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Series: Reproductive Biology of Invertebrates Volume: 11
337 pages, diagrams
About 95 per cent of all known animal species are invertebrates. Knowledge of their sexual, reproductive and developmental biology is essential for the effective management of species that are economically useful to man, or are harmful to him, his crops or livestock. This book contains chapters by leading experts in the field. It covers much of the up to date research in an informative and highly useful fashion. It also covers all parts of recent progress in vitellogenisis.
...a trove of information...central message is clear...important and worth reading... (Entomologia Generalis, Vol 109(12), Dec 2003)
Preface to the Progress Series. Preface to Volume XI. Obituary. Contributors. Microorganism induced Parthenogenesis (H. Braig, et al.). Clonal or Sexual Reproduction in Parasites? Recent Advances in Molecular Understanding (D. Rollinson and J. Stothard). Geographic Parthenogenesis in Terrestrial Invertebrates: Generalist or Specialist Clones? (E. Parker Jr). Senescence or Rejuvenation in Asexual Metazoans (D. Martinez). Asexual Reproduction in the Hydrozoa (Cnidaria) (F. Boero, et al.). Genetic Mosaics and Chimeras (R. Hughes). Resource Allocation in Asexual Invertebrates (V. Forbes). Astogeny and Allometry of Modular Colonial Organisms (H. Lasker and J. Sanchez). Population Processes in Modular Benthic Invertebrates (R. Karlson). Clones and Metapopulations (B. Okamura, et al.). Subject Index. Species Index.
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DR. K.G. ADIYODI, formerly Professor of Physiology and Dean, Faculty of Science, Calicut University, Kerala, India and Vice Chancellor, Cochin University of Science and Technology, Kochi, is now Public Service Commissioner to Government of India, New Delhi. A distinguished invertebrate reproductive biologist, who gave the discipline of invertebrate reproductive biology a global distinctiveness and identity of its own, Dr. K.G. Adiyodi is Founder Secretary of the International Society of Inverebrate Reproduction, Founder Editor in Chief of the International Journal of Invertebrate Reproduction and Development, and Founder President of the Indian Society of Invertebrate Reproduction. DR. RITA G. ADIYODI, formerly Rhodes Visiting Fellow, Somerville College, Oxford (1976 78), is Professor of Zoology at Calicut University. She served as President of the Crustacean Reprobiology and Aquaculture Bureau of India and as Vice President of the Indian Society of Invertebrate Reproduction. Dr. Rita Adiyodi represented India on the International Committee of Comparative Endocrinology. The Adiyodis have worked extensively, over the past three decades, on the endocrinology and physiology of growth and reproduction of arthropods, chiefly crustaceans. DR. ROGER NEVILLE HUGHES is Lloyd Roberts Professor, Professor of Zoology, in the School of Biological Sciences, University of Wales, Bangor. While maintaining wide interest in evolutionary and behavioural ecology, he has focussed particularly on the biology of clonal animals. By adopting the bryozoan Celloporela hyalina which can be propogated sexually and asexually, as a model experimental organism, he is able to investigate a range of fundamental problems including gender allocation in simultaneous hermaphrodites, the effect of temperature on body size and the contribution of cryptic speciation to marine diversity.


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General Information and Sites on Public and Private Life
Maps and images from "on high"
Public Life
Private Life
Aliens view of classical culture.
Ellen Harvey's new project is a glimpse into the world of the distant future. Human civilization having long-since come to an end, the earth is populated now only by ruins, ripe for archeological interpretation by visitors from another planet.
Most immediately striking to these alien historians are the remains of the classical and neo-classical buildings that seem to have taken root in every corner of the globe. Attempting to make sense of what they find, Harvey's aliens immediately mine the potential of one of the greatest neo-classical cities—Washington, D.C.—as a tourist destination. The Alien's Guide to the Ruins of Washington, D.C. is the result. A tour of America's capital city through alien eyes, the exhibition's centerpiece is a self-guided map of Washington's landmarks. Available for pick-up at the Corcoran's alien visitor center as well as other locations throughout the city,the Alien's Guide contains reconstructions and interpretations of such sites as the White House, the World War II Memorial, and the U.S. Capitol.
The rest of Harvey's exhibition follows the aliens' attempts to interpret their findings. One of the Corcoran's galleries is devoted to educating the alien children about the classical style around the globe, following its roots as a symbol of democracy in ancient Greece to its subsequent use in the service of empire builders, fascists, Stalinists, museums, banks, and post offices. Seduced by the architecture's power themselves, the aliens have erected a spaceship in the neo-classical style, on view in the Corcoran's rotunda.
The Alien's Guide investigates the abiding influence of classicism, the dissemination of style, and the language of power. Humorous, unexpected, and eye-opening, it sheds light on a world at once familiar and strange. - See more at: http://www.corcoran.org/aliensguide#sthash.8oqZoKPJ.dpuf
Discussion of passages in Thorton's Introduction

subset: commoncrawl


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I know some of these are dungeons, but they are notable mentions!
1) ToC without a question. Just lame design except for the final boss
2) Maraudon (though the end is pretty and fairly unique boss)
3) AQ40 - just a pretty confusing and generic place until the end boss, tbh
4) Wailing Caverns - confusing and far too large for its level.
I'm not a fan of dungeons on the LFG system that take an insane amount of time to run back in, e.g. WC, Maraudon or BRD (which I personally think is very fun until some noob causes everyone to wipe and it takes 10mins for everyone to figure out where the entrance is and actually manages to find their way to their corpse).


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I think I've found what works for me to prepare for bed and fall back to sleep if I ever wake up during the night: meditation!
I haven't been consistent with it, but I've discovered that doing mediation exercises right before bed has helped me fall asleep much faster than I usually do. I also stay asleep longer. After watching a few videos from last year's Beyond Tired participants, and seeing how it worked for them, I decided to go ahead and make it a permanent part of my pre-bedtime activities. I've also found a few stretching exercise videos online, and have a few audio recordings I already listen to, so I'll keep those in rotation. I just hope I can clear my head enough to actually benefit from it!


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123Re: "Getting characters from an screen and putting them in another one"
Expand Messages
- Aug 7, 2002If it is something like an edit control, you should be able to use
WMGetText to obtain the text and WMSetText to display it on another.
--- In perlguitest@y..., "hellarleo" <hellarleo@y...> wrote:
> Hi Members!
> I need to write an script which need to copy a little text at fixed
> position of an Windows application screen and paste it to another
> Anyone knows how may a do it?
> Best Regards.
- << Previous post in topic Next post in topic >>


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Couple FedExes Their Toddler 500 Miles Across The Country After A Blizzard Grounds All Flights
It goes without saying that most parents would do anything to ensure the safety of their children. This is especially true in the case of a medical emergency.
Every parent knows that getting their child to proper medical care is one of their most important jobs… even if that means using rather unconventional methods.
When a blizzard prevented the Faris family from flying out of Memphis, Tennessee, when their two-year-old needed a liver transplant, they had to resort to outlandish methods to get her to Chicago—and fast!
Wow, you don't really expect major companies to stick their neck out for the little guy like that. It just goes to show that when people band together, they can achieve anything!
Share this story of good will with your friends below!


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Would you like to get your GED in Elkhart TX? The General Education Development (GED) examination is for adults who do not have their high school diploma. The certificate that you receive upon passing the Texas GED examination is accepted as an equivalent credential to a high school diploma by employers and colleges across the United States.
The GED exam covers basic skills that students are taught in high school. Subjects taught in GED classes include reading, writing, math, science, and social studies. Those are the subject areas that make up the General Education Development (GED) examination in Texas.
Usually GED programs in Elkhart TX are offered at:
- Elkhart Literacy Centers
- Elkhart Libraries
- Elkhart Colleges
- Elkhart Workforce Learning Centers


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"Our economic recovery will be largely dependent on smart investments in America's small businesses,†said Rep. Sanchez. "This bill will help local entrepreneurs start, build, and grow their businesses and, in the process, strengthen Orange County's economy. It's a surefire way to create new jobs and new opportunities here at home.â€
Orange County - Local
Seth Meyers Highlights Dana Rohrabacher's Defense of Russia and his Anti-Science Beliefs, Dr. Hans Keirstead Responds


