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There is only so much you can learn from books and lectures. It is when you have a true experience that knowing occurs. Surrounded by a flurry of paper scraps, Elmer's glue, and scissors, I learned the ugly truth about beauty. The task that was given to the girls I was working with was quite simple, create an inspiration board using the images from stacks of magazines. After the hour was over, all of the girls had an opportunity to share their boards with the rest of the group. One of the girls had a particularly empty board filled with very few images cut from magazines, for which she compensated with her own drawings. "I couldn't find me" she exclaimed. After receiving blank stares, she again blurted out "I couldn't find myself. There are aren't any Black girls in these magazines."
Even though I had done my due diligence speaking with the girl of her experience, discussing what that meant for the rest of the group, and alerting the staff, her words did not leave me. Had I ever been unable to "find myself"? Having dark hair and dark eyes, I have certainly been aware of the "lighter is prettier" standard that prevails in our culture, but aside from the occasional comments from strangers that I might be lucky enough to have children with blond hair and blue eyes rather than my brown hair and eyes and a lame lyric about the beauty of light eyes and hair over dark, I still could find images of those who looked like me. I had Cindy Crawford, I had Snow White, I had Van Morrison's Brown Eyed Girl! I could always see "me" in the pages of a magazine, on an ad, or across the TV screen. If I had to make an inspiration board from those magazine stacks I could find hundreds images with "me"...but she could not.
This vicarious experience stayed with me through the years until it was again raised after Satoshi Kanazawa's blog on Psychology Today stated "black women were rated less physically attractive than other women." Just putting aside flaws of the study, subjective nature of participants, and intent of the author, where was the sensitivity? I imaged the little girl I had worked with after years of subtly being told she was not enough through omission having that confirmed by Kanazawa's commission. Amidst my frustration I turned to Dr. Serena Butler-Johnson, a licensed psychologist in Washington, D.C. for some answers.
Butler-Johnson noted the continued experience of invalidation this little girl encountered even in the twenty-first century, which happens more frequently than we realize among African-American girls. These invalidating experiences are multilayered occurring in the mainstream media, in the home, and among peers. She points out that although our understanding of attractiveness or desirability come from multiple sources, we cannot discount the messages we receive from our external environment as a primary contributor to our understanding of what is beautiful. In our examination of these messages, actively questioning the standard is just as important as identifying their subtle presence.
She states that, "African-American women and those in other minority groups are seldom featured as representations of beauty in American pop culture." Women such as Jennifer Aniston, Angelina Jolie, and Charlize Theron tend to occupy those roles in television, movies, and fashion. She believes that when African-Americans are in these roles, the women often have Eurocentric features, such as Halle Berry and Zoe Saldana, which further reinforces the dominant culture beauty ideals. Without external validation, young children and women can internalize "narrowly defined conceptions of beauty," resulting in feelings of inferiority, confusion, and exclusion.
Moving to the home, Butler-Johnson states deeply ingrained beliefs that "lighter is better" are often passed through the generations, in many minority communities. Discussions about "good hair" versus "bad hair" and being encouraged to stay out of the sun are ways that an African-American child may learn that she is not as pretty without "straight hair" or "light skin." For younger females, in addition to difficult developmental issues, the school environment and peer environment can contribute to a negative understanding of beauty as an African-American. For example, Butler-Johnson believes it is not uncommon for African-American children to be teased by other African-American children about their skin tone or hair.
Dr. Butler-Johnson does suggest ways to counter the negative images surrounding African-American beauty. The primary goal of any intervention is to identify and explore the messages, standards, and images we receive that are deemed beautiful. Additionally, any beauty practices we engage in, whether it is straightening our hair or avoiding the sun, should be motivated from an internal place of health and self-acceptance. Whether working with your child or grappling with your own beauty constructs, Butler-Johnson believes that you must accept, and validate your appearance and those that do not follow the "standard." She feels that you should explore and examine your own biases when it comes to your understanding of attractiveness, and the societal roots of these biases. After you have reached understanding, it is time to challenge these biases by broadening your definition of beauty adopting a global perspective. Incorporating diverse images at home is an effective way to balance the beauty message.
Butler-Johnson feels that the African-American community is continuing to redefine beauty standards. This requires identifying the ingrained beliefs about beauty held deep in the psyche and conflicting messages about beauty (including the skin bleaching ads following articles about embracing ethnicity in African-American magazines). The cracking open of beauty messages and the identification of what is found there can only lead to change, which I hope the little girl with whom I worked will someday find.
Contact Dr. Butler-Johnson: firstname.lastname@example.com
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Myanmar Explorer
18 days tour from £4180
Introduction - Myanmar Explorer
This varied itinerary covers Myanmar's classic sights, and includes a few side trips to lesser known, rural destinations, market towns and ethnic minority villages.
Starting in Yangon, spend some time to get to know the bustling city, before flying north to Mandalay, and heading out to the refreshing hill-station of Pyin Oo Lwin. After some time exploring the town and surrounds, continue further into rural Shan state over the impressive Goteik viaduct, and spend some time in the remote town of Hsipaw, exploring the lush surrounding countryside. Return to Mandalay where the focus will be on the ancient capitals surrounding the city.
Travel to Bagan the exciting way, going via Monywa, and travelling the last part by boat along the Ayeyarwady. Become an explorer in Bagan, where the hundreds of temples and pagodas will amaze you, before travelling onto Inle Lake where you have time to relax and take in the scenery and serenity of the area. Fly back to the UK via Yangon.
Travel Arrangements
You travel independently on a departure date of your choice. Internal travel is by boat and air-conditioned car.
Meal Plan: Bed & breakfast

subset: commoncrawl


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Andrew Lloyd Webber: Masterpiece Trailer (2001)
"andrew lloyd webber Live From The Great Hall Of The People: Beijing" 30 September 2001 125 mins
September of 2001 saw the ground breaking introduction of musical theater to China, with MASTERPIECE - THE MUSIC OF ANDREW LLOYD WEBBER presented at The Great Hall of the People. This spectacular live concert stars Elaine Page and recording sensation Kris Philips (Fei Xiang) together with an international ensemble cast and sixty piece orchestra. MASTERPIECE - THE MUSIC OF ANDREW LLOYD WEBBER includes performances of many hits from his internationally acclaimed productions including CATS, THE FANTOM OF THE OPERA, EVITA and JESUS CHRIST SUPERSTAR. Be a part of this truly historic Masterpiece that is THE MUSIC OF ANDREW LLOYD WEBBER, live in Beijing.
Watch the official Andrew Lloyd Webber: Masterpiece 2001 trailer in HD below or find more Andrew Lloyd Webber: Masterpiece videos on Vidimovie.


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With today's announcement from Auburn Hills and Tokyo that Chrysler and Nissan would trade product for product, the speculation on more deals between the automakers grew louder. Earlier this year, the two automakers outlined the basics of the deal, which had Nissan producing a compact car for...Read More»
The new 2009 Acura TSX goes on sale at the end of the month, and Honda's upscale brand and its upscale managers have tagged it with a price of $28,960, not including destination charges of $715. That's for the base manual-transmission version. Acura says the TSX with the Technology Package and...Read More»
Automotive News is reporting this morning that the ultra-exclusive, ultra-hyped Bugatti Veyron is getting a targa version. A source told the weekly auto newspaper that the Volkswagen-affiliated supercar maker is offering a targa version, instead of a full convertible, because no other solution...Read More»
The wonders of iTunes will never cease. Now, even if you can't actually own a Lamborghini of any stripe, you can see and hear them through Apple's world-dominating music service. Lamborghini's made the play on iTunes with a new podcast called "The World of Lamborghini." If you think that's a snug...Read More»
Toyota and Subaru are so much in love, they're getting together to build a new rear-drive coupe. Because, you know, the world didn't get enough of the Corolla GT-S the first time around. Honda Pilot pics swept the Web this week, days before all the reviewers posted their opinions. Well, you checked...Read More»
What's the most recycled thing you can think of? Plotlines on Family Guy? We've got one better for you -- automobiles. The Automotive Recyclers Association says cars and trucks are the most reused things in America. The association, using data from the Environmental Protection Agency, says that 95...Read More»
Scion's released prices for their 2009 xB and tC models. The only change the xB has undertaken is in color: Stingray Metallic will replace Nautical Blue. With a five-speed manual transmission, the xB starts at $15,750. Shoppers who want a four-speed automatic are ready to go at $16,700. Both prices...Read More»
Alpine's latest car stereo may just be the single piece of equipment you need to live in the digital age -- possibly, even, to live in your car. Well, maybe not to live in your car, but certainly to turn your car into a media center that's missing only 8-tracks, LPs and 45s in its laundry list of...Read More»
If you didn't get enough of Disney's animated take on the fables of Route 66, you're in luck. The company's Pixar unit is brewing up another installment of its Cars franchise, with the new animated feature due in 2012. Autoblog doesn't have many other details about Cars 2, other than it's following...Read More»
Back in March, we told you that the 2009 BMW Z4 would be getting a retractable folding roof. This week some of the other blogs are picking up on the detail, with a little more information on the new Z4's powertrains. The new Z4 is expected to offer a choice of more powerful engines. Riding on the...Read More»
Lamborghini's planning one final edition of its Murcielago supercar -- and Britain's Autocar magazine reports that it will be the first rear-wheel-drive Murc to appear in the Lambo lineup. Set for launch later this year, the new SV edition will be spun from the current LP640 edition of the...Read More»
This car rivaled the finest Duesenbergs and Cadillacs of its day. Based on an Indy car, it was the car that hustled across country in a noteworthy, record-setting drive that inspired a few movies. It was a status symbol for rich drivers until the Depression. A later revival of the car proved...Read More»
Mercedes-Benz hasn't sold a car with a four-cylinder engine in the U.S. for the past few years, but they're taking this sesquicentennial anniversary of the birth of Rudolf Diesel to introduce a new oil-burner engine. The new diesel, Mercedes says, outstrips all its previous efforts in design...Read More»
I'm not the world's biggest fan of the BMW X5 sport-utility vehicle, but the new X6 has me intrigued. This week I have the new "Sports Activity Coupe" in my driveway and I'm going to figure out before Sunday afternoon exactly what the appeal might be. It has to start with the styling, I think. I...Read More»
Once again, TheCarConnection.com's spies have stumbled upon the 2010 Buick LaCrosse -- but this time they managed to get some interior views, as well as (for the first time) a look the production exhaust tips. Looking closely, it appears the new LaCrosse will have some Enclave-like styling cues...Read More»
Adult commuters aren't the only ones being stung by higher gas bills. A report from CNN today shows how the rise in gas prices is affecting every pore of the economy -- right down to how our kids are getting back and forth to school. Take the Dubuque County, Iowa, school system. CNN reports that...Read More»
Earlier this year, we showed you the concept version of Fisker's new Karma plug-in hybrid. Now Fisker's going ahead with plans for production next spring -- and a plan to sell its cars in Europe, too. Like the electric Tesla Roadster that's making the trip across the Atlantic next year, the Fisker...Read More»
UPDATE: Automotive News is reporting that Toyota has confirmed the arrival of both sportscars for 2011. When Toyota bought into Subaru a few years ago, auto pundits assumed that the companies would start sharing brainpower at some point. Now Britain's Autocar magazine says it has the first evidence...Read More»
The Insurance Institute for Highway Safety says sedans are getting more safe. The IIHS, which is underwritten by the insurance industry, crash-tested seven '08 mid-size sedans for front, side and rear impacts in its most recent testing. The sedans -- Chevrolet Malibu, Dodge Avenger, Infiniti G35...Read More»


