text:
- Please select a date to see the proper prices!
- Meal can be requested on the spot
Best offer
103 € / person / night, no meal
Description of the accommodation:
Rooms, services Residence Ca' Beregana Vicenza is offering nine tasfefully furnished, nice rooms for those looking for a place to stay at in Vicenza. Car parking possibility is available nearby. Refreshing wellness services will be available on the spot, you may also use <a/an> steam room. Nearby bike rental opportunities may provide an excellent option for those who love to spend their leisure time actively. Upon preliminary notice airport transfer is provided. You may secure your valuables in the safe. If you have a suitable portable device, you can connect to the Internet via a wireless network (WiFi) available at the hotel. If you wish to learn more about the exact scope of services provided by Residence Ca' Beregana Vicenza (including any available for an extra fee), you will find them on the information sheet below.
Payment In order to finalize the reservation you may be required to provide credit card guarantee or advance payment by credit card, depending on the chosen room, date and price.
Arrival, opening hours The earliest time of check-in is 14:00, the latest time of check-out is 10:00. The personnel of the hotel can speak with you in Italian and English languages.
Residence Ca' Beregana Vicenza rooms Rooms
- Please select a date to see the proper prices!
Accommodation services
Free WiFi in shared places
Bike rental at the accommodation
- Wellness section, relaxation
- Steam room
- Pool (Outdoor - seasonally open)
- Finnish sauna
Default services: Garden, Safe deposit box
Airport transfer
Hairdryer, Washing machine


text: I got an iPhone 3G last year and it was pretty cool, but recently I was having to charge it at least twice per day. I got a replacement battery and watched a YouTube video four times showing how to do the replacement. I started the surgery and thirty minutes later the phone was destroyed. I thought about getting the iPhone 4. But even had it been available I had decided against it. I don't want another device that requires surgery in order to change the battery. Plus the storage isn't expandable. So far I like the Aria. It's definitely faster than my old iPhone. I love the fact that I just throw my music & videos into folders on the memory card and there they are in the phone. On the iPhone I'd have to boot into Windoze (I'm a Linux guy) then run iTunes, then do a sync that typically took more than an hour. Go Android!

subset: commoncrawl


text:
VERY FINE ANTIQUE/VINTAGE LACE TRIM/EDGING (Lace A)
Sold for:
Start Free Trial
or Sign In to see what it's worth.
- Sold Date:
- Source: eBay UK
* * * * *
A lovely piece of extremely fine antique lace edging approx 1.5" wide x 37.5" long
One end is hemmed and the other is raw
It is off-white and is in excellent condition with no damage that I can see
As it is so fine, I have temporarily tacked it to a piece of tissue paper
I know nothing about lace - except that I can appreciate the huge amount of
painstaking work that it involves - and cannot therefore date or attribute this piece
I am sure you will know what you are looking at and hope you bid appropriately!
I shall be listing several other pieces in due course so please look
Payment please within 3 days of purchase only via PayPal
P&P shown is for within the UK
Please contact me for overseas costs or with any questions
Thank you for looking!


text:
Praeses is seeking qualified candidates for the National Account Manager position within the Correctional Services Division.
Our Ideal Candidate:
Possesses excellent interpersonal skills with the ability to build long-term, successful relationships with new and existing customers.
Possesses strong oral and written skills to facilitate communication between various levels of customer and vendor hierarchies.
Has solid negotiation skills that can be applied to contract terms and requirements.Is very detail oriented with strong organizational and time management skills conducive to a high multi-tasking environment.
Maintains a level of analytical awareness to identify trends in customer specific services.
Has knowledge of and/or experience in creating requests for proposal and reviewing and/or evaluating submitted proposals.
Manage vendor contracts to ensure all financial, technological, quality and service requirements are met.
Effectively communicate the needs of the customer and represent the interests of customer to vendors.
Act as single point of contact for all service and contractual issues and subject matter expert for industry trends.
Manage daily operations issues to relieve customers of administrative burdens and to ensure adequate and timely response from vendors if necessary.
Obtain requirements and prepare requests for proposal for service and negotiate resulting contracts.
Reconcile monthly commission monies for the customer and report any potential abnormal trends.
Coordinate implementations of new and existing services and transitions of new and existing services.
Maintain industry knowledge to keep customers abreast of new trends and technologies.
Little or no travel required.


text:
To be or not to be...
Why Do I Need This Smart Heating Boiler?
If you are using so-called centralized system of heating, you possibly sometimes think of passing to the independent system. We bring you not only the independent, but also a very profitable solution. You will be able to receive payments for the calculations which are made by a boilers heating element (a mining chip). At the same time the boiler will heat your house.
While using this boiler with 3 kW/h electricity consumption, in the end of the month you'll get around 140 dollars paycheck.
But, since it's a Smart Heat Boiler, you'll be saving your money and earn additional profits!
How To Install the Smart Heat Boiler In My House?
Our experts will help you to install, adjust and start the boiler that is suitable for your case. You will simply use the boiler while the heating element will be engaged in the calculations that compensate the cost of electricity.
What Calculations Do My Boiler Do?
Your boiler is solving the mathematical problems. These problems are produced by the Bitcoin network in order to control the bitcoin mining speed and the whole network's efficiency. The heating element of your boiler becomes a part of the network build with the same boilers. All those boilers are at our client's houses, just like yours. Thus, a powerful network with high computation power can be created, allowing you to earn extra income while the boiler is working.
What Do I Get?
You'll get a free heating, regular payouts for the computations and independence from centralized systems of heating.
Which Countries Are Supported?
We currently send the heater-miners to Ukraine, Belarus, Poland, EU, Russia and USA. If you'd like to order one but your country is not on the list, drop us a few lines so we could check if we can ship our product to you safely.


text:
Nicky has always known Russell was rich, but he has no idea how astronomically rich Russell is until his friend drops dead, on his 50th birthday, in his San Francisco mansion, with Nicky as the only witness. For 40 years the two men have kept up their friendship, with Russell's birthday offering him an annual opportunity to remind Nicky of how much more successful Russell is, and how much further he has come since their English suburban childhood. And now Nicky has come up with an uncharacteristically daring plan.
If Nicky were to become Russell and leave his old life lying dead on the bathroom floor, then he, his wife Sarah and their daughter Scarlett could start again. Only with better clothes, better hair, better stuff and a better future: everything that money can buy. Especially happiness. But when the foundations of their glittering new existence start to crack, the impact of Nicky's hasty decision begins to be felt by all those around him: by his daughter; by his own distant, confused father; by a young English woman who has come to America in search of her father, and by the mysterious Catherine, an ex-soldier who seems to take an unhealthy interest in Nicky's movements....
Sharp, funny, warm and acutely observed, Wake Up Happy Every Day is a novel about dreams and delusions, family and friendship, and what happens if you do actually find the pot of gold at the end of the rainbow.
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Just Not Good.
I just cant recommend this book to anyone. Its just not any good.
Probably not.
narrator was okay. Its the material that is not any good.
all of them.
I read a quick synopsis of this book, and bought the audible version. The premise is good - Man visits very wealthy friend, friend drops dead, man pretends to be dead friend to spend his money. Sounds good, but the story never catches, and it sadly never becomes interesting. May spends way too much time on numerous unrelated side roads, meanders from one dull topic to the next, then tries (but fails) to tie the various side roads together. Its just not good. I would have to give an overall thumbs down.
- Patrick Weldon
- Mary


text:
The people at Universum just published their 2013 World's Most Attractive Employers ranking. How do companies fare in Asia when it comes to employer of choice and employer branding? How are students selecting their choice of employers to work for?
Sony, Toyota and Lenovo were the only three Asian companies that made the Global Rankings.
- Sony managed to maintain its 9th position among Engineering students while falling three spots to 18th among Business students.
- Its Japanese counterpart Toyota kept its 45th position among the Business cohort despite taking a slight dip of three positions to 21st among Engineering students.
- Lenovo, the only Chinese company in the list, improved seven positions to reach 37th among the Engineering cohort.
Ranking Methodology
The global rankings were based on the responses of over 200,000 students from top universities in 12 countries, including Australia, China, India and Japan, who participated in Universum's annual student survey earlier this year. Through the survey, they indicated the organisations they deemed IDEAL to work for and why, as well as their career preferences upon graduation.
- Respondents acknowledge the companies they would "consider working for"
- Then select their five "ideal employers"
- The rankings, dubbed the Universum Top 100, measure the employer appeal of companies in the recruitment market.
Asia Pacific Ranking
- Countries covered in 2013: Australia, China, Hong Kong, India, Japan and Singapore
- Total number of students surveyed in 2013: 62,697 (26,246 Business, 36,451 Engineering/IT)
Here are the Top 25 Ranking in APAC
Download the Global Ranking Here.


text:
Listed 11/16/16
Open House 11/20/16
Under Contract 11/20/16
Closing in December!
Building completely renovated in 2006: all new windows, electrical, plumbing & roof. Hardwood floors throughout. Open concept kitchen/living and dining room. Kitchen features maple cabinets, granite counter tops and a spacious island with electric outlets. Frigidaire stainless steel appliances with a gas stove. Bathroom with maple vanity, granite counter top, marble floor & whirlpool tub. In-unit laundry and extra storage in the basement. Parking space included in price! 2 blocks to the Noyes EL, restaurants, and shopping, 5 blocks to Northwestern and fabulous downtown Evanston. Great as a residence or as an investment/rental property.
Property: 2147 Ridge Ave 1B
Listing Price $200,000
Ready to Sell or Buy?
Click Here to Schedule with an Agent.


