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I remember as a kid that I couldn't wait to get my Easter basket and tear into the Reese's Peanut Butter Eggs. They were the best candy the Easter Bunny brought. I mean they are like giant Reese's Peanut Butter Cups, maybe they're the same size but there is a lot more peanut butter in them than in the cups so of course I love them!!! I remember when I first had these No Bake Chocolate & Peanut Butter Bars I thought they were just like a Reese's Peanut Butter Cup but in bar form. When I was thinking about what I wanted to make for a fun Easter treat I decided it had to be these Homemade Reese's Peanut Butter Eggs.
They're very easy to make and don't require any baking. If you melt the almond bark in the microwave it's even easier to have the little monkeys in the house help. Most of the time in this recipe is inactive. you want the mixture to be very cold when you form it and again before you dip it in the hot chocolate. The actual active time is very much. The kids couldn't wait to taste these and, of course, they all loved them!! I think that these Homemade Reese's Peanut Butter Eggs will become a new Easter tradition in our house!
- 1 cup butter, melted
- 2 1/4 cups graham cracker crumbs
- 2 cups powdered sugar
- 1 1/4 cup creamy peanut butter
- 12 oz. chocolate almond bark
- 1 tbsp vegetable shortening
- in a medium bowl combine the butter, graham cracker crumbs, powdered sugar and peanut butter
- refrigerate the mixture for 1 hour
- once mixture has hardened form 2 tablespoons of mixture into an egg shape and place on a parchment lined baking sheet
- place into the freezer for 30 minutes
- after peanut butter eggs have hardened
- melt almond bark and vegetable shortening in a medium bowl
- dip peanut butter eggs into the melted chocolate and set on parchment paper
- allow chocolate to harden and enjoy!


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Calling all young composers – the BBC Proms Inspire Competition is offering you the chance to have your music performed at the BBC Proms.
Since its inception, the Inspire scheme has offered a platform for over 900 young composers aged 12-18 from across the UK to develop their skills, share their ideas and get their music heard.
In 2017 the scheme continues to offer emerging composers new opportunities and year-round events to encourage and support their development.
The BBC Proms Inspire Competition for young composers offers winners the opportunity to have their composition performed by professional musicians at the BBC Proms, the world's largest classical music festival, and broadcast on BBC Radio 3, as well as a coveted BBC commission.
The judging panel for the 2017 Inspire Competition is made up of renowned composers including Mark-Anthony Turnage, Kerry Andrew, Charlotte Bray, Hannah Kendall and Fraser Trainer as well as BBC Proms director, David Pickard.
Past competition winners and highly commended composers are also invited to join the team of Inspire ambassadors, who act as a sounding board and champion the work of the Inspire scheme across the UK. The 2017 Inspire ambassadors are Sarah Gait, Electra Perivolaris, Grace Mason, Sofia Swenson-Wright, Tammas Slater, Thomas Brown, Alex Jones, Ellis Howarth, Max Bilbe, William Kidner and Sarah Jenkins.
David Pickard, BBC Proms director, said: 'The BBC Proms Inspire scheme is a unique gateway for young composers wanting to develop their talent and find a showcase for their work. I am thrilled by Inspire's continuing growth and the enthusiasm and talent of those who take part.'
Sarah Jenkins, Inspire ambassador, said: 'Being a part of the BBC Proms Inspire scheme has opened up incredible opportunities to work alongside professionals and other young composers, as well as increasing my confidence and love for music – I would truly encourage anyone with a passion for composing to apply.'
The search for the 2017 Inspire Competition winners is now open with the closing date for entries Thursday 25 May.
Visit the BBC website to make your submissions.

subset: commoncrawl


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Here at Gadget Advisor, we are big fans of the classic Nintendo games, such as Dragon Warrior, Final Fantasy, and Super Mario Bros series. When you have played a certain gaming console more than any other, you get used to its controller. For those most comfortable with the classic NES controller, the Compwnent USB Nintendo NES Controller is ideal for PC game-play. We have used a similar solution from another company, but sadly, the controller developed a problem over time, and by then the company who sold it was no longer offering them. Therefore, it's great to see a new option for NES USB controllers. The controllers are not being mass produced, though. So, act fast. As of now, the the NES controllers can be purchased for $33.
Game Console
Nintendo has officially announced an upgrade to the DS portable gaming console. It is called the DSi, maintaining the trademark double-screen (DS). The new unit features a larger 3.5" display, while becoming 12% thinner than the previous DS model. The DSi does not include a GBA cartridge port, which means the console can no longer play GameBoy and GameBoy Advance games. Otherwise, the DSi is extremely feature-packed, including cameras, paint software, advanced web browser, music playback, SD slot, internal storage, and more.
The DSi will launch on November 1st (Japan) with a cost of ¥189,000 (about $178 USD), which is in-line with the current DS model. Dates for International releases have not yet been announced.
As we utilize more and more electronic devices in the digital home, controlling them becomes an important issue. No one wants to keep up with or sort through a dozen different remotes for various devices in a home entertainment system and surrounding electronic equipment. The Logitech Harmony Universal Remote Control is the perfect solution. After reviewing numerous different remote control options and actually using Logitech Harmony remote controls for years, I can whole-heartedly recommend the Logitech Harmony remote control to anyone seeking a solution. I prefer the 880 model's buttons and additional display items, while others prefer the touch-screen and interface upgrades of the Harmony One. However, both remotes use the same intelligent system, making either an excellent choice.
Both models support 15 or more devices. The device database is extensive, and is perfect if you have lost a remote control or have a damaged remote. Otherwise, you can also program a device from an existing remote control. The setup wizards are intuitive and enable easy setup of devices.
One-touch operation is provided for operation, including turning on a device and any other component(s) that may be required to use it (such as turning on a TV also when playing a DVD). Buttons can be customized for specific tasks. Backlighting is provided for the buttons as well as the LCD display. The remotes are also rechargeable via the charging station, with low battery notification available when in use.
The device compatibility for the Harmony remotes is incredible. You can control a televisions, satellite or cable box, DVD player, video recorder, digital media player, TiVo or other PVR, game console, amplifier, stereo, or even a PC or home automation setup. More than 5,000 brands and 225,000 devices are supported.


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Pursuing Early Financial Independence through Dividend Growth Investing and other Passive Income.
Monday, February 11, 2013
Recent Buy
Since Aflac is going ex-div on Wednesday I'll be receiving their next dividend payable on March 1st. Unfortunately this won't be diversifying my dividend payouts since most of the companies I own pay on the Mar, Jun, Sept, Dec schedule but I'm not worried about that yet. This most important part is investing in solid companies that have great prospects to continue raising the dividend. The YOC for my entire FI portfolio remained the same, but for my non-ESPP share portfolio it lowered from 3.22% to 3.20%. My forward 12 month dividends for my FI portfolio now sits at $1,890.20. This is over 10% coverage of my total expenses from 2012.
Aflac has been on my radar for a long time and I've been kicking myself for not picking some up in the $30's or $40's. I was debating myself as to whether I should sell a put to start my position or if I should go on and purchase some shares, especially since there's some pretty enticing put options giving 10%+ annual returns or cost basis' in the $48 range. Since I hadn't made an outright purchase yet in 2013, I decided to go on and pick up some shares. I still might sell a put in the future, but I think the market is at least due for a breather if not a pullback so I'm holding some more cash rather than getting it working right away.
I've updated my portfolio to reflect the new purchase.
20 comments:
I really like AFL as well. Next correction I planned to pick up a couple insurance companies.ReplyDeleteReplies
I really like AFL long term, still can't believe I never picked some up before. I got a little worried about all the talk of their PIIGS investments. I have no problem adding some more if we get some more weakness.
Thanks for stopping by!
I still regret picking up TWGP instead of a larger company like AFL. I'm giving TWGP until the end of the year to raise their dividend , if they don't I will likely pick up another insurer like AFL. Nice purchase!ReplyDeleteReplies
I'm with you on TWGP. I've been going back and forth on whether I should dump them now or not. I've been leaning towards waiting to see about the dividend, if I think there's a good chance of it not being raised then I'll unload them. Hopefully Mr. Market will give us a chance to add some in the $40's. There's some pretty good put options for AFL so I might be selling one soon.
Thanks for stopping by!
Nice pickup, and congrats on the >10% of your living expenses! That is really a big step!ReplyDeleteReplies
It's great to see that without any further investment I'd have 10% of my expenses covered. Pretty big milestone. I'm hoping to be around 20% by the end of the year.
Thanks for stopping by!
Good buy. It's hard to resist stocks after a fall like AFL took.ReplyDeleteReplies
Headed Home,Delete
I'll gladly welcome another fall from here though, if not then it'll be put option selling. I like when Mr. Market goes crazy on the pricing of some stocks due to no real reason, like NSC's big drop last year. CAT and CMI's drops also gave me a chance to own some great companies with decent starting yields.
Thanks for stopping by!
I really like AFL. I own a bunch already. I bought it back in 2011 when the market fell off a cliff during the first round of debt ceiling idiocy. I wouldn't mind buying a bit more in the future.ReplyDeleteReplies
I still can't believe I didn't pick any up a few years back. I'd like to add more to the position, possibly through selling puts. Of course if the sequestration talks come to a standstill we might get some more volatility dropping some prices for all of us.
Thanks for stopping by!
Great purchase here. I recently picked up some additional shares and I feel it's one of the better picks in the financial space currently. A dividend champion with a low valuation, solid balance sheet and strong brand name.
Great job on getting to 10% of your expenses being covered by dividends. That's awesome!
Best wishes.Replies
Everything you mentioned is a great reason to own them. I expect that high DG to continue on for several more years.
It's nice to see the 10% coverage, although there's still a lot of work to do to get to 100%. But it's one milestone along the way checked off.
Thanks for stopping by!
PIP - Most of the dividend growth investors seem to be a big fan of this one, and I have put it on my watch list. My US portfolio is full, so I would have to bump something out to add AFL, and there is nothing I want to swap yet - although I have warned MSFT it will be sleeping in the shed if its performance doesn't improve soon :)ReplyDeleteReplies
Well AFL is really more of a play on Japan, since most of their revenue is from the Japanese market. If I remember correctly it's around 75% JPN, 25% US.
Thanks for stopping by!
I think AFL will be a nice dividend growth stock. I'd like to get back into the insurance industry which I exited a few years ago when HGIC was acquired.ReplyDelete
My main concern with Aflac is all the long term bonds they hold. I'm just not sure I'm comfortable with billions in bank bonds (and even airline bonds o.O) I wouldn't hold them myself and at this point I'm just not sure I want my companies to hold them either. I do think the stock is undervalued though and might eventually have a spot in my portfolio.Replies
Considering the amount of growth they have ahead of them, both in earnings and dividends to follow, I feel the value is definitely there. They're Euro exposure is what kept me from investing earlier, but they've been taking the right steps to limit the potential downside.
Thanks for stopping by!
Love the pick up! I actually got into AFL in the high 30's. I did all my metric research and couldn't figure out why it was trading so low, but it was at the beginning of the Europe crisis (or at least when it hit mainstream news) and they have a ton of their bonds in EU.ReplyDelete
You said you hit 10% of expenses - your living expenses are only 20K per year?Replies
I should have started my position then, but those prices probably won't be seen again anytime soon. The Euro bonds were the main reason I stayed away from investing in AFL.
My living expenses for 2012 came in at just over $18k. That includes my rent, utilities, food, gas, car insurance and maintenance. Just the basics that I would need although if absolutely necessary I wouldn't mind cutting the car expenses. Even without a car payment it's still very expensive to keep. It doesn't include any travel/entertainment but before I call it quits I'll have a cushion to protect against possible dividend cuts, required expense coverage and then some fun money.
Thanks for stopping by!
I love AFLAC. It's a free cash flow king, trading at only 2 or 3 times FCF. I wrote an article about how some of it's assets are reported as liabilities, per GAAP standards. http://seekingalpha.com/article/1032911-aflac-s-hidden-source-of-valueReplyDeleteReplies
Thanks for stopping by! I think it's your first visit, or at least first comment. There's plenty to like about AFL. I remember reading your article about AFL, it was another thing that helped sway me to jump in.


