text:
|Publication number
|Publication type
|Application number
|PCT number
|Publication date
|Jul 7, 1998
|Filing date
|Jul 4, 1994
|Priority date
|Jul 3, 1993
|Fee status
|Also published as
|Publication number
|Michael Ralph Rees
|Original Assignee
|Medical Miracles Company Limited
|Export Citation
|BiBTeX, EndNote, RefMan
|Patent Citations (12), Referenced by (72), Classifications (18), Legal Events (7)
|External Links: USPTO, USPTO Assignment, Espacenet
This invention relates to a novel apparatus for use in angioplasty, and to a method of carrying out angioplasty.
Angioplasty is a technique for treating constriction of a blood vessel or heart valve by introducing a balloon into the constriction to widen it. A blood vessel may be a coronary vessel or a peripheral vessel. A hollow needle is generally inserted into the femoral artery. A guide wire is pushed through the needle into the artery, then along it, with the aid of imaging equipment, towards the blood vessel or heart valve to be treated. If there is a stenosis (narrowing) through which the guide wire can pass, it is advanced through it. A catheter is then threaded over the guide wire and pushed along it until it reaches the constriction. The catheter has an end region which can be inflated to form a balloon. The balloon is inflated and deflated, generally a few times, to widen the constriction, and then withdrawn. Sometimes the catheter is already engaged on the wire as the wire is advanced, the distal end of the wire extending beyond the distal end of the catheter.
There is a wide variety of balloon technology available. Balloons of various sizes from 1.5 mm to 30 mm in diameter may be obtained.
A problem arises when a blood vessel or heart valve is so occluded that the guide wire cannot simply be passed through the occlusion. A plethora of techniques has been proposed to overcome this problem. Work has been done on laser systems, but it has proved difficult to find a system which will ablate an occlusion without causing damage to the surrounding tissue. Thermal damage from continuous wave lasers can be very extensive whilst pulse lasers may have a smaller effect on surrounding tissues, but often fail to deliver sufficient energy over a large enough region to effect ablation. Mechanical devices have also been proposed. For example, the Kensey catheter employs a blunt rapidly rotating cam together with a fluid jet which creates a vortex at the tip of the catheter. The occlusion is pulverised by a combination of mechanical energy and the action of the fluid jet forming small particles which are dissipated into the blood stream. However, a high number of perforations and dissections in severely diseased vessels, where the arterial wall is calcified and therefore less compliant, have been observed. A lower speed rotational device known as the Rotacs system has also been used. Such a device is not designed to ablate an occlusion, but to provide some mechanical energy to the wire, to enable it to find the path of least resistance through an occluded vessel. However, the success rate with such a device is not very high.
A further idea has been to use hydrophilic guide wires, introduced by standard manual procedures. These are proprietary wires, thought to be of tantalum or stainless steel, coated with a proprietary material to make them slippery. This is thought to help them to take the path of least resistance through an occlusion. These wires are simple to use but a significant disadvantage is that there is a tendency to effect a sub-intimal passage of the wire past the occlusion. That is to say, the wire , tends to find a route through the wall of a vessel, rather than through the central region of an occlusion.
Despite the substantial earlier body of work aiming to devise a system to improve angioplasty as applied to occluded vessels and valves, no prior system has been wholly satisfactory.
In accordance with the present invention there is provided apparatus for use in angioplasty, comprising a catheter, a wire which serves as a guide for the catheter and whose distal end extends, in use, beyond the distal end of the catheter, and a drive unit which is coupled to the proximal end of the wire so as to vibrate the proximal end.
Preferably the catheter comprises means to act upon a blood vessel to improve or restore its function. Thus, it may comprise an expandable balloon at its distal end, although other forms of catheter may be used.
In use, the wire is fed through blood vessels to an occlusion. The catheter may then be introduced into the body, by being passed along the wire. Alternatively, and preferably, the catheter may have already been located on the wire as the wire was fed up to the occlusion, or may have been pushed in without the wire. In the region of the occlusion, once the apparatus is to be used to vibrate the wire, the distal end of the wire extends beyond the distal end of the catheter. The drive unit is then operated to vibrate the proximal end of the wire. The vibration passes along the wire and, at the distal end of the wire, this vibration is thought to be diffuse in nature; even if, as is preferred, the vibration imparted to the wire at the proximal end is predominantly or wholly a reciprocating motion. In any event, whatever the nature of the vibration of the distal end of the wire, it has been found, in preliminary confidential trials, that the wire readily finds or forms a central passage through the occlusion. It appears that the vibrating wire may alter the characteristics of the plaque which makes up the occlusion. Furthermore the vibration of the wire and/or the consequent vibration of the catheter, appears to relax the blood vessel. Once the wire has passed through the occlusion, it is found that the catheter can be advanced, so that the balloon is within the occlusion, more easily than has heretofore been found. It is then found that the occlusion may be widened by much lower balloon pressures than has previously been the case.
In the method of using the apparatus, the drive unit is generally only operated until the wire has passed through the occlusion. Nevertheless the further advantages, of easier subsequent catheter advancement, and easier widening of the occlusion, are, most surprisingly, still found. As yet we have no theory to explain why this should be so.
Preferably, the drive unit vibrates, preferably reciprocates, the proximal end of the wire at a frequency in the range 30-1,000 Hz. Preferably it can vibrate, preferably reciprocate, the wire at a frequency in the range 50-1000 Hz, more preferably 50-500 Hz. Preferably sub-ranges may be 100-500 Hz, and, for cardiac work, 200-400 Hz. Preferably, the drive unit is adjustable, to vibrate, preferably reciprocate, the proximal end of the wire at a frequency to be selected.
Preferably the vibration applied to the wire is a reciprocation, and the drive unit reciprocates the proximal end of the wire by a stroke in the range 0.1-5 mm, for example 1-5 mm, preferably 2-4 mm, or 0.1-1 mm, preferably 0.2-0.5 mm. This too may be adjustable.
The drive unit may comprise electric motor, or an air driven motor, or a solenoid.
Preferably the apparatus comprises means for adjustably clamping the wire, preferably comprising spring loaded quick release means.
The apparatus may comprise means for adjusting the force with which the wire is accelerated. To this end the wire may be spring loaded and the spring force may be varied. In one embodiment the drive unit operates to draw back the wire, against the spring force. The wire is then released to be driven forward by the spring force. In another embodiment the drive unit drives the wire forward and the spring force urges the wire backward.
The apparatus may comprise means for vibrating, preferably reciprocating, the catheter. Such means may be similar means to those described above with reference to the wire. In use the catheter may thus be vibrated, preferably reciprocated, in order to facilitate its passage through an occlusion that has already been passed by a wire. Whilst the catheter is thus vibrated the wire may be fixed. In other embodiments the wire may still be vibrated, the wire and the catheter thus being simultaneously vibrated, either by the same mechanism, or by different mechanisms, whereby the vibration/reciprocation characteristics--stroke, frequency, force etc--may be different, for the wire and the catheter.
Preferably, the apparatus has means for clamping the catheter. Suitably the apparatus comprises means for nonadjustably clamping the catheter. The catheter may have a collar at its proximal end and the apparatus may then have quick release means for clamping the collar.
The two clamping means may be adjustably spaced apart in some embodiments.
Preferably the apparatus comprises a housing carrying the said clamping means, and containing the drive unit, and any control means whereby adjustment of the operating conditions, as described above, may be effected. The housing may be suitable for hand-held use. Preferably, the housing is pistol-shaped, the wire and catheter being axially aligned with respect to the barrel. Suitably the means for clamping the catheter is located at the free end of the barrel. Suitably the apparatus is such that the wire can extend right through the barrel and be fed into a patient by progressively advancing it through the barrel, until it reaches the occlusion. It can then be clamped and vibrated, preferably reciprocated, and its advance is accompanied by an advance of the entire apparatus. The barrel may be removable to allow for cleaning and interchangeable to allow for different catheters to be fitted to the apparatus. There may be provided a kit comprising a butt portion housing the drive unit and a plurality of alternate barrels securable thereto, adapted to take different catheters.
Preferably, the wire is at least one metre in length, measured from the drive unit. The characteristics of the wire are thought to be important. It is not desired to employ a wire which produces a ramming motion at its distal end. Rather, it is desired to employ a wire which can produce a diffuse movement in three dimensions at its distal end. Preferably at least the distal end region of the wire end region of the wire is "floppy".
If one considers a catheter and wire held horizontally, with the distal end region projecting from the catheter, we would consider the distal end region to be "floppy", and suitable for use in the present invention, if it was unable to stay straight under its own weight, but rather bowed or drooped downwards, when it projected 10 cm or less beyond the end of the catheter. A particularly preferred "floppy" wire would have a distal end which bowed or drooped downwards when thus projected 5 cm or less, preferably 3 cm or less, beyond the end of the catheter.
The distal end region of a wire may be suitably "floppy" because of the type of material selected and/or because of the thin gauge of wire selected, and/or because of the construction of the wire. One suitable type of wire is a normal cylindrical angioplasty wire of thin gauge. Such a wire may have, at least at its distal end, but preferably throughout, a diameter in the range 0.11 mm, preferably 0.2-12 mm (preferably 0.25-0.9 mm, most preferably 0.25-0.6 mm, for coronary and tibial arterial procedures; and preferably 0.6-0.9 mm for other arterial procedures).
Another suitable wire has a distal end region which is of coiled construction. Unlike some wires intended for a ramming motion the coiled end region does not surround a core wire, which would make the distal end region rigid.
Preferably, the distal tip of the wire is smooth. It may be bulbous, and if so preferably has a diameter, or mean diameter, measured in the transverse direction, in the range 0.5-1.5 mm, most preferably 0.8-1.2 mm. It may be spherical but most preferably it is of ovoid or olive-shaped. Alternatively it may be of simple rounded-off form.
It is preferred that the wire, at least at its distal end region but preferably throughout, is a low-friction "slippy" wire. Such wire will be familiar to those skilled in the art. A suitable low-friction wire may have a microscopically smooth surface achieved by polishing, or may be coated with a low-friction material. Some such coatings are known as hydrophilic coatings.
