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PhenX has collaborated with the National Center for Biotechnology Information (NCBI) database of Genotypes and Phenotypes (dbGaP) to use PhenX measures to identify dbGaP studies for cross-study analysis. For new study submissions to dbGaP, PhenX provides a Data Dictionary compatible with the dbGaP data submission packet, where the "Variable Source" is pre-filled with "PhenX." For existing studies in dbGaP, PhenX is linking dbGaP studies by mapping PhenX variables to dbGaP variables as "comparable" or "related."
PhenX-dbGaP variable mapping results can be accessed in both PhenX and dbGaP. In the PhenX Toolkit, these mappings can be found in the "Variable" section in the protocol page, or via "dbGaP Variable Mapping" under the "Search" menu. In dbGaP, the mappings can be found in "dbGaP Advanced Search" (faceted browsing) under "Common Data Elements" in the "Variable" tab. Additionally, the mappings can be found in dbGaP in the "Search" box by selecting the "PhenX" field. This development enables both PhenX and dbGaP users to identify potential dbGaP studies for cross-study analysis
The PhenX Toolkit released two Early Psychosis specialty collections in the PhenX Measures for Mental Health Research (MHR) Collection, funded by the National Institute of Mental Health (NIMH). Dr. Gregory K. Farber, director of the Office of Technology Development and Coordination at NIMH, is the project scientist. Led by Drs. Lisa Dixon and Dost Öngür, co-chairs, the Early Psychosis Working Group (WG) selected 26 new measures, which were approved by the PhenX Steering Committee.
The Early Psychosis Clinical Services Specialty Collection presents 19 standardized measures of diagnosis, symptoms, functioning, treatment interventions, and recovery outcomes. The Early Psychosis Translational Research Specialty Collection presents eight specific approaches for anatomical imaging and cognitive assessment. Two measures (Family History of Mental Illness and Premorbid Adjustment and Psychosis) are included in both specialty collections.
On January 25, 2017, NIMH posted a "Notice Announcing the Availability of Common Data Elements for Research Related to Early Psychosis," strongly encouraging NIMH grantees and applicants to incorporate the measures into research protocols. "By encouraging the use of this set of data elements," the notice states, "NIMH is trying to promote these into the category of common data elements widely used by a research field."
The MHR Collection also includes specialty collections for Suicide, Post-traumatic Stress Psychopathology (including PTSD), and Eating Disorders and a core collection of PhenX measures recommended for use by all mental health researchers. For more information about the project's implications for investigators in the mental health research community, see NIMH's Notice Announcing Data Harmonization for NIMH Human Subject Research via the PhenX Toolkit.
The Pregnancy Working Group (WG), chaired by Dr. Siobhan Dolan of Albert Einstein College of Medicine, recommended a set of Pregnancy measures for inclusion in the PhenX Toolkit. These measures were reviewed and approved by the PhenX Steering Committee and released in the Toolkit on January 31, 2017. The Pregnancy Domain has 14 measures and 1 protocol in Supplemental Information. At the WG's suggestion, the domain page has a link to "Additional Relevant Measures," providing access to the large number of pregnancy-related measures already in the Toolkit. A poster highlighting the Pregnancy measures was presented at the National Institute of Environmental Health Sciences (NIEHS) Environmental Health Sciences Fest in December 2016 in Raleigh, NC (see "PhenX on the Move" below).
Changes to the Reproductive Health domain in the PhenX Toolkit were released on April 11, 2017, culminating a thorough review by the Reproductive Health Expert Review Panel (ERP), led by Dr. Andrea Dunaif of Northwestern University.
The ERP reviewed 15 measures in the Reproductive Health domain and two measures in Supplemental Information. All ERP recommendations were approved by the Steering Committee at its February 2017 in-person meeting.
In the PhenX Toolkit, the "Process and Review" section of each protocol provides a summary of any ERP changes. Protocols that have been updated, replaced, or retired are available on the Archived Measures and Protocols page.
PhenX protocols will be available soon in Form Builder at the cancer Data Standards Registry and Repository (caDSR), providing the ability for Web-based data collection. You can search and download PhenX protocols and incorporate them into your data collection protocols.
caDSR is a metadata registry in the form of data elements, forms, models, and components of these items maintained and administered by the National Cancer Institute (NCI). Form Builder at caDSR is a registry of data collection forms for cancer studies and other types of studies. This development extends the availability of PhenX protocol to the cancer research field and establishes a base for standardizing the questions on the PhenX measures.
The PhenX Steering Committee (SC) met in person in Chevy Chase, MD. The SC heard speakers from the database of Genotypes and Phenotypes (dbGaP), the National Institutes of Health (NIH) Sexual and Gender Minority Research Office (SGMRO), and the Clinical Genome Resource (ClinGen).
The SC received updates on the Pregnancy and Geriatric Working Groups and from three Expert Review Panels (ERPs) reviewing Respiratory, Neurology/Psychosocial/Psychiatric, and Reproductive Health measures in the Toolkit. The SC approved the ERP's recommendations for the Reproductive Health domain. Representatives of the Mental Health Research and Tobacco Regulatory Research administrative supplements presented updates and items for discussion.
The PhenX Team presented information on recent conferences, presentations and publications in process. The SC discussed potential new collaborations and new Toolkit content moving forward.
Resources like the PhenX Toolkit are increasingly important in data archiving for environmental health sciences research, according to two panelists at the National Institute of Environmental Health Sciences (NIEHS) 50th anniversary Environmental Health Sciences FEST in Durham, NC, December 5-8, 2016. Dr. Fred Wright, Director of the Bioinformatics Program at North Carolina State University, and fellow panelist Dr. Susan Pinney, Deputy Director of the University of Cincinnati's Center for Environmental Genetics, commented on the PhenX Toolkit in a panel discussion December 6 titled "Perspectives on Data across the Research Lifecycle." Mike Phillips provided more details on the Toolkit on December 7 with a poster presentation, "The PhenX Toolkit: Standard Phenotype and eXposure Measures for Pregnancy Research."
