text:
Join spankwire.com today for FREE, and gain added functionality
that members enjoy.
Passwords are case sensitive.
good sloppy finish
shes fun
ahhh FUUUCK...LOL
damn girl
Agnost upload more suck it drys and jugg fuckers the more the bettter im waitin on it
oo. need the next scene after
its a turn off for me when its sloppy joe style....and hearin that shiat makes me wanna puke but only when its on somebody else...lol not on me..haha
sucks dick like a champ
nasty indeed and what a great sloppy finish
perfect. That's the girl for me.
Help improve Spankwire by telling us who
the stars are in this video.
Pornstars are added once we get
enough submissions with the same name.
Privacy Policy | Terms of Use | 18 U.S.C. 2257 |
Contact | DMCA
| Feedback | Mobile version | Sitemap


text: BULLETINSBulletin 1Bulletin 2 LANE CONDITIONSThe Technical Delegate for the two World Championships in Henderson/Las Vegas in August 2013, Marios Nicolaides, has now decided the two categories of oiling pattern.World Championships at Strike Zone, Henderson will be played on Short and Medium categories. The lane conditions picked were the 33-foot Sydney pattern and 39-foot Seoul pattern.The definite patterns within the two selected categories will be announced at the Team Managers meetings immediately before each championship.The lane machine that will be used will be a Kegel ION Sport model with the new DUO transfer system. Ice oil will be used and the cleaner will be Defense-C.For lane mapping data for Sunset Station, click here. LIST OF DELEGATIONSFind out who is coming to the World Championships PRO AMLearn more about the Strike Gold Celebrity ChallengeStrike Gold Celebrity Challenge entry form

subset: commoncrawl


text:
Send to a Friend
Regarding Michael Brown Ferguson incident, what fallacy is being used to justify this statement?
Asked by pleiades (6571) August 16th, 2014
I don't think it's the False Equivalence fallacy… Or is it??
Here is the statement made on FaceBook by a guy who felt like jabber jawing with an old professors comment wall after she changed her profile picture to a photograph of Michael Brown.
"I feel sorry for this young man's family…when will people learn that committing strong arm robbery and attacking police officers is never a good idea…"
Using Fluther


text:
Even and odd days of gas rationing in the 70's, could look like a piece of cake..
The U.S. is due to pull out of Iraq by year end, and Special Forces say - they are ready - the training has been done and then - it's out of our hands. I can certainly see how sectarian war could spread across the region and really escalate once the U.S. withdraws. Spare oil capacity will likely disappear this Summer, and I can just imagine what will happen if there's a sectarian war across the Middle East. For the U.S. - It could be much worse than the gas rationing days of the 70's..
Iraq's Maliki says Bahrain may ignite sectarian war
© Thomson Reuters 2011 All rights reserved
|return to message board, top of board


text:
It's a weekday afternoon in the poker room at the Bellagio Hotel & Casino, and something strange is going on: It's packed. The 30 tables wedged into a far corner of the casino...
LAS VEGAS — It's a weekday afternoon in the poker room at the Bellagio Hotel & Casino, and something strange is going on: It's packed.
The 30 tables wedged into a far corner of the casino are filled, mostly with young and middle-aged men clicking chips and shuffling cards, as a line of people waiting to ante up spills out the door.
"The game has been revived," said Bill Thompson, a public-administration professor at the University of Nevada, Las Vegas, and author of a gambling encyclopedia. "Until the last four or five years, [poker] had sort of been an old man's game for Friday nights."
Most Read Stories
- Seattle's income tax on the wealthy is illegal, judge rules
- Analysis: Five reasons the Seahawks waived Dwight Freeney WATCH
- Retired Alabama cop on Roy Moore: 'We were also told to ... make sure that he didn't hang around the cheerleaders' | National politics
- Jobs that pay without a B.A.: the most lucrative fields in Washington state
- A Washington syrah was named second best wine in the world
But thanks to televised tournaments and a handful of celebrity card players lending glamour to the game, poker has exploded into popular culture — forcing Vegas casinos to jump on the bandwagon.
Caesars Palace is expected to announce plans to open its first poker room in more than a decade. The MGM Grand will reopen its poker room — closed for years — in March. Bally's unveiled new poker tables over the summer, and the Mirage added more tables. Several other Strip casinos are considering expanding their poker operations or creating new ones.
"You can't find a casino in Vegas that isn't scrambling to open up a poker room in order to get people in it," said Steven Lipscomb, creator of the televised World Poker Tour and president of WPT Enterprises.
Most players deal in Texas hold 'em, seven-card stud or Omaha, with bets starting at a few dollars and reaching thousands of dollars.
Don McGhie, a gaming consultant, said poker accounted for a small percentage of a casino's profits and that the rooms usually were buried in casinos' nooks and crannies.
To make money off poker, a game where players compete against one another, casinos skim a percentage of a table's winnings, charge a fee per hand or, in higher-stakes games, charge for the time a table is used.
But expanding poker offerings isn't only about cashing in; it also entices a new generation of gamblers to Sin City.
"Poker is more of an experience," said Scott Ghertner, director of sports and promotions for MGM Mirage.
And it's a safe bet that some poker players will wander into the craps and blackjack pits — pouring easy money into casino coffers — when they're not holding out for the next flush.
"It's such a popular game right now; it's driving a lot of patrons into these properties," said Dennis Neilander, chairman of the Nevada gaming-control board.
As the game favored by cowboys and World War II soldiers faded in popularity, many casinos folded their poker rooms in the 1990s, replacing them with more lucrative slot machines, Thompson said.
But the World Poker Tour and World Series of Poker — where regular-guy amateurs have taken home championship millions — and Bravo's "Celebrity Poker Showdown" have hooked a new, younger viewing audience on the classic card game. The WPT's "Battle of Champions," which aired on NBC in February, drew an estimated 10 million viewers.
"It just exploded," said Jack McClelland, poker-tournament director at the Bellagio and a 28-year industry veteran. Lipscomb described the game's renaissance as a "social phenomenon."
The World Series of Poker competition at Binion's Horseshoe Hotel & Casino used to draw several hundred contestants, but more than 2,500 card players raised the stakes this year, competing for nearly $50 million in prize money. The World Poker Tour on the Travel Channel, which employs a tiny camera that reveals players' face-down "hole" cards, went from 14 tournaments and $10 million in prize money in 2002-03 to 16 planned tournaments worth $70 million this year.
"Real people can relate to it," McClelland said. "They can see it happening to them."


text:
kdcarverwrote a question about Tentsile Connect Tent: 2-Person 4-Season on March 19, 2015
Is there a maximum or minimum height off the ground for suspension?
Is there a maximum or minimum height off the ground for suspension?
What is the snow load capability of the suspended tent?
What is the typical method to access the tent when it is suspended? A rope in the center hole?
Does the jacket reach approximately to the knees?
How long is the trench? Does it reach past the knees?
How long is the jacket? Does it reach past the knees?
Purchased this boot to use during a week of light hiking in the Shenandoah Nat Park, and also be able to use them at casual outings during at wedding in DC that weekend (didn't want to pack a lot of shoes). Served their purpose well.
I have narrow feet, and these fit fairly well, but I have to use a pair of Superfeet to add to the factory inserts to take up the volume. The shank feels like a half shank, but provides good support for light hiking.
The boots are nice enough to wear with a pair of khakis.
0 Comments
What are the measurements of the trench? Specifically, how long is it? (i.e. is it mid calf or knee length?)
Do these sandals run wide or narrow?
0 Answers
However, the belt is stiff and a bit long.
0 Comments
Lightweight, breathable. Great for all but hot weather. DOESN'T retain odor, even after many days of use.
0 Comments
Well made, comfortable, will not hold odor.
0 Comments
The pant is made of tough, but is not too heavy of a fabric. It bends and moves well. Suspenders are sturdy and comfortable. Unfortunately, the "hook and loop" tabs on the side don't hold well when you attempt to vent the pant. The vent zips only work one direction as well. The thigh pocket arrived with the inside not sewed together -- thus you had a pocket space that extended down the lining to the ankle. Called Columbia - they are helpful and informed me this was a defect. I ended up with a Patagonia Primo Flash pant -- expensive, and light, but it performed very well with a good set of wool underwear.
0 Comments
I looked at several different pants for skiing/boarding this year. I settled on the Primo Flash for the following reasons: The pant is comfortable and fairly tough with good reinforcement in key areas (rear, sides of cuffs). The pant moves and bends easily without binding. The crotch is a little short, but this seems to work itself out with use (even with thick thermals underneath). The pant is light enough to give you options in layering. Venting is excellent on the sides (not full, however), and allows for a "bombbay" option if necessary. Suspenders at a bit problematic and "light" at first use... but seem to work fine after you get used to them. Good pockets to store gear. Only complaint -- no zipper storm flaps. Even "sealed zippers" will start to leak over time, and a flap would be an improvement in my opinion. Overall, a great pant, and they performed well (even if I didn't!) on the slopes of Mt Werner this year.
0 Comments
These are really tough pants. Side vents are full length and allow a "bombbay" approach if you are stuck in the middle of nowhere and need to "do your business"
I like the zipper flaps as opposed to other pants which use trendy "sealed" zippers (time = no seal).
Suspenders seem weak/light at first, and get tangled, but after a bit of experience, they work fine.
I sent these back because they only have two pockets and they are VERY heavy compared to other similar pants. They'd be ok in extreme cold and if you don't have to move much (snowmobiling?). In any other circumstance, I would expect to be sweating from the combination of insulation and having to heft their mass.
0 Comments


text:
Tractor Supply Company to Participate in Two March Conferences
Feb 29, 2012, 16:36 ET from Tractor Supply Company
BRENTWOOD, Tenn., Feb. 29, 2012 /PRNewswire/ -- Tractor Supply Company (NASDAQ: TSCO), the largest retail farm and ranch store chain in the United States, today announced its participation in two conferences to be held in March.
Raymond James 33rd Annual Institutional Investors Conference will be held on Monday, March 5. Tony Crudele, Chief Financial Officer, and Randy Guiler, Director of Investor Relations, will attend this conference. The Company's 30-minute webcast presentation will begin at 1:05 p.m. Eastern Time.
Bank of America Merrill Lynch 2012 Consumer & Retail Conference will be held on Wednesday, March 7. Jim Wright, Chairman & Chief Executive Officer, and Christine Skold, Vice President of Investor Relations, will attend this conference. The Company's 40-minute webcast presentation will begin at 9:50 a.m. Eastern Time.
For both conferences, a webcast of the presentation will be available on the Company's website at TractorSupply.com, and an archive of the webcast will be accessible for 30 days.
About Tractor Supply Company
At December 31, 2011, Tractor Supply Company operated 1,085 stores in 44 states. The Company's stores are focused on supplying the lifestyle needs of recreational farmers and ranchers. The Company also serves the maintenance needs of those who enjoy the rural lifestyle, as well as tradesmen and small businesses. Stores are located in towns outlying major metropolitan markets and in rural communities. The Company offers the following comprehensive selection of merchandise: (1) equine, pet and small animal products, including items necessary for their health, care, growth and containment; (2) hardware, truck, towing and tool products; (3) seasonal products, including lawn and garden items, power equipment, gifts and toys; (4) maintenance products for agricultural and rural use; and (5) work/recreational clothing and footwear.
SOURCE Tractor Supply Company


