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Propeller JOHN McKAY. Of 8 tons. Built at Buffalo in 1868 by Gibson. Rebuilt in 1881. Owned by John Flynn, et al. Home port, Duluth. Value $2,500. Class A 2. REMARKS. -- Tug. Formerly AGATE.
Inland Lloyds Vessel Register, 1884
Steam screw AGATE. Official U.S. No. 1713. Of 7 gross tons. Built at Buffalo, N.Y., in 1868. Home port, Marquette, Mich. DISPOSITION:-- Abandoned 1883.
Merchant Steam Vessels of the United States
Lytle - Holdcamper list. 1790 to 1868
Steam screw AGATE. Official U.S. No. 1713. Of 7.68 gross tons. Built at Buffalo, N.Y., in 1868. Home port, Marquette, Mich. 39.5 x 10.6 x 4.8 Of 30 Nominal horsepower.
Merchant Vessels List, U.S., 1885
Steam screw AGATE.* U. S. No. 1713. Of 7 gross tons. Built Buffalo, N.Y., 1868. 39,5 x 10.6 x 4.8
* Renamed JOHN McKAY - U. S. - 1884
JOHN H. JEFFERY Jr. - U. S. - 1892 Redocumented as U 77021 ?
Herman Runge List
The Maritime History of the Great Lakes site is managed by Walter Lewis
Since 2005 this site has been the prototype for the digital collection management tools built for the Our Digital World (formerly the OurOntario project of Knowledge Ontario.)
As a prototype it is subject to occasional, unexplained interruptions in service ... because we keep trying new things.
My favourites lets you save items you like, tag them and group them into collections for your own personal use. Viewing "My favourites" will open in a new tab.
Login here or start a My favourites account.


text: On Fri, Oct 22, 2010 at 12:24:46PM +0200, Roel Schroeven wrote: > lee wrote: > > On Thu, Oct 21, 2010 at 11:39:22PM +0200, Andreas Weber wrote: > >> On 2010-10-21 22:48, lee wrote: > >>> On a side note: Someone once asked me why the text is moving up when > >>> you move the scrollbar down. Where´s the logic in that? Why isn´t the > >>> text moving up together with the scroll bar? > >> Seriously? It indicates the position in the document, and so it behaves. > > > > Yes, seriously, and I do see the point. You move the text with the > > scrollbar, so why does the text move into the opposite direction of > > the scrollbar? > > Because it doesn't move the text, it moves the viewing window in the text. The window isn´t moving, it remains at the same place on the display. When you move the window, the contents move with it. When you move the scrollbar, the contents of the window move. So you can´t argue that movement is relative.

subset: commoncrawl


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Caring, Comfort, Compassion
Cleveland Clinic Hospice prepares patients and families for the expected and the unexpected during the patient's last stage of life. Our professional, well-trained staff and volunteers provide compassionate care with an emphasis on symptom management and quality of life. By easing a family's responsibilities and providing comprehensive care for a seriously ill patient, hospice care can be a source of great comfort during a difficult time
You can call us for more information at 216.444.9819 or 800.263.0403, continue on this page, or visit our home page.
What is hospice care?
Hospice takes a team approach in treating patients at home or in a home-like setting. It promotes a strong bond between the patient, their loved ones and the health care providers, while addressing physical, psychosocial, emotional and spiritual needs. The goal of hospice is simple: to allow the patient to live until they die, without the fear of dying in pain, dying alone or losing control.
What is the mission of hospice?
Hospice care does not attempt to offer a cure for illness. Rather, it provides support to patients and families as they progress through one of life's most profound passages. The hospice care team, led by a nurse case manager, develops a plan best suited for the individual needs of each patient. In doing so, hospice care may include:
- Management of care by a team of experienced professionals
- Expertise in symptom management and pain control
- Providing medical care to include medications, medical supplies and equipment
- Teaching and support of caregiver regarding all aspects of care
- Volunteer supportive visits to patients and families
- Bereavement support
Hospice does not seek to prolong the life expectancy of a patient, nor to shorten it. The emphasis of hospice care is on providing comfort, not a cure; on the family, not just the patient; and on the quality of life, not its duration.
Most people choose to receive hospice care in their homes. However, if that is not possible, we can provide this care in many settings. Call us to find out more at 216.444.9819.
Who is eligible for hospice?
Cleveland Clinic Hospice serves people who live in the greater Cleveland area and surrounding counties, with networks throughout Ohio. Care is available to anyone regardless of age, diagnosis or reimbursement source who:
- Has a terminal illness with a life expectancy of six months or less
- Is no longer undergoing curative treatment
- Has identified caregivers available (family, friends, group home or nursing facility) or, if able to provide self-care at the time of referral, arranges for future needs
- Accepts the principles of hospice care
- Has a primary physician who agrees with the hospice philosophy
Who provides care?
Our hospice team is comprised of a variety of talented professionals who offer their individual skills in caring for the total needs of the patient. The team typically includes the following professionals:
- Medical director: a board certified physician who provides medical services and oversees patient care
- Nurse case manager: coordinates all care and is an expert in helping control pain and symptoms
- Social worker: helps provide important emotional support, assistance with finances and coordination of available community services
- Spiritual care: helps meet spiritual needs of patient
- Home health aide: provides personal care for the patient
- Hospice volunteer: a friend who offers a helpful hand
Range of services
- Access to 24-hour, on-call services every day
- Symptom management visits by physicians
- An effective medical model with extensive physician involvement
- Early intervention for pre-hospice, palliative and home care services
- Expressive therapies including music and art therapy
- Community-based volunteers
- Counseling services for emotional and spiritual support
- Bereavement support
Does insurance cover hospice care?
Coverage is provided by Medicare nationwide, Medicaid in most states, and by other private insurance providers. Insurance coverage assistance is provided for the patient's convenience.
Credentials, recognition and achievements
- JCAHO Accredited
- Medicare/Medicaid certified and licensed
- Ohio Hospice Organization
- National Hospice Organization
- Ohio Cancer Pain Initiative
Call Cleveland Clinic Hospice for more information at 216.444.9819 or 800.263.0403.
- National Institute on Aging. End of Life: Helping With Comfort and Care Accessed 2/5/2014.
- American Cancer Society. Hospice Care Accessed 2/5/2014.
- Hospice and Palliative Nurses Association. Patient/Family Teaching Sheets: Palliative Care and Hospice Accessed 2/5/2014.
© Copyright 1995-2014 The Cleveland Clinic Foundation. All rights reserved.
This information is provided by the Cleveland Clinic and is not intended to replace the medical advice of your doctor or health care provider. Please consult your health care provider for advice about a specific medical condition. This document was last reviewed on: 2/7/2014...#8818


text:
I'd go find it. =p
have a cup (or a whole cane if necessary) of lavender tee! it works.
otherwise, read some books
try to watch some bored DVDs... make ur room in dark... turn off the sounds.. watch but dont concentrate...may be helpful
Do some cleaning, too tired to lost sleeping, haha!
drink some hot milk, make you clam
Read and Smoke
睡不着的时候就上网 上社区中国网 www.chinasq.com
听着音乐 玩连连看
acount the sheep from a to z
听音乐 听着听着就Zzzzzzzzzzzzzz
get up and play computer


text:
Download the After Effects template for free!
Here is a fun After Effects template for a modern title technique called 'Call-Out' titles. I've been seeing a lot of titles in a similar style and this one is. This one is based off of a premium template you can purchase from VideHive here.
But as many of you know – I like creating my own motion graphics. So I took one of the samples and created this tutorial.
In the tutorial, the skills you'll learn include:
creating shape layers
animating shape size and position
adding and animating trim paths
adding and editing text
adding a typewrite text effect and customizing it to go backwards
attaching a path point to the background video / photo
I hope you enjoy this tutorial! If you have any questions regarding this tutorial, let me know! And if you have any more tutorials you want me to create, please comment below!