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Dress // Thrifted
Tights // Hue
Boots // L & T
Glasses // Carol's Dream Boutique on Etsy
Listening to // Bratmobile
I've been having such a productive couple of days! I'm quite proud of myself. I made new buttons for my shop, I cleaned and organized, blogged a ton.. I'm feeling pretty good about this week so far. I'd like to thank : coffee.
I was totally inspired by Allison Wolfe from Bratmobile's style today, with my fake-ass cat eye glasses and my 90 thrifted dress I got the other day, which is about as cheap polyester feeling as ever, but hey, it fits great. I be feelin' pretty cute :)


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text: Shop our home organization and storage event for great savings on storage solutions for all around your home. We've got a ton of options get your home organized and keep it clutter-free, from storage totes, bins, and folding tables & chairs, to shelving units, garage storage, closet storage organizers, and more. And, you'll always find the best selection and value year-round on moving supplies and all your home organization needs.


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We welcome Subotnick Professor of Law Anita Bernstein, Brooklyn School of Law, for a Margot E.
The Fortier Chair in International Arbitration and International Commercial Law, the Private Justice and the Rule of Law research group, and ILA Canada invite you to a talk by Senior Wainwright...
The Fortier Chair in International Arbitration and Commercial Law, and the Private Justice and the Rule of Law research group welcome Jeffery Commission, Sen
How can rule of law, access to justice and good governance contribute to sustainable development in Canada and our world, in the face of rising intolerance and populism?
The Centre on Human Right and Legal Pluralism presents a panel on the rights of Indigenous children with disabilities in Canada, with Dr.
The Constitutional Ciné-club and Professor Johanne Poirier invite you to movie screening for the occasion of the 150th anniversary of the Canadian confederation.
The RGHL Annual Lecture in Health and Law, hosted alongside University of Montreal's Canada Research Chair in Collaborative Culture in Health Law and Policy, will be presented by Geneviève Schamps,...
The Labour Law and Development Research Laboratory (LLDRL) Speaker Series and the Canada Research Chair in Transnational Labour welcome
This McGill Law Journal (MLJ) symposium explores the complex interaction between law, society, and the environment.
For International Women's Day, we invite you to join us for a panel discussion with Indigenous women.


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- List your item for as little as $25 - Advertise your item in both Trade-a-Boat magazine and online
Place your advertisement
- Manage unlimited online ads with TraderAds - Call us today to discuss how we can help you sell more stock
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With the range to reach anywhere in the Pacific, this Maritimo M70 Motor Yacht is ready to slip lines and disappear off the chart
Most boat builders take a proven great hull and stretch it for all they're worth. Not Whittley – meet the two-foot shorter Sea Legend, the SL 20+MORE
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Power and sail tests
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The Ultimate in Sports Family Ski Boats with Style, Brilliant Handling and Superb Finish. You Will Be The Envy Of All Your Friends When You Rock Up To The River With Your New GTO. Book A Test Drive Today
Stephens GTO 2009 Model, Red, White and Grey Custom Gelcoat with Off White and Red Vinyl Interior, Adjustable Drivers Seat with Arm Rest, Mercruiser Gauges, Complete with a Smart Craft Digital System View Gauge, Hour Gauge, Hand Throttle, Fusion Sound System and Remote, Tournament Centre Ski Pole, High Pole and Barefoot Bar, Navigation Lights, Drink Cooler, Bilge Pump. Fitted with a 2009 Model Mercruiser 350 377 Black Scorpion EFI Engine with F/N/R Transmission, Genuine 63 Hours, Complete with a OJ 4 Blade Propeller. 2009 Model Easytow RB20T Galvanised Tandem Trailer with Trailer Fully Decked with Carpet and Board. Complete with Full Boat Cover, Side Skirts and Bimini Canopy.
This Boat is in Immaculate Condition, Has Always Been Garaged and Used in Fresh Water. Price Includes Boat and Trailer Registrations and Safety Gear.
Sale Price $38,990.00
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By Taran Adarsh, IndiaFM
Is Shilpa Shetty quitting Hindi movies? That's the talk going on within the industry. What could've prompted people to believe that Shilpa is quitting Bollywood? Shilpa hasn't signed any new film since the past few months. That, in turn, may've aggravated the talk. Also, there're all kinds of rumors about Shilpa shifting to London to pursue an international career.
We catch up before she's ready to board the flight to Australia for the pre-release promotions of her new film METRO. "I am not quitting movies. But, yes, I am not doing as many films right now. I've completed METRO and APNE [Anil Sharma]. There's no film on hand at the moment, but these two films should keep me in public memory for a year at least," Shilpa tells me.
What prompted the go-slow attitude? "I've always operated that way. There're offers aplenty, but I am in no mood to do mediocre films. The only film I've signed is a British production. You need to enjoy your work. Like METRO. I've pleasant memories of this film," Shilpa smiles.
Is METRO special? "Yes, it is. Even if BIG BROTHER wouldn't have happened to me, I'd still maintain that a film like METRO would put me on a different pedestal. It's one of those unpretentious movies that come rarely to an actor. Like PHIR MILENGE. The sad part is that PHIR MILENGE didn't work, but METRO will. I'm very, very confident of its success," she states, adding that METRO will be a landmark film in her career.


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well I gave it a chance.. It was not as frantic as I thought it was going to be. The level of cooking was so low that it seemed like a PTA fund rasier skit night. I liked that judge was blind to the game.
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More than two decades before Tex McIver was involved in what he calls the "tragic" accidental shooting of his wife, he was indicted by a grand jury in charges related to another shooting.
According to court documents obtained by 11Alive News and confirmed by witnesses involved in the 1990 case, McIver was indicted by a DeKalb County Grand Jury for aggravated assault, criminal damage to property, and possession of a firearm during the commission of a crime.
According to the indictment, he endangered the lives of three teenagers by firing shots into a Ford Mustang they were in on February 27, 1990.
The police report indicates three neighborhood young men were sitting in the car near McIver's house late one night when McIver arrived home and let his dogs out.The 18-year-old and 20-year-old reported to police McIver came out of his house with a gun, fired two shots into the air, then fired two more shots at the vehicle as they fled. They said one of those bullets hit the the gas tank. No one was injured. At the time, one of the teens told police his mother was friends with the McIvers.
According to police reports, McIver denied firing a weapon but said he chased the teens on foot because he was worried about burglaries in the neighborhood.
MORE | High-powered Atlanta couple involved in fatal shooting
PHOTOS: Diane McIver
The charges were dropped in September of 1991. According to court documents, "the victims do not wish to prosecute. The defendant has paid restitution to the victims."
11Alive's Val Hoff contacted one of the victims who confirmed the matter was handled privately but declined further comment.
McIver's attorney, Stephen Maples, says his client felt threatened at the time of the 1990 shooting. According to the police report, "He said he was worried about burglaries and vandalism in the neighborhood".
Maples said the teen's parents pushed for charges to be filed at the time, but later dropped those charges. McIver paid $2,931 to repair damage to the Mustang caused by the gunshots.
Tex McIver underwent a psychological evaluation at the time, where we was found to not have aggressive tendencies.
Twenty-six years later, McIver's wife Diane was shot while sitting in the passenger seat of their car. Tex was sitting in the back, and their best friend, Dani Jo, was driving. They were traveling near Piedmont Park in Midtown.
PHOTOS | Diane McIver memorial images
Tex told 11Alive News he fell asleep holding a gun while in the back seat. He says he woke up minutes later and realized he had accidentally fatally shot his wife. Dani Jo drove them to Emory University Hospital. Diane McIver was rushed into surgery, but did not survive.
An autopsy report says Diane died from a gunshot wound to her back. That bullet, according to the report, traveled from right-to-left, back-to-front, and downward.
Thursday, Maples said Diane was conscious after the shooting. He says the drive to Emory University Hospital took just five minutes.
Tex McIver says he's passed a polygraph about what happened that night.
A spokesperson with the Atlanta Police Department said, "our homicide investigators are working diligently" as they continue to investigate the case.


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I'm so excited to share a new series with you today! If you haven't figured this out yet by the name of my blog, I'm kind ofFrye "Melissa Button Boots" in the cognac color forever, but I'll try to keep it short. I got these boots as a Christmas gift three years ago, and they remain one of my absolute favorite things in my wardrobe today. They're comfortable, stylish, and they honestly look even better today than they did when I first started wearing them- they look just slightly worn in, but in a good way, not a "worn out" way. They're pricey, and I know they're not in every budget, but I promise you, if you save your pennies to purchase these boots, you won't regret it! I'm thinking I should start saving for the gorgeous black pair, too- that's how much I love these boots!
obsessed with dedicated to finding the best of the best of different products, no matter the "type" of product- from home goods, to stationery, to the best mascara you'll ever try. And once I find those things, I tend to be very product-loyal. An example: I've worn the same kind of mascara since I was 17. I decided to start a new weekly column to highlight some of my very favorite things with you, because what fun is finding the best of the best when you don't share the details?! First up on the list: my all-time favorite boots.


