text:
... from desktop to tablets and smartphones. The dating script supports multiple languages, including RTL languages, and the design themes match this layout automatically. Dating Pro lets you run a free trial: www.datingpro.com . Start a profitable online dating community with the PG Dating Pro software. Build a uniquely different platform .... Free download of Dating Pro Template 2017.7
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The nutritional information on the back of a box will tell you what the brand recommends as a serving size -- often an underestimate to make the product appear healthier. Bryan Ku's pasta packaging approaches appropriate portions in a more practical way and actually aids the cook in food preparation with measuring cups worked into each canister.
Each receptacle takes a cylindrical form but the penne and farfalle cartons have caps that double as gauges. From the principle container, you pour the sculpted noodles into the lid until they meet the top. Each capful is one serving. Spaghetti, however, is a little trickier to dispense in this way. In this case, Bryan Ku's pasta packaging incorporates a turning top to release a limited bunch of sticks from a small opening.
Unpublished - Duplicate
Set-Serving Spaghetti Branding
More Stats +/-
Nostalgic Lunch Bag Branding
Cutout Character Branding
Veggie-Branded Edibles
Flexible Fruit Branding
Lumber Hive Branding
Bryan Ku's Pasta Packaging Serves Up Proper Portions
- By: Amelia RoblinJul 10, 2012
References: bryanku & lovelypackage
References: bryanku & lovelypackage

subset: commoncrawl


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Norm's Car Care
Review for Norm's Car Care
barb t. on 06/23/2015
"Wheels making weird noise."
Dan drove my Nissan around the block and figured out the noise was from a bent piece, most likely from hitting a pot hole. He fixed it right then and there!!!!!
Service Date: 06/23/2015
Review Created: 06/23/2015 05:42 PM


text:
Main Barriers to Education
- Conflict & security
- Lack of trained teachers
- Gender discrimination
Interventions to Barriers
- Data maintenance & analysis
- School management & teacher training
- Psychosocial support & alternative curriculum
In a region that has known all too brief episodes of peace and stability since the onset of the MDGs in 2000, some countries have made veritable strides towards universal primary education and the MDGs. Iraq has been unable to outpace its circumstances in this regard. Though the government is committed to providing free quality education (from primary through higher education), strengthening its national education system and building capacity, the challenges afflicting Iraq's education sector are prevalent. To date – according to UNESCO there are approximately 227,000 Syrian refugee children in the country as a result of the conflict.
In recognition of its challenges, the government has identified pre-service and in-service teacher training, OOSC enrolment, particularly for girls, and developing curriculum specifically for children in crisis-affected areas as priorities.
In an attempt to support Syrian refugee children within Iraq's borders, EAC has partnered with the U.S. Fund for UNICEF. The project specifically seeks to increase access to safe-learning spaces, expand remedial education, and strengthen alternative education programmes for OOSC, as well as construct and rehabilitate learning spaces and support teacher-training initiatives.
Geographic Location: Middle East
Languages: Arabic (official), Kurdish (official), Turkmen, Assyrian and Armenian


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Buffyversed is a week by week, episode by episode, re-exploration of Buffy the Vampire Slayer. Look for it every Friday on Goomba Stomp. For previous episodes click here.
Last week we may have talked about "The Harvest" but this week it's here!
Now, what exactly is The Harvest, you might be wondering. Well, allow me to explain: The Master transfers some of his blood into a surrogate, who will then feed on blood until The Master has enough power to break the magical hoodoo seal which is still holding him underground.
But maybe we're getting a bit ahead of ourselves. As you might recall, last week's episode, "Welcome to the Hellmouth", ended with that old television adage: To Be Continued. The cliffhanger in question centered around Willow, Xander and Jesse being surrounded by vampires in the graveyard, while Buffy was about to be feasted upon by The Master's second in command, Luke.
Well, as to the latter, careful watchers (like Giles) will remember that Angel gifted Buffy with a cross in the premiere… a cross she just so happens to be wearing! It gives her just the edge she needs to take back the advantage in the fight, and as Luke somehow disappears, Buffy rushes out to save her new friends. Unfortunately, she's too late as far as Jesse is concerned, but let's just remember for posterity that Jesse is kind of a douchebag anyway (see actor Eric Balfour, above, for reference).
In spite of his douchebaggery, Buffy and Xander head off to rescue him anyway, only to find that "too late" is something of an understatement here. Jesse has joined the kingdom of the undead, making him not just a lifelong douchebag, but an immortal one (more on that later).
Meanwhile, classic high school stuff plays out in the interim, as nerds are bullied by the popular folk, and then use their brains for vengeance. Demonstrably, Willow telling Cordelia to use the "deliver key" to save her work is pretty great (hint: that's not what DEL does). Unfortunately, nerds seeking vengeance will one day become the motif of one of the series' darkest moments…but let's not think about that now, okay?
Ye olde comic relief Xander comes to the conclusion that if there's to be a Harvest, it will almost certainly be at the regular series social device: The Bronze. Snark aside, The Bronze has to be the most convincing teenage club ever seen in a television drama, or certainly at least up until the time when Buffy the Vampire Slayer premiered.
So, to The Bronze we go! The vampires arrive first in a surprisingly cinematic slow-motion approach set to angsty alternative rock. Give our director, John T. Kretchmer, some credit for that one. Next, Buffy infiltrates the joint and finds herself toe-to-toe with Luke, but not before some notable Spiderman-esque banter with the villain. As any fan will know, this is far from the last time that this will occur.
Points must be given for the sunlight fake-out Buffy uses to distract Luke, as well as the hilarious way that Brian Thompson, who plays Luke, reels with roaring dismay before realizing he's been had. And had he has been, as the Scoobies usher the other waiting victims out of The Bronze while Buffy scares off the remaining vampires with nothing more than a badass stare down after staking Luke.
In other news, Xander is accidentally relieved of the burden of deciding whether to kill Jesse or not when a frantic passerby simply bumps him into Xander's waiting wooden stake. Classic!
So, the plan is averted, and the high schoolers who witnessed the attempted Harvest "rationalize what they can understand, and forget what they can't." Things are more or less back to the status quo, but unfortunately the status quo is still on the Hellmouth, so look forward to many more supernatural hijinks to come.
Next week will be the first of many switch-ups on the formula, as vampires are moved to the back burner to focus on a more magical threat. See ya in seven!
Now allow me to introduce the two post categories that will follow every episode. The first, "Cristina Says," will be based on observations my fiance makes. This is my 4th time through the series, but she's a first-time watcher with 2017 TV sensibilities, so I thought it would be interesting to note what a first-timer would observe.
The second category is something I'm calling "Notable Whedonisms." Whedonisms are a sort of term for Whedon's style of dialogue, and something I'll be using as a catch-all for particularly fun or witty lines.
And awaaaaaaaaaaayyyyy we go!
Cristina Says:
"I don't remember her wearing that huge cross in the first episode." (To her credit, she's technically right about Buffy not wearing it. It's sort of like a bullet proof vest fake out in an action movie. Luckily, in this case, Chekhov's Cross was at least introduced last week.)
"When was this made again?" (Regarding Willow's usage of the internet to pull up city schematics for the sewer system. To be fair, the internet absolutely existed in 1997, but this is some standard '90s hacker trope silliness)
"Good wedding vows!" (After The Master delivers the line: "My blood is your blood, my soul is your soul!" And Luke responds: "My body is your instrument." She's certainly my fiance!)
Notable Whedonisms:
"If you're gonna be popping up with this cryptic wise man act, then you can at least tell me your name." (Buffy to Angel, after he pops up with his cryptic wise man act.)
"We need to get out of here!" "There is no out of here!" (Buffy and Xander, when they're trapped in the sewers with vampires.)
"He came for the town's mystical whoozit!" (Buffy answers Giles' question as to why The Master chose Sunnydale.)
"Don't go Wild Bunch on me." (Buffy instructs the Scoobies to just get the innocent bystanders out, rather than opting for anything too crazy.)
Thanks for reading fellow Scoobies! We'll be back for more with "Witch" in a solid seven!


text:
Certain jeopardy / Alton Gansky.
Electronic resources
Record details
- ISBN: 9780805464535 (electronic bk)
- Physical Description: 1 online resource
- Publisher: Nashville : B&H Books, 2011.
Content descriptions
|General Note:
| Title from eBook information screen..
|Summary, etc.:
| U.S. Special Ops approach an Al Qaeda base in Venezuela and discover its plans to transport a nuclear weapons expert to Iran. The debut novel from U.S. Army Ranger & Chaplain Jeff Struecker.
|System Details Note:
| Requires OverDrive Read (file size: N/A KB) or Adobe Digital Editions (file size: 547 KB) or Amazon Kindle (file size: N/A KB).
Search for related items by subject
Christian Fiction.
|Electronic books.


