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This solid oak easel has a mast that adjusts from 30" to 45" (76 cm to 114 cm) high. The adjustable holders have easy-turn knobs and hold a canvas up to 36" (91 cm) in height. The back leg adjusts for a comfortable painting angle.
Assembly is easy! Just slide the mast into the grooves, and slide on the canvas holders. The easel folds down for convenient storage.
Canvas Height
91 cm
Min Height
76 cm
Max Height
114 cm
Folded Height
11 cm
Base Width
46 cm
Base Depth
46 cm
10½ lb
5 kg
Canvas Height
91 cm
Min Height
76 cm
Max Height
114 cm
Folded Height
11 cm
Base Width
46 cm
Base Depth
10½ lb
5 kg
Gift Idea
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(based on 7 reviews)
Ratings Distribution
5 Stars
4 Stars
3 Stars
2 Stars
1 Stars
of respondents would recommend this to a friend.
Reviewed by 7 customers
Displaying reviews 1-7
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Excellent quality
By J from the Cape
from Cape Cod, MA
Comments about American Easel Oak Tabletop Easel:
This easel is very stable, giving me confidence that my canvas won't move while I'm painting even the most intricate objects.
Bottom Line Yes, I would recommend this to a friend
Was this review helpful? Yes / No
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By Thelma
from Abingdon, Virginia
Used this last evening for painting an outdoor wedding, and it's portability was fantastic as well as being very sturdy and easy to set up! I used a table with adjustable legs to work from which also gave me the space needed for my supplies! I am glad I bought this, I believe it will be very serviceable in the future! Thank you for carrying an excellent product!
(1 of 4 customers found this review helpful)
The quality is good enogh for me
By Myung
from New City, NY
For painting
(2 of 2 customers found this review helpful)
By TGROGG
from NEWPORT BEACH, CA
(1 of 2 customers found this review helpful)
This little easle works great.
By Leigh
from The Ozark Mountains
I have been looking for a solid tabletop easel for a long time. This one works great! It is heavy enough to hold against any king of assault I make on my work, and it is compact and easy to move. I had to modify the hardware a bit to suit myself, but that was also easy. Solid construction and materials.
(5 of 5 customers found this review helpful)
3rd easel was a charm, first 2 busted
By Happy when creative
from New York, NY
I ordered this easel with high expectations. The first one was poorly constructed. the bottom ledge was not cut properly to slide onto the mast. I first called the manufacturer. I encountered a very rude woman whom told me to call the company I ordered from and hung up. When I called Blick the customer service was more than accommodating in sending another out. The second one... same problem. the grooves in the bottom shelf?ledge did not line up with the mast grooves. How aggravating! I just wanted to start painting already! I contacted Blick and again the customer service was really great. I was told the the next easel sent out would be inspected by the warehouse. When it arrived I hesitated opening it at first. I was afraid I would be disappointed again. Well the 3rd easel was a charm! The shelf ledge slid easily on the mast, no problem! I'm glad I finally got a good one!The easel might be hit or miss, depends if you have the time and energy to deal with sending it back... ( I don't have a car so this meant lugging it many blocks away to the closest Fedex each time I had to return them)Blick customer service was outstanding!! I fell safe guarded when ordering from them
Merchant response: Blick attempts to send out every order free from defect or damage. However, these types of issues do arise occasionally. We apologize for this. Customers who receive damaged or defective items should contact our Customer Care Center via email or by calling (800) 723-2787 and we will work with you to rectify the situation.
great item
By howica
from delray beach, fl
very solid and sturdy, attractive looking, well made, great for tabletop use
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Please allow ADDITIONAL DELIVERY TIME for factory-shipped items.
Click here to view expected shipping dates, or call our Order Dept (800)-828-4548.
Copyright © 2015 Dick Blick Art Materials. All rights reserved.
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Dick Blick Art Materials · P.O. Box 1267 · Galesburg, IL 61402-1267 · Toll-free Phone (800) 828-4548 International Phone +1-309-343-6181 ext. 5402 · Fax (800) 621-8293
Dick Blick Art Materials®, Blick®, Blick Studio®, and Artists Pick Blick® are registered trademarks ofDick Blick Holdings Inc. © Copyright 1999-2017 Dick Blick Holdings Inc. All rights reserved.


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Discussion in 'Odds & Ends' started by SydneyJim, Jul 21, 2006.
i have no clue why i'm awake and i have practice @ 7am
Try finding the most boring reading material you have around and reading it in the most comfortable position you can get into.
Good luck.
And if you don't like to read, try reading something you ARE interested in so at least you'll make the effort in reading.
You'll be out like a baby in no time.
holy crap i was dead @ practice
I listen to the BBC World Service at night. It usually knocks me right out. And if I happen to stay awake for any amount of time, I might actually learn something.
What i do, is bring my mp3/recorder to the Sunday sermon, and record the pastor....i then heard the recording as i go to bed, kills me within 5 minutes. He has a type of hypnotic voice...its weird.
I tried reading A Brief History of Time, by Stephen Hawking a few nights ago so I would fall asleep. I nearly finished the book before giving up. After I stopped reading, I fell asleep almost immediately.
The trick to stop sleeping late at night is to bore yourself and don't allow yourself to enjoy what you're doing at the time otherwise you'll end up altering your pattern. I learned this in psych 110 hehe.
Brilliant - best post I've read in ages
Separate names with a comma.

