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Stay alive and drive 25... After November 7, this is going to be the new speed limit in New York City.
Mike Bloomberg banned smoking and trans fats, now Bill de Blasio wants NYC to be known as slow city.
Happy trails, New Yorkers: Roy Rogers and Dale Evans - Happy Trails: http://youtu.be/HMqXdrUjEe8 via @YouTube
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Anyone seeking permission to use a front page must credit the Newseum and contact the newspaper directly for permission. U.S. copyright laws apply.


text:
|Search Product Inventory
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Sepulveda Wine has resources for recent and vintage wines, ports, and spirits. Please contact us with your requests.
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subset: commoncrawl


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Just a couple months ago, Virginia Tech went to Monroe (Ga.) Monroe Area in pursuit of athlete Demontevious Smith. The Hokies have returned to the school in recent weeks with an offer to their next...
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Welcome Sixth Grade Team Home Page
What's Up? Camp OHIO!
Leave for Camp Ohio, Tuesday, May 20---back home Friday, May 23!
Homework Hotline: Monday, May 19, 2014
Language Arts: NO HW. Summer reading suggestions on itslearning!
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Social Studies: NO HW
Need help with homework, studying for a summative, reviewing concepts?
ZAP! Is here for you!
EIMS Library, 3:00-4:15
Join us next year!
To learn more about each of the 6th grade classes click on the image below:
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Suggested Links for Looking Good and Sounding Smart!
Typing Skills
Free Rice: Choose skills to strengthen while helping others!
Brain POP
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Password: brainpop
Progress Book


text:
PUPILS travelled the world to experience a feast of festivals from cultures of all kinds - without even leaving their school.
Youngsters at Owler Brook Primary in Fir Vale staged a festive show with a difference for mums, dads and relatives.
Festivals and Celebrations from Around the World was put together by staff and children to reflect the multicultural nature of the inner city Sheffield school.
Beginning with the famous strains of Walking in the Air, the pupils took to the skies like the Snowman to see how different peoples mark their own special occasions. First stop was Pakistan where Eid celebrations were well under way following the conclusion of Ramadan.
Then next it was off to the USA to see how a turkey dinner is an essential part of Thanksgiving.
The children showed how Christmas is celebrated in Slovakia - as the school has had a recent influx of pupils from the central European country - with plenty of good food and plenty of dancing.
Other ports of call were Africa, Spain and finally back to England to enjoy a traditional Christmas with carols, presents and crackers.
Headteacher Sue Bridges said all 150 children in the school played a part in the show, whether on stage or in the choir.
"We had lots of colourful costumes representing the different festivals and the show was created to include all the 11 different nationalities we have in school," she said.
"The school hall was packed with parents - in fact it was standing room only.
"We have special shows at Christmas and at the end of the summer term. Originally they just featured songs but they've now grown into something much bigger," she added.


text:
BC-IL--Chicago-Trauma Center/135
Eds: APNewsNow.
University of Chicago Medicine seeks OK for $269M expansion
CHICAGO (AP) — University of Chicago Medicine has submitted to state regulators a $269 million expansion proposal that includes an adult trauma center.
The health system announced Thursday it's asking regulators to approve the addition of 188 inpatient beds. Hospital officials say that would return the hospital to roughly its size in the late 1970s.
The plan includes turning Mitchell Hospital into a cancer center.
University of Chicago Medical Center President Sharon O'Keefe says the plan would reduce disparities in access to critical care on the South Side and address "severe capacity constraints" at the hospital. She says the hospital had to turn away patients on 310 days last year.
The South Side hasn't had adult trauma care since 1991 when the Michael Reese Hospital in the Bronzeville neighborhood closed its trauma center.
Copyright 2016 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


text:
Director, co-producer of Tap Out
It does not surprise me at all that Vikki Matsis wrote a revealing book about a secretive industry. That's Vikki - truthful, upfront, a what-you-see-is-what-you-get person. Vikki is a no guile girl, and you've got to love her for it.
Will Moredock stuck his neck out for justice and equality week after week for ten years, and week after week, he took the slings and arrows of anonymous haters. Unlike his mysterious detractors, he boldly signed his real name to his often hotly debated columns. That's a lesson in courage for all of us. Good luck to you, Will and thank you.
The film will be shown at 5:30 on Thursday at the School of Education's Alumni Center. The entrance is on St. Philip Street between Wentworth and Liberty Streets. There is a workshop on Saturday at the same location and bus tour on Sunday.
Good Column, Will and congratulations to Kerry Taylor and The Citadel for creating these important oral histories with the Smithsonian.
I first met Mr. Bill Saunders ten years ago when I interviewed him for a documentary I was making titled, Where Do We Go From Here. I found Bill to be a serious man with flinty courage and an unlikely intellectual from rural Johns Island.
I had been inspired by Lucy Massie Phenix's 1985 documentary, You Got To Move. It focused on Highlander School alumni who have been leading the fights for civil and labor rights. One of whom was Bill Saunders.
In a perfect conclusion, I recently got a call from Lucy Massie Phenix. She asked me to film an interview for the bonus tracks of the 25th anniversary edition of You Got To Move with none other than Bill Saunders.
This Oct 18th the anniversary edition of You Got To Move will be released from Milestone Films. http://www.yougottomove.com
Come see Tap Out - the controversial documentary about water on Saturday, May 21st at 5:00 at the American Theater on King Street.


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Despite the rain and fog, the South China Downhill Clinic went off without a hitch! 36 riders showed up to learn how to effectively out their board sideways to burn speed and stay in their lanes. Big thanks to #OrangatangAmbassador @hazzaclarke_hlss...


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Yummy, yummy oldschool diner foods. All cooked very well. Very friendly staff, always smiling and they check on you constantly.
1 - 10 of 26 reviews
Yummy, yummy oldschool diner foods. All cooked very well. Very friendly staff, always smiling and they check on you constantly.
This place was one of my favorite places to eat until they moved to the court square. They charged too much after the move and couldn't survive. I wish they would have stayed in the same place.
The food is so close to my Mom's it brings back memories, friendly staff with clean bathrooms. xxxxx
Anytime you go to Mary's, you can count on feeling like one of the family. The food is awesome, best chicken tenders in town and you can get breakfast, lunch or dinner any time of the day...
Can't ask for better breakfast and the waitress we had was the friendliest person we met that day. Lots of good food for a small price
Average food but still a good spot to eat if you like some home cooking. One of the few places left that still has a smoking section. Open all night and serve both breakfast and lunch anytime. Prices are reasonable. Most meals under $10.00 including...More
I love this place.. while it may not look like a 5 star restaurant the food most definitely is. The prices are excellent. The staff friendly and a nice change to finally find a restaurant that allows smoking.
Been here a couple of times because others asked us to join them. Thought it would be a nice local diner type place. It was a Chinese restaurant that they purchased and moved into. Some of the decor is still there the res is a...More
We were passing through and read a couple of reviews, sounded ok to wait a storm out and eat. We walked into what appeared to be a basic building, but on the inside the floor tile was coming up walls were peeling, every seat was...More
My husband and I walked into Mary's Kitchen as it was recommended by a friend and as soon as we walked into the restaurant, we were smacked in the face with a greasy smell. We tend to try to eat without the grease so that...More


text: Efficient message passing scheduling for terminated LDPC convolutional codesMichael Lentmaier, Maria Mellado Prenda, Gerhard Fettweis2011 IEEE International Symposium on Information…2011Message passing schedules that reduce the decoding complexity of terminated LDPC convolutional code ensembles are analyzed. Considering the AWGN channel, various schedules are compared by means of density evolution. The results of the analysis together with computer simulations for some (3,6)-regular codes confirm that sliding window decoding is an… (More)


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Businesses are formed in manyways, and we have come to know those varying abbreviations (S-Corp, C-Corp,LLC, LLP, LP, LTD, and so on and so forth) that represent each varyingbusiness. But when it comes to passing on your business, there isanother acronym to consider: the ESOP.
So, what is an ESOP, what can itdo, and is it right for your business?
ESOPs, or Employee StockOwnership Plans, are a tricky breed. Essentially, an ESOP is a tool recentlyhighlighted by Congress and featured by TheWall Street Journal in an article titled "Founders Cash Out, but Do Workers Gain?â€Planning to exit a business is all about doing one of two things; eitherrestructuring the business or selling it outright. With an ESOP you accomplishboth goals and build the company around the very employees that compose thecompany in the first place.
Rather than going out andhunting for a buyer, the employees become vested in the stock ownership oftheir own company. In turn, the ownership stake simultaneously becomes aretirement asset while the ownership of the founder is bought out.
Now, if you are already familiarwith this approach, it may be worth reading the original article since thereare certain limitations affecting the employees-turned-owners. The articlegives examples of how an ESOP can work a win-win for all concerned under theright circumstances. These examples include Bob's Red Mill, for example, or,from a different industry, Manson Construction Co.
ESOPS have been a powerful toolin an otherwise soft market for business transfers. Accordingly, ESOPS areworth a good look, and then even a second look, as a unique and proven businesssuccession strategy.
At IdahoEstate Planning we are the expertsyou need to know and trust. Work with us and we'll put together a plan thatworks for you and your loved ones. Remember, goodplanning is no accident.
At Idaho Estate Planning, we are dedicated to helping you and your family secure peace of mind and a sure foundation for generations.


