text:
FLT-PET Activity Change After Allogeneic Umbilical Cord Blood (UCB) Therapy in Cerebral Palsy
This study has been withdrawn prior to enrollment.
(Difficulty in obtaining specific isotope tracer)
Bundang CHA Hospital
Information provided by (Responsible Party):
MinYoung Kim, M.D., Bundang CHA Hospital
ClinicalTrials.gov Identifier:
First received: December 4, 2011
Last updated: November 17, 2013
Last verified: November 2013
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Detailed Description:
This is randomized placebo-controlled trial to recognize new cell regeneration in the brain using FLT-PET.
|Cerebral Palsy
|Biological: Umbilical Cord Blood Infusion Other: Active Rehabilitation Other: Placebo Umbilical Cord Blood
|Phase 2
|Study Type:
|Study Design:
|Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
|Official Title:
|FLT(3'-Deoxy-3'-[F-18]Fluorothymidine)-PET Activity Change After Allogeneic Umbilical Cord Blood Cell Therapy in Cerebral Palsy
Resource links provided by NLM:
MedlinePlus related topics: Cerebral Palsy Paralysis RehabilitationU.S. FDA Resources
Further study details as provided by MinYoung Kim, M.D., Bundang CHA Hospital:
Primary Outcome Measures:
- Comparison of FLT-PET Activity Change [ Time Frame: Baseline - 2 weeks ]Comparison of FLT-PET Activity Change between UCB group and Placebo group during 2 weeks: To compare differences in regional brain FLT-PET activity between groups and differences between pre- and post-therapy imaging data. The baseline and post-therapy data of each group will be compared using paired t-test statistics.
Secondary Outcome Measures:
- Changes in Neurodevelopmental Outcome [ Time Frame: Baseline - 2 weeks - 3 months ]Korean version of Bayley Scale of Infant Development-II (K-BSID-II) Motor and Mental Scales (Higher score means better motor and mental function).
- Changes in Standardized Gross Motor Function [ Time Frame: Baseline - 2 weeks - 3 months ]GMFM (Gross Motor Function Measure) as a standardized measurement tool for assessing Gross Motor Function consisting of sub-scales; lying & rolling, sitting, crawling & kneeling, standing, walking, running & jumping (range: 0~100 %, Higher score means better motor function).
- Changes in Quality of Movement [ Time Frame: Baseline - 2 weeks - 3 months ]GMPM (Gross Motor Performance Measure) as a standardized measurement tool for assessing quality of movement regarding 3 properties of 5 ones; alignment, coordination, dissociated movement, stability, and weight shift.
|Study Start Date:
|March 2013
|Estimated Study Completion Date:
|July 2014
|Estimated Primary Completion Date:
|April 2014 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: Umbilical Cord Blood & Rehabilitation
Allogeneic umbilical cord blood infusion and active rehabilitation
Biological: Umbilical Cord Blood Infusion
The subjects will be undertaken allogeneic umbilical cord blood infusion intravenously or intraarterially under non-myeloablative immunosuppression.
Other Name: Donated Umbilical Cord Blood Units from Affiliated Cord Blood BankOther: Active Rehabilitation
All subjects should participate in active rehabilitation. They will receive two physical and occupational therapy sessions per day. Post discharge, each participant continued to receive rehabilitation therapy at least 3 days per week for additional 2.5 months.
Active Comparator: Placebo Umbilical Cord Blood & Rehabilitation
Placebo Umbilical Cord Blood infusion and active rehabilitation
Other: Active Rehabilitation
All subjects should participate in active rehabilitation. They will receive two physical and occupational therapy sessions per day. Post discharge, each participant continued to receive rehabilitation therapy at least 3 days per week for additional 2.5 months.Other: Placebo Umbilical Cord Blood
Placebo Umbilical Cord Blood that resembles cord blood in appearance was designed : 1.5 to 3 ml of the subject's own blood was collected and mixed with 15 to 20 ml of albumin
Detailed Description:
FLT(3'-Deoxy-3'-[F-18]Fluorothymidine) has been developed as a cell-proliferation tracer. In animal study, FLT-PET was used as a tool that enables imaging and measuring of proliferation in the brain, thus it detects activity of endogenous neural stem cells noninvasively. This study aims to assess cell proliferation activity changes in the brain after Umbilical Cord Blood (UCB)Therapy for Cerebral Palsy patients using FLT-PET.
|Ages Eligible for Study:
|6 Months to 20 Years (Child, Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Cerebral Palsy
- Abnormal muscle tone
- Gross Motor Function Classification System (GMFCS): I, II, III, IV, V
- Willing to comply with all study procedure
Exclusion Criteria:
- Medical instability including pneumonia or renal function at enrollment
- Presence of known genetic disease
- Presence of drug hypersensitivity which is related to this study remedy
- Poor cooperation of guardian,including inactive attitude for rehabilitation and visits for follow-up
- Decision by the principal investigator when there are unexpected events including brain surgery, that may affect the outcome
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01486732
Please refer to this study by its ClinicalTrials.gov identifier: NCT01486732
|Korea, Republic of
|CHA Bundang Medical Center
|Seongnam-si, Gyeonggi-do, Korea, Republic of, 463-712
Sponsors and Collaborators
Bundang CHA Hospital
|Principal Investigator:
|Minyoung Kim, M.D., Ph.D.
|CHA University
More Information
Keywords provided by MinYoung Kim, M.D., Bundang CHA Hospital:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on September 18, 2017
|Responsible Party:
|MinYoung Kim, M.D., Associate Professor, Bundang CHA Hospital
|ClinicalTrials.gov Identifier:
|NCT01486732 History of Changes
|Other Study ID Numbers:
|Study First Received:
|December 4, 2011
|Last Updated:
|November 17, 2013
Keywords provided by MinYoung Kim, M.D., Bundang CHA Hospital:
Cerebral Palsy
Umbilical Cord Blood
Additional relevant MeSH terms:
Cerebral Palsy
Neurologic Manifestations
Nervous System Diseases
Signs and Symptoms
Brain Damage, Chronic
Brain Diseases
Central Nervous System Diseases
ClinicalTrials.gov processed this record on September 18, 2017


text:
James Franco may be a big star, but what he really want to do is direct -- a new William Faulkner adaptation.
The star of "This Is The End" told The Los Angeles Times on Monday that he's planning direct and star in an adaptation of "The Sound and the Fury," Faulkner's 1929 epic about a family of Mississippi aristocrats who fall on hard times.
Even better, he wants "Mad Men" star Jon Hamm to play family patriarch Mr. Compson.
The article said the movie could begin shooting as early as this autumn.
"The Sound and The Fury" was filmed in 1959 with Yul Brynner playing lead character Jason Compson.

