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| When There is Not So Much Time Left |
Assalamualaikum, well currently I'm really busy with my studies especially in completing all my requirements for this year. I'll will seat for 2 papers this year and i have to finish all the requirements in each subject so that I can sit for the exam.
I had finish my requirement for Oral Surgery, just want to complete one more competency test. Maybe by this week or next I'll be able to complete it. What makes it difficult for me to sit for the exam is the requirement for community. I'm still far behind and I don't even have enough patient. I have 3 weeks left and I'm rushing to finish the requirements as soon as possible. Wish me luck.
So, same goes with my seniors. They also have to finish all their requirements in order to sit for their final exam before they can graduate and have the title Dr in front of their name. I hope they all can make it. They are our 1st batch it dental faculty if UiTM and they will present the greatness of our faculty, so I really hope they all can graduate!
Having so much requirements in not so much times is difficult. We have to use our lunch hour and after class to finish all the lab works. We have to do all the lab works by ourselves. That's the art of dentistry. So, most of the time we hanging out in the prostho lab and plaster room. Every day we go there, during lunch hour, 5pm - 7pm, even on saturday just for 1 main reason, finishing all our works. Although it just a tiny place but it is a place where we share a lot of things, where we learn something new. I'm glad to have very nice technicians that always be there for help us. They are very supportive and even used their time to help us.
These are some pictures of our prostho lab and plaster room..It's a bit messy, but that's why it is called plaster room..:)


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Coorg has become extremely popular among travellers in past few years. Coorg is known for its hospitality, bravery of its people and beautiful scenery. Coorg is admired as the 'Scotland of India' and also renowned as 'Kashmir of the South' for it's eye feasting scenic beauty. Nestled among the lusting greeneries of the Western Ghats, Coorg has a lot to offer. Misty hills, lush valleys and waterfalls, evergreen forests, endless mountain ranges, acres of coffee plantation, orange groves, cardamom, pepper plants and exotic villages make Coorg a one of the most beautiful hill stations you can visit in India.
Kodagu is the smallest district of Karnataka state with unique customs, distinct culture and traditions. The word Kodagu is derived from Kannada word Kodaimalenadu, which means 'dense forest on a steep hill'. Kodagu is called by the anglicised name of Coorg. People of Kodagu/Coorg are called as Kodavas or Coorgies. Coorg situated between 900 and 1525 m above sea level occupies 4,100km² in the Western Ghats an UNESCO world heritage site and one of the world's eight hotspots of biological diversity.
History of Coorg dates way back to as early as 888 AD. South Indian dynasties of the Gangas, the Kadambas, the Chalukyas, the Cholas, the Hoysalas, the Rastrakutas, the Vijaynagar Rayas and the Mysore Wodeyars ruled over Kodagu. Kodavas known as brave warriors and from Indian warrior caste, Kodagu did not had indigenous rulers. The Haleri dynasty was the last noteworthy dynasty in the history of Kodagu, which ruled the entire region of Kodagu for 234 years.
Coorg district is beautiful with scattered 291 villages and with a 5 urban centers. Coorg had a population of 5,54,762 as of 2011 census. Madikeri or Mercara town is the district headquaters of Coorg. Coorg district is divided into the three administrative talukas Madikeri, Virajpet (Viraranjendrapet) and Somwarpet. Madikeri, Somwarpet, Kushalnagar, Virajpet and Gonikoppal are major urban centers of Kodagu district.
The Coorg district comprises of people of distinct ethnic and caste origins like Kodava, AreBashe Gowda, Kodagu Mappila, Tulu, Devanga, Malayali, Tamil, and other communities. One fifth of the kodagu population consists of Kodavas and they are ethnically distinct from the other people of the area. The Kodavas/Coorgies are traditionally agriculturists and warriors.
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I reviewed a recipe book recently called Lola's A Cake Journey Around The World and as part of my review I made an Amarula Cake from the book. I really enjoyed it as it contained some of my favourite flavours – chocolate, caramel and whipped cream. I also have a new love for Amarula! It's similar to Baileys in that it's a cream liquor, but it's made with a fruit from South Africa called the marula fruit. I really wanted to make the cake again but I wanted to amp it up and really make it indulgent and special, so this Amarula, Chocolate & Caramel Cake was created!
I started by mixing 120g cocoa powder with 250ml boiling water, then left it to cool. I whisked up 6 eggs, 440g caster sugar and 120ml vegetable oil with an electric hand whisk until it was frothy. I added the cocoa powder mixture and whisked it in.
Then I added 500g self raising flour, 1 tsp baking powder and 2 tbsp Amarula and folded it in. I separated the mixture into three 22cm cake tins and baked on 180C/160C Fan/350F/Gas Mark 4 for 25 minutes.
I made a buttercream by mixing together 450g baking spread, 4 tbsp Amarula and 900g icing sugar. I stacked up the sponges, drizzling 1 tbsp Amarula on each sponge before spreading them with some buttercream.
I covered the sponge in a base coat of buttercream and put it in the fridge for 1 hour to set.
I took it out and covered it again with the rest of the buttercream and I smoothed it out as best I could.
To decorate the cake I carefully piped blobs of the caramel on the edge of the cake, then covered the whole top of the cake with a thin layer of the caramel. I whipped up 200ml double cream, 3 tbsp Amarula and 2 tbsp icing sugar and piped it around the edges. I added bronze sprinkles and white chocolate stars in the centre, then cut some chocolate squares I got from The Chocolate Trading Co into triangles and stuck them into the cream. Finally a spritz of gold glitter finished it off!
This cake was everything I had dreamed of! Rich chocolate sponge, sticky caramel drizzle and sweet buttercream with Amarula flavour. It would make a fabulous cake for a celebration, or the ultimate way to treat yourself!
I'm linking these cake up with some blogger link ups this month. Cook Blog Share hosted this month by Hijacked By Twins, and We Should Cocoa hosted by Tin & Thyme.
Pin this recipe for later!
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Amarula, Chocolate & Caramel Cake
- 120 g Cocoa powder
- 250 ml Boiling water
- 6 Eggs
- 440 g Caster sugar
- 120 ml Vegetable Oil
- 500 g Self raising flour
- 1 tsp Baking powder
- A pinch of Salt
- 12 tbsp Amarula
- About 1/3 can of Carnation Caramel
- 900 g + 2 tbsp Icing sugar
- 450 g Baking spread
- 200 ml Double cream
- Sprinkles of your choice
- 10 Chocolate Duo Panels
- Gold Edible Glitter
Mix the cocoa powder with the boiling water and leave to cool
In a large mixing bowl, use an electric or hand whisk to mix the eggs, caster sugar and vegetable oil until frothy. Then, add the cocoa powder mixture and whisk it in
Gently fold in the self raising flour, baking powder, salt and 2 tbsp of the Amarula
Separate the mixture into three greased and lined 22cm cake tins and bake on 180C/160C Fan/350F/Gas Mark 4 for 25 minutes (check they are done by inserting a skewer or thin knife into the centre, it should come out clean). Leave them on cooling racks to cool completely
To make the buttercream mix together 450g baking spread, 4 tbsp Amarula and 900g icing sugar until smooth
Stack up the sponges, drizzling 1 tbsp Amarula on each sponge before spreading them with some of the buttercream
Cover the cake in a base coat of buttercream and put it in the fridge for 1 hour to set
Cover the cake with the rest of the buttercream and smooth it out as best you can using a palette knife or scraper
Put the Carnation Caramel into a piping bag and carefully pipe blobs on the edge of the cake so it drips down. Then cover the whole top of the cake with a thin layer of the caramel
Whip up the double cream along with 3 tbsp of the Amarula and the 2 tbsp of icing sugar, pipe it around the edges of the cake
Add sprinkles in the centre of the cake, then cut the chocolate duo panels into triangles and stick them into the cream. Finally spritz with gold edible glitter


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TopicCortex e-Sports Looking For League of Legends team
Currently Looking for some highly skilled players to form a League of Legends team under the Cortex Organisation
This is your chance to play and represent a professional and well established organisation in a game that you not only love to play but believe have what it takes to get to the top.
Current Lineup: Unknown
Currently looking for:
* Highly Skilled Players- We are looking for players who generally understand the game and are a cut above the rest. Currently looking for all roles.
* IGL: Looking for a willing IGL who can be online and help train the team with strat prac also being able to call under pressure in game.
* Sub1/2: Looking for 2 SUBS who are online most days to go through some training with the team, and able to sub in anytime they are called in. Able to play everyrole.
Other things needed:
- Dedicated player, willing to Prac/scrim at late times Sunday-Thursday(9pm-12am) (flexible). (If player has other obligations).
- Must not be toxic or defensive person able to take and give constructive criticism without getting mad.
- In game decision making skill is a must.
- In game comms and call outs very important.
- Is friendly and mature.
-A player than can travel around OZ if necessary for LAN events.
-A player that plays other games and wants to hang out in discord when we are not grinding LoL
Contact Me:
Steam: http://steamcommunity.com/id/StingRayz_/
Twitter: https://twitter.com/StingRayz_
Cybergamer: https://au.cybergamer.com/profile/124293/StNGRAYZ/


