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To call Bruce Levine, PhD, an innovator in the cell and gene therapy space is a gross understatement. He is known for his groundbreaking work in the development and use of synthetic immune cells (or CAR T cells) to attack advanced cancer cells. Insight's Erin Righetti interviewed Levine to talk about his research and outlook on cell and gene therapies, and the importance of partnerships in progressing the field.
A sensational discovery
Twenty years ago, Levine, with Carl H. June, first began collaborations with a small biotech company, Cell Genesys, on a technique to genetically alter T cells to create synthetic immune cells, known as chimeric antigen receptor T (or CAR T) cells. With June, Levine had created a groundbreaking microbead technology to act as artificial substitute for the dendritic cells that give T cells the signal to attack cancer cells. This technology was the basis for the Cell Genesys collaboration and is now the primary method used by investigators to grow activated T cells.
"In the very early CAR T cell trials by several groups, there were some lab indicators that the cells persisted, that they were there, but clinical responses were minimal at best," said Levine. "We used microbead technology to more efficiently grow T cells and later, a disabled form of the HIV virus to deliver the CAR gene to T cells. Express of the CAR of the surface of T cells redirects and trains them to target the CD19 protein on malignant B cells and kills those cells."
At critical junctures in the Penn team's research, they ran out of funding. Research is expensive. Cell and gene clinical trial research even more so. "Over the last 25 years that we have been working in the field, adoptive immunotherapies have had a lot of peaks and valleys," said Levine. "In the 1990s and early 2000s, it was seen as something boutique of 'isn't that quaint,' and 'interesting, but it's never going to work.' This idea of redirecting T Cells or immune cells was groundbreaking. NIH grant reviewers saw it as a totally different paradigm than they were used to, and many comments were not kind.
"Then in 2004, we applied for a grant from the Alliance for Cancer Gene Therapy (ACGT). This foundation was started by Edward and Barbara Netter, who endowed my Chair at the University of Pennsylvania," said Levine. "Edward, who passed away six years ago from pancreatic cancer, was a graduate of Penn. They started the foundation in 2001 because their daughter-in-law, Kimberly Lawrence-Netter, was diagnosed with breast cancer and passed away from it. Edward was a polymath, interested in everything. After his daughter-in-law passed away, he heard about a seminar organized by Savio Woo, PhD, at Mount Sinai School of Medicine on gene therapy. It was then that Mr. Netter determined he would direct their Foundation's efforts to gene therapy."
In a 2010 trial in patients with advanced blood cancers who were infused with their own CAR T cells, pounds of leukemia then melted away over several weeks, according to Levine. "We were out of money, we had striking results and we were asking ourselves 'What do we do? If we publish we can get more grants.'" At that point in 2011, with no funding left to continue the research, June and Levine and their Penn team published their results, sparking a media sensation as to the potential of CAR T cell therapies.
Without the renewed interest of and resulting involvement by partners, progress on these groundbreaking discoveries may have never seen the light of day, so to speak. Partnerships have played an important role in progressing this research and have boosted the progress of Levine's recent work.
When they published in 2011, we had no idea of the press coverage it would generate, appearing in over 800 media outlets, resulting in 3,000-4,000 inquiries from people interested in the clinical trials. Penn had to build a website to take the inquiries that is still in use. The 2011 publications led to interest from industry in licensing the technology.
"Ten to 12 companies of various sizes, all the way up to Novartis, contacted us wanting to license and develop the technology," said Levine. "We then signed with Novartis in 2012. The partnership between the University of Pennsylvania and Novartis allowed the development of clinical trials of CART T cells in leukemia and other blood cancers in adults, and in children as well. The ripple effect of the Penn-Novartis alliance was a 'licensing and investment frenzy' across the US and now around the world among various biotech, research universities and hospitals."
Jump ahead to 2017 and two companies have submitted applications this year asking the FDA to approve CAR T cells for Breakthrough Therapy designation in the treatment of cancer. Novartis has already submitted for pediatric acute lymphoid leukemia (ALL) which has been accepted by the FDA. Later in the year, Novartis will submit for lymphoma. Kite Pharma has also initially submitted for treatment of relapsed or refractory aggressive non-Hodgkin Lymphoma (NHL).
Big pharma: Learning to speak the language
To put the Novartis collaboration in perspective, everyone in the field thought big pharma would never be interested in cell and gene therapies, it broke their business model from multi, continuous dosing to a one time or couple time infusion where immune cells are detected years after infusion. The collaboration spurred attention in the field as to what other groups were doing, followed by the work at Juno, Kite Pharma and other companies picking up steam. Said Levine, at last count there were three dozen companies in the field of engineering immune cells to redirect against cancer, including T cells and NK cells.
"We have had other industry partners in the time since the early collaboration with Cell Genesys in the 1990s," said Levine. "During my postdoctoral fellowship with Carl June, I had developed the magnetic bead technology to grow T cells, and Cell Genesys contacted us about research they were doing on chimeric antigen receptor T cells. That was the beginning of that relationship," said Levine. "Carl June and I were still at Naval Medical Research Institute at that time. When we moved to the University of Pennsylvania in 1999, inquiries followed from other companies about technology they wanted to get into clinical trials, including Sangamo BioSciences, to create HIV resistant cells using zinc finger nucleases in the first gene editing clinical trial in humans. We have worked with other companies including Virxsys, Adaptimmune, and Takara taking the technology they had developed into clinical trials, serving as R&D in clinical trial development and execution."
The role of partnerships in the development of cell and gene therapies and cures came up frequently for Levine.
"Over the past 20 years and even more recently, in the last five to ten years, there has been an evolution in how translational research and research in general works," said Levine. "Declining NIH funding, and signs of future cuts means academic investigators must rely more on philanthropy and industrial partnerships to conduct research. We have seen that at Penn, the balance between academic-initiated hypothesis research that is NIH grant funded and industrial targeted research; academia and industry need to learn to speak one another's language to collaborate."
Collaboration necessitates the need for creation of industry-wide standards for the commercialization of cell and gene therapies.
"Not only is it a new field but it's a new field in complex biology," said Levine. "Consider the traditional development of drugs and characterization of drugs, where small molecules are characterized at-will and made in big batches and delivered to patients. In cell therapy, you have a very complex entity. How do you characterize that in terms of potency and stability? That cell, especially autologous cells, varies greatly. How can you have a standard for that cell when they vary in so many parameters in different patients? Development of standards is important and difficult. We have had conversations on this with the Alliance for Regenerative Medicine (ARM), American Society of Gene & Cell Therapy (ASGCT), National Institute of Standards and Technology (NIST). One way to start is to look at instrumentation and determine reference standards, methods for counting, and methods for analysis. It's very complex.
"The cell I develop is not likely to be the same as the cell another investigator develops if any of the many elements of sourcing and manufacture are even slightly different," Levine said.
Making the case for early collaboration
For cell and gene researchers, there is substantial benefit in collaborating early, but how can they attract the attention and support of partners at an early, high-risk stage?
"That's a really good question," said Levine. "I wish we knew all the answers. It's simply a different audience. For an NIH review, there's a defined format and investigators are well versed in how to put their proposal together." Even so, many times researchers don't know who the panel reviewing is or how well their proposals will be received. There have been new developments in philanthropic research funding in the last 10 to 15 years, as well. "Philanthropies are now asking for return on their investment with regard to rights on their IP," said Levine. "This throws another wrinkle into the midst. If a company wants to license, they have to consider that throwback to the licensing stake."
So, how should cell and gene companies pitch? "You start with 'how is your research getting out there?' and is it being published?" said Levine. "You have to determine if the backbone behind the IP and knowhow is attractive to licensing, and then get assistance in packaging your pitch to outside companies."
Another critical but basic parameter is whether or not the research has been published. As evidenced from previous trends, there is a bandwagon effect when a concept or certain terminology gains popularity. Just look at the hype in recent years that culminated around stem cells, then nanotech, to name a couple. A partnership proposal can benefit from using popular or trending terminology, not in a sensational way, but in an intelligent way.
"The problem with a hot term is it can be hijacked. For example, so called stem cell clinics that skirt FDA oversight in pitching to patients and charging them for every indication under the sun where there commonly isn't a scientific rationale," said Levine. "You want to get attention for what you're doing but researchers and partners need to do due diligence on each other."
Back in 2010, Levine, June and the Penn team conducted initial trials of CAR T cells that targeted CD19 in three patients with advanced cases of chronic lymphocytic leukemia (CLL). Levine admitted that having partners at that very early stage would have benefited his work.
"We had some funding through the Alliance for Cancer Gene Therapy and the Leukemia and Lymphoma Society that took us to a certain point at a certain speed. We hoped, and it turned out to be case, that we had something extraordinarily promising," said Levine. "Had we had more funding earlier it would have developed more rapidly. We are excited and grateful for our alliance with Novartis for the opportunity to develop that.
The impact of patient advocacy
Cell and gene researchers are increasingly working with patients and patient advocacy organizations to reach a global community to advance their research and open doors at the drug policy level.
"The involvement of patient families and related groups is extraordinary," said Levine.
Levine related a story of the first child treated with CAR T, Emily Whitehead, which was reported in the New York Times and other popular news, as well as being the subject of a 2012 documentary, "Fire With Fire" filmed by Ross Kauffman, an Oscar-winning director. Whitehead became a celebrity patient, appearing on Stand Up 2 Cancer and featured at the April 2016 opening of Napster and Facebook billionaire Sean Parker's Parker Institute for Cancer Immunotherapy, as well as meeting President Obama and Vice President Biden, among others.
"When the New York Times (NYT) story first appeared in 2012, the staff at NYT said to the Whitehead family 'Beware of the tsunami.' The Whiteheads were very quickly contacted by media outlets and other patients around the world," said Levine. Shortly thereafter, they founded a philanthropic foundation, the Emily Whitehead Foundation - Activate the Cure, which has funded the work of June and Levine and collaborators at the Children's Hospital of Philadelphia in CAR T cells.
"This is an example of a girl who had failed all available therapies, who did not have long to live, whose parents enrolled her in a trial, she became a complete responder, and they are all now paying it forward in so many tangible ways in support of other patients. They are heroes," said Levine.
Many patients desire to meet scientists who develop their cells and conversely, the scientists get to know their patients. Levine and his group frequently work with patient groups, foundations and advocacy organizations such as ARM. One of Levine's former patients is on the Lymphoma & Leukemia Society board advocating for future therapies. Advocacy has a strong impact on top level decision makers, such as the NIH-backed Cancer Moonshot program which involves external experts from industry and advocacy. "When President Obama announced Cancer Moonshot, our labs were the first stop Vice President Biden made after the announcement," said Levine. "He was here over two hours, and returned again just six weeks ago."
Levine will be participating in Cell & Gene Exchange, a partnering forum focused on the regulatory, business, and patient advocate communities in cell and gene therapy sectors taking place May 22–23 in Washington, DC.
Partnering is the essential link to progress
"This is the first event of this kind ," said Levine. "The idea is that this is no longer a small percolating field; it's now evolved to the point where we have new considerations for therapies that are going to approved and commercialized. It is real.
"There has been a cascade effect and the number of companies that have started in the field has increased exponentially these last few years," said Levine. "It is important to have a forum where experts in the field can hear from new companies. Producing CAR T cells require a complex and multi-step process, and all along the way you have ancillary reagents, technology, logistics, and so many pieces that go into it. The ability to partner is important to advance the field and promote understanding that this is a unique technology. Partnering is essential and required, it's not optional."
"I've been involved with ARM for a number of years, as we work toward scale out of CAR T cell manufacturing," said Levine. "I am making an effort to free up more of my time to be locally, nationally and globally engaged in advancement of cell and gene therapies. For me, personally, the timing is right, and with the recent filings for Novartis and Kite, there will be even more awareness of this field, and we are looking to ARM to raise awareness in Washington for these new therapies with regard to policies and regulation."
At the end of the day, Levine attributes his inspiration to the people who will benefit from future therapies and cures. "It's the patients. No question about it," said Levine. "As a PhD, the ability to do work that is not only interesting but has application to new therapies, that is the ultimate reward; to be able to meet patients who have been impacted by this work. Just to have the opportunity to have been mentored by Carl June and now to be part of a large team starting in research all the way to translation to clinical labs, to see that large team of dozens of experts coming together to get therapies to the clinic and to see the patients has been very rewarding. I think we all feel very fortunate to be in this space at this time, and we owe a great debt of gratitude to the patients whose families enroll in these trials without whom we would not be able to develop new future therapies."
Meet Bruce Levine at Cell & Gene Exchange to hear more about exciting developments in the cell and gene sector, and meet with leaders from patient advocacy groups, industry, academia and government to explore partnership opportunities, exchange ideas, and network with the goal of advancing the development of potentially curative therapies for life-threatening diseases.


