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Obama calls for more Myanmar reform on Asian tour
BANGKOK, Thailand (UPDATED) - President Barack Obama flexed US power in Asia Sunday, November 18, on a regional tour that will make history when he lands in Myanmar, calling on its leaders to step up their startling political reform drive.
Obama touched down in Air Force One in Bangkok, sending a message that relationships like the six-decades-old treaty alliance with Thailand will form the bedrock of US diplomacy as the region warily eyes a rising China.
Obama will on Monday, November 19, become the first sitting US president to visit formerly isolated Myanmar. He will praise President Thein Sein for ending a dark era of junta rule, but also prod him to go much further towards genuine democracy.
Then, in a stark illustration of how far Myanmar has come, the US leader will stand side-by-side with democracy icon Aung San Suu Kyi at the lakeside villa where his fellow Nobel laureate languished for years under house arrest.
Speaking in Thailand on the eve of the visit, Obama praised Myanmar's reforms but urged the regime to do more.
"President Thein Sein is taking steps that move us in a better direction," he told a press conference. "But I don't think anybody's under any illusion that Burma's arrived," he added, using the country's former name.
"The country has a long way to go. I'm not somebody who thinks that the United States should stand on the sidelines and not want to get its hands dirty when there's an opportunity for us to encourage the better impulses inside a country."
After a 19-hour journey from Washington, Obama first paid homage to Thailand's ancient history with a private tour of the Wat Pho temple which is famed for a huge, golden statue of a reclining Buddha.
"What a peaceful place," US Secretary of State Hillary Clinton told the president, who remarked that they were having a "treat" because the normally crowded tourist attraction had been cleared for their visit.
Then Obama called at Siriraj hospital in Bangkok for an audience with revered King Bhumibol Adulyadej, seen as a symbol of continuity for a kingdom with a turbulent political past.
Obama and Clinton greeted and shook hands with the frail monarch, who turns 85 next month.
After talks with Thai Prime Minister Yingluck Shinawatra focusing on trade, regional politics, counter-narcotics issues and terrorism, Obama held a joint press conference with her.
His visit to Asia, coming just 12 days after he won re-election, is the latest manifestation of his determination to anchor the United States in a dynamic, fast-emerging region he sees as vital to its future.
The Hawaii-born US president is making his fifth official visit to the region, where he spent four years as a boy in Indonesia, and is diving back into foreign policy after a year spent on the campaign trail.
The stop in Myanmar will be rich in symbolism, not least when he gives a speech at Yangon University, where restive students stoked revolt repeatedly over five decades of military rule.
The White House hopes Obama's visit to Myanmar will boost Thein Sein's reform drive, which saw Suu Kyi enter parliament after her rivals in the junta made way for a nominally civilian government -- albeit in a system still stacked heavily in favor of the military.
Some human rights groups said Obama should have waited longer to visit, arguing that he could have dangled the prospect of a trip as leverage to seek more progress such as the release of scores of remaining political prisoners.
But officials say that Obama will encourage the regime to double down on more reform, and that his influence could be important at a crucial moment in Myanmar's emergence from decades of isolation and repression.
The United States on Friday scrapped a nearly decade-old ban on most imports from the country, after earlier lifting other sanctions.
But it continues to call for the release of scores of political prisoners still in Myanmar's jails, as well as an end to sectarian bloodshed between Buddhists and Muslims in western Rakhine state.
On Monday Obama will fly to Cambodia, and a likely tense encounter over human rights with Prime Minister Hun Sen, ahead of the East Asia Summit, the main institutional focus of his pivot of US foreign policy to the region.
On the summit's sidelines, Obama will meet China's outgoing premier Wen Jiabao and Prime Minister Yoshihiko Noda of Japan, whose relations with Beijing have frayed because of rival territorial claims. - Stephen Collinson, Agence France-Presse


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All packed up for tomorrow, aside from my riser that I'm setting up for all the bands to use today
All packed up for tomorrow, aside from my riser that I'm setting up for all the bands to use today
A few shots of 2 of the bands I helped set up... I didn't think to take pics of the first band
It rained pretty hard earlier in the day and chased a lot of people away, but it still went over well
Some pics of my setup
A couple Facebook live videos my wife took. She didn't have the steadiest of hands.... Sorry lol
This is The John Edwards Band. 1st song is an original called 333. It's the most rock sounding song we do, the others are closer to country or I guess lighter rock? Second song is wagon wheel.
This video is of Plan B. The first song is The Stake. The second song is an original called Elizabeth. I forgot how to play it at first but I recovered lol. I had some issues but I think the gig went very well. I had a blast being drum tech and playing.
Oh yeah, I dropped the ball bad, I have a gig coming up this Friday that I just found out about last night lol.... Oops
This is going to be a long night... gotta work till 5 then get ready and head straight to the venue. We don't usually have gigs on Friday because of this, I'll just have to suck it up lol.
Website for the New Cumberland River Fest. They have us labeled as Plan B with John Edwards, but this has been scheduled for a while and probably before we made the John Edwards Band the official name. Also time changed to 2:30-4:00 instead of 3:00-4:30 (changed on the front page)
That is one reason I am kinda excited for this River fest gig. It's 2:30-4:00 on a sunday afternoon, short mid day gig so I won't be super tired at the end of it. And since it's a John Edwards band gig I'll only be taking a 4 piece with maybe 2 crashes, though my ride sounds so damn good as a crash I might go with just one crash and maybe boom a splash into the mix with a quick boom. I just can't leave it alone I guess lol.
Now I'm trying to think If I want my popcorn snare and tambourine pedal or not... hmm....... and Probably will go without my in ears. I'm putting way to much thought into this right now while at work LOL


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National Museum of Funeral History
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Flannery O'Connor: Faith and Literature
How can we see the life and faith of Flannery O'Connor in her short stories?
Solution Preview
In "Revelation," I feel like O'Connor's strong Roman Catholic faith and sense of traditional values and manners permeate, especially through the character's symbolic name, "Mary Grace." In addition, the character of Ruby and her redundant references to God's goodness definitely echo the sentiments of O'Connor's faith. The title itself, "Revelation," also evokes the author's religious fervor.
The ending of the story is especially evocative as it summons a hell and heaven which stalk the protagonist. It also fits with O'Connor's literary preference to mix the religious with a strong sense of the grotesque: "She saw the streak as a vast swinging bridge extending upward from the earth through a field of living fire. Upon it a vast horde of souls were rumbling toward heaven [along with] battalions of freaks and lunatics shouting and clapping and leaping like frogs."
I also detect strong evidence of the author's personal life as it also filters through the story since it deals with Southern ideologies. These worldviews also characterized O'Connor's life. For example, Ruby Turpin's demonstration of superiority, "like a monumental statue coming to life, "correlates with the setting and era of the author's life and upbringing. Ruby's militant Southern pride also aligns with O'Connor's upbringing and life as well in this story.
This limited worldview is expressed by her comments, ...
Solution Summary
Flannery O'Connor's short stories are examined to demonstrate faith themes. Textual evidence is used.


