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"Lorenzo was braking ten, twelve metres after me and Dovi. It was quite impressive, because we were already on the limit"
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Jorge Lorenzo the latest on the brakes? It's not a statement you'd normally associate with the triple MotoGP champion, whose silky smooth riding-style relied on corner speed rather than braking while at Yamaha.
But Pramac's Danilo Petrucci has revealed that at Jerez, where Lorenzo took his first Ducati podium, the Spaniard was braking later than any other rider on the Desmosedici GP17.
"Lorenzo made the difference in Jerez, because looking at his data, especially on braking, he was very very fast," Petrucci said at Le Mans on Thursday. "Especially because usually, the Ducati riders who brake deepest are me and Dovi.
"It was quite strange, because he could brake later and with more pressure. I never had the chance to see the data of Lorenzo with Yamaha, but with Ducati, usually he brakes a little bit earlier and with less pressure.
"In Jerez, especially at Turn 6, at the end of the back straight, and Turn 13, the last corner, Lorenzo always brake ten-twelve metres after me and Dovi. It was quite impressive, because we were already on the limit."
Might it have been because Lorenzo opted for a medium, rather than the hard, front tyre?
"I don't think it's only the front tyre. Sincerely, when we tried the two tyres, the difference was not big, but we were scared about the consumption of the front, so we decided to use the hard, like a lot of riders. I don't know... I think Lorenzo started to ride the bike in the proper way, and this will be a problem for me! [Laughs]"
Lorenzo, who didn't use the rear brake at Yamaha, has been learning how to get the most from the technique at Ducati.
"Like me and Dovizioso, he is using the thumb brake," Petrucci confirmed, "because without the rear brake, it's quite impossible to use the Ducati. We have two rear brakes, one for the foot and one for the thumb, and it's very important.
"We use it a lot inside the corner, to try to stop the bike without weight transfer.
"For example, if you are going into a tight right-hand corner and you try to brake on the front, for sure the weight goes on the front and when you are approaching the exit of the corner, if you pull down the front of the bike, the bike turns less.
"So if you use the rear brake, the front comes up and helps you to turn the bike better, to let the bike turn back. Especially we use it when we are releasing the front brake and opening the throttle. In that point, the using of the rear brake is continuous. So it's like the rear brake gives the bike more stability, and this is better."
Petrucci, who matched his best finish of the season with seventh at Jerez, is looking for a strong Le Mans to springboard into his home round at Mugello.
"I want to be fast like the two races, like in Jerez or in Austin, because I want to arrive in Mugello in a positive way, and I want to show, especially to myself, that I can stay in the front every race," he said.
"I understood that I can be in the middle of the factory guys, so my target is to be for sure one of the best Ducatis at the end of the race. It's very difficult, in Jerez I finished two seconds behind Dovizioso, like in Austin, but my qualifying practice was not so good."


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Sometimes in life we need encouragement and other women to lean on. Women with a Voice, hosted by Sue Frost and the Inspire Connecting Communities ladies, invites you to discuss topics all women can relate to in a safe and friendly environment. Join in at Coast Restaurant, 160 Maroochydore Road, Maroochydore and enjoy delicious cuisine provided by The Canapé Project. Tickets are $60 and include a three course meal and a glass of wine. For more information, email email@example.com. Bookings are essential.
Women with a Voice
What's On
Coast Restaurant, 160 Maroochydore Road, Maroochydore 4558Visit Website

subset: commoncrawl


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Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.
Time of drug administration, genetic polymorphism and analytical method influence tacrolimus pharmacokinetics:a population pharmacokinetic approachFlora Tshinanu Musuamba, Michel Mourad, Vincent Haufroid, Roger K. Verbeeck and Pierre Wallemacq1Department of Clinical Biochemistry, 2Department of Pharmacokinetics, metabolism , and toxicology, Université Catholique de Louvain, Brussels; Belgium
Tacrolimus (TAC) is an immunosuppressive agent produced by Streptomyces tsukubaensis and used in combination with mycophenolic acid or corticosteroids for the prevention of acute rejection after solid organ transplantation.[1] The pharmacokinetics (PK) of TAC are characterized by a considerable inter- and intra-patient variability. In addition, TAC has a rather narrow therapeutic window. As a consequence, dose individualization and TAC therapeutic drug monitoring to determine the actual exposure may improve the efficacy and tolerability of TAC and is currently recommended. It has been demonstrated in rodents that TAC PK, activity and toxicity are influenced by the time of drug administration. One of the causes of discrepancies between results published for TAC can be found in the differences in the analytical methods used to quantify TAC in the patients' blood specimens. These methods include specific and non specific immunoassays and chromatographic methods.
Patients and samples: Nineteen adult renal allograft candidates in one Belgian university hospital (Cliniques universitaires Saint Luc) were included in this study. All patients received two doses of TAC (0.1 mg/Kg body weight) orally at 8.00 am and 8.00 pm.
Full PK profiles for TAC during two dosing intervals were determined after the morning and the evening doses. For the determination of the full pharmacokinetic profiles, 2 mL blood samples were collected in EDTA tubes and kept frozen at -20 °C until analyzed. Sampling times were as follows: before (0) and at 1, 2, 4, 8 and 12 hours following TAC administration. The patients were not under corticoids, and were not followed for hepatic insufficiency
Assays comparison: Tacrolimus concentrations measured both by MEIA and LC-MS/MS analysis from adult kidney transplant candidates were used to evaluate the performance of IMx in the clinical setting, using LC-MS/MS as a reference. Tacrolimus LC-MS/MS concentrations were plotted against their corresponding MEIA values, and against the difference between the two methods, as described by Bland and Altman.[13]
Population pharmacokinetics analysis:Nonlinear mixed effects modelling was performed by using NONMEM Version VI. FOCEI was used throughout the entire modelling process. TAC IMx and LC-MS/MS blood concentrations were modelled and different structural models were tested: one-, two- and three-compartment models with first-order or zero-order absorption and with or without a lag time.
The aims of the present study were: (1) to identify and model the effect of demographic, clinical and genetic factors and time of drug administration on TAC pharmacokinetic variability, by using nonlinear, mixed-effect modelling techniques; (2) to assess the influence of the analytical method by modelling separately the blood TAC concentrations measured in the same patients, by Microparticle Enzyme ImmunoAssays (MEIA) and by LC-MS/MS.
Figures 2 and 3. Bland and Altman method comparison plot of TAC concentrations obtained by LC-MS/MS and IMx.
The retained final model validation by bootstrapping and case deletion diagnostics gave satisfactory results. The distribution (5th and 95th percentiles) of the 1000 simulated concentration-time curves are shown in Figure 4.
A good agreement was found between the results obtained by both methods, even though IMx values were generally slightly higher than LC-MS/MS values, as expected. (see Figure 1)
Figure 1. Bland and Altman method comparison plot of TAC concentrations obtained by LC-MS and IMx.
Figure 4. Visual predictive check (VPC) results on 1000 simulations
The inter-individual variability was modelled by an exponential model, and a mix model was retained to describe the residual error. Nevertheless, supplementary additive and proportional error terms were needed in case of IMx concentrations. The following covariates showed significant influence on PK parameters during the covariates inclusion process: time of drug administration on absorption (K12), and CYP3A5*3 and ABCB1 genotypes on the CL/F. Figures 2-3 show diagnostic plots of the performance of the final model.
A two-compartment model with first-order absorption and elimination, best fitted the TAC blood concentrations, irrespective of the assay methodology.
The final model was found to be stable and generated parameters with good precision. This is the first POP-PK study confirming the chronopharmacokinetics of TAC and showing an effect of ABCB1 genotype and analytical method on TAC PK parameters. These results may be a helpful for TAC dose individualisation.
Address for contact: FT Musuamba - Department of Clinical Biochemistry, Department of Pharmacokinetics, Metabolism, and Toxicology
Av Hippocrate 10, B-1200 Brussels, Belgium – [email protected]