subset: commoncrawl


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Proxy Profits :: Your Definitve Guide on How to Make Money Online With Proxies
Proxy Profits :: Your Definitve Guide on How to Make Money Online With Proxies
There are over 31 billion searches in google every month. That is 5 times the entire worlds population finding answers to life's least important questions, every month. In 2006 this number was just 2.6 billion. That is a 1200% increase in just a mere three years. We are living in exponential times and our world is getting smaller at an astonishing rate, internet privacy and security has never been more important than it is right now. The most common way to browse the internet with unparalleled safety and anonymity, not to mention unblocking previously blocked websites, has been to use a proxy server.
A proxy server acts in much the same way as a human proxy does, it is a web-based representative for your computer. When you surf the internet using a proxy, no one sees you or your computer, they only see the proxy that is doing your dirty work. This means that you can sneak past all the virtual bouncers that have locked you out of your favorite websites at work or school, you can visit all the naughty sites you wish without your significant other finding out, and no hacker will discover your ip address and steal all of your data.
So we have so far established that there are more people surfing the web now than ever before, and that these people are in dire need of a little privacy and security. We have also learnt that a web proxy is the best solution for these people. So the only conclusion we can therefore reach is that proxies must be extremely popular. But who runs and profits from these traffic magnets? that's where this article comes in. After reading this you will be ready to set the foundations for your money spinning proxy empire!
I am going to talk about two ways of getting into the proxy market, by owning a proxy network, and by owning a proxy lister.
Proxy Networks
A proxy network is, believe it or not, a network of proxies. The concept is very basic, each proxy server that you own makes money by displaying ads and such, so it only makes sense to multiply your profits by making more proxies. All of the proxies that you own is called your proxy network, each and every one of these proxies make a bit of money, and put together a network of say 10, 100 or even 1000 proxies and you have the potential to rake in some really serious cash.
To build a proxy server you need only 4 things:
Hosting A Domain Name A good Proxy Script A bit of know-how (supplied here)
Hosting and Domains
I am not going to go into hosting and domain names too deeply, as there are literally hundreds of equally good hosting companies and domain registrars to choose from that will serve your purposes perfectly. What I will say is that I recommend you register a domain name with a different company than your hosting provider. More and more hosting providers are getting the nasty reputation of playing hostage with your domain names when you choose to terminate a contract, so it's best just to play it safe and go with a dedicated domain registrar.
Try and avoid using 'proxy' in the actual domain name as many school and work content blockers have 'proxy' on their blacklist. When trying to register a domain, the TLD (.com, .net, .info, etc.) is not too important, you are going to have to register a lot of domains, so going for the cheapest option would make sense. For the domain registrar to go with, I personally use and recommend Namecheap They offer great support and competitive pricing, if you can find a better deal then take it. Remember the only thing that changes in domain registrars is their level of support and pricing, all services do the same thing.
As far as hosting goes, I can only suggest that you either go with a specialized 'proxy hosting' package that many hosting providers are offering now, or go through your chosen hosting companies TOS (terms of service) with a fine toothed comb. A lot of hosting providers don't like hosting proxies on shared accounts because they can be a bit of a resource hog. Other than this, just make sure you have enough disk space and bandwidth to suit your needs.
As a general rule I try and stay away from hosts that offer 'unlimited' disk space and bandwidth. There is obviously no such thing as unlimited resources, and the providers that offer this usually place unfair restrictions on other aspects of their service, so that you could never possibly use your 'unlimited' bandwidth and disk space. The same goes with hosts offering ridiculously large amounts of disk space and bandwidth, something like 10TB for /month is obviously not realistic and buried in their TOS you would likely find page after page of restrictions that could cripple your account and get you banned.
Proxy Scripts
Now for the most vital part of your proxy network, the proxy script you choose to use. There are two routes you can take here, using free scripts, or a proper product. If you are a do-it-yourself kind of person and know your way around programming in PHP, and you don't mind spending more time working without support to save money, then the free route would be for you. I am not that kind of person, and would rather pay a little bit extra to get into the fast lane for success, for peace of mind, a quality product, and a helping hand when I get frustrated trying to fix a proxy at 3 o'clock in the morning. If you choose to go down the paid route, you can't really look past the products offered by ProxyNiche
ProxyNiche is pretty much the leader in the proxy script market. They have by far the best support in the field, usually getting back to you within 6 hours in my experience, their products are the cheapest as well as the most feature rich in the proxy script market, they are also the most established and reputable company amongst a sea of cheap scams that are there one day and gone by the next. I strongly recommend you use these guys. The script they offer for building proxy networks is called ProxyMan .
ProxyMan is really cool because you can upload and install the script on one domain and have a functioning proxy up in a minute or so, and then create up to 10 000 custom proxies on the fly without uploading any more files or installing any extra copies of the script. This is such a huge timesaver that this feature alone is easily worth the price tag. Once you get the hang of it you can make about 100 proxies in just over an hour and a half. A proxy network of that size would take weeks or even months to build using free scripts or even other paid products.
To build a proxy server with ProxyMan, you just fill out a form located in your control panel. It is all pretty self expanitory, the only thing I suggest is that you put a focus on SEO when writing your content. Think of words that people would search for and try and include these words in your site content, then add these words to your meta keywords list. Remember that you should only include words that you have actually used on the site in the meta keywords field. All you have to do then is park domains to your main site, and fill out another form for each domain.
All the templates included are fairly simple to edit, and if you want small modifications done to them, the support staff could probably help.
Proxy Listers
A proxy lister is simply a website that lists proxy servers for users to find. All proxy servers out there want one thing and one thing only, traffic. By getting listed in a proxy lister proxy servers greatly increase their chances of getting more traffic. Many proxy server owners are desperate enough for traffic that they pay to be listed on proxy listers in order to gain more recognition. By running your own proxy lister you not only have an income from selling advertising space, like with a proxy network, but also from having paid subscribers to your listings.
To build your own proxy lister you need the same 4 basic elements that you do for building a proxy network,
Hosting A Domain Name A good Proxy Script A bit of know how
Hosting and Domains
Basically the same goes for proxy lister hosting as it does for proxy server hosting. The only difference being that you don't need to find specialized proxy hosting. As you are just listing proxies on your proxy lister, there is no heavy load on a shared hosting server, unlike if you were running a proxy network. Again, try and avoid using the words 'proxy', 'unblock', etc. in your actual domain as these are likely to be blocked by content blockers in schools and workplaces, cutting off a large portion of your market. The warning of 'unlimited' hosts also still applies when finding hosting for a proxy lister.
Proxy Scripts
Again, the most vital part of owning a proxy lister is getting hold of a good proxy script, and again ProxyNiche comes to the rescue with their fantastic, and cheap, script, ProxyShout.
Unlike with proxy server scripts, there aren't really too many decent quality free DIY options when building a proxy lister. ProxyShout is on the cheaper end of the spectrum, weighing in at , but it still has all the features you would need to build your own proxy list, and best of all absolutely no knowledge of html or php or anything like that is required at all.
I have only one small complaint with the script. By default, there is a large logo in the top left hand corner of the template that says "ProxyShout". Now, when your trying to build your own custom and unique proxy list, a big bit of 3rd party branding isn't exactly what you want. But not to worry, it is an easy fix. If you hunt around in the in the downloaded package you get when you order the script, you will find a folder called 'img' inside the upload folder. In that folder you will find an image called 'logo.jpg'. If you replace this image with your own logo or title the changes will be made site-wide automatically.
I again suggest that you put a bit of a focus on SEO when you write your content for your proxy lister. With so many people having the same bright idea of diving into this huge market, you can easily get lost to a sea of other listers. But by implementing some useful SEO techniques, you can set yourself apart from the crowd and make some serious cash. The scope of this article isn't broad enough to include information on SEO methods, but with a quick google search you will find all you need to know.
Well, That's all from me for the time being, I hope this article has shed some light on the shrouded world of proxy profits and wish you all the best on your journey to success in the proxy market.
live.pirillo.com – What is a proxy and why would you use it? What types of proxies are out there?
Video Rating: 4 / 5
More Proxies Articles


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MOVIE SYNOPSIS [ General Audiences ] Being a production of Canada, this feature film of 2014 has been excellently directed by Richard Needham. You can watch Asian Action online on TV cable or theaters with original audio in English at different dates. This film premiered in theaters in 2014.
Rating: 5 by 10 users./
Runtime: 4 minutes
Jacky Lai, Warren Chow, Michael Chan and Isabelle Yang.
Short film, Action.
4-minute film (full movie) directed by Richard Needham.
The original audio of Asian Action has dialogues in Dolby Digital, it was produced in Canada.
It premiered in cinemas or television in 2014.
Screenplay written by Richard Needham.
William Reeve.
Richard Needham and Symone Roper.
This film was produced and / or financed by 6618359 Canada.
Composed by Thierry Latremoille.
Iwerks Entertainment.
Without commercial breaks, the full movie Asian Action has a duration of 4 minutes; the official trailer can be watched in streaming on the Internet. You can watch this full movie free in EnglishDolby Digital in movie TV channels, renting the DVD or with VoD services (Video On Demand player, Hulu) and PPV (Pay Per View, Netflix).
See the page of this full movie, Asian Action in FULLTV Movies.


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With First Tutors: Music you can locate a Bridgwater violin teacher. Violin lessons are a brilliant method to begin a stimulating new hobby, pick up a new skill and gain confidence in violin. Use our site to search for Bridgwater violin teachers and determine which matches your requirements so you can start your violin tuition in Bridgwater immediately!
First Tutors: Music is the best way to contact Bridgwater violin tutors in the UK, helping you discover Bridgwater violin lessons close to home and Bridgwater tutors to assist with any instrument like piano, violin or guitar. We can help you find Bridgwater violin tuition or a one-to-one Bridgwater violin tutor to prepare for violin exams and develop your violin skills! We order Bridgwater violin teachers local to you according to their hourly charges and distance from you.
If you are a violin teacher and would like to offer violin tuition services in Bridgwater or anywhere else across the UK, please register with First Tutors: Music or learn about us here. Becoming a Bridgwater violin teacher is a great way to re-affirm your own skills through providing violin lessons while assisting others, all in the Bridgwater area!


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Know more about this business than we do? Cool! Please submit any corrections or missing details you may have.Help us make it right
Be the first YellowBot user to add photos or videos of C & M Auto
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C & M Auto is located at 112 E Atlantic St, Branson, MO. This business specializes in Ornamental Glass, Metal, & Stone and has 1 review(s) with a star rating of 1.0.
Chocolat is located at 204 N Commercial St, Branson, MO. This business specializes in Food & Agriculture.
If you don't see your business listed on YellowBot, please add your business listing.
YellowBot wants to get your input! If you have a comment, find a bug or think of something neat we should do, let us know by emailing us.
© 2007-2017 Solfo, Inc. – All rights reserved


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Quick Details
- Material: Metal, Aluminum and ABS
- Metal Type: Aluminum
- Shape: Round
- Place of Origin: Zhejiang, China (Mainland)
- Brand Name: OEM
- Model Number: CD301
- Metal coin dispenser: metal coin purse
- Color: silver/black/red/blue/gold
- Size: 83x27MM
- Packing: 1/opp/white box
- Printing logo: laser printing/silk-screen
Packaging & Delivery
|Packaging Details
|Packing:1/polybag/white box
|Delivery Time
|15-25days after confirming order
Specifications1.Metal coin dispenser in good quanlity
2.Usage:Coin holder
3.Supply Ability 5000pcs/day
Metal coin dispenser (coin dispenser) in good quanlity
1)Item No.CD301
2)Materials: Aluminum and ABS
6)Printing logo:Silk-screen or laser pringting
7)Packing:1/polybag/white box
8)Production time:5000pcs/day
9)Fob port:NINGBO or SHANGHAI
Detail information
Application Description
The color you can choose
Transaction History of the Supplier
Below is the information about the supplier's transactions conducted via Alibaba.com. If you require further details regarding the transaction data, please contact the supplier directly.
Transaction Overview
Export Markets
Transaction Details
This supplier has completedtransactions with buyers from .
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here is an example- 0.05 would that convert to 5/100 or 50/100 or 5/10?
A method that always works is the following. Let x equal your decimal, in this case x = 0.05. Now what do you have to do to this equation to eliminate the decimal? In our case, multiply both sides by 100, so
100*x = 5
Thus, x is 5/100, or 1/20, whichever form suits your purpose.
Sometimes, the method is a little tricky. For example, suppose the decimal is the infinite string 0.33333... In this case, my equation is x = 0.333333... If I multiply both sides by 3, the equation becomes
3*x = 0.9999999...
Now the trick is you need to know that 0.999999.... is just another way of writing 1. So the equation is really 3*x = 1, and x = 1/3.