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Chicago Vintage Clothing and Jewelry show is brought to you by Vintage Promotions, LLC.
I started it five years ago, me, Melissa Sands. In 1999 I found myself wanting to do all things vintage. Buying, keeping and sometimes selling interesting objects. From any era, any category. Acquire it and learn. What would pull me in would be something strange or a vision of a different time. A time where they set a big table on Sunday's with the sterling and fine china. They dressed in their finest. It was the little details that would draw me in.
I've been hosting Vintage Garage Chicago, for 5 years now, and the Dallas Vintage Clothing and Jewelry show prior to that, along with other various pop-up vintage markets.
I've worked my way through many categories of collecting-- My favorite will always be vintage jewelry.
My dream show is a world class vintage clothing and jewelry show, right here in Chicago.
The Chicago Vintage Clothing and Jewelry Show will take place March 2, 3pm to 8pm, March 3, 2018. 10am to 5pm at 5649 N. Sheridan Road, Chicago, IL 60660. St. Andrews Greek Orthodox Church at the corner of Hollywood and N. Sheridan Road. The official website is www.vintageclothingandjewelry.com
Chicago Vintage Clothing and Jewelry Show, 5649 N. Sheridan Rd., Chicago, Illinois 60640, United States (US) - Phone: 312-505-6373 Email: email@example.com URL: http://www.vintageclothingandjewelry.com/


text:
|Home > Zilvia
♀ Zilvia
What does Zilvia mean?
Zilvia as a name for girls is of Latin derivation, and Zilvia means "woods, forest". Zilvia is an alternate form of Sylvia (Latin).
VARIANTS Zylvia, Sylvie, Sylvee, Sylva, Silvie, Silvia, Silva
RELATIONS VIA SYLVIA Silvana, Silvania, Silviana, Sylvina, SylwiaCREATIVE FORMS
Zilvia Grace (Z.G.), ..
How popular is Zilvia?
Zilvia is an uncommonly occurring first name for women. Zilvia is also an unusual surname for both adults and children. (2000 U.S. DEMOGRAPHICS)
Which version is better?
Prominent related forms of Zilvia (OUTSIDE TOP 2000) are Sylvia (#484 IN RECENT RANKINGS), Sylvie (#1183), Silvia (#1392) and Sylva. These relations of Zilvia were favored as baby names 105 years ago (ADOPTION OF 0.27%) and are now significantly less conventional (ADOPTION 0.05%, ▼83%), with the form Sylvia becoming somewhat outmoded. (TOP 2000 NAMES, 2015)
Similar Names
Zilvia is pronounced similarly to Sallvia, Salvia, Silvi, Silvy and Silvya. Other suggested similar-sounding names are Belvia, Cilia, Elvia, Filia, Fulvia, Gilia, Lilia▲, Lillia, Livia▲, Silia, Sillia, Silvija, Silvina, Vivia, Zalia, Zelia, Zila, Zilla, Zillpha, Zilpah, Zilpha, Zinia, Zinnia, Ziva, Zivka, Zolia, Zylia and Zylpha. These names tend to be more frequently used than Zilvia.See names in meaning and etymology.


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Friday April 21st, 2017
Doty Education Center - Intermountain Medical Center Campus
5121 Cottonwood St, Murray, UT 84107
HealthInsight is hosting a collaborative community event to promote end of life care awareness and the importance of communicating. Patients, families, researchers, providers, policymakers, payers and the local community are invited to this event to participate in interactive presentations and discussions. We will address end of life care issues in Utah and encourage community member input on planning conversations, addressing communication barriers, and fostering alliances between patients and providers.
Learning Objectives: At the end of this conference, participants will:
- Understand why advance care planning is important to you
- Know how to share advance care planning decisions with your family and health care providers
- Be able to effectively address advance care planning communication barriers within your family
- Be able to find the appropriate tools, resources, and contacts for you and your family's advance care planning needs
Read about the highlights and feedback from last year's End of Life summit in the event report.
This event was co-designed with partners from the Utah Department of Health, Intermountain Healthcare, the Utah Commission on Aging, Utah Health Information Network, Huntsman Cancer Institute, Regence BlueCross BlueShield, the University of Utah, and the Cambia Health Foundation.


text:
Christian Collins Wiki,Biography Height Weight Age Family Parents Details
Christian Collins is an Candian actor, musician and social media star better known for his youtube channell WeeklyChris. He has more than 2 million subscribers on YouTube where he post covers videos. His parents name are Stacey Collins and John Collins . He was born on April 18, 1996 and raised with three siblings namely Kirsten Collins, Crawford Collins, and Karisma Collins in Canada. On instagram he has more than 3.2 M followers. He release his official song You Don't Have To Go on youtube in 2016.
|Occupation : Youtuber, Singer
Age : 20 years old
Birthplace : Canada
Height : 5 feet 7 inches
Weight : 58 kg approx
Parents : Stacey and John
Girlfriend : Unknown
Nationality : Canadian
Twitter : https://twitter.com/WeeklyChris
Instagram : https://www.instagram.com/weeklychris/?hl=en


text: I needed an app to help me shut down items that would end up draining my battery or slow down other task I wanted to perform. I would run apps not realizing that they were running in the background after I pt the device away till I needed it again. I tried other apps but wasn't happy with them. I like the UI. Advanced Task Killer is the cream of the crop. This creative app allows you to easily see what applications are currently running and offers the ability to stop them fast and easy, thus freeing up valuable memory for other task and saving on battery life.


