text:
Change to a custom domain
You can buy a custom domain and use that as the domain for your blog instead of ".blogspot.com".
Buy a domain from Google Domains
If Google Domains supports your country:
- Sign in to Blogger.
- Select the blog to update.
- In the left menu, click Settings > Basic.
- Under Publishing, in "Blog Address," click Buy a domain.
- Search and choose a custom domain.
- Next to the domain you choose and its price, click Buy.
- Follow the steps to complete your purchase.
Learn how to use Google Domains with Blogger.
Manage these domains
To see billing settings:
- Sign in to Google Admin. If you purchased the domain recently, your administrator account may be firstname.lastname@example.com.
- Click Billing.
- Next to your Domain Registration subscription, click Options
- Select Access billing account.
- Verify your billing information.
Recover your password for your Google Admin account.
Note: Change your username to a name you can remember.
Set up your domain with your blog
Set up a custom domain so that your original Blogger address automatically forwards to your new domain.
- Sign in to Blogger.
- Select the blog to update.
- In the left menu, click Settings > Basic > Publishing.
- Under your current domain, click Set up a 3rd party URL for your blog.
- Enter your URL, including the www.
- Click Save.
- An error will appear with two CNAMEs.
- Visit your domain registrar's website and find the DNS (Domain Name System) or the Name Server settings in the control panel.
- Delete existing CNAME entries.
- Enter the CNAMEs provided in the error message and click Save.
- Wait for a few hours for your settings to activate, then follow steps 1–6 above.
It may take up to 24 hours for the process to complete. If you see an error after 24 hours, try the process again. Contact your domain registrar for further help.
Host Name/Alias:
This is the part of your website's address that you designated. For example, if www.mydomain.com is your address, enter www.
<YOUR DOMAIN>.ghs.googlehosted.com
For example, if you chose www.mydomain.com as the address, enter
Optional: You can also enter A-records, which link your naked domain (example.com) to an actual site (www.example.com).
Enter your domain name in the format example.com, and list the IP addresses shown below in the "A" section. You'll need to add four separate A-records which point to four different Google IPs.
- 220.127.116.11
- 126.96.36.199
- 22.214.171.124
- 184.108.40.206


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Happy Free Shipping Day!
Free Shipping makes us happy! Not much compares to the convenience of doing your comparison shopping online being able to stack up coupons and cash back, and having everything delivered to your doorstep. But you don't want to spend that money you saved with your coupons and cash back on shipping, do you?
Getting a deal that also stacks Free Shipping can add up to really big savings, especially during the holidays when we're shopping a bit more than usual.
Here on FatWallet we offer several ways of finding Free Shipping deals.
- When on the Coupons, Sales or Product Deals pages, you can click the free shipping button to view only the offers that include free shipping.
- You can also sign up for Amazon Prime, for an annual fee of $99, which gives you free 2 day shipping. I know a few people who sign up for the Free 30 Day Amazon Prime Trial just for the holidays, although I use mine year round! Amazon also offers free shipping with a $35 purchase. There were some tips on ways to save on shipping charges at Amazon discussed in the FatWallet forums.
- A ShopRunner subscription ($79 per year $8.95 per month) also gives you free 2 day shipping at many stores. Watch for ShopRunner deals in our forums! They have an ongoing 30 day free trial for new members, but longer free trials do pop up from time to time on Fatwallet!
- Many stores will also give you free shipping with a minimum purchase.
- Free Shipping Day is December 18th this year, where hundreds of merchants will offer free shipping with guaranteed delivery by Christmas. We will have all the stores listed on FatWallet for you so you can take advantage of it to finish your Holiday shopping!
In order to help save you money and time this holiday season we've rounded up a bunch of the free shipping offers here on the blog for you as well. The list includes any minimum purchase requirements to get Free Shipping, dates that Free Shipping will expire if we have them, and the Cash Back if you shop through FatWallet. Remember cash back amounts and store policies can change.
Check them out below and happy shopping!
If you're going Oh S*@% because you haven't finished (or started) Christmas Shopping, here's a roundup of stores offering free shipping and the last day you can shop online and get Christmas delivery.
|Store Name
|Minimum $ Order for Free Shipping
|Order by Date for Guaranteed Christmas Delivery (Standard)
|Apple Store
|Free 2 Day Shipping on All Orders (Order by 5pm EST)
|12/18: Free Shipping No Minimum! Promo Code: FREE SHIP$75+ Use Coupon: FREESHIP75
|Best Buy
|$35+ (Free 2 Day shipping on thousands of items) Free Store Pickup
|Free Standard Shipping on All Orders (Exp. 12/22/14) Free Store Pickup
|$25+ on all in stock orders (Exp. 12/24/14) Free Store Pickup
|Home Depot
|$45+ on all in stock orders, Free Store Pickup
|$49+ free shipping anywhere (Exp. 12/20/14)
$25+ free shipping to store
Free Store Pickup
|$50+ (ends 1/1/15)
|$49+ (Order by noon ET 12/19 for christmas delivery) Free In Store Pickup
|$99+ (Free Returns)
|Free Standard Shipping on All Orders (Free Returns)
|Old Navy(Gap, Piperlime, Banana Republic, and Athleta)
|$50+(All Piperlime orders ship for free)
|$59+Free Store Pickup
|Free Shipping with Staples Rewards
|Free Shipping on All Orders (Exp 12/20)Free store pick up
|12/18 only: Get 25% off plus free standard shipping on orders of $40+ with coupon: USGETIT
Stores Participating in Free Shipping Day, December 18, 2014
Stores Offering Free Shipping All the Time with No Minimum Purchase:
- Ashford
- Apple Store: (iPods, iPads and iPhones)
- Blue Nile
- Estee Lauder
- Fresh Pair
- Kate Spade
- L. L. Bean
- Lacoste
- Linens 'n Things
- Lucky Brand
- Musicians Friend: (free std, flat $4.95 3-5 day ground)
- Nordstrom
- Piperlime
- ShoeBuy
- ShoeMail
- Shoes.com
- Sports Authority: (shoes and clothes)
- Sunglass Hut
- Target: (all online orders through Dec. 20, 2014)
- The Body Shop
More Stores Offering Free Shipping with a Flat Rate or Minimum Purchase
- Amazon: Free over $35 Amazon Prime / FREE 2 day shipping for members ($99/year)
- Ann Taylor: $8.95, Free with $175+
- Banana Republic: $7, Free over $50+
- Best Buy: Free over $35
- Children's Place: $5
- Drugstore.com: $5.95, Free over $25
- Gander Mountain: Free over $50
- Gap: $7, Free over $50
- Kohl's: (free shipping for Kohl's Card holders + $10 Kohl's Cash w/$50+ purchases)
- Levi's: Free with $100+
- Macy's: $9.95, Free over $99
- Moosejaw: $5.95, Free over $50
- Nike Store: Free with $75+
- Old Navy: $7, Free over $50
- Overstock: $2.95
- Target: (see above) Free over $50 or free with Target Red Card purchases
- Sears: Free over $59
- Ulta: $5.95, Free over $50
- Urban Outfitters: $10, Free over $60
- Walmart: 6-9 day free shipping on order $50+

subset: commoncrawl


text: Interesting choice, and a good one. But with hindsight, we can say that those mid-carders which went over went on to have top title-holding careers in WWE (with the exception of Shelton Benjamin). For all Tyson Kidd's skills, WWE has never seemed keen on pushing him that way. I think Sandow going over Sheamus would be an upset, but also just believable enough. Their match recently was good. Wade Barrett or Antonio Cesaro getting a win on Cena would be nice to see too.


