text:
Choose Your Blade Lock
And You're Ready To Roll.
Folding knives have been around since the days of Celts and Romans, but they weren't always the choice for hard use. If you ever had a traditional slip-joint blade inadvertently jump the spring and take a bite out of your knuckle, chances are you already know why.
Sometime around the early- to mid-1800's, when folding knives were beginning to achieve a high degree of sophistication, the tinkering with locking mechanisms began to take root. Some folding dirks from the era were fitted with a tabbed lock on the spine, which would be the precursor to the lock-back we know today. Later, in the early 1900's, the original locking liner was invented and, for the most part, used on the screwdriver function of multi-blade electrician knives. But it would be half a century later until a locking knife came along to capture the hearts and minds of cutlery lovers. That knife was the Buck 110.
The Buck 110 lockback was the first locking folder to be widely accepted by
the buying public. Shown here is the original in brass and wood handles,
and the more modern version in green paper composite grips.
Cold Steel is one of several top manufacturers who still pay unabashed homage to the lockback.
Shown here is their exotic Talwar model with the lock detent located mid-handle.
The liner lock and frame lock are the same conceptually, but differ in basic design.
From Spyderco comes the Perrin PPT liner lock (top) and the Southard frame lock (bottom).
Lockback Evolution
The lockback is the natural evolution of the ubiquitous slip-joint folder, which uses a rocker arm on the backside pushing against a torsion spring in the liners. This arm pivots and has a tab on the topside, which fits inside a corresponding shaped notch located on the tang, or base of the blade just below the pivot. Once the two interlock, the blade can only be unlocked by pushing the rocker arm into a detent in the handle, which in turn compresses the spring. This forces the tab out of its locked position in the tang, allowing the blade to be folded. One of the key benefits of the lock-back is you can actually see the blade release. This is a key advantage over the liner lock (see next mechanism) which has the release hidden in the handle.
The Buck 110, now celebrating its 50th year, was the first widely accepted locking folder because it was sturdily built and easy to operate. The knife was enthusiastically embraced by hunters, the first folding knife to achieve such an honor, and Buck still produces the knife at a clip of approximately a million units per year. The lockback's endurance as a viable design can be witnessed by the fact other highly reputable cutlery companies such as Spyderco and Cold Steel continue to use the mechanism on their modern designs. The 110 also holds the reputation as being the most copied knife design in history. I did a cursory survey of imitations of the folder several years back and counted 36 companies who offered imitations of the folder so close in styling they could only be considered knock-offs! A variation of the lockback has the spring release detent located halfway up the rear spine and is alternately referred to as a midlock.
Like the lockback, the original liner lock was borne out of the slip joint folder. The concept is simple. A liner "leaf" inside the frame is bent at an angle designed to cant inward once the blade is fully engaged. This causes the leaf to block the tang, keeping the blade locked against the rear stop. To disengage the blade the leaf is bent back against the frame wall, allowing the tang to fold inward.
Back in the early 1980's a brilliant custom knifemaker by the name of Michael Walker took the locking liner idea and thoroughly modernized it. His design is the most widely used lock on folders today. He did away with the external release tab and hid it within the frame, ditched the backspring and replaced it with a blade stop, and added an internal ball bearing detent on the blade tang to keep the blade closed inside the handle.
Walker's liner lock largely went unnoticed until the early 1990's when the first Gulf War hit. This was the dawn of the modern day tactical folder, and the custom knifemakers who got in on the ground floor embraced the liner lock as the lock du jour. Today, over 20 years later, the tactical folder is still the hottest segment of the cutlery market and the overwhelming majority are of liner lock design.
The liner lock mechanism has several advantages. Although it requires precision, it is a relatively simple design and hard to defeat. Because the lock is hidden there are no external parts to snag the pocket or sheath when being accessed. And when used with a pocket clip the liner lock makes for an excellent semi-concealed, easy-to-access carry.
In the mid-1980s' some custom knifemakers began to take note of Walker's liner lock. One such artisan was South African Chris Reeve. A master machinist by trade, Reeve had been making knives on the side. In 1987, a client sent him a Walker liner lock, requesting he make one for him. Reeve didn't like the thinness of the liner lock design so he acquired some 3/16-inch titanium and made a prototype of what is now the modern day frame lock. This design has the locking leaf machined out of the back frame, resulting in a much beefier mechanism. Reeve named his knife the Sebenza, the Zulu word for "work." In 1989 the knifemaker moved his family to Boise, Idaho, and within a short few years his Sebenza was one of the hottest knives on the market.
Today the frame lock, or "Integral Lock" as Reeve prefers to call it, is arguably considered the strongest locking mechanism available. One key reason the Sebenza caught on so quickly is it's built like a tank. Once a bevy of noted custom knifemakers jumped on board with the mechanism, it became elite and before long the factory manufacturers joined the party. Frame locks are not as common as liner locks because they are more difficult to make. Typically the rear frame is made of titanium, which also adds to the cost, but slimmer versions have been produced using stainless steel. A host of other materials can be found on the front frame, including G-10 composite and carbon fiber. Reeve offers his Sebenza in large and small models and, though he's added a host of other models to his line, the knife is still his hottest seller. Serious users and collectors alike line up for them as fast as Reeve can make them.
The frame lock can be used in a wide variety of design styles. At top is Chris Reeve's
original Sebenza; at bottom CRKT's Ken Onion-designed Swindle model.
Twenty-five years ago Chris Reeve put the frame lock on the map and hasn't
let up since. This is his third generation top-selling Sebenza.
Blade-locking mechanisms come in all shapes and forms. Hogue's EX-04 (top) uses the
button lock with an additional slide safety, Buck's 110 (middle) the tried and true lockback,
and Spyderco's Southard model (bottom) uses the frame lock.
Bar The Door!
The bar lock is a simple mechanism offering astounding strength and is ambidextrous to boot. In this locking system, a round spring-loaded lock pin sits transversely across the width of the handle with enough protruding from each side to serve as a stud. The lock pin rides in a channel and when the blade is fully employed, slips into a detent in the tang, locking the blade against a rigid stop pin on the back. To release the blade, the pin is pulled downward against the spring, typically using the thumb and index finger. This allows the pin to fall out of the tang detent, which, in turn releases the blade.
Two major knife manufacturers have great success using this locking mechanism. Benchmade Knives' version, the AXIS Lock, has found its way on many of the company's folding knives and shows no sign of waning. The AXIS Lock's pin rides in a straight groove and has been used on both manual and automatic models. Likewise, SOG Knives' Arc Lock has been incorporated into many of their folders and differs slightly in that it rides in a curved or "arced" channel. Many an argument has taken place among folding knife aficionados over which is stronger, the bar lock or the frame lock, but both are rock solid. The bar lock does, however, have the advantage of being ambidextrous, and is therefore a crowd pleaser among Southpaws.
The-up-and coming lock in the folder universe is the button lock. Originally used on automatic knives, this simple locking system started raising eyebrows when upscale cutlery manufacturer William Henry adopted a manual version of the mechanism on their knives approximately 15 years ago. From an eye-appeal standpoint, the button lock is as clean as a whistle, and between the frames, the mechanism takes up little space.
The button lock system looks similar to a piston. When a spring-loaded button is depressed it pushes a drum-like sleeve away from the tang, allowing the blade to open and close. The tang works like a cam, capturing the sleeve in a detent, which holds the blade in the open position. The button is simply depressed again, clearing the tang and allowing the blade to be disengaged. More and more custom knifemakers are adopting the button lock and recently several mainstream manufacturers have incorporated it into their factory fare.
We've chosen the five most successful locking mechanisms to highlight here, but there are hosts of others out there for your inspection. It should be noted all of these designs have benefitted from the modern tactical revolution in other ways. All have either been converted or designed as 1-hand openers, either through thumb studs or flippers or both, and some have been further modified as assisted openers with street-legal spring mechanisms. Some manufacturers (as is the case with the Hogue EX-04) have fitted their folders with additional safeties. When purchasing a knife, always try to handle the merchandise before pulling the trigger. Just as it's important to pick a handle and blade style fitting your taste and needs, so it is with the lock you choose to be at the ready when you need it.
By Pat Covert
The button lock is a clean design and easy to operate in both manual and
automatic mode. Two such are the Hogue EX-04 manual model (top) and the SOG
Spec Elite II Auto (above, bottom knife). Benchmade's highly popular
Griptilian model, shown below, features the company's patented AXIS
Lock—one of the few ambidextrous lock designs available. The AXIS Lock
is simple in design and Southpaw friendly (inset). The release button
is the accessible on both sides and the pocket clip can be mounted on
either side of the handle.
The linerlock (left) has its locking leaf located inside the handle while
the frame-lock (right) uses the entire back frame slab to do the work.
Benchmade Knives
300 Beavercreek Road
Oregon City, OR 97045
(800) 800-7427
Buck Knives
660 S. Lochsa Street
Post Falls, ID 83854
(800) 326-2825
Cold Steel
3036-A Seaborg Ave.
Ventura, CA 93003
(800) 255-4716
Columbia River Knife & Tool
9720 S.W. Hillman Court, Suite 805
Wilsonville, OR 97070
(800) 891-3100
Hogue Grips
P.O. Box 1138
Paso Robles, CA 93446
(800) 438-4747
P.O. Box 800
Golden, CO 80402
(800) 525-7770
SOG Specialty Knives & Tools
6521 212th Street Southwest
Lynnwood, WA 98036
(888) 764-2378
Chris Reeve Knives
2949 S. Victory View Way
Boise, Idaho 83709
(208) 375-0367
Order Your Copy Of The GUNS Magazine June 2014 Issue Today!


