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Bench-to-bedside review: Microdialysis in intensive care medicine
- Stephan Klaus1Email author,
- Matthias Heringlake1 and
- Ludger Bahlmann1
© BioMed Central Ltd 2004
Published: 3 June 2004
Microdialysis is a technique used to measure the concentrations of various compounds in the extracellular fluid of an organ or in a body fluid. It is a form of metabolic monitoring that provides real-time, continuous information on pathophysiological processes in target organs. It was introduced in the early 1970s, mainly to measure concentrations of neurotransmitters in animal experiments and clinical settings. Using commercial equipment it is now possible to conduct analyses at the bedside by collecting interstitial fluid for measurement of carbohydrate and lipid metabolites. Important research has been reported in the field of neurosurgery in recent decades, but use of metabolic monitoring in critical care medicine is not yet routine. The present review provides an overview of findings from clinical studies using microdialysis in critical care medicine, focusing on possible indications for clinical biochemical monitoring. An important message from the review is that sequential and tissue-specific metabolic monitoring, in vivo, is now available.
There is not yet any clinically established method for following local biochemical parameters in organs when they are affected by hypoxia or ischemia, or are developing organ failure. In the experimental setting it is possible to follow metabolic parameters such as glucose, lactate, pyruvate and glycerol using microdialysis equipment [1, 2]. In the clinical setting, thus far microdialysis has mostly been used in studies of subcutaneous adipose tissue [3], muscle [4] and human brain [5–8].
In intensive care medicine, diagnostic and therapeutic decisions are frequently based on measuring blood concentrations of indicator substances, but it is well known that biochemical reactions take place in the tissues. It has therefore been suggested that measurement of tissue chemistry reveals more valuable data than does analysis of systemic parameters in the blood [9]. Furthermore, in the past, detection of tissue concentrations of a substance of interest was hindered by the requirement for tissue harvesting [10], but harvesting is not necessary with microdialysis.
This article reviews the technique of microdialysis and its development from 'bench to bedside' for use in clinical research, major surgical interventions and critical care. We also discuss whether biochemical tissue monitoring has the potential to surpass blood analysis and become the standard technique for certain clinical procedures. Because fundamental research in numerous studies and reviews of the value of biochemical monitoring in the field of neurosurgery have been published, here we focus on the use of microdialysis in general perioperative and intensive care treatment.
Clinical application of microdialysis was 'catalyzed' by the development of commercially available microdialysis catheters that may be used in humans [9]. Because of modern technical innovations, it is now possible to determine dialysate and tissue concentrations immediately at the bedside during intensive care treatment [15]. The first reported application of microdialysis in humans was a study of interstitial glucose, which was published in 1987 [16]. Since then, microdialysis has been investigated in various human tissues, for example in cancer research [9] and pharmaceutical studies [17, 18], and in clinical research [19]. However, particular interest is currently devoted to perioperative biochemical monitoring in the fields of vascular, gastrointestinal and heart surgery, and postoperative observation.
Clinical applications
Microdialysis in vascular surgery
Several studies dealing with tissue vulnerability during ischemia and reperfusion have been reported [20, 21]. Previous studies on the consequences of ischemia in skeletal muscle usually involved venous blood sampling or tissue biopsies, but microdialysis has the advantage that metabolite levels can be monitored directly in the interstitial fluid of the tissue, even when blood flow is restricted. Lundberg and coworkers [22] used microdialysis to grade the severity of peripheral vessel disease. Responses of interstitial muscle concentrations of lactate and the lactate–pyruvate ratio to blood flow reduction were variable, whereas glucose concentration subsequently fell. Using microdialysis, Metzsch and coworkers [23] investigated metabolic changes during open and endovascular aortic surgery, and found that stent procedures had a lesser impact on regional tissue metabolism over 24 hours than did open aortic procedures.
In the field of orthopedic surgery, Korth and coworkers [24] demonstrated that interstitial concentrations of glucose, lactate, and hypoxanthine – indicators of tissue ischemia – change more markedly after exsanguination of the extremity than after circulatory occlusion alone. The energy status in muscle tissue was immediately visible after induction of ischemia, when glucose levels decreased and the extracellular concentrations of lactate and hypoxanthine increased.
Monitoring in the neonatal intensive care unit
Microdialysis in the neonatal intensive care unit is a new approach to continuous monitoring of newborn patients who are at at risk from hypoglycemia (a commonly encountered problem in neonatal intensive care). The objective of the study conducted Baumeister and coworkers [27] was to evaluate subcutaneous microdialysis in long-term glucose monitoring in the neonatal intensive care unit. By using subcutaneous microdialysis, blood draws and painful stress resulting from diagnostic blood sampling in high-risk neonates were reduced. Subcutaneous microdialysis has been used continuously for up to 4 days in neonates during intensive care, and for 3 and 7 days in adult insulin-dependent diabetic patients [19]. In their clinical study, Baumeister and coworkers [27] continued metabolic monitoring for 4–16 days and found a close correlation (r ~ 0.97) between blood and interstitial glucose levels.
Monitoring the gastrointestinal tract in the intensive care unit
Ensuring adequacy of visceral circulation is of high priority in critical illness. However, no clinical instrument has yet been developed to continuously monitor biochemical and circulatory parameters in this compartment [28, 29]. Decrease in intestinal blood flow or derangement of visceral oxygen supply is well known to induce local and systemic inflammation. This could subsequently be responsible for multiple organ dysfunction and/or failure [30]. Many investigators have attempted measure adequacy of splanchnic circulation either by measuring splanchnic blood flow in global splanchnic blood flow or local tissue perfusion or by evaluating metabolism in one region of the gastrointestinal tissue [28].
However, Tenhunen and coworkers have forwarded a theory, supported by several studies conducted in various experimental and clinical settings [31–36], that changes in tissue perfusion and metabolism in response to different drug interventions vary. That research group is by far the most experienced with respect to experimental biochemical monitoring of the gastrointestinal tract in the critical care setting. They identified intestinal histamine release in a selective regional intestinal ischemia–reperfusion model, not during ischemia but only during the reperfusion phase [33].
Following short-term endotoxin challenge, Oldner and coworkers [37] observed early increases in microdialysate lactate and hypoxanthine in ileum, as opposed to systemically detectable changes. However, insertion of a microdialysis probe into the intestinal wall is not feasible for clinical application. Subsequently, intraluminal [34] and intraperitoneal [38] applications were evaluated in experimental ischemia and hypoxia. Using microdialysis, Ungerstedt and colleagues [39] investigated local and regional gastrointestinal ischemia caused by vascular occlusion. Also in the setting of gastrointestinal ischemia caused by vascular occlusion, Jansson and coworkers [40] were the first to apply intraperitoneal microdialysis in clinical pilot studies of patients undergoing abdominal surgery. Intraperitoneal microdialysis appears to represent a very promising clinical tool for continuous monitoring of metabolic status in visceral tissues. It is minimally invasive; for example, the probe may placed be left in situ after laparotomy.
Liver monitoring in the intensive care unit
Despite improvements in liver preservation and surgery, a signficant incidence of graft dysfunction following liver transplantation persists. Microdialysis offers the possibility to monitor the liver during and after transplantation. Nowak and coworkers, who are pioneers in this field, investigated this application both experimentally [41] and clinically [42]. In their studies they investigated ischemia–reperfusion injury and post-transplant vascular complications, with apparent impact on hepatic metabolism, using microdialysis. They characterized the course of normalization in biochemical markers during the 72-hour postoperative period following liver transplantation. Nowak and coworkers concluded that the procedure is easy to perform and safe for the patient. They stated that the detection of specific pathologic changes (e.g. arterial and portal vein thrombosis, early graft rejection) might be possible using microdialysis, and that this should be addressed in further studies.
Monitoring sepsis
Stjernstrom and coworkers [15] were the first to report on the use of microdialysis in sepsis; they described case reports of microdialysis monitoring in patients with septic shock. Clinically, Martinez and coworkers [45] evaluated adipose tissue metabolism in severely ill patients. The aim of the latter investigation was to study whole body substrate utilization and adipose tissue lactate and glycerol release in healthy human volunteers and in two groups of critically ill patients: one group of patients with severe sepsis or septic shock and another with circulatory failure after cardiac surgery. Differences in tissue metabolic response were found between sepsis/septic shock and cardiac failure patients using microdialysis. The observations summarized above, along with Fink's theory of 'cytopathic hypoxia' [46] in septic states, add weight to a recommendation to introduce biochemical tissue monitoring into critical care practice.
