text:
KeHE to Distribute Sipp Eco Beverage Co.
PHILADELPHIA — SIPP eco beverage co., Inc., creators of the sparkling organic beverage Sipp Sparkling Organics, has announced a national distribution partnership with KeHE Distributors, LLC, the second largest distributor of natural and gourmet food products.
Distribution by KeHE will bring Sipp onto shelves in large and medium-size retail stores and markets including Fairway Markets, with locations in New York, New Jersey, and Connecticut. KeHE will also deliver Sipp to Central Market locations in Texas.
KeHE operates 12 warehouses throughout the U.S., Canada, Mexico, the Caribbean, and Central and South America, distributing over 38,400 SKUs in the natural food channel. Working with more than 3,500 manufacturers, importers, and other supply partners, KeHE has been a leading member of the natural and organic product community since 1972.
"We are very excited to be working with KeHE as it will allow us to greatly expand the availability of Sipp," said Beth Parentice, CEO/Founder. "As the demand for Sipp grows nationally, it's the right time for us to partner with a large well known distributor such as KeHE."
Sipp currently has distribution in retail stores and restaurants in California such as Bristol Farms and Andronico's. Retail stores carrying Sipp in Texas and across the East Coast include Whole Foods, Food Emporium, Central Market, Balducci's, ABC Fine Wine & Spirits, Roche Bros and now Fairway Markets.
About SIPP eco beverage co., Inc.
In late 2009, Beth Parentice set out to create a new, healthier soda alternative. After many months of mixing, testing and tasting, Sipp debuted at the Natural Products Expo in Boston and unveiled a brand new line of organic sparkling beverages sweetened with agave. Sipp has received celebrity endorsements as well as awards including Best Beverage of 2011 in Beverage World Magazine. Sipp has also been featured in FOOD & WINE Magazine as well as Martha Stewart's Whole Living Magazine. Bottles of Sipp can be found in areas where the consumer is looking for unique flavorful healthier alternatives, such as organic restaurants, markets, and cafes. Visit www.haveasipp.com for more information and where to find Sipp near you.
About KeHE Distributors, LLC
KeHE Distributors, LLC based in Naperville, IL, provides Natural & Organic, Specialty & Gourmet, International & Multicultural and Fresh products to over 30,000 retail outlets throughout North America. For more information about KeHE, visit www.kehe.com.


text:
Last week I spent 5 days learning at the feet of Dave Ramsey and his team about their philosophies on leadership. I attended their top-end event, which they call "Entreleadership Master Series". I attended solely as a student and a participant, not as a presenter.
It was without a doubt the single most valuable formal education I've ever received on Leadership. In true Dave Ramsey fashion it was inspiring, heart-warming, practical, funny, hard-hitting, and it included a very heavy dose of not-so-common common sense about running a business.
I tried very hard to boil dozens of key lessons down to my top 7 personal take-aways:
1. To Be Unclear is to be Unkind – The first question any leader must ask themselves when one of their teammates is underperforming is "are they being led properly?" – a huge part of which centers around clarity. Does the person know clearly who their leader is? Do they have documented (and signed) on 1 sheet of paper what their KRAs (Key Results Areas) and expectations are? Do they have a 1-page sheet that clearly explains all elements of their compensation plan and do they understand it well enough to explain it to their spouse? Is their leader communicating to them consistently about how they are performing compared to the expectations of their position?
2. Sanctioned Incompetence is one of the most common signs of a mediocre leader – The vast majority of organizations have people on their team that everyone knows is an underperformer. Weak leaders allow them to stay and have no game plan for resolution because they fear conflict and they have a scarcity mentality when it comes to replacing them. This destroys the culture because the spineless leader is creating an environment of "sanctioned incompetence" and what happens overtime is the thoroughbreds leave the organization because they want to be associated with and surrounded by excellence – and not mediocrity. Strong leaders demand excellence; or at least progress. Strong leaders do not fear conflict and they protect the best interest of the rest of the team by weeding out those who aren't performing at the speed of the pack.
3. Small business benefits are different from big business benefits – One of the most freeing pieces of advice from Dave was hearing "small businesses do not need to feel the pressure to provide the same benefits package as big businesses." His point was not to underserve your employees but to realize that you shouldn't risk the profitability and growth of the overall small business by feeling pressured to compete with big business benefit packages. Small businesses offer something special: an environment where people actually care about you. Small businesses can be nimble and do things to provide people with flexibility and support to show they care. And, if you hired someone who joined your team because they needed benefits then you hired the wrong person. You don't want to hire people who need benefits; you want to hire people who are crusaders of your mission.
4. Be slow and thorough to hire – Hiring the wrong person is one of the most expensive mistakes a leader can make. And yet, most leaders have so much work that needs to be done that they are typically more interested in rushing to hire a "warm body" than they are in finding the right person. Take the number of interviews you typically do and multiply it by 3. Include a mandatory interview with their spouse (to make sure they aren't married to "Crazy"). Require them to submit their personal budget so that you know they can afford to work for you. And most of all, hire people who care deeply about the work that your organization is doing! The delegation and time management challenges that leaders feel is often the result of their own under confidence in the people on their staff.
5. Overhead is the slow and subtle killer of many businesses – Do not let your overhead creep up and up. It starts to happen slowly as businesses grow because it's easy to add overhead but very hard to get rid of it. Don't be afraid to rent equipment and outsource to vendors. Even if it makes "dollar for dollar" sense to insource a task, don't forget to account for the added element of the risk of carrying the additional overhead.
6. Despite everything you hear it is very possible to build a business without using credit! – People will fight to their death on this topic trying to convince you that the only way to scale a business is with debt and it is simply not true. Sure, debt can magnify success 1 out of 10x – and these are the only stories you hear about. But 9x out of 10 debt will only magnify your mistakes. Paying with cash forces organic growth and you spend money differently when it's your money and not someone else's money. Build your business with cash! Follow the 20/50/30 rule:
a. 20% of profits should always be added to retained earnings as an "emergency fund" for your business and to use for investing in future growth.
b. 50% of profits should be used to pay down business debt to get debt free. After which you can share your profits with team members, reinvest in the future, and pocket the remaining!
c. 30% of profits (every single month) should be set aside for taxes. Do not assume that you'll "be ok" when tax time comes; plan for it every step of the way.
7. Integrity is the single most important quality of every part and every person of every business – You can't do business with people you can't trust…period.
a. When it comes to vendors…if you can't trust the guy's handshake then no contract will ever do you any good.
b. When it comes to employees…if their family can't trust them to be honest and loyal then your business most certainly can't.
c. When it comes to leaders…if a person doesn't have integrity to do what they say they're going to do and to do the right thing regardless of the cost, then they simply do not have a chance at being a successful leader.
The word "integrity" comes from the root word "integer" meaning whole. There is no separation between personal lives and professional lives. A person is both "whole" and living with integrity or they are not. It might seem silly that I had to spend 5 days with Dave Ramsey to become absolutely convicted and clear on that but it did…and that one idea alone will change the entire trajectory of my future as a leader.
My only regret was that I didn't attend Entreleadership Master Series earlier.

subset: commoncrawl


text:
Hello there
In May 2005, Carey, manager of a McDonald's in Deptford, had just one question: Who was this woman eating up the drive-through french fries?
She was Candace, who grew up in Harrisburg, had a psychology degree from Villanova University, and was a newly hired human resources specialist. As a new McDonald's corporate employee, Candace was required to spend seven weeks working at a restaurant.
Oh yes, Carey harassed her about munching at his restaurant, where the Elmer Borough native had been working since he was 16. Candace could take it - she has the same wacky sense of humor. "We say things that normal people wouldn't say, but it's all in fun," said Carey, who holds a business degree from Rowan University. Candace gave as good as she got.
When her time in Deptford was almost up, Carey had another question: Might this funny, smart, beautiful woman be interested in him?
"Maybe she is," he thought when she asked him to burn her a copy of his Mariah Carey album. "Definitely," he decided when she asked him to burn a second copy.
"I broke it," Candace told him. It was a two-CD set.
"You broke them both?"
Candace told Carey she had run them over with her car.
"It was the worst lie ever," she said recently. It was an excuse to have more conversation with this funny, handsome guy with the killer work ethic, she said.
The two kept in touch after Candace's training ended. After hanging out a few times, they knew they had found something real. A talk with a supervisor assured that Candace would never be assigned HR duties at Carey's restaurant. (Before long, it was restaurants, plural. Carey was soon overseeing half a dozen stores in the Philadelphia region.)
She's been laughing at his Michael Jackson impersonations ever since.
How does forever sound?
When they met, Candace, now 30, lived in Manayunk and Carey, now 32, in Deptford. About a year into their relationship, they got a place together in Conshohocken. Three years ago, they bought a home in Delaware.
They had been in love for the better part of four years when the 2009 holiday season rolled around. So Candace was "a little cranky" when no proposal came on a November cruise. She was even less thrilled during Christmas shopping, when they stopped at a jewelry store and she and the saleswoman tried to show Carey a ring she really liked.
"He was sitting in the chair, on his BlackBerry, typing e-mails and paying no attention," Candace said. Even the woman behind the counter seemed frustrated. "Let me just write my contact information down on this card," she said, handing it to Carey.
On Christmas day, the couple were at Candace's mother's home in Harrisburg, and everyone sat down to watch what was billed as a video from the November cruise.
"Instead of a videotape of the cruise, it was him standing in our living room," Candace said. "He was talking about how we've had a great, solid relationship . . . and he wanted to spend the rest of his life with me."
The woman who had so wanted a proposal didn't recognize it when it came.
"Why are you on the TV screen?" Candace asked Carey. "Just watch the screen, please," he said.
Before she knew it, video-Carey popped the question, and next-to-her-Carey gave her the ring she thought he had ignored at the jewelry store. Her mother served champagne, her sister cried, and then Candace jumped up and down with tears in her eyes.
It was so them
They planned to get married in September, but then came Hurricane Irene. The picture they took in the rain, with her bouquet, his boutonniere, ponchos and a "Thanks Irene!" sign, became their new save-the-date card.
The rush to reschedule vendors, the phone tree to reach guests, and the emotional letdown were not fun. But the cancellation did mean that Carey was home to bail out the basement the night the sump pump failed, thus protecting their home from potentially significant damage. "It worked out," he said.
The new date also meant the couple was able to wed on the Constitution Center's terrace, overlooking Center City, at sundown. The modern terrace and the historic view were the perfect blend of their tastes, they said.
Once inside for the reception, the couple's 110 guests saw images of themselves and each other in a giant slide show that was projected on the walls all night. Carey and Candace made certain that everyone was in at least one picture. Images of the couple showed them riding four-wheelers in Vegas and posing with Ronald McDonald.
Pictures of the couple's beloved pups, Mistro the Boston terrier and Coco the Yorkie, were at every place setting, along with a paw-print cookie and a note telling guests a donation to the SPCA had been made in their honor.
After Candace smooshed some wedding cake in her new husband's face, he heard the strains of "Fly, Eagles, Fly!" Carey was delighted when the staff wheeled in a groom's cake shaped like an Eagles helmet.
Toward the end of the reception, one of the guests picked up more than 100 pre-ordered cheeseburgers from a nearby McDonalds. The guests ate them up. "My dad ate four," Candace said.
This was unexpected
The bride's sister and a bridesmaid sneaked out of the reception to decorate the couple's hotel room with rose petals. They left fancy chocolates and champagne, and wrote "Congratulations" in lipstick on the mirror.
When Candace walked toward Carey on the terrace, "I couldn't say anything," he said. "All I could do was smile. This was what we'd been waiting for."
In the moments when Carey and Candace were waiting to be introduced as Mr. and Mrs. Burnett, Candace felt a sense of calm joy. "I was really looking forward to our future together, and happy that we could finally celebrate our marriage," she said.
Discretionary spending
A bargain: Candace's dress. She, her best friend, her sister, her mother and Carey's mother camped outside Filene's Basement in Chevy Chase, Md. for the Running of the Brides sale. They were the fourth team in line. Candace tried on about 75 dresses and got her $2,500 gown for $700.
The splurge: The couple estimates they could have saved 15 percent had they held their wedding where they did not have to pay a separate venue rental fee.
The getaway: The couple took their honeymoon trip to San Francisco and Hawaii at the time it was scheduled - so before they were actually married. Right after their wedding, they moved to Atlanta, where Candace is now the HR manager for 60 restaurants and Carey is a business consultant who oversees 30 franchises.
Behind the Scenes
The Rev. Dr. Elizabeth Frumin, Narbeth
National Constitution Center, Philadelphia
Brulee Catering, Philadelphia
Firefly Photography, Kathleen Ferry, Philadelphia
Schaffer Sound Productions, Media
Creations for Celebrations, Bear, Del.
Designed by Pronovias, purchased at Filene's Running of the Brides in Chevy Chase, Md.
Papyrus, Marlton
Do You Have the Date?
Tell us in a short e-mail – at least six weeks before your ceremony – why we should feature your love story. Send it to email@example.com. Unfortunately, we can't personally respond to all submissions. If your story is chosen, you will be contacted in the weeks before your wedding.