Dr. Helen Pan gave a webinar, "Linking Data in dbGaP Using PhenX Measures," to the Clinical Common Data Elements Task Force (CDETF) for the National Library of Medicine (NLM), National Institutes of Health (NIH) March 28, 2017.
Dr. Helen Pan gave a podium presentation, "Linking Data in dbGaP Using PhenX Measures," at the American Medical Informatics Association's 2017 Joint Summits on Translational Science in San Francisco, CA, March 27, 2017.
Mike Phillips presented a poster, "The PhenX Toolkit: A Resource for Standard Phenotype and eXposure Measures for Pregnancy and Environmental research," at the Society of Toxicology's 56th Annual Meeting and ToxExpo on March 13, 2017, in Baltimore, MD.
PhenX Tobacco Regulatory Research Project Scientist Dr. Kay Wanke presented a poster, "Tobacco Regulatory Research Measures in the PhenX Toolkit," at the Society for Research on Nicotine & Tobacco Annual Meeting on March 10, 2017, in Florence, Italy.
Drs. Carol M. Hamilton and Helen Pan gave a webinar, "The PhenX Toolkit: Standard Measures for Collaborative Research," to the TOPMed Phenotype Harmonization Committee on March 2, 2017.
Drs. Carol M. Hamilton and Helen Pan gave a webinar for the Clinical and Translational Science Awards (CTSA) Informatics Domain Task Force meeting on February 3, 2017.
Dr. Hamilton gave a webinar to the Clinical Common Data Elements Task Force (CDETF) for the National Library of Medicine (NLM), National Institutes of Health (NIH) on November 4, 2016.
Dr. Dixon is a Professor of Psychiatry at the Columbia University Medical Center, where she directs the Division of Behavioral Health Services and Policy Research and the Center for Practice Innovations (CPI) at the New York State Psychiatric Institute. Dr. Dixon is an internationally recognized health services researcher with more than 25 years of continuous research funding from the National Institute of Mental Health, the U.S. Department of Veterans Affairs, and foundations. As the director of CPI, she oversees activities for the New York State Office of Mental Health in implementing evidence-based practices in behavioral health programs throughout the state. She leads OnTrackNY, a statewide initiative designed to improve outcomes and reduce disability for individuals experiencing their first episode of psychosis. Dr. Dixon's grants have focused on improving the quality of care for individuals with serious mental disorders, with emphasis on services that include families, reducing the negative impact of co-occurring addictions and medical problems, and improving treatment engagement and adherence. Dr. Dixon's work has joined individuals engaged in self-help and outpatient psychiatric care, as well as clinicians and policy makers, in collaborative research endeavors. Dr. Dixon assumed the role of editor-in-chief of the journal Psychiatric Services in January 2017. She has published more than 250 articles in peer-reviewed journals and has received many awards, including the 2009 American Psychiatric Association Health Services Senior Scholar Award and the Wayne Fenton Award for Exceptional Clinical Care.
Dr. Öngür obtained his MD/PhD degree in 2000 from Washington University in St. Louis and completed his psychiatric residency training at the MGH/McLean Adult Psychiatry program. He is the chief of the Psychotic Disorders Division, responsible for all clinical services serving patients with psychotic disorders, including a first-episode psychosis subspecialty program. In addition to his clinical work, he receives funding from the National Institute of Mental Health for clinical and brain imaging research in patients with schizophrenia and bipolar disorder. He is an associate professor of psychiatry at Harvard Medical School and the author of more than 130 articles on research into the neurobiology of bipolar disorder and schizophrenia. He has won awards from the Harvard Medical School for his teaching and mentoring, and he is the associate editor of JAMA Psychiatry.
Dr. Dolan is professor and vice chair for research in the Department of Obstetrics and Gynecology (Ob/Gyn) and Women's Health at Albert Einstein College of Medicine and Montefiore Medical Center. A graduate of Brown University and Harvard Medical School, she trained in Ob/Gyn at Yale New Haven Hospital and then completed a fellowship in clinical genetics at Albert Einstein College of Medicine and a master's degree in public health at Columbia University.
In addition to her clinical work in the Division of Reproductive and Medical Genetics, Dr. Dolan is involved in research on the genetics and epidemiology of preterm birth, as well as the use of group prenatal care to prevent preterm birth. In addition to her clinical work, she serves as a medical advisor to the March of Dimes.
Dr. Dunaif is the Charles F. Kettering Professor of Endocrinology and Metabolism at the Feinberg School of Medicine, Northwestern University. She is the director of the National Institutes of Health-supported Northwestern University Specialized Center of Research on Sex Differences. Formerly, she was chief of the Division of Endocrinology, Metabolism and Molecular Medicine at the Feinberg School of Medicine for 10 years. Before joining Northwestern in 2001, Dr. Dunaif held faculty appointments at the Mount Sinai School of Medicine, Pennsylvania State University College of Medicine, and Harvard Medical School. Dr. Dunaif is an internationally recognized expert in endocrinology and women's health. Her research on polycystic ovary syndrome (PCOS) has shown that it is a leading risk factor for type 2 diabetes mellitus. Further, this research has revolutionized the treatment of PCOS with insulin-sensitizing drugs.