text: Ok, I have decided to take the plunge and have a tank built. Size will be 30x24x24 glass with a water level of about 20 inches. The back will be drilled to support returns and drains and that is where I am just a bit stuck. For return I figured one will do and cover it with a screw in basket that I have seen on some drains. My isssue is with the drains, what would be the best solution to keep them inside the tank? I was thinking about standard over flow and filling it with sponge. Or I have read where somme use gutter guard, size depending on Octo. I do not know species but will go for one of the larger ones. Pictures speak many words if you can please. Thanks Craig


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**Please share your favorite Etsy Crafty Party 2013 memory in the comments. Also, we like you.**
On June 20, 2013, Ugly Baby and La Ru hosted a birthday party for Etsy. There are parties around the country - and Internationally - on Etsy's birthday and we were excited to play host for the only party in Washington state. Heck yeah!


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New York, New York (PressExposure) March 08, 2011 -- Want a tattoo that's going to leave a lasting impression, but not one that's leaves a permanent mark on your skin? Well, put your fears to rest, because that's where Harlem Family Tats comes to the rescue. They not only promise you a great looking tattoo, but they have now lowered their prices for all gigs booked Monday through to Thursday online.
"This price-break promotion is specifically directed at schools or special events during the week," said Mr. Spence, a specialist airbrush temporary tattoo artist.
These temporary airbrush tattoo artists, who serve the New York, Long Island, New Jersey, and CT tri-state area, has on offer more than 500 airbrush tattoo designs.
"We offer lots of tattoo designs to choose from including tribal, kids, and henna like selections. However, with advance notice, we can also provide personalized temporary tattoos or stencils," said Mr. Spence, who claimed that their work is temporary and safe, painless, and affordable.
Decided you don't want an airbrushed tattoo? Well, these airbrush tattoo artists are certainly accommodating and will heed to your every request, whether it be a uniquely designed or faked tattoo, which only take a few minutes to apply, and can last up to one week with proper care.
According to the company's spokesperson, all their temporary tattoo paints are durable, dry instantly, yet easily removed. Besides, their tattoo paints will not rub off on your clothes. "These temporary tattoos are so easy to removed, all it takes is baby oil or rubbing alcohol to accomplish the disappearing act," said Peter Spence.
These experienced tattoo artists have airbrushed thousands of designs and interact well in all settings with all ages. And as the number-one tri-state temporary airbrush tattoo artists, they specialise in special offering tattoos for special events, such as, Sweet 16's, holiday parties, birthday parties, or bar mitzvahs.


text: "The Eastern Mediterranean and the Making of Global Radicalism is the perfect antidote to the deterministic histories that have for so long obscured how the Middle East came to modernity. Khuri-Makdisi rightly argues that it was both more complex and more open to the outside influences than either nationalist historians (who see only the state) or the partisans of the new orientalism (who see only Islam) have been willing to admit. This book has been badly needed for some time."Edmund Burke III, co-editor of The Environment and World History


