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Seratrodast [7-Phenyl-7-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dien-1-yl)heptanoic acid] is a thromboxane A2 (TXA2) receptor {TP receptor} antagonist marketed as an antiasthmatic drug with inhibitory effects on immediate asthmatic reaction in asthma and airway hypersensitivity. It also has antagonistic effects on contractile prostanoids, including PGH2, PGF2α, PGD2, and 11β- PGD2. Thus this drug is expected to have a wide range of antagonistic effects on bronchoconstriction mediators [1, 2].
|2D and 3D Structure for Seratrodast
Chemically, it is a quinone derivative with a long alkyl chain ending in a carboxylic acid, making it poorly soluble in water. It is a chiral molecule, though marketed as a racemate, studies report the best activities in the following order of descent: R–enantiomer, racemate and finally S–enantiomer. It is a novel design, orally active, potent and long acting TP/PGH2 receptor antagonist.
Seratrodast does not affect thrombus formation, time to occlusion and bleeding time. Seratrodast has no effect on prothrombin time and activated partial thromboplastin time, thus ruling out any action on blood coagulation cascade [1].
It was the first TP receptor antagonist that was developed as an anti-asthmatic drug and received marketing approval in Japan in 1997. Seratrodast is currently marketed in Japan, China and India (approved in December 2012) as an add-on controller therapy in the management of asthma.
Pharmacological Importance of Thromboxane and Prostaglandin
Thromboxane (TX) A2 and prostaglandin (PG) I2 (prostacyclin) are two of the metabolites of arachidonic acid produced through the cyclooxygenase pathway. These two compounds produce potent but opposite effects on smooth muscle and on platelets. Thromboxane A2 (TXA2) is a type of thromboxane that is produced by activated platelets and has prothrombotic properties: it stimulates activation of new platelets as well as increases platelet aggregation. Prostacyclin (also called prostaglandin I2 or PGI2) is a prostaglandin member of the eicosanoid family of lipid molecules. It inhibits platelet activation and is also an effective vasodilator [3].
The production of thromboxane and/or prostacyclin has been altered in patients with various diseases, such as unstable angina, glomerular disease secondary to systemic lupus erythematosus, systemic sclerosis complicated by Raynaud's phenomenon, septic shock, and asthma. Increased levels of TXA2 metabolites have been found in the urine and in bronchoalveolar lavage fluid of atopic asthmatics after allergen challenge. These data suggest that treatment with an agent that inhibits TX synthesis or blocks TX receptors could have beneficial effects in these pathologies.
Seratrodast blocks the broncho-constrictor effects of prostaglandins in the body. Seratrodast also decreases the inflammation by antagonising the thromboxane A2 receptor. Addition of a TXA2 receptor antagonist to conventional antiasthma medications may be considered in the management of patients with mild to moderate asthma having increased airway secretions.
Mechanism of Action
Seratrodast, a quinone derivative, is a novel, potent, orally active, and long acting TXA2/PGH2 receptor antagonist. In addition, Seratrodast has PGF2α, PGD2, and 9α, 11β -PGF2 antagonistic effects [1, 4].
The specificity of Seratrodast at antagonizing the TXA2 receptor was tested in vitro, ex vivo, and in vivo. Because of the short half-life of TXA2 (about 30 s), more stable analogs such as U-46619 and U-44069 were used to study the antagonistic effect of Seratrodast on TXA2 receptors. Similar to TXA2, such analogs exert a potent platelet-aggregating and smooth muscle contracting effect. Several studies in animals were conducted to investigate the pharmacological effects of Seratrodast in these areas and its antagonistic effect on the TXA2 receptor.
The specific binding of Seratrodast to platelets was tested in guinea pigs and humans. Seratrodast inhibited the specific binding of [3H]U-46619 to washed guinea pig platelets with an IC50 value of 0.0082 uM. This inhibition was more effective than the inhibition produced by unlabeled U-46619 (IC50 = 0.037 uM). Moreover, the antagonistic effect of Seratrodast was tested on the human TXA2 receptor genetically introduced into Chinese hamster ovary (CHO) cells. Seratrodast competitively inhibited the specific binding of TXA2 mimic ( [3H]U-46619) to the ovary cells with an IC50 of 0.06 uM, indicating that the drug is an antagonist of human TXA2 receptor [1, 4].
Seratrodast had neither an anti- Leukotriene D4 (LTD), nor an anti- platelet-activating factor (PAF) activity at 100 uM (guinea pig lung membranes) or 10 uM (rabbit platelets), respectively.
The specific antagonism of Seratrodast against the different enzymes involved in arachidonic acid metabolism was also tested. Seratrodast inhibited the production of 5-hydroxyeicosatetraenoic acid from arachidonic acid (5-lipoxygenase antagonism) by rat basophilic leukemia cells with an IC50 value of 0.21 uM. A very weak inhibitory effect of Seratrodast was reported on thromboxane synthetase (horse platelet, 13% inhibition at 10 uM) and cyclooxygenase (bovine vesticular gland, 20% inhibition at 100 uM).
Dosages and Approvals
Seratrodast (Tradename: Bronica) was approved in Japan in 1997 for treatment of bronchial asthma at once daily doses of 80 mg to be administered after dinner. Subsequently China and India (in 2012) have approved the drug an add-on controller therapy in the management of asthma. Seratrodast has been well tolerated following repeated once daily oral doses of up to a maximum of 320 mg. In elderly patients it is recommended that the treatment should be started with a lower dose of 40 mg/day. Phase trials were carried out in the west but it has not been approved by EU or US till date.
Seratrodast was discovered, developed and launched by Takeda Pharmaceuticals, Japan.
Seratrodast was discovered, developed and launched by Takeda Pharmaceuticals, Japan.
Reported Activities for Seratrodast
Platelet Aggregation: In the in vitro studies, Seratrodast inhibited the aggregation of guinea pig platelets induced by a prostaglandin endoperoxide (PGH,) analog, U-44069, arachidonic acid, or collagen in a concentration-dependent manner with IC50 values of 0.31, 0.49 and 0.23 uM respectively. Seratrodast did not affect the platelet activating factor (PAF) or adenosine-5'-diphosphate (ADP)-induced aggregation. Seratrodast at a concentration of nearly 900 uM did not induce shape change or platelet aggregation, indicating that it has no agonistic action.
In ex vivo experiments, Seratrodast by oral administration (0.1-1.0 mg/kg) inhibited in a dose-dependent manner the platelet aggregation induced by U-44069 in guinea pigs and the rabbit platelet aggregation induced by arachidonic acid [1].
