text:
The Music Library will close today for the summer due to continued renovation and construction work on the Humanities Building. We anticipate re-opening on August 16.
After today, Music Library materials will only be available via a paging service. Items requested through the library's online catalog will be picked up by Music Library staff each weekday and placed on the Hodges Library hold shelf (located at the main circulation desk on the second floor). In addition, graduate students and faculty may request items be delivered to them via Library Express. Though our physical location will be closed, Music Library staff will still be available by phone, email, or appointment: http://www.lib.utk.edu/music/contact.html .
Have a great summer break!


text: A Hisense technician explains the flat screen TV manufacturing process to MEC Donald Grant at the factory in Atlantis. (Duncan Alfreds, News24) RELATED ARTICLES Hisense Infinity Pure easy on wallet, eyes - review This is the best phone you've never heard of Hisense signs SA 49M green pledge Cape Town - The Western Cape is open for technology companies to do business, and it is a critical part of the provincial strategy to expand the sector.Together with Minister [Alan] Winde, in future we will make that we can cut red tape wherever we can to facilitate further export growth into Africa," said Western Cape Transport and Public Works MEC Donald Grant on Monday.Grant was speaking at the Hisense factory in Atlantis outside Cape Town as the company celebrated its first African export order for televisions.The Atlantis factory is a high-tech enterprise that has created employment for 500 people, and the company hopes to expand that to 1 200 as demand increases.On a tour of the facility, Grant and a media contingent were shown the production process and it was evident that the company is intent on consolidating market gains.Manufacturing importanceGrant said that manufacturing was important to the economy of the Western Cape in that the sector made up 17% of GDP."The important factor is that for every job created here locally, there's a ratio of three jobs that are created, both from a supplier and distribution network going forward," he added.Since entering SA in 1996, Hisense has sold around 140 000 panel TVs and 170 000 refrigerators, giving the company a 14% market share.It is on a drive to expand both in SA and Africa in general and Grant joked that he would soon be buying a new Hisense TV."Since I will be purchasing two flat screen TVs shortly, I know what I'm going to buy in future," he said.Watch MEC Donald Grant's remarks here:- Follow Duncan on Twitter Read more about: hisense | cape town | economy | technology share:

subset: commoncrawl


text:
CARLSBAD -- A busy Carlsbad intersection has reopened after a severe injury crash very early today, authorities said.
They said two people were flown to Scripps Memorial Hospital, La Jolla, after the two-vehicle collision about 2 a.m. at El Camino Real and Palomar Airport Road.
The intersection was shut down until about 8:15 a.m. for the investigation and cleanup, police said.
No further information was available.


text: My brother has a Galaxy S2 and says it comes with an app on it called "fm radio", which apparently gets a radio signal through headphones and doesn't use any data. I can't find the app though, and it's not in the app store. Am I missing it somewhere or is there a similar app available in the store which doesn't use data? Thanks!


text:
Sheep welcomes Governor to outback Qld
Queensland Governor Penny Wensley has received an outback welcome from a sheep during a visit to a remote property in the state's south-west.
Ms Wensley toured a property near Thargomindah, south-west of Longreach, yesterday, during her first visit to the Bulloo Shire.
Grazier Bridgette Hughes from Autumnvale says recent rain had made the ground wet but the Governor enjoyed the experience.
"She slid all the way into our place," she said.
"I was really nervous she was going to cancel but no she was an absolute trooper.
"She came out and we have a pet sheep - he thinks he's a jack russell dog and as soon as she pulled up, he ran to the door of her car.
"You couldn't have organised anything better as a welcoming party."
Topics: royal-and-imperial-matters, rural, people, thargomindah-4492, longreach-4730, mount-isa-4825, toowoomba-4350


text:
Nomination Criteria
Nominations for Federal Aviation Awards may be submitted by an executive agency of the federal government that owned or hired aircraft during the period from January 1, 2017 - December 31, 2017, to perform their non-military missions.
The winning programs and professionals should demonstrate the most outstanding achievements that have occurred in the past 12 months (January 2017-December 2017). Include any external assessments your agency received last year, including other awards, ARMS, surveys, or other reports such as a Government Accountability Office (GAO) review.
The Interagency Committee for Aviation Policy sets different award criteria for Program Awards and Professional Awards. Agencies should carefully consider these criteria before submitting their nominations.
Learn more about Aviation Program Award criteria.
Learn more about Aviation Professional Award criteria.


text:
IK Multimedia Ampeg SVX Plug-in Powered by Amplitube for StealthPedalProduct #701016 IK Multimedia 701016 YUC Effects Plugins https://www.esnapw.com/rses/ESnapServlet?MerchantNumberSent=63655
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The signature sound of Ampeg's SVT bass amplification in a plug-in.
IK Multimedia's Ampeg SVX plug-in is the result of a collaboration between Ampeg, a pioneer of bass amplification, and IK Multimedia, a leader in amp-modeling plug-in technology. Designed to integrate seamlessly with IK Multimedia's StealthPedal.
Mix and match between amps and cabinets of the most sought-after Ampeg gear to produce 24 amazing bass amp combinations. Plus, you'll have a complete bass pedal board with 6 fully configurable stomp effects. In addition, select among 8 classic bass effects crafted after classic Ampeg stomps and other must-have vintage gear. Add a tuner and separate direct/amped signal path for a complete software bass rig.
Ampeg SVX has over 20 bass gear emulations, including classic Ampeg bass amp models like the SVT-Classic, B-15R Portaflex "Flip Top," BA-500, and SVT-4PRO. Select from Ampeg stomps like the SPC-OCT Octaver or the SCP-OD Overdrive, or cabinets like the SVT-410H or SVT-810E, powered by AmpliTube's unique DSM (Dynamic Saturation Modeling) technology.
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text:
Item: HSAT100CLSB
The Ibanez AT100CL Andy Timmons Signature guitar looks like a pretty straight forward, simple design of a guitar. But, when you plug it in, you instantly know that this instrument has some serious Mojo happening. Perhaps it's the sum of its parts, a one piece neck with a Maple cap fretboard, Wilkenson trem, jumbo frets, awesome sounding pickups all combined into an ultimate tone machine. I was surprised how complex and organic the humbucker sounded in the bridge, it inspired me to play differently, and the neck pickup is pure single coil bliss, offering a hollowly bluesful soul to my playing.
This is more than a guitar, it's an instrument that offers inspiration to the player, and will hopefully elevate your musicianship. I can't give this instrument enough praise, rock this one today.-Scott
Do not buy a high-end Ibanez from a "Sales Engineer" sitting behind a desk. Buy from a fellow guitarist who has played the actual instrument you're looking at. I can match any of the "Big Machine's" prices, so give me a call. - Scott
HSAT100CLSB - AT100CL Andy Timmons Signature Prestige Price $2,699.99
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What is 8 plus 5


text:
BEREA -- Nate Burleson has been spinning his wheels for two weeks.
With the Browns' offense out of rhythm and the receiving corps filled with question marks -- none bigger than Josh Gordon's possible suspension -- Burleson has been unable to help, stuck to a stationary bike with a hamstring strain. He missed practice again Thursday, but ran inside, caught passes and hopes to make his Browns preseason debut Saturday night at home against the Rams.
"The first impression for me is a big deal," Burleson said. "I look at that two ways: If I go out there and I'm healthy and I do well, it's going to be a great first impression for me with the fans. But if I'm 80 percent, then that might not be the best impression.
"I want to give Cleveland what they deserve and that's Nate at 100 percent."
He's serious about wanting to play Saturday.
"The plan is this week," he said. "I tried to sneak my helmet out here and jump in and practice, but the trainers caught me. But I'm listening to the trainers.
"I wanted to play last week. The preseason for me is a big deal. I like it because it helps me with my confidence and creates momentum for me for the regular season. Hopefully I can convince these guys that I'm ready to rock."
Burleson's frustration level may be even higher when it comes to Gordon's situation. News of his failed drug test and indefinite suspension broke in May, yet Gordon and the Browns don't have resolution to his appeal.
Gordon continues to practice and play, yet could be sidelined for the entire season. If he wins the appeal, he wouldn't be suspended at all. A settlement for a different number of games could also be reached.
"I can't wait," Burleson said. "I think he's ready, too. I'm excited for whatever it is because I know Josh is ready."
The NFL hasn't said when the final ruling will be announced, but many suspensions are released on Friday afternoons and Gordon's appeal hearing ended Aug. 4.
"I think it's human nature. It's definitely weighing on him," coach Mike Pettine said. "He's like all of us, wants to know and wants to get on with it and move forward. Just kind of being in limbo for so long can be draining.
"I think he made the comment (in an Instagram post) the other day, the football field is where he feels most at home. It's important to him."
Pettine said Tuesday that Gordon could've given better effort on a few plays Monday against Washington.
"We discussed what happened in the game, and he's responded, and has had some good practices for us," Pettine said. "I just think like all of us, it's only natural that he's frustrated."
Burleson has seen Gordon trying to improve. He said Gordon was doing pushups during practice and told him he's trying to lose a little weight and get in better shape.
"He probably wouldn't tell you all that, but I'll tell you because I'm his buddy and people need to know that," Burleson said. "He's faster than everybody right now. So imagine what's going to happen when he tightens up even more. So I like where his head is at."
With roster cuts from 90 to 53 coming over the next nine days, Burleson could be a topic of conversation among the front office and coaches.
The Browns desperately need production at receiver, and Burleson has 457 catches and 39 touchdowns in an 11-year career. But he turned 33 Tuesday, only $65,000 of his one-year, $1 million contract is guaranteed and he hasn't practiced since Aug. 6.
"As a player, you've always got to be worried," he said. "That's the nature of the business. Hopefully I've put enough film on tape at practice to convince them that I'm a guy they need on this squad.
"But for me, it's just getting healthy. I would love to force the issue and go out here and do something, but I've got to be smart. The trainers are here for a reason. But, yeah, I'm confident in my own skills. I know what I'm capable of. So I'll be good."
Burleson said receivers coach Mike McDaniel has reassured him the team knows what he can do, but he has his own motivation for making it back Saturday.
"I want to play because that's what I get paid to do," Burleson said. "They brought me here for a reason and that's to add a sparkplug to this offense and make plays when the ball's thrown to me. And then after that, I'm new here. So no new guy wants to be on the sideline and I know that firsthand."
Pettine labeled Burleson's timetable as "day to day" and readily admits his concerns with the receiving corps. The coach is confident in veteran Miles Austin and slot receiver Andrew Hawkins.
"After that, I see it as really wide open," Pettine said. "There's good competition for some of those other spots."
Burleson plans to fill one of them. If Gordon is available, Burleson and Austin could form a veteran twosome at the No. 2 spot. If Gordon's out, Burleson might need to fill that role by himself.
"They cut the check for me to come out here and make plays and be a leader, and it's tough for me to do that on the sideline," Burleson said. "Hopefully I can just get out on the field, give you guys a taste of what I'm about before the season starts and then hit the ground running for 16 games."
When the season's over, Burleson will assess his future. He mentioned retiring after the season to a Detroit reporter earlier this month.
"I told myself, if I can't get open, then I'll retire. And going up against some of these young guys, getting open consistently, it gave me a lot of confidence," he said. "So when I mentioned that, it was more about me writing the perfect ending to this movie. And that's playing a tremendous season, giving Cleveland what they've always wanted in their football team, which is a team they can be proud of, and then walking off into the sunset."
Burleson was non-committal when asked if this will be his final season.
"I don't know," he said. "The plan is to go out there and be the best 33-year-old wide receiver, make some plays, put up some numbers and then make the decision from there.
"I want to do something special here, as an organization and as an individual. I want to be able to show these young guys that you can age with grace and still make plays. But first and foremost, I've got to be here to help this squad. I was born to play football. I'm committed to this organization 100 percent."
Contact Scott Petrak at 329-7253 or firstname.lastname@example.com. Like him on Facebook and follow him on Twitter @scottpetrak.
WHO: Cleveland vs. St. Louis Rams
WHAT: Third preseason game
WHEN: Saturday, 8 p.m.
WHERE: FirstEnergy Stadium
TV/RADIO: Channel 3; WKNR 850-AM, WKRK 92.3-FM, WNCX 98.5-FM