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All prices are in All prices are in USD
Purse Money Increased to $5,000 Each Night - Full Size Stock Car Added
Loud destruction is what you are in store for at the Great Geauga County Fair Demolition Derby shows. Full size compact stock heats
Purse money increased! Rules and Registration - click here >
For more information, email firstname.lastname@example.com or call 937-241-3556
Presented by Cavalcade Thrills - Thursday Night and Saturday Night
Posted by Unknown on 4th Sep 2015
We love the derby, we've been going on thursday nights for years! Thanks for putting on a great show.
Posted by Unknown on 1st Sep 2015
we love the demo derby- always exciting! we ordered our tickets early this year because they sell out so quickly! great fun for the family, but can get loud at times.


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This resturant is within walking distance to us and we are there almost weekly for dinner - we love sitting outside - try the BBQ sandwich or breaded tenderloin. And in the winter...
Moe and Johnny's lacks character simply because it's owner does. The bulldog will never be on 62nd street. That's original.
The Scene
Formerly the Bulldog, this bar, restaurant and music venue packs in a mostly twentysomething crowd every night of the week. A family-style restaurant serving burgers, pizza and salads by day, this roomy watering hole transforms into a packed social hub by night. It's no surprise with Butler University so close.
The Booze
Daily beer and drink specials give more bang for your buck on everything from Absolute Vodka cocktails to margaritas. There are seven beers on tap including Guinness, Bass and Coors.
While You're There
Local bands play every Friday and Saturday night. Though the club hasn't honed in on one type of music, most of the bands have a rock edge to them. Pool tables, video games, four big-screen TVs and a team of flirty waitresses always make for an interesting evening.
From family friendly trips with kid friendly activities to local plumbers lawyers, spas, and contractors. Judy's Book has millions of listings and reviews for the best and not so great. Whether you're looking for a specific business or just trying to discover great places we make it easy. We're a family oriented site focusing on bringing trusted reviews and recommendations to moms and others. Green and Sustainable places are becoming more relevant to Judy's Book users, have a favorite place? Write a review and tell users why it's Green!


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Parents of children with special needs face unique emotional and practical challenges that are seldom addressed by the medical community. In Special Kids Need Special Parents, Judith Loseff Lavin-herself the parent of a child with special needs-draws on interviews with health care professionals, nationally recognized authorities, and other parents to give readers the answers, advice, and comfort they crave.
* Coping with chronic pain, sleep problems, and frequent hospitalizations
* Dealing with feelings of grief and anger
* Choosing a therapist
* Finding suitable, reliable childcare
* How to cope with teasing
* The impact a child with special needs can have on a marriage, siblings, and grandparents
* Finding cosmetic, prosthetic, and orthotic help
* and more
An unflinching look at the multiple challenges of raising a child with special needs...a wealth of useful information. (Adele Faber, co-author of How to Talk So Kids Will Listen and Listen So Kids Will Talk)
A wise and helpful book written by someone who knows what needs to be said and has earned the right to say it. (Rabbi Harold S. Kushner, author of When Bad Things Happen to Good People)
Author Bio: Judith Loseff Lavin has written for the Chicago Sun-Times and many magazines. A graduate of Northwestern University with a degree in secondary teaching, Ms. Lavin is involved with several organizations that promote the welfare and progress of children with special needs.