text:
A Western-type diet is associated with osteoporosis and calcium nephrolithiasis. On the basis of observations that calcium retention and inhibition of bone resorption result from alkali administration, it is assumed that the acid load inherent in this diet is responsible for increased bone resorption and calcium loss from bone. However, it is not known whether the dietary acid load acts directly or indirectly (i.e., via endocrine changes) on bone metabolism. It is also unclear whether alkali administration affects bone resorption/calcium balance directly or whether alkali-induced calcium retention is dependent on the cation (i.e., potassium) supplied with administered base. The effects of neutralization of dietary acid load (equimolar amounts of NaHCO3 and KHCO3 substituted for NaCl and KCl) in nine healthy subjects (6 men, 3 women) under metabolic balance conditions on calcium balance, bone markers, and endocrine systems relevant to bone [glucocorticoid secretion, IGF-1, parathyroid hormone (PTH)/1,25(OH)2 vitamin D and thyroid hormones] were studied. Neutralization for 7 days induced a significant cumulative calcium retention (10.7 ± 0.4 mmol) and significantly reduced the urinary excretion of deoxypyridinoline, pyridinoline, andn-telopeptide. Mean daily plasma cortisol decreased from 264 ± 45 to 232 ± 43 nmol/l (P = 0.032), and urinary excretion of tetrahydrocortisol (THF) decreased from 2,410 ± 210 to 2,098 ± 190 μg/24 h (P = 0.027). No significant effect was found on free IGF-1, PTH/1,25(OH)2 vitamin D, or thyroid hormones. An acidogenic Western diet results in mild metabolic acidosis in association with a state of cortisol excess, altered divalent ion metabolism, and increased bone resorptive indices. Acidosis-induced increases in cortisol secretion and plasma concentration may play a role in mild acidosis-induced alterations in bone metabolism and possibly in osteoporosis associated with an acidogenic Western diet.
- glucocorticoid
- acid-base
- potassium
- acidosis
- osteoporosis
chronic metabolic acidosis (CMA) is a frequent acid-base disturbance generated by extrarenal loss of base (e.g, diarrhea), increased acid production (e.g., organic acidosis such as ketoacidosis), or impaired renal acid excretion (i.e., renal failure and inherited or acquired forms of renal tubular acidosis).
CMA has a well-established potential for a catabolic effect on bone. In addition to renal phosphate wasting (28, 35, 36), experimentally induced CMA also results in hypercalciuria and negative calcium balance, attributable to calcium efflux from bone (10,34). CMA is associated with a poorly characterized metabolic bone disease (23), growth retardation (40), and calcium nephrolithiasis (7). In animal models, CMA results in a decrease in bone calcium and gravimetrically determined bone mass (2), decreased wet tissue femur density (41), accelerated rates of cortical and trabecular bone resorption (2, 20, 29, 41), and diminished rates of bone formation (24), resulting in reduced trabecular bone volume (29, 41).
In vitro studies have demonstrated that metabolic acidosis (imitated by the use of media with low ambient pH and bicarbonate concentrations) is a potent stimulator of bone resorption and inhibitor of bone formation (11, 32), suggesting that CMA acts directly at the tissue level to affect bone metabolism. However, CMA also might affect bone metabolism indirectly, i.e., via numerous well-characterized alterations in endocrine function that include parathyroid, thyroid, adrenal and growth hormone (GH)/IGF-1 dysfunction.
CMA decreases free serum IGF-1 levels during CMA in rats and humans (8, 15) due to GH insensitivity (8), results in a mild form of hypothyroidism (9), and increases the serum 1,25(OH)2 vitamin D [1,25(OH)2D] concentration (due to renal phosphate wasting) in humans, resulting in a decreased serum parathyroid hormone (PTH) concentration (28).
In addition, a hyperglucocorticoid response to CMA has been demonstrated in humans (39) and rats (48). The hyperglucocorticoid response has generated substantial interest because it might explain the negative nitrogen balance of CMA reported in normal rats (39) and humans (1). Support for this possibility is that the catabolic muscle proteolytic effect of CMA demonstrable in vitro in muscle from normal rats was not found in muscle from adrenalectomized rats with CMA (39).
The modern Western-type diet in humans, which is rich in animal protein, has been implicated as a cause of lifelong mild CMA with secondary bone catabolism caused by the induction by this diet of an obligatory daily acid load (endogenous acid production), due largely to endogenous oxidation of cationic and sulfur-containing amino acids (46, 53). Although still within the broad range of normal values, plasma bicarbonate concentration decreases progressively when endogenous acid production is increased by menu changes among normal foodstuffs in normal subjects (33). In support of the hypothesis that ongoing metabolism of the Western diet can result in net bone catabolism, it was demonstrated that prolonged neutralization of endogenous acid production in postmenopausal women resulted in calcium and phosphate retention, reduced markers of bone resorption, and an increase in serum osteocalcin concentration, a marker of bone formation (46). Several uncontrolled observational studies have provided evidence that loss of bone mineral density (BMD) in elderly humans is less while they are ingesting a presumed alkali-rich diet with higher levels of estimated fruit and vegetable intake (42, 47, 51). These observational studies are intriguing but not compelling, however, both because acid excretion was not measured and because the Framingham database examined over the identical time interval that suggested both static and dynamic BMD protection with high fruit/vegetable intake (51) also provided seemingly contrary evidence that high animal protein (but not nonanimal protein) intake is protective for BMD loss, even after correction for multiple covariates (25).
In addition, there is considerable debate on the issue of whether an increase in potassium intake (typical of a vegetable-/fruit-rich diet) rather than the alkali per se is responsible for the salutary effects on bone. Indeed, studies that administered NaHCO3 and sodium citrate have found little effect on urinary calcium excretion (34, 38, 45), whereas those in which KHCO3 or potassium citrate were administered have found large, significant reductions (34, 45, 46).
The present study was designed to assess the possibility that even the mildest CMA of the magnitude reported with the Western diet might be sufficient to cause significant abnormalities in at least one of the reported bone-active endocrinopathies of CMA described above. Hyperglucorticoidism of very small magnitude was viewed as a particularly likely candidate as an effector for diet-induced bone catabolism because a recent retrospective cohort study found that even very low glucocorticoid doses within the physiological range (i.e., <2.5 mg oral prednisolone daily) significantly increased both vertebral and nonvertebral fracture risk relative to age- and gender-matched controls (52).
The protocol was designed to measure the renal and systemic electrolyte, acid-base, and endocrine response to neutralization of endogenous acid production by oral ingestion of HCO in nine normal subjects. Nine nonsmoking subjects [6 men, 3 women, 22.1 ± 1.4 (SD) yr; body wt 70.6 ± 6.8 kg], who were taking no concurrent medication, ate a constant whole-food metabolic diet during all three consecutive study periods (control, neutralization of endogenous acid production, recovery). The diet was administered under metabolic ward conditions and provided the following total content per kilogram of body weight per day, inclusive of the electrolyte supplements described below: 1.42 mmol Na (32.7 mg), 1.18 mmol K, 0.412 mmol Ca, 0.58 mmol PO4, 16.1 mmol N, 0.24 mmol methionine, 36 kcal, and 47 ml H2O.
All subjects ingested 1.10 mmol chloride salt supplement/kg body wt−1 · day−1 during the control (9 days) and the recovery periods (5 days). The daily chloride supplement provided was equimolar (0.55 mmol/kg NaCl, 0.55 mmol/kg KCl). To experimentally neutralize endogenous acid production, a 7-day neutralization period followed the control period wherein equimolar NaHCO3 was substituted for the NaCl supplement and equimolar KHCO3 was substituted for KCl. All salts were administered in gelatin capsules in six divided doses daily.
Fasting arterialized venous blood samples (22) were obtained in a heparin-coated syringe from a heated hand or forearm vein. Blood samples were accepted only when Po 2was >70 Torr (9.3 kPa) and were obtained at 8 AM unless otherwise specified.
All volunteers were paid for their participation and gave informed consent. The study protocol was approved by the ethics committee of the Kantonsspital, St. Gallen, Switzerland.
Analytic procedures.
All measurements were performed in duplicate. Acid-base parameters in blood and urine were determined as described elsewhere (27). Analysis of hormones and their metabolites was performed as described previously (8, 9, 28, 48). Biochemical bone markers were determined using ELISA assays for deoxypyridinoline and pyridinoline (21) andn-telopeptide of type I collagen (24).
All steady-state values represent the mean of the last 2 days of the corresponding study period. Results are reported as means ± SE. Statistical analysis was performed by ANOVA for repeated measurements. Slope and intercept testing for plasma cortisol on time was performed using the general linear model procedure for two-way ANOVA with treatment and subject effects (SAS Institute, Cary, NC).
All volunteers tolerated the protocol well. There were no significant differences in body weights (Table1) and blood pressure (not shown) during any of the three study periods.
Administration of HCO resulted in a small but significant increase in the plasma HCO concentration (Table 1) from 24.8 ± 0.3 to 25.6 ± 0.3 mmol/l (P < 0.005), whereas renal acid excretion (net acid excretion) decreased significantly from 83 ± 5 to 12 ± 3 mmol/24 h (Table 2, Fig.1, P < 0.001).
As shown in Fig. 1 and Table 2, urinary calcium excretion decreased immediately, reversibly, and significantly during HCO administration and remained decreased throughout the 7-day HCO period, resulting in significant cumulative calcium retention of 10.7 ± 0.4 mmol/7 days (P < 0.025). Urinary phosphate excretion also decreased significantly and reversibly, resulting in a cumulative phosphate retention of 29.9 ± 1.2 mmol/7 days (P< 0.025). However, in contrast to calcium excretion, phosphate excretion values were decreased only transiently and returned to values not different from control and recovery values by days 6 and7 of HCO administration (Fig. 1, Table2). Consistent with the unchanged cation intake during the protocol, the cumulative changes in sodium and potassium excretion averaged only +23 ± 17 and −18 ± 7 mmol, values that did not differ significantly from zero.
As shown in Table 2, the fractional renal excretion of calcium, computed from the filtered load of ionized calcium, also decreased significantly from 1.84 ± 0.09 (control) to 1.65 ± 0.08% during HCO administration and rose again to 1.92 ± 0.09% in the recovery period (P < 0.05). In contrast, urinary phosphate clearance was not different among the steady-state days of the three periods. Thus increased renal tubular reabsorption of calcium accounted, at least in part, for the observed HCO -induced urinary calcium retention.
Figure 2 illustrates that markers of bone resorption (i.e., the urinary excretion of deoxypyridinoline, pyridinoline, and n-telopeptide of type I collagen) decreased significantly during HCO administration. The observed reduction in the excretion rates of bone resorption markers and sustained calcium retention in young adult subjects thus greatly extend the previous observation in postmenopausal women that neutralization of endogenous acid production leads to inhibition of bone resorption and positive calcium balance (46).
As neutralization of endogenous acid production might inhibit bone resorption by direct local acidification (±paracrine/autocrine effectors) and/or indirectly via alterations in endocrine systems known to be modulated by exogenous acid loads, i.e., the GH/IGF-1 axis, 1,25(OH)2D and PTH, thyroid hormones, and glucocorticoid activity (see the beginning of this study), we assessed these endocrine systems during steady states, i.e., the last 2 days of each study period.
As shown in Table 3, there were no significant differences in the serum concentrations of free IgF-1, 1,25(OH)2D, and intact PTH among the three periods. Similarly, serum TSH, free T3, and free T4 concentrations were also not affected significantly by HCO administration. Dynamic testing of any of these endocrine systems was not attempted during this study.
Table 4 demonstrates the diurnal changes in plasma ACTH and plasma cortisol concentrations. No demonstrable effect of alkali was noted on plasma ACTH levels throughout the day. However, plasma cortisol concentration at 7 AM was reduced significantly during the HCO period compared with control (416 ± 23 vs. 483 ± 39 nmol/l, P = 0.046), and the difference remained significant over all four measured diurnal values in the 24-h cycle (232 ± 43 vs. 264 ± 45 nmol/l, P = 0.032). Plots of the nine pairs of linear regression lines for plasma cortisol on time demonstrated a pattern of parallel slopes for cortisol decay throughout the day, and this pattern is also apparent in the homogeneity of individual slope values (see Table 5). When tested by two-way ANOVA, the mean slope for cortisol decay did not differ significantly during the HCO and Cl− periods; however, the mean y-intercept cortisol value during the control/Cl− period significantly exceeded the corresponding mean value in the HCO period, providing for a shift in the elevation of plasma cortisol decay throughout the day (Table 5).
To further analyze the effect of neutralization of endogenous acid production on glucocorticoid activity/production, cortisol and cortisol metabolites were determined in 24-h urine collections. As shown in Table 6, HCO administration decreased urinary free cortisol excretion significantly. Because tetrahydrocortisol (THF), cortisol's metabolite, is neither secreted nor reabsorbed in the renal tubule, altered tubular handling that could occur in the case of cortisol cannot account for decreased THF excretion (19). Figure 3thus concentrates on the excretion values for THF. As illustrated, HCO administration decreased 24-h THF excretion from 2,410 ± 210 mg/24 h for control to 2,098 ± 190 mg/24 h during HCO administration (P < 0.05) and recovered to 2,290 ± 220 mg/24 h (P < 0.05 compared with HCO period, not significant vs. control period). There was no significant change in the THF+allo-THF/tetrahydrocortisone (THE) ratio during all study periods (Table 6).
These results furnish the first evidence that a very mild Western diet-induced CMA (a degree of acidosis that would not be recognized by applying diagnostic acid-base criteria found in textbooks) results in a state of increased cortisol secretion and plasma concentration and provides several novel findings in humans regarding the possible causality of the Western diet in the etiology of osteoporosis. The present results demonstrate that ingestion of neutralizing alkali per se, as exchanged for chloride in the absence of other experimental maneuvers (e.g., concomitant potassium supplement), can result in urinary calcium retention and suppression of biochemical markers of bone resorption. Finally, the present study demonstrates that neutralizing alkali administered to very youthful male and female adults during the bone-anabolizing interval before achievement of peak bone mass can reproduce the bone metabolic effects of alkali plus potassium reported in postmenopausal osteoporotic women (46).
This study establishes that the arithmetically trivial degree of Western diet-induced CMA is part of an endocrine-metabolic continuum that includes the well-established hyperglucocorticoidism of moderate-to-severe CMA (39, 44, 48, 54). When even very modest CMA, of the magnitude produced by a Western diet, can result in increased cortisol secretion and plasma concentration, the intriguing possibility arises that idiopathic osteoporosis and/or postmenopausal osteoporosis might be modulated, at least in part, by hypercortisolism. That mild hyperglucocorticoidism of long duration can lead to osteoporosis is supported by a recent retrospective cohort observation that even very low glucocorticoid doses (i.e., <2.5 mg oral prednisolone daily) significantly increased both vertebral and nonvertebral fracture risk relative to age- and gender-matched controls (52). Because the increased cortisol secretion and associated increase in plasma concentration demonstrated in the present study are probably of smaller magnitude than the net glucocorticoid effect achieved even by quite modest prednisone dosing, its contribution to long-term putative bone loss incurred by the Western diet would presumably require many years of adrenal hypersecretion. Importantly, the pathophysiology of glucocorticoid-induced osteoporosis in humans shares with postmenopausal osteoporosis the two fundamental features found in experimentally induced CMA, namely, decreased trabecular bone formation/osteoblast recruitment rate and a component of early accelerated resorption (14, 49).
The finding that the urinary ratio [THF+allo-THF]/THE is unchanged in the prolonged transition from/to hypercortisolism of diet-induced CMA suggests that 11β-hydroxysteroid dehydrogenase type 1 isoform (11β-HSD1) activity in liver and adipocytes and renal 11β-HSD2 activity are grossly normal. However, the skeletal activity of either or both HSD isozymes is not known to be reflected in the excretion rates of urinary metabolites. 11β-HSD1 is strongly expressed in normal human bone in both osteoblasts and osteoclasts, whereas 11β-HSD2 is weakly expressed and only in osteoblasts (16,18). The glucocorticoid receptor may only be expressed in osteoblasts (5). The finding that administration of carbenoxolone, a potent inhibitor of both 11β-HSD isozymes, to normal subjects resulted in a significant decrease in pyridinoline and deoxypyridinoline excretion (18) suggests that variation in the activity of these isozymes in osteoblasts or osteoclasts or both can result in important alterations in glucocorticoid receptor-mediated action on bone metabolism. The recent in vitro findings that 11β-HSD1 (cortisol-generating) activity in human osteoblasts is increased by increasing ambient cortisol concentrations and that its osteoblastic activity is increased as a function of a subject's age provide evidence that even very small increases in plasma cortisol concentrations in humans may be subject to autocrine amplification loops deleterious to skeletal function (17). Thus the effects of CMA on these isozymes in bone remains an important unanswered question.
The present results provide the first evidence in any species that the alkali (as exchanged for chloride) vs. acid content of a diet per se, rather than the specific effect of a coadministered alkali-associated cation (sodium or potassium), modulates bone resorption and the associated alterations in calcium and phosphate homeostasis. Whether alkali per se has a clear role has remained a question because studies in which NaHCO3 and sodium citrate were administered have found little effect on calcium excretion (34, 38, 45), whereas those administering KHCO3 or potassium citrate have found significant reductions of large magnitude (38, 45,46). The present study, by holding cation intake constant and exchanging equimolar HCO for chloride, has eliminated the argument that modest alkali treatment per se might be insufficient to cause urinary calcium retention in the absence of a concomitant increase in potassium intake. A specific role for the reduction in chloride intake in producing renal calcium and phosphate retention and decreased markers of bone resorption was not apparent in the present study, but it was not rigorously excluded.
Part of the confusion over the relative hypocalciuric roles of alkali and coadministered cation has arisen because of the interpretation of a study in adult male subjects ingesting a normal diet in which sequential 4-day periods of KCl and then KHCO3administration were undertaken (37). Both the authors of that study and others (12) have interpreted those data as indicating that KCl as well as KHCO3 administration to potassium-replete subjects resulted in decreased urinary calcium excretion, yet the reported data for the 4 days of KCl administration (unlike the KHCO3 results) showed no significant difference in calcium excretion relative to paired control values in the same subjects despite a similar magnitude of potassium retention with both potassium salts (37). Furthermore, in contrast to significant hypercalciuria produced by prolonged NaCl loading, no effect of prolonged KCl loading on calcium excretion was reported in healthy young women (3). On the basis of the in vivo literature to date, small alkali-independent effects of primary alterations in potassium balance on calcium retention would be difficult to detect in initially normokalemic animals or humans and have not been reported. However, by the use of a very low extracellular fluid potassium concentration of 1.0 mM, cultured murine calvariae exhibited an effect of low medium potassium concentration to increase calcium efflux, to increase a bone resorption marker, and to decrease bone collagen synthesis (12) in the absence of detectable acid-base change. The applicability of the in vitro data in calvariae to human potassium depletion is uncertain because the significant hypercalciuria reported in diet-induced potassium depletion in normal subjects was accompanied by renal NaCl retention and weight gain, suggesting a role for extracellular fluid volume expansion in the etiology of hypercalciuria (26). Thus whether the bone catabolism findings for a potassium-depleting environment in vitro predict an in vivo bone anabolic effect of potassium loading in potassium-replete humans awaits future studies.
The present studies do not exclude cortisol-independent mechanisms for mild CMA-induced reversible effects on bone metabolism. Local mechanisms in bone have been elucidated that might explain the effect of CMA in causing bone loss. In mature mouse osteoclasts in culture, acidified medium results in upregulation of both carbonic anhydrase II and calcitonin receptor, the former being associated with increased resorptive activity and the latter with suppressed osteoclastic activity (12). In cultured murine calvariae, acidification of the medium results in calcium efflux accompanied by enhanced PGE2 production (30), and calcium efflux is inhibited by both nonselective clyclooxygenase (COX) inhibitors and COX-2-selective agents (31). Cultured osteoclasts also exhibit important morphological and functional changes to acidified media that include formation of the resorbing clear zone podosomes (4) as well as augmentation of the final step in resorption, activity of the V-type plasma membrane H+-ATPase (43). Thus CMA-induced bone catabolism might conceivably be mediated within bone by a variety of plausible mechanisms. We also cannot exclude the possibility that alkali-induced increases in distal HCO delivery might have resulted in suppressed bone resorption as mediated by tubular calcium retention. We believe that this is an unlikely mechanism in the present study because we found no alkali-induced suppression of PTH levels nor ionized hypercalcemia, which are recognized as the mediators of the small suppressive effects of calcium loading on bone resorption markers reported in young adults (6).
We did not find evidence for an effect of neutralization of acidogenic diet on other endocrine axes [i.e., GH/IGF-1, PTH/1,25(OH)2D, and thyroid hormones], which are important to bone integrity and are affected by acidosis (Table 3). However, subtle regulatory alterations cannot be excluded, i.e., altered sensitivity of feedback loops and end-organ hormone (i.e., GH) sensitivities.
In summary, we have provided novel evidence that ingestion of an ordinary acidogenic Western diet to normal young adult subjects results in a mild CMA in association with a state of increased cortisol secretion and plasma concentration, altered divalent ion metabolism, and increased bone-resorptive indices. Because mild hyperglucocorticoidism is reported to result in an osteoporotic state that shares numerous qualitative and quantitative histomorphometric features with postmenopausal osteoporosis and with experimental CMA in animals, it is proposed that CMA-induced cortisol excess may play a role in mild CMA-induced alterations in bone metabolism in humans and possibly in osteoporosis associated with the Western acidogenic diet.
Address for reprint requests and other correspondence: R. Krapf, Medizinische Universitätsklinik, Kantonsspital Bruderholz, CH-4101 Bruderholz/Basel, Switzerland (E-mail:reto.krapf{at}ksbh.ch).
The costs of publication of this article were defrayed in part by the payment of page charges. The article must therefore be hereby marked "advertisement" in accordance with 18 U.S.C. Section 1734 solely to indicate this fact.
September 24, 2002;10.1152/ajprenal.00212.2002
- Copyright © 2003 the American Physiological Society


