text:
Shawn Sadowski - My New Enterprise.
Shawn is currently planning on embarking on a cross country 4,000 mile bike journey to interview America's best entrepreneurs. He will be riding from the west coast of Oregon to the East coast of Virginia. You can support his tour by backing his kickstarter campaign that will launch April 29th. Register here to be notified when it goes live: http://prefundia.com/projects/view/my-new-enterprise-tour-2014/1193/
What is the name of your business and what type of industry are you in?
My New Enterprise – We are an entrepreneurial training and film production company. We travel the world documenting the stories of successful entrepreneurs and helping business owners grow their companies.
How old where you when you started your first business?
I was 24 years old when I first started a software company for the transportation industry.
How did you know you were an entrepreneur?
I've always been very independent. As a kid, I used to tell my mom that I wanted to "own hotels" when I grew up. After I graduated from high school, I took a two-year sabbatical to Europe. When I got back to the States, I bounced around from job to job for a few years while I was looking for the right business to start. After a failed stint as a ski bum and restaurant server, I finally decided to take the leap and started my first company. Things didn't always go smoothly with that company and I made a lot of mistakes, but it was the best professional decision I ever made.
What is something you do on a daily basis that you believe aids in your success?
Exercise – It helps me clear my head and focus. I also try to do something fun that makes me laugh every day.
What is best advice you received while starting your business?
Fail quickly and cheaply.
What advice would you give to someone who is thinking about starting a business?
Fail quickly and cheaply. (Best advice I ever received.)
Also, things will not go the way you expect them to go, so be prepared to pivot and change directions.
What is one resource you cannot run your business without?
We couldn't run our company without great mentors and advisors. I've tried to build a network of successful business builders whom I respect and who are willing to provide guidance. When I have a question or my business is facing a challenge, I am always quick to ask for help.
What is the best book you have read this year?
Two actually:
Financial Intelligence by: Karen Berman and Joe Knight
Leadership and Self-Deception by: Arbinger Institute
How can we connect with you?
Twitter: @mynewenterprise Personal Twitter: @shawnsadowski
Open advice or words of wisdom:
I talk with people all the time who have great business ideas. In fact, almost everyone has an idea. Unfortunately, there is a big difference between a great business idea and a real business opportunity. I have found that a real business opportunity typically consists of the following components: (1) An idea for meeting or better meeting a need, (2) A credible position within the industry, (3) The resources needed to implement the idea, and (4) Customers who are ready to buy the product RIGHT NOW!
Some aspiring entrepreneurs believe a "great idea" is everything (component 1), and that anyone can turn it into a business. While this may have been true in past decades, today's ever changing economy requires excellent execution of the idea (components 2, 3 and 4). When all four components align themselves, starting a business becomes much less risky and successful entrepreneurs will typically have the courage to take the risk and face the challenge.
HERE IS THEIR KICKSTARTER VIDEO: Please support these guys in any way you can, there an awesome bunch and doing great stuff for the entrepreneurial community!


text:
Pmt 1% w/w Soap
Nemus Pharmaceuticals Pvt Ltd
Composition for Pmt 1% w/w Soap
Primarily used for
75 gm in 1 packet
1 Packet
Medicine Overview of Pmt Soap
Uses of Pmt Soap
Pmt 1% w/w Soap is used in the treatment of scabies.
Side effects of Pmt Soap
Erythematous rash, Itching, Dry skin, Paresthesia (tingling or pricking sensation).
How to use Pmt Soap
Use it as advised by your doctor or check the label for directions before use.
How Pmt Soap works
Permethrin is a pyrethroid compound and it belongs to a class of medications called as Ectoparasiticides. It acts on the nervous system of variety of pests including itch mite and head and pubic lice causing paralysis and death.
In Depth Information on Pmt Soap
Expert advice for Pmt Soap
- Inform you doctor if you have any skin conditions or allergies to medicines, food or other substances, asthma, or if you have any other medical conditions.
- Avoid contact with eyes and mucous membranes and wear gloves to avoid irritation to hands. If permethrin is accidentally introduced into the eyes, rinse immediately with plenty of water.
- Apply the medication on small part of the hair to ensure it does not affect coloured or permed hair before application to entire head.
- Check hair for active infestation with lice or nits after one repetition of treatment after 14 days as you may be at risk of developing resistance to treatment.
- Tell your doctor if you are pregnant or planning to become pregnant or are breastfeeding.
Special precautions for Pmt 1% w/w Soap
No interaction found
Pmt 1% w/w Soap is probably safe to use during pregnancy.+more
Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor....
Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
Pmt 1% w/w Soap is probably safe to use during lactation. L+more
imited human data suggests that the drug does not represent a significant risk to the baby....
Pmt 1% w/w Soap does not usually affect your ability to drive.
There is limited information available on the use of Pmt 1%+more
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There is limited information available on the use of Pmt 1%+more
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Missed Dosage
If you miss a dose of Permethrin, please consult your doctor.
Patient Concerns
Frequently asked questions for Pmt 1% w/w Soap
Frequently asked questions for Permethrin
Pmt is not an over the counter medicine. It is sold only upon a prescription by a registered medical practitioner.
Substitutes for Pmt Soap
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subset: commoncrawl


text:
van Riemsdyk, 27, has one-year left on his contract after this season and comes with an affordable annual salary cap hit of $4.25 million. He also owns a limited no-trade clause where he can list up to 10 teams he will not accept a move to.
Several teams are in the market for a top-line sniper, specifically one who can play the left wing, and van Riemsdyk's attractive contract ups his value.
The Maple Leafs are not against moving JVR, but the club will want a top-tier defenseman as part of any trade, especially one made prior to the March 1 trade deadline.
With the Leafs in the thick of things in the Atlantic Division playoff race, Leafs GM Lou Lamoriello can drive an even harder bargain with teams interested in his winger.
The Anaheim Ducks, Minnesota Wild, Pittsburgh Penguins and Los Angeles Kings have expressed some form of interest in van Riemsdyk in the past, though it's unclear if trade talks with any of those clubs are ongoing.
The Penguins almost acquired van Riemdsyk in the summer of 2015, but made a move with the Leafs to bring in Phil Kessel, instead.
It's believed talks with the Wild may have centered on defenseman Jonas Brodin.
In 37 games with the Leafs so far this season, van Riemsdyk has registered 13 goals and 15 assists for 28 points.
Latest Issue |
Subscribe |
Buy Back Issues


text:
Search 321,000 hotels worldwide.
Get the price guarantee available for your trip.
No Expedia cancellation fee to change or cancel almost any hotel reservation.
We had a lovely room that fit all our needs. We were located close to food, the slopes and other ski locations. I would stay here again!
Great location. Friendly staff. Clean room. Lots of activities.
Very pleased with the condo and the décor. Clean, and comfortable.
We love Keystone and this is a great place to stay.
First, both the hotel staff who worked there were outstanding. I did not get the woman's name but she checked us in and she was wonderful. Edward was fantastic and he is such a great person to have at any hotel. The rooms were so clean and very comfortable and I felt at home. This is a hidden secret ...
I was here for a meeting. So sweat and convenient resort!
Love it here, the compound is clean and well taken care. I will def. check it out again soon if im ever in again
Search for hotels in Keystone on Expedia. You can easily find your hotels in Keystone using one of the methods below:


text:
Scandinavian fashion line Bruuns Bazaar has launched its 2013 spring/summer lookbook with some simplistic and elegant results. Hailing from Denmark, Bruuns Bazaar was founded in 1994 by brothers Teis and Bjorn Bruun and were amongst the frontrunners of the progressing Scandinavian fashion scene. Offering a classic, sensible yet stylish approach to both casual and smart wear, Bruuns Bazaar focuses its brand on creating well-cut, understated and precise clothing. The new lookbook does not divert from this approach mixing contemporary fashion ideology with classic, bold designs. Pieces such as ankle-length trousers and fitted men's blazers set the trend for the subtle yet eye-catching tone carried throughout the lookbook. Visit the Bruuns Bazaar site to find out more.
- Fashion
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HYPEBEAST 100: The innovators from all realms of creativity in the spotlight.
With in-depth interviews, focused features and fashion-forward editorials, our print publication features long-form coverage of the topics valued by readers.
Explore and be inspired by the latest women's fashion news and trends.
- Videos
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text: Most of you know that I love Transformers and I'm sure that you do to. I remember before the Transformer movies came out these videos were all I had to drool over. Some are pretty good and some are stupid but either way - THEY ARE TRANSFORMERS AND THEY ARE REALLY GOOD DANCERS. Videos after the jump.