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|Property type
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See www.houseinfrance.net au for a detailed description of both our houses in Vinsobres.
Chez Hubbert is on 3 floors. The ground floor has the kitchen lounge and terrace; the top has 2 bedrooms, and a bathroom, and the lower floor has 2 more bedrooms and another bathroom, as well as beautiful garden with a fantastic view out over the vines.
The middle floor is on street level but at the back of the house it opens out onto a lovely terrace with magnificent views. From the front door entrance you come into the foyer then through to the gourmet kitchen. A door off the kitchen leads through into the loungeroom. Both the kitchen and lounge have doors which open out onto the terrace. There is a large outdoor table and chairs on the terrace for enjoying outside meals under the shade of the pergola. There is also a BBQ at the end of the terrace.
The upper floor is accessed by a stone staircase from just inside the front door. Halfway up on the left is the main bathroom with toilet. Then there is the second bedroom with twin beds which can be joined together to make another kingsize bed. Further on down the hall, there is the main bedroom with kingsize bed and french antique furniture. The views from this room and the hall window are spectacular, looking out over the vineyards.
The lower floor is accessed by an ancient stone staircase leading down into the peaceful garden. From there you enter the two downstairs bedrooms, bathroom, shower and separate toilet. The view from the garden is quite spectacular, looking out over the vineyards and olives. There is another table with seating for four, as well as two lounge chairs to relax in.
We have recently installed a hot tub in the back yard for relaxing after a long day exploring or cycling!
We initially purchased the 4 bedroom house in Vinsobres because we wanted to leave in France to enable our son to attend school for 18 months. We had always dreamed of living in a stone house in a village on a hill, surrounded by vineyards, and the dream came true!
We are now based back in Australia but intend to maintain our connection with the South of France.
Graeme Hubbert purchased this villa in 2007
We purchased this particular property after looking at 37 properties in the Rhone Valley in a period of 2 weeks around Easter 2007. We settled on the region around Nyons and Vaison la Romaine because of the unique appeal of the area. This narrowed the search to a largish stone house in a perched village in that region. Luckily we found 14 Rue Reynarde and named it 'Chez Hubbert'.
The region is a fantastic mix of historic stone villages, cycling (Mont Ventoux is 29kms from the house), wineries, olives, lavender, breathtaking scenery (although in the Rhone Valley the Alps are not far away), skiing in winter.
Vinsobres is a small perched village, located on the border of Drome and Vaucluse, in Provence, with the mountains on the doorstep.
We love the village and the region so much that we have recently purchased another house in Vinsobres - Le Trillon - an 800 year old rampart tower - which has been renovated in style with its history and now rents as a beautiful 2 bedroom village house
Vinsobres is in a beautiful part of Southern France, with a wide variety of things to do and see. Views take in rich lavender fields, grapevines, and the soft grey of the olive groves.
Nyons is only 7 kms away at the foot of the Alps, and has a very lively market held every Thursday throughout the year, as well as many cafes and restaurants. The historic town of Vaison la Romaine is 15 kms in the other direction with the historic town separated from the not-so-old town by the river. Vaison has a very large market on Tuesdays.
Mont Ventoux, of Tour de France fame, is only 30 kms from Vinsobres and represents the ultimate challenge to keen cyclists. There are countless picturesque cycling routes to practice on before attempting the ascent of Ventoux!
It's about an hour north-east of Avignon (with a TGV station), and less than 2 hours to Marseilles. 40 minutes from the nearest TGV station at Montelimar. Paris is only 2 hours 40 minutes by TGV to Avignon, and 2 hours 20 minutes to Montelimar.
This area of Provence is truly a place for all seasons. In March the spring flowers push through; April sees the fruit blossom; May the vines bursting into leaf, greening everywhere, and the first strawberries and cherries turn up in the markets. More fruit and salads in June - and the hillsides are cloaked in lavender. July and August are high season - with village's fetes, music festivals, and more. And there's always a breeze to cool things off. There's a gigantic outdoor Municipal Swim Center with cafe - a great place for cool family fun in Nyons, and another memorable public pool is found beneath the Marquise-de-Sevigny's huge Renaissance castle at Grignan. While you're there, Chateau Grignon is well worth a visit, as well as touring the local shops. Closer still is Franceloc, with its huge water amusement park, just a kilometre down the road on the way to Nyons.
There are too many wineries to count in the area, as well as other places to sample the delicacies such as the famous Nyons' olives and oils, lavender, apricots, honey and nougat. You won't run out of places to visit or things to see and do. Vaison la Romaine has recently discovered Roman ruins and Grignon with it's superb castle is only 20 minutes away in the opposite direction. The Count de Grignon ruled the south of France prior to the French Revolution and the castle has been faithfully restored by the French Government.
North from Nyons are the scenic gorges and then the beginning of the stunning French alps with great skiing in winter, hiking in summer and breathtaking scenery. Marseilles and the Cote d' Azur is about and hour and a half drive south and Avignon is also only 45 minutes south.
Chez Hubbert is on 3 floors. The ground floor has the kitchen lounge and terrace; the top has 2 bedrooms, and a bathroom, and the lower floor has 2 more bedrooms and another bathroom, as well as beautiful garden with a fantastic view out over the vines.