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It's that time of year again, yes, it is bowl season. For the 3rd straight year, Oregon is in the BCS, and is in search of their first Rose Bowl win in 95 years.
This video will accomplish two things. It will introduce you to Wisconsin's strengths and shortcomings, and will also give you insight into Oregon's offense as they prepare for their matchup with the Badgers.
Wisconsin's defense is what everyone likes to call a typical Big 10 defense. They are big, strong defenders, built to stop a team with two tight ends and a full back, running dives and power plays on every down. To put it simply, Wisconsin is a perfect fit for their conference.
[tubepress video="R4ZrI8ph8dE" embeddedWidth='534′ embeddedHeight='314′ title="false" length="false"]
Next week, we'll take a look at the high powered Wisconsin offense and try to find a way to stop the Badgers.
I will be sending emails with links to recent articles in the near future so you don't miss any juicy ones. We will have articles between Monday and Thursday every week, so if you sign up for the "FishLetter" with your email–no spammer will have it. (Promise)
Or send it by email to: firstname.lastname@example.com and I'll put you on the list. We begin them soon.
(I will also put my thoughts in these emails/newsletters that cannot be publicly published throughout the football season as well. (Mr. FishDuck)


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Groundhog Day?? Don't be so sure!
by Bella Rum
I watched Valentine's Day last weekend. H walked in somewhere in the middle and asked what I was watching.
We don't do much to celebrate Valentine's Day, or any other holiday for that matter. We're not exactly celebratory kind of people. That's not entirely true. We celebrate the forty years we've been together, the joy, the deep love and devotion …. okay, we don't. We don't celebrate any of that.
We don't buy gifts, give cards, write poetry or give each other flowers. We might give each other a little punch in arm and say, "Hey, kid." But that's the fullest extent of holiday-acknowledgment we can bring our non-celebratory selves to participate in.
We do hug a lot all year-long. We're not inhuman. Just wanted to clear that up.
We're good with our non-celebratory ways. Really. There are no unrealistic expectations after forty years. When he missed birthdays or anniversaries early in our marriage, I did the hurt feelings thing a few times. Then I let him off the hook. He's a good guy all the other days.
We kind of do the lovey thing a little each day. We're pretty nurturing to each other, just not particularly on holidays. If he cuts his finger nearly clean off, I take him to the emergency room, if I need a cardioversion, he updates my blog for me. We don't save it up for the big day. Know what I mean?
But after watching Valentine's Day, I had the urge to do something… well… celebratory.
Bella ~ We could do something special for Valentine's Day this year.
H ~ Yeah. We could. (not too convincing)
Bella ~ Something different.
H ~ Yeah. We could. (uncharacteristically suspicious)
Bella ~ Break the mold, be bold and celebrate.
H ~ What'd you have in mind?
Bella ~ I don't know. We could eat beef.
H ~ Beef?
Bella ~ Yeah, beef. We could buy a couple of fillets and bake a couple of potatoes and put butter and sour cream on them and make a big old salad with blue cheese dressing and a loaf of french bread with garlic and butter and have cheese cake for dessert – a real heart-stopping, 1970's kind of meal… like we used to do back in the day when we still had clean arteries.
H ~ Okay. Valentine's day is on a Wednesday, but hopefully I'll get home early. We'll do it.
Bella ~ Wednesday? That's kind of sweet, H. You've looked at a calendar and actually know what day Valentine's day falls on?
H ~ Well, today is Sunday and it's the 30th. It isn't that big of a stretch to figure out that Wednesday is the 2nd.
Bella ~ …..
H ~ What?
Bella ~ …..
Bella ~ The 2nd of February is not Valentine's Day! It's Groundhog Day!
H ~ No.
Bella ~ …..
H~ No.
Bella ~ …..
H ~ You're going to tell everyone on that blog, aren't you?
Happy Valentine's Day from H!


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- You are here:
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- Wellbeing
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If you're not quite sure you want to swallow a spoonful of honey every night before bed, how about stirring it into a hot drink instead?
Your comments
- Healthy cereal: The best and worst cereals revealed
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- Best bob hairstyles


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- select colour
it's an internet thing!
it's an internet thing!
"It was great fun. We had gone on tour in between the sessions and reconnected with the audience and got a lot of energy back from them, a lot of positive energy."
"The gift of fantasy has meant more to me than my talent for absorbing positive knowledge."Roger Andrew Taylor on Albert Einstein
"I do believe we're all connected. I do believe in positive energy. I do believe in the power of prayer. I do believe in putting good out into the world. And I believe in taking care of each other."Roger Andrew Taylor on Harvey Fierstein
"Once you replace negative thoughts with positive ones, you'll start having positive results."Roger Andrew Taylor on Willie Nelson
"Positive thinking will let you do everything better than negative thinking will."Roger Andrew Taylor on Zig Ziglar
"If you're not making mistakes, then you're not doing anything. I'm positive that a doer makes mistakes."Roger Andrew Taylor on John Wooden
"It's amazing to see places like Madison Square Garden on the schedule again."
"Nick and Simon had come to a natural end of their working relationship with Warren, which obviously opened the door for a reunion of the original five."


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Junior Consultant - Lean Services
- Undergraduate or master's degree or have 1 - 3 years of work experience after completing your undergraduate degree
- Strong knowledge of lean operations, e.g., Kaizen, Six Sigma tools
- Experience in planning and executing business performance transformations (e.g., comprehensive process optimization, lean management) using Six Sigma and other lean concepts in service industries
- Demonstrated aptitude for analytics
- Proven record of leadership in a work setting and/or through extracurricular activities
- Ability to work collaboratively in a team environment
- Ability to work effectively with people at all levels in an organization
- Skills to communicate complex ideas effectively in English
Who You'll Work With
You'll be working with McKinsey's Operations practice in the UK. Our Operations practice assists our clients in solving complex operational challenges. Blending strategic thinking with hands-on practicality, our teams of consultants and experts work to develop and implement operational strategies that solve our clients' most critical problems.
What You'll Do
You will typically work in teams of 3 – 5 consultants to help clients achieve new performance highs.
You will make an important contribution to the analysis, design, and implementation of Lean Manufacturing approaches, developing tailor-made solutions and working closely with clients to ensure positive impact and sustainable results. This includes gathering and analyzing information, formulating and testing hypotheses, and developing recommendations for presentation to client management. From there, you will implement those recommendations with client team members.
You'll also gain new skills and build on the strengths you bring to the firm. Consultants receive exceptional training as well as frequent coaching and mentoring from colleagues on their teams. In addition to working directly with clients, you will also share your experience and insights with colleagues internationally, thereby expanding our knowledge and refining our approaches in the field of Lean Manufacturing.
Meet Some of McKinsey's Employees
Danielle B.
Danielle is one of the leaders of McKinsey's business with retail and consumer clients. She oversees client projects and helps her teams and her clients utilize McKinsey's resources.
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Best Exercises To Train With Before Your Next Snowboarding Trip – Shaping Up To Hit The Snow
Despite the fact that we get the opportunity to snowboard on a regular basis during the season we still feel like it is an exceptionally extraordinary treat to get the chance to go snowboarding so often. Its an opportunity to invest our energy outside, to work out, to test the limits of ourselves, to associate with companions all while unwinding and having a fabulous time. Snowboarding allows all of us to get our heart rates up while finding joy and beauty in the unstoppable forces of life which are both perfect ways to reinforce well being. Regardless if its getting a new powder day in, hitting snowboard parks for a few tricks, going on some back country runs or simply unwinding on the bunny slopes with the little children snowboarding really provides something for everybody to enjoy and participate in. Snowboarding permits you to express yourself while also giving you the capacity to turn on your innovative side. While most of us comprehend why snowboarding is so much fun we think there are certain approaches we can take to add considerably more happiness to your experience on the mountain and we believe exercise and staying fit is a big factor in the this. Working out can play a major role in how ready you are for the snowboarding experience which is why we always encourage more of it for all levels of Snowboarders. Here are a few of the more sport specific exercises you can do to really prepare your body for the times you will be out on the Mountain shredding.
Snowboarding Exercise Tip and Trick Number 1: Squat Leaps
For this exercise you will want to begin with your feet shoulder-width apart. Squat down so your thighs are parallel to the floor, then leap as high as you can into the air while attempting to land gently on the balls of your feet. You can perform this workout almost anywhere and requires no equipment which is why we love it. This will help you develop your quads and gluteus which is ideal for the carving and aggressiveness of snowboarding.
Snowboarding Exercise Tip and Trick Number 2: Standing Single Leg Bends
Another exercise that requires no equipment and little room is the standing single leg bend which is one of our favorites as well. Performed by lifting your left leg behind you and slowly bend your right knee (right knee should not pass the front right toe), and then coming back up and repeating. When you get to your last repetition try holding it and counting to 30 seconds, Switch legs and reps as appropriate. Again we are working on our legs, balance and coordination all of which can do wonders for our snowboarding prowess.
Snowboarding Exercise Tip and Trick Number 3: The Plank
All the plank really comes down to is getting into the starting position for a pushup. With your hands underneath your shoulders hold your core and butt tight for twenty and thirty seconds at a time and then repeat as needed. One thing we really about the plank is not only are there a lot of different variations to try but also that it gives us that full body workout we love to have as snowboarding often test all your muscles. If you are looking for entire snowboarding preparation exercise or workout routine its worthwhile to start reading reviews like the CIZE reviews to find the perfect program for your specific situation and needs.


