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text:
December 07, 2015
Future vehicles equipped with vehicle-to-vehicle and vehicle-to-infrastructure technology – commonly referred to as V2X – will also be able to exchange position data with pedestrians and bicyclists who carry a smartphone or special transponder, according to auto safety supplier Continental Corp.
As a result, connected vehicle technology now under development will eventually help prevent collisions involving the most vulnerable road users, the company said.
Modern smartphones are already capable of WLAN communication. With a few changes to the communication chip, smartphones can be adapted to exchange V2X messages with vehicles, Continental said.
"Protecting vulnerable road users such as pedestrians and cyclists is one of the greatest challenges on the road to accident-free driving," explained Dr. Bernhard Klumpp, head of Continental's passive safety and sensorics business unit. "Short-range communication can play a decisive role here, too, and brings us one step closer to our goal of zero traffic fatalities."
The position and movement predictions of pedestrians and cyclists will be transmitted anonymously to vehicles using V2X messages. Incoming messages will be authenticated and processed within less than 0.1 second. The higher-level control unit in the vehicle will decide whether the driver needs to be warned or if an intervention in the vehicle dynamics is necessary, Continental said.
Determine the actual cost of owning and running a vehicle in your fleet. Compare vehicles by class and model.
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Henry Paetzel was the manager of automotive services at General Mills until he retired from the company in 2007.
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Henry Paetzel was the manager of automotive services at General Mills until he retired from the company in 2007.
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Few celebrities in Hollywood who claimed to have remained down to Earth are able to convince us that they've actually done so. Most of the time, when someone gives an interview and goes on and on about how "real" they are or how "normal" they are, it's hard to take them seriously. However, Amy Schumer is the exception. Maybe I'm naive, but when Amy talks, I believe.
The comedian recently sat down with Howard Stern for a candid interview and the pair got on the topic of networking in Hollywood.
"That is my worst nightmare… That's disgusting. It's just so fake. It's people doing an impression of having a conversation."
Oh, juicy.
Jennifer Lawrence's BFF continued, adding that she's "not trying to make lots of celebrity friends."
Howard brought up the Met Gala and asked Amy how she felt about attending. Amy responded:
"I left not the second I could, I left earlier than I should have been allowed… I got to meet Beyoncé and she was like 'Is this is your first Met Gala?' and I was like 'It's my last.'"
To hear more about Amy's no holds barred opinions on socializing in Hollywood, listen below:


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56 years/ 5Ft. 10In. (177.5 cm)
Bachelor Degree
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Lives in South Africa
Hindu, Nair
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About MI-417838
I Place High Priority in My Prayer Religion and Spirituality. My Characteristics Need and Personality Places High Priority in Me to Demonstrate and Show Respect Honor Dignity Trust and Loyalty to Firstly My Soulmate and Secondly to People. It is My Duty and Responsibility to Always Give Inner Soul Love Affection and Care to My Soulmate and also to Do and Give Her Pleasant Surprises Just to Ensure She Enjoys the Greatest Moments of Happiness. br br it Remains My Duty and Responsibility to Create and Support a Home for My Soulmate that is Always Enriched By Happiness Peace and Joy. My Soulmate Must Live Her Life with all Safety Certainty Security and Stability. in My Home - I Would Cook Very Good Food for Her and Would Play a Pivotal Role in Support of Her Life. br br i am Currently Employed in the Government and Public Service as a Municipal Finance and Institutional Governance Advisor. I Enjoy the Weekend Privileges and Opportunities to Play Golf and Attend the Virgin Active Gym in Johannesburg South Africa. I Enjoy My Annual Holidays in a Foreign Country in the East and in the West. I Enjoy Doing Humanitarian Duties to the Poor Children and to Old People. I Enjoy Indian and English Music and Going to the Movies. br br it is My Expectations that My Soulmate Would Always Stand By Me and Support Me Towards Creating a Home that is Enriched By Happiness Peace and Joy. I Would Always Make Her Enjoy Good Laughter. br br i am Currently Living Alone in My Rented Apartment and in Good Health and Enjoying Growing Prosperity. br br thank You
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The 2005 Audi S4 comes equipped with a 4.2 liter, V-8 cylinder engine matched with a 6 speed manual transmission. The vehicle also comes equipped with aftermarket chrome rims. This is a four door sedan with an exterior color of brilliant red.
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Chris Haynes, Simon Miles, Michael Luck. Probationary Contracts: Reducing Risk in Norm-Based Systems. In Michael Rovatsos, George A. Vouros, Vicente Julián, editors, Multi-Agent Systems and Agreement Technologies - 13th European Conference, EUMAS 2015, and Third International Conference, AT 2015, Athens, Greece, December 17-18, 2015, Revised Selected Papers. Volume 9571 of Lecture Notes in Computer Science, pages 3-18, Springer, 2015. [doi]
Abstract is missing.


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Who is She?
She is a wanderer, she is a student of life, she's an independent woman, she's a professional, she works a 9-5 job, she's an ordinary girl who craves adventure, and she is a person who finds time to live, love and travel.
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Adam Jeffery Collinsworth
- 33 years old
- Date of birth: Mar 14, 1966
- Date of passing: Dec 13, 1999
|Let the memory of Adam be with us forever
This memorial website was created in memory of our loved one, Adam Collinsworth, 33, born on March 14, 1966 and passed away on December 13, 1999. We will remember him forever.
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Looks like Her Story 2 is a real thing that's going to happen at some point. Neat. I loved the murder mystery at the heart of the first FMV game.
Looks like Her Story 2 is a real thing that's going to happen at some point. Neat. I loved the murder mystery at the heart of the first FMV game.
Mirror's Edge 2 Is Now Mirror's Edge: Catalyst
For the longest time, Mirror's Edge 2 has seemed like one of those sequels that needed to happen but probably never would. Put your anxious mind at ease. The thing has a real name now! And it's definitely "not a sequel."
A Look At What Alan Wake 2 Could've Been
Fans of the original Alan Wake have long wondered why their hunger for creeptacular suspense-filled third-person action game goodness hasn't been fed with a sequel. This week, they got more of a proper answer. And a new hope.
One Thing That'll Be Different In Dead Island 2? Freeze Rays.
You know how they say that there's more than one way to skin a cat? Well, there's more than one way to kill a zombie, too. In case you thought you'd run out of new ways to lay the living dead to rest, Dead Island 2 is here with a new gameplay trailer to try and convince you it's still not out of ideas.
What's That? Modern-Day Gaming Has Too Many Sequels? Actually...
Whenever you see someone gripe about how uncreative the game industry is, the 'observation' almost always seems to carry a hint of nostalgia to it. It's almost as if people want to suggest ~the good 'ol days~ were so much better.
Well, Thank God, Someone's Finally Making the Sequel to Chess
Next time you complain about Half-Life 3 taking forever, consider this: the modern game of chess is believed to have originated in 1575, and only now is Chess 2: The Sequel coming out. And it's an Ouya exclusive.
Please Stop Complaining About Sequels That Change Things Up
What's the better game, a sequel that merely enhances ideas established in previous games, or one that goes in a completely new direction? Commenter DanimalCart is tired of people complaining about sequels that aren't just more of the same.
Gamers Are Excited About Sequels, Says Weird Poll
The research group Nielsen has released a poll under the headline "Video Gamers Eager for New Titles from Familiar Franchises this Year." They combined "eight key consumer metrics, including awareness and purchase interest" into one score for each game, ranked out of 100.
Do You Crave Sequels or Something Entirely New?
Commenter Monsieur Froid returns to Speak Up on Kotaku once more to ask readers whether they want daring new intellectual property or games that build upon the tried and true.
Let's Play The Dream Video Game Sequel List Game
It's Monday morning, and Speak-Up on Kotaku is feeling a little playful, so we're going to play commenter Wocalax's little dream video game sequel game.
The Next Ghostbusters Game Is A Throwback
Last year's Ghostbusters: The Video Game was practically Ghostbusters 3, a reunion of the main cast from the 1980s movies in virtual form. The next one is more like a Gauntlet or Robotron sequel.
Homefront's Future Plans Include London
At E3, Homefront was offhandedly mentioned to me as inspired by Resistance, just without the aliens, naturally. As if to drive that point home, the man in charge of THQ's core games portfolio already has designs on London.
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Bungie's writers considered extending the saga of Master Chief beyond Halo 3 - whose ending certainly left an opening for it - before settling on the prequel story of the Fall of Reach, the studio's community manager said.
Alpha Centauri & Railroad Tycoon Sequels Are On Sid's List
During our chat with Sid Meier earlier this week, fans couldn't help asking about classic games like Alpha Centauri and Railroad Tycoon. They want sequels.
Website Registrations Tease GoldenEye, Driver Sequel
It doesn't mean such games are in development - at most the companies owning these marks have moved to protect them - but new domains for GoldenEye and Driver have been registered by Activision and Ubisoft.
Plants Vs Zombies 2 Guaranteed To Ship In Next Decade, Not In 2010
Just got done with an entertaining meeting with some of the top people behind Plants Vs. Zombies, Bejeweled, Peggle and Zuma. They don't talk much about future plans, but made Kotaku readers one guarantee.
THQ Returns To Saints Row, Darksiders, And De Blob Next Year
THQ is rolling out the sequels in fiscal year 2012, with releases planned for Saints Row 3, a Darksiders sequel, and a follow-up to the Wii-exclusive hit de Blob.
News of a New Street Fighter Coming from Capcom?
After a certain number, a sequel is foregone conclusion. Rocky IV assured Rocky V. Jim Bob and Michelle Duggar's 18th baby guaranteed a 19th. So an announcement of an announcement about a possible Street Fighter sequel is not stop-the-presses news.
Activision: Sequels Offer "Road Map For Innovation"
Pity the video game sequel, perpetually scapegoated as an evil of the industry. To the rescue of its reputation this week came Activision Blizzard boss Bobby Kotick. The exec recently explained what sequels are good for, besides profit.
Kotick: Most Gamers Prefer Sequels to New IP
Those CEOs, the things they say when they're talking to the magazines CEOs read, thinking no one's watching. Talking to the Economist, Activision's Bobby Kotick said "a small segment" of gamers are the ones insisting "everything has to be new."


