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Reviewed By Gregory B (WHITEVILLE, NC) Reviewed for a 2016 Dodge Ram —9/16/2017 7:09 AM
Being 64 years old I could not get into the truck bed with out this step easy to install, sturdy, and easy to use makes this product the best addition yet
Reviewed By Timothy S (West Fargo, ND) Reviewed for a 2015 GMC Sierra —4/12/2017 5:55 AM
The step works will and looks good, however installation was not as advertised. The brackets did not fit good and when tightened up everything twisted and the stop bold barely hit the from. Also it rubs along the spring.
Know before you buy! Read customer reviews about Bestop Truck Bed Accessories or ask our Product Experts.
At SEMA 2012, AutoAnything met with Bestop's Marketing Manager, Megan Thompson, for a closer look at their thrilling, new products.

subset: commoncrawl


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Question: A truck driving on a level highway is acted on
A truck driving on a level highway is acted on by the following forces: a downward gravitational force of 52 kN (kilonewtons); an upward contact force due to the road of 52 kN; another contact force due to the road of 7 kN, directed east; and a drag force due to air resistance of 5 kN, directed west. What is the net force acting on the truck?
Relevant QuestionsWhile trying to decide where to hang a framed picture, you press it against the wall to keep it from falling. The picture weighs 5.0 N and you press against the frame with a force of 6.0 N at an angle of 40° from the ...You are pulling a suitcase through the airport at a constant speed. The handle of the suitcase makes an angle of 60° with respect to the horizontal direction. If you pull with a force of 5.0 N parallel to the handle, what ...A man lifts a 2.0-kg stone vertically with his hand at a constant upward velocity of 1.5 m/s. What is the magnitude of the total force of the man's hand on the stone? A woman who weighs 600 N sits on a chair with her feet on the floor and her arms resting on the chair's armrests. The chair weighs 100 N. Each armrest exerts an upward force of 25 N on her arms. The seat of the chair exerts ...An astronaut stands at a position on the Moon such that Earth is directly over head and releases a Moon rock that was in her hand. (a) Which way will it fall? (b) What is the gravitational force exerted by the Moon on a ...
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(2008 status — Dating Mike for three weeks, the smittenest of smitten)
Do you want to have a boyfriend this summer?
Yes. Which is good, because I already do. Allegedly, he'll still be here in the fall.
(He was. He still is.)
Who was the last person you fell asleep with?
Mike – we had a sleepover. Again. We do that a lot.
Are you a morning person or a night person?
A night person, fo sho.
(So, when we started dating, Mike was a crazy morning person. If he woke up at 5 a.m. to pee, he'd just stay up, and start working, or playing computer games or something. And he always fell asleep before I did. Always. I'm not sure when that stopped, but now, every night, I fall asleep while he watches old Star Trek episodes on the iPad, and he is the grumpiest of grumpy-pants in the morning. I think he's worse than me. My mother and former roommates can verify that that is super-grumpy.)
What would you do if you opened up your front door to a dead person?
Like, a zombie? Or a corpse? Because my reactions to either would be drastically different…
(Corpse? Quick assessment. 1) Do we need to hide the body? Or are we in the clear? 2) Are we being framed? 3) Where is their wallet? Ok, call the police OR find an old rug we don't care about. Zombies? 1) Hope for slow-moving Shaun of the Dead zombies, and not Zombieland zombies. 2) Get the pointy shovel from the garage and Mike's golf clubs. 3) Destroy zombies, like this:
Who's bed did you last sleep in?
Mike's – hence the aforementioned sleepover.
(Mike & I started dating right before summer — so after a few weeks, I sort of moved in. He had central air, and my house was like an oven. Also, to say his house needed a woman's touch would be an understatement.)
Where is the next place you will travel to?
Um…possibly Gettysburg on Father's Day. OC in August for sure.
(Family vacation update: 15 days!! Get your game faces on, family. Cooooofeeeeee Table!)
Have you ever worn the opposite sex's underwear?
I live in wifebeaters. Does that count?
Have you cried today at all?
No, but I was cranky pants this morning when I had to get up for work.
What were you doing at 8:00 this morning?
Still sleeping. Oops!
Do you say sexy a lot?
I tend to refer to things and their lack of sexiness.
(For example, things that are not sexy: the words "panties" and "coochy," getting in or out of a hammock, going out to lunch and sitting outside — and then realizing you forgot to put on deodorant, or seeing your boss without his shirt on.)
When was the last time you had a sleepover?
Last night!
Do you want to get married & have children one day?
Yes, and yes.
(Speaking of babies — in addition to all the appointments and tests we're paying for, and which don't count towards our deductible, I got a speeding ticket on my way to the doctor the other day. I'm adding it to the baby's tab.)
Favorite colors?
What was the last thing you bought?
Food? Clothes? I can't remember.
Where do you keep your money?
In a box in the toilet tank, just like in Pretty Woman.
What is the weather like today?
Hot, but not like balls hot.
(Today? It really is balls hot out there. Someone needs to punch Mother Nature in the face.)
Where are your parents?
They better be working. One day they're going to have grandkids to buy things for.
What do you want for Christmas?
A puppy.
(I got one!)
Do you like to eat ice-cream?
Um, Yes. I would eat ice cream every day.
(Especially on days as hot as this.)
When do you go to sleep?
Bedtime! Burn!
Who was the last person of the opposite sex that you talked to?
Mark, in my office. I offered to help him change the water bottle thingy, but then I said I was just being polite, and I didn't really want to.
Do you have empty bottles of alcohol hidden somewhere?
I wouldn't call strewn about my cubicle floor hidden, necessarily.
Are you over the age of 25?
I am. I am also over the age of 26.
(… and now I'm officially over the age of 30. Which means I'm old, but my mom is even older.)
Are you typically a jealous person?
No. OK, Yes. I was lying before.
Own bright colored underwear?
Yes. Although, it's also edible.
What was the best movie you have seen in the past two weeks?
Sex and the City. Shoes?! Nudity?! Marital drama?! Yes, please.
(I'm finally going to see Harry Potter today!! And I already know it will be the best movie I've seen in the past two weeks. Also, since the last time I went to see Harry Potter.)
Do you have strange dreams?
What are you listening to?
People talking about pizza. I want to run over there and steal it from them, then run down the stairs laughing maniacally and then eat the whole thing in my car.
(The hum of the air conditioning. Also, now I want a pizza.)
Do you currently miss someone?
I miss your dad a little.
Three feelings at the moment?
Smitten, smietest, smytst.
Do you like your mom?
I like YOUR mom.
(I do like my mom, in case you were really wondering.)
Name someone with the same b-day as you?
LL Cool J. True story. Look it up.
What are your plans for tonight?
Gym, groceries, cleaning and organizing. It's going to be a very domestic night.
(Harry Potter! Harry Potter! Harry Potter!)
If you could move somewhere else, would you?
Can I take everyone with me? Well, not everyone, but the people I like? Then yes.
(I'm not allowed to move more than 30 miles away from my mother. It sounds like a joke, right? because she loves me so much? She's serious though. She told Mike that about 30 seconds after he proposed.)
Do you know if anyone likes you?
Bubz does. He told me so 158 times yesterday.
(He liked it so much, he put a ring on it, like seven months later.)