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Published on Jan 29, 2013
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pictures are legal property Michelle A.
On as .
interviews asian girl toying Jamisontown black and
Bullied hard to miss.
Body, Bed! Lane In Charlee Cove MILF Dc Chase you have
And security, and reliability of the 2nd october i saw one of the above described symptoms and I will bat at you for what I want to a judge. The Harrises missed several opportunities for self-development throughout their academic performance.


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I had the distinct honor of having Gary Reinl stop by my gym, the Cave, while he was in town working with a Pro sports team and take the time to do this podcast.
His approach to recovering from injuries makes too much sense to ignore.
I had the distinct honor of having Gary Reinl stop by my gym, the Cave, while he was in town working with a Pro sports team and take the time to do this podcast.
His approach to recovering from injuries makes too much sense to ignore.
Anyone who lifts heavy and hard knows how important it is to get adequate rest and recovery. In fact, all those who train hard, even if they are in a non-barbell sport, know this.
However, many people sabotage their recovery through excessive amounts of stress. Much of that stress comes from being completely immersed in social media. I mean they cannot live without checking Facebook a gazillion times a day.
Another source of high stress is the news, real or fake doesn't matter. It keeps people in a constantly agitated state of mind.
People rant and rage about all manner of things they cannot do one thing to change.
For instance, people are ticked off about the election. Big deal, I have been ticked off about numerous elections over the decades, and it didn't make one bit of difference in any of them.
So, if you want to recover more effectively, here's some things that should help
I am studying this book now and it is one of the most informative I have read in quite a while, and I read a lot of books.
Scott Iardella shows numerous reasons why strength is so important all through life, but especially as you age. He covers some subjects in depth that many people may not have looked into before, like muscle wasting (sarcopenia).
The Edge of Strength: An Unconventional Guide To Live Your Strength And Discover Your Greatness
In support of Movember (mens health awareness month) I just wrote an article on my other blog about being active and fit all your life.
Too many guys are dying way too you! It shouldn't be that way and doesn't have to be!
One thing I hate is someone trying to make me think, act, and live how they think I should at a certain age.
They first try to get to you when you turn 50 and they send you an invitation to join a very large "geezer's" organization (it starts with the letter "A").
Forget it! Quit calling me a Senior Citizen, I keep that I am only approaching middle-age in my mind! I refuse to think old!
I feel 1/2 my chronological age.
Each year they throw more stuff at you that they automatically "just know" you have to have (this is in addition to all the prescription medications for high blood pressure, high cholesterol, depression and sexual dysfunction that they have conned many people into using)
They can flush all that junk!
All of it is for their profit, not your health and well-being.
I ain't going for any of it!
Folks, don't buy their lies!
Think for yourself and take action every day.
Surround yourself with strong, smart, trustworthy people and you will prove all the slick marketers wrong! You DON'T need their junk!
Unless you are living under a rock, you see and hear this poison every day.
On the Internet, hate is at epidemic proportions.
In traffic, people are ready to kill others because they don't like how they drive.
People are seething with rage, bitterness, and vengeful thoughts.
Even if they don't act out those thoughts, they are still wrecking their own health and lives.
Here's the thing, you don't have to get sucked into this mess.
Here's a few ways to avoid this trap:
Your thoughts eventually become your actions, good or bad.
The ancient writings remind us "let every man be swift to hear, slow to speak, slow to anger" Book of James 1:19
Summer is just about here and so is the next "fat panic" across America.
This occurs around New Years also. It is very predictable.
The unreasonable fear of looking bad in a bathing suit suddenly hits those who have neglected their health and fitness all the rest of the year.
Here's the main problem, though:
You can help prevent your family and friends from getting suckered by the con artists out there by making them aware of this. Some still won't listen, but some might.
The people who will look great in a bathing suit his summer are already in excellent shape, they bare not in panic mode. They trained all winter. There are NO shortcuts or magic formulas!
My approach overall is strength and fitness are the main priorities
However, train the right way for strength and fitness and the improved looks are just a byproduct of that.
Don't let the people you care about get suckered!


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Information about .13 File Extension
Common .13 file type descriptions:
- 13 File
- Файл "13"
- Creo Versioned File
- Plik 13
- 13-Datei
Applications, associated with .13 files
|Notepad by Microsoft Corporation
Notepad is a simple text editor for Microsoft Windows. It has been included in all versions of Microsoft Windows.
|Thunderbird by Mozilla Corporation
|Paint by Microsoft Corporation


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Our Mission
It's Back to School Time!
Our PCEF volunteers are gearing up for our Pack-a-Backpack Program, which provides grade-appropriate school supplies and backpacks to students in need in the Phoenixville area. If you would like help, you can shop our Amazon Wish List, drop off school supplies at a participating business, make a cash donation, and/or contact us to volunteer. Click here to learn more…
There are many ways to get involved with PCEF. We are always looking for volunteers to help with various projects and causes. Click here to learn more…
Thank you for your interest in making a donation to the Phoenixville Community Education Foundation. Your gift will support our mission to enhance and support educational opportunities in Phoenixville. Click here to donate to PCEF.
Our Programs
PCEF endeavors to provide funding for programs and projects not funded by the school district budget, including after-school clubs and organizations, area pre-schools and community organizations delivering outside the school day educational enrichment programs.
Thank You to our 2017 Corporate and Community Partners
Latest News
Pack a Backpack Update and Save the Date
Once again, you and our community ensured that all students had backpacks and school supplies for the first day of […]
School Supply Drive 2017
It's Back to School Time!
Wait, didn't summer just start?! Many people don't start thinking of back-to-school until August, but our […]
PCEF Scholarships Awarded
PCEF was pleased to award scholarships to several graduating seniors! Sarah Dathe and Hong Dinh received PCEF scholarships, Alaina DeLeone […]
Save the Date! We have a lot to celebrate
This fall marks 15 years since Phoenixville Community Education Foundation was founded! To celebrate this milestone, we are planning a […]
Thank you EITC Donors
Thanks to the efforts of state representatives Becky Corbin (R-155) and Warren Kampf (R-157), PCEF received a $10,000 EITC grant […]
Phantom Fundraiser Tickets on Sale!
Purchase your Phantom Fundraiser tickets today! Click here for our newsletter.


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Do-It-Yourself streets & neighborhood makeover in London
Posted June 1, 2011 at 1:30PM
DIY Streets is a sort of grassroots-oriented neighborhood improvement program in the UK, sponsored by the British organization Sustrans. It strikes me as somewhat like the Texas-based "Better Block" initiatives in the US, but more permanent, combined with a complete streets philosophy and partially designed by activist parents pursuing traffic calming for neighborhood safety.
Laura Laker writes on the Green Living Blog of The Guardian:
"Clapton Terrace is one of 11 'DIY Streets', a nationwide project launched by sustainable transport charity Sustrans as a cheap solution to local traffic problems. By narrowing and raising sections of road to pavement level, planting trees and using street furniture and bollards, the scheme forces drivers to slow down by blurring the distinction between space dedicated to cars and pedestrians.
"Two years ago locals were fed up as drivers were using their street as a shortcut to avoid a busy junction nearby. They resurrected their residents' group and got together to vote on their own DIY Street . . . The road now feels a lot more spacious as two trees were added beside the road, communal wheelie bins replaced 64 individual bins, and a fence around the nearby green was removed. The site also uses Plantlocks – boxes of plants with bike-friendly bars – where residents can lock bikes."
The next step is apparently a pilot project to take the concept beyond a single street to the neighborhood scale.
Streetfilms has produced a nice short video profiling the Clapton Terrace project. Enjoy:
Move your cursor over the images for credit information.


