text:
|Publication number
|Publication type
|Application number
|Publication date
|5 Jan 1988
|Filing date
|19 Nov 1984
|Priority date
|19 Nov 1984
|Fee status
|Publication number
|J. Craig Barnett
|Original Assignee
|Texas Tech University Health Sciences Center
|Export Citation
|BiBTeX, EndNote, RefMan
|Patent Citations (11), Referenced by (24), Classifications (11), Legal Events (4)
|External Links: USPTO, USPTO Assignment, Espacenet
This invention relates to an apparatus for performing tests to measure the amount of glucose in the blood with improved accuracy, repeatability and reliability.
It is well known that measurements of blood glucose can be made by placing a drop of blood on a prepared reagent pad, allowing the blood to react with the materials on the pad for a fixed period of time, washing and then removing excess water from the pad, and then evaluating the color of the reacted area by comparison with a standard. The enzyme glucose oxidase catalyzes the oxidation of glucose in blood by oxygen in the atmosphere, producing gluconic acid and hydrogen peroxide. In the presence of peroxidase, chromogens in the reduced form are oxidized by the hydrogen peroxide and produce colors which range from gray to blue-purple. To avoid the inherent problems associated with visual comparison with a chart, a reflectometer using a light source, a photocell and electronic color evaluation is usable. One device suitable for this purpose is the blood glucose meter marketed by the Ames Division, Miles Laboratories, Inc., Elkhart, Ind.
While the theory is sound and while tests of this type can be performed to give accurate results, there are some serious practical problems in that the various steps must be performed with considerable precision in order for the results to be reliable. Specifically, the reaction time, i.e., the duration of the interval during which the blood is allowed to react with the materials in the pad, is quite critical.
Also, in order for the test results to be comparable, the washing must be performed in the same way each time and, after washing, the removal of excess water, often accomplished by blotting, must be done in a consistent fashion. If these steps are not done the same way each time, the blood samples from a single patient can be evaluated to indicate either a significant change in glucose level when none has actually occurred, or the reverse. While the experienced, skilled laboratory technician can obtain good results consistently, an inexperienced one may not. Of even more importance, a person attempting to perform the test at home may obtain widely varying measurements, resulting in over- or under-medication. It is important for some patients, particularly diabetics, to be able to conduct such tests on their own and the glucose meter mentioned above is sold for that purpose. However, unless the instructions are followed with precise consistency, it has been found that 30% or more of the measurements can be in error.
An objective of the present invention is to provide an apparatus which can perform blood glucose testing in a uniformly repeatable fashion with accurately and consistently performed and timed steps.
A further objective is to provide a testing device which is simple to use and which can be used by minimally trained individuals such as a patient doing a self-test.
Another objective is to provide a device which is not overly complicated and which can thus be produced at a reasonable price so as to be readily obtainable by individuals and small laboratories.
Briefly described, the invention comprises an apparatus for performing a test to determine the glucose level in a sample of blood placed on a reagent pad comprising the combination of means defining a receiving station, a wash station, a watering station and a measuring station in spaced relationship from each other and carrier means for holding the reagent pad, the carrier means being movable to transport the pad to each of the stations in sequence. Drive means is provided for moving the carrier means to transport the pad the stations and to hold the pad at those stations for preselected intervals of time. The wash station includes means for washing the pad when the carrier is moved to the wash station. The de-watering station includes means for removing superficial water which remains after the washing from the pad and the measuring station includes means for producing a signal representative of the color characteristics of the pad when the pad is presented to the measuring station. Finally, the apparatus includes means for receiving the signal and for producing a display representative of the glucose level in the blood sample.
In order that the manner in which the advantages of the invention are attained can be understood in detail, a particularly advantageous embodiment thereof will be described with reference to the accompanying drawings, which form a part of this specification, and wherein:
FIG. 1 is a perspective view, partly cut away, of an apparatus in accordance with the invention;
FIG. 2 is a plan view, in partial section, of the apparatus of FIG. 1;
FIG. 3 is a side elevation, in partial section, of the apparatus of FIGS. 1 and 2:
FIG. 4 is an end elevation of the apparatus of FIGS. 1-3;
FIG. 5 is an enlarged partial side elevation, partially in section, showning the mounting arrangement for a rotatable carrier usuable in the apparatus of FIGS. 1-4;
FIG. 6 is a fragmentary top plan view of a portion of the carrier of FIG. 5 taken along line 6--6;
FIG. 7 is an end elevation, partly in section, along line 7--7 of FIG. 5;
FIG. 8 is an enlarged partial side elevation of the front portion of the carrier structure of FIG. 5;
FIG. 9 is a top plan view of the structure of FIG. 8;
FIG. 10 is an end elevation of the structure of FIGS. 8 and 9;
FIG. 11 is a partial end elevation, partly in section, of a washing cup structure usable in the apparatus of FIGS. 1-4;
FIG. 12 is a top plan view of the portion of the apparatus including the washing structure of FIG. 11;
FIG. 13 is a partial side elevation along line 13--13 of the washing cup structure of FIG. 11;
FIG. 14 is an enlarged end elevation, partly in section along line 14--14 of FIG. 15, of a de-watering apparatus usable in the apparatus of FIGS. 1-4;
FIG. 15 is a side elevation of the de-watering apparatus of FIG. 14;
FIG. 16 is a perspective view of the exterior of an apparatus in accordance with the invention in a charging base;
FIG. 17 is a schematic diagram, partly in block form, of a control apparatus usable in conjunction with the present invention; and
FIGS. 18 and 19, taken together, show a functional block diagram of the sequence of steps usable in a control system for the apparatus of the invention.
Referring first to FIGS. 1-4, a general description of the apparatus will be provided. The embodiment to be described is in the form of a portable apparatus usable to perform the necessary test under a variety of circumstances. As such, it is relatively small and is contained in a generally rectangular housing, various portions of which are omitted from the drawings so that the interior components can be more easily seen.
Within the testing apparatus, indicated generally at 20, is a generally cylindrical body 22 which is rotatable about its central axis in a manner to be described and which functions as a carrier for the reagent pad by which the test is performed. As seen in FIG. 2, carrier 22 is an elongated body one end of which protrudes through an opening 23 in and wall 24 of the housing. In the position shown in FIGS. 1-4, the rotatable carrier supports an axially extending strip holder 26 which can be caused to move axially with respect to carrier 22 for the purposes of receiving a test strip 27, withdrawing that strip into the apparatus during the test performance and then extending the strip for subsequent removal. The test strip 27 carrier a reagent pad 28 to which the drop of blood is applied for performing the test.
Although other test strips can be employed, the present apparatus is designed to use an existing test strip which is sold under the trademark DEXTROSTIX by Ames Division, Miles Laboratories, Inc., Elkhart, Ind. The DEXTROSTIX strips are relatively thin, flexible plastic strips having a width of about 3/16 inches and a length of about 3.25 inches. At one end of each such strip is a reagent pad having a width equal to that of the strip and a length of approximately 13/32 inches. The reagent pad is impregnated with the necessary reagent ingredients to accomplish the oxidation described above and the activity of the chromogens which produce a calibrated color change which is a function of glucose level in the sample supplied to the reagent pad. These specific pads are provided with 1.0 IU glucose oxidase; 1.14 IU peroxidase; 30 μg 3,3'-dimethyl, - 4,4'-diaminobiphenyl dihydrochloride; 20 μg 2,7'-diaminofluorene dihydrochloride; 50 μg 4,4'-diaminobiphenyldihydrochloride; and 96% w/v nonreactive ingredients.
As seen in FIGS. 1, 2 and 3, with holder 26 in the retracted position, pad 28 is in the position shown in FIG. 2 and the end of the holder is flush with the end of carrier 22 and the outer surface of wall 24.
Also within the housing is a wash cup 30, a de-watering device indicated generally at 32, a water storage tank 34 for containing a supply of wash water, a reservoir 36 to receive used wash water, an air tank 38 which contains pressurized air to control the washing action, and a measuring device 40 which contains a light source and photocell to accomplish the reflectance test. The housing also contains a metering pump 42 and a valve 44 for delivering a measured amount of water to a discharge chamber 46. Additionally, a pressure regulator and valve mechanism 45 controls the flow of pressurized air to discharge chamber 46 to control the washing action.
The inner end of carrier 22 is provided with a toothed ring forming a gear 50 which engages a gear 52. Gear 52 is mounted on the output shaft 54 of a drive motor 56 which can also contain reduction gearing, if desired.
As carrier 22 rotates, it is capable of carrying holder 26 with its strip 27 and pad 28 counterclockwise to four different stations which are easily recognized in FIG. 4. The first station is the receiving station at which strip 27 exists in FIG. 2 and, as viewed in FIG. 4, is at the upper position corresponding to the 12:00 position on a clock. The second station is at the 9:00 position, 90� counterclockwise removed from the first station, at which the washing of the pad 28 occurs. The third station, at the 6:00 position, is the de-watering station and the fourth position, at the 3:00 location, is the measuring station. The drive motor 56 is energized in such a way that strip 27 and pad 28 remain at each of the stations for a predetermined time as will be described.
The mechanism for receiving and holding strip 27 is more clearly shown in FIGS. 8, 9 and 10 when viewed in conjunction with FIGS. 2 and 3. As seen in these figures, holder 26 is an elongated body having upstanding side walls 58 and 59 extending along a portion of the length of the body, the upper edges of walls 58 and 59 being serrated along most of their lengths except for flat end portion 71. Between these side walls is a flat surface which receives strip 27 with pad 28 disposed near the outer end of the holder. As seen in FIG. 10, carrier 22 is provided with a recess 60 which slidably receives holder 26. In addition, carrier 22 has an elongated bore 68 extending axially away from recess 60 to slidably receive a guide rod 62 which is unitarily formed on and protrudes from the end of holder 26.
Also as seen in FIGS. 8 and 10, a small cavity 47 is formed in the end of carrier 22 adjacent and below holder 26. A metal strip 48 is embedded in carrier 22 and has an end portion which lies on the bottom of cavity 47. A second metal strip 49 is embedded in the polymeric body of carrier 22 and extends parallel with strip 48. The end of strip 49 lies above and spaced from strip 48. Strip 49 is formed from a springy material of a type used in electromagnetic relays, such as phosphor bronze, and both of strips 48 and 49 are provided with electrical contact members at the ends in cavity 47.