Preferably, the bore or lumen of the catheter is slightly oversized, relative to the wire. Preferably the diameter of the lumen or bore is larger than the diameter of the wire by about 10-50%, preferably by about 20-40%.
The invention extends to a kit of parts for assembling an apparatus as defined above, such assembly generally being effected immediately prior to, or during, a procedure, and to a method of using apparatus as defined above, the method also being as described herein. The method may be used in angioplasty for any occluded vessel, but preferably is used in coronary angioplasty.
In accordance with a further, independent, aspect of the present invention there is provided apparatus for use in angioplasty, comprising a pistol-shaped unit, preferably suitable to be held in the hand, which is coupled, in use, to elongate means introduced into blood vessels of a patient during angioplasty.
The invention will now be further described, by reference to the accompanying drawings, which show, in schematic form, by way of example only, two embodiments of the present invention, as follows:
FIG. 1 is a first embodiment;
FIG. 2 is a side elevation of a second embodiment;
FIG. 3 is a cross-section view thereof;
FIG. 4 is an elevation from the butt end;
FIG. 5 is an end elevation from the opposite end to FIG. 4;
FIG. 6 is a view from above;
FIG. 7 is a view from below; and
FIG. 8 is a side elevation, showing the opposite side to that shown in FIG. 4.
In the drawings of the second embodiment, FIGS. 2 and 3 show a catheter and wire in place, whilst FIGS. 4 to 8 do not.
As shown in FIG. 1, angioplasty apparatus comprises, as is conventional, a balloon catheter 2, having an annular expandable balloon chamber 4 at its distal end; and a narrow-gauge, "floppy" wire 6, passing through the catheter, such that its distal end extends beyond the catheter. The tip 7 of the wire is olive-shaped in this particular embodiment.
At their proximal ends the catheter and wire are connected to a drive unit 8. The drive unit 8 has a housing within which is located an electric or air motor and a drive train to impart reciprocating motion to a clamping block 10 within which the proximal end of the wire is releasably clamped. In front of the block 10, and in alignment with it, is a clamping block 12 which releasably clamps the catheter 2.
The details of the motor and drive train need not be discussed here as these are well within the compass of the person skilled in the art. It is sufficient to state that the reciprocating stroke of the block 10 is adjustable, as is the frequency of reciprocation. These are respectively adjusted by dials 14, 16.
The housing for the drive unit 8 is small enough to be held in the hand.
The clamping block 12 of the catheter is adjustably mounted on a track (not shown) so that the spacing between the blocks 10 and 12 is adjustable, between about 10 and 40 mm (measured between the clamping positions).
In this embodiment, the diameter of the wire 6 is about 0.4-0.45 mm, and the transverse diameter of the olive-shaped tip is about 1 mm. The wire bows under its own weight when projected about 3 cm or more beyond the end of the catheter. At a projected length of 5 cm the tip of the wire droops down by at least 1 cm, with the rest of the wire and the catheter held horizontally. The diameter of the catheter is about 1 mm and the balloon is expandable to a diameter of about 3 mm. The frequency with which the guide wire can be reciprocated by the drive unit may be adjusted to any frequency between 50 and 500 Hz. 200-300 Hz is thought to be most effective for most conditions, but lower frequencies, such as 60 and 120 Hz have been known to be effective, provided a sufficiently "floppy" wire is used. The diameter of the bore of the catheter is about 0.6-0.65 mm. The reciprocation stroke of the wire is adjustable between 0.1 and 5 mm. 0.2-2 mm is thought to be most effective, for most conditions, with this embodiment.
The clamps associated with the blocks 10, 12 may be of any form. Conveniently the clamp for the wire may be a diaphragm clamp, the diaphragm being pressed down on to the wire by a screw. This is known as the Tuoey-borst system. The block 12 may comprise a slot to receive the catheter, and an adjustable strap extending over the catheter and the block. By means of such clamps a single apparatus is suitable for procedures which may involve a wide range of wire and catheter sizes.
In an angioplasty procedure, the guide wire is introduced into the body via the femoral artery and is guided into place up to the occlusion shown as 20. If the catheter has not already been located on the guide wire, it is now fed along it until its end is close to the tip of the guide wire--generally between 10 and 30 cm from it. The guide wire and catheter are then clamped in place. The unit is then switched on and the frequency and reciprocation stroke adjusted as required. As the guide wire advances through the occlusion the drive unit can be advanced but preliminary observations indicate that it may be better to position the drive unit in a fixed location and to progressively advance the guide wire, by successively releasing and re-clamping it, whilst leaving the catheter clamped in the same position throughout.
Preliminary trials have indicated that the wire advances easily through the occlusion and no propensity for it to deviate from vessel, or pass along the wall of the vessel, has been observed. It has been found to substantially ease the subsequent advancement of the catheter so that the balloon is located within the occlusion. Moreover, most surprisingly, it has been found that the required expansion of the balloon 4 can be effected at very much lower pressures than has previously been the case. For example, in a procedure which would have normally required an expansion pressure of about 12 atmospheres, an expansion pressure of 2-3 atmospheres has been employed, using the method and apparatus of the invention.
In the second embodiment the apparatus is pistol-shaped, and sized to fit in the hand of the operative, typically a cardiologist.
The apparatus comprises a barrel 22 having an axis with which the wire 24 and catheter 26 are aligned. It also comprises a butt portion 28 within which is located a drive unit 30 and battery power supply 32, accessible by means of a removable wall portion 33. Externally the butt portion carries a dial 34 by means of which the frequency of reciprocation is controlled.
The catheter terminates, at its proximal end, in a collar 36, and this collar is clamped within a recess 37 at the free end of the barrel 22. It is clamped therein by retracting a clamping block 38, controlled by an externally projecting, ridged moulding 40, and is spring loaded by means of spring 42 located within the barrel.
The wire is clamped within the barrel under the control of an externally projecting clamping knob 44, arranged transversely to the barrel 22. Beneath the clamping knob, not shown, is a helical spring. Pushing the clamping knob, against the spring force, moves an aperture into alignment with a second aperture for the wire, so that the wire can be freely fed through both apertures. Releasing the clamping knob moves those apertures out of alignment, so that the wire is clamped therebetween. When the drive unit is operated, the knob 44 is reciprocated, and thus the wire is reciprocated.
At the butt end of the barrel a reciprocation control knob 46 is located, being adjustably screw threaded within a threaded bore at the butt end. The control knob 46 has a central aperture 48 through which the wire 24 may freely move. Retained in compression between the control knob and the clamping knob 44 is a helical spring 50. The position of the control knob 46 controls the compression of the spring 50. The drive unit operates to pull back the clamping knob 44 and wire 24, thus loading the spring 50. The clamping knob is then released and the spring force urges the clamping knob and wire forwards. In this embodiment the stroke is 0.3 mm.
The operation of the drive unit is under the control of a trigger button 52.
To use the device shown in FIGS. 2 to 8, the catheter 26 is normally introduced first. If it passes through an occlusion, the apparatus need not be used. However, if it cannot pass through the occlusion the wire is fed, inside the catheter, up to the occlusion. The apparatus shown in the drawings may have been located on the wire prior to it being moved within the catheter, or after this. Once the wire is clamped the apparatus may be used to reciprocate the wire, and thereby help it to pass through the occlusion. Once it has passed through the occlusion the catheter should be able to advance, so that the balloon portion is located in place, to expand.
The wire 24 in the second embodiment is a "floppy" low-friction hydrophilic coated wire of 0.25 mm diameter and has a floppy coiled distal end region 5 cm in length. The distal end region bows under its own weight when projected about 5 cm beyond the end of the catheter. The distal tip is of simple rounded-off (non-bulbous) form.
In a third embodiment (not shown) the apparatus is again pistol-shaped but the catheter is not secured to the barrel by means of a spring-loaded clamp 38. Rather, the catheter hub is held by a "twist-lock" or bayonet-type fitting. Furthermore, there is no reciprocation adjustment in this embodiment, and so no reciprocation control knob 46 or reciprocation control spring 50 is required. The stroke is fixed at 0.2 mm. The wire is held in a quick release vice grip. The barrel 22 is removable from the butt portion, by unscrewing it. A plurality of barrels is provided, able to secure different types and sizes of catheter.
The reader's attention is directed to all papers and documents which are filed concurrently with or previous to this specification in connection with this application and which are open to public inspection with this specification, and the contents of all such papers and documents are incorporated herein by reference.
All of the features disclosed in this specification (including any accompanying claims, abstract and drawings), and/or all of the steps of any method or process so disclosed, may be combined in any combination, except combinations where at least some of such features and/or steps are mutually exclusive.
Each feature disclosed in this specification (including any accompanying claims, abstract and drawings), may be replaced by alternative features serving the same, equivalent or similar purpose, unless expressly stated otherwise. Thus, unless expressly stated otherwise, each feature disclosed is one example only of a generic series of equivalent or similar features.
The invention is not restricted to the details of the foregoing embodiment(s). The invention extends to any novel one, or any novel combination, of the features disclosed in this specification (including any accompanying claims, abstract and drawings), or to any novel one, or any novel combination, of the steps of any method or process so disclosed.
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|U.S. Classification
|International Classification
|Cooperative Classification
|European Classification
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Owner name: MEDICAL MIRACLE COMPANY LIMITED, GREAT BRITAIN
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:REES, MICHAEL RALPH;REEL/FRAME:009090/0668
Effective date: 19951114
Owner name: MEDICAL MIRACLES COMPANY LIMITED, GREAT BRITAIN
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:REES, MICHAEL RALPH;REEL/FRAME:007965/0736
Effective date: 19951114
|Mar 26, 1998
Owner name: MEDICAL MIRALE COMPANY LIMITED, GREAT BRITAIN
Free format text: ;ASSIGNOR:REES, MICHAEL RALPH;REEL/FRAME:009082/0988
Effective date: 19951114
|Dec 29, 2001
|Fee payment
Year of fee payment: 4
|Jan 6, 2006
|Fee payment
Year of fee payment: 8
|Feb 8, 2010
|Maintenance fee reminder mailed
|Jul 7, 2010
|Lapse for failure to pay maintenance fees
|Aug 24, 2010
|Expired due to failure to pay maintenance fee
Effective date: 20100707


