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Riddle of Berlin by Cym Lowell
- Paperback: 294 pages
- Publisher: IUniverse (June 23, 2008)
- Language: English
My Rating: 4.25 of 5.0
Product DescriptionReview: I was quickly drawn by the action, the terror and the intrigue.
Riddle of Berlin is the story of John C. Jaëgerman. At the plateau of middle age frustration. In Paris, a voice in the water entices his leap from a parapet overlooking the Seine River at Notre Dame. A disfigured body without memory is lifted from the water days later by a gypsy nurse (Carmen) seeking her own path, embodiment of the voice. A campaign of terror engulfs the world. Thousands perish in terrorist incidents in Europe and California. Government is impotent to protect innocent citizens from brutal evisceration. Instigated by a shadowy arms trader, cleverly casting responsibility on others through an Internet site, insurance money laundering and government customers. Riddle of Berlin puts the integrity of NATO on the line, led by popular black American Vice President Lucius Alcorn. A man without fingerprints or history awakens on the Danube. Carmen calls him Del, my deliverer. Orange Girl at the Louvre attracts attention to the declared death of her father on the streets of Paris, becoming engulfed herself in the Riddle. Jaëgerman is deemed the terrorist. Del crafts resolution of the Riddle. Reliving thrills of danger as he tastes new love with Carmen. Denouement brings the choice of everyman. Home is where it was, is or could be? Can we ever return?
John C. Jaëgerman has disclosed a fraud scheme to the executives in his company but no one seems to care. The fight has gone out of John and he walks away. When his bloated body is pulled from the Seine by Carmen he thinks she is an angel. While Carmen is nursing the injured man, her deliverer or Del, back to health, a lot of terror is happening.
Mark Anton is a wealthy young man living in Berlin. He made his riches by developing a website that allows the trading of sports memorabilia. He got the idea for the business plan from his teacher mother, Dr. Lucy Anton. Unexpectedly authorities show up in Mark's home to arrest him for terrorism and treason. Just when they appear, a full blown attack occurs leaving Mark standing with an assault rifle amidst a lot of bodies and a lot of confusion. Mark goes on the run and has one narrow escape after another, leaving carnage behind him each time. His mother is also arrested as a co-conspirator.
Dr. Lucy was a teacher and good friend to the Vice President, Lucius Alcorn. He is already helping with the NATO investigations and is pulled further into the action because he doesn't think his former teacher could be guilty. He thinks the evidence pointing to the "Alton Gang" is too pat and unsupported.
Del/John begins to take back his strong life, rebuilding his previous military honed strength, dedication to the mission and honor. Slowly he remembers details of the past. Coincidence brings Mark to the boat where Del has been sheltered and Del realizes that things are not as they appear. John's name has been linked with the "Anton gang" and his daughter, who came searching for him, has disappeared. Del takes up the battle to find the true terrorists.
Del and Mark, with the help of Carmen, have to stay one step ahead of the terrorist who is out to destroy them. The Vice President is working from a different angle but they are all on a seven day count down before the next bombs are set to go off.
This is good intrigue, fast paced action with a soft romance blended in. Carmen almost has the quality of an angel at times and the only inaccuracy that troubled me was how she went in just a few weeks from not understanding English to being able to follow detailed planning between Mark and Del in what I am sure were English conversations. But if you let that issue slide the rest of the story keeps you turning pages through tense anticipation and sometimes anguished emotion. I also enjoyed the riddled taunts by the terrorist. I recommend this for a fast paced thriller.


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Original paper
Effects of destratification and fish removal on the genus Microcystis in a shallow hypertrophic lake
Lepistö, Lisa; Sammalkorpi, Ilkka; Jokipii, Reija; Niemelä, Maija
Algological Studies/Archiv für Hydrobiologie, Supplement Volumes No. 109 (2003), p. 375 - 386
published: Aug 1, 2003
ArtNo. ESP142014800012, Price: 29.00 €
The boreal Lake Tuusulanjärvi is hypertrophic due to high diffuse and internal loading maintained by hypolimnetic oxygen depletion and a high density of cyprinids. The phytoplankton community, especially of cyanophyta (cyanobacteria, cyanoprokaryota) in the lake is highly diverse, and Lake Tuusulanjärvi has been characterized as a "botanical garden" of the genus Microcystis. The abundant cyanophyta, producing nuisance algal blooms, has generated a need for intensive restoration activities. Since the autumn of 1997, effective destratification and biomanipulation have decreased the internal loading. As a result of lower nutrient levels the phytoplankton biomass, especially of cyanophyta, has decreased and transparency has increased. The biomass of cyanophyta was lowest in summers after the highest removal of fish biomass. During the study period 69 taxa of cyanophyta were identified, High nutrient concentrations clearly explained the occurrence of some morphotypes of Microcystis. M. wesenbergii, M. aeruginosa and M. viridis, which are embedded in a specific kind of mucilaginous sheath, were considered as morphotypes occurring during different phases of stratification. M. wesenbergii and M. viridis were the most resistant species to biomanipulation and destratification.
biomanipulation • destratification • phytoplankton • cyanophyta • morphotypes • resting stage • microcystis