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Thomas M. Sterner has studied Eastern and Western philosophy and modern sports psychology and trained as a jazz pianist. For more than twenty-five years, he served as the chief concert piano technician for a major performing arts center. He prepared and maintained the concert grand piano for hundreds of world-renowned (and demanding) musicians and symphony conductors, and his typical workday required constant interaction with highly disciplined and focused artists. At the same time, he operated a piano re-manufacturing facility, rebuilding vintage grand pianos to factory-new condition.
Tom has parlayed what he learned from his profession into a love of practice. He is an accomplished musician playing several instruments, private pilot, student of archery, and avid golfer. Practicing these activities fills his spare time. He has also worked in the sound and video arts fields as a recording engineer, audio and video editor and processor, and composer. He has produced a radio show about The Practicing Mind and continues to teach his techniques to businesspeople and at sports clinics. He lives in Wilmington, Delaware.
Here is part 2 of my interview of him.
To read Part 1, please click here.
Sterner:I always wanted to be a writer and as I mentioned above I was encouraged to do so from grade school on. I went in a different direction in high school when I became interested in composing (which is just musical writing). I started out in song writing but then as my musical skills advanced I became more interested in jazz improvisation and orchestral composing. Growing up I was very undisciplined in all my efforts. I repeatedly got very excited about trying something new but then usually lost momentum pretty quickly and quit on my efforts. I fell short of accomplishing many of my own goals. Because I was very aware of my internal dialog I would pay attention to my-self talk and notice how this pattern of behavior made me feel which was pretty poor. I lacked self-confidence and I felt I had no real power if I couldn't chose a goal and see it through.Around my senior year in high school I decided I really needed to change that aspect of my personality but I didn't know how. When I started studying Eastern Thought in college I began to feel that perhaps I had a way out of my lack of discipline. Part of this came from the realization that I was almost never in the present moment and that was affecting my experience of every endeavor I undertook.
By the time I hit my late twenties I was constantly being referred to as extremely disciplined which at first seemed very odd to me but after looking at what I had accomplished I realized it was true.
Moving into my thirties I started playing golf seriously and I became fascinated with peak performance studies partly because their findings mirrored what Eastern Thought had been saying for thousands of years. It was just being rephrased in modern western terms. I began reading everything I could get my hands on and applying all that information to learning golf. This created an environment where I moved quite quickly. I was told by more than one PGA professional that they had never met a student like me which was quite a compliment.
I really wanted to better understand what I had learned, how I had learned it and how I had implemented it into the way I processed my day. I also wanted to express that understanding to others and hence The Practicing Mind began to take shape.
Morris: Were there any head-snapping revelations while writing it? Please explain.
Sterner: Not really. most of my revelations happened pretty quietly and without fanfare before actually writing the book because they were learned by… I hate to say this, practicing ideas over and over again to see how they worked. The one notable epiphany I can state that occurred before I wrote the book is the one I wrote about regarding trying to become a "good" musician. Without repeating that whole section I will just say that coming to the understanding that there was no place I needed to "get to" in music or even could get to as in being a perfect musician was a revelation and so freeing for me. I stopped feeling a sense of incompleteness as a musician and the self-imposed pressure to see constant measurable improvement ceased to torment me. I realized that the real joy I was seeking was in the infinite expansion of my skill level and that expansion was happening in every moment of every repetition. There was no wasted effort, only growth and that understanding gave me the perspective that the same "process" that I had interpreted for so long as a never ending struggle and at times boring was now something I treasured. That perspective immediately began to pervade every endeavor I undertook and in that sense was life changing.
Morris: To what extent (if any) does the book in final form differ significantly from what you originally envisioned?
Sterner: The only real difference was that originally I saw the book as being only for musicians or people who wanted to become a musician. In my business I saw so many people both young and old begin and quit the journey of learning a musical instrument. I felt I could have a positive impact on that with what I had learned. As I began writing the book I realized that I used the same information all day long in everything I did. It was just who I was at that point so the book had to be about life in general.
Morris: What are the defining characteristics of a Practicing Mind?
Sterner: The Practicing Mind is quiet, It is not silent though because any activity contains thoughts. It is absorbed in the present moment. This comes from an awareness of the goal but at the same time a detachment from the moment it will be reached. Attachment to the goal which always pulls us out of the present moment comes from a false sense that we are incomplete in this moment, a sense of there is a perfect place and I am not there. That place is outside myself, in the future, not here and not now and once I reach that place this feeling will go away and I will be happy. It's odd that no matter how many times we are shown that this mindset is a very unproductive paradigm we continue to cling to it.
Morris: For decades, K. Anders Ericsson and his colleagues at Florida State University have conducted research on peak performance. The results thus far suggest that, with rare exception, peak performance requires at least 10,000 hours of "deliberate" (i.e. disciplined, focused, intense, and iterative) practice under strict, expert supervision. Such an investment of time and effort does not [begin italics] guarantee [end italics] peak performance, Ericsson acknowledges, but is almost impossible to achieve without it.
Your own thoughts about all this?
Sterner: What I notice immediately is the focus on numbers which can create a paradox. Speaking from my perspective that kind of information though it may be interesting and true, knowing it does not serve to create or inspire peak performance. What I mean is that if you say to someone in order to do this "well" one thing you should understand is that you will have to do it at least 10,000 times under strict supervision, that immediately sets up an attachment to the "goal" of 10,000 repetitions which pulls you out of the process of just being in this moment and repeating whatever you are working on. Thoughts like "I have only done this oh gee I don't know, maybe 350 times and I have so far to go before I develop and proficiency" Or "I have done this over 4000 thousand times. I should be better at this by now" are almost inevitable.
I recently finished a lecture at a music university and that was one of the comments a faculty member shared with me. She had a student who was repeatedly in her office in tears because she (the student) felt like she was working daily at their art and not improving. The faculty said I couldn't get her to let go of the whole concept of so many repetitions will equal this or that. Just immerse yourself in the process of repeating.
I'm also not sure how to define an "expert". I studied golf under three different "experts". All had the same credentials but only one was able to really communicate to me in a manner that worked and so I progressed. The many repetitions I made with the other two coaches did not produce the same progress as fewer repetitions with the one coach did. The same was true in my music training as I studied under several people.
Certainly one of the most important parts of that information is the word "deliberate". To be deliberate to me means that you are working in the present moment with a specific intention and that will definitely speed the brain's learning curve.
Morris: Why did you select the journey metaphor when explaining the process by which to develop a practicing mind?
Sterner: That's because the "journey" IS goal. I am a sailor and a fellow sailor once said to me "when you get out of the marina you have reached your destination". That's because the process of sailing is WHY you are there. The arbitrary "destination" for that day's sail is just to give you some place to go so you can experience the "process of sailing"…reading the wind, watching the sunlight on the sea, challenging and increasing your skills. I have said this before. You can curse the speed of the boat as not moving fast enough or relax and enjoy the experience that is all around you. The 50 miles distance you will travel to the port stays the same. It's your choice.
Morris: What have been the most valuable lessons that you've learned from playing golf that you could apply when engaged in other activities and facing other challenges?
Sterner: The absolute beauty of golf is that it is a perfect metaphor for life. In a single round of golf you can experience so many things. Disappointment, fear, anger, embarrassment, elation, self-doubt and on and on are waiting for you. They are all part of a round of golf and anyone who has played the game knows this. Because of this Golf offers you the opportunity to both learn to be aware of how you are processing your experiences moment to moment and how to increase your skill level at handling difficult situations all within the safety of a "game" that only asks you for 4 to 5 hours of time before it lets you off the hook.
Morris: In turn, what have been the most valuable lessons that you've learned away from the golf course, driving range, and putting green that have helped you to become a better golfer?
Sterner: Well for me golf and life are pretty interchangeable in terms of what they demand from you to succeed and what they offer you in return. So I routinely take situations in my life such as not paying attention to what I am doing and work on that during my round of golf. In a case such as that I will say my goal in this round is to be fully present during the process of each shot from tee to green.
It sounds like "well obviously you want to do that" but I could say the same thing about paying full attention to someone who is speaking to you and how many times do we really do that. Golfers don't realize how much their mind wanders until they try to stay aware of it and to stay present.
I also try to take the "4 S words" to my golf game at times. In other words I will often tell myself that I am going to work on only one aspect of my game in a round instead of trying to play a great round with a low score. This can be very difficult to do because the temptation is to become attached to the score and want to do everything well in the round. It requires discipline and detachment from the score to let go and focus on one weaker aspect of the game for the entire round in order to evolve my game on the whole.
Morris: For those who have not as yet read The Practicing Mind, you include an especially interesting story about a young, immature, and undisciplined chariot driver. What's the point of this story? To what extent (if any) is this story autobiographical?
Sterner: The point is to understand that we are not our thoughts. We experience all of our thoughts but for most of us we only direct a few. I ask people to sit with their eyes closed for just two minutes and STOP thinking. They find that they can't do it, even for such a short time. So the mind will go into search mode and look for something to think about even when YOU are willing it not to. So who is really in control? Most of us are not the chariot driver with the reins in hand directing the power and energy of the horses (our mind) to process what we want but instead get carried through the day with our mind firing off thoughts that are responses to the circumstances around us. Learning to be aware of our thoughts through practices such as meditation gives us at least the opportunity to have the privilege of choice.
Morris: Your approach to "moving through life" changed significantly in your early-20s. Please explain.
Sterner: I think what happened in my early 20s was that I began to gain both momentum and clarity in my effort to transform myself from being a creative but somewhat scatterbrained individual into someone who was in control of my creative energy. Someone who was focused and able to "aim" his consciousness in a direction and know it was going to stay there
Morris: You cite a paradox at the beginning of Chapter 2: "The problem with patience and discipline is that developing each of them requires both of them." Why did you cite this paradox?
Sterner: That came from one of my contemplative walks I try to take daily. I felt it might inspire readers in that it's a two for one meaning whichever one you chose to work on you can know you are developing the other simultaneously.
Morris: Please explain the meaning and significance of the title of Chapter 2, "Process, Not Product."
Sterner: That was meant to be a sort of mental trigger for one to ask oneself when one is feeling impatient with anything. Am I in the process of "achieving" this task or am I "attached" to the future point in time when the product the task is meant to achieve will be realized. It is fundamental to a mindful mindset in anything. I have actually been asked to sign books with just that phrase as if to punctuate it.
Morris: What are the "few simple rules" to creating a Practicing Mind? Which of them do most people find most difficult to follow? Why?
Sterner: The "flow" of a Practicing mind is made up of several components that are not only intertwined but interdependent. To begin with you must learn to be in the present moment. You can't do that without an awareness of when you are NOT in the present moment. So we always must begin with "awareness of our thoughts" which is cultivated through a meditative practice whereby you quiet your mind and learn to notice your thoughts.
Because developing any skill (including learning to be in the present moment) takes time you must let go of the goal and release your attachment to it. Otherwise you misuse the goal and it creates a sense of struggle and impatience.
The Practicing Mind does not judge but it does analyze. Judging occurs in the mind after the subject has been analyzed. In the context of skill development judging leads to unproductive self- talk. "This is good, this is bad, this is taking too long, I should be better at this by now" etc. all create distracting mental chatter which steals our energy and certainly does not increase the speed of our skill development or shorten the distance to the goal.
The Practicing Mind "knows" that perfection is here "now" in this moment, in the process of becoming, of learning, of evolving. Again it is not some place we "get to". This I feel can be the hardest to hold on to because virtually all of marketing works on the principle that we are incomplete and need this thing or this circumstance to feel relief from the sense of incompleteness. The paradigm is fed to us all day long in so many ways and if you are not "aware" of it you are easily manipulated and will succumb to its influence.
Morris: When is "present-minded awareness" most helpful? Please explain?
Sterner: If I had to pick a specific circumstance it would probably be in in highly stressful situations. That's why professionals such as pilots and emergency response people are taught procedures they can fall back on when they find themselves in fearful or upsetting situations. I once came upon a terrible car accident where the car had flipped upside down, the mother was thrown from the car and her child had been thrown up on the dashboard and was pinned against the windshield. In a situation like that a mind that wants to run everywhere is very unhelpful. Having a mind that is totally present and focused (meaning able to analyze the situation without a lot of side chatter from emotions) will be operating with maximum clarity and efficiency which is exactly what the situation demands.
Morris: How to resist the temptation for instant gratification?
Sterner: I can only speak to this from my own experience. Growing up there were many things I wanted, even felt I needed. Most of them I ended up with. But the feeling never went away. It just moved on to the next thing which made me feel like "if I just had this or that now I would be so happy". My awareness of the endless repetitive cycle of feelings I associated with instant gratification eventually drove me to just let go of it. When you get to the point where you see the futility of that thought process, you see that the thirst for instant gratification is unquenchable, it loses its power and influence on you. Then you begin to experience the joy of just being immersed in the process of working toward your goals, immersed in the moment to moment act of achieving them. Crossing the finish line becomes almost anti climatic.
Morris: In Chapter 6, you discuss the "Four 'S' Words." What are they and what is the specific significance of each?
Sterner: The four "S" words are Simplify, Small, Short and Slow. The power they offer is that the act of engaging each one not only pulls us back into the present moment and into being process oriented but they offer us a way to build stamina in sustaining that mindset. For example try to do something really slow. It is very difficult to do without focusing on the process. Walking very slowly takes intention and willpower because the mind is saying "oh I've known how to do this for years, so let's pick up the pace."
If I can use the golf swing as another example…learning a fluent repeatable good golf swing is done by simplifying a rather complex set of movements into small parts each of which are practiced individually and then strung together like a train. There are also studies that show that the brain's quality of focus in learning a skill such as this only last so long. I don't recall the exact time limit but I once had a conversation with a guy who had worked at Pinehurst regarding long and short intervals of practicing a new skill. He told me they had conducted brainwave studies which showed that after so many swings during the learning process the brain sort of timed out and subsequent swings were not nearly as productive in training the mind. The point is that when we simplify learning or accomplishing any task by breaking it into small segments, intentionally slowing down and working for shorter intervals we learn more efficiently.
Morris: Please explain the "Do, Observe, Correct" technique for meditation.
Sterner: DOC is simply an acronym I came up with to illustrate learning non-judgment. If you watch a basketball player shooting foul shots, he/she looks at the hoop which feeds back information to him. He takes the shot and observes the result of his actions and then he corrects based on the feedback. It's all so simple. He does, he observes, he corrects. Internal dialog such as "I can't believe I missed that left, my percentages tonight are terrible, we needed that point" and on and on have nothing to do with increasing the chances of making the next shot. Instead, they begin the flow of confidence robbing emotions which as they say "anchor and install" these emotions into a memory which then need to be overcome in the future.
Morris: How specifically can this technique help to clarify issues as well as alleviate tensions and pressures?
Sterner: Clarity and reduced tension are a natural result of stopping the thought process after analysis and before judgment occurs.
* * *
To read Part 1, please click here.
Tom cordially invites you to check out the resources at this website:
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[…] read Part 2, please click here. * * * Morris: Before discussing The Practicing Mind in Part 2, a few general […]


