text:
University Park, Pa. -- A Neuroscience Institute, dedicated to teaching, research and service across the broad array of neuroscience-related disciplines from molecular and cellular research to studies on human behavior, has been added to Penn State's Huck Institutes of the Life Sciences.
A Biotechnology Institute and an Institute for Genomics, Proteomics and Bioinformatics already exist as part of the Huck Institutes. Like those institutes, the Neuroscience Institute will bring together faculty members and students from throughout Penn State. Colleges currently planning to participate in the Neuroscience Institute include Agricultural Sciences, Engineering, Health and Human Development, the Liberal Arts, Medicine and Science.
"The Huck Institutes' objective is to move forward in the life sciences by supporting the best and most innovative ideas and people, regardless of their academic home and discipline," said Channa Reddy, director of the Huck Institutes. "While the Neuroscience Institute is now a virtual organization, the new Life Science Building-2, when completed, will connect neuroscientists in different disciplines and locations physically even as we connect them conceptually through the Huck Institutes."
Bernhard Luscher, associate professor of biology and of biochemistry and molecular biology at University Park, is an interim co-director of the cross-campus Neuroscience Institute. Thomas Uhde, professor and head of the Department of Psychiatry, also is a co-director. Uhde directs neuroscience research, patient care and outreach at Penn State Milton S. Hershey Medical Center and the College of Medicine.
At University Park, some of the neuroscience activities now are housed on the second floor of the Life Sciences Building-1 where the Huck Institutes office is located. However, a new Life Sciences Building-2 also is planned, which will house neuroscience activities. The initial $40 million program budget provides for a building with 54,000 assignable square feet. The building will contain new research laboratories, multi-disciplinary core facilities and videoconference rooms.
Core facilities planned for the new building include Magnetic Resonance Imaging (MRI) and Biophotonics facilities. A new faculty member scheduled to join the bioengineering department this summer, Andrew Webb, already is working with Michael B. Smith, Penn State Hershey MRI research facility director, to set up an MRI facility for animal studies at University Park. The facility at Hershey handles both animal and human subjects. The Department of Psychology at University Park is working on an MRI facility for human imaging studies, and the Neuroscience Institute is looking into partnering with Mount Nittany Medical Center, which also has an MRI facility for human studies.
Ahmed Heikal from the Department of Bioengineering and Steven Benkovic from the Department of Chemistry are taking the lead in building the Biophotonics facility, which will be housed in the basement of Life Sciences Building-2. The Biophotonics facility will aid in research to identify and characterize protein-protein interaction networks.
In addition to the new building and core facilities, plans also call for 30 to 40 more neuroscience faculty members to be hired at the College of Medicine and at University Park over the next decade.
Karin Foley, associate dean in the Eberly College of Science, and Jay Moskowitz, vice dean for the research and graduate studies in the College of Medicine, presented a report to Eva J. Pell, vice president for research and dean of The Graduate School, on behalf of the University-wide Neuroscience Advisory Committee. The report contained the recommendation to create the Institute and noted, "The neurosciences are one of the most rapidly growing and challenging areas of the life sciences. They account for a substantial proportion of federal funding in biomedicine reflecting the considerable impact of neurological and psychiatric diseases on society. A substantial program in neuroscience research and education is essential for a major research university."


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Release Date: 2011 |
Album Rating: 3.5I actually kinda really like this, I'm debating bumping the review rating.
oh shit
that album cover is hilariously bad
This sounds kinda sweet.
Digging: Gamma Ray - Land of the Free
Album Rating: 3.5i dont know, i kind of prefer it to the overtly serious album covers most thrash bands try to have these days
and yeah hawks you would probably dig this. it's still pretty good, they just have minor kinks to work out
You need to break up those sentences, man. There are only 6 in the whole review. It makes it a nightmare to read.
sweet cover gonna check
Album Rating: 3.5I don't really think it's that hard to read? As long as it's grammatically correct. And yes KILL you would probably dig some of this.
this album cover is awesome. Reminds me of the 80s. What u think KILL? Throwback??
Maybe "a nightmare to read" was too strong a phrase, but such long sentences reduce the review's clarity and make the writing less effective. It's certainly not a bad review by any means, but it could be a lot easier to read.
Album Rating: 3.5Hmm well I appreciate you looking it over and commenting on that, I'll try and switch it around a bit. Thanks!
Spirit, whats the vocals like on this? Are they harsh or clean?
Album Rating: 3.5They are harsh
Felt this album sagged around the middle a bit
This ain't too shabby, surprised not too many ratings and views for this.
Digging: Beastmilk - Climax
Album Rating: 3.5I am too kinda. Glad to see your rating.
Bands: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

subset: commoncrawl


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Hi there I copy all my stuff from my ftp to my local machine (mamp pro)
I export the MysQL database and replace the old URL to the new one
( http://rammler.de/demo/joos/ to http://bernd.local:8888/wordpress/joos/ )
UPDATE wp_options SET option_value =
replace(option_value, 'http://rammler.de/demo/joos/', 'http://bernd.local:8888/wordpress/joos/');
UPDATE wp_posts SET post_content =
replace(post_content, 'http://rammler.de/demo/joos/', 'http://bernd.local:8888/wordpress/joos/');
UPDATE wp_posts SET guid =
replace(guid, 'http://rammler.de/demo/joos/', 'http://bernd.local:8888/wordpress/joos/');
And I change the config.php
But now when I type the new URL http://bernd.local:8888/wordpress/joos/ – the browser jump to http://bernd.local/wordpress/joos/ and this didnt work, cause the port is missing.
How can i fix this?
Big THX, Bernd
Hey Bernd,
Unfortunately we aren't really able to support getting your wordpress installation set up on either live servers or local servers. Your best bet is to check with the Mamp forums or the WordPress forums.
Hi Devin,
of course, I understand you, but I think this isn't a wordpress or Mamp problem, cause I do this several times – on the same way. I think it is the theme, or the theme has problems with the :8888 Port. I try ;-)
my mistake … sorry
Hi Rammler,
instead of working manually, searchreplacedb2 helped me to move my installation a couple of times. Check it out on: http://interconnectit.com/124/ (Purchase code hidden if logged out) -databases/
Apart of that, the browser jumping to your original URL sounds a little bit like a cache issue. Try to delete all cache files from any caching plugin you use.
The topic 'Moving from WP Installation to localserver didnt work, maybe you have a solution' is closed to new replies.


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Karcher Vacuum Cleaner Soft Brush Pad Stock Number: ES556616
Will this part fit my Appliance?
Vacuum Cleaner Soft Brush Pad
If your vacuum cleaner appliance is in need of a new soft brush pad in order to clean those hard to reach areas in your house, look no further than eSpares for a replacement. This is a genuine spare part for select Karcher vacuum cleaners. See the list of appliances to ensure compatibility.
This is Karcher spares reference: 6.959-032.0
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text:
Sterling went in late on Valencia with a reckless lunge down near his own corner flag, with the United man springing to his feet to grab his opponent around the neck.
|MATCH REPORT: Rooney & Lambert strike but Three Lions falter in Miami
Neither man will be suspended for any World Cup matches, but it will provide both managers with headaches with the tournament just over a week away.
Sterling, 19, had only been introduced as a 65th-minute substitute on the evening, but rather than impress boss Roy Hodgson he will have only prompted questions about his temperament.
Earlier on, Alex Oxlade-Chamberlain had been withdrawn with an injury following a challenge with Carlos Gruezo.
The Arsenal man missed much of the previous Premier League season through injury but was fit enough to walk from the pitch, albeit gingerly.
He had been in impressive form up until that point, providing several energetic runs to give England an outlet in the face of pacey Ecuadorian attacks.
England's Group D opponents Italy were also in action on Wednesday, but could only muster a 1-1 draw with Luxembourg.


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Canadian safety investigators said Tuesday there's no evidence that the derailed oil train that flattened a small Quebec town was sabotaged.
Two more bodies were found Tuesday, raising the death toll to 15 after the runaway train carrying crude oil slipped from its moorings early Saturday, speeded almost 7 miles down a steep grade, derailed and exploded in the town of Lac-Mégantic.
About three dozen other people remained unaccounted for.
Authorities said the cause of the incident still wasn't known, but they contested the assertion of Ed Burkhardt, chairman of the parent company of Montreal, Maine & Atlantic, the railway that operated the train, that "we have evidence" that it had been tampered with.
Quebec police Capt. Michel Forget said Tuesday that police had "discovered elements" that had led them open a criminal investigation. He said terrorism wasn't suspected and cautioned that "criminal negligence might be one of the leads we are looking at," as opposed to sabotage or active tampering.
Authorities announced the criminal probe Monday, saying more than 100 officers were involved.
Ed Belkaloul, manager of eastern rail operations for the Canadian Transportation Safety Board, also said at a news conference Tuesday that investigators had no evidence of sabotage and added that Burkhardt's company hadn't offered them any. Transportation authorities said Monday that the locomotive suspected of causing the derailment had been inspected just the day before the incident, on Friday, and was found to have no defects.
For the first time, TSB investigators gave a broad timeline of events overnight Friday and early Saturday.
The train, comprising 73 rail cars, all but one of them carrying crude oil, was parked for the night in the town of Nantes when a fire was reported shortly before midnight, TSB investigator Donald Ross said at a briefing for reporters. He said firefighters extinguished the blaze.
That fire is the focus of a dispute between the railway and investigators. Burkhardt said firefighters might have been responsible because they shut down the locomotive to put out the fire — and possibly turned off the brakes.
But Patrick Lambert, the Nantes fire chief, told The Globe and Mail of Toronto that his crew was following standard procedures dictated by Montreal, Maine & Atlantic and was told it could leave the scene by the railway. He angrily said he would "clear this all up" in the next few days.
What isn't in dispute is that by shortly before 1 a.m., the fire crew and a railway employee who had responded to the fire had left the scene. That's when the train is believed to have started rolling downhill about 7 miles toward Lac-Mégantic.
The slope of the track along that stretch is about 1.2 percent — which is relatively steep — and the train eventually raced well past the authorized speed limit, Ross said. At some point, "the locomotive detached from the rest of the train and carried through the rest of the town and out the other side, approximately six-tenths of a mile," he said.
Rail dispatch crews had no notice that the potential fireball was hurtling toward Lac-Mégantic because the train was traveling along a secondary line — that is, not one of major lines that serve cities like Montreal — and had no warning system.
"This area is not equipped with the type of signal systems that would even show to a rail traffic controller that something was moving on the territory that they hadn't authorized," Ross said.
Evacuees returning home
The white-hot fire continued burning through the weekend, forcing the evacuations of about 2,000 area residents and hampering investigators' access to the scene.
The fire was finally declared under control Tuesday, and about 1,200 residents of two neighborhoods were being allowed to return home.
The remaining 800 or so were still prohibited from returning home because they live in or near the center of town, the area hardest hit by the explosions, the Canadian Broadcasting Corp. reported.
"It's tough, but we'll live through it," Denis Couture, one of those allowed to go home, told The Montreal Gazette.
Ticking off the names of business that had been destroyed, he said: "We'll rebuild. There'll be another Dollarama. There'll be another Musi-Cafe bar. You just wait and see.
"We'll never replace what was there, but we will rebuild, and we'll keep on living."