text:
Property Rights and Housing Value: The Impacts of Political Instability
Political instability may weaken investors' belief in property rights, putting the investors in fear that part of the investment may be wasted due to poor protection. As a result, the investors are unwilling to pay a premium for the security of rights when facing political uncertainty. This article attempts to test the above hypothesis using 10-year freehold and leasehold housing transaction data in Hong Kong and Singapore, where different political scenarios, comparable land lease structures as well as similar property cycles were established during the period. The conceptual model yields testable predictions about our hypotheses, and the empirical results verify the predictions. Copyright (c) 2009 American Real Estate and Urban Economics Association.
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Volume (Year): 37 (2009)
Issue (Month): 2 ()
Pages: 235-257
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text:
@JustDizle Presents: "France 9"
JustDizle writes: 'Finally, i'm excited, this mixtape is about the underground french rap scene, the songs i enjoyed in 2012, it doesn't matter what's their style, the only condition was to mix songs that were dope in my ears so here it is...'
Tracklist 01.3010 – Lamborghini Twingo
02.Riski Metekson – Paris J'arrive feat. Hifi 03:00 Amy & Ladea – Welcome to V…
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MyEssayWriting.com - Essay Writing Services.
• A one-of-a-kind resource that shows polymer clay artists how to use historic design ideas in their work• More than 30 exciting techniques and projects illustrated with clear step-by-step photos• Features the work of today's biggest names in polymer clay, including Donna Kato, Pier Voulkos, Kathleen Dustin, Ford + Forlano, and KLEWThousands of crafters have discovered that polymer clay is versatile, easy to use, and just plain fun. Now they can use this exciting medium to create remarkable new work inspired by the decorative arts of the past. Polymer Clay Creative Traditions lets both beginners and experienced artisans draw inspiration form painting and drawing, ethnic carving, quilting, ceramics, sculpture, glass, metalwork, and more.
Thorough 300 stunning photographs and fascinating text, author Judy Belcher reveals how these influences can be expressed in polymer clay. Introduction on the history and handling, plus tips and techniques throughout the book, make Polymer Clay Creative Traditions an invaluable guide to creating works of art that blend a great material of today with the greatest design ideas of yesterday.


text:
MyShingle Profile: Jay Fleischman, New York Bankruptcy Lawyer
The MyShingle profiles are an experimental feature here at MyShingle – to offer some insight into the careers of practicing solo and small firm attorneys, with questions on how they got their start to what gets them going in the morning. My thanks to Jay Fleischman and Walter James (next post) for serving as guinea pigs for this feature.So without further, ado, meet Jay S. Fleischman – New York Bankruptcy Lawyer.
Jay S. Fleischman is a New York bankruptcy and consumer protection and a lawyer who helps other lawyers market, manage and grow their practices. He is the New York co-chair of the National Association of Consumer Bankruptcy Attorneys, a co-founder and the current President of the Bankruptcy Law Network, and a member of the National Association of Consumer Advocates. He lives in Brooklyn, NY with his wife, son and dog."
1. What kind of law do you practice?
I am a consumer protection lawyer concentrating in consumer bankruptcy, debt collection abuse, and credit reporting errors. I represent consumers only.
I began my firm on December 19, 2005 after giving notice one day before raises and bonuses were announced at my former employer. My timing was deliberate, and based on my fear of: (a) if my raise and bonus were too good then I'd find it more difficult to leave; and (b) if my raise and bonus were below my expectations then I might suffer a crisis of confidence.
My firm has been as large as 12 people, and is now comprised solely of me. I employ a large network of virtual assistants and of-counsel attorneys who all come together to work on matters as needed. This allows me to expand and contract as needed without worrying about bloated overhead that plagues so many lawyers.
My biggest challenge was in learning how to effectively market and manage my practice. Lawyers suffer from a knowledge gap when it comes to marketing and managing a successful business, so looking to other lawyers and law firms proved fruitless. I addressed the challenge by looking outside of the legal industry and modeling my practice on successful business principles.
5. Who was your first client – and how did he or she find you?
My first client was a woman who was experiencing bill problems. She was a single mom with a young daughter, no insurance, and extreme debt due to her daughter's chronic illness. She found me from a print ad in a local newspaper, and called during the worst snowstorm New York City had experienced in years (Monday, January 8, 1996 was the day I was in the office, and the day everyone else was home or playing out in the 17″ of snow we got that day). I was convinced someone would call, and she did – but she chose me because (shock) I was the only one at work to answer her questions.
I have been exceptionally lucky to have found an entire network of mentors in the world of consumer bankruptcy. Not only the attorney members of the National Association of Consumer Bankruptcy Attorneys, but also those involved with me in Bankruptcy Law Network. Without these incredibly helpful and intelligent lawyers I would never have attained my current level of knowledge.
I am blessed to be practicing in a field that allows me to see people at their worst and effect a real change in their lives. Money makes the world go around, and helping people get back on their financial feet is very rewarding.
8. Share an "aha" moment of your practice – a time when you realized that you were doing exactly what you were supposed to be doing.
My clients were a husband and wife with two young children. One spouse had experienced significant health problems that required the family to live on one income for a significant period of time. By the time they had recovered, the house was in foreclosure and the car was edging towards repossession. Using the consumer protection and bankruptcy laws I was able to help them keep their home and car, get out from under a mountain of debt, and resume their productive lives. They still live in that home – 9 years later – and are doing very well.
I'm an only child of working-class parents, neither of whom had the benefit of a college education. My father worked his tail off, putting in 14 hours days for years just to put food on the table. Giving me a better life was all my parents ever wanted, and I watched them teeter on the brink of economic collapse for years. I know what it's like to be in debt, and to want more for the future. That knowledge informs my entire practice, and the way I work with clients.
Not everyone is a good fit for bankruptcy, and people are shocked whenI tell them that I turn away 60% of my clients. Some people need some guidance, others should investigate other options rather than going into bankruptcy. My job is to help people, not to force a square peg into a round hole.
Finally, I take a holistic approach to bankruptcy and consumer protection. The end of the case is the beginning of the relationship between the client and my office. My work includes helping to restorecredit, build credit scores, and provide long-term budgeting advice. A client is not successful until they are financial stable, and it's my job to help attain that goal.
My practice began as solely consumer bankruptcy, and has evolved to encompass all facets of consumer protection law. In the future, that evolution will surely continue as the laws change to meet the growing needs of the consumer.
Lawyers suffer from a knowledge gap when it comes to marketing and managing a successful business, so looking to other lawyers and law firms proved fruitless. That's why I have taken up the torch and created the Blizzard System of marketing, as well as my blog at www.BKPracticePro.com
Learning the law – any field of the law at all – is not rocket science. It requires careful and thoughtful study, a willingness to seek out and follow mentors, and to continue the process of learning through your entire life. Always remember who your client is, and what keeps them awake at night. Your service must address those fears and anxieties, and offer solutions that fit those needs. If you do that, you will succeed.
But if you insist on imposing your solutions in spite of the client's true needs and wants then you will end up frustrated and a failure.