Monitoring pharmacological concentrations
Achievement of appropriate concentrations of antibiotics at target sites is associated with clinical outcome [47] and therefore is of particular importance. Recent data, however, strongly suggest that concentrations of antibiotics reached in the interstitium of soft tissues might be ineffective in critically ill patients, despite achievement of adequate plasma concentrations [18]. Fundamental experimental research in the field of drug monitoring using microdialysis has been reported [48]; this was recently reviewed by Joukhadar and coworkers [17].
Monitoring myocardial metabolism
Several experimental approaches such as biochemical analysis of coronary sinus blood, myocardial biopsy and magnetic resonance imaging have been taken in order to describe the metabolic changes that occur during and after cardiopulmonary bypass [49]. With the exception of septic conditions [46], the interstitial concentration of lactate has been shown to be closely related to variations in tissue perfusion [1] and may thus be used as a surrogate marker of myocardial ischemia. Following experimental evaluation by Kennergren and coworkers [49], Habicht and colleagues [50] were the first to introduce this concept into the clinic by inserting microdialysis probes into the interventricular septum of the human heart. Kennergren and colleagues [51] then focused on changes in troponin T and aspartate transferase in patients undergoing coronary artery bypass grafting and valve surgery.
We investigated the course of myocardial metabolism in patients undergoing standard coronary artery bypass grafting [52]. In contrast to blood levels, myocardial lactate–pyruvate ratio exhibited marked changes during the period of observation; pyruvate was found to be a promising indicator of tissue reperfusion. In a recent study of myocardial microdialysis (unpublished data), we categorized patients by lactate concentration at baseline into a high lactate group and a low lactate group. We found an association between increased myocardial lactate levels – as determined by microdialysis – and reduced myocardial performance with difficult weaning from cardiopulmonary bypass during coronary artery bypass grafting. This suggests that myocardial microdialysis may be a useful adjunct for stratifying treatment in these interventions (unpublished data). Microdialysis may reveal promising diagnostic and therapeutic options by permitting analysis of the effects of different treatment strategies on myocardial metabolism (i.e. the 'target tissue' of therapeutic interventions) in cardiac surgical patients.
Microdialysis has been introduced into several sectors of critical care medicine. The precise role and cost-effectiveness of microdialysis, in comparison with well established technologies, in developing strategies to improve the organ function in intensive care remain to be determined. However, even in the well established field of neurosurgery, the clinical use microdialysis has not yet been found to improve outcome. Current data support a recommendation to introduce this new technique to evaluate the adequacy of regional tissue metabolism; it may even permit monitoring of the effects of therapeutic interventions. Further studies of various approaches are needed to conclude which seems clinically most feasible, which is sufficiently non-invasive, and which supplies the clinician with the most physiologically relevant information. Whether clinicians will be able to monitor their 'tissues of interest' directly, with microdialysis playing a key role, will be determined by the results of further evaluation.
Authors' Affiliations
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Build Guide by RitsuX
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Vayne Build
Ability Sequence
Not Updated For Current Season
The masteries shown here are not yet updated for the current season, the guide author needs to set up the new masteries. As such, they will be different than the masteries you see in-game.
i bought vayne day one, and as most know she has damage out put but is very squishy. so i found when i buffed her early game survivability, and got fed that my late game squishyness didn't matter because they only way i was getting killed was from getting cced. so after having much success with this build i decided to share it with you guys.
If your just going read my build, and down vote it without trying it please leave because i dont care for your opinion, if your not going try it.
as well as if you just joined today and have like 2 posts, you opinions will not be taken into consideration, I ask you kindly to please gtfo.
Pros / Cons
- great damage output
- great chaser
- the ability to make players qq lol
- glass cannon(squishy)
- mobility is **** when running from enemies
- useless if cced
ok my standard normal game runes i run APR reds, Attack Speed yellows, CDR Blues, and APR Quins.
now for ever ****** that doesnt get that i added, Armor yellows, and magic resist blues, and health quins, that what i use for ranked, because in ranked you wont be facing noobs who dont know how to focus the squishy dps, you'll be facing people that want to win especially mid elo.
early game
so to start you want to grab a dorans sheild and head either top or bottom maybe even mid if your comfortable with your vayne skills, other wise mid can be tough(until you learn to last hit and harass at the same time.) and start with silver bolts(this gives you great harass because at low levels when people see one stack on them selves the usually run back, if not once the realize they have 2 stacks it will be to late and they either take the 20+4% of their max health or run back.
At level 2 you will become more dominant for the simple fact that now you have tumble, and you can now ensure that you will always proc silver bolts. this means that either that in order to farm they have to take damage or back off, if there stupid and don't back off they will become an easy kill(especially if you only last hitting creeps and keeping the wave out of turret range or mid lane, meaning they will be over extended,that compiled with your passive means they wont get away.) Continue this process and rake in the gold, and at evel 6 you should have 1.5k just farming minions and 1.8-2k with 2-4 champ kills(not the champ kills wont always be that high early game, my number is purely theoretical, based on what i have done, and seen players do.)
so at the end of early game going into mid game you should have boots and a B.f sword(big boost for your q)
as any good player knows last hitting minions is a must. I can't tell you how many times i see noobs play champs that are item dependent senselessly auto attacking creeps and trying to rely on kills to build, then qq about ks "i need to build dont ks." Vayne is an assassin and rely's on kills, but having a great farm helps so much especially if you're having a ****py early game.
the enemy team will be wondering "how you got fed" and start qquing uncontrollably
mid game
since vayne is an assassin at level 6 you want start ganking, this is a big part of what playing an assassin champ means. Always make sure you tell the lane when you're coming, I've seen so many ganks fail, because vayne's will come into lane unannounced, but most of you are gona say "learn to map awareness noob" but most people don't do it. so with that being said always pay like your team is ******ed especially in solo que ranked and unranked.
Keep ganking, and farming till you get enough to finish Black cleaver and ionian boots of lucidity, this allows you to attack often( quicker w procs) and be able to spam tumble more. at this point if your not getting focused, and cced you should be getting fed because no one is going to be able run.
by level 12 you should have black cleaver,dorans sheild, ionian boots,sheen and if your really fed maybe even phage going into late game also known as team fight stage.
ganking/tower diving
although vayne is squishy, she is still a great tower diver. with ghost flash and her ult it will be cake walk.
so when chasing ans tower dive only do it with ghost ult and flash up so you can get in kill and get out with out dying( never dive 2v1 or vs a champ that can stun slow or fear) below i will name champs that you can easily dive against.
Champions to dive against
- akali
- Annie(if stun is not up)
- evelyn(make sure to keep attacking so she cant stealth)
- gangplank(id he used he his ult already)
- himerdinger(just tumble away from concision grandades)
- janna
- master yi
- miss fortune
- sivir
- sona(if ult is not up)
- sorakka
- vayne(be careful not not to get pined to the wall)
- warwick(if suppresion is on cd and he low on mana because other wise he cn just kep quing as you chase giving tower time to kill you.)
late game
at this point vayne's build is pretty op and can do awesome damage but we're gona keep farming as much as possible before team fights break out so we can get our madred's blood razor, and finish trinity's with those two items there will be no one who can stop you.
and remember since you are squishy wait for the tank to start the fight and stay at the back of the group since you are ranged, and make sure to tumble from side to side so that you don't tumble into range of melee and their tank.
alright now its time to team fight, i cant stress how important it is to not start the fight, you are not the tank!
with that being said, the best way to start a fight is to be hiding in the bush and let them think its a 4v5 and that they can win, usually when they see the 4v5 the'll commit, start bu ulting and tumbling in(for stealth) open up on their squishiest champs leaving tankier champs for later.
so all in all vayne is a great champ even after her nerf, and in all honesty i was waiting for it because i wana show that shes a great champ nerfed or not, and that if you cant kill her you just suck at countering and probably think all champs are unbalanced.
**on a side not if someone can pm me and show me how to do item , spell icons,and mastery icons so i can do an in depth itemization guide and spell rotation guide, that would be awesome. because i would like to finish up this guide.