text:
By Timothy Bella
DENVER, Colo. (CBS Denver) — Tim Tebow could be a deciding factor come January — not just for a possible playoff game involving the Denver Broncos — but for which Republican wins the Iowa caucus.
A recent poll out of Iowa indicates that Tebow's Christianity and pro-life support corresponds to the current Iowa electorate, the first major test in deciding a Republican nominee. Iowa residents who view Tebow favorably have former House Speaker Newt Gingrich as their first choice for the Republican nomination at 29 percent, according to a recent Public Policy Polling poll. Gingrich, whose recent surge in the polls has him as the Republican front-runner, won the Tea Party Straw Poll conducted by the Tea Party Patriots on Sunday, taking home 31 percent of the vote among the 23,000-plus supporters of the cause who took part in the poll.
On the flip side, the PPP poll found that those Iowa residents who looked at Tebow unfavorably have Texas Rep. Ron Paul as their first choice with 38 percent. Paul garnered just 3 percent of the vote in the Tea Party straw poll.
Whether a sect of Tebow fans should be directly linked to Tea Party loyalists cannot be quantified, but the connection to Gingrich in the PPP poll and a stamp of approval from fellow evangelical Sarah Palin during the weekend makes it clear that some of the Tea Party's most notable and supportable figures are all about Tebowmania.
"I am so pro-Tebow, you know he is so unashamed of his savior, Jesus of Nazareth," Palin told Fox News on Sunday. "He knows Jesus is going to rock your world when you give it over to him, and he's bold about it, and he knows that the son of God should be honored and praised. Tebow does that and I respect it."
Maybe it comes as no surprise that one of the more religiously-fueled politicians of the past decade has supported one of the more religiously-fueled athletes of the same time period. Steven F. Hayward, a resident scholar at the American Enterprise Institute in Washington D.C., told CBS Denver that the religious right layer of the Tea Party is the one most making its voice heard in regard to someone like Tebow, whose act of kneeling and praying before the game, or "Tebowing," has become a nationwide phenomena.
"Among religious-minded people, there's lot of affection for figures like Sarah Palin or athletes like Tim Tebow as people who make public expressions of faith," Hayward said. "People rally to that person."
And other Republican politicians and pundits are getting in on the Tebow craze. Just last week, Texas Gov. Rick Perry, once a favorite of Tea Partiers who has since seen his support from the group become nonexistent, identified who he wanted to be heading into January's Iowa caucuses.
"I hope I am the Tim Tebow of the Iowa caucuses," Perry said last week. "There are a lot of folks that said Tim Tebow wasn't going to be a very good NFL quarterback. And, you know, he won two national championships. And that looked pretty good."
In Iowa, radio host Chuck Laudner likened Rick Santorum to the Broncos quarterback last week, touting the candidate as something of an underestimated dark horse in Iowa.
"They're watching the Tim Tebow of the Republican process out there, working all the way through the fourth quarter," Laudner said.
But with Tebow's rise come his critics. Tebow and the Broncos haven't been free from viral campaigns aimed to address social issues. Recently, the Denver Broncos declined a request to join up with the "It Gets Better" campaign, which attempts to curb suicides among lesbian, bisexual, gay and transgender teens who have been bullied. "It's the good Christian thing to do," petition organizer Andy Szekers, a Denver Broncos fan, said in the petition. Earlier this year, Tebow's publicist prevented the quarterback from answering a question about same-sex marriage in an interview with the Washington Post.
Last week, a pro-choice blogger started a campaign for people to donate $10 for every touchdown Tebow scored on Sunday. In 2010, Tebow participated in an ad for Focus on the Family that ran during the Super Bowl, which talked about the importance of being pro-life. The blog post would go viral on Twitter, starting a discussion on a social issue in a political context involving an athlete.
"My issue with Tebow is neither his religion nor his anti-choice beliefs, rather, his advocacy for the anti-choice cause," Sophia Brugato, the blogger of the post, told CBS Denver late last week. "He's put himself, purposely, in front of the anti-choice movement with the message that 'if I was aborted, I wouldn't be here as the most amazing quarterback on the planet.'"
With the PPP poll drawing an indirect link between Tebow and Tea Party politics, there could be a question one day of whether Tebow would get into politics and if he would associate himself with the Tea Party. In 2009, then-Fla. Gov. Charlie Crist said that he had spoken to Tebow about a future in politics. "We've talked about it a little bit," Crist said. "I'd be more than honored to try to help him in some small way. Our state and our nation needs great leaders like him."
Although there could be juice behind Tebow shifting to politics when his playing days are over, Hayward said that the odds of the Tea Party uniting around a figure such as Tebow, wouldn't be that strong.
"The Tea Party is impossible to unite around one person," Hayward said, adding that Palin was the closest to being that person. A New York Times/CBS News poll last year found that despite two-thirds of Tea Partiers having a favorable opinion of Palin, 47 percent said she lacks the ability to be an effective president. "If the Tea Party tried to become an actual party like Ross Perot's Reform Party, that's the day it would split up and dissipate."
Until then, Gingrich and the Tea Party could very well be "Tebowing" come the Iowa caucuses.


text:
Let's face it, craft beer is delicious and the freshest beer is on tap!
Through a fondness of craft beer and a frustration of the mechanics involved to pour it, the Beer Dudes bar float project was created!
Our mobile bars here in Perth, Western Australia are re-born horse floats from the 1970's. Lovingly stripped back, sanded, sprayed and fitted with the most hi-tech beer dispensing equipment available.
Now, we can bring the best bar to you. Fully licensed and stocked with FIVE TAPS OF CRAFT BEER & CIDER, LOCAL BOUTIQUE WINES and HAND-CRAFTED SPIRITS !
"Before, when we joked about having to haul everything by horse and cart we didn't think we would actually be doing it!"


text:
MOVIE SYNOPSIS [ General Audiences ] With the main performance of Elizabeth Huett, this film directed by Ryan Polito was premiered in cinema or TV in 2010. The film "Taylor Swift: Speak Now" had an original production of USA. You can watch Taylor Swift: Speak Now online on TV cable or theaters with original audio in English at different dates. This film premiered in theaters in 2010.
Rating: 5 by 126 users./
Runtime: 60 minutes
Elizabeth Huett, Dominique Kelley and Taylor Swift.
60-minute film (full movie) directed by Ryan Polito.
The original audio of Taylor Swift: Speak Now has dialogues in Dolby Digital, it was produced in USA.
It premiered in cinemas or television in 2010.
Jamison Rotch, Taylor Swift, Todd Cassetty and Jillian Ellis.
This film was produced and / or financed by Todd Cassetty Welding Service.
National Broadcasting Company (NBC).
Without commercial breaks, the full movie Taylor Swift: Speak Now has a duration of 60 minutes; the official trailer can be watched in streaming on the Internet. You can watch this full movie free in EnglishDolby Digital in movie TV channels, renting the DVD or with VoD services (Video On Demand player, Hulu) and PPV (Pay Per View, Netflix).
See the page of this full movie, Taylor Swift: Speak Now in FULLTV Movies.