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FINER method
1) feasible
2) interesting
3) novel
4) ethical
5) relevant
positive controls
those that ensure a change in the dependent variable when it is expected
Negative controls
ensure no change in the dependent variable when no change is expected
confounding variables
error that results when a causal variable is associated with two other variables but is not accounted for; may falsely say two variables are associated
observational studies
can be cohort: those in which subjects are sorted into two groups based on differences in risk factors and then assessed at various intervals
cross-sectional studies: attempt to categorize patients into different groups at a single point in time
case-control studies: start by identifying the number of subjects with or without a prticular outcome
Hill's criteria
describe the components of an observed relationship that increase the likelihood of causality in the relationship
1) temporality: exposure must occur before the outcome (independent before dependent)
2) strength: as more variability in outcome is explained by variability in study variable, the realtionship is more likely to be causal
3) dose-response relationship:as the study or independent variable increases, there is a proportional increase in the response; the more consistent it is, the more likely it is to be causal
4) consistency: the relationship is found ot be similar in mutiple settings
5) plausibility: reasonable mechanism for the independent variable to impact the dependent variable supported by literature
6) consideration of alternate explanations: remaining explanation is more likely
7) experiment; if experiment can be performed, a causal relationship can be determined
8) specificity: change in outcome varibale is only produced by an associated change in independent variable
9) coherence: new data and hypothesis are consistent with the current state of scientific knowledge
detection bias
results from educated professionals usign their knowledge in an inconsistent way
selection bias
subjects are not representative of the target population
observation bias
hawthorne effect: people chang ebehavior because they are being studied
internal validity
suppor for causality
external validity
generalizability: ability to apply findings to another population
low generalizability: sample not reflect target populaton
high: samples represent target population
statisticalyl significant
not result of random chace
clinical significance
practical importance of a treatment effect - whether it has a real genuine, palpable, noticeable effect on daily life.
internal validity
ability to infer causality from a study or replicate its results under the same conditions
skewed distribution
one that has a tail on one side of the data site
negatively skewed distribution
mean is lower than median and tail is to the left
positively skewed distribution
mean is higher than median adn tail is to the right
interquartile range
first quartile
: multiply n by 1/4
--> if a whole number
: the quartile is the mean of the value at this position and the next highest position; if it is a decimal, round up to the next whole number and take that as the quartile position
third quartile
: multply n by 3/4
--> follow same instructions
any values that fall more than 1.5 IQRs below first or above third quartile
Standard deviation
1) first, determine value of mean
2) find diffrerence between each data point and mean and then square the value
3) add the squared values and divide by n-1
4) take square root of that
null hypothesis
always a hypothesis of equilance
alternative hypothesis
nondirectional or directional
rely on the standard distribution or the closely related t-distribution
1) a test statistic is calculated and compared to a table to determine the likelihood that that statistic was obtained by random chance: called our p-value
What do we do with our p-value
compare it to a significance level (alpha)
p > α
: we fail to reject null hypothesis, meaning there is not a significant differenc ebetween the two populations
p < α
: we reject the null hypothesis and state that there is a statistically significant difference between the two groups
if the alternative hypothesis is not directional, compare our p-value to α/2
type I error
value of α is the level of risk that we are willing to accept for incorrectly rejecting the null hypothesis
likelihood that we report a difference between two populations when one does not exist
type II error
occurs when we incorrectly fail to reject the null hypothesis
likelihood that we report no difference between two populations when one actually exists
sympbolized by Beta
confidence intervals
determine range of values from the sample mean and standard deviation
we begin with a desired confidence level (ex: 95%) and use a table to find corresponding z and t score; when we multiply from teh mean, we create a range of values and can then say we are 95% confident that the sample falls between those two values
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Sometimes you find a new path in life that never expected to take. It can really freak you out sometimes. You don't ask for it, you don't even want it. You want something else, and you chase it. It runs from you. You are heartbroken. You give up and ask for guidance. And then…something beautiful happens.
Ever since I was a young child, I knew I was strange. Kids made fun of me, my teachers said I talked too much in school, and I was overly emotional about things. Particularly animals. Especially if they were orphaned, homeless, or sick. I would bring them home, full of mange, or fleas and beg my Mother to let me keep them. I would cry for hours when she would say no. This led me to have many short term, and a couple of great long term pets. I was like this with friends too. Humans are different. A lot of times I ended up hurt and friendless. It was confusing and very hard at times. It still can be.
I have always been sensitive to people and places. I can still walk in a room and feel spirits, vibrations, tension, or love. For the longest time, I also saw spirits, heard them speak to me, and repeated their chatter for some time as a paid psychic medium. One day back in 1998, I heard from a spirit who had been murdered. I knew of this person, but did not know her, or know anyone who knew her. She had disappeared years before. Her body was never found. The chain of events leading me to this were very frightening for me. She wanted me to contact her Mother, and tell her everything that her murderer had done. It was much too gruesome for me to deal with. I decided it was best to turn off my abilities. So…I did. My husband didn't believe in this strangeness at first. He came to believe that I wasn't crazy. He supported my strange experiences because he witnessed some of them being confirmed by others. Thank goodness I didn't lose him in the process of all that.
For some time I went without allowing any of the spirit entities to speak to me. I still have a problem with ever doing any of this work again. The dead are better left to keep silent. It dredges up things that I myself feel should be left alone. And, there could be spirits that trick us and I truly believe this is just not kosher. For myself, or anyone else. Laugh if you will, but things can get dark. I am not alone in these experiences. There are many who have had them. We just keep our mouths shut because of the reactions we get.
Now, there are some things I chose not to turn off. I just didn't know what they were. I recently found out names for these gifts. I am a total empath, and an intuitive. We are all this way, but most people choose to ignore it, or don't have their third eye open, so they don't know. I've accepted this, and have been delving into how to live with it.
What is an empath? This will explain it much better than I can.
I recently connected with a very dear friend whom I had lost touch with. He is also an empath, intuitive and psychic. We have had a great time reconnecting, sharing, and encouraging one another to discover where we belong in this world. Why we have these gifts, and what we are to do with them. We are very misunderstood in this world. It makes life hard sometimes. People make fun of you. They think being psychic means you are like those fake people on television, and that we should know the answer to everything. That's not how this works. We take what we are given and listen. We take action and move forward with what we have, to help others and ourselves spiritually grow. Now I am not talking about a religion. There is a huge difference in religion and spirituality. I don't subscribe to one religion. I do believe we are governed by the universe, and many things around us. But that is another conversation. I just wanted to make that clear.
This all leads me to my latest experience. I woke up Thursday morning (Oct. 24, 2013) feeling horrible. I felt alone, sad, frustrated, and confused. Mercury Retrograde began Monday, so I was already aware that this was going to happen, but it was specifically about my abilities. I was having a hard time tuning the negativity out, and I ended up meditating longer and doing some Yoga. I spoke to my online friends about what I was feeling. I got many loving responses from other empaths and intuitives. I was having trouble getting my messages from the spirits. I wanted to let the positive ones back in (spirit guides etc.) and learn how to listen. It wasn't coming. I had been struggling for weeks now. I had only a couple of messages from my main spirit guide – Falcon. That's a whole story in itself as well. Another entry.
I was talking to my friend on facebook, and he said something about being a cat sometimes. I said – "I'm always a bird." When I said that, spirit allowed me to hear Nelly Furtado's song 'I'm like a bird' pop into my head immediately. I looked up the lyrics and began to cry. This was the first sign. Finally, I was getting somewhere.
After that first sign, my dear psychic friend called me. His timing is always impeccable. We were talking and I picked up the mail from outside. I saw a magazine from a Fraternity. WTF? Why did I get this? It's from Carmel Indiana? I have NO clue why I would even have gotten this. Alpha Sigma Phi? Strange. I threw it down and forgot about it. I went through my day waiting for signs about how I would be getting information. Nothing more.
I then went to an empath community forum I had recently joined. I was doing some reading to prepare myself for how to deal with my new found abilities. I came upon 'The Book of Storms'. This is a lesson on how to develop my abilities further, and I began to read the chapter on "dreamtongue". Here it comes! It's based on the Greek alphabet. How often does that come up? Thank you! The fraternity magazine! Whoa! Another sign. I'll take that. I have to. There is no other explanation.
My hubby came home and immediately announced he wanted to watch a movie. I said nothing to him about my strange day, or any of these signs. I didn't want to talk about it. I just wanted to relax. I agreed we should watch a movie later. We ate dinner and settled in to do just that. My hubby has a propensity for dark humor and movies. He wanted to watch a movie about the Holocaust. I immediately grabbed the remote.
Me – "That's just not gonna cut it tonight. I have had a very strange day, and I can't do Hitler tonight."
Him -"You pick something then. I'm cool with that. I just don't really want to watch a documentary."
I scanned through Netflix looking for a comedy, or something light and positive that wasn't a documentary. I landed on a movie called 'Jeff, Who Lives at Home'. "This looks good." I said. I had never heard of this movie, nor did it give any kind of description leading to what it was really all about. So we began to watch. As we watched, I began to tear up. The movie was all about allowing the signs around you to speak to you, and lead you where you are supposed to go. The whole time, the main character in the movie was suffering confusion about life. His family and all the people around him were making fun of him. He continued on, not letting it phase him. By the end of the movie, the message couldn't have been clearer. I refuse to reveal spoilers here. You just have to watch it. This one thing, at my husbands suggestion, had opened my eyes. The signs are everywhere. You just have to go with your gut. Don't be afraid to listen or see. How could it be? It just is. I shared it with him. Of course he was silent at first, and then encouraged me to review everything and make sure I wasn't going by coincidence. I explained. He agreed it was strange. The video – Cool! The magazine – No explanation whatsoever; but the movie, yeah, the movie was dead on yelling at me. See the signs! Pay attention to what is going on around you. We are all here to guide you.
Now I know. Now I see. I even got other messages that evening. And they keep coming. Subtle messages sometimes, and sometimes strong ones, but I'll take them. I'll go with them. I'm not crazy! I am an intuitive, psychic. An empath. A Blissworker. I know why I am here now, and what my path is. This is why I have to leave places sometimes. This is why I feel dark vibrations and good vibrations, Love, hate, all of them affect me in a strong sense. The only way I can explain this, is to say that sorting them out, is like hearing a multitude of radio stations at once. I have to find the ones I like and tune out the others. It's not so easy to do. If you have these gifts, you know exactly what I mean. Meditation is a constant need. Peace and silence are what we seek. It's all coming together now., and I want to use it to help others. I just have to continue to sort it all out and learn how. It's coming. I'll let it flow. Just be patient with me. I hope you understand. I hope you will still want to talk to me, and be my friend.
I love you all, and yes… I finally love myself. This is just the beginning of my new path. We are all on our own. I hope you look for yours, and you listen to the signs, and find your path. It's out there, and it's beautiful once you find it. Don't be afraid. All the right people will accept you. All the wrong ones will leave your life. It's okay. You are on your own path.


