text:
|Publication number
|Publication type
|Application number
|Publication date
|Jan 5, 1993
|Filing date
|Jul 23, 1990
|Priority date
|Jul 24, 1989
|Fee status
|Also published as
|Publication number
|Shuji Iwasaki, Toshi Kagayama, Kazuya Kamata, Hidechika Hayashi
|Original Assignee
|Tosoh Corporation
|Export Citation
|BiBTeX, EndNote, RefMan
|Patent Citations (11), Referenced by (23), Classifications (30), Legal Events (4)
|External Links: USPTO, USPTO Assignment, Espacenet
1. Field of the Invention
The present invention relates to an automated analyzer for assaying a specific component in a sample. More particularly, the present invention relates to an automated analyzer for assaying a specific component in a sample by using a vessel which contains reagents therein.
2. Description of the Related Art
In recent years, automated analyzers are utilized in a variety of application fields. For example, an immunoassay apparatus for assaying an antigen or an antibody in a sample such as blood, plasma, and the like by utilizing an antigen or an antibody is utilized in a clinical diagnostic field.
In this specification, the present invention is described, as an example, regarding an immunoassay apparatus, particularly an automatic analyzer for conducting enzyme immunoassay by use of an enzyme-labelled antibody (or antigen). (Hereinafter the term "enzyme immunoassay" is referred to as "EIA".)
The EIA is a method for assaying a small amount of a component in a sample (Clinical Chemistry, Vol. 22, No. 8, 1243-1255, 1976). In a sandwich method therefor, the specific component to be assayed is captured by an appropriate antibody (or antigen) immobilized on a suitable solid phase material; then an enzyme-linked antibody or antigen (a conjugate) capable of reacting with the component to be assayed is brought into contact therewith to form an immune complex; the excess of the conjugate is removed; a substrate is added thereto which will output a detectable signal (such as change of absorbance, change of fluorescence intensity, etc.) by an activity of the enzyme; the signal is measured to determine quantitatively the amount of the enzyme according to a preliminarily prepared calibration curve; and from this the quantity of the specified component is estimated.
In this method, since different reagents, namely antibodies or antigens, are required corresponding to specific components to be assayed, the reaction vessels are provided in which different reagents are sealed up respectively corresponding to the specific components to be assayed, and are appropriately selected and used.
One of the example of automated analyzers for EIA is described in JP-A-62-148858 (The term "JP-A" as used herein means an "unexamined laid-open Japanese patent publication"), which comprises; means for dispensing a sample, means for breaking the top seal of a reaction vessel, means for dispensing a substrate, means for measuring, means for transferring reaction vessels.
In case where the concentration of the specific component is extremely high or extremely low, the detection ability of the reagent sealed in a reaction vessel is, usually, preliminarily adjusted to cover a wide range concentration of the specific component, or otherwise sample volume is adjusted according to the analyte.
In other words, conventionally, the assay is performed at a fixed sample volume for analytes which can be assayed at the sample volume, and thereafter the assay is performed for other analytes regarding the same or different samples at different sample volume.
In another practice, for the purpose of avoiding a repetition of the assay regarding the same sample, the sample volume is changed for every analyte by using an external input device such as a keyboard.
However, it is not desirable to perform the assay firstly for selected analytes for which the same sample volume is acceptable and then to perform the assay for other analytes for which a different sample volume is acceptable, because such operation takes much time and at least one operator have to be engaged therein. Further, the input operation of sample volumes by an external device for respective analytes requires at least one operator and artificial input errors may cause serious mistakes to assay results. These are the disadvantages which are to be solved by the present invention.
The present invention intends to provide an automated analyzer which utilizes reaction vessels containing respectively different reagents according to analytes, or specific components to be assayed.
The present invention provides an automated analyzer for automatically assaying a specific component in a sample by utilizing a top-opened reaction vessel; which contains a reagent capable of reacting with the specific component, and which is sealed with a seal foil on which a symbol for the reagent is shown: the analyzer comprises means for breaking the seal foil, means for dispensing a sample to the reaction vessel, means for measuring a reaction signal caused by a reaction with the specific component and the reagent, means for transferring the reaction vessel and means for discriminating the symbol shown on the seal foil, which is placed at a position on a transfer route of the reaction vessels transferred by the transferring means and at a position before the seal-foil breaking means.
The present invention further provides an automated analyzer, suitable for performing a sandwich EIA method, for automatically assaying a specific component in a sample by utilizing a top-opened reaction vessel containing a reagent capable of reacting with the specific component, which is sealed with a seal foil on which a symbol for the reagent is shown: the analyzer comprises means for breaking the seal foil, means for dispensing the sample to the vessel, means for separating a liquid component keeping a solid component in the reaction vessel, means for dispensing a second reagent other than the reagent sealed in the reaction vessel, means for detecting a reaction signal caused by a reaction with the specific component and the reagent, means for transferring the reaction vessel to the measuring system, and means for discriminating the symbol shown on the seal foil, which is placed at a position on a transfer route of the reaction vessels transferred by the transferring means and at a position before the seal foil breaking means.
FIG. 1 shows a constitution of the automated analyzer of the present invention.
FIG. 2 shows an external shape of the reaction vessel and a reagent sealed in the vessel.
FIG. 3 illustrates an outline of means for discriminating the symbol.
FIGS. 4(a)-4(d) show light diffusers.
FIG. 5 shows an example of a video image, where the abscissa shows the distance in diameter direction in the reaction vessel, and the ordinate shows reflection level of reflected light.
FIG. 6 and FIG. 7 show examples of discrimination symbols printed on the seal foil.
FIG. 8 shows assay parameters depending on or independent of analytes.
FIG. 9 shows an example of a calibration curve showing the relation of a detected signal with a concentration of a specific component to be assayed.
The present invention provides an automated analyzer for automatically assaying a specific component in a sample by utilizing a top-opened reaction vessel which contains a reagent capable of reacting with the specific component and which is sealed with a seal foil showing a symbol for the reagent. The analyzer of the present invention is useful, for example, as an automated analyzer for assaying a toxic substance in water, and as an automated analyzer for the above-mentioned immunoassay.
The symbols for denoting the reagents shown on the seal foil are not limited to technical terms of compounds or the like contained in the reagents. For example, alphabets like X and Y may be used. Any symbols are useful which enable discrimination of a reaction vessel for a specific component to be assayed from other reaction vessels. In the case of EIA, for example, the signals generated by the reaction may vary depending on the production lots even though a same quantity of a specific component is subjected to the assay. In such a case where each calibration curve suitable for the respective lot has to be selected, symbols for the production lot may be denoted to select the calibration curve for calculating assay results according to the production lot, and the analyzer may be controlled by use of the symbols.
In case of utilizing a cylindrical reaction vessel, it may be difficult to discriminate the symbol because the symbol would be upside-down as the result of rotation of the vessel. To meet the difficulty, it is preferred to show an additional symbol for indicating the direction of the symbol: for example, a lateral bar is shown under the symbol of a reagent.
A reagent sealed up in the reaction vessel is to be capable of reacting with a component to be assayed. A reagent to be used in EIA, for example, is an antibody if the component to be assayed is an antigen, or is an antigen if the component to be assayed is an antibody. In a "one-step sandwich method" and the like, there may be enclosed in the reaction vessel, as the reagent, an antibody or antigen acting on the component to be assayed and additionally an enzyme-labelled antibody or antigen. The reagent need not be limited to one compound but may be a mixture of compounds for assay of the specific component. In particular, in EIA, an antigen or antibody capable of acting on a specific component may be combined to a suitable solid-phase in order to separate excess of the conjugate. The solid-phase may be an inner wall of the reaction vessel, or may be a bead-like article. The reagent in this invention include such solid-phase.
The seal foil has desirably a superior sealing property and is made of a material which is breakable readily by means for breaking. The examples are metal foils such as of aluminum and the like, and laminated foils of aluminum with a plastic. Such a seal foil is heat-sealed or bonded on the external rim of the reaction vessel to close it tightly.
The means for breaking the seal foil to open the reaction vessel for the subsequent sample dispensing. For example, some means are disclosed in JP-A-62-273456, but the means for breaking is not limited thereto. Any means is useful therefor which is capable of removing the whole or a part of the seal-foil closing the reaction vessel to allow the subsequent operation to the reaction vessel.
The means for dispensing sample dispenses the sample to be assayed into the reaction vessel. The examples thereof are disclosed in JP-A-61-254833, JP-A-63-106567, etc. Methods or apparatuses for dispensing a sample with high accuracy are disclosed in JP-A-62-182665, etc.
The means for measuring detects a measurable signal generated in relation to the specific component in the sample to be assayed with reagents sealed in the reaction vessel. For example, in EIA, the antibody and the enzyme-labelled antibody as reagents react with an antigen to be assayed to form a complex, which will generate a signal in relation to the specific component when a substrate which causes a detectable change by an enzyme activity is added thereto. An example of such a device is disclosed in JP-A-62-034039. Color, absorbance, fluorescence, luminescence and the like are utilized as the signal. The measuring device is suitably constituted in accordance with the signal.
The means for transferring a reaction vessel transfers the reaction vessel to the positions for assaying the specific component in the sample as mentioned above. The means is exemplified by a transferring device having a constitution such as those disclosed by JP-A-62-148858. Such a transferring device is constituted of a plate for holding the reaction vessel and a means for transferring the plate. The transferring means of the present invention may be equipped with a temperature controlling means for maintaining the reaction vessel at a constant temperature, if necessary. To perform the EIA, for example, if the solid-phase contains a magnetic material as disclosed in JP-A-62-197425, a stirring means for stirring the solid-phase may be provided. Such a transferring means equipped with a temperature-controlling means and a stirring means is also disclosed in the aforementioned JP-A-62-148858, and a stirring means is disclosed, for example, in JP-A-62-036182.
The means for discriminating symbol is not specially limited if it is capable of recognizing the symbol shown on the seal foil. The means may be constituted of a light source, a lens for receiving the light of the light source reflected on the foil surface, and a means for discriminating the symbol from the intensity or the like of the reflected light, or otherwise the means may be a conventional bar-code reading device if conventional bar-code is used as the symbol. Specifically, a video camera may be utilized as the symbol discriminating means. The video camera may be of a black-and-white type or of a color type, and in particular, the number of picture elements is not limited. The camera may comprise a CCD (charge coupled device), or a vidicon tube. The one utilizing the CCD is preferable because of its relatively small size.
The discriminating means is placed at a position on a transfer route of the reaction vessel, and preceding the position where the seal is partly or wholly broken by the seal-foil breaking means.