text:
|Home | About | Journals | Submit | Contact Us | Français
We conducted a systematic review to evaluate characteristics of human papillomavirus (HPV) testing, particularly Hybrid Capture 2 (HC2), in follow-up after treatment for cervical intraepithelial neoplasia (CIN) for detection of residual or recurrent CIN grade 2 or worse.
MEDLINE was searched for relevant studies published between 1992 and September 2007. Of the 1,107 citations identified, 20 met inclusion criteria.
Studies using polymerase chain reaction (PCR) testing were too heterogeneous to combine. We identified 5 studies that performed both HC2 and colposcopy. Pooled sensitivity for HC2 was 90.7% (95% CI: 75.4%–96.9%) and pooled specificity was 74.6% (95% CI: 60.4%–85.0%). Pooled sensitivity for cervical cytology was 76.6% (95% CI: 62.0%–86.8%) and pooled specificity was 89.7% (95% CI: 22.7%–99.6%).
HC2 testing can identify about 91% of women with residual or recurrent CIN 2 or worse, but about 30% of women in follow-up would undergo colposcopy.
Guidelines from the American College of Obstetricians and Gynecologists (ACOG) and from the American Society for Colposcopy and Cervical Pathology (ASCCP) include testing for oncogenic types of human papillomavirus (HPV) as an acceptable strategy for surveillance after treatment of cervical intraepithelial neoplasia (CIN).1, 2 Published literature about the use of HPV testing for this purpose, however, is relatively limited. Prior reviews of HPV testing after treatment for CIN have included studies using two different techniques for HPV detection, polymerase chain reaction (PCR) and hybrid capture.3–5 Systematic reviews of HPV testing for primary screening were conducted in a different context, in which risk of CIN and the tissue architecture of the cervix differed from that of women after treatment. Drawing conclusions about the overall body of evidence, therefore, has been challenging.
PCR selectively amplifies HPV DNA, increasing the viral sequences in the sample. PCR techniques vary and studies may include a varying group of selected oncogenic types. Hybrid Capture 2 (HC2) identifies thirteen oncogenic HPV types (16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, and 68) by detecting HPV DNA-RNA hybrids formed from the sample and captured by antibodies.6 Hybrid Capture 2 is the only HPV test approved by the Food and Drug Administration for commercial use in the United States. Hybrid Capture 1 (HC1) is an earlier version of this test and is no longer available. Test performance characteristics (sensitivity and specificity) of PCR testing have been shown to differ from those of HC2 testing in studies of HPV testing for primary screening.7
Three published systematic reviews have examined HPV testing in the context of post-treatment follow up of CIN.3–5 One review noted "marked heterogeneity in the design, population, intervention and follow-up policy across different studies".4 Indeed, all three systematic reviews included prospective and retrospective studies and studies using PCR methods as well as HC2 methods for HPV detection. Despite this heterogeneity, these reviews provided pooled estimates of sensitivity and specificity without regard to the number of different HPV types tested for or the HPV detection technique employed. Since the publication of these reviews, data from three studies on HPV testing and recurrent CIN have been published: one relatively large study8 and two smaller studies.9, 10 These new publications add substantially to the body of evidence for post-treatment HPV testing.
We conducted a systematic review and meta-analysis to determine the test characteristics of HPV testing for post-treatment detection of residual or recurrent CIN grade 2 or worse. More stable estimates of test-specific characteristics in this context will allow for the evaluation of potential outcomes of different testing strategies.
We searched MEDLINE for relevant citations from January 1, 1992 through September 20, 2007. Three search queries were used (Appendix). All searches were conducted independently and their results were combined with duplicates removed. References identified from either search were candidates for further review. We also searched reference lists of review articles and of articles identified through our search for additional citations. Since this study was a systematic review, it was considered exempt from review by the University of California, Davis, Institutional Review Board.
Identification of relevant studies was conducted using a multi-step process. The titles of the full list of citations were reviewed for relevance by two reviewers. Abstracts of citations with potentially relevant titles were then reviewed by two reviewers. At the final step, the full text articles of the abstracts deemed relevant were reviewed for inclusion in the systematic review.
We included studies in which women were treated for any grade of CIN by conization, loop excisional procedures, laser ablation, or cryotherapy. All participants had to have had HPV testing within 12 months of treatment and a minimum of 12 months of follow-up. For a study to be considered for pooling, we required colposcopic evaluation with biopsy (when applicable) of all positive results in all women to determine the proportion of women with and without disease post-treatment. The histological distinctions between CIN 2 and CIN 3 are poorly reproducible according to current guidelines, which use CIN 2 as the threshold for treatment.2 Therefore, we chose CIN 2 or worse as the clinically important outcome rather than the more stringent criteria of CIN 3 or worse. In studies in which cytology was also performed, we used a threshold of atypical squamous cells of undetermined significance (ASCUS) to define a positive result since guidelines suggest this threshold for referral to colposcopy.11 Studies that had incomplete reporting of outcomes and interim studies with data included in a later report were excluded. We also excluded studies with more than 30% loss to follow-up.
The literature search identified 1,107 citations (Figure 1). Of these, 1,002 were excluded as not relevant by their titles. After review of the abstracts of the remaining 105 citations, a further 42 were considered not relevant and 63 underwent full text review. Among these, 20 studies were deemed relevant to the topic and met methodological criteria. Among the 43 excluded studies, 32 did not address the research question and 11 had methodological limitations that precluded them from inclusion. The limitations included unspecified treatment,12–16 less than 12 months of follow-up,17–19 follow-up HPV test not done,20 loss to follow-up >30%,21 and colposcopy or biopsy not performed to confirm the diagnosis of recurrence.22
Data were abstracted from full texts by two reviewers (JM and either BC or RA). Discrepancies were resolved by consensus. When the data presented in the published studies were ambiguous or missing, we contacted the corresponding author. Abstracted study characteristics included country and year of study, study design, initial and final sample sizes, mean or median age and range, type of initial treatment, type of HPV test (HC1, HC2, or PCR) and viral types included (for PCR), findings from HPV testing, cytology, colposcopy and biopsy, and mean or median length of follow-up and range. Quality indicators abstracted included blinded assessment and whether follow-up was influenced by HPV test results.
The relationship between HPV positivity and CIN grade 2 or worse at follow-up by colposcopy was abstracted from each study in a 2-by-2 table, which was used to calculate sensitivity and specificity. A continuity correction of 0.5 was added to cells in 2-by-2 tables with zero counts before calculating sensitivities and specificities. This continuity correction allows the use of the logit transform for meta-analysis and the calculation of variances when zero cell counts are present.23
Studies were grouped categorically according to the type of HPV test typing performed (HC1, HC2, or PCR). We reviewed characteristics of individual studies to determine whether pooling was appropriate, including assay type, HPV types included (for PCR), and whether colposcopy was performed on all subjects as a reference standard. When appropriate, pooled sensitivity and specificity were calculated using a bivariate normal model.24 The model assumes the logit transformed sensitivities and specificities have a bivariate normal distribution. The mean values for each incorporate a random effect to account for variability around the means, and hence, the variability between studies. Correlation between the sensitivity and specificity is explicitly modeled through the bivariate normal variance-covariance matrix. The bivariate normal model also incorporates the precision of the sensitivities and specificities of each study. Studies with more precise estimates are given more weight than studies with less precise estimates. 95% confidence regions were also calculated using the parameters estimated from the bivariate model.25 The model was estimated using the "nlme" package in R.26, 27
Since hypothesis tests for heterogeneity have poor statistical properties, we used the Q-statistic and the I2-statistic as indicators for potential heterogeneity.23, 28 When heterogeneity was quantitatively indicated, we further examined study characteristics for variation that may have accounted for the observed heterogeneity (e.g., age range of participants, time between colposcopy and procedure).
The 20 studies considered for review included one study using HC1 for HPV testing,29 eight studies using HC2,8–10, 30–34 and eleven studies using PCR.35–45
The 11 studies using PCR testing were highly heterogeneous in their study characteristics. First, PCR tests included a varying number of viral types, from as few as 2 types38, 39 to as many as 25.41 In addition, varying study designs were employed: 6 were prospective cohort studies36, 37, 40–43 while 5 were retrospective case-control studies.35, 38, 39, 44, 45 Few of the studies using PCR followed-up all subjects with colposcopy.37, 40, 42 These studies also exhibited quantitative heterogeneity reporting a wide range of sensitivities (29%–93%) and specificities (64%–98%). Thus, data from the PCR studies were not pooled.
The characteristics of the HC2 studies are shown in Table 1. Pooled sensitivities and specificities were calculated for the HC2 studies as this test has uniform test characteristics for a fixed set of oncogenic HPV types and it is the only HPV test approved for commercial use in the United States. Among the HC2 studies, two were excluded from pooling because follow-up colposcopy was not done on all women.31, 34 An additional study was excluded because it included only women who were referred for an abnormal Pap smear after treatment.30 Thus, 5 studies were used in the meta-analysis.8–10, 32, 33 All studies of HC2 used a positive cutoff of 1 pg/ml.
Recurrence rates of CIN grade 2 or worse, and sensitivities and specificities from the included HC2 studies are shown in Table 2. Among the 5 HC2 studies that were pooled, residual disease or recurrence of CIN 2 or worse was found in 1.1%–11.8% of women (pooled rate, 6.6%). The bivariate normal model fitted on these 5 studies estimated the pooled sensitivity for HC2 to be 90.7% (95% CI: 75.4%–96.9%) and the pooled specificity to be 74.6% (95% CI: 60.4%–85.0%) (Table 2 and Figure 2). The Q-statistic for sensitivity was 1.7 (P=0.80) and the I2-statistic was 0%. Both statistics suggest there was no heterogeneity in the sensitivities reported across the 5 studies. The Q-statistic for specificity was 20.1 (P<0.01) and the I2-statistic was 80%, indicating that 80% of the variability in the specificities across the 5 studies was due to heterogeneity. In other words, the specificities of the HC2 studies were heterogeneous. The heterogeneity was due to a relatively low specificity (63.8%) in the largest study.8 The mean age of participants in this study was over 10 years younger (24 years) than in any other HC2 study. A sensitivity analysis excluding this study resulted in a pooled sensitivity estimate of 91.7% and a pooled specificity estimate of 76.5%; neither appreciably different from the estimates when this study was included. Therefore, excluding this study did not seem necessary.
Among the HC2 studies, four included data on cervical cytology as well.8–10, 33 All used a threshold of ASCUS or worse for recurrent disease. Two of the studies used liquid-based cytology8, 10 while the other two used conventional cytology.9, 33 Combining the four studies using an ASCUS or worse threshold gave a pooled estimate of cytology sensitivity of 76.6% (95% CI: 62.0%–86.8%) and a pooled estimate of cytology specificity of 89.7% (95% CI: 22.7%–99.6%). The same four studies also included data on the combination of either HC2 positive or cytology positive, where a positive result on either test suggests referral to colposcopy and negative results on both tests suggest routine testing, which corresponds to clinical guidelines in the post-treatment context.2, 11 However, one study used an LSIL or worse threshold for cytology.8 From the three studies using an ASCUS or worse threshold the pooled sensitivity for the HC2 or cytology combination was 93.1% (95% CI: 16.7%–99.9%) and the pooled specificity was 75.7% (95% CI: 57.2%–87.9%) (Table 3). This specificity was lower than for HC2 alone pooled from the same three studies (79.0%; 95% CI: 69.3%–86.2%).8
For the surveillance of women after treatment for CIN, summary evidence indicates that 90.7% of women with residual or recurrent CIN 2 or worse can be identified by HC2 testing. Hybrid Capture 2 combined with cytology offers greater sensitivity (93.1%) than either test alone, but a somewhat lower specificity to HC2 alone (75.7%). Compared to the previous reviews of HPV testing after treatment, which pooled studies of PCR and HC2 testing without a common reference standard,3, 5 our approach yielded a similar value for sensitivity to that found by Zielinski et al,5 but lower than that found by Arbyn et al.3 The pooled specificities of both previous reviews were similar to ours. Women with a history of CIN are at higher risk for future CIN, and cervical treatments may change cervical architecture, potentially hindering adequate sampling and leading to decreased test sensitivity. However, our estimate of HC2 sensitivity was similar to that observed for HC2 in primary screening settings (90.7% versus 90.0%). Our estimate of pooled specificity, however, was considerably lower (74.6% versus 86.5%).7
The clinical implications of our findings are shown in Table 4. Given the mean prevalence of residual or recurrent CIN 2 or worse in the pooled studies of 6.6%, our findings indicate that in a theoretic cohort of 1000 treated women, 66 would have residual or recurrent disease. Assuming our summary estimates reflect a true difference in test accuracy between HC2 and cytology, using cytology surveillance, about 15% (n=147) would be referred to colposcopy, and 51 of the 66 women expected to have CIN 2 or worse would be identified. Using HC2 surveillance, about 30% (n=297) would be referred to colposcopy and 60 of 66 expected cases of CIN 2 or worse would be found. In other words, with HC2 testing, twice as many women would undergo colposcopy to identify 9 additional cases of residual or recurrent CIN 2 or worse for every 1000 women in post-treatment surveillance. In this setting, it seems prudent to offer a highly sensitive test; however, the impact of this clinical decision on the use of healthcare resources and the anxiety and discomfort resulting from extra procedures for women must be considered.46–49
The sensitivities reported in the studies of HC2 did not exhibit quantitative heterogeneity, however, the specificities did. The study that contributed most of the heterogeneity to the estimate of specificity was the largest.8 This study, which had the lowest specificity, included the youngest cohort of women, with a mean age of 24 years, in contrast to the other HC2 study cohorts with mean ages between 34 and 40 years. Excluding this study from pooling did not yield appreciably different estimates. The heterogeneity found for HPV specificity in our review was consistent with the heterogeneity found in a review primary screening studies, which also found lower specificity among younger women.50
Our findings are limited by the quantity and quality of available published studies addressing the properties of HPV testing for evaluation of women after treatment for CIN. We did not attempt to locate or include unpublished studies. We were not able to control for differences in patient populations between studies (such as time from treatment to first HPV test, sequential positivity and negativity, or HPV type) because of the small number of studies or lack of uniform reporting of such information; however, we did conduct a sensitivity analysis. Despite these limitations, our review of HPV testing after treatment for CIN applies the most rigorous methods of reviews published to date. Limits on current knowledge are highlighted by our findings, including the lack of randomized controlled trials comparing follow-up strategies and the limited number of studies applying a reference standard test (colposcopy) for all patients. Among those five studies that met our standards for pooling, the largest included 485 women and most were considerably smaller, while the longest mean follow-up time after treatment was only 24 months.
Recent randomized trials of HPV testing for primary screening have suggested that the higher sensitivity of HPV testing for CIN 2 or worse leads to earlier detection of these lesions and lower rates of abnormalities in subsequent screening rounds.51–54 The most recent guidelines addressing follow-up of women after treatment for CIN include HPV testing alone at 6–12 months as an initial follow-up strategy to determine whether women can return to routine screening beginning 12 months after treatment.1, 2 While a highly sensitive test may well be appropriate to detect recurrent CIN after women have undergone treatment, a long-term follow-up study of women in Sweden treated for CIN 2–3 that applied HPV testing retrospectively to archived specimens found that HPV testing 3–24 months after treatment had poor sensitivity (24%) for predicting risk of recurrence beyond 2 years.45 Initial follow-up with colposcopy in this setting offers an alternative as a highly sensitive but more costly test.55
Our findings suggest that policy recommendations for follow-up of women after treatment for CIN may have moved faster than the ability of current scientific evidence to define the most beneficial strategies. Ideally, a randomized, controlled trial comparing HPV testing to cytology, and perhaps to colposcopy, with follow-up over a period of at least five years, would be performed to clarify the best approach, and permit evaluation of the impact of both false-positive and false-negative findings. Alternatively, a large prospective cohort study with standardization of diagnostic tests and performance of a simultaneous reference standard (e.g., colposcopy) with follow-up over an extended period of time would provide important information. Until such data are available, cost-effectiveness and cost-utility models of available observational data will be valuable in determining surveillance strategies that maximize benefits and minimize harms.
Hybrid Capture 2 identifies 91% of the small proportion of women with post-treatment residual/recurrent disease, but 30% of women will test positive and need colposcopy.
Financial support This research was supported by the National Cancer Institute grant 1R01CA109142
Previous presentation of findings Preliminary results from this study were presented as a poster at the North American Primary Care Research Group (NAPCRG) 2007 annual meeting, Vancouver, BC, Canada, October 20–23, 2007
Conflicts of interest to declare: None
PubMed Central Canada is a service of the Canadian Institutes of Health Research (CIHR) working in partnership with the National Research Council's national science library in cooperation with the National Center for Biotechnology Information at the U.S. National Library of Medicine(NCBI/NLM). It includes content provided to the PubMed Central International archive by participating publishers.