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A Denver company denied licenses to open medical marijuana operations in Worcester and other Massachusetts communities hit another roadblock Thursday when a judge denied Good Chemistry of Massachusetts Inc.'s request for a preliminary injunction against state public health officials.
Suffolk Superior Court Judge Thomas B. Billings wrote that Good Chemistry's applications contained errors and ambiguities that public health officials were entitled to consider when judging applications.
"The applicants, the affected, and the citizenry as a whole all have an interest in seeing that (registered marijuana dispensaries) are awarded according to a process that is fair, orderly, compliant with statutory and regulatory standards, and based on applications that are clear, truthful and accurate," Mr. Billings wrote.
Good Chemistry, which originally sought licenses to operate in Worcester, Boston and Salem but then indicated it would only seek a Boston license if the injunction were approved, said it was examining all options and continuing to work with state officials.
"We are surprised by the decision and genuinely befuddled by the entire application process," the company said in a statement.
"It appears," Good Chemistry continued, "that the judge was persuaded that although the alleged offending language was not a misrepresentation, it is still difficult to restrain a state agency."
The state's Department of Public Health said it was "pleased that the court's decision has again validated our comprehensive and thorough process to ensure patient access and public safety across the Commonwealth."
The ruling represented the latest twist in the state's contentious process to evaluate and award licenses to groups seeking to launch the first Massachusetts medical marijuana dispensaries.
State voters approved legalization of medical cannabis in 2012. Dispensary applications soon flowed in, but some had problems. Only 11 dispensary licenses were awarded statewide, and no licenses were awarded for Worcester and Boston.
Good Chemistry, which sells medical marijuana in Denver, was initially granted provisional licenses in Worcester and Boston, plus an opportunity to seek a license in a county where no dispensaries were sited. But state public health officials later reversed course and gave no full licenses to Good Chemistry, saying the company submitting misleading, incorrect, false or fraudulent information.
In its applications, Good Chemistry indicated it had contacted and met with the sheriff and police chief in Worcester, but it had not. In addition, the company's application for a Boston license described outreach to a majority of state legislators from Boston and the city councilor representing the neighborhood of the proposed dispensary, but that never took place.
Good Chemistry argued its wording about meetings with officials in Worcester did not mean what the state read in it, and it said it inadvertently put wording about Worcester in its Boston application.
Contact Lisa Eckelbecker at firstname.lastname@example.com. Follow her on Twitter @LisaEckelbecker.


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wrestling / News
WWE News: Miz TV Returning, Elimination Chamber Update, Tag Team Breaks Up
– It was announced on Smackdown Friday night that Miz TV will return to Raw next week, with Paul Heyman as his guest.
– Contrary to reports, the Smackdown Elimination Chamber match participants were not announced on Smackdown. It had originally been reported that Daniel Bryan, Kane, Randy Orton, Great Khali and Jack Swagger would all be involved.
– The Rhodes Scholars broke up on Smackdown. The two partners said they would be focusing on their singles work, "but remain friends."
Must-read news from around the site:
* Adrianne Curry tweets her awesome cleavage from bed
* Check out the latest single from Drake
* Beyonce's world tour to include Jay-Z?
* Check out a new image from Riddick
* Revenge star cast as female lead in Captain America: The Winter Soldier
* 411's MMA Roundtable Preview – UFC 156: Aldo vs. Edgar
* The Top 10 Replacement Superheroes (#10 – 6)


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How to spoil a car?
your neighbor constantly parked in the wrong place, at the playground, or listening to music really loud at night, and your requests to nothing lead?In such a situation you thought about the damage of his car.
There are a lot of options as to spoil the car.The article presents some of them.
- You can pour glue door locks.The owner of the car will be a long time to find out, why not insert the key into the keyhole.
- You can also paste the wipers.In this case, the owner of the damaged car will ride with dirty glasses.
- The current method is sticking a piece of paper with the inscription on the windshield of the driver.After 15 minutes, it can not be removed.
- You can break an egg (preferably rotten) on the surface of the machine and the host will be a long time to enjoy the aroma of spoiled eggs.
- If you have access to the interior of the machine, you can use fresh eggs.To do this, drag the contents of a medical syringe, and then send the liquid under the car upholstery.A few days later the egg stuhnet and will either have to sell the car, or completely change the upholstery.This way you can seriously damage the enemy vehicle.
If you leave the evening with wheat or other cereals on the hood of the car, you will enjoy the morning scratched hood, as night birds will gather all the grain and at the same time scratch claws and beaks hood.
Vaseline and gouache
can spread doorknobs with Vaseline or black gouache.After the owner of the car will take up the handle of the machine, it is a long time will not be able to wash the black gouache or petroleum jelly to hands.
If you want to seriously damage the machine enemy, it is necessary to pour a cup of sugar in the gas tank.In this case the machine be acquired, it will travel a little bit and stop, as clogged filter.A car owner will have to send the machine in the service and clean the fuel tank, filters and pumps.
order to ruin the lives of several cars and motorists, you can change them on one number.If they are stopped by traffic police, it would be difficult to explain why the numbers are different, and most likely they would be referred to shtrafploschadku to clarify all details.
If your abuser car dark color, you can sprinkle it with potassium permanganate.The owner just did not notice, but when it starts to rain, potassium permanganate gets wet.It will corrode the varnish, and the car starts to rust.
If you score the exhaust pipe potato, the machine will not start up until the vegetables will not be removed.
Polyurethane foam
exhaust pipe must be filled with foam, but only so that it was not visible from the outside.After the driver will lead the car, the smoke will go on all sides.
Now that you know what you can spoil the enemy machine, but do not overdo it, because some methods may cause injury to a person.


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Scrabble?! NONEARNING
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Anagrammer is a game resource site that has been extremely popular with players of popular games like Scrabble, Lexulous, WordFeud, Letterpress, Ruzzle, Hangman and so forth. We maintain regularly updated dictionaries of almost every game out there. To be successful in these board games you must learn as many valid words as possible, but in order to take your game to the next level you also need to improve your anagramming skills, spelling, counting and probability analysis. Make sure to bookmark every unscrambler we provide on this site. Explore deeper into our site and you will find many educational tools, flash cards and so much more that will make you a much better player. This page covers all aspects of NONEARNING, do not miss the additional links under "More about: NONEARNING"


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Creative cards for happier holidays. Buy 8, save 20%. Buy 16, save 30%.
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text: I am a Massage Therapist, i own and operate my own business in Rochester, MN called Kraft Therapeutic Massage. I found It Works because i was looking for something to help me get clean nutrients into my body so that i can function at 100% for every client! Also, i wanted a well-rounded, ethical product to stand behind to offer my clients what is best for their health. Whether you need wellness products or to supplement your income; Let me help you live life to its fullest. Let's Talk.


