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Public Health
Academic Year: 2009 – 2010
The goal of the Public Health Department is to prepare graduates as competent public health practitioners. Public health is an essential function of modern society. It is, in the words of the Institute of Medicine, "What we as a society do collectively to assure the conditions in which people can be healthy." Assuring the public's health at the community level often means affecting policies and actions at the national, or even international, level. Public health professionals must deal with myriad issues: access to quality health care; prevention and control of disease; environmental protection; the health needs of special populations; data analysis and evaluation; policy planning and administration; and health promotion.
The department offers two options for graduate-level study in public health: a generalist MPH degree with a strong interdisciplinary foundation for practice in public health, and an MPH with a concentration in Environmental Health within which a student may generalize or may choose to emphasize preparation in risk assessment and emergency preparedness. The curriculum enables students to understand 1) the various factors that affect the health of a community, 2) the methods to identify and measure community health, and 3) the components that comprise public health services delivery systems (cost, planning, and administration). While the department's required core courses provide the generalist background needed by all students, the concentration core in environmental health and elective courses allow students to concentrate on a particular aspect of public health. The MPH with a concentration in Environmental Health is an accredited curriculum through the National Environmental Health Science and Protection Accreditation Council (EHAC). The MPH with a concentration in Environmental Health may be completed on campus or may be taken entirely online.
Entrance Requirements
Applicants must submit an admission application and transcripts from previous college-level academic work to the UIS Office of Admissions. As a second part of the admissions process, applicants must submit to the department the following: 1) an essay outlining professional goals and identifying past academic work and/or employment related to these goals; 2) three completed recommendation forms from employers, professional peers, or educators; and 3) Graduate Record Exam (GRE) scores in the general examination. Other aptitude tests — Medical College Admission Test (MCAT), Dental Aptitude Test (DAT), Law School Admission Test (LSAT), or the Graduate Management Admission Test (GMAT) — can be submitted. Applicants with post-baccalaureate degrees are exempt from submitting GRE scores.
Applicants must have earned an overall GPA of 3.00 (4.00 point scale) for previous academic work, completed a 300-level or higher biostatistics or statistics course within the last three years and received a B or better grade, and completed a minimum of 30 semester hours in the natural sciences at the baccalaureate level or higher. Conditional admission is possible for those with public health or environmental health experience who are missing one or more of the conditions listed. To be fully admitted, conditionally admitted students must have a 3.00 GPA at the end of their first 12 semester hours of study and receive a B or better grade in MPH 503 Biostatistics for the Health Professional. Students who take TOEFL exams must score at least the graduate level established by the UIS Office of Admissions.
Advising in the Public Health Department provides an individual approach to the academic and professional development of each student. On admission, each student is assigned a temporary advisor to assist with academic planning. Thereafter, students may choose an advisor from department or associated faculty. Students prepare an educational plan before registering for courses in order to map out progress through the degree consistent with career and personal goals.
Students must maintain a B- or better average during their course of study. A maximum of eight hours of C grades is applicable to the degree, provided they are balanced by an equal number of A grade hours and an approved Student Petition is on file in the Office of Records and Registration. Courses taken on a CR/NC basis will not count toward the degree.
Major Requirements
The MPH degree requires that students complete 48 semester hours of course work, 24 hours of which are required core courses, including a four-hour internship. The student must declare either a generalist course of study or a specialization in environmental health and take 24 hours of concentration core or electives.
Required Core Courses (24 Hrs.)
MPH 506 Community Health Research 4 Hrs.
MPH 511 Foundations of Epidemiology 4 Hrs.
MPH 521 Environmental and Occupational Health 4 Hrs.
MPH 531 Public Health Policy and Administration 4 Hrs.
MPH 561 Community Health Education 4 Hrs.
MPH 581 Internship
or PAD 561 Graduate Public Service Internship Seminar
in Organization Environment in the Public Service 1 Hr.
Generalist MPH (total 48 hours)
Required core above (24 hours)
and at least one course from each of the following categories (20 hours) or may petition to specialize in one of the following certificate options : epidemiology, community health, or environmental health.
Risk Assessment
MPH 449 Environmental Toxicology 4 Hrs.
MPH 526 Risk Management and Communication 4 Hrs.
MPH 527 Environmental Risk Assessment 4 Hrs.
MPH 528 Risk Assessment: Air, Land, and Water 4 Hrs.
MPH 529 Risk Assessment Practicum 4 Hrs.
Advanced Epidemiology
MPH 512 Epidemiology of Infectious & Chronic Diseases 4 Hrs.
MPH 514 Analytical Epidemiology 4 Hrs.
Research Tools
MPH 508 Program Evaluation for Health Professionals 4 Hrs.
MPH 522 Analytical Tools for the Environmental Sciences 4 Hrs.
MPH 575 Economics for Policy Analysis 4 Hrs.
ENS 404 Fundamentals of Geographic Information Systems 4 Hrs.
ENS 503 Advanced GIS Applications in Environmental Planning 4 Hrs.
Policy, Administration, and Management
MPH 408 ECCE: Addiction 4 Hrs.
MPH 419 Environmental Law 4 Hrs.
MPH 428 Laboratory Science in Public Health 2 Hrs.
MPH 438 ECCE: Monsters, Medicine, & Myths 4 Hrs.
MPH 450 ECCE: Chemicals and the Citizen 4 Hrs.
MPH 471 ECCE: Emerging Diseases 3 or 4 Hrs.
MPH 484 Policy of Ambient and Indoor Air Quality 4 Hrs.
MPH 486 Solid and Hazardous Waste Policy 4 Hrs.
MPH 535 Public Health in the Political Arena 4 Hrs.
MPH 536 Contemporary Issues in Public Health 2 or 4 Hrs.
ENS 485 Environmental Policies: Water Quality 4 Hrs.
Additional elective (4 hours) taken inside or outside concentration
MPH with concentration in Environmental Health (total 48 hours)
Required core above (24 hours)
Required Environmental Health concentration core (8 hours)
MPH 449 Environmental Toxicology 3 or 4 Hrs.
MPH 527 Environmental Risk Assessment 4 Hrs.
EH concentration electives
Students may generalize by sampling from several categories listed below (12 hours) or may petition to specialize in one of the following certificate options: Risk Assessment or Emergency Preparedness and Homeland Security
Risk Assessment
MPH 526 Risk Management and Communication 4 Hrs.
MPH 528 Risk Assessment: Air, Land, and Water 4 Hrs.
MPH 529 Risk Assessment Practicum 4 Hrs.
Research Tools
MPH 508 Program Evaluation for Health Professionals 4 Hrs.
MPH 514 Analytical Epidemiology 4 Hrs.
MPH 522 Analytical Tools for Environmental Sciences 4 Hrs.
MPH 575 Economics for Policy Analysis 4 Hrs.
ENS 404 Fundamentals of Geographic Information Systems 4 Hrs.
ENS 503 Advanced GIS Applications in Environmental Planning 4 Hrs.
Policy, Administration, and Management
MPH 419 Environmental Law 4 Hrs.
MPH 428 Laboratory Science in Public Health 2 Hrs.
MPH 471 ECCE: Emerging Diseases 3 or 4 Hrs.
MPH 478 ECCE: Crisis in Environmental Health 4 Hrs.
MPH 484 Policy of Ambient and Indoor Air Quality 4 Hrs.
MPH 486 Solid and Hazardous Wastes Policy 4 Hrs.
MPH 536 Contemporary Issues in Public Health 2 or 4 Hrs.
ENS 485 Environmental Policies: Water Quality 4 Hrs.
Additional elective (4 hours) taken inside or outside concentration
Closure Exercise
The closure experience is a comprehensive written examination based on a case study with questions designed to test students' ability to integrate the knowledge and skills that they have gained from the core curriculum. A student must complete all core courses prior to taking the comprehensive exam, but may take the exam concurrently with electives during the last semester of study. The student must successfully complete the exam within one year after completing course work for the degree. Students who do not complete the examination during their final semester of study must enroll in MPH 583 (zero credit hours, one billable hour) until they pass the exam. Details about the procedure are provided in the MPH Student Handbook.
All students in the MPH curriculum must take 4 hours of internship (MPH 581) under the guidance of their academic advisor. Details about the internship are provided in the MPH Student Handbook. Students may petition to substitute 4 hours of Graduate Public Service Internship (PAD 561) for MPH 581.
The MPH professional option provides an opportunity for physicians and others with earned doctorates and at least one year of health-related experience to earn an MPH degree at UIS. The option requires completion of the 24 hours of core courses including the internship and 12 hours of general electives (36 hours total). Other applicants may be eligible for admission to this option and will be considered by the admissions committee on a case-by-case basis. Included are 1) those currently enrolled in a physician residency-training program, 2) those who are in the process of completing a doctoral-level health-related degree and who have at least one year of health-related experience, and 3) those who have an earned master's degree in a health field and who have at least three years of health-related experience. Interested applicants should contact the Public Health Department for information about the application process.
UIS' Departments of Public Health and Public Administration have an articulation agreement that allows interested students to obtain a master's degree with a joint degree (MPA/MPH) in Public Health and Public Administration. The MPA/MPH joint degree may be completed on campus or may be taken entirely online. Contact either department for details.
The Public Health Department offers five graduate certificates for specialized study in public health. These certificates, some of which are available online, may be taken by either degree or non-degree seeking students interested in advanced preparation in:
* Community Health
* Emergency Preparedness and Homeland Security
* Environmental Health
* Epidemiology
* Risk Assessment
Please see the Graduate Certificates section of this Guide for additional information.
Master of Public Health
Kathy DeBarr, Mark Edgar, Shahram Heshmat, Sharron LaFollette, James Veselenak
Emeritus Faculty: Remi Imeokparia, Michael Quam
Associated Emeritus Faculty: William Martz
Adjunct Faculty: Jennifer Davis. Greg Michaud, Ken Runkel
Online Coordinator: Lenore Killam
Phone: 217/206-6250
Email: email@example.com
Website: www.uis.edu/publichealth/