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Villa / house Rai
Please tell you have seen the ad in Rooms.bg
Villa "Paradise" is located 300 meters from the thermal pools and shops in the village Shipkovo. Shipkovo Village is located at the foot of the Troyan Balkan, 20 km from Troyan along the road to Ribaritsa. The village combines mountain air with the hot mineral springs and the great Balkan mentality. The freshness and ecologically clean nature, the unique combination of ancient beech forests and other coniferous trees, clear mountain streams, clean air, wonderful and unique rock formations and caves and healing mineral springs transform the village Shipkovo awesome and unique, more popular and busy place .
Has four comfortable and well appointed rooms. All are equipped with cable TV and refrigerator. Each room has its own bathroom. The villa has a maximum capacity of 14 seats.
The hosts offer a large garden with gazebos and barbecue and large terrace with sun loungers and swing for small children. Are provided and parking your car.
Business facilities
Prices per person
|Room Type
|from May 01
to Sep 30
|from Oct 01
to Apr 30
|Double room
|24.00 levs
|40.00 levs
|Apartment 3 pax
|36.00 levs
|60.00 levs
|130.00 levs
|200.00 levs


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One-Bedroom Apartment for 4 persons with balcony– Ćirila i Metoda38 Street
Prices are per apartment
Included in apartment price 10 % VAT, city tax (Croatia).
The apartment is fully equipped and modernly furnished, fully air-conditioned with balcony. It is located in the city center, Ćirila i Metoda Street, 150m away from Marmontova Street, the main promenade of Split, few min walk from Diocletian palace, Riva and all main traffic checkpoint (city port, train/bus).
There is public parking in front of the apartment.
Apartment is equipped with 1 double and 1 extendable sofa bed in the dining room, LCD cable TV andfree Wi-FiInternet access. A fully equipped kitchen and a private bathroom are also provided. Transfers and excursions possible.
Apartment Facilities: Air Conditioning, Heating, Desk, Seating Area, Private Entrance, Parquet Floor, Sofa, Bathroom, Shower, Hairdryer, Toilet, Washing Machine,Towel Heater, Radio/AlarmClock, CD Player, LCD Cable TV, Free Wi-Fi, Refrigerator, Kitchen, Dining Area, Kitchenware,Oven, Dishwasher, Oven, Balcony
Apartment Size: 42 square meters
Bed Size (s): 1 double bed and 1 extendable sofa bed
Feel yourself like home, but look after the place. Everything is very nice and clean so lets keep it that way so you can have a nice stay like everyone before and after you. I'm at you disposal with cellphone or e-mail anytime. See you in Split soon! Thanks!
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as You can see my name is Vele. I live in Split. I love to travel, discover new places, meet interesting people. I love Dalmatian food that is far known brand in Split. If You want to know anything about my apartment that is not listed in description, please don't hesitate to contact me. See You in Split!!


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We welcome you to our church where Christ is lifted up above all others. We are a diverse group of people from all races and cultures gathered together in one place to learn biblical principles, find lasting friendships, encourage one another in the faith and more importantly, love one another. In short, a place to belong. The vision of Highest Praise Family Church is to present a clear message of the Gospel to all who are seeking the truth that is found in Jesus Christ.
Life can present you with some pretty substantial problems at times, but God is able to help us resolve them and we will join together with you in prayer for help in times of trouble. If you have ever said this about going to church, "I am not perfect",or "I have to get my act together first". I have great news for you, Jesus accepts you just the way you are. His loving, continual working in your life will help you take care of all those issues you might be concerned about.
We are a come as you are church , with contemporary worship music. Please join us Sunday as we gather together to worship Jesus Christ, the one who gave His life, so that we might live ours in the abundance of His grace. Your visit with us may very well be the best 90 minutes of your day.
Highest Praise Family church is telling the good news of the Gospel to all residents of New Port Richey, Trinity, Odessa, Port Richey, North Pinellas County and beyond.


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Liberia will host the pilot program of an agreement that allows autopsies to be conducted at hospitals belonging to the Caja Costarricense de Seguro Social.
Until now all autopsies were done at the Morgue Judicial at San Joaquín de Flores, Heredia. That meant that bodies from all over the country are taken there and that relatives have to retrieve the body there after the autopsy.
The agreement was signed by Luis Paulino Mora Mora, president of the Corte Suprema de Justicia and Ileana Balmaceda Arias, executive president of the Caja, Friday. Hospital Enrique Baltodano Briceño will become a location for the Sección de Patología Forense del Poder Judicial


text:
Your risks are unique. Sometimes you need an innovative solution, not a conventional risk transfer product.
At Swiss Re Corporate Solutions, we understand that the traditional market doesn't always meet your needs. That's why we use our risk capital to create smart, creative solutions to the most challenging risks around.
Our team of experts will work with you to create innovative risk-transfer structures for difficult to hedge risks. No matter your industry, geography or level of complexity, we're committed to protecting your business.
You have a problem, let's find a solution. We're smarter together.
Innovative Risk Solutions - Our value proposition (PDF, 303 KB)
Contact us to learn more.
The annual Airmic conference from 6-8 June provided a vibrant platform to highlight our primary lead capabilities, commitment to the UK regional market and expanding portfolio of commercial insurance offerings.Learn more
The Africa Energy Forum (AEF) is the global investment meeting for Africa's power, energy & infrastructure sectors. We are sponsoring and speaking at the event this year to highlight risk transfer possibilities for the continent's growing energy industry.Learn more
When a natural disaster strikes, there is a direct correlation between the conditions experienced locally during the event and the losses suffered on the ground. Parametric insurance products settle on the intensity of the experienced event and are linked to reputable, objective third-party sources, which are used to determine an insurance payout. They are designed to provide catastrophe coverage and complement, but not replace, traditional insurance coverage. Using this structure, parametric insurance payouts are quickly determined, easily measured, and effectively eliminate loss adjustment hasslesLearn more
Business interruption (BI) is widely feared in the corporate world. It also comes in many forms, such as cyber-attack, terrorism or natural disaster. Furthermore, the BI risk landscape is always changing in line with the broader operating environment.Learn more
Find out how we can make the world more resilient
Learn how we help protect our clients around the globe
Find out what we've been up to lately


