to live as part of a pack of wolves for the next seven years.
Some of the routes I have discovered I can do directly from my house and others require a short car ride but I'm sure running a variety of routes will help stop me getting bored with my running routine for the coming months. And my first 10k is starting to sneak up, less than four weeks to go.


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Roeder standing by Emre
By Alex Livie
Last Updated: 01/01/70 1:00am
Glenn Roeder says Emre has been 'knocked sideways' by allegations of racism.
Newcastle boss Glenn Roeder has revealed that Emre has been 'knocked sideways' by allegations of racism.
The Turkish international has been charged by The Football Association with using racially-aggravated language during Newcastle's defeat at Everton on 30th December.
Emre is set to fight to clear his name and Roeder says the club will back the 26-year-old to the hilt.
"The allegations against Emre of racial abuse have knocked him sideways," said Roeder. "He is very upset about them and he is denying them all.
"The club is supporting him and standing by him. But this has nothing to do with his absence from the team at the moment.
"He has a calf strain and once that clears up, he will be available and up for selection."


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This article does not cite any sources. (December 2009) (Learn how and when to remove this template message)
Hydroida is an obsolete cnidarian order which united such animals as hydras, hydromedusae, and many marine attached hydroids. However, the group is paraphyletic and not composed from close relatives. But for the largest part, this group makes up what today is usually considered the subclass Leptolinae (or Hydroidolina) which also includes the colonial jellies of the Siphonophora which were not part of the Hydroida.
The "hydroid" cnidarians typically which grow up into large, elegantly branched forms. All the zooids of a colony are asexually produced from one parent zooid.
Examples of "hydroids" are:
- Craspedacusta sowerbyi, the freshwater "jellyfish"
- Hydra
- Air ferns, novelty "plants" and aquarium ornaments.
- Obelia
- Aequorea victoria of the suborder Leptomedusae, the crystal jelly- a bioluminescent jellyfish.


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Ian Andersen does a handstand on his bike that he is riding 20,000 miles.
John Leikness
Challengers Mike Sharp and Mark Flemmer handily defeated incumbents David Jopp and Donna Ouart in Tuesday's election.
A public input and informational forum was hosted Oct. 25 by Frazee Council candidates Mark Flemmer and Mike Sharp. The two candidates listened to and spoke to about 30 residents.
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I Wet the Bed On Pourpose
Personal Stories, Advice, and Support 104 People
Sometimes it is justso nice.
Stillwetshisbed 51-55, M 1 Response 4 Dec 20, 2015
I need to pee, so any masters (only guys)message me I haven't peed my bed in a while, and even though it's several months late, I need to christen my "new" bed the way I also christen new pants and underwear, peeing them.
pantswetter98 26-30, M 1 Response 2 Oct 17, 2015


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AstroTrac TW3100 Portable Pier Wedge
AstroTrac TW3100 Portable Pier Wedge
The AstroTrac Portable Pier Wedge adds rock solid perfomance! When you've got clear skies, perfect framing, and pin-sharp focus, the last thing you need is flexure spoiling your image. The unique patent pending design of the TW3100 wedge provides a rigid platform for your imaging equipment whilst retaining true portability.
The AstroTrac TT320X Portable Pier Wedge is quickly and easily mounted to the TW3100 with three 4 mm stainless steel mounting screws supplied with the wedge.
Tripod and Pier compatible, the TW3100 is perfectly matched to the AstroTrac Pier and can also be used with any photo tripod equipped with a standard 3/8" photo thread. Contact us to check compatibility with your equipment.
Do you need easy polar alignment? Specially made stainless steel adjustment and locking knobs with fine pitch aerospace threads give smooth and precise altitude and azimuth adjustment even under large load.
Compact and lightweight, the TW3100 can be easily carried in your airline luggage thanks to its compact size. Get your holiday or vacation off to a great start by avoiding costly excess baggage charges. Weighing just 2.2 lb (1 kg), you'll be pleasantly surprised by how little space and baggage allowance your TW3100 AstroTrac Portable Pier Wedge takes up.
The AstroTrac Portable Pier Wedge offers worldwide operation. With a latitude range of more than 90 degrees you can use the TW3100 from pole to equator. The easy-to-read latitude scale has 15 degree coarse increments and infinite fine adjustment via the conveniently located altitude adjustment knob at the rear.
The built in bubble level makes precise leveling easy, saving you time during polar alignment.
The AstroTrac Portable Pier Wedge is beautifully engineered, too.The silky smooth anodized aerospace alloy is perfectly complimented by the unique polished AstroTrac stainless steel knobs. The overall experience is as pleasing to the touch as it is to the eye, designed to give you many years of corrosion free reliability and handling pleasure.
The TW3100 is manufactured with loving care by highly skilled engineers at AstroTrac's factory in the UK using state-of-the-art CNC machinery.
AstroTrac Portable Pier Wedge Specifications
- Load capacity: 15 kg (33 lb)
- Weight: 1.0 kg (2.2 lb)
- Base diameter: 100 mm (4")
- Overall height: 125 mm (5")
- Latitude range: over 90 degrees
- Tripod mounting thread: standard photo 3/8" 16 tpi
- Pier mounting threads: 3 x metric 8 mm
- AstroTrac mounting plate: 3 x metric 4 mm
Additional Information
Questions & Answers
Have a Question?
Be the first to ask a question about this.