text:
Red Hat Bugzilla – Bug 254139
sound card problem in 101ggc motherboard
Last modified: 2008-08-02 19:40:35 EDT
Description of problem:I hav Intel 101GGC motherboard i installed linux fedora 7
after completion of installation the there was no sound heard during sound
playback during testing.It showed you can create /root/scsconfig.log and
/root/scsrun.log on the system tab and file a new bug...
I have attached scsconfig.log and pasted scsrun.log below in Additional
information column
Version-Release number of selected component (if applicable):
How reproducible:
Steps to Reproduce:
1.After installation there was no sound heard during playback during first time
Actual results:
Expected results:
Additional info:
------- System Config Soundcard Log --------
Fri Aug 24 01:39:46 IST 2007
ALSA lib pcm_hw.c:1357:(_snd_pcm_hw_open) Invalid value for card
aplay: main:545: audio open error: No such device
cat: /etc/asound.conf: No such file or directory
amixer: Mixer attach default error: No such device
But there is no problem with the source dvd when installed in other model
motherboards it works fine.... and the source also passed the image test..
Created attachment 172410 [details]
------- System Config Soundcard Log --------
ACPI: PCI Interrupt 0000:00:14.2[A] -> GSI 16 (level, low) -> IRQ 19
hda-intel: no codecs initialized
ACPI: PCI interrupt for device 0000:00:14.2 disabled
The driver isn't initialized. You have quite old ALSA drivers, please update
your kernel / user space packages (alsa-lib, alsa-utils) and check it again.
The information we've requested above is required in order
to review this problem report further and diagnose/fix the
issue if it is still present. Since there have not been any
updates to the report since thirty (30) days or more since we
requested additional information, we're assuming the problem
is either no longer present in the current Fedora release, or
that there is no longer any interest in tracking the problem.
Setting status to "CLOSED INSUFFICIENT_DATA". If you still
experience this problem after updating to our latest Fedora
release and can provide the information previously requested,
please feel free to reopen the bug report.
Thank you in advance.
Note that maintenance for Fedora 7 will end 30 days after the GA of Fedora 9.


text:
use the following search parameters to narrow your results:
e.g. subreddit:aww site:imgur.com dog
subreddit:aww site:imgur.com dog
see the search faq for details.
advanced search: by author, subreddit...
38 users here now
A place to discuss and share Progressive Rock music, and anything prog-related.
Add Band Name - Song Title to your music post titles.
No full album streams. Exceptions for promotional streams of new releases.
Images may only be submitted in self-post form.
No submissions that have already been posted within the past 6 months.
Other places to check out:
Please follow reddiquette. Don't downvote something if you don't like it. Instead, discuss it in the comments. Downvotes should be reserved for things that don't contribute to the community
For lower quality YouTube videos, please consider using Bandcamp as an alternative, if available.
A song I made with sax, a bad impression of a David Gilmour solo, and a Carl Sagan quote. (soundcloud.com)
submitted 4 years ago by [deleted]
there doesn't seem to be anything here
Use of this site constitutes acceptance of our User Agreement and Privacy Policy. © 2017 reddit inc. All rights reserved.
REDDIT and the ALIEN Logo are registered trademarks of reddit inc.
π Rendered by PID 52844 on app-456 at 2017-09-22 21:06:38.441153+00:00 running 287b538 country code: US.