text:
Can We Use the Statistical Causality with Sufficient Reliability?
Purpose of this applicative project research (ARRS L5-2329) is the identification and analysis of the key process indicators which significantly contribute to the benefits of the business processes exploitation in the company of Luka Koper, d.d. Beside that is our intention to display the importance of the systematic process approach. With this case study we attempted to get deeper understanding, and to clarify and evaluate the causalities between enablers and results. Long-term framed qualitative and quantitative analyses indicate the benefit of the identificated key processes indicators or Balanced Scorecard (BSC) and their influence on the fulfilment of the strategic directions.
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|This chapter was published in: Aleksander Janes & Slavko Dolinsek , , pages 259-266, 2011.
|This item is provided by International School for Social and Business Studies, Celje, Slovenia in its series Knowledge as Business Opportunity: Proceedings of the Management, Knowledge and Learning International Conference 2011 with number 259-266.
|Contact details of provider:
| Web page: http://www.issbs.si
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subset: commoncrawl


text:
Wabash folks on campus know James Makubuya as an associate professor of music and artistic director of WAMIDAN, the College's world music ensemble.
But long before he arrived at Wabash he was an internationally known world music performer—"world" writ large—and that reputation has only increased during his tenure here.
A musicologist who makes frequent trips back to his native Uganda to do fieldwork, James has studied with master musicians from various East African musical traditions. Though the endongo (bowl lyre) is his primary musical instrument, he is also proficient on the adungu (harp), akogo (thumb piano), ndingidi (tube fiddle), madinda (log xylophone), and in various East African dance drum styles. He has performed nationally and internationally with the New York-based African Troubadours, the Kayaga of Africa and the Kiyira Ensemble, and he has arranged traditional music for the Kronos Quartet, with which he performed in concert on the endongo.
Before coming to the U.S. he was the artistic director of CACEMCHO, Uganda's 150-voice national choir, which he led in several successful international tours, including a concert and mass celebrated by Pope John Paul II in St. Peter's Basilica in Rome. Makubuya performed on the soundtrack to the movie Mississippi Masala and several television movies and documentaries, and he has released three CDs, including The Uganda Tropical Beat I, Taata Wange and Watik, Watik: Music from Uganda.
But his most recent collaboration may be the most interesting. In 2005 he recorded Wu Man and Friends with Wu Man, the premier virtuoso on the pipa, a Chinese lute-like instrument with a 2,000-year history. His playing, singing and compositions were highlights of the CD. Joining them were masters the Appalachian-style five-string banjo and the Ukrainian bandura, and the mix was so compelling and successful that the group continues to perform from time to time.
James tries to keep a low-profile on the Wabash campus about these international collaborations and accomplishments, but you'll have a chance to enjoy his mastery of these instruments this Friday in Salter Hall during the 7:30 concert at Wally Tunes: A Symposium on Music and the Liberal Arts. His extraordinary skills and the joy he experiences and expresses are not to be missed.


text:
We restrict development in environmentally critical areas (ECAs) and areas around ECAs called buffers. Examples of ECAs include landslide-prone areas, wetlands, land next to rivers and streams (riparian corridors), and fish and wildlife habitat conservation areas.
A small project waiver allows you to do some ground disturbance for new small structures or additions to existing structures in ECAs and ECA buffers. Our waiver limits ground disturbance to:
These limits on the disturbance area include the excavation area needed for construction as well as the area of the proposed structure, including any eaves and overhangs. You must include any development since October 31, 1992 in the ground disturbance calculation for your proposed project. Once you reach the square footage maximum, you can't develop in the ECA or buffer through the small project waiver process.
If we approve your small project waiver application, you may still need an ECA review.
You can't get a small project waiver for:
You must meet these criteria to qualify for a small project waiver:
Note: In landslide-prone areas, we may require a geotechnical report showing it is safe to build on your site.
Fees for most small project waivers are based on our hourly review rate.
You must receive a small project waiver decision from us before you apply for a building permit or master use permit. Your application for a small project waiver needs to be part of a specific project. You need to complete a pre-application site visit before you submit your application. We determine if you qualify during the permit application review.
Ask Us


text:
Full-length coverage for them, peace of mind for you. Our
Swim Tights
offer waist-to-ankle UV protection without weight or bulk. They're extra durable, too, designed to be passed down from one child to the next. Best of all, these swim tights offer the sun protection you expect from Coolibar's collection of sun blocking swimwear.


text:
About the Book
In the tradition of Ruth Rendell, Lynda La Plante, Frances Fyfield, and Barbara Vine, Cut Short is a gripping psychological thriller that introduces Detective Inspector Geraldine Steel, a woman whose past is threatening to collide with her future.
D.I. Geraldine Steel relocates to the quiet rural town of Woolsmarsh, thinking she's found a restful place where she can battle her demons in private. But when she finds herself pitted against a twisted killer preying on young local women in the park, she quickly discovers how wrong she is ...
When an unwitting bystander comes forward as a witness, she quickly becomes the murderer's next obsession. And Geraldine Steel is locked in a race against time, determined to find the killer before yet another victim is discovered. But can she save the lives of the town's young women—or will Geraldine herself become the killer's ultimate trophy?
Educator and Librarian Resources
Critical Praise
Cut Short is a stylish, top-of-the-line crime tale, a seamless blending of psychological sophistication and gritty police procedure. And you're just plain going to love DI Geraldine Steel' — Jeffrey Deaver
"Russell paints a careful and intriguing portrait of a small British community while developing a compassionate and complex heroine who's sure to win fans." — Publishers Weekly
"gritty and totally addictive debut novel" — New York Journal of Books
Product Details
- Imprint: Witness Impulse
- On Sale: 12/23/2013
- Trimsize: 4.188 in (w) x 6.75 in (h) x 1.08 in (d)
- Pages: 432
- List Price: 6.99 USD
- BISAC1: FICTION / Mystery & Detective / Women Sleuths
- BISAC2: FICTION / Mystery & Detective / International Mystery & Crime
- BISAC3: FICTION / Mystery & Detective / General


text:
By Kent Gray
Triplicate staff writer
The man accused of trying to run down an attorney with his truck said in court yesterday the charges against him are lies.
Daniel William Knottnerus took the stand in his own defense and denied the charges of assault with a deadly weapon, attempted robbery, making criminal threats, battery and violating a restraining order.
The man is lying ... I deny everything McElfresh says, said a slightly agitated Knottnerus about the allegations made against him by attorney Darren McElfresh.
The allegations stem from an incident that took place on Feb. 13, 2001, when McElfresh and Anthony Gaffke Jr., a resident of the area, were on Low Divide Road near the property of Lucille Castille, whom Knottnerus works for.
Castille lost a $119,000 civil judgment the year before in which McElfresh was the attorney for the other side. Knottnerus and Castille spotted McElfresh and Gaffke sitting in a truck on Low Divide and an altercation took place.
McElfresh and Gaffke claim Knottnerus threatened to kill them and made threatening motions to ram Gaffkes truck. Both vehicles drove away, but returned minutes later.
I did everything to avoid an accident, Knottnerus said about returning to the spot and finding McElfresh exiting Gaffkes truck. I couldnt (turn) to the right because a human being was there holding something; at the time I didnt know what it was. And right in front of me was a truck I was about to hit really fast.
Knottnerus claims he swerved to the left to avoid hitting both the truck and McElfresh and slid into a gravel pile.
Darren McElfresh was headed right for me, Knottnerus said. He was running right at my truck, adding I never saw him in front of my vehicle at any time.
McElfresh reiterated his court testimony yesterday, saying there was never any question about Knottnerus intentions, a person he referred to as a loose screw.
I was very frightened, McElfresh said. I thought he was going to mow me down with his truck.
Once Knottnerus left his truck and headed toward the attorney, he claimed the camera McElfresh was holding appeared to him to be a gun.
As soon as I reached the back of my truck, I saw a flash, Knottnerus said of the camera flash. I reached out and grabbed it ... it didnt feel like a gun.
McElfresh said Knottnerus tried to wrench the camera from him, which was attached to a strap wrapped around his wrist. Knottnerus said he let go of the camera shortly after determining what it was.
I didnt say a word to him, Knottnerus said, in response to assertions that he had made death threats. Knottnerus claimed he spoke only to Gaffke, asking him to not bring McElfresh back to the area.
(See Knottnerus, Page 3A)
Another discrepancy between the parties was whether or not McElfresh wore a coat that day.
Photographs in evidence, taken by Frank Villarreal at the Del Norte County Sheriffs Department, show McElfresh in dirt-spattered clothes. He maintains they got that way while dodging Knottnerus truck.
And an area on his white shirt supposedly indicates where Knottnerus grabbed McElfresh while they struggled for the camera. Knottnerus, Castille and two other defense witnesses claim McElfresh was wearing a dark coat or jacket that day. The insinuation is that the dirt marks on the shirt were faked.
District Attorney Robert Drossel and defense counsel John Babin are scheduled to make their closing arguments this morning at the Del Norte County courthouse.