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The Company:Our client is a leader in power and automation technologies that enable utility and industry customers to improve performance while lowering environmental impact. They operate in around 100 countries employing over 145,000 people.The Role:To provide administration/coordination support to the Rampion Site project team based at Twineham site whilst ensuring company policies and procedures are implemented and maintained with strict deadlines met. 1. Support of project team 2. Proactively support in the filing and control of site documentation received from design office and utilised at site. Ensuring correct filing sequence, control of issue and return. 3. Preparation of minutes 4. Progressing of site materials including skips, water supplies, etc., coordinating with Office SCM. 5. GRN of deliveries, control of delivery notes between site and Project SCM 6. chase Stone for outstanding responses 7. Preparation of daily reports in suitable detail. 8. Assist with monthly reports 9. Daily photo's named and uploaded 10. Ensure all document is uploaded on time Act as a central point of contact and provide administrative/coordination support to Site Project Team. Assist with preparation of Internal and external minutes of meeting and reports in accordance with Company policy and procedure Assist in purchases of stationary and other associated site materials Maintain electronic and paper-based filing systems Ensure RIVO reporting is maintained for near misses and hazards, TQs and NCRs Document Control and Reporting Issues. Daily Reporting Spreadsheets Using ABB Internal databases (Training Provided) Managing all welfare and office facilities Liaising with ABB internal purchasing Support Site Team with Administration Control Of Goods Inwards PaperworkEssential Skills / Qualifications:Excellent administration skills An ability to work within a team environment and able to take instruction Excellent verbal, written and visual communication skills to interact with all levels of a business both internally and externally. Good IT knowledge, using a variety of standard software packages. Experience of working with databases essential Methodical thinker with attention to detail Ability to work to tight deadlines Comfortable in Construction Environment Process Driven and Disciplined Able to work under own initiative Other office related duties when requiredAbout Fircroft:Fircroft has been placing people in specialist technical industries for approaching half a century, focusing on mid to senior level engineers for contract and permanent roles worldwide. By applying for this job you give consent for Fircroft to contact you, via email & telephone, to discuss your application along with future positions and Fircroft's services.
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Supermicro - Power adapter - 60 Watt - United StatesItem#: 13981805 | Model#: MCP-250-10117-0N
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Supermicro - power adapter - 60 Watt Product Details
Device Type: Power adapter - external
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This film tells the story of notorious American writer Truman Capote and his journey in composing his most celebrated book 'In Cold Blood', a non-fiction account of the brutal murders of the Clutter family in Kansas in 1959.
Indeed, to many filmgoers this narrative may seem all too familiar to one of last year's most memorable films, 'Capote'. It was directed by Bennett Miller and earned Philip Seymour Hoffman Best Actor at the Oscars for his portrayal of the famed novelist.
To be blunt, 'Infamous' tells the same story and it is quite a wonder that both films came into being within 12 months of each other. In assessing director Douglas McGrath's 'Infamous' it is difficult to refrain from alluding to its predecessor.
They both introduce the protagonist in his high society abode and follow him on his journey to Kansas to investigate the murders. They both show the development of his relationship with murderer Perry Smith (Craig) and the agonising moral dilemma he faced inside his own head with not wishing his friend to die and his thirst to finish the story.
However, there are differences that set these films apart and the devil is in the details.
The casting of Toby Jones as Truman Capote is one such nuance. Although he looks and sounds the part, he fails to encapsulate either the spirit or the emotional excursion of the writer. For the most part he comes across as more annoying than charismatic or engaging.
It is not his liability alone, as the film itself does little to establish Capote as a formidable character. Too many dramatic tensions are all too often disrupted between scenes with lacklustre comedy. Indeed, it is here where the film seems to metaphorically fall between two stools.
'Infamous' is based on a biography of Truman Capote in which many of his high society friends of the time give their thoughts on the writer and unfortunately the film is interrupted with mock interviews from the characters throughout.
Although this film pales in comparison to its predecessor, it still has a few redeeming qualities. Sandra Bullock puts in an excellent understated performance as the novelist Harper Lee and Daniel Craig keeps the audience on his side for the most part in the role of Perry Smith.
However, the tone of the film does not fit well with the subject and one certainly feels the anguish felt by Capote in wanting this story to come to an end.
David McDonnell


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2017 Executive Sponsors
2017 Associate Sponsors
2017 Technology Sponsors
2017 Exhibitors
2017 Soapbox Sponsors
2017 Media Partners
2017 Sponsors / Exhibitors
2017 Executive Sponsors
3M Drug Delivery Systems is a global leader and innovator for inhalation and transdermal drug delivery. Between drug discovery and commercialization, we offer: Innovative and proven technology; Global regulatory expertise; Commercial manufacturing; Broad range of customizable system components and product development services.Our expertise increases your opportunity for success. Visit www.3m.com/dds.
BD is a medical technology company that serves healthcare institutions, life science researchers, clinical laboratories, industry and the general public. BD designs, manufactures and sells a broad range of medical supplies, devices, laboratory equipment and diagnostic products.
BD Medical – Pharmaceutical Systems is the partner of choice for the pharmaceutical industry. With innovative prefillable syringes, self-injection systems, safety systems and needle technologies, we offer an extensive selection of solutions designed to protect, package and deliver drug therapies. Our products reflect more than a century of experience and market knowledge, and our experts provide comprehensive system-based service and full product solutions. For more information, visit us at https://bd.com
2017 Associate Sponsors
Insulet Corporation is an innovative medical device company based in Billerica, Massachusetts. Insulet Corporation designs and manufactures the OmniPod Drug Delivery and Diabetes Management Systems. The OmniPod is an easy-to-use, programmable, body-worn, subcutaneous infusion pump used to treat diabetes and infertility. For more information, visit www.insulet.com.
iO life science, formerly LUNAR Lifesciences, partners with healthcare providers to deliver strategy, design and engineering services for medical system and device development with compliance at the core. By unveiling user needs and key value propositions at the onset, we help clients to innovate in a meaningful way.
Creative expression and design-engineering cross fertilization are central to our product development success. By engaging seasoned worldwide resources, iO life bridges award winning, user centric design with cutting edge technology for first rate product development at considerable value.
This global approach coupled with our proven risk-managed process allows iO life to scale effectively and reduce time to market. Ultimately, we provide patients and providers with solutions that adapt to individual lifestyles and deliver measurable outcomes. Start a project at: iolifescience.com
At Pfizer, we apply science and our global resources to bring therapies to people that extend and significantly improve their lives. We strive to set the standard for quality, safety and value in the discovery, development and manufacture of health care products. Our global portfolio includes medicines and vaccines as well as many of the world's best-known consumer health care products. Every day, Pfizer colleagues work across developed and emerging markets to advance wellness, prevention, treatments and cures that challenge the most feared diseases of our time. Consistent with our responsibility as one of the world's premier innovative biopharmaceutical companies, we collaborate with health care providers, governments and local communities to support and expand access to reliable, affordable health care around the world. For more than 150 years, Pfizer has worked to make a difference for all who rely on us. To learn more, please visit us at www.pfizer.com.