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Wednesday, August 18, 2010
Today, DC Court of Appeals affirms that electronic or internet "church" does not meet the definition of a church for tax purposes. This affirms the IRS test that the organization must have regularly conducted worship services where the attendees are physically present at the same location. Basically, I am glad the court affirmed a position I have been taking for several years.
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National Pro Fastpitch is wishing all of our families, friends, athletes, teams and alumni a speedy recovery from Hurricane Harvey and Irma!
Commissioner Allan H. (Bud) Selig, National Pro Fastpitch (NPF) Commissioner Cheri Kempf, and Don Hooton of the Taylor Hooton Foundation (THF), jointly announced today that NPF and The Taylor Hooton Foundation are partnering to educate fans of women's softball about the dangers of steroids.
The Chicago Bandits had everything going.A four run first inning with three home runs, two more blasts in the third
inning and Jessica Sallinger had a perfect game going into the fourth
Savannah Long scored from third base on a seventh-inning wild pitch to push the Philadelphia Force to a 3-2 win over the Rockford


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Getac ADD 2ND RJ-45 TO S400G3 (S-RJ45)Item#: 13989575 | Model#: S-RJ45
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text:
The Reserve Bank of India has no information of bank accounts in which a large amount of money have been deposited between November 8 to December 30 last year i.e. post demonetisation.
This came into limelight when Chandrashekhar Gaud, an activist from Neemuch district of Madhya Pradesh asked a query under the Right to Information Act.
Mr. Gaud said, "In reply to my RTI application, the Department of Currency Management of the Central bank on February 17 said it did not have the figure of bank accounts in which more than Rs 2.5 lakh were deposited in demonetised notes of Rs 500 and Rs 1,000."
The query also revealed that RBI is unaware of a number of bank accounts in co-operative banks with such deposits.