text: On Beacon Hill, you can eat home-style Filipino food at brightly lit Inays (and maybe catch the servers one-person drag show). You can get really good catfish at a Shell station. You can go to family Mexican restaurant Baja Bistro (or to its everyone-welcome-especially-gays-on-Wednesdays bar). And now theres Jerry Corsos wood-fired pizza place, Bar del Corso. Jerrybeloved in Seattle cooking from his days at Cafe Lago, Harvest Vine, and Campagnelives in the neighborhood, and its a neighborhood spot: friends running into each other and sharing a table, little kids jumping up and down. The pizza is just great. (Bar del Corso, 3057 Beacon Ave S, 395-2069, 510 pm)


text:
In this episode I'm chatting with the fabulous Toni Salter, also known as The Veggie Lady.
Toni has a passion to see organic principles adopted by everyone, encouraging people to grow organic produce anywhere, whether it's in their backyard, hospital rehabilitation centre, day programs for people with disabilities or even mental health and aged care facilities.
Toni is a qualified horticulturist and has been teaching community education classes on organic gardening through local councils around Sydney since 2003.
Toni also spends her time running therapeutic gardening programs and developing sensory gardens through a number of community health organisations. She offers training on social and therapeutic gardening for staff, carers and volunteers working in aged care, mental health, disability, rehabilitation, schools or community gardens.
Toni has been a national councillor for the Australian Institute of Horticulture and is currently the President of Cultivate, the Horticultural Therapy Society of NSW.
Toni and I met online a few years ago and had an instant connection as our passions and interest are very much aligned. We're like two peas from a home-grown pod!!
Through our conversation Toni shares;
Toni also shares her top tips for starting a therapy program…
More information on Toni's personal blog and her therapeutic gardening programs, workshops and resources are available at www.theveggielady.com
Find Toni on Facebook, Twitter and Instagram.
Cultivate is the peak body for horticultural therapy in NSW, and currently located at the Telopea Centre on the campus at Ryde TAFE.
Find more information on Cath's Organic Gardening and Horticultural Therapy Programs at www.soiltosupper.com
Find Cath on Facebook, Twitter, Instagram, LinkedIn.
Thank you for joining us in The Wellbeing Garden!
Caring for our wellbeing allows us to live a healthy, happy and sustainable lifestyle.
Connecting with nature nurtures our mind, body and soul.
In this episode I'll share simple ways to enjoy gardening to improve health and wellbeing, for yourself and others.
We'll look at the health benefits from connecting with nature and the fun things you can do to nourish your body, mind and soul.
The benefits from nature and gardening range from –
Helps to reduce the severity or impact from depression. Can assist in lifting the spirit or mood in people who are feeling very low.
There's actually loads of research to back this up. Playing in the garden actually calms nerves, reduces blood pressure, decreases stress hormone cortisol and increases serotonin – the happy hormone!
Home organic grown food is packed with good health AND vitality.
Grow healthy herbs like Parsley to boost your vitamin and mineral intake or Lemon Balm to relax and relieve stress.
To harvest the amazing health benefits of gardening try a few simple ideas
If you begin each day with the belief that you'll learn, grow and thrive, you will.
For more information visit www.soiltosupper.com
Here's the links mentioned throughout the episode…
Share your abundance or connect with local growers at -
Join the Soil to Supper Club Community -
Thanks for joining me in The Wellbeing Garden.
Welcome to The Wellbeing Garden with host AND expert gardener, Cath Manuel.
In this episode I'll share my journey from working in the Horticulture industry as a consultant and educator to training as a Horticultural Therapist and how I help people improve their wellbeing through gardening and growing food.
I'll also share future episodes and how you can learn, grow and thrive with me.
For simple ideas on organic gardening and horticultural therapy visit www.soiltosupper.com
Thanks for joining me in the garden!


text:
All reviews seem negative
All reviews seem positive
Workforce Walker Personnel,LLC is locally owned and operated and here for all your staffing needs....Direct Hire,Temporary,Try & Hire,and Payrolling. We do office,administrative,professional,industrial and manufacturying staffing.
From family friendly trips with kid friendly activities to local plumbers lawyers, spas, and contractors. Judy's Book has millions of listings and reviews for the best and not so great. Whether you're looking for a specific business or just trying to discover great places we make it easy. We're a family oriented site focusing on bringing trusted reviews and recommendations to moms and others. Green and Sustainable places are becoming more relevant to Judy's Book users, have a favorite place? Write a review and tell users why it's Green!


text:
Hello All!
I'm newbie in unixes and in doubt in one question.
How we can change a euid of a process? Become a root for example.
The only possibility that i found is to exec() suid Program. Owner of the Program must be root. Is it the only way to change euid of a Program? or there is another possibility to change euid of a process to whatever i want. If so can i remove all set-uid-programs from my system? Or set-uid-programs is always the case (necessity) in all unixes?
PS sorry for my english. hope you understand the question.


text:
Epson Photo Quality Inkjet Paper A4 100 sheets
This product is not currently in stock, but is usually available from our supplier within 5-7 days of your order being placed.
An inkjet photo quality plain paper for quality printing up to 1440dpi. Ideal for business graphics, flyers and posters. More
1x Epson Photo Quality Inkjet Paper A4 100 sheets Sorry, there are no more available.
Product Specification
|Paper Finish
|Fine Art
|Paper Size
|Sheet Weight (g/sm)


text:
4th of July / James Patterson and Maxine Paetro.
Electronic resources
View other formats and editions
Record details
- ISBN: 1594832307 (sound recording : OverDrive Audio Book)
- ISBN: 9781594832307 (sound recording : OverDrive Audio Book)
- Publisher: [New York, N.Y.] : Time Warner Audio Books, 2005.
Content descriptions
|General Note:
| Downloadable audio file.
Title from: Title details screen.
Duration: 7:36:54.
|Participant or Performer Note:
| Read by Carolyn McCormick.
|Summary, etc.:
| After losing one of its own, Lindsay Boxer and the Women's Murder Club make a courageous return for their fourth and most chilling case ever -- one that could easily be their last. A young girl is killed in crossfire after a routine arrest goes terribly wrong, and Lt. Lindsay Boxer has to defend herself against a charge of police brutality. In a landmark trial that transfixes the nation, Lindsay fights to save her career and her sanity.
|System Details Note:
| Requires OverDrive Media Console (file size: 109438 KB).
Mode of access: World Wide Web.
Search for related items by subject
|Boxer, Lindsay (Fictitious character) > Fiction.
Policewomen > Fiction.
Serial murders > Fiction.
Police shootings > Fiction.
Police > California > Fiction.
Half Moon Bay (Calif.) > Fiction.
Trials (Police misconduct) > Fiction.
Mystery fiction.


text:
Three new Limited Edition Foodpacks have been added to our selection of delicious flavours just in time for the winter months…
'Back by popular demand, we have three great new editions for the winter season,' explains LighterLife's nutritionist Susannah Haynes. 'Creamy Asparagus Soup, Mint Chocolate Shake, and Apple & Cinnamon Porridge will all be available from your LighterLife Counsellor over the next few months.
'The improved Apple & Cinnamon flavour is a great way to spice up your breakfast, and the Creamy Asparagus is tasty, easy to make – as you just add water – and can be enjoyed for lunch or dinner. It's an ideal option for people on the move, living busy lifestyles. The Mint Chocolate can be served hot or cold, which will make a delicious, warming treat during the cold winter evenings.'
All LighterLife Foodpacks contain at least 25% of your recommended daily allowance (RDA) of vitamins and minerals, and are also high in protein and fibre – all you need to keep you in great health while you're on the LighterLife programme. The Mint Chocolate shake and Creamy Asparagus soup are also gluten-free and all three Limited Edition flavours are suitable for vegetarians.
To order your Limited Edition Foodpacks, contact your local Counsellor today!


text:
- HubPages»
- Sports and Recreation
Finding the Perfect Summer Camp!
It might be a little bit early to be thinking about summer camps, however at We Did It! We already have planned our camps for 2011. All the details will be available soon through our website. www.wediditkids.com. If you decide not to join us, there are several other camps in Calgary. However finding the perfect camp for your child can be a challenge as they tend to fill up really quickly.
There are several different types of camps in the city to select from.
Option 1:Multi-Sport Camps
Multi-sport camps teach children a variety of different sports. These camps are great in that they provide children with new exposure to a variety of different sports. Winsport Canada is a great example of a fabulous organization that offers weekly camps for Children between the ages of 4-13. The company has a large selection of camps that will be bound to take your camper on an adventure that they will never forget!
Option 2: Specialty Camps
Specialty Camps are specific to one particular area of interest. These types of opportunities are limitless and can range from Biking to Reading.
Option 3: Adventure Camps
Adventure Camps are wonderful in that they expose kids to a variety
physical and social activates. Such activates include: Arts and Crafts,
Games and Lessons, as well as Field Trips. The camps that will be
offered through We Did It! School-Age Society this summer are great
examples of this form of camp.
There are a number of considerations to make before making your camp selection. Cost is perhaps one of the more obvious considerations. But you also should look into the quality of the camp. Is this going to be a camp where my child will be able to learn, develop, and have fun at the same time?
As many of you are aware, there is currently a very high need for quality and affordable childcare programs in the city. Finding care in the summer can often be as challenging as finding care during the rest of the year. One of the conflicts in the city is that some of the childcare programs that are out their will choose to close their doors during the summer months. One must question why companies choose to do this as it is during the summer that the year round programs will experience the most revenue. We will be exploring the need for care in future issues. As for now, we can only encourage you to do your research early when it comes to finding the perfect Summer Camp for you and your child.
On a side note, there are no licenses required to operate a summer camp program meaning that research is a very important part of the selection process.
When selecting a camp, it is always a good idea to look for something that focuses on fun and education, and that features staff who are all qualified with at least an early childhood education.
Camps can often be a challenge to find, but persistence, awareness, and research will go a long way towards finding the perfect camp!
Ryan MacIntyre
Executive Director, We Did It! School-Age Care Society
Phone: 403-663-0742 begin_of_the_skype_highlighting 403-663-0742 end_of_the_skype_highlighting
Website: www.wediditkids.com JOIN OUR MOVEMENT TODAY!
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text:
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There aren't any tickets listed right now for Jimmy V Classic: UConn Huskies vs. Syracuse Orange & Villanova Wildcats vs. Gonzaga Bulldogs Basketball at Madison Square Garden in New York, NY on Tuesday, December 05, 2017. Sign up for an alert, and we'll let you know when tickets are available!
Note: We will NOT share your email address with any third-party vendors. For more details, see the link to our Privacy Policy in the site footer.