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- Please select a date to see the proper prices!
Description of the accommodation:
Rooms, services Just looking for accommodation in Italy? Take a look at the offer of La Dimora del Cardinale Maratea! The hotel is welcoming all guests in Maratea with 16 comfortable rooms to stay in. For meetings and nice evening chats the local café or the bar will provide an ideal location. If you wish to learn more about the exact scope of services provided by La Dimora del Cardinale Maratea (including any available for an extra fee), you will find them on the information sheet below.
Payment Advance bank card payment or credit card guarantee may be required for the reservation, depending on the chosen date, room and price.
Arrival, opening hours The earliest time to arrive is 11:00, the latest time to leave the rooms is 10:00. The personnel is at your service in Italian and English languages.
La Dimora del Cardinale Maratea rooms Rooms
- Please select a date to see the proper prices!
Accommodation services
Pet friendly, Bar, Cafe, Elevator, Roof garden


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Proflavine: A Feasibility Study for In Vivo Imaging of Oral Neoplasia
This study is currently recruiting participants.
Verified August 2017 by M.D. Anderson Cancer Center
M.D. Anderson Cancer Center
ClinicalTrials.gov Identifier:
First Posted: January 4, 2011
Last Update Posted: August 15, 2017
National Institutes of Health (NIH)
Information provided by (Responsible Party):
M.D. Anderson Cancer Center
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Show Detailed Description
The goal of this clinical research study is to learn if new imaging devices can help doctors decide if a lesion in the mouth is pre-cancerous or cancerous. The new imaging devices use different colors of light in mouth imaging.
|Head and Neck Cancer
|Drug: Proflavine Procedure: Imaging Device: Widefield Multispectral Imaging Devices Device: High-Resolution Microendoscope (HRME)
|Study Type:
|Study Design:
|Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
|Official Title:
|Wide-Field and High Resolution In Vivo Imaging of Oral Neoplasia Using Topical Fluorescent Dyes: A Feasibility Study
Resource links provided by NLM:
MedlinePlus related topics: Diagnostic Imaging
Drug Information available for: Proflavine hemisulfateU.S. FDA Resources
Further study details as provided by M.D. Anderson Cancer Center:
Primary Outcome Measures:
- Feasibility Assessing Oral Mucosa In Vivo with Wide-field and High resolution Images using New Optical and Topically Contrast Agent [ Time Frame: 3 years for patient enrollment; patient participation 10 - 15 minute imaging and tissue biopsy procedure prior to surgery for removal of lesion ]Assessments: 1) Standard white light headlamp where clinical impression classified into "normal", "abnormal low risk", "abnormal high risk", or "cancer"; 2) Widefield multispectral imaging digital images before topical fluorescent dyes, and 3) digital images by a widefield multispectral imaging device &/or high-resolution optical system after topical dyes where images reviewed by investigators blinded to clinical impression and histopathology diagnosis, classify lesions as "suspicious" or "not suspicious"; and, 4) Histopathology based on biopsy samples used as gold standard.
Secondary Outcome Measures:
- Number of subjects and lesions successfully imaged with wide-field and high-resolution optical microscopes after topical application of contrast dye [ Time Frame: 3 years for patient enrollment; patient participation 10 to 15 minute procedure including tissue biopsies done before surgery ]Several images of oral cavity mucosa taking approximately two minutes or less each, and removal for pathologic analysis of the measured sites
|Estimated Enrollment:
|Actual Study Start Date:
|December 2010
|Estimated Study Completion Date:
|December 2019
|Estimated Primary Completion Date:
|December 2019 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: Mouth Exam
Oral mucosa in vivo assessment with wide-field and high resolution images obtained using new optical imaging devices composed of cameras and microscopes, and with a topically administered contrast agent.
Drug: Proflavine
Swabbing of inside mouth with cotton-tip applicator soaked in 0.01% proflavine hemisulfate, a fluorescent dye which glows green in the dark, placed on proposed evaluation sites for up to 30 seconds.
Other Name: proflavine hemisulfateProcedure: Imaging
Imaging of inside mouth with multi-spectral digital microscope (MDM), the Identafi 3000, or portable screening system (PS2 or PS2.1) done first prior to swab with normal white light and second post swabbing of mouth with Proflavine at high magnification with High-Resolution Microendoscope (HRME).Device: Widefield Multispectral Imaging Devices
Widefield multispectral imaging device used for imaging inside mouth: the Multi-spectral digital microscope (MDM) and/or the Identafi 3000 handheld system, and/or portable screening system (PS2 or PS2.1) both before and after Proflavine swabbing.Device: High-Resolution Microendoscope (HRME)
High-resolution optical system used for imaging of inside mouth post proflavine application.
Show Detailed Description
Information from the National Library of Medicine
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Adult subjects with oral lesions undergoing surgical resection (i.e., only patients who are scheduled to undergo a surgery of the Head & Neck area to remove or biopsy oral lesions will be eligible to participate in the study). Patients with previous treatment are eligible.
- Ability to understand and the willingness to sign a written Informed Consent Document (ICD).
Exclusion Criteria:
- Known allergy to proflavine or acriflavine.
- Age less than 18 years.
- Pregnant or nursing females.
- The participant will be excluded from participation in another clinical research trial (i.e., a trial in which an agent is actively administered to the study subject), while being imaged (on active treatment) on this protocol.
Contacts and Locations
Information from the National Library of Medicine
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01269190
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01269190
|Contact: Ann M. Gillenwater, MD, BA
|United States, Texas
|University of Texas MD Anderson Cancer Center
|Houston, Texas, United States, 77030
Sponsors and Collaborators
M.D. Anderson Cancer Center
National Institutes of Health (NIH)
|Study Chair:
|Ann M. Gillenwater, MD, BA
|M.D. Anderson Cancer Center
More Information
Additional Information:
Keywords provided by M.D. Anderson Cancer Center:
Additional relevant MeSH terms:
Additional Information:
|Responsible Party:
|M.D. Anderson Cancer Center
|ClinicalTrials.gov Identifier:
|NCT01269190 History of Changes
|Other Study ID Numbers:
NCI-2015-01904 ( Registry Identifier: NCI CTRP )
|First Submitted:
|December 30, 2010
|First Posted:
|January 4, 2011
|Last Update Posted:
|August 15, 2017
|Last Verified:
|August 2017
Keywords provided by M.D. Anderson Cancer Center:
oral mucosa in vivo
Wide-Field In Vivo Imaging
High Resolution In Vivo Imaging
Oral Neoplasia
Topical Fluorescent Dyes
contrast dye
oral dysplasia
oral lesions
surgical resection
High Resolution Microendoscope
Identafi 3000
Multispectral Digital Microscope
Portable Screening System
Additional relevant MeSH terms:
Head and Neck Neoplasms
Neoplasms by Site
Anti-Infective Agents, Local
Anti-Infective Agents