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Cat and Dog People Have Certain Distinct Traits
While you already probably know if you'd rather have a dog or cat as a pet,
you may not be aware that cat people and dog people have distinct personality
Research findings suggest that dog and cat owners have certain
characteristics that make them more attuned to owning a canine or a cat.
Dog People Generally Exude More Confidence
For example, studies show that people who own dogs are generally more
confident and aggressive in nature. Cat people, on the other hand, tend to be
more introverted and socialize less. So, if you're hosting a cookout, you'll no
doubt see more dog people show up for the party than people on your list who
happen to own a cat.
Dogs at Social Event - Sometimes Called Puppy Parties
Many Cat Lovers Like to Express Themselves Artistically
Of course, that doesn't mean that cat people shy away from all gatherings. If
you're having an art exhibit, for example, then feel free to invite your cat
loving friends as cat people generally like attending artistic or creative
While dog owners typically are more traditional, cat lovers tend to
think outside the box more frequently.
Dog People are Generally Better at Planning
Studies also reveal that cat people are not planners like dog people but
enjoy spontaneity more. Nevertheless, people who favor felines are cooperative
souls and generally adapt better to situations where people have to work as a
group or team. In some cases, dog people, although cooperative too, tend to be
less compliant.
Cat People Prefer Cats over Dogs 100%
All in all, owners of dogs, just like their canines, tend to be extroverts
while owners of cats are usually more reserved. Researchers have also found that
cat owners who are defiantly cat people, when they were polled, that they'd
never consider adopting a dog. However, those people who've always had a dog as
a pet said they wouldn't rule out the possibility of owning a cat.
Are you a cat person or a dog person? And why do you think that is?
Please comment below!
Top Lists:
18 Richest Animals in the World
15 Exotic Pets You Could Own Today
Top 20 Common Substances That Are Toxic to Cats and Dogs
Animal Actors: Pets in the Film, TV, and Print Industry
Caring for a Yorkshire Terrier: Facts You Should Know
Caring for a Pig as a Pet: The Pot-bellied Pig and the Micro Pig
Difference Between a Cat Person And a Dog Person
Should You Microchip your Cat or Dog?
How to Raise and Care for Pygmy Goats
Caring for Unique Pets: The Leopard Gecko
Use Food-Grade Diatomaceous Earth to Kill Fleas Naturally
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Top 15 Dog Breeds For Home Protection
15 Fascinating Facts About The Mastiff
How To Teach Your Dog to Hunt for Truffles
Caring for an English Bulldog: Tips and Basic Info
Cranial Cruciate Ligament (CCL) Tears in Dogs: Treating the Injury
How To Keep Your Dog free of Heartworm Disease
Dog With Separation Anxiety?
Top Lists:
Top 6 Qualities in an Awesome Cat
How to Control Fighting Felines
How to Get Your Cat to Exercise
Fish 101 for the Hobbyist: The Fish's Body and Senses
Buying a Saltwater Aquarium: What You Need to Know
Graduating to a Saltwater Tank
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inbriefMarch 2010
A four-year mandate to provide ethical research for the €280billion ($382bn, £244bn) Norwegian oil fund has been awarded to Sweden-based GES Investment Services.
For full access to EP Journal, become an Ethical Performance member. To join, click here.
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Faking her own death to escape her murderous husband, Rainie Hall takes refuge in the rural community of Crystal Falls, where she finds work as a bookkeeper on a horse ranch run by dangerously good-looking Parker Harrigan. But as their initial attraction blossoms, Rainie fears she can never escape retribution from the man who has sworn to kill herand that her mere presence could jeopardize everything the Harrigan family holds dear.
With her powerful, abusive husband planning her murder, Rainie Hall Danning has no choice but to run. "Disappearing" from a cruise ship, she becomes Anna Pritchard, flees Seattle, and finds work at Parker Harrigan's horse ranch in rural Oregon. Parker soon senses that something is wrong with his wary, man-shy bookkeeper. As he learns the truth, he makes it a priority to help the woman he has come to love regain the power and self-confidence that had been stripped away. But clever, psychotic Peter Danning is hot on his wife's trail-and while Rainie may be safe for now, she won't be for long. A damaged but ultimately resilient heroine, a strong, intuitively caring hero, and an intensely loyal, rowdy family who protect their own quickly draw readers into this tense, well-crafted, riveting tale that keeps the suspense on target. Anderson's novels often address serious issues, including women escaping abusive situations. A powerfully compelling story of survival, healing, and hope, this is the third in the Harrigan family stories and one of the author's best to date. Anderson (Morning Light), who lives in rural Oregon, is noted for her sensitive, insightful, family-centered romances.


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Contact Info / Websites
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Extreme Happiness
Rated 5 / 5 stars
This is awesome.
I would like to see more of this character haha. Incredible.
Brewster responds:
Thanks! I can definitely see this guy coming back some day.
Halo Reach: Armor Locked
Rated 5 / 5 stars
Very good.
Your art work is beautiful and I think the concept is great. Keep up the good work. ;)
DoomzDayChikn responds:
appreciate it very much, and will do
Sugar Shenanigans
Rated 2.5 / 5 stars
Good Enough
i enjoyed the simplicity of it. Some parts were funny as well. If you would get a better voice actor for the short guy i would have given seven stars.