text:
Ingrid Mans
Project Associate
Ingrid Mans joined the Conservation Management Institute in 2010 as an undergraduate to delineate and classify wetlands for ongoing work in the National Wetlands Inventory program. After completing her Geography degree in spring of 2011, her role began to consistently expand to lead and train wetland delineators, and manage the delineation team on specific projects. Moving beyond NWI related projects, Ingrid became increasingly involved with the field biology team. As she participated in a wide variety of projects at Fort Pickett, Quantico, and the Merck propertyin Elkton, VA. She provided extra help on the groundand expertise in geospatial data management and analysis of field data. More recently, her primary projects include Rhus modeling and mapping at Fort Pickett, and forest carbon offsets in Central and South America.
Geospatial Technologies
Remote Sensing
B.A. Geography – Virginia Tech (2011)
- email@example.com
1900 Kraft Drive Suite 250
Blacksburg, VA 24061-0534
- Desk Phone: 540-231-1620


text:
Dry eyes can arise as a result of insufficient tear production, excess tear loss, abnormalities of eyelids and blinking, or changes in tear film composition. Different forms of dry eye interact with each other, creating a vicious circle. Inflammation is both a cause and a consequence of dry eye, and can have a key role in maintaining the vicious circle. Dry eye syndrome is a common condition affecting 15-33% of those aged over 65 years. Prevalence increases with age.
Dry eyes are commonly treated with non-prescription products, such as artificial tears (lubricating eye drops) and ointments. In some cases punctal plugs are applied to reduce tear fluid removal. More severe dry eyes are treated with prescription eye drops, with available options being few and with an unfavorable side effects profile.
Oculis is conducting pre-clinical studies for its dry eye candidate, OC301, which are to be completed in July 2016, with phase I and phase II pilot studies conducted in 2H 2016. Early research on OC301 is promising, indicating that the product could have benefits over already licensed alternatives.


text: This book offers a novel approach to Roman culture, looking at food as it is represented in literature. Although not generally thought of as the noblest of literary subjects, this view is a legacy from the Romans, so it is curious that Roman writers chose so persistently to depict their society at the dinner table. Why this was so, and what effect the inclusion of food had on the status of the literary texts that contained it, are among the questions discussed here. The book also addresses many of the problems that arise when a material subject is translated into words, and contains fresh interpretations of Latin texts that have been unjustly undervaluedcomedy, satire, epigrams, letters, and iambics. While often regarded as something trivial, food was in fact one of the most suggestive images for Roman civilization.


text:
For most everyday beverages, the regular cloudy white ice cubes that come from your ice cube trays or refrigerator ice-maker are perfectly fine. However, sometimes you want a fancier looking cube, perhaps for floating in a punch bowl or in highball glasses at your next cocktail party. The slower the water freezes, the less cloudy the ice cubes will be -- but using filtered or distilled water also helps with the clarity of the ice.
Step 1
Boil the filtered or distilled water in a kettle. Fill it so you can make as much ice as possible. You can filter your own water in ahome filtering device, such as a filter pitcher or faucet attachment, or simply purchase distilled water at your local grocery.
Step 2
Pour the boiling water into the silicone ice cube trays. Use silicone rather than plastic trays -- silicone is a more heat-resistant material, and boiling water can melt plastic. The boiling water slows the freezing process, and this combined with the filtration process allows the ice to release any trapped air bubbles, which are the main cause of the cloudiness of regular ice.
Step 3
Place the trays in your freezer and allow to freeze.


text: Where and how? title says it all, wanting to sell social boost things like twitter and youtube S***! Also how could i drive traffic after making the website? I know i can ping the website i.e... so where may i read up on how to drive traffic to your website. I'll gladly invest in any way as im hooked onto this idea. Already making £5-$10 weekly on fiverr clone sites but i want to maximise my earnings in another way! Please help! Best regards


text:
Warning: This article contains spoilers from Season 7 of Showtime's Shameless.
Shameless is definitely having one of it's better seasons this year with its much earlier than usual seventh outing. The storylines are as wacky as ever as Frank replaces his family with a group of homeless. Although the comedy is in full flow, there has also been a lot of self-betterment this season with Carl enrolling at military school, Fiona taking control of her life and Ian learning more about sexuality. Season 7 has certainly went back to basics.
With the majority of the Gallaghers now living under one roof, the struggles still continue for America's most shameless family and it's certainly still entertaining to watch. There was a lot happening in this week's installment as Frank's reign of the homeless shelter came to an end and Carl embarked on a new chapter as he left for Military school. Let's take a look at several under the radar things from Season 7, Episode 2 "The Defenestration of Frank."
1. History Is Repeating Itself...
We're used to seeing Frank getting kicked out of the house but it's always been the Gallagher family doing the kicking. This time around, Frank's new family of worked out that he was keeping most of the profits they made and in an act of revenge, they threw him out of the upstairs window, injuring the absentee father. I can't say I blame them really.
After seven year's Frank still falls into the same patterns, making the same mistakes time and again. Considering all of the times he found himself out on the streets you'd think he would have learned his lesson by now — clearly nor. It looks like Frank just lost another family — I wonder what ludicrous journey he will embark on next?
2. ...In More Ways Than One
I've commented on Lip's downfall before but there was one scene in the latest episode where the similarities between him and Frank were rather disturbing. It was the scene where Lip and Joaquin decided to toast their hacking victory over a few beverages — that in itself is an issue because Lip shouldn't be drinking considering he's only just out of rehab.
Before taking a drink, Lip went on a rant about how his hacking was doing the world a favor as it would help in taking down a corporate company. He then bought everybody in the Alibi a drink. This is oddly similar to the way Frank often plays to the crowd of the Alibi and it certainly marks another terrifying chapter in Lip Gallagher's descent. Frank would be proud.
3. Warring Siblings (Again)
Fiona and Lip have been at each other's throats more times than I care to count but the animosity between the pair in the latest episode was off the chart. The healthy sibling rivalry that began with the Season 7 premiere has found itself turning into a full blown disagreement and Fiona can't deal with Lip's lack of appreciation for her continuous sacrifices.
Whether or not we'll find them on the same page again this season remains to be seen but their on/off again relationship is extremely realistic —brothers and sisters disagree in real life all the time — it happens — and I think it's rather awesome that Shameless isn't afraid to show that on a regular basis.
Are you a fan of Shameless? Be sure to check out these:
- What To Expect From Season 7 Of Showtime's Shameless
- Shameless Seasons 5 And 6 Are On Netflix — Here's Why You Should Be Binging
- Shameless US and 4 Other TV Remakes That Challenge Their Original
4. We've Been Here Before
It's rather ironic that after all the genuine hard work that Frank did for his new family, he winds up back on the street again. This time, an injured Frank found himself sleeping on a damp park bench and as much as I hate to say it, I actually felt a little sorry for him.
Nevertheless, there's no denying that we've seen this scene a thousand times before, but will we see it again? I guess we'll have to see what Frank Gallagher has up his sleeve in the next few episodes. He won't be down for long.
5. It's Not All Fighting
Ever since the Gallagher siblings grew up they've embarked on their own storylines and that means that we see less and less of them in the same place at the same time. The scene in Fiona's bedroom was very nostalgic and reminded fans that even though Shameless has had to move in new directions, it's still capable of giving us heart-felt familial moments from TV's greatest family.
Fiona also felt more like her original self — this new self-improved Fiona has shown little regard for her siblings recently so I was happy to see that maternal element back in the show again. I really hope we see more moments like this throughout Season 7. They're nice rarities in the show considering everyone is currently fighting with each other.
6. Ian's Changing Views
Shameless has done a great job at educating viewers of the show about transgender issues but I think the most notable thing about Trevor's storyline on the show is that it's really changing the way that Ian sees the world. I loved that scene with Fiona, Ian and Lip discussing what was going on in each other's lives and Ian jumped to Trevor's defense when Lip made an uneducated remark about Trevor's gender.
I feel like this whole storyline has opened Ian up a lot more — it's helped him realize that there is a whole world beyond the South Side of Chicago. I applaud the Shameless writers for doing this storyline and I find Trevor to be a much better love interest for Ian than Caleb ever was.
7. How Much Do We Really Know About Svetlana?
Due to the brilliant Isidora Goreshter being made a series regular for Season 7 there has been plenty of screen time for Svetlana this season — she is one of the show's best characters. However, her storyline this week, mixed with some of the rather odd statements she's made in previous episodes, really got me thinking about the character and in reality how little we actually know about her.
There have been references about her homeland in the past, but the reality of the situation is that Svetlana is a pretty remarkable person to be so content and happy in life after such a tough upbringing. Her revelation about Yvon does raise eyebrows though, what else could she be hiding that we don't know about? Anything is possible and with a little luck it'll lead to a hell of a lot more brilliant one-liners.
Check out a preview for next week's episode:
I hate to say this but we're officially half way through Season 7 of Shameless. We'll leave the in detail reflecting until the season culminates but so far the Showtime dramedy has done a great job at re-inventing itself and managing to stay original. With so much still to look forward to, including Fiona's new venture, Franks' next move and the return of everybody's favorite #TV bad boy Mickey Milkovich, it looks like Shameless is going to get even better.
Shameless airs Sundays on Showtime. Did you notice anything important in the latest episode of Shameless? Tell me in the comment section below.