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Thaumatin - Chinaprice: contact company for price
and flavour modifier. The substance is often used primarily for its
flavour modifying properties and not exclusively as a sweetener.
The thaumatins were first found as a mixture of proteins isolated from the katemfe fruit (Thaumatococcus daniellii Bennett) of west Africa. Some of the proteins in the thaumatin family are natural sweeteners roughly 2000 times more potent than sugar. Although very sweet, thaumatin's taste is markedly different from sugar's. The sweetness of thaumatin builds very slowly. Perception lasts a long time leaving a liquorice-like aftertaste at high usage levels. Thaumatin is highly water-soluble, and stable to heating and stable under acidic conditions.
Please inquiry for your need now
Company Contact:
- Posted By: Shaanxi Sciphar Hi-tech Industry Co., Ltd.
- Phone: 8602988605679
- Address: Xi'an High-tech Zone CBD core, shannxi xi'an, China
- Email:
Published date: September 7, 2012 -
- Business Description: involved in international trade import export of goods, products, and services
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LuteinGeneral Raw Materials / Natural Resources - Shaanxi Sciphar Hi-tech Industry Co., Ltd. - China - September 7, 2012 - contact company for price
Product Name: Lutein Plant origin and Distribution: Marigold flower belongs to compositae family and tagetes erecta. It is an annual herb and widely planted in Heilungkiang, Jilin, Inner Mongolia, Shanxi, Yunnan , etc.The marigold we used comes from ...
6 BromoandrostenedioneGeneral Raw Materials / Natural Resources - Xianju Medicine Co,.Ltd. - China - September 7, 2012 - contact company for price
6-Bromoandrostenedione CAS number: 38632-00-7 Molecular formula: C19H25BrO2 Appearance: White solid powder 6 Bromoandrostenedione For any questions and needs please contact us below
Grape Seed ExtractGeneral Raw Materials / Natural Resources - Shaanxi Sciphar Hi-tech Industry Co., Ltd. - China - September 7, 2012 - contact company for price
Product Name :Grape Seed Extract Other Name: Red Wine Powder Extract Latin Name: Vitis vinifera L. Specification: Proanthocyanidins 95%, Polyphenol 65% Country of Origin :China Description: Grape Seed extract is an extract from the seeds of grapes. T...
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VideoHive Night Clouds Moon 9595929
Stock Footage \ Nature
Clouds \ Moving \ Similar \ Nature \ Landscape \ Timelaps \ ZoomWonderfull
Stock Footage - Night Clouds Moon 9595929 by rdsmath09 @ VideoHive
Stock Footage \ Nature
Wonderfull time laps of the night sky with a moving clouds. Zoom on the moon.
Similar items : Night, Stars and City
Alpha Channel: No; Looped Video: No; Frame Rate: 25; Resolution: 1920x1080; Video Encoding: Photo JPEG; File Size: 279mb; Number of Clips: 1; Total Clip(s) Length: 0:11.
City Building Traffic; Building Construction; City Building Construction; People Walk in Business City; Crowd People Walk; Flowers Field; Tree Forest.
Keywords: black, blue, clouds, dark, landscape, moon, nature, night, sky, timelaps, tree, view, zoom.


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Dungeon Saga The Quest Continues
Dungeon Saga has really become popular with the guys in my gaming group, so-much-so that over the last few weeks we have not only completed three whole quests, but also gained more players. Taking a break from dungeon crawling this week I thought it would be a good idea to post an update.
Currently the group of heroes are working their way through the nine quests that make up the first book of Dungeon Saga, The Dwarf Kings Quest. So far the group of heroes have only failed to complete one of the quests, as this was a short introduction quest we decided at the time not to replay and get stuck into main adventure.
A lot has happened in these quests, so I figured pictures speak louder than words. With that in mind here are some highlights from the three successfully completed quests in the style of trading cards:
One of the great things about Dungeon Saga is that as the quests grow in size, complexity and difficulty so does your experience and the abilities of the Heroes. A great example of this is that a single zombie troll in the second quest caused no end of problems for the Heroes. However, in the forth quest two zombie trolls and a zombie troll shaman (a character in his own right) were not so tricky to defeat.
So far the Heroes have stood their ground against skeletons, zombies, trolls, banshees and ghosts and are forming a really solid formula of battling through the minions and bosses whilst staying true to the quest. A simple glance at the next quest shows that the dungeon is about to go up a big notch in the quest stakes and might prove to be the first of the main adventure quests that might just beat the group and force a replay.
In conclusion, as a group we are very much loving Mantic Games's Dungeon Quest. One of the group has already picked up a copy of the 'build your own adventures and heroes' expansion that gives you the rules to build and develop your own characters and adventures. We're planning to get stuck into this once we have the first set of adventures completed. At which time I think a few of us will be trading in the standard Heroes that came with the Dwarf Kings Quest to make our own.
If there is one thing this game needs with that starter set is a Dungeon Master screen for the Overlord who controls the dungeon. More than once a surprise has been spoilt by the wondering eye of a Hero player over the Overlords maps and guides. Taking a proactive step, a screen has been purchased for the next quest and our next DM (We take it in turns) is very much in control for the next game...


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access our newsletter archive here
to subscribe enter your e-mail in the left sidebar and click "subscribe".
Our annual events are:
Sausalito Herring Festival – a fun day of food and edutainment
Sausalito Summer Sailstice – Dinner and a Movie in the park
All Aboard! – our mostly annual Fundraising Gala
Other events:
Wooden Boat Oktoberfest – with Spaulding Wooden Boat Center and Resilience Racing
we'd also like to come to your event and have an info booth, maybe even help with certain aspects of your event if it fits our mission.
email email@example.com for invitations and inquieries


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All study at our International School is based on real-world concepts. The experience goes beyond reading about a concept; students are able to see it, manipulate it or participate in it physically. To encourage young children's inquiry through observation, experimentation, questioning and reiteration through
proof-of-concepts; one-day field trips are an essential part of the learning for students in the Primary School.
Teachers use this opportunity to help children demonstrate their trans-disciplinary understanding.
Parents are also encouraged to participate in field trips as volunteers. For students in the higher grades, field trips are an opportunity to experience and demonstrate the inter-connectedness of their learning at school. These may be one-day or overnight trips and are an essential component of the curriculum at AAIS. Often, field trips are also an opportunity for our students in the CIE and IB DP Programme to engage in Creativity, Action, Service.(CAS)


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[foh-toh-ri-frak-tiv] /ˌfoʊ toʊ rɪˈfræk tɪv/
of or relating to a change in the index of refraction by spatial variations of the light intensity, as in a laser.
Tagged: p
Read Also:
- Photorefractive keratectomy
/ˌfəʊtəʊrɪˈfræktɪv ˌkɛrəˈtɛktəmɪ/ noun 1. laser eye surgery that involves scraping away the protective cells of the cornea before reshaping its surface to improve vision PRK
- Photo relief
noun 1. a method of showing the configuration of the relief of an area by photographing a model of it that is illuminated by a lamp in the northwest corner
- Photoresist
[foh-toh-ri-zist] /ˌfoʊ toʊ rɪˈzɪst/ noun 1. Electronics. a photosensitive liquid polymer, used in photolithography to produce integrated circuits.
- Photoresistor
photoresistor (fō'tō-rĭ-zĭs'tər) A resistor whose resistance varies as a function of the intensity of light it is exposed to. Also called photocell. See also photoelectric.


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VERNON - Police are investigating two recent home invasions that may be connected.
Around 7:30 a.m. on Friday, May 8, Vernon RCMP responded to two separate home invasions.
In both incidents people entered the residences, one in the 3900 block of 32 Street and one in the 3900 block of 27 Avenue, while the homeowners were present, RCMP spokesperson Gord Molendyk said in a release issued Monday, May 11.
"Occupants of both residences suffered non life-threatening injuries," Molendyk said.
Police are continuing to investigate to determine whether the two incidents are related.
"The police believe that both incidents were not random in nature and were targeted at specific residences known to the suspects," Molendyk said.
To contact the reporter for this story, email Charlotte Helston at email@example.com or call 250-309-5230. To contact the editor, email email@example.com or call 250-718-2724.