text:
- 51 years old
- Date of birth: Oct 19, 1961
- Date of passing: Jul 3, 2013
|Let the memory of Tevera be with us forever
Tevera Gilbert Davis, 51, a longtime resident of Granville County, passed away Wednesday, July 3rd, 2013 at her home
She was a native of Dekalb Co., Indiana and the daughter of the late Robert Eugene and Wilma Hathaway Gilbert. She was of the Baptist Faith and a manager with Verizon for many years.
Funeral services will be conducted at 1:00 PM Saturday, July 6th, 2013 in the Eakes Funeral Chapel in Creedmoor, NC by Reverend Thomas Lamm. Burial will be in Riverview Cemetery in Charlottesville, Virginia on Sunday, July 7th at 2:00 PM.
Mrs. Davis is survived by her husband of thirty years, Chester A. Davis of the home, twin girls, Skylar Davis Gallemore of Raleigh and Chandler Davis of the home, a son, Elliott Davis of the home and seven surviving siblings.
In lieu of flowers memorials may be made to Duke Childrens Hospital, 2301 Erwin Road, Durham, NC 27710.
Visitation will be held Saturday, July 6th, 2013 from 11:30 to 1:00 PM prior to the funeral service at the Eakes Funeral Home in Creedmoor.
Eakes Funeral Home is assisting the Davis family
"They told me you were gone today,
I still don't believe it's true
'cause in my mind, I still see your face
smilin' like you always do
As I walk thorugh my garden,
the flowers all in bloom
In every one, I see your face
smilin' like you always do"
"Trials and tribulations,
we've seen more than just a few
But through it all I saw your face,
smilin' like you always do
Our time together way too short
but I am glad your pain is through
And even tho, I miss you so,
I'll try to smile like you always do"
It is hard to imagine how one will be able to carry on after losing their best friend and wife. May God give you strength during this difficult time. Tevera was a special person and will be missed. "Blessed are those who mourn, for they shall be comforted." Matthew 5:4"
I extend my deepest condolences to each of you. My wife and I will monitor you all with prayer. Be encouraged in knowing that she have made a mark in many lives that will never be erased.. Earth has no sorrow that heaven cannot heal.""
"Tevera you have been taken to early but I am glad that you will not suffer anymore, can be at peace, no longer in pain. You taught me a lot. some of that has me where I am today. From my family to all of you our prayers and thoughts are with all of you. You will be able to look down from heaven with a smile known all the things that you have done in your life, bless you. Love Julie"
"While I contemplate the loss of a colleague and friend, I know that her pain is over. Tevera was always there for me and I was lucky to count her as a friend. Time will pass and the sorrow will diminish, but her memory will last for all time. Tevera was the epitome of kindness. Semper Fi, T. Miss you and wish we could have had one more talk. Nicholas"
"Tevera was a very kind lady. she was a great mom .our children grew up together from the baseball fields to graduation . It was always nice to see her smiling face at all these functions. SHE WILL SURELY BE MISSED!!! GOD BLESS MIKE &JUDY ROBBINS"
"Word can't express the loss of losing such a wonderful friend; Tevera impacted everyone she interacted with. She will be missed and never forgotten!!! I pray for comfort on the hearts of the Davis Family. You all were the light of her life and I don't think i ever had a conversation with her, where she wasn't smiling and telling a story about her family!! God Bless, Tanya Howard Smith"
to visit this memorial:
Subscribe to receive e-mail notifications when others contribute to this memorial.
Have a suggestion for us?