subset: commoncrawl


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Should state and local governments have the right to tax the Internet, a global communications medium? This topic has been the subject of hot debate in Congress. In early 1997, Representative Christopher Cox (R-CA) and Senator Ron Wyden (D-OR) introduced the Internet Tax Freedom Act (H.R. 1054/S. 442), under which there would be a six-year moratorium on state or local Internet taxes in order to facilitate further study of the feasibility of taxing commerce over the Internet. Both bills were approved in committee last fall and have continued to attract bipartisan support. Policies like those embodied in the Internet Tax Freedom Act would keep this vibrant global medium free of unnecessary taxes that could strangle its technological evolution. An intensive lobbying effort by state and local interest groups, however, recently forced Representative Cox and others in Congress to consider a compromise that could open the floodgates of state and local taxation. Congress would be wise to reject the compromise and push forward with its original plan to keep the heavy hand of government off Internet commerce.
Problems with the Pro-Tax Compromise
The proposed Internet Tax Freedom Act has drawn vociferous opposition from state and local policy makers who oppose any limits on their efforts to reap revenue from this technology for state treasuries. During the first three months of 1998, an intensive lobbying effort was waged by such state and local groups as the National Governors' Association, National Conference of State Legislators, Council of State Governments, National Association of Counties, National League of Cities, and U.S. Conference of Mayors. Their purpose: To convince the media, the public, and congressional leaders that the Internet Tax Freedom Act is an unjustifiable federal preemption of state and local taxing authority.
Although state and local governments enjoy a significant amount of freedom in determining their tax policies, their taxing discretion does not extend beyond their geographic boundaries. Policymakers and businesses opposed to Internet taxes argue that the Internet should remain a "global free trade zone," unencumbered by overlapping and discriminatory taxes imposed by the country's more than 30,000 taxing jurisdictions. Multiple layers of taxation inevitably would hinder the continued growth of this technology.
The U.S. Constitution is clear: Congress has sole jurisdiction over matters relating to interstate commerce. Both the Internet and Internet-based transactions fall squarely within the ambit of interstate commerce. It is difficult to think of another industry or technology in modern history with a more interstate (indeed, global) scope than the Internet. It is difficult to imagine how fast-paced, intangible electronic transactions could be taxed efficiently by 30,000 jurisdictions, to say nothing of the reasons that some federal legislators would cave in to the untenable and unconstitutional demands put forth by state and local officials.
On March 19, 1998, Representative Cox announced a compromise with state and local officials that would (1) decrease the length of the moratorium from six to three years; (2) grandfather in existing state and local Internet taxes; and (3) establish an open-ended Commission on Internet Commerce, which would be required to submit to the President a system for state-based Internet taxation within two years of enactment. The President then would submit a report to Congress that recommends either approving or disapproving the commission's proposals.
The establishment of such a commission presents several problems:
First, representatives from the state and local groups that lobbied for the right to impose new taxes on the Internet (including the interest groups listed above) would constitute a majority of the 29-member commission. With such majority representation, any decisions that were made regarding future tax policy most likely would be geared toward the general expansion of Internet taxes.
Second, although the compromise sensibly would require the Commission on Internet Commerce to ban specific types of Internet taxes (such as access taxes, bit taxes, or bandwidth taxes), it would nullify this policy's effect partially by encouraging the commission to establish the equivalent of a national sales tax on Internet transactions. The commission would construct guidelines allowing states to impose Internet sales or use taxes so long as they do so in a uniform, simplified manner. Not only is it unlikely that these taxes would be imposed in a uniform, simplified manner, the reason remains unclear for the states to be given the power to collect taxes extraterritorially.
Third, the Commission on Internet Commerce would be encouraged to use an independent, third-party system for the administration and collection of sales and use taxes. Although this may sound reasonable, in practice the third-party agency could evolve into a large agency with an incentive to collect more and more taxes to generate higher profits. History is replete with examples of such third-party tax collection systems that violated taxpayers' rights and privacy. Such a system imposed on the Internet would destroy much of the Internet's vitality and ingenuity and discourage the continued growth of electronic commerce.
Fourth, an appointed commission would not be accountable to the electorate. Congress should not delegate any of its responsibilities or authority to such a group; it should make such decisions on its own, using explicit statutory language. Although no proposals would take effect until Congress and the President had signed them into law, those who backed creating such a commission must be ready for unintended consequences. For example, once it proposed an Internet tax system, the commission would lobby Congress to support it. Congress would be hard-pressed to withstand the political pressure from the powerful state and local interest groups represented on the commission.
No Time to Back Down
In reality, the so-called compromise bill represents a substantial sellout to state and local officials who are seeking tax revenue for their own treasuries. Once the shortened moratorium had expired, the Commission on Internet Commerce would pressure federal policy makers to implement the wishes of these special interests, making the Internet the latest victim of what Representative Cox once called America's "tax vultures."
It still is possible for Congress to avoid adopting this shortsighted compromise, which received only a tepid response in the Senate. Senator Wyden and the chairman of the Senate Commerce Committee, John McCain (R-AZ), have expressed their dissatisfaction with elements of the deal. Other Members should hold fast to the original plan to keep the Internet free of burdensome and discriminatory taxes. Congress should send a clear message to the state and local governments that want to tax--unconstitutionally--this exciting new global medium: No new Internet taxes.
--Adam D. Thierer is Alex C. Walker Fellow in Economic Policy at The Heritage Foundation.


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ARLINGTON, Texas -- Texas Rangers second baseman Ian Kinsler has received a one-game suspension and an undisclosed fine by Major League Baseball for returning to the field to celebrate Nelson Cruz's walk-off home run after he had been ejected Friday.
Kinsler is appealing the suspension and was able to play in Tuesday night's game against the Detroit Tigers.
"I think it's a little too harsh," Kinsler said. "It's a little unreasonable. There's not really too much common sense in [the rule], but they have rules for a reason."
Umpire Dale Scott tossed Kinsler after the second baseman had argued balls and strikes in the bottom of the 10th inning. Players are supposed to leave the field and not return after they are ejected. But after Cruz hit his home run in the 13th to give the Rangers the win over the Yankees on Friday, Kinsler returned to celebrate with his teammates on the field as Cruz rounded the bases.
Richard Durrett covers the Rangers for ESPNDallas.com. You can follow him on Twitter or leave a question for his weekly mailbag.


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Cheddar-Bacon Biscuits
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Prep Time: 10 minutes
Cook Time: 30 minutes
Servings: 3
What are the secrets to making tender, flaky biscuits? When cutting the butter into the flour, work quickly so it doesn't melt too much before you put the biscuits in the oven. And when adding the milk, don't overmix the dough; stir until the ingredients are just combined.
- 97
- 3 cups all-purpose flour
- 4 tsp. baking powder
- 3/4 tsp. salt
- 8 Tbs. (1 stick) cold unsalted butter
- 1 cup finely shredded cheddar cheese
- 1/3 cup chopped fresh chives
- 6 bacon slices, finely chopped and fried
until crisp
- 1 1/2 cups milk
Wine PairingThis pairs well with smooth, full-bodied red wines like the Bodegas Gancedo Ucedo Mencia, Bierzo from our Wine Club.
Directions:Position a rack in the lower third of an oven and preheat to 400ºF. Lightly spray a biscuit pan with nonstick cooking spray.
In a large bowl, sift together the flour, baking powder and salt. Using a pastry blender or 2 knives, cut in the butter until it resembles coarse meal. Add the cheese, chives and bacon; using a fork, stir until evenly distributed. Add the milk; using a rubber spatula, stir until just combined. Divide the dough among the wells of the prepared pan.
Bake until the biscuits are golden and a toothpick inserted into the center of a biscuit comes out clean, about 30 minutes. Transfer the pan to a wire rack and let cool for 15 minutes. Invert the pan onto the rack and lift off the pan. Let cool for 5 minutes before serving.
Williams-Sonoma Kitchen.


