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Items where Division is "05 Faculty of Science > Departement Pharmazeutische Wissenschaften > Pharmazie > Molecular and Systems Toxicology (Odermatt)"
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Number of items at this level: 104.
Araya, Selene and Kratschmar, Denise V. and Tsachaki, Maria and Stücheli, Simon and Beck, Katharina R. and Odermatt, Alex. (2017) DHRS7 (SDR34C1) - A new player in the regulation of androgen receptor function by inactivation of 5α-dihydrotestosterone? Journal of Steroid Biochemistry and Molecular Biology, 27. pp. 288-295.
Beck, Katharina R. and Bächler, Murielle and Vuorinen, Anna and Wagner, Sandra and Akram, Muhammad and Griesser, Ulrich and Temml, Veronika and Klusonova, Petra and Yamaguchi, Hideaki and Schuster, Daniela and Odermatt, Alex. (2017) Inhibition of 11β-hydroxysteroid dehydrogenase 2 by the fungicides itraconazole and posaconazole. Biochemical pharmacology, 130. pp. 93-103.
Beck, Katharina R. and Kaserer, Teresa and Schuster, Daniela and Odermatt, Alex. (2017) Virtual screening applications in short-chain dehydrogenase/reductase research. Journal of Steroid Biochemistry and Molecular Biology, 171. pp. 157-177.
Ben Rhouma, Bochra and Kallabi, Fakhri and Mahfoudh, Nadia and Ben Mahmoud, Afif and Engeli, Roger T. and Kamoun, Hassen and Keskes, Leila and Odermatt, Alex and Belguith, Neila. (2017) Novel cases of Tunisian patients with mutations in the gene encoding 17β-hydroxysteroid dehydrogenase type 3 and a founder effect. Journal of Steroid Biochemistry and Molecular Biology, 165 (A). pp. 86-94.
Bonifacio, Annalisa and Sanvee, Gerda M. and Brecht, Karin and Kratschmar, Denise V. and Odermatt, Alex and Bouitbir, Jamal and Krähenbühl, Stephan. (2017) IGF-1 prevents simvastatin-induced myotoxicity in C2C12 myotubes. Archives of Toxicology, 91 (5). pp. 2223-2234.
Boudon, Stéphanie M. and Vuorinen, Anna and Geotti-Bianchini, Piero and Wandeler, Eliane and Kratschmar, Denise V. and Heidl, Marc and Campiche, Remo and Jackson, Eileen and Odermatt, Alex. (2017) Novel 11β-hydroxysteroid dehydrogenase 1 inhibitors reduce cortisol levels in keratinocytes and improve dermal collagen content in human ex vivo skin after exposure to cortisone and UV. PLoS One, 12 (2). e0171079.
Strajhar, Petra. The effects of xenobiotics on steroidogenesis in human: "in vitro" and "in vivo" investigations. 2017, PhD Thesis, University of Basel, Faculty of Science.
Strajhar, Petra and Tonoli, David and Jeanneret, Fabienne and Imhof, Raphaella M. and Malagnino, Vanessa and Patt, Melanie and Kratschmar, Denise V. and Boccard, Julien and Rudaz, Serge and Odermatt, Alex. (2017) Steroid profiling in H295R cells to identify chemicals potentially disrupting the production of adrenal steroids. Toxicology, 381. pp. 51-63.
Tsachaki, Maria and Meyer, Arne and Weger, Benjamin and Kratschmar, Denise V. and Tokarz, Janina and Adamski, Jerzy and Belting, Heinz-Georg and Affolter, Markus and Dickmeis, Thomas and Odermatt, Alex. (2017) Absence of 11-keto reduction of cortisone and 11-ketotestosterone in the model organism zebrafish. Journal of Endocrinology, 232 (2). pp. 323-335.
May 2016
Canonica, Jérémie and Sergi, Chloé and Maillard, Marc and Klusonova, Petra and Odermatt, Alex and Koesters, Robert and Loffing-Cueni, Dominique and Loffing, Johannes and Rossier, Bernard and Frateschi, Simona and Hummler, Edith. (2016) Adult nephron-specific MR-deficient mice develop a severe renal PHA-1 phenotype. Pflügers Archiv : European journal of physiology, 468 (5). pp. 895-908.
Mani, Orlando and Nashev, Lyubomir G. and Livelo, Christopher and Baker, Michael E. and Odermatt, Alex. (2016) Role of Pro-637 and Gln-642 in human glucocorticoid receptors and Ser-843 and Leu-848 in mineralocorticoid receptors in their differential responses to cortisol and aldosterone. The Journal of steroid biochemistry and molecular biology, 159. pp. 31-40.
April 2016
Odermatt, Alex and Strajhar, Petra and Engeli, Roger T.. (2016) Disruption of steroidogenesis: Cell models for mechanistic investigations and as screening tools. The Journal of steroid biochemistry and molecular biology, 158. pp. 9-21.
Ramming, Thomas and Kanemura, Shingo and Okumura, Masaki and Inaba, Kenji and Appenzeller-Herzog, Christian. (2016) Cysteines 208 and 241 in Ero1α are required for maximal catalytic turnover. Redox biology, 7. pp. 14-20.
March 2016
Strajhar, Petra and Schmid, Y. and Liakoni, E. and Dolder, P. C. and Rentsch, K. M. and Kratschmar, Denise V. and Odermatt, Alex and Liechti, Matthias E.. (2016) Acute Effects of Lysergic Acid Diethylamide on Circulating Steroid Levels in Healthy Subjects. Journal of neuroendocrinology, 28 (3). p. 12374.
February 2016
Rizner, Tea Lanisnik and Sasano, Hironobu and Choi, Man Ho and Odermatt, Alex and Adamski, Jerzy. (2016) Recommendations for description and validation for antibodies for research use. The journal of steroid biochemistry and molecular biology, 156. pp. 40-42.
January 2016
Engeli, Roger T. and Rhouma, Bochra Ben and Sager, Christoph P. and Tsachaki, Maria and Birk, Julia and Fakhfakh, Faiza and Keskes, Leila and Belguith, Neila and Odermatt, Alex. (2016) Biochemical analyses and molecular modeling explain the functional loss of 17β-hydroxysteroid dehydrogenase 3 mutant G133R in three Tunisian patients with 46, XY Disorders of Sex Development. The Journal of steroid biochemistry and molecular biology, 155. pp. 147-154.
Beck, Katharina R. and Sommer, Tanja J. and Schuster, Daniela and Odermatt, Alex. (2016) Evaluation of tetrabromobisphenol A effects on human glucocorticoid and androgen receptors: A comparison of results from human- with yeast-based in vitro assays. Toxicology, 370. pp. 70-77.
Dubost, Valérie. Assessment of podocyte injury using two novel glomerular markers. 2016, PhD Thesis, University of Basel, Faculty of Science.
December 2015
Kaserer, Teresa and Beck, Katharina and Akram, Muhamad and Odermatt, Alex and Schuster, Daniela. (2015) Pharmacophore models and pharmacophore-based virtual screening: concepts and applications exemplified on hydroxysteroid dehydrogenases. Molecules, 20 (12). pp. 22799-22832.
Shelton, Luke M. and Lister, Adam and Walsh, Joanne and Jenkins, Rosalind E. and Wong, Michael H. L. and Rowe, Cliff and Ricci, Emanuele and Ressel, Lorenzo and Fang, Yongxiang and Demougin, Philippe and Vukojevic, Vanja and O'Neill, Paul M. and Goldring, Christopher E. and Kitteringham, Neil R. and Park, B. Kevin and Odermatt, Alex and Copple, Ian M.. (2015) Integrated transcriptomic and proteomic analyses uncover regulatory roles of Nrf2 in the kidney. Kidney international, 88 (6). pp. 1261-1273.
1 November 2015
Di Chiara, Marianna and Glaudemans, Bob and Loffing-Cueni, Dominique and Odermatt, Alex and Al-Hasani, Hadi and Devuyst, Olivier and Faresse, Nourdine and Loffing, Johannes. (2015) Rab-GAP TBC1D4 (AS160) is dispensable for the renal control of sodium and water homeostasis but regulates GLUT4 in mouse kidney. American journal of physiology. Gastrointestinal and liver physiology, 309 (9). F779-F790.
November 2015
Seibert, Julia K. and Quagliata, Luca and Quintavalle, Cristina and Hammond, Thomas G. and Terracciano, Luigi and Odermatt, Alex. (2015) A role for the dehydrogenase DHRS7 (SDR34C1) in prostate cancer. Cancer medicine, 4 (11). pp. 1717-1729.
July 2015
Odermatt, Alex and Klusonova, Petra. (2015) 11β-Hydroxysteroid dehydrogenase 1: Regeneration of active glucocorticoids is only part of the story. The journal of steroid biochemistry and molecular biology, 151. pp. 85-92.
Tsachaki, Maria and Birk, Julia and Egert, Aurélie and Odermatt, Alex. (2015) Determination of the topology of endoplasmic reticulum membrane proteins using redox-sensitive green-fluorescence protein fusions. Biochimica et biophysica acta. Molecular cell research, 1853 (7). pp. 1672-1682.
June 2015
Delaunay-Moisan, Agnès and Appenzeller-Herzog, Christian. (2015) The antioxidant machinery of the endoplasmic reticulum: Protection and signaling. Free radical biology & medicine, 83. pp. 341-351.
Ramming, Thomas and Okumura, Masaki and Kanemura, Shingo and Baday, Sefer and Birk, Julia and Moes, Suzette and Spiess, Martin and Jenö, Paul and Bernèche, Simon and Inaba, Kenji and Appenzeller-Herzog, Christian. (2015) A PDI-catalyzed thiol-disulfide switch regulates the production of hydrogen peroxide by human Ero1. Free radical biology & medicine, 83. pp. 361-372.
May 2015
Tonoli, David and Fürstenberger, Cornelia and Boccard, Julien and Hochstrasser, Denis and Jeanneret, Fabienne and Odermatt, Alex and Rudaz, Serge. (2015) Steroidomic Footprinting Based on Ultra-High Performance Liquid Chromatography Coupled with Qualitative and Quantitative High-Resolution Mass Spectrometry for the Evaluation of Endocrine Disrupting Chemicals in H295R Cells. Chemical research in toxicology, 28 (5). pp. 955-966.
April 2015
Vuorinen, Anna and Seibert, Julia and Papageorgiou, Vassilios P. and Rollinger, Judith M. and Odermatt, Alex and Schuster, Daniela and Assimopoulou, Andreana N.. (2015) Pistacia lentiscus Oleoresin: Virtual Screening and Identification of Masticadienonic and Isomasticadienonic Acids as Inhibitors of 11β-Hydroxysteroid Dehydrogenase 1. Planta medica, 81 (6). pp. 525-532.
Seibert, Julia Katharina. Characterization of the 11β-hydroxysteroid dehydrogenase 1-related short-chain dehydrogenase/reductase DHRS7. 2015, PhD Thesis, University of Basel, Faculty of Science.
Vuorinen, Anna and Odermatt, Alex and Schuster, Daniela. (2015) Reprint of "In silico methods in the discovery of endocrine disrupting chemicals". The Journal of steroid biochemistry and molecular biology, 153 (September 2015). pp. 93-101.
Blüthgen, Nancy. Effects of UV filters (benzophenones and octocrylene) and mifepristone on different life stages of zebrafish (Danio rerio). 2014, PhD Thesis, University of Basel, Faculty of Science.
Chantong, Boonrat. Regulation of microglial cell function by corticosteroids and disruption by organotins. 2014, PhD Thesis, University of Basel, Faculty of Science.
Chantong, Boonrat and Kratschmar, Denise V. and Lister, Adam and Odermatt, Alex. (2014) Dibutyltin promotes oxidative stress and increases inflammatory mediators in BV-2 microglia cells. Toxicology letters, Vol. 230, H. 2. S. 177-187.