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At Flying Kites in Kenya, we are igniting the potential of vulnerable children.
We believe that providing students with access to high quality education and holistic support is vital to alleviating suffering, increasing gender equality and promoting economic sustainability. By meeting the needs of the whole child, our integrative programs give students the tools they need to build their best lives and positively impact their families, communities and country.
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Why is life worth living? What makes actions right or wrong? What is reality and how do we know it? The Brain and the Meaning of Life draws on research in philosophy, psychology, and neuroscience to answer some of the most pressing questions about life's nature and value. Paul Thagard argues that evidence requires the abandonment of many traditional ideas about the soul, free will, and immortality, and shows how brain science matters for fundamental issues about reality, morality, and the meaning of life. The ongoing Brain Revolution reveals how love, work, and play provide good reasons for living.
Defending the superiority of evidence-based reasoning over religious faith and philosophical thought experiments, Thagard argues that minds are brains and that reality is what science can discover. Brains come to know reality through a combination of perception and reasoning. Just as important, our brains evaluate aspects of reality through emotions that can produce both good and bad decisions. Our cognitive and emotional abilities allow us to understand reality, decide effectively, act morally, and pursue the vital needs of love, work, and play. Wisdom consists of knowing what matters, why it matters, and how to achieve it.
The Brain and the Meaning of Life shows how brain science helps to answer questions about the nature of mind and reality, while alleviating anxiety about the difficulty of life in a vast universe. The book integrates decades of multidisciplinary research, but it's clear explanations and humor make it accessible to the general reader.
"The Brain and the Meaning of Life provides a highly informed account of the relevance of recent neuroscience to human life. It compellingly tells how humans, as biological creatures in a physical world, can find meaning and value." (William Bechtel, University of California, San Diego)
"Engagingly written for general readers, Thagard's book provides a nice description of current knowledge about the brain and explains how brain research bears on philosophical issues." (Gilbert Harman, Princeton University)
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The Venture Bros.
2003, 7 seasons to date
Latest Episodes
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Season 1 Show All Episodes
Episode 0: The Terrible Secret of Turtle BayDr. Venture, his teen sons Hank and Dean, and their bodyguar...Feb 16, 2003
Episode 1: Dia de los DangerousDr. Venture and family are in Mexico where the boys get kidn...Aug 7, 2004
Careers in Science
Dubbed the Ninth Wonder of the World, Jonas Venture's space station, Gargantua 1, has developed a problem, and it's up to Dr. Thaddeus Venture to fix his father's creation. But could the station be haunted by vengeful ghost?225519119
Home Insecurity
Brock goes on a wilderness retreat, and gets more than he bargained for when he encounters the Army searching for something. Meanwhile, the Venture family retreats to the panic room when the forces of both The Monarch and Baron Ünderbheit attack.958238129
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Season 2 Show All Episodes
Episode 1: Powerless in the Face of DeathLife goes on after the tragic deaths of Hank and Dean. Meanw...Jun 25, 2006
Episode 2: Hate FloatsThe Monarch has escaped from prison, and the Henchmen re-ass...Jul 2, 2006
Assassinanny 911
Molotov Cocktease fills in at the Venture compound as Brock goes on a mission to terminate a rogue agent. While Molotov tries to beat some masculinity into Dr. Venture and his sons, we learn something of Brock's past through flashbacks.498119248
Escape to the House of Mummies Part II
Team Venture find themselves trapped in the clutches of a bloodthirsty Egyptian cult and their time machine. Dr. Venture narrowly escapes and teams up with Master Billy Quizboy and Pete White, but promptly forgets to mount a rescue. So it's up to Brock and a pantheon of history's greatest men to find another way out.200229264
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Season 3 Show All Episodes
Episode 1: Shadowman 9: In the Cradle of DestinyThe truths and half-truths about Dr. Venture's former arch n...Jun 1, 2008
Episode 2: The Doctor Is SinDr. Venture learns that a life with no arch enemy is not nea...Jun 8, 2008
The Invisible Hand of Fate
At long last, The Venture Bros. peels away the onion-like shrouds of time for a look back into the troubled past of America's most beloved hydrocephalic former boy genius, to reveal dark secrets that even he didn't know about.84733487
Home Is Where the Hate Is
Dr. Venture receives an unorthodox introduction to his new Guild-assigned nemesis83204895
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Season 4 Show All Episodes
Episode 1: Blood of the Father, Heart of SteelQuestions are answered and truths are revealed.Oct 18, 2009
Episode 2: Handsome RansomThe Monarch attempts to strike Dr Venture where it hurts, by...Oct 25, 2009
Perchance to Dean
Hank, along with is friend, Dermott, start breaking all of the Venture Compound Rules in a bid to get his father's attention.94621358
Return to Malice
Henchman 21, determined to find out who murdered his friend, Henchman 24, kidnaps Hank and Dean and subjects them to the dreaded Chinese water torture. Meanwhile, the Monarch eats a fancy salad and has a reaction to one of the ingredients.843336282
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Season 5 Show All Episodes
Episode 0: A Very Venture HalloweenHalloween Special of The Venture Bros.Oct 28, 2012
Episode 1: What Color Is Your Cleansuit?Dr. Venture hires an army of college interns to help with hi...Jun 2, 2013
Venture Libre
One of Dr. Venture's old inventions seems to have gotten a mind of its own, so General Manhowers sends him to Central America to fix it. The Ventures must all confront their own hearts of darkness if they're to survive what's waiting for them in the jungle.538123108
Sphinx Rising
Henchman 21's command of Team SPHINX is starting to rub the O.S.I. the wrong way, and his new recruits are rubbing them even wronger.84514696
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Season 6 Show All Episodes
Episode 0: All This and Gargantua-2Join the Ventures-and pretty much everyone they've ever cros...Jan 19, 2015
Episode 1: Hostile MakeoverThe Ventures are back! And they're movin' on up to a deluxe...Jan 31, 2016
Maybe No Go
As White & Billy grapple with their arch enemy back in the old 'hood, Doc realizes he can't face his new responsibilities alone when a whale of an enemy shows him how they arch uptown.422546250
Faking Miracles
Doc discovers a mysterious invention that could make or break Dean's chances of getting into college, while The Monarch makes a bad first impression on Dr. Mrs. The Monarch's co-workers.802231257
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The Our Lady of Peace (OLP) junior varsity and varsity players were selected.
The girls recently played in The Lady Falcons Tournament at OLP, which ran Sept. 29 through Oct. 2. Upcoming tournaments this month are the All Saints Tournament Oct. 8 and 9 and the Holy Cross Tournament Oct. 15 and 16. The regular school basketball games start in October.
The team is led by Coach Phil Odom, Coach Bob Mills, Coach Justin Bedford, and Coach Stacy Clum.
Our Lady of Peace junior varsity basketball team, from left, first row, Mya Joie Shimelfenig, Anna Kosierowski, Caroline Stampien and Caroline Murray. Second row, Angelesa DeNaples, Avery McNultey, Stephanie Yatko, Lizzie Pettinato and Coach Justin Bedford.
Our Lady of Peace varsity basketball team members, from left, first row, Coach Phil Odom, Caroline Stampien, Allison Murray, Maggie Mills, Natalie Clum and Lizzie Pettinato. Second row, Coach Bob Mills, Avery McNultey, Campbell Kelly, Stephanie Yatko, Maggie Kosierowski, Clair Marion and Coach Justin Bedford.