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H.O.C.K. Mattress Cushion Ballet 50x10cm
Mattress Cushion Ballet by H.O.C.K. - cushion with a romantic macramé design on the cover
Description of H.O.C.K. Mattress Cushion Ballet 50x10cm
Charming and trendy! With their round macramé details, the products from the Ballet Series belong to a very unusual, oriental inspired collection. The wonderfully handcrafted macramé details are true highlights.
The pillows are exotic eye-catchers in any interior setting! They are just the right size for relaxing on the sofa or in a Moroccan lounge. Use them as back cushions or simply as decorative pieces! The Mattress Cushions are a cozy alternative for sitting comfortably on low benches, chairs or the floor.
- cushion includes bag insert with solid polyester sticks filling
- cover with zipper
- easy-care; machine washable at 30 °C
- hard-wearing quality
Chic and ultra fancy – that's the Ballet Series!
Art-No.: 583-9505M/VPMeasures: Length 50 cm, Width 50 cm, Height 10 cm
Weight: 0.5 kg
Category: Chair Cushions
Brand: H.O.C.K.
Color: brown; green
Material: 54% polyester/46% cotton
Product Certification:
Product Information:
H.O.C.K. Mattress Cushion Ballet 50x10cm: Reviews
Be the first to write a review for this product!


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Student Career Path Aptitude
I suggest that every person who wants to go into a given health care career (EMT, nursing home care, nursing home administration, nursing of any kind, emergency room care, doctor, alzheimer's/dementia care unit, etc) find out before they get too deep into college/training if they have the empathy and caring to handle the rigors of the job they are getting into. How to do this? "Volunteer" and get student credit for ...more »
Voting on Ideas
Vote for your favorite ideas by clicking on the up arrow.To undo an upvote, simply click the arrow again. This second click removes your vote.


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I'm looking for good place to have a birthday dinner, close to House of Blues downtown. We like fun, fresh, good food.. small plates and romantic a plus, we are light eaters.. Also looking for a place close by for a good cocktail.. fun martini?? Thanks!
House of Blues
329 N. Dearborn, Chicago, IL 60654


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The Sorrows of Dolores Trailer (1986)
Film recounts the madcap tale of sweet Dolores who, after being tortured by her sadistic mother, is thrown into the harsh city environs, innocent and alone. Chased by villains, abducted into white slavery, and ravaged by monstrous beasts, Dolores spirals deep into the underworld unable to find redemption.
Watch the official The Sorrows of Dolores 1986 trailer in HD below or find more The Sorrows of Dolores videos on Vidimovie.


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Tagged With: Open Access
No Responsive Records – Still not listening
These items were requested by Forest Access For All, and denied by the Forest Supervisor Tom Montoya and Regional Forester Jim Pena. We will discuss what this means below the listed items. Response Letter from Regional Forester – 12_27_17_No_Response_FOIA_Response Information requested on – 1) Blue Mountains Forest Plan a) We would like a list of the … Continue reading
Forest Service Delays Release of Final Environmental Impact Statement
You may have recently received a letter or an email from FAFA stating that the Final Environmental Impact Statement (FEIS) would be coming out in September or October. As we read the tea leaves of dealing with the Wallowa-Whitman National Forest Supervisors office, we fully expect to see the document in that time frame, and … Continue reading
Forum on the Blue Mountains Forest Plan Revision – Important that folks attend
We apologize for the short notice, but were just informed by one of our members of the following forum. To all our friends in Eastern Oregon – especially in and around Pendleton. Tomorrow evening, April 6th Oregon Public Broadcasting will be taping a "forum" on the Blue Mountains Forest Plan Revision. The invited forum participates are … Continue reading


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Welcome To Cornerstone Family Chiropractic!
Dr. Robison truly feels that children who receive chiropractic care experience a healthier life and have an improved opportunity for learning. Dr. Robison also has a passion for working with children who have developmental disabilities and neurological processing disorders. Dr. Robison is certified in Webster Technique for pregnancy care.
Cornerstone Family Chiropractic
Dr. Dierdra Robison DC
2144 Declaration Drive
Independence, KY 41051
Office Hours
Monday: 8 am – 12:30 pm & 2 pm – 5pm
Tuesday: 2pm – 7pm
Wednesday: 8 am – 12:30 pm & 2 pm – 5pm
Thursday: 2 pm – 7 pm
Friday: 8 am – 12:30 pm
Saturday: Closed
Sunday: Closed
New Patient Forms
Use the following link to print and fill out our paperwork before coming into the office to decrease any possible wait times.


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Traffic : Why we drive the way we do (and what it says about us) Paperback
by Tom Vanderbilt
Get stuck in ... Why do some people become demons when they get behind a wheel?
Why does the other lane always move faster? Why do New Yorkers jaywalk (and nobody does in Cophenhagen)? And why should you never drive with any beer-drinking, divorced doctors named Fred?Driving is about far more than getting from A to B.
As Tom Vanderbilt's brilliant, curiosity-filled book shows, it's actually the key to deciphering human nature and ... well, pretty much everything. From the etiquette of horn-honking to bumper stickers you should avoid, from gridlock in ancient Rome to why getting rid of road signs actually reduces accidents, Traffic will change the way you see yourself, and other people (and not just through your windscreen).
- Format: Paperback
- Pages: 416 pages
- Publisher: Penguin Books Ltd
- Publication Date: 01/08/2009
- Category: Roadcraft, driving & the Highway Code
Other Formats
- EPUB from £6.99
- Hardback from £10.09
- eAudiobook MP3 from £10.38
Free Home Delivery
on all orders
Pick up orders
from local bookshops
Showing 1 - 2 of 2 reviews.
Review by sirfurboy
A well researched and thorough book that reads like a good article in "Wired" but book length! A little US centric but manages worldwide coverage. Topics covered include driving psychology, driving aids, traffic planning, problems with perception and concentration and lots and lots of good statistics. Despite being US centric, the author manages to provide a book that is interesting, and challenging. It is perhaps not a must read for everyone, but if you are remotely interested in why we drive the way we do, and in understanding our fellow motorists, this is a book for you. If you want to be a better driver, there is also plenty of good information here - but it is not primarily an advanced driving manual. Nevertheless it repays the time spent reading it.
Review by jintster
This follows the template of Freakonomics blending economics. sociology and phychology with counter-intuitive results. Unfortunately, it very much has the feel of a book comissioned to jump on the Freakanomics bandwagon. Here's an interesting subject - I'll write about 10 issues, roughly 25 pages each - please can I have an advance? The results are patchy. Some of the chapters are very interesting - notably those on cultural differences in driving, the economics of congestion and the Dutch experiments on integrating vehicles and pedestrians. Others feel like filler, with a whole chapters devoted to subjects that could have been dealt with in a shortish magazine feature. As a consequence, more than half the book is repetitive and some times tedious. Vanderbilt is preofessional and objective throughout but its hard to detect any passion for the subject. The prose is very competent in a journalistic style but rarely inspiring. It's a shame because, this is a good subject and if the book were cut down a bit and other aspects of traffic dealt with (some more history would have been appropriate, for example) it would have been much more successful.
Also by Tom Vanderbilt | View all


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Osborne, not Cameron, is now running the show
The prime minister seems focused on Europe
The budget shows how clearly David Cameron has checked out of domestic politics and how George Osborne is now almost entirely in charge. When the Conservatives took office alone this May, Osborne was elevated to second-in-command. He now stands in at prime minister's questions when the boss is abroad. But it also seems that he stands in while the prime minister's mind is abroad — and with the EU referendum on the horizon that appears to be most of the time.
Two of the smaller policies announced by the chancellor on Wednesday demonstrate to those in the know a dramatic shift in dynamics between the two men I saw working together for five years when I was Nick Clegg's policy director.
Osborne raised the issue…