text: Joint/Adjunct Faculty Lab Website Ziv Bar-Joseph – Assist Professor, Carnegie Mellon University, Dept. of Computer Science Ph.D., Computer Science, Massachusetts Institute of Technology Our group develops computational methods for understanding the dynamics, interactions and conservation of complex biological systems. As new high-throughput biological data sources become available, they hold the promise of revolutionizing molecular biology by providing a large-scale view of cellular activity. However, each type of data is noisy, contains many missing values and only measures a single aspect of cellular activity. Our computational focus is on methods for large scale data integration. We primarily rely on machine learning and statistical methods. Most of our work is carried out in close collaboration with experimentalists. Many computational tools we develop are available and widely used. Navlakha and Z. Bar-Joseph. "Distributed information processing in biological and computational systems." Communications of the ACM (CACM), 58 (1), Pages 94-102, 2015. Navlakha, C. Faloutsos and Z. Bar-Joseph. "MASSEXODUS: Modeling evolving networks in adversarial environments." Data Mining and Knowledge Discovery (DAMI)," to appear, 2015 Lab Website Jaime Carbonell – Professor, Carnegie Mellon University Dept. of Computer Science PhD, MPhil, MS, Computer Science, Yale University Context-Based Machine Translation, Example-Based Machine Translation, Machine Learning in Computational Proteomics, Active and Proactive Machine Learning, Machine Learning and Language Technologies in Biomedicine (e.g. Optimizing HIV Therapy), Wind Energy Optimization. Wei-Yu, A. Kılınç-Karzan, F., and Carbonell, J., "Saddle Points and Accelerated Perceptron Algorithms", of International Conference on Machine Learning (ICML), Beijing, 2014. Flanigan, J., Thomson, S., Carbonell, J., Dyer, C., and Smith, N., "A Discriminative Graph-Based Parser for the Abstract Meaning Representation" In Proc, of the Association for Computational Linguistics Conference (ACL), Baltimore, 2014. (Best paper honorable mention). Lab Website Lillian T. Chong – Assistant Professor, University of Pittsburgh, Dept. of Chemistry Ph.D., University of California at San Francisco Development of weighted ensemble approaches for sampling "rare", but fast events (e.g. protein folding, binding, or switching) with rigorous kinetics. Simulation of protein binding pathways and kinetics. Development of simulation approaches with various levels of coarse-graining to aid the design of protein conformational switches. Debiec, K. T.; Gronenborn, A. M; and Chong, L. T. "Evaluating the strength of salt bridges – a comparison of current bimolecular force fields." Phys. Chem. B, Vol. 118, Pages 6561-6569, 2014. Suarez, E.; Lettieri, S.; Zwier, M. C.; Stringer, C. A.; Subramanian, S. R.; Chong, L. T and Zuckerman, D. M. "Simultaneous computation of dynamical and equilibrium information using a weighted ensemble of trajectories," Chem. Theory Comput., Vol. 10, Pages 2658-2667, 2014. Lab Website Gregory F. Cooper – Associate Professor of Medicine and of Intelligent Systems PhD, Medical Information Science, MD, Medicine, Stanford University His research interest is in the application of decision theory, probability theory, and artificial intelligence to address biomedical informatics research questions, with a focus on causal modeling and discovery in medicine and biology, data mining of medical databases, application of Bayesian statistics in medicine, and biosurveillance. Villamarin R, Cooper G, Wagner M, Tsui FC, Espino JU., "A method for estimating from thermometer sales the incidence of diseases that are symptomatically similar to influenza," Journal of Biomedical Informatics 46 (2013) 444-457. PMID: 23501015 Hauskrecht M, Batal I, Valko M, Visweswaran S, Cooper GF, Clermont G., "Outlier-detection for patient monitoring and alerting," Journal of Biomedical Informatics 46 (2013) 47-55. PMID: 22944172. PMCID: PMC3567774 Lab Website Lance Davidson – Associate Professor, Department of Bioengineering, Swanson School of Engineering Ph.D., Biophysics, University of California at Berkeley To integrate the biomechanics of morphogenesis across a number of size scales from subcellular generation of forces to the macroscopic forces and bulk tissue properties that guide development of the developing embryo. We want to understand, in mechanical terms, how coordinated polarized cell protrusions generate force, and how these forces are converted into tissue-scale movements. Zhou J, Pal S, Maiti S, Davidson LA., "Force production and mechanical accommodation during convergent extension," 2015 Feb 15; 142(4):692-701. Doi: 10.1242/dev.116533. PMID: 25670794 McGreevy EM, Vijayraghavan D, Davidson LA, Hildebrand JD., "Shroom3 functions downstream of planar cell polarity to regulate myosin II distribution and cellular organization during neural tube closure," Biol Open. 2015 Jan 16;4(2);186-96. Doi:10.1242/bio.20149589. PMID: 25596276 Lab Website Alexander Dömling – Professor and Chair of Drug Design, University of Groningen, Netherlands Ph.D., Multicomponent Reaction Chemistry, Technical University of Munich Our team focusses on issues in computational chemistry and drug discovery. Particularly interesting topics for us are : The study of novel mdm2/mdmx inhibitors; Drug discovery projects on various targets; Method development for new MCR scaffolds; High throughput methods development for drug discovery purpose. Patil P, Khoury K, Herdtweck E, Domling A., "MCR synthesis of a tetracyclic tetrazole scaffold," Bioorg Med Chem. 2014 Dec 20. Pii: S0968-0896(14)00869-4. Doi:10.1016/j.bmc.2014.12.021. Patil P, Khoury K, Herdtweck E, Domling A., "A universal isocyanide for diverse heterocycle syntheses," Org Lett. 2014 Nov 7;16(21):5736-9. Lab Website G. Bard Ermentrout – Professor, University of Pittsburgh, Dept. of Mathematics Ph.D., Biophysics, University of Chicago Dr. Ermentrout's research program investigates models of neural and muscle physiology. His recent focus has been on the behavior of networks of cortical-like neurons. He is interested in the dynamics of wave propagation in cortical and thalamic slice models, the olfactory lobe of the Limax, and the synchronization of cortical networks, in addition to spatial and temporal patterns in neuronal networks such as those observed during flicker stimulation and localized patterns of working memory. He also studies the effects of various ionic current and synaptic plasticity on the interactions between neural oscillators. He is the author of XPPAUT, a software platform for the simulation and analysis of nonlinear dynamical systems. Guillermo Gonzalez-Burgos, Takeaki Miyamae, Diego E Pafundo, Hiroki Yoshino, Diana C Rotaru, Gil Hoftman, Dibyadeep Datta, Yun Zhang, Mahjub Hammond, Allan R Sampson, Kenneth N Fish, G Bard Ermentrout, David A Lewis, "Functional maturation of GABA synapses during postnatal development of the monkey dorsolateral prefrontal cortex," Cerebral Cortex 06/2014; 8.31 Impact Factor. Kiyoshi Kotani, Ikuhiro Yamaguchi, Lui Yoshida, Yasuhiko Jimbo, G Bard Ermentrout, "Population dynamics of the modified theta model: macroscopic phase reduction and bifurcation analysis link microscopic neuronal interactions to macroscopic gamma oscillation," Journal of The Royal Society Interface 03/2014; 11(95):20140058. 3.86 Impact Factor. Lab Website Elodie Ghedin – Professor of Biology, Public Health, New York University Ph.D., Molecular Parasitology, McGill University, Canada Research in our group is multidisciplinary and draws upon the tools of genomics, molecular virology, and computational biology. The questions we pursue relate to pathogen emergence and adaptation. Some of our projects include 1) determining the extent, structure and underlying mechanisms of genetic variation in influenza A viruses sampled across populations and within individual hosts; 2) metagenomics approaches for the characterization from clinical samples of viruses believed to cause chronic diseases; 3) mapping of the interactome between the nematode filaria worm and its endosymbiontic bacteria Wolbachia; 4) microbiome studies of lung diseases. Lijia Cui, Lorrie Lucht, Laura Tipton, Matthew B Rogers, Adam Fitch, Cathy Kessinger, Danielle Camp, Lawrence Kingsley, Nicolas Leo, Ruth M Greenblatt, Serena Fong, Stephen Stone, John Dermand, Eric Kleerup, Laurence Huang, Alison Morris, Elodie Ghedin, "Topographical diversity of the respiratory tract mycobiome and alteration in HIV and lung disease," American Journal of Respiratory and Critical Care Medicine 01/2015; 11.04 Impact Factor. Frederic Bringaud, Matthew Rogers, Elodie Ghedin, "Identification and analysis of ingi-related retroposons in the trypanosomatid genomes," Methods in molecular biology (Clifton, N.J.) 01/2015; 1201:109-22. 1.29 Impact Factor. Lab Website Vanathi Gopalakrishnan – Asst Prof., U. of Pittsburgh, Dept of Biomedical Informatics and Intelligent Systems Program Ph.D., Computer Science, University of Pittsburgh We develop and test machine learning and pattern recognition methods for increasing scientific knowledge from biomedical data. We specialize in rule learning algorithms and variants that employ probabilistic scoring for model generation and selection. Rafael Ceschin, Ashok Panigraphy, Vanathi Gopalakrishnan, "Open-source software for temporal analysis and visualization of brain tumor diffusion MR using serial functional diffusion mapping," Cancer Informatics 2015:Suppl. 2 1-9. Balasubramanian JB, Cooper GF, Visweswaran S, Gopalakrishnan V., "Selective model averaging with Bayesian rule learning for predictive biomedicine," Proceedings of the AMIA 2014 Joint Summits in Translational Science (In Press); April 2014; San Francisco, CA, USA2014. Lab Website Graham Hatfull – Eberly Family Professor of Biotechnology, HHMI Professor Ph.D. University of Edinburgh Current lab studies: Exploring bacteriophage genomics, Exploiting mycobacteriophages, Site-specific recombination, Tools – Genetic and Clinical Pope, W. H., Jacobs-Sera, D., Russell, D. A., Rubin, D. H. F., Kajee, A., Msibi, Z. N. P., Larsen, M. H., Jacobs, W. R. Jr., Lawrence, J. G., Hendrix, R. W., & Hatfull, G. F. (2014)., "Genomics and proteomics of mycobacteriophage patience: An accidental tourist in the mycobacterium neighborhood," mBio pii: e02145-14. Doi: 10.1128/mBio.02145-14. Hatfull, G. F. (2014)., "Molecular genetics of mycobacteriophages," Microbiol Spectr. 2, 1-36. Lab Website Naftali Kaminski – Yale U, Boehringer Ingelheim Pharmaceuticals, Inc. Prof of Medicine (Pulmonary); Section Chief Medical School of Hadassah and the Hebrew University in Jerusalem Genomics; microRNAs; Non-coding RNAs; Biomarkers; Idiopathic Pulmonary Fibrosis and other Interstitial Lung Disease; Advanced Lung Disease; Personalized Medicine; Systems Biology; High-throughput technologies; Matrix Mtealloproteases Pandit KV, Corcoran D, Yousef H, Yarlagadda M, Tzouvelekis A, Gibson KF, Konishi K, Yousem SA, Singh M, Handley D, Richards T, Selman M, Watkins SC, Pardo A, Ben-Yehudah A, Bouros D, Eickelberg O, Ray P, Benos PV, Kaminski N., "Inhibition and role of Let-7d in idiopathic pulmonary fibrosis," Am J Respir Crit Care Med. 2010 Apr 15. [Epub ahead of print]. Yousem SA, Gibson K, Kaminski N, Oddis CV, Ascherman DP., "The pulmonary histopathologic manifestations of the anti-Jo-1 tRNA synthetase syndrome," Mod Pathol. 2010 Jun; 23(6):874-80. Lab Website Ossama Kashlan – Research Assistant Professor, University of Pittsburgh, Renal-Electrolyte Division PhD, University of Pennsylvania Research interests: Allosteric regulation of ion channels; Regulation of ion channels by proteases; Ion channels selectivity. Ossama B Kashlan, Brandon M Blobner, Zachary Zuzek, Michael Tolino, Thomas R Kleyman (2014) Na + Inhibits the Epithelial Na + Channel by Binding to a Site in an Extracellular Acidic Cleft Journal of Biological Chemistry 11/2014; 290(1). David Pearce, Rama Soundararajan, Christiane Trimpert, Ossama B Kashlan, Peter M T Deen, Donald E Kohan (2014) Collecting Duct Principal Cell Transport Processes and Their Regulation Clinical Journal of the American Society of Nephrology 05/2014; 10(1). Lab Website Dennis Kostka – Assistant Professor, U. of Pittsburgh Dept. of Developmental Biology Ph.D,, Computational Biology, Free University Berlin / Max Planck Institute for Molecular Genetics Research: How do different organs and tissues arise? What are the genetic and epigenetic mechanisms that drive this development? To address these questions we design statistical methods and algorithms and apply them to large-scale, genome-wide data. Ultimately, our goal is to generate, test, and confirm hypotheses that are relevant to human health. John A Capra, Dennis Kostka, "Modeling DNA methylation dynamics with approaches from phylogenetics," Bioinformatics 2014 Sep;30(17):i408-14. AK Marrone, DB Stolz, SI Bastacky, D Kostka, A Bodnar and J Ho (2014) miR-17~92 is Required for Nephrogenesis and Renal Function. Journal of the American Society of Nephrology (JASN), 25 (3). Lab Website Maria Kurnikova – Associate Professor, Carnegie Mellon University, Department of Chemistry Ph.D. Physical Chemistry, University of Pittsburgh Our research is in the area of theoretical/computational chemistry and biophysics. We are especially interested in developing functional models of membrane proteins, such as ion channels, signaling and regulatory proteins. Jose C Flores-Canales, Mauricio Vargas-Uribe, Alexey S Ladokhin, Maria Kurnikova, "Membrane association of the diphtheria toxin translocation domain studied by coarse-grained simulations and experiment," Journal of Membrane Biology 2/2015; 2.48 Impact Factor. Aysegul Ozkan, Jose C Flores-Canales, Meera Sitharam, Maria Kurnikova, "Fast and flexible geometric method for enhancing MC sampling of compact configurations for protein docking problem," 08/2014; Lab Website Christopher James Langmead – Carnegie Mellon U, Assist Prof of Computer Science. Ph.D. in Computer Science, Dartmouth College, 2003 My group has developed a number of computational methods, primarily built on probabilistic graphical models for simulating and designing molecules. Our current work focuses on: non-parametric graphical models of protein dynamics; graphical models of allosteric regulation; graphical models for simulating the emergence of drug resistance-causing mutations; graphical models for designing resistance-evading drugs. Hetunandan Kamisetty, Bornika Ghosh, Christopher James Langmead, Chris Bailey-Kellogg, "Learning sequence determinants of protein: protein interaction specificity with sparse graphical models," 01/2014;8394:129-143.Christopher James Langmead, "Generative models of conformational dynamics," Advances in Experimental Medicine and Biology 01/2014;805:87-105. 2.01 Impact Factor. Lab Website Miler Lee – University of Pittsburgh, Biological Sciences Ph.D., Genomics and Computational Biology, University of Pennsylvania My research addresses how gene expression programs change, leading to changes to cellular identity. In multicellular organisms, the genetic instructions that guide the initial stages of embryonic development are inherited from the egg as RNA. When the embryonic genome becomes active, new RNAs are transcribed, while maternally provided RNAs are destroyed. During this "maternal-to-zygotic transition," the embryo is effectively reprogrammed from an oocyte identity to pluripotency. Yartseva V, Takacs CM, Vejnar CE, Lee MT‡, Giraldez AG‡. 2016. RESA identifies mRNA regulatory sequences with high resolution. In review. Reischauer S, Stone O, Villasenor A, Chi N, Jin SW, Martin M, Lee MT, Fukuda N, Marass M, Fiddes I, Kuo T, Chung WS, Salek S, Lerrigo R, Alsio J, Luo S, Tworus D, Augustine SA, Mucenieks S, Nystedt B, Giraldez AJ, Schroth GP, Andersson O, Stainier DY. 2016. Cloche is a bHLH-PAS transcription factor that drives haemato-vascular specification. Nature 535(7611), 294-8. Lab Website Natasa Miskov-Zivanov – Assistant Professor, Electrical and Computer Engineering, University of Pittsburgh Ph.D., Computer Engineering, Carnegie Mellon University Dr. Miskov-Zivanov's research focuses on systems medicine, which represents convergence of (i) systems approach that allows for deep disease mechanism insights, (ii) emerging technologies that lead to large-scale data acquisition and provide means for new treatments, and (iii) analytic tools that can handle the complexity of the disease mechanisms, or billions of data points, and can suggest personalized therapies. N. Miskov-Zivanov, M. S. Turner, L. P. Kane, P. A. Morel, J. R. Faeder, "The duration of T cell stimulation is a critical determinant of cell fate and plasticity," in Science Signaling, 6, ra97, November 2013 [link]. N. Miskov-Zivanov and D. Marculescu, "Multiple Transient Faults in Combinational and Sequential Circuits: A Systematic Approach," in IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems (TCAD), pp. 1614-1627, October 2010 [tcad10.pdf]. Lab Website Zoltan Nagy Oltvai – Associate Professor of Pathology and Computational Biology, University of Pittsburgh, School of Medicine M.D., Semmelweiss Medical School, Budapest, Hungary Dr. Oltvai's research interest is in the area of systems biology of cell metabolism, including the metabolism of prokaryotic and mammalian cells, including tumor cells. Cobanoglu, M. C., Oltvai, Z. N., Taylor, D. L., Bahar, I., "BalestraWeb: Efficient, online evaluation of drug-target interactions," 2014 Sep 07. Cobanoglu MC, Liu C, Hu F, Oltvai ZN, Bahar I. (2013) Predicting drug-target interactions using probabilistic matrix factorization. J Chem Inf Model. 2013 Dec 23;53(12):3399-409. doi: 10.1021/ci400219z. Epub 2013 Dec 10. Lab Website John Rosenberg – Professor, University of Pittsburgh, Department of Biological Sciences My research philosophy is to bring a physical, problem-oriented approach to the acquisition and interpretation of biomolecular structural information. I view biological molecules as amazing machines that have reached the ultimate miniaturization possible in a universe composed of atoms and molecules; my approach is to pick interesting examples where it appears possible to develop understanding of how they work. Joshua L Adelman, Ying Sheng, Seungho Choe, Jeff Abramson, Ernest M Wright, John M Rosenberg, "Structural determinants of water permeation through the sodium-galactose transporter vSGLT," Biophysical Journal (Impact Factor: 3.83). 