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Sales & Support Mon-Fri. 10am - 6pm PST
CAP Photocontroller "Night", PTC-2
The PTC series of Day/Night Controllers by Custom Automated Products are perfect when you need to turn a device on only during daylight hours or only at night. A photocell senses whether it is day or night, and turns the device plugged into it on or off depending on which model you are using. The PTC-1 turns on whatever is plugged into it during the day when the lights are on. The PTC-2 turns on the device during the night, when the lights are off. PTC controllers are rated for 15 amps @ 120 volts. 3 year warranty.
Want to order by phone? or Not sure where to start? Don't Worry, give Monster Gardens a call at 1-707-588-8844 and we will be happy to point you in the right direction!
©2010 Monster Gardens - Seattle, WA - Rohnert Park, CA - New York, NY

subset: commoncrawl


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What is SQL injection attack?
A SQL injection attack is a way of inserting or injecting a sql query via the input data from the client side of an application/website so as to make a sql query function differently from it intended purpose and cause sql database to perform differently from it intended purpose by an attacker.
Example of an sql attack is describe in the picture below;
The intended query should look like "select * from users where user_id = 'myusername' and password = 'mypassword' limit 1 " but for an attack, the input fed to the sql will be one that can cause trouble, though sql will see it as a valid query. Example is "select * from users where user_id=" OR 1 = 1;/*' and password = '*/–' ". What this query does is that even though there is no username with empty ", the application will run true and the attacker will gain access to the website or application to cause further damages.
So, to avoid this problem, I will be showing one way to prevent sql injection using php-mysql approach in this tutorials. See steps below:
-> Assuming you will be receiving inputs from users such as username or password, topic, category and other kinds of input, expect that there could be attack, so, write code that will prevent it.
I will be using php prepared statement to prevent this attack. In php-sql prepared statement, the input from users is not communicating with the database directly. So, any inputs from user is treated as mere string.
The example below shows a php function to check if login exist and respond accordingly using php prepared statement.
public function check2login($username, $password) { $conn = $this->connect(); $stmt1 = "select username, password from user_table where (username = ? and password = ?) limit 1"; $prep1 = $conn->prepare($stmt1);//prepare the statement. $prep1->bind_param('ss', $username, $password);//;//bind each variable to expected character to be received $prep1->execute();//execute command. $prep1->store_result();//store results. if($prep1->num_rows == 1){ echo 'y';//login success } else echo 'n';//failed login, not exist probably. $prep1->close(); $this->closeConn(); }
In the code snippet above, irrespective of whatever the user sends, the sql command first run, create a result pool, then compares it with whatever the user sent. So, there is no way user can inject dangerous sql code to cause trouble and your app is save from trouble.
If there are any contributions, or issues, or explanations, you can use the comment section or email @NaijaTech
See Post on app that talks to the internet via php, mysql technology


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W'S Printed Twill Over Shirt
W'S Printed Twill Over Shirt
€ 255,00
The model is 179 cm/5'10" tall and wears size S
Additional Information
Product Info
Item No.: WWCAM0631-PT04-3983
A long, flowing shirt in printed twill, featuring a classic shirt collar. Easy to wear, it's perfect over skinny trousers.
Free Shipping and Return
- Free Standard Shipping
- Free Returns
- 30 days to try our items at home and decide if you want to return


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Are you fond of sexy teens with big sexual appetite? Step in and meet Marina, a generous blonde who´s a great company. The slutty bitch has a slim tanned body and small tits and enjoys showing off her lovely firm butt in front of the camera. Watch her blowing a big dick sitting on knees. Enjoy!
- dtr76ed
- : 6min 59sec
- : 5 May 2014
- Exclusive video


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Billy Gray
Billy arrived in Hanoi in November 2015 with the intention of staying for just six months. He didn't expect that flights to leave would be so expensive, so decided instead to stay and write for the Word.
Organic Hanoi
Tracing where food comes from is becoming easier, but it's not 100% fail-safe. Billy Gray gives us the lowdown on organic food certification and a list of outlets and suppliers that you can trust.
Casa Italia
Located in the former residence of the Italian ambassador, in the heart of Hanoi's French quarter, Casa Italia is as authentic Italian food as you'll find in the capital.
Playboy Establishment
The place to be seen with the hippest crowd in town, where Hefner's playboy lifestyle is in full swing, Playboy Establishment is doing its best to redefine the boundaries of the so- called conservative city of Hanoi.
School of Mosh Festival
Metalheads, hip-hop fiends and graffiti artists get ready. This one's for you
Kem Dua
It's the summer. It's hot. So what better way to cool you down than a Vietnamese favourite — coconut ice-cream?


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View All Ruger 10 22 Accessories »
View All Ruger 10 22 Accessories Tactical »
View All Ammunition »
Price shopping for Ruger 10 22 Accessories? Brownells.com carries the widest selection at the best prices on the web. Our selection of 383 Ruger 10 22 Accessories and Ruger 10 22 Accessories Tactical represents the best of the best, on sale at prices from $1.99 to $149.99. As the number one online retailer of gun parts and gunsmith tools we are able to provide excellent customer service, great prices, and top quality merchandise, every day. We're so confident in our selection of Ruger 10 22 Accessories, we make you a promise. Our 100% satisfaction guarantee means if you're not completely happy with your purchase, we'll do everything we can to make it right. Shop our inventory of Ruger 10 22 Accessories and place your order on the web or over the phone. We're here to provide you with all the gun parts and gunsmith tools and information you need, so - if you don't find what you're looking for online - give us a call!