text:
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Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). Additionally we are shipping Protein Phosphatase 4, Regulatory Subunit 2 Antibodies (44) and Protein Phosphatase 4, Regulatory Subunit 2 Proteins (4) and many more products for this protein.
PPP4R2 affects the survival of neuronal cells in response to DNA damage.
PP4R2, a regulatory subunit of PP4 (show ANXA5 ELISA Kits), mediates the DNA damage-dependent association between RPA2 (show RPA2 ELISA Kits) and the PP4C (show PPP4C ELISA Kits) catalytic subunit.
A three-protein PP4 phosphatase complex in mammalian cells, containing PP4C, PP4R2, and PP4R3beta, specifically dephosphorylates ATR-mediated gamma-H2AX generated during DNA replication.
Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair (By similarity). Mediates RPA2 dephosphorylation by recruiting PPP4C to RPA2 in a DNA damage- dependent manner. RPA2 dephosphorylation is required for the efficient RPA2-mediated recruitment of RAD51 to chromatin following double strand breaks, an essential step for DNA repair (By similarity).
serine/threonine-protein phosphatase 4 regulatory subunit 2-A
, protein phosphatase 4, regulatory subunit 2
, serine/threonine-protein phosphatase 4 regulatory subunit 2


text:
I am looking for a place that sells Cuban Chop-Chop (chopped up grilled chicken with spices, rice, and served with tasty sauces, typically a mustard curry sauce) - also known as Miami-style Chicken Chop or Cuban Chicken Chop.
Is there any place in the Boston area that sells this? Typically it's sold at fast-food like settings.
I have a huge craving for it - some of my family lives in Miami, where it is ubiquitous - and surprisingly I've been able to find it in many different cities/places but never in Boston.


text:
WASHINGTON -- There are no specific threats of terrorist attack in this country that are related to the new year, but the FBI still intends to remain on alert, Attorney General Janet Reno said Thursday.
Asked if there were any domestic threats similar to the attacks on Americans abroad allegedly being planned for New Year's gatherings by 13 people arrested in Jordan recently, Reno told her weekly news conference:
''We have no specific information concerning specific attacks. We must always be concerned about the possibility of an attack and take every reasonable step that we can.''
She said common sense prevented her from publicly outlining in detail the precautions taken by her department. But, she said, ''We must be vigilant, and the FBI is working with colleagues around the world to make sure that we are vigilant and as prepared as we possibly could be for any eventuality.''
Reno plans to stay in Washington. Aides said she will spend the New Year's weekend either at the Justice Department or at her apartment just blocks away.
All 56 FBI field offices will be staffed by a special Y2K command post around the clock from 6 a.m. on Dec. 31 through 6 p.m. on Jan. 3, according to law enforcement officials, who requested anonymity.
At FBI headquarters, three separate teams will staff the Strategic Information and Operations Center -- a windowless, 35-room command post covering nearly the area of a football field on the fifth floor.
One team will be on watch for incidents of terrorism directed at Americans at home or abroad, officials said. Another team, from the FBI's National Infrastructure Protection Center, will keep track of the nation's electronic networks for signs of computer attacks. A third team of Justice Department managers will oversee the department's own internal computers.
The department's budget contained funds for 10 to 12 computer squads that could be dispatched to investigate any sign of criminal hacking activity.
The FBI already has circulated to thousands of state and local police agencies an intelligence report entitled ''Project Megiddo'' describing hate or apocalyptic groups or lone wolf members of them who attach special significance to the year 2000.
The research report, named after an ancient battleground in Israel cited in the Bible's New Testament as the site of a millennial battle between forces of good and evil, examines ideologies ''which advocate or call for violent action beginning in the year 2000.''
''Such ideologies motivate violent white supremacists who seek to initiate a race war; apocalyptic cults which anticipate a violent Armageddon; radical elements of private citizen militias who fear that the United Nations will initiate an armed takeover of the United States and subsequently establish a One World Government, and other groups or individuals which promote violent millennial agendas,'' the FBI said.
The report also outlines indicators of potential violence, possible preparations for violence, like stepped-up physical training or stockpiling of arms, and possible targets of millennial extremists.
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Don't miss out on a lower price on this property
Get an overview of this hotelJerusalem aparthotel in Jerusalem City Centre, walk to Jerusalem Great Synagogue
Popular property highlights
Located in Jerusalem City Centre, this aparthotel is within a 10-minute walk of Zion Square, Jerusalem Great Synagogue, and Mamilla Mall. Mahane Yehuda Market and Tower of David Museum of the History of Jerusalem are also within 1 mi (2 km).
Property Features
This smoke-free aparthotel features a nightclub, a 24-hour business center, and self parking. WiFi in public areas is free. Additionally, concierge services, dry cleaning, and laundry facilities are onsite.
Room Amenities
All 43 apartments provide kitchenettes with refrigerators, plus free WiFi and LED TVs with satellite channels. Other amenities available to guests include sitting areas, first-run movies, and premium bedding.Information missing or incorrect? Tell us!Opens in a new window
Hillel 11 Hotel
Property Amenities
Property Amenities
Public areas are equipped with complimentary wireless Internet access. A 24-hour business center is on site. For a surcharge, a roundtrip airport shuttle (available 24 hours) is offered to guests. This Jerusalem aparthotel also offers a nightclub, a terrace, and tour/ticket assistance. Onsite parking is available (surcharge). A total renovation of this property was completed in January 2013.
Hillel 11 Hotel is a smoke-free property.
- Express check-in
- Elevator/lift
- 24-hour front desk
- Express check-out
- Tours/ticket assistance
- Year Built 2013
- Dry cleaning/laundry service
- Free WiFi
- Self parking (surcharge)
- Babysitting or childcare (surcharge)
- Smoke-free property
- Nightclub
- Safe-deposit box at front desk
- Terrace
- Luggage storage
- Hair salon
- ATM/banking
- Breakfast available (surcharge)
- 24-hour business center
- Concierge services
- Gift shops or newsstand
- Airport transportation
- Laundry facilities
- Number of floors - 5
- Number of buildings/towers - 1
- Airport transportation (surcharge)
Family Friendly Amenities
- Family Hotel
- Free Wi-Fi
- Kitchenette
- Laundry facilities
- Babysitting or childcare (surcharge)
- In-room childcare (surcharge)
- Refrigerator
- Cribs/infant beds (complimentary)
Available in all rooms: Free WiFi
Available in some public areas: Free WiFi
Self parking (surcharge)
Room Amenities
- Premium bedding
- Separate sitting area
- Air conditioning
- Phone
- Kitchenette
- Free bottled water
- Refrigerator
- Coffee/tea maker
- Daily housekeeping
- Turndown service
- Free toiletries
- In-room massage available
- Hair dryer (on request)
- In-room childcare (surcharge)
- In-room safe
- Blackout drapes/curtains
- Satellite TV service
- Free WiFi
- Down comforter
- First-run movies
- Pillow menu
- Free cribs/infant beds
- Rollaway/extra beds (surcharge)
If you have requests for specific accessibility needs, please note them at check-out when you book your room.
Property Policies
Minimum check-in age is 21
Special check-in instructions:
Check-out time is 11 AM
Payment types
Children and extra beds
- Children are welcome.
- Rollaway/extra beds are available for ILS 25 per night.
- Free cribs (infant beds)!
- Pets stay free
You need to know
Extra-person charges may apply and vary depending on property policy.
- No onsite parking is available.
- All citizens of Israel will be charged the national value-added tax
- Resort fee
Optional extras
- Breakfast fee: ILS 65 per person (approximately)
- Airport shuttle fee: ILS 65 per person (one way)
- Self parking fee: ILS 50 per day
- Rollaway bed fee: ILS 25 per night
Property Name
- Hillel 11 Residence
- Hillel 11 Residence Apartment
- Hillel 11 Residence Apartment Jerusalem
- Hillel 11 Residence Jerusalem
- Hillel 11 Hotel Jerusalem
- Hillel 11 Hotel
- Hillel 11 Jerusalem
- Hillel 11
We should mention
A resort fee is included in the total price displayed.


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Shortcut Drainage
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Shortcut drainage from summit. We left bikes at low point in trail in the upper left part of pic, followed drainage to river and crossed river. We travelled alongside river for 400 m until found South drainage off Romulus.
Drainage had several rockbands which we bypassed on the right side slopes through the trees. Oct/08
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Mount Romulus (Mountain/Rock)
Bill Kerr's Image Gallery
Mount Romulus Alternative Shortcut Scramble -South Drainage (Route)
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Lat/Lon: 50.78900°N / 114.993°W
Object Title: Shortcut Drainage
Image Type(s): Alpine Climbing


