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Non-Invasive Glucose Monitoring Patent Landscape - The global glucose monitoring device market is estimated to reach $14 billion by 2019.
Sep 28, 2015, 09:10 ET from Research and Markets
DUBLIN, Sept. 28, 2015 /PRNewswire/ --
Research and Markets (http://www.researchandmarkets.com/research/zkjjjs/noninvasive) has announced the addition of the "Non-Invasive Glucose Monitoring Patent Landscape" report to their offering.
To this date, the conventional technique to measure glucose still involves drawing blood (finger pricking), which can cause pain and discomfort for the patient. Hence, the need to find a non-invasive technique to monitor glucose. Many companies have tried to develop non-invasive technology and device for glucose monitoring, but so far with no success.
A few devices had obtained approval from the authorities in the USA or Europe before being abandoned : GlucoWatch (Cygnus), Pendra (Pendragon Medical), NBM-200G (OrSense) or HG1-c (C8 MediSensors). Recently, Integrity Applications received the European CE Mark and launched its GlucoTrack DF-F device late 2014 in Europe. While several minimally-invasive devices are now commercially available, bringing to the market a totally non-invasive device would represent a great change for the market and the diabetics.
The renewed IP interest for this topic observed recently shows the desire of players to overcome the same cause of failure faced in the last 3 decades, reliability and accuracy of the technology. The IP and the market for non-invasive monitoring of glucose are driven by the ever increasing diabetic population around the world as well as the recent sizeable democratization of wearable sensors for health monitoring. The spectrum of technologies investigated to monitor glucose non-invasively is very broad. Spectrometry is the most trendy technology. Spectrometry regroups various techniques, but they don't all receive the same focus. The spectrum of sample targets studied to perform a non-invasive measurement is also really broad.
The detection of glucose level at the skin level or in the blood vessels are the most investigated. But techniques allowing a detection at the level of the eye are also considered and a new comer in the non-invasive glucose monitoring domain is investing mostly in this approach.
Key Topics
1. Introduction
2. Executive Summary
3. IP Overview
4. Main Patent Litigations
5. Non-Invasive Devices for Glucose Monitoring
6. Key Players
7. Conclusions
8. Annex
Companies Mentioned
- Abbott
- Animas Technologies
- Bayer Healthcare
- Cercacor
- Futrex
- Google
- InLight Solutions
- Integrity Applications
- Key Player Selection
- Masimo
- OrSense
- Panasonic
- Roche Diagnostics
- Samsung Electronics
- Sensys Medical
- Toshiba
For more information visit http://www.researchandmarkets.com/research/zkjjjs/noninvasive
Media Contact: Laura Wood , +353-1-481-1716, firstname.lastname@example.com
SOURCE Research and Markets


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U.S. Senate Passes Cybersecurity Information Sharing Act
(Bill available. Document #97-151119-013L.)
Cyber Threat Indicators
The bill, which was introduced in March by North Carolina Sen. Richard Burr, would require the director of National Intelligence (DNI), the Department...
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Grill-Roasted Pork Roast
3 lb Pork; center cut loin
1 tb Sage
1 ts Allspice
1 ts Coriander
1 ts Nutmeg
8 Peppercorns
1 tb Season salt
1 c Applesauce
1/2 c Brown sugar
Combine sage, allspice, coriander, nutmeg, peppercorns and season salt in food processor. Pulse until spices are combined.
Pat dry pork roast and press spices on fat cap of roast. Roast in dome bbq grill until 160F. internal temperature with indirect roasting. This can be done with a pan directly under the roast and coals placed on either side of pan. Roasting time should be about 90 minutes.
During the last 30 minutes of roasting, combine applesauce and brown sugar and coat top of roast. Continue roasting until internal temperature is 170F. Apply applesauce mixture until all is used.
Remove roast from grill and let set for 15 minutes before carving.
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UCSC East Field at 4:00 PM
To participate in the commencement ceremony, please contact Veronica Larkin.
Participants are required to wear cap & gown; the deadline to order regalia is April 22.
Order regalia through the bookstore by 4pm on April 28th (late charges apply thereafter).
The Bookstore's Commencement website has information about ordering regalia, as well as announcements and other commencement-related items.
J. Josh Guevara, Ph.D.
J. Guevara is the City of Santa Cruz Economic Development Manager and Municipal Broadband and Right-of-Way Manager, and Ph.D. in Literature. He specializes in business recruitment and retention, leading broadband internet development, and solving business issues while being an effective change agent within local government. Guevara has led the City of Santa Cruz's Fiber-to-the-Home efforts since 2014, establishing best practices to support a competitive internet marketplace while ensuring community benefits and social equity for fast and affordable internet to confront the digital divide. He spearheaded the creative strategy for ChooseSantaCruz.com, redefining what a local government website can achieve through an authentic brand, sustained by an in-house creative team. Directly connecting his 2012 UCSC Ph.D. in Literature with his research on the cultural studies of the bicycle, Guevara is helping to bring a 250-bike bike share system to the City of Santa Cruz by the summer of 2017 through a public-private partnership at no cost to taxpayers. Guevara earned his MA in Literature in 2009 from UCSC and his BA in Creative Writing from San Francisco State University in 2002, where he was the College of the Humanities Hood Recipient and the Creative Writing Honors Student of the Year. He lives with his wife and two sons on the Westside and provides professional headshots to local politicians, academics, and creatives at jguevara.photography.
On the Day of Commencement
* Plan to arrive with your regalia at the East Field between 3:15 and 3:30 pm.
* Tell friends and family to arrive at UCSC between 3:00 and 3:30 in order to find parking and get to the East Field. Because of the number of graduates, only students and faculty will be allowed in the East Field House. Please ask your family and friends to go directly to the seating area on the field.
* Wear comfortable clothing and shoes. Bring your sunglasses and sunscreen if you are sun sensitive - there is limited-to-no shade in the stands. The walk to the commencement site from the East Field House where the procession forms is about 1/4 mile. The late afternoon sun can be hot, and the ground uneven for those with high heels.
* We will have water stations available.
* Doctoral candidates should make sure that their chosen professor will be present for the hooding ceremony, or arrange for a substitute.
* Staff will help students and faculty with the line up and regalia.
* The East Field House will be locked shortly after the procession leaves; students should plan to leave their personal belongings with family, friends, or in their car.
* To be courteous and show respect for fellow graduates, students are expected to stay for the duration of the ceremony, and march out in the academic processional. Please silence cell phones, pagers, etc.
* The Baytree Book Store will provide a location next to the ceremony site where you can drop off your rented regalia after the ceremony.
Participation Instructions:
Assemble at the East Field House beginning at 3:15 pm.
Name cards: Outside the East Field House, go to one of the tables set up by degree to pick up the prepared name card, which will be used by the announcer to introduce you on stage. Included is a space for a phonetic spelling of your name to aid in pronouncing it correctly. Please review and make any changes you think necessary. Pens will be provided at the sign in tables.
Line-up and robing: Participants will line up by degree; look for the signs posted or ask a staff member to assist you. Masters candidates should wear the hood. PhD candidates should carry the hood. The tassel is placed on the left side of the mortarboard to signify the award of an undergraduate degree. It does not get moved to the right side at any time during the ceremony. Staff will be available to assist you.
Marching and seating: There will be two lines marching together to the seating area and then splitting to enter the bleachers on either side of the stage. Staff will direct you at strategic points in the processional.
Awarding degrees: Graduates will be called to the stage by degree: MA, MFA, MS, DMA and Ph.D. Students will proceed up the ramp to the stage and hand the name card to the announcer. (If your name is difficult to pronounce, you can pronounce it for them while you are waiting to cross.)
Master's candidates: When your name is called, walk to the center of the stage where the Chancellor will present you with a graduation certificate and shake hands; you then continue across the stage, down the stairs on the other side and return to your seat.
Hooding of Doctoral Candidates: The faculty member who is hooding you will join you on stage. Hand your hood to the Emcee, who will pass it on to the person hooding you. After the hooding, Chancellor Blumenthal will present you with your certificate and shake your hand. Proceed down the stairs and around the back of the stage to your seat.
Photographs: Professional photographers from Grad Images will take two pictures of each graduate. The first picture is taken at the bottom of the ramp before you go on stage, posed in front of a UCSC banner. The second picture is taken on stage as you receive your certificate or hood.
When all the students in each degree have been announced, Dean Miller will ask each group to rise and the Chancellor will announce the conferral of the degree. You will then be seated for the rest of the ceremony.
At the conclusion of the ceremony, the academic processional will leave the field in the following order: stage party, graduates, and faculty. Staff members will direct you.
Professional photographers from Grad Images will take two pictures of each graduate. The first picture is taken at the bottom of the ramp before you go on stage, posed in front of a UCSC banner. The second picture is taken on stage as you receive your certificate or hood. Proofs will be available 5 to 7 days after the ceremony.
Pre-register your own email address, as well as those of your friends and family email who would like to view and order your photos . Graduation Images will contact them just as soon as their photos are available for online viewing and ordering.
View your photos after the event at the Grad Images UCSC Custom Landing Page.
Seating and Parking
Seating is usually plentiful and no tickets are required. Some audience seating will be canopied; if you are sun sensitive, please plan to arrive early to secure shaded seats.
Parking for participants and guests will be available in the East Remote lot. Permits are not required.
Shuttle buses will be available to and from the East Field for those guests who prefer not to walk to the site.
Students, faculty or guests with hearing, sight or physical disabilities who may need special assistance should contact Veronica Larkin at email@example.com.
Hotel Reservations
Reserve early as hotels and motels fill up well in advance of commencement.
Dinner after the Ceremony: Students and their families wishing to eat at a local restaurant after the ceremony are urged to plan ahead and reserve early; make reservations for 7:00 PM or later. Be prepared for heavy traffic, both on the highway and surface streets.
For information on lodging and dining, visit the Santa Cruz County Conference & Visitors' Center http://www.scccvc.org
- Below are websites for the UC Santa Cruz campus.
Maps & Directions: http://www.ucsc.edu/visit/maps-directions.html
East Field: http://maps.ucsc.edu/content/east-field
1. Is there a limit to the number of guests who can come to commencement? NO
UC Santa Cruz recognizes that our students reach graduation day because of the support of many individuals. Therefore, we do not limit how many people each graduate can invite to the ceremony.
2. Do I need a parking pass? NO
Graduates and their families and guests should park at the East Remote Parking Lot below the East Field. A parking permit is not required, but we encourage carpooling to reduce traffic in and around campus. A shuttle service will be available to take you directly to the Field, or you may walk the distance of about a 1/3 of a mile. Shuttles will also run after the ceremony.
3. Is the ceremony site accessible for those with disabilities? YES
Graduation parking is in the East Remote Parking Lot. This lot will be served by campus shuttles for those who cannot or do not wish to make the short walk to the ceremony. These shuttles may not be wheelchair accessible. Graduates or their guests who have special parking needs or who require a wheelchair-lift-equipped shuttle should contact Veronica Larkin (firstname.lastname@example.com) for instructions. All shuttles drop off at the same place on the East Field. Distance from the drop off point to the seating area is about 100 yards.
4. How long is the ceremony? Approximately 1-½ hours
The ceremony is scheduled to begin promptly at 4:00 p.m. and last about an hour and a half. If you are considering dinner afterwards, it is never too soon to make your reservations for this popular weekend.
5. Will I be able to get close to the stage to take a picture as my student walks across? NO
Only graduates and participating faculty are allowed around the stage area during the ceremony. As in past years, Grd Images, a professional commercial photographer, has been contracted to take individual photographs of the graduates as each receives a commemorative certificate. Within 10 days after graduation, students will receive a "proof," at no cost or obligation to buy.
6. Is there a reception afterwards? NO
As there are department events as well as private celebrations planned for shortly after the ceremony, the Graduate Division is not sponsoring a reception after the commencement.
7. Is smoking allowed on campus? NO
A friendly reminder to our guests that, as of January 1, 2014, the University of California is a Smoke & Tobacco Free environment.
Regalia & Robing
If a student registered for commencement and listed you as a "hooder" you will receive an email from the graduate division.
Regalia Rental: You are responsible for ordering your own regalia. Please see the Bookstore web site for details.
Assembly & Marching
- Assemble at the East Field House beginning at 3:30 p.m. At the Field House, your student will pick up a pre-printed card with his or her name and major, as well as your name, which will be used to introduce you. Staff will be available to assist with regalia and answer any questions. The student-faculty procession will leave the East Field House at approximately 3:55 p.m.
- Water stations will be available for all participants at the gym and behind the stage. Please bring your own sunscreen.
- The procession will be led by the Chair of the Academic Senate; followed by the Stage Party, Faculty and Graduates. Faculty other than the Stage Party will be seated in the front rows of the audience. Staff will direct you to your seats.
Doctoral students will be lined up by department. As you face the stage, the graduates will enter the stage from the right and the faculty will come on stage using the stairs on the left side. Approach the stage shortly before your student's turn and join him/her center stage. Student will hand the hood to Prof. Brenneis, who will make sure it is open and facing the correct way and pass it to you. Hood the student as your name is read. The student will then proceed over to the Chancellor to receive a handshake and certificate; then you both exit by the stairs. Please return to your seat right away to avoid congestion around the stage area.
If you are hooding more than one candidate, stay on stage and follow the same procedure for each student; leave the stage when all your students have been hooded.
If you are one of two faculty who will be hooding a student, we suggest that you both discuss with the student ahead of time how they wish the hooding to be arranged.
Regalia Rental
2017 Commencement Speaker
Student Information
General Information for Students, Faculty and Guests
Guest & Visitor FAQ's
Faculty Participants
*Separate commencement ceremonies will be held on the weekend of June 16-18 at UCSC's ten colleges, the School of Engineering, and the Division of Graduate Studies.
Students who earned graduate degrees since the 2016 Commencement Ceremony are invited to participate.