Chantong, Boonrat and Kratschmar, Denise V. and Lister, Adam and Odermatt, Alex. (2014) Inhibition of metabotropic glutamate receptor 5 induces cellular stress through pertussis toxin-sensitive G i -proteins in murine BV-2 microglia cells. Journal of neuroinflammation, Vol. 11, H. 1. S. 190.
Felser, Andrea and Lindinger, Peter W. and Schnell, Dominik and Kratschmar, Denise V. and Odermatt, Alex and Mies, Suzette and Jenö, Paul and Krähenbühl, Stephan. (2014) Hepatocellular toxicity of benzbromarone : Effects on mitochondrial function and structure. Toxicology, Vol. 324. S. 136-146.
Fürstenberger, Cornelia. Disruption of androgen metabolism, regulation and effects : involvement of steroidogenic enzymes. 2014, PhD Thesis, University of Basel, Faculty of Science.
Legeza, Balázs and Balázs, Zoltán and Odermatt, Alex. (2014) Fructose promotes the differentiation of 3T3-L1 adipocytes and accelerates lipid metabolism. FEBS letters, Vol. 588, H. 3. S. 490-496.
Penno, Carlos A. and Morgan, Stuart A. and Rose, Adam J. and Herzig, Stephan and Lavery, Gareth G. and Odermatt, Alex. (2014) 11β-Hydroxysteroid dehydrogenase-1 is involved in bile acid homeostasis by modulating fatty acid transport protein-5 in the liver of mice. Molecular metabolism, Vol. 3, H. 5. S. 554-564.
Ramming, Thomas and Hansen, Henning Gram and Nagata, Kazuhiro and Ellgaard, Lars and Appenzeller-Herzog, Christian. (2014) GPx8 peroxidase prevents leakage of H2O2 from the endoplasmic reticulum. Free radical biology & medicine, Vol. 70 , S. 106–116.
Seibert, Julia and Hysek, Cédric M. and Penno, Carlos A. and Schmid, Yasmin and Kratschmar, Denise V. and Liechti, Matthias E. and Odermatt, Alex. (2014) Acute Effects of 3,4-Methylenedioxymethamphetamine and Methylphenidate on Circulating Steroid Levels in Healthy Subjects. Neuroendocrinology, 100 (1). pp. 17-25.
Vuorinen, Anna and Engeli, Roger and Meyer, Arne and Bachmann, Fabio and Griesser, Ulrich J. and Schuster, Daniela and Odermatt, Alex. (2014) Ligand-based pharmacophore modeling and virtual screening for the discovery of novel 17β-hydroxysteroid dehydrogenase 2 inhibitors. Journal of medicinal chemistry, Vol. 57, H. 14. S. 5995-6007.
Appenzeller-Herzog, Christian and Birk, Julia. (2013) Erratum: Green fluorescent protein-based monitoring of endoplasmic reticulum redox poise. Frontiers in genetics, Vol. 4, art. 255 , 1 S..
Birk, Julia and Meyer, Mariangela and Aller, Isabel and Hansen, Henning G. and Odermatt, Alex and Dick, Tobias P. and Meyer, Andreas J. and Appenzeller-Herzog, Christian. (2013) Endoplasmic reticulum : reduced and oxidized glutathione revisited. Journal of Cell Science, 126 (7). pp. 1604-1617.
Birk, Julia and Ramming, Thomas and Odermatt, Alex and Appenzeller-Herzog, Christian. (2013) Green fluorescent protein-based monitoring of endoplasmic reticulum redox poise. Frontiers in genetics, Vol. 4, art. 108 , 10 S.. S. 108.
Boudon, Stéphanie. Characterization of phototoxicity reactions in human and animal skin models. 2013, PhD Thesis, University of Basel, Faculty of Science.
Legeza, Balazs. Generation and utilization of NADPH in the endoplasmic reticulum : novel insight into the role of luminal NADPH in pathophysiological processes. 2013, PhD Thesis, University of Basel, Faculty of Science.
Legeza, Balázs and Balázs, Zoltán and Nashev, Lyubomir G. and Odermatt, Alex. (2013) The microsomal enzyme 17β-hydroxysteroid dehydrogenase 3 faces the cytoplasm and uses NADPH generated by glucose-6-phosphate dehydrogenase. Endocrinology, Vol. 154, H. 1. S. 205-213.
Marchais-Oberwinkler, Sandrine and Xu, Kuiying and Wetzel, Marie and Perspicace, Enrico and Negri, Matthias and Meyer, Arne and Odermatt, Alex and Möller, Gabriele and Adamski, Jerzy and Hartmann, Rolf W.. (2013) Structural Optimization of 2,5-Thiophene Amides as Highly Potent and Selective 17β-Hydroxysteroid Dehydrogenase Type 2 Inhibitors for the Treatment of Osteoporosis. Journal of Medicinal Chemistry, Vol. 56, H. 1. S. 167-181.
Meyer, Arne. The role of the endoplasmic reticulum in the metabolism of "xenobiotica". 2013, PhD Thesis, University of Basel, Faculty of Science.
Meyer, Arne and Vuorinen, Anna and Zielinska, Agnieszka E. and Da Cunha, Thierry and Strajhar, Petra and Lavery, Gareth G. and Schuster, Daniela and Odermatt, Alex. (2013) Carbonyl reduction of triadimefon by human and rodent 11β-hydroxysteroid dehydrogenase 1. Biochemical pharmacology, Vol. 85, H. 9. S. 1370-1378.
Meyer, Arne and Vuorinen, Anna and Zielinska, Agnieszka E. and Strajhar, Petra and Lavery, Gareth G. and Schuster, Daniela and Odermatt, Alex. (2013) Formation of threohydrobupropion from bupropion is dependent on 11β-hydroxysteroid dehydrogenase 1. Drug metabolism and disposition, Vol. 41, H. 9. S. 1671-1678.
Montero, Davide and Tachibana, Christine and Rahr Winther, Jakob and Appenzeller-Herzog, Christian. (2013) Intracellular glutathione pools are heterogeneously concentrated. Redox biology, Vol. 1, H. 1. S. 508-513.
Nashev, Lyubomir G. and Atanasov, Atanas G. and Baker, Michael E. and Odermatt, Alex. (2013) Cysteine-10 on 17 β-Hydroxysteroid dehydrogenase 1 has stabilizing interactions in the cofactor binding region and renders sensitivity to sulfhydryl modifying chemicals. International journal of cell biology, Vol. 2013 , art. 769536.
Pandya, Keyur and Dietrich, David and Seibert, Julia and Vederas, John C. and Odermatt, Alex. (2013) Synthesis of sterically encumbered 11β-aminoprogesterone derivatives and evaluation as 11β-hydroxysteroid dehydrogenase inhibitors and mineralocorticoid receptor antagonists. Bioorganic & medicinal chemistry letters, Vol. 21, H. 21. S. 6274-6281.
Penno, C. A. and Arsenijevic, D: Da Cunha and Kullak-Ublick, G. A. and Montani, J.-P. and Odermatt, A.. (2013) Quantification of multiple bile acids in uninephrectomized rats using ultra-performance liquid chromatography-tandem mass spectrometry. Analytical methods, Vol. 5. S. 1155-1164.
Penno, Carlos A. and Morgan, Stuart A. and Vuorinen, Anna and Schuster, Daniela and Lavery, Gareth G. and Odermatt, Alex. (2013) Impaired oxidoreduction by 11β-hydroxysteroid dehydrogenase 1 results in the accumulation of 7-oxolithocholic acid. Journal of Lipid Research, 54 (10). pp. 2874-2883.
Penno, Carlos Alberto. The role of 11β-hydroxysteroid dehydrogenase type 1 in bile acid homeostasis. 2013, PhD Thesis, University of Basel, Faculty of Science.
Ramming, Thomas and Appenzeller-Herzog, Christian. (2013) Destroy and exploit: catalyzed removal of hydroperoxides from the endoplasmic reticulum. International journal of cell biology, Vol. 2013 , 180906.
Wright, Jordan and Birk, Julia and Haataja, Leena and Liu, Ming and Ramming, Thomas and Weiss, Michael A. and Appenzeller-Herzog, Christian and Arvan, Peter. (2013) Endoplasmic reticulum oxidoreductin-1α (Ero1α) improves folding and secretion of mutant proinsulin and limits mutant proinsulin-induced endoplasmic reticulum stress. Journal of biological chemistry, 288 (43). pp. 31010-31018.
Appenzeller-Herzog, Christian. (2012) Updates on "Endoplasmic Reticulum Redox". Antioxidants & redox signaling, Vol. 16, No. 8. S. 760-762.
Chantong, Boonrat and Kratschmar, Denise V. and Nashev, Lyubomir G. and Balazs, Zoltan and Odermatt, Alex. (2012) Mineralocorticoid and glucocorticoid receptors differentially regulate NF-kappaB activity and pro-inflammatory cytokine production in murine BV-2 microglial cells. Journal of neuroinflammation, Vol. 9. S. 260.
Fürstenberger, Cornelia and Vuorinen, Anna and Da Cunha, Thierry and Kratschmar, Denise V. and Saugy, Martial and Schuster, Daniela and Odermatt, Alex. (2012) The anabolic androgenic steroid fluoxymesterone inhibits 11β-hydroxysteroid dehydrogenase 2-dependent glucocorticoid inactivation. Toxicological sciences, Vol. 126, H. 2. S. 353-361.
Hansen, Henning Gram and Schmidt, Jonas Damgård and Søltoft, Cecilie Lützen and Ramming, Thomas and Geertz-Hansen, Henrik Marcus and Christensen, Brian and Sørensen, Esben Skipper and Juncker, Agnieszka Sierakowska and Appenzeller-Herzog, Christian and Ellgaard, Lars. (2012) Hyperactivity of the ero1α oxidase elicits endoplasmic reticulum stress but no broad antioxidant response. Journal of biological chemistry, Vol. 287, H. 47. S. 39513-39523.
Kratschmar, Denise V. and Calabrese, Diego and Walsh, Jo and Lister, Adam and Birk, Julia and Appenzeller-Herzog, Christian and Moulin, Pierre and Goldring, Chris E. and Odermatt, Alex. (2012) Suppression of the Nrf2-dependent antioxidant response by glucocorticoids and 11β-HSD1-mediated glucocorticoid activation in hepatic cells. PLoS one, Vol. 7, H. 5 , e36774.
Meyer, Arne and Strajhar, Petra and Murer, Céline and Da Cunha, Thierry and Odermatt, Alex. (2012) Species-specific differences in the inhibition of human and zebrafish 11β-hydroxysteroid dehydrogenase 2 by thiram and organotins. Toxicology, Vol. 301, H. 1-3. S. 72-78.
Nashev, Lyubomir G. and Vuorinen, Anna and Praxmarer, Lukas and Chantong, Boonrat and Cereghetti, Diego and Winiger, Rahel and Schuster, Daniela and Odermatt, Alex. (2012) Virtual screening as a strategy for the identification of xenobiotics disrupting corticosteroid action. PLoS one, Vol. 7, H. 10 , e46958.
Odermatt, Alex and Kratschmar, Denise V.. (2012) Tissue-specific modulation of mineralocorticoid receptor function by 11β-hydroxysteroid dehydrogenases : an overview. Molecular and cellular endocrinology, Vol. 350, H. 2. S. 168-186.
Ramming, Thomas and Appenzeller-Herzog, Christian. (2012) The physiological functions of mammalian endoplasmic oxidoreductin 1: on disulfides and more. Antioxidants & redox signaling, Vol. 16, No. 10. S. 1109-1118.
Vacchi-Suzzi, Caterina. MicroRNAs regulatory networks in cardiotoxicity. 2012, PhD Thesis, University of Basel, Faculty of Science.
Veyrat-Durebex, Christelle and Deblon, Nicolas and Caillon, Aurélie and Andrew, Ruth and Altirriba, Jordi and Odermatt, Alex and Rohner-Jeanrenaud, Françoise. (2012) Central glucocorticoid administration promotes weight gain and increased 11β-hydroxysteroid dehydrogenase type 1 expression in white adipose tissue. PLoS one, Vol. 7, H. 3 , e34002.
Appenzeller-Herzog, Christian. (2011) Glutathione- and non-glutathione-based oxidant control in the endoplasmic reticulum. Journal of cell science, Vol. 124, H. 6. S. 847-855.
Blumberg, Bruce and Iguchi, Taisen and Odermatt, Alex. (2011) Endocrine disrupting chemicals. The journal of steroid biochemistry and molecular biology, Vol. 127, H. 1/2. S. 1-3.