Antithrombotic effect: The activity of Seratrodast was also tested in male New Zealand rabbits were common carotid artery thrombosis induced by endothelial damage was significantly inhibited by oral administration of seratrodast. Seratrodast had little effect (16%) on increased plasma concentration of 11-dehydro TXB2 a stable metabolite of TXA2.
The in vivo antithrombotic effect of Seratrodast was significantly correlated (p < 0.01) with its ex vivo inhibitory effects on arachidonic acid-induced platelet aggregation in rabbits. This correlation suggests that Seratrodast produce its antithrombotic effect by inhibiting the binding of TXA2 to the receptor [1].
The prothrombin time and activated partial thromboplastin time were not affected by high doses of Seratrodast (10 mg/kg), ruling out any direct inhibition of blood coagulation cascade.
Vascular Smooth Muscle: Seratrodast competitively inhibited the contractile response to U-46619 in guinea pig lung parenchymal strips and dog saphenous vein strips with pA2 mean values of 8.29 ± 0.09 and 6.79 ± 0.05, respectively. Similarly, Seratrodast competitively inhibited the contraction of rabbit aorta and pig coronary arteries induced by U-44069 with pA2 values of 8.3 and 9.0, respectively. Seratrodast also inhibited the contraction of rabbit aorta induced by PGF2α (pA2 = 7.8) and the contraction of pig coronary arteries induced by PGF2α, PGD2, and 9α, 11β -PGF2 a metabolite of PGD2 with pA2 values of 7.8, 8.6, and 7.8, respectively [1].
Airway bronchoconstriction and asthma: Seratrodast competitively inhibited the contractile response to U-46619, PGD2, and 9α, 11β -PGF2 or PGF2α with pA2 values of 7.69, 7.20, 7.79, and 5.71, respectively. The contractile responses of guinea pig tracheal strips to leukotriene D4 (LTD4) or platelet activating factor (PAF) were not inhibited by Seratrodast. Seratrodast given orally inhibited the bronchoconstriction in guinea pigs induced by U-46619 (10 ug/kg, i.v.), LTD4 (10 ug/kg i.v.), or PAF (1 ug/kg i.v.). Seratrodast did not inhibit bronchoconstriction induced by histamine (10 ug/kg i.v.) in guinea pigs [1].
The effects of racemic Seratrodast and its enantiomers were compared in vitro and in vivo. In vitro, racemic Seratrodast and the R (+)-enantiomer were more potent than the S(-)-enantiomer. Also, oral administration of racemic Seratrodast and the R(+) enantiomer showed very potent inhibitory effects on U-46619-induced bronchoconstriction in guinea pigs in vivo (minimum effective dose (MED] = 0.3 mg/kg), whereas the S(-)-enantiomer was much less active (MED = 20 mg/kg).
Activities for racemic Seratrodast, R-enantiomer and S-enantiomer
pA2 (Inhibiting U-44069-induced contractions of rabbit aorta) = 8.28, 8.60 and 6.64
pA2 (Inhibiting U-46619-induced contraction of the guinea pig lung) = 8.29 ± 0.09, 8.80 ± 0.10 and 6.53 ± 0.09
IC50 (Inhibition of U-44069-induced aggregation of guinea pig platelets) = 0.35, 0.12 and 13 uM
IC50 (Inhibiting specific binding of [3H]U-46619 to guinea pig platelets) = 0.0074, 0.0021 and 0.21 uM
Common name: AA-2414; AA2414; AA 2414; ABT-001; A-73001; Abbott-73001; Seratrodast
Trademarks: Bronica
Molecular Formula: C22H26O4
CAS Registry Number: 112665-43-7; 103187-09-3 (R-isomer); 103196-89-0 (S-isomer)
CAS Name: 7-phenyl-7-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dien-1-yl)heptanoic acid
Molecular Weight: 354.44
InChI Key: ZBVKEHDGYSLCCC-UHFFFAOYSA-N
InChI: InChI=1S/C22H26O4/c1-14-15(2)22(26)20(16(3)21(14)25)18(17-10-6-4-7-11-17)12-8-5-9-13-19(23)24/h4,6-7,10-11,18H,5,8-9,12-13H2,1-3H3,(H,23,24)
Mechanism of Action: Thromboxane A2 (TXA2) receptor antagonist; Prostaglandin H2 (PGH2) receptor antagonist
Activity: Management of asthma; Anti-asthmatic drug; Anti-inflammatory; Non-antihistaminic
Status: Launched 1997 (Japan)
Chemical Class: Small molecules; Benzene containing; Carboxylic acid containing; Long chain alkyls; Quinone derivative
Originator: Takeda Pharmaceuticals/Abbott Pharma
Seratrodast Synthesis
J Med Chem 1989, 32(9), 2214 – 2221: This is the first reported synthesis for Seratrodast and its various analogous. The article also reports various activities for the compounds. It is most cited reference for Seratrodast synthesis.
Friedel–Crafts acylation of benzene with the acid chloride from monomethyl pimelate leads to the keto acid. The ketone is then reduced to the alcohol with borohydride; saponification affords the corresponding hydroxyl acid. Treatment of that intermediate with the hydroquinone in the presence of boron trifluoride probably results initially in loss of the hydroxyl group to form the benzylic carbocation. This then attacks the electron-rich hydroqinone ring to form the coupling product. The newly added ring oxidizes to a quinone either in the course of the reaction or on workup to afford Seratrodast. Also see Ref. 6.
|1H NMR (Estimated) for Seratrodast
Experimental: To be filled later.
Sideeffects: The most commonly reported adverse reaction (AEs) by less than 5% participants include rash, itching, dysgeusia, anemia, eosinophilia, drowsiness, headache, dizziness, lightheadedness, palpitations and fatigue. Very rare or uncommon AEs include hot flashes, edema, insomnia, tremor, numbness, thrombocytopenia, nose bleeding, vomiting and bleeding tendency of subcutaneous hemorrhage.
Intake of Seratrodast can result in severe liver dysfunction with elevated AST (GOT), ALT (GPT). Few cases of jaundice in participants are also reported (0.2%). Also, fulminant hepatitis (in less than 0.1% participants) has been reported. Carefully monitoring, such as performing a liver function tests on a regular basis (once a month) is suggested. If any abnormalities are observed, administration should be discontinued with appropriate treatment.
The starting dosage in elderly is 40 mg with regular liver function checks. Though there are no reports on safety during pregnancy but Seratrodast should be avoided by lactating mothers. Pregnant women should be prescribed only if the therapeutic benefit is determined to exceed the risk.
Seratrodast has never been tried and approved for pediatrics use.