subset: commoncrawl


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Hi Everyone!
Post your week here.
Hi Everyone!
Post your week here.
lol. Double weekly. I don't think it's happened before!
Too funny! Looks like we posted at the same time. Can't figure out how to delete it!
Decent week for me. Getting back in the groove.
M - 4 miles & abs workout
T - 3 miles & abs workout
W - 4 miles & abs workout
Th - 3 miles & abs workout
F - strength/core workout, yoga & abs workout
S - 6 miles
Su - SRD
Total - 20 miles
Even though it's not a Sunday yet (last day of my running week), I will have 0 miles for a second week in a row. Scheduled rest fo my body and mind after two successful marathons. But I am very excited that I start running this coming Monday.
M - 3.3@8:57 on flat dirt/grass
T - 30min easy spin + weights
W - 3.3@9:03 on flat dirt/grass
Th - 30 min spin (AM)
4.7@8:28 on road with hills (PM)
F - weights
S - 9@8:24 on hilly dirt road
S - 5k race in 36:01 (11:36 avg) pacing my boy
23.4M // 3h30 of running // 9:00 avg + 60min spinning and 2 weight sessions
M - 3 easy
T - Off
W - 5 Hilly
Th - 4 easy
F - 2 Tempo
Sa - Off
Su - 10 Long
24 miles total.
I put in less miles this week because instead of today's long run, I ran a little 5k with big dog that was put on and for a local rescue group. The race was pretty low key and I am sure we were pretty slow (did not bother with a watch or Garmin), as it weaved along these little paths around a park that is only about 1.2 miles around, so we had lots of twists and turns, as well as rolling hills. The timing was old school so they are still working through the numbers, but I do know I was the second female (so clearly a VERY uncompetitive race), my girl was the 3rd dog (1st dog with a female runner) and we had a lot of fun with all the other doggies. Other than that I spent a lot of time on the trails this week and although several of my runs were only 5 mile shorties, due to the elevation gain of around 1,200 feet on those routes, the time on feet was comparable to 7ish mile road runs and a tougher effort than an easy 7 mile road run. Next week will be one of adjustment as tomorrow I begin Nursing school and the long exhausting days that come with that endeavor. It will probably take me a few weeks to figure out when I can realistically get my running in and in 6 weeks things will get tougher with back-to-back 12 hour clinical days on top of classroom days and homework/studying, so more adjusting will be necessary.
Mon - AM: 5 mile Trail run inc. 1,200 ft gain w/Big Dog; PM: 30 min. core work
Tue - AM: 5 mile Trail run inc. 1,200 ft gain w/Big Dog; PM: Easy 3 mile run on crushed gravel paths w/little dog
Wed - Medium 10 mile trail run inc. 1,400 feet gain
Thu - AM: Easy 6 inc. 4 w/big dog and 2 joined by/Mike and little dog; PM: 60 min. BodyPump Class
Fri - 7 inc. 5x15 sec. strides w/Big Dog; PM: 30 min. core work
Sat - AM: 5 mile Trail run inc. 1,200 ft gain w/Big Dog; PM: Easy 2 mile w/Little Dog
Sun - 5 miles inc. 2 mi. w/u + 5k race (too busy chatting it up to go do a c/d)
Total Miles: 48; Other: 1x60 min. BodyPump, 2x30 min. core work
Su: off, still feeling my steeple workout
M: 5 easy, see above
Tu: 4x800m @ 5,000m pace w/2min rec, super easy, just cruising pace work
W: 7.5 easy
Th: 6x400m @ 1,500m pace w/1min rec, pretty comfortable. pm: 4 easy
F: 4 easy
Sa: JC state meet, blah. windy as hell, ran bleh. o well
total: 39.5 w/ blah race. o well, can't win em all!
Mon - road bike ride for 25 miles
Tues - 6.8 mile run
Wed - road bike ride for 25 miles
Fri - road bike ride for 25 miles
Sun - Morgan Hill Sprint Triathlon (3/4 mile swim, 16 mile bike, 5 mile run).
My first Tri. My swim and transitions need a lot of work, but I had a very good bike leg and one of the fastest run times at the event (ran 5 miles in 31 minutes after coming off the bike). Overall, really pleased with today. Now I'm motivated for the Vineman 70.3 triathlon in July.
BTW, the triathlons are a summer diversion and cross training for me. After July I start training for the Long Beach Marathon.
W - power yoga
Th - 5.35 @ 8:16
Sa - 4.02 @ 9:16, paced by DS on his bike
Su - 4-mile RT walk with DS on his skateboard to/from a birthday party. Then, waited for DH to come home from Mammoth so I could run long. Did 10 @ 8:33, powered up the hills!
total - 34.46
Good luck with Day 1 of Nursing school Radi...and of course all that follows!
M: 6m
T: 6m
W: 6m
Th: rest
F: 5m
S: 4m
Sun: 12m
Total = 39 miles
I never put my paces in because I am too lazy. I did get more than the usual in terms of tempo...that was nice. I need to get more core work in...only did 2 days. I'm gonna get flabby if I don't step it up.
Mon - 9.00
Tue - 11.10 (including 6 x 1 miles @ 7:29/mile, final tempo run, Week 17 Hanson's)
Wed - 2.00
Thu - 15.60 miles (including 10.00 miles @ 7:36/mile, final strength run, Week 17 Hanson's)
Fri - 11.70 miles
Sat - 5.40 miles
Sun - 13.75 miles (including 8.00 miles @ 7:38/mile, faster than I should have gone and this needs to be my last harder effort run leading up to M2B Marathon next Sunday...started with an 8:50 opening mile but then, as is typical for me, ran too hard for the remainder).
Total: 68.55 miles. I'm literally running twice as many miles coming into this year's Mountains To Beach Marathon as I was coming into last year's version of the race. I hope this allows me to shave 15 minutes off last year's 3:43 and I am down 7 or 8 pounds from where I was last year, as well, for this race.
Crosstraining is but a distant memory...just don't have the time and given that the earliest the classes start at my gym is 5pm on weekdays and that I am usually home by 5:30pm these days to give my DW a break with our baby, it doesn't look like I'll be doing much crosstraining anytime soon. But, I should start doing some things at home like pushups and planks but nothing before the San Francisco Marathon.
M: 8 easy
T: 3X3200 @10K; 14.6 total miles
W: 5.3 easy
Th: 7.2 easy at lunch, 3 easy PM
F: 9.4 easy, with some pickups
S: 4 miles tempo with 8 miles warmup and 3 cooldown
Sun: 3 miles easy
Total = 65 miles
I'm feeling super fit. That tempo on Saturday, while only at 6:40 pace, felt downright easy.
Rocky - dont' feel bad about losing the crosstraining, if you're goal is to run fast. Double the miles and 7 or 8 pounds down from what you were/did last year = huge positive for M2B.
M: 5.1 recovery (8:09/mi)
T: 7 slow (8:00)
W: 10 easy (7:44) w/slight progression last 3 miles
Th: 5.1 recovery (8:13)
F: 8.1 slow (7:55)
Sa: 5 slow (8:00)
Su: 15, progression (7:03, last 5 at 6:35)
Total: 55 miles
This was a mileage increase from the last few weeks so I just kept things slow and easy for the most part, focusing on making sure I'm getting adequate recovery. I'm still not totally 'in control' of the 15-milers -- while I can do a little workout, it's by no means easy to generate pace late in the run.
M: 4.51 miles (9:26 pace)
T: abs/ arms weights class and 3 miles treadmill (10:00 pace)
W: 11.3 miles (9:17 pace)
Th: SRD
F: 7 miles (9:09 pace)
Sa: SRD
Su: 9.23 miles running and about 10 miles walking
including Bay to Breakers 12K in 57:41 (7:45)
14th AG F 40-49/2169, 21st master F/4371, 140th F/ 11068, 851st OA/21284,
garmin 7.61 miles (7:35). Splits: 6:56, 7:28, 8:37 (Hayes hill), 7:54, 7:29, 7:36, 7:24, 6:56.
slight negative split, though too warm for me and Hayes St ate me up.
Started as a seeded athlete for the first time, which was pretty cool (though I felt a bit out of place), getting to see the elites warming up and starting with the speedy folks and the fast centipedes (stayed with the 2nd place female centipede for half a mile, but figured maintaining a 6:30 pace would not behoove me)!
total: 35.04 miles
Struggled at the start of the week, but good closing and made my goal of a sub 1 hr B2B (and a 4 + minute PR in the process). Will work on hills a bit over the next couple weeks before SFM and work on mild mileage bump.


text:
And, of course, the fine print:
Get free shipping on your next order when you spend over $100. The discount will be automatically applied to your purchase; no promo code required. The subtotal of your purchase must be $100.01 or greater after any promotional discounts have been applied. Additional fees such as tax or shipping and handling do not apply toward your minimum subtotal requirement of $100.01. Offer applies to standard shipping only. Certain items that require additional shipping and handling are excluded from this promotion and do not apply towards your $100.01 subtotal minimum. Offer subject to change.
Say sayonara (or goodbye, if you prefer) to the sticky, brittle toffee of yesteryear. This stuff is the real deal — crunchy and fresh, only made with real butter, sugar, milk chocolate and hand-sliced almonds. Every batch of chocolate toffee is made by hand — no assembly lines, machines or microwaves. Just people and toffee.
- Packaged in a mason jar
- Measures 20 oz.
- Real butter, sugar, chocolate and hand-sliced almonds
- Made in Michigan by hand
This product ships from the maker within 5 days, via FedEx
** This item may have additional shipping charges applied at checkout.
Unused and unopened items may be returned within 14 days


text:
Monsters University, Lone Ranger, ED-209, Disney/Pixar Planes, More!...
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text:
Mango Salad with Hearts of Palm, Radishes, Lime, and Cilantro
(Makes about 4 servings, recipe adapted from papaya salad recipes from Martha Stewart's Great Food Fast and Simply Delicioso. Mangos used to test this recipe were provided by the National Mango Board.)
1 mango
1 can hearts of palm (I used a 14 oz. can)
6-8 large radishes and cut in half-moon slices
2 green onions, sliced
1/2 cup chopped cilantro
Dressing Ingredients:
1/4 cup fresh lime juice
2 tsp. Dijon mustard
1/2 tsp. Spike Seasoning (optional but recommended)
2 T olive oil
South Beach Diet and Low-Glycemic Suggestions:
More Delicious Ways to Use Hearts of Palm:
(Recipes from other blogs may not always be South Beach Diet friendly, check ingredients.)
Hearts of Palm Salad from the Silver Spoon
Tomatoes, Hearts of Palm, Olives, and Feta with Basil Vinaigrette
Green Bean Salad with Hearts of Palm, Olives, Red Pepper, and Feta
Arugula Salad with Hearts of Palm, Kalamata Olives, and Gorgonzola
Rice with Palm Hearts from Morsels and Musings
Heart of Palm Risotto from Technicolor Kitchen
Italian Tuna and Pasta Salad with Hearts of Palm from La Mia Cusina
Hearts of Palm Salad with Artichoke Hearts and Vegan Ceviche from Where's the Revolution
Heart of Palm Parmesan Salad from Tico Food
Heart of Palm Amuse Bouche from The Skinny Gourmet
Want even more recipes?
I find these recipes from other blogs using Food Blog Search.


text:
so i was at a tourn last weekend and i was talking with the guys in my group about soft putters. well one of the guys had one of the original proto soft avairs. it was the super soft plasticbut the rim was stiff. it felt great in the hand and the couple of times i threw it.
is there a super soft putter out there that has a stiff rim but its still floppy?


text:
Maybe we can share our favorite guided meditations here for others to enjoy?
Here are my favorites:
Ajahn Brahm's guided meditations: http://www.youtube.com/user/DhammalokaMeditation
His metta meditations are especially good!
Here's one of them: http://www.youtube.com/watch?v=Evx5X8g7prM
I also like Tara Brach's guided meditations. This one is a Vipassana meditation with peaceful background sounds: http://www.youtube.com/watch?v=XHhDCW4Q1Rc
With metta!


text:
Hanging Temple Bells
This item is currently not available.
Additional Information
Temple Bells Ring in the Holidays
- Rustic bells announce the arrival of visitors
- Great for the holidays or year-round
- Metal bells with wooden clackers create a pleasing sound
Like those found in Himalayan temples, these rustic golden bells have wooden clackers that create a pleasantly deep, soulful resonance. Hang them on a door or covered porch. Jute rope with three painted steel bells.
Product Details
- Painted steel, wood, jute
- 24-1/2" L overall
- Three 4-1/2" H bells
REVIEW SNAPSHOT®by PowerReviews
Best Uses
- Was this a gift?:
- No (4)
Reviewed by 10 customers
- Even In High Wind Area
Best Uses
- None Without Sound
Purchased this item to have some chimes in my garden. We live in a windy area and nothing makes this temple set of bells ring. It was on sale but not worth anything to me just hanging there.
- Was this a gift?:
- No
- Hang Them On A Gate
Best Uses
- Garden Doorbell
These simple bells are beautiful and durable. They have a wonderful sound. I enjoy them every time my gate is opened.
- Was this a gift?:
- No
- Not Well Made
Best Uses
They do not make much noise and they seem to be cheaply made. Not what I expected.
- Was this a gift?:
- No
Should have believed the other reviews on this product. The bells barely make any sound and I would rate the quality as poor.
- Was this a gift?:
- No
- Pretty sound
- Rustic look
- none
Best Uses
- Gate
Got these for my mom for Mother's Day, so I haven't given them to her yet, but I think she will love them. We have a backyard gate to the driveway, which I bought these purposely for. I think she will love them and they will be perfect for the gate, so she can hear someone coming from the patio. Excited to give them to her on Sunday!!!
- Was this a gift?:
- Yes
These bells are lovely and sound really nice, but I expected them to be louder. In order to use them as gate bells as intended, we will have to modify them to make them noisier.
- Easy to hang
- Lovely sound
- Need To Replace Hanger
Best Uses
- Door decoration
The bells look great hanging on the front door with a Christmas wreath. The jute hanger wore through where it attached to the door hanger - too much movement due to wind(?) I've had many compliments on how the bells look and sound.
- Beautiful sound
- none
Best Uses
Hanging on door knob lets you know when someone is coming in or leaving; nice joyous sound.
I just received these bells yesterday and they are nice. But they do need a little holly around them or some other holiday decorations to make them festive though. I have them hanging from a closet door handle with garland and lights hanging over the arch of the door. They are large enough to notice them and they add alittle something extra, the matte gold finish on them is pretty. The bells don't make a whole lot of sound though...almost like a small cow bell would make. Overall happy with the purchase, although a little pricey, I know I will have them forever and can leave them up year round.
One bell does not have a clapper, and the clapper is wood, so the bell "noise" sounds like a cow bell, but not in a good way. I know I have seen similar online, though of course, I cannot find them now. Sending back.