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patdabunny wrote:discspeed wrote:177 2FR Buzzz...almost a FWY driver
This is what I've been thinking.
I've been using my buzzzes and comets for everything 400' and under (with some obvious exceptions where a driver is called for) lately and have had really good success. For one, they don't fade nearly as hard and don't skip as far as true drivers. I'm really surprised that more people don't use Rocs/Buzzzes/Comets/Etc for this length vs something like a TB. I know the obvious answer of people not having the power but I think many more people do but have been seduced by the "latest and greatest" from the manufacturers telling them they "need" a driver.
I stop considering a mid outside of about 360' on flat ground, but sometimes I'll use a PD on a 320' shot because I have to hit a tight gap off the tee and I want to throw very effortlessly and accurately.

subset: commoncrawl


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SHEFFIELD TOWNSHIP -- This year's early voting turnout has squashed a previous record set in 2008.
The county has already had more than 50,000 voters cast their ballots early at the Lorain County Board of Elections office or by mail.
The office is open from 8:30 a.m. to 2 p.m. today and anybody still in line at closing will be allowed to vote.
In 2008, roughly 48,200 people voted early -- 14,367 in person and 33,833 by mail.
As of calculations made Saturday, 16,924 people had voted in person and 34,670 by mail. An additional 800 people estimated to have voted in person yesterday.
"These are record numbers for Lorain County," Adams said. "2008 had been our record before."
At 5 p.m. when the office was scheduled to close yesterday, roughly 80 people still stretched out the door, waiting to vote, said Paul Adams, director of the Lorain County Board of Elections office.
"For only being open for four hours, that is about 200 people we were processing an hour," Adams said.
More than 1,000 people also voted on Saturday.
In August, Ohio's Secretary of State Jon Husted set uniform hours for all of the county's board of elections and barred voting in the three days preceeding election day. The Supreme Court overturned the move in October.
"I think it is obviously popular in our county and that it has been helpful to the voters in Lorain County," Adams said.
In the past, Lorain County only allowed early voting up to the Saturday before the election.�
"This is the first time the board of elections in Lorain County has ever been open Sunday," he said.
The extended voting is likely to cause an extra $6,000 in costs to the local board of elections because of increased staffing, Adams said in a previous story.
In 2008, more than 100,000 people in Ohio voted early during the three days leading up to the election.
Mail-in ballots must be postmarked by today to be counted for the election.
Registered voters should visit www.MyOhioVote.com for information about polling places for Tuesday.


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It is hard to recall a time in the last 40 years when San Diego City Hall was this broken.
In a remarkable display of stalemate, if not dysfunction, Mayor Bob Filner stood before the City Council Tuesday and threatened an unending legal battle with the council over how the newly created Tourism Marketing District should operate and how its promotional dollars – some $30 million a year – are spent.
He accused virtually every council member, as well as City Attorney Jan Goldsmith, of violating political ethics laws. He said it was "irresponsible" of Council President Todd Gloria to have placed the issue on Tuesday's agenda. He accused the tourism officials of "arrogance" and he said the "pony show" of industry officials, workers and others testifying on the matter at the council hearing amounted to "an attack on me rather than an attempt to reach a solution." And he repeated his criticisms of the $435,000 salary paid to Joe Terzi, CEO of the Tourism Authority.
Moments later, the council voted 6-1 to require the mayor to sign something the council knows he won't sign – the operating agreement for the marketing district. That will set up a mayoral veto, a likely council effort to override the veto, and then, the mayor promised, more legal action. Filner vs. City Council could go on for years.
All of this arose as negotiations between the mayor and tourism officials to resolve their differences over the TMD broke down. One tourism official was quoted earlier in the day saying the talks were "positive, and we're getting closer to a final compromise." The mayor himself said at the council hearing that the negotiations were "that close."
But "close" does not constitute agreement, and the possibility of agreement now seems remote, if not impossible.
At the core of this dispute is the mayor's contention that the 2 percent fee added to hotel guests' daily bill is illegal because it was approved only by a vote of local hoteliers and not by San Diego voters in an election. Proposition 26, approved by voters in 2010, requires a two-thirds public vote to approve new taxes. The legality of the local fee has already been challenged in court, but there has not yet been a substantive ruling.
The question now is whether anything can be done to salvage a resolution.
If not, the question then becomes the degree to which the relationship between the mayor, council and attorney have become so poisoned that other City Hall issues are impacted as well. It is hard to imagine that Gloria, most of his colleagues on the council and Goldsmith will simply let bygones be bygones. This was, after all, not the first flaring of tempers.
"It is a sad day for San Diego that we have come to this," Filner told the council.


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Forklift Rental In Georgetown, Delaware
Moving any item from one place to another can be laborious and time consuming , especially if the item is heavy. Earlier manual laborers had to be hired for relocating items , however today a Forklift Rental can accomplish the same task faster at a far cheaper rate. A Forklift is a vehicle which is specifically designed for moving items from one place to another, lifting the item with a fork like design and depositing it at another place as desired. Since many organizations and individuals may require a forklift only for a limited time like a few hours or few days, it advisable to consider a forklift Rental, wherein the firm or individual hires the forklift which meets their requirement from Forklift Rental Georgetown, Delaware after paying the specified fee.
Like most equipment, purchasing a forklift can be expensive, especially for a firm who is not planning to use the forklift regularly. For example an office or home may require a forklift if some renovation is taking place and they have to move the different items in the office or home to another place as part of the redesign. There are many benefits of renting a forklift from a well established Forklift Rental Georgetown, Delaware.
- Low cost of hiring the forklift compared to outright purchase
- Can choose from a wide variety of forklifts for rent, depending on the requirement, for some applications a large forklift may be required, and in other cases, a smaller and inexpensive forklift may be sufficient
- Maintenance of the forklift taken care of by the forklift rental company
- Safer than manually moving items as there is a possibility of injury
- Inexpensive and faster compared to other methods of moving items like manually moving items using hired labor
For example, the organization hiring a forklift can select a larger and more expensive forklift for moving the heavy equipment for a few days, and use a cheaper low capacity forklift for the rest of the period. This kind of flexibility is not available if the organization has purchased a forklif


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Crystal Palace look set to unveil former Cardiff City boss Malky MacKay as their new manager.
Mackay, Tim Sherwood and Martin Jol were the prime candidates following the departure of Tony Pulis last week, two days before the Premier League kicked off.
Palace appear to have chosen former Scottish international MacKay, who was willing to work with the current backroom staff at Selhurst Park, while Sherwood and Jol wanted to bring in their own people.
The Scot's close links with Palace sporting director and former Bluebirds head of recruitment Iain Moody, was also key.
Mackay's managerial career is relatively short, having taken his bow at Watford in 2009 following the resignation of Brendan Rogers.
However, it was with Cardiff City, whom the 42 year-old guided to the Premier League in 2013, where MacKay rose to prominence.


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Dozier comes off bench, hits homer in ninth
DETROIT -- Twins manager Ron Gardenhire said before Saturday's 12-9 loss to the Tigers that he'd prefer to avoid using Brian Dozier as he continues to recover from a tight lower back he aggravated during the series in Toronto.
With injuries to two third basemen on Saturday, the luxury of resting Dozier another full day wasn't afforded to Gardenhire. And while the injury might have prevented Dozier from being successful on the basepaths, he didn't have to find out. In his lone at-bat after entering during the eighth inning, Dozier homered to left field in the ninth.
The two-run blast cut Detroit's lead, once 11-1, to just three runs, but Eric Fryer struck out to end the game in the next at-bat.
"He made that look easy," Gardenhire said. "But I'm still worried about him.
"He took a swing, but he still was stiff toward the end of the game. He still hasn't had to dive. He hasn't had to run or slide."
Starting third baseman Trevor Plouffe exited the game in the fourth with what the team called a strained left oblique after he attempted a diving stop. His replacement, Eduardo Nunez, pulled his right hamstring legging out an infield single in the eighth inning, prompting Dozier's emergency appearance.
Gardenhire said the decision came down to Dozier or Kurt Suzuki, the team's usual starting catcher, but he opted for Dozier.
Matt Slovin is an associate reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.