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The Golden Tulip Hotel sounds like a cozy and local Amsterdam inn, but it's actually the flagship of a Dutch chain of hotels with 900+ locations in 50 countries. This central Amsterdam location is one of 9 hotels in and around Amsterdam itself. This is a 4-star property with 239 rooms and a very convenient location for business travelers and families, but not necessarily for other tourists. It's not a typical cheap Amsterdam hotel and the prices reflect that. Everything is of international standard here, which sets it apart from many of the budget hotels in the city that have small rooms and lightweight furniture. All the rooms have free wifi, free coffee & tea service, a safe, a minibar, and everything else you'd expect to find in a luxurious business or resort hotel.
Location and neighborhood
Nieuwezijdskolk 19 ?
1012 PV, Amsterdam
The Golden Tulip Hotel – Amsterdam Centre is located on a fairly busy street very close to Centraal Station and Dam Square. The main shopping district is in the area just behind the hotel, and there are many restaurants and bars in this area as well, although it's not particularly close to the best nightlife areas, which are Rembrandtplein and Leidseplein. In fact, being close to the train station, many of the restaurants and bars in the area tend to either cater to business travelers or be overpriced places that draw in tourist foot traffic.
There is an expensive parking lot next door, and very good road access so the location is ideal for those with a car and an expense account. The public transportation in Amsterdam is excellent though, and many trams run right along this street so you can be nearly anywhere in 10 minutes or so. The main museums are in the Museumplein area, which is about 20 minutes away on foot, but much less by tram.
As is typical of a hotel targeted at business travelers and higher-end tourists, the Golden Tulip Inntel Amsterdam Centre has variable rates based on season and availability. If you book earlier you can often get a better rate than if you book at the last minute.
Standard rooms €105 to €205 per night, depending on season and availability
Executive rooms €131 to €220
Deluxe rooms €157 to €250
All prices exclude breakfast. Higher rates can apply for Queen's Day, Easter, New Years, and other special events and holidays.
Much more information and occasional specials can be found on the hotel's official website.