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Going into the Savannah Swim Team Winter Classic this weekend, Jack Deal of the Charlotte Swim Club could be described as two things.
Unshaven and untapered.
The 17-year old had not slowed down his training, and he still had the facial and body hair that cost swimmers precious hundredths of seconds in the water.
Turns out, Deal wouldn't need any of those extra seconds. When he left the Chatham County Aquatic Center Sunday night, only one "un" applied.
Deal owned the boys' senior (18-and under) division, winning all nine of his events each in meet record time. Not bad for a tired, fuzzy young swimmer battling a sinus infection.
"He was really hot out there this weekend," Charlotte coach Doug Fleck said. "I guess you could say that he must have ate his Wheaties before coming down here."
Deal's fond memories of the Chatham County Aquatic Center just got even more special. The Aquatic Center was where he earned his first Junior National Cup, and his showings in the pool this weekend were enough success to send an entire swim team home to Charlotte smiling.
"This pool has really been good to me, and now this happens," Deal said. "I'd been looking forward to coming back down here to swim for a long time."
Deal's overall performance was the show-stopper of the meet, but he was outdone a bit by the meet's workhorse, 12-year-old Julie Richards of the Brunswick Y Swim Team.
Richards will need her own U-Haul to take all the hardware she won back to Brunswick, winning seven of the 11 events she competed in. The four events she didn't emerge from the pool victorious resulted in two seconds, a third and a sixth.
"Julie's a hard worker. She deserves all the successes that come her way," Brunswick coach Stephen Andreades said. "On top of being talented, she prepares very hard. That's a winning combination."
Richards earned the highest cumulative point score out of the 391 athletes entered in the three-day event, totaling 85 points. The soon to be teen-ager relished her last weekend competing in the 12-and under division.
"Eleven swims in three days in really, really hard," Richards said. "By the last one, you just hope you don't die a slow death out there in the water."
Richards still had enough left in her tank to best her seeding time in the 1650-yard freestyle by almost 49 seconds, for her seventh and final first- place trophy of the weekend.
Twelve-year old Bryce Roberson had the most rewarding weekend out of the 87 local swimmers in the event. The Savannah Swim Team member totaled 75 points in 10 events, winning four events and setting three meet records.
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Tally.ERP 9 Tally Customization Tally AMC Tally Training CCTV, Networking, Computer Services, Customized Software, HR, Payroll
JDS Solutions is a consortium which endows with novel IT solutions that are inventive and trendy. It is a unit with worldwide clients which includes leading organizations across private and social sectors. Established in the year 2000 with a target to deliver the best in IT industry, its strong ethical values and skilled expertise has facilitated JDS Solutions to grow at a rapid rate. Our clear approach towards application development, maintenance and management service is what makes JDS Solutions unique from others. Our unit is committed to discover the formula to help our clients to deliver more and this helps us to move ahead with flying colors.
Best Software
August 04, 2016


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Services power our industry, and accordingly we have a wide range of membership benefits which will help you make the most out of your membership. Network with industry peers and further the reach of your organisation through the vast array of available EVCOM member channels.
Marketing and Business Development
- Listing on the EVCOM web site
- Free job vacancy advertising on the EVCOM website
- The use of the EVCOM member logo on all marketing material
- The opportunity to contribute towards articles in the business and trade media on issues facing our industry – raising your profile as a thought-leader in the industry
- Benefit from EVCOM's strategic alliances with other professional associations
- Access to specialist services – eg. legal and VAT helplines
- Discounted member rates for profiled buyer data
- Raise your profile by supporting EVCOM activities, publications, and research
- Increased visibility and reduced rates at tradeshows
- Access to the members only section of the website
- Participation in overseas market exploration and trade development missions
Education, Training and CPD
- Opportunities to attend, network and/or host exclusive industry events
- Reduced rates for all staff at EVCOM training & educational events
- More
Access the latest industry information and research
- Reduced rate for The UK Events Market Trends Survey
- Latest industry research & reports, factsheets and updates on regulatory and legislative issues
- Support with guidance on good practice in procurement
Regulation and Representation in government on issues affecting our industry
- Representation in government
- Monitoring and guidance on new legislation via the EVCOM Regulation committee
- Representation on the Business Visits & Events Partnership
- The Tourism Alliance lobby on EVCOM's behalf with direct connection to the Minister of Tourism and other high level government officials
- All Party Parliamentary Groups (APPGs)
Access toolkits, guides and industry standards
- CSR toolkit with information on how to run more sustainable events and businesses
- An easy step by step guide to BS8901
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Corporate Social Responsibility initiatives
- We lead the way with our sustainable and environmentally friendly approach to our industry. We provide regular workshops and seminars on the reduction of waste, on social responsibility and on respectful use of resources. More on Corporate Social Responsibility
Committees (members only)
EVCOM has working committees covering key areas such as: Education, CSR, Regulations and Representation, Membership and Awards. Each committee is led by an EVCOM board member and supported by various industry professionals. These are complemented from time to time by adhoc specialist groups.
This and much more is available for you as Production Company or Agency. EVCOM is here to support the industry, ensure the success and sustainability of our industry as communication experts.


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About David Moore
Live A Better Story.
First of all, that is NOT me in the picture above. However, I vividly remember one very similar hanging in my parents bathroom when I was a kid. It was incredibly embarrassing and I would beg them to take it down. They eventually did but I was scarred for life. To this day, I still don't go naked in public.
So from nude modeling to legal printing is quite a big jump. So here's my story.
The Entrepreneur
I've pretty much always had an entrepreneurial spirit. I was always the kid who put up the lemonade stand first and had my friends work for me. But I also hustled True Grit magazine (you're old if you remember that) and I had a newspaper route. Seasonally, I would try my hand selling door-to-door products such as: flower seeds, Christmas wreaths and greeting cards.
College Days
In college, a partner and I capitalized on the NC State Basketball 1983 National Championship. We created, designed and sold "Cardiac Pack" foam can huggers to major convenience stores and drug stores in the Raleigh area. I think we marked up the huggers .10 to Kerr Drugs just so we could walk into the store and look at them and say, "We did that".
I was also exposed to the printing industry while in college. I had a part-time job at a small commercial printer in downtown Raleigh. So I've sort of been in "in the industry" since around 1982.
The Beginning
The origins of Advantage begin around 1982 as well in downtown Kinston, NC. Over the years it grew and swallowed up struggling printers until there were only two major printers in Kinston. With Advantage being the smaller and more of a boutique firm.
The CEOwner
I joined Advantage in 2008 as a partner and then bought 100% ownership in 2010. And it was this culture of "specialization" in a boutique firm that led me to focus on printing for the legal industry.
Legal Printing Specialist
Heavily influenced by one of our long-time clients, White & Allen, I felt life would just be more enjoyable if I could serve more clients just like them. We had a significant portion of our revenues from the professional and legal industry, so focusing on serving small to mid-sized legal firms was an easy choice.
APGLEGALPRINT.com is the legal printing division of AdvantgePrintGroup and is where I focus my energy.
Fun Facts
- I was a band geek in Jr. High School
- I've broken my nose twice playing baseball in High School
- I used to race motocross
- I won the 1986 Mr. North Carolina Bodybuilding Championship - Middleweight Division.
- I am a passionate Landscape and Nature photographer and sold my first print in 2013.
- I am an Army brat spending the first 16 years of my life on a military base
- I was an All-Conference wrestler in high school
- I've had three (3) Holes-in-One with best round of golf - 74 at Wilson Country Club, 1990


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what's a typical breakfast?
What's a typical breakfast for you?
For your kids?
me - two pieces of toast with marmite or vegemite.. and a cup of coffee
Gaby - one piece of toast with marmite, peanut butter, jam, or peanut butter & jam, and a glass of water...
Re: what's a typical breakfast?
For me - It depends. On days I go to school it's either just juice, or juice, a banana and toast, or cereal. When I'm home for the day, usually cereal or an egg and cheese sandwich.
Kids - They get to pick each day. Either cereal, waffles, pancakes, eggs, or fruit and toast.... and juice.
Re: what's a typical breakfast?
Bowl of cereal or one of those mini boxes of cereal.
Sometimes waffles or bagels or a Fiber One breakfast bar.
Just depends on everyones mood what they have.
Re: what's a typical breakfast?
me- french vanilla yogurt with maple granola, cup of coffee
lexi- whole wheat toast with butter, or peanut butter.. sometimes fruit, and water
Re: what's a typical breakfast?
Either cereal of toast and a cup of tea here. Even for Jassie.
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Captive Beauty Trailer (2011)
01 January 2011
Documentary - CAPTIVE BEAUTY is a feature documentary about four female inmates and a surreal beauty pageant inside Medellan, Colombia's all female prison. It's an intimate tale of the women's crimes, their childhoods, and a unique search for redemption. -
Watch the official Captive Beauty 2011 trailer in HD below or find more Captive Beauty videos on Vidimovie.