text:
WHAT: The Eight Annual ORVG Spring Roundup.
HUH?: If you've not been to a RU think..........
Family Reunion (where you choose your Family),
Picnic with tables and tables of unneeded, absolutely delicious calories.....
Plant/Craft Swap/Gifting
Want to add to your Plant Collection, Share your favorite Plants, Chickens or Crafts....this is the place and the time.
Just starting out, have nothing to share and need to add some prime Foliage to your new garden
(grown by some of the Midwest's best Gardeners) don't be shy there's ALWAYS plenty to go around.
WHO: All DG Members, Their Family and Friends
Come Join US!
WHEN: Saturday, May 26, 2012 (Rain or Shine we have a shelter!)
TIME: 10AM-Dusk LUNCH at 12:30
WHERE: Chilo Lock #34 Park
521 County Park Road
Chilo, OH 45112
Separate Threads will be put up in the next few days for attendance, food, trades, etc.....
This message was edited Apr 22, 2012 2:35 PM
Please come join us for the 8TH Annual ORVG SPRING ROUNDUP!
WHAT: The Eight Annual ORVG Spring Roundup.
I gotcha covered. Drat...another that I will miss!! Jo
Could we use this for a who's coming page?
Yes we can Joyce.
Robyn and I will be attending.
Jessica and i will be there too. maybe Lucy and the kids too LOL
I will be there and Marsh probably will. It gives him a chance to eat things his wife normally does not allow, lol.
I'll be there. I missed last year because of my parents. So looking forward to seeing my good gardening friends! ^_^
Dan and I will be there.
Dave and I plan to attend.
Good Deal!
We may be bringing Drudwyn as the Daycare isn't open on Saturdays.
Still a little 'new' to be left alone long.
Bob and I are looking forward to this.
We plan to be there...Dave n I!
I had a thought, maybe I should of left it to die of loneliness, but what about have a silent auction, regular auction or garage sale type sale, and having the attendees bring something or things that they no longer need, and donating the proceeds to Gigi's garden fund? JUst a thought! Lou
Did anyone contact Lilyhostaky- Paulette? She usually comes with her family. I think from her page that she is not a subscriber anymore, but is in cubits?
I know Ric had mentioned trying to reach her.
I love the idea of the auction. I'm gathering things in my head right now!
Just talked to her as a matter of fact.
She had eye surgery and is doing very well now.
She may be there Saturday.... I'll call her tomorrow to find out.
Lou, since you had the original idea, will you also be conducting the auction or sale? How do you envision it?
I was hoping we could draft someone to play auctioneer. If not , I thought maybe everyone could just auction off their own stuff by taking turns. That way we would know all about the item. Lou
Hi, again, everyone,
Just wanted to RSVP that Buz and I will be coming by for a visit--probably arrive on the early side. Looking forward to seeing everyone!
And I'll bring a plate of chicken and veggie wraps if anyone thinks that's a good idea.
See you tomorrow! J.
Sounds good! It will be good to see you both! Lou
Checking in...Meyer, party of 9 and possibly a guest.
Once again the ORV RU was a wonderful DG event and so fun to see everyone again! I'm so glad we were able to stop by for a visit!
And thanks for all the organizers and plant trading enthusiasts! You made it lots of fun!
I can't believe it's the Eighth Annual RU for us! Hugs, t.
More Ohio River Valley Gardening Threads
Any ripe tomatoes?started by tabasco
last post by tabascoSep 18, 20171Sep 18, 2017
when to plant seeds of native wildflowersstarted by amygirl
last post by amygirlSep 25, 20172Sep 25, 2017


text:
I want to create my own ISP. Where do I start. I want a good search tag from where i should start searching.
I have 2 modems and 2 dongles. I want to connect to the internet on my own. What I want is to connect to the internet with unlimited speed and data. This seems crazy but I want to do something.
ISP. Where to start?
|Sampan Verma · May 24, 2015
Post a Reply
Replies- page 1
|Oldest Newest Rating
Cardinal Coog
· June 4, 2015
I'll try to be nicer if you try to be smarter.
Jonas Meise
· June 4, 2015
If you want a good Internet connection you just have to choose a good provider. And if you want to download movies or other things with fast speed maybe shareonline is something for you.
With a good provider and a shareonline account I can download stuff with about 10 Mbps and that is totally more than enough.
Also it doesn't cost much.
Cardinal Coog
· June 2, 2015
Basically, you would need to lease lines through your local Telco. At very minimum, you could start with a few T-1s or a T-3 (lines/switches). Maybe upgrade to an OC-48 or higher. You'll never get "unlimited" speed. That's a question of relevancy though.
You could look online, maybe ebay, for a Livingston PortMaster-3 or 4. Pick up a few Linux boxes.
But, from a business standpoint, starting an ISP is cost prohibitive. In the U.S. we have oligopolies which means there are a handful of large enterprises (corporations) with more money than common sense that you would need to compete against (ie. Time Warner, AT&T, etc.)
Those two modems in your mom's basement ain't gonna work
Cardinal Coog
· June 2, 2015
Nevermind... I remember you now... You're the one that can't open a cracked video game. Now, you want to start your own ISP. ROFLMAO!!!!!!!!!!!!!!!!
Sampan Verma
· June 3, 2015
starting an ISP and cracking a game are two different things. Moreover it is really a pain in *** to download GTA5 and Far Cry4. GTA 5 has been fixed as I had to change my date to 15-April-2015 and for Far Cry 4, I need DirectX 11 compatible GPU which I dont. I bought a new PC for Far Cry 4.
Cardinal Coog
· June 3, 2015
Wow, I learn something new everyday. I never knew the difference.... I hear NASA is hiring.....
Sampan Verma
· June 3, 2015
Have ever been connected to the internet when you not paid for it and just cracked into some internet tower or sth? for {Cardinal Coog}
Sampan Verma
· June 3, 2015
I just want to make sth that will just help me connect to the internet with appropriate download speed (100kbps-1mbps) at really low price that can be 50 Rs(~1$). Download data should be unlimited with that speed {most important}.
Intenet is not just a need. It is our Right.
Sampan Verma
· June 3, 2015
And NASA is hiring... who? why? how? where?
Cardinal Coog
· June 3, 2015
I kinda like you.
You're like a midget, a clown, and a donkey all wrapped into one.
- 1
- 2
General Chat
129,727 followers
Chat about anything non-computer related including, music, movies, tuna sandwiches, and more!
|Bucky Roberts Administrator


text:
Mt Emily work party 10-15-10
Back in April there were several spots of damage reported on Mount Emily. NEO 4Wheelers were in contact with the forest service about helping with restoration when the time came. The forest service went in with heavy equipment and leveled out many of the spots and we went up yesterday to spread seed, lay down straw cover, and block access to some of the damaged areas.
Law enforcment added patrols to the area and yesterday we found out one citation was handed out.
we had a truck load and a trailer load of straw that was donated
we had 7 club members, 2 kids, and about 7 volunteers from the forest service
we split up into 2 groups to cover more area
we met back up at an area they werent able to get equipment into
headed back out to the first area we dropped some bales off at, people ate lunch and then it was back to work
after this most of us from the club headed into La Grande and grabbed some pizza.
It was a good time, had really nice weather, and got some good work done.
some of the names are wrong but heres a newspaper article from the work day.
Scars left by vandals on U.S. Forest Service land on Mount Emily should heal up nicely, thanks to a group of four-wheel drive enthusiasts who want people to think the best, not the worst, of their sport.
Members of the Northeast Oregon Four Wheelers showed up in force on Three Cabin Ridge Friday, spreading seed and mulch over land that was extensively damaged last spring by vandals in four-wheel drive rigs.
The club came out with one thing in mind: to show the community that the majority of people taking all-terrain, four-wheel drive vehicles into the mountains do respect the land.
Its important for us to set the tone for four-wheelers, said club member Jamie Wilson. The more damage is done, the more the state will want to close down Class II trails.
Last April, the Forest Service discovered that particularly heavy damage had been done in the Robbs Hill-Three Cabin Ridge area of Mount Emily.
In about a dozen places, drivers out for a good time had taken their rigs into open meadows, spun their wheels in the mud and cut gashes that in some spots were more than two-feet deep.
Kurt Wiedenmann, the Wallowa-Whitman National Forests La Grande district ranger, was outraged. In a newspaper article, he detailed the damage and warned that the Forest Service would institute an emergency closure of the area if the vandalism didnt stop.
Wiedenmann said Friday that public reaction was swift and overwhelmingly positive. The Forest Service and local law enforcement received numerous tips. In one case, a juvenile four-wheeler was caught in the act of tearing up the land, prosecuted and fined.
At least one of the calls was about undoing damage.
The Northeast Oregon Four Wheelers, made up of people who use Class II all-terrain vehicles four-wheel drive trucks formed last November.
Today, the group boasts about 15 members in cities from Hermiston to Ontario. Theyve come together to share experiences and protect their right to enjoy their hobby.
A bunch of us met over the Internet and got to talking. There wasnt a club, so we started one, said member Colton Wiseman, Ontario.
In La Grande, club member Leslie Garoutte read the newspaper article. After conferring with club members, she contacted Wiedenmann with an offer to help with the rehabilitation.
She said the idea was to show that most four-wheel enthusiasts are good land stewards.
Our club was in the early stages. We knew about the damage and doing this for community service was something we were all into, she said.
Fridays work was supervised by Penny Hall, a botanist for the Wallowa-Whitman. As club members loaded up sacks of seed and carried them to the damaged areas, she talked a little about the restoration effort.
She said ruts had been filled in with woody debris earlier. Club members were tasked with spreading locally-collected seed, and laying down straw for mulch.
By the end of next summer we should see some above-ground growth, Hall said. Eventually it will all blend in.
Wiedenmann said that the Forest Service hasnt seen much more damage in the area since last spring. Though he did not call an emergency closure, a gate was installed at Forest Service Roads 8405 and 035 and could be locked during wet seasons if problems continue.
We havent had any problems since. Were monitoring it and if theres indication of a lot of mudding, well do an emergency closure, he said.
He said the Forest Service greatly appreciates the help from the club.
Its a project thats been a long time in the making. They use the area and doing this is important to them, he said.
Congrats! I saw this morning that your work party got on the news last night. It was on fox 12 in portland, or. I would post a link but im not sure on how to do it.
Again, great job and keep it up!!!!!
That's awsome, ill have to look for that
|All times are GMT -7. The time now is 05:53 AM.
Powered by vBulletin® Version 3.7.4
Copyright ©2000 - 2017, Jelsoft Enterprises Ltd.