PharmaCircle is a leading provider of global information and analytics on drugs, biologics and combination products in all stages of development. PharmaCircle's premier database delivers an in depth view into drug development and innovation, examining more than 160,000 pipeline programs and marketed products, and the business portfolios and transactions of nearly 16,000 companies worldwide. PharmaCircle also provides expert analyses on more than 6,000 drug delivery technologies and devices. For more information visit: www.pharmacircle.com
2017 Technology Sponsors
Adare is a global specialty pharmaceutical company focused on developing innovative products that can improve the lives of patients whose treatment needs are not fully addressed by current medications. Over 40 products incorporating Adare taste-masking, customized drug release, and bioavailability enhancement proprietary technologies have been commercialized around the world. Visit www.adarepharma.com
Aprecia, the leader in 3DP pharmaceutical manufacturing, is a technology partner dedicated to taking medicine to its fullest potential through truly novel dosage forms. Aprecia's ZipDose Technology produces high-dose, rapidly-disintegrating oral dosage forms across multiple therapeutic categories. Visit www.aprecia.com to discover how 3DP manufacturing can optimize your brand and pipeline.
Bespak, a Consort Medical company, is a global leader in the development and manufacture of complex drug delivery devices, including innovative Syrina VapourSoft injectable devices, respiratory, nasal and ocular systems. Bespak's expertise and capabilities have contributed to the industrialisation of some of the world's leading medical devices. Visit us at www.bespak.com or contact us: email@example.com
For 20 years, BIOCORP has been developing and producing medical devices for the pharmaceutical industry, enhancing drug reconstitution, packaging and delivery. Recognized for its expertise in device R&D, BIOCORP has incorporated software development capacities to offer connected drug delivery systems in order to meet the evolving needs of patients and improve treatment adherence. Learn more at www.biocorp.fr.
Cambridge Design Partnership is a leading product and technology innovation partner with offices in Cambridge, UK and Palo Alto, USA. We are specialists in drug delivery device design, development, prototype and short-run manufacturing, working for some of the world's largest companies. Our experts in engineering, human factors and industrial design are able to take combination products through a full design cycle and submission, to enable you to launch a product that is customer focused and commercially effective. Certified to ISO13485/9001. Learn more about us at www.cambridge-design.co.uk
Capsugel – now a Lonza company – designs, develops, and manufactures a wide range of innovative dosage forms for the biopharmaceutical and consumer health and nutrition industries. Our unique combination of science, engineering, formulation and capsule expertise enables our customers to optimize the bioavailability, targeted delivery and overall performance of their biopharmaceutical and consumer health and nutrition products. We partner with more than 4,000 customers in over 100 countries to create novel, high-quality and customized solutions that align with our customers' evolving needs and benefit patients and consumers. Learn more at www.capsugel.com.
Credence MedSystems is a medical technology company focused on delivering medications safely for the benefit of patients, caregivers and partners. The Companion Safety Syringe System was born from Credence's philosophy of Innovation Without Change. The Companion offers our pharmaceutical partners a simplified path to commercialization of a best-in-class delivery system by providing passive safety and reuse prevention while using existing primary package components. The Companion is available in luer needle, staked needle and dual chamber reconstitution configurations. In all cases, the user performs the injection, receives end-of-dose cues and then the needle automatically retracts into the syringe, which is disabled. Visit us at www.credencemed.com.
Cristal Therapeutics is a clinical stage company developing nanomedicines for the treatment of cancer and other diseases. The company's product candidates are based on its proprietary CriPec® polymeric platform, which enables the design of customised nanomedicines. CriPec® -based products have the potential to provide enhanced efficacy and reduced side effect profiles, thus offering improved disease treatment. The lead product, CriPec® docetaxel, is in clinical phase Ib studies for the treatment of solid tumours, while several other products are in preclinical development. Learn more at http://cristaltherapeutics.com.
DALI Medical Devices ("DALI") was founded in 2003, bringing over 20 years of experience in developing drug delivery devices all the way from concept through commercialization. DALI has developed a family of Flexi-Q next-generation auto-injectors in collaboration with Elcam Medical/E3D. The company is developing an innovative new line of customizable unique solutions: Safe Auto-Needles (SANs), for use with any type of syringes/vials/cartridges – for major pharma, generic and bio-similar companies. Learn more at www.dalimed.com.
DelSiTech is a drug delivery and drug development company that works with its partners to turn their active agents into novel drug products. The company's technology, Silica Matrix, is a biodegradable, biocompatible controlled/extended release platform for non-oral dosage forms. Silica Matrix is suitable for delivery of small molecules and biologics as well as offering thermostability and abuse deterrent properties. DelSiTech also develops its own supergeneric drug products to address significant unmet medical and commercial needs. 1308 is a 3 month hepatitis B product that will enter Phase I this year. Learn more at www.delsitech.com.
DS Technology is your innovative partner for bringing your creative product rapidly to market. In close cooperation with you we create bespoke superior solutions on the basis of your input and your needs. You benefit from our wealth of experience in pharmaceutical processes, a multitude of manufacturing technologies and a careful selection of the most suitable materials. Our focus is on you, your product and your success. Learn more at http://d-s.technology/en.
Elektrofi is a formulation company working on high-concentration, low-viscosity biologics for subcutaneous injections. Our Elektroject™ platform will enable drug manufacturers to more easily develop breakthrough therapies, dramatically improve the convenience of administration, and improve patient access through affordability. Learn more at www.elektrofi.com.
Enable Injections is a late-stage startup company that has developed a disposable body-worn bolus injector to deliver high viscosity/volume payloads up to 50 ml. The system uses a standard vial, cartridge or syringe container closure, and can automatically mix lyophilized solutions. Founded March 2010, the company has R&D, operations and manufacturing facilities in Cincinnati, Ohio. Visit us at enableinjections.com.
Evonik Industries, a global leader in specialty chemicals, provides drug delivery technologies, API manufacturing, intermediates, ingredients for nutraceuticals, amino acids and derivatives. Drug delivery technologies include formulation development services, solubility enhancement, functional excipients, bioresorbable polymers and GMP manufacturing for oral and parenteral formulations. Advanced delivery technologies for extended-release parenterals are offered for small molecules, peptides, proteins, antibodies, and nucleic acids. Learn more at www.evonik.com.
Exicure is a clinical stage biotechnology company developing a new class of immunomodulatory and gene silencing drugs against validated targets. Our 3-dimensional, spherical nucleic acid (SNA™) architecture unlocks the potential of nucleic acid therapeutics in multiple organs. Our lead programs address diseases from inflammatory disorders. Learn more at www.exicuretx.com.