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Western Connecticut State University admission application fee
Think about what career is best suited for you, and where you want to study. Request more information now.
Think about what career is best suited for you, and where you want to study. Request more information now.
Think about what career is best suited for you, and where you want to study. Request more information now.
Get the facts about Western Connecticut State University admission application fee, and registering for elective lectures and seminars. Which college degrees give you the best chances of entering a successful career path after graduation? Concentrating on Western Connecticut State University admission application fee, for example, may give you additional focus in the admissions selection process. Check with the admissions office for assistance with prerequisites, course registration deadlines, and college degree program requirements. Please use the form above to request admissions info for Western Connecticut State University.
As the admission's office must sift through many college application forms, your goal is to stand out in a good way. If you already have top grades and high SAT or ACT scores, you can still improve your application, given other factors such as talent in sports, the quality of your essay topic, and extracurricular activities. The admissions essay is gaining weight at selective colleges, but please be aware that on average, a typical college application only receives 25 minutes of reading time. Therefore, keep your application brief, and stick to the point when answering questions.
Admissions officers seek to learn how a given applicant thinks, what kind of person they are, and their level of intellectual promise. Many colleges are paying greater attention to a student's grades not only in core courses, but in AP classes and in honors courses as well. In fact, an ideal academic record is one of progressively better grades, in classes of increasing difficulty. It is optimal to try taking the hardest courses that are offered, and that the worst thing you can do in terms of getting into college is to drop a hard course just because you fear getting a low grade. Beyond major requirements within the admissions department, you may consider Fashion Institute of Technology graduating class for complementary electives to your primary course of study.
Academic Advisor
Ivy Tech
Utilize a communication plan to engage the college community in the academic advising process. Maintain academic advising records.
7 days ago Educational Center Director
FLEX College Prep
FLEX COLLEGE PREP. Since that time, FLEX has expanded to include a multitude of other services, including academic and college admissions counseling.
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Miller-Motte College
The Admissions Representative also represents Delta Education accurately and compliantly at student recruitment events.
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Lorien Mays Chapel
College degree preferred. Conducts admission screening of potential patients, determine level of care, services required, equipment needs, insurance coverage.
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Year Up
Reporting to the Admissions Manager, the Admissions Specialist - San Francisco, CA will serve as a key contributor to screen applicants and enroll students each..
7 days ago


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In this post we have analysed the Zygor Elite guides (which includes leveling, profession, achievments and so on) with a critical and impartial view.
I've always liked to play WOW, but with World of Warcraft: Legion being released my motivation to revisit the old leveling ground has somewhat lowered. This is the same with every expansion, more grinding to reach the top level. With the level cap increased to 110 a long process of leveling becomes even longer if you want to get an alt of another class to the top level. That's why I considered getting a World of Warcraft: Legion leveling guide.
If you're like me and enjoy the endgame at the top level like battlegrounds, arena and raiding way more than the path to get there the desire to start all over again with a new character decreases. Sure, Blizzard updated the old zoned in Cataclysm but for me it still didn't do the trick.
For these reasons a Legion leveling guide as the one by Zygor is invaluable. Simply because of the time and frustration you don't have to suffer through. Even if you're like me and have most of the quest lines memorized the Zygor leveling guide still help speed up the process. That's because of features like waypoints for everything necessary, automatic quest accepting and turn in.
Obviously the World of Warcraft: Legion leveling guide offered by Zygor will also be of use to the new players that want to reach the maximum level as quick and hassle free as possible. It doesn't matter if you just want to get to play the endgame as fast as possible or want to experience the way there in a more relaxed way. Zygor's leveling guide gives you the ability to spend more time enjoying the game and the new expansion instead of trying to figure out what you're going to do 80% of the time.
I've added a quick list of the World of Warcraft: Legion leveling guide has to offer.
- Probably the best feature. The direction system by a waypoint that shows you where you are going and helps identify targets, locations or NPCs.
- Instruction of everything you can think about. Everything is step by step on what to do and what items to prepare to avoid backtracking. And this is not just limited to leveling.
- Zygor's World of Warcraft leveling guide will integrate itself with your questing and leveling progress. This is my favorite feature. You can start using it on whatever character you like whenever you like. It will detect where you are in the game and what is needed to do to proceed. It also gives you the option to break the chain of quests and level with dungeons or battleground when you feel like doing that.
Some other features for the in-game guide are automated flight paths, automatic quest accepting along with several other settings you can adjust to suit your needs.
Summary: The World of Warcraft: Legion leveling guide by Zygor has the complete set of tools you need to make the gaming experience as smooth and enjoyable as possible. Getting rid of all the doubts and making it easy to see your objectives is only one of the things the in-game guide has to offer. It certainly is the best Legion guide out there.


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Welcome to the White Shirt live comment thread for Handel's "Agrippina" (2000) from the La Monnaie Brussels, staged by David McVicar and conducted by René Jacobs.
Cast Listing:
Anna Caterina Antonacci – Agrippina
Rosemary Joshua – Poppea
Lawrence Zazzo – Ottone
Malena Ernman – Nerone
Lorenzo Regazzo – Claudio
Dominique Visse – Narciso
Antonio Abete – Pallante
The production is available on YT thanks to jovi1715 and can be accessed via thadieu's handy playlist.
Libretto: German, English and Italian (html), Italian (pdf)


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Hanoi (VNA) – A Singaporean senior official said on September 4 that the country's Ministry of Health (MOH) is reviewing the regulation of isolating patients with high risk of Zika infection.
Amy Khor Lean Suan, Senior Minister of State at the Ministry of the Environment and Water Resources, was quoted by Straits Times as saying that the MOH is considering the ability of allowing patients suspected of Zika infection to get treatment at home during the tests of blood and urine.
The ministry has also considered the possibility of allowing Zika-infected patients to return home for rehabilitation but warned them of avoiding being bitten by mosquitoes.
At present, those who are thought to be infected with Zika virus are being isolated at the Communicable Diseases Centre while waiting for test results. Meanwhile, people who are positive to Zika virus are being isolated at hospitals.
On September 3, Singaporean authorities reported 26 new cases of Zika infection, bringing the total number to 215 since the first one was found on August 27.
Zika virus is spread from human to human mainly via bites from Aedes aegypti mosquito and infected people often have symptoms such as f ever, rash, conjunctivitis (red eyes), muscle pain and headache.
No vaccine has been created to prevent or treat Zika virus infection.-VNA