text:
BLINCK-A diagnostic algorithm for skin cancer diagnosis combining clinical features with dermatoscopy findings
Keywords: melanoma; skin cancer; diagnostic algorithm; BLINCK; primary care;
Citation: Bourne P, Rosendahl C, Keir J, Cameron A. BLINCK-A diagnostic algorithm for skin cancer diagnosis combining clinical features with dermatoscopy findings. Dermatol Pract Conc. 2012;2(2):12. http://dx.doi.org/10.5826/dpc.0202a12.
History: Received: October 30, 2011. Accepted: February 20, 2012. Published: April 30, 2012.
Copyright: ©2012 Bourne et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Funding: None.
Competing interests: All authors declare no conflict of interest with regards the preparation or writing of this paper. They have not accepted from a sponsor, pharmaceutical company or other organization any funds for research, consultancy fees, fellowship/research/education grants, nor hold any stock or shares in any entity that may gain financial benefit or detriment as a result of the deliberations set out in or the conclusions of the study.
Corresponding Author: Peter Bourne, , Skin Cancer Clinic of Toowoomba, Suite 10, 9 Scott St, Toowoomba, Queensland 4350, Australia. Tel. 07 46 130333; Fax. 07 46 130055.Email: email@example.com
Background: Deciding whether a skin lesion requires biopsy to exclude skin cancer is often challenging for primary care clinicians in Australia. There are several published algorithms designed to assist with the diagnosis of skin cancer but apart from the clinical ABCD rule, these algorithms only evaluate the dermatoscopic features of a lesion.
Objectives: The BLINCK algorithm explores the effect of combining clinical history and examination with fundamental dermatoscopic assessment in primary care skin cancer practice.
Patients/Methods: Clinical and dermatoscopic images of 50 skin lesions were collected and shown to four primary care practitioners. The cases were assessed by each participant and lesions requiring biopsy were determined on separate occasions using the 3-Point Checklist, the Menzies method, clinical assessment alone and the BLINCK algorithm.
Results: The BLINCK algorithm had the highest sensitivity and found more melanomas than any of the other methods. However, BLINCK required more biopsies than the other methods. When comparing diagnostic accuracy, there was no difference between BLINCK, Menzies method and clinical assessment but all were better than the 3-Point checklist.
Conclusions: These results suggest that the BLINK algorithm may be a useful skin cancer screening tool for Australian primary care practice.
Most GP skin cancer training courses in Australia encourage beginners to use dermatoscopy algorithms when deciding if a lesion requires biopsy to exclude skin cancer. Indeed, the ability to recognise dermatoscopic criteria correctly and apply a dermatoscopic algorithm is often seen as the sine qua non of excellence in primary care skin cancer practice.
The benefits of using a scored "dermatoscopy-only" algorithm are well documented [1,2]. However, this approach does not score often useful clinical information such as history of lesion change, the "ugly duckling" sign [3,4] and even the patient's own instinct regarding the lesion. The authors feel that a more "holistic" diagnostic approach, where these clinical aspects are also scored, may reduce the chances of the student missing less obvious skin cancers.
We performed a retrospective analytical trial to see if a new algorithm, incorporating clinical as well as dermatoscopic criteria, was any different to the three methods commonly used in Australia primary care practice to diagnose skin cancer. The new algorithm, BLINCK, was developed and compared to two "dermatoscopy-only" algorithms, (the 3-Point Checklist and the Menzies method), and clinical assessment alone. The BLINCK algorithm was designed as an assessment tool for primary care skin cancer clinicians and does not require the user to be an "expert" in dermatoscopy. In contrast to most existing algorithms, the distinction between melanocytic and non-melanocytic [5] lesions is not necessary and both pigmented and non-pigmented lesions may be assessed.
The acronym, BLINCK, refers to six questions that should be asked when assessing a skin lesion and includes both clinical and dermatoscopic features. B – Benign: Is the lesion immediately recognisable as a common benign tumour, on clinical and dermatoscopic examination, with other similar lesions being present on that part of the body, e.g., typical solar lentigo, seborrheic keratosis, haemangioma or dermatofibroma? If 'yes,'no further action is required. If 'no,' then proceed to the following four questions. L – Lonely: Is this lesion, clinically and dermatoscopically, the only one of its type on that region of the body, i.e., an "outlier" or "ugly duckling"? 'Yes' scores 1. I – Irregular: For pigmented lesions, is the lesion dermatoscopically irregular, that is, does it have an asymmetrical pigmentation pattern and more than one colour? For non-pigmented lesions, is there an irregular vascular pattern? 'Yes' scores 1. N – Nervous: Is the patient nervous or concerned that this particular lesion may be a skin cancer? (This excludes the "generally anxious" patient or patients with hypochondriasis). C – Change: Does the patient, or another observer, feel that the lesion is changing? (Note that only a total score of 1 can be given if either or both of these last two questions are answered 'yes.') K – Known clues Does the lesion definitely have any one of the following dermatoscopic "clues" to malignancy?
- Atypical network-unmistakable variation in thickness of network line
- Pseudopods or streaks-segmental
- Black dots, globules or clods-irregular and peripheral
- Eccentric structureless zone
- Blue or grey colour-irregular distribution
- Vessels-1. Polymorphous; 2. finely focused and arborizing; 3. glomerular (coiled) shaped
- Acral lesions-1. parallel ridge pattern; 2. diffuse irregular brown/black pigmentation
'Yes' to any one of these scores 1 (maximum score of 1). A total score of 2 or more out of 4 requires biopsy.
To compare BLINCK with the other diagnostic methods a pilot trial was conducted using images of skin lesions typically seen in Australian primary care skin cancer practice. From June 1 to July 6, 2009, all skin lesions consecutively excised to exclude skin cancer were recorded by an experienced skin cancer doctor, (A.C.), working in a dedicated skin cancer practice in Brisbane, Australia. Clinically obvious basal cell carcinomas which could be easily diagnosed without dermoscopy were not included in the collection set. High quality clinical and dermatoscopic photographs of 50 skin lesions were obtained, (non-polarised dermatoscopic images taken with a non-polarised Dermlite Foto attachment, or Dermlite Fluid dermatoscope, (3Gen, LLC), and Canon D40 digital camera, (Tokyo, Japan). Written patient consent was obtained in every case and any history of lesion change or patient concern was documented, as well as whether the lesion was thought to be an "ugly duckling" by the original examiner. As common lesions such as the dermatofibroma, seborrhoeic keratosis and congenital naevus sometimes pose a diagnostic challenge for inexperienced clinicians, an example of each, seen during the collection period, was included in the set of 50. These three cases were assessed as being obviously benign by A.C. and not biopsied. As well, a flat naevus that was unchanged on sequential digital monitoring was included in the set without biopsy. Histopathological examination of the other 46 lesions revealed 19 to be skin cancers with nine being melanomas (eight in situ and one invasive). Figures 1 and 2 show an example of a melanoma case from the trial.
Figure 1. Despite being dermatoscopically bland, this lesion had changed and was "lonely," scoring 2 in the BLINCK method and mandating biopsy. Histopathology is shown demonstrating melanoma in situ. A: Clinical view. B: Macro view. C: Dermatoscopic view. [Copyright: ©2012 Bourne et al.]
Figure 2. Dermatoscopic view. A: Histology slide 1. B: Histology slide 2. C: Histology slide 3. [Copyright: ©2012 Bourne et al.]
Four primary care clinicians, (three GPs and a clinical nurse), with varying levels of dermatoscopic experience, were asked to review the photographs and select which lesions were suspicious for malignancy, hence requiring biopsy. This assessment was done on four occasions, each time using a different diagnostic approach. The following methods were used in this order.
- 3-Point Checklist-Only dermatoscopic images were shown.
- Menzies method-Only dermatoscopic images were shown.
- Clinical assessment alone-Only clinical images were shown.
- BLINCK-Dermatoscopic and clinical images were supplied as well as information regarding reported lesion change, "ugly duckling" sign or patient concern as recorded by original examiner.
The clinicians received prior instruction on the use of the three algorithms, and Excel answer sheets for each method listed the various criteria used in that algorithm. The clinicians were asked to decide if these criteria were present or not and the spreadsheet was used to calculate the results. The clinician's response for each case was compared to the correct diagnosis and graded as true positive, false negative, false positive or true negative. The number of cancers and melanomas correctly detected and the number of biopsies indicated for each clinician and each method were also recorded (Table 1).
Table 1. True and false positives and negatives for the four methods by the four clinicians with sensitivity, specificity, melanomas found and biopsies indicated.
Four clinicians using four methods resulted in 16 contingency tables for sensitivity and specificity. As two of the methods related only to pigmented lesions, (3-Point and Menzies), the five non-pigmented specimens in the set of 50 were excluded from the contingency tables for these methods. Specificity, sensitivity and diagnostic accuracy were calculated according to standard formula. Analysis of variance (ANOVA) was used with the LSD test, (least significant difference test), to detect differences between clinicians and methods. A P-value of Statistica software package for statistical analysis.
There were no differences between the clinicians regarding sensitivity, specificity, diagnostic accuracy, number of cancers detected, number of melanomas found or biopsies indicated, however, there were significant differences between the four methods (Table 2). BLINCK had higher sensitivity and found significantly more melanomas than the other three methods. However, the Menzies method and clinical only approach had higher specificity and resulted in fewer biopsies than BLINCK. Diagnostic accuracy was the same for BLINCK, Menzies and clinical only, and all were better than the 3-Point checklist. BLINCK had higher sensitivity, diagnostic accuracy, number of cancers found and number of melanomas found than the 3-Point checklist, but had similar specificity and number of biopsies required.
Table 2. Mean values of sensitivity, specificity and diagnostic accuracy with 95% Confidence Intervals (CI) are shown, as well as numbers of melanomas and cancers found and biopsies required. Means followed by the same letter in each column were not significantly different.
The 50 lesions used in the trial were sourced from 46 patients, 22 male and 24 female, with ages varying between 30 and 60 years (average 58 years). Anatomical sites of lesions are shown in Table 3.
Table 3. Anatomical location of lesions
Four clinically benign lesions were included in the set without a histological diagnosis, (dermatofibroma, seborrhoeic keratosis, congenital naevus and monitored flat naevus), and the remainder were subjected to histological examination (Table 4).
Table 4. Breakdown of correct lesion diagnosis of the 50 cases.
Australia has the highest rate of melanoma in the world [6]. It is the third most common cancer in Australia in both men and in women [7]. Approximately two out of every three Australians will be diagnosed with skin cancer before the age of 70 [8] and roughly a million GP visits are made annually for skin cancer. This makes skin cancer the most expensive of all cancers for the Australian health system [9, 10]. More skin cancers are diagnosed and treated in Australia by primary care doctors than by medical specialists [11]. These generalists require a simple yet accurate screening tool that will allow the detection of melanoma and other skin cancers at an early stage when complete cure is possible. Currently, most introductory skin cancer courses in Australia endorse dermatoscopic evaluation of suspicious skin lesions as the preferred screening method, commonly using the 3-Point checklist or the Menzies method [12,13].
Other clinical features that may assist with the diagnosis of skin cancer have been previously studied. The "ugly duckling" sign has been shown to be of possible use in melanoma screening [4]. Importantly, the ability to assess whether a lesion is "different" from surrounding lesions does not appear to require advanced training. Hence, it would seem sensible that primary care clinicians seek out "ugly duckling" lesions when performing a skin examination, ("Lonely" in the BLINCK algorithm). Lesion change is also known to be associated with malignancy, particularly in patients over 50 years of age [14], and consideration of this clinical feature would also seem prudent. A disproportionate amount of concern for a lesion by the patient, ("Nervous"), may have significance for two reasons. Firstly, patients may be uncertain if their lesion has changed or perhaps they may simply fail to volunteer the history of change, bleeding, itch or soreness. They suspect that it is a cancer but assume the doctor is able to make the diagnosis by mere inspection without needing any clinical history. However, this history may be the only clue to malignancy in dermatoscopically bland lesions, and a false negative diagnosis may be made using dermatoscopic assessment alone. Secondly, dismissing a lesion about which the patient is quite concerned may have medico-legal consequences should it prove later to be malignant.
In this small trial, the BLINCK algorithm, which scored these extra clinical features along with basic dermatoscopic assessment, found more skin cancers and melanomas than the commonly endorsed methods in Australia. However, more excisions were required to achieve this result. This raises the question as to what is the best measure of "accuracy" in melanoma diagnosis. Argenziano has suggested that NNE, (number of melanocytic lesions needed to be excised in order to find one melanoma), may be useful for measuring accuracy in melanoma detection and compared the NNE in specialised and non-specialised clinical settings [15]. In his study the NNE reduced over time from 12.8 to 6.8 with specialised clinics but remained unchanged at 29.4 in non-specialised centres. This would seem to suggest that a level around 6.8 may be an appropriate goal for skin cancer clinicians. In our study, the overall NNE for melanoma by all clinicians using the BLINCK algorithm was 6, with the 3-Point checklist 11, the Menzies method 13 and clinical assessment only 22, suggesting that BLINCK may have value as a skin cancer screening tool.
As this trial was limited by the small number of skin cancers and melanomas, and by the fact that it was a virtual study without direct assessment of patients' lesions, it is difficult to draw definite conclusions regarding the benefits of combining clinical with dermatoscopic features in one diagnostic algorithm. Indeed, it could be said that clinicians using dermatoscopic-only algorithms implicitly incorporate relevant clinical aspects of the case in their decision making process. However, knowing how much weight to give these clinical aspects is often difficult for novices. Being forced to score the clinical with the dermatoscopic findings may help develop a more structured and holistic approach when deciding if a lesion requires biopsy.
1. Zalaudek I, Argenziano G, Soyer HP, et al., Three-point checklist of dermoscopy: an open internet study. Br J Dermatol. 2006;154(3):431-7.
2. Menzies SW, Ingvar C, Crotty KA, McCarthy WH. Frequency and morphologic characteristics of invasive melanomas lacking specific surface microscopic features. Arch Dermatol. 1996;132(10):1178-82.
3. Grob JJ, Bonerandi JJ, The 'ugly duckling' sign: identification of the common characteristics of nevi in an individual as a basis for melanoma screening. Arch Dermatol. 1998;134(1):103-4.
4. Scope A, Dusza SW, Halpern AC et al. The "Ugly Duckling" Sign: Agreement Between Observers. Arch Dermatol. 2008;144(1):58-64. CrossRef
5. Kittler H. Why the first step should be abandoned! Arch Dermatol. 2010;146(10):1182-3. CrossRef
6. Australian Institute of Health and Welfare and Australasian Association of Cancer Registries. Cancer in Australia 2001. AIHW cat. no. CAN 23. AIHW: Canberra, 2004.
7. Australian Institute of Health and Welfare (AIHW) and Australasian Association of Cancer Registries (AACR). Cancer in Australia: An Overview. Cancer series No 46. AIHW: Canberra, 2008.
8. Staples M, Elwwod M, Non-melanoma skin cancer in Australia: the 2002 national survey and trends since 1985. Med J Aust. 2006;184(1):6-10.
9. Australian Institute of Health and Welfare (AIHW). Non-melanoma Skin Cancer: General Practice Consultations, Hospitalisation and Mortality. Cancer Series no. 43 Catalogue no. 49. AIHW: Canberra, 2008.
10. Australian Institute of Health and Welfare (AIHW). Health System Expenditures on Cancer and Other Neoplasms in Australia, 2000-01. Health and Welfare Expenditure Series Number 22. AIHW: Canberra, 2005.
11. Askew DA and Wilkinson D. Skin cancer surgery in Australia 2001-2005:the changing role of the general practitioner. Med J Aust. . 2007;187(4):210-4.
12. SCCANZ. Certificate in Skin Cancer Medicine. SCCANZ web site, http://www.sccanz.com.au. Accessed October 30, 2011.
13. UQ. Certificate in Primary Care Skin Cancer Medicine. Skin Cancer Courses web site; http://www.skincancercourses.com.au/skc/index.htm. Accessed October 30, 2011.
14. Banky P, Kelly JW, English DR et al. Incidence of new and changed nevi and melanomas detected using baseline images and dermoscopy in patients at high risk for melanoma. Arch Dermatol. 2005;141(8):998-1006.
15. Argenziano G, Cerroni L, Zalaudek I, et al. Accuracy in melanoma detection: A 10- year survey. [published online ahead of print 2011 Oct 6]. J Am Acad Dermatol. 2011. http://dx.doi.org/10.1016/j.jaad.2011.07.019.