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About Us
About Press Media Release
PRESS MEDIA is a free directory that provides online Press release service with online content SEO services. Your press release will be published on PRESS MEDIA Networks, listed in popular distribution directories and PR partners sites, social networks like Facebook, Twitter, Google+, etc plus major search engines and news sites like Google, Google News, Bing, Ask, Yahoo!, Topix etc.) Your Press Release will also be available through our RSS Feeds and sent directly to journalists, other media professionals and to hundreds of newsletter recipients.
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- Attach a relevant photo/image of at least 800 pixel width
- Do not use CAPITALS except in the press release main title


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Sticky Tape Roll Supporting Hooks- Sticky Tape Rolls used for Monitoring and Scouting of insect pests
Product Options
Product Details
Support hooks are used for supporting sticky Tape rolls for monitoring and scouting of insect pests like fungus gnats
Questions or Comments?
Ask your question in the Questions and Comments area below.
Or send us a note using our contact form!


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Kindle Oasis $199 from Amazon Warehouse Deals (Used)
If the high price of Amazon's Kindle Oasis is putting you off from getting it, there's a way to get one for a lot less through Amazon Warehouse Deals. Currently they have two versions of the Kindle Oasis available used in "good" condition. They are most likely customer returns since the device has only been […]Read more


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Join the Rams! The 2017 season is underway but we're always recruiting!.
Register your interest here »
Welcome to the new home of your Yorkshire Rams
Based in Middleton, south Leeds, the Rams have been proudly representing Yorkshire in kitted American Football for over 25 years.
Rams Store
The official Yorkshire Rams online merchandise store is open for business!


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I decided to update my calendar since I got my work schedule today - I am in fact not going to be working the same hours as last quarter. Seems that my computer talents are in high demand (HAH), so I'm doing 9am-1pm computer floor support every day.
I don't really mind the schedule change. Meridan is going to switch his schedule to match mine, so he can take me to work, and even though I get done several hours before him, I can either stick around and do homework or take the bus home. The nice part is that if I do bus home, it'll be light out. Yay!
God, I'm so glad it's Wednesday. I have so much to do this week, and I really need Meridan's help. Gotta finish Christmas shopping, buy groceries, hunt down the rest of my schoolbooks, and do a crapload of other things. Sigh.


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Welcome to the National Association for the Self-Employed supplemental health insurance program offered through Rezilient Direct.
We are honored to have the opportunity to serve the Self-Employed who are the backbone of our economy.
Supplemental Insurance should be an essential part of everyone's healthcare planning. Our policies cover expenses that major medical insurance does not pay or provides coverage for those who are uninsured.
It's extremely affordable, easy to enroll with three simple steps and takes less than five minutes to complete. There are no medical tests required, coverage in as little as 24 hours, premiums are fixed and you can manage your policy through our website. Best of all it pays cash directly to you.
Go ahead and get a quick quote now and see how this coverage can benefit you, your family and your employees.


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Learning together what is good and right. JOB 34: 4
Easter performance song words are now available on the webpage for the children to learn the words
Welcome to Year 4!
Year 4 is led by Miss Sarah Campion
We also have a School Direct Trainee Teacher with us this year, Mr John Hicks
TA support - Mrs Gill Rieuwerts (Thursday and Friday)
If you have anything you would like to discuss with Miss Campion then please pop in after school or early in the morning. If more than a few minutes is required then please make an appointment - mornings in particular are very busy times so if more than a few minutes is required then please make an appointment.


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Lot of people use Income tax India website for different purpose. Main reason is to file the returns. I agree that desktop or laptops are the most proper devices to file your returns.
But, there are many other services for which people are using website. For example, checking Juridiction details or checking 26AS balance.
Does Income Tax India has any mobile app? Incometaxindiaefiling website is not even mobile friendly.
Posted 2 years, 5 months ago by Rahul Rai
As per my knowledge there is no app developed by income tax department. However when you go to play store you can find 1 or 2 apps.
Posted 2 years, 5 months ago by Mukesh Jain CA
Your Reply:
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Silvye Alves is a Brazilian Television presenter.[4] She is the host of Cidade Alerta.[1]
Early Life and Education
Alves was born in Goiânia and raised in Palmas, Tocantins. When she was 13, she worked as a sales clerk. Alves knew she wanted to be in television at a young age and started to become involved in the industry when she was 17.[8]
Alves has lived in four countries and speaks four languages. She started out as an intern for the Italian state-run media RAI and was promoted to a full-time reporter. Eventually, Alves moved back to Goiânia to be closer with her family and was hired by a local network, Record. Alves is the host of Cidade Alerta.[7]
Alves has a growing following on Social media with over 12,000 likes on Facebook and nearly 10,000 followers on Instagram.[4] [2]
Personal Life
In 2016, Silvye's boyfriend, investment advisor Thiago Friaz, proposed to her while the were on vacation in Europe.[8]


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Product Information
Protect your home, business or loved ones with this state of the art CCTV kit. Consisting of two super high resolution 540TVL outdoor cameras and two high resolution 540TVL dome cameras this system really does cover all aspects of personal security, with more connectivity with PTZ cameras, POS, ATM, Alarm and Audio devices. With the push notification it supports, SECURIX users can have real-time alerts for motions occurs in their premises via their iPhone, iPad and iTouch (using the SECURIX iPhone App. available for download from the app store). A simple user interface and wizard based set up ensures that even the novice user gets the most out of their home security setup with the minimum of fuss. The bullet cameras are even resistant to tampering with their anti-cut cable system. This SECURIX CCTV system is the home security system that homes and business have been waiting for.
- Professional H.264 Network DVR with real-time display(200ips), recording(200ips) and playback(200ips)
- 1TB SATA Hard disk storage built-in
- Free iPhone Application(SECURIX Mobile I) downloadable from Apple AppStore and Windows Mobile provided for monitoring
- Push notification for your iPhone to alert you activity on your cameras as it happens
- 2x Super-high resolution 1/3 CCD 540TVL Dome Cameras with IR LED
- 2x Super-high resolution 1/3 CCD 540TVL Weatherproof Bullet Cameras with IR LED and IR68 rating
- Bullet cameras include anti-cut cable brackets
- All Cameras with 20 meters night vision and Auto white balance
- POS and ATM interface via built-in RS232 port for recording and playback together with Text-in data
- PTZ(Pan Tilt Zoom) camera interface via RS485 port and support more than 60 different PTZ protocols
- 4x Audio input & 1x Audio output
- 8x Alarm input & 1x Alarm relay output
- 4 x 60ft long BNC and Power extension cable included
- D1 resolution support for clear recording and playback images
- Recording setup programmable for each cameras independently
- User-friendly Graphical User Interface (GUI) Menu System
- Day/Night: Yes
- Effective Pixel Resolution: NTSC: 720 x 480 • PAL: 720 x 576 Pixels
- Resolution: 540 TV Lines
- Image Compression: H.264
- IR Illuminatiuon: Yes
- Brightness Control: Automatic
- Video Resolution: 720x480 (N), 720x576 (P)
- Frame Rates: 30/25 Per Second
- Storage: 1000 GB
- Network Interface: 1 x RJ-45
- Video Out: 1 x RCA • 1 x VGA
- USB Ports: 2 x USB 2.0
- Input Ports: 8 x BNC
- Network Protocol: Manual, ADSL, DHCP, DVRNS
- Network Speeds Supported: 10/100 MBps
- Operating System: Linux (Embedded)
- Environmental: Operating Temperature 5 to 40 °C - Humidity 0 to 90 %
- Form Factor: Camera Kit
- Internal/External Use: Internal and External
- Weatherproof: Yes
- In The Box: 1 x 4 Channel Professional DVR System • 2 x Indoor Dome Camera • 2 x Indoor/Outdoor Bullet Camera • 1 x IR Remote Control • 1 x USB Mouse • 4 x 60ft BNC Cable • 2 x Power Adaptor • 2 x Power Cord • 1 x Power splitter cable
- Dimensions: 26.5 cm (W) x 5.2 cm (D) x 18.8 cm (H) - Weight