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BP Comment Quick Links
|Strength of Schedule Report
December 1, 2008
GM for a Day
In the run-up to the Winter Meetings, which begin a week from today in Las Vegas, I'm going to resurrect a feature I've done sporadically in the past, "GM For a Day." It is exactly what it sounds like: I take over a team and do what I think needs to be done. (Note that no one has ever hired me based on these pieces.) With 30 teams and probably five columns before next Monday, I won't get to everyone, and I haven't picked the next four, so if you have a preference, send it in via e-mail and I'll use that feedback to select the next candidates.
Today, I slip into Ned Colletti's shoes and take over the Dodgers. Coming off of a division title as a high-revenue franchise with a fantastic farm system-even after sloughing off talent right and left over the last few years-you would think the Dodgers might be in fantastic shape. They're certainly better off than many teams, but look past the crown and the money and the kids, and you find a team that is going to be changed significantly a year from now, one that has a staggering amount of dead money on the payroll, and one which is run, from the top down, a bit strangely.
The core talent here is as good as you'll find for ability, age, payroll, and team control. Russell Martin, James Loney, Matt Kemp, Andre Ethier, Chad Billingsley, and Clayton Kershaw match up with any top six roster spots in the game once payroll and control are considered. Some teams go decades without having that much talent come through their system; the Dodgers will put five of those guys on the field 40 percent of the time next year. Throw in Hiroki Kuroda, James McDonald, Jonathan Broxton, Hong-Chih Kuo, and, perhaps, Chin-Lung Hu, and the Dodgers will have nearly half of their roster comprised of talent they developed or signed, with only Ethier a marginal call in that area. The Brewers, the Rays, and maybe the Diamondbacks are the only teams that can put that much internally-developed talent on the field in 2009.
Yet the Dodgers have some problems. Outside of Martin, and the notion that Matt Kemp is a center fielder, it's a pretty weak team up the middle. A Hu/Blake DeWitt middle infield is problematic, because as good as Hu is defensively, he's yet to show that he can hit above Double-A. He's a career .307/.331/.451 batter in the PCL, with home games in Las Vegas and just 13 walks in more than 350 PA, and a .193/.250/.250 hitter in parts of two seasons in the majors. Hu slugged .507 at two levels combined in '07, but that '08 performance is worrisome. His glove warrants their opening the season with him at shortstop, because bringing along Billingsley, Kershaw, and McDonald will be easier with the plus-plus glove at shortstop.
DeWitt was, in a small sample, a statistical positive at second base, and there's an argument that it's the only place his bat will play. On the other hand, he looked awkward at the keystone almost all of the time, the Dodgers currently have no third baseman, and second basemen are something of a dime a dozen. It seems like a better idea to move DeWitt back to third and hope that the upward trend in his plate discipline was more than just a lineup-position thing. It's an open question for the 23-year-old, who drew a disproportionate number of intentionals (nine of his 45) and had just three unintentional walks in 108 PA outside of the seventh and eighth slots in the lineup. With Andy LaRoche gone, however, DeWitt is the choice to play third.
That leaves second base as a hole. I'm not ready to anoint Ivan DeJesus as a middle-infield answer based on three great months at Double-A. His presence, however, makes me feel better about thinking of second base as a short-term problem, something DeJesus can solve very late next year or in 2010. With that in mind, I want to find a stopgap solution, something there are always plenty of at second base. With Loney and Hu at first base and shortstop, sacrificing some defense for offense is an option here, especially with the team lacking a true leadoff hitter. Ray Durham still provides OBP and won't require draft-pick compensation for signing him. A two-year, $8 million offer should bring him into the fold, and allow the Dodgers time to figure out what DeJesus and Hu will be for them.
I mentioned Kemp as a center fielder earlier... he's a right fielder by trade, with good raw speed that doesn't translate well to center, and equipped with a right-fielder's arm. The decision to play him in center, flanked by Ethier and Manny Ramirez, was absolutely correct late last year, but now, with Ramirez gone, ideally the Dodgers would find a center fielder, slide Kemp to right and Ethier to left, and give themselves a plus defensive outfield.
Well, "find" may not be the best verb. The Dodgers "found" Juan Pierre two offseasons ago, and Andruw Jones last winter, to disastrous results. Both are still around, soaking up $27 million in payroll and providing brutal performance for the money. Neither was terribly happy by the end of last season, reduced to part-time or no-time roles, and it is likely that both expect to get much more playing time in '09. Jones, in particular, is a problem, because his skill set doesn't translate well to the bench. He's a low-average, high-power guy without good raw speed; if he's not a starter, he's just sitting there. Pierre, at the least, can bunt and run, though his horrible arm makes him a liability in center field, and he would have no business playing a corner on a team with Ethier and Kemp.
There is no easy answer here, in part because a year after being lousy with center fielders, the free-agent market is short of them. All of the options are aging, injury-prone, or not very good, and quite frankly, the Dodgers have too much of those things. The trade market is basically Aaron Rowand; the Giants aren't exactly giving him away, and his declining stock with four years left on an expensive deal is a bad idea, anyway. Rocco Baldelli is an interesting gamble, perhaps in a platoon with Pierre where Baldelli could earn more than a right-handed batter's share of playing time, but Baldelli has played 162 innings in center field since 2006, and his body simply may not let him do more than that. The upside is there, but the Dodgers need a center fielder, and should look elsewhere.
Getting creative, the idea of trying to pry Rickie Weeks from the Brewers has merit. With the Dodgers having openings in both center field and at second base, they could trade for Weeks, and move him to center-and yes, Keith Law and I will eventually arm-wrestle for the rights to this idea-with the backup plan of sticking him at second base if the move fails, using Durham and Weeks in a Wally Backman/Tim Teufel Memorial "Look ma, no hands" platoon. That's a trade with upside that addresses a positional need and a lineup gap, and includes a fallback even within it. The Dodgers have dealt good prospects, and have been absolutely been in deals for guys like Casey Blake and Mark Hendrickson and Danys Baez; this would actually be a good use of Logan White's progeny. You don't waste Andrew Lambo or Scott Elbert this way, but maybe DeJesus, or a Xavier Paul-plus-pitcher combination?
There's a notion that the Dodgers have a rotation problem, but I don't see it, not unless Chad Billingsley's leg injury is that much worse than expected. A rotation of Billingsley, Kuroda, Kershaw, McDonald, and Stults will seem risky, but could be above-average across the board. Kuo is around, and Elbert could arrive late in the year. Jason Schmidt is still in the organization as well. I suppose if there was ever an argument for a six-man rotation, it would be the team with this much young pitching and rehab cases needing to manage a lot of workloads in one year.
A better solution is to buy your way out of the problem. Just eyeballing the numbers at Cot's, the Dodgers have $54 million or so (I prorated signing bonuses where applicable) committed to Jones, Schmidt, Kuroda, and Pierre, and some high-value arbitration-eligibles in Broxton, Ethier, and Martin. Let's say that group, all first-time eligibles, comes in collectively at $15 million, which is probably high. That leaves the Dodgers at $69 million in commitments for seven roster slots. Even with some bumps for Kemp and Loney-bumps that aren't mandatory-the Dodgers would still be well under their 2008 Opening Day payroll of $118 million.
I've argued again and again that the safest bet in this year's pitching market is Derek Lowe. The Dodgers have an established relationship with Lowe; he's been successful with them, and he does seem like the kind of pitcher better suited for the NL than the AL. They have more than enough payroll flexibility to offer him a premium over what Ryan Dempster-a pitcher who doesn't have anything like Lowe's track record-received, and because Lowe is a durable ground-ball pitcher in good condition, the risk they're taking is less than what any other team will be taking in signing Dempster, CC Sabathia, A.J. Burnett, or any other "name" free-agent starter this winter. Lowe would stabilize the rotation, increase the benefit of playing Hu at shortstop, and by pushing everyone back a slot, he would create depth on the back end that could be used in season to make a trade or just manage the innings of all the young pitchers.
With the big moves out of the way, the focus also has to be on managing Russell Martin better than was done in '08. Joe Torre burnt out his starting catcher last year, and Martin was overused in '07 as well; he needs to be given a backup catcher worth playing. The Practically Perfect Backup Catcher, Gregg Zaun, is a free agent who fits nicely with Martin, a switch-hitter who provides OBP from the left side and who, honestly, isn't a great defensive player. With that said, Zaun may be at the point of his career where he's more risk than reward. No matter who the choice is-Dave Ross, or Javier Valentin, or Ivan Rodriguez-the Dodgers have to bring in a catcher that Torre will play every five days or so, or risk destroying a tremendous asset in Martin.
What about Manny Ramirez? Well, he's 36, and he's a big negative defensively whose presence creates worse defense at the other two outfield spots as well. There are better fits for Ramirez than the Dodgers, and the team should recognize that and put their money elsewhere. Letting Ramirez's fantastic two months drive a $50 million decision would be a mistake.
So here's the plan, in order of importance:
These things done, my 2009 Dodgers:
Weeks CF
Bench: Pierre, Valentin, Delwyn Young, Tony Abreu, Jason Repko
Rotation: Lowe, Billingsley, Kershaw, Kuroda, Kuo, Schmidt
Bullpen: Broxton, Saito, Cory Wade, McDonald, Stults, Elbert
Joe Sheehan is an author of Baseball Prospectus.
85 comments have been left for this article.
BP Comment Quick Links
HI Joe,
Dec 01, 2008 11:02 AM
Dr. Dave
Maybe it's just me, but it seems like the Dodgers' best bet with Jones might simply be to put him out there in CF every day and hope he returns to something vaguely resembling his past. They need a real CF, it's a sunk cost, and it's just as likely to be useful as any of the free agent options. Last year's performance is no more relevant than last year's salary. What does PECOTA expect from him, I wonder?
Dec 02, 2008 09:41 AM
Randy Brown
I think the Tigers would be an interesting subject for GM for a Day. You've got a veteran, flawed team with at least 3 holes to fill. You have limited flexibility due to a nearly barren farm system and you need to maintain or shed payroll. You've also got a lineup that should score a lot of runs and you can erect a fence post at shortstop that would prevent more runs than Renteria did in 2008.
Dec 01, 2008 11:07 AM
Alright, Joe, that one wasn't too hard. Give yourself a real challenge and do the Giants next!
Dec 01, 2008 11:15 AM
John from Bel Air
That would be too easy. Don't sign anybody, do nothing to change the roster. Try to trade Rowand, Zito, Winn, Roberts, and Molina for some value. Plan to write off the next 2 seasons. Save all your money for the draft, international free agent market, and in case Yu Darvish gets posted.
Dec 01, 2008 11:40 AM
Hey, back off Rickie Weeks! I want the OBP-challenged Reds to trade for him. ;)
Dec 01, 2008 11:22 AM
If you need a CF and can play glove over bat, Franklin Gutierrez from the Indians wouldn't be a bad choice. There are some in the Cleveland org who think he's a better defensive CF than Grady Sizemore, and although he can't really hit righties well, he isn't Juan Pierre.
Dec 01, 2008 11:39 AM
I am one of those who agrees that Gut is better than Sizemore defensively; about equal getting to the ball with a better arm. But he has little future in Cleveland. The organization likes Francisco and Choo for their bats, and have Crowe, Brantley and LaPorta (likely to end up at 1B) at AAA. I think that Cleveland would trade Gutierrez for pitching.
Dec 02, 2008 20:30 PM
Good article Joe, and I'm impressed that you reminded us that you supported the Andruw Jones signing last winter. I wish more columnists would admit when they are wrong. I do think the Dodgers can get away with Kemp in center. I'm not a scout, but he seems more comfortable there than in right. I'm not saying he's a great defensive center fielder, but he's better than the alternatives. It's no sure thing Weeks would be decent.
Dec 01, 2008 11:45 AM
I would love to see what you would do to fix the mess Minaya has made in Queens. I am a lifelong Mets fan in LA, so I am a familar with Dodgers. I like the idea of bringing Weeks out west, but I feel the Brewers would want something more substantial.
Dec 01, 2008 11:47 AM
Scott Jones
Good article.
Dec 01, 2008 12:04 PM
Hey Joe,
Dec 01, 2008 12:18 PM
Dec 01, 2008 15:35 PM
Dec 01, 2008 15:59 PM
You have a backup plan of moving Weeks back to 2nd to platoon with Durham if he doesn't pan out in CF, but then who plays CF? With the roster you developed, it seems like you end up playing Pierre again.
Dec 01, 2008 12:13 PM
Joe Sheehan
BP staff
That, or you move Kemp back there and fake left field (with Ethier in right). What's the saying about war? No battle plan survives contact with the enemy?
Dec 01, 2008 12:19 PM
Is it really a "fake" in LF to put Delwyn Young there and see how his bat plays? Given he's not a gazelle out there, but he's got more pop in his bat than anyone else in the system that hasn't had a decent chance yet and he's shown the ability to hit and get on base in the bigs.
Dec 02, 2008 08:07 AM
M-E-T-S...Mets, Mets, Mets! Omar can't do it...what about Joe?
Dec 01, 2008 12:19 PM
The problem with re-signing Lowe is that he is determined to go back east to play, and has made it clear to the Dodgers and their beat writers that he does not want to return to LA. According to MLB.com's Ken Gurnick, Lowe didn't even want to play in LA when he signed with the Dodgers four years ago, but he did sign because their contract offer was far better than anything else he could get. This off-season, Boston and the two New York teams are all interested in Lowe, so he is not going to have to accept playing out west for a lack of good offers.
Dec 01, 2008 12:27 PM
Wow, how much better would this roster look if the Dodgers had NOT traded Andy Laroche?
Dec 01, 2008 12:36 PM
Try Seattle Joe.
Trade 'em all for whatever you can get, spend all your money on the draft and the international market. Pretty much what John From Bel Air said in reference to the Giants.
Dec 01, 2008 16:01 PM
Jim Ferguson
I'm a Giants fan, but would probably not like to see the best you could do as GM for a day there. I'd like to see what you would do with two of the other problematic franchises at the moment: Texas and Baltimore
Does everyone think Weeks would come that cheap? I would think he would cost more, Melvin isn't stupid.
Not to quibble with what's a fine article, but in regards to home-grown/signed talent on the field in 2009. Youklis, Pedroia, Ellsbury, Lowrie, Lester, Daisuke, Buchholz, Papelbon, Delcarmen, Masterson, Okijima, and perhaps Bowden seems to match up quite well with the Dodgers group. In a not-so shocking related note, take on Theo's chair in the next week. I keep reading that Teixera is a 'perfect fit' for Boston. While his skill set is certainly a 'perfect fit' with the Red Sox philosophy, I'm quite sure their current 1B just finished 3rd in the MVP voting, the current DH has finished in the Top 5 for MVP 5 of the last 6 years, and the current 3B is a 2007 World Series MVP with Gold Glove caliber defense. Not to mention that two of those three are untrade-able at the moment due to injury. So 'perfect fit' seems a tad overstated to me.
Dec 01, 2008 12:41 PM
The Red Sox do have a very nice home-grown core, but giving them credit for "developing" Matsuzaka and Okajima is overly generous.
Dec 01, 2008 13:50 PM
I am not so sure I like the Weeks move. LA needs a power hitter in that lineup....sign Manny or CC. Ned has approximately $60mm to spend this offseason, and has the Schmidt and Jones contracts coming off next offseason....total of about $100mm over two seasons. Spend.
Dec 01, 2008 12:42 PM
Fresh Hops
I think Seattle is a nice choice for a next piece. I heard you almost made their short list when they went looking for a new GM.
Dec 01, 2008 12:47 PM
Do the Jays
Dec 01, 2008 12:48 PM
Dec 01, 2008 16:13 PM
I think the most interesting teams to do are those for whom it is unclear whether they should go for the gold or rebuild. In the AL, Toronto, Cleveland, Detroit and (if we didn't already see their direction) Oakland are the best candidates for this kind of column, in my opinion.
Dec 01, 2008 12:51 PM
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I know this is probably a silly idea, but could Pierre play 2B?
Dec 01, 2008 12:54 PM
As a lefty thrower, Pierre would be a very unorthodox second baseman.
Dec 01, 2008 13:05 PM
oh, and I'd love to see the my Mets in an similar article
Dec 01, 2008 12:55 PM
I think the most interesting teams to tackle are those that underperformed (whether compared to PECOTA or other expectations) and see what could be done to put those teams in contention next year. The Indians, Tigers, Mets or even Braves would seem to fit this criteria.
Dec 01, 2008 13:00 PM
The Cleveland Indians. Several persistent areas need to be addressed, what to do with the bullpen, team stuck in the middle, etc. Thanks.
Dec 01, 2008 13:05 PM
The Twins have a pretty strong group of internal homegrown talent:
Dec 01, 2008 13:08 PM
On Weeks-as a leadoff hitter-is he any better than Pierre? Weeks had a .327 obp last year. I don't like the idea of Weeks at all
Dec 01, 2008 13:19 PM
Two questions/comments:
Dec 01, 2008 13:34 PM
Looking at your proposed Dodgers lineup, I still see a group of 5,6,7 or 8 hitters. One middle of the order impact bat could make a difference here (as Manny proved last season). A team with this much money and young talent should be able to go get that guy, whether it be Manny or someone else. On another note, I will continue to hope that by some miracle Andruw Jones becomes part of the solution instead of the problem, as I also loved the signing last year.
Dec 01, 2008 13:37 PM
joe- make some sense of the mets. Apparently no one else can. I'm hearing idiocy like "trade beltran" for a couple of b players. Please stop the nonsense!
Dec 01, 2008 13:41 PM
I feel like some team out there would be willing to exchange another bad contract for Andruw Jones. Mabye Castillo from the Mets or Johjima from the Mariners (reliable back-up catcher). Or even Schmidt or Pierre ... oh wait...
Dec 01, 2008 13:44 PM
"I feel like some team out there would be willing to exchange another bad contract for Andruw Jones. Mabye Castillo from the Mets... "
Dec 02, 2008 12:21 PM
This piece is awesome, Thanks Joe. Although your plan is great, I bet most of them are not going to happen and will get worse since their GM is Ned Colletti. I nominate the Nationals.
Dec 01, 2008 13:47 PM
I like these articles very much. I vote for Joe to tackle the Giants next.
Dec 01, 2008 14:11 PM
If your favorite team signs the best free agent pitcher who's been on the market in the last five years to a contract you're going to turn your back on them? Please explain.
Dec 01, 2008 16:05 PM
What, you mean you'd want a rotation headlined by Sabathia, Lincecum and Cain? Who would want that?
Dec 01, 2008 21:40 PM
Why dump a ton of money on one FA pitcher - no matter how good he is - when the Giants have holes all over the lineup? It's tough to win if you can't score. And there surely is a bitter taste remaining from the Zito contract, one that will linger for several more seasons.
Dec 02, 2008 05:44 AM
"Why dump a ton of money on one FA pitcher - no matter how good he is - when the Giants have holes all over the lineup?"
Dec 02, 2008 08:38 AM
Good article Joe. How about signing Randy Johnson & Pedro and hope to get a total of 25 starts between them? I'd like to think Pedro would be a good mentor to the young pitchers. I would try to sign Dunn for 2 years and trade Ethier while his value is at its highest.
Dec 01, 2008 14:34 PM
I'd love to see you do the Mets as well, being as I'm a Phillies fan.
Dec 01, 2008 14:43 PM
Trade Xavier Paul and Victor Garate to the Brewers for Rickie Weeks; then make Weeks a center fielder
Dec 01, 2008 14:58 PM
The White Sox should be written about...several veterans who are on the block, large holes (center field, second base) to fill, a team coming off of a division title that could look nothing like that winning team.
Dec 01, 2008 15:24 PM
Joe: Fantastic idea. You need to do every team! Parcel it out if you have to, but I can't think of a better off-season feature. We're all doing it too, and we want to see if we dug up things the BP experts didn't!
Dec 01, 2008 15:26 PM
Dec 01, 2008 15:41 PM
Dec 01, 2008 16:00 PM
Morris Greenberg
Nice article Joe. I know people have already requested this but can you please do the Giants? The NL west is still weak and the Giants could maybe even make the playoffs if they play their cards right this winter. Also, I think the Giants might put out as much young players as the Dodgers on their roster just because of their emphasized youth movement and lack of talent in general.
Dec 01, 2008 19:32 PM
"The kids are growing into their own, it's true, but let's not forget that a big reason many of them took leaps last year was because they were hitting with THE most legitimate offensive threat in baseball for the last three months of the season."
Dec 01, 2008 20:37 PM
Love the Article Joe, although I can't see them not signing a starter this off season. How about a challenge for your next teams...Reds, Nationals or Giants.
Dec 01, 2008 21:47 PM
Nit pick alert:
Dec 02, 2008 09:50 AM
I agree with pmhawkins. The proposed Dodger lineup is nothing special. For that lineup to score a lot of runs, Ethier, Kemp, or Loney would have to be a legitimate MVP candidate. Possible, but not something I would bank on.
Dec 02, 2008 13:45 PM
As a lifelong Dodger fan, I'll say up front that Joe is smarter than me, but that lineup still looks way to pre-Mannyish.
Dec 02, 2008 18:43 PM
Ok need to have Manny third there:
Dec 02, 2008 18:46 PM
Joe, I'd like to see you pick another top team (Red Sox, Rays, Phillies, Cubs), one bad team with potential (Royals, Pirates), and 2 mediocre teams with a decent chance of contending (Indians, Reds, A's, Rockies among others) as your other choices. Teams like the O's, M's and Nats have so many holes, it's very difficult to put together a cohesive plan. I'd like to see the comparison between another top team and the Dodgers to see if there is really a need to make significant changes even if successful. And I'd like to see teams that may be contenders reviewed, even if it isn't obvious they are contenders now, but the possibility exists with a few moves (and I'm not talking sign CC, Teix, and Burnett). Sometimes it's the little moves that make all the difference. Like when the Red Sox signed two 1B/DH types in the 2002 offseason named Jeremy Giambi and David Ortiz, or when the Rays picked Carlos Pena off of the scrapheap 2 years ago.
Dec 02, 2008 19:48 PM
How about profiling the Brewers next?
Dec 02, 2008 19:51 PM
Domenik Hixon
I'd let Manny walk. The outlay and the headache are going to outweigh his benefit for a deal exceeding two years in length. Instead, and given that the White Sox are now apparently in rebuilding mode, how about sending Scott Elbert and Hu to the Sox for Jermaine Dye (11mm through 2009 with a mutual option for 2010)?
Dec 03, 2008 09:24 AM
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Race for the Cure 2012
On Saturday, October 27, the Lipscomb Academy softball team participated in the Susan G. Komen Race for the Cure 5K as a service project. The Susan G. Komen Race for the Cure Series, the largest series of 5K runs/fitness walks in the world, raises significant funds and awareness for the fight against breast cancer, celebrates breast cancer survivor-ship and honors those who have lost their battle with the disease.
Up to 75 percent of the funds raised at the Komen Greater Nashville Race for the Cure is used in Nashville's surrounding 11-county service area to provide screenings, treatment, services and education for uninsured or underinsured women. The remaining 25 percent goes to fund international, ground-breaking research to discover the causes of breast cancer and, ultimately, its cures.
After conditioning since the end of August, the softball players and their families participated in the 5K. Even though it was a cool 45 degrees, windy and misty at 8:30 on Saturday morning, everyone was in great spirits. The race began at 9:00 and the runners weaved through parts of Maryland Farms in Brentwood.
"It was so much fun and I loved training as a team. Knowing that we had a goal in mind helped us push through and grow closer," said senior outfielder Janie Lynn Lankford.
"I was extremely proud of the girls and I think they felt a sense of accomplishment not only for themselves finishing the 5K but being able to support such a great organization and cause," said head softball coach, Lexi Myers.


