text:
Browse Como.gov Skip top Navigation. Translate this page
The City of Columbia offers two programs utility customers can sign up for to provide assistance for some customers who have difficulty paying their utility bill. Donations to each program are kept separate. Every dollar goes to help someone in need. A simple donation of $1 or more per month will assist those in need to pay utility bills in one-time emergency situations.
C.A.S.H. (Citizens Assisting Seniors and Handicapped) – Specifically assists low income elderly and low income disabled citizens who have exhausted other resources.
H.E.L.P. (Heat Energy and Light Program) – Provides aid to low-income families with children in one-time emergency situations.
Special envelopes are provided to utility customers once a year in November to sign up for this program. However, customers may sign up to participate in these programs at any time during the year by completing an online C.A.S.H. and H.E.L.P Pledge Form.
If you prefer, you may print the C.A.S.H. and H.E.L.P Pledge Form and return it with your bill payment or send it to Utility Customer Services. Please indicate if it is a monthly pledge or a one-time donation and the pledge amount.
The form will be in effect until the customer notifies Utility Customer Services to be removed from the program.
Year-to-date contribution will be stated on your February bill for tax records.


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We're #1.
Copycats. ed:
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We're #1.
Copycats. ed:
Your just on an a-hole roll today, aren't you?I know!!!!! You should start the 3rd thread today with this!!!!!!!!
Sorry. SOME of us have to work for a living and didn't have time yet to peruse the entire forum. ed:I know!!!!! You should start the 3rd thread today with this!!!!!!!!
*shrugs* Just have felt a lot of negativity from you lately. Whatever.
I locked it.I didn't lock it. But you can come to the party if you want.Jerk. ed:TIME FOR A SEXY PARTY!!!!!!!!!!
And apparently, only admins are invited to this party.

subset: commoncrawl


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iHerb お客様のレビュー
NuNaturals, LevelRight
iHerbのお客様により 7 16, 2008 に掲載 | 認証済の購入
My husband takes this product since over 2 years, he is diabetic type 2. LevelRight keeps his blood sugar low. By taking LevelRight everyday he was able to reduce his medicament from 4 pills per day to half a pill per day.
helps with blood sugar spikes for healthy folks too!
iHerbのお客様により 1 03, 2011 に掲載 | 認証済の購入
I don't have any issues with diabetes or a sugar addiction. However, due to my irregular work schedule and when traveling, I sometimes have to delay meals and get lightheaded. Usually after eating, my blood sugar spikes, and all I want to do is take a nap. Not anymore with these pills! I carry a few with me always, making sure to pop one (or two) of these pills about 10-30 min before eating to help not get sleepy. It has also helped when I know I will have a larger meal, which would otherwise leave me in a food coma. It also seems to prevent the continuous blood sugar spikes when eating a sugary treat that usually leaves you craving for more a bit later.
iHerbのお客様により 12 17, 2006 に掲載 | 認証済の購入
I take LevelRight 3 times a day, along with Gluco-Science by Source Naturals, to control my addiction/cravings for sugar, and to help maintain normal Blood Glucose/sugar levels. It has helped me significantly, and I highly recommend it!
really helps me
iHerbのお客様により 11 02, 2008 に掲載 | 認証済の購入
I'm impressed with this LevelRight. Am diet-controlled nearly-diabetic and if I take this with a meal that I know will spike my blood sugar, it goes up much less.
iHerbのお客様により 11 17, 2007 に掲載 | 認証済の購入
I don't have outright diabetes but my blood sugar runs a bit high. This combination of herbal extracts keeps my blood sugar within the normal range. The herbs involved have been used for centuries to control blood sugar, and they really seem to work, at least for me.
See Below
iHerbのお客様により 9 21, 2009 に掲載 | 認証済の購入
Works good with Bitter Melon
Keeps blood sugar stable along with decrease in carbs
iHerbのお客様により 8 01, 2009 に掲載 | 認証済の購入
If you want to follow a low carb diet to keep your blood glucose in the normal range without other medication, this product works.
Nice product
iHerbのお客様により 2 01, 2009 に掲載 | 認証済の購入
Works just fine, helps keep blood sugar levels stable.
NuNatural levelright
iHerbのお客様により 12 27, 2008 に掲載 | 認証済の購入
I got this for a friend who is hypoglycemic and was having trouble with really low sugars. To solve it she ate lots of sweets and had a huge weight gain. This product balanced the sugar and allows her to slow down on the carbs. She does fine now (also switched to 4 small meals the Atkins way.)
A must have
iHerbのお客様により 4 30, 2008 に掲載 | 認証済の購入
I've been using this product for almost 1 year and seen amazing results.


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Last night I finished a remix for 80s Belgian EBM band Absolute Body Control. The lead singer is Dirk Ivens from The Klinik and also Dive. The keyboardist Eric Van Wonterghem can be found today in several projects including Detune-X. Most of the music they recorded together was over two decades ago and they recently got back together to re-release material and perform at some of the huge festivals in Germany such as Wave Gotik Treffen.
The song I was asked to remix was Neverseen. It usually takes me about a full week to do a remix but Eric was on a deadline and I was able to get this done in four long days. The original song was recorded on a 4-track. I was given the vocals and the full song.
One key part of the remix is when I combine my Yamaha CS-5 and a clip of the vocals in Ableton Simpler with the start time automated and have them micro-tune against each other. You can click the screenshot above to see my Ableton screen in full size.
Here is a clip of the original song:
The Horrorist remix of Neverseen:
Look for an interview with Eric from "ABC" in the upcoming issue of Sonic Seducer Magazine. I also answered a few questions in the same interview explaining how I met Eric and how the remix came to be.


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Medical Assistance is a state and federally funded program providing medical coverage for individuals who meet certain eligibility guidelines. If you are eligible, Medical Assistance acts as your insurance company and pays for the cost of medically necessary services such as visits to the doctor, hospital, dentist, specialist, etc. These services are subject to cost-sharing by the enrolled individuals and are authorized and limited by South Dakota Administrative Rule.
Whether or not you qualify, depends on your income and circumstances. For more information, visit your local office.
If you have questions about covered services, contact your medical provider or the South Dakota Medical Assistance Program at 1.800.597.1603. You can also send an email to email@example.com.
SD MEDX provides up-to-date information about recipient eligibility and claims, as well as current physicians and other medical providers in an online directory that recipients can access.
Before seeing a provider, you will need to confirm the provider is a South Dakota Medicaid provider. When making the first contact with the provider by phone, simply ask if they accept South Dakota Medicaid. If they do, you can schedule an appointment.
If you are required to participate in the Managed Care Program, the Department of Social Services will notify you in writing that you need to choose a Primary Care Provider (PCP). A PCP is a physician or clinic who you see for most of your medical care.
DSS will give you a selection form and a list of PCPs in your area. You need to complete the form by choosing a PCP for each eligible member of your family. View a list of PCPs on the SD MEDX Portal via the Provider Locator.
If you are required to participate in Managed Care and you do not choose a PCP, DSS will choose one for you. Contact us at 1.800.597.1603 if you have questions. Save time by selecting your PCP online.
Your chosen or assigned PCP becomes effective the first day of the month after you select or are assigned a PCP. DSS will notify you with the name of your PCP and the date your enrollment begins. You must receive most of your medical care from your PCP in order to have Medicaid assist with paying for it. However, your PCP may refer you to other providers when appropriate.
Please consider the following when choosing a PCP for you and your family:
You can change your PCP in several different ways:
If you are in Managed Care, a referral is required from your PCP or designated covering provider prior to receiving services from another provider, even if it is a specialist or a hospital service (including any non-emergent ER service), acute/urgent care visits or other designated services. View the recipient handbook for more services that would require a referral. A referral can be made by your PCP via telephone referral, physician order, prescription, referral card, or certificate of medical necessity.
No. A proper referral can be provided in many ways, i.e. a telephone referral, a physician order, a prescription, a certificate of medical necessity, etc. As long as the referral mechanism used provides the "referred to" medical provider with the Managed Care necessary information to process the claim as indicated on a referral card (PCP name and #, length of referral, type of service to be provided, date, recipient name).
The referral card is simply a tool indicating the required information needed by the "referred to" provider.
Contact your Benefits Specialist at your local DSS office or call 1-800-597-1603 with your child's Medicaid ID number. In the future, you will be able to access this information by logging into SD MEDX.
When you have a serious health problem that could cause lasting injury or death, you can receive care at the emergency room (ER) and Medicaid will assist with payment.
Examples requiring ER care:
If a medical problem arises that may not be an emergency and you are not sure what to do, call your PCP or on-call provider if it is after hours. If the PCP or on-call provider contacts the ER and refers you prior to a non-emergent service, Medicaid will assist with the payment of these services.
If you go to the ER for a non-referred, non-emergent service, you will be responsible for payment of these services.
If you did not obtain a prior referral to go to your PCP and the visit is not determined to be an emergency by ER staff, you may be billed for the services. Only emergent visits to the ER are covered by South Dakota Medicaid without a PCP referral.
There are many reasons you may be receiving a bill. Some common issues include:
For specific information, you may request a user ID or login to SD MEDX otherwise, please feel free to contact us.
You may be eligible for dental benefits under your South Dakota Medical Assistance coverage. South Dakota Medical Assistance includes many dental services for adults and children. If you are 21 or older, dental services that are not emergency services are limited to a total of $1,000 for the State fiscal year, July 1 to June 30.
Covered Preventive/Restorative Treatments include:
South Dakota Medical Services does NOT cover orthodontics for adults. Orthodontic treatment is a benefit only for children in limited, medically-necessary circumstances.
Visit Insure Kids Now and click on the Medicaid link under South Dakota.
You can also call the Delta Dental Medicaid Referral Line at 1.800.627.3961.
It is possible that your provider does not know you are eligible for medical assistance. Please be sure to provide your provider with your Medical ID card each time you receive a service. If you contact your provider and they inform you that your Medical Assistance has ended, please contact your local DSS office to inquire about possible eligibility.
Contact your Benefits Specialist at your local DSS office and provide him/her with the correct information. It will then be corrected in to our system and you will be issued a new card. If you did not apply at a local office, please call 1.877.999.5612.
The pharmacy where you purchased the prescription will need to enroll with SDMA, then submit the claim to SDMA and finally reimburse you. SDMA cannot directly reimburse recipients.
SDMA will replace eyeglasses that are broken beyond repair and are returned to the provider.
Contact your Benefits Specialist at your local DSS office and provide him/her with the correct information. It will then be corrected in to our system and you will be issued a new card. If you did not apply at a local office, please call 1.877.999.5612.
The provider may not be a SDMA provider. In this case, the provider will need to enroll with SDMA as a provider so they can submit the claim for payment. Call our Department at 1.800.597.1603 so SDMA can work with the facility to get them enrolled.
In South Dakota individuals who receive a Supplement Security Income (SSI) payment are automatically eligible for Medical Assistance. If your child is no longer receiving a payment his/her eligibility would end. The Social Security Administration determines the eligibility for payments.
When this happens you will receive a notice from our Department instructing you to contact the local office nearest you to explore other possible eligibility options.
If the payment ended, but you have since received another awards letter stating you are eligible for payment, it is possible our office has not yet been notified. If you believe this is the case please call 1.877.999.5612.
Please call 1.877.999.5612 and ask for a certificate of coverage.
Requests for the lap band or other bariatric surgeries can be submitted for prior authorization consideration. Documentation must include conservative weight loss efforts, co-morbidities, psychiatric evaluation, along with a surgical evaluation.
Coverage depends on the type and reason contacts were prescribed. Please speak with your provider to learn more about coverage options.
Children ages 3 through 20 are entitled to one comprehensive well child exam each year. Sports physicals, completed through this exam, are covered.
Please contact your Benefit Specialist at your local DSS office.
Please contact your Benefits Specialist at your local DSS office or call 1.877.999.5612.
Your child will remain eligible for medical assistance provided all other eligibility factors remain the same. However, it is important that if your child needs medical services out of state, he/she will need to go to a provider who accepts South Dakota Medical Assistance.
In addition, if your child is in the Managed Care Program, he/she will need to get a referral from his/her primary care physician.
Please review the prescription drug administrative rules for specific information on what is and is not covered. Your Medical Assistance Recipient Handbook also provides this information. If you still have questions, call us
at 1.800.597.1603.
Providers will soon be able to complete their enrollment through SD MEDX. Required attachments can be uploaded, mailed or faxed to a secure, central location for scanning and entry into SD MEDX. Learn more.
Providers will be able to update contact information, address information, office hours and more via SD MEDX.
Providers will be able to submit claims, prior authorization requests, and eligibility inquiries. In turn, they will get immediate response about the status of those requests; all while doing it online.
Yes, SD MEDX is secure. It is only available to enrolled providers in the South Dakota Medical Assistance Program. Users must have a secure username and password to access SD MEDX; which comes directly from the South Dakota Medical Assistance Program. Log in credentials are sent to authorized providers via U.S. ground mail. Providers can then log in to SD MEDX.
Yes. All training opportunities are available here.
All claims on file in SD MEDX will be available to providers; this includes 6 years of converted historical claims.
No testing is required to use SD MEDX. All providers need is a computer with an Internet connection that supports Internet Explorer 6 or 7, Mozilla Firefox 3.0.8, or Safari 4.0. They will also need their secure log in credentials.
All training opportunities are available here.
The SD MEDX Response Team will be training providers on the new system. Providers will receive more details as we approach the enrollment process.
You can go to any of the statewide trainings. Providers are required to register for training sessions online. If you are unable to attend a live training session, there are online options available as well. Review the training opportunities.
South Dakota Medical Assistance requires all providers to use electronic funds transfer (EFT) as their payment method.
You will still have the same options for receiving these messages:
Additionally, providers will be able to access their RAs online.
To use SD MEDX, you will need a compatible browser and an internet connection. If you have support staff who do not have internet access and you want them to perform certain functions within SD MEDX, make sure you provide that person with the appropriate log in creditials provided by our Department.
System requirements include:
SD MEDX passwords expire every 90 days.
To search SD MEDX, please enter the desired subject matter in the search box on the top right hand side of each tab on the portal. Then click on the most appropriate link based on what you are looking for.
Please click on the Contact Us tab at the top of the page and provide either a link or description of the page where you encountering problems. Please also explain what happened so our staff are better able to correct the error.