If a video camera is used, a seal-foil illuminating means is preferably equipped in combination so that the video camera may discriminate the symbol satisfactorily. The seal-foil illuminating means is constituted, for example, of a light diffuser, a light source provided outside the light diffuser, and an opening. Such a seal-foil illuminating means is placed at a position between the video camera and the seal foil. Accordingly, the opening of the device comes to be located between the lens of the video camera and the seal foil. Since the output from the video camera is a picture image output, a video signal treating device, which is constituted of a memory and a computor, may be equipped for treating the output.
The light diffuser is in such a shape that it covers the nearly the whole of the seal foil (nearly 2π radian as the solid angle). The shape, for example, may be of a semisphere, a cylinder, a polygon, a polyhedron, or the like. The diffuser is made of a transparent material or a translucent material so that the seal foil may be illuminated by an external light source. Accordingly, the light projected by the external light source is diffused by the diffuser to illuminate the seal foil on the reaction vessel as well as the other parts of the interior of the diffuser. A portion of the light which is projected to the inside of the light diffuser is irregularly reflected further to illuminate the seal foil of the reaction vessel and other parts of the light diffuser, while another portion of the light transmits the light diffuser to illuminate the outside of the diffuser. The light diffuser is preferably roughened at the internal surface and/or the external surface, or made of a material which absorbs light less and is superior in light diffusion properties so that the transmitted light and reflected light can diffuse and illuminate uniformly the seal foil of the reaction vessel. The examples of the material include milky white glass (opal glass), milky white plastics, and the like. The light source may be a light emitting diode, an incandescent lamp, or the like.
The symbol-discriminating means described above enables the recognition of the reagent which is sealed up in the reaction vessel. According to the recognition of the reagent, the reaction vessel can be recognized as to which of the specific components the reagent is directed to. Therefore, the sample volume can be changed automatically to an optimum level by providing a controlling device to control the aforementioned sample dispensing means so that an optimum amount of the sample may be dispensed for assay of the specific component. In the present invention, not only to control the sample volume according to the symbol discriminated by the symbol-discriminating means, but an apparatus may also be constituted, for example, in such a manner that an additional reagent-injection means, which dispenses another reagent at an appropriate time during the assay, is controlled to be operated only when the reagent is needed. It is also possible to control a diluent-dispensing means to dilute the sample, and further control the diluent volume in the case where the content of the specific sample is presumed to be high and dilution of the sample is needed. Moreover, in EIA for example, when the signal generation by an enzyme in a conjugate is presumed to be low, it is also possible to control the analyzer to lengthen the reaction time of the enzyme with a substrate (the time from addition of the substrate into the reaction mixture to measurement of the signal), or lengthen the time of measurement in order to increase the enzyme reaction product.
Additionally to the automated analyzer described above, there may be provided a means for separating a liquid component with the solid-phase component being kept in the reaction vessel, or a means for dispensing a reagent other than the reagent sealed in the reaction vessel, thereby constituting a suitable automated analyzer for immunoassay, particularly for EIA. In the EIA, where a conjugate is used, the excess of the conjugate which has not combined to the specific component to be assayed has to be removed, because the reagent sealed in the reaction vessel comprises an antigen or an antibody capable of reacting with the specific component immobilized on an appropriate solid-phase and an enzyme labelled antigen or antibody (conjugate), and the specific component to be assayed comes to combine indirectly with the solid-phase according to an antigen-antibody reaction. For this reason, the aforementioned separating means is necessary.
The separating means is of any type which is capable of separating the component other than the solid-phase, namely a liquid component, in the reaction vessel. Such means are disclosed, for example, in JP-A-62-273453, JP-A-63-012959, etc.
In the EIA, the reagent other than the reagent sealed in the reaction vessel includes a substrate for the enzyme in the conjugate. A dispensing device for dispensing such a substrate is exemplified by the one disclosed, for example, in JP-A-62-148858.
The automated analyzer of the present invention may be equipped, if necessary, with a means for feeding the reaction vessel to the transferring apparatus as shown, for example, in JP-A-62-289763, and JP-A-63-015164, and a device for discharging the used reaction vessel as shown in JP-A-62-289762.
The present invention can perform the assay automatically without troublesome preliminary operations which are conventionally necessary before performing the assay.
By use of the analyzer of the present invention, only by setting a reaction vessel into the apparatus, the symbol shown on the seal foil of the reaction vessel is read out, the analyte is discriminated, and the subsequent operation may be performed such as the aforementioned change of the sample volume, and additional dispensation of a special reagent. Hence, the present invention can solve problems which impede automation of assay in conventional analyzers.
In particular, the assay time is shortened owing to needlessness of preliminary operation before the assay even when the analytes are to be selected for every sample independently.
Moreover, no artificial mistake occurs since there is no need for inputting any information about the analytes with a keyboard or the like.
The present invention is described in more detail referring to the figures.
The automated analyzer of the present invention is applicable to various conventional analysis. As an example, FIG. 1 illustrates a constitution of an immunoassay analyzer for assaying an antigen or an antibody in the sample by an EIA method according to the present invention.
A sample such as blood, and plasma, is put into an appropriate container, and the container held by a holder or the container itself is transferred by a transferring device 1. The sample transferred to a sample dispensation position A on a sample transfer route is dispensed into a reaction vessel having reached the dispensation position B by means of a sample-dispensing means 5. The reaction vessel held by a suitable holder, or the reaction vessel itself, is transferred by reaction vessel transferring device 2 in the direction denoted by the arrow mark. On the transfer route, the following means are arranged; a symbol-discriminating device 3 at an analyte-discrimination position C, a seal-foil-breaking device 4 at a seal-breaking position D, a sample-dispensing device 5 at a dispensation position B, a separating device 6 at a Bound/Free (B/F) separation position E, a dispensing device 7 at a substrate-dispensation position F, and analyzing device 8 at a optical measurement position G. The measuring system and the transfer device are controlled by a control device 10.
Firstly, the symbol shown on the seal foil of the reaction vessel is discriminated at the position C. The information from the discrimination device is transmitted to a separate control device 10. Subsequently, the seal foil is broken, and the sample is dispensed. The sample volume to be dispensed is controlled by the control device in response to the information from the discriminating device so as to feed a suitable quantity of the specific component (or the analyte) to be assayed. After the dispensation of the sample, the reaction vessel is transferred to the Bound/Free (B/F) separation position E where the excess of the conjugate in the reaction vessel is separated. Then the substrate for the enzyme is dispensed, and the signal generated in relation to the specific component is measured by the measuring device 8 at the optical measurement position C.
This apparatus is equipped with a data-analyzing device 9 for calculation regarding the measurement signal on the basis of a preliminarily inputted form, and an inputting device (an operating panel 11) for accessing the data-analysis result or directing start or stop of the apparatus.
FIG. 2 illustrates a reaction vessel applicable to the analyzer of the present invention. The reaction vessel 12 contains a solid phase 14 for B/F separation performed in EIA, an antibody (or an antigen; not shown in the figure) immobilized on the solid phase, and a conjugate (not shown in the figure). Usually, such reagents for EIA are lyophilized with optional stabilizing agent into a form of a bulk 15 as a whole, and is enclosed in the vessel. The side face 13 of the reaction vessel is not specially limited in its shape, etc., but is preferably in a shape suitable for being held tightly by a holder if the vessel is transferred by means of a holder.
On the seal foil 16 sealing the reaction vessel, a symbol is shown which denotes the reagent sealed up in the reaction vessel. In this example, the symbol "IGE" denoting immunoglobulin E together with the symbol "06" denoting a lot number of the reagent shows the reagent sealed up in the reaction vessel. While such symbols may be used which can be discriminated visually by an operator, a symbol like X, or Y which does not have meaning by itself may be used as shown in FIG. 6 and FIG. 7.
FIG. 3 illustrates an arrangement at the analyte discrimination position C in FIG. 1. A light diffuser 19 is placed above a reaction vessel 12 so as to cover the seal foil, and further above it, a video camera 17 is placed. An opening (not shown in the figure) is provided at a portion of the light diffuser on the line from the seal foil to the lens of the video camera. A light source 19a directs light onto the seal disc 16 for reflection into the video camera. The image output from the video camera is transmitted to a video signal processor 18, and further transmitted to the control device shown in FIG. 1. The video signal processor may be constituted of a memory and a computer.
FIG. 4 illustrates light diffusers for constituting a seal-foil-illuminating device which is preferably combinedly used with a symbol-discriminating device comprising a video camera in the present invention. The illustrated light diffusers are in shapes of a semisphere (a), a cylinder (b), a pyramid (c), and a polyhedron (d).
FIG. 5 shows an example of video images in the case where, referring to FIG. 4, the reaction vessel is sealed with a circular seal foil of 7 mm in radius, a cylindrical light diffuser of 15 mm in diameter and 30 mm in height made of milky white plastic is placed above the reaction vessel, and the seal foil is illuminated by each five light-emitting-diodes as light sources placed outside the light diffuser at the two heights of 10 mm and 20 mm from the bottom face of the diffuser and at an equal spacing corresponding to a central angle of 72�. In this Example, the image is obtained by use of a black-and-white CCD camera. The background is illuminated uniformly. The reflection level 21 of the symbol is clearly distinguishable from the reflection level 20 of the background.
FIG. 6 and FIG. 7 show examples of symbols shown on the seal foils. On the seal foil 16, a symbol 22 denoting an analyte, and production lot of the reagent sealed up in the reaction vessel, a dots symbol 23a, 23b therefor, or a bar-code denotation 23c is shown. In both figures, the lateral lines 24 at the lower sides are symbols for detecting the direction of the symbols or of the reaction vessel.
FIG. 8 shows the assay parameters 25 which depend on analytes and the assay parameters 26 which are independent of analytes. The controlling device 10, on receiving a signal from the symbol-discriminating device, decides the operations to be changed for the reaction vessel showing the symbol, and control the measurement apparatus to perform the assay.
FIG. 9 shows an example of the preliminarily prepared calibration curves which gives a correlation between the signal and the concentration of the specific component (IGE) in EIA. Such data are stored in a data analyzer 9 in FIG. 1, for example.
Such a calibration curve may depend on the production lots provided for assaying the same analyte. Accordingly, the data processor may be constituted to store several calibration curves for one anaylte, and to select one of the calibration curves suitable for the lot in accordance with the symbols shown on the reaction vessel.
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|Storage Technology Corporation
|Encoded label having redundant and scrambled indicia for identifying a magnetic tape cartridge
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|Image Recognition Equipment Corporation
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|Toyo Soda Manufacturing Co., Ltd.
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|U.S. Classification
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|International Classification
|Cooperative Classification
|European Classification
|Aug 28, 1990
Owner name: TOSOH CORPORATION, JAPAN
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST.;ASSIGNORS:HAYASHI, HIDECHIKA;IWASAKI, SHUJI;KAGAYAMA, TOSHI;AND OTHERS;REEL/FRAME:005429/0720
Effective date: 19900817
|Jun 24, 1996
|Fee payment
Year of fee payment: 4
|Jun 26, 2000
|Fee payment
Year of fee payment: 8
|Jun 2, 2004
|Fee payment
Year of fee payment: 12