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NEW YORK ( TheStreet) -- Popular searches on the Internet include HSBC ( HBC) as the British bank has agreed to pay more than $1.9 billion to the U.S. over money laundering allegations. The amount marks the largest penalty ever paid by a bank. An investigation into the bank focused on the transfer of funds through the U.S. financial system from nations like Iran that are under international sanctions and groups like Mexican drug cartels. As part of the agreement, HSBC will reportedly admit to certain misconduct, but it won't be prosecuted further as long as it meets certain requirements, like strengthening its internal controls. According to reports, HSBC will pay $1.25 billion in forfeiture -- the largest ever for a bank, and $655 million in civil penalties. The U.S. Justice Department is expected to detail the settlement later Tuesday. The bank said it has scaled back bonuses from senior staff, spent more than $290 million on corrective steps and attempted to limit the amount of business it does with countries that could pose a high risk of financial crime.
Delta Air Lines ( DAL) is trending as the carrier purchased Singapore Airlines' 49% stake in Britain's Virgin Atlantic for $360 million. Delta and Virgin also announced a trans-Atlantic joint venture under which they will share costs and revenue on routes between Britain and North America. The two carriers will operate 31 peak-day round-trip flights between the U.K. and North America. Planned routes include nine daily round-trip flights from London Heathrow to New York City's John F. Kennedy Airport and New Jersey's Newark Liberty International Airport. The deal is a coup for Delta, as it gives the airline a more enhanced presence at Heathrow, Europe's busiest airport. Virgin is the second-largest carrier at Heathrow, where landing slots are difficult to acquire. Entrepreneur and Virgin Atlantic founder Richard Branson said he will retain his 51% stake in the airline. Branson founded Virgin in 1984, and Singapore Airlines bought 49% of the carrier for $965 million in 1999.
American International Group ( AIG) is another popular search. The U.S. Treasury Department said it has sold all of its remaining shares of AIG.
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text:
Help Save Our Supplies and Equipment
Save Seattle's Stuff – We need Help Now !
We are losing our storage space. Help save all the contributions and supplies that we now use and that will be crucial in the days to come. We need you .. any transportation, any location that can provide storage, or just a willingness to help pick, pack and carry stuff. Without your help Occupy Seattle will lose thousands of useful items and supplies.
If you can help in any way, post your name, what you might be able to do and any contact information that can be used to contact you on this event page https://www.facebook.com/events/149438631843538/


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For the inaugural edition of Tuesday Thrift Store Transformations (TTST when I get tired of writing the whole thing…), I thought I'd share with you how I'm actually using the .99 bulletin board that I made into a DIY Ballard Designs Monogram Burlap Message Board (featured in the 31 Days series).
I decided to change the ribbon and then hung it in my bathroom as a burlap jewelry organizer:
I felt the black ribbon was a bit too stark for our yellow-cream-white-and-green bathroom, although I think the monogram looks fine. A simple switch to a cream grosgrain and all is well in my color-coordinated world. I know – blech – but I can't help it.
I had actually been thinking for years of how to tastefully organize my jewelry so the pieces would be easier to find as well as not be all tangled together like the typical jewelry box. And as pretty as some organizers are, it just seemed a bit cluttery to me in our bedroom to have a bunch of hangers or frames full of jewelry on the wall.
But when I finished this message board and realized I didn't have a place (or a need) for a message board, I started looking all around our house to see where I could use it – or else it was going to be a gift.
For someone else whose name starts with a "J." A-hem.
Total light-bulb moment when I walked into our master bath and the empty wall space above our toiletries cabinet jumped out at me. It was the perfect size for this wall and was a place where not many people would see it.
With the addition of a few long pearl-topped stick pins to hold necklaces and bracelets the board was able to hold all the jewelry I wanted to access – and there's even space left over for more I might add in the future. The weave of the burlap makes it easy to add hanging earrings anywhere.
I've seen burlap jewelry boards a lot of places on the internet and many use knobs and pulls to hold the jewelry, but this is simple and uses what I had and, well, works for me.
Hopefully I'll actually wear this jewelry now that I can easily find it!
How do you organize your jewelry? {click to comment}
Sharing at: Fabulously Creative Friday, Weekend Wrap-Up, and Funky Junk Interiors


text:
Moderators: Timko, Fritz, Solty, Booter, Blake_T, Frank Delicious
JR wrote:Wow i've beaten in one Pro Destro and it flips a lot still having Wraith like fade so absolutely miles away from the straightest or straightest finishing disc i've seen. You most have trashed that Destro. How long did it take i mean it could be a while before you could replace it if you beat another one as much. Which could be hard to do with all the other drivers.
I was not joking about doing one disc rounds with all of those discs because it illuminates the strengths and weaknesses of different classes of discs but also each individual disc too.
D4 bombs.
daleh2013 wrote:Mark,
Well said.....I've only been playing about a year and I do play with a group. But, the person that's closest to me in age is 51...I'm 54. The rest are in their 30's and yes, 20's. Do they throw far? Yup... Do we play from the back tees? Yup... I don't have the distance because yeah, I'm older..and because of an unrepairable detatched bicep (from years of weight training) of my throwing arm but no matter. I can get it out close to 300 so I'll live with it. So, I've taken a different attitude about the whole deal. When I was younger I played a lot of "stick" golf...and hit the ball a mile. I played with some older guys and they destroyed me around the greens...their approaches and short game were phenomenal. So that's what I'm doing now...working on accuracy in approaches and putting. Also, since I can't throw an effective forehand because of the injury I have discs that I can move either way to compensate for it. In doing so my scores have dropped quite a bit so in my own way I'm keeping up with the kids. Besides, there's nothing more satisfying than seeing the look in their eyes when they have been bested by an old guy.
So, I guess I'm saying the same thing you are...."dance with who brung ya" and make the most of what you do have. Work on technique, accuracy, "trouble" shots and putting. Then, go out and surprise people!
Return to Body Conditioning and Injury
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Participating Stores
2x Reward Zone points on nearly all purchases
3x Reward Zone points if you spend $1000 or more
Don't miss out on Best Buy's Reward Zone Scavenger Hunt! Enter for your chance to win one of twelve $25 Best Buy Gift Cards to be awarded at each store or one of the 45 Grand Prizes - 50,000 Reward Zone points, worth $1000 in reward certificates - awarded nationwide!
Exclusive event offers (video games stuff bolded):
Free DSLR Bag with Select Nikon Camera. Plus, save $250 on Nikon D5100 DSLR camera with 18–55mm VR lens.
Best Buy Exclusive: HP ENVY TouchSmart Ultrabook with Intel® Core™ i5 processor, 14" touch-screen display and Windows 8.
15% Off all games and accessories for Wii U. Quantities limited.
Triple Reward Zone Points on all Dyson vacuums.
Get Your Activation Fee Back when you buy any Sprint handset, including Samsung Galaxy S III.
Save $30 or $50 on a Samsung Wi-Fi Blu-ray player or 3D Wi-Fi Blu-ray player.
Triple Reward Zone Points on ASUS Zenbook touch-screen Ultrabook™ with 3rd Gen Intel® Core™ i5 processor, 13.3" display, and Windows 8.
Double Reward Zone Points on Logitech Harmony Touch or Harmony 650.
Save $20 on any Western Digital router or hard drive $79 or more.
Save $10 on a Roku 2 XS or XD wireless digital media player.
Save $50 on Garmin nüvi 50LM GPS.
Free Bag with Select Sony Cameras. Plus, save $50 on Sony Cyber-shot WX100 18.2MP digital camera.
Save $80 when you buy TiVo Premiere HD DVR and TiVo Stream together.
Save $30 on select Sanus wall mounts. Some mounts only available in Magnolia™ stores.
Free Sonos Bridge Wireless Extender when you buy Sonos Play:3 or Play:5 wireless-ready music system.
Buy 2 Insignia™ LED Light Bulbs, Get 1 50% Off 40-watt equivalent or 60-watt equivalent.
Triple Reward Zone Points on Beats Mixr™ on-ear headphones. In black, white, or exclusive red color.
Double Reward Zone Points on Bose® SoundLink® Bluetooth Mobile Speaker II.
Free SanDisk Ultra 16GB microSD Card when you buy a GoPro HD HERO3 Black Edition Adventure Wearable Camera.
Get a $150 Gift Card and Xbox® 360 4GB Console with activation of select packages from Time Warner Cable (select markets). Best Buy gift card sent by mail. Xbox 360 4GB console available after installation of services.
Edited by Sway, 28 November 2012 - 02:27 AM.
Updating title/post with new info