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Ansamycin antibiotics, such as 17-allylaminogeldanamycin (17-AAG), bind to Hsp90 and regulate its function, resulting in the proteasomal degradation of a subset of signaling proteins that require Hsp90 for conformational maturation. HER2 is a very sensitive target of these drugs. Ansamycins cause RB-dependent G1 arrest that is associated with loss of D-cyclins via a PI3 kinase, Akt dependent pathway. Downregulation of D-cyclin was due, in part, to loss of Akt expression in response to drug. Moreover, in HER2 overexpressing breast cancer cells, 17-AAG caused rapid inhibition of Akt activity prior to any change in Akt protein. Ansamycins caused rapid degradation of HER2 and a concomitant loss in HER3 associated PI3 kinase activity. This led to a loss of Akt activity, dephosphorylation of Akt substrates, and loss of D-cyclin expression. Introduction into cells of a constitutively membrane bound form of PI3 kinase prevented the effects of the drug on Akt activity and D-cyclins. Thus, in breast cancer cells with high HER2, Akt activation by HER2/HER3 heterodimers is required for D-cyclin expression. In murine xenograft models, non-toxic doses of 17-AAG markedly reduced the expression of HER2 and phosphorylation of Akt and inhibited tumor growth. Thus, pharmacological inhibition of Akt activation is achievable with ansamycins and may be useful for the treatment of HER2 driven tumors.
Heat Shock Protein 90 (Hsp90) is an abundant chaperone that plays a role in protein refolding and in the conformational maturation of certain signaling proteins. It contains a conserved pocket in its amino-terminus that binds ATP and ADP with low affinity (Prodromou et al., 1997). Completion of Hsp90-dependent protein refolding is ATP-dependent and involves dissociation of the renaturated protein from the chaperone complex. Ansamycin antibiotics and radicicol are natural products that bind to the Hsp90 pocket and alter its function (Schneider et al., 1996). Exposure of cells to these compounds results in the degradation of a subset of signaling proteins that associate with Hsp90, including steroid receptors and the Raf serine kinase, as well as certain transmembrane tyrosine kinases, including HER2 and met (Czar et al., 1997; Mimnaugh et al., 1996; Schulte et al., 1996; Stancato et al., 1997; Webb et al., 2000; Whitesell and Cook, 1996; Xu et al., 2000). Breast cancer cells that overexpress HER2 are especially sensitive to the anti-proliferative activity of these drugs (P Munster, unpublished data). Based on these and other data, an ansamycin derivative, 17-allylaminogeldanamycin (17-AAG), is being tested in patients with advanced cancer.
The response of tumor cells to ansamycins is dependent upon the status of their RB protein. Ansamycins cause cells with wild-type retinoblastoma protein (RB) to undergo growth arrest in G1 and, subsequently, to undergo apoptosis. G1 arrest is associated with rapid loss in D-cyclin associated kinase activity and hypophosphorylation of RB. Tumor cells with defective RB-function are resistant to induction of G1 block by ansamycins (Srethapakdi et al., 2000). These data imply that effects of ansamycins on G1 progression are confined to pathways upstream of RB and that Hsp90 selectively regulates these pathways.
The sole known substrate of D-cyclin associated kinase is RB, so it is likely the downregulation of the activity of this enzyme by ansamycins explains their effect on G1 progression. These drugs are not direct inhibitors of D-cyclin-cdk4/6 protein kinase but they cause a rapid loss in its intracellular activity associated with decreased expression of D-cyclins and of cdk4. The maturation of cdk4 is dependent upon Hsp90 and this kinase is a direct target of the drug (Stepanova et al., 1996). In contrast, ansamycins decrease D-cyclin levels by downregulating a PI3 kinase, Akt dependent pathway required for their expression (Muise-Helmericks et al., 1998).
The importance of the phosphatidylinositol 3-kinase (PI3 kinase), Akt kinase pathway in maintaining the growth and viability of cancer cells led us to investigate the mechanism through which ansamycins downregulate its function. We found that 17-allylaminogeldanamycin (17-AAG) inhibited Akt function in a complex manner. It caused a slow decline in the expression of Akt protein. This decline was accompanied by a parallel diminution in Akt phosphorylation and kinase activity. However, in breast tumor cells with high levels of HER2, 17-AAG also caused a rapid loss in Akt kinase activity prior to any change in protein expression. This was accompanied by a decrease in the phosphorylation of Akt substrates and a decline in cyclin D1 and D3 expression. The loss of Akt kinase activity was due to rapid dephosphorylation of HER3 in response to degradation of HER2. This led to an uncoupling of the binding of active PI3 kinase to HER3 at the membrane. Introduction into cells of a membrane bound, prenylated form of the catalytic subunit of PI3 kinase rendered the cells insensitive to the effects of 17-AAG on Akt kinase activity and D-cyclin expression. These results suggest that in breast cancers with high levels of HER2, Akt activation is dependent on HER2/HER3 heterodimers and is required for D-cyclin expression. 17-AAG inhibits this pathway by inducing HER2 degradation and by reducing Akt expression, so it may be useful in treating these tumors. Indeed, we showed here that 17-AAG inhibited Akt activation at non-toxic doses and had anti-tumor activity in breast cancer xenografts.
Ansamycins induce the proteasomal degradation of several transmembrane tyrosine kinases, including members of the HER family (Mimnaugh et al., 1996; Xu et al., 2000). We determined whether the expression or activity of PI3 kinase or Akt was also directly affected. 17-AAG had no effect on the activity of either enzyme in vitro or on the intracellular expression of the p85 regulatory or p110 catalytic subunit of PI3 kinase (Figure 1c, data not shown (DNS)).
17-AAG caused a decrease in Akt protein expression in all cell lines examined (Figure 1a, DNS). The effect was detected by 12 h after drug addition and levels were reduced by 80% at 24 h. In most cells, the level of the phosphorylated, active form of Akt fell in parallel with that of the total Akt protein. The data suggest that inhibition of Akt expression by 17-AAG may contribute to its cellular effects.
In addition, in breast cancer cell lines with elevated expression of HER2 (SKBr-3 and BT-474), 17-AAG caused a rapid fall in Akt phosphorylation on serine 473 prior to any decline in Akt protein expression (Figure 1b). Phosphorylation of Akt on threonine 308 was undetectable by Western blot analysis in these cells. Akt phosphorylation and in vitro protein kinase activity fell in parallel beginning 1 h after drug addition and were undetectable by 1.5 h (Figure 1b). The concentration range required for inhibition of activation is 2 – 20 nm and levels were reduced to 30% of controls with 10 nm 17-AAG (Figure 1d).
Akt kinase has been shown to phosphorylate several key substrates that regulate protein translation, apoptosis and cellular proliferation (Marte and Downward, 1997; Vanhaesebroeck and Alessi, 2000). Phosphorylation of two of these substrates, glycogen synthase kinase-3 (GSK-3) and eukaryotic translation initiation factor 4E-binding protein 1 (4E-BP1), can be demonstrated in SKBr-3 cells (Figure 2a). 17-AAG caused dephosphorylation of these proteins at concentrations and times associated with inhibition of Akt activation. Akt has been shown to regulate D-cyclin translation and turnover (Diehl et al., 1998; Muise-Helmericks et al., 1998). In cells exposed to drug, cyclin D1 and D3 expression fell in parallel with Akt activity and dephosphorylation of Akt substrates (Figure 2b).
Akt kinase associates with the plasma membrane by binding to phosphatidyl inositol-3′ phosphates via its pleckstrin homology (PH) domain (Franke et al., 1995). At the membrane, Akt kinase is activated as a result of the phosphorylation of Thr-308 and Ser-473 by 3-phosphoinositide-dependent protein kinase 1 (PDK1) and perhaps other kinases (Alessi et al., 1997). Thus, Akt activation is dependent on PI3 kinase activity.
Ansamycins did not affect the expression of PDK1 (Figure 1c). Furthermore, drug treatment did not affect phosphorylation of PDK1 at Ser-241, a site essential for PDK1 activity (Figure 1c) (Casamayor et al., 1999). As previously described, they do induce the degradation of HER2 (Mimnaugh et al., 1996; Xu et al., 2000); expression was reduced by 90% after 2 h of exposure to as little as 10 nm 17-AAG (Figure 3a). We used 50 nm 17-AAG to ensure maximum inhibition. There was concomitant loss of tyrosine phosphorylation of HER2 (Figure 3a). Activated HER2 forms hetero- dimers with other members of the HER-kinase family and transphosphorylates its dimerization partner (Wallasch et al., 1995). One of these, HER3, has no endogenous tyrosine kinase activity, but contains multiple tyrosines that when phosphorylated are docking sites for PI3 kinase (Hellyer et al., 1998).
After 4 h of treatment, 17-AAG had no effect on HER3 expression, although HER3 levels do decline with longer exposure to drug (Figure 3a and DNS). However, association of HER3 with HER2 declined by 60% after 1 h and 90% after 4 h of treatment. Phosphorylation of HER3 declined in parallel (Figure 3a). Decreased phosphorylation of HER3 led to a coordinate decrease in its binding to the p85 regulatory subunit of PI3 kinase and in its association with PI3 kinase activity (50 – 65% decline at 2 h, 95% decline at 4 h, Figure 3a,b).
One hour pretreatment with lactacystin, a proteasome inhibitor, abrogated the effect of 17-AAG on HER2 protein (Figure 3c). Lactacystin is a specific irreversible inhibitor of the 20S proteasome that has been shown to block ansamycin depletion of HER2 protein (Fenteany et al., 1995; Mimnaugh et al., 1996). Treatment with lactacystin alone had no measurable effects on any of the proteins being studied (DNS). However, in the presence of lactacystin, 17-AAG still inhibited HER2 phosphorylation and caused decreased binding of HER3 to the p85 subunit of PI3 kinase and inhibition of Akt activation (Figure 3c). Additionally, 17-AAG induced reductions in cyclin D1 and D3 levels were not abrogated by lactacystin (Figure 3c, DNS). Thus, inhibition of HER2 activity by 17-AAG is coupled to but not dependent upon HER2 degradation.
17-AAG reduced HER2 expression, the association of HER3 with HER2, and HER3 phosphorylation and association with active PI3 kinase at concentrations and times correlated with loss of Akt activity. To test whether 17-AAG inhibited Akt activation by preventing the recruitment of PI3 kinase to the membrane by HER3, a p110 catalytic subunit of PI3 kinase engineered to bind the membrane was introduced into cells. In this protein the C-terminal of p110 is fused to the CAAX box (CVLS) of H-Ras, allowing farnesylation of p110 and its constitutive binding to the membrane in the absence of docking to receptor (Wennstrom and Downward, 1999).
Expression of p110-CAAX in SKBr-3 cells did not alter induction of degradation of HER2 by 17-AAG. In transfected cells, Akt activity was elevated fourfold and D-cyclin expression was increased threefold (DNS)(Muise-Helmericks et al., 1998). However, 17-AAG inhibited neither Akt phosphorylation nor kinase activity in the transfectants (Figure 4a). Moreover, in these cells, 17-AAG did not cause dephosphorylation of the Akt substrates 4E-BP1 and GSK-3 (Figure 2a). LY294002, a direct inhibitor of PI3 kinase, did inhibit Akt kinase in control and transfected cells (Figure 4b). Thus, inhibition of Akt activity by 17-AAG is a result of loss of PI3 kinase docking to HER3.
Ansamycins cause an RB-dependent G1 arrest associated with decreased D-cyclin expression (Srethapakdi et al., 2000). The sensitivity of breast cancer cells with high HER2 to 17-AAG is correlated with a rapid decrease in cyclin D1 and D3 expression (P Munster, unpublished data and Figure 2b). 17-AAG and LY294002 both inhibited cyclin D1 and D3 expression in SKBr-3 cells (Figure 2b). We were unsuccessful at detecting cyclin D2 in these cells. Additionally, 17-AAG inhibited cdk4 expression (DNS). The effect of 17-AAG on D-cyclins, but not cdk4, was abrogated in the p110-CAAX transfectants (Figure 2b). However, LY294002 potently inhibited Akt activity and D-cyclin expression in these cells (Figures 2b and and4b).4b). Thus, cyclin D1 and D3 expression is dependent on Akt activation by PI3 kinase in SKBr-3 cells. 17-AAG inhibited D-cyclin expression by downregulating this pathway upstream of PI3 kinase.
The potent inhibition of Akt activation by 17-AAG suggested that it might be a useful therapeutic agent in breast cancers with high levels of HER2 expression. We sought to determine whether inhibition of this pathway could be achieved in vivo at non-toxic doses of the drug. Unlike SKBr-3, BT-474 cells are tumorigenic when injected into nude mice and therefore we chose this model to study the in vivo effects of 17-AAG. BT-474 breast cancer cells overexpress HER2 and responded to 17-AAG in tissue culture in a fashion similar to SKBr-3 (DNS).