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Gulfport's Get Rescued
Gulfport's Get Rescued and Tails at Twilight
will take place on:
Saturday, February 25, 2017
10:00 am to 6:00 pm
Historic Gulfport Waterfront District
3129 Beach Boulevard South
Gulfport, Florida 33707
Gulfport's Get Rescued – 13th Anniversary
Gulfport's Get Rescued, the animal rescue festival and fundraiser, is preparing for its 13th annual event to take place on Saturday, February 25th, 2017.
This popular event has evolved from one block and a handful of animal rescue groups in its first year to a popular and festive event representing rescue groups from throughout the region. Gulfport's Get Rescued is one of the largest animal rescue events in the state, with all profits to benefit participating non-profit rescue groups.
From 10am to 6pm, animal rescue organizations, many appearing with adoptable pets, take over Beach Blvd. to raise money and awareness for their causes.
Additionally, animal-related vendors, artists and crafters offer their wares to festival-goers. Pet Related activities will include an adoptable pet parade, pet care education, pet services, a pet food and supplies drive, animal rescue groups, free samples, training demos, a Bark-B-Que, food, DJ music & more. Each year, thousands of attendees, many accompanied by their own critter companions, make their way to Gulfport to participate in what has become a beloved tradition.
Well behaved pets and their leashed people are welcome!
The daytime event is free for the public to attend, with plenty of free parking in and around the area.
Gulfport's Tails at Twilight
Saturday, February 25th
7:00 p.m. to 10:00 p.m.
Gulfport Casino Ballroom
5500 Shore Blvd. South
Gulfport, Florida
A special event will offer animal lovers an evening of fun to support non-profit animal rescue groups.
Tails at Twilight will take place on Saturday, February 13th from 7 p.m. to 10 p.m. at the historic Gulfport Casino, 5500 Shore Boulevard South.
Tails at Twilight is the popular evening component of a full day of festivities that begin with Gulfport's Get Rescued, the free annual pet adoption street festival and fundraiser held on Beach Boulevard on the same day from 10 a.m. until 6 p.m.
But after the pets have gone to bed, all are invited to a lively evening of festivities for humans that will also raise funds for the important cause of animal rescues.
A complimentary tapas buffet, cash bar and festive décor will add to the party atmosphere.
All net proceeds from ticket sales and auctions will be donated to the non-profit rescue groups.
Participating rescue groups last year included Boxer Rescue Angels of Florida, Dalmatian Rescue of Tampa Bay, English Springer Rescue, Florida Boxer Rescue, Heidi's Legacy Dog Rescue, Limbo Chihuahuas, Pawlicious Poochie Pet Rescue, Pit Bull Happenings, Save our Strays and Second Chance for Strays.
Additional participating groups may still be announced.
Tickets for Tails at Twilight are $25 each.
Advance tickets may be purchased at the Gulfport Welcome Center (3101 Beach Blvd., Suite 1), Gulfport Beach Bazaar (3115 Beach Blvd.).
You can also purchase tickets with a credit/debit card or Paypal buy following the Buy Now link below.
Please print out your online purchase confirmation as proof of payment so that you can redeem your tickets at the door.
Gulfport's Get Rescued and Tails at Twilight are sponsored by the non-profit Gulfport Merchants Association.
For more information on Tails at Twilight, or to purchase advance tickets, please contact:
Lacey Glass by phone at (813) 495-9039 or email email@example.com .
To find out more about Gulfport, go to VisitGulfportFlorida.com.
Enthusiasts can become involved in Gulfport's Get Rescued by sponsoring an individual animal rescue group for $75, which will include a prominent sign at that group's Beach Blvd. booth during the event.
Local businesses are also encouraged to donate items for live and silent auctions, with the proceeds being divided among the participating rescues.
Visitors and attendees are encouraged to bring donations of dog and cat food, cat litter and pet supplies. Drop-off locations will be conveniently located on Beach Blvd at the intersections of 128th Ave S and Shore Blvd or at the Welcome Center at 3101 Beach Blvd. S.
Donations prior to event day can also be dropped off at 5225 15th Ave S., Gulfport. Contributions will be distributed to participating rescues on the day of the event.
Gulfport's Get Rescued is proudly hosted by the not-for-profit Gulfport Merchants Association, with 100% of the events net proceeds being donated to animal rescue.
The event is co-sponsored by the City of Gulfport, Pet Supermarket, Pet Passages by Anderson McQueen, The Gabber, BeachLife, Paradise News, Olympus Printing, Rainbow411.com, GSH Radio.com, Salty's Gulfport, O'Maddy's Bar & Grill, Stella's Deli, Smokin' J's BBQ, Beach Bazaar, The Tampa Bay Adventurers and many more local community sponsors.
To become a supporter, please call SIK Promotions, Inc., at (727) 322.5217.
For more information on Gulfport's Get Rescued, visit www.facebook.com/GetRescued
Pet friendly vendors and rescue groups can download the applications at www.SIKPromotions.com under the vendor info tab.
3101 Beach Boulevard South Gulfport, FL 33707


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Death and Taxis Trailer (2007)
18 May 2007
Take a fascinating journey in Death And Taxis where the journey is the destination, and the next world might be just a cab ride away. Hugging the double-yellow line between this life and the next, one big city taxi carries the stories of several drivers and passengers, each contending with intensely psychological and sometimes supernatural brushes with death. Whether profound, funny or simply creepy, these vignettes come to life and afterlife in the hands of a diverse group of acclaimed actors.
Watch the official Death and Taxis 2007 trailer in HD below or find more Death and Taxis videos on Vidimovie.


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Textile firm fined for pollution and IPPC failures
Textile processor Colours Dyers and Finishers has been fined for breaching its pollution prevention and control (PPC) permit and polluting the river Soar.
Sorry you do not have access to this article. Please contact Customer Support at
or call 020 8267 8120