Others: A computational docking study is reported using the crystal structure of Seratrodast with a model for the human receptor (TXA2). The human TXA2 receptor was constructed on the basis of its amino acid sequence [7]. The approach though is qualitative but was able to prove the binding of the R isomer (total energy = -73.10 kcal/mol) to the TXA2 receptor is favored with respect to the binding of the S isomer (total energy = -70.21 kcal/mol). As, this was consistent with biological data, hence the binding model was used as starting point to docking studies of new antagonists within the aryl sulfonamide family with the modeled human TXA2 receptor.
A generic drug manufacture in India has published computational docking pictures for Seratrodast with TXA2 from Indian gene pool. No results are shared other than that Seratrodast is suitable for Indian people (here). No binding energies results are shared. Moreover, the difference between TXA2 from Indian gene pool v/s that from Japanese or European gene pool is not described. It appears to be an in-house effort with everything to hide and nothing to share.
1. Samara, E. E. Seratrodast (AA-2414)-A Novel Thromboxane-A, Receptor Antagonist. Cardiovascular Drug Reviews 1996, 14(3), 272 - 285. (FMO only)
2. Horiguchi, T.; et. al. Study on the Usefulness of Seratrodast in the Treatment of Chronic Pulmonary Emphysema. Drug Res 2002, 52(10), 764 - 768. (FMO only)
3. Prostaglandins and Thromboxanes. Butterworths Monographs in Chemistry. Butterworth and Co (Publishers) Ltd, 1982. (FMO only)
4. Shiraishi, M.; et. al. Quinones. 4. Novel eicosanoid antagonists: Synthesis and pharmacological evaluation. J Med Chem 1989, 32(9), 2214 - 2221. (FMO only)
5. Kuninobu, Y.; et. al. Indium-Catalyzed Synthesis of Keto Esters from Cyclic 1,3-Diketones and Alcohols and Application to the Synthesis of Seratrodast. Chem. Asian J. 2010, 5, 941 – 945. (FMO only)
6. Lednicer, D. Drugs based on a substituted benzene ring. Chap. 2: Strategies for Organic Drug Synthesis and Design, Second Edition. John Wiley & Sons, Inc., 2009. (FMO only)
7. Wouters, J.; et. al. Antagonism of the txa2 receptor by seratrodast : a structural approach. Bioorg Med Chem Lett 1999, 9, 2867 – 2870. (FMO only)


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Woolworths/Safeway: 10cents Per/Litre off on $30 spend this weekend or 8cents off P/L off til25nov11
Just saw an add on tv, advertising 10cents per/litre off when u spend $30 at Woolworths/Safeway this weekend only. Dont really know when Woolworth/Safeway think the weekend start tho might not be available til saturday, website is advertising 8cents per/litre off at the moment (thats valid til 25th November 2011). Im in VIC dont know if this offer is Australia wide.
Also if u spend $5 in store u will get a further 4cents per litre discount.
TOPICS: Shopping
1 comment
- queenshrewGreat! I only have a Caltex near me....:)

subset: commoncrawl


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Dealing with a host of primary wholesalers, multiple DSD vendors and local foodservice providers, convenience store chains are learning to grow more efficient without sacrificing goods and services. By Pat Pape, Contributing Editor Like millions of Americans, Matt Paduano was traveling this summer, but he didn't return home with a sun tan and postcards from
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As their popularity soars in convenience stores, e-cigs are becoming the target of new smoking bans and tax regulations. By Erin Rigik, Associate Editor. Once speculated to be a passing fad, e-cigarettes are increasing in sales and popularity and pushing their way toward becoming a mainstream product. Celebrities from Leonardo DiCaprio to Britney Spears have
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Exceptional leadership, great stores and unsurpassed customer service are the hallmarks of the convenience store industry's extraordinary chains. Following these guiding principles, Convenience Store Decisions is proud to announce Rutter's Farm Stores as the 2010 Convenience Store Chain of the Year. At a time when many industry marketers are struggling with exorbitant credit card fees
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The Fly Flew in (Library Binding)
Holiday House, 9780823424184, 1pp.
Publication Date: August 1, 2012
A fly enters a concert hall and causes a commotion among the audience and performers alike in this funny and easy-to-read picture book. In the wake of a fly's flight, a wig flips, eyeglasses fall, and a lollipop is launched. Musicians BANG and BOOM as they try to get that fly All fail, and the chaos culminates when an overzealous singer, flyswatter in hand, leaps off the stage. The audience applauds enthusiastically for the greatest display of showmanship they have ever seen.
David Catrow pays homage to the slapstick films of the last century with masterfully rendered artwork and an understated text that has a music of its own.


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Raines, DLP HDTV Team Finish 26th at Dover DOVER, Del., (June 4, 2006) - For Tony Raines and the No. 96 DLP HDTV team, the "Monster Mile" at Dover International Speedway lived up to its name in Sunday's Neighborhood Excellence 400 NASCAR NEXTEL...
Raines, DLP HDTV Team Finish 26th at Dover
DOVER, Del., (June 4, 2006) - For Tony Raines and the No. 96 DLP HDTV team, the "Monster Mile" at Dover International Speedway lived up to its name in Sunday's Neighborhood Excellence 400 NASCAR NEXTEL Cup Series event. Raines finished the 400-mile race in 26th, two-laps down to race winner Matt Kenseth.
After starting the race in 32nd, Raines immediately began complaining of an extremely loose machine. "This car is slicker than anything I've driven in a long time," said Raines. "I can't keep up with it. It keeps traveling away from me."
On lap 37 while running side-by-side with the No. 32 car of Travis Kvapil, Raines could only hold on for so long. The DLP HDTV Chevy spun. Rained managed to keep it off the wall, but the end result was the first caution of the day.
Crew chief Phillipe Lopez ordered four tires and a track bar adjustment to tighten up the car, but Raines would restart the race 41st, one lap down.
However, a long green flag run was just what the doctor ordered.
With the restart on lap 41, the No. 96 machine still seemed to be too loose for Raines' liking. But by the middle of the long run, the DLP HDTV team began posting lap times as quick as the leader. The only problem was that the team was playing catch-up. Being a lap down early at any track is hard to overcome, but especially so at Dover where the race leaders set a grueling pace.
The long green flag run came to an end on lap 116 for debris on the race track. Raines pitted for four tires and fuel, but shortly thereafter, Lopez brought him back onto pit road out of concern for a right front tire rub. The over-the-wall team changed two tires and raised the hood to determine where the tire rub was happening, then sent the No. 96 out to rejoin the field. Raines would remain one lap down and in no position to get his lap back.