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- Grant Access
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ifuonlyknew's Journal
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Created on 2009-05-04 13:12:16 (#272831), last updated 2011-06-16 (327 weeks ago)
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|Aug 27
|Massachusetts, United States of America
I'm finally getting to a point in my life where I feel like things are coming together. I've gotten a grasp on who I am and for now, how I want to live my life. I'm jobified and apartmentified. I've got family, friends, and lovers. Life is good.
angel, anime, art, bdsm, bisexuality, blue seed, books, boys, buffy the vampire slayer, candles, chobits, clay, comics, crafts, creativity, drawing, fimo, friends, girls, goths, hugging, inspiration, kissing, knitting, lovers, magick, movies, najica blitz tactics, paganism, painting, peace, people, piercings, poetry, polyamoury, reading, scrapbooking, sewing, sex, sex and the city, strangers in paradise, sushi, tatoos, the moon, the stars, the sun, vegetarians, writing
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Business Information and Business News - Forbes.com [ http://www.forbes.com ]
PR: 8Forbes.com a leading Internet media company, is among the most trusted resources for the world's business and investment leaders, providing them the uncompromising commentary, concise analysis, relevant tools and real-time reporting they need to succeed at work, profit from investing and have fun with the rewards of winning. Forbes.com includes real-time original reporting on business, technology, investing and lifestyle; stock and mutual fund quotes; comprehensive company profiles; a wide array of interactive tools, calculators and databases. [ Read more ]
Category: Business & Economy
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PR: 8Economist.com is the premier online source for the analysis of world business and current affairs, providing authoritative insight and opinion on international news, world politics, business, finance, science and technology, as well as overviews of cultural trends and regular industry, business and country special reports. Economist.com publishes all articles from The Economist print edition plus a searchable archive of all The Economist's articles back to June 1997. [ Read more ]
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PR: 7FOX Business Network - this exciting new venture at least 30 million homes nationwide, including the world's financial capital - New York - where you can find us on expanded basic cable. [ Read more ]
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Entertainment Weekly's EW.com | Entertainment News | TV News [ http://www.ew.com ]
PR: 7EW.com is the award-winning online extension of Entertainment Weekly magazine and the leading website about pop culture, presenting the Web's best daily news, reviews, commentary, and interactive features about every aspect of entertainment. Because they already bombarded with hundreds of entertainment options everyday, their goal is to provide information and recommendations that help you make the best choices and enhance your engagement with movies, DVDs,television, music, books, and the Internet. [ Read more ]
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Computer Arts - Home [ http://www.computerarts.co.uk ]
PR: 6The ultimate site for graphic designers with free downloads, in-depth tutorials, news, interviews, galleries, exclusive competitions, message board. Computer Arts aim to satisfy that passion by delivering some of the world's best-selling magazines serving the creative industry. Across all of our creative titles; Computer Arts, Computer Arts Projects, 3D World and MacFormat, you will find step-by-step tutorials, tonnes of tips and tricks for web design, typography, 3D, animation, motion graphics and multimedia. Together with reviews of the latest hardware and software releases, enhance your skills and knowledge with creative tips, technical advice and interviews from the leading experts in the global design world. [ Read more ]
Category: Arts & Humanities
Document Management [ http://www.cmswire.com/cms/document-management/ ]
PR: 6Document Management – Get in the loop. CMSWire.com has the latest document management news, software reviews and analysis. [ Read more ]
Category: Computers & Internet: Software
Houses For Sale In Gauteng [ http://www.property24.com ]
PR: 6Property24.com is South Africa's ultimate property website with the largest number of South African property listings – property for sale and to let. Get the latest property market news. [ Read more ]
Category: Blogs: Business
Entertainment weekly tv news [ http://insidetv.ew.com ]
PR: 6Entertainment weekly tv news: Star Alyssa Milano talks about her seductive new role. [ Read more ]
Category: Business & Economy: Security: CCTV
Election Observers [ http://polemika.com.ua ]
PR: 5Internet resource opening up the opportunity to be in the know of breaking news on election in Ukraine, breathtaking occurrences, the ultimate headlines, new photos and opinion on top stories. [ Read more ]
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Used Office Furniture Nashville, TN
5 results for Used Office Furniture in Nashville, TN
- Business To Business Xchange Woodycrest Ave & Foster Ave37210 Nashville, TN (615) 242-3636
... Merchandise Stores, Second Hand Goods, Second Hand, Used Office Equipment, Used Office Furniture
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- GLM Office Furniture 3 Cauley St37210 Nashville, TN (615) 943-1092Closed
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text:
Syria crisis: UK suspends non-lethal aid for rebels
The United Kingdom has joined the US in suspending aid for the opposition in northern Syria, the UK's minister for the Middle East says.
Hugh Robertson told the BBC that the move was in response to action overnight, when Islamist rebels seized bases belonging to the Western-backed Free Syrian Army (FSA).
Humanitarian assistance by the US and UK is not expected to be affected.
11 Dec 2013
- From the section Middle East


text:
Fraction of a Number
Learners explore how to multiply fractions using color tiles. They use the appropriate strategies for the multiplication of fractions. Students use 40 color tiles to practice multiplying fractions. They practice using various fractions to multiply.
6 Views 21 Downloads
Resource Details
Understand a Fraction as a Number on a Number Line
Piece by piece young scholars build a basic understanding of fractions in a Common Core-designed elementary math lesson. Through a series of hands-on activities and journaling exercises, and with the help of multiple online resources,...
3rd - 4th Math
Rational Number Project: Initial Fraction Ideas
Deepen the fractional number sense of young learners with this introductory lesson on equivalent fractions. After completing a short warm-up activity, children go on to work in pairs using fraction circles to complete a table of...
3rd - 6th Math CCSS: Adaptable
Initial Fraction Ideas Lesson 9 Overview
Visual models support young mathematicians with exploring equivalent fractions. Starting with a quick warm-up problem, children go on to work through a series of guiding practice problems before working with a partner identifying and...
3rd - 6th Math CCSS: Adaptable
Locating Fractions Greater than One on the Number Line
Supplement your lesson on improper fractions with this simple resource. Working on number lines labeled with whole numbers between 0 and 5, young mathematicians represent basic improper fractions with halves and thirds. The fractions...
3rd - 5th Math CCSS: Designed
From Ratio Tables to Double Number Line Diagrams
How much sugar is in one bottle? Pupils use double number line diagrams to determine the amount of sugar in a 1L bottle of cola. The teacher leads a discussion on ways that double number lines can be of assistance in solving a problem...
6th Math CCSS: Designed
Extend a Fraction Using a Number Line
Add depth to your class' understanding of fractions with video seven of this nine-part series. Building on prior experience representing fractions on number lines, young mathematicians learn to identify and extend patterns involving the...
5 mins 3rd - 5th Math CCSS: Designed
Start Your Free Trial
Save time and discover engaging curriculum for your classroom. Reviewed and rated by trusted, credentialed teachers.Try It Free


text:
Vipers will play during halftime in Storrs
BRATTLEBORO >> When the UConn women's basketball team begins its journey toward a fourth-straight National Championship today, 10 area girls will be at Gampel Pavilion in Storrs, Conn. to cheer the Huskies on.
And during halftime of the Robert Morris-Connecticut tournament showdown that will start at 11:03 a.m., those Vipers AAU seventh graders will take the court for a short game. The players include Audrey Martin, Natalie Hendricks, Julie Hendricks, Sarah Butterfield, Katrina Tao, Brenna Beebe, Delaney Wilcox, Angelina Nardilillo, Amelia Harrison, and Lily Giroux.
Coached by Tom Hendricks Jr., Jaida Henry and Amber Pillsbury, the Vipers will compete in five tournaments this season. The first of those is scheduled for April 2-3 in Barre, followed by tourneys in Putney, Castleton, Burlington, and Keene, N.H.
The 32-0 Huskies enter March Madness on a 69-game winning streak and have captured the last three titles. Senior Breanna Stewart is scoring a team-high 19.2 points per game for UConn, which has the top rated offense and defense in the country. And Robert Morris has 6-3 center Mikalah Mulrain, who has blocked 46 shots this season.
UConn, Baylor, South Carolina and Notre Dame are the four No. 1 seeds in the Division 1 bracket.
If you'd like to leave a comment (or a tip or a question) about this story with the editors, please email us. We also welcome letters to the editor for publication; you can do that by filling out our letters form and submitting it to the newsroom.


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Ad Number: 1031522 | Posted by Dustin Font | 8/13/2017 9:31:25 AM | It is currently Available
ForSale: Benelli super nova 12 g pump shotgu
Benelli super nova 12g pump shotgun with max four camo never had a issue looking to up grade great waterfowl gun and the season is just around the corner so shoot me a text or email Asking 600$
Price: $600Contact me: 5199180447 or use the form below
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A light, fresh and easily absorbed hand cream formulated with Sicilian lemon oil and prebiotic oligosaccharides to protect the hands and nails against bacteria while keeping hands hydrated and nourished.
Key ingredients:
- Oligosaccharides protect and soothe.
- Antileukine from ochroleuca seaweed helps reduce irritation.
- Omega 3 and glycerides from Arctic blackcurrant and shea butter nourish the skin and help repair dry, chapped hands.
- 10.2 oz.
- By REN.
- Item #687728
Citrus Aurantium Bergamia (Bergamot) Leaf Extract, Cetearyl Alcohol, Stearyl Heptanoate, Caprylic/Capric Triglyceride, Vitis Vinifera (Grape) Seed Oil, Simmondsia Chinensis (Jojoba) Seed Oil, Cetearyl Glucoside, Lauryl Laurate, Butyrospermum Parkii (Shea Butter), Glycine Soya (Soybean) Oil, Glycerin, Alpha-Glucan Oligosaccharide, Citrus Medica Limonum (Lemon) Peel Oil, Limonene, Citral, Linalool, Geraniol, Oryzanol, Ribes Nigrum (Black Currant) Seed Oil, Phenoxyethanol, Laminaria Ochroleuca Extract, Sodium Hydroxymethylglycinate, Carbomer, Citric Acid, Tocopherol.
Ingredients are subject to change at the manufacturer's discretion. For the most complete and up-to-date list of ingredients, refer to the product packaging.