03/2014; 106(6):1280-9. DOI: 10.1016/j.bpj.2014.01.006 Seungho Choe, Joshua L. Adelman, John M. Rosenburg, Ernest M. Wright, Michael Grabe, "Understanding substrate unbinding from the sodium galactose co-transporter vSGLT based on 16 microseconds of molecular simulation," Biophysical Journal (Impact Factor: 3.83). 01/2012; 102(3):661-. DOI: 10.1016/j.bpj.2011.11.3603. Lab Website Roni Rosenfeld – Professor, Carnegie Mellon U, School of Computer Science Ph.D., Computer Science, and M.Sc., Computer Science, Carnegie Mellon University My research interests are in: (1) Forecasting Epidemics – our long term vision is to make epidemiological forecasting as universally accepted and useful as weather forecasting is today. (2) Information and Communication Technologies for Development – (ICT4D) and specifically Spoken Language Technologies for Development (SLT4D) (3) Modeling the evolution of viral epidemics. Yibin Lin, Agha Ali Raza, Jay-Yoon Lee, Danai Koutra, Roni Rosenfeld and Christos Faloutsos. Influence Propagation: Patterns, Model and a Case Study. PAKDD2014 (The 18th Pacific-Asia Conference on Knowledge Discovery and Data Mining), May 13-16, 2014, Tainan, Taiwan. Haohan Wang, Agha Ali Raza, Yibin Lin and Roni Rosenfeld. Behavior Analysis of Low-literate Users of a Viral Speech-based Telephone Service. ACM DEV-4, December 6-7, 2013, Cape Town, South Africa. Lab Website Jonathan Rubin – Professor, University of Pittsburgh, Department of Mathematics Ph.D. in Applied Mathematics from Brown University Pattern formation in networks of coupled neural oscillators; Waves and localized activity generated through nonlocal interactions; Network dynamics in the basal ganglia, with implications for motor disorders, particularly Parkinson's disease; Mechanisms and implications of synaptic plasticity, particularly spike-timing-dependent plasticity; Geometric singular perturbation theory and its relation to oscillations and bifurcations; Stability of solutions to parabolic systems of partial differential equations and related equations Wei W, Rubin JE, Wang XJ. Role of the Indirect Pathway of the Basal Ganglia in Perceptual Decision Making. J Neurosci. 2015 Mar 4;35(9):4052-4064. R. Rosenbaum, A. Zimnik, F. Zheng, R.S. Turner, C. Alzheimer, B. Doiron, and J.E. Rubin, "Axonal and synaptic failure suppress the transmission of firing rate oscillations, synchrony, and information during high frequency deep brain stimulation", Neurobiol. Disease, 62:86-99, 2014. Lab Website Gordon Rule – Professor, Biological Sciences, Carnegie Mellon University Ph.D., Biological Sciences, Carnegie Mellon University My research is directed at understanding inter-molecular interactions in biological systems. Our research efforts have been directed at enzyme-substrate interactions, protein-lipid interactions, antibody-antigen interactions, RNA structure, and protein-nucleic acid interactions. Sinha K1, Jen-Jacobson L, Rule GS. Divide and conquer is always best: sensitivity of methyl correlation experiments. J Biomol NMR. 2013 Aug;56(4):331-5. doi: 10.1007/s10858-013-9751-9. Epub 2013 Jun 15. Senutovitch N, Stanfield RL, Bhattacharyya S, Rule GS, Wilson IA, Armitage BA, Waggoner AS, Berget PB. A variable light domain fluorogen activating protein homodimerizes to activate dimethylindole red. Biochemistry. 2012 Mar 27;51(12):2471-85. Epub 2012 Mar 14. Lab Website Hanna Salman – Assistant Professor, Department of Physics & Astronomy Ph.D., Weizmann Institute of Science My research aims to understand the mechanisms of collective behavior and variability in bacterial cultures and their effect on the response of bacteria to changes in the environment. By studying the changes in the behavior of bacteria as a function of their concentration, I am able to detect some of the collective mechanisms that govern the bacterial behavior and allow them to better endure environmental stress (e.g. temperature and chemical). I utilize various optical microscopy techniques to observe the swimming pattern of bacteria under different conditions. As for the expression level of proteins, proteins of interest are labeled with fluorescent markers and the expression level is measured using fluorescence microscopy or flow cytometry. "Bacterial Thermotaxis by Speed Modulation", Mahmut Demir, and Hanna Salman, Biophysical Journal, 103, 1683–1690 (2012). "Universal Protein fluctuation in Populations of Microorganisms",Hanna Salman, Naama Brenner, Chih-kuan Tung, Noa Elyahu, Elad Stolovicki, Lindsay Moore, Albert Libchaber, and Erez Braun, Phys. Rev. Letters, 108, 238105 (2012). Lab Website Mahadev Satyanarayanan – Carnegie Group Professor, School of Computer Science, Carnegie Mellon University Ph.D., Computer Science, Carnegie Mellon University As an experimental computer scientist, I design, implement, and evaluate systems. My research interests span mobile computing, pervasive computing and distributed systems (especially distributed file systems). Performance, availability, security, usability and manageability are some of the key attributes that I pay attention to in my work. Kiryong Ha, Zhuo Chen, Wenlu Hu, Wolfgang Richter, Padmanabhan Pillai, Mahadev Satyanarayanan .Towards wearable cognitive assistance. 06/2014; DOI: 10.1145/2594368.2594383 Wolfgang Richter, Canturk Isci, Benjamin Gilbert, Jan Harkes, Vasanth Bala, Mahadev Satyanarayanan. Agentless Cloud-wide Streaming of Guest File System Updates. Proceedings of the 2nd IEEE International Conference on Cloud Engineering, IC2E, Boston, Massachussettes; 03/2014 Lab Website Jason Shoemaker – Assistant Professor, University of Pittsburgh, Chemical/Petroleum Engineering DPhil, Chemical Engineering, University of California, Santa Barbara COMPUTATIONALLY DRIVEN DISCOVERY IN HEALTH Biological information – from molecular events to personal genomics – has exploded. Our group aims to develop computational approaches to exploit large-scale data to promote disease treatment discovery and optimization. Zhao D, Fukuyama S, Sakai-Tagawa Y, Takashita E, Shoemaker JE, Kawaoka Y (2015) C646, a novel p300/CREB-binding protein-specific inhibitor of histone acetyltransferase, attenuates influenza A virus infection Antimicrob Agents Chemother Lopes, T.J.S, Shoemaker, J.E., Matsuoka, Y., Kawaoka, Y., Kitano, H. (2015) Identifying problematic drugs based on the characteristics of their targets Front. Pharmacol. Lab Website Alexander Sorkin – Professor and Chair, University of Pittsburgh, Dept. of Cell Biology and Physiology Ph.D., Cell Biology, Institute of Cytology,Academy of Sciences of the U.S.S.R. B.A., Biology and Chemistry, Leningrad Pedagogical Institute, Leningrad, U.S.S.R. My research focuses on the mechanisms of endocytosis of growth factor receptors and neurotransmitter transporters, and the role of endocytosis in regulation of the function of these proteins. We use systems biology approaches to address basic questions of cell biology. We are also interested in the quantitative image analysis and computational modeling of endocytosis and signaling networks. Goh, L. K., and Sorkin, A. (2013) Endocytosis of receptor tyrosine kinases. Cold Spring Harb Perspect Biol 2013;5:a017459. Fortian, A. and Sorkin, A. Live cell fluorescence imaging reveals high stoichiometry of Grb2 binding to the EGF receptor sustained during endocytosis. (2014) J. Cell Sci. 127:432-44. Epub 2013 Nov 20. Lab Website Robert Swendsen – Professor, Physics, Carnegie Mellon University Ph.D., Physics, University of Pennsylvania My main area of research is solid state physics and statistical mechanics, with an emphasis on computer simulations. I have worked especially on thermodynamic phase transitions combining computer simulations with a renormalization-group analysis. I have also been involved in the development of new algorithms for more efficient simulations, to enable the study of problems that would otherwise involve prohibitively long computer runs. Robert H. Swendsen, Unnormalized probability: A different view of statistical mechanics, Am. J. Phys. 82, 941 (2014) Roberta L. Klatzky, Pnina Gershon, Vikas Shivaprabhu, Randy Lee, Bing Wu, George Stetten, Robert H. Swendsen, A model of motor performance during surface penetration: from physics to voluntary control, Experimental Brain Research 230, 251 (2013) Lab Website David Swigon – Assistant Professor, U of Pittsburgh, Dept. of Mathematics Ph. D.and M.S., Theoretical Mechanics, Rutgers University, Piscataway, NJ. Mgr., Applied Mathematics(equivalent of M.S.), Charles University, Prague, Czech Republic My research interests are in the area of mathematical biology, in particular, construction of mathematical models of biological systems within the framework of theories of continuum mechanics, dynamical systems, and stochastic dynamics. Structure of the Lac Repressor-DNA Complex; Flexible docking of DNA to RNA polymerase; Control of transcription by designed DNA bending drugs; Naturally Discrete Model for DNA; Theory of Elastic Rods and Its Application to DNA T. Stepien & D. Swigon, Traveling waves in one-dimensional elastic continuum model of cell layer migration with stretch-dependent proliferation, SIADS, 13, 1489–1516 (2014). E. Mochan, D. Swigon, G.B. Ermentrout, S. Lukens, & G. Clermont, A mathematical model of intrahost pneumococcal pneumonia infection dynamics in murine strains, J. Theor. Biol., 353, 44–54 (2014). Lab Website Pei Tang – Professor of Anesthesiology, Pharmacology and Chemical Biology, & Computational Biology PhD, Physical Chemistry, SUNY at Stony Brook Determination of high-resolution domain structures of neuronal ion channels, such as nicotinic acetylcholine and glycine receptors. Characterization at the molecular level of how low-affinity drugs, particularly general anesthetics and alcohols, affect the functions of transmembrane ion channels. The approaches used in Dr. Tang's laboratory include high-resolution NMR and large-scale molecular dynamic simulations. Tillman T, Seyoum E, Mowrey D, Xu Y, Tang P. ELIC-α7 nAChR Chimeras Reveal a Prominent Role of the Extracellular-Transmembrane Domain Interface in Allosteric Modulation. J Biol Chem. In press (2014) Mowrey D, Kinde MN, Xu Y, Tang P. Atomistic Insights into Human Cys-loop Receptors by Solution NMR, Biochim Biophys Acta, in press, (2014) Lab Website George C. Tseng – Assistant Professor, U of Pittsburgh, Dept. of Biostatistics ScD, Biostatistics, Harvard University; MS, Mathematics, National Taiwan University We are a statistical group with major applications on genomics and bioinformatics. Our vision is to develop rigorous, timely and useful statistical and computational methodologies to help understand disease mechanisms and improve disease diagnosis and treatment. Ying Ding, Shaowu Tang, Serena G. Liao, Jia Jia, Steffi Oesterreich, Yan Lin, George C. Tseng. (2014) Bias correction for selecting the minimal-error classifier from many machine learning models. Bioinformatics. 30(22):3152-8. Serena G. Liao, Yan Lin, Dongwan D. Kang, Naftali Kaminski, Frank C. Sciurba, George C. Tseng. (2014) Missing value imputation in high-dimensional phenomic data: Imputable or not? And how? BMC Bioinformatics. 15:346. Lab Website Ben Van Houten – Professor, Pharmacology and Chemical Biology PhD (Biomedical Sciences – Genetics), Oak Ridge Graduate School of Biomedical Sciences/University of Tennessee The Van Houten laboratory studies the formation and repair of DNA damage in nuclear and mitochondrial genomes. We are particularly interested in the structure and function of proteins that mediate nucleotide excision repair and the role of oxidative stress in human disease. Research interests include: Structure-function Studies of Nucleotide Excision Repair Proteins, Mitochondrial DNA Damage & Repair Qian W, Salamoun J, Wang J, Roginskaya V, Van Houten B, Wipf P. "The combination of thioxodihydroquinazolinones and platinum drugs reverses platinum resistance in tumor cells by inducing mitochondrial apoptosis independent of Bax and Bak." Bioorg Med Chem Lett. 2015 Feb 15;25(4):856-63. doi: 10.1016/j.bmcl.2014.12.072. Epub 2014 Dec 30. Wang J, Li J, Santana-Santos L, Shuda M, Sobol RW, Van Houten B, Qian W. "A novel strategy for targeted killing of tumor cells: Induction of multipolar acentrosomal mitotic spindles with a quinazolinone derivative mdivi-1." Mol Oncol. 2015 Feb;9(2):488-502. doi: 10.1016/j.molonc.2014.10.002. Epub 2014 Oct 17. Lab Website Yoram Vodovotz – Director, Center for Inflammation and Regenerative Modeling, Professor of Surgery, Immunology, Communication Sci and Disorders, and Comp Biology U of Pittsburgh PhD, Immunology, Cornell University Graduate School of Medical Sciences Dr. Vodovotz's research interests include the biology of acute inflammation in shock states (e.g. septic and hemorrhagic shock) as well as in chronic diseases and wound healing. He is also interested in the cross-regulation of the inducible nitric oxide synthase and the cytokine transforming growth factor-b1 in various disease states, including malaria infection, cancer, sepsis, and neurodegenerative diseases. His main current area of interest revolves around the use of mathematical modeling to unify and gain insight into the plethora of biological interactions that characterize these inflammatory conditions. Complex Systems and Computational Biology Approaches to Acute Inflammation. An, G.; Vodovotz, Y., eds. New York, NY: New York, NY: Springer. 2013. http://dx.doi.org/10.1007/978-1-4614-8008-2 Solovyev, A.; Mi, Q.; Tzen, Y-T.; Brienza, D.; Vodovotz, Y. Hybrid equation- / agent-based model of ischemia-induced hyperemia and pressure ulcer formation predicts greater propensity to ulcerate in subjects with spinal cord injury. PLoS Comput. Biol. 2013. 9:e1003070. Lab Website Alan Wells – Thomas J Gill III Professor of Pathology M.D., Brown University The Wells' Lab research program, in close collaboration with its research partners, aims to understand cell migration in terms of how motility processes are regulated, and understand how this regulation of migration plays a role in physiologic and pathologic situations. Khanna D, Mittoo S, Aggarwal R, Proudman SM, Dalbeth N, Matteson EL, Brown K, Flaherty K, Wells AU, Seibold JR, Strand V. Connective Tissue Disease-associated Interstitial Lung Diseases (CTD-ILD) – Report from OMERACT CTD-ILD Working Group. J Rheumatol. 2015 Mar 1. pii: jrheum.141182. Furukawa M, Wheeler S, Clark AM, Wells A. Lung epithelial cells induce both phenotype alteration and senescence in breast cancer cells. PLoS One. 2015 Jan 30;10(1):e0118060. doi: 10.1371/journal.pone.0118060. eCollection 2015. Lab Website Xiang-Qun (Sean) Xie – Professor, U of Pittsburgh, Dept of Pharmaceutical Sciences and Drug Discovery Institute, Associate Dean of the School of Pharmacy, Director of CDAR and CCGS centers Ph.D., Medicinal Chemistry, School of Pharmacy, University of Connecticut, CT Xie's group focuses on development of diseases-specific chemogenomics knowledgebase, an integrated platform of "Big Data to Knowledge" target identification and system pharmacology for drug discovery translational research. The innovation includes GPU-accelerated cloud computing machine-learning TargetHunter programs for drug target identification and system pharmacology. His lab was the first discovered/patented INK4C-targeting small molecule inhibitors for hematopoietic stem cell expansion (Nature Comm 2015), and was the first discovered/patented p62ZZ chemical inhibitors for multiple myeloma (Nature Leukemia 2015) . Liu, HB, Wang, L, Su, WW and Xie* X-Q, "ALzPlatform: An Alzheimer's Disease Domain-Specific Chemogenomics Knowledgebase for Polypharmacology and Target Identification Research." J Comput Info Modeling. 2014, 54(4):1050-60. (cover page story) Wang L, Ma C, Wipf P, Liu H, Su W and Xie* X-Q. "TargetHunter: An In Silico Target Identification Tool for Predicting Therapeutic Potential of Small Organic Molecules Based on Chemogenomic Database". AAPS J. 2013, 15, 395-406 PMID:23292636 (AAPS Special Theme Issue) Lab Website Eric Xing – Professor, Carnegie Mellon University, Department of Computer Science PhD,Computer Science, U.C. Berkeley; PhD, Molecular Biology, Rutgers University, NJ My principal research interests lie in the development of machine learning and statistical methodology, and large-scale computational system and infrastructure, for solving problems involving automated learning, reasoning, and decision-making in high-dimensional, multimodal, and dynamic possible worlds in social and biological systems. Jinhui Yuan, Fei Gao, Qirong Ho, Wei Dai, Jinliang Wei, Xun Zheng, Eric P. Xing, Tie-Yan Liu, Wei-Ying Ma, LightLDA: Big Topic Models on Modest Compute Clusters , Manuscript, arXiv:1412.1576, communicated 4 Dec 2014. Xun Zheng, Jin Kyu Kim, Qirong Ho and E. P. Xing, Model-Parallel Inference for Big Topic Models, Manuscript, arXiv:1411.2305, communicated 10 Nov 2014. Lab Website Da Yang – Assistant Professor, Pharmaceutical Sciences M.D., Harbin Medical University in China; Ph.D., Pharmacology and Genomics The research of Dr. Yang's laboratory is focusing on using integrated genomic and functional studies to identify mechanisms of resistance to cancer therapeutics, and to develop novel approaches/markers to enable personalized cancer medicine. Comprehensive molecular characterization of human colon and rectal cancer Cancer Genome Atlas Network, Nature 487 (7407), 330-337 The cancer genome atlas pan-cancer analysis project JN Weinstein, EA Collisson, GB Mills, KRM Shaw, BA Ozenberger, …, Nature genetics 45 (10), 1113-1120 Lab Website Daniel M. Zuckerman – Professor, Oregon Health & Science University, Dept of Biomedical Engineering Ph.D. in Physics, University of Maryland, College Park Research: Computational Study of Protein Binding, Allostery, and Molecular Machines. Molecular-level biology is inherently dynamic. The Zuckerman group pursues ensembles of protein structures and pathways of conformational change that play a key role in binding, allostery and molecular machines. The group has been active in developing scale-free "weighted ensemble" (WE) software, which is now in use around the world. Zuckerman and colleagues developed WE methods for sampling steady-state and equilibrium conditions that have been applied to all-atom protein binding and to highly complex systems biology models of cell signaling. Accurate estimation of protein folding and unfolding times: Beyond Markov state models, Suárez, Ernesto; Adelman, Joshua; Zuckerman, Daniel*, Journal of Chemical Theory and Computation, 12:3473–3481 (2016). Biophysical comparison of ATP synthesis mechanisms shows a kinetic advantage for the rotary process, Ramu Anandakrishnan, Zining Zhang, Rory M. Donovan, and Daniel M. Zuckerman*, Proceedings of the National Academy of Sciences, 113: 11220–11225 (2016).