Most recently, Dr. Dunaif led an international team that successfully mapped novel susceptibility genes for PCOS. Dr. Dunaif has more than 135 original scientific publications and has edited four books. She has received numerous awards and honors including the Endocrine Society's highest award for clinical research, the Clinical Investigator Award, and a Doctor Honoris Causa from the University of Athens Medical School. She has been elected to the American Society for Clinical Investigation and the Association of American Physicians. She is a past president of the Endocrine Society, a former associate editor of the Journal of Clinical Endocrinology and Metabolism and Obesity, and a past chair of the National Institutes of Health Integrative and Clinical Endocrinology and Reproduction Study Section.
Previous PhenX Newsletters
Phenx Steering Committee


text: Bear seasons 'spread the wealth around' By John McCoy January 21, 2012 Story Share One thing can be said about West Virginia's bear-hunting seasons: Year to year, they change quite a bit.In 2009, hunters killed more bears during the bow season than they did during the December gun season. In 2010, hunters killed many more bears during the December gun season than they did during the bow season.Last year, the archery season and December gun seasons balanced out, but hunters killed a lot more bears during the September gun season.Chris Ryan, the Division of Natural Resources' game management services supervisor, has a simple explanation for the differences.Mast.Ryan said acorns and other mast items were exceptionally scarce in 2009, and bears were concentrated in areas where food was relatively abundant. Bowhunters took advantage, but gun hunters couldn't because hungry bears went into hibernation before the December season could really get started.In 2010, a record-breaking mast crop scattered bears to the four winds and made them difficult for bowhunters to find. The abundance of food kept bears out of their dens until late in the gun season, and gun hunters took advantage.Last year, when the mast crop was pretty average, bowhunters killed 619 bruins, December gun hunters killed 681 and September gun hunters killed 631.Ryan considers the September statistic particularly significant. "In terms of keeping the bear population in check, the September season was very important," he said.DNR officials hold the September season in areas where bear populations have risen well above the agency's management guidelines. If hunters hadn't killed that many bears during the September season, many would have survived the bow and December gun seasons - and that, in turn, would have allowed bear numbers in those areas to increase even more.Ryan believes hunters have grown more accepting of the September season, partly because it presents additional opportunity and partly because it represents a relatively gentle approach toward reducing the number of bruins."Hunters are aware of the steps in our [bear-management] plan," he explained. "If a county's population comes in above our goals, we implement a September season. If the population continues to grow, we implement a bear season that runs concurrent with the [firearm] buck season. If it continues to grow above that, we raise the bag limit."Hunters know we have to keep the number of females in check. They've taken [the September season] to heart and are getting out there."Last fall's September hunt lasted six days in 11 counties and just three days in nine more. Ryan said the relatively high kill during a relatively short season in relatively few counties is a testament to bear hunters' willingness to help manage the population. "We're very happy with the cooperation we got from hunters," he added. "We rely on hunters to take part in our seasons so we can bring the population down gradually and avoid dramatic drops. The numbers have come down gradually, so it has worked."Another benefit to last year's bear seasons is that they "spread the wealth around" in a way never before experienced."Everyone got a piece of the pie during this past season," Ryan said. "Gun hunters took advantage of the September season, bowhunters took advantage of the bow season, and buck hunters got their share during the buck season. We're very pleased with the results." Story Share Story Share Trending Now 1 Philanthropist Betty Schoenbaum of Shoney's fortune turns 100 2 YWCA Charleston's Women of Achievement to be honored in March 3 WVU pulls away from Kansas for 56-34 win 4 Deer in 8 WV counties found dead from EHD 5 'Heroin(e)' spotlights women helping combat Huntington's drug crisis Outdoors notes -- Jan. 22 Previous Story From the �small world' file Next Story

subset: commoncrawl


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PORTER RANCH, LOS ANGELES (KABC) --Congressman Brad Sherman toured the site of an ongoing gas leak near Porter Ranch on Tuesday, questioning whether things will ever be safe for the community.
Sherman, along with state and city lawmakers, visited the site of the leaking well after the Southern California Gas Company set a timetable to hopefully cap the leak by late February.
The plan was to send fluids, cement and mud through a relief well to clog the damaged well.
After looking closely at the relief well, Sherman was not convinced it will work and construction of a backup well was behind schedule.
"You are trying to hit a pipe from drilling down a mile and a half - that's not an easy thing to do. Success is not guaranteed. There's no guarantee that relief well one will be successful, and relief well two is behind the schedule that I would have liked to have seen," Sherman said.
Thousands of residents have already left their homes and many were also not optimistic.
"I'm not convinced they are going to cap it next month or they wouldn't be building that second relief well," said Lin McDonough, a Porter Ranch resident. "If they were a 100 percent sure they could catch it with the first relief, well then they wouldn't need the second well."
Lawmakers said as the leaking gas continues to travel miles beyond the Porter Ranch area, SoCal Gas has expanded its outreach to help residents within a 5-mile radius of the damaged well.
Sherman said most residents in Granada Hills and Chatsworth, all of Porter Ranch and a large chunk of Northridge can get help that consists of relocation or putting carbon filters on heating and cooling systems.
Meantime, the South Coast Air Quality Management District will hold a hearing on Wednesday to address residents' concerns. Residents will be shuttled by bus from a site in Northridge to the SCAQMD headquarters in Diamond bar for the 9 a.m. meeting. The hearing can be viewed on the SCAQMD website, www.aqmd.gov/home/library/live-webcast.
Also, the Los Angeles County Health Department will hold a separate meeting at 10 a.m. to address its response to the gas leak.


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City Living Showcase at Melbourne Grand
Experience the very best in city living and explore Melbourne Grand's city homes at its FREE open inspection. Open from Thursday, September 21 – Sunday, September 24.
Experience the very best in city living and explore Melbourne Grand's city homes at its FREE open inspection. Open from Thursday, September 21 – Sunday, September 24.