text:
24/7 Emergency Services
Serving Chicagoland, Oswego, Bristol, Yorkville
Installed new CertainTeed Landmark shingles in Shakewood color. It was a pleasure working with these homeowners!
View All Before and After Photos
our service area
More Cities
Or call us at
1-844-295-0315 1-630-524-2621
© 2017 Advanced Roofing Inc.311 E Van Emmon StYorkville, IL 60560
Contractor ID: IL License 104-011690


text:
Skill Points part 2
Edit Page Last Edit:
EditSkill Points
|Battle- dome
|Catacrom Four
|Valix Belt
|Planet Torval
|Ghost Station
|Piece Meal
|Use the B6 Obliterator to kill 20 enemies in a row.
|Nap Time
|Your Combat Bots must gain 15 kills in any challenge.
|Crank It Up
|In the challenge "On the Prowl," manually turn at least two bolt cranks.
|The Perfect Mod
|Kill five enemies using two different mods in 30 seconds.
|All Scattered
|Complete any challenge using only the Magma Cannon.
|Lights Out
|Deploy the EMP on three turrets in any challenge.
|Tough as Nails
|Complete a Catacrom Graveyard mission on Exterminator Difficulty.
|I Dare Ya!
|Complete any challenge without healing.
|Cha Ching
|Find and break five Jackpot Crates.
|Break 10 breakable objects.
|Camera Shy
|Break five hovering cameras.
|Chase the Goose
|In the challenge "Hoverbike Madness," finish with more than five seconds left.
|Derby Death
|In the challenge "Destruction Derby," kill five enemies at once with mortars.
|Kill 25 enemies without taking any damage.
|Holey Warriors
|Use the Dual Vipers to kill 10 Zombies.
| Deadlocked Guide feedback Give us feedback!
|Continue Skill Points...
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text:
Tax attorney costa rica
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no subjectDate: 2012-01-01 02:29 pm (UTC)
From: nasty-show.livejournal.com
Happy New Year, I hope 2012 is a better one for you *cuddles*
no subjectDate: 2012-01-04 08:30 am (UTC)
From: metatronis.livejournal.com
Thank you! I hope it's a good year for all of us.
no subjectDate: 2012-01-03 07:22 pm (UTC)
From: grrgoyl.livejournal.com
Boy, it looks like EVERYONE I know hated this year! I feel a little guilty that mine wasn't that bad (got to see Rickman, saw my little niece, etc.) I hope you have a better 2012 :)
no subjectDate: 2012-01-05 08:45 am (UTC)
From: metatronis.livejournal.com
Yeah, most of the people I talked to had a pretty crappy year.
I hope it's good too!
I hope it's good too!


text:
Plymouth Centre
Beauty Training Courses in Plymouth
If you would like to join the ranks of beauty therapists right across the United Kingdom, you're definitely in the right place. We are Chic Beauty Academy and are one of the nation's foremost beauty academies charged with the task of training the country's potential future beauty therapists.
Chic Beauty Academy has been helping the beauty therapists of tomorrow gain all the experience they need to thrive in the industry and we are proud of the superlative service we have provided since (year). For accredited beauty courses that are so enjoyable you won't want to leave-we're the academy for you.
So don't delay. Take that first step towards achieving the career you've always dreamt of in the beauty industry. If you would like to get in contact with us regarding beauty courses in Plymouth, click here to be taken to our contact page where you'll find all our contact details.


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*The board below is clickable, simply click on the item to be taken to the website to purchase* It's finally here people! The early access to the Nordstrom Anniversary sale has officially started today and I am sharing 20 of my favorite items from the sale! This is the BEST sale of the year and the perfect time to stock up on all your fall ... READ MORE
My Favorite Items from the #NSALE
The items on the collage are shoppable, click on any item to be take to it! The Nordstrom sale is here in full force! It's basically like Christmas for all blogger babes and fashionistas and we couldn't be more excited about it! If you have a Nordstrom debit or credit card you can shop the early sale now, but if you aren't, don't worry ... READ MORE
Shop my favorites below by clicking on the images. Hey friends and happy hump day! Neon colors are my favorite to wear in the Spring and Summer, so today I am sharing some items that I am currently loving. So far I have seen so many fun neon colors online and in store! From clutches, to heels, to even earrings, they have it all! Some items ... READ MORE
Bright Colored Embroidery Dress
Mint Julep Boutique dress c/o | Nordstrom sandals | Marley Lilly clutch c/o | Loren Hope cuff bracelet | Marley Lilly earrings c/o | NYX lip gloss Don't you just love it when an outfit goes to perfectly together without even putting any effort into it? Well this look was one of them. I picked out these earrings and this clutch from Marley Lilly ... READ MORE
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Ratings based on 104 Verified Reviews
3.0 Room cleanliness
3.1 Service & staff
2.8 Room comfort
2.6 Hotel condition
Expedia Verified Reviews
by A verified traveler
They need help.Posted Sep 17, 2017
Reservations were lost. Front desk clerk had to have a security guard check to see if someone was in my room already because he wasn't sure. First room they tried to have me stay in the carpet was soaked and they had industrial fans trying to dry it out, smelled horrible. Got a different room. Smelled like a bar, cigarette ashes on the carpet and counters - paid for non-smoking room so not happy there. No one available at the counter to check out in the morning. Pillows were awkwardly small and uncomfortable. Had to park extremely far from room in an area that was sketchy fo begin with. Had I not already pre-booked days prior and wasnt about to pass out I would've stayed elsewhere. Literally a hotel that I feel like had seen it's fair share of murders and prostitutes 100% would not recommend
Comment from Hotel Management
Sep 21, 2017 by Manager, Hotel Management
I am terribly sorry to hear of your disappointment with our hotel. We are truly sorry that you were displeased with your recent experience here in our hotel finding our staff rude. We understand how frustrating and upsetting this must have been for you and this is definitely not the usual standard of service we are held to provide our guests. Your feedback is reported to our management, I assure you that this is addressed accordingly. Kind regards.
by A verified traveler
Horrible surroundings and room.Posted Jul 15, 2017
I will never choose another econo lodge again. Bad neighborhood and dishonest workers.
Comment from Hotel Management
Jul 28, 2017 by Manager, Hotel Management
We also appreciate your comments regarding the ways that we can improve upon the guest experience in our hotel.We are working on the issues that you addressed and we thank you for taking the time to share your experience.
by A verified traveler
Posted May 30, 2017 on Hotels
by Kenneth
UncleanPosted May 30, 2017 on Hotels
They have bed bugs there! I got up the next day with red spots all over my body! I wouldn't recommend anyone stay here!
by A verified traveler
Posted May 20, 2017 on Hotels
by A verified traveler
Horrible customer servicePosted May 2, 2017 on Hotels
Rude Rude and Rude customer service the night manager is nasty and doesn't respect Hotel.com reservations. I LEFT and went to stay across the way at Days Inn
Comment from Hotel Management
May 10, 2017 by Reena Shah, Hotel Management
We respect all the reservations we get and also all the clients we get. I am sorry you felt this way and we will definitely try to improve as we do care for our guests. Thank you for taking the time to write a review and I hope you would reconsider staying with us to give us an opportunity to change your opinion.
by A verified traveler
Don't stay here save your moneyPosted May 2, 2017 on Hotels
It was a horrible experience do not stay here. The smell in the rooms is horrible and it looks horrible.
Comment from Hotel Management
May 10, 2017 by Reena Shah, Hotel Management
Thank you for taking the time to write a review. We would have loved to have an opportunity to make it right during your stay if you had any issues and let us know. You have not mentioned anything about your reservation. Please inform us about that so we can check into this matter. We have new coverlets, new flat screen tvs, new carpets in the rooms. Could you have had a smoking room reservation?
by A verified traveler
Would not stay againPosted May 2, 2017
Would not stay again Mail desk clerk was rude and on helpful during check-in. Air-conditioner called the room but was very noisy. Not in a good Area of town.
Comment from Hotel Management
May 12, 2017 by Manager, Hotel Management
I am sorry to hear that you were disappointed with the customer service at check in. Your review will be called to the attention of concerned staff and will be reported to our management for corrective measure. Thank you for letting us know. I hope you will stay with us again and allow us to serve you better.
by Amber
Posted May 2, 2017 on Hotels
Every thing was good. Only complaint is the wifi. It barely worked. In and out.
Comment from Hotel Management
May 10, 2017 by Reena Shah, Hotel Management
Thank you for taking the time to write a review. we appreciate your kind words Amber. We are working on the wifi issue with our service provider
by Arlene
Disappointment...Posted Apr 15, 2017 on Hotels
I booked this hotel late almost into the next day me and my kids had no where else to stay. I looked at the rating and apparent hotel appearance. Bad idea. Seems like their where gangs I was afraid for my life. I was told others had left that night because the area was so unsafe. It seems people lived there. This is not a two start hotel. Half of one. This hotel shouldn't be advertise families confide in this site so that hotels are at least safe. Everyone seem to have a gone. Teller said there are shoot outs. I try to get my money back since I had to drive for another hour now 1am and paid double for a last minute place.
Comment from Hotel Management
Apr 17, 2017 by Reena Shah, Hotel Management
I am surprised to see your review and I have tried to search your reservation and could not find it. Could I get more information so I can make sure that you actually did stay with us. Thank you