text:
- Boots
- Creepers
- High Heels
- Platform Sandals
- Platform Shoes
- Platform Boots
- Shoes
- Sneakers
- New Rock
- Demonia
- Hades
Romany Attitude Top
was: $68.25
Black canvas quilted pattern bodice with front lace up. Imported from the UK.*Clearance items cannot be returned*
Romany Attitude Top - Clearance
- black canvas
- quilted pattern
- bodice
- front lace up
- imported
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This product carries our low price guarantee. If you find it on the internet for cheaper we will refund you the difference plus 10%!
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text:
Compare Dodge Garages and Specialists in Hastings with Who Can Fix My Car.
Enter your registration to check prices and reviews, and get your Dodge booked in today!
Compare Dodge Garages and Specialists in Hastings with Who Can Fix My Car.
Well, I had hoped that my Jeep would sail through the MOT without any problem......it didn't !!! A copper brake pipe needed replacing as well as suspension trunnions and a few other minor things. Edwin sorted it all out and at reasonable cost. At last I have found a garage and mechanic who I can trust, I have no hesitation in recommending Carma Autocare to anyone who needs work doing on their car.
Brilliant professional service from Edwin. Had my exhaust done as well as the brakes and have booked it for a service next week
Top quality workmanship at a reasonable price.... Also a very friendly and reliable service...I will be going back for any future repairs and highly recomend carma autocare..
Edwin is an excellent person, he collected my car, kept me informed of the MOT result and carried out the necessary remedial work along with the full service. He then after a long day returned my car to me. An excellent person to deal with and I highly recommend him as a mechanic and business man and will ensure all my friends and colleagues are fully aware of the service he provides.
Carma Autocare went above and beyond to get some Rear discs & pads fitted on my Cooper S, An Hour job usaully turned into over 3 hours as before my ownership the Hex bolt holding the brake disc in place was threaded very badly and was a nightmare to remove but Carma stayed on until gone 5pm to get me back on the road what a top bloke not many Garages do that these days so will be back for sure Thanks again.
I was delighted with the wonderful friendly service. I asked for new discs & pads to be fitted on all 4 wheels but, I was told that "New" front discs were not needed. How refreshingly honest of them. I could not have wished for better service. I will certainly be using "Scants" in the future for MOTs, yearly service & any repairs. The only criticism I could mention is the garage is difficult to find if you are visiting for the first time. However, I will recommend "Scants Motor Services" to my friends with complete confidence that they will receive the same excellent service that I got. A heartfelt Thank You to all at "Scants" Alan Mackereth
Fulcrum Autos
Garage On The Green located in St Leonards, is a professional full-service facility where you will save up to 50% on main dealer prices. Clutches, Cambelts, Brakes, Servicing, Exhausts, Headgaskets, MOT arrangements & preparation. We offer friendly, professional service and look forward to receiving your enquiries.
"For all your car and motoring needs in the Bexhill, Hastings and surrounding areas then look no further. At TSW Auto Repairs we provide quality, affordable servicing and repairs on all types of vehicles. We have been trading since 2000, and due to expansion at the beginning of 2007 moved to our new larger premises. Our customer base has continued to grow and grow, with most of our new customers coming through recommendation. If you're looking for car and van repairs, vehicle servicing, replacement tyres, brake repairs, exhaust systems, MOT testing, electrical diagnostics, clutch replacement, engine repairs, engine tuning or air conditioning top up and general vehicle servicing then contact us today"
Cannot fault . Very fast response , brilliant knowledge . Punctual , and am now going to make this my go to garage .
Service was really good, very competitive price, would use again,
Excellent service! Was very helpful throughout, and very very reasonable. My new go to mechanic!
Excellent service Would deffo recommend


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19 fun car road trip activities
Turn an ordinary drive into a world of fun adventures and possibilities. more
The best start a pregnant woman can give her baby is to eat a well-balanced diet, which follows the recommended amount of food from each of the five main food groups. If your diet follows this guide, vitamin and mineral supplements should not be not necessary.
Download the Kidspot guide to what vitamins and minerals you need and how to get them naturally.
Folate, or folic acid, is the exception. When you are pregnant, your folic acid needs double because your growing baby is creating thousands of new body cells, especially during the first 6 to 12 weeks of pregnancy, and your pregnant body is producing more red blood cells to support the pregnancy. If you are trying for a baby or have fallen pregnant nutritionists recommended you take a folate supplement, however always consult your doctor or midwife before taking a vitamin or mineral supplement when pregnant or breastfeeding.
High dosages of certain vitamins, such as Vitamin A, (especially during the first trimester of pregnancy) can cause birth defects. They may also pose health concerns for breastfed newborn babies. It is important you check with your doctor or midwife before taking any vitamin or mineral supplements while pregnant or breastfeeding.
This article was created for Kidspot, Australia's parenting resource for during your pregnancy.
Last revised: Monday, 23 June 2008
This article contains general information only and is not intended to replace advice from a qualified health professional.


text:
Topic: Hello
My name is Sandra Casey Buford and my husband was diagnosed with cholangiocarcinoma in April of 2002. This diagnosis was heart-breaking and scary; however I want to encourage everyone to stay the course because when I first started this journey with my husband, web-sites like this one did not exist...in fact there was limited information on the web. My family devoured the information and resources that were available and I believe that we were greatly helped through a tough time. My husband was able to live a wonderful life for five years during which our youngest daughter was married in a beautiful wedding, we traveled to Europe several times, and many more memories were created. In the end Rudy, who was 58 years old, died of an infection (septis) this past February 20th due to complications that could very well have been post-operative.... it was never confirmed because he was too sick for surgery. My words of wisdom to anyone going through this are: (1) Always, always get second and third opinions from drs. (2) Never accept a dire prognosis without exploring all options (3) Don't forego alternative treatment options and nutrition (4) Push your health insurance provider to give you what you want and need....My husband's original resection surgery at an out of state hospital was denied, but we got a medical doctor to advocate and pushed until they conceded. (5) Enjoy every single moment of life (6) surround yourself with positive people and engage in up-building experiences (7) Nurture yourself and your family spiritually