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Apparently the Dallas Morning News attended a different rally last night than me. At the rally The DMN attended, all the LGBT community did was complain about Democrats. There was no mention of the Texas Republican platform. There was no mention of the hatred from religious extremists going on across the street. No mention of the success last week at the DART board meeting. No mention of the Rainbow Lounge Raid. No remembrance of Harvey Milk or other hate crime victims.
Nope. Just non-stop complaining about Democrats.
At the rally I attended, one banner read, "Dems: Keep your promises."
One. That's it.
But signs accused homophobes of murder and demanded equality now.
After savagely ridiculing the Republican platform and skewering the handful of protesters blaring hatred on bullhorns across the street, Daniel Cates did have a line for some Democrats who are bowing to right-wing pressure.
"The time has come to lead or get out of the way," he said.
One line.
But from the Morning News article, the rally was a Democrat-bashfest.
What happened?
Several of the speakers asked me if I thought it was odd that the Morning News contacted them ahead of time. I answered that if a writer didn't report regularly on LGBT issues, he was just doing his homework so he'd be up on the issues and concerns of the community when he got there. That's just being prepared.
But that's not what happened. The DMN article doesn't quote what any speaker said during the rally. The article might quote what some of them said ahead of the rally. On the phone.
But not one quote FROM the rally. Not one chant from the parade route. Not one answer to the religious extremists.
So according to the Morning News, the rally was all about bashing the Democrats. Interesting, because it would have been hard to find a single Republican in the crowd. And if there were any Republicans there, other than the reporter whose piece could be used as a Republican Party press release and the counter-demonstrators across the street, it sure didn't seem like they were very excited about the current Texas Republican Party with its platform calling for making criminals out of LGBTA people.
Read our coverage of the march and rally by going here.