text:
Reg: $112.94
In Stock: 0 btls
Ships Inmediately
Pre-Arrival: 24 btls
ETA: Pending
Orders placed M-F before 3pm (PST) will ship same day.
Orders placed on the weekend or over a holiday will ship the next business day.
More info
Free storage available
More info
Shipping info
Storage info
2014 Hilt The Vanguard Chardonnay
Chardonnay - 750ML
2015 Cakebread Cellars Chardonnay
2014 Girardin, Vincent Puligny Montrachet Vieilles Vignes
2013 Leeuwin Estate Chardonnay Art Series
2015 Brewer-Clifton Chardonnay Santa Rita Hills
2014 Mayacamas Chardonnay
2014 Domaine Bonneau du Martray Corton Charlemagne
Dear Customer
We are having problems processing your request.
Please contact our sales office between 9 AM and 5 PM (PST) for further assistance at 1.888.859.4637.
Competitive Prices. Especially good with Bordeaux futures. Email offers always tempting.
-Aaron C., March 2017


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You've probably seen the term Internet of Things (IoT) and, if you're like most people, you might have dismissed it as a fad. It's nice to know that, for example, a toaster can be connected to the internet, but businesspeople are rightly interested in why it should be done rather than whether it can be done.
IoT certainly had a rocky start and it's taken some time for genuinely compelling business cases to start to emerge. But with up to a third of businesses already using IoT devices or data, and up to 21 billion connected devices expected by 2020, it's time to get serious about things.
At its heart, IoT is simply about collecting data through sensors and doing something useful with that data.
The sensors themselves can be anything from a simple switch, to a recycled phone handset, to a city-wide network of devices. Temperature, motion, open/shut, light levels, sound, proximity, location, position and orientation – almost any physical event or property can be useful data in the right situation.
Machinery is increasingly being built with IoT sensors baked in, and big players such as Amazon and Google, as well as industry darlings like Adafruit, are lining up to provide the data and analytics backbone.
The benefits vary widely and can be very specific to a business. For example, an IoT mouse trap might seem like an extravagance to most, but to a restaurateur, knowing when their traps have been sprung could save them from a failed health inspection.
To a retailer, knowing when their customers are near a store through the use of beacons and loyalty apps can create opportunities for impulse sales with push marketing. And for those in warehousing or distribution, sensor-based data can be used to optimise stock locations, energy use, routing and many other factors to reduce cost and increase efficiency.
Can you imagine a future where a phone app can guide you to the nearest available street parking space? If you live in Santander, Spain, that future is already here. Smart cities depend on the IoT to deliver useful services to their citizens.
Vineyards can remotely monitor temperatures, receive alerts in the event of frosts, and remotely operate (or automate) smart sprinkler systems that could prevent a lost crop. Does your business depend on critical consumables? There may be a value in monitoring their levels and alerting your suppliers to have them replenished to avoid downtime.
Of course there are many complicating factors such as security and privacy, maintenance and the know-how required to set up the system and the data analytics to gain benefits from it. But these are known, solvable problems. The tech is very accessible and the next generation of consultants are already diving into the IoT at places like CoderDojo using Arduino boards and cloud-based analytics.
As part of your next digital strategy session, give some serious thought to how data about your business could help you optimise it or reduce risk. And if you're looking for business ideas, there are many niches that aren't even discovered yet, let alone filled.
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James Radvan is the Service Delivery Manager at GBST/Emu Design. While he now calls Brisbane home, his software career has taken him to the US, UK and Sweden, in everything from startups to multinationals.
At his happiest building things, he is a coder, project manager, musician, maker, painter and inveterate tinkerer. Having started his own son and daughter on the path to being code ninjas, James can be found on Saturdays mentoring at Chermside CoderDojo.


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Please see flyers attached for more information on each event.
Family Fall Feast – October 13, 2016 Family Fall Feast Flyer
Breakfast With Santa – December 10, 2016 Breakfast With Santa Flyer
Trinkets To Treasures – December 16, 2016 Trinket to Treasures Flyer
Valentines Family Dance – February 9, 2017
Spring Fair – May 26, 2017 Spring Fair Flyer
Fundscrip Fundraiser
The WSA has sent home info on an easy fundraiser. If you buy groceries, gas, clothing, or give gift cards as gifts, this is for you!!! See the many retailers that that give back to Westmount when you order gift cards to use for many things.
Go to www.fundscrip.com
Click: Support Group
Enter group code: FSEDZ3
Westmount School Association Holiday Wreath Fundraiser
Details for the 2016-2017 Holiday wreath orders will be posted in November.
Mabel's Labels fundraising link – labels for the stuff kids lose!
Westmount School and Tanner Transfers (recycling Depot)
Westmount School & Tanners Transfer (Recycling Depot) have teamed up to fundraise & recycle.
It's so EASY!!!!
Here's how:
1. Collect your refundable containers
2. Take them to Tanners Transfer and tell them it is for Westmount School
That's it!!!!
For more information please see the flyer.


text: Seller: hix.antiquitatis (705) 100%, Location: New York, New York, Ships to: Worldwide, Item: 282123264344 Provenance: Ownership History Available, Material: Steatite, Details: Egyptian Inscribed Scaraboid: Fish An ancient Egyptian blue-green glazed steatitie scaraboid in the form of a Nile Perch with an inscribed base. New Kingdom. Ca. 1570-1070 BC. Length: 13 mm. Intact. Formerly in the M. Carvin collection, (Vienna & New York), acquired prior to 1970.#4131GUARANTEED AUTHENTIC AND AS DESCRIBEDHIXENBAUGH ANCIENT ART, NEW YORKMember: Appraisers Association of America (AAA) Art and Antique Dealers League of America (AADLA) Confederation Internationale des Negociants en Oeuvres d'Art (CINOA)See our 'about me' page for our credentials and expertise. All antiquities we handle are authentic and legally acquired. Every piece is accompanied by a complete description with photo and signed guarantee of authenticity.See our web site for more examples of fine ancient art.


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Can you repair Bumper Bars?
Unfortunately we cannot repair Bumper Bars, they are plastic.
Can you repair Refrigerator doors?
Refrigerator doors cannot be repaired with this method.
What if we cannot repair it?
If we are unable to repair the dent, there will be no charge and we will gladly refer you to a quality Panel Shop.
Can I do this myself?
We recommend you do not do this yourself. This skill takes a long time to learn. You can try, but we don't recommend you do. In most cases when the customer has worked on the car previously it raises the cost or in most cases we cannot repair it.


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Today, we'll talk about what happens to the money in your escrow account, whether or not you have to escrow, and what shortages and.
The seller changes their mind, you change your mind, the home is infested with termites or the title has issues. All of these problems and more..
Escrow yhoo home lifestyle -- tour fastEach servicer has its own way of approaching things like the escrow analysis statement, or how to make a payment if you have a shortage. Tell us what you think! All of these questions and more will be answered by watching the following video. BUT, if your reasoning is not justifiable by the contract you will lose your earnest money in order to compensate the seller for the time their home was off the market.
You're guaranteed a rate of return to the mortgage interest rate. Saving for a House. The Company cautions that all forward looking statements are inherently uncertain and that actual performance may be affected by a number of material factors, many of which are beyond the Company's control. We just refinanced and will be making our first Quicken mortgage payment in August. Connect With Us: Email. In some cases, after an escrow analysis is done, you can actually end up with a surplus or shortage in your account. I thought it was because it was coming out of my escrow account. BUT, if your reasoning is not justifiable by the contract you will lose your earnest money in order to compensate the seller for the time their home was off the market, escrow yhoo home lifestyle. Would quicken loans be able to refinance us? We never want to hear our clients have had a less than amazing experience with us. In particular, there is significant regulatory uncertainty with respect to the production and sale of medicinal and recreational marijuana in the United States of America. A reputable attorney will ask you for a open letter becoming to be placed in an escrow account. Trending in Real Estate. In the music video, lead singer Hayley Williams is seen singing alone in many shots. Maximize Social Security benefits. This has created a lot of stress and confusion for me. Generally, the county folks can sometimes be behind what is going on and screwup mailing these reasons date engineer bills to you and can make you fresco .
Escrow yhoo home lifestyle - - travel
Queen Elizabeth will continue her royal duties as scheduled. Follow up with your servicer or lender.