Knowing who you are and what you're all about will lead to more fulfilling relationships in your life. Emmelyn VIncent explains why that's important and how you can start that process.
Preview Event: See the brand new CBD apartment range from Central Equity. More information inside.
If you're a new international student in Victoria, you've likely encountered the Student Welcome Desk at Melbourne Airport. Wing Kuang speaks to one of the desk's staff members and reveals why the Student Welcome Desk is important in building a positive international study experience.
With more than a decade of experience in the banking and financial advisory sector in her home country, former international student Alexis Phang faced a grim reality upon returning to Australia – the prospect of starting all over again. Now as a Mobile Relationship Manager at Bendigo Bank, Mihika Hegde catches up with Alexis to find out how she beat the odds and found her place in an organisation that values diversity.
How do you find a community to belong to and make new friends while you're at uni? Grace Kang offers you the ultimate guide on how to do so.
IN the first of our 'A day in the life of…' series, we profile GLoBALL's multicultural coordinator Salim Mahazi. He gives us some insight into AFL and how it can help bridge the gap between international and local students. Giulia Poloni tells us more.
IT is a requirement for students transitioning to the Temporary Skilled Graduate (subclass 485) visa to purchase private medical insurance. However, many are unaware they have many options to choose from when purchasing a medical insurance policy.
FIND out why Mad Mex is leading the Mexican food wave in Melbourne, and take part in a competition to win a free meal on the house for you and a friend!


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Franklin Mineral Museum has Fund-raiser
If you have already pleged toward the color book fund please sent it to the museum in care of the address below.
Donations may be sent to :
Franklin Mineral Museum
32 Evans Street,
Franklin, New Jersey 07416
(973) 827 3481
(Please be sure to specify that the denation is for "The Color Book Fund".)
The Franklin Mineral Museum in Franklin, Sussex County has started a fund-raiser that will achieve several goals. The first goal is to publish a color photographic art book showing the world-famous diversity of crystals and minerals the area is famous for. The book will be released for the 50th anniversary of the incorporation of the museum and its nature center. Many people have seen the sign on Route 23 when entering the town of Franklin: "Welcome to Franklin. The Fluorescent Mineral Capital of the World". While this claim is unchallenged, relatively few people have seen how beautiful fluorescent minerals are. The title of the book is "Franklin and Ogdensburg, New Jersey. A Photographic Celebration." The 500 page hardcover book will feature about 1000 pictures, many full page color photos, of the crystal treasures of the Franklin Region. Specimens from world-famous museums such as the Smithsonian, Harvard University, Yale University, and several important private collections will be featured. European photographers have been invited to contribute photographs from international collections. The project has been on-going since October, 2012 and will culminate in a celebration in September 2014.
Several photographers since the 1960s have tried to photograph the crystals of the area, but have not produced a manuscript. The Franklin Mineral Museum has had a color book fund for nearly twenty years, but there has been no suitable manuscript to publish. In October, the museum board decided to have such a book produced and contacted Van King and Peter Chin, both well-known authors of Franklin mineral articles to spearhead a project. The lead author has produced and published 20 books about minerals and crystals. Steven Phillips, of R. S. Phillips Steel, LLC in Vernon, has been soliciting private donations to increase the Museum's color book fund and to date has more than quadrupled the color book fund. The budget to print the book is $85,000 and to date he has raised nearly $50,000 from private donors. Fund-raising will continue into 2014. Donations may be made directly to the Franklin Mineral Museum, 32 Evans Street, Franklin, NJ 07416. A description of the project is at the link given above as well as at http://www.newryqs.com/Franklin.html. The latter link has several downloadable pdfs that show the early progress of the book. The final form will, of course, evolve by next year's deadline.
The production of a color book has been much desired for over the last half-century and the project is under way. The proceeds of the sales of the book will be used to increase the facilities of the museum. The long term plan includes up-grading display cases and lighting and changes to the building. The most valuable asset the Museum has for members of the general Franklin area is the park land they possess. The Museum would like to utilize that land in the form of nature trails, guided historical tours of the mining property, etc. Over 20,000 school children utilize the Museum's educational opportunities each year as well as a wide variety of local citizens and visitors. The fund raiser will make their plans a success.
Here is a short, low resolution, example of the A-Z layout. The photos will be improved as the project progresses, but the pattern will be similar. There should be over 1000 illustrations in the final book.
Download Sample Franklin Mineralogy Pages PDF
Download Sample Franklin Mineral Veins pdf
Donations may be sent to :
Franklin Mineral Museum
32 Evans Street,
Franklin, New Jersey 07416
(973) 827 3481
(Please be sure to specify that the denation is for "The Color Book Fund".)
Be sure to come visit the Franklin Mineral Museum in Franklin! The museum features a modern exhibit area of both Franklin and worldwide minerals. We have an outstanding exhibit of fluorescent minerals, historical exhibits, as well as an open-air nature area where you may walk as well as collect your own minerals if you wish. We look forward to seeing you! Please visit the Franklin Mineral Museum website:


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The Venetian painter and graphic artist Jacopo de'Barbari was born sometime in the mid-15th Century. Almost nothing is documented of his early life, and estimates of his year of birth vary from 1440 to 1470. It is thought that de'Barbari met Albrecht Dürer during the latter's first trip to Venice in 1495: it is presumed that the Venetian was a well-established painter and engraver by this time. A famous portrait of the mathematician Luca Pacioli, dating from 1495, has been attributed to de'Barbari, but the styling of the figures in this composition strikes me as quite unlike that in the artist's better-attested works. Another remarkable work credited to 'Meister Jakob' (as Dürer sometimes referred to him), is an elaborate map from an aerial perspective of the city of Venice, dating from about 1500.