text:
Dr Afaf El-Sagheer
Afaf studied chemistry at Suez Canal University (Egypt). She did research for her PhD at Southampton University with Professor John Mellor then moved back to Egypt to become a lecturer. She was recently promoted to Professor at Suez University. Afaf is now working with Prof Tom Brown in Oxford investigating the applications of oligonucleotides in biology. Her current work is focused on the use of click chemistry to assemble novel modified DNA and RNA constructs and on new methods of DNA synthesis.
57 Papers
Template-directed oligonucleotide strand ligation, covalent intramolecular DNA circularization and catenation using click chemistry
(21), 6859-6864, 2007.J. Am. Chem. Soc. 129
Synthesis of alkyne and azide modified Oligonucleotides and their cyclisation by the CuAAC (Click) Reaction
2008.Curr. Protoc. Nucleic Acid Chem.
Synthesis, Serum Stability and Cell Uptake of Cyclic and Hairpin Decoy Oligonucleotides for TCF/LEF and GLI Transcription Factors
(4), 367-372, 2008.Int. J. Pept. Res. Ther. 14
A very stable cyclic DNA miniduplex with just two base pairs
(1), 50-52, 2008.ChemBioChem 9
Rapid and efficient DNA strand cross-linking by click chemistry
(8), 1280-1285, 2008.ChemBioChem 9
DNA Polymorphism as an Origin of Adenine-Thymine Tract Length-Dependent Threading Intercalation Rate
(44), 14651-14658, 2008.J. Am. Chem. Soc. 130
Nucleic Acid Base Analog FRET-Pair Facilitating Detailed Structural Measurements in Nucleic Acid Containing Systems
(12), 4288-4293, 2009.J. Am. Chem. Soc. 131
Synthesis and Polymerase Chain Reaction Amplification of DNA Strands Containing an Unnatural Triazole Linkage
(11), 3958-3964, 2009.J. Am. Chem. Soc. 131
Click chemistry with DNA
(4), 1388-1405, 2010.Chem. Soc. Rev. 39
Factors influencing hairpin oligonucleotide cyclization by the uncatalyzed alkyne-azide cycloaddition (AAC) reaction
(8), 1599-1607, 2010.Pure Appl. Chem. 82
A new fixation strategy for addressable nano-network building blocks
(21), 3714-3716, 2010.Chem. Commun. 46
New strategy for the synthesis of chemically modified RNA constructs exemplified by hairpin and hammerhead ribozymes
(35), 15329-15334, 2010.Proc. Natl. Acad. Sci. U.S.A. 107
Functionalized Nanostructures: Redox-Active Porphyrin Anchors for Supramolecular DNA Assemblies
(9), 5037–5046, 2010.ACS Nano 4
Rapid chemical ligation of oligonucleotides by the Diels–Alder reaction
(1), 232-235, 2011.Org. Biomol. Chem. 9
Characterization of photophysical and base-mimicking properties of a novel fluorescent adenine analogue in DNA
(10), 4513-4524, 2011.Nucleic Acids Res. 39
Improved synthesis of 5-hydroxymethyl-2'-deoxycytidine phosphoramidite using a 2'-deoxyuridine to 2'-deoxycytidine conversion without temporary protecting groups
(4), 1181-1184, 2011.Bioorg. Med. Chem. Lett. 21
Hydroxylation of methylated CpG dinucleotides reverses stabilisation of DNA duplexes by cytosine 5-methylation
5325-5327, 2011.Chem. Commun. 47,
Fast Copper-Free Click DNA Ligation by the Ring Strain Promoted Alkyne-Azide Cycloaddition Reaction
6257-6259, 2011.Chem. Commun. 47,
Biocompatible artificial DNA linker that is read through by DNA polymerases and is functional in Escherichia coli
(28), 11338-11343, 2011.Proc. Natl. Acad. Sci. U.S.A. 108
Efficient RNA synthesis by in vitro transcription of a triazole-modified DNA template
(44), 12057-12058, 2011.Chem. Commun. 47
Structure and Dynamics of Triazole-Linked DNA: Biocompatibility Explained
(52), 14714-14717, 2011.Chem. Eur. J. 17
Click Nucleic Acid Ligation
A6, 2011.Nucleic Acid Therapeutics (formerly Oligonucleotides) 21,
Towards Dark Quencher Based Real Time DNA Sequencing
(3), 611a-612a, 2010.Biophys. J. 98
Fixation of Self-Assembled DNA Nanostructures by Simultaneous Multicenter Click Chemistry
(3), 658a, 2010.Biophys. J. 98
The First All-Nucleobase Analog FRET Pair
(3), 582, 2010.Biophys. J. 98
Click Nucleic Acid Ligation: Applications in Biology and Nanotechnology
(8), 1258-1267, 2012.Acc. Chem. Res. 45
Fast and efficient DNA crosslinking and multiple orthogonal labelling by copper-free click chemistry
2012.Chem. Commun.
Assessing the biocompatibility of click-linked DNA in Escherichia coli
2012.Nucleic Acids Res.
Tension induces a base-paired overstretched DNA conformation
(38), 15179-15184, 2012.Proc. Natl. Acad. Sci. U.S.A. 109
Kinetics of Diffusion-Controlled DNA Hybridization in Lipid Monolayer Films Determined by Single Molecule Fluorescence Spectroscopy
(1), 308-315, 2013.ACS Nano 7
The Structure of FemXWv in Complex with a Peptidyl-RNA Conjugate: Mechanism of Aminoacyl Transfer from Ala-tRNAAla to Peptidoglycan Precursors
(28), 7278-7281, 2013.Angew. Chem. Int. Ed. 52
Solid phase click ligation for the synthesis of very long oligonucleotides
6959-6961, 2013.Chem. Commun. 49,
Copper-free click chemistry as an emerging tool for the programmed ligation of DNA-functionalised gold nanoparticles
Combined nucleobase and backbone modifications enhance DNA duplex stability and preserve biocompatibility
253-259, 2014.Chem. Sci. 5,
Structural insights into how 5-hydroxymethylation influences transcription factor binding
1794-1796, 2014.Chem. Commun. 50,
Transcription of Click-Linked DNA in Human Cells
(9), 2362-2365, 2014.Angew. Chem. Int. Ed. 53
Force-induced melting of DNA—evidence for peeling and internal melting from force spectra on short synthetic duplex sequences
(12), 8083-8091, 2014.Nucleic Acids Res. 42
Reverse transcription through a bulky triazole linkage in RNA: implications for RNA sequencing
7597-7600, 2014.Chem. Commun. 50,
Enzymatic Incorporation and Fluorescent Labelling of Cyclooctyne-Modified Deoxyuridine Triphosphates in DNA
2014.Bioorg. Med. Chem.
Highly Sensitive DNA Sensor Based on Upconversion Nanoparticles and Graphene Oxide
2015.ACS Appl. Mater. Interfaces
Azide and trans-Cyclooctene dUTPs: Incorporation into DNA Probes and Fluorescent Click-Labelling
Click DNA and RNA ligation for new biocompatible nucleic acid backbone mimics
10-17, 2011.Collect. Czech. Chem. Commun. 12,
A triazole linkage that mimics the DNA phosphodiester group in living systems
(4), 429-436, 2015.Q. Rev. Biophys 48
Reversible Ligation of Programmed DNA-Gold Nanoparticle Assemblies
(29), 9242-9245, 2015.J. Am. Chem. Soc. 137
Programming the assembly of gold nanoparticles on graphene oxide sheets using DNA
9379-9384, 2015.J. Mater. Chem. C 3,
New Technologies for DNA analysis-A review of the READNA Project
(3), 311-330, 2016.N. Biotechnol. 33
Efficient enzymatic synthesis and dual-colour fluorescent labelling of DNA probes using long chain azido-dUTP and BCN dyes
2016.Nucleic Acids Res.
Stable End-Sealed DNA as Robust Nano-rulers for In Vivo Single-Molecule Fluorescence
2016.Chem. Sci.
An autonomous molecular assembler for programmable chemical synthesis
2016.Nat. Chem.
Combination probes with intercalating anchors and proximal fluorophores for DNA and RNA detection
2016.Nucleic Acids Res.
2'-Alkynylnucleotides: A Sequence- and Spin Label-Flexible Strategy for EPR Spectroscopy in DNA
2016.J. Am. Chem. Soc.
Selective killing of cells triggered by their mRNA signature in the presence of smart nanoparticles
16857-16861, 2016.Nanoscale 8,
Electrophilic RNA for Peptidyl-RNA Synthesis and Site-Specific Cross-Linking with tRNA-Binding Enzymes
(43), 13553-13557, 2016.Angew. Chem. Int. Ed. 55
Graphene Oxide-Upconversion Nanoparticle Based Optical Sensors for Targeted Detection of mRNA Biomarkers Present in Alzheimer's Disease and Prostate Cancer
2016.ACS Sensors
Molecular Requirements of High-Fidelity Replication-Competent DNA Backbones for Orthogonal Chemical Ligation
2017.J. Am. Chem. Soc.
5-Formylcytosine does not change the global structure of DNA
2017.Nat. Struct. Mol. Biol.
RPA activates the XPF-ERCC1 endonuclease to initiate processing of DNA interstrand crosslinks


text:
Risk of Strokes Halts Sickle Cell Study
By Daniel Yee
Associated Press
The Washington Post
Monday, December 6, 2004; Page A02
ATLANTA, Dec. 5 -- A study aimed at determining whether some children with sickle cell anemia could be weaned off blood transfusion therapy has been halted because two young patients who stopped getting the procedure suffered strokes and others developed a high chance of strokes.
The National Institutes of Health decided to issue a clinical alert recommending that doctors continue with blood transfusions to reduce the risk of stroke among young sickle cell patients, even though the treatment has its own risk.
The study, called Stop II, was funded by the NIH's National Heart, Lung, and Blood Institute and involved 23 U.S. medical centers and two in Canada.
[ ... Read the full article ... ] (free registration required.)


text: Chris and I both got laid out this past week with a stomach flu that's been circling through camp. Fortunately, it's a pretty short-lived bug, and we're both feeling better now, but it's still kind of a bummer to be sick without the comforts of home. However, Chris went up to the safari lodge nearby to find me some ginger ale, just like my mom used to give me when I got sick as a kid. It was just what I needed, and I'm pretty sure that's what led to my rapid recovery!