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From "Compassion and the Mission of God: Revealing the Hidden Kingdom" by Rupen Das .
Most people find meaning in life as they discover their place within a narrative that they feel explains the world and life for them. In the pluralistic world we live in, there are competing narratives about the meaning of life and about our relationship and obligations to society. Most of these narratives are usually not communicated through a comprehensive philosophical presentation, but through the exploits of heroes and role models, through parables, stories and folk wisdom, through advertisements, commercials and TV sitcoms, and occasionally through religious education. They are the tools and vehicles through which ideas and values are communicated. Philosopher Nassim Nicholas Taleb author of The Black Swan: The Impact of the Highly Improbably writes, "Metaphors and stories are far more potent (alas) than ideas; they are easier to remember and more fun to read…Ideas come and go, stories stay."[1]
While narratives have their limitations because they tend to simplify reality rather than explain its complexity, narratives are important and powerful because they are able to embody ideas within real contexts and thereby giving meaning to events in history and in life. Canadian sociologist at the University of Calgary, Arthur Frank, writes about how stories influence and shape human behavior.
Stories animate human life; that is their work. Stories work with people, for people, and always stories work on people, affecting what people are able to see as real, as possible, and as worth doing or best avoided…. Human life depends on the stories we tell: the sense of self that those stories impart, the relationships constructed around shared stories, and the sense of purpose that stories both purpose and foreclose.[2]
Unfortunately narratives are viewed as an inferior form of communicating truth in our technological age. Professor of homiletics, Paul Borden writes, "Our literate technological culture has convinced us that truth cannot be communicated [through stories]. Stories may be used to illustrate truth but not communicate it…While analytical and logical presentations are sometimes required and beneficial, the assumption behind such presentations is often one of disdain for narrative as the means for communicating major ideas…However, more people in culture are influenced, not by papers and books by philosophers, ethicists or commentators, but by the artistic communication of their ideas in the media…In other words, it is the stories and ideas taught by stories that influence people…"[3] Is it any surprise that a major form of communication in the Bible are narratives and stories.[4]
When it comes to the narrative of the Bible as a whole, there are different understandings of what the larger narrative of the Bible is. Some focus on the issue of justice and the theme of God liberating people from social and economic bondage. Others focus on a God who blesses, heals and prospers. Yet others focus on the eternal dimensions, specifically life after death. Many focus on the love of God, and God wanting to fulfill us and make us everything that we were intended to be, in the process freeing us from our psychological bondages. The Biblical narrative is often understood as having four parts – creation, fall, redemption and new creation. Craig G. Bartholomew and Michael W. Goheen offer the Biblical narrative as a six-act drama: creation, fall, redemption started with Israel, redemption accomplished in Christ, the church, and the final consummation.[5]
Is there a larger narrative about a Creator God redeeming not just human beings but all of creation; where history and time have a purpose "to bring unity to all things in heaven and on earth under Christ" (Eph. 1:10) and that there will come a time when it will be said, "The kingdom of the world has become the kingdom of our Lord and of his Messiah, and he will reign for ever and ever." (Rev. 11:15) Is not the Biblical narrative about the eternal King who is the Creator, and about His Kingdom? The issues of justice and liberation, redemption, blessings, the love of God, hope, eternal life and wholeness in this life, are all realities of the Kingdom of God and not separate narratives. It is critical to understand this, because the narrative provides the context for the truth to be understood and then communicated. American theologian Alan E. Lewis wrote, "narrative is now being tested as theology's starting point, in response to which, and in reflection upon which, concepts, doctrine, and prescriptions for action may subsequently be constructed."[6]
In the midst of the discussion of the Biblical narrative, it is important to remember who the Narrator is, even as He speaks through the limitations and individuality of the human writers. The Biblical narrative is not only unique in that it addresses the issues of evil and injustice, but is all the more astounding as it gives meaning to an absolutely magnificent, incredibly beautiful and terrifying universe. It is the story of a Creator, of love spurned, redemption and second chances. It describes justice and judgment, and the intriguing possibility of forgiveness. It is a story of an eternal Kingdom and its King. This narrative is not a fairy tale or a Russian novel grappling with the existential questions about life and society. Instead, it is the history of time. Brian Wicker writes, "The claim to be able to tell such a story amounts to the claim to be in the position of God."[7]
The Annales School is a style of historiography developed by 20th century French historian Fernand Braudel and others that studies long-term social history referred to as la longe duree. Rather than focusing on "episodic events or the public deeds of Great Men",[8] they pioneered an approach that looked at the influence of geography, material culture and the psychology of the period on history. William Dever, professor of Near Eastern archeology at the University of Arizona writes, "They looked rather at history as the result of cultural adaptation to the "deeper swells" of changing natural conditions over the millennia."[9] Too often the study of Scripture has focused on narrow and specific issues, or on individuals and heroes without understanding the larger narrative of God's work, as well as the history and the context of the Bible. This book will revisit some of the biblical narratives to try and understand where the poor and the broken fit within the economy of God and why. Understanding this will provide the basis for a theology of compassion.
[1] Nassim Nicholas Taleb, The Black Swan: The impact of the highly improbable, (New York: Random House Trade Paperbacks, 2010), xxxi.
[2] Arthur W. Frank, Letting Stories Breathe: A Socio-Narratology (Chicago, IL: The University of Chicago Press, 2010), 3.
[3] Paul Borden, Is There Really One Big Idea in That Story? In "The Big Idea of Biblical Preaching", ed. Keith Willhite and Scott M. Gibson (Grand Rapid: Baker Books, 1998), 68.
[4] For example, Klyne Snodgrass estimates that more than one-third of the teaching material recorded in the synoptic Gospels are parables. Klyne Snodgrass, Stories With Intent: A comprehensive guide to the parables of Jesus (Grand Rapids, MI: Eerdmans, 2009), 22. (Snodgrass 2009)
[5] Craig G. Bartholomew and Michael W. Goheen, The Drama of Scripture: Finding Our Place in the Biblical Story (Grand Rapids, MI: Baker Academics, 2004), passim.
[6] Alan E. Lewis, Between Cross and Resurrection: A Theology of Holy Saturday (Grand Rapids, MI: William B. Eerdmans Publishing Company, 2001). 10. Lewis writes about the impact of narrative theology. "On the surface at least, this is, therefore, an inauspicious, even perilous, moment for theologians of many varieties and all confessions to agree that it is precisely the genre of the story, or narrative, upon which they should concentrate their analysis of how truth is conveyed, and with which they should begin their attempts at communication… "Stories" have recently emerged in much theology as the very means by which the truth of God is understandably received and effectively passed on by the community of faith." Ibid, 10.
[7] Brian Wicker, The Story-shaped World: Fiction and Metaphysics: Some Variations on a Theme (Notre Dame: University Press, 1975), 101.
[8] William A. Dever, Who Were The Early Israelites And Where Did They Come From? (Grand Rapids, MI: William B. Eerdmans Publishing Company, 2003), 133.
[9] Ibid, 113.