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(NONE) Chairman John P Jr Hickey buys 2,500 Shares
Posted by: insider (IP Logged)
Date: June 6, 2012 04:23PM
Chairman of (NONE) John P Jr Hickey buys 2,500 shares of NONE on 06/05/2012 at an average price of $0.26 a share.
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text:
Malva Species, White Mallow, Musk Mallow
Malva moschata f. alba
|Malvaceae (mal-VAY-see-ee) (Info)
|Malva (MAL-vuh) (Info)
|moschata f. alba
Foliage Color:
Bloom Characteristics:
This plant is attractive to bees, butterflies and/or birds
Flowers are fragrant
Water Requirements:
Drought-tolerant; suitable for xeriscaping
Average Water Needs; Water regularly; do not overwater
Where to Grow:
24-36 in. (60-90 cm)
18-24 in. (45-60 cm)
USDA Zone 3a: to -39.9 �C (-40 �F)
USDA Zone 3b: to -37.2 �C (-35 �F)
USDA Zone 4a: to -34.4 �C (-30 �F)
USDA Zone 4b: to -31.6 �C (-25 �F)
USDA Zone 5a: to -28.8 �C (-20 �F)
USDA Zone 5b: to -26.1 �C (-15 �F)
USDA Zone 6a: to -23.3 �C (-10 �F)
USDA Zone 6b: to -20.5 �C (-5 �F)
USDA Zone 7a: to -17.7 �C (0 �F)
USDA Zone 7b: to -14.9 �C (5 �F)
USDA Zone 8a: to -12.2 �C (10 �F)
USDA Zone 8b: to -9.4 �C (15 �F)
Sun Exposure:
Full Sun
Sun to Partial Shade
Bloom Color:
White/Near White
Bloom Time:
Late Spring/Early Summer
Mid Summer
Late Summer/Early Fall
Blooms repeatedly
Other details:
Soil pH requirements:
6.6 to 7.5 (neutral)
Patent Information:
Propagation Methods:
From seed; direct sow outdoors in fall
From seed; winter sow in vented containers, coldframe or unheated greenhouse
From seed; stratify if sowing indoors
From seed; sow indoors before last frost
From seed; direct sow after last frost
From seed; germinate in a damp paper towel
Self-sows freely; deadhead if you do not want volunteer seedlings next season
Seed Collecting:
Allow pods to dry on plant; break open to collect seeds
This plant has been said to grow in the following regions:
Fairfield, California
Littleton, Colorado
Fishers, Indiana
Massena, New York
Lima, Ohio
Langley, Washington
Port Orchard, Washington
Vancouver, Washington
Porterfield, Wisconsinshow all
Gardeners' Notes:
On Jun 19, 2016, daisygirl_01 from Port Orchard, WA wrote:
A very happy plant in our mild Pacific NW climate. Mine grow best in full sun and self sow each year producing a multitude of seedlings (many that I remove, because it seeds so profusely). I also have volunteers in a shady location which seem to fair well, but don't bloom as profusely as those in 6+ hours of sun. The plants I have are an Alba - which were all originally volunteers growing on the border of our heavily wooded property near a grassy, very sunny location with poor, rocky, but somewhat damp soil. I've enjoyed them as an addition to our flower garden for 5+ years now and hope they continue. I use the young tender greens in salads, but have yet to nosh on the fragrant flowers or their seeds. I couldn't imagine the garden without them now.
On Oct 17, 2003, Legit from Porterfield, WI (Zone 4b) wrote:
This plant is one of the staples of my Cottage Garden. It is carefree and requires no maintenance. It reseeds itself but not as freely as the pink variety. Excellent, but not for the person who can't handle volunteers! Legit
On Feb 2, 2003, Crimson from Clarksville, TN (Zone 6b) wrote:
Did not do well in part shade... grew spindley and floppy.
On Nov 24, 2002, Weezingreens from Seward, AK (Zone 3b) wrote:
Malva moschata is a very successful perennial in our northern climate. I first started my M. moschata alba from seed in the spring of 2000, and by 2002 it flowered profusely and reached a height of about 2 ft. Sometimes the blooms take on a pinkish tinge that, I think, can be attributed to our cooler weather. It self-seeded in the bed, as well, & one of its volunteers produced blooms the first year.


text:
Dear Diary,
Lame, Lame, Lame weekend. Friday got really sick and ended up in the Emergency room and Diary that ER Dr. was the handsomest (is that a word?) Dr. I have ever seen. He walked in with his royal blue eyes, black hair, and asked me what was wrong annnnnd I forgot. So Diary if you ever need to go to the ER I recommend Fairview Southdale, I think that's where I was…(shoutout to Dr.
Handsome Adams, RN Bob who were awesome and my friend Nicki who came to take care of me). Left with some pain killers that's about it so gotta go back to the Dr…boo. Saturday I came to work and was in bed by 8:30 being an adult is not fun at all. Sunday I watched some of the Viking game while I did some work in the community room of the apartment. Some random kids were playing hide and seek. I was sitting at this small table in the corner when all of a sudden some random 7 yr old (he looked 7) dives under my table without hesitation. I took a picture of course…basically the highlight of my weekend.
Hey there little buddy.
After I got out of the hospital I slept allllllll day on Saturday, about 1pm I felt little paws walking on me, I opened my eyes to see this…Now usually when I grab my phone to put it in their face to take a picture they turn their heads or move away…nope. they stayyyyed right there, ready to get up.


text: I just won a Rodenstock 80/4 APO enlarging lens off ebay and realized it is not the N version. Stupid me. I paid $200, but can return it if I wish. Are there major differences between the N and non N versions of this lens? I believe N means its multi-coated? I currently have a Schneider Componon-S 80/4 and wanted to compare to the Rodenstock 80/4 APO N. I do black and white work only. Thanks. Brian