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Who's ready for more fall-like temperatures? Well, weather you're ready or not, you need to get prepared for some much cooler weather this weekend. We still have one more very warm day today, so if you like to 80s then get out and enjoy this afternoon.
Highs today will be 10-12 degrees above average. A strong cold front will move through tonight/early Friday morning, bringing a small chance for a shower and some much cooler air.
We could see a spotty shower or two for the Friday morning commute but skies will clear quickly into the afternoon and temps will start dropping. It will still feel nice on Friday afternoon with highs still in the low to mid 70s.
The colder air will continue to filter in Friday night into Saturday morning. Highs on Saturday will remain in the 60s and then low Saturday night/Sunday morning will drop a little more, possible into the upper 30s for some areas inland.
We will start a small warming trend into the start of next week but high pressure to our north will keep us sunny and cooler, but still around average.


text:
Traveling Luck for Welcome, Wyoming, United States
Where is Welcome?What's around Welcome?
Wikipedia near Welcome
Where to stay near Welcome
The timezone in Welcome is America/Rankin_Inlet
Sunrise at 08:02 and Sunset at 17:22. It's Dark
Latitude. 44.3731°, Longitude. -104.0692°
Weather near Welcome; Report from HULETT MUNI, null 59.9km away
Weather :
Temperature: 12°C / 54°F
Wind: 10.4km/h Southwest
Cloud: Sky Clear
Weather :
Temperature: 12°C / 54°F
Wind: 10.4km/h Southwest
Cloud: Sky Clear
Satellite map around Welcome
Loading map of Welcome and it's surroudings
Geographic features & Photographs around Welcome, in Wyoming, United States
- valley;
- an elongated depression usually traversed by a stream.
- Lincoln Gulch (1.4km)
- Mallory Gulch (1.4km)
- Mallory Gulch (1.5km)
- Roena Gulch (1.9km)
- Cummins Gulch (2.5km)
- Spottedtrail Gulch (2.5km)
- Shirttail Gulch (2.6km)
- Centennial Gulch (3.2km)
- Negro Gulch (3.3km)
- Wyoming Gulch (4.5km)
- Ladyfinger Gulch (4.8km)
- Bonanza Gulch (4.9km)
- Chicago Gulch (5.8km)
- Pole Cabin Gulch (6km)
- mine(s);
- a site where mineral ores are extracted from the ground by excavating surface pits and subterranean passages.
- Sand Creek Mine (1.2km)
- Giant Mine (1.9km)
- Rusty Number 9 Mine (1.9km)
- Tinton Mine (2km)
- Giant-Volney Mine (2km)
- Eureka Number Mine (2.2km)
- Bear Gulch Placer Mine (2.4km)
- Spearfish and Centaur Mine (2.7km)
- Filmore Mine (3.3km)
- Bull Hill Mine (3.3km)
- Keenan Properties Mine (3.4km)
- mountain;
- an elevation standing high above the surrounding area with small summit area, steep slopes and local relief of 300m or more.
- Mineral Hill (1km)
- Negro Hill (1.8km)
- Sunshine Hill (2km)
- Negro Hill (2.2km)
- Grandview Hill (2.5km)
- Bull Hill (3.1km)
- Beartown Hill (4.4km)
- Green Hill (5.2km)
- Old Baldy Mountain (5.4km)
- Lytle Hill (5.8km)
- spring(s);
- a place where ground water flows naturally out of the ground.
- Pole Cabin Spring (2.2km)
- Centennial Spring (2.3km)
- Lone Grave Spring (3.3km)
- Guidinger Spring (4.2km)
- Idol Spring (4.2km)
- Potato Spring (5.3km)
- Rattlesnake Spring Number 1 (5.9km)
- Christianson Spring (6.2km)
- Local Feature;
- A Nearby feature worthy of being marked on a map..
- Welcome (0km)
- Conners Rock (4.1km)
- Sager Ranch (4.5km)
- Seeley Ranch (4.5km)
- Lap Circle Ranch (5.4km)
- Mathews Ranch (5.5km)
- Bear Gulch I (historical) (6.1km)
Accommodation around Welcome
- stream;
- a body of running water moving to a lower level in a channel on land.
- Middle Beaver Creek (4.6km)
- South Beaver Creek (5km)
- North Beaver Creek (5km)
- Lightning Creek (5km)
- Potato Creek (6.2km)
- populated place;
- a city, town, village, or other agglomeration of buildings where people live and work.
- Tinton (2.2km)
- Sand Creek Crossing (5.8km)
- Beaver Crossing (6.3km)
- ridge(s);
- a long narrow elevation with steep sides, and a more or less continuous crest.
- Cement Ridge (1.8km)
- lake;
- a large inland body of standing water.
- Bear Lake (6km)
- cemetery;
- a burial place or ground.
- Bear Gulch Cemetery (3.6km)
Wikipedia entries close to
- North Spearfish, South Dakota city city o
- Spearfish, South Dakota city city o
- Central City, South Dakota city city o
- Lead, South Dakota city city o
- Sundance, Wyoming city city o
- Deadwood (South Dakota) city city m
- Saint Onge, South Dakota city city o
- Whitewood, South Dakota city city o
- Belle Fourche, South Dakota city city o
- Black Hills landmark landmark
- Sturgis, South Dakota city city o
- Fruitdale, South Dakota city city o
- Nemo, South Dakota city city o
- Osage, Wyoming city city o
- Nisland, South Dakota city city o
- Hulett, Wyoming city city o
Airports close to Welcome
Ellsworth afb(RCA), Rapid city, Usa (95km)