subset: commoncrawl


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Seacoast New Hampshire
& South Coast Maine
Emilio sells lunches and Italian groceries from a one-room shop across from the
US Post Office on Daniel Street - when he's in the mood. If he's not, look for
a piece of wood blocking the window and a locked door.
The sign in the window reads: "Sorry, We're Open!"
Visitors who don't want to make conversation should stay away. Emilio likes to
banter with the customers, and may ask probing psychological questions, offer
advice, tell a joke or sing a song. It's all part of the service. His slogan:
"Our lunch is an Emilio in itself!"
Political exiles from Massachusetts, Emilio and his wife Linda (often seen in
the back room) feed the stomachs, hearts and minds of a loyal crowd of regulars.
In his day, Emilio has been honored in a rap album, featured on the PBS special
"Ciao Italian" and quoted in countless newspaper accounts and recipe books. When
Hillary Clinton visited the shop during husband Bill's initial presidential run
in NH, Emilio told her to keep her eye on him - just as the Jennifer Flowers scandal
broke. This clip even appears in a filmed documentary.
We cannot recommend a meal, since we never know what Emilio will offer. Go for
the Italian tuna if the calzones and pizza are sold out. Frequent favorites include
artichokes, pasta fagioli, beans and rice with spicy beef, meatball or "eggmeat"
subs (eggplant and meatball - our invention), risotto, polenta, "four wheel drives",
fishcakes or, in summer, the "Prescott Park Special", a mixture of whatever is
available ready to take to the waterfront. There may be chutney, salsa, chili,
cold beets, a humus tahini, potato kale soup, rarely a turkey soup, beans, beans
and more beans. Did we mention that we eat here almost every day?
READ: Digitizing Emilios in AS I PLEASE
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text:
29 April 2006
The number of editions of Tears for Fears 'Songs for the Big Chair' continues to increase. 2006 saw the release of a deluxe edition. After a nice dinner and coffee with June at NYDC at the Heeren last night, I dropped by HMV and saw the new deluxe edition. Needless to say, I was astonished. I am tempted to get it just for the those two particular remixes of 'Everybody wants to rule the World' and 'Head over Heels'. However, I have already got the first three CDs here. Do I really need to another CD of 'Songs from the Big Chair'? Maybe, I can display them!
Is this exploitative or what? Is this clever merchandising?
'Songs from the Big Chair'
1. Shout
2. The Working Hour
3. Everybody Wants To Rule The World
4. Mothers Talk
5. I Believe
6. Broken
7. Head Over Heels/Broken (Live)
8. Listen
'Songs from the Big Chair' [Original Gold Master Recording]
1. Shout
2. Working Hour
3. Everybody Wants To Rule The World
4. Mother's Talk
5. I Believe
6. Broken
7. Head Over Heels/Broken
8. Listen
9. Shout - (Extended mix)
10. Everybody Wants To Rule The World (Extended Mix)
'Songs from the Big Chair' [EXTRA TRACKS] [ORIGINAL RECORDING REMASTERED]
1. Shout
2. The Working Hour
3. Everybody Wants To Rule The World
4. Mothers Talk
5. I Believe
6. Broken
7. Head Over Heels/Broken (Live)
8. Listen
9. The Big Chair
10. Empire Building
11. The Marauders
12. Broken Revisited
13. The Conflict
14. Mothers Talk (U.S. Remix)
15. Shout (U.S. Remix)
'Songs from the Big Chair' [Deluxe Edition]
Disc: 1
1. Shout
2. Working Hour
3. Everybody Wants To Rule The World
4. Mother's Talk
5. I Believe
6. Broken
7. Head Over Heels/Broken
8. Listen
Disc: 2
1. Broken
2. Empire Building
3. Everybody Wants To Rule The World (7-Inch Version)
4. Everybody Wants To Rule The World ( Urban Mix)
5. Head Over Heals (? Mix)
6. I Believe (7-Inch Version)
7. Mother's Talk (7-Inch Version)
8. Pharaohs
9. Sea Song
10. Shout (7-Inch Version)
11. Big Chair
12. Conflict
13. Marauders
14. When In Love With A Blind Man
Note: I will get the exact tracklisting for this right soon. Borders doesn't list it. HMV does but it does not specify the remixes. The fan sites are not updated yet. I'm working from memory here.
Near Dark
Last night, I was drawing and listening to this 1987 soundtrack of an obscure proto-Vampire killfest flick that is so common these days. 'Near Dark' pre-dates 'Underworld', 'Underworld: Evolution', 'Buffy', 'From Dusk till Dawn' and others of that irk.
This Tangerine Dream soundtrack is not particularly distinguished. It's alright. Not bad , just nothing really special.
Oh, the guy on the cover looks like one of my friends.
When I was in Shanghai, I did visit one great restaurant. This exclusive restaurant, M on the Bund, is located at No.5, a building housing some bank and it offers an excellent view of the Bund. The prices are easily ten times that of normal cafes and restaurants.
The Australian beef is splendid, easily comparable with some of the better steaks I have eaten in the Asia Pacific region.
I observe that the cliente consisted mainly of the Chinese business elite and Caucasian business people, likely British, Americans and other Europeans.
Do I recommend this place? Well, it really depends on what you like. After all, if you were in Shanghai and you enjoy Shanghainese crusine, I suppose you should go for that rather than Western fare.
No. I don't have photos of the place. I'm not a blogger-journalist and I have no desire to be one. Heh.
28 April 2006
When I was in Shanghai more than a month back, I switched on cable TV and to my surprise, I saw Bill O'Reilly on Fox News. There was the usual CNN, Hallmark, HBO and many many other channels, almost sixty channels in all!
I thought Bill O'Reilly that is a somewhat jingotistic conservative talk show host, what on earth is he doing on Chinese TV?*
*I didn't stay in a hotel. I stayed in an apartment built in the eighties where many the common Shanghainese live.
The Hidden Port
This was originally inspired by the cover of a Robert Charles Wilson book 'Darwinia'. The piece was started a few years back but was unfinished due to a mistake in perspective. And this unfinished piece was dormant for years. Friends and acquaintances have seen the unfinished state and they liked it. A few nights ago, I decided to finish it. First, the second half of the image with the bad perspective was cropped (it lies to the base of this picture and does not appear as such). Subsequently, an image of a towering city in the mists in the game Guild Wars provided yet another idea. And I drew that in. Two hours later, presto. The port is completed. A throwaway piece really.
Pens used: Pilot, Faber-Castell, Rotring, Copic marker. Sizes used: 0.1, 0.2, 0.3, 0.5.
27 April 2006
I went for a run this evening at Toa Payoh Stadium and managed a 15 second improvement over 2.4 km. Late last night, I ran along Bukit Timah Road as it was raining in the evening.
The new SAF-issued Brooks shoes are comfortable. I like them.
It would appear that there may be a hotel at Novena. Hmm.. It will almost certainly be on the large piece of empty land between Novena Square and Tan Tock Seng Hospital
(Business Times, 26th April 2006) "The URA has made available for application a 99-year leasehold reserve list hotel site next to Novena MRT Station. URA estimates that the 62,310 sq ft site, which can be developed up to 261,703 sq ft of gross floor area, could yield about 400 hotel rooms."
That should be interesting.
26 April 2006
Shanghai is not a futuristic city of the 21st century. Old Shanghai exists in large areas of
of the city. They are quite a sight. There are thousands and thousands of folks living in close proximity in these narrow alleys.
A lot of the buildings were once houses and manors built for the British, French and other colonials in the 1920s. Today, there are old Chinese families living there. And there are many families to a single building.
In terms of demographics, young people prefer new towering blocks of glass-clad condominiums with numerous facilities. Thus, it is the old that live in these old haunted structures.
And there are also some that resist moving until a developer comes knocking. New developers and restorationists will pay a lot for these wonderful old manors. Prices have increased more than tenfold. Property prices here are beginning to resemble that of other world cities.
25 April 2006
Pergamon, Logos, Hyperborea
Due to Andrew Glazebrook* mentioning Logos earlier, I pulled out three Tangerine Dream albums from that period and started listening to them again.
- Pergamon: Live at the Palast Der Repubik GDR 1980
- Logos: Live at the Dominion London 1982
- Hyperborea 1983
This is, of course, the period where Tangerine Dream comprised of Edgar Froese, Chris Franke and Johannes Schmoelling. The Tangerine Dream of the early eighties. 'Pergamon' is my favourite from this period.
*Do visit Mr.Glazebrook's blog. He has created an amazing collection of spaceships, planetary surfaces, aliens and more. Breathtaking work.
Well, in reality, nothing much. Heh. I was making good time on round 6 when my SAF-issued* New Balance running shoes finally gave way after years of good service. I guess the pounding of the first round which I completed in 1:37 really did it.
The sole came off. Oh well. Pity about the run. I had 7.75 more rounds to go.
This is either the second or third pair. I can't remember anymore.
On a related note, I have won out more than three pairs of combat boots throughout the years.
*SAF - Singapore Armed Forces
Shanghai may not be Beijing with its vast palaces, gardens and its history, but Shanghai does have a museum with seals, coins, bronze artifacts, stone artifacts, costumes of the minorities, Ming porcelain, Ming and Qing Dynasty furniture. Some of the bronze artifacts displayed date back to several thousand years.
Don't be fooled by the sombre, grey external facade. The museum is lavish on the inside. It is a thoroughly modern structure, not likely to be something from the Commie era.
Here I am, in the People's Square in front of the museum in Shanghai. I think it is well-worth a visit though some of the galleries were closed for a variety of reasons*.
* Loans to other museusm, renovations, etc.
24 April 2006
Lately, I have received several strange telephone calls supposedly from Taiwan. The first incident took place last year when I received a call from a formal sounding lady with an American accent. She claimed to be calling from a court in Taiwan and she had something to convey to my uncle. I informed my uncle who asked me to question her on the matter, but she refused to divulge anything, claiming that it was for his ears only. Then, she hung up!
Earlier this month, the same woman called. This time, she wanted to speak to my mother. She probably could not remember the conversation we had previously. When I received the call, I asked her what it was about again. She repeated the line that she was calling from a court in Taiwan and she would only speak to my mother. Since my mother was not available, she offered to send this information via electronic mail which she claimed was addressed to my mother and was for my mother's eyes only.
This afternoon, she called again asking if I had received the email. I told her either to reveal the object of the call or I would hang up. And she parroted the same line about not divulging information. BAM!
Well, I guess these swindlers are now fishing through phone lines hoping someone will bite. Where Nigerian swindlers once resorted to emails and faxes, now that IDD calls are inexpensive, swindlers probably fish names from trade journals, business listings and so forth.
Wei Yi recommended 'Britannia'. So, on Saturday night, I picked up the FFG remake of 'Britannia' after reading remarks from the original designer that the remake has not been heavily changed or mangled.
The set is lavish! The finish and graphics are splendid. I'm impressed. FFG appears to have done an excellent job on this.
Let's hope FFG will see fit to reprint some of the older Avalon Hill titles. This bodes well.
Dr. Lewis Pulsipher is the designer of Britannia.
The designer's website: http://www.pulsipher.net/britannia/index.htm
The rules: http://www.pulsipher.net/britannia/britanniafaq.pdf
The designer's blog: http://pulsiphergamedesign.blogspot.com/
I have just finished 'Collapse: How Societies choose to fail or succeed' by Jared Diamond and 'The March Up: Taking Baghdad with the United States Marines' by Bing West and Ray Smith, 'V for Vendetta' by Alan Moore and David Lloyd* and 'Modesty Blaise: The Puppet Master' by Peter O'Donnell and Enric Badia Romero* and a title on a German artillery unit of World War II earlier this week.
I am currently reading 'Illicit: How Smugglers, Traffickers and Copycats are hijacking the Global Economy' by Moises Naim, the editor of Foreign Policy, 'In the Company of Soldiers: A Chronicle of Combat' by Rick Atkinson, 'Self-Discovery' by Vladimir Savchenko, and a couple of others.
What are you reading at this moment?
*The artist of that respective comic.
More images of Nanjing Road. I took them when I was in Shanghai a month or so ago. The glitter of the citylights. The multitudes on the streets at night. It's astonishing.
Singapore feels like a backwater compared to Shanghai. This is a world city, akin to London, Paris or New York.
There are huge bookstores like the seven-storey one along Nanjing Street. If only they carry books in English.
Strangely enough, as I typed this entry, a woman from Beijing called. She was from a government business bureau and she wanted to confirm my company's information. She was able to speak Mandarin and English well. How times have changed. If Mao Zedong were still alive, I wonder how he would have regarded the vast changes sweeping China. From a strict communist, 'egalitarian' state to a free-wheeling capitalist state.*
The New World building. Look at the Samsung sign there. Amazing.
*Of course, by many standards, it is still authoritarian.
23 April 2006
Today, I set off at a brisk pace at the track at Toa Payoh Stadium. I was able to maintain that punishing pace for about two to three rounds. I ran six rounds in thirty seconds less time than I did last week.
Afterwards, I continued with a slow four rounds. I'm dead beat.
My current statistics in DuneMud. Ranking: 69. The level cap was 49 a decade ago. It's 200 now. I need to raise my statistics to match my guild level.
These are photos from the vast silk and cloth market in Shanghai. I see many many foreigners here. Americans, Brits, and what have you? They were all over the place haggling with the clothiers specifying the various cuts and designs wanted. I saw an American young man speaking Mandarin in a monotone voice, haggling over bales of silk. (He can't quite master the pronunciation of Mandarin as it is a tonal language. He reminded me of those corny Cylons in Battlestar Galactica.)
Yes, it was freezing cloth. The complex is a various labyrinthine place. Corridors upon corridors of such shops. I was staggered.
It's unbelievable. One has to see it to believe it.