text:
So where i work and have always worked, sex work is illegal. South Australian laws are really old and confusing and most of us are not entirely sure exactly where we stand. And even when we do know and understand the presice ancient legal word of the law, it's the policing tactics that have a bigger impact on our daily lives, and they can change without rhyme or reason. Or maybe there is a reason that im just not aware of. Or maybe i have suspicions about possible reasons, but i aint writing it here. Or maybe there is no rhyme or reason. But the changing faces and farces of the South Australian Police is a story for another occasion.
This is the story of my first raid. I was 18. A receptionist in a massage parlour. I used to make $80 for 10 hours plus $2 for every job the business did. Kind of like a commission. It seemed like good money at the time, cash, no experience necessary. I mostly enjoyed my job there. Loved the other workers. Hated the bosses, but even back then i stood up for my rights and that of my colleagues.
It was during an era when brothel raids in Adelaide were insane. It was not uncommon for some brothels to have up to 3 major raids in a night, some workers clocked up to 50 separate charges of "being on premises in a 12 month period. One of my friends now has 84 counts of "being on premises" on her criminal record.
In an attempt to avoid this kind of police harassment this parlour was a very "straight" parlour. It was a health center that offered massages. Well that was the mask we wore. I would quote prices for a "full body massage" to potential clients over the phone or in person. Full body massage is code for massage with a happy ending. But if the potential clients didnt understand the secret language, we were in no position to educate them! We had to be careful, any client could be a cop. Not until the workers had undressed them would we know for a fact that they were not going to bust us.
My job was to answer the phone, greet clients, take money for the services, fold towels and clean spa's.
I knew how to play it safe. It was drilled into me. My arrogant bosses would sit beside me and listen to every word i said on the phone yelling at me if i said anything they decided was putting us at risk of the cops. One day i even remember him threatening to 'slit my throat from ear to ear' if i got us in trouble. I wasnt scared of him, he was just a prick. But i didn't really think about it much further than that. I was just a receptionist right? And plus our boss promised to look after us with the best lawyers if the worst should happen.
One day a woman came in for a job interview. She hadn't worked before and my boss interviewed her. She was meant to be interviewed by the other business partner but my hot shot boss wanted to play the hero and interview the new girl, so he came in on his day off. She was the second woman that week who had been interviewed. I remember it well, he was showing off, bragging to her about how busy we were, showing her our booking sheet, telling her all our secrets.
She was a cop.
So was the other woman who came in for an interview.
The cops had been watching to see which bossman worked on what days and sent in undercover cops posing as women looking for work on different days trying to entrap both men. Haha. I still find it amusing that my boss was trying to be the big man and it made him get busted twice. Its the only amusing thing about the situation.
The undercover female cops came for the interviews and left without incident, not revealing they were cops, promising to call for a roster. Two days after the second interview i was showing a client in when there was a pounding on the door. I froze. They banged and hit the doors screaming "THIS IS THE POLICE! OPEN UP! THIS IS A RAID!"
Before i got to the door, they had managed to get the door open themselves and were storming in. Immediately we were all separated and then began a very long, lonely, scary 20 minutes.
They had stormed into all the workrooms, separated clients and workers, leaving workers alone while they bullied the clients into making statements against us. Threats like "you better tell us what you were doing here or we'll go discuss this at your workplace" would have some clients giving us up in a second. Unfortunately this was one of those clients.
When the police finally got to me, they had one of the clients with them. They gathered us workers in a room. The main cop asked the client "which is the one who took her top off?" the client pointed at Melissa. "which is the one you paid the money too?" The client pointed at me.
It took 6 weeks for me to receive my summons in the mail with a court date to respond to charges of:
"receive money in a brothel"
"be on premises of a brothel"
"keep brothel"
I never heard form the bosses again, so much for their promises of the best lawyers.
I live with those charges against my name.
But at least i wasn't arrested and held without bail. That's a raid for a different story.