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Knowing the Real Jesus: A 30-Day Devotional (Real Life . . . Real Questions . . . Real Jesus)
Knowing the Real Jesus: A 30-Day Devotional challenges youth to know Jesus as God, man, Savior, and King.
The Real Life . . . Real Questions . . . Real Jesus series brings teens and young adults up close and personal with Jesus and his place in their daily lives. Each session includes Real Xpressions stories of young adults followed by a Real Question that has a Real Answer. Each study ends with Real You an opportunity to apply this truth from Jesus to your own life.
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The Florida Legislature must submit a revised map of all 27 congressional districts by Aug. 15 and propose a special election to fill those seats, a judge ruled Friday.
The decision by Circuit Court Judge Terry Lewis is part of the latest battle over the state's redistricting. Lewis ruled July 10 that the state's congressional redistricting maps are invalid and declared that the way two of the state's districts were drawn was unconstitutional.
The current ruling throws the issue of all of the districts into the hands of the Legislature, which will have to schedule a special session to approve the new maps. Lawmakers have the option, however, to appeal Lewis' timetable to a higher court.
In Friday's ruling, Lewis set the deadline for the new map for no later than noon Aug. 15 and ordered state officials to set a proposed special election schedule as well. Parties have until Aug. 18 to present objections to the new map and oral arguments are set for Aug. 20 if needed.
The ruling against the districts complicates the 2014 congressional elections scheduled for November. In his six-page ruling, Lewis notes that the new map is a first step and that a special election might be possible, though there are other connected legal issues, including whether he would retain jurisdiction over the issue.
The judge also said he had no choice at this point but to seek some remedy.
"The cure should not be worse for the patient than the illness,'' Lewis wrote. "To develop a new map and hold a special election for some congressional representatives would cost more money, would place additional burdens on our election officials and might confuse some voters. On the other hand, to do nothing, when you could, means that you lessen the ability of many citizens to fairly elect representatives of their choice -- which is the effect of political gerrymandered districts."
The League of Women Voters, which joined with other voters groups to file the original lawsuit, said it was pleased.
"This is a champagne moment for Florida voters, who have waited too long for fairly drawn congressional districts," Deirdre Macnab, president of the League of Women Voters of Florida, said in a statement. "Per his ruling, Judge Lewis has laid out a path that will allow all Florida voters, for the first time in decades, to elect their representatives in fair and constitutional districts."
The groups, which challenged the current districting, argued that it violated the Fair Districts rules approved by voters in 2010. After a 13-day trial, Lewis ruled that the Republican-controlled Legislature allowed "improper partisan intent" to infiltrate the redistricting process.
Follow @latimesmuskal for national news


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Max's Victory Trailer (2011)
01 October 2011 Comedy 108 mins
Worker Maks Bigec decides to take things in his own hands when he hears that his factory will be closed. He takes the factory director as a hostage and demands that the state should reopen the factory.
Watch the official Max's Victory 2011 trailer in HD below or find more Max's Victory videos on Vidimovie.


text:
Palin: 'WikiLeaks Fiasco' All Obama's Fault
November 29, 2010
(ChattahBox Politico News)— In between peddling copies of her new ghost-written book, Sarah Palin found the time today to take to Twitter and Facebook to blame the leaks of stolen diplomatic cables on President Obama's "incompetent handling of this whole fiasco." On Twitter, the former half-term governor also scored a plug of her book, while also wondering why Obama couldn't have just sued to stop WikiLeaks like she did with Gawker's posting of advance passages of her book. On Facebook, Palin slammed Obama for not hunting down WikiLeaks's founder Julian Assange and taking him out, the same way "we pursue al Qaeda." Good grief. The conspicuously unintelligent realty TV star and Fox News contributor needs to stick with clubbing halibut to death and shooting stuff, instead of shooting off her mouth to reflexively blame President Obama for everything, just because.
First Palin tweeted: "Inexplicable: I recently won in court to stop my book "America by Heart" from being leaked, but US Govt can't stop Wikileaks' treasonous act?"
Mother Jones' David Corn quickly disposes of Palin's just sue WikiLeaks like I did Gawker idiocy, noting the different legal standards and completely opposite situations.
"Inexplicable? Does she not understand the difference between apples and nuclear reactors? The two instances she links have little in common. In the case of her book, she managed to get a judge to order Gawker to take down a post showing portions of her book after the website had put them up," writes Corn.
Corn goes on to school Palin on the legal standard of "prior restraint" derived from the famous Pentagon Papers case. "The guiding principle here: the government does not have the right to impose prior restraint on the media," said Corn.
In Palin's Facebook rant, she asked why Assange wasn't treated like a terrorist and hunted down, captured and waterboarded, or something.
"Assange is not a "journalist," any more than the "editor" of al Qaeda's new English-language magazine Inspire is a "journalist." He is an anti-American operative with blood on his hands. His past posting of classified documents revealed the identity of more than 100 Afghan sources to the Taliban. Why was he not pursued with the same urgency we pursue al Qaeda and Taliban leaders?"
Palin further blamed Obama for not coordinating an international cyber attack of WikiLeaks' websites.
"What if any diplomatic pressure was brought to bear on NATO, EU, and other allies to disrupt Wikileaks' technical infrastructure? Did we use all the cyber tools at our disposal to permanently dismantle Wikileaks? Were individuals working for Wikileaks on these document leaks investigated? Shouldn't they at least have had their financial assets frozen just as we do to individuals who provide material support for terrorist organizations?"
It's hard to take anything Palin says seriously on even inconsequential issues, but when a real crisis hits or she tries to tackle something of substance, her astonishing lack of intelligence and reflexive hate for Obama is a chilling reminder that this vapid woman plans to run for president.
2 Responses to "Palin: 'WikiLeaks Fiasco' All Obama's Fault"
Salvatore Bucca on
December 3rd, 2010 5:57 pm
Sarah is absolutely right. How is it that you Obama defenders turn a blind eye to him disgracing our country, putting down the USA and weakening our defenses ? He could have and should have stopped that leak, but is now silent about it.
Who side are you on ?
dicksanchez on
December 11th, 2010 4:42 pm
Hard to take an ideologue seriously when you obviously are prejudiced against her. She had more experience governing than Obama as well as having actually run a business. Her values are more in line with the American dream than any of our current politicians.
That doesn't qualify her as the best candidate, just better than all we have now, and you could have reported better or at least more fairly.
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text:
First it was Missouri, then Kansas State, then Iowa. But in the end Jerrill Humphrey won't be going too far from home.
This weekend Humphrey, 6-foot-4, 190 pounds with 4.5 speed took his official visit to Missouri.
"It went good," said Richie, Jerrill's uncle who was very involved with the recruiting. "It was a good trip and Jerrill committed to Missouri."
Article Continues Below
Humphrey has been described by some college coaches as having Randy Moss-type talent had a final three of Missouri, Kansas State, and Iowa.


