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|April 26, 2006
Volume 8, Issue 9
|Midwifery Today E-News
"Woman-to-Woman Care"
Print Page
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In This Week's Issue:
Quote of the Week
"Childbirth being one's most significant life passage, those close to us when we open to birth a baby will never be forgotten."
— Robin Lim
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The Art of Midwifery
I had very bad heartburn the eighth month of pregnancy, so bad I couldn't sleep. I had to try to sleep with my chest and head elevated. Then I discovered fennel seed tea. A glass of fennel seed tea before bed would completely cure the heartburn.
— Anon.,
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Passionate Midwifery Education
Certified Nurse-Midwife or Direct Entry Midwife
We are blessed in the United States with many routes of entry into midwifery. I think this strengthens us overall because many brilliant programs have been started by maverick midwives. On top of that, our 50 different states are like 50 different countries. That can be negative or positive depending on which state you are in. CNMs (Certified Nurse-Midwives) are legal in all 50 states; however, in all but one state, you must have a doctor agree to be a back up. This is not always easy: because of the financial, medical and political climate, doctors don't always want to provide back up. Because these different routes of entry are a complex issue, I will take three columns to explain it. Today we will just let you know that there are differences. The next columns will give the advantages and disadvantages of each route.
A CNM generally becomes a nurse first and goes to a midwifery school which is associated with a university. There are also a couple of programs whereby the midwifery and nursing can be done in the same program; Yale is an example. In the state of New York there is also the CM which is a Certified Midwife who takes a non-nurse program. This degree is just getting going and is not useful in most other states. However, these midwives are well trained could take their CPM (Certified Professional Midwife) to work in other states. The American College of Nurse-Midwives (ACNM) is working on getting the CM degree accepted. This Web site will give you a run down of the different programs and where they are located: http://www.allnursingschools.com/featured/nurse-midwife/
Thirty years ago the other midwives were called lay midwives. This term has fallen out of favor, though some of us rather like the term. Marsden Wagner calls himself a lay doctor because he learned medicine by apprenticing! Apprenticeship is a key component of direct entry midwifery. Direct entry just means that nursing is not required. The Midwives' Alliance of North America (MANA) has done an incredible job of birthing a unique credential, the Certified Professional Midwife or CPM. The extra special component of this credential is that it does not require that you go to a school; instead you must take a written and skill test and document a certain amount of required experience. It can be done totally by apprenticeship. Having said that there are many unique schools and programs that have birthed to help you learn midwifery and get your CPM or other state certification. Go here for a chart of the legal status of direct entry midwifery, state-by-state: http://www.mana.org/statechart.html Remember, we are like 50 different countries. Midwifery Education and Accreditation Council (MEAC) accredits education programs. Their list of approved programs can be viewed here: http://www.meacschools.org/programs/programs.html Twenty-some states accept the CPM credential. There are many more programs whereby you can get your education; for a complete list to date you can purchase the next issue of Midwifery Today in mid-June 2006.
Many midwives in the United States are illegal or alegal. In my home state of Oregon, one is not breaking the law by being an unlicensed midwife. In the 70s the attorney general came out with an opinion that midwifery was not the practice of medicine. In many other states, midwives just help women have their babies and do not pay attention to the law, much like the midwives in the Bible! They find credentials mean restrictions to protect the credential. We will discuss this more later. Meanwhile, welcome to midwifery!
— love, Jan
To read all installments of Jan's column on midwifery education, go to our Better Birth and Babies Blog.
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Woman-to-Woman Care
Traditionally, birth was a very private affair in which only the most intimate of a woman's relations attended her in labor. Grandmothers, aunts and wise women of the village whom the woman most trusted were the ones expected to be there. In today's society, women are taught to place their trust in the medical model of childbirth and in medical professionals rather than in people with whom they are most familiar. They are taught to accept the place of birth that medical professionals choose (because it is their "safe place"?). That is a difficult and sometimes impossible transition for many women. It so seriously affects a woman's sense of the familiar that patterns of labor are changed, birth pain is intensified, outcomes are less predictable and birth comes to be regarded as a difficult and painful ordeal, fraught with danger. To complicate matters, if the woman is in an unfamiliar and therefore "not safe place," she will protect her baby by preventing it from being born—ceasing to contract, keeping her cervix closed and in general "failing to progress," one of the major reasons for unplanned operative delivery.
Those of us who are certain that a woman's home is the most suitable environment for her birth must be particularly aware of the influence we may have on the woman's sense of safety. The most well-meaning midwife may nonetheless be a "stranger" to the mother and a threat to her need for privacy if the midwife is not fully trusted by the mother well before labor ensues.
Midwives are able to maintain normalcy in birth and help bring about an optimum outcome for mother and baby because we provide both constancy and continuity of care. As the relationship between midwife and mother develops during the course of prenatal care, an increasing mutual trust creates a sense of safety and security. Communication becomes forthright and honest, and words flow easily between them. When it comes to the time of birth, rarely must we deal with psychological issues that may impede labor, because specters of the past have been met, dealt with and put in their proper place. Over the months preceding birth, through her manner, touch and words, the midwife has said such things to the mother as "I will never leave you," "I know you can do this work of birth," "I trust you to grow a beautiful, healthy baby." What comfort this is to the woman meeting birth for the first time, with so many questions!
Thousands of times I have sat with a young woman who is having her first baby. When her eyes gaze into mine and I can feel her contractions crashing through her body like tumultuous waves against the rock, and I know she doubts her strength to go forward despite her great desire to complete her task, I say to her, "OK, now you will have to walk on water." She grasps my hand a little harder and replies, "How far do you want me to walk?" Then, we walk together.
— Valerie El Halta, excerpted from "Reconsidering Our Preconceptions about Birth," Midwifery Today Issue 59
MIDWIFERY TODAY Back Issues are available online. Issue 59
Babies Need to Bond
Babies need to bond, and if the mother is not there, an object takes her place. And if the only comfort your baby has in her first crucial hours of life is an incubator blanket, then things, not people, become her primary source of comfort for the rest of her life. Have you ever wondered why the US is such a materialistic society? Perhaps it is time to turn our wondering gaze to the routine breaking of the mother-infant bond in US hospitals over the last 50 years.
Besides being obsessively attached to things, your maternal bond-deprived child will be at increased risk of high infant stress levels, as well as compromised infant immune system function. Dr. Sarah J. Buckley writes:
It is scientifically plausible that [the] entire hypothalamic-pituitary-adrenal (HPA) axis, which mediates long-term stress responses and immune function, as well as short-term fight-or-flight reaction, is permanently mis-set by the continuing high stress hormone levels that ensue when newborn babies are routinely separated from their mothers.
The unbonded child is also at increased risk of behaviors dangerous to himself, society, or both. Studies following bond-deprived babies into adulthood have shown conclusively that the breaking of the maternal-infant bond results in higher rates of criminality, violence, schizophrenia and suicide.
Concerning the fate of unbonded infants, Joseph Chilton Pearce writes:
The unbonded female might become neurotic and be unable to bond to her child properly, but the unbonded male goes very subtly mad. Unless rooted to the mother matrix, his other matrices cannot form, and his machinery loses its balancing mechanism, its governor. He runs amok. What the unbonded male does is spend his life turning back on that matrix, trying to force from it that which is lacking. And what is lacking is his source of personal power, his possibility and his safe space. Lacking these, he turns and uses his strength to rape. He rapes either crudely or with sophistication, that is, bodily, or intellectually, raping the earth matrix with technology…. The rapist himself does not understand the real hunger that drives him.
Anthropologist Jean Liedloff writes in her culture-bending book, The Continuum Concept, that it is only sufficient in-arms time with the mother that gives children the ability to develop into mature, tribe-oriented, nonviolent adults. Without this bond, children are lost. The great majority of art produced by the hospital-born "X" generation (notably song lyrics) reflects this lostness.
In the case of the mother, the breaking of the mother-infant bond results in higher rates of postpartum depression, child rejection and child abuse.
In her infinite wisdom, nature gives new parents and newborns the desire to bond, because bonding is beneficial to our species. Bonding creates a sense of oneness between family members, between mother and infant, father and infant, mother and father, siblings and infant, and siblings and parents. The family is the bedrock of human society and the strength of the individual. The hospital institution does not promote family ties because it has no interest in strong families. The hospital's unstated goal and creed is family division. Family division begets human sickness and creates the lucrative byproduct of "belief in institutional health."
Of all the crimes against nature and human life routinely committed in the hospital institution, the breaking of the mother-child bond is the most harmful to the individual, the family and society at large.
— Excerpted from the e-book Spontaneous Creation: 101 Reasons Not to Have Your Baby in a Hospital, Vol. 1, A Book about Natural Childbirth and the Birth of Wisdom and Power in Childbearing Women, by Jock Doubleday
To order a copy, send your tax-deductible donation to: Natural Woman, Natural Man, Inc., 323 E. Matilija, Suite 110-131, Ojai, CA 93023, USA (Be sure to include your e-mail address.)
Jock has offered $50,000 to the first person who sends him by e-mail a controlled comparative study published in a recognized industry journal from any country, in any time period, demonstrating hospital birth to be safer in any category (i.e., infant morbidity, infant mortality, maternal morbidity, or maternal mortality) for most mothers or babies than home birth with a midwife in attendance. For further details, go to www.spontaneouscreation.org/SC/50,000%20Reward.htm.