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'Real living wage' to be central to Labour 'bargain in the workplace'
A Labour government would enshrine in law a "real living wage" expected to be more than £10 an hour, shadow chancellor John McDonnell has announced.
Mr McDonnell said Labour would create a living wage review body with a remit to ensure that the minimum income is set at the level needed for a decent life, which he said was likely to be higher in 2020 than the £10 level he proposed last year.
The announcement came in a keynote speech to Labour's annual conference in Liverpool, in which he promised an "interventionist government" which would use a £250 billion national investment bank to support British industry and create a "manufacturing renaissance" following withdrawal from the EU.
He won applause by promising a shake up of company law to prevent abuses of the kind which former BHS boss Sir Philip Green has been accused of, telling the conference: "U nder Labour there will be no more Philip Greens at all."
He won a standing ovation as he concluded his speech by saying that Labour had a "vision to rebuild and transform Britain", adding: "I n this party you no longer have to whisper its name, it's called Socialism."
After the bruising leadership contest over the summer, Mr McDonnell held out an olive branch to defeated candidate Owen Smith, praising his efforts to block government benefit changes. And he also name-checked prominent moderate Caroline Flint.
Announcing his plans to improve on the current £7.20 rate of the National Living Wage, Mr McDonnell said: "When we win the next election we will write a real living wage into law.
"We'll charge a new living wage review body with the task of setting it at the level needed for a decent life. Independent forecasts suggest that this will be over £10 per hour.
"This will be a fundamental part of our new bargain in the workplace...
"Backed up by our commitment to investment, we will end the scourge of poverty pay.
"Decent pay is not just fundamentally right, it's good for business, it's good for employees, and it's good for Britain."
Mr McDonnell said Labour would be putting forward proposals to help businesses - particularly small and medium-sized companies - implement the higher living wage.
And he indicated that this could involve state support via an extension of National Insurance breaks for employers under the Employment Allowance.
"We will be examining a number of ideas, including the expansion and reform of Employment Allowance, to make sure that this historic step forward in improving the living standards of the poorest paid does not impact on hours or employment," he said.
The shadow chancellor also said Labour would reintroduce sectoral collective bargaining across the economy to end a "race to the bottom" on wages. And he restated his commitment to repeal the Trade Union Act which restricts striking rights.
More resources for HM Revenue and Customs and the Gangmasters and Labour Abuse Authority would ensure there were "no more national scandals like Mike Ashley of Sports Direct", he said.
The living wage proposal was warmly welcomed by trade unionists, including Unite general secretary Len McCluskey, who described it as " music to the ears of the millions of low-paid workers who are getting poorer under this Government".
Dismissing the Government's National Living Wage as "a con", Mr McCluskey said: "We have to get back to a situation where a fair day's work is respected with a fair day's pay.
"The people who keep our economy moving, care for our elderly, sick and our children, clean our streets, serve in our shops - the millions of people who are the backbone of our nation - are paid enough to enjoy the decent life they deserve."
Brian Rye, acting general secretary of the building workers' union Ucatt, said: "This is a genuinely radical policy which will end the low-pay misery experienced by thousands of workers including many in construction when, despite working long hours, they still don't earn enough in order to properly live."
And Manuel Cortes, general secretary of the TSSA transport union, hailed it as " a bold and grown-up approach to lift workers out of in-work poverty".
"For too long British workers have had their wages and standards of living kept artificially low by Tory governments who have been subsidising bosses by paying out tax credits to those in who are in work rather than make work pay properly," said Mr Cortes.
"This policy delivers more than long overdue wage justice; it delivers for the whole economy as more workers will be taken into the tax system rather than out of it and, with more money in their pockets so people will be able to spend more."
Mr McDonnell confirmed his ambition to shake up the tax system to shift the burden "away from those who earn wages and salaries and on to those who hold wealth". And he said he was "interested in the potential of a universal basic income".
Setting out his plans for more state intervention in industry, he said: "We need a new deal across our whole economy, because whatever we do in Britain, the old rules of the global economy are being rewritten for us.
"The winds of globalisation are blowing in a different direction.They are blowing against the belief in the free market and in favour of intervention.
"Good business doesn't need no government. Good business needs good government. And the best governments today, right across the world, recognise that they need to support their economies because the way the world works is changing."
He accused the Conservatives of being "too blinkered by ideology" to act promptly to protect industries like steel against global market pressures.
Employers gave a wary response to the shadow chancellor's proposals.
Terry Scuoler, chief executive of the manufacturers' organisation EEF, said: "At last both Government and Opposition are talking in depth about the importance of industrial strategy and how manufacturing must be at the heart of driving growth and infrastructure investment at regional and national level.
"Business will need to be convinced, however, that some of the proposed policies are relevant for a modern economy. In particular, a return to collective bargaining is a backward step."
And Adam Marshall, acting director-general of the British Chambers of Commerce, said: " John McDonnell talks of an 'interventionist' future Labour government, but needs to remember that there's both good intervention and bad intervention. Good intervention creates the conditions for all businesses to thrive, but bad intervention ensnares them in red tape and makes them less inclined to employ, train or invest.
"As the Labour Party develops its alternative economic proposals, it must remember that the state cannot control every aspect of economic or business life and stay competitive in a global economy."
Mike Cherry, national chairman at the Federation of Small Businesses, welcomed the proposal to expand the Employment Allowance, adding: " Our members will also be pleased by moves to create new small business workspaces in local communities, strengthen small business access to finance to enable them to grow, shake up the energy market to allow small local suppliers to compete and innovate, and bring greater parity between how the welfare system treats the self-employed and the employed."
Meanwhile, Rebecca Long-Bailey, shadow chief secretary to the Treasury, said Labour would fight to make the UK economy work for everyone.
She said: "My mum has a little saying: 'Back us into a corner at your peril'. We will always come out fighting and we are fighting - fighting to make our economy great, to make our economy fair and to make our industry the envy of the world.
"At the heart of this is making sure that the prosperity we generate reaches every corner of this country so that no community is ever left behind again."
CBI director-general Carolyn Fairbairn said businesses would be "wary" of Mr McDonnell's "combative tone ... and a focus on extensive intervention".
" The best way to increase pay and living standards across the UK is to support firms to improve productivity," she said. "We already have an expert independent Low Pay Commission, which should have responsibility for setting statutory wages levels."
Mark Littlewood, director-general of the free-market Institute of Economic Affairs think-tank, dismissed Mr McDonnell's interventionist plans as "fantasy economics".
"The shadow chancellor wants a return to the industrial strategy of the 1970s, ignoring the past failures of a raft of initiatives, from subsidising the nuclear industry to Concorde," he said.
"It's time for the shadow chancellor to get real. The long-term economic prosperity of the UK will not be secured by shifting taxation to wealth, by higher spending or by more regulation. Labour's strategy amounts to huge private sector 'austerity' in order to protect and expand the public sector. This would be disastrous for the health of the UK economy."
Chairman of the GMB union's young members' section David Hamblin said Mr McDonnell's real living wage should be extended to under-25s, who are currently excluded from the National Living Wage and entitled only to minimum wage levels varying from £3.30 to £6.70 an hour.
"Equal work for equal pay is an absolute must and so the inequality of the current living wage for under-25s cannot be ignored," he said. "For a young person, the food in their mouth and the roof over their head is no cheaper due to their age."


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The chocolate-maker has secured the backing of new owner Kraft for a series of branded offering afternoon tea and an on-site chocolatier service, making large versions of popular bars such as Curly Wurlys and Flakes.
As many as 60 outlets could be opened over the next three to five years as part of a 20-year licence deal with a group of retail entrepreneurs who would lead the venture.
Cadbury signed an agreement with the team, including David Morris, the former director of food and restaurants at Harrod, before US-based Kraft completed its £11.5bn takeover of the company in February.
Kraft has now given the plans the go-ahead, although it is not providing financial backing.
Cadbury said it was "very early days" for an "exciting concept that builds on the success of the Cadbury brand".
The scheme could build on the Cadbury Cocoa House name. Cadbury operated an outlet of that name in Bath – primarily as a marketing tool – until 2007.
Mr Morris is expected to become chief executive of the venture, with retail entrepreneur Marilyn Newman as chairman.


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So it just hit me the other day that it's my 6th year anniversary on this blog. I guess I've been so busy filming my webseries, The Adjuncts, that I completely forgot! I would love to go into the whole what I've learned in the past six years but it boils down to one sentence, life is challenging so make the best out of it and love God. The end. Let's move on.
So in the news, we're discussing more Kardashian shenanigans, people want to save a gorilla over a child and other people still are getting fired over some racist bullshit on Facebook? Can we just pause for a minute and look at the headlines? Why does fuckary continue to lead our conversations? One answer, because it's entertaining, stupid and it's getting hot outside.
Since I have to prep for two 16 hour shoots this weekend, I'll make this quick. It's going to be a hot summer and I'm excited to start blogging about the foolery out there. I'm also excited to share with you my 31 things I'm doing this summer to make it fabulous. I'm turning 32 in the fall and I want to take 31 out with a bang.
Kisses! See you Monday!
-Boujie Mack


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Wine Details
Wine Description
(2013 Vintage) Ornellaia, Tenuta dell'Ornellaia's flagship wine, was first produced with vintage 1985, from an extremely careful selection of the vineyards grown on the Estate. Produced in limited quantities, hand-crafted and vinified with the utmost care and attention to detail, Ornellaia has constantly received top ratings from the most influential opinion leaders around the world. Vintage 2005 marked the 20th anniversary of Ornellaia which was celebrated with numerous events all over the globe and with the creation of special anniversary large size bottles.
Wine Buyer(2006 Vintage) The main characteristic of Ornellaia 2006 is without a doubt its lush depth and a-exuberancea (aLaEsuberanzaa). Here is apowerful, concentrated wine whose intensity is immediately obvious. Its complex, rich bouquet is complemented bysweet, dense-packed tannins and a lively acidity, and all of its components are in admirable harmony creating a veryelegant wine.
Wine Spectator(2013 Vintage) Vanilla, toast and smoke notes shade the black cherry and plum aromas, while the spicy oak theme carries over on the palate. Shows fine balance. Best from 2018 through 2029.-B.S.
James Suckling(2013 Vintage) Amazing graphite and violet aromas with dark fruits. Medium to full body, ultra-velvety tannins and a long and beautiful finish. Formed and tight. I love the fresh ginger underneath it all. A cool profile that's so approachable with wonderful length. #84 Top 100 of 2016
Wine Enthusiast(2013 Vintage) A blend of 45% Cabernet Sauvignon, 38% Merlot, 10% Cabernet Franc and 7% Petit Verdot, this opens with aromas of red currant, fragrant purple flower and exotic spice. The currant aroma carries over to the austere palate along with cranberry, chopped herb and French oak. With its backbone of firm acidity and assertive close-grained tannins, it already boasts finesse but will need years to soften and develop. Drink 2021-2028.
Robert Parker(2011 Vintage) Rating: 94/100 - As reviewed by Robert Parker on 10/21/2014


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An Introduction of Aperture Coupled Microstrip Slot Antenna
A microstrip slot antenna is very small and lightweight still it has the problem of back radiation due to which power loss occurs and the SAR increases. To reduce the back lobe a technique introduces, i.e., aperture coupled microstrip slot antenna which reduces the back lobe as well as increases the bandwidth of the antenna. Aperture coupled microstrip slot antenna couples the patch antenna with micro-stripline through an aperture. At microwave and millimeter wave frequencies microstrip slot antenna becomes very small & lightweight. In spite of these advantages, it has main disadvantage of back radiation; which limits its use in mobile communication. To minimize the back radiation a reflector plate behind the slot or a cavity (2-3) may be used.