text:
SOUTH-AFRICA-IMMIGRANTS-BRITISH-L ArchivesArchiver > SOUTH-AFRICA-IMMIGRANTS-BRITISH > 2007-07 > 1183820243
From: "Dennis Pretorius" <>
Subject: [ZA-IB] Charles Edward SCOTT x Marjory MacLENNON
Date: Sat, 7 Jul 2007 16:57:23 +0200
Hallo All
I am trying to find any information about the above couple What I know at
the moment is the following:
Charles Edward SCOTT born 18 Jul 1879 in Scotland married Marjory MacLENNON.
It appears that Marjorie passed away before 1949 when Charles died in Ugie
in the Eastern Caape. He is buried in the Ugie cemetery.
According to the death Notice filed in the Cape Archives, Charles and
Marjorie had one child, Marjory Charlotte SCOTT who married Eric Bruce
SANGSTER - the were divirced in Johannesburg in 1968
I would appreciate any additional information about any of the above
people - anything at all !!
Kind regards
Dennis Pretorius, Krugersdorp, South Africa/Suid Afrika
Executive Member of GSSA / Uitvoerende Lid van GGSA
Genealogical Researcher/Genealogiese Navorser
Owner of SAGenealogy E-mail list/Lyseienaar - SAGenealogie poslys
Web address/Webadres: http://mzone.mweb.co.za/residents/k75/genealogy.html
Telephone/Telefoon: +27-83-679-8541
This thread:
|[ZA-IB] Charles Edward SCOTT x Marjory MacLENNON by "Dennis Pretorius" <>


text:
At Gemvara, we believe that the jewelry you wear should be one of a kind, like you. That's why we make each piece to order, one at a time, just the way you want it. Choose Rhodolite Garnet and Palladium or Emerald and White Gold: it's your choice. Mix and match gems and precious metals for a look that's exactly you. Gemvara uses only the highest quality materials to craft your White Gold White Sapphire Jewelry From $250 to $499 design with meticulous attention to detail. Our precious metals are recycled or responsibly mined. Brilliant natural white sapphire rivals diamond in rarity and beauty, offering the look and lasting value for less. Gemvara's white sapphire is cut for maximum brilliance.Lustrous 14k white gold is bright and eye-catching in any design. We also offer every style in premium 18 karat white gold, which has the added luxury of higher gold content. The final finishing touch to all Gemvara's white gold jewelry is plating with rhodium, a platinum group metal, for an extra bright white finish.Our wide selection of White Gold White Sapphire Jewelry From $250 to $499 by talented designers means you can find jewelry that's exactly your style. You can also shop by style, choosing our Religious, Flowers, or Bridal Collections. Gemvara's fine quality White Gold White Sapphire Jewelry From $250 to $499 is designed to be passed down for generations to come, crafted by hand in the United States.
We can help right away. Chat with a jewelry expert now!


text:
Empty Bowls Project
Empty Bowls Project has been held each year at the high school since 2011. Since March of 2011 the Senior Social II students, with the help of other District 206 students, have raised over $21,000. Money from this project has been given to local food shelves and programs such as Meals with Care, United Way Weekend Back Pack Program, the high school food shelf and the Outreach Food Shelf in Alexandria.
For more information about the Empty Bowls Project and our 2015 event contact Lynn Ransom, Youth Service Coordinator, Alexandria School District 206 – Community Education at 320-762-2142 ext. 4671.
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What is Empty Bowls?
Empty Bowls is an international grassroots effort to fight hunger. The basic premise is simple: students, potters and other crafts people, educators and others work to create handcrafted bowls. Guests are invited to a simple meal of chili and bread. In exchange for a cash donation, guests are asked to keep a bowl as a reminder of all the empty bowls in the world. The money raised is donated to organizations working to end hunger. Our project is a student led initiative sponsored by District 206 Community Education, District 206 Food and Nutrition Services and local business and service organizations.
Get involved in this event by:
· Creating a bowl for the event
· Donating a bowl for the silent auction
· Become an Empty Bowls sponsor
· Invite family and friends to join you at the event.
Student Quote: "I enjoy being part of helping the community in whatever way I can…. and the food was yummy, too!"Please view our Empty Bowls Power Point for more information.


text: The International Longshoremen's Association, AFL-CIO (ILA) and Evergreen America Corporation (EGA) ended a month long dispute with a memorandum of agreement signed this morning. The agreement contains essential terms demanded by the union on behalf of the Port Captains and Engineer whom it represents, pursuant to an NLRB certification. The striking Port Captains will promptly be returned to their jobs and to the work that they regularly performed will not be reduced, a charge that the ILA alleges had occurred. As a result of entering into this Memorandum of Agreement, the International is discontinuing its picketing of the employer's operation. The Agreement includes among other terms: provisions intended to assure the integrity and stability of the current work unit, the preservation of the unit work and jurisdiction, the company's cooperation in retaining its foreign employees who are working in the U.S., and their right to grieve and arbitrate their complaints. An important provision of the memorandum of agreement also prevents Evergreen from relocating the Port Captains beyond a 25 miles radius of the current Morristown, New Jersey office where they are housed. They will be entitled to seniority and to improvements in their wages and other terms and conditions of work which the parties intend to include in a three-year or longer agreement to be negotiated over the course of the next fourteen working days. It was agreed that issues outstanding between the parties after the fourteen days will be submitted to binding arbitration for early resolution. For the first time, the unionized employees will have input into the employer's hiring process. Until now, Evergreen was entirely at liberty in selecting, transferring and otherwise dealing with the terms and conditions of its employees. This was a key provision that the ILA won and was at the heart of the agreement. The contract will include language to assure the ILA that Evergreen will not engage in tactics designed to divert unit work to other vessels it owns or controls. The Memorandum of Agreement stipulates that Evergreen and its affiliates will immediately withdraw all pending unfair labor practice charges before the NLRB as well as pending court actions seeking damages or other relief related to the underlying dispute. Evergreen's Appeal of the Board's determination that the Port Captains and Engineer are employees entitled to representation rather than exempt managers remains in place. Evergreen was prompted to go to the bargaining table as directed by the Board in April when it faced the prospect of having its unfair labor practice charges against the ILA and its locals at East Coast ports be dismissed if not withdrawn. The NLRB's General Counsel evidently concluded yesterday that the International's job action was properly conducted in accordance with current Board law.


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text:
The Minnesota Department of Public Safety says July was the deadliest month on Minnesota roads so far this year, and last week was one of the three deadliest weeks of 2011.
Since Aug. 1, 13 people have died on state roads. The deadliest week so far this year was July 4 to July 10, when 21 people died.
There were 43 deaths in July. To date, there have been 194 traffic deaths in Minnesota. That's down from the 229 deaths at this time in 2010.
State Patrol Lt. Eric Roeske says it's not surprising to see an increase in deaths when seat belts aren't worn, when drivers speed and when they don't pay attention.
(Copyright 2011 by The Associated Press. All Rights Reserved.)


text:
Armour couple to marry
Jamie Holderby and Raymond Bigge announce their engagement.
Parents of the couple are Jim and Theresa Holderby and Marty and Cindy Bigge, all of Armour.
Jamie is a third grade teacher at Armour Elementary School.
Raymond works for the Douglas County Highway Department.
A Sept. 7 wedding is planned at United Church of Christ, Armour.


text:
Use the tools below to refine your search by only displaying reviews with a certain number of star ratings or to only show reviews from a certain time period. Eg click on '1 star' to just display the reviews we have which received a 1 star rating click or 'Within the last month' to display just reviews posted over the last month.
The Sony PSP Go seems to have many mixed reviews from consumers. Some people who have bought the Sony PSP Go say that it is better than the older PSP in respect of its size and weight. The Go is a lot lighter and more compact, although many users suggest that if you have slightly larger hands, you may find that they cramp easily. It is important to note that if you are the kind of person who enjoys buying games and then trading them in once you have got bored with them, some consumers think that you may be disappointed with the Sony PSP Go. With the Go you can only download your games at full price, and not having the option of trading them in or getting a refund.
This won't be a problem for those of you who buy games and aren't bothered with trading them in. The Go doesn't have a disc drive, so if you have any older PSP games, they will not be compatible with Go. The advantage of this is that you don't have to carry all your games around with you, which some Amazon consumers thought was ideal.
However its not all bad news, many consumer reviews have suggested that the battery life on the Go is great, and a lot of Amazon reviewers say the quality of the screen has improved vastly. With the Sony PSP Go you might get the feeling that it acts like an iPod, as it stores your pictures, allows you to watch movies, access the Internet, but unlike the iPod it was built for the gaming experience. With all this information, it is important to keep in mind that 96 of the 111 reviews on Google products for Go gave it a 3 star and above.
As rated by our community of reviewers
" Brilliant handheld console " Read More
" The People Who Control Xbox " Read More
" I love MY PS4 but it can improve " Read More
Written by guy2tr150
" Under rated " Read More
Written by jennyfalkner
" Very cool console 3D " Read More
Written by mikeskk025


text:
Let's Talk
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Meet Your Family
Our free consultation gives us the chance to meet you and your child. Here we can have an open, friendly discussion about your child's goals and find out what you hope to accomplish with one of our tutor-mentors.
Understand Your Needs
During the consultation, we conduct a cost-free and obligation free skills assessment which allows us to understand your child's learning style, personality type as well as academic strengths and weaknesses.
Build A Tailored Program
From the results of the assessment, we create a tailored program that helps us overcome any skill gaps that were identified. This program is unique to your child and will only focus on areas that need to be improved. Also, we always help with all homework, test prep, and assignments.
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Our tutor-mentors build a relationship that instills confidence and teaches tough concepts. Your child will have a new-found sense of confidence and just smile a whole lot more. You won't have to worry about them falling behind anymore. We're here to help.


