text:
A Century After His Birth, George Gershwin's Music--From "Summertime" to "Embraceable You," Rhapsody in Blue to Porgy and Bess--is Attracting New Generations of Fans
"Nothing but hooky," Gershwin replied.
True, up to a point, for he was an indifferent and absentee student, and later a high school dropout. His schoolboy behavior led his teachers to consider him a hapless case, and his studious, slightly older brother Ira was often called into the principal's office at P.S. 20 in Manhattan's Lower East Side to account for his brother's poor scholastic record. George's major accomplishment at the time was street games; he was the acknowledged roller skating champion of Seventh Street, around the corner from the apartment on Second Avenue where Morris and Rose Gershwin raised their family.
It was here, in 1910, where the piano arrived that eventually led to George's leaving the High School of Commerce at the age of 15. Brother Ira was the intended victim. Ira, who wasn't keen on studying piano, watched apprehensively as the movers hoisted the upright from the sidewalk through the window of their second-floor flat. But the instant the piano was pushed into place, it was George who sat down and, as Ira recalled, "He played a popular tune of the day. I remember being particularly impressed by his left hand. I had no idea he could play and found out that despite his rollerskating activities, the kid parties he attended, the many street games he participated in [which resulted in the occasional bloody nose], George had found time to experiment on a player piano at the home of a friend on Seventh Street," Ira added. "Although our piano was purchased with my taking lessons in mind, it was decided George might prove the brighter pupil."
He was--with a vengeance. In his brief but dazzling career (he died at 38 of a brain tumor), George Gershwin composed hundreds of songs for dozens of musicals. Today, 100 years after his birth on September 26, 1898, many of his songs (often with Ira's lyrics) are still cherished standards: "Someone to Watch Over Me," "Fascinating Rhythm," "Summertime," "The Man I Love," "Embraceable You" and many more. His musicals and orchestral pieces such as Rhapsody in Blue, Of Thee I Sing, An American in Paris and his opera Porgy and Bess are considered among the greatest in American music.
And throughout George's career, there were always cigars. According to Gershwin's first biographer, Isaac Goldberg, he would ask the composer a question, "to which George, always through the fragrance of the omnipresent cigar, made a ready reply."
Charles G. Shaw, a writer for The New Yorker and Vanity Fair, interviewed Gershwin in 1928. By that time Gershwin was a celebrated, successful and frequently interviewed composer. Shaw revealed that Gershwin "likes ice cream sodas and Scotch highballs, with a casual cocktail on the side, but rarely touches loganberry juice. Don Sebastians are his favorite cigars," he noted, adding, "He seldom smokes cigarettes, save in feminine company."
Goldberg described a rehearsal of the Gershwin musical Strike Up the Band during its Boston tryout in December 1929, with George conducting: "The theatre is darkened, all but the stage. In the auditorium, only a few spectators...scattered, perhaps strategically, about the lower house. The composer had just ducked his way through the low door leading from under the stage to the orchestra pit. His gray felt hat and fur-lined overcoat are thrown across the top of the piano; his cigar--that ubiquitous cigar...already going full blast. Later in the evening it will serve as a baton; or George will blow songs through it."
Gershwin enjoyed cigars with his outdoor activities as well. As composer Kay Swift (his longtime mistress) recalled for Gershwin biographers Robert Kimball and Alfred Simon, "Riding. He did it well. He smoked a cigar at the same time. I told him it doesn't go with riding a horse."
At 14, Gershwin had not yet taken up cigars, but he sure had taken to the piano. Up to that time, he had gone through all of the neighborhood piano teachers and study books to no great advantage. But then he was introduced to pianist-composer-teacher Charles Hambitzer of Milwaukee. Years later, Gershwin told Goldberg "I was crazy about that man" who introduced him to Chopin, Liszt and Debussy. "He made me harmony-conscious. I went out, in fact, and drummed up 10 pupils for him."
The admiration was returned. "The boy is a genius," Hambitzer wrote to his sister in Milwaukee. "He's just crazy about music and can't wait until it's time for his lesson.... He wants to go in for this modern stuff, jazz and whatnot. But I'm not going to let him for a while. I'll see that he gets a firm foundation in the standard music first." As George's musicianship flowered, the boy who was mad about music was indifferent to schoolwork. Instead, he'd skip out of class and head up to West 28th Street off Fifth Avenue, where several music publishers clustered.
They were housed in four- or five-story brownstones, with the business offices on one floor and the other floors consisting of cubicles in which not-always-in-tune upright pianos were played by piano pounders, as they were called, who demonstrated the publisher's songs. During the summer, the clamor from dozens of pianos would spill out the open windows onto 28th Street. This inspired author-songwriter Monroe H. Rosenfeld to observe that it sounded like the noise of banging tin pans. The name Tin Pan Alley stuck, no matter where the publishers moved over the years.
Impressed with Gershwin's pianistic bravura, a friend in the music business introduced him to Mose Gumble, manager of the so-called professional department of Jerome H. Remick & Co., a prosperous publisher of popular songs. In May 1914, a month before the close of the school year, George Gershwin, age 15, joined the staff of Remick's at the then considerable salary of $15 a week. He was the youngest pianist in the cacophonous Alley. He believed the work would keep his fingers in melodic-rhythmic trim (for his ambition was, under the tutelage of Hambitzer, to become a concert pianist); but while playing other composers' tunes, he also tried his hand at composition.
His first instrumental piece, written when he was 15, was a "Tango" for solo piano; a slightly earlier work, never completed, was a song, "Since I Found You." These efforts reveal an ambitious youngster exhibiting a predilection for crossing the musical tracks.
This talent was not encouraged at Remick. When Gershwin submitted one of his songs to Gumble, he was informed, "You're here as a pianist, not a writer. We've got plenty of writers under contract." Whereupon Remick & Co. lost a pianist. For about two years, Gershwin had endured what he later referred to as "the popular song racket," but what he wanted to do was write theater music, what he called "production music." Having discovered the theater songs of Jerome Kern, Gershwin was convinced by the rejection of his own song that he must escape from Tin Pan Alley. Of all the professionals--dancers, singers, comedians--for whom he performed songs at Remick, Gershwin warmly remembered two: a brother and sister dance team from Omaha, Nebraska, the Austerlitzes, soon to become known as Fred and Adele Astaire.
Adrift, Gershwin found work as an accompanist for such rising singers as Vivienne Segal and Louise Dresser and as a rehearsal pianist for shows with scores by his idols Jerome Kern and Irving Berlin. At the same time, he was turning out songs that got some attention and led to his first published song, "When You Want 'Em, You Can't Get 'Em, When You've Got 'Em, You Don't Want 'Em"; the lyrics were written by a friend named Murray Roth. The "Ems" were "girlies." This was the song rejected by Gumble, but with the aid of vaudeville headliner Sophie Tucker, Gershwin and Roth were introduced to songwriter-publisher Harry Von Tilzer, writer of such heart-tuggers as "Wait Till the Sun Shines, Nellie" and "I Want a Girl Just Like the Girl that Married Dear Old Dad." To the joy of the fledgling writers, Von Tilzer took their song.
Gershwin was quickly introduced to the business of music publishing: "Murray Roth got an advance of fifteen dollars on the song. I waived an advance, wanting royalties--glamorous word!--in a lump sum. After some time I went and asked [Von Tilzer] for a little cash on the song. He handed me five dollars. And I never got a cent more."
He fared better with singer Vivienne Segal's help. She booked him a concert at New York's Century Theater, where the musical Miss 1917 was struggling for survival. The score was by Kern and another giant, Victor Herbert; Segal was in the cast and Gershwin had been the rehearsal pianist. With the theater dark on Sunday nights, producer Florenz Ziegfeld added to his receipts with concerts. According to Ira Gershwin's diary, on November 25, 1917, "Geo played for Vivienne Segal who took him out for a bow. She sang 'There's More to the Kiss than the X-X-X' [the x's indicate the sound of a kiss] and 'You-oo Just You,' both with lyrics by Irving Caesar." The second song was published by, of all companies, Remick's.
Fortunately for Gershwin, Harry Askins, manager of the Miss 1917 company, was a good judge of song. He brought George to the attention of Max Dreyfus, who ran Harms, which specialized in the publication of show music (Herbert and Kern were Harms composers). On hearing some of Gershwin's songs, Dreyfus signed the 19-year-old to a position as staff composer at a hefty salary of $35 a week. If Harms published one of his songs, in addition to the weekly income Gershwin would receive royalties on publication. Seven months later, in 1918, Harms published its first Gershwin song, "Some Wonderful Sort of Someone," which brought in some agreeable royalties. That year George also wrote a song entitled "The Real American Folk Song (Is a Rag)," one of his earliest collaborations with his brother Ira, who wrote the lyrics.
Dreyfus was a power in the trade, and unique--he could actually read music. He was responsible for Gershwin's first show assignment; he even put money into the production. It was called Half Past Eight and starred a popular comic named Joe Cook. Gershwin's contribution was a handful of songs, now forgotten. A young producer named Edward B. Perkins had brought the show to Dreyfus with several finished songs. The show opened in Syracuse, New York, on its way to Chicago and then New York. The opening date was December 9, 1918; the show was a disaster and never left Syracuse. "The newspapers came out the next day," Gershwin ruefully recalled, "and I remember one saying 'Half Past Eight isn't even worth the war tax.'" Gershwin was lucky to get his fare back to New York after the show's five-day run. It was an unhappy introduction to the vicissitudes of show business.
Meanwhile, Dreyfus, certain that Gershwin would make his mark, continued to market his songs. His pluggers managed to get a few inserted into the scores of musicals being produced at the time. In 1919, Gershwin composed his first full Broadway score in La-La-Lucille!; the lyrics were penned by Arthur Jackson and B. G. DeSylva. The show was a success and boasted an excellent song, "Nobody But You." Later that year Gershwin had two songs in a revue, Demi-Tasse, at New York's Capitol Theater. The vaudeville-like songs and dances were presented onstage between showings of the Capitol's film of the week. Gershwin and his lyricist, Irving Caesar, stood in the lobby with piles of the sheet music. To their dismay, nobody bought the songs.
But early the following year, Gershwin went to a party at which the "World's Greatest Entertainer," as Al Jolson billed himself, was present. He was celebrating his return to New York after touring with his show, Sinbad, scheduled to reopen at the Winter Garden. It took little coaxing to get Gershwin to the keyboard, with his, in Goldberg's phrase, "omnipresent cigar" clenched in his teeth. He played brilliantly through his small but burgeoning repertoire to a responsive audience. When he came to the Capitol revue songs, Jolson's ears perked. He would include one that excited him ("That song's for me!" he exclaimed when he first heard it) into his show.