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Cherrie ShortAssociate Dean USC School of Social WorkGlobal & Community Initiatives, Center for Asian-Pacific Leadership
Cherrie Short has spent her entire working life fighting for social justice and equal rights for all people. An experienced advocate, she has negotiated and mediated agreements across a broad range of statutory, voluntary and commercial organizations, and has raised funds for advocacy groups. Accomplished in virtually all aspects of social work, including direct practice, policy development and accreditation, Short has lived most of her life in Wales, where she served in a number of important positions, including on the Commission of Racial Equality.
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INGREDIENTS: Water (Aqua), Magnesium Ascorbyl Phosphate, Propylene Glycol, Yucca Schidigera Extract, Calendula Officinalis Flower Extract, Anthemis Nobilis Flower Extract, Camellia Oleifera Leaf Extract, Cucumis Sativus (Cucumber) Fruit Extract, Glycyrrhiza Glabra (Licorice) Root Extract, Ascorbic Acid, Ascorbyl Glucoside, Retinyl Palmitate, Tocopheryl Acetate, Polysorbate 20, Hydroxyethylcellulose, Citric Acid, Butylparaben, Ethylparaben, Isobutylparaben, Methylparaben, Phenoxyethanol, Propylparaben, Sodium Hydroxymethylglycinate


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The the Forward Channel
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South Africa Forces New Israeli Product Labels: 'Made in Israeli Occupied Territories'
South Africa Forces New Israeli Product Labels: 'Made in Israeli Occupied Territories'
Some Israeli products sold in South Africa will no longer carry the label "Made in Israel." A new law will require vendors to distinguish between consumer goods made in Israel and those made in the West Bank or what is also called Judea and Samaria. Anything manufactured in the Jewish settlements will now carry the label "Made in IOT" or the Israeli Occupied Territories. South Africa is the first country to legally require this kind of label and it has provoked a very angry response here in Jerusalem. Israeli Foreign Ministry officials are calling the law totally unacceptable and discriminatory... "It brings to mind ideas of a "racist nature" which the government of South Africa, more than any other, should have wholly rejected" -- that is how the Foreign Ministry described the new law in their official response... Its's true -- South Africa has not mandated new product labels for any other countries where territorial disputes exist...it has no prior record or uniform policy on the issue. Israeli officials say the new law is all about taking political sides in the Israeli-Palestinian conflict...South Africa's objective, they believe, is to support an economic boycott of the Jewish settlements, a step endorsed by pro-palestinian groups...by punishing Jewish businesses in disputed areas, they can show solidarity with the Palestinians and strengthen their own political position... South Africa, like most of the international community, considers the Jewish settlements in the
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Entry requirements
Normally you need a 2:2 honours degree or above in any discipline from a UK university or equivalent from an overseas university. We also consider applicants who do not meet these academic criteria but have several years' experience and a keen interest in computing. Overseas applicants from countries whose first language is not English must normally produce evidence of competence in English. An IELTS score of 6.0 with 5.5 in all skills (or equivalent) is the standard for non-native speakers of English. If your English language skill is currently below an IELTS score of 6.0 with a minimum of 5.5 in all skills we recommend you consider a Sheffield Hallam University Pre-sessional English course which will enable you to achieve an equivalent English level. International and European entry qualifications If you are an International or non-UK European student, you can find out more about the country specific qualifications we accept on our international qualifications page.
Months of entry
Course content
Study a course designed for non-computing graduates who want to pursue a career in the IT industry. You gain knowledge of key computing topics then have the opportunity to specialise in a subject relevant to the current job market. Your learning is enhanced by an industrial expertise module where you work on real-life projects and briefs.
• Use the course to move into computing from an unrelated discipline.
• Study subjects relevant to today's IT job market including programming and project management.
• Choose to specialise in databases, big data or web development.
• Gain industry experience working on live projects for real clients.
Information for international students
Please visit our website at http://www.shu.ac.uk/international
Fees and funding
Scholarships, discounts and bursaries may be available to international students who study this course. Visit http://www.shu.ac.uk/international/scholarships-bursaries to find out more.
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- Faculty of Arts, Computing, Engineering and Sciences
- email@example.com
- Phone
- +44 (0)114 225 5555