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Quick Details
- Place of Origin: Sichuan, China (Mainland)
- Brand Name: Lisaurus
- Model Number: Lisaurus-L501
- Type: animal skeleton replica
- Title: animal skeleton replica
- Technics: All handmade and assemblage
- Color: Lifelike color or customized
- Usage: Museum park,Theme park ,dinosaur exhibitions
- After service: 12 months & lifelong technology and repair support.
- Advantage: Waterproof.Freezeproof.dampproof
- Certifcate: CE&Rohs issued by DEKRA Germany
- Material: High quality fiberglass,High density sponge
- Is_Customized: Yes
- Website: www.lisaurus.com
Packaging & Delivery
|Packaging Details
|animal skeleton replica:Wooden cases/ air case or customized .
|Delivery Time
|28days or Depend on the quantity of order
Lisaurus- Artificial Small dinosaur skeleton replica for sale
1.Life Size Simulation Dinosaur Fossil;
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3.CE&Rohs materials .
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Steel ,fiberglass, rubber, resin.
(life size or as customer request).It can be made into different size,
custom as per buyer's choice.
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Delivery time
28days or depend on our order.
Packing details
Air case/ wooden case . The dinosaur skeleton should be cut into some parts and then install by customers.
Assemblage,Waterproof, High imitation fossils, museum quality.
Warranty period
/After service
12 months after the completion of installation except artificial
damage.(this product could preserve for a long time).
Payment terms
T/T,L/C,western union,Escrow etc.
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outdoor playgrounds/exhibition, shopping malls and so on.
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by sea or air/Railway is both ok for us , we will control the safety of the goods.
Clients: How about the warranty period of these products?
Lisuarus : All of our products have one year warranty period and a life long technical support.
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|Ciego de Avila Province is in the central part of Cuba. It is probably most famous for its friendly people in the city of Moron, the bass fishing at Lake Redonda, the hunting around Moron, the bonefish, tarpon, permit and scuba diving at the Last Paradise Keys and more recently the founding and development of Cayo Coco!
For the traveler not interested in the famous Cuban places like Havana, Santiago de Cuba and Varadero Beach, a great selection is the Province of Ciego de Avila. It has lots to offer!
For example, the city of Moron (about 50,000 people) is fast becoming known as Cuba's friendliest city. In some opinions, this indeed is the real Cuba with the real Cuban people.
Ernest Hemingway loved this area of Cuba and spent a lot of time at Cayo Guillermo, a place where the hotels, the bars and even the restaurants are all named after him, his home, his fishing guide, etc.
Ciego de Avila is also the home of Fello Echemandia, known by many as the world's greatest trophy bass fisherman. Fello is 45 times Cuban National Fishing Champion. He has to his record a 21 pound bass, a 20.16 pound bass, too many over 15 pounds to mention and an unbelievable of bass over 10 pounds. A legend indeed! Some of the 13 million American bass fishermen might be interested in visiting the apartment of Fello, get your picture made with him, get an autograph and let him tell you some of the funniest and most incredible fishing stories imaginable. Fello has fished with many of the great American fishermen like Roland Martin, Jimmy Houston and Jerry Rhyne. A $10 tip might be in order.
Another local legend is Tomas Marino, the man most Americans know as the man most responsible for the incredible duck, dove, quail and white crowned pigeon hunting that has helped to make the city of Moron famous. Tomas is now at retirement age and you also might want to visit his home and let him tell you about some of the world's greatest hunters and stories about hunting and life in Cuba. The man wears a perpetual smile, maybe the friendliest of all Cubans. Get your picture made with him, an autograph and a delightful human experience. Likewise a $10 tip might be in order.
Another local legend was Rafael Cabrerra , a man who recently passed away, but who was known by many experts as the best bone fisherman in the entire Caribbean. Rafael, thanks for the memories!
Ciego de Avila Province is rapidly becoming one of the best opportunities for foreign investment capital. If you don't believe it, just check with the Italians, Germans and Canadians who are already working and investing in the Province.
Cuba's top investment experts live in this area like Francisco Herrera and his son Yuri, Raul Naranjo, Tito Jemenez, Oscarito Munos, Casamiro Fernandez (boss of Cubatur) and Tania Toledo Perez. We can arrange for you to meet these people or you can invite them to meet you in Mexico, Canada or Nassau! Delightful people....all of them!
The City of Moron has two nice places to stay and some very good private homes. The Moron Hotel is a 144 room hotel, newly remodeled, with air conditioning, satellite TV, swimming pool and a red hot disco. The Club Casa y Pesca is a beautiful two story facility with only seven rooms. The pool is nice and the food is excellent. If all are full, ask around for one of great private homes with rental rooms. You won't be disappointed!
Ciego de Avila City is the capital of the Province. It has about 85,000 citizens and one can find plenty to see and do here. The best hotels are the Hotel Ciego de Avila, a 144 room hotel (photo above); Hotel Santiago-Habana, a hotel with 76 rooms and the Motel Las Canas, about 5 miles west of the center of town with 74 rooms in prefabricatd cabins. The price is right.
A very interesting place is the village of Jucaro, a fishing village on the south coast near the Bay of Anna Maria. This is the real Cuba.
A rather new international airport, Maximo Gomez Airport, located about half way between Ciego de Avila City and the City of Moron. Flights can be arranged from Nassau or Cancun that connect with flights to Ciego de Avila Province helping to avoid having to overnight in Havana.
Of course, the top two attractions are no doubt Cayo Coco and Cayo Guillermo. Several luxury hotels are set on some of the most beautiful beaches Cuba has to offer.
Cayo Guillermo offers two hotels named after Hemingways home and one of his other famous fishing spots, Villa Vigia and Villa Cojimar.
|If you are interested in making a reservation...just click on our e-mail address below or call us in at at 760-487-5212. As the Americans who have led the fight to open up travel to Cuba and who helped to make Cuba the outstanding travel destination that is is today, we would appreciate your business! Thanks.
For more information or reservations:
Email: email@example.com


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Global Account Manager - Japan (CGEM AGES Inbound Sales)
Location:Tokyo, Kanto, Japan
Area of InterestSales - Services, Solutions, Customer Success
Job TypeProfessional
Technology Interest*None
Job Id1210403
What You'll Do
The Global Account Manager acts as the sales leader of a/or multiple Global Accounts and is responsible for overall business relationships across a significant country or across the APAC region.
Job Responsibilities
Global Account Leadership
- Global, Region and Country Leadership of the account(s) by leading a virtual team across the region.
Build Trusted Client Relationships
- Build a strong and trusted advisor relationship with the customer at CXO level including the lines of business
Account Strategy and Goals
- Work with HQ team to develop an integrated account plan. Lead the functional team (service sales and delivery, architectural team, Capital, Channel) to position entire portfolio including hardware, software and service to drive the adoption in the region
Focus on Strategic Deals
- Identify and close regional / country strategic opportunities in the accounts through strong relationships with key stakeholders and regional executive decision makers to maximize Cisco opportunity
Innovation at the edge
- Work with the customer to develop an innovation strategy to help save cost and deliver value to their business in the local regulatory and competitive environment
Operational Excellence across the Region
- Drive the discipline of the sales team for weekly, monthly and quarterly sales forecast. Orchestrate Cisco service delivery resource to maintain high level of customer satisfaction
Who You'll Work With
Reporting directly to Regional Manager of Global Enterprise Segment in APAC, the GAM works with HQ, regional and country teams to create a seamless customer experience, position Cisco technologies, services and flexible consumption models that deliver business outcomes. The GAM manages a set of global accounts in the region and is measured against the quota attainment and customer satisfaction.
Who You Are
- 8+ years sales management experience in an ICT Company.
- Fluent in English and Japanese.
- Track record of selling large and complex technology solutions with specific focus on driving business outcomes for clients and services-led strategy
- Self-starter with the ability to build executive relationships, articulate product and business strategies, create demand and close deals
- Ability to lead a virtual team from the various lines of business within Cisco Systems including Inside Sales, Consultant Systems Engineering, Consulting, Marketing, Product Management and Business Unit
- Strong leadership skills in a global teaming environment
- Specific examples of closing large, strategic deals
- CXO experience and executive presence
Why Cisco
We connect everything: people, processes, data, and things. We innovate everywhere, taking bold risks to shape the technologies that give us smart cities, connected cars, and handheld hospitals. And we do it in style with unique personalities who aren't afraid to change the way the world works, lives, plays and learns.
We are thought leaders, tech geeks, pop culture aficionados, and we even have a few purple haired rock stars. We celebrate the creativity and diversity that fuels our innovation. We are dreamers and we are doers.
We Are Cisco.
We connect everything - people, process, data and things. We innovate everywhere to create fresh ideas and possibilities. We make a meaningful difference that will benefit everyone - our people, our customers and the world around us.
Our technology changes the way the world works, lives, plays and learns. But our edge doesn't come from technology. It comes from our people. We're looking for the kind of people who take smart risks, thrive in diverse environments, inspire their colleagues, and are committed to having an impact on the world. Whether you create technology solutions that redefine business or build connections that strengthen the community, you can make it happen at Cisco!


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Henry Cejudo arrived in the UFC with a ton of buzz behind him, that tends to happen with Olympic gold medalists, but has he earned a title shot? Demetrious Johnson doesn't seem to think so…
Following Cejudo's split decision win over Jussier "Formiga" last November, the decorated wrestler has been booked to fight the flyweight champ Johnson, on April 23rd. The scrap will co-headline UFC 197.
The win over "Formiga" was Cejudo's fourth straight with the UFC, and followed victories over Dustin Kimura, Chris Cariaso and Chico Camus.
Recently Johnson was in attendance at EA Sports' UFC 2 launch, and while discussing Cejudo's title shot, the champ stated (quote via MMA Fighting.com):
"There's guys out there who have fought way tougher competition and have finishes and knockouts on their résumé," Johnson said. "But since he's a gold medalist in Olympic wrestling, he's undefeated … the man is about to fight for a world title and it's his fourth fight in the UFC. That's how the business runs."
"…The man has 10 fights in his total career," Johnson added later in the story. "That shows you how fast you can jump and get to the pinnacle of this sport real, real fast. I've been here for a long, long time."
How about that huh? Is it just me? Or has Johnson really started to open up with the comments in recent months?
Now, even the biggest Cejudo booster would have to agree with some of what Johnson has said here. Of the current top 15, 125 rankings, the only contender Cejudo has defeated is "Formiga". But, the reality is that because Johnson is so ridiculously good, he's defeated four of the top five contenders already. In the case of Joseph Benavidez and John Dodson, he's handed them losses twice each.
So, going with Cejudo makes sense, and as Johnson alluded to, it's good business as well.
UFC 197 will be hosted by the MGM Grand Garden Arena in Las Vegas, and will feature Daniel Cormier – Jon Jones II.