At the other end of carrier 22 a circular boss 53 of plastic protrudes through an opening in gear 50, positioning the gear and providing an insulating passage for the other ends of strips 48 and 49, reduced width portions of which protrude beyond boss 53 toward wall 128. Spring contacts 55 and 57 pass through wall 128 and are bent in an L-shape in the direction of counterclockwise movement of the carrier, the bent portions being positioned so that they are contacted by the ends of strips 49 and 48 when the carrier is in the receiving position as shown. Wires 61 connect the spring contacts to a control circuit.
Holder 26 is made of a polymeric material which is reasonably flexible so that when it is in its extended position illustrated in phantom lines in FIG. 8 and when the distal end thereof is pressed downwardly by pressure of a finger against pad 28, the holder bends into a shallow curve. The lower surface of holder 26 thus enters cavity 47 and presses downwardly on strip 49, bending that strip until it makes contact with strip 48. If the carrier is in the receiving position such that the other ends of strips 49 and 48 are in contact with spring contacts 55 and 57, a circuit is completed between wires 61. These wires are connected to the control circuit to provide a start signal upon completion of this circuit, thus initiating the timing sequence as soon as a finger with a sample of blood thereon is pressed onto pad 28.
An elongated spur gear 64 is mounted on a shaft 65 which is supported in journal blocks 66 and 67 on the housing. Shaft 65 is rotatably driven, in either direction, by a small electric motor 69 mounted on tank 36 and coupled to the shaft by an elastic drive belt 70. The teeth of gear 64 engage the serrations along the upper edges of walls 58 and 59 so that when motor 69 is energized in the appropriate direction, the holder 26 is caused to move axially, presenting a portion of the length of the holder beyond end wall 24. The extent of this movement is sufficient, as determined by the length of the serrated portions of walls 58 and 59, to extend the holder so that pad 28 protrudes well beyond end wall 24. The movement is limited by non-serrated portions 71 and movement in the opposite direction is also limited by the abutment of the inner end of holder 26 against the end of recess 60. In either direction, if motor 69 remains energized when one of these limits is reached, band 70 simply acts as a slip clutch. When the holder is in its extended position, the strip and pad can be inserted in the holder so that the end with pad 28 is close to the outer end of the holder and most of the remainder of the strip lies between walls 58 and 59. The inner surfaces of walls 58 and 59 are provided with a plurality of inwardly protruding bumps 63 beneath which the strip is slipped to hold it in place. The holder and carrier 22 are preferably formed from polymeric materials such as nylon or Teflon which have relatively low coefficients of friction.
As seen in FIGS. 4 and 10, a second recess 74 is formed in carrier 22 to receive a second holder 75 similar to holder 26 but lacking serrated side walls such as 58 and 59. The second recess is disposed 90� away from recess 60 in the counterclockwise direction, as viewed in FIG. 4, to receive a manually inserted holder carrying a strip which has no blood sample applied to its reagent pad. This "advance" strip can then act as a standard to be sure that the instrument is properly calibrated.
The arrangement of the washing apparatus is illustrated in more detail in FIGS. 11, 12 and 13. In those figures, carrier 22 is illustrated with holder 26 rotated 90� to the wash position. The wash mechanism includes a wash cup 30 which is a generally rectangular body having an open side with inclined upper and lower edges 87, 88 to conform to the slope of carrier 22 and arcuate side edges 89 and 90 which are curved to also conform to the curvature of carrier 22 on axially opposite sides of pad 28. A back wall 91 of the wash cup is provided with an inlet nozzle 92 having a central opening through which water can be conducted for the purpose of spraying the surface of pad 28. Nozzle 92 is connected to a hose 93 which leads to the outlet of discharge chamber 46. Before washing, a measured amount of water, e.g., about 4 cc., is delivered by a positive displacement pump 42 through valve 44 to chamber 46. When washing is to be accomplished, valve 48 operates to apply air under pressure to tank 46, forcing the water from chamber 46 through tube 93 to wash cup 30 wherein the water is forcibly sprayed in a stream against the pad. At the lower end of back wall 91 is a drain opening 95 which is connected by a hose 96 to tank 36. After the wash water has been expended, continued flow of air under pressure forcibly drains the wash cup.
Cup 30 is supported on an arm 98 which is connected to the movable plunger 99 of a solenoid 100. When energized, solenoid 100 retracts plunger 99 and, with it, arm 98 and wash cup 30 so that rotation of carrier 22 can proceed without any interference between the forward edges of cup 30 and protruding portions of holder 26. When the solenoid is de-energized, a compression coil spring 97 surrounding plunger 99 and acting against an enlargement on arm 98 presses the cup against carrier 22.
It will be observed that tubing 93 is provided with an upwardly extending U-shaped bend to permit movement of cup 30 and also to prevent gravity feed of water from chamber 46 into the wash cup.
A de-watering mechanism is shown in FIGS. 14 and 15, the de-watering technique used in this embodiment of the apparatus being a blotting operation. The blotting mechanism indicated generally at 32 includes two major portions, a solenoid-activated blotting arm 102 which is permanently mounted within the housing of the testing apparatus 20 and a blotting paper cartridge 104 which can be removed from the apparatus and can be either refillable or replaceable. The paper cartridge 104 includes a housing 105 of polymeric material which contains a reel of blotting paper 106. Housing 105 is provided with a chamber to receive the reel of blotting paper, the upper end of the storage chamber being formed into a guide slot 108 through which the paper extends, bridging a gap between slot 108 and a similar inlet slot 109. The blotting paper then continues down the inside of the housing and emerges through a discharge slot 110 at the bottom of housing 105 which is aligned with a slot in the bottom of the housing of apparatus 20. It will be observed that a wall 111 along the discharge side of housing 105 has an inner surface which increases in thickness toward the discharge opening, thereby forming an inwardly and downwardly sloping wall.
The blotting mechanism fixedly mounted within the housing includes a solenoid 112 having a plunger 114 which is pivotally connected to one end of arm 102 and which is surrounded by a compression coil spring 103. Arm 102 is pivotally mounted on a pivot pin 116 which is supported in a mounting block 117 supported on the housing. The other, longer arm of blotting lever 102 is generally T-shaped in cross section, the transverse portion of the T supporting a blotting pad 119 which has an inclined upper surface. Thus, when solenoid 112 is actuated to retract plunger 114, arm 102 pivots in a counterclockwise direction, as viewed in FIG. 15, moving the inclined surface toward pad 28 positioned above it. The inclined upper surface of the blotting pad is thus substantially parallel with the surface of pad 28 when contact is made. The paper 106 from cartridge housing 105 extends across the upper surface of pad 119 and is brought into intimate contact with pad 28 to perform the blotting operation. Pad 119 is preferably made of a relatively soft, foam polymeric material to enhance the blotting operation.
Arm 102 also carries a feed mechanism to advance the blotting paper. This mechanism includes a diagonally extending arm 121 carried by the vertical portion of arm 102, arm 121 ending in a generally vertically extending plate 123 which is provided with a series of protruding points 124 extending toward that portion of the blotting paper leading to the discharge opening. When arm 102 moves upwardly, plate 123 with points 124 also move upwardly, the points being downwardly inclined so that they simply slide along the inner surface of the blotting paper, creating substantially no motion of the paper. Also, points 124 are moving away from the inner surface of wall 111 because of the decrease in thickness thereof in the upward direction. After the blotting is accomplished and solenoid 112 is de-energized, spring 103 causes arm 102 to swing downwardly, permitting points 124 to engage the blotting paper and cause it to move downwardly, extracting a fresh supply from reel 106 with each such motion. Thus, stepwise increments of new blotting paper are presented to the space between pad 119 and reagent pad 28. After a test has been accomplished and holder 26 has been moved away from the de-watering station, solenoid 112 can be energized three or four times to activate the feeding mechanism repetitively, thereby moving a totally new blotting paper supply into position for the next test.
The measuring device 40 at the fourth station need not be described in detail since it is a conventional device which involves illuminating the pad 28, receiving light reflected from the pad and producing an electrical signal representative of the pad color. That signal is coupled by wires, not shown, to an analysis device in the rear portion of the apparatus housing.
A mounting arrangement for carrier 22 is illustrated in FIGS. 5, 6, 7 and 8. An elongated rod 126 is mounted in a transverse wall 128 extending across the interior of the housing. Rod 126 is threaded at one end and held in position by nuts 129. Gear 50, which is attached to the inner end of carrier 22, has a roller bearing 130 centrally mounted therein, the bearing being slidably supported on rod 126. At the other end, carrier 22 has a second roller bearing assembly 132 similarly supported at the distal end of rod 126. An opening through the outer end of body 22 receives a quarter-turn fastener 134 which engages an internally slotted opening in the distal end of rod 126 to keep body 22 on the rod. The fastener is preferably latched with a left-handed movement to prevent removal with normal counterclockwise motion of body 22.
An intermediate wall 76 extends across the interior of the housing of apparatus 20 and has an opening through which air tank 38 extends. Wall 76 also has an opening which receives a ring 77 attached to and surrounding carrier 22, ring 77 having a diameter which is at least as large as the diameter of a circle concentric with carrier 22 and passing around the outer limits of walls 58 and 59. Ring 77 can be made of metal or low friction plastic so as to freely slide in opening 76 as carrier 22 rotates, providing support at the approximate midpoint of carrier 22.
FIG. 5 also illustrates a mechanism for proper rotational positioning of body 22 including four orthogonally disposed reflective regions 138 and an optical sensor 140. Sensor 140 includes a light source and a photocell positioned to project light toward and receive light from, respectively, reflective regions 138. The regions can be simple dots, lines or bar codes, but in any event, reflect light from the source to the photocell within sensor 140 to provide a signal representative of the proper positioning of the body 22 about its rotational axis.
Before discussing the control aspects of this apparatus, the overall operation will be briefly reviewed. A test is initiated by inserting a test strip with a reagent pad into holder 26 when the holder is in its extended position. The test strip must be positioned initially so that pad 28 is outside of the housing and rests on the protruding portion of holder 26. A second strip is inserted into holder 75 with its pad similarly positioned. A sample of blood to perform the test is obtained by puncturing a portion of the body such as the fingertip, using a device such as a MONOLET or AUTOLET puncturing device sold for this purpose. The blood sample is then placed on pad 28 by pressing the punctured portion of the finger downwardly against the pad, causing holder 26 to bend into cavity 47 so that the contacts on strips 48 and 49 are closed. This produces a signal which causes motor 69 to be energized and starts the timing of the reaction. Thus, the strip is immediately slid into the holder until the end of the strip abuts the inner end of recess 60. The timing mechanism retains the holder in this location for an interval of 60 seconds to permit the blood to react with the reagent substances provided on the pad. Near the end of this interval, the "standard" pad is washed and chamber 46 is refilled with water. At the conclusion of the 60-second interval, carrier 22 is rotated 90� so that the pad 28 is presented to the wash station and the wash process is commenced by projecting a stream or spray of water through nozzle 92 and onto the pad, the wash being accomplished for a predetermined interval, for example, one second and using a measured volume of water supplied by pump 42 which can be, for example, 4 cc. Sufficient air pressure from tank 38 is supplied to inject the water and to then flush excessive used wash water through the drain opening and into tank 36. While pad 28 is being washed, the pad on the "standard" strip is blotted by energization of solenoid 112.