Gerresheimer is a leading global partner to the pharmaceutical and healthcare industry. With our specialty glass and plastic products, we are a highly versatile contract manufacturer of custom drug delivery devices, as well as glass and plastic primary packaging containers. We have worldwide operations in Europe, North America, South America and Asia, employ roughly 10,000 employees and generate approximately $1.5 billion in revenue. Our comprehensive product portfolio includes pharmaceutical packaging, diagnostic and medical technology products and complex, customer-specific products for the safe and simple administration of medicines, such as: insulin pens, inhalers, lancing devices, medical lab test systems, prefillable syringes, injection vials, ampoules, bottles and containers for liquid and solid medicines with closure and safety systems. In regards to our drug delivery system and medical device capabilities, we are experts in product design; product and process development; IP management; regulatory affairs; mold flow simulations; mold design; mold making; prototyping; small batch and large scale production in ISO Class 7, 8 and 9 clean rooms; DFM/DFA; manual assembly and full automation; drug handling; micromolding; multi-component injection molding; decorating and much more. Let Gerresheimer help you decrease project risk and increase your product's speed to market today! Visit us at www.gerresheimer.com
Halozyme focuses on developing and commercializing novel enzymatic therapies that target the tumor microenvironment or facilitate drug delivery. Our proprietary product, the ENHANZE™ drug delivery platform, supports strong, value-driving partnerships with leading pharmaceutical companies including Roche, Shire, Pfizer, Janssen, AbbVie and Lilly. The ENHANZE™ platform has sales in 50+ countries through three product approvals. Learn more at www.halozyme.com.
Infuseon Therapeutics, Inc is developing a suite of medical devices that deliver therapeutics directly to tissue. The company's first 510(k) approved device is the Cleveland Multiport Catheter™ (CMC) system, which uses convection enhanced drug delivery to administer therapeutics to the brain. Infuseon is completing pilot clinical studies with the CMC to treat glioblastoma and continues to build its drug delivery platform strategic alliances and development of additional delivery platforms. Visit www.infuseontherapeutics.com.
iCeutica's proprietary SoluMatrix™ Fine Particle Technology creates sub-micron sized drug particles which dissolve rapidly in vivo and can increase oral bioavailability, reduce food effects, and minimize PK variability. Additionally, with superior formulation development capabilities, iCeutica provides our pharmaceutical partners with a cost-effective and reliable pathway to success. Learn more at www.iceutica.com.
InnoCore Pharmaceuticals is a biopharmaceutical drug delivery company specialized in the development of complex parenteral sustained release formulations. By using our proprietary biodegradable polymers we can make microspheres, erodible gels and solid implants resulting in long acting and minimally invasive drug delivery products of small, medium sized (peptides) and large (proteins, antibodies) drug molecules. Learn more at www.innocorepharma.
Intract Pharma is a licensing and product development company offering proprietary, state-of-the-art oral drug delivery technologies and specialist gastrointestinal models for product innovation. Having successfully developed advanced formulations for small molecules, biopharmaceuticals and live biotherapeutic products, Intract can establish the optimal pathway from early pre-clinical screening through to clinical manufacture. Learn more at www.intractpharma.com.
LayerBio, Inc is an early-stage biotechnology company developing novel drug products based on its proprietary LayerForm™ delivery platform to address unmet needs for dermatology, wound care and surgical applications. Learn more about us at www.layerbio.com.
Leon-nanodrugs GmbH (Munich) is a nanotechnology-based drug development company focused on development of novel oral and parenteral pharmaceutical formulations and innovative drug combinations. Leon's proprietary MJR® Technology platform provides a solution to overcome one of the key issues of most marketed therapeutics, poor water solubility, a pre-requisite for drug uptake into the body. Leon-nanodrugs has established CDMO partnerships in Europe and the US to enable access to key international markets. Leon's first own product developed based on the MJR® Technology is planned to be submitted for Marketing Authorization in 2017. Leon-nanodrugs offers access to the next generation nano formulated drugs with added patient benefits and economical values for its partners and shareholders. Learn more at http://leon-nanodrugs.com.
Mitsubishi Gas Chemical does business in a wide range of fields, from basic chemicals to fine chemicals and functional materials. We have recently developed multilayer plastic vial and syringe for oxygen sensitive drugs like biologics. Although the product is made of plastic, it has achieved glass-like oxygen barrier. Learn more at http://www.mgc.co.jp/eng
Nemera is a world leader in the design, development and manufacturing of drug delivery devices for the pharmaceutical, biotechnology & generics industries.
Nemera's services and products cover several key delivery routes: Parenteral (auto-injectors, pens, safety devices & implanters), Ophthalmic (multi-dose, preservative-free eyedroppers), Nasal, buccal, auricular (pumps, valves and actuators for sprays), Inhalation (pMDIs, DPIs), Dermal and transdermal (airless & atmospheric dispensers). Nemera leverages decades of manufacturing and development experience in the device segment from full development of standard innovative products, such as the passive safety device for pre-filled syringes Safe'n'Sound®and the 2-step auto-injector Safelia®, to pure contract manufacturing, through customized solutions. Learn more at www.nemera.net.
NovaFlux, Inc, a Medical Technology Company, is well known and respected among the science and healthcare communities for our dedication and commitment to developing disruptive medical technologies and technology platforms leading to the creation of medical devices designed to solve some of the most complex & threatening medical problems in today's global healthcare industry. Learn more about us at www.novaflux.com.
Oakwood is focused on the design, development, and aseptic manufacturing of sustained-release injectable microsphere products. We partner with companies in need of formulation development of their own products into sustained-release injectable form or contract manufacturing of their injectable drug. Oakwood has expertise in development of sustained-release injectable products using our patented microsphere technology. With our state of the art FDA approved cGMP aseptic manufacturing facility, Oakwood provides long term full-service supply and testing of aseptic injectable products to partners– from clinical trial material to commercial product. Learn more at www.oakwoodlabs.com
Ocular Therapeutix, Inc. (NASDAQ: OCUL) is a biopharmaceutical company focused on the development manufacturing and commercialization of innovative ocular therapies using its proprietary hydrogel platform. Our product pipeline candidates utilize the hydrogel technology to provide differentiated drug delivery solutions that are designed to greatly reduce the complexity and burden of current regimens. Learn more at www.ocutx.com.
Phillips-Medisize, a Molex company, is a technology-based provider of outsourced design and manufacturing services, with a significant business in the drug delivery space, as well as, single-use surgical medical devices, and therapeutic products. The company has expertise in high-speed manufacturing and automated inspection technologies. With early engagement in the design process, customers can expect accelerated speed to market for the products they chose to outsource. For more information, visit www.phillipsmedisize.com.
Phion Therapeutics Limited has developed a peptide nanoparticle for drug delivery that can deliver nucleic acids and other anionic compounds into tumors anywhere in the body at over a 30-fold the concentration relative to normal or healthy cells. Learn more at www.phiontx.co.uk
Phosphorex is a provider of customized drug delivery solutions, specializing in sustained release, targeted delivery and solubility enhancement. Our service offerings include drug encapsulation in microspheres and nanoparticles, solid dispersion, micronization and nanosizing, with aseptic processing and cGMP manufacturing capabilities. We support all stages of drug development from proof of concept to clinical trials. For more information, please visit www.phosphorex.com.
PolyPid Ltd. is a clinical stage biopharmaceutical company developing products based on its proprietary PLEX™ technology platform. PLEX™ is revolutionizing medicine by enabling localized, controlled and prolonged therapeutics. PLEX™ based products have demonstrated an excellent performance in clinical studies introducing best in class drugs for Surgical Site Infection management. Learn more at www.polypid.com.