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Welcome to Corporate Communications & Marketing
Bangor University's Corporate Communications and Marketing department is responsible for a wide range of marketing and communications activities.
Schools Liaison and Events
Our experienced and dedicated Schools Liaison and Events team are responsible for organising the University wide Open Days which receive throusands of visitors to the University campus. They arrange Schools Liaision and Widening Participation activities and represent the University at Higher Education fairs aimed at Undergraduates and Postgraduates throughout the UK and Europe.
Press and Social Media
Our Corporate Communications department includes the busy press office and Marketing Communications team, who are experts in social media and have driven the agenda in keeping Bangor at the forefront of developments in social media.
On-line Marketing and E-Communications
Our web & digital marketing team works closely with other web team members in IT services to ensure that the website is up to date and offers the latest information on our courses and research activities, as well as providing prospective students with valuable information about living and studying at Bangor University.
Our highly successful BangorTV website and Bangor University & Get Ready for University YouTube channels deliver video content which engages students from across the world.
The CRM team is an integrated team drawing together staff from within IT Services and Corporate Communications and Marketing.
This efficient and highly organised team is responsible for the University's Customer Relationship Management (CRM) system and works with staff from a range of departments to deliver engaging electronic communications messages to prospective students in the UK and internationally.
The publications team prepares and produces award winning publications. The publications produced are aimed at prospective students and applicants and include the undergraduate prospectus, the postgraduate brochure and various School specific leaflets and brochures. They also contribute towards other external publications and websites.


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Whether you're setting up for an outdoor summer soiree or just leisurely strolling around, maxi dresses can be your go to outfit. Not only is it easy to throw on a dress, you make a total chic statement in the process. One of my favorite places to score super cute and affordable maxis is Windsor.
So now you're thinking, "I love the maxi dresses but I'm not sure how to wear them." There are so many different ways to rock a maxi, girls! As always, it's so important to put emphasis on your smallest part (your waist). If the dress doesn't already gather at the waist, belt it!
Accessories are always a must. And hats aren't just for winter, ladies! Throw on a huge floppy hat like mine from Windsor and give us glam realness at all times. These dresses give you comfy glam, perfect for those hot summer days. Cheers!