In mice, the maximally tolerated dose (MTD) of 17-AAG given daily for 5 days ranged from 75 – 125 mg/kg. Doses exceeding the MTD were associated with weight loss, elevated liver transaminase levels, anaemia and death. Mice treated with 17-AAG 75 mg/kg × 5 consecutive days with a second cycle repeated 2 weeks later demonstrated no gross toxicity or progressive weight loss. At this dose level, treatment resulted in a dose-dependent inhibition of the growth of the tumor xenografts (Figure 5a, DNS). A maximum mean tumor regression of 58% was noted on day 25, the final day of cycle 2.
The effect of treatment on Akt activity was determined after a single dose of 50 mg/kg 17-AAG. Mice were sacrificed pretreatment and at various times after drug injection. HER2 expression fell 50% by 4 h after treatment and 90% after 10 h. Two hours after drug exposure, phosphorylated Akt was reduced by 90%. Levels of both HER2 and phosphorylated Akt remained depressed 24 h after drug administration. Under these conditions, there was no significant change in Akt or p85 expression nor was any toxicity noted (Figure 5b, DNS). In contrast, MCF-7 xenografts treated with a single dose of 17-AAG (50 mg/kg) demonstrated no comparable rapid loss of P-Akt (DNS). 17-AAG at doses tolerable to the host had anti-tumor activity and induced HER2 degradation and Akt inactivation in breast tumor xenografts that overexpress HER2.
Akt kinase plays an important role in the pleiotropic control of cell growth, integrating pathways that regulate proliferation, apoptosis and metabolism (Marte and Downward, 1997; Vanhaesebroeck and Alessi, 2000). Engagement of the PI3 kinase pathway activates Akt and is required for transformation by tyrosine kinase receptors (Bardelli et al., 1999; Penuel and Martin, 1999; Skorski et al., 1997). The PTEN tumor suppressor gene encodes a lipid phosphatase that dephosphorylates phosphatidyl inositol-3′ phosphates and inhibits Akt (Stambolic et al., 1998). Mutational inactivation of PTEN is a common event in human cancer and results in high levels of Akt activity (Li et al., 1997; Steck et al., 1997). Thus, activation of Akt is a potent oncogenic stimulus and often occurs in human cancers. Functional inhibitors of Akt might be expected to inhibit tumor cell growth and increase their sensitivity to stimuli that induce apoptosis (Page et al., 2000).
We showed here that the ansamycin antibiotic 17-AAG inhibits Akt function in tumor cells in a complex manner. Ansamycins cause the degradation of a subset of proteins that require Hsp90 for conformational maturation (Czar et al., 1997; Mimnaugh et al., 1996; Pratt, 1998; Schulte et al., 1996; Stancato et al., 1997; Webb et al., 2000; Whitesell and Cook, 1996). In this study, the drug caused a reduction in Akt protein levels after 12 – 24 h of treatment. This was accompanied by a parallel decline in Akt activity. Akt may be a direct target of ansamycins. Hsp90 has recently been reported to associate with Akt and regulate its activity (Sato et al., 2000). Our preliminary data suggests that Akt associates with Hsp90 and 17-AAG results in the proteasomal degradation of Akt.
In most of the cells that were tested, ansamycins depressed cellular Akt activity by reducing its expression. However, in breast cancer cells that express high levels of HER2, 17-AAG also caused rapid inhibition of Akt kinase activity. Inhibition was secondary to down-regulation of HER2-dependent signaling. Ansamycins induce the degradation of mature membrane bound HER2 by an Hsp90-dependent process, but the underlying mechanism of this is not completely defined (Xu et al., 2000). In these cells, active HER2 forms heterodimers with HER3, a kinase defective protein that is phosphorylated by HER2. Tyrosine phosphorylated HER3 binds to PI3 kinase and brings it to the membrane. Degradation of HER2 in cells exposed to 17-AAG led to HER3 dephosphorylation, loss of its association with PI3 kinase, and a rapid decline in Akt activity. As a consequence, the phosphorylation of Akt substrates declined, cyclin D expression fell and the cells were sensitized to agents that induce apoptosis. We have shown that 17-AAG causes modest apoptosis and sensitizes cells to the apoptotic effect of taxanes (Munster et al., 2001). Introduction into cells of a p110 catalytic subunit of PI3 kinase that does not require docking to a receptor in order to bind the membrane prevented these effects of 17-AAG (unpublished data).
Lactacystin is a specific irreversible inhibitor of the 20S proteasome (Fenteany et al., 1995). This inhibitor abrogated the effect of 17-AAG on HER2 protein expression but failed to prevent the loss of HER2 and Akt phosphorylation, and D-cyclin expression. In cells pretreated with lactacystin, 17-AAG treatment resulted in a loss of HER2 from the plasma membrane and an accumulation of HER2 within cytoplasmic vesicles (DNS). It is likely that HER2 loss following 17-AAG treatment involves its ubiquitination and targeting to the proteasome (Mimnaugh et al., 1996). These data suggest ubiquitinated HER2 is functionally inactive prior to proteasomal degradation.
These results have several important implications. Amplification and overexpression of the HER2 gene occurs in 30% of breast tumors and a significant number of other cancers (Slamon et al., 1987, 1989; Tal et al., 1988). Overexpression is associated with an aggressive clinical phenotype and an antibody directed against the extracellular domain of HER2 has anti-tumor activity in patients (Baselga et al., 1996; Pegram et al., 1998). Our data suggest that in breast cancer cells with elevated HER2 and HER3 expression, Akt kinase is active and required for efficient expression of cyclin D1 and D3. Thus, in these tumors HER2 may function both to accelerate G1 progression by deregulating D-cyclin expression and to suppress apoptosis via other Akt-dependent pathways.
Inhibition of Akt function by 17-AAG may be responsible for many of its biologic effects. Despite their spectrum of targets, the cellular effects of ansamycins are quite selective. They cause RB-dependent G1 arrest with subsequent apoptosis (Srethapakdi et al., 2000). The RB-dependence of the arrest suggests that ansamycins selectively downregulate pathways required for cyclin D-cdk activation. Hsp90 is involved in the stabilization of cdk4, a protein targeted by the ansamycins (Stepanova et al., 1996). Additionally, the drug causes loss in D-cyclin expression by downregulating a PI3 kinase, Akt dependent pathway (Muise-Helmericks et al., 1998). Akt regulates both the translation and stability of cyclin D-protein (Diehl et al., 1998; Muise-Helmericks et al., 1998). The work described here suggests that inhibition of signaling pathways that activate Akt together with direct effects on its expression may account for both the anti-proliferative and pro-apoptotic effects of ansamycins.
The anti-HER2 antibody Herceptin has anti-tumor activity in patients with breast cancer that is enhanced in combination with cytotoxic agents (Gilewski et al., 2000; Pegram et al., 1998, 1999). A drug that induces the potent degradation of HER2 together with a rapid loss in Akt activity could have significant therapeutic utility, but may be toxic in vivo. In this report, we show that 17-AAG caused downregulation of HER2 expression and Akt inactivation and had anti-tumor activity at doses that were tolerable to the animal. Furthermore, in ongoing phase 1 clinical trials, peak serum levels of 2 µm 17-AAG have been obtained in the absence of significant toxicity (H Scher, N Rosen, unpublished data). In tissue culture models, less than 10 nm 17-AAG was required for marked inhibition of Akt kinase in breast cancer cells that overexpress HER2. Although one cannot presume that serum drug levels reflect intratumoral levels, these data suggest that inhibiting Akt kinase in tumors by 17-AAG is feasible and thus represents a novel strategy for cancer treatment.
17-AAG (NSC 330507, NCI, Bethesda, Maryland, USA), LY294002 (Biomol, Plymouth Meeting, Pennsylvania, USA), and lactacystin (Sigma, St Louis, Missouri, USA) were dissolved in 100% DMSO. Lipids (Sigma) were stored in chloroform and sealed under nitrogen.
The human cancer lines MCF-7, MDA-MB-468 (MDA-468), SKBr-3, BT-474 (American Type Culture Collection, Manassas, Virginia, USA) were maintained in 1 : 1 mixture of DME:F12 supplemented with 2 mm glutamine, 50 units/ml penicillin, 50 units/ml streptomycin, and 10% heat inactivated fetal bovine serum (Gemini Bioproducts, Calabasa, California, USA) and incubated at 37°C in 5% CO2.
Polyclonal antibodies: Akt, P-Akt (Ser-473), P-4E-BP1 (Ser-65), P-GSK-3 (Ser-21/9), P-PDK1 (Ser-241) (Cell Signaling, Beverly, Massachusetts, USA); p85, p110α, PDK1, GSK-3 (Upstate Biotechnology, Lake Placid, New York, USA); Cyclin-D1 (m-20), 4E-BP1 (r-113), HER2 (c-18), HER3 (c- 17), P-HER2 (Santa Cruz Biotechnology, Santa Cruz, California, USA). Monoclonal antibodies: PY99 (Santa Cruz Biotechnology). HER3 (Ab-7) (Neomarkers, Fremont, California, USA) was used for immunoprecipitation.
Cells were exposed to 17-AAG or DMSO vehicle. Cells were lysed in NP-40 buffer (50 mm Tris, pH 7.5, 1% Nonidet P-40, 150 mm NaCl, 2.5 mm Na3VO4, 10mm phenylmethylsulfonyl fluoride, and 10 µm each leupeptin, aprotinin, and soybean trypsin inhibitor) and cleared by centrifugation. Protein concentration was determined by using BCA reagent (Pierce Chemical Co., Rockford, Illinois, USA). Immunoprecipitations were performed using Protein-G Sepharose (Amersham, Piscataway, New Jersey, USA). Samples were separated by 7 – 10% SDS – PAGE, transferred to nitrocellulose, immunoblotted and detected by chemiluminescence using the ECL detection reagents (Amersham).
Kinase activity was assayed using New England Biolabs Akt Kinase Kit. Akt was immunoprecipitated, washed twice with lysis buffer, then twice with kinase buffer (25 mm Tris pH 7.5, 5 mm beta-glycerolphosphate, 2 mm DTT, 0.1 mm Na3VO4, 10 mm MgCl2). Two hundred µm ATP and 1 µg substrate (paramyosin fused to a GSK-3 crosstide) were added and assays were performed at 30°C for 30 min. Reaction mixtures were separated by 10% SDS –PAGE and the P-GSK3 reaction product was detected by immunoblotting.
Cells were lysed in 137 mm NaCl, 20 mm Tris pH 7.5, 1 mm MgCl2, 10% v/v glycerol, 1% v/v Triton X, 10 mm phenylmethylsulfonyl fluoride, and 10 µm each leupeptin, aprotinin, and soybean trypsin inhibitor. HER3 immunoprecipitation complexes were washed three times with 1% Triton X-100 in PBS, twice with 0.5 m LiCl, 0.1 m Tris pH 7.5, and twice with 10 mm Tris pH 7.5, 100 mm NaCl, 1 mm EDTA. Complexes were incubated for 20 min at room temperature with 1 µm ATP, 5 µCi ATP (γP32), and a 0.5 µm/ml 1 : 1 lipid mix of phosphatidylinositol and phosphatidylserine in 10 mm HEPES pH 7.0, 1 mm EGTA. The reaction was quenched by 1 m HCl and lipids were extracted with 1 : 1 CHCl3 : CH3OH. The organic layer was separated by thin layer chromatography eluted with 50 : 15 : 35 1-propanol : methanol : glacial acetic acid and detected by autoradiography.
The activated PI3k construct was provided by J Downward. The carboxy-terminal farnesylation signal from H-Ras was fused to p110 (myc-tagged p110-CAAX in pSG5 vector) (Wennstrom and Downward, 1999). Two million cells were transfected with 2 µg of DNA and 10 µl Lipofectin reagent (Life Technologies, Rockville, Maryland, USA). Experiments were performed 24 h after transfection.
Six-week-old athymic BALB/c female mice (NCI-Frederick Cancer Center) were maintained in pressurized ventilated cages. Experiments were carried out under an IACUC approved protocol and institutional guidelines for the proper, humane use of animals in research were followed. Prior to tumor cell inoculation, 0.72 mg SR 17B-estradiol pellets (Innovative Research of America, Sarasota, Florida, USA) were placed subcutaneously into the right flank. 1 × 107 BT-474 cells were mixed 1 : 1 with Matrigel (Collaborative Research, Bedford, Massachusetts, USA) and injected subcutaneously. Mice were randomized to treatment or control groups and treated with 17-AAG (75 mg/kg) or the egg-phospholipid (EPL) vehicle alone in cycles of 5 consecutive days. Treatment cycles were repeated 2 weeks later. Mice were weighed and tumors were measured with vernier calipers. Tumor volumes were calculated with the formula: π/6 × larger diameter × (smaller diameter)2. To analyse cellular markers, mice with established tumors were treated with a single dose of 17-AAG 50 mg/kg i.p. Mice were sacrificed pre-treatment and 1, 2, 4, 10 and 24 h post-treatment. For immunoblotting, tumor tissue was homogenized in 2% SDS lysis buffer (pH 7.4).
We thank J Downward and S Wennstrom for providing the p110-CAAX construct. We thank M Moasser for his helpful discussions and technical assistance. This work was in part supported by the NCI Breast SPORE program grant P50CA68425, grant number CA0951 from the National Cancer Institute and the generous support of the Arlene Taub Foundation.
PubMed Central Canada is a service of the Canadian Institutes of Health Research (CIHR) working in partnership with the National Research Council's national science library in cooperation with the National Center for Biotechnology Information at the U.S. National Library of Medicine(NCBI/NLM). It includes content provided to the PubMed Central International archive by participating publishers.