text:
SCOTTSDALE, Ariz. -- Francisco Peguero was standing at his locker a few minutes before the Giants' NLDS roster was announced last fall when Aubrey Huff approached.
"Pegs," Huff asked, "Do you know if you made it?"
The math was simple: If Peguero was on the roster, it was to serve as a pinch-runner for Huff, who ultimately made all three postseason rosters anyway. Peguero did not, but he was allowed to stick around as an insurance policy, and he's now reaping the benefits of that extra month of big league work.
Peguero went 2 for 4 on Tuesday in a 4-3 loss to the Cleveland Indians and saw his spring average drop 13 points to .550.
"It helped me a lot," Peguero said through interpreter Erwin Higueros, when asked about last season's big league cameo. "I feel ready. I think I'm playing very well and making a good impression."
Peguero certainly has made an impression on manager Bruce Bochy, who is looking for a fifth outfielder. In a crowded field that includes Cole Gillespie, Roger Kieschnick, Juan Perez, Gary Brown and possibly even Brett Pill, Peguero has been an early standout. He has 11 hits in 21 at-bats, along with six RBIs and four runs.
"It's going to be a tough decision, but he's doing what he needs to do," Bochy said.
Peguero, 24, was signed out of the Dominican Republic in 2005 and has displayed a rocket arm, speed and the ability to hit for average and power while steadily climbing through the minors. He has a .305 average in seven minor league seasons, and a year ago at Triple-A Fresno, he hit .272 with five homers, 10 triples and 20 doubles.
Peguero stole 40 bases in 2010 but has had two knee surgeries, the second of which slowed him last spring. He showed Tuesday that the knee is now healthy, nearly legging out an infield single on a routine grounder to third.
"Last year I didn't get a chance because of my knee," he said. "This year is completely different because I'm playing more and getting more opportunities. That's what you play for, to make a case for yourself."
With every hit, that case is getting stronger.
Those are small details, things that can be taken care of in March.
In the offseason, Bumgarner had a bigger concern. He called his fellow starters, all of them veterans, and asked how they were preparing for 2013 after a long 2012 run.
Bumgarner, who threw 2231/3 total innings last season, ultimately chose a routine that fell somewhere between Tim Lincecum's "only on flat ground" throwing program and the heavy mound work done by Ryan Vogelsong and Barry Zito. Until he got to Scottsdale, Bumgarner played only long toss, but he arrived in camp early and threw off bullpen mounds.
"I took it a little easier this year," Bumgarner said.
That has resulted in a little rustiness. Bumgarner has given up eight hits and four walks in his first 52/3 spring innings, but he wasn't concerned after Tuesday's outing, in which he gave up a run on three hits with a walk and three strikeouts in two innings.
"Maybe if I'm doing this with a week to go, I might feel concerned," he said. "Right now I feel good. The command will come."
"I'm getting a lot of confidence, and I'm finding the right combination of mechanics," he said.
Brandon Crawford also hit a home run, and Gillespie had two hits. Brett Bochy pitched a scoreless inning out of the bullpen.
Tim Lincecum (blister) played catch and remains on schedule to start Thursday.
For more on the Giants, see Alex Pavlovic's Giants Extra blog at blogs.mercurynews.com/Giants. Follow him on Twitter at twitter.com/AlexPavlovic.


text:
Halloween Bat with Houndstooth Pattern Print-to-the-Edge Round Labels , 9 per sheet
Avery Pre-Designed Templates Microsoft Word
Set the scene for some happy haunting with these round labels. Great for candy bars, party favor bags and more. Look for matching postcards, labels, tent cards and tags.
Compatible Products:
22830, 41462, 41493, 22926, 22963, 22856


text:
Christina Aguilera isn't the only star playing Santa to Britney Spears' babies. Paris Hilton is bestowing her style prowess on little Sean Preston and Jayden James. Now before you gasp thinking of Brit's boys wearing Cavalli minis, blinged-out tiaras, and clutching Chanel bags, rest assured that Paris actually picked up cute, sensible gifts at Kitson Kids. For Jayden, Paris snagged a No Added Sugar Mummies New Man Onesie, $48, and adorable bibs, like this Available for a Playdate, $18. Sean Preston scored a Great China Wall Los Angeles Car Hoodie for $195. And of course, they'd be equally adorable for the pint-size popsters in your life, as well!
For more great gift ideas, click here for PEOPLE's Ultimate Gift Guide, and click here for more perfect presents in Off the Rack.
Photo: shopkitson.com


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Owen Barfield World Wide Website
Owen Barfield Press Books on Amazon FOBs: Friends of Barfield [a roster of Barfieldians] Barfield Resources [a variety of Barfield materials: bibliographies, weblinks, photos, Towards, etc.] Definitive Bibliography of the Published Writings of Owen Barfield [by Jane Hipolito] Barfield Timeline [the major events of Barfield's life in the chronological context of his era] Encyclopedia Barfieldiana [a hyperlinked, comprehensive Barfield reference work: key terms, ideas, influences, & themes] Barfield Scholarship [a sampling of essays and book chapters on Owen Barfield & his work]
Now available as an Amazon Kindle Book
Watch Owen Barfield Man and Meaning on Vimeo Owen Barfield Society
Created and maintained by David Lavery, Professor of English and Popular Culture, Middle Tennessee State University. Please report any broken links or problems with the site to him at email@example.com. All images on this site are believed to be in the public domain. Anyone wishing to challenge that assumption should contact the webmaster.


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The Mind of Marc Ecko
Posted 21 June 2007 - 07:43 AM
Posted 21 June 2007 - 01:20 PM
2000+ views of this thread.. daamn
It's a damn good thread
Posted 21 June 2007 - 02:21 PM
It's a damn good thread
I think it's what many people are craving for. Instead of regular tutorials that may teach you one gag, this shows many aspects of a real project with creative solutions. If more people would post a few of their inner workings of projects, we would all be in heaven (if I believed in such a place). It's like the mograph equivelent to director's commentaries on DVDs.
Posted 21 June 2007 - 05:16 PM
Posted 22 June 2007 - 12:02 AM
nice review thanks for the insight. I think the material you may be looking for in mental ray for maya to make the hourglass more clear and bright is the dielectric. i nearly got the results of the c4d render right out of the can without too much adjusting. I did bump the ambient to super white, but other than that its fairly close. however i always think its cleaver when you can use more than one 3D app to really exploit the strengths of each package. nice work!
i posted the picture of the maya hourglass i worked up here.
Thanks for the input.... but the problem wasn't actually getting the glass to look pretty, the problem was getting the watch to look pretty BEHIND the glass. The dialectric material is a wonderful tool i agree, but lighting the watch through the glass was a real pain. Nothing i did to counteract the problem looked as good as the watch did without the glass. So, as time constraints grew near, i just rendered the watches without the glass and then camera mapped the renders back onto the model. A simple but effective trick that ended up saving a lot of time.
Posted 31 July 2007 - 08:03 AM
Posted 01 August 2007 - 07:29 PM
#48 Guest_spence_*
Posted 02 August 2007 - 09:17 PM
Posted 02 August 2007 - 10:46 PM
You will find many threads on mograph describing people's preferences regarding Maya/C4D. Most of those arguments come down to Maya looking a little bit better and C4D being a bit faster and more flexible. It's an empty argument that is largely dependent on the experience of the user. There is little to no advantage of using two different programs... this piece could have been done in either. I mentioned earlier that Drizzle only knows Maya and I only know C4D. We've been working with each other for a few years, but this is the first time we "successfully" blended the two programs.
What is the distinction in the workflow between Maya and C4D? Why use both programs instead of one or the other? And what is done with each program?
The piece definately has it's weak spots. I did mention earlier (I think) that the city scene was slated to get more detail and resolution, but time didn't permit. I felt the camera was pretty good and transition was smooth, which I think is what most people were responding to. I would always pick that combo over a really sweet render that lacked action (and in the non-real world I'd prefer plenty of time and money to make it all happen).
The shifting wallpaper textures are damn sexy, but I have to say I'm surprised the city/gears part is most people's favorites though, I found the city to be kind of out of place compared to how tight everything else was.
The illustrator who developed the wallpaper stills is Dan Funderburgh and he is a cream o' the crop wallpaper designer (among many things he earns a living designing real & virtual wallpapers). Dan's been a very close friend for over 10 years, but this was the first time we actually worked together. It was a real treat.
#50 Guest_spence_*
Posted 03 August 2007 - 12:26 AM
The illustrator who developed the wallpaper stills is Dan Funderburgh and he is a cream o' the crop wallpaper designer (among many things he earns a living designing real & virtual wallpapers). Dan's been a very close friend for over 10 years, but this was the first time we actually worked together. It was a real treat.
Sorry to hijack another thread, but those wallpapers are gorgeous, I'm going to have to pick one of those up in hopes that some day I'll have my own place to put them up in
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Identity federation sample application for an Active Directory use case
This sample is intended for developers who want to learn how to use the identity federation capabilities of AWS Identity and Access Management (IAM). It illustrates how to issue temporary security credentials for accessing Amazon S3 files/buckets, using permissions that are tied to an Active Directory user.
(Please refer to the Readme.html file included within the documentation of this package for detailed setup instructions.)
To be able to run the sample code you need the following:
- Administrative access to an IIS server that is joined to an Active Directory domain. We have tested the application using Microsoft IIS version 7.5.
- A computer which is joined to the same Active Directory domain.
- A domain user account which can be used to run the command line interface (CLI) part of this sample application.
- A copy of the latest version of AWS SDK for .NET
- You must be signed up for Amazon S3 and have access to an Amazon S3 bucket with at least one file in it.
- Windows Communication Foundation should be registered on the running the IIS server. You can refer to MSDN to ensure this.
What does this sample do?
The sample package includes the following components:
This is a Microsoft Internet Information Services (IIS) hosted server-side application that issues temporary security credentials for accessing AWS APIs. The application administrator can configure permissions to control which Amazon S3 resources an Active Directory user can access, using fine-grained rules. The web service implements a GetToken interface that is called from the SampleConsoleApp/CLI. The sample implementation performs the following illustrative steps:
- It determines the Windows user name from the web request.
- It retrieves the AWS credentials (AWSAccesskey, AWSSecretkey) from the Web.config to authenticate itself.
It retrieves the Access Policy for the authenticated user from the user-to-policy mappings stored in the Web.config file.
- It requests temporary security credentials by calling the AWS API GetFederationTokenRequest with a valid name (in our example of the form user@domain),
an expiration time set to 8 hours and the policy retrieved in step 3.
# Code snippet GetFederationTokenRequest request = new GetFederationTokenRequest { DurationSeconds = 3600 * 8, Name = awsUsername Policy = policy };
- The temporary security credential is returned as a JSON-serialized response which contains:
- AccessKeyID - the access key identifier for the temporary credentials.
- SecretAccessKey - the key used to sign requests.
- SessionToken - the security token.
# Code snippet GetFederationTokenResponse startSessionResponse = null; startSessionResponse.client.GetFederationToken(request); // Check the result returned i.e. Valid security credentials or null? if(startSessionResponse!= null) { GetFederationTokenResult startSessionResult = startSessionResponse.GetFederationTokenResult; sessionCredentials = startSessionResult.Credentials // Store all the returned keys and token to TemporarySecurityCreds temporaryCreds.AccessKeyId = sessionCredentials.AccessKeyId temporaryCreds.SecretAccessKey = sessionCredentials.SecretAccessKey temporaryCreds.Expiration = sessionCredentials.Expiration temporaryCreds.Token = sessionCredentials.SessionToken }
This is a CLI to be run by an Active Directory user. It interacts with the SampleFederationProxy to obtain temporary security credentials and uses them to access an Amazon S3 bucket. The sample implementation performs the following illustrative steps:
- It posts a web request to the GetToken service provided by the SampleFederationProxy.
- It uses Integrated Windows Authentication to enable the web proxy to authenticate and authorize the caller.
- The SampleFederationProxy responds with a valid temporary security credential.
These credentials are used to access Amazon S3 files/buckets.
# Code Snippet # Listing Amazon S3 bucket content using the returned temporary redentials
// Add credentials to create a S3 client SessionAWSCredentials sessionCredentials = new SessionAWSCredentials( temporaryCreds.AccessKeyId, temporaryCreds.SecretAccessKey, temporaryCreds.Token); s3Client = new AmazonS3Client(sessionCredentials); ListObjectsRequest request = new ListObjectsRequest(); request.BucketName = bucketName; ListObjectsResponse s3Response = s3Client.ListObjects(request);
Seeing the application in action
Login as the domain user to the computer that is joined to your Active Directory domain and run the SampleConsoleApp CLI.
Once the security credentials are successfully received, you can use the simple menu provided by the SampleConsoleApp to access Amazon S3 files/buckets.