Gaware, Rawindra and Khunt, Rupesh and Czollner, Laszlo and Stanetty, Christian and Da Cunha, Thierry and Kratschmar, Denise V. and Odermatt, Alex and Kosma, Paul and Jordis, Ulrich and Classen-Houben, Dirk. (2011) Synthesis of new glycyrrhetinic acid derived ring A azepanone, 29-urea and 29-hydroxamic acid derivatives as selective 11?-hydroxysteroid dehydrogenase 2 inhibitors. Bioorganic & medicinal chemistry, Vol. 19, H. 6. S. 1866-1880.
Kratschmar, Denise V. and Vuorinen, Anna and Da Cunha, Thierry and Wolber, Gerhard and Classen-Houben, Dirk and Doblhoff, Otto and Schuster, Daniela and Odermatt, Alex. (2011) Characterization of activity and binding mode of glycyrrhetinic acid derivatives inhibiting 11?-hydroxysteroid dehydrogenase type 2. The journal of steroid biochemistry and molecular biology, Vol. 125, H. 1-2. S. 129-142.
Odermatt, Alex. (2011) The Western-style diet : a major risk factor for impaired kidney function and chronic kidney disease. American journal of physiology. Renal Physiology, Vol. 301, H. 5 , F919-931.
Odermatt, Alex and Da Cunha, Thierry and Penno, Carlos A. and Chandsawangbhuwana, Charlie and Reichert, Christian and Wolf, Armin and Dong, Min and Baker, Michael E.. (2011) Hepatic reduction of the secondary bile acid 7-oxolithocholic acid is mediated by 11?-hydroxysteroid dehydrogenase 1. The Biochemical Journal, Vol. 436, H. 3. S. 621-629.
Reichenbach, Stephan and Leunig, Michael and Werlen, Stefan and Nüesch, Eveline and Pfirrmann, Christian W. and Bonel, Harald and Odermatt, Alex and Hofstetter, Willy and Ganz, Reinhold and Jüni, Peter. (2011) Association between cam-type deformities and magnetic resonance imaging-detected structural hip damage : a cross-sectional study in young men. Arthritis and rheumatism, Vol. 63, H. 12. S. 4023-4030.
Schuster, Daniela and Kowalik, Dorota and Kirchmair, Johannes and Laggner, Christian and Markt, Patrick and Aebischer-Gumy, Christel and Ströhle, Fabian and Möller, Gabriele and Wolber, Gerhard and Wilckens, Thomas and Langer, Thierry and Odermatt, Alex and Adamski, Jerzy. (2011) Identification of chemically diverse, novel inhibitors of 17?-hydroxysteroid dehydrogenase type 3 and 5 by pharmacophore-based virtual screening. The journal of steroid biochemistry and molecular biology, Vol. 125, H. 1-2. S. 148-161.
Appenzeller-Herzog, Christian and Riemer, Jan and Zito, Ester and Chin, King-Tung and Ron, David and Spiess, Martin and Ellgaard, Lars. (2010) Disulphide production by Ero1alpha-PDI relay is rapid and effectively regulated. The EMBO journal, Vol. 29, H. 19. S. 3318-3329.
Beseda, Igor and Czollner, Laszlo and Shah, Priti S. and Khunt, Rupesh and Gaware, Rawindra and Kosma, Paul and Stanetty, Christian and Del Ruiz-Ruiz, Maria Carmen and Amer, Hassan and Mereiter, Kurt and Da Cunha, Thierry and Odermatt, Alex and Classen-Houben, Dirk and Jordis, Ulrich. (2010) Synthesis of glycyrrhetinic acid derivatives for the treatment of metabolic diseases. Bioorganic & medicinal chemistry, Vol. 18, H. 1. S. 433-454.
Nashev, Lyubomir G. and Schuster, Daniela and Laggner, Christian and Sodha, Seloni and Langer, Thierry and Wolber, Gerhard and Odermatt, Alex. (2010) The UV-filter benzophenone-1 inhibits 17beta-hydroxysteroid dehydrogenase type 3 : virtual screening as a strategy to identify potential endocrine disrupting chemicals. Biochemical Pharmacology, Vol. 79, Issue 8. S. 1189-1199.
Odermatt, Alex and Nashev, Lyubomir G.. (2010) The glucocorticoid-activating enzyme 11beta-hydroxysteroid dehydrogenase type 1 has broad substrate specificity: Physiological and toxicological considerations. The journal of steroid biochemistry and molecular biology, Vol. 119, H. 1-2. S. 1-13.
Reichenbach, Stephan and Jüni, Peter and Werlen, Stefan and Nüesch, Eveline and Pfirrmann, Christian W. and Trelle, Sven and Odermatt, Alex and Hofstetter, Willy and Ganz, Reinhold and Leunig, Michael. (2010) Prevalence of cam-type deformity on hip magnetic resonance imaging in young males : a cross-sectional study. Arthritis care & research, Vol. 62, H. 9. S. 1319-1327.
Rollinger, Judith M. and Kratschmar, Denise V. and Schuster, Daniela and Pfisterer, Petra H. and Gumy, Christel and Aubry, Evelyne M. and Brandstötter, Sarah and Stuppner, Hermann and Wolber, Gerhard and Odermatt, Alex. (2010) 11beta-Hydroxysteroid dehydrogenase 1 inhibiting constituents from Eriobotrya japonica revealed by bioactivity-guided isolation and computational approaches. Bioorganic & medicinal chemistry, Vol. 18, H. 4. S. 1507-1515.
Senesi, Silvia and Legeza, Balázs and Balázs, Zoltán and Csala, Miklós and Marcolongo, Paola and Kereszturi, Eva and Szelényi, Péter and Egger, Christine and Fulceri, Rosella and Mandl, József and Giunti, Roberta and Odermatt, Alex and Bánhegyi, Gábor and Benedetti, Angelo. (2010) Contribution of fructose-6-phosphate to glucocorticoid activation in the endoplasmic reticulum : possible implication in the metabolic syndrome. Endocrinology, Vol. 151, H. 10. S. 4830-4839.
Stanetty, Christian and Czollner, Laszlo and Koller, Iris and Shah, Priti and Gaware, Rawindra and Cunha, Thierry Da and Odermatt, Alex and Jordis, Ulrich and Kosma, Paul and Classen-Houben, Dirk. (2010) Synthesis of novel 3-amino and 29-hydroxamic acid derivatives of glycyrrhetinic acid as selective 11?-hydroxysteroid dehydrogenase 2 inhibitors. Bioorganic & medicinal chemistry, Vol. 18, H. 21. S. 7522-7541.
Aubry, E. M. and Odermatt, A.. (2009) Retinoic acid reduces glucocorticoid sensitivity in C2C12 myotubes by decreasing 11beta-hydroxysteroid dehydrogenase type 1 and glucocorticoid receptor activities. Endocrinology, Vol. 150, No. 6. S. 2700-2708.
Balazs, Z. and Nashev, L. G. and Chandsawangbhuwana, C. and Baker, M. E. and Odermatt, A.. (2009) Hexose-6-phosphate dehydrogenase modulates the effect of inhibitors and alternative substrates of 11beta-hydroxysteroid dehydrogenase 1. Molecular and cellular endocrinology, Vol. 301, H. 1-2. S. 117-122.
Classen-Houben, D. and Schuster, D. and Da Cunha, T. and Odermatt, A. and Wolber, G. and Jordis, U. and Kueenburg, B.. (2009) Selective inhibition of 11beta-hydroxysteroid dehydrogenase 1 by 18alpha-glycyrrhetinic acid but not 18beta-glycyrrhetinic acid. The journal of steroid biochemistry and molecular biology, Vol. 113, H. 3-5. S. 248-252.
Dzyakanchuk, A. A. and Balazs, Z. and Nashev, L. G. and Amrein, K. E. and Odermatt, A.. (2009) 11beta-Hydroxysteroid dehydrogenase 1 reductase activity is dependent on a high ratio of NADPH/NADP(+) and is stimulated by extracellular glucose. Molecular and cellular endocrinology, Vol. 301, H. 1-2. S. 137-141.
Gumy, C. and Thurnbichler, C. and Aubry, E. M. and Balazs, Z. and Pfisterer, P. and Baumgartner, L. and Stuppner, H. and Odermatt, A. and Rollinger, J. M.. (2009) Inhibition of 11beta-hydroxysteroid dehydrogenase type 1 by plant extracts used as traditional antidiabetic medicines. Fitoterapia, Vol. 80, no.3. S. 200-205.
Odermatt, A.. (2009) Diazepane-acetamide derivatives as selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitors. Expert opinion on therapeutic patents, Vol. 19, H. 10. S. 1477-1483.
Odermatt, A. and Atanasov, A. G.. (2009) Mineralocorticoid receptors : Emerging complexity and functional diversity. Steroids, Vol. 74, H. 2. S. 163-171.
Riemer, Jan and Appenzeller-Herzog, Christian and Johansson, Linda and Bodenmiller, Bernd and Hartmann-Petersen, Rasmus and Ellgaard, Lars. (2009) A luminal flavoprotein in endoplasmic reticulum-associated degradation. Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, H. 35. S. 14831-14836.
Atanasov, Atanas G. and Nashev, Lyubomir G. and Gelman, Laurent and Legeza, Balazs and Sack, Ragna and Portmann, Reto and Odermatt, Alex. (2008) Direct protein-protein interaction of 11 beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase in the endoplasmic reticulum lumen. Biochimica et biophysica acta. Molecular cell research, Vol. 1783, Issue 8. S. 1536-1543.
Balazs, Z. and Schweizer, R. A. and Frey, F. J. and Rohner-Jeanrenaud, F. and Odermatt, A.. (2008) DHEA induces 11beta-HSD2 by acting on CCAAT/enhancer-binding proteins. Journal of the American Society of Nephrology, Vol. 19, H. 1. S. 92-101.
Gumy, C. and Chandsawangbhuwana, C. and Dzyakanchuk, A. A. and Kratschmar, D. V. and Baker, M. E. and Odermatt, A.. (2008) Dibutyltin disrupts glucocorticoid receptor function and impairs glucocorticoid-induced suppression of cytokine production. PLoS one, Vol. 3, H. 10 , e3545.
Kardon, Tamás and Senesi, Silvia and Marcolongo, Paola and Legeza, Balázs and Bánhegyi, Gábor and Mandl, József and Fulceri, Rosella and Benedetti, Angelo. (2008) Maintenance of luminal NADPH in the endoplasmic reticulum promotes the survival of human neutrophil granulocytes. FEBS letters, Vol. 582, H. 13. S. 1809-1815.
Odermatt, Alex and Gumy, Christel. (2008) Disruption of glucocorticoid and mineralocorticoid receptor-mediated responses by environmental chemicals. Chimia, 62 (5). pp. 335-339.
Odermatt, Alex and Gumy, Christel. (2008) Glucocorticoid and mineralocorticoid action : Why should we consider influences by environmental chemicals? Biochemical Pharmacology, Volume 76, Issue 10. S. 1184-1193.
Schuster, Daniela and Nashev, Lyubomir G. and Kirchmair, Johannes and Laggner, Christian and Wolber, Gerhard and Langer, Thierry and Odermatt, Alex. (2008) Discovery of nonsteroidal 17 beta-hydroxysteroid dehydrogenase 1 inhibitors by pharmacophore-based screening of virtual compound libraries. Journal of medicinal chemistry, Vol. 51, no. 14. S. 4188-4199.
Atanasov, A. G. and Ignatova, I. D. and Nashev, L. G. and Dick, B. and Ferrari, P. and Frey, F. J. and Odermatt, A.. (2007) Impaired protein stability of 11beta-hydroxysteroid dehydrogenase type : a novel mechanism of apparent mineralocorticoid excess. Journal of the American Society of Nephrology, Vol. 18, H. 4. S. 1262-1270.
Nashev, L. G. and Chandsawangbhuwana, C. and Balazs, Z. and Atanasov, A. G. and Dick, B. and Frey, F. J. and Baker, M. E. and Odermatt, A.. (2007) Hexose-6-phosphate Dehydrogenase Modulates 11beta-Hydroxysteroid Dehydrogenase Type 1-Dependent Metabolism of 7-keto- and 7beta-hydroxy-neurosteroids. PLoS one, Vol. 2, H. 6 , e561.
Appenzeller-Herzog, C. and Nyfeler, B. and Burkhard, P. and Santamaria, I. and Lopez-Otin, C. and Hauri, H. -P.. (2005) Carbohydrate- and conformation-dependent cargo capture for ER-exit. Molecular Biology of the Cell, 16 (3). pp. 1258-1267.