text:
Appalachian Trail Cook Tent, Millinocket, 1935
This photograph is of the 193rd Company of the Civilian Conservation Corps' (CCC) Cook Tent on the Appalachian Trail in Millinocket Maine.
The back of the photograph reads, " Not he Waldorf but the food was good & plentiful."
William Wolff, Jr. sent this photograph in response to a CCC Reunion invitation from Norman Wetherington in 1985.
Please post your comment below to share with others. If you'd like to privately share a comment or correction with MMN staff, please use this form.


text:
Protein tyrosine phosphatases (PTPs) are now recognized to be involved in a multitude of signaling events that control fundamental biological processes such as cell growth, differentiation, apoptosis, and cell movement. PTPs, which were initially thought to be less discriminating in their actions compared with their protein tyrosine kinase counterparts, are now known to regulate these various biological processes in a precise manner. This review will focus on the concept that PTPs exhibit remarkable signaling specificity through intrinsic differences between their PTP domains and through various modes of regulation that endows them with the capacity to promote unique physiological responses.
Review focusing on the concept that PTPs exhibit remarkable signaling specificity through intrinsic differences between their PTP domains and through various modes of regulation that endow them with the capacity to promote unique physiological responses.
Intracellular signaling pathways that are mediated by tyrosyl phosphorylation are controlled through the balanced and opposing actions of protein tyrosine kinases (PTKs) and protein tyrosine phosphatases (PTPs). The view that PTPs are equal contributing partners in the regulation of cellular tyrosyl phosphorylation continues to mature. However, there still remains the perception that PTPs play largely housekeeping roles. A growing body of evidence firmly dispels this perception, and it is evident that PTPs function with stringent signaling specificity, in concert with their PTK counterparts, to define specific biological outcomes. In this review, we will focus on illustrating that PTPs exhibit defined substrate specificity and subsequently regulate signaling pathways in a precise manner.
The PTP Superfamily
The superfamily of PTPs is characterized by a consensus signature motif represented by HC(X)5R, which defines the active site of these enzymes. Two classes of PTPs can be defined (FIGURE 1⇓). The first class is composed of classical PTPs that are defined by cysteine-based phosphotyrosine specificity, and the second class constitutes the dual-specificity phosphatases (DSPs). There are 37 classical human PTP genes that contain at least one PTP domain of ~280 amino acids. The DSPs are much larger in number, and there are 65 of these genes in the human genome. The classical PTP genes can be further subdivided into transmembrane receptor PTPs (RPTPs), or non-transmembrane PTPs, which localize to the cytoplasm (2, 4, 68). There are 12 RPTPs containing tandem PTP domains with the remainder containing a single PTP domain. The membrane-proximal PTP domain (D1) and membrane-distal PTP domain (D2) serve distinct roles. In the majority of cases, the D1 PTP domain comprises the active domain, whereas in most cases, but not all, the D2 domain serves a negative regulatory role. Although still quite controversial, evidence has been put forth to suggest that RPTPs are regulated through dimerization whereby RPTP activity is inhibited upon dimerization. However, there is also evidence against such a model of RPTP regulation, and further work in this particular area is warranted. Much like the RTKs, RPTPs utilize their diverse extracellular domains to transduce intracellular signals through binding to soluble ligands, but, in addition, RPTPs utilize their extracellular domains to mediate cell-cell and cell-matrix interactions (33, 35, 45, 73). The non-transmembrane or cytoplasmic PTPs contain a single PTP domain, and their diversity is derived through noncatalytic regulatory domains that reside either at the NH2 or COOH terminus of the PTP domain (2–3, 68). The noncatalytic domains are critical for exerting PTP substrate specificity and include one or more of the following features: 1) regulation of PTP activity, 2) directing subcellular localization, and 3) targeting PTP protein-protein interactions. Hence, the noncatalytic regions of the non-transmembrane PTPs offer a broad level of structural diversity, and together with the PTP domain, it provides a robust mechanism for substrate selection (FIGURE 2⇓).
The most diverse subgroup amongst the PTP superfamily constitutes the 65 genes encoding the DSPs (3, 9, 68). DSPs are non-transmembrane PTPs that contain a single PTP domain with an assortment of noncatalytic motifs that participate in substrate recognition. The catalytic pocket of the DSPs assumes a shallower conformation compared with the tyrosine-specific PTPs, allowing accommodation of not only phosphotyrosine but additionally phosphoserine and phosphothreonine (79). Some members of the DSPs are also capable of accommodating non-protein substrates such as phospholipids. The subgroup of DSPs that have been studied most extensively is the mitogen-activated protein kinase (MAPK) phosphatases (MKPs). The MAPKs are a subfamily of serine/threonine kinases that play major roles in regulating cellular function. The three major subgroups of the MAPKs are the extracellular signal-regulated kinases 1 and 2 (Erks), c-Jun NH2-terminal kinase (JNK), and p38 MAPK. There are 10 MKPs, all of which have the capacity to dephosphorylate the regulatory threonine and tyrosine residues on MAPK, leading to its inactivation (62). Some MKPs preferentially dephosphorylate the stress-responsive MAPKs, p38 MAPK, and JNK but not Erk, whereas others only dephosphorylate Erk (10). The selectivity of the MKPs toward the MAPKs is mediated by a noncatalytic domain on the MKPs known as the kinase interaction motif (KIM), which directs MAPK-MKP interactions (10, 52, 74). The affinity of the interaction between MAPK and the KIM dictates the selectivity of a MKP for a particular MAPK substrate (63). The KIM domain is also found in two tyrosine-specific PTPs, the striatal-enriched PTP (STEP) and the hematopoietic PTP (HePTP), both of which are capable of dephosphorylating Erk (27, 72). Again, in this instance, the KIM domain provides these tyrosine-specific PTPs with MAPK binding specificity and, hence, MAPK substrate selection.
Regulation of PTP Function
PTP function can be regulated through the control of when and where they are expressed. In addition, PTPs are posttranslationally regulated through a variety of modifications including proteolysis, phosphorylation, sumoylation, and oxidation. There has been much focus on the actions of these types of posttranslational modifications as dynamic mechanisms through which PTPs can be regulated. Recent advancements provide insight into novel modes of PTP regulation by posttranslational modifications.
Proteolysis is a common posttranslational modification that regulates PTP activity. For example, calcium is a critical initiator of protease activity, and it has been found that the calcium-activated protease, calpain, elicits cleavage of negative regulatory domains of several non-transmembrane PTPs resulting in their activation. PTP-1B, PTP-MEG, and SHP-1 are activated upon calpain-induced cleavage (23, 25, 29). In addition, several members of the receptor PTPs (e.g., LAR, RPTPσ, and RPTPγ) are subject to limited proteolysis of their extracellular domain such modifications could control receptor interactions with ligand and/or extra-cellular matrix components.
Phosphorylation is also a key regulator of PTP function. PTP-PEST, when phosphorylated on serine by protein kinase C, leads to a robust stimulation of its phosphatase activity (26). Tyrosyl phosphorylation of PTPs such as PTP-1B, SHP-1, SHP-2, and RPTPα appears to modulate the level of phosphatase activity as well as promote the assembly of protein complexes. For example, tyrosyl phosphorylation of PTP-1B has been reported to result in increased phosphatase activity (19). Whereas, tyrosyl phosphorylation of SHP-2 and RPTPα generate binding sites for protein-protein interactions with adaptor proteins such as Grb2, which functions as a platform from which to direct activation of the Ras/Erk pathway (6, 32).
PTPs are now recognized to be targets for modification by oxidation (69). Oxidation of the essential catalytic cysteine within the C(X)5R active site motif impairs the nucleophilic function of this key residue, rendering the PTP inactive. Importantly, the oxidation of the catalytic cysteine is reversible, making this modification a dynamic mode of PTP regulation (56). A number of PTPs have been found to be reversibly oxidized, and these include PTP-1B, TC-PTP, SHP-2, MKPs, and RPTPα (36, 46–47, 55). The physiological outcome of reversible PTP oxidation suggests novel modes through which PTP activity and, hence, function can be discretely controlled within precise spatial locales. Two additional posttranslational modifications have recently been reported to occur on PTPs. PTP-1B was found to undergo sumoylation in response to insulin, which led to its inactivation (18). These experiments demonstrated that sumoylation of PTP-1B can function as a negative feedback mechanism in response to insulin. This was the first example that sumoylation directly modulates PTP activity. However, it remains unclear as to the physiological significance of this modification on the function of PTP-1B in metabolic regulation. Presumably, failure to appropriately sumoylate PTP-1B following insulin stimulation would be expected to increase insulin sensitivity. More recently, acetylation of MKP-1 on lysine 57 was shown to promote the association between MKP-1 and p38 MAPK (11). Deacetylase inhibitors were found to block LPS-induced p38 MAPK activation in wild-type but not in MKP-1-deficient mice, suggesting that acetylation of MKP-1 facilitates p38 MAPK dephosphorylation (11). It still remains to be established as to what the molecular basis is for this MKP-1/p38 MAPK interaction, especially in context of the established role of the KIM domain and whether acetylation is a more general mechanism of MKP/MAPK regulation.
Physiological Signaling Specificity by PTPs
Despite the tremendous advances in PTP research, there is still the perception that PTPs function non-specifically and play largely housekeeping roles. However, there is now more than ample evidence based on structural, biochemical, and genetic studies that firmly dispel this perception. The examples cited above demonstrate that posttranslational modifications and protein-protein interactions contribute to PTP specificity. Additionally, the PTP domain itself exhibits properties of intrinsic substrate specificity. From a structural standpoint, the surface of the PTP domains are quite diverse (2, 4, 5). These observations suggest that there are likely to be significant differences in the surface electrostatic potential among the PTPs that contribute to substrate selectivity (2, 4, 5). To illustrate the specificity that exists within the PTPs, and subsequently the signaling pathways that they engage, we will compare those PTPs that share very close structural similarities but yet affect distinct physiological responses.
PTP-1B and TC-PTP: close cousins but definitely not twins
The first non-transmembrane (NT1) subfamily is composed of two PTPs, PTP-1B and T-cell PTP (TC-PTP) (FIGURE 1⇑) (3). Structurally, PTP-1B contains an NH2-terminal PTP domain and a COOH-terminus containing both an ER retention sequence and a poly-proline-rich motif. TC-PTP has two forms, one that localizes to the nucleus and another to the cytosol. Remarkably, the PTP domain of TC-PTP and PTP-1B share 71% amino acid identity (3). Yet, although TC-PTP and PTP-1B share some common targets, they are also capable of dephosphorylating distinct subsets of tyrosyl phosphorylated proteins. A number of RTKs have been identified as PTP-1B substrates, such as the epidermal growth factor receptor (EGFR), platelet-derived growth factor receptor (PDGFR), colony stimulating factor-1 receptor (CSF-1R), insulin-like growth factor-1 receptor (IGF-1R), and insulin receptor (IR) (22, 24, 31, 38, 41). Similarly, TC-PTP dephosphorylates an overlapping subset of RTK substrates that includes IR, CSF-1R, and EGFR (46, 59, 66). In contrast, TC-PTP and PTP-1B dephosphorylate similar but largely distinct sets of non-RTK substrates. For example, PTP-1B targets include the Src family kinases (SFKs) (8, 13, 43) and JAK2 (14, 28, 49, 80), whereas TC-PTP targets the SFKs (71) and JAK1 (60). These observations point to the fact that, despite their high similarity between their PTP domains, PTP-1B and TC-PTP can target different substrates.