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Results 1 to 7 of 7
Thread: DB Question
10-09-10, 05:14 #1Registered User
- Join Date
- Oct 2010
- Posts
- 1
DB Question
According to Codd's Tweleve rules which are considered as a basics of the relational database system, which one of the following three systems: Oracle, DB2 and SQL server is most applied and relational than the others?
Please give me your opinion and why.
10-09-10, 05:32 #2Jaded Developer
- Join Date
- Nov 2004
- Location
- out on a limb
- Posts
- 13,692
don't care
as long as the software is SQL compliant
as long as the client/customer is good for the cash
..thats fine by me.I'd rather be riding on the Tiger 800 or the Norton
10-09-10, 08:49 #3SQL Consultant
- Join Date
- Apr 2002
- Location
- Toronto, Canada
- Posts
- 20,002
why does it matter?
if you work for an organization that has only one of those three databases, then that's the one you'll be using
if you work for an organization that has more than one of those three databases, choose whichever one you like
the only people who ask questions like "which database satisfies more of codd's 12 rules" are teachers, giving homework assignments
rudy.ca | @rudydotca
Buy my SitePoint book: Simply SQL
10-09-10, 10:48 #4Resident Curmudgeon
- Join Date
- Feb 2004
- Location
- In front of the computer
- Posts
- 15,579
According to Gartner, Oracle serves the most users worldwide, followed by DB2, followed by Microsoft. So I guess that means that Oracle is applied more often than DB2, which is applied more often than Microsoft.
TCP numbers vary wildly, depending on configuration. Overall Microsoft tends to be the least expensive, followed by IBM, then by Oracle. There are multiple sources for TCP information, and since no two configurations produce exactly the same TCP costs it is very hard to produce comparable numbers.
Based on personal observation of developers and Database Administrators, I think that those numbers are roughly reversed. More developers seem to use Microsoft, followed by DB2, followed by Oracle.
Some of the difference can be attributed to "stale numbers" where systems that were created on a given platform years or decades ago may continue on that platform even when no new development has been done for a long time.
The short answer is that you can pick the order that suits you, then find statistics to back up your opinion!
-PatPIn theory, theory and practice are identical. In practice, theory and practice are unrelated.
10-11-10, 09:15 #5Registered User
- Join Date
- Apr 2008
- Location
- Along the shores of Lake Michigan
- Posts
- 242
As legacy systems are still in use, I think that tends to over-inflate the Oracle numbers. My last job, we had a legacy system on Sybase. Our CIO wanted them to migrate us to MS SQL. The third-party vendor said they would if we paid for the development of their migration tool ($50k +). Our CIO said, F*** off, we'll be your last supported Sybase customer, and based on contracts, we could've been. They developed the tool, we were their first migration to MS SQL and were their reference for other clients looking to do the same. Worked out well for us. While numbers can mean a lot, they alone are not a true indication as to the direction of application development. As Pat alluded to, find what works for you and your environment. Hell, it could be MySQL or even, **shudder**, Access.-- You can't be late until you show up.
10-25-10, 07:20 #6Registered User
- Join Date
- Aug 2010
- Location
- Singapore
- Posts
- 197
i hope it is oracle which satisfies the 11 1/2 rules
10-25-10, 11:48 #7World Class Flame Warrior
- Join Date
- Jun 2003
- Location
- Ohio
- Posts
- 12,595
Oracle 11.5 satisfies 11 1/2 rules, but we are looking forward to Oracle 11.6.9 which will satisfy nearly 11 7/10 rules. Woot!If it's not practically useful, then it's practically useless.
www.chess.com: "sqlblindman"


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If a price was so attractive that you forgot to read the buyers feedback for a shop and you end up receiving a 32GB-Class10 card that turns out to be a hacked 2GB-Class2, your first action as a buyer should be:
- leave a feedback to warn the others, or if you left a positive feedback too quickly, find the link "Follow up on Feedback Left" on the bottom of the eBay page to review it.
Proceeding this way, you will minimize the damage to only a waste of time in the end.
Now you may be tempted to see if you can use the fake memory card for its actual capacity (likely 2GB at best).
Putting in the balance how valuable is your time compared to the real value of your now-free eBay item will probably convince you not to waste more than 30 minutes trying to make this card usable (not for taking photos or keeping backup of course, but might still be good enough for mp3 players).
So, rather than spending hours reading forum and specialized web sites, here's just a quick'n dirty procedure that you could try first:
Get the following 2 small freeware tools:
The popular tester H2testw
A simple paritionner that can be used on SD cards: MiniTool Partition Wizard Home Edition
1. Finding out how much capacity is actually usable with h2testw
- Start h2testw.exe, click Select Target and select your SDCard
In Data Volume, specify a reasonable limit to test: your card's real capacity is likely to be the lowest possible so try around 2300 MByte. This phase will take about 20 minutes.
- Click "Write + Verify" and let the test run. Looking at the Writing, you will already give you an idea of the real speed index (2MBytes/s=Class 2, ...)
- When the "Verifying" phase starts, expect to see errors in red as soon as the real capacity is exceeded.
2. Setting the card to its real capacity
- With Partition Wizard Home Edition, select -carefully!- the drive corresponding to your SDcard
- Delete the whole partition
- Create a new one of 2000MB (1.9 GByte)
- Format to your desired standard
- After checking once more that you didn't wipe your main Hard Disk, click on the "Apply" button to make the change effective.
3. checking the fixed card
- Run either a Surface test from Partition Wizard or use H2testw again to ensure that everything now works as it should.