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THE election of a new president of Pakistan having been completed, efforts should now be concentrated on securing for the presidency the dignity that it is supposed to be guaranteed in responsible democracies.
Before discussing such efforts, one must regret the fact that Tuesday's presidential election became quite controversial. Hopefully the unwelcome episode will be forgotten before long.
Meanwhile, the government must be felicitated on foiling the Election Commission of Pakistan's plot to disrupt Prime Minister Nawaz Sharif's plans to be in Saudi Arabia on Aug 6. His visit to the holy places this year is especially significant. Thanksgiving prayers ought to be offered at the earliest. Also in future aitkaf in Saudi Arabia may not be easy for a fully functional prime minister as the exercise demands a break from all worldly concerns and a ban on speaking — something quite hard for a politician to manage.
Circumstances over the past five decades have almost continuously undermined the prestige of the presidency. Gen Iskander Mirza, the first president, earned fame for changing the country's prime ministers as casually as he changed his tuxedo. He also invited obloquy for proclaiming martial law and abrogating the constitution that had been enforced under his own signature.
Then we had presidents-general Ayub Khan, Yahya Khan, Ziaul Haq and Pervez Musharraf. As president, they were subservient to their rank as general. What Ayub, Yahya and Zia did in that capacity is history. Even Pervez Musharraf carried out a coup against his own regime on Nov 3, 2007 as general and not as president. The anti-democratic actions of the presidents-general considerably compromised the dignity of the presidency.
The last few years have been especially bad for the presidency's image. The persistent vilification of President Asif Ali Zardari by the media and other actors — whether justified or not is beside the point —– made the presidency a legitimate target for ridicule, invective and slander.
It is to be hoped that all parties while exercising their right to criticise the government will do so in a manner so that the institution of the presidency is not downgraded. There is much to be learnt from the Supreme Court's ruling against arresting a brigadier on the ground that the dignity of institutions should not be harmed.
The first thing that is needed to establish the presidency as an august symbol of the federation is to ensure that the president knows how to function within his constitutional limits. One hopes the president-elect does not share the ambition of retired justice Wajihuddin Ahmed who was reported to have said that if elected he would change the face of the country. He should have known that by himself the president cannot change even the façade of President House.
Mr Mamnoon Hussain has resigned from his party membership. His new office will demand much more than that — he will be required to completely forget his party affiliation, something easier said than done. For that reason democratic countries often choose as head of state eminent citizens instead of party loyalists.
India set a good example by electing educationists/scientist Dr Radhakrishnan, Dr Zakir Husain and Dr Abul Kalam although it also elected a president who was proud of polishing the prime minister's shoes. It is a pity Pakistani kingmakers have never thought of honouring persons outside their favourites or men whose favours had to be repaid.
In the days when presidents had sweeping powers there could be a reason for ruling parties to have their trusted man (women are still out of the reckoning) in the presidency. But now the president is a ceremonial head of state and it is possible to take the risk of choosing him from among some outstanding citizens who are respected by the people both for their accomplishments and uprightness.
Some thought should also be given to making the presidential addresses to parliament meaningful. These addresses are essentially statements of what governments wish to do during their terms of office or from year to year. The president merely reads out the government brief.
In Pakistan's polarised politics, presidential addresses have become occasions for a trial of strength between the ruling party and the opposition. The people are the losers because the objective of a rational debate on the government's vision/programme is lost. The need for a forward movement in this area is obvious.
As the symbol of the state the presidency is looked up to by citizens in distress as the final executive authority. Our people have a long tradition of seeking relief through the presidency's intervention.
They present their plaints to the president's public secretariat where a generally bored factotum marks the papers to X,Y,Z and X,Y,Z reply after long delays that the case has been taken note of and there the matter ends. This is shoddy eyewash. It should be possible to ensure timely and reasonable action on public complaints to the presidency.
The president represents the state's capacity for benevolence, for mercy. It is to serve that purpose that provisions similar to Article 45 of the Pakistan Constitution — providing for the president's power to pardon and commute sentences — are included in the basic laws of most countries.
This article has unnecessarily been rendered controversial since the Qisas and Diyat law was enforced. Nothing has happened to extinguish the president's powers under Article 45. In any case, the Qisas law does not affect the president's powers in cases in which murder is not the offence. A greater exercise of the president's power of clemency will endear the people to the state. The restrictions on the use of his authority under Article 45 must be substantially relaxed.
The non-partisan status of the president will appear in bold relief if he is seen overseeing an even-handed fulfillment of the state's benevolent functions that have progressively been consigned to oblivion.


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Laura's Thought of the Day -21 Oct'12
Posted on October 21, 2012 by multidimensionalocean
Have a super week everybody! Full of joy, love, energy, happiness, excitment and beautiful dreams! Have a peaceful loving evening, feel Mother Earth's love for all that is. Don't forget to be kind to yourself, to listen to that small … Continue reading →
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Luxury White Hot Chocolate
Whittards Luxury White Hot Chocolate captures the exquisite sweetness of white chocolate to the full. It is a deliciously smooth and decadent drink with a melt-in-the-mouth intensity that leaves you wanting for more. Deliciously creamy and as soft as velvet, its not hard to see why this is one of our best-selling hot chocolates.
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Finest Coffee Collection Gift Box
A connoisseur(TM)s collection of eight luxurious single origin ground coffees.Contains coffees with different strengths, from mild-medium (2) to strong (5). Coffees included are Mocha Djimmjah (mild), Costa Rican (mild), Pico Duarte (medium), Colombian (medium), Nicaraguan (medium/strong), Sumatra (strong), Monsoon Malabar (strong) & Old Brown Java (strong).Ground coffee, suitable for use in cafetieres and most coffee makers.Height: 34cmLength: 16cmDepth: 9.5cm
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Whittard(TM)s Banoffee Flavour Hot Chocolate is bursting with the flavour of banana and cream and is a must for anyone who loves banoffee pie.The flavoursome hot chocolate is inspired by the traditional dessert, made from bananas, cream, toffee and condensed milk on either a pastry or crumbled biscuit base. It is a truly indulgent experience perfect for offering warm and sweet comfort on any cold day, or whenever you need a treat.
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Chocolate by Cocoapod Chocolate Personalised Chocolates For Easter
Create your own personalised Easter message in solid blocks of delicious couverture chocolate. A lovely chocolate gift to surprise family or friends on Easter morning To add interest the colourful pattern blocks have various Easter patterns to choose from in a choice of milk or white chocolate Hand made by COCOAPOD in a choice of dark or milk Belgian couverture chocolate with white letters on the top of the chocolate Carefully packaged in a smart white box with chocolate brown sleeve which will slide to reveal your message perfectly. Cocoapod Chocolate Ingredients Dark Chocolate ingredients: cocoa mass, sugar, cocoa butter, emulsifier: SOYA lecithin; natural vanilla. Dark chocolate min. cocoa solids 53% Milk Chocolate ingredients: sugar, cocoa butter, whole MILK pow
Chocolate Football Boot
Inspired by the golden boot award which is traditionally given to the top goal scorer this Chocolate Football Boot is made from milk chocolate and features a delicious contrast of dark chocolate studs on the bottom of the boot. Fun tasty and a little bit different – this chocolate boot is sure to bring a smile to anyone's face no matter what the occasion. A delicious and thoughtful gift for the ultimate football fan and made from premium quality Belgium chocolate – this yummy gift is sure to please the ultimate chocolate fan too. Dimensions: Length: 20cm Width: 5.5cm Height: 7.5cm
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Results 1 to 3 of 3
02-04-05, 06:19 #1Registered User
- Join Date
- Feb 2005
- Posts
- 29
Unanswered: hi all need some help or import cmd
Hi i'm quite new to access and was figuring out how to program using the DoCmd.TransferSpreadsheet.
I have a code attached to a a button like below
DoCmd.TransferSpreadsheet acImport, 8, "Bony2", "C:\Documents and Settings\XXXX\Desktop\3.xls", True, "A1:K80"
the probelm is i want the user to specified the cell range to import. Maybe i can give a text box for user to enter that value but how to transfer that value back to the above code.
If i don't want the user to specify the range and leave it blank in the above code....access always prompt me that a field doesn't exist in my access database. However i had everything in tact and the required field and property done up. If i specified the range then everything is ok. So anybody can advice?
Thanks in a dvance for any help i could get.
02-04-05, 06:47 #2Registered User
- Join Date
- Feb 2005
- Location
- England.
- Posts
- 232
I'd suggest your best bet would be to put a text box onto a form where the button resides. Then I'd suggest your code to be ...
Private Sub cmdTranser_Click()
Dim strRange as string
strRange = txtRange.text
DoCmd.TransferSpreadsheet acImport, 8, "Bony2", "C:\Documents and Settings\XXXX\Desktop\3.xls", True, strRange
End Sub
Something like this should work, although the range the user specifies would have to have the ':' in there too.
Hope this works and hope it help.
02-07-05, 09:50 #3Registered User
- Join Date
- Feb 2005
- Posts
- 29
Hi daveo61 thank for your help. Haven't try yet but i think it will work...thanks alot