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Sunday Steals: 10 Awesome Indies for $3 or Less
Here are some great deals on quality reads featured here at Awesome Indies. Prices listed here are good as of today, but may change without notice– please be sure to double-check prices before clicking purchase. And as ever, we hope you'll take a moment to write a review if you enjoy the book!
Contemporary Fiction
Title: God of Wine
Author: Elizabeth Zahzam
$.99 Amazon U.S.
£.77 Amazon UK
Synopsis: "Greek tragedy meets Sex In The City"
When god Dionysus manipulates the lives of two struggling performers, the consequences are as dramatic as theatre itself. God of Wine is a dark tale of alcoholism, obsession, and a decision that will mean life or death to a troubled Broadway star.
Title: Portisville
Author: Steve Cushman
$.99 Amazon U.S.
£.77 Amazon UK
Synopsis: Jimmy Wills, a 34-year-old house painter living in the mountains of North Carolina, gets a telephone call from his dying father in rural north Florida. His father demands that Jimmy come home to kill him. Jimmy knows he won't do what Truman Wills has demanded, but he finds himself drawn to the place of his birth by forces he isn't quite able to name.
He discovers that the town is remarkably the same. One of his father's best friends is still the sheriff and the other is the keeper of the general store. But in the course of his three-day visit, Jimmy begins to uncover dark and disturbing secrets from the past, including the truth about the murder of his mother. Although Truman was charged with the killing, he was later acquitted, and the crime has remained unsolved.
The murdered woman still haunts the dreams of her son, who was taken away at the age of 14 and raised by an aunt in North Carolina. Jimmy has tried since then not to think too much about his father. But when Jimmy pulls up to his father's house, the two men slowly begin to reconnect, with all of the promise and tragedy that entails.
Contemporary Women's Fiction
Title: Can't Live Without
Author: Joanne Phillips
$2.99 Amazon U.S.
£1.91 Amazon UK
How does it feel to lose everything you own?
Author: Karen S. Bell
$2.51 Amazon U.S.
£1.95 Amazon UK
Synopsis: Suze Hall is at a crossroads. Her nemesis at work, Wanda, has been promoted and now will be her boss. Her husband, Bob, is leaving her and the three kids for a six-month sabbatical down under. To top it off, her best friend, Marcia, is missing in action—playing footsie with some new boyfriend!Adding to this disaster stew, David, the gorgeous hunk who broke her young-girl's heart has coincidentally popped back into her life and has something she desperately needs to keep her job.So step into the shoes of Suze Hall and commiserate over workplace politics, titillate your sexual fantasies, ride the wave of a working mother, and fall-down laughing.
Paranormal/Urban Fantasy
Title: A Matter of Perception
Author: Tahlia Newland
$.99 Amazon U.S.
£.77 Amazon UK
$.99 Barnes & Noble
$.99 Kobo
Synopsis: Take a journey into a world where the hidden becomes manifest and the lines between fantasy and reality blur. This collection of imaginative and entertaining stories about ghosts, sirens, light spectrum mages, realm hopping gods, alien monsters and ordinary people will warm your heart and make you smile, shiver, and maybe even wonder about the nature of reality itself. The theme of individual perception as a result of our assumptions, beliefs and emotional experience bind these otherwise diverse stories into a unified whole.
Title: Amaretto Flame
Author: Sammie Spencer
$.99 Amazon U.S.
£1.91 Amazon UK
Synopsis: When Olivia Landry screams, people die. No wonder she's been shunned by humans her whole life. When Olivia makes a huge mistake, she's banished for a summer to a human town; forced to live as one of them. She's out for revenge when she discovers the humans are different than she imagined, especially the rugged, sexy guitarist, Jackson Vance.
Pretending to be human isn't as hard as she thought it would be…until the witch hunters attack. Now Olivia must somehow protect herself, her family, and her new human friends. There's a problem with that. When you go around screaming, people are bound to learn your secret. Can love really conquer anything?
Title: Fire Baptized
Author: Kenya Wright
$2.99 Amazon U.S.
$2.99 Barnes & Noble/Nook
$2.99 Kobo
Synopsis: Set in a caged habitat, where supernatural beings have been trapped by humans, the dark fantasy Habitat series follows Lanore as she solves mysteries while struggling for equality in the face of prejudice among supernaturals.
Since the 1970s humans have forced supernaturals to live in caged cities. Silver brands embedded in their foreheads identify them by species: a full moon for Vampires, a crescent moon for Shifters, a pair of wings for Fairies, and the list goes on, for each supernatural species has been tagged and categorized by humans. Lanore Vesta is marked with a silver X, the brand of Mixbreeds; second-class citizens shunned by society. She stays to herself, revealing her ability to create fire only during emergencies. All she wants to do is graduate college and stop having to steal to survive. But when she stumbles upon a murder in progress, she catches the attention of a supernatural killer. Now all she wants is to stop finding dead bodies in her apartment. Enlisting help from her Were-cheetah ex-boyfriend Meshack and a new mysterious friend named Zulu, she is steered through the habitat's raunchy nightlife. But their presence sometimes proves to be more burden than help as they fight for her attention. While the corpses pile up, and the scent of blood fills the air, Lanore is left wondering: Will she find the psycho or die trying?
Historical Fiction
Title: The Ice King
Author: Geoff Woodland
$1.50 Amazon U.S.
£.98 Amazon UK
$1.50 Barnes & Noble
$1.50 Kobo
Synopsis: In 1804 Liverpool was the largest slave trading port in Great Britain, yet her influential traders felt threatened by the success, in Parliament, of the ant-slavery movement. Few, in Liverpool, condemned the 'Trade'.
William King, son of a Liverpool slave trader, sickened by what he experienced aboard a Spanish slaver, was one of the few who did speak out against the Trade.
This epic, during the dying days of this despicable practice, has generational change, moral wickedness, greed, romance and the fortunes of war woven through the lives of father and son caught up in the turmoil that preceded the implementation of the British Trade Act of 1807, which would end Britain's involvement in the slave trade.
To Liverpool slave traders, if this Act gained Royal Assent, it could mean their ruin.
Title: All the Blue-Eyed Angels
Author: Jen Blood
$.99 Amazon U.S.
£.77 Amazon UK
Synopsis: The truth will set her free… But is freedom worth the price?
Investigative journalist Erin Solomon sets out to solve a mystery that's haunted her since childhood: a fatal fire at the Payson Church of Tomorrow, the isolated fundamentalist community where Erin lived with her father for the first ten years of her life. When what was presumed to be cult suicide turns out to be anything but, Erin returns to her hometown to find the truth behind the tragedy. Now, isolated on the Maine coast with an old flame and a handsome newcomer with his own dark past, Erin will risk everything to uncover the secrets of Payson Isle – secrets someone will kill to keep buried.
Title: The Temporary Detective (Humorous Mystery)
Author: Joanne Sydney Lessner
$2.99 Amazon U.S.
£3.08 Amazon UK
Synopsis: Phones, light typing…and murder.
Think breaking into show business is hard? Try landing a temp job without office skills. That's the challenge facing aspiring actress Isobel Spice when she arrives in New York City, fresh out of college and deficient in PowerPoint. After being rejected by seven temp agencies for her lack of experience, Isobel sweet-talks recruiter James Cooke into letting her cover a last-minute vacancy at a bank. New to his own job, and recently sober, James takes a chance on Isobel, despite his suspicion that she's a trouble-magnet. His misgivings are borne out by lunchtime, when she stumbles across a dead secretary in a bathroom stall. With her fingerprints on the murder weapon, Isobel sets out to prove her innocence by investigating the crime herself. While learning to juggle phone lines and auditions, she discovers an untapped talent for detective work–a qualification few other office temps, let alone actresses, can claim.
Want regular updates on the newest additions to our Awesome Indies archive, as well as the latest deals, free promos, and more? Get that and more by following us on Twitter!


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Subscriber David H. had a strange problem, or at least one that always seems strange when it happens to you:
Have a really weird situation on my XP machine — Outlook Express.
Started last week — when I use spell check, the language is
I went up to :
Tools-Options > Spelling
and sure enough, it is defaulted to French. When I use the drop down
button, the only choice I have is French.
How could such a weird situation take place? Could this be cause by a
"bug" that has gotten in to my machine?
I have used this machine for at least 7 years and routinely use Spell
Check with no problems
Thanks for any help….
I wrote back to David to say that I bet he had just installed Office 2007 or a newer version. This is a known pronblem with Outlook Express and Office 2007. I suggested that he search Google for:
outlook express french spell checker
I don't use OE, so I never had the problem, nor tried to fix it, so I can't advise him, except to two things that will force him to solve the OE issue in another manner:
1) get off XP, and
2) use Thunderbird or Outlook or something else, since OE won't run on anything past XP.
David wrote back to say:
Thanks for your quick reply Terry.
Yes, I loaded 2007 last week.
Get off XP … I did a check las
t year with a compatibility program and moving to Windows 7 was going to cost me almost $1,000 in having to buy new software programs or upgrades. I have quite a few horror stories with folks that have upgraded to Windows 8.0.
Boy, Microsoft has surely hit me with a gut punch !!
If I switch to Thunderbird, is there any way I can transfer my Folders from Outlook Express into Thunderbird ?
As I wrote last week, now with Windows 8.1 Update, I think the significant user complaints are gone, except for the Start Menu (for which I recommend the third-party add-on Start8). The horror stories of the (non)usefulness of Windows 8 have dramatically improved with the usefulness of the Windows 8 Update with Start8 (or another Start Menu add-on) if you work in Desktop mode.
My main point, though, is that it's time to put Windows XP to bed. Sure it was great for 14 years, but it really wasn't designed to be secure. Don't use XP to get on the Internet or to do email. Period.
I believe that Thunderbird will import emails and settings from Outlook Express.
The good thing is that you can try it on a transitional basis. The trick is to set Thunderbird's email account to "leave messages on the server." That way, OE is still the primary email program during your test. Set OE also to leave messages on the server. Then, that way, you can get all emails to both programs.
When you're ready to make the change, or when you're running out of email space at your Internet Service Provider, update your emails to the program(s) and then use your ISP's webmail service to log in and delete all the old emails.
Then, reset Thunderbird (which I assume you will use) to "delete messages off the server" so you don't have any long-term email capacity problem at your ISP.