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IRC to be replaced with Google Plus.
Instead of IRC that is old way to chatting with people should be replaced with Google Plus that is easy to use by country/Language.
Voting on Ideas
Vote for your favorite ideas by clicking on the up arrow.To undo an upvote, simply click the arrow again. This second click removes your vote.
-15 votes
Idea No. 128


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Researchers: Marija Ilic, Ozan Tonguz
Research Area: Next Generation Secure and Available Networks
Making the Support Vector Machine (SVM)- Based Relays Secure
Today's electric power systems are very large and complex interconnected networks. The key role of electric power systems in modern society imposes stringent requirements for an acceptable level of reliable and secure operation, even under unusual circumstances and adverse conditions such as blackouts. While such conditions may occur with very low probability they may have high impact; hence, the system must be sufficiently adaptive to minimize the adverse effects on equipment safety and the continuity of electricity service. To keep the continuity and the stability of the power system, various procedures are put in place to adjust the system when hard-to-predict large equipment failures occur and to disconnect the service only where it is essential to do so to provide service to the rest of the customers. These procedures are currently a combination of system operator's actions, automated control, and automated system protection.
This project concerns, in particular, the problem of protection for transmission lines. The primary role of a relay dedicated to a piece of equipment is to disconnect this equipment in order to prevent it from getting damaged when the electrical conditions (e.g., the current going through that element) are unacceptable. The protection has by and large, except for some special protection schemes (SPS), fixed thresholds of variables to which it responds when disconnecting equipment. While different traditional relays respond to different physical variables, they all share a common characteristic that their thresholds are set under fixed conditions, and are not adjusted as the system operating conditions vary. They are, instead, deployed and left alone. Consequently, currently implemented relays are not sophisticated enough to protect equipment against serious failures such as blackouts. In some situations they are not adaptive enough to discriminate between the fault and non-fault (normal) conditions, or to react correctly to faults. This malfunctioning of relays has been inherently associated with all major system blackouts, and has been known to have contributed to the accelerated cascading of the initial equipment failure (outage). It is widely recognized by the industry that more intelligent relays are needed which would be capable of reducing the damage to the power systems hardware and, at the same time, localizing the effects of outages without causing cascading equipment failures.
In our group at Carnegie Mellon University (CMU) we are pursuing work toward a new generation of protective relaying. In this project, we improve the protection relays via applying support vector machine classification. Support Vector Machine Classification Based (SVMCB) smarter relays determine their decision boundary based on more than one feature. SVM classification helps to improve the performance of the smarter relays when dealing with complex fault conditions in large scale systems. In our experiments, to improve the accuracy of smarter relays on complex conditions, more than one feature is taken into consideration at one time. Besides the magnitude of current, which was selected to be the representative feature on conventional relays, phase of current, magnitude of voltage, phase of voltage, real power and reactive power are all candidates in SVM based smarter relays.
Experiments, which are done on IEEE 118 bus systems, conducted at CM show that a high accuracy can be achieved when SVMCB smarter relays are making the decision to discriminate the zone 1 faults, zone 3 faults and normal conditions. Besides these, simulation results indicate that the real and reactive power are two major features in most of the cases. These two features are neglected in conventional relays, which is one of the reasons why conventional relay may malfunction in some critical conditions. The application of these two features in SVM based-relays helps increase the accuracy in critical decision making. Moreover, simulation results also indicate that the SVMCB smarter relays can achieve high accuracy even in the "N-1 condition", which is a more critical condition during systems control process. Besides decision-making accuracy, scalability has also been demonstrated by simulation.


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Scholarship Appreciation Breakfast
Every year, Good Counsel invites scholarship donors to share a lovely breakfast with the recipients of their scholarships. The Scholarship Appreciation Breakfast is a wonderful way for our students to thank the donors who help make their Good Counsel education possible.
At the 2016 Scholarship Appreciation Breakfast, Emily Hall '17 spoke on behalf of the students, thanking the donors for their generosity and ensuring them that their donations are having a significant impact. Alumnus Bradlee Bolino '71 gave the Keynote Address. He encouraged every student at the breakfast to become not only life-long learners, but life-long philanthropists as well. Detailing the ways that Good Counsel gives to each and every student, Brad encouraged the scholarship recipients to cherish these gifts and to one day give back to the community themselves.
Thank you to all of our Scholarship Donors
Dr. Edward '62 and Mrs. Branagan
Ms. Elizabeth Matan
Ms. Molly Nagel
Ms. Meagan Fitzgerald
Mr. John and Mrs. Kathy Poletto
Mr. Michael McGivern '68
Mr. Earl '99 and Mrs. Hunt
Mr. Tim McKenna '88
Mr. Josh '99 and Mrs. Ott
Mr. William Brewer '65
The Aragon Family
Mr. Richard '66 and Mrs. Roderick
Mr. SteveGhent
Mr. Ken Bartee
Mrs. Kathy Dominguez
Mr. Tim Welsh '84
Mr. Robert and Mrs. Sharon Bohlander
Mr. Bruce and Dr. Eileen Haase
JMJ Trust
Carozza Foundation
Mr. and Mrs. Joseph Cardaci, Sr.
Dr. Michael '68 and Mrs. Murphy
Mr. Ed Sciullo '62
Mr. Richard Urban '62
Mr. Joe Howard '67
Mr. Dan Boyle '67
Mr. and Mrs. John Vassos
Dr. Scholl Foundation
Class of 1962
GHR Foundation


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Planet Hulk Trailer (2010)
"Will he save their world... or destroy it?" 02 February 2010 Animated, Action, Sci-Fi 81 mins
When the Hulk becomes too dangerous for the Earth, the Illuminati trick Hulk into a shuttle and launch him into space to a planet where the Hulk can live in peace. Unfortunately, the Hulk's struggle to escape makes a malfunction in the shuttle causing Hulk to land on the planet Sakaar where he is sold into slavery and trained as a gladiator.
Watch the official Planet Hulk 2010 trailer in HD below or find more Planet Hulk videos on Vidimovie.