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felixtibs wrote: I was unaware i was even leading with elbow, just trying to pull through in a straight line. But now that you mention it, I will try and enforce its role and smash through as MB puts it
Try to begin the arm acceleration later. After the rear of the disc has passed the right side. Or for snap exercising in the last 12-8" before the arm straightens out completely.
Beware that leading too much with the elbow may be hazardous. You're the person to ask this on this forum so here goes: Last spring I really tried to go overboard with leading with my elbow to the max for as long as I could force my elbow to go using full power. I managed it too well. It felt like my muscles bulged as much they could late in the elbow lead when the upper arm was straight towards the target with my torso facing 90 degrees left of the target. Right side pointing towards the target just like the upper arm. I tried to force the disc to go as close to my chest as possible and force the disc to stay in a straight line until the elbow chops. When the upper arm couldn't move forward any more thanks to full extension it felt like I hit a wall with my elbow based on how I felt in my right shoulder.
It was like I was trying to throw my arm away separating from the shoulder. In terms of physics I think that's what I was attempting without realizing it at the time. There was a huge tension in my elbow as all the force I had generated concentrated in my elbow that was bent as much is possible. All the momentum I had going really hurt for a while in my elbow before finally it opened enough to let the power out by dissipating it into the motion of elbow chop. The elbow didn't feel bad long because the muscles in my shoulder hurt much more and longer. Bothers me 6 months later minimally during a long field practice session using full power.
In medical terms what do you think happened to my shoulder? Stretching as the upper arm moved out fully and couldn't move forwards and the elbow didn't immediately give way in chopping open but did after a slight pause and in a most uncomfortable motion being twisted in an unconventionally tight motion. Or was it the abrupt stop of the upper arm reaching maximum extension that caused a shockwave in the muscles? Or just the shoulder muscles bulging beyond capability using full power to keep the disc maximally close the the chest and keeping the same line. Without help from leg and hip turning initially. They came along only after or simultaneously with elbow chop. Perhaps forced by the elbow not giving way first so the elbow stopping perhaps dragged my legs and hip along to twist to the right.
Something else? Thanks for your opinions.
I didn't go to see a doctor but just took some time off and played with caution and fewer throws than normally with field practice and warmed up and stretched twice as much. And toughed it out until slowly the pain's almost totally gone now.


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OAKLAND — A man shot to death while driving in East Oakland Wednesday night was identified by police Thursday as Francisco Rosas, 26, of Alameda.
The shooting happened about 8:05 p.m. at the intersection of Russet and Moorpark streets, just a few blocks from the San Leandro border.
An officer in the area heard gunfire and found Rosas in the car, which had stopped in the street. Rosas was pronounced dead at the scene.
Police believe Rosas was shot by someone outside the car and that his car continued on its own before stopping.
Police said Rosas used to live in Oakland, was married and had a 2-year-old daughter. It was not immediately known why Rosas was in Oakland.
Sgt. Randy Brandwood said a motive has not been established yet and no arrests have been made.
The killing was Oakland's 116th homicide of the year, six more than all of 2011 and the highest number since there were 125 homicides in 2008.
Police and Crime Stoppers of Oakland are offering up to $10,000 in reward money for information leading to the arrest of the killer. Anyone with information may call police at 510-238-3821 or a tip line at 510-773-2805 or Crime Stoppers at 510-777-3211. Tips can also be sent anonymously via text message. Test to 888-777 and include the words TipOaklandPD.


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This is a serious trade proposal
Paul George and Roy Hibbert for Derrick Rose. The Bulls would have the most intimidating front line in the league with Hibb and Noah and would get their SG of the future. We would be taking a risk but one that is worth it. This could make or break our future.
But this is in good fun because I know it would NEVER happen.


text: +-------------------------------------------------------------------------+ | TPWD News Release 20111017a | +-------------------------------------------------------------------------+ | This page contains only plain text, no HTML formatting codes. | | It is not designed for display in a browser but for copying | | and editing in whatever software you use to lay out pages. | | To copy the text into an editing program: | | --Display this page in your browser. | | --Select all. | | --Copy. | | --Paste in a document in your editing program. | | If you have any suggestions for improving these pages, send | | an e-mail to email@example.com and mention Plain Text Pages. | +-------------------------------------------------------------------------+ [ Note: This item is more than five years old. Please take the publication date into consideration for any date references. ] [ Media Contact: TPWD News, firstname.lastname@example.com, 512-389-8030 ] [ Additional Contacts: Bryan Frazier, Texas State Parks, (512) 826-8703, firstname.lastname@example.com ] Oct. 17, 2011 Ribbon Cut on Scenic, Historic Daingerfield State Park Northeast Texas Park Celebrates Opening after Yearlong Closure, Renovations DAINGERFIELD, TX--More than 500 visitors entered the gate to celebrate the grand reopening and ceremonial ribbon cutting of Daingerfield State Park, set in the backdrop of northeast Texas' Pineywoods autumn landscape. After almost an entire calendar year of closure for repairs and renovations to facilities and campgrounds, the park is once again hosting campers, anglers, hikers and nature lovers on its 500 acres, miles of trails, lake shore, and Civilian Conservation Corp-built cabins and pavilion. "It is a place for people from all over to enjoy," said Lou Irvin, mayor of Daingerfield. "My family has been involved in this area for a long time; I spent many a day out on this park's lake. And I hope my grandchildren can enjoy this park too. We are so excited it's open once again." The day's celebration activities included a ribbon cutting ceremony, guided canoe tours of Lake Daingerfield, a geocache tour and nature hike, a children's bouncy place inflatable slide, Operation Game Thief Wall of Shame trailer, the Latino Legacy trailer from Stephen F. Austin State University, live music and a food vendor. "Growing up around here, sometimes we don't always appreciate what we have," said Texas State Representative Bryan Hughes. "I'm so glad that this park is still here, now, stronger than ever. I know a lot of people have worked hard to get us here. Our part of East Texas is better off because this park is here and back online." Texas Parks and Wildlife invested more than $5 million in capital improvements to add full hookup campgrounds with water, electricity and sewer connections; three new restroom complexes; renovations to the CCC-built Bass Lodge and dining hall; a new wastewater treatment plant; state park store and more. Money for the repairs and improvements was appropriated from budgets of previous bienniums. "This park represents a lot to our community and region of Texas, and we are so glad to have it up and running again, serving the thousands of visitors who come here each year," said Daingerfield State Park superintendent John Thomas. "It really is a complete destination for outdoor recreation; it's got beautiful scenery, a lake with good fishing, camping, cabins and group facilities. And today's grand reopening event was a fitting tribute to a fantastic and historic park." For more information, contact Daingerfield State Park at (903) 645-2921, or visit the Web site at http://www.texasstateparks.org/. To book state park reservations in advance of your trip, contact the customer service center at (512) 389-8900. -30-


text:
Bloody Michonne Unleashed at San Diego...
McFarlane reveals that they will be offering an exclusive Walking Dead action figure at this year's San Diego Comic-Con. Available exclusively from Skybound Entertainment priced at $25, McFarlane Toys limited edition Bloody Michonne action figure features the blood-spattered poncho she wore upon her first encounter with Rick and the survivors. The figure comes with bloody versions of her signature katana sword and various implements of revenge including a power drill, hammer, pliers, and spoon. Features approximately 22 points of articulation. Packaging features new art The Walking Dead artist Charlie Adlard.
To insure your action figure collection, get in touch with Collectibles Insurance, the official insurance company of the Figures.com network. Say "Figures.com" to get 5% off your first term premiums.
To buy action figures, take a look at BigBadToyStore.com, RedfordFilms.com, Toynk.com, PastGenerationToys.com, BriansToys.com, ToyWiz.com, and MonkeyDepot.com.