text:
Pyramido - Vatten LP
On Sale
From Halo Of Flies, US
"Pyramido are heavy and crushing. Vatten exemplifies these traits and the album is 38 minutes of emotively flattening guitars and distorted atmospherics.
Anguished screams tear out of the music as lonesome leads and tortured melodies rise out from the body of the music. Although the heaviness is a constant companion, it's not Pyramido's only weapon in the war against silence, as they also show they can play introspectively in more of a Post-Metal way.
On Vatten the band seem to have injected a little more nuance and shading into their songs; even though they had this on Saga for sure, it seems more developed here, with the time being taken to cultivate greater mood and feeling via the leads and rhythms.
Even when all of this happens though, the heavy riffs are not too far away, and the Sludge Metal gets its way in the end. The truly wonderful moments occur when the heavy riffs are providing the emotive content, and on those occasions Vatten is at its best.
These tracks compel you to pay attention, as the groovy and emotive guitars draw you in, engaging with their fury and hypnotic delivery.
Highly recommended." - Wonderbox Metal


text:
By ADAM LIPTAK
Published: May 24, 2011
WASHINGTON -- Conditions in California's overcrowded prisons are so bad that they violate the Eighth Amendment's ban on cruel and unusual punishment, the Supreme Courtruled on Monday, ordering the state to reduce its prison population by more than 30,000 inmates.
Justice Anthony M. Kennedy, writing for the majority in a 5-to-4 decision that broke along ideological lines, described a prison system that failed to deliver minimal care to prisoners with serious medical and mental health problems and produced ''needless suffering and death.''
Justices Antonin Scalia and Samuel A. Alito Jr. filed vigorous dissents. Justice Scalia called the order affirmed by the majority ''perhaps the most radical injunction issued by a court in our nation's history.'' Justice Alito said ''the majority is gambling with the safety of the people of California.''
The majority opinion included photographs of inmates crowded into open gymnasium-style rooms and what Justice Kennedy described as ''telephone-booth-sized cages without toilets'' used to house suicidal inmates. Suicide rates in the state's prisons, Justice Kennedy wrote, have been 80 percent higher than the average for inmates nationwide. A lower court in the case said it was ''an uncontested fact'' that ''an inmate in one of California's prisons needlessly dies every six or seven days due to constitutional deficiencies.''
Monday's ruling in the case, Brown v. Plata, No. 09-1233, affirmed an order by a special three-judge federal court requiring state officials to reduce the prison population to 110,000, which is 137.5 percent of the system's capacity. There have been more than 160,000 inmates in the system in recent years, and there are now more than 140,000.
Prison release orders are rare and hard to obtain, and even advocates for prisoners' rights said Monday's decision was unlikely to have a significant impact around the nation.
''California is an extreme case by any measure,'' said David C. Fathi, director of the American Civil Liberties Union's National Prison Project, which submitted a brief urging the justices to uphold the lower court's order. ''This case involves ongoing, undisputed and lethal constitutional violations. We're not going to see a lot of copycat litigation.''
State officials in California will have two years to comply with the order, and they may ask for more time. Justice Kennedy emphasized that the reduction in population need not be achieved solely by releasing prisoners early. Among the other possibilities, he said, are new construction, transfers out of state and using county facilities.
At the same time, Justice Kennedy, citing the lower court decision, said there was ''no realistic possibility that California would be able to build itself out of this crisis,'' in light of the state's financial problems.
The court's more liberal members -- Justices Ruth Bader Ginsburg, Stephen G. Breyer, Sonia Sotomayor and Elena Kagan -- joined Justice Kennedy's opinion.
The special court's decision, issued in 2009, addressed two consolidated class-action suits, one filed in 1990, the other in 2001. In 2006, Arnold Schwarzenegger, then governor, said conditions in the state's prisons amounted to a state of emergency.
The majority seemed persuaded that the passage of time required the courts to act.
Justice Scalia summarized his dissent, which was pungent and combative, from the bench. Oral dissents are rare; this was the second of the term. Justice Kennedy looked straight ahead as his colleague spoke, his face frozen in a grim expression.
The decision was the fourth 5-to-4 decision of the term so far. All four of them have found the court's more liberal members on one side and its more conservative members on the other, with Justice Kennedy's swing vote the conclusive one. In the first three cases, Justice Kennedy sided with the conservatives.
On Monday, he went the other way. This was in some ways unsurprising: in his opinions and in speeches, Justice Kennedy has long been critical of what he views as excessively long and harsh sentences.
''A prison that deprives prisoners of basic sustenance, including adequate medical care, is incompatible with the concept of human dignity and has no place in civilized society,'' Justice Kennedy wrote on Monday.
In his dissent, Justice Scalia wrote that the majority opinion was an example of the problem of courts' overstepping their constitutional authority and institutional expertise in issuing ''structural injunctions'' in ''institutional-reform litigation'' rather than addressing legal violations one by one.
He added that the prisoners receiving inadequate care were not necessarily the ones who would be released early.
''Most of them will not be prisoners with medical conditions or severe mental illness,'' Justice Scalia wrote, ''and many will undoubtedly be fine physical specimens who have developed intimidating muscles pumping iron in the prison gym.''
In his statement from the bench, Justice Scalia said that the prisoners to be released ''are just 46,000 happy-go-lucky felons fortunate enough to be selected.'' (The justices used varying numbers in describing the number of affected prisoners. California's prison population has been declining.)
Justice Kennedy concluded his majority opinion by saying that the lower court should be flexible in considering how to carry out its order.
Justice Scalia called this concluding part of the majority opinion ''a bizarre coda'' setting forth ''a deliberately ambiguous set of suggestions on how to modify the injunction.''
''Perhaps,'' he went on, ''the coda is nothing more than a ceremonial washing of the hands -- making it clear for all to see, that if the terrible things sure to happen as a consequence of this outrageous order do happen, they will be none of this court's responsibility. After all, did we not want, and indeed even suggest, something better?''
Justice Clarence Thomas joined Justice Scalia's dissent.
In a second dissent, Justice Alito, joined by Chief Justice John G. Roberts Jr., addressed what he said would be the inevitable impact of the majority decision on public safety in California.
He summarized the decision this way, adding italics for emphasis: ''The three-judge court ordered the premature release of approximately 46,000 criminals -- the equivalent of three Army divisions.''
Justice Alito acknowledged that ''particular prisoners received shockingly deficient medical care.'' But, he added, ''such anecdotal evidence cannot be given undue weight'' in light of the sheer size of California's prison system, which was at its height ''larger than that of many medium-sized cities'' like Bridgeport, Conn.; Eugene, Ore.; and Savannah, Ga.
''I fear that today's decision, like prior prisoner-release orders, will lead to a grim roster of victims,'' Justice Alito wrote. ''I hope that I am wrong. In a few years, we will see.''
PHOTOS: Overcrowding, long a problem, in a gym used as a dormitory at a prison in Chino, Calif., in 2007. (PHOTOGRAPH BY MONICA ALMEIDA/THE NEW YORK TIMES) (A1); Justice Antonin Scalia issued a rare oral dissent. (PHOTOGRAPH BY RICK GUY/THE CLARION-LEDGER, VIA A.P.) (A3)