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|Publication number
|Publication type
|Application number
|Publication date
|Mar 21, 1989
|Filing date
|Feb 29, 1988
|Priority date
|May 7, 1986
|Fee status
|Publication number
|Vincent L. Vaillancourt
|Original Assignee
|Vaillancourt Vincent L
|Export Citation
|BiBTeX, EndNote, RefMan
|Patent Citations (12), Referenced by (89), Classifications (15), Legal Events (7)
|External Links: USPTO, USPTO Assignment, Espacenet
This is a continuation of application Ser. No. 860,581, filed May 7, 1986, now abandoned.
With reference to the field of art as established in and by the United States Patent Office, this invention is believed to be found in the general class entitled "Surgery" and, more particularly, relates to an improvement in a disposable infusion delivery system that provides a constant delivery rate to a patient.
Many infusion systems have been proposed and sold for the dispensing of drugs into a patient. With few exceptions, these systems contain both reusable (hardware components) and disposable parts. These systems include, for the most part, electrical components, with their attendant costs and limitations. The system as shown and described in the present application has an infusion delivery system that does not use or utilize electrical or electronically-related components, and this new and novel delivery system is completely disposable after a one-time use.
The delivery of medication may include a catheter as the vascular access device or dispensing may be through a needle penetrating an implanted vascular access port which in turn is connected to a blood vessel using an internal catheter. The delivery of this medication includes a small receiving means and the delivery is through a catheter-vascular access port at a constant rate for an extended and determined period of time. Devices of this type are preferably light in weight and pocket accessible. The devices are normally disposed at completion of the infused dosage of medication for convenience, elimination of mixed drugs, and minimizing contamination. At present, most, if not all, disposable ambulatory medicator infusion devices employ an elastomeric bladder which is caused to be expanded as the drug is fed or otherwise flows into the bladder. The delivery is dependent upon the capability of the bladder to expand and contract. Among the issued U.S. patents showing or employing bladders as a means of storage and contraction to provide expulsion while providing pressure is No. 3,486,539 to JACUZZI, as issued Dec. 30, 1968. This dispensing device anticipates filling a bladder through a front-connected needle with a flow metering restrictor. U.S. Pat. No. 3,993,069 to BUCKLES et al, as issued Nov. 23, 1976, shows an expansible elastomeric bladder. This patent also has a separate flow-control device and the assembly includes this outer flow restrictor. U.S. Pat No. 4,318,400 to PEERY et al, as issued Mar. 9, 1981, also has an elastomeric bladder-powered infuser and a tubular case enclosure to prevent excessive expansion of the bladder. Drugs are fed through a needle and syringe to the bladder through a resilient plug at the rear of the device. U.S. Pat. No. 4,386,929 was also issued to PEERY et al on June 7, 1973, and is very similar to and is a continuation of U.S. Pat. No. 4,318,400 noted above. U.S. Pat. No. 4,419,096 to LEEPER et al, as issued on Dec. 6, 1983, showed apparatus very much like those to PEERY, noted above, but with an added lumen and bulbar filler portions to establish the contracted shape of the elastomeric bladder when the contents are, or substantially are, expelled.
Briefly, the invention provides an ambulatory infusion device or pump which includes a housing for a fluid, a piston which is slidably mounted in the housing and an elastomer member connected to and between the piston and the housing to stretch in response to movement of the piston during filling of the housing with a fluid and to impose a force on the piston after filling for expelling the fluid through an outlet aperture.
The infusion device is and it does provide, a small, lightweight cylindrical apparatus which is filled with fluid through a delivery device such as a hypodermic needle attached to a syringe and/or a pressurized container. The inflow of fluid causes a slideable piston to move rearwardly in a tubular barrel and elongate an elastomeric member. In this manner, energy is stored which is subsequently used to deliver this same fluid to an attached connector device to a patient's previously inserted catheter. This fluid is delivered at a predetermined rate of flow governed by the force provided by the stretched resilient member. This rate is thus predictable with a determined restrictor size.
The infusion device is sized to be carried inconspicuously on the patient's body. This low-cost infusion device allows it to be used as a disposable product so contamination, cleaning and resterilization problems are not present. The flow of stored fluid is self-regulated without constant monitoring. The fluid can be observed to determine volume remaining or released, clarity of drug (contamination not present).
One embodiment, a sliding piston is carried in a tubular chamber of a housing of selected length. The rear of this tubular housing may be closed by a cap to prevent contamination during filling and, when used, having a small aperture or air vent to prevent the development of negative pressure. The forward end of this housing is conected to a tubing set which includes means for injecting (infusing) drugs/fluids into a delivery system leading to the patient. An ingress means, such as a resilient plug, is provided for the insertion of the fluid (drug) into the tubing chamber, and with the fluid inflow the slideable piston is moved toward the rear of the chamber. This piston is connected at its forward end to an elastomeric strand member, preferably a rubber tube, which provides the compression force (rubber tube in tension) to draw the piston toward and to the front end of the chamber.
The product of the present invention is easily made and assembled. The interface between the elastomeric component and drug is minimal when compared to above-known bladder-type devices, thereby reducing the potential for extractables. The interior chamber between the piston and an end wall of the housing, unlike bladder products, can and does go toward a zero volume since the elastomeric member is preloaded (tensioned). The barrel in which the drug is carried is a see-through product in which medications may be, and usually are, observed prior to and during infusion. This visual potential allows the user to detect contamination, color changes, etc. The leading edge of the piston may be used as a measuring means (similar to present use in disposable syringes) to measure accurately the quantity of medication infused.
This delivery tubing conventionally has a connector by which a disconnect is achieved with a minimum effort, permitting replacement of the device after a one-time use. This discharge tubing from the device usually includes a luer lock hub connector which may include a filter and flow-control restrictor. In use, the fluid to be injected is flowed into the chamber through a one-way valve and/or injection port. The inflow of fluid under pressure into the chamber causes the piston to move rearwardly as this fluid fills the chamber. The rubber tube that supplies the compressing force is stretched (placed under tension) until the chamber is filled with the desired amount. The injection port is then closed. The device is primed by cracking the outlet female luer adapter, with the storage unit height being lower than the outlet. This device is not connected to the patient for a constant infusion delivery.
The infusion device is made for a patient to wear inconspicuously (usually under clothing) and is silent in use and, except for a connection to the catheter in the patient, is entirely self-contained. The intravenous feeding is at a controlled rate, with no adjustment required, and permits this device to be used in and with outpatient care. The administration of fluid through this infusion device is continuous and rate-controlled, so a steady flow is provided to the patient. The delivery rate of infusion fluid is dependent upon the force developed by the stretched elastomeric member which is in tension in combination with the restrictor size. These two parameters determine the fluid delivery rate.
It is anticipated that the device or system will hold about two to sixty cc.s of drug concentrate or mix, and as a fluid be dispensed through the connected tubing to a catheter/vascular access means in the patient. This delivery is at a constant rate for a period of time. As this device is very lightweight and small, the patient is not restricted but may be ambulatory. As this tubular housing is anticipated to be made of substantially transparent materials, the patient may visually ascertain when the fluid has been delivered, how much has been delivered as an infused dosage, and, when desired or empty, disconnected and discarded. A new device may then be connected to again provide a desired constant flow infusion.
This system or device is particularly useful for fluids used in chemotherapy, diabetes, pain relief and other drugs which exhibit a therapeutic effect through constant rate infusion. This system also may be used as a replacement of syringe pumps for home therapy wherein the need for such pumps is indicated. This system or device obviates the need for training and manipulating such pumps. The device, as to be hereinafter shown and described, provides a system that essentially is pre-assembled. requires minimal training, no technical skills, and is self-regulating. The system is tamper-proof in that once a satisfactory hook-up is made, there is no means for the patient to violate the system without the violation's becoming known.
In addition to the above summary, the following disclosure is detailed to insure adequacy and aid in understanding of the invention. This disclosure, however, is not intended to cover each new inventive concept no matter how it may later be disguised by variations in form or additions of further improvements. For this reason, there have been chosen specific embodiments of an ambulatory disposable infusion delivery system as adopted for use in the controlled delivery of medication and showing a preferred means for constructing the device and its use. These specific embodiments have been chosen for the purposes of illustration and description as shown in the accompanying drawings wherein:
FIG. 1 represents a side view, partly in section and partly diagrammatic, and showing one embodiment of a disposable infusion delivery system and showing a flexible tubular means for deliverying fluid to a catheter;
FIG. 2 represents an enlarged sectional side view of a forward extent of resilient tubing and a plug retainer for one end of this tubing;
FIG. 3 represents an enlarged sectional side view showing this same tubing with its other end secured in and to a slideable piston;
FIG. 4 represents an enlarged, very fragmentary, sectional side view showing a resilient plug mounted in a port formed in the extending portion of the housing nose portion and providing puncturing means for a hypodermic needle;
FIG. 5 represents an enlarged, and partly diagrammatic, sectional side view of luer lock connecting members;
FIGS. 6 A, 6 B and 6 C represent sectional side views of an alternate cylindrical container, the slideable piston illustrted in three positions;
FIG. 7 represents an enlarged, and diagrammatic, expanded view of the slideable piston and a means of securing the end of a resilient tubing to same, and
FIG. 8 represents a sectional side view showing the slideable piston of FIG. 7 in an assembled condition.
In the following description and in the claims, various details are identified by specific names for convenience. These names are intended to be generic in their application. Corresponding reference characters refer to like members throughout the several figures of the drawings.
The drawings accompanying, and forming part of, this specification disclose details of construction for the purpose of explanation, but structural details may be modified without departure from the concept and principles of the invention and the invention may be incorporated in other structural forms than shown.
Referring next to the drawings and the device illustrated therein, this system as assembled for use has an outer rigid cylindrical housing, generally identified as 20 to define a tubular chamber. This housing is usually molded of a transparent or translucent plastic, with the interior of the barrel 21 providing a relatively constant bore or diameter 22. This housing 20 is contemplated as having idicia 23 to indicate the fluid volume. These indicia may be molding rings, applied painted lines and/or numbers that are conventionally provided with syringes and like housings. A precise showing of graduations of indicia 23 differs with each device, as volume and desired flow rate are particular with each such device. For example, insulin has many differing dosages, etc., and the syringes used therewith have differing indicia. In the two embodiments shown and described, the internal structures are shown to more clearly illustrate the use and construction thereof. The fragmentary illustration in FIG. 1 is representative of conventionally-applied indicia. The rear or open end of barrel 21 may be closed with a cap 24 having a skirt 25 that is a snug fit within bore 22. A vent or small aperture 26 is formed in and through this cap, with this aperture 26 allowing air to enter the interior of the barrel 21 and preventing development of negative pressure as piston 28 is slid back and forth.
This piston 28 is shown in greater detail in FIG. 3. This piston has a core 29 of substantially stiff material, such as polypropylene plastic, which retains its conformation when the elastomeric member is stretched. A tire portion 30 has right and left ribs or rings 31 and 32 which are shaped and sized to provide a minimum of friction with the interior surface 22 of the barrel 21. These rings may be of Teflon (™ duPont) or polypropylenecoated coated rubber, silicone rubber, coated neoprene and the like, or may have a treated surface to provide minimum friction while providing a seal when and while sliding. The forward face portion of this piston is formed with a spherical shape 33 to match the interior spherical configuration of a wall 34 at the front end of the housing. The forward (left) end portion of the housing is molded so as to have two coaxial tubular portions extending from the wall 34. The outer portion is generally identified as 35 and has a tapered shell 36 with a closed end 37 in which is formed a circular recess 38 for the insertion and retention of a flexible tubing conductor 40. A small aperture 42 is shown in and through the closed end 37. This small aperture may provide the desired fluid flow capability or control. This aperture provides a fluid-flow path from the interior of outer portion 35 to the interior of tubing 40.
In this outer tapered portion 36 is molded or formed a small communicating hole or aperture 46 see FIG. 4 and, for the convenience of mounting and positioning, there is shown a collar portion 48 also formed as this tapered portion 36 is molded. A resilient plug 50 is mounted in this collared portion and aperture 46. This plug provides a resilient seal which may be pierced by a needle from a syringe, not shown. Interior of tapered shell 36 is another and shorter tubular member 54 which may be integral with the molding of the barrel 21. As depicted, this member is tubular in configuration and has its outward (left) end formed with a taper to receive and retain a short length of rubber or other elastomeric tubing, identified as 56. This tubing 56 is secured coaxially in this tubular member 54 by a tapered plug 58. It is to be noted that in the integral wall portion between tapered shell 36 and tubular member 54 is a plurality of through holes 60. These holes provide fluid pathways from the interior of the housing and the cavity between shell 36 and member 54. The piston 28 is likewise provided with a through hole or aperture 62 (see FIG. 3) sized and adapted to receive the other end of tubing 56 coaxially, with another and like plug 58 securing this tubing 54 in the desired stretched condition. It is to be noted that for ease of manufacture and assembly, the tapered shell 36 is molded as a separate member and, as shown, has a shouldered joining, identified as 64, to provide a positive seating and securement. Sonic welding, cement or like means may be used and are contemplated so as to make shell 36 fluid-tight with housing 20 and with the desired strength capability.