text:
An Efficacy, Safety, and Tolerability Study of Canagliflozin in Patients With Type 2 Diabetes Mellitus Who Have Moderate Renal Impairment
This study has been completed.
Janssen Research & Development, LLC
ClinicalTrials.gov Identifier:
First Posted: February 8, 2010
Last Update Posted: August 14, 2013
Information provided by (Responsible Party):
Janssen Research & Development, LLC
- Full Text View
- Tabular View
- Study Results
- Disclaimer
- How to Read a Study Record
Detailed Description:
The purpose of this study is to evaluate the efficacy and safety of 2 different doses of canagliflozin compared with placebo in patients with type 2 diabetes mellitus who have reduced kidney function.
|Diabetes Mellitus, Type 2 Renal Insufficiency
|Drug: Canagliflozin Drug: Placebo
|Phase 3
|Study Type:
|Study Design:
|Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
|Official Title:
|A Randomized, Double-Blind, Placebo-Controlled, 3-Arm, Parallel-Group, 26-Week, Multicenter Study With a 26-Week Extension, to Evaluate the Efficacy, Safety and Tolerability of Canagliflozin in the Treatment of Subjects With Type 2 Diabetes Mellitus Who Have Moderate Renal Impairment
Resource links provided by NLM:
Genetics Home Reference related topics: type 2 diabetes
Drug Information available for: CanagliflozinU.S. FDA Resources
Further study details as provided by Janssen Research & Development, LLC:
Primary Outcome Measures:
- Change in HbA1c From Baseline to Week 26 [ Time Frame: Day 1 (Baseline) and Week 26 ]The table below shows the least-squares (LS) mean change in HbA1c from Baseline to Week 26 for each treatment group. The statistical analyses show the treatment differences (ie, each canagliflozin group minus placebo) in the LS mean change.
Secondary Outcome Measures:
- Percentage of Patients With HbA1c <7% at Week 26 [ Time Frame: Week 26 ]The table below shows the percentage of patients with HbA1c <7% at Week 26 in each treatment group. The statistical analyses show the treatment differences (ie, each canagliflozin group minus placebo) in the percentage.
- Change in Fasting Plasma Glucose (FPG) From Baseline to Week 26 [ Time Frame: Day 1 (Baseline) and Week 26 ]The table below shows the least-squares (LS) mean change in FPG from Baseline to Week 26 for each treatment group. The statistical analyses show the treatment differences (ie, each canagliflozin group minus placebo) in the LS mean change.
|Study Start Date:
|June 2010
|Study Completion Date:
|August 2012
|Primary Completion Date:
|December 2011 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: Canagliflozin 100 mg
Each patient will receive 100 mg of canagliflozin once daily for 52 weeks.
Drug: Canagliflozin
One 100 mg or 300 mg over-encapsulated tablet orally (by mouth) once daily for 52 weeks in addition to the patient's AHA regimen used in accordance with local prescribing information
Experimental: Canagliflozin 300 mg
Each patient will receive 300 mg of canagliflozin once daily for 52 weeks.
Drug: Canagliflozin
One 100 mg or 300 mg over-encapsulated tablet orally (by mouth) once daily for 52 weeks in addition to the patient's AHA regimen used in accordance with local prescribing information
Placebo Comparator: Placebo
Each patient will receive matching placebo once daily for 52 weeks.
Drug: Placebo
One matching placebo capsule orally once daily for 52 weeks in addition to the patient's AHA regimen used in accordance with local prescribing information
Detailed Description:
This is a randomized (study drug assigned by chance), double blind (neither the patient or the study doctor will know the name of the assigned treatment), parallel-group, 3-arm (patients will be assigned to 1 of 3 treatment groups) multicenter study to determine the efficacy, safety, and tolerability of 2 different doses of canagliflozin (100 mg and 300 mg) compared to placebo (a pill that looks like all the other treatments but has no real medicine) in patients with type 2 diabetes mellitus (T2DM) who have renal impairment (reduced kidney function) and who are not achieving an adequate response from current therapy to control their diabetes. Canagliflozin (also referred to as JNJ-28431754) is a drug that is being tested to see if it may be useful in treating patients diagnosed with T2DM. Approximately 240 patients will participate in the study for approximately 63 to 72 weeks, depending on the length of the pretreatment phase. The study will consist of a pretreatment phase, a 52 week double blind treatment phase, and a posttreatment phase. During the pretreatment phase, screening evaluations will be performed to see if patients meet the entry criteria for the study. In addition, routine clinical procedures will be performed (physical examination, vital signs measurements, and an electrocardiogram [ECG]), a blood and urine sample will be collected for routine clinical laboratory tests, and all antihyperglycemic therapy taken by patients will be reviewed. Patients who meet entrance criteria for the study and who currently take a stable antihyperglycemic agent (AHA) regimen according to the local prescribing information will be eligible for inclusion in the study. Patients who meet entrance criteria for the study but who are not taking a stable AHA regimen according to the local prescribing information will enter an AHA adjustment period that may last for up to 12 weeks. Patients will receive once daily treatment with study drug in addition to their current stable diabetes regimen (eg, diet, exercise, and medication therapy). Patients will continue to take their assigned treatment for 52 weeks (includes a 26-week core double-blind treatment period and a 26-week extension double-blind treatment period). During the study, if a patient's blood sugar remains high despite treatment with study drug in combination with their other antidiabetic agents, the study physician will modify the patient's treatment. If patients take insulin and experience low blood sugar (hypoglycemia), the dose of insulin may be modified. During the study, patients will be monitored for safety by review of adverse events, results from safety laboratory tests (including chemistry, hematology, and urinalysis), ECGs, vital signs measurements, body weight, physical examinations, self-monitored blood glucose, and collection of potential hypoglycemic episodes reported by patients on diary cards. The safety of patients in this study will also be monitored by a company internal Medical Safety Review Committee (MSRC). An Independent Data Monitoring Committee (IDMC) will evaluate cardiovascular (CV) events that are reported across the entire clinical development program for canagliflozin. Patients who complete the Week 52 visit or who discontinue treatment early and are withdrawn from the study will have end-of-study evaluations performed and a follow-up telephone interview conducted by study personnel approximately 30 days (but no more than 42 days) after the last dose of study drug to collect any serious adverse events that occurred since their last study visit. The primary outcome measures in the study are to assess the effect of canagliflozin relative to placebo on hemoglobin A1c (HbA1c, a blood test used to measure the control of diabetes) after 26 weeks of treatment and to assess the safety and tolerability of canagliflozin from time of signed informed consent to study end (includes up to 30 days following the last dose of study drug). All patients will take a single-blind placebo capsule once daily for 2 weeks before randomization to double-blind study drug. After randomization, patients will take one capsule of canagliflozin (either 100 mg or 300 mg) or matching placebo orally (by mouth) with liquid once daily for 52 weeks before the first meal each day except on days when fasting or pharmacokinetic blood samples are collected in which case study drug will be taken after the visit immediately before the patient's next meal.
Information from the National Library of Medicine
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
|Ages Eligible for Study:
|25 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Patients with T2DM not on an AHA or on any AHA in monotherapy or combination therapy (including oral or non oral agents)
- Patients with reduced kidney function
Exclusion Criteria:
- History of diabetic ketoacidosis, type 1 diabetes mellitus (T1DM), pancreas or beta cell transplantation, or diabetes secondary to pancreatitis or pancreatectomy
- Have proliferative diabetic retinopathy for which treatment is planned during the course of the study
- Kidney disease that required treatment with immunosuppressive therapy, history of dialysis or kidney transplant, presence of nephrotic syndrome (eg, severe proteinuria with hypoalbuminemia and/or edema), or inflammatory kidney disease
- Receiving anti hypertensive or anti-hyperlipidemic therapy not on a stable regimen
- History of a severe hypoglycemic episode within 6 months before screening
Contacts and Locations
Hide Study Locations
Information from the National Library of Medicine
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01064414
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01064414
Hide Study Locations
|United States, California
|Concord, California, United States
|Fountain Valley, California, United States
|San Diego, California, United States
|United States, Colorado
|Denver, Colorado, United States
|United States, Florida
|Pembroke Pines, Florida, United States
|Tampa, Florida, United States
|West Palm Beach, Florida, United States
|United States, Georgia
|Augusta, Georgia, United States
|United States, Idaho
|Nampa, Idaho, United States
|United States, Louisiana
|Baton Rouge, Louisiana, United States
|United States, Mississippi
|Jackson, Mississippi, United States
|Picayune, Mississippi, United States
|United States, Missouri
|Chesterfield, Missouri, United States
|United States, Nevada
|Las Vegas, Nevada, United States
|United States, New Mexico
|Albuquerque, New Mexico, United States
|United States, North Carolina
|Durham, North Carolina, United States
|United States, Ohio
|Canal Fulton, Ohio, United States
|Cincinnati, Ohio, United States
|Columbus, Ohio, United States
|Zanesville, Ohio, United States
|United States, Oklahoma
|Oklahoma City, Oklahoma, United States
|United States, Pennsylvania
|Meridian, Pennsylvania, United States
|Pittsburgh, Pennsylvania, United States
|United States, South Carolina
|North Charleston, South Carolina, United States
|United States, Utah
|Salt Lake City, Utah, United States
|United States, Virginia
|Fairfax, Virginia, United States
|Camperdown, Australia
|Gosford, Australia
|Parkville, Australia
|Reservoir, Australia
|Aalst, Belgium
|Bonheiden, Belgium
|Brussels, Belgium
|Liège, Belgium
|Sint-Niklaas, Belgium
|Turnhout, Belgium
|Sao Paulo, Brazil
|São Paulo, Brazil
|Canada, British Columbia
|Vancouver, British Columbia, Canada
|Victoria, British Columbia, Canada
|Canada, Nova Scotia
|Antigonish, Nova Scotia, Canada
|Sydney, Nova Scotia, Canada
|Canada, Ontario
|Hamilton, Ontario, Canada
|London, Ontario, Canada
|Smiths Falls, Ontario, Canada
|Thornhill, Ontario, Canada
|Canada, Quebec
|Montreal, Quebec, Canada
|Calgary, Canada
|Corbeil Essonnes, France
|La Rochelle Cedex 1 Poitou-Cha, France
|Le Creusot, France
|Nantes N/A, France
|Pierre Benite, France
|Vandoeuvre Les Nancy, France
|Venissieux, France
|Dormagen, Germany
|Dortmund, Germany
|Dresden, Germany
|Einbeck, Germany
|Freiburg, Germany
|Kassel, Germany
|München, Germany
|Schkeuditz, Germany
|Würzburg, Germany
|Aurangabad, India
|Madurai, India
|Pune, India
|Korea, Republic of
|Seognam-Si, Kyungki-Do, Korea, Republic of
|Seoul, Korea, Republic of
|Daugavpils, Latvia
|Ogre, Latvia
|Riga, Latvia
|Jalan Cheras N/A, Malaysia
|Kajang, Malaysia
|Kuala Lumpur N/A, Malaysia
|Pulau Pinang, Malaysia
|Aguascalientes, Mexico
|Culiacan, Mexico
|Morelia, Mexico
|Zapopan, Mexico
|New Zealand
|Auckland, New Zealand
|Christchurch, New Zealand
|Dunedin Nz, New Zealand
|Nz, New Zealand
|Lask, Poland
|Lublin, Poland
|Warszawa, Poland
|Bucharest, Romania
|Targoviste, Romania
|Russian Federation
|Chelyabinsk, Russian Federation
|Kirov, Russian Federation
|Kursk, Russian Federation
|Moscow, Russian Federation
|Nizhny Novgorod, Russian Federation
|Petrozavodsk, Russian Federation
|Rostov-On-Don, Russian Federation
|Saint Petersburg, Russian Federation
|St Petersburg, Russian Federation
|Yaroslavl, Russian Federation
|South Africa
|Parow, Cape Town, South Africa
|Pretoria, South Africa
|Somerset West, South Africa
|Barcelona, Spain
|Ciudad Real, Spain
|Madrid N/A, Spain
|Madrid, Spain
|San Sebastian De Los Reyes, Spain
|Santa Cruz De Tenerife, Spain
|Valencia, Spain
Sponsors and Collaborators
Janssen Research & Development, LLC
|Study Director:
|Janssen Research & Development, LLC C. Clinical Trial
|Janssen Research & Development, LLC
More Information
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Keywords provided by Janssen Research & Development, LLC:
Additional relevant MeSH terms:
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Watts NB, Bilezikian JP, Usiskin K, Edwards R, Desai M, Law G, Meininger G. Effects of Canagliflozin on Fracture Risk in Patients With Type 2 Diabetes Mellitus. J Clin Endocrinol Metab. 2016 Jan;101(1):157-66. doi: 10.1210/jc.2015-3167. Epub 2015 Nov 18.
Weir MR, Kline I, Xie J, Edwards R, Usiskin K. Effect of canagliflozin on serum electrolytes in patients with type 2 diabetes in relation to estimated glomerular filtration rate (eGFR). Curr Med Res Opin. 2014 Sep;30(9):1759-68. doi: 10.1185/03007995.2014.919907. Epub 2014 May 22.
Nyirjesy P, Sobel JD, Fung A, Mayer C, Capuano G, Ways K, Usiskin K. Genital mycotic infections with canagliflozin, a sodium glucose co-transporter 2 inhibitor, in patients with type 2 diabetes mellitus: a pooled analysis of clinical studies. Curr Med Res Opin. 2014 Jun;30(6):1109-19. doi: 10.1185/03007995.2014.890925. Epub 2014 Feb 21.
|Responsible Party:
|Janssen Research & Development, LLC
|ClinicalTrials.gov Identifier:
|NCT01064414 History of Changes
|Other Study ID Numbers:
28431754DIA3004 ( Other Identifier: Janssen Research & Development, LLC )
|First Submitted:
|February 4, 2010
|First Posted:
|February 8, 2010
|Results First Submitted:
|April 2, 2013
|Results First Posted:
|May 27, 2013
|Last Update Posted:
|August 14, 2013
|Last Verified:
|August 2013
Keywords provided by Janssen Research & Development, LLC:
Sodium-Glucose Transporter 2
hemoglobin A1c protein, Blood Glucose
reduced kidney function, Type 2 diabetes mellitus
Additional relevant MeSH terms:
Diabetes Mellitus
Diabetes Mellitus, Type 2
Renal Insufficiency
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases
Kidney Diseases
Urologic Diseases
Hypoglycemic Agents
Physiological Effects of Drugs