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SAN FRANCISCO Gap Inc. announced that it is opening a pop-up store for its Piperlime brand. The online-only brand will occupy its first brick-and-mortar space on Mercer Street in Manhattan's SoHo neighborhood. The pop-up store will be open for 25 days, starting September 9 to align with New York Fashion Week and closing on Oct. 3, the company reported.
The pop-up store will include an edited assortment of the top fall styles from coveted brands like Marc by Marc Jacobs and Frye, tips on how to wear the season's trends, favorite picks from fashion editor and stylist Rachel Zoe and exclusive product from brands such as 7 For All Mankind, AG Adriano Goldschmied, Cynthia Vincent and more, Gap reported.
"We are excited to share this experience with the public," said Jennifer Gosselin, general manager of Piperlime. "It's the first time that Piperlime will be available in a three-dimensional environment, where customers can touch and feel product, put together head-to-toe outfits, and pick personal favorites from exclusive jewelry items to vintage-inspired tops to the must-have-boot for fall."
Piperlime will also introduce the "styling loft" within the store, a designated area where customers can show their own creative style. Piperlime will reveal a daily creative brief and customers will have the opportunity to style outfits that meet the challenge and submit their looks for a chance to be showcased in the store and win a Piperlime Giftcard.


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PINKALICIOUS, THE MUSICAL Will Play NJ, PA, OH Before Arriving at the Riverside Theater in February
Vital Theatre Company has announced that its long-running production of Pinkalicious, The Musical will play its final performance at the Culture Project (formerly Bleecker St Theatre) on Sunday, November 11th at noon. The production will continue performances at the new Hamilton Stage for the Performing Arts in Rahway, New Jersey on November 17th at 1 pm and November 18th at 11 am, then will appear on tour in South Orange, NJ; Easton, PA; Lakewood, NJ; Red Bank, NJ; Sandusky, OH; and New Albany, OH before it will return to its new home at the Riverside Theatre in February of 2013.
Remaining performances of Pinkalicious, The Musical at the Culture Project are Saturday, November 10th at 1:30 pm and Sunday, November 11th at 12 noon. Tickets for the remainder of the run are now on sale. Tickets are $29.50 for regular seats and $49.50 for premium seats. They can be purchased by visiting www.pinkaliciousthemusical.com, by calling (212) 579-0528, or by visiting the Culture Project box office one hour before the performance begins. The Culture Project is located at 45 Bleecker St, between Lafayette Ave and Mott St.
Pinkalicious, The Musical, one of Vital Theatre Company's longest running shows, was originally commissioned and developed by the company in 2006, making its debut at the McGinn/Cazale Theatre at 76th and Broadway that year. Since completing its initial sold-out six week run, it has played across the city, at venues including the Soho Playhouse, New World Stages, MMAC (Manhattan Movement & Arts Center), and the Bleecker Street Theater (now Culture Project). It has been touring across the US and Canada for over four years; touring continues this year with performances in New Jersey, Pennsylvania, Ohio, Arkansas, Mississippi, Texas, Virginia, and Delaware.
In Pinkalicious, The Musical, Pinkalicious can't stop eating pink cupcakes despite warnings from her parents. Her pink indulgence lands her at the doctor's office with Pinkititis, an affliction that turns her pink from head to toe - a dream come true for this pink loving enthusiast. But when her hue goes too far, only Pinkalicious can figure out a way to get out of this predicament.
The one hour musical, with book and lyrics by Elizabeth Kann and Victoria Kann and music, lyrics and orchestrations by John Gregor, is based on the popular children's book Pinkalicious by Elizabeth Kann and Victoria Kann. The musical adaptation is directed by Teresa K. Pond with choreography by Dax Valdes and musical direction by Jad Bernardo with original direction by Suzu McConnell-Wood.
John Gregor (Music, Lyrics & Orchestrations) received a 2004 Frederick Loewe Award for his musical WITH GLEE, for which he wrote the book, music and lyrics. WITH GLEE was presented in a workshop by the Skirball Center for the Performing Arts, NYU, and premiered at the New York Musical Theatre Festival last summer. Last summer, WITH GLEE enjoyed an extended run with Prospect Theatre Company. His musical adaptation of Gogol's tragicomic short story THE OVERCOAT has been presented in London at the Bridewell Theatre, and at the Barrington Stage Company and The New York International Fringe Festival. He has also co-written several children's musicals for Vital Theatre Company, including THE CHANGELING and THE BULLY.
Elizabeth Kann & Victoria Kann (Book & Lyrics) are co-authors of the New York Times best-selling children's picture books PINKALICIOUS (HarperCollins, 2006) and PURPLICIOUS (HarperCollins, 2007) that Victoria also illustrated. Elizabeth and Victoria are sisters who grew up in Brooklyn, New York. Victoria's award-winning artwork has graced the covers and pages of many magazines, newspapers, and books. Elizabeth's writing has appeared in a variety of newspaper and print publications. To learn more about the sister duo and their books, visit them online at their website at www.thinkpinkalicious.com.
Teresa K. Pond (Director) has helmed premiere productions and readings with The Women's Project Theatre. New York credits include NYC Fringe Festival award-winning premiere HALF LIFE. Regional credits include MUCH ADO ABOUT NOTHING (Loft Theatre, NY), MACBETH, TARTUFFE (Studio Theatre, CA). THE CLEAN HOUSE, NICKEL AND DIMED (Western Stage, CA), THE FOREIGNER, PERFECT WEDDING (Millbrook Theatre, PA), SYLVIA and SHAKESPEARE IN HOLLYWOOD (Cyrano's Theatre, AK). Ms. Pond has also directed several operas, including: SUOR ANGELICA, PAGLIACCI (Anchorage Opera), BARBER OF SEVILLE (Bleecker Street Opera), AMAHL AND THE NIGHT VISITORS. She is a member of The Lincoln Center Directors' Lab, The Women's Project Directors Forum, and co-leader of the NYC playwright-director company NewShoe. Current Productions include: CAROLINE OR CHANGE (Cyrano's Theatre, AK) and RICHARD III with New York Classical Theatre in Central Park. She is also proud member of Stage Directors and Choreographers Society (SDC).
Since 1996, Culture Project has told stories as timely as the morning's newspaper in a way that cannot be matched by commercial media. Through brilliantly conceived, expertly staged dramas, which blend prize-winning theater with urgent moral dilemmas, Culture Project sparks conversation and incites political action. A venue for acclaimed, prize-winning performance, Culture Project is also a magnet for today's best talent including Meryl Streep, Danny Glover, Mary J. Blige, Robin Williams, Marisa Tomei, Bob Balaban, Rinde Eckhert, Montel Williams, Frank McCourt, Staceyann Chin, Lynn Redgrave, Sarah Silverman, and other artists who share a passion for theater and public justice.
The Riverside Theatre presents a diverse range of programming that includes cutting edge choreography in our dance festival, heart wrenching documentaries like Congo: Red Rubber, White King, Black Death and the enchanting theatrical Orisha Tales. Bring your entire family for the NY Family Arts Festival, let your kids explore their creativity and talents in our Youth Theatre or visit one of our exhibits. You will find as many as 120 annual performances of dance, music and drama to choose from. We want to engage, educate, and inspire you. Whether you want to attend original dance productions, film premieres, musicals, plays or volunteer as an usher, The Riverside Theatre welcomes you.