text:
We installed new upload servers! We're sure you've seen the improvement in upload processing because we're seeing record upload levels. Please let us know if you're having issues with uploads at firstname.lastname@example.com . Thanks for the files!On a different front, you've probably seen that we've raised email sharing limits. We're proud to say that our new db is ably handling the increased traffic. Please keep sharing!
As always, thanks for your continued support and your business!
At the time of writing comments are active on the Mediamax blog, so you may be able to give your feedback, but be quick.


text:
Well well well, a snazzily outfitted little bistro with a very economical brunch menu, no crowds, just a walk from my house? Don't mind if I do... I'd walked past the place a few times in town, and a short while ago someone on the board brought up that they served brunch on Sundays. I'd also seen it featured on a certain *mysterious* local restaurant review television show and I liked the chef's attitude: genuine and thoughtful. So we rocked over to the bistro this past weekend for some hot brunch action.
The place was busier in the front section, in front of the bar, which is backed by a sectional wall of pale green, frosted glass. The back section was nearly deserted and my dining companion and I were seated in one of the amply proportioned booths (could seat 6, no trouble). Dark wood, black (marble?) tabletops, and an inoffensively-volumed mix of music, from generic dance beats to jazz standards. Tap water was brought promptly, along with a pair of yeasty rolls with butter. Staff was capable if unremarkable, and kept the water and the coffee coming (huzzah). I ordered the crab cakes "benedict," very reasonable at $12, accompanied by house potatoes. Crab cakes were very tasty--they weren't made with big lumps of crab, as has been pointed out here in the past, but they were delicate and tasty nonetheless--and the eggs were perfectly poached. The hollandaise was tangier than I remember hollandaise being, but I think that reflects more on my hollandaise inexperience. The potatoes were the only weak element: they had a good moderate spice, included onion, and had a higher-than-average salt level, but they were a little...damp--like they'd been boiled, tossed in spice, and left in a pile. Too bad. My DC had the stuffed french toast, a total tower of power for only $9. Three thick texas toasts schmeared with mascarpone cheese (and did I detect a hint of maple in the mascarpone? I certainly hope so...) and topped with blueberry compote and a few peach wedges. Were the peach wedges canned? I fear so. Was the dish amazingly sweet and delicious? Yes. Her only complaint with the meal was her orange juice: it was akin to college dining services OJ, served from a spraying machine and containing no pulp. The juice didn't match the decor, for sure. I also missed a brunch cocktail menu--there was a martini list that had a few contenders, and I probably could have ordered one if I wanted one, but without the suggestions I defaulted to coffee.
The brunch menu is pretty limited, but if the two things we had are any indication, it's about quality and not quantity. The price is definitely right, and I plan to go again and again. With the large back seating area nearly vacant for our entire visit, I got the feeling that perhaps a girl could show up with her Sunday Times and linger over a relaxed brunch and cuppa coffee.


text:
Speaking of bad days.....two Mondays ago, I woke up and I was ready to take on the week. I walked out to my car and there was tagging on it. Not super excited about that. Took a couple days off that week to deal with everything. Mentally exhausting. That Friday, two teachers proposed that I help take over the AP Art History course work because the permanent faculty was out sick. Sure! I love art history! Oh, they are how far behind? Two weeks? And the test is when? In two weeks? Oh. And I need to prepare a review session? Pre-historic to Proto-Renaissance? Oh. Yeah I can do that. What was I thinking? I spent the entire weekend preparing. It is not that I didn't enjoy it, because, truthfully, I did, it was just exhausting. Tuesday was game day and I was A-MAZING! Those kids had no idea what hit them. That was a good day. However, the day before, Monday, was not a good day. My first class of the day, Block 3, pretty mellow. It can get loud some times but all in all, the kids are good....that is until two girls start throwing punches right behind me. So what do I do? I break up the fight, of course. That may not have been the best idea (I took some punches) but what was I going to do? Let them duke it out? No. Hair was pulled out. Earrings were discarded. Parts of my body were a little sore after but I got some high-fives from a couple students. Plus my Block 5 (which is after lunch) heard all about it and they were excited to see me to hear all of the details!
Back to art history: I am really enjoying getting into it and teaching the students why I love the subject. The kids are great and very thankful the extra work that I am putting in. I think they are finally figuring out that I know what I am talking about.
One more week of school at the University - maybe five more weeks at the high school. Can't wait for this all to be over and get paid to do this!


text:
No one is an island. The community where you live, the food you eat, and the people you know are all part of a global chain of connections. Over the past 10,000 years, humans have transformed the planet - yet the planet has also influenced human life in myriad ways. In these 24 eye-opening lectures, take an interdisciplinary voyage across time and around the world to consider the dual nature of our relationship with "place".
With insights drawn from ecology, anthropology, economics, geopolitics, and more, Professor Robbins reveals the underlying structures that explain why the world is the way it is. Understanding global trends and connections - from environmental changes such as deforestation to the way money and labor slosh around the globe - will give you new insights into the story of human civilization and current events.
One key theme of this course is that "place" is a construct. People make (and constantly re-make) places in response to myriad circumstances, ranging from economic conditions to changes in the ecology around them. Indeed, humans have taken over the Earth so completely that some geologists now refer to our era as the Anthropocene - the "human era".
While it is tempting to despair over humanity's takeover of the planet, you see how the picture is surprisingly complex, and that there is reason for optimism. Much of the human impact on the Earth, from deforestation to rapid urbanization, is not an inexorable march of destruction without any means of revitalization.
In addition to the study of the environment, Professor Robbins examines the wide-ranging implications of a world economy. You'll explore the wellspring of culture and delve into the thorny issues of geography, ethnicity, and statehood. When you complete this course, you'll have all the tools you need to look beyond the headlines and analyze world events in a whole new way.
We've sent an email with your order details. Order ID #:
Listen on the Audible app or these devices.Launch Audible App
-or-Download Free Audible App
To access this title, visit your library in the app or on the desktop website.
Listen on the Audible app or these devices.Launch Audible App
-or-Download Free Audible App
Audible does not currently have the rights to sell this title in your country.
Please consider another book.Continue Browsing
Please add a payment method to continue.Add a Payment Method
Please edit your payment details or add a new card.
If the problem persists, contact customer service at (888) 283-5051Review My Payment Method
If the problem persists, contact customer service at (888) 283-5051
Please add your billing address to continue.Add My Billing Address
Please select a default credit card to continue.Select Credit Card
It looks like you've already used the specified payment method for a free trial.
Please contact customer service if you think we have made a mistake. (888) 283-5051Start Your $14.95 Membership
If the problem persists, contact customer service at (888) 283-5051
If the problem persists, contact customer service at (888) 283-5051
Really enjoyable
This is a great series of lectures. I'm only about lecture eight (of 24) but I look forward to my commute just so I can listen-in. The topics are engaging, the delivery is flawless and I really enjoy it so far.
This guy really knows his stuff. He has completed on-the-ground research in India and has great ways of relating the concepts to actually situations.
- M. Gann
- Corey


text:
Bayley, a ten year old student at a French Immersion School in Toronto who was a pen pal with a student in Liboré, was so moved by the plight of children in Niger, she raised enough money to purchase 40 backpacks to send over to Liboré. The children in Niger sent back photos saying "Thank you Bayley" on the blackboard behind them and holding up their new bags with huge smiles. Bayley then decided to approach her Karate School to raise money for Soccer T-shirts for the children. Her father's company and the Karate school each contributed and the Printer donated part of his costs and some additional soccer uniforms. 100 T-shirts were printed with P4K logos and sent to Niger, and months later the first Pencils for Kids Cup Soccer Tournament was held. It was incredibly moving to see the children in their brightly coloured T-shirts play for the first time. One ten year old girl made such a difference in the lives of so many.
To view photos of the school bag donations, click here.
To view photos of the soccer uniform donations, click here.


text:
The essential book of lighting for professional designers, now updated and revised
Providing the fundamental information new designers need to succeed in a concise, highly visual format, the Second Edition of Lighting Design Basics presents realistic goals that can be used as a guide to create simple yet impressive lighting designs and when collaborating with professional designers on more complex projects.
Drawing on real-world case studies— from kitchens to doctors' offices—the book is packed with attractive, helpful illustrations, making it an invaluable resource for students, as well as interior designers and architects studying for professional licensing exams.
Authored by leading lighting designers with decades of experience Offers straightforward coverage of lighting concepts and techniques Contains design scenarios for more than twenty different types of spaces
Lighting is a basic, yet difficult-to-master element of interior design. Lightning Design Basics changes that, putting the power to create in the hands of the designer.


text:
Bangalore, Karnataka India (PressExposure) November 02, 2011 -- Eka Software, a leading provider of Commodity Trade and Risk Management (CTRM) software, announced today that GrainCorp Limited, one of Australia's largest stock exchange listed agribusinesses has selected Eka for their grain marketing, execution and risk management software.
GrainCorp, which is growing its domestic and international grain marketing business and focused on continuous improvement, require a new CTRM system enabling GrainCorp to build capacity for growth.
For their newly established marketing operations in Europe, GrainCorp will be able to leverage Eka's highly regarded and well-established software for international trading, covering trading, positions, MtM, P&L, execution, exposures, risk, settlement and reporting. For GrainCorp's core origination and grain marketing business, Eka will be replacing multiple legacy systems for pool pricing, grower contracts and grower payments. The system GrainCorp will adopt has already been successfully deployed for other customers in Australia.
According to GrainCorp's Sam Tainsh, General Manager Marketing, "In order to meet our growth targets it is essential that we deploy a system which is fit for purpose, easy to use and flexible. Our challenge was to find the right product platform and partner for the next phase of our growth. We were not only impressed by the EKA product, but also by their people. They demonstrated an impressive depth of knowledge of the grain business and a willingness to work with us to meet our objectives."
Announcing the deal, Manav Garg, CEO & Founder Eka Software Solutions said, "Winning an account as prestigious as GrainCorp is a glowing testimony of our strategy to provide a platform with deep functionality for end-to-end commodity supply chain and risk management. We look forward to working closely with the GrainCorp team to further enhance our product."