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Conceived and designed the experiments: SHJK WY CAH. Performed the experiments: SHJK WY. Analyzed the data: SHJK. Contributed reagents/materials/analysis tools: KEM MAM. Wrote the paper: SHJK CAH.
The authors have declared that no competing interests exist.
Primary human alveolar type II (AT II) epithelial cells maintained in Matrigel cultures form alveolar-like cysts (ALCs) using a cytogenesis mechanism that is different from that of other studied epithelial cell types: neither proliferation nor death is involved. During ALC formation, AT II cells engage simultaneously in fundamentally different, but not fully characterized activities. Mechanisms enabling these activities and the roles they play during different process stages are virtually unknown. Identifying, characterizing, and understanding the activities and mechanisms are essential to achieving deeper insight into this fundamental feature of morphogenesis. That deeper insight is needed to answer important questions. When and how does an AT cell choose to switch from one activity to another? Why does it choose one action rather than another? We report obtaining plausible answers using a rigorous, multi-attribute modeling and simulation approach that leveraged earlier efforts by using new, agent and object-oriented capabilities. We discovered a set of cell-level operating principles that enabled in silico cells to self-organize and generate systemic cystogenesis phenomena that are quantitatively indistinguishable from those observed in vitro. Success required that the cell components be quasi-autonomous. As simulation time advances, each in silico cell autonomously updates its environment information to reclassify its condition. It then uses the axiomatic operating principles to execute just one action for each possible condition. The quasi-autonomous actions of individual in silico cells were sufficient for developing stable cyst-like structures. The results strengthen in silico to in vitro mappings at three levels: mechanisms, behaviors, and operating principles, thereby achieving a degree of validation and enabling answering the questions posed. We suggest that the in silico operating principles presented may have a biological counterpart and that a semiquantitative mapping exists between in silico causal events and in vitro causal events.
Many internal organs in metazoa comprise liquid or gas filled cystic structures surrounded by a layer of epithelial cells. How such hollow structures are formed is a central problem in morphogenesis and tissue regeneration. Hollow structures are formed in vitro by a wide array of mechanisms
However, the task is complicated by the fact that during cystogenesis, different cells can be simultaneously engaged in fundamentally different activities. For example, one AT II cell can be moving about within a cell cluster while another is migrating alone, and another is trying to attach itself to an early stage ALC, etc. No methods are currently available to comprehensively characterize either the variety of activities or their relative frequencies. Yet, the information is needed to answer such questions as these. When and how does an AT cell choose to switch from one activity to another? Why does it choose one action rather than another? Are several action options always available to each cell? Obtaining answers from in vitro studies is problematic because plausible answers are required in order to frame the hypotheses around which wet-lab experiments can be designed. Here, we report obtaining plausible answers using a rigorous, multi-attribute modeling and simulation approach that leveraged earlier efforts
The solution presented is based on the theory that when two
To distinguish simulation components and characteristics from in vitro counterparts, we use small caps when referring to the former. All systemic in vitro attributes are consequences of AT II cells interacting with each other and components of their environment. To create the analogue's mechanisms, we focused on the cell level, because cells are the system's primary functional units. We specified quasi-autonomous
We discovered a set of cell-level operating principles that enabled independent, interacting software objects, including those that mapped to individual AT II cells in vitro, to self-organize and generate systemic cystogenesis phenomena that were quantitatively indistinguishable from those reported in
We used the synthetic or constructive approach
We first identified and rank-ordered a list of attributes characteristic of AT II cultures. The result is provided in
|Order targeted
|Systemic attributes (primary human AT II cells; 3D Matrigel)
|Single cells, acting autonomously, migrate and cohere upon contact
|Cell clusters grow by aggregation only
|Cells do not undergo proliferation or apoptosis
|Cells in a cluster move collectively as a single structure
|Cell clusters fuse to form larger bodies
|Clustered cells shift their relative positions within the structure
|Cell clusters develop into ALCs, each with a central lumen enclosed by a monolayer of composing cells
|Larger ALCs form when the initial cell density increases
|Cell aggregation is inhibited but cell speed maintained when β-integrin function (cell adhesion) is blocked
|Cells moving slower in dense Matrigel form smaller clusters and thus smaller ALC
|Apparent density-dependent upper limit to ALC size; ALC size range limited
|ALC lumen is filled with secreted fluid, lamellar bodies, and surfactant
|Dose dependent increase in ALC size following treatment with forskolin
|Increased fluid transport results in larger ALCs with distended lumens and cells stretched
|The ALCs are polarized with apical plasma membrane facing the lumen
The list of basic AT II cell attributes in
We conceptually discretized AT II cell cultures into four components: cells, media containing Matrigel (matrix hereafter), matrix-free fluid (free or luminal space hereafter), and the space that contained them. We used objects to represent these components. To clearly distinguish simulation components and characteristics from in vitro counterparts, we use small caps when referring to the former. M
The model is a self-contained experimental system that comprises the core analogue and support components for experimentation and analysis (
The computational system consists of the core culture analogue,
Discrete objects with eponymous names represent the essential cell culture components:
Simulation time advances in steps corresponding to simulation cycles. Each simulation cycle maps to an identical interval of wet-lab time. During a simulation cycle, every
|Base value
|Number of Monte Carlo runs per experiment
|Simulation cycles executed per run
|Push iteration limit
|Pull iteration limit
|Grid unit distance moved per time step
|Grid unit distance moved per time step
0, random migration; 1,
We used observations reported in the literature to help avoid axioms that may have been judged abiotic and to prefer axioms for which supporting evidence was available. Absent evidence, variations of an axiom were implemented and the consequences (in silico predictions) observed upon execution. We then searched the time-lapse movies of experiments
Our plan was to discover and invent
Mappings from measurements taken on epithelial cell cultures to corresponding measurements taken in vivo are rarely 1∶1. They are often nonlinear and feature dependant. To establish a quantitative mapping, a mapping model is needed, necessitating specifying several assumptions. To enable a similar relationship between analogues and AT II cell cultures, we separated the mapping from analogue to referent from the actual analogue itself, and made the analogue fully relational. An advantage of doing so is that, as new wet-lab data becomes available, adjustments can be made to the mapping model without having to reengineer the analogue. Based on measurements of AT II cell migration, we devised a provisional mapping of analogue measurement units to in vitro metric units to enable direct comparison of simulation and in vitro data. Cells in culture swell, shrink, become more compact, and stretch as they form multicellular structures. Nevertheless, to specify the mapping, we assumed that average AT II cell shapes and sizes were relatively constant. In the current analogue, one grid unit corresponds to one
To the extent possible, design of simulation experiments followed the experimental design and protocols detailed in
We conducted standard
We investigated behavioral and phenotypic consequences of altering
The model framework was implemented using MASON Version 11. MASON (
The targeted AT II cell attributes are listed in
An analogue design objective was that simulation results exhibit specific characteristics that, when measured, would be quantitatively similar to corresponding measures of AT cultures. AT II analogues were abstract, working models of interacting, quasi-autonomous components. They were
Following the logic diagrammed in
(A–C) Phase-contrast pictures after 4 d in 2% Matrigel. (A) Cells were plated at 1×104 cells/cm2; (B) plated at 5×104 cells/cm2; (C) plated at 25×104 cells/cm2. ALCs were roundish without obvious depressions or dimples. Final ALC sizes were dependent on initial cell density. Bar: ∼50 µm. (D–F) Shown are images of simulated culture, after 100 simulation cycles (∼6.1 days in vitro), starting with AT II analogues parameterized as in
(A) Mean ALC diameters for both systems are graphed as a function of initial cell density. Open circles: mean in vitro diameter after 5.7 days; vertical bars: ±1 S.D. for 25 observations. Filled circles: mean analogue diameters after 100 simulation cycles (∼6.1 days) using the AT II analogues that achieved the most stringent Similarity Measure (SM-6); bars: ±1 S.D. for 100 simulations. The dominant migration mode used by all AT II analogues was
ALC frequencies within 5 µm intervals were measured after 5.7 days in vitro. The experiments are the same as those in
Analogue ALC frequencies within 5 µm intervals were measured after 100 simulation cycles (maps to ∼6.1 days in vitro) for each of the three migration modes. The frequencies were normalized to fraction of total count for each migration mode and then averaged over 100 analogue
In vitro, the average ALC size increased monotonically with initial cell density. We observed the same during simulations: mean values and their standard deviations are graphed in
Random migration of both AT II cells and clusters thereof is the simplest movement mechanism to simulate. However, inspection of the time-lapse in vitro movies (
Interestingly, when attention was shifted to cluster count, regardless of size or ALC status, we observed that
The frequency distribution of in vitro ALC diameters was dependent on initial cell density (
Individual axiom usage during the simulation experiments graphed in
Frequency of axiom usage is plotted versus simulation cycle for the AT II analogue as in
Usage patterns changed dynamically over time reflective of the changes in a
Cell-cell adhesion is a basic requirement for development of multicellular structures. In
To explore further the consequences of changing the
We expected that the kinetics of AT II cell-cell adhesion in vitro may vary between single isolated cells and cells that already had existing intercellular junctions. Analogues used two parameters to control the probability of attachment: one used by single
For simplicity, experiments were conducted using the random migration mode, as in
Alteration of
The observed results were somewhat unexpected but could be explained by analyzing analogue execution. For sparse
AT II cell and cluster migration speed was an important determinant of aggregation and ALC formation in 3D cultures. Intuitively, one would expect to form larger ALCs by elevating cell and cluster migration speeds. Doing so would increase the cell collision rate and thus accelerate aggregation. Conducting such experiments in vitro is infeasible because a minimum level of Matrigel is required to sustain normal AT II cell behaviors. Testing that hypothesis for AT II analogues was straightforward. We varied
All analogues used the
Using different
Analyzing analogue execution revealed that in dense
Identical simulation experiments using analogues that relied on the
Epithelial morphogenesis is tightly orchestrated in time and space. Understanding its complexities remains a challenge. Study of relatively simplistic, yet increasingly realistic, in vitro cell culture systems continues to provide mechanistic insight at multiple levels. Primary human AT II cells cultured in 3D Matrigel is a recently developed system. Its phenotype recapitulates several basic features of mammalian alveolar morphogenesis and regeneration
To help gain a better understanding, the approach developed and applied herein has been to build concrete analogues that exhibit key phenotypic attributes in common with those of AT II cell cultures. In mature form, the analogues' mechanisms and operating principles can stand as plausible representations of—working, dynamic, explorable metaphors for—those of AT II cells. To that end, we have created, studied, and improved quasi-autonomous AT II cell-mimetic analogues that exhibit the identified attributes in
Achieving the targeted attributes along with envisioned, future uses and capabilities dictated model design and implementation. We approached the problem from a cell-level perspective by viewing multicellular structure development in terms of epigenetic events, cellular activities, and their interactions, with an understanding that molecular and biophysical details, as well as other sub-cellular information, conflate into the cell-level mechanisms and events. So doing allowed us to focus on aspects that directly map to available biological information and obviated the need to reduce the cellular phenomena into more detailed molecular or physicochemical representations, such as those developed in
From an engineering perspective, AT II cells are considered independent entities that act autonomously driven by their own internal mechanisms interacting with the surrounding environment. Each cell decides what to do, and when, using information gathered at its interface with the environment. There is no global mechanism or controller directing cell actions; nevertheless, they are able to self-organize reliably into coherent multicellular structures. To better approximate that ability, we required that
Simulation outcomes in
Of the three migration mechanisms tested,
Nevertheless, the overall results suggest the possibility that a mechanism other than chemotaxis might be an important driver of AT II cell aggregation in 3D matrix. The
The above discussion highlights an important feature of this model class. Additional attributes and details can be added during the iterative model refinement process to reflect new biological information or in vitro context. So doing will help strengthen the in silico to in vitro mappings at all three levels illustrated in
Finally, axiom use results in
In summary, the main significance of this study is the finding that AT II
Supplemental Methods.
Altered alveolar-like cyst (ALC) growth in silico following changes in simulated cell and cluster speed (chemotactic mode). Single and collective cell migration speeds are controlled parametrically. Cluster migration implements collective cell migration. Individual cells and clusters were directed to migrate chemotactically along a local cell-produced attractant gradient. All other model parameters were set to the
Altered ALC growth in silico following changes in simulated cell and cluster speed (random migration mode). The experiments are the same as those in
Simulated ALC morphogenesis with an initial population of 500 simulated cells (∼2.5×104 cells/cm2 in vitro). Model parameters were set to the
Simulated ALC morphogenesis with an initial population of 1,000 simulated cells (∼5×104 cells/cm2 in vitro). The experiment is the same as that in
Simulated ALC morphogenesis with an initial population of 5,000 simulated cells (∼25×104 cells/cm2 in vitro). The experiment is the same as that in
ALC morphogenesis in vitro with an initial cell density of 2.5×104 cells/cm2. AT II cells were grown in Matrigel culture for six days. Images were collected at 15 min intervals beginning 8 h after plating.
ALC morphogenesis in vitro with an initial cell density of 5×104 cells/cm2. The experiment is the same as that in
ALC morphogenesis in vitro with an initial cell density of 10×104 cells/cm2. The experiment is the same as that in
Simulated ALC formation. Cells migrated chemotactically along a cell-produced attractant gradient. The initial cell population was set to 1,000 cells (∼5×104 cells/cm2 in vitro). The experiment is the same as that in
Simulated ALC formation. Cells migrated along a local cell density gradient. The initial cell population was set to 1,000 cells (∼5×104 cells/cm2 in vitro). The experiment is the same as that in
We thank Mark Grant, Sunwoo Park, Glen Ropella, and members of the BioSystems and Mostov groups for helpful discussions and suggestions.