text:
Scotties cheer way to competition
Nov 21, 2013 05:57AM ● Published by Community News Service
The Bordentown Regional High School cheer team. Back row: Liana Troiano, Alicia Saranin, Carlee Scott, Gina Capone, Lexie Berish, Alexa Santora, Jordan Pintinalli, Cierra Edwards, and Jessica Stanford. Front row: Emily LeMassena, Anngie Licarte, Katelyn Connelly, Caroline Tams, AJ Licarte, Steffi Agbulos, Breanna Anderson, Rebecca Gardner and Kiley Mabin. (Staff photo by Samantha Sciarrotta.)
By Samantha Sciarrotta
This year's Bordentown Regional High School varsity cheerleading team has been begging head coach Beth Bokop to take the squad to a competition for each of its last four seasons together.
The Scotties will get their first-ever chance Nov. 2 when they'll compete in Gotta Cheer's Turkey Tumble at Gloucester County College.
"They have wanted to for awhile," Bokop said. "This is the first year that I think they're ready. We have the talent. We have the dedication, the motivation. I think they're ready."
The girls said they wanted to compete to prove their capability not only to themselves, but to their peers, as well.
"It's kind of exciting going to a competition, because at the high school, we want to be known more as athletes," co-captain Jessica Stanford said. "Everyone will kind of see that we're up to that level."
Co-captain Cierra Edwards agreed.
"It's a different experience," she said. "It actually kind of brings us together because we want to win and do well."
Their last major test, their "dress rehearsal," came at the pep rally before the homecoming game on Oct. 18. It went off without a hitch.
"All of our schoolmates said we did well," Stanford said. "They really reassured us. It really raised our confidence."
Bokop said the sqaud will perform what is essentially the same routine, just with a few more technically difficult stunts and tumbles added into the mix. Assistant coach Maggie Anderson said competitions are similar to events like pep rallies in terms of the girls' mentality.
"I think they're excited and nervous all at once," she said. "It's kind of like what the pep rally was. They're so excited to actually go and do it and show off what they can do, but at the same time you're horrified and nervous that you're not going to do well or something's not going to stick."
Those nerves, though, fuel this team.
"We're all on our toes," Stanford said. "It's a little nerve-wracking. I think our team really runs on the pressure."
The competition will definitely provide that. Anderson said it will be much more high-octane than what the girls are used to at football games, but that can only add to their "excitement level and probably their performance."
"It's a little different because the crowd is actually a little more involved than at games or at the pep rally," she said. "They know when they're supposed to call and respond. Cheer parents know those things. There's a lot more energy than we're used to having."
Another difference? The scrutiny. Bokop said even the smallest error can result in a loss of points.
"It's different because there's so many little things that we need to be aware of," she said. "There's just a list of things that we can get deductions for, so they just have to be on the ball 100 percent the entire time. It's similar in the sense that we still need to have the crowd involved and the excitement and the energy, but it's different because at a game, no one's going to notice if one little thing happens, whereas there, everything's going to be picked out."
Some of the girls have competed before, but their only experience came either at the middle school or recreational levels. Bokop said the team isn't sure exactly how to approach its upcoming competition just yet, but the team members are anxious to get there.
"It's a whole different world, rather than just coming to games and cheering at games," Bokop said. "The competition world is totally different. I think it's something that they all wanted to experience. I think they're going to enjoy it. I think they're going to be nervous going in, but seeing how excited they were after the pep rally routine went so well, we're just keeping our fingers crossed that the same thing's going to happen then."


text:
Eliza and I dissuade Agnes S- from most immediate going visit Lady D-, for we confide that at present she lyes in exhaust'd sleep and that 'tis most needfull to her to do so. No, say we, she will be about recovering and 'twould be a deal better to go tomorrow, especial is Lord D- laid up with an attack of the megrim.
(I collect also that Lady P- is one that finds relish in talking of obstetrickal horrors both in cows and the human animal, and am not entire certain that she will mind on Agnes S-'s state and not talk of such matters while she is there.)
Miss S- is showing somewhat reluctant to hearken to our wisdom in this matter, when comes calling most extreme civil Mr H-, that wishes assure her that her sister is entire well but most exceeding tir'd, for you know, my dear, do you not, that 'tis quite justly known as labour? For I confide there are few tasks that make such demands upon the corporeal frame as bearing a child.
Miss S-, somewhat tearfull, thanks him very much for this kindness – 'tis indeed exceeding thoughtfull, especial in one that has, we daresay, been up all night himself attending upon the accouchement.
He adds, a fine large boy, that cries lustyly, an excellent sign.
Eliza walks with him to the door, having offer'd coffee that he has declin'd.
Sure, says I, for all his blunt ways, Mr H- is quite one of the kindest of men.
O, indeed, says Agnes S-, that then goes weep somewhat upon my shoulder.
My dear, says I, you have had a deal of turmoil these last few days, but I am like to suppose that what would do you a deal of good would be to undertake a little healthfull exercise by going riding with the children when His Lordship takes 'em to the Park.
She looks up and says, o, 'twould be very agreeable, does it not offer to look heartless.
I am ever confus'd, says I, that there are those that think because another suffers or is in some bad case, 'twill aid at all to go make themselves suffer quite needless. A little recreation is entire sanitive in your case, why, I am somewhat astonisht that Mr H- did not go advize it, must be because he is so tir'd himself.
After the riding-party go out, I go sit with my darling in the family room and she says that Mr H- convey'd to her some matter about the case that he was not sure was suitable to tell Miss S-: viz: that 'twas indeed a large infant and he was oblig'd to resort to forceps at the end –
Well, says I, at least he did not proceed to the Caesarean operation -
- that will leave certain signs on the child that should dissipate. And he confides that Lady D- took the business badly – for she is so very young – and he hopes that she will mind that 'twould be entire deleterious to go telling her sister the details of the ordeal.
I sigh. I wonder, says I, whether we might prevail upon her to stay a little longer, while her sister lyes in.
'Twould be an excellent thing – provid'd, says Eliza with a little grimace, that she does not go night-walking again – but she may consider that we tempt her with parties of pleasure away from her duty.
Why, says I, His Lordship's tiffin-party – a drawing-room meeting for the benefit of the T-s' work in New South Wales – 'tis hardly wild dissipation.
But, says my darling, she takes such a deal of enjoyment about everything – helping Josh in feeding his menagerie and keeping it clean, doing chymickal experiments with the girls and Miss N-, playing with the nursery-set. Sure she is a very agreeable guest.
She is an excellent young woman, says I.
Would that one might find her a husband of matching excellence, says my best wild girl, because does she not marry I fear she will be condemn'd to the life of a maiden aunt in her sister's household.
That is a very good thought, I reply, for altho' she could quite afford to live alone, or at least with some suitable companion, I think she would be reluctant to leave her sister for any other reason than that for which one forsakes all others. And I confide that Lord D- is entire happy that she lives with 'em –
I am like to think, says Eliza looking thoughtfull, that she must give a deal of assistance in household matters.
Most like! But the trouble is to find one that likes her for herself and not for her fortune or her family connexions. And one that she would believe was in all sincerity in his protestations, for she has a deal of suspicions about fellows that make suit to her, and one cannot consider it misguid'd.
We sigh.
There is a little tap upon the door and comes in Miss N-, that has had the day off so that she might attend Fraulein H-'s wedding.
We ask her how all went off, and she says, entire satisfactory, they are now man and wife, and Frau H- put up a very fine breakfast – very much, she adds, in a Germanick style or so she would confide – but they do not make any wedding journey, because she has classes to give, and he is to undertake correspondence for Mr K-'s enterprizes. She looks a little sadden'd by this.
'Twas all, she adds, a very quiet occasion.
I daresay she thinks a little mournfull of the still distant prospect of her own marriage to Mr L-.
I remark that sure 'twould be a deal more agreeable did one marry a husband that by his own merits and efforts had got himself into such a position that he might take one on some fine wedding trip. Does not need to be some Grand Tour - Martha S- will ever remark on how agreeable they found theirs to Weymouth.
Why, says Eliza, we had no wedding journey: or rather, we took a delay'd excursion to Scarborough after Harry was born. But at the time we wed 'twould have been exceeding imprudent for Mr F- to leave the works. (She most discreet says nothing of her own condition at the time, that would not have been favourable to travel.)
Miss N- says it must be a very fine thing to see the castles of the Rhine or the palaces of Venice, but 'tis surely who one sees 'em with that matters.
Entirely so! says Eliza.
Miss N- then says she purposes go and write up a few pieces for the paper, and Mr L- has had some thought that the little things she writes might be put up in a book.
An excellent thing, says I, sure there are those that do not aspire to be Miss Herschel and discover new comets, but would appreciate some little guide to what one may see in the night sky at particular seasons.
Miss N- smiles very pretty and takes her leave.
Eliza sighs and says, sure 'tis most exceeding selfish of her, but Miss N- answers so well that she cannot help hoping that Mr L- finds he may not go marry her for some years yet.
I laugh and say the world must be peopl'd!
Eliza laughs. The most Shakspearean of C-s will find somewhat in the Bard to any occasion!
We look at one another with exceeding affection.
Then comes a footman to say that the younger Mr K- has call'd, are we at home to him?
Indeed, says Eliza, show him in, and I will ring for tea.
Enters Sebastian K- and makes us a leg. Says he has some papers to leave about the pickle factory. could have left those with the footman, but came in to see whether Miss S- would like to join Vi and her other chicks at the theatre this e'en.
Why, says Eliza, she has gone ride in the Park with the children at present, but I confide she would be delight'd. Indeed answers exceeding well, for we are bidden, and so is Lady B-, to a dinner-party at the O- B-'s, and did not like to leave her alone here when she must still be fretting somewhat over her sister.
He asks have we had any news from P- House, and we recount to him the state of affairs.
He then says, he is most exceeding gratefull that we have put them in the way of acquiring a further German correspondence clerk, for indeed there is a deal more work in that line than they could expect Fraulein H- to manage. Have reacht an agreement with the fellow – sure he does not have the most gracious manner, but displays considerable apprehension, so mayhap there might be advancement for him in due course.
Is he not, he goes on with a slight frown, some connexion of Jacob S-?
No, says I, 'tis the U-s, that are associates of Mr S-'s father, the tenants of my little place in Surrey, that are some connexion. But I am like to think, I continue, that unlike the U-s, he does not adhere to ancestral ways, indeed, I would suppose him somewhat of a freethinker.
Sebastian K- then says, sure, he heard that the fellow went to church with Fraulein H- to be wed the day.
(I observe that he looks somewhat gratify'd by the thought, and I daresay has been in some concern that he might find the fair Fraulein in a stepmother's place.)
Eliza says, indeed, they have just heard all about it from Miss N-, that stood bridesmaid.
'Tis somewhat sudden, he comments, but I daresay Vi will be about giving 'em some present, for she is very fond of the Fraulein. Do you know whether she will still be going about giving lessons &C, or will she be devoting herself to keeping house?
As they continue reside with her mother, says I, that is consider'd an entire paragon of the domestick arts, I confide she will still be about her accustom'd round, tho' may come a time –
(That I daresay will be sooner rather than later.)
Of course, says Sebastian K-.
My dear naughty Eliza smiles and says the world must be peopl'd!