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Podcasts: Black Gospel Music
Podcast (audio library):
Podcast are ongoing collection audio interviews and speeches of and by black elders, professionals, young people and others who are invested in our community. It was conceived in 2005 as learning tool for and of black people.
The function of the podcast is to:
- Use audios "Theater of the Mind" to convey blackness on our website.
- Serve as a voice for our views, advice, affirmations and truths.
- Enhance existing text articles in our website.
- Support the oral traditions that are the trademark of black people.
- Spotlight un-stereotypical interpretations of who we are.
Subscribe to the podcast:
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Results of New Wine Consumer Survey
(Caveat: I tend to distrust all wine consumer research as wine consumers are notorious for overstating their preferred price-point as well as their own knowledge base - the "wanna-be wine snob phenomenon")
American wine drinkers are more likely than the rest of the US population to:
- Be open to new experiences
- Follow their own path in life
- Be information-savvy and confident consumers
- Desire intangibles, experiences and emotions
- Have their life priorities in order
- Eschew brands as badges
California wines also came across as best positioned to take advantage of these trends as they rank first in familiarity, consumption and positive impressions - as compared to other wine-producing regions.
Its also interesting to note the rankings of what attributes are important to U.S. wine consumers:
Color and Varietal 69%
Consistent taste bottle to bottle 64%
Value 62%
Familiarity/Comfort with 56%
Food pairing 54%
Good for everyday 48%
Special treat 43%
Personal recommendation 39%
Name/label 37%
Country/region 36%
Reputation 32%
Stunningly, the appellation/origin of the wine is only important to 36% of buyers, but varietal is important to 69%. You have to ask why, then, are most stores laid out by region, not by varietal? Let's put the Chilean Chardonnay next to the White Burgundy, no?
In another chart, Yankelovich showed that California was the only region to have both high familiarity and high frequency of purchase with these consumers. Italy and France showed the highest Frequency of other non-California regions, but not the familiarity of California (probably due to the difficulty of understanding their appellation and labelling systems). Following France and Italy were mostly "new world" regions - Australia, Spain, New York, Washington, Oregon, Chile, New Zealand, Argentina and South Africa, in that order.


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RepairPal is your advocate for car care advice and guidance
Q: Exhaust issue? on 2002 Volkswagen Jetta
My car sounds like a motorcycle and the exhaust isn't coming out the back like it should,it smells in my car of exhaust ,what could the problem be? I have a 2002 Volkswagen jetta 1.8 t. Makes a popping sound when I start my car.sounds more of a problem towards the front, could there be a hole in the exhaust? Or a clamp that's broke?,the muffler looks OK and isn't dangling
Agree! Is the turbo still spinning up like it should, boost ok?
(Still running ok?)
(Still running ok?)
Well when I drive you can hear the whistling from the turbo but because of the exhaust issue it sounds worse if that makes sense? I'm not good with cars sorry if I'm no making sense lol. But car vibrates,sounds loud. But when I press the gas it takes a little while to pick up speed .and that could be maybe cause of exhaust issue? but once I'm driving at certain speed a steady speed it vibrates, but has good power but will make a weird sound
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Sounds like it needs to go to the muffler shop and have them advise you, we can't hear the noise and they can help.
Thanks will do
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Probably the flex pipe, the piece under engine that connects the engine to the rest of the exhaust. Looks like the exhaust pipe has a piece of webbing in the pipe.
Didn't find what you were looking for?


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Watch Diplo Drop Some Interesting Music Industry Knowledge
Last week, we premiered the video of a string quartet playing "Bubble Butt" by Major Lazer with Diplo in the audience. The video was recorded at the RECESS Music and Ideas Festival at the University of the Pacific in Stockton, California. The festival featured entrepreneurs speaking to students during "study halls," as well as a concert portion. Diplo headlined both parts of the festival.
Below, we've included three of the best YouTube clips of Diplo's study hall session. Along with Bob Moczydlowsky, the Head of Music at Twitter, Diplo discusses major labels and his production process.
According to their biography, "RECESS is a college music and ideas festival that brings together successful entrepreneurs, the coolest new startups, and hottest acts in music to inspire the next generation of world changing entrepreneurs." It is an awesome event that has the power to help college students achieve their entrepreneurial goals. You can find more inspiring and entertaining content on the RECESS YouTube channel: http://www.youtube.com/wearerecess/
Follow Diplo:


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When Willie Martinez debuted as Central Florida's defensive coordinator 10 years ago, the opponent was Eastern Kentucky and the winning performance of a freshman quarterback named Daunte Culpepper was the big story.
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Martinez takes the reins of another defense on Saturday when No. 13 Georgia plays No. 18 Boise State. There will be no easing into his new position.
The Broncos are the top scoring team in the nation over the past five years and rang up an average of nearly 49 points per game last season. You can imagine what Martinez's reaction was when the WAC team came on Georgia's schedule last summer.
"I wasn't really excited," said Martinez, the Bulldogs' secondary coach who replaced Brian VanGorder as defensive coordinator in January. "It is what it is. It's a great challenge and that's how we've got to look at it."
The big challenge for Georgia may be the variety of looks that the Broncos can throw at the Bulldogs. Boise State can line up in as many as 40 different formations.
"It might be more than that," Georgia middle linebacker Tony Taylor said. "The more you can throw at a defense, the more you can try to confuse them and they do it all real good."
Boise State was one of only three teams last season that ranked in the top 20 nationally in both passing offense and rushing offense. The others were Utah and Louisville.
"You've got to defend formations, you've got to defend motions and shifts," Martinez said. "I've said it to a couple of coaches 'It's almost like whatever you like to run on offense, they run it.' They know how to stress a defense."
Just because Boise can throw different looks doesn't mean that Boise State is scoring by a lot of razzle dazzle and smoke and mirrors, Georgia coach Mark Richt said.
"They're more old school than new school," Richt said. "People think they're the type of offense that just slings it all over the field and is a free-wheeling passing game. They're a very physical, zone-running football team that has great play-action."
Said Boise State coach Dan Hawkins: "I think most good football teams can pound the stone a little bit."
Junior quarterback Jared Zabransky ranked 13th in the nation in passing efficiency last year, passing for 2,927 yards while finishing second on the team in rushing with 326 yards and 13 touchdowns.
"The quarterback makes them go," Martinez said. "He's cool and calm and loves to play. He reminds me of a couple of guys in the past I've defended and a couple of those guys are in the NFL."
Zabransky has dangerous athletic ability even if he doesn't have that same type of blazing speed Georgia saw in Arkansas' Matt Jones. Zabransky can run the option and turned on the jets for an 85-yard touchdown run last year against Hawaii.
"He's a great athlete," Georgia defensive tackle Ray Gant said. "He can run. His accuracy has a little question mark beside it, but as far as throwing strength and running ability, he's definitely a threat."
Hawkins acknowledged that his team is at a disadvantage matching up with Georgia's size up front. The Bulldogs should have a decided advantage in speed as well, said Nevada coach Chris Ault, whose team lost to Boise State last season 58-21.
"Georgia's going to have great speed and in particular on their defensive side of the ball," Ault said. "I think Boise will counter that with their offense with their personnel. ... I think they will line up with them and give them everything they want. Georgia, with the great team speed, I don't think Boise has seen a team with that kind of speed in the last couple of years."
Boise State did not have a 1,000-yard rusher last year, but six different players gained 200 or more yards on the season, led by Lee Marks with 968. Six different players had 10 or more receptions.
"Their players are good players," Gant said, "but their scheme is the difficult thing."
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The Columbia Jazz Artist Series will present its 34th annual Big Band Jazz Festival on Friday and Saturday in the Dogwood Theater on the Columbia College campus.
The event will be attended by 16 Northern California high school and middle school jazz ensembles and will include three evening concerts that are open to the public.
The concerts will feature trumpet and trombone legend Mic Gillette along with Los Angles recording artist Mike Rocha on trumpet, big band composer Bob Secor on piano and trumpet and Monterey Jazz festival's Paul Contos on sax and flute.
The college big band will also feature special guests Ken Taylor and Jamie Dubberly on trombones, Clinton Day on bass, Jim Anderson on drums and Mario Flores on congas.
The festival will run from noon to 4 p.m. on Friday and 11 a.m. to 4 p.m. on Saturday with performances by the school groups and workshops with the festival headliners. The Summerville High School band, directed by Jeff Johnson, will be featured at 12:50 p.m. Friday.
Daytime events are free and open to the public.
Friday concerts will begin at 5:30 and 8 p.m. The festival will conclude on Saturday with a large jam session at 3 p.m. and then the evening concert at 5 p.m.
The jam session is free as part of the daytime festival. Evening concerts are $20 with reserved seating.Tickets for the 8 p.m. show Friday will be available at the door. Advance purchase is recommended for the other shows since they are nearly sold out.
The big band will perform a wide variety of selections featuring all of the festival artists including Henry Mancini's "This Had Better Be Tonight" and the Ray Charles hit "Hallelujah, I Love Her So." Also featured will be several vocal selections along with a few swing hits, standards, Latin tunes and Dixieland favorites.
Mic Gillette is widely known for his work as an original member of Tower of Power. He has been a recording artist on hundreds of albums and has toured with Santana, Huey Lewis and the Doobie Brothers.
Mike Rocha toured for a year with the nostalgia Glenn Miller Band and is a regular member of the Five and Dime Band at Disneyland. With the Glenn Miller Band, Rocha traveled to 48 states, three times across Canada and to Japan for a month, performing over 300 shows. After touring, he taught music performance at the San Joaquin Delta College alongside drummer Brian Kendrick and pianist Aaron Garner.
Bob Secor has published more than 300 compositions for band, orchestra and jazz groups. He performs on both piano and trumpet.
Paul Contos is the educational director for the Monterey Jazz Festival and performs and records throughout the world including annual tours of Japan, South America and major European Jazz festivals.