Portal Instruments is developing and commercializing a highly innovative needle-free drug delivery platform technology to transform the administration of medicines and improve the patient experience for chronic diseases. Portal's needle-free delivery technology is derived from research at MIT and enables the administration of high viscosity biologic drugs with significantly less discomfort and without the anxiety of handling needles. Using precise pressure technology, the injection is administered through the skin via a jet the size of a strand of hair, ensuring optimal comfort. Real time tracking and reporting sets a new standard for interactivity between the patient and care teams, monitoring adherence and potentially improving patient outcomes. For more information, visit www.portalinstruments.com.
pSivida is a specialty pharmaceutical company focused on the development of innovative miniaturized, sustained-release drug delivery products and technologies to treat serious, debilitating diseases of the eye that can lead to blindness. The dedicated team of scientists at pSivida has developed three of the only four products approved by the FDA for the long-term, sustained-release delivery of drug to treat chronic back of the eye diseases. For more information, visit www.psivida.com.
Quantex is the innovative leader in single-use disposable pump technology. We have a catalogue of single-use pumps and also provide a design and development service for custom applications. Our engineers and designers are on hand to provide design expertise throughout the development programme and assistance into volume production. Quantex & Vernay have formed a strategic partnership to bring single-use precision pumps to the flow control market. In addition to performing a business development role Vernay can support the volume manufacture of Quantex pumps. Visit our websites to learn more about Quantex and Vernay.
Sensile Medical is a leading company in the area of micro-pumps and patch-pumps. These pumps are increasingly being used to enable Large-Volume Sub-Cutaneous delivery of modern biotech and pharmaceutical products for self-administration by patients. Sensile Medical solutions utilize electronically controlled rotary piston pump technology for highly accurate dosing regimens, enabling a broad range of drug delivery options. Founded in 2004, Sensile Medical is located in Haegendorf, Switzerland. Learn more at http://sensile-medical.com.
Serina Therapeutics, Inc has developed a patented drug delivery polymer technology based upon the water soluble polymer poly(2-oxazoline), or POZ™. We are developing a pipeline of proprietary and partnered programs applying this platform to cancer, pain, refractory epilepsy and movement disorders. Our most advanced program is SER-214, which has completed Phase I development in patients with Parkinson's disease. SER-214 is a once-weekly subcutaneous injection that delivers the potent dopamine agonist rotigotine continuously, providing continuous dopaminergic stimulation. SER-214 will be advanced into Phase II development for both Parkinson's disease and restless leg syndrome in 2017-2018. Two pipeline programs are scheduled to enter the clinic in 2018. SER-226/227 is a long-acting POZ-buprenorphine conjugate that is being advanced for post-operative pain with a target product profile of 3-7 days of analgesia. SER-228/229 is a POZ-cannabidiol conjugate that is being advanced as a once-weekly injection for refractory epilepsy and pain, as well as many other potential indications.
SMC Ltd. provides global contract manufacturing solutions of single-use devices for the pharmaceutical, medical and diagnostics industries. SMC provides full product services from initial concept through the final packaged device; including: program management, design and development, product manufacturing, clinical manufacturing, electronics integration, and global supply chain management. Visit www.smcltd.com
Founded in 1949, Stevanato Group is committed to create systems, processes and services that guarantee the integrity of parenteral medicines. It comprises two operational divisions dedicated to serve the pharmaceutical industry: Pharmaceutical Systems with Ompi specialized in glass primary packaging and Balda, focused on specialty plastics and delivery devices; Engineering Systems with Spami, Optrel, InnoScan and SVM, specialized in glass processing, inspection systems, assembly and packaging solutions. These two divisions enjoy a close, synchronous relationship, featuring daily exchanges which ensure that Stevanato Group has complete control over the entire production process. The Group also benefits from the SGLab activity that provides technical and analytical services on the potential interaction between drug and container. Visit www.stevanatogroup.com.
Suono Bio, Inc is developing breakthrough technology to enable ultra-rapid delivery of therapeutics and macromolecules across tissues without the need for reformulation or encapsulation. Preclinical studies have demonstrated the capacity to deliver small molecules, proteins, vaccines, and nucleic acids locally to specific tissues such as the gastrointestinal tract, as well as systemically. Learn more at www.suonobio.com.
Vaxess is developing next-generation immunotherapies and vaccines on the MIMIX sustained-dermal delivery platform. "Infection mimicry" via MIMIX boosts antibody and T-cell responses 10-100x, driving efficacy to previously unobtainable levels. This not only revives weakly immunogenic proteins, peptides, mRNA, etc, but also enables unique products like single-dose, self-administered vaccines. Learn more at http://vaxess.com.
West works side-by-side with its healthcare partners from concept to the patient, designing and manufacturing packaging, diagnostic and delivery systems that promote efficiency, reliability and safety. West leads the way with cutting-edge technologies and quality systems, a thorough understanding of global regulatory compliance, and an unmatched knowledge pharmaceutical product testing, development and packaging. Learn more at www.westpharma.com.
Windgap Medical is a specialty pharmaceutical company leveraging its miniature auto-injector platform to automate the rehydration and delivery of powdered drugs. Its small size and "two-steps-to-inject" operation reduces the time and complication with the administration of lyophilized and depot products. Through proprietary formulation enhancements we can speed up the rehydration for difficult to dissolve molecules. Learn more about us at www.windgapmedical.com.
2017 Exhibitors
Battelle combines medical device design and development, formulation expertise and human centric design to create innovative drug delivery systems that condense the development timeline and get our clients' drugs to market faster. Battelle's cross-disciplinary teams of experts mitigate risk and cut a clear path to regulatory approval for pharmaceutical companies looking to gain a competitive edge. Visit us at www.battelle.org.
BAUMANN – a global leading spring and stamping manufacturer with dedicated medical approach (ISO13485). We are your competent and reliable development partner in drug delivery device projects. Visit us at www.baumann-group.com.
DigiM Solution LLC pioneers in microstructure science. DigiM provides X-Ray and Focused Ion Beam Scanning Electron microscopy imaging service, artificial intelligence based image analytics, and image-based flow rate prediction for the design, evaluation, and optimization of drug and its release performance, medical devices and their long term quality, and any material samples when microstructure is important. Visit www.digimsolution.com for more information.
At Haselmeier we work in close cooperation with our pharmaceutical partners to create and deliver the safest and easiest to use injection devices for their patients. Our proven device platforms, world leading engineering and global manufacturing capabilities combined with an intense focus on patient needs provides our partners with a total product solution that helps improve patients' lives. Visit us at http://haselmeier.com
Intertech Engineering specializes in disciplines centered on Medical Device design and development. Intertech supports clients through all phases of product development. Disciplines include Software Development, Hardware Development, Verification & Validation (incl. 820.70 & Part 11 Validations), Requirements Management, Risk Management and Software Regulatory Issues. Services offered include Assessments, Training, Consulting and Hands-on Engineering. Learn more at www.inea.com.