text:
Combined Bone Marrow Transplantation (BMT) and Renal Transplant for Multiple Myeloma (MM) With End Stage Renal Disease (ESRD)
This study has been completed.
Massachusetts General Hospital
Information provided by (Responsible Party):
Thomas Spitzer, Massachusetts General Hospital
ClinicalTrials.gov Identifier:
First received: February 27, 2009
Last updated: April 13, 2015
Last verified: April 2015
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Detailed Description:
The primary objective is to cure multiple myeloma with less toxic allogeneic bone marrow transplantation while inducing renal allograft tolerance through mixed chimerism in patients with end stage renal failure and multiple myeloma
|Multiple Myeloma End Stage Renal Disease
|Drug: Cyclophosphamide, anti-thymocyte globulin Procedure: Kidney transplant Radiation: Thymic irradiation Procedure: Bone marrow transplant from a related donor
|Phase 1
|Study Type:
|Study Design:
|Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
|Official Title:
|Combined HLA-matched Bone Marrow and Kidney Transplantation for Multiple Myeloma With Renal Failure
Resource links provided by NLM:
Genetics Home Reference related topics: multiple myeloma
MedlinePlus related topics: Bone Marrow Transplantation Kidney Failure Kidney Transplantation Multiple Myeloma
Drug Information available for: CyclosporineU.S. FDA Resources
Further study details as provided by Thomas Spitzer, Massachusetts General Hospital:
Primary Outcome Measures:
- Remission status of multiple myeloma [ Time Frame: 3 years ]
- Renal allograft acceptance and ability to discontinue immunosuppressive therapy [ Time Frame: 3 years ]
Secondary Outcome Measures:
- Graft versus host disease (GVHD) [ Time Frame: 3 years ]
- Opportunistic infections [ Time Frame: 3 years ]
- T cell recovery and immune reconstitution [ Time Frame: 3 years ]
|Estimated Enrollment:
|Study Start Date:
|August 2001
|Study Completion Date:
|July 2014
|Primary Completion Date:
|July 2014 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: Bone marrow and renal transplant
Cyclophosphamide, anti-thymocyte globulin, thymic irradiation conditioning and kidney transplant and bone marrow transplant from a related donor for patients with multiple myeloma and end stage renal disease with cyclosporine for graft versus host disease prophylaxis
Drug: Cyclophosphamide, anti-thymocyte globulin
Cyclophosphamide 60 mg/kg IV on Day -5, -4 Anti-thymocyte globulin 20 mg/kg IV on Day -1, Day +1, +3, +5
Cyclosporine starting on Day -1 at 5 mg/kg daily I.V. and reduced to 3 mg/kg on Day +4, and adjusted to provide a trough whole blood concentration of 250-400 ng/mL. The route of administration will be changed to oral as soon as the patient is able to tolerate oral medications
Other Name: CyclosporineProcedure: Kidney transplant
On Day 0 the renal transplant is performed according to standard surgical techniques, preferably using an iliac fossa, extraperitoneal approachRadiation: Thymic irradiation
Thymic irradiation 7 Gy on Day -1Procedure: Bone marrow transplant from a related donor
• Donor bone marrow (> 2 x 108 nucleated cells/kg of recipient body weight) is prepared for infusion according to the standard procedure at the medical center. A total of 15,000 Units of heparin is mixed with the marrow, which is infused at a rate of 300-500 cc/hr. The infusion begins in the operating room as soon as the vascular anastomosis of the renal allograft has been completed. Protamine, 25 mg, is administered I.V. after completion of the first half of the bone marrow infusion. If a partial thromboplastin time measured after completion of the marrow infusion is > 60 seconds, the protamine treatment shall be repeated
Detailed Description:
The induction of transplantation tolerance involves the specific elimination of the immune response to the transplant but not to other antigens. In the realm of kidney transplantation, tolerance means that the recipient is unable to detect the donor transplant kidney as foreign, and therefore the recipient is unable to reject the kidney. Donor bone marrow engraftment leads to kidney graft tolerance in animal models. Renal failure is a major complication of multiple myeloma, a plasma cell malignancy for which the only known cure is allogeneic bone marrow transplantation. Standard bone marrow transplantation is associated with frequent toxicity in patients with multiple myeloma, and is generally no considered an option for those patients with end stage renal disease. Myeloma patients are excluded from conventional renal transplantation protocols because of their underlying malignancy. A less toxic bone marrow transplantation protocol, combined with renal transplantation, could provide an opportunity for cure of the myeloma and correction of ESRD in patients with this disease. In addition, successful marrow engraftment may be expected to lead to a state of tolerance. Successful implementation of tolerance would be a major benefit to transplant recipients. The significance of developing tolerance is that the patient would be spared the disabling complications of indefinite immunosuppression, which include infections, cataracts, osteoporosis, diabetes, atherosclerosis, hypertension, and malignancy
|Ages Eligible for Study:
|18 Years to 65 Years (Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Recipient Inclusion Criteria
- Participants with end-stage renal failure due to or in association with greater than or equal to stage II multiple myeloma
- Males or females 18 - 65 years of age.
- Participants must have an HLA-matched or one of six HLA A, B, or DR antigen-mismatched related donor, with high resolution molecular DR allele determination.
- Men and women of reproductive potential must agree to use a reliable method of birth control during the treatment, and women should do so for a period of 2 years following the transplant.
- Participants should be on dialysis or have a CrCl <20 ml/min.
- Participants must receive medical clearance by a cardiologist prior to conditioning for transplant.
- Life expectancy greater than or equal to 6 months.
- Recipient ability to understand and provide informed consent.
Recipient Exclusion Criteria:
- Evidence of active infection as defined by: a) clinical syndrome consistent with viral or bacterial infection (e.g., influenza, URI, UTI) or b) fever with a clinical site of infection identified, or c) microbiologically documented infection, including, but not limited to, bacteremia or septicemia.
- Participation in other investigational drug use at the time of enrollment.
- Contraindication to therapy with any one of the proposed agents (e.g., history of allergy to horse serum in ATG).
- Serologic positivity to HIV, HCV, or HbsAg positivity.
- Women of childbearing age in whom adequate contraception cannot be maintained.
- Malignancy within the past two years other than multiple myeloma, excluding basal cell carcinoma of the skin and carcinoma in situ of the cervix.
- AST/ALT > 3 x normal or bilirubin > 1.5 x normal (unless due to Gilbert's syndrome).
- Pregnancy or uncontrolled serious medical illness not related to underlying myeloma.
- Cardiac ejection fraction < 40% by echocardiogram; individual assessment if ejection fraction between 40% and 50%.
- FEV1 < 50% predicted or corrected DLCO < 50% predicted.
- ABO blood group incompatibility in the host-vs-graft direction.
Donor Inclusion Criteria:
- HLA-matched or one of six HLA A, B, or DR antigen-mismatched related male or female donor 18-65 years of age.
- ECOG performance status 0 or 1.
- Excellent health per conventional pre-donor history (medical and psychosocial evaluation).
- Acceptable laboratory parameters (hematology in normal or near-normal range; liver function < 2 times the upper limit of normal and normal creatinine).
- Compatible ABO blood group.
- Negative donor lymphocyte crossmatch.
- No positive testing for viral infection (HbsAg, HIV, HCV, HTLV-1).
- Cardiac/Pulmonary evaluation within normal limits (CXR, EKG).
- Donor ability to understand and provide informed consent.
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00854139
Please refer to this study by its ClinicalTrials.gov identifier: NCT00854139
|United States, Massachusetts
|Massachusetts General Hospital
|Boston, Massachusetts, United States, 02114
Sponsors and Collaborators
Massachusetts General Hospital
|Principal Investigator:
|Thomas R Spitzer, MD
|Massachusetts General Hospital
More Information
Keywords provided by Thomas Spitzer, Massachusetts General Hospital:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on September 20, 2017
|Responsible Party:
|Thomas Spitzer, MD, Massachusetts General Hospital
|ClinicalTrials.gov Identifier:
|NCT00854139 History of Changes
|Other Study ID Numbers:
|Study First Received:
|February 27, 2009
|Last Updated:
|April 13, 2015
Keywords provided by Thomas Spitzer, Massachusetts General Hospital:
Multiple myeloma
Renal failure
Kidney transplant
Additional relevant MeSH terms:
Multiple Myeloma
Neoplasms, Plasma Cell
Kidney Diseases
Kidney Failure, Chronic
Renal Insufficiency, Chronic
Neoplasms by Histologic Type
Hemostatic Disorders
Vascular Diseases
Cardiovascular Diseases
Blood Protein Disorders
Hematologic Diseases
Hemorrhagic Disorders
Lymphoproliferative Disorders
Immunoproliferative Disorders
Immune System Diseases
Urologic Diseases
Renal Insufficiency
Antilymphocyte Serum
Immunosuppressive Agents
Immunologic Factors
Physiological Effects of Drugs
Antirheumatic Agents
Antineoplastic Agents, Alkylating
Alkylating Agents
Molecular Mechanisms of Pharmacological Action
ClinicalTrials.gov processed this record on September 20, 2017


text:
What's so special about Cutline for SEO?
Chris Pearson has stuff all over his web pages and his hokey videos about how special his Cutline theme is for SEO. He even goes so far as to call it a "framework," as if it's more than just another theme, and changes WordPress into something fundamentally different. I don't get it. What specifically is so special about Cutline?
Viewing 3 replies - 1 through 3 (of 3 total)
Viewing 3 replies - 1 through 3 (of 3 total)
- The topic 'What's so special about Cutline for SEO?' is closed to new replies.


text:
Here's the trailer for the Sundance hit acquired by Fox Searchlight, with John Hawkes as a paralyzed man who is determined to lose his virginity. Helen Hunt and William H. Macy co-star. Screened at Sundance as The Surrogate and based on a true story, the movie written and directed by Ben Lewin is slated to open October 26th:
Hot Trailer: 'The Sessions'
Subscribe to Deadline Breaking News Alerts and keep your inbox happy
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What's Hot on Deadline
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text:
Managed by CALM Golf Inc.
Charlie Lanzetta, Master PGA Professional, New England PGA Hall Of Fame, U.S. Kids
Top 50 Instructor, & Certified Instructor
Goal: Our mission for this season is to encourage all women to come out and get involved with golf in some way or another. Whether it is playing a few holes with your friends, taking clinics, 9 hole mixed couples events or playing with your kids, we WANT to see you out there!
These clinics are designed to create a fun and exciting atmosphere while learning the fundamentals of golf. Ladies clinics are a great way to meet your fellow golfer, build friendships and develop strong skills that will last a lifetime.
1 hour on Saturday mornings for the month of September.
Whether you are a beginner, intermediate or advanced player these clinics are for you. Choose the time that works best for you and the class that you are interested in.
Time: 9:30-10:30 am
September 2 - Putting
September 9 - Chipping
September 16 - Pitching
September 23 - Full Swing
Fees: $20 Person/Class
Inclement Weather: Make-up classes will be scheduled based on availability.
Wait list: wait lists will be activated once a clinic/class is full.
Registration: Minimum of 4 max of 6 to run.
Clinic Cancellation Policy: Please cancel no less than 48 hours prior to the start of each clinic to allow for waitlist people to be contacted. Please cancel with Beth via email or by calling the golf shop.
Contact info:
Beth O'Kelly
PGA Golf Professional
Director of Instruction
Strawberry Valley Golf Course
Please email Beth to sign up for the Clinics or the golf shop at 781-347-4877