Early in January 1920, Jolson recorded that Gershwin song, "Swanee," which swept the nation and, in time, much of the rest of the world. Jolson's record sold more than 2 million copies and, with the singer's smiling face replacing the original Art Deco cover, the sheet music also sold in droves. The song was Gershwin's sole smash hit.
The Roaring Twenties dawned with Gershwin on Broadway composing full scores. "Swanee" brought him to the attention of a young producer, George White, whose musical revue, George White's Scandals, was filled with songs no one would remember.
Beginning with the George White's Scandals of 1920, Gershwin wrote music for five Scandals, creating one of his earliest adaptations of the blues, "On My Mind the Whole Night Long," in the first. In the 1922 Scandals he produced another hit in "I'll Build a Stairway to Paradise," with lyrics by B. G. DeSylva (who wrote most of the lyrics for the 1922 show) and Ira Gershwin, who had been disguising himself since 1920 with the pseudonym Arthur Francis. (The older Gershwin used the names of his younger siblings so that no one could suggest that he was slipping into Tin Pan Alley on his brother's coattails.) Even more significant, Gershwin and DeSylva concocted a one-act mini-opera, Blue Monday, which, while it lasted only one night in New York, intimated the Gershwin to come.
That happened the year of Gershwin's last Scandals (1924), out of which came the enduring "Somebody Loves Me." Paul Whiteman, whose wildly popular band had been featured in the 1922 Scandals, had been impressed with Blue Monday, and suggested to Gershwin that he should write a "serious" composition in jazz. (Whiteman was known as "The King of Jazz" at a time when few had heard of Louis Armstrong or Jelly Roll Morton.) Gershwin agreed, then forgot about it.
Two years later, Gershwin was joltingly reminded of that casual exchange. The setting was the Ambassador Billiard Parlor at Broadway and 52nd Street in Manhattan; it was not quite midnight, January 3, 1924. Gershwin and Buddy DeSylva were shooting pool, relaxing after working on their musical, Sweet Little Devil, on its tryout tour in Boston before its New York premiere later that month. Nearby, seated on a tall stool, Ira Gershwin was reading the morning's New York Tribune. A brief item caught his eye: Whiteman Judges Named/Committee Will Decide "What is American Music". Read-ing further he learned that "George Gershwin is at work on a jazz concerto, Irving Berlin is writing a syncopated tone poem and Victor Herbert is working on an American suite."
This was news indeed to George--and to Berlin, for he was not struggling over a tone poem, and while Herbert did compose a Suite of Serenades, not one of them was American.
When he called Whiteman the next day for an explanation, Gershwin learned that the unexpected announcement had been forced on Whiteman because another bandleader was talking about doing a "jazz concert." Gershwin, still involved with Sweet Little Devil, could not see how he could write a concerto for a Whiteman concert scheduled for February 12. But Whiteman was persuasive, settling for any composition for piano and his orchestra and, further, offering the services of his arranger, Ferde Grofé, to assist with the orchestration.
Rather than work within the strict form of a concerto, Gershwin decided that he would compose an "American rhapsody." Ira suggested another title after visiting an art gallery that was displaying the canvasses of James McNeill Whistler. His familiar "Whistler's Mother" is, in fact, titled "Arrangement in Gray and Black"; another, "Nocturne in Green and Gold." So why not, Ira suggested, Rhapsody in Blue?
Gershwin began his Rhapsody in Blue (for Jazz Band and Piano) three days later, on January 7. Grofé haunted the Gershwin apartment on 110th Street daily for pages of the rhapsody in Gershwin's two-piano version (which Gershwin did for all his subsequent concert works--from these he worked out the orchestration). The fully orchestrated rhapsody was completed a month to the day after it was begun, five days before Whiteman's concert at Aeolian Hall in New York City.
It was the sensation of a long, often tedious, afternoon. Newspaper critics argued over it for days, questioning whether a man who wrote show music could compose a serious work. Subsequent concerts of Rhapsody in Blue took place at the hall in March and in Carnegie Hall in April, and then it went on the road. Gershwin stayed with the band until it reached St. Louis, then returned to New York to work on his next show. The notoriety and popularity of his very American and innovative composition brought him a contract from the New York Symphony for a full-scale concerto, resulting in the brilliant Concerto in F in 1925.
As it had begun in triumph with Rhapsody in Blue, 1924 closed with another hit, the musical Lady, Be Good! This was the first major collaboration on a Broadway show by the Gershwins. (By this time, Ira had shed his alter ego, Arthur Francis. By then everyone in the business knew who he was and, in addition, there was an English songwriter named Arthur Frances.)
Lady, Be Good! proved to be a landmark musical, short on plot but abundant in musical and lyrical quality; literate, breezy, youthful, of its time and in a word, Gershwinesque. Forty musicals were produced in New York that year, and after the Gershwins' hit, the sound of the American musical changed--it grew up. Just as Rhapsody in Blue opened the doors at Carnegie Hall to American composers, Lady, Be Good! paved the way for the likes of Rodgers and Hart, Cole Porter, Vincent Youmans and others. And, as they had hoped for years before, Fred and Adele Astaire were the happy stars who sang such songs as "Fascinating Rhythm," "The Half of It, Dearie, Blues," "So Am I" and, for a time, "The Man I Love," which was dropped from the show after it opened in Philadelphia, two weeks before its Broadway debut.
With the success of Rhapsody in Blue and Lady, Be Good!, George Gershwin was now the George Gershwin, which is how the less dynamic, less flamboyant Ira preferred it; sibling rivalry was no problem in their unique collaboration.
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- Doctors
- Washington
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- Dr. Thomas D. Chi
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Ratings for Dr. Thomas D. Chi
Dr. Thomas Chi has performed all my ankle surgeries with great care and satisfaction. He is very knowledgeable, friendly, honest and a very skilled surgeon. Without question, I would recommend him to my family and loved ones. During my past ankle surgeries, several nurses had only positive comments about Dr. Chi.
Everything with my experience with Dr. Chi and his office staff was excellent. I never had any issues scheduling an appointment with him. He was clear, concise and spent a great deal of time with me explaining the procedure and setting my expectations for post-op. He was very professional and I would have no qualms referring him to friends/family.
Di Chi is the very best doctor I have ever been to!!!!!! I just had a knee replacement. My Name is Dorothy Miller
He was very short and superfscial and not caring or sympathetic at all. His visual outlook of me and my diagnosis was completely different than my primary doctor. I think he is way to young and money grubbing and inexperienced. I sought another professional opinion!!!
Dr. Chi is the perfect doctor - compassionate, brilliant, empathetic and succinct! What a joy it was to find him, and I wish all doctors were like him.
Dr. Chi is the man! I have had 6 ankle surgeries with him. The results weren't what I was anticipating but I believe he is very comitted and dedicated to the optimum output. He takes a pragmatic approach and would do anything to help his patients. Never felt that I wasn't important. Marla and Dave are great on his staff. Great Doctor and Great Person!
Dr. Chi is the best. He's done two procedures on my knee so far and we are getting ready for the third. Not because he does shoddy work but because it's what my knee requires. He is knowledgable, he is informative, he is open to options (not surgery hungry), and he is patient. I would not trust my knee to anyone else. He is the best.
Dr. Chi is by far the BEST doctor I have ever had. Never before has a doctor spent so much time examining, questioning, explaining, diagramming, and answering questions. It is obvious that he cares about his patients and he remembers you and your case on subsequent visits. He carefully spells out all of the options, starts with conservative treatments, and only performs surgery when needed. He performed two separate procedures on me and I had full confidence in him each time. The outcomes were great. His excellent reputation is even known amongst the nursing and physical therapy staff.
Dr.Chi....what is there to say about him? WOW, after having two major operations with him I would not go see anyone else. He took time to explain everything to me, and also my parents. He even showed up early the day of my surgery to assure my parents as to what he was doing. HE was always willing to take extra time at my appointments even if that meant he would be behind for the last patient. I would trust my life (well maybe not my life) but any body part to this excellent skilled surgeon. I hold only the highest regard for him, and he has really helped to improve my overall funtion....His bedside manor was of the upmost concern, compassion, and honesty...You won't be sorry going to see him! HE IS GREAT! Lynne McClintock
Has an excellent bedside manner and very compassionate. Does not have the usual "I am God" mentality that most doctors do. Will explain everything to you in details with all your options. This doctor also listens to what you have to say. Did an awesome job on my knee surgery. I highly recommend him.
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NetWellness is a global, community service providing quality, unbiased health information from our partner university faculty. NetWellness is commercial-free and does not accept advertising.
Tuesday, September 26, 2017
Gum Diseases
Bleedng From Palette After Gum Graft
I had gum grafts done 11 days ago, and they took tissue from the roof of the mouth on both sides. The putty on both sides had fallen off within the next 4-5 days. They repacked it after the left side started really bleeding that morning. The next evening, the right side bled a little and the pressure from holding the gauze against it took the putty off. A periodontist saw it the next day and didn`t feel the putty needed reapplied. Since then, the right palette has bled on two separate occassions - both times, pretty substantially. I`ve used a tea bag with gauze pressed against it to stop it.
I`m continued to eat soft (pureed) foods, and no / minimal chewing. Is there anything else I should be doing.
I was told to resume wearing my nightguard once the putty had fallen off. Some of the nightguard hits the gum, but it isn`t sore or sensitive or directly touching where the donor site was.
Is it normal to still be having this much bleeding and to have it keep re-occurring? (I`m writing this as I`m sitting with the tea bag in my mouth waiting to go back to sleep as I woke up from the blood in my mouth.)
Thank you.
I hope that you are feeling better by now. Generally this type of bleeding can be controlled with pressure. If you cannot control it with pressure or if you have swelling in the palate, then you should definitely call your periodontist. Swelling generally means that it is bleeding inside the tissue and it needs to be controlled before it causes possible major complications.
You should be healed by now and you should not have any more discomfort.
Binnaz Leblebicioglu, DDS, MS, PhD
Associate Professor of Periodontology
College of Dentistry
The Ohio State University