text:
I was only passingly familiar with Tucker Carlson before cracking
the binding of his book, POLITICIANS, PARTISANS, AND PARASITES. I
vaguely recalled a few articles he had done for The Weekly
Standard and The American Spectator, and I knew that he
was on CNN's Crossfire. The problem is that at casa de
Hartlaub we don't really tune in to CNN all that much, and as
for Crossfire ... if I started watching James Carville with
any regularity it would be the mark of a behavior deviation so
devastating that my family would probably ship me off for that long
promised 30-day psychological evaluation. While Crossfire
appears to be on its last legs, Carlson's career trajectory is only
beginning, if POLITICIANS, PARTISANS, AND PARASITES is any
For one thing, Carlson is really funny. His written delivery is
very conversational. Reading POLITICIANS, PARTISANS, AND PARASITES
is like having this hip, smart, observant guy over for dinner and
being happy to let him monopolize the conversation for the entire
evening. Carlson is right to center right politically, but he
doesn't beat you over the head with it. He chooses his battles
wisely and almost always wins them. But POLITICIANS, PARTISANS, AND
PARASITES isn't a regurgitation of Carlson's views. It's a breezy,
entertaining account of Carlson's experiences in television
journalism and reporting.
Carlson's accounts of his adventures in the trenches of television
news journalism are not presented in an orderly fashion. It's not
quite stream of consciousness but the link between one topic and
another can be a bit tenuous. You're not really going to care,
however. Carlson is so entertaining and funny that you'll be more
than happy to sit back and let him drive at 100 words per minute
while he maintains a nonstop monologue concerning what is flying
by. His most entertaining accounts concern being on the campaign
trail with John McCain, his trip to Vietnam (again, with John
McCain), the crashing and burning of his first television program,
The Spin Room, and his dead-on descriptions of
But Carlson's literary audience will not be limited to
conservatives. Liberals who have not lost their sense of humor will
find plenty to enjoy in Carlson's accounts as well. Carlson pins
Jerry Falwell and Larry Klayman to the wall with his laser-like
scrutiny and does it so well that even if you like those gentlemen
you won't mind. Well, you will, but you'll be too busy laughing to
let it bother you for long.
POLITICIANS, PARTISANS AND PARASITES is a series of dead-on
critiques and observations of current events, television news, and
the people and personalities behind both. Its substance more than
makes up for what it lacks in organization. This is Carlson's first
book, but it hopefully will not be his last. Highly
Reviewed by Joe Hartlaub on January 22, 2011
Politicians, Partisans, and Parasites: My Adventures in Cable News


text:
In a Friday staple, we'll discuss who's in a groove and who's in a rut for the Texas Rangers.
Who's On?
Leonys Martin — The rookie center fielder has taken kindly to being the everyday guy in center. He had already pretty much established that but Craig Gentry's trip to the disabled list solidified it. Over his last five games, Martin is hitting .368 with a stolen base and his big two-homer game on Tuesday at Yankee Stadium.
Nelson Cruz — Cruz has been fairly consistent lately, which is a rare, yet good, thing for him. He's hitting .292 over the last week with a double, two homers and a team-high seven RBIs in his last six games. He mashed his 20th homer Wednesday, etching his name in Rangers history with a franchise record five straight seasons with at least 20 home runs.
A.J. Pierzynski — The veteran catcher continues to produce at the plate and work well with the Rangers' pitchers with three doubles and a homer in his last five games. He's second behind Cruz over the last six games with four RBIs.
Derek Holland — The up-and-down lefty with tons of potential turned in perhaps the best outing of his career on Thursday, pitching a two-hit, complete-game shutout in Yankee Stadium, a yard that's haunted him throughout his career.
Who's Not?
Adrian Beltre — Over his last six games, Beltre is hitting just .200 in the Rangers' cleanup spot. Don't expect this little slump to last too long, because Beltre's rarely do, but if he can pick it back up for the Rangers the offense will get only that much better.
Mitch Moreland — Since returning from the disabled list last week, Moreland has had trouble getting back to where he was before he injured his hamstring, which was a claim as one of the Rangers' best hitters this season. He's 4-for-23 in his last six games with a double and three RBIs.
Robbie Ross — Ross has worked two innings over the last week and given up two runs, including a home run to Ichiro in a game the Rangers eventually won. Ross, along with the rest of the "winning pieces" of the bullpen are being overworked at the moment, making Thursday's day off (thanks to Holland) huge for everyone.


text:
Altura Credit Union, Riverside, Calif., decorated a tree for the "Festival of Trees," an annual fundraiser held by the Riverside County Regional Medical Center. Funds raised at the event primarily go to the medical center's pediatric units. The credit union's tree was among 50 trees sold at the event. It was bought for $10,000 by the Riverside Medical Clinic and is now on display in its lobby. In addition to sponsoring its own tree, the credit union sponsored trees from 35 local schools for the "Elf's Forest" in the convention center.
Windsor Family Credit Union, Windsor, Ontario, contributed over $12,500 to assist community members in need during the holiday season. The credit union's "Joy of Giving" initiative included several events. The annual AM800 "Cans for a Cause" collected food items to benefit the St. Vincent De Paul Society. The credit union also helped provide Christmas presents to children and their families in need, $2,500 in toy purchases totalling 157 toys went to the Moose Lodge annual toy drive. Monetary donations were also made to St. Mary's Food Cupboard, Well-Come Centre for Human Potential, Windsor Homes Coalition Inc. and Family Services Windsor Essex.
MECU, Baltimore, selected toys and other gifts for the children of the Salvation Army Angel Tree. The credit union's team made Christmas special for 125 children in the Baltimore area by shopping for toys, clothes and other basics. The value of the presents donated totaled over $11,000.
Security Service Federal Credit Union, San Antonio, opted to honor military men and women this holiday season as a sponsor of more than 700 military greetings airing on local television stations. The credit union's sponsorship allowed military personnel and their families stationed around the world to extend greetings throughout the holidays to family members living in several Texas and Colorado cities.
Charter Oak Federal Credit Union Groton, Conn., donated to several organizations this holiday season through its Community Outreach Program. Donations were made to Books for Dreams, Kids for Christmas, Colectivo Mestizal, MALTA, Bethsaida Community Inc., Holy Family Shelter Inc., WARM, the Friends of Assisi Food Pantry and the March of Dimes. The program also donated $2,000 worth of turkeys to the Gemma Moran Food Center.
Option 1 Credit Union Grand Rapids, Mich., elected to forgo a staff holiday party and instead support area food pantries. The credit union helped kick off the Spartan Stores, D&W and Family Fare's Scan Away Hunger program with a monetary donation of $1,000.
Cabrillo Credit Union, San Diego, donated over $300 worth of nonperishable food items to benefit St. Vincent De Paul. After hearing that food donations were down this year, the credit union's staff rallied to hold a food drive before the traditional holiday season. The food items were collected from nearly 60 employees through an organization-wide donation drive.
Hawthorne Credit Union, Naperville, Ill., collected and donated 570 pounds of personal health and hygiene items, snacks and holiday keepsakes to Operation Support Our Troops of Illinois to be inserted into Christmas stockings and shipped to U.S. soldiers fighting in Iraq and Afghanistan. In addition, the credit union raised $170 in cash donations from an employee jeans day and other donations, which will be used to ship the packages to the troops.
Saugus Federal Credit Union, donated food and other items for holiday baskets distributed to local families in need. Each basket contained a turkey and over 20 pounds of additional food items purchased by credit union staff. The credit union has held the event for the past 19 years.
Security Service Federal Credit Union, San Antonio, joined with former San Antonio Spurs and two-time NBA All-Star Sean Elliott and his wife, Claudia Zapata, to collect turkeys to put on the plates of hungry families in Southwest Texas. In addition to calling for support from the community, the couple donated 50 turkeys to the cause. In all, 500 turkeys were collected to benefit the San Antonio Food Bank.


text:
Le cartel Hypnoweb a besoin de toi !
Rejoins-nous sans attendre
Entre les annonces officielles et d'autres officieuses, voici comment les acteurs ont réagi à l'annonce de la fin de de Merlin.
Colin Morgan (communiqué officiel de la BBC)
"From the beginning this was always going to be a five year journey that we embarked on and I think the show has run its natural course. The show has grown and grown each year and now we've arrived at its strongest point and we've achieved what we set out to do… I know this is the end, and I know this is goodbye, but thank you for being there on the journey with us because it has been a lot of fun!"
> Interview (vidéo)
Katie McGrath (communiqué officiel de la BBC)
"I have always said the success of the show has stemmed from our audience being able to relate to the characters on different levels - being based on the universally loved Arthurian legend is only a tiny part of its success - it's a story about acceptance and growing up. The breathtaking finale of this series leaves you with no doubt that characters have been on their journeys and had their stories told - it's completely the right time to draw our telling of the story to a close."
Anthony Head (Digital Spy)
"Hats off to Julian and Johnny, the producers, for sticking to their guns with the five-season story arc of Merlin. It would have been too easy to give in to demand and stretch the show on beyond their original plan because of its incredible success. Instead, Merlin finishes at the height of its success and will, therefore, live on in people's memory. That's certainly what happened with Buffy - and it really doesn't happen that often.
"As for myself, I really miss working with such a talented and warm-hearted bunch of people - cast, crew, production. Everyone in London, Wales and France made the Merlin experience a very, very special one. Thank you all."
Eoin Macken sur Twitter
Un internaute lui a écrit :
"sad 2 see Merlin is ending after 5 years. It had so much potential but ultimately this last series has failed. @eoincmacken u gunna miss it?"
La réponse d'Eoin :
"@goldfishboogie honestly? Well, I loved Merlin and everything about it and everybody....BUT I agree with what u just said about this series."
Et de manière plus générale, voici ce qu'il a déclaré :
"For the ppl sad about Merlin,it's true this is the end of it, sorry about that...if I'd my way the knights would be flying superheroes ..."
Alexander Vlahos sur Twitter
"To those mourning the loss of Merlin from our screens, I guarantee the last 5 eps are something special. Proud to have been a part of it. X"
Rupert Young sur Twitter
"It's official! Has been an honour being part of such a great show. Thanks to everyone for their support-will miss it as much as you all x"
"Spoiler alert:-Sir Leon leaves Camelot and starts a hugely successful restaurant chain in Brussels!! pic"