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Peritoneal fibrosis (PF) is an important complication of peritoneal dialysis therapy. The present study was performed to examine the mechanisms of PF in view of the plasminogen activator (PA)/plasmin/matrix metalloproteinase (MMP) cascade. PF was induced in tissue-type PA (tPA) deficient mice and wild-type mice by intraperitoneal injection of chlorhexidine gluconate. Mice were killed on day 21, and tissue samples were taken. Histopathological studies were performed. Plasmin activity, gelatinases activity, and the levels of tPA, transforming growth factor-β1 (TGF-β1), and MMP-2 mRNA were determined. Protein levels of MMP-3, tissue inhibitor of metalloproteinases (TIMP)-1, -2, and -3, phospho-Smad3, membrane-type 1 (MT1)-MMP, and MT3-MMP were also studied. On day 21, tPA +/+ mice showed severe PF, whereas tPA −/− mice showed milder change. Submesothelial basement membranes were dissolved in tPA +/+ mice while they were relatively preserved in tPA −/− mice. The levels of macrophage infiltration, staining for α-smooth muscle actin (α-SMA) and collagen type III, and vascular density were all significantly lower in tPA −/− mice than in tPA +/+ mice. The levels of plasmin activity, pro- and active MMP-2, mRNA expression of tPA and TGF-β1, and phospho-Smad3 protein were also lower in tPA −/− mice. No difference was observed between the two groups concerning the protein levels of MMP-3, TIMP-1, TIMP-2, TIMP-3, MT1-MMP, or MT3-MMP. These results indicate that the presence of tPA enhances inflammation, angiogenesis, and fibrogenesis in the peritoneum of the PF model mice. Activation of the PA/plasmin/MMP cascade may play a pivotal role in the pathogenesis of PF.
- plasminogen activator
- peritoneal sclerosis
- transforming growth factor-β1
- peritoneal dialysis
- matrix metalloproteinase
peritoneal dialysis (PD) is an alternative therapy to hemodialysis for patients with end-stage renal disease. However, long-term PD therapy causes chronic injury to the peritoneum, which progressively undergoes marked submesothelial thickening and massive accumulation of collagen (13, 33). This structural alteration, or peritoneal fibrosis (PF), is known to be associated with vasculopathy and neoangiogenesis, which is considered to be a principal cause of ultrafiltration loss, leading to the discontinuation of PD therapy (6, 9, 10). Moreover, among a certain number of patients on long-term PD, peritoneal injury leads to a development of encapsulating peritoneal sclerosis (EPS), a serious complication associated with high mortality (7). To date, the mechanisms of PF and EPS are not fully understood, and no proven therapy has been established.
Tissue-type plasminogen activator (tPA) and urokinase-type plasminogen activator (uPA) are serine proteases that catalyze the conversion of plasminogen to plasmin, a broad-spectrum enzyme responsible for fibrinolysis, direct degradation of extracellular matrix, and activation of metalloproteinases (MMPs) (29, 32). Activation of the PA/plasmin/MMP system may prevent PF by limiting the accumulation of collagen and other extracellular matrixes directly or indirectly via activated MMP. Yet the PA/plasmin/MMP system can also be profibrogenic by activating MMP and transforming growth factor-β1 (TGF-β1), a potent fibrogenic cytokine (11, 32, 39). The expression of tPA is reported to promote interstitial fibrosis of the kidney(36). Activation of MMP-2 is also shown to induce renal fibrosis by promoting epithelial-to-mesenchymal transformation (EMT) (4). The pathological roles of the PA/plasmin/MMP system on the process of renal fibrosis are complicated (39), and even less is known about the process of fibrosis of the peritoneal membranes. In dialysate of PD patients, the levels of coagulation and fibrinolysis-related proteins, including tPA, are known to be high (14). Moreover, the enhanced activation of MMP-2 was noted in the dialysate of patients with EPS as well as in rat PF models (16, 21), and a recent study shows that inhibition of MMP-2 prevents the development of PF in rats (27). The PA/plasmin/MMP system may play an important role in the pathogenesis of PF.
The present study was performed to examine the mechanisms of PF in view of the PA/plasmin/MMP system. PF was induced in tPA deficient mice and wild-type mice by intraperitoneal injection of chlorhexidine gluconate (CG). Our results indicated that activation of the PA/plasmin/MMP cascade is deleterious to the preservation of the peritoneal membranes.
t-PA deficient (tPA −/−) mice on a C57B/L6 background and wild-type C57B/L6 (tPA +/+) mice were purchased from the Jackson Laboratory and were housed in accordance with the National Institutes of Health Guide for the Care and Use of Laboratory Animals. The protocols were approved by the Animal Care and Use Committee of Nagoya University.
Mice PF model.
PF model was induced in mice by the protocol reported previously (18) with a minor modification. Briefly, 9- to 10-wk-old female tPA +/+ mice (n = 6) and tPA −/− mice (n = 6) weighing ∼20 g were administered 0.015 mg/g body wt of 0.1% CG dissolved in 15% ethanol intraperitoneally every 3 days. After 21 days, mice were killed, and peritoneal tissues were obtained for the study. Tissue samples obtained from tPA +/+ mice (n = 6) and tPA −/− mice (n = 6) without CG injection (day 0) served as controls. An additional experiment was performed to obtain the cells in the submesothelial zone from PA +/+ mice (n = 5) and tPA −/− mice (n = 5) with PF on day 21.
Macroscopic pathological studies.
Median laparotomy was performed on day 21, and the macroscopic change in the visceral peritoneum was evaluated semiquantitatively, as described previously (31). Briefly, macroscopic fibrosis/adhesion scores were determined by four parameters, including dullness of the liver margin, area of adhesions, magnitude of adhesions, and ileus appearance. Scores ranging from 0 to 3 points were given to each parameter. Sums ranged from 0 points in the absence of fibrotic/adhesive change to a maximum of 12 points in the severest PF.
Histology and immunohistochemistry.
Parietal peritoneal membranes were obtained for the histological studies. One part of the tissue was fixed in 4% paraformaldehyde, embedded in paraffin, and cut into 4-μm sections. They were deparaffinized and stained with Masson trichrome (28). Sections were also stained for α-smooth muscle actin (α-SMA), collagen type III, laminin, and monocytes/macrophages as described (25, 28). In brief, they were incubated with rabbit antibodies against mouse type III collagen (Cosmobio: LSL, Tokyo, Japan), or laminin (abcam, Cambridge, UK), or rat antibodies against mouse F4/80 antigen (Serotec, Oxford, UK) followed by a conjugate of polyclonal goat anti-rabbit IgG antibodies or rabbit anti-rat IgG antibodies (Cappel, ICN Pharmaceuticals, Aurora, OH). They were also stained with a horseradish peroxidase (HRP) conjugate of monoclonal antibodies (Ab) against human α-SMA (Dako, Carpinteria, CA). The sections were visualized using an avidin-biotin complex kit (Vectastain Elite ABC KIT; Vector Laboratories, Burlingame, CA).
Another part of the tissue was frozen in optimal cutting temperature (OCT) compound (Miles, Elkhart, IN) and kept frozen at −80°C until use. Sections (2 μm thick) were cut with a cryostat, fixed in acetone, and incubated with polyclonal rabbit anti-rat thrombomodulin Ab (25) followed by fluorescein-conjugated goat anti-rabbit IgG Ab (Cappel). Negative controls were performed by the replacement of primary antibodies with isotype-matched or species-matched antibodies.
Morphometric analysis of histology and immunohistology.
Morphometric analyses were performed using an AXIOVISION 3.0 system microscope (Zeiss, Oberkochen, Germany). Fibrotic change was evaluated by measuring the full thickness of the submesothelium on Masson's trichrome-stained sections oriented perpendicular from the top of the muscle layer to the serosal surface as described (23). Inflammatory cell infiltration was assessed by counting the number of F4/80 positive cells (monocytes/macrophages) in four randomly selected high-power fields (×400). The results are shown as number per 0.144 mm2. Neovascularization was evaluated by counting the number of vessels stained with anti-thrombomodulin Ab in 12 randomly selected high-power fields (×400). The results are shown as number per 0.432 mm2. Four high-power fields (×100) from each section were photographed, and areas positively stained for α-SMA or type III collagen in the submesothelial area of the peritoneum (above the muscle layer) were measured by computer-aided planimetry using Mac Scope (Mitani, Fukui, Japan) (22, 28).
Chromogenic assay of plasmin activity.
Plasmin activity of the peritoneum was measured using a plasmin-specific chromogenic substrate, Chromozym PL (Roche Applied Science, Indianapolis, IN), as described (24). This substance is specifically cleaved by plasmin into a residual peptide and 4-nitroaniline, which can be detected spectrophotometrically. Samples (166 μl) containing 400 μg of peritoneal tissue protein, 667 μl of 50 mmol/l Tris (pH 8.2), and 167 μl of chromogenic substrate were mixed in a cuvette. The absorbance was measured at 405 nm twice over a 2-h interval. The increase in absorbance, corresponding to plasmin activity, was calculated. Results were expressed as ratios to a mean value in tPA +/+ mice without PF (day 0).
Real-time RT-PCR.
The expression levels of tPA, MMP-2, and TGF-β1 mRNA were determined by real-time RT-PCR. Whole parietal peritoneal membranes were taken from tPA +/+ mice (n = 6) and tPA −/− mice (n = 6) without PF (day 0) and from tPA +/+ mice (n = 6) and tPA −/− mice (n = 6) with PF (day 21). Total RNA was prepared with TRIzol reagent (Life Technologies BRL, Rockville, MD), followed by further purification using Micro-to-Midi Total RNA Purification System (Invitrogen Life Technologies, Carlsbad, CA). The cells in the submesothelial zone were taken from PA +/+ mice (n = 5) and tPA −/− mice (n = 5) with PF (day 21) as described (20). Briefly, the peritoneal surfaces of the abdominal wall sections were immersed for 15 min in TRIzol reagent. The cells in the submesothelium were gently scraped using a disposable blade, and total RNA was prepared using TRIzol reagent. One microgram of total RNA was reverse-transcribed using Takara RT kit (TaKaRa Biomedicals, Osaka, Japan). Real-time RT-PCR was performed using a SYBR green dye (Applied Biosystems, Foster City, CA) with the ABI PRISM 7500 equipment as described (38). DNA polymerase was first activated at 95°C for 10 min, denatured at 95°C for 15 s, and annealed/extended at 60°C for 1 min, for 35 cycles according to the manufacturer's protocol. The sequences used are as follows: mouse tPA, forward primer 5′-CTGAGGTCACAGTCCAAGCA-3′ and reverse primer 5′-ACAGATGCTGTGAGGTGCAG-3′; mouse MMP-2, forward primer 5′-GGCTGGAACACTCTCAGGAC-3′ and reverse primer 5′-CGATGCCATCAAAGACAATG-3′; mouse TGF-β1, forward primer 5′-TTGCTTCAGCTCCACAGAGA-3′ and reverse primer 5′-TGGTTGTAGAGGGCAAGGAC-3′; and mouse glyceraldehydes-3-phosphate dehydrogenase (GAPDH), forward primer 5′TGCGACTTCAACAGCAACTC-3′ and reverse primer 5′-ATGTAGGCCATGAGGTCCAC-3′. Relative quantitation of gene expression was carried out using the standard curve method (ABI PRISM 7500 Sequence Detection System; Applied Biosystems). Amplicons were run as triplicates in separate tubes to permit quantification of the target gene normalized to GAPDH as a control. Results are reported as relative ratios to the mean value of the tPA +/+ mice without CG injection (day 0) (whole peritoneal tissue), or to the mean values of the tPA +/+ mice with CG injection (day 21) (cells from submesothelium).
Detection of MMP-2 and MMP-9.
Gelatin gel zymography was performed using the extract of peritoneal membrane according to the method described previously (5). In brief, peritoneum lysates were prepared by homogenizing peritoneum with 100 mmol/l Tris·HCl (pH 7.4) containing 1% sodium dodecyl sulfate (SDS), 20 mmol/l NaCl, and 2 mmol/l phenylmethylsulfonyl fluoride. Protein concentration was determined using a Coomassie protein assay. Samples (30 μg protein/well) were loaded onto 10% SDS-polyacrylamide gels containing 1 mg/ml gelatin (Sigma-Aldrich) as substrate. After electrophoresis, SDS was removed from the gel by incubation in 2.5% Triton X-100 at room temperature for 30 min 3 times with gentle shaking. The gel was washed well with distilled water to remove detergent and incubated at 37°C for 48 h in a developing buffer containing 50 mmol/l Tris·HCl at pH 7.6, 0.15 mol/l NaCl, 10 mmol/l CaCl2, and 0.02% NaN3. The gel was then stained with a solution of 50% methanol, 10% acetic acid, and 0.125% Coomassie brilliant blue, followed by destaining in the same solution without dye. Proteinase activity was detected as unstained bands on a blue background representing areas of gelatin digestion. The bands were quantified using National Institutes of Health Image software. Results are reported as relative ratios to the mean value of pro-MMP-2 in the tPA +/+ mice without PF (day 0). Markers for MMP-2 and MMP-9 were purchased from Cosmo-Bio (Tokyo, Japan).
Western blot analysis.
Western blot analysis was performed as described previously (12, 28) with minor modification. Briefly, peritoneal tissues obtained from tPA +/+ mice and tPA −/− mice with PF were homogenized in RIPA buffer using TisseLyser (Qiagen, Hilden, Germany). Fifty micrograms of proteins was separated by 10% SDS-PAGE, electroblotted onto PVDF membranes (Immobilon-Psq; Millipore), and blocked with 5% nonfat milk. The membranes were incubated with antibodies against one of the following molecules: MMP-3, tissue inhibitor of metalloproteinases(TIMP)-1, TIMP-2, TIMP-3, membrane type 1 (MT1)-MMP (Santa Cruz Biotechnology, Santa Cruz, CA), MT3-MMP (AnaSpec, San Jose, CA), or phospho-Smad3 (Rockland Immunochemicals, Gilbertsville, PA). Subsequently, the membranes were incubated with HRP conjugate goat anti-rabbit IgG or rabbit anti-mouse IgG (Cappel). The proteins were detected using an ECL kit (Amersham, Little Chalfont, UK) and quantified using National Institutes of Health Image software. The levels of each protein were normalized to β-actin expression. Results are reported as relative ratios to the mean value of the tPA +/+ mice without PF (day 0).
Statistical analysis was performed using a software program, Stat View 5.0 (SAS Institute, Cary, NC). For comparison of the data between two groups, Mann-Whitney-U test was used. For comparison of data among multiple groups, ANOVA and Fisher's protected least significant difference (PLSD) method were used. Data were expressed as the mean value ± SD. Differences were considered significant when P value was < 0.05. Each experiment was repeated three times with similar results.
Levels of tPA mRNA expression and plasmin activity.
Quantified RT-PCR revealed that the level of tPA mRNA expression significantly increased in the parietal peritoneum after the induction of PF on day 21 (Fig. 1A). Chromozyme assay demonstrated that plasmin activity also increased in tPA +/+ mice on day 21 while it did not in tPA −/− mice (Fig. 1B).
Macroscopic findings.
On day 21, tPA +/+ mice showed a severe macroscopic change with dullness of the liver margin and adhesion of the peritoneal membranes, while tPA −/− mice had only a mild change (Fig. 2). Semiquantitative analysis of the peritoneum showed that the macroscopic fibrosis/adhesion score was significantly higher in tPA+/+ mice than in tPA −/− mice (tPA +/+: 5.42 ± 1.19; tPA −/−: 3.79 ± 0.82; P < 0.05) (Fig. 2).
Morphometric analysis of histology and immunohistology.
Histology showed that the submesothelium in tPA +/+ mice was significantly thicker than in tPA −/− mice (tPA +/+: 178.2 ± 70.6 μm; tPA −/−: 60.7 ± 43.5 μm; P < 0.05) (Fig. 3).
Immunohistochemistry showed that α-SMA was strongly localized in the submesothelial sclerotic zone of the tPA +/+ mice. In contrast, only weak staining was observed in tPA −/− mice (Fig. 4A). A computer-aided quantitative analysis showed that the area positively stained for α-SMA was significantly smaller in tPA −/− mice than in tPA +/+ mice (P < 0.05). Fibrotic change was also evaluated by immunostaining for collagen type III. Positive staining was observed in the fibrotic area of the submesothelial sclerotic zone (arrows; Fig. 4B). The area positively stained for collagen type III was significantly smaller in tPA −/− mice than in tPA +/+ mice (P < 0.05) (Fig. 4B).
Immunostaining for laminin was performed to study the pathological change of basement membranes in the submesothelial tissue. Normal mice showed clear linear staining for laminin beneath a single layer of mesothelial cells (Fig. 5a). In tPA +/+ mice with PF (day 21), the basement membranes were distorted and mostly dissolved (Fig. 5b). In contrast, they were relatively preserved in tPA −/− mice (Fig. 5c).
Inflammatory reaction was evaluated by immunostaining for F4/80 on day 21. The results revealed that the number of monocytes/macrophages in the peritoneum was significantly less in tPA −/− mice than in tPA +/+ mice (tPA −/−: 248 ± 107; tPA +/+: 434 ± 192; P < 0.05) (Fig. 6A). The state of the blood vessels in the peritoneal tissues was studied by staining with anti-thrombomodulin antibodies. The vessels in tPA +/+ mice had a distorted and narrowed lumen while those in tPA −/− were relatively preserved. When the number of number of blood vessels was counted, the vascular density was significantly less in tPA −/− mice than in tPA +/+ mice (tPA −/−: 65.0 ± 19.7; tPA +/+: 95.9 ± 32.7; P < 0.05) (Fig. 6B).
Gelatin gel zymography of the peritoneal tissue.
Gelatin gel zymography was performed on the peritoneal tissues to study the levels of MMPs. Pro-MMP-9 was not detectable in any group of mice. Active MMP-9 had increased on day 21 after the induction of PF, and no difference was observed between the two groups (Fig. 7, A and B). Likewise, no difference was observed in the basal levels (day 0) of pro- or active MMP-2 between the two groups (Fig. 7, A and C). In PF model mice (day 21), pro- and active MMP-2 had significantly increased in the peritoneum of tPA +/+ mice. The level of active MMP-2 on day 21 was significantly lower in tPA −/− mice than tPA −/−, while the level of pro-MMP-2 was not different between the two groups (day 21).
Expression of MMP-2 and TGF-β1 mRNA.
The levels of MMP-2 and TGF-β1 mRNA in the whole peritoneum were studied by quantified RT-PCR. In tPA +/+ mice, the level of MMP-2 mRNA increased after the induction of PF (day 21) compared with the basal level (day 0). In contrast, no significant increase was observed in tPA −/− mice by the induction of PF (Fig. 8A). The expression of TGF-β1 mRNA increased in tPA +/+ mice with PF (day 21) compared with tPA +/+ mice without PF (day 0) or tPA −/− mice with PF (day 21) (Fig. 8B). The gene expression in the cells of submesothelial zone was also studied after the induction of PF (day 21). Both MMP-2 and TGF-β1 mRNA levels were significantly lower in tPA −/− mice than in tPA +/+ mice (Fig. 8, C and D).
Phosphorylated Smad3 in the peritoneum.
Western blotting showed that the levels of phospho-Smad3 protein increased in the peritoneal tissue of tPA +/+ mice with PF (day 21) but not in tPA −/− mice with PF (day 21), suggesting enhanced levels of active TGF-β1 in the former (Fig. 9).
MMP-3, TIMPs, and MT-MMPs in the peritoneum.
No difference was observed between the two groups concerning the protein levels of MMP-3, TIMP-1, TIMP-2, TIMP-3, MT1-MMP, or MT3-MMP in the peritoneal tissue (Fig. 10).
The present study clearly demonstrates that tPA expression when enhanced by the repeated injection of CG exacerbates peritoneal inflammation, angiogenesis, and fibrosis in a mouse model of PF. These data suggest for the first time that tPA is not protective but rather pathogenic to the peritoneal membrane.
To study the mechanisms of the fibrogenic process in the present PF model, we investigated the activity of plasmin, the natural substrate of tPA. We found that plasmin activity in the peritoneal tissue was enhanced by the presence of tPA after the induction of PF. Since plasmin is known to activate MMPs, we then studied the levels of MMP-2 and MMP-9 in the peritoneal tissue. MMP-9 was not detected in the normal peritoneum, and only weak expression was observed after the induction of PF. In contrast, the expression of MMP-2 was clearly detectable in the peritoneum at a basal condition, and both active MMP-2 and pro-MMP-2 had increased significantly in the peritoneal tissue obtained from PF model mice. These results were consistent with previous findings that MMP-2 is elevated in the dialysate of rats with PF (16) and patients with EPS (21) and that the inhibition of MMP-2 prevents PF in rats (27). It is known that the activation level of MMPs is controlled by the MMP inhibitors or MMP inducers. We found that none of the levels of MMP inhibitors, including TIMP-1, -2, and -3, were different between tPA knockout (KO) mice and wild-type mice. No difference was observed in the levels of MMP inducers (MT1-MMP and MT3-MMP) between these two groups. We also demonstrated that MMP-3 levels were not different between the two. Taken together, the data suggest that the net activity of MMP-2 was enhanced, which may play a role in the process of PF development.
Activation of a PA/plasmin/MMP cascade could enhance PF in several ways. First, MMP-2 in the peritoneal membrane is considered to accelerate migration of the fibroblasts and/or inflammatory cells into the submesothelial area (3, 8). We found that the number of macrophages increased in the peritoneum of tPA +/+ mice compared with that of tPA −/− mice. The results suggest that the function of tPA to promote PF may be mediated by the enhanced migration of inflammatory cells. Second, MMP-2 may proteolytically generate active TGF-β1 peptide (4). In our study, the protein level of phospho-Smad3 was higher in the tPA +/+ mice than in the tPA −/− mice on day 21, indicating that the level of active TGF-β1 had increased in the tPA +/+ mice with PF. Third, MMP-2 may have the ability to stimulate angiogenesis (3, 26), providing another explanation for the morphological change in PF model mice. We found that the number of vessels in the peritoneum of the tPA −/− mice with PF had significantly decreased. It is not clear from our results whether angiogenesis is a cause of the PF or merely a result. Margetts et al. (19) clearly demonstrated using an adenoviral vector system that overexpression of TGF-β, a fibrogenic cytokine, induced the expression of VEGF, a key molecule for angiogenesis. It is also reported that inhibition of angiogenesis suppressed PF. These results suggest that angiogenesis and fibrosis enhance each other, causing the further acceleration of PF. Last, MMP-2, activated by tPA and plasmin, can accelerate fibrosis by promoting EMT. Recent studies have elucidated the contribution of the gelatinases, MMP-2 and MMP-9, to the process of EMT (2, 4, 30, 35, 36). The significance of EMT was also shown in the peritoneum of PD patients (34). In our study, enhanced staining of α-SMA and collagen III was observed in the thickened submesothelial area of the PF model mice. Moreover, staining for laminin showed that the basement membrane was compromised and partially destroyed in the fibrotic peritoneum. These results suggest that EMT may actually have been taking place in our study as well. To determine the key mechanism in the process of PF, further studies using genetically modified mice, such as MMP-2 deficient mice, will be useful.
Originally, tPA was considered to attenuate tissue fibrosis due to its potential to degenerate the extracellular matrix (ECM). It was generally accepted that ECM degradation in glomeruli is mediated by a PA/plasmin/MMP cascade (1). It has also been demonstrated that urokinase receptor deficiency accelerates renal fibrosis in the interstitium (37). However, more recent studies have shown that tPA may act as a profibrogenic molecule. In a mouse unilateral urethral obstruction model, tPA was shown to enhance interstitial fibrosis of the kidney (36). In addition, Hertig et al. (15) reported that the deficiency of type 1 plasminogen activator inhibitor (PAI-1) aggravates the course of experimental glomerulonephritis through overactivation of TGF-β1. In the present study, we demonstrated that tPA accelerated the pathological alterations of the peritoneum in a mouse model of PF. Whether the PA/plasmin/MMP system is deleterious or beneficial seems to depend on the specific situation.
One of the limitations of the present study is the model employed. Although a PF model induced by the repeated injection of CG has been used to study the pathogenesis of peritoneal injury (16, 18), the processes could differ significantly from those taking place in actual patients. A PF model induced by the repeated injection of high-glucose solution may better reflect the pathogenesis of peritoneal damage in PD patients (17). However, the relative thickening of the peritoneal membrane in this model is not significant enough to facilitate a study of PF. Further studies analyzing the samples from PD patients will be necessary to clarify the actual role of the PA/plasmin/MMP system.
In summary, the present study demonstrated that mice deficient in tPA showed significantly milder peritoneal change compared with wild-type mice when PF was induced by CG. The results suggest that the presence of tPA enhances inflammation, angiogenesis, and fibrogenesis in the peritoneum of the PF model mice. Activation of the PA/plasmin/MMP cascade may play an important role in these pathological processes.
No conflicts of interest are declared by the authors.
- Copyright © 2009 American Physiological Society