text:
Patients with chronic heart failure (HF) are characterized by disability and exercise intolerance which impair their quality of life and depict major source of morbidity in this population. Cardinal determinants of these characteristics include excessive exercise pressor reflex, premature fatigue, and exertional dyspnea. Abnormally elevated neural feedback from mechano- and/or metabosensitive group III and IV muscle afferents might play a key role in these abnormalities. However, even in healthy humans, our understanding of the exact role/relative contribution of group III/IV afferents to the circulatory and ventilatory control during exercise and the development of fatigue is incomplete. By studying both HF patients and age- and activity-matched healthy controls (CTRLs), we will evaluate the impact of HF on the relative contribution of these muscle afferents to a) the circulatory/ventilatory control, and b) the development of central and peripheral fatigue during exercise. Additionally, the proposed research will examine whether HF affects the expression of genes linked to metabosensitive receptors on muscle afferents and the functional impact of these changes in terms of central fatigue. Specifically, we will use lumbar intrathecal fentanyl to block the central projection of group III/IV muscle afferents during exercise (no concomitant effect on feedforward drive). This unique, previously proven approach will enable us to evaluate the effects of group III/IV muscle afferents on leg blood flow, heart rate, blood pressure and ventilation during large and small muscle mass rhythmic exercise (bicycle and single leg knee-extension), and the development of central and peripheral fatigue (using magnetic femoral nerve stimulation techniques). Furthermore, we will take baseline and post-exercise blood samples from HF patients and CTRLs to determine the expression (mRNA) of ASIC3, P2X, and TRPV1 metaboreceptors on leukocytes in each population. Finally, to determine the specific contribution of these metabosensitive molecular receptors to the development of central fatigue in HF patients and CTRLs, we will perform an intramuscular infusion of a "metabolite soup" into the unfatigued quadriceps muscle. We have designed the "soup" to exclusively activate ASIC3, P2X, and TRPV1 metaboreceptors and have previously verified its specificity in published animal and human studies. Based on recent findings suggesting blunted metaboreceptor sensitivity in HF patients vs. CTRLs, we expect, following the specific stimulation of metaboreceptors due to the intramuscular soup infusion, greater central fatigue in CTRLs vs HF patients. The results from this analysis will contribute to a better understanding of the role of metaboreceptors as a potential mechanism underlying central fatigue and reflex abnormalities characterizing exercising HF patients. Combined, this research will provide new insight into the impact of HF on neural feedback and its role in the control of circulation and ventilation and the development of fatigue during physical activity. Furthermore, our experiments will identify potential molecular targets for therapeutic interventions with the overall purpose to improve the quality of life in patients with HF.
This research in humans with heart failure will provide new information on the mechanisms accounting for the altered blood flow, excessive blood pressure, severe breathlessness and high fatigability/ premature fatigue characterizing these patients during physical activity. These limitations not only cause disability, but also account for the hig mortality in this population. We will focus on the role of nerves originating in working limb muscles in determining these abnormalities. The results from our research will identify potential targets for therapeutic interventions, with the overall purpose of improving the quality of life of patients with heart failure.
|Taylor, Janet L; Amann, Markus; Duchateau, Jacques et al. (2016) Neural Contributions to Muscle Fatigue: From the Brain to the Muscle and Back Again. Med Sci Sports Exerc 48:2294-2306
|Blain, Gregory M; Mangum, Tyler S; Sidhu, Simranjit K et al. (2016) Group III/IV muscle afferents limit the intramuscular metabolic perturbation during whole body exercise in humans. J Physiol 594:5303-15
|Ives, Stephen J; Amann, Markus; Venturelli, Massimo et al. (2016) The Mechanoreflex and Hemodynamic Response to Passive Leg Movement in Heart Failure. Med Sci Sports Exerc 48:368-76
|Sidhu, Simranjit K; Weavil, Joshua C; Venturelli, Massimo et al. (2015) Aging alters muscle reflex control of autonomic cardiovascular responses to rhythmic contractions in humans. Am J Physiol Heart Circ Physiol 309:H1479-89
|Amann, Markus; Sidhu, Simranjit K; Weavil, Joshua C et al. (2015) Autonomic responses to exercise: group III/IV muscle afferents and fatigue. Auton Neurosci 188:19-23
|Rossman, Matthew J; Trinity, Joel D; Garten, Ryan S et al. (2015) Oral antioxidants improve leg blood flow during exercise in patients with chronic obstructive pulmonary disease. Am J Physiol Heart Circ Physiol 309:H977-85
|Weavil, J C; Sidhu, S K; Mangum, T S et al. (2015) Intensity-dependent alterations in the excitability of cortical and spinal projections to the knee extensors during isometric and locomotor exercise. Am J Physiol Regul Integr Comp Physiol 308:R998-1007
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Showing the most recent 10 out of 21 publications


text:
Claude Denson Pepper
Claude Denson Pepper was an American politician of the Democratic Party, and a spokesman for left-liberalism and the elderly. In foreign policy he shifted from pro-Soviet in the 1940s to anti-Communist in the 1950s. He represented Florida in the United States Senate from November 4, 1936, to January 3, 1951, and the Miami area in the United States House of Representatives from January 3, 1963, to May 30, 1989. Wikipedia*
On the C-SPAN Networks:
Claude Denson Pepper has 72 videos in the C-SPAN Video Library; the first appearance was a 1979 House Proceeding as a Democratic Representative for Florida's 14th district. The year with the most videos was 1988 with 26 videos. Most appearances with Mary Rose Oakar (2), Leo McCarthy (2), Sala Galant Burton (2). Most common tag: Democratic National Convention.