text:
New Band! Story Untold
Hopeless Records set the standard for incredible pop-punk bands. When they and Simple Plan members recommend a band, the band must be pretty good. Story Untold is Hopeless Records' newest signee, and their new single "History" was co-written with Simple Plan's Pierre Bouvier and Chuck Comeau.
New Band! Yellowcard
Everyone's favorite mid-2000s SoCal band is back! Yellowcard is reuniting with the Hopeless Records family, and it's a victory for the punk rock revolution.
New Band! Gideon
If hardcore is your scene, check out Equal Vision Records' newest band: Gideon. The Tuscaloosa, Alabama 5-piece has toured with bands such as Motionless In White, Memphis May Fire, and Being As An Ocean.
New Band! the Ready Set
Okay, The Ready Set is not necessarily new, but Jordan Witzigreuter has just signed with Hopeless Records and has some big things planned for 2016.
New Band! Flor
Fueled By Ramen (Panic! at the Disco, Vinyl Theatre, Against The Current) introduced a new band to its family today, Flor. Flor will be joining Halsey and Børns on the British leg of their tour.
New band! With Confidence
Today, Hopless Records (All Time Low, New Found Glory, The Wonder Years) signed a new band. I love learning about new bands. I need to constantly be listening for new music in order to spread my fangirling out to many bands instead of becoming deeply obsessed with one. So here's the lowdown on the new band:
June 2016


text:
Please note that the address for this place is approximate. Upon booking a stay, the rental owner will provide an exact address. Townhouse condominium in a fantastic location, a beautiful relaxing and very spacious home for you to enjoy. Over twenty VRBO 5-star ratings! Year-round accommodation with easy door-front parking. It is actually a large 3 bedroom, 3 bathroom, ... Dining Area, CD Player, DVD Player, Music Library, Satellite / Cable, Stereo, Television, Video Library, Broadband Access, Clothes Dryer, Fireplace, Heating, Internet, Iron & Board, Linens Provided, Living Room, Parking, Parking Off Street, Telephone, Towels Provided, Washing Machine, Wireless Internet, Wood Fireplace, Coffee Maker, Cooking Utensils, Dishes & Utensils, Dishwasher, Ice Maker, Kitchen, Microwave, Oven, Pantry Items, Refrigerator, Toaster, Balcony, Deck / Patio, Lawn / Garden, Outdoor Grill, Minimum Age Limit for Renters, non smoking only, not suitable for children, pets not allowed, Guests provide their own meals, condo, botanical garden, churches, cinemas, festivals, health/beauty spa, library, live theater, marina, museums, recreation center, restaurants, necessary, antiquing, bird watching, boating, miniature golf, outlet shopping, paddle boating, photography, scenic drives, shelling, shopping, sight seeing, walking, whale watching, wildlife viewing, Oceanfront, ATM/bank, fitness center, groceries, laundromat, massage therapist, medical services, basketball court, cycling, deepsea fishing, fishing, fly fishing, golf, hiking, kayaking, racquetball, sailing, snorkeling/diving, sound/bay fishing, swimming, tennis, wind-surfing
Beautiful Waterfront Home, roomy/convenient, on the edge of Boothbay Harbor cove
Boothbay Harbor, Maine 04538 USA
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text:
You Gotta Know
These ten topics are connected by only two things: There are five answers in each set and they all come up repeatedly in quiz bowl.
"The Waste Land" The five parts of T. S. Eliot's 1922 masterpiece "The Waste Land" are "The Burial of the Dead," "A Game of Chess," "The Fire Sermon," "Death By Water," and "What the Thunder Said."
Mitosis The five stages of the biological process of mitosis (the production of new body cells from existing ones) are interphase, prophase, metaphase, anaphase, and telophase. Interphase is not technically a part of mitosis, but it still sometimes finds its way in.
Nobel Prize Winners The five original winners of Nobel Prizes (1901) were Wilhelm Röntgen (physics, for the discovery of X rays), Jacobus Henricus van 't Hoff (chemistry, for laws of chemical dynamics and osmotic pressure), Emil Adolf von Behring (physiology or medicine, for his serum therapy remedy for diphtheria), Sully Prudhomme (literature, for his idealistic poetry), and Henri Dunant and Frédéric Passy (peace, for founding the International Red Cross and the first French peace society, respectively).
The Mighty Handful Five nationalist Russian composers are often referred to as "The Mighty Handful" or "The Five." They are Modest Mussorgsky (1839 -1881), Mily Balakirev (1837-1910), Alexander Borodin (1833-1887), Cesar Cui (1835-1918), and Nikolay Rimsky-Korsakov (1844-1908).
D-Day The codenames for the five beaches attacked in Operation Overlord on D-Day are Gold, Juno, Sword, Utah, and Omaha. The first three were attacked by British and Canadian forces while the latter two were assaulted by American troops.
Orders of Architecture There are five classical "orders of architecture," a term that primarily refers to the design of the columns used in the building. They are the Doric (simple, used for the Parthenon), Ionic (fancier, fluted with scrolls on their capitals), Corinthian (baroque, fluted with acanthus-like leaves for capitals), Tuscan (plain, similar to Doric), and Composite (mixture of Ionic and Corinthian). The latter two orders are Roman developments, the other three originated with the Greeks.
Cooperstown The first five members elected to the Baseball Hall of Fame were Ty Cobb, Babe Ruth, Honus Wagner, Christy Mathewson, and Walter Johnson.
Spectral Lines Hydrogen produces an infinite series of spectral lines. The first five of those series are named after scientists who observed them before it was known that they were actually examples of the same phenomenon. From lowest to highest energy of the final level, they are known as the Lyman, Balmer, Paschen, Brackett, and Pfund series. Only the Balmer series exists in the visible spectrum.
Platonic Solids There are only five regular polyhedra, three-dimensional shapes with congruent regular polygons for sides. These, known as the Platonic solids, are the tetrahedron (4 triangular sides), cube (6 square sides), octahedron (8 triangular sides), dodecahedron (12 pentagonal sides), and icosahedron (20 triangular sides).
Pillars of Islam Islam has five fundamental tenets of religious life, a group known as the Pillars of Islam. They are the declaration of faith (Shahadah), prayer (Salat), giving charity to those in need (Zakat), fasting during the month of Ramadan (Sawm), and the pilgrimage to Mecca (Hajj) to be performed once in each adherent's lifetime.