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This is just a quick question.
I can throw about 300-350 ft. I can throw with decent power. I can hyzer and anhyzer very well but the next shot I want to learn is the hyzer flip. The disc I want to flip is a beat in Avenger SS. But the question is how do I do it? I can hyzer with it but my question is do I pull back straight and throw as if I was throwing straghit but try to tilt the disc? or how do I do it?


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Forest Green boss Ady Pennock delighted to snap-up Bradford City defender Luke Oliver
11:06am Monday 3rd February 2014
By Ashley Loveridge
11:06am Monday 3rd February 2014
By Ashley Loveridge
FOREST Green boss Ady Pennock has finally completed the protracted signing of 6ft 7ins former Bradford City central defender Luke Oliver.
Reports suggested the giant defender had signed on transfer deadline day were unfounded despite manager Pennock and club secretary Michelle McDonald frantically trying to seal the deal.
However, the 29-year-old free agent, who left Phil Parkinson's Bradford City City by mutual consent last week after over 100 games for the League One club is now a Rovers man until the end of the season with a one-year option.
"We've been in contact with Luke for a while now and he just needed to speak to his partner and sort a few things out, but the deal is done and we're delighted to sign him," said Pennock.
"Luke is a good age and has played at this level and also gained promotion from League Two."
Oliver picked up Player-of-the-Year and Player's Player-of-the-Year awards for The Bantams in 2011-12; and played the first 15 league games during Bradford's promotion season in 2012-13, before being sidelined with an Achilles injury.
Despite a full preseason behind him, a fit Oliver has played only four times this season in a Bradford squad with strength in depth in the middle of defence.
Oliver began his career as an 18-year-old with Wycombe Wanderers in the old Second Division (now League One) and played four times for them (2002-04).
Between 2004-2006, Oliver featured more than 50 times for Woking in the Football Conference.
He also played alongside Forest Green Academy manager Scott Bartlett while on loan at Salisbury City. He also made 76 appearances for Stevenage Borough and was part of FA Trophy winning side in 2007.
A move back to the Football League with Wycombe in January 2009 saw the imposing centre-half help Wanderers secure a return to League One with automatic promotion.
He started the 2009-10 season as first choice centre-half at Adams Parks before a loan spell with Bradford in March saw him once again join up with Peter Taylor – who had managed Oliver at both Stevenage and Wycombe – which ended in a permanent move to Yorkshire in the summer of 2010. On 22 June 2012, Oliver signed a new two-year contract with the club after they earned promotion to League One.
Oliver played 119 times for Bradford, including four this season, and scored three goals in all.
© Copyright 2001-2017 Newsquest Media Group


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Nabil Foods was founded in 1945 and today is considered one of the most prominent names in the frozen food industry in Jordan and the region. The company produces more than 200 chicken, meat, and fish products, along with a line of ready-to-eat frozen meals and desserts.
Nabil also supplies a number of international fast-food chains with food products for their operations.Less...
Contact Information:
King Abdullah The Second Industrial Estate,
P.O.box 11512,


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In fact, barring a trade, the Colts have only one pick in the first two rounds – the No.24 overall pick – after dealing a second-rounder to Miami for Vontae Davis. People debated that move for weeks afterward. I'm calling it a success. Davis looked strong at the end.
At any rate, here are the areas of most need, ranked from biggest to smallest:Andrew Luck can't be sacked 41 times next season. Maybe he won't simply because of the change in offense Hamilton will bring. One of Hamilton's initial comments was how he would install some West Coast offense philosophy, with more high-percentage passes. Presumably, that's less time holding the ball, less time for Luck to be shellacked. Completion percentage moving up.
But the offensive line needs some work. The Colts were rarely healthy across the board and some pieces didn't seem to fit.
Anthony Castonzo was solid at left tackle. You can put Joe Reitz almost anywhere and he'll thrive. Samson Satele was so-so. Winston Justice was decent, but often banged up.
If the Colts look for an offensive lineman with that lone high pick, the possibilities include Oklahoma's Lane Johnson (although most expect him to go higher) and North Carolina's Jonathan Cooper.Davis is solid at corner. Antoine Bethea is getting older, but can still play at safety. Tom Zbikowski doesn't seem fast enough or consistent enough at safety to be a regular starter. Jerraud Powers is a free agent corner, but some question whether he fits the Colts' defensive changes.
If Colts general manager Ryan Grigson was to find an offensive lineman or two through free agency, etc., the Colts could opt for a defensive back with that first-round pick. They haven't traditionally found DBs high in the draft, other than Bob Sanders, but this could be the exception.
Studying various mock drafts and college player analysis, it seems like Dee Milliner of Alabama would be a steal if he drops that far in the draft. Other possibilities include Florida States' Xavier Rhodes and Washington's Desmond Trufant.
Some speculated the Colts could be interested in Ravens free agent safety Ed Reed, longtime friend and former teammate of Colts wide receiver Reggie Wayne. Reed still has some game in him, but is he a bit old for the Colts' monster-building? Probably.A lot rides on whether second-year player Josh Chapman returns to full strength. He missed the entire season after offseason knee surgery. In occasional interview settings with Chapman – which is about all we have to go on for now – he seems determined to grab that starting spot. I'm willing to give University of Alabama products the benefit of the doubt.
A couple mock drafts speculate the Colts using their first-round pick on Alabama's Jesse Williams or Georgia's John Jenkins, but I don't see them using that pick for this spot.The chances of Dwight Freeney returning to the Colts seem to be about 10 percent on a good day. He's older, expensive and not necessarily the right fit for the Colts 3-4 defense.
Some fans have talked about the Colts pursuing the Ravens' Paul Kruger, who had a breakout season. But how expensive would he be, and is one good season worth gambling on a big contract?
Jerry Hughes has had more than a few chances to shine. He made more plays than he ever has last season. But, since he was on the field more, he missed more plays, too. Not sold on Hughes.Wayne will be back after drinking from the Fountain of Youth and giving Luck a tutorial in quarterback-receiver rapport.
T.Y. Hilton should be better, and he showed flashes of brilliance along with a few first-year drops. Donnie Avery made some plays, but had his share of drops, too. The verdict remains out on LaVon Brazill. He's got the speed if he develops the hands.
Maybe there's a late-round wide receiver diamond in the rough Grigson and coach Chuck Pagano can uncover. Luck can't have too many receivers, and a quality taller receiver would be a nice asset.
The top priority for the offseason has to be protecting the Colts' biggest asset in Luck. Give him more time and he'll figure out how to make the most of it.


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There's hope that an important set of 18th century railings from a legendary Mayfair mansion will stay in the UK, now that a serious buyer has come forward.
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There's hope that an important set of 18th century railings from a legendary Mayfair mansion will stay in the UK, now that a serious buyer has come forward.
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Uncoordinated movement is due to a muscle control problem that causes an inability to coordinate movements. It leads to a jerky, unsteady, to-and-fro motion of the middle of the body (trunk) and an unsteady gait (walking style). It can also affect the limbs.
The medical name of this condition is ataxia.
Lack of coordination; Loss of coordination; Coordination impairment; Ataxia; Clumsiness; Uncoordinated movement
Smooth graceful movement requires a balance between different muscle groups. A part of the brain called the cerebellum manages this balance.
Diseases that damage the cerebellum, spinal cord, or peripheral nerves can interfere with normal muscle movement. The result is large, jerky, uncoordinated movements.
Brain injuries or diseases that can cause uncoordinated movements include:
Poisoning or toxic effects caused by:
Other causes include:
A home safety evaluation by a physical therapist may be helpful.
Take steps to make it easier and safer to move around at home. For example, get rid of clutter, leave wide walkways, and remove throw rugs or other objects that might cause slipping or falling.
People with this condition should be encouraged to take part in normal activities. Family members need to be patient with a person who has poor coordination. Take time to show the person ways to do tasks more easily. Take advantage of the person's strengths while avoiding his or her weaknesses.
Ask the health care provider whether walking aids, such as a cane or walker, would be helpful.
Call your health care provider if:
In an emergency, the patient will first be stabilized so that symptoms do not get worse.
The health care provider will perform a physical exam, which may include:
Medical history questions may include:
Tests that may be ordered include:
You may need to be referred to a specialist for diagnosis and treatment. If a specific problem is causing the ataxia, the problem will be treated. For example, if a medicine is causing coordination problems, the medicine may be changed or stopped. Other causes may not be treatable. The health care provider can tell you more.
Lang AE. Other movement disorders. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 410.
Subramony SH. Ataxic disorders and cerebellar disorders. In: Daroff RB, Fenichel GM, Jankovic J, Mazziotta JC, eds. Bradley's Neurology in Clinical Practice. 6th ed. Philadelphia, PA: Elsevier Saunders; 2012:chap 22.
A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows rigorous standards of quality and accountability. A.D.A.M. is among the first to achieve this important distinction for online health information and services. Learn more about A.D.A.M.'s editorial policy, editorial process and privacy policy. A.D.A.M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health on the Net Foundation (www.hon.ch)
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- 2013 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.