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Powerful coaching tips: how many eyes are shining around you?by Stacie ~ October 5th, 2015. Filed under: Coach Softball.
Share this article: CLICK HERE to Tweet
I heard these and I furiously wrote them down because they really hit home!
I was at an essential oils leadership training event when I heard these powerful coaching tips …
- Be aware of your words and make sure they pull your team together not tear them apart.
- Your team owes you nothing, you owe them everything.
- Awaken possibility in others (you know you're succeeding when their eyes are shining).
If their eyes aren't shining, ask yourself…
- Who am I being that my players' eyes are not shining?
(If you're a parent … Who am I being that my children's eyes are not shining?)
Coaching is not about wins or power but about how many eyes are shining around you.
Stacie Mahoe shares lessons learned from decades around the diamond. Enjoy her unique insights on softball and life from years as a player, coach, parent, and fan of the game.


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Every few months, we like to take a couple weeks to play some interactive games. This time around, JP (Japesland), Kaze, Jack (R86), and Casey (CutsceneAddict) play a game of JP's own creation called "Kantoku-san." What if you were the kantoku of all anime studios in Japan? Listen in and post your own opinions in the comments below!
As always, every episode of The TangleCast will be covering a different topic, from anime reviews, to discussions on spirituality, to listener mail, and everything in between. Please join the conversation by commenting below or submitting a question at our contact page!
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Leave a Reply
My answer to #1: Hatoful Boyfriend. It could make for a fun series of shorts.
(also, I don't know very many VNs and manga, so the pool from which I can pick is limited)
…wow. JP and Kaze have really long arms.


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Nothing is more iconic in Rochester than Genesee Beer. The brewery has begun to roll out a series of pilot batches of new beer. This recipe combines their premier IPA with another local classic: Buffalo Chicken Dip. The flavors of the this pilot batch comes out when combine with blue cheese and hot sauce. This new twist on a classic recipe is a great appetizer for any gathering.
The Marinade
2 Cups Genesee IPA
2 Cups Ginger Ale
The Dip
2-3 Large Chicken Breasts
1 Cup Blue Cheese
32 OZ Cream Cheese
1 Cup Mozzarella
1 Cup Cheddar Cheese
1 Cup Parmesan
1 1/2 Cup Red Hot
Pinch Garlic Powder
Pinch Black Pepper
2 Bottles Genesee Brewery IPA
1. Marinade the chicken overnight in the IPA/ginger ale mixture.
2. Pour two bottles of IPA into a pot and reduce for 30 minutes or until the beer reduces by half.
3. While the beer reduces grill the chicken. Pour the left over marinade over the chicken while grilling it. This creates a good char over the breasts.
4. When the beer finishes reducing add the cheese and the red hot. Lower the heat and let simmer until everything melts.
5. Dice the chicken and add it to the cheese, leaving a handful aside for garnish.
6. Pour the mixture into a serving dish. Top with more cheddar, mozzarella, and grilled chicken. To be fancy crisscross red hot across the dip before serving.
This recipe is based on a dish served at Lovin Cup's Hometown Throw down by Marshall St Bar and Grill. If you would like Marshall St. to cater your next event contact Kelly at 585-325-2191.


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Winterbliss by GlacialNecrothynWatch
©2012-2017 GlacialNecrothyn
Though this image is old as you say in your description. I like it a lot and can see why so many others have been interested in it as well (according to your views). The snow has a soft feel, the trees void of leaves and life, and the mountains portraying an aura of isolation. I like the dusty hue of the sky and the way the snowfall is blurred against the camera's view. It gives a more natural flow to it rather than depicting it as still. The poses you chose here are good as well. Both declare that you're ready to fight and do what you need to against the foe off screen. The expressions also display this perfectly. The effects are very nice too and I particularly like the one in Avanne's hand. It has a very lovely fireball look and defined magical ripples.
So, even if this is older, this piece is still beautiful for the time it was crafted.
So, even if this is older, this piece is still beautiful for the time it was crafted.
Even though your remake of this picture kicks this one's ass, I still love this one. Then again I love snowy pictures.
Very nice effects here, and the trees are awesome
"I remember watching you draw quite a bit of this. I still like how personal it is, as well as how it shows off the ferocity you've always carried with you. Rock on, brotha."
Thanks man, glad you still like it as much to this day as you did then. Perhaps sometime when I stream the reboot version of it you can watch me draw that one too!
I like how this looks even if it is an oldie. I consider it one of your "classic" works It's very nice
Posing is good and expressions are good and I like the trees in the background!
Posing is good and expressions are good and I like the trees in the background!
Even if it is 'out of date', this is still in your 'best art ever' list. x3