Wash cup 30 is then retracted by energizing solenoid 100 and carrier 22 is rotated to the de-watering station at which solenoid 112 is energized to pivot arm 122 so that pad 119 moves upwardly, pressing blotting paper 106 against pad 28 and removing excess water therefrom. Energization can be repeated, advancing the blotting paper and reblotting the pad for a predetermined number of times. It is, however, not necessary to dry the pad; it is simply necessary to remove excess water which would effect the reflectivity of the pad. While pad 28 is at the blotting station, the standard pad is at the measuring station where its reflectivity is measured.
Carrier 22 is then rotated again to convey pad 28 to the measuring station at which a beam of light is employed to illuminate the pad and a photocell is used to receive the light from the pad, producing an electrical signal which has a magnitude proportional to the color of the pad within the range of interest. The reflectometer portion of the apparatus is conventional and will not be described in detail. However, the signal is employed to produce a display of the glucose level as revealed by the color change undergone by the reagent pad. Preferably, the electronics used for processing the reflectometer signal includes one or more memory locations for storing one or more correction factors which can be inserted to correct the signal for the individual patient. This correction factor is needed to correct the glucose level calculation to account for various conditions which can alter the correlation curve and so that the displayed value can be treated as a chemical value.
FIG. 16 shows an overall perspective view of the exterior of an apparatus 20 mounted in a charging base 142 which can be used to recharge batteries housed in unit 20 behind a cover 143. Base 142 can also contain circuitry to monitor functions in unit 20.
Unit 20 has a reduced-size end portion 145 which can act as a handle and which contains the test and control electronics to perform the functions discussed above. The control apparatus is relatively simple and can either be hardwired discrete components or a combination of some hardwired components with a programmed microprocessor, the latter being preferred. The upper face of handle portion 145 includes push-buttons 146, 147 and 148 to turn the unit on, reset the internal logic and to turn the unit off. An LCD type of display is provided to indicate glucose level or other characteristics which can be measured and displayed.
A series of lights are provided as illustrated to indicate conditions of the apparatus including adverse conditions such as inadequate air pressure in tank 38, insufficient water in tank 34 or inadequate power in the batteries to perform a test. A "ready" light 149 which is also a push-button switch illuminates to indicate that the device is in condition to perform a test. Lights labeled "STAND." and "SAMPLE" are used to indicate that the reading being displayed on display 150 at the time when one of those lights is illuminated is a reading of the standard, which should indicate zero glucose level, or of the blood sample.
FIG. 17 shows an overall schematic diagram of the control apparatus including strips 48 and 49 which, when brought together by bending holder 26, produce a signal on wires 61 which is delivered to a pulse shaper 151 which produces a pulse for delivery to micro-processor 153. The batteries indicated generally at 155 are connected to provide voltage to microprocessor 153, to strips 48 and 49 and also to the other components by wires which are not illustrated in FIG. 17.
Water and air tanks 34 and 38 are provided with level and pressure monitors, respectively, 156 and 157 which supply inputs to microprocessor 153. An output of microprocessor 153 is supplied to a bistable device 159, which can be a relay, to energize drive motor 56 to cause rotation of carrier 22. The photoresponsive device 140, as previously described, senses the presence of reflective regions 138 on carrier 22 and provides signals to de-energized bistable device 159 and to provide an "off" signal to microprocessor 153.
The functional aspects of the system and the general outline for programming a microprocessor for performing the necessary functions is shown in FIGS. 18 and 19. Initially, as soon as the power is turned on by depressing switch 146, the air pressure, water level and input voltage are checked and, if these supplies are adequate, the "ready" light is illuminated and the motor 69 is energized to extend strip holder 26 to receive a strip. If any of these is inadequate, a light indicating which is inadequate is illuminated and the routine is ended, preventing the possibility of performing a test with inadequate air, water or power. When the ready light is illuminated and holder 26 is extended, a fresh test strip is inserted into the holder with the pad toward the distal end of the holder, as shown. The user then depresses the ready light switch button which permits the microprocessor to supply voltage to strips 48 and 48. A sample of blood can then be applied to pad 28, depressing sample holder 26 and closing the contacts on strips 48, 49 to produce a start signal. If no start signal is provided, the routine is in a hold status. As soon as the start signal is supplied, the 60 second timer is started, the sample holder 26 is retracted and a shorter timer having an interval of about 50 seconds is started. At the end of the 50 second interval, the wash cup is extended toward carrier 22, the standard pad is washed, tank 46 is refilled, the wash cup is retracted, and a "retracted" state is flagged. At the expiration of the 60 second interval, assuming that a wash cup retracted flag has been set, the carrier is rotated through 90 degrees.
Continuing onto FIG. 19, after rotation of carrier 22, the wash cup is extended, pad 28 is washed, the wash cup is retracted and the "retracted" flag is set. Meanwhile, blot solenoid 112 is energized to blot the standard pad. After retraction of the wash cup and de-energization of the blot solenoid, carrier 22 is rotated an additional 90 degrees. The blot solenoid is again energized and the photoresponsive unit 40 is activated to read the color of the standard pad, compute and display the glucose level and energize the "stand." light. After de-energization of the blot solenoid, the carrier is rotated an additional 90 degrees and the color of pad 28 is read, the glucose level is displayed and the "sample" light is energized. At the conclusion of this measurement, the glucose reading can be retained on display 150 and the carrier is rotated a further 90 degrees to its original position and the sample holder is extended for removal of the test strip and insertion of a further strip for a subsequent test. Removal of the strip depresses the holder, again closing the contacts on strips 48, 49 to provide another start signal. However, this start signal is interpreted as an "end" signal in response to which the strip holder is retracted to prevent accidental damage to it. If no further test is to be run, the new strip should, of course, not be inserted. Instead, the unit is simply de-energized by depressing "OFF" switch 148. If a new test is to be run, the new strip is inserted and "Reset" switch button 147 is depressed causing the routine to return to the beginning to check for adequate air, water, and power. The standard strip should also be removed and replaced.
While one advantageous embodiment has been chosen to illustrate the invention, it will be understood by those skilled in the art that various changes and modifications can be made therein without departing from the scope of the invention as defined in the appended claims.
|Cited Patent
|Filing date
|Publication date
|14 Feb 1966
|13 Feb 1968
|Scientific Industries
|Automatic chemical analyzer
|30 Nov 1967
|23 Feb 1971
|Robert R Young
|Methods and means for handling blood test specimens
|24 Jul 1974
|11 Nov 1975
|Olympus Optical Co
|System for detecting the particular chemical constituent of a fluid
|23 Jul 1974
|13 Jan 1976
|Olympus Optical Co., Ltd.
|System for detecting the particular chemical component of a test fluid
|3 Jun 1975
|28 Dec 1976
|Olympus Optical Co., Ltd.
|Apparatus for automatic application of blood serum
|4 Apr 1975
|25 Jan 1977
|White Ronald D
|Apparatus for preparing microscope slides
|23 Feb 1979
|2 Sep 1980
|Coulter Electronics, Inc.
|Backwash system for diluting apparatus
|16 Jun 1980
|20 Oct 1981
|Eastman Kodak Company
|Apparatus for processing an analysis slide
|15 Apr 1980
|19 Jan 1982
|Olympus Optical Company Limited
|Delivering apparatus
|4 Nov 1981
|13 Dec 1983
|Fuji Electric Company, Ltd.
|Blood sugar analyzer having fixed enzyme membrane sensor
|20 Oct 1980
|10 Jan 1984
|Vitafin N.V.
|Simultaneous, kinetic, spectrophotometric analysis of blood serum for multiple components
|Citing Patent
|Filing date
|Publication date
|11 Feb 1988
|22 Oct 1991
|Lifescan, Inc.
|Analytical device for the automated determination of analytes in fluids
|20 Jul 1989
|5 May 1992
|Societe D'applications Des Techniques Photoniques
|Artificial pancreas
|21 Mar 1995
|8 Oct 1996
|Lifescan, Inc.
|Whole blood glucose test strip
|9 Aug 1996
|7 Apr 1998
|Lifescan, Inc.
|Remote-dosing analyte concentration meter
|30 Sep 1997
|1 Dec 1998
|Lifescan, Inc.
|Automatic initiation of a time interval for measuring glucose concentration in a sample of whole blood
|13 Oct 1998
|17 Jul 2001
|Bayer Corporation
|Spectrophotometric apparatus with reagent strip detection
|28 May 1999
|31 Jul 2001
|Lifescan, Inc.
|Reflectance measurement of analyte concentration with automatic initiation of timing
|24 Nov 1999
|1 Oct 2002
|Home Diagnostics, Inc.
|Protective test strip platform
|28 Feb 2001
|25 Feb 2003
|Home Diagnostics, Inc.
|Method of strip insertion detection
|28 Feb 2001
|1 Apr 2003
|Home Diagnostics, Inc.
|Method for determining concentration of an analyte in a test strip
|28 Feb 2001
|13 May 2003
|Home Diagnostics, Inc.
|Distinguishing test types through spectral analysis
|24 Jun 2002
|23 Nov 2004
|Lifescan, Inc.
|Reagents test strip with alignment notch
|17 Apr 2008
|3 Apr 2012
|Iris International, Inc.
|Chemistry strip reader and method
|23 Dec 2013
|21 Feb 2017
|Cilag Gmbh International
|Test strip connector contact protection
|23 Sep 2002
|20 Mar 2003
|Roger Phillips
|Minimum procedure system for the determination of analytes
|24 Jun 2002
|17 Apr 2003
|Roger Phillips
|Minimum procedure system
|24 Jun 2002
|17 Apr 2003
|Roger Phillips
|Minimum procedure system for the determination of analytes
|4 Mar 2003
|24 Jul 2003
|Home Diagnostics, Inc.
|Distinguishing test types through spectral analysis
|17 Apr 2008
|30 Oct 2008
|Dale Capewell
|Chemistry strip reader and method
|17 Apr 2008
|30 Oct 2008
|Dale Capewell
|Chemistry strip reader and method
|7 Jan 2011
|28 Apr 2011
|Dale Capewell
|Chemistry Strip Reader And Method
|23 Dec 2013
|25 Jun 2015
|Cilag Gmbh International
|Test strip connector contact protection
|20 Jul 1989
|8 Feb 1990
|Societe D'applications Des Techniques Photoniques
|Artificial pancreas
|18 Nov 2002
|30 May 2003
|Quidel Corporation
|Test strip analysis apparatus
|U.S. Classification
|422/63, 422/82.05
|International Classification
|Cooperative Classification
|European Classification
|19 Nov 1984
Owner name: TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER, SCHO
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNOR:BARNETT, J. CRAIG;REEL/FRAME:004337/0402
Effective date: 19841112
Owner name: TEXAS TECH UNIVERSITY HEALTH SCIENCES CENTER,TEXAS
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:BARNETT, J. CRAIG;REEL/FRAME:004337/0402
Effective date: 19841112
|9 Aug 1991
|Maintenance fee reminder mailed
|5 Jan 1992
|Lapse for failure to pay maintenance fees
|10 Mar 1992
|Expired due to failure to pay maintenance fee
Effective date: 19911229