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Let's face it, we all forget things from time to time. If you're like me and never remember to pick up a card, consider us your Valentine's fairy godmothers.
Thanks to Becca from Becca Bliss & Co., we have a free Valentine's card for you! Just click print, fold it in half, and seal with a kiss. If you're looking for a last-minute gift as well, one of her digital prints might be the perfect thing.
If printing seems like too much work (we feel you), here are some cute, shareable options!


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View buddhist Singles in Lakewood
By clicking continue, I agree to receive transactional and promotional emails from Match.com. I understand that I am free to withdraw consent at any time.
By using our site, you agree to the Match.com Terms of Use.
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"I refuse to give into my blues, that's not how it's gonna be, and I deny the tears in my eyes, I don't want to let you see…" – 'King of Wishful Thinking', Go West.
This is a bit of a brain dump, but a mini epiphany hit me as I was sitting on my kitchen floor, watching a batch of Snickerdoodles bake because I had forgotten to set the timer. For months, years, I've told myself I'm not good enough, that I'm below par in every way. In reality, I'm not. I'm capable, I try hard to be kind and tolerant and I'm relatively clever too (I'm no Alan Turing but I'm not thick either), so what's the dealio bruh?
Well, thing is, I am overtly anxious about things. A lot of the time, it's not me, it's the anxiety talking. That's not an excuse, but it is a moment where I might need to be reminded that, actually, that's not me. It can be so overwhelming, so all encompassing at times that I forget who I am without it, the person I have been for years. I might not suddenly snap out of it, there are no magic words to cure it, but there is a healing process. I might seem selfish, self destructive and full of self loathing, and others efforts might seem futile and powerless against all that, but trust me they are not.
I can be so horrifically shy. I spout absolute nonsense just to fill the silence sometimes so it's unlikely I'll share my true self and struggles without feeling like a bit of a twat. I care more for others than I do myself (which sometimes gets me into trouble. Top tip: be more assertive Kate. You're a human not punching bag. Learn to say no). One thing about being on the more anxious side is that I am rather observant. That's not to say I can't be massively dim, my God when I have a momentary lapse in common sense it's a moment to behold. What a gem. I'm observant, not a mind reader or some sort of superhuman. If I notice something is different, I'll try and figure out what it is and do my best to help the situation. Making other people happy and curing any of their blues brings a smile to my face. Seeing other people's joy, regardless of the part I had to play in it, makes my day so much brighter.
It takes time. I have bad days and good days, the same as everyone else. Sometimes, I need to be alone for no reason at all, sometimes I want to go out and party. Sometimes I want to fade into the background and I'll seem upset or angry for no reason, nitpicking everything and seemingly trying to gain some non existent control over my corner of the universe. Sometimes I don't care, I'll go with the flow. I'll speak up, I'll pipe down, I'll just go where the tide takes me. As Princess Fiona says in Shrek: The Musical: "I'm a mess of contradictions in a dress."
In short:
Anxiety, you're a frickin' spoon and I hate you, but that does not mean you win. K? K. Instead, I'm going to try and exude more niceness and warmth. Cynicism may inform me but never lead me. Sadness may touch me, but never linger.
"Shyness is nice, and shyness can stop you from doing all the things in life you'd like to." – 'Ask', The Smiths.


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Join us for our Senior Bible Study "Soul Journers" led by Fr. Rob Northwood.
Meets from 10:15 AM – Noon in the COR Upstairs Fellowship Hall
Overcomers' Meeting in the upper Fellowship Hall at the church at 7:15 PM. This meeting is a 12 step group that helps those who are struggling with addictions of any sort or are in close relationships with those who are.
Newcomers Bible Study meets at Mark and Sally Carico's home at 360 Harlan Street in Bel Air 21014
Using the Bible, Fr. Rob Northwood expounds on the Word of God (currently studying the book of Acts) in a way that is both understandable to new believers as well as challenging for those who have walked with the Lord for many years, with an emphasis on "keeping it real". Childcare is available- please call the Caricos for more information 410-836-9161
Please note that the Wednesday night Bible Studies will not be meeting on the nights that the Healing Service is scheduled.


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Hi everyone -- just a note to say that more eye candy will come up tomorrow and I'm going to try to get back to everyone's delayed email by the end of the night. I'm hacking away at it!
In other news, there's a great old 00 Washburn guit coming up and I've just ordered parts for my Mark IV banjo bass project. There are also several beautiful customer instruments nearing completion and a curious Heberlein-made violin-style mandolin that's pretty stunning up for consignment.


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© 2015 Universal Studios. Partners Privacy Policies Terms of Use Feedback Sign UpMinions Stuart, Kevin and Bob are recruited by Scarlet Overkill, a super-villain who, alongside her inventor husband Herb, hatches a plot to take over the world.Minions is a 2015 American 3D computer-animated comedy film and a prequel/spin-off to the Despicable Me franchise. Produced by Illumination Entertainment for Ever since the dawn of time, the Minions have lived to serve the most despicable of masters. From T. Rex to Napoleon, the easily distracted tribe has Minion Short Movies and mini clips: - Puppy - Orientation Day - Minions Audition - Training Wheel - Panic in the mailroom And moreWatch the movie trailer for Minions (2015) on Movie-List. Directed by Kyle Balda, Pierre Coffin and starring Sandra Bullock, Steve Carell, Jon Hamm and Katy Mixon.Minions - Search for movie plot, trailers, cast and crew, photos, reviews, and tickets online at MoviefoneAll Copyrights belong to Respected Owner. Universal & ILLUMINATION Entertainment, for Fair Use Intended. (Promoting Despicable Me 2 in Cinemas) (Promoting Minions (2015) showtimes and movie theaters. Buy 3D Minions (2015) movie tickets on Fandango.Read the Minions movie synopsis, view the movie trailer, get cast and crew information, see movie photos, and more on Movies.com.
Sabtu, 05 September 2015
Minion Movie
About arief cahya
Author Description here.. Nulla sagittis convallis. Curabitur consequat. Quisque metus enim, venenatis fermentum, mollis in, porta et, nibh. Duis vulputate elit in elit. Mauris dictum libero id justo.


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Joe Girardi said David Ortiz is "probably comfortable" at the plate against Yankees pitching. He has homered in his last three games in Yankee Stadium.
In a move that is certain to fire up the chorus of Yankees fans calling for David Ortiz to get drilled, Joe Girardi admitted on Thursday that Ortiz is "probably comfortable" at the plate against the Bombers.
"Well he's had a lot of success (against the Yankees) and I think you do get feelings against certain clubs," Girardi said on Thursday. "The question was brought to me about making him uncomfortable.
"We moved him off the plate the other day, I don't know if it was the next pitch or two pitches (later), he hit a home run. The bottom line is if you don't make pitches on this guy, he's going to hurt you and he's going to hurt you bad. And we haven't made the pitches on him. And he probably is comfortable because he's had a lot of success against us."
It's been an interesting series for Ortiz and Girardi.
Girardi said he "didn't care" for Ortiz's bat flip after a fifth-inning homer on Tuesday night. On Wednesday, after hitting another homer in another Red Sox win, Ortiz was not interested in revisiting the controversy. He made that clear in an expletive-filled exchange with reporters.
"I don't care what Joe Girardi says," Ortiz said to a New York writer. "Take it like a man. I'm done with that."
Ortiz said he did not flip his bat Wednesday so he could avoid being on the "national news."
"I don't want to have you guys asking me the same questions. I got almost 370 bombs in the big leagues and everybody wants to make a big deal because I bat-flip one of them. (Expletive) that (expletive), man. If I have to make that video on my (expletive), let's see how many bat flips I got on this (expletive). Good night."
Ortiz has hit 364 home runs in his career. Thirty-four have come against the Yankees, a total against one opponent exceeded only by the 39 he has hit against Toronto. And that doesn't count the five home runs he has hit against the Yankees in the postseason, including one of the most dramatic in club history -- the 12th-inning walkoff home run in Game 4 of the 2004 ALCS.
Ortiz has homered in each of the team's past three games against the Yankees, all at Yankee Stadium.
The last Red Sox player to hit home runs in three straight games in the Bronx was Mo Vaughn, back in 1994, according to the Elias Sports Bureau.
Information from ESPN.com's news services was used in this report.