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...preferably in writing, where you can spell everything out and the reader has time to review what you said and make sure s/he understands it before making a knee-jerk reaction. I'd vote for telling everything now in hopes of forestalling problems later on (and possibly getting it fixed and not having to worry about it for a couple of months).
"When there's good news, get it out fast. When there's bad news, get it out faster." -- Chief Jack Mannion, the District


text: In 1952, Bob Sheetz purchased an Altoona, Pa., dairy store, one of five retail operations owned by his father. His second store opened its doors in 1963 and the third opened five years later. By 1969, Bob's brother Steve was serving as general manager, and the pair decided to open one store each year through


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Congress' approval of legislation to avert the so-called fiscal cliff was seen as good news to oil traders. Brent crude oil reached an 11-week high, trading at nearly $113 per barrel yesterday in London. Analysts say the U.S. averted economic calamity by approving spending cuts and preventing huge tax hikes that could have driven the world's largest economy into recession.
The fiscal cliff agreement boosted investors' appetite for riskier assets and depressed the dollar against major currencies. Economists warned that if Congress did not prevent the series of tax increases and spending cuts due to automatically start this year a recession was likely. A spike in unemployment and less consumer spending would likely depress energy demand.
Brent crude rose $1.79 per barrel on Wednesday to $112.90, before easing back to $112.70. U.S. crude rose $2.05 to a high of $93.87 per barrel, its highest price since Sept. 21, before easing back $93.12 per barrel. In afternoon trading the Dow Jones industrial average was up about 2 percent.
Analysts also noted oil markets were boosted by Chinese data pointing to a recovery in the world's second-largest economy.
National average gasoline prices are higher this week while diesel prices are near steady. The Energy Information Administration reported national average gasoline prices at $3.30 per gallon, 4 cents higher than the previous week. Average diesel prices were reported at $3.92 per gallon, down one-half of one cent per gallon from the previous week.


text:
A Different Life
View video
Career timeline for psychiatry
View video
Job Board
See the latest jobs
See Publications
Go to Expert Advice
This leaflet is for anyone who wants to know more about
antidepressants. It discusses how they work, why they are
prescribed, their effects and side-effects, and alternative
treatments. We have added some references and sources of
further information at the end of this leaflet.
If you are not clear about why an antidepressant has been
suggested for you, ask your doctor.
In most people these withdrawal effects are mild, but for a
small number of people they can be quite severe. They seem to be
most likely to happen with Paroxetine (Seroxat) and Venlafaxine
(Efexor). It is generally best to taper off the dose of an
antidepressant rather than stop it suddenly. You might like to read
our leaflet about 'Coming off
For further information, see our leaflet on Mental health in
Many women do breastfeed while on antidepressants but, again,
it's worth discussing it with your doctor. As well as the
issues listed above, you will need to think about:
A baby will get only a small amount of
antidepressant from mother's milk. Babies older than a few weeks
have very effective kidneys and livers. They are able to break down
and get rid of medicines just as adults do, so the risk to the baby
is very small.
Some antidepressants, like imipramine,
nortriptyline and sertraline only get into the breast milk in very
small amounts – it is worth talking this over with your doctor or
This leaflet was
produced by the Royal College of Psychiatrists' Public Engagement
Editorial Board.
Series Editor: Dr Philip Timms
Expert Review: Public Education Editorial Board
and Dr Lucinda Green (section on pregnancy)
Updated: February 2015. Review date:
February 2018.
This leaflet reflects the best available evidence at the time of
© Royal College of Psychiatrists. This leaflet may be
downloaded, printed out, photocopied and distributed free of charge
as long as the Royal College of Psychiatrists is properly credited
and no profit is gained from its use. Permission to reproduce it in
any other way must be obtained from email@example.com.
The College does not allow reposting of its leaflets on other
sites, but allows them to be linked to directly.
Please note that we are unable to offer advice on individual cases. Please see our
FAQ for
advice on getting help.
Please answer the following questions and press 'submit' to send your answers OR
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text:
The Bump Editors
Holiday Gift Of The Day: Crayola Light Designer
Have you seen the Best Holiday Gifts from Amazon at The Nest? It's this amazing gift guide our sister editors have put together, and we're getting tons of fantastic ideas for giving to our friends and family this season (and believe us, we need them!). Every day during the holidays, we're going to be posting our favorites, since we thought you could use the ideas too!
Today, we're into this cool toy — the Crayola Light Designer. It reminds us of a high-tech version of the Lite-Brite. (Remember those?)
Why we love it: Kids draw with light, so there's no messy marks or paint to cleanup.
Price: $40


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Freshmen Orientation
- When:
- Location:
- Campus-wide
- Description:
Welcome to the University of Baltimore!
Orientation for incoming freshmen is on June 20 and 21, and August 9 and 10, which will include student testing, registering for classes, meeting other students, and learning about UB.
If you are a freshman student, you should have received information about which orientation session you need to attend.
We can't wait to meet you!
Freshmen Orientation Schedule for students
- Contact Name:
- Kari Osborne
- Contact Email:
- email@example.com
- Contact Phone:
- 410.837.4397
If you need accommodations to participate in this event, please contact the person listed above at least 10 days prior to the event.


text:
Pharmacogenomic Evaluation of Antihypertensive Responses 2 (PEAR2)
This study has been completed.
University of Florida
National Institute of General Medical Sciences (NIGMS)
Information provided by (Responsible Party):
University of Florida
ClinicalTrials.gov Identifier:
First received: September 15, 2010
Last updated: March 24, 2017
Last verified: March 2017
- Full Text View
- Tabular View
- Study Results
- Disclaimer
- How to Read a Study Record
Detailed Description:
There are many medications available for the treatment of high blood pressure (hypertension), but finding the right one for a specific patient can be challenging. In fact, it is estimated that less than 50% of people with hypertension have their blood pressure under control. The hypothesis is that genetic differences between individuals influence their response to antihypertensive medications. This study is aimed at determining the genetic factors that may influence a person's response to either a beta-blocker or a thiazide diuretic. The hope is that through this research, the investigators may someday be able to use an individual's genetic information to guide the selection of their blood pressure medicine, leading to better control of blood pressure, and less need for the current trial and error process.
|Drug: Metoprolol Drug: Chlorthalidone
|Phase 4
|Study Type:
|Study Design:
|Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
|Official Title:
|Pharmacogenomic Evaluation of Antihypertensive Responses 2
Resource links provided by NLM:
MedlinePlus related topics: Blood Pressure Medicines
Drug Information available for: Chlorthalidone Metoprolol Metoprolol tartrate Metoprolol fumarate Metoprolol succinateU.S. FDA Resources
Further study details as provided by University of Florida:
Primary Outcome Measures:
- Change in Blood Pressure From Baseline to Treatment [ Time Frame: after 6-8 weeks of treatment ]Response to blood pressure medication will be assessed by measuring blood pressure before and after treatment
Secondary Outcome Measures:
- Adverse Metabolic Effects [ Time Frame: after 6-8 weeks treatment ]Change in glucose after treatment with study medication
|Study Start Date:
|August 2010
|Study Completion Date:
|April 2014
|Primary Completion Date:
|April 2014 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: Metoprolol + Chlorthalidone
Study participants in this group had their current hypertension treatment withdrawn, baseline labs drawn and hypertension documented. Participants were initiated on metoprolol tartrate 50 mg twice daily for two weeks, followed by dose titration to 100 mg twice daily for six additional weeks if blood pressure (BP) > 120/70 mmHg. BP measures were again recorded. Participants entered a washout where metoprolol was titrated, then discontinued, and the patient's hypertension was re-established. After another set of identical baseline labs, study participants were initiated on chlorthalidone 25 mg four days per week (Monday, Wednesday, Thursday, Saturday) 15 mg daily for two weeks, followed by 25 mg daily for an additional six weeks.
Drug: Metoprolol
Metoprolol 50 mg twice daily titrated to 100 mg twice daily
Note: due to discontinuation of the manufacture of chlorthalidone 15 mg, effective Jan 1, 2013; the starting dose of chlorthalidone will be 25 mg 4 times per week (Mon, Wed, Thur, Sat) with subsequent titration to 25 mg daily.
Other Names:Drug: Chlorthalidone
Chlorthalidone 25 mg 4 times per week titrated to 25 mg daily
Other Name: Thalitone
Detailed Description:
The proposed work should help move toward the long-term goal of selection of antihypertensive drug therapy based on a patient's genetic make-up. Hypertension (HTN) is the most common chronic disease for which drugs are prescribed, and the most prevalent risk factor for heart attack, stroke, renal failure and heart failure. Responses to antihypertensive drug therapy exhibit considerable interpatient variability, contributing to poor rates of HTN control (currently about 40-50% in the US), and frequent nonadherence and dropout from therapy. We propose to identify genetic predictors of the antihypertensive and adverse metabolic responses to two preferred and pharmacodynamically contrasting drugs, a beta-blocker (metoprolol) and a thiazide diuretic (chlorthalidone) in a sequential monotherapy design in 400 hypertensive individuals. Data collected will include home and clinic blood pressure, blood samples for testing for adverse metabolic effects and other biomarkers, RNA, and DNA and urine sample. We will conduct genome-wide association single nucleotide polymorphism (SNP) genotyping and data from the study will be used for replication of findings from the previous PEAR trial, along with new discoveries. The primary aims are to define the genetic determinants of the antihypertensive response and adverse metabolic responses (e.g. changes in glucose, triglycerides and uric acid). The proposed research is significant because genetically-targeted antihypertensive therapy could lead to dramatically higher response rates and fewer adverse effects than the usual trial-and-error approach. This would likely lead to higher rates of HTN control, less need for polypharmacy, reduced health care costs, and improved outcomes.
|Ages Eligible for Study:
|18 Years to 65 Years (Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- An average seated home diastolic blood pressure (DBP) > 85 mmHg and < 110 mmHg and home systolic blood pressure (SBP) < 180 mmHg.
- Subjects must also have an average seated (> 5 minutes) clinic DBP between 90 mmHg and 110 mmHg and SBP < 180 mmHg
Exclusion Criteria:
- Secondary forms of hypertension (HTN) (including sleep apnea)
- Isolated systolic HTN
- Other diseases requiring treatment with BP lowering medications
- Heart rate < 55 beats/min (for metoprolol only)
- Known cardiovascular disease (including history of angina pectoris, heart failure, presence of a cardiac pacemaker, history of myocardial infarction or revascularization procedure, or cerebrovascular disease, including stroke and TIA)
- Diabetes mellitus (Type 1 or 2)
- Renal insufficiency (serum creatinine > 1.5 in men or 1.4 in women)
- Primary renal disease
- Pregnancy or lactation
- Liver enzymes > 2.5 upper limits of normal
- Current treatment with NSAIDS, cyclooxygenase-2 (COX2) inhibitors, oral contraceptives or estrogen.
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01203852
Please refer to this study by its ClinicalTrials.gov identifier: NCT01203852
|United States, Florida
|University of Florida
|Gainesville, Florida, United States, 32610
|United States, Georgia
|Emory University School of Medicine
|Atlanta, Georgia, United States, 30322
|United States, Minnesota
|Mayo Clinic, Division of Hypertension
|Rochester, Minnesota, United States, 55905
Sponsors and Collaborators
University of Florida
National Institute of General Medical Sciences (NIGMS)
|Principal Investigator:
|Julie A Johnson, PharmD
|University of Florida
More Information
Additional Information:
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Keywords provided by University of Florida:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on September 21, 2017
Additional Information:
Hamadeh IS, Langaee TY, Dwivedi R, Garcia S, Burkley BM, Skaar TC, Chapman AB, Gums JG, Turner ST, Gong Y, Cooper-DeHoff RM, Johnson JA. Impact of CYP2D6 polymorphisms on clinical efficacy and tolerability of metoprolol tartrate. Clin Pharmacol Ther. 2014 Aug;96(2):175-81. doi: 10.1038/clpt.2014.62. Epub 2014 Mar 17.
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Shahin MH, Sá AC, Webb A, Gong Y, Langaee T, McDonough CW, Riva A, Beitleshees AL, Chapman AB, Gums JG, Turner ST, Boerwinkle E, Scherer SE, Sadee W, Cooper-DeHoff RM, Johnson JA. Genome-Wide Prioritization and Transcriptomics Reveal Novel Signatures Associated With Thiazide Diuretics Blood Pressure Response. Circ Cardiovasc Genet. 2017 Jan;10(1). pii: e001404. doi: 10.1161/CIRCGENETICS.116.001404.
|Responsible Party:
|University of Florida
|ClinicalTrials.gov Identifier:
|NCT01203852 History of Changes
|Other Study ID Numbers:
U01GM074492-06 ( U.S. NIH Grant/Contract )
|Study First Received:
|September 15, 2010
|Results First Received:
|April 29, 2015
|Last Updated:
|March 24, 2017
|Studies a U.S. FDA-regulated Drug Product:
|Studies a U.S. FDA-regulated Device Product:
Keywords provided by University of Florida:
antihypertensive drug
blood pressure
Additional relevant MeSH terms:
Vascular Diseases
Cardiovascular Diseases
Antihypertensive Agents
Anti-Arrhythmia Agents
Autonomic Agents
Peripheral Nervous System Agents
Physiological Effects of Drugs
Adrenergic beta-1 Receptor Antagonists
Adrenergic beta-Antagonists
Adrenergic Antagonists
Adrenergic Agents
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action
Natriuretic Agents
Sodium Chloride Symporter Inhibitors
Membrane Transport Modulators
ClinicalTrials.gov processed this record on September 21, 2017