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Click on the image for a better look.With the start of the school year, I lost some of the momentum I had during Week 1. I had to set up my classroom and otherwise prepare for being an art teacher again. Now the kiddies are back and school is in full swing. There were several days that I did not draw (SO tired!), but for the most part I was good about doubling up the next day. I had some great photos to work from, and I'm proud of this week's drawings.
Next up: Hoss the St. Bernard, Mia the Maltese, Casey the Beagle, Sammi the Basset Hound, Hannah the Pekingese, Brackett and Kali, both mixed breed dogs.

subset: commoncrawl


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Languages are integral to our identity, our heritage, and our humanity. With most of the world's languages severely threatened, thousands of language communities have committed to revitalization efforts, from documentation and renewal to revitalization and maintenance. These efforts respond to the urgency of the situation in the absence of robust comparative research.
At the Smithsonian Center for Folklife and Cultural Heritage, we believe that sustained efforts in language revitalization and the accumulated literature on these efforts are at a point where larger-scaled comparative analysis and synthesis is possible. To address this need, we have developed an interdisciplinary research program, Sustaining Minority Languages in Europe (SMiLE), that seeks to examine autochthonous or minoritized language revitalization initiatives in Europe in a more systematic manner.
Call for Proposals
SMiLE invites proposals for community-situated ethnographic and sociolinguistic research around a series of questions addressing the social, cultural, political, and economic factors that contribute to the vitality of minoritized language communities. We are particularly interested in creating comparable case studies that:
- reveal the trajectory of a community's language revitalization programs and efforts at various stages of their lifecycles;
- analyze how language revitalization and maintenance programs respond to internal and external social, economic, and political factors;
- explore relationships among language revitalization, cultural heritage, and traditional cultural transmission.
The complete description of the program and application materials are available in the right navigation bar.
Collaborative Research Awards
SMiLE will fund six teams of two or more academic researchers, community-based scholars, language advocates, policy experts, and others. Support is available for various combinations of fieldwork, consultation, project-related travel, and archival research for periods up to eighteen months. Each research team will be eligible for awards up to $120,800 USD.
Grantees are expected to present their works-in-progress at three workshops sponsored by the Smithsonian and collaborate with other grantees and SMiLE advisors to synthesize findings.
Eligibility to Apply
- Proposed research must be conducted in a European autochthonous or minoritized language community whose members are currently engaged in language revitalization or maintenance efforts.
- At least one Principal Investigator from each team submitting a proposal must have strong ties with the community or program of the research site. Ideally, one PI or supplementary partner or collaborator will be a community member.
- Preference will be given to teams with at least one Principal Investigator who holds a PhD (or other terminal degree) related to the study of language in society in one of the social sciences or humanities.
- Applicants should be able to demonstrate their ability to engage in ethnographically informed research in multiple social fields and language domains.
- Nationals of any country may apply.
Application Deadline:
September 1, 2017
SMiLE Research Awards are sponsored by the Smithsonian Center for Folklife and Cultural Heritage with funding from Ferring Pharmaceutics Inc.


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Player Profile
Tom Bailey, a graduate of Lancashire's Academy and Scholarship programmes, has little first-class experience, yet he has already proved he can be a bowler of great worth to the county.
Seamer Bailey made his first-class and County Championship debut in the closing stages of the 2012 season.
He had to be patient for his next chance, which came towards the end of 2014 following an encouraging run of form in one-day cricket, taking seven wickets in four 50-over matches, including a wicket with the sixth ball of his career against Essex at Chelmsford.
He played in three Championship matches against Durham, Yorkshire and Middlesex, taking three wickets in the latter fixture as well as demonstrating his prowess as a useful lower order batsman.
The Prestonian, a product of the Vernon Carus club, has been somewhat of a late bloomer in the game. He started out as an 11-year-old, but he did not play representative cricket for the Red Rose until Under 19s level.
After his encouraging end to 2014, he was given a longer run in 2015 as Lancashire successfully claimed Championship promotion from Division Two.
He claimed a career best 5-12 as Leicestershire were bowled out for just 78 in the second innings of a landslide win at Grace Road, while he also contributed to Lancashire's NatWest T20 Blast title success that summer.
Bailey's 2016 campaign was heavily disrupted by a side injury, ruling him out of action for the best part of two months.
In fact, he was away from first-team action for three months.
But he made an impressive return in three Championship matches, taking 12 wickets.
His 5-111 against Somerset at Emirates Old Trafford included four wickets in seven balls, helping to secure a crucial draw in the successful bid to secure Division One status.
He also claimed 4-52 with the new ball in the final round defeat against Warwickshire at Edgbaston.
Sandwiched in between those matches, he also hit a maiden first-class fifty against leaders Middlesex at Emirates OId Trafford, helping to secure another crucial draw.


text: In the fourth century B.C., a Greek merchant ship sank off Chios and the Oinoussai islands in the eastern Aegean Sea. The wooden vessel may have succumbed to storm, fire or rough weather, ruining the cargo of 400 ceramic jars of wine and olive oil. The ship went down in 60 meters of water where it remained unnoticed for centuries. The classical-era ship might never have divulged to archaeologists its clues to ancient Greek culture but for a research team from MIT, the Woods Hole Oceanographic Institute (WHOI), the Greek Ministry of Culture and the Hellenic Center for Marine Research (HCMR), who used a novel autonomous underwater vehicle (AUV) to make a high-precision photometric survey of the site last July. The robotic vehicle used at Chios is an AUV called SeaBed. The AUV scanned the scattered cargo and created a topographical sonar map. WHOI archaeologists and engineers are assembling the 7650 images into mosaics that depict the minute features of the shipwreck. The Chios wreck is playing a critical role in exploring how advanced technology can dramatically change the field of underwater archaeology. The researchers have now released a few photographs showing detailed images of some of the remnants of cargo lying on the ocean floor, where it's been since about 350 B.C. The researchers took more than 7,000 images, which will eventually be combined into one mosaic of the entire wreck. The new research project will last 10 years or more, focusing on uncovering evidence of ancient trade in the Mediterranean, particularly of the Minoan and Mycenaean cultures and their trading partners in the Bronze Age (2500-1200 B.C.). (Source: http://www.newindpress.com)