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On January 13, ten students and two Campus Ministry staff members flew to Lima, Peru for a social justice immersion trip. Leaving the frozen Minnesota tundra for warm, sunny Peru may sound like a vacation for many, but this group did not waste any time lounging. They stayed in four different cities over 17 days where they explored diversity, joined in social justice work with the Sisters of St. Joseph and learned about the impacts of history on society and culture. Sam Kelly, Campus Minister for Social Justice, said, "We had a lot of goals for this trip but the main purpose was to connect the social justice issues students saw in Peru to their faith lives. We wanted to help students think about social justice and faith in a different way, by bringing them to a different place and exposing them to justice issues that were different but have similarities to justice issues in the United States."
The first city they visited was Lima, Peru's capital, where they spent four days with the CSJ's, who live and work in an area of Lima called Canto Chico. Continue Reading →


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100m vertical done, 3900m more to go (Volcán San José)
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Starting the long way up the summit to Volcán San José, which rises in the background (main summit in clouds). From the start in Lo Valdes (1850m) you need to cover 4000 vertical meters to the summit (5856m).
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Object Title: 100m vertical done, 3900m more to go (Volcán San José)


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Amon Amarth
Available immediately, Swedish heavy metal titans Amon Amarth - in partnership with Swedish video game developer and publisher Ride and Crash Games AB - has unleashed a new Amon Amarth mobile video game!Read More
Dimebag Darrell
Time for another sneak peek in advance of this Friday's release! Today, Revolver presents an additional exclusive trailer for 'Dimevision Vol 2: Roll With It Or Get Rolled Over', giving fans an insider's look at the upcoming video.Read More
Mother Feather
Currently finishing work on their sophomore album with Grammy-nominated producer Joshua Valleau, Mother Feather has launched a new lyric video for the track 'Egyptology.'Read More
Fates Warning
On January 12th, Metal Blade Records will re-issue two of Fates Warning's fan-favorite albums, 'Perfect Symmetry' (1989) and 'Parallels' (1991), as part of the label's 'Originals series'.Read More
Cannibal Corpse
Cannibal Corpse recently released their new album, 'Red Before Black', via Metal Blade Records; for their efforts, the band has now entered the international charts!Read More
New Releases
Upcoming Releases
Latest News
Revocation premieres lyric video for "Crumbling Imperium" via Loudwire.com
- June 23rd, 2016 – On July 22nd, Revocation will release their most...Read More
Hammers of Misfortune premieres new track, "Sea of Heroes", via Stereogum.com
- June 23rd, 2016 – On July 22nd, West Coast progressive heavy...Read More
Byzantine to play select USA shows this summer, starting tomorrow
- June 23rd, 2016 – New video for "Justinian Code" launched...Read More
Denner / Shermann releases video for new track, "Son of Satan", taken from their upcoming album, 'Masters of Evil', out June 24th
- June 22nd, 2016 – Denner / Shermann has released a new video for the...Read More
Necromancing the Stone declares war on "Breakdownicus Gratuitous" with new album, "Jewel of the Vile"
- June 22nd, 2016 – Launches first single, "The Siren's...Read More
Denner / Shermann launches trailer for upcoming video, "Son of Satan"
- June 15th, 2016 – The trailer for the long-awaited music video,...Read More
Whitechapel streams new album, 'Mark of the Blade', via VansWarpedTour.com
- June 13th, 2016 – Launches social media takeover of Vans Warped Tour...Read More
Ketzer releases official live videos for "When Milk Runs Dry" and "Starless"
- June 13th, 2016 – German extreme metallers Ketzer recently returned...Read More


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The incredible life of my new sister, Juliet, and me, Roxy Dragon Pebbles, otherwise known as The Devil Dog. I have no idea what I did to deserve that name! Honest! Just because I'm a black dog doesn't mean I'm naughty dog.
Nice tongues girls.You can use them to give Old Man Winter a raspberry!Purrs Georgia and Julie,Treasure and JJ
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text:
MOVIE SYNOPSIS [ General Audiences ] Feature film of Saeed Khoze. Its premiere was performed in 2012, it is a production of USA. You can watch Keep the Flight in Mind online on TV cable or theaters with original audio in English at different dates. This film premiered in theaters in 2012.
Rating: 5 by 64 users./
Runtime: 100 minutes
Behrouz Vossoughi.
Documental, Biographic.
100-minute film (full movie) directed by Saeed Khoze.
The original audio of Keep the Flight in Mind has dialogues in Dolby Digital, it was produced in USA.
It premiered in cinemas or television in 2012.
Screenplay written by Saeed Khoze.
Afshin Sosidar, Houshang Baharlou, Donald Martin, Maziyar Parto and Nemat Haghighi.
Saeed Khoze.
This film was produced and / or financed by LA Independent Film & Entertainment L.I.F.E..
Composed by Houman Pourmehdi, Sean Paxton and Esfandiar Monfaredzadeh.
LA Independent Film & Entertainment L.I.F.E..
Without commercial breaks, the full movie Keep the Flight in Mind has a duration of 100 minutes; the official trailer can be watched in streaming on the Internet. You can watch this full movie free in EnglishDolby Digital in movie TV channels, renting the DVD or with VoD services (Video On Demand player, Hulu) and PPV (Pay Per View, Netflix).
See the page of this full movie, Keep the Flight in Mind in FULLTV Movies.


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What an AWESOME day at the Brim! The conditions were great and the sun was shining brightly...spring skiing at it's finest!We still have LOADS of snow left on the slopes and the days in the season are winding down so don't miss out, join us tomorrow for some "down" time.All photos were taken TODAY March 19th 2011 at BRIMACOMBE!The freestyle skiers and snowboarders were throwin' down hard in today's BIG AIR competition. I'll most more pictures and the results tomorrow, but here are a few to tide you over...REMAINING HOURS OF OPERATION FOR THE 2010/11 SEASONSpring may be in the air, but there's still time to enjoy the snow at Brimacombe!Brimacombe will be open as follows, for the remainder of the season:Sunday, March 20 9:00 a.m. to 4:30 p.m.Wednesday, March 23 9:00 a.m. to 10:00 p.m.Saturday, March 26 9:00 a.m. to 4:30 p.m.Sunday, March 27 9:00 a.m. to 4:30 p.m.Beginning Wed, Mar. 23, enjoy reduced full-day lift ticket rates!? Adults/Students $35? 13 & Under $31? 5 years & under $5 (when accompanied by a paying adult)On March 23, 26 & 27, Brimacombe will operate the Standard Chair, Magic Carpet and Bowl Chair only. No trails west of Flyer will be open.* All night passes will be accepted on the evening of Wednesday, March 23.All dates are, of course, weather dependant.Always check our website, or call the snowline (905-983-7669) before heading out! ***THE EVENT YOU HAVE ALL BEEN WAITING FOR IS FAST APPROACHING!Immediately following the Puddle Jump we are proud to announce a FREE CONCERT featuring local rising stars ELEVEN PAST ONE!The rock-pop band from Bowmanville, Ont., formed in early 2007. Brothers Daniel Richter, Stephen Richter, and Joey Richter, along with Steve Patenaude and Nathan Meima, have performed in Canada and toured throughout the United States performing their debut album, The Ultimate Catch.Join us as we say good-bye to another FANTASTIC season at the Brim.It was another day in Paradise, Cheers,Mark
published by Brimacombe