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|16 Jan 2014
Microsoft Windows 7 Professional 64-bit 7601 Multiprocessor Free Service Pack 1
Multiple games crashing at startup
Hi there,
My problems began when I tried to run Endless Space (steam). It crashes as soon as I launch it. The screen will go black, and then seconds later it will crash to the desktop with the message "A problem caused the program to stop working correctly. Windows will close the program and notify you if a solution is available."
After posting on the developer's forum and trying some fixes I found there, I encountered the same problem with the game Smite by Hi-Rez, leading me to believe that this is not an Endless Space error but something else. My graphics drivers are up to date.
I have tried:
Uninstalling and re-installing games
Turning off firewall and anti-virus
Running Smite in compatibility mode
Changing the launch settings in Endless space to "-novideo" (interestingly this actually got me to a loading screen before the game crashed)
Uninstalling and then reinstalling various versions of the VC Redist file accompanied by a restart (including the file that came with Endless Space)
Other games (Civ V, WoW, Starcraft III) work fine.
Attached are the event viewer details. Thanks for your help!
|My System Specs
|19 Jan 2014
Update or rollback your graphics drivers. Also check game's cache integrity with Steam (search on google how to do it).
|My System Specs
|24 Jan 2014
Windows 7 ultimate x64
Two events mentioned in your post links to Nvidia Drivers. Uninstall the drivers that you have and run "Driver Sweeper" to clean the leftovers of the driver. Install the latest drivers now.
|My System Specs
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Saturday, September 2, 2017
Saturday, July 8, 2017
Tuesday, July 4, 2017
Wednesday, June 28, 2017
Are all sugars/sweeteners equal?
If you check your labels for the sweeteners in your products, don't forget to consider it's Glycemic Index along with the caloric content. Don't be fooled by marketing descriptions such as "natural", "low calorie", or "no sugar added".
In 1980, The Glycemic Index was conceived by Dr. David J. Jenkins and his associates at the University of Toronto. It's merely a number that indicates the food's effect on your blood glucose level, 100 being the standard which represents pure glucose.
When choosing what sweetener to use, or if you are analyzing what product makes more sense for your diet, don't forget to consider it's Glycemic Index along with it's calories.
Saturday, June 17, 2017
Unexpected threat from low vaccination rates…no treatment available
The return of a rare disease could be devastating. While a cure exists, it may not be not available.
Vaccines have been important elements of public health care, yet over the last decade we have witnessed vaccination rates decrease in various areas worldwide. In general, the reversing trend is in the industrialized world, leading to cases like the measles outbreaks in California in 2015 and Minnesota in 2017.
But there is an insidious downside hiding in lower vaccination rates — what if vaccination rates decrease and a pathogen, once thought eliminated, returns? In some cases the antitoxins used to combat the pathogen are no longer available, or if they exist, they are in restricted supply.
Basically, it is supply and demand. There's no need for anti-sera production when disease incidence is repressed through routine immunization. Who creates an expensive solution to a non-problem? Simply put, no demand, no supply. Existing batches are produced in small labs in a few countries. Laws that have been instilled since diseases were well controlled, often prohibit the movement of blood-derived treatments across international lines. Sadly, sometimes a cure exists, but cannot be implemented.
This situation is highlighted in a case described in the January 13, 2017 issue of Science magazine. A three-year-old girl was admitted to a hospital in Antwerp, Belgium in March of 2016. She was diagnosed with having severe tonsillitis, but physicians noted an unusual thick layer of grey dead cells covering her throat. It was a hallmark symptom for diphtheria known as a "pseudomembrane". Diphtheria is caused by the bacterium Corynebacterium diphtheriae. The initial symptoms present as a sore throat and fever, and can progress to blocking the lungs if left untreated. The exotoxin secreted by the bacteria can also cause damage to the heart and liver.
The disease is treated with antibiotics, and also an antitoxin produced in horses.
However there was no antitoxin available in Belgium to treat this patient. The European Centre for Disease Prevention and Control in Stockholm Sweden eventually was able to locate the treatment in The Netherlands. But it was too little too late, and the infected child died before the life-saving treatment could be administered.
There is a scattering of cases just like this each year. The antitoxin has a shelf life and is produced only in a few countries including Russia, Brazil, and India. A company called BulBio located in Bulgaria is the only producer within the European Union. Strict EU rules regarding importing blood-derived products means the whole EU has only one potential supplier.
In the USA all stores of the antitoxin expired in the 1990's. When cases are reported, the antitoxin must be imported from Brazil.
To make matters worse, there is no incentive to make the antitoxin. It's an expensive process to produce it from horses and doses are inconsistent from batch to batch, meaning a lot of pretesting and quality control are necessary before it may be distributed. To produce them in cell culture would require a new infrastructure and certifications, testing would have to be performed for safety, all which are extremely expensive which makes it a cost-prohibitive, bureaucratic nightmare for any company to undertake to develop a cure for a problem that happens a few times a year around the globe.
In the United States between 2004 and 2015, 2 cases of diphtheria were reported. But in places like Ukraine diphtheria vaccination rates hover below 50%. They are not alone. When a substantial outbreak occurs, where will the treatment come from? It is not a question of "if" — it is a question of "When?"
The diphtheria antitoxin issue raises an important and rarely discussed facet of the vaccination issue. When diseases have been strongly suppressed by routine vaccination, their remedies (all expensive to produce and with a shelf life) fall in short supply. The associated industries have been mothballed and new production techniques are not economically feasible.
The case of diphtheria underscores another reason why vaccination is important. When a defeated disease re-emerges, the cure you or your family critically needs may not be available.
Saturday, February 25, 2017
The Ovarian Cancer-Talc Lawsuit Genesis
Class-action lawsuits were making America Great Again long before it was a thing. Attorneys actively solicit anyone involved (or maybe might be potentially involved) in a particular event, and get them all in one place to file a chunky lawsuit.
This gives a little fuel to the lawsuit for obvious reasons, and is appealing to the "victim(s)" because they do not have to shop out an attorney, and they get to commune with others that were also "victimized". All they have to do is sit back and collect the check.
While it seems like a possible lottery ticket based on the marketing from the commercials, this is rarely a windfall for the consumers, and mostly the attorneys profit while the defendants get a check in the mail that would barely buy a dozen doughnuts.
Recently a wide net has been cast for class action lawsuits trying to fish out women who sprinkled baby powder down their bloomers. The connection between cosmetic talc and ovarian cancer is not obvious, and a good subject for A Look Deeper.
How could baby powder induce a problem in the ovary? That's one anatomical gem tucked pretty far out of harm's way. Someone must have been doing something really wrong!
To explore the basis of this non-intuitive association I explored the peer-reviewed literature and found an especially informative review on the subject (Muscat and Huncharek, 2008). Here I'll review their review for the purpose of providing some backstory to the curious television legal solicitation.
The story begins with talc, a silicate compound, and a cousin of asbestos. Asbestos has been known to be a lung carcinogen, and in 1978 a survey of talc-containing powders found cancer-causing silicates in about 50% of commercial talc powders. While these were thought to be potentially problematic for lung cancers, there was no concern about other uses. Cosmetic talcs cleaned up after that.
The connection to ovaries starts with perineal dusting. Sounds like the name of a righteous rock band, or perhaps what I pay the cleaning lady to do, but it is the practice of applying talc to the perineum. In case you forgot, you should know the perineum from childhood as the low spot on our baby doll's torso where they'd put a hole for drainage or air expansion. The undercarriage. Apparently a dusting of talc was present on many feminine products or added as a cooling powder to undergarments during daily wear. So at least the silicate compound was getting into the right neighborhood.
Still no concern to anybody until 1982. A case-control (retrospective, survey-based) study on ovarian cancer patients revealed a slightly higher than normal association between the disease and perineal dusting. Complicating matters, it is never clear which products used this way actually contain talc. On top of that, the authors propose that the personal nature of perineal dusting could also affect the responses of those responding. Not everyone wants to admit to powdering their parts. Once again you can always find correlation with no causation, and many times that is enough to cause mass hysteria.
The rather loose association was sufficient to ignite the news media at the time, and for decades to follow this connection stewed in the back ground of cancer causes. Then in 2006 the International Agency for Research on Cancer promoted perineal talc use as a "probable carcinogen", using its extremely conservative interpretations of available evidence.
There is no compelling direct mechanism proposed. Unlike asbestos, talc is not fibrous, and it is known to not be genotoxic. Hypotheses revolving around inflammation and even induction of specific antibodies have been proposed, but consistent supportive evidence is lacking, and indirect evidence is not pointing to these mechanisms.
The other question regards how the external genital dusting migrates up the genital tract, through the vagina and cervix, across the uterus and fallopian tubes, to the ovaries. Such journeys defy gravity and the known flow of mucous which favors an external direction. Still, there is no question that talc particles have been detected in some cancerous ovaries. Others detected no evidence of ovarian talc in known perineal dusters, and found talc in ovaries of non-dusters. It was also considered possible that the particles could go to the ovaries via inhalation. Talc on condoms and diaphragms was also considered, but no associations were observed.
This last observation is of particular importance. There is no evidence to support the hypothesis that talc leads to cancer in relation to birth control devices that were treated with talc for years. No relationship was seen between cervical or uterine cancer. These findings indicate no associations when the alleged induction agent is placed directly into the genital canal.
Occupational exposure in talc factories showed no higher incidence of lung or female reproductive cancers, and animal studies also showed similar outcomes.
The authors conclude that the data do not support the causal association between talc-based powders and ovarian cancer. They conclude that the data are not sufficient to draw the conclusion. On the other side, there may be genetic components and predispositions that could lead to carcinogenic potential in specific patients.
Based on this review of the literature the commercial for the class-action lawsuit seems to be based on rather tenuous evidence. The lack of dose-response data, the fact that there are no associations with cervical or uterine cancers, and the fact that talc-dosed birth control had so association either. This appears to be another case where lawyers were effective in swaying a jury with less-than-conclusive science.
Muscat JE,Huncharek MS. Perineal Talc Use and Ovarian Cancer: A Critical Review. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP). 2008;17(2):139-146. doi:10.1097/CEJ.0b013e32811080ef.
Monday, February 6, 2017
Resurgence in 'mad cow disease'? Recent death sparks focus on mystery prion protein
Resurgence in 'mad cow disease'? Recent death sparks focus on mystery prion protein: The original wave of mad cow only infected a limited number of people with a very specific genetic signature. Can we prevent these mystery brain infections from reoccurring? The answer may be in our prions.
Tuesday, January 31, 2017
Gene editing breakthrough in Leukemia treatment
The story of the two English infants treated for leukemia circulated quickly on the internet. But the stories left a few questions unanswered. What exactly were these revolutionary genetic therapies?
Gene editing is a promising new genetic engineering technique poised to have great impacts in medicine. The first edges of the technology are now in clinical application, and results published in Science Translational Medicine.
Researchers in the UK have used these techniques to make sure that new anti-cancer therapies using genetically engineered donor T-cells, can attack cancer while not being rejected or suppressed by chemotherapy. The genetically modified therapy was delivered to two patients- both infants.
The work was published Science Translational Medicine (Qasim et al., Jan 25 2017).
TALEN is a method of disrupting the function of a specific gene. A nuclease (an enzyme that cuts DNA) is encoded by a virus that enters the cell. The nuclease also comes with instructions on the gene to cut, and in the case of the T-cells two genes were disrupted to make the immunotherapy treatment more effective.
The real excitement of this work is not that genetically engineered cells worked well against leukemia. That's been demonstrated pretty well already. This work shows that donated cells can be made into universal, off-the-shelf therapies, not requiring a personalized, autologous match. It potentially widens the applicability and immediacy of the therapy and would probably lower the cost significantly.
The story received some play in popular press, but I could not locate information on the exact genetic changes outside of the original paper, which is what I'm describing herein.
The approach was based on cells that were engineered with a relatively new technology called gene editing. In contrast to what we normally think of as genetic engineering, where a gene is added or information provided to turn a gene off, here the function of specific target genes was abolished using a technique called transcription activator-like effector nuclease (TALEN) editing.
The story begins with the genetically-modified T-cells. T-cells (T-lymphocytes) are white blood cells named for the thymus gland, the place where immature T-cells (stem T-cells) differentiate into mature T-cells (as opposed to B-cells, another type of white blood cell--which arise from bone marrow). T-cells patrol the body, looking for non-self foreign cells, identified by their antigens- proteins that cover the outside of the cells. They generally refrain from attacking "self" cells, which is a problem in cancer. Cancer cells are "self" cells.
But in the case of leukemia, malignant white blood cells express a unique surface antigen called CD19. For several years now, T-cells have been engineered to target CD19+ cells and the therapies have been quite effective. However, they typically involve self-donating the T-cells and having them re-administered once modified to attack the B-cells.
Juno Therapeutics and Novartis have developed auto-donation treatments by using patient's own blood cells, engineering them, and then re-infusing them. In their studies, about half of patients are permanently in remission after receiving altered versions of their own blood cells. The setback for this treatment is the expense, the time involved in harvesting the blood cells form the patient, and the effort to transport the new cells back to the patient. There is great interest in creating a universal T-cell type programmed to target CD19.
Another problem is that when the cells are administered, the body can react harshly with a process recognized as "cytokine release syndrome", recognized from a systemic inflammatory response and high fever. It is like being hit with an amazingly strong flu, and can be fatal, especially in some fragile patients.
The Fragile Patients
The infants, 11 and 16 months old, had undergone traditional chemotherapy for leukemia that was not successful. In this case they were treated with traditional chemotherapies as well as the modified T-cells. Thus far the therapy was successful, both of the infants are now in remission. It cannot be definitively determined if the success is due to the chemotherapy or the T-cell treatment, although it is most likely the latter, as both infants had relapsed from previous chemo treatments.
What is Leukemia?
Leukemia is a group of cancers arising in bone marrow and result in high numbers of underdeveloped white blood cells called blastocytes. White blood cells (leukocytes) are the part of our blood that has an immune function. There are four main types of leukemia, but there are other rare forms, these infants suffered from acute lymphoblastic leukemia (ALL). The average five-year survival rate in patients with Leukemia is 57% in the United States. The five-year survival rate for children under fifteen is ~ 60 to 85%.
Leukemia is a group of cancers arising in bone marrow and result in high numbers of underdeveloped white blood cells called blastocytes. White blood cells (leukocytes) are the part of our blood that has an immune function. There are four main types of leukemia, but there are other rare forms, these infants suffered from acute lymphoblastic leukemia (ALL). The average five-year survival rate in patients with Leukemia is 57% in the United States. The five-year survival rate for children under fifteen is ~ 60 to 85%.
New Therapies
As mentioned previously, researchers have identified new potential therapies based on targeting a molecular signature on the surface of the malignant B-cell. But re-engineering the cells from each single patient takes time and is expensive. What if T-cells targeting CD19+ B cells could be available as a universal type? They could be administered to any patient and might also be altered to decrease the cytokine response, so they'd be safer to use.
To take on this approach, two genetic modifications were made. The first changed the antigen signatures of the T-cell itself. The authors used the TALEN technique to disrupt CD52 in cells obtained from a non-compatible (non-HLA match, meaning different cell-surface signatures) donor. Patients undergoing these T-cell therapies first undergo an immunodepletion treatment to suppress numbers of existing T-cells. This is done using an antibody-based chemotherapy agent that targets the CD52 receptor. This first deletion ensures that the therapeutic cells targeting CD19 malignant B cells would not be eliminated by the treatment.
The second modification using TALEN, targeted the HLA signature of the cells that would stimulate the recipient's immune system from attacking it. The TALEN method introduced a deletion in a region of the T-cell receptor α chain, so that the T-cell receptor would be incomplete and evade detection from the patient's immune system.
The therapy was not without risk. While the HLA antigens were absent from most cells in the therapy, some were still present, so there was a risk of inducing rejection along with its potential complications. Both patients showed mild symptoms, and they were successfully were treated with minor interventions. The TALEN technique works because it introduces chromosome breaks in the target gene. It is possible that off-site breaks could have occurred as well. The other risk was the cytokine response once CD19-attacking cells are introduced to the body.
The breakthrough of this work was simply that a known effective therapy was now being administered from a universal donor cell type. A number of companies including Cellectis, Cell Medica, Fate Therapeutics, Kite Therapeutics, and Regeneron have been developing universal donor techniques that allow the bioengineered T-cells from donors other than self-donation to be possible. This cuts down on the expense, time, and logistics, making the product more readily available to the patient.
The work by Qasim et al is important because it takes an exciting new therapy and then uses gene editing techniques to make it applicable from a universal donor. The hope is that these two treated infants live long, healthy lives, and that they will be remembered as pioneers in a revolutionary area of medicine.
Qasim et la., Molecular remission of infant B-ALL after infusion of universal TALEN gene-edited CAR T cells, Science, Jan 25, 2017. Vol. 9, Issue 374, DOI: 10.1126/scitranslmed.aaj201
Monday, January 30, 2017
Toxic Rock Syndrome
Keeping the Lapidary Arts Out of Your Yoni
As time goes on, Gwyneth Paltrow is recognized less and less for her acting prowess, and more and more for her rotten health advice. Her latest? Urging women to vaginally insert a jade egg, a stone the size of a ping-pong ball, and hold it there. All day. Every day. Yet another new spin on the Amish rock tumbler.
The claim is that the $66 jade egg (sold out) clutched in the birth canal can "increase vaginal muscle tone, hormonal balance and feminine energy in general."
The claims are enumerated in depth on the goop.com website, accompanied by the article, Jade Eggs for Your Yoni. She suggests that holding the egg in a hypo-utero position can improve everything from kidney function to "invigorating your life force."
Is it really good practice to get intimate with a stone? Certain feminine products were implicated in what was known as Toxic Shock Syndrome during the late 1970's. It is an acute disorder characterized by a spectrum of symptoms brought about by bacterial colonization from bacteria that emit toxic compounds that attack body tissues. These bacteria include Staphlococcus aureus and Streptococcus pyrogenenes, among others. The condition can rapidly lead to coma and death, unless treated with aggressive courses of antibiotics.
Dr. Jen Gunter, an actual OB/GYN at Kaiser Permanente in San Francisco suggests that clutching any stone in the nether-regions is perhaps not a wise idea, as she says, ""I would like to point out that your pelvic floor muscles are not meant to contract continuously."
She continues, "In fact, it is quite difficult to isolate your pelvic floor while walking so many women could actually clench other muscles to keep the egg inside."
Apparently this physician does not endorse Gwyneth's recommendation.
Paltrow suggests the insertion of the jade egg, a curious choice for a particular stone. It seems like its smooth edges could lead to hazardous misplacement, only exacerbating the other issues with bacteria or pelvic disease. But her $66 stone has a small hole for a retrieval leash, or perhaps just a place for S. aureus to colonize.
If you are in the market for a crotch stone, perhaps opt for a hunk of shale or quartz. Flat edges and jagged crests ensure precise immobile placement, and serve as a not-so-gentle reminder that you are benefitting from the invasive spiritual cleansing that only clutching a piece of the earth's crust can give you.
The take home message — we should not trust Hollywood's B-list with gynecological advice. Don't put gravel into your vagina or any body orifice for that matter. Unless you are a pigeon, then you get a pass.
Apparently the jade eggs are flying off the shelves, as they are 'sold out' at the moment. It is a sad time to think of the thousands (millions?) that have turned to a celebrity for health advice. Not only have they lost a few dollars, they may have endangered their own reproductive health and perhaps even their lives.
Monday, January 16, 2017
Jeff Goldblum
yippee...more fun vaccine talk
Fun Fact: We currently have eradicated one disease; in 1980 the CDC reported smallpox to be eradicated.
New England Journal of Medicine http://www.nejm.org/doi/full/10.1056/NEJMms1215400
According to a report from the World Health Organization 2011:
· 7.6 million children under the age of five die every year, according to 2010 figures
· Over two-thirds of these early child deaths are due to conditions that could be prevented or treated with access to simple, affordable interventions.
· Approximately 40% of child deaths occur in infants under one month old.
· Children in low-income countries are nearly 18 times more likely to die before the age of five than children in high-income countries.
· Vaccines are cost-effective and life-saving.
· In 2010, 109 million children were immunized with three doses of tetanus, diphtheria and pertussis vaccine
· Vaccines prevent 2.5 million deaths every year in all age groups
Some children die from a vaccine preventable disease, and many others have to live with the effects of a vaccine preventable disease.
We have two other diseases that are on the docket for eradication, one you have no doubt heard of: Polio, which reported cases fewer than 250 in 2012, compared to 650 cases in 2011 globally. The other is one that does not affect us because we have wonderful drinking water, aren't we lucky? It's called Guinea worm disease and is only found in certain areas of Africa.
We are seeing a recurrence of diseases that we have vaccines for, which tells us that people are not getting immunized---for personal reasons, or just because there is no access to medical treatment for prevention. In some communities we are finding a high incidence of a little creep called Bordetella pertussis, it's the bacterium that causes whooping cough. In 2010, California saw 9,120 cases of whooping cough, more than any year since the
Herd immunity works logically, if the masses are immunized, those few that are not immunized have the protection from the disease causing pathogens because the pathogens are being isolated. But the people not getting immunized are starting to surpass the people that are immunized in some communities, therefore the anti-vaxxers are no longer protected by the pathogens that cause the disease.
Herd immunity works logically, if the masses are immunized, those few that are not immunized have the protection from the disease causing pathogens because the pathogens are being isolated. But the people not getting immunized are starting to surpass the people that are immunized in some communities, therefore the anti-vaxxers are no longer protected by the pathogens that cause the disease.
In all of this time of treating diseases, viruses, bacteria, etc., we have managed to rid our world of a disease. I hope this sounds as amazing to you as it does to me. Sadly to anti-vaxxers the glass is half-empty. They feel that after all of this time of medical intervention, we have only been successful in ridding ourselves of one disease. They are looking at the finish line (and the game is not even close to being over) and are not looking at what is going on in the game.
But there are those that yearn for good ole yesteryear, where people had a dozen kids and only a few made it into adulthood, and we died before the age of 40.
Works Cited:
Willem G. van Panhuis, M.D., Ph.D., John Grefenstette, Ph.D., Su Yon Jung, Ph.D., Nian Shong Chok, M.Sc., Anne Cross, M.L.I.S., Heather Eng, B.A., Bruce Y. Lee, M.D., Vladimir Zadorozhny, Ph.D., Shawn Brown, Ph.D., Derek Cummings, Ph.D., M.P.H., and Donald S. Burke, M.D.
N Engl J Med 2013; 369:2152-2158 November 28, 2013 DOI: 10.1056/NEJMms1215400
WHO. (2011). Children: Reducing Mortality. Retrieved January 2012, from World Health Organization: http://www.who.int/mediacentre/factsheets/fs178/en/index.html
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Writing a novel isn't easy. It takes knowledge, patience, and time. It takes research. Research is a really dangerous thing. I've seen, time and time again, writers who get so caught up in researching for their novel that they never get around to writing their novel. This is both a guide to condensing researching and a set of tricks and tips you can use to avoid falling into the dangerous black hole of research.
What is Research?
Research is the act of purposefully trying to learn about a subject. It's the art of getting your facts right.
Knowledge about a subject helps add reality to your novel. It helps you suspend disbelief when you do, purposefully, break the rules of science. Most people won't be able to distinguish fact from fiction when your fiction is full of facts.
Research is an extremely dangerous trap.
When to Stop Researching
This is a 'it depends' answer. My general rule of thumb, however, is to stop researching when I have the absolute bare minimum to bullshit the subject. That's right. When I'm drafting, I bullshit as much as possible. I have a hypothermia patient? I go to wikipedia, read the page, and bullshit it. I have someone who is suffering from blood loss? I look it up on the google. More accurately, I look up the conditions for someone to die from blood loss, and I look up the normal conditions of a person with normal blood levels. I look up the symptoms of blood loss, and I roll with the punches.
Each one of these subjects takes me no more than ten or twenty minutes. I take notes on the type of research I need.
Fix the Errors Later
That's right. Bullshitting your research is fine in the rough draft. Bullshit your heart out. Get the draft on paper.
Fix the errors later. That's what editing is for.
You should research the absolute minimum to write your draft zero, which is what NaNoWriMo is all about — it's all about writing that draft zero.
You can fix the errors and do you research when you decide to seriously pursue the novel. Then you might spend hours on the symptoms of hypothermia to make certain you get it right.
A Note about the Rule of Thumbs…
… did you know that most people believe the rule of thumb was coined as a method of men avoiding charges of abuse from beating their wives and children? If a lash mark was smaller than the width of a thumb, it fell under the rule of thumb, and did not count as abuse.
This is an example of research in application. No one actually knows the origin of the rule of thumbs, and it was never officially in any law that a man could use his thumb as a method of determining whether or not his corrections of his wife or children was legal.
It makes for a nice story, though.
The interesting thing about my knowledge of the rule of thumbs? It took me less than five minutes to obtain, and another two to three minutes to verify the source.
Research doesn't need to be time consuming. It can be condensed. It can, when you're working on a draft zero, be rushed.
So how do I research efficiently?
It takes knowledge to seek knowledge. Some of you might be wincing right now. I don't blame you. Until I figured out that a jack of all trades was better than an expert in one subset of knowledge, research got to be a lot easier. I'm not specialized in much of anything. I know a little more about horses than the average joe, because I really love horses, but I am not a super star on any subject.
I have a broad scope of general knowledge, however. Most of it I picked up from working as a freelance author. I had to be flexible and learn a lot, because I wrote about something new each and every day.
When you first start out, it might feel like you're attempting to climb Mt. Everest. (29,029 feet above sea level, tallest mountain in the world, located in the Himalayas. Its summit marks the international border between China and Nepal. 26,000+ feet is considered the death zone.)
It took three minutes to get that information on Everest. I googled "Mt. Everest", opened up wikipedia, and also checked out some other relevant websites.
I picked out the most important details, noted them, and went on my way. Now I know that if I want my characters to be at high risk of death, the closer to the 26,000 point they reach on the mountain, the more likely they are to die. That's conjecture. I made an assumption due to the naming of the zone, and the probability of death as climbers reach that point.
It's an aptly named zone. Those who haven't spent 40-60 days of acclimation in mountainous terrains can die up there, and fast. Wikipedia says the time to lose consciousness in the death zone is 2-3 minutes.
Everest, you're mean.
Reading about the death zone took an extra three minutes, including the write up.
Thus the nature of the research trap. I wanted to learn the basics about Mt. Everest, so I had a look. Then, I saw something interesting: The Death Zone.
So, of course I started reading about the Death Zone. Because really, that just sounds really interesting.
I wasted three minutes. I doubled my research time, all because I kept reading about something I did not need to keep reading about.
And that goes against what I said before: Knowledge is needed to search for knowledge. If this is the case, why is reading about something I didn't need to keep reading about bad?
In the case of the Death Zone, I didn't need to know the information about it. I just needed to know it existed. I learned it existed by looking at the table of contents in wikipedia.
Knowing something exists is knowledge. Because I know it exists, I know I can find it again. You need to know how to find things. In order to do that, you need to know enough of the basics to make associations.
Let's revisit the blood loss example.
I have a character who has been shot or injured, and is losing blood. I want to know how to write this character, particularly their reactions as the blood loss worsens.
A good starting point for this research is "Blood loss symptoms."
There are a hundred and ten different medical websites pointing out the common symptoms of blood loss. Most of them are trying to sell you drugs. Most of them may or may not be accurate. So, how do you know which sites to choose from?
.edu websites are a good start. Universities don't tend to put out false information. Government websites are also a good source, for that reason. (Or a well-known organization, such as WHO for disease research.)
If you can't find a .gov or .edu website, and wikipedia doesn't have an entry, check five or six medical sites and look at the common symptoms listed. They're probably close enough for you to bullshit the symptoms.
Mark it as needing research.
Move on.
But, let's say you need to research the rate of blood loss from a neck wound. Things just got a bit more complicated. Just how do you find that information out?
Try googling for bleeding to death. You'll learn a fancy new word: Exsanguination. It's so fancy my spellchecker isn't even recognizing it in my browser.
Sanguis is a word for blood. Ex is out of. Out of blood. Latin, you're great.
So, how do you get the information you need? Glance over the subject headings, to start with. Look for things that are relevant to your search. If you don't see something relevant, don't read it.
This saves time and helps to condense the research process. I always read the first paragraph or so of a wikipedia entry, because that is usually the condensed version of a subject.
Well, crap. Wikipedia doesn't have a time frame for exsanguination. Well, if you read the first paragraph, you'll have learned that major trauma relating to exsanguination involves veins and arteries. It is considered common knowledge that there is a major artery and vein in the neck.
Checking the animal slaughter and blood drain section of wikipedia reveals the jugular vein and the carotid artery as the major neck culprits.
But, why would I have checked the animal section in this case?
Humans are animals, and we share a lot of characteristics with animals. The entry is short, and when you're trying to research quickly, if there is any relation to what I'm looking for, it's worth a skim.
In this case, I was rewarded with the names of the major body parts in the neck relevant to my interests.
So, what next? Back to google. That's right, ignore the links to jugular veins and carotid arteries. Wikipedia is all about details of certain things, but when you start getting into lists of things like specific body parts that aren't organs, they're usually stub articles. Stub articles provide a very, very basic bit of information, and little else.
Try searching for death severed jugular vein.
After all, we're looking for how long it takes to die if your jugular vein is severed.
Scroll down. Look for answers. Lots of information here, but the ask.com answer is concise enough to be usable: Approximately two minutes.
You're done. Once again, mark it for confirmation during edits, using medical websites or asking someone who knows. Move on.
The cycle continues.
The more you participate in the process, the faster you'll become at picking out the really important details. You may bounce back and forth between google, wikipedia, and random websites. But, when you get used to the idea that you can't just research entire subjects and expect to get anything done, you'll be well on your way to writing a story that is close enough to accurate. Close enough to fool your readers.
That's what this is all about: Suspending disbelief.
Condensing your research is easy. Stop reading when you have finished gathering the specific bit of information you need. Go write instead.
And keep a journal or notepad handy so you can keep track of all of the things you may need to fix when you edit your novel.
Use October to practice the art of research, so when November comes, you're only spending 3-5 minutes doing research on a specific subject instead of ten, twenty, thirty, or even sixty minutes researching things you don't need to learn.