text:
Transplant doc, Nobel winner Murray dies in Boston
A doctor who performed the world's first successful kidney transplant and won a Nobel Prize for his pioneering work has died in Boston. Dr. Joseph E. Murray was 93.
Brigham and Women's Hospital spokesman Tom Langford says Murray had a stroke on Thanksgiving and died there Monday.
In the early 1950s, there had never been a successful human organ transplant. Murray and his associates at what was then Boston's Peter Bent Brigham Hospital developed new surgical techniques after gaining knowledge by transplanting kidneys on dogs. In December 1954, they found the right human patients: a 23-year-old man with end-stage kidney failure and his identical twin.
After the operation, the sick twin had a functioning kidney transplanted from his brother. He lived another eight years, marrying a nurse he met at the hospital and having two children.
(Copyright 2012 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.)


text:
Silver Cloud Estates, LLC
1550 Caton Center Drive
Suite H
Halethorpe, MD 21227
Phone 410-565-6600
Fax 410-565-6601
Pure Spearmint Extract
Pure Spearmint Extract
Pure Spearmint Extract has a wonderful, sweet, minty flavor and aroma. It is what to use when a recipe calls for "mint" extract. Sweeter than peppermint, it does not impart the cooling sensation characteristic of peppermint.Pure Spearmint Extract can be used in a wide range of baking applications. One teaspoon is sufficient for your typical cake or cookie recipe.
Silver Cloud's Pure Spearmint Extract contains ethyl alcohol, water and spearmint oil. This extract is sugar and gluten-free.
What is an Additional Shipping Charge?
Many extracts and flavors contain ethyl alcohol or other ingredients which make them hazardous when shipping. When a product is hazardous, the shipper (UPS, Federal Express) charges a hazardous shipping fee of to cover the added cost associated with transporting hazardous goods. This fee is typically $25.00. This fee is in addition to the standard shipping charges.
There are exemptions for "limited quantities." These exemptions are based on the hazardous group in which the extract or flavor is categorized. Depending on the group associated with the product the exemption is typically for a packaging unit of a gallon or less. If you are charged an additional shipping charge for a gallon, you should try entering the order as 4 quarts. We are adding a 4 quart option to the items requiring an additional shipping charge. In most cases purchasing 4 quarts without the additional shipping charge is less than the cost of a gallon with the added $25.00 fee. The hazardous shipping charge is for the package, not the unit. If you purchase 4 gallons in lieu of 1 gallon you are still charged $25.00 since our boxes hold 4 gallons. Orders of 8 gallons are charged $50.00 or $25.00 for each 4 gallon box.Please note, Silver Cloud Estates, LLC offers wholesale prices to businesses with a Federal Tax ID Number. If you would like to open a wholesale account please contact us.
If you have questions regarding the most economical way to ship product, please do not hesitate to call us at 410-565-6600.
Featured Stores


text:
Letters ThreeRiddles are little poems or phrases that pose a question that needs answering. Riddles frequently rhyme, but this is not a requirement.
I know a word
Of letters three,
Add one more letter
And none there will be.
What is the word?
AnswerThe word is one.
Adding another letter, N, gives the word 'none'.
What Next?
See another brain teaser just like this one...
Or, just get a random brain teaser
If you become a registered user you can vote on this riddle, keep track of
which ones you have seen, and even make your own.
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text:
Judging by figures released at a Paris press briefing on January 20, the waning resurgence of the commercial turboprop market has, if anything, resumed at a stronger pace than at any time since the segment began reclaiming lost ground from the regional jet market a half-decade ago, at least for Franco-Italian manufacturer ATR. In fact, the EADS-Alenia joint venture appeared to take a commanding lead over its only Western rival in the segment in both sales and back order totals last year.
ATR finished the calendar year with an order total of 80 airplanes and a backlog of 159. Meanwhile, Canada's Bombardier announced orders for just 45 Q400s.
Because Bombardier's fiscal year ends on January 31, it released its last official Q400 status report after the last day of its third fiscal quarter, on October 31, at which time its backlog stood at just 67. Extrapolating its October 31 calendar-year-to-date delivery total of 42 to roughly four airplanes per month and considering a 15-aircraft order from India's SpiceJet in December, Bombardier would have finished the calendar year with a backlog of about 74 airplanes.
Although one wouldn't consider Bombardier's performance substandard by recent years' criteria, it only seems less than impressive compared with ATR's out-of-the-ordinary showing. ATR collected orders for exactly twice as many turboprops in 2010 as it logged in 2009, while its backlog now accounts for some three years of production at its current rate of just over 50 airplanes a year.
Carrying its largest backlog since early 2009 and emboldened by projected demand for some 3,000 turboprops over the next 20 years, ATR has decided to raise its annual production rate to 70 airplanes by next year, at which point it expects revenues to rise from some $1.35 billion to $1.8 billion. ATR's backlog includes 107 of the new ATR 72-600, scheduled for first delivery by the middle of this year, and five ATR 42-600s, the first of which the company plans to ship by year-end. It also holds unfilled orders for 42 of the current-generation ATR 72-500s and four ATR 42-500s.
"I am delighted that ATR has regained speed in 2010 by doubling the previous year's order intake," said ATR CEO Filippo Bagnato. "We registered significant orders from new customers in Latin America and the Caribbean region, as well as strong signs of confidence of lessor Air Lease Corporation, thus increasing our worldwide presence. We now have a strong baseline to prepare ATR for the next important step."
Still, ATR's presence in North America remains weak, a condition it hopes to remedy with the help of the 600 Series, with its new Thales avionics suite, more powerful Pratt & Whitney Canada PW127M turboprops and an option for a forward passenger door that will allow the jetway access particularly valued by U.S. customers.


text:
The San Jose Independent Police Auditor's Office is seeking teens to serve on the office's Teen Leadership Council.
Teenagers with an interest in leadership, community outreach, youth and police encounters and local government, from every ethnic, socioeconomic and educational background, are encouraged to apply.
Applicants must be 15 to 18 years old and live or attend school in San Jose.
The Teen Leadership Council was created in 2011 by LaDoris Cordell, San Jose's independent police auditor.
Members of the teen council meet monthly and participate in workshops, meet local leaders and develop their leadership skills. Meetings are usually on the third Friday of each month from 5 to 7 p.m. in downtown San Jose.
Applications must be filed by May 2 at 11 p.m.
For more information and applications, visit sanjoseca.gov/ipa or call Diane at 408.794.6226.