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Nearly half of Operation Enduring Freedom / Operation Iraqi Freedom (OEF/OIF) veterans experience continued pain post-deployment. Several investigations report analgesic effects of allopregnanolone and other neurosteroids in animal models, but few data are currently available focusing on neurosteroids in clinical populations. Allopregnanolone positively modulates GABAA receptors and demonstrates pronounced analgesic and anxiolytic effects in rodents, yet studies examining the relationship between pain and allopregnanolone in humans are limited. We thus hypothesized that endogenous allopregnanolone and other neurosteroid levels may be negatively correlated with self-reported pain symptoms in humans.
We determined serum neurosteroid levels by gas chromatography / mass spectrometry (allopregnanolone, pregnenolone) or radioimmunoassay (dehydroepiandrosterone [DHEA], progesterone, DHEA sulfate [DHEAS]) in 90 male veterans who served in the U.S. military after September 11, 2001. Self-reported pain symptoms were assessed in four areas (low back pain, chest pain, muscle soreness, headache). Stepwise linear regression analyses were conducted to investigate the relationship between pain assessments and neurosteroids, with the inclusion of smoking, alcohol use, age, and history of traumatic brain injury as covariates.
Durham VA Medical Center.
Allopregnanolone levels were inversely associated with low back pain (p=0.044) and chest pain (p=0.013), and DHEA levels were inversely associated with muscle soreness (p=0.024). DHEAS levels were positively associated with chest pain (p=0.001). Additionally, there was a positive association between traumatic brain injury and muscle soreness (p=0.002).
Neurosteroids may be relevant to the pathophysiology of self-reported pain symptoms in this veteran cohort, and could represent future pharmacological targets for pain disorders.
More than 1.64 million military personnel have served during Operation Enduring Freedom / Operation Iraqi Freedom (OEF/OIF) to date (1). OEF/OIF deployments can involve high levels of combat stress, and many soldiers serve multiple tours of duty (2–4, 1); greater than one fourth of these returning veterans receive mental health or psychosocial diagnoses (5, 1). An even greater proportion (nearly half) of these returning veterans report persistent pain (6), and chronic widespread pain is a frequent occurrence in otherwise healthy OEF/OIF veterans (7). As a higher percentage of wounded military personnel fortunately now survive than ever before (2, 3), reduction and alleviation of pain in this cohort is an acute need. The amelioration of persistent pain symptoms via supplementation or modulation of endogenous compounds with analgesic actions may represent a promising treatment strategy, and neurosteroids represent potential candidates for this indication.
The neurosteroid allopregnanolone, a metabolite of progesterone, positively modulates inhibitory γ-aminobutyric acid type A (GABAA) receptors (8, 9). Other neurosteroids, including the sulfated metabolites of pregnenolone and dehydroepiandrosterone (DHEA), exhibit the opposite profile of GABAA receptor action (10–14). Extensive data demonstrate that various neurosteroids with positive GABAA receptor-modulating activities exert anxiolytic (15–18), anticonvulsant (19–23), and anti-aggression effects (24, 25), but additional evidence indicates roles for neurosteroids in analgesia as well (26–31). Given that GABAA receptors are integral to nociceptive processing (32–34), neurosteroids may play a significant role in the pathophysiology of pain.
The predominance of studies demonstrating analgesic neurosteroid effects reports the importance of allopregnanolone in preclinical pain models. Allopregnanolone increases response latencies to thermal stimuli in both rats (26) and invertebrates (30), increases response latencies to tailflick in rats (28), and protects against noxious mechanical visceral stimuli in rats (27). Allopregnanolone also may be responsible for the analgesic effects of its precursor progesterone, as multiple reports indicate that allopregnanolone is the active metabolite responsible for the anesthetic actions of progesterone (35, 29). It is presently unclear whether other neurosteroids modulate analgesic responses in rodents, as examination of dehydroepiandrosterone sulfate (DHEAS) reveals lack of analgesic effect (28), and studies examining pregnenolone sulfate differ, demonstrating both attenuation of capsaicin-induced nociception (36, 37) and failure to increase tailflick response latency in rats (28).
Compared to the number of studies investigating neurosteroids and pain in animal models, few studies in humans have been performed. Additionally, study findings to date have not been in complete agreement. For example, while endogenous DHEAS levels are no different between men with chronic osteoarthritis pain and pain-free controls (38), endogenous DHEAS levels inversely correlate with musculoskeletal pain in women during menopause transition (39). Further, supplementation with DHEA does not improve pain in postmenopausal women with fibromyalgia (40), but it does improve joint pain in aging men with partial androgen deficiency (41). The single investigation examining the relationship between allopregnanolone and pain in humans suggests that elevated endogenous allopregnanolone levels are associated with decreased pain tolerance in non-Hispanic white individuals but not in African Americans (42). Thus, additional clinical studies are needed to clarify the role of neurosteroids in human nociception.
This study therefore examined possible neurosteroid associations with self-reported pain measures as assessed by four questions of the Symptom Checklist-90-R [SCL-90-R; (43)] instrument in males who served in the military after September 11, 2001. The neurosteroids measured were allopregnanolone, pregnenolone, progesterone, DHEA, and DHEAS, and the four SCL-90-R items evaluated low back pain, chest pain, muscle soreness, and headache. Based on the prior animal literature and multiple reports in humans that synthetic steroid anesthetics structurally similar to allopregnanolone produce analgesic effects (44–47), we hypothesized that endogenous serum allopregnanolone levels would be negatively associated with self-reported pain.
All participants provided written informed consent, and the protocol was approved by the local institutional review board. The first 90 male subjects recruited into the VA Mid-Atlantic MIRECC Registry having a blood draw between 10:30 AM and 2:30 PM were included in this investigation. These 90 male subjects were enrolled between June 2005 and April 2006 at the Durham VA site. All participants in this Registry served in the U.S. military after September 11, 2001. Of the 82 veterans in this cohort with no missing data, 40 had served in the Army, 7 in the Navy, 12 in the Marines, 4 in the Air Force, 12 in the National Guard, 4 in the Reserves, 1 in both the Army and Marines, 1 in both the Air Force and the Marines, and 1 in both the National Guard and the Reserves. Of the 65 veterans who had served in the Army, Navy, Marines, or Air Force, approximately half (n=33) had also served in the National Guard and/or Reserves. At least 79 of the 82 veterans in this cohort served in a warzone (information not available for 3 veterans), with 36 of those 79 being combat veterans, 33 serving in combat support roles, and 10 providing warzone service support. Two veterans were receiving opioids (oxycodone/acetaminophen) for pain at the time of the evaluation, 5 were receiving non-steroidal anti-inflammatory agents, 1 was taking acetaminophen, and 1 was taking aspirin.
Subjects completed the SCL-90-R, which asked them to rate severity of symptoms over the past 7 days and included four items assessing pain: low back pain, chest pain, muscle soreness, and headache (43, 48). Each pain condition was rated with five possible response options: none at all (level 0), a little (level 1), moderate pain (level 2), quite a bit (level 3), and extreme (level 4).
Pregnenolone and allopregnanolone levels in serum were determined by a highly sensitive and specific gas chromatography/mass spectrometry (GC/MS) method in the negative ion chemical ionization mode, as previously described (49, 50). One mL of serum was extracted three times in ethyl acetate prior to high-performance liquid chromatography (HPLC) purification utilizing tetrahydrofuran, ethanol, and hexane in the mobile phase. A subset of samples (30%) was injected in duplicate. The mean coefficients of variation for pregnenolone and allopregnanolone in this subset were 1.9% and 6.8%, respectively. The limit of detection with this method was 2 picograms for both pregnenolone and allopregnanolone. Other serum steroid levels were determined utilizing commercially available radioimmunoassay (RIA) kits according to manufacturer directions (progesterone and DHEAS: Diagnostic System Laboratories, Webster, TX). DHEA serum levels were determined utilizing a kit from ICN Pharmaceuticals (Costa Mesa, CA).
In this exploratory investigation, four stepwise linear regression analyses utilizing SAS software (SAS Version 9.1, Cary, NC) were performed examining possible relationships between neurosteroid levels (predictor variables) and pain ratings (response variables) (i.e. ratings of low back pain, chest pain, muscle soreness, and headache reported on the SCL-90-R). Several factors that potentially affect both neurosteroid levels and psychiatric symptoms (age, smoking status, alcohol use, and history of traumatic brain injury (TBI; defined as a past TBI with loss of consciousness by self-report; modified from Ivins et al and Kay et al (51, 52)) were included as covariates in the regression analyses. SAS default mode p<0.15 was used for terms entering or leaving the stepwise linear regression models in this pilot study.
Table 1 summarizes the demographic and clinical data for this study sample. Of 90 male veterans who served since September 11, 2008 and who were enrolled at the Durham VA site, 82 subjects had no missing data. Subject mean age was 37.3 ± 10.3 SD years. Forty-eight percent were African American, 46% Caucasian, 4% Hispanic, and 2% Native American. Fifteen percent (12/82) of the sample reported a history of TBI with loss of consciousness (LOC). Of these 12 veterans, 9 sustained one TBI with LOC and 3 veterans sustained two TBIs, both with LOC. Of the 15 total TBIs with LOC, estimated duration of LOC by self-report was 1–20 minutes for 11 TBIs, 21–59 minutes for 1 TBI, 60 minutes or greater for 2 TBIs, and an unknown period of LOC for 1 TBI. Seventy-six percent were non-smokers (either never smoked or had quit). The average alcohol use score on the Alcohol Use Disorders Identification Test [AUDIT; (53)] was 6.2 ± 6.6 (SD).