text:
Rosset-Morgan Books, Nov 25, 1997 - Fiction - 192 pages
Billy "the Gimp" describes life among the people who frequent the Times Square peep shows in Manhattan
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3 pages matching bondage magazines in this book
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text:
Elizabeth became queen in 1952 after the
premature death of her father, King George VI.
Elizabeth has overseen much prosperity and
development in the western world in what has
recently become the longest reign by any
English monarch, and is the current monarch
of the United Kingdom.
1 penny = 1/12 of a shilling
= 1/240 of a pound
The first Queen Elizabeth II NZ penny
was minted in 1953, and the last in 1965.
Dates not minted: 1966
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All Coin Values resource
NZ penny
Elizabeth II
1953 to 1965
What is a Queen Elizabeth II New Zealand penny worth?
Values, specifications, and images for New Zealand penny coins from
1953 to 1965.
The Queen Elizabeth II era New Zealand
penny obverse features the laureate bust
of young Elizabeth II, facing right.
The reverse shows a tui bird perched on
a blossoming kowhai branch.
The words 'NEW ZEALAND ONE PENNY'
surround the main design, with the
date below.
Value and spec information is sourced from various locations, including coin literature, coin dealers, resource websites, and asking price for online sales by reputable coin
dealers. All values are based on what you might expect to pay to buy a coin from a reputable dealer. Many factors affect value aside from grade. For the purposes of our
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text:
Image: Spiral of Complexity, Habitat
Caption: Moving up the complexity spiral to the levels of population and habitat, we trace the ecological interactions of V. cholerae populations in two distinct habitats: the human intestine and the aquatic environment.
Further description: Biocomplexity: A swirl of colors follows a black spiral. Following the path of the spiral are the following titles and images: Cosmos- picture of the cosmos, Planetary-picture of earth, Ecosystem-picture of a hurricane, Community-picture of an aerial view of a residential community, Population-picture of a forest, Habitat-picture of a single tree, Organism-picture of a seahorse, Organ-picture of a heart, Tissue-picture of human scar tissue, Cellular-picture of a cut-away cell showing the nucleus and chromosomes within, Molecular- picture of a swirling DNA strand with the DNA strand attachment within, and Atomic- picture of an atom cluster.
But everything is ghosted but the Biocomplexity title and the habitat tree.
Design by: NSF/S. Raimo
NSF funded: Yes
NSF permission to use: Yes
Government Image: Yes
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text:
Bruins winger Brad Marchand has been keeping a diary for ESPNBoston.com. In this playoff edition, he talks about how he predicted one of his goals, what he wants to say to the Penguins now, what to expect in the Stanley Cup finals and how the fans can help swing the momentum of a game. (As told to Louise K. Cornetta)
We're headed back to the Stanley Cup finals. This feeling will never get old. It's incredible. To have this opportunity at another shot at the Cup, there's no better feeling. We really want to embrace that and hopefully make the most of it.
How did we sweep the Penguins? It was tough. They have guys in Sidney Crosby, Evgeni Malkin and so many others who play hard, but our defense played incredible. Every single one of them did an incredible job battling down low and had good sticks. When the puck did get through, Tuukka [Rask] stepped up. The forwards did a good job of coming back hard. We wanted to make sure we had layers. We're happy with how everything went.
There were a few keys. We were prepared for this series. Tuukka has been incredible. He made all the right saves at the right time. He gave us momentum and kept us in it. We definitely wouldn't have won if he wasn't on our team.
Another key was we were fortunate to never trail in this series. Playing ahead is definitely a lot easier than playing from behind. It doesn't always work that way, but it's nice to play with the lead. We want to continue to do that.
As for my own play, I'd say I played well this series. We were all focused on doing our jobs. I just wanted to make sure I did my job when I was on the ice. I was able to assist on some important goals. The overtime one in Game 3 and the winner in Game 4 stand out. I actually called that I was going to score my second goal in Game 2. I had a feeling. I was talking to Thorty [Shawn Thornton] on the bench right after [Marc-Andre] Fleury came into the game. We were talking about where to shoot on him. I was like, "High glove. I'll show you." Thorty had a couple on him in there like that a couple of years ago. We wanted to shoot there, and I got lucky with the goal.
You might think now that the series is over I'd have a lot to say about guys like Matt Cooke and Brenden Morrow. So what do I have to say to them? Nothing. It's a hockey game. Everything that happens on the ice stays out there on the ice. We're not carrying any grudges. It's a job. At the end of the day, we want to respect our opponents. They played hard with great players who were out there trying to win like we were. I have nothing negative to say about anybody. Not to say I don't like talking when I'm out on the ice. You know how it goes. You're out there, and in the heat of the moment, things happen.
I know people will want to know how we feel about beating Pittsburgh with [Jarome] Iginla going there instead of here. Honestly, we're not worried about any single guy on that team. We're happy with the team we have. This is our team. We want to play with the guys we have. We're in the finals. Maybe if things had been different and things had changed up, we wouldn't be here.
Besides, we are happy to have Jaromir Jagr on this team. Have you discovered what a grinder he is? Especially with the assist on that game-winning goal in double overtime, he really dug out that puck to get it to me so I could pass it to Bergy [Patrice Bergeron]. He can do it all. He's one of the best players to ever play this game for a reason. He shows different parts of his game every night. We're glad he's on this team.
A moment that will always stand out from this series is the play when Soupy [Gregory Campbell] broke his leg but stayed on the ice for his shift during a penalty kill. He's a warrior. You can't say enough about him. The way he battled through that shot and kept playing was an incredible thing to see. Everyone can learn a lot from him in the way he plays and how much he cares about the team.
He will be missed, but I think everyone is going to step up and do his job. It's tough when guys go down. It's tough losing Soupy, who is an important player on our team. It just means that everyone has to step up a little more. Daugie [Kaspars Daugavins] did a great job coming in and played a great Game 4. Our depth makes us tough to play against.
Another moment that stands out from that double-overtime Game 3 is how incredible it is that Z [Zdeno Chara] and Seids [Dennis Seidenberg] played so many minutes. I will remember how tired I was after that game, and that's how much those guys play regularly. It's almost hard to believe.
Our team likes to play a physical game. A play maybe you didn't realize that made a difference and shows this was in Game 4 when Z made an incredible save with only a few seconds left on Malkin. I saw on the replay that there was a wide-open net and Z brought his hand around as he was on the ice to help stop it. That helped save the series right there and allowed us to move on to the Stanley Cup finals. Something like that is why he's such a great leader. We're lucky to have Z.
This team plays physical, especially at this point of the year. Guys want to lay their bodies on the line. We're willing to do that every night, like you saw with Soupy. It's just another example of how guys want to win and are willing to sacrifice their bodies for the team.
Next up is the Stanley Cup finals -- well, after a few days of rest. It will be nice to be able to regroup. It's good to kind of get our minds away from the rink for a few days. I hope we can do that. The two teams that are left in the Western Conference are tough opponents. We have to make sure we're prepared because they will be coming out very hard. They've both won the Stanley Cup recently, so they know how to win. It's going to be a battle.
Chicago and Los Angeles both have a lot of offensive weapons. They're both good teams. Obviously, Chicago is very offensive. It played great all year and had the most wins in the regular season. L.A. is kind of like how we were in 2011 in that we won at home, which is what it was doing up until Thursday night. The Kings are a great team too. It's always tough to go into another team's rink in the playoffs. The crowds are always incredible. Either way, it's not going to be easy. I know if we play the Kings we get home-ice advantage, but it really doesn't matter who we play. We're going to be prepared for either team and hope for the best.
I was mentioning how fans can make it tough on an opposing team, but they can really help the home team more than they may realize. In that double-overtime game, it is difficult because your body is so tired and you're starting to cramp up. That little momentum the crowd can give is the extra bit we need to keep pushing on. Fans can give us different momentum swings at different times, and that's enough to carry us to a victory. We're lucky to have the crowd that we do and the fan support around the city. We need you guys to keep going.