text:
FKD Bearing Press
Free Shipping. No Minimums. United States customers only.
You can return an item up to 30 days after you purchased it. Products must be in new and unused condition. See Details.
As invaluable as an $8.00 skate tool is, spending the bucks for a real bearing tool is well worth it. Every good shop has one of these things fastened to a bench, but dont think of it as a luxury only for skate shops. If you frequently set up new decks or replace your bearings frequently, this tool will let you effortlessly do it right EVERY time.
How many times have you set a bearing by pressing it into place with a cheap skate tool? And how many times did the wheel wobble slightly until you put some more weight into it? Several, if youre new to the technique. If youre replacing bearings, how many skate tools have a reliable (aka - useable) bearing remover? Damn few. And who hasnt ruined a wheel trying the ever-popular hammer & screwdriver combo technique?
Setting bearings is a snap with FKDs press. Simply slide on the two bearings, one wheel and give the handle a firm squeeze. Done. Perfect rotation, no wobbles and no broken parts. Removing a bearing is just as easy - just use the other end of the press. Hook the bearing on the end, pull the handle and presto - your old bearings are out.
Owning a bearing press is more than just a cool-factor. Its about using the right tool for the job. On the other hand, your cool-factor will definitely rise when your pals see this baby bolted to your bench. It give off the notion of "I know what the hell Im doing" - even if ya dont.
PLEASE NOTE: THIS BEARING PRESS WILL NOT ACCOMODATE A 7mm BEARING. It only takes a standard 8mm skate bearing.
THIS BEARING PRESS DOES NOT ACCOMODATE ROLLER BLADE WHEELS OR INLINE WHEELS AND CERTAIN WHEELS THAT ARE BIGGER THAN A 65mm size.
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99.9% of all orders ship out within one business day! In fact, over 90% of orders placed Monday-Friday before 3pm EST ship out the same day. These are not just pretty words. We stand behind this commitment with our Fast Shipping Guarantee.
Here's the guarantee: if we don't ship out within one business day, we will give you 10% off your order. See here for details.
The readers of Concrete Wave, the leading longboard publication, generously named Daddies the best online longboard shop of 2012. And we didn't even have to bribe them!
Daddies has a few other feathers in its cap. We have been an Inc. 5000 Fastest Growing Company in the United States for the last three years and a Portland Business Journal Top 100 Fastest Growing Private Company for the past five years (our home is in Portland, Oregon). Our goal with all of this fast growth is clear: world domination! Well, that and being in the Guinness Book of World Records for the longest fingernails.
We price match. And we'll give you 5% off for doing it.
We want to give you the best prices and best customer service. We know that nobody ever, ever, ever beats our customer service. But, we're also going to take care of you if someone dares to try and beat us on price! See here for details.
This month, all orders over $19.95 get the newest sticker of the month. When robots take over the world, it will surely be more or less like when humans did: Some will be jerks, some will gather all the power, and some will just want to shred. Ted Cocuzza envisions a world where robots still have the freedom to throw a steezy layback grind on a DIY spot when they feel the need.
As always, every order will come with two free classic Daddies stickers at no cost. We know... we're sweet.


text:
Move the guide to refine
6 hotels found in Naengch'ŏl-li
Result 1-6
Daegu, 688-1 Bongduk-Dong Nam-Gu
7.8 km
Daegu, 13, Icheon-ro, Nam-gu
Daegu, 305, Dongdaegu-ro, Suseong-gu
8.6 km
Daegu, 563-1, Beumeo-dong,
Daegu, 563-1 Bumuhdong Soosungku Daegu
Daegu, 148, Hyeonchung-ro
9.1 km
After entering a search request the hotel room prices and availability are being downloaded real-time from approximately 30 hotel- and booking websites. If it is unexpectedly not possible to request the hotel room prices and availability from one or a few providers, or if one provider does not transmit the information to LookingforBooking after entering a search request, only the prices and availability from available providers are being displayed. If you want to see the full picture of all hotels at LookingforBooking, you should search without a date. Then you will be able to compare all hotels on their location and facilities.


text: Ayatollah Khamenei: Has not the time come yet for the West to apologize? Dec 16, 2015 Print Full text of Ayatollah Khamenei's 2nd letter to the youth in Western countries Related Today terrorism is our common worry Good terrorist, bad terrorist! Who is a bigger criminal? ISIS or Israel? More from Khamenei.ir A comparative look at treatment of minorities: Islam vs. West Let us unite to help Gaza and overcome Zionism: Ayatollah Khamenei Everyone should openly support people of Yemen, Bahrain and Kashmir Comments Timothy Jagrossi 2017-02-05 14:37 I think we (collectively) are beginning to realise that military intervention abroad does nothing positive. Rather than trying to force other nations to adhere to our way of life, we should be respecting their customs and know that if it were wrong and needed change, it would naturally correct itself over time, just as society has always worked. Many here would apologise to Muslim world, even if political figures do not. But whose apology is more valuable? Comment


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Volume 13,Number 3, June 2016
Special issue on the Neural Coding 2014 workshop
Pages : i - i
Susanne Ditlevsen and Petr Lansky
Full Text
Related Articles
The effect of positive interspike interval correlations on neuronal information transmission
Pages : 461 - 481
Sven Blankenburg and Benjamin Lindner
Full Text
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A leaky integrate-and-fire model with adaptation for the generation of a spike train
Pages : 483 - 493
Aniello Buonocore, Luigia Caputo, Enrica Pirozzi and Maria Francesca Carfora
Successive spike times predicted by a stochastic neuronal model with a variable input signal
Pages : 495 - 507
Giuseppe D'Onofrio and Enrica Pirozzi
Efficient information transfer by Poisson neurons
Pages : 509 - 520
Lubomir Kostal and Shigeru Shinomoto
Integrator or coincidence detector --- what shapes the relation of stimulus synchrony and the operational mode of a neuron?
Pages : 521 - 535
Achilleas Koutsou, Jacob Kanev, Maria Economidou and Chris Christodoulou
Fluctuation scaling in neural spike trains
Pages : 537 - 550
Shinsuke Koyama and Ryota Kobayashi
Effect of spontaneous activity on stimulus detection in a simple neuronal model
Pages : 551 - 568
Marie Levakova
A model based rule for selecting spiking thresholds in neuron models
Pages : 569 - 578
Frederik Riis Mikkelsen
On the properties of input-to-output transformations in neuronal networks
Pages : 579 - 596
Andrey Olypher and Jean Vaillant
A new firing paradigm for integrate and fire stochastic neuronal models
Pages : 597 - 611
Roberta Sirovich and Luisa Testa
Approximation of the first passage time density of a Wiener process to an exponentially decaying boundary by two-piecewise linear threshold. Application to neuronal spiking activity
Pages : 613 - 629
Massimiliano Tamborrino


text:
September 23, 2012 BY Aaron Hope
We've seen quite a bit of Hyperfuse in play with Nike Sportswear's recent Air Max 90 releases, but this new drop for ladies proves the essential style won't be replaced any time soon. The women's Nike Air Max 90 pictured above is a bit like a recent HYP release in that it notably features orange and blue elements that connect to one of the National Football League's franchises. That upcoming pair has a Chicago Bears look to it, but women won't have to wait to get their hands on this glossily Swooshed Miami Dolphins lookalike, as it's available now at NSW retailers like Titolo.
Nike WMNS Air Max 90
Neutral Grey/Shaded Blue-Mandarin-White
Filed under: Air Max 90 Just Released Nike Air Max Nike Retro Running
Tags: Nike Air Max 90


text:
Orkney Skara Brae Thos. Kent's series RP npu c.1910 exc cond
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- Sold Date:
- Source: eBay UK
Antique original real photographic postcard .Title : Posted : Photographer : Printer : Publisher / Retailer : Thos. Kent's series Condition : as per scan; excellent Comments : Please check scans carefully prior to bidding. Most postcards on this site are over a century old and as such often exhibit minor surface,edge and corner damage which may not always be apparent from the scan. I will try and draw attention to significant imperfections which may not be immediately obvious. Images maybe scanned at low resolution; o n receipt they should appear as good, if not better than, the screen image. Where present the security overlay 'bonus-henricus' does not appear on the purchased item