De'Barbari's fame had evidently spread as far as Germany, as, in 1500, he was summoned to the Court of the Emperor Maximilian I. Thereafter, he lived in Nuremberg for at least a year, before moving on to Torgau, Naumburg, Wittenberg and Weimar. Dürer and de'Barbari renewed their acquaintance during the latter's German sojourn, and the Venetian also came into contact with Lucas Cranach the Elder. It is thought that many of the artist's surviving engravings date from his time in Germany. Also from this period, de'Barbari's Still-Life with Pheasant and Iron Gloves is the earliest known signed & dated pure still-life painting. Note that this canvas bears both de'Barbari's name, and the sign of the caduceus: on the engravings, this symbol takes the place of a signature.
In 1510 de'Barbari is mentioned as painter to the Duchess Margaret, Regent of the Netherlands. The following year, the Duchess granted him a generous pension. He died sometime between 1511 and 1516. Of his work, a few dozen engravings and a small number of paintings and woodcuts survive. Besides the still-life mentioned above, there is a painting of a Sparrowhawk (thought to be a detail cut from a larger canvas) by his hand at the National Gallery in London; a Madonna and Child (Between St John the Baptist and St Anthony) at the Louvre; and a striking Portrait of Christ at Weimar.
In his book Four Early Italian Engravers (my source for the present images), Tancred Borenius describes the figures in de'Barbari's engravings as having 'drooping attitudes' and 'langorous expressions' with 'long, softly gliding curves that seem an echo of Gothic art.'
Although most of the images I've chosen to present here have subjects drawn from Classical mythology, there are at least as many straightforwardly religious subjects in de'Barbari's graphic oeuvre. The present images are, from top to bottom: Triton and Nereid, Victory Reclining amid Trophies, The Man with the Cradle, A Satyr Playing the Fiddle, A Satyr with a Wine-Skin, A Centaur Pursued by Dragons, The Guardian Angel and Mars and Venus.
Click on the images to see them enlarged…Posted by misteraitch at July 23, 2004 12:14 PM | TrackBack
Bruce Sterling, via wired, gave me the link to your blog. Nice work.
re Barbari: I loved the Pacioli and the museum in Naples... how widespread is the doubt as to its painter? Barbari has been credited also as the first "Still Life" painter, which must be an overstatement...
From what little Ive read about it, it seems to me that the attribution of the Pacioli canvas to deBarbari is someones educated guess, although, who knows, there may be some documentary evidence too, which would clinch it. The attribution cant be a traditional one, or Im sure that Borenius would have mentioned it in Four Early Italian Engravers, which was written in the early 20s. To me, the figures in deBarbaris engravings (and also in the Madonna & Child painting and the portrait of Christ I link to above) have a certain odd, rather mediaeval look about them, which I dont see in the Pacioli picture. Of course, that proves nothing, and I am far from being an expert in these mattersPosted by: misteraitch on July 26, 2004 09:29 AM
Grazie for the fascinating link, Giovanni. I now understand, having read this page, how the Pacioli canvas came to be attributed to deBarbari: a cartiglio (a painted scrap of paper) on the right hand side of the table carries the inscription IACO.BAR. VIGENNIS. P. 1495, apparent abbreviated signature and ineluctable & unresolved cipher [crittographia] rendered even more ambigious by the superimposed representation of a fly [una mosca]. Certainly IACO.BAR. could be Jacopo de Barbari, although this still doesnt explain VIGENNIS. The page collects some circumstantial evidence in support of an attribution to Leonardo da VinciPosted by: misteraitch on September 28, 2004 11:24 AM
Great job !! I'm working on Jacopo's life and connections in Venezia.
Can you supply the bibliography you have used for your work.
Many Thanks
Gildo Venezia


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"We create attractive and accessible external spaces — vital in the creation of successful communities." Andrew Tindsley, chair of landscape
Whether urban or rural, the external environment helps to shape and define the places we live, work and spend our leisure time in. Our landscape architects are engaged with projects across the UK and overseas, protecting and enhancing the natural landscape or working with clients and communities to create 'smart' green masterplans, imaginative urban spaces, lively parks and attractive settings for new development. Our aspiration is to create landscapes which balance the needs of people with those of the wider environment
We are experienced designers in many sectors of the built environment, helping to create new landscapes for education, healthcare, retail, and workplace development, as well as enhancing the public realm in many of our urban centres. Our work starts by engaging with people, then retains them at the centre of the design process.
For further information please download our Landscape Architecture brochure on placemaking
Life + Art + Light + Soul = Place.
Jo is one of our landscape architects in Bristol studio. In this short video she tells us about her career in BDP.
Our architects, landscape architects and lighting designers collaborated as one to design and redevelop a previously unused area into a beautiful and tranquil new public space for people to visit and use.
The film documents the design process and the ideas behind this exciting project.
Our architects, landscape architects, lighting and sustainability consultants designed the pavilion as part of a team led by Nottingham-based artist Wolfgang Buttress and including contractor Stage One and structural engineer Tristan Simmonds.
Andrew is a principal and leader of the landscape architecture profession within the practice. He is responsible for BDP's London Urbanism Studio and chairs the Rotterdam studio.
Nick is a principal and co-manages architects, landscape architects, urban designers and urban planners in our London urbanism team.
Mehron is a landscape architect director in the London studio.
Martin is a landscape architect director and leads the landscape profession in the south west
James is a landscape architect director in our Manchester studio.
Urbanism director Anna Sinnott explains how engaging local people is at the heart of what we do, making our expertise available to them and combining our design skills with their in-depth local knowledge to co-produce great streets and public spaces.
Research by the LSE Cities Unit recently concluded that whilst the average population growth of 200 world cities in the period 1990 to 2050 was likely to be 300%, the physical footprint of those cities would increase by 500%.