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West Palm Beach (Fla.) Dwyer quarterback Jacoby Brissett racked up numerous offers throughout the spring after leading the Panthers to a state title in 2009. The 6-foot-5, 225-pound Rivals250 prospect threw for over 2,200 yards and added another 400-plus with his feet, showing colleges that he could be a dual-threat if needed.
Brissett is also a star basketball player who is being heavily recruited in that sport as well. This summer, he spent much of his time on the AAU circuit and sort of put recruiting on the back burner a bit. In fact, he admits he stepped back from the process, especially interviews, going so far as turning off his phone. He spoke at length on Monday afternoon, though.
"I've been kind of like trying to enjoy my last summer," Brissett said. "I kind of turned my phone off to get away from all that. I emailed back and forth with coaches a lot, but I just wanted to have fun and not have to think about recruiting too much. I've pretty much been keeping in contact with all the coaches. I try to stay in contact and they email me a lot."
Article Continues Below
Despite taking a step back, Brissett says he has been able to pare down his college choices a bit. In fact, he says seven programs remain in the running for his services.
"I've narrowed it down a little bit, yeah," he said. "Notre Dame, North Carolina, Wisconsin, Florida State, USF, LSU and South Carolina - those are the ones that I'm still looking at.
"I haven't set up any official visits yet. I was thinking about where I wanted to go today, but I didn't have that much time to do anything about it. I'm not sure exactly where I'm going yet. I kind of want to go see some things and see some places but I don't know yet."
Though many of those programs have other quarterback commits, Brissett says that is not something that is factoring in his decision.
"I follow recruiting somewhat but not too much," he said. "Pretty much every school that I listed, I'm No. 1 on their list. They probably have other commitments (at quarterback) but they're still recruiting me. It doesn't affect me if they have other QB's committed."
The big quarterback had a chance to take in several college campuses this summer, but says he did not truly get to experience each one.
"I visited North Carolina, Tennessee, Georgia, Alabama, Wisconsin, Florida State, USF and Louisville this summer," Brissett said. "Since it was the summer, there wasn't much really going on at any of the places so it was hard to really get a read on the schools. All the campuses were nice. The people that were there were pretty much cool at all the places."
With the possibility of playing basketball or football in college, Brissett is still wrestling with the decision on which sport to focus.
"It's still up in the air," he said. "I kind of want to do both my first year to check and see how it is. It all depends on how I come in my freshman year and how I feel, if I'm going to make an impact on the team.
"I've talked to the basketball coaches and the football coaches and they told me that, anytime I had time off, I could go to the other sport. When I'm in one sport then I'm just concentrating on that one, though. It could be hard as a QB, but we'll see."
Though he spent much of the summer on the hardwood, it does not mean that Brissett is not ready for the football season.
"Every time I came back from a (basketball) trip, I came to football and worked out," he said. "I've been doing that as much as possible. Throughout the month of June I was working out two times a day."
Dwyer is coming off a state championship but Brissett loses such receivers as Matt Elam, Gerald Christian and Robert Clark, who all signed with Florida. Though the team returns the country's top tight end in Nick O'Leary, the receiving corps is still a question mark.
"It's been a bit of a concern all this time, since we lost those guys from last year," Brissett said. "I think we have a lot of guys that are coming and stepping up and ready to make plays that want to play."
Despite the presence of Brissett, O'Leary and four-star defensive end Curt Maggitt, many people are doubting whether Dwyer can repeat their state title run. Brissett says it serves as motivation.
"I honestly don't think there's that much pressure," he said. "Everybody knows that we lost a lot of talent so they're expecting us to lose and everybody wants to beat us since we're the state champions. Our thought it that we are just going to take things one game at a time and win every game from start to finish and be state champs again.
"Our motto out here is, 'Win every game, win every snap.' We want to go out and prove everybody wrong."
Brissett and his Dwyer teammates play a tough schedule, opening up the season in the Herbstreit Classic at Ohio State against Cleveland (Ohio) Glenville on Sep. 6.


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Courage For Today Ministries
Affordable Online Christian Life Coaching
November 4, 2017 by Mike Weaver Leave a Comment
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"It doesn't matter how messy life has become; it's never too late for God to do a miracle. It's never too late for God to restore your family, your health, your mind. It's never too late for him to put your life back together." —Louie Giglio


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My Nonprofit Reviews
SgtMaj of Marines
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Review for Freedom Alliance, Dulles, VA, USA
Freedom Alliance has been helping my Marines and family for years now. With the ever shortage of funds and resources for our service members, Freedom Alliance is an amazing organization. Thank you for all that you do for our Marines and their families. Semper Fidelis!
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text:
Business for Sale Summary
Semi-Absentee Run Hair Salon and Barbershop on UES - 26355Business Type: best deals!,must sell/drastic price reduction!,absentee business,seller financing available,beauty salon/ barber shop
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Financial Information (non-confidential)
|General Information
|Asking Price
|Down Payment
|Gross Revenues
|Lease Remaining
|Register Free to View
|Owner's Cash Flow
|Number of FT Employees
|Register Free to View
$60,000 Down and seller will finance $40,000 over 12 months at 6%
Business Description
This 2-year-old semi-absentee run hair salon and barbershop is located on Manhattan's Upper East Side. 70% of the customers are women and 30% men. Rent is only $2,420/month for 300 square feet just a few steps up from street level and right around the corner from a main avenue with plenty of foot traffic. The owner has been disposing of all of his hair salons and barbershops to focus his attention on an entirely different field. He will sign a non-compete. Open Tu-Sa 10am-8pm, this salon offers quality and experienced cutting, coloring, conditioning, threading and eyelash extension services provided by 5 stylists and 1 full-time assistant. The salon is currently averaging revenues of $3,000/week with 4 styling stations. A new hands-on owner could double that and make at least $100,000/year. Please become a premium member at www.vestedbb.com to receive the name and address of this restaurant to do a discreet walk by, then email or call Senior Vested Business Broker Jay Goldman (email@example.com or 1-646-670-1961) for an appointment to take a full tour and speak with the seller.
Disclaimer: The financial information in this business listing has been provided by the Seller. Vested Business Brokers, Ltd. (VBB) has not independently verified this information. Therefore, we make no claims as to the accuracy of this financial summary. Vested recommends that you consult with an accountant, attorney and/or other professionals to represent and assist you in any business transaction. One of our associate brokers will arrange a meeting between you, your representatives, and the Seller, but they are not authorized to make any representations or warranties on behalf of the seller or VBB. You agree to hold Vested Business Brokers and its associated brokers harmless for any misrepresentations made by seller.
- Asking Price: $195,000
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- Absentee business
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text:
Xavi returns to full training after injury
MADRID, April 21 (Reuters) - Barcelona and Spain midfielder Xavi completed a full training session with the squad on Friday, as he continued his return from a serious knee injury.
'If everything goes as it has been doing and I don't suffer any setbacks I will definitely be going to the World Cup,' Xavi was quoted as saying on the Marca website.
'I hope to be able to play in Barcelona's last two or three league games, and if they reach the Champions League final I also hope to be able to help them in Paris.
'This Sunday against Sevilla is a bit soon but next week maybe I will get a run out if the coach agrees.'
Xavi has been out of action for four months and is battling to reach full fitness in time for the World Cup finals in Germany, which begin in June.
He tore the cruciate ligament in his right knee during training at the beginning of December.
Barcelona top the Primera Liga by 11 points with five games to go, and could take the title with a victory away to Sevilla if second-placed Valencia fail to beat Athletic Bilbao.


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Japanese brand Challenger worked with Hash Browns on two hats for Summer 2010. The hats come with a short brim and are entirely made from canvas. Also they come with a patch all-over decoration, taking away a bit of the otherwise classic shape and appeal. The hats are now available from Bench Tokyo.
More detailed images of the hats follow after the jump.