text:
|Publication number
|Publication type
|Application number
|Publication date
|Jun 1, 2010
|Filing date
|Jun 27, 2007
|Priority date
|Jun 27, 2007
|Fee status
|Also published as
|Publication number
|Timothy Kennedy, Tami O'Connell
|Original Assignee
|The Clorox Company
|Export Citation
|BiBTeX, EndNote, RefMan
|Patent Citations (45), Non-Patent Citations (2), Referenced by (4), Classifications (15), Legal Events (2)
|External Links: USPTO, USPTO Assignment, Espacenet
1. Field of the Invention
This invention relates to liquid pump dispensers for use with substrates such as paper towels, wipes, woven or nonwoven dishcloths, and sponges. More specifically the present invention relates to a dispensing package having a suction-flow liquid draw-back subsystem from a dispensing package actuator to the dispensing package liquid distribution subsystem used to distribute liquid from a dispensing package container to the actuator.
2. Description of the Related Art
Consumers have traditionally applied cleaning and disinfecting compositions with a dispenser, sometimes called a dispensing package. For example, in a cleaning process, a consumer applied the composition from a trigger spray bottle dispenser by spraying the composition on a surface and wiping it with a paper towel. Alternatively, the composition in a pour or pump-out bottle dispenser was added to a sponge, activated with water, and wiped on and rinsed off the surface with the sponge. These procedures and cleaning systems are inefficient because the consumer must go through several cleaning steps.
As an alternative to spray, pump-out, and pour dispensed cleaning systems, wet disinfectant or cleaning wipes, such as described in U.S. Pat. No. 6,716,805 to Sherry et al., are becoming increasingly popular for their convenience in combining a nonwoven, disposable substrate with a disinfecting or cleaning composition. Soap-loaded disposable dish cloths, as described in U.S. Pat. No. 6,652,869 to Suazon et al., are also popular for their convenience. These products combine the cleaning composition and the cleaning substrate in one cleaning system so that the consumer can perform the cleaning task with one hand and with one product. However, these systems have some drawbacks such as requiring water activation of a dry substrate or requiring a sealed packaging for a wet substrate.
Current dispensing packages, however, are not adequate for one hand application of cleaning and disinfecting compositions to cleaning substrates such as paper towels. Dispensing packages such as trigger sprayers or pump dispensers generally require one hand to hold and activate the dispenser and one hand to hold the cleaning substrates. Existing pump-up dispensers that can be ergonomically operated with the same hand that holds the cleaning substrate have small actuators that require the hand and substrate to be contracted into a ball in order to activate the dispenser. To overcome the problem that existing pump-up dispensers having small actuators that require the hand and substrate to be contracted into a ball in order to activate the dispenser is address in co-owned patent application Ser. No. 11/609,740 now U.S. App. 2008/0138143; Ser. No. 11/609,749 now U.S. App. 2008/0138144, Ser. No. 11/609,761 now U.S. App. 2008/0135581, and Ser. No. 11/621,235 now U.S. App. 2008/0166174 each of which is incorporated by reference in their entirety. These co-owned patent applications describe dispensing package liquid distribution subsystems that distribute a liquid at the entire top surface area of a large, hand-sized actuator so that the hand and substrate need not be contracted into a ball in order to operated the dispensing package.
Further, while gravity-flow liquid drain-back features are very common for bottle/spout systems for laundry aisle products, existing pump-up dispensing packages do not provide a drain-back subsystem that returns excess dispensed cleaning compositions not absorbed by the cleaning substrate. Some pump mechanisms and dispensers specifically prevent liquid from draining back into the liquid container of the dispensing package or from being drawn back into the liquid distribution subsystem of the dispensing package. This may be important for disinfecting or registered cleaning compositions.
However, it would often be desirable with other compositions or liquids, to collect excess dispensed product, not fully absorbed by the substrate at the actuator top surface, and return it to the composition product container of the dispensing package. Where product drain-back into the container would not compromise the integrity of the product, this excess liquid collection and return feature would aid in the use, appearance, and efficiency of the dispensing package and would help prevent product drooling. Preventing product drooling or pooling on a dispenser surface would be an aesthetic benefit to the consumer.
Embodiments of a gravity-flow liquid drain-back subsystem are disclosed in co-owned patent application Ser. No. 11/767,646 now U.S. App. 2008/0314925, which is incorporated by reference in its entirety. The gravity-flow liquid drain-back system returns excess liquid not absorb by the substrate during actuation of a pump-up dispensing package to the container from which the liquid product is dispensed. A drain-back pathway, separate from the liquid distribution system pathway, is utilized to drain excess liquid back to the dispensing package container. It would be desirable to provide an excess liquid collection subsystem for a dispensing package which avoids the separate return pathway of the gravity-flow liquid drain-back subsystem.
To overcome these problems of prior art cleaning systems, the dispensing package embodiments of the present invention are designed to provide a dispensing package that allows a consumer to conveniently apply a liquid cleaning composition from a container to a substrate with one hand and in a controlled manner. Further, the dispensing package embodiments of the present invention are designed to provide a dispensing package that allows for the collection and return of excess liquid cleaning composition not absorbed by the substrate without the need for a liquid pathway separate from the liquid pathway used to apply the liquid cleaning composition to the substrate.
Embodiments of the present invention provide a liquid dispensing package that includes a container adapted to contain a liquid and an actuator having an actuator top with at least one discharge orifice therethrough. An actuator top surface of the actuator top, is in fluid communication with the container through the one or more discharge orifices to permit flow of liquid from the container to the actuator top surface upon reciprocation of the actuator. Further, the at least one discharge orifice is in fluid communication with a suction device to permit flow of liquid from the top surface of the actuator through the at least one discharge orifice upon reciprocation of the actuator.
In accordance with an object of the present invention and those that will be mentioned and will become apparent below, one aspect of the present invention is a dispensing package that includes a hand operated liquid transport assembly having a pressure component and a suction component and coupled to the actuator, a liquid distribution subsystem comprising a discharge tube from the liquid transport assembly, wherein depression of the actuator causes liquid to travel through the discharge tube to the actuator top surface. The liquid distribution subsystem delivers liquid to an area of the actuator top surface greater than the circumferential area of the discharge tube
The liquid distribution subsystem of the dispensing package may include a manifold type distribution subsystem, a spray type distribution subsystem, or a surface distribution channel type distribution subsystem. Various liquid distribution pathways from the container to the actuator top surface are utilized.
Another aspect of the present invention a dispensing package that includes a suction device, coupled to the actuator, a liquid draw-back subsystem wherein return of the actuator causes liquid to flow from the actuator top surface to the liquid distribution system.
The suction-flow liquid draw-back subsystem of the dispensing package may include a piston type draw-back subsystems, a bellows type draw-back subsystem, or a flexible membrane type draw-back subsystem. The liquid drawback pathway from the actuator top surface is a portion of the liquid distribution pathway utilized to deliver liquid to the actuator top surface.
While this invention is susceptible of embodiment in many different forms, this specification and the accompanying drawings disclose only some specific forms as examples of the invention. The invention is not intended to be limited to the embodiments so described. It is also to be understood that the terminology used herein is for the purpose of describing particular embodiments of the invention only, and is not intended to limit the scope of the invention in any manner. The scope of the invention is pointed out in the appended claims.
For ease of description, the components of this invention and the container employed with the components of this invention are described in the normal (upright) operating position, and terms such as upper, lower, horizontal, etc., are used with reference to this position. It will be understood, however, that the components embodying this invention may be manufactured, stored, transported, used, and sold in an orientation other than the position described.
Figures illustrating the components of this invention and the container show some conventional mechanical elements that are known and that will be recognized by one skilled in the art. The detailed descriptions of such elements are not necessary to an understanding of the invention, and accordingly, are herein presented only to the degree necessary to facilitate an understanding of the novel features of the present invention.
All publications, patents and patent applications cited herein, whether supra or infra, are hereby incorporated by reference in their entirety to the same extent as if each individual publication, patent or patent application was specifically and individually indicated to be incorporated by reference.
As used herein and in the claims, the term "comprising" is inclusive or open-ended and does not exclude additional unrecited elements, compositional components, or method steps. Accordingly, the term "comprising" encompasses the more restrictive terms "consisting essentially of" and "consisting of".
It must be noted that, as used in this specification and the appended claims, the singular forms "a," "an" and "the" include plural referents unless the content clearly dictates otherwise. Thus, for example, reference to a "surfactant" includes two or more such surfactants.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which the invention pertains. Although a number of methods and materials similar or equivalent to those described herein can be used in the practice of the present invention, the preferred materials and methods are described herein.
In the application, effective amounts are generally those amounts listed as the ranges or levels of ingredients in the descriptions, which follow hereto. All percentages, ratios and proportions are by weight, and all temperatures are in degrees Celsius (� C.), unless otherwise specified. All measurements are in SI units, unless otherwise specified. Unless otherwise stated, amounts listed in percentage ("%'s") are in weight percent (based on 100% active) of the cleaning composition alone. It should be understood that every limit given throughout this specification will include every lower, or higher limit, as the case may be, as if such lower or higher limit was expressly written herein. Every range given throughout this specification will include every narrower range that falls within such broader range, as if such narrower ranges were all expressly written herein.
The term "surfactant", as used herein, is meant to mean and include a substance or compound that reduces surface tension when dissolved in water or water solutions, or that reduces interfacial tension between two liquids, or between a liquid and a solid. The term "surfactant" thus includes anionic, nonionic, cationic and/or amphoteric agents.
The composition can be used as a disinfectant, sanitizer, and/or sterilizer. As used herein, the term "disinfect" shall mean the elimination of many or all pathogenic microorganisms on surfaces with the exception of bacterial endospores. As used herein, the term "sanitize" shall mean the reduction of contaminants in the inanimate environment to levels considered safe according to public health ordinance, or that reduces the bacterial population by significant numbers where public health requirements have not been established. An at least 99% reduction in bacterial population within a 24 hour time period is deemed "significant." As used herein, the term "sterilize" shall mean the complete elimination or destruction of all forms of microbial life and which is authorized under the applicable regulatory laws to make legal claims as a "Sterilant" or to have sterilizing properties or qualities.
As used herein, the term "polymer" generally includes, but is not limited to, homopolymers, copolymers, such as for example, block, graft, random and alternating copolymers, terpolymers, etc. and blends and modifications thereof. Furthermore, unless otherwise specifically limited, the term "polymer" shall include all possible geometrical configurations of the molecule. These configurations include, but are not limited to isotactic, syndiotactic and random symmetries.
The term "plastic" is defined herein as any polymeric material that is capable of being shaped or molded, with or without the application of heat. Usually plastics are a homo-polymer or co-polymer that of high molecular weight. Plastics fitting this definition include, but are not limited to, polyolefins, polyesters, nylon, vinyl, acrylic, polycarbonates, polystyrene, and polyurethane.
Dispensing Package
A part of the liquid transport assembly 26 may extend into the container opening or mouth 30. The bottom end of the liquid transport assembly 26 is attached to a conventional dip tube 28, and the upper end of the liquid transport assembly projects above the container neck 23. The liquid transport assembly 26 includes an outwardly projecting flange 36 for supporting the liquid transport assembly 26 on the container neck 23 over a conventional sealing gasket 38 which is typically employed between the liquid transport assembly flange 36 and container neck 23. Other sealing designs such as plug seals can be used in place of a gasket. The hollow stem or discharge tube 40 establishes communication between a pump chamber 33 (
The actuator 24 has a hand-and-substrate engageable region and can be depressed by the user's hand containing a substrate, such as a sponge, to move the discharge tube 40 downwardly in the liquid transport assembly 26 to dispense liquid from the liquid transport assembly 26. The liquid is pressurized in the liquid transport assembly chamber 33 (
It will be appreciated that the particular design of the liquid transport assembly 26 may be of any suitable design for pumping a product from the container 22 (with or without a dip tube 28) and out through the discharge tube 40. The detailed design and construction of the liquid transport assembly 26 per se forms no part of the present invention except to the extent that the liquid transport assembly 26 is adapted to be suitably coupled and held on the container 22 with a suitable mounting system.
As described in detail below with reference to
The container 22 can have a variety of shapes. The container can be round or oval or rectangular with rounded corners as shown in
The ergonomic shape of the actuator 24 makes the actuator easy to be a liquid transport assembly with a substrate such as paper towel or sponge, and to operate using one hand. One measure of the actuator shape is a vertical projection 71 (
The actuator top 72 can have a concave shape that is round, oval, a rectangular with rounded corners as shown in (
The actuator can individually be adapted to the respective requirements with regard to the direction of the discharge orifice as well as with regard to the use of opening valves. The actuator is not limited to having a discharge orifice 25 which moves together with the actuator, but it may also comprise an actuator of the type having a stationary discharge orifice 25, as shown in
Actuator Discharge Orifices
As noted above, the dispensing package can have one or more openings or discharge orifices 25 situated on the actuator 24 (for example
Liquid Transport Assembly
For the purpose of the discussion below liquid pumps may be described as "pressure" components or "suction" components. Those of skill in the art recognize that pumps are both pressure generating devices, at their outlet, and suction generating devices, at their inlet. The liquid pumps described are characterized as pressure or suction components based on their primary use in the dispensing packages of the present invention.
Referring to
Turning now to the suction component 55 of the liquid transport assembly 25, the suction component 55 operates as a conventional bellows pump. The primary use of the suction component 55 is to draw-back liquid into discharge orifices of an actuator top surface such as discharge orifices 25 and actuator top surface 74 of the dispensing package shown in
Upon application of a downwardly directed force on the actuator 24 (
Liquid Distribution Subsystem and Liquid Draw-back Subsystem
The actuator 24 defines a discharge passage through which the product from the stem or discharge tube 40 is discharged. The actuator 24 has a hand-and-substrate engageable region and can be depressed by the user's hand containing a substrate, such as a sponge, to move the discharge tube 40 downwardly in the liquid transport assembly 26 to dispense liquid from the liquid transport assembly 26. The liquid is pressurized in the pump chamber 33 and exits from the actuator discharge orifices 25 (
When the actuator discharge covers a large area, it may be desirable to have a liquid distribution subsystem to deliver the liquid from the hollow discharge tube 40 delivered from container 22 by the liquid transport assembly 26 to the discharge orifices 25. As described in more detail below with reference to
Further, it may also be desirable to provide a suction-flow liquid draw-back subsystem to return excess liquid not absorbed on a substrate to a portion of the distribution subsystem. As, also described in more detail below with reference to