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Research to Remember
An Alan Guttmacher Institute study of adolescent American teen sexuality gathered data from interviews with 101 sexually active teen males ages 14 to 19. Of the young men surveyed, 43% were black, 15% were white, 15% were Hispanic and 11% were Asian. Although 75% of the young men had no plan to impregnate their sexual partners, 56% observed that there was some likelihood that pregnancy would result. The researchers commented that the needs and viewpoints of young men must be acknowledged and addressed when society works with the problem of adolescent pregnancy, and that the young men have the right to have frank discussions of reproductive issues with their caregivers and also parents and teachers and other community leaders.
— Pediatrics, September 2005
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Forum Talk
I delivered my first at 34 weeks, five days, due to severe preeclampsia. She spent 11 days (a relatively short time) in the NICU. I spent over seven days hospitalized. I'm now pregnant, 25 months between pregnancies. I am 17 weeks. I have seen a lot of specialists. I do not have underlying hypertension. I see my cardiologist next week just to verify that everything is perfect, and after that my next appointment is with the perinatologist for my 20-week ultrasound. After those two appointments, if all is well, I'm ready to cut everyone loose and work on having a natural, healthy pregnancy and birth. I live less than five minutes away from the nearest E.R. Is it even possible a homebirth midwife would think of "taking me on"?
— Anon.
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Birth, The Play
Dare to be BOLD on Labor Day weekend 2006?
Question of the Week
Q: I have read all the marvelous advice regarding uterine prolapse and wondered if anyone had any advice for urethrocele, prolapse of the urethra (but not the uterus). I have tried acupuncture, Chinese herbs, am currently going for osteopathy and doing Christine Kent's exercise programme, but am unable to reverse it.
The urogynecologist says it's mild; however, when I stand up I don't even have an opening at the vagina. There's just this "adder head" mass (as it's so nicely described) that obstructs the opening (but which thankfully is not outside the body).
(I am based in Toronto, in case anyone has pointers for services here.)
— Anon.
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Question of the Week Responses
Q: Has anyone out there had any experience with the autoimmune disorder, morphea, and pregnancy? I currently have a client who has it and it has been very difficult finding any information about its effect on pregnancy and pregnancy risk. As I understand it, and this is mostly from being educated by the client herself, morphea is a sister disease to scleroderma but does not affect the internal organs, just the skin. My client has an area of hardened scar-like tissue on her lower back but otherwise she has no problems. She is an acupuncturist and very well-educated about her condition.
At first I didn't think much of it, but I decided to run it past my backup OB just to make sure she would be low-risk. Once he heard that it was related to scleroderma he said that even he wouldn't take care of her, he would refer her to a perinatologist. Apparently he had a woman with scleroderma who ended up dying at 35 weeks or so because a blood vessel popped in her brain. I tried to explain to him that this condition was different because it doesn't affect the internal organs, so he recommended a perinatologist consult.
The first perinatologist I sent her to had no idea what morphea was but nonetheless recommended a whole slew of coag studies and genetic tests. I decided to get a second opinion and phoned a perinatologist in my area. He hadn't heard of it, but when I described my understanding of it to him and he did some quick research, he said that my client is right and it should pose no problems with the pregnancy or birth. I'm much more inclined to go with his assessment, but I'm wondering if anyone out there has ever dealt with this before and what the outcome was.
— Corina Fitch, LM, RN
A: I have a similar patch of hardened skin on one of my arms. I first noticed it during the pregnancy of my fourth child. It was then about a nickel-sized patch. I was referred to a dermatologist and even had a surface biopsy done on it. The term scleroderma was mentioned but not explained, and I had no idea of its seriousness or potential to affect internal organs. My midwife and doctors associated with her at no time expressed concern over the condition. Several different expensive creams were prescribed and were ineffective. Since it caused no discomfort I discontinued these treatments and have been simply living with it although it has enlarged but not manifested on any other parts of my body. I did at one time do a brief Internet search, but what I was able to find was frightening and no treatment or cure seemed to exist. Since it began I have given birth to five healthy babies with no problems relating to the patch on my skin that I am aware of. I recently realized there was a condition of coleostasis present, but that is another story. This query in Midwifery Today is the first I have ever heard of morphea, so of course now I am wondering if it might not be this instead of scleroderma that I am experiencing. I am not a midwife and not trained in any health related area. I would be very interested in learning any further information about morphea.
— Carla Barnes, Argentina
A: Your client should consider going to a certified homeopath. Homeopathy is a curative form of medicine and can safely be used during pregnancy. Since "morphea" is probably an inherited condition, or rather, a condition that she is susceptible to because of hereditary factors, her children will also have this tendency. Homeopathic treatment addresses the whole person, not just the physical manifestation of her symptoms, as disease, like cancer for instance, shows itself in well-documented mental and other physiological symptoms *years* before the pathology shows up.
Homeopathic treatment will also be beneficial to her pregnancy, labor and post-partum care. If she is not able to find a certified homeopath in her area, she is not without options. She can work with someone over the phone, since homeopathic treatment relies predominantly on the client's reporting of her own symptoms.
— Manfred Mueller, DHM, RSHom (NA), CCH
Q: I have used (alone and in a five-week preparation) blue cohosh in six of my ten births. Some of the babies were "in distress," but only one had meconium and all had good Apgar scores. I have read some bad press lately about blue cohosh as a "stressor" and possible heart compromiser. Has alternative medicine backed away from the use of this herb or is it still considered a good herb to use for preparation and in labor/delivery? My daughter is 21 weeks pregnant and would like to use the same five-week preparation that I used in my last birth, but she is hearing some pretty scary stories from my sister (also pregnant). [from Midwifery Today E-News Issue 7:19]
A: I am glad to see Midwifery Today addressing the safety of herbs for labor. I have several concerns.
I've wondered why anyone who promotes homebirth wants to routinely use herbs to induce or augment labor. When I refer to "natural birth," I literally mean natural—our womanly bodies birthing without intervention (including herbs taken internally). A homebirth does not equal a "natural birth" if blue and black cohosh are used to induce.
Having made that distinction, let's make sure when discussing safety we discuss route of administration, dosage and frequency. One birth provider might swear that a cohosh tea is safe, but only share, "Cohosh is a good tool in her practice." Another provider might interpret that as meaning, "A tincture or injection is just as safe." Obviously they are not equally potent options.
In my Breastfeeding Medicine-based practice I am seeing babies whose mothers report to me that they received various forms of cohosh in labor: teas, tinctures and injections (possibly even a cervical topical). I have noticed a trend with these babies: prematurity, cardiovascular distress, jaundice, meconium, failure to thrive, suck dysfunctions and hospitalizations. The mothers report to me contractions on top of each other, very intense labors and hemorrhaging. Many of these women are taking these herbs prior to 38 weeks and deliver in the 37th week. I am suspicious that many homebirth transports and neonatal admissions could be explained by the side effects of the herbals.
I think the author of this question answered her own question and observed in her own babies the same results I see. Distress and meconium are not necessarily routine problems of the neonatal period. In the author's case and in the cases I see they are iatrogenic and could have been prevented.
Incidentally, my own definition of prematurity is inclusive of all babies being induced prior to the onset of spontaneous labor even if it's an herbal induction.
How ironic it is that this question comes up in a VBAC (vaginal birth after cesarean) prevention issue of E-News. Most of your readers would educate clients not to take Pitocin or Cytotec if they attempt a VBAC to prevent uterine hyperstimulation. It is time to seriously consider the consequences of herbal induction and potential hyperstimulation and rupture in our VBAC clients.
Some midwives might rebuttal that use of these herbs is appropriate if a client is approaching 42 weeks, term rupture of membranes, or failure to progress. These herbs if used in these cases are probably safer than transport. But, I stress that if it comes to these situations then it is not just "routine" use, and the clients have a right to informed consent. The goal in using internal intervention in labor should be to use only what is needed and not more AND only if there is good reason.
As you see, I am very concerned about the use of the cohoshes. Let's not be too cavalier about their routine use.
— Denise Punger, MD, FAAFP, IBCLC
[Editor's Note: For more discussion about blue cohosh, see Midwifery Today E-News Issue 2:22.]
Responses to any Question of the Week may be sent to E-News at any time. Write to email@example.com. Please indicate the topic of discussion *and the E-News issue number* in the subject line or in the message.
In response to "Preparing for Breech Delivery," (Think about It, E-News Issue 8:6):
We need to know everything we can [when preparing for breech delivery]. I will probably be at a birth in a few days where no one will do a vaginal exam or even know until the very time of birth whether the baby is in the right position. Women should check for position and even have their partners check. We need to know how to get the head out safely since the head is the biggest part of the baby and [in a breech] comes out last. If the baby was breech and we knew before it was too late to get to the hospital, the mom could determine what she wanted to do. If she chose to stay home, I would want to stay with her and assist her in whatever way she needed me.
While I do not pretend to have say in it, she needs to committed to birthing [a breech] at home. If she has any doubt, then I would probe her to see if she is fearful. Or, at that point since she probably already has some fears I would want to find out what she feared more: birth at home or in the hospital where they can cut her open. That thought does not scare some people, and in fact they feel very safe with the knowledge that the doctor will be nearby to open them up and take the baby out. I too am very happy that that service is out there, but let's give a woman a fighting chance [to have a vaginal birth].
Childbirth is scary; it's hard. But that is what makes it so great!
— Natalie
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Midwifery Today: Each One Teach One!