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Yesterday was the first day after a week I managed to get in the garden. There was a lot of rain last week so now plants are growing like crazy..but that's not all that grows...Weeds grow everywhere.
I wouldn't mind normal weeds but this year we have some crazy weird grass growing all around the garden
the worst part is that this grass has roots that go all the way to China. I can't get them out with hands. So there is nothing to do but to dig them out. It took me 4 hours just to clean all the paths in the garden. I didn't even touch the ones between plants. I was to afraid that I would pull out plants together with the grass.
In the end the only good thing was I had a bunch of grass for the bunnies :)
While I was digging I realized something. Scientists are talking about how ladybugs are disappearing from "don't know what's it's name island" they aren't disappearing. They just moved in my garden. It's unbelievable how many ladybugs we have this year
They even walk on me while doing woohoo :) ( yes I know to much Sims is damaging my brain )
After the rain I was finally able to get some potatoes from the last 2 rows. The soil there was like concrete till now so I went to get it before it turns to concrete again.
I've got a basket of nice big potatoes..I don't know how many there are I was too tired to weight them
Also I got a few of the smaller ones
And one that has a funny shape
While I was in the garden I also decided to get out all the parsnip
And as always tomatoes and cucumbers
There is still a lot of work in the garden but it was getting too hot to do it ..33°C (91F) at 12:00
All the time I was in the garden I had my little helper with me...watching my every move
- Home
- Recipes
- Crafts
- Vegetables
- Vegetable Encyclopedia
- Flowerpedia
Thursday, August 2, 2012
weeds weeds and more weeds
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TA Instruments NanoDSC
The NanoDSC enables investigation of the thermodynamic properties of our proteins in microvolume amounts of solution.
RT @cenmag : "Oh proton I feel your tug, central potential dip down pulling on me, but I'm not falling in deep, no that would break uncertai…2 days ago
RT @AsapSCIENCE : Abort! [ @ProPenComics ] https://t.co/n0bdL4ttXB1 week ago
This needs to change! "Why #women leave #academia and why #universities should be worried" https://t.co/8DbHIXaXp72 weeks ago
Congrats to @jkmontclare for giving the Plenary Address at @ATE Conference focusing on the "Power of Good #Mentors"! https://t.co/NqqN6Xt8mw3 weeks ago
@nyutandon #bs #ms #undergrad Nicole Schabel presents at the @AIChE meeting in Minnesota! #welldone #womeninSTEM https://t.co/iVXlVes2FK3 weeks ago