text: January 2, 2014 SHARE Tonight's edition of Impact Wrestling will feature the following, according to ImpactWrestling.com: – Tonight on IMPACT, TNA President Dixie Carter will present the official coronation of the NEW World Heavyweight Champion, Magnus! In true British style, Carter plans to give her champion the complete royal treatment in his first appearance with the World Title! However, will there be any uninvited guests that decide to crash the coronation of Magnus? Tune in Thursday to find out. – The X Division Championship will be on the line on Thursday night as new titleholder Austin Aries battles Chris Sabin in a rematch! Don't miss two of the premiere X Division superstars setting the bar for nonstop action in 2014 with the X Title at stake! – Olympic gold medalist and multi-time World Champion Kurt Angle has informed TNA officials that he will make an announcement on IMPACT about his future in wrestling. Rumors have been swirling for weeks ever since Kurt lost to Bobby Roode once against at Final Resolution- what will he announce to the wrestling world? Tune in and find out! – Also on IMPACT: Bully Ray will battle Joseph Park, Gail Kim's ongoing Open Challenge, plus the TNA in-ring debut of Samuel Shaw! All this and much more on Thursday's IMPACT WRESTLING broadcast on SpikeTV at 9/8c! From his beginnings in TNA, to the British Invasion tag team, his role in the Main Event Mafia, proving himself to Sting, and then winning the championship, watch how Magnus ascended to the top of TNA Wrestling. SHARE ON FACEBOOK SHARE ON TWITTER 1/1 WWE Main Event Videos: MizTV with Brodus Clay, Kingston vs Sandow, Divas Tag Team Match Brodus Clay New Look (Photo), Brie Bella Talks Daniel Bryan Joining Wyatt Family, Ted DiBiase Sr. Hypes Old School Raw Austin Ariesbobby roodechris sabingunnerimpact wrestlingJames StormKurt AngleMagnusTNA Have a news tip? Attended an event and want to send a live report? Submit it now!


text:
Today is the first day of winter.
I want to celebrate this season with one of mine illustration
Gheburaseyeconfidential info
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text:
News from the Bench
Discover what's going on at CST, receive our latest application notes and tips, read our science features, and learn about our products.
To Purchase # 14679S
|100 µl (10 western blots)
Find answers on our FAQs page.
PhosphoSitePlus® Resource
- Additional protein information
- Analytical tools
Mono-Methyl Lysine [mme-K] MultiMab™ Rabbit mAb mix #14679
Western blot analysis of MCF7 cells, untreated (-) or treated with adenosine-2',3'-dialdehyde (AdOx, 100 μM, 24 hr; +), using Mono-Methyl Lysine [mme-K] MultiMab™ Rabbit mAb mix (upper), and GAPDH (D61H11) XP® Rabbit mAb #5174 (lower).Learn more about how we get our images
Gallery: Mono-Methyl Lysine [mme-K] MultiMab™ Rabbit mAb mix #14679
Western Blotting Protocol
For western blots, incubate membrane with diluted primary antibody in 5% w/v nonfat dry milk, 1X TBS, 0.1% Tween® 20 at 4°C with gentle shaking, overnight.
NOTE: Please refer to primary antibody datasheet or product webpage for recommended antibody dilution.
A. Solutions and Reagents
NOTE: Prepare solutions with reverse osmosis deionized (RODI) or equivalent grade water.
- 20X Phosphate Buffered Saline (PBS): (#9808) To prepare 1 L 1X PBS: add 50 ml 20X PBS to 950 ml dH2O, mix.
- 10X Tris Buffered Saline (TBS): (#12498) To prepare 1 L 1X TBS: add 100 ml 10X to 900 ml dH2O, mix.
- 1X SDS Sample Buffer: Blue Loading Pack (#7722) or Red Loading Pack (#7723) Prepare fresh 3X reducing loading buffer by adding 1/10 volume 30X DTT to 1 volume of 3X SDS loading buffer. Dilute to 1X with dH2O.
- 10X Tris-Glycine SDS Running Buffer: (#4050) To prepare 1 L 1X running buffer: add 100 ml 10X running buffer to 900 ml dH2O, mix.
- 10X Tris-Glycine Transfer Buffer: (#12539) To prepare 1 L 1X Transfer Buffer: add 100 ml 10X Transfer Buffer to 200 ml methanol + 700 ml dH2O, mix.
- 10X Tris Buffered Saline with Tween® 20 (TBST): (#9997) To prepare 1 L 1X TBST: add 100 ml 10X TBST to 900 ml dH2O, mix.
- Nonfat Dry Milk: (#9999).
- Blocking Buffer: 1X TBST with 5% w/v nonfat dry milk; for 150 ml, add 7.5 g nonfat dry milk to 150 ml 1X TBST and mix well.
- Wash Buffer: (#9997) 1X TBST.
- Primary Antibody Dilution Buffer: 1X TBST with 5% nonfat dry milk; for 20 ml, add 1.0 g nonfat dry milk to 20 ml 1X TBST and mix well.
- Biotinylated Protein Ladder Detection Pack: (#7727).
- Prestained Protein Marker, Broad Range (11-190 kDa): (#13953).
- Blotting Membrane and Paper: (#12369) This protocol has been optimized for nitrocellulose membranes. Pore size 0.2 µm is generally recommended.
- Secondary Antibody Conjugated to HRP: Anti-rabbit IgG, HRP-linked Antibody (#7074).
- Detection Reagent: SignalFire™ ECL Reagent (#6883).
B. Protein Blotting
A general protocol for sample preparation.
- Treat cells by adding fresh media containing regulator for desired time.
- Aspirate media from cultures; wash cells with 1X PBS; aspirate.
- Lyse cells by adding 1X SDS sample buffer (100 µl per well of 6-well plate or 500 µl for a 10 cm diameter plate). Immediately scrape the cells off the plate and transfer the extract to a microcentrifuge tube. Keep on ice.
- Sonicate for 10–15 sec to complete cell lysis and shear DNA (to reduce sample viscosity).
- Heat a 20 µl sample to 95–100°C for 5 min; cool on ice.
- Microcentrifuge for 5 min.
Load 20 µl onto SDS-PAGE gel (10 cm x 10 cm).
NOTE: Loading of prestained molecular weight markers (#13953, 10 µl/lane) to verify electrotransfer and biotinylated protein ladder (#7727, 10 µl/lane) to determine molecular weights are recommended.
- Electrotransfer to nitrocellulose membrane (#12369).
C. Membrane Blocking and Antibody Incubations
NOTE: Volumes are for 10 cm x 10 cm (100 cm2) of membrane; for different sized membranes, adjust volumes accordingly.
I. Membrane Blocking
- (Optional) After transfer, wash nitrocellulose membrane with 25 ml TBS for 5 min at room temperature.
- Incubate membrane in 25 ml of blocking buffer for 1 hr at room temperature.
- Wash three times for 5 min each with 15 ml of TBST.
II. Primary Antibody Incubation
- Incubate membrane and primary antibody (at the appropriate dilution and diluent as recommended in the product datasheet) in 10 ml primary antibody dilution buffer with gentle agitation overnight at 4°C.
- Wash three times for 5 min each with 15 ml of TBST.
- Incubate membrane with Anti-rabbit IgG, HRP-linked Antibody (#7074 at 1:2000) and Anti-biotin, HRP-linked Antibody (#7075 at 1:1000–1:3000) to detect biotinylated protein markers in 10 ml of blocking buffer with gentle agitation for 1 hr at room temperature.
- Wash three times for 5 min each with 15 ml of TBST.
- Proceed with detection (Section D).
D. Detection of Proteins
Directions for Use:
- Wash membrane-bound HRP (antibody conjugate) three times for 5 minutes in TBST.
- Prepare 1X SignalFire™ ECL Reagent (#6883)by diluting one part 2X Reagent A and one part 2X Reagent B (e.g. for 10 ml, add 5 ml Reagent A and 5 ml Reagent B). Mix well.
- Incubate substrate with membrane for 1 minute, remove excess solution (membrane remains wet), wrap in plastic and expose to X-ray film.
* Avoid repeated exposure to skin.
posted June 2005
revised November 2013
Western Blot Reprobing Protocol
Reprobing of an existing membrane is a convenient means to immunoblot for multiple proteins independently when only a limited amount of sample is available. It should be noted that for the best possible results a fresh blot is always recommended. Reprobing can be a valuable method but with each reprobing of a blot there is potential for increased background signal. Additionally, it is recommended that you verify the removal of the first antibody complex prior to reprobing so that signal attributed to binding of the new antibody is not leftover signal from the first immunoblotting experiment. This can be done by re-exposing the blot to ECL reagents and making sure there is no signal prior to adding the next primary antibody.
A. Solutions and Reagents
NOTE: Prepare solutions with reverse osmosis deionized (RODI) or equivalently purified water.
- Wash Buffer: Tris Buffered Saline with Tween® 20 (TBST-10X) (#9997)
- Stripping Buffer: To prepare 100 ml, mix 6.25 ml of 1M Tris-HCl pH 6.8, 10 ml of 20% SDS and 700 μl β-mercaptoethanol. Bring to 100 ml with deionized H20. Make buffer fresh just prior to use.
B. Protocol
- After film exposure, wash membrane four times for 5 min each in TBST. Best results are obtained if the membrane is not allowed to dry.
- Incubate membrane for 30 min at 50°C in stripping buffer (with slight agitation).
- Wash membrane six times for 5 min each in TBST.
- (Optional) To assure that the original signal is removed, wash membrane twice for 5 min each with 10 ml of TBST. Incubate membrane with LumiGLO® with gentle agitation for 1 min at room temperature. Drain membrane of excess developing solution. Do not let dry. Wrap in plastic wrap and expose to x-ray film.
- Wash membrane again four times for 5 min each in TBST.
- The membrane is now ready to reuse. Start detection at the "Membrane Blocking and Antibody Incubations" step in the Western Immunoblotting Protocol.
posted June 2005
revised June 2016
|Western Blotting
Mono-Methyl Lysine [mme-K] MultiMab™ Rabbit mAb mix recognizes endogenous levels of protein only when mono-methylated at a lysine residue. Although this antibody shows minimal cross-reactivity to di-methyl lysine by ELISA, it does not cross-react with endogenous levels of methylated arginine or di- or tri-methylated lysine by western blot.Species Reactivity: All Species Expected Species predicted to react based on 100% sequence homology: All Species Expected
MultiMab™ rabbit monoclonal antibody mixes are prepared by combining individual rabbit monoclonal clones in optimized ratios for the approved applications. Each antibody in the mix is carefully selected based on motif recognition and performance in multiple assays. Each mix is engineered to yield the broadest possible coverage of the modification being studied while ensuring a high degree of specificity for the modification or motif.
Methylation of lysine residues is a common regulatory posttranslational modification (PTM) that results in the mono-, di-, or tri-methylation of lysine at ε-amine groups by protein lysine methyltransferases (PKMTs). Two PKMT groups are recognized based on structure and catalytic mechanism: class I methyltransferases or seven β strand enzymes, and SET domain-containing class V methyltransferases. Both use the methyl donor S-adenosyl-L-methionine to methylate histone and non-histone proteins. Class I methyltransferases methylate amino acids, DNA, and RNA (1,2). Six methyl-lysine-interacting protein families are distinguished based on binding domains: MBT, PHD finger, Tudor, PWWP, WD40 repeat, and chromodomains. Many of these display differential binding preferences based on lysine methylation state (3). KDM1 subfamily lysine demethylases catalyze demethylation of mono- and di-methyl lysines, while 2-oxoglutarate-dependent JmjC (KDM2-7) subfamily enzymes also modify tri-methyl lysine residues (4).
Most PKMT substrates are histone proteins and transcription factors, emphasizing the importance of lysine methylation in regulating chromatin structure and gene expression. Lys9 of histone H3 is mono- or di-methylated by G9A/GLP and tri-methylated by SETDB1 to activate transcription. JHDM3A-mediated demethylation of the same residue creates mono-methyl Lys9 and inhibits gene transcription (5). Tumor suppressor p53 is regulated by methylation of at least four sites. p53-mediated transcription is repressed following mono-methylation of p53 at Lys370 by SMYD2; di-methylation at the same residue further inhibits p53 by preventing association with 53BP1. Concomitant di-methylation at Lys382 inhibits p53 ubiquitination following DNA damage. Mono-methylation at Lys382 by SET8 suppresses p53 transcriptional activity, while SET7/9 mono-methylation at Lys372 inhibits SMYD2 methylation at Lys370 and stabilizes the p53 protein. Di-methylation at Lys373 by G9A/GLP inhibits p53-mediated apoptosis and correlates with tri-methylation of histone H3 Lys9 at the p21 promoter (1,6). Overexpression of PKMTs is associated with multiple forms of human cancer, which has generated tremendous interest in targeting protein lysine methyltransferases in drug discovery research.
1. Lanouette, S. et al. (2014) Mol Syst Biol 10, 724.
2. Clarke, S.G. (2013) Trends Biochem Sci 38, 243-52.
3. Herold, J.M. et al. (2011) Curr Chem Genomics 5, 51-61.
4. Thinnes, C.C. et al. (2014) Biochim Biophys Acta 1839, 1416-32.
5. Klose, R.J. et al. (2006) Nature 442, 312-6.
For Research Use Only. Not For Use In Diagnostic Procedures. Cell Signaling Technology is a trademark of Cell Signaling Technology, Inc. MultiMab is a trademark of Cell Signaling Technology, Inc. XP is a registered trademark of Cell Signaling Technology, Inc. Tween is a registered trademark of ICI Americas, Inc. Use of Cell Signaling Technology (CST) Motif Antibodies within certain methods (e.g., U.S. Patents No. 7,198,896 and 7,300,753) may require a license from CST. For information regarding academic licensing terms please have your technology transfer office contact CST Legal Department at email@example.com. For information regarding commercial licensing terms please contact CST Pharma Services Department at firstname.lastname@example.com.