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New Delhi, Oct 18 (IANS) Congress leader Digvijaya Singh Friday attacked "Gujarat model of development" promoted by BJP's prime ministerial candidate Narendra Modi and said Gujarat has one of the highest per capita debt in the country.
"Gujarat government has highest per capita debt liability which means every citizen of Gujarat has more debt to pay than citizen of any other state," Digvijaya Singh said Friday.
"Would Modi acolytes please respond?" he asked.
"Yes, they would with more `Galis' (abuses). No issue. Gujarat Model of Development must come in public domain," he said.
Digvijaya Singh quoted the planning commission to say that outstanding liability in Gujarat was 25.20 percent of the Gross State Domestic Product, compared to 24.13 percent in all states.


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Tom HEATON: Only fairly routine stuff in first half, beaten by decent strikes in the second 6
Kieran TRIPPIER: Volleyed over from early corner. Delivery into danger areas up to usual high standard 8
Michael DUFF: Scored first goal in over a year. Header off the line from Novak at death 8
Jason SHACKELL: Headed out Burke's cross to deny Birmingham the chance of a third equaliser 7
Ben MEE: Had to be on ball against Burke to close down and intercept. Worked well with wide men 8
Ross WALLACE: Earned his first start since August and had a hand in the opener 7
Dean MARNEY: The definition of relentless, and got his rewards with another important goal 7
David JONES: Pressed persistently to keep Huws at bay in midfield. Goal came out of nothing 6
Scott ARFIELD: Covered a ridiculous amount of ground, giving defence runaround, Snatched at late chance 7
Sam VOKES: In the right place at the right time to score. 8
Danny INGS: Had to search for the ball at times and linked well with Trippier in right channel. Limped off 7
SUBS: JUNIOR STANISLAS (for Wallace 62) Subs not used: Alex Cisak, David Edgar, Michael Kightly, Keith Treacy, Kevin Long, Ashley Barnes.
BIRMINGHAM (4-1-2-3): Darren Randolph; Jonathan Spector, Will Packwood, Paul Robinson, Tyler Beckett; Olly Lee (Federico Macheda 60) Tom Adeyemi, Emyr Huws; Chris Burke, Lee Novak, Andy Shinnie (Nikola Zigic 80).
Subs: Colin Doyle, Aaron Martin, Jordon Ibe, Paul Caddis, Albert Rusnak.
REF WATCH James Linnington was crowded out by Burnley players after Macheda made it 3-3. Appeals for handball ignored BOOKINGS Lee 34 (Birmingham)
MICHAEL DUFF: Defender couldn't have done much more to secure a win for Clarets. Big contribution at both ends
VILLAIN Federico Macheda: Came off the bench to spark Birmingham fightback. Seemingly handled before making it 3-3 deep into stoppage time
KEY MOMENT Macheda's introduction. The home side had shown no end product beforehand


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I agree, too early to pass judgement on Dorsey. He looked like he was having trouble keeping his footing. I doubt running up the gut with the second team line is how Tom Moore is planning on utilizing him much this year.
Here is some more on Ed Johnson, Ugoh and the other rookies performance:


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Phase II Trial of Sunitinib (SU011248) in Patients With Recurrent or Inoperable Meningioma
This study has been completed.
Memorial Sloan Kettering Cancer Center
Dana-Farber Cancer Institute
University of Virginia
University of Pittsburgh
Information provided by (Responsible Party):
Memorial Sloan Kettering Cancer Center
ClinicalTrials.gov Identifier:
First received: December 26, 2007
Last updated: December 21, 2015
Last verified: December 2015
- Full Text View
- Tabular View
- Study Results
- Disclaimer
- How to Read a Study Record
Detailed Description:
The purpose of this study is to find out what effects, good and/or bad, sunitinib has on patients and their tumors. At this time, no drugs are routinely used to treat meningioma, hemangioblastoma or hemangiopericytoma. Only surgery and radiation therapy are known to be useful.
Sunitinib is a drug approved for advanced kidney cancer. Sunitinib is also being studied for other tumors. It may be useful in the treatment of brain tumors because it can prevent formation of new blood vessels that allow tumor cells to survive and grow.
|CNS Cancer Meningioma Intracranial Hemangiopericytoma Hemangioblastoma Neurofibromatosis
|Drug: Sunitinib
|Phase 2
|Study Type:
|Study Design:
|Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
|Official Title:
|Phase II Trial of Sunitinib (SU011248) in Patients With Recurrent or Inoperable Meningioma
Resource links provided by NLM:
Genetics Home Reference related topics: neurofibromatosis type 2
Drug Information available for: Sunitinib malate Sunitinib
Genetic and Rare Diseases Information Center resources: Meningioma Neurofibromatosis Neurofibroma Neurofibromatosis Type 1 Neurofibromatosis Type 2 Hemangiopericytoma Hemangioblastoma Capillary HemangioblastomaU.S. FDA Resources
Further study details as provided by Memorial Sloan Kettering Cancer Center:
Primary Outcome Measures:
- Overall Objective Response [ Time Frame: 1.5 years ]Determine the overall objective response
|Study Start Date:
|October 2007
|Study Completion Date:
|October 2014
|Primary Completion Date:
|October 2014 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: Treatment
Sunitinib will be administered at a dose of 50 mg orally once daily for four consecutive weeks, followed by a two-week rest period. Intra-patient dose reduction may be required depending on the type and severity of individual toxicity encountered. Imaging studies will be performed after every other cycle. Patients may continue on study as long as they are tolerating treatment and in the absence of disease progression.
Drug: Sunitinib
The study drug will be administered on an outpatient basis. The starting dose will be 50 mg daily for 28 days (4 consecutive weeks) followed by 14 days off for patients not on CYP3A4 inducers or inhibitors. A cycle equals 42 days.
Other Names:
Detailed Description:
This is a phase II study of Sunitinib in patients with recurrent or inoperable meningiomas. An exploratory study will be performed for patients with recurrent hemangiopericytoma or hemangioblastoma. There will be approximately 50 patients enrolled on this study (40 meningiomas and 10 hemangiopericytomas/hemangioblastomas). The treatment plan is to use daily SU11248 at a dose of 50 mg, using the established schedule of 4 weeks of treatment followed by two weeks of rest period, forming a six-week treatment cycle. A medical professional will see each patient at least every six weeks while on the medication for toxicity assessment and physical examination. Extent of disease evaluations will occur at baseline, two weeks, twelve weeks, 24 weeks, and every twelve weeks thereafter. These evaluations will include MRI of the brain (or CT head if a patient cannot undergo MRI) and MR perfusion.
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Histologically proven recurrent meningioma or intracranial hemangiopericytoma or hemangioblastoma. This includes benign, atypical, or malignant meningioma; patients with neurofibromatosis type 1 or 2 may participate.
- Patients with classic radiographic picture of meningioma may also enroll if not surgically accessible. In this instance the patient must be reviewed at multi-disciplinary brain tumor conference including neurosurgery and neuroradiology to determine that the patient is appropriate for this study.
- Unequivocal evidence for tumor progression by MRI (or CT scan if MRI is contraindicated). The scan must be performed within 14 days of registration.
- Steroids dosing - malignant meningiomas must be on stable dose for at least 5 days prior to baseline imaging. For patients with benign or atypical meningiomas, stable steroid doses are not required.
- Recent resection for recurrent tumor - patients will be eligible as long as they have recovered from the effects of surgery and have residual disease that can be evaluated. To best assess the extent of residual disease post-operatively, a CT/MRI should be done no later than 96 hours in the immediate post-operative period or at least 4 weeks post-operatively. If the 96 hour scan is more than 14 days before registration, it should be repeated. Because Sunitinib is a VEGF inhibitor that can carry many risks including thrombocytopenia, bleeding, hypertension, and stroke, patients must wait at least 14 days after surgery, without complication, before they may initiate study drug.
- Prior radiation therapy - patients may have been treated with standard external beam radiation, interstitial brachytherapy, or radiosurgery in any combination. An interval of ≥ 4 weeks (28 days) must have elapsed from the completion of radiation therapy to study entry and there must be subsequent evidence of tumor progression. Patients with prior interstitial brachytherapy or stereotactic radiosurgery must have confirmation of true progressive disease rather than radiation necrosis based on PET, MR spectroscopy or surgical documentation of disease.
- Patients who have not had prior surgery or radiotherapy for their meningioma will be reviewed at multi-disciplinary brain tumor conference including neurosurgery and radiation oncology to determine that the patient is appropriate for this study.
- Prior therapy: There is no limitation on the number of prior surgeries, radiation therapy, radiosurgery treatments, or chemotherapy.
- All patients must sign an informed consent indicating that they are aware of the investigational nature of the study. Patients must sign an authorization for the release of their protected health information.
- Age ≥ 18 years old
- Karnofsky performance status ≥ 60%.
- ≥ 4 weeks since prior RT, stereotactic radiosurgery, or chemotherapy.
- Required Initial Laboratory Values (within 14 days of registration):
Absolute neutrophil count (ANC) ≥ 1,000/mm3
- Platelets ≥ 100,000/mm3
- hemoglobin ≥ 8gm/dl
- Serum aspartate transaminase (AST; serum glutamic oxaloacetic transaminase [SGOT]) and serum alanine transaminase (ALT; serum glutamic pyruvic transaminase [SGPT]) ≤ 2.5 x local laboratory upper limit of normal (ULN)
- Creatinine ≤ 2.0 mg/dl
- PT, INR, and PTT ≤ 1.5 times institutional upper limits of normal
- Total serum bilirubin ≤ 1.5 - Patients with a history of NF may have other stable CNS tumors, such as schwannoma, acoustic neuroma, or ependymoma, but ONLY if these lesions have been stable in size for the preceding 6 months.
Exclusion Criteria:
- Patients with the history of any other cancer (except non-melanoma skin cancer or carcinoma in-situ of the cervix, unless in complete remission and off all therapy for the disease for a minimum of 3 years) are ineligible.
- Any prior TKI therapy (SU011248, Sorafenib, Semaxinib, Axitinib)
- Concomitant use of any other investigational drugs
- Concomitant use of enzyme-inducing anti-epileptic drugs.
- Concomitant use of St John's Wort.
- Any of the following within the 6 months prior to study drug administration: myocardial infarction, severe/unstable angina, coronary/peripheral artery bypass graft, symptomatic congestive heart failure, cerebrovascular accident or transient ischemic attack, or pulmonary embolism.
- Ongoing cardiac dysrhythmias of NCI CTCAE Version 3.0 grade ≥ 2.
- Prolonged QTc interval on baseline EKG (>450 msec for males and >470 msec for females).
- Uncontrolled hypertension (>150/100 mm Hg despite optimal medical therapy). Patients are excluded if they have an elevated diastolic, an elevated systolic, or both.
- History of intracranial hemorrhage.
- Pre-existing thyroid abnormality, with thyroid function tests that cannot be maintained in the normal range with medication.
- Known human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome (AIDS)-related illness or other active infection.
- Concurrent treatment on another clinical trial. Supportive care trials or non-treatment trials, e.g. QOL, are allowed.
- Ongoing treatment with therapeutic doses of warfarin (low dose warfarin up to 2 mg daily for thromboembolic prophylaxis is allowed).
- Pregnancy or breast-feeding. Patients must be surgically sterile, postmenopausal, or agree to use effective contraception during the period of therapy. The definition of effective contraception will be based on the judgment of the principal investigator or a designated associate. Male patients must be surgically sterile or agree to use effective contraception. Women of childbearing potential must have a negative B-HCG pregnancy test documented within 14 days prior to registration.
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00589784
Please refer to this study by its ClinicalTrials.gov identifier: NCT00589784
|United States, Massachusetts
|Dana Farber Cancer Institute
|Boston, Massachusetts, United States, 02115
|United States, New Jersey
|Memoral Sloan Kettering Cancer Center
|Basking Ridge, New Jersey, United States
|United States, New York
|Memorial Sloan-Kettering Cancer Center at Commack
|Commack, New York, United States, 11725
|Memorial Sloan-Kettering Cancer Center
|New York, New York, United States, 10065
|United States, Pennsylvania
|University of Pittsburgh Medical Center
|Pittsburg, Pennsylvania, United States
|United States, Virginia
|University of Virginia Health Science Center
|Charlottesville, Virginia, United States, 22908
Sponsors and Collaborators
Memorial Sloan Kettering Cancer Center
Dana-Farber Cancer Institute
University of Virginia
University of Pittsburgh
|Principal Investigator:
|Thomas Kaley, MD
|Memorial Sloan Kettering Cancer Center
More Information
Additional Information:
Keywords provided by Memorial Sloan Kettering Cancer Center:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on September 21, 2017
Additional Information:
|Responsible Party:
|Memorial Sloan Kettering Cancer Center
|ClinicalTrials.gov Identifier:
|NCT00589784 History of Changes
|Obsolete Identifiers:
|Other Study ID Numbers:
|Study First Received:
|December 26, 2007
|Results First Received:
|December 21, 2015
|Last Updated:
|December 21, 2015
Keywords provided by Memorial Sloan Kettering Cancer Center:
Brain Cancer
CNS Cancer
intracranial hemangiopericytoma
malignant meningioma
neurofibromatosis type 1
neurofibromatosis type 2
Additional relevant MeSH terms:
Central Nervous System Neoplasms
Neoplasms, Nerve Tissue
Neoplasms by Histologic Type
Neoplasms, Vascular Tissue
Meningeal Neoplasms
Nervous System Neoplasms
Neoplasms by Site
Nervous System Diseases
Nerve Sheath Neoplasms
Neoplastic Syndromes, Hereditary
Neurocutaneous Syndromes
Heredodegenerative Disorders, Nervous System
Neurodegenerative Diseases
Genetic Diseases, Inborn
Peripheral Nervous System Neoplasms
Peripheral Nervous System Diseases
Neuromuscular Diseases
Hemangioma, Capillary
Cytochrome P-450 CYP3A Inducers
Antineoplastic Agents
Angiogenesis Inhibitors
Angiogenesis Modulating Agents
ClinicalTrials.gov processed this record on September 21, 2017


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A recently completed audit by the Transportation Department's inspector general has found that the FAA's Civil Aviation Registry does not provide all of the information needed for aviation safety and security measures. According to the DOT IG, the FAA lacks the information it needs on the identity of noncitizen aircraft owners and has incomplete information on pilot certifications.
FAA regulations require owners to update or correct the information in their registry records periodically, but the agency does not check these reregistrations against the original records to ensure accuracy and regulatory compliance.
"We found incomplete registrations for about 5,600 aircraft, or 54 percent, owned under trusts for non-U.S. citizens," the audit report said. "As a result, the FAA has been unable to provide information on these aircraft to foreign authorities upon request when U.S.-registered aircraft are involved in accidents or incidents in foreign lands, as required by the Convention on International Aviation."
Similarly, the registry lacks complete information on pilot certifications, which makes it difficult for law enforcement officials to use the registry to conduct security screenings required by the Intelligence Reform and Terrorism Prevention Act of 2004, or to detect pilots who provide false information.
G.BENEKOS (not verified)
July 12, 2013 - 2:19pm
According to recent rules all aircraft have been reregistered last year and the new registration is valid for 3 years only so it is not possible that there is still incomplete info.
frank hendricks (not verified)
July 12, 2013 - 2:48pm
I contacted the FAA twice online, as per directions in the last couple years, to become current with my AC registration but I never got a response.... Should I Be concerned? When I looked up my reg. on AOPA, it stated "registration info. unknown", and I've had the same N# all along. They don't look any different on the side of my airplane.
pilot jeff (not verified)
July 12, 2013 - 4:57pm
If you don't recall sending the government any money, check the re-registration schedule at http://www.faa.gov/licenses_certificates/aircraft_certification/aircraft... You need to see when your N number expires. The last two groups are coming up. It appears that after December 31 2013 all aircraft should of been re-registered.
Ronald Smith (not verified)
July 12, 2013 - 5:04pm
It must be diffcult to house so many meatheads in one Federal Agency
Michael DeAngelis (not verified)
July 12, 2013 - 6:53pm
I have an owner who's aircraft registration expires in November. Her notice says to send it in by July 31 to avoid lapse, so all aircraft are not re-registered yet.
paul fusillo (not verified)
July 13, 2013 - 7:45pm
It is a wonder that any registrations are complete. This department is the worst gov't agency branch I have ever dealt with. They lose things. They mail correspondence to the wrong address, They take months to respond and just about never answer the phone. I dealt with them for 50 years and they are worse now than ever.
Joe (not verified)
July 24, 2013 - 1:38pm
frustrated; will be selling my J-3 soon... don't want to deal with it anymore!