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Value of Purdue degree?
Purdue ranked 87th in the Times Higher Education - QS World University Rankings released in October, a 12-place increase for Purdue.
In January 2009, two surveys ranked Purdue among the best in the nation in terms of academic value:
SmartMoney magazine ranked Purdue ninth nationally in its "payback" survey, which was designed to quantify the long-term value of a college education. The survey compared tuition costs with graduates' earning power to determine the rankings. We were amongst only two Big Ten universities to make the magazine's top ten.
Purdue also made the list of the 100 "best value" colleges published by Princeton Review, which said that Purdue was a "relatively inexpensive state school with a reputation rivaling the world's best institutions of higher learning …"
According to the College Board's 2007 study "Education Pays," those with a bachelor's degree will earn over 60% more — or more than $800,000 over a lifetime — than someone with only a high school diploma.


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[huhs; Czech hoo s] /hʌs; Czech hʊs/
John, 1369?–1415, Czech religious reformer and martyr.
the flesh of the European dogfish, when used as food
John, Czech name Jan Hus. ?1372–1415, Bohemian religious reformer. Influenced by Wycliffe, he anticipated the Reformation in denouncing doctrines and abuses of the Church. His death at the stake precipitated the Hussite wars in Bohemia and Moravia
Tagged: h
Read Also:
- Hussain
/hʊˈseɪn/ noun 1. Nasser (ˈnæsə). born 1968, British cricketer born in India; played in 96 test matches for England (1990–2004), 56 as captain
- Hussar
[hoo-zahr] /hʊˈzɑr/ noun 1. (originally) one of a body of Hungarian light cavalry formed during the 15th century. 2. a member of a class of similar troops, usually with striking or flamboyant uniforms, in European armies. /hʊˈzɑː/ noun 1. 2. a Hungarian horseman of the 15th century n. 1530s, from German Husar, from Hungarian huszár […]
- Hussein ala
[ah-lah] /ˈɑ lɑ/ noun 1. Hussein [hoo-seyn] /hʊˈseɪn/ (Show IPA), 1888–1964, Iranian statesman and diplomat: premier in 1951 and from 1955 to 1957. /ˈeɪlə/ noun (pl) alae (ˈeɪliː) 1. (zoology) a wing or flat winglike process or structure, such as a part of some bones and cartilages 2. (botany) a winglike part, such as one […]
- Hussein I
noun 1. 1935–1999, king of Jordan 1953–99.


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Jul 08, 2013 - Independent iOS app developer Artem Kantalinskiy introduces Potsy 1.0, his addictive new arcade game for iPhone, iPad and iPod touch. An old and rarely used name of the game Hopscotch, Potsy is simple and fun tap entertainment based on one the most popular worldwide playground game. Now you can use your fingers! Players hop or jump through the right angled spaces outlined on the ground. Featuring 16 training levels with visual instructions, Potsy is played in 4 Seasons with 80 unique levels.
Feb 08, 2012 - iOS app developer Artem Kantalinskiy introduces Dualis 1.0, his addictive time killer game for iOS devices. Based on the original "Numbers", Dualis offers the best example of the popular board game. The goal is to remove all numbers from the original list. Remove the last number in a row and the first number in the next row if they are the same, or give 10 in sum. Simple to understand and play, Dualis features three gaming modes, a steps history as well as results and a hints system.


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Venture Development Corporation (VDC) recently released their Embedded/Real-time and Mobile Application Operating Systems study. According to VDC, the overall embedded software code base is growing at a rate of approximately 9% per year. VDC concludes that system complexity is driving the need for greater amounts of software content per project. VDC expects projects using commercial and open source operating systems to represent the bulk of total embedded software code base growth going forward. In addition, VDC's findings suggest that engineers working on projects using commercial, open source, and in-house operating systems, as well as those using no formal operating system (running on their target system), to employ significantly greater amounts of software code on their next embedded design.
According to VDC, customers evaluating embedded operating systems are seeking to satisfy a growing list of specific product requirements – and that vendors without adequate offerings in these areas are often not considered as part of a more thorough evaluation. Solutions supporting more complex system user interfaces and communication stacks such as USB connectivity, TCP/IP, and wireless communication protocols are currently in high demand within a majority of projects. Most vendors have therefore either built these solutions in-house to complement their offerings or satisfied these through partnerships in order to fill gaps within their offerings. These market factors are quickly turning operating system vendors into software stack platform providers.
Software Sources
- Code leveraged from previous designs
- Commercial software solutions
- Using open source solutions
- Code developed in-house using more efficient tools or larger engineering teams
- Code generation technologies
More info: VDC


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The Clemson Tigers are maintaining their lead on Union defensive tackle Rashaad Jackson (6-2, 265, 4.9) heading into the second week of August. Clemson linebackers coach David Blackwell extended a...
Premium Content
Subscribe today to read the full article and get everything Rivals has to offer.
- Member-only message boards
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- Exclusive coverage of Rivals Camp Series
- Breaking recruiting news


text:
A Prospective Study Examining the Barriers to Care for Harris County Cervical Cancer Patients
This study is ongoing, but not recruiting participants.
M.D. Anderson Cancer Center
ClinicalTrials.gov Identifier:
First Posted: August 22, 2007
Last Update Posted: June 20, 2017
Information provided by (Responsible Party):
M.D. Anderson Cancer Center
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
No Study Results Posted on ClinicalTrials.gov for this Study
|Study Status:
|This study is ongoing, but not recruiting participants.
|Estimated Study Completion Date:
|July 2019
|Estimated Primary Completion Date:
|July 2019 (Final data collection date for primary outcome measure)


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Posted on: 08-25-2012 - Updated on: 02-01-2014 - viewed 31717 times
My all time favorite macro on my warrior for PVP. Ever since they changed it so you don't have to stance dance, its so easy to reflect a Soulfire or Frostbolt – the best is to reflect Fear haha.
Not much to this macro, just mash it and reflect.
#showtooltip Spell Reflection /equipslot 16 Ruthless Gladiator's Slicer /equipslot 17 Ruthless Gladiator's Shield Wall /cast [equipped:Shields] Spell Reflection
#showtooltip Spell Reflection
/castsequence Spell Reflection,
This should work for you :P
any macro for a harlem shake?
#showtooltip boogiedown
/cast dance
/cast freeze
/cast base drop
/cast harlem shake
Casting this macro will cause many retarded clone videos to spawn on youtube. Use with caution