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Atomization Simulation
Hi All,
I am working on my graduate thesis and I would like some help please. I am running a simulation of a pressure swirl atomizer, the fluid is water and existing into air (also, running into high ambient temperature). Than I will be running the same analysis exiting into superheated steam (which is moving in the direction with the spray). My question is:
1. I know I should use a Discrete Phase model analysis, but, should I couple the analysis with another model?
2. Are there any examples (or a tutorials) on how to run this simulation in ANSYS?
Any help would be greatly appreciated.
Thank you all for your attention.
Hope that helps
Does it make since to couple a DPM with a Multiphase model in the analysis where the spray is discharging into moving steam flow?
|All times are GMT -4. The time now is 17:04.


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More than 22m basic-rate taxpayers could see the value of their pension savings cut, due to Gordon Brown's decision to reduce the basic rate of income tax from 22pc to 20pc from April, 2008.
The rate of income tax affects the amount of money savers invest in their pensions, because pension contributions attract upfront tax relief.
Paul Ilott from independent financial advisers (IFAs) Bates Investment Services said: "A reduction in income tax has the effect of reducing the level of gross pension contribution paid into the scheme."
Currently, when a basic-rate taxpayer puts £100 into their pension, it is topped up by £28.21 in tax relief, representing 22pc of the gross total £128.21 contribution.
Mr Ilott said: "If income tax is reduced to 20pc, this will decrease the size of the gross pension contribution from £128.21 to just £125. To maintain the same level of pension saving, investors will need to increase their own contributions by about 2.5pc."
But Tom McPhail of IFAs Hargreaves Lansdown said: "The changes are good for higher-rate taxpayers, because they will get 40pc tax relief on pension contributions, but, in many cases, only pay 20pc tax on the money coming out, assuming they become basic-rate taxpayers in retirement".


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Now, this is kind of a cheater, because I actually finished both of these last month. They're sure gorgeous, though!
From McKenna Ryan's Sea Breeze, my manatee and pelican friends:
I haven't decided if I want to set these as individual mini-quilts like you see on the pattern package (I'm doing the 9) or if I want to assemble them into a unified top. In the meantime, I'm such a quilt nerd that - yes, I did! - I pinned them to the wall!
Quilt ADD in therapy
- Lynette
- Colorado, United States
- Other than my family, the passion of my life is quilting. An eclectic, I love a wide variety of styles and techniques encompassing both machine and hand work. Instagram: lyncc_quilts
Tuesday, February 15, 2011
BOM 3 - Jan & Feb
2 comments:
- sandi collins said...
these are great. manatees are one of my very favorite tgings.
- February 16, 2011 at 3:29 PM
- sandi collins said...
i meant things.typo!
- February 16, 2011 at 3:41 PM
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text: Jered [N] [H](descent ). Son of Mahalaleel and father of Enoch. ( 1 Chronicles 1:2 ) One of the descendants of Judah signalized as the "father" --i.e. the founder-- "of Gedor." ( 1 Chronicles 4:18 ) [N] indicates this entry was also found in Nave's Topical Bible[H] indicates this entry was also found in Hitchcock's Bible NamesBibliography InformationSmith, William, Dr. "Entry for 'Jered'". "Smith's Bible Dictionary". . 1901.


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Dusty is hearing and vision impaired but gets around very well. He does well with small children in small doses. Dusty is very sweet. Likes to go for walks, does well on a leash. He likes his naps too.
If not already, Dusty will be micro-chipped, neutered (if age appropriate), and up-to-date on his shots prior to adoption. If you would like to meet Dusty to see if he is a good fit for your home, please fill out an Adoption Application online.
• We cannot guarantee the age and breed of any dog. We depend on licensed vets and other professionals to provide the best determination, unless the dog arrived with written documentation.
• Puppies not spayed/neutered at the time of adoption due to age will require a $50 refundable sterilization deposit in accordance with Colorado Code of Regulations 8 CCR 1201-11: Part 19-J.
• We reserve the right to refuse an adoption to any person for the well-being of the dog.


text: In June I delivered my Maiden Speech in the Mass. Senate and secured a wide variety of amendments in the Senate's $38.1 billion proposal, including funding for police departments, schools, hospitals and fire departments in my district as well as increase services for vulnerable and under-served populations statewide. I also sponsored a proposal for early screening for dyslexia in addition to other important legislation. Click below to read the June newsletter.


text: mjbelen View Public Profile Find all posts by mjbelen Cool Cruiser 918 Posts Joined Feb 2001 #19 Lake Worth, FL 918 Posts Joined Feb 2001 Posted August 16th, 2005, 08:08 AM BillnBobbi, I am really enjoying reading your review. I look forward to your next posting. I can't wait to hear what you have to relate about your tour in Florence. I am torn between going to Florence and Piza since I have never been there, or going to the countryside to see the old villages. Joan Expand Signature Collapse Signature Emerald Seas, Flavia, Sunward II, Dolphin IV, Britanis, Seabreeze, Royal Majesty, Leeward, Enchantment of the Seas (4), Imagination, Sovereign of the Seas, Westerdam, Monarch of the Seas (2), Navigator of the Seas (2), Horizon, Paradise, Coral Princess (2), Explorer of the Seas, Radiance of the Seas, Summit (2), Millennium, Carnival Liberty, Liberty of the Seas (2), Caribbean Princess (2), Oasis of the Seas Naming Ceremony, Oasis of the Seas Labadee Extravaganza, Crown Princess, Oasis of the Seas-Eastern Caribbean, Celebrity Reflection, Serenade of the Seas Joan RCL DIAMOND MEMBER GO GATORS


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Inter Milan Wins the Champions League: Thoughts about Vintage Technology
by Andrea Di Maio | May 23, 2010 | 5 Comments
I am not fanatic about soccer, although it is the most important sport in my country. I became a soccer fan in 1965, when I was a little kid, not even a first-grader, and watched Inter Milan win what would have been its last Champions League until yesterday. After that, what looked like an invincible team entered a very long period of relative mediocrity, winning few Italian Leagues but never shining in Europe.
Of course I am happy that my favorite team won, but I am not one of those who went to downtown Milan to watch the game on megascreens with thousands of other people, nor did I wait for the team to return from Madrid (where the match was played) and raise the cup at 6 am today in front of 35,000 ecstatic (albeit sleepy) fans. Actually, as the rest of my family supports the other team from my city (Milan AC), I did not even watch the first 75 minutes of the match on TV (I recorded them on the Sky's version of TiVo) but we watched together a movie on DVD, a tradition we have for when all the members of the family are at home on a Saturday evening.
When I watched the end of the game, I could not resist thinking about how much technology has progressed in the last 45 years. I have blurred memories of a 25 inch black and white TV screen, where only one channel was available (the public TV one), and players could not always wear their traditional blouses because colors would get confused on TV. One had to watch the match live, and there was no TV ad in between actions. images were blurred if compared to high-definition experiences today on a large LCD screen. The sound was squeaky if compared to the crispness of Dolby Digital today.
Also, we would cheer our team in our respective homes and maybe then go and celebrate in the streets, but there would not be thousands of parallel commentaries newspaper web sites, Facebook updates or Twitter streams. There were only the black and white official pictures on the newspaper the day after, and not hundreds of thousand of pictures taken by each soccer fan turned into a reporter with his or her cellphone. There were no large screens downtown for people who could not fly to where the final match was held to experience emotions as if they were at the stadium
So it looks like we have progress a lot and can now see and feel much more than before. A kid today can be in awe by looking at the incredible detail of a tear flowing through his favorite's player cheek as he raises the trophy. Or he could jump onto Facebook and cheer with classmates and watch pictures posted by a friend who was lucky enough to be in Madrid.
But have we lost anything in the process? Were our emotions different and perhaps more intense when we could not see, hear and know everything instantly? For what I can remember, my imagination played a great role in fixing the 1965 victory in my memory forever. I could barely distinguish some of the players' faces and there was no post-match series of live interviews. I did not know what the players were doing at every moment of that historical day.
So I imagined. The same way you imagine the characters in a book, the same way you connect the different parts of a story of which you are told only a few fragments. I am sure that every kid that day saw and remembered a different match, he imagined a different course of action, and imagined how his favorite player would spend the time straight after the match. And he would remember the goals from the single action (and one replay) he saw on TV, rather than watching them over and over again from multiple angles at the touch of a button. But those goals would remain as a myth in his mind, while today's kids' memories will be wiped out by millions of other events like this.
Maybe the very crispness of today's information is what is killing its poetry.
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Thoughts on Inter Milan Wins the Champions League: Thoughts about Vintage Technology
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great point Andrea: I remember a friend of mine saying that he never watched matches on TV but listened to them on the radio instead "because the pictures were better"
Congratulations. I have the same feelings when Real Madrid won the 7th title after many years of disappointments. From B/W memories to colourful images, I wonder which one of the memories I would choose if I was obliged to choose one.
I am not sure I agree. It seems like the eternal "things used to be better discussion". I think we forgot the many "wait, wait, what just happened" moment during B/W TV, and only remember the romantic moments. I prefer today's coverage with multiple angles, because you can better understand position play, crawl under the skin of the keeper that just tips the ball, and have a more intense experience AT THE MOMENT. Instead of cherishing the memory. One intensity traded for the next I guess…
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Leslie and I had another "craft day" and one of the many things we made was a project that used the same Pebeo Porcelaine 150 paints that I had used before when decorating some bowls (that project page is here, which also includes a series of emails about the food-safety of using these paints) to decorate some glass plates I bought to play around with.
Pebeo Porcelaine paints can be found at Dick Blick (their catalog is great), and I got mine at the local Michael's shop.
This is the plate Leslie made:
…and this is the plate I made:
I'm going to keep mine in my craft area – the paint is completely set (even safe to go in the dishwasher) after 35 minutes in a 300* oven. I think they came out really nice!
Another idea I had was to take some more of the clear glass plates and paint in reverse, on the bottom side of the plate. This way, there's no paint at all on the top of the plate where food would be, which would be *completely* safe to serve on…I might try that this week or next.
Oh! And I hope all of you that celebrate Christmas had a really wonderful holiday!