text:
Posted 5 years ago
(169 items)
DCB inspired me to add another radio that I found not that long ago. This is for him and all the other individuals out there that like to collect this sort of thing.
Fortunately the exterior is in nearly perfect/mint condition. The radio also works. It is in great shape for its age and has a pretty cool design.
Thanks for looking my friends and have an awesome one.... : )


text:
Nuclear Waste Sludge Management; MPC References
Readers Wonder What is the Best Hardware to Use When Remotly Handling Nuclear Waste. Do You Know of Any Multivariable Predictive Control Books?
"Ask the Experts" is moderated by Béla Lipták, editor of the Instrument Engineer's Handbook (IEH). He is recruiting co-authors who will bring fresh blood and increase the globalized nature of his team of authors for the 5th edition of the IEH. He welcomes offers from qualified colleagues to prepare new or update existing contributions. Contact him at firstname.lastname@example.com.
Q: We have remote-handled, (relatively high activity), 35% solids, radioactive sludges in Oak Ridge National Laboratory's Melton Valley storage tanks from which we're going to extract (at 2%-11% solids concentration in the slurry), dilute to <5% solids in a hold tank, transfer to the process facility and solidify/dispose as radioactive waste at a pre-approved federal disposal site.
This sludge is potentially stratified and definitely heterogeneous in each tank. Its supernatant phase varies both across the tanks and across the extraction process. We're to measure flow, percentage solids and density in real time, having considered Coriolis and other meters. Also:
- Bulk density of the sludge is 1.4-1.6
- Density of the dry solids is 2.75-3 g/cc
- Density of the supernatant is 1.05-1.1 g/cc
- pH of the supernatant is 9-12 (most likely 11-12)
At the risk of sounding flippant, I believe the answer lies somewhere between "You can't get there from here," and "Other than that, Mrs. Lincoln, how was the play?" We're not optimistic regarding on-line techniques. We can design the extraction system with a recirculation loop (both for the monitoring instrumentation and maintaining particles in suspension), but that doesn't get us to the point of measuring percentage of suspended solids in a variable-density solution. Some level of transmissivity measurement might be possible, but this sludge has all the opacity of chocolate milk (once mobilized).
In the near term, we're looking to put a mock-up of the tanks and extraction system in place (non-radioactive) here, and will be in a position to test candidate measurement systems. So, we may end up with something contrived, but that also works. Any thoughts or suggestions on hardware would be appreciated.
Christopher Shannon
A: For mass flow detection, both Coriolis and ultrasonic flowmeters can be considered if the volumetric flow reading of the ultrasonic meter is multiplied with sludge density. If the pipe is large, ultrasonic, sonar and fiberoptic designs are good candidates. Sonar flow detection is used in downhole offshore oil and gas production.
A sonar meter has an array of sensors clamped onto the pipe, and detects the speed of eddies as they pass these sensors. All-fiberoptic flowmeters also have been deployed in applications for both flow and phase fraction measurement.
As to continuously detecting percentage of solids in applications where you know the density of the solids and of the supernatant, I usually calculate percent of solids by: % = (SP1-SP3)/(SP2-SP3), where SP1 is the specific gravity of the sludge, SP2 is the dry solids, and SP3 is the supernatant. Therefore, you need three density measurements and the corresponding sampling systems.
For the details of automatic sludge sampling designs, see Chapter 8.2 in Volume 1 of the 4th edition of my handbook.
You should keep in mind that measurements that work in a mock-up might not work when you apply them to the full-scale process. Also, I will have an article (probably the Sepember issue) on the state of the art of nuclear power plant waste disposal, which you might be interested in reading.
Béla Lipták
A: Have you had a look at the sonic meters from Cidra? They are being used in the oil sands to measure the four-phase slurry flows in 27-in. lines from the mine face to the extraction plants and then again in tailings. They are non-intrusive, and should do a good part of the job. I have copied John Viega of Cidra on this note, so he can respond directly as well.
Also, a company called Caltron, (part of Emerson now, I think) had a non-invasive capacitance probe installed between a pair of flanges that could provide water content.
Ian Verhappen
A: When I was at Oak Ridge, I developed a probe that measured density and temperature along the probe. This probe was based on ultrasonics; it used the torsional mode. The probe was non-circular; we used a flattened probe about the size of a thermocouple probe used in reactors. Any non-circular probe would work. I switched between extensional mode to measure temperature and torsional mode to measure the density of the fluid surrounding the probe. There is an equation describing the velocity of propagation that includes density of the fluid surrounding the probe. It sounds to me like this probe might have application in this project.
By the way, the probe was originally developed after the Three Mile Island accident to measure coolant level in a nuclear reactor. In that measurement, one can't measure coolant level because the coolant is always at the top. Where coolant is lost in a reactor is at the hot spot, i.e., the core. You would have, from the bottom of the reactor vessel, water, void fraction and then water. This probe was designed for that environment, and would have taken the place of one of the thermocouples in the reactor.
George N. Miller, P.E.
Q: Could you suggest to me some MPC (multivariable predictive control) literature (books, articles, white papers, lectures, etc.) that I can study in order to fully understand how to design, implement and maintain an MPC project?
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Bag of BallsProbability puzzles require you to weigh all the possibilities and pick the most likely outcome.
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text:
Rotation competition heating up
BOSTON -- The job that Red Sox right-handers Rubby De La Rosa and Brandon Workman have done as fill-ins while righty Clay Buchholz and lefty Felix Doubront recover from injuries has created some intrigue in the rotation.
While Buchholz is certain to return to the rotation once the club decides he's had enough time in his Minor League rehab assignment, there's a chance De La Rosa or Workman could unseat Doubront.
"It's a good problem to have, to have a lot of pitchers that are capable of helping us," said general manager Ben Cherington. "We have to get there. We'll see where we are when we get to that point. We're waiting on a number of things, we're waiting on word on Workman's suspension, figuring out how that plays into it.
"We'll wait and see how Buch does in his next outing, so we'll just have to wait on a few things before we can make any decisions. But if we have tough decisions to have, I'll take those tough conversations as opposed to the alternative of not having them. It's a good problem to have."
Perhaps Doubront could move to the bullpen, along with either De La Rosa or Workman. The Red Sox have expressed a desire to stop moving Workman back and forth, and would rather keep him starting the rest of the season.
"We wouldn't rule anything out," said Cherington. "In Clay's case, he's established himself as a Major League starter. Given what he's accomplished when he's feeling good, we want to give him every opportunity to stay in that role. The other guys have all done it, they're also all capable of starting, so we have to balance that stuff, see where we are a few days from now once we have more information on Workman's suspension, see how Buch does on his next outing and go from there."
Ian Browne is a reporter for MLB.com. Read his blog, Brownie Points, and follow him on Twitter @IanMBrowne. This story was not subject to the approval of Major League Baseball or its clubs.


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WORKSHOPS, character shows and art and craft sessions are among the exciting activities in store for kids next week as Merry Hill gears up for February half-term.
The Brierley Hill shopping centre is pulling out all the stops to keep shoppers and their youngsters entertained during the school holiday.
Kids and grown-ups alike can channel their inner pirates and fairies on Monday (February 17) with a Tinker Bell and the Pirate Fairy workshop.
To celebrate the release of the new Disney film, there will be lots of free themed activities to get stuck into between 10am and 3pm outside TK Maxx.
Super hero and popular children's character Tree Fu Tom will be taking a break from the enchanted Treetopolis to make a very special appearance at the centre on Tuesday (February 18) for a free show at Central Plaza.
Half-term also coincides with the centre's We Are Dining extravaganza and there are lots of foodie treats in store for shoppers.
Budding Picassos can put their spuds to work with a potato print t-shirt workshop on Wednesday ( February 19) and all week long families can take advantage of the delicious deals available throughout the centre thanks to Merry Hill's We Are Dining voucher booklet, which is full of offers to redeem at any of the centre's 50 eateries.
Kelly Reed, the centre's senior marketing manager said: "We have some fantastic activities planned for kids over the February half-term - we're sure there'll be something to suit everyone.
"We hope lots of our young customers pay us a visit to make the most of our jam-packed schedule."