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London: Jesuits to hand parish back to archdiocese
Corpus Christi Parish, Brixton Hill, south London, is to be handed back to the Archdiocese of Southwark after 25 years of being in the care of the Jesuits. The British Provincial of the Society of Jesus (Jesuits) made the announcement at all Sunday Masses at Corpus Christi, having met with the Parish Council on the Saturday afternoon. Since 1980, the Jesuits have been serving the parish at the request of the then Archbishop of Southwark, Michael Bowen. The Jesuit Provincial, Fr David Smolira SJ, said that "Looking back over the last 25 years I can unequivocally state how proud the Jesuits are to have been associated with such an energetic and dynamic parish." Fr Smolira went on to point out its many strengths: " the rich mix of races and cultures who worship and socialise together; the real sense of welcome and the genuinely caring community that exists; the first rate sacramental programmes and the large number of other groups that flourish here; the superb level of collaboration that takes place between the priests and the lay people who play such an active and enthusiastic role in the parish; the wonderful primary school and its contribution to parish life; and so much more." The Jesuit Provincial was accompanied by Monsignor Richard Moth, the Vicar General of the Southwark Archdiocese. On behalf of the current Archbishop, Kevin McDonald, he expressed the deep appreciation for the work that the Jesuits had done in Corpus Christi over the past 25 years. Fr Smolira characterised the Jesuit vocation in terms of "mission", explaining that this meant being sent where the need is greatest, where the work is not being done by others and where God can best be served. The withdrawal from some of the Jesuits' more established works will enable the development of new initiatives to better serve the needs of the Church of today and tomorrow. Although the Jesuits will no longer be running the parish in Brixton Hill, they will still be present in the parish as they are retaining their two nearby houses of Formation (Jesuits in training). The date for the handover is expected to be in the late summer of 2005. Source: Jesuit Communications Office


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Philip Kolvin QC
Philip Kolvin QC is Head of Cornerstone Barristers. He is a licensing barrister, acting for national and local regulators, the licensed industry and community groups. He is a Patron and past Chair of the Institute of Licensing, the professional body for licensing practitioners; a board member of the Sports Grounds Safety Authority; a former Chair of Purple Flag, the national awards scheme for safe and diverse town centres; and a former Chair of Best Bar None, the national scheme for safe bars.
He is the author of a number of textbooks in his specialist field. As a local campaigner he is a member of the shadow Board for Crystal Palace Park and a former Chairman of the Crystal Palace Campaign. He led a campaign to extend the South East London Green Chain Walk from Outer to Inner London and helped save the Herne Hill Velodrome, a grassroots community facility, from redevelopment. He loves the theatre and lives in South London with his family.
Find out more about London's night-time economy.


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Manhattan federal prosecutors Wednesday charged seven New York-area Army National Guard officers with engaging in a recruitment kickback scheme.
Two salaried National Guard recruiters, Evette Merced and Darryl Harrison, allegedly passed information on potential recruits to soldiers who were eligible to collect bonuses of up to $2,000 for identifying recruiting prospects, and then split the take with them.
A criminal complaint filed in U.S. District Court in Manhattan indicated that information on at least 60 potential recruits may have been passed to soldiers who had signed up as so-called "recruiting assistants" to collect the bonus payments, and at least $62,000 was paid for the phony recruiting leads.
The complaint said that Harrison worked out of the Army Guard's Brooklyn and Queens recruiting offices, and Merced, his wife, worked out of the Army's Bronx recruiting office. As salaried recruiters, the complaint said, neither was eligible for any bonus payments.
Merced and Harrison, of East Stroudsberg, Pennsylvania, both are now sergeants. They were released on bail after a court appearance Wednesday afternoon.
The five soldiers named in the complaint are also now sergeants. One was identified as NYPD Officer Jefferson Simbanamuzo of the Bronx. Four were released on bail in New York, and one, Yesania Adames of the Bronx, was arrested in Virginia and detained after a bail hearing there.


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Finding Altamira 2016 1080p BluRay x264 DTS-HD MA 5.1-FGTSep 13
Altamira (original title)
Plot: Marcelino Sanz de Sautuola y de la Pedrueca, in 1868, accidentally discovered Patheolitic paintings with the help of a hunter named Modesto Cubillas inside Altamira's caves, located in Cantabria, north to Spain. Trying to expose their discovery to the academic world for that they study the paintings, Sautuola crashed against the skepticism and discredit of all experts, who claimed that the caves were false and the paintings made for the own Sautuola, in a effort to get rich. Looking for the truth, Sautuola was the rest of his life fighting to prove that those paintings were real, trying to restore his innocence from the accusations of falsehood launched against him.
Genre: Drama | History
IMDB Rating: 6.0/10 from 232 users
Directed by: Hugh Hudson
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Release Name: Finding.Altamira.2016.1080p.BluRay.x264.DTS-HD.MA.5.1-FGT
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I just love everything about Parker Street Ministries.I adore all the staff.I volunteer as much as I can.
Previous Stories
I love Parker Street Ministries' after-school tutoring program because it helps my kids with their homework. I really like the fall festival because I don't like to go trick or treating. That's a good idea. I love how I can come in and volunteer and have hands-on participation with my kids. They continue to learn skills on their next grade level during the summer. I volunteer in the kitchen where they serve a balanced hot meal. I'm disabled and would not be able to afford to send my kids to a program like this. I'm happy that it is free. This doesn't even scratch the surface on things that I love about Parker Street.
Parker Street has proven itself and continues to prove itself as an indispensable asset to the Parker Street neighborhood and Lakeland as a whole. My kids have been a part of this program for years and are better for it. Their staff not only does amazing at their jobs, but they are also involved residents of the neighborhood. That fact alone proves their commitment to the neighborhood and the residents.
I became involved with Parker Street Ministries approximately 3 years ago when we moved into the neighborhood. One of my neighbors, that I met soon after told me about a great organization that offered an afterschool program and summer camp, that also picked up and dropped off! I was truly intrigued by this point and immediately called the program director, Christina Allen and after filling out all paperwork my daughter, Nani was able to start the following week and the best part was I didn't have a fee if I devoted a few hours each month of volunteering. This was an absolute blessing! We have been involved with the program ever since. I recently began volunteering in the office as an assistant, and my daughter is continuing in the afterschool program which also offers homework assistance and the students can use the computers for other school assignments, which has been amazing. The entire staff at Parker Street Ministries is a blessing. Each and every time we have been in need they have come through for us no matter what the need was and have done so graciously! I really cannot say enough about how awesome Parker Street Ministries is they go above and beyond for the families in the neighborhood.
We need a ten star rating for Parker Street! I remember when I didn't have a job and I was down and depressed. I was able to come up to the office and hangout and they helped me get out of that. When my son had got into some trouble, they came over and set me down and talked to me and encouraged me not to give up on my son. I love how they encourage people not to be afraid, but to drop by the office when there's a need.
Parker Street Ministries has greatly and deeply enriched our lives. We have nine children who have all greatly benefited in one way or another from the ministry. Whether it is coming by on a difficult night to help with the children, or volunteering to babysit while my husband worked long hours and I attended college, or sitting bedside holding my hand while our youngest daughter came into the world, or bringing by a meal when our grocery budget just wasnt enough, Parker Street Ministries, as the physical embodiment of Christ's love for us, has continuously met the many needs of our family. The staff has spent countless hours praying for us and tutoring our children and pursuing relationships and deep lasting friendships with each of us. The best part to me though is the fact that God used the ministry to bring both my husband and myself to Jesus. There are truly not enough words for me to write to adequately express the deep appreciation and love I have for the ministry and to describe the deep impact they have made on our lives. Its truly unlike any other non profit I've ever been in contact with.