text:
How To Apply For Georgia COMPASS Food Stamp Benefits Online?
Food stamp is nutrient aid to the children families and disable people that can not afford food. government has plan this program for low income families, refugees and victims of the natural disaster can get the food at free of cost. In order of getting the benefits, you need to have applied for food stamps.
About Georgia Compass
Georgia food stamp program is giving electronically Benefit security cards and EBT Cards to the families who deserve for food help. This program usually helps those household individuals that have low income and limited earning sources. In this way, the low income families can receive the food stamps benefits to promote the healthy eating, lifestyles and employment as well.
Detailed Instructions:
- Visit www.compass.ga.gov.
- It allows the customers to apply for benefits online and also view the potential eligibility by using the pre-screening tools. Click on the link apply for benefits and choose start a new application, if you don't have started this process before and click on next button.
- Fill out the form for "Income Limits and Verification" and click on next.
- Next you would have been asking for "login", 'signup" and "without signup option". Choose the one best suited to you.
- 4 steps signup will give you many benefits, just provide "your name", "user id & password" , "secrets questions" and "agreement"
- The peoples who have an account in Georgia can check their status of application online.
- When you apply online, they will conduct the meeting via telephone interview.
- You will provide the proof of identity.
- Proof yourself for citizenship by providing the birth certificate, hospital record or U.S passport.
- Social security number is essential to apply for benefits.
- You will provide the proof of income for every household member.
- You need to have provided the rent receipt and mortgage payment paper.
- You can give them the medical bills of a person who have at least 60 ages and handicap.
- The additional information may also require for qualifying; it is depend upon your financial situation.
- Call at 1-877-423-4746 in case of any difficulty.
Off Line Method:
Step 1. Download The Application:
- Fill out the application accurately by giving answers of questions, contact them for any sort of assistance as mentioned in application.
- Finally sign & date the filled application.
Step 2. Post The Application
- Save a copy of page one for yourself,
- Mail, fax, or visit office local Department of Family & Children Services (DFCS) office with pages 3–5 application to your. Get the guide of your reeving benefits from them.
- Check FAQs for any confusion.
When you are considered to be eligible then you can get the benefits within 30 days. In order to get the benefit program, they will send you an EBT card and PIN code. The household individuals use this card in authorized shops to buy food.
Everyone can apply for the food stamp benefits that have limited resources and face the crisis. After applying they can purchase food from the authorized food stores. The transaction may deduct from the EBT card that provided the government of Georgia to the residents for benefits. These services are free and available for those who need them most.


text:
Ark. lawmakers return with focus on Medicaid
LITTLE ROCK, Ark. (AP) - Arkansas lawmakers are returning for the fourth week of the legislative session, with the future of the state's compromise Medicaid expansion still uncertain.
The House and Senate are set to convene on Monday, while an impasse over the "private option" funding bill stretches into its third week. Approved as an alternative expanding Medicaid under the federal health law, the private option is the state's plan to use federal Medicaid funds to purchase private insurance for low-income residents.
The Senate has approved reauthorizing the program, but the legislation has stalled before the state House. It's unclear when the House will vote again on the bill.
Some private option opponents are considering a compromise plan to support the legislation if state officials agree to seek federal approval for a limited enrollment period.Copyright 2014 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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National Railway (NRZ) of Zimbawe's HIV/AIDS Prevention Program
Hope Chigudu, Wilfred Ncube Tichagwa, Virginia Phiri
Serier Sida EvaluationDescription:
Sida Evaluation 03/17 / National Railways of Zimbabwe is a large parastatal employing about 10.000 people. In 1992 a policy to promote HIV/AIDS awareness and prevention at the workplace was introduced.
Sida has supported the programme jointly with NRZ since July 2000.
The evaluation was carried out as follows: Discussion on the TOR with programme coordinator, focussed one-to-one interviews with managers and programme coordinator, focussed group discussions with peer educators and peers including SWOT analysis and use of documents relevant for the evaluation.
The programme has been largely effective in meeting implementation targets but peer educator activities targeting employees and dependants were far below targets. Socio-cultural factors of sexual behaviour have not been addressed as yet and this might be the reason for why the change from high-risk sexual behaviour to a low one has been somewhat slow. The adoption of result oriented planning methods is recommended.
- Download: National Railway (NRZ) of Zimbawe's HIV/AIDS Prevention Program
- Filesize: 245,25 KB