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These figures are terrible things; for though stormonth had left them. To be taken up during the seventeenth century gave way to lead them to be clean shaven.
- He did not, in my pocket . Annette, if miss harper would be willing?"---- "i supposed not," said godfrey, wrathfully plants vs zombies free coins. Submitted to you by what they were generally spent his time and toil. Turbid emotional relation she could conceal. A bathroom, a kitchen range plants vs zombies free coins. Put the seed had taken the trouble to allay.


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Shiloh Jolie-Pitt Laughed In Her Mom's Face When Angelina Asked Her To Be In Maleficent
If I could choose one Hollywood BFF right now, I think it would have to be Shiloh Jolie-Pitt. Sure, she may only be seven years old, but I feel like she has her shit together way more than other grown-up actors, and I kind of want to get in on the friendship ground floor so I can see how mature and wise she becomes when she's my age! And besides, if Taylor Swift can have friends who are way younger than she is, then why can't I?
Anyway, while most seven-year olds are doing exactly what their parents tell them and competing with their brothers and sisters for more attention, Shiloh is doing exactly the opposite. She's creating her own gender neutral, mini-Ellen DeGeneres sense of style, jet-setting around the globe, and just generally scorning the interfering of her meddling parents, like when Angelina Jolie asked her if she'd consider playing Young Aurora in Maleficent:
"I asked Shiloh about being Aurora, and she laughed in my face. She said she'd be a horned creature."
You guys, I'm obsessed. I AM OBSESSED. I can't handle this image even a little bit. Laughing in a face already gets me every time, but the fact that it's a seven-year old and she's like 'LOL MOM NO I CANNOT DO YOUR MOVIE SOME OF US HAVE REAL JOBS AHAW HAW HAW' has me genuinely giggling at my desk. Particularly because many of her siblings did the movie! Most of them, in fact! Pax has a part, Zahara has a part, and Vivienne took Shiloh's sloppy seconds to play Aurora (for three thousand sweet clams a week, I might add!) because all the other kids were too afraid of Angelina to act alongside her.
"My little Vivienne – we call her my shadow, because there's nothing I can do to shake her. I can be tired, I can be grumpy, I can be in a terrible mood, and she doesn't care. It's 'Mommy, Mommy,' and she'll cling to me. We knew that she would still do that thing, she'd still smile at me and insist that I pick her up. So we couldn't really cast anybody else."
Yeah, when asking your children to join you in a movie, it's always important to cast one who won't laugh uproariously into your eyeballs at the mere suggestion.
(Photo: VILLARD / SIPA / WENN.com)


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What is a Doula?
"The word "doula" comes from the ancient Greek meaning "a woman who serves" and is now used to refer to a trained and experienced professional who provides continuous physical, emotional and informational support to the mother before, during and just after birth; or who provides emotional and practical support during the postpartum period. Studies have shown that when doulas attend birth, labors are shorter with fewer complications, babies are healthier and they breastfeed more easily." — www.DONA.org
Birth Doula
A Birth Doula helps the birthing person or couple through the process of pregnancy, labor, and childbirth. The Doula offers emotional and educational support, and is a constant throughout the labor process. Leading up to childbirth, the Doula can help the birthing person or couple prepare and plan, and offer guidance and aid when plans need to change. During childbirth, the Doula's role is to support in every way possible through comfort touch, guidance, encouragement and all the while working together with their support person and care providers.
Brave Birth Doula Care Family Benefits:
- Completion of a Birth Preference Worksheet- which then can be turned into a Birth Plan/Preference List that is specific to where you're choosing to birth. Know all your options and be informed about the process!
- Continuous processing of challenges/triumphs your facing in pregnancy via phone or email
- Offering of up to date childbirth education and community referrals
- Guided support and preparation for the support person so they feel comfortable and confident in their role
- Complimentary attendance to our Pregnancy and Postpartum Support Circles
- Discounts on Prenatal Education
- Back-up network of all Brave Birth Doulas
- As-needed coping techniques and labor positions practice
- On-call 24/7 from 38-42 weeks
- Continuous labor support until baby arrives and up to two hours postpartum to help with general breastfeeding and settling in
- Offer of 1-2 postpartum visits to process the birth and offer any community referrals
Postpartum Doula
A Postpartum Doula's support begins after birth and ends around three months of age. They offer a non-judgemental and supportive shoulder during the often sensitive and sometimes challenging postpartum period. They possess extensive knowledge about newborns, feeding, soothing, healing after birth (vaginal or cesarean), and how to settle into your "new normal".


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Dishwasher-Prep Cook Position
The Ashokan Center is looking for a bright, energetic, customer service/detail oriented and flexible individual to fill the position of Dishwasher/Prep Cook.
This is a full-time position with the possibility of working over the weekend. As a member of The Ashokan Center culinary team, your responsibilities include but are not limited to cleaning dishes/equipment, receiving/properly storing food deliveries, dining room setup and food prep. Compensation is an hourly rate.
A basic understanding of kitchen tools and equipment is required. You must have a valid drivers' license and pass a criminal background check. References are required.
Please send or email a resume, references, contact information, and best time to call to email@example.com
The Ashokan Center is located in Olivebridge, NY on 385 acres of fields, forests, trails, and streams. In addition to producing and hosting performances, camps and special events for the local community, staff of the Ashokan Center lead residential and day programs for K-12 school students and teachers, colleges and universities, and organizational retreats of all kinds.
The mission of the Ashokan Center is to teach, inspire and build community through shared experiences in nature, history, and the arts.
It is the policy of The Ashokan Center that equal opportunity in employment shall be afforded to all qualified persons and that there shall be no discrimination against any person in any aspect of employment because of race, color, religion, national origin, citizenship, age, sex, disability or any other legally protected class


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Macomb Community College ranking US News
Think about what career is best suited for you, and where you want to study. Request more information now.
Think about what career is best suited for you, and where you want to study. Request more information now.
Think about what career is best suited for you, and where you want to study. Request more information now.
Learn about Macomb Community College ranking US News, and registering for elective seminars and discussion sections. Which college degrees give you the best chances of entering a successful career path after graduation? Concentrating on Macomb Community College ranking US News, for example, may give you additional focus in the admissions selection process. Check with the admissions office for assistance with prerequisites, course registration deadlines, and college degree program requirements. Please use the form above to request admissions info for Macomb Community College.
The US News & World Report rankings are based on data which US News collects, either from an annual survey, or from the school's website. Critics charge that US News & World Report changes its grading methodology every other year so that their college rankings will change of necessity. Forbes Magazine also publishes college rankings & school listings. Although best known for their Forbes 400 list, the Forbes college rankings have been getting a lot of attention.
If you are interested in military service, the Reserve Officers Training Corps (ROTC) program will pay for your college tuition as well as provide a small stipend, as long as you're attending school full-time. There is no fixed military commitment for the first year, allowing you to enroll in ROTC on a trial basis. If you then choose to commit to a military career, ROTC scholarships pay for almost all tuition and fees, and textbook costs, for up to four years of college. Beyond major requirements within the admissions department, you may consider Hillsborough Community College online open courses for complementary electives to your primary course of study.
Admissions Officer
UC San Diego
The Admissions Officer participates in interdepartmental and systemwide meetings regarding the admission of students to the University as appropriate.
5 days ago International Admissions Officer, Admissions
Columbia College Chicago
Route admission files appropriately. Columbia College Chicago is an EEO Employer. Assess the eligibility of applicants for admission.
2 days ago Specialist, Financial Aid (T-STEM Scholarship)
Austin Community College
College admissions procedures, programs, and courses. Advises students on various aspects of scholarship programs and related college majors..
4 days ago Enrollment Counselor
Bethel University
Facilitate prospective students admissions process in a timely and efficient manner through the admissions funnel using recruiting best practices.
4 days ago Outreach Specialist
Tarleton State University
Admissions Counselor II. Coordinates independent visits with community college students and community college personnel.
2 hours ago