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White Hats /Fact Check #113
A Few Questions and Answers From The Top:
With the continuing assistance of the White Hats and their colleagues, we have been allowed to provide you with information directly from the front lines, unfettered and unvexed, as it travels a pure line to us.
I know the information is not always pleasant.
But, if you would prefer that we embellish it, or write for impact rather than fact checking, then we would be forced to throw away the very reason we reached out to the White Hats in the very beginning: To get to the truth.
In furtherance of that goal, we have been given answers to two questions, as of late.
Please read this information carefully.
Thank you for your continued readership. And thank you, again, to the White Hats and their colleagues and staff. Please await further information as it is available.
1) For quite a while, many of you have requested more clarification as to why we have been advised to act quickly in the exchanging of Dinar and Dong once the revalue has taken place. The following, from the top, goes deeper into the reasons for such a suggestion:
There is no plan as yet to organize Forex Markets, or any volume of demand to sustain the amounts of some issues. Printing has not been coordinated with bank capability to respond. Each sector is working for self interest.
The first trades will be Private Placements which will ONLY be advised after safe completion.
The banks will not have been pre-advised, and there will be a short window before chaos hits.
Once Guru sites get a hold of it, mass chaos may result with a tidal surge of desperate cases mass appearing. Banks will NOT be able to cope so it is open to question the likely moves, but historical evidence of Banks response is that of lock outs.
Private Rates may not be Public Rates, so when Public Supply grossly exceeds market needs, the market may respond by driving down Exchange rates. Or suspending trading.
For that reason, we will try to set up a special pre advised and timed Notice Release just for the 2 sites [OWoN and WHA], so you each have the lead time to get in and out fast before chaos hits. You have nothing to lose by being in and out first and fast.
You have everything to lose if caught up in the late Ambulance Chasing surge.
You all need to understand that the key parties Do Fully Understand the extreme importance this means to many of you, which is why they so carefully advise parties to take a step back after cashing out, to keep it safe, and only partially reinvest in what you know and can control.
Otherwise, it will be lost and game over. Life is NOT a game. It's brutal and can be ugly. People can make it so.
2) Many have asked about private trading platforms that were abused by Bush, the agencies and cabal. Although such was detailed in the WH reports, we have some additional information, as follows:
The White Hats and their London associates have been fighting this corruption together. Each have exposed numerous guilty parties. Only the power of their special link got it exposed at the very Top.
Many do not understand the sheer, enormous pressure they work under. Hours off the Richter scale and the Roller Coaster temperaments of dealing with Mercurial Third and First World personalities. Diplomacy is key with extensive knowledge, Cultural experience and intellect needed.
[WHA comment: Remember when I told you that the WH's are qualified for this work? Now you know why]
The White Hats, and other good US Patriots, have the one key contact needed who has the essential knowledge, experience and standing needed to assist them get those funds into their own Platform use for the true benefit of all. They do all work very closely together with huge integrity.
OWoN and the White Hats will be working closely together to trade those funds and get them into Project Investment and Job Creation. Also for good Humanitarian needs. {One World of Nations}
OWoN is not a currency trading or Guru site. It has already built up a substantial US and Global following and has clear intentions of using many US and Global supporters for Project development and delivery.
In addition Community Planning and development. Major opportunities for US and other nationals to help turn our world around.
Yes, the site is different, but it is challenging and uplifting consciousness to address the realities of our true Global problems and our collective need to both understand and plan for the rapid changes our nations are experiencing, with vast social ramifications.
They are both on and even behind the front lines in this fight for Justice and all of us. Your gain is their pain. They do this as Patriots. Contentious as that may be. But they have already built a network of willing multi national parties able to put those funds to good use for all of us and our planet.
They are very much on our side. Without them, all we are left with is Political chaos, incompetence, Bank /Cabal chicanery and subterfuge. Who else is giving you this information flow and help? Caring has a cost. One they pick up alone.
Fantastic , although I am normally an observer because when I piped up in the past about the truth , of the nature of the beast , for the past 40 years, I was shunned and now it's time to shine , and I will help anyway I can with in my way and means , and to pay it forward in as many oppurtunities as possible for the people
william wratten
3/29/2014 04:00:34 am
I want very much to help others and lm very sincere william wratten
3/29/2014 04:40:52 am
A big round of applause to all involved in your team to research, be connected to an inside source and to share with us! I pray Gods protection over all of you, but most of all pray we really all do our part when this blessing manifest. I thank God for allowing your team to have a true connection to share what's really enough to keep us lifted, but not too much to get you all disconnected! Thanks again, and may God continue to bless you.
joy oua
3/29/2014 04:52:02 am
Yes ! This is a great opportunity for all of us. Contributing small amounts ( 10.00 / 20.00 ) over my lifetime, to increase to really assist mankind is a dream come true. I can hardly wait to write the checks. For all you do, and have done, you are and have been so appreciated. Love and blessings to all.
3/29/2014 05:13:20 am
I would like to know more about the private placement programs and/or trade platforms/programs being offered. Many groups profess to be representing such opportunities, but I have been unable to see any of them to completion, due to one professed reason or another. I understand they take place only among a select group of individuals who understandably guard their anonymity with utmost diligence. Given these restrictions on disclosure, I would suggest one only attempt to participate in these programs if your funds remain exclusively under your control at all times, and are simply hypothecated against with no encumbrances or liens other than that you agree to allow them to be verified prior to trading only to conform to bank requirements. Otherwise, they should remain 100% under your control exclusively in your bank account at all times for the duration of the trading program(s). Do NOT allow your funds to be moved out of your account into another bank unless you can verify that you are sole signatory on the new account and that the new account is registered in your name only as well.
3/29/2014 09:54:37 am
Can someone explain what OWoN is? I have been involved with this most amazing situation/opportunity for 4 years, but have no idea what this site or group are? I would love to know more..
joy ous
3/29/2014 03:49:54 pm
One World Of Nations
3/29/2014 12:19:44 pm
I am an observer and learning about all that is involved. Thank you WH for all that you do. When this comes through, I plan on paying it forward to as many people as I can, especially our veterans.
Comments are closed.


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IT sector will Boost in 2 yrs ..
He told that the first wave of the IT sector arrived in Coimbatore with creation of infrastructure at various premises, including the Coimbatore Hi-Tech Infrastructure Private Limited (CHIL), Software Technology Parks of India facilities and Science and Technology Entrepreneurial Park. A number of independent companies had also started operations.
Software exports from Coimbatore now were about Rs. 550 crore and the figure would soon go up to Rs. 1,000 crore. However, this was relatively low as the other tier-two cities were already doing larger volumes.
The CHIL had created six lakh sq. ft of built-to-suit facilities at the Special Economic Zone. This could be scaled up to even 1.2 million sq. ft. It also had three anchor companies taking space at the built-to-suit campus. The annual exports from CHIL were about Rs. 100 crore now.
Growth in Coimbatore was likely to be more from the IT-enabled services segment. For companies in larger cities, moving over to Coimbatore would provide at least 20 per cent cost advantage.
"We were in dire need of infrastructure, especially for plug-and-play operations. When that is created, recession has set in," he pointed out.What was needed now was constant awareness about the potential here. Coimbatore should be promoted as an ideal location for IT and ITES companies.
The Government should expedite works on the Tidel park here, he said.


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The Cowboys are not running out of time when it comes to filling the needs of the defensive line in free agency, but they could be losing quality players in the pool.
With Julius Peppers signing a three-year deal with the Green Bay Packers on Saturday morning, it meant that's one less name to evaluate on the free-agent list.
So now the Cowboys hope that Dallas native Henry Melton doesn't sign with anybody else before his scheduled visit to Valley Ranch this weekend. He might not even get here until Monday.
Jared Allen, Anthony Spencer and Robert Ayers are other names the Cowboys have an interest in.
Yet because of the Cowboys' limited monies in the salary cap, they are going to be careful with any signing. They want a quality player but at their own price.
None of the free agents the Cowboys sign are going to get that five-year, $50.1 million deal that Brandon Carr got two years ago when he signed on from Kansas City.
Expect a low base salary for a free agent with a nice $6 million to $8 million signing bonus for a two- or three-year deal.
Spencer (microfracture) and Melton (ACL) are coming off injuries, so teams, while interested, could have some leverage from a financial basis due to the health of the players.
The Cowboys have time to make a move, but finding the player they want in free agency is growing tougher.


text: Housing Interventions and Control of Asthma-Related Indoor Biologic Agents: A Review of the EvidenceKrieger, James MD, MPH; Jacobs, David E. PhD, CIH; Ashley, Peter J. DrPH; Baeder, Andrea MPH; Chew, Ginger L. ScD; Dearborn, Dorr MD, PhD; Hynes, H. Patricia MA, MS; Miller, J. David PhD; Morley, Rebecca MSPP; Rabito, Felicia PhD; Zeldin, Darryl C. MD Erratum In this online-only supplement to the September/October 2010 issue, a correction must be noted for the article by James Krieger et al. In the section "House Dust Mites," the unit of measure in the following sentences was published as μg/mg. That is incorrect. The unit of measure should be given as μg/g, as shown in the text below. "A body of clinical and epidemiologic evidence suggests that exposure to Der p or Der f antigens at levels greater than 2 μg/g is associated with sensitization and above 10 μg/g with exacerbation of established asthma in mite-sensitized persons.9,10 These cut-points are often used to assess exposure risk in field studies. A recent survey found that more than 80% of homes in the United States have detectable levels of house dust mite allergen in the bedroom, 46% have levels above 2 μg/g, and 24% have levels above 10 μg/g.11" Journal of Public Health Management and Practice. 16(5):, September/October 2010. Journal of Public Health Management & Practice: September/October 2010 - Volume 16 - Issue 5 - p S11–S20 doi: 10.1097/PHH.0b013e3181ddcbd9 Review of Housing Interventions Abstract In Brief Author Information Subject matter experts systematically reviewed evidence on the effectiveness of housing interventions that affect health outcomes, primarily asthma, associated with exposure to moisture, mold, and allergens. Three of the 11 interventions reviewed had sufficient evidence for implementation: multifaceted, in-home, tailored interventions for reducing asthma morbidity; integrated pest management to reduce cockroach allergen; and combined elimination of moisture intrusion and leaks and removal of moldy items to reduce mold and respiratory symptoms. Four interventions needed more field evaluation, 1 needed formative research, and 3 either had no evidence of effectiveness or were ineffective. The 3 interventions with sufficient evidence all applied multiple, integrated strategies. This evidence review shows that selected interventions that improve housing conditions will reduce morbidity from asthma and respiratory allergies. This review discusses housing interventions and control of asthma-related indoor biologic agents and shows that selected interventions that improve housing conditions reduce morbidity from asthma and respiratory allergies. Chronic Disease and Injury Prevention Section, Public Health—Seattle and King County, Seattle, Washington (Dr Krieger); National Center for Healthy Housing, Columbia, Maryland (Dr Jacobs and Ms Morley); Office of Healthy Homes and Lead Hazard Control, US Department of Housing and Urban Development, Washington, District of Columbia (Dr Ashley); Centers for Disease Control and Prevention, Atlanta, Georgia (Ms Baeder and Dr Chew); Department of Environmental Health Sciences, Case Western Reserve University, Cleveland, Ohio (Dr Dearborn); Boston University, School of Public Health, Boston, Massachusetts (Ms Hynes); Carleton University, Ottawa, Ontario, Canada (Dr Miller); Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, Louisiana (Dr Rabito); and National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina (Dr Zeldin). James Krieger (Chair), David E. Jacobs, Ginger L. Chew, Dorr G. Dearborn, H. Patricia Hynes, J. David Miller, Darryl C. Zeldin, and Felicia Rabito were members of the expert panel reviewing the evidence for housing interventions to control asthma-related indoor biologic agents. Correspondence: James Krieger, MD, MPH, Public Health—Seattle and King County, Chinook Bldg, Ste 900, 401 5th Ave, Seattle, WA 98104 (email@example.com). Disclaimer: The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention. This work was supported by a cooperative grant with the Centers for Disease Control and Prevention, Office of Healthy Homes and Lead Poisoning Prevention, and the National Center for Healthy Housing. In addition, funding was provided by NIH P30 ES 009089. © 2010 Lippincott Williams & Wilkins, Inc.