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Nobel Prize winner Malala Yousafzai receives offer to study at UK university
By PRIYA JOSHI
Malala Yousafzai has received an offer to study at a British university. The 19-year-old, who is the youngest person to be awarded the Nobel Peace Prize, shared the news while speaking at an education conference in Birmingham.
Addressing the auditorium she revealed she had received an offer to study Politics, Philosophy and Economics (PPE), conditional on achieving three As in her A-Levels.
While she did not reveal the name of the university, according to Mail Online she has previously revealed that she applied to Lady Margaret Hall, Oxford, in the hope of following in the footsteps of her hero, former Pakistani president Benazir Bhutto, who studied there.
Giving the final speech at the Association of School and College Leaders (ASCL) conference, she said: "I'm studying right now. I'm in year 13, I have my A-Level exams coming and I have received a conditional offer which is three As.
"So I need to get the three As, that's what my focus is right now, and I hope to continue my work and also continue my studies.
"And I'm really thankful to you all for you support for encouraging me for my mission.
"That's what makes me and keeps me so strong so thank you so much for that," she added.
She explained that along with her degree, she will continue to work for the Malala Fund. "My goal is to make sure every child, girl and boy, get the opportunity to go to school," she said.
"It is their basic human right. I will never stop until I see the last child going to school."
The education campaigner received a standing ovation for her rousing speech at Birmingham's International Convention Centre.
An ardent child campaigner for the rights of oppressed children in the Swat valley in her native Pakistan, Yousafzai was shot in the head after her school bus was ambushed by the Taliban in 2012.


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Florists Blenheim, ON
5 results for Florists in Blenheim, ON
- Lasting Memories Flowers & Gifts Ontario, 101 Ellen StreetN0P 1A0 Blenheim, ON (519) 676-0530Closed
Order flowers from Lasting Memories Flowers, your choice for local Same Day flower delivery in the Blenheim, ON area. Order online 24 hours a day. ... Balloons, Florists, Basket, Supplies, Wedding Planning, Service, Gift Baskets, Florist Retail
- Dawson Flowers Ontario, Talbot StreetN0P 1A0 Blenheim, ON (519) 676-8192Closed
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- Dawsons Flowers and Gifts Ontario, 71 TALBOT WN0P 1A0 Blenheim, ON (519) 676-8191Closed
Save money and time with Sameday Delivery. Order flowers safely and securely online from Dawson's Flowers & Gifts. Our Arrangements are artfully designed with fresh flowers and hand delivered right to ... Magasinage et Magasins de spécialité, Florists, products and services, Florist Retail, parcels, s...
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Order flowers from Pizazz! Florals & Balloons, your choice for local Same Day flower delivery in the Chatham, ON area. Order online 24 hours a day. ... Florist Retail, Fleuristes, Gift Baskets, Florists, parcels, Fleuristes & magasins de fleurs,...
- Lakeview Greenhouses and Farm Ltd Ontario, 8381 Hwy, Rr#1N0P 1A0 Blenheim, ON (519) 676-7110
In operation since 2002 Lakeviews 7.5 acre modern greenhouse complex is equipped with some of the most technologically advanced systems in the world. With state of the art climate contol, watering,...
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- Ross Nursery & Garden Centre Ontario, 335 Indian Creek Rd. EastN7M 5J6 Chatham, ON (519) 352-7840Closed
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- A Touch Of Green Ontario, 33 MAIN EN0P 2C0 Ridgetown, ON (519) 674-5132Closed
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- Ross Flowers ON, 869 CHARING CROSS ROADN7M 5H3 Chatham, ON (519) 352-7840
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- Purple Pansy The ON, 46 WILLIAM STREET SOUTHN7M 4S3 Chatham, ON (519) 354-5555Closed
The Purple Pansy flower boutique, located in downtown Chatham. ... Wedding flowers, Floral arrangements-Kent, Florists, bridal supplies, Fleuristes, Florist-Kent,...
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removing /usr/local/lib/libSDL2-2.0.so.0 solve the issue
Search Criteria
Package Details: vkquake-git 0.95.r2.g182167f-1
|Git Clone URL:
|https://aur.archlinux.org/vkquake-git.git (read-only)
|Package Base:
|A modern Quake 1 engine. Forked from Fitzquake. This version contains Vulkan API support (git-latest).
|Upstream URL:
|game port quake quake1 quakespasm vkquake
|Last Packager:
|First Submitted:
|2016-08-14 02:22
|Last Updated:
|2017-03-25 13:11
Dependencies (13)
- flac (flac-git)
- git (git-git)
- glibc (glibc-wsl)
- libgl (amdgpu-pro-libgl, catalyst-firepro, catalyst-libgl, catalyst-test, catalyst-total, catalyst-total-hd234k, catalyst-total-pxp, glshim-git, libglvnd-git, libhybris-ext-libgl-git, libhybris-libgl-git, mesa-hybris-libgl, mesa-libgl-noglvnd, nvidia-346xx-libgl, nvidia-libgl-352, nvidia-libgl-beta, nvidia-libgl-full-beta, nvidia-libgl-full-beta-all, nvidia-libgl-llb, nvidia-libgl-vulkan-developer-beta, nvidia-tesla-libgl, libglvnd, nvidia-304xx-utils, nvidia-340xx-utils)
- libmad
- libmikmod
- libogg (libogg-git)
- libvorbis (libvorbis-aotuv, libvorbis-aotuv-lancer, libvorbis-git)
- libx11 (libx11-nokeyboardgrab)
- opusfile (opusfile-git)
- sdl2 (sdl2-hg, sdl2-ime-support, sdl2-mir, sdl2-rbp-bin)
- tslib (tslib-git)
- vulkan-validation-layers
Required by (0)
Sources (3)
Latest Comments
edoantonioco commented on 2017-01-28 13:48
edoantonioco commented on 2017-01-27 17:29
but I cant symlink since vkquake doesnt have any libts-1.0.so.0 library. Reinstalling the game doesnt change anything
ProfessorKaos64 commented on 2017-01-22 21:24
This was a similar issue like those of ut2004 and is likely due to the latest tslib:
Latest update of tslib broke this game for me. In case if someone got problem launching it because of missing libts, try this command from root:
# ln -s /usr/lib/libts-1.2.so.0 /opt/ut2004/System/libts-1.0.so.0
Arch is shipping libts-1.3.so.0 now, so rebuild the package or symlink it. See: https://www.archlinux.org/packages/extra/x86_64/tslib/
edoantonioco commented on 2017-01-21 16:35
Its not working on Manjaro, same goes for both vkquakes on AUR
"vkquake: error while loading shared libraries: libts-1.2.so.0: cannot open shared object file: No such file or directory"
ProfessorKaos64 commented on 2016-09-13 08:01
file /usr/bin/vkquake
/usr/bin/vkquake: ELF 64-bit LSB executable, x86-64, version 1 (SYSV), dynamically linked, interpreter /lib64/ld-linux-x86-64.so.2, for GNU/Linux 2.6.32, BuildID[sha1]=60ca056c93cf1f9e707a9f5867cd3322d239d513, stripped
The desktop file points to this. I just tested this on a new rev. I kind of woke up to eat a midnight snack, so i'll check soon tomorrow :) It's a git package, not meant to actually* be named vkquake-git, in same vein that retroarch-git provides /usr/bin/retroarch, not /usr/bin/retroarch-git instead. Same goes for the desktop files.
Vash63 commented on 2016-09-13 07:43
/usr/bin/vkquake-git is now 644, needs to be 755, and the desktop file is improperly named 'vkquake' instead of 'vkquake-git' and points to /usr/bin/vkquake not /usr/bin/vkquake-git.
ProfessorKaos64 commented on 2016-09-13 07:42
.. "Provides: vkquake", not "vkquake-git". This recently changed to reflect the proper executable.
edoantonioco commented on 2016-09-13 05:46
~]$ vkquake-git
bash: /usr/bin/vkquake-git: Permiso denegado
~]$ sudo vkquake-git
sudo: vkquake-git: command not found
ProfessorKaos64 commented on 2016-09-12 14:20
@Vash63, ok check now please.
Vash63 commented on 2016-09-12 07:10
The PNG file in the tarball is HTML. Also the .desktop entry references /usr/games/vkquake but the PKGBUILD installs the binary to /usr/bin/vkquake-git.