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Color Option
3Shape's new RealColor™ Technology in the TRIOS® Color digital impression-taking solution facilitates the creation of scan images in the appearance of real teeth and gingiva. The natural looking colors provide an excellent scanning experience, and make it easy for dentists to distinguish between the different types of restorative materials (metals, enamel, composite, etc.), recognize bleeding areas, see color transitions on teeth, and easily identify margin lines with enhanced detail.
General benefits of digital impression taking:
LAB – Streamlined workflow
DENTIST - High quality clinical results
PATIENT – Better experience
Specifications for PodLaptops suitable for TRIOS™ pod, Color or Black & White Versions:
TRIOS scanner benefits and features
Scanning has never been easier. No need to hold the scanner at a specific distance or angle for focus. Dentists or assistants can even rest the scanner on the teeth for support as they scan.
TRIOS cart benefits and features
General benefits of digital impression taking


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Gallery Link: – Home > Television Productions > [2009-2011 & 2015-] General Hospital > Episode Stills > 2017 > May
Welcome to Lexi Ainsworth Source – your online resource for all things featuring, Lexi Ainsworth. You may know Lexi as Kristina Corinthos-Davis on the Soap Oprea General Hospital. Fans may also recognize Lexi from other projects such as A Girl Like Her, Death Clique and The Gray Man .
Our purpose of the site is simple – to deliver news, photos, career updates, and other information relevant to Lexi and her career to her dedicated fans. We hope you enjoy the site and visit often for the latest updates.
Maintained By: Ka
Opened: September 2015
Host: Flaunt Network
Contact: email
Lexi Ainsworth Source is in no way affiliated with Lexi Ainsworth, her management, friends, or family. This is a fansite made by fans for fans. All photos used on this site are copyright to their original owners. No copyright infringement is intended. If you need something removed from this site please do not hesitate to contact me.
Gallery Link: – Home > Television Productions > [2009-2011 & 2015-] General Hospital > Episode Stills > 2017 > May


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Kochi, Oct 1: The NIA special court on Tuesday found 13 accused, including alleged Lashkar operative T Nazeer, guilty in the case relating to recruitment of youths from Kerala for terror camps in Kashmir.
Five others were acquitted by Judge S Vijayakumar, who is likely to pronounce the sentence on October 4.
All the 18 accused were produced in the court.
The case relates to recruitment of men from Kerala to the camps in Kashmir for terror-related incidents in 2006.
The case was registered by police at Edakkad in Kannur district and later handed over to NIA which had filed the charge sheet in the case in February 2011.
Two accused in the case are absconding. All the 18 accused were produced in the court, where the security was very tight.


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JetBlue Airways (NASDAQ: JBLU), the leading carrier at Fort Lauderdale-Hollywood International Airport (FLL), will launch a new route to Pittsburgh International Airport (PIT) on October 29, 2014. The service will complement JetBlue's existing route from Pittsburgh to Boston Logan International Airport, and is one of five upcoming routes announced for Fort Lauderdale-Hollywood in 2014/15. To celebrate the new route, flights are now on sale starting at $79 one way (a) for travel between October 29 and December 17, 2014 on Tuesday, Wednesday and Saturday (blackout dates November 20 to December 1, 2014). Tickets must be purchased by April 15.
"Pittsburghers have asked for a nonstop, year-round connection to Florida. With the introduction of this service, customers will not only save time, but also save money as this is traditionally a high-fare route. Besides access to South Florida, this will also meet the great demand for travels onwards to the Caribbean and Latin America," said Robin Hayes, JetBlue's President.
"We are really excited to be adding another flight to the offerings at Pittsburgh International," said Allegheny County Executive Rich Fitzgerald. "This connection to Florida will benefit business and leisure travelers and gives our region one more option for their travel. We look forward to continuing to work with JetBlue to grow that service here in Pittsburgh."
JetBlue currently operates 26 nonstop routes out of Fort Lauderdale-Hollywood, with five more new routes already announced to begin in 2014/15. On May 1, JetBlue will add three new nonstop routes from Fort Lauderdale-Hollywood to Montego Bay (Jamaica), Port of Spain (Trinidad and Tobago) and Punta Cana (Dominican Republic). Next year, the airline also intends to launch a nonstop route to Albany, NY.
JetBlue's schedule between Pittsburgh (PIT) and Fort Lauderdale-Hollywood (FLL), effective October 29, 2014:
|PIT to FLL:
|FLL to PIT:
|Depart - Arrive
|Depart - Arrive
|07:15 a.m. - 10:00 a.m.
|6:55 p.m. - 9:31 p.m.
(a) Fare includes government taxes/fees and must be purchased by 4/15/14 (the earlier of 11:59 PM ET or local) for flights between Pittsburgh, PA (PIT) and Ft. Lauderdale, FL (FLL) on Tues., Weds. and Sat. between 10/29/14 and 12/17/14 (blackout dates 11/20/14 - 12/1/14). 21-day advance purchase required. Fare is subject to availability; may not be available on all days or all flights; may change without notice; must be purchased at time of reservation; and is one-way, nonstop, nonrefundable and nontransferable. Reservations made one week or more prior to a flight's scheduled departure may be canceled without penalty up to 24 hours after the reservation is made. Fare not available for purchase via Online Travel Agencies Orbitz, Travelocity, Expedia, Hotwire, CheapTickets, LowestFare or Priceline. First checked bag is free (weight and size limits and exceptions for itineraries including flights marked or operated by other airlines apply). Fare does not include fees for oversized/overweight/extra baggage or other fees for products/services sold separately. To view baggage fees and other optional services and fees, click here. $25 fee per person applies to fares purchased by phone or at an airport or ticket office. Cancellations/changes must be made prior to scheduled departure (otherwise all money for fare is forfeited); $150 change/cancel fee per person will apply, and for changes, there may be a fare adjustment. Cancellations receive JetBlue travel credit, valid for one year. Proper documentation required for boarding. Other restrictions apply.
Logos, product and company names mentioned are the property of their respective owners.


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When a prisoner is shot to death in the exercise yard of a Saskatchewan penitentiary, Joanne Kilbourn finds herself haunted by a part of her past she wished had never happened. The dead prisoner is Kevin Tarpley, the man who six years earlier had brutally killed her politician husband, Ian, in a seemingly senseless act alongside the TransCanada Highway.
The haunting takes on a more menacing cast several days later when Tarpley's sinister wife, Maureen, is discovered dead in a snow-swept Regina parking lot. A brightly colored scarf is found wound tightly around her neck, a scarf that belongs to none other than Joanne Kilbourn. Soon this single mother, author, university professor, and TV-show panelist is deemed the number-one suspect in Maureen Tarpley's demise.
Joanne knows there has to be a connection between these two murders. But what is it? A cryptic letter sent to Joanne by Kevin Tarpley just days before his death intimates that Ian Kilbourn's killing may not have been as senseless as first assumed. In fact there are hints that some of Ian's political colleagues may have been involved. But how deeply and in what way?
Then there's the faded photograph of a pretty young woman and her baby that Joanne finds tucked in the wallet of her dead husband. Does it offer any clue to Ian's murder or to the deaths of the Tarpleys? Warily, Joanne Kilbourn is forced to follow a tangled trail deep into a heartbreaking past she never knew existed.
A Colder Kind of Death is the fourth novel featuring Gail Bowen's reluctant sleuth, Joanne Kilbourn. With its deft mix of wry humor and mayhem, closely observed family scenes and gripping suspense, warm characterization and betrayal, it confirms Gail Bowen's stature as one of the greats of mystery fiction.
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NTA and the Macro Economy. Using macro controls when constructing National Transfer Accounts. I. Introduction. Goal of session: To construct aggregate controls for NTA based on UN System of National Accounts (SNA)
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Using macro controls when constructing National Transfer Accounts
Private age reallocations
Lifecycle account
Public age reallocations
Calculated from components
Calculated from SNA with adjustments
Sums of components
Calculated from SNA with adjustments
Public transfer inflows + transfers from ROW
Gap between taxes and transfer outflows
Sum of components
Not available from SNA
Sum of components
Estimated from SNA
Sum of components
In NTA all flows are from the perspective of age groups (or the individuals that make up those age groups)
Consumption & saving of age group x
Disposable income of age group x
Labor income
Capital income
Property income
Net transfers
Secondary income
Use of income
Primary income
Note: Methods documented on LC and RA sheet, Macro control based on UNSNA 2008.training version.xlsx
System of National Accounts
National Transfer Accounts
Note that primary income is less in NTA than in SNA to the extent that SNA primary income includes taxes on consumption.
Adjustments to convert SNA components into NTA components
Example: public transfer inflows Subsidies
→from public consumption
Example: macro controls for consumption Subsidies
Example: macro controls for labor income Subsidies
x 2/3


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Miguel from Riverbank writes,
How do I get rid of ants in rock bed next to house? I've tried Talstar P and got rid of roaches not ants....
Regular small ants spray not penetrating under rocks
If you are able to move the rock bed to access the soil underneath, that will provide you the best results. Talstar P works as a repellent but does not work to kill off the colony. Using Termidor SC as a perimeter spray 1ft up and 1ft out from the structure will provide you with 6 month ant control. But with out being able to access the dirt area under the rocks, you might not get full results.
Using Maxforce Complete Granular Bait sprinkling as a bad around the structure or in bait plate stations will help as well.
Maxforce Complete Brand Granular Bait may be sprinkled around structures and/or applied to refillable/serviceable bait stations as outlined below. Sprinkle this product evenly in a 1-2 foot wide band adjacent to the structure at a rate of 0.5 oz (one tablespoon) of bait per 25 linear feet. NOTE: Around structures the total application should not exceed 4-8 oz per 200-400 linear feet (or 0.5 oz per 25 linear feet). Be sure to treat areas such as porches, patios, driveways, sidewalks, flower gardens, landscape timbers and around trees, wood piles, air conditioning units and garbage receptacles.
Answer last updated on: 03/24/2015
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Use our partner links below to find fun, exciting, productive activities for East Aurora School District children and parenting information for adults!
The Boys & Girls Club of East Aurora provides positive afterschool activities for kids, ages 7-18 Athletics - dodgeball, floor hockey, basketball, etc.; Homework Help & Tutoring; Arts & Crafts - pottery, ceramics, baking & cooking; Social Recreation games & challenges; Technology - Computer Lab, Tech education programs, graphic design; Guitar Hero & Garage Band; Nutrition; Prevention "Smart" Programs; and so much more!
Sports, crafts, theater and more!
Girl Scouts is dedicated solely to girls, with an accepting and nurturing environment where girls build character and skills for success in the real world.
The mission of the Boy Scouts of America is to prepare young people to make ethical and moral choices over their lifetimes by instilling in them the values of the Scout Oath and Law.
Cub Scout Pack 514
The museum has over 5,000 square feet filled with hands-on exhibits and exploration. Its program schedule includes on-going activity days and celebrations for the general public. There are specialty programs at the museum for students in Kindergarten through Sixth Grade, scouts and preschool students.
Your group can be added to this list if it is a non-profit group that serves Town of Aurora children 18 and younger. Contact Lori Gervasi for more information.
Use our partner links below to find fun, exciting, productive activities for East Aurora School District children and parenting information for adults!