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wikiHow to Act Like an Adult
Two Parts:Adjusting Your LifestyleAdjusting Your Attitude and DemeanorCommunity Q&A
Are you 18 and older, but feel like a child? Do you have a hard time acting like an adult towards others, even though legally you are one? Being an adult can be a difficult thing to do, especially if you aren't sure what being an adult is all about. Making adjustments to your lifestyle and your general attitude towards others can bring you one step closer to acting like an adult.
Part 1
Adjusting Your Lifestyle
1Dress like an adult. Act the part by investing in clothing that makes you feel like a grown up. Trade in your band shirts for collared button downs, go for a nice blazer instead of a denim jacket, and invest in a nice pair of shoes.[1]
- Go shopping with an adult and ask for their opinion on your selections. Look for clothing that is high quality and well made. Fast fashion, or trendy styles may look good in the moment, but it's a smarter move to invest in pieces that will last you longer than a few weeks.[2]
- Put some effort into your appearance by doing your hair, making sure your clothes are clean, and putting cologne or perfume on.
2Keep your living area clean and tidy. Messy living spaces can make you feel like you are living in a college dorm room, or a kid's room. Clean up the sink full of dirty dishes or the piles of laundry lying around your room or apartment. Reduce clutter by re-organizing your space to be more functional. Focus on presenting a clean, organized living space.[3]
3Find a mentor. A mentor is someone who gives help and advice to a less experienced person.[6] A good mentor will help you build your self confidence and self worth. They will teach you new skills or help you improve on the skills you already have, and act as a role model or someone you can look up to.
- Reach out to your guidance counselor at school, or to your community leaders. You can also look for a mentor in a family member or a close family friend.
- Look at programs like the Boys and Girls Club, which connects young people to role models and mentors in their community.[7]
4Learn a new skill. This could be cooking, driving, or even crocheting. Focus on building your self confidence by learning more about a skill or activity that interests you.
- Obtaining your drivers license is a big step to becoming more responsible and independent. You no longer have to depend on someone else, such as your parents, to drive you around or adhere to someone else's schedule when you need to get to a date or an important meeting.[8]
- Even if you decide not to get a car, having your license means you always have the option of renting a car for a trip or driving someone else's car as their designated driver after a night out.
- Getting better at cooking is a great way to gain more independence and become more confident as a person.[9]
- Start small and tackle small dishes like a sandwich for lunch or a stir fry for dinner. Look online at simple recipes that take under 30 minutes to prepare.[10] Offer to cook for your parents one night, or for a friend to show off your new skills. The more you practice cooking, the more confident you will become in the kitchen.
5Take control of your finances. This is a big one, but most adults have their finances under control and in order.
- Set up a meeting with a financial advisor to discuss smart ways to invest your money. Create a budget, broken down by month. Focus on putting as much money as possible into your savings account. This money could go to other very adult things like a car, a home, or a big trip.[11]
- Avoid splurging on clothing or other unnecessary items. This will show the adults in your life that you are serious about being responsible about how and when you spend your money.
- Taking control of your finances will also benefit you as a person and give you more self confidence in the company of other adults.
Part 2
Adjusting Your Attitude and Demeanor
1Use your manners. Say please and thank you, say excuse me in a crowded room and bless you when someone sneezes. Send thank you cards, call your mother back and chew with your mouth shut. Displaying good manners shows respect towards others, which will then make others respect you as an adult.[12]
2Take responsibility for your actions. If you get into an argument with someone, take responsibility for your part in the confrontation and apologize to that person. If you accidentally ding your parents' car on a night out, take responsibility for that action and tell them what happened. Owning up to your mistakes is a big part of being an adult, even if it means facing the consequences.[13]
3Don't be afraid of negative feedback, as long as it is constructive. A big part of being an adult is being willing to work on improving yourself, every day. Feedback from a teacher, a manager, or a peer can help you develop into a better adult, as long as it is constructive and not hurtful or insulting. Many adults face criticism in their work and at home. Handling the criticism with grace and openness shows you are a mature, confident person.[14]
- If you do receive negative feedback, focus on how you can improve your work based on that feedback. Don't overanalyze the negative comments or whine about the negative outcome. Instead, look at how you can use the feedback in a positive way to get better at your job or at your studies.
4Be confident, but not arrogant. Approach situations with confidence and purpose, especially if it has to do with your schooling or your job. But avoid acting stuck up or arrogant towards others. This will only alienate you from other people and lead to confrontation.[15]
- Being confident, rather than arrogant, will also allow you to consider other peoples' points of view and show that you can act as a good leader and role model for others.
Community Q&A
Sources and Citations
- ↑ http://jezebel.com/5916691/how-to-look-and-act-your-real-age
- ↑ http://www.bustle.com/articles/25514-7-ways-to-make-your-wardrobe-more-grown-up-after-collegeM
- ↑ http://www.healthyplace.com/blogs/buildingselfesteem/2013/09/behave-like-an-adult-build-self-esteem/
- ↑ https://www.wikihow.com/Organize-Your-Bedroom
- ↑ https://www.wikihow.com/Clean-a-House
- ↑ http://www.merriam-webster.com/dictionary/mentor
- ↑ http://www.bgca.org/Pages/index.aspx
- ↑ http://psychcentral.com/ask-the-therapist/2011/12/25/i-dont-feel-like-an-adult/
- ↑ http://psychcentral.com/ask-the-therapist/2011/12/25/i-dont-feel-like-an-adult/
- ↑ http://www.foodnetwork.com/recipes/packages/quick-fix-meals-30-minutes-or-less.html
- ↑ http://www.healthyplace.com/blogs/buildingselfesteem/2013/09/behave-like-an-adult-build-self-esteem/
- ↑ http://www.healthyplace.com/blogs/buildingselfesteem/2013/09/behave-like-an-adult-build-self-esteem/
- ↑ http://www.marcandangel.com/2007/08/17/what-is-adulthood-20-defining-characteristics-of-a-true-adult/
- ↑ http://www.marcandangel.com/2007/08/17/what-is-adulthood-20-defining-characteristics-of-a-true-adult/
- ↑ http://www.marcandangel.com/2007/08/17/what-is-adulthood-20-defining-characteristics-of-a-true-adult/
Article Info
Categories: Emotional Health and Well Being
In other languages:
Español: actuar como adulto, Italiano: Comportarsi da Persona Adulta, Português: Agir Como um Adulto, Русский: вести себя как взрослый, Deutsch: Sich wie ein Erwachsener benehmen, Français: te comporter comme un adulte, Bahasa Indonesia: Bersikap Seperti Orang Dewasa
Thanks to all authors for creating a page that has been read 245,472 times.