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Don't miss out on a lower price on this hotel
Get an overview of this hotelHotel with pool next to Sacramento Old Town
Collecting Nectar Points
Special Offer: Book by 2 August 2017 and collect double Nectar points!
Simply enter your Nectar card number when you check out. Your points will be credited 35 days after you return from your trip.
*Terms and conditions apply.
Popular property highlights
Carriage rides and art
Vagabond Inn Executive Old Town is just off highway I-5 and half a block from the carriage rides of Sacramento's Old Town. The California State Capitol Building and Governor's Mansion are 1 mile (0.6 km) away, the Crocker Art Museum 2.5 miles (4 km). Guests can drive 7 minutes to the Sacramento Zoo.
Free daily breakfast
The hotel offers a free hot breakfast buffet and free limited parking. Guests can relax in the hot tub, work out in the fitness center, and take a refreshing dip in the heated outdoor pool.
Free WiFi, coffeemaker
Neat, homey guestrooms come with a desk and chair, plus a microwave and fridge. Guests can kick back with a satellite TV show on the 46-inch flat-screen TV. Free WiFi makes it easy to stay in touch with family and friends.Information missing or incorrect? Tell us!Opens in a new window
Vagabond Inn Executive Old Town
Renovations & Closures
- Spa tub
- Swimming pool
Hotel Amenities
Hotel Amenities
Vagabond Inn Executive Old Town welcomes guests to relax by an outdoor pool or enjoy the spa tub and fitness center. A free breakfast buffet is offered each morning. A business center, free WiFi and a meeting room are also available. One free parking spot is available to hotel guests per reservation; additional cars can park for a nightly fee.
Vagabond Inn Executive Old Town is a smoke-free property.
- Business center
- Outdoor pool
- Spa tub
- Free breakfast
- Free newspapers in lobby
- Fitness facilities
- Safe-deposit box at front desk
- Multilingual staff
- Number of floors - 3
- Coffee/tea in common areas
- Television in common areas
- Elevator/lift
- Computer station
- Pool umbrellas
- One meeting room
- Parking (limited spaces)
- Restaurant
- Free self parking
- Pool sun loungers
- Conference space size (feet) - 700
- Conference space size (meters) - 65
- Smoke-free property
- Number of buildings/towers - 1
- Free WiFi
Family Friendly Amenities
- Family Hotel
- Outdoor pool
- Free Wi-Fi
- Refrigerator
- Microwave
- Cribs/infant beds (complimentary)
Available in all rooms: Free WiFi
Available in some public areas: Free WiFi
Free self parking, Parking (limited spaces)
Room Amenities
- Free WiFi
- Free cribs/infant beds
- Connecting/adjoining rooms available
- Premium TV channels
- Premium bedding
- Access via exterior corridors
- Air conditioning
- In-room climate control (air conditioning)
- Phone
- Free local calls
- Refrigerator
- Microwave
- Private bathroom
- Free toiletries
- Hair dryer
- Shower/tub combination
- Iron/ironing board
- Daily housekeeping
- Desk
- Blackout drapes/curtains
- Satellite TV service
- Rollaway/extra beds (surcharge)
Where to Eat
Guests are offered a complimentary hot/cold buffet breakfast each morning.
Vagabond Inn Executive Old Town has a restaurant on site.
Nearby Things to Do
An outdoor pool and a spa tub are on site. Other recreational amenities include a fitness center.
The recreational activities listed below are available either on site or nearby; fees may apply.
- Golfing nearby
- Hiking/biking trails nearby
If you have requests for specific accessibility needs, please note them at check-out when you book your room.
- Accessible bathroom
- Roll-in shower
- In-room accessibility
Hotel Policies
Check-in time starts at 3 PM
Check-out time is noon
Payment types
Children and extra beds
- Children are welcome.
- Kids stay free! Children 18 years old and younger stay free when using existing bedding.
- Rollaway/extra beds are available for USD 15 per night.
- Free cribs (infant beds)!
- Pets not allowed (service animals welcome)
You need to know
Extra-person charges may apply and vary depending on property policy.
- The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation.
- Deposit: USD 100 per stay
Optional extras
- Rollaway bed fee: USD 15 per night
Hotel Name
- Vagabond Inn Executive Old Town
- Vagabond Inn Executive Old Town Hotel
- Vagabond Inn Executive Old Town Hotel Sacramento
- Vagabond Inn Executive Old Town Sacramento
- Vagabond Hotel Executive Old Town
- Vagabond Hotel Sacramento
We should mention
Children 18 years old and younger stay free when occupying the parent or guardian's room, using existing bedding. The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation.


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TALLAHASSEE, Fla. - Florida's Internet cafes will become illegal within the next week.
State lawmakers on Friday delivered to Gov. Rick Scott a bill that would ban the storefront gaming operations.
Scott, who was in Jacksonville on Friday, has until April 12 to sign the bill. The governor's office has already said that Scott supports the legislation, and Scott said he plans to sign it.
The ban takes effect immediately after Scott signs the bill.
Florida legislators voted overwhelmingly Thursday to approve the ban. It was a quick response to a scandal that led to dozens of arrests and the lieutenant governor's resignation last month.
The operations allow customers to play sweepstakes games that simulate slot machines. But the new law will also impact senior arcades around the state as well. That's because the bill bans arcades from handing out gift cards to winners.
Jacksonville Internet cafe owner Robin Rukab says she's not about to give up on her business and says lawsuits will more than likely be filed for Internet cafes to stay open.
"I invite Gov. Scott to come to our game room, my game room, and take a look at exactly what is going on here before he picks up his ink pen," Rukab said, "because he will find out that what he is hearing is not the case."
Rukab said the game rooms are legal, and the Legislature and governor are rushing to judgment. She can't believe that her business is being punished because of what others did.
By that, Rukab is referring to Allied Veterans of the World and the crackdown and arrests in its operations on tax evasion charges.
"He will be upsetting over a million voters in the next governor's race," Rukab said. "There are 1,000 to 1,500 sweepstakes rooms in Florida. There are hundreds of thousands of people whose lives are going to be affected. We are not talking about my businesses, we are talking about mortgages, electric bills, payroll security officers. Seven families in this business depends on this income just in this small game room."
One of those affected is Sasha Gordon, who will be out of a job.
"I won't have another job. I will be unemployed and will try looking somewhere else," Gordon said. "I'm in school, I have kids, and hunting for a job is really hard right now."
So what does Scott want to tell the owners who thought they had a legitimate cafe running, but instead will have people out of work?
"I think the House and Senate did the right thing," Scott said. "What they are going to stop is illegal gaming like what Allied Veterans was doing. They were involved in a multistate criminal conspiracy."
Copyright 2013 by The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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"Hi Donna. I'm in the lakewood/brick area and could meet you half way if you want to try a game of singles. I'm btwn 3.0-3.5, just a little rusty from not playing in a while. Let me know when you are free. I am…"
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text:
I wanted Willingham to join the Reds, but it looks like it won't happen this year.
The Nationals get right-hander Henry Rodriguez and minor league outfielder Corey Brown, according to Rosenthal (on Twitter). Baseball America didn't rank Brown among Oakland's top ten prospects earlier in the month. However, Brown and Rodriguez ranked 12th and 13th, respectively, when BA ranked the Athletics' prospects heading into the 2010 season.