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The NFκB-signaling pathway regulates cell proliferation and inflammation. Activation of the pathway is implicated in the etiology of colorectal cancer (CRC). NSAIDs may reduce CRC risk partially through a nuclear factor-kappa B (NFκB)-dependent pathway. In this study, we investigated associations between 34 NFκB1 and 8 IκBKβ tagSNPs and CRC risk and examined interactions with non-steroidal anti-inflammatory drug (NSAID) use. Using conditional logistic regression, we investigated these associations among 1584 incident CRC cases and 2516 sibling controls from the Colon Cancer Family Registry. Three IκBKβ SNPs were associated with a statistically significant lower colorectal or colon cancer risk: rs9694958 (A>G intron 5) (colorectal: ORhzv = 0.26(0.07–0.99), Ptrend = 0.048, Padj = 0.25), rs10958713 (A>C intron 19) (colon: ORhzv = 0.62(0.42–0.92), Ptrend = 0.005, Padj = 0.03) and rs5029748 (C>A intron 2) (colon: ORhet = 0.72(0.56–0.91), Ptrend = 0.01, Padj = 0.08). We replicated trends associated with NFκB1 and IκBKβ variants identified in a previous study (rs4648110 (T>A intron 22), rs13117745 (G>A intron 5) and rs3747811 (T>A intron 1)). IκBKβ's rs6474387 (C>T intron 20) and rs11986055 (A>C intron 2) showed substantially lower colon cancer risk among current NSAID users (Pinteraction = 0.01 and Pinteraction = 0.045, respectively), whereas NFκB1's rs230490 (G>A 5ʹ (outside UTR)) and rs997476 (C>A 3ʹ (outside UTR)) showed higher CRC risk among current NSAID users (Pinteraction = 0.01 and Pinteraction = 0.03, respectively). These findings suggest that variants in NFκB1 and IκBKβ are associated with CRC risk and NSAIDs may function partially through an NFκB-dependent pathway. The SNPs identified here should be considered for future functional studies and may be useful in designing a pharmacogenetic approach to preventive NSAID use.
Results from epidemiologic and experimental studies have pointed to chronic inflammation as an important cause of colorectal cancer (CRC ) (1–3). The exact mechanism(s) through which inflammation contributes to CRC etiology and the extent to which inflammation differentially impacts colon and rectal cancer etiology are still being investigated (4); however, growing evidence suggests that one relevant mechanism is the nuclear factor-kappa B (NFκB)-signaling pathway (5). The NFκB signaling pathway regulates cell proliferation, apoptosis and inflammatory responses, through activation of an ubiquitous transcription factor, NFκB (5). Constitutive activation of NFκB has been observed in 40% of CRC tissues and in 67% of CRC cell lines (6).
NFκB is found as a homo- or heterodimeric complex (7). The most commonly studied NFκB complex is the RelA:p50 heterodimer (8). In the cytoplasm, RelA:p50 is normally bound to an inhibitory protein, IκBα, rendering the transcription factor inactive. In response to a wide array of stimuli, including proinflammatory cytokines and chemokinase, the IκB kinase (IKK) complex phosphorylates IκBα, causing degradation of IκBα and activation of NFκB. Once activated, NFκB translocates to the nucleus where it binds to the promoter region of its target genes (5,7). The IKK complex is composed of two catalytic subunits, IKKα and IKKβ, with IKKβ required for activation of the RelA:p50 dimer (5). The NFκB1 gene encodes p50 and the IκBKβ gene encodes IKKβ. Initial studies have suggested that genetic variability in NFκB1 and IκBKβ is associated with CRC risk (9,10) and that genetic variability in IκBKβ is associated with CRC survival (11).
Several studies, including randomized trials, have shown that the regular use of non-steroidal anti-inflammatory drugs (NSAIDs) is associated with decreased CRC incidence and mortality (12–14). Reduction in inflammation by NSAIDs is generally attributed to inhibition of prostaglandin synthesis (3,15), but there is evidence that several NSAIDs, including aspirin, also inhibit NFκB activation (16,17) and induce CRC cell apoptosis through an NFκB-dependent mechanism (18–20). Thus, it is biologically plausible that variation in NFκB signaling pathway genes, including NFκB1 and IκBKβ, modify the inverse association between NSAID use and CRC risk.
We have shown previously that genetic variability in prostaglandin synthesis and inflammation can influence risk of CRC (21–26). The purpose of this study was to investigate the association between genetic variability in NFκB1 and IκBKβ and risk of CRC and to investigate the interaction between genetic variability in NFκB1 and IκBKβ and NSAIDs on the risk of CRC using a case–unaffected sibling control design in the Colon Cancer Family Registry (CCFR).
The study population has been described previously (27). Briefly, CRC cases were recruited for the CCFR from six registry centers. The CCFR cases were probands and affected relatives diagnosed with primary invasive CRC from 1998 to 2002 who were interviewed within 5 years of diagnosis. Controls were siblings without a CRC diagnosis at the time of ascertainment. Although eligibility requirements varied slightly, registry centers typically required participants to be between the ages of 20 and 74 (27).
Standard questionnaires were used to collect epidemiologic data from CCFR study participants regarding demographic characteristics, medical history, NSAID use, family history of cancer, smoking history, diet, physical activity, height and weight. Regular NSAID use was defined as use two or more times per week for at least 1 month. Current NSAID use was defined as regular use in the 2 years prior to study enrollment. Blood and tissue samples were collected according to standardized procedures. Individuals were excluded from this study if the case did not have at least one matched unaffected sibling as a control and if an individual's sex determined by genotyping did not match reported sex on the questionnaire. Only self-reported Caucasian study participants, ascertained through population-based recruitment, were included in this analyses (sample sizes among other racial/ethnic groups and clinic-based populations were too small to assess associations).
Informed consent was obtained from all participants. The Institutional Review Boards at each CCFR site approved the study.
A list of SNPs examined in this study can be found in Supplementary Table 1, available at Carcinogenesis Online. The procedure for tagSNP selection for the parent study has been published previously (28). Briefly, tagSNPs for NFκB1 (n = 42) and IκBKβ (n = 10) were selected using Haploview Tagger (29) with the following criteria: minor allele frequency (MAF) >5%, pairwise r 2 of >0.95 and distance from closest SNP of >60 base pairs (bp). The 5′ and 3′ untranslated regions (UTR) for each gene were extended to include the most up- or downstream SNP within the linkage disequilibrium (LD) block (~10kb upstream and 5kb downstream). In regions of no or low LD, SNPs with a MAF >5% at a density of ~ 1 per kb were selected from either HapMap (29) or dbSNP (30). The tag SNPs included two non-synonymous SNPs each from NFκB1 and IκBKβ.
DNA was extracted from peripheral blood leukocytes, and genotyping was performed at Translational Genomics Institute (TGen, Phoenix, AZ). SNPs were genotyped on the Illumina 1536 GoldenGate platform (31). Quality control checks were based on Illumina metrics, as described previously (32). Three SNPs (rs4648099, rs6813322 and rs6474387) that were not successfully genotyped on the Illumina platform were genotyped using Sequenom's iPLEX Gold (Sequenom, Inc). Five percent of the samples were re-genotyped to assess reliability. Concordance among duplicates was >99.8% for all SNPs. SNPs were excluded if the Hardy–Weinberg equilibrium P value among controls was <0.0001 or the call rate was <85%. The two non-synonymous SNPs from IκBKβ, rs2272763 and rs17875749, were excluded from analysis because they were not encountered in our population. From NFκB1, eight SNPs were excluded: two SNPs were not in Hardy–Weinberg equilibrium (including one non-synonymous SNP, rs4648099), and six SNPs were in LD (r 2 > 0.90) with another SNP with nearly identical genotype frequencies. After these exclusions, eight IκBKβ SNPs and 34 NFκB1 remained for analysis (Supplementary Table 1, available at Carcinogenesis Online).
Single SNP main effects. Conditional logistic regression was used to estimate odds ratios (OR) and 95% confidence intervals (CI). A variable that indicated unique sibling kinships was used as the matching variable, and models were adjusted for age and sex. For each SNP, the risk of CRC was estimated using a codominant model, unless any cell had fewer than five individuals, in which case a dominant model was used. A global P value (two degrees of freedom for codominant models), determined using the likelihood ratio statistic, was used to test for differences between carriers of the variant allele and homozygous carriers of the wild-type allele. A trend test was performed using the log-additive model to determine if there was a dose-dependent association with the variant allele.
Interaction analyses. Conditional logistic regression was used to investigate the interaction between SNPs and current NSAID use, as well as between SNPs of NFκB1 and IκBKβ. OR estimates and 95% CIs were calculated for each combination of genotype(s) and/or NSAID use status (current or former/never). In this study population, current NSAID use was more strongly inversely associated with CRC risk than other aspects of NSAID use and thus we chose it as the primary variable for interaction analysis. The reference groups were composed of individuals who were homozygous for the wild-type allele(s) and never/former users of NSAIDs. Because use of NSAIDs may be associated with other known risk factors for CRC, NSAID interactions were adjusted for smoking (continuous pack-years), body mass index (BMI) (continuous) and physical activity (four-level ordinal variable based on average MET hours) in addition to age (continuous) and sex. For SNP-SNP interactions, only SNPs independently associated with CRC risk (global P < 0.05) were combined with the other SNPs in this study to create composite genotypes. To avoid small cell counts, only the dominant model and composite genotypes that represented at least 5% of the population were examined. The likelihood ratio test compared models with and without the multiplicative interaction term(s) to determine if an interaction was statistically significant (Pinteraction). All tests of statistical significance used a two-sided P value and α = 0.05. Analyses were carried out using SAS v.9.3 (SAS Institute Inc, Cary, NC).
Multiple testing corrections. The correction method for multiple correlated tests developed by Conneely and Boehnke was used for main effects analyses (33). P values adjusted for correlated tests are referred to as Pact, with Pact < 0.05 considered statistically significant. All P value adjustments were conducted in R (version 2.14.1). The more conservative family wise error rate methods of multiple testing corrections often prevent the detection of true associations. Thus, the false discovery rate (FDR) control method developed by Benjamini and Hochberg (11,34,35), was used to identify SNPs noteworthy at the 25% FDR levels for both main effect and NSAID interaction analyses. Tables II andIII include only SNPs that had a significant global P, Ptrend or Pinteraction value or were noteworthy by FDR.
We used this study to attempt replication of the results of Curtin et al. (9). (the only other study to examine the association between genetic variation in these genes and colorectal cancer using a tagSNP method). Curtin et al. examined the association between individual or composite genotypes of NFκB1 and IκBKβ SNPs and colon or rectal cancer adjusted for age, sex, center and race under the additive, dominant and recessive models. In the replication analysis, only ORs and 95% CIs are presented for individual genotypes or composite genotypes, as these were the parameters reported by Curtin et al. (9).
Characteristics of the study sample are presented in Table I. There were no obvious differences between cases and unaffected sibling controls by age, regular NSAID use, pack-years of cigarette smoking and physical activity or BMI. Cases were more likely than controls to be male.
Among the tagSNPs in IκBKβ, one SNP was associated with lower CRC risk, before corrections for multiple testing (Table II). Individuals with the homozygous variant genotype of rs9694958 (A>G intron 5) had an almost 4-fold lower CRC risk than individuals homozygous for the wild-type allele (ORhzv = 0.26, 95% CI 0.07–0.99, global P = 0.048, Pact = 0.25).
After stratifying by tumor subsite, two SNPs in IκBKβ were statistically significantly associated with lower colon cancer risk (Table II). Carriers of rs10958713 (A>C intron 19) had 1.4- to 1.6-fold lower colon cancer risk (ORhet = 0.73, 95% CI 0.57–0.92; ORhzv = 0.62, 95% CI 0.42–0.92, global P = 0.02, Pact = 0.09). The variant allele showed a dose-dependent association, which remained statistically significant after correction for multiple testing (Ptrend = 0.005, Pact = 0.03). Carriers of rs5029748 (C>A intron 2) had a 1.4-fold lower colon cancer risk (ORhet = 0.72, 95% CI 0.56–0.91; ORhzv = 0.72, 95% CI 0.44–1.18, global P = 0.02, Pact=0.11). The variant allele showed a dose-dependent association (Ptrend = 0.01, Pact = 0.08). The rs5029748 and rs10958713 variants were noteworthy at the 25% FDR level for associations with colon cancer risk; thus the chance that these SNPs are truly associated with risk is ~75%.
No tagSNP in IκBKβ had a statistically significant association with rectal cancer risk. The complete analysis of the associations between SNPs in IκBKβ and colorectal cancer is presented in Supplementary Table 2, available at Carcinogenesis Online.
No SNP in NFκB1 was statistically significantly associated with risk of colorectal, colon or rectal cancer and no SNP was noteworthy by FDR. Individuals carrying one copy of the single non-synonymous SNP in NFκB1, M507V (rs4648072), showed a reduced, but statistically non-significant, risk of CRC (ORhet = 0.62, 95% CI 0.24–1.60, global P = 0.50). The rs10489113 variant allele (A>G 3′ outside UTR) had a dose-dependent association when the analysis was restricted to colon cancer, prior to correction for multiple correlated tests (Ptrend = 0.04, Pact = 0.48) (Table II). Individuals homozygous for this variant allele had an ~2-fold lower risk of colon cancer (ORhzv = 0.53, 95% CI 0.29–0.97). The complete analysis of the associations between SNPs in NFκB1 and colorectal cancer risk is presented in Supplementary Table 3, available at Carcinogenesis Online.