MANTA provides partners in the healthcare industry with award winning product development services. Our creative group specializes in early stage research / technology discovery to drive innovation and our ISO compliant process ensures product development excellence. Our team's interactive culture and multi-disciplinary expertise in human factors, design and engineering provides the basis of forward thinking that leads to groundbreaking concepts and competitive advantage. Learn more at www.mantadesign.com.
Maxon motor is a long-time partner of leading medical technology companies worldwide and provides system solutions by combining DC motors, gears and controllers into high precision intelligent drives. With over 50 years of experience, high-tech innovations and superior product quality, maxon is the reliable partner in drive technology. Individual, customized drive solutions is our greatest strength. For more information, visit www.maxonmotorusa.com.
Mikron Corporation Denver is part of the Swiss based company Mikron Automation. With 40 years experience, 590 employees and 3000 installations worldwide, Mikron Automation continuously innovates to supply the best automated assembly and testing solutions for devices such as pen/auto-injectors, inhalers, syringes, e-devices and diagnostic kits. Learn more about us at www.mikron.com.
NN, Inc Precision Engineered Products Group is an engineered solutions company, focusing on medical and drug delivery devices. We provide components, complex assemblies and clean room packaging, specializing in metal stamping, injection molding and ISO Class VIII clean room assembly. Learn more at www.pep-corp.com.
Pharmaero ApS is a 50:50 joint venture between Scandinavian Health Limited (SHL) and Xellia Pharmaceuticals ApS . Pharmaero was founded in 2009 and is headed by Tomas Norling. The ADI®, Pharmaero's key product, aims at optimizing treatment and addressing patient adherence by limiting some of the barriers in inhalation therapy. For more information, please visit www.pharmaero.com.
Polysciences, Inc provides custom manufacturing and development of biodegradable materials for drug discovery & delivery, medical devices, biotechnology, electronics and analytical chemistry industries, as well as high purity optical monomers, UV absorbing materials and specialty polymer additives to the ocular lens industry. To learn more, please visit www.polysciences.com or call (215) 343-6484 about your next project.
Renishaw is applying precision engineering technology to the challenges of medical research, diagnostics and surgical procedures. Our aim is to help leading clinicians to enhance the safety and cost-effectiveness of their procedures, improving patient outcomes through accurate delivery and development of implantable devices.
Our healthcare product portfolio includes medical devices, planning software and surgical robotic systems for use in procedures such as deep brain stimulation (DBS) for Parkinson's disease, and Stereoelectroencephalography (SEEG) for the treatment of epilepsy. We also manufacture patient specific implants (PSI) for craniomaxillofacial (CMF) surgery, often required as a result of trauma or oncology therapy. Visit us at www.renishaw.com/en.
Our core competencies consist of design, development and production of customized electric motors, in large quantities. We are committed to develop mechatronic drive systems solutions that operate in challenging environments. Since 1936, our focus on innovation, best in class quality and service is our key to success for worldwide OEM. Sonceboz is ISO 13485 certified. www.sonceboz.com
SES provides value to our clients involved in producing innovative drug delivery systems. We use our extensive background in failure analysis, predictive methodology, risk assessment, and sustaining engineering to complete end-to-end development solutions for a wide range of drug delivery technologies. We support our clients solving their biggest development challenges. innovation.stress.com
Team Consulting is a multi-award winning medical device product development consultancy based in Cambridge, UK. Our specialists in human factors, engineering and industrial design work closely with our clients to develop complex drug delivery and medtech devices from concept to launch. Learn more at www.team-consulting.com
teamtechnik is an international market leader in innovative production technology, offering high-quality production systems and process technology for assembly and functional testing, high-performance and precision products in the automotive, medtech and solar sector. Learn more at www.teamtechnik.com
We develop alliances with pharmaceutical companies on a global scale, using Terumo technology to develop, manufacture and supply carefully crafted solutions to their injectable drug delivery challenges. We pride ourselves on offering a full portfolio of products and services for the pharmaceutical industry, backed by unrivaled scientific expertise and know-how. By anticipating new trends and maintaining a constant dialogue, we provide a first class customer experience. Learn more at www.terumo-ps.com.
URSATEC stands for innovative developments in preservative-free pharmaceutical, medical device and cosmetic products such as oral and nasal sprays. Safe protection against contamination by microorganisms, even after the opening of a package, is guaranteed by the dual microbiological protection of the patented dosing systems 3K® and COMFORT®. Learn more about us at www.ursatec.com/en.
2017 Soapbox Sponsors
BioHealthWays is a biopharmaceutical company developing specialty drug delivery technology to sustain the release of biologics. We are focused on fighting preventable blindness. To learn more, visit www.biohealthway.com.
Pendant Biosciences is an advanced materials company developing innovative surface coating and drug delivery technologies using a unique, polymer-based platform. The company is initially focused on applications within the orthopedic market, and its lead product candidate is a surface modification intended to reduce the risk of infection associated with certain orthopedic implants. The platform also serves as a product engine with broad utility in multiple therapeutic areas.
Sonoran Biosciences is an early stage pharmaceutical company that has developed SB Gel, a viscous and resorb-able carrier that provides multi-day sustained drug release. Sonoran's first product, SBG002, is being developed to enable one-stage treatment of prosthetic joint infection. Sonoran is currently funded by an NIH Phase 2 SBIR grant. Learn more at www.sonoranbiosciences.com.
Subcuject is a start up company focused on providing a flexible, reliable, environmentally friendly, wearable injection device for the fast growing market of biologics at a significantly lower cost than other devices. The device utilizes next generation osmotic technology.


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What is 3D printing?
3D printing starts with a virtual image or a 3D CAD file of an object. The 3D printer creates the product by laying down thin successive layers of material until the object is created.
3D printing can be used for rapid prototyping and reverse engineering. The process can save time and money when developing new products by creating a prototype of a new design without the need of moulds, patterns or fabrication. Modifications and design changes can be done quickly and another 3D print created for final design approval. In many cases the 3D printed part can be tried and tested in the field before tooling has commenced. By making changes at this pre-production stage will save in the long run.
A virtual 3D model or CAD model is required to be able to 3D print. Rocwood Designs can assist you with the design and 3D print, or just the CAD model if you prefer to use your own printer.
A virtual model can also be created by 3D scanning an existing object, and then printing a replica of the scanned object


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Forest History Today Magazine
Fall 2012
View the table of contents for the Fall 2012 issue below. (view cover image)
Feature articles include discovery of the emerald ash borer in the U.S.; the search for Aldo Leopold's "green fire" site; why the findings of the forest surveys of the 1890s still matter; and the origins of the U.S. Forest Service slogan "Caring for the Land and Serving People." The History on the Road and Biographical Portrait columns both focus on the Crossett Experimental Forest.
Linked articles are accessible in PDF format (requires Acrobat Reader).