Studies in which chimeras between PTP-1B and TC-PTP were performed provided evidence for intrinsic specificity within their PTP domains. Using PTP substrate-trapping approaches to capture tyrosyl phosphorylated PTP substrates, it has been shown that PTPs indeed interact with distinct subsets of tyrosylphosphorylated proteins (65). Interestingly, by swapping the PTP domains between PTP-1B and TC-PTP, Tiganis et al. showed that, despite the PTP domain of TC-PTP being targeted to the precise locale of endogenous PTP-1B, the TC-PTP/PTP-1B chimera was unable to form the same repertoire of PTP-substrate interactions compared with wild-type PTP-1B (66). These experiments further support the idea that the PTP domains of PTP-1B and TC-PTP exhibit unique properties that govern substrate specificity.
Insight into the physiologically important pathways that PTP-1B and TC-PTP engage in has emerged from the use of mouse genetic approaches. Mice lacking PTP-1B exhibit no obvious developmental defect but are resistant to diet-induced obesity and have enhanced insulin sensitivity due to increased levels of insulin-mediated signaling (22, 39). In contrast, mice lacking TC-PTP die shortly after birth due to severe defects in the hematopoietic system (78). These differences are likely attributed to the intrinsic PTP substrate specificity of both PTP-1B and TC-PTP in addition to their distinct tissue expression patterns and other features imparted by their noncatalytic domains. Together, these properties are likely to be sufficient to account for the unique physiological signaling effects of these closely related PTPs (FIGURE 3⇓).
SHP-1 and SHP-2: opposites attract
The SH2 domain-containing phosphatases include the second non-transmembrane group (NT2) of the PTP superfamily (FIGURE 1⇑). The SH2 domain-containing PTPs contain tandem NH2-terminal SH2 domains and a COOH-terminal PTP domain. Within the PTP domain, SHP-1 and SHP-2 share 61% sequence identity and 55% sequence identity overall (50). SHP-1 is expressed predominately in the hematopoietic compartment, whereas SHP-2 is expressed ubiquitously. The SH2 domains of SHP-1 and SHP-2 target them to specific phosphotyrosyl-containing proteins within a sequence-specific context (61). Despite the seemingly high structural similarity, SHP-1 and SHP-2 could not be more different in their function; SHP-1 negatively regulates, whereas SHP-2 is generally a positive regulator of cell signaling (FIGURE 3⇑).
A negative signaling role for SHP-1 was demonstrated when it was discovered that mutations in SHP-1 cause the autosomal recessive disorder in mice called motheaten (me), a hematological disease in which mice exhibit a severe combined immunodeficiency syndrome (81). Indeed, the identification of several SHP-1 substrates supports the notion that SHP-1 negatively regulates hematopoietic signaling. SHP-1 has been shown to dephosphorylate the CSF-1 receptor (67) as well as intracellular signaling molecules known to positively regulate hematopoietic signaling such as the SFKs (16) and proteins that function as assembling platforms for molecules such as the paired immunoglobulin-like receptor B (PIR-B) and CD72 (67, 76). There have been cases where SHP-1 has been suggested to function as a negative regulator of cell signaling in non-hematopoietic tissues. For example, SHP-1 has been shown to dephosphorylate the carcinoembryonic-antigen-related cell adhesion molecule-1 and the insulin receptor in the liver (21). These effects are proposed to result in the impairment of glucose homeostasis in the motheaten mouse (21).
In contrast to SHP-1, SHP-2 signals positively in virtually all cases, although there have been a few select reports where it plays a negative regulatory role (82). The differential binding specificity of the SH2 domains for SHP-2 compared with SHP-1 likely explains, in part, its distinct signaling effects to that of SHP-1 (61). SHP-2 interacts, via its SH2 domains, with the EGFR and PDGFR directly and/or couples indirectly to other RTKs through binding to adaptor proteins (51). Unlike SHP-1, SHP-2 positively stimulates the Ras/Erk pathway (51), clearly indicating that SHP-1 and SHP-2 must dephosphorylate distinct sets of substrates. Moreover, the positive effects SHP-2 has on the Ras/Erk pathway has implicated it as a potential candidate in the development of cancer (12). Interestingly, domain-swapping experiments between SHP-1 and SHP-2 demonstrate that the PTP domain of SHP-1 cannot recapitulate the function of the PTP domain for SHP-2; the opposite is also the case (53). Hence, the PTP domains of SHP-1 and SHP-2 contain intrinsic specificity for substrates that define their effects on downstream signaling.
A number of SHP-2 substrates have been identified, although only a select few provide direct mechanistic insight into the basis for SHP-2's positive signaling effects, and this area still remains quite controversial. Some of these substrates include the EGFR, whose dephosphorylation at Y992 serves to prevent p120RasGAP from being recruited to a complex to inactivate Ras (1). Our group has demonstrated a similar mechanism of SHP-2 action in muscle cells where SHP-2 prevents the inactivation of RhoA by dephosphorylating p190b RhoGAP (40). Hence, site-specific EGFR dephosphorylation or direct dephosphorylation of a RasGAP by SHP-2 promotes small GTPase activation. SHP-2 also signals positively to Erk through its ability to control SFK activation (83). Thus, in contrast to SHP-1, SHP-2 assembles with distinct protein complexes and dephosphorylates targets that are negatively regulated by tyrosyl phosphorylation. Unlike SHP-1, where disruption of its function leads to hematological disease (70), loss of SHP-2 function in mice results in embryonic lethality (58, 77). An even more striking example of the diametrically opposite functions that SHP-1 and SHP-2 display has emerged through the discovery that mutations in the human PTPN11 gene, which encodes for SHP-2, causes ~50% of Noonan syndrome cases (64). Noonan syndrome is an autosomal-dominant disorder that results in cardiovascular defects, musculoskeletal anomalies, and increased risk of leukemia (64). What is striking about the PTPN11 mutations that cause Noonan syndrome is that they map to regions of SHP-2 that result in its constitutive activation (64). Enhanced SHP-2 phosphatase activity is thought to give rise to Noonan syndrome through constitutive stimulation of the Ras/Erk pathway (7). However, it is not clear whether the Ras/Erk pathway alone or whether additional targets of SHP-2-associated Noonan syndrome mutations collaborate with Erk to manifest the entire repertoire of the disease. Regardless, what is evident is that SHP-2 plays a dramatically distinct signaling role in both physiological and pathophysiological contexts compared with SHP-1.
MKP conundrum: overlapping MAPK substrates distinct signaling fates
The MKPs represent a provocative case study for understanding the physiological signaling specificity of PTPs. Because the 10 members of the MKP family all dephosphorylate Erk, p38 MAPK, and JNK, it was initially perceived that the MKPs would have redundant functions. The first knockout phenotype of an MKP was that of MKP-1, and the initial assessment of this phenotype supported the idea of redundancy (20). Despite the fact that all the MKPs share a common set of MAPK substrates, the complexity of their regulation at the transcriptional and posttranslational level is broad enough that these enzymes show stark differences in their physiological actions (15, 17, 42, 75, 84). The emergence of genetic data now argue strongly against the initial perception of redundancy among the MKPs (Table 1⇓), and compelling evidence for physiological signaling specificity for these enzymes has emerged.
MKP-1, the first MKP identified, is a nuclear localized immediate-early gene that dephosphorylates p38 MAPK and JNK comparably, and Erk to a lesser extent (54). Although initial efforts analyzing MKP-1-deficient mice revealed that there was no obvious phenotype (20), subsequent analysis of these mice in response to LPS indicated that MKP-1 functions as a major negative regulator of the innate immune response (15, 30, 57, 85). Mice lacking MKP-1 were sensitive to LPS-induced endotoxemia, and macrophages isolated from these mice exhibited dramatically enhanced p38 MAPK and JNK, but not Erk, activity in response to LPS (15, 30, 57, 85). MKP-1-deficient mice are also resistant to diet-induced obesity (75). Surprisingly, despite being lean, MKP-1-deficient mice still succumb to the effects of insulin resistance when fed a high-fat diet. These observations were reconciled by demonstrating that MKP-1 was restricted to dephosphorylation of the nuclear pool of MAPKs, whereas the cytoplasmic pool of MAPKs that influenced insulin signaling were subject to separate regulatory mechanisms and the deleterious effects of high-fat feeding (75). These results highlight an important mechanism through which the MKPs exert signaling specificity through the dephosphorylation of discrete pools of MAPKs (37) (FIGURE 4⇓).
Other MKPs that have been knocked out show quite remarkable and distinct phenotypes (Table 1⇑). For example, MKP-3-deficient mice that survive weaning show skeletal dwarfism, cryaniosynostosis, and developmental defects, which is consistent with MKP-3 being a negative regulator of the Erk pathway downstream of FGF receptor signaling (42). However, these differences have not been observed by others (44). On the other hand, MKP-4 (DUSP9), which, like MKP-3 (DUSP6), predominantly dephosphorylates Erk (48), when deleted in mice results in embryonic lethality as a result of a placental defect (17). The knockout of MKP-5, as for MKP-1, exhibits no remarkable phenotype. However, MKP-5-deficient mice show increased JNK activity in T-cells but, surprisingly, fail to proliferate in response to anti-CD3 stimulation (84). These authors demonstrated that MKP-5-deficient mice were enhanced in their sensitivity to the innate immune response and were protected from the development of autoimmune disease (84). Hence, although MKP-5 and MKP-1 both target JNK, the physiological outcome of MKP-5 deletion suggests that MKP-5 and MKP-1 have distinct regulatory roles even within the immune system. Finally, PAC-1 (DUSP2)-deficient mice also develop normally but are protected from arthritis, similar to MKP-5-deficient mice (34). However, the signaling mechanisms of Pac-1 regulation is complex since, although there is enhanced JNK1 activity, p38 MAPK and Erk are paradoxically decreased (34). These results suggest that the enhanced activity of JNK influences p38 MAPK/Erk activities in a cross-talk type of manner (34). Collectively, the observations derived from the various MKP-deficient mouse models exemplify the physiological signaling specificity of these PTPs within the intact organism despite their remarkable selectivity toward the MAPKs. These observations suggest that there are likely to be additional levels of regulation among the MKPs that have yet to be fully recognized.
Future Perspectives
There is clearly a substantial body of data from which an unequivocal conclusion can be made to support the notion that PTPs are highly specific. The features that confer PTP specificity stem from the fact that PTPs are structurally diverse, are subject to multiple levels of regulation, and exhibit intrinsic substrate specificity within their catalytic domains. One challenge that still remains is to define the substrates that the PTPs dephosphorylate. This information will provide important insight into the fundamental mechanisms involved in PTP-mediated signaling. Nevertheless, we are now appreciating that PTPs are key players in a multitude of physiological processes. In some cases, the dysfunctional actions of PTPs underlie the molecular basis for the cause of certain human diseases. This suggests that PTPs represent an untapped source for the development of therapeutics for the treatment of human disease. The challenge will be to continue to uncover the physiological roles of the PTPs and to identify the structural determinants that dictate their specificity. With this knowledge, the future of the PTPs as coveted therapeutic targets will begin to be realized.
We apologize to our many colleagues whose contributions to this area of research was not discussed due to space limitations.
A. M. Bennett was supported by National Institute of Health Grants AR-046524, DK-075776, and DK-057751.
- Copyright © 2009 the American Physiological Society