Plans for a £300m extension to the Meadowhall shopping centre in Sheffield have been approved. The new Leisure Hall will add a range of dining and entertainment experiences not currently available at the centre. These include new restaurants, a state-of-the-art cinema, a new café court, gym and other leisure space.
The Mayor of Yancheng and central Chinese government have selected BDP from a shortlist of five practices to develop Yancheng in south China.
BDP works closely with artists and recent collaborations have been on projects such as Alder Hey Children's Hospital, The Hive at Kew, Grosvenor estate in Mayfair and Royal Pharmaceutical Society.
This year we have five projects shortlisted in the AJ Retrofit Awards. We are delighted to have the most projects shortlisted than any other practice.
BDP has completed a new flagship building for Manchester Science Partnerships (MSP). The 70,000 sq ft Bright Building is the new headquarters for CityVerve, Innovate UK's Internet of Things city demonstrator, as well as the home to various tech businesses.


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- 2010
In this article we study a two-phase cell division model. The cells of the two different phases have different growth rates. We mainly consider the model of equal mitosis. By using the semigroup theory, we prove that this model is well-posed in suitable function spaces and its solutions have the property of asynchronous exponential growth as time approaches… (More)
Yaw dynamic model of a miniature unmanned helicopter is needed to develop for heading control. A yaw dynamic model is deduced based on miniature unmanned helicopter characteristics in hover. Different from a large helicopter, the yaw damping system of a miniature helicopter is realized through the negative feedback of helicopter heading rate, which is… (More)
In this paper we study the two-phase size-structured population model with infinite states-at-birth and distributed delay in birth process. The model distinguishes individuals by two different status: the 'reproductive' stage and the 'nonreproductive' stage. We establish the well-posedness for this model and show that the solution of this model exhibits… (More)
- Meng Bai, Xiaoguang Zhao, Zengguang Hou, Zhiqiang Cao
- 2008 7th World Congress on Intelligent Control…
- 2008
For low-cost SINS/GPS integrated navigation system using low precision inertial sensors, the psi-angle model of SINS will degrade the performance of a designed filter due to the neglected error terms in the model. A general SINS error propagation model based on quaternion is presented. The error model is nonlinear and does not rely on small misalignment… (More)
- Meng Bai, Xiaoguang Zhao, Zeng-Guang Hou, Min Tan
- 2006 6th World Congress on Intelligent Control…
- 2006
A novel negative selection algorithm is presented, which is inspired by the negative selection mechanism of the immune system that can detect foreign patterns in the complement (nonself) space. In the algorithm, the pattern space is unified into a certain interval and the foreign pattern detectors (in the complement space) are defined in the form of short… (More)
- Meng Bai, Min-hua Li
- Proceedings of the 10th World Congress on…
- 2012
The dynamic model of a miniature unmanned helicopter is needed to develop for autonomous helicopter flight. A subspace identification method for the roll and pitch coupling model is proposed. The roll and pitch coupling model of a hovering miniature unmanned helicopter is deduced to obtain an identification model structure for use in the subspace method.… (More)
For SINS/GPS integrated navigation system with unknown measurement noise covariance matrix, adopting the conventional Kalman filtering approach to estimate the navigation system errors will lead to a large state estimation error or even make the filter diverge. To solve this problem, an adaptive sequential Kalman filter is presented, in which the… (More)


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Amazon Underground Has Tripled Number Of Available Apps
At the end of August, Amazon dropped a bomb on the android app eco-system when it announced Amazon Underground, an app that contains thousands of apps, valued over $10,000, for free. Today it is being reported that developers who have put their apps in Amazon Underground are seeing significant revenue spikes, and the amount of apps available have tripled since the launch.
The Amazon Underground app operates just like the traditional Amazon Shopping app, only it has an extra "Underground Apps" tab where you can download the likes of Goat Simulator, Shadow Gun, Monument Valley, Duck Tales Remastered, and thousands more at absolutely no cost. Even the extra bonuses, items and additional levels that would previously be in-game purchases are included for free. Amazon has made it possible to give users all these apps for free by entering a mutually beneficial arrangement with the developers. Amazon pays developers $.002 for every one minute users spend in the app, and the free apps draw users to the Amazon eco-system. It may not sound like the developers are receiving much money, but when you are talking about thousands of addicted Angry Birds players fanatically replaying levels, it equals enough that Rovio is reporting its profits have tripled since adding their products to Amazon Underground.
Rovio isn't the only app makers seeing this new distribution method pay off in big ways. Halfbrick Studios, the developers behind Jetpack Joyride and Fruit Ninja told Business Wire "Thus far we have doubled the downloads and revenue from our apps in the Amazon Appstore and most interestingly, customers are engaging with our in-app purchase content within our games at an extremely high rate. Since all in-app purchases are free in Amazon Underground, they can play the games in new and exciting ways."
Amazon Underground works on Amazon's Fire tablets as well as Android phones and tablets—and that is really the play here isn't it? Amazon's move here isn't all that surreptitious, as it being seen as a way for Amazon to up the ante and offer something that is not offered through the Google Play Store. If Amazon Underground continues its rise in popularity, (which is probably just an issue of alerting users to its existence) how does the Play Store compete against 'free'? Which also begs the question, how long can Amazon afford to pay developers for apps that the company is not making money on? If Amazon Underground becomes the primary source for downloading apps, eventually Amazon has to make revenue in order to pay for these apps. It's hard to say what the company's plans for the future are, but this experimentation is certainly beneficial for users and developers in the here and now.