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In the figure below the area of the red hexagon is exactly 3 square units. What is the area of the blue hexagon?
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The premises comprise an industrial unit suitable for manufacturing or warehousing use. The property is constructed of a steel portal frame over three bays wihtin brick and profile clad elevations. The eaves height is approximately 7m with access provided by two roller shutter doors. Office accommodation is provided over two storeys to the front elevation of the unit, which includes a canteen and toilet facilities.
AÂ yard and car parking for 47 vehicles is also provided.
Available for both lease and sale
The property is held freehold and is available on a freehold or leasehold basis with vacant possession. Terms available on application.
42 sq.ft to 42 sq.ft
To view this property or request more details, contact Savills
The information displayed about this property comprises a property advertisement. Comerty.com makes no warranty as to the accuracy or completeness of the advertisement or any linked or associated information, and Comerty has no control over the content. This property advertisement does not constitute property particulars. The information is provided and maintained by Savills.
Innovation Court, 121 Edmund Street, Birmingham, Birmingham, B3 2HJ
Call: 0121 634 8400
Masons Road, StMasons Road, Warwickshire
Northfield RoadNorthfield Road, Warwickshire
Shottery BrookTimothy's Bridg, Warwickshire


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At Gemvara, we believe that the jewelry you wear should be one of a kind, like you. That's why we make each piece to order, one at a time, just the way you want it. Choose black diamond and rose gold or quartz and white gold: it's your choice. Mix and match gems and precious metals for a look that's exactly you. It's jewelry for all life's occasions, from a birthday or Mother's Day to your own personal milestones and celebrations. Gemvara uses only the highest quality materials to craft your trillion september birthstone yellow gemstone jewelry design with meticulous attention to detail. Our precious metals are recycled or responsibly mined. September's birthstone is sapphire, the ultimate blue gem. Gemvara also offers pink, yellow, and white sapphire for September birthstones to match every outfit. Trillion cuts are a modern invention, combining the brilliant style facets of a round with the geometry of a triangle. Our wide selection of trillion september birthstone yellow gemstone jewelry by Ji Hwang, Randy Dixon, Jessica Behzad, and other talented designers means you can find jewelry that's exactly your style. You can also shop by style, choosing our Teen, Featured Set, or Statement Collections. Gemvara's fine quality trillion september birthstone yellow gemstone jewelry is designed to be passed down for generations to come, crafted by hand in the United States.
We can help right away. Chat with a jewelry expert now!


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Albert Pujols Passes Reggie Jackson in All-Time Home Run List
Los Angeles Angels' Albert Pujols points to the crowd after hitting a two-run home run during the first inning of a baseball game against the Seattle Mariners, Sunday, April 24, 2016, in Anaheim, Calif. (AP Photo/Mark J. Terrill)
Mr. October was a great baseball player, my dad's favorite. My nickname is actually from Reggie.
Jackson isn't known for his total number of home runs as much as he's known for when he hit them. An example is shown below:
So that's how he became to be known as Mr. October.
But who dares to challenge this great player?
Albert Pujols, that's who.
About an hour ago, The Machine decided that he's going to take Jackson down, to become 13th on the all-time home run list in Major League Baseball.
You can check out the video HERE.
The event is so new, it hasn't come out on YouTube yet (except…
View original post 106 more words
Posted on April 25, 2016, in MLB Reports. Bookmark the permalink. Leave a comment.


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#21,729,175 in the world and generates
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PO Box 1595, Aiea, HI - 96701, US. Phone: +1 808 528 2380 Email: rbc[AT]hakuhale.net


text:
Mixtaaaappppppes! I don't know what I'm more excited about, this month's theme or the readers we have doing it justice. Hopefully I decide by Wednesday night, and don't kick off the evening with random blubbering and "you are all so great you can just talk about whatever", and just kidding we know that's going to happen no matter what.
Jes Skolnik
Jes Skolnik is the op-ed features editor at Impose Magazine and a regular contributor to Pitchfork, Flavorwire and Paper Magazine, among other publications you may or may not have heard of. A child of DC punk, Positive Force and zine life, they have lived in Chicago for the past decade, currently residing with their partner, two rude cats and too many records in Hermosa.
Abby Sheaffer
Abby Sheaffer is the founding editor-in-chief of Chicago Literati, a nonprofit literary magazine and organization, and the founding editor-in-chief of The Vignette Review. When she is not working, she nerds out to The X-Files, Hannibal, and other shows with her adorable bulldog, Winnie.
Emily Hilleren
Emily Hilleren is a North Dakota expat and former mathlete living in Avondale. She is a founding member in The Emilies, Chicago's newest, nicest girl gang. She posts pics of thrift shop finds at @emilythrifts and co-edits the music blog Store Brand Soda, where you'll find her annual report on twee bands and sad punks at South By Southwest in March. She sometimes writes things when she's not annoying her cat with indie pop (Catimir Pulaski HATES indie pop) and is currently working on a zine about dating website profiles, which you will be able to buy at Chicago Zine Fest.
Angela Benander
Angela Benander wrote her first story titled Little Ed Under the Bed in Kindergarten and has been writing in one form or another ever since. Raised in a small town in the woods of Northern Michigan, she graduated from Albion College with a degree in political science. Angela worked for nearly 10 years on Capitol Hill as a policy aide and press secretary for two Democratic senators. In 2007, she retired from politics and moved to Chicago in an attempt to become a normal human being. She is the co-producer of That's All She Wrote, a monthly Live Lit Series in West Town. Angela has performed at Story Club, Story Lab, Solo in the 2nd City, Here's The Story and Guts and Glory and she is currently working on a novel.


text:
Student Images- Tampa Photography Classes
Free Night Photography Class 10-28-16
What a great night it was to be in downtown Tampa, see the beautiful lights, and learn about how to shoot at night. The Riverwalk is a bustling place with lots of great things to photograph. The class was about learning camera settings and long exposures and we even experimented with light painting. Great shots people!
Scott Kelby 9th annual Worldwide Photowalk 10-01-16
41 people joined me for a photowalk around Ybor city celebrating the 9th Kelby walk. This annual event drew over 24,000 walkers at 1068 walks around the world and contributed all proceeds (the walk was free) to an orphanage in Kenya! It was a great day and a great place to shoot. Photographers were challenged to do their best to tell a story about Ybor, capture motion, and shoot a cool shallow depth of field shot to compete with others on the walk. Here are some results. Thanks to everyone who came out!
Free Ybor City Safari 03-05-16
What a great day in Ybor for this safari. Over 20 people showed up for a stroll-and-shoot in the historic district. We ended up at the Saturday morning market for pictures of produce and an impromptu portrait session with Jim, a nice guy who volunteered himself for photographs. He sat as I demonstrated different lighting scenarios and participants got some nice images. It's the kind of magic you just can't plan.
Florida State Fair Safari 02-07-16
Another awesome night at the State Fair where photographers learned how to deal with night shots, capture motion, and enhance their knowledge of camera settings learned in Photo 101. Nice job!
Great job Fair Photogs!


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Bangalore (India) and Warren (NJ), April 16, 2015: Mindtree, a global technology services company, announced its consolidated results today for the fourth quarter and year ended March 31, 2015, as approved by its Board of Directors.
"We have delivered industry leading performance with a revenue growth of 16.4% for FY15. The results validate our decision to transform Mindtree to be a valued, digital partner for our clients. In this, our expertise in agile, analytics, cloud and Internet of Things (IoT) is making deep impact. What makes us additionally happy is that our customer satisfaction levels are at a record 3-year high" said Krishnakumar Natarajan, CEO & Managing Director, Mindtree.
Certain statements in this release concerning our future growth prospects are forward-looking statements, which involve a number of risks, and uncertainties that could cause our actual results to differ materially from those in such forward-looking statements. We do not undertake to update any forward-looking statement that may be made from time to time by us or on our behalf.
Mindtree [NSE: MINDTREE; CIN: L72200KA1999PLC025564] delivers technology services and accelerates growth for Global 1000 companies by solving complex business challenges with breakthrough technical innovations. Mindtree specializes in e-commerce, mobility, cloud enablement, digital transformation, business intelligence, data analytics, testing, infrastructure, EAI and ERP solutions. We are among the fastest growing technology firms globally with more than 200 clients and offices in 14 countries.
|Debi Senapati
+91 99805 56784
|Siddhartha Tanti
Genesis Burson-Marsteller
+91 99863 62435
|Imogen Nation
004420 7608 4675


text:
If you are considering building a new commercial business in South Carolina, choosing steel is a durable, efficient, and affordable choice that you will be satisfied with. Commercial steel buildings are a great choice for any business because this material has a wide range of benefits that are not available with traditional structures. At KY Steel of Winchester, Kentucky, we want to show you the benefits of choosing a commercial steel building in South Carolina.
With the wide range of temperatures that the state of South Carolina experiences, it is necessary to choose materials that can withstand every weather condition. Because steel is an incredibly durable material, these buildings will withstand the ever-changing weather without ever needing to worry about repair or damage. Steel will not warp in the high humidity in the summer, it will keep your business insulated in the snowy and cold winters, and the large amount of rainfall will not be an issue because the steel will not rust. In addition, steel buildings can withstand high winds, and earthquakes, they are fire-resistant, and will not harbor pests, termites, or mold, which the weather conditions and common insects in the state may cause with other materials.
Steel buildings are customizable in ways that traditional buildings are not. The shape of your building, the height, the number of windows, even the outward appearance and color of your building can be customized to meet your needs. Because South Carolina is known for its range of lifestyles, from traditional southern, to a laid-back beach lifestyle, or classic and modern, steel buildings are the perfect choice. You can create the perfect look for your business that is not just restricted to the industrial look that many people associate with steel.
Energy Efficiency
Steel buildings require much less energy to keep heated and air conditioned than traditional buildings. With the wide range of weather and temperature conditions in South Carolina, this is a definite benefit. You will spend less on heating and cooling costs when trying to keep up with the fluctuating weather outdoors.
Environment and Wallet Friendly
Going along with the energy efficiency of steel buildings, these buildings are also environmentally friendly in other ways. When you choose steel, you are eliminating the need for wooden framework. Buildings with wooden frames uses a large amount of wood for construction. When you choose a steel building, you can save upwards of 50 trees depending on the size of your building. Choosing steel also boosts the steel industry in the United States and allows you to have a beautifully crafted, well-designed, and affordable business that will work in any area of the state. Steel buildings will not require maintenance, the construction is simple and quick, and insurance costs are low because of the low risk of damage.
If you are ready to learn more about commercial steel buildings, or want to discuss design options, contact the experts at KY Steel today! KY Steel, proudly serving Kentucky, Ohio, Indiana, West Virginia, Illinois, Tennessee, Virginia, North Carolina and South Carolina, is your best choice for a trusted and hassle-free building experience.