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74 Walnut Hill Rd, Chestnut Hill, Maranhao 02467, USA. Phone: +1 617 325 7796, Fax: +1 619 881 3010 Email: milesoftrials01[AT]yahoo.com


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The company lays claim to proprietary products for heat recovery and the conversion of waste heat to useful purpose. Forcefield comes by this capability though a 50.3% interest in TransPacific Energy based in the U.S. Forcefield is also a distributor of LED lighting from LightSky, a China-based LED manufacturer. Another China-based subsidiary is involved in the production of trichlorosilane, a chemical that is used in the production of polysilicon for photovoltaic cells. That subsidiary was sold in February 2014.
Forcefield management describes the company as "a new force in the field of energy." Certainly with all these energy-related interests it seems formidable, at least until an investor looks at the company's financial performance. With the chemicals business out the door, revenue has been shrunk down to just $295,250 in the most recently reported twelve months and the company lost a net $2.1 million. In the same period Forcefield burned up $3.8 million in cash to support operations.
FNRG shares are now trading at a multiple of 290 times sales - a valuation which is probably not sustainable. Forcefield management has a challenge before it. It is understandable, in the interests of building a 'clean, green' business model, why management would divest of a messy chemical operation. However, neither its waste-to-energy business nor the LED lighting sales are sufficient to make up for the chemicals revenue. New strategic relationships hold considerable promise, but none have delivered significant new revenue.
Forcefield Energy made an appearance at the Marcum Micro-cap Conference in New York two weeks ago. It is well that management is making an attempt to bring investors up to date on the strategic changes in the company's business model. Management was to win new shareholders, but it might be premature to take a position in stock sitting well above its sales value.
Neither the author of the Small Cap Strategist web log, Crystal Equity Research nor its affiliates have a beneficial interest in the companies mentioned herein. Forcefield Energy (FNRG) is included in the Waste-to-Energy Group in the


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Contact Info / Websites
All 2 game Reviews
League of Angels
Rated 5 / 5 stars
I love this game. It's addicting, and there is always new features getting added in as you level up your character. That means, more and more things to do without a slight bit of boredom. Especially the daily tasks/events always in multiple hours of the day is quite amazing. I really like the game, however I feel like VIP/diamond people get way too much power in playing this game. Other then that, I really like it! Keep the good work up!
Pokemon Tower Defense
Rated 5 / 5 stars
*sniff* This is a freakin awesome game! Oh btw is there anyway that you can include catching Mew and Mewtwo in that game? I just love Mew and Mewtwo! :3


text: I have been seeing alot of advertisement on rubber mulch. I was just wondering if this a high customer demand and if any one had luck with it. The one i seen in Total Landscape care is 30lb bag for $ 5.50 comes in 7 colors. Don't know if it would be worth trying?


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Update on February 01, 2013
- Update #2
Our Maya is here with us and slowly her front leg is healing too. Her bandage must be changed daily and because outside it is too cold for her, she's staying inside with Victoria and her dogs. From now on, that we've passed the big threshold, we hope to a…Read More


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Jennette Mccurdy can now say she has joined the likes of Miley Cyrus, Vanessa Hudgens and Dylan Sprouse. A unique group of Disney/Nickelodeon stars that have had some photos leak to the internet that really should not be there. Jennette Mccurdy in the past has starred along side Miranda Cosgrove on the hit Nickelodeon show ICarly. She is 21 now and still on Nickelodeon with a show called Sam & Cat starring along side Ariana Grande.
Good and bad things can come from these leaked photos in my opinion. Miley Cyrus for example has completely embraced her new image with things like her VMA performance and her extremely popular and somewhat backlashed Wrecking ball music video. Vanessa Hudgens had some seriously bad images leak a few years back and its pretty safe to say that she has done a complete 180 and had some very good performances in movies like Spring Breakers, The Frozen Ground and most recently Gimme Shelter. Photos like these can mean good and bad for actresses like Jennette Mccurdy, but in my opinion I think its time she get out of Nickelodeon and look for some mature rolls in Hollywood. It has worked for many actresses in the past so who's to say it wont work for her.
The photos that have leaked really are not that different from her walking on the beach with a bikini, but everyone knows the general public won't see it that way. I think that Jennette Mccurdy will get though this pretty easily. Its not as bad as people may think. She may be done at Nickelodeon after this and I'm pretty sure she will be. Nickelodeon will most likely not take her back as a result of these leaked photos, but Jennette Mccurdy now has a chance to really prove herself in some more mature rolls in Hollywood. Maybe this is her wakeup call to move on.


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- Please select a date to see the proper prices!
Description of the Accommodation
Rooms, services The guests of RADISSON BLU ABU DHABI YAS ISL Abu Dhabi may stay in a nicely furnished, comfortable room in Abu Dhabi. In case you'd like to have a meal or a drink on the spot, you will be provided freshly prepared dishes in the restaurant every day. Available wellness services will provide you the opportunity to refresh yourself. Car rental service and organized city tours are also available to help you discover all key highlights of the area. The café and the bar provide a nice atmosphere for a romantic evening talk or a personal meeting. An exact and detailed list of equipment in the rooms and of the services provided by RADISSON BLU ABU DHABI YAS ISL Abu Dhabi you will find on the information sheet below, including any applicable additional fees.
Payment Advance bank card payment or credit card guarantee may be required for the reservation, depending on the chosen date, room and price.
Arrival, opening hours Arabic - Saudi Arabia and English languages are spoken by the personnel.
RADISSON BLU ABU DHABI YAS ISL Abu Dhabi rooms Rooms
- Please select a date to see the proper prices!
Accommodation services
Organized sightseeing nearby, Car rental nearby
- Wellness section, relaxation
- Finnish sauna
- Jacuzzi
Bar, Cafe, Elevator
Own restaurant


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Daytime running lights are mandatory even during daylight hours
Safety equipment for cars Warning triangleFire extinguisher - only buses
Mandatory use of winter tyres From 1 December to 31 March, if the Swedish Police decides there are wintry conditions on given roads. Studded tyres may be used from 1 October to 15 April.
Safety equipment for cyclist Helmet (compulsory for children under 15)
The information on this website according to Article 8(1) of the road safety directive (Directive 2015/413/EU) is provided by the national authorities in the country concerned. In the event of any conflict between the provided data and the rules in effect in a given country, the latter take precedence. The data are meant purely as a documentation tool and the Commission does not assume any liability for their content or their accuracy.


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The following diagram details the development options available in SharePoint Online (Beta): use the server object model available to sandboxes solutions, or employ the client object model and client-side code to access additional data that is available through the SharePoint web services, or data from external sources.
In SharePoint Online, subscribers own and administer site collections, instead of entire farm installations; therefore, the development approach to SharePoint Online is necessarily scoped to the site collection. Because of this, sandboxed solutions and the client object models form the foundation of developing for SharePoint Online.
A specialized type of the SharePoint solutions framework, sandboxed solutions provide a framework for developers to create, and for SharePoint Online administrators to upload and activate, custom code solutions to SharePoint Online. Sandboxed solutions run in an environment that has access to a core subset of the server object model. The sandboxed solutions framework gives developers access to the major objects at and below the site collection level.
The client object model provides three parallel and comparable representations of the core objects in the server-side SharePoint object model: a .NET Framework managed model, a Silverlight model, and an ECMAScript (JavaScript, JScript) model. This client object models provide remote access to SharePoint data and functionality.
In addition, you can use the client-side code to access the web services that SharePoint Online makes available and external data sources. Because of this, client-side code is a useful option if you need to access either objects beyond those included in sandboxed solutions, but available through a SharePoint Online web service, or external data.
For more information on developing solutions for SharePoint Online, see SharePoint Online: An Overview for Developers, from which this diagram is excerpted.