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Comical Hummer, crazy over fountain spray
About This Image
hummingbird, Rufous female, comical capture, looking like she's crazy over the spray from the fountain.
captured from open front window.
toddM Very comfortable rooms and ateosphmre. Stayed here over the weekend with my wife for our anniversary. She got a mani/pedicure & updo at their spa that's at the location, before we went out to dinner & tuacahn one night. Will definitely be returning. Better than any cold hotel we've ever stayed in.Thanks ah bella
many thanks, Kathy, happy you like them : ) and thanks for taking time to leave a nice comment.
Great shot Alandra! Love all your hummingbird pics.
Great capture...I love hummingbirds too...~~ Karen
thankyou Ikka, yes that one was quite sometime ago now. They have now visited us for another summer and have left us again. They will return in March next year
Long time ago... Unsual, but extraordinary scene: I like it very much.
thanks Alex D for the nice comments.
Pretty wonderful shot. This one is really "head on" and quite unique.
Hi Fotonaut, - is this Derek? sorry but am not sure if I've remembered your name correctly, - anyway, good to hear from you and thankyou very much for the nice comments and help. Will hafta start learning more about the settings, it's something am not at all familiar with : ) - but wish I did know about.
thanks May, yes, I guess I'll hafta curb my addiction for hummer shots, lol, -- guess I'd better put my other lens on the camera for a change and take some scenery shots, LOL.
Phenomenal front angle Alandra! If you can jam with a faster shutter speed, maybe 4000, you should be able to freeze the wings.
You and your hummingbirds! They're wonderful!
glad you like it, Janice and Beverly. It is a strange capture. It almost looks to be "fierce" : )
many thanks, Carol and Alex. Strange about your hummers not being interested in the water. Ours go crazy over it, as you see from the pics
Very unusual capture. Good job.
That is an excellent shot. Wow it is coming straight at you. Like she is dodging the water.
WOW!! what a great shot,ours don't seem to be a bit interested in either of the bird baths we have out.
Nice capture of hummer!!! Carol
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Small Business Operations Understanding The Product
Where is Coffee Grown? Coffee trees produce their best beans when grown at high altitudes in a tropical climate where there is rich soil. Such conditions are found around the world in locations along the Equatorial zone.
Coffee Exports in Tons Brazil2,249,010 Vietnam961,200 Colombia697,377 Indonesia676,475 Ethiopia325,800 India288,000 Mexico268,565 Guatemala252,000 Peru225,992 Honduras217,951 Côte d'Ivoire170,849 Uganda168,000 Costa Rica124,055 Philippines97,877 El Salvador95,456 Nicaragua90,909 Papua New Guinea75,400 Venezuela70,311 Madagascar62,000 Thailand55,660 World7,742,675
The Discovery of Coffee According to legend, coffee was discovered around 850 AD by an Ethiopian goat herder named Kaldi. He noticed that his goats acted in an unusually spirited manner after eating the red cherries of a nearby shrub. Kaldi also ate the cherries and enjoyed the extra energy that they gave him. These shrubs grew in an area of Ethiopia called "Kaffa" and the shrubs were called "Kafa," which is one possible root word for the modern word coffee.
The History of Coffee Local people gathered the coffee beans from the trees that grew in the region, ground them up and mixed them with animal fat, forming small balls that they carried as rations on trips. Other tribes of Ethiopia ate the beans as a porridge or drank a wine created from the fermented crushed coffee beans. The local monks soon started eating the berries as a means to help them to stay awake during long periods of prayer. The monks went on to find that, if they were crushed and infused with water, the berries could produce a (probably cold) drink that gave a similar stimulating effect. From Ethiopia, coffee plants spread to the Arab world where they were heavily cultivated.
Coffee History Continued Around 1550 the first coffee houses opened in Istanbul, Turkey From the Arab world, the coffee drink spread to Europe where it replaced beer as the most popular breakfast beverage. (People could not drink water because of bacteria in the water.) In 1652 the first coffee house opened in London, soon over 2,000 coffee houses existed in the city. These became gathering houses for intellectual and political discussion. The actual word "coffee" appears to have entered the English language some 400 years ago from the Italian 'caffe'.
Coffee Facts The coffee bean is actually the dried seed of the coffee tree cherry.
Coffee Facts There are two main species of the coffee plant: Arabica and Robusta. ◦ Arabica coffee is the superior plant. Arabica beans are the bean of choice in "gourmet" or "specialty coffees". ◦ Arabica coffee beans produce the rich flavor and body found in a good cup of coffee. ◦ Robusta coffee plants lacks this flavor and body. ◦ The Robusta species is a hardy, high yielding plant resistant to the numerous pests, which afflict coffee. ◦ Robusta coffees have higher caffeine content than Arabica; up to twice as much caffeine. ◦ Robusta is not usually consumed by itself, due to its bitter and acidic flavor. ◦ Sometimes a small amount of Arabica will be blended with a larger portion Robusta.
Coffee Trivia The largest retailer of coffee in America is Dunkin Donuts, which sells about a billion cups a year, or 30 cups every second.
Coffee Trivia The only American state to grow coffee is ?
All coffee beans imported to the US are "green" and have a shelf life of up to one year. Green coffee beans Roasted coffee beans will darken, plump, and lose weight as they are roasted. Darker roasted coffee, which indicates a longer roasting time, reduces the amount of caffeine in the coffee.
Coffee Trivia One of the most expensive coffees in the world is Kopi Luwak from Indonesia. It's made from coffee beans digested and excreted by the palm civet, a catlike animal, and sells for around $300 per pound.
Coffee Trivia Today, more money is spent on the international trade of coffee than on any other commodity except oil.
What is "Organic" Coffee? Organic coffee is coffee that has been grown according to organic farming techniques, without the use of artificial fertilizers, pesticides or herbicides.