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Gigabyte X79S-UP5 WiFi Intel LGA 2011 ReviewOverclocking »
Drive and Audio Performance ResultsOur drive and audio testing differs a bit from the rest of our testing, for several reasons. First of all, when it comes to drive performance comparison, nearly every platform on the market is very close to one another, as most do provide external drive controllers which means the numbers offered are very much platform agnostic. And finally, with audio, we do not list any numbers except for those reported by the product we are testing in order to provide the most information possible, as each audio CODEC will behave quite differently, and each board does not employ the same CODEC. As such, there is no standard we can use other than the numbers themselves. You can always check our other motherboard reviews in order to make direct comparisons to audio performance.
We tested each drive interface separately in order to provide the most complete numbers possible. Employing HDTune Pro for all of the testing, we tested each drive outside of the OS environment, using a separate OS on a separate drive. However, we do use drives with a fair amount of data on the Corsair ForceGT (60% full) to simulate performance in real-world situations, and I do use the same drive to test all interfaces too.
HDTune Pro (SATA2)
In HDTune Pro SATA 3 GB/s performance, we found the GigabyteX79S-UP5 WiFi to be underperforming. It placed last, but really, it's only about 1% slower than the other results, if that.
HDTune Pro (SATA 6Gb/s)
SATA 6 Gb/s showed much the same, with the GigabyteX79S-UP5 WiFi right in the middle.
HDTune Pro (USB3.0)
USB 3.0 drive performance tests are done using the same Corsair ForceGT drive used to test SATA 3 Gb/s and SATA 6 Gb/s performance, and here we got much better results, with the GIgabyte board taking the top spot.
RightMark Audio Analyzer
Audio testing using RightMark Audio Analyzer provided pretty good numbers for the Gigabyte X79S-UP5 WiFi, rating the audio given by the onboard Realtek CODEC as "Good". Only a single item here was listed as "poor".