In FIG. 5 there is depicted a luer lock device for connecting and disconnecting flexible tubing 40 to a catheter, not shown. The catheter is mounted in the patient to deliver medication in a controlled amount. As shown, a molded luer connection member 70 has threads 72 formed therein. The male tapered central portion, identified as 73, is shown with a mounted fluid restrictor 74 which has a predetermined through aperture 76. To the distal or left and at the end. of secured tube 40 is a filter disc 78. The mating winged luer cap connector is generally identified as 80 and has an eared portion 82 and a winged portion 84 providing manipulating means. This eared portion 82 is adapted to engage the threaded portion 72 and, when winged portion 84 is rotated, the male portion 73 is drawn into the connector 80 to close the aperture 76. The winged cap may be of rubber which is sufficiently resilient to act as or provide a resilient closure. It is also contemplated that a softer resilient member may be mounted in the cavity, identified as 85, to provide and insure that connector 70 is closed to a flow of fluid through conductor 40. The connector 70 and winged cap 80 utilized therewith are known and no patentable distinction is ascribed thereto.
There is also depicted an alternate construction providing an infusion delivery system adapted for high-speed automatic assembly. In this alternate embodiment, a housing, generally identified as 90, is a molding 91 and is formed with a substantially constant bore 92 to define a tubular chamber. The rear end of this molding may be closed by a cap 94 having a skirt portion 95 that is a snug fit within the bore 92. In this cap is also provided a vent or aperture 96 which allows atmospheric air to enter or that air within the barrel to be expelled so that development of negative or positive pressure within the housing does not occur when and with a sliding motion of a piston 98. This housing is formed with a forward wall 100 in which there are formed three through apertures.
A substantially central aperture is identified as 102 and is provided with an outwardly-extending collar portion having an internal configuration with a taper. Another aperture 104 is also formed with an outwardly-extending collar portion with a stepped bore and with the larger exterior bore sized to accept and retain the end of tubing 40. The other aperture is identified as 106 and is sized to accept and retain a one-way valve (not shown) or a resilient plug such as 50, shown in FIG. 4 above.
Piston 98, as depicted in the expanded view of FIG. 7, is an unassembled structure having an outer member 110 made of Teflon (™ duPont), coated rubber or silicone rubber, or a surface treated or coated to prevent sticking or sliding friction. This member 110 is provided with ribs or rings 112 and 113. Aperture 114 and enlarged aperture 115 are provided with and in this structure. A plastic molding 116 is made to fit the inside of the outer member 110. This molding has a through aperture 117, with the aperture formed with a small tapered portion adapted to receive and retain said plug when an elastomeric tubing 56 is brought into and through the aperture 117.
In FIG. 8 the piston assemby 98 is illustrated. The outer member 110 is shown with molding 116 inserted therein. The tubing 56 is inserted in and through aperture 117 and plug 118 is mounted in this end to secure and retain this tubing when and as the piston 98 is moved rearward. In FIG. 6 C the piston 98 is shown adjacent end 100. The tubing 40 is closed by the winged member 80 as in FIG. 5 above. With this conductor closed, a needle inserted through plug 50 and fluid (drugs) is flowed into the housing 90 to cause piston 98 to move rearwardly until the desired amount has been transferred. Tubing 56 is stretched to provide the desired constant tension as in FIG. 6 A. After the desired transfer (filling) has been achieved, connection to the patient is made and the piston, as moved by the stretched tubing 56, is caused to move toward end 100. The withdrawal of the needle causes the plug 50 to close and seal and, as shown in FIG. 6 B, the piston 98 is indicated as moving toward end 100. In FIG. 6 B the piston is shown midway, which is a position during filling and during the discharge of the fluid.
The assembly of the system or device of FIGS. 1 through 5 anticipates high-speed, automatic or semi-automatic assembly of the several components identified above. The housing 20 is molded of an acceptable and inexpensive plastic, such as polypropylene, that is suitable for the drug or mixture to be used therein. The piston 98 is likewise made of materials suitable for short-term life. The sealing ribs or rings 31 and 32 on the added outer rim portion 30 are designed to provide a slideable seal for the period of intended use. If desired, the one-way valve (not shown) or resilient plug 50 may be deleted in favor of a stopcock or rubber injection site provided in the tubing member.
The tubing 56 is contemplated to be an elastomeric rubber or stretchable rubber-like material. Tubing is illustrated as retained by tapered plugs 58 (FIG. 2) or 118 (FIG. 7), which is a very positive securement means. A rubber band may also be utilized, but mechanical manipulation is more easily achieved with tubing which usually and more nearly provides a constant force through a given length of stretch. When the piston is adjacent the forward end of the housing, the tubing is stretched sufficiently to insure a constant force that will move the piston alongside this forward end of the housing. In the prior art devices, the elastomeric bladder, as provided, when it approaches a relaxed condition, loses a portion of its capability to return to its "as formed" condition.
In the embodiment of FIG. 6 A through FIG. 8, the front wall 100 is substantially flat so that the apertures 102, 104 and 106 are formed easily with and around pins extending from the mold core. As the cap 94 does not come in retentive contact with the fluid to the forward side of piston 98, this cap may be of a different material from barrel 90. The housing 90 or 20 is contemplated to be of a transparent or substantially transparent material so that the user or patient may visually view the drug for clarity, contamination, etc., quantity infused or remaining, and readily determine flow rate. A flow rate is established by the aperture 76 provided in the luer lock connector 70 (FIG. 5). A winged cap 80 is conventionally provided, but other means, such as clamps, are known to shut off flow. The connector tubing may be of small bore to minimize fluid hold-up. The interior lumen may be fluted or otherwise contoured so as to prevent a seal-off due to accidental kinkage of the connector tubing.
It is contemplated that this metered delivery may also have a flow delivery connected to the tubing 40 by which an added medication, such as a pain inhibitor (killer) may be selectively delivered to the patient.
The above-depicted and -described embodiments are believed to provide a basis for a method of assembly and use of an ambulatory disposable infusion delivery system and device. This method provides the following steps of:
molding a housing with a barrel having a substantially constant bore portion and with this bore having a rear and a front end;
positioning and mounting a slideable piston within said bore and forming on this piston outwardly-directed sealing means and providing attachment means for an elastomeric force member to said slideable piston;
forming a front closure portion in the housing and providing therein means for mounting and retaining a tubular fluid conduit through which fluid may be expelled from the interior of the housing and providing a second means for securing an elastomeric force member;
providing and stretching an elastomeric or rubber-like member as the force member and attaching one end to the slideable piston and forming in said front portion a retention means for said stretched member, and
mounting a flow-control restrictor in the fluid-conduit path so as to precisely control the flow rate for the expelled fluid.
Terms such as "left," "right," "bottom," "top," "front," "back," "in," "out" and the like are applicable to the embodiments shown and described in conjunction with the drawings. These terms are merely for the purposes of description and do not necessarily apply to the position in which the infusion delivery system may be constructed or used.
While particular embodiments of the apparatus depicted for said infusion system have been shown and described, it is to be understood that the invention is not limited thereto and protection is sought to the broadest extent the prior art allows.
|Cited Patent
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|Imed Corporation
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|Mar 5, 1991
|Lefevre Robert J
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|Jun 18, 1991
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|Nov 13, 1990
|Jan 7, 1992
|Reese H William
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|Jan 17, 1991
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|Jun 10, 1992
|Mar 1, 1994
|Imed Corporation
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|May 30, 1995
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|Aug 25, 1998
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|Apr 24, 1995
|Sep 15, 1998
|Daiken Iki Co., Ltd.
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|Jan 5, 1996
|Feb 16, 1999
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|Apr 15, 1998
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|Multi-dose infusion pump
|Sep 30, 1997
|Jul 18, 2000
|Becton, Dickinson And Company
|Dampening devices and methods for needle retracting safety vascular access devices
|May 27, 1999
|Oct 31, 2000
|Situs Corporation
|Method and apparatus for placement and activation of a medical device within a body cavity
|Mar 11, 1998
|Jan 9, 2001
|Situs Corporation
|Intravesical infuser
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|Thomas F. Winters
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|Mckinley Medical, Lllp
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|Baxter International Inc.
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|Jack Y. Zhang
|Controlled medicament security enclosure system
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|Baxter International Inc.
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|Feb 23, 2002
|Jan 20, 2004
|Stryker Instruments
|Integrated medication delivery system
|Jan 21, 2003
|Sep 7, 2004
|Yong-Nyun Kim
|Liquid supply apparatus
|Aug 22, 2001
|Oct 12, 2004
|Breg, Inc.
|Medication delivery system having selective automated or manual discharge
|Sep 4, 2002
|Jun 21, 2005
|Stryker Instruments
|Port assembly for an integrated medication delivery system
|Sep 3, 2004
|Nov 15, 2005
|Yong-Nyun Kim
|Liquid supply apparatus
|Sep 4, 2002
|May 23, 2006
|Stryker Instruments
|Pump assembly for an integrated medication delivery system
|Sep 2, 2004
|Dec 18, 2007
|Breg, Inc.
|Medication delivery system having selective automated or manual discharge
|Feb 6, 2003
|Jan 13, 2009
|E-Wha Fresenius Kabi Inc.
|Liquid supply apparatus
|Nov 4, 2003
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|Stryker Corporation
|Medication delivery system comprising a combined medication reservoir, pump assembly and an actuator allowing continuous fluid communication through the pump assembly
|Sep 21, 2004
|Apr 21, 2009
|Lma North America, Inc
|System and method for tension-activated fluid control
|Jul 30, 2004
|May 5, 2009
|Lma North America, Inc.
|Medication infusion and aspiration system and method
|Aug 18, 2006
|May 25, 2010
|Stryker Corporation
|Infusion assembly that simultaneously delivers therapeutic fluid to plural body sites
|May 29, 2009
|Oct 12, 2010
|Sta-Med, Llc
|Needle cover assembly for a syringe
|Mar 15, 2005
|Jul 26, 2011
|Dali Medical Devices Ltd.
|Medicinal container engagement and automatic needle device
|May 17, 2004
|Jul 26, 2011
|E-Wha Fresenius Kabi Inc.
|Gas generating device and use of the device in continuous liquid supply
|Jun 23, 2010
|Apr 24, 2012
|Sta-Med, Llc
|Automatic-locking safety needle covers and methods of use and manufacture
|Mar 21, 2008
|Jul 24, 2012
|Baxter International, Inc.
|Fluid delivery system and flow control therefor
|Mar 21, 2008
|Jul 31, 2012
|Baxter International, Inc.
|Fluid delivery system and flow control therefor
|Jul 14, 2008
|Dec 11, 2012
|Stryker Corporation
|Method of controlling a medication delivery system with a removable label containing instructions for setting medication delivery rate overlying a second label with patient instructions
|Sep 15, 2004
|Feb 19, 2013
|Elcam Medical Agricultural Cooperative Association Ltd.
|Automatic injection device
|May 30, 2012
|Mar 4, 2014
|Sta-Med, Llc
|Blood collection safety devices and methods of use and manufacture
|Mar 21, 2008
|Mar 18, 2014
|Baxter International Inc.
|Fluid delivery system and flow control therefor
|Apr 16, 2012
|Jun 10, 2014
|Sta-Med, Llc
|Automatic-locking safety needle covers and methods of use and manufacture
|Mar 15, 2013
|Apr 26, 2016
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|Devices and methods for modulating medium delivery
|Feb 20, 2014
|Sep 20, 2016
|Sta-Med, Llc
|Blood collection safety devices and methods of use and manufacture
|Mar 15, 2013
|Mar 28, 2017
|Mark A. D'Andrea
|Radiation treatment sheet devices and methods
|Jul 25, 2011
|Jun 13, 2017
|Becton, Dickinson And Company
|Infusion reservoir with push-on connector features and/or attachments therefor
|May 27, 2014
|Jul 4, 2017
|Sta-Med, Llc
|Automatic-locking safety needle covers and methods of use and manufacture
|Sep 4, 2002
|Dec 26, 2002
|Diaz Luis A.
|Port assembly for an integrated medication delivery system
|Jan 21, 2003
|Sep 11, 2003
|Yong-Nyun Kim
|Liquid supply apparatus
|May 8, 2003
|Sep 18, 2003
|Medrad, Inc.
|Syringes, syringe tubing and fluid transfer systems
|Jun 13, 2003
|Feb 19, 2004
|Jason Toman
|Integrated medication delivery system
|Nov 4, 2003
|Jun 3, 2004
|Diaz Luis A.
|Integrated medication delivery system
|May 17, 2004
|Jan 13, 2005
|Yong-Nyun Kim
|Gas generating device and use of the device in continuous liquid supply
|Sep 3, 2004
|Mar 17, 2005
|Yong-Nyun Kim
|Liquid supply apparatus
|Feb 6, 2003
|Sep 22, 2005
|Yong-Nyun Kim
|Liquid supply apparatus
|Aug 18, 2006
|Dec 14, 2006
|Stryker Corporation
|Infusion assembly that simultaneously delivers therapeutic fluid to plural body sites
|Sep 21, 2004
|Apr 5, 2007
|Marc Yap
|System and method for tension-activated fluid control
|Mar 21, 2008
|Oct 2, 2008
|Jacobson James D
|Fluid delivery system and flow control therefor
|Mar 21, 2008
|Oct 2, 2008
|Jacobson James D
|Fluid delivery system and flow control therefor
|Mar 21, 2008
|Oct 16, 2008
|Jacobson James D
|Fluid delivery system and flow control therefor
|Jul 14, 2008
|Nov 6, 2008
|Stryker Corporation
|Method of controlling a medication delivery system with a removable label containing instructions for setting medication delivery rate overlying a second label with patient instructions
|Mar 25, 2009
|Jul 16, 2009
|Lma North America, Inc
|Medication infusion system and method
|Mar 24, 2009
|Jul 16, 2009
|Lma North America, Inc.
|System and Method for Tension-Activated Fluid Control
|Aug 7, 2008
|Aug 6, 2009
|Krumme John F
|Apparatus and methods for injecting dermal fillers
|May 29, 2009
|Dec 3, 2009
|Sergio Rubinstein
|Needle cover assembly for a syringe
|Oct 21, 2009
|Apr 22, 2010
|Godfrey Mark W
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|Nov 12, 2008
|May 13, 2010
|Baxter International Inc.
|Prefillable constant pressure ambulatory infusion pump
|Jun 23, 2010
|Nov 25, 2010
|Sta-Med, Llc
|Needle cover
|Feb 8, 2012
|Mar 13, 2014
|Becton ,Dickinson and Company
|Insulin Infusion Set
|Mar 15, 2013
|Sep 18, 2014
|Mark A. D'Andrea
|Radiation treatment sheet devices and methods
|Jul 18, 2014
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|Science Incorporated
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|Feb 11, 2000
|Aug 17, 2000
|Science Incorporated
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|U.S. Classification
|International Classification
|Cooperative Classification
|European Classification
|Dec 12, 1989
|Certificate of correction
|Oct 21, 1992
|Maintenance fee reminder mailed
|Nov 6, 1992
|Fee payment
Year of fee payment: 4
|Nov 6, 1992
|Surcharge for late payment
|Oct 29, 1996
|Maintenance fee reminder mailed
|Mar 23, 1997
|Lapse for failure to pay maintenance fees
|Jun 3, 1997
|Expired due to failure to pay maintenance fee
Effective date: 19970326