text:
|Publication number
|Publication type
|Application number
|Publication date
|Mar 3, 1987
|Filing date
|Mar 6, 1985
|Priority date
|Mar 18, 1981
|Fee status
|Also published as
|Publication number
|Manfred Ruedle, Kurt Stoll
|Original Assignee
|Manfred Ruedle, Kurt Stoll
|Export Citation
|BiBTeX, EndNote, RefMan
|Patent Citations (20), Referenced by (25), Classifications (15), Legal Events (5)
|External Links: USPTO, USPTO Assignment, Espacenet
This is a continuation of application Ser. No. 357,015, filed Mar. 11, 1982, now U.S. Pat. No. 4,524,803.
The present invention relates to a servo spool or shear action valve and, more particularly, to such a valve having a valve housing with a ported spool hole and a spool movable in the hole between at least two positions, the spool having fluid control collars for acting with the ports, and with a servo piston system for moving the valve spool in two directions and at least one remotely controlled pilot valve for causing the servo piston system to be put under and freed of pressure.
Such servo valves are used in a number of different forms. Representative uses for such valves are to be seen in compressed air and hydraulic circuits for motor vehicles, more specially trucks. For such purposes the servo valves have to be produced in generally small production runs with different design details, as for example for working pressures of 10 to 16 bar. One shortcoming of known servo valves is that it is hard to make small production runs of customized valves at low prices. A further point is that, if for some reason or other the holes for fixing the valves in place and the screws or the like for this purpose are to be placed nearer to each other, there will be the further shortcoming that the valves have to be made smaller in size, this cutting down the rate of flow therethrough, that is to say the size of the ducts for the controlled fluid.
For this reason, one purpose of the present invention is that of designing a valve system of the sort in question here in which, while decreasing the distance between the holes for fixing the valve in place, the cross-section of ducts through the valve, important for the rate of flow through the valve, is kept unchanged.
For effecting this purpose, and further purposes, in the invention the control ports in the housing are placed in valve liners which are spaced axially and are symmetric with respect to a middle plane through the housing; the working spaces for the servo piston system are within the valve spool hole within the valve liners; and the valve housing has at least one body shut off at its ends by end plates, of which at least one end plate has an air let-off hole with a large size in cross-section.
With respect to effecting further purposes of the invention, the through-holes for fixing parts such as screws, used for fixing the valve in position, are designed to extend through a middle hole for air running through the body to a greater or lesser degree, each screw or the like having a sealing washer, for example in the form of an O-ring placed between a support shoulder and the lower face of the head of the screw or the like.
The servo spool valve of the present invention has a highly modular design so that the separate parts may be readily changed over for customizing the design, it being possible, for example, to make the liners of metal for high pressure uses whereas for lower pressures valve liners of synthetic resin may be used. In this case, different sealing rings will be used on the control collars of the valve spool. Valve liners of high-impact resin such as polymethyl oxide with sealing rings of polyurethane may be used. For higher pressures valve liners of aluminum, for example, may be used. Another point is that it becomes possible to make use of large sizes of inner parts to get a high rate of flow, even although the distance between the bolts or the like and their holes is decreased. Even with the screws placed so near each other as to be cutting through the middle liner hole of the valve, the size of the cross-section for flow of the fluid is as large as in the prior art, because of the washers being designed and placed in a certain way so that there is no chance of loss of pressure fluid from the inner space or hole in the middle of the valve through the screw holes.
The body of the servo valve of the present invention may be made from a metal section cut off to the desired length, this greatly cutting down the amount of machining needed. Furthermore, no high-price injection casting molds are needed for producing the valve body.
Because an air let-off valve is directly placed within one of the end plates of the valve housing, air is let off very quickly from the servo piston adjacent thereto. For this reason, there are short cycle times.
Further useful developments of the invention will be seen in the claims.
As part of one possible further development of the invention, the air let-off valve has a valve jumper with an axial stem for use with a valve seat, while the edge of the jumper has a U-like cup. An opening joined up with the servo piston space is joined up with the part of the space for the valve which is between the valve jumper and the air let-off valve seat. Such a design, while being very simple mechanically, can be used for effecting the two purposes of controlling the inlet of fluid under pressure and letting off such fluid to and from the servo piston.
It is furthermore possible for the body of the valve to have two fluidwise separate, parallel connection ducts running along the housing, and two groups of connection ports for two pilot valves, some of the pilot valve connection ports being joined up together by a further duct in the housing, and the two connection ducts each opening at a respective one of the two end faces of the valve housing. With this further development of the invention it is possible to make certain that, using the same valve components, it is possible to make up a normal servo valve (using one pilot valve) and a pulse valve (using two pilot valves).
A further development of the invention is characterized in that through-holes for valve fixing parts such as bolts or screws extend through a hole in the housing having the valve liners within it, a gasket placed at the connection ports of the valve running out past the through-hole, and in that, at the opposite end of the through-holes, there are seals which, upon tightening of the screws or bolts, make a tight seal between the head of the screw in question and the valve body.
Such a design makes possible the use of large diameter screws or other fixing parts which are able to take up high forces while nevertheless keeping the valve housing small in size.
Furthermore, one of the servo pistons may be formed by one end face of the valve slide while the second servo piston is housed in a blind hole in the valve spool, such blind hole being joined up with the high pressure connection port of the valve at all times.
As part of a still further development of the invention, two servo pistons are placed in the valve spool so that they may put under pressure separately, such pistons having springs for forcing them into outwardly moved positions. With this further design, it is possible to get a third working position of the spool valve, that is to say a neutral or middle position. Such a three-position valve may be made up, to a high degree, of components used for producing two-position valves.
The valve liners may have pressure balancing cutouts, at least at the limit of one of their control ports, so that the seals on the valve spool are pressure-balanced every time they are moved over the limit of a control port.
It is furthermore possible for the valve liners each to be made up of two liner pieces, one of such liner pieces having spacer fingers running out axially past an end thereof for fixing the size of one of the control ports. This further development of the invention gives a useful effect with respect to producing a valve liner by injection molding, particularly if one of the control ports has pressure-balancing cutouts and the parting plane is placed between the two liner pieces running through this control port.
As a further development of the invention, the walls of metal between the pressure-balancing cutouts have inner rounded corners, this making it possible for the separate sealing rings to be pressure-balanced, it being unimportant on which side of the control port they are located.
For use with high pressures, the spool may have piston rings forced outwards against the inner faces of the liners by rings of elastic material.
An account will now be given of the invention using the working examples to be seen in the figures.
FIG. 1 is an axial section through a 5 port, 2 position servo valve.
FIG. 2 is a cross-section through the valve of FIG. 1 on the section line II--II marked in FIG. 1.
FIG. 3 is an axial section through a somewhat changed form of a 5 port, 2 position servo valve.
FIG. 4 is a section through a further 5 port, 3 position servo valve made up of parts as used in the valve of FIG. 3.
FIG. 5 is a view of a changed form of a valve liner used in the valve of FIG. 4.
FIG. 6 is an end-on view of the right hand end of the liner of FIG. 5.
FIG. 7 is a view on a greater scale of the portion, marked as VII in FIG. 5, of the valve liner.
FIG. 8 is a view on a greater scale of the portion, marked as VIII in FIG. 6, of the valve liner.
In FIG. 1 the reader will see a valve support plate 10 with a high pressure connection or control port 12, two low pressure connection or control ports 14 and 16 and two working connection or control ports 18 and 20. Furthermore, on valve support plate 10 there is a gasket 22 which is made of rubber-like material which has openings P,R,S,A1 and A2 therethrough lined up with connection ports 12 to 20. On gasket 22 there is seated a 5 port, 2 position valve, generally numbered 24 which has a solenoid pilot valve 26 thereon. The valve unit, made up of the spool valve 24 and the pilot valve 26, is screwed onto support plate plate 10 by bolts 28 (see furthermore FIG. 2.)
Spool or shear action valve 24 has a housing which includes a body 30, shut off at its two ends by end plates 32, 34. Valve body 30 has a middle air hole 36 running therethrough, this hole having halfway between its ends an inwardly running shoulder 38 acting as a stop on the left and the right for two valve liners 40 and 42, which are the same in all details so that the account now to be given is limited to liner 42. Liner 42 is gas-tightly joined up with shoulder 38 by an O-ring 44, while a gas-tight joint between liner 42 and the wall of the hole 36 is produced by an O-ring 46, the other end of liner 42 being sealed with respect to end plate 34 by an O-ring 48. Valve liner 42 has two broad grooves 50 and 52 in its outer face joined up by way of connection openings 54 and 56 (with an equal angle between them) with a spool hole 58 within the sleeve-like valve liner 42.
A valve spool 60, freely running through the spool hole 58 of the two valve liners 40 and 42, has collars 62 at its ends with annular grooves in which O-rings 64 are seated. Collars 66 and 68 of valve spool 60, in each case, have O-rings 70, 72 provided in annular grooves, whose axial spacing is somewhat greater than the axial length of connection openings or ports 54, 56. The collars 62, 66 and 68 have the function of walling off and ending fluid control grooves 74, 76 and 78 on spool 60, such grooves producing the desired connections between the working connection ports 18 and 20, as may be desired, and the high-pressure connection port 12 or the adjacent port of the low-pressure connection ports 14 and 16.
The valve spool 60 takes the form of a hollow piston, whose inner stepped blind hole 80 is joined up at all times by way of a radial connection port 82 in the outer wall of valve spool 60 with the high-pressure connection port 12. In the part of the hole 80 seen on the right in FIG. 1, a piston is placed, made up of a piston head 84 with a U-cup packing 86. Piston head 84 has a stem 88 running up against end plate 34. In this way, valve spool 60 is, at all times acted upon by a force produced by the pressure of the working fluid, and gives a tendency of pushing the spool into the position of FIG. 1, that is to say in which the high-pressure connection port 12 is joined up with the working connection port 18, whereas the working connection port 20 is joined up by way of fluid control groove 78 with the low-pressure connection port 16.