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Book: A Painful Gift: The Journey of a Soul With Autism
By: Duncan McGibbon
A Painful Gift: The Journey of a Soul With Autism
Christopher Goodchild Ill. Julie Lonneman publisher: DLT
The account of a life lived under God is a deeply fixed feature of spiritual writing. We have Augustine and the scope of life lived for the unconscious call of God who proves Himself ultimately irresistible. We have Rousseau and the testament of the natural man breaking the chains of illusion. Between the two most others can be ranged.
Christopher Goodchild's book is somewhat of a hybrid between the two. He writes well of his imperfections. Many are drawn into his moral censure, parents, adoptive parents, playmates, siblings, psychologists, social workers and girlfriends. As such he is more bitter than Augustine. Many are drawn to help him, as such he is luckier than Rousseau. His spiritual progress is largely charted through successive diagnoses of increasingly blameless syndromes.
The book is beautifully illustrated. There is an honest, rough piety in his self-appraisal. It may not be for all, but for specialists, there is a testament here.
For more information see: www.dltbooks.com/book_details.asp?bID=943&bc=7&sID=&Type=B&cp=2


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Mr. and Mrs. Ernest William Norman, Sr. of Comer, Georgia, announces the engagement of their daughter, Valerie Kyle Norman, to Jason Wayne Fortson, son of Mr. and Mrs. Jerry Wayne Fortson, of Colbert, Georgia.
Print-ready version
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The future bride is a 2001 graduate of Madison County High School, and is a senior at The University of Georgia. She is currently employed at The Urology Clinic.
Miss Norman is the granddaughter of the late Mr. and Mrs. Henry Pascall Kyle of Hampton, Virginia; and the late Mr. and Mrs. William Daniel Norman of Hack-ensack, New Jersey.
The future groom is a 1997 graduate of Madison County High School. He is currently employed with Gold Kist as a Poultry Grower.
Mr. Fortson is the grandson of Mr. and Mrs. James Cecil Fortson of Athens, Georgia; Mrs. Lucille Sartain of Athens, Georgia and the late Mr. Stewart Sartain.
The wedding is planned for 6:00 p.m. June 5, 2004 at Athens First United Methodist Church.
© 2017. All Rights Reserved. | Contact Us