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So, it's time for the wedding of the year and everyone is invited. Yes, we are talking about the auspicious occasion of the marriage of Goddess Parvati to Lord Shiva.
Mahashivratri is also commonly known as Shivratri. It is celebrated to mark the meeting of Shiva and Shakti. This festival is celebrated by millions of Hindus across the world. The devotees flock to the temples early in the morning, worshiping the 'shivlinga' and offering milk, honey, water and bael or wood, apple leaves and dhatura flower to Lord Shiva.
Shivratri is said to be a favourable day to raise one's spiritual energy more easily. It is said that the planetary positions in the Northern hemisphere act as a catalyst along with the repetition of the powerful Maha Mrityunjaya Mantra that increases one's spiritual energy greatly on this night.
Devotees celebrating 'Shivratri' fast for the whole day. Though the Shivratri fasts are not as strict as compared to other Hindu fasts, some devotees don't even consume water on this day.
Majority of the devotees consume a fruit diet or non cereal diet along with water, nimbu pani or milk during the fast.
So, today, we are sharing some of the tips that will help you to stay energetic as well as healthy during the fast of Shivratri. Do have a look:
Don't Overeat The Previous Night
Please refrain from overeating in the night. If you have to fast on a particular day and you think that overeating in the night will sustain you the next day, you are absolutely wrong. Overeating at night will only end up in making you feel bloated and clogged the next day. You might also end up feeling irritated the whole day with all that undigested food in your gut.
Keep Your Meal Simple And Light The Previous Night
Try to have a complete meal the previous night though not in a very large quantity, include lots of vegetables, legumes, fruits with natural sugar and lowglycaemic fruits like berries. This kind of a balanced meal will give your body a slowburning nutrition that'll last the next day during your fast.
Drink Lots And Lots Of Water
Whether you drink normal water or nimbu pani, drink lots of it. Drink a glass of any of the drinks between an interval of one or one and half hours. You can opt for fresh fruit juices, nimbu pani, coconut water and a wide range of only natural drinks.
Refrain from adding syrups or artificial flavours in your drink; they might have ingredients such as artificial colours or preservatives that could lead to stomach troubles, since you are on a fast. However, you can add glucose powder to your normal water to boost your energy levels.
Eat At Regular Intervals
Staying hungry for a longer time might rise up the acidity level in your body and you might end up feeling uneasy. You also need energy to sustain yourself the whole day, so it is highly advisable to eat at regular intervals. Take at least six small servings throughout the day.
Take Small Servings Of Food
Eating at regular intervals does not mean loading yourself with food. If you end up eating the whole day, what's the point of fasting, right?
Take a small serving of food throughout the day. These small servings should only be small portions of fruits, may be half an apple or a banana that'll give your body the required nutrition.
Do Not Miss On Your Regular Medicines
If you are a heart patient, BP patient or suffering from any chronic health problem, then do not miss on your prescribed medication. Take your medication on time.
There's no point of fasting risking your life, even God won't appreciate that.
Take Proper Rest, Don't Over Exhaust
During a fast, it is advisable to keep yourself engaged. Sleeping all day or watching television might give you a bad headache or make you feel dizzy. If you are working, go to work. People staying at home utilize the day in some DIY craft or anything that is creative.
This will keep you occupied and divert your mind from the thought of food. Whatever you do, do not exhaust your energy levels because you already have less of it and have to sustain yourself for the whole day.
Stay Prepared For The Fast Emotionally
Prepare your mind before the fast. There's no point of observing a fast when you are thinking about food all the time. Don't let your hunger pangs disturb your spiritual connection with God. Also, keep all the tempting food away from your kitchen counter or fridge. You could hide them.
Remember, 'out of sight is out of mind'!
Do Not Stress
Again do not stress yourself a lot. Stressing yourself will also disturb your connection with God as well as exhaust your energy levels. Keep your mind free and clean from any kind of turbulence. Meditate!
Do Not Stuff Yourself The Next Day
The next day after your fast, avoid overeating. It's just been a day since you last saw food and not ages. So, keep your food simple and nutritious for the next day. Avoid harddigesting foods, instead eat light small portions. Give your metabolism sometime to come back into its original form.


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4 followers! Cool!
So yeah, quick update on all things me;
1] Zenith Comics Presents: Supervillains! Vol 1 for BASH was number 1 at RPGnow for 3 days and in the top ten of the Top 100 for 2 weeks now! V&V, while sales are good, not as high ratings.
2] Moving back to Vancouver and my acting career in May. Wish me luck.
3] Feeling mostly okay but had enough of winter.
That's a fast and dirty update, more to come when I think of it ;)
Friday, March 4, 2011
I Suppose An Update Is In Order
1 comment:
Moving back to Vancouver? Man, you might as well have stayed there in the first place. ;-) Too bad really. Looks like I'll be in Canada this summer, but Vancouver isn't exactly on the way from Germany to Regina or I might have swung by your place. Maybe another time.ReplyDelete
Nevertheless, good luck with the move and the acting career, mate.
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Written on: 02/11/2012 by glynm (1 review written)
I ordered a Trek hybrid bike from a special offer advertised on the website. There was strong demand and all the stock of that particular model had ben sold, however Evans immediately offered a newer model as an alternative at no extra cost! Collected from the store at The Chill Factory where the bike was prepared while I waited and was fitted with the extras that I had asked for.
All the staff that I came in contact with were knowledgeable and courteous.


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I will paint anything--probably even things that shouldn't be painted. So when I saw this rather hideous mirror at the local Salvation Army for $8, I saw potential, as long as I could paint it. I actually walked by it for a couple of weeks (so did everyone … [Read more...]
Archives for August 2011
Trash to Treasure–Painted Plastic Thrift Store Mirror
"Apple of my Eye" Baby Shower
Last year my dear friend Sara was pregnant with her 4th child and her 1st boy. She has 3 adorably sweet little girls so I knew that she needed a bit more blue added to her baby wardrobe. Being a mom of two boys, I felt it was my duty to shower her with love and a bit of advice when it comes to on … [Read more...]
Things I have learned from building a house…
I admit that I am a bit house-obsessed. I am not afraid to say it. I like things in my house to be neat, and look how I want them to. I have often said, I want visitors to feel welcome and comfortable and my children to grow up in a home with a sense of peace and security. {As I write this, I … [Read more...]
Moving On…
I have been absent from blogging for awhile. I forgot (or blocked out!) how difficult it is to move. This time just about pushed me to the brink, between packing, finding a new house, the school year ending and working on a major project all in about a month. I think I am still mentally recovering … [Read more...]


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This. Looks. Epic! Go on, take a gander at all the new goodies the 35th anniversary of John Carpenter's Halloween will be bringing you below. Remember, the boogeyman is real!
The Facebook page fo the Halloween franchise has revealed the art for the upcoming Halloween: 35th Anniversary Blu-ray and it's pretty goddamn amazing. Details on the release below!
For this very special release, Anchor Bay and Trancas International went back to the vaults to present this legendary terror classic as never before, including creating an all-new HD transfer personally supervised by the film's original cinematographer, Academy-Award nominee Dean Cundey, a new audio mix (as well as the original mono audio), a brand-new feature length audio commentary by writer/director John Carpenter and star Jamie Lee Curtis, an all-new bonus feature with Ms. Curtis, as well as selected legacy bonus features from previous ABE releases.
Available in a collectible limited-edition book-style package (available only for the first printing) with 11 pages of archival photos, an essay by Halloween historian Stef Hutchinson and specially commissioned cover art by Jay Shaw.
" Anchor By Entertainment has been home to Halloween for almost 20 years," noted Malek Akkad, President of Trancas International Films and son of Moustapha Akkad. "I'm so happy that we're partnering with them to present the definitive edition of what is widely acknowledged as one of the seminal horror films of the 20th century.
Bonus features on Halloween 35th Anniversary Blu-ray include:
- All-new commentary track with writer/director John Carpenter and star Jamie Lee Curtis;
- "The Night She Came Home" new featurette with Jamie Lee Curtis (HD)
- On Location
- Trailers
- TV & Radio Spots
- Additional Scenes from TV Version
Like what you see? Be sure to also visit Pissed Off Geek too for more news and reviews with a horrific edge. To stay up to date with the latest horror news and reviews from the site be sure to "like" Truly Disturbings's Facebook page and following us on Twitter!


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TIC Gums introduces new yogurt application
Yogurt continues to be a popular product in the dairy category due to its versatility, convenience and source of high quality protein.
As dairy manufacturers expand product lines with new options for consumers, many are challenged to maximize nutritional value and still deliver products that appeal to the market.
Hydrocolloid systems play a role in yogurt as they balance the texture consumers expect with syneresis control (the tendency of products to release water during storage) and protein stability.
Dairyblend YG OG 6 enhances attributes such as mouth coating and viscosity, allowing formulators to address their functionality needs while achieving the textural characteristics consumers look for in indulgent products.
Increasing interactions with water
Donna Klockeman, Sr. principal food scientist at TIC Gums told DairyReporter that the texture and stability of yogurt results from the combination of the protein network and any stabilizers added.
"Dairyblend YG OG 6 contributes to the texture and stability of yogurt through a two pronged approach," Klockeman said.
"The first, to enhance the thickening and gelling characteristics of the protein network, which occurs as a result of the drop in pH during the culture process. The second, to increase interactions with water thus delaying syneresis."
Fits with organic requirements
Yogurt produced with Dairyblend YG OG 6 has increased viscosity and mouth coating to enhance the perception of fat content and aid in flavor delivery without dissolving too quickly.
Dairyblend YG OG 6 also aligns with 95% organic requirements in accordance with the USDA's National Organic Program.


text:
Cops: Caught in the Act Trailer (2004)
This collection gathers some of the most outrageous segments of "Cops," featuring those crooks unlucky or dumb enough to get caught while committing a crime. But these bad boys don't go down easy, and the police use every trick to arrest them.
Watch the official Cops: Caught in the Act 2004 trailer in HD below or find more Cops: Caught in the Act videos on Vidimovie.