The high-pressure connection port 12 is furthermore joined up by way of a duct 90 in the housing with the inlect duct 92 of the pilot valve 26, whose moving valve part 94 may be pulled clear of a valve seat 95 at the end of the inlet duct 92 by a solenoid (not to be seen in detail), so that a connection is produced with an outlet duct 96 of pilot valve 26, duct 96 joining up with the generally axial connection duct 97 in housing body 30. Duct 97 is joined up at the end face of body 30 with an aligned inlet duct 98 in the end plate 32, which extends to a valve space 100 formed in the end plate 32. Within valve space 100, there is a valve seat 102 producing a valve function with the middle part 104 of a valve member of valve jumper 106, whose outer edge is formed as a U-cup packing 108, jumper 106 forming a check valve system.
The space to be seen in FIG. 1 under the jumper 106 and over the valve seat 102 is joined up by way of a port 110 with the left hand end, as seen in FIG. 1, of the valve spool hole 58 of valve liner 40.
At its outlet end, valve seat 102 has a muffler 112 rested on a fixing or retaining ring 114.
The spool hole 58 within liner 42 is joined up with an air let-off hole 116 in the end plate 34 having a filter 118 within it.
An account will now be given of the operation of this servo valve.
If the solenoid pilot valve 26 is not turned on electrically, valve spool 60 will be kept in the first position, to be seen in FIG. 1 and, on turning on solenoid valve 26, the left hand end of valve spool 60 will be acted upon by pressure, cup-like packing 108 of jumper 106 being pushed back out of the way by the pressure. Valve spool 60 will now be moved to the right because of the differential pressure effect on it, that is to say to the right as the valve is seen in FIG. 1, the right hand end of the spool then coming up against the end plate 34. In this working position, the high-pressure connection port 12 is joined up with the working connection port 20 while the working connection port 18 is joined with the low-pressure port 14. On turning off solenoid pilot valve 26, the pressure in inlet duct 92 will go down, jumper 106 then whipping upwards and pressure being let off from the left hand end face of valve spool 60 by way of valve seat 102 and muffler 112, spool 60 then running over to its left hand position (FIG. 1) at a high speed, because the let-off valve (parts 102, 106) is made a part of end plate 32 itself and the letting off of the compressed air takes place through openings which are large in cross-section and small in length.
As the reader will see from FIG. 2, the through-holes 120 in the valve body 30 for taking up bolts 28 are designed cutting through the air hole 36 in the valve body, this making it possible for large diameter bolts 28 to be used without (overly) increasing the width of the valve body 30. For sealing off the through-holes 120, use is made on the support plate side of gasket 22 while the top ends, seen in FIG. 2, of through-holes 120 are sealed off by elastic washers 122, each taken up in a washer groove 124. Such groove is at the lower end of a pocket 126 in which the head 128 of the bolt 28 is placed. Head 128 is forced against the floor of pocket 126 after tightening bolt 28 so that gasket 122 is forced together to a given degree as designed for, no more, no less.
The 5 port, 2-position servo valve of FIG. 3 is by and large very much like that to be seen in FIGS. 1 and 2, like parts being marked with the same part numbers.
The servo valve of FIG. 3 is different to that of FIGS. 1 and 2 in that the O-rings 64, 70, 72 of valve spool 60 are not placed running directly on liners 40, 42 in spool holes 58 and, in fact, such rings are used for radially elastically forcing outwards piston rings 130 made of PTFE (Teflon).
Furthermore, there is a pilot inlet duct 132 running in the length-direction of the body 30 and communicating with two housing ducts 90a and 90b, which are placed symmetrically with respect to the middle plane of the body 30, such ducts 90a and 90b taking over the function of the housing duct 90 in FIG. 1. Furthermore, there are two end parts 134a and 134b of two connection ducts 97a and 97b running parallel to each other in the length-direction of the housing, the end parts 134a and 134b running crosswise through the body and symmetrically with respect to its middle plane. Connection duct 97a comes to an end in the end face on the left in FIG. 3 of body 30, while connection duct 97b comes to an end at the right hand end face of body 30.
The housing duct 90b is shut off air-tightly by a cover plate 136 using a screw 138 in body 30 and an O-ring 140. Duct part 134a is air-tightly sealed off by way of an O-ring 142 with respect to cover plate 136 and is joined up with the outside atmosphere by a filter body 144 and an opening 148, lined up with the filter body, in cover plate 136.
The workings of the servo valve of FIG. 3 are generally the same as those of the valve of FIG. 1, but in the valve of FIG. 3 there is an air let-off hole 116' joining up with the end of connection duct 97a so that using generally the same standard parts for the pilot valve 26, the valve body 30, the end plate 32, 34 and the rest of the parts of the valve, it is possible to make 5 port servo valves with 2 and 3 working positions, only some small changes in valve spool 60 being needed.
FIG. 4 is a view of a servo valve which is very much the same as that of FIG. 3 but, furthermore, has a middle position.
In the servo valve of FIG. 4, there are, on the one hand, two end plates 34a and 34b, each having a high speed air let-off valve as detailed in connection with FIG. 1. Furthermore, cover plate 136 has been unscrewed and taken off and its place taken by a second solenoid pilot valve 26b.
Valve spool 60 no longer has the connection port 82: two piston bodies 84a and 84b are symmetrically placed in the spool which are acted upon by helical compression springs 150a and 150b so that they have the tendency of moving axially outwards. Circlips 152a and 152b are used to keep piston bodies 84a and 84b within the valve spool 60.
An account will now be given of the operation of the valve of FIG. 4.
If the two solenoid pilot valves 26a and 26b are turned off, the piston bodies 84a and 84b are freed of pressure, the valve spool 60 being then pushed by helical compression springs 150a and 150b into the middle position, see FIG. 4.
On solenoid pilot valve 26a being turned on, by way of connection duct 97b and end plate 34b, the right hand end face of valve spool 60 will be acted upon by pressure, the spool then moving to the left in FIG. 4, that is to say moving into a first working position in which the working port A1 is joined up with the pressure connection P and the working port A2 is joined up with the low-pressure port S.
If, oppositely, solenoid pilot valve 26b is turned on, the left hand end face of the valve spool 60 will be acted upon by pressure by way of connection duct 97a and the end plate 34a so that the valve spool 60 will be moved to the right in FIG. 4; in this second working position, the working port A1 is joined up with the low-pressure port R and the working port A2 is joined up with the pressure port P.
If the two solenoid pilot valves 26a and 26b are turned on at the same time, the valve spool 60 will again be acted upon by balanced forces, that is to say it will be pushed into a middle position by the two helical compression springs 150a and 150b.
A somewhat different form of valve liner 40' will be seen in FIG. 5, which may be used to take the place of valve liners 40 and 42. Parts of the valve liner which are the same as the parts noted earlier have the same part numbers so that no new account is given thereof.
Valve liner 40' is made up of two liner pieces 154 and 156, liner piece 154 having connection ports 56 with the function of a fluid control port. Furthermore, liner piece 154 has outer grooves for the different sealing rings resting against the inner wall of the valve body 30, such grooves having lips 158 on their floors, as may be seen in section, so that the O-rings are kept in position without any chance of them being twisted. Liner piece 154 has, at its right end (right in the sense of FIG. 5) a number of pressure-balancing cutouts 160, the pieces of material therebetween being rounded off at 162 near the inner face of the hole 58, as may be more specially seen in FIG. 7. On the same lines the liner piece 156 has, at its side turned towards liner piece 154, pressure-balancing cutouts 164, the pieces of material or teeth therebetween being rounded off or radiussed in the inside as well. Liner piece 156 has an axially open groove-like pocket 166 for an O-ring such as ring 44 (FIG. 1).
The right hand end (FIG. 5) of liner piece 154 has three spacing fingers 168 so that liner piece 156 may not be rested completely flatly against liner piece 154 and, in fact, a space is kept between the two liners 154 and 156 with the connection ports 54 defined therebetween, such ports 54 functioning as fluid control ports for use with the control collars of valve spool 60. As may be seen from the figure, the spacer fingers 168 are lined up axially with untoothed pieces of material between the connection ports 56. With respect to the function, the breadth of the connection ports 54 may be seen to be dependent on the axial size of the spacer fingers 168 with the addition of the sum of the depth of the balancing cutouts 166, 164.
As may be seen from the spacer fingers 168 on the lower right in FIG. 5, the inner face of such fingers is out of line in a radially outward direction with respect to the valve spool hole 58 so that the sealing ring units (in FIG. 1: 70, 72; in FIGS. 3 and 4: 70, 130, 73, 130) supported on the control collars of the valve spool may become wider in a radial direction when they are moved across the space between the inlet pieces 154 and 156.
FIG. 7 is a view on a greater scale of one of the pressure-balancing cutouts 160 and one of the rounded-off structures 162. In addition, the reader will see a part of control collar 66 with O-ring 70, the position of the valve spool being such that the O-ring 70 is still resting full against the inner face of the liner spool hole 58 and it will be seen that O-ring 70 is greatly forced together. This is made clear further by the rough view on the right of FIG. 7 in broken lines to make clear the condition of the O-ring 70 after it has been moved past the limit of the control port. It will be seen that the rounded structure 162 makes it more readily possible for the O-ring 70 to be moved backwards and forwards over the limit of the control part so that wear is cut down. A further point is that the groove with the O-ring 70 therein is joined up with the outside when the O-ring 70 is put under pressure and freed of pressure, by way of pressure-balancing cutouts 160, so that not only on moving the valve spool 60 to the right, but furthermore on moving it to the left, pressures will be balanced at the O-ring 70 when it is moved past the limit of the control port.
As may be seen from FIG. 8, the teeth or walls between the pressure-balancing cutouts 160 may be seen to be rounded off at their radially inner corners parallel to the spool axis at 170, this, as well, making it more readily possible for the O-rings to be moved across the limits of the control ports.
|Cited Patent
|Filing date
|Publication date
|Apr 15, 1953
|Nov 10, 1959
|Clarence Johnson
|Pilot operated four-way valve
|Dec 13, 1962
|Jun 29, 1965
|Parker Hannifin Corp
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|Impulse valve
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|Kurt Stoll
|Spool valve
|Jan 7, 1977
|Jul 28, 1977
|Crouzet Sa
|Bistabiles pneumatisches relais
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|Mar 16, 1994
|Jun 6, 1995
|Yamada T.S. Co., Ltd.
|Spool type valve
|Aug 30, 1995
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|Smc Corporation
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|Mar 25, 2005
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|L'air Liquide, Societe Anonyme A Directoire Et Conseil De Surveillance Pour L'etude Et L'exploitation Des Procedes Georges Claude
|Fluid distribution and control valve and use thereof to supply enriched air to the occupants of an aircraft
|May 17, 2006
|Jan 19, 2010
|Westlock Control Corporation
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|U.S. Classification
|137/625.64, 251/900, 137/625.66, 137/625.69
|International Classification
|Cooperative Classification
|European Classification
|Aug 13, 1990
|Fee payment
Year of fee payment: 4
|Aug 15, 1994
|Fee payment
Year of fee payment: 8
|Sep 22, 1998
|Maintenance fee reminder mailed
|Feb 28, 1999
|Lapse for failure to pay maintenance fees
|May 11, 1999
|Expired due to failure to pay maintenance fee
Effective date: 19990303