text:
Sign In
Fan Fic
CBM Index
Fan Fic
Teletubbies as The Main Villains in The Justice League Movie!?
You know for every comic book film being made there is a hidden villain, and these villains have the biggest agenda and the biggest message to say towards the film. Here, as the title suggest it's only a possibility I care to explore which could become reality.
Filed Under: "
Fan Fic
Hello everyone. Yes as fans we silently anticipate the great upcoming films within the comic book genre. Especially a long waited film called Justice League. Now that we have Man of Steel 2 being the main introduction before Justice League, it's a great speculation to see as why would these heroes come together? Could it be for the cause to stop one of their greatest known villain or villains from the comic books? Or could it be to potentially save the minds of many people being tormented by a certain group of colored fiends from outer space? That's right everyone, those Teletubbies don't screw around with anyone! How can that cute and charming race of alien beings be dangerous and deadly? Well find out more as we divulge into this possible plot.
"So Superman is flying around Earth when he spots a UFO crashing into Antarctica. He calls up Batman and is like, "Yo dawg we got sum trouble!". Then Batman flies to Antarctica cause he now suddenly has super powers and meets Superman there. So they go to the UFO and the ship opens while some purple gas streams out. Then out pops the Teletubbies. Then the Teletubbies run up to them with open arms. Batman is all like, "Awww they wanna hug us!". BUT THEY ARE WRONG! Bam, the Teletubbies clap their hands and sends both Superman and Batman flying backwards across the universe and back on Earth. Then they disappear out of nowhere and teleport to Gotham city to cause some trouble. Then Robin is captured by the Teletubbies and one of the Teletubbies wears his skin so they can start their master plan by taking over the Batcave. Then Green Lantern and The Flash kiss and they show up trying to beat off the Teletubbies in a fight and they loose. Wonder Woman looses in a fight against the Teletubbies! All of em Justice League loose in the fight. Then suddenly this kid shows up and hugs all the Teletubbies and their UFO suddenly appears in the sky. The Teletubbies take the kid and fly off into space. So Batman doesn't care at all and the end." - "May not be actual story"
These Teletubbies are scary aliens, yes they definitely are. Having all of the Justice League loose against these warm creatures shows a sense of humanity towards Earth and there kindness to warm fuzzy creatures like Teletubbies. That is why WB would choose the Teletubbies to be the villains. There is a hidden kindness in them you expect but not a sudden urge of violent actions. Same for Superman's own morals which cross merge between his non killing rule. The Teletubbies would convey those morals in a better sense that people can understand. Another thing that will benefit them is the bigger box office numbers. Make the film Rated G and now you have so much people going to watch than Man of Steel. This is what Man of Steel was missing to make it perfect. This is what DC needs. Forget about their silly villains in the comics it's time revive the popular success of Teletubbies once again! Oh and the Smiling Sun from Teletubbies teams up with Superman as sort of his power energy guidance thing that follows him you know the thing how Superman get's powers from the sun right?
Please comment below with your thoughts and opinions on this subject matter. Have a great day!
: ComicBookMovie.com is protected under the DMCA (Digital Millenium Copyright Act) and...
: ComicBookMovie.com is protected from liability under the DMCA (Digital Millenium Copyright Act) and "Safe Harbor" provisions. This post was submitted by a volunteer contributor who has agreed to our
Code of Conduct
. CBM will disable users who knowingly commit plagiarism, piracy, trademark or copyright infringement. Please
contact us
for expeditious removal of copyrighted/trademarked content. Learn more about our copyright and trademark policies
Related Headlines
Latest Headlines
Comments (39)
From The Web
Top Headlines
The Main Characters Of JUSTICE LEAGUE Ranked From Least To Most Memorable
New Behind-The-Scenes Look At
From The JUSTICE LEAGUE Post-Credits Scene Emerges
JUSTICE LEAGUE Cinematographer Fabian Wagner Would Also Like A Director's Cut Released
JUSTICE LEAGUE: Superman FINALLY Joins The Team On These Alex Ross Inspired Posters And Banner
Visit Our Other Sites!
ComicBookMovie.com Home
CBM Index
Site Map
Terms Of Use
Advertise With Us
Copyright Policies
Trademark Policies
© 2003-2017 Best Little Sites, LLC.
is a registered trademark and has been officially registered with the United States Patent and Trademark Office (USPTO). All logos and images used on this website are registered trademarks of their respective companies. All Rights Reserved. Some of the content presented on our sites has been provided by fans, other unofficial websites or online news sources, and is the sole responsibility of the source from which it was obtained. Best Little Sites is not liable for inaccuracies, errors, or omissions found herein. For removal of copyrighted images, trademarks, or other issues,
Contact Us


text:
Available to Pennsylvania, Maryland, Washington D.C., and Boston Area Residents Only
Avoid the costly expense of a plumbing nightmare! We at Sila are here to help. Our certified Technicians can handle all your plumbing needs and SAVE you some money.
Baltimore and Washington D.C. area Residents Sila is now your full-service heating, cooling, and PLUMBING experts.
Don't flush your money down the drain…
Call Sila today for 1 HOUR of PLUMBING service for only $99.
Schedule Your Plumbing Service Today!


text:
Agitate, America!: ALEC, Stand Your Ground and Trayvon
By Nancy Churchill
A Progressive Visionary
Regardless what is said about the Trayvon Martin case, it's clear no law protected Trayvon from the stalker who shot him. And thanks to George Zimmerman, Trayvon was unable to tell his side of the story at Zimmerman's trial. But even by Zimmerman's own account, if anyone had grounds to invoke the "Stand Your Ground" law that night, it was Trayvon Martin.
But if his death has triggered one of those historical watershed moments that jolts people into action to reclaim our democracy, as it appears to have, then perhaps young Trayvon did not die in vain.
The now-infamous "Stand Your Ground" law is not unique to Florida. At least 21 states have passed similar laws over the past several years, and in nine of these the language is virtually identical to Florida's law. This is because they originated from the same source.
This law is only one of thousands of laws cast like a web across the country by the secretive American Legislative Exchange Council, or ALEC. Through its members — state legislators and corporate executives — it has been hijacking state governments since 1972, picking off legislatures one state at a time with "model" legislation designed to favor its corporate members.
Aided and abetted by the corporate members who will benefit, it drafts up to 1,000 "model" laws each year — on civil justice, commerce, communications, education, energy, health, tax and fiscal policy, and international relations — of which around 200 are passed virtually verbatim in numerous statehouses.
The worst part is that, as a private entity, neither ALEC nor its legislator members are obliged to provide constituents, who must live with these laws once they are signed into law, with any draft or even knowledge of them.
The secretive nature of this process is necessary to protect the perpetrators because these laws are clearly not intended to provide citizens with their constitutional rights. Quite the opposite. "Model" so-called "laws" like Stand Your Ground that are so prevalent across states now — that deprived Trayvon of his constitutional right of protection from his stalker — are often passed in the dead of night with no discussion.
How can this be constitutional?
But despite itself, ALEC has been exposed, in no small part because Trayvon's death laid bare Florida's Stand Your Ground law. Visit http://www.alecexposed.org/wiki/ALEC_Exposed to learn, among other things, "how ALEC bills would privatize public education, crush teachers' unions, and push American universities to the right" making "education a private commodity rather than a public good."
Or "how ALEC bills … disenfranchise Americans and give corporations even more power to use their vast financial resources to influence elections in our democracy."
"Through ALEC," it says, "corporations have both a VOICE and a VOTE affecting your voting rights and elections through these model bills. Do you?"
Now you can. Start by joining a protest, organized by ALEC Exposed, of ALEC's 40th annual meeting at the Palmer House in Chicago at noon, Thursday, Aug. 8 (https://www.facebook.com/events/398759776900781).
Nancy Churchill was raised in the D.R.C. (Congo), raced stock cars on short dirt tracks for 25 years, and is a proud, lifelong member of "We, the People." She lives in Oregon, Ill.
From the July 24-30, 2013, issue


text:
Now Hiring!!
Camp Monroe Staff Application!!
Deadline: April 1, 2017
We're looking outstanding, dedicated, hard-working, Lord-loving college-aged people to work as our summer resident staff for 2017!
Our summer staff will serve as Christian leaders and role models dedicated to ensure each camper has the most meaningful experience possible.
Summer staff are required to complete the full staff training at the beginning of the summer. Our 2017 summer will begin on May 30, 2017 at 10:00am. Staff will have weekends off starting on Fridays around 2:00pm and will be expected to promptly return on Sunday at 1:00pm. Staff will be given a week long break over the 4th of July holiday to rest and re-energize. After a restful week, we will return until our last day of Summer Camp that will be Friday, August 4, 2017.
Staff is filled on a rolling basis so send your application in as soon as possible to receive consideration.
Monroe Camp and Retreat Center Inc. is an equal opportunity employer. Some camp positions have minimum qualifications on physical and emotional abilities, gender and
age limits, and/or religious traditions. Some positions also require minimum certifications regardless of skill level. All applicants are subject to a background check.


text:
The Southern Grants Forum 2017 will be held in Atlanta, Georgia, from April 18 through 20, at the Sheraton Atlanta Hotel.
Special conference rates starting at the per diem of $148 per night are available to Southern Grants Forum attendees. This rate will be offered (subject to availability) from April 15 through 23. The cut-off date for making reservations is March 28, 2017. However, we encourage you to make your reservations early as the room block is limited.
Reservations may be made on-line by clicking on this link to the Southern Grants Forum hotel reservations page OR by copying and pasting the following link into a web browser: https://www.starwoodmeeting.com/Book/SouthernGrantsForum2017. Reservations may also be made by telephone by calling the Sheraton Atlanta Hotel at 1-404-659-6500. If making reservations by telephone, please ask for the "Southern Grants Forum" group rate to receive the discounted conference room rate.
Reservations should be made directly with the hotel (either on-line or by telephone). Conference registration does not include lodging. All attendees are responsible for making their own travel arrangements.
Our conference hotel is conveniently located in the heart of Atlanta with easy access to Hartsfield-Jackson International Airport and to interstates I-20, I-75, and I-85. The Sheraton Atlanta Hotel is also near Atlanta's major attractions, including the Georgia Aquarium; Centennial Olympic Park; Underground Atlanta; World of Coca-Cola; the Martin Luther King, Jr., National Historic Center; and Philips Arena. Public transportation is easily accessible as well.
Sheraton Atlanta Hotel
165 Courtland Street, NE
Atlanta, Georgia 30303
Telephone: 1-404-659-6500
Facsimile: 1-404-524-1259


text:
Get 5% on 10000 and above
success 100%
This offer has expired.
Click to copy & open site
Coupon Details
Get 5% Flat off on BlueStone
1 – The coupon is valid only for diamond products.
2 – Not valid on gold coins, Solitaire or plain gold Jewellery
3 – The coupon is valid on over & above existing discount


text:
James G. Peters, 84, of Brookline, court officer
James G. Peters of Brookline, formerly of the South End, a court officer, died Thursday. He was 84.
Mr. Peters was a protopsaltis emeritus for St. George Antiochian Orthodox Church in West Roxbury.
Husband of the late Sadie A. (Kenaan), Mr. Peters is survived by a son, Carleton J.G. of Brookline; a daughter, Ramona J. Locke of Brookline; four grandchildren; two great-grandchildren; and many nieces, nephews, grandnieces and grandnephews.
|The article you requested has been archived
- More On:
- James G. Peters


text:
Smartphone and a DSLR can be a great combination when you use MaxStone. MaxStone is a Bluetooth gadget, which controls DSLR via Smartphone. It is a remote shutter cum Camera locator.
MaxStone a small gadget that can be attached with your DSLR strap. It connects with your iPhone built in IR blaster and you can remotely control the Camera's shutter from your iPhone. It also supports video start/stop recording on some models of camera.
A wireless remote that let you control your DSLR camera through your iPhone (smartphone) + much more! Let's iPhone your Camera!
The best part of this tiny gadget is it also works as a device locator. Its built-in Bluetooth proximity alarm sensor locates the device when you move away from it. It instantly send alarm to your iPhone with showing distance.
The MaxStone was created by Will E, Lia Zhang, Shawn Han and Will Griffith. They are currently funding in KickStarter project with a goal of $50,000. They already successfully funded and raised $75,082 and 46 days remaining.