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Day 88 (2): The kindness of strangers
Shing Travel Blog› entry 124 of 260 › view all entries
Thanks to the people I met here and/or travelled with: Tim & Wim (Belgium)
With only a few more hours of daylight left we wanted to try and reach the Margozur lakes. This is a 20 kilometre string of seven turquoise mountain lakes, accessible by a winding gravel road. Progress was slow, but the views were stunning. Since there are no road signs in this area of the country we had to stop a couple of times to ask for directions. At one point we stopped near a mine where about 7 mine workers stood by the road side. We asked "Shing" and they nodded yes and got in the car. Err, wait, we asked them for directions and they thought we offered them a lift... Ah well, the car can handle it. Officially it is only licensed to carry four people, but heck, no one's going to bother in this country, now are they?
After Shing the road got really bad.
We had planned to camp at one of the seven Marguzor lakes, the fourth lake was recommended to us by the lady at the tourist office. However, as darkness fell it became increasingly difficult to find a spot to camp. There wasn't really anywhere. I mean, there was just a mountainside, a road and water. That was it. Nowhere was wide enough to park by the roadside and stay for the night. To make matters worse we were unsure whether we had reached the third or fourth lake. I did see something which looked like a flat spot of land, with a house or car parked in between two lakes, but in the darkness we completely missed the turn off (we saw it on the return trip the next morning).
We drove into a little village (which we later identified as "Nolfin") and decided to stay here for the night. After we parked the car Wim went over to the nearest house to double check if it was ok to camp in the middle of the road. The man who lived at the house immediately invited us over. He had a separate guest room in his small, one-story mud-brick house (or maybe this is where the family usually slept) and immediately he offered it to us to stay the night here. We were unsure, we could easily sleep in the car and certainly didn't want to be a burden or exploit the people's hospitality.
As we sat down on a shyrdak (thin mattress) on the floor and we were served tea. After tea came more tea and then bread and bowls of something which is best described as the watery by-product of Feta cheese.
The man kept insisting that we'd spend the night in this room, rather than sleep in the car, so we agreed. He was a lovely man even if we could barely communicate, and we feared that if we'd refuse we would insult him.
So we slept quite comfortably on a pile of mattresses, underneath an even larger pile of blankets, while the family slept in the room next door. It was quite cold at night, in fact. After almost two months in the desert and desert-type climate I had forgotten what it was like to be cold.
What a great first day in Tajikistan!
The next morning we were treated to some more tea with dry bread. I don't think the people had much to offer us, but whatever they had they shared. We were unsure whether or not we should pay anything for our stay. It can be considered an insult to offer money, so instead we left some money in the room as we left.
It had been a very interesting experience. The man was genuinely hospitable and while I have met hospitable people before, this was the first time that a complete stranger has invited me to stay at his home within minutes after meeting him.
Unfortunately we had not met the rest of his family. His wife and daughters all wore hejab, but this was seemingly not enough.
After breakfast we drove the 63 slow kilometres back to the main road. Now we could finally see the much lauded lakes. They were truly stunning. We had indeed driven to the end of the fourth lake, so on the way back we got to see four of the stunning turquoise lakes, in which the surrounding mountains reflected perfectly.
It had been well-worth coming here, even if it took us nearly three hours to drive back to the main road. Shing was also quite a nice place to see in daylight, despite having to cross that horrible road again. But it was comforting to see there were some construction works going on. This may be a poor country and this may be a remote region where few people live, the government at least seems intend to have the infrastructure fixed again.


text: Let's try a different sort of question! 3) Which of these beverages is the cheapest? And which is the most expensive? Bottled water Milk, plain or chocolate Plum wine or sake Large soda, fountain Bonus points for the cost (±25 cents) of either answer. As usual, PM me your answers within two days, and respond to this thread. Thanks so much for playing!