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Tony Award Winners Join BULLETS OVER BROADWAY Creative Team; Scenic Design by Santo Loquasto, Costumes by William Ivey Long and More
Producers Letty Aronson and Julian Schlossberg have just announced a creative team of award winning Broadway veterans for the world premiere production of Bullets Over Broadway, the new Broadway musical adaptation of Woody Allen's and Douglas McGrath's screenplay of the 1994 film.
Tony Award® winners Santo Loquasto (scenic design), William Ivey Long (costume design), Donald Holder (lighting design) and Glen Kelly (musical arrangements and supervision) will join five time Tony Award® winning director and choreographer Susan Stroman in bringing the new musical to the stage.
The Broadway production of BULLETS OVER BROADWAY, with an adaptation by Woody Allen, will feature existing music of the period when it arrives home on Broadway in the 2013 - 2014 season.
Additional creative team, dates, theater and casting will be announced shortly.
BULLETS OVER BROADWAY tells the story of an aspiring young playwright newly arrived on Broadway in 1920's New York who is forced to cast a mobster's talentless girlfriend in his latest drama in order to get it produced.
Santo Loquasto (Set Designer). Designer for theatre, film, dance and opera has won 3 Tony Awards® and has been nominated 15 times. He has collaborated with Woody Allen on more than 24 films, including costume design for Zelig and production design for Radio Days and Bullets Over Broadway for which he received Academy Award® nominations. Recent designs include Waiting for Godot, Fences and Wit. He received the Merritt Award for Excellence in Design and Collaboration in 2002, was inducted into the Theatre Hall of Fame in 2004 and received the Pennsylvania Governor's Award for the Arts in 2006 and the Robert L.B. Tobin Award for Lifetime Achievement in 2007.
William Ivey Long (Costume Design) previous collaborations with Susan Stroman include The Producers, Contact, Crazy For You, The Music Man, Young Frankenstein, Happiness, The Frogs, Thou Shalt Not, Steel Pier, Big, Picnic, A Christmas Carol at Madison Square Garden, Double Feature, Blossom Got Kissed and Frankie and Johnny Rose at New York City Ballet, as well as The Producers: The Movie Musical. Current Broadway: The Mystery of Edwin Drood, Chicago (now in its 17th year). Upcoming Broadway: Rodgers & Hammerstein's Cinderella, Big Fish (also with Ms. Stroman). Mr. Long has 12 Tony Award® nominations, winning 5 times. He was inducted into the Theatre Hall of Fame in January 2006, and elected Chairman of the American Theatre Wing in June 2012.
Donald Holder (Lighting Design) is currently represented on Broadway with The Lion King (Tony®, Drama Desk, Outer Critics Circle Awards), Spiderman Turn Off The Dark and the revivals of Annie and Golden Boy. Other Broadway credits include: Ragtime; Les Liaisons Dangereuses; A Streetcar Named Desire; Gem of the Ocean; Movin' Out; Juan Darien (all Tony Award® nominated), The Motherf**ker With the Hat; Promises, Promises; Arcadia; Come Fly Away; Cyrano de Bergerac; Radio Golf; The Little Dog Laughed; Thoroughly Modern Millie; Prelude to a Kiss; The Boy From Oz. Off-Broadway includes Blood and Gifts, Birdie Blue, Jitney, Saturday Night, Three Days of Rain, Jeffrey, Spunk, many others. TV: "Smash" (Seasons 1 and 2, NBC/DreamWorks).
Glen Kelly (Music Arrangements and Supervision) is currently represented on Broadway with A Christmas Story The Musical. Music supervisor and arranger for The Producers, Young Frankenstein and Mike Nichols' Death of a Salesman. He also arranged music for The Book of Mormon, The Scottsboro Boys, Spamalot, The Drowsy Chaperone, Beauty and the Beast, Frogs, Steel Pier and several others. For NYCB, he arranged the music and co-wrote the libretto for Double Feature. Other ballet credits: Thou Swell (for NYCB) and But Not for Me for the Martha Graham Company.
Susan Stroman (Direction/Choreography) A five-time Tony Award® winning director and choreographer, her work has been honored with Olivier, Drama Desk, Outer Critics, Lucille Lortel, and a record five Astaire Awards. She recently directed and choreographed the critically acclaimed musical The Scottsboro Boys, receiving Tony Award® nominations for both direction and choreography. She directed and choreographed The Producers, winner of a record-making 12 Tony Awards® including Best Direction and Best Choreography. She co-created, directed and choreographed the Tony Award® winning musical Contact for Lincoln Center Theater, which was honored with a 2003 Emmy Award® for Live at Lincoln Center. Other Broadway credits include Crazy for You, Show Boat, Oklahoma!, Young Frankenstein, The Frogs, The Music Man, Thou Shalt Not, Steel Pier, Big, Picnic. Off-Broadway credits include Happiness for Lincoln Center Theater, Flora the Red Menace, And the World Goes 'Round. For ten years she choreographed Madison Square Garden's annual spectacular A Christmas Carol, directed by Mike Ockrent. At New York City Opera she choreographed A Little Night Music, 110 in the Shade, and Don Giovanni. For New York City Ballet, she created Double Feature, a full-length ballet featuring the music of Irving Berlin and Walter Donaldson, and For the Love of Duke, featuring the music of Duke Ellington. Her other ballet credits include But Not For Me for the Martha Graham Company and Take Five…More or Less for Pacific Northwest Ballet. Her choreography received an Emmy Award® nomination for the HBO presentation "Liza – Live from Radio City Music Hall," starring Liza Minnelli. Other TV credits include co-conceiver/choreographer for PBS's "Sondheim – a Celebration at Carnegie Hall," "An Evening with the Boston Pops – A Tribute to Leonard Bernstein" and the "2009 Kennedy Center Honors". She received the American Choreography Award for her work in Columbia Pictures feature film Center Stage. She directed and choreographed The Producers: The Movie Musical, nominated for 4 Golden Globes. She is the recipient of the George Abbott Award for Outstanding Achievement in the Theatre.


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Arrange the shapes in a line so that you change either colour or
shape in the next piece along. Can you find several ways to start
with a blue triangle and end with a red circle?
This activity challenges you to make collections of shapes. Can you
give your collection a name?
What do you think is the same about these two Logic Blocks? What
others do you think go with them in the set?