text:
You are here
Futures strength buying corn acres from soybeans
Corn Fundamentals: Bullish fundamentals include strong demand both
domestically for feed use and for exports. Investment capital continues to
pour into corn for ethanol. Also, over fear of inflation, based on the weaker dollar, there is a growing interest with those wanting to own tangible
products such as the grains. Bearish signals are big domestic stocks of old crop corn. Bullish
factors for new crop Dec futures are USDA's projected end stocks for the
2006/07 marketing year.
Because of the futures' reaction to the USDA WASDE
report, talk is already circulating, given a average growing season, we may
have likely witnessed USDA's smallest 2006/07 end stocks in Friday's report. Plus, futures strength is said to be buying additional corn acres away from
For this week, we see a build up of soil moisture for the east
Corn Belt and net drying for the west Corn Belt. For next week, we see just the opposite scenario for both belts.
Export Sales: USDA increased its 2005/06 old crop corn export target to
2.025 from 1.95 bil bu. Per the latest sales data for week ending May 4th,
export sales are running 11% higher than yr ago levels. The present pace
suggest a final sales level of 2.080 bil bu. Our research suggest old crop
export sales drop off perceptibly in late June-early July. This is
important to know if you are planning on holding and then flat pricing old
crop 2005 grain. USDA set new crop export sales at 2.15 bil bu. USDA did
increase corn exports to China for old crop corn from 100,000 tonnes (4 mil
bu) to 290,000 tonnes (11 mil bu). However they estimate 2006/07 new crop
export sales to China back to 100,000 tonnes, in a word, disappointing.
Ethanol Production: USDA left 2005/06 marketing year corn consumption for
ethanol at 1.6 bil bu but catapulted new crop corn consumption to 2.15 bil
bu or 34.4% higher. Based on 78 mil acres planted from the March 31st
Planting Intentions report, Allendale suggest a level of 1.92 bil bu or
more of a traditional 20% yr to yr increase. Transporting the finished
ethanol product of ethanol to refineries for blending purposes remains a
very serious barrier for producers.
Quarterly Corn Stocks: March 1 Quarterly corn stocks on and off farm of
6.987 bil bu suggest June 1 quarterly corn stocks could come in at 4.692
bil bu which would be 37% higher than the three yr ave and 32% higher vs
the five yr ave for 3rd quarter stocks.
Season Ave Farm Price: For old crop corn, USDA left the season ave farm
price range unchanged from April's est of $1.95 to $2.05/bushel. For new
crop USDA has increased the season ave farm price to $2.25 to $2.65/bu.
Looks as though USDA is working on as little if any LDP for the fall of
End Stocks to Use: Old crop domestic end stocks to use are 20.2% vs last
years 19.8%. We would have to venture back to 1992 to find a larger value
which was 24.9% with a stocks level of 2.113 bil bu vs the present 2.226
bil bu. Global stocks to use are 17%. Since 1980 only 2003 were tighter at
14.3%. New crop end stocks to use are projected at 9.8% when using 78 mil
acres planted. If we plug in additional acres of 1.8 mil, taken primarily
away from soybeans, the end stocks to use increase to 11.9% or 1.384 bil
bu. Projected world end stocks to use for 2006/07 are 11.6%, which would be
a record, even tighter than 2003's 14.3%.
Dec Corn Futures: suggest a Dec futures high of 2800 near term and
correction to 2200 before the summer season could take futures back up to
2800 with a maximum high of 3000 under extreme conditions. Our fall low
suggest a price of 2300.
Dec Corn Five Year Ave: The most recent five yr historical ave suggest Dec
corn peaks now and grinds lower into late May. A retest of the April high
has been noted in early June , consolidates July through the middle of
September and then slides into the fall harvest.
Five Year Ave Cash Price: The five year ave cash price for corn for the
month of April $2.14, month of May $2.14 and month of July $2.03.
Bean-Corn Ratio: The CBOT floor trade perception for corn acres to steal
from soybean acres needs a bean-corn ratio of 2.19 to 1. At the close of
business for the planting intentions report the ratio was 2.25 to 1.
Friday's closing ratio is 2.24 to 1, down .13 vs last weeks close.
Corn Technicals: Two weeks ago, Friday's July futures close 2404, last Friday's futures close
2582. Our short term Moving Average indicators are 2420-2430 and 2450. Two weeks ago, Fridays Dec futures close 2640, last Friday's futures close 2816. Our short term
Moving Average indicators are 2670-2670 and 2680.
Trade Position: We are long old futures based on the funds interest in corn
based ethanol. Our objective for the long position has been and remains
2600. Friday's July futures high of 2600 did not allow us to reach the
objective until futures trade through 2600. Our long objective for Dec corn
futures was reached by mid-session Friday.
Soybean Fundamentals: It''s difficult to accept soybean futures closing
lower, that is until you glean through USDA's WASDE report and witness some
hefty end stocks estimates. Remember, USDA's WASDE report is based on the
Planting Intentions report released March 31st and is likely to be adjusted
lower when the June 30th Planted Acreage report is released. Brazil did
announce it will include soybeans in its government buying program and
should be enough to remove road and rail blockades. It looks as though
foreign investors which have a stake in exporting soybeans and it products,
convinced the Brazilian gov't to get serious about supporting the farmers
to ensure a steady flow of soybeans and to help the investors bottom line.
New Crop Sales: We added 20% more new crop hedges as outlined in our Hedge
Advice page. We do not recommend, as of yet, to cover with a call as we have
already done for new crop corn hedges.
Soybean Crush: Profit margins for crushing soybeans are at levels last
witnessed in the summer of 2004. Margins are approaching 80 cents when full
production mode is typically held in a range of 60 to 75 cents. Crushers
appear to be wading in profit and there are plenty of old crop supplies to
be had. See the quarterly stocks section below.
Export Sales: USDA increased left 2005/06 old crop soybeans export target
of 900 mil bu unchanged. Per the latest sales data for week ending May 4th,
export sales are running 21% lower than yr ago levels. The present pace
suggest a final sales level of 882 mil bu. Our research suggest old crop
export sales drop off perceptibly in late June-early July. This is
important to know if you are planning on holding and then flat pricing old
crop. USDA set new crop export sales at 1.09 bil bu.
Season Ave Farm Price: For old crop beans, USDA left the season ave farm
price unchanged from April's est of $5.65/bushel. For new crop, USDA has
decreased the season ave farm price to $5.60/bu and is using a range of
$5.10 to $6.10.
Quarterly Stocks: March 1 Quarterly stocks on and off farm of 1.669 bil bu
are a record and suggest June 1 quarterly stocks could come in at 1.077 bil
bushels. If realized, this would be 89% higher than the three yr ave and 73% higher vs the
five yr ave for 3rd quarter stocks.
End Stocks to Use: Based on the USDA's March 31st planting intentions
report, if farmers follow through with their intentions, projected end
stocks to use for 2006/07 is 21.7% vs the 2005/06 level of 20.3%. USDA
estimates new crop end stocks at 650 mil bu. This compares to old crop end
stks est of 565 mb. Since 1980, the highest stocks level close to USDA's 650
mil bu is its 2005/06 565 mil bu and then back to 1985's 536 mil bu.
Price Projections: Allendale price projections for Nov futures are
estimates to trade in a range of 5500 low to 6500 high throughout planting,
into the growing season and into the harvest.
Nov Soybeans Five Year Ave: The most recent five yr historical ave suggest
Nov futures consolidate in the months of April and May before walking
higher into June and July. After hitting its historical peak in early July,
futures have been known to sell off into October.
Five Year Ave Cash Price: The five year ave cash price for soybeans for the
month of April is $6.03, month of May $6.16, month of June $6.22, month of
July $6.25 and month of August $5.81. Price may not be as important as the
trend and timing.
Soybean Technicals: Two weeks ago, Friday's July futures close 6064, last Friday's futures
closed at 6130. Our short term Moving Average indicators are 6030-6000 and
5980. Two weeks ago, Friday's Nov futures closed at 6252, last Friday's futures closed at 6320. Our
short term Moving Average indicators are 6250-6250 and 6170, key support.
Trade Position: Because of the amount of calendar time
remaining to plant soybeans, a poor Friday close near its lows of the day,
and Brazil's gov't decision to support its farmers, we are willing to stop
ourselves into short positions at lower levels. The huge amount of longs
from the funds has created little elbow room and may need to rid the room
of some weak longs. There is a bit of a ground swell from several of the
capital investment firms suggesting a "parabolic" in commodities such as
the metals and energies, both corn for ethanol and soybeans for bio diesel
close attachment to the energy markets could experience weakness if those
outside influential futures markets experience a cleansing.
Wheat Fundamentals: If there is a grain market which is justifiable in its
level of futures existence based on supply fundamentals it is likely wheat.
USDA revealed very serious low levels of production as viewed near the
bottom of our Midsession Comments page. Be aware it is not uncommon for the
trade to transition away from production driven to demand driven.
End Stocks to Use: Domestic end stocks to use are est at 21.6% vs 2003's
tight levels of 23.2%. World end stocks are thin, primarily because of the
smaller production in the USA. At an estimated 17.7%, they are tighter than
2003's 18.9% and at no time dating back to 1980 have been as tight as they
are presently estimated. With the potential for record low end stocks to
use globally for wheat and corn simultaneously at least into the first half
of 2006, futures prices are anticipated to stay firm until world wheat
producers respond to the high futures levels, demand is restricted because
of the high prices and or the energy markets collapse.
Season Ave Farm Price: for old crop wheat USDA left the season ave farm
price relatively unchanged from April's est of $3.40/bushel. For new crop
USDA has the season ave farm price range est at $3.50 to $4.10/bu for an
ave of $3.80/bu.
Wheat Technicals: Key custom moving averages for July wheat futures are as follows: CBOT's SRWW ='s 3910-3780 & 3700, Last Friday's close 4014, KCBT's HRWW
='s 4720-4580 & 4510, tonights close 4812, and MGEX Spring Wheat ='s
4330-4320 & 4310, last Friday's close 4592.
Export Sales: If there is an immediate sign of suppressed demand because of
high prices, it might be the old crop export target. USDA did drop exports
from 1.015 bil bu to 1 bil. New crop exports are dialed in at 900 mil bu.
Of the potential production of 1.873 bil bu, exports are expected to
account for 48%. This is not a uncommon percentage for USDA to use. World
competitors could take USA market share if prices stay lofty too long
within the USA. Ask yourself, when is the last time the USA made a big
package sale since prices crossed over $4 for KCBT and $3.50 for CBOT?
July Wheat Futures: Seasonally, 5 yr ave July futures hit its peak in the
month of April, a aslide into the month of May, a correction of 50% into June and then a slide into new lows in the month of July.
Dec Wheat Futures: seasonally 5 yr ave Dec futures are near its lows in
late April, stage a small rally in the month of May, work into new lows by
July and then rally to its highs into Sept before falling sharply to its
lows in Oct.
Trade Position: Our short calls risk levels were triggered last Friday. The trend
for corn, beans and wheat, remains up and until futures experience at least
two back to back closes below our key custom moving averages, traders
attitudes are expected to remain bullish.
Lean Hogs: Steady to lower prices were seen in the CME pork pits on Friday. The
wholesale pork trade is slowly accepting the idea post Memorial Day demand
for pork may fall more than market ready hog numbers. Cash hogs traded
mostly steady today. Packers are trying to match up available hog numbers
with demand for pork. For right now, they are more concerned about
declining pork values than putting together a full kill for next week.
Therefore they are keeping kill plans a little tighter than perhaps they
could be. Overall, we still view the seasonal top ideas as valid. Our main
hedge objective is not to pick exact tops or bottoms but to market around
the seasonal peak at respectable price levels. We still feel the futures
trend will change from up to steady/lower soon and would work on
speculative trades accordingly. For hedging we are now 75% sold through
Live Cattle: Active cash cattle trade developed at $78 and $78.50 in the
central and southern plains. That was steady with two weeks ago and as we
expected. One interesting thing to note about Friday's trade was the strong
comeback from early morning losses for the feeders. Higher corn prices off
the open did scare feeder cattle traders. Higher feed costs could
potentially cause cattle feeders to stop visiting the sale barn for a new
load. We hate to say it, but if losing $100 per head on finished cattle
right now is not going to deter you from buying new feeders, a dime rally
in corn certainly won't either. On the fat cattle end, we can note both June
and August, live cattle futures broke through the resistance levels. These big gains in open interest noted last week have shown
futures are gathering quite a bit of interest.
On the charts, fed cattle
futures are not looking too bad. We are neutral on summer month futures but
today's activity could shift that to neutral supportive. For hedges there
is no reason to add any to current levels.
Allendale is registered with the CFTC and NFA and is a member of the NIBA.
The bottom line is we are a regulated firm which can be extremely important
in this day and age.
Corn Fundamentals: Bullish fundamentals include strong demand both domestically for feed use and for exports. Investment capital continues to pour into corn for ethanol. Also, over fear of inflation, based on the weaker dollar, there is a growing interest with those wanting to own tangible products such as the grains. Bearish signals are big domestic stocks of old crop corn. Bullish factors for new crop Dec futures are USDA's projected end stocks for the 2006/07 marketing year.