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When I sent my sister an e-mail letting her know that Mary Oliver would be reading in Brookline, she sent me back a single word: YES. She then stole a friend's truck to drive 70 miles on a weeknight to join me in the Coolidge Corner theater in which every red velvet seat was filled, and people spilled out into the aisles.
The young woman who introduced Ms. Oliver in a manner that was both gushing with admiration and knowingly self-deprecating, described the poet as writing from a sincere and "humble" place, despite her extensive awards and accolades. I wish I could remember her words precisely, as they resonated with me even before I had her Mary Oliver speak. I had read some of her poems before but not to any great extend. That is about to change.
"Have you ever tried to enter the long black branches of other lives…?" she askes us, and "Listen, are you breathing just a little, and calling it a life?" These are among the many soul-stirring questions she poses to her readers. Her poems stem from a passionate, but as said "humble" devotion and involvement with nature. There is a tenderness as well as a fierceness to her writing, a simplicity as well as an insistent sincerity. She uncovers life's questions and answers in the woods and the nature around her. She also has a sweet sense of humor. She was a pleasure to listen to.
As we sat in the theater listening to Mary Oliver read poems from a smattering of the twenty-five or so books of poetry she's published, I was caught up in the reaction of the audience, the murmurs and sighs, the tiny groans of contentment. The woman sitting to my right, uttering a soft "wow" after a particularly moving phrase. There was a feeling that each poem literally struck a chord in each person in the room, sending out a ripple of sound and movement. I don't think I've ever witnessed that kind of audience reaction to a reader before. Laughter, yes, applause, certainly. But this kind of physical and unwittingly vocal response… it was a wonderful experience.
I haven't been to a poetry reading in a long time. I enjoy poetry but for some reason I think I would be more likely to go hear an unknown author than an unknown poet. Why is that? Maybe because I don't read that much poetry, maybe because of the extremely personal nature of poetry. The idea that for a moment, while listening to a poet read, you are sitting in the living room of their mind or heart. I guess for me I'd rather that living room be a familiar space. However, I am on a d-list or two for local poetry readings, which I always skim for readings such as this. Maybe in the new year I'll take the plunge and check out some new poets.


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Two other recent bits about Colin.Nov. 16th, 2010 10:34 am
I wrote that developmental update while I was at my faculty retreat last week. Since then, Colin has picked up two awesome new things I want to share:
- A while back he learned to sing "Goodnight Ladies." "Goodnight ladies, we're going to leave you now." Then he did a little experimentation with changing "ladies" into people's names: "Good night Mama, we're going to leave you now."
This weekend he started changing the lyrics entirely. Michael left the dinner table to go to the bathroom, and Colin broke into song: "Good night, Daddy, going to pee potty." And this morning, as Alex settled in to watch her video: "Good night, Alex, going to Liberty's Kids show."
- He's started carrying news. We went in to wake Alex up this morning, and he eagerly reported to her about his exciting new pajamas: "Alex! Colin dinosaurs on there!" Michael had a massive sneezing fit, and Colin came into the next room and told me excitedly, "Mama, Daddy sneezed! Daddy sneezed!"
This isn't flat-out funny like singing "Good night, Daddy, going to pee potty," but it's a big developmental leap because it shows that Colin is starting to understand that everyone doesn't know what he knows. That's the beginning of a theory of mind.


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Tuesday, October 2, 2012
Food Bank Benefit - Classical Piano Concert
Anacortes Adventist Fellowship welcomes Merry Maricich to our piano. She will be sharing lovely classical music Friday evening, October 12 at 7 p.m. Merry is a familiar face at the piano to many in Anacortes as she has been the pianist for St Marys Catholic Church and is currently the pianist at Sacred Heart Catholic Church in La Conner. Join us for a lovely relaxing end to the week, a good will offering will be taken to benefit area food banks.
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Stan Collymore on Everton & young players
Stan Collymore says Dominic Calvert-Lewin has "something special" and is set for a "long and successful" career with Everton and England.
Calvert-Lewin has enjoyed a stunning rise to prominence following his move to Goodison Park from Sheffield United one year ago.
The 20-year-old was promoted into Ronald Koeman's first-team within months of joining and started five Premier League matches last term.
And after a heady summer in which he struck the goal that won the World Cup for England's Under-20 team in Korea, Calvert-Lewin has returned to Goodison Park to become a pivotal figure under Koeman this term.
The youngster continued his high-achieving exploits in this current international break, scoring on his England Under-21 debut in Holland and then delivering a terrific cameo from the bench as Aidy Boothroyd's side beat Latvia on Tuesday night.
Collymore has closely monitored the progress of Calvert-Lewin and his fellow band of homegrown Everton stars.
And the former Nottingham Forest and Liverpool striker is enormously impressed by both Calvert-Lewin's talent and fearless outlook on his profession.
"There is undoubtedly something special about the fact he clearly wants to be in the first team," Collymore told evertonfc.com.
"It is not just about wanting to see young players come through, which we all like at our clubs. I want young players who are looking at the gaffer and saying, 'get me on, get me on' – and he seems that type of character.
"I was in the States recently talking to Patrick Vieira (currently managing New York City and formerly in charge of Manchester City's Academy), about Under-23s playing against Under-23s, in an Under-23s league – having the comfort blanket of being at a big club.
"When young players come out and say, 'give me the opportunity' – that is what I want to hear.
"In that respect, Dominic reminds me of Robbie Fowler – and Michael Owen, who also made his debut early."
Everton manager Koeman has demonstrated a real keenness to give opportunities to the Club's younger players.
Academy graduate Tom Davies had his breakthrough campaign on the Dutchman's watch last season, while Koeman has also invested enormous trust in youngsters Mason Holgate and Ademola Lookman at various junctures of his reign.
Lookman, Davies and Jonjoe Kenny all joined Calvert-Lewin on England Under-21 duty this week.
And Collymore insists Everton are fast becoming one of the most attractive destinations for the country's brightest young prospects.
"Everton is definitely a place you would want to go as a young player now," said Collymore, who admits to having a "soft spot" for the Blues, despite his two years playing across Stanley Park.
"I think there are a lot of similarities between Everton and Spurs. Both clubs buy diligently, but they do not burst open the transfer kitty when they can give a young player an opportunity.
"And an opportunity means six to 10 games, it doesn't mean 45 minutes, 10 times a season. It means letting them play.
"I think more managers are starting to realise, with the huge money in the Premier League – and yes, it is great to have that money in the bank – that it is great to be able to develop a club with those resources that come in, along with bringing through your own.
"Ronald Koeman has spoken about that and bought young players, so why not promote them from within as well?"
Calvert-Lewin took on Everton's lone striking role in the recent draw at Manchester City and excelled in the position, running ragged City's expensively assembled defensive trio of Vincent Kompany, Nicolas Otamendi and John Stones.
Collymore is nevertheless warning it won't all be plain sailing from here on in for the Yorkshireman.
But, with careful nurturing, he insists Calvert-Lewin is destined to operate at the apex of the game for years to come.
"He will need a bit of patience, because most of the youngsters I have ever seen, besides the truly exceptional ones, will have peaks and troughs – good games and bad games," said Collymore.
"I think the fact Dominic has said, 'I want to be involved, give me an opportunity', gives you an insight into the character of a player who will have a long and successful career for his club and country."
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Sleep Apnea – How is age a risk factor?
Sleep disorders can lead to a number of health problems and can sometimes be life-threatening. Sleep apnea is a condition characterized by breathing shortness when the patient is sleeping. As a result of breathing pauses which occurs several times, the patient wakes up frequently during sleep. This does not allow him/her to get sound sleep. As a result the sleep cycle gets affected leading to health issues. At our dental office we diagnose and treat patients who are suffering from sleep apnea. Our sleep apnea appliances and treatment has helped many patients from Calgary and surrounding communities get better sleep. The following write-up tries to provide an overview of how age is related to sleep apnea.
Sleep Apnea – How does age affect the sleep disorder?
Many studies conducted till date has associated sleep apnea with obesity, alcohol consumption, smoking and other risk factors. Age too has been commonly listed among risk factors. But how far is it true that age affects sleep apnea?
The statistics available till date show that sleep apnea is not very prevalent in children. Though the statistics are low, one should note that children too can be affected by the sleep disorder. In children who are diagnosed with the sleep apnea, the problem seems to be caused because of enlarged tonsils, obesity, exposure to tobacco smoke and respiratory infections.
On the other-side, sleep apnea seems to be more prevalent in people who are more than 40 years old. One of the main causes for the problem is found to be increased fat deposits around the neck region. Genetics, alcohol consumption, obesity and other factors can contribute to fat deposits around the neck. The sleep disorder can lead to hypertension, cardiac problems, stroke and other bodily conditions. Therefore diagnosis and treatment of sleep apnea is absolutely necessary to lead a healthier life.