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"Today, in a separate news release, we announced that following our request to discuss changes in our clinical development program because of dose related safety involving venous thromboembolic events, FDA notified the Company in a telephone call on Friday, February 17 that it was placing a clinical hold on our Phase II clinical studies of Capesaris® for first line treatment of advanced prostate cancer and secondary hormonal therapy," said Mitchell S. Steiner, MD, CEO of GTx. "We believe there may be a path forward to develop Capesaris at lower doses to treat men with metastatic hormone sensitive prostate cancer or castration resistant prostate cancer, and we plan to work with the agency to design appropriate studies for these patient populations."
"We are pleased with the progress of our clinical development program of enobosarm, formerly known as Ostarine(TM)," Dr. Steiner said. "Our discussions with lung cancer thought leaders and patient advocates confirm the need for a drug to prevent and treat muscle wasting in patients with advanced non-small cell lung cancer."
Clinical pipeline updates
* Enobosarm (Ostarine(TM), GTx-024), an oral selective androgen receptor modulator, for the prevention and treatment of muscle wasting in patients with non-small cell lung cancer: GTx was granted the generic name "enobosarm" for Ostarine as a first in class agent. GTx has recently commenced two pivotal Phase III clinical trials, POWER1 and POWER2 (Prevention and Treatment Of Muscle Wasting in CancER) in patients with advanced non-small cell lung cancer. These clinical trials were designed based on feedback from the United States Food and Drug Administration (FDA). In the fourth quarter, GTx met with representatives of the Medicines and Healthcare Products Regulatory Agency (United Kingdom) and Medical Products Agency (Sweden), who confirmed that the design of the POWER1 and POWER2 clinical trials should be sufficient for the European Medicines Agency to support registration in Europe. These international studies are being conducted in clinical sites in the United States, Europe, and South America. In each of the placebo-controlled, double-blind clinical trials, 300 patients with Stage III or IV non-small cell lung cancer will be randomized to placebo or enobosarm 3 mg at the time they are to begin first line chemotherapy. The studies are evaluating as co-primary endpoints after three months of treatment the effect of enobosarm versus placebo on maintaining or improving total lean body mass (muscle) assessed by dual x-ray absorptiometry (DXA) and on improvement of physical function assessed by the Stair Climb Test. Durability of the drug effect is being assessed as a secondary endpoint after five months of treatment. GTx expects data from the POWER1 and POWER2 Phase III clinical studies in the first quarter of 2013.
* Capesaris(R) (GTx-758), an oral selective estrogen receptor alpha agonist, for first and second line hormonal treatment of advanced prostate cancer prior to chemotherapy: GTx announced today that the FDA notified the Company in a telephone call on Friday, February 17, 2012, that the agency has placed a clinical hold on clinical trials evaluating Capesaris (GTx-758) for primary (first line) androgen deprivation therapy for advanced prostate cancer and secondary (second line) hormonal treatment. A clinical hold is a notification issued by the FDA to the trial sponsor to delay a clinical trial or suspend an ongoing clinical trial. The Company plans to work with the FDA to determine the appropriate path forward to evaluate Capesaris for the treatment of men with metastatic hormone sensitive prostate cancer or castration resistant prostate cancer.
Financial highlights for the quarter and year ended December 31, 2011
The net loss for the quarter ended December 31, 2011 was $10.7 million compared to a net loss of $7.5 million for the same period in 2010 reflecting increased research and development costs in connection with the Company's enobosarm and Capesaris clinical development programs. The net loss for the year ended December 31, 2011 was $33.3 million compared to net income of $15.3 million for the year ended December 31, 2010.
Revenue was $1.8 million for both of the quarters ended December 31, 2011 and 2010. Revenue for the fourth quarter of 2011 consisted of net sales of FARESTON(R) (toremifene citrate) 60 mg, approved for the treatment of metastatic breast cancer in postmenopausal women. Revenue for the fourth quarter of 2010 consisted of net sales of FARESTON(R) of $1.5 million and collaboration revenue of $336,000 from our former collaboration with Ipsen Biopharm Limited.
Revenue for the year ended December 31, 2011 was $14.7 million compared to revenue of $60.6 million for the year ended December 31, 2010. Revenue for the year ended December 31, 2011 included net sales of FARESTON(R) of $6.7 million and collaboration revenue from Ipsen of $8.1 million as a result of the termination of our license and collaboration agreement with Ipsen in March 2011. Revenue for the year ended December 31, 2010 consisted of net sales of FARESTON(R) of $3.8 million, collaboration revenue from Ipsen of $1.9 million, and collaboration revenue from Merck & Co. of $54.9 million resulting from the termination of our license and collaboration agreement with Merck in March 2010.
Research and development expenses for the quarter and year ended December 31, 2011 were $8.9 million and $31.9 million, respectively, compared to $5.8 million and $28.5 million for the same periods in 2010. General and administrative expenses for the quarter and year ended December 31, 2011 were $3.4 million and $15.4 million, respectively, compared to $4.5 million and $17.4 million for the same periods in 2010.
At December 31, 2011, GTx had cash, cash equivalents and short-term investments of $74.4 million.
Conference call
There will be a conference call today at 9:00 a.m. Eastern Time to discuss the latest development regarding Capesaris(R), provide a corporate update and discuss the Company's fourth quarter and full year 2011 financial results. To listen to the conference call, please dial 866-356-4279 from the United States or Canada or 617-597-5394 from other international locations. The access code for the call is 91296419. A playback of the call will be available from approximately 11:00 a.m. Eastern Time today through March 6, 2012, and may be accessed by dialing 888-286-8010 from the United States or Canada or 617-801-6888 from other international locations and referencing reservation number 84768366. Additionally, you may access the live and subsequently archived webcast of the conference call from the Investor Relations section of the Company's website at http://www.gtxinc.com .
Please note that the conference call previously announced to provide a corporate update and discuss the Company's fourth quarter and full year 2011 financial results to take place at 9:00 a.m. Eastern Time on Wednesday, February 22, 2012 has been cancelled.
About GTx
GTx, Inc., headquartered in Memphis, Tenn., is a biopharmaceutical company dedicated to the discovery, development, and commercialization of small molecules that selectively target hormone pathways for the treatment of cancer, cancer supportive care, and other serious medical conditions.
Forward-Looking Information is Subject to Risk and Uncertainty
This press release contains forward-looking statements based upon GTx's current expectations. Forward-looking statements involve risks and uncertainties, and include, but are not limited to, statements relating to GTx's clinical trials for enobosarm (also known as Ostarine(TM) or GTx-024) and Capesaris(R) (GTx-758), including statements relating to whether there may be a path forward to develop Capesaris at lower doses to treat men with metastatic hormone sensitive prostate cancer or castration resistant prostate cancer, the timing of discussions with the FDA regarding the current clinical hold and whether or under what additional requirements, if any, further clinical development will be permitted. GTx's actual results and the timing of events could differ materially from those anticipated in such forward-looking statements as a result of these risks and uncertainties, which include, without limitation, the risks (i) that GTx will not be able to commercialize its product candidates if clinical trials do not demonstrate safety and efficacy in humans; (ii) that GTx may not be able to obtain required regulatory approvals to commercialize its product candidates in a timely manner or at all; (iii) that clinical trials being conducted by GTx may not be completed on schedule, or at all, or may otherwise be suspended, similar to the clinical hold announced today on Capesaris, or terminated; or (iv) that GTx could utilize its available cash resources sooner than it currently expects and may be unable to raise capital when needed, which would force GTx to delay, reduce or eliminate its product candidate development programs or commercialization efforts. You should not place undue reliance on these forward-looking statements, which apply only as of the date of this press release. GTx's quarterly report on Form 10-Q filed with the Securities and Exchange Commission on November 4, 2011 contains under the heading, "Risk Factors", a more comprehensive description of these and other risks to which GTx is subject. GTx expressly disclaims any obligation or undertaking to release publicly any updates or revisions to any forward-looking statements contained herein to reflect any change in its expectations with regard thereto or any change in events, conditions or circumstances on which any such statements are based.
SOURCE: GTx, Inc.
GTx, Inc.
McDavid Stilwell, 901-523-9700
Director, Business Development & Corporate Communications