text:
The genre of Naked Vlogs has just been launched in the United States.
The concept is simple: You vlog, or video blog (podcast) in the nude….
Luckily (or unfortunately, in some cases) we don't see the entire body… we just see the top half of the person.
It's an amusing idea. Will this soon be launched in the French blogosphere?
Go have a look; it is for a good cause, and your stats will go through the roof.
The initiator of the Naked Blog Campaign, Chris3ff:
And the best of Naked Vlogs:
Follow @abry


text:
Culture: Festivals
106 articles in category
Page 1 of 4, Go to page: 1, 2, 3, 4 [Next]
- Falling in Love
I wanted her to see how one could fall in love.
- Cultures That Stay Unknown
As a Bengali myself, I concentrated myself on the culture and how it is being demolished.
- Fiction: Mundane Living And Forgotten Deeds
Ironically her balding head reminds me of my girlfriends young pink skin peeking through the mousy pubic hair.
- Cut Loose All The Flying Kites
Many understand why the government deems it necessary to wage this war against the harmless kite, but everyone still wants it.
- Fiction: The Winning Point
Vineet was an ordinary young man with one remarkable talent that came to fore only in his late teens in college. It all started with
- Photo Essay: Moon Struck
Some photographs of the biggest full moon of 2010.
- The New Year Post
At times, it seems the process of New Year wishing has become so mechanical.
- poetry: long live god
An overwhelming wave of insensitivity and insulation that wraps and warps our perception of suffering.
- Do Festivals Mean Anything Any More?
I feel that with the changing times, we should revamp the way in which the festivals are celebrated
- For God's Sake
Pray because you believe, and then ask him for what you want.
- Vidyaarambham : Initiating Children to the World of Knowledge
The writing on rice grains symbolizes acquisition of knowledge that leads to prosperity.
- Satire: Super-califragilisticexpiali-stitious
The members of the association of Progressive Indian Women (Bharatiya Unnatisheel Mahilayen a.k.a BUM) were livid with rage.
- Ekadantaya Dheemahi
This is Baba Bangali bringing you yet another spicy interview with my drinking buddy and fellow food lover Gunny Bops.
- Mumbai Queer Azadi Pride 2009 - The Right to be Happy
"If it is Love, God wouldn't mind; there is enough Hate in this world"
- Wordfest 2009, Grahamstown Festival, English Museum, Performance Poetry, Pritish Nandy, and More
Performance Poetry at Grahamstown Festival, South Africa 2009.
- A Postmodern Wedding
Occasionally our cultural climate doles out opportunities to compensate for the cinematic inadequacy of our lives.
- Diwali Dreams: Kal Aaj Aur Kal
Lots of shrieks, emotional reunion. Tears on everyone's eyes.
- Why Do We Have a National Holiday on Christmas and Good Friday?
Does anybody have a clue why we last Friday was a National Holiday?
- Jamshedi Navroze: Parsis welcome the Spring
In India, it is another day for us Bawas to party and eat and drink - as if we ever need a reason.
- The Magic of 'Pata Chitra'
'Pata' in Sanskrit means piece of cloth and 'Chitra' means painting or picture.
- If the World Becomes Colour Blind...
The importance of colors in our life. Is Holi this year really worth celebrating ?
- My Funny Valentine - Sweet Comic Valentine
None of my funny Valentines expect rings or a gift, much less a flower bouquet for Valentine's Day.
- Valentine's Day: Love Expressed On Desicritics
Love makes us pause and smell the roses, enjoy the caress or maybe for once realize that we have much to be grateful for no
- Bazaar Walks: Today at Dadar
I went to Dadar Market today, to chalk out a new Bazaar Walk tour. Heres what I came away with.
- Devi Comes Home
The Kalash, symbolic of the universe (Brahmaand), represents the Devi, during these nine days.
- Could India Host an Impressive Olympics?
Could India hold an Olympics that would flatter, rather than embarrass the nation?
- Idol Immersion Increasing River Pollution in India
There are a number of areas where modern science and problems clash with traditions.
- Travel Report: Korba Street Festival - Heliopolis, Cairo
What I got to see, kind of reminded me a bit of the Kala Ghoda festival in Bombay, but just a little bit.
- Putrid Pilgrimages in India
The provocatively titled blog The Shit of the Saints is Still Reeking talks of the 2007 mela in Allahabad.
- A Goddess for Summer
In Mumbai, a small community from Andhra Pradesh worships the Goddess Mariamman every summer, seeking protection from the dreaded pox.
- Photo Essay: I Love Beauty Parades
The story of beauty pageants and why i love them.
- Holi - Not My Kind Of Festival
We didn't mind a little gullal but the violence had to stop.
- Religious Convergence on March 21st
A once in a lifetime occurrence when "half the world's population is going to be celebrating something" falls this Friday
- Kambala: Racing Buffaloes, The Slushy Way
A day at Kambala, an action packed buffalo racing sport in slushy waters.
- The Demise of the Joker - India's Vanishing Circus
The 130-year-old Indian circus industry, once the favorite form of entertainment with family and friends, is struggling to survive.
- Do You Know Your ABCDs?
While living in India some youngsters ape the Western lifestyle and upon arriving in the United States label those born and raised here as "confused".
- Thyagabrahmam - Celebrating the Great Saint Thyagaraja
Irrespective of the seniority or popularity of musicians, every musician pays tribute to Thyagaraja by singing his Pancharathna Krithis
- Pongal - An Ancient Harvest
The rural festival has become yet another urban shopping fest
- Is The Guardian Seeing Pink Elephants?
It is inexcusable when a popular media form chooses to propagate cultural ignorance.Aditi Nadkarni
OPINION | Culture: Society, Culture: Social Issues, Culture: Religion, Culture: Magazines, Politics: Censorship, Politics: Freedom, Politics: India, Politics: Religion, Culture: The Writing Life, Culture: Travel, Culture: Holidays and Observances, Media: Journalism, Media: Magazines, Media: Internet, Media: Newspapers, Media: News, Culture: Desi, Culture: Education, Culture: Festivals, Politics: Peace
- Margazhi and Music
The Margazhi Music Season is something to be experiences atleast once in one's life...
- Photo Essay: Christmas in Kolkata, India
The streets are lit up, and the crowds are around & about.
- Photo Essay: Merry Christmas Wishes
I was most amazed by the buoyancy, the delicacy and the irrepressible liveliness and good spirit that rule the atmosphere.
- An Impromptu Review of the Konark Dance Festival
Longwinded felicitations are the order-of-the-day at the Konark Dance Festival. Even I was compelled to join in the blather!
- Make A Difference This Christmas
Go on - make a difference for someone this Christmas!
- Star-light and Angel Song
In a world of violence and war, Christmas re-kindles hope in me.
- Christmas Beyond the Manger
The anti conversion laws have been termed anti constitutional by NCM as it violates the fundamental rights provided by Indian Constitution.
- Poetry: Say NO to Thanksgiving!
One Turkey's Call.
- What is Thanksgiving?
Each one of us can become a voice to others to encourage whatever talent we may have.
- Mothers Who Die And Wives Who Fast
Marriage is our highest calling, and family, motherhood and ma are sacred archetypes.
- An Uneven Balance
I find it impossible to go the distance to a mere recreation of a festival that feels meaningless without the cultural and social context.
- Nine Days of Festivals
A photo-essay on Navrathri and Dussehra
- Mysore Dussehra: Thank God, it's over
The point here is, my niece was denied admission even after compliance with the handbag ban.
- Rama in Tamil Tradition
The Sangam corpus is typically used as a reliable source for a lot of historical information about Tamil Nadu.
- Book Review: Ganesha Goes to Lunch by Kamla K. Kapur
Myths by their very nature appeal to the heroic, and the virtuous elements of our being.
- Dasara, Mysore, & Green Activism
It may be that anti-Chamalapura agitators do not see an issue in Dasara lightings, as I do. Or perhaps, they have an issue with nerves,
- The Bygone Days Of Ramleela
Memories around the Ramleela days
- The Moon Sighting Controversy: Should Muslims Really Have One Eid?
Eid is being celebrated across the Muslim world on three different days. Should we have it one day instead?
- Globalising Mysore Dasara
People dont talk of Dasara without a mention of Mysore. But how many make it their destination when they plan their Dasara holidays;
- India Should Host an Annual Paganfest
Who wouldn't want to listen to a good Prakrit punk rock number praising Soma?
- Stop Torturing Rama
In the end, I can only be amazed at the tizzy over Rama/Ramayana in public discourse.