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"We just kept playing with the car all day," said Raines. "It was good on a long run, but we just started too far behind the curve. I'm really looking for a top-15. We'll just go to Pocono next week and do the best we can."
Kenseth's win was his 12th career Nextel Cup victory and his second of the season. Jamie McMurray finished second, while Kevin Harvick, Jeff Burton and Kyle Busch secured the rest of the top-five. Jimmie Johnson, Kasey Kahne, Greg Biffle, Mark Martin and Dale Earnhardt Jr., comprised the rest of the top-10.
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This property has been removed by the agent. It may be let or temporarily removed from the market
Property Description
Letting information:
|Added on Rightmove:
|24 February 2016 (578 days ago)
Full description
This stunning, contemporary two bedroom flat is located in block with gated parking, immaculately kept block with lift. The property comprises bright reception room with double doors to balcony open plan with well equipped kitchen, master bedroom with fitted wardrobes and en-suite , one further double bedroom and lovely contemporary guest/familybathroom. The property is in a fantastic location in sought after South Croydon, with many shops, restaurants and entertainment on its door step. For transport South Croydon Station is within a short walk, whilst the motorist is well served with straight forward access to the A23, which links to the M25 for routes into London or South towards Gatwick Airport and the South Coast. Unfurnished. Available now. Would suit either professional or retired couple.
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While it may not be difficult to buy replacement parts for Mitsubishi vehicles, these days the necessity for nothing but the highest quality are required to fix your car or truck. Mitsubishi automobile owners have become used to a certain level of a variety of features and options when driving their Lancer around town. Make no mistake, you bought your Lancer because you understood you would be getting Japanese engineering and youthfulness both rolled up into one vehicle. The vehicle in your driveway is head and shoulders above the rest when it comes to all the vehicles these days.
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Event Schedule
Our schedule can be impacted by a number of factors, not least being the availability of our guest speakers. As such the final schedule is not confirmed until a few days before the event.
That said, we do understand that you want to plan your weekend, so here is a rough outline to help you book trains, hotels, and so on.
Thursday 12th October
Liar Liar Pants on Fire
QED Fringe FREE TO ATTEND. Is it possible to spot lies? Using the latest research from the behavioural and psychological sciences, Dr Mike Drayton explores this question with video clips, examples from literature and audience participation. More information at gmss.uk.The King's Arms, Bloom Street, Manchester.
Note: this event does not take place at the QED venue.
Friday 13th October
SkeptiCamp Manchester
QED Fringe FREE TO ATTEND. No ticket required, just turn up! More details at skepticamp.co.uk.Park Suite, Fourth Floor
The QED Mixer 2017
QED Fringe FREE TO ATTEND. If you're new to QED or attending on your own, the Mixer is the perfect opportunity to get the QED party started early, meet new friends, and introduce yourself to a guest speaker or two. You'll also be able to pick up your name badge, saving valuable time on Saturday morning.Arts Brasserie and Bar
Saturday 14th October
Pick up your name badge and take your seats, ready for a prompt event start. Doors open 08:30.
Saturday Morning Session
Saturday Afternoon Session
The Gala Dinner
For Gala Dinner ticket holders only
Saturday Night
All QED ticket holders are welcome at our Saturday night, with entry included in your overall QED ticket price.
Sunday 15th October
Sunday Morning Session


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Amaze & Persuade – it's a bold statement but we believe it runs through everything we do. Take a look at our case studies to see our latest work.
As one of our long-standing clients, we continue to deliver impactful campaigns for Audley that always hit home. From extensive data planning to conceptual creative, we drive footfall to each luxury retirement village, as well as opening the door to successful property acquisition too.
From diamond rings to stunning watches, we're always on hand to help H. Samuel and Ernest Jones shoppers find that special something. With our sparkling strategic thinking, emotive messaging and impactful designs across POS, press, TV advertising, brochures and CRM, we help customers find the perfect gifts for any occasion.
We put on spectacular in store experiences with retailtainment at the heart of every one. Our shopper journeys engage at every touch-point, with our conceptual campaigns and creative product communications disrupting shoppers on the high street and enticing them in store to buy.
London Designer Outlet is an effortlessly stylish shopper destination, so we ensure our PR and event strategies are in line with consumer trends – generating lots of buzz, maximum footfall and brand awareness aplenty. With the ever-popular Peter Andre on board, we launched the LDO Play Park and drummed up bags of coverage in the first month alone.
We took a slice of business from this Spanish pizza company and launched them to a hungry UK market with a set of bespoke guidelines.
Think Disney and you think magic – so simply put, we bring that magic to life cross-category at key seasonal periods by tapping into Disney's unique power of storytelling. Our online and in-store activations are rooted with the emotion and creativity that make Disney films and channels more than fun, but lasting memories.
When it comes to a market as competitive as smartphones, it's simple: our communications need cut-through. So to re-charge Sony's position as a key player in this crowded arena, we power through multiple channels – including retail, partnerships, trade and experiential – with industry-leading creative, for an industry-leading brand.
With a refreshing range of brands across the Heineken portfolio, we brew up satisfying retail strategies, pour pints of our smart shopper insight into stores and serve up creative campaign ideas for disruptive POS – ensuring sales always bubble and never go flat.
Working with Wrigley gum brands, including Airwaves and Doublemint, gives us plenty to get our teeth into – from creating impactful in-store POS to analysing the full shopper journey for new opportunities to wow customers with fresh ideas.
We jumped at the chance to work with fun, nutritional snack brand, Bounce. We put a punch in the everyday routines of customers, and raise awareness around the unique benefits of their energy balls with dynamic digital, experiential and shopper activations – putting a spring in the sales as we go.
Disruptive, fun and inherently playful, our integrated Organic Naturally Different campaign has returned the organic category to growth – and picked up a few juicy awards along the way. With fresh thinking across press, social media and OOH advertising, it's only natural that sales continue to be on the rise.
We serve up a whole menu of shopper ideas across a tasty range of brands.
When it comes to expert skincare brands like Clarins, we're on-hand to apply expert advice. From immersive experiential events with strong digital and social presence, to collaborating with design & merchandising teams, we help Clarins engage with real women all looking for that next beauty must-have.
With the perfect blend of PR and shopper skill, we've helped spread awareness and grow media coverage for some of the UK's best-loved brands in the Dairy Crest portfolio. From celebrity endorsement, focussed trade campaigns and disruptive POS, we tempt shoppers with the tastiest messaging throughout the path to purchase.
We went back to class to develop a brand toolkit to get a plethora of bright-eyed freshers through the door come September. Plus, a new strategic positioning statement and visual identity for the Business School that made the grade – and then some.