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Dominique's Lemon Bichon ($3.75) is like an apple turnover with fresh lemon curd in place of apples. Devour carefully—the dustings of powdered sugar fly right off. There's plenty of the tart and sweet curd tucked into the pastry, ensuring that you get more than a kiss each in bite. Also keep your eyes peeled for his Pistachio Sticky Buns ($3.75), With buttery folds of a croissant-esque dough and a based of toasty, caramelized pistachios, these sell out early and rightfully so.
Dominique Ansel Bakery
189 Spring Street, New York, NY 10012 (map)
About the author: Originally from Honolulu, Kathy YL Chan blogs at Kathy YL Chan, where she chronicles her eats and travel adventures between Hawai'i, New York and beyond. She firmly believes that there is always room for dessert.

subset: commoncrawl


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MELBOURNE, AUSTRALIA--(Marketwire - October 20, 2011) - Prana Biotechnology (NASDAQ: PRAN) (ASX: PBT) today announced Dr. Paul Adlard, Head of The Synaptic Neurobiology Laboratory at The Mental Health Research Institute and Prana research scientist, has been awarded an NHMRC* Project Grant to study the benefits of PBT2 and other compounds in age-related cognitive impairment. The grant is titled "The role of metals in healthy brain ageing: identification of novel compounds to prevent age-related cognitive decline." PBT2 is Prana's lead drug in development for Alzheimer's and Huntington's Diseases.
"This highly competitive grant from the Australian Federal Government will fund the study of compounds including PBT2, researching effects on brain anatomy and biochemistry, and also cognition and behavior," commented Geoffrey Kempler, Prana's Executive Chairman. "Earlier this year, Dr. Adlard published a landmark paper in the science journal PLoS One**, describing how PBT2 restores healthy function to neurons damaged in an animal model of Alzheimer's Disease. I congratulate Dr. Adlard on his success."
Prana has previously reported that in older normal mice, that is mice that were not genetically bred to develop Alzheimer's, the cognitive decline normally associated with the ageing process was significantly improved or reversed by PBT2. This grant for $762,975 will allow Dr. Adlard to extend the evidence for the role of the biological metals targeted by PBT2, in both Alzheimer's Disease as well as normal age-related cognitive loss.***
The normal ageing process, together with age-related disorders such as Alzheimer's Disease (AD), is characterized by a progressive decline in many cognitive processes, with memory impairment representing one of the most debilitating features of both "normal" and "pathological" ageing. There are currently no effective long-term treatments, or even a defined understanding of how these deficits occur. "With this grant we will develop our hypotheses as to the cause and potential treatments of memory impairments, specifically linking synaptic zinc dyshomeostasis as a causative factor, and indeed as a therapeutic target, of this dysfunction. PBT2, already shown to bring cognitive benefit to Alzheimer's Disease patients may also improve the cognitive decline associated with normal ageing," commented Dr. Adlard.
*National Health and Medical Research Council
**Press release July 16, 2009
***Adlard et al (2011). "Metal Ionophore Treatment Restores Dendritic Spine Density and Synaptic Protein Levels in a Mouse Model of Alzheimer's Disease." PLoS ONE 6(3): e17669.doi:10.1371/
About Prana Biotechnology Limited
Prana Biotechnology was established to commercialize research into age-related neurodegenerative disorders. The Company was incorporated in 1997 and listed on the Australian Securities Exchange in March 2000 and listed on NASDAQ in September 2002. Researchers at prominent international institutions including The University of Melbourne, The Mental Health Research Institute (Melbourne) and Massachusetts General Hospital, a teaching hospital of Harvard Medical School, contributed to the discovery of Prana's technology.
For further information please visit the Company's web site at www.pranabio.com.
Forward Looking Statements
This press release contains "forward-looking statements" within the meaning of section 27A of the Securities Act of 1933 and section 21E of the Securities Exchange Act of 1934. The Company has tried to identify such forward-looking statements by use of such words as "expects," "intends," "hopes," "anticipates," "believes," "could," "may," "evidences" and "estimates," and other similar expressions, but these words are not the exclusive means of identifying such statements. Such statements include, but are not limited to any statements relating to the Company's drug development program, including, but not limited to the initiation, progress and outcomes of clinical trials of the Company's drug development program, including, but not limited to, PBT2, and any other statements that are not historical facts. Such statements involve risks and uncertainties, including, but not limited to, those risks and uncertainties relating to the difficulties or delays in financing, development, testing, regulatory approval, production and marketing of the Company's drug components, including, but not limited to, PBT2, the ability of the Company to procure additional future sources of financing, unexpected adverse side effects or inadequate therapeutic efficacy of the Company's drug compounds, including, but not limited to, PBT2, that could slow or prevent products coming to market, the uncertainty of patent protection for the Company's intellectual property or trade secrets, including, but not limited to, the intellectual property relating to PBT2, and other risks detailed from time to time in the filings the Company makes with Securities and Exchange Commission including its annual reports on Form 20-F and its reports on Form 6-K. Such statements are based on management's current expectations, but actual results may differ materially due to various factions including those risks and uncertainties mentioned or referred to in this press release. Accordingly, you should not rely on those forward-looking statements as a prediction of actual future results.


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Another adorable update from the Indiana Chihuahua!
Watch some raw video of adorable TurboRoo.
He's so cute!
Cuteness explosion.
Who could get enough of this cuteness?
Image of TurboRoo courtesy: Instagram (turbo.roo)
INDIANAPOLIS - Our Indianapolis sister station is following the story of TurboRoo, a tiny puppy with a huge following is still growing and thriving with just two legs.
RTV6 first looked into the story of TurboRoo last month. He was born without his front legs, and his owners surrendered him to The Downtown Veterinarian in Indianapolis.
The disabled puppy was so small that a cart was made from toy parts so he could be mobile.
Since RTV6 broke the story, TurboRoo has gotten his forever home. His tale has also gone viral, catching the eye of an engineer in San Diego who has made him a version of a mobility car.
Now, he's grown significantly. He can stand on his hind legs and hop. And he's a speed demon in his new cart. Watch some of our attached videos to see for yourself.
The latest cart has four wheels instead of two, and works the best so far. His adoptive mom, Ashley Looper, said TurboRoo just got the hang of it this week.
She says TurboRoo was very motivated to keep up with her other dog when they went out for a walk.
Now that he's a pro, the engineer is working on yet another version of the cart that will allow him to make turns.


text: More seriously though, this sounds like a major natural gas explosion, basically. Terrible, but fortunate that there were not more deaths. Natural gas explosions can be TERRIFICALLY powerful. If it were a plane crash, then there'd be pretty obvious debris in some of the many pictures now floating around the net. If it were a bomb... well, they'd be evacuating people over a considerably larger area in case of secondary devices. More likely there's just too much devastation for the time being to make a sure call on the cause yet, and it's also why there's arson investigators there.Putting all this together: The probability that every battleground state is exactly tied is roughly equal to the probability that, when one of the Florida electors reaches into the hat to draw a name, he or she is struck by a falling cocaine bale, the hat is hurled away within the next few seconds by a tornado, and the elector is obliterated minutes later by a meteorite impact.


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MaitriYNOD wrote:dzogchungpa wrote:OK, so the Dzogchen POV is that the Vajrasattva of Ngondro is a real Buddha, not just a method?
Whichever position you end up taking, please don't consider yidams to be "just" methods. They are methods. Existent or not, there is nothing meager or diminutive about the methods of the Vajrayana. To say something is provisional does not detract from its profundity. Confused beings must depend on provisional methods, they are what lead us to awakening.
Perhaps I should have been clearer about the fact that I have enormous respect for Vajrayana, and in particular, I think deity yoga is, potentially, an incredibly profound practice.