text:
Tess Vigeland: Families trying to figure out just how much college is going to cost have some new tools. The U.S. Department of Education is out with a new website listing the cheapest and most expensive colleges in the country. Sitting Bull College in North Dakota gets the prize for lowest price at a public college.
The lists aren't just a public outing, though. Schools that have jacked up their prices the most in the last few years will have some explaining to do to the feds. From the Marketplace Education Desk at WYPR in Baltimore, Amy Scott looks behind some of the numbers.
Amy Scott: Some of the numbers are eye-popping. Consider Clayton State University in a suburb of Atlanta. Between 2007 and 2009, the public university's net price rose more than 1,500 percent. Net price is the average cost of attending minus grants and scholarships.
John Millsaps: One could make an assumption that someone is increasing costs through the stratosphere at that institution.
That's John Millsaps with the Georgia Board of Regents. He says that assumption wouldn't be quite right. During the years in question, Clayton State went from being a commuter school with no student housing to one with dorms. So it wasn't tuition, but dorms, that pushed the price up.
Millsaps: The important lesson I think with this is to simply look at the numbers and then start asking the questions of the institution to understand what the numbers mean and why.
Schools with big net price increases like Clayton State, or big tuition hikes like Arizona State, will have to explain those increases to the Department of Education. The idea is to give students and families more information -- and to shame colleges into lowering prices.
Lucie Lapovsky says it's probably not going to work. She's a higher education consultant and former president of Mercy College in New York. Lapovksy says the biggest increases are mostly at state schools.
Lucie Lapovsky: Which increased their tuition in large part as a reaction to significant reductions in state support. They don't have too many alternatives to maintain their revenue stream.
Another reason some schools jack up their prices is us. Tuition at private Jamestown College in central North Dakota jumped 39 percent, from $11,500 to $16,000 a year.
Polly Peterson is vice president for institutional advancement. She says the school raised its tuition to help pay for academic improvements, but also for appearances. Other colleges in the Midwest charge more.
Polly Peterson: And as we recruit students in that area, we do get that question. Parents will ask, "How can you offer the same quality if you're not charging the same prices?"
But again, the numbers don't tell the whole story. At the same time Jamestown raised tuition, it increased scholarships, so the actual cost of attending -- the net price -- went up a lot less.
Sara Goldrick-Rab teaches education policy at the University of Wisconsin-Madison. She says colleges get away with this because students and their parents let them.
Sara Goldrick-Rab: They're not walking away. And what I'm worried about is that, maybe students from low-income families will walk away. But the middle class and the upper class, they will continue to purchase it. And so the colleges and universities have very little incentive to do anything else.
Consumers armed with more information might start to fight back. The Department of Education's new website gives some of that information, if you're willing to do some digging.
I'm Amy Scott for Marketplace Money.


text:
We have requirement to manage notes database using TIM. The out-of-box notes adpater only manages the Notes Address Book. If we want to manage any custom notes DB, how we can do it by TIM? We want to add/modify/delete rows in custom notes DB.
Pinned topic TIM: How to manage Notes Database
Answered question This question has been answered.
Unanswered question This question has not been answered yet.
Updated on 2012-09-05T13:48:10Z at 2012-09-05T13:48:10Z by IdMNewOne
RuneHL 2000000YVH11 Posts
Re: TIM: How to manage Notes Database2012-08-28T13:55:02ZThis is the accepted answer. This is the accepted answer.I suggest that you build a custom adapter for that, using the adapter development toolkit will probably make it easier. The adapter runs in TDI and AFAIK there are standard connectors in TDi for Notes - otherwise you can use the java classes in Notes for the integration.
Note that it is usually a good idea to run the adapter on a separate machine (with the Notes client installed) as I have experienced that if more than one process uses the Notes API they can block each other and stall the adapter.
Re: TIM: How to manage Notes Database2012-09-03T07:58:30ZThis is the accepted answer. This is the accepted answer.
- RuneHL 2000000YVH
I was looking for some out-of-box solution using Lotus Notes connector in TIM, but it seems it is not possible, and we have to write custom adapter either using TDI connectors or java classes.
We tried connecting Lotus Domino through TDI using Local Client (installed on the same box) but it fails. Details are given below
Environment Details:
Tivoli directory integrator 7.0 8.5 32 bit
Lotus notes client 8.5 32 bit installed on same system.
Windows Server 2008 R2 64 bit
We have tried to establish connection using a lotus notes connector in TDI, but getting the below error:
14:40:41,031 INFO - LotusNotesConnector CTGDIS058I Connector com.ibm.di.connector.DominoConnector inherits from parent.
14:40:41,031 INFO - LotusNotesConnector CTGDIS187I Loaded com.ibm.di.connector.DominoConnector, 2.2-di7.0 %I%, 20%E%.
14:40:41,031 INFO - LotusNotesConnector CTGDIS064I Loading Attribute Map.
14:40:41,031 INFO - LotusNotesConnector CTGDIS065I Load Hooks.
14:40:41,031 INFO - LotusNotesConnector CTGDIS044I Initializing Connector.
14:40:41,031 INFO - LotusNotesConnector CTGDIS495I handleException , initialize, java.lang.reflect.InvocationTargetException
14:40:41,047 ERROR - LotusNotesConnector CTGDIS810E handleException - cannot handle exception , initialize
at sun.reflect.NativeMethodAccessorImpl.invoke0(Native Method)
at sun.reflect.NativeMethodAccessorImpl.invoke(NativeMethodAccessorImpl.java:79)
at sun.reflect.DelegatingMethodAccessorImpl.invoke(DelegatingMethodAccessorImpl.java:43)
at java.lang.reflect.Method.invoke(Method.java:618)
at com.ibm.di.connector.DominoConnector.initLocalThread(DominoConnector.java:1619)
at com.ibm.di.connector.DominoConnector.initialize(DominoConnector.java:507)
at com.ibm.di.server.AssemblyLineComponent.doInitialize(AssemblyLineComponent.java:1140)
at com.ibm.di.server.AssemblyLineComponent.initialize(AssemblyLineComponent.java:1115)
at com.ibm.di.server.AssemblyLine.initConnectors(AssemblyLine.java:1865)
at com.ibm.di.server.AssemblyLine.msInitConn(AssemblyLine.java:3346)
at com.ibm.di.server.AssemblyLine.executeMainStep(AssemblyLine.java:3168)
at com.ibm.di.server.AssemblyLine.executeMainLoop(AssemblyLine.java:2829)
at com.ibm.di.server.AssemblyLine.executeMainLoop(AssemblyLine.java:2812)
at com.ibm.di.server.AssemblyLine.executeAL(AssemblyLine.java:2781)
at com.ibm.di.server.AssemblyLine.run(AssemblyLine.java:1275)
Caused by: java.lang.UnsatisfiedLinkError: nlsxbe (.\nlsxbe.dll is not a valid Win32 application. )
at java.lang.ClassLoader.loadLibraryWithPath(ClassLoader.java:986)
at java.lang.ClassLoader.loadLibraryWithClassLoader(ClassLoader.java:950)
at java.lang.System.loadLibrary(System.java:453)
at lotus.domino.NotesThread.load(Unknown Source)
at lotus.domino.NotesThread.checkLoaded(Unknown Source)
at lotus.domino.NotesThread.sinitThread(Unknown Source)
We also registered the dll (nlsxbe.dll) & it got successfully registered but, still getting the same error.
Please let me know if you have any pointer on this.
Re: TIM: How to manage Notes Database2012-09-05T13:48:10ZThis is the accepted answer. This is the accepted answer.
- IdMNewOne 270004M8MK
Now my problem is that we have already TDI running on 64 bit JVM and used via TIM, we can just install new 32 bit TDI.
Is there any way so that 64 bit intstallation of TDI can use both 64 bit JVM and 32 bit JVM for different - different assembly lines.