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20th CEO Survey
Over the past two decades Entertainment and media (E&M) CEOs have witnessed tremendous transformation – primarily driven by globalisation and technological evolution. Our 20th Annual Global CEO Survey reveals that their concerns centre on changing consumer behaviour, the availability of key skills, and volatile energy costs. Despite these concerns E&M CEOs are more optimistic about economic and business growth over the next year. To respond to changing consumers' needs, E&M CEOs need to understand how economic, technological, and human capital forces are impacting the user experience and driving change within the entertainment and media industry.
This year's survey reflects increased optimism among E&M CEOs about the prospects for economic growth. Thirty-five percent of E&M CEOs believe the global economy will improve over the next 12 months, which is up from 22% last year and higher than the global CEO population. In addition, E&M CEOs are also more optimistic about their own company's growth prospects. Thirty-three percent of E&M CEOs (vs. 26% last year) are "very confident" about their company's business growth prospects in the next year. Key areas of growth within the entertainment and media industry, include the growth of streaming and video-on-demand (VoD) services, improvements in content discovery, and the rise of mobile video.
E&M CEOs understand the near-term benefits of business transformation, but they also must consider the long-term impact to their business. E&M leaders have grown far more concerned with changing consumer behaviour – 81% are concerned compared with 76% last year. For instance, emerging technology (virtual reality, wearable tech, and artificial intelligence digital assistants) is impacting how content is created and distributed. In other research (see our global entertainment & media outlook 2017-2021), we see spending on internet advertising has maintained its momentum, as consumer demand for internet access continues to grow globally, and high-speed mobile connections become increasingly available and affordable in developing markets. The availability of key skills and volatile energy costs are the second and third top threats among E&M CEOs.
"The world is changing as innovations for human life and knowledge generation are accelerating. Many intractable problems facing people are now being resolved. What might have taken ten years in the past, now only takes one year. We can feel the pace of change accelerating, although growth in our lifetime will be relatively slow. If our lifespan increases from 70 years to 100 years, we will feel the changes of the world more because we really do not know what the world will be like in 2030."
To capitalise on new opportunities, organisations must have the right capabilities in place. E&M CEOs see 'digital and technological capabilities' and 'innovation' as their top two areas of focus. Additionally, many E&M CEOs believe that technology will completely reshape competition in their industry over the next five years: 56% of E&M CEOs vs. 23% of all CEOs in the study. Technological advancements are requiring companies to rethink transactions, business models, and capabilities. By balancing agile and lean practices in innovation, companies can take steps forward and expand their media capabilities. In a strategy+business article, 'You're a Media Company. Now What?', PwC's John Sviokla and Deborah Bothun explain that "the battle for the consumer's attention has become brutal, and requires new strategies and capabilities. Companies across many sectors are reaching the same conclusion: We all have to be in the media business."
Seventy-eight percent of the E&M executives say that they are concerned about the availability of talent. E&M CEOs ranked 'Leadership' as the third most important skill for the E&M industry and view it as the hardest skill to source. 'Creativity' is the second-most difficult skill to find. As technology, data, and analytics become more powerful, expanding the use of automation, executives will need to think through which human tasks are being assisted or augmented by emerging technologies – and which ones are being replaced. Forty percent of the E&M executives say that, over the next five years, headcount will decrease to a large extent as a result of automation and other technologies. That number compares to just 25% for all CEOs in the study. The result is conundrum for E&M CEOs; the hardest skills to find are those that can't be performed by machines and yet the E&M industry is expected to lose more jobs to technology than most other sectors.
Chris Vollmer
Global advisory leader, Entertainment and media
Tel: +1 (212) 551 6794


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Free Kindle eBook: Gardening For Indoors And Outdoors: Collection Of A Handful
Today's Free Kindle eBook: Gardening For Indoors And Outdoors: Collection Of A Handful Of Gardening Tips, Tricks, Strategies And Idea's To Garden Indoors And Outdoors
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San Diego Chargers running back LaDainian Tomlinson completed pregame warm-ups, running through a variety of agility tests and acceleration drills. He started against the Indianapolis Colts on Saturday night despite a groin injury.
Chargers tight end Antonio Gates did not work out in the pregame but will play. According to Norv Turner, the team didnt' feel it was necessary to test Gates, who also played.
Tomlinson told ESPN's Ed Werder as he left the field after warm-ups the groin injury is painful but he feels like he can change direction. The question, Tomlinson said, is how how long he will last if the pain intensifies.
Tomlinson said he took pain medication, not an injection.


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The zombies are rebelling - try to stop them from escaping from the canyon prison and..
Zombie Canyon82% Zombie Canyon
You're a member of a very special unit: kill all the freaky creatures and save your life..
Army Of The Dead84% Army Of The Dead
The government have set up a Zombie defence tower in the middle of nowhere for seemingly no reason. Can you guys guess what happens next?
Try this experince with different content strung across different TV stations, and of course, plenty of fun blowing up you know what!
Arrow Keys / W and D to aim. Up / W to shoot. Mouse controls the TV stations.
Welcome to Flonga Games!
All the games on our site are FREE to play and we launch new games every day.
You can play thousands of free online games including action, life, puzzle, skill and sports games. Also there are a lot of interesting tags you can browse like tower defense games, room escape games or cooking games.
Flonga Homepage | RSS: New Games | Follow Us On Twitter | Top of the page


text: "I agree with the metaphysics of technical analysis that the fundamentals are discounted. You don't get any profits from fundamental analysis; you get profit from buying and selling. So why stick with the appearance when you can go right to the reality of price and analyze it better?" --Richard Dennis


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|86 m²
|Property type
|Minimum Stay
|30 nights
Furnished condominium available as a monthly vacation/seasonal rental, this light a bright second floor condo is a charming and quiet home to enjoy time in the North County San Diego coastal region of Encinitas. This property is a ONE MONTH MINIMUM rental. Nicely appointed, comfortable bedding, and well equipped, this unit has everything you need in a furnished monthly rental. The unit is West facing providing cool ocean breezes and a calming view of the tropical community pool and outdoor BBQ area.
Stairs from the lower level entrance and garage go up to main level living area with plush carpeting and wood floors throughout, two master bedroom suites with large closets, two master bathrooms with travertine tile floors. Nicely appointed clean kitchen with modern high-efficiency appliances. Charming living room with hard wood flooring and gas fireplace with tile facing. Family entertainment area has wide screen TV.
This property is close in proximity to Carlsbad State Beach, shops/restaurants/night life, LEGOLAND, and La Costa Golf Resort & Spa. Beautifully appointed and decorated, this home features 2 large bedrooms, 2 upgraded bathrooms with granite and tile throughout, full stocked and equipped custom remodeled kitchen, dining table for six, gas fireplace and cozy, inviting furniture. The property is ideal for a small family or two couples looking for a vacation getaway in North County San Diego.
The property has easy access to Interstate 5, Encinitas and Leucadia Blvds, and other San Diego transportation corridors. Grocery, pharmacy, nail salon, and churches are all within close proximity. Trips to Encinitas beaches, area golf courses unspoiled Cardiff by the Sea and Solana Beach, Del Mar Race track and County Fairgrounds or stunning Torrey Pines State Reserve and Torrey Pines Golf Course are a short drive away. It's also an easy day trip to other San Diego favorites such as Legoland, Sea World, historic Old Towne, the San Diego Zoo or Safari Park, Petco Park and the Downtown Gaslamp District.
Unit Amenities/Features:
- Large living/family room area – wall-to-wall carpeting
- Inviting gas fireplace
- Fully equipped kitchen with nice cabinets, clean counter tops, modern appliances
- Stove/range, microwave, dishwasher, refrigerator, coffee maker
- Garage and guest parking
- Common pool and outdoor BBQ area
Damage Protection Insurance is a required item charged at a flat $99 for $5,000 insurance for accidental damages which occur during your stay. For questions regarding Damage Protection Insurance and Security Deposits as well as to receive a rental reservation quote please contact our North County Property Group office to speak with a vacation reservation specialist. Reservation payment options include all major credit cards: MC, Visa, Discover, AMEX (3% transaction charge applies for credit cards payments).
Listing information deemed reliable but not guaranteed - agent, broker, and renter should confirm all property details and specifications before entering rental agreement.