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Hi, I would like to know if somebody can help me to clear a couple questions related with the Thello train EN 220. Today, I bought an train ticket from Milano Centrale to Paris Gare du Lyon . However, I dont have any international train experience, so I just wondering if somebody could recomend me a online source information where I can know all the required information to board and use my ticket. Here there are some of the questions I am confused :
1. I bought a cabine 2 Lit ticket, may I use it with my wife? I heard that Thello only allow persons of the same sex on their cabine or couchettes?
2. What is the boarding process for an internacional train on the Milano station(Milano centrale)? Do I have to validate my ticket? If so where? Are the international trains published on the station board?
Thank you very much in advance for any information you can provide me.
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Thello EN220: Milano to Paris question
Hi, I would like to know if somebody can help me to clear a couple questions related with the Thello train EN 220. Today, I bought an train ticket from Milano Centrale to Paris Gare du Lyon . However, I dont have any international train experience, so I just wondering if somebody could recomend me a online source information where I can know all the required information to board and use my ticket. Here there are some of the questions I am confused :
Report Abuse
1. Never heard that.
2. No need to validate since your ticket is for s specific time, train, and seat. The international trains are just like any other train - nothing different. It is list on the boards with the other trains, Just find it and get on. The days of having your passport checked at the border is over.
Report Abuse
Thanks for you early reply. Do you know where I found information about the boarding process at the Milano centrale?
Report Abuse
1. Did you book on Trenitalia? Did you enter 2 people and select the 2 person cabin and select complete cabin?
2. Find your train and get on. All trains are listed on the overhead electronic boards with which track # (binario). Whenever you have assigned seating (in this case assigned cabin) on a train in Italy, you don't have to validate your ticket. The personnel on board will check your ticket.
Here's some video from the train.
Here's some more info.
Use only bottled water on board as the water in the sinks is not potable.
Report Abuse
I still don't understand your question about boarding process. Boarding process at Milano is no different than any other train station in Italy or Europe for that matter. You find the track/platform number (posted about 30 mins prior to train arrival, walk down the platform till you find a car number that matches the car number on your ticket. Find the stairs at either end of the car, climb the stairs, store big pieces of luggage in the bins, stumble down the aisle till you find your seat number. Store carryon luggage in the overhead rack and sit down. Were you expecting something different. Like, "Papers, please !"
Report Abuse
fmpden, At not time, I said papers , However please take in consideration that I have never taken a train in Europe before. thanks for the info anyways.
1. I did not use TrenItalia website. Instead of TrenItalia I bought the tickets directly at Thello website. The ticket is a Cabine 2 lit.
Thanks both for the explanation about the boarding process.It is exactly what I was looking for.
Report Abuse
>>>store big pieces of luggage in the bins, stumble down the aisle till you find your seat number<<<
On overnight trains, keep your luggage with you in your cabin and always lock your cabin. There will be a dining/snack car, but you can take some snacks/drinks/wine on board if you want.
Longer distance trains are usually in the station longer than local trains so you have a bit more time to board. It may be in the station for boarding no more than 15 minutes, but possibly a bit longer.
If you will be using other trains in Italy, only the slow R trains (no reserved seating) require validating of tickets before boarding (yellow machine track side). All other Trenitalia trains are reserved seats so you don't need to validate. Some trains passing through smaller towns stop for as little as 1 minute so you need to be ready with your belongings at the door to get off or on. Stations that are not pull through have a bit longer stops as the trains have to pull in and then back out.
This link is about Rome, but it shows you how to check the station boards, find your track/car, etc. Scroll down to the pictures
Report Abuse
kybourbon, Thank you very much for your reply.
Dont you know if there is a website with a map and information about the milano centrale station. I mean diferent of the trenitalia website. I just want to know all i can about it.
Thank you
Report Abuse
If you are going to use this train from Italy to France BEWARE it often runs very late!
When I used it it was five minutes late into Milano Centrale (not a problem - it was due a long stop) and it was over an hour late in Dijon so I missed my connecting TGV to Lille. The train crew let me stay on to Paris and Eurostar in Paris changed my Lille London ticket to Paris London free of charge - WELL DONE EUROSTAR!. However, my prebooked/prepaid ticket onwards from London was no longer valid so I had to pay GBP 40 for a new ticket. Thiello have refused to contribute to this.
Thiello is part of Transdev-Veolia. In France Veolia provide infrastructure services such as water and sewage . .. .
Report Abuse
I know Pee.D that you just joined and are eager to contribution, but a good habit to develop is checking the dates of the postings that you are respond to or digging up. The OP was inquiring about a train in 2012. I am sure he has been to Italy and home.
Sign in to comment.