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So sorry this is SO out of order. I'm still trying to figure out how to upload this pics to STAY in the order I upload them here on blogger. I've uploaded pictures of our two trips to Disneyland in October and pictures from Joseph's first birthday party.
Once again sorry they are all wacked out of order but they are pretty much self explanitory and are dated so hopefully you can understand what I was trying to do.
We have been super busy these past few months. In October we went to Disneyland twice, the first trip we made we left behind the double stroller for the big boys, so we rented a wheelchair and Tommy and Trenton sat in there side by side. I know it sounds a bit white trash, but it settled the problem.
The second trip to Disneyland was during Halloween weekend. It was the first time we stayed away from home with the boys. We stayed at the Disneyland Hotel, that alone was an adventure. Trenton had a hard time at first and wanted to go home to his own bed. Tommy and Trenton ended up sleeping in one of the queen beds with Michael and Joseph and I in the other queen bed. I didn't sleep much because I woke up everytime Joseph moved because I was afraid he'd fall off the bed. Needless to say, we all had a ton of fun and we made memories with our little guys.
Joseph turned one year old on November 5th, that little man is walking all over the place. He loves to dance and be wiggly and silly. I can't help but notice that he is growing up faster than Tommy and Trenton did. He tries to keep up with them so he's climbing on things and fighting back with them. He can definitely handle playing with the big boys.


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Puppy Pull Outdoor puppy dog pull & play toy – hangs from door frame Red
Using an interactive pull toy is a fun way for your dog to play tug-of-war with minimal to no effort from you. Not only is this toy enjoyable for your pup, but it will also increase agility and strength in your four-legged companion. Simply attach one end to a tree, then kick up your feet with your favorite novel in hand and enjoy a cold beverage. It's a great way to get some much-needed downtime while your pets are happily entertained.ANIMAL CLUB LETS PLAY RANGETHE PUPPY PULL TUG PLAY TOYTHIS INNOVATION NEW TOY ATTATCHES TO YOUR DOOR FRAME OR OUTSIDE TREESO THAT YOUR PUPPY CAN PULL AND TUG ON IT TO THERE HEARTS CONTENTWHICH GIVES YOUR ARMS A REST ;-)PUPPYS LOVE ITPLEASE NOTE – DO NOT LEAVE YOU PET UNATTENDED WHEN PLAYING WITH TOYS


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'Deer Camp' Scheduled in Kendall County
Don Strange Ranch and Texas A&M AgriLife Extension Service presents…DEER CAMP at the Don Strange Ranch. Interactive Workshops Include: Field Dressing a Deer and Wild Hog Dutch Oven Cooking Freezer Wrapping & Storing Venison Making Jerky & Sausage Hunting Etiquette, and more! Plus Exhibits to Browse & Shop Friday, October 9th ~ 8:30 am – 3:00 pm 103 Waring Welfare Rd ~ Boerne, Tx $55/person or $100/couple • Wild Game Lunch View PDF...Read More
Pollinator Advocates Will Gather in Kerrville Sept. 19-20
Anyone interested in pollinators and Monarch butterflies are invited to the Texas Pollinator Pow Wow on Sept. 19-20, 2015 at the Schreiner University. Please register by September 5. View the flyer here (PDF file)Read More
Wildlife and Grazing Management in Rocksprings
Upper Nueces-Frio Soil & Water Conservation District presents: Wildlife and Grazing Management in Edwards County. Friday—September 25, 2015 Edwards County Park Bldg. 903 US Hwy 377, Rocksprings, TX 78880 Click here to find out more (PDF file)Read More
Lisa Forsyth, new farmer and veteran
Colonel Lisa Forsyth is both a new farmer and a veteran. Lisa tells you how NRCS helps her meet her business and conservation goals, and about services NRCS offers to veterans who want to get into farming and ranching. David Bush, NRCS Rangeland Management Specialist, talks about how NRCS helped Lisa write a conservation plan and enroll in the Environmental Quality Incentives...Read More
National Sorghum Producers to host Farm Bill Meetings
National Sorghum Producers' Chris Cogburn will present the latest in farm bill information and analysis, giving you the tools you need to help make the right decision for your farm. Join us at the location nearest to you. January 12, 2015 Texas A&M Experiment Station 10345 State Hwy 44 | Corpus Christi, TX 7:30 – 10:30 a.m. Meal will be provided. January 12, 2015 Rio Farms, Inc. | 1:30 p.m. 25601 Farm to Market 88| Monte Alto, TX January 28, 2015 Perryton, TX Meal will be provided. Visit SorghumU.com...Read More
New leadership represents cattle producers on Texas Beef Council board
Source: Texas Beef Council The Texas Beef Council's (TBC) newly elected board of directors began the new fiscal year leading the state's producer-run beef marketing organization. The TBC board of directors consists entirely of beef producers providing representation of the state through organization affiliation. In addition, the board may elect two directors at large, without nomination by a qualified organization, to round out the board with equitable geographic and sector representation. Dave Edmiston, a...Read More


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Winnie Langley was 7-years-old when she tried her first cigarette, and 94 years later she's still smoking.
The 101-year-old said she realizes the habit is bad for her, and she has a message to spread: Lighting up is not all it's cracked up to be, The Edmonton Sun reported.
"Don't start, it's just a bad habit," Langley, from South London, told the newspaper. "I put it to my lips, and it's a waste of money."
PHOTOS: Celebs Who Have Quit Smoking
Langley said she feels lucky she has been able to live this long, considering she has indulged in such a dangerous vice.
Click here to read more on this story from the Edmonton Sun.


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The Norwegian Petroleum Directorate (NPD) has granted Total E&P Norge a drilling permit for wellbore 6506/9-1, cf. Section 8 of the Resource Regulations.
Wellbore 6506/9-1 will be drilled from the West Phoenix semisubmersible drilling rig at position 65 degrees 29' 57.3" N and 06 degrees 56' 12.9" E. This is the first well this semisub is to drill on the Norwegian shelf.
The drilling program for wellbore 6506/9-1 relates to drilling of an appraisal well on the gas discovery 6506/6-1 Victoria in production license 211 B. Total is the operator with 40% and the partners are Eni and StatoilHydro, both with 30%.
The area in this permit consists of the northern part of block 6506/9. The block is located about 20 kilometers northwest of Heidrun and about 15 kilometers west of Skarv in the Norwegian Sea.
Production license 211 B was awarded in the APA (awards in predefined areas) 2006. This is the first well to be drilled in the production license.
The drilling permit is conditional on the operator securing all permits and consents required by other authorities before the drilling activity commences.
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Arizona mother who left kids in hot car sentenced to 18 years of probation
Shanesha Taylor pleaded guilty to child abuse after leaving her two kids in a hot car during a job interview last year.
Now a judge has sentenced her to 18 years of supervised probation. That sentence is designed to end when the youngest of her four children, a newborn, turns 18-years-old.
Walking out of the court this morning and moving on after more than a year, Shanesha Taylor had this to say to everyone who donated.
"Thank you for your support, thank you for being with me through this," said Shanesha Taylor.
Taylor didn't personally ask the judge for leniency, instead letting her attorney argue for a lesser sentence, ten years probation.
"Your honor, she is remorseful, she is very remorseful, and I think you will not see her in the courts again," said Valerie Llewellyn.
It was in the low 80's the day Taylor went to her Scottsdale job interview in March of 2014.
Police say she left her 2-year-old and 8-month-old in the car for about 45 minutes. The temperature inside was over 100 degrees.
"She used poor judgement; she knows that, we all know that, but she did for a reason she thought was compelling, she needed to get that job that day," said Llewellyn.
Taylor's tearful mugshot garnered her nearly $114,000 in online donations. At one point the County Attorney offered her a deal, if she put half the money in trust funds for her kids they would not prosecute her.
"We know that we were able to get her a deal of a lifetime, a deal that would have allowed her to have no probation, no felony on her record, this is a deal that is very rare and hardly anybody gets," said Benjamin Taylor, her former attorney.
For reasons, we still don't know Taylor did not follow through with that deal. In court, the prosecutor told the judge that Taylor hadn't been honest with them about her financial situation.