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By Paige Weber
Describes the heritage of style of local american citizens, in either North and South the US, and the British and French colonists of North America.
Early the USA covers the areas of South the USA, relevant the US, and North the USA, from the times of the earliest indigenous peoples till the arriving and cost of colonies during the overdue 1700s. starting with the background of weaving within the Andes and the evolution of textiles, this hugely illustrated consultant discusses every thing from usual Inca, Mayan, and Aztec garments and ceremonial put on to early local American tribes in North the US to British and French colonial types and their effect within the New World.
Coverage comprises pilgrim clothing, Quaker kind, homespun textile, Dutch Colonial dress, knickerbockers, local costume of African slaves, the cotton undefined, the creation of Spanish and Portuguese colonial dress, and the army uniforms of the French, British, and innovative armies.
Read Online or Download Early America (History of Fashion and Costume) (Volume 4) PDF
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Commonly, it took the form of a half-moon, and used to be made up of steel so skinny and sharp that it can be used as a knife. Manco Capac, the 1st Inca ruler, on the solar pageant that he initiated. nine Inca Aristocracy The Inca rulers loved the softest clothing coated in tocapus, the main worthy jewellery, and the main extravagantly plumed headdresses. Entitlement to put on elaborations like feathers, infrequent shells, turquoise, gold, and silver used to be reserved solely for royalty, the the Aristocracy, and the highest-ranking army officials. humans from everywhere in the Inca Empire despatched tributes of infrequent garments and jewellery to the emperor, and likely materials, feathers, and colours have been claimed for his use on my own. Royal and noble Inca humans groomed themselves good, usually bathing in deepest bathtubs adorned with colourful minimize stones. The Sapa Inca the 1st Inca ruler Manco Capac is portrayed donning huge, immense, spiralling, gold rings and a richly coloured gown. Ear Plugs donning huge, immense plugs within the reduce a part of the ear, as regards to the lobe, was once an indication of significant prestige between Inca noblemen. younger noble boys acquired their first ear piercings and ear plugs through the annual most appropriate pageant, after they have been first famous as adults. The fabrics, colours, and dimension of a man's ear plugs indicated his prestige. those ear plugs have been as a result made as huge as attainable, and have been composed of invaluable metals and infrequent stones. via donning them, noblemen constructed stretched ears. The Spanish conquistadors referred to as the Inca the Aristocracy orejones, or "big ears. " inside of Inca society, although, those huge ears have been thought of prestigious. 10 The observe Inca applies to the Inca humans, and likewise to their emperor. The Sapa Inca, as he used to be recognized, wore a brand new outfit each day. He very infrequently wore any garment greater than as soon as. as an alternative, after he wore a garment, it used to be saved for 12 months after which burned in a distinct rite. The Sapa Inca wore not just vicuña hair tunics adorned with infrequent shells, beads, feathers, and gold threads, but in addition outfits made up of the rarest of fibers, equivalent to bat hairs. lots of his outfits have been woven in temples via the Virgins of the sunlight, secluded girls selected for this function on the age of 8. The emperor wore a royal, ceremonial headdress referred to as a llautu. It used to be a turban of many coloured folds that wrapped round his head, with a crimson-tasselled, vicuña-wool fringe The Incas held over his brow by way of a cloth band, crowned with feathers from the infrequent coraquenque chicken. different royal relations wore cloth headbands with royal fringes of gold and woolen tassels, however the pink colour used to be reserved for the Sapa Inca merely. infrequent Plumes The Inca royalty and the Aristocracy have been very keen on plumed headdresses, which tested to others their privileged prestige at a look. Prized feathers integrated these of falcons, eagles, hummingbirds, herons, and egrets. The conquered tribes of the Amazon despatched the Sapa Inca significant macaw feathers as homage, which he wore in ceremonial headdresses and enthusiasts.


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It's time for a makeover !
What's Up
After six years delivering what's NEW and NEXT in the heart of the capital, the iconic W London – Leicester Square is excited to announce a complete redesign of its public area bar and lounge spaces: W Lounge, Library and Room 913. Once complete, the new W Lounge will offer a bold new design and unique programming to Londoners and international jetsetters alike.
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Designed to reflect the 24/7 energy of both the W brand and the British capital, the new bar will feature subtle, abstract references to London's fashion, music and design influences and will add layers to the original hotel design inspired by the dual personality of the British soul.
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no subjectDate: 2009-07-29 01:01 pm (UTC)
I am highly amused at the timing of this post. I rarely spend money on orange juice; I usually think of it as being in the "gosh I wish I could afford that" category...but this week I'm trying to convince myself that I'm not as poor as I think I am, so I bought a big ol' Tropicana Orange Juice With Extra Pulp as a luxurious treat. So I'm sitting here drinking this orange juice, which I never have, and here I find this post. ZING!
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text: Journal of Animal Ecology Explore this journal > Explore this journal > Next article in issue: Mechanistic models of animal migration behaviour – their diversity, structure and use Next article in issue: Mechanistic models of animal migration behaviour – their diversity, structure and use View issue TOC Volume 82, Issue 3 May 2013 Pages 495–497 In FocusInadvertent consequences of fishing: the case of the sex-changing shrimpAuthorsIsabelle M. CôtéCorresponding authorDepartment of Biological Sciences, Simon Fraser University, Burnaby, BC, CanadaSearch for more papers by this authorFirst published: 15 April 2013Full publication historyDOI: 10.1111/1365-2656.12074 View/save citationCited by (CrossRef): 0 articles Check for updates Citation tools Set citation alert Citing literature Correspondence author. E-mail: email@example.com Hokkai shrimp Pandalus latirostris starts life as a male, but eventually turns into a female given the right size and social conditions. The traps used in the fishery targeting this species selectively retain the larger females, leaving a severely male-biased sex ratio in nature and social conditions that bear no resemblance to those that prompted (or prevented) sex change. Photo: Susumu Chiba Chiba, S., Yoshino, K., Kanaiwa, M., Kawajiri, T. & Goshima, S. (2013) Maladaptive sex ratio adjustment by a sex-changing shrimp in selective fishing environments. Journal of Animal Ecology, 82, 631–640. Fishing can have many unintended consequences. In this issue, Chiba et al. (2013) demonstrate that size-selective harvesting of a sex-changing shrimp effectively voids their normally adaptive adjustments to population sex ratio. The shrimp's 'decision' to change sex depends largely on the relative abundance of mature males and females in early summer, before fishing begins. However, fishing traps selectively retain females, leading to heavily male-biased sex ratios at the onset of autumn breeding that are different from the ratios that influenced sex-change decisions. Although this phenomenon is not yet expressed in catch trends, maladaptive sex-change decisions could ultimately affect population productivity and persistence. Continue reading full article Enhanced PDFStandard PDF (226.8 KB)