text:
|12 Nov 2012
BSOD hal.dll, ntoskrnl.exe pci.sys
Dell Studio XPS 9100
Windows 7 Home Premium, 64bit
CPU:Intel Core i7-960 processor
Memory: 12 GB
Graphics Card: ATI Radeon HD
Monitor HP pavillion vf17
Screen Resolution 1707 X 960
Hard drive: 2TB Serial ATA 2 Hard Drive 7200 RPM
3 dumps in about 2 weeks time, last two identical (hal.dll+12a3b ntoskrnl.exe+18cb13 pci.sys+9bcf). I don't do any gaming. This can happen after a startup or it can happen after computer has been on for hours. I can be writing an email or be away from the computer. One thing I have noticed about this computer since the day I bought it in 2011 is the fan(s) can get very loud, esp if downloading.
After the second of the 3 dumps (on 11/8) I downloaded and thought I installed latest Seagate Barracuda XT driver for my hard drive ST32000641AS. I say I thought I installed because the date of 6/21/2006 still shows for the driver date, which is the date it was before I did the install.
I am new at this so if I need to add more information please advise and thank you for any help. I have had similar problems in the past but was not set up for a dump so don't know if it was exactly the same. When I called Dell they told me to reinstall Windows. That is something I really do not want to do, if at all possible. That time I fumbled around downloading different things and probably did some system restores and suddenly the problem stopped. Since I really don't know what I did last time to 'fix' it I can't repeat it. And it was likely only temporary. This time I would like to get it fixed for real. I didn't call Dell this time cause I know their answer.
|My System Specs
|12 Nov 2012
I thought I did follow the instructions. I uploaded the zip file, I put the system specs that I know of in and gave an idea on what I was doing (or not doing) on the computer at the time of the dumps.
Obviously I am missing something or you would not have replied with that link, but I don't see what i am missing.
|My System Specs
|12 Nov 2012
DRIVER_POWER_STATE_FAILURE (9f) Probably caused by : nusb3hub.sys Image path: nusb3hub.sys Image name: nusb3hub.sys Timestamp: Mon Oct 26 14:19:44 2009 (4AE5B000)
STOP 0x0000009F: DRIVER_POWER_STATE_FAILURE
WHEA_UNCORRECTABLE_ERROR (124) Probably caused by : GenuineIntel
From the BSODs, some of your hardware is failing, therefore you can follow the steps within the Stop 0x124 link (post if you have any problems with the steps), also could you please update the driver referenced in the first block of code.
|My System Specs
|12 Nov 2012
Thank you, i am working on that now. Could not find a download of nusb3hub.sys so working on the Stop 0x124 steps and currently downloading OCCT 4.3.2 to check the overclocking.
|My System Specs
|12 Nov 2012
Two of the BSODs were related to Stop 0x124 BSOD, so I believe the hardware is more of a problem at the moment, than the driver itself.
|My System Specs
|16 Nov 2012
I updated the BIOS, drivers and chipset and replaced the nusb driver. But i have had the same traps and dumps the last two days as the previous two traps. The traps occur right after I boot up in the morning (computer off for about 5-6 hours). This last trap caused the machine not to want to reboot and it had to do a Start Up Repair and asked if I wanted to restore to an older version, i said yes, i was not given a selection of which version.
I am going to try to contact Dell again, even tho I have no faith in what they will say to do. (reinstall Windows). This machine still has a few days warranty. But they will not admit it is hardware even tho my fans run loud at times and my video display indicates problems from time to time.
I will update here if something miraculous happens. Thanks for your help.
|My System Specs
|16 Nov 2012
It's a hardware problem for sure! Tell Dell you had the Stop 0x124 BSOD which is strictly related to hardware issues.
Your welcome
|My System Specs
|16 Nov 2012
Will do (tell of Stop 0X124) i dont see the BSOD so i did not know what i was getting. just the dump. Their tech support is calling me in 8 minutes so we shall see. Last time i spent hours on phone with them, doing all kind of diags and they told me computer hardware was fine. Boring and not effective. Here is hoping for a better experience.
|My System Specs
|17 Nov 2012
On 11/17/12 a.m. there were two more traps, one right after the other. the first one was identical to the previous three. The last one was similar but it also included references to the netbios.sys+1b27040 and mssmbios.sys+8cfb8d8
The only difference from 11/15 trap until the 11/17 traps is that Dell support removed the McAfee antivirus and instructed me to remove my external backup harddrive, which I did. Support then said to wait and see what happens. He said this problem could be drivers (all updated), antivirus (removed), or the need to reseat a few components.
The Bios was updated on 11/12, there was a trap on 11/15 that did not refer to the BIOS. The mention of it in the second trap of 11/17 (the last one so far) is giving me concern that things may be getting worse.
The last four traps occurred immediately after a boot up, following a complete shut down a few hours prior. (computer was cooler?) I know that the last three I still had the display on while the computer is off. Tonight I will be sure to turn the display off, as well in case that is a part of the puzzle.
|My System Specs
|Thread Tools
|Similar help and support threads
0x00000124 ntoskrnl.exe ntoskrnl.exe+4a63cc BSOD Error runninganygame
i keep getting BSOD when playing game new graphics i dont know where to start when its comes to BSOD stuff 110414-10576-01.dmp 11/4/2014 10:48:39 PM 0x00000124 00000000`00000000 fffffa80`0af318f8 00000000`00000000 00000000`00000000 ntoskrnl.exe ntoskrnl.exe+4a63cc ...
|BSOD Help and Support
BSOD Address:ntoskrnl.exe+75bc0; dxgmms1.sys,ntoskrnl.exe,Ntfs.sys
Hi, to make things easier for you,below is the Bug Check String, Driver, and crash address SYSTEM_SERVICE_EXCEPTION___dxgmms1.sys___ntoskrnl.exe+75bc0 MEMORY_MANAGEMENT_______ntoskrnl.exe____ntoskrnl.exe+75bc0 SYSTEM_SERVICE_EXCEPTION___ntoskrnl.exe____ntoskrnl.exe+75bc0...
|BSOD Help and Support
BSOD when goes sleep, ntoskrnl.exe+e96d2/ntoskrnl.exe+81e7a
When I put my pc in sleep mode it often crashes: the screen goes normally in sleep mode, but the pc continues to stay awake for several minutes than BSOD & restart or BSOD & shut off. Thanks to BlueScreenView I found what is seemingly the guilty process, but I don't know what to do now. Thanks...
|BSOD Help and Support
BSOD ntoskrnl.exe , All the Time !! Crash Address ntoskrnl.exe+80640
Jan 2014 //------------------------------------------- How to Solve : 1- I've uninstalled my windows and recover my laptop with recovery DVD to it's original factory state.(original windows :)) 2- Never installed Norton internet security again , I'm using Microsoft Security Essentials now. 3-...
|BSOD Help and Support
Random BSOD Reporting ntoskrnl.exe+75c40 & ntoskrnl.exe+7efc0
I'm getting random Blue Screens and can't figure out why. I'm not running any hardcore programs. I'm mostly just using Microsoft Office and Firefox. The BSOD's seem to happen when I'm in Outlook, Excel or Firefox. Haven't been able to determine exactly which at the time as I'm moving back and...
|BSOD Help and Support
BSOD Ntoskrnl.exe+7efc0 and Ntoskrnl.exe+75c40
I keep getting a BSOD (Critical_Object_Termination) but have no idea what is causing the issue. I tried in vain to debug my own minidump files but ended up getting nowhere. So far i have run MemTest over the weekend with 107 passes. I also ran Prime95 64-bit for 4 hours on each of the FFT tests...
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text:
Added to Shopping Bag
Saint Laurent Shoulder Bag
Listed by wade howell
Price: $616.98
Returnable for site
You can request a return for Tradesy Site Credit within 4 days of delivery. FREE return shipping.
If your item was misrepresented in any way, file a Misrepresentation Claim within 4 days of delivery. Our team will review your claim and you may be eligible for a full refund.
Shopping Bag :
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This Item is No Longer Available
Shoulder Bag
Measurements: 12 x 2 x 14
$616.98 Shipping Included
Retail Price: $1,850.00
Saint Laurent Shoulder Bag
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Pay with Credit Card, PayPal, or Affirm.
This item has visible signs of wear
retail $1850
sea foam green
patent leather
side zip
double handle shoulderbag
interior is mint condition clean
exterior needs to be cleaned - front has a couple black scuff marks that need to be buffed out. back of bag has some pink spots that appear to be permanant but not visible when carried and not too bad when you see bag in person
patent leather
12"L x 2"H x 14"W
Style Tags:
Sat 11/25/17 - Wed 11/29/17 (4-8 days)
Feel free to return this item for any reason and get Tradesy Site Credit. Use your credit to buy something that makes you happy. Just a heads up, purchases outside the U.S. are Final Sale.
Submit a return request within 4 days of delivery
Pack and ship the item using our free return shipping label
Skip the return request and bring the item to your nearest within 4 days of delivery for instant Tradesy Credit.
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text:
Paperchase 3mm Satin Ribbon Spools (in Neon Orange/ Teal)
Getting This
Getting This
This smooth and soft satin ribbon in a beautiful color is perfect for finishing a whole variety of projects; ideal for the final gift wrapping flourish, perfect as a trim in your sewing and just right for craft projects like card-making or scrapbooking. Got it from paperchase in London. 3mm x 5m. 4 colors: 1) la rosa (sold) 2) neon orange 3) Teal 4) tropic blue (sold)
Raffles Place MRT Interchange (EW14/NS26), Singapore
Weekdays 10am-5.30pm
$0.50 for light items $1-1.50 for heavier items