We did not observe any statistically significant interactions between SNPs (data not shown). Of the three SNPs independently associated with CRC and, therefore, potentially eligible for this analysis, rs9694958 was not included because individuals with the risk-associated genotype represented <5% of the population.
Current NSAID use was associated with a statistically non-significant reduced CRC risk in the study population (OR = 0.87, P = 0.13). Two SNPs in IκBKβ, rs6474387 (C>T intron 20) and rs11986055 (A>C intron 2), altered the association between NSAID use and colon cancer risk (Table III). Current NSAID users who carried the rs6474387 variant allele had statistically significant lower risk of colon cancer (OR = 0.38, 95% CI 0.16–0.86), which was not observed in current NSAID users who did not carry the variant allele (Pinteraction = 0.01). The interaction between rs11986055 and NSAID use was similar (LD r 2 between rs6474387 and rs11986055 was 0.50); only current NSAID users who carried the variant allele had lower colon cancer risk (OR = 0.47, 95% CI 0.17–1.13, Pinteraction = 0.045). FDR analysis identified the interactions for both rs6474387 and rs11986055 as noteworthy at the 25% level when the analysis was restricted to colon cancer. There were no statistically significant or noteworthy interactions between IκBKβ SNPs and NSAID use for rectal cancer.
For the non-synonymous SNP in NFκB1, M507V, there was no statistically significant interaction with NSAID use. Two other tagSNPs in NFκB1, rs230490 (G>A 5′ outside UTR) and rs997476 (C>A 3′ outside UTR), were associated with a statistically significantly altered association between NSAID use and CRC risk (Table III). Among individuals with the homozygous wild-type and heterozygous genotypes of rs230490 current NSAID use was associated with lower CRC risk; however, among individuals with the homozygous variant genotype current NSAID use resulted in a trend toward higher CRC risk (OR = 1.29, 95% CI 0.82–2.03, Pinteraction = 0.008). The interaction between rs230490 and NSAID use remained statistically significant when the analysis was restricted to rectal cancer risk, but not for colon cancer risk. There was also a nominally significant SNP-NSAID interaction for rs997476, with higher CRC risk among carriers of the variant allele who were current NSAID users (OR = 1.57, 95% CI 0.99–2.48) (Pinteraction = 0.03).
Table IV compares the findings of this study with the previous study by Curtin et al. of genetic variability in IκBKβ and NFκB1 and the risk of colon and rectal cancer (9). Curtin et al. identified three individual genotypes and one composite genotype of IκBKβ and NFκB1 that were each inversely associated with colon cancer risk. We also observed trends toward a lower risk of colon cancer for the same genotypes. The >30% reduction in risk associated with homozygous carriers of NFκB1's rs4648110 variant allele (T>A intron 22) was nearly identical between the two studies under both the additive and recessive models of inheritance (recessive model: ORCurtin = 0.66, 95% CI 0.45–0.96 versus ORCFR = 0.65, 95% CI 0.37–1.13). The composite genotype composed of IκBKβ's rs3747811 (T>A intron 1) and NFκB1's rs4648110 was also associated with nearly identical lower risk estimates (ORCurtin = 0.54, 95% CI 0.34–0.87 versus ORCFR = 0.56, 95% CI 0.28–1.12).
Curtin et al. also identified four individual genotypes of NFκB1 and one composite genotype of IκBKβ and NFκB1 that were associated with rectal cancer risk. Carriage of the rs13117745 (G>A intron 5) variant resulted in a trend toward higher rectal cancer risk in both studies under the additive model (ORCurtin = 1.69, 95% CI 0.93–3.07 versus ORCFR = 1.22, 95% CI 0.65–2.26). The risk estimates for the remaining SNPs were not replicated.
We identified three SNPs in IκBKβ that were statistically significantly associated with lower colorectal or colon cancer risk. In addition, we report similar trends in risk estimates for many of the IκBKβ and NFκB1 SNPs identified by Curtin et al. (9). These findings contribute to the evidence that variation in IκBKβ and NFκB1 is associated with CRC risk. The activation of NFκB is a key survival mechanism of premalignant cells because it can block apoptosis by regulating anti-apoptosis proteins (36) and inhibit accumulation of reactive oxygen species (37). Furthermore, the NFκB transcription factor induces expression of cytokines and chemokines, which help sustain an inflammatory state known to contribute to colorectal carcinogenesis (1,5,38). Although the functions of many of the tagSNPs identified here are not established, if these polymorphisms directly or indirectly modify the activation of this key transcription factor, this may explain their observed associations with CRC risk.
Evidence from this study and previous studies suggests that variants in IκBKβ are associated with a lower risk of CRC, particularly colon cancer. All statistically significant or noteworthy genetic variation in IκBKβ identified here and by Curtin et al. trended toward a lower risk of colon cancer (9). The two intronic tagSNPs that had statistically significant associations with lower colon cancer risk in this study, rs5029748 and rs10958713, have no known functional impact, but have been previously associated with risk of colorectal neoplasia (9,39): in a case–control study of metachronous colorectal adenoma risk, rs10958713 was independently associated with a 36% (95% CI 13–54%) lower risk (39) and carriers of the rs5029748 variant allele who also carried polymorphisms in NFκB1 and IL6 had an 80% (95% CI 33–94%) lower risk of colon cancer (9). It seems plausible that variation in IκBKβ could negatively affect the function or expression of the cognate protein, IKKβ, thereby impairing NFκB activation and the resulting inflammation. Reduced levels of inflammation reduce risk of CRC (1,2) and this particular mechanism may have a stronger impact on colon than rectal cancer. A similar mechanism may also operate with regard to survival, as genetic variation in IκBKβ has also been associated with increased CRC survival among CCFR cases (11).
Contrary to previous studies (9,10) we did not observe statistically significant associations between NFκB1 SNPs and CRC risk. The non-synonymous SNP, M507V, was associated with a 40% reduced risk in heterozygous individuals, but this was not statistically significant (M507V has no demonstrated functional impact and is predicted to be functionally tolerable by SIFT (Sorting Tolerant From Intolerant) software (40)). In the Curtin et al. study, individual SNPs in NFκB1 were mainly associated with the risk of rectal cancer; the only SNP associated with both colon and rectal cancer risk modified the risks in opposing directions (9). The associations in this study may not have reached statistical significance because family based study designs have lower power to identify main effects (41) and because of the limited number of rectal cancer cases in our study population. Additionally, if variation in NFκB1 modifies the risk of colon and rectal cancer in opposing directions, the associations could have counterbalanced each other in analyses of CRC.
This study replicated several of the colon and rectal cancer risk estimates associated with variation in NFκB1 and IκBKβ identified by Curtin et al. (9). In both studies, rs4648110 of NFκB1 was associated with a ~35% decreased risk of colon cancer on its own and, when combined with rs3747811 of IκBKβ, a ~45% decreased risk. Using the UCSC Genome Browser (http://genome.ucsc.edu/), we found that rs4648110 is located in a potential enhancer site (42). Another NFκB1 SNP, rs13117745, which is in moderately high LD with rs4648110 (r 2 = 0.71), also had replicated trends across the two studies; carriers of the variant allele had similar lower colon cancer risk and higher rectal cancer risk in the two studies. Opposing risk effects for colon and rectal cancer were also observed with rs10489113 of NFκB1 in this study. NFκB1 is not the first gene to be identified to have opposite associations with colon and rectal cancer (43–45). Colon and rectal cancers probably have distinct (as well as overlapping) etiologies (46,47) and these findings suggest that NFκB, and the inflammation that results from its activation, may impact colon and rectal cancer carcinogenesis differently.
The findings here are a preliminary step toward a pharmacogenomic approach to NSAID use. Although NSAID use is known to decrease risk of CRC, NSAID use brings potentially serious gastrointestinal toxicity and bleeding (3,14,15,48). Therefore, it would be valuable to identify individuals with altered benefit from NSAID use to ensure that any potential harm is well outweighed by the benefits. In this regard, polymorphisms such as rs6474387 and rs11986055 in IκBKβ may be of particular importance because they interact with NSAIDs such that carriers of the minor allele have a statistically significantly lower risk of colon cancer, whereas carriers of the wild-type allele did not have decreased risk with NSAID use. We also observed a very strong pharmacogenetic interaction for NFκB1 rs230940 (P = 0.008). This SNP definitely should be followed up in other studies. Recent findings have indicated that non-aspirin NSAIDs may be less protective than aspirin itself against rectal cancer (49); therefore, individuals with genotypes known only to only increase rectal cancer risk should not be prescribed non-aspirin NSAIDs as preventative treatment.
Most studies point to the inhibition of the cyclooxygenases (COX-1 and COX-2) in the prostaglandin synthesis pathway as the main mechanism by which NSAIDs reduce inflammation and risk of CRC (3,15,50). However, current research also points to inhibition of the NFκB-signaling pathway as a mechanism through which NSAIDs may reduce CRC risk by reducing inflammation and promotion of apoptosis (18–20). Indeed, we observed statistically significant interactions between genetic variation in IκBKβ and NFκB1 and NSAID use, which is further evidence of a link between NSAIDs and the NFκB-signaling pathway. There are indications that some NSAIDs, including aspirin, directly impact the function of IKKβ in vitro (the protein encoded by IκBKβ) by competitively interfering with ATP binding (17). It is possible that variation in IκBKβ could affect the binding of NSAIDs to IKKβ, providing an explanation for the interaction between variation in IκBKβ and NSAID use. The fact that variation in both IκBKβ and NFκB1 interacted with NSAID use to modify CRC risk serves as further evidence for including the NFκB-signaling pathway in future studies of the chemopreventive effects of NSAIDs.
There are several strengths to this study. We were able to replicate many of the results reported by Curtin et al. (9). The large sample size in this study made it possible to examine colon and rectal cancer separately; given the potential differences in etiology, it is important for studies to be able to make distinctions between the tumor sites. The case–unaffected sibling control study design also helps avoid false positives that can result from population stratification, and increases the power to detect gene–NSAID interactions (51). There are several weaknesses to this study as well. Associations with rare variants that were below our MAF cut-off (5%) and genetic variants that were not well represented in the relevant database may have been missed. Further, the family based study design may have reduced the power of the main effect analyses (41).
Identifying common genetic variants associated with CRC can help predict risk and contribute to our understanding of mechanisms of colorectal carcinogenesis. Additionally, examining pharmacogenetic interactions between common genetic variants and NSAID use may allow for more targeted recommendations of NSAIDs as chemopreventive agents. Ultimately, our findings, which partially replicated the results of a previous study, suggest that variants in IκBKβ and NFκB1 are probably associated with CRC risk. Genetic variants in IκBKβ appear to alter the risk of colon cancer, whereas variants in NFκB1 appear to result in risk modifications in opposite directions for colon and rectal cancer. The present results also begins to shed light on links between variation in key NFκB-signaling pathway genes and NSAID use, suggesting that the prostaglandin synthesis pathway is not the only pathway that should be considered when investigating NSAID effects on CRC risk. The common variants identified here should be considered for future research, not only in epidemiologic studies of CRC, but also in functional studies of these genes.
Supplementary Tables 1–3 can be found at http://carcin.oxfordjournals.org/
National Cancer Institute (R01CA112516); NIH training grant (T32 CA009001 to E.M.P.).
The contents of this article does not necessarily reflect the views or policies of the National Cancer Institute or any of the collaborating centers in the CCFRs, nor does mention of trade names, commercial products, or organizations imply endorsement by the US Government or the CCFR. CCFR centers providing data for the analysis include: Australasian Colorectal Cancer Family Registry (U01 CA097735); Familial Colorectal Neoplasia Collaborative Group (U01 CA074799); Mayo Clinic Cooperative Family Registry for Colon Cancer Studies (U01 CA074800); Ontario Registry for Studies of Familial Colorectal Cancer (U01 CA074783); Seattle Colorectal Cancer Family Registry (U01 CA074794); University of Hawaii Colorectal Cancer Family Registry (U01 CA074806); and University of California, Irvine Informatics Center (U01 CA078296).
Conflict of Interest Statement: None declared.
PubMed Central Canada is a service of the Canadian Institutes of Health Research (CIHR) working in partnership with the National Research Council's national science library in cooperation with the National Center for Biotechnology Information at the U.S. National Library of Medicine(NCBI/NLM). It includes content provided to the PubMed Central International archive by participating publishers.