text:
Gus comes to Harley's rescue.
Daisy faces a huge challenge.
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|Days of our Lives: Jen Lilley and Meredith Scott Lynn team up to rap
Jen Lilley (Theresa) and Meredith Scott Lynn (Ann) of Days of our Lives, also known as the dynamic-duo on the show, came up with the ultimate unique Holiday gift for their cast members. A video rap depicting the show and the every day goings on in the town of Salem.
How clever! Guaranteed you will watch this over and over and burst at the seams with laughter each time, as you see the antics of your favorite Salemites. Even if you don't watch the show you will enjoy this and be amazed at what you are missing in your life for an hour each day.
Soap Tweets
Follow Your Faves


text:
15 U.S. Code § 1666i–2 - Additional limits on interest rate increases
prev | next
(a) Limitation on increases within first year
Except in the case of an increase described in paragraph (1), (2), (3), or (4) of section 1666i–1 (b) of this title, no increase in any annual percentage rate, fee, or finance charge on any credit card account under an open end consumer credit plan shall be effective before the end of the 1-year period beginning on the date on which the account is opened.
(b) Promotional rate minimum term
No increase in any annual percentage rate applicable to a credit card account under an open end consumer credit plan that is a promotional rate (as that term is defined by the Bureau) shall be effective before the end of the 6-month period beginning on the date on which the promotional rate takes effect, subject to such reasonable exceptions as the Bureau may establish, by rule.
Source(Pub. L. 90–321, title I, § 172, as added Pub. L. 111–24, title I, § 101(d),May 22, 2009, 123 Stat. 1738; amended Pub. L. 111–203, title X, § 1100A(2),July 21, 2010, 124 Stat. 2107.)
2010—Subsec. (b). Pub. L. 111–203substituted "Bureau" for "Board" in two places.
Effective Date of 2010 Amendment
Amendment by Pub. L. 111–203effective on the designated transfer date, see section 1100H ofPub. L. 111–203, set out as a note under section 552a of Title 5, Government Organization and Employees.
Effective Date
Section effective 9 months after May 22, 2009, except as otherwise specifically provided, see section 3 ofPub. L. 111–24, set out as an Effective Date of 2009 Amendment note under section 1602 of this title.
LII has no control over and does not endorse any external Internet site that contains links to or references LII.


text:
Hercules Wimbledon AC's senior men produced their best team performance since lifting the title in 1970 when they finished 12th in Saturday's South of England Cross-Country Championships.
The solid team effort was achieved despite the absence of three of the Surrey title-winning team, Ben Toomer, Liam White and Matt Sharp.
Fred Slemeck led the team home over 15km on Parliament Hill finishing 41st of almost 1,000 runners in 55 minutes 11 seconds, with Kieran White 84th in 57:40, Joe Clark 105th in 58:22, Jonathan Cornish 119th in 58:50, Rob Tuer 155th in 59:58 and Phil Glynn completing the scoring six finishing 192nd in 61:09.
Matthew Gibbons finished 43rd out of 258 runners in the boys U15 4.5km race in 17:25, while Oscar White was 45th out of 284 runners in the boys U13 3km race in 12:48.
Best of the Hercules Wimbledon women in action at Parliament Hill Fields was Zoe Illis who was 82nd out of 151 runners in the U17 5km race in 24:21.
This weekend, Hercules Wimbledon host the annual East Surrey League cross-country relays on Wimbledon Common.
They start near the corner of North View and West Place at 2pm.
The U13s run two miles, the other younger age groups run in teams of three while the seniors comprise teams of four with each runner covering two miles.
Hercules Wimbledon's track and field training sessions take place at Wimbledon Park athletics stadium on Tuesday and Thursday evenings starting at 6.30pm and Sunday mornings at 10.30am. Further details from coaching coordinator Maurice Sharp on 020 8337 8707.