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CoverGirl Outlast Double LipShine Reviews
Not Worth ItI keep trying long lasting lip products, but none of them seem to work. This is no exception. This product totally dried out my lips, did not apply evenly, and didn't smell good. It is not worth the money. — 6 years, 2 months agoTheLacqueredLady | 751 reviews
This review is: Helpful | Not helpful | Inappropriate | 2 of 2 people said helpful
Outlast, yes, but.....I really liked the color, Sheerly Nude, but it smelled funky. Even worse, the liquid gloss part was sticky like glue and greasy like heavy ointment. Then soon after I applied it, it became dry, and my lips looked like chapped. The staying power was great, but it just looked horrible on my lips, and when it was time to remove, it was hard to take it off. Now this lip gloss is tucked away inside a drawer for a long time. — 7 years, 10 months agoluckybetty | 895 reviews
This review is: Helpful | Not helpful | Inappropriate | 3 of 3 people said helpful
OkNot crazy about this product. Doesn't last very long, and the step 2 always looks messy. — 9 years, 7 months agosmiley48 | 204 reviews
bad buy!The texture of this is unpleasant. It left my lips dry and sticky at the same time. All in all, i did not like it and it wasnt worth buying. — 6 years agogaej19 | 147 reviews
Looks ridiculous after a few hoursThis lipstick looked fine when I first put it on (albeit too pink...I think most CG lipsticks are too pink). Anyway, after a couple hours, when the glossy topcoat started to wear off, I was left with clumps of color in the lines of my lips. If I smiled and you looked closely, you could see the tiny little stripes. The problem was exacerbated by the fact that the lipstick, despite the gloss, is sti...read morell kind of drying. I found the only way to fix the "stripe" problem was to put on a good lip conditioner and rub REALLY hard. I'd brefer a creamy lipstick that wears off quickly to an uncomfortable one that wears off unevenly. — 8 years, 8 months agoamygab1126 | 242 reviews
This review is: Helpful | Not helpful | Inappropriate | 5 of 5 people said helpful
Can't StandThe Lipstick part is feathery, grainy, fake-looking, too bright, pretty much everything you DON't want in a lipstick. However, the clear gloss was nice, when I tried it over another of my lipsticks. — 6 years, 6 months agoliliofthevalley | 34 reviews
Horrid.This was the first lip gloss I had ever used and I was extremely disappointed. I guess it added alright color to my lips and a lot of shine, but it felt heavy and sticky on my lips. I hated it. It later dried out my lips. I do not recommend this. — 6 years, 5 months agomkgx7 | 97 reviews
This review is: Helpful | Not helpful | Inappropriate | 2 of 2 people said helpful
amazingly the worst product i've tried yet.the clear gloss is not bad. the colored "lasting" portion is the worst outlast i have tried. Not only does it dry out your lips... It cracks within 20 minutes and no amount of perfect clear topcoat gloss can fix that! — 6 years, 9 months agoMrsBrunetteBeauty | 89 reviews
Stays long when applied correctlyThis is how I use this product, and it works wonderfully: 1. I exfoliate my lips with my toothbrush to remove any flaky skin. 2. I immediately apply vaseline to my lips to moisturize. 3. After a half hour, I wipe my lips of any remaining vaseline. 4. I apply the lip color by dabbing a little bit starting on the bottom lip. Blend before it dries. 5. Repeat on the top lip. 6. Wait for the produ...read morect to completely dry. 7. Apply the LipShine. 8. Do not let you lips dry out. Carry the LipShine with you and moisturize as needed. — 4 years, 1 month agomakeup_lover22 | 24 reviews
Bad!!!I hated this! It did not last & wore unevenly! A complete waste of money! — 5 years, 5 months agojola64 | 88 reviews
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My Reasons for Reporting This


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Dear Penthouse,
I never thought it would happen to me but… Actually, no, scratch that, like most men I always think it could and should happen to me all the time but I'm neither a plumber nor a pool maintenance man so my opportunities for random sexual encounters with hot frustrated house wives and sexy college lesbians with a taste for hairy male plumbers or the smell of chlorine are sort of minimal. But being a world-renowned chef there are compensations.
Why just the other day I was alone in the kitchen sipping lonesomely on a long cool glass of alkalised water with apple cider vinegar, thinking to myself, damn, this water tastes like crap. Who put all the effing vinegar in? Not even a banana and blueberry smoothie could wash the taste away. Especially after some jerk spiked it with a big ol' honking shot of spirulina which, believe me, tastes every bit as nasty as it sounds.
So anyway Penthouse, I always thought your letters were made up until this happened to me because really, in real life what sort of cultured vegetable gets a face full of spirulina without asking for it? But spitting out the nasty water and ruined smoothie I looked up and there they were… the almonds. Dark, sultry and almond shaped, just like the dark almond shaped eyes of a pair of sultry Penthouse style lesbians; you know, the ones who are totally into men.
Playing it cool I sidled up to them. Now wasn't the time to whip out a pair of pendulous emu meatballs. Now was a moment for quiet reflection, for style and sophistication. The sort of moment that might just lead on to a root. A liquorice root, of course. Bathed in warm water and poured all over a fiery mound of ginger.
"Well hello, my nutty little friend," I said. They were silent. Because almonds don't say much as a rule.
But they responded, oh how they responded, when soaked in a soaking balm of spirulina-free store-bought water. Would it be boastful of me to say, gentlemen, to say that by the time I was finished with them, those almonds were well and truly activated?
Why not join JB in the hottub at his personal blog? Cheeseburgergothic.com. He's got nuts.


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Your Man on the Ground
Dylan Eastman examines the original Blog Cabin 2013 foundation after the home is lifted.
Hi all and happy Friday!
Pretty soon, we will begin coverage of the Blog Cabin 2013 remodeling process. Starting the week of November 26, project manager Dylan Eastman will offer up regular reports from the home site and, in late 2012 or early 2013, we will launch our "Remodeling of Blog Cabin" package on HGTVRemodels.com. It will be packed with behind-the-scenes details: how we handled the home's many additions, made allowances for harsh coastal weather conditions and more.
So pull up a seat and plan to stick around — tons of photos and exclusive details are just around the corner!


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Jeannie and Jim Waltz of Union Presbyterian Church of Los Altos spearhead a project that involves filling shoeboxes with necessities for children in underprivileged countries for distribution via the nonprofit Samaritan's Purse.
Last year, they filled 60 shoeboxes, searching for items at post-Christmas sales and bargain hunting throughout the year at the Dollar Store, Target, Walmart and Michaels. The Waltzes and other volunteers have accumulated enough items to fill 102 shoeboxes this year.
The Waltzes have recruited fellow church members to help with the project – some have donated items and assembled boxes, while others have contributed funds to pay for the contents of the boxes and the mailing cost ($7 per box).
Boxes include items like toothpaste, toothbrushes, combs, brushes, washcloths, bars of soap, notebooks, crayons, pencils, colored pencils, pencil sharpeners, ballpoint pens, tissue paper, jump ropes, tennis balls, harmonicas, Slinkys, Lifesavers, T-shirts, socks, flip-flops, scarves, tote bags, baseball caps and bandannas.
To donate, mail checks to Union Presbyterian Church, 858 University Ave., Los Altos 94022. To drop off items, stop by the church office.
For more information, call 948-4361 or visit unionpc.org.


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Oregon SOS candidates spar over campaign finance restrictions
PORTLAND, Ore. (AP) - The Republican candidate for Oregon secretary of state is calling for voluntary restrictions on campaign spending in future years. But he's rejecting an offer by his opponent to impose them now.
Bend doctor Knute Buehler (NEWT BYOO'-lur) says it's too late to impose spending restrictions just weeks before the November election. He spoke Wednesday at a news conference proposing a variety of changes to the elections process.
Earlier Wednesday, Democratic incumbent Kate Brown pledged not to spend more than $1 million on her campaign.
Buehler says he wants to diminish the influence of money in politics. He said he wants candidates to voluntarily limit their campaign spending or give up their right to make a pitch in the voter pamphlet mailed with ballots before every election.
Copyright 2012 The Associated Press.