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Have you ever received a gourmet basket with your favorite wine and other yummy goodies?
A sophisticated gift of Champaign with caviar or a humble bottle of Chardonnay paired with old French cheeses?
If yes, then you probably know what an awesome idea it is!
No matter what the occasion, learn here how to make your friends happy with this great selection of wine - and don't forget to find among the best wine country gift baskets your own wonderful gift!
1. Merlot …
Merlot is a soft and fruity dry red wine, which originated in the French region of Bordeaux. It is famous for its deep aromas of black cherry, currant, and green olive along with mint and tobacco tones. This wine is the most delicious when served slightly below room temperature to accompany simply prepared dishes, such as grilled chicken or a roast leg of lamb.
2. Pinot Noir …
Pinot Noir is chiefly associated with the Burgundy region of France. Joel Fleischman of Vanity Fair describes Pinot Noir as "the most romantic of wines, with so voluptuous a perfume, so sweet an edge, and so powerful a punch that, like falling in love, they make the blood run hot and the soul wax embarrassingly poetic." Master Sommelier Madeline Triffon calls Pinot "sex in a glass". This wine is one of the most popular in the world, despite the fact that it comes from a sort of grapes, which is difficult to cultivate and ferment into wine. Traditional types of Pinot Noir are famous for their fleshy, 'countryside' aroma, while modern forms have a lighter, fruiter flavour. It pairs well with lamb, pheasant, and duck, although the best match for this wine is grilled salmon topped with creamy mushrooms.
3. Riesling …
Riesling came from the river valleys of Germany. Unlike other wines, it rarely blends and, thus, remains a pure dry white wine with clear aromas of tropical fruit, flowers, and minerals. It has a sweet taste with notable acidity, which makes it one of a few wines that can stand up to the dishes of Chinese and Thai cuisines. Riesling can serve as a good balance to salty foods and to the light, delicate flavour of trout fried in butter. As with other white wines, dry Riesling is usually served at 52°F.2
4. Chablis …
Chablis is a clean and vibrant French white wine with a crisp dry flavour and a prominent mixture of sweetness and acidity. It is definitely a gourmet wine, which requires special food occasions. Chablis is the classic oyster companion and it also perfectly compliments expensive fish dishes of fine cuisine.
5. Cabernet Sauvignon …
Cabernet Sauvignon originally from Bordeaux, France, it is a popular dry wine fermented from the "king of red wine grapes". In the mid-60s, it began to emerge as the most popular red wine in the United States. It has a rich and sophisticated aroma of cedar, berries, and chocolate, which varies depending on the region and age. This wines combines perfectly with pastas, meats, aged cheeses, and dark chocolate. Cabernet Sauvignon even has a proven medicinal qualities - it reduces the risk factors of Alzheimer's disease!2
Which ever wine from the above ones you choose, the person you want to get a gift for will truly appreciate your great sophisticated taste in fine wines!
Other Wonderful Gift Ideas:
Gifts for Women:
Gifts for Men:
Party Gifts:
Photo Credit: slack12


text: Decided to start a new thread on this idea, that personal style comes from an habitual way of dancing. And then, if one is dancing habitually, can they be "in the moment", whatever that means? We recognize the individual style of many well known dancers, because they have certain movements that they regularly do. I guess you could call that a habit.


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Kinds in Love 2016 HDRip XviD AC3-EVOAug 29
Plot: Set against the backdrop of an underground, bohemian London, Kids In Love offers a new take on the traditional coming of age story. Drifting through his gap year with internships and travel plans, Jack (Will Poulter) has always suspected there was more to life than this. A chance encounter with the beautiful and ethereal Evelyn (Alma Jodorowsky) and her friends, including free spirited Viola (Cara Delevingne), swerves his life radically off course. She is like no one he's ever met before, and he quickly becomes caught up in a whirlwind of all-day parties and wild nights in London's hidden dives with her charismatic friends. Giving up everything to follow Evelyn and her hedonistic lifestyle, it takes Jack a while to realise what he's leaving behind, that love isn't a game you want to lose and that these people might not be the kindred spirits he first thought.
Genre: Drama
IMDB Rating: 6.0/10 from 37 users
Directed by: Chris Foggin
Starring: Will Poulter, Alma Jodorowsky, Sebastian De Souza
Release Name: Big.Bad.2016.HDRip.XviD.AC3-EVO
Size: 1.37 GB
Video: Avi | 720×304 | 1800 kbps
Audio: English | AC-3 | 384 Kbps
Runtime: 1h 23m 43s
Subtitles: N/A
Samples: Video @ #1 – #2 – #3
Links: iMDB | Trailer | NFO | Torrent Search
Download: NiTROFLARE – UPLOADED – RAPiDGATOR – UploadRocket
Next Post :The New Yorker – September 5, 2016


text:
jRSVP is a tool for Rapid Serial Visual Presentation.
RSVP is based on the notion of displaying a text one word at a time. The words are displayed very quickly after one another.
This supresses the eyes tendency to backtrack the line while reading, searching for the end of the sentence as well as the reader's tendency to oralize the text while reading.
This significantly increases the reading speed..
The Sourceforge page is at http://sourceforge.net/projects/jrsvp/
This webpage is only in the first stages of development. Screenshots and a detailed documentation will follow soon.
The project is hosted by


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I don't know about the rest of you, but having our sport's popularity in the mainstream hinge on a 34-year old street fighter is downright depressing. And the fact that I have gone from people asking if I do that "ultimate fighting" stuff to people asking how fast Kimbo Slice could knock out Mike Tyson is enough to make me want to vomit on my Tapout bed sheets.
In an effort to cheer myself up I started to remind myself of all the awesome MMA in the coming months, with multiple fights having massive implications on the landscape of their respective divisions. The divisional rankings have the potential to be dramatically different between now and the beginning of 2009. Here are nine fights that in my opinion are "must-see" to the die-hard MMA fan. In no particular order……
Tyson Griffin vs. Sean Sherk (155lbs) – UFC 90 Silva vs. Cote
October 25 2008 – Rosemont Illinois
I haven't been this excited for a lightweight battle in the UFC for a very long time. This is a battle between the two best conditioned athletes in the division. It will look like two Tasmanian devils on triple-shot café mochas. The entertainment value of this fight is already through the roof with just the talent level alone, but add in title shot implications and it just raised to drama level to Defcon 1 (which, means we actually had to lower the Defcon level as the drama level rose). This fight is an advertisement for the lightweight division as a whole, and if you are not a fan of the little guys yet, you will be after this one.
Thiago Alves vs. Diego Sanchez (170lbs) – UFC 90 Silva vs. Cote
October 25 2008 – Rosemont Illinois
Many people will argue that the welterweight division is the most talented in the world (in my opinion it's the light heavyweight division, but no one ever asks me) and the UFC has a monopoly on it. This fight features two of the best with the winner getting a title shot and free denture work courtesy of the UFC champion Georges St Pierre. The most overused saying in all of MMA sadly applies here, as this is a classic matchup of striker versus grappler. Alves has evolved into a devastating striker and Sanchez seems to have found his ground-n-pound mojo again, making for an electric clash of styles. It is going to be a doozy!
Thales Leites vs. Goran Reljic (185lbs) – UFC 90 Silva vs. Cote
October 25 2008 – Rosemont Illinois
As with most athletic sports in the world, I believe there are levels of skill that separate one athlete from another. And there is nothing more enjoyable than watching new talent evolve and jump levels right before your eyes. This fight is a perfect example of two extremely talented fighters who are learning to put all aspects of their fight game together and jump to that next level. Leites has world class grappling while Reljic has shown CroCop-like striking which should combine for a fantastic ride. Both have championship caliber upside and with a win here are ready for a showdown with the elite of the middleweight division. Its going to be an interesting tug of war and I can't wait to watch!
Luiz Cane vs. Rameau Thierry Sokoudjou (205lbs)– UFC 89 Bisping vs. Leben
October 18 2008 – Birmingham England
Just as with the fight above, this is a matchup of two talented guys with immense potential who are trying to learn how to put a complete performance together. Cane and Soku are both incredible strikers with knockout power so this promises to turn into a quick match. I doubt either of thses guys will see the third round of this fight, and I wouldn't have it any other way!
Leonard Garcia vs. Jens Pulver (145lbs) – WEC 36 – Faber vs Brown
November 5 2008 – Hollywood, Florida
The WEC has turned into my guilty pleasure in life. I love to watch the smaller guys show off their skills on free TV. While Uriah Faber has proven to be the best in the world at 145lbs (Sorry Kid) the WEC has done a wonderful job of bringing in the best competition around to challenge him. These are two of the best. Pulver versus Garcia pits the two best brawlers at this weight in the same cage together, and fireworks will ensue. Garcia is an energizer bunny with incredible conditioning but has never faced knockout power like Pulver packs in his left hand. Should be an interesting matchup and one I am not going to miss!
Eddie Alvarez vs. Nick Diaz (160lbs) – EliteXC on Showtime
November 8 2008 – Reno, Nevada
The new kid on the block versus the volatile veteran in a battle for the lightweight title will make for a whirlwind battle. Alvarez is coming off of his fantastic Japanese run in the Dream tournament and Diaz is rolling by winning seven out of his last eight fights if you include his win over Takanori Gomi (and I do). Diaz likes to bang on the feet but Alvarez may prove to be too much for him. If Diaz can take this to the ground he way finally have that belt he so desperately desires. But Alvarez is on an unbelievable roll, and his wrestling might be just enough to steal another decision away from Diaz. Should be a good one!
Randy Couture vs. Brock Lesnar (265lbs) – Couture vs. Lesnar UFC 91
November 15 2008 Las Vegas, Nevada
The only main event on my list for obvious reasons. So many sub-plots running here that it will be hard to keep up with everything. Is it too soon for Brock to have this fight? Is the big layoff from action to much for Randy? How will Brock handle actually being punched in the face? Will Brock's size be too much for Randy to control? These and many more questions will be answered that night. The winner gets a shot at Antonio Rodrigo Nogueira or Frank Mir and the undisputed title. I think its safe to say this is the biggest fight of the year hands down.
Quinton Jackson vs. Wanderlei Silva (205lbs) – UFC 92
December 27 2008
Are you kidding me?? Do I need to even tell you why this is a huge fight?? This could be Wanderlei Silva versus Rampage Jackson 27 and I would be the first one there popcorn in hand. This fight is going to be all over the cage and non-stop action. This fight series may down as the greatest trilogy ever, even though it is one-sided so far. This is a must-see for everyone who loves this sport like I do!