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Pure Multi-Family REIT
Pure Multi is a Canadian based, publically traded vehicle which offers investors exclusive exposure to attractive, institutional quality U.S. multi-family real estate assets. Pure Multi focuses on luxury resort-style apartment communities in key sunbelt locations such as Dallas, Houston and Phoenix – markets that consistently rank at the top for both job and population growth for the entire U.S. The strong growth in the sunbelt areas provide the opportunity for our investors to participate in an asset class that is generating above average revenue growth and stable distributions. Pure Multi's units are dually listed in USD (RUF.U) and CDN (RUF.UN) on the TSX-Venture, allowing investors the flexibility of holding units in either currency.
Investment Objectives
Pure Multi's long-term objectives are to:
- generate stable and growing monthly cash distributions on a tax-efficient basis from investments in multi-family real estate properties in major markets in the United States;
- enhance and maximize the value of Pure Multi's assets through active management and improve its properties through targeted value-add capital programs;
- expand its asset base through an accretive acquisition program.


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here is a digi stamp i got from
chris has lots of amazing images there. i loved this one .i loved colouring it :) . the paper is free downloads that i thought went well with it :) .
huggs jo x
that is sooooo pretty, the bp is perfect for the image :-)
Another beautiful card Jo, the backing paper and image are so pretty
What can I say, another lovely one!
Beautiful card Jo, I love how you coloured the window and the paper you used is perfect with it! Whoever receives this card is going to love it! Hugs, Chris x


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Oglethorpe Mall's many neighbors have been gussying up their properties for close to a decade now.
Market Walk is next.
Developers plan to raze seven buildings on the nearly 24-acre site located across Mall Boulevard from Savannah's first megamall and bordered by Hodgson Memorial Drive. Among the buildings to be demolished are the Kroger supermarket, the Days Inn hotel, a mini-storage compound and office and retail center located behind the Kroger.
A larger, single commercial center that will be home to a 117,000-square-foot Kroger and a big-box retailer will anchor the redeveloped center.
The Chatham County-Savannah Metropolitan Planning Commission blessed the project last week, sending it to the Savannah City Council for final approval. Demolition will begin later this summer, but developers won't set a reopening date for the center until commitments and approvals are finalized, according to leasing agent Chris Senn with Blanchard & Calhoun Real Estate.
Kroger will add a fuel center on the property, and the new Market Walk will include two new standalone restaurant/retail buildings. The building that currently houses Fiddlers Crab House and The Original Pancake House will remain.
The new Kroger will be twice the size of the existing store and is nearly 50,000 square feet bigger than the Berwick Kroger along U.S. 17.
The development's leasing agent is negotiating with a tenant for the 55,500-square-feet space next to the Kroger. Reserved for a big box retailer, Dick's Sporting Goods has expressed interest, according to sources.
But the sporting goods chain has yet to commit to the space, Blanchard & Calhoun's Senn confirmed via email.
The planned space fits Dick's profile — their stores average 55,000 square feet in size.
The United States' largest full-line sporting goods retailer already plans to open a store in Bluffton, S.C., later this year and has a history of locating multiple stores within a region to maximize its distribution chain.
Dick's Sporting Goods declined comment on its Savannah plans when contacted Friday through a representative.
Dick's, which started as an outdoors store, would join Bass Pro Shops as sporting goods chains with a presence in Savannah. The first Dick's was a small bait and tackle shop located in Binghamton, N.Y., but it expanded over time to offer products for all sports enthusiasts.
Academy Sports showed interest in a Savannah store in late 2008 but abandoned its plans because of leasing issues.
The Market Walk improvements would be the latest commercial project in the Oglethorpe Mall area. Local developer Melaver Inc. redeveloped the shopping center across White Bluff Road from the mall into Abercorn Common in mid-2000s. Oglethorpe Plaza, located across Abercorn St. from Abercorn Common, is getting a makeover with a Kohl's department store scheduled to open there later this year.
Chatham Plaza, located across Abercorn St. from the Savannah Mall, received a subtle facelift following the departure of Walmart in 2006.


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- Please select a date to see the proper prices!
- Meal can be requested on the spot
Best offer
30.96 € / person / night, no meal
Description of the accommodation:
Rooms, services Are you looking to reserve a room in Thailand? Amarin Victoria Resort Mae Nam is pleased to host guests booking on RevNGo.com. The guests of the hotel may stay in 46 nicely furnished, comfortable rooms in Ban Mae Nam. Since the hotel has an own restaurant, you may also try fine local meals on the spot. If necessary, parking is available nearby. You may take a car rental service or an organized city tour to check the most important tourist attractions. The fans of actively spent leisure time may take the bike rental, billiard, minigolf, water ski, diving, surfing and boat rental opportunities nearby. The bar provides a nice atmosphere for a romantic evening talk or a personal meeting. You may secure your valuables in the safe. At the hotel you may go online via wireless Internet connection (WiFi). You can find the exact list of services provided by Amarin Victoria Resort Mae Nam (including those for extra fees) and the exact equipment of the rooms on the information sheet below.
Payment Advance bank card payment or credit card guarantee may be required for the reservation, depending on the chosen date, room and price.
Arrival, opening hours The earliest arrival time is 14:00, the latest time to leave the rooms is 12:00. The personnel of the hotel can speak in Thai and English with you.
Amarin Victoria Resort Mae Nam rooms Rooms
- Please select a date to see the proper prices!
Accommodation services
Free WiFi in shared places
Relaxation: Billiard, Minigolf, Bike rental at the accommodation
Organized sightseeing nearby, Car rental nearby, Water skiing nearby, Scuba diving nearby, Surfing nearby, Boat rental nearby
- Pool (Outdoor - seasonally open)
Garden, Bar, Elevator, Safe deposit box, Roof garden
Own restaurant
Bathrobe, Hairdryer, Desk in the room, Mini-bar


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Many people think an Interior Designer is simply a decorator that selects wall coverings, fabrics and furniture. That's only part of it. Good, reputable designers also act as a project manager and advocate for you. With how busy everyone's lives are, it is more difficult to find skilled and professional people to successfully complete your project. We lift that burden from you and champion your interests to the contractor, subcontractors, furniture representatives, and everyone!
Sensible Chic is an independent firm so we're not affiliated with a furniture dealer or building developer. There are no conflicts of interest you need worry about. We receive no commissions for any products or services. All of our professional knowledge, experience, and contacts will work in your best interest to give you the most beautiful home you desire. Any furniture dealer can choose some furniture and pick some paint. But as professional interior designers, we emphasize functionality in conjunction with beauty and space planning to meet your budget.
"Because we're acting as independent designers on the client's side there's no incentive for us to diminish quality or push product and furniture lines. We're design-driven," says designer Therese Patterson of Sensible Chic.
Sensible Chic takes a team approach to working with the builder and homeowner, but acts as representative for the client. "Homeowners need an extra set of eyes and an opinion that's on their side. The architect creates plans to communicate with the builder; the interior designer makes sure these plans include what's in the client's heart."
How do we do it?
Interior designers also help clients navigate all of their options. Many people are overwhelmed by dozens upon dozens of choices they have for hinges, drawer pulls, switch plates, light fixtures, tile and more. Once a general theme is established, we then edit the field of finishes so the clients can save time and headache and choose from a handful and not a hundred.
Although many of our clients are referrals, some are not only new to us but have never used an interior designer before. One of the first questions we get asked is "how much will it cost, and how do we get started?"
What is the process?
We start with an appointment to discuss your needs, take pictures and take measurements. The initial assessment meeting usually lasts about an hour to an hour and a half (and varies based on a client's needs). After our assessment we will develop a design plan for your space. You will receive our recommendations on paint colors, floor coverings, window treatments, or whatever other advice you need ~ as little or as much design advice as you require. We will then return to your home to present and discuss our design plan with you. We charge $110/hour plus $40/hour for travel time in the San Diego area. In some cases, that is all the client wants.
In that instance, our clients prefer to pay us for the design plan (which normally takes about 6-8 hours to complete) and then do their own purchasing, construction, hiring and management of subcontractors and installation while referencing the design guide we provide them for material and color selection.
But in most cases, our clients prefer to retain us after the initial consultation, use us to manage their project, and purchase materials, furnishings, and services through us. By having us manage your project it frees you to concentrate on other priorities while we focus on managing the subcontractors, ordering the furniture and fixtures, and making sure every detail is tended to. We get paid directly for these services at the same hourly rate.
Either way you are going to get professional interior design services that will enhance the beauty, functionality, safety, and value of your home. When you are ready to make an assessment appointment, please call us at 858.472.0988 or send us an email or Contact Us and tell us how we can help make your home more beautiful.
Visit our Interior Design Portfolio and enjoy imagining what we could do for you!