text:
Real Estate Portal & Networking Website
- Posted
- Proposals 2
- Remote
- #4181
- Expired
Experience Level: Expert
Seeking a full time web application developer with excellent database integration skills (likely to be PHP/MySQL) to work on a property networking site. Knowledge of Google Maps and also handling of large postcode and street address databases would be an advantage. The project will include search functions, user registration and management, photo and video uploading, private messaging, and custom calendar functions.
Clarification Board
There are no clarification messages.


text:
To buy or not to buy....
Tourists are often bewildered by the dozens of 'half-priced' outlets selling theatre tickets. There are literally that many. In fact, there's even one within Leceister Square Underground Station, which captures most of the unsuspecting tourists who travel to the West End via the Tube. I'm not claiming that it's fraudulent, it's just that there are better deals up on the ground.
Now, which one should you get your tickets from? I'm sure that guide book of yours will advice you to get it from TKTS, which can be found on the South side of Leceister Square. Other than the fact that it's an established brand... well, at least on New York's Broadway, it's also the one that is least likely to sell you a ticket that will get you turn away at the door. Well, they're right.
TKTS sells only the best tickets... at half price. If the top ticket goes for 50 quid, you can have it for 25 quid with a two plus pound service charge. If, for some reason, you don't feel like having the best ticket, then you have to try your luck at the rest of the more dodgy looking counters. But don't be deceived by the large letterings and neon posters, do ask exactly how much the full price ticket cost and and where your seat is. They should be able to provide you with a seating plan. Ironically, TKTS does not show you the seating plan but they do tell you whether it's a 'good' or 'ok' seat.
Though all theatres are within walking distances, it's always good to check out the map that's just next to the TKTS counter, which shows the location of all theatres at the West End.
One more thing... you might like to watch your water consumption before the show. London's theatres are generally cosy and compact, it's not going to be pleasant if you need to excuse yourself halfway through.