text: +-------------------------------------------------------------------------+ | TPWD News Release 20090618a | +-------------------------------------------------------------------------+ | This page contains only plain text, no HTML formatting codes. | | It is not designed for display in a browser but for copying | | and editing in whatever software you use to lay out pages. | | To copy the text into an editing program: | | --Display this page in your browser. | | --Select all. | | --Copy. | | --Paste in a document in your editing program. | | If you have any suggestions for improving these pages, send | | an e-mail to email@example.com and mention Plain Text Pages. | +-------------------------------------------------------------------------+ [ Note: This item is more than eight years old. Please take the publication date into consideration for any date references. ] [ Media Contact: TPWD News, firstname.lastname@example.com, 512-389-8030 ] [RM] June 18, 2009 Texas State Parks Showing Patriotic Fervor AUSTIN, Texas -- From two diamond anniversary celebrations and fireworks extravaganzas to live music performances and bicycle parades, more than a dozen Texas state parks are planning a host of special events to commemorate the Fourth of July holiday weekend. Two of Texas' oldest and best known state parks -- Palo Duro Canyon in the Texas Panhandle and Caddo Lake in the northeastern corner of the state -- will celebrate 75 years of welcoming the public to some of the Lone Star State's most spectacular natural wonders. Both parks were developed in 1934 by the Civilian Conservation Corps, one of President Franklin D. Roosevelt's most ambitious public works programs instituted during the Great Depression era. Palo Duro Canyon State Park's 75th anniversary celebration stretches over two days, with Saturday, July 4, events including a special daytime program on the canyon's history and the Independence Day version of the renowned outdoor musical drama, "Texas!" that night. Park entry fees are waived. On Sunday, in the same Pioneer Amphitheater, music fans will be treated to a rare concert by Texan-born music legend Boz Scaggs and his band. Amarillo's famous Big Texas Steak Ranch will cater both events. Tickets for both nights' entertainment can be purchased by visiting http://www.texas-show.com/ or by calling (806)655-2181. Caddo Lake State Park & Wildlife Management Area will commemorate the park's opening on July 4, 1934, from 10 a.m. to 3 p.m. with a special program on the CCC and Caddo Indians that will include traveling exhibits, the unveiling of a time capsule buried 15 years ago and collection of items for burial in a new time capsule to be recovered at the park's 150th anniversary in another 75 years. Local park supporter Mary Jane Sanders, who attended the original park opening in 1934, has been invited to share stories of the park's early days. The state park gets its name from 26,000-acre Caddo Lake, a sprawling maze of cypress swamps, bayous and slough that once comprised the only natural lake in Texas until it was dammed below. It was the state's first planned CCC park project with land acquisition beginning in 1933. The original recreation hall and cabins still stand. Cabin 1, renovated in 2001, will be open for tours during the celebration. Several local organizations, including the Caddo Lake Institute and City of Uncertain, will have booths set up at the event. Day use fees will be waived on July 4 for visitors attending the 75th anniversary event. For more information, call (903) 679-3351. The seat of Texas independence -- Washington-on-the-Brazos State Historic Site between Navasota and Brenham -- will host a full day of 4th of July events from 10 a.m. to 10 p.m., culminating with "Fireworks on the Brazos" presented by H-E-B. Festivities will include strolling Western entertainers, a Kid Zone, free music concerts at the amphitheater, a performance by the Brenham Children's Chorus and at 7 p.m. free Blue Bell ice cream and Coca-Cola. The celebration event is free, but tour fees apply. Call (936) 878-2214 for details. Another Texas Parks and Wildlife Department-operated site -- the Texas Freshwater Fisheries Center in Athens -- will host "Fireworks at the Fishery" on July 4. What is touted as one of the largest fireworks displays in East Texas will follow a day of free fishing. Call (903) 676-BASS for more information. Several state parks will be hosting traditional holiday activities. Kids can decorate their bikes for 4th of July parades through Inks Lake, Martin Dies Jr. and Purtis Creek state parks, and participate in sack races, egg relays and three-legged races at the World Birding Center at Estero Llano Grande State Park. (See detailed listings below) "Fourth of July in the 1900s" at Lyndon B. Johnson State Park and Historic Site will feature traditional German family holiday fun such as horseshoes, washer pitching and stickhorse races. Historical houses and buildings will be open for guided tours by interpreters dressed in period clothing during the 10 a.m. to 3 p.m. event. Call (830) 644-2252 for information. Other state parks hosting July 4 festivities include: --Cedar Hill SP -- Celebrating Our Flag -- Honor America through the retirement of our country's flag. Learn some of the history of the Star and Stripes; experience what it means to retire Old Glory in the proper manner. This will be an evening of patriotic poetry and music as we remember our struggle for independence and the men and women who serve our country to keep us free. This will be a great family program to experience on July 4th. Held at Penn Farm. 7-9 p.m., (972) 291-5940. (972) 291-3900. --Franklin Mountains SP -- Independence Day Celebration Hike -- After your cookout, hike the Upper Sunset Trail and enjoy the fireworks from afar! 7-9 p.m.; fee $7 adults, free for children 12 and under; reservations required, deadline one day prior (915) 566-6441. --Inks Lake SP -- Happy Birthday USA Bicycle Parade -- Kids, bring your bikes to the playground near the Park Store to decorate them for the parade. Parents and grandparents, you are welcome to attend and assist the kids. Make sure to bring your cameras and camcorders to record this memory-making event! We will parade through the park roads and show off the bikes. 10-11 a.m. (512) 793-2223. --Lake Texana SP -- Fourth of July Fun & Games -- Bring your picnic lunch and join us for some horseshoes, washer toss, volleyball, sack races, water balloon toss, dunking booth, and other fun games. Accessible for the mobility impaired. 2-4 p.m. (361) 782-5718 --Martin Dies, Jr. SP -- Fourth of July Patriotic Celebration -- Enjoy a fun-fill exciting day celebrating Independence Day with a decorated bike parade and patriotic events such as soaker-ball splash, paddle-ball count-down, beanbag toss, and temporary tattoos, with participants in all events winning prizes. A sing-along live concert is provided by park staff. All events are free and are sponsored by the Friends of Martin Dies, Jr. State Park. 2-4 p.m. (409) 384-5231. --Purtis Creek SP -- Parade in the Park -- Meet at the amphitheater and decorate your bike (materials provided or bring your own) then parade through the park. Prizes awarded to the best decorated bike. Meet back at the amphitheater for refreshments and games. 9 a.m.-noon (903) 425-2332. --World Birding Center -- Estero Llano Grande SP -- 4th of July Fest -- Pack up your favorite picnic foods, friends and family and head to the park for some holiday fun. You can compete in the classic picnic games of sack racing, egg relays and three-legged races. Also, the first 50 children to sign up will be able to paint their own birdhouses to take home. Accessible for mobility, visually and hearing impaired. 10 a.m.-3 p.m.; reservations required (956) 565-3919. --- On the Net: http://tpwd.texas.gov/newsmedia/calendar/?calpage=date -30-


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CHINO – Chino American Legion Post 299 will host bingo on Jan. 13, with doors open at noon and bingo starting at 1 p.m.
Snacks, sodas and water will be sold. All proceeds benefit veterans. In addition, breakfast is served at the post every Sunday from 9 a.m. to noon. Taco lunch is served every Tuesday from 11 a.m. to 2 p.m. The post is at 13759 Central Ave.
Information: 909-628-2080


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looking for both egon and Ray and Winston and peter 2 packs Big Lots has em for $30, I will pay above that for your trouble but please don't try to make too much off me. thanks!
CHECK OUT MY BRAND NEW WEBSITE for my Akil and Saltfish comic strip, more to come soon!
I've got everything that I need, right in front of me! Life's a happy song people!
Fear is faith in failure


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Piano Horn Aprons are an Idakoos specialtiy! Idakoos has many things to offer. Whether you want to get a Piano Horn Apron for a special occasion, give a Piano Horn Canvas Apron as a present or need to represent with a funny Piano Horn Apron during Holidays or Family and Friends get-togethers, Idakoos is sure to have the right Piano Horn Apron for you! Even if it turns out you can't find the right Piano Horn Canvas Apron with the perfect design for your mother, father or children (or friends!); Idakoos offers all of its Piano Horn Aprons as Custom Piano Horn Aprons. Personalize any Piano Horn Apron the way you want to ensure the perfect gift.
Showing 1 - 24 of 92 Apron


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FOREST Green boss Ady Pennock cut a frustrated figure as the lights went out at the New Lawn.
A section of the lights failed on the main stand side of the ground on the half-hour mark of his side's thrilling match against Grimsby, forcing the players to retreat to the dressing room with the scoreline locked at 1-1.
The players returned within 10 minutes, but 30 seconds after the game re-started the lights went again and the match referee abandoned the game.
Pennock said: "The players and myself are disappointed as it was a good game between two good teams.
"The Grimsby fans had come along way and they had to be taken into consideration, but obviously the game was called off because of the lights. The ref was also concerned about the pitch with the rain non-stop, but I am frustrated because we seem to be so stop-start at the moment with games being rained off and now this issue this evening."
Earlier, play-off chasing Grimsby had raced into a seventh-minute lead when Ross Hannah raced past Ed Asafu-Adjaye on the right and sent over a low cross for Lenell John-Lewis to thump past Sam Russell.
Pennock was unhappy with the goal his side leaked as his defence opened up like a knife through butter.
However, Rovers' riposte was immediate. Four minutes later veteran Lee Hughes held off his marker for James Norwood to rifle home from 20 yards for his 10th goal of the season.
It was end-to-end stuff. Rovers survived a scare when Aswad Thomas stepped on the gas and fed John-Lewis, who shot over.
Rovers rallied, Marcus Kelly fizzed over from distance and then a Jerome Binnom-Williams cross was headed over with Reece Styche racing in.
Russell blocked at the feet of Scott Neilson and the ball broke for John-Lewis, who sliced wide of an open goal.
Meanwhile, left-back Chris Stokes has resumed light-training with the squad. Elsewhere, the loan of talented defender Jerome Binnom Williams is expected to be extended. Pennock is set to contact boss Tony Pulis at his parent club Crystal Palace, today.
League One leaders Brentford are still keen on centre-back Eddie Oshodi, who played for Rovers last night, after spending a week on trial at Griffin Park.


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NORFOLK, Va. -- The offenses stole the show, but Georgia Southern's defense got the Eagles a spot in the FCS semifinals.
Jerick McKinnon ran for 171 yards and four touchdowns and Dominique Swope ran for 186 yards and two more scores, including the go-ahead touchdown that was set up by a turnover, as the Eagles outlasted Old Dominion 49-35 on Saturday.
Georgia Southern ran for 602 yards in all. Old Dominion gained 421 of its 534 through the air.
And the biggest play of the game? Defensive end Dion DuBose's strip of Old Dominion quarterback Taylor Heinicke with the Payton Award finalist at the Eagles' 13, trying to put the Monarchs two scores ahead. The ball was recovered by Patrick Flowe, and 12 plays and 79 yards later, McKinnon's 12-yard run pulled the Eagles even at 35.
"I give a lot of credit to my (defensive backs)," DuBose said. "If not for my DBs, I would have never gotten there."
On the ensuing series for Old Dominion, Heinicke threw incomplete on fourth-and-6 from his own 39, and it took the six-time national champions just three plays to cover those 39 yards. Swope's 12-yard run gave them a 42-35 advantage.
And finally, needing a touchdown drive to knot it again and with 2:36 to work with, Heinicke threw over the middle looking for Nick Mayers, and instead J.J. Wilcox intercepted it, setting up the final touchdown and sending Georgia Southern into the semifinals in search of their first national championship since 2000, and ending ODU's last chance to claim an FCS title.
The Monarchs are moving up to the FBS level next season as members of Conference USA.
"It was a battle. It was a fight, and our kids just kept slugging it out," first-year Eagles coach Jeff Monken said.
Of the interception, Wilcox said film work paid off.
"It happened just like practice, and I was just at the right spot at the right time," he said.
The Eagles (10-3), who completed just two passes all day, trailed 35-21 entering the final quarter.
Heinicke, who broke Steve McNair's single-season passing yardage record during the game, finishing with 5,076 for the year, and set another record with 398 completions, said his first turnover started a downward spiral for the Monarchs.
"Since that fumble I had in the red zone, it just went downhill from there," he said. "Momentum just shifted to their side and we never got it back. ... That was definitely what they needed on defense. They stole points from us."
Monarchs coach Bobby Wilder tried to console Heinicke, who finished the afternoon 31 of 44 for 421 yards with three passing touchdowns, including a 74-yarder to Antonio Vaughan, and 48 yards and one touchdown on the ground.
"He was crushed," Wilder said. "It's an almost laughable thing for me to say this, but he felt like he didn't do enough."
It was the second consecutive season the Eagles have dispatched the Monarchs (11-2) from the playoffs in a thriller. Last season, the Eagles won 55-48 at home.
This time, the Monarchs seemed in control when they stopped the Eagles on four consecutive drives spanning the halves and opened a 35-21 lead on Heinicke's third touchdown pass, 8 yards to Mayers, with 2:53 remaining in the third quarter. Earlier, he had hit Vaughan with the long one and Mayers from 5 yards.
The Eagles capped an 86-yard drive with McKinnon's 4-yard TD run on the first play of the fourth quarter, pulling within 35-28, then got the ball back on DuBose's strip of Heinicke on a third-and-7 play.