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|A new study tracked a pronounced decline in the
use of donor hearts overall in the United States.
dailyRx News
As the waiting list for heart transplants has grown longer, fewer hearts have become available for transplantation in the US in recent years.
A new study tracked a pronounced decline in the use of donor hearts overall in the US.
The authors of this study noted that some US regions used more donor hearts than others. As a result, they suggested the need for updated and standardized guidelines on donor heart use and acceptance.
Kiran K. Khush, MD, of the Stanford University School of Medicine in Palo Alto, CA, led this study.
"We, as a heart transplant community, are using a small fraction of available donor hearts for transplantation, and we have become more conservative over the past 15 to 20 years in terms of donor heart acceptance," Dr. Khush said in a press release.
Dr. Khush continued, "This finding is troubling in the setting of a national donor heart shortage and an ever-growing number of critically ill patients awaiting heart transplantation."
These researchers studied national trends in donor heart use for transplantations by looking at data from the Organ Procurement and Transplantation Network. All potential adult heart donors were included in this study, from 1995 to 2010.
There was a huge drop in donor heart acceptance, from 44 percent in 1995 to 29 percent in 2006, Dr. Khush and team found. In 2010, donor heart acceptance went back up to 32 percent, however.
This article is related to the Whitepaper: Software Automation in the Blood and Biologics Industry. To get the full details, please download your free copy.
This article is related to the Whitepaper: Software Automation in the Blood and Biologics Industry. To get the full details, please download your free copy.
Each person wanting to donate must first enroll in his or her respective state's organ donor registry. The person's medical condition at the time of death shows which organs can be donated.
But not all organs (in this case, hearts) are accepted, Dr. Khush and team pointed out. Some reasons why donor hearts were not accepted included factors like the donor's age, gender and medical conditions. The authors found that more potential donor hearts were from donors who were older or had health issues, which most US regions considered unwanted characteristics. The issue of donor hearts having these unwanted traits was linked to a clear decrease in donor heart acceptance.
Dr. Khush and team also found that some regions used more donor hearts than others. This highlighted the fact that donor heart acceptance practices haven't been standardized. The authors suggested a need for standard clinical guidelines and more intense efforts to make areas with low donor heart use increase their acceptance and use rates.
This study was published Feb. 10 in the American Journal of Transplantation.
The National Heart, Lung, and Blood Institute and the National Institute of Diabetes and Digestive and Kidney Diseases funded this research. Dr. Khush and team disclosed no funding sources or conflicts of interest.
Reprinted with permission. Originally published at www.dailyRx.com.
More from dailyRx.com:
The Gift of Life: Transplants Save Many, More Still Needed: http://www.dailyrx.com/organ-transplants-saved-millions-years-life-last-25-years
Going Under? Talk About Your Worries: http://www.dailyrx.com/anesthesia-may-be-safe-patients-are-advised-discuss-concerns-anesthesiologist
A Drink a Day May Not Be Good for Everyone: http://www.dailyrx.com/alcohol-moderation-may-only-protect-health-certain-age-groups
Three ways to use this information now:
1. Share this post on LinkedIn or Facebook
2. Leave a comment in the box below
3. Visit http://www.organdonor.gov to learn how to save a life by becoming an organ donor.
Three ways to use this information now:
1. Share this post on LinkedIn or Facebook
2. Leave a comment in the box below
3. Visit http://www.organdonor.gov to learn how to save a life by becoming an organ donor.
Sheila Yu is a health news reporter for the dailyRx News Network, focusing on health promotion and outcomes. She graduated from the University of Texas Health Science Center at Houston with a Master of Public Health.
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A Randomised, Open-labeled, Multi-center Study to Investigate the Safety and Efficacy of OROS Hydromorphone HCL Comparing With Morphine SR in Cancer Pain Patients
This is a phase III, randomized, open-labeled, active-controlled, multi-center study in 110
adult patients with cancer pain, requiring strong oral opioid analgesics. This study period
is divided into 3 phases: screening period (14 days prior to randomization/dosing), dose
titration phase (3 to 14 days), and dose maintenance phase (14 days). Patients will be
evaluated at 4 scheduled clinic visits and contacted by telephone daily between visit. The
screening will last up to two weeks. Patients with cancer pain who meet entrance criteria
for the study will be identified. The study will be explained and informed consent will be
obtained. Patients who have met the criteria at screening will start approximately 17-28
days treatment of either OROS hydromorphone or Morphine SR (sustain release). During the
treatment, dose adjustments are permitted in steps at titration. Dose level may be titrated
upwards or downwards every 48 hours in the titration phase. The dose should be titrated by
the Investigator according to the patient's analgesic requirement. A patient is considered
stabilized when, for a minimum of 2 consecutive days, the requirements of rescue medication
are maintained at 3 doses per day or less. If necessary, dose titration is also permitted
during maintenance phase using the same criteria used in the titration phase. Patients
should be titrated to adequate effect no more frequently than every 2 days in maintenance
phase. Morphine hydrochloride will be used as rescue medication for breakthrough pain. No
other opioid is permitted during treatment period. Adjuvant medications such as paracetamol,
non-steroidal anti-inflammatory drugs, anxiolytics, antidepressants, antiarrhythmic drugs,
hormone therapy, corticosteroids, anticonvulsants, and neuroleptics are allowed but must be
maintained at stable doses for the duration of the trial. Analgesic efficacy is assessed
using the short form of the Brief Pain Inventory (BPI). Equivalence of efficacy will be
assessed using the "worst pain" item of the BPI (BPI Question 3) as the primary efficacy
assessment. BPI Q3 & Q6 (Question 3 & 6), study medication usage, and requirements of rescue
medication will be recorded daily by patients for both treatment groups. Other pain
assessments in the BPI will be performed by patients and the Investigator at 4 visits
(baseline/randomization, Visit 3 and 5, and FINAL visit). And Global assessments will be
performed by patients and the Investigator at 3 visits (Visit 3 and 5, and FINAL visit).
Safety will also be assessed through physical examinations and vital signs, clinical
laboratory evaluation, and monitoring for adverse events. Patients who have met the
criteria at screening will start approximately 17-28 days treatment of either OROS
hydromorphone or oral Morphine SR. During the treatment, dose adjustments are permitted in
steps at titration. The dose should be titrated by the Investigator according to the
patient's analgesic requirement. For patients not routinely receiving opioids, the initial
dose should not exceed 8 mg OROS hydromorphone every 24 hours (in the morning) or 30 mg
Morphine SR twice daily.
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
To demonstrate the clinical equivalence of efficacy between OROS hydromorphone HCI and Morphine SR in patients with cancer pain at baseline, visit 3, 5 and final visit.
Johnson & Johnson Taiwan, Ltd. Clinical Trial
Study Director
Johnson & Johnson Taiwan Ltd
Taiwan: Food & Drug Administration
August 2008
December 2008