What is "Fair Trade" Coffee? Coffee farmers are guaranteed fair prices. There is a minimum price of $1.26 for one pound of coffee, Both workers and farmers have the right to fair labor conditions. This includes the freedom of association, safe conditions, and livable wages. Fair trade requires direct trade between the coffee producer and the coffee importer. No middle man is allowed to step in to take a portion of the profit. Fair trade farms are run democratically - all employees are involved in the process. The farmers choose how to re- invest their trade revenues. Fair trade certification expects community involvement by the farms. A portion of trade revenues are invested into social projects, in education, or for organic certification.
What is "Shade Grown" Coffee? "Shade Grown" coffee is sometimes referred to as Bird Friendly coffee. Recently larger farms have clear cut forests to grow coffee in full sun conditions. This has had negative effects on the environment and the birds. The quality of the coffee has also been negatively effected. In the past, coffee has naturally been grown in shady conditions.
What is Espresso? Espresso is a concentrated coffee beverage brewed by forcing hot water under pressure through finely ground coffee.
What is Crema? Crema is the golden red froth on top of a well prepared espresso.
The Espresso Machine The first espresso machines were patented in 1901 in Italy. Espresso has a thicker consistency than regular coffee. As a result of the pressurized brewing, all of the coffee flavor is very concentrated. For this reason, espresso is the base for other drinks, such as lattes, cappuccino, macchiato and mochas.
Modern Espresso Machine A 1 fluid ounce shot of espresso has about half the caffeine of a standard cup of drip brewed coffee.
Espresso Terms Barista – The coffeehouse equivalent to a bartender. "Pulling a Shot" – Preparing espresso, so named because early espresso machines required the barista to pull down on a lever. Portafilter – The handled device on an espresso machine that holds the metal basket and coffee grounds. Group or Grouphead – The area that a portafilter locks into on an espresso machine. Tamper – A heavy tool used to pack espresso grounds. Knockbox – A small portable pan with a bar across the top. The barista taps the portafilter against the bar to remove the espresso puck. Steam Wand – Device on the espresso machine used to heat milk. Steam Pitcher – A stainless steel pitcher that holds milk for steaming.
Cup Warmer Grouphead Portafilter Steam wand
What is the Correct Temperature for Brewing Coffee? The correct temperature for brewing coffee is 195 to 205 Degrees Fahrenheit. Most drip coffee makers brew coffee at lower temperatures. Keeping a pot of coffee on a warming plate damages the flavor of the coffee after 30 minutes. It is best to keep brewed coffee in a pre-heated thermal carafe.
How should ground coffee or coffee beans be stored? The best way to store coffee is an air- tight container in a cupboard. Both light and air speed the oxidation and drying of your beans, which result in flavor loss and also loss of ability to make good crema.
How is coffee decaffeinated? The process is usually performed on unroasted (green) beans, and starts with steaming of the beans. The beans are then rinsed with a solvent that removes the caffeine without removing the coffee flavor.
Basic Coffee Drinks Café Au Lait – Made from equal portions of steamed milk and strong brewed coffee. Macchiato is a shot of espresso with a small amount of hot, foamed milk on top. Cappuccino – Made with espresso and steamed milk and topped with milk froth. ◦ Flavored syrup is often added to a cappuccino. Latte – An espresso drink combined with steamed milk. ◦ Flavored syrup (vanilla, caramel, hazelnut, etc.) can be added or ◦ Chocolate syrup/sauce can be added resulting in a drink commonly called a Mocha. Ristretto – A short or restricted shot of espresso, usually ¼ to 1 ounce. Lungo – A long shot of espresso between 1 ½ and 2 ounces. Hot Chocolate – Chocolate syrup/sauce and steamed milk.
Turkish Coffee Turkish coffee is coffee prepared by boiling finely powdered roast coffee beans in a pot, possibly with sugar, and serving it into a cup, where the dregs settle. The name describes the method of preparation, not the raw material; there is no special Turkish variety of the coffee bean.
Video: Modern Marvels The History of Coffee
End: Product Knowledge Unit Visit the website www.quizlet.com to review the terms associated with this unit of instruction. If you have not already done so, create an account with Quizlet.com. Use your first and last name (without a space) as your login. Use your first name (or anything you can remember!) as your password. Using the Quizlet.com search feature, search for cdorman and find Mr. Dorman's dashboard. Open the Subjects folder "Small Business Operations." Study the flashcards. Use the test feature and use the scatter feature.
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Hello Folks,…The Sony company it will hold a press event on September 2. As for the devices to expect at the event, the Xperia Z5 along with the Sony Xperia Z5 Compact seem likely for a number of reasons.
Sony Xperia Z5 With Fingerprint Scanner Specs And Price
the Sony Xperia Z5 is likely to sport a 5.5-inch display. Sony might also opt for the Snapdragon 810 v2 chipset. On the camera front, the Xperia Z5 is purported to have a 21-megapixel IMX230 sensor and an 8-megapixel sensor placed upfront for taking selfies.
Interestingly, a purported image of the Sony Xperia Z5 The image suggest that both phones will have fingerprint scanners, which will be embedded on the power button. Interestingly enough, the leakster says that neither of the phones will have the USB Type-C port.
Full Specification of Sony Xperia Z5
- Display : 5.5 inch screen and 4K Resolution
- Processor : 3.2 GHz Octa Core 64bit Qualcomm Primary
- Camera : 30 MP with G+ sensors
- Front cameras : 10 MP with Face-Detection
- Internal Storage Capacity : 128 GB
- Battery : 4500 mAh battery with fast charging
- Os Android Lollipop
Sony Xperia Z5 Features :
- 4K ultra HD display
- Finger print sensors
- Retina scanner
- Gravity sensors
Sony Xperia Z5 Price :
Price in india: 55k INR