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First Drive: 2018 Lexus LS 500 and LS 500h
High luxury sedan becomes more personal
By Nina Russin
The original LS sedan launched the Lexus brand in the US in 1989: since then the flagship has set technological and aesthetic standards for the rest of the automaker's line-up.
But while other models such as the GS, IS and most recently the new LC became sportier, more emotive cars, the LS remained conservative, appealing to owners who purchased those vehicles as chauffer cars as well as those who drove them. The new LS 500 and LS 500h that roll out later this year are sportier, more personal sedans.
Taking their cue from Akio Toyoda's promise to reinstall passion in the brand, engineers focused on two new V-6 engines as part of a new global luxury platform. The twin-turbo V-6 that replaces the naturally-aspirated V-8 on the gasoline powered model develops 416 horsepower and 442 pound-feet of torque, while the hybrid shares the same new direct injection V-6 as the new LC 500h.
Engineers moved the front wheels forward and engine back to create a front-mid-ship layout for better front-to-rear weight balance. An all-new ten-speed automatic transmission enhances fuel economy with large overdrive gears for steady-state cruising.
The sedan body has a slightly longer wheelbase, adding rear hip and legroom, but also sits lower to the ground for better high-speed performance.
The F-Sport model is available with a performance package that adds bigger brakes and enhanced steering dynamics.
Although Lexus has yet to announce pricing, it expects the base model to start at about $75,000, with the average transaction price for the LS 500 averaging $80,000 or less. Read the rest of this entry »
2017 Lexus ES 300h
Entry luxury sedan gets new standard safety technology
By Nina Russin
The ES 300 and ES 300h are the entry luxury members of the Lexus sedan family that also includes the sporty GS and high luxury LS series. Because the ES is approximately the same size as the Toyota Camry, some folks assume that the Lexus is a dressed-up version of Toyota's best-selling passenger car.
While both vehicles share the same 2.5-liter four-cylinder engine, continuously-variable automatic transmission and similar hybrid componentry, they have very distinct personalities. The Lexus has a two-inch longer wheelbase for more second-row passenger space. Suspension layouts and tire and wheel packages for the two cars are also different.
For 2017, Lexus adds some important active safety technology as standard equipment to the ES 300h as part of Lexus Safety System +, that was an option for 2016. It includes pre-collision with pedestrian detection, dynamic radar cruise control, lane departure assist and intelligent high-beam headlamps.
Base price for the ES 300h is $41,820 excluding the $975 destination charge. Options on the test car include blind spot monitoring with cross traffic alert, LED headlamps, Mark Levinson premium audio system with navigation and Lexus Enform, power trunk, interior trim package including wood accents, driver and passenger seat memory, heated and ventilated front seats, power rear sunshades, ambient lighting and power tilt-and-telescoping steering wheel, and a heated steering wheel.
Final MSRP is $49,775. Read the rest of this entry »
2017 Lexus GS 200t
Midsize sport sedan gets a turbo boost
By Nina Russin
The midsize Lexus GS has long been a favorite among driving enthusiasts, due to its exceptional front-to-rear balance, abundant power and solid steering response. Following a major redesign for the 2016 model year, the 2017 models add standard Lexus Safety System Plus: a suite of active safety features including pre-collision, lane departure alert and assist and dynamic radar cruise control.
Buyers can choose between the gasoline-electric GS 400h and two gasoline models: the GS 350 and turbocharged GS 200t. The V-6 model is available with all-wheel drive while the 200t is rear-wheel drive only.
An eight-speed automatic transmission is standard for both rear-wheel drive models, providing several large overdrive gears for enhanced fuel economy during steady-state cruising.
For those who can live without four-season capability, the turbocharged GS offers a couple of advantages: better fuel economy due to its lighter powertrain, and thanks to the smaller engine, even better front-to-rear weight balance.
Base price for the GS 200t is $46,310 excluding the $975 destination charge. Options on the test car include 18-inch alloy rims, Mark Levinson premium audio system, navigation with a 12.3-inch touchscreen and Lexus Enform and intuitive park assist, bringing the final MSRP to $50,070. Read the rest of this entry »
2017 Toyota Avalon Touring
Premium midsize sedan with enhanced active safety features
By Nina Russin
The Avalon is Toyota's flagship sedan: slightly larger than the midsize Camry, and targeted at customers wanting a premium driving experience. The first Avalon introduced in 1995 as the replacement for the Cressida did in fact share chassis components with the Camry, but since then the two vehicles have taken different paths, the newest Camry being edgier while the Avalon maintains a more conservative approach.
Buyers can choose between the gasoline model powered by a 268-horsepower V-6 engine and six-speed automatic transmission or a gasoline/electric hybrid model. Of the gas-powered versions, the upscale Touring model tested is the sportiest, with standard 20-inch alloy rims. Drivers can choose between Eco, Normal and Sport driving modes, adjusting the car's throttle mapping to suit their particular-needs.
This year, all Avalon models come standard with Toyota Safety Sense with pedestrian detection, adding pre-collision, autonomous braking with pedestrian detection, adaptive cruise control, lane departure warning and assist and automatic high beams to the sedan's roster of standard safety features.
Base price for the Touring grade is $37,650 excluding the $865 destination charge. Standard convenience features include keyless entry and start, dual-zone climate control, Entune premium audio with app suite, Bluetooth interface, satellite radio, leather upholstery, eight-way power driver's seat with memory, four-way power front passenger seat and Qi compatible wireless smartphone charging.
Options on the test car include special metallic pearl exterior coat and carpeted trunk mats, bringing the final MSRP to $39,134. Read the rest of this entry »
2018 Genesis G80 3.3T Sport
Mid-size luxury sedan gets a power boost
By Nina Russin
The G80 is the smaller of two luxury sedans Genesis produces. Now in its second year, the automaker has sweetened the deal with a Sport version powered by a 3.3-liter twin-turbocharged engine: the same V-6 available in the larger G90. The G80 Sport comes with an eight-speed shift-by-wire transmission and continuously damping control suspension that makes real-time adjustments based on road surface and driving style.
Priced at $56,225 including destination the model features unique exterior trim, 19-inch alloy rims and quad dark chrome exhaust tips.
A spacious interior features leather upholstery, micro-suede headliner, aluminum and carbon-fiber trim, plus all the accouterments one might expect from a mid-luxury sedan: premium audio system, heated and ventilated power front seats, heads-up display, wireless charging port, color LCD information display, large center stack touchscreen, automatic climate control and more.
The automaker's 10 year/100,000-mile powertrain warranty is its ace-in-the-hole. Read the rest of this entry »
2018 Honda Odyssey Elite
Best-selling minivan appeals to growing families
By Nina Russin
For years, the Honda Odyssey has been a dependable choice for growing families. Although the segment has decreased in size, minivans remain still an important player in the automotive universe due to their unique capabilities for this group of buyers. Honda's newest Odyssey should continue the model's leadership role, thanks to a more powerful engine, ten-speed automatic transmission boosting fuel economy and advanced active safety technology.
The Odyssey has grown significantly in size over the years: once built on the Accord platform and now sharing underpinnings with the Pilot crossover. But the newest model is as easy-to-drive, maneuver, load and unload as its predecessors. Twenty-two mile-per-gallon fuel economy helps parents stay within their budget, so the summer road trip remains part of the mix.
Power for the newest model comes from a 3.5-liter VTEC V-6 engine and ten-speed automatic transmission for the premium front-wheel drive grades. Variable cylinder management automatically shuts off fuel to half the engine cylinders when power demands are low to extend the car's range.
Base price for the Elite model tested is $46,670, excluding the $940 delivery charge. Honda loads the car up with all the safety, comfort and convenience features buyers are looking for so they don't have to wade through a laundry list of option packages. Final MSRP is $47,610. Read the rest of this entry »
2017 Jeep Compass Limited 4X4
Compact crossover with off-road capability
By Nina Russin
For 2017, Jeep replaces the now defunct Patriot with an all-new Compass: combining the former model's off-road capability with a more car-like appearance, ride and handling. In terms of size, the Compass sits between the smaller Jeep Renegade and larger Cherokee. Whereas Renegade styling veers more toward the Wrangler, the Compass bears greater similarity to the Cherokee and Grand Cherokee, with more rounded lines on the outside and a plush interior.
The North American version is available exclusively with Jeep's 2.4-liter naturally aspirated four-cylinder engine (diesel is available in other global markets). Buyers who opt for the off-road capable 4X4 model can choose between a six-speed manual or nine-speed automatic transmission.
The Limited is the most upscale trim level, appealing to buyers who want a premium feel and don't need the expanded off-road capabilities of the Trailhawk version. Base MSRP is $28,995 excluding the $1095 destination charge.
Options on the test car include two safety packages that add Xenon headlamps, lane departure warning, automatic high beams, brake assist, blind spot monitoring, rear part assist and rain sensitive wipers, navigation, Sirius XM Travel Link, a power liftgate, compact spare tire, nineteen-inch rims and all-season tires. Final MSRP is $34,260. Read the rest of this entry »
2017 Nissan Titan XD
Bridges the gap between light and heavy-duty pickups
By Nina Russin
Nissan calls the XD a niche vehicle that created its own niche, by bridging the gap between light and heavy-duty pickup trucks. Drivers who need more payload and towing capacity than a light-duty truck provides, but don't have the parking space or fuel budget for a heavy-duty truck can find a lot to love in the Titan XD.
Buyers can choose between a gasoline or Cummins turbo-diesel engine. The diesel option develops up to 555 peak horsepower as engine speeds as low as 1600 rpm, making it ideal for towing and hauling. The rear-wheel drive model tows up to 12,640 pounds, while the four-wheel drive truck tested has a 12,360-pound rating. Either way, the XD tows about 3,000 pounds more than its light-duty sibling: something that could make a critical difference when hooking up a large boat or trailer.
The Platinum Reserve model tested comes with a Class IV gooseneck hitch with integrated 4 pin/7 pin wiring harness-connector, trailer brake controller and trailer light check function, spray on bedliner, Utili-track tie down system, LED under-rail bed lighting, rearview and around-view monitors. Pricing starts at $61,960 excluding the $1195 destination charge. A bed utility package adds the Titan Box integrated storage system in the side walls of the cargo bed, an electronic tailgate lock and rear bed step, bringing the final MSRP to $63,905. Read the rest of this entry »
2017 Ford F-150 Raptor
Off-road racer is top tier at any speed
By Nina Russin
This year, Ford introduces an all-new version of its off-road race-ready Raptor, based on the F-150 light-duty pickup truck. Powered by an EcoBoost V-6 engine that delivers a whopping 450 horsepower and 510 lbs.-ft. of peak torque, the Raptor is a formidable competitor on any terrain.
To prove its mettle, Ford Performance entered a Raptor in the Baja 1000: the granddaddy of Mexican off-road SCORE races. It's a grueling test for any vehicle, with roaming cows, seas of loose sand, boulders and rattlesnakes all in a day's work. The Raptor placed third in its class, after which Greg Foutz and his team drove the car back to their shop in Phoenix, Arizona, almost 400 miles away.
What makes the Raptor even more amazing, and what distinguishes the 2017 model from the first-generation car, is how well it functions as a daily driver. Small but significant design changes such as the dropped side windows that lower the driver's sight-line to better spot low-profile cars, a more versatile, quieter interior make the Raptor a competent contender in the Monday-Friday 9-5.
The twin turbocharged V-6 engine gains three miles-per-gallon over the 2014 model and accelerates faster. The ten-speed automatic transmission on the 2017 model that replaces a six-speed gearbox on the 2014 truck does a better job of matching power needs to output, making for a smoother and more fuel-efficient ride.
Engineers utilized high-strength military grade aluminum alloy for the body to shave off 500 pounds compared to the outgoing model. In addition to improving gas mileage, the rigid body produces remarkably good steering feedback from the EPAS system, on par with vehicles having less suspension travel and lower centers of gravity. Drivers can select from three steering modes- normal, sport or comfort- depending on their needs.
Base price for the Raptor is $48,325 excluding the $1,195 destination charge. Options on the test car include a power sliding rear window, 360-degree camera, automatic temperature control, LED cargo box lighting, trailer brake control, trailer backup assist, remote start, voice-activated navigation, tailgate step, 17-inch forged alloy wheels, and a technology package with adaptive cruise control. Final MSRP is $64,420. Read the rest of this entry »
First Drive: 2017 Chevrolet Bolt EV
EV boasts extended range, versatility and connectivity features
By Nina Russin
Chevrolet has entered the EV world with both feet in, following up on the success of the second-generation Volt extended-range vehicle with the Bolt: a pure electric small crossover with 238-mile driving range according-to the manufacturer.
The Bolt doesn't have quite the interior space or driving range of the larger Volt since there is no gasoline engine in reserve, but its well-configured interior, enhanced connectivity and fun-to-drive character should hold lots of appeal for buyers who have been considering an electric car, but were deterred by pricier competitors, or vehicles with significantly less range.
EVs by their nature are rocket ships off the line, since electric motors develop peak power at very low speeds. The Bolt has the distinction of offering the most powerful electric motor in the segment: 150kW, making the car capable of sub-seven second zero-to-sixty acceleration.
Pricing for the base LT model starts at $37,495 before the federal rebate while the upscale Premier model starts at $41,780. The car becomes available in 48 states this August. Read the rest of this entry »