In one embodiment the suction-flow liquid draw-back subsystem includes the at least one distribution orifice 25 of the liquid distribution system on the actuator top surface 74 that are in fluid communication the distribution tube 40. While liquid is permitted to flow from the container 22 to the actuator top surface 74 upon application of downwardly directed force on the actuator 24, liquid is permit flow from the actuator top surface 74 through the discharge orifices 25 upon released of downward force and resilient spring return of the actuator 24 distributed by the liquid distribution subsystem when actuator 24 is pressed downwardly. The distribution orifices 25 are in fluid communication with the suction component 55 to provide draw-back suction upon resilient spring return of the actuator 24. Thus the distribution orifices 25 both deliver liquid to the actuator top surface 74 and draw back liquid from the actuator top surface 74 along the same pathway upon full reciprocation of actuator 24.
Operation of the Dispensing Package
More particularly,
Liquid transport assembly 26 includes a hollow dip tube 28 adapted to transport a liquid. An actuator 24, coupled to the liquid transport assembly 26, may be manually reciprocated by a user of dispensing package 20 to move liquid (not shown) contained in container 22 through the dip tube 28 and the discharge channels 45 to the an actuator top 72 of the actuator 24 having an actuator top surface 74 with discharge orifices 25 that terminate the discharge channels 45 (
When a user pushes actuator 24 down, discharge tube 40 to which actuator 24 is coupled also moves down and liquid is initially discharged from the suction component 55 through discharge tube 40 of the transport assembly 26 shown in
With further downward movement of the actuator 24, the bellow base 63 moves downward, and the interconnect tube 58 to which it is coupled likewise moves downward. As noted above, the interconnect tube 58 of the pressure component 54 is coupled at one to the piston head 42 and at it other end to the bellows base 63. Thus, the downward movement of interconnect tube 58 causes the pressure component 54 to operate as a piston pump as described above thereby forcing liquid through the interconnect tube 58, past outlet check ball 65 through suction component 55 and out through discharged tube 40 to distribution orifices 25.
After the actuator 24 is released by the user, suction component 55 expands as described above and draws-back any excess liquid on the actuator top surface 74 of the actuator top 72 into the distribution orifices 25, discharge tube 40, and the suction component 55 of the liquid transport assembly 26. At the same time the resiliently compressed pump coil spring 56 of the pressure component 54 biases pump piston 39 upwardly thereby drawing liquid 21 from the container 22 (
Advantageously, by selection of suitable the various resilient elements such as coil spring or bellows sidewall, the suction components 55 of
Discharge channels 45 may fluidly connect the discharge tube 40 with corresponding discharge orifices 43 terminating respective discharge channels 45. The discharge orifices 43 or 25 may span a significant portion of the actuator top 72, thereby providing liquid flow to an area of the actuator top 72 larger than the diameter of the discharge tube 40. Typically, the discharge orifices 43 may span between about 60 to about 95% of the length 78 of the top surface 72.
The liquid distribution subsystem of
The liquid distribution subsystem of
The liquid distribution subsystem of
A liquid transport assembly 26 may be actuated by depressing the actuator 84. A stem 89 may connect the actuator 84 with the liquid transport assembly 26. The stem 89 may be connected to a liquid transport assembly piston (not shown in
The liquid distribution subsystem of
The liquid distribution subsystem of
The liquid distribution subsystem of
The liquid distribution subsystem of
The liquid distribution subsystem of
The liquid distribution subsystem of
Additional Functional Features
In one embodiment, additional functional characteristics designed into the container base to offer stability and to encourage consumers to leave the product out on their counters so it is easily accessible. In one embodiment, a means is provided to allow the container to attach to the counter. One such example is a suction cup or other device on the bottom of the container. In addition to standing upright, for example on a counter-top, the dispensing package may be attached to a surface and used with the dispensing package discharge orifices on the bottom, for example attached to the underside of kitchen cabinets.
In one embodiment, the exterior of the dispensing package is resistant to microorganisms. Various anti-microbial agents known in the art can be applied the exterior surface of the dispensing package to impart virucidal, bacterial, and/or germicidal properties thereto. The anti-microbial agent can comprise up to 100% of the surface area of the exterior surface of the dispenser, and in some embodiments, between about 10% to about 80%. The anti-microbial agent can include silver ions. In certain embodiments, a silver-zeolite complex can be utilized to provide controlled release of the anti-microbial agent. One commercially available example of such a time-release anti-microbial agent is sold as a fabric by HEALTH SHIELD� under the name GUARDTEX�, and is constructed from polyester and rayon and contains a silver-zeolite complex. Other suitable silver-containing microbial agents are disclosed in Japanese Unexamined Patent No. JP 10/259325. Moreover, in addition to silver-zeolites, other metal-containing inorganic additives can also be used in the present invention. Examples of such additives include, but are not limited to, copper, zinc, mercury, antimony, lead, bismuth, cadmium, chromium, thallium, or other various additives, such as disclosed in Japanese Patent No. JP 1257124 A and U.S. Pat. No. 5,011,602 to Totani, et al. In some embodiments, the activity of the additive can also be increased, such as described in U.S. Pat. No. 5,900,383 to Davis, et al.
Potential substrates or tools that consumers could use with the dispensing package include woven or nonwoven dish cloths, sponges, paper towel, hands, facial tissue, bathroom tissue, paper, napkins, woven and nonwoven substrates, towels, wipes, and cotton balls. The dispensing package could also be used with clothes for stain removal purposes. Suitable substrates can comprise personal, cosmetic or sanitary wipes, baby wipes, hand wipes, wipes used in car cleaning, household or institutional cleaning or maintenance, computer cleaning and maintenance and any other area in which a flexible substrate having a useful liquid treatment composition has application. These substrates (tissues or wipes) can be made from simple nonwovens, complex nonwovens or treated, high-strength durable materials. The substrate can be two-sided or have a barrier so that only one side is wet with the composition upon use. Such substrates are described in U.S. Pat. App. 2005/0079987 to Cartwright et al.
The composition can contain virtually any useful liquid compositions. Simple liquids such as water, alcohol, solvent, etc. can be useful in a variety of end uses, particularly cleaning and simple wiping applications. The liquid can be a simple cleaner, maintenance item or a personal care liquid suitable for dermatological contact with an adult, child or infant. Such compositions can be used in hospitals, schools, offices, kitchens, secretarial stations, etc. The compositions can also comprise more complex liquids in the forms of solutions, suspensions or emulsions of active materials in a liquid base. In this regard, such compositions can be active materials dissolved in an alcoholic base, aqueous solutions, water in oil emulsions, oil in water emulsions, etc. Such compositions can be cleaning materials, sanitizing materials, or personal care materials intended for contact with human skin, hair, nails, etc. Cleaning compositions used generally for routine cleaning operations not involving contact with human skin can often contain a variety of ingredients including, in aqueous or solvent base, a soil-removing surfactant, sequestrants, perfumes, etc. in relatively well- known formulations. Sanitizing compositions can contain aqueous or alcoholic solutions containing sanitizing materials such as triclosan, hexachlorophene, betadine, quaternary ammonium compounds, oxidizing agents, acidic agents, and other similar materials. Such compositions can be designed for treating or soothing human skin, including moisturizers, cleansing creams and lotions, cleansers for oily skin, deodorants, antiperspirants, baby-care products, sun block, sun screen, cosmetic-removing formula, insect repellent, etc. Moisturizer materials are preparations that reduce water loss or the appearance of water loss from skin. Cleansing creams or lotions can be developed that can permit the formulation to dissolve or lift away soil pigments, grime and dead skin cells. These creams or lotions can also be enhanced to improve removability of makeup and other skin soils. Cleaners for oily skin are often augmented with ethyl alcohol or isopropyl alcohol to increase the ability of the cleaner to remove excess oily residue. Deodorants and antiperspirants often contain, in an aqueous base, dispersions or emulsions comprising aluminum, zinc or zirconium compounds.
The composition may contain one or more additional surfactants selected from nonionic, anionic, cationic, ampholytic, amphoteric and zwitterionic surfactants and mixtures thereof. A typical listing of anionic, ampholytic, and zwitterionic classes, and species of these surfactants, is given in U.S. Pat. No. 3,929,678 to Laughlin and Heuring. A list of suitable cationic surfactants is given in U.S. Pat. No. 4,259,217 to Murphy. Where present, anionic, ampholytic, amphotenic and zwitteronic surfactants are generally used in combination with one or more nonionic surfactants. The surfactants may be present at a level of from about 0% to 90%, or from about 0.001% to 50%, or from about 0.01% to 25% by weight.
The compositions may contain suitable organic solvents including, but are not limited to, C1-6 alkanols, C1-6 diols, C110 alkyl ethers of alkylene glycols, C3-24 alkylene glycol ethers, polyalkylene glycols, short chain carboxylic acids, short chain esters, isoparafinic hydrocarbons, mineral spirits, alkylaromatics, terpenes, terpene derivatives, terpenoids, terpenoid derivatives, formaldehyde, and pyrrolidones. Alkanols include, but are not limited to, methanol, ethanol, n-propanol, isopropanol, butanol, pentanol, and hexanol, and isomers thereof. Diols include, but are not limited to, methylene, ethylene, propylene and butylene glycols. Alkylene glycol ethers include, but are not limited to, ethylene glycol monopropyl ether, ethylene glycol monobutyl ether, ethylene glycol monohexyl ether, diethylene glycol monopropyl ether, diethylene glycol monobutyl ether, diethylene glycol monohexyl ether, propylene glycol methyl ether, propylene glycol ethyl ether, propylene glycol n-propyl ether, propylene glycol monobutyl ether, propylene glycol t-butyl ether, di- or tri-polypropylene glycol methyl or ethyl or propyl or butyl ether, acetate and propionate esters of glycol ethers. Short chain carboxylic acids include, but are not limited to, acetic acid, glycolic acid, lactic acid and propionic acid. Short chain esters include, but are not limited to, glycol acetate, and cyclic or linear volatile methylsiloxanes. Water insoluble solvents such as isoparafinic hydrocarbons, mineral spirits, alkylaromatics, terpenoids, terpenoid derivatives, terpenes, and terpenes derivatives can be mixed with a water-soluble solvent when employed. The solvents can be present at a level of from 0.001% to 10%, or from 0.01% to 10%, or from 1% to 4% by weight.
The compositions optionally contain one or more of the following adjuncts: stain and soil repellants, lubricants, odor control agents, perfumes, fragrances and fragrance release agents, and bleaching agents. Other adjuncts include, but are not limited to, acids, electrolytes, dyes and/or colorants, solubilizing materials, stabilizers, thickeners, defoamers, hydrotropes, cloud point modifiers, preservatives, and other polymers. The solubilizing materials, when used, include, but are not limited to, hydrotropes (e.g. water soluble salts of low molecular weight organic acids such as the sodium and/or potassium salts of toluene, cumene, and xylene sulfonic acid). The acids, when used, include, but are not limited to, organic hydroxy acids, citric acids, keto acid, and the like. Suitable organic acid can be selected from the group consisting of citric acid, lactic acid, malic acid, salicylic acid, acetic acid, adipic acid, fumaric acid, hydroxyacetic acid, dehydroacetic acid, glutaric acid, tartaric acid, fumaric acid, succinic acid, propionic acid, aconitic acid, sorbic acid, benzoic acid, gluconic acid, ascorbic acid, alanine, lysine, and mixtures thereof. Electrolytes, when used, include, calcium, sodium and potassium chloride. Thickeners, when used, include, but are not limited to, polyacrylic acid, xanthan gum, calcium carbonate, aluminum oxide, alginates, guar gum, methyl, ethyl, clays, and/or propyl hydroxycelluloses. Defoamers, when used, include, but are not limited to, silicones, aminosilicones, silicone blends, and/or silicone/ hydrocarbon blends. Bleaching agents, when used, include, but are not limited to, peracids, hypohalite sources, hydrogen peroxide, and/or sources of hydrogen peroxide. When cleaning food contact surfaces, compositions for use herein may contain only materials that are food grade or GRAS, including, of course, direct food additives affirmed as GRAS, to protect against possible misuse by the consumer.
Preservatives, when used, include, but are not limited to, mildewstat or bacteriostat, methyl, ethyl and propyl parabens, short chain organic acids (e.g. acetic, lactic and/or glycolic acids), bisguanidine compounds (e.g. Dantagard� and/or Glydant�) and/or short chain alcohols (e.g. ethanol and/or IPA). The mildewstat or bacteriostat includes, but is not limited to, mildewstats (including non-isothiazolone compounds) include Kathon� GC, a 5-chloro-2-methyl-4-isothiazolin-3-one, Kathon� ICP, a 2-methyl-4-isothiazolin-3-one, and a blend thereof, and Kathon� 886, a 5-chloro-2-methyl-4-isothiazolin-3-one, all available from Rohm and Haas Company; BRONOPOL�, a 2-bromo-2-nitropropane1,3diol, from Boots Company Ltd., PROXEL� CRL, a propyl-p-hydroxybenzoate, from ICI PLC; NIPASOL� M, an o-phenyl-phenol, Na+ salt, from Nipa Laboratories Ltd., DOWICIDE� A, a 1,2-Benzoisothiazolin-3-one, from Dow Chemical Co., and IRGASAN� DP 200, a 2,4,4′-trichloro-2-hydroxydiphenylether, from Ciba-Geigy A.G.
The compositions can contain antimicrobial agents, including 2-hydroxycarboxylic acids and other ingredients, including quaternary ammonium compounds and phenolics. Non-limiting examples of these quaternary compounds include benzalkonium chlorides and/or substituted benzalkonium chlorides, di(C6-C14)alkyl di-short chain (C1-4 alkyl and/or hydroxyalkl) quaternaryammonium salts, N-(3-chloroallyl) hexaminium chlorides, benzethonium chloride, methylbenzethonium chloride, and cetylpyridinium chloride. Other quaternary compounds include the group consisting of dialkyldimethyl ammonium chlorides, alkyl dimethylbenzylammonium chlorides, dialkylmethyl-benzylammonium chlorides, and mixtures thereof. Biguanide antimicrobial actives including, but not limited to polyhexamethylene biguanide hydrochloride, p-chlorophenyl biguanide; 4-chlorobenzhydryl biguanide, halogenated hexidine such as, but not limited to, chlorhexidine (1,1′-hexamethylene-bis-5-(4-chlorophenyl biguanide) and its salts are also in this class. Another class of antibacterial agents, which are useful in the present invention, are the so-called "natural" antibacterial actives, referred to as natural essential oils. These actives derive their names from their natural occurrence in plants. Typical natural essential oil antibacterial actives include oils of anise, lemon, orange, rosemary, wintergreen, thyme, lavender, cloves, hops, tea tree, citronella, wheat, barley, lemongrass, cedar leaf, cedarwood, cinnamon, fleagrass, geranium, sandalwood, violet, cranberry, eucalyptus, vervain, peppermint, gum benzoin, basil, fennel, fir, balsam, menthol, ocmea origanum, Hydastis carradenisis, Berberidaceae daceae, Ratanhiae and Curcunta longa. Also included in this class of natural essential oils are the key chemical components of the plant oils which have been found to provide the antimicrobial benefit. These chemicals include, but are not limited to anethol, catechole, camphene, carvacol, eugenol, eucalyptol, ferulic acid, farnesol, hinokitiol, tropolone, limonene, menthol, methyl salicylate, thymol, terpineol, verbenone, berberine, ratanhiae extract, caryophellene oxide, citronellic acid, curcumin, nerolidol and geraniol. Other suitable antimicrobial actives include antibacterial metal salts. This class generally includes salts of metals in groups 3b-7b, 8 and 3a-5a. Specifically are the salts of aluminum, zirconium, zinc, silver, gold, copper, lanthanum, tin, mercury, bismuth, selenium, strontium, scandium, yttrium, cerium, praseodymiun, neodymium, promethum, samarium, europium, gadolinium, terbium, dysprosium, holmium, erbium, thulium, ytterbium, lutetium and mixtures thereof
When the composition is an aqueous composition, water can be, along with the solvent, a predominant ingredient. The water should be present at a level of less than 99.9%, more preferably less than about 99%, and most preferably, less than about 98%. Deionized water is preferred. Where the cleaning composition is concentrated, the water may be present in the composition at a concentration of less than about 85 wt. %.
The dispenser can be used to transfer a wide variety of compositions to a substrate. These compositions include hard surface cleaners and sanitizers, personal care cleaners and other products, hand sanitizers, dish soap, laundry pre-treater, food products such as marinades, car products such as cleaners or protectants, and baby care products such as baby lotion. Also, suitable are compositions, such as hypochlorite especially dilute (below 500 ppm) hypochlorite, that lack good stability on nonwoven substrates. Other examples of compositions that may lack stability are quaternary ammonium disinfectants or metal ions that can bind to nonwoven substrates.