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916 Lewis Avenue, St. Joseph MI, 49085
Sold Price:
3 beds , 1 Full/1 Half baths
1,703 sqft
Status: Closed
Last Updated: 11/20/2017 3:09 PM
Description for 916 Lewis Avenue St. Joseph, MI 49085
GREAT FAMILY HOME on Quiet Cul-de-sac in St Joseph City less than 5 Minutes from Downtown and Beach. Recently remodeled Kitchen w/high end appliances.Both Baths totally rehabbed.Full Bath w/HEATED FLOOR, Clawfoot Tub, Spa Shower.Many Hi-Efficiency Windows. Original Wood Floors on First Flr and New Carpet in 2 of 3 upper bedrms. ALL bdrms have Walk-in Closets. Home has tons of natural light. Lg Front Porch just needs your Rockers.Backyard fenced for kids/pets. Newer driveway w/entry sidewalk. Notice the unique pull-out storage under the stairs in the foyer. Many upgrades make this a very special home. Sfge taken from 2015 apprsl and should be verified by buyers agent/buyer. Duet Washer/Dryer are Neg.
Sold Price:
Sold Date:12/04/2015
St.Joseph City
1 Full/1 Half
1,703 (approx)
Listing Information
St.Joseph City
Public Sewer
School Information
Room Information
Laundry Room
Interior Features
Dishwasher, Microwave, Range, Refrigerator
Ceramic, Wood
Central Air
Gas Heat, Forced Air
Basement, Full
Screened, Storm Window
Wood Floors
Exterior / Lot Features
38' x 128'
Sidewalks, Paved Road, Public Roads
Driving Directions
From Napier Ave (by CVS),go North on Niles Ave approx 4 blocks (toward downtown) to Lewis Ave, turn East on Lewis to sign in Second block. Ravine is at end of street.
Financial Considerations
Listing Price History
St. Joseph Real Estate
St. Joseph is located in Michigan. St. Joseph, Michigan 49085 has a population of 8,286.
The median household income in St. Joseph, Michigan 49085 is $52,772. The median household income for the surrounding county is $44,701 compared to the national median of $53,482. The median age of people living in St. Joseph 49085 is 44.2 years.
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The commitment of IAB Ireland and its members to effective self regulation can be seen in the very high sign up to the IAB Europe Online Behavioural Advertising Self Regulatory Framework. Ireland had the highest number of companies per capita sign up to the OBA framework at its launch in April 2011.
Want to understand how Online Behavioural Advertising works? View our Video here.
The IAB Europe OBA Framework is based upon 7 key principles for online behavioural advertising: notice, user choice, data security, sensitive segmentation, education, compliance and enforcement, and review. An objective of the IAB Europe OBA Framework is to secure the future of Online Behavioural Advertising as an effective business practice in the toolbox of marketers, by ensuring that internet users can understand and control the OBA choices they make online. The IAB OBA programme has evolved in constant dialogue with the European Commission, and Director-General Robert Madelin
The European Advertising Standards Alliance (EASA) is the single authoritative voice on advertising self regulation issues. The EASA Best Practice Recommendation on Online Behavioural Advertising builds on the IAB Europe OBA Framework and provides an industry-wide standard for OBA, ensuring that the entire advertising ecosystem is covered. With the adoption of the Best Practice Recommendation, national advertising self-regulatory organisations commit to applying self-regulatory standards for OBA, integrating the principles of the recommendation into their Codes, and handling complaints thereon. ASAI as a member of EASA adopted the OBA framework as part of its self regulatory remit in September 2013.
The European Interactive Digital Advertising Alliance (EDAA) is a non-profit organisation based in Brussels and is responsible for enacting key aspects of the self-regulatory initiative for Online Behavioural Advertising (OBA) across Europe. EDAA principally acts as the central licensing body for the OBA Icon and provides technical means for consumers to exercise transparency and control over OBA through the www.youronlinechoices.eu online consumer choice platform. EDAA is governed by EU-level organisations which make up the value chain of OBA within Europe and acts to ensure pan-European consistency in approach.
IAB Members may download a report on the first year's activity of the EDAA in EDAA First year of Activity Report Click Here


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Thanks to the awesome and amazingly great Garage Clothing... I spent the past weekend with my best friend at Coachella! We watched everyone from Daughter to Outkast, and it was incredible. We ate everything from grilled cheeses to watermelon, and even drank from coconuts. It was truly one of the best weekends of my life.
Deciding what to wear each day is always difficult, but Garage was a one stop shop for all our festival needs. Day 1, I decided to wear a matching floral two piece set with my rimmed hat to top it off! It was light and breezy which is perfect for the festival heat. Day 2, Madeline had a brilliant idea of tying up a low back sweater shirt and pairing it with a bandeau underneath. I threw in my brown leather backpack with feather accents for a bit of a hippie vibe. Day 3, we were so tired and just wanted to lay in the grass all day so I wore a tribal skirt and tie up halter crop which was so comfortable and also perfect for laying down in the grass 😉
We danced and laughed and cried. We saw our favorite bands and discovered some new ones. Music is what brought us together as friends, and it still a core part of our friendship. We don't just love music. Music is apart of who we are.
"I was born with music inside me. Music was one of my parts. Like my ribs, my kidneys, my liver, my heart. Like my blood. It was a force already within me when I arrived on the scene. It was a necessity for me-like food or water." - Ray Charles
Day 1 Day 2 Day 3
Kimono Bandeau Tribal Maxi Skirt
Shorts Shorts Halter Crop
Bandeau Sweater Tank
Thanks to Garage Clothing for making it all possible! See you next year! 😉


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With summer clearly in sight, light wash denim has been on my radar more than ever. While escaping the city with Toyota to attend the Sasquatch Music Festival over Memorial Day weekend, I was excited to break out my latest denim find: a light wash denim mini skirt. I opted to pair my light wash denim mini skirt with a long sleeve bodysuit and espadrilles. It has definitely been a minute since I last wore a denim skirt in this style. Embracing the denim mini skirt was a bit a of '90s revival for me. However, after a day in the gently faded denim mini skirt, I am a believer once again. The lived-in fading and subtle frayed hem made the leg-flaunting denim miniskirt so fun to wear. It is definitely a wear-with-everything piece, which is exactly why you need a denim mini skirt this summer.
To my excitement, the weather in Central Washington was beautiful – it just took a three hour car ride to find it! During the day, I explored the city of Quincy, Washington. It was my first time visiting. What struck me the most was the contrast in scenery. The desert-like landscapes and breathtaking canyons had me feeling like I was in Utah or even Sydney, Australia's wine country (Hunter Valley) minus the kangaroos! This was even more true when I stumbled upon Cave B winery! So, of course we stopped for a quick wine tasting before heading to the music festival. Hope you caught it all on Snapchat! If not, make sure to add me on Snapchat! Username: sarahstylessea.
If you are loving this skirt, I have linked to more outfits featuring denim here. As always, don't forget to follow me on Instagram or SIGN UP to receive new posts by email!! xo, Sarah.
- Light Wash Denim Mini Skirt
- Akira Long Sleeve Bodysuit with Tasseled Rope Neckline
- Capwell Statement Collar Necklace (shop similar from Bluefly)
- Marc Fisher LTD Randall Leather Sandals in Dark Taupe (available at Nordstrom and Zappos)
- Ray Ban 50mm Rounded Sunglasses