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Ye Tao1#, Zhongjun Yan2#, Ce Liu3, Jianjie Ma3, Wei Wei Xu1, Qinghua Yang1, Wei Fang2* and Yifei Huang1*
1Department of Ophthalmology, General Hospital of Chinese PLA, P.R. China
2Department of Neurosurgery and Institute for Functional Brain Disorders, Tangdu Hospital, Fourth Military Medical University, P.R. China
3Department of Medical Administration, Beidaihe Sanatorium of Chinese PLA, P.R. China
Received date: April 18, 2017; Accepted date: June 06, 2017; Published date: June 11, 2017
Citation: Tao Y, Yan Z, Liu C, Ma J, Xu WW, et al. (2017) Rbap48 Could Act as a Candidate Biological Predictor for the Cognition Impairments of Patients with Temporal Lobe Epilepsy: A Hypothesis Based on Recent Molecular Findings. J Clin Case Rep 7: 970. doi: 10.4172/2165-7920.1000970
Copyright: © 2017 Tao Y, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Visit for more related articles at Journal of Clinical Case Reports
The temporal lobe epilepsy (TLE) is characterized by the neurodegeneration, abnormal reorganization of circuitry, and the loss of functional inhibition in hippocampus regions. Particularly, the declined neurogenesis in hippocampus has emerged as a significant hallmark of TLE. RbAp48, which is initially recognized as a retinoblastoma binding protein, is also identified as a positive regulator of human neurogenesis owing to its ability to regulate the expression of the pluripotency, differentiation, and cell cycle genes in human PSCs. The deficiency of RbAp48 critically contributes to the dentate gyrus (DG) dysfunction and is closely related to age-related memory deficits. Nevertheless, the roles of RbAp48 in the neurogenesis deterioration and memory loss of TLE patients remain to be determined. In view of the linkage between the deficiency of RbAp48 and the TLE-related memory loss, it is reasonable to hypothesize that the expression level of RbAp48 in the hippocampus of the TLE patients might be down regulated in accordance with the reduced neurogenesis. As the neurogenesis exhibits a close relationship with the hippocampal functions like learning and memory, the RbAp48 would possibly act as a candidate biology predictor for the cognition impairments of the TLE patients. This notion might cast insights into the etiology of hippocampusbased memory loss in TLE patients with the potentials of opening up new therapeutic avenues.
Temporal lobe epilepsy; Hippocampus; Cognition
Temporal lobe epilepsy (TLE) is a common neurological disorder that characterized by the spontaneous recurrent unprovoked seizures, cognition impairments, memory loss and depression [1]. Currently, the precise cause contributes to TLE and the underlining pathological mechanism is not totally clear. Pharmacologic therapy represents the first line of treatment for TLE and is effective in most cases. However, approximately one-third of patients develop intractable seizures that cannot be controlled by a wide variety of anti-convulsive drugs [2]. Recent research found that this disorder is associated with neurodegeneration, abnormal reorganization of the circuitry, and loss of functional inhibition in the hippocampal regions [3-5]. Particularly, the declined neurogenesis in hippocampus has emerged as a significant hallmark of TLE. Research based on the epilepsy patients and animal models have found various kinds of reduced neurogenesis in hippocampus, including the reductions in gamma-amino butyric acid-positive (GABAergic) neurons, disappearance of the calbindin in a substantial fraction of dentate gyrus(DG), and the decreased concentration levels of multiple neurotrophic factors such as BDNF, FGF-2, IGF-1. As the neurogenesis exhibits a close relationship with the hippocampal functions like learning and memory, it is proposed that these changes collectively contribute to the complicated features of the TLE patients [6]. However, the detailed molecular mechanisms underlying the cognition impairments of TEL patients are not completely understood.
The histone-binding protein rbbp4 (RbAp48) is a ubiquitously expressed nuclear protein and associated with various functions including mediating chromatin metabolism and assembly, ras signaling, cytoskeletal reorganization, and modulation of cell proliferation [7-10]. RbAp48 is required for the maintenance of multiple human pluripotent stem cells (PSCs) types, such as neural stem cells (NSCs), embryonic stem cells (ESCs) and embryonal carcinoma cells(ECCs) [11]. Decreased expression of RbAp48 concomitantly reduces the expression of the PSCs -specific genes, which are involved in the regulatory network of organogenesis, particularly the neurogenesis. Thus RbAp48 is considered as a positive regulator of human neurogenesis owing to its ability to regulate the expression of the pluripotency, differentiation, and cell cycle genes in human PSCs. Moreover, the deficiency of RbAp48 plays a pivotal role in the DG dysfunction and it is closely related to agerelated memory deficits [12]. The human hippocampus can be affected by a large variety of very different neurological diseases, of which the epilepsy, acute ischemic stroke, transient global amnesia, and limbic encephalitis are the most common causes [13].
The roles of RbAp48 in the neurogenesis deterioration and the complicating memory loss of TLE patients are left to be determined. No study has so far examined changes in RbAp4 expression as a function of epilepsy severity. Therefore, it is valuable to investigate the expression levels of RbAp48 in the hippocampus of the TLE patients and explore the underlying implications of the possible regulation. It was particularly notable that the cognitive impairments and especially memory disruption are the major complicating features of the TLE and they have been considered as the most problematic comorbidity [14,15]. Patients with a longer duration of refractory TLE would exhibit more severe cognitive impairments. Understanding of the neurobiology of disordered cognition especially the memory loss in epilepsy was accelerated by the development of organized epilepsy surgery programs and neuropsychology research [16,17]. However, it remains to be challenging to elucidate the origin of cognitive abnormalities, the progression mold, and most importantly, how to predict and protect the cognitive function of TLE patients. Extensive investigations have focused on the hippocampus to form a conceptual framework of the architecture of diverse memory systems. It is well understood that RbAp48 participates in the age-related DG dysfunction and the expression level decreases in ageing hippocampus of human and mice [12,18]. The deficiency of RbAp48 in the DG has been suspected as the underlying cause of age-related memory deficits. Therefore, the TLE probably result in RbAp48 deficiency and this decline might reflect a preferential vulnerability of memory processes in the hippocampus of TLE patients. Meanwhile, the specific deficiency of RbAp48 in the TLE hippocampus might be associated with the high occurrence of memory disruption in the TLE patients. It is evidenced that maintenance of hippocampal-dependent learning and formation of memories require the continuous addition of newly functional granule cells [19]. From this perspective, the impaired neuronal differentiation of NSCs and the decreased neurogenesis that caused by down-regulated expression of RbAp48 may significantly contribute to the cognitive deficits of TLE hippocampus.
In view of the potential linkage between the RbAp48 deficiency and the memory loss, it is reasonable to hypothesize that the TLE hippocampus might be exposed to a preferential vulnerability of postoperative memory decline. Based on the aforementioned findings, we propose that the expression levels of RbAp48 in the hippocampus of TLE patients might be down regulated in accordance with the reduced neurogenesis. As the neurogenesis exhibits a close relationship with the hippocampal functions like learning and memory, the RbAp48 could possibly act as a candidate predictor for the cognition impairments of the TLE.
Evaluation of the hypothesis
The present hypothesis proposes that the cognitive deterioration in TLE patients might be closely related to the deficiency of RbAp48 in the hippocampus. This notion might cast insights into the etiology of hippocampus-based memory loss in TLE patients with the potential of opening up new therapeutic avenues which are rarely touched on. The hippocampus specimens of TLE patients who are subjective to surgery should be collected for the evaluation of our hypothesis. These patients should be diagnosed by multiple methods, including the high-resolution magnetic resonance imaging (MRI), positron emission tomography (PET), long-term video electroencephalography (EEG), and intraoperative electrocorticography (ECOG) according to the International Classification of Epileptic Seizures by the International League against Epilepsy. Further research should demonstrate the utility of multiple measurements, including the immunohistochemistry, real-time PCR and West blotting to quantify the expression level of RbAp48 in the hippocampus tissues of TLE patients. The expression levels of RbAp48 protein in the hippocampus tissues of these TLE patients should be directly detected by immunohistochemistry examination using an antibody directed against RbAp48. Furthermore, the expression levels of RbAp48 protein in the TLE hippocampus should be quantitatively determined by Western blotting, and the expression levels RbAp48 mRNA should be quantified by real-time PCR. These methods, both individual and in combination, might consistently point to the decreased level of RbAp48 in the hippocampus of TLE patients in comparison with age-matched intact hippocampus.
Furthermore, it had been found that up-regulation of RbAp48 in the DG of aged wild-type mice ameliorated their age-related memory loss, and restored their memory to youthful vigor [12]. So it is a logical next step to test these RbAp48 expression enhancers for therapeutic use against the memory deterioration in TLE animal models, and ultimately in TLE patients.
As the disparate response in the chronic stages of TLE, the decreased hippocampus neurogenesis has received considerable attention which sought to elucidate the pathophysiology of this disorder [6]. Both studies on the hippocampus of TLE patients and TLE animal models clearly demonstrate that the DG neurogenesis is substantially down regulated. Several neurotrophic factors, such as FGF-2, IGF-1, BDNF, and GDNF, are considered as the positive regulators of neurogenesis in the hippocampus. The concentrations of these neurotrophic factors are decreased during chronic epilepsy [5,20]. Therefore, it is reasonable to deduce that the dramatically declined neurogenesis during chronic epilepsy might be caused by the decreased levels of the aforementioned neurotrophic factors.
The RbAp48, which is characterized by the component of distinct nucleosome-modifying complexes, is initially identified as a retinoblastoma binding protein [21,22]. It has been found that the RbAp48 plays a pivotal role in maintaining human PSCs pluripotency, and is regarded as a positive regulator of human cell differentiation. Regular expression of RbAp48 can facilitate human PSCs, especially the NSCs maintenance, by promoting or permitting expression of a combination of known pluripotency genes and cell cycle regulators (e.g., NANOG, CCNA2 CCNB1) [11]. The decreased level of neurogenesis is consistent with the disruption of a complex shared network which maintains the differentiation of NSCs by a specific controlling program. In view of the crucial functions of RbAp48, it is possible that the decreased expression of this protein might be at least partially contributes to the neurogenesis disruption. The deficiency of RbAp48, together with other changes in the microenvironment of the TLE hippocampus, might mutually influence the overall declined hippocampus neurogenesis. This novel hypothesis originates from the memory defects of TLE may be instrumental to clarify the underlining pathogenesis mechanism of this disease.
NSCs can retain their latent developmental potential while proliferating rapidly. It was found that NSCs survived even in the chronic epilepsy hippocampus, and produced new cells to the levels similar to the age-matched intact hippocampus [6]. However, TLE hippocampus is associated with considerable (95%) decline in neuronal differentiation of the newly born cells in comparison to the age-matched controls [23]. As the TLE does not interfere with the production of the new cells derived from NSCs, thus reduced expression of RbAp48 would not affect the production or survival of the newly born cells, but it does appear to interfere with the neuronal fate choice decision of these newly generated cells [11]. Therefore, decreased expression of differentiation regulator Rbap48 in the TLE hippocampus may suppress the pluripotency of NSCs by instructing them to remain in an undifferentiated state and/ or to switch into the glial fate, rather than the hippocampus neurons. Either or both of these possibilities can reduce the overall neurogenesis during TLE. Thus radically diminished neurogenesis during TLE may act as a consequence of the dramatic decrease in the neuronal differentiation of the newly born cells.
Deficiency of the RbAp48 is likely to dampen the neuronal differentiation of newly born cells derived from NSCs. Therefore, it might potentially be a target for developing future therapeutic strategy for TLE.
It is possible that the maintenance of certain concentration of RbAp48 as well as other neurotrophic factors that promote neuronal differentiation of newly born cells are beneficial for enhancing neurogenesis in the hippocampus. Some innovative studies have demonstrated that grafting of NSCs appears to be a promising approach for improving hippocampal function [24,25]. Moreover, it was evidenced that grafting of NSCs is efficacious for improving neurogenesis in the aging rat hippocampus [26]. In this context, administration of the exogenous RbAp48 as well as other neurotrophic factors into the epileptic hippocampus may stimulate neurogenesis from endogenous NSCs that survive even in the chronically epileptic hippocampus. Persistence of NSCs during TLE is encouraging for developing strategies that have the ability to facilitate improvements in the NSCs generation, expansion, and differentiation. Considering the blood-brain barrier might be leaky during TLE, subcutaneous or systemic administrations of RbAp48 in combination with other neurotrophic factors appear to be a promising treatment.
In addition to providing a novel target for TLE treatment, RbAp48 may also act as a potential predictor of the postoperative memory outcome. As a substantial part of TLE patients endure a worse memory after epilepsy surgery, the post-operative memory performance is of great importance in deciding a reasonable surgery mode and resection scope. A combination of factors including side of resection, baseline memory performance, extent of hippocampal sclerosis, chronological age, and Wada Test performance all provided information regarding prediction of memory outcome. However, the specific biomarkers that forecast the development of cognitive deficits have not been identified and there are relatively few strategies to identify whether the individual TLE patients is at the risk for postoperative cognitive dysfunction. The pioneering researches which fortunately gain access to the resected TLE hippocampal tissues would be instrumental to testify the exact expression levels of RbAp48. Future refinement of that knowledge over time as informed by the postoperative follow up of the patients with RbAp48 deficiency may identify a candidate biology predictor for postoperative cognition.