text:
Dogtanian Special Trailer (1981)
01 January 1981 Adventure, Animated, Family
In the France of Louis XIII, the brave Muskehounds risk their lives for their king and their country fighting the ambitious Cardinal Richelieu who threatens the throne of France. Based on the famous novel by Alexandre Dumas' The Three Musketeers ". It is the story of Dogtanian, a young swordsman who achieves his dream of joining the royal guard by virtue of his courage, valor and cunning with the sword. A story based on true friendship and a motto worth fighting for: "One for All and All for
Watch the official Dogtanian Special 1981 trailer in HD below or find more Dogtanian Special videos on Vidimovie.


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The upstanding but wayward folk of BareBones are collating another selection of high grade stuff to cram into the second issue of their tasteful organ.
Any suggestions or submissions should be sent to here;
2012 is the year for olympic nitwittery, 2010 is the year of the BAREBONES. Get in and get some before they're all living on yachts in the Med, drinking margaritas shooting automatic weapons at shoals of passing tuna.
How unPC and highly uncontactable.


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Suffer from thinning or thin-looking hair? Then Alterna Caviar densifying Foam may be the solution. This lightweight styling foam let her look visibly fuller and thicker. The hair gets more body directly. This foam of the Alterna Caviar Clinical Daily densifying line also strengthens the hair as hair breakage to do some more porous to avoid her.
Alterna Guinea Clinical Daily densifying Foam is suitable for both men and women who suffer from thin or thinning hair. The hair is visibly thickened and will also feel fuller. The special composition of the foam densifying provide the perfect care, styling and look. Including the Red Clover Complex is strengthening from within the Color Hold causes the vibrancy of hair color is trapped and retained, and the Control Complex contributes to the aging of the hair is prevented.
Alterna also includes Guinea Clinical Daily Foam densifying extracts of caviar and vitamin C to soften the hair and to give unprecedented shine. In addition, an exclusive mix of enzymes and minerals ensures that the absorption of essential nutrients is facilitated.
Alterna Caviar Clinical Daily densifying Foam is available in a 150ml container.