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Project may take over some state health exchange functions
Although the Health and Human Services Department's new "NHIN Direct" project might kill a possible revenue stream for some state health information exchanges, those exchanges should be able to make up the revenue in other ways, an HHS official said today.
HHS launched the Nationwide Health Information Network (NHIN) Direct project in March to develop technical specifications for point-to-point secure exchange of patient health data over the Internet. The goal is to allow for doctors and hospitals to directly exchange data electronically on a one-to-one basis with each other or with a lab or a pharmacy.
For some state exchanges that had intended to provide secure point-to-point health data exchange over the Internet to generate revenue, NHIN Direct presents a problem because it will enable that service at a national level, Dr. Doug Fridsma of the HHS Office of the National Coordinator for Health Information Technology said today in an interview. Fridsma is the acting director of the national coordinator's Office of Interoperability and Standards.
However, the state exchanges should realize there are many other services they can provide to make up the lost revenue, Fridsma said.
"NHIN Direct solves one piece of the puzzle," Fridsma said. "There is a host of other things they [state exchanges] can provide for which physicians may be willing to pay."
For example, the state exchanges could generate revenue by aggregating public health data and quality reporting data, by enabling multiparty exchanges and by establishing and providing authoritative directories, Fridsma suggested.
Although some states may have relied on providing point-to-point exchange for revenue in their business plan, that might have been unrealistic because commercial providers are offering similar services, he added.
"A lot of the states have been concerned about [NHIN Direct] removing a revenue stream, but that risk existed before NHIN Direct," Fridsma said.
The draft specifications for NHIN Direct will be released in several weeks, Fridsma said, and this summer organizations will develop software code to facilitate the exchanges. NHIN Direct is an open development project with a public wiki detailing steps in its development.
The project was an outgrowth of an HHS Health IT Policy advisory group's recommendation to set up specifications to help doctors and hospitals meet the criteria to qualify for $17 billion in "meaningful use" incentive payments for health IT under the economic stimulus law. Under HHS regulations, the providers must demonstrate a capability to securely exchange health data electronically to show meaningful use in 2011. NHIN Direct is intended to help them develop that capability quickly, Fridsma said.
NHIN Direct, once completed, will be a component of the NHIN, an HHS system of specifications that allows trusted parties to engage in data exchange and in searches of patient health data over the Internet.
HHS is working with vendors of electronic health records and personal health records (PHRs), as well as with state and federal agencies, on the NHIN Direct specifications, Fridsma said.
"The PHRs are an important part of the health exchange ecosystem," Fridsma said. "They may need to exchange data directly."
About the Author
Alice Lipowicz is a staff writer covering government 2.0, homeland security and other IT policies for Federal Computer Week.
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Meet 21 early-career leaders who are doing great things in federal IT.
See all this year's winners
Alan Balutis and Don Upson debate the wisdom of a cabinet-level IT shop -- and a thorough reorganization of about a dozen other agencies.
The Trump administration's plan to use predictive software to rate threats posed by immigrants, refugees and asylum seekers will result in discriminatory decisions, say a group of privacy advocates and computer scientists.
IT modernization is not only key for federal agencies, but to GSA's Federal Acquisition Service.
The $700 billion defense bill now poised for final passage includes provisions to modernize agency IT through revolving funds and allow for for easy, off-the-shelf Pentagon procurement.
The Vacancies Act sets time limits on the period for acting officials to occupy politically appointed roles -- and some of these officials are about to run out of time.
Census made several key slipups in its decision to award a $283 million mobile device contract for the 2020 population count, according to the Government Accountability Office.
The NHIN Direct Abstract Model (see http://nhindirect.org/ ) defines what is called the "Health Internet Service Provider" as a key facilitator of health information exchange. State HIEs should look at the role this HISP is proposed to play in the system, and see opportunities for which they could be well suited. By participating in the NHIN Direct process, state HIEs can help shape that HISP role.
8251 Greensboro Drive Suite 510, McLean, VA 22102 703-876-5100


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Strategic Affairs Minister Yuval Steinitz addressed the negotiations with the Palestinians and said that "The Palestinian Authority exists thanks to us. Not only because of the Oslo Accords, but because of the funds we transfer them, and the security we give them. Otherwise, Hamas and Islamic Jihad, as they control Gaza, would also taken down Abbas and take over Ramallah."
Steinitz added that "Abbas is simply spitting in our faces." (Noam Dvir)


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I have to check all mine, they pretty well all are 6 options. But I did find one with only 4 options... which might have been one of the 190A ones. And I think I hunted down to find out why it only had 4, and what they were.... but I forget what ever happened about that one now!
From memory I remember something about 4stripes, I think, mentioning how the 190A was good for 8S really and then one I had, or got after, was the one with ony 4 options. From memory..... LOL.
This is the 4 option SS series manual I had found.....
It describes that the 6 option version exists, at the end.
wondering if I pick up tams spinner,shaft,setup does will the HK rotor need much balancing or is it run true with tams kit parts. Thanks Dave
it will run truer but of the 50 or so 70/10 rotors I've balanced not one was to exceptable levels out of the package this is because they are not balanced from the factory, they come out of the mold and go into the package. I will say though they are very uniform in that they always need around the same amount of weight and in the same spot from rotor to rotor, sometimes I get one that is heavy in the front plane or rear plane really bad these ones are harder to balance properly. one way to tell if you have one of these or just have a front to back out of balance is to use your static magnetic balancer that most people use and when you spin it on their it will come to a stop and then by itself start running backwards for a few revolutions this is an indication that your front to back balance is off. these are practically impossible to get right at home using a static balancer. one option is to send your rotor to Tam and pay him to dynamically two plane balance it, the service is 25 bucks and is worth it especially if you already have the precision adapter, spinner washer and spinner.
I have not bought anything from Tam yet,I do have fan and a couple motors coming soon. I will check the balance and see how it is on my magnetic balancer before I decide what to do. Im just looking to put it in a old het f18
Right so now all the readers need to 2 plane balance their rotors or their fans wont be any good
Wemotec have been doing it for years, HET too, but 9 times out of 10 you drop their rotors onto a 3.17mm adapter or shaft and still need to rotate them in order to cancel out mechanical resonances from the parts interaction. Same with their spinners, you cannot just drop them on as you will 9 out of 10 get a mechanical resonance around 1/4 throttle, rotate the spinner and usually you can cancel out the resonances, when you cannot get them all out a simple dynamic balancing of the spinner on the fan will finish it off.
But hey, drop it onto a 5mm shaft and its amazing! Little to no adjustment needed because the shaft is so huge & inert for this size of fan. Even 4mm shafts are a huge improvement over 3.17, hopefully more motor manufacturers will move to 4-5mm shafts.
The end user can easily balance any rotor statically and get the fan to run perfectly smooth, they just need a precision ground shaft for their magnetic balancer, and a precision machined hub to fit each rotor type. Engineering plastic with a uniform density is perfect for machining up hubs as its light and accurate. Of course most people cannot source or make these parts but that doesnt mean its not possible for them to do it. Once they have the rotor running smoothly its not hard to finish off the spinner with tape weight internally.
It was a bit of an exaggeration of the original text.....
It wasn't implied that it was required to have them 2-plane balanced to be acceptable... it sounded more like a suggestion (advice at most) of something you might want to do (and jcdfrd/Tam do) in a quest for 'perfection'.
That is getting into pretty fine detail.... too much for me to ever bother doing!!
And I couldn't technically refute its merit, but I would lean on Mark's side of the fence and think it is 'swamped' by other aspects of the situation that would make it hard to tell a difference and to matter.
But jcdfrd and Tam suggesting they can measure it.... so I guess it is a fact. It is more a matter of how important a factor/fact it really is to most other users. Seemingly zero real-world importance to Mark (LOL), and to me also really. That is just getting too fine and finnicky for me to apply effort to pursue, versus my guesstimated minor benefit it would give.
Like some other posters I have seen mention, I am getting great results even from stock fans - with just minor clock method adjusting. No static balancing.... and no reverberations.... sound great... input/output ratios as good as any others I see posted about....
But if you wanted perfection.......... And especially when that is getting more important at the very high end of power outputs, it likely would be starting to be something more than 'zero' use.
yes Peter we can measure it and it does make a difference, you can see for yourself if your interested....get tams setup and run it against your own setup.....you will feel and hear the diff for yourself.....or not, its no skin off my nose I only offer my own experience
That is awesome! WOW.
Now I will have to go and crawl in a corner with my "Probably 0.15" balanced rotors! LOL
Even though at my level they are probably totally fine anyway.
But that is impressive testing and work level by Tam! Certainly looks like it is worth the cost - it is just a matter of whether a user can justify/want/need that cost. More so when International postage and time also add into it all.
I hate it when you just 'need' to do something, to find out how much it matters. LOL.
Versus "Seems ok, or fine" as it is.... and you might just find out it is not quite as "ok, or fine" as you thought.
So that setup pretty well shows the 2-planes are measurable at least. And then suggest that will come into play to some degree - and even more so as you aim to get higher output loads.
And all this time, I thought it was my magnetic balancer. What you've explained is exactly what is happening to mine. I learned something new. Thanks!
Yes, that`s cool to know, about the rotor reversing rotation on it`s own. I`ve seen that many times and had no clue what it was happening. Great info, thanks.
Also the video is very interesting too. I have a feeling that I will be sending Tam some rotors to balance for me pretty soon. That`s very impressive.
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Seville, Spain Lawyers and Law Firms
Seville, Spain Lawyers
Cuatrecasas, Goncalves Pereira
Full Service Law Firm in Spain+34 954 501 414
Cuatrecasas, Goncalves Pereira is home to the general management and directorship of Cuatrecasas, Gonçalves Pereira in Spain. Located centrally at the intersection of Paseo de Gracia and Avenida Diagonal, the firm works in two of Barcelona's emblematic structures: the Edificio Europa and the...
Law Firm's Overview
Full-Service Law Firm in Madrid, Spain+34 95 448 93 48
Garrigues is both the foremost global legal services firm in the Iberian Peninsula and the firm with the longest-standing tradition. As a result of sustained growth throughout the last six decades, it is today the leading firm in terms of number of professionals and billings.
Our human resources...
Law Firm's Overview
Adarve Corporacion JuridicaSeville, Spain
Corporate, Commercial, Real Estate & Tax Law+34 95 4323374
Adarve Corporación Jurídica was established in 1999 as a result of a merger between the law offices of Garcia-Lima & Associates, and José Fernando Cornejo Pablos, both located in Madrid and with over 25 years of experience. Always working under the principles of honesty, responsibility, and...
BrosaSeville, Spain+34-954-286-099
Bufete GénovaSeville, Spain
Bankruptcy, Family, Litigation, Commercial and Corporate Lawyers in Spain+34 (954) 274-443
Bufete Génova's founding has been characterized by an ongoing commitment to growth based on providing services characterized by high technical legal quality, coupled with a friendly and personalized situation serves to generate trust and loyalty with our customers, trying to anticipate their...
Buleto, Mauduit & GallegoSeville, Spain
Full-Service, Litigation Law Firm in Seville, Spain+34 955641117
Buleto, Mauduit & Gallego is a full-service law firm, providing legal advise and defense in every jurisdiction. We are heirs of the best forensic tradition coming from don Juan Mauduit, well-known and honorable attorney in Seville, Spain, since 1949. Our Firm has created a network of the best...
GPV AbogadosSeville, Spain
Full-Service Law Firm in Seville, Spain+34 955135387
GPV Abogados Law Firm deals with Divorce, Family Law, Financial Disputes, Pre-Nups, Children Issues, Financial settlements and Medical Negligence.
S.Llamas y AsociadosSeville, Spain
Tax and Legal Services Lawyers in Seville+34 954 219452
S.Llamas & Associates was founded in 1995 with a mission to serve its customers, providing professional services and auditing financial and tax advice with the aim of advising, prevent and, if necessary, to solve the problems that arise in the operation of companies and organizations.; The founding...
Sevilla LawyersSeville, Spain
Full-Service Law Firm in Seville, Spain+34 (955) 710-203
Sevilla Lawyers offer the best service in assistance aimed at both individuals and to all legal persons (companies, businesses, communities of owners, etc.), Assistance to reveal the subject of consultation questions and solve their legal problems, through counseling, mediation and trial...