text:
Airline: Nationwide
Aircraft: Boeing 737-200 ZS-PIV
This flight formed part of my overall route back to Amsterdam via London Heathrow. George Airport has been undergoing some upgrades, a larger arrival and departures hall mainly and they are going to upgrade the restaurant area as well. There are more airlines serving the airport since I was last in George three years ago. Currently South African Express, Comair, Nationwide, Kulula and 1time all serve George.
As the airport is relatively small boarding is always pretty quick, our plane was parked at the end of the ramp.
While walking towards the aircraft I saw an HS748, the livery made it abundantly clear who the former operator was:
|No prizes for guessing the former operator!
I was seated right behind business class so great leg room, made for a comfortable flight!
The service was very good, we were given a sandwich with chicken,mayo and apple and cheese filling, not bad. As we were just about to touch down, literally like 2 metres of the runway, a little kid behind me said to his mum, "that was a good landing wasn't it mummy?" to which the mother replied: "we haven't even landed yet!"
Nice bit of inflight humour for you there!
Johannesburg is a top airport, the domestic terminal alone puts many European and North American airports to shame. They are currently extending the International terminal for extra capacity, probably in time for the 2010 World Cup!
All in all, I would definitely fly Nationwide again, I am interested to try out their international service to London. Its a shame South African Airways has stopped flying its 737-800s to George, however it was great to fly a classic.
Regards all,


text:
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Independent trust, fund, real estate and corporate services provider First Names Group has promoted Karen O'Hanlon to managing director of its Singapore business.The appointment is effective immediately.O'Hanlon will lead the team in Singapore, continuing to build on the foundations...
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WASHINGTON, June 21 (Reuters) - U.S. oil refiners operating at lower capacity does not indicate manipulation of crude and oil product prices, despite the Federal Trade Commission's newly launched investigation into the matter, a official with the International Energy Agency said on Tuesday. The FTC said on Monday it would investigate, in part, whether U.S. refiners operating at about 82 percent of capacity in May, down around 7 percentage points from a year earlier, was an attempt to limit ...
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|18 Oct 2011
I been waiting for mine for 6 days now ..they are telling me I will get it within 30 days ...
Its faster than my current 1090T and its slightly faster than than an 1100T... thats all I really care about..
I am having problems with my current 1090T because it cant multi-task very well with 3Ds Max, Zbrush 4, Photoshop CS5... running together... my system gets bogged down running all those at once even with 16gigs of ram..
I HOPE that this Bulldozer will be able to handle it better...
|My System Specs
|18 Oct 2011
Windows 7 Ultimate x64
|My System Specs
|18 Oct 2011
CPU: AMD FX-8150 @ 3.6Ghz/4.5Ghz Turbo socket AM3+
MB: Gigabyte GA-990FXA-UD5 socket AM3+ (F6 BIOS)
RAM: 16GB CORSAIR Vengeance DDR3 1866mhz (9-10-9-27-1T timings)
Graphics: CrossfireX 16x/8x HIS IceQ X Turbo HD6950's(both are stock OCed at 840/1280mhz) , 2 gig GDDR5 cards 11.10v2 drivers
64GB PLEXTOR PX-64M2S SSD (SATA3) <--OS drive
128GB PLEXTOR PX-128M2S SSD (SATA3)<--OS drive
1TB SAMSUNG HD103UJ (SATA2 on a SATA3 controller)
120GB OCZ_RevoDrive x2 RAID SSD (PCI-E 4x)
Samsung CD/DVD/Blu-Ray ROM/Burner (SATA on a SATA3 controller)
Sound: Onboard Realtek ALC889 7.1 channel connected to 70 watt Philips 2.1 speaker system
Power Supply: Kingwin 1000watt modular
Case: Cooler Master 932 blue
OS: Windows 7 64bit Ultimate SP1 dual boot with Windows 8 64bit Preview
17" LCD left , 24" LCD Middle, 17" LCD right (24" screen just in case a game don't like eyefinity, I can change it to 1920x1080)
CPU cooling: COOLER MASTER Hyper 212 EVO with one 120mm and one 90mm fan, with Arctic Cooling MX-4 Thermal Compound
Im not worried about gaming.. we will see how the benchmarks go, I already heavily benchmarked my 1090T and saved the results for a comparison..
|My System Specs
|20 Oct 2011
Windows7HOMEPREMIUM (x64)- bit
Graham Clark
? If the BullDozer is So Bad anyone have say A Intel XEON or 2 to go head to head to Benchmark just as a curiosity Measure?
|My System Specs
|21 Oct 2011
So far the first test (SiSoftware Sandra 2011 SP5)..shows Bulldozer is faster than a 1090T, but weak in .net performance:
EDIT: Second test vs other computers even an I7 2600k:
3rd test: Test used: Passmark performance test 7 64bit ..CPU Mark
My FX-8150 scored a 9,555.0
Its higher than the FX-8150 on the chart here:
But it cant reach the I7-2600K with a score of 9,986
But still this FX-8150 is performing well so far
|My System Specs
|26 Oct 2011
Windows 7 Professional 64 bit
To make matters worse, the 8150 were due to be instock at most places in the UK yesterday and for some reason non of the major suppliers have had their stock in.
I believe one site is now stating it will be a few more weeks before they receive any stock.
Are they available in any other countries yet?
Not the best of starts at all really.
|My System Specs
|26 Oct 2011
We have 4/6 and both Eight's in stock here in the states! But many have low inventories or are out of the 8150's.
|My System Specs
|26 Oct 2011
Windows 8 Pro x64
I'll just sit back and enjoy the performance of the Core i7s in my desktop and laptop (both are quads).
Not a surprise though... I think it's largely Intel's HyperThreading tech that's doing AMD in. I've disabled HT once to see how much it would affect performance for me, and it had quite an impact.
|My System Specs
|28 Oct 2011
I'll just sit back and enjoy the performance of the Core i7s in my desktop and laptop (both are quads).
Not a surprise though... I think it's largely Intel's HyperThreading tech that's doing AMD in. I've disabled HT once to see how much it would affect performance for me, and it had quite an impact.
Most games run perfect on it ...except Deus EX: HR ...it crashes with a blue screen error and the computer resets...
|My System Specs
|Thread Tools
|Similar help and support threads
Look out Bulldozer, here comes Excavator!
16 cores? Able to leap i7's in a single thread. In 2015
|Hardware & Devices
My new Bulldozer has shipped.
I will be joining the ranks of the 8 core processor group. Got great advice from a fellow member here on which model to go with. Looking forward to maximizing my ram's potential and getting a nice overclock on this beast. From what I'm reading users are reporting fantastic results and this chip I...
|PC Custom Builds and Overclocking
So, Bulldozer was a disappointment. What now?
Should I get a Phenom II X6 1090T or an FX-8120? I don't have to get one or the other, but I'm not going to buy an Intel CPU. Not yet anyway...:mad:
|Hardware & Devices
More details on AMD Bulldozer
More ...
|Hardware & Devices
What do you guys think of this Bulldozer MB ?
Hi ,Everyone one of my fav stores has finally gotten the Bulldozer mainboards in . I was looking around most of them start out at 199.99 I found one cheaper by 50.00 us check it out compared to the extreme one's i seen FRYS.com | ASUS
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The Bulldozer is coming !
Here you go boys and girls. AMD is going to rock the house with 8 cores, like Windows 8 I can't wait ! https://channel9.msdn.com/Shows/InsideXbox/E3-2011-AMD-and-the-new-eyefinitiy-technology The chip news is at the end of the video....FYI !
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I know Windows 7 retail .iso files can be downloaded from here (digital river).
I assumed Windows Vista likewise could be downloaded from here (digital river). However it doesn't works for me, says denied... I assume it used to work and now doesn't.
Does anyone know of a legitimate source where I can download Windows Vista 32 bit .iso files (hopefully with SP2 included) without using a torrent?
Philip Yip
Windows Reinstallation Guide and Related Wikies See here for other wikies such as Customising and Using Windows 8.1, Dell Wireless Cards and Unofficial Drivers.
Thank you for using the Dell Community Forum.
I do not know where to get this download other than a torrent if Microsoft doesn't have it on their download store.
Social Media Support#IWork4DellDell Support VideosDrivers and DownloadsDriver order


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Features That You'll Love
Open 24/7, Earlybird Laundromat in Teaneck, NJ offers over 100 washers and dryers, free Wi–Fi, and lots of extra seating. Relax in front of a big screen TV or enjoy a drink or snack as you wait. Who says doing laundry has to be boring? Save time. Save money. Get the best wash.
- Open 24 hours / 7 days per week
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We are located on the corner of Tryon Road, next to Family Dollar.
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(20 lb washer only; 5am to 3pm)
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From the Blog
Preserve the Life of Your Jeans
Got a favorite pair of jeans? Here are seven simple steps plus one golden rule for keeping them fresh.Read More
Freshen That Lid —
Who doesn't have a favorite baseball cap? Keep yours fresh and clean with these tips.Read More


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Our Curriculum
Our faculty created a curriculum recognizing the diverse interests of students pursuing a career in social work. We offer a full-time course of study only for advanced standing and traditional students. Our foundation-year curriculum, with its emphasis on generalist knowledge, values, and skills of social work practice, prepares you for advanced study. Our concentration-year curriculum coursework, which allows you to select electives in your area of interest, will help you develop strategies to meet the needs of diverse clients and communities. Students enter the program in the Fall semester only.