In the stepwise linear regression model, there was a significant, inverse relationship between allopregnanolone levels in serum and ratings of back pain (Table 2; p=0.044). Allopregnanolone levels in serum are higher in subjects reporting a 0 or 1 for low back pain severity (no/little pain) compared to those reporting a 2, 3, or 4 for low back pain severity (moderate to extreme pain) on the SCL-90-R (mean levels 102.5 ± 58.9 SD pg/ml vs. 81.1 ± 34.3 SD pg/ml, respectively; n=42 for no/little pain group and n=40 for moderate-to-extreme pain group). Allopregnanolone levels in serum also were significantly, inversely related to ratings of chest pain in this model (Table 2; p=0.013); allopregnanolone levels in serum are higher in subjects reporting a 0 or 1 for chest pain severity compared to those reporting a 2, 3, or 4 for chest pain severity on the SCL-90-R (mean levels 97.9 ± 52.0 SD pg/ml vs. 67.9 ± 25.7 SD pg/ml, respectively; n=66 for no/little pain group and n=16 for moderate-to-extreme pain group). Thus, participants who had lower levels of serum allopregnanolone reported higher levels of back pain and chest pain. Serum allopregnanolone levels were not significantly related to ratings of headache and muscle soreness (data not shown).
Stepwise linear regression analyses were also used to examine the relationship of pregnenolone, DHEA, DHEAS, and progesterone levels to pain ratings. These analyses revealed two additional, significant relationships between neurosteroids and pain ratings. First, DHEA levels in serum were inversely related to ratings of muscle soreness (Table 2; p=0.024). DHEA levels in serum are higher in subjects reporting a 0 or 1 for muscle soreness severity compared to those reporting a 2, 3, or 4 for muscle soreness severity on the SCL-90-R (mean levels 10.8 ± 6.2 SD ng/ml vs. 8.8 ± 4.6 SD ng/ml, respectively; n=54 for no/little pain group and n=28 for moderate-to-severe pain group). Second, DHEAS levels were positively related to ratings of chest pain (Table 2; p=0.001). DHEAS levels are lower in subjects reporting a 0 or 1 for chest pain severity compared to those reporting a 2, 3, or 4 for chest pain severity on the SCL-90-R (mean levels 243.9 ± 145.5 SD μg/dl vs. 299.9 ± 188.6 SD μg/dl, respectively; n=66 for no/little pain group and n=16 for moderate to extreme pain group).
As noted above, we included several demographic and clinical variables as covariates in the stepwise regression analyses predicting pain ratings: age, smoking, alcohol use, and history of TBI. None of these covariates were found to be correlated with pain ratings, with the exception of a positive association between TBI and ratings of muscle soreness (Table 2; p=0.002).
Consistent with our hypothesis, the present study demonstrates an inverse association between serum allopregnanolone and ratings of low back pain and chest pain in subjects who served in the U.S. military since September 11, 2001. These data support the possibility that there may be antinociceptive effects for this neurosteroid in humans. Future studies are needed to replicate these findings and to definitively evaluate the precise roles of allopregnanolone in pain disorders. Also, the finding that DHEA demonstrates an inverse association with a pain measure (muscle soreness) in this cohort raises the possibility of a more general antinociceptive feature for neurosteroids as a class.
To date, the existing literature contains few studies examining the relationship between neurosteroid levels and pain in clinical populations. When the field is narrowed further to only allopregnanolone, a neurosteroid with considerable evidence of analgesic properties in rodents (26, 35, 27–31), only one human study remains and this was conducted in a pain-free healthy volunteer cohort rather than a population that included subjects with pain symptoms (42). This previous study reported that individuals who showed higher endogenous allopregnanolone levels in response to cold pressor, thermal heat, or tourniquet ischemia pain tests were less likely to report an increase in pain tolerance. In addition, this study reported that baseline allopregnanolone levels correlated significantly with a decrease in pain tolerance during pain testing in one ethnic group in the study sample (i.e., non-Hispanic whites).
Several experimental differences from the present study, however, should be noted when comparing the findings of the Mechlin et al. and the current study. Perhaps most importantly, these studies may involve different pathophysiological mechanisms, as the present study examines correlations in baseline perceived pain levels, whereas the study by Mechlin et al. examines effects on pain threshold and tolerance via several acute stressor paradigms. Whereas the present study included a clinical population reporting pain complaints, the Mechlin et al. study focused on healthy volunteers free of chronic pain conditions. Further, while the present study included only males, Mechlin et al. included both males and females, thereby potentially influencing mean baseline allopregnanolone levels since this neurosteroid fluctuates across the menstrual cycle (54–56). This point may be especially relevant in light of the fact that the reported pain tolerances were gender specific in the previous study (42). Methodologically, it also should be noted that Mechlin et al. determined allopregnanolone levels via radioimmunoassay, a technique that may identify several GABAergic neurosteroids simultaneously based on an 84–169% cross-reactivity of the method with 3α-hydroxy-4-pregnen-20-one (55, 57) and 6.6% cross-reactivity with pregnanolone (55), potentially also contributing to divergent results.
While the present study finds that higher endogenous allopregnanolone levels correlate with decreased reporting of some types of pain symptoms, the mechanisms responsible for potential analgesic effects of this neurosteroid remain to be determined. Some possible explanations are currently supported in the literature, including a role for allopregnanolone in anti-inflammatory actions. For example, in both mice and rats, allopregnanolone administration reduces levels of inflammatory cytokines (58, 59). Longer term, the effects of allopregnanolone may result from protection against cell degeneration and/or cell death, as considerable evidence exists implicating allopregnanolone in several neuroprotective actions. For example, in a mouse model of the fatal, autosomal recessive neurodegenerative Niemann-Pick type C disease, there is a substantial reduction in the synthesis of allopregnanolone at birth (60), and neonatal administration of allopregnanolone delays neurological symptom onset and doubles lifespan (61, 62). Further, neonatal administration of allopregnanolone increases neuronal myelination (62), a process previously demonstrated to involve GABAA receptors (63). Also, allopregnanolone inhibits apoptosis in rat models of TBI, decreasing caspase-3 activity and DNA fragmentation (64), decreasing glial fibrillary acid protein-positive astrocytes, and improving performance in spatial learning tasks (65). Multiple mechanisms may thus contribute to a possible analgesic and neuroprotective effects of this neurosteroid in humans.
Examination of additional neurosteroids yielded no association of either pregnenolone or progesterone with any of the pain measures, but findings did emerge for both DHEA and DHEAS. While we found that DHEA levels in serum were inversely associated with muscle soreness, levels of its sulfated form were positively associated with chest pain. Prior evidence has yielded inconsistent analgesic profiles for both DHEA and DHEAS (39, 41, 40, 38) in humans. However, the differences in findings for each of these neurosteroids have been between inverse correlations with pain vs. no correlations at all. Thus, the positive correlation between DHEAS and chest pain in the present study is surprising both in that the response differs from that of DHEA, and in its incongruity with previous studies. Why these two neurosteroids demonstrate opposite serum profiles vis-a-vis pain ratings in this subject population is not yet clear. Further examination of various pain types and severities is needed to determine whether these findings are specific to muscle soreness or chest pain, as most previous studies reporting no correlation or a negative correlation for DHEAS have examined other types of pain (e.g., joint pain). Also, an examination of the same neurosteroids and pain measures in women could provide important information about possible gender-specific associations, as a negative correlation between DHEAS and musculoskeletal pain has been reported in a subject population of 57 women undergoing the menopausal transition (39).
Finally, while age, current smoking, and history of alcohol use are not associated with any of the pain measures in the present study, a history of TBI is associated with muscle soreness. This association is not a surprising one (66–69), especially given the high rates of polytrauma in this cohort of returning veterans (70, 4, 71). However, the lack of an association with other pain measures such as headache is unexpected. It is possible that a larger sample size or the use of a more comprehensive pain assessment may be required to capture these additional associations.
Limitations of this exploratory pilot study must be acknowledged. Our R2 values were relatively low, with a maximum result of 0.17. We also conducted four separate analyses, thereby potentially increasing the likelihood of Type I error. Nevertheless, with the exception of TBI, only neurosteroid variables were significant in our analyses, supporting our hypothesis for a neurosteroid role in pain modulation. Further, the instrument utilized does not query the specific type of headache, potentially limiting assessments of relationships between neurosteroid levels or other findings and headache. Results will clearly require replication in a larger cohort, but these initial findings are promising, as they are consistent with the preclinical literature and provide data for future hypothesis testing.
In summary, the present study demonstrates that increased levels of endogenous allopregnanolone are associated with decreased self-reported low back pain and chest pain in subjects who served in the U.S. military after September 11, 2001. In addition, increased levels of DHEA are associated with decreased muscle soreness pain, and higher DHEAS levels are associated with increased chest pain in this population. This analysis used exploratory techniques (stepwise linear regression) and results should be replicated in an independent sample. These findings, particularly if supported by future replication studies, suggest that modulation of allopregnanolone or other neurosteroid levels may be logical targets for therapeutic intervention in pain disorders.
This work was supported by the following sources: VA Mid-Atlantic MIRECC, K23 MH 65080 (CEM), VA Advanced Research Career Development Award (CEM), VA Career Development Award (JLS). Dr. Marx discloses that she is a co-applicant on pending U.S. patent applications on the use of neurosteroids and derivatives for the treatment of central nervous system disorders and for lowering cholesterol, and she is an unpaid scientific advisor and unpaid board member of NeuroScience Pharmaceuticals. The remaining authors have no potential conflicts of interest to disclose. The views expressed in this presentation are those of the authors and do not necessarily represent the views of the Department of Veterans Affairs or the National Institutes of Health.
PubMed Central Canada is a service of the Canadian Institutes of Health Research (CIHR) working in partnership with the National Research Council's national science library in cooperation with the National Center for Biotechnology Information at the U.S. National Library of Medicine(NCBI/NLM). It includes content provided to the PubMed Central International archive by participating publishers.