text:
Live pictures from Gastein
Webcam pictures from the Gastein valley. Have a direct look with the webcams in the region. Best quality and different views available.Show live pictures
The Spa hotels of Gastein open up worlds of relaxation, sports and luxury in one of the most beautiful regions of Austria. Spring, summer, autumn or winter, holiday or spa, you will always find relaxation plus a certain something that gives space for your individual wishes and needs to unfurl.
Dive in and be inspired, fire your imagination or just rest. Given the combination of wellness of the highest standard on the one hand, and sport, beauty, health, fun and food on the other hand, that turns a visit into an unforgettable experience for the whole family.
Feel free and do what you always wanted - that's our offering in one. From the moment you enter one of our Spa hotels and are welcomed by a friendly, eagle-eyed member of staff, that's the feel you have. Stop dreaming of a place that offers you an unforgettable break from everyday life. The Spa Hotels Gastein invite you to discover a world of relaxation - it lies in wait for you - and more!
Download the new magazine of the Thermenhotels Gastein or get it sent at home.To the magazine
All infos about Gastein on the Facebook fan page 'gast sein in gastein'.Become a fan
13.09.2017 - When the bounty of the fields is being brought in, Harvest Festival is celebrated throughout Salzburger Land with a wide variety of special events.Show article
21.03.2017 - 23.08.2016 – Being able to languish in the hot spring-fed thermal waters and wellness oases of Thermenhotels Gastein and feel the immediate soothing benefits, turns visitors into loyal guests. Beginning with 9th of June 2017, "Wellness Oasis" Gastein Valley will add yet another unique offer.Show article
Webcam pictures from the Gastein valley. Have a direct look with the webcams in the region. Best quality and different views available.Show live pictures
Discover the Spa Hotels Gastein - above all, the 4 star superior Hotel Norica, the 4 star Hotel Astoria and Alpina and the Tauernblick (3 Star living and 4 star enjoyment this is our motto) in beautiful Bad Hofgastein. Or enjoy the apartments in the Villa Frohsinn and Villa Angelika - the teams at the Spa Hotels Gastein are at your disposal.
Whether it is making the perfect choice for skiing in the winter or a relaxing hiking week in the summer. In any case, there is the Alpine Spa Gastein (32.000m2 of wellness oasis included for guests of the hotel Norica ), the healing cave and the Gastein Valley available - for a short break to relax or even 1 or 2 weeks - let yourself be seduced and inspire yourselves!
Unwind, relax and enjoy, in the Gastein Valley holiday dreams come true. Whether a treatment in the spa areas of the hotels, or even a whole day in the Alpine Spa Gastein, no wishes are left unfulfilled. Especially in the transitional seasons, spring and autumn, the Gastein Valley offers plenty for guests from all over the world. In the sunny hours a hike or a walk in the park of the Astoria Gardens - in case of bad weather in the spa. The programme is rounded off by the diverse cuisine at the hotel. A special at the Hotel Tauernblick is you pay for 3 Stars but enjoy the 4 star Hotel Alpina.
Proactive in the sauna, soothing in the radon galleries - everything is consolidated in Bad Hofgastein. In summer or winter, yoga and skiing - in Bad Hofgastein, the centre of the Gastein Valley, all the facilities and attractions are quick to reach predominately on foot, or even via indoor corridor from the Hotel Norica to the Alpine Spa. Purity in Gastein, you still experience unspoiled nature coupled with great comfort and infrastructure. Easily accessible, yet quiet.


text:
Naruto x UT
Type OVA
Airing Status Finished Airing
Duration 6 min. per episode
Air Date Jan 1, 2011
Season winter 2011
Producers Studio Pierrot

All-new animation offered throughout UNIQLO clothins stores in Japan on January 1, 2011. The DVD contains an exclusive version of Mayonaka Orchestra, by the Japanese rock band Aqua Timez. A limited number of the DVDs was offered as presents to people who bought UNIQLO's Naruto graphic T-shirts online or in their stores.

(Source: ANN, edited)

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Anime Relations
Parent story


text:
Human Service Intership (Southside)
Cause Areas
WhenIt's flexible! We'll work with your schedule.
Where485 Rodman AvenuePortsmouth, VA 23707
Bon Secours Hospice welcomes rising college seniors to apply for a semester internship with our organization. During your internship you will be provided with opportunities to interact with Hopsice patient's families on a regular basis. You will maintain a volunteer case load, attend staff meetings, Interdisciplinary group meetings, and be provided shadowing experiences with the clinical and administrative staff. If you are interested in working with seniors or in the human services field this will be a fantastic experience!
Good Match For
People 55+
Requirements & Commitment
- Background Check
- Must be at least 18
- Orientation or Training
- 2 to 4 Days a Week


text: I just bought a used PSP with the 6.60 pro b9 custom firmware installed. Everything was alright until a couple of days ago I turned it off accidentally, and when I wanted to boot again the cfw, it would just show the white psp screen and then it would turn off completely. I tried turning it on again and there were no problems, I just can't get the custom firmware to work again. Could you help me here, please?


text:
- Please select a date to see the proper prices!
Description of the accommodation:
Rooms, services Spend some remarkable days in Seattle and enjoy the hospitality of OAKWOOD SEATTLE SOUTH LK UNION Seattle! Guests looking for accommodation in Seattle are welcome to book a nicely furnished room at the hotel. The exact list of services available at OAKWOOD SEATTLE SOUTH LK UNION Seattle (including those for an extra fee) and the exact list of equipment in a room can be found on the information sheet below.
Payment Advance bank card payment or credit card guarantee may be required for the reservation, depending on the chosen date, room and price.
Arrival, opening hours The personnel of the hotel can speak in English with you.
OAKWOOD SEATTLE SOUTH LK UNION Seattle rooms Rooms
- Please select a date to see the proper prices!
Accommodation services
Pet friendly


text:
Starless night : The Legend of Drizzt Series, Book VIII. / R.A Salvatore.
Electronic resources
View other formats and editions
Record details
- ISBN: 9780786954087 (electronic bk)
- Physical Description: 1 online resource.
- Publisher: New York : Wizards of the Coast, 2009.
Content descriptions
|General Note:
| Title from eBook information screen..
|Summary, etc.:
| Return to the City of Spiders!Still reeling from the death of Wulfgar, Drizzt is allowed little time to grieve, for dark elves are massing in the caverns deep under Mithral Hall. To protect his adopted home, he'll have to return to the city of his birth, the evil City of Spiders. Menzoberranzan is one of the most dangerous places in the already perilous Underdark on a good day, but for Drizzt, a renegade with a price on his head, its certain death ever to set foot there again. But Drizzt Do'Urden and his companions have faced certain death before, and will gladly spend their lives for the sake of the dwarves of Mithral Hall.From the Paperback edition.
|System Details Note:
| Requires OverDrive Read (file size: N/A KB) or Adobe Digital Editions (file size: 3852 KB) or Amazon Kindle (file size: N/A KB).
Search for related items by subject
|Electronic books.


text:
500 Station Blvd. is a premier urban living community with stunning one, two and three-bedroom apartment homes. Every apartment home comes with lavish interiors, must-have architectural features, and a private balcony or a rooftop terrace. With endless amenities and a convenient location, everyone can find what they're looking for at 500 Station. Apply for our Aurora apartments today and dive into luxury.
More than just a place to live, 500 Station Blvd. treats you to the best amenities in town. The entire community is bursting with exciting activities and indulgent features. We have a massive onsite fitness center, a decadent resort-style swimming pool, and an outdoor grilling station lined with cozy fireplaces. Discover a world of possibilities and schedule a walkthrough of our Aurora, IL apartments today!
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Whether you're a corporate commuter, student, stager, or serving in the military, furniture rental is an ideal solution. From several months to several years and everything in between, CORT has the lease term options you need for your stay.
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Your prompt, professional delivery includes a complete furniture package setup down to the last pillow, lampshade, or spoon. CORT Furniture Rental provides a furnished life without compromise or commitment.
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Stock Graphic >> Pattern - Color Crush 2 {messy} 27189 by Joyful Heart Designs @ CreativeMarket
File Size: 36.13 MB; DPI: 300 DPI; Dimensions: 12 x 12 in.
Five grungy and messy papers, 12x12 inches, 300dpi, saved in digital .jpg format :)
My *updated* TOU.
These graphics are for personal use and limited commercial use.
What you CAN do with these.
- Scrap 4 Hire: creating scrapbooking layouts, albums, cards for pay.
- Blog and Site Design.
- Cards, calendars, various physical hybrid projects for sale.
What you CANNOT do with these.
- Create your own digital scrapbooking products for sale.
- Claim these graphics as your own.
If you have any questions email me: jenn.howland AT gmail.com
Keywords: digital, scrapbooking, paper, printable, textured, painted, altered, art, hybrid, background, grungy.


text:
Happy Fuzzy Friday!! This week the news was all abuzz with word of a very fuzzy fugitive, Rusty, a red panda who escaped from the Smithsonian's National Zoo in Washington, D.C. Rusty was last spotted on Sunday night at 6pm by the zookeepers and some time between then and 8am on Monday Rusty decided to go rogue. As red pandas are nocturnal, they spend most of their days sleeping in trees and have a tendency to stick close to their home, which in Rusty's case would be the red panda exhibit at the Smithsonian National Zoo. While zookeepers were indeed anxious about where Rusty could have disappeared to on Monday, they speculated he was probably napping in a tree nearby the zoo, however they did not rule out the possibility that someone may have taken him. Frantic, the zookeepers alerted the public and by noon EST alerts about the panda's disappearance were popping up everywhere, online in twitter feeds, on Facebook and in news reports coast to coast asking everyone in the DC area to be on the look out for runaway Rusty!
Well as they say, alls well that ends well, and thankfully in Rusty's case this is true as the rascally red panda was finally spotted in some bushes in the Adams-Morgan neighborhood later Monday afternoon. The person who spotted Rusty, snapped a picture of the renegade red panda and posted it on twitter, soon after zoo officials were on the scene to take Rusty back to his home at the zoo. Rusty had only been on exhibit at the Smithsonian's National Zoo for three weeks prior to his escape after arriving in April from Nebraska. The roly poly red panda will turn one year old next month. Take a look at some pictures of Rusty's great adventure down below!!
Continue Reading for MORE FUZZY!!