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7 months old should I be brushing her teeth?(5 Posts)
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Family of disabled girl vent fury over Disney on Ice ticket row
A disabled girl's family have claimed they were forced to buy an extra ticket for Disney on Ice because she was too young to qualify for a free ticket for her carer.
The SSE Arena said that only disabled children over the age of 14 can get a free ticket for their carer to attend a show.
Chelsea Webster, from Irvinestown, is nine, and her mum was told that she would have to buy a ticket if she wanted someone to accompany her disabled daughter.
The little girl has cerebral palsy and scoliosis, which is an abnormal twisting of the spine, and is confined to a wheelchair. She is also almost completely blind.
Her mum Lisa Nangle decided to take her to Disney on Ice at the SSE Arena in Belfast as a birthday treat yesterday as she turns 10 on Friday.
The Disney on Ice Worlds of Enchantment tour features characters from some of Hollywood's biggest children's movies performing some of Chelsea's favourite songs.
Chelsea's carer Jenny Castle explained: "She is blind but she can make out lights and she loves the music so they decided to take her to see the show. I bought her the sing-a-long Frozen last Christmas and she just adores it so this was a special treat."
Chelsea's mum Lisa bought tickets for her daughter and her partner Peter. After speaking to other parents of disabled children, she believed that she would get a companion ticket for free.
However, when she contacted the SSE Arena, she was told that tickets for carers are only given free of charge to disabled children over the age of 14.
As Chelsea is nine, she did not qualify and Lisa was forced to pay for the extra ticket as she did not want to disappoint her daughter. The family saw the show but it cost a total of almost £80.
A spokesperson for the SSE Arena confirmed yesterday that it is their policy to charge for tickets for carers of any disabled children below the age of 14.
They explained that as all children below the age of 14 should be accompanied by an adult anyway, it is their policy to charge parents or carers of anyone below that age.
As those over the age of 14 could attend an event alone, they do not charge the carers of disabled children over this age.
Jenny explained: "We're all annoyed about this. The money doesn't matter but it's the principle. In four years time, she could go and her carer could go for free. It seems ridiculous."
"Chelsea is in her own wheelchair so she doesn't take up a seat. She's been to other shows elsewhere before and they haven't had this issue.
"I want to raise this issue for the parents of other disabled parents, especially those who can't afford to pay for that extra ticket."
Belfast Telegraph