text:
You can solve the twin problems of providing novel enrichment for ferrets and encouraging natural behavior — simply let your ferrets play outside. That's right, outside! After all, ferrets are domesticated polecats and polecats live in the wild, right?
Outdoor play areas must allow ferrets to play at will but still be contained and kept safe from outside dangers. Two basic strategies accomplish this: permanent and temporary.
Permanent outdoor enclosures include ferret runs, ferret-proofed gardens and fenced-off areas. These enclosures are generally excellent, but they have some of the same problems as indoor areas, namely that in the effort to make them ferret-proofed, they are often also made somewhat Spartan and boring. I have seen some outdoor enclosures that were essentially the equivalent of an empty swimming pool. Another problem is that the longer a ferret is in an enclosure, the greater the chance it can find a way out. Escapes can be of the type where a ferret finally figures the solution to get over the top, or digs a tunnel under the fence. A final problem with permanent enclosures is that some people cannot create one for any number of reasons, such as being renters or lacking an enclosable yard.
A temporary enclosure tackles the above problems, as well as addressing others, such as cost or portability. Most importantly, knocking together a temporary outdoor enclosure allows ferrets to experience the great outdoors almost anywhere, from your back yard to the local park. There are, of course, some disadvantages, but for the most part the enclosures work extremely well. Note that nearly everything mentioned about a temporary enclosure can be used to build or improve a permanent one as well.
Temporary enclosures are composed of: 1) a holding pen; 2) food and water dishes; 3) hiding and sleeping dens; 4) play equipment; and 5) shaders. It is also useful to include a small stool or chair so you can sit within the enclosure and play with the ferrets as they run wild. Temporary enclosures can be built from a number of materials, but if you want to use them outdoors and expect them to hold up to weather and ferret mistreatment, heavier materials work better. The same can be said of the other items; you need good quality to stand up to Mother Nature, so get the best you can afford.
Materials For A Ferret Holding Pen
The holding pen for playtime is the most important aspect of a temporary outdoor ferret enclosure. It needs to be high enough to prevent the escape of leaping ferrets but as short as possible to save weight and materials. For my ferrets, 32 inches is high enough, but I can't guarantee it will contain your ferrets. Use the height of your own ferret barriers as your guide.
I make the walls of the temporary enclosure out of 1⁄4 inch plywood, although Masonite, particleboard or other materials are acceptable. Cut a 4 by 8 foot sheet of plywood into three 4-foot by 32-inch sections (most lumberyards will cut it for you for a small fee or free).
Use as many sections as you like, but I find that more than nine gets out of hand. Usually, I only use four to six sections, but I have used as few as two (to form a triangle against a wall) and as many as 12. I usually paint the sections with a good outdoor paint to help resist weather, dirt and ferret feces.
While there are a lot of ways to connect the sections, I use cinderblocks and bungee cords. The advantage of using cinderblocks, besides them being extremely cheap, is that they are very heavy and ferrets cannot move them. They are more than capable of holding up the wood panels and are heavy enough to prevent "push-by" escapes.
Assembling The Ferret Enclosure
To build the temporary ferret enclosure, first decide how many panels you need (the more you use, the larger the enclosure), and then collect the other materials based on the number of panels you use. You need a wood two-by-four, two eye hooks and tent stakes, a bungee cord, and six cinderblocks per panel, so multiply those amounts by the number of panels desired. Before you construct the enclosure, screw the eyehooks in place on the top edge, about a foot from each end. You can paint the panels (and cinderblocks) if you wish.
The first thing to do is to use the 4-foot wood beams to frame the playpen. I place them on edge and pin them in place with two tent stakes, one at each end. Then I place the panels in position against the two-by-fours and stack three cinderblocks on the outside of each panel end to lock them in place. I hook a bungee cord through an eyehook, pass it through a cinderblock, and attach it to the opposite eyehook to hold the corners in place.
If put together properly, the staked wood beams hold the inner edge of the panel in position, the bungee cords hold the top corners tight, and the cinderblocks add stability and weight. The resulting enclosure is stable and fairly ferret-proof.
I do not use hinges nor attach the panels to each other in a permanent or fixed manner. This is because attached panels require level ground, otherwise gaps and holes are created that entice a ferret to escape. Short, individual panels naturally overlap each other and "self-level," allowing the bottom edge to seat better on the ground. The two-by-fours also help hide gaps and work marvelously for holding the panels in place.
Inside The Ferret Holding Pen
Regardless of the amount of time a ferret spends in an outdoor enclosure, it is critical that a source of water be provided. I provide at least two water dishes and at least one water bottle per holding pen.
Unless your ferrets are going to spend a long time outside, the need for food is minimal. A single small dish of food is enough, but toss out the food at the end of the day to prevent possible contamination to indoor food.
I always add enough nest boxes so there is more than enough room if all the ferrets want to sleep. Be careful that your ferrets cannot push the boxes to the edge of the holding pen, allowing them to escape. Pin the boxes in place with tent stakes if necessary.
To increase interest, I usually hide a number of food treats in the enclosure before tossing in the ferrets. They now expect small food treats, so as soon as they hit the ground, they are off looking for snacks. This usually degenerates into a wrestling free-for-all and extended play.
The final thing to think about is shade. Direct sunlight can rapidly overheat your ferrets. Even if they take refuge in a nest box, direct sunlight can turn their bedrooms into tiny ovens.
Create shade by sticking a few umbrellas into the ground, covering one end of the enclosure with a tarp, or just making sure there are a number of shade plants inside the pen. For hot days, limit outdoor time to early morning, or add a cooling mister to lower the temperature of the interior of the cage.


text:
"The Lucky Ones" is as close as a movie about three Iraq war soldiers should come to mediocre TV comedy.
Tim Robbins, Michael Peña, and Rachel McAdams play Fred Cheaver, TK Poole, and Colee Dunn - a reservist, a medic, and a private, battle-wounded strangers with a common Army bond. Fred has finished his last tour, and TK and Colee are on a monthlong leave.
They arrive at JFK airport together, discover that a blackout has canceled their connecting flights, and manage to snag the last rental car, which they drive to St. Louis where Cheaver lives. A series of glitches and catastrophes follow (divorce papers, a car accident, $20,000 to raise, a tornado, impotence), some more bearable and believable than others.
Director Neil Burger co-wrote the movie with Dirk Wittenborn, and while he doesn't always seem sure whether to play the material for pathos or comedy, he's confident with his cast.
Robbins keeps a tight lid on what could have been another of his yahoos. He takes a put-upon a man and relieves him of any gratuitous angst. Cheaver loses it. He breaks down. But Robbins never cracks up; he's too busy playing the adult to two kids. It's one of his smartest performances.
Peña is as good as usually he is - funny, slow to anger, touching. He and McAdams have a sensual scene together huddled inside a drainpipe. She's almost unrecognizable, with her hair pulled back and a mouth that never stops running. The character is a sweet, twanging mess of silliness, churlishness, and childishness. This is a Hilary Swank part that Swank herself probably couldn't relax enough to play.
Occasionally, you wonder how these three characters might handle the theater of combat. "The Lucky Ones" doesn't have a thunderous statement to make about the war or any flashback footage to share. It contains very little military shop talk. It's the emotional opposite of Kimberly Peirce's rumbling "Stop-Loss," which came out in the spring and also featured a soldier on a forced road trip.
But "The Lucky Ones" has more chilling real-world details. When we see a recruiting booth stationed outside a casino, we know the Army is another gamble. But the woman and two men in this movie need the military as much as the military needs them. "The Lucky Ones" is part of a disturbing new era in American war movies. Military service is no longer simply an expression of patriotism. It's another way to make ends meet.
Wesley Morris can be reached at firstname.lastname@example.com.


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Ryan Villopoto wearing Oakley's all-new Airbrake MX goggle at the start of the 2013 Supercross season.
Whether you're launching off the face of a jump or trailing into inside rut, in motocross, vision is everything. Oakley, a leader in the world of optics aims to push the envelope of what we as riders come to expect with its latest Airbrake MX Goggle. Oakley's latest eyewear features innovative design features that not only improve performance but safety, too.
"We've take the culmination of every break-through that we've developed over three decades of refinement, fit and comfort," says former Supercross champ and Oakley front man Mike Bell. "It's so vastly different from the status quo out there; the difference will be night and day."
To accomplish this Oakley tapped some of its brightest minds within its ultra-secretive engineering department with one goal in mind: perfection.
"It is a game changer and when you go to the starting gate, it's going to help," says two-time Supercross champ James Stewart.
"I'm really excited about this goggle. It revolutionizes the goggle world," adds legendary Supercross and motocross champ, Ricky Carmichael. "When you think of Oakley this is what you associate them with. The biggest thing that blew my mind was the peripheral vision and how clear it was when you were looking through it."
Oakley's Supercross and motocross factory pilots speak before an audience at Oakley's HQ in Foothill Ranch, California.
The Airbrake uses a modular design in which each component can be replaced when necessary. The frame of the Airbrake consists of Oakley's proprietary O Matter synthetic plastic. It is designed to be both lightweight while offering the optimum blend of flex and stiffness. A lever-type mechanism on each side, dubbed by Oakley as Switchlock, allows the rider to easily switch lens based on preference or outside light. Another key feature is that the frame holds the lens in such a way that it doesn't apply any pressure on the lens for enhanced clarity.
"Switchlock allows the lens to be changed super-fast," says Bell. "So a rider can adapt to what Mother Nature throws at them. You have all of our performance lens tints available. Whether you're going through a day session out on the track doing practice laps, to the night time main event you can pop in the perfect lens to suit those conditions."
Perhaps the biggest attribute of the new goggle is its lens. For the first-time ever Oakley is using its proprietary Plutonite material – similar to what's used in its sunglasses. Not only does it provide superior impact resistance from dirt and rocks it features an extremely wide viewing angle which enhances the rider's peripheral vision.
The Airbrake features a modular design in which each component can be removed and replaced if necessary.
"A typical MX lens is stamped from a flat sheet of generic material and literally bent to fit inside that goggle frame. That sort of warping causes visual distortion," Bell explains. "We injection mold the lens under extreme pressure to obtain precise optical geometry."
In addition to tear-off posts the goggle can be outfitted with a new roll-off system in which canisters are attached inside the strap. The roll-off is activated by pulling on a left-hand-side strap thereby exposing an fresh film, strip which allow you to see during treacherous riding conditions.
"The roll-off system is huge for every rider that rides in the mud," says reigning Supercross champ Ryan Villopoto. "It may be a little more expensive looking at it but what you get when you buy that goggle; you can have one goggle with a tear-off set-up, and can go straight to the roll-off system with the same goggle. It's so universal."
Geico Honda's Eli Tomac has already recorded the Airbrake's first win racing win at the inaugural Anaheim Supercross round a few weeks ago. The standard Airbrake MX goggle will be available beginning March 15, 2013, at a cost of $160. The Race-Ready, roll-off edition will be priced at $200 and available May 1.