text:
This story appears in the April 5, 2010 issue of ESPN The Magazine.
"We're just 20 seconds away from the Final Four," Jay Wright remembers thinking as he glanced at the scoreboard at Boston's TD Banknorth Garden. "We're just 20 seconds away."
The Villanova Wildcats coach was sitting on a 75-72 lead over Big East rival Pittsburgh in the East Regional final of the 2009 NCAA Tournament.
Two months earlier, the Wildcats had beaten the Panthers by 10, in the last college game ever played at the Spectrum. Wright, a Pennsylvania native, admits feeling pressure to close the building with a W, as if he were standing at the free throw line with junior Reggie Redding as the guard iced the win.
"But now that night seems like a walk in the park," Wright says with a laugh. "Everything seems like a walk in the park after you've been through a final 20 seconds like we had in Boston."


text:
This delicate pattern with a mauve background would make a perfect addition to any room. Summer curtain fabric Mist is will be perfect attached to a roll down blind and surrounded by sheers to take a young woman into adulthood, yet versatile enough it could grace the windows of any other room in the house.
The delicate large floral print brings a sense of warmth to the room without overwhelming it. You can use the 100% cotton Summer curtain fabric Mist for other soft furnishing items as well as glamorous curtains. Because of stunning pattern and design of Summer curtain fabric Mist, it makes perfect cushion covers as well as a great medium for covering accent items such as small containers, throw pillows and waste-baskets.
You'll find that the Summer curtain fabric Mist is complementary to Oriental décor or fits beautifully into many other decorating themes, including rustic or country. Summer curtain fabric Mist is the perfect partner for other fabrics from our Prestigious Textiles of the same tone such as the stunning striped York Minster or the luxurious Geisha pattern continuing the floral theme but with branches, birds and birdcages. Mix the superb Prestigious Textiles fabrics for interesting focal points or as a cohesive material to complete a room.
This is the summer curtain fabric in the mist colourway.
Sample Information
We want you to find the perfect fabric for your home, so we offer free samples of all our curtain materials for you to gauge against the colour scheme in your home.
While we do our best to represent the true colour of the fabrics in our images, we understand that the pictures that you see may vary in colour from one computer to the next. Simply click on the sample button to receive a sample of the material and you can have a look at the fabric up close, for yourself!
Remember that our free samples only give a taster of the curtain material. We do our best to cut samples that show the full pattern of the cloth but it is not always possible to show the entire pattern for materials with larger designs. Each sample we send out is simply intended as a guide, to help you choose the fabric that best suits the interior of your home.
Care instructions
Hand Wash
Medium Iron
|Pattern Repeat (cm)
|100% Cotton
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"good service good quality"
"I choose this print to make roman blinds for my lounge. I have yet to make them but i love the fabric. "