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henry2 architecture
Overviewhenry2 is a Linux cluster constructed using IBM and Lenovo blade servers. Blade servers are housed in blade chassis that each hold fourteen blades. The chassis provides power, cooling, management, and network connectivity for the blade servers. [Much of the design of IBM BladeCenter and IBM/Lenovo Flex System occured and occurs at IBM's and Lenovo's Research Triangle facilities. A number of the BladeCenter and Flex System design team members are graduates of NC State.]
|Image of IBM BladeCenter E chassis
|Diagram of BladeCenter chassis
When the central HPC service was initiated at NC State in 2003 a hardware strategy was adopted to incrementally grow the cluster rather than to periodically buy large monolithic clusters. The incremental approach was a better match with NC State's HPC funding and staffing. henry2 started with 64 nodes and 128 processors in 2003. Currently henry2 has 927 nodes and more than 9000 processor cores.
henry2 nodes are typically dual-socket Xeon blade servers. There are a mix of Xeon processor models. Nodes typically have 2-4GB of memory per processor core and a modest size disk drive that is used to hold the operating system, swap space, and a small local scratch space. Nodes have two Ethernet interfaces (mix of 1Gb and 10Gb). One of these interfaces is used for a private network connecting the compute nodes to the login nodes and to cluster storage resources. On compute nodes the second Gigabit Ethernet interface is used for a separate private network dedicated to message passing traffic. On login nodes the second interface is used for access to the campus network.
Typical compute node chassis network connections use a 10Gb
Ethernet link for the private HPC network connecting computed nodes to login
nodes and storage and four aggregated Gigabit Ethernet links for the message
passing network.
henry2 cluster is assembled using several core Ethernet switches - one dedicated for message passing traffic and the rest for other network connections needed in the cluster. The message passing switch can provide up to 384 Gigabit Ethernet ports and can support up to 96 chassis aggregating four links per chassis. Therefore, the current network architecture will support about 1344 nodes (this is an approximate number because some of the chassis have separate low latency networks and have a single Gigabit Ethernet link to the core message passing switch).
Communications between compute nodes is non-uniform due to henry2's network architecture. Nodes within a single chassis can communicate with no bandwidth restriction (full gigabit or 10 gigabit each direction) via chassis Ethernet switches.
|Typical network connections between compute node chassis
Communications between blades in different chassis is limited to 4 gigabits per second in each direction. So for example if eight nodes in one chassis were exchanging messages with eight nodes in another chassis they could each potentially have a gigabit per second of traffic in each direction for total of 8 gigabits of data per second in each direction. However the henry2 network architecutre would limit the achievable communication rate to four gigabits per second in each direction. The communication could also be impacted by message passing network traffic from the other blades in each chassis that share the aggregated links.
In addition to the bandwitdh effects of the network design there are also latency effects. Within a chassis messages have a single switch to traverse. For communications between chassis there are three switches that must be traversed (the chassis switch in each chassis plus the core switch). Each network switch adds some additional time it takes the message to reach its destination.
StorageThere are three types of file systems on the henry2 cluster. However only two types are generally accessed by users: Network File Systems (NFS) and General Parallel File Systems (GPFS). Directories such as /home and /usr/local are NFS mounted file systems. /gpfs_share is a GPFS file system.
File systems on henry2 use a variety of disk arrays typically fibre channel attached to file servers. In general, blade servers are used for file servers on henry2. File server blades are located in chassis with an additional IO module that provides fibre channel connections to each blade server.
NFS file systems on henry2 typically have a single file server with fibre channel connection to a disk array. NFS tends to perform poorly when accessed from a large number of nodes concurrently. The typical henry2 configuration of NFS has several bottlenecks including single NFS server and single fibre channel connection to disk array.
|Typical henry2 NFS configuration
GPFS provides capabilities to support concurrent parallel access of a single file from multiple nodes. However, GPFS tends to not perform well for accessing large numbers of small files.
|henry2 GPFS configuration for /gpfs_share
GPFS as configured on henry2 uses multiple servers that create network shared disks (NSDs). These NSDs create a file system that is mounted on each henry2 login and compute node. GPFS IO operations are cached on the local node and then synchronized with the file system. Multiple NSD servers are able to support more concurrent use and also provide resiliency against failures.
Last modified: October 23 2016 13:24:27