text:
The Spirit of Maine
Portland Headlight, Cape Elizabeth, Maine
Let your Maine adventures begin! Get on Route Route 109 (Exit 2 off the new and improved Maine Turnpike) in Wells and head north/west to the city of Sanford. From there, take Route 11 through the picturesque, history-laden towns of Limerick and Limington. (Note: You can take Route 25 over to Standish and check out the Daniel Marrett House, a marvelous 1789 Georgian mansion which once held money from Portland banks for safekeeping during the War of 1812.) Continue along the western shores of Sebago Lake to the town of Naples, stopping off along the way to browse through the many quaint antique shops that line the winding road. Nearby, Sebago Lake State Park is great place for a picnic and some afternoon fun in the sun.
From Naples, take Route 302 through the delightful town of Bridgton Pick up Route 117 and head north along the meandering shores of Long Lake to Route 35.
Take Route 35 north to the classic New England village of Bethel. A 19th century haven for the city weary, Bethel still beams with the sights and sounds of a simpler time. A number of the elegant grand resorts and inns remain, as does the warm local hospitality. Sunday River Ski Resort just outside of town offers wonderful summer recreation opportunities. Hiking, biking and golf are just a few of the activities you can enjoy amidst the spectacular mountain vistas of nearby Grafton Notch State Park and White Mountain National Forest.
Pick up Route 2 north/east in the town of Newry and head through the town of Rumford and cross the river into Mexico. Pick up Route 17 in Mexico, and head north along one of Maine's most scenic highways. Wonderful views of the Swift River and spectacular mountain views greet you around each bend. Along the way, check out the Coos Canyon State Park. Legend has it this was the first place in America where gold was discovered. Before you know it, you'll arrive in the Rangeley Lakes region, one of Maine's most spectacular four-season destinations.
Seven lakes - Aziscohos, Richardson, Cupsuptic, Mooselookmeguntic, Kennebago, Umbagog and Rangeley - and dozens of ponds dot the region's mountainous landscape. While you can do just about anything here, the region's featured summer activities include: hiking, canoeing and fishing.
Take Route 16 north to Stratton, a mountain town offering sweeping view of Flagstaff Lake. Here, you can also hike the Bigelow Mountain Range Trail all the way to breathtaking Cranberry Peak.
Take Route 27/16 in Stratton and turn south towards the Carrabassett Valley. Here you'll find Sugarloaf/USA, one of the most popular ski destinations in the East. But Sugarloaf offers more than just winter fun. During the summer months, hiking and biking opportunities abound and Sugarloaf's 18-hole championship course is consistently rated among the most scenic in North America. (But be warned - even the most proficient golfers should bring along an extra sleeve of golf balls!!)
Continue south on 27/16 to the quaint, friendly mountainside village of Kingfield, where you can check out the antique treasures in the old-fashioned hotel located in the center and visit the Stanley Museum honoring the Kingfield-born Stanley family (inventors of the Stanley Steamer steam car).
Continue South on route 27/16 through North Anson and on to Bingham. Head back north a few miles along 201A/27/16 and pick up Route 201 in the town of Solon - one of four National Scenic Byways in the state. Affectionately known as "moose alley" for the frequent moose sightings it offers, this stretch of highway leads you north into the awesome landscape of the upper Kennebec River Valley and into the heart of Maine's whitewater rafting country. As you near The Forks, outdoor adventure centers abound and the folks here will help you experience the outdoor adventure of a lifetime.
For history buffs and outdoor enthusiasts alike, the Kennebec-Chaudiere International Heritage Corridor offers excitement and adventure at every turn. The trail links the histories of Maine and Quebec along two glorious rivers, Maine's Kennebec and Quebec's Chaudiere, and two scenic highways, Maine's Route 201 and Quebec's Route 173. Explore the great outdoors and discover the region's intriguing past.
Continue along Route 201 to the town of Jackman, a border town known to Mainers as the gateway to Canada. Though you'll not find any fancy nightclubs here, the people are friendly and the fishing, hunting and boating are simply incredible. For amazing views of Attean Lake and its adjoining lakes and ponds, stop at the rest area between The Forks and Jackman.
Just south of Jackman, you can pick up Route 6/15 and head east towards Moosehead Lake and the picturesque town of Greenville. The area's tourism history dates all the way back to the 1890s. With such an amazing variety of things to see and do, including spectacular Mt. Kineo, a magnificent rock edifice rising to the sky out of the middle of Moosehead Lake, it's not hard to see why. Swimming, boating and fishing opportunities abound in the 40 mile-long lake. You can also go on safari! - a Moose Safari that is. And the gracefully restored S/S Katahdin steamship offers scenic cruises around the lake.
Take Route 6/15 to Guilford. Pick up Route 16 again and head east through the towns of Dover-Foxcroft and Milo. Once you're in Milo, keep an eye out for Route 11. Head north on 11 to the town of Millinocket, from where you can visit extraordinary Baxter State Park and mile-high Mt. Katahdin, Maine's tallest peak. (Due to the park's limited admission policy, you should contact the Park Reservation Clerk in Millinocket prior to visiting the park). In Ashland, you can visit the fascinating Ashland Logging Museum and catch a glimpse of the region's logging past. Exhibits include a blacksmith shop, machine sled and logging equipment. After you've had a taste of Maine's great logging tradition, take Route 163 over to Presque Isle.
From Presque Isle, you can experience Maine's centuries old Acadian heritage. In fact, a visit to the Acadian Village in Van Buren makes for an eye-opening side trip. Its 18th century attractions include a school, old homesteads complete with period furnishings, a barber shop, log church and even an old train station. Named an "All-American City" in 1966, Presque Isle is the commercial center of Aroostook County – the largest county in America east of the Mississippi River – and the gateway to Maine's glorious North Woods.
Now that you've experienced the natural splendor of Maine's incredible interior, it's time now to chart your course to the sea.
Head south on Route 1 through Aroostook County down through Houlton and on to Calais, stopping along the way at the Moosehorn National Wildlife Refuge. Catch Route 190 south/east in Perry and head to Eastport, where you can experience a wonderful whale-watching cruise, discover the area's unique history and close ties to the War of 1812 or catch a glimpse of Old Sow - the western hemisphere's largest whirlpool located on nearby Deer Island.
Eastport is also close by to Franklin Delano Roosevelt's famed summer residence at Campobello Island (makes for a great side trip!). Eastport's quaint downtown also offers a variety of shops, restaurants and galleries.
Head back to Route 1 and continue south along the coast past beautiful Cobscook Bay. Take 189 east out to Lubec and check out picturesque West Quoddy Light, the easternmost point in the United States. Head back towards West Lubec.
Take Route 191 south/west through the picturesque town of Cutler and on to historic Machias, where in 1775, a group of Machias rebels stormed and seized the British gunship Margaretta leading to what many believe was the first American victory of the Revolutionary War. While in town, you can also visit historic Burnham Tavern, where this early act of revolution was planned.
After your historical interlude, continue south on Route 1 to Jonesboro. Take Route 187 and begin the winding journey southward along Maine's famed coastline. Charming Jonesport is the quintessential Maine lobstering community. Together with adjoining Beals Island, they make up Maine's largest lobstering fleet. Enjoy the towns' antique shops, galleries, bookstores and restaurants and B&Bs.
Take 187 north back to Route 1 South. Take Route 3 south in Ellsworth and head towards Mount Desert Island. New England's second largest island, Mount Desert, the home of Acadia National Park, has inspired artists for generations - and offers an abundance of unique recreation opportunities for outdoor enthusiasts.
Jump on 102 South down to Bass Harbor and check out the Bass Harbor Lighthouse, situated on a dramatic precipice 56 feet above sea level. Continue to beautiful Southwest Harbor, a seaside village featuring shops, cafes and charming inns and B&Bs.
Head to Somesville along Somes Sound, the only fjord on the U.S. Atlantic coast, then east/south on 198 and 3 to the popular yachting destination of Northeast Harbor. Here, the fabulous Asticou Terraces and Asticou Azalea Gardens provide acres of beautiful gardens to explore, and nearby inns offer exquisite accommodations. From here, Route 3 takes you to the legendary vacation destination of Bar Harbor and Acadia National Park. Opportunities for fabulous shopping, sightseeing and dining abound in Bar Harbor; in addition, the town offers a wonderful range of accommodations to suit any taste, from rustic to refined.
While in town, visit the Abbe Museum now boasting two locations on Mt. Desert island. Opened in the Fall of 2001, the new museum located in downtown Bar Harbor. The original Abbe Museum is located at Sieur de Monts Spring in Acadia National Park. Both locations celebrate Maine's Native American life and culture from the past to the present. The museum's collection includes more than 50,000 objects spanning 10,000 years.
If you're interested in Bar Harbor's roots as a summer resort for American tycoons, the town's guided Victorian Walking Tour reveals how the rich and famous lived and played at the turn of the century.
You can also bike the lovely network of carriage paths (designed and built by John D. Rockefeller Jr.) in Acadia National Park, as well as hike the park's scenic trails and enjoy an island tradition of tea and popovers at the Jordan Pond House. Locals will advise you to watch a sunrise from the summit of Cadillac Mountain, which is easily accessible by car. If you'd like to do some exploring on the water, Bar Harbor offers opportunities for kayaking, windjammer day-sails and whale- and puffin-watching cruises.
From Bar Harbor, take Route 3 over the Mt. Desert Island Bridge back to Ellsworth. While in Ellsworth, you can tour the spectacular Georgian-style Colonel Black Mansion (built in 1862). Also, the Stanwood Homestead Sanctuary is a must-see.
Continue south on Route 1 through the town of Bucksport, and into the heart of Maine's spectacular Mid Coast region. A delectable blend of Maine's time-honored maritime traditions and upscale sophistication, the Mid Coast region is indeed a unique treasure. Here you'll find bait and tackle shops sharing village blocks with dazzling art galleries.
In Camden, you can stroll through the picturesque streets of the historic downtown to enjoy shops, harbor side restaurants, and pubs. Enjoy the sweeping harbor views from Harbor Park.
Then it's on to Rockland, the home of Maine's world-famous windjammer fleet. A windjammer cruise is a spectacular way to experience the wonders of Maine's coast. You can also visit the nationally acclaimed Farnsworth Art Museum and experience Maine's beauty through the eyes of famous Maine landscape artists.
The Farnsworth Museum also features the Wyeth Center, which houses thousands of works by N.C., Andrew and Jamie Wyeth - the first family of Maine painting. The Olson House in nearby Cushing was the setting for many of Andrew Wyeth's paintings, including the poignant Christina's World.
Pick up Route 32 south in Waldoboro and loop down along the shores of Muscongus Bay to the quaint fishing village of New Harbor. Hook up with Route 130 south and visit the absolutely stunning lighthouse at Pemaquid Point. Head back north on Route 130 towards Damariscotta and Newcastle, two quintessential New England villages. The main street linking these two towns is lined with magnificent 19th century storefronts.
While in town, check out the Round Top Center for the Arts, a 1924 farm that now offers a full schedule of cultural events, including concerts, classes, exhibitions and festivals.
Continue south on Route 1 to the town of Wiscasset. Situated on a hillside sloping gently towards the Sheepscot River, Wiscasset's streets are lined with antique shops, historic homes, galleries and restaurants. Formerly an 1852 sea captain's mansion, The Musical Wonder House features an astounding collection of music boxes, reed organs, Victrolas and other melodious wonders.
After you've experienced the wonders of Wiscasset, continue on Route 1 south to Bath. Not to be missed is the Maine Maritime Museum – located on the grounds of the 19th century Percy and Small Shipyard. While in town, you can also browse the historic downtown, bustling with shops, pubs and restaurants.
Interested in history? Then take Route 209 south to Popham Beach. Here you'll find historic Fort Popham, a forbidding, massive stone structure that protected Bath's shipbuilding interests during the Civil War. Nearby Popham Beach State Park features one of Maine's most famous and most beautiful sandy beaches. A great place to soak up some summer rays!
Head back north on Route 209 and pick up Route 1 south towards the city of Brunswick. Maine's oldest college town, Brunswick is home to Bowdoin College, formed in 1794. The picturesque Bowdoin campus is matched only by the old New England charm of the town's Main Street.
Continue south on Route 1 to Freeport, home to legendary retailer LL Bean as well as a whole host of other brand name outlets and retail stores.
Nearby Yarmouth is a peaceful, charming Maine town featuring 18th and 19th century homes and buildings, historic green spaces, quaint stores and antique shops. If you're lucky enough to be here in mid-July, you can take in the family fun at the perennially popular Yarmouth Clam Festival (July 19 -21).
After you've had your fill of "steamers", jump on 95 South for a quick ride down to Portland. As one of the Northeast's most sophisticated small cities, Portland pulses with a delightfully vibrant urban atmosphere, yet retains all the warmth and charm of a close-knit community.
Portland's art scene is simply electrifying, as evidenced by it's many galleries, theaters, dance companies, performance halls and museums. Portland also boasts dining options as delicious as its arts scene. In fact, per capita, Portland is said to be home to more places to dine than any other American city, save San Francisco; the caliber of the fare to be found here has been noted in Bon Appetit, Travel & Leisure and Wine Spectator.
The Portland Museum of Art, located on historic Congress Street, is a landmark I.M. Pei-designed building that holds one of the most celebrated art collections in the Northeast. The museum also hosts exciting exhibitions and programs that showcase the work of artists including Mary Cassatt, Andrew Wyeth, Edgar Degas, Pablo Picasso and Pierrre-Auguste Renoir. Of special note is a body of 19 significant works by Winslow Homer.
The Portland Performing Arts Center's elegant theater seats just 290 people, but has earned a reputation for the wonderful performances it hosts. It is also home to the Ram Island Dance Company, a notable modern dance troupe.
The Center for Cultural Exchange hosts diverse and lively musical performances and events, featuring artists from all over the world. And the beautifully appointed 1913 Merrill Auditorium with its vaulted ceilings and balconies and 5,000 pipe Kotzchmar Organ has also taken center stage in the recent past. It has hosted entertainers as diverse as Natalie Merchant, Taj Mahal, Itzhak Perlman and BB King, and a Boston Globe opera critic deemed it "drop-dead gorgeous." The auditorium is well worth a visit - preferably when the resident Portland Symphony Orchestra is giving one of its celebrated performances.
Portland is also a wonderful city to explore on foot. Greater Portland Landmarks offers walking tour maps of the city's four main historic districts. Enjoy the refreshingly pleasant sea breezes as you stroll along the city's tree-lined sidewalks beneath the warm, bright blue summer skies.
On the Portland "must-do" list is shopping and dining in the brick-and-cobblestone Old Port District, taking a scenic ferry ride to one of the Casco Bay Islands, visiting the highly regarded Portland Museum of Art and the adjacent Children's Museum of Maine, and touring the incredibly ornate, Italianate Victoria Mansion.
There are also wonders to explore just outside of town. Visit South Portland, where the Spring Point Ledge Light rests on a breakwater adjacent to the Portland Harbor Museum - which features as its centerpiece the bow of America's last clipper ship, the Snow Squall. This 157-foot beauty was left to rot in South America in 1864, but portions of the vessel were recently recovered and are being restored at the museum.
Just to the south is Fort Williams Park. Here, you'll find heart-stopping views of the sea and access to world-famous Portland Head Light. Commissioned by George Washington in 1791, this light enjoys a long and fascinating history, and has spawned its fair share of legends. A local favorite dates to the early 1900s, when the lighthouse-keeper's parrot (who reportedly cursed like a pirate) acted as a barometer, telling the keeper to turn the light on when a storm was approaching. Henry Wadsworth Longfellow also visited the light frequently, and is said to have penned some of his poetry here. Learn more about this landmark beacon at the museum housed in the former lighthouse-keeper's quarters.
A few miles south on Route 77 are two beautiful sandy beaches at Crescent Beach State Park and Scarborough Beach State Park. Stop to soak up some sun and frolic in the gentle surf. Continue on 77 to 207, where you can take a side trip to Prouts Neck, home of revered painter, Winslow Homer. An unmarked trail beginning at Winslow Homer Road (ask for directions at the nearby inn) winds along the cliffs where the artist was often inspired.
Take 207 out to Route 1 and head south to Old Orchard Beach, where the seven-mile sandy beach is a haven for sunbathers and sand-sculptors (a sandcastle competition draws aficionados from near and far each August). In addition, Old Orchard's historic pier and amusement park offer hours of fun for families.
Continue on Route 1 South to Kennebunkport, a charming coastal village that was plunged headlong into worldwide fame when summer resident, George H. Bush, became President back in 1989. You can take a scenic drive along coastal Route 9 to catch a glimpse of the Bush mansion on beautiful Walker Point, as well as the other magnificent summer homes that grace the picturesque shoreline.
Enjoy a stay at one of Kennebunkport's magnificent inns, one of which houses an acclaimed four-star restaurant. Many inns and B&Bs are located just steps away from the exciting dining and shopping area at Dock Square in the town's center.
In Kennebunk (located due west on route 9A), you can tour the stunning Brick Store Museum, a wonderful three-building complex that houses local memorabilia, fine art, antique furniture and nautical exhibits. And, right up the street is the historical White Columns home (built in 1853), which offers a wonderful tribute to the Victorian era.
Head south on Route 1 to Wells, where you'll find wide, sandy beaches, antique shops and the Rachel Carson Wildlife Refuge, which provides habitat for over 250 species of birds.
Head south on Route 1 to Ogunquit. This seaside resort's heralded natural beauty drew artists from near and far in the late 1800s, making it one of the nation's first art colonies. Among the many artists who found inspiration here were Maurice Prendergast, Walt Kuhn and Edward Hopper. Their legacy lives on today in the exquisite galleries and museums that line the village's quaint streets and scenic coves.
Of special note is the Ogunquit Museum of American Art, dedicated exclusively to 20th-century American art. In addition to housing over 1,300 significant paintings, sculptures, drawings and prints, the museum's location overlooking the Atlantic is truly breathtaking - inspiring a former Director of the Metropolitan Museum of Art to deem it "the most beautiful small museum in the world."
While in town, take a walk on Marginal Way, a footpath offering amazing views of the sea as well as of the summer "cottages" that line the shore. The path ends at Perkins Cove, a picturesque harbor surrounded by galleries, restaurants and boutiques, and which features a draw footbridge across its entrance.
You can also kick back and relax on the warm, white sands of three-mile long Ogunquit Beach, recently rated one of the ten best beaches in the U.S. Take in a show at the historic Ogunquit Playhouse, a grand old summer-stock theater first opened in 1933. The Ogunquit area also offers a number of exquisite inns, many within walking distance of the beaches and attractions around town.
The next stop along your tour of Maine's fabled South coast is The Yorks. Explore the village of York Beach, where Victorian-era shops line the boardwalk at Long Sands Beach. Soak up some sun, visit the local amusement park and zoo, and stop at the village's restaurant & taffy shop, which has been owned by the same family since 1896. In addition, make sure to visit the circa-1879 Cape Neddick (Nubble) Light; the beacon's grounds make for a very scenic picnic spot.
Another interesting stop is Old York Village, where a number of these buildings are open for tours. Among these is the Old Gaol, a prison dating from 1719 and believed to be the oldest remaining public building of the English colonies. If you are interested in gravestone rubbing, don't miss the Old Burying Ground, where stones bear the Old English spellings of 18th-century town members. Also of interest is York Village's Civil War Monument; upon inspection, you'll notice that the soldier is wearing a Confederate uniform. Due to a shipping mistake, York's statue is on display somewhere south of the Mason-Dixon line.
Head south on Route 1 to Kittery, where a multitude of popular outlet stores makes this a key stop for shoppers. Kittery is also home to the historic community of Kittery Point, which served as a summer destination for many respected 19th-century artists and writers, including Samuel Clemens (Mark Twain).
Pick up 95 South in Kittery to complete your trip. Thank you for visiting! Come back again.
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Trial of Laparoscopic Compared to Open Inguinal Hernia Repair in Children Younger Than 3 Years
Recruitment status was: Recruiting
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Laparoscopic techniques have been applied widely to the management of various common pediatric surgical diseases. Current evidence lacks sufficient quality to justify the widespread adoption of the laparoscopic approach to the repair of inguinal hernias within children. It is important to critically evaluate the efficiency and the potential risks of these new techniques before they can supplant open techniques as the treatment modality of choice. Numerous large case series of laparoscopic inguinal hernia repair have been reported with average length of stay, complication rates, recurrence rates and pain management scores that mirror those of open inguinal hernia repair. Only one randomized controlled trial has been performed to compare the open versus laparoscopic technique which has not provided answers regarding the potential benefits on young infants. Benefits of an open approach in children includes a shorter operative time, while the laparoscopic procedure is associated with less pain and a better cosmetic result.
This study will compare open versus laparoscopic repairs of inguinal hernias. The primary outcome variable will be total dose of acetaminophen administered postoperatively for pain management. Secondary outcome variables include 1) Incidence of intraoperative complications such as compromise of testicular vessels, perforation of abdominal viscera; 2) Short-term outcomes such as operative time, rate of conversion from open to laparoscopic procedure, requirement for reoperation within 30 days, wound infection, acute hydroceles and post-operative length of stay; 3) Long-term outcomes such as recurrent inguinal hernia, testicular atrophy and; 4) Cost of hospitalization will be compared between the open and laparoscopic groups.
Comparisons will be made in two groups of patients- patients with 1) unilateral hernias and 2) bilateral hernias and will last for 2 years. 102 patients in the unilateral arm and 50 patients in the bilateral arm will be randomized to each treatment group and each subject will be followed for up to 12 months following the surgical intervention. Two study evaluations by telephone (in addition to a single outpatient clinic visit already required as part of standard post-operative care) will be required of each research subject and his/her parent/guardian. The telephone evaluations will occur at 3 and 12 months following surgery. The standard post-operative clinic visit is scheduled at 2 weeks following surgery.
|Inguinal Hernia
|Procedure: Laparoscopic Inguinal Hernia Repair Procedure: Open Inguinal Hernia Repair
|Study Type:
|Study Design:
|Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Participant)
Primary Purpose: Treatment
|Official Title:
|Randomized Controlled Trial of Laparoscopic Compared to Open Inguinal Hernia Repair in Children Younger Than 3 Years of Age
- The primary outcome variable will be total dose of acetaminophen administered for pain management. [ Time Frame: 2 years ]
- Incidence of intraoperative complications: compromise of testicular vessels, perforation of abdominal viscera. [ Time Frame: 2 years ]
|Estimated Enrollment:
|Study Start Date:
|October 2007
|Estimated Study Completion Date:
|June 2014
|Estimated Primary Completion Date:
|January 2014 (Final data collection date for primary outcome measure)
|Assigned Interventions
|Active Comparator: Laparoscopic Inguinal Hernia Repair
Procedure: Laparoscopic Inguinal Hernia Repair
Laparoscopic Inguinal Hernia Repair
|Active Comparator: Open Inguinal Hernia Repair
Procedure: Open Inguinal Hernia Repair
Open Inguinal Hernia Repair
|Ages Eligible for Study:
|up to 3 Years (Child)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Age less than 3 years (36 months) at the time of surgery
- Reducible inguinal hernia
Exclusion Criteria:
- Concomitant need for other intraabdominal procedure
- Prior inguinal hernia repair procedure
- Hospitalization expected to be prolonged due to a concurrent illness actively being treated (e.g. congenital heart disease requiring surgical repair during the same hospitalization)
- Liver Disease or contraindication to Tylenol, Midazolam, Fentanyl, or Marcaine.
- Irreducible inguinal hernia, as determined in the operating room prior to randomization and incision.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00716768
|Contact: Fizan Abdullah, MD, PhD
|United States, Maryland
|Greater Baltimore Medical Center
|Baltimore, Maryland, United States, 21204
|Contact: Jeffrey Lukish, MD 410-955-5210 firstname.lastname@example.com
|Principal Investigator: Jeffrey Lukish, MD
|Johns Hopkins Hospital
|Baltimore, Maryland, United States, 21287
|Contact: Fizan Abdullah, MD, PhD 410-955-1983 firstname.lastname@example.com
|Contact: Misty Grimes 410.955.1983 email@example.com
|Principal Investigator: Fizan Abdullah, MD, PhD
|Principal Investigator:
|Fizan Abdullah, MD, PhD
|Johns Hopkins University
|Responsible Party:
|Fizan Abdullah, MD, PhD, Associate Professor of Surgery, Johns Hopkins University
|ClinicalTrials.gov Identifier:
|NCT00716768 History of Changes
|Other Study ID Numbers:
|Study First Received:
|July 14, 2008
|Last Updated:
|January 31, 2013
Keywords provided by Fizan Abdullah, MD, PhD, Johns Hopkins University:
Inguinal Hernia
Additional relevant MeSH terms:
Hernia, Inguinal
Pathological Conditions, Anatomical
Hernia, Abdominal
ClinicalTrials.gov processed this record on September 21, 2017