text:
|Home | About | Journals | Submit | Contact Us | Français
The ENCODE project is an international consortium with a goal of cataloguing all the functional elements in the human genome. The ENCODE Data Coordination Center (DCC) at the University of California, Santa Cruz serves as the central repository for ENCODE data. In this role, the DCC offers a collection of high-throughput, genome-wide data generated with technologies such as ChIP-Seq, RNA-Seq, DNA digestion and others. This data helps illuminate transcription factor-binding sites, histone marks, chromatin accessibility, DNA methylation, RNA expression, RNA binding and other cell-state indicators. It includes sequences with quality scores, alignments, signals calculated from the alignments, and in most cases, element or peak calls calculated from the signal data. Each data set is available for visualization and download via the UCSC Genome Browser (http://genome.ucsc.edu/). ENCODE data can also be retrieved using a metadata system that captures the experimental parameters of each assay. The ENCODE web portal at UCSC (http://encodeproject.org/) provides information about the ENCODE data and links for access.
Since the Hershey–Chase experiments in the early 1950s (1), it has been known that DNA encodes heritable traits. These traits result from genes in DNA being transcribed into RNA, which might be spliced, transported to an appropriate cellular compartment, and translated into proteins. This process is regulated at many levels, including DNA methylation, chromatin modification, binding of transcription factors to the DNA, binding of splicing factors to the RNA and RNA transport. Arguably our heritable traits are determined as much through changes in regulation as differences in gene content (2).
The goal of the ENCODE project is to catalog the functional elements in the human genome that control these processes, through direct measurement using a variety of genomic technologies and detailed integrative analyses. ENCODE began with a pilot phase that focused on 1% of the genome (3), and scaled up to a genome-wide analysis in 2007.
The role of the ENCODE Data Coordination Center (DCC) is to organize and display the data generated by the labs in the consortium, and to ensure that the data meets specific quality standards when it is released to the public. Before a lab submits any data, the DCC and the lab draft a data agreement that defines the experimental parameters and associated metadata. The DCC validates incoming data to ensure consistency with the agreement. It then loads the data onto a test server for preliminary inspection, and coordinates with the labs to organize the data into a consistent set of tracks. When the tracks are ready, the DCC Quality Assurance team performs a series of integrity checks, verifies that the data is presented in a manner consistent with other browser data, and perhaps most importantly, verifies that the metadata and accompanying descriptive text are presented in a way that is useful to our users. The data is released on the public UCSC Genome Browser website only after all of these checks have been satisfied.
In parallel, data is analyzed by the ENCODE Data Analysis Center, a consortium of analysis teams from the various production labs plus other researchers. These teams develop standardized protocols to analyze data from novel assays, determine best practices, and produce a consistent set of analytical methods such as standardized peak callers and signal generation from alignment pile-ups.
The ENCODE labs are submitting a wide range of different experiment types to the DCC (Table 1).
In addition to primary experimental data sets, the ENCODE data also includes the Gencode V4 gene annotation set (4). This set contains both manually curated and annotated gene models, as well as automatically generated annotations for regions where manual annotation has not yet been performed, along with computationally identified pseudogenes.
Other data sets estimate the mapability of regions of the human genome for given sequencing read lengths. This mapability is determined by how many times a certain DNA sequence appears in the human genome, where higher numbers limit the ability to accurately map a sequence in that region.
For experimental data to be meaningful, the user must have some information on the context of the experiment. To communicate this contextual information, the DCC has established a controlled vocabulary of experimental metadata that includes such information as cell type and experiment type, as well as experiment-specific data such as the antibody used for transcription factor-binding experiments, insert length for paired-tag experiments and cellular compartment for organelle-specific measures of transcript presence. This metadata is presented in the Genome Browser track display, and is available in the download area of each ENCODE track.
Currently, most ENCODE tracks represent primary experimental data, as recorded by an experimental assay. As the ENCODE project matures, the DCC has begun publishing analysis tracks derived from processing the primary data. The first set of this data is displayed in Figure 1 as a rainbow multi-wiggle track. This composite track integrates six to eight different primary tracks representing RNA expression and histone modifications into a single display in which the signal from each track is rendered as a semi-transparent signal of a given color defined by the cell type assayed. This display facilitates the visual identification of constitutive and tissue-specific signals of cellular state.
Within each multi-cellular organism, the DNA in each cell is virtually identical, yet the regulatory signals from the configuration of this DNA yield a variety of cellular phenotypes depending on tissue type and developmental stage. To capture the breadth of these signals, the ENCODE project is surveying a variety of cellular contexts: over 100 different cell types have been designated for use. These are organized into three priority tiers: Tiers 1, 2 and 3. Table 2 lists the Tier 1 and 2 cell lines. All experiments are performed on the Tier 1 cell lines if possible. Most experiments are also performed on the Tier 2 cell lines; and selected (often lab-specific) experiments are performed on Tier 3 cell lines. This experimental design facilitates integrative analysis while capturing some breadth of cellular state.
Since late 2009 (5), the DCC has more than doubled the number of publicly available ENCODE tracks, to 863 as of August 2010. This includes 305 additional ChIP-Seq tracks that collectively now report on 98 sets of transcription factor-binding sites and 10 histone modifications. The DCC is hosting several new types of data this year, including Digital DNase Genomic Footprinting (6), ORChID predicted hydroxyl radical cleavage intensity on naked DNA (7), RIP-chip identification of RNA–protein-binding sites (8) and integrated regulatory tracks (see Figure 1). The RNA-Seq data sets have been augmented with longer reads, more paired reads and with data sets where the direction of transcription can be determined.
The human reference genome has transitioned from the hg18/NCBI36 assembly to hg19/GRCh37, and most tracks originally submitted on hg18 have been re-mapped to hg19. ENCODE data visualization has been enhanced through the deployment of new Genome Browser features, such as the ability to reorder tracks by dragging and dropping and support for BAM format (see the UCSC Genome Browser paper in this issue). The DCC ENCODE portal (http://genome.ucsc.edu/encode/) now provides additional features for interpreting ENCODE data, such as a listing of all registered metadata variables
We have added a set of sample Genome Browser sessions to the UCSC wiki (http://genomewiki.ucsc.edu/index.php/Encode_scenarios). These sessions illustrate how ENCODE data can be used in conjunction with other Genome Browser data to support biological inferences. Each image is a screenshot that links to a Genome Browser session (9) with a preconfigured set of tracks and display parameters. Within the session, a user can access all the standard Genome Browser functionality, such as moving to a nearby region or adding a custom track to the display.
Data produced by the labs affiliated with the ENCODE project is submitted to the DCC for display and data mining. Upon release, new ENCODE tracks are announced in the News section of the ENCODE DCC portal page and on the encode-announce mailing list (https://lists.soe.ucsc.edu/mailman/listinfo/encode-announce). ENCODE data is freely available to the public under the terms of the data release policy (http://genome.ucsc.edu/ENCODE/terms.html). Data publication is restricted for nine months following the initial submission to the DCC. During this time, interested researchers are encouraged to contact the data producers to explore potential collaborations. Following this period, the data may be used without restrictions. The Data Submission Status spreadsheet (Supplementary Data S1) contains the complete list of ENCODE experiments submitted to the DCC as of August 2010.
The ENCODE whole-genome data is interspersed among non-ENCODE data tracks on the Genome Browser. As of August 2010 this data was available primarily on the NCBI36/hg18 human assembly, but new data is being mapped to the GRCh37/hg19 assembly. Each type of data from each lab is organized into one composite track, which can contain multiple sub-tracks representing experimental conditions such as cell type and other assay specific attributes. If a track has many sub-tracks, then only selected sub-tracks will be displayed by default. The sub-track display can be configured via the track configuration pages. More information about browser use and ENCODE track configuration can be found in the Genome Browser user's guide: http://genome.ucsc.edu/goldenPath/help/hgTracksHelp.html.
All data submitted to the DCC is maintained in its original state on a file server accessible through FTP and HTTP. Downloadable files are arranged by submitting lab, with each lab/data-type combination in its own directory. Each submitted file can be associated with its metadata either visually by viewing the index file with a web browser or programmatically using the files.txt file present in each download directory. The download area is accessible via the Download links in the track details pages, or directly at http://genome.ucsc.edu/ENCODE/downloads.html. The ENCODE data is also being accessioned at NCBI GEO (http://www.ncbi.nlm.nih.gov/geo/info/ENCODE.html).
Most ENCODE data is represented in one of three different file types, all of which can be loaded as custom tracks: BAM (10) for alignment storage, bigWig (11) for signal graphs, and extended BED files containing peak data. The bigWig and BAM data formats are loss-less, randomly accessible, and indexed so that only the data needed for the current view is read from the file, which can be local or accessed over the internet (http://genome.ucsc.edu/FAQ/FAQformat).
For users investigating the worm (Caenorhabditis elegans) and fruitfly (Drosophila melanogaster) model organisms, we highly recommend the data from the modENCODE project (http://www.modencode.org/) (12). To explore further data on human genomic variation, we recommend the 1000 Genomes Project (http://www.1000genomes.org/) (13).
To provide additional information and training on using the Genome Browser, including access and use of ENCODE data, the DCC has contracted with OpenHelix (http://www.openhelix.com/). They offer training sessions on-site and at several highly attended worldwide meetings throughout the year, as well as online tutorials and reference materials.
In 2011, the ENCODE DCC plans to enhance both the accessibility and availability of new data. A new interface for the ENCODE portal will allow users to select tracks based on metadata, simplifying the task of determining which tracks may be relevant to their inquiries. To facilitate data browsing, UCSC is developing a track search tool that will streamline the process of locating specific data sets through the use of both free text search as well as a guided search through specific terms provided by the contributing labs to describe experiments. Microarray and sequence data generated by ENCODE will be submitted directly to the GEO and the Short Read Archive.
Over the next year, the DCC expects to provide several new forms of data, in addition to expanding the existing data sets to include new transcription factors and cell types. The new forms of data fall into three categories: analysis tracks, experimental validation and new ENCODE projects funded in 2009 through the American Recovery and Reinvestment Act (ARRA).
The ARRA-funded ENCODE projects will generate data on proteogenomics, ChIP-Seq experiments with epitope-tagged antibodies, and data derived from the mouse genome. The proteogenomics data contains peptides identified through mass spectrometry and mapped onto the genome with an HMM-based analysis (14). This extends RNA expression data by providing information on not only what is transcribed but also what is translated. Epitope tagging offers an alternative approach for generating antibodies, which can be a major challenge in ChIP-Seq experimentation. This approach offers the possibility of ChIP analysis of proteins that are recalcitrant to ChIP-grade antibody production, thus allowing the probing of a wider range of DNA-binding factors.
In 2009, the Mouse ENCODE project was created as an adjunct to ENCODE, with the goal of further understanding the human genome through a comparative analysis of mouse using analogous cell types and assays. The rule of thumb in comparative genomics is that genomic conservation suggests functional significance. Prior work suggests this to be true in RNA expression (15): RNA isoforms that occur consistently in related species largely seem more functional than species-specific RNA isoforms. However, the situation is more complex in regulatory regions, where overall conservation tends to be weaker. General associations between transcription factors and target genes can be strongly conserved, even when specific binding-site utilization is not (16). Therefore, identifying the molecular events that are conserved in human and mouse demands a careful analysis that includes measuring analogous cell types in both species. As much as possible, mouse experiments have been planned as analogs to human ENCODE experiments, to maximize the value of cross-species analysis. This experimental design focuses on three analogs to the human Tier 1 cell lines: MEL (analog of K562), CH12 (analog of GM12878) and CJ7 (analog of H1hESC). Experiments on many other mouse cell types are also planned. Many of these experiments take advantage of experimental systems that are not feasible in human, such as genetic knockouts and experiments on embryonic tissue.
Questions and feedback about the ENCODE data at UCSC should be directed to our ENCODE mailing list: ude.cscu.eos@edocne. General questions about the Genome Browser should be sent to the mailing lists described in the Genome Browser companion paper in this issue. We announce releases of new ENCODE data via the ENCODE announcement list, ude.cscu.eos@ecnuonna-edocne; to subscribe, visit https://lists.soe.ucsc.edu/mailman/listinfo/encode-announce.
Supplementary Data are available at NAR Online.
The National Human Genome Research Institute (grant 5P41HG002371-09 to the UCSC Center for Genomic Science); (grant 5U41HG004568-02 to the UCSC ENCODE Data Coordination Center); Howard Hughes Medical Institute [(HHMI) to D.H.]. Funding for open access charge: HHMI (to D.H.).
Conflict of interest statement. All the authors except M.S.C., C.A.S., V.S.M., B.B.S. and V.K., receive royalties from the sale of UCSC Genome Browser source code licenses to commercial entities.
The authors would like to thank the staff of the Center for Biomolecular Science and Engineering, our system administrators, Jorge Garcia, Erich Weiler, Victoria Lin and Alex Wolfe, as well as all the members of the labs in the ENCODE consortium.
PubMed Central Canada is a service of the Canadian Institutes of Health Research (CIHR) working in partnership with the National Research Council's national science library in cooperation with the National Center for Biotechnology Information at the U.S. National Library of Medicine(NCBI/NLM). It includes content provided to the PubMed Central International archive by participating publishers.


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The Time Has Come
The jury is in… and the age of antibiotic resistance is officially upon us.
No one can know exactly how things will develop in the days and months ahead… How long will it take for the problem to hit home? And how long it will take for medical systems around the world to respond?
We just don't know.
What We Do Know About Antimicrobial Resistance
Some people have done a lot of expensive research so that they could make an educated guess about what will happen. And the information they came back with is not encouraging.
Like the statement from World Health Organization Director-General Dr. Margaret Chan, where she claims that we are heading toward a post-antibiotic era in which common infections will once again kill.
Or the AMR study commissioned by the Prime Minister of the United Kingdom – which predicts that by 2050 we'll see over 10 million deaths annually from drug-resistant infections.
Take the Quiz: What is Your Antibiotics IQ?
What Can You Actually Do About Drug-Resistant Infections
The news is alarming. But being alarmed does nothing to improve your situation. Even if you've been keeping track of the news and following the latest developments – the news never tells you what you can actually do about it.
That's why we teamed up with Master Herbalist Doug Simons to produce this new training video called Treating Infections without Antibiotics. It's all about empowering you to care for common injuries and infections without the help of antibiotics.
Here is a short trailer for the video:
LIVE Training Webinar with Marjory Wildcraft and Doug Simons
The Treating Infections without Antibiotics DVD has already had such an overwhelming response from viewers that Doug has agreed to do a special, one-time-only live training webinar this Thursday for everyone who has purchased the video.
It doesn't matter if you purchased the physical DVD, or if you only bought the cheaper online streaming option. Everyone who has purchased the video before Midnight (Central Time) on July 6th, 2016 will be invited to take part in this special LIVE training webinar featuring Marjory Wildcraft and Master Herbalist Doug Simons.
During the webinar, Doug will share several real-life stories about injuries and infections he has treated, and the lessons he has learned through his practice. Everyone who attends will have the opportunity to ask Doug and Marjory questions – and they will both be available to answer your questions live, in real time.
Again, this special one-time live event is only available to those who purchase the video before Midnight (Central Time) this Wednesday, July 6th, 2016.
Click Here to Purchase Treating Infections without Antibiotics
The live webinar with Doug and Marjory will take place this Thursday, July 7th – don't miss out!
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Umbra Flo Chrome 6 Photo Frame
The guys from Umbra have done it again. This time, they've released this stunning Umbra Flo Chrome 6 Photo Frame. Armed with a chrome finish, it looks really chic and elegant. If you're ever at a loss on what to give a stylish friend, then this photo frame would be perfect.
It comes with sleek lines that create a modern aesthetic. On the other hand, you can never go wrong with chrome. There are 6 frames that come with this so you better start choosing which pictures you want to showcase. Pick photos with vivid colours or with a theme. You can also pick out random ones, it's up to you.
Go ahead, enjoy this Umbra frame today!
Umbra Flo Chrome 6 Photo Frame Specifications
Material: Chromed Metal
Holds 6 Photographs
Photograph Dimensions: 10cm x 15cm (4 x 6")
Designer: Fiona Ara
Product information
- 1412
- Photo frames
- 028295226516
- Umbra
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This item is sold and dispatched directly by Red Candy.
|Delivery cost
|Mainland UK - standard delivery
|Mainland UK - next working day delivery (order before 12pm)
We offer a 14 day no-quibble money-back guarantee, so if you're not delighted with your purchase you can return it for a refund. Note that bespoke and made-to-order items are excluded.
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Blanck Mass at Rich Mix
The electronic rock solo project of one half of F*ck Buttons John Power, performing songs from his third album World Eater.
Venue Details & Map
Rich Mix
- Address
35 - 47 Bethnal Green RoadLondonE1 6LA
- Telephone:
- +44 (0)20 7613 7498
- Public transport:
- Shoreditch High Street Station - Exit the station, turn out on to Bethnal Green Road. Turn right and cross over the road. Rich Mix is located a short distance along the road.