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Key Reasons Why Your Library Should Subscribe to Wiley Online Journals
Wiley's Online Journals are available on Wiley Online Library (wileyonlinelibrary.com), an extensive multidisciplinary collection of online resources covering life, health, social and physical sciences, and humanities. A leading online repository for peer-reviewed content, it hosts more than 5 million articles from 1,500 journals.Ā Access to all abstracts and searching is free and full content is available through subscriptions and licensing agreements.
In addition, Wiley Online Library is home to more than 14,000 books, hundreds of multi-volume reference works, Wiley Interdisciplinary Reviews, more than 15,000 laboratory techniques and procedures through Current Protocols, and multiple clinical databases including The Cochrane Library.
Benefits for Researchers
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Wiley Online Library connects you to the information you need, when and where you need it. Additional benefits include:
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UK authorities 'refusing to investigate Russian money'
The UK authorities are refusing to investigate evidence of tens of millions of pounds of "dirty" Russian money being laundered through British firms and banks, MPs have been told.
Former hedge fund boss Bill Browder said that, over the past five years, he had lodged six complaints with law enforcement agencies relating to 30 million US dollars (£20 million) of stolen funds - but in each case they had refused to act.
Giving evidence to the Commons Home Affairs Committee, Mr Browder - who became a leading anti-corruption campaigner following the death of his lawyer Sergei Magnitsky in a Russian prison cell in 2009 - said there was a "general political feeling" people did not want to "rock the boat".
"Every single time we have filed a complaint, nobody has responded. They have always found excuses not to investigate," he said.
Mr Browder said that the money coming into the UK was linked to a 230 million US dollar (£160 million) tax refund fraud on his Russian Hermitage fund which Mr Magnitsky had uncovered before his death.
But while 11 other countries - including the United States, France and Switzerland - had opened criminal cases into the stolen funds, in the UK the Metropolitan Police, the Serious Fraud Office, the National Crime Agency and its forerunner, the Serious Organised Crime Agency, had all refused to investigate.
"I think this country is levitating off the flow of dirty money," he said.
"If that money was stopped, I think that certain people would find themselves without businesses and I think those people have some political influence. I can't explain it any other way.
"I have been to France, I am working very intimately with the French police, I am working with the Department of Justice, I am working with the Luxembourg police.
"I think there is a general political feeling that you don't want to rock the boat. So many people benefit from that dirty money here, it is a politically toxic issue to address.
"If there are a lot of businesses that are effectively surviving off the back of this money that wouldn't survive otherwise and they have friends in high places - these people are very close geographically to this House here - they're going to say 'Don't do that'."
Mr Browder said that he believed the total sums being laundered through the UK ran into the "hundreds of billions of dollars".
"There has been an orgy of spending on luxury goods - properties, yacht charter, couture dresses," he said.
Much of the spending had concentrated around Belgravia, Knightsbridge, South Kensington districts of London - while properties had been bought up in the "fanciest parts" of the city including St John's Wood, Hampstead and Chelsea.
He added: "If they open up a UK company for example and use then it for money laundering at a UK bank, the next destination will say that money has come from Britain which is a legitimate, normal country.
"This is a perfect cover for laundering money because we don't investigate it in this country, we don't prosecute and it appears legitimate."
A spokesman for the National Crime Agency said that it treated allegations of money laundering with the "utmost seriousness".
"We have received material from Hermitage Capital which is now being actively reviewed. For operational reasons it will not be possible to confirm details of any investigation that may result," the spokesman said.


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Wessex FM News
Portland Fire Started By A Candle
6:42am 25th September 2014
A man has been treated for smoke inhalation after a fire on Portland which was started by a candle.
Fire crews were called to the property in Fortuneswell around 11.30am yesterday morning.
The fire was out on arrival and crews took a man out of the property who was treated by paramedics at the scene.
It's thought the fire was started by a candle falling over on a wooden chair.
Dorset Fire & Rescue Service say this is a strong reminder to take extra care when using candles.
Sign up for the latest local news direct to your inbox


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2013 Better Living Show
Blue Home...
Jim Field with Progressive Builders Northwest and GHID partnered again this year to build and design the Blue Home.
The Blue Home promises to deliver energy efficiency, cost savings and high-performance features you would expect in a home with natural gas. Walk through the home and unlock beautiful design concepts and the latest home products to fuel plans for your next home makeover.
Learn how you can make changes, large and small, to reduce your home's energy use and carbon footprint, while improving the comfort, quality and livability of the space you call home. Enjoy the aromas from the gourmet kitchen, relax in the living room in front of a cozy, high efficiency fireplace, rest easy in our beautifully appointed guest suite and bathroom, and learn how to use hot water to heat your home.
NW Natural's Blue Home is built in partnership with Garrison Hullinger Interior Design and Progressive Builders Northwest, along with many other amazing local product suppliers and service providers.
Three day consumer show that is not just targeted at the early adopters of a sustainable lifestyle, but one that specifically targets a mainstream audience as well. A show that encourages everyone, no matter where they lie on the spectrum of sustainable living, to take one more step towards a healthier lifestyle. Quite frankly...we want to help make a bigger choir! We have chosen to be a free admission event to ensure that access to the resources and services at the show are accessible to all. We also provide complimentary booth space to a number of nonprofits as part of the show's efforts to encourage our attendees to become more engaged in the community. Together, we can support social change.
Last Year's NW Natural Blue Home
I've always been a huge fan of watching any process unfold, particularly when it comes to a creative process, so I wanted to give you guys a behind the scenes look at what went into planning for a Better Living Show and Blue Home last year - pretty cool stuff. Hopefully, you'll get inspired and excited about this weekend's Better Living Show and Blue Home, and be eager to see what GHID has done this year!
Front door and decorative paint...
Getting creative...
Making The 2012 Blue Home...
Before The Show Starts
Kitchen and appliances...
This is what the GHID booth looked like last year...
Now that you've been able to see some of what GHID did for the 2012 Blue Home, make sure to stop by our booth to learn more about GHID services and the products we sourced in the Blue Home! Also, we encourage you to come to the Better Living Show geared with everything you'll need to jumpstart your home projects, like photos, ideas of home projects and our staff will provide you with a 30 minute complimentary consultation to get your project in motion!
Helpful questions that Garrison suggests that you come prepared to ask,
Who will be working on my project (principal, assistant to the designer or an associate designer)? How do you handle billing (monthly for hourly fees, half down as items ordered or more)? Do you have a project that represents the same style or type of work being requested for this project? Can I see before/after photos of your portfolio? What is your rate fee structure?
Visit the Better Living Show site for a complete list of contributors to the NW Natural's Blue Home and we look forward to seeing you at the show!


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A HORRIFIED Sheffield family have reacted with disbelief after a group of children - thought to be aged five or six years old - chased their cat onto a busy road where it was run over and killed by a car.
The unsupervised youngsters were playing on Woodseats Road, Abbeydale, when they started taunting the terrified animal, according to witnesses.
Alex Hall, aged 31, of nearby Buttermere Road, who owned Tabitha, said: "We are just sickened.
"What are parents doing letting children near a busy road, let alone bringing them up with the morals that chasing cats into road is acceptable?"
Alex, a delivery driver and student, first realised something was wrong when Tabitha went missing.
He, his partner Laonie, 22, and his eight-year-old daughter Isabel, distributed leaflets and stuck up posters to see if anyone had seen their two-year-old jet-black cat. Four days later a local vet, who saw a leaflet, told Alex that Tabitha had been brought into the surgery and had died.
Alex said: "I went into the vet's surgery to identify Tabitha.
"She had been brought in by the driver of the car that had hit her.
"He was apparently very upset. He had seen a group of three children, aged just five or six, chase her out into the traffic.
"They watched the car hit her and then they ran off.
"We are very upset. Tabitha was very much part of the family. My partner Laonie is in tears and my daughter is very upset.
"People should know what has happened.
"We want the police to find these kids and speak to them, so it doesn't happen again."
A South Yorkshire Police spokeswoman said officers were aware of the incident.
Anyone who saw youngsters playing on Woodseats Road on Thursday August 18, at 5.45pm, should call police on 0114 220 2020.


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Will.i.am, Kylie Minogue Appointed Coaches for 'The Voice' Australia
"The Voice Australia" is changing things up for its third season as the show's original coaches, Seal and Delta Goodrem, won't be returning in 2014, announced the Nine Network Nine Network on Tuesday.
Instead "The Voice U.K." coaches, Will.i.am and Kylie Minogue, are coming Down Under to take their seats alongside returning judges Joel Madden and Ricky Martin. The announcement leaves Madden as the only original coach on the show, with Martin this year successfully replacing Keith Urban.
"It is an honor to join 'The Voice Australia' as a coach working alongside Kylie Minogue, Ricky Martin and Joel Madden. Australia is a highly creative country and a place with many good memories that have shaped my music career," said Will.i.am. "Australia is one of the first countries where The Black Eyed Peas enjoyed international success selling out many performances, and the place where I discovered electronic dance music. Having worked with both Kylie Minogue and Ricky Martin on past music projects, it will be fun to collaborate with them on the show."
'The Voice' Australia Expands with Robert Rigby Appointment, Kids Series to Launch in 2014
Seal, who coached the two winners, Karise Eden and Harrison Craig, in the shows first two seasons, and said in a statement that he was leaving "The Voice Australia" to concentrate on a new album and other TV gigs. "I wish all the coaches and contestants well. To my Australian fans, sorry to not be back for this upcoming season but I wanted this window of time to focus on a number of exciting career priorities – a new album, a TV and internet project and, most importantly, precious time with my children," stated Seal.
Aussie songbird Goodrem won't be leaving "The Voice" Australia family entirely -- she and Madden have been announced as the first two coaches for "The Voice Kids," which will also air on Nine in 2014.
Adrian Swift, Nine Network's director of development, said: "Our coaches are artists with busy careers and the time commitment to do back-to-back seasons is extensive, so we are thrilled we are able to work with Delta in having her be a part of 'The Voice Kids,' while simultaneously supporting her with her music goals."
'The Voice' Producer Talpa Bolsters Int'l Team With Executive Appointments
The new coaching line up for "The Voice Australia" also means that sisters Kylie and Dannii Minogue will likely front competing talent shows in 2014 if Dannii rejoins "X Factor Australia." Dannii, a former "X Factor U.K." judge jumped ship from "Australia's Got Talent," when it moved to the Nine Network this year to "X Factor Australia" where she coached this year's winner, Dami Im. Sister Kylie was a mentor for Dannii on the show.
"The Voice Australia" was just pipped by "X Factor Australia" as the number one talent show in the country this year with the "X Factor Australia" finale airing to 2.431 million viewers across Australia's five capital cities while "The Voice Australia" was a close second with 2.305 million viewers.
Being a judge on an Australian talent show has proven lucrative for international artists, if not creating a dizzying revolving door as they move between shows and countries.
Urban, a first time judge on "The Voice Australia" left after one season to take up on "American Idol." Former Spice Girl Melanie Brown (Mel B), was a long time judge on "X Factor Australia," but the Nine Network poached her to join "Australia's Got Talent" this year. However Seven was successful with an injunction to stop her moving to its competitor, leaving for free to join "America's Got Talent." Her place on the AGT judging panel was taken by fellow Spice Girl, Geri Halliwell.
Harrison Craig Wins Second Series of Australia's 'The Voice'
Minogue, Ronan Keating and local star Natalie Bassingthwaite at X Factor were joined this year by LMFAO's Redfoo. Meanwhile, "The Voice's" Madden won a top Australian TV award -- a Lioge award -- for best new TV talent this year.
In addition, Paula Abdul will also grace Australian TV screens – this time as a judge on "So You Think You Can Dance Australia," airing on network Ten in 2014.