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I wrote about this awhile back and found bit and pieces of the old post. Last night getting ready to go out I had similar feelings so I'm reposting.
Why is it one day I can catch a glimpse of myself and see all that I accomplished? 70lbs gone, the slender body I always dreamed of having since about age 12 and self-confidence and sense of determination that I can do anything I set my mind to. But other days I catch that same glimpse, it can be the next day or maybe even an hour after the first glimpse and I see a completely different body. Every flaw magnified, I see thickness, I feel vulnerable, and the thought crosses my mind that it was all in vain. I swear the glimpse I see is the same body I had for most of my life.
Am I crazy? Well, some would say I am for other reasons. ;~)
In all seriousness, my logical mind knows that the latter scenario is preposterous but when this happens it does mess with your attitude, motivation and confidence that day.
I can't be the only one that feels this way, am I?
Note: I would give credit for the picture but I honestly don't remember were I found it. Sorry.


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Credit Advice
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There is some disconnect here... Do you mean Fair Credit Reporting Act? Now if it dose meet the requirements for FCRA? Then it mean it's can be reported and be on your credit report. Collection accounts do get sold often, when that happens? The old CA would/need to remove that account from your report, so the new CA might report if they chose to, each new collection agency might report the new "open" date, as thats the date they received the collection authority on that debt. However, it won't affect the 7 1/2 years of reportable period, because it goes by the Date Of First Delinquency and not the open date or any other dates for that matter and nothing can extended or restart that 7 years plus 180 days running on your report.
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Retailers are weighing the attraction of national brands against the growing demand for value-priced merchandise in their nonfood baby care product sets.
While in many stores the baby care customer will not skimp on products for their child, others still face hard economic realities and buy the lower-priced items, retailers said. Among the trends mentioned by nonfood executives interviewed at a recent General Merchandise Distributors Council conference were a growing sophistication in


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It is a treat to get a short story in Gin Blanco's world that isn't focused on Gin, but on her sexy brother, Finn. The events in this enovella happen immediately after the last book and it lets us into Finn's brain, which is not a very nice place to be at first because Finn is carrying along a truckload of misplaced guilt.
The biggest surprise of this enovella is the introduction of Stuart Mosley. He owns First Trust, the bank where Finn is employed and where Finn was tortured by his own mother. Mosely is a fantastic character and I could see him playing a bit of the Fletcher role moving forward, which would be good because the underworld is getting a lot more complicated for Gin and friends.


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pretty sure I posted this last year, may be wrong though!!!
Is that Selby ?
you might have posted something similar, but this is the one i took.
I hope there is a similar memorial at the place he escaped??
Here's a link to this photo. Just copy and paste!
Here is direct link of this photo
Copy and paste the code below (HTML):
Copy and paste the code below (BBCode):
[URL=https://www.arrse.co.uk/community/gallery/photos/4389/]4389[/URL] by [URL=https://www.arrse.co.uk/community/gallery/authors/quiller.1642/]quiller[/URL] on Army Rumour Service
Separate names with a comma.