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Brunette slut with big nipples makes her cunt huge with pussy pump
Description:Dark and long haired horny harlot in sexy black stockings and with giant nipples rests with legs spread and plays with funny pussy pump hard. Look at that dirty solo in Wet and Puffy porn video!
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text:
The Manchester United star Juan Mata appears to be in a relaxed mood this summer despite speculation linking him with a move away from Old Trafford.
The 29-year-old has uploaded a series of pictures documenting his travels in Spain.
Mata's place at Man Utd has been put in doubt following Jose Mourinho's appointment in place of Louis van Gaal.
Mourinho offloaded Mata from Chelsea to United during his second spell with the Blues. The Spanish newspaper El Confidencial have claimed the Portuguese manager is open to selling Spain Mata over the summer transfer window.
Mata has been frequently linked with a loan move to Fenerbahce over the past fortnight. The Express newspaper has reported that Juventus are also interested in the £30 million rated playmaker.
Fenerbahce signed both Robin van Persie and Luis Nani from the Manchester United over last summer's transfer window.
The Spain international scored 10 times while providing 11 assists for United last season and has another two-years left on his contract.
See More
Arsenal's Mesut Ozil pictured alongside Liverpool star
Besiktas to make offer for Liverpool defender says agent despite reports of £5.5m deal


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[hand-bag] /ˈhændˌbæg/
a or box of leather, fabric, plastic, or the like, held in the or carried by means of a handle or strap, commonly used by women for holding money, toilet articles, small purchases, etc.
plural noun
(facetious) an incident in which people, esp sportsmen, fight or threaten to fight, but without real intent to inflict harm (esp in the phrases handbags at dawn, handbags at twenty paces, etc)
Also called bag, (US and Canadian) purse, (chiefly US) pocketbook. a woman's small bag carried to contain personal articles
a small suitcase that can be carried by hand
a commercial style of House music
plural noun
a harmless altercation; trouble; also called handbag situation
When they discover we've spent the Christmas savings, it's going to be handbags.
Word Origin
abbr. of handbags at dawn
Usage Note
British slang
also hand-bag, 1854, from hand (n.) + bag (n.).
Tagged: h
Read Also:
- Handbags at dawn
noun See handbag situation See handbags at ten paces
- Handbags at ten paces
noun a weak but theatrical confrontation, harmless altercation; a verbal spat resembling a duel; also called handbags at dawn , handbag situation Examples What's it to be, handbags at twenty paces? Word Origin 1987
- Handbag situation
noun a weak but theatrical confrontation, harmless altercation; also called handbags at dawn See handbags at ten paces plural noun See handbags Word Origin imitation of women fighting with handbags
- Handbarrow
[hand-bar-oh] /ˈhændˌbær oʊ/ noun 1. a frame with handles at each end by which it is carried. 2. a handcart. /ˈhændˌbærəʊ/ noun 1. a flat tray for transporting loads, usually carried by two men


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Sambô - Estação Sambô Ao Vivo Trailer (2012)
"Everyone will want to stay in this season!" 30 November 2012 Music 106 mins
Mixing samba to various styles such as pop, rock and MPB, the Sambo group is hitting stores with his second job: Sambo Station - Live. The DVD features appearances by Sidney Magal (from "Proud Mary"), Thiago (the "Debt"), Di Ferrero, NX Zero (in "The Blind Castle"), and Pericles (on "Feeling it hurts "and" Leave "). In their presentations, the group relinquishes the conventional stage to prioritize contact with the fans: they prefer the wheel (meaning the origin of samba) and choose to keep it as low as possible, providing greater interaction with the public . A group of scholars, irreverent, committed, fun and, above all, authentic musicians, that brings these launches the diverse cultures of Brazil. Everyone will want to stay in this station!
Watch the official Sambô - Estação Sambô Ao Vivo 2012 trailer in HD below or find more Sambô - Estação Sambô Ao Vivo videos on Vidimovie.


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One increibly lucky winner received R49 620.00 after taking a R20.00 multiple bet.
A second punter won R95 000.00 after betting on an international friendly.
The Australia South Africa ODI this past week saw 2 cricket betting enthusiasts win R53 500.00.00 and R49 000.00 respectivelyafter selecting the match winner.
BetXchange remains the country's leading betting enterprise having been established by the well-respected Keith Ho in 1988. BetXchange started off as a horse racing betting stop but within a short space of time introduced sports betting and was at the forefront of bringing this option to the South African market. With world class facilities, well-informed betting clerks and a reputable, reliable website, BetXchange offers betting on all sports and has a wide variety of markets to choose from. BetXchange led the introduction of betting spreads and exotics and stays ahead of the pack when it comes to pricing and new innovation in the industry. In recent years we have also introduced a variety of exclusive Social Media (Facebook and Twitter) specials to improve your sports betting experience.
Sports betting is arguably the fastest growing phenomenon in the South African sporting front. In South Africa betting has always been associated with horse racing but over the years punters have taken to sports betting and have embraced it with the same passion they have for their favourite sports. Keith Ho BetXchange is South Africa's leading sports betting company and we offers specialized and comprehensive local and international betting on horse racing, rugby, soccer, tennis, golf, motorsport and more. Additionally we offer extensive in house and online sports betting facilities. At BetXchange we offer our customers the most competitive prices available in the world and with the largest amount of various sports betting options available in South Africa.
The local South African market has seen a huge rise and interest in spread and exotic betting which have now become part and parcel of most high-profile matches and events around the world in leading sports such as rugby, cricket, soccer, golf, tennis, motor sport and lotto divisions. Huge winning possibilities are available on the more technical and tactical spread and exotics betting markets. A trained team of sports traders and analysts are always willing and ready to assist with any kind of bet and punting situation while a 24-hour special customer service is also available on request. At BetXchange we have every event and every market that you need when it comes to sports betting.
Keith Ho BetXchange has been a licensed bookmaker since 1988 and underwent a rebranding in 2002. Keith Ho BetXchange is South Africa's leading sports betting
company, offering specialized and comprehensive local and international betting on horse racing, rugby, soccer, tennis, golf, cricket and motorsport.
Keith Ho BetXchange has extensive in house and online sports betting facilities with world class sports traders available 24 hours a day to make your betting experience
one to remember. All of the BetXchange staff pride themselves on offering customers top notch service, the most competitive prices available in the world and the
widest range of fixed odds and exotic markets available in South Africa. The In-Play betting service that BetXchange offers is the largest in South Africa
covering all major sports and sporting events. We lead, others follow.
Copyright © 2014 Keith Ho BetXchange. Keith Ho BetXchange operates under licenses in Gauteng, Free State, Mpumalanga and the Western Cape. National Responsible Gambling Programme Toll Free Helpline: 0800 006 008. No persons under the age of 18 are permitted to gamble. We lead, others follow. All bets taken fall under the terms and conditions of Keith Ho BetXchange


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MOVIE SYNOPSIS [ General Audiences ] Martin, a young student, was injured during a swimming lesson. Sebastian, the gym teacher, takes him to the hospital. When leave is offered to take him home but Martin was going to sleep that night with a colleague considering that no one at home. You can watch Ausente online on TV cable or theaters with original audio in Spanish at different dates. This film premiered in theaters in 2011.
Rating: 5 by 1095 users./
Runtime: 91 minutes
Carlos Echevarría, Javier De Pietro, Antonella Costa, Alejandro Barbero, Rocío Pavón, Luis Mango, Lautaro Machaca, Joan Alsina, Nicolás Fernández Rubio, Laura Dozo, Alejandra Lang, Fabio Cendra, Dolores Cano, Constanza Boquet and Liliana Popovich.
Drama, Thriller.
91-minute film (full movie) directed by Marco Berger.
The original audio of Ausente has dialogues in or Spanish, it was produced in Argentina.
It premiered in cinemas or television in 2011.
Screenplay written by Marco Berger.
Tomás Pérez Silva.
Mariana Contreras, Marco Berger and Pablo Ingercher Casas.
This film was produced and / or financed by Oh My Gomez! Films and Instituto Nacional de Cine and Artes Audiovisuales (INCAA).
Composed by Pedro Irusta.
Bodega Films, Homescreen, Outplay and PRO-FUN media Filmverleih.
Without commercial breaks, the full movie Ausente has a duration of 91 minutes; the official trailer can be watched in streaming on the Internet. You can watch this full movie free in English or Spanish in movie TV channels, renting the DVD or with VoD services (Video On Demand player, Hulu) and PPV (Pay Per View, Netflix).
See the page of this full movie, Ausente in FULLTV Movies.


text: Hi All, yesterday i took my car to one of the garage for servicing where he noticed that there is oil Lead inside the AC Coolant Compartment , He removed the A.C coolant Compartment and saw huge amount of oil inside it . He cleaned the whole thing and put fresh coolant and told me to check for a day and see if again Oil Leaks traces are seen or not . Today morning i checked it and i feel there is again Oil Traces inside the AC coolant compartment. Please advise what would could be the issue over here and what needs to be done now .


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GraphicRiver Corporate Business Postcards 11386473
Category: Print Template | Comment: ( 0 )
GraphicRiver Corporate Business Postcards 11386473
Print Template \ Cards & Invites
Postcard \ Flyer \ Business \ Corporate \ Company \ Online \ Solutions \ Strategy
Print Template - Corporate Business Postcards 11386473 by afjamaal @ GraphicRiver
Print Template \ Cards & Invites
Layered: Yes; Graphics Files Included: Photoshop PSD; Minimum Adobe CS Version: CS4; Print Dimensions: 210x297.
Corporate Business Postcards.
This Postcard is made in photoshop the files included are help file and photoshop psd's. All psd's are very well organized proper name groups and proper name layers. Very easy to edit very easy to insert images very easy to change text. Image placeholders are smartObjects to make easy for you to add image. And edit file.
We are always available to help you and you can contact us from our profile or comments on this product 24/7. We can also change text and images for you. NO CUSTOMIZATION!
We do not provide fonts, or images you are seeing in previews. But we can give you links for fonts and images.
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Insomniac's Playlist
Oh Wonder's Josephine on the songwriters that inspire her
From Joni Mitchell to Vanessa Carlton, Josephine Vander Gucht of the duo Oh Wonder tells us about the female songwriters that inspired her to create music
Added on
Joni Mitchell, Norah Jones, Carole King, Regina Spektor and Vanessa Carlton are not only rare and brilliant artists, but also incredible songwriters and instrumentalists. These five songs were written solely by the artists that sing them - there are no co-writers on any of these tracks, and the singers all play the piano or guitar that accompanies them. This incredible sense of female autonomy really inspired me as a teenager, and empowered me to write songs and perform them myself. Without these artists, I'm not sure I'd have ever started writing songs...