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Tanya Marie Hall (Age: 34)
92051 Oceanside CA
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Photo Flash: Broadway at Birdland's Latest Cast Party and the ...
28.06.2012 [Broadway World] - Christine Pedi, star of Newsical, the Musical, sang a hilarious song about missing Oprah Winfrey, twin brothers Will and Anthony Nunziata gave a taste of their upcoming concert at Feinstein's, and jazzer La Tanya Hall dazzled with a swinging tune.
Zumba for Your Health at DeHart - Maplewood, NJ Patch
22.03.2012 Located at 120 Burnett Avenue, DeHart offers a dynamic Saturday morning session at 11 a.m. with instructor Tanya Hall, who revs up her class with fiery Latin, Caribbean, belly dance and hip-hop rhythms along with her own ...
LA TANYA HALL Friday/Saturday December 5-6, 8PM Tickets, Multiple...
Eventbrite - Cafe Noctambulo at Pangea presents LA TANYA HALL Friday/Saturday December 5-6, 8PM - Friday, December 5, 2014 | Saturday, December 6, 2014 at Cafe...
Hattie Marie Hall | TheCabin.net
25.07.2008 Hattie Marie (Turney) Hall, 82, of Greenbrier passed away Tuesday, July 22. Born in Greenbrier on Oct. 16, 1925, she was a daughter to the late John Oliver and Mary Leota (Ford) Turney and the widow of George Edward Hall ...
Management & Stakeholders
Tanya Hall | Greenleaf Book Group LLC | Email, CEO,...
Tanya Hall is the CEO of Greenleaf Book Group LLC. Lead411's profile includes an email address, @greenleafbookgroup.com, linkedin, biography, etc
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Tanya Hall | Elance
i work on behalf of a publisher and distributor to independent authors and small presses. We offer services a la carte when the project is right. Our...
Tanya Hall, Photographer, Montreal, Quebec, Canada, Modelmayhem.com
Official model mayhem page of Tanya Hall; member since Oct 3,2011 has 9 images, 33 friends on Model Mayhem.
Tanya Hall - Previous Managing Member for Absolute Services, LLC
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Tanya Hall | Greenleaf Book Group LLC | ZoomInfo.com
Find business contact information for Tanya Hall, Business Development Manager, Greenleaf Book Group LLC and see work history, affiliations and more.
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About | Tanya Hall
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BookMarketingBuzzBlog: Interview With Tanya Hall, Greenleaf Book...
Interview With Tanya Hall, Greenleaf Book Group CEO. A leading distributor and publisher speaks out! 1. Tanya, as CEO of a mid-sized book ...
Marie Hall
Welcome to the Town of Marlborough, where you will experience the relaxing rural charm of a community with 6094 residents and over 200 local businesses that...
H Actors
Tarzan ~ Additional Voice. The Tigger Movie ~ "Your Heart Will Lead You Home (End Title)" Chorus. La Tanya Hall. The Lion King II: Simba's Pride ~ Additional ...
Isabelle Marie Hall at Northwest Vista College - RateMyProfessors.com
Rating and reviews for Professor Isabelle Marie Hall from Northwest Vista College San Antonio, TX United States.
Tanya Hall-Davis at Clayton State University - RateMyProfessors.com
Rating and reviews for Professor Tanya Hall-Davis from Clayton State University Morrow, GA United States.
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classmates: Tanya Hall
Orange High School, Orange, CA, 1982-1986
classmates: Tanya Hall
Irma Marsh Middle School, Ft. Worth, TX, 1995-1999
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Dillard High School, Ft. Lauderdale, FL, 1994-1998
Tanya Hall: Indiana Business Research Center
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IMDB Filmography: Ann Marie Hall - IMDb
Actress: The People vs. Larry Flynt (1996) · Come Early Morning (2006) · Tennessee Queer (2012) · Streaker (2007).
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Marie Hall, Director: Akha Unspoken
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legacy.com: Tanya Hall
Tanya Marie Hall Elberfeld, IN Tanya Marie Hall, age 58, passed away Thursday, October 30, 2014 at Charlier Hospice in Evansville. She was preceded in death by father, Karl
legacy.com: Mrs. Tanya Hall
View the tribute video here: http://videos.lifetributes.com/536869 Tanya Marie Hall, age 58, passed away Thursday, October 30, 2014 at Charlier Hospice in Evansville. She
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Fayette County - MARIE HALL, 79, died April 27, 2012. Peebles, (901)465-3535
findagrave: Hall, Marie
11/12/1890 - 07/3/1981, Minneapolis (Hennepin County, Minnesota)
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Tanya Marie Hall - Genealogy - Geni
View Tanya Marie Hall's genealogy on Geni helping Tanya Marie Hall and others research their family trees, with over 100 million profiles of ...
Tanya Marie Hall - Genealogy
View Tanya Marie Hall's genealogy family tree on Geni, with over 150 million profiles of ancestors and living relatives.
Tanya Hall
Top record matches for Tanya Hall 1940 United States Federal Census Name : Hall Minnesota Birth Index, 1935-2002 Name : Tanya Marie Hall
Tanya Hall - Records - Ancestry.com
... 1903-1997 Tanya June Hall found in Texas Birth Index, 1903-1997 Hall found in 1940 United States Federal Census Tanya Marie Hall found in ...
Tanya Hall | JustGiving blog
A blog for charities and professionals on digital fundraising. Read inspiring stories, insights, tips and tools on using digital to reach more supporters and...
F. Marie Hall SimLife Center | SmithGroupJJR
SmithGroupJJR is one of the largest architecture, engineering and planning firms in the U.S., ranked #1 for design quality based on design awards won in ...
Books & Literature
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Marie Hall Ets | LibraryThing
Works by Marie Hall Ets: Play with Me, In the Forest, Just Me, Gilberto and the Wind, Nine Days to Christmas: A Story of Mexico, Mister Penny's Circus,...
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Alibris has new & used books by Marie Hall Ets, including hardcovers, softcovers, rare, out-of-print first editions, signed copies, and more.
Nine Days to Christmas: A Story of Mexico by Marie Hall Ets —...
Nine Days to Christmas has 762 ratings and 109 reviews. Kathryn said: 4.5 STARSA charming, sweet story about the posadas (special parties leading up to...
Marie Hall on Yahoo! Music
Stradivarius, 1709 ex Viotti-Marie Hall pictured Marie was the daughter of Edward Felix Handley Hall, a harpis... this is my interpretation of the Walter Trout
Marie Hall on iBooks
Preview and download books by Marie Hall, including Her Mad Hatter, Kingdom Collection: Books 1-3, Hook's Pan, and many more.
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Tanya Hall From Studio City, Los Angeles
Tanya Hall of Studio City is on track to graduate with honors in the medical school's research and experimental program so that she may one day be able to cure…
Find Cash Advance, Debt Consolidation and more at Hotfilefinder.com. Get the best of Insurance or Free Credit Report, browse our section on Cell Phones or...
Tanya Hall
Tanya Read more about homelessness, coordination, methodology, learnings, closely and oversee.
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Marie C Hall
View Marie C Hall's professional profile. Publications: 5 | Citations: 41 Field Rating: 3. Fields of study: Psychiatry & Psychology, Molecular Biology
IJERPH | Free Full-Text | Long-Term Low-Level Arsenic Exposure Is ...
15.03.2011 1 F. Marie Hall Institute for Rural and Community Health, Texas Tech University Health Sciences Center, 3601 4th St., STOP 6323, Lubbock, TX 79430, USA 2 Department of Neurology, Texas Tech University Health Sciences ...
Nettie Hartsock: Understanding the Bestseller lists
09.03.2007 There is a great blog post on how a book gets to best-seller status and a good cautionary tale about making the "best-seller" claim by Tanya Hall of Greenleaf Publishing on the Big Bad Book Blog. Go and read it!
Video & Audio
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Tanya Hall, Business Development Manager - YouTube
Speaking samples of Tanya Hall, Greenleaf Book Group's Business Development Manager, at the Austin Publishing University in August 2009 and the Relationship ...
Arthur Murray Dance Studio Montclair - Zumba Fitness with Tanya Hall...
Dancing is as easy as walking once you are taught by an Arthur Murray expert.
La Tanya Hall singing It's Alright with me - YouTube
La Tanya Hall singing Its Alright With Me by Cole Porter at the legendary Feinsteins at the Regency in support of her album Its About Time, available on Brid...
Zumba Fitness Say Na, Say Na Bollywood Bhangra - Tanya Hall - Arthur...
Zumba Class - Tanya - Arthur Murray Dance Studio Video By Peter Hilaire
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Telehealth saves Medicaid money, helps burn patients
27.07.2012 [Examiner.com] - Thanks to dermatologic consults now being done through telemedicine, Medicaid burn patients in El Paso, TX no longer have to travel six hours to see their doctors, according to Debbie Voyles of the F. Marie Hall Institute for Rural and Community Health
Philadelphia To Hold 6th Annual Global Fusion Festival
21.07.2012 [KYW Newsradio] - The event will feature some well known artists like Grammy nominated vocalist Kenny Lattimore. Organizer Tanya Hall of Philadelphia's Multicultural Affairs Congress says there will be something for everyone. "The event is free, it's for kids as well as
Allegan hospital foundation awards scholarships
19.07.2012 [Allegan County News] - The scholarship fund is made up of the Schuyler Mellen Education Endowment Fund, Marie Hall Nursing Scholarship Fund, Debra Rae Daniels Memorial Fund and a general fund maintained by the foundation. The Allegan General Hospital Foundation
IU Kelley School report: Indiana exports totaled $32.2 billion in 2011 ...
18.07.2012 [Indiana University] - Tanya Hall, an economic research analyst at the IBRC and a co-author of the report, observed that Indiana has outperformed the nation in its exports' annual rate of growth over the past 10 years, 8.1 percent versus 7.1 percent. The global slowdown
Reports & Statements
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Twitter Posts: Luisa (luisaliving)
25.06.2012 @Tanya_Hall_ she is gorgeous!
Twitter Posts: Tanya (Tanya_Hall_)
25.06.2012 My little beagle girl :) #itsella @peta http://t.co/uwgZhRYW
Twitter Posts: Tanya (Tanya_Hall_)
24.06.2012 Ok Grosjean up to 3rd- I'm eating my sarcasm now #f1
Twitter Posts: Tanya (Tanya_Hall_)
24.06.2012 Mark Webber: "Grosjean to win". Yeah nice one Mark. #f1
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Too hot to have fun
19.07.2012 [Winnipeg Sun] - You get the weather channel saying 'humidex warning, stay inside,' so it's kind of a catch-22 situation there," said Tanya Hall, co-owner of Fun Mountain Water Slide Park. Hall believes people might underestimate the relief water provides. "It really
• Jail bookings — July 26, 2012
26.07.2012 [Reporter-Times] - Shelia Marie Hall, 63, Mooresville, operating while intoxicated with a previous conviction and two counts of operating while intoxicated. Shane Logan Kelley, 19, Mooresville, resisting law enforcement and reckless driving (speed). Brandon Thomas King
Jan-Marie Hall | LinkedIn
View Jan-Marie Hall's professional profile on LinkedIn. LinkedIn is the world's largest business network, helping professionals like Jan-Marie Hall discover ...
Sarah Marie Hall - Google Scholar Citations
Follow new citations. Create alert. Cancel. Sarah Marie Hall. Hallsworth Research Fellow, University of Manchester. Ethics, Consumption, Families, Ethnography ...
Tanya Hull - Ballotpedia
Ballotpedia: The Encyclopedia of American Politics
Travel, Food, Words
Travel, Food, Words
Tanya Hall Homes | Royal Lepage
Welcome to Tanya Hall Homes London Ontario. For all your realty needs.
Online Memorial - Marie Hall (1918 - 2008) - Imorial
This online memorial is a tribute to Marie Hall (1918 - 2008). A memorial website is a place for families to come together to remember someone special they have loved ...
Spin Cycle: The Coup, "Sorry to Bother You" | Popblerd!!
06.11.2012 Boots has been vulnerable and tender before — think back to "Underdogs" from Steal This Album, or Pick A Bigger Weapon's "Tanya Hall", or even Party Music's pastoral "Heven Tonite" — but that he's willing to do so on such ...
RhiReading: Review: Her Mad Hatter by Marie Hall
30.10.2012 Her Mad Hatter (Kingdom Series #1) by Marie Hall Paranormal Romance, Fairytale Retelling Ebook 99¢ (129 pages, SELFPUBLISHED) Alice is all grown up. Running the Mad Hatter's Cupcakery and Tea Shoppe is a ...
Things to do at Home when Sick and Injured and Bored | Tanya Hall
27.03.2010 You may well have thought that every top ten list had already been done on the internet, but here comes yet another previously unfathomable one- the top 10 things to do when you're incapacitated. I recently had a toe injury, ...
James Joyce Abridged | Tanya Hall
30.12.2011 I won't take the standard 20896443 words to go into why James Joyce's Ulysses is such a spectacular book, but I will give you the top 300 words used in his novel's entirety. If you zoom your eyes over them all as quickly as ...
The Witching Hour by Marie Hall | The Indie Bookshelf
19.09.2012 The Witching Hour by Marie Hall Review by Ian Seta - Guest Reader. What would happen if the grim reaper fell in love with the woman whose soul he was sent. to harvest? "He should say goodbye, walk away and never ...
Woman charged with kidnapping and raping 2 boys » The ...
02.05.2012 Kristen Marie Hall. Suspect shoots 2 officers; 1 dead, 2 injured. By Monica Land JACKSON – Anyone traveling in the west Jackson area Tuesday afternoon knew something was wrong. Patrolmen raced down the streets ...
On Chucking It All and Going On the Road « Douglas Simonson: An ...
08.06.2011 You can't help but win in this adventure; you'll find new inspiration and perspective that only travel can bring, and your work and life will be the better for it. Reply. Tanya Hall says: June 30, 2011 at 12:22 am. So well put …
GHG Marie Hall
biography of marie pauline hall famous violinist
La Tanya Hall | SoulTracks - Soul Music Biographies, News and Reviews
Official Biography (courtesy of Tom Estey Publicity) If one word could be used to describe La Tanya Hall's talent, it would have to be diverse.
La Tanya Hall: Bluesette – Jazz.com | Jazz Music – Jazz Artists...
Has Toots Thielemans heard this version of his classic tune? If not, someone please FedEx it to his immediate attention. This song cannot be performed any...
Marie R. Hall - Artist, Fine Art Prices, Auction Records for Marie R....
Marie Hall: AskART art price guide for Marie Hall and 200,000+ international and American artists - Marie R. Hall fine art prices, auction results, auction images
Tanya Hall Archives - Black Enterprise
3 Tips for Organizing a Major Event. In five years Tanya Hall grew the Global Fusion Festival into one of Philly's biggest events and she's ready to share her knowledge
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The Padres admit this looks like a good time to promote first baseman Anthony Rizzo from the minors.
San Diego is opening a six-game road trip. With right fielder Will Venable optioned to Class AAA Tucson, the Padres could move now hot-hitting first baseman Brad Hawpe to his natural position of right field. Rizzo would help shore up the Padres' defense, and with Hawpe and Ryan Ludwick hitting, little offensive pressure would fall on Rizzo.
Rizzo, 21, is hitting .366 with a .446 on-base percentage, a .717 slugging percentage, 14 homers and 56 RBI through 43 games for Tucson. He ranks eighth in the Pacific Coast League in batting, second in homers and first in RBI.
But Padres general manager Jed Hoyer says the time is still not right. For one, Rizzo has a bruised hand and thumb on his left hand.
"There is still some development (to be done)," Hoyer said. "When he gets here, he is not going to go back down. And we're not going to bring him up as the remedy for the offense. The timing and situation has to be right."
Rizzo was acquired by the Padres in the December deal that sent first baseman Adrian Gonzalez to the Red Sox.
Copyright (C) 2011 The Sports Xchange. All Rights Reserved.