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I hate when life interferes with my reading, but I was finally able to read Chris Pavone's The Expats (Crown, Mar.). In my early days as a mystery junkie, I read a lot of spy novels—Ludlum, le Carré, etc.—so I feel qualified to say I loved this debut. The intricate plotting and use of alternating time lines propelled me through the clever story line, while the immersion into the covert world had the feel of an insider's view. When the fascinating Kate Moore—wife, mother, and spy—moves to Luxembourg with her husband, she begins to put her past behind her. But the couple's new life turns into much more than either of them could have anticipated, forcing them to face the complexities of truth in their marriage. Their dreamed-of new existence slowly unravels, taking turns that neither of them—or the reader—could have anticipated. For me, the story's compelling aspect was Kate, as she was being drawn back into her past life and doing whatever was necessary to protect her family. In a word, exceptional.
Volume 259 Issue 07 02/13/2012


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FORMER Accrington cricket star Ashar Zaidi has been told to 'korma' down by his new bosses and ditch his daily helping of curry.
The spin-bowler has been put on a strict diet and training regime – which means he can't enjoy his favourite dishes as often.
The 32-year-old admits he was out of shape when Sussex plucked him from Lancashire League cricket and offered him a route back into the first-class game last September.
And he said missing his daily curry is driving him 'jalfrezi', although he is feeling fitter than ever.
He said: "I was eating Asian meals which have a lot of carbs and calories, so I have had to make changes.
"I have to cut down and had to sacrifice having curries for salads.
"I do miss them, but to burn all the calories I would have to go another half an hour in the gym."
Ashar played for Accrington for three years, and helped them to the Foster's Lancashire League last season.
He proved popular and also played as a sub professional for Ribblesdale League sides Barnoldwick and Padiham during his time in East Lancashire.
Church signed Zaidi as their professional for 2014 but county side Sussex then offered him a two-year contract, which he accepted.
Ashar said: "Sussex is fantastic. I have always wanted to get back into the first-class set up.
"I'm thankful to Accrington for giving me the chance to play for them and perform."