text:
New American Girl Kirsten Birthday Dress Outfit NIB Retired Not doll & boots
Sold for:
Start Free Trial
or Sign In to see what it's worth.
- Sold Date:
- Source: eBay
American Girl
Kirsten Birthday OutfitYou are bidding on a New in the box American Girl Kirsten Birthday outfit for dolls.
(dolls are not included).
They have never been removed from their original box. �
SOLD OUT!! SOLD OUT!!This set has been retired and will be hard to find. Apron Dress & Daisy Wreath
For Kirsten's first American birthday she wore a summery� dress� covered with a crisp� white apron.
� Beige-and-white-striped socks
A� daisy� wreath� for Kirsten's long blond hair.
(Includes� dress,apron,socks,and� wreath)
� DOLL and BOOTS shown in the photo are NOT included
This item has never been out of the box, I purchased item myself directly from American Girl.Buyer to pay $5.95 for shipping. I accept payment from Paypal and other payments if asked. I will ship this right out as soon as payment is received!! Please be kind and only bid if you will follow through with auction. Thank you, Debbie....


text:
CSR Middle East, CSR dedicated platform with 3.280 corporate members in the Middle East.
One stop source for Corporate Social Responsibility news, events, jobs, reports, directories, etc.
We believe the importance of CSR, join us today!
Ithmaar Bank, a Bahrain-based Islamic retail bank, was singled out among the world's Islamic banks for a prestigious international award in recognition of its corporate social responsibility and financial disclosure.The award was presented at the World Islamic Banking Conference (WIBC), which was recently held in Bahrain in strategic partnership with the Central Bank of Bahrain (CBB).The event, w…
© 2017 Created by Dr. Fatih Mehmet Gul.
Powered by
Badges |
Report an Issue |
Terms of Service
Please check your browser settings or contact your system administrator.


text:
Welcome to SPN
Register and Join the most happening forum of Sikh community & intellectuals from around the world.Sign Up Now!
Abdul Sattar Edhi . A Ray Of Hope In Midst Of Islamism Religious Fanaticism
Discussion in 'Hard Talk' started by Seeker2013, Jul 3, 2016.
XenPorta 2 PRO © Jason Axelrod from 8WAYRUN.COM


text:
With Lytton John Musselman and Peter Schafran
Aperitifs and bitters stimulate appetite before a meal while cordials are traditional after-dinner drinks. Learn how unique and delicious spirits can be prepared from native plants using only one or two ingredients and no specialized equipment. Then join us on the terrace to sample and evaluate a selection of fifteen hand-crafted beverages. Celebrate your next special occasion with your own signature cocktail! (Ages 21 and over).
$35Register Now


text:
Contact Info / Websites
- itspudding8D
All 26 movie Reviews
Ryu vs Akuma
Rated 3.5 / 5 stars
pretty ok to me i like it keep at it
Thanks, glad you enjoyed it.
Africa Dudes
Rated 5 / 5 stars
tht was funny as shit XD but i didnt know when it would end longest thing ive wever watched on NG
Mortal Kombat FAILtality
Rated 5 / 5 stars
i see some ones a fan a valve the scout from TF2 fits perfectly wit striker XD loved it i think my favorite one was scorpion and shame on thee who raates this 8 or lower
Ham Hams Final Hour
Rated 2 / 5 stars
i only laughed for like maybe 2 seconds and yeah.......tryed to hard to make this funny ......'___';
VG Exiles - Episode 2
Rated 5 / 5 stars
that was so beast u make me wanna try and make sumthin like this not dissing proxcide but i think this is better btw when is Exiles Ep 3 or the next part to this series coming out im so excited to see what happens thanks ^o^ nice choice of music whats the name of it
MK vs. SF -VG Exiles Ep.0
Rated 5 / 5 stars
:O omg awesome
oh and Scroler this is awesome if u aint got nothin good to say keep ur comment to yourself ya dam troll and R166S awesome what was ur music choice?
"Customized Genotype" by ETNA.
They have since changed their name to BREACH THE VOID.
Awesome Center Redux
Rated 5 / 5 stars
omg dude every time i think of it ROTFL!
DOCTOR! we need help defusing this attom bomb...OPEN THAT SHIT UP!!!! LMAO
Ultimate Skate Video 2:SE
Rated 4 / 5 stars
its cool but thats rodney mullen bassically i can tell ive seen mostly all his vids and thats from his vid
Madness vs Thingthing
Rated 2.5 / 5 stars
sorry not all what i thought
madness and thing thing dont look like that idk if that even thing thing plus hes not human but ok on the fihting wish they could make it the right way in there original look but i say give it nothre try
Hankman: Madness Asylum
Rated 5 / 5 stars
nice choice of song breaking benjimin rules goes good with madness combat drifts u rule :D


text:
Create a cozy countryside effect in your kitchen or dining room with this set of traditional bar stools. They all feature nylon chair glides and saddle shaped seating. The turned legs add a splendid visual appeal that would look great in any home. The barstools are made out of select hardwoods and oak veneers for a mission flair. Have a drink with a friend or watch the game while relaxing on one of these great bar stools.
Browse other items in the Nostalgia collection from Furniture and ApplianceMart in the Stevens Point, Rhinelander, Wausau, Green Bay, Wisconsin Rapids, Marshfield, East and West Madison, Wisconsin area.
Nothing on this page may be copied or reproduced without explicit permission.


text:
FU MANCHU are one of hard rock's most celebrated names that also helped give rise to a celebrated style of heavy music tagged "stoner rock" alongside peers such as Kyuss, Monster Magnet and Sleep, Since its inception, the quartet has built itself a fanatical army of loyal enthusiasts all drawn to the group's ridiculously catchy, unpretentious music, guitar-driven sound and carefree lyrics centered on "old muscle cars, choppers, vans, skateboarding and science fiction, Rolling Stone probably said it best when it described the band as "a transcendent distillation of Seventies rock heaviness and Eighties punk aggression", Their 11th album Signs of Infinite Power was Recorded at Maple Studios in Santa Ana, California by the band and producer Sergio Chavez (Motorhead) and mixed by Andrew Alekel (Foo Fighters) delivers monstrous doses of the group's punk energy, hard rock drive and psychedelic crunch in spades.
Cat No: 9979502
Barcode: 5051099795020
Packaging: CD Regular
Be The First To Review This Product!
Help other Nerve Gas users shop smarter by writing reviews for products you have purchased.


text:
the aggregation of policies and practices in employment and other areas that do not discriminate against persons on the basis of race, color, age, sex, national origin, religion, or mental or physical disability.
The goal of giving all persons an equal chance to an education and employment, and to protect their civil rights, regardless of their race, religious beliefs, or gender. In the United States, various minority groups have been fighting for equal opportunity over the last 150 years. (See affirmative action, civil rights movement, equal protection of the laws, National Association for the Advancement of Colored People, National Organization for Women, segregation, sexism, suffragist, and women's movement.)
Tagged: e
Read Also:
- Equal pay
noun 1. the right of a man or woman to receive the same pay as a person of the opposite sex doing the same or similar work for the same or a similar employer
- Equal protection of the laws
A phrase in the Fourteenth Amendment to the United States Constitution requiring that states guarantee the same rights, privileges, and protections to all citizens. This doctrine reinforces that of due process of law and prevents states from passing or enforcing laws that arbitrarily discriminate against anyone.
- Equal-rights-amendment
noun 1. (def 3). Equal Rights Amendment (ERA) A twice-proposed but never ratified amendment to the Constitution that would prohibit denial or abridgement of rights on the basis of sex. First proposed in 1923, the amendment was passed by Congress in 1972 but failed ratification by the requisite number of states. It was a major […]
- Equals
[ee-kwuh l] /ˈi kwəl/ adjective 1. as great as; the same as (often followed by to or with): The velocity of sound is not equal to that of light. 2. like or alike in quantity, degree, value, etc.; of the same rank, ability, merit, etc.: two students of equal brilliance. 3. evenly proportioned or balanced: […]


text:
Justin Bryant2 Comments
December 31, 2016
In this video, I'll show you 10 internet marketing strategies that get TechCrunch massive amounts of traffic on their website. This is a brand that gets millions of views per year covering the latest news from tech startups.
TechCrunch also happens to have millions of followers on social media. I'll show you 10 of the top online marketing strategies they are using to get so much traffic, so you can learn from and apply them to your own business.
Enjoy the video and let me know what you think in the comments below!
I'm an entrepreneur, fitness freak, artist, car enthusiast, sports fan and self improvement addict. My goal is to help people be their best and create incredible businesses that change the world.
James C Moore
Hey Justin,
Great video. It allowed me to receive a better understanding of what resources are out there for me to use. I would love for you to direct me to an implementation plan that you used to get to where you are today. It would really help me out.
Thank you,
James Moore
Justin Bryant
Hey James,
As far as where to start to get to be fairly successful with an internet-based business, I would say start with this video: https://www.youtube.com/watch?v=3gANZJscl_s
I had to figure everything out the hard way, so you don't want to do exactly what I did, but that video should help you get started on the main principles and process for getting to a good level.
Hope that helps!
* Denotes Required Field
How To Brand Yourself As An Expert In Your Field In 10 Steps
25 Instagram Marketing Tips
Viral Blogging | 17 Sites To Help Posts Go Viral
Tony Robbins Quotes – His 75 Most Motivational Lines
10 Habits Of Millionaires That Will Make You Successful
Copyright © 2017 · Bryant Business Assets, LLC · All Rights Reserved
We take good care of our readers. As thanks, we'll send you our course "Turn Any Business Into An Online Empire" FREE + secret gift (Valued at $315)! Where should we send it?
We value your privacy and would never spam you.