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Bio & Incident Details
Age: 42
Tour: Not available
Badge # 1871
Military veteran
Cause: Vehicular assault
Incident Date: 6/4/1985
Weapon: Automobile
Offender: Sentenced to life
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Officer Johnnie Corbin was intentionally run down by a subject after issuing him a $4.00 street cleaning violation.
Officer Corbin was driving a tri-car at the time and had driven further down the street when the suspect got into his car and intentionally drove into the vehicle at a high rate of speed. The man then got out of his car and began kicking Officer Corbin until a bystander subdued the man and held him for authorities.
The subject was sentenced to life in prison. In March of 2014 the 72-year-old subject was denied parole for the sixth time. His next parole hearing will be in February of 2018.
Officer Corbin was a U.S. Marine Corps veteran. He was survived by his mother and daughter.


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Rooms, services Chalet Hotel Senger Heiligenblut is pleased to host travellers looking to spend a few pleasant days in Austria. The hotel is welcoming all guests in Heiligenblut am Großglockner with 16 comfortable rooms to stay in. Since the hotel has an own restaurant, you may also try fine local meals on the spot. If necessary, parking is available nearby. Table tennis and bike rental opportunities will also be available nearby to help you spend your leisure time actively. The café or the bar can be an ideal place for a pleasant evening talk or a meeting. Your valuables may be the safely secured in the safe. Wireless Internet connection (WiFi) is available at the hotel, enabling portable devices and smartphones to go online. If you wish to learn more about the exact scope of services provided by Chalet Hotel Senger Heiligenblut (including those available for an extra fee) or about the equipment of the rooms, you can find the complete list on the information sheet below.
Payment Depending on the selected date, room and price, you may need to provide credit card guarantee or advance bank card payment to finalize your reservation.
Arrival, opening hours The earliest check-in time to your room is 14:00, the latest check-out time from your room is 11:00. The personnel can speak English and German languages.
Chalet Hotel Senger Heiligenblut rooms Rooms
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Pet friendly (10 €/night), Garden, Bar, Cafe, Elevator, Safe deposit box
Own restaurant
Bathrobe, Hairdryer


text:
"That skinny Indian teenager has that mysterious something that comes along once a generation. He is one of those rare chefs who is simply born. He is an artist."
And so begins the rise of Hassan Haji, the unlikely gourmand who recounts his life's journey in this charming audiobook. Lively and brimming with the colors, flavors, and scents of the kitchen, The Hundred-Foot Journey is a succulent treat about family, nationality, and the mysteries of good taste.
Born above his grandfather's modest restaurant in Mumbai, Hassan first experienced life through intoxicating whiffs of spicy fish curry, trips to the local markets, and gourmet outings with his mother. But when tragedy pushes the family out of India, they console themselves by eating their way around the world, eventually settling in Lumière, a small village in the French Alps.
The boisterous Haji family takes Lumière by storm. They open an inexpensive Indian café opposite an esteemed French restaurant - that of the famous chef Madame Mallory - and infuse the sleepy town with the spices of India, transforming the lives of its eccentric villagers and infuriating their celebrated neighbor. Only after Madame Mallory wages culinary war with the immigrant family does she finally agree to mentor young Hassan, leading him to Paris, the launch of his own restaurant, and a slew of new adventures.
The Hundred-Foot Journey is about how the hundred-foot distance between a new Indian kitchen and a traditional French one can represent the gulf between different cultures and desires. A testament to the inevitability of destiny, this is a fable for the ages - charming, endearing, and a joy to listen to.
Richard C. Morais, author of The Hundred-Foot Journey, is a contributing editor at Barron's in New York. An American raised in Switzerland, he was stationed in London for seventeen years, where he was Forbes' European bureau chief.
"Outstanding! A completely engaging human story heavily larded with the lushest, most high-test food porn since Zola. Easily the best novel ever set in the world of cooking—and absolutely thrilling from beginning to end. I wished it went on for another three hundred pages."—Anthony Bourdain, New York Times bestselling author of Kitchen Confidential
"A gorgeous novel, vivid and intimate, tracing a journey from kitchen to kitchen, from culture to culture, with a perfect touch."—Susan Orlean, New York Times bestselling author
"Richard C. Morais conjures a richly woven tapestry of exotic sights, smells, and tastes that transports the reader to a world of epicurean delights. This is a charming, deeply felt novel that questions, and ultimately celebrates, the twists and turns of an authentically lived life."—Elin Hilderbrand, New York Times bestselling author
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Great details & writing in a flawed story
- Marci
Amazed that this is fiction....
- Janie