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- Please select a date to see the proper prices!
Description of the accommodation:
Rooms, services The guests of Comfort Inn & Suites Brattleboro may stay in 56 nicely furnished, comfortable rooms in Brattleboro. The hotel is offering you freshly prepared fine local meals in its restaurant every day. Refreshing wellness services will be available on the spot, you may also use an indoor pool. Should you want to stay in good shape during your holiday, you may also take the sports and exercise opportunities provided by the local gym. The hotel is offering wireless Internet connection (WiFi) without charging extra fees, so you may go online anytime with your laptop during your stay. The exact scope of services offered by Comfort Inn & Suites Brattleboro (including those for an extra fee) is available on the information sheet below.
Payment In order to finalize the reservation you may be required to provide credit card guarantee or advance payment by credit card, depending on the chosen room, date and price.
Arrival, opening hours The earliest arrival time is 15:00, the latest time to leave the rooms is 11:00. The personnel speaks English.
Comfort Inn & Suites Brattleboro rooms Rooms
- Please select a date to see the proper prices!
Accommodation services
Free WiFi in shared places
- Indoor pool
Own restaurant
Hairdryer, Desk in the room, Tea/coffee-maker


text: NRL statement on Tim Simona Fri 17 Feb, 2017, 1:56pm Media Release, NRL Tweet Email Print Wests Tigers centre Tim Simona. Credit: Robb Cox. Copyright: NRL Photos. The NRL today issued a notice of intention to cancel the registration of Wests Tigers player Tim Simona.The notice relates to alleged breaches of the rules relating to gambling on NRL matches.Simona will now be prohibited from training or playing with the club until the matter is finalised.He will be given a chance to respond to the allegations before a final determination is made.The NRL will not be commenting further until the matter is resolved. Tweet Email Print Send to a friend: Your Name: Your Email: Friend's Name: Friend's Email: Close Submit loading image needs to go here


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The Glacier Bay WaterSense Aragon Single-Handle Tub and Shower Faucet in Chrome is practical and attractive and will complement a wide variety of bathroom decor. WaterSense certified, this faucet has a 2.0 GPM rate to help reduce water use and a washerless valve for smooth operation and long life. The single-handle design gives you convenient, one-handed control over water flow and temperature. Durable with an easy to clean chrome finish and acrylic knobs, this faucet is built to maintain constant water pressure for a comfortable shower experience. Pair with other pieces from the Aragon Collection for a complete and polished look. Limited Lifetime Warranty.
- WaterSense certified
- Solid brass valve body
- Integral stops provide easy maintenance
- Includes a plug for shower only installation
- Pressure balanced valve provides consistent water pressure
- Diverter tub spout included
- Advanced installation required - consult a plumber or professional before installing this product


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About: Cossham Hospital Cossham Hospital Bristol BS15 1LF
Posted via NHS Choices
I had a bladder ultrasound and was told the bladder and kidneys looked normal, yet when I read the report for this scan I was stunned to realise that my bladder was thin and there was urine left in my bladder post void. How does that equal a normal result please?
Do you have a similar story to tell? Tell your story & make a difference ››


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81010 is the Remind short code we created so people can join your class without seeing your personal information.
This is the class code for North families can always use fkb2c to join this class.
North Elementary 2016/2017
We LOVE Volunteers!
There are many ways you can help our school succeed! Holiday parties, book fair volunteer, grandparents' day helper, end of year activities are just a few ways our school needs you! If interested, please fill out the information below and return to school with your child.


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This paper presents a framework for development of a transformational change management program (Flamholtz and Randle, 2008) in an information technology (IT) organization of a global Fortune 200 consumer products company. The goal of the transformation was to build leading edge global IT service offerings, to internal and ultimately external customers. The program played a pivotal role in the company's "Path to Growth" Strategy. This strategy included very specific targets for sales, margins and earnings growth over a five-year period. The case illustrates how a well conceived change program, integrated with an organization's overall strategic plan, is a competitive advantage.
Published: Tarasovich, Barbara Magi and Bridget Lyons. "Choice Of Service, Choice Of Cost" - A Transformational Change Program In IT -- The Case Of A Global Consumer Products Company: Case Study." International Journal Of Business & Social Science 2.15 (2011): 39-52.


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Won-Han Cheng is a partner in the international law firm of K&L Gates, resident in its Seattle office, where she is a member of the Tax and Corporate practices. Ms. Cheng focuses her practice on the federal, state and international tax issues for both foreign and domestic clients including public and private corporations, partnerships and limited liability companies. She advises clients on partnership and corporate tax issues, restructurings and reorganizations, mergers and acquisitions and other tax planning issues. Ms. Cheng works extensively in the area of alternative investments, assisting institutional investors with investments in pooled investment funds including energy funds, private equity funds, hedge funds, venture capital funds and special situation funds.
Her experience includes alternative energy transactions including negotiating tax equity financing structures for the construction of wind and solar energy assets. Ms. Cheng is a co-author of the chapter, "Innovation in Tax Credit Structuring for Solar Energy Projects," in the publication Energy and Environmental Project Finance Law and Taxation (2010).
Ms. Cheng also works with clients on Washington state tax matters including audits, administrative appeals and tax planning.
Prior to joining K&L Gates, Ms. Cheng worked at "Big 4" accounting firms in Beijing. P.R.C. and Seattle, Washington.


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Way back on the Game Boy, around 20 years ago, Nintendo took another chance with their leading star (back then it was normal). Nonogram's, aka Hanjie Picross and Griddlers, are logic puzzles that create a simple image (recent variations have brought this type of game into the 3rd dimension). Mario's Picross is probably the most […]
Posts Tagged 'PixlBit Studios'
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Classic Nonogram Game PixlCross Reminds us of Mario's Picross on Wii U and Computers
August 27th, 2015 Carl Williams
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text:
- Please select a date to see the proper prices!
Description of the accommodation:
Rooms, services Are you about to reserve a room in China? We are glad to introduce you the offers of <Szálláshely neve/Property type>, where both you and your family will be very welcome for a stay. 112 comfortably furnished rooms are offered by the hotel to guests looking for accommodation in Beijing. In case you like doing exercises while you are on a trip, you should definitely try the gym as well. You can also bring your laptop for the holiday, for there is wireless Internet connection (WiFi) available at the hotel. The exact scope of services offered by Yong Ding Men Hotel - Beijing (including those for an extra fee) is available on the information sheet below.
Payment Credit card guarantee or advance bank card payment may be necessary for finalizing your reservation, depending on the exact room, date and price.
Arrival, opening hours The personnel can communicate with you in the following languages: Chinese - China and English.
Yong Ding Men Hotel - Beijing rooms Rooms
- Please select a date to see the proper prices!
Accommodation services
Free WiFi in shared places
Fridge, Desk in the room


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Written on: 29/03/2005 by Deirdre1977 (1 review written)
I bought a winter coat in Miss Sixty and I'll never buy anything there again. It cost £200 odd quid, which I justified to myself by saying that it would last at least 2 years.
Well three weeks later it had worn so badly that I was too embarrassed to wear it anywhere. It was a heavy 'wool' coat, clearly made of such bad fabric that it 'balled' really badly on me. Threads had pulled out and there the whole thing had fluffed up. It was horrible..
As rated by our community of reviewers
" Never order online " Read More
" What we wanted " Read More
" Wrangler Jeans " Read More
Written by Lestat70
" STONES FALL OFF " Read More
Written by clyne63
" Basic jeans " Read More


text: I don't know how to make a poll. Could someone who does generate a poll for which program , FB, MBB, WBB, Wrestling, fans believe will generate the most fan excitement next year? Looks to me like one or more of them has the potential for a really exciting year.