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Take corners the horror! With the 'Standard' corner protectors defuse window cornices, furniture, table plates & co.!
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People have trusted Belle Tire for the best value since 1922. Now were working even harder to bring you the best tire price,period! And get you Out-The-Door with More more value,services and protection the other stores can't offer at any price!
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People have trusted Belle Tire for the best value since 1922. Now were working even harder to bring you the best tire price,period! And get you Out-The-Door with More more value,services and protection the other stores can't offer at any price!
Lowest Tire Price, Period!
Belle Tire in Portage, Michigan has provided high quality tire service since 1922. Visit Belle Tire for complete tire and wheel service and repair, rotation, auto tune-ups, brake service, oil and lube, general car repair and even windshield and auto-glass service.
Belle Tire is located at the address 6283 S Westnedge Ave in Portage, Michigan 49002. They can be contacted via phone at (269) 323-4600 for pricing, hours and directions. Belle Tire specializes in Performance Cars, Domestic, Motorcycles.
Belle Tire has an annual sales volume of 2M – 4,999,999. .For more information contact Kevin Borr, Manager
Belle Tire provides Replacements, Auto Repairs,...
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Next time I need tires, I'll definitely go to Belle Tire Portage. The guys are great! Fixed a small leak in my tire, caused by a tiny piece of metal at no charge. Now that's customer service!
Update to my review: they ordered new hub caps and refused to put them on for me. Manager was rude and told me they do not want to do business with us anymore. They will be turned into the better business bureau and regional manager will be notified! Review below also stands: Buyer beware!!! I bought …
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The Department is composed of the PCT Legal Division, the PCT International Cooperation Division and the PCT Business Development Division.
The Department is responsible for the development of policies and the provision of strategic direction to preserve and strengthen the role of the PCT as the central node in the international patent system, and for the support of PCT system stakeholders, including Member States (and their IP-Offices in their capacities as PCT receiving Offices, International Searching and Preliminary Examining Authorities, and designated and elected Offices), the user community, and intergovernmental and non-governmental organizations.
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