text:
Pelican Mitylite 2440 Photoluminescent Body LED Flashlight
Product Details
The ideal compact emergency flashlight during a blackout comes standard in our 2480 Emergency Lighting Station. The 2440PLB has a tough resin body that emits a bright glow in the dark. The new generation photoluminescent material in the plastic absorbs the energy from any light source, even fluorescent lights. Use the 5-LED cluster, powered by 4 AA alkaline cells (included), to light your way to safety. The MityLite™ 2440PLB comes with a tail switch for easy, one hand operation.
Tech Specs
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|Zoro #: G2197684 Mfr #: 1436-012
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Many car makers offer automatic emergency-braking systems on some models or not at all, but that's about to change.
Twenty automakers have just committed to making the life-saving feature standard in the coming years. This new commitment by automakers is really good news for everyone.
And as a result of this move to make automatic emergency braking systems standard, Consumer Reports is even changing its car rating system.
Mike and Linda Hanson were driving for hours on the highway when Mike says he zoned out.
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Consumer Reports tests these advanced safety features that use a laser, radar or camera to anticipate a frontal crash.
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"We would have been at the very least seriously injured, probably killed," says Mike.
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Consumer Reports has changed its car rating system, giving bonus points to vehicles that include this safety technology standard on all its trim lines.
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To view a list of cars with advanced safety features, CLICK HERE.
For more information on the automatic emergency braking standard, visit the Consumer Reports website.
Consumer Reports: Automatic emergency brake systems
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The Exchange Rate and Macroeconomic Policy: Changing Postwar Perceptions
- McKinnon, Ronald I
No abstract is available for this item.
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Volume (Year): 19 (1981)
Issue (Month): 2 (June)
Pages: 531-557
|Contact details of provider:
| Web page: https://www.aeaweb.org/journal
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Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
Cited by:
- Maurice Obstfeld, 2001.
"International Macroeconomics: Beyond the Mundell-Fleming Model,"
NBER Working Papers
8369, National Bureau of Economic Research, Inc.
- Maurice Obstfeld., 2001. "International Macroeconomics: Beyond the Mundell-Fleming Model," Center for International and Development Economics Research (CIDER) Working Papers C01-121, University of California at Berkeley.
- Obstfeld, Maurice, 2001. "International Macroeconomics: Beyond the Mundell-Fleming Model," Center for International and Development Economics Research, Working Paper Series qt6796n8s0, Center for International and Development Economics Research, Institute for Business and Economic Research, UC Berkeley.
- Maurice Obstfeld, 2003. "International Macroeconomics: Beyond the Mundell-Fleming Model," International Finance 0303006, EconWPA.
- Alexis Cruz-Rodriguez, 2013. "Choosing and Assessing Exchange Rate Regimes: a Survey of the Literature," Revista de Analisis Economico – Economic Analysis Review, Ilades-Georgetown University, Universidad Alberto Hurtado/School of Economics and Bussines, vol. 28(2), pages 37-61, October.
- Cruz Rodriguez, Alexis, 2009. "Choosing and assessing exchange rate regimes: A survey of the literature," MPRA Paper 16314, University Library of Munich, Germany.
- Frank Agbola & Chartri Kunanopparat, 2005. "Determinants of exchange rate practices: some empirical evidence from Thailand," Applied Economics, Taylor & Francis Journals, vol. 37(7), pages 807-816.
- Jürgen von Hagen & Jizhong Zhou, 2005. "The choice of exchange rate regime: "An empirical analysis for transition economies" ," The Economics of Transition, The European Bank for Reconstruction and Development, vol. 13(4), pages 679-703, October.
- von Hagen, Jürgen & Zhou, Jizhong, 2002. "The choice of exchange rate regimes: An empirical analysis for transition economies," ZEI Working Papers B 03-2002, University of Bonn, ZEI - Center for European Integration Studies.
- von Hagen, Jürgen & Zhou, Jizhong, 2002. "The Choice of Exchange Rate Regimes: An Empirical Analysis for Transition Economies," CEPR Discussion Papers 3289, C.E.P.R. Discussion Papers.
- von Hagen, Jurgen & Zhou, Jizhong, 2007. "The choice of exchange rate regimes in developing countries: A multinomial panel analysis," Journal of International Money and Finance, Elsevier, vol. 26(7), pages 1071-1094, November.
- von Hagen, Jürgen & Zhou, Jizhong, 2004. "The Choice of Exchange Rate Regime in Developing Countries: A Multinational Panel Analysis," CEPR Discussion Papers 4227, C.E.P.R. Discussion Papers.
- H.W. Arndt, 1998. "Globalisation," BNL Quarterly Review, Banca Nazionale del Lavoro, vol. 51(204), pages 73-89.
- Tarlok Singh, 2007. "Intertemporal Optimizing Models Of Trade And Current Account Balance: A Survey," Journal of Economic Surveys, Wiley Blackwell, vol. 21(1), pages 25-64, 02.
- Ramon Moreno, 1988. "Saving, investment, and the U.S. external balance," Economic Review, Federal Reserve Bank of San Francisco, issue Fall, pages 3-17.
- von Hagen, Jürgen & Zhou, Jizhong, 2004. "The choice of exchange rate regimes in developing countries: A mulitnominal panal analysis," ZEI Working Papers B 32-2004, University of Bonn, ZEI - Center for European Integration Studies.
- H.W. Arndt, 1998. "Globalisation," Banca Nazionale del Lavoro Quarterly Review, Banca Nazionale del Lavoro, vol. 51(204), pages 73-89.
- Meller, Patricio, 1987. "Review of the theoretical approaches to external adjustment and their relevance for Latin America," Revista CEPAL, Naciones Unidas Comisión Económica para América Latina y el Caribe (CEPAL), August.
- Chalfant, James A. & Love, H. Alan & Rausser, Gordon C. & Stamoulis, Kostas G., 1986. "The effects of monetary policy on U.S. agriculture," Department of Agricultural & Resource Economics, UC Berkeley, Working Paper Series qt1rn3z1wd, Department of Agricultural & Resource Economics, UC Berkeley.
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LBSU Track & Field Hosts Successful Beach Invitational
49ers continue to post top marks
49er Track & Field Competes on Second Day of Mt. SAC Relays
Jasmine Askew ran a lifetime-best in the 400m
LBSU Men's Track & Field Wins Sixth-Straight Big West Challenge Cup
49er men take first, women place second
Fifteen 49ers Named to MPSF Indoor Track & Field All-Academic Team
Eleven men, four women garner all-academic recognition
49er Men Finish Second, Women Place Sixth at Cal-Nevada Championships
LBSU posts four individual victories on Saturday
2012: NCAA West Preliminary qualifier in the 800m (36th) ... Placed fourth overall at the Big West Championships ... Ran a season-best 1:49.41 for a top-five performance at the Steve Scott Invitational ... That mark ranks sixth in school history ... Earned All-Big West honors as a member of the conference's second-place 4x400 relay team ... Also registered a season-best 3:54.07 in the 1500m at the Stanford Invitational ... Competed primarily in the 800m during the indoor season ... Finished 11th at the MPSF Championships ... Established the fourth-fastest 800m time (1:52.12) and fifth-fastest mile time (4:15.49) in indoor program history.
Cerritos College: Competed two years on the track and cross country teams at Cerritos College ... Led the Falcons to a runner-up finish at the state championships in 2011 ... Was the state champion in the 1500m as the Falcons took third in 2010 ... Finished 22nd at the 2010 SoCal Cross Country Championships.
High School: Four-year letterwinner in both cross country and track at John F. Kennedy High School.
Personal: Member of the 49er cross country team ... Majoring in English education.
Sport Links
- Recruits
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- Women's Track & Field Questionnaire
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- Cory Loebl - Throws
Media Guides
Front CoverFont Cover
Section 1Introduction
Section 2Coaching Staff
Section 3Meet the Men's Team
Section 4Meet the Women's Team
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Section 6History & Records
Back CoverBack Cover and Schedule
More Headlines
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In his first-ever NCAA Division I Outdoor Track and Field Championship appearance, junior Vincent...
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Long Beach State Continues Competition on Day 2...05/26/2017 - Track & Field
The Long Beach State track and field team continued its action on the second day of the NCAA West...