text:
Winter cleared of assaulting Luke Adams
A 20-year-old Perth man has been found not guilty of causing grievous bodily harm to former WAFL player Luke Adams.
A District Court jury deliberated for two hours before acquitting Dylan Winter of assaulting Mr Adams in a drunken fight in Northbridge in May last year.
Mr Adams suffered a fractured skull and a brain injury when he hit his head on the ground.
Mr Winter denied any wrongdoing maintaining that he acted in self defence and that Mr Adams was the aggressor.
Members of Mr Winter's family cried as the verdict was delivered.
Mr Adams was not in court.
Topics: courts-and-trials, perth-6000
First posted


text:
All Android applications categories
Bridal wedding gowns collection for your wedding day! Fantastic long and short wedding gown for your wedding day. We made a wonderful collection of brilliant bridal wedding gowns or affordable wedding gowns suitable for every bride. Make your marriage unique and download our amazing designer wedding gowns app. This is a collection of the best unique lazaro wedding gowns, vera wang wedding gowns and alfred angelo wedding gowns, we have collected for you. We have lot of beautiful modest wedding gowns, discount and cheap wedding gowns, couture wedding gowns, vintage wedding gowns, lace wedding gowns.
Download our wedding collection such as disney wedding gowns, modest wedding gowns, wedding gowns with sleeves, and chose one gown for you. Finding the perfect bridal wedding gown is not so easy, so we offer you a little help with our unique wedding gowns 2012, with our mobile wedding application.
- This app may show notification and icon ads. To opt out, go to http://www.airpush.com/optout and/or http://opt.leadbolt.com
- For more information, and for any question about us and our apps please contact us via e-mail firstname.lastname@example.com
If you see anything you like you can share it with your friends on Facebook with a click of a button.
Note, all material shown in this app was gathered from Google Images, Twitter, YouTube for you.
Tags: puzzle de robe de mariée , wedding photos gallery , gallerie de photo de robe de mariage gratuit , 新娘禮服是短期的,那麼
from 43 reviews
Download Wedding Gowns Gallery
Free - 1.0 - 3M
Sorry ...
This app is no longer available.Explore Android
Share this app


text:
New 2017 Ford Transit Connect XL
- MAKE:Ford
- MODEL:Transit Connect
- BODY TYPE:Van
- ENGINE:2.5L I4 iVCT
- TRANS:Automatic
- LOCATION:Livermore
- EXT COLOR:Frozen White
- INT COLOR:Charcoal Black
- MPG:20 city / 27 hwy
*Please note: we update our inventory daily. Please check with dealer to confirm vehicle availability.
Sellers Comments
Factory MSRP: $25465 $3082 off MSRP!
Looking to find out more? We invite you to stop in and see us at Livermore Ford of Livermore where we can keep the conversation going. We can be reached in a variety of ways; either over the phone through our website or of course in person. Our team loves getting to know drivers in greater Fremont Dublin Pleasanton and San Ramon and we strive to give you the most enjoyable experience possible. Feel free to swing by during regular business hours and we can get the ball rolling and discuss all your car options.
2017 Ford Transit Connect XL 2.5L I4 iVCT Frozen White 27/20 Highway/City MPG
* ALG Residual Value Awards Price includes: $2500 - Retail Customer Cash. Exp. 01/02/2018
- No information on options available.
- No information on specs available.
Vehicle Location
Livermore Ford Lincoln
2266 Kittyhawk Road
Livermore, California 94551


text:
WATCH: Demba Ba's kung-fu kick on Guangzhou Evergrande defender
Shanghai Shenhua forward Demba Ba accidentally kung-fu kicked Guangzhou Evergrande defender Feng Xiaoting during their meet in a Chinese Super League's 2-2 draw.
The former Chelsea player raised his leg to fight for a high ball but he mistimed his jump and landed his boot on the face of Feng Xiaoting.
Players from both teams surrounded the Senegalese star, who was only booked instead of being sent off for his dangerous play.
Following the incident, it was seen that the 30-year-old apologised to his opponent and tred to explain to everybody that the tackle wasn't intentional.
Watch the video below:
Prev : Seven biggest foreign signings in Thailand this summer
Next : Shanghai SIPG face testing month in pursuit of history
Next : Shanghai SIPG face testing month in pursuit of history


text:
Aubrey Grace Koch
Aubrey Grace Koch was born on February 2, 2011 to Doug and Denise Koch of Monticello. Aubrey Grace weighed 6 lbs. 7 oz. and was 18" long. Grandparents are Ron and Cheryl Kenyon of Alberta and Steve and Mary Koch of Chokio. Great grandparents are Mary I. Anderson of Morris and Burnys Koch of Chokio.


text:
The second of one, top-seeded team will be on hand to help his squad when it throws its first rocks in the Canola Junior Men's Provincial Championship that starts at the West Kildonan Curling Club on Thursday morning.
But Derek Oryniak will not be able to finish the job for Kyle Doering's fourth-ranked West Kildonan rink.
Oryniak, you see, will head off to Innsbruck, Austria, on Sunday, where he will play for Canada in the mixed curling event of the inaugural Winter Youth Olympic Games.
"It's tough but, you can't really complain too much because it's an experience of a lifetime going to the Youth Olympics," Oryniak said after practice Wednesday. "At the same time, I feel a little bad about letting down my team here. But, they understand and they're pretty good about it."
Kyle Kurz, who has played and practised with the team all year, will return from Mexico to replace Oryniak on Sunday, the last day of the round robin and first day of the playoff round.
"That's going to be tough," said Doering, who skipped the same squad to the bronze medal at the Canada Winter Games last year. "We're so used to playing with Derek. He's a great player but we've got Kyle Kurz … Hopefully, he'll be ready to go when he comes back."
Oryniak, 17, was one four curlers selected for the mixed team from across Canada.
"All the kids going (to the Games) had the opportunity to submit an application," said Oryniak, an honour-roll student at Miles Mac. "You had to write an essay, submit your school marks, extracurricular activities like volunteer work and stuff like that. They took that into account and they looked at your play at the Canada Games, and that's how they chose the four athletes."
The Grade 12 student also plays for the school hockey, golf and cross-country teams, plays badminton and runs the half-marathon.
This has already been a whirlwind for him since those Games.
"I travelled a lot with my Youth team all over the country," said Oryniak, who will play for P.E.I.'s Emily Gray. "We met in Regina, Edmonton, Ottawa, Brandon and Halifax. So, I got to know them really well over that time and we got to travel all over the country just to curl."
Fort Rouge's former champion Joey Witherspoon, who beat Doering in a semifinal last year, is the No. 1 seed.
"West K's our home club so we should know the ice," said Doering, 16, also supported by third Colton Lott and Lucas Van Den Bosch. "Last year, we had a really good run in the provincials so hopefully, we got experience from that. The same with the Canada Games, we can take that into this event."
BRIDESMAIDS: Just call them Bridesmaids. Victoria's Alyssa Vandepoele and Kate Cameron have combined to lose the last three provincial junior women's finals. Vandepoele lost to Kaitlyn Lawes three years ago and Breanne Meakin last year. Cameron, who lost to Meakin in-between, asked Vandepoele to join her this season, and their team was named the No. 1 seed for this year's provincials that start Thursday in Minnedosa.
"I'd say it's a great learning experience for me as well as Kate," Vandepeole said from Minnedosa. "I don't know if I believe that third time's a charm or anything like that.
"But I'm curling because I love it, not because I need to win."
Vandepoele, 19, calls the game while Cameron throws the last brick, with Abby Ackland and Sheyna Andries on the front end.