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When it comes right down to it, pesto is a personal thing isn't it? If you happen to try this recipe, I encourage you to adapt it to your own taste. I'm planning to use my version of sage pesto for things like stuffed chicken breasts or on roasted squash, and maybe in lasagna with spinach. This sage pesto is my entry for Weekend Herb Blogging #147, hosted by Katie from Thyme for Cooking. If you'd like to participate with an entry about cooking with herbs or unusual vegetables, check the new rules for Weekend Herb Blogging, and how to send your entry.
I have two kinds of sage in my garden, but I used this lovely purple sage to make the pesto. This type of sage is so attractive, you could easily plant it among flowers.
Sage and Pecan Pesto
(Makes about 4 cups sage pesto which I froze in ice cube trays to make 18 cubes pesto, about 3 T each. Recipe created by Kalyn with inspiration from many sources.)
3 large handfuls sage leaves, stems removed, washed and dried
3/4 cup unsalted pecans (or almonds)
1/3 cup chopped fresh garlic
1 tsp. salt
1/2 cup olive oil
2 cups coarsely grated parmesan cheese (or more)
Use cutting board and chef's knife to chop garlic and pecans. (They will get chopped more in the food processor so they don't have to be chopped too precisely.) Add pecans, garlic, salt, and parmesan to food processor and pulse until mixture is well combined but not completely pureed together. With food processor running, pour olive oil in through feed tube as you pulse, until the oil is blended with other ingredients. (Taste the pesto and see if you want more cheese, since sage is a strong flavor.)
If desired, freeze in ice cube trays or small containers. Will keep in the fridge for at least a week, or for months in the freezer. When my cubes are well frozen, I pop them out and seal them inside a plastic bag with the FoodSaver.
Baked Chicken Breasts Stuffed with Sage-Pecan Pesto and Feta from Kalyn's Kitchen
Cavatappi Pasta Salad with Walnut-Sage Pesto from Culinary in the Country
D.I.Y. Sage Pesto from The Kitchn
Sage Beef with Feta and Tomatoes from Mele Cotte


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Herbalife Shares Up on Icahn Deal
Nutritional-supplement maker Herbalife Ltd. agreed to name two of billionaire investor Carl Icahn's designees to its board, winning new support in its ongoing battle with another hedge fund manager.
Shares in the Los Angeles-based company were up 7.6% at $40.29 in 4 p.m. New York Stock Exchange trading. The stock is down 11% over the past three months.
"We are pleased to have reached this agreement and look forward to...


text: Ever wanted to learn how to create Drag & Drop Questions in your online courses? Join Dr. Allen Partridge, Adobe eLearning Evangelist for this discussion and demonstration of quiz creation using Drag & Drop Questions to tackle a variety of assessment scenarios in your eLearning. Learn the fundamental concepts behind drag and drop mechanics in eLearning and join the discussion of best practices for adding these questions to your courses. The session is available now – on demand. Just click the link to register and watch it now, free of charge.


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Lautner's homes have appeared in Hollywood movies, but the architect himself wasn't particularly well-known when he died in 1994. Still, in 2011 — the centennial year of Lautner's birth — his hometown of Marquette, Mich., has honored him with two exhibitions: one at Northern Michigan University's DeVos Art Museum and one at the Marquette Regional History Center. — NPR
John Lautner's homes have been featured in many movies, but few people actually know who the architect was who came up with the designs. His space-age designs were probably a favourite of the cinematic because the designs themselves look like something which might be dreamed up by a set... View full entry
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my family
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This Gif entitled my family was created from the youtube video 3 years ago. It uses 12 frames per second and is displayed at 640px resolution. This animated image plays for 10 seconds, was built with high quality and an estimated weight of 10.07 MB for download. This animation was originally created from the 2015 03 07 romeos 30th birthday video from 00:11 to 00:21.
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text:
THE SQL Server Blog Spot on the Web
It's been just over a week since Windows Azure announced the GA of Infrastructure Services, marking the beginning of a fully supported Infrastructure as a Service in Windows Azure, with SQL Server as a major component.
Pre-installed SQL Server VMs are available for pay-per-hour usage in the Windows Azure gallery. Currently Enterprise, Standard and Web edition VMs running on Windows Server 2008 R2 SP1 are available, with more SQL Server editions coming soon. SQL Server editions running on Windows Server 2012 images are also on the way. For more details on the scenarios and benefits of running SQL Server workloads on Windows Azure Virtual Machines, please visit the SQL Server blog post here.
We are very happy to announce that the updated technical documentation for deploying and running SQL Server in Windows Azure Infrastructures Services is now available online. When deploying SQL Server in Windows Azure Virtual Machines, we recommend that you follow the detailed guidance given in the new SQL Server in Windows Azure Virtual Machines documentation in the library. This documentation includes a series of articles and tutorials that provide detailed guidance on:
Over the next few weeks we are planning a series of blog posts to provide more detailed information on specific SQL Server topics. Subjects in the pipeline include: high availability, disaster recovery, performance, application migration and security. Let us know what topics you would like to see covered in this series by adding comments to this post.
SQL Server Team


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NEW ORLEANS — When he played in Washington, Carlos Rogers was regarded as the Redskins' No. 2 cover corner behind the flashier, overrated DeAngelo Hall. That impression hurt Rogers' value and kept him from being paid as he should.
Now into his 30s and after two seasons with the San Francisco 49ers, Rogers is appreciated a lot more. The 2011 Pro Bowler has so far earned every bit of the four-year, $29.3 million contract he signed that year to become the Niners' undisputed top corner.
As he prepares to play on the NFL's biggest stage for the first time, Rogers is appreciative of the long road it took to get there.
"I'm not like Randy (Moss) or Cowboy (49ers defensive end Justin Smith) where it's toward the end of my career," Rogers said Tuesday. "I hope not, but it being my eighth year and all that I've been through, just to top it all off right now to go to the Super Bowl is unbelievable."
The 6-foot, 199-pound Rogers was underused in Washington. San Francisco's 3-4 scheme has allowed him to show his versatility and be a more active playmaker.
"I play on the left side when most quarterbacks are right-handed," Rogers said. "I've played in the slot on third downs to take away some of those guys. They let me do some blitzing, and sometimes, I have to go play safety.
"They have given me a lot of opportunities to show a lot of my talent."


text:
Alanis Morissette's 'Ironic' Finally Becomes So in Parody
A New Version of the Popular Song Applies the Rhetorical Device Properly, for a Change
Alanis Morissette's 1996 hit song "Ironic" has agitated rhetoric snobs for years. Taking listeners through a series of unlucky coincidences—a rainy wedding, a no-smoking sign on a cigarette break, a failure to take good advice—the Grammy-nominated song is devoid of any literal irony.
In July, a pair of 24-year-old sisters from North Haven, Conn., rewrote the lyrics and recorded a shot-by-shot parody of the original music video. Rachael and Eliza Hurwitz's new version, "It's Finally Ironic," has been viewed on YouTube more than half a million times. "We fixed it for you, Alanis," Eliza coos in the spoof. "You're welcome."
The concept of irony has a way of befuddling people. Over the years, the word has come to be widely misused as a synonym for "unfortunate." By definition, though, irony implies that something has happened in the opposite way from which it was intended. "Rain on your wedding day is just bad luck," said Ralph Sneeden, an English teacher at Phillips Exeter Academy in New Hampshire.
Ms. Morissette has since claimed that the irony of the song lies in its lack thereof, but the Hurwitzes took a more direct approach, reworking each original verse to one that indisputably qualifies as ironic. "It's a black fly in your Chardonnay, that was specifically purchased to repel black flies," goes the rewrite. "It's like rain on your wedding day—a day and place you chose because it's known not to rain."
Eliza and Rachael Hurwitz are two of a set of triplets who remembered hearing an English teacher bemoan the song's lyrics. Eliza, a stand-up comedian who recently graduated from New York University, decided to rewrite the song last year while writing a column for the humor website Hello Giggles.
She enlisted Rachael, a recent Connecticut College graduate who is now pursuing a career in music, to film a spoof with her. The sisters live in New York and began performing comedy together this summer. This was their first comedy video.
"We felt like [a video] would pack the most punch," Eliza said. "We were hoping we'd get a couple hundred views, but then ['Star Trek' actor] George Takei tweeted about it and it just blew up." The sisters said they plan to move away from parody and focus on original content in their next videos.
Ms. Morissette's original song is no stranger to ridicule. Shortly after its debut, Irish comedian Ed Byrne ruthlessly roasted the lyrics in his routine. "The song should have been called 'Unfortunate,' " he ranted. "There's nothing ironic about being stuck in a traffic jam when you're already late for something, not unless you're a town planner."
A decade later, writer Patrick Cassels rewrote a few of the lyrics in a list-style format for College Humor. Mr. Cassels also aimed for real irony—it's like "rain on your wedding day...to Ra, the Egyptian sun god," he wrote.
His post didn't exactly go viral. "The girls bring a lot more to it than I did," he said. "Their version is way more multidimensional."
The Original: 'Ironic' by Alanis Morisette
The Parody: 'It's Finally Ironic' by Eliza and Rachael Hurwitz
Write to Megan Buerger at email@example.com


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After famed Coney Island pizzeria Totonno's reopened last week, the Daily News filed an article celebrating the pizzeria's triumphant return.
But it turns out that they got one very important thing wrong. In the piece, author Mark Morales says that "the tiny pizza shop spent almost $150,000 to replace the oven, refrigerators, air conditioners, electrical wiring and even cash registers."
The oven, which dates back to the pizzeria's founding, thankfully remains intact. Co-owner Antoinette Balazano says that such a loss would have been a tremendous blow to the pizzeria. "The thing is I never said that we replaced the oven but my God that's the original oven and that's very important," she told me.
Indeed, as we reported back in December, the only fixtures that got replaced were the tiles.
Of the rebuilding, Antoinette says, "I'm so happy with the way the store looks—I feel like it went back to the old world look. I never liked the colors after the fire...We're fortunate, we're okay. I have to pay, I don't know if its $150,000 or if it might be more. It looks beautiful, the customers are the finishing touch."
About the author: Chris Crowley is the author of the Bronx Eats column. Follow him on Twitter, if you'd like. In person, your best bet is the window seat at Neerob, or waiting in line at the Lechonera La Piranha trailer.