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Read More
- Small-Group Halong Bay Day Cruise
- Small-Group Saigon Night Tour & Dinner Cruise
- Local Flavors Food Walking Tour
- Small-Group Full-Day Mekong Delta Cruise
- Small-Group Half-Day Tour of Cu Chi Tunnels
- Half-Day Cu Chi Tunnels Tour
- Mekong Delta, My Tho & Ben Tre Tour
- Halong Bay Full-Day Boat Cruise
- Cu Chi Tunnels Excursion
- Small-Group Half-Day Ho Chi Minh City Tour
The Starcity Saigon Hotel is a sumptuous four star property located only a five minute drive away from the Tan Son Nhat International Airport. Guests staying here will find themselves strategically located for a quick transfer to and from the airport, as well into the heart of the city, to visit such attractions as the Sai Gon Opera House, the Reunification Palace, the War Remnants Museum, the many handicrafts, fruits and souvenirs of the Ben Thanh Market, religious destinations such as the Thien Hau Pagoda and Central Mosque. The rooms at...
Rooms available starting at USD 80 - Book Now!
Rooms available starting at USD 80 - Book Now!
Thanh Binh Hotel 2, situated in Ho Chi Minh City dynamic Tan Binh district, offers guests a taste of sleek, urban living in the heart of one of Asia most fascinating cities. The hotel is conveniently close to many excellent restaurants and shops, and is only 3km from Tan Son Nhat International Airport, making it a good option for those travelling for both business and pleasure. The Palace of Independence is only fifteen minutes drive from the hotel, and there are many other attractions close by, including vibrant Cholon Market and the War...
Rooms available starting at USD 23 - Book Now!
Rooms available starting at USD 23 - Book Now!
Saigon Sunny Hotel is located on the quiet place of District 1, near city center, it takes only 10 minutes to drive to Tan Son Nhat International airport and Saigon railway station. Saigon Sunny Hotel offers a convenient 24-hour reception as well as a safe, a business centre and a concierge. For a fast and effortless arrival and departure experience, guests can benefit from the Saigon Sunny Hotel's express check-in kiosk. Travel arrangements can be made at the hotel's tour desk. All 27 rooms at Saigon Sunny Hotel are included a private...
Rooms available starting at USD 23 - Book Now!
Rooms available starting at USD 23 - Book Now!
Hotel 199 is one of Ho Chi Minh City freshest new arrivals, and was only opened in 2011. As a result, the modern, stylish ambiance is as you would expect from a new hotel, combined with all the luxury and comfort of a three star hotel. The hotel is only fifteen minute drive from Tan Son Nhat International Airport, making it a highly convenient option for both the business traveller and the holiday maker, and it is also close to many of the city principal attractions, including the Palace of Independence. Sights such as the thought-provoking Cu...
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Measuring consumer knowledge of life insurance products in South Africa
Ramchander, Manduth
MetadataShow full item record
The financial services industry is characterized by product suppliers having more information than consumers regarding product features and services. The purpose of this article is to explore this information asymmetry with particular reference to the life insurance industry. Financial advisors, acting as intermediaries, are charged with the task of resolving this asymmetry through mandatory disclosures demanded by regulation. In South Africa, the Financial Services Board (FSB) monitors, regulates and supervises the financial services industry through the Financial Advisory and Intermediary Services Act of 2002 and The Code of Conduct for Financial Advisors. This paper distinguishes financial products from other products and highlights the need for disclosures regarding product features, by financial advisors. Using multistage sampling a national survey was conducted to establish whether consumers are knowledgeable of the features of basic insurance products. The findings were that consumers have a low to very low level of understanding of the features of basic insurance products. The study makes an important contribution to insurers' understanding of consumers' knowledge regarding the features of basic life insurance products. Furthermore, the findings would also contribute to insurers understanding the level to which intermediaries resolve the information asymmetry between product suppliers and consumers.
Ramchander, M. 2016. Measuring consumer knowledge of life insurance products in South Africa . South African Journal of Business Management. 47(2): 67-74.


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Flip through the Summer Camp and Events book to see what we offer.
Explore Our Camps
The crackle of the campfire, the splash of canoe paddles in the lake, the whoosh of an arrow flying towards the bullseye—these are the sounds of a beloved summer tradition: Girl Scout camp. It's a special time that allows your girl to unplug from her electronics and connect to nature, peers, and herself. She will build skills and confidence through new experiences under the guidance of caring, trained adults. Oh—and she'll have a ton of fun too!
First time at camp?
Welcome to your girl's new "happy place." Whether she wants to have fun in the sun at Day Camp, tell stories around the campfire at Resident Camp, or try a short-term Outdoor Experience like an afternoon or weekend at camp, we have a great fit for every girl.
How to begin:
If you aren't currently a Girl Scout, you can register as a girl or adult member using COMAR. Then sign up for your camp sessions.
Once you sign up for your session, you will receive additional information such as directions, a packing list, and all the necessary paperwork.
Bringing the Troop?
Come to Camp join other troops for a special Troop Overnight Event, or plan your own outdoor adventure with Troop or Service Unit Camping. There are lots of fun ways to get your girls in the great outdoors!
Want to work at camp?
Change lives, gain skills, and have a summer you will never forget! Check out Summer Job Opportunities to learn more and apply online.


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Template >> Website - Dashboard User Interface Template 1456 by Florin Constantin @ CreativeMarket
File Size: 4.18 MB; Requirements: Adobe CS4+; Layered: Yes; DPI: 326 DPI; Dimensions: 1160 x 2000 px.
The pack contains: Buttons, On/off switch, List items, Sliders, Knobs, Hostin configorator, Dropdown, Tooltip, Line charts, Pie chart, Calendar.
It's all editable in PSD with vector shapes.
Layers are grouped and named. Pixel perfect.
If you'll have trouble or question just leave your comment here or email me.
Keywords: dashboard, template, user interface, clean, pixel perfect.


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HTC tipped to make Google's 2016 Nexus phones
HTC has reportedly been contracted to manufacture both of Google's Nexus handsets this year, which will be similar in size to the 5X and 6P.
Last year, Google asked LG and Huawei to make the Nexus 5X and 6P respectively. It looks like HTC alone will be trusted with making the two Nexus handsets this year.
Rumours circulating on Chinese social network Weibo indicate that one handset will clock in at 5-inches, while the other will be a 5.5-inch phablet. Little else is known about either handset just yet.
HTC made the first Nexus phone in 2010 and the Nexus 9 tablet in 2014, so it has a proven track record.
The HTC-built Nexus phones are expected to launch this autumn.
Online Editors


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Support the Community
The Everyday Prayer
Icon of the Holy Face
Memory of the patriarch Abraham. In faith he journeyed to a land that he did not know, but that was promised to him by God. Because of this faith, he is called the father of believers by Jews, Christians and Muslims.
Reading of the Word of God
Alleluia, alleluia, alleluia
You are a chosen race,
Alleluia, alleluia, alleluia
Genesis 22,1-18
It happened some time later that God put Abraham to the test. 'Abraham, Abraham!' he called. 'Here I am,' he replied.
Alleluia, alleluia, alleluia
You will be holy,
Alleluia, alleluia, alleluia
Abraham is the father of our faith. In scripture, he stands as the figure of one who listens first to the voice of God, a voice that called him to leave his land and to go toward a place and a life he did know, but that the Lord had prepared for him. Abraham obeyed the voice and departed, leaving behind his father's house. During his life he faced difficult moments and trials, such as the sacrifice of his only son, Isaac. God had promised Abraham an heir, and yet Abraham obeyed the Lord's command: "Take your son, your only son Isaac, whom you love, and go to the land of Moriah, and offer him there as a burnt offering on one of the mountains that I shall show you." Human reason could not explain God's command, but Abraham obeyed God rather than human logic and headed up the mountain Moriah with his son. Seeing Abraham's radical faith, the Lord did not take his only son. Rather, God returned that son to him in faith and he became the first born of a multitude. For his faith, the Lord called and regarded Abraham as a "friend", so much so that the Lord was not able to hide from him his intention to destroy Sodom. And Abraham, as a friend of God, was able to intercede on the city's behalf. Patriarch of all believers, Abraham comes to meet us at the beginning of this new millennium so that we, along with him, will readily obey God's call with all of our heart.
Memory of the Saints and the Prophets