text:
Hi all,
First time poster here...I've enjoyed browsing the site and have found a lot of good info, but haven't seen anything specifically regarding my question.
My son and I have decided to keep and preserve some of the larger turtle shells (snapper)that we have accumulated this season. All fleshing has been done using the borax treatment, but they still have a strong odor to them.
I'll revisit the site often and if there is ever something I can contribute to the site, I will do so.
Thanks for any help,
Return to Reptile Taxidermy Category Menu
If they still smell, then you left meat behind. Did you remove the bridgework containg the spine and all the nerves and blood vesseld inside along the center of the upper shell? Also along the edge where you take them apart, there is a lot of meat under the overhang on each side. Double check!
[quote]bridgework containg the spine and all the nerves and blood vesseld inside along the center of the upper shell[/quote]
Does this mean removing the bone structure on the top of the shell? and if so..will that diminish the structural integrity of the shell?


text:
Charters vs. public schools: Behind the numbers
May 24, 2010
The Washington Post
Charters vs. public schools: Behind the numbers
By Valerie Strauss
Charter school advocates often like to say that many of these schools do a better job than nearby public schools with the same population of students.
That, in fact, is what writer Steven Brill says about two schools--one public charter and the other part of the New York City School system--in an article in today's New York Times magazine entitled "The Teachers' Unions' Last Stand."
The article is long, and says a number of things with which I could argue but won't here. What I will do, though, is point out the very real differences between two school populations that Brill says are the same.
This is important, because, as we all know, it isn't fair to compare apples and oranges and pretend the comparison is between two pieces of the same fruit.


text:
MONTREAL -- Danny Maciocia gathered his players prior to a closed practice at an indoor soccer facility yesterday.
"We have a lot of interesting individual stories on this team, guys who weren't wanted by other teams, Canadian players who weren't drafted, a non-import middle linebacker you aren't supposed to be able to have in the CFL, a non-import tailback."
Maciocia was going around the room and reminding each Eskimo of their own stories.
"I told them that here we are, challenging to get into the Grey Cup with a chance here to make history."
In Montreal, Maciocia, for whom Much Maligned might as well be his middle name, would be the biggest story of them all if the Eskimos were to get to the Grey Cup where he grew up eight minutes away from Olympic Stadium.
If the Eskimos lose the East Division final today vs. the Alouettes (1 p.m., TSN/RDS), people will be back on the Maciocia's-gotta-go kick.
If he wins, he'll be the same great story he was in 2005 when he became the first Eskimos coach to win three playoff games on the road, including a Grey Cup.
Except it's here, in his hometown.
"I'm sure this is going to be a pretty emotional game for Danny," said CEO Rick LeLacheur who believed in the little guy and not only kept him as coach but promoted him to head of football operations so Maciocia could, for the first time, pick the groceries to make the meal.
"Danny worked his butt off. He made a lot of progress and we're not looking back now. We have a real good foundation and there's sure not many people who thought we'd be here, especially when we lost Jason Tucker, Dan Comiskey and Fred Perry to the nine-game injury list at the start of the season."
Having the support of QB Ricky Ray has gone a long way.
"When you miss the playoffs for the first time after 34 years, that upset a lot of people," said Ray. "Fortunately, we had people who recognized that Danny is a good football coach. He has a great knowledge of the game and a great way of dealing with players. They understood that."
Ed Hervey, now a scout with the team, said it's been lost on a lot of people what Maciocia has accomplished this year.
"He turned it around and is now one step from the Grey Cup. The team is headed in the right direction again. But I understand. Two years out of the playoffs is an eternity in Edmonton ... all the fan wants is that the team be competitive, be in the playoffs and have a chance to be in the Grey Cup every year because that's what the Edmonton Eskimos are all about."
And here they are, with with Danny Maciocia still the coach, with that chance, today.


text:
New firefighter
As featured on
CHATHAM – The Borough Council accepted a $100,000 donation from the Chatham Athletic Foundat…
Post a comment as
Watch this discussion. Stop watching this discussion.
(0) comments
Welcome to the discussion.
Be Yourself. We do not accept and will not approve
anonymous comments. If your username is not your name, please sign
your posts as you would a letter to the editor with your full name
and hometown.
Keep it Clean. Please avoid obscene, vulgar, lewd, racist or sexually-oriented language.
Don't Threaten. Threats of harming another person will not be tolerated.
Be Truthful. Don't knowingly lie about anyone or anything.
Be Nice. No racism, sexism or any sort of -ism that is degrading to another person.
Be Proactive. Use the 'Report' link on each comment to let us know of abusive posts.
Share with Us. We'd love to hear eyewitness accounts, the history behind an article.
Featured Businesses
Find a local business
Upcoming Events
Nov 20
Nov 20
Nov 20
Nov 20
Nov 20
Nov 20
Nov 20
Nov 20
Latest News
- (VIDEO) Action! Clinton hosts first River Town Film Festival
- Thrift Barns fund local charities
- Noted magicians to perform in Boonton on Dec. 1
- Fete holidays in Boonton on Dec. 1
- Frigid weather doesn't deter vols from cleaning Rockaway River
- (VIDEO) Morris Hills fetes 'Alice in Wonderland'
- ShopRite, school board honor Montville High "Stars"
- Madison Rotary will host two-part series on challenges of Pacific Rim
Most Popular
- Flynn to head Morristown wrestling program
- Police: Confused text message led to false alarm of active shooter in Warren
- Peapack-Gladstone police chief to retire
- Lance, Frelinghuysen vote no on tax bill
- Unlocked BMW stolen from Bernardsville is recovered
- 1 injured in Randolph house fire
- Democrats' shocker rewrote Bernardsville history
- Bedminster police officer faces possible termination
- Roxbury pursues progress on two vacant businesses
- Harding family's fundraising for medical service dogs pays off; 'Yazzie' arrives in style Friday
- EDITORIAL: Traces of racism (5)
- LETTER: Incumbents have provided 'excellent leadership' in Mount Olive (2)
- LETTER: Issues facing Madison demand balance, debate on council (2)
- Yates, Modi re-elected in Harding Township (2)
- LETTER: 'Welcoming' Resolution is contradictory and confusing (2)
- Democrats win stunner in Bernardsville (2)
- Democratic candidates criticize GOP mailer in Chatham Township Committee race (2)
- (VIDEO) Pitney subdivision approved in Mendham Township (1)
- LETTER: Guadagno for governor is the only sane choice for New Jersey (1)
- LETTER: Deadly opioid crisis growing in Mount Olive and elsewhere (1)


text:
Masters of Morris share styles at village carnival
8:30am Monday 7th July 2014
8:30am Monday 7th July 2014
THE annual festivities of the Eynsham Carnival took over the village centre on Saturday.
The event saw dancing, craft stalls and a parade, as well as live music performances and even a llama show-jumping display.
Eynsham Carnival Queen 15-year-old Rebecca Singleton waves during the parade.
Eynsham resident Jane Stephenson attended with her Morris group Armaleggan to join Eynsham Morris in a showcase of different styles.
The 38-year-old said: "We were Eynsham Morris's guests, which was a real privilege. We were showing our two different styles of Morris dancing.
"Eynsham do Cotswold Morris and we do Border Morris. It was really interesting to see them done together."
Ms Stephenson said she joined Armaleggan three years ago but only moved to the village, from Cumnor, one year ago.
She said: "It was nice to be dancing within my community for the first time."
Darth Vader makes an appearance.
Alongside the usual displays, including a motorcycle club stall, there was an open mic competition for the first time. For details, visit eynshamcarnival. com.
Our top stories
© Copyright 2001-2017 Newsquest Media Group


text:
Royce Freeman and Thomas Tyner are great talents with a dazzling futures, but their backfield mate Byron Marshall is almost an after thought to some Oregon fans despite rushing for 1038 yards last season and 1484 in his two-year Duck career.
Marshall averaged 6.2 yards a carry in 2014 with 14 touchdowns. He put together a streak of five straight 100-yard games that included 192 against Washington State and 133 versus UCLA.
Yet when many fans talk about the upcoming season they start with the ascendance of Tyner or the fabulous potential of Freeman. Marshall running over, around and through people, often unspectacularly following his blocks or smoothly taking a pass out of the backfield, just doesn't have the same panache.
People forget that the junior from San Jose was the West Coast's #1 running back prospect the year he came out, a 4-star recruit. He doesn't have Tyner's dazzling speed, but he's not slow. Marshall has good ball security and vision. He's a patient runner who lets things develop, and he's learned to be more decisive. An injury late in the year cost him a run at 1200-1300 yards, one that might have earned him more individual credit.
The great thing about Marshall is that he hasn't gotten caught up in the comparisons or recognition. Like Marcus Mariota he's a football player who wants to win and handles the attention with poise and maturity.
Ultimately it's the character of guys like these that will make the 2014 Ducks a great team. Talent got them to the top, but commitment and focus will make them special.