text:
Cedar Shoals bolted out to a 3-0 lead over No. 3 Lakeside-Evans before holding on for a 4-4 tie against the Lady Panthers.
Karen Cureton scored a pair of goals, while Amy Trotter scored a goal and dished out an assist.
Aimee Kahn Foss added the other goal while Savannah Evans, Stephanie Mahaffey and Nina Carter all had assists.
Cedar Shoals will be back in action at home against Jackson Countyat 7:30 p.m. on Feb. 27.
Published in the Athens Banner-Herald on Thursday, February 19, 2004.
© 2017. All Rights Reserved. | Contact Us


text:
[Other SNS] Kim Jaejoong's Photos from 'The Rebirth of J' Asia Tour in Taiwan + 7 Charming Points
We start by going over behind the scenes at the last concert stop, Taiwan, then
analyze Kim Jaejoong's 7 charming points.
Taiwan Concert Behind the Scenes
Needless to say… he is so handsome. This is becoming too redundant, my mouth hurts. Flower Jaejoong
First, Kim Jaejoong did a video interview with a Taiwan media. MC Ken kept the interview go very smooth. Here is a memorable shot with him. Thank you.
Is this how this guy Kim Jaejoong enjoys solitude?
Not.. really… Kim Jaejoong is just posing for his interview photo Model force, look at his proportion, WOW
Carefully autographing
BTW, Kim Jaejoong has been worrying about something since morning of April 1
Kim Jaejoong even practiced collapsing on floor. What is this special event he prepared? Hold on till the end to find out.
Let's make tonight's event successful!
Kim Jaejoong heats up the venue with Good Morning Night as usual.
Kim Jaejoong wiped his sweat off and …
all of sudden..
Check out the video:
After the event, Jaejoong apologized sincerely to fans who were worried "Did you think it was real?"
Once the event was over, Jaejoong poured out all the energy he had left for fans who shouted, "One more time!" So cute
Final shot with the band members who had been with Kim Jaejoong Asia Tour for last 3 month "Good job everyone!"
End of Taiwan Behind the Scenes!
7 Charming Points of Kim Jaejoong start!
1. Return of the King
Preparing for the day such as tying shoes.
Heart always flutters during rehearsals before meeting fans.
Kim Jaejoong pays extra attention to detail during every rehearsal
Here we go!
Halo behind Kim Jaejoong.
Whenever JJ walks out on stage, our hearts start fluttering, we get so emotional
Kim Jaejoong always do his best on stage not withholding anything back! This is true return of king ! "Thank you for waiting for me for 2 years"
2. Baby Jaejoong
Let's see how polarizing his charms are!
Reasons why he is called BabyJJ, 3-yr-old JJ, 1-yr-old JJ, even: baby skin, pouty lips
Drinks water using straws always, because Kim Jaejoong is 3 years old
The sleeves must cover his hands just a little
3. Sexiness
Kim Jaejoong's undisputed number one charm is his sexiness!
Time to meet JJ armored with sexiness after BabyJJ
Could you let your leg down for a second?
Yes, that's it! That's what I wanted! His covered skin and fine muscles
How sexy Kim Jaejoong is on stage! People say men look sexy when working hard!
JJ's sexiness is on its own class! Be aware of nosebleed/heart thump
We are melting at Kim Jaejoong 's wink
4. Professionalism
Checks all details of interview script Rehearsal?
He checks stage floor, sound and all the movement lines
I'll come back after another great performance today!
He stops momentarily for photo
Cheer for Kim Jaejoong for 15 concerts in 9 cities.
5. Fool for his fan
Kim Jaejoong is famous for his love for fans
This tour became more unforgettable because he sang I'll Protect You with fans.
Kim Jaejoong wears jacket fans picked for him. This is truly special fan service.
Kim Jaejoong sat on stage floor because of singing Good Morning Night too many times but he keeps going at fans' One More Time' chant
Kim Jaejoong also sheds tears at fans' surprise event.
He expresses his appreciation for fans by bowing deeply and really long
I Love you everyone.
6. Global Star
Before Thailand press conference Flower Bouquet for Kim Jaejoong
Shopping mall filled with people who came to see Jaejoong's Power of Global Star
Media frenzy followed him at every city Kim Jaejoong visited
Autograph requests also
Banners written in Korean by overseas fans filled with love
Fans who fill the concert venue are proof that Kim Jaejoong is a global star, right?
7. V-LIVE App Expert
Kim Jaejoong started using V-Live only 3 months ago after discharge but became an expert!
He can't stop smiling reading fans' comments
This is Macau. Kim Jaejoongstarted V-LIVE by sharing the scenery with fans
He is expert at selfie sticks he goes on elevator with ease and cart too
Kim Jaejoong gives tour of stage for fans waiting
and doesn't forget to introduce his band. You are a true master of V-LIVE
The tour is over … (cry)
Go watch the Asia Tour 'The Rebirth of J' Behind Film
We've only just begun!! "I thank fans who stayed with me last 3 months" #김재중 Please look forward to even better JJ's return!
Source: CJeS Naver
Translated by: @Crystalmoon0213
Shared by: PrinceJJ


text:
PARKING NEAR Fabulous Fox Theater
Don't miss the start of the show because you couldn't find a parking space!
We've sourced a selection of parking options near Fabulous Fox Theater that you can reserve right now to ensure that you've got guaranteed parking for your night out.View all nearby parking
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0.94 mi away at 314 Luckie St NW
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Please note: The term Fabulous Fox Theater as well as all associated graphics, logos, and/or other tradermarks, tradenames or copyrights are the property of the Fabulous Fox Theater and are used herein for factual descriptive purposes only. We are in no way associated with or authorized by the Fabulous Fox Theater and neither that entity nor any of its affiliates have licensed or endorsed us to sell tickets, goods and or services in conjunction with their events.


text: This is the delightful Kit Rae's "Fang Of Baelin" fantasy knife. It's a special edition with a solid Black display stand.Created as though it's come from the armor and the Fangs of the Baelin. A mythical beastthat had been created by "The Dark One" in oder to provide protection and guard for his hoards of treasure.During an Epic battle the Baelin was slain and it's Fangs were removed, and along with the incredible Baelin armor, came together to create this awesome weapon.Overall the Fang Of Baelin is 7.75 inches, and features a 4 7/8 inch blade that has been intricately made from 420 J2 tempered stainless steel, sharpened on the inside edge.The handle is a cast Aluminium and looks stunning.Comes with a deep Black display stand just over 7 inches by 7 inches.