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A private investigator who was previously jailed for his role in phone hacking at Rupert Murdoch's News of the World was bailed Wednesday after police probing the scandal detained him earlier in the day.
Police said a 41-year-old man had been arrested at 0700 GMT on suspicion of phone hacking and perverting the course of justice, and the BBC and the partly Murdoch-owned Sky News identified him as Glenn Mulcaire.
The arrest is the 18th made by officers working on Operation Weeting, the investigation set up in January into the illegal hacking of mobile phone voicemails at the paper, which was closed down in July.
"On 7 December 2011 officers from Operation Weeting arrested a man in connection with phone hacking and perverting the course of justice," London's Metropolitan Police said in a statement.
"The man was taken into custody at a south London police station and this evening released on bail to a date in late March, pending further investigation.
"It would be inappropriate to discuss any further details at this time," the statement added.
A Scotland Yard spokesman refused to confirm the reports that the man was Mulcaire when contacted by AFP.
Mulcaire's London-based lawyers also declined to comment.
Mulcaire, a former footballer turned private detective, and the News of the World's former royal editor Clive Goodman were jailed for six months in 2007 for hacking the voicemails of aides of Britain's royal family.
Goodman was re-arrested in July.
Rebekah Brooks, a former top executive in Rupert Murdoch's newspaper empire, and Andy Coulson, a former News of the World editor and Prime Minister David Cameron's former media chief, are among those previously arrested.
The Murdoch-owned News of the World was closed in July amid a storm of phone-hacking allegations, including that a private investigator had hacked the voicemail of a murdered teenage girl, Milly Dowler.
Last month Mulcaire denied claims made at a press ethics inquiry set up by the government in the wake of the scandal that he had deleted some of Dowler's voicemails, giving her parents false hope that she was alive.
Separately on Wednesday, lawyers working for News Corporation revealed that lawmaker Tom Watson, a long-time Murdoch critic, had been placed under surveillance in 2009.
Legal firm Linklaters told the Commons Culture, Media and Sport Committee that it had arranged for private investigator Derek Webb to follow Watson for five days.
Also Wednesday, Coulson launched a legal battle at the High Court in London against his former employer after it stopped paying his legal fees.
Coulson is suing a subsidiary of News International, the British newspaper wing of Murdoch's US-based News Corporation empire, over a clause in his severance agreement with the firm when he quit the News of the World in 2007.
His lawyer James Laddie asked for a declaration that Coulson's ex-employer "must pay the professional costs and expenses properly incurred... in defending allegations of criminal conduct" during his editorship.
"I should make it clear at this stage that the claimant denies any allegations of wrongdoing," Laddie said.
Coulson was not in court for the hearing.
After quitting the News of the World in 2007 following the jailing of Mulcaire and Goodman, Coulson went on to become Cameron's communications director.
But he resigned that post in January after he came under pressure over the phone-hacking scandal.
Mulcaire also launched legal action against Murdoch's empire in August after it stopped paying his legal costs.


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SEPA in disagreement over radioactive scale on Aberdeen beach
The Scottish Environment Protection Agency is stuck in the middle of a row over the level of risk posed by radioactive material washing up on a beach in Aberdeen.
Sorry you do not have access to this article. Please contact Customer Support at
or call 020 8267 8120


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Matters of the heart are not precisely a stroll in the greenhouse. Take for example how a brief smash may transform out into an all out relationship, or maybe you're so stricken by the person that you don't even know whether its affection or simply the desire taking.
On the off chance that feelings have not generally been your strong point, here's something to bail you out — a clever correlation diagram of like, affection, desire and even fixation.Next-Page>> 2


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Get a Free Move or Rebate when you lease
From Galveston Road and Emmett F Lowry Expressway, Texas City, Texas, drive southwest on Emmett F Lowry Expressway toward Galveston Road. Make the first left turn onto Texas-3 S/Galveston RoadContinue to follow Texas-3 S. Make a left turn onto Farm to Market 1765 E/Texas AveContinue to follow Farm to Market 1765 E. Make a right turn onto Texas-146 S. Take the I-45 S ramp to your left to Galveston. Continue on the ramp and merge onto I-45 S. Take exit 1A to merge onto Texas-342 Spur S/Broadway Street toward 61st St/W Beach. Make a right turn onto 61st Street (signs for Texas 342 Spur). Make a right turn onto Farm to Market 3005. Antigua Apartments will be on the right.
For a lovely apartment home with a gorgeous view of the ocean and beachfront of Galveston, Antigua Apartments offer stunning views. Close to Schreiber and Jones Parks and the Schlitterbahn Galveston Island Waterpark, there are plenty of activities and entertainment in and out of the water. Residents can enjoy colorful sunrises and sunsets from their front door or out on the beach.Palm trees line these cottage look oceanfront apartments and red tile roofs add to the tropical feel. All apartment homes feature at least one full bath and air conditioning for warm nights. Walk in closets afford plenty of storage space. Kitchens are equipped with a range top stove, refrigerator, double sink and dishwasher. Large pantries provide ample storage for dining pleasures.Antigua Apartments are a pet friendly community. Ample parking is provided for residents and guests. Some units include a patio or balcony for viewing the ocean right at home.


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Chelsea defender Alex looks set to miss 6-8 weeks because he needs to undergo knee surgery. The Brazilian defender has withdrawn from the Brazil squad to play Argentina this week.
The defender has missed Chelsea's last two games in the Premier League against Fulham and Sunderland. This news is heart breaking for Chelsea manager Carlo Ancelotti following captain John Terry's admission that he could be out for 'months' with a nerve complaint in his leg.
A Chelsea spokesman said on Tuesday:
John reported for training this morning. He met with club doctors and medical team and discussed plans to continue seeing various specialists to try to find a solution to the nerve problems he has been experiencing in his right leg.


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Every true fan of One Direction will want these collectible plush bears and pillow. Each member of the band has his own 9" Plush Bear with his photo on the bear's hoodie and his facsimile signature embroidered on its paw. The comfy Pillow (13-1/2" x 14") features a photo-real image of all the boys in the band. Polyester. Imported.
- Show how big a fan you are!
- Collect all the bears
- Details:
- Bear, 9" tall
- Pillow, 13-1/2" x 14"
- Polyester
Quick View
$2.65 - $14.95
$2.65 - $14.95 One Direction Plush Bears or Pillow


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Models For Knob Hotplate 550
Knob Hotplate 550 by Indesit
£18.31 Discontinued
Normally £18.73
Email me when back in stock - we'll try to re-stock quickly!
The product Knob Hotplate 550 is suitable for the models listed below.
View full product details for Knob Hotplate 550.
Search our range of models by entering your model number to perform a search.


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Monkey Tower Defense
iBall Andi 4.5P Glitter smartphone was launched in April 2014. The phone comes with a 4.50-inch touchscreen display with a resolution of 480 pixels by 854 pixels. iBall Andi 4.5P Glitter price in India starts from Rs. 3,999.
The iBall Andi 4.5P Glitter is powered by 1.3GHz quad-core it comes with 512MB of RAM. The phone packs 4GB of internal storage that can be expanded up to 32GB via a microSD card. As far as the cameras are concerned, the iBall Andi 4.5P Glitter packs a 8-megapixel primary camera on the rear
The iBall Andi 4.5P Glitter runs Android 4.2 and is powered by a 1450mAh removable battery.
The iBall Andi 4.5P Glitter is a dual SIM (GSM and GSM) smartphone that accepts Regular and Regular. Connectivity options include Wi-Fi, GPS, Bluetooth, FM and 3G. Sensors on the phone include Proximity sensor and Accelerometer.
How to download Monkey Tower Defense form iBall Andi 4.5P Glitter?
- Check the Android version to verify compatibility of Monkey Tower Defense with iBall Andi 4.5P Glitter.
Find Android version: go to "Settings" - "About the phone" - "Android version". Make sure Monkey Tower Defense is compatible with iBall Andi 4.5P Glitter.
- Click the download button to download Monkey Tower Defense in iBall Andi 4.5P Glitter.
- Once the download and installation are complete, find Monkey Tower Defense in your home screen and tap the icon to open it.
Related apps to iBall Andi 4.5P Glitter
Throne RushDownload
Castle Clash: Anniversary PartyDownload
Papa's Pizzeria To Go!Download
METAL SLUG DEFENSEDownload
Bloons TD BattlesDownload
Fort ConquerDownload
Clash RoyaleDownload
Castle DefenseDownload
X-War: Clash of ZombiesDownload
Star Wars™: CommanderDownload
King's EmpireDownload
King of ThievesDownload
انتقام السلاطينDownload
Other supported phone models
Alcatel One Touch Pop 2 (4) Dual-SIM
Panasonic P77
Sony Xperia X Performance Dual
Spice Mi-402
LeEco Le Pro 3
Coolpad Note 3 Plus
Obi Hornbill S551
Intex Aqua Xtreme
Lava Iris Pro 20
Asus ZenFone 6
Samsung Galaxy Trend 3
Gionee Elife E6
Oppo R5
Celkon Millennium Ultra Q500
Huawei Ascend Mate 7
Vivo V5
Acer Liquid Z530
Xolo Q2500
Lenovo Vibe K5
Videocon Z55 Delite
Lyf Water 8
Philips S308
HTC Desire C
Swipe Elite 3
Micromax Canvas Xpress
Xiaomi Redmi 4X
ZTE Grand X 3
Archos 50 Oxygen +
Karbonn A27 Retina
Datawind Pocket Surfer 3G4
Blu Studio Energy 2
Motorola Moto G4 Plus
Maxx Mobile GenxDroid7 AX356
Wickedleak Wammy Titan 3 Octa
Adcom KitKat A35
Idea Ultra+
Zen Admire Thrill
InFocus M2
BlackBerry DTEK60
MTS Mtag 3.1
iBerry Auxus Handy H01
Meizu m3s
Nokia E1
Fly F51
Zopo Color F1
Yu Yureka S
Ringing Bells Elegance