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Thiamine may cause low blood pressure. Caution is advised in people taking drugs that lower blood pressure.
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Thiamine may also interact with agents that affect the immune system, agents that enhance athletic performance, agents that promote urination, agents that treat retrovirus infections (HIV), agents that widen blood vessels, agents used for heart disorders, alcohol, Alzheimer's agents, antacids, antibiotics, anticancer agents, barbiturates, birth control taken by mouth, dextrose, dichloroacetate, flumazenil, heart rate-regulating agents, ifosfamide, metformin, naloxone, nervous system agents, neuromuscular blocking agents, pain relievers, phenytoin, thyroid hormone, tobacco, and weight loss agents.
Caution is advised when using herbs or supplements that may lower blood sugar. Blood glucose levels may require monitoring, and doses may need adjustment.
Thiamine may cause low blood pressure. Caution is advised in people taking herbs or supplements that lower blood pressure.
Thiamine may also interact with Alzheimer's herbs and supplements, antacids, antibacterials, anticancer herbs and supplements, benfotiamine, betel nuts, birth control taken by mouth, heart rate-regulating herbs and supplements, herbs and supplements that affect the immune system, herbs and supplements that enhance athletic performance, herbs and supplements that promote urination, herbs and supplements that widen blood vessels, herbs and supplements used for heart disorders, horsetail, nervous system herbs and supplements, neuromuscular herbs and supplements, pain relievers, polyphenols, sedatives, thyroid herbs and supplements, tobacco, vitamins, and weight loss herbs and supplements.
Portions of this document last updated: Nov. 01, 2013
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MoneySuperMarket: here to help you get the protection you need
Life insurance is a vital part of financial planning for anyone who has dependents. By 'dependents', we're referring to those whose circumstances and material wellbeing would be affected by your death. So that means your partner, your children or anyone else who is financially reliant on you.
If you have a partner and children, then the two of you should think about life insurance, regardless of whether one or both of you are earning. After all, how would the family cope if the partner who stayed at home were to die? The survivor couldn't just give up work to care for the house and children, so money would be needed to make alternative arrangements.
All this can be a delicate and even difficult topic to think about, which is why many people fail to act. But not doing anything puts their loved ones at grave financial risk. That's why it's crucial to grasp the nettle and get your life insurance – and that of your partner, if you have one – properly sorted out.
How does life insurance work?
Life insurance comes in a variety of forms. At its simplest, it pays out an agreed amount, either as a lump sum or as a regular income, if you die within a specified period – known as the 'term'. Hence its name: term insurance.
You choose the amount to be paid – the 'sum insured' – and you decide the length of the term. But how do you reach your decisions? What factors should you take into account? What are the implications for the size of the premium of each decision you make?
We're here to answer these questions. And help you find the best deal for your circumstances from the UK's leading life insurance providers.
Protection equals peace of mind
Deep down, we all know we have a responsibility to provide for our dependents. It you have a family, it comes with the territory – it's a simple as that.
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That said, if you've got this far, you clearly understand your responsibilities and want to do something about them.
We can help. Our extensive range of guides, listed on the left, will tell you all you need
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If you'd like to read about the various life assurance products available to you, have a look at our life insurance guides in order to learn what the best life insurance policy is for you.
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Alternative Dosing and Regimen of Replagal to Treat Fabry Disease
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- No Study Results Posted
- Disclaimer
- How to Read a Study Record
The main goal of this study is to assess the pharmacodynamic effects of different or more frequent doses of Replagal compared to the standard dosing regimen. Replagal is a genetically engineered form of alpha-Galactosidase A, an enzyme that normally breaks down a fatty substance called globotriaosylceramide (Gb(3)). In patients with Fabry disease, GB(3) does not function properly and therefore builds up causing problems with the kidneys, heart, nerves, and blood vessels.
Male patients 18 years of age or older with Fabry disease who are not on dialysis and have not received a kidney transplant may be eligible for this study.
Participants are randomly assigned to receive one of the following five regimens of Replagal infusions, given through a vein over 20 to 80 minutes:
0.1 mg/kg body weight every week
0.2 mg/kg body weight every week
0.2 mg/kg body weight every other week
0.4 mg/kg body weight every week
0.4 mg/kg body wieght every other week
In the US, the infusions are given at the NIH Clinical Center. Vital signs are measured before, immediately after, and 1 hour after each infusion.
Baseline evaluations are done on an inpatient or outpatient basis. Baseline tests include a check of vital signs (temperature, respiratory rate, pulse rate, and blood pressure); physical examination; laboratory tests; and review of treatment side effects. Evaluations are also done at every infusion visit, and 1 week and 1 month after the last infusion.
Safety evaluations are done periodically and include vital sign measurements, physical examination, blood and urine tests, review of drug side effects, electrocardiogram (ECG), Holder monitor (2 hour ECG), and QSART (NIH only). The QSART (quantitative sudomotor axon reflex test) measures the amount of sweat in a particular area of skin, mostly the forearm. For this test, a cup partly filled with a liquid is strapped on the arm. A weak electric current is turned on, stimulating the sweat glands, and the amount of sweat produced is measured. There is a tingling sensation when the current is turned on.
Patients who complete the study will be offered the opportunity of receiving Replagal for 6 months in an extension study.
|Fabry Disease
|Drug: Replagal
|Phase 2
|Study Type:
|Study Design:
|Primary Purpose: Treatment
|Official Title:
|A Phase I-II Pharmacokinetic/Pharmacodynamic Study of Replagal to Assess the Effects of Alternative Dose and Regimen in Patients With Fabry Disease
|Estimated Enrollment:
|Study Start Date:
|January 2004
|Estimated Study Completion Date:
|November 2005
OBJECTIVES: The goal of this study is to assess the pharmacodynamic effects of alternative weekly and every two week dosing regimens of Replagal (agalsidase alfa) in comparison to the current standard Replagal treatment regimen of 0.2 mg/kg given intravenously every two weeks.
STUDY POPULATION: Hemizygous males with Fabry disease who are 18 years of age or older.
DESIGN: This is a randomized, open-label study that will assess the pharmacodynamics and pharmacokinetics of five different dosing regimens of enzyme replacement therapy with Replagal. The effects of dose as well as dosing frequency will be evaluated and compared to the standard Replagal regimen.
OUTCOME MEASURES: The pharmacodynamic parameter to be assessed is plasma globotriaosylceramide (Gb3). The hypothesis to be tested is the role that frequency (weekly) and/or dose (0.1 to 0.4 mg/kg) of Replagal will play in pharmacodynamics as measured by reductions in plasma Gb3 compared to the current dose and frequency of 0.2 mg/kg given every two weeks. Clinical parameters including sweating, heart rate variability, proteinuria, severity of neuropathic pain, pain and anti-diarrheal medication usage, frequency and severity of abdominal pain, and frequency of diarrhea also will be assessed.
|Ages Eligible for Study:
|Child, Adult, Senior
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Subject is a male hemizygote, age 18 years or older, with confirmed diagnosis of Fabry Disease. Diagnosis of Fabry disease may be confirmed by proof of a mutation of the alpha-Galactosidase A gene compatible with Fabry Disease and/or a deficiency of alpha-Galactosidase A (less than 4.0 nmol/mL/hour in plasma or serum or less than 8% of average mean normal in leukocytes).
Subject must have one or more clinical manifestations of Fabry disease including neuropathic pain, angiokeratoma, corneal verticillata, cardiomyopathy, hypo- or anhydrosis, abdominal pain and/or diarrhea, serum creatinine greater than 1.0 mg/dl or proteinuria greater than 300 mg/24 hours.
Subject must have voluntarily signed an Institutional Review Board (IRB) approved informed consent form after all relevant aspects of the study have been explained and discussed with the subject.
Subject has been previously treated with Replagal or any other enzyme replacement therapy for Fabry Disease. If the patient has previously been treated with Replagal or another enzyme replacement therapy then they must have been off the therapy for at least 30 days and must have a Day-14 antibody blood sample drawn and that test must be negative for anti-agalsidase alfa IgG and IgE antibodies and not experienced a prior severe infusion reactions with prior enzyme replacement therapy.
Subject has been enrolled in another clinical investigative study in the past 30 days.
Subject is unable to give informed consent or is deemed unable to comply with all aspects of the clinical trial.
Subject has plasma Gb(3) drawn on Day -14 less than 4.0 nmol/mL.
Subject is undergoing dialysis or who has received a renal transplant.
Subjects who cannot tolerate the study procedures or who are unable or unwilling to travel to the study center as required by this protocol.
Subjects with an inter-current medical condition that would render them unsuitable for the study (e.g. HIV, diabetes) by confounding an assessment of the effects of the experimental therapy and its adverse events.
Subjects who in the opinion of the investigator (for whatever reason) are thought to be unsuitable for the study.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00075244
|United States, Maryland
|National Institute of Neurological Disorders and Stroke (NINDS)
|Bethesda, Maryland, United States, 20892
|ClinicalTrials.gov Identifier:
|NCT00075244 History of Changes
|Other Study ID Numbers:
|Study First Received:
|January 6, 2004
|Last Updated:
|March 3, 2008
Keywords provided by National Institutes of Health Clinical Center (CC):
Fabry Disease
Additional relevant MeSH terms:
Fabry Disease
Lysosomal Storage Diseases, Nervous System
Brain Diseases, Metabolic, Inborn
Brain Diseases, Metabolic
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Cerebral Small Vessel Diseases
Cerebrovascular Disorders
Vascular Diseases
Cardiovascular Diseases
Genetic Diseases, X-Linked
Genetic Diseases, Inborn
Lysosomal Storage Diseases
Metabolic Diseases
Lipid Metabolism Disorders
Metabolism, Inborn Errors
Lipid Metabolism, Inborn Errors
ClinicalTrials.gov processed this record on September 21, 2017