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Future U.S.-Iran Trajectories Through the Lens of Former Hostages (2013)
An Evening of Dialogue with two former hostages of Iran from the 1979 takeover of the U.S. Embassy in Tehran
21 May 2013
5:00 p.m. – 7:30 p.m.
AAAS Headquarters
1200 New York Avenue, NW
Washington, D.C.
On November 4, 1979 a mob of Iranian students and militants supporting the Iranian revolution stormed the American Embassy Tehran, taking seventy Americans hostage. In what was to become one of America's defining diplomatic crises, the hostages were held in Iran for four hundred and forty-four days.
The Iranian hostage crisis—which was recently sensationalized for the American public in the film Argo—has had a deep and enduring impact on the next thirty years of the U.S.-Iranian relationship. In a conversation moderated by Dr. Norman Neureiter of AAAS, former US diplomats and hostages, Ambassadors Bruce Laingen and John Limbert, will talk about their internment in Tehran, their ultimate release, the truth and Hollywood behind the film Argo, the current nuclear standoff between the U.S. and Iran and share some surprising views on how one might deal with Iran today. Reception to follow.
Day of Event:
Enter at NW corner of 12th and H Streets
Washington DC 20005
Registration: 5:00 p.m.
Program: 5:15 p.m.
Reception: 6:30 – 7:30 p.m.


text:
Johnson, Rays take their pitches against O's
BALTIMORE -- Rays hitters saw 187 pitches in Tuesday night's loss to the Orioles. It was the 57th time in club history they had seen that many or more pitches in a nine-inning game but only the eighth time that they lost.
The Rays saw 11 full counts, and Kelly Johnson saw 35 pitches in his five at-bats, which produced a strikeout on 13 pitches, two walks, a home run and a groundout to third.
Johnson did not seem to be as impressed by what he had done as others were.
"You can't go up there saying, 'Today I'm going to see 30 pitches plus,'" Johnson said. "You might be 0-2, two heaters you could have handled every at-bat because you thought about taking. It's just not the mentality you want to have."
Johnson said a lot of walks come when hitters were doing well and the pitchers were pitching to them more carefully than normal.
"They think you're on everything," Johnson said. "So they just start trying to make perfect pitches."
Johnson also noted that when a hitter has an at-bat in which he sees a lot of pitches, he has missed some pitches he should have hit.
"Like that 13-pitch at-bat I ended up striking out, but I also missed three pitches I should have hit," Johnson said. "By not putting those in play and fouling them off, you get 13 pitches."
Bill Chastain is a reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.


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Research Admin 101
Designed for faculty and staff who anticipate submitting grants or contract applications through Saint Louis University. The session provides a very basic overview of the submission process, responsibilities of the principal investigator, compliance issues and a demo of the required eRS system through which all grants and contracts must travel in order to receive University review and approval prior to submitting to an external sponsor or agency.
Fusz Hall Conference Room
Noon - 1 p.m.
Past Workshops
The ONE Series: Opportunities for Networking Experiences
Substance Abuse/Prevention
3:30 - 5 pm Thursday, October 18, 2012
Boileau Hall
SLU North Campus
38 N. Vandeventer Ave.
Grantsmanship Boot Camp Series
Succeeding in any competitive endeavor requires advanced planning, strong technical skills, good coaching, expert advice, the resilience to bounce back from defeat, and most importantly, the willingness and dedication to put forth the effort to excel beyond one's field of opponents. Nowhere is this more true than in today's ultra-competitive funding environment that characterizes academic research and scholarship. This intensive four-part educational series assembles an armory of practical information and advice to best prepare SLU's "new recruits" to successfully secure funding for research and scholarship. The program features a seasoned faculty of funded investigators and research administration professionals to guide you in the development of persuasive proposals that stand out from the crowd.
Session I: Laying the Foundation: Preparing Your
Funding Strategy
3:30-5:00 p.m. Thursday, September 27, 2012
Busch Student Center 253
In this introductory session, learn how to tackle those areas
requiring advance planning that are critical to your overall
- Map out your funding strategy to align with career goals
- Distill/Elucidate your research idea
- Identify collaborators
- Identify resource needs
- Conduct a funding search
- Find a mentor
Session II: Making the Pitch: Engaging Reviewers,
Telling Your Story, and Establishing Credibility
3:30-5 p.m. Wednesday, October 10, 2012
Learning Resources Center, Room 113 (Med Campus)
Standing out among the crowd of applicants will depend upon how effectively you convince a sponsor that your research idea meets their mission and that you are the most qualified investigator to carry out the research plan. This session will focus on the art and science of persuasive writing, specifically tactics that will catch the eye, and not the ire, of a reviewer. Learn ways to 1) communicate the compelling significance of your project, 2) demonstrate control over its implementation, and 3) enhance the reading experience for the reviewer, using formatting and writing style.
Session III: How Much Will This Cost?
Developing and Justifying Realistic Budgets
3:30-5 p.m. Wednesday, October 31, 2012
Busch Student Center 253
A poorly crafted budget can torpedo even the most well written proposal. Learn how to accurately translate your project scope into a reasonable and allowable budget that partitions costs into the standard cost categories that meet agency and university guidelines. Office of Finance staff and funded faculty will be present to answer questions.
Session IV: Pulling It All Together: Submission,
Award Acceptance and Dealing with Rejection/Resubmission
3:30-5 p.m. Wednesday, November 14, 2012
Busch Student Center 254
- Subawards
- Submission tips
- Just-In-Time issues
- Award Acceptance
- Rejection/Resubmission
An Inside Look...
...at the Centers for Disease Control & Prevention (CDC) and the Health Resources & Services Administration (HRSA)
Postponed Until January 2013
The missions of the CDC and the HRSA intersect in their
goals of supporting health equity, leadership, and training. Both federal agencies fund research, workforce development, and other programs that build safe and healthy communities. This discussion will feature SLU faculty who will share their experiences as successful applicants, peer reviewers, and former agency administrators, guiding others in preparing competitive applications to the CDC and the HRSA. Panelists will share their thoughts on the qualities of "fundable" proposals and the review process. Discussion will also highlight Special Interest Projects (SIPs), a cross-agency funding mechanism targeting key areas of health promotion and disease prevention.
...at the Department of Defense (DOD)
Navigating research funding opportunities within the Department of Defense can be a daunting task. Supplying 50% of all federal research funding dollars, DOD is a relatively unchartered territory at Saint Louis University. Join us in an exploration of DOD resources and gain a topdown understanding of where to begin this journey.
ORDS can present on any of these topics at regularly scheduled departmental meetings or specific dates and times convenient for faculty. Contact us at 977-7742 to arrange a presentation time and topic.
By Discipline
By Career Stage
Archived Programming
"An Inside Look..." Sponsor Series
General Grantsmanship
Funded investigators offered recommendations for applying to both Midwest Affiliate and National Programs. Panel chair will be fresh from the latest review session just a few days ago! A newly funded predoctoral fellowship applicant was also be on the panel, so students interested in funding should also view.
Budget Development Presentation
Sample Budget Exercise Document


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Chocolate mud pie
Chocolate mud pie
Making mud pies is always good fun for kids of all ages. Now you can bring the fun indoors and get your kids cooking up chocolate mud pies in the kitchen. This no-bake recipe is very easy to make and even more delicious to eat!
- 250g pkt plain sweet biscuits (I used Arrowroot biscuits)
- 175g butter
- 2 tbsp cocoa powder
- 125g caster sugar
- 125g raisins
- 80g milk chocolate
- 3 tbsp chocolate sprinkles
- Break the biscuits into small pieces. Set aside. Melt the butter in a small saucepan.
- Take the saucepan off the heat and add the cocoa and sugar.
- Add the biscuit pieces and raisins to the butter mixture and combine thoroughly.
- Line a round cake tin with foil.
- Pour the mixture into the tin and press down firmly.
- Cover with foil and refrigerate for at least 2 hours.
- Break the chocolate up into small pieces in a small bowl and melt over a bowl of boiling water.
- Turn the pie out onto a serving plate.
- Pour the chocolate over the pie and spread across the surface evenly.
- Scatter the chocolate sprinkles across the chocolate. Leave to set.
- This no-bake mud pie is great fun for little kids to help make because you don't have to worry about the oven at all.
- You could turn this into mini mud pies and refrigerate the mixture in paper cases in a muffin tray.
- This is pretty messy to eat! It does crumble a little too when you cut it into slices so this is a great one to eat outside!
- This recipe was created by Ella Walsh for Kidspot, Australia's best recipe finder.
- Use plain sweet biscuits (I used Arrowroot biscuits).


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Gary, a native of Elkhart, spent the bulk of the last five years in Albuquerque, N.M., where he went as University of New Mexico coach Steve Alford's first recruit on his journey west.
Gary, who played at Concord High School, was a pivotal player in Alford having immediate success at New Mexico. But Gary's senior season in 2010-11 ended late in the season with a torn anterior cruciate ligament. It was a tough time, and forced Gary to miss his first would-be pro season while rehabilitating.
After working back into shape, he entered the NBA Development League draft and was selected in the first round by the Los Angeles D-Fenders. In a trade that was discussed prior to the draft, the D-Fenders shipped Gary to Fort Wayne in exchange for big men Jarrid Famous and Darnell Dodson.
In a few practice sessions with the Mad Ants, Gary has already met some high expectations. He is challenging for the point guard spot with veteran Walker Russell Jr. and Dante Williams, who was signed after an open tryout.
"We knew he was good," Mad Ants coach Duane Ticknor said. "He's better than we anticipated."
The plan is that Gary can join Russell in giving the Ants two quality point guards. At 6-foot-1, 205 pounds, Gary is bigger than the 6-foot, 170-pound Russell.
Ticknor said he feels Gary would be able to run the Ants well.
"If Walker gets called up or goes overseas or hurts his hamstring, whatever, we know we have a solid player there," Ticknor said. "(Walker) has had to pick it up in training camp. He isn't able to coast. Those other guards are pushing him to the limit.
"Williams is a free agent we picked up at the open camp in Detroit. He's very athletic. He just doesn't have quite the understanding those two guys do. Walker and Dairese can flat-out run a team."
Gary said he suffered the usual frustration of a knee injury, wondering when and if he could get his game back on track. He worked out regularly to strengthen his leg and feels ready to embark on his pro career a year later than he originally hoped.
"I'm doing real good," Gary said. "I got out of my brace a little bit ago and I've been working back up to things. I'm anxious to test it and see how good it really is. …Coach Alford and my teammates put me in a good position to go play at the next level after college. The knee set me back, and I had a few problems, but I'm back now."
Gary is back home again, and cold again, in Indiana. As long as he stays hot in the gym, his career can pick back up where it left off.