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Preston dismiss duo exit
By James Pearson
Last Updated: 01/01/70 1:00am
Speculation is rife that the duo are being targeted by a number of Premiership sides for a big-money move when the transfer window re-opens, however Shaw has denied the club are to sell its key players.
When asked whether the pair could be set for The Premiership, Shaw replied to the Lancashire Evening Post: "I'd rather talk about Saturday's great result and the fact that a play-off place is still within our reach.
"We're not looking to sell anybody, especially our best players.
"I don't know where these stories are coming from. They seem to just appear.
"I'd have to say though that it would take a lot more than £1 million to take him (Etuhu) away from Preston North End.
"As for Ricardo (pictured), obviously a player of his talent is going to be attracting attention. But that's it at the moment, there has been no enquiry from anyone.
"I can assure you that we don't want to sell Ricardo. He is a marvellous player and at this moment he is our player on our contract."


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**Winners have been announced! Scroll down to see them!**
It's Week #6 and we love this challenge because it is up to YOU to show us how you are challenging YOURSELF. So, be sure to explain your photos as you share them with us (so we get the full story!) Be sure to read all the way to the end of this post!!
****If you don't see a like, or a comment from us on Instagram, Twitter or Facebook, tag us until you do! That's how you know you were counted! We just don't want to miss anyone!***
Week 6 Challenge (July 11th-17th): Challenge Yourself
Sponsored by: Teton Sports, Kelty, Seek Outside, Lightspeed Outdoors & UR Sportswear
How to participate:
- Take a Hike and Challenge Yourself!
- Snap a photo or two
- Log on to Facebook, Twitter or Instagram
- Share your photo and your experience. If you're using….
- Facebook: Share it on the wall of talesofamountainmama or hikelikeawoman
- Twitter: Share it on your own profile using the hashtag #takeahike and tag @mtnmamatales and @hikelikeawoman
- Instagram: Share it on your own profile using the hashtag #takeahike and tag @mtnmamatales and @hikelikeawoman
- Bonus points if you share a photo of your #takeahike t-shirt on this week's hike and if you share your photo on the Teton Sports, Kelty, Seek Outside, Lightspeed Outdoors & UR Sportswear social media pages.
Still need some #takeahike swag! We have t-shirts & Nalgene water bottles available right here and everything is $15.00 right now. Help us close up shop.
What you can win:
- Seek Outside $100.00 gift card (U.S.) – Steely L. – because her swag is sweet and worked past her fear of heights!
- Kelty Trail Ridge 4 (U.S.) – Lindsay S. – because, despite morning sickness and not feeling like getting out, you did anyway 🙂 And your swag rocks!!
- Teton Sports Mammoth Sleeping Bag (U.S.) – Kathryn P. – because her and her husband lost their dog this week and they got out anyway instead of staying home feeling sad!
- Lightspeed Outdoors Outdoor Blanket (U.S. & Canada) – Nicole R. because she completed TWENTY miles with her kids this week (despite it not being very popular in her area)
- UR Sportswear Outfit (U.S.) – Aubrey V. – because she gets out of bed BEFORE 4 am to hike (and we agree that we would all love to forget our adult responsibilities and just HIKE!)
BONUS!! We think that Brooke H. earns our bonus prize this week. Incredible story, incredible strength and sweet swag, Brooke!!
How we choose the winners?
Winners are selected randomly by Amelia & Rebecca. We're looking for photos and stories that inspire and motivate us and the rest of our communities. You can increase your chances of winning by wearing your #takeahike t-shirt &/or using your #takeahike water bottle when you take your hike & sharing your photos with on our weekly sponsors social media sites as well.
When will winners be announced?
Right here on our website and social media sites on Wednesday July 20th.
Help spread the word: Use these short social media messages or embed these photos to help spread the word about this week's challenge hike!
We've got a $100.00 @seekoutside gift card up for grabs this week. #takeahike for a chance to win it! @mtnmamatales & @hikelikeawoman #TreadAnywhere #Seekoutside #SeekOutsideExplorer
We're giving away a @KeltyBuilt Trail Ridge 4 tent!!! To enter you gotta #takeahike. Details @mtnmamatales & @hikelikeawoman
Cuddle up in a @TETONsports mammoth sleeping bag! #takeahike for a chance to win details at @mtnmamatales & @hikelikeawoman #hikerchat
Go #takeahike & you might win a @LSOutdoors blanket. Details @hikelikeawoman & @mtnmamatales
We're giving away a @URsportswear outfit this week! #takeahike, share a photo and you might win! @mtnmamatales & @hikelikeawoman
Thank you @seekoutside, @KeltyBuilt, @ TETONsports, @LSOutdoors, @URsportswear for sponsoring #takeahike! @mtnmamatales & @hikelikeawoman
Happy Hiking! We'll see you on the trails.
© 2016, Tales of a Mountain Mama. All rights reserved. Republication, in part or entirety, requires a link back to this original post and permission from the author.


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ROME: Talk of bond "spreads" in Italy has inspired a nickname for the grandson of PM Mario Monti, pictured.
The youngster's classmates have bestowed on him the nickname "Spread". The financial term refers to the risk premium investors demand to hold Italian bonds rather than their safer German equivalents.
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Meeting Section 501(r) Regulations
Finalized Internal Revenue Code (IRS) Section 501(r) will require tax-exempt hospitals to have certain policies and procedures in place for taxable years beginning after Dec. 29, 2015.
Hospitals will be required to meet the following summarized regulations:
- Conduct a community health needs assessment (CHNA) every three years and adopt an implementation strategy to meet the community health needs identified through the CHNA.
- Establish a written financial assistance policy (FAP) that includes eligibility criteria and the method for applying for financial assistance, and is widely publicized.
- Establish a written emergency medical care policy (EMCP) that requires the provision of care to individuals for emergency medical conditions regardless of their eligibility for financial assistance.
- Limit amounts charged for emergency or other medically necessary care provided to FAP eligible individuals to not more than amounts generally billed (AGB) to patients with insurance.
- Refrain from engaging in extraordinary collection actions (ECAs) before making "reasonable efforts" to determine whether individuals are FAP-eligible.
As part of our Private Pay Service (PPS), TruBridge will act as an extension of your hospital and ensure it is in compliance with all 501(r) regulations that are applicable to the service. We will tailor our actions to your hospital's specific billing and collection policies and procedures to ensure compliance with the new 501(r) regulations.
TruBridge will assist PPS customers in meeting these regulations by:
- Work with each customer to ensure all current policies and procedures are on file and also update any necessary call scripting.
Work with your staff to ensure the below requirements are met on billing statements:
Hospital billing statements should contain information about:
- The availability of the FAP.
- Contact information for hospital staff (or TruBridge staff) that can provide more information about the FAP and application process.
- Provide patients with a website address where copies of the FAP, FAP application form and plain language summary can be obtained.
- Hospital billing statements should contain information about:
- Share knowledge about your FAP and application process and answer any questions from your patients.
- Ensure that all statement and collection letter dates are notated in account detail as well as phone calls and any additional correspondence sent to the patient to communicate FAP availability.
The PPS department will ensure all applicable customers have the necessary information present on their billing statements and that we have a current FAP on file.
If you have any questions regarding the 501(r) regulations, please contact us today.
Section 501(r); Additional Requirements for Charitable Hospitals, 79 Fed. Reg. 250; Dec. 31, 2014


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SAN JOSE — The Sharks didn't have the benefit of a full practice to work on their ailing power play before their home game against the New York Islanders, instead making do with some brief morning drills Tuesday morning at SAP Center. But coach Todd McLellan said San Jose shouldn't need a ton of practice time to fix its woeful special teams unit.
"We adapted a little today in our pregame skate, trying to work it in a little there. Meetings are important," McLellan said. "The core of our power play has been together for six years. We shouldn't need a lot of ice time to fix it. It should be able to be done video-wise and individuals looking at themselves and their contribution level."
The Sharks enter Tuesday's game on a three-game losing streak and having scored just one goal with the man advantage in their last 18 tries. At 17.6 percent for the season, San Jose's power play now ranks 17th in the NHL. On Nov. 21, the Sharks were 10th at 20.6 percent.
McLellan stressed that for the power play to start clicking again, the execution, the commitment level and the work ethic have to improve.
"You do those three things to begin with, then you at least give yourself a chance to repair," McLellan said.
McLellan blasted the team's power play unit after Sunday's 3-1 loss to Minnesota, as the Sharks were 0-for-4 , handing the Wild more momentum with each missed opportunity.
"Last game was probably the worst in the five years that I've been here," Sharks defenseman Dan Boyle said. "I think all have to better individually and collectively we'll be better.
"It starts with me bringing the puck up, making a better play, and then just being a little sharper out there, and outworking the other team, which I think on some nights we haven't been guilty of."
Fortunately for the Sharks, they face an Islanders team that has killed just 71.1 percent of their penalties, ranking them ranked 30th out of 30 teams.