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1,100+ high-yield facts based on student reporting from the 2010 exam
Hundreds of clinical images, including a 24-page full-color insert
Student ratings of top review books
Updated information throughout
High-yield facts organized into basic principles and organ system sections facilitates study
Use with First Aid Cases for the USMLE Step 1 and First Aid Q&A for the USMLE Step 1 to create the ultimate Step 1 review package


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LAST month Emilie Cole became an editor. Sort of. The 28-year-old San Franciscan tech executive spotted a couple of story ideas she liked on a website and paid for journalists to start working on them. And all for the princely sum of $40 (€27) in total. Cole is one of a growing band of people supporting community-funded journalism in a city reeling from the impact of the web on its traditional news outlets.
Spot.Us – Community Funded Reporting Intro from Digidave on Vimeo.
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The stories that caught Cole's eye were on www.spot.us, a community journalism site. Now operating in San Francisco and Los Angeles, spot.us solicits ideas for investigative articles from journalists and then asks its readers for the money to pay for the reporting.
Cole gave $20 to a story that will look at illegal immigrant students and their chances of earning permanent residency in America. So far that story has raised $328 and is looking for another $672.
TRENDING: Matador's Crotch Takes Bull by the Horns in Gruesome Video
She's also pitched in $20 to fund reporting on local police in San Francisco and Oakland, as well as the court system.
Read More: By Dominic Rushe, UK Times
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Moke takes the mainstream and puts it through a prism. The slick sound of "now" is apparent, but it's shot through with an indie edge and a classic rock vibe. The paradoxical music is both condensed and sprawling, stomping and delicate. The band sounds proud and self-confident, with plenty of young-buck swagger, yet at the same time it's beautifully flawed in its humanity.
Moke vocalist John Hogg strikes a similar balance in his lyrics. A somewhat jaundiced worldview is balanced by the sense that on a day-to-day basis it's all going to work out anyway. Hogg is articulate to a degree seldom found in current straight-ahead rock music (which, after all, is what Moke is) but never becomes too clever for his own good. From the bravado of "My Degeneration" to the contemplative acoustics of "Slide" -- "Warriors are wagers / Sinners are our saviors / Excuse me while I slip into something more insulting / These are the pleas of the pale in power" -- the attentive listener is almost always stimulated, but never annoyed.
In support of its debut CD, the London-based quartet traveled the United States with both the Black Crowes and the Goo Goo Dolls. In fact, four years of arduous touring took the band to all five continents and honed Moke's already energetic live performances. It also provided Hogg with the lyrical fodder to create what he calls "an expression of spirituality, without all the details."
Fitzgerald's, 2706 White Oak Drive
Saturday, November 24; 713-862-3838
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Now touring in support of its sophmore effort, Carnival, Moke is in tow behind King's X. It's as easy to imagine Moke at home on a bill with the native Houstonians as it is to imagine the group with the Goo Goo Dolls. The underpinnings of rock are every bit as evident in this outfit as its pop sensibilities.


text: I just bought my first Android phone, a Moment. I downloaded my first paid app today which was easy tether. Does the android market remember what paid apps I bought in case I ever have to wipe my phone or switch phones? If so, how does this work? Thanks for the responses!


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1 - 4 Final
Preds win again in battle for No. 4 seedApr 9, 2011 - 5:21 AM
Wins by Nashville and Phoenix on Friday gave both teams 99 points for the fourth spot in the Western Conference with one game to play. The Predators play in St. Louis while Phoenix plays in San Jose with both games on Saturday.
Patric Hornqvist scored twice and added an assist while Matt Halischuk and Sergei Kostitsyn each had a goal for the Predators, who have won two straight and close out their season on Saturday in St. Louis.
Derick Brassard had the lone goal while Steve Mason was touched for all four goals on 25 shots for the Blue Jackets, who have dropped their past five games.
"When you have a good goaltender like they do it forces you to shoot more," said Brassard. "There is a lot of frustration in our locker room cause we try hard and put everything we have into every game and it's just not working out for us right now."
Six minutes into the game the Predators took a 1-0 lead as Mike Fisher took the puck into the Columbus end and outhustled the defender to get a shot on net down low that Hornqvist followed up for the rebound goal.
Less than two minutes into the second, the Predators took a 2-0 lead as Halischuk took a pass in the Columbus end and switched to the forehand before stuffing the puck in.
It was a 3-0 game less than a minute later as Hornqvist's backhander from the right circle fooled Mason for his 21st goal of the season.
Brassard got Columbus on the board with 1:28 to play in the second with a big blast from the right circle that beat Rinne cleanly.
Kostitsyin scored with 7 1/2 minutes to play in the third with a tip-in of a Hornqvist pass.
Game Notes
Nashville went 24-9-8 at home this season...The Blue Jackets, who were 17-16-8 on the road, close their season at home on Saturday against Buffalo...The Predators took four of six from Columbus this season.
- 20
rootsMattDOOM777 Added 5 roots
Blue Jackets 1, Predators 4 FinalApr 11 11:29 AM
Apr 8 10:34 PM
- Nashville Goal - Sergei Kostitsyn (23), from Patric Hornqvist and Kevin Klein at 12:25.
Blue Jackets 1, Predators 4 3rd - 7:35Apr 8 10:19 PM
End of 2nd
Apr 8 9:44 PM
- Columbus Goal - Derick Brassard (17), at 18:32.
Blue Jackets 1, Predators 3 2nd - 1:28Apr 8 9:41 PM
- Nashville Goal - Patric Hornqvist (21), at 2:42.
Blue Jackets 0, Predators 3 2nd - 17:18Apr 8 9:11 PM
- Nashville Goal - Matt Halischuk (4), at 1:48.
Blue Jackets 0, Predators 2 2nd - 18:12Apr 8 9:09 PM
End of 1st
Apr 8 8:49 PM
- Marc Methot shot blocked by Kevin Klein.
Blue Jackets 0, Predators 1 1st - 13:01Apr 8 8:25 PM
1st Period - 20:00
Apr 8 8:08 PM
- 15
rootsRUWTbot Added 15 roots
Blue Jackets vs. PredatorsJun 23 6:03 AM
Related News
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- Werenski scores in OT, Blue Jackets beat Canadiens 2-1 Wed
- Filip Forsberg lifts Predators past Penguins 5-4 in SO Nov 12
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- NHL Note - Nashville Predators Jarnkrok, Calle Nov 8
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- NHL Note - Columbus Blue Jackets Dubois, Pierre-Luc Nov 8
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- NHL Note - Columbus Blue Jackets Atkinson, Cam Nov 8


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- Please select a date to see the proper prices!
- Meal can be requested on the spot
Best offer
144 € / person / night, no meal
Description of the accommodation:
Rooms, services Take a visit to Austria, either for a nice weekend or a longer holiday, and book a room at Arthotel Blaue Gans Salzburg. The hotel is welcoming all guests in Salzburg with 35 comfortable rooms to stay in. You may taste delicious, fresh meals in the restaurant of the hotel every day. Car parking possibility is available nearby. You may take an organized city tour to check the most important tourist attractions. Bike rental, bowling, water ski, volleyball, diving, sailing, surfing, boat rental and ballontrip opportunities will also be available nearby to help you spend your leisure time actively. Airport transfer is available upon preliminary request. The café and the bar provide a nice atmosphere for a romantic evening talk or a personal meeting. In the safe your valuables can be the safely secured. Wireless Internet connection (WiFi) is available at the hotel, enabling portable devices and smartphones to go online. You can find the exact list of services provided by Arthotel Blaue Gans Salzburg (including those for extra fees) and the exact equipment of the rooms on the information sheet below.
Payment Advance payment by credit card or providing credit card guarantee may be necessary for finalizing the reservation, depending on the chosen date, room and price.
Arrival, opening hours The earliest time to check in at the hotel is 15:00, the latest time to check out is 11:00. The personnel of the hotel can speak in English and German with you.
Arthotel Blaue Gans Salzburg rooms Rooms
- Please select a date to see the proper prices!
Accommodation services
Parking (14 €/night)
Free WiFi in shared places
Relaxation: Squash, Bowling, Bike rental at the accommodation
Organized sightseeing nearby, Water skiing nearby, Volleyball facility nearby, Scuba diving nearby, Sailing nearby, Surfing nearby, Boat rental nearby, Hot air balloon nearby
Default services: Pet friendly (25 €/night), Bar, Cafe, Elevator, Safe deposit box
Airport transfer
Own restaurant
Bathrobe, Hairdryer, Desk in the room, Mini-bar


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PRAGUE, Oct 23 (Reuters) The United States has proposed keeping parts of its missile defence shield on ''stand-by'' short of full readiness in a bid to soothe Russian concerns, US officials and NATO envoys said today.
Under the proposal, the shield would be fully activated only when a threat emerged. Key to any progress on the idea would be Moscow and Washington overcoming divergences over the imminence of the threat from a state such as Iran, officials said.
''The difference is over timelines, how soon the ballistic missiles with a range that could reach the United States or greater parts of Europe can be achieved,'' a senior US government official told Reuters.
''The Russians say later rather than sooner. We say sooner rather than later,'' said the official, who was speaking on condition of anonymity, of estimates on the state of Tehran's missile programmes.
The United States plans to place interceptor missiles in Poland and a radar system in the Czech Republic as part of a shield Washington says is needed to counter possible attacks from ''rogue states'' including Iran and North Korea.
President Vladimir Putin mentioned last week US efforts to address concerns over a system which Moscow believes could target Russia, but did not refer to specific initiatives.
US Pentagon chief Robert Gates and US Secretary of State Condoleezza Rice brought proposals to Moscow earlier this month, but public attention focused on a separate move to allow Russian authorities to inspect the shield installations.
''The Russians were surprised and need time to think about it,'' said one NATO diplomat of the proposal to keep parts of the shield on stand-by.
FULLY OPERATIONAL Under the proposal, the system would be built to be fully operational but kept in a stand-by mode pending development of any threat.
The US official described the initiative as one of a number of ''high-concept proposals'' being left deliberately vague for now because of uncertainty over the Russian response.
''There are a variety of different steps, half-steps, half-measures that could be, might be, implemented if we actually are able to reach agreement with the Russians on the threat with Iran,'' the official said.
''So any idea of, you know, not activating the system -- any firm notion that we won't activate the system till we get Russian compliance isn't something that is so explicit.'' The West suspects Tehran of seeking the atom bomb and rejects its arguments that its nuclear programme is intended purely for generating electricity.
Gates is due to meet his Russian counterpart Anatoly Serdyukov at a meeting of NATO defence ministers on the Dutch coast on Wednesday and Thursday. Russia is routinely invited to such talks to try to further NATO-Russia cooperation.
The missile shield dispute has been one of several at the heart of a chilling of relations between Moscow and the West over the past year. Russia has said it may spark a new arms race and Putin has said he could re-deploy some of Russia's weapons if its concerns were not heeded.