text:
Browse other items in the Accents collection from Wayside Furniture in the Akron, Cleveland, Canton, Medina, Youngstown, Ohio area.
The Crete finished credenza features an exquisite, burnished finish with hand-painted detail. The detailed side-posts and antique brass finished hardware are complemented by the carved apron on the bottom of the center. The credenza has three drawers and three cabinets, each of which has an adjustable shelf. The versatility of this credenza makes it an ideal addition to your living room, dining room or any other space that needs extra storage and organization. Store dishes and utensils in dining room. Or you add to bedroom for clothing or keepsakes.Dimensions:Width (side to side): 66 inchesDepth (front to back): 16 inchesHeight (top to bottom): 40 inches
The Accents Crete Credenza by Pulaski Furniture from Wayside Furniture. We proudly serve the Akron, Cleveland, Canton, Medina, Youngstown, Ohio area. Product availability may vary. Contact us for the most current availability on this product.
Explore the beauty and elegance of this Home Accents collection. From accent chests, stools and tables, to pedestals and plant stands to bath vanities and bookcases, you will find the perfect accent to decorate your home. These accents provides just the right finishing touch for any room in your home. Discover the pieces that will so wonderfully reflect your unique sense of style. All of these items are made with high quality craftsmanship and delicate hand-painted detailing. The Home Accents collection translates elements from history into a lavish collection to to add beauty, enjoyment and value to your home.
The Accents collection is a great option if you are looking for furniture in the Akron, Cleveland, Canton, Medina, Youngstown, Ohio area.
This item has been tagged as: China Cabinet, Corner Cabinet, China Hutch, China Storage, Kitchen Storage, China Display, Dining Room Cabinet, Buffet, Hutch, Buffet and hutch, Buffet Server, Meal Serving Furniture, Kitchen Buffet, Dining Room Buffet, China Buffet, Buffet with Storage, Storage Furniture, Dining Room Furniture, Curio, Corner Curio, Curio Cabinet, Display Cabinet, Wall Curio, Console Curio, Lighted Curio Cabinet, Cabinet, Bakers Rack, Kitchen Storage with Shelves, Bakers Wine Rack, Dining Room WIne Rack, Kitchen Baker Rack, Sideboard, Sideboard with Hutch, Buffet and Hutch Set, Server, Serving Table, Server Table, Dining Room Server, China Closet, China Cupboard, China Compartment
Nothing on this page may be copied or reproduced without explicit permission.


text: There are two versions. The long version they show on TV (3+ hrs) and the short version you buy at stores (2hr 17min) Where can a get the long version on DVD. OR whats the best version to own, quality wise. I've been looking all over for the full version on DVD but have been unlucky in my search (This has been going on off and on for a while) I like them both but I don't wnat to by the cut version if the full length version is out there.


text:
Play free online games!
Hong Kong Phooey
Hong Kong Phooey
Play with your own profile by registering yourself for this fun game. You can also play as guest, but your scores and account will not be saved then.
User name / E-mail address...Password...
Forgot password?
Not all required fields were filled in
User unknown
User name...E-mail address...Password...Password (Once more)...
Username is too short or too long (between 3 and 12 characters)
Passwords too short (minimum of 5 characters) or do not reconcile
No avatar selected
No valid email address
Username or email address already in use
The username is invalid
Hong Kong Phooey
What do you think of this game?
Score: 3 (1 votes)
DescriptionTry to eliminate all Big Boss's helpers to prevend him from stealing the city's water.
|O = move left
P = move right
Spacebar = jump
Q = kick
A = chop


text:
Broken. The word "broken" can bring up powerful emotions or simple frustration. Context means everything. This morning Fr. Dave1 made repetitive use of "broken" during the Palm Sunday Liturgy of the Palms. Of course, the reference was to the body of Jesus, broken on the cross. Fr. Dave's sermon was powerful on this powerful day and I am drawn to think on current circumstances.
We too are broken. America, along with much of the world, has lost its moral compass. I'll say nothing more for fear of devolving into a political diatribe which is not the purpose today. But because of our brokenness, this Holy Week spurs me to repeat what I have done a few times during this time of year — to re-publish The Seven Trials of Christ. What better way to think about this brokenness but to study Jesus' sacrifice in a modern, judicial context. (Note that some poetic license is taken by some fictional accounts). As noted in footnote [1], this is a work that was begun by my father, Guilford L. Jones, Jr. — a fantastic lawyer from Big Spring who often delivered this as a speech, powerfully. I have done some modifications and additions, of which I hope "Big Guil"2 would approve. Continue reading "Broken – think upon the 7 Trials of Christ"


text:
I'm proud to announce I'll be one of the bloggers attending the Shot@Life Summit in Washington D.C from Feb. 10-13!!! I'm extremely excited to be a part of this project and help support an important cause. We will be talking about Childhood Vaccinations: A Global Perspective. We will be hearing about the Role of The United Nations Foundation, Vaccine Safety, Vaccine Resources and more! We will even have the unique opportunity to travel to capitol hill and meeting with members of Congress! This is one of the biggest accomplishments of my life to be a part of this program and I hope you will follow along with us via the #globalvax hashtag on twitter!
All About Vaccines
About Vaccines
Vaccines work. Immunization has saved the lives of more children than any other medical intervention in the last 50 years.1 Vaccines are safe, simple and one of the most cost-effective ways to save and improve the lives of children worldwide. However, many children in developing countries lack access to vaccines — often because they live in hard-to-reach communities and are among the most marginalized members of the community. Vaccines ensure that all children, no matter their circumstances, have a shot at a healthy life.
About Vaccine-Preventable Diseases
One in five children lack access to the life-saving immunizations that keep children healthy. In fact, approximately 1.5 million children in developing countries die each year of a preventable disease like pneumonia, diarrhea, measles and polio. Put another way, one child dies every 20 seconds from a disease that could have been prevented by a vaccine.
Coordinated worldwide vaccination efforts have made significant progress, particularly in reducing cases of measles and polio, but funding gaps could threaten these gains. Meanwhile, we now have vaccines that prevent the primary causes of pneumonia and diarrhea, the two leading causes of childhood mortality. Still, one in five children in developing countries does not receive the life-saving immunizations to protect them against measles, pneumonia, diarrhea, and polio.2
Measles is one of the most contagious and infectious diseases. It spreads through coughing and sneezing, and 90 percent of unimmunized people who come into contact with an infected person will catch measles. Though treatable in the U.S., the disease can be deadly in places without quality medical care, nutrition or sanitation.
- The Measles & Rubella Initiative has vaccinated more than 1 billion equivalent to half the children. The number of children dying every year from preventable diseases in developing countries is nearly children in 60 countries, reducing measles deaths globally by 74 percent.3
- Despite this progress, measles still kills an estimated 450 people each day—the majority of whom are young children.3
Polio attacks a child's nervous system and can cause muscle weakness, paralysis or even death.
- Thanks to polio vaccination, five million people who would otherwise be paralyzed are walking and polio cases are down 99 percent.4 Never before has the world been this close to eradicating polio.
- However, the disease has recently reemerged in areas that had been polio-free for years. Until permanently eradicated, polio anywhere remains a real threat to children everywhere.
- Polio remains endemic in three countries: Afghanistan, Nigeria and Pakistan. India was removed from this list in January 2012 thanks to the commitment of the Indian government, partners around the world,and over 2 million community health workers who vaccinated over 172,000,000 Indian children against polio.4
PneuMococcal disease is a bacterial disease that can cause meningitis and pneumonia.6 Preventing the disease through a vaccine is the only way to protect children from it.
- Pneumonia, the most common symptom, accounts for 18 percent of child deaths in developing countries, making it the number one vaccine-preventable cause of death worldwide.7
- In 2010 the GAVI Alliance, an international vaccine financing partnership, began a program to introduce pneumococcal vaccinations to more than 40 countries by 2015. Once at full capacity, the program would save 650,000 lives.
RotaviRus is the most common cause of severe diarrhea among infants and young children.
- Each year, more than half a million children under age five die as a result of rotavirus, and almost 2 million more become severely ill.8,9
- In July 2011, Sudan became the first GAVI-eligible African country to roll out the rotavirus vaccine. GAVI will support the introduction of rotavirus vaccine in more than 40 countries by 2015.
Make sure you are following the #globalvax hashtag Feb. 10-13 to follow along with all your @shotatlife Champions during the Summit!
— kasandria (@waystosave) January 26, 2013
About Shot@Life
Shot@Life educates, connects and empowers Americans to champion vaccines as one of the most cost-effective ways to save the lives of children in developing countries. A national call to action for this global cause, the campaign rallies the American public, members of Congress, and civil society partners around the fact that together, we can save a child's life every 20 seconds by expanding access to vaccines. By encouraging Americans to learn about, advocate for, and donate vaccines, the United Nations Foundation's Shot@Life campaign will decrease vaccine-preventable childhood deaths and give children a shot at a healthy life. To learn more, go to ShotatLife.org.
1 Public Health Agency of Canada (2009). Immunization.
2 UNICEF, http://www.unicef.org/immunization/index_bigpicture.html, October 2010.
3 Measles Initiative.
4 Global Polio Eradication Initiative. Infected Countries.
5 U.S. Department of Education, 2007
6 UN News Centre. New pneumonia vaccine targets leading cause of child deaths worldwide February 14, 2011.
7 Black R, Cousens S, Johnson H, Lawn J, Rudan I, Bassani D, et al (2010). Global, regional, and national causes of child mortality in 2008: a systematic analysis. The Lancet 375: 9730.
8 Simpson E, Wittet S, Bonilla J, Gamazina K, Cooley L, Winkler JL (2007). Use of formative research in developing a knowledge translation approach to rotavirus vaccine introduction in developing countries. BMC Public Health 7: 281.
9 Health Affairs, http://www.healthaffairs.org/press/2011_06_10.php, June 2011
***Disclosure: I'm attending The #globalvax . My flight, lodgings, and expenses were covered by Shot@life. All opinions are 100% mine. ***


text:
Image copyright:
Please sign in to comment. Don't have a profile? Join now! Joining is absolutely free and no personal information is required.
we lost one of our pygmy goats lately, she had liver fluke. apparently caused by eggs that live in water snails.. They had been wormed but not against that particular thing. Now we only have one and are trying to find another locally, of course prices have gone up sky high
A well deserved nap and proud mum! How cute!!! Thanks for posting, CallumEssex.


text:
The fact that Sam died should make us all keenly aware of the precious nature of our relationships while we're here and the frailty of human life. Sadly it appears this tragic and violent death turned into a worship of money.
U.S. District Judge Dale Kimball, in awarding Sam's estate the sum of $1.9 million, says the U.S. Forest Service was "required" to warn the family about a dangerous animal in the canyon. He said that the USFS owed them a duty "to warn them about the earlier incident, whether the warning was oral, by posting signs on the gate of Timpooneke Road 56, and/or by roping off the specific campsite."
The ruling seems foolish to those of us who spend time in the wilds. We know that "thar' be bears and dragons" there. We don't need the U.S. Forest Service to tell us. And, if they don't nanny our every move, we surely don't expect them to be financially responsible for us if we choose to spend time in the wilderness.
With such an obtuse ruling one can only speculate what the next level of government "protection" will be.
People drown in reservoirs on Forest Service managed lands. Will the USFS prohibit boating and fishing to raise their level of nanny protection to a standard that will not allow them to be sued again?
Snakes bite people wearing flip-flops on FS managed land. Will the USFS require everyone to do a snake-proof boot check before venturing where the snakes are?
Now they have the money, Sam's family claims they sued to prevent such tragedy from happening to others.
Their stated purpose for suing will be demonstrated when they donate their ill gotten gains to fund a "campers protection service" program ensuring that such a tragedy as happened in their family is never experienced by others. Until then, it's all about the money.
Nichols is dedicated to preserving the "American dream" for his grandchildren through conservative principles.