With a healthy blend of PR, events, social media and influencer activity, our work for this fruity-favourite certainly packs a punch.
Our work with one of the nation's most loved chocolate brands takes us from strategic campaign planning and trade sell ins, to creative and production. We deliver equity-building brand activities, on pack promotions and shopper overlays for a variety of retailers.
Our team and dynamic culture has been at the heart of the business from the outset and makes Haygarth what it is. We're extremely proud to be listed in the Best Companies list for over 10 years, achieving a two star rating for 2017.
IMC European Awards 2016
Off the back of the 2x IPM GOLD wins for our Sony Everyday Extraordinary campaign, we represented the UK at the IMC European awards and won SILVER in the Innovative Idea category! We're so proud of the winning Sony Mobile campaign which revolutionised the smartphone demo – bringing together experiential with innovative technology to create a world-first consumer experience.
The Grocer Brand Experience Agency of the Year
(We have won 5 years in a row)
We have now won Brand Experience Agency of the Year for the fifth year running at The Grocer Marketing, Advertising & PR Awards 2015. Our ambition is to drive the brand experience industry as a whole and this award shows we're already doing it. But we couldn't have done it without our clients, so this is a big thank you for letting us create award-winning work this year!
Following the national and European award success of our Sony Mobile Everyday Extraordinary experiential campaign, we are incredibly proud to have been awarded a GOLD by the MAA WORLDWIDE GLOBES, recognising the very 'Best of the Best' in marketing campaigns executed globally.
(We have won 5 years in a row)
We brought home two Gold awards in the Best Experiential Activation and Best Consumer Product categories for our Clarins Urban Oasis campaign! Plus a Silver for Use of Innovation and Bronze for Creative Execution.
Clarins Urban Oasis toured the UK for 30 days, offering an immersive haven with a ground-breaking facial projection mapping experience that immersed thousands of consumers in the brand story and brought to life the powerful plant ingredients of the Clarins Multi-Active range.


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Ganze Unterkunft
2 Gäste
1 Schlafzimmer
1 Bett
- Free daily cleaning and towel change
- set safety box
- 5min walking distance from Nana and Asoke BTS to here.
- Homey studio with the kitchen.
- Gorgeous pool with nice night view and the gym.
- Free WIFI.
- Free shuttle to the main road on the request.
- Nice sofa, dining table and bed.
- We can keep your luggage to meet your schedule when checking in and out
- No pets
Der Wohnraum
-Homey and lovely 33 sqm condo.
-Cozy living room, clean bathroom, hygienic kitchen and balcony.
Zugang für Gäste
- 5mins to NANA/ASOKE BTS
- With your key card, you can access to 9F with the pool and gym
Interaktion mit Gästen
- Tell me anything that you want to know about the neighborhood and I can give you a hand to save your money and for a better holiday with you.
Weitere wichtige Infos
- We can keep your luggage to meet your schedule when checking in and out
No smoking in the room.
(please use the balcony).
Please turn off A/C, when you leave the room.
1 Nacht Mindestaufenthalt vom 26. September 2017 - 27. September 2017.
57 Bewertungen
Dieser Gastgeber hat 918 Bewertungen für andere Unterkünfte.Andere Bewertungen ansehen
Hi~ Everyone~


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|Publication number
|Publication type
|Application number
|PCT number
|Publication date
|Jun 10, 2008
|Filing date
|Aug 6, 2003
|Priority date
|Aug 24, 2002
|Fee status
|Also published as
|Publication number
|Ulrich Ensslin, Norbert Niemczyk, Hans-Gerd Seib
|Original Assignee
|Daimlerchrysler Ag
|Export Citation
|BiBTeX, EndNote, RefMan
|Patent Citations (10), Referenced by (1), Classifications (13), Legal Events (7)
|External Links: USPTO, USPTO Assignment, Espacenet
The invention relates to a method for temperature management and its use in a network.
Data buses for telecommunications and audio systems in means of transportation are often configured using ring topology. The data is transmitted here in a ring shape by means of each device which is connected to the data bus. Each device which is connected to the data bus has a receiver, a transmitter, and possibly an amplifier. Since the signal passes through each device, the failure of a single device can shut down the entire network (Grundlagen des Netzwerkbetriebs Fundamentals of Network Operation, 2nd edition, Microsoft Press 1997, pages 44, 45, 801, 808).
Failure of components which are used for transmitting data has particularly severe consequences in a network with ring topology. A faulty component causes the data communication of all the network users to fail.
Electronic components which are used for communication in networks with ring topology thus have to be protected particularly against damage or destruction.
Optoelectronic transmitting and receiving units in networks with ring topology are in use in industrial and medical applications and in means of transportation. A particularly significant role is played by optoelectronic transmitting and receiving units in particular in the multimedia networking of vehicles in conjunction with optical bus systems with ring topology.
Optoelectronic systems are used in multimedia networking technology MOST (Media Oriented System Transport). This technology was developed by various automobile manufacturers and suppliers on the basis of an optical bus system which was conceived specially for use in the infotainment area of a vehicle. Further information on the subject of MOST can be found, for example, in the periodical Electronik Electronics, 14/2000, page 54 et seq. and at http://www.mostnet.de.
Optoelectronic transmitter and receiver units are susceptible to damage or destruction because of overheating since optoelectronic units are limited to a maximum operating temperature for technical reasons. Particularly in conditions of use in which the ambient temperature of optoelectronic units rises to values above the permitted operating temperature owing to the environmental conditions, a total failure of the component, and thus of the network may occur.
When data bus systems are used in vehicles, that is to say control devices which are connected to a data bus via transmitting/receiving units are used, the ambient temperature may rise for various reasons. For example, as a result of the vehicle being used in regions with extreme temperatures such as Death Valley in the USA or the positioning of a control device connected to the data bus at a location in the vehicle where high temperatures are generated, such as for example the engine or exhaust system. In addition, a control device itself may generate a high power loss owing to its method of operation, such as is the case, for example, in a sound amplifier, which also causes the temperature of the control device to increase. If the temperature of the control device rises, the temperature of the corresponding transmitting/receiving unit also rises. When the maximum temperature of the transmitting/receiving unit is exceeded, said unit is irreversibly destroyed and the network communication collapses owing to the ring topology. As a result, the reliability of the network is determined by the transmitting/receiving unit.
WO 99/33294 discloses a method and a device for temperature management in cableless telecommunications networks. Here, when the temperature measured in a base station rises the transceiver in the base station is switched off by means of the corresponding mobile units. After the base station has cooled, the transceivers in the base station are switched on again by the mobile units. The method permits the operating temperature to be reduced when the base station overheats. The probability of failure of the base station is reduced.