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J.J. Hardy and Adam Jones homered off Justin Verlander, and Manny Machado added a double and two sparkling plays at third base to lead the Baltimore Orioles to a 5-2 victory over the Detroit Tigers on Tuesday night.
Hardy hit his third homer off Verlander (8-5) this month, connecting for a two-run shot in the fourth inning, and Jones added a three-run drive in the fifth.
Zach Britton (1-1) allowed a run and five hits in 5 1-3 innings after being called up earlier in the day from the minors to make this start.
Four Baltimore relievers finished. Detroit put two on in the ninth for Miguel Cabrera, but the Triple Crown winner bounced into a game-ending double play on the first pitch from Jim Johnson, who got his 26th save in 30 chances.
Verlander gave up five runs and seven hits in five innings. He walked four and struck out five.
Matt Tuiasosopo homered for the Tigers.
Machado hit his major league-leading 33rd double of the year and put on a nifty show with his glove, diving to his left to stop Brayan Pena's groundball in the third and diving the other direction to make a play on Torii Hunter's grounder the following inning.
Hardy had three hits. He homered twice off Verlander in Baltimore's 10-3 loss to the Tigers on June 1, and he opened the scoring Tuesday with a drive to left in the fourth. Machado led off the following inning with a double, and after Nick Markakis walked, Jones hit an opposite field homer to right to make it 5-0.
Machado also hit a single in the sixth, and he leads the major leagues with 101 hits. Cabrera has 98 after hitting two singles, but he was thrown out trying to stretch one of them into a double.
Tuiasosopo's homer in the fifth made it 5-1, and Cabrera came to bat later that inning with two on and two out, but he grounded out.
Verlander's ERA increased to 3.72. He struggled a bit in the middle of May but appeared to be back in form after throwing seven scoreless innings at Kansas City on June 12.
Verlander was unable to build on that outing Tuesday. Britton, on the other hand, gave the Orioles exactly what they needed when he returned from the minors to make his second big league start of the year.
Darren O'Day got four outs in relief for Baltimore, but he also allowed an RBI single by Austin Jackson in the seventh. The Tigers then caught a break. With runners on first and second and nobody out, Hunter hit a grounder to Machado, who appeared to tag Pena between second and third before throwing to second for a force. Pena was not called out, though, giving Detroit a first-and-third situation with one out.
Baltimore manager Buck Showalter came out to argue, but the point became moot when Cabrera and Prince Fielder both fouled out to end the inning.
NOTES: Michigan basketball coach John Beilein threw out a ceremonial first pitch. ... Machado made an error in the eighth, but it didn't lead to any Detroit runs. ... The Tigers agreed to terms with four draft picks from this year: RHP Corey Knebel, CF Connor Harrell, SS Steven Negron and RHP Chase Edwards. ... Baltimore LHP Brian Matusz retired Fielder to end the seventh with the only pitch he threw. ... Detroit's Rick Porcello (4-3) takes the mound against Baltimore's Chris Tillman (7-2) on Wednesday.


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Ekvasis of Atorvastatin (Antorcin®) Treatment in Patients With Acute Cardiovascular Events (EKVASIS)
This study has been completed.
Elpen Pharmaceutical Co. Inc.
Information provided by (Responsible Party):
Elpen Pharmaceutical Co. Inc.
ClinicalTrials.gov Identifier:
First received: January 14, 2013
Last updated: August 18, 2014
Last verified: August 2014
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
No Study Results Posted on ClinicalTrials.gov for this Study
|Study Status:
|This study has been completed.
|Study Completion Date:
|July 2014
|Primary Completion Date:
|July 2014 (Final data collection date for primary outcome measure)


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We asked you to vote and say whether you thought sprouts were 'here to stay' or 'gone with the wind'.
Sprout fever swept the nation and a whopping 75% of you voted sprouts 'Here to Stay'! It seems the majority of White Stuff fans will be tucking into a plateful of green goodness on the 25th.
Thanks to everyone who voted. The winner of our Brussels competition will be announced in the New Year so stay tuned!
In the meantime, here are some more interesting facts from our Sprout-O-Meter poll:
The passion for sprouts was shared equally between men and women
Turns out only 70% of Londoners like sprouts (close quarters? Urban warming?)
88% of people living in the Channel Islands voted 'yes' to sprouts.
The further north you go in Britain, the more people like sprouts. Lymington is the exception to this with its passionate 81% in favour of our green heroes.
Spare a thought for ladies from the capital heading north for Christmas.
28% of London lasses hate sprouts but 84% of North Eastern men voted for the veg. They might get blown away by the welcome up north!
80% of our international voters loved sprouts.


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Note: This item is more than seven years old. Please take the publication date into consideration for any date references.
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Media Contact: TPWD News, email@example.com, 512-389-8030
Feb. 24, 2010
Three Men Charged With Poaching on King Ranch
RAYMONDVILLE — A Willacy County grand jury has returned indictments against three Valley men charged with illegally killing a deer on the King Ranch.
Named in the indictments, which were based on an investigation made by South Texas Game Wardens William Plumas and Ira Zuniga, were Rene Efrain Flores, 67, a retired Willacy County resident; Carlos Carmen Garza, 71, a retired engineer and Willacy County landowner and Jesus Raymundo Valdez, 29, a McAllen attorney. All were charged with taking a wildlife resource (white-tailed deer) without consent of the landowner, a state jail felony. In addition, Flores was indicted on a Class C misdemeanor charge of not tagging a deer; Garza with unlawful possession of a firearm, a third-degree felony and Valdez with criminal trespass, a Class B misdemeanor.
Games Wardens became involved in the case on Dec. 12 when Plumas received a telephone call from an area rancher who reported seeing two men on the Norias Division of the King Ranch in the process of lifting a dead eight-point buck across a fence to two other men. The landowner and one of his hunting guides stopped and talked to the men with the deer, but left after they refused to say where they had shot the buck.
Working with a King Ranch security officer and a deputy constable, the two wardens found blood on the roadway where the witnesses had seen the deer being loaded into the back of a pickup. The wardens were able to follow drag marks and blood to the fence, where they also found blood and hair. Checking inside the fence, they officers found more blood as well as the point where the deer had been standing when shot.
The citizen who initially contacted Plumas identified one of the men he had seen and described the vehicle the deer had been placed in. A short time later, the wardens and other officers located the vehicle and interviewed its occupants — three men and a juvenile.
An untagged buck was found in the bed of the pickup truck, along with two bolt-action rifles and a semi-automatic pistol. The deer and weapons were confiscated while the three adults were released pending further investigation.
All three defendants are free on personal recognizance pending an arraignment hearing. The case will be handled by Willacy County District Attorney Bernard W. Ammerman.
While the tip in this case came directly to a game warden, anyone with information concerning a game law violation is urged to contact Operation Game Thief, the state's wildlife "crime-stoppers" program. The OGT program operates a 24-hour, toll-free hotline to report crimes, 800-792-GAME. Rewards of up to $1,000 may be paid to callers, who may remain anonymous. Rewards and hotline operations are entirely funded with private donations. For more information, visit http://www.ogttx.com/.
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Rio Art Students Travel to Cincinnati
April 1, 2013
A group of 15 art students and 3 faculty travelled to Cincinnati on March 29 to visit museums and attend a theatrical performance.
The trip began with a visit to Serpent Mound in Peebles, Ohio, the site of one of the most impressive earthworks in North America. In Cincinnati, students and faculty visited the Cincinnati Art Museum and the Contemporary Arts Center of Cincinnati. Each facility had a variety of exhibitions of interest to art students.
After the museums closed, the group attended a performance of A Midsummer Night's Dream, performed by the Cincinnati Shakespeare Company.


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Vice President for Mission Effectiveness
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Sister Jean Marie Cleveland graduated from Marian College, now Marian University, with a degree in mathematics in 1964. She earned a master's degree in mathematics from Purdue University in 1971 and a master's degree in pastoral studies from Loyola University of Chicago in 1988.
Sister Jean Marie taught mathematics at the elementary and high school levels for many years. She taught at Cardinal Ritter High School for four years and was the principal of Our Lady of Angels High School in Cincinnati, Ohio, from 1972-79 and Oldenburg Academy in Oldenburg, Indiana, from 1979-87.
In addition to her work in education, Sister Jean Marie nurtured and strengthened many young lives through her work as a parish life coordinator at St. Patrick and Holy Rosary parishes in Indianapolis. She was a member of the leadership team for the Sisters of St. Francis, Oldenburg. She is also an active leader in mission effectiveness at Marian University and in Marian University's "Rebuild My Church" program. Sister Jean Marie has a brother and sister-in-law and is blessed with three nephews, one niece, and eight great nieces and nephews.
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Marian University does not discriminate on the basis of race, ethnicity, color, sex, gender, gender identity, sexual orientation, religion, creed, national origin, age or disabilities in the selection of administrative personnel, faculty and staff, and students.