text:
Iwakuma battles effects of heat against A's
PHOENIX -- Hisashi Iwakuma wasn't his normal ground-ball-inducing self on Monday, but the veteran right-hander battled his way through a spring-high five innings, and the Mariners held off the A's for a 6-5 win in Cactus League action at Phoenix Municipal Stadium.
Iwakuma gave up six hits and three runs, including a two-run blast by catcher Derek Norris in the fourth inning. The 31-year-old wasn't as sharp as he'd been in previous outings, having allowed just seven hits and three runs in 10 prior innings.
After not walking a batter all spring, he issued two free passes and recorded no strikeouts, but he said there was a reason for that, as the 83-degree heat caused him some issues with the ball.
"My pitches were a little higher than I expected, especially the fastball," Iwakuma said through interpreter Daisuke Sekiba. "The air was kind of dry, and the ball felt a little slippery. So I tried to pitch lower, like last time, but I didn't have good command with it. I was losing my grip."
Iwakuma's sinker normally induces numerous ground balls, but an uncharacteristic 10 of his outs came on fly balls, compared with four on the ground, and the A's cranked out three doubles in addition to Norris' home run.
Manager Eric Wedge saw no reason for concern, however, as Iwakuma continued working his way through a long spring.
"I thought he threw the ball well," Wedge said. "He was up a little bit later, but he did a good job putting the ball on the ground when he needed to, and he used all his pitches. He continues to be strong. It was another good day for Kuma."
Iwakuma is on schedule to pitch the second game of the regular season, against the A's on April 2. His Cactus League ERA stands at 3.60 with two starts remaining.
Greg Johns is a reporter for MLB.com. Follow him on Twitter @GregJohnsMLB as well as his Mariners Musings blog. This story was not subject to the approval of Major League Baseball or its clubs.


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Crisp to miss several days with neck strain
ANAHEIM -- A's outfielder Coco Crisp was missing from Sunday's lineup for a second consecutive game because of a neck strain and will remain out "a few days," according to manager Bob Melvin.
Like he did at the beginning of the month, Crisp could potentially receive several trigger point injections to help treat the neck issue once the club returns home. No matter the length of his recovery, he won't need to go on the disabled list with 25-man rosters expanding Monday.
Crisp aggravated his neck while making a stellar effort to rob the Angels' Chris Iannetta of a homer in Friday's game.
Sam Fuld and Craig Gentry will continue to alternate in center field in his stead.
Jane Lee is a reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.


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Honestly I've never heard of this person
What genre of music does she sing?
Artists like this are rare these days. All too often we get whatever the Disney channel or Nickelodeon throws at us. This woman genuinely has talent, isn't necessarily the sexiest person I have ever seen (sorry, it's true), but is selling albums because she can actually sing, unlike most everyone else out there.
Adele rox......................Love her style of music.
Overrated! It's all about blink 182 but at least she's better then ugly c-low green & Lil Wayne damn ugly talentless monkeys & not bein racist they actually do look like ugly monkeys no joke. O.e


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As the Northeast Ohio Medical University moved through a critical phase of its construction process, it was time for the NEOMED community to make their mark on the newest building on the Rootstown campus.
The last piece of steel on the Research and Graduate Education building will be placed today, and on Friday that beam was placed on a walkway, where students, faculty and the community were invited to sign it.
While most used provided markers to simply sign their names, others left tributes to be permanently imbedded in the structure.
One such tribute was left by a member of the "class of ... I'm gonna be here forever."
"Second MD/PHD," the student wrote. "This building will be my home."
Dr. William Horton, dean of the college of graduate studies and vice president of research, left his own signature on the beam, writing, "One small beam for the building, one giant step for NEOMED."
He said the building is expected to open in May, and this weekend, the last of the steel framing will be done. The beam signing, he said, was open to anyone who happened to be on campus that day, including faculty, students and any residents who wanted to sign.
"We really wanted them to be part of this," he said.
Nearby stood a sample column, featuring the brick that will be used on the exterior of the structure so visitors can see its similarities, and its differences, from the building that will stand next door.
"We wanted to have it within the context of our existing, campus, but we also wanted to make it more modern and add more glass," he said. "I think it's going to be beautiful."
The structure will house 20 existing scientists, as well as 10 more being recruited to work on the campus, and will house all of NEOMED's graduate education classrooms, lecture halls and offices.
The existing space on the campus will be renovated to house the "Redizone" that will include 10 commercial businesses that have partnered with NEOMED. It also will temporarily house the Bio-Med Science Academy, prompting one student of the academy to write, "Finish this building. Start the school."
To the north of construction, work in progressing on the residential housing village. A mock-up of the buildings, featuring the same furniture and layout that will be available in the new apartments, is under construction and is expected to be available for students to visit in the weeks ahead. The housing village will be completed in August.
Land also is being cleared at the front of the campus for the Health and Wellness center.
All told, the buildings will cost about $130 million.
Dr. Charles Taylor, the new dean of pharmacy at NEOMED, also was among those signing the beam and observing the construction. The Department of Pharmaceutical Sciences will be located in the Research and Graduate Education building once it is complete.
"We're looking forward to the opportunity to discover new medications, and improve upon the ones we have," he said.
Contact this reporter at 330-298-1139
or email@example.com


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Ali Carter is planning to return to snooker in October at a low-profile tournament in Bulgaria.
The 35-year-old Essex cueman has been undergoing chemotherapy after being diagnosed with lung cancer in May.
Carter, the two-time former World Championship finalist, intends to be back in action at the European Tour Players Tour Championship event in Sofia, which runs from October 3-5.
Carter wrote on Twitter late on Wednesday night: " I have entered my first tournament today, the PTC in Bulgaria!!"
He is battling cancer for a second time, after being cured of testicular cancer last year.
Carter has finished his course of chemotherapy for the lung condition.
He added on the social network: "H opefully got my last treatment next week, which is radio frequency ablation to burn the remaining tumour away! Then I will be brand new.
"So #watchoutworld I have nothing to be afraid of anymore! And nothing I can't achieve..#beatingcancer #forthesecondtime"
Carter lost to Ronnie O'Sullivan in his two Crucible finals, in 2008 and 2012, and is a former winner of the Welsh Open, Shanghai Masters and German Masters.