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Mangaluru: The city crime bureau of the police on Jan 24 received a reliable tip-off that a group was involved in cricket-based betting. They raided a house in Chembugudde in Thokkottu where they operated from.
The betting was being conducted on the likely result of the Big Bash 20:20 cricket match being held in Sydney, Australia. Heavy amounts were being collected from the public and placed at stake.
During the raid, Rs 3,56,000 in cash, 13 mobile phones, a Sony LED TV and three diaries recording the collections and other notes were seized. Total value of the seized goods is Rs 4 lakh.
Three persons operating the ring were arrested. They are Alwyn Kiran Monteiro (32), Inas D'Souza (41) of Hoigegadde in Ullal and Gitesh (37) from Kuttar in Munnur.
The case and seized items have been handed over to the Ullal police for further action.


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Creativity and passion fuel every single design project we work on...
Web Design
As an increasing number of audiences are now spending their time using a multitude of different devices, and sometimes at the same time, it has never been as important as it is now to ensure your online communication has the right impact.
Your brand, marketing and wider communication is fighting with the likes of BBC iPlayer, YouTube, Instagram, Facebook and Twitter. How do you stand up against the big guys?
Who is your audience?
An average internet user now spends over 30 hours online each month, expecting compelling and engaging results on any device, no matter the size, brand or technology. Are you meeting their expectations?
As your users can move from site to site quicker than ever before it's become so important to ensure that your online communication loads quickly, is easy to use, reads well and has real visual impact.
How can we help?
Whether you have an established brand, a few colours and a logo or have no idea what you'd like at all, our designers all have the experience, knowledge and creativity to work and consult with you to tease out the information we need.
Paramount to the creation of our design work, is understanding who the end-user, your audience are; this will be in the form of research, a clear understanding you already have of your audience or through socio-economic profiling and demographics. With this information, we are able to ensure that we build bridges between you and your users via designs which are perfect for your audience.


text: Vivien grew up in Princeton, New Jersey (Yes! This Princeton, New Jersey!) and has enjoyed pretending to discover every off campus ice cream and sandwich shop she's really eaten at since she was five. She got into improv her senior year of high school and is thrilled to be a part of Quipfire!. Aside from making things up, she enjoys playing club field hockey, rolling her eyes, and choreographing elaborate dance numbers to the Pippin soundtrack.


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By entering you accept our Terms and Conditions and our Privacy and Cookies Policy. Hennessy encourages drinking responsibly. You must be of legal drinking age to enter.
- 2 oz Hennessy Black
- .5 oz fresh lemon juice
- 1/3rd oz Agave nectar
- 2 dashes Orange bitters (preferably Regan's No.6)
- Garnish: Orange twist
- Glass: Rocks glass
Method: Add all ingredients to a shaker tin with ice and shake until well chilled. Strain into a rocks glass over 1 large ice cube, and garnish with a orange twist.


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Unforgettable Movie Wiki
Unforgettable is an upcoming Hollywood thriller movie which is directed by Denise Di Novi and written by Christina Hodson and David Leslie Johnson. Unforgettable is produced by Denise Di Novi, Alison Greenspan and Ravi D. Mehta under the banner of DiNovi Pictures. On June 22, 2015, after director Asante and actresses Hudson and Washington had left the project, it was revealed that well known producer Di Novi would make her directorial debut with the film. Principal Photography on the movie began on August 17, 2015 in Los Angeles.
Stars Katherine Heigi and Rosario Dawson are playing lead roles in the movie. On December 2, 2014, Kate Hudson and Kerry Washington joined the lead cast of the film, about a man who is being threatened by his ex-wife. Katherine Heigi is playing role as 'Tessa Connover' and Rosario Dawson as 'Julia Banks'.
The movie is scheduled for release on April 21, 2017.
Unforgettable 2017 Movie – Poster
Lead Star Cast Of The Movie
Katherine Heigi and Rosario Dawson are playing lead roles in the movie. Katherine Heigi is playing role as 'Tessa Connover' and Rosario Dawson as 'Julia Banks'.
Official Trailer Of The Movie Unforgettable
Watch the official trailer of the movie.
Other Upcoming Movie Trailers: – Fifty Shades Darker, Annabelle 2 Full movie Details, The Mummy – Tom Cruise, Spider-Man: Homecoming, Guardians Of The Galaxy 2,……..
Other Details Of The Movie – Director to Producer!
|Denise Di Novi
|Frédéric Thoraval
|Caleb Deschanel
|Production Company
|DiNovi Pictures
Other Hollywood Upcoming Movies
- The Mummy – Tom Cruise
- Monster Truck
- Spider-Man: Homecoming,
- Guardians Of The Galaxy 2
- Baywatch – Dwayne The Rock Johnson
- John Wick 2
- Annabelle 2 Full movie Details


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On June 19 I was booked in to be induced due to elevated blood pressure and excessive swelling.
I attended hospital where gel was inserted at 5.15pm to soften the cervix. I was on the trace which showed good fetal heartbeat but no contractions. By 7.20pm I started losing bloody mucus. I was taken off the trace and moved to the ward. My mum arrived from Melbourne just after I was moved – she was my birth photographer.
By 1.45am, June 20, mild contractions had started. I used the shower to ease the pain which was primarily in my back. By 2.40am I was moved back to the birthing suite where another trace was done which showed the mild contractions. I had another shower and by 4am contractions had stopped intensifying.
At 7.45am my waters were broken by the obstetrician and I was 1cm dilated. At 8am the drip was started to progress the contractions. Contractions were more intense and more frequent.
At 9.30am I tried the gas and a Maxalon injection was also administered for nausea but a negative reaction to one of these sent me a bit loopy. I begged the midwife to allow me to shower for back pain and I was permitted 15 minutes in the shower while some pethidine was ordered. I was now 3-4cm dilated.
At 11.05 the pethidine was administered. It was from here that things progressed quickly. I sat on end of bed with the soles of my feet together rocking round and round, back and forward – similar to how you use the exercise ball. I was in a zone. I would grab onto my partner during contractions but otherwise I just rocked.
It was 11.35am when I started feeling the need to push and was struggling to not push through the contractions. The midwife Anna did an internal and said I was about 6cm dilated. I kept repeating the need to push so at 11.45 she checked again and said 9cm but that she wanted someone else to check. A second midwife checked at 11.50am and said I was fully dilated.
I wanted to be on all fours but I pushed through the first contraction on my back before moving. I pushed through next contractions on all fours and 20 minutes later – at 12.10pm – River arrived.
She was passed through my legs to me so I could discover her gender and I got to cuddle her while mum cut her cord. She was then given to my partner while I moved onto my back to deliver placenta. The OB arrived just after placenta delivered and checked me over sewing up a few areas.
River Elisabeth was a healthy 6lb4oz at birth. Length of 47cm. Head circumference of 33cm.
Thanks to mum Toni for sharing her incredible birth story with us.
Find out how you can submit your birth story!


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Vanmycetin T 0.3% Drop
FDC Ltd
Composition for Vanmycetin T 0.3% Drop
Prescription Required
Primarily used for
5 ml in 1 packet
Medicine Overview of Vanmycetin T Drop
Uses of Vanmycetin T Drop
Vanmycetin T 0.3% Drop is used in the treatment of bacterial infections.
Side effects of Vanmycetin T Drop
Nausea, Noisy breathing, Oral fungal infection, Rash, Thoracic pain, Chest pain, Chest tightness, Shortness of breath, Cough, Dizziness, Dry eye, Gastric pain, Fungal infection, Headache, Hearing loss, Coughing up blood, Liver toxicity, Hoarseness of voice, Increased saliva production, Loss of appetite, Mouth ulcer, Tongue ulcer, Ringing in ear, Sore throat, Weakness, Increased sputum production.
How to use Vanmycetin T Drop
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a marked dropper and take it as directed. It is better to take Vanmycetin T 0.3% Drop empty stomach (1 hour before food or 2 hours after food).
How Vanmycetin T Drop works
Vanmycetin t 0.3% drop is an antibiotic. It kills bacteria by inhibiting synthesis of essential proteins, required by bacteria to carry out vital functions.
In Depth Information on Vanmycetin T Drop
Expert advice for Vanmycetin T Drop
- Do not use tobramycin if you are allergic to it or any other component in the formulation.
- Driving and using machinery should be avoided in cases where tobramycin usage causes dizziness or eye drops cause blurring of vision.
- Do not mix or dilute your tobramycin with any other medicine in your nebulizer.
- If you are taking several different treatments for cystic fibrosis, you should take them in the following order: bronchodilator (e.g. salbutamol), then chest physiotherapy, followed by inhaled medicines, and then tobramycin.
- Do not use contact lenses when on treatment with tobramycin eye drops.
- If you are using more than one eye drop, keep a gap of at least 5-10 minutes between two different eye drops.
- Doctor's advice should be considered in case of patients with following history of disease conditions: neuromuscular disorders such as parkinsonism, myasthenia gravis (characterized by movement disorders and/or muscle weakness); coughing up blood in your sputum; kidney problem.
- Inform your doctor if you have ever experienced in the past: ringing in ears, any other problems with hearing, dizziness while taking tobramycin.
Special precautions for Vanmycetin T 0.3% Drop
Interaction with alcohol is unknown. Please consult your doctor.
Vanmycetin T 0.3% Drop is unsafe to use during pregnancy.+more
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor....
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Vanmycetin T 0.3% Drop is safe to use during lactation. Hum+more
an studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby....
Vanmycetin T 0.3% Drop does not usually affect your ability to drive.
Vanmycetin T 0.3% Drop should be used with caution in patien+more
ts with kidney disease. Dose adjustment of Vanmycetin T 0.3% Drop may be needed. Please consult your doctor....
There is limited information available on the use of Vanmyce+more
tin T 0.3% Drop in patients with liver disease. Please consult your doctor....
Severely interacts with other drugs like
Tacloran 1mg Capsule, Tenof 300mg Tablet, Tacsant 0.5mg Capsule, Lasix 40mg/4ml Injection
Patient Concerns
Frequently asked questions for Vanmycetin T 0.3% Drop
Frequently asked questions for Tobramycin
Q. Is tobramycin a sulfa drug or penicillin antibiotic?
No. Tobramycin is an aminoglycoside antibiotic used to treat Pseudomonas infections and other serious infections in patients (6 years and older) with cystic fibrosis
Q. Does tobramycin treat styes, Pseudomonas, pink eye, staphylococcus and methicillin resistant staphylococcus aureus (MRSA)?
Tobramycin/dexamethasone combination can be used to cure pink eye and styes, which are superficial eye and eyelid infections. Tobramycin treats Pseudomonas infections however it is not drug of choice in the treatment of staphylococcus or MRSA
Q. Is tobramycin safe for infants?
No. Due to high propensity for kidney and internal ear damage, tobramycin shouldn't be given to infants
Q. Is tobramycin over the counter?
No. Tobramycin belongs to schedule H and can be obtained only on production of valid prescription
Q. Is tobramycin the same as ofloxacin?
No. Tobramycin and Ofloxacin belong to different class of antibiotics, and are used to treat different sets of infections.
Substitutes for Vanmycetin T Drop
Tobrabact 0.3% Drop
Novartis India Ltd
₹5.5/ml of Drop
63% costlier
Tobracad 0.3% Drop
Zydus Cadila
₹7.8/ml of Drop
131% costlier
Tobracin 0.3% Drop
Micro Labs Ltd
₹9.75/ml of Drop
188% costlier