DE 100 12 270 A1 discloses an optical header for components which are connected to an optical data bus with ring topology and which have a bypass which connects the input and output ports of the header. The optical header controls the connected components and is used to permit data to be exchanged between the data bus and the components which are connected to the header.
DE 197 26 763 A1 discloses a coupling arrangement for a master/slave bus system with ring topology which permits reaction-free coupling or decoupling of each slave user. In this context the rapid and direct actuation without user addresses is briefly interrupted in such a way that the control systems or computer systems which are connected via the bus system are not affected.
U.S. Pat. No. 6,014,304 discloses a networked control circuit for different functions in the vehicle. In this context, the temperature in the individual actuators is sensed and a control signal is generated if the temperature exceeds a threshold value.
The object of the present invention is to develop a method for a data bus system which increases the failsafety of a network with ring topology.
This object is achieved according to the invention by means of the features of claim 1. Accordingly, the temperature near to the transmitting/receiving unit of at least one control device is measured and as soon as the temperature at the transmitting/receiving unit of the control device exceeds a predefined critical temperature Tkrit, the transmitting/receiving unit is switched off and wakeup requests put onto the network via the control devices are blocked and the blocking of the wakeup requests is cancelled as soon as the temperature of the transmitting/receiving unit has dropped to a temperature below the predefined critical temperature Tkrit and below a predefined threshold value temperature Tth within a predefined time period, wherein the threshold value temperature Tth lies below the critical temperature Tkrit.
The transmitting/receiving units may be electronic, optoelectronic or else optical transmitting/receiving units. The transmitting/receiving units are often also referred to as bus drivers, transceivers or simply only network components.
The method has the advantage that no irreversible destruction of the transmitting/receiving units occurs since the transmitting/receiving units are switched off before the destruction by overheating.
In one development of the method according to the method, the control devices which are not affected by the overheating are informed so that they can initiate corresponding safety-related or preventative processes before the network is switched off.
Ideally, when there is a risk of overheating of the control device the generation of heat in the control device is minimized by maintaining only the device functions which are necessary for further monitoring. These are the wakeup standby mode of the control device and the measurement of the temperature of the transmitting/receiving unit of the control device. This is carried out by a quiescent current supply to the corresponding components.
In order to avoid further generation of heat it is tested whether the activation of the automatic air conditioning system or of a blower can reduce the temperature at the respective location in the vehicle. In addition, heat protection means such as sun visors or heat reflectors can be used.
The preventative safety measures include in particular reducing or switching off the vehicle's own heat sources: for example engine control devices can ensure that the engine can only continue to operate at low rotational speeds in order to avoid heat being generated. Control devices with a high power loss are switched off.
Furthermore, the overheating data, that is to say the control device and temperature, can be transmitted to an external control center for data collection. As a result, the corresponding control device and its environment can be examined for possible errors when the vehicle visits the workshop.
Since the time of the functional failure of the network is limited to a minimum time period, the failure of the network can be made reversible. By optimizing the predefined time period it is possible to keep the failure period of the network to a minimum.
The method is ideally suited for use in data bus systems in means of transportation. In the data bus system, the sensor is a temperature sensor which is positioned near to the transmitting/receiving unit. In addition, wakeup means for the data bus and transmitting/receiving unit switch-off means are present. In addition, a means is provided which interacts with the wakeup means and the transmitting/receiving unit switch-off means and the digital temperature signal in order to switch off the transmitting/receiving unit when a predefined critical temperature Tkrit is exceeded and to block the wakeup means.
The positioning of the temperature sensor near to the transmitting/receiving unit permits optimum temperature control of the transmitting/receiving units.
The interaction of the wakeup means, of the switch-off means and of the digital temperature signals is ideally carried out by using a means which is embodied by means of software or hardware. This direct interaction using a means permits optimum implementation of the method according to the invention.
There are various possible ways of advantageously configuring and developing the teaching of the present invention. In this respect, reference is made on the one hand to the subordinate claims and on the other hand to the subsequent explanation of an embodiment. The advantageous refinements, which result from any desired combination of the subclaims, are also to be included. An embodiment of the method according to the invention and a corresponding device are illustrated in the drawing, in which, in each case in a schematic view,
The method according to the invention for temperature management is embodied using the multimedia network technology MOST, that is to say as an optimum ring bus system 1 for infotainment applications in a vehicle. The control devices 2 exchange data via the bus system 1 by means of transmitting/receiving units 5. The temperature is measured at the transmitting/receiving units 5. As soon as the temperature at a transmitting/receiving unit 5 of a control device 2 exceeds a predefined critical temperature, the transmitting/receiving unit 5 is switched off and the wakeup requests put onto the bus system 1 by the further control devices 2 are blocked.
A plurality of control devices 2, which exchange data via the network 1, are connected to the network 1 in
The conversion of the electrical signals into optical signals and vice versa is carried out by means of optoelectronic or fiber-optical transmitting/receiving units 5, referred to as FOTs (fiber optical transceivers). Each control unit 2 is connected via a standardized plug to the transmission medium, the optical bus system 1.
The bus communication is performed by the MOST transceiver composed of the microcontroller 9 and of the optoelectronic transmitting/receiving unit 5. The MOST transceiver makes available the basic functions of the network management at the lower level. These functions include, inter alia, the mechanisms for transporting the individual services. Above these there is the level of "NetServices" which run on the microcontroller, said level already counting as part of the network. The "NetServices" are composed of the mechanisms and routines for operating and managing the network.
In addition, the temperature control unit contained in the control device 2 is shown in
The temperature sensor 6 is capable of measuring the temperature with a precision of �1 degree Kelvin. The temperature measurement is carried out in the direct vicinity of the optoelectronic transmitting/receiving unit 5. A distance of approximately 10 mm is usually selected between the optoelectronic transmitting/receiving unit 5 to be measured and the temperature sensor 6. Alternatively, the temperature sensor 6 can also be mounted at another position in the device 2 provided the temperature values are correlated between the optoelectronic transmitting/receiving unit 5 and the actual measuring point.
The temperature control unit is equipped with a program which is implemented by means of software and which runs on the microcontroller 8, in order to carry out the method steps according to the invention.
When a maximum temperature of the optoelectronic transmitting/receiving unit 5 is exceeded, said unit is irreversibly destroyed and the network communication collapses owing to the ring topology of the network 1. In order to avoid this, the temperature control unit is integrated in each control device 2. This temperature control unit is capable of detecting a rise in temperature and taking corresponding protective measures.
The temperature in the optoelectronic transmitting/receiving unit 5 is continuously measured by means of the temperature sensor 6 and processed by the microcontroller 8.