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It was six months ago that I first started raving about (500) Days of Summer, and with the year half over it's still my favorite film of the year. Soon you'll be able to tell me to shut up and form your own opinions, since it finally slips into theaters in limited release on July 17th.
(500 Days of Summer) is the story of boy meets girl. Tom, the boy, still believes, even in this cynical modern world, in the notion of a transforming, cosmically destined, lightning-strikes-once kind of love. Summer, the girl, doesn't. Not at all. But that doesn't stop Tom from going after her, again and again, like a modern Don Quixote, with all his might and courage. Suddenly, Tom is in love not just with a lovely, witty, intelligent woman – not that he minds any of that -- but with the very idea of Summer, the very idea of a love that still has the power to shock the heart and stop the world.
Below we have seven clips from the film and Fox Searchlight has actually done something worthwhile here. The clips contain moments from some of the best scenes in the movie, but to avoid spoiling them they've removed certain key moments or omitted the movie's gorgeous, mood setting soundtrack. The net effect here is that even if you watch the clips to get a feel for the film, once you see them in context they'll still feel brand new.
Watch all seven clips below and walk away spoiler free.
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Africa Cup of Nations 2013: Day 13 Scores and Results SummaryFebruary 2, 2013
On Saturday, it was win or go home in the quarterfinal stage of the Africa Cup of Nations. Well, except for South Africa, which is already at home as the tournament's host.
In the first game, Ghana were set to face Cape Verde. In the afternoon game, South Africa had Mali to deal with, the team that finished third in last year's tournament.
These are for are the marbles, folks. Let's recap Saturdays action at the Afcon.
Ghana Defeats Cape Verde, 2-0
Brace yourselves for this—Mubarak Wakaso was a super sub for Ghana on Saturday, coming off the bench and scoring both goals to send Ghana to the semifinals.
But don't be fooled by that score. Cape Verde came to play in this one, and Ghanas's keeper Gatau Dauda, not Wakaso, was the man of the match.
The first half was a rather cagey, cautious affair, and neither team seemed keen to leave themselves vulnerable in the back. The first 45 minutes certainly weren't the most exciting football we've seen at the tournament. Ghana did control the ball, however, maintaining 68-percent possession.
The second half would open up a bit.
Wakaso was subbed on just a minute into the second half, and he would make his presence felt quickly. After Asamoah Gyan was fouled in the box—though that call will be justifiably scrutinized as it looked like a weak challenge and not worth calling a penalty—Wakaso calmly handled the penalty kick and put Ghana ahead.
Cape Verde would ratchet up the pressure after that, but the team simply couldn't find that final touch to earn the equalizer. Truly, Cape Verde were a bit unlucky to lose this one, and Dauda was brilliant in net for Ghana.
Ghana would earn its second goal in stoppage time, as Cape Verde keeper Vozinha came forward for a corner kick in a desperate attempt to tie the game. Ghana would win the ball back, and Wakaso would break away from the pack and easily slot home his second goal of the day.
Ghana will face the winner of Burkina Faso and Togo.
Mali Defeats South Africa, 1-1 (3-1 on Penalties)
It took penalties to decide it, but Mali will move on to the semifinals after defeating South Africa 1-1 (3-1 on penalties). For the hosts, the tournament ends in bitter disappointment. And for the second tournament in a row, Mali has knocked off the host country (Gabon in 2012).
South Africa was the better team early, keeping the pressure high, dominating possession and notching the first goal of the game after Thuso Phala found a streaking Tokelo Rantie, who calmly deposited the ball into an empty net.
But South Africa slowly let Mali back into the game, and Mali made them pay. Seydou Keita—who else?—would head home the equalizing goal in the 58th minute off a Mahamadou Samassa cross.
And then the stalemate begin, as the rest of the second half and both overtime sessions would go scoreless, leading to the ever-controversial penalty shootout.
Siphiwe Tshabalala would get South Africa off to a solid start, scoring to start off the shootout. But things would go downhill from there for the hosts.
While Cheick Diabate, Adama Tamboura and Mahamane Traore would all execute for Mali, Dean Furman, May Mahlangu and Lehlohonolo Majoro would all fail to find the back of the net. And with that, Mali moves on and will face the winner of Ivory Coast and Nigeria.


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Bangalore, Feb 12: A local court today extended the CoD custody of terror suspect Mohammed Asif and posted hearing of his bail application to later in the day. Asif was produced in the house of the Judicial Municipal First Class Judge amidst tight security, due to the tense situation that prevailed in the wake of lawyers opposing the grant of bail to him and against advocates, who moved his bail application.
Elaborate bandobust was made in the court, where Asif's bail application would come up for hearing in the afternoon. Yesterday, lawyers had boycotted court proceedings and took out a protest march against fellow-lawyer Mohammadannavar, who had moved Asif's bail application. The Ram Sena workers, who were up in arms against Mohammadannavar for moving Asif's bail application, staged a protest and tried to prevent him from entering the court.


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TORONTO, March 31 (Reuters) - About 300 employees of Ford Motor Co are set to return to work in Windsor, Ontario, after the company announced on Monday it would reopen an engine plant shuttered in November. The announcement comes on the back of a deal between Ford and the government of Ontario province, which will chip in C$17 million ($16.6 million) toward Ford's C$170 million investment in a new engine program. Ford didn't say what kind of engine would be produced or when production ...
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Hayden Moore, quarterback from Clay-Chalkville High School in Ala., received an offer from Cincinnati this week. He jumped on the opportunity and committed to the Bearcats. It was something he wa...
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Els Pyreneus Rivesaltes Ambre NV (Cotes du Roussillon, France)
A blend of Grenache Noir and Grenache Gris from winemaking legend, Jean Marc Lafage.Read More
Seasonal Eating and Drinking
Wine matches for seasonal produce for WinterRead More
What to drink with your eggs this Easter
How do you like your eggs in the morning? With a shot of hazelnut liqueur, perhaps? We will soon all be tucking into a feast of chocolate egg goodness and it can sometimes be tricky to decide what to pair with all the sweetness. So we've done the hard work for you…Read More
Hidden gems of Spain: beyond Rioja
While everyone loves the oaky, comforting embrace of a good Rioja, there's a whole lot of other Spanish wines that deserve attention.Read More
Swinney: Australian wine like no other
It all started with a few vines. Matt Swinney saw an opportunity where his ancestors simply saw farmland. Frankland River, where he planted his vines, is one of the most remote agricultural areas in Western Australia.Read More
5 reasons why rosé loves food
Rosé is too often dismissed as just a bit of fun. But there's a whole lot of serious pink wine out there that deserves your attention. From pale salmon to nearly-red we take a look at the full spectrum of pinks and what to eat with them.
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A guide to the 2015 vintage: Spain
On the whole 2015 was a good year for Spain. The summer heat was offset by September rains, which lead to incredibly well-developed fruit. It was a year for both white and red grapes to perform, despite the early heat.Read More
Tomas Cusine – a Catalan maverick
Tomas Cusine worked for many years at his family's iconic estate Castell del Remei – however, in 2003 he decided to forge his own way, setting up his very own eponymous winery in Spain's Costers del Segre.Read More
4 Reasons Why You Should List Sangria this Summer
Summer specials, made on the premises, are a great plus for any bar. Think about Sangria and use the (hopefully) good weather to your advantage to build a buzz this summer.
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A guide to the 2016 harvest in the Northern HemisphereA guide to the 2016 harvest in the Northern Hemisphere Read More
Judging a book by its cover: Beautiful label designWhy a great wine label can generate even greater sales. Read More
Extreme winemakingThere's winemaking the easy way: in a temperate climate, on nice flat ground with lots of machinery and chemicals to help. And then there's the hard way… Read More
Friday Quiz: Extreme winemakingThere's winemaking the easy way: in a temperate climate, on nice flat ground with lots of machinery and chemicals to help. And then there's the hard way… Read More
Our favourite wines for autumnThe mornings (and evenings) are darker, the trees are bare and pavements full of leaves. There's one month of autumn left before we head into the joy (and craziness) of the festive season, so we round up four of our favourite autumnal wines – from New World Pinot to classic Barbera. Read More
Bodegas Tomas Cusine Vilosell (Costers del Segre, Spain)
Read all about the fantastic Vilosell from Bodeags Tomas Cusine.Read More
Tabula – Boutique Winemaking in the Ribera del Duero
Tabula really is testament to what Ribera del Duero is all about.Read More
Sherry, Food and the Trade
The trade loves Sherry but the customer still feels disconnected.Read More
Sauvignon Blanc - The Future of Rueda?
Rueda producers are beginning to discover the area's ability to produce excellent Sauvignon Blanc.Read More
Understanding Sherry
The Bibendum guide to all things Sherry, one of the world's greatest wine styles.Read More
Sangria #1
Time for sunshine, and time for summery cocktails. Try one of our recipes from Bibendum's Taste of Summer range.Read More


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Bishop Billal Parrish, of Egg Harbor Township, has spent almost 40 years serving the independent Shiloh Temple Apostolic Cathedral of Atlantic City.
The Pentecostal minister has been pastor since 2004, and before that he supervised Sunday School and was assistant pastor.
Earlier this month, church members and church Mother Ethel Waiters presented Parrish for ordination as bishop in a ceremony led by Parrish's boyhood friend Bishop Curtis Bordley, of Dover, Del.
Parrish and Bordley have come a long way since meeting at age 12 while growing up in Egg Harbor Township. They both fell away from attending church at about age 18, said Parrish, 67.
In his late 20s, after a decade of living outside his religion, Parrish found his way back, along with the woman who would be his wife, Mary Waiters. Both began attending Shiloh Temple, where Waiters' father, Bishop James A. Waiters, was founder and pastor.
Soon after, Parrish and Bordley met again.
"I saw him walking by the side of the road, picked him up and asked where he was going. He said he's looking for a church and to be saved," Parrish said. So he invited Bordley to Shiloh, where he was baptized. Later, Bordley went into the ministry.
"I felt if anyone would be the chief consecrator, it would be him," Parrish said.
Shiloh will hold a Praise in the Park gospel music event, led by Assistant Pastor Willie Jenkins, from 2 to 6 p.m. Aug. 25 at McClinton Park, New Hampshire and Melrose avenues in Atlantic City. School supplies will be given to students.
E! alum at Atlantic Cape
Atlantic Cape Community College communication professor Keith Forrest, of Collingswood, worked at the E! Entertainment Television network in its infancy, and recently attended the network's 20th anniversary reunion in Los Angeles, a spokesperson for Atlantic Cape said.
Forrest, co-creator of Atlantic Cape's communication degree program, worked on the talk show "The Inside Word," and served as a writer and producer for "E! News Daily" until February 1995, the college said.
Musical to benefit heart-care fund
The Gabriel Project, a Vineland charity founded by former teacher Mark Melamed to provide travel funds for children in need of heart care, is looking for performers for a fundraising production of "Happy Days: The Musical."
Auditions for ages 14 and older will be held at 6:30 p.m. Monday and Tuesday at Veterans Memorial School, 424 S. Main Road in Vineland. Performances will be held Nov. 15-17, Public Relations Director Rachel Pinkstone-Marx said.
Everyone Has a Story appears Sundays, Mondays and Wednesdays.
Contact Michelle Brunetti Post:


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Based in Englewood Cliffs, NJ, ConnectOne Bancorp (NASDAQ:CNOB) scheduled a $44 million IPO with a market capitalization of $131 million at a price range mid-point of $27.50, for Tuesday, February 12, 2013.
Five IPOs are scheduled for the week of February 4. The full IPO calendar is available here.
S-1 filed February 1, 2013.
Manager, Joint Managers: Stifel. Co Managers: Keefe, Bruyette & Woods; Sandler O'Neill.
CNOB is a small New Jersey bank that generated a 25% increase in net interest income for the nine months ended September 2012 vs 2011, along with a 27% increase in net profit.
The IPO will increase stock holders equity by $40 million, to $110 million from $70 million. IPO money will be used to expand the business.
|Valuation Ratios
IPO Mrkt
Price /
Price /
Price /
Price /
% offered
|annualized Sept 9 mos
Cap (MM)
|Interest income
in IPO
|ConnectOne Bancorp (CNOB)
Compared to four other New Jersey banks CNOB is priced in the middle in terms of Price / Sales (Interest Income), Price / Book and Profit Margin. CNOB is the most expensive in terms of Price / Earnings. The four New Jersey banks are Penns Woods Bancorp (NASDAQ:PWOD), Peapack-Gladstone Financial (NASDAQ:PGC), Center Bancorp (NASDAQ:CNBC), and Lakeland Bancorp (LBAI).
CNOB is growing faster than most New Jersey banks but the P/E is also higher. The expectation is that the IPO money will fuel a profit surge.
Because CNOB is on the small side in terms of assets, it may be easier to generate organic growth with the new capital. But, because the IPO is relatively small the after-market trading may be somewhat illiquid.
Ok to take: neutral to positive.
CNOB was formed in 2008 to serve as the holding company for North Jersey Community Bank.
CNOB is a community-based, full-service commercial bank that serves the banking needs of small to medium-sized businesses, professional entities and individuals than can a branch or subsidiary of a larger out-of-market institution.
CNOB was recognized as one of the top five performing community banks in 2010 and one of the top 15 best performing community banks in 2011 with assets between $500 million and $5 billion in the United States by SNL Financial LC.
CNOB's banking offices are located in Bergen, Hudson and Monmouth Counties in New Jersey, which include some of the most affluent markets in the United States.
CNOB also attracts business and customers from a broader region, primarily defined as the northeastern quarter of the State of New Jersey, from Route 195 to the south and Route 287 to the west to the New York state border on the north.
Bergen County, where 93.5% of CNOB's total deposits as of September 30, 2012, are located, is home to significant employers including Benjamin Moore, the Hertz Corporation, Pathmark and Volkswagen Group of America. Furthermore, CNBC, LG USA and Unilever of North America are headquartered in the Borough of Englewood Cliffs (company headquarters location).
Looking at the broader state economic environment, 20 Fortune 500 companies are headquartered in New Jersey, primarily concentrated in the northeast quarter of the state, the core market area. Among Russell 3000 companies, 102 are headquartered in New Jersey, and Bergen County is home to more of these companies (17) than any other county in the State.
Historically, CNOB has concentrated on organic growth, through opening new branches and offering new technology and product delivery channels to acquire new customers.
CNOB expects the bulk of its growth to continue to be organic. The goal is to open new offices in the counties contained in the broader trade area discussed above.
However, CNOB does not believe that it needs to establish a physical location in each market that it served.
CNOB believes that advances in technology have created new delivery channels which allow CNOB to service customers and maintain business relationships without a physical presence, and that these customers can also be serviced through a regional office.
CNOB believes the key to customer acquisition and retention is establishing quality teams of lenders and business relationship officers who will frequently go to the customer, rather than having the customer come into the branch.
CNOB's expansion into Monmouth County, through the opening of the Holmdel, New Jersey, office, is an example of this strategy. CNOB opened the branch in July 2011 and, as of September 30, 2012, had $20.0 million in total deposits at the Holmdel branch.
While CNOB waived overdraft and certain other fees for customers in the immediate aftermath of the storm, the costs incurred by the Bank were not significant, and the storm did not have a significant impact on CNOBs operations.
New Jersey Banks
Penns Woods Bancorp
Peapack-Gladstone Financial
Center Bancorp
Lakeland Bancorp
Larger Regional Banks
Valley National Bancorp, (NYSE:VLY)
Susquehanna Bancshares (NASDAQ:SUSQ)
No dividends.
CNOB expects to net $40 million from its IPO. Proceeds are allocated to provide regulatory capital to support future asset growth and continued expansion of the Bank's business.
Disclaimer: This IPO report is based on a reading and analysis of CNOB's S-1 filing, which can be found here, and a separate, independent analysis by IPOdesktop.com. There are no unattributed direct quotes in this article.
Disclosure: I have no positions in any stocks mentioned, and no plans to initiate any positions within the next 72 hours. I wrote this article myself, and it expresses my own opinions. I am not receiving compensation for it. I have no business relationship with any company whose stock is mentioned in this article.


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Web Junk: Peter Pan Proposal
JAKE AND THE NEVER LAND PIRATES - "Never Land Rescue" - When Never Land begins to disappear, Jake must go on his most heroic mission ever to save the magical Forever Tree, the source of magic throughout all of Never Land. Guiding Jake on his quest is Tinker Bell, who makes her first-ever appearance in the series. This episode of "Jake and the Never Land Pirates" airs Sunday, September 29 (6:00 PM - 6:55 PM ET/PT), on Disney Junior. (Disney Junior via Getty Images) JAKE, TINKER BELL, PETER PAN(Disney Junior via Getty Images)


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One doesn't exactly think "clandestine†when mixing sangria but that's exactly what it is to make the drink in Virginia. It has been illegal to make the popular Spanish mixed drink there since shortly after the repeal of national prohibition. And not just sangria. The law says that combining wine or beer and spirits and pre-mixing or storing drinks outside their original containers, except for those in approved frozen-drink dispensers is prohibited. Violating that law can actually send a bartender to jail for a year!
But things may be changing. According to this piece that originated in the Washington Post, the General Assembly will be considering an exception to the law for sangria. That's right, rather that just repeal an obviously stupid law they are going to allow a sangria exception! I am continually amazed by the ridiculous patchwork of liquor laws in this country.liquor law sangria Virginia


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Ugh. I saw them with Sky Eats Airplane. Great live, horrible album methinks. And The Word Alive stole the show.
My God I hate this band... also, lol, my old band opened for these guys and All Time Low. We played brutal death metal, some jackass decided to book that tour on the same day as A Different Breed Of Killer lol.
Album Rating: 3.0Shit. I can only imagine the horrified look on fans' faces.
Digging: Adimiron - Et Liber Eris
Album Rating: 2.5Awesome. I love a tour with mismatching bands. Like Sounds Of The Undergroun 2005 or 2006 which pitted The Devil Wears prada with Behemoth.
Digging: Vreid - I Krig
The Devil Wears Prada didn't play SOTU 2006.
this is a really shitty album
Album Rating: 3.0I didn't think it was too bad...
Album Rating: 2.5well to be honest I didn't really like this album, it has a couple good songs but thats it. After Reach I was so hooked on ESTK and expected something great of this album but it kinda let me down, stick with thier album reach and let this slide by.
Album Rating: 1.5This is the most contrived and terrible POS I've listened to in a long time... just horrendous. The vocals in particular.
Album Rating: 3.0Dropped my rating. This hasn't had a lot of longevity and the new one destroys this.
Album Rating: 3.0Brandon never sucked at singing it was just a different tone.
Their song Darling is arguably their best song. Atleast it's mine.
Album Rating: 3.5I enjoy Brandon Anderson on this album, I think the screaming really shows off how well the songs are written. While you might not want the screaming to be sub-par, I do love this album because of his "vocal style"
Album Rating: 3.5Brandon's vox aren't as good as Reach, but still a solid album.
this review is cited to justify the screamo tag on their wikipedia page
Digging: 21 Savage, Offset and Metro Boomin - Without Warning
Album Rating: 3.5Of all the things to pick.
Bands: A B C D E F G H I J K L M N O P Q R S T U V W X Y Z


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A few weeks ago, Walmart Stores, Inc. presented its growth plans for the fiscal year ending January 31, 2010 at its annual conference for the investment community. The company plans to add about 38 million square feet globally compared to the 44 million square feet it added the prior year. Walmart plans to increase global square footage by about 37 million square feet in fiscal year 2011. Future stores will be eight percent smaller, and cost 16 percent less to build.
In the U.S., Walmart will "continue to focus on further improving the returns of its supercenter format" through remodeling existing stores and accelerating the growth of new stores. This year, Walmart expects to add 15 new Sam's Club stores, and between five and ten new Sam's Club stores in fiscal year 2011.
Walmart International plans "aggressive investment… in growth markets such as China and Brazil." The world's largest retailer expects to add about 23 million square feet in fiscal year 2010 in its international stores, and about 25 million square feet in fiscal year 2011. Acquisitions are not included.
"Our plan for growth is clearly intended to increase shareholder value," said Tom Schoewe, executive vice president and chief financial officer. "In the U.S., we're building new stores and accelerating the pace of our remodels because they have been so successful at winning and retaining customers."
"We're stepping up growth in our International operations to take advantage of growing economies and opportunities in emerging markets, such as China and Brazil," Schoewe said.
Walmart's Project Impact initiative
Walmart U.S. will complete Project Impact remodels this month at more than 30 percent of its 3,538 stores. By the end of fiscal year 2012, about 70 percent of Walmart U.S. stores are expected to be updated through Project Impact. A September issue of Time magazine called Project Impact a "massive store and strategy remodeling effort."
According to the Time article, Project Impact has three goals:
- Cleaner, less cluttered stores
- Friendlier customer service
- Hone in on categories where the competition can be killed
"They've got Kmart ready to take a standing eight-count next year," said retail consultant Burt Flickinger III, managing director for Strategic Resources Group. "Same with Rite Aid. They've knocked out four of the top five toy retailers, and are now going after the last one standing, Toys R Us. Project Impact will be the catalyst to wipe out a second round of national and regional retailers."
Supermarkets will also be impacted by Project Impact. "It's the second twist of the knife. For most supermarkets, the first twist was all the supercenters getting built, but now there's just that much more competition from them," said David S. Rogers, president of DSR Marketing Systems.