text: Expertise and rankings By Mayo Clinic Staff Print Multiple sclerosis research laboratory at Mayo Clinic Mayo Clinic's multiple sclerosis experts provide comprehensive care for nearly 3,000 adults and children with multiple sclerosis each year. Teamwork. With an emphasis on collaborative care, specialists interact very closely with their colleagues across all campuses. Mayo Clinic's MS program has earned a national reputation as a top diagnostic and treatment center. The program is recognized for its multidisciplinary approach to patient care as well as for its advanced research into improved medications and other treatments. The latest techniques and technology. At Mayo Clinic, researchers are always working to develop new treatments to improve outcomes for people with MS. For example, Mayo Clinic was one of the first clinics to treat MS with interferons. Mayo Clinic also developed plasma exchange and has been successfully using this treatment for more than 20 years. Research. Mayo Clinic experts continually study new diagnostic and treatment options, which they test through clinical trials. Mayo Clinic researchers were the first to discover that a certain type of T cell (CD8) plays a critical role in causing nerve damage in MS. This discovery may lead to new drugs to slow or stop that nerve damage. Learn more about this research at the Mayo Clinic Multiple Sclerosis Laboratory and the Center for Multiple Sclerosis and CNS Demyelinating Diseases. Nationally recognized expertise. The Pediatric Multiple Sclerosis Center at Mayo Clinic in Rochester, Minnesota, is recognized as a Pediatric MS Center of Excellence by the National Multiple Sclerosis Society. Mayo Clinic in Rochester, Minn., ranks No. 1 for neurology and neurosurgery in the U.S. News & World Report Best Hospitals rankings. Mayo Clinic in Phoenix/Scottsdale, Ariz., and Mayo Clinic in Jacksonville, Fla., are ranked among the Best Hospitals for neurology and neurosurgery by U.S. News & World Report. Mayo Clinic also ranks among the Best Children's Hospitals for neurology and neurosurgery. Learn more about Mayo Clinic's neurosurgery and neurology departments' expertise and rankings. Request an Appointment at Mayo Clinic Departments & specialtiesLocations, travel & lodging Aug. 04, 2017 Print Share on: FacebookTwitter References AskMayoExpert. What is multiple sclerosis? Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2014. Daroff RB, et al. Bradley's Neurology in Clinical Practice. 6th ed. Philadelphia, Pa.: Elsevier Saunders; 2012. https://www.clinicalkey.com. Accessed Dec. 16, 2014. Ferri FF. Ferri's Clinical Advisor 2014: 5 Books in 1. Philadelphia, Pa.: Mosby Elsevier; 2015. https://www.clinicalkey.com. Accessed April 4, 2014. Olek MJ. Epidemiology and clinical features of multiple sclerosis in adults. http://www.uptodate.com/home. Accessed April 4, 2014. Wingerchuk DM (expert opinion). Mayo Clinic, Phoenix/Scottsdale, Ariz. May 13, 2014. Kantarci O. Treatment of primary progressive multiple sclerosis. Seminars in Neurology. 2013;33:74. Keegan BM. Therapeutic decision making in a new drug era in multiple sclerosis. Seminars in Neurology. 2013;33:5. Goldman L, et al. Goldman's Cecil Medicine. 24th ed. Philadelphia, Pa.: Saunders Elsevier; 2012. http://www.clinicalkey.com. Accessed April 4, 2014. Lotze TE. Pathogenesis, clinical features, and diagnosis of pediatric multiple sclerosis. http://www.uptodate.com/home. Accessed April 5, 2014. Kantarci OH, et al. Novel immunomodulatory approaches for the management of multiple sclerosis. Clinical Pharmacology & Therapeutics. 2014;95:32. Olek MJ. Treatment of relapsing-remitting multiple sclerosis in adults. http://www.uptodate.com/home. Accessed Dec. 16, 2014. Olek MJ. Treatment of acute exacerbations of multiple sclerosis in adults. http://www.uptodate.com/home. Accessed April 4, 2014. Wingerchuk DM. Multiple sclerosis: Current and emerging disease-modifying therapies and treatment strategies. Mayo Clinic Proceedings. 2014;89:225. Pizzorno JE, et al. Textbook of Natural Medicine. 4th ed. St. Louis, Mo.: Churchill Livingstone Elsevier; 2013. https://www.clinicalkey.com. Accessed April 4, 2014. Olek MJ. Diagnosis of multiple sclerosis in adults. http://www.uptodate.com/home. Accessed Jan. 2, 2015. Polman, C, et al. Diagnostic Criteria for Multiple Sclerosis: 2010 Revisions to the McDonald Criteria. Annals of Neurology. 2011;69:292. http://onlinelibrary.wiley.com/doi/10.1002/ana.22366/pdf. Patient information: Multiple sclerosis. http://www.uptodate.com/home. Accessed Jan. 2, 2015. Olek MJ. Symptom management of multiple sclerosis in adults. http://www.uptodate.com/home. Accessed Jan. 2, 2015. Yadav Y, et al. Summary of evidence-based guideline: Complementary and alternative medicine in multiple sclerosis. Neurology. 2014;82:1083. Riggin EA. Decision Support System. Mayo Clinic, Rochester, Minn. Jan. 20, 2015. National MS Society. Network of Pediatric MS Centers. Accessed Feb. 10, 2015. http://www.nationalmssociety.org/What-is-MS/Who-Gets-MS/Pediatric-MS/Care-for-Pediatric-MS-%28Centers-of-Excellence%29. Rodriguez M. Plasmapheresis in acute episodes of fulminant CNS inflammatory demyelination. Neurology. 1993;43:1100. Deb C. CD8+ T cells cause disability and axon loss in a mouse model of multiple sclerosis. PLOS One. Aug. 30, 2010. FDA approves new drug to treat multiple sclerosis. FDA. Accessed March 29, 2017. RelatedDemyelinating disease: What can you do about it?Emerging treatments for multiple sclerosisExplaining multiple sclerosisLong-term safety of natalizumab for treating multiple sclerosis Vitamins for MS: Do supplements make a difference?Exercise and multiple sclerosisManaging depression in MSVitamin D and MS: Any connection?Stress management for MSCannabis for MS: Can it help treat symptoms?Mindfulness practice: Can it reduce symptoms of MS?Venoplasty treatment for multiple sclerosisManaging anxiety in MS: What works? Personalized therapy for multiple sclerosis (MS)Acetyl-L-carnitine: Can it relieve MS fatigue?Estriol as a potential treatment option for multiple sclerosis (MS)Multiple sclerosis: Can it cause seizures?Fingolimod during pregnancy: Is it safe?Inheritance patternsMedical marijuanaLumbar puncture (spinal tap)FatigueNumbness Mayo Clinic in Minnesota has been recognized as the best Neurology & Neurosurgery hospital in the nation for 2017-2018 by U.S. News & World Report. Learn more about this top honor Multiple sclerosisOverviewSymptoms & causesDiagnosis & treatmentDiagnosisTreatmentRequest an appointmentDepartments & specialtiesExpertise & rankingsLocations, travel & lodgingClinical trialsResearchCosts & insurancePreparing for your appointmentSelf-managementMore aboutIn-DepthExpert AnswersMultimediaResourcesNews from Mayo Clinic Diagnosis & treatmentRequest an appointmentDiagnosisTreatmentDepartments & specialtiesExpertise & rankingsLocations, travel & lodgingClinical trialsResearchCosts & insurancePreparing for your appointment CON-20130950 Patient Care & Health Information Diseases & Conditions Multiple sclerosis


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San Francisco, California
"The great aim of education is not knowledge, but action."
— Herbert Spencer
Jason Shaeffer began innovating, developing, and managing the production of online education and interactive media in 1999. He feels passionately that through online education we can democratize education, allowing global access for many who would have been previously denied a quality education. He also believes that the best learning occurs when the learner is so engaged that he or she is not even aware that learning is happening.
Shaeffer's current focus is development of the Academy of Art University's online MFA program, synchronous systems management, community building, and recruitment efforts.
In addition to his current university position, he is developing an online community for Alzheimer's patients and caretakers.


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Hey Pacer Fans,
When I click a thread the last poster to post in a thread is the first post of the thread.
I'd like it where I click a new thread the OP comes up. Then follow up comments in list format. This is how it usually always is in every forum and I am not sure why it isn't standard here.
Hopefully I explained that well enough, but I am not computer savvy and dont see how I can change it, .