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This property has been removed by the agent. It may be let or temporarily removed from the market
1 bedroom apartment to rentVictory Parade, The Royal Arsenal, SE18 6FT
Fixed Price £1,195 pcm| £276 pw fees apply
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Brand new 1 bedroom apartment on the 5th floor of the sought after Compton House. Open plan Lounge/ kitchen area, bedroom with mirrired fitted wardrobes, storage cupboard and fully tiled bathroom. Within walking distance to DLR, Thames Clipper and main line station. Other benefits include 24 hour concierge and Gymnasium, resturant/bars, Tescos express and Cafe.
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text:
Gaming the system
By Slow Dad - April 22, 2017
Ever wondered why people do what they do? Imagine being able to monitor and test how people respond to financial incentives. I did just that!One of the most fascinating projects I've worked on was a very "big brother" style behavioural monitoring system for a large retail bank.
The project sponsor had figured out that while most staff generally try to do a good job, they'll try much harder at the tasks for which they perceive they have been incentivised.
The sponsor hypothesised that if the incentivisation was aligned to the bank's strategic goals, then in the staff would do more of the things that would help achieve those goals and hopefully do them better.
Like all great plans it sounded simple and plausible.
Everybody has a plan until they get punched in the faceUnlike many executives I have met in my time, the sponsor didn't just like believing he was
|George Clooney and Julia Roberts in Ocean's Eleven.
A quick review of the current remuneration and incentives on offer was performed.
The staff were all permanent employees, earning above average but far from amazing wages. This meant they got paid just to turn up. In fact with paid annual leave, sick leave, maternity leave, bereavement leave, study leave, and the like they pretty much got paid regardless of whether they turned up!
If a staff member managed to sell a credit card product they received $25.
If a staff member managed to sell an owner occupier mortgage they received $125.
The thing was a credit card is a "do you want fries with that?" convenience product. It takes almost no time for a staff member to complete the required paperwork whenever some gormless lackwit inevitably said yes to the opportunity to take on even more unsecured personal debt without sparing any thought about how they would pay it back.
A credit card earned the bank an annual fee of $25, plus around 28% interest on outstanding balances.
A mortgage on the other hand was a never-ending paperwork nightmare for staff to endure. Background checks, identify checks, credit checks, valuation checks and so on. The conveyancing process must be successfully traversed in order for the mortgage to be drawn down, and the staff didn't receive their $125 incentive until the punter had jumped all of those hurdles.
A mortgage earned the bank an establishment fee of around $600, plus around 6% interest on the outstanding balance.
Unsurprisingly branch staff didn't invest much of their time trying to sell mortgages. In fact the opposite was true. Staff actively discouraged any random drop-ins enquiring about mortgage products, simply because of their sheer horror at the prospect of running that compliance driven paperwork gauntlet.
Keeping your eye on the prizeThe sponsor and I asked ourselves what we would do in the branch staff's situation. The sponsor said he would sell as many credit cards as possible.
I called bullshit on this. The incentive was so low that it wasn't worth chasing. If a customer asked about a credit card I'd sell it to them, but I wouldn't put myself out trawling for business.
Then the sponsor nodded and begrudgingly agreed with me. $25 was chump change to him, it would not make a material difference to his pay packet. It wouldn't pay for his groceries for a week, or even a full tank of petrol in his car.
The question was how much incentive was enough?
How much is enough?To answer this I needed more information.
- I needed to understand how much each individual product was actually worth to the bank, as sustainable maximum incentive levels had to be below this amount.
- I also needed to understand the volume of organic product inquiries for each type of product. This would provide a baseline against which the effectiveness of any incentivisation scheme could be measured.
- Next I wanted to know what the conversion rates actually were. What percentage of product inquiries were successfully converted into sold products.
- Finally I needed to know the amount of time and effort required to actually sell each type of product.
Human guinea pigs for fun and profitOver the next six weeks various incentivisation mixes were developed and applied. Results and the ensuring staff behaviours were carefully monitored in an attempt to identify the optimal combination of carrot and stick required to achieve the bank's strategic goals.
So far, so good.
However once I started evaluating the results I noticed something interesting about human nature.
People are largely driven by self-interest.
They are also for the most part lazy and impatient.
These factors combined meant employees seized on the immediate rewards offered by the easy to sell commodity products such as credit cards. However they still shied away from those products requiring more work, like mortgages and insurance products.
Nothing earth shattering there.
Selfishness and self interest win outThen I noticed that some of the behaviours I was observing didn't make economic sense. Staff were undertaking activities that would not result in the optimal financial outcome for themselves.
When I dug into this I discovered that the staff had interpreted some of the incentive mixes differently to how I had intended them to be applied, and were attempting to game the system.
On the one hand I was relieved that I could now understand their behaviours, and self interest was still driving their prioritisation decisions about which activities they would pursue and which they would avoid.
This presented the project team with a challenge, as not only did I need to evolve an optimal incentivisation mix to elicit a desired set of behaviours, I also needed to factor in the branch staff attempting to game the systems I was developing. This resulted in my attempting to second guess the likely responses of the staff, creating an elaborate game of cat and mouse that was in equal parts frustrating and fascinating.
Lessons learnedAt the conclusion of the evaluation period I prepared some recommendations for the sponsor (who had been actively involving in pulling the incentivisation leavers throughout). They weren't what he wanted to hear initially, but once he sat down and thought about what I had to say he conceded not every problem can be solved through incentivisation alone.
The report concluded that the compliance paperwork burden of many specialist products was too great for it to be sufficiently incentivised in a bank branch. The staff just didn't have the time (nor the interest) required to do this job well.
Therefore I recommended all specialist products such as mortgages, insurance, and financial planning be referred to a dedicated team of professionals who specialised in just that one product. This proved to be controversial at first, but several years on all the other leading retail banks appear to have adopted a similar approach… because it works!
I suggested that the relative amounts of the incentives be driven by that product's anticipated profitability of that product. They should also be aligned with the bank's business planning and marketing activities. There was no point promoting one product while incentivising another, the conflict of interest for the branch staff was obvious.
There were a bunch more data driven recommendations, but those were the relevant ones for today's post.
So what?What does this have to do with personal finance?
Much like the bank branch staff, we are all easily led and manipulated.
Firms constantly dangle carrots… loyalty programmes, frequent flyer miles, and the like.
It was recently tax season, and there were a ridiculous number of posts in the blogosphere talking up the paying of (often large) tax bills using reward earning credit cards. However hardly any of those posts actually ran the numbers to compare the relative costs of the 2-3% credit card surcharge versus the value of the reward points earned.
Using my own reward card (albeit a much less generous UK based one) each £1 spent earns a reward with a monetary value of £0.005. To pay a £10,000 tax bill using that card would therefore earn a £50 reward. Earning that reward would incur a surcharge of £300.
Doesn't seem like such an amazing deal to me.
What about an airline reward card?Paying that tax bill would earn 10,000 reward points... again at a cost of £300.
My reward points trip to Cuba earlier this year "cost" 45,000 reward points per return ticket.
Were that reward "earned" via surcharge incurring purchases such as tax bills it would require me to "spend" £45,000 plus a surcharge of £1,350 to pay for a ticket worth £550 (excluding the taxes which I had to pay in cash anyway).
That doesn't seem like such a good deal either.