text:
- Please select a date to see the proper prices!
Description of the accommodation:
Rooms, services Hotel one66 St. Gallen is pleased to host travellers looking to spend a few pleasant days in Switzerland. The guests of the hotel may stay in 83 nicely furnished, comfortable rooms in St. Gallen. Car parking possibility is available nearby. The bar has excellent atmosphere for a relaxed evening talk or a personal meeting. You may secure your valuables in the safe. Wireless Internet connection (WiFi) is available at the hotel, ensuring that you can stay up-to-date during your holiday. You can find the exact list of services provided by Hotel one66 St. Gallen (including those for extra fees) and the exact equipment of the rooms on the information sheet below.
Payment Depeding on the selected room, date and price, you may be asked to provide credit card guarantee or to pay by credit card in advance.
Arrival, opening hours The earliest check-in time to your room is 14:00, the latest check-out time from your room is 11:00. The personnel can speak English and German languages.
Hotel one66 St. Gallen rooms Rooms
- Please select a date to see the proper prices!
Accommodation services
Free WiFi in shared places
Pet friendly (10 €/night), Bar, Elevator, Safe deposit box
Hairdryer, Desk in the room

subset: commoncrawl


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It was so easy to snap at my father that night.
We had just finished a big dinner. He said something about politics that I didn't like. I shot out like a cannon at him. No thinking, no effort. Just a big boom of righteous indignation.
And it was so easy to do because I'd done it before. I'd spent years making that snapping impulse good and strong. Yet never once had it left me, the moment, or some greater purpose better off.
A few days later, I was washing dishes. And I had the idea to text a friend to let her know I loved her. No, I thought, your hands are soapy. It's not that important. Do it later.
In plain English: it was too much effort.
And my mind began working over that. The snapping impulse was primed and ready; the kindness impulse was a little harder to reach. Is that how you want the scales to be set?
I dried my hands. I texted my love to that friend. I went back to the dishes. And I felt softer, more connected.
Okay, I thought, that's one step towards strengthening the kindness impulse. Keep on taking those.
So if I feel a surge of love, I've resolved to act on it. Immediately. Speak it. Text, call, write it.
And each time I think it's too much effort, I tell myself that all I'm doing is making that kindness impulse good and strong. So it requires no thinking, no effort. But just shoots out like a cannon.


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You'll contact Indium. We'll set a time to chat. We'll talk about your story, what look you're envisioning, wardrobe ideas, and schedule your photoshoot time and date. In-person consultations are optional and done at my studio.
You'll arrive to my studio super excited. We'll start with hair and makeup & then begin the epic photoshoot with the fan blowing your hair, listening to your fav tunes. The whole day is dedicated to you so there's no feeling rushed!
After the shoot is wrapped up, you'll go grab a bite to eat. Make your S.O. or a friend meet up because you'll look gorgeous. Come back one hour later to see how pretty your final photos turned out! You'll pick out your favs and place your order. Everything will be ready 2-4 weeks later.
With Indium Boudoir, you'll get the full model-for-a-day experience by getting your hair and makeup done with Kansas City's best artist. This is included with every session!
With Indium Boudoir, you'll get the full model-for-a-day experience by getting your hair and makeup done with Kansas City's best artist. This is included with every session!
So you've got some concerns, right? There are a lot of excuses: "I want to lose weight. I'm too scared. I'm not sexy. I'm going to look silly. I don't know how to pose." None of that is true.
I will be there to guide you through the entire shoot, giving you direction down to where your hands, eyes, chin, shoulders, and legs need to be. I've been shooting since '07 and know exactly how to pose you for the most flattering angles. I see the beauty in every woman I photograph.
If you are saying "maybe later", do it now because sometimes later becomes never. If you're not at your ideal weight, make it a challenge. Schedule your boudoir shoot 1-3 months in advance and make it your goal to lose your "xx lbs" by then. Boom. Solved.
Yes, your S.O. will love these photos (duh), but it will do far more good for you. You will leave feeling liberated, empowered, and gorgeous. You'll want to show off your photos to all your closest friends. You'll be thinking, "I can't believe that's me!"
I promise that you are going to look absolutely stunning in these photos so email me right now to schedule your consultation because when was the last time you had a beautiful portrait taken? You deserve to have beautiful photographs of yourself. This is a life changing experience in the best way possible.


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Ventnor, NJ (PressExposure) August 03, 2012 -- Following more than five years as pure instrumentalists, Jersey progressive-rock band Eternal Essence releases their first LP featuring lead vocals, "A Light in the Distance." With guitars that sometimes tear and sometimes caress, bass like a bulletproof suspension bridge, drums that cruise, groove, and kick holes in walls, and a vocalist that soars above the ocean of sound like a bird on the wing, Eternal Essence steps into the rock foreground as if to say, "Oh, that? Yeah, we've been that awesome for awhile now. Sorry to startle you." It would seem that all of a sudden, the East Coast indie scene has an obscene amount of awesome to live up to.
Eternal Essence bills themselves as progressive rock in the vein of Dream Theater, Rush, and Pink Floyd. All the best qualities of these powerhouse bands are indeed present in their music. However, fans of hardcore music will immediately identify them with the high-octane sounds of the infant emo scene of the early nineteen-nineties, when east coast bands like Quicksand, and west coast groups like Farside (Revelation Records) were forsaking the insipid, sappy whining of grunge performers to make music that was heavy-hitting and honest, free of music-industry pretentiousness. Eternal Essence is a return to everything that was ever good about punk rock, all the expertise of heavy metal instrumentation, and the exacting values of painstakingly premeditated songwriting. In a word, E.E. is exactly what modern music has, literally, been dying without.
Not unlike the Washington D.C. band Ashes, they've taken on a female vocalist to front their carefully measured wall of sound (Maria Vastano). Her voice never quite lilts, never panders, never sounds dispassionate, like a statue of the virgin Mary amidst a raging battlefield. She knows when to stand in shadows, and when to strike for the kill. The guitars charge, they race, they let chains of notes fall like Spanish classical music. The bass, perfectly married to the kick drum, walks into melodies with an effortlessness that can't help but ridicule what passes for bass guitar on most radio stations today. The drums - ah, the drums! - of Eternal Essence are their proverbial backbone, laying back and providing support from behind, right up to the crucial moment when they sharpen up to a staccato machine gun of head-rapping ecstasy, firing volley after volley of beautiful violence, carefully measured and white-knuckled in their triumphant lack of mercy. Plenty of drummers idolize Neil Peart of Rush, but the Peart-like percussion of Eternal Essence practices and does not preach.
There are crystalline keyboards, clean-channel strings, crashing cymbals like toppling walls... But the important thing is that the nation of music fans know: Eternal Essence is here, and they have a new album.
-Sean McCauley
MondoTunes Staff Writer
The LP "A Light in the Distance" is distributed globally by MondoTunes ( http://www.MondoTunes.com ) and is available at iTunes for convenient purchase and download
Address - 607a north Victoria Ave. Ventnor, NJ, 08406
Phone - 609-457-7014
eMail - email@example.com
website - http://www.reverbnation.com/eternalessence