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Family Medicine GP Job, Australia
- Recruiter
- Prospect Health
- Location
- Victoria
- Salary
- Competitive Salary
- Posted
- 22 Jun 2017
- Closes
- 22 Jul 2017
- Ref
- Contact
- International Support
- Role
- Salaried GP
- Contract Type
- Permanent
- Hours
- Full Time
- Industry
- Private
Our client is seeking a family medicine GP's to join their enthusiastic, motivated and expanding medical team across several existing practices in Victoria.
Doctor owned and with four more clinics opening this year you will be working alongside a friendly and supportive group of colleagues which will make your professional journey as smooth and as pain free as possible.
Our client can offer a 12 month contract - 2 x 6 month locum in inner city clinics but their preference would be a two year contract to the right applicant. With a number of UK trained GPs currently working for them our client understands healthcare and doctor's needs. Become part of a team that is dedicated to ensuring its patients stay in the best possible health.
My client is primarily looking for male or female doctors who are trained and have worked in Australia, New Zealand, The UK, Ireland, Canada or Singapore. The ideal candidate will have specialist qualifications from one of these countries and also membership of the appropriate Royal College.
Several locations across Victoria, Australia
Key Information
Key Benefits
What Happens Next
To talk to us in confidence about this opportunity or any other suitable positions, please contact a member of the International division on 01423 850434 or click on the apply button below.
Office Hours Monday-Thursday 9am - 8.30pm Friday 9am - 5.30pm
Not the right job for you? Click here for more International Doctors & Physician Jobs


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Having Fun, Dreaming Big, Always Learning.
Thursday, March 16, 2017
20th Century Open House in the 21st Century? Let's Rethink our Options. By Sheila Schue
This post was written by Sheila Schue, a 3rd grade teacher at Stoneridge Elementary School ( @rcsdstoneridge ). You can follow her on twitt...
7 comments:
Sunday, February 5, 2017
THE Experience at Ron Clark Academy
Our staff with the most passionate and innovative educator ever, Mr. Ron Clark. In August of last year I sent an email to my staff let...
5 comments:
Saturday, January 21, 2017
Flush With Cash
In Donald Trump's inaugural address he stated that our education system is "flush with cash, but which leaves our young and beautiful stu...
8 comments:
Tuesday, January 17, 2017
CHOICE- Are We Preparing our Students for Their Future? by Christi Robertson
This post was written by Christi Robertson, a 4th grade teacher at Stoneridge Elementary School (@rcsdstoneridge). You can follow her on tw...
1 comment:
Sunday, January 8, 2017
Leaders Must Also Teach #leadupnow Guest Post
Here is the link to my most recent post, "Leaders Must Also Teach" that was posted on the leadupnow.com website. Our educational ...
Wednesday, December 21, 2016
No AR, No Big Deal
This post was co-written with Rachael Peck (@rachaelpeck23, you can check out her blog here ). Rachael and I are both elementary school p...
1 comment:
Thursday, August 4, 2016
If We're Going to Have Homework, Let's Do It Better
Homework has always been a controversial subject for teachers and parents, and there are all sorts of opinions: We have parents that wa...
10 comments:
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Committee > UK Committee Member
Dr Sara Wolfson
Dr Sara Wolfson is a Lecturer in Early Modern History at Canterbury Christ Church University (full profile page). Prior to this she lectured in Early Modern British and European history at Manchester Metropolitan University. She completed her AHRC funded PhD at Durham University in 2010 on the female court and household of Queen Henrietta Maria. She is currently reworking her thesis for publication as a monograph, focusing on the political, social and religious roles that Caroline court women played in the period 1625-1669. She has recently published a chapter on the politics of Henrietta Maria's female Bedchamber in Nadine Akkerman and Birgit Houben (eds.), The Politics of Female Households: Ladies-in-Waiting across Early Modern Europe (Leiden: Brill, 2013). Sara's research also focuses on transnational relations between the Dutch Republic and the Stuart crown in 1641-3. This will form part of a wider project that explores the transnational nature of royalism.


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Rating: PG-13
Characters: Sam POV
Genre: Angst
Summary: How Sam went strolling down a dark, dark road.
Spoilers: Everything up to 4x09
Disclaimer: Not mine. Although if it was, things would be going much differently (it's amazing that it's been a year since I first used this disclaimer and yet it does not need to be changed . . .)


text: Although anxiety plays a key role in delusions, its downregulation using specific emotion regulation (ER) strategies has not been investigated. Reappraisal has been shown to be one of the most effective strategies for healthy individuals. However, individuals with delusions might have difficulties in successfully applying reappraisal. This study therefore tests the effectiveness of reappraisal compared to expressive suppression in individuals with varying levels of delusion-proneness.


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If you are fed up with your present job or you are no longer able to do the jobs which you have had for years due to ill health or other reasons then have you considered working freelance? There are lots of freelance business ideas which can quite easily be done with little or no retraining depending on the job. Some of this freelance employment does require some equipment such as freelance photography business you will need camera; photography equipment and the ability to develop the pictures, this can be quite expensive to setup but once you have done this you will have the enjoyment of working for yourself.
Business Resource Center
The Business Resource Center is your resource for business insurance quotes, fast business loans, local business marketing and business credit services.
Recent Posts
- Welcome to our Website
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Question about Canon PIXMA MP830 All-In-One InkJet Printer
Posted by ljharte on
SOURCE: I have freestanding Series 8 dishwasher. Lately during the filling cycle water hammer is occurring. How can this be resolved
a 6ya expert can help you resolve that issue over the phone in a minute or two.
best thing about this new service is that you are never placed on hold and get to talk to real repairmen in the US.
the service is completely free and covers almost anything you can think of (from cars to computers, handyman, and even drones).
click here to download the app (for users in the US for now) and get all the help you need.
Posted on Jan 02, 2017
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Social media is powerful. This is a fact which we all must admit. It can bring someone to fame's doorstep and in the same way strip a person of all their fame. The Internet is so powerful that it has brought careers to an end, soiled reputations and even brought banks to their knees (refers to Chase Bank's collapse ).
It has been a tough couple of days for popular beverage company in Kenya, Daima, famous for manufacturing yoghurt, juice, milk, water and even milk powder. Daima has been the subject of talk and debate on social media after a dis-pleased customer posted a video exposing worms in his Daima branded yorghut.
The video immediately sparked an outrage among Kenyans as some went as far us urging the Consumer Federation of Kenya (Cofek) to investigate the company. According to some observers the whole video was the result of a scam by competitors.
That said, the company has finally responded to the claims in an effort the restore confidence in the brand. In a post on their Facebook page, the company explained that;
"No worms can survive in the healthy accepted levels of acidity in yorgut…..the yorghut in the video has discoloration and coagulation which can be as a result of seal tampering and long exposure to high tempratures."
Well we all know it's very hard to earn trust back once lost, let's hope Daima will be convincing enough to Kenyans.


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Without our generous supporters and volunteers, there would be no K9 Friends.
Because K9 Friends is a voluntary run, non profit making shelter we rely on the good will of others to help us survive.
There are many ways you can help and support our work, including volunteering, dog walking or fostering a dog. You can help financially by becoming a corporate sponsor, sponsoring a dog, sponsoring a kennel or make a one-off or regular donation.
Payment methods
|Deposit a cheque at any Emirates NBD ATS or place a transfer to the K9 Friends bank account as per details below
|Account Name: K9 Friends
Bank: Emirates NBD Bank
Account No: 101 413 793 1801
Umm Suqeim Branch, Dubai UAE,
P.O. Box 777
Dubai United Arab Emirates
SWIFT Code: EBILAEAD
IBAN No: AE61 0260 00 101 413 793 1801
|Please mail any cheque made payable to K9 Friends to our address:
K9 Friends, PO Box 72741, Dubai, UAE,
|You can visit our office between working hours. Please call +971(0)48878739 for more information.
Payment can be made cash or cheque.
If you feel you are interested in adopting REX, please call +971 (0) 48878739.
During this call, you'll be asked to complete a simple questionnaire and thereafter be able to book an appointment to visit the shelter.
We have dogs of all ages, colours, shapes and sizes all with different personalities and temperaments. Each dog is assessed to find out what they are like and what sort of home, lifestyle and environment would suit them best. Each and every animal is considered individually and matched at point of interview with the most suitable owner.
Our homers have a good knowledge of our dogs and will advise you to the most suitable dogs for your situation.
How much will it cost?
|These costs cover the following treatments, which are carried out by K9 Friends:
|*Note: Regrettably,we have no debit/credit card facility and are only able to accept cash or cheques.
|After you have been given your appointment; please bring with you:
|*Please note that you have to be 21 years old and the home/lease owner.
|* Note: Visits are by appointment only. Please call +971(0)48878739.


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Legendary National Hockey League goaltender Patrick Roy shocked the world when he quit his position as head coach of the Colorado Avalanche, but now we may have a clearer picture of why he made that decision.
On Tuesday during a segment for Insider Trading TSN's Bob McKenzie revealed that many suspect Roy was motivated by what he saw in his future if he remained behind the Avs bench.
"There are many that believe that this Avs plummet to the basement is precisely the reason why head coach Patrick Roy resigned in the summer, rather than continue to be a part of it. He knew this was likely coming, and if this came with him behind the bench the logical move would be.... to let the coach go."
If McKenzie is right, Roy may have wished to avoid being made a scapegoat for a losing team and there were signs Roy saw this coming early last season. Rumors of disagreement between Roy and general manager Joe Sakic over personnel decisions persisted and it seems Roy believed the team was being steered in the wrong direction. Given the performance from the club this season it seems he may have been correct, and chose to go out on his own terms as a result.