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For various areas of the country, crop consultants and agronomists might want to point out the value of growing sorghum compared to corn, especially after the 2012 drought showed the heat and drought hardiness of sorghum compared to corn in general.
Dairy and cattle farmers who have suffered through feed shortages and skyrocketing forage prices due to abandoned fields, reduced acreages and lower yields of corn and alfalfa can probably see a fit for sorghum if more was available.
"The drought is underscoring the need for productive forage crops with lower water requirements and production costs," noted Alta Seeds in a news release. "Independent studies have shown forage sorghum saves farmers an average of $200 per acre in total production costs compared to corn silage."
Just as with corn, new sorghum hybrids are being developed and introduced yearly that have advantages over previous hybrids.
"Forage sorghum with the Brachytic Dwarf and BMR-6 combination can produce high yield and feed value equal to corn with a variety of uses including hay, silage and grazing," said Barry Lubbers, U.S. sales manager for Alta Seeds. "Sorghum's water use efficiency is one of its greatest strengths. Sorghum is a hardy, drought tolerant plant that can perform with up to 40 percent less water than corn.
"According to research published by Texas AgriLife Extension in 2001, BMR-6 forage sorghums will yield 1.75 tons of biomass per one inch of water applied, while corn will produce less than one ton per inch of water applied. For irrigated producers, greater water-use efficiency means pumping less water, reducing the cost per acre of the forage produced."
Mark Marsalis, an extension agronomy specialist at New Mexico State University, is also noted by Alta Seeds as saying forage sorghum is often a viable alternative to corn silage, especially in areas where rainfall or irrigation is limited. Marsalis released a recent paper stating the case for more growers to consider planting forage sorghum.
"Input costs can be considerably less with forage sorghum than corn," Marsalis is quoted as having said. "Silage growers can potentially save on fertilizer expenses when growing forage sorghum. Excellent yields (up to 30 tons/acre with conventional types) have been obtained with 200 pounds per acre or less of nitrogen, which is less than what is commonly put on corn for the same yield goal."
The seed company also contends sorghum seed costs approximately $15 per acre compared to corn in the $100 per acre range, including traits.
"Silage producers must face the challenge of growing adequate feed supplies with considerably less inputs than in the past," Marsalis continued. "The drought and heat tolerance of forage sorghum combined with the ability to resume growth after drought makes it an ideal candidate for silage systems in dry climates facing water supply concerns."
His research has shown that forage sorghum can produce comparable or better yields than corn when irrigation water becomes limiting or when growing conditions are less than ideal.
"Whether it's an irrigated or dryland farming operation, sorghum's adaptive nature, high production efficiency and versatility make it a valuable tool and the best choice for forage producers demanding a reliable crop that produces high quality feed," said Lubbers.


text:
Investment Management
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text: We provide curated solutions to all exercises of Real Numbers for class 10 maths. After going through the ncert solutions of these exercises, you will be able to clear the fundamentals on all topics easily and in a better manner. This will equip you entirely for the exams and score more marks.


text:
ROB Dean hasn't given up hope on one day defying the doctors but the injured Chippenham Town midfielder is prepared to be patient on his long road to recovery.
Dean was told by surgeons he would never play football again after the horrific knee dislocation he suffered against Hungerford Town in March.
The 24-year-old returned to Hardenhuish Park for the first time since his injury for Monday's game against Hungerford and was honoured with the supporters' player of the year award and £1,000 to aid rehabilitation.
Dean's teammates also clubbed together to buy him a video game console, with the team also wearing warm-up T-shirts emblazoned with his nickname and squad number.
"The amount of people that came up to me to wish me all the best was surprising really – you don't really get the chance to speak to as many people when you're playing, so it's really nice," said Dean, who lives in Swindon.
"I'm still getting messages through and when you're sitting down all day, it's nice to know that people are there for you. I knew (my injury) was a bad one when I was in hospital and I was just eager to know what the chances were.
"A friend had similar one and he played again but I kind of knew that mine was a bit worse, with the way that they were talking about it.
"They said at hospital that they wouldn't be able to tell me until after the second op but once they revealed the news, it was really hard to take and that was a bad day.
"In the few days after that, I came to terms with it a bit and I didn't really accept it but I just wanted to get on with walking and not thinking about playing.
"It's so far away anyway, so there was no point in really thinking about it. I want to get myself walking and month-by-month, set myself little targets.
"Then you never know – people have proven surgeons wrong and hopefully, down the line, I can be one of them. Never say never."
Dean, who joined Chippenham from Swindon Supermarine last November, had scored seven goals before his season was cut short and the midfielder says that he was surprised to be given the 'player of the season' nod from the Bluebirds fans.
He said: "It's nice but also surprising to be honest.
"I felt that I did okay but I thought I could've done better. I scored a few goals along the way, which helped, but I thought there were others that have done really well this season, like Griff (Alan Griffin), Guths (James Guthrie) and Tinds (Greg Tindle)."


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IT'S Molly's christening in tonight's hour-long EMMERDALE (7pm).
But hey, never mind, because Chas takes this as her cue to come off the subs' bench.
And Debbie, in turn, takes Chas's appearance at the church as her cue to kick off big-time.
"You're not having HER as a godmother after everything she's done?! Are you mad?!?"


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Meet Xena
Oakland Pet Adoption Center's pet of the week is Xena.
She is a 2-year-old domestic short hair cat. Her identification number is 276455.
The Oakland Pet Adoption Center is located at 1700 Brown Road in Auburn Hills. For more information, call 248-391-4100 or visit oakgov.com/petadoption.
Meet Emma
Emma is a 10 1/2-month-old, 25-pound Cocker/Beagle Mix born July 8 of last year, and is looking to find her forever home.
Her owner gave her up because of allergies. Her family tried everything and was sad when Emma had to leave. So now she is looking for a new family.
She likes kids and people. She gets along with other dogs. She likes to play and will make a great companion for a variety of homes with a fenced yard and kids over 5.
Visit http://www.petfinder.com/shelters/MI730.html to find more info about Emma and Making Miracles Animal Rescue.