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Hey everyone,
This week, we have DJ/Producer duo, SLANDER, in the house for a guest mix. Currently on the last leg of their US tour, they made some time to give us a dope guest mix this week. They have multiple releases on OWSLA, Mad Decent and Interscope which I have played in past shows.
Bill Withers – Ain't No Sunshine (Lido Remix)
Flume – Smoke & Retribution (Ekali Remix)
What So Not – Gemini (feat. George Maple)
Bishop Briggs – River (BURNS Remix)
K.Flay – Blood In the Cut (Aire Atlantica Remix)
RL Grime – TELL ME (MIKEWASHH REMIX VS RUDEBRAT REFIX)
Excision X Space Laces – Throwin' Elbows (Original Mix)
Benny Benassi – Cinema (Sullivan King Rework X Luca Lush Flip)
Borgore x G-Eazy – Forbes (Sullivan King Remix)
Team Bayside High – Rock The Bells (Holiday Trap / Short Edit) – 6A
blur – Song 2 (TAITO Bootleg Remix)
Herobust – WORK (BARELY ALIVE REMIX)
Fitz and the Tantrums X Flux Pavillion – Handclap X I Cant Stop (Jeremiah Red Edit)
Skrillex X RL Grime X WHAT SO NOT – Waiting (Julius C. Flip)
Killers – Mr. Brightside (Two Friends Trap RMX)
Rae Sremmurd – Black Beatles (MAKJ Trap Remix )
Sullivan King – Want
Twenty One Pilots – Heathens (Joe Maz Twerk Remix)
Follow Slander
Instagram: @SlanderOfficial
Snapchat: @SlanderOfficial
Got a cool Remix of a KROQ song? Send it over! Ill check it out!
Instagram: @djjeremiahred
SnapChat: DJJeremiahRed


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My Favorite Movies of All Time
These are my all time favorite movies, all inclusive, movies Ive seen on TV and in a theatre.
Log in to copy items to your own lists.
Raiders of the Lost Ark (1981)
Archaeologist and adventurer Indiana Jones is hired by the U.S. government to find the Ark of the Covenant before the Nazis. (115 mins.)
Stars: Harrison Ford, Karen Allen, Paul Freeman, John Rhys-Davies
" An incredible thrill ride, funny, exciting and in my opinion, the greatest action movie ever made! " - mikeCubbie69
The Right Stuff (1983)
The story of the original Mercury 7 astronauts and their macho, seat-of-the-pants approach to the space program. (193 mins.)
Director: Philip Kaufman
Stars: Sam Shepard, Scott Glenn, Ed Harris, Dennis Quaid
The Best Years of Our Lives (1946)
Three World War II veterans return home to small-town America to discover that they and their families have been irreparably changed. (170 mins.)
Director: William Wyler
Stars: Fredric March, Dana Andrews, Myrna Loy, Teresa Wright
" A movie that somehow seems to get better with every showing, ahead of its time, heartbreaking, incredibly moving and ultimately triumphant. Harold Russells performance as the armless returning vet is just amazing. " - mikeCubbie69
Amadeus (1984)
The incredible story of Wolfgang Amadeus Mozart, told by his peer and secret rival Antonio Salieri - now confined to an insane asylum. (160 mins.)
Director: Milos Forman
Pinocchio (1940)
A living puppet, with the help of a cricket as his conscience, must prove himself worthy to become a real boy. (88 mins.)
Director: Norman Ferguson, T. Hee
Stars: Dickie Jones, Christian Rub, Mel Blanc, Don Brodie
" My all time favorite animated film, beautifully drawn, poignant and warm hearted, its just an incredible piece of work from the Golden Age of Disney " - mikeCubbie69
The Godfather (1972)
The aging patriarch of an organized crime dynasty transfers control of his clandestine empire to his reluctant son. (175 mins.)
Director: Francis Ford Coppola
Stars: Marlon Brando, Al Pacino, James Caan, Diane Keaton
The Godfather: Part II (1974)
The early life and career of Vito Corleone in 1920s New York is portrayed while his son, Michael, expands and tightens his grip on the family crime syndicate. (202 mins.)
Director: Francis Ford Coppola
Stars: Al Pacino, Robert De Niro, Robert Duvall, Diane Keaton
Pulp Fiction (1994)
The lives of two mob hit men, a boxer, a gangster's wife, and a pair of diner bandits intertwine in four tales of violence and redemption. (154 mins.)
Director: Quentin Tarantino
" An offbeat homage to gangster films that breaks most of the rules of standard filmmaking, extended conversational dialogues, time frame that is turned around on itself and the threat of violence that doesnt actually happen. Great performances from familiar actors. " - mikeCubbie69
Schindler's List (1993)
In German-occupied Poland during World War II, Oskar Schindler gradually becomes concerned for his Jewish workforce after witnessing their persecution by the Nazi Germans. (195 mins.)
Stars: Liam Neeson, Ralph Fiennes, Ben Kingsley, Caroline Goodall
" Stephen Spielbergs Holocaust masterpiece. Filmed in stark B/W, its an incredibly moving and compelling film. " - mikeCubbie69
Groundhog Day (1993)
A weatherman finds himself inexplicably living the same day over and over again. (101 mins.)
Director: Harold Ramis
Raging Bull (1980)
An emotionally self-destructive boxer's journey through life, as the violence and temper that leads him to the top in the ring destroys his life outside it. (129 mins.)
Director: Martin Scorsese
Stars: Robert De Niro, Cathy Moriarty, Joe Pesci, Frank Vincent
Duck Soup (1933)
Rufus T. Firefly is named president/dictator of bankrupt Freedonia and declares war on neighboring Sylvania over the love of wealthy Mrs. Teasdale. (68 mins.)
Director: Leo McCarey
Stars: Groucho Marx, Harpo Marx, Chico Marx, Zeppo Marx
She Wore a Yellow Ribbon (1949)
Captain Nathan Brittles, on the eve of retirement, takes out a last patrol to stop an impending massive Indian attack. Encumbered by women who must be evacuated, Brittles finds his mission imperiled. (103 mins.)
Stars: John Wayne, Joanne Dru, John Agar, Ben Johnson
Raising Arizona (1987)
When a childless couple of an ex-con and an ex-cop decide to help themselves to one of another family's quintuplets, their lives become more complicated than they anticipated. (94 mins.)
Director: Joel Coen
Stars: Nicolas Cage, Holly Hunter, Trey Wilson, John Goodman
Star Wars: Episode V - The Empire Strikes Back (1980)
After the rebels are overpowered by the Empire on their newly established base, Luke Skywalker begins Jedi training with Yoda. His friends accept shelter from a questionable ally as Darth Vader hunts them in a plan to capture Luke. (124 mins.)
Director: Irvin Kershner
E.T. the Extra-Terrestrial (1982)
A troubled child summons the courage to help a friendly alien escape Earth and return to his home world. (115 mins.)
Stars: Henry Thomas, Drew Barrymore, Peter Coyote, Dee Wallace
Singin' in the Rain (1952)
A silent film production company and cast make a difficult transition to sound. (103 mins.)
Director: Stanley Donen, Gene Kelly
Stars: Gene Kelly, Donald O'Connor, Debbie Reynolds, Jean Hagen
The Awful Truth (1937)
Unfounded suspicions lead a married couple to begin divorce proceedings, whereupon they start undermining each other's attempts to find new romance. (91 mins.)
Director: Leo McCarey
Stars: Irene Dunne, Cary Grant, Ralph Bellamy, Alexander D'Arcy
The Grapes of Wrath (1940)
A poor Midwest family is forced off their land. They travel to California, suffering the misfortunes of the homeless in the Great Depression. (129 mins.)
Star Wars: Episode III - Revenge of the Sith (2005)
Three years into the Clone Wars, the Jedi rescue Palpatine from Count Dooku. As Obi-Wan pursues a new threat, Anakin acts as a double agent between the Jedi Council and Palpatine and is lured into a sinister plan to rule the galaxy. (140 mins.)
Director: George Lucas
No Country for Old Men (2007)
Violence and mayhem ensue after a hunter stumbles upon a drug deal gone wrong and more than two million dollars in cash near the Rio Grande. (122 mins.)
Director: Ethan Coen, Joel Coen
White Heat (1949)
A psychopathic criminal with a mother complex makes a daring break from prison and leads his old gang in a chemical plant payroll heist. Shortly after the plan takes place, events take a crazy turn. (114 mins.)
Director: Raoul Walsh
A Night at the Opera (1935)
A sly business manager and two wacky friends of two opera singers help them achieve success while humiliating their stuffy and snobbish enemies. (96 mins.)
Director: Sam Wood
Stars: Groucho Marx, Chico Marx, Harpo Marx, Kitty Carlisle
The Searchers (1956)
An American Civil War veteran embarks on a journey to rescue his niece from the Comanches. (119 mins.)
Stars: John Wayne, Jeffrey Hunter, Vera Miles, Ward Bond
The Wizard of Oz (1939)
Dorothy Gale is swept away from a farm in Kansas to a magical land of Oz in a tornado and embarks on a quest with her new friends to see the Wizard who can help her return home in Kansas and help her friends as well. (102 mins.)
Director: Victor Fleming
Stars: Judy Garland, Frank Morgan, Ray Bolger, Bert Lahr