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Exciting news for Spotify users!
Listen up! Spotify is now available for Messenger, meaning you can say "Hello†to your friends…or "Sorry†if needed. We're making it easy for you to let your friends know what music you are loving at any moment. While chatting, tap the More tab and then choose Spotify to get started. Or if a friend sends you a song, just tap "Open†to hop over to Spotify to start listening.
This is rolling out today and will be available broadly soon!
This is the Facebook post made by the Messenger team.
This also indicates that Facebook is going different ways with WhatsApp and Messenger. Both have a lot (!!!) of users but both have some different principles. WhatsApp is dedicated to be as simple as possible while Messenger is dedicated to make conversations more feature rich. I can't image that WhatsApp will get Spotify support too, because this is against this principles.
Nevertheless have fun with this new feature and enjoy sending music to your friends!


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'12 Years a Slave' Wins Best Adapted Screenplay
FOX Searchlight
Writer John Ridley won the Academy Award for Best Adapted Screenplay for 12 Years a Slave. It's hard to think of any other nominee that could have taken the award besides the gripping adaptation of Solomon Northrop's memoir. Ridley, of Undercover Brother fame, adapted Northrup's real-life story of imprisonment slavery into a vivid study of battered humanity that shattered audiences and critics alike. Thanks to Ridley's assured script, 12 Years a Slave was given a raw emotive power that went hand in hand with Steve McQueen's direction.
The original 19th century memoir, which saw little play outside of history classrooms, is now among the exclusive community of Hollywood's awarded screenplays. In his speech, Ridley naturally thanked Solomon Northrup, whose searing account inspired the film. He also thanked the producers of the film.