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Tuesday morning's Levy County School Board meeting began with members doubting what they were hearing and ended with a unanimous vote to move forward on a new program aimed at improving reading skills by exercising the brains of students.
Superintendent Bob Hastings said Levy County students are not reading at the state average in any grade despite having reading coaches at every school and the implementation of a variety of remedial programs.
"We have got to do something different," he said.
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(Don't see this in the similar threads, and it's slightly different than the Chad Ford rumor...I'm sure the mods will merge if necessary...if so, sorry)
Jonathan Givony is bringing up the JO-to-Cavs, but it's unclear what the deal is.
It stops short of saying "JO & 11 to Cavs for Crap-on-a-stick", but it's not a big leap to infer that.-The Indiana Pacers are trying to dangle the #11 pick in hopes of being able to package it with one of their ugly contracts (preferably Jermaine ONeal). There is talk out of ONeals camp that he anticipates being trade to Cleveland at some point this summer, possibly in a deal involving expiring contracts such as Wally Szczerbiak and Eric Snow.
The Pacers dont want to give ONeal away for nothing, but the temptation of shedding his 23 million dollar contract from their cap figure (giving them substantial cap space to work with in July of 2009) may be too great to pass up. On Clevelands end, it makes sense for their ownership to spend the money it will take to try and appease LeBron James and show them they are making the efforts to put together a championship caliber team. Weve heard rumblings about this Cleveland/Indiana trade from a number of well-informed sources, so there appears to be at least some truth to it.
I'm wondering if there is a package that could get it done, but I'd want Cleveland's #19 back. The most pallatable might be Wally, Sideshow Bob, S&T Delonte West, & #19 for JO & #11 (+ maybe filler?).
This package has a large expiring (Wally), two serviceable young guys (Varejao & West), and we get back in the draft where guys we like will be more reasonable (CDR, Brandon Rush, etc.). It's a pretty crappy deal, but they all will be, and I'm wondering if TPTB have reached the point where they're just going to take the best offer available and be done with it.
I'm getting the feeling that the guys we really like won't be there at 11, and the people we'd probably take would be a reach, so moving back 8 spots wouldn't be a huge penalty...(well, at least not on top of the penalty we're already paying in terms of talent return because of JO's contract & injury history.)
I don't know...it's a beggar's choice...probably be best just sitting on him.


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I think it'd be much better if you seperate Indiana Pacers forum from rest of the NBA. After all this is a Pacers forum.
I mean something like this;
Indiana Pacers
Talk about Indiana Pacers
NBA Talk
Talk about other teams in the NBA
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I think it'd be much better if you seperate Indiana Pacers forum from rest of the NBA. After all this is a Pacers forum.
I mean something like this;
Indiana Pacers
Talk about Indiana Pacers
NBA Talk
Talk about other teams in the NBA
It's been discussed at least once before. If I recall correctly, the last time it came up, I was up for trying it that way, but it seemed like the majority of others didn't want to go in that direction.
I don't know if this has been brought up before, but how about some form of a "NO thanks" button? Just as you can see that some posters tend to have posts in which people thank them and you can pay more attention to them when they post, maybe the opposite could be true for those posters who continually post contentious stuff and you can partially gauge what they're saying but the number of "no thanks" posts they have.
Hey! What're you kicking me for? You want me to ask? All right, I'll ask! Ma'am, where do the high school girls hang out in this town?
A while ago, I temporarily switched from Thanks to a + and - system where x number of +'s literally highlighted the post in question, while y number of -'s would actually "bury" a post to where you would then have to click to even read it, but it was deemed too much trouble for the board.
I forget the exact reasons at the moment, but I think it was something like creating animosity, encouraging mob/gang mentality, that kind of thing.
I'm not in favor of anything that would invalidate someone's opinion like that. While it's true that most of the time it's not the opinion itself that offends but the way in which it's shared, the poster who gets ther posts "NO THANKED" or "buried" isn't likely to see it that way.
With a no thanks button, a Rep system, or a + - system you are practically asking for someone to overuse it like the thanking or thread rating in the past. I don't think ANY negative response should be available that doesn't at least require a reply in thread.
It makes it too easy.
You mean where you would click the - button and it automatically requires you to give a reason that all can read?
I suppose. I meant to say someone should at least be required to post a reply if they wanted their voices heard but your suggestion would also work, if its possible.
It'd require a reason, get the negative feedback point across and may not take up as much space as a post.
It would probably cause the same in thread bickering though.
There is already the ignore feature if someone is that put off by what someone is saying.
I would strongly discourage any sort of "negative rating" feature. It might sound like a nice way to discourage trolls on paper, but it could also become a very contentious part of the forum.
I don't want to sound like a pie in the sky idealist, but I feel like there's plenty of negativity in the world already. I like the positive reinforcement only aspect of the current setup.
Agreed. It really did not work out well when it was last implemented. Besides, PD has almost no problem with trolls, and compared to other internet forums, this place is Civility Heaven. The +/- system most benefits forums with severe trollage. Here the negatives would far outweigh any benefit.
You, Never? Did the Kenosha Kid?
Don't change a thing. Love it here. You're all good people.
hmmmm I see no one has told you about btowns' cellar yet ??
So Long And Thanks For All The Fish.
If you've done 6 impossible things today?
Then why not have Breakfast at Milliways!
By the way I think this forum needs a good facepalm smiley. Because when words fail to describe the dismay, there is always facepalm !
Fatal error: Allowed memory size of 67108864 bytes exhausted (tried to allocate 12 bytes) in /var/www/includes/functions_search.php on line 196
Getting the above error whenever I try to start a thread. Googled it.....supposedly a server config issue?
Anyway, I'm putting this here, because I can't start a thread for it.
[~]) ... Cheers! Go Pacers!
Ha ha.
I liked 'smallie bigs' better, tho.
[~]) ... Cheers! Go Pacers!
The only solution that I'm aware of is a work-around, which is to start your thread with a small title like "test", then once the thread is up, edit your title to what you want.
I've never figured out how to edit a thread title.
[~]) ... Cheers! Go Pacers!
Try clicking "Edit" for the first post of your thread, then click "Go Advanced". There should be a box with the thread title in it where you can change it.
Or if you're viewing the thread while browsing the forum it's in (where it is listed among the other threads), you can move the mouse just to the side of the text and double-click, which should change the thread title from a clickable link to a text-box where you can edit it, and once you're done you click off to the side again to turn it back into a link.
I would like to suggest a "sticky" to go under Indiana Pacers. It might be practical to start a sticky called "Pacers Tickets to buy, sell or give away." I know there are many of us that might be looking to sell or give away some of our season tickets that we cannot use, and there are some games that I might need extra tickets for. Also, notices for ticket giveaways or specials from the Pacers that people find can also be posted here. Might want to consider the pros and cons, but can't think of any cons at the moment.
I would like to suggest that the use of the words 'suck' or 'sucks' or 'sux' more than three times, in any combination, (unless it's within a Market Square thread discussing vacuum cleaners) should be grounds for banishment.
[~]) ... Cheers! Go Pacers!
Is there any way to get an "Agree to disagree" smiley or anything? That could be of very useful IMO.
That'd be fine, but I don't know what image to use. Suggestions?


text:
The Authentic Music Game Experience
May 22, 2013
In 2010, music video games in which users played along to rock songs using fake instruments experienced one of the greatest crashes in gaming history. That same year, Ubisoft released Rocksmith, a music game that lets you plug in any guitar and actually learn to play.
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Things are really busy at the Chamber. Summer brings so many fun things to do in Henry Co. Coming up on July 30 is the Harvest Showcase, and the committee for this great event is planning for bigger and better things.
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text:
Posted 5 years ago
(82 items)
This is a fun find, I got it at a local public library book sale (Los Angeles area) and I've found a lot of great info. In honor of the recently released 1940 US census, I thought it would be fun to share this. Since the census is yet un-indexed, you can only search by location/ address/ innumeration district, not by name. If anyone has relatives who lived in Los Angeles during the 1940 census period, but have NO idea how to find them in the 1940 census, I'll be happy to look in this directory for you. It lists names, spouse name, occupation, if the person is the homeowner, and of course, address. No phone numbers. Here's a link to my blog entry about this book, and you can leave me a comment if you need info: http://copycatcollector.blogspot.com/2012/04/collection-210-vintage-1941-los-angeles.html