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This wind- and weather-resistant, reusable, EPA-accepted pesticide sign is constructed of heavier, 4-mil horizontal-fluted plastic with the correct legend and legend size. Pesticide sign measures 14"W x 16"H. Pesticide sign reads in both English and Spanish. USA made.
NOTE: This sign does not meet California WPS requirements. California WPS sign is Item No. D1212.View All Warning Signs
2017 Reference Guide: Page 122


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Marketing Information
Data center managers must provide faster data storage and access without incurring data corruption or loss. They must also achieve this while juggling tight IT budgets and managing highly complex system environments. Designed for the enterprise, the Pulsar.2 drive is the first MLC-enabled SSD from an enterprise storage company to deliver the price-performance benefits with the data integrity and drive endurance needed for demanding enterprise environments.
General Information
|Product Type
|Solid State Drive
|Manufacturer Part Number
|Manufacturer Website Address
|Seagate Technology
|Product Model
|Product Name
|Pulsar.2 ST400FM0012 MLC Solid State Drive
|Product Line
|Brand Name
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|Drive Interface
Physical Characteristics
|Form Factor
|Compatible Drive Bay Width
This product is shipped only within Canada and Warranty valid for Canada only.
Computer Valley makes every effort to provide accurate specifications, descriptions, images and price on all products that are found on www.computervalley.ca
However for complete and updated descriptions, compatibilities, specifications and actual photo we recommend our clients to consult with manufacturer's websites or simply call us for proper clarifications. Computer Valley is not responsible and will not accept returns for items purchased that are not compatible with your system. Please ensure that you have verified compatibility and actual photo with your system by visiting the manufacturer's web site prior to purchase or give us a call to make sure what you are purchasing.
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We ship by UPS, FEDEX, USPS, CANADA POST , PUROLATOR and LOOMIS from the nearest locations possible based on stock in hand.
Please note: Computer Valley reserves the rights to accept and cancel any order at anytime due to pricing error or any other reason. An email will be sent as a confirmation of the order status.
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Samsung Galaxy S4 costs $235 to make
Samsung's Galaxy S4, a bigger and faster smartphone unveiled last week, costs $US244 ($A235) to make, according to data from market researcher IHS iSuppli.
A larger and more-advanced display, faster chip and more computer memory drove the cost of building the entry-level 16 GB Galaxy S4 15 per cent higher than its predecessor, the Galaxy S3, the researcher said.
The handset, which has a 5-inch screen and 13-megapixel camera, is among three high-end smartphones Samsung will release this year after being overtaken in the US by Apple's iPhone 5 in the fourth quarter. The materials and manufacturing cost of the iPhone 5 is $US207 ($A200), iSuppli said in September, just after it debuted.
"Although its hardware is not radically different from the Galaxy S3 introduced in April of 2012, the Samsung Galaxy S4 includes some critical component updates that enhance its functionality," said Vincent Leung, senior analyst for cost benchmarking at IHS iSuppli.
The estimates are based on a "virtual teardown" and may be amended after a physical examination of the device and its components, the researcher said.
The new model will be available in the US from April 26, and in Australia shortly thereafter.
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So far, 2010 is looking like a great year for indie and alternative rock.
Browse playlist mixes with hundreds of free, legal MP3s.
New Posts and PlaylistsFavorite Indie and Alternative Songs of 2009, Vol....
Best New Releases This Week: Beach House, The Magn...
Band of the Week: Boston's Elephantom Endorsed by ...
Best Rarely Heard Songs of 2009, Vol. II - Ex Norw...
Favorite Indie and Alternative Songs of 2009, Vol....
In Dee Mail Special Edition Vol. VII - Essex Chane...
Favorite Indie and Alternative Songs of 2009, Vol....
Best New Releases This Week: Spoon, Surfer Blood, ...
Favorite Indie and Alternative Songs of 2009, Vol....
One Man Bands - LA's Fox Fagan and Detroit's Jelly...
best indie albums 2008
Latest Tweets
The Middle East are an Australian band that have really turned on the turbo engines in the past year or so, landing scheduled shows at this year's SXSW and Coachella, and are an IRC Band to Watch in 2010 thanks to the release of their EP, The Recordings of the Middle East last fall. Thankfully, they sent us two fantastic songs from the EP to share with all of you.
"Blood" - The Middle East from The Recordings of the Middle East (2009)
"The Darkest Side" - The Middle East from The Recordings of the Middle East (2009)
The Middle East official website
The Love X Nowhere - High Score Blackout
The Love X (as in "times") Nowhere's latest LP, High Score Blackout, was released last summer on Redgummy Records. The album oozes with Cocteau-heavy guitars dripping with the sway of chorus and delay; analog synth as at home with The Cars as Meddle-era Pink Floyd; a rhythm section adept in thick, explosive grooves and awe-inspiring dynamics.
"The Diz" - The Love X Nowhere from High Score Blackout (2009)
The Love X Nowhere
Emanuel and the Fear - Self-Titled EP
Brooklyn's 11-piece band Emanuel and the Fear, released a self-titled debut EP late in 2009 to enthusiastic reviews in publications like the Village Voice, Deli Magazine, Absolute Punk and NME. Headed by NYC resident Emanuel Ayvas, EATF creates and delivers magnificently crafted, and complex, yet accessible songs. Their self-titled debut EP was released last January on Paper Garden Records and included contributions from musicians who have previously played and toured with Sufjan Stevens, The National, Akron/Family and Bryan Scary & The Shredding Tears.
"The Rain Becomes the Clouds" - Emanuel and the Fear from s/t EP (2009)
"Comfortable Prison" - Emanuel and the Fear from s/t EP (2009)
Emanuel and the Fear on MySpace
Solfege Radio - Eleven!
New Jersey's melodic pop punk band Solfege Radio released their debut album late in 2009 on Danimal Records to fairly good press and reception from fans. The band of teen musicians demonstrate a true talent at a young age for crafting tight rock songs with a shimmering undertow. We'd be curious to know what you think about this single.
"Eleven!" - Solfege Radio from s/t debut (2009)
Solfege Radio on MySpace
Jacob Faurholt - Why Write
In December, we featured Danish musician Jacob Faurholt in the In Dee Mail Special Edition, Vol. I, post. Now, Faurholt has another song to share, "Jesus on a Stamp," which sounds like the Editors mixed with Interpol, accompanied by bright keys and booming drums, hand-clapping and flowing choruses.
"Jesus on a Stamp" - Jacob Faurholt from Why Write EP (2009)
Jacob Faurholt on MySpace
Franklin for Short - Swell
Franklin for Short hails from Ventura, California, a quiet little beach town 75 miles north of L.A. Living off a diet of burritos, coastal fog and reverb, the band has been incubating their latest release Swell for a year and a half. The result is a 14-song epic that winds its way through a landscape half ethereal and half earthbound.
"Brother Bird" - Franklin for Short from Swell (2009)
Franklin for Short on MySpace
Other songs from In Dee Mail:
"Everything" - Adam Ashbach from Puzzle Pieces (2009)
Adam Ashbach on MySpace
"Tired of Missing You" - Andrea Gauster from Reverie EP (2009)
Andrea Gauster on MySpace
"Beasts Around You" - Idolae from Through The Straight Lines (2009)
Idolae on MySpace
"Soft" - Capybara from Try Brother (2009)
Capybara on MySpace
You Might Also Be Interested in These Posts:
Best New Releases This Week: Beach House, The Magnetic Fields, No Through Road, Woodpigeon, Retribution Gospel Choir, Citay, Boy Genius & More
Band of the Week: Boston's Elephantom Endorsed by Grizzly Bear; Blog Exclusive of Track for Upcoming LP
Best Rarely Heard Songs of 2009, Vol. I - Ex Norwegian, We All Have Hooks for Hands, Pistol for Ringo and Fredrik
Best New Releases This Week (1/19/10): Spoon, Surfer Blood, The Eels, Feral Children, Editors, Big Star, Dinowalrus & Len Price 3
Favorite Indie and Alternative Songs of 2009, Vol. III: Neko Case, Public Radio, Bishop Allen, Harlem Shakes, Deer Tick & More
In Dee Mail Special Edition Vol. VII - Essex Chanel, Scares The Daylights and The Binary Marketing Show
Favorite Indie and Alternative Songs of 2009, Vol. II - The Big Pink, The Thermals, Dan Auerbach, Telekinesis, Faunts & More
Labels: Emanuel and the Fear, In Dee Mail, The Love X Nowhere, The Middle East
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2 Comments:
- At 9:17 PM , Nia said...
Broken Bells is an amazing group with a great sound!!!!!!!!
If you haven't heard about 'Broken Bells' you are missing out. The groups video premiered on myspace 1/27 if you missed it check it out by clicking the link below.......
'Broken Bells' album will be released 3/09, but you can pre-order your deluxe edition of the album by clicking the link below........
- At 12:27 AM , said...
Jacob Faurholt is Danish and leave in Germany.
Your site is very nice by the way ^^
Great Job!!!