These reward schemes are certainly not the most generous or the most smartly used, but they are certainly representative of a common problem confronting all of us.
The moral of the story?There is no such thing, despite what bloggers may tell you, as a free lunch. Trust, but verify, advice you receive... but always run the numbers to validate whether you're receiving sage advice or being sold some complete and utter bullshit.
Much like the mindless acceptance of the "4% safe withdrawal rate", unquestioning acceptance of the merits of "travel hacking" should also be challenged. There are definitely times when doing it can result in a win, but there are many others where the blind pursuit of loyalty points will result in a sub-optimal outcome.


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Canine Osteosarcoma
Canine osteosarcoma, fully funded trial evaluating a novel immunotherapy procedure. Either Sorrento Valley or San Marcos hospitals. A pre-amputation consult is required but a pre-consult histologic/cytologic diagnosis is not necessary.
--Please contact Dr. Brenda Phillips at 858-875-7500 or Dr. Andi Flory at 760-466-0600 for more information.
Lymphoma Trials
We are now enrolling eligible canine participants with peripheral lymph node lymphoma in a new study to evaluate the benefit of corticosteroids. To be eligible to participate in the trial, a lymphoma diagnosis has to be confirmed or must be highly suspected and chemotherapy treatment declined. Eligible dogs cannot have received any steroids before enrollment. The study provides FREE palliative prednisone.
--Please call Oncology Services at (858) 875-7500 or (760) 466-0600 with any questions.
Clinical Trial for Atopic Dogs
*NEW* Dr. Laura Stokking is enrolling canine patients in a new clinical trial for atopic dogs. Patients cannot have had any long-acting treatments for allergy, such as glucocorticoid injections or Cytopoint. Food allergy should have been ruled out prior to enrollment.
--Please contact Drs. Laura Stokking or Wendy Terry at (858) 875-7500 for additional information.
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Novel Rattlesnake Antivenom
*NEW* We are currently enrolling dogs that have been bitten (or suspected to have been bitten) by a rattlesnake for treatment with a novel antivenom. Enrolled dogs will receive free bloodwork on presentation (CBC, chemistry, coagulation panel) and trial antivenom at no cost to the client. Patients are required to return for a 24 hour post-antivenom administration recheck and free bloodwork (CBC, chemistry, coagulation panel). Owners must commit to the 24 hour recheck as well as use of their pet's photos and/or videos for research and publication purposes. Patients are now being enrolled at Sorrento Valley, and North County enrollment begins August 14.
--Contact Dr. Erica O'Donnell or Nicole Edwards, RVT at (858) 875-7500.
Internal Medicine
Canine Bile Acid Diarrhea and Microbial Dysbiosis Study
We are enrolling dogs with signs of inflammatory bowel disease, with or without histopathologic evidence, that are on current standard therapies (prednisone, diet) but continue to have diarrhea. A GI panel and fecal analysis for bile acid concertation and enteropathogens, along with a dysbiosis index will be performed through the GI Lab at Texas A&M. Dogs with a non-GI disease to explain their sign will be excluded. Patients will be randomly assigned into a placebo or cholestyramine group. Owners will be asked to grade their dog's feces daily. Dogs will be re-evaluated at 3, 6, and 16 weeks post induction of therapies. At these rechecks, a fecal sample will be collected and submitted for a fecal bile acid analysis and microbial evaluation. All study related expenses will be funded. Cost to initial diagnosis of a chronic enteropathy will be covered by clients.
--Contact Drs. John Gil or Steve Hill at (858) 875-7500
Clinical Trial for Diabetic Dogs
VSH is participating in an exciting new clinical trial using a novel stem cell therapy to resolve diabetes mellitus in dogs! Dogs must weigh 5 to 12 kg, and be free of significant other systemic illnesses, on insulin (preferably Vetsulin), and at least partially controlled. Owners must be willing to perform glucose curves at home (with training), and to reliably bring the dog in for follow-up visits over 3 years. All study-associated costs are covered for the study duration (labs, procedures, insulin, glucometer, exams, etc.), including the initial screening visit, so we encourage any potential candidates to come in for formal screening with Drs. Loy Son, Gil, Dong, or Fischer.
--Visit website for additional details or call (858) 875-7500.
Feline IBD/GI Small Cell Lymphoma Study and Proteomics Study
We are enrolling cats with chronic gastrointestinal disease that are suspected of having either inflammatory bowel disease (IBD) or gastrointestinal small cell lymphoma (GI SC LSA). Endoscopy will be performed and GI biopsies will be obtained for histopathology, immunohistochemistry (IHC) and PCR for antigen receptor rearrangements (PARR). A 3 week follow-up will be required. Blood, urine, and fecal samples will be collected for proteomic analysis at the time of endoscopy and follow-up visit. The cost of the histopathology, IHC and PARR is funded. GI panel is also funded by the proteomic study.
--Contact Drs. Betty Chow, Steve Hill or Keith Richter at (858) 875-7500
Glucocorticoids and spec cPL study
Patients who will be started on glucocorticoids (minimum dose of 0.5mg/kg/day) and will need to be on them for at least 3 weeks. Patients will receive a spec cPL prior to administration of any glucocorticoids and at least 3 weeks after starting glucocorticoid therapy at no charge. Patients are being enrolled in North County and Sorrento Valley.
--Please call Drs. Sarah Cocker or Keith Richter at (858) 875-7500.
Tarsal Replacement Surgery
*NEW* Clinical trial on tarsal replacement surgery. Dogs greater than 30kg with end stage osteoarthritis of the Tarsus.
--Contact Dr. Josh Jackson at (858) 875-7500 for details.


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Happy Birthday GabrielOct. 15th, 2012 09:54 pm
Gab is already one year old! Hard to believe. I feel a bit bad 'cause I haven't really done much with him yet. ^^;; Just been a busy year.
There will be a photostory for Uriel soon. I just haven't had the time. And its going to be crazy with these two having b-days so close together. At least they do interact a lot. So may just do joint b-day stories in the future. lol


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- More
1859-S $1 MS63 PCGS....Click the image to load the highest resolution version.
Tied for Finest PCGS 1859-S Dollar, MS631859-S $1 MS63 PCGS. Medium gold toning covers the obverse and lighter champagne toning crosses the reverse of this fully lustrous piece. The underlying surfaces exhibit a trace of reflectivity in the fields with satiny luster on the devices, resulting in a mild cameo appearance.
Just 20,000 silver dollars were coined in San Francisco during the year, the first of the Seated silver dollar denomination to be coined at that facility. During the few previous years of production, the young mint was concentrating on gold coins, and also producing limited quantities of fractional silver to answer the need for change in the gold region. The next meaningful production of silver dollars in San Francisco would have to weight until 1872, when another 9,000 pieces were coined. Of course, a small number of 1870-S dollars were minted with about a dozen known, and a few hundred 1873-S Seated dollars were also coined, but remain unknown today. Population: 7 in 63, 0 finer (4/08).(Registry values: N7079) (NGC ID# 24YZ, PCGS# 6948)
Weight: 26.73 grams
Metal: 90% Silver, 10% Copper
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