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Jay gets another day to work on swing
WASHINGTON -- In an effort to give Jon Jay an extended opportunity to work on his swing, manager Mike Matheny kept the center fielder out of the lineup for a second straight day. Jay is utilizing the time off to spend extra time in the batting cage, where he is specifically focusing on the timing of his complicated swing, which includes a lot more movement than most players.
"If you have that much movement, you're going to be a streaky hitter," Matheny said. "When he's hot, I think he's as hot as anybody. And when he's cold, he could be the [opposite]."
To this point it has been the latter. Though Jay left Spring Training feeling good about his timing, he has found no consistent rhythm this month. In 18 games entering play Wednesday, Jay had batted .197 with 17 strikeouts and just three walks. It's hardly the start Jay raced out to last season, when he was hitting .400 at the end of April.
"Obviously, I wish I could be doing better, but I'm not," Jay said on Wednesday. "But at the same time, I know that this is a long season and you go through this as a player. I know I'm going to come out of it.
"I feel like this year, I've had games where I've been consistent and games where I haven't been. It's just a combination of things. When things are going bad, it's bad. I haven't lost confidence in what kind of player I am and what I can bring to the table. This happens to everyone. It's not fun when you're dealing with it in the beginning of the season."
Jay compared this current stretch to the one he endured last summer, shortly after returning from a shoulder injury. As he worked to get his timing back, Jay hit .197 over a 21-game stretch from June 24-July 20. He struck out 16 times and walked seven times in 72 plate appearances.
The struggles weren't so noticeable on the stat sheet because his early-season success masked the dip in batting average. And in the end, Jay finished the season with a .305 season average.
"Jon, you forget how young he still is in his career," Matheny said. "He's still trying to figure out those keys, those cues he has to have to get him back to where he needs to be. When he gets it, it'll be fun to have him back at the top of the order."
Jenifer Langosch is a reporter for MLB.com. Read her blog, By Gosh, It's Langosch, and follow her on Twitter @LangoschMLB. This story was not subject to the approval of Major League Baseball or its clubs.


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Moderators: Timko, Fritz, Solty, Booter, Blake_T, Frank Delicious
the_lung wrote:
And then you have the holes which are fine for Open & Masters, but have NAGS zones and are tweeners for Open Women, Masters Women and Senior Grandmasters divisions. But because of the potential for bruised egos, these divisions don't want to play different tees than the Open players, even though they are completely inappropriate and result in terrible scoring separations. But that is another topic altogether.
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text:
TULARE, Calif. — During the past decade, the demand for locally grown produce has grown to the point where it's now mainstream and is similar to the organic sector.
The trend created opportunities for many smaller, regional grower-packers, but also cut into the summer sales of some large California grower-packers by as much as 15%.
Those are two of the findings of a report released Feb. 14 by Rabobank's Food & Agribusiness Research and Advisory group.
Titled "Local Foods: Shifting the Balance of Opportunity for Regional U.S. Produce," it looks at how consumer demand for local produce has affected both regional and California production, and shifting retail perspectives.
"(Local produce) has reached critical mass," said Karen Halliburton Barber, assistant vice president, senior agricultural analyst and report author. "It's been going on for five to seven years in terms of being more of a mainstream trend."
Nevertheless, she said local produce has room to grow for at least the next five years.
A challenge in writing the report was defining "local," she said.
Sacramento, Calif.-based Raley's, for example, considers local anything grown within a 50-mile radius of their stores. Whole Foods defines local as anything within a seven-hour truck ride.
The buy local movement grew out of farmers markets and roadside stands as consumers wanted to connect with farmers and sought fresher, tastier produce that had logged fewer food miles.
In response, regional production exploded in several areas, including Oregon, Washington, Michigan, the Ohio Valley, Georgia, Florida, Wisconsin, New York, New Jersey and the Carolinas.
Much of the growth has come at the expense of the California summer produce season, where growers already had reduced acreage of some items, such as lettuce and broccoli, to counter seasonal production elsewhere in the U.S.
The effects vary among California operations.
"It's not affecting everyone the same," Barber said. "Some are not affected at all. Others maybe 10%. Still others, 15% of their annual sales were lost during the summer."
Many California grower-packer-shippers banked on their hard-won reputation for consistent high quality and safety, which distinguished their produce nationally, she said.
Some already are seeing a need to adapt and have worked with producers in other regions so they can ship from multiple areas and offer retailers more local products, Barber said.
Many retailers saw the buy local trend as an opportunity and began sourcing seasonally available produce within a closer proximity, she said.
They also saw it as a way to reduce transportation costs and possibly reduce their carbon footprint.
Some retailers have seen sales of locally grown produce increase by 50% during the past seven years, she said.
Even Walmart has gotten onboard and has set a goal of sourcing 9% of its overall produce locally by 2015, she said.
Many retailers also have used local produce to enhance their market position.
"They may already have ownership of that region, but they've used the trend to make that connection to the consumer stronger," she said.
But with the growth of the buy local movement also have come challenges.
Some smaller growers may have more difficulty meeting food safety requirements and they may not have the same distribution and logistics capabilities of larger-scale grower-packer-shippers, Barber said.


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Steve Bakunas, Linda Lavin and The Red Barn Studio Theatre Present POSITIONS NY Premiere, Now thru 10/21
The New York premiere of Owen Dunne's new play POSITIONS will be presented Off-Broadway this fall from tonight, October 10-21 at Roy Arias Studio Theatre (300 W. 43 St.) in Manhattan. With previews set for tonight, October 10 and a press opening scheduled for October 11, POSITIONS is presented by Steve Bakunas, Linda Lavin and The Red Barn Studio Theatre, where POSITIONS received its world-premiere this spring.
The cast of POSITIONS includes Mike O'Neil, Michele Gagliano and Anna Stromberg. The play is directed by Mr. Bakunas.
POSITIONS is an entertaining and provocative look at sexual dysfunction in a marriage: when Leo and Hilary's union begins to fail in the bedroom, Leo suggests they re-engage by trying "52 positions"—a different one each week of the year. What transpires is both playful and menacing as tables are turned in a clash between romance and desire.
Located in Wilmington, NC, Red Barn Studio Theatre is a 50-seat theatre—a converted garage/warehouse—renovated and opened by husband-and-wife Mr. Bakunas and Ms. Lavin in 2007. The theatre has presented 15 productions over five seasons, including DRIVING MISS DAISY, DOUBT, I AM MY OWN WIFE, BOSTON MARRIAGE, THE TALE OF THE ALLERGIST'S WIFE, LOBBY HERO, GOD OF CARNAGE, RABBIT HOLE, and COLLECTED STORIES.
POSITIONS is Mr. Dunne's first play, Red Barn's first world-premiere and its first production to transfer to New York. Mr. Bakunas has directed Red Barn's productions of GOD OF CARNAGE, LOBBY HERO, THE TALE OF THE ALLERGIST'S WIFE and COLLECTED STORIES.
POSITIONS will perform Wednesdays through Fridays at 8 pm, Saturdays at 2 and 8 pm and Sundays at 3 pm. Tickets are $20 and can be purchased by calling 212 957 8358. For more information, visit www.redbarnstudiotheatre.com.
Photo credit: Kelly Starbuck