If the temperature rises above a value Tinf, all the further users 2 of the ring 1 are informed about the rise in temperature and the resulting possible overheating by the temperature control unit by means of the "NetServices". In this context the variable "temperature" is set to the value "warning".
For the provision of information by the temperature control unit it is irrelevant whether the rise in temperature takes place during the ongoing operation or directly after the system starts. The provision of information is carried out by means of the "NetServices" mentioned above.
With this provision of information further preventative protective measures are initiated. Thus, for example the control device 2, which forms the interface with the mobile telephone, automatically activates the mailbox of the mobile telephone in the provider. This is necessary since when overheating has occurred this switching over can no longer take place and in addition calls can no longer be received.
The Tele-Aid service, which requests help via an external control center in an emergency using SMS (Short Message Services) messages is also switched to the minimum mode, which is defined by the fact that the network functionality is no longer required. The control device 2 therefore no longer needs to access the bus system 1.
When the network users 2 are provided with information by the temperature control unit, information is also provided to the driver. This is done by a Man/Machine Interface control device 2 (MMI controller) outputting a corresponding item of information to the driver as soon as the variable "temperature" is set to the value "warning" or the message about the switching off of the optical data bus 1 is output. In particular, the driver must use information that the infotainment will possibly be switched off owing to overheating, and that for example his mobile telephone has been switched over to the mailbox.
If the temperature in the optoelectronic transmitting/receiving unit 5 drops again to a temperature below a threshold value Tth, the rise in temperature has been overcome. The temperature control unit informs all the users of the ring 1 by means of the "NetServices" by the temperature control unit setting the variable "temperature" to the value "normal". In
In contrast, if the temperature in the optoelectronic transmitting/receiving unit 5 rises further and exceeds a temperature threshold "Tkrit" which is critical for the operating state of the optoelectronic transmitting/receiving unit 5, the voltage supply of the optoelectronic transmitting/receiving unit is switched off and the wakeup standby mode for the network 1 is blocked. Before the overheated optoelectronic transmitting/receiving unit 5 is switched off, the temperature control unit informs the further network users 2 of the imminent switching off of the optical bus system 1. The further network users 2 then switch into a standby mode. The standby mode is characterized by the fact that sufficient quiescent current for the standby function is made available to the control devices 2.
For example, in the case of a remote-controlled radio-operated lock system for a vehicle, the control device 2 with the radio sensor is in the standby mode when the vehicle is switched off. This means that the radio sensor receives sufficient quiescent current for it to be able to sense a radio signal of the remote control system when it occurs. In response, the control device 2 wakes the bus 1. The control devices 2 are also in the standby mode with respect to signals from the bus system 1.
A further network user 2 can also only switch off the optoelectronic transmitting/receiving unit 5 if it can also function without bus communication.
In addition, a fault code DTC (Detected Trouble Code) is stored for later diagnostic purposes. In the exemplary embodiment, after the network users 2 have been informed the fault code together with the environment data "kilometer reading" is stored in the diagnostic memory of a control device 2 specially provided for that purpose, in the following format: Dd dd ss hh yy km km km (Dd dd="fault code for critical transmitting/receiving unit temperature", ss=status "active/passive", hh="fault counter", yy="MainFBlockID", km km km="kilometer reading with hi-mid-low-byte"). This fault code can only be read out and deleted by a special diagnostic program.
In order to cool the overheated optoelectronic transmitting/receiving unit 5, the control device 2 is placed in an energy saving mode in which applications which are not required are powered down, the optoelectronic transmitting/receiving unit 5 is switched off and the temperature control unit remains activated. With this measure the generation of heat is reduced to a minimum. The energy saving mode of a control device 2 thus corresponds to the standby mode of a control device 2 with the difference that in the energy saving mode the temperature control unit has to be additionally supplied with power. The consumption of power should also be as low as possible in the energy saving mode in order to avoid unnecessarily loading the battery of the vehicle. As a result, the energy saving mode generally exceeds the quiescent current requirement of the standby mode.
In this energy saving mode, the temperature control unit blocks the wakeup line of the optical data bus 1 in order to prevent the wakeup standby mode of the network 1. In the exemplary embodiment, the wakeup line of the optical data bus 1 is implemented as an electric line. The blocking is carried out by connecting the electric line to ground. As a result, no further control device 2 can transmit a message via the ring 1.
The energy saving mode is maintained only over a maximum predefined time period in order to avoid emptying the battery of the vehicle. In MOST systems in vehicles with average batteries the time period is usually restricted to a maximum of 30 minutes.
Provided that the overheated optoelectronic transmitting/receiving unit 5 cools to a temperature below the threshold value Tth in this predefined time period, the wakeup standby mode of the network 1 is enabled again by disconnecting the wakeup line from ground. Wakeup requests from the network users 2 can thus power up the ring 1 into the normal state.
If the overheated optoelectronic transmitting/receiving unit 5 of the device 2 does not cool in the predefined period of time of 30 minutes to a temperature below the threshold value Tth, the energy saving mode is exceeded. The control device 2 is switched off into the standby mode. When switching off takes place, the connection of the wakeup line to ground is also cancelled. The device 2 can draw its quiescent current. The temperature monitoring unit does not need any current any more.
In this state, the MOST network 1 can be activated again by the further network users 2 by means of wakeup requests. If the overheated optoelectronic transmitting/receiving unit 5 of the control device 2 has not cooled by the next wakeup process by a network user 2, the respective device 2 would be switched into the energy saving mode again by means of the method according to the invention.
Usually, the following values are used in MOST systems in vehicles for the defined temperature sections
Tth+75� C.
Tinf+80� C.
Tkrit+85� C.
As already stated, the temperature values are determined by the operating temperature properties of the transmitting/receiving units 5 which are used in the network with ring topology 1. In the exemplary embodiment here, this corresponds to the temperature properties of the optoelectronic transmitting/receiving unit 5.
However, in the exemplary embodiment the control device 2 could also be any control device such as is used as a sensor, actuator or for controlling, in means of transportation, industrial applications or medicine.
In the exemplary embodiment, the network 1 is a MOST network. However, the method can also be used in other bus systems such as CAN, D2B, FlexRay etc.
The transmitting/receiving unit 5 does not need to have an optical component. The method and the device can also be applied to an electrical transmitting/receiving unit or to an optical transmitting/receiving unit.