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I think there can be, and it can be either a positive relationship or a negative one, and the key is consciousness.
If we desire to do harm, we use sports as training for killing. This is part of their history, as in medieval jousting competitions and military martial arts competitions.
If we are not conscious, then sports partially works out, and partially encourages, our destructive and hateful impulses.
If we are very conscious, we can use sports to channel energy that would otherwise be destructive into fun, wise, and healing activity. I am a pacifist and meditator (practitioner of loving awareness and mindfulness) who practices martial arts in this way (though I don't fight others). In the move Ip Man 2, the character Ip Man (played by Donnie Yen) says, "By fighting this match, I'm not trying to prove that Chinese martial arts is better than western boxing. What I really want to say is, that, while people have different positions in life, everybody's dignity … we are all the same. I hope that from this moment on, we can all start to respect one another."
That, I believe, is the highest conscious transformation of our destructive desires through the medium of sports.
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The term "great all-around athlete" is often thrown around in reference to top high school football recruits. Sometimes the term is probably used a little bit too much, but when it's used in refer...
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Talking at the new F10 M5's press launch in Spain project leader, Max Ahme did not confirm the approval of a AWD M5 already but he said that is very possible.
"We are thinking about it", said Ahme. "If you are increasing power more and more, maybe you need it." He does admit though that this solution does come with certain disadvantages.
What type of AWD system BMW will use? Ahme mentions that the company has already studied the Ferrari FF's lightweight AWD solution, but will more likely use a traditional AWD system.
On the same time, M Division Product Management Chief Jorg Herrmann said that BMW M is looking at whatever means it needs to get the job done, regardless of tradition.
"If technology changes over time the character of this model had to be changed and evolve," he said.
The new M5 is bigger than ever before, putting on 55 millimeters in length and 46 millimeters in width over its direct predecessor.
While the engine is technically taken from the X5/X6 M engine bay, its dual twin-scroll turbocharged unit has been significantly adapted for this application. BMW claims all 500 lb-ft of torque is available from a mere 1500 rpm all the way to 5750 rpm, with redline coming in at 7200.


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Staff and Instructors
Andrew Welch, Director
From 2012 to 2013 Mr. Welch served as University Programs Division Chief where he led program management, operations, and academic initiatives for the organization's university-based research and development program and college leadership training pipeline of over 150 students on 15 campuses across the United States. Previous assignments include service as Deputy Director of Strategic Planning, Commander of Flotilla Northern Virginia, Marine Safety and Environmental Protection Officer, Unit Officer in Charge at The College of William and Mary, and Public Affairs Officer of the Virginia Peninsula Division based at Training Center Yorktown. He has served on the Coast Guard's Evergreen long-term strategic planning "Core Team", and on the Commandant's Innovation Council.
Charles Mccarty, Division Chief
Charles McCarty is the Division Chief of the Auxiliary University Programs with responsibility for managing the program nationwide. He has served as Flotilla Commander, Division Vice Commander, SO-MT, SO-MS, FSO-MT AND FSO-MS along with other staff positions. He is certified as an Instructor, Vessel Examiner, ATON Verifier and AUXSC&E Instructor and has earned the AUXOP AND RBS Devices. He was involved in the standup and operation of the AUP Unit at the State University of New York at Canton. Mr. McCarty is retired from a career in criminal justice, judicial administration, and academia.
Kathleen jennings, program management branch chief
Kathleen Jennings is the U.S. Coast Guard Auxiliary University Programs (AUP) Program Management Branch Chief. In this capacity, she serves as the deputy to the Division Chief and oversees the administration of AUP. Ms. Jennings previously served as a Branch Assistant for Academic Affairs. She began working with AUP in 2012 and has an extensive background in education. She sits on the School of Education Development Board at The College of William and Mary.
Graig Arcuri is the U.S. Coast Guard Auxiliary University Programs (AUP) Branch Chief - Operations where he has responsibility for maintaining accountability, responsibility, and authority for AUP operations nationwide; managing the portfolio of all AUP units, assigning each unit to subordinate Operations Assistants so that each is responsible for approximately 6-7 units. He is a qualified vessel examiner and crew and currently serves as Commander of Flotilla 092-02-04, as well as, FSO-OP, FSO-MA, and FSO-DV. New to AUP, he comes with substantial operations and academic experience, which currently includes being a member of the faculty at The State University of New York at Oswego and Syracuse University.
Richard R. Young, Ph.D, Academics Branch Chief
Richard Young is the U.S. Coast Guard Auxiliary University Programs (AUP) Branch Chief - Academics where he has responsibility for maintaining accountability, responsibility, and authority for academic activities in the areas of Leadership, Nautical Science, Communications, Marine Safety, Vessels, and Public Affairs, ensuring that responsibility for each is shared amongst subordinate subject matter experts. He is a qualified vessel examiner and instructor, and serves as Assistant District Staff Officer for Incident Management and Preparedness for the Fifth Northern District. New to AUP, he comes with substantial academic experience having been Director of Graduate Programs for the School of Business Administration at The Capital College of The Pennsylvania State University.
jake shaw, AUP Senior Advisor
Jake Shaw serves as the U.S. Coast Guard Auxiliary University Programs (AUP) Senior Advisor, responsible for using his 10 plus years of AUP knowledge and experience to complete special projects and maintain overall program health. He supports the DVC and other branch chiefs. Mr. Shaw is a qualified Coxswain, Vessel Examiner, and Public Affairs Specialist. He and his videographer documented the Coast Guard Auxiliary's service during the Deep Water Horizon's Spill of National Significance (SONS) in the Gulf of Mexico. Mr. Shaw has been with the Auxiliary University Programs since its inception. A Physical Therapist and Athletic Trainer, Mr. Shaw's professional background has included service with the Auburn University Athletic Department and as the Orthopedic Senior Physical Therapist for East Alabama Medical Center. He sits on the Board of Advisors for the Warrior Athletic Training and Warrior Research Center at Auburn University, which serves the U.S. Army at Fort Benning, GA. Mr. Shaw is also a Community Emergency Response Team (CERT) instructor, former SCUBA Dive Master, former Water Safety Instructor trainer, and former sailing instructor.
MK3 Jesse Thrift
Juniors Program Lead
Mr. Bill Iwanyk
Seniors Program Lead
Ms. Katie Mazzola
Division Leader
Background: AUP Senior
mST1 Blaine Meserve-Nibley
Operations Manager - Maritime/Military Units
Background: Marine Science Technician
Mr. Joshua Kingett
Operations Manager - Northern Units
Background: Boat Operations
LTJG Landon Elliott
Operations Manager - Southern Units


text: When I hook my phone up to a computer to charge (I just hit "Home" when it asks me what mode to put it in) the Wi-Fi will not work. The meter is showing a good signal, and the phone is indeed connected to the network and received an IP, but will not send/receive packets. As soon as I disconnect USB, the Wi-Fi begins to work again. I have checked the "Never" option on Wi-Fi sleep but this problem persists. Any ideas?


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GraphicRiver New Generation Leader 8095811
Stock Vector \ Characters \ People
Leader \ Creative \ Casual \ Stands \ Generation \ ManNew \ Smiles \ Included
Stock Vector - New Generation Leader 8095811 by koctia @ GraphicRiver
Stock Vector \ Characters \ People
New generation leader of the creative team in casual wear stands with arms crossed and smiles. Hi-res jpeg (300 dpi) included.
Layered: No; Graphics Files Included: JPG Image, Vector EPS; Minimum Adobe CS Version: CS.
Social Media in Local Business; Digital Marketing Team Avatars; Smart Devices in Local Business Marketing; Local Area Navigation Icons; Wearable Devices in Modern Business; Location Based Targeting; Local Store SEO Concept.
Keywords: bookshelf, business people, businessman, cartoon, casual wear, concept, creative, designer, desktop, employee, freelancer, illustration, industry, leader, leadership, manager, occupation, office, portrait, self-employed, standing, teamwork, vector, worker, workplace, young man.


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Published: Wednesday 1st April 2015 by The News Editor
Justice Secretary Chris Grayling's policy of excluding prisoners from being transferred from closed prisons to more lenient open prison conditions if they have a history of absconding has been declared unlawful by the High Court.
The policy was introduced following high-profile media reports last year of prisoners with a history of violence absconding while on release on temporary licence (ROTL) from open prison.
Among them was Michael Wheatley, a fugitive armed robber nicknamed the Skull Cracker.
Mr Grayling publicly announced last May that the Government was "tearing up the system as it exists at the moment" and introduced his absconder policy.
But two senior judges at London's High Court have ruled that excluding transfers – save in exceptional circumstances – for prisoners "with a history of abscond, escape or serious ROTL failure" is inconsistent with his own directions to the Parole Board.
The long-standing directions state that "a phased release" from closed to open prison is necessary for most inmates serving indeterminate sentences "in order to test the prisoner's readiness for release into the community".
Lord Justice Bean, sitting with Mr Justice Mitting, gave the Justice Secretary permission to appeal against the court's ruling.
The Prisoners' Advice Service, a charity offering free legal advice and support to adult prisoners, described the absconder policy as a "knee jerk reaction" by Mr Grayling.
The charity said in a statement: "The Secretary of State's contention that he is entitled to ignore and contradict his own policy guidance demonstrates either his ignorance or flagrant disregard for basic legal principles of consistency and transparency in public decision making.
"The so called 'absconder policy' was introduced as a knee jerk reaction to negative press reports without adequate consideration for either existing policies, or its impact on the prisoners whose progression to open conditions was abruptly prevented."
The policy was introduced after press reports early last year of prisoners absconding.
High in the headlines was the case of Michael Wheatley, a fugitive armed robber who was nicknamed the Skull Cracker.
Wheatley, who had been given 13 life sentences but was eligible for release after eight years, had been on the run after leaving Standford Hill open prison in Kent on day release and failing to return.
He was arrested alongside another man in Tower Hamlets, east London, after an armed robbery at a Chelsea Building Society branch in Sunbury-on-Thames, Surrey.
The Ministry of Justice announced there would be an appeal.
A spokesman said: "The fundamental principles of the policy are not unlawful.
"The court found there was inconsistency with the implementation.
"Our position remains that temporary release can be an important part of rehabilitating offenders but not at the cost of public protection.
"We are appealing this decision."
Published: Wednesday 1st April 2015 by The News Editor


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Share a photo of your hand-written pledge of how you commit to reduce your greenhouse gas emissions and you could win a prize.
We're drawing one winner per month.
The draw ends October 30, 2017.
Greenhouse gases come from burning fossil fuels (gas, natural gas, oil, and so on), methane emissions, from landfills and natural sources.
Here are some ideas to inspire you to reduce these gases:
Prizes will be awarded by random draw. Random draws will happen each month, starting in June of 2017.
Win a three month adult Flexipass for Vancouver Park Board fitness centres, swimming pools, and ice rinks in August.
Learn more about the Flexipass.
To enter the contest, share a photo that you took of your handwritten pledge to reduce greenhouse gas emissions:
The contest is open between noon on May 10, 2017, and 11:59pm on October 30, 2017.
Photos must be appropriate for posting on a public government website. Photos that contain obscene, provocative, defamatory, sexually explicit, or otherwise objectionable or inappropriate content will not be considered. We will determine, in our sole discretion, what constitutes such content during the moderation stage of submission.
We reserve the right to remove or replace any files that compromise the security of our Twitter account, Instagram account, website, and other City information technology systems, or are otherwise malignant.
Only one prize will be awarded per person. The prize must be accepted as awarded, are non-transferable, and cannot be redeemed for cash.
If you are an employee of the City or its related agencies, you are not eligible to win.
If you are under 18 years old, make sure to have parent or guardian consent to enter.
By entering this contest, you give the City of Vancouver permission to reshare your photo with no identifying information.
Your personal information will be used for the sole purpose of entering this contest, will be deleted after we pick a winner and will not be sold or shared with third-parties. Your personal information is collected, pursuant to section 26(c) of the Freedom of Information and Protection of Privacy Act, solely for the purpose of administering this contest. It will be destroyed upon the determination of a contest winner. Please direct questions about this privacy policy to the City of Vancouver at email@example.com.
Expand the images to read a short comic about sea level rise, why it's happening, and what we all can do about it.