text:
The only good thing to come from the pretention-fest that is sure to be Terrence Malick's new movie, The Tree of Life, is that it forces Angelina Jolie to leave her other job as the queen bee that constantly craps out Brad Pitt's larvae. Here she is, escaping the hive for a night and actually trying to look decent. How I've missed you, Angie.
Other than Angelina Jolie's coming out party, there's really no other reason to be excited for Tree of Life. Word is ginger hottie, Jessica Chastain, doesn't even get naked. Not even half a nip. Malick's clearly losing his cinematic touch. Enjoy.


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RIO DE JANEIRO, Sept 27 (Reuters) - Brazilian state-controlled water and sewage utility Sanepar is preparing a plan to sell about 1.5 billion reais ($463 million) of new and existing stock, the Valor Economico newspaper reported on Tuesday, citing unnamed banking sources.
The sale could be the biggest stock offering in Brazil this year, the paper said.
The offering would provide capital for investment and allow the controlling shareholder, the government of Brazil's Parana state, to raise cash, Valor said.
A bill passed last week by the Parana legislature allows the government to sell shares in state-owned and -controlled companies, but requires the state to maintain at least 60 percent of the common stock in Cia de Saneamento do Parana, as Sanepar is formally known.
The bill, aimed at helping the state raise revenue in the midst of budget difficulties, still requires approval from Parana's governor.
The state owns 75 percent of Sanepar's voting, common shares. When non-voting preferred stock is included, it owns 51.4 percent of the company's total shares.
On Monday, Sanepar preferred shares, the company's most-traded class of stock, closed at 8.30 reais. That gave the company a market value of 3.34 billion reais, Valor said.
$1 = 3.2416 Brazilian reais Reporting by Jeb Blount; Editing by Lisa Von Ahn


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Sign up for our daily recaps of the ever-changing search marketing landscape.
Proximic ("Don't Call It A Newsreader") Moves Into Mobile Search
Contextual content and advertising provider Proximic released an iPhone app, as the first step into a much broader foray into consumer-facing mobile search. The company's underlying technology is called "pattern proximity matching," which seeks to better understand pages and context through numerous points of relevance.
Company CEO Philipp Pieper says that it can be used to match ads with content (or content with other content) but that it also offers a superior relevance algorithm for consumer search. However the new iPhone App "Proximic Agents" isn't yet a full-blown search engine; it's a more intelligent news reader — for now.
Here's how the company describes the new iPhone app:
The Agents app is an intelligent news service for better daily productivity. Proximic will scour millions of RSS feeds to find relevant content. Agents then match your interests and deliver fresh information directly on your iPhone.
Users set up queries or search terms ("agents"), very much like current news alerts. Wikipedia and news feeds are indexed and dynamically presented to end users who can save or share queries/results. Results may be sorted by relevance or date. But in the near term location awareness will be incorporated as another layer of relevance and factor into how results are defined and presented as well.
Search queries may be stored and retrieved under the "agents" button (upper left of the screen). The interesting thing is that the app doesn't call itself a search engine but that's largely how it presents itself to iPhone users. Over time it will become more like a search engine, with more data sources and more use cases. Users who set it up as a news reader will today have a better experience than those seeking to use it as they would a mobile search engine.
Proximic's Pieper stressed that the technology was "language independent" and the company is making a big push into China where manually entering queries into a mobile phone is impossibly challenging.
Beyond the iPhone the company will be expanding onto other smartphone platforms and incorporating the camera as an input mechanism for things like product search. Android app ShopSavvy incorporates conventional barcode scanning through the camera today. There are also mobile applications that read QR codes and provide a broad range of content and information about places, objects and products.
Pieper and I also discussed so-called "augmented reality" — users point their phone's camera at an object, building, landmark, etc, and get information and content about it displayed on the phone's screen in real time — and how Promixic might "play" in this arena. The Android G1's compass feature is a rudimentary version of this capability.
As the company develops these new features and incorporates more data sources it will likely evolve into a mobile search engine and become less of a news reader. Right now, however, it's a fascinating hybrid and whether you like it or not may well depend on whether you see it as a news reader or as a mobile search engine.
We're listening.
Have something to say about this article? Share it with us on Facebook, Twitter or our LinkedIn Group.


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Tokuya Omi0000-0001-6147-6609
Tokuya Omi has graduated from Nippon Medical School in Bunkyo, Tokyo, Japan in 1988, and in 1992 he has been a graduate of Nippon Medical Graduate School. From 1992 to 1996, he was a Dermatology Assistant at Nippon Medical School Hospital, Japan. Omi was a Visiting Research Professor at Aarhus University, Denmark in 1996. Moreover, he was the Director of the Department of Dermatology at Queen's Square Medical Center, Yokohama, Japan in 1997. During the period from 2000 to 2006, he was a Lecturer at Nippon Medical School. In 2006, he was an Associate Professor at Nippon Medical School.
Biography Updated on 1 June 2009


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Nights out in Leeds frequently involve the wearing of trowel-thick layers of make-up and scantily arranged rags of clothing.
But they rarely end up at a giant party for the undead, hanging out with a posse of zombies.
This is the finale I envisage for my evening of adventure with 2.8 Hours Later, which will be flooding the city with sufferers of partially deceased syndrome for a series of adrenaline-fuelled zombie runs this week.
The company specialises in hosting apocalyptic events where participants are given a city map and a set of clues, then let loose to dodge hordes of the undead in order to reach their target.
In certain areas of Leeds the streets will be overrun with crowds of moaning shufflers whose vacant, dead-eyed stares flash with murderous intent.
Some would say that's business as usual – although the relentless pursuit of brains certainly sets the zombies apart from your average bloke-on-the-pull down Greek Street on a Saturday night.
I can't wait to pound the streets in desperate flight from the hordes of volunteer zombies recruited by 2.8 Hours Later this Friday night.
And the after-party sounds awesome too.
(Though it would be even more amazing to experience the evening in full shuffle mode from the outset, as one of the volunteers. They have to go to zombie school! Where they are 'taught to run, chase, scream and bite like true undead champions'! And it's all organised by the Inhuman Resources Manager! Jobs don't come much cooler than that.)
But what does it say about our society, this pervasive obsession with the zombie apocalypse?
Brad Pitt's new movie World War Z also plays on our creeping fascination with an undead Armageddon. Images of mass contamination, unchecked brutality and apocalyptic extinction seem to be scratching a societal itch somehow.
As the king of the undead George Romero (director of Night of the Living Dead) put it himself: 'Zombies represent a global disaster that people simply don't know how to deal with'.
Whether it's a portent of impending environmental doom, symbol of unchecked consumerism, or signifier of a global pandemic – the zombie apocalypse certainly provides a rich subject for reflection.
I always enjoyed engaging in zombie chit-chat with my former boss – a bloke even more obsessed with apocalyptic scenarios than me.
Whereas I had my escape route all sorted (not that I plan to reveal it here, of course. I don't stockpile extra cans of Alphabetti Spaghetti for just anyone, you know…), he was ready to stay and fight.
A motorbiking psychiatric nurse with a penchant for martial arts, my boss could handle himself in a scrap.
Yet his strategy seemed foolhardy in the extreme. Not only did he plan to take on the zombies himself, he was also training his cherubic, golden-haired sons (still toddlers at the time) to take on the living dead bare-handed.
('They won't be expecting ankle biters,' he crowed. 'That'll give those brain-eating blighters a shock.')
However we approach the impending demise of the human race, one thing is for sure. A night of joy and absurdity, spent boogying with hundreds of gyrating zombies, has to represent some sort of triumph over doubt and fear – and, there amidst the undead, I hope to celebrate feeling truly alive.