text:
Compariosn between different Object XML Binding Framework (3 messages)
I have to generate the classes from schema (XSD). Then I have to unmarhsall the XML into objects and then marshall the objects to XML. I have looked for various framework supporting that. I have looked for JAXB, Castor, XMLBeans, JIBX, Quick and Zeus. The finding are as: 1. Quick and Zeus does not support the class generation from XSD, only supports class generation from DTD. 2. JIBX does not support class generation from schema having enumeration or restriction tag. 3. JAXB supports generation of classes but could not unmarshall the XML (provided to me, although it supports unmarshalling from other XMLs), as XSD have only complex types, so could not generate the classes corresponding to the root element. So failed due to the binding problem with the XML provided to me. 4. Castor and XMLBeans are working fine. I am confused to use which of the approach. The problem is with the memory. I have run a lot of tests and have found that performance of XMLBeans is far better compared to Castor, but for larger XML (>20MB) the castor works fine but XMLBeans throws OutOfMemory Error. The observations are: ------------------------------- Memory| Castor | XMLBeans ------------------------------- 10MB | 10 sec | 3 sec 22MB | 16 sec | Failed 32MB | 18 sec | Failed 42MB | Failed | Failed The size of XML could be large, could anyone suggests how to improve the performance of castor or how could XMLBeans supports the much bigger XML. The heap memory allocated is 256MB and that is fixed.
- Posted by: Amit Arora
- Posted on: November 15 2007 00:45 EST
Threaded Messages (3)
- Fix the Schema, then try again by Anthony Coates on November 15 2007 03:48 EST
- Re: Fix the Schema, then try again by Amit Arora on November 15 2007 04:23 EST
- What does the *whole* Schema look like? by Anthony Coates on November 22 2007 07:28 EST
- Re: Fix the Schema, then try again by Amit Arora on November 15 2007 04:23 EST
Fix the Schema, then try again[ Go to top ]
It sounds like JAXB wouldn't compile your Schema because it didn't have at least one global element definition to act as the document root. If that is the case, your Schema won't be able to validate any of your XML documents. You have to have at least one global element definition in a Schema to make it usable. Sorry if this is a stupid question, but have you actually validated your XML examples directly against the Schema? It wasn't obvious from the text whether you have, and your description of the Schema suggests that it wouldn't validate your examples. If it does validate them without errors, then something hasn't been properly described, and I would need more information to be able to say more. Cheers, Tony. -- Author, XML APIs chapter, "Advanced XML Applications from the Experts at The XML Guild" http://www.amazon.com/Advanced-XML-Applications-Experts-Guild/dp/1598632140/ref=sr_1_1?ie=UTF8&s=books&qid=1195115964&sr=1-1
- Posted by: Anthony Coates
- Posted on: November 15 2007 03:48 EST
- in response to Amit Arora
Re: Fix the Schema, then try again[ Go to top ]
My XSD is like: The root element here is 'index', but the JAXB generated the class for IndexType. There is no class corresponding to 'index' like Index.java . This is creating the problem with binding the XML into objects. So I have tried with Castor and XMLBeans. They are generating the class that could be used to unmarshall. I have validated the XML against the XSD and that is working fine. But the tradeoff between them is performance and memory. So I like to know how could we imporve the performance using castor or how could memory allocation problem be handled using castor.
- Posted by: Amit Arora
- Posted on: November 15 2007 04:23 EST
- in response to Anthony Coates
What does the *whole* Schema look like?[ Go to top ]
Could you post the entire Schema? Thanks, Tony.
- Posted by: Anthony Coates
- Posted on: November 22 2007 07:28 EST
- in response to Amit Arora


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JOHNS CREEK, Ga. – Johns Creek's economic development corporation – Johns Creek Advantage – last week announced that JCA had raised $1.453 million in private and public pledge "investments" that will fund the organization through 2017. JCA said that this amount is 116 percent of the $1.25 million goal.
The "Victory Celebration," held at Country Club of the South in Johns Creek, was attended by nearly 100 private and public sector leaders who have supported the JCA campaign and who will be influential in carrying out the organization's mission. JCA leadership publicly thanked Country Club of the South for its generosity in hosting the event.
The program chronicled the evolution of JCA, highlighted JCA's critical role as an economic driver and included the formal introduction to the community of newly hired President and Chief Executive Officer Courtney Bernardi.
Speakers included Neil Stevens, JCA Board chairman and executive vice president and chief operating officer of KeyWorth Bank; Tom Tate, JCA Board chair-elect and president of the law firm of Andersen, Tate and Carr; Mayor Mike Bodker; Bernardi; and Craig McCoy, JCA immediate past chair and CEO of Emory Johns Creek Hospital.
In the coming months, Bernardi and her team at JCA will deploy campaign funds to ramp up JCA's economic development program with primary goals of growing businesses and jobs in Johns Creek, stimulating capital investment and sustaining the outstanding quality of life enjoyed by Johns Creek residents.
Johns Creek Advantage is a 501(c)(3) economic development organization for the city of Johns Creek. For information, contact JCA Coordinator Bethany Lavigno at email@example.com or Bernardi at firstname.lastname@example.com, or call 404-937-6450. To become an investor in JCA, contact Campaign Director Sean Mikula at 404-550-6167 or email@example.com.


text: Every brand on Facebook is on Facebook for one reason — to (eventually) get more business. But getting more business from Facebook means different things to different types of businesses. Different brands will have different objectives, such as driving in-store sales, increasing online sales, launching a new product, building awareness, or promoting a mobile app. Regardless of the objective, there are a few steps that happen before Facebook fans can turn into real business. You have to first build an audience on Facebook, then drive inbound traffic to your website, then turn that traffic into qualified leads, and then nurture those leads into customers. How do you build audience on Facebook? The answer is to gain a lot of Facebook likes. Well! For a new page or post it is difficult to gain a lot of likes. You need thousands of likes to gain popularity on Facebook. Other than having an interesting post, knowing how to grab the audience is also important. Buy 500 Facebook Likes cheap and fast as likes induce likes. When people visit your page or post and see a lot of likes, it will automatically grab their attention and there is a chance they end up liking your post which of course increases your likes! This is how it works. At Followerscheap you can buy 500 Facebook likes at the click of a button


text:
Game changer
Penny has a strong track record of picking winners from the healthcare and diagnostics market and he sees the near-term prospect of cash generation from the Heparin PF4 product.
This test screens for allergies to a widely used blood thinner, Heparin, which affects some 12 million people in the US. The study for this will commence within the next two to three months and Penny is excited about its prospects.
Last week, Citywire AAA-rated Penny doubled his stake from 14,000 to 28,035,000 shares in the group, taking his ownership of the company to 16.61%.
Penny has none in his L&G UK Alpha Trust as a minimum stake in there would need to be around 4%, but he has put the stock into his life product equivalent.
Akers is currently trading at 3.75p but its broker Daniel Stewart has upgraded its target price from 6p to 10p and calculates some 82% upside following the placing.
Penny told Citywire: 'There is enough there to make this exciting. They have some products with big potential and are funded for the next 12 months.
Penny tips the Heparin allergy testing product to bring in near-term cash. Indeed, it could be the 'game changer', he says.
As per our Terms of Use, Stockopedia is a financial news & data site, discussion forum and content aggregator. Our site should be used for educational & informational purposes only. We do not provide investment advice, recommendations or views as to whether an investment or strategy is suited to the investment needs of a specific individual. You should make your own decisions and seek independent professional advice before doing so. The author may own shares in any companies discussed, all opinions are his/her own & are general/impersonal. Remember: Shares can go down as well as up. Past performance is not a guide to future performance & investors may not get back the amount invested.
Akers Biosciences, Inc. develops, manufactures and supplies point-of-care screening and testing products designed to bring health-related information to the patient or clinician. The Company's product offerings and pipeline products focus on delivering diagnostic assistance in a range of healthcare fields/specialties, including cardiology/emergency medicine, metabolism/nutrition, diabetes, respiratory diseases and infectious diseases detection, as well as for on and off-the-job alcohol safety initiatives. The Company's primary focus is the development and sale of disposable diagnostic testing devices that can be performed in minutes, to facilitate time sensitive therapeutic decisions. The Company's main products include a disposable breathalyzer test that measures the blood alcohol content of the user, a rapid test detecting the antibody causing an allergic reaction to Heparin and a disposable breathalyzer test that measures Free Radical activity in the human body. more »
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|11th Apr '11
|1 of 1
this share is going from strength to strength....... the final results give a great insight into all the products and the financials are improving dramatically.
|| Link | Share


text:
Argument Against Auto
Presso Hand-Pressed Espresso Maker
Does the much fabled "perfect pull" exist? We may never know. But rest assured that espresso aficionados and crema-snobs are, like all gear heads, on the search.
Besides finding the perfect bean, the most contended aspect of great espresso is the machine (and its operator) and therein lies the genius of the Presso Espresso Maker ($150). Leaving little margin for error the Presso is designed to work without any electricity. Pack your favorite ground (as fresh as possible), pour boiling water into the reservoir, and press. No electricity, no capsules, no fuss. Presso even includes a manual milk frother for your Sunday afternoon cappuccino, served powerless. Oh, and don't go thinking the Presso is just another fancy kitchen gadget to complement your Kitchen-Aid (irony of our photo acknolwedged), the Presso's rugged design makes it a worthy addition to your next camping excursion.
Buy Now: $150