In one embodiment, the substrate can undergo a color change or other physical property change during the process of application using the dispenser or during the cleaning process. These changes can include color change due to the addition of a colorless cleaner/disinfectant, color change due to the addition of a composition containing a dye, color change when dye is thermochromic, and changes over time as solvent evaporates to cool the wipe, a color change due to reaction of solvent with a pre-bound species (e.g. transition metals) on the wipe, texture changes in the non-woven, and the impact of the using a dyed or patterned non-woven. The composition or substrate can incorporate solvatochromic dyes to indicate the presence of bacteria as described in U.S. Pat. App. 2005/0130253. In one embodiment, the composition contains a dye that interacts with proteins or bacterial on surfaces to indicate whether the surface is substantially free of soil (protein) or bacteria. In one embodiment, the soil or bacteria is detected on the substrate. In one embodiment, the soil or bacteria is detected on the surface. Colorimetric assays utilizing sampling devices for the detection of protein in biological samples are commonly used across various industries (biotech, healthcare, food, etc). These sampling devices require minimal manipulation of the protein-containing samples and allow for rapid qualitative and quantitative results. Among the various available calorimetric protein assays is one disclosed in U.S. Pat. No. 4,839,295 to Smith, incorporated herein in its entirety, that utilizes a Bicinchonic Acid (BCA) protein assay. This assay is based on the initial complexation of Copper [II], hereinafter Cu++ or cupric ion, with protein peptides under alkaline conditions, with the reduction to Copper [I], hereinafter CuI or the cuprous ion, in a concentration-dependent manner. The ligand BCA is then added in excess, and a purple color develops (562 nm peak absorbance) upon binding of BCA with Cu+. Suitable detection devices are described in U.S. patent application Ser. No. 11/397,522 to Cumberland et al. filed Apr. 3, 2006 and U.S. patent application Ser. No. 11/427,469 to Cumberland et al. filed Jun. 29, 2006.
Methods of Use
Consumers enjoy the ease of use of the invention for reasons such as it utilizes cleaners differently, provides control such as no overspray, can be used one-handed, is compatible with wide variety of substrates, utilizes direct application so that no particles are aerosolized into the air, allows easy multi-tasking with other household activities, and is not limited by number of doses or wipes. Because of this flexibility, the consumer has more control to make the exact use conditions suitable to the task.
The dispensing package can be used as a one-handed method of cleaning a surface, where the consumer grabs a substrate in her hand, pushes the substrate down on the reciprocating actuator top of the dispensing package with her hand, allows the actuator top to move down and discharge a cleaning composition from the dispensing package to the substrate, and wipes the surface with the substrate. The substrate can be a paper towel, facial tissue, sheet of toilet tissue, a napkin, a sponge, a towel, the consumer's fingers or any other suitable woven or nonwoven substrate. Because the cleaning task takes only one hand, the other hand is free to perform another activity, such as holding a telephone, eating a snack and the task can be done quickly and easily without carrying the dispensing package to the area of the task.
Because the consumer is unfamiliar with the one-handed method of cleaning a surface, certain use indications on the dispensing package, any exterior packaging, or on advertising may be necessary to provide the consumer instant instruction on the use of the dispensing package. In one embodiment, a hand is depicted over the dispensing package. In another embodiment, a hand holding a substrate is depicted over the dispensing package.
This method of cleaning of the invention has several advantages. If the consumer is preparing dinner and using one hand to contact raw food such as chicken that may contain microorganisms, then the consumer can use the other hand to do one-handed cleaning and disinfection of the food preparation surface, such as a countertop. Using a traditional cleaning product, such as a spray bottle and paper towel, the consumer picks up the spray bottle with the hand that has been potentially contaminated with microorganisms and transfers those microorganisms to the spray bottle. If the spray bottle or other product dispenser is contaminated with microorganisms, then the consumer can pick up and transfer microorganisms from the product dispenser. In the case of the one-handed method of the invention, the consumer contacts the product dispenser only at the actuator component which dispenses the disinfecting composition. In this case, there is less likelihood of transmission of microorganisms from dispenser to hands or from hands to dispenser.
Another advantage of the method and package of the present invention is control during delivery of the composition. With traditional spray dispensers, the consumer must attempt to fit the spray pattern of the spray bottle dispenser to the area to be cleaned. Frequently, the cleaning surface contains additional items, such as food or decorative items, which the consumer may not wish to contact with the cleaning composition. With the method and dispensing package of the invention, the consumer can controllably apply the composition to the substrate and then controllably apply the substrate containing the composition to the cleaning surface. If the consumer were to try spraying the substrate with a traditional spray dispenser, then some of the composition would be aerosolized into the air and some of the composition would miss the substrate and contact other surfaces such as the hand or food items.
Another area of concern for consumers is microorganism contaminated surfaces within the bathroom, especially around the toilet area. Consumers have ready access to toilet tissue but no ready mechanism to use it for spot cleaning. The method of the invention allows the consumer to use toilet tissue, which has limited wet strength and scrubbing strength, to spot clean surfaces around the toilet and other bathroom surfaces without using two hands and without having to pick up the dispensing package. With a suitable composition within the dispensing package, the consumer may also use the dispensing package and method of the invention for personal hygiene use.
With traditional dispensers such as trigger sprayers, the consumer has limited ability to control the pattern of dispensing the composition onto a surface or a substrate. In one case, the substrate, such as sponges, may be rectangular and the dispensing package may deliver a circular application of product. To effectively apply product to a substrate, such as a sponge, it may be desirable to apply the composition in a rectangular or oval fashion, where the applied product is dispersed more in one dimension than in the other dimension. Additionally, with the hand or a paper towel in a hand or a toilet tissue in a hand, it may also be desirable to apply the composition to the substrate in a non-circular fashion or where one dimension is greater than another. The method of the invention has the advantage that with a properly designed actuator component and discharge orifices in the activator component, it may be possible to apply a non-circular pattern with one hand motion.
Some suitable substrates will not be stable long-term to all suitable compositions, for example toilet tissue or a sheet of facial tissue quickly loses its tensile strength when saturated with cleaning composition. Therefore, it is most suitable to wet the toilet tissue or facial tissue just before use. In some cases, the substrate loses at least 40%, or 50%, or 60%, or 70%, or 80%, or 90% peak dry tensile strength in machine or cross direction upon being loaded to full saturation with the composition. Peak dry tensile strength is the maximum load that a substrate can bear before breaking\rupturing under tension. With the method of the invention, these substrates may be useful for spot cleaning.
Other compositions are not stable on typical substrates, for example hypochlorite, especially dilute hypochlorite, is not storage stable on most nonwoven substrates as described in U.S. Pat. No. 7,008,600 to Katsigras et al. Additionally, compositions of very high or low pH are not generally storage stable on wipes or paper towels. Disinfectant compositions containing quaternary ammonium disinfectants or other cationic disinfectants bind to most nonwovens, especially cellulosic nonwovens, on storage so that they are not effectively released. The extent of binding can be measured by a quaternary recovery measurement on the wet substrate. The liquid squozate is acquired from the substrate by centrifugation after a seven day minimum requisite time of substrate-lotion equilibration. Substrates are put into a centrifuged tube for analysis, centrifuged at 3000 rpm for 15 min, and the liquid analyzed by HPLC. At equilibrium, the quaternary disinfectant show substantial binding to the substrate, for example, at least 10%, or 20%, or 30%, or 40%, or 50% by weight. However, the method of the invention, since it is quick and easy, lends itself to use of unstable substrates and unstable compositions, which may not be suitable under other methods of use.
The present invention relates to disinfecting compositions which can be used to disinfect various surfaces including inanimate surfaces such as hard surfaces like walls, tiles, floors, countertops, tables, glass, bathroom surfaces, and kitchen surfaces. The hard-surfaces to treat with the compositions herein are those typically found in houses like kitchens, bathrooms, e.g., tiles, walls, floors, chrome, glass, smooth vinyl, any plastic, plasticized wood, table top, sinks, cooker tops, dishes, sanitary fittings such as sinks, showers, shower curtains, wash basins, toilets and the like. Hard-surfaces also include household appliances including, but not limited to, refrigerators, freezers, washing machines, automatic dryers, ovens, microwave ovens, dishwashers and so on.
The dispensing package can be used around the house, for example, on kitchen or bathroom surfaces. The dispensing package can be used in public places, for example, in schools and school classrooms. For use around food, a food safe cleaner or disinfectant is suitable. The dispensing package allows the user to quickly apply a sanitizing or cleaning solution to everyday cleaning tools, such as sponges, paper towels, toilet paper, facial tissue, etc. When applied, the sanitizing or cleaning solution transforms the everyday cleaning tool into effective cleaning or sanitizing tools.
In one embodiment, the dispensing package is both a gel and mist cleaner. This dispenser is a dual dispensing cleaner that allows you to dispense one cleaner or two different cleaners in two different forms, a gel and a mist or spray. The package has a gel liquid transport assembly on top that works with a top actuator component as described previously and a liquid misting sprayer on the side. The unit contains one cleaning bottle and optionally a wall mounting base and attachments. To use this embodiment, press and pump your paper towel on the cleaning gel actuator component. To use the misting spray, squeeze the trigger on the side.
In one embodiment, the dispensing package is a discreet and mountable cleaner dispenser. This package is a mountable cleaning product package with a press and pump dispenser. The package is thin and discreet, about the size of a flattened tissue box. It can be mounted horizontally or vertically with adhesive to surface of your choice (e.g., under cabinets, side of counter, side of toilet tank, etc.). The unit contains one dispensing package with adhesive back. In another embodiment, the dispensing package is a hangable cleaner that can be hung anywhere (e.g., shower door/curtain rod, towel rack, kitchen cabinet, shower head, etc.) with the hook on top.
In one embodiment, the dispensing package is a mountable or counter standing dispenser that automatically dispenses the composition onto your paper towel, toilet paper, sponge, rag, etc. A sensor on the dispensing package works to activate the actuator component when you hold your paper towel, toilet paper, sponge, rag, etc. under or over the actuator component. The unit package can contain wall-mounting and counter-holding suction cups, dispensing machine, refillable cleaner cartridge and battery. In one embodiment, this dispensing package is plugged into an outlet to run the sensor and liquid transport assembly.
In one embodiment, the product or package contains directions to store the substrate on top of the package, for example a sponge on top of dispensing package actuator. In one embodiment, the product or package includes the dispensing package and substrates sold together, for example paper towels with the dispensing package. In one embodiment, several dispensing packages are bundled in multi-packs, for example a dispensing package containing dish soap and a dispensing package containing a kitchen cleaner. In one example, the dispensing package is sold with one or more refills.
While this detailed description includes specific examples according to the invention, those skilled in the art will appreciate that there are many variations of these examples that would nevertheless fall within the general scope of the invention and for which protection is sought in the appended claims.
|Cited Patent
|Filing date
|Publication date
|Jan 14, 1949
|Apr 22, 1952
|Frank M Darling
|Adjustable automatic fluid dispenser
|Sep 19, 1955
|Dec 18, 1956
|Benjamin D Menkin
|Fluid dispenser device
|Jan 12, 1972
|Jun 19, 1973
|K Gores
|Reservoir dispenser
|Nov 16, 1977
|Mar 27, 1979
|Mastman Gary J
|Hand-actuated liquid dispenser
|Nov 21, 1989
|Dec 18, 1990
|Nozzle for dispensing a product, in particular a foaming product
|May 16, 1989
|Jan 22, 1991
|The Pittway Corporation
|Atomizing pump
|May 31, 1991
|Jan 26, 1993
|Calmar Inc.
|Liquid pump dispenser having a stationary spout
|Jan 29, 1992
|Sep 7, 1993
|Calmar Inc.
|Miniature pump sprayer
|Feb 17, 1994
|Nov 1, 1994
|Calmar Inc.
|Non-removable container closure
|May 2, 1994
|Aug 29, 1995
|Calmar Inc.
|Tamper evident lock for liquid pump dispenser
|Jan 5, 1995
|Aug 13, 1996
|Calmar Inc.
|Bellows pump dispenser
|Aug 3, 1994
|Aug 27, 1996
|Toyo Seikan Kaisha, Ltd.
|Pump with back suction phase
|Feb 7, 1995
|Jan 14, 1997
|Calmar Inc.
|Pump sprayer having variable discharge
|May 15, 1995
|Sep 9, 1997
|The Procter & Gamble Company
|Pump device with collapsible pump chamber having supply container venting system and integral shipping seal
|Mar 11, 1996
|Feb 24, 1998
|Calmar Inc.
|Pre-compression pump sprayer having improved inlet and discharge valving and an improved pump priming feature
|Mar 4, 1996
|Mar 31, 1998
|Park Towers International B.V.
|Spray head intended for a spray can, and spray can provided with such a spray head
|Apr 7, 1997
|Apr 14, 1998
|Calmar Inc.
|Liquid dispensing pump having water seal
|Apr 10, 1996
|Jul 28, 1998
|Calmar Inc.
|Precompression pump sprayer having suck-back feature
|Mar 17, 1999
|Apr 4, 2000
|Calmar-Monturas, S.A.
|Fluid pump dispenser
|Aug 17, 1999
|Dec 12, 2000
|Calmar Inc.
|Anti-clog pump sprayer
|Apr 28, 1999
|Dec 12, 2000
|Humphreys; Ronald O.
|Liquid dispenser with multiple nozzles
|Aug 9, 1999
|Jan 16, 2001
|Owens-Illinois Closure Inc.
|Pump dispenser having a plunger seal
|Mar 8, 2000
|Jan 16, 2001
|Calmar Inc.
|Nasal sprayer with folding actuator
|Aug 28, 2000
|May 1, 2001
|Calmar Inc.
|Anti-clog pump sprayer
|Jun 1, 2000
|Jul 10, 2001
|Saint-Gobain Calmar Inc.
|Anti-clog pump sprayer
|Aug 17, 2000
|Aug 7, 2001
|Saint-Gobain Calmar Inc.
|Vial access spike adapter for pump sprayer
|Oct 11, 2000
|Jan 15, 2002
|Saint-Gobain Calmar Inc.
|Actuation device for manually operated pump sprayer
|Jan 24, 2002
|Nov 5, 2002
|Saint-Gobain Calmar Inc.
|Unit dose tube and cap assembly
|Apr 12, 2002
|Apr 8, 2003
|Saint-Gobain Calmar Inc.
|Child-resistant liquid dispenser
|Feb 12, 2002
|Feb 24, 2004
|Seaquistperfect Dispensing Foreign, Inc.
|Pump dispenser
|Feb 26, 2003
|Mar 9, 2004
|Saint-Gobain Calmar Inc.
|Self-aligning pump assembly
|Sep 27, 2000
|Apr 6, 2004
|The Procter & Gamble Company
|Hard surface cleaning compositions, premoistened wipes, methods of use, and articles comprising said compositions or wipes and instructions for use resulting in easier cleaning and maintenance, improved surface appearance and/or hygiene under stress conditions such as no-rinse
|May 27, 2003
|May 4, 2004
|Saint-Gobain Calmar, Inc.
|Twirling dip tube
|Dec 20, 2002
|Aug 24, 2004
|Saint-Gobain Calmar Inc.
|Weighted dip tube for a manual dispenser
|Nov 12, 2003
|Oct 11, 2005
|Saint-Gobain Calmar Inc.
|Liquid dispenser and cleaner
|Mar 17, 2000
|Oct 4, 2001
|Willi Lorscheidt
|Dispensing pump, dispenser and dispenser unit-assembly
|Apr 10, 2002
|Oct 16, 2003
|Saint-Gobain Calmar Inc.
|Swivel pump dispenser for dispensing liquid from a selected one of plurality of liquid compartments
|Nov 12, 2003
|May 12, 2005
|Saint-Gobain Calmar Inc.
|Liquid dispenser and cleaner
|Apr 6, 2004
|Oct 13, 2005
|Mon Thomas K
|Pump dispenser and cartridge
|Dec 12, 2006
|Jun 12, 2008
|Timothy James Kennedy
|Fluid Dispensing Systems for Pump Dispenser
|Dec 12, 2006
|Jun 12, 2008
|O'connell Tami
|Fluid Dispensing Systems For Pump Dispenser for Use With Substrates
|Dec 12, 2006
|Jun 12, 2008
|Timothy James Kennedy
|Pump Systems for Pump Dispensers
|Jan 9, 2007
|Jul 10, 2008
|Timothy James Kennedy
|Fluid Dispensing System with Separate Pump Actuator and Dispensing Pad
|Jun 25, 2007
|Dec 25, 2008
|Timothy Kennedy
|Gravity-Flow Liquid Drain-Back System for a Dispensing Package
|Jan 18, 1991
|Jul 25, 1991
|Dunne Miller Weston Limited
|Atomising valve assemblies
|http://www.saint-gobain-calmar.com/products.aspx?c=prod&sc=2&pid=20 (Calmar MD3200)-Oct. 19, 2006.
|http://www.saint-gobain-calmar.com/products.aspx?c=prod&sc=2&pid=20 (Calmar MD3200)—Oct. 19, 2006.
|Citing Patent
|Filing date
|Publication date
|Dec 8, 2008
|Feb 14, 2012
|Kimberly-Clark Worldwide, Inc.
|Anti drip fluid dispenser
|Dec 8, 2008
|Jun 10, 2010
|Richard Paul Lewis
|Anti drip fluid dispenser
|Mar 14, 2014
|Nov 18, 2014
|The Clorox Company
|Fluid dispenser
|Jun 16, 2015
|Dec 23, 2015
|The Procter & Gamble Company
|Wet/dry sheet dispenser with dispensing cup
|U.S. Classification
|222/108, 222/321.3, 222/205, 222/321.6
|International Classification
|Cooperative Classification
|European Classification
|Jun 27, 2007
Owner name: THE CLOROX COMPANY, CALIFORNIA
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:KENNEDY, TIMOTHY;O CONNELL, TAMI;REEL/FRAME:019490/0234
Effective date: 20070626
Owner name: THE CLOROX COMPANY,CALIFORNIA
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:KENNEDY, TIMOTHY;O CONNELL, TAMI;REEL/FRAME:019490/0234
Effective date: 20070626
|Dec 2, 2013
|Fee payment
Year of fee payment: 4