text:
- Please select a date to see the proper prices!
Description of the accommodation:
Rooms, services Either for a pleasant weekend or a longer holiday in France, you may make a good decision by choosing Hotel de la Mer Pléneuf-Val-André. 12 comfortably furnished rooms are offered by the hotel to guests looking for accommodation in Pléneuf-Val-André. In the safe your valuables can be the safely secured. The exact scope of services offered by Hotel de la Mer Pléneuf-Val-André (including those for an extra fee) is available on the information sheet below.
Payment For the reservation you may need to provide advance payment by credit card or credit card guarantee, depending on the exact date, room and price.
Arrival, opening hours The earliest check-in time to your room is 15:00, the latest check-out time from your room is 11:00. The personnel can speak French and English languages.
Hotel de la Mer Pléneuf-Val-André rooms Rooms
- Please select a date to see the proper prices!
Accommodation services
Pet friendly, Safe deposit box
Hairdryer, Desk in the room


text: Hi guys i would just like to say thanks for the wealth of information that is on this site, truly fantastic stuff. Am a bit of a noob really and am really taking all this new info that you guys post on this site, i would say that these forums are one of the most usefull and informitive i have ever came across. Am trying to learn as much as i can absorb and try and make a few £££ if i can, keep up the awesome work guys. THANK YOU RICHIE:23:


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Mary, you are taken up to heaven; call me to be a child of God.
1) Come then my love, my lovely one come. For see winter is past, the rains are over and gone. The season of glad songs has come.
2) Show me your face, let me hear your voice, for your voice is sweet and your face is beautiful. You are wholly beautiful my love, and without blemish.
3) Arise, shine out, for your light has come; the glory of Yahweh is rising on you, the nations come to your light, and kings to your dawning brightness.
4) The Spirit and the Bride say "come". Let everyone who listens answer "come". Then let all who are thirsty come, to have the water of life, and have it free.
5) One thing I ask of Yahweh - one thing I seek. To live in the house of Yahweh all the days of my life.
6) To enjoy the sweetness of Yahweh, to marvel at His goodness, in the land of the living.
7) In my Father's house there are many dwelling places; otherwise how could I have told you that I was going to prepare a place for you?
8) I shall make an eternal covenant of peace with them, I will settle My sanctuary among them for ever. I will be their God, and they will be My people.
9) The Lord will remove the mourning veil covering all peoples, He will destroy death for ever.
10) The Lord Yahweh will wipe away the tears from every cheek. We exult and we rejoice that He has saved us.
All Images copyright © 2002-2017 Reimar Gaertner


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Our Science Lab
On Thursday, February 10, 2011, we held the Grand Opening of our Science Lab at DBP. Parents, teachers, and children got their first look at the beautiful murals, classroom animals, unusual specimens, books, and a variety of manipulatives that are used to provide a hands-on experience for our students.
The one-of-a-kind murals will take you to the waters' edge of a pond. You feel like you are standing among the animals as they swim, walk, or fly by. Some of the murals depict the life cycle of a frog, caterpillar, or bird. Each time you look at them, you discover a new and amazing animal. Ming-Su Wang, a beloved teacher at DBP, painted all of the murals. We thank her from the bottom of our hearts for sharing her wonderful gift with us.
We have a sweet Russian Tortoise named Tillie, a curious Bearded Dragon named Louie (Pasteur), four Fire-bellied Toads, and an aquarium with assorted swimming beauties!
Our lab includes unique specimens such as: an alligator skull, turtle shell, emu and ostrich eggs, a variety of bird nests, wasps' nest, 'found' butterflies and bugs, horseshoe crab exoskeleton, sharks teeth, and more! We are always on the lookout for new donations!
We have many non-fiction books with beautiful photographs to help children see what they can only imagine. Manipulatives are used to show how simple machines work; equipment and supplies are on hand to conduct a wide variety of experiments.
Paula Costello is our inventive Science teacher, Monday through Friday for our Toddlers, 2's, 3's, 4's, and 5's. She provides a diverse assortment of hands-on experiences, games, and experiments. Taking care of and feeding the animals is a favorite activity for all of the classes!
A new addition to the lab is an Epson Interactive Whiteboard. We are excited to have the ability to view world science events and wildlife habitats; along with the addition of fun, interactive software for early childhood classrooms.
The children continue to inspire us to improve the lab through their inquisitive nature, and thirst for learning.


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Security Division
Today's aviation security challenges are intense and far-reaching.
Under Centurion's watch, no cargo goes unchecked; no person goes unseen.
Our Security Division enforces pro-active measures to strengthen its security presence, thus eliminating crime on its premises.
While cargo crime is a reality at Miami International, our Security Division has successfully thwarted most offenses. We are achieving these tremendous results by:
- Partnering with MIA's law enforcement agencies
- Collaborating on investigations with the law enforcement agencies
- Receiving daily advisories from Homeland Security's law enforcement departments
- Doing extensive background and screening checks on all employees, including FBI fingerprinting, SIDA clearance and AOA badging
- Certifying all security officers, who then undergo intense on-the-job training
- In-house state-of-the-art CCTV system, with over 200 cameras, providing continuous surveillance of our facility and its perimeter
- Regular Homeland Security Vulnerability Assessments
- Screening of cargo, crew, passengers and baggage
- Access control in the High Value Cargo area, which includes real-time reporting at the various stages of arrival, palletization and loading
Centurion Cargo's Security Division specializes in loss prevention, safety and risk management.
With security services provided 24/7 – 365 days a year – we ensure that YOUR cargo is securely handled at our facility.


text:
Quick Details
- Place of Origin: Guangdong, China (Mainland)
- Brand Name: Huidu
- Model Number: HD-D30
- Usage: Out door/in door/semi-outdoor
- Tube Chip Color: Full Color
- Display Function: for single-dual and full color
- Pixels: 10mm
- Screen Dimension: 1024W*64H
- Certification: CE,RoHS
- Function: Video,Image and Text Editing,U-disk expanding memory,plug and play.
- Type: Support indoor & outdoor full-color & single/dual color module
- Module IC type: Support MBI5041/5042,MBI5050,MY9221,MY9221,MY9268 etc and PWM
- Scan mode: support 1-32 scan randomly and static
- Control range: 1024w*64h
- Gray Scale: 0-256
- Video format: support AVI,WMV,MP4,3GP,ASF,MPG,FLV,F4V,MKV,MOV,DAT,VOB,TRP,TS,WEBM
- Image format: support BMP,GIF,JPG,JPEG,PNG,PBM,PGM,PPM,XPM,XBM etc.
- Software: HDPlayer
Packaging & Delivery
|Packaging Details
|Carton and bag packing for HD-D30 control rgb LED scrolling message sign LED display system.
|Delivery Time
|Usually 2-3 days based on your Quantity
Product Description
HD-D30 control rgb LED scrolling message sign LED display system.
1).Support indoor & outdoor full-color & single/dual color module.
2).Control range Pixel:1024W*64H
3).Support 256 Gray scale.
4).Support Video,Animation,Image,Neon,Office file etc .
5).Support U-disk expanding memory, plug and play.
6).Plug and play without any network settings.
7).Support Internet /3G/4G Clouds management
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