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Puppy: Stella
Friends: 0
Member Since: May 7, 2012Add to Friends
My name is Stella and I am a Goldendoodle. My favorite hobbies are stalking birds, (especially robins!) going to the dogpark, playing catch with tennis balls and chewing on my elk antler. I'm very excited to learn to swim this summer!View Profile


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Williams Sister Snag 3rd Olympic Tennis Gold
Williams Sister Snag 3rd Olympic Tennis Gold
38 results for 'gold medal'. Showing results 19 - 36
Williams Sister Snag 3rd Olympic Tennis Gold
US Swim, Gymnastics Teams Scoring High
US Snags Gold Medals in Swimming, Skeet Shooting
Olympic Athlete Runs for Gold to Honor God
First Black Marines Receive Congressional Medal
It is truly a feat that Vonetta Flowers switched sports from track and field to bobsledding and won an...
Going for the gold… It's a dream many share but few ever experience. Eric Bernatos is one of those...
Now that the Olympics are over, some are wondering where China goes from here.
As thousands prayed in Washington D.C., miles away in Beijing, Olympic athletes were also meeting for a weekend of prayer.
As millions of Chinese catch Olympic fever, fitness is becoming a bigger part of their lives.
Ryan's been running since he was 14 years old. Time has taught him that seeking to please God is...
Four weeks from tonight, the world will be watching as athletes arrive in Beijing for the opening ceremony.
This Olympic gold medalist has topped NCAA records, pitched her way to first place in the 2001 College World...
The Women's Olympic team softball coach has triumphed through life's adversities with God's help and managed to lead his...
The Olympic Gold Medal skater shares his secrets to finding happiness in the face of a life filled with...
Former WASP Sought a Higher Honor
Team U.S.A. Wins Three Gold Medals in One Day
Female WWII Pilots Honored with Gold Medals


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Last season, Atlanta Falcons LT Sam Baker missed a dozen games with a torn patella tendon in his left knee. He exited Saturday's preseason game with the Houston Texans, and it appears that it may be a repeat of the same injury -- only to his other knee.
"The early diagnosis for #Falcons LT Sam Baker is a torn patella tendon, per source. If tests confirm, would almost certainly end his season," tweeted NFL.com's Ian Rapoport.
The Falcons inserted Lamar Holmes at left tackle when Baker went down last night. However, if Baker is done for the season, then the long-term solution for the Falcons likely will be in the hands of sixth overall pick Jake Matthews.


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One top affiliate earned a huge $247 commission this week from PokenZoo. We confirmed the order and I congratulated the affiliate on a job well done. The customer purchased the Poken Bride and Groom Set.
With the introduction of the Poken Bride and Groom set, PokenZoo can make the reception an even more memorable event. With Pokens on every place setting, guests can tap the night away, and make your guest list their new friend list.
Standard order is 72 pieces (36 grooms and 36 brides).
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7 Day Average Sale: $1,236.11
Join PokenZoo on ShareAsale and get ready for our big Affiliate Summit East Meetup!


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CFC®-6140 is a high molecular weight block copolymer wetting and dispersing additive for organic solvent systems. This yellowish-clear liquid promotes flow property for coating systems of high thixotropic properties and provides anti-flooding and dispersing for high concentration pigments. CFC®-6140 improves gloss and levelling features, and acts as a wetting and dispersing agent for high oil absorption organic pigments. It finds application as a high concentration tinter, and in automotive, refinishing, and wood coating systems.
- Datasheet (英语)
Cheongwoo CFC® Co. Ltd. has been manufacturing and supplying specialty paint additives. These include additives for waterborne paint, OEM paint, industrial paint, plastic coating, wood coating and architecture paint. CFC® always put forth efforts to contribute quality improvement, cost savings for customers as well as high-tech research and development and quality control.


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Trump Administration Moves To Alter Drug Discount Program That Many Rural Hospitals Rely On
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Make-A-Wish Foundation; Holiday Travel With Kids; Pet Obesity; Turkey Tips, Chance The Rapper On SNL
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Teen Moms In Some States Are Denied Pain Relief During Childbirth
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New County Budget Leaves Nursing Home Future Undecided
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Disagreeing During Thanksgiving; Hiring More Minority Firefighters; Helping People With Dementia
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Rep. John Conyers Acknowledges Settlement, But Denies Sexual Harassment Claim
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Illinois Teacher Shortage; State Politics Updates; Urban Birds
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Thanksgiving Gas Prices Higher Than A Year Ago
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Texas Woman Charged With Mailing Explosives To State's Governor And Obama
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This large crystal diamond is crafted out of 24% Lead Crystal and is etched with the state seal of Ohio on the face.
This diamond has many facets and the way it reflects light is something that has to be seen to be believed!
4 inches diameter


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32 tracks entered. That got whittled down to 16, then four, and finally just two contenders to the title of my Song of the Year 2013.
So here we are, finally, at the end of the line. In the pale blue trunks, The Juan Maclean's Feel Like Movin'; in the red-of-an-unbidden-dawn trunks, Mark Kozelek & Jimmy LaValle's Gustavo.
So here we are, finally, at the end of the line. In the pale blue trunks, The Juan Maclean's Feel Like Movin'; in the red-of-an-unbidden-dawn trunks, Mark Kozelek & Jimmy LaValle's Gustavo.
Only one can emerge triumphant. Who will it be?
Late last year, I found myself, at 4am, in a drained bathtub with Chris 'Total Man Crush' Sparrow, a gin & tonic and a single portable speaker. The bathroom was the only room in my flat not occupied by a sleeping girlfriend, and we sat for an hour or so, passing the cable back and forth and rattling through our favourite songs of the year.
When we finally called it a night, and climbed out of the tub, I stuck on one last song: Feel Like Movin'. And we started to dance, a little self-consciously – we're two awkward guys, directly facing each other in a tiny bathroom – but irresistibly, arms above our heads, hands describing endlessly complex tesseracts in the air.
Feel Like Movin' is less the song's title, and more a list of associated side effects. I'm listening to it as I type this, and tugging Corgiton, our rotund stuffed corgi, around by one paw to the music, always rising, pushing towards the sky, as Nancy Whang sings "good time's going to take you to heaven". And Corgiton is keeping perfect rhythm.
Given that I'll defend with my life the position that all culture – films, games and especially pop songs – are best when they're short, it's pretty odd that my two contenders for the year's best song both clock in over the seven minute mark.
With Gustavo, I barely feel it. It's too easy to get caught up in Kozelek's elliptical storytelling, an ear always tuned to what happens next, waiting for the next killer line (the bit that landed as I wrote this sentence: "My house ain't done but it's alright/Floors ain't level, but I ain't some suburban/Who cares about bathroom tiles/Straight lines and building codes and Chinese wind chimes.")
But Feel Like Movin' wears its lengthy running time a lot more obviously, pretty much entirely because my enjoyment of the song is more physical.
Jumping back to dancing in the bathroom: it was great, but by the sixth minute we'd started to burn out. The flesh is weak, after all, and suddenly Nancy Whang's refrain of "Get your feet on the dancefloor/And show me what you're made of" started to feel like a challenge. Apparently, what we were made wasn't enough.
(There is a radio edit, which shaves a minute and a half off, which is actually a full from-the-ground-up remix. Weirdly, though it's not the version I first heard on the radio – Lauren Laverne's 6Music show, specifically – and it messes with the delicate balance of the full song, which is structured with the intricacy of a Stewart Lee set. Once you've listened to it a few times, you realise it's constantly builds up punchlines. The rest of the song teases, pulls away just as you think it's delivering on the set-up and moves on. Then, just as you're forgetting, all the punchlines are triggered at once.)
The aforementione Chris Sparrow is also responsible for introducing me to Mark Kozelek.
Sparrow's the kind of person where the question "what are you listening to?" can fuel pub conversation for hours. He was off on a tear about the Perils from the Sea album, sharing wry lines with that uncanny accuracy of his, laying out the vague overarching story, explaining where it fit alongside Kozelek's other work.
I was ready to dismiss it as just more Chris Sparrow Music: old American men being seductively miserable, glass of whisky in hand, as the dust creeps in through the cracks. But then he mentioned Jimmy LaValle's electronica-infused beats, and my ears pricked up.
I still haven't dipped into the rest of Kozelek's output, the stuff without LaValle. Partly because there's a fearsome amount of it – the guy released three albums in 2013 alone – and partly because... do you remember how in a previous post I mentioned how I was avoiding anything else by The Juan Maclean? It's the same deal.
These songs feel pure, untouched by anything else, and I worry that nothing else could live up to it.
But honestly, I'm romanticising my stubbornness and ignorance. Tomorrow, once this is all behind me, and 2014 officially begins in my head, their respective back catalogues are going to be my first port of call. I already know I'm wrong about Kozelek, anyway:
Jumping back again, a couple of hours before climbing into the bath: We're in the living room, enjoying the full aural benefits of our soundsystem. Sparrow stuck on a demo of You Missed My Heart, a track which very nearly ended up representing Perils From The Sea in this tournament, but this version is an acoustic live thing. Just Kozelek's voice and the occasional plucking of a guitar – exactly the kind of music I'd identify as having no interest in.
The room goes silent.
The song is stunning, in the literal pin-you-to-your-seat sense. The four of us just sit there for six minutes, listening. Maybe it's the gin, but there's a lump forming in my throat.
The second it finishes, the girlfriends chide us for being so bloody intense, ask can we have something with a beat and words we can actually sing along to please?
The other day, Kirsty 'Esteemed Colleague' Styles asked me what metric I could possibly use to pick the winning song in this ridiculous venture of mine. I shrugged the question off, but it kind of got to the heart of the idea behind the whole thing.
End of year lists are silly. They pretend on some kind of objectivity, that Song x is definitively better than Song y, even if the writer doesn't believe that, because if you acknowledge the arbitrariness it all falls apart. A knock-out tournament felt it like it carried that to its logical extreme.
So, having already talked your ear off about it, I can't really explain to you why Gustavo is the winner, why it beat all those other equally great songs to become my official Favourite Song of 2013.
Honestly, it's not the song I'd expected to pick. As far as I was concerned a month ago, when I began this, it was pretty much a two horse race, and the horses in question were Feel Like Movin' and Hood Party. But right now, it feels perfect.
I never officially picked a Song of the Year for 2012, but I think it's pretty clear that it was either Swift's We Are Never Ever Getting Back Together, or Jepsen's Call Me Maybe: perfectly-formed gleeful, lightweight, short pop songs which were both huge hits and felt deeply personal.
Nothing ever took that crown in 2013. Instead, we had Robin Thicke. There was Get Lucky, of course, but it wore out its welcome. I had my fingers crossed for Ciara's Body Party or Tegan & Sara's Closer, but neither made a dent on the pop consciousness, and eventually melted away.
You could draw personal comparisons, too, if you hadn't already spent hundreds of words telling stories from your boring life. Suffice to say that 2013 never felt quite right to me. It was an in-between year, with few highlights and a lot of challenges.
Yeah, that feels perfect.