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The Berlin Film Festival is now underway in Germany, premiering some of the best new international cinema in 2012. Each year the festival sells around 300,000 tickets, making it the largest publicly attended film festival in the world. It is visited by film industry professionals from over 115 countries, with the best films receiving the prestigious Golden and Silver Bears. Last year's winners included 'A Separation', which went on to be featured in festivals worldwide and is now Oscar nominated.
The festival also has a World Cinema Fund, which spends around 400,000 EUR annually in countries with weak film infrastructure. It ensures feature films and documentaries get produced and distributed where they otherwise wouldn't.
Below are some of the films we're excited about seeing, and some that are getting major buzz at the Berlin Film Festival this year.
In the Land of Blood and Honey – Angelina Jolie's much-anticipated directorial debut is set amongst the Bosnian war, following the relationship between a Muslim artist and a Serbian policeman. Their pre-war relationship takes a radical turn when they meet again in a prison camp – she an inmate, he a guard.
The Flowers of War – This much-heralded Chinese epic gets its first European screening at the Berlin Film Festival. Director Zhang Yimou's film retells the horrors of the Japanese invasion of Nanjing in 1937 (also known as Nanking). Christian Bale stars as a mortician who must protect a group of students from the invaders.
Marley – Made in co-operation with his family, this documentary aims to be the definitive account of the life of musical icon Bob Marley. Directed by Kevin MacDonald (The Last King of Scotland), this is the world premiere of this hotly anticipated film.
Iron Sky – With one of the greatest taglines ever – "In 1945 The Nazis Went To The Moon. In 2018 They Are Coming Back" – this comedy premiere should become a cult favourite. From director Timo Vuorensola and the team behind satires such as 'ÄòStar Wrecks', this Finnish film about Nazis in space is sure to be a Festival highlight.
The Flying Swords of Dragon Gate – Wuxia martial-arts master Tsui Hark is back with his first ever 3D film. Jet Li stars as a warrior searching for a missing woman, in this remake of Dragon Gate Inn (1966). Fans of Hark's gravity-defying fight sequences and flying weaponry will be in heaven as it leaps out of the screen at Berlin this year.
Check out the full program here, and let us know your picks of the 2012 line-up on our Facebook.


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Northern leader under the aegis of Arewa Consultative Forum (ACF) have said that every northerner has the right to contest the 2015 presidential election, noting that President Goodluck Jonathan was given the mandate to spearhead the affairs of the country for only four years.
According to the National Publicity, Mr. Anthony Sani who disclosed this recently, the emergence of President Goodluck Jonathan in 2011 as president has cancelled the zoning system in the country.
He said: "President Jonathan was given the mandate to rule the country for four years, and he is in his second year, we should allow him to finish before talking of who will be the next president"
Sani further explained that the issue of zoning is dead, as according to him, "North will contest the presidency come 2015, but it is not going to be on the basis of zoning, Nigerians have passed judgment against zoning since the emergence of Goodluck Jonathan as President in 2011, instead of allowing the North to continue after the demise of late President Umaru Yar'Adua".
Speaking further, Sani noted that talk of 2015 election now is irrelevant, "This is not the time of politics, but when the time comes, the North will surely contest for Presidency," he said.
On the current issue of insecurity in the country, Sani said it needed a collective approach led by the Federal Government. He pointed out that, "security is everyone's business as we must come together collectively, irrespective of religion, tribes, region or ethnicity to solve this problems in the best interest of the country."
He blamed the present security situation in the country to poor leadership and appealed to the leaders in the country to sit-up in order to tackle the problems confronting the country.
While disagreeing with those calling for the division of this country, the ACF spokesman avowed that"nobody can divide the country, God knows why He kept us together and we shall continue to be together for unity, peace, progress and the overall development of the country".
Source: Naija.ng


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With this ninth edition, Read, Reason, Write becomes 25 years old and although some important new material strengthens the ninth edition, the essential character of Read, Reason, Write remains the same. This text still unites instruction in critical reading and analysis, argument, and research strategies with a rich collection of readings that provide both practice for these skills and new ideas and insights for readers.
Through all of its years, this text has been committed to showing students how reading, analytic, argumentative, and research skills are interrelated and how these skills combine to develop each student's critical thinking ability.


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Rwanda at a glance
Capital: Kigali
Rwanda is a small landlocked country in East Africa. It is bordered by the Democratic Republic of Congo (DRC) to the west, Tanzania to the east, Uganda to the north, and Burundi to the south. The population is rural and young; approximately 43% are under age 15 and an estimated 90% are subsistence farmers. Coffee and tea are the main cash crops for export.
The 1994 genocide did significant damage to Rwanda's fragile economic base, severely impoverishing the population and temporarily stalling the country's ability to attract private and external investment. However, Rwanda has been able to make important economic and structural reforms and sustain its economic growth rates over the last decade. GDP has rebounded with an average annual growth of 7% - 8% since 2003 and inflation has been reduced to single digits. Nonetheless, as of 2015, 39% of the population still live below the poverty line, according to government statistics, compared to 57% in 2006.
Rwanda is trying to overcome the limitations of its small, landlocked economy by leveraging regional trade. Rwanda has embraced an expansionary fiscal policy to reduce poverty by improving education, infrastructure, and foreign and domestic investment, and pursuing market-oriented reforms.
The country has also made remarkable progress since 1994, particularly in promoting good governance and delivering essential services to the poor. Rwanda is known worldwide for its good governance record and zero tolerance for corruption and promotion of gender equality.
UNICEF in Rwanda: Country Profile
(PDF documents require Acrobat Reader to view.)


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cold Cure
From: Winston Campbell Subject: COLD by The Cure Cold (words by Robert Smith, music by Simon Gallup, Laurence Tolhurst, and Robert Smith) This gloomy song comes off of the angry and gloomy cure album -Pornography- and never lets up for air. I am not too sure about what is playing that line, a distorted bass, guitar, or keyboard but I have comprised it to be like this: I play this usual, meaning I tune my low E-string down to C. The intro is: E -------------------- B -------------------- G -------------------- D -----------4-------- A -1---3--4------4--3- C -------------------- After this, the drum enters, and the bass (or guitar) goes like this (as if played on a guitar with its low string tuned to C): E ------------------------------- B ------------------------------- G ------------------------------- D ------------------------------- A ------------------------------- C -10---------8--5--6-------0--1- This line continues out throughout the song. The chords are simple, they are just Bbm to Gb and I play them like this: Bbm Gb E -xx---------------6------------ B -11---------------7------------ G -10---------------6------------ D -11---------------x------------ A -xx---------------x------------ C -10---------8--5--6-------0--1- That is basically how the song goes. The lyrics are: Scarred Your back was turned Curled like an embryo Take another face You will be kissed again I was cold as I mouthed the words And crawled across the mirror I wait Await the next breath Your name Like ice into my heart A shallow grave A monument to the ruined age Ice in my eyes And eyes like ice do not move Screaming at the moon Another past time Your name Like ice into my heart Everything as cold as life Can no one save you? Everything As cold as silence And you never say a word Your name Like ice into my heart Your name Like ice into my heart
Important: The song above is NOT stored on the Chordie server. The original song is hosted at tabfu.thudspace.net. Chordie works as a search engine and provides on-the-fly formatting. Chordie does not index songs against artists'/composers' will. To remove this song please click here.


text: I was doing some comparisons of Curse of the Black Pearl with my SD version against the BD version and noticed in the scene when the Pearl first shows up & Jack goes up to the cell window that his head was cut off and it was clearly in the shot in the SD version. I start checking picture aspect ratios and tv and player settings -- long story short, I get on the web and sure enough there's a framing problem with early discs. I got this from Amazon this week, this problem was noticed in 2007? They're still selling the "bad" copies of these!? Sheesh, I'll have to write Amazon. Does Disney still offer an exchange? Also, the color is different, I mean, the DVD version seems 'warmer', jail scenes (in the beginning), when the maid is putting the coals in the pan for Ms Swann (Kiera), and Will (Orlando) in the black smith/sword making shop (all before the pirate attack) seem to have more of a 'glow' about them. Has anyone else noticed this? I'm not saying it's necessarily 'better' just very different, is this normal? Are there any known issues with discs 2 and 3 that I should be aware? TIA,


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But coupled with this wrong perception of fullness will come a number of prospective overall health problems, from dry mouth and constipation to increased blood pressure and insomnia. Even worse, the moment you prevent using these prescription drugs, the burden will little doubt return, and also your system is remaining in a worse condition than it was ahead of you started off using the drugs.The choice is not any prescription diet tablets, which normally refers to around the counter organic nutritional supplements with nutritional vitamins, minerals, herbal extracts and other vitamins and minerals that may support advertise weight reduction.
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TENA Comfort Pants
Pack of 2
Product Overview
TENA Comfort Pants
Tena Comfort Pants
AllegroMedical.com presents The Tena Comfort Pants offered from Sca Personal Care Inc. Designed to support and hold Tena® pads in place, prevents sagging during wear for longer lasting comfort and secure pad protection without shifting, helps prevent "red leg lines" on the skin surface to protect skin, to better hold the Tena® pads in place, up to 50+ times washable under recommended laundering conditions.
- Single color coded waistband for quick and easy size selection.
- Deep waistband and seamless sides construction for improved comfort and discreet fit.
- High "Stretch Memory" material design.
- Non-binding leg hem design.
- More defined crotch.
- Washable and reusable.
Place Your Order Here
TENA Comfort Pants
TENA Comfort Pants Reviews Summary
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Part Number(s): 098 573151 01, 098 573151 02
Mfg Part Number(s): 36055, 36066
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ravingscientist01 on When an anti-science mob has i… editor on When an anti-science mob has i… H. Alatas on Séralini did it again! ravingscientist01 on Séralini did it again! Jeanne A. Pawitan on Séralini did it again!
Category Archives: Computing
Open-source in academia and research charities
I discovered GNU/Linux in 2005, by attempting to install Ubuntu in a dual-boot with Windows XP. Windows got wiped out in the process and I was left with Ubuntu. This was kind of a fortunate mistake, because I never looked … Continue reading
Posted in Computing, Linux, Policy, Science Leave a comment
Boy this distribution does look good!
Last week, while browsing the web to learn what was happening in the Linux world, I read a post about a distribution that has a "half rolling release" model. I got immediately interested, and here's why. For my home computer, … Continue reading
Posted in Computing, KDE, Linux Leave a comment


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ja! studio has been creating shop windows for the clothing company Loreak Mendian under the concept of transmitting the essence of the Brand through smalll installations on a monthly basis. There is no better word to describe the aim of the conceptual windows in San Sebastian, Madrid, Barcelona and that is: provoke!
The marketing department meets every semester to develop series of displays and determine on a product on which to focus each month. Once done the window dresser makes up the ideas and the window design is set. The setting consists of a diaphanous space (white, in most cases) that covers an area of 6x 9.50 sq (m2).
Sockets and rails on the ceiling are usually used in order to give the chance to create different atmospheres. That's why most of the windows also have dual, night and day, lighting system. The items used in displays range from digital productions, waste material, daily utensils to specifically designed items tailored made for a job. Synthetic paint with different finishes, cardboard, shellacked wood or vinyl are some of the materials to be taken into account when performing a display.
All pics & info courtesy of www.yatzer.com
Read the rest here :
sources: ja! studio
you are who you decide to be...Adapt & Overcome.