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Issue 2
Fall 2011
The Student Union's purpose is to serve as a P.L.A.C.E for students of both commuters and residents. Play Learn Ask Convene Eat However, this is the HOME away from HOME for commuters. With the many improvements, there is so much to do here at the Union! There are brand new equipment tables, new food services, new computers, and programs going on at all times of the day! The Student Union is the hearthstone of our campus. It is the only building on campus that is for the students, by the students, with the students. It creates a common space for everyone enrolled at New Paltz to engage and reflect during their time here. HOURS OF OPERATION Monday-Friday: 7:30 AM - 12:00 AM Saturday-Sunday: 9:00 AM - 12:00 AM
Want to know more about events going on campus? Join the Off Campus commuter Facebook page! https://www.facebook.com/pages/SUNY-NewPaltz-Off-Campus-Students/148172945267062
Student Shoutout…Whats going on?? New Paltz Solar Car meetings are held every Tuesday at 3pm in Resnick Engineering Hall (REH) 109, and new members from all majors are welcome and encouraged to join!
Asian Students Association
We hope everyone is having a great first few weeks of school! The Muslim Student Association is holding General Interest Meetings every Monday at 6:30 pm in SUB 408. Everyone is welcome to attend. We will discuss various events that we are planning on doing throughout the semester. All suggestions are welcome. Thank you very much and hope to see you all there!
GI/weekly meetings. Tuesdays at 8pm in SUB 402.
Volunteer Fair September. 20th from 11-3 in the Student Union MPR !
Urban Lyrics. We are going to be holding our GI meeting for our Urban Spoken Word Team on Monday September 19th 6-8pm in SUB 401/405 and then auditions will be Monday September 26th 6-8pm in SUB 401/405.
The SUNY New Paltz Up 'til Dawn student Executive Board would like to invite you to participate in our exciting Up 'til Dawn fundraising event benefiting St. Jude Children's Research Hospital. The Annual Up 'til Dawn Event will be held October 5, 2011 from 7pm to 11pm at SUNY New Paltz Student Union MPR. More than 300 students, parents, and faculty are expected to participate in this event packed with fun events and most importantly, raising money for the children of St. Jude. St. Jude Children's Research Hospital is internationally recognized for its pioneering work in finding cures and saving children with cancer and other catastrophic diseases. St. Jude shares its research findings freely and families without insurance are never asked to pay. Hope to see you all there : )! Co-President-Julia Spellman
Hey Commuters! Come check out New Paltz's Ultimate Frisbee Team! GUNX PRACTICE SCHEDULE Monday Tuesday Wednesday Coed 4:30-6pm South Lawn† Men 5-6:30pm 4:30-6pm Rec West* Rec West* Wome 4:30-6pm n South Lawn† *Rec West is the field behind the turf/track. †South Lawn is the field to the left of the gym.
4:30-6pm Rec West*
Friday 4:30-6pm South Lawn†
Meet student activities and union services Mike Patterson Director of Student Activities and Union Services
Naomi Vogt Keyboard Specialist of Student Activities and Union Services
Brendan O'Brien Event Coordinator of Student Activities and Union Services
Nicole Shanahan Graduate Assistant of Student Activities and Union Services
Emily Spilman Assistant Director of Student Activities and Union Services
A Note from Tara Welcome to New Paltz First-Year Commuters! I hope you're enjoying your classes and adapting well to your new college schedule. As a reminder, you can look forward to receiving announcements throughout the academic year from the Commuter Assistants as well as from your Orientation Leader and from me as well. In addition to commuter related activities, I'll be in contact with you about upcoming First-Year Friday and Saturday Nights @ the Terrace events. You can find the schedule of events online at www.newpaltz.edu/keepingyouposted. See you around campus & have a wonderful fall semester! Tara Sestanovich Coordinator of First-Year Programming firstname.lastname@example.com
Rent a locker! Lockers are available to students for $10.00 a semester with a $10.00 deposit. The Office of Student Activities and Union Services will start taking reservations on August 2nd, 2011. After you are done with the locker, whether you rent for the semester or year, you receive your deposit back, given there is no damage to the locker itself. The lockers are located in the lower level of the atrium close to the gaming equipment and bookstore. This is a great way for the commuter to have a place of their own in the Union. With renting a locker you won't have to haul around heavy books, winter jackets, boots, or any "stuff" you don't need throughout the day. If you are interested feel free to contact Nicole Shanahan in SU 211 or call 257.3025
Community for you! NEW PALTZ UNWTRAPPED
Tuesday. September 27th 3pm-4pm Student Union 418 COMMUTER DINNER PARTY
Monday, September 19th 5pm-6pm Student Union 418 SPIRIT WEEKEND
September 23-25th ALL WEEKEND! Fun, Games and more! Crispell Hall 8pm on Friday!
Riddle of the month! Complete this sequence of letters: o, t, t, f, f, s, s, _, _, _. **The first 5 students who email me with the correct answer will be entered into a raffle! firstname.lastname@example.com
Want to hear about all the FUN ON campus!? Student Activities is able to contact you via blackboard on the commuter listserv! Important information about events and activities pertaining to the off campus population are sent through this! Also, the NP Alert system is available and provides students an opportunity to have notifications of events sent to their phone and/or email. Groups available: • New Paltz Student Activities: Occasional text messages will be sent to you promoting select events on campus • Off-Campus/Commuter Students: The Office of Student Activities and Union Services will use this group to send updates for off-campus students for things such as: Commuter Appreciation Days, Off-Campus Student Socials, Off-Campus Student Union events and promotion, Commuter Locker Rentals and PROGRAMMING! Directions for NPAlert: 1. Login to http://my.newpaltz.edu 2. Go to Student Services tab 3. In the NP Alert channel: Follow the link to login to manage your account. On the NP Alert/Rave Wireless page, login on the top left side with the same username and password you used to login to my.newpaltz.edu.