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The U.S. Foreign Corruption Practice Act ("FCPA") makes it unlawful and penalizes U.S. companies, their directors and executives if they pay directly or through third parties anything of value to foreign public officials for purposes of obtaining unethical economic benefits.
Many cases exist where multinational companies that have perpetrated actions prohibited by the FCPA were investigated and penalized by U.S. authorities. Those companies have had to pay millionaire fines. In certain cases, the executives of the companies involved in corrupt practices have also been penalized.
The scope of U.S. and several other countries' anti-corruption laws goes beyond their national borders. As an example of such international scope, below is examined a case where a multinational company was investigated and penalized in the U.S. due to corrupt practices committed in, among other countries, Ecuador.
Bridgestone Corporation ("Bridgestone") is a Japanese company that manufactures and sells industrial products. The company sought to sell its marine hoses (hoses that are used to transport oil from tanker-vessels to shore) in Latin America. Between years 1999 and 2007, a Bridgestone subsidiary made US$ 2 million payments to public officials of State entities in Argentina, Brazil, Mexico, Venezuela and Ecuador for purposes of achieving sales of its products.
The U.S. Department of Justice ("DOJ") filed a criminal accusation against Bridgestone on grounds of conspiracy to violate the FCPA. The company pleaded guilty in 2011 and agreed to pay a US$ 28 million fine1.
Furthermore, Misao Hioki, International Sales Manager for industrial products and responsible for authorizing those illegal payments during 2004-2007, was also indicted. He pleaded guilty in 2008 and was sentenced to 24 months imprisonment and ordered to pay a US$ 80,000 fine.
The above case demonstrates the reach of the FCPA on business activities in Latin America, including activities carried out in Ecuador. The companies, their subsidiaries, agents and franchisees – when subject to the FCPA – must maintain robust compliance programs to prevent and detect corruption practices that might result in substantial sanctions against the company and its executives.
[1] The DOJ accusation also included charges for participating in a collusive agreement with other manufacturers of marine hoses in violation of the Sherman Act (competition law). Both Bridgestone and its International Sales Manager admitted being guilty of that violation.
The content of this article is intended to provide a general guide to the subject matter. Specialist advice should be sought about your specific circumstances.


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Description of the Accommodation
Rooms, services Six comfortably furnished rooms are offered by Al Tuscany B&B Lucca to guests looking for accommodation in Lucca. Your valuables can be the safely secured in the safe. You can find the exact list of services provided by Al Tuscany B&B Lucca (including those for extra fees) and the exact equipment of the rooms on the information sheet below.
Payment Advance payment by credit card or providing credit card guarantee may be necessary for finalizing the reservation, depending on the chosen date, room and price.
Arrival, opening hours The earliest arrival time is 15:00, the latest time to leave the rooms is 11:00. The personnel speaks Italian and English.
Al Tuscany B&B Lucca rooms Rooms
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Pet friendly, Elevator, Safe deposit box
Hairdryer, Desk in the room, Tea/coffee-maker


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Milan remain in Fabiano hunt
AC Milan are refusing to give up in their efforts to land Seville striker Luis Fabiano.
Last Updated: 17/07/09 2:20pm
AC Milan are refusing to give up in their efforts to land Seville striker Luis Fabiano.
The Rossoneri have already seen one bid for the Brazil international dismissed out of hand by his current employers.
That approach is believed to have fallen some way short of the buy-out clause in the players contract and Sevilla are reluctant to part with the forward for less than they feel he is worth.
While refusing to be held to ransom in their efforts to prise Fabiano away from the Spanish giants, Milan executive president Adriano Galliani admits the Italians are still hopeful an agreement can be reached.
"We made an offer that we considered to be correct," said Galliani on Fifa's official website.
"If the Sevilla president (Jose Maria Del Nido) considers our €14million (£12.1m) offer to be ridiculous, lucky him.
"The negotiations will continue even though there is a gap from the asking price and our offer. We shall see."


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hey guys..what do you expect from randy johnson today???????????anybody???
hey guys..what do you expect from randy johnson today???????????anybody???
hope he still has the momentum from the Tigers.
Well it IS a later starting time, so you're ok.Originally Posted by bill parcells
Holy christ - now Giambi's out of the lineup today!
So today, no:
- A-Rod
- Sheff
- Matsui
- Giambi
- Mariano
I don't know how we are still 1/2 game out.....
We are in serious need for some youth.I mean Serious!!!Originally Posted by WWalker85
why is AROD out???
He's got the flu huh, as long as it's not a real injury
cairo will hold down the fort for a day or 2
If only we could cut out that first inning, on that one bad pitch.. it woulda been a great start... Either way, it was a good enough start, 7IP, 3ER.... And the end result is a Yankee win!


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Strawberry Mousse Recipe
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text: The Navy's newest amphibious ship, the amphibious transport dock USS San Antonio is in production. USS San Antonio is the first ship of 12 amphibious ships that will support the Marine Corps' landing forces and embarked Marines in forward presence operations throughout the world. Designed to fully support Marine Corps missions involving amphibious or expeditionary maneuver warfare, as well as special operations, the ship has a flight deck for aircraft and a well deck for landing craft or tracked amphibious vehicles. Each ship can carry 720 Marines, land them by Advanced Amphibious Assault Vehicles, or fly them to their objective areas in a variety of helicopters or vertical take-off and landing aircraft. At 684 in length, 105 ft. in width, and displacing more than 25,000 tons, these ships are the second largest vessels in the Navy's 21st Century amphibious force. Designed for survivability, San Antonio's distinct profile is less vulnerable to detection, particularly with its Advanced Enclosed Mast/Sensor, replacing traditional "stick" masts. The ship also has two surface-to-air missile launchers for air defense and two high rate-of-fire stabilized 30mm guns for close-in protection against small boats. The San Antonio will be shock hardened and equipped with the latest in firefighting and damage control equipment. Those designing this class of ship certainly did not overlook quality of life factors for Sailors and Marines, both male and female. Living spaces have adjacent sanitary facilities, nearby lounges and the only difference between crew and troop berthing will be the troop armories located close by. New bunks, the sit-up berths, improve the old style "bunk beds" by allowing the occupant to sit up and use a portable reading and writing surface. There will be a single, consolidated galley aboard the ship, so that officers and enlisted personnel will enjoy the same meals. Automated computer workstations will make ship navigation easier and enable the ship's engineers to more effectively control the diesel power plant. The Ship Wide Area Network (SWAN) connects the various ship systems, while providing Internet and e-mail services. The SWAN also serves as the access to training courses, from professional Navy courses to college classes through teleconferencing means. The 21st Century Sailor or Marine embarked aboard USS San Antonio (and the 11 ships of her class that will follow) will use computers every day. The ship is named for the city of San Antonio, Texas, thus keeping alive the tradition of naming ships after American cities. It will be the first U.S. Navy ship so named, creating a bond between city and ship that will endure throughout the ship's projected 40-year lifetime. San Antonio city and community leaders, recognizing the importance of this bond, established the USS San Antonio Commissioning Committee and designated Mr. Richard M. Kleberg, III as the Commissioning Committee Chairperson. The LPD-17 Program, managed by the Program Executive Office (PEO) for Expeditionary Warfare (PMS 317), began transitioning from detail design to lead ship production in the year 2000. Supported by the Supervisor of Shipbuilding (SUPSHIP)--New Orleans, construction of San Antonio began in August 2000, followed by the keel laying ceremony last December. The first two ships of the class, San Antonio (LPD 17) and New Orleans (LPD 18), are being built by Northrop Grumman's Litton-Avondale shipyard in New Orleans, LA. The PEO is responsible for all aspects of life cycle management for its assigned programs. The Naval Sea Systems Command (NAVSEA), headquartered at the Washington Navy Yard, provides the PEOs with total ship system engineering, establishes and coordinates technical policy and procedures, and delivers integrated logistics support. Source: NAVSEA


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iAd Producer – How to open YT links in Safari?
I have an error with the iAd browser that does not allow YouTube videos to play. Apple's workaround is to implement a
javascript call on all YouTube-link
button taps that launch the link in the Safari web browser instead of the in-app browser using
window.location in the
Code implemented:
window.location = "http://…";
But still not launching in the Safari web browser.
Main Code:
this.onViewActivate = function (event) {
window.location = "https://www.youtube.com/watch?v=eM8Wpq-oD5o&index=3&list=PLbh4x6U6o9F6sLbGWaAtgdvEmceJLYgwO";


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David Warner started this year on a high note. He followed his record breaking ton by a fifty that is the fastest ever in test by any Aussie. On the fourth day of Pink Test he also became the second fastest in the history after Misbah's 21-ball half century against Australia in 2014.
After rain washed out first session, Australia didn't enforce the follow on and asked their openers to bat again. David Warner came with different ideas. In the process he smashed Yasir Shah for 21 runs in an over with two sixes and two fours in a row and raced to his fifty. He beat Bruce Yardley's record, who scored his fifty in 29 balls against West Indies in 1978.During this sparkling knock of 55 off 27 balls, he smashed 8 fours and 3 sixes with the strike rate of 203.70!


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Stock Graphic >> Pattern - 10 Chevron Seamless Web Patterns 164522 by chicwebco @ CreativeMarket
File Size: 21.57 MB; Tileable: Yes.
Chic Web Co. Seamless Web Pattern and Hi-Resolution Digital Paper Set including high resolution files for your printing needs as well as 72dpi web resolution files ideal for your web design or blog design project.
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