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Breakaway is the annual winter retreat of the Susquehanna Valley Presbytery. It exists to point students to Jesus Christ in everything we do. We look forward to a break from the normal routine of everyday life and an extended time away to reflect on Christ as He is revealed to us in the Word of God. Breakaway also provides plenty of opportunities to make new friends as well as strengthen current friendships. There's also plenty of good food, fun, and laughter. It all makes for a great weekend that you won't want to miss!
Important details:
Dates: February 17-19 or 20
Cost: $95 for those returning on Sunday the 19th
$120 for those returning on Monday the 20th
Registration deadline: Sunday, January 22nd
Family discount: $15 off for each additional family member
Students may apply for additional scholarship, please contact Chris at firstname.lastname@example.com for more information.
We'll leave from Westminster on Friday at 5:30pm; eat dinner before you come on Friday night. We will return to Westminster on Sunday at 9:30pm. If you are returning on Monday, we plan to return to Westminster at 2:00pm.
After Registration Refunds: ($15 limit on what you can earn)
1. $1 OFF for each 2016 TGTYH verse you can recite.
2. $10 OFF – read the daily Scripture passage and post a comment on the Treasuring God's Truth facebook page for one week.


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Don mentioned in passing yesterday that the first thing we do is fetch policy from
the remote service and then wire up the channel so that everything is in place to
adhere to that policy. I'm surprised more folks didn't catch this.
I had a chance to ask Don about this today and here's what he said. There's
this little tiny blurb in the WS-ReliableMessaging spec about Metadata
Exchange. Basically, it alludes to the need for a future specification that
would provide a way that clients MAY obtain WSDL and WS-Policy information.
That specification will be available by the end of the year.
The way it works in Indigo today is that the first message exchange includes an extra
header, marked as mustUnderstand, that says, "Hey! Give me your policy," and
we don't send a body. Since it's a mustUnderstand, if the resulting
service doesn't understand the header, a SOAP fault is generated - providing you with
a very good indication that the service you're talking to might not be very secure.
Otherwise, you get policy back and can adjust accordingly and there shouldn't be any
side effect on the service because we're not sending a message body, and therefore
there's no action to be invoked.


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Wonton Soup
Hot & Sour Soup
Sweet Chicken Corn Soup
Egg Roll
Spring Roll
Hong Kong Special Fried Rice
Chicken Fried Rice
Mixed Vegetables Fried Rice
Beef Or Pork Fried Rice
Deep Fried Dumplimgs
Canton Chow Mein
Shanghai Noodle
Chicken Lo Mein
Soya Sauce Fried Noodle
Pork Lo Mein
Mixed Vegetables
Moo Goo Gai Pan
Cashew Gaiding
Dry Garlic Chicken Wings
Mushroom Chicken Kew
Sweet & Sour Chicken
Sweet & Sour Scallops
Sweet & Sour Pork
Pineapple Chicken
Sweet & Sour Shrimp
Think your friends might be familiar with this merchant? Ask your friends on Facebook to see what they think.
It's the Chicken Soo Gai that keeps me going back again and again. The hours are great, I can get my favorites when I want them. I LOVE THIS PLACE...
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Contact us 24/7: +1 877 678 9627
View product details
Zoom In
Need a second opinion? Ask your personal shopper:
Need a second opinion? Ask your personal shopper:
GET EXPERT ADVICE Need a second opinion? Ask your personal shopper:
- - Italian sizing
- - This style runs true to size
- - Cut for a boxy fit
- - Model is 177cm / 5'10" and is wearing an IT size 40
Pull together a chic transitional look with See by Chloé's multicolored flecked tweed jacket. Partner it with your favorite jeans and a fine jersey tee for effortless weekend style. Shown here with a Marni bag, Christian Louboutin shoes, See by Chloé pants and a J.Crew top and necklace.
- Multicolored wool-blend flecked tweed jacket with puff shoulders. See by Chloé jacket has a double princess collar with a brown corduroy underlayer, brown double-breasted button fastening at neck, long sleeves with button-fastening cuffs, a half-belt at back, concealed button fastenings at front and is fully lined. 72% wool, 22% nylon, 6% mohair; lining: 98% cotton, 2% elastane. Dry clean.
Product Code: 80245
Shop more:
For alternative suggestions, contact our Fashion Consultants
Help & Advice
Product Code: 80245


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Hello, I am interested in using the content you have posted links to here. I will be teaching an intro to hospitality and tourism class next fall (high school) and I am looking for resources. Many of your links seem to be broken. Could you update them please? I am scratching my head as to how to approach this class as I have no background in the hospitality or tourism industry, just general FACS. Thank you in advance!
I'd love to see your ideas but the links don't work. Do you have updated links?
I am teaching Hospitality and Tourism this year to 9-10 graders and am interested in your lessons, but I am having trouble with the links working. Can you offer any assistance? Thank you!!


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Irma from Chicago writes,
Will Demand CS kill carpenter ants?
I'm seeing carpenter ants around my property (just like 2-3 a day). First is Demand CS strong enough to kill them? How will it kill them? And will it eventually wipe out the colony/nest/queen? If so, how long will it take? Thanks
Demand CS would be a great choice for general pest control. It will hold up well to UV rays and rain and because it is a micro-encapsulated it works a little bit like a time released formula. Of course it will only kills those pests that contacted a treated surface. We would recommend our most popular carpenter ant control product which is our Carpenter Ant Kit #2. The Carpenter Ant Kit #2 with Dominion 2L provides the best carpenter ant control available. For serious carpenter ant problems, nothing does the job better adding a product such as Dominion 2L to your arsenal. Dominion is a sprayable liquid bait that makes up to 48 gallons of solution (enough to provide several years of outdoor protection) and can be sprayed around the outside of your home to provide a long-lasting barrier against carpenter ants and other ant species. Ants pick up the Dominion 2L on their bodies and spread it to other ants, eventually eliminating the entire colony. This kit also includes Advance carpenter ant bait for outdoor control/indoor control and Maxforce carpenter ant bait gel for indoor control. The Advance Carpenter Ant Bait is great for sprinkling in a 2 foot barrier around the outside of your home to provide a food source that outside ants are looking for. It can also be applied around wood piles, trees, stumps, or other areas of harborage. Advance Carpenter ant bait can also be used indoors in bait plate stations. The Maxforce Carpenter ant bait is for indoor control only and should be placed where you see ant activity inside. The ants will eat the bait and take it back to the nest spreading it around to the other colony members. You will need a pressurized garden pump sprayer to apply the Dominion 2L.
Answer last updated on: 07/21/2014
1 of 1 people found this answer helpful. Was it helpful to you? Yes No


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If you live in the Toronto and Hamilton area, there's a real treat in store for you this weekend!
Vasyl Popadiuk, the super virtuoso violinist on his way to a global artist, will be performing live at Hamilton Place Studio Theater on Saturday August 29th @ 8:00 pm and Toronto's Assembly Hall Theater on Sunday August 30th @ 4 pm.
Ukrainian businesses and private fans of Vasyl are invited to take advantage of a sponsorship opportunity. For only $50, Vasyl will be pleased to announce your support from the stage during the performances.
To buy tickets call the box office (Toronto 416-521-9555 Hamilton 905-527-7666), online from Ticketmaster (just type in "PAPA DUKE" into the search window), or email email@example.com.
A limited block of discounted tickets @ $40 for both the Hamilton and Toronto shows can be purchased directly by calling 416-521-9555 or the Bukva Ukrainian Bookstore: 416-236-5890 (99 six points road off islington ave. Or e-email: email@example.com. No credit card sales. Cheque or cash only. Order before they are all gone!
If you're not convinced that this is a must-see concert, check out the videos below. I first saw Vasyl when he was still with the Hopak Ukrainian Folk Ensemble, which came to Vancouver circa 1993. I thought then what a marvelous talent he was, and he has only gotten better with time. He is a consummate showman as well as a rare talent ... even broken strings won't slow him down!
Enjoy the show!
Gypsy Music at the Montreal Jazz Festival
Carpathian Hoedown:


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How it Works
|Check The Availability. Enter your zip code and the move date to find available moving companies and moving help in your area.
|Get Instant Moving Quotes. Instantly compare the moving prices side by side and obtain moving quote.
|Hire the Best Mover & Helpers. Compare the moving rates, reviews and hire the mover that is best for you.
Should you go with climate controlled or conventional storage facility? There is no definitive answer to that question, there are "pros" and "cons" of each side.
Climate Control or Conventional Storage
There are times when you should not move yourself. Find out why you should hire professional help to transport your household items.
When Not To Move Yourself
MoversCorp can assist you with your DIY move. Find out what we can do for you.
Options for a DIY Move
Local moving companies and labor helpers are not permitted to transport their customers' pets. So the best way to transport pets is in the car with you.
Moving With Pets
If your move doesn't go anything like you have planned, here is little moving humor to cheer you up. However, don't take it too seriously.
How To Protect Furniture When Moving
Moving is never fun whether you do it yourself or hire professional moving company. If you move yourself, consider hiring experienced professionals to help pack and load the moving van.
Moving Labor Services
Local moving companies and professional movers in Kearsarge, 49942
Find the best local moving companies in Kearsarge at MoversCorp.com. Whether it's a big or small move, simply enter your zip code to get access to cheap moving service providers in your local area. Our Kearsarge movers provide professional moving and packing services, furniture and appliance moves, moving boxes and supplies as well as affordable moving labor services such as truck loading help and truck unloading help. Need help moving a house or an apartment, or help to load and unload a rental moving truck? Hire full-service movers and moving labor helpers in Kearsarge, Michigan through our site. You will find professional movers and move help at discounted rates. They also provide in-home furniture moving service - from one room to another or from upstairs to downstairs. Moving labor service is ideal for people who move within the home or in the same apartment complex. And if you move yourself, you can hire movers to load and unload furniture at your destination at low cost. Each moving company in Kearsarge, MI lists the services and equipment they provide.