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Symantec Control Compliance Suite
Risk-prioritized data center security operations and compliance
Symantec Control Compliance Suite delivers business-aware security and risk visibility so that customers are effectively able to align priorities across security, IT operations, and compliance. It automates continuous assessments and delivers a unified view of security controls and vulnerabilities. Customers can harden the data center, prioritize security remediation, enable a secure migration to the software-defined data center, and support continuous assessments for Cyber Security and Continuous Monitoring.


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The Smokers Club is a team of hip-hop heavyweights that was initially put together for a single show at South by Southwest in 2010, but evolved into a lifestyle brand that makes dope tees and more. The original members of The Smokers Club include GFC New York's Steve-O, rappers Big K.R.I.T and Smoke DZA, Cinematic Music Group president Jonny Shipes, and Purple City Byrd Gang founder Shiest Bubz. With a fresh collection of designs that highlight 420 culture, Smokers Club is only getting started, and with affiliates like Joey Bada$$, Curren$y, Juicy J, and more, you can be sure that their footprint in the scene is going to continue to grow.
No products match your selections. Try clearing your filters.


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Emerging Currencies at Critical Juncture
How much easier it is to be critical than to be correct. --Benjamin Disraeli
I have been pounding the table recently in various writings and online media appearances that intermarket trends suggest we are either in a correction or on the verge of one as the Dow Jones Industrial Average clings to 14,000. On CNBC Friday, I laid out the case that there is very little confirmation of bullishness within the market, and that Nouveaux Bulls may begin to see a surprise decline soon. Behaviorally, the market is acting like a decline is soon to follow, disagreeing with absolute price action....223 more words left in this article. To read them, just click below and try Real Money FREE for 14 days.
There's no substitute for a trading floor to get great ideas, so Jim Cramer created a better one at Real Money and blogs there exclusively. We then added legendary hedge fund manager, Doug Kass, with his exclusive Daily Diary and best investing ideas. Staffed with more than 4 dozen investing pros, money managers, journalists and analysts, Real Money Pro gives you a flood of opinions, analysis and actionable trading advice found nowhere else, and allows you to interact directly with each expert.
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Now showing items 1-10 of 15
Cerebropulmonary dysgenetic syndrome
Ventilatory treatment of neonatal respiratory distress often results in bronchopulmonary dysplasia from congenital surfactant deficiency due to mutants of transporter protein ABCA3. Association of this condition with ...
On the pulmonary toxicity of oxygen. 4. The thyroid arena
Normally developed thyroid function is critical to the transition from fetal to neonatal life with the onset of independent thermoregulation, the most conspicuous of the many ways in which thyroid secretions act throughout ...
Roles for Drosophila melanogaster myosin IB in maintenance of enterocyte brush-border structure and resistance to the bacterial pathogen Pseudomonas entomophila
(American Society for Cell Biology, 2007-09-12)
Drosophila myosin IB (Myo1B) is one of two class I myosins in the Drosophila genome. In the larval and adult midgut enterocyte, Myo1B is present within the microvillus (MV) of the apical brush border (BB) where it forms ...
A global, myosin light chain kinase-dependent increase in myosin II contractility accompanies the metaphase–anaphase transition in sea urchin eggs
(American Society for Cell Biology, 2006-07-12)
Myosin II is the force-generating motor for cytokinesis, and although it is accepted that myosin contractility is greatest at the cell equator, the temporal and spatial cues that direct equatorial contractility are not ...
Letters to the Editor : Challenges of forensic science
Letters: Challenges Of Forensic Science. Published August 6, 2012
Thyroid and adrenal factors in hyaline membrane disease
Pulmonary fibrosis implies antecedent lung injury which may or may not include inflammatory responses of the ordinary sort. The onset of breathing at mammalian birth is a different kind of lung injury, one occasioned by ...
Argon and the pathophysiology of pulmonary oxygen toxicity
Molecular interaction can be determined from biological experiments. In the case of dynamics at the atmosphere-lung interface the physicochemical and atomic attributes of inhalant gases has significant biological and ...
Placental hypervascularity does not cause perinatal brain injury
Dizygotic twins at 38 weeks with separate placentas: twin A, a 2479 gram female, was healthy after vaginal delivery. Five minutes later when the amnion of twin B was ruptured artificially, the cord prolapsed and could not ...
Historical perspecitive on lead biokinetic models
(National Institute of Environmental Health Sciences, 1998-12)
A historical review of the development of biokinetic model of lead is presented. Biokinetics is interpreted narrowly to mean only physiologic processes happening within the body. Proceeding chronologically, for each epoch, ...
Central spindle self-organization and cytokinesis in artificially activated sea urchin eggs
(Marine Biological Laboratory, 2016-04)
The ability of microtubules of the mitotic apparatus to control the positioning and initiation of the cleavage furrow during cytokinesis was first established from studies on early echinoderm embryos. However, the ...


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Half a million people are expected to join shoots on the last day of the pheasant and partridge seasons tomorrow, says the Countryside Alliance.
Record numbers are expected to take advantage of the final day of the pheasant and partridge seasons.
The last day of the season is the beaters' day on many shoots, when those people who have worked throughout the season take their turn with a gun.
An estimated 25,000 shoots will take place around the country, with as many as 500,000 people - 200,000 guns and another 300,000 family and friends - getting involved and enjoying a day outside.
The Countryside Alliance says shooting plays a vital part in rural Britain, is worth more than £1.6 billion to the UK economy and supports 70,000 full-time jobs.
Barney White-Spunner, Countryside Alliance executive chairman, said: "Having so many people going out shooting on the final day of the season is a true success story, showing that support for shooting is stronger than ever.
"Come rain or shine, around half a million people will be enjoying the last day of the season in traditional style."
The Countryside Alliances says there are record sales of wild game in supermarkets this season. It has been reported that sales of rabbit are up 20 per cent in a year at Marks & Spencer and pheasant sales are up 30 per cent, while partridge sales have increased by 234 per cent.
Waitrose has said that its venison sales were up by 92 per cent year-on-year.


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Clean And Simple Collection by Minka Aire
The Clean and Simple Collection features four and five bladed, Minka-Aire ceiling fans. The Como and Supra ceiling fans have a simple design that goes well with the brushed steel color. For a bit more flair, consider installing the Zen and New Era ceiling fan. These fans have more color options, which helps to match the existing room furniture.


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Photograph courtesy Zeb Hogan
Fast Facts
- Type:
- Fish
- Diet:
- Omnivore
- Average life span in the wild:
- Males, 55 years; females, 150 years
- Size:
- 6.5 ft (2 m)
- Weight:
- Up to 200 lbs (90 kg)
- Did you know?
- The lake sturgeon is often called a "living fossil," part of a family of fish that has existed for more than 135 million years.
- Relative:
- Size relative to a 6-ft (2-m) man
Please add a "relative" entry to your dictionary.
The lake sturgeon, with its sleek shape and rows of bony plates on its sides, looks a bit like an armored torpedo. These freshwater giants have greenish-grey coloring and a pointed snout with two pairs of whiskerlike tactile organs that dangle near its mouth. These organs, called barbels, help it to locate bottom-dwelling prey, such as snails, clams, insect larvae, and fish eggs.
Lake sturgeons can be huge, topping six feet (two meters) long and weighing nearly 200 pounds (90 kilograms). They are also extremely long-lived. Males may live some 55 years, and females can reach 150.
Despite their name, lake sturgeons are also found in rivers, but they avoid salt water. These fish were once a major part of North America's Great Lakes, Hudson Bay, and Mississippi River ecosystems and occurred from Canada to Alabama. But intense fishing has exacted a heavy toll on their populations.
These fish were once killed as a nuisance bycatch because they damaged fishing gear. When their meat and eggs became prized, commercial fishermen targeted them. Between 1879 and 1900, the Great Lakes commercial sturgeon fishery brought in an average of 4 million pounds (1.8 metric tons) per year.
Such unsustainable catch rates were coupled with environmental challenges such as pollution and the construction of dams and other flood control measures. Sturgeons, which return each spring to spawn in the streams and rivers in which they were born, found tributaries blocked and spawning shoals destroyed by silt from agriculture and lumbering.
The 20th century saw drastic drops in sturgeon catches, increased regulations, and the closure of viable fisheries. Currently 19 of the 20 states within the fish's original U.S. range list it as either threatened or endangered.
In recent years, however, the great fish has made something of a comeback. Strong efforts at righting environmental wrongs in the Great Lakes have improved conditions, and concentrated efforts to protect the fish have turned sturgeon into a spotlight species.
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Flexible Hose Assy, 3/4-14 In, 60 In L
PENFLEX| Zoro #: G1710624| Mfr #: FTG-12-A-A-CS-60
Zoro #: G1710624Mfr. Part #: FTG-12-A-A-CS-60
$224.00 /ea
This item ships free. DetailsStandard ground shipping
Technical Specifications
|Zoro #: G1710624 Mfr #: FTG-12-A-A-CS-60
|Standards: CSA, CGA CR96-001
|Max. Temp. (F): 1500
|Max. Working Pressure (PSI): 350
|Braid Material: 304 Stainless Steel
|Item: Flexible Metal Hose Assembly
|Hose Material: 321 Stainless Steel
|Pipe Size (In.): 3/4-14
|Fitting Type: Carbon Steel MNPT
|Length (In.): 60
|Dia. (In.): 3/4
|Dynamic Min. Bend Radius (In.): 8
|Static Min. Bend Radius (In.): 2.25
|Country of Origin (subject to change): United States
Product Description
Flexible Metal Hose Assembly, Dia. 3/4 In, Length 60 In, Pipe Size 3/4-14 In, Max. Working Pressure 350 PSI, Static Min. Bend Radius 2.25 In, Dynamic Min. Bend Radius 8 In, Max. Temp. 1500 F, Fitting Type Carbon Steel MNPT, Braid Material 304 Stainless Steel, Hose Material 321 Stainless Steel, Standards CSA, CGA CR96-001
Restrictions and Compliance
- *1 : California Proposition 65 : This product contains a chemical known to the State of California to cause birth defects or other reproductive harm.
- *2 : California Proposition 65 : This product contains a chemical known to the State of California to cause cancer.
- This product is not intended for potable water applications (human consumption – drinking and cooking) and has not been designed to be compliant with the "Safe Drinking Water Act" requirements for low lead in potable water applications. This item is for use, only, in non-potable (non-human consumption) water applications.
- ***
- This is a restricted item. It cannot be used in the USA for potable water applications.