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Cap Under Fire: The Budgetary Review And The Cap
During the process of the budgetary review the CAP faces its greatest challenge of its history: not only the (common) financing of the CAP, but the future of the CAP itself is at stake. It is obvious that the reform steps implemented so far – even though they have several forward-looking elements – do not result in a CAP sustainable on the long run. Further changes are inevitable. Basing our analysis on the theories of fiscal federalism and other political economy approaches, we try to answer the following questions. Is common financing of a reformed CAP justified? Can national co-financing be extended? Is it justified to keep the system of commonly financed direct payments?
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We have a large, well-equipped workshop based in Harmill Industrial Estate, just off Grovebury Road, a team of 8 experienced mobile engineers and a comprehensive service department.
We are able to offer a range of repair services whether it be blown bulbs, battery drains, complex fault finding or diagnostic tests.
We pride ourselves on installing the highest quality products from our approved suppliers. Products range from simple dash cameras to highly sophisticated safety equipment fitted to FORS and Crossrail regulations.
Service & Supply of:
- Light Bars
- Reverse Cameras
- Audio Systems
- CB radios
- Hands-free Kits
- Top & Bottom Bars
- Spotlights
- Batteries
- Alternators & Starter Motors
- Dash Cams
- Tracker – Stolen Vehicle Recovery Systems
- Parking Sensors
- Vehicle Safety Solutions
AES Fleet
Improve the efficiency of your fleet and your mobile workforce with TomTom fleet management solution.
AES Climate
Auto Electrical Services are a main agent for Eberspacher, we undertake all installations, servicing and repairs. We are also dealers for other market leaders, such as Dometic, WAECO, Viesa and Telair.
AES Workshop
No job is too big or small, we have a comprehensive service desk and over thirty years experience working with and developing within the industry. We pair old fashioned customer service with cutting edge technology.


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In an interview with Alex Jones, school shooting consultant and former state trooper Wolfgang Halbig claims that Obsidian, a company in Washington D.C., "wrote the script" for the fake Sandy Hook school massacre of December 14, 2012. (See "Sandy Hook massacre was a "contrived event," says former state trooper Wolfgang Halbig")
H/t "Barry Soetoro, Esq."
I don't know how Halbig came to this conclusion, nor do I know if Obsidian indeed is the script writer and orchestrator of Sandy Hoax. But this is what I found out about Obsidian.
Obsidian Analysis Inc.
- ranks #217 in the 2014 Inc. 500 listing
- 5th-fastest growing private company in the District of Columbia
- Although Obsidian Analysis Inc. is among the Inc. 500, curiously Wikipedia does not have an entry on this company.
Meaning of Obsidian
The dictionary says the word "obsidian" has only one meaning. It is a noun for a hard, dark (black or blackish green in color), opaque, glasslike volcanic rock formed by the rapid solidification of lava without crystallization.
Note the black pyramidal shape in place of the letter A.
Here's a picture on Obsidian's website making clear its corporate symbol is a black pyramid. The pyramid has occult Illuminati associations.
Just as I was thinking that what's missing in the pyramid is the single eye — also an Illuminati Masonic symbol — here's the eye! Obsidian Analysis Inc. is located on Eye St. in D.C.! You can't make this stuff up.
1776 Eye St NW 4th Floor | Washington DC 20006 | p: 202.459.0500 | email@example.com
I've been to Washington, D.C., at least 5 times, but I don't recall there being an Eye St. So I searched for "1776 Eye St. NW, Washington DC 20006" on Google Map, and just I had suspected, there is no Eye St., but there is an I St.
Here's a screenshot I took from Google Map (note Obsidian's proximity to the White House, a mere 2 blocks away!):
Now ask yourself this question:
Why would Obsidian Analysis Inc. present its address on its website as 1776 Eye St., instead of 1776 I St.?
What is Obsidian Analysis Inc.?
Obisdian says its clients are government (U.S.) and private sector. Obsidian describes itself as:
Obsidian Analysis provides superior management consulting services to decision makers across the full range of security and resilience domains. Our capabilities cover the entire life-cycle of decision making – from analysis and assessment; to planning; to course of action development; to incident operations; to evaluation; to training and exercising; as well as to stakeholder outreach and engagement.
This is interesting — "Exercise, Training, and Education":
Obsidian Analysis provides expert, professional, and relevant exercises, training, and education to clients in both the government and the private sector. Obsidian supports and develops high-impact crisis simulations and exercises across a variety of security and resilience challenges: including Cybersecurity, natural hazards, terrorist attacks, as well; as climate adaptation. Obsidian applies a rigorous methodology to help organizations test plans, evaluate capabilities, and assess relationships among key partners and stakeholders. Obsidian has developed, executed, and evaluated 155 crisis simulations and exercises from the local level through the Federal Cabinet, including the President of the United States.
Obsidian Analysis plans, directs, and coordinates Training and Education programs that enhance the knowledge and skills of our clients' workforces. By rigorously assessing training and education needs, Obsidian training and education programs focus resources on building the most relevant and mission-critical knowledge and skills.
Obsidian's Leadership Team
Many of what Obsidian calls its "leadership team" of 20 (16 men, 4 women) formerly worked for BAE Systems (formerly Detica and DFI Government Services) and/or some agency of the federal government, typically DHS, NSA, or FEMA. Below are the 3 top leaders.
Note: BAE Systems is a British multinational defense, security and aerospace company headquartered in London, with operations worldwide. It is among the world's largest defense contractors — the second-largest based on applicable 2012 revenues.Its largest operations are in the United Kingdom and United States, where its BAE Systems Inc. subsidiary is one of the six largest suppliers to the US Department of Defense.
1. Kevin P. O'Prey, Ph.D.: Co-founder, chairman & president of Obsidian. Ph.D. in Political Science from the Massachusetts Institute of Technology; B.A. in International Relations from Grinnell College. Author of several books on international security; formerly a fellow at the Brookings Institution, Managing Partner of the Palisades Group, and President of DFI Government Services.
2. Matthew Travis: Co-founder and executive VP of Obsidian. Former president of Detica, Inc. (formerly DFI International). A former naval officer, Mr. Travis served as engineering officer aboard USS CARR (FFG 52) and as White House Liaison to the Secretary of the Navy. A graduate of the University of Notre Dame, Mr. Travis also earned a Master's Degree in National Security Studies from Georgetown University and an Executive Education Certificate from Harvard Business School.
3. Jason McNamara: VP of Obsidian. Former chief-of-staff of FEMA. B.A. in Sociology and Psychology from Johns Hopkins University; M.A. in Urban Affairs and Public Policy from University of Delaware.
For all the posts FOTM has published on Sandy Hoax, go to our "Sandy Hook Massacre" page.


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sort by best latest
As a man, I feel every man should be tall and handsome, educated, brilliant and strong enough to face the world. The basic thing in a man should be caring his parents and family. He should be kind hearted at times and popular among the people due to his descency but should not be proudy. If he is a good son, brother or friend, he can lead the world and one day his life will be filled with happiness and when he becomes father,
his children would also have the same good qualities.
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The Duncan Trussell Family Hour
Krishna Das
Tuesday · March 21, 2017
Doors: 7:00 pm / Show: 8:00 pmThe Bell House
Tickets at the Door
This event is 21 and overhttps://www.thebellhouseny.com/event/1438188/
The Duncan Trussell Family Hour
Duncan Trussell
Duncan Trussell is a stand-up comedian and podcaster who most recently co-hosted Syfy channel's "Joe Rogan Questions Everything" and appeared on Comedy Central's "This is Not Happening". Duncan's popular podcast, "The Duncan Trussell Family Hour" (www.duncantrussell.com), is known for its blend of humor, fringe ideas, eclectic guests, and great interviews. He regularly tours the country as a stand-up comedian and has performed at Just for Laughs Festival in Montreal and the Moontower Comedy Festival in Austin. In addition, Duncan has appeared on "Curb Your Enthusiasm", "Nick Swardson's Pretend Time", Cartoon Network's "Adventure Time", and Funny or Die's "Drunk History".
Krishna Das
Krishna Das layers traditional Hindu kirtan with instantly accessible melodies and modern instrumentation. With a remarkably soulful voice that touches the deepest chord in even the most casual listener, Krishna Das – known to friends, family, and fans as simply KD – has taken the call-and-response chanting out of yoga centers and into concert halls, becoming a worldwide icon and the best-selling chant artist of all time.
Learn more at www.krishnadas.com.
Learn more at www.krishnadas.com.
Venue Information:
The Bell House
149 7th Street
Brooklyn, New York, 11215
The Bell House
149 7th Street
Brooklyn, New York, 11215


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SAN FRANCISCO -- The San Francisco Giants trail the Los Angeles Dodgers in the N.L. West by a 12 game. In 2010, they entered the break trailing by two games and went 45-29 en route to a World Series title. In 2011, they entered the break leading the division by three games, went 34-36 and missed the playoffs.
Are there positives to glean from the past about running just behind the pace horse?
"You know what, there could be," first baseman Brandon Belt said. "It might give you that fire that says you've gotta step it up in the second half.
"Maybe it adds a little more intensity, maybe it adds a little more fun."
Fun is something the Giants know, and the vibe in the clubhouse Friday as players returned from the All-Star break was that of old friends reuniting -- showing off sunburns and vacation images captured on smart phones.
"I was missing them already, man, after three days!" Angel Pagan said. "That's something that's pretty cool. That you look forward to get back with your teammates and go to war."
Bochy noticed it too.
"The break is nice, and we had some guys that needed it, but it's good to get back. After a couple days, you're excited to get back, can't wait to get back.
"We're like a family."
The Giants, who have dropped seven of their last nine games entering the break, will need to come together as a family and turn things around for a second-half push. The Diamondbacks took a three-game winning streak into the break and 2011 N.L. MVP runner-up Matt Kemp is back in the Dodgers lineup after missing 51 games in the first half.
Do the Giants have enough in the clubhouse to win the West? Friday's starter Madison Bumgarner tackled the question on Chronicle Live Thursday.
"I think so," Bumgarner said. "If we didn't think so, that'd be our first problem."
The team support started early Friday with Pablo Sandoval, Angel Pagan and Nate Schierholtz taking batting practice in front of an empty stadium in shorts, working on their swings together.
"It's something that feels really good," Pagan said. "When you have teammates that look out for each other. When someone struggles, somebody's got your back. There's no better feeling than that, and that's the type of clubhouse we have."