The temperature control unit is implemented in the control device for technical reasons associated with cost. However, it is also possible to mount it as an independent unit outside the control device depending on the respective application. Only the positioning of the temperature sensor 6 is a restriction here.
|Cited Patent
|Filing date
|Publication date
|Mar 31, 1997
|Jan 11, 2000
|Stmicroelectronics Gmbh
|Method of and apparatus for controlling a plurality of mutually communicating actuators
|Dec 23, 1998
|Apr 17, 2001
|Tocom, Inc.
|Environmental condition control and energy management system and method
|Nov 3, 1997
|Aug 20, 2002
|3Com Corporation
|Push button shutdown and reset of embedded systems
|May 24, 2000
|Nov 19, 2002
|General Motors Corporation
|In-vehicle network management using virtual networks
|Apr 17, 2001
|Jul 8, 2003
|John Friede
|Wakeup and safety circuits
|Jun 26, 2001
|Nov 22, 2001
|Yazaki Corporation
|Optical ring network, optical connector, and hybrid connector
|Mar 14, 2000
|Sep 27, 2001
|Daimler Chrysler Ag
|Optical header for optical data bus system, has optical gate electronically switched to state of minimum insertion loss during partial failure of electronic component
|Jun 24, 1997
|Jan 7, 1999
|Phoenix Contact Gmbh & Co
|Kopplungsanordnung f�r ein Master-Slave-Bussystem
|Nov 29, 1988
|Jun 7, 1989
|Smart House L.P.
|Communication and energy control system for houses
|Dec 15, 1998
|Jul 1, 1999
|Telefonaktiebolaget Lm Ericsson (Publ)
|Temperature control safety mechanism for radio base stations
|Citing Patent
|Filing date
|Publication date
|Dec 24, 2003
|Dec 1, 2005
|Yuji Mizuguchi
|Data transmission device, data transmission system, and method
|U.S. Classification
|700/299, 702/132, 701/36
|International Classification
|Cooperative Classification
|European Classification
|Sep 12, 2005
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Clearwel eDiscovery Software Components - On-Premise licenseItem#: 13692497 | Model#: 15168-M1
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Force - Wogma Readers Reviews
Force is a perfect masala film, which also means, it is perfectly predictable. And yet, Force keeps you engaged. It has everything in the right proportion - romance, action, drama. But it doesn't have that one overwhelming factor which can make me recommend it to you without any reservations. I have to add caveats like, if you are into hard-core action, if you like borderline genuine romance, if you don't mind the two interrupting each other, then watch it for sure.
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Advanced Enrollment Deposit
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1991 Volkswagen Vanagon Paper Repair ManualReview Fitment Notes to Ensure Proper Fit
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RGUHS Time Table 2017 rguhs.ac.in mbbs bsc nursing bds pharmacy bams schedule download pdf 1st 2nd 3rd 4th final year exam date rguhs home page
RGUHS Time Table 2017 has been published for UG and PG medical courses on the official web site www.rguhs.ac.in. Students those who are doing degree and diploma programmes can visit the RGUHS home page to download Rajiv Gandhi university of health sciences examination timetable 2017 online. The RGUHS university is going to conduct semester exams on April & May 2017 for fist year, second, third, fourth and final year.
It has released RGUHS exam schedule or date sheet on the internet as pdf file. students can get it by their degree courses like MBBS BDS BAMS BPT MS MD MPT M.Sc BSc Nursing Physiotherapy BHMS BNYS. Students can visit www.rguhsqp.com site to get examination application form, centres and other information. To get latest updates, revised timetable and notification visit rguhs home page.
Rajiv Gandhi University of Health Sciences (RGUHS) Exam Time Table 2017:
The Rajiv Gandhi University of Health Sciences which commonly known as RGUHS University located in Jayanagar, Bengaluru, Karnataka State is affiliating with many other colleges. The RGUHS is offering courses in various departments like Medical, Dental, Ayurveda, Unani, Naturopathy & Yogic Sciences, Homeopathy, Pharmacy, Nursing, Physiotherapy, and Allied Health Sciences. Most of the students prefer to take Nursing, MBBS, and Pharmacy courses in admission which is conducted every year.
RESCHEDULING OF EXAMS - All examinations scheduled on April 2017 are rescheduled to be held from April, 2017, PG Medical MD and MS Exams are rescheduled to be held from May 2016 and PG MDS Exams are rescheduled to be held from July 2017 onwards
Note: Examinations to be held on dates other than the above mentioned remains unchanged.
Click here to check latest notification.
The RGUHS started the admission process for the following UG courses MBBS and BDS, Ayurveda, Homoeopathy, Naturopathy & Yogic Sciences, Unani, B.Sc (Nursing), PB BSc (Nursing), Para Medical Courses, Lateral Entry - Para Medical, B, Pharm, II B Pharm, Pharm D, and Pharm D Post Baccalaureate and PG Courses Ayurveda, Homoeopathy, Nursing, MPT, M Pharm, Medical and Dental, Medical - Super Speciality, Fellowship Medical 2017-June, and Fellowship Dental 2017-June. Many students showed interest on getting admission in offline and online mode registration / application form submission.
Now all the students are looking for the RGUHS Exam Time Table 2017 which has been uploaded on the official site http://www.rguhs.ac.in/. All the 1st year, 2nd year, 3rd year, 4th year an final year students can refer the below given table to get the latest / revised exam time table / date sheets 2017 online.
Download Link
|List of Observers for Theory Examination of Nursing AYUSH AHA MPT Courses - April/May 2017
|Circular regarding Guidelines for all UG / PG Theory Examination Centers April / May 2017
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|Pharmacotherapeutics 1 Question Bank of May 2017
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|Revised Time Table for Under Graduate Allied Sciences Examination March / April - 2017
|Revised Notification and Time Table for AYUSH (PG) Examination during April/May 2017
|Revised Time Table for BPT (Physiotherapy) Courses Examination March / April - 2017
|Revised Time Table for conduct of B.Sc Nursing Examination March / April - 2017
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|Notification and Time Table for conduct of M.Sc Nursing Theory Examination during April 2017
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As of now the students would be enough study exam holidays as given in the calendar 2017, everyone should schedule their study plan and prepare well by referring the syllabus and previous year question paper. Once you know the exam question pattern and the syllabus and dates, it would be easy for you to clear the subjects with good marks. If there is any changes in the RGUH Exams are postponed, then the new exam dates will be announced at the notification section below.
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RGUHS Online Payment Gateway
Click Here to Pay Student Fee
Click Here to Pay College Fee-Affiliation/Admission/Helinet
Click Here to Pay College Fee-Examination


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Matteo Ferrari eBooks
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Risk Perception, Culture, and Legal Change: A Comparative Study on Food Safety in the Wake of the Mad Cow Crisis
Matteo Ferrari
Routledge, March 2016
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