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Wednesday, 30 March 2011
AB-Inbev *hearts* Goose Island. So now what do we do?
I know I'm probably the last beer blogger on earth to weigh in with a comment on the news that AB-Inbev has bought Goose Island, but comment I must - even if I repeat what everyone else has said.
At the outset it looks tricky: I've criticised AB-Inbev more than any other macro, not out of any prejudice, but simply in response to their actions. And Goose Island is one of my favourite brewers in the world, with their IPA my standard issue secret weapon for converting people who 'don't like' beer.
AB-Inbev do not like beer. Most people I have met personally who work for the corporation don't even drink it. I have argued with AB-Inbev marketers, trying to convince them that, if you want to make money from selling beer, you must recognise that it is not like other grocery products - that it has more romance, charm and mystery around it, that people take a greater degree of ownership in beer brands than they do in other product sectors. And those marketers have disagreed with me, stating categorically that they feel beer is no different from any other product and can be standardised and treated exactly the same. Stuart Macfarlane, CEO of AB-Inbev UK, has said that he works not for a brewer, but for an FMCG marketing company that happens to sell beer. It's a company that has an industry-wide reputation for being a ruthless cost cutter - after all, their relentless expansion has to be paid for somehow. The tragedy of Stella Artois is that it was once a special beer, and the last ten years have seen every single ounce of value stripped from that beer. AB-Inbev is also a company where, if you are an employee and you are seen drinking a beer from a different brewer - even on your own time, off the clock, when the company is not paying you - this can be, in the words of more than one former employee, "a career ending move." (Apart from anything else that completely transgresses employer-employee relationships, making working for AB-Inbev a form of indentured slavery, and I look forward to the day when some ex-employee sues their asses over this disgraceful policy. And if what I am saying is not true, I invite AB-Inbev to sue me for libel. I'm not short on potential defence witnesses.)
So no - I don't think it's good news that a mean, ruthless, cost focussed, heartless, acquisitive, jealous company run by people who don't even like beer has bought one of the best craft brewers in the world.
But this is not because "they're a macro" - it's because of the specific organisational policies and practices I've outlined. Interbrew in the old days were not like this. Not all AB-Inbev's competitors are like this. My point is, it's not about how big they are, it's about what they do - it's about their record.
I can only hope that people on Twitter who talked about their Goose Island beer 'turning from a micro to a macro' when they were half way down a pint were joking. As many people have pointed out, AB have long had a stake in Goose Island - they've just upped the size of that stake into a controlling interest. If your problem with this is the mere association, the smell of a macro brewer, then - actually, you know what? You just stick with that. I'm not going to try to convince you otherwise. But I don't think you'll end up a happier drinker because of it. The Goose Island products that are currently sitting in your beer fridge, in your local craft beer pub, your supermarket or beer shop, are no different than they were a week ago.
This takeover occurred, weirdly, just two days after I finished a piece for Brewers Guardian on innovation and new product development. In that piece, I argued that the brand management culture of big companies is entirely different from the entrepreneurial spirit of smaller companies. One can manage and grow brands on a global scale, but is incapable of nurturing genuinely new ideas to market. The other is the opposite. If a big company really wants something fresh and new, the best way for them to get it is to buy it, once it's reached a point where it has proven to be a profitable and sustainable niche product that is ready to make the transition to something bigger. And if a small company wants to grow beyond that point, the best thing they can do is to sell to a company that has processes, channels and people in place who know how to do that.
I think it's a perfectly valid argument for a craft beer fan to say, "Yeah, but we don't want them to grow! We want them to stay small and crafty." It's your opinion - beers are built by fans and fans have a say, and God knows, I'm all for supporting small companies because they are not multinationals. But remember, when a big company buys a small company in this way, the small company also wants to sell. If the people who built this thing from scratch, who devoted 20 years of their lives to it, decide this is the next step in the evolution of the business, you have to respect that.
So where does all that theory leave this particular acquisition? I'm in total agreement with Nigel Stevenson of James Clay, the importers of Goose Island into the UK. He says,
"Anheuser-Busch has acquired an American brewer of high acclaim, we thereby feel they recognise the potential within this market and appreciate that genuine craft beer brands cannot be 'invented' by a large Multinational organisation.
"At James Clay we are immensely proud to have been involved in Goose Island's growth and development over the years. We urge Anheuser-Busch to respect the culture of experimentation and innovation that has made Goose Island the world renowned brewer it is today. James Clay will continue to work with Goose Island in the UK but will monitor the impact of Anheuser-Busch closely."
To illustrate what this could mean: I'm currently consulting with another global macro brewer who is doing a deal not dissimilar to this (though on nothing like the same scale). It's not something I will cover as a writer because that would be a conflict of interest, and I can't say who it is until it goes public later in the year. But the macro in question is saying to itself internally, "We can't manage brands like this the way we normally do - if we apply our standard processes to the craft market, we'll only fuck it up." The deal therefore gives the craft beer access to far greater distribution channels and new investment in the brewery, and gives the macro a slice of the profit plus a little kudos, and the chance to see how craft beer works. But the macro has committed to not trying to interfere with how the micro makes its beer.
Similar deals occurred in Canada a few years ago, when Molson Coors acquired craft brewers Creemore Springs and Granville Island. These beers now have far greater distribution, but so far their craft brewing values and ways of doing things have not been compromised by pressure from the macro.
Will AB-Inbev follow a similarly enlightened process? Who knows? It would be nice if they told us - the only comment so far, unless I've missed something, is from the Goose Island guys. On the one hand, their record makes me very pessimistic. On the other, despite recent evidence to the contrary, they can't actually be total morons. If they wanted to make Craft Beer Lite, they could do so without forking out $39m for Goose Island. One can only hope they've bought it for the right reasons - that they recognise the value of craft beer, concede that they cannot do it themselves, and have a deal in place that will allow the craft brewer to continue doing that they do best, but on a larger scale.
I wouldn't bet money on this, but I have my fingers crossed. Either way, I'll be waiting until they completely screw it up before I start attacking them for having done so.
21 comments:
Is it a similar situation to an obscure band we follow achieving mainstream success? Even if their artistic integrity isn't compromised, they're no longer our secret and maybe, just maybe, no longer a means of displaying our superior, esoteric knowledge. Can't fight my gut reaction, however, which is emphatically 'Oh no...'
- 30 March 2011 at 09:32
- The Beer Nut said...
I think the micro-to-macro comment was at the expense of some of the more hysterical commentators on the beer message boards. That's certainly the spirit in which I re-tweeted it.
- 30 March 2011 at 09:33
- Sid Boggle said...
It'll be interesting to see who follows John Hall as GI top man (he's 68 I believe), or rather, who manages the process...
- 30 March 2011 at 09:44
- Pete Brown said...
BN - made me -ahem - Laugh Out Loud when I read it. Like all good satire, too close to the bone to simply dismiss as a joke.
Neil - I always compare beer with music and mostly feel the same way when bands go big - but not every time.
- 30 March 2011 at 09:46
- Rabidbarfly said...
Someone said on the day this was announced...I might be right or wrong, but just remember beer people big industrial breweries never make craft breweries, they just buy them...
Never was a truer word spoken.
- 30 March 2011 at 10:30
I love Goose Island IPA, one of my absolute favourites. I also enjoy their Christmas beer and their Winter ale. But then I used to enjoy Pilsner Urquell - a lot. Since it went Macro and the lagering process was tampered with it doesn't taste nearly as good. I'd hate to lose another classic because of cost cutting, but I can see it coming sadly.
- 30 March 2011 at 10:32
- Richard said...
How depressing, I'd never thought of a brewery as being in the FMCG remit.
Here's another depressing thought; Carling: great taste, every sip of the way'.
- 30 March 2011 at 10:41
- Martyn Cornell said...
I had a fascinating conversation with someone who works on the HR side of global AB-InBev a couple of days ago (not in the UK) who had total contempt for the company's treatment of its employees since it had acquired the brewer he originally worked for. So good luck Goose Island workers - you'll need it.
This is all part of the paradox that the larger a company becomes, the more it tends to concentrate on enhancing shareholder value in the short term (ie cutting costs, increasing dividends, driving up the share price), at the expence of shareholder value in the long term (ie building sustainable returns that will last throughout the next inevitable downturn). But that's a subject for another book …
- 30 March 2011 at 11:06
- Neil, Eating isn't Cheating said...
Totally agree about Goose Island IPA, it's an absolute classic.
Good of you to mention James Clay, they are fantastic guys. I emailed them a while ago about where Brooklyn Lager would be available on tap (after they landed the keg import deal) in and around leeds and they not only replied straight away but sent me a clickable google map with all the locations highlighted! Incidently we're spoilt for choice round here because of james clay being based nearby. A truly excellent importer and distributer.
I'm with you about AB-InBev aswell, I'd be massively surprised if they don't cock it up. The problem is that as you mention it may happen over such a long period of time that it isnt noticeable in the short term. And in ten years time when we're all muttering 'it doesnt taste like it used to' the new drinkers of the day will try to fob us off with claims of rose tinted glasses and misplaced nostalgia.
- 30 March 2011 at 11:15
- The Hearty Goodfellow said...
Picture the scene -
Goose Island IPA stacked up to the roof in 30 pack boxes alongside Stella and John Smith's in ASDA, Tesco, Sainsbury's and Morrisons.
The very same drink inside those boxes?
Maybe so.
But the very same drink experience for those that buy them?
I'd say that's why people mourn such deals.
- 30 March 2011 at 11:38
- Left Behind Child said...
It's important to remember that giant organizations such as AB-InBev rarely change quickly. The patter by which Goose Island will be treated has already been set. The absolutely unproductive drive tocsatisfy short-term needs, as Martyn notes, will dominate. Strategically, they cannot operate any way.
They crossed the Rubicon long ago.
- 30 March 2011 at 11:41
- Pete Brown said...
Hearty Goodfellow - if that is what they do with it, then I agree with you 100%. I just can't believe they'd the quite that stupid.
Probably a more relevant comparison would be what they did with Hoegaarden and Leffe - still not bad compared to mainstream, especially Hoegaarden, but not a shadow of what they were, nor what their competitors still are.
BUt as I said, I think ABI would be monumentally stupid to do even that with GI -there's just no rationale, apart from short term cost cutting - oh.
- 30 March 2011 at 12:35
- Joe Stange said...
"Interbrew in the old days were not like this."
Aside from your soft spot for Stella Artois, which I don't pretend to understand (and which I think we've discussed in person), what makes you say this?
At least on a superficial level, Interbew in the old days was very much like this in Belgium. It swallowed its share of smaller breweries.
- 30 March 2011 at 15:18
- Neil, Eating isn't Cheating said...
just read a comment from AB Inbev about the takeover. Thought you might be interested pete
- 30 March 2011 at 16:41
- Tandleman said...
Interbrew used to call itself "the world's local brewer". That wasn't that bad or that untrue, but ambition to be bigger was its undoing.
"Most people would succeed in small things if they were not troubled with great ambitions."
- 30 March 2011 at 17:28
Thanks for a very lucid and well considered commentary...quite refreshing compared to some of the things I've read in the last few days. Much of the vitriol expressed elsewhere has been the result of jumping to conclusions (although given the big company's track record, it is a very short jump). In any event, I'm glad you pointed out that 'big' doesn't necessarily automatically have to mean 'bad'. One can only hope that by some miracle of lucid thinking, AB-InBev does actually manage to grow the brands without 'screwing the Goose', as it were.
It would indeed be a real shame to see these really fine products dumbed down. Lets just sit tight for a bit and hope that AB-InBev surprises everyone and does the right thing with their new acquisition. If they do, this will be a good thing for "craft" beer, not a bad thing.
- 30 March 2011 at 17:34
- Adrian Tierney-Jones said...
As Chou en Lai supposedly when asked about the impact of the French revolution: it is too early to say…
- 30 March 2011 at 18:42
- Martyn Cornell said...
Joe Stange - my contact reserved all his vitriol for the Brazilians. Make of that what ye will.
- 30 March 2011 at 22:00
- Joe Stange said...
Martyn: Many of the Belgian beer enthusiasts I know love to blame the Brazilians for what's become of InBev, forgetting how much they despised Interbrew when it was around. It was a monster then, I suppose, but at least it was their monster. Also I'm from Missouri, where A-B was a monster but at least it was our monster. So I'm sympathetic with your source.
But what I read from the States is a lot of folks treating A-B Inbev as if it is still their monster. Oh, look, the makers of Wild Blue Blueberry Lager finally wised up and decided that craft beer is worth something! But this is a different monster entirely. While we're all reserving judgement, count me among the most cynical.
- 30 March 2011 at 23:04
- Jack R. said...
For me, the 3rd paragraph of "Ken's" comment to Andy Crouch's post on the buyout is most insightful. I direct your attention to: http://www.beerscribe.com/2011/03/28/why-the-ab-inbev-deal-is-good-for-craft-beer/comment-page-1/#comment-1970
- 31 March 2011 at 05:25
Creemore beer did not change after Molson Coors acquired it, there was even some innovation, e.g., the release of the Keller Beer version. It may be that macros now realize that they should maintain quality after buying small breweries.
On the other hand: there are so many brewers now in the U.S., Canada and U.K., and so much product diversity, that numerous options continue to exist for craft beer fans. True, it may be necessary to look harder for it in some areas, or drink more bottled vs. draft, but still there are many choices in Chicago and almost everywhere now (or areas accessible to same).
Just as an example, good as the Goose Island IPA is, numerous pale ales in the U.S. style are now available in the U.K. (Jaipur is top class). And other imports are available, bottled Sierra Nevada Pale Ale can be found in many pubs in London and even in draft form, I drank some in perfect condition not long ago at Southwark Arms at Borough Market.
There are always alternatives.
By the way I know there are different views on this but I think Urquell is still a remarkable beer. SAB Miller does a great job keeping that flag flying in my opinion.
- 31 March 2011 at 07:52


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Typhoon survivors raid Philippine storesTagum, Philippines
Published: December 9 2012 - 3:00AM
HUNGRY survivors of a deadly Philippine typhoon have raided shops and warehouses after aid deliveries were delayed.
Officials monitored the desperate scenes in the aftermath of typhoon Bopha's onslaught in the isolated southern town of Cateel, provincial official Cedric Daep said on Saturday.
''The food aid took so long to arrive that the locals broke into whatever building was left standing in search of something to eat,'' said Mr Daep, who was sent to the south by the government to help rescue and relief operations.
The typhoon killed more than 500 people and left hundreds missing across the south. About 393,000 people are said to be living in evacuation centres or receiving other forms of government assistance.
Warehouses and grocery stores were broken into in Cateel, a coastal town near where the eye of the typhoon made landfall on Tuesday.
Officials said damage to roads and bridges by floods and landslides trapped 150,000 people for three days in Cateel and nearby towns. They said almost all buildings were flattened or unroofed.
A Philippine Navy ship with 31 tonnes of emergency relief and 132 volunteer aid workers reached Baganga on Thursday, navy spokesman Omar Tonsay said.
There are claims that climate change, deforestation, poor planning and other factors worsened the catastrophe. Government officials said storm patterns related to climate change had put communities unaccustomed to strong typhoons in Bopha's path. But they also said the destruction had been exacerbated by deforestation from illegal logging and small-scale mining, as well as poor planning and confusion created by unclear maps of vulnerable areas.
Environment Secretary Ramon Paje said this week that about 80 per cent of the illegal logging ''hot spots'' in the Philippines are in Compostela Valley, the province that sustained the worst flooding. The denuding of mountains was seen as a key factor in the landslides and flooding.
Last December, more than 1200 people in the Philippines were killed by typhoon Washi, a powerful out-of-season storm that took an unusual southern track and surprised local officials, exposing thousands to flash floods.
Government officials at the time vowed to crack down on risks - such as illegal settlements in flood-prone areas - to avoid a repeat of the disaster. AFP, NEW YORK TIMES
This story was found at: http://www.smh.com.au/world/typhoon-survivors-raid-philippine-stores-20121208-2b2cu.html