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Movie South Park Spontaneous Combustion () download free
Book Title: South Park Spontaneous Combustion
Directors: Matt Stone
Genre: Animation, Comedy
Release Date: 1999-04-14
Runtime: 22 min
Stars: Trey Parker,Matt Stone,Mary Kay Bergman
IMDb Rating: 8.3
Country: USA
Language: English
Full movie description "South Park Spontaneous Combustion":A wave of spontaneous combustion is sweeping through South Park, and the mayor charges Stan's father (a geologist) with finding the cause. After working feverishly on the problem, he finds the answer: people are holding in their farts for so long, they're bursting into flame. A grateful nation loosens its sphincters in relief, but their problems aren't over yet. Meanwhile, the boys crucify Cartman in the hopes of helping Kyle's father get an erection.
Reviews of the South Park Spontaneous CombustionSpontaneous Combustion is a very funny and interesting South Park episode.It shows another example of how young children do not understand things and try to help but they are all wrong.Kyle's dad cannot get an erection and that's why his parents keep arguing.The boys try to find an erection for Kyle's dad and they misinterpret "resurrection" for erection after Father Maxi tells them they should preform the resurrection of Jesus Christ in a play.They hang Cartman up on a cross so he can get an "erection" and give it to Kyle's dad.Meanwhile, everybody in South Park starts "Spontaneously Combusting" and it's up to Randy to find out the solution(even though he is a geologist).He finds that not holding in farts will keep people from combusting, however the excessive farts cause damage to the air.Everybody is now angry at Randy because they do not know how to stay alive! This is a funny and interesting South Park episode.
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Global Markets: Grains – India to Import Wheat While Exporting Ample Rice
India is a significant player in global food grain trade. It is the second largest producer of rice and third for wheat. Government policies have encouraged production of these two staple grains, which are forecast at record levels. Despite bumper crops, the country's food grain trade is moving in opposite directions as the stocks situation diverges.
In response to diminishing wheat stocks, the government eliminated the import tariff on wheat in December. However, GOI reinstated the policy in March before the local harvest began. While India wheat production is up ten percent, it is not enough to meet growing food demand and replenish stocks after two poor harvests. As a result, India is forecast to be a net importer for the second consecutive year.
In contrast, the record rice crop is forecast to not only supply the domestic market but also the world as India remains the top global supplier. The rice stocks remain ample and still well above the desired buffer level, aiding Indian competitiveness. Meanwhile, second-largest exporter Thailand has held numerous auctions to reduce government-held stocks, recently pressuring their prices higher.
The relative availability of Indian food security stocks has been the key driver for food grain trading behavior. A decade ago as global food prices were escalating, the government banned exports of wheat and non-basmati rice. Stocks grew with expanding production. Exports resumed in 2011/12, and India became an exporter of both grains. Now as stock levels have diverged, India is a wheat buyer and rice seller.
Dicamba Faces State Restrictions Based on Weed Science Data – DTN
Among all the buzz and blame surrounding the dicamba injury crisis of 2017, Purdue University weed scientists Bill Johnson and Joe Ikley have tried to answer a simple question for