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August 3, 2001 – Stacy Peralta's "Dogtown and Z-Boys," the winner of theAudience Award and the Director Award at the 2001 Sundance Film Festival,has been accepted to the Toronto International Film Festival. The film waswritten by Stacy Peralta and Craig Stecyk, produced by Agi Orsi andexecutive produced by Jay Wilson of Vans. It was narrated by Sean Penn.
"Dogtown and Z-Boys" will be released in April, 2002 by Sony PicturesClassics.
The high-flying "vert" style of skateboarding is such a defining element ofyouth culture, it's hard to believe it wasn't invented by a skateboardmanufacturer. In fact it was invented on the streets of Dogtown, a sectionof Santa Monica and Venice "where the debris meets the sea." In the early1970s, this rundown urban beach neighborhood spawned the Zephyr SkatingTeam. The Z-Boys took their clunky skateboards onto asphalt-banked schoolplaygrounds and empty swimming pools and learned to "carve" thesethree-dimensional terrains in new ways, instinctively gravitating to afluid, surfing-inspired style that was both stylish and improvisational.The Z-Boys caught the mainstream skating world off guard at the Del MarNationals in 1975, where they made their first splash. Within a year, theaggressive Dogtown style came to dominate the sport, and its young masters,Jay Adams, Tony Alva and Stacy Peralta, became international teenagesuperstars. "Dogtown and Z-Boys" is the story of a group of gifted kids whoinadvertently inspired an American pop culture phenomenon.
Former Z-boy and Director Stacy Peralta combines interviews with theoriginal Zephyr team members: Jay Adams, Tony Alva, Bob Biniak, PaulConstantineau, Shogo Kubo, Jim Muir, Peggy Oki, Stacy Peralta, Nathan Pratt,Wentzle Ruml and Allen Sarlo, with the stunning photography of Stecyk andGlen E. Friedman.
Stacy Peralta (Director, Co-Writer) is an original Z-Boy and is consideredone of the founding fathers of modern skateboarding. At nineteen, Peraltawalked away from his skating career and formed the skate company PowellPeralta. With the help of trend-setting graphic artists Craig Stecyk andVernon Courtland Johnson, Powell Peralta became an industry leader in justfive years. Peralta and his company discovered Tony Hawk. They sponsoredhim for eleven years as the founder and coach of Powell Peralta's BonesBrigade skateboard team. In 1984, Peralta and creative partner Craig Stecykproduced their first skateboard film, "The Bones Brigade Video Show,"launching a skate-video revolution that shifted the balance of power in thefield away from the traditional magazines and the corporate organizers ofcompetitive events. Many young skaters now routinely bypass competitionaltogether, choosing video instead.
Peralta has appeared in several skating films, including "Freewheelin'" in1976. He served as a second unit director on the films "Police Academy 4,""Gleaming the Cube" and "Thrashin.'" As a result of his video work with theBones Brigade, Peralta worked on Steven Spielberg's "Hook" (1990) as a scenechoreographer and skateboard consultant. After leaving Powell Peralta in1991, he began directing and producing television specials, pilots andseries. He recently directed the interview series "Influences" for Bravo.


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Tuesday, December 3, 2013 - 9:38am
According to Jeff Dickerson of ESPNChicago.com, the Browns signed QB Caleb Hanie to fill out the depth chart. The former Bears and Broncos backup has been out of the league since he was cut by the Ravens this summer.
Fantasy Impact:
With Jason Campbell and Brandon Weeden suffering concussions, the Browns may have to turn to Alex Tanney, so Hanie will help to fill the roster and provide a backup. The team is hoping at least Campbell will be ready to go for Week 14.
Filed Under: 2013, W14


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The McDonnell corruption trial, now in its third week, is an enormously sad and tawdry affair bringing shame on the defendants and the prosecution's key witness, businessman Jonnie R. Williams Sr.
Yet there are heroes — state employees. A number of them have testified over the past week that they sensed that something stunk with the way Williams, who has no formal science training, relentlessly pushed his questionable product and maneuvered to get the state's prestigious universities to put their imprimatur on it so it could move from being a low-margin neutraceutical to a real and profitable pharmaceutical.
"Perhaps the only gratifying aspect of the trial last week was the extraordinary professionalism of the Virginia bureaucracy," Richmond political analyst Bob Holsworth told the Richmond Times-Dispatch.
He's spot on. One reads so many attacks on government workers among more conservative writers who see public workers as slow-minded except when it comes to tying business up with regulations — the theory goes. Private workers build wealth and create products. Public workers live off the taxpayer's dime and should be fired in droves, one theory goes.
[Continue reading Peter Galuszka's post at Bacon's Rebellion.]
Peter Galuszka blogs at Bacon's Rebellion. The Local Blog Network is a group of bloggers from around the D.C. region who have agreed to make regular contributions to All Opinions Are Local.


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Subtle styling, softer suspension and more affordable than ever - the GXP is an HSV with a difference, although would-be owners will be glad that the V8 performance is identical to most of the range.
The GXP uses parts from other HSV models but aims to incrementally grow sales and attract new buyers to the brand known for its V8 performance.
With a name inspired by the same car sold as a Pontiac in the United States, HSV has created a limited edition car that undercuts the ClubSport R8 by about $10,000 and makes it the most affordable V8 from the muscle car brand in almost a decade.
And while HSV says the combination of more restrained styling and more affordable price will appeal to a different buyer to the rest of the HSV line-up (including the volume-selling ClubSport R8, Maloo R8 ute, luxury Senator and flagship GTS), buyers will be glad to learn that the core of the car is unchanged.
The 6.2-litre V8 still delivers 317kW and 550Nm and can accelerate the large sedan to 100km/h in a little over five seconds.
With four exhausts and a raucous sound and feel, the HSV ClubSport GXP delivers the essence of any other HSV.
The V8 rumble is always in your ear, even at low revs, acting as a constant reminder that the GXP is something special.
The HSV GXP has no launch control system, as with the ClubSport R8, although in everyday driving it's a moot point for those looking to hold on to their licence.
The HSV GXP will still jump from a standstill with amazing ease, with the V8 roaring boldy in the foreground.
A small beep from the gear change warning helps maximise performance with gear changes.
The six-speed manual (a six-speed auto costs another $2000) has a chunky feel that's in some ways complementary to the muscular feel of the V8.
Steering is responsive and decently weighted, those as with all current Commodores the windscreen pillars cut into through-corner vision.
While the rear tyres are smaller, our brief drive demonstrated the HSV GXP still has excellent cornering grip, with electronic stability control on hand to help control a skid.
And while HSV has stuck with the softer suspension chosen for the GXP sold in the US, the HSV GXP is still firm in its response to bumps and lumps, albeit with more compliance that removes the sharper edge of the ClubSport and GTS, the latter with adjustable shock absorbers that HSV calls Magnetic Ride Control.
Inside, the GXP is identical to the ClubSport R8 or Maloo R8 ute, although neither can be had with leather seats. HSV decided to simplify the model range and encourage those looking for leather to splash out more for the ClubSportR8 or Maloo R8.
While a colour screen, dual-zone climate control air-conditioning and the trio of gauges mounted on top of the dash help liven the otherwise plasticky dash, there's still plenty of Commodore in the overall look and feel.
The cloth seats look classy, though, and do a decent job of keeping you located as the road gets twisty.
As with all Commodores, space is generous, with good rear leg room and a large boot concealing a tyre repair kit and inflator (a temporary spare tyre costs extra).


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View Single Post
September 4th, 2013, 05:07 PM
Super Mommy
Join Date: May 2013
Location: Texas
Posts: 626
I sent u an email not sure if u got it cause it wouldn't let me pm u on here. But omg. I can't believe they could actually tell u to do that. That breaks my heart. The ladies are right only u can make this choice. But you are already feeling strongly that u don't want to terminate an are depressed im afraid it will be 10 times worse if u do go through with it. I'm sorry if that's out of line to say but omg this is a life. I'm sorry. I personally know a lady that for yrs tried to have a baby an was finally told by her dr that she could never have a baby. Then a 19yr old girl that was date raped and got pregnant could not go through with terminating gave her the baby. That baby is sooooo spoiled an her birth mom keeps in contact with my friend to find out how Kayla is an also sends her things. So please consider giving the baby to a woman like my friend that longs sooooo much for a baby before u consider terminating, I'm sooooo sorry if anything I say offends u but I feel I have to give u my opinion. I had my son at 16 so I know how scary it can be. I had to get on food stamps and Medicaid, but I did it. Please talk to any of us on here if you need to an as much as u need to. Don't be afraid to tell us anything. That's what we are here for to support each other in the good an bad times. I'm praying sooooo hard for u
Make a pregnancy ticker
DS-Jesus (a.k.a J)-14yrs
View Public Profile
Find all posts by jjustice12


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Get ready for a great coin auction, all out of 1 estate, with gold coins, rolls of silver coins, commemorative coin sets, foreign coins, stamp collection, mint & proof sets, and much more pics and catalog coming soon!
We are on Colonel Glenn Rd. close to Western Hills Ave., we are connected to Oxford Graphics and next door to Dollar General store.... watch for banner and sign close to road.Get Directions
Cash & Visa, M/C, & Discover cc accepted


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This product is no longer available.
You can try these similar gifts instead.
Wine and Red Wine Snaps Gift Basket
Any wine enthusiast will enjoy this thoughtful gift. It includes a bottle of red wine, you choose, paired with delightful snacks including Red Wine Snaps, a delicious biscuit that has a flavor combination of spicy and sweet.


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FTC Disclosure: This post contains affiliate links. When you click through my link and make a purchase, I may earn a small commission on your sale. This helps me cover a portion of the cost to run GAPS Diet Journey site and allows me to continue providing free content. This has no effect on your price. You can view it like leaving a tip. Thank you for your support! ~Starlene
Shirley at Gluten Free Easily has a big giveaway going on right now until Wednesday February 27th at midnight. She is giving away 9 books in all and one of those is a copy of Beyond Grain & Dairy. She does a mini-review on each book. Enter for a chance to win one of them.


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I'm choosing to believe that Vaclav Havel's final heroic act was to somehow kill Kim Jong Il w/ his mind
I just posted the first short story I ever got published @kaffeinkatmandu. Check it out & please RT! bit.ly/rw9eES
Hey everyone! Check out my latest story JUST published in Wilderness House Lit Review! bit.ly/nylKBG Please RT
When god closes a door, he opens a window. Also when he takes off his shoes he puts on a hat. #mysteriousways
I'm both shocked & mortified that my application to be the new Dear Leader of North Korea has been ignored. Hints of nepotism, too!
My on-line novel *X* enters its final (tragic) act: bit.ly/LfpwLa Plese RT!
Before I publish Chapter 2 today, check out my Author's Intro to my Novel, X: bit.ly/xE7p7p


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From even the earliest of ages, I've adored Halloween! It's my favourite holiday and a date that I start planning (and decorating) for many weeks in advance. As such, I was surprised when the thought hit me recently that I hadn't created any Halloween themed pages yet.
I quickly remedied that problem by putting together this eclectic (any time you've got a bling spider hanging out on a rose with a butterfly, I think that happily classifies as eclectic :D) page that features a photo of me on either my 2nd or 3rd Halloween (not sure, will have to double check that with my mom some time) in a Halloween costume that my mother handmade (I loved that costume and wore it for at least three Halloweens).
I had a lot of fun putting this page together and can't wait to dig out some more childhood Halloween photos and create further All Hallow's Eve themed pages  ~ Heartfelt thanks for checking out my page. Any questions about this LO, please don't hesitate to ask. Wishing you a blissfully creative day! <3 Jessica (Scrapbooking Poetess) ~
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