text:
Frequently Asked Questions
Where are the branch and affiliate libraries?
The NCSU Libraries is made up of the two main libraries: the D. H. Hill Library on Central Campus and the James B. Hunt Jr. Library on Centennial Campus; and three branch libraries: Design, Natural Resources, and Veterinary Medicine. These branches are located with the colleges that they serve. The affiliated libraries/reading rooms are the African American Cultural Center Reading Room and the Media and Educational Technology Resource Center (METRC).
Branch Libraries:
Design Library
Natural Resources Library
Veterinary Medicine Library
Affiliated Libraries and Reading Rooms:
African American Cultural Center Reading Room
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text:
Look out for horses in flooded fields says WSPCA
PEOPLE have been asked to be alert to the danger of horses being trapped in flooded fields over Christmas.
With more heavy rain and storms forecast, the WPSCA said it feared that horses left out to graze could become isolated and left starving.
'We were called out to Duncormick a few days ago where two horses were trapped, however there was a strip of ground where they were standing and we managed to trace the owner, who said he would deal with the problem,' said a WSPCA member, who looks after horses.
'We get a lot of calls from people who see horses trapped in flooded fields. If anyone spots a real emergency they should call on 087 9884272,' she said, adding that for the first time in several years there had so far been no reports of horses trapped on what is known locally as the Island, in Enniscorthy.
Meanwhile, the WSPCA is looking for good homes for six horses and cobs. Call 053 9143919.
Wexford People