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By Treasure
Chapter 4
"This meal is superb, sempai!" With eyes closed while savouring the dish, Nodame complimented Shinichi.
"Baka!" He answered back, but with a broad grin on his lips.
"I really did miss your cooking, sempai."She's all giddy and excited.
"Then why aren't you coming over dinner?" Shinichi closed in at her.
"Ano . . . ." In her mind, the interrogation is now starting; she better dodge them or else, she'll be toasted. "Nodame became busy with school and work." Dodging questions with truths, yes this will be her strategy.
"But you could call?"
"Ano . . ." With no more reasons to think, she changed the topic, "ah, sempai, is it okay for me to learn modern music? I've heard this song on the radio and I kind of like it, I remember the title as The Prayer."
"I don't think I know that song. Could you play it?" Shinichi started picking up the used dishes.
"Okay, after I've done the dishes." Nodame picked up the remaining used utensils and brought it to the sink.
Shinichi could have told her to play the piano right away but he thought that this was the first time Nodame volunteered to do the dishes, so he let her be. "Oi Nodame, don't break anything. You can start playing after you're done with the dishes, I'll just take a shower."
"Hai, sempai!" Something excites her with the word "shower" but she definitely holding the excitement, she doesn't want to be pushed away again.
'Nodame is maturing. Maybe that job at the cafe is doing wonders in some of her disposition.' Shinichi said to himself as he went in the bathroom. There's a small satisfaction in his thoughts. But he's hoping that her hentai ways did not totally left her.
A soft melody started to play in the piano while Shinichi was halfway through his bath. "Ah, it sounds good, she really has good ears when it comes to music; but she must not indulge in modern music, not just yet. She must know and learn with the masters first."
The music had stopped when he stepped out of the tub. 'I must have dozed off. Maybe Nodame is already asleep by the piano or the sofa, I need to hurry and give her a blanket before she gets cold.'
But Nodame was nowhere to be found in his apartment. All she left was a colourful note.
Dear Sempai,
Thank you very much for the dinner. I enjoyed it very much and looking for the next menu you would cook for me. Nodame needs to go home as she has classes very early in the morning. Will sempai visit Nodame again at the cafe?
'Darn! Why did she have to go? I was even thinking of letting her have the bed for tonight. =( Maybe she thought I would let her sleep on the sofa. Maybe the sofa is too much for her.' He was scratching his head. 'Maybe I should tell her ahead of time that she could sleepover too anytime she wants.'
He briefly stopped and then spoke to himself again. 'Why am I so paranoid these days, and why do I miss her so much? Should I tell her? No, maybe not, she'll plague me with sweet nothings if I do that. And . . . . and she would surely bring her things here again . . . . those dreadful 'Puri Gorota figurines.'
Two days later, Chiaki decided to visit Nodame at the cafe again. He even bought a small bunch of carnations. Sorry he doesn't know her favourite flower, sure he'll know later. Nodame is not the one to pass to comment on these matters and when she does, he'll need to remember that. But then again, he decided to leave it in his apartment; he wanted to preserve that look on her face, that expression when she received those flowers. He wanted that expression to be his and his alone.
'What must I cook tonight?' He was taking a mental inventory of what's in his fridge as he was walking towards the cafe. 'Well, I did buy some pizza dough, several kinds of pasta and a nice chunk of salmon. If she wants some ebi tempura, we could have it for lunch. That's right! I'll ask Nodame to come and take a walk with me tomorrow morning; we could pass by the fish monger and buy some more sea foods for lunch. I know she hasn't any class on weekends.'
Chiaki was really inspired at that time. Planning on how to entice Nodame to stay with him that weekend without revealing much of his emotion (he's convinced that his style is like emotional aikido – use your opponents strength to your advantage). He was even humming Beethoven.
He seated himself almost to the farthest corner of the cafe. He could observe Nodame a bit longer before he needs to place an order. Lately, he really finds Nodame prettier than before or maybe she just smelled sweeter.
Then something caught his attention that made his blood seethe. The dirty old man from before was seating a few tables from him. He was with another man, another senior citizen, and they were speaking in Deutsch, both agreed to make a pass at Nodame, and if she won't agree to their offer, a tap on her rump would make them happy.
'Trying to make a pass, with my girl? This is totally preposterous! As if Nodame would agree to that!' Chiaki could no longer contain his anger, he went to the old me's table and spoke to them, also in Deutsch and in a loud voice "You would do nothing of such. Both of you shall leave immediately or, I'll call on the police and report your conspired harassment attempt on with one of the waitresses here."
Both men were shocked to know that somebody overheard them. They don't want to be questioned by the police, not at their age, so they decided to heed Chiaki and left the place in mere seconds.
"I guess you should find another job, one that does not expose you to so much harassment." Chiaki suggested to Nodame as they were walking towards his apartment.
"Thank you for looking out for Nodame, senpai. Ahee." Nodame clutch her bag tightly, acting demurely. Chiaki all the while waiting for her to embrace him, but it didn't happen.
Annoyed, Chiaki embraced Nodame. The surprise didn't register to her until after a few seconds. Chiaki tightened his arms around her as if trying to be one with her.
"Senpai, Nodame likes to be hugged by you, but not this tight." Chiaki let her go and started to walk again as if nothing happened. "We better hurry up, it's getting late for dinner." He held her hand and started walking briskly.


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Indiana Basic Business Taxes 2012
Economic development, finance, and tax organizations provide a range of incentive programs to initiate new business and commercial investment. Specific programs include Economic Development for a Growing Economy (EDGE) Tax Credits, Headquarters Relocation Tax Credits, and Hoosier Business Investment Tax Credits (HBI).
21st Century Research and Technology Fund:
Indiana's 21st Century Research and Technology Fund (21 Fund) focuses on entrepreneurial ventures that have demonstrated a market potential for commercialization of innovative technologies. The 21 Fund provides financial support to highly innovative Indiana-based companies, thereby helping these firms make the transitional leap from general research and development to product development while also creating high-wage, high-skill, high-tech Indiana jobs and diversifying the state's economy. The 21 Fund encourages an environment of innovation and cooperation among Indiana universities and businesses to promote research activity through collaborative partnerships.
Industrial Development Grant Fund:
The Industrial Development Grant Fund provides financial support for infrastructure improvements in conjunction with projects creating jobs and generating capital investment in Indiana. This grant provides money to local governments for off-site infrastructure projects associated with an expansion of an existing Indiana company or the location of a new facility in Indiana.
Patent Income Exemption:
Taxpayers are exempt from certain income derived from qualified utility and plant patents. Qualified taxpayers are eligible for an exemption of 50 percent of patent income for each of the first five years. The exemption percentage decreases during the next five years to 10 percent in the 10th year. The total amount of exemptions claimed by a taxpayer may not exceed $5 million per year. This benefit is available only to companies with 500 or fewer employees.
Skills Enhancement Fund (SEF):
The Skills Enhancement Fund (SEF) provides financial assistance to businesses committed to training its existing or expanding workforce. Trainees must be permanent, full-time, Indiana residents. SEF reimburses eligible training expenses during a two-year term. IEDC does not provide reimbursement for training for: (1) new employee orientation, (2) compensation of trainee wages during the training, and (3) OSHA or other legally required safety training. Companies can receive reimbursement of up to 50% of eligible training expenses. Businesses receiving SEF training assistance must commit to continuing their operations and maintain certain employment levels at the location where the SEF training assistance is provided for at least five years after the 2-year training grant term is completed.
Shovel Ready Program:
Indiana's Shovel Ready program improves the ability of Indiana communities to attract new economic development and jobs while reducing the site selection and facility construction time for business. The Shovel Ready program lowers the cost of site development and improves efficiency of the state and local permitting process by certifying sites as "ready for development." The program strives to reduce up to 30 percent of the total permit time at the state level for businesses that choose to move into a Shovel Ready site.
Regulatory Ombudsman:
The Indiana Economic Development Corporation's regulatory ombudsman assists in the process of obtaining the permits and approvals necessary for a business operation. The ombudsman serves as a liaison between companies, communities, local economic development organizations and regulatory agencies.
Indiana State Contact:
Indiana Economic Development Corporation
One North Capitol, Suite 700
Indianapolis, IN 46204
Toll-free: 800.463.8081
Tel: 317.232.8800
Fax: 317.232.4146
Incentive and tax information is provided to Area Development by each state's economic development or commerce agency for information purposes only and is subject to revision at any time by the state government. Please contact the state agency directly for full requirements and offerings.
2017 Top States for Doing Business: Georgia Ranks #1 Fourth Year in a Row
Mark Crawford, Area Development
Leading Locations for 2017: West Coast "Tech" Cities Top List, Smaller MSA's Show Workforce Chops
Area Development Research Desk
Mark Crawford, Area Development
2017 Gold & Silver Shovel Awards Recognize States Compiling Healthy Rosters of New and Expanded Facilities
Geraldine Gambale, Area Development Magazine
Steve Stackhouse-Kaelble, Area Development
31st Annual Survey of Corporate Executives: Confidence in U.S. Economy, Need for Investment in Infrastructure Reflected
Geraldine Gambale, Area Development Magazine
13th Annual Consultants Survey: Confidence in U.S. Economy, Concern Over Proposed Trump Policies
Geraldine Gambale, Area Development Magazine
Automation Takes Hold, But Humans Still Needed
Geraldine Gambale, Area Development Magazine
Industrial Manufacturers' Optimism Reflected in Expectations of Higher Revenue Growth, Increased Capital Spending
Geraldine Gambale, Area Development Magazine
In Focus: Has the Moment for Infrastructure Revival Arrived?
Walter Kemmsies, Ph.D., JLL
Where Should Aerospace Companies Invest? Evaluating Aerospace Manufacturing Hubs
Scott Thompson, PwC
2016 Top States for Doing Business: Georgia Back in Top Spot AgainAll Studies/Research/Papers


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We and our strategic partners are looking for outstanding, ambitious, and humble individuals who want to join our growing team. If you believe in rolling your sleeves up, jumping on opportunities, and doing whatever it takes to succeed, then we will be the right platform to turbo charge your career. If, on the other hand, you are seeking to be told what to do, want the well-trodden path of 100s of people before you, and are uncomfortable with ambiguity or a fast moving environment, then we will not be an appropriate match.
We look forward to getting to know you and hope to welcome you to our growing team. Below a list of our current openings.