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Spring is on its way, and for a lot of us, it can be an inspiring time to think about our eating habits and how we might try to improve them, or make them more eco-friendly. One option that has become trendy over the past few years is Community Supported Agriculture (CSA). This model of food production and acquisition involves joining an association of people who have financially pledged to support one or more local farms, with growers and consumers sharing the risks and benefits of the harvest each year. The spring harvest in April/May is usually the cut-off for joining a CSA, so now is the time to educate yourself and sign up with one if it's something you're interested in.
This article is just a short overview of the topic, but hopefully it will be a good starting point for you to begin learning about this fantastic method of supporting eco-friendly and organic farms that are local to you.
What exactly is involved in being part of a CSA?
Members of a CSA, in exchange for their financial contributions, receive weekly (or other regularly scheduled) shares of food from a farm/group of farms in their region. As a member, you're supporting local agriculture directly, instead of going through the middle-man of a retailer or market. Designated community spaces serve as pickup locations — these can be schools, parks, or friendly neighborhood cafés.
Being part of a CSA is a commitment, and you can't just join last minute to come and pick out your produce. You have to sign up for at least a year's commitment by a certain date. That way you're with the farmers regardless of what happens over the seasons, or how plentiful (or not) the harvest may be that year. Before joining one, you need to really consider whether the program is right for you. Making the leap to a whole new way of doing your grocery "shopping" involves a long list of both pros and cons to weigh.
Because you're financially tied to the farm or group of farms supported by your CSA, you may have less choice over what kinds of produce you get, and will definitely be eating what is seasonally available! Although some CSAs allow for flexibility in choice of food, you're still beholden to some extent to the types of food that the farm grows or sets aside for your shares. It's not a great system if you're a picky eater, but can be a lot of fun for more adventurous home cooks. While differing throughout the season, your weekly share will usually contain at least four different vegetable varieties, in a generous quantity.
Why you might consider joining a CSA
As an environmentally minded person, joining a CSA means you know exactly where your food is coming from, and how it's being produced. Most CSAs receive all their produce from one farm, and there are often options to buy additional shares of eggs, meat, fruit, or cheese, depending on what the farm focuses on. You get to support a local business, and have a window into what is involved in the typical growing season for a small, usually family-run farm business. It's a fantastic learning experience!
Many CSAs organize trips for members to visit their principle farm, where you may get the chance to meet the farm's staff and ask them about their work. In addition, your contribution means a lot to the farm's financial security — everything from weather conditions to pest outbreaks to slow days at the farmers market can make a small farm vulnerable and their financial stability a fragile thing. Paying for your food shares up front (or via regular installments, depending on what kind of payment plans are offered), ensures them sales throughout the season, and some amount of predictable income.
Thinking about living green, you can choose to support a local farm which follows environmentally friendly growing practices or which raises meat ethically, if you choose to go that route. It's one of the best ways of ensuring that your food is healthy and meets your "green" expectations. Buying local is also a great way to reduce the carbon emissions produced by transporting your food long distances. You know your food is always going to be fresh and in season!
So how can you get involved in a CSA?
The best place to start is by searching online for a local CSA. Thanks to the internet, it's easier than ever to find CSAs operating in your area, learn about them, and decide whether to throw your lot in with a local farmer. There are many state-wide directories of CSAs that you can search, and a wealth of information available about the experience of being part of one.
A CSA usually runs like a co-op, so there may be a required volunteer shift or two. This is a time commitment, but lowers the administrative cost of the CSA for everyone who is a part of it. You can also take the opportunity to get more involved, if you like organizing group activities or have suggestions for improvements to the pickup process, etc. If you want to get more active in a good food cause, this is a great opportunity, and you'll often also get to chat with your neighbors during pick-up times and make more bonds in your community.
It doesn't have to be expensive, either. In fact, often a CSA or similar food share program can be very cost effective for those shopping on a budget. Generally a single share of produce in a large city will cost around $300-$400 in total, and runs from May or June to the end of October. That's approximately $12-$18 per week. Unfortunately, depending on how your local CSAs run, they may require all the money up front to join, though many do now offer installment-based payment systems. Some CSAs may also offer sliding-scale prices for lower-income families. Overall, the experience is a worthwhile one to consider for this year.
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Jennie Lyon is a green lifestyle writer and the owner of Sweet Greens, the award-winning green lifestyle blog. She posts on simple, fun ways families can go green together – starting with her own. When she isn't blogging, you will find her paddleboarding, sailing, beach-combing, camping, or spending time with her amazing husband and 14-year old son.


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Wayne Horvath
Contact Information
|Office: Princeton
|Phone: +1 609 514 8243
|Send a Message
Wayne is a director in the Real Estate Services Group. He has experience in the valuation of real properties and portfolios at the national level and has appraised property in many U.S. states. He has provided valuation services for financial reporting, investment and purchase consultation, mortgage submission, tax appeal, eminent domain, fair rental analysis, donation and a variety of litigation support matters. He also performs advisory services including support for litigation, appraisal review, market research, appraisal and project management, and offer/option analysis.
Property types Wayne has appraised include multifamily residential properties including market rate and subsidized housing; retail property; office buildings including medical offices; industrial facilities including manufacturing, warehousing/distribution, and flex space; large land holdings including developments, individual lots, subdivisions, and agricultural land; institutional facilities; and high-value residential properties. Property interests he has valued include fee simple, leased fee and leasehold estates. He has provided opinions for the valuation of open market exchanges, forced liquidation, fair accounting and going concern.
Prior to joining American Appraisal in 2010, Wayne served as a real estate appraiser and analyst at an independent appraisal firm providing similar services throughout the state of New Jersey. Additionally, he has experience in real estate sales and leasing, working with small investment groups in the Princeton area. Wayne also worked at the Center for Urban Policy Research (CUPR) at Rutgers University. At CUPR, he provided support for a large-scale contract that included various projects associated with a county-wide capital improvement plan. His efforts included organizing, prioritizing and planning the possible timing and potential funding sources for the various projects. In addition, he was involved in research and writing for the Impact Assessment of the New Jersey State Plan.
Wayne graduated from Rutgers University with a B.A. in urban planning and public policy. He is a Member of the Appraisal Institute.


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GraphicRiver Parcel Box 9593846
Stock Vector \ Objects \ Man-made Objects
Vector \ Illustration \ Isolated \ Realistic \ Background \ Surprise \ Symbol
Stock Vector - Parcel Box 9593846 by andegro4ka @ GraphicRiver
Stock Vector \ Objects \ Man-made Objects
Parcel box isolated on white photo-realistic vector illustration
Zip file includes.
- eps10, editable vector, RGB
- jpg, high-resolution, RGB
- psd
Layered: No; Graphics Files Included: Photoshop PSD, JPG Image, Vector EPS; Minimum Adobe CS Version: CS.
Children Toys Box; Garden Tools Box; Nautical Objects Box; Sport Objects Box; School Supplies Box; Cosmetics Box; Musical Instruments Box.
Keywords: bow, box, brown, cube, delivery, gift, icon, illustration, isolated, knot, mail, package, packaging, packet, paper, parcel, photo-realistic, pile, post, postage, postal, rope, send, shipment, small, surprise, symbol, vector, white background, wrapped.