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Posts Tagged 'ecosia'
Aiming a different prosperity: Ecosia
January 30, 2011 1 comment
I came across this amazing corporation where ecological and social goal is written in their constitution. Unlike some other corporations, their goal is not about relentless and mindless pursuit of profit growth: Ecosia internet search engine donates %80 of his income to support WWF's work in the Amazon to save the rainforest.
Please check it out www.ecosia.com


text:
Free forum : Gold prospecting amateurs and professionals alike-West Australian. APLA. Members of the Outback club.
gold, forum, prospecting, detecting, west, western, detector, minelab, gpz7000, alluvial, eluvial, #mining, detectors, prospectors, nuggets, vehicles, fishing
Gold prospecting and mining talk, information and tips on how to find gold, locations to look, techniques to employ and fun stories and trip reports to learn from.
goldadventures, gold, prospecting, #mining, talk, tips, locations, techniques, employ, stories, trip, reports, learn
Live Runescape Classic server. free to play
classickbd, runescape, classic, rsclassic, rsckbd, rune, scape, quest, guide, skill, #mining, smithing, runecrafting, attack, defense, strength, hits, ranged, magic, prayer, cooking, woodcut


text:
Thursday, November 24, 2016
Happy Thanksgiving!
6 comments:
Happy Thanksgiving, LeAnne to you and your family. Love your decorations, especially your turkeys. That's quite a collection.ReplyDelete
Love all your Thanksgiving decorations, LeAnne! Wishing you & your family a happy & blessed Thanksgiving today! We all have alot to be thankful for! <3ReplyDelete
Thank you, LeAnne, and right back to you ... I'm stuffed like a turkey, have donned my Thanksgiving pants, and we're off to the movie theater! LOve all of your fabulous decorations BUT I must tell you: my MOm had those exact little candles - OH you are the lucky one to have them!!! xxReplyDelete
What fun decorations! Happy thanksgiving!ReplyDelete
Love your collection of turkeys!! Thank you for sharing!ReplyDelete
Love your turkeys and Thanksgiving decorations. I have a pilgrim couple in candlesticks, different than yours but special all the same. :) Thanksgiving is my favorite holiday and my anniversary falls on that weekend, too. :) blessings to your family!ReplyDelete
Thanks so much for your comments! I love hearing from you! If you have a question, please be sure to include an email address so I can respond to you quickly!


text:
For any questions please call toll free 800-399-0602
A combination of wood, ceramic and glass gives this vanity a modern designer look. A drawer bridge cabinet provide storage space. The front panel is accented by a frosted glass insert. A ceramic sink with space for toiletries adds function and convenience. A maching mirror.
Set includes:


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Dec 03, 2013 Sarah Hall Uncategorized
Ethan Bramoff went into the Target in Cicero the morning of Sunday, Dec. 1, with a $100 gift card, a list and a mission: to purchase Christmas gifts for everyone in his family.
"Usually I go with my mom and dad," said Ethan, 6, a first-grader in Mrs. McAvoy's class at Cicero Elementary, "and I get everything with them."
But this year, Ethan had a different shopping buddy: Cicero Police Officer John Fortino.
Ethan was one of several Cicero youth selected to take part in the Cicero Police Department's Shop with a Cop program. Children between the ages of 6 and 11 years old are asked to write an essay explaining why they'd like to shop with a member of the police department and describing what the holiday season means to them. Children must be residents of the town of Cicero. Winning essays are selected by members of the Cicero Police Benevolent Association.
Each child is given a $100 Target gift card, provided by a $1,000 grant Target supplies to the Cicero PBA each year.
The program began in 2009.
As for Ethan, in addition to getting to buy his own gifts this year, the main reason he wanted to participate in the program was simple.
"Cops are awesome," he said.
Sarah Hall is the editor of the Eagle Star-Review and the Baldwinsville Messenger. The 2012 winner of the Syracuse Press Club's Selwyn Kershaw Professional Standards Award, she has been with Eagle Newspapers since 2006. She is a Liverpool native.
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Car Exhaust Systems Explained
Without the internal combustion engine, our cars would not operate the way we are used to. And without our cars exhaust system, the combustion engine would not operate properly at all. Once the combustion stroke is complete, the gases that are created must have an escape route or they will become trapped inside the engine and cut off the oxygen supply. It is the responsibility of the exhaust system to take away these emissions from the engine and do so in a quiet and efficient manner. Following is how a cars exhaust system works.
The quiet aspect of an exhaust system is handled by one or more mufflers. A small explosion results from the compression of fuel and air in an internal combustion engine, and though not very large, it still creates a racket. We usually do not comprehend just how loud this fire is until we are next to a car that has a hole in its muffler. It is enough to drown out the very thoughts in our own heads, much less render the radio useless. The muffler cancels this noise out either by way of a restrictive tube passing through insulation materials, or by using noise cancellation technology. Whatever sound frequencies are left over are whisked out of the tail pipe at the rear of the car and as far away from the driving compartment as possible.


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InCube success key to S.A.'s biomed future
BioMed SA Chairman Henry Cisneros is optimistic that San Antonio made the right decision to invest in a new InCube Labs biosciences company that will be headed by California entrepreneur Mir Imran.
But he also says if that venture is unsuccessful, it could cost the Alamo City confidence and opportunities.
"I think we've got to move heaven and earth to make this work," Cisneros says.
Local leaders in the public- and private-sector have extended a multimillion-dollar investment deal to Imran to entice him to set up the InCube incubator in the Alamo City. The deal, if it goes well, those leaders argue, could prove to be a major shot in the arm for the city's biosciences industry.
However, Imran's plan to set up an InCube Labs biosciences incubator facility in the Alamo City capable of launching multiple companies comes with a steep price, in terms of dollars and risk.
The City of San Antonio is investing $6 million in public funds to help cover the costs associated with developing and launching the Northwest Side lab facility and Bexar County is investing $2 million. The Texas Research & Technology Foundation is investing $1 million, while the University of Texas at San Antonio and the University of Texas Health Science Center at San Antonio are each investing $500,000 in the InCube project.
San Antonio City Manager Sheryl Sculley says Imran plans to invest as much as $15 million in the San Antonio lab.
Ed Davis, assistant director of the City of San Antonio's Economic Development Department, says the public investors will collectively hold a 5 percent stake, in the form of founders common stock, in each of the companies launched by the Alamo City InCube lab.
Davis says, based on conservative estimates, the City of San Antonio could recoup about 90 percent of its investment within the first seven to 10 years. But that assumes some of the companies launched out of the incubator prove to be successful in the commercial market.
Sustain confidence
Cisneros, who helped create BioMed SA, a nonprofit organization that promotes the city's health care and biosciences assets, says if the InCube deal pans out, it could "build a reputation for San Antonio" that opens new doors.
"We missed out on the manufacturing wave," says Cisneros, a former mayor of San Antonio and past Secretary of Housing and Urban Development. "We missed out on the technology wave. When you look at the opportunities ahead for San Antonio, the greatest potential is in the biosciences. Therefore (the InCube deal) is worth some higher level of investment and, yes, even risk."
But the former mayor acknowledges that, while San Antonio has everything to gain from this relationship with Imran, it also has plenty to lose.
"Frankly, if we were to fail, I think it would dampen confidence for this kind of investment," he says. "We're not so large (a city) that we could just rebound from this and move on to the next deal.
"In order to sustain confidence all around the table — with the investors, the public sector, the research institutions, the medical groups — we need to make this work," he adds. "We want to be able to move on to the second and the third and the fourth deals. But it will be much harder to do that if people have been disappointed by the first."
Says Bexar County Judge Nelson Wolff about the InCube deal: "I do think it is important that we all understand that there is risk involved in this. But for the long-term benefit of the community in an effort to jump-start our biosciences industry, this is a risk work taking."
The city's health care and biosciences industries combined produced a $16.3 billion economic impact for the city in 2007 (the most recent data available), according to a report by the Greater San Antonio Chamber of Commerce. However, by far, the bulk of that economic impact is derived from the city's health care sector, which includes multiple civilian and military hospital systems. According to the Greater Chamber report, nearly $10 billion of that $16.3 billion impact was generated from health care-related services.
Good progress
Imran says it's crucial that he secure private-sector funding, too. He says the kinds of companies he hopes to launch in San Antonio will have "an insatiable appetite for money."
Imran hopes to secure $100 million for a separate InCube Ventures II venture capital fund that would help support companies launched from the San Antonio incubator.
USAA is among the San Antonio companies that has pledged to invest about $10 million in that fund, according to sources close to the deal.
"It's a very long-term investment," says Chris Claus, president of USAA's Financial Advice and Solutions Group. "It's probably a minimum of 10 years before you start to see some form of payback, so you have to be extremely patient. We did a lot of due diligence and found that this was an investment that made sense for us."
"We have made good progress with our fund raising efforts," says InCube's Stephanie McGrory. "We have received tremendous support from our San Antonio investors."
York Duncan, president of the Texas Research & Technology Foundation, an innovation-based economic development organization, says his group has leased a 20,770-square-foot building at 12500 Network Boulevard where the InCube lab will be located. It is sub-leasing 16,500 square feet of space in that facility to Imran's company. Duncan says it was a way to ensure that the space would remain in the hands of local interests should the InCube venture not work out as planned.
Duncan says the public investor money is being used to modify the building, which will house a substantial amount of equipment necessary to accommodate a research and development lab, a wet lab and engineering space.
"There is a lot of risk involved in this (InCube investment). People need to understand that," Duncan explains. "But there is also an opportunity for a high reward."
Imra plans to launch five life science companies from his San Antonio InCube Labs venture over the next five years. City leaders are also hopeful that Imran will move as many as three existing companies to the Alamo City.
Cisneros says San Antonio has made the commitments necessary to support Imran's vision.
"We have brought together all of the elements of the biosciences community here in a supportive role," he says. "We've also put ourselves in a position to help him commercialize and promote. So I think San Antonio has offered the full range (of support) available.
"Now together we will have to execute," Cisneros adds. "Imran will have to come up with the ideas. Funds will have to be allocated. The right team will have to be attracted (to San Antonio)."
Imran is the central figure in all of this. His ability to lead the InCube venture in San Antonio long-term is essential, local leaders explain.
"He is key to a lot of this," Davis says.
"The crucial element that we hope we have invested in, is Mir Imran's continued innovation and imagination," Cisneros explains. "The critical ingredient is the continual stream of ideas that come from the very fertile brain of Mir Imran.
"He's been very successful spawning 25 medically related ideas that were strong enough to actually become companies," Cisneros adds. "That is quite a record. Mir Imran's success is our success."


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Honeywell International Inc. (NYSE:HON) has been downgraded to Buy in a statement by Goldman Sachs Group Inc. earlier today.
- Updated: October 10, 2016
Only yesterday Honeywell International Inc. (NYSE:HON) traded -7.50% lower at $106.94. The company's 50-day moving average is $115.34 and its 200-day moving average is $115.12. The last closing price is down -7.10% from the 200-day moving average, compared with the S&P 500 Index which has decreased -0.01% over the date range. Trade Volume was up over the average, with 20,446,322 shares of HON changing hands over the typical 2,948,420
Goldman Sachs Group Inc. has downgraded Honeywell International Inc. (NYSE:HON) to Buy in a report released on Monday October 10, 2016.
On Thursday October 06, 2016, Robert W. Baird released a statement on Honeywell International Inc. (NYSE:HON) increased the target price from $0.00 to $135.00 that indicated a possible upside of 0.17%.
See Chart Below
Honeywell International Inc. has P/E ratio of 16.92 with a 52 week low of $93.71 and a 52 week high of $120.02 and has a market capitalization of $0.
A total of 19 brokerages have issued a ratings update on the company. 7 brokers rating the stock a strong buy, ten equity analysts rating the company a buy, 4 firms rating the stock a hold, zero analysts rating the stock a underperform, and finally 0 brokerages rating the stock a sell with a average stock price target of $125.63.
About Honeywell International Inc. (NYSE:HON)
Honeywell International Inc. (Honeywell) is a technology and manufacturing company. The Company operates in three segments: Aerospace, Automation and Control Solutions (ACS), and Performance Materials and Technologies (PMT). Its Aerospace segment supplies aircraft engines, integrated avionics, systems and service solutions, and related products and services for aircraft manufacturers, airlines, aircraft operators, military services, and defense and space contractors. The ACS segment provides environmental and energy solutions; sensors, switches and controls for sensing and productivity solutions; security and fire safety products; industrial safety products, and building solutions and services for homes, commercial buildings and industrial facilities. The PMT segment develops and manufactures materials, process technologies and automation solutions. Its PMT segment includes UOP Russell LLC (UOP), Process Solutions and Advanced Materials businesses.
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