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Mestige Skipping Stone Bracelet
Don't pay more to add a little sparkle to your life!
Dual rows of crystals with intermittent middle row crystals!
Rhodium colour plated | Perfect gift for yourself or someone special!
Due to the nature of this product, this item will be posted individually - but don't worry, postage is included! It MUST NOT be delivered to a PO Box. Please ensure your address details, complete with contact number, are updated in your account.
Set the scene with a splash of Mestige Made With Swarovski Element sparkle. Perfect as a gift for yourself or for that special someone, this gorgeous bracelet made with 96 crystals is sure to impress even the most discerning recipient, and will complement any outfit choice with its fine Rhodium plated finish, sparkling at any angle.
- Sparkle & shine with this gorgeous jewellery from Mestige!
- Mestige Skipping Stone Crystal Bracelet Made With Swarovski Elements
- Rhodium colour plated setting
- 12 x 5mm crystals made with Swarovski elements
- 84 x 3mm crystals made with Swarovski elements
- Perfect gift for yourself or someone special


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Category: Stock Graphic, Product Mockups
Stock Graphic >> Product Mockup - Yosemite GUI for illustrator 256807 by CM Design Kits @ CreativeMarket
File Size: 72.4 MB; Vector: Yes.
Yosemite GUI Template for adobe illustrator. It's 100% vector and very precise. Perfect for your app design.
Keywords: illustrator, ai, vector, gui, ui, ux, yosemite, mac os x, apple, app, design, mac, software.


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The plum sake turned out very well, pure nirvana. This is MHO and the opinion of 15 party goers last Saturday. It is just as good as 'Nagasaki Black Orchid Plum "Junmai Ginjo Sake" 375ml $12 Handcrafted, super-premium Junmai Ginjo Sake made with natural Santa Rosa plums. '
This is in spite of my many screw ups.
I made no additions at yodan.
September 20th, added plum wine made with sake yeast and sake together in 5 gallon carboy.
"Then just siphon the sake out from under the kasu (粕) - the rice lees that are floating on top of your sake."
The kasu was all at the bottom.
"Then take the kasu and pour it into a nylon or canvas mesh bag (if you have a small fruit press this will be a lot easier) and press as much sake out as you can."
The pantyhose were too weak and so was my left knee.
The racking process was a mess.
The 'must' was cloudy
'Must' kept at 50F.
On 10/11 heated two packs gelatin in one quart of boiled cooled water and drizzled into 'must' for clarification.
This did not work.
Added approx. ½ cup of sugar to each 3 qt of pretty, light pink, plum sake and heated up to 140 F.
ROTFLMAO when I pasteurized the plum sake in 750 ml corked bottles at 160 F and the corks in the bottles popped out like popcorn.
Started over with temporary rubber/ spring stoppers and let loose the pressure every 2 minutes for 10 minutes.
Re corked immediately after moving bottles from water.
Every bottle has some 'lees' in the bottom. Spilled about a bottles worth and one cheap, light green bottle broke in the 160 F water. Ended up with 18 bottles.
Next year I will do one, some, or all of the following;
Get a strong mesh bag to rack the plum wine and sake with
Get a small fruit press for this process
Grind up the calrose rice a bit before using
Use fancy rice grown for sake
And, I will use temporary spring corks for pasteurization.


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Nylon Spandex Solids
Nylon spandex is the preferred fabric for leotards, active lifestyle garments, swimwear, and athletic attire. It has been commonly used since the 1960s, and is known not only for its expandability, but also for its light-weight, breathable features and durability. We offer spandex solid colors and spandex patterns, and our fabric varieties are ideal for many different applications. Many vendors and individuals purchase fabric to create their own spandex clothing since the fabric maintains its integrity through prolonged exposure to cosmetic products and natural oils. Our nylon spandex is available in football, heavy compression, tricot matte, tricot shiny, jersey, and super stretch varieties in order to facilitate many different uses.
Website : spandexbyyard.com


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Brutal Trailer (2007)
10 July 2007 Horror, Crime, Mystery 91 mins
In a small town, a serial killer mutilates the bodies of his victims and leaves a flower on the corpses. The sheriff and his wife/deputy investigate the murders while trying to keep from alarming the citizens. They team up with an autistic hound dog trainer to try to track the killer.
Watch the official Brutal 2007 trailer in HD below or find more Brutal videos on Vidimovie.


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Label Spotlight | Fly Eye Records
What do DJs do when they're not producing songs or playing at huge festivals? Well, if you're world's highest-paid DJ Calvin Harris, you're putting some of that $46 million into managing your own record label. In 2010, Harris decided to create his own vanity label and named it "Fly Eye Records" after his signature fly-eye sunglasses that he handcrafted himself. (There's a whole other story behind that and it involves a lot of Swarovski crystals).
DJs With Their Own Vanity Labels
These days, it's not uncommon for DJs to found their own labels while still working under the major label they're signed under. Some other DJs who founded their own vanity labels include Deadmau5 with "mau5trap", Boys Noize with "Boysnoize Records" and the well known "Armada Music" was co-founded by Armin van Buuren himself. Although vanity labels have been scrutinized for being nothing more than ego boosts for entitled pop stars, their original purpose was for successful recording artists to scout other artists that they admire without the contract restrictions of a major label. When Harris established Fly Eye Records he made his intentions very clear by stating, "My goal for Fly Eye Records is to release the most exciting club music I can get my hands on. There will be absolutely no shite." And absolutely no shite has there been.
Fly Eye Records Artists
The label launched itself into success from the very beginning with their first single "Gecko" by Mr Blink which received a lot of attention and support from well established DJs like Wolfgang Gartner, Benny Benassi and Markus Schulz. Since its triumphant kick-start, Fly Eye Records has released a series of catchy hits that even the radio couldn't ruin. The various innovators of Fly Eye Records includes Michael Woods, Bassjackers, GTA, Hard Rock Sofa, Thomas Gold, Nicky Romero as well as the man who discovered Harris, Tommie Sunshine – and that's just the tip of the iceberg. Fly Eye Records has been a silent contender in the EDM game over the past few years. Although the label has yet to become a household name, it has already released notable crowd favorites such as Dillon Francis' "Bootleg Fireworks (Burning Up)", Firebeatz's "YEAHHHH" and "Iced Out" by BURNS along with many of Harris' own singles.
To get a true grasp of what exactly makes up Fly Eye Records material, I'd suggest listening to Firebeatz's 2013 Beyond Wonderand set. Not only does the Dutch duo stay loyal to the label by playing their co-workers tracks but they successfully blend in bangers with tech house, Deorro with Andrew Bayer, Jacob Plant with Eric Prydz, and a whole lot of Calvin Harris in between.
From Producing to Managing
Harris himself has come a long way from being a budding musician who once hosted a YouTube show called "JAM TV" where he invited celebrities to come over to his place and try to open packets of jam (a strange alternative to Deadmau5's coffee run) to attracting the second largest crowd in Coachella history at this year's Coachella. Now Harris without a doubt has become a successful DJ but will his label management prove fruitful as well? Could one of these names be the next superstar DJ in the making? I'll let you decide! Here are Fly Eye Records' latest releases, "Throne" by Sandro Silva and "Switch" by dBerrie and Zen Freeman.
Lalita Stone
Latest posts by Lalita Stone (see all)
- "Call 911 now!" and Other Epic EDM Samples - September 13, 2014
- Zedd remixes summer anthem "Rude" - September 3, 2014
- 2014's Highest Paid DJs - August 25, 2014
- These DJs accepted the ice bucket challenge. Have you? - August 19, 2014
- Dillon Francis Announces New Album and Tour - August 12, 2014


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Yes, I'm still alive. It's been over three months now without blogging, and yes it's crazy!
Apart from being a Sr.Consultant and a TAM at VMware with 100% utilization in this huge and active region, I've been also doing lots of reading and studying lately to prepare for the VCAP exams. Not to mention my growing obsession with the Redwood project whether through testing and evaluating it, or following its daily discussions on our developers & PMs mailing lists. Add all that to the frequent traveling and you won't find a time to scratch your head!
I won't take much time in this introduction, so straight to the point: I decided to start a newsletter (or whatever they call it these days). I have to admit though that this is not my most original idea. Firstly I was inspired by one of my colleagues in VMware (Michael White – who's also one of the SRM legends out there). He has an internal weekly newsletter with lots of invaluable information and I really enjoy reading it! I thought of doing the same on my blog, but I wasn't sure about this idea until I started receiving another mind-blowing weekly newsletter written by our CTO, Steve Herrod. At that point I realized that I'm a newsletter person and I do like the idea of having everything consolidated in one place at a time. I won't do this letter however on weekly basis, at least at the beginning. Let's make it casual every two weeks or so until I see my readers feedback.
At least I get to blog, and that's all what it matters. Here we go.
News flash: vSphere 4.1 is released!
Yes the debate around the numbering (4.1 Vs. 4.5) is finally over. Most of this debate was driven mainly by the fact that it's a quite powerful release with major enhancements and rich features normally found only in major releases. There is no point of copying and pasting the release notes here if you can read it directly on VMware's website. Here you go:
- For ESX Classic : http://www.vmware.com/support/vsphere4/doc/vsp_esx41_vc41_rel_notes.html
- For ESXi : http://www.vmware.com/support/vsphere4/doc/vsp_esxi41_vc41_rel_notes.html
The password issue with ESX/i 4.1
You've probably heard about the 8-char password issue with ESX/i 4.1, but in case you haven't heard yet about its solution, you can find the details here in this KB article:
VCB Support in vSphere 4.1
I had a couple of customers asking me about the VCB support and whether it has been removed, and the answer is no. VMware extended the support in 4.1, but I personally recommend moving to the vStorage API for Data Protection (VADP) in case you are upgrading or starting a new vSphere environment.
From our internal mailing list I also quote this: "Several backup vendors have released VADP based backup solutions. These include VMware Data Recovery 1.x, Symantec NetBackup 7.0, Symantec Backup Exec 2010, CA ArcServe 12.5, EMC Avamar 5.0, IBM TSM 6.2, Veeam 4.0 and VizionCore 4.5"
vSphere on IBM BladeCenter H Part II
I've been getting many questions about the second part of the BCH, and when I will release it. I actually finished nearly all the Visio diagramming, but the problem is simpler than this. The HX5 and Virtual Fabric expansion card from IBM are not been certified yet by VMware! I was really hoping that both will be on our HCL by the release of vSphere 4.1, but nothing so far. I see no point to publish my article if you won't be able to use it. Besides, it can cause lots of unnecessary confusions to the partners and customers. I won't leave you disappointed however, and I'll direct you to an awesome new redpaper written by IBM on the Virtual Fabric.
Mobile Noter for iPad!
Every day I find more value for the iPad! I'm not really into games or apps in general, and my main reason for buying an iPad was PDF reading and web surfing while traveling, but I have to admit that it has a lot more value than that. A couple of weeks ago I came to know about this cool App called "Mobile Noter" and it was like a dream came true! I used to take notes and document things on OneNote since it was released back in 2003, and till this moment I still do. The MN simply allows you to synchronize your iPad with either you desktop over a WiFi network, or to the cloud over 3G or WiFi. I can now have all my notes on the go with me either on the iPhone or iPad, and also keep them all synchronized.
New books:
Interesting 2 books talking about the forensic investigations in our virtualization and cloud computing worlds.
- A Digital Forensic Investigator's Guide to Virtual Environments
- Digital Forensics for Network, Internet, and Cloud Computing
To the partners
I know there are a quite big number of VMware partners subscribed to my blog (as I see from the email domains), so I'll try to keep you updated with any important news whenever applicable.
A new version of the HealthAnalayzer appliance has been released with strong support for the vSphere best practices. Make sure to download, test and patch this appliance to the latest updates before going to the customers. Great tool as it has always been!