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How To: Start and Manage Tasks
Tasks are where you'll track the day to day operations of your practice. It is important to note that tasks are the most basic way of managing your practice operations. Processes on the are a tool for your team members to efficiently manage multiple tasks. To better understand the importance of tasks and processes in PractiFI, check out our deep dive.
Here, we explain how to start a new task. Ready?
How can I start a new task?
Starting tasks can be accomplished in three primary ways: As a standalone task on the client view, as a new task within a process or simply as a personal task for a team member. These options enhance flexibility for your practice by allowing for one-off client tasks, project task management and personal task management, respectively.
- The first two methods of starting a task are accomplished from the client view, so first head to the household where you'd like to add a task. To launch a standalone task from the Processes & Tasks tab, select either Open Tasks or Completed Tasks, then select the green Add New icon. For example, if you wanted to call the client in 8 days to ask how their family vacation went, you could create a task to remind yourself to make that call. This is useful in situations where there is an important action to take for the client, but the action does not relate to a larger process or service operation.
- The second method of starting a task is within a process. Select the Processes & Tasks view, ensure you have the Processes tab selected, select the edit button next to a process and finally select the green plus sign located on the Tasks tab. This method is quite useful if new action is required on an existing process. It's quite easy to assign a new task on the fly during your daily client operations. (If you're a visual learner, see the below picture.) For more information on using Processes to improve your organization and efficiency, check out our How To: Start and Manage a Process tutorial.
- The third method for creating a task is accomplished from the team member view. First, navigate to a team member in the top nav search bar. Team members will have a small person icon to differentiate them from client accounts, etc. From this team member view, select the Processes & Tasks tab, select the Open Tasks subtab and then select the plus sign to add a new task. This area is useful for adding tasks that may be personal or for your practice rather than a specific client. Paying your utility bills, calling a vendor and the yearly spring cleaning operation are all examples of team member tasks.
- After utilizing one of the above three methods to start your task, you will first see the Task Detail screen which allows you to modify the following details:
- Subject: Write a name for the task. Try to use a concise phrase to sum up the task in just a few words, e.g. "Mail client welcome package"
- Related To: If desired, relate this task to another item in the current household. For example, another process, service or client within the same household. Services, clients, and processes in other households or families cannot be linked.
- Priority: Choose whether this task is of Low, Normal or High importance. Tasks marked High will gain a red font on the priority column, which is sure to grab attention!
- Stage: Indicate whether this task is Not Started, In Progress or Completed.
- Due Date: Pick the date this task is scheduled or required to be completed by the assigned team member. If overdue, this field will also turn red.
- Assigned To: Assign a team member responsibility for completing this individual task.
- Description: If necessary, add notes about the task in this large text area.
- Estimated Effort: Enter the projected amount of time expected to complete this task.
- Actual Effort: Enter the final time spent by the team member to complete this task.
- Variance: This field is an automatically calculated set of fields which contrast the actual and estimated effort times for the current task.
- The feed tab allows you to write individual notes, upload documents, and send chatter messages to team members. This can be useful for sharing client documents, meeting notes and/or audio files. For more information about the PractiFI feed tool, read our feeds tutorial (coming soon!)
- When finished entering all the details for your new task, select the Save button to start your new task!
How do I manage tasks?
As you've seen, starting a task is quite easy and PractiFI delivers some nice options to process a variety of situations. Managing your tasks just as simple, and it's important to understand the strategies for managing these different types of tasks. Just like starting a task, managing them is broken down into three areas: standalone tasks, process tasks and team member tasks. Remember, if you haven't created your task yet, you'll need to refer to the section above first.
- The first two methods of managing a task are still accomplished from the client view, so head to the household where you'd like to add a task. To manage a standalone task, select the Processes & Tasks tab(1) and then select either Open Tasks(2) or Completed Tasks. From here, choose the task you'd like to manage by selecting the edit icon(3). Managing a standalone task can be useful in situations such as rescheduling a phone call, changing a due date, or re-assigning the task to a new team member.
- Managing a task within a process is also accomplished from the client view. Managing tasks from the process view is most useful when needing to edit multiple tasks related to a process. For example, let's imagine a client meeting is coming up next week and Dan, a lead adviser, needs to take an emergency leave of absence. Not to worry, PractiFI makes it simple to see the list of tasks within the process for this meeting, and make corresponding edits. First, navigate to the Processes & Tasks tab (1), then select the Processes list(2). Select the edit icon(3) next to the Process which will be affected Dan's absence. Choose the Tasks list(4) and select the edit icon(5) next to each task which needs editing. In the example below, we see a financial advice process where Dan is scheduled to remind the client of their meeting, conduct the meeting and write followup notes. Since Dan is out, we can quickly reassign these tasks to another adviser, edit due dates and add any additional tasks as necessary.
- Managing a team member is accomplished from the team member view. This is the area your practice will utilize when a team member task (i.e. Paying your utility bills, calling a vendor or the yearly spring cleaning operation) changes, and quick edits are necessary. First, navigate to a team member in the top nav search bar. Team members will have a small person icon to differentiate them from client accounts, etc. From this team member view, select the Processes & Tasks tab(1), select the Open Tasks subtab(2) and then select the edit sign(3) to add a new task.
- After selecting one of the three above methods to manage a task, you'll find you can edit all the same sections created during the start of the task. For example, imagine editing a standalone task for a client who has emailed to reschedule a call. Noting you'll be in another client meeting this day, you need to need to both reschedule the call and assign to another team member.
- One helpful hint for managing tasks is that from any list of tasks, you can double-select a specific field to edit inline, rather than opening the task's popup window. This is useful for making simple edits to multiple tasks all in one swoop. An example for editing our task management scenario (#2 in this section) is displayed in the image below. Here, we change the meeting to the following week(1) and assign to another lead adviser(2). Don't forget to click save(3) after making your inline changes!
Congratulations, by understanding how to start and manage your tasks, you and your practice are well on the way to a streamlined client services operation!


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Lincoln Policy Group
People related to Lincoln Policy Group:
Robert Holifield - co-founder
Blanche L. Lincoln - founder
Colin Roskey - principal
Thomas A. Scully - principal
Other current Lincoln Policy Group relationships:
American Health Care Association - lobby firm
Cognizant Technology Solutions Corporation - lobby firm
Comcast Corporation - lobby firm
Las Vegas Sands - lobby firm
Monsanto Company - lobby firm
National Retail Federation - lobby firm
YUM! Brands, Inc. - lobby firm
Lincoln Policy Group past relationships:
American Trucking Association - lobby firm
Comcast Cable Communications Inc. - lobby firm
CropLife America - lobby firm
Experian plc - lobby firm
Interstate Natural Gas Association of America - lobby firm
Mead Johnson Nutrition - lobby firm
Valero Energy Corp. - lobby firm
Wal-Mart Stores Inc. - lobby firm
Additional Muckety map information sources:
U.S. Senate
Muckety draws information from thousands of sources. For a list of primary government and news sites, see our Sources page.
Muckety news stories featuring Lincoln Policy Group
As protesters target Wal-Mart stores across the country, the company continues its all-out lobby effort in Washington.
November 30, 2013


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'Beastly' -- 3 stars
PG-13; 1:28 running time The first good movie of the new year happens to be a "tale as old as time, song as old as rhyme." "Beastly" is a high school nonmusical update of "Beauty and the Beast." Witty, warm, well-cast and often wickedly funny, it lets Vanessa Hudgens shine and Alex Pettyfer give a hint of what all the fuss over him is about. Pettyfer is spot-perfect playing handsome, vain and cruel Kyle, the son of a rich TV anchor (Peter Krause) who taught him that "people like people who look good." Thus, Kyle's lifelong aversion to "hatchet faces, guts with butts" and "fattycakes." But Kyle, the arrogant king of Buckston Academy, is playing with fire when he taunts the school's resident witch. -- Roger Moore Read the full review
Hartford Stage's 'Christmas Carol' Has A New Scrooge
Larry Willis At The Side Door
Rapper, fashion star Lil Peep dies; drug overdose suspected
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