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Results 1 to 5 of 46
Thread: "A Cupcake Shop" Name Game
Threaded View
August 14th, 2013 03:26 PM #75
Your name is Arabella Primrose Keifer. You recently graduated college studying art. You're living in a small apartment in Brooklyn, New York. You are working as a cashier in a nearby bakery, and you love your job. You love smelling cookies baking when you walk in, you love the little kids messing their faces with cupcakes, and you've taken notice of the new baker, Nicholas Andrew Paxton. One day, just as you are leaving, this new baker stops you. He says that he bought two tickets to go to "Peter Pan" at the theatre, and his friend can't go. He asks you if you wanted to go with him. Smiling, you accept and immediately race home to decide what to wear. You wear: Coral for One Dress | Mod Retro Vintage Solid Dresses | ModCloth.com
You go, and you both have a wonderful time. You go home feeling dazed and delighted. It isn't long before you are both in love with each other. After two months, he proposes to you, by creating a special cupcake. The cupcake has a red heart on it and your initials piped on, and on top, is your ring. Of course, you accept, and begin to plan your wedding! Your ring looks like: Official Cartier websites & online stores - The renowned French jeweler and fine watchmaker. Bridal, Luxury Accessories, Fragrances & Exceptional Gifts
What kind of wedding do you have, and what dress?
Chic and modern in a city loft. DRESS: Satin Faced Organza Fit and Flare Gown - David's Bridal
After the wedding, you move into his small home on the outskirts of the city you lived in before. His house looks like: Small Brick House - Stock Photo - iStock
After five months with him, you decide your home is lonely, and needs children. You become pregnant! Your husband is extremely happy, and both of you can't wait to become parents. You decide you don't want to know the gender, you want it to be a surprise. You redecorate the study of your home, and it becomes a nursery for your little one. How do you decorate it? Reese | Pottery Barn Kids
Nine months later, you have give birth to a wonderful healthy boy! You decide the middle name will be Peter, after "Peter Pan."
DS: Wylie Peter Paxt0n
When your baby is two, you and your husband open your own cupcake shop in the city, Neverland Cupcakes. He bakes, you decorate, and you've hired a few people to help out. It thrives, and you add in a kids playroom in the shop, so that you can watch your son while you work. Everything is working out nicely. Four years after your shop opens, you decide your son needs a sibling. You become pregnant again! This time, you decide to find out the gender, and realize you have twin girls! Your son is very excited to have sisters! But now that you are going to have a family of five, your house is much too small. You buy a new one closer to your shop. What does it look like? "Painted Lady" style home - Stock Photo - iStock
Four months after you've moved into your house, you give birth to two beautiful baby girls.
DD/DD: Ellery Delphine Paxton/Emery Dahlia Paxton
Now, you have a charming old home, a quaint but thriving cupcake shop, and three beautiful children, who make you smile each day. Then suddenly, four years later in a nearby city, there is an earth quake. Your very good friends pass away, but miraculously their newborn baby girl was found alive in all the rubble. When their will is read, you are shocked to find that you and your husband are the next in line to take care of this child. Tearing, you bring her home to your family. You decide to rename her middle name "Miracle". And her first name, given by her biological
parents, Charlotte. Your children immediately love her, and she is quickly a perfect part of your family.
DD:Charlotte Miracle Paxton
You have quite a busy life, with four children and your own business. You work hard to get your kids to and from activities. You bustle around in your shop, always greeting customers and trying to maintain it's status in the city as the "most lovely little bakery with a cheerful staff". One Friday night, your husband surprises you with a weekend getaway! He has already planned everything out, and you leave for your flight. Where do you go?
While there, you become pregnant! You are very excited, as is your family. You wait for the gender to be a surprise! Nine months later, you give birth to a handsome, healthy baby boy. You decide his middle name should honor his father. His name is Bram Nicholas Paxton.
You decide five children, a self-run business and a loving husband is enough.
Nicholas and Arabella
Wylie, Ellery, Emery, Charlotte and BramTeresa
Favorite names:Arabella Primrose,Charlotte Madeline,Atticus Fletcher, Tobias Jackson


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A MONTH of arts, entertainment and celebration began yesterday (Friday, August 1) as the annual Ilkley Summer Festival got underway.
Starting with Yorkshire Day festivities, the festival is back in town once again this year and offering all kinds of music, entertainment and treats for both townspeople and visitors to Ilkley.
As always, the festival began with the Yorkshire Day festivities - this year with the declaration being made at the bandstand on The Grove.
Bigger events and concerts are taking place every weekend, and highlights this year include a studio theatre being set up on The Grove, as well as the return of favourites such as the continental street market on The Grove.
Other events include the cricket school taking part at Ben Rhydding Cricket Club next week, and Heritage Guided Walks taking place throughout the month.
Also coming up this week will be This Concert Needs You - a nostalgic concert of music popular in 1914, on the eve of the outbreak of the First World War. This will take place at St Margaret's Church, Queens Road, on Saturday, starting at 7.30pm.
The continental street market will be back on The Grove from August 8-10.
The Dolce Vita cabaret weekend will see Dominic Halpin and the Honey Bs return to The Grove for a concert on August 16, supported by the Tre Tenori, The following day, family fun and sparkling entertainment will be on offer in the form of top tribute band Take That 2, and Robbie
Festival director, Anne Hawkesworth, said: "Last years matinee with Abba Revival was such a huge success that it was decided to repeat the event with Take That 2 plus Robbie. It will be another "family friendly" afternoon with family tickets available. Also on the bill will be local support act 5 Dollar Shoes. They will be kicking off at 2pm, giving all the opportunity to have their picnics and get into the mood."
From August 22 to 25, the studio theatre on The Grove will play host to musicians playing a variety of genres.
Nostalgic music from the past will lead up to a 60s night featuring The Pepper Hearts on August 22. August 23 will be a folk day, with Houghton Weavers performing in the evening.
Sunday will be international day, featuring Hindi drummers, Flamenco and Latin American music, before Dominic Halpin takes to the stage for his second performance of this year's festival, with country, rockabilly and rock 'n' roll band The Hurricanes.
Bank Holiday Monday, August 25, will be jazz day at the studio theatre.
Acts include Ben Lowman Django Project, New York Brass Band - New Orleans-inspired music from the mean streets of York - and Beverley Beirne's Stripey Animals, playing tunes from a mixture of genres that they interpret into the jazz idiom, and originals.
A full day ticket costs £10.
The festival finale will the Ilkley Parish Council-organised Concert on The Grove, featuring Last Night of the Proms style favourites.
For full information on festival events, and to book tickets, visit Ilkley Visitor Information Centre, Ilkley Town Hall, or call (01943) 602319.


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3 cups All-Purpose flour
1/4 cup sugar
1 1/2 teaspoons salt
10 ounces unsalted butter, cold, cut into small chunks
3 ounces lard, cold, cut into small chunks
1/2 cup ice water
For the filling:
2 pounds apples, peeled, cored and cut into chunks
1 cup sugar
1/2 cup honey
1/3 cup cornstarch
1 teaspoon vanilla extract
1/4 teaspoon cinnamon
Zest and juice of 1 lemon
For the egg wash:
1 egg
1 teaspoon salt
Sugar, for sprinkling
To make the crust, in a food processor pulse together the flour, sugar and salt. Add the butter and lard, then pulse briefly until the mixture forms small crumbs. Add the ice water and pulse just until a dough forms. Divide the dough into 2 pieces and shape into discs. Wrap each disc in plastic wrap and refrigerate at least 1 hour or overnight.
When chilled, to prepare the pie shell, on a floured surface roll out one disc to a 14-inch circle using a rolling pin. Transfer the dough to a lightly greased, deep 9-inch pie pan, leaving a 1 inch overhang. Refrigerate the crust in the pan for at least 30 minutes or overnight.
When ready to bake the bottom crust, heat the oven to 375 F. Line the cold crust with foil and fill with baking weights, rice or dry beans to hold it in place. Bake the pie shell for 30 minutes and remove from oven. Leave the oven on once the crust is done.
While the crust is baking, prepare the filling. In a large saucepan, toss together the apples, sugar, honey, cornstarch, vanilla, cinnamon and lemon zest and juice. Let sit for 20 minutes.
Bring the fruit mixture to a boil over medium heat. Cook, stirring occasionally to prevent sticking, until the fruit thickens. Let cool.
When the bottom the filling has cooled, pour the it into the baked crust. Roll out the second disc of dough to about 12 inches.
In a small bowl, beat the egg with the salt. Use a pastry brush to brush the egg on the edges of the cooked crust. Place the top crust over the filling. Using a fork or crimper, gently crimp the top crust, sealing the pie around the edges.
Slit the top of the crust with a paring knife in several places to create steam vents. Brush egg wash over the crust, then sprinkle with sugar. Bake for another 30 to 40 minutes, or until the filling is bubbling and the top crust is golden brown. Let cool for 1 to 2 hours before serving.
Servings: 8
American Guest House Bed and Breakfast
Washington DC Bed and Breakfast accommodations. We are centrally located, 10 minutes walk to DuPont Circle metro/subway, 1 mile north west of White House.


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Queen Victoria
4 out of 5 stars
Download the FREE app and meet your ship mates!
Read the best port reviews and tips for this cruise itinerary.
|Day 1
|Southampton (London), England
|Day 2
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|Day 3
|Hamburg, Germany
|Day 4
|At Sea
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|Copenhagen, Denmark
|Day 6
|At Sea
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|Day 8
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|Day 9
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|St. Petersburg, Russian Federation
|Day 11
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|Kiel, Germany
|Day 13
|Goteborg (Gothenburg), Sweden
|Day 14
|At Sea
|Day 15
|Southampton (London), England
A roll call is a space for members who are signed up for the same cruise (same ship & departure date) to connect.
Make friends BEFORE you sail, exchange tips on what to do onboard and in the ports and maybe even organize a shore excursion with your ship mates.


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A high performance and safe auger perfect for professionals.
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