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Before finding out more about Pacific Assets Trust plc ("Pacific Assets"), it is important that you first read and understand the information set out below. Pacific Assets is an investment trust, incorporated in Scotland with registered number SC091052, whose shares have been admitted to the Official List of the UK Listing Authority and admitted to trading on the main market of the London Stock Exchange plc. Pacific Assets is an alternative investment fund for the purposes of the Alternative Investment Fund Managers Directive ("AIFMD") and acts as its own alternative investment fund manager ("AIFM"). Pacific Assets is registered as a small registered UK AIFM. Pacific Assets has delegated certain portfolio management responsibilities to First State Investment Management (UK) Limited ("First State Investments").
The information contained on the following pages has been prepared for the use of those people who are United Kingdom residents for tax and investment purposes. By proceeding, you are representing that you are not resident in a jurisdiction outside the United Kingdom. If you are unable to make this representation then you should leave this website immediately. First State Investments believes that the information provided is accurate as at the date of its publication, but no representation or warranty of accuracy is given by First State Investments or Pacific Assets and therefore no liability in respect of any error or omission by a third party is accepted by First State Investments, Pacific Assets or their affiliates or any of their directors, employees, consultants or agents.
The information contained in this website is subject to change without prior notice and is not to be reproduced, copied or otherwise made available to persons other than those for whom it is intended, especially anyone outside the UK for tax or investment purposes, without the prior written consent of First State Investments.
This website and its contents have been issued and approved by First State Investments (UK) Limited. First State Investments is authorised and regulated in the United Kingdom by the Financial Conduct Authority. Any comments expressed reflect the views of First State Investments and should not be taken as any kind of recommendation or advice.
Please remember that the value of investments and the income from them may go down as well as up and that you may not get back the amount you originally invested.
Past performance is not necessarily a guide to future performance.
Changes in exchange rates will affect the value of investments overseas. Gearing, where borrowing is used to fund further investment, can increase the returns in rising markets and decrease the returns in market downturns.
Shares in Pacific Assets Trust Plc have not been and will not be registered under the United States Securities Act 1933 (as amended). The information in this website is not intended for distribution and does not constitute an offer to sell or the solicitation of any offer to buy any securities in any jurisdiction in which such offer, solicitation or distribution would be unlawful including but not limited to the United States of America or for the benefit of any United States persons. Investments in emerging markets may involve a higher risk than investments in more developed markets. Investors should consider whether or not an investment in funds or companies which invest in such markets is either suitable for or should constitute a substantial part of an investor's portfolio.
Investments in Pacific Assets may be less liquid than the securities of a larger company, or an investment trust which invests in larger companies, or in more developed economic regions. Securities in smaller companies or an investment trust (such as Pacific Assets) which invests in emerging markets may possess greater potential for capital appreciation, but also involve risks, such as limited product lines, markets and financial or managerial resources and trading in such securities may be subject to more abrupt price movements than trading in the securities of larger companies.
If you are in any doubt about any of the information on this web site, please consult your independent financial or other such adviser authorised to give investment advice under the Financial Services and Markets Act 2000.
First State Investment's regulator, the Financial Conduct Authority, also has a website.
Cookies are small data files that are sent to and stored on your computer, smartphone or other device used to access the internet, whenever you visit a website. First State Investments use cookies to enable and improve certain functions on its website and gain feedback on how its website is used. If you choose to switch certain cookies off, it may affect how this website works.
When you enter First State Investment's website, you will be asked to accept some Terms and Conditions and a cookie will remember if you have accepted them. This means that you don't have to re-accept them on every visit. The cookies used here are 'persistent' as they remember your preferences. Every time the Terms and Conditions are amended, or on an annual basis, a new cookie will be set and you will be asked to re-accept the Terms and Conditions.
First State Investments use analytics cookies to collect information on website activity (such as the number of users who visit our website, the date and time of visits, the number of pages viewed, navigation patterns, what country and what systems users have used to access the site and, when entering the website from another website, the address of that web site). This information on its own does not identify an individual but it does provide First State Investments with statistics that can be used to analyse and improve its website.
These cookies are 'session' cookies.
The browsers of most computers, smartphones and other web–enabled devices are usually set up to accept cookies. If your browser preferences allow it, you can configure your browser to accept all cookies, reject all cookies, or notify you when cookies are set.
Each browser is different, so check the "Help" menu of your browser to learn about how to change your cookie preferences.
However, please remember that cookies are often used to enable and improve certain functions on this website. If you choose to switch certain cookies off, it may affect how the website and certain functionality works.
More information about cookies can be found on allaboutcookies.org
An internet and telephone dealing service is available through the Company's registrar, Equiniti. This provides a simple way for UK shareholders of Pacific Assets Trust plc to buy or sell the Company's shares. For full details and terms and conditions simply log onto www.shareview.co.uk/dealing or call 08456 037037 between 8.00am and 4.30pm Monday to Friday. This service is only available to shareholders of Pacific Assets Trust plc who hold shares in their own name, with a UK registered address and who are aged 18 and over.
Shareview Dealing is provided by Equiniti Financial Services Limited which has issued and approved the preceding paragraph. Equiniti Financial Services Limited, Aspect House, Spencer Road, Lancing, West Sussex BN99 6DA is registered in England and Wales with number 6208699. Equiniti Financial Services Limited is authorised and regulated by the Financial Conduct Authority.
AJ Bell Youinvest
Alliance Trust Savings
Barclays Stockbrokers
Charles Stanley Direct
Club Finance
Fast Trade
Halifax Share Dealing
Hargreaves Lansdown
IG Index
Interactive Investor
James Brearley
Natwest Stockbrokers
Saga Share Direct
The Share Centre
Saxo Capital Markets
TD Direct Investing
Past performance is no guarantee of future performance.
The value of your investment and any income from it may go down as well as up and you may not get back the amount invested. This is because the share price is determined by the changing conditions in the relevant stockmarkets in which the Company invests and by the supply and demand for the Company's shares.
As the shares in an investment trust are traded on a stockmarket, the share price will fluctuate in accordance with supply and demand and may not reflect the underlying net asset value of the shares; where the share price is less than the underlying value of the assets, the difference is known as the 'discount'. For these reasons, investors may not get back the original amount invested.
Although the Company's financial statements and other data are denominated in sterling, it may invest in stocks and shares that are denominated in currencies other than sterling and to the extent they do so, they may be affected by movements in exchange rates. As a result, the value of your investment may rise or fall with movements in exchange rates.
Investors should note that tax rates and reliefs may change at any time in the future.
The value of ISA tax advantages will depend on personal circumstances. The favourable tax treatment of ISAs may not be maintained.


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Coalesse is an award-winning furnishings manufacturer with designs that cross over flawlessly between offices and homes, meeting rooms and social spaces, and private lounges and public places.
Contract Highlights:
- Thoughtfully crafted furnishings that provide comfort and function
- Sophisticated, contemporary styles that perfectly complement any space
- Carefully designed furniture that encourages collaboration and creativity
Coalesse is available as part of E&I's ESM and JAGGAER (formerly SciQuest) offerings.
E&I Coalesse Contract
Getting Started
E&I members can begin using the contract immediately. See the Ordering Information section for details.


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Original paper
Zeolite chemistry and distribution in a Neapolitan yellow tuff deposit
De'Gennaro, Maurizio; Petrosino, Paola; Conte, Maria Teresa; Munno, Rοsalba; Colella, Carmine
European Journal of Mineralogy Volume 2 Number 6 (1990), p. 779 - 786
25 references
published: Dec 19, 1990
manuscript accepted: Sep 18, 1990
manuscript received: Mar 14, 1990
DOI: 10.1127/ejm/2/6/0779
ArtNo. ESP147050206005, Price: 29.00 €
Abstract Through systematic sampling in a quarry of Neapolitan yellow tuff, the stratigraphic variation of both abundance and chemical composition of zeolites (mainly phillipsite and chabazite) has been analysed. The natural zeolitization process is discussed on this basis, with regard to the possible emplacement mechanism of the original volcanic material. Variable relative abundance of zeolites throughout the deposit restricts its uso to applications where only general zeolite properties are required, or where phillipsite and chabazite show the same behaviour


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buy.at US recently ran a competition where all brand new buy.at affiliates that signed up and generated an approved sale were eligible to win the following:
- A platinum pass (worth ~$1,200) to Affiliate Summit East in New York City!
- $500 cash to help with travel expenses or to spend on their hearts desire
We are pleased to announce that the winner is Barefoot Benny (www.barefootbenny.com)! Congratulations Benny were looking forward to seeing you at Affiliate Summit East in August.
-buy.at US


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0cm4 Trailer (2001)
14 July 2001 22 mins
A Japanese indie film, Ocm4 is the philosophical story of a color-blind man called Maeda (Masatoshi Nagase) who decides to have an operation to cure his vision. The problem is that he is not quite sure if he wants to do it, as he thinks that everybody else in the world sees things differently. He's afraid that after the operation, his world is not going to be the same.
Watch the official 0cm4 2001 trailer in HD below or find more 0cm4 videos on Vidimovie.


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Medaille senior Arria Copeland discusses what she loves about the English program, and the Medaille experience.
English program director Dr. Mary Louise Hill discusses her background, and how an English degree led her down a unique and unexpected path.
Medaille professor Dr. Keith Klostermann has been selected to serve on the editorial board for the Journal of Drug and Alcohol Abuse.
The Medaille College Mavericks men's soccer team finished the 2017 season with an AMCC Championship and a spot in the NCAA Tournament.
Article Written by Medaille Professor and Local Psychologist to Be Published in Austin Addiction SciencesAn article by Medaille College professor Dr. Keith Klostermann and a local psychologist has been selected for publication in Austin Addiction Sciences.


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BuDhaGirl Ombré Bangles are colorful orbs of style. Add them to each and every one of your bangle stacks; they instantly turn your wrist into a chic rainbow of color. Choose blue for healing and metabolic control, orange for warmth and attraction, and pink for friendship and joy. I simply love accessorizing with a monochromatic range of color from light to dark…that's what Ombré means. Our Ombré Bangles are weightless, soundless and TSA proof.
• Handcrafted in Rajasthan, India
• Twelve bangles per set
Mindful Glamour Ritual:
Pause. Breathe. Know that as with ombré colors so do our emotions have range. Choose your color today. Then…Go. Be it.
Thought: "How many colors are there in a field of grass to the crawling baby unaware of 'green'? How many rainbows can light create for the untutored eye." Stan Brakhage