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Last year we had the pleasure of being invited to style the guests at Highclere Castle's Vintage Garden Party, they have just launched tickets for this years event. This year the theme is the Roaring 20's
If you are thinking of going please enjoy reading below, hopefully this will set the scene for you.
Vintage Victory Rollers had the privilege of styling at the Vintage Garden Party at Highclere castle, even though I myself am not a viewer of Downton Abbey, I didn't need to be. From the minute my team arrived I felt part of this period drama.
Nothing could have prepare us for just how grand Highclere Castle was, as we drove into the ground's along a very picturesque drive the castle appeared. It was jaw dropping. Due to the English weather our pop salon was moved into the castle, we were where I can only describe as the 'Downstairs'
Our team got straight to it transforming one of the teaching rooms into our salon for the weekend. During set up The Countess od Carnarvon arrived, she had roller set her hair for the day but it was destroyed due to the rain. She had a beautiful hat so I dressed her hair to compliment this. Lady Carnarvon was a truly lovely lady, ever so friendly and kept ensuring we were happy and had everything we needed.
10am the castle opened to the public. The weather did not dampen anyone's spirits. Visitors took their tour around the castle and the Egyptian exhibition and we were positioned so that the salon would be the last stop. I couldn't believe just how many people came dressed up; some of the costumes were hired, some were handmade and some were lucky enough to have true vintage. They all looked fabulous. Even the gents got into character. I was unaware of the huge following Downton Abbey has in the states – people from Utah , Texas , Denver and San Francisco had come over here just for this prestigious event. Every lady that sat in the styling seat had a different story to tell and we have now made connections across the globe.
A few of the highlights that stick out in my mind are twins from the States, both very glamourous and wanted hat hair, only one of the twins had it done at first then the other insisted when she saw how lovely it looked. Some of the ladies had seen we were attending on the programme and were happy to come in and have a pamper. We met a lady from Denver who was writing a book about the art of drinking tea and her book focused on Tea on the Titanic and at Highclere Castle, whilst she was sat in the chair being styled Lady Carnarvon reappeared, she wanted to have her hair done for an evening soiree. The ladies that were in the salon at this point were overwhelmed that she was there. She was so graceful and happy to have photos taken. Since the event we have be contacted by a number of the ladies we styled to thank us for making them feel amazing!
During the weekend they had Morris dancers on the lawns and a string quartet performing in the music canopy. The lunches that were provided were in beautiful individual boxes containing a Highclere sandwich, traditional pork pie, homemade cupcake and a bottle of water. It wasn't until the Sunday that we got to really soak up some of the atmosphere – we walked the grounds with the sun beaming on the castle, the sounds from the carousel in the background, people walking around in period drama costumes, the grand piano being played in the outside art deco cocktail bar. You really did then start to feel like you were at Downton. Each day they had a prize giving which was hosted by the Earl and Countess of Carnarvon, they awarded the best Upstairs & Downstairs, the best Carson, and the best hat. A number of the ladies that we had styled were entered into this competition.
I can't express in words just how amazing the experience was, on Saturday we took the opportunity to walk around the castle. In the rooms that were featured in Downton Abbey that had photographs with scenes from the TV series. Just walking around the castle and soaking it all up made me feel very proud to have been part of this event. We have been asked back next year for their garden party and taking bookings from the states already!
If you would like to book in for 20's inspired hair & make up please contact us!


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5 of
80 results
A moreish blend of chickpeas, squash and sweet potato, flavoured with cumin and turmeric.
A comforting Italian classic, packed with roasted courgette and asparagus and seasoned with basil.
Determined to be a slim bride, Ashleigh gained so much more than a size-10 figure…
Warm up a chilly autumn night with a slice of hot-...


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My Content
Membership has its privileges! Sign up or sign in to gain full access to both All About Jazz and Jazz Near You. Learn more.
Track Listing: Angel Of Death; Piece By Piece; Necrophobic; Altar Of Sacrifice; Jesus Saves; Criminally Insane; Reborn; Epidemic; Postmortem; Raining Blood.
Personnel: Erik Hinds: h
Title: Reign in Blood | Year Released: 2005 | Record Label: Solponticello
Develop a column, write album reviews, cover live shows, or conduct interviews.


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Highlands Park,
Ben Lomond, CA
From The Page (May, 2005):
We invite you to join the poachers and rascals of the canton as we celebrate our latest "acquisitions." This year the Lord and Lady Anderson have graciously given us sanctuary on their lands. We will laugh and celebrate and choose our new Lord and Lady of Misrule. Feasting will include portions of what our poachers can bring. This is a family event; we welcome the younger of our ruffians to accompany their parents. We even have our own playground for them to frolic in. The site borders the San Lorenzo River, so the water-safe ones can splash and wade as well.
Site Information: The site opens at 10 am and closes at 6 pm. The site fee is $10 for members eating the poacher's meat and $13 for non-members, $7 for members not eating meat and $10 for non members. We are providing meat (venison, beef and chicken) but we ask that you bring dishes to share based on your SCA first name: A-H Breads/ Cheeses; I-P Salads/Vegetables; Q-Z Pastries/Puddings/Sweets. Period dishes are always appreciated. Bring your own beverages. This is a dry site. Highlands Park has plenty of parking, but there is another event happening this day. Please car pool. Off-site parking and shuttle service are available if you make arrangements in advance with the autocrat, (website address omitted).
Autocrat: Robert of Ravenshill (contact info omitted).
See photos of this event
Description of this event (if any), taken from The Page, or from memory of at least one person who attended the event.
The West Kingdom History Website was created by and is maintained by Hirsch von Henford (mka Ken Mayer).


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ChanelDark Purple, Black, and Silver Chanel Patent Leather Metal Cap Toe Pumps
These pumps divert from the typically classic Chanel look with sleek leather, edgy accents, and an unexpected hue. For the modern girl with an envious shoe collection who prefers a muted palette. Constructed of dark purple patent leather with an almond shaped, black patent leather cap toe. High, chunky heel with hidden platform for comfort. Silver toned metal 'CHANEL' bar at toe front. Comes with dust bag. Size: 38
Made in: Italy Color: Dark Purple, Black, Silver Fabric Content: Leather Condition: Pre-owned. This item is in good condition. Faint scratches. No other visible signs of wear and tear.
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I've written a lot of blog posts about writer's block and rejection and many of the other things that plague most writers, including fear. This past week I've been absolutely crippled by fear and I am writing this blog post in hopes that writing it will force me to follow my own advice and get over this fear.
The first thing that I have learned about writing and fear is that, for me, fear of success is actually far more powerful than fear of failure. When people ask me what's getting in my way, I can't say writer's block because, as I've written before, writer's block is a myth.
I was writing along at a fairly rapid pace. Then, a group of agents told me that they liked what they read and that my story actually had some potential. This news actually crippled me for a couple weeks. I was so scared of failing to live up to the expectations of the agents that I let that get in the way of my writing.
Now, I'm over 70% of the way through one pass through my manuscript (I work on it in sweeps, editing in large chunks to preserve continuity). Every morning I wake up and my first thought is: I hate my story. My second thought is: the story isn't tight enough. And my third thought is: It's not worth finishing this story because nobody will ever read or enjoy it.
This last thought is the death knell for a writer and I realize this and have to force myself to suppress that thought every time I sit down to write.
The subconscious mind plays tricks on your conscious mind. It plays these tricks when you are trying to get over an addiction, convincing you that you cannot function without the object of your desire (my preciousssssss!). It tells you that you should give up now because it is actually trying to spare you the pain you might feel if you spend another 8 months on this book and it fails.
The trick is to ignore the little voice in your head. Lately, I've been giving this voice too much power, too much power to prevent me from writing and to prevent me from doing the thing I enjoy doing most – creating stories.
So, if you happen to be one of the two people who actually read this blog, take heart. You have the ability to tell that voice to screw off and that you're going to finish your book because it needs finishing, not because you think it'll get published or because you think it'll be a bestseller or even because you think one person might read it.
You'll finish your book because you have a story that needs an ending and that's that.
Now to follow my own advice. I'll post sometime next week to let you know how much I have gotten over the feeling that my story is terrible, and we'll see how much closer to the ending I have come.


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DWP seeks £130k tech chief to lead digital service delivery
Department recruiting for senior digital professional to oversee development and design teams
Photo: PA
The Department for Work and Pensions is offering a six-figure salary as it seeks a technology leader to oversee the creation of a new computing infrastructure and the delivery of its digital services.
The DWP is recruiting for a digital delivery director, a role which will pay about £130,000 per year. The department said that "this is a critical, hands-on leadership role, with responsibility for next-generation enterprise-wide architecture design, and infrastructure on which millions of users, and hundreds of products, rely".
The responsibilities that come with the post include designing and implementing the use of both public and private cloud technology across the department, as well as leading digital service delivery, with a focus on security and minimising downtime. The digital delivery director will also head up architecture design and software development teams.
- Labour MPs slammed for attacking DWP officials over bonus payments
- DWP creates new DG role for Universal Credit
- Most DWP job losses 'will be back office staff'
In the candidate information pack, DWP chief information and data officer Mayank Prakash said: "There's never been a better time to join DWP Digital, if you're inspired by the opportunity to reimagine our country's future using data, design, and technology. DWP offers genuinely challenging and fulfilling career opportunities for leaders interested in making a genuine difference to society on a massive scale."
The digital delivery director job will be based, variously, in London, Manchester, and Newcastle. Candidates have until 18 September to apply, with a meeting being held on 3 October to define a shortlist. Assessments of shortlisted applicants will be held on 16 October, with panel interviews scheduled for 10 November.
It is the second high-level technology post that the DWP has advertised in the space of a few weeks; last month the department announced that it is offering a salary of up to £140,000 a year for a new chief technology officer.
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