text:
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Dell enhances security portfolio
At the Dell Enterprise Forum customer and partner event last week, Dell showcased new security services and solutions that further expand its security portfolio. With the new offerings, businesses can defend all technology touch points to better safeguard the corporate network, critical data and devices while enabling employee productivity and confidently protecting the mobile workforce.
As security threats continue to evolve and multiply, organisations are struggling to both keep pace with major technology trends such as BYOD, cloud and mobility, and defend their perimeter. The frequency of attacks is expanding at an alarming rate globally. In fact, Dell prevented 1,06-trillion intrusion events in 249 countries in the past year alone.
A Dell global security survey released in February found that 74% of global respondents had experienced a security breach in the past year, but on average, respondents only allocated 17% of their IT budget to security.
In order for organisations to truly transform their business, it is imperative they ensure data is protected and their workforce is productive. In today's world, that means protection at the data centre, in the cloud, within the network and especially at the endpoint.
According to a recent Forrester Research report: "Employee endpoints are frequent targets of cybercriminals, and gaining control of the endpoint provides easy access to some of the organisation's most sensitive data assets. Forrester believes that any comprehensive data security strategy must include both reducing the endpoint threat surface and limiting exposure to data loss involving these endpoints."
"In today's evolving technology landscape, organisations face an unprecedented number and variety of security threats. Only a connected approach to security protects an organisation's entire IT environment without compromising access, collaboration, performance or cost," says Brad Pulford, Enterprise Solutions Group Director, Dell.
"Our portfolio updates shared today will help customers implement a holistic security strategy to protect their businesses from the outside-in and inside-out. Ultimately, Dell's differentiated security approach allows businesses to defend all technology touch points from the device to the data centre to the cloud."
Dell SecureWorks, an industry leader in information security services, launched a new, cutting-edge Advanced Endpoint Threat Detection (AETD) managed service.
The AETD solution is the latest addition to Dell SecureWorks' Advanced Threat Services portfolio – a comprehensive suite of Internet security services that combat advanced cyber threats – which features the Managed Advanced Malware Protection (MAMP) service and the Targeted Threat Hunting service.
Many of the most devastating security breaches to date resulted from attacks originating at one or more endpoints of the victim organisation. Companies hosting valuable data require multiple layers of security, including a 24×7 endpoint threat detection solution, in order to thwart shifting threats.
Dell's AETD service has a number of threat-oriented features:
The updated Dell Secure Mobile Access (SMA) solution provides organisations with per-app VPN access to enterprise data and resources, while protecting the corporate network from security threats. The BYOD migration and increase of both employee-and employer-owned mobile devices in the workplace has resulted in a mandate for IT to enable secure mobile access to corporate data and resources.
By enabling IT to restrict VPN access only to a set of trusted mobile applications, Dell's SMA solution is designed to manage and secure access to business applications and data, while coexisting with personal applications and respecting personal data privacy.
While the potential for security breaches and the introduction of malware into the network can result from any type of mobile access, the risk intensifies with the co-mingling of business and personal data and applications when employees use personal devices for work.
Dell's SMA solution combines a Dell SonicWALL E-Class Secure Remote Access Appliance powered by the new Secure Mobile Access Operating System 11.0, with the Dell SonicWALL Mobile Connect 3.1 mobile application, to enable IT to easily provision secure mobile access and role-based privileges for both managed and unmanaged devices for tens of thousands of users.
Additional benefits include:
Dell's new Dell Data Protection | Hardware Crypto Accelerator (HCA) extends the current Dell Data Protection | Encryption portfolio and helps customers rest assured that their data is secured in accordance with the highest enforceable standards.
With FIPS 140-2 level 3 certification – the "Fort Knox" of client protection – HCA supports Dell's mission to provide agile, manageable and effective solutions to secure endpoints for IT infrastructures of all sizes through a number of advancements:


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Remediation of Working Memory in Schizophrenia
This study has been completed.
VA Office of Research and Development
ClinicalTrials.gov Identifier:
First Posted: October 15, 2009
Last Update Posted: April 25, 2016
Veterans Medical Research Foundation
Minneapolis Veterans Affairs Medical Center
Information provided by (Responsible Party):
VA Office of Research and Development
- Full Text View
- Tabular View
- Study Results
- Disclaimer
- How to Read a Study Record
The primary aim of the study is to test the efficacy of a novel cognitive remediation intervention that targets working memory-related functions. To accomplish this goal, 80 volunteer patients with schizophrenia will be enrolled and randomized to either a cognitive remediation condition that targets working memory or a computer skills training intervention that teaches computer applications. In both conditions participants will receive computer training three times a week for 4 months. The investigators hypothesize that patients who receive the cognitive remediation intervention will demonstrate significantly greater change on neuropsychological measures of working memory and executive abilities than patients who receive the computer skills course. In addition, the investigators hypothesize that the intervention-induced cognitive change will be associated with concurrent improvements in functional capacity and psychosocial functioning in the community. A second study goal is to examine the stability of the intervention-induced changes in cognition. Cognition and psychosocial functioning will be reassessed 4 and 8 months after treatment termination to examine the stability of treatment effects and to assess whether a less intense maintenance training (once a week sessions) provides any additional benefit to participants. Lastly, this study will examine in an exploratory manner whether there are individual differences in treatment response. The Val158Met polymorphism of the COMT gene has been found to be associated with working memory and prefrontal dysfunction in schizophrenia. The study will test whether the COMT polymorphism is predictive of response to cognitive remediation.
|Schizophrenia Schizoaffective Disorder
|Behavioral: Cognitive Remediation Behavioral: Computer Skills
|Study Type:
|Study Design:
|Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Participant, Outcomes Assessor)
Primary Purpose: Treatment
|Official Title:
|Remediation of Working Memory in Schizophrenia
Resource links provided by NLM:
Genetics Home Reference related topics: schizophrenia
MedlinePlus related topics: Memory SchizophreniaU.S. FDA Resources
Further study details as provided by VA Office of Research and Development:
Primary Outcome Measures:
- Cognitive Assessment - MATRICS Consensus Cognitive Battery [ Time Frame: Post-intervention, within 2 weeks of completion of the 4 month intervention ]The Working Memory and Attention indexes of the MATRICS Consensus Cognitive Battery was used to assess near generalization of training with untrained tasks that were conceptually similar to training tasks. Each scale provide an age and gender corrected T-score. Thus, scores can range from 0-100, with a higher score indicating better performance.
Secondary Outcome Measures:
- Functional Capacity - University of California, San Diego Performance-Based Skills Assessment [ Time Frame: Post-intervention, within 2 weeks of completion of the 4 month intervention ]The UPSA is a measure of the ability to apply cognitive skills to functional tasks. The total score from this scale was used. Scores may range from 0 - 100, with higher scores being better.
|Study Start Date:
|January 2010
|Study Completion Date:
|December 2015
|Primary Completion Date:
|April 2015 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: Cognitive Remediation
A 48-session working memory focused cognitive remediation program is conducted. Training tasks have been selected from 3 software programs, PSS CogRehab, BrainTrain, and custom made N-back tasks.
Behavioral: Cognitive Remediation
This is an adaptive, computer-based cognitive training intervention. Participants will complete 3 1-hour cognitive training sessions focused on attention and working memory processes weekly for 4 months.
Placebo Comparator: Computer Skills
This is a 48-session, time matched comparison group in which participants practice keyboarding skills and the fundamentals of Microsoft Office Word, Powerpoint, and Excel programs.
Behavioral: Computer Skills
This is a computer-based course in which participants will be taught how to use Microsoft Office applications and typing skills. Participants will attend a 1-hour course three times a week four 4-months.
Information from the National Library of Medicine
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
|Ages Eligible for Study:
|18 Years to 60 Years (Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Veterans with a DSM-IV diagnosis of schizophrenia or schizoaffective disorder
- No hospitalizations in the previous 4 weeks
- No antipsychotic medication changes in the previous 4 weeks
- Age 18-60
- Does not meet DSM-IV criteria for substance dependence in the previous 6 months or substance abuse in the previous month
Exclusion Criteria:
- History of clinically significant head injury or neurological disease
- Poor comprehension of the English language
- History of diagnosis of mental retardation or pervasive developmental disorder
- Unable to give informed consent
Contacts and Locations
Information from the National Library of Medicine
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00995553
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00995553
|United States, Minnesota
|Minneapolis VA Health Care System, Minneapolis, MN
|Minneapolis, Minnesota, United States, 55417
Sponsors and Collaborators
VA Office of Research and Development
Veterans Medical Research Foundation
Minneapolis Veterans Affairs Medical Center
|Principal Investigator:
|Tasha Marie Nienow, PhD
|Minneapolis VA Health Care System, Minneapolis, MN
More Information
Additional relevant MeSH terms:
|Responsible Party:
|VA Office of Research and Development
|ClinicalTrials.gov Identifier:
|NCT00995553 History of Changes
|Other Study ID Numbers:
1I01RX000180-01 ( U.S. NIH Grant/Contract )
|First Submitted:
|October 14, 2009
|First Posted:
|October 15, 2009
|Results First Submitted:
|February 25, 2016
|Results First Posted:
|April 25, 2016
|Last Update Posted:
|April 25, 2016
|Last Verified:
|April 2016
Additional relevant MeSH terms:
Psychotic Disorders
Schizophrenia Spectrum and Other Psychotic Disorders
Mental Disorders


text:
Today's bloom is Vriesea Bromeliad (Vriesea imperialis)Bloom of the Day for June 7th, 2009:
Type of plant: Tropicals and Tender Perennials
Bloom color: Maroon (Purple-Brown), White/Near White
Bloom time of year: Mid Summer, Late Summer/Early Fall, Blooms repeatedly
Sun requirements: Sun to Partial Shade, Light Shade
Cold hardiness: Zone 10a to Zone 11
Height: 36-48 in. (90-120 cm)
Spacing: 4-6 ft. (1.2-1.8 m)
View much more information
about this plant at PlantFiles.
7 members have or want this plant for trade.
|Talk about this bloom
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The Tennessean
August 16, 201
SPRING HILL — City leaders voted unanimously Monday to quit adding fluoride to city water.
Alderman Amy Wurth asked the Board of Mayor and Aldermen for the change, saying that not all city residents may need the supplement because it appears in many more sources than it did in 1945, when fluoridation began as a way to reduce dental decay.
Twelve states and the District of Columbia require fluoride use in public water systems. In Tennessee, community water systems make that decision locally.