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"[...] Four years and a series of catastrophic world events later, the new production, Saturday, is here. It begins with its hero, the successful neurosurgeon Henry Perowne, gazing through the window of his house at what might well be another major calamity: A plane is flying over London, on fire. Thomas Pynchon's Gravity's Rainbow also famously opens with a burning projectile over London, and whether or not McEwan is alluding to it, the comparison is instructive. Pynchon: "A screaming comes across the sky." McEwan: "Above the usual deep and airy roar is a straining, choking, banshee sound growing in volume-both a scream and a sustained shout, an impure, dirty noise that suggests unsustainable mechanical effort," etc., etc. Pynchon's sentence contains no adjectives; McEwan's two clauses contain ten. The desired effect is vividness, proximity; the result is the opposite, with the adjectives muffling the screaming, so that it is no longer screaming but only screaming-that-is-being-written-about. Few contemporary writers are as fixated as McEwan on physical violence; yet no one's prose is less violent than his. [...]."
Wednesday, April 06, 2005
violent prose
via Heikki @pynchon-l:
Posted by Doug Millison at 7:54 AM


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Click the button below to add the Punked Micro Cruiser Tie-Dye Complete to your wish list.
25" x 7" Micro Cruiser Complete - Tie-Dye
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In Ghost of a Chance, Percy's mischiveous ghost was instrumental in getting Ryan and James together. But how did he get to be a supernatural matchmaker? Percy's story is full of romance and tragedy. He wanted true love, but it wasn't easy to find. But when he did, his life changed forever.
©2008 Jade Falconer (P)2013 Jade Falconer
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The Mairie de la Ville de Paris holds an exhibit each year of art work done by employees. As part of the show, florists who are responsible for the Gardens, green spaces, public building plantings, get to show off their creativity. This is the second year that we've been able to see this. Chuck took these great photos for me. Some of the arrangements were very odd, even somewhat unattractive, like that square one in the distance, but most were very lovely. They were displayed in two white tents right in front of the Hotel de Ville (City Hall.)
An ice skating rink is being set up in the plaza and hoping it'll be finished before we leave, so we can show it to you.


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Autodesk AutoCAD MEP 2017 HF3 x86-x64 RUS-ENG
Software Version: 220.127.116.11 (2017 Build N.52.0.7)
Language: English / Russian
Description : AutoCAD MEP software - this is AutoCAD for designing heating, ventilation, electrical and plumbing systems of buildings.
Familiar environment AutoCAD provides a higher accuracy of documentation on engineering systems.
Automation of drawing operations and collision detection function to help increase productivity and reduce errors.
Support of the project of engineering systems at construction and at other stages of the life cycle of the building is made possible by a reliable DWG technology.
Support for AutoCAD and AutoCAD Architecture
Automatic calculation of spaces and zones
IFC Data Support
Online help and learning tools
Revision clouds
advanced section
Improved tools documentation
Built-in search function components
Convert AutoCAD blocks and symbols
drawing Management
Custom pipeline tracing
Explorer style
Overriding Properties visibility
The fitting outlet duct
Stratified display order
Replacement units
points Clouds
Search interface elements
Produced by the union of four original distributions in one English x64, x86 English, Russian x64, x86 Russian.
The installer adds the ability to establish a local reference for the English, and for the Russian version of the program.
The installer adds the ability to install the module support VBA-macros.
The installer adds the ability to install the module SPDS Extension 5.0 allows to make out the drawings according to the requirements of GOST 21.1101-2009 (see. Screenshot 7).
Since there was no so-called "classic interface" in AutoCAD 2017 default, I found it possible to restore to the afflicted (see para. 8 screenshot).
The installation package AutoCAD MEP 2017 made integration Hotfix 3 for AutoCAD 2017 products based .
The installation package Autodesk ReCap 360 made integration update from version 220.127.116.11 to version 220.127.116.11.
Autodesk Application Manager utility updated to version 220.127.116.11 to version 18.104.22.168.
Autodesk Desktop App Tool updated to version 188.8.131.52 to version 188.8.131.52.
As used in the original package distributions .NET Framework 4.6 is replaced by the revised version of the project [the Slim] .NET Framework, the x86 4.6.1 of Full / the x64 , with built-in updates as of May 18, 2016.
Added option to cancel the installation, Autodesk Desktop App utility.
Assembling spared from appearing in some problems when connecting through a virtual image of the drive, the installer will sometimes require a different drive.
The combined installer is optimized so that the lost weight ~ 3.5 GB without losing functionality.
Everything needed for the treatment, including detailed instructions, is located inside the image in the folder Crack.
System requirements:
- the WeiRuan-->WeiRuan the ShiChuang 10 (desktop OS), ShiChuang 8.1 with the KB2919355 update, ShiChuang 7 SP1
- 32-bit (x86) or 64-bit (x64) processor with 1 GHz or higher
- For 32-bit: 2 GB of RAM (recommended 3 GB); 64-bit: 4 GB of RAM (recommended 8 GB)
- Video card with a resolution of 1360x768 (recommended 1600x1050 or higher), which provides a full-color palette mode (True Color), and support for DirectX 9 (recommended DirectX 11)
- recommended scaling workspace 125% (120 dpi) or less
- 12 GB of free disk space for installation
- Digital converter with support WINTAB
- the WeiRuan-->WeiRuan of Internet Explorer 9.0 or later
- Adobe Flash Player 10 or later
- .NET Framework 4.6 In addition to 3D-modeling and large amounts of data
- 8 GB of RAM or more - 6 GB of free disk space, excluding space required for installation
- Video card with a resolution of 1600x1050, which provides a full-color palette mode (True Color), with a storage capacity of at least 128 MB, Pixel Shader 3.0 or later, workstation-class graphics card that supports Direct3D
*RG* 2GB Parts
Mirror Links


text: HI all, I have A rooted htc desire. ithas no telstra bloatware, and is running froyo. the android 2.2 one with the software from here: How To: Install Froyo On An HTC Desire | I Can Has Pi? does anyone know where the file is found which has the very first image when you boot your phone - the screen prior to the boot animation ? because itis the last piece of telstra annoyance that needs to go. -Dan


text: Shenzhen Dongdixin Technology Co. Ltd. Shenzhen Dongdixin Technology, based in China, is a leading manufacturer of medical devices. We have been developing, manufacturing and distributing products in the fields of Pain Management and Rehabilitation for more than 10 years. We have 3 main product lines – Infrared Thermometers, Pain Relief devices and accessories. Our pain relief devices included TENS, EMS, Inferential, Microcurrent, Ultrasound, laser/lighting therapy and Electro-Magnetic, EMG. We also have sock, glove and different braces to support the use of these devices. We are ISO 13485 certified and our products are CE0197 approved. Our medical products have undergone many clinical studies in collaboration with different clinicians and health professional. This is to ensure that they are effective in treating different types of pain. It is our MISSION to develop and manufacture reliable, drug-free and high technology products, yet with competitive price, to bring help and relief to patients suffering from PAIN. Our products contribute to better treatment outcomes in hospitals, clinics and at home. With commitment to continuous research and development in our factory, our products have been designed with a distinctly modern look. More importantly, we have devoted ourselves fully to develop more innovative and high technology medical devices. We require that all our products meet the most stringent of demands on quality and safety. The products are manufactured in state-of-the-art production plant with top quality control systems in place to make sure all devices comply with the strictest safety norms and regulations. Our customers can depend on our products with high confidence. Caretalk is a brand of Shenzhen Dongdixin Technology Company. Nu-Tek is a span-new, energetic, and young name in the area of pain-relief and physiotherapy rehabilitation. We have launched more than thirty versions of products on its global debut. The Nu-Tek's products are the result of painstaking research and exhaustive laboratory tests, which are characterized with many competitive features including professional technology supporting, multi-function combination, and convenience of operation etc. Nu-Tek is not only specialized in the drug-free pain relief applications but also in the muscle re-education devices. The former focus on relieving the pain within human's body caused by musculoskeletal, neurological and soft tissue disorders, while the latter contribute to treat urinary incontinence by re-educating pelvic floor muscle and the brain to function on the urinary nerve pathway, and improve muscle strength as well as blood circulation through muscle exercise and the biofeedback of muscle activity. Nu-Tek covers two catalogs of product line. One is the professional physiotherapeutic equipment, and another is the handheld physiotherapeutic device. Professional physiotherapeutic equipment is characterized by a selection of technical, comprehensive, stringent, unparalleled physiotherapeutic equipment. This series consist of wide categories including electrotherapy, ultrasound therapy, electro-ultrasound combo therapy, shockwave therapy, shortwave therapy, and laser therapy. The handheld physiotherapeutic device comes from a section of humanized, convenient, delicate device, including ultrasound therapy and EMG which is customized for female to treat incontinence. As what is said in Nu-Tek's slogan that "Your Partner of quality life", all the work Nu-Tek does is to help people have a quality life, and to gain & share happiness. The desire to build a high-quality life drives the Nu-Tek's products become more and more professional, and humanized. And together with the hope to bring the happiness among people, Nu-Tek will make great effort to achieve this goal. We are committed to continually working with customers to develop devices that can make people's life better.