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Keep Your Eyes Peeled!These brain teasers rely on your ability to recognize groups of common attributes. For each of these puzzles you'll need to figure out why the words or letters are grouped as they are. Sometimes you will be asked to pick the odd-one-out or to place a new word into the correct group.
Four men were standing in a room introducing themselves to each other. Joe is an ophthalmologist, Sam is an otologist, Alex is an optometrist, and Steve is an optician.
Then, Julie walks into the room and says, "Wow, you're all eye specialists!"
Joe corrects her. Who does he point out as not being an eye specialist?
AnswerSam is not an eye specialist. An otologist is an ear, nose, and throat doctor who specializes in the treatment of dizziness, deafness, and tumors of the ear.
An ophthalmologist diagnoses and treats eye disorders; an optometrist specializes in refraction of the eyes to determine the extent of vision and prescribes glasses; and the optician cuts the glass or plastic to fill the prescription.
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I think the Colts can make a nice playoff run if they can retain everyone from the roster and pickup some nice additions in free agency and the draft. This team has the ability to do so
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I think the Colts can make a nice playoff run if they can retain everyone from the roster and pickup some nice additions in free agency and the draft. This team has the ability to do so
Smothered Chicken!
Sure we can. We were capable this year. No reason not to expect improvement.
Sent from my HTC6435LVW using Tapatalk 2
If they make all the right signings I don't see why we couldn't compete with the Texans, Patriots, and Broncos.
Forgetting about a division with 1/2 of the last eight AFC champions, the reigning Super Bowl champion (yes, they'll have salary cap issues), and the up-and-coming Bengals?
Why do the things that we treasure most, slip away in time
Till to the music we grow deaf, to God's beauty blind
Why do the things that connect us slowly pull us apart?
Till we fall away in our own darkness, a stranger to our own hearts
And life itself, rushing over me
Life itself, the wind in black elms,
Life itself in your heart and in your eyes, I can't make it without you
Offensive line must improve.
I expect them to slide backwards. They shouldn't have been 11-5.
Thats funny.
They have more money and younger proven talent now and you think they will be worse? I can understand if you think the schedule is harder or if the loss of BA is signifcant but they played to their potential IMO.
They will be playing with an offense that will be a lot more efficient and hopefully will result in more points than we had this year. And the defense should hopefully get better. I expect 11-5 again.
Don't ask Marvin Harrison what he did during the bye week. "Batman never told where the Bat Cave is," he explained.
Very positive.
Smothered Chicken!
Honestly, he's probably right. We will be a better team next year with a worse record.
I have a feeling we show improvement, but still exhibit growing pains with a young team and finish 10-6 or 9-7 due to a harder schedule.
Edit: I just saw we have the third weakest schedule next year based on 2012 results. That isn't always the best indicator but I think 10 wins is about right.
Last edited by LuckSwagger; 02-07-2013 at 01:47 AM.
Smothered Chicken!
It's not bad to be greater than the sum of your parts, so to speak, but it does suggest that there was some degree of favorable scheduling / good fortune was at work.
Given the favorable cap position and team youth, though, I'd expect actual improvement in talent and maybe a similar record, or perhaps 10-6. But that would specifically assume upgrades in the offensive line, which I think holds you back more than anything else.
The poster "pacertom" since this forum began (and before!). I changed my name here to "Slick Pinkham" in honor of the imaginary player That Bobby "Slick" Leonard picked late in the 1971 ABA draft (true story!).
not sure if we make it to 11-5, bash me if u want just what I think.... we rode ALOT of emotion this past season. Will be interesting to see how we spend our money/draft picks. Better team overall with a playoff spot but dont think we go 11-5
Edit Signature
Get back with me after our off-season. It all depends on what we put in place with the enormous amount of cap space we have, and what pieces we pick up in the draft, and trades, etc... the coaching staff is in place and I think it's a good one.
If we have an ideal off-season, I could see us pushing for a SB appearance as a best-case scenario, but that might be in the form of the 2013 Ravens, where we sort of back in by losing more than we should, and then make a run in the playoffs. We could easily have a worse record and still be a better team than last year. The bar has been set high.
There are two types of quarterbacks in the league: Those whom over time, the league figures out ... and those who figure out the league.
Having money to spend is great.
Except when you spend it on guys like Samson Satele, Tom Zbikowski, a 32 year old Cory Redding to a 3 year deal, Mike McGlynn, and Donnie Avery (the guy is awful) when you have scant money to spend in the first place. The Mathis deal isn't exactly great either. Freeman was a stellar signing though, I'll give him that. I like Grigson, his draft was great, I'm glad he's running the Colts.
He didn't spend free agent money wisely. And you know why? Because free agency is much more often than not an abject failure in the NFL. It is not the way to build a quality NFL roster.
We went 4-2 last year against the division.. Anything less than 4-2 in 2013 would be a disappointment. We will likely lose at Houston and will probably lose one against either Tennessee or Jacksonville.
We went 3-1 against the NFC North, which was very impressive. We play the NFC West this year and it will be hard to replicate that success considering we play at San Francisco and host Seattle. Plus you know that Arians will probably have a great game plan against Luck considering he knows him inside and out. Hopefully we can beat St. Louis. I'm going to say we go 2-2 against the NFC West.
We play the AFC West. The Denver game will obviously be tough. At San Diego certainly won't be easy. We should win against Oakland and Kansas City. I'm going to say 3-1 or 2-2.
The two games against the teams that finished in the same spot of their division are Miami at home and Cincy on the road. Should beat Miami, but Cincy will be tough. I'll go out on a limb and say we get a big road win in Cincy and go 2-0 against those two teams.
I'm going to say 10-6. We have some tough games: Denver, @ SF, Seattle, @ Arizona (their coach knows us well), @ Cincy.
This is a great point too. You're right, there isn't much point in answering this question until we see what moves are made. This question will be much more relevant in April.
I never felt like the ones he brought in were long-term solutions... they were stop-gaps and veteran presence for what he knew would be a very young, inexperienced team. I don't think any of those guys got very expensive or long-term contracts.
There are two types of quarterbacks in the league: Those whom over time, the league figures out ... and those who figure out the league.
Right, I mean we had to field a roster somehow......
Ofcourse, but like many people said certain thinks have to happen...
We have to have Luck on our side again, we have to mesh well, we have to get more talent at some positions, and we have to hope that our young guys develop.
With a new OC, new O-line coach, new guys coming in, the offseason will be critical. I still think the conference is tough so you may be able to push for a spot if you are 9-7, and making it to the playoffs is the most important thing.
One final thing we have to do is show consistency, especially on the road, if we can do all these things well then we should have a good shot at going far in the playoffs.
Why so SERIOUS
I don't think you will find a poster on here that thinks NFL FA's is the way to build. Drafting and smart FA's signing is the way to go. I would argue that Cory Redding , Mike McGlynn and Winston Justice were not bad signings given the production for the cost. Even Mathis and Wayne were productive and many of the signings were to add depth not all of them were considered starting material.
FA's can plug holes on a team that needs to address key positions and I can give you examples of teams in the past and present that have done just that. Grigson reminds me of a more frugal spender than a guy who will chase a Mario Williams name like the BIlls did last year.
Also keep in mind the Colts have to spend money to meet the league minimal salary floor anyway. Might as well get a good OG and solidify the line and maybe lock up another DB. Combine a couple of signings with another solid draft and their is not much of reason to the think the Colts can't improve in key areas.


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A sometimes contentious wrangle about fees paid by Fort Ord developers ended quietly — very quietly — Friday before base reuse directors.
The Fort Ord Reuse Authority board voted unanimously to approve a method for charging developer fees sought by developers, who said they needed the method's certainty for immediate projects and long-term plans.
"It's not just for The Dunes. It will help all developers' projects move forward," said Scott Hilk, whose Marina Community Partners is building the major mixed-use Dunes development in Marina.
The fees decision clears an immediate hurdle for pending plans for a multiscreen theater and more than 100 below-market-cost apartments in The Dunes.
FORA has been juggling its developer fees since August, when the board approved a then-controversial new policy. Proponents said the "formulaic approach" would give developers certainty about their costs and reduce the role of politics.
Critics contended the new system would give developers lower fees on top of a 27 percent decrease approved in 2011.
At the behest of county Supervisor Jane Parker, the board unanimously adopted "clarifying language" on the new fee process in January, which Parker said would better define FORA's authority.
That brought almost immediate fire from developers and several member cities, including Marina, Seaside and Del Rey Oaks, which have major Fort Ord developments in the works.
They contended the added language could push up fees to maximum rates and create more uncertainty for developers — the opposite of what FORA intended in August.
Last week, Parker was the lone dissenter in a 10-1 vote by FORA directors to go back to the fee process approved last summer. That required Friday's second vote, for which Parker was absent, that carried without comment.
Earlier in the week, Doug Yount, interim Marina city manager, said the proposal to go back to the system approved in August was critical to the buildout of the The Dunes.
Plans for a 10-screen theater just south of the Dunes regional shopping center have been in the works since 2008, and city officials in November said they expected construction to start by the end of 2012.
"The fee issue is important to the theater and all Dunes development, and all future development on Fort Ord," Yount said in an email.
"Pending the action Friday, the theater should start site work within weeks and hopefully open by Dec. 13," Yount said.
South County Housing, developer of 108 below-market-rate apartments in The Dunes, voiced displeasure with FORA stepping away from the fee system approved in August.
"We urge FORA to consider the consequences of allowing uncertainty to exist over the level of future FORA fees in achieving goals for both below-market and market-rate housing at Fort Ord," South County Housing president Dennis Lalor said in a Jan. 24 letter.
A FORA staff report said Marina representatives and Parker were unable to reach agreement on revised language.
Marina City Councilman Frank O'Connell said the fee system approved in August was better for developers in bringing certainty.
"They want to have consistency throughout (the FORA area)," he said.
Larry Parsons can be reached at 646-4379 or email@example.com.


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Hotel George V
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Location This hotel is located in the heart of Brussels on a quiet street, 15 metres from the Bourse and 100 metres from the famous Grande-Place. It is also conveniently situated for the De Brouckère subway station and just 10 minutes from the Exhibition Centre and the European Parliament. Guests will find shops, restaurants, bars and nightspots all 100 metres away and Brussels Airport is just 19 km from the hotel.
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Average price per night for this hotel for the following weeks
|9/24/17 - 9/24/17
|9/25/17 - 10/1/17
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|10/9/17 - 10/15/17
Services and terms: Hotel George V
Accommodation facilities
- Lift
- Bar/Café
- Nursery
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- Parking
- 24 hr Room Service
Standard Room Services
- Safe
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- Satellite TV
- Hairdryer
- Telephone
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Location: Hotel George V
In the heart of Brussels, this 3-star hotel is located in a quiet street, 15 metres from the Bourse and 100 metres from the famous Grand-Place. 1 kms to city centre 30 kms to the airport (brussels airport) 70 kms to the airport (brussels south charleroi airport) 15 minute walk to the nearest metro station (de brouckere) Close to the station (de brouckere)


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HyunA Shares What She Has Learned From Being A Singer For 10 Years And Counting
Unit Triple H, with HyunA and PENTAGONs EDawn and Hui, has been featured on the cover of Ceci Magazine along with an interview about their upcoming debut.
These three members seemed to have a close relationship with each other. Actually, before Hui and EDawn debuted as PENTAGON, HyunA maintained her friendship with them and encouraged each other in music.
Soompi.Display.News.English.300x250.BTF Soompi.Mobile.English.300x250.ATF
Now being in the same group under the name Triple H, all three of them said that they have high hopes of their promotion. EDawn said, Before our promotion began, we talked a lot with [HyunA] about the music, the concept, style, and more. I wanted to cause as little harm as possible to [HyunA]. At the same time, I am excited because I think this will be fun.


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A Main Line rabbi recounts the power of his experience among thousands of fellow pro-Israel supporters at AIPAC's national conference in Washington D.C.
"I am pro-Israel; I am AIPAC." Thus began the 2014 annual policy conference of the American Israel Public Affairs Committee. In an opening video clip, individuals of diverse backgrounds — Jewish, Christian, conservative, liberal, Republican, Democrat, African-American, Hispanic, mothers, grandfathers, sons and daughters, college students, and even former U.S. Sen. Joseph Lieberman — described their affiliation and love of the Jewish state of Israel.
It was a stirring kickoff to an energetic, enlightening, uplifting, purposeful and critical gathering in which more than 14,000 people from across political, ethnic and religious spectrums came together to re-affirm the crucial importance of a strong U.S.-Israel relationship.
In addition to the emotional "I am AIPAC" rallying cry offering particular identifications of politics and background, we met those in Israel who look beyond the specifics of one's identity to fulfill the universal moral mandate of the Jewish state.
For example, Dr. Masad Barhoum, the director-general of the Western Galilee Medical Center in Nahariya, spoke about treating more than 200 victims of Syria's civil war.
Muslims, Christians, Druze and Jews alike, Barhoum proclaimed, "Adam, l'adam – adam: A person, to another person, is just that — a person — a human being, in need of care." When it comes to caring for another person, Israel considers "no race, no ethnicity, no border," Barhoum said, adding, "The Jewish state may not owe anything to its neighbors who call Israel their enemy — but we help, nonetheless."
And this was just the beginning of the three-day event, which included such headliners as Sens. John McCain (R-Ariz.), Chuck Schumer (D-N.Y.) and Robert Menendez (D-N.J.), House Majority Leader Eric Cantor (R-Va.) and U.S. Rep. Steny Hoyer (D-Md.) — not to mention Secretary of State John Kerry and Israeli Prime Minister Benjamin Netanyahu.
It was the largest gathering in AIPAC's history — and the attendees included a large young contingent. More than 2,300 college campus leaders participated. Some synagogues and high schools have begun bringing teens to educate them to be strong Israel advocates amid the increasingly hostile anti-Israel environment on university campuses.
The positive energy in every room of the Washington Convention Center was palpable, but the gathering was not at all oblivious to the challenges that Israel advocacy confronts, including an increasingly unstable Middle East and an Iran, still sworn to Israel's destruction, still moving toward a nuclear capability that is an existential threat not only for Israel, but for the region and the world. Another challenge is the quest and hope that a lasting, secure peace can be achieved with the Palestinians, yet concern that the Palestinian leadership is once again insincere in the current negotiations, viewing the significant concessions Israel may face only as an incremental step in the ultimate goal of annihilation of the Jewish state.
The United States needs a reliable friend in this challenging region — and Israel has been and always will be this ally. The tone of the entire conference promoted unity and inclusivity in difficult times — an agreement that a Jewish, democratic state is of critical strategic importance not only for the Jewish people, but for the American people and for the entire peace-loving world.
That is why at this critical time, I, too, am AIPAC. I am a religious leader seeking to inspire a Jewish dynamism and a power of self-determination and pride that could not exist without a strong, secure Israel. I am a modern Jew who views with awe and appreciation the sacrifice of those who came before me to ensure that I can take groups through the united city of Jerusalem, the eternal capital of the people of Israel. I am an idealist, praying for peace, despite the obstacles. And yet, I am also a resolute pragmatist, realistic that the challenges to the peace and security that the Israeli public overwhelmingly desires must come with sacrifices, yes, but also lasting, enforceable assurances.
I am AIPAC because, as I tell my congregation, this event is the "best Israel experience, outside of actually being in Israel" — an annual reminder that many thousands of people, in every state, of every background, stand together in enthusiastic support of a strong, vital, U.S.-Israel connection — to proclaim: Am Yisrael Chai.
Rabbi Eric Yanoff is the religious leader of Adath Israel in Merion Station.


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Matt Kenseth and Kasey Kahne mastered the fast 1.5-mile track at Las Vegas Motor Speedway Sunday, proving that their teams have a handle on the new Sprint Cup car.
But others, like Jeff Gordon and Danica Patrick, have some serious work to do after miserable performances in the Kobalt Tools 400.
Here's a look at Sunday's winners and losers:
Matt Kenseth—Everyone knew Kenseth would be strong with Joe Gibbs Racing, but some wondered if it might not take a while. Kenseth and crew chief Jason Ratcliff answered that question emphatically with a win on Sunday. Kenseth has been fast in two of the first three races and suddenly looks like a serious championship contender.
Kasey Kahne—Kahne was in danger of getting off to another slow start after wrecking in the Daytona 500 and struggling at Phoenix. But he was dominant at Las Vegas, leading 114 laps. He looks like the driver to beat on 1.5-mile tracks.
— Slideshow: Kobalt Tools 400 photos
Kyle Busch—Busch also needed a good run after blowing an engine at Daytona and wrecking at Phoenix. He was a contender to win and made some typical Rowdy-like moves on his way to a fourth-place finish. Look for him to be back on top of his game next week at Bristol.
Carl Edwards—Edwards snapped a 70-race winless streak at Phoenix, but we needed more evidence that he is back and for real. We got it at Las Vegas, where he ran up front all day and finished fifth. He's for real.
Dale Earnhardt Jr.—Junior didn't lead a lap and never challenged the leaders at Las Vegas. In fact, he had the third-best Hendrick car. But he logged another top-10 finish—his third straight to start the season—and is off to a fast start. He's well on his way to another Chase appearance.
Danica Patrick—Two weeks after her thrilling and encouraging run in the Daytona 500, Danicamania has come crashing back to earth.
A week after crashing and finishing 39th at Phoenix, Patrick was terrible at Las Vegas, where she ran well in the Nationwide Series.
Patrick had to start 37th after qualifying was rained out and struggled from the start. She was lapped six times, her team had a penalty on pit road and she finished 33rd, bringing back memories of her woeful performances in her first few Cup races last year. Next up is Bristol. Oh, boy.
Denny Hamlin—Hamlin was the loser of the week after being fined $25,000 for criticizing NASCAR's new car at Phoenix last week.
Still angry over the penalty, Hamlin was hoping to get a bit of revenge at Las Vegas. Instead, he got an early speeding penalty that put him behind all day. He tried to catch up by playing fuel mileage, but that didn't work either, resulting in a disappointing 15th-place finish.
Jeff Gordon—No one yelled "loose, loose, loose" throughout the race more than Gordon, who could never get a handle on his car and finished 25th. This is a bad sign since the other three Hendrick Chevys ran up front all day.
Clint Bowyer—Bowyer's car was so off he plummeted through the field as soon as the green flag dropped. He lost a lap after pitting with an early flat tire and never recovered, finishing two laps down in 27th.
Greg Biffle—This was supposed to be a Roush track and Biffle was expected to be a contender after being fast in practice. Instead, he struggled to a 17th-place finish.


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Experience serenity in the heart of downtown with all the amenities of home. Rest and renew in our quaint 2 bedroom/1 bath bungalow. relax with a book in our cozy reading areas,picnic in the yard, or ...Read Full Description