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Yarn & Coffee looks like a quaint shack buried in the back parking lot of The Pantry. It's been a 10-year project for Deborah Grossman, who first conceptualized her own 'knit and coffee' shop in 2001.
Grossman began hosting "stitch 'n' bitches" at her house, an after-work convention of crocheters, knitters, sewers, one baker "and sometimes," Grossman says, "people just came to bitch."
During that period, Grossman was working in the IT department of a medical clinic. "I got laid off in September [2012], and I thought I could get another job in computers," but the alternative was too good to pass up.
There's a living-room ambiance to her café—sofas, rocking chairs, cupboards (stacked with hanks, balls and skeins of yarn)—and the first room, in particular, emanates the feel of a Cape Cod sunroom, with huge rectangles of glass that stream in light.
Knitting's been quite the trendsetter these days—a DIY venture that somehow has needlepointed its way into underground artistry.
In 2005, Houston, Texas' Magda Sayeg, along with a collective of fellow knitters, founded "Knitta Please," a radical yarn-bombing warfare that, rather than destruct public objects, embellishes them: trees, statues, poles, etc.
Knitta spawned a worldwide movement of, as they're called, guerrilla knitters, who continue to embellish public properties and, in one particular case, a Humvee M1026 (a blatant political statement by Santa Fe artist Shirley Klinghoffer, who dressed a Humvee vehicle in a 15-foot knitted cozy).
"It's about aesthetics," Kathyrn Davis says. Davis, alongside Eileen Braziel, curated Pretty Tough: Gender in 21st Century Artmaking, a very tactile exhibition that explores the masculine and feminine attributes of art.
Concerning knitting, Davis says, "It's stereotypically female."
Because knitting and crocheting was, in essence, an at-home craft—especially during Victorian times, when a proper lady needlepointed in the parlor while she waited for her gentleman caller to arrive—it's no surprise that when a knitter/crocheter is asked the inevitable, "Who taught you?" the answer is, most conventionally, "My mother."
When I first walk into Eileen Braziel's studio and shake hands with Davis and Braziel, Davis remarks, "Your hands are freezing!" Thirty seconds later, all three of us are lassoed up in a 30-foot crocheted shawl, crafted by Amy Schmierbach, an up-and-coming artist featured in Pretty Tough.
Schmierbach learned the craft from her mom and, ever since, has incorporated the hobby into her artistic trade.
In her gallery exhibitions, spectators are actually encouraged to touch the displayed pieces with signs tacked to the wall that read, "Please Touch"—an invitation to interact.
"I just want people to relate to the work," Schmierbach says. "Because," after all, "I can just wash it."
Originally conceived as a traveling show, Braziel and Davis' exhibition sought to represent the individual's intimate relationship to the art; an organic exploration—whether it's by the artist or the spectator—to touch and be touched by the exhibition.
"It's calming; it's cathartic. I know you're not supposed to say that about the art...but I think that," Schmierbach muses.
There's also something about knitting that promotes community.
Schmierbach gathers with her friends to knit and crochet—a productive hangout.
"You don't really see painting groups coming together," she says, "or ceramics coming together." But knitting, well, that's a different story.
That's why Grossman, mustering the balls (of yarn) necessary, is trading IT for Yarn & Coffee: a lifelong dream.
"I think people who knit and crochet like to congregate with other people who knit and crochet," she says. It's as simple as that.
Like Schmierbach, Grossman learned to knit from her mother, and so, the tradition continues. With a twist.
"I taught my son's class," Grossman says.
Yarn & Coffee opens Friday, Feb. 1, at 11 am. 1836 Cerrillos Road, 780-5030


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The FAA released Advisory Circular 120-76B late last week, updating the "Guidelines for the Certification, Airworthiness and Operational Use of Portable Electronic Flight Bags." Naturally, much of the interest surrounding the updated AC involves how it applies to tablet computers such as the Apple iPad, which has gained a huge following among pilots in all segments of aviation.
According to NBAA senior manager of finances and tax policy (and formerly part of the Operations Service Group) Scott O'Brien, "It's a safety-based document." The AC outlines processes that the FAA recommends for safely incorporating portable EFBs, including the recommendation for rapid decompression and non-interference testing and battery safety and backups.
Part of the AC is confusing, O'Brien explained, because while the document applies primarily to fractional and commercial operations, it implies that Part 91 operators of heavy jets should consider following the AC guidance as well because they must fly with current charts. O'Brien suggests that Part 91 operators using iPads or tablets in the cockpit "be prepared to document what your mitigation strategies are," even though this isn't required by regulation. "It's in your best interest to document what your plan is. Using the guidance here, you can do that pretty easily."
Doug Haughton (not verified)
June 13, 2012 - 4:14pm
Over the past 6 months I have incorporated a iPad into my flights, both IFR and VFR. In my near 40 years of flying I have yet to have the batteries fail on my paper charts.
Steve Kane (not verified)
June 13, 2012 - 4:19pm
Until we have fully capable aviation quality tablets, the best role for the iPad is as a back-up for panel instruments. Software has come a long way.
Don Coleman (not verified)
June 13, 2012 - 5:41pm
Most of my flights are over 900 NM and filed direct. The i-Pad serves as a back-up to a 530/430 combination. I download paper approach plates from AOPA before each flight for several alternates and the destination. If required to fly V airways, AOPA downloaded and printed log will give you ID, Freq. , distance and bearing for each WP. The probability of all of that failing at one time is so slight that it would be a very small % nummber. It is a much simpler and far less work than the huge bundle of paper that was needed when soley Jeppesen dependent. I also have a Garmin 186 with a synthetic GPS driven nav. panel mounted on the eybrow. This system has back-ups for the back-ups.
tom srachta (not verified)
June 13, 2012 - 6:06pm
Sorry to be an old guy but, I've heard all this stuff before every time a new piece of equipement comes out. Don't trust those VOR's, DME's are for lazy pilots, and how many times do you now hear how real pilots don't use GPS. Well, I can tell you that every new idea from multigrade oil to variable pitch propellers and V tails all had there issues and even problems until we learned to use them appropriately. I have the Garmin 750 (with NOS charts) and in the last 6 months I've added the Ipad and Foreflight with ADS-b WX even though I have radar and stormscope on board. I still take paper charts with me but it is not because the two electronic devices are going to fail but rather than this old pilot takes a little time to get used to new things. Use the stuff correctly for you - the world is going to change whether we like it or not.
thanks for taking the time to read this.
Eric Davis (not verified)
June 14, 2012 - 9:33am
If you fly over several centers more than a few times each year, the money saved not buying paper charts will let you buy two iPads. I personally recommend WingX but if you're really paranoid run WingX and Foreflight. If all that fails, tell ATC your situation. There's your backup!
William Blaylock (not verified)
August 20, 2012 - 9:34am
In two years of using the IPad for IFR and VFR, I have had no problems, using a Bad Elf GPS has only improved the pad. The updates are always there and no paper or books to deal with. When you need a chart it is there, the IFR's are great, but how much of a pain is having the VFR charts for a flight. On the IPad they are all at your fingertips. Being an "old guy" (57) this is the best thing to come down the pike in a long time. I was amazed with Arnav, then Loran and to have GPS and now a small portable pad that does it all with moving map on the charts that I can take from plane to plane.
Blake (not verified)
August 20, 2012 - 1:31pm
I think the airlines will benefit the most. Terms of paper cost and weight. United has come out with a savings of 16 million sheets of paper, and 326,000 gallons of fuel annually. Not mention to cost of printing related cost. For example, printer supplies, and maintenance.
source: http://www.prnewswire.com/news-releases/united-airlines-launches-paperle...


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Maldonado to keynote WUD convention
Western United Dairymen's (WUD) annual convention will be held March 5-7, at the Embassy Suites hotel, San Luis Obispo, Calif.
Former Senate Ag Committee chair Abel Maldonado will offer the keynote speech, March 6. Maldonado, well known for his California agriculture advocacy, is the eldest son of immigrant Mexican-American farm workers. Find other details on the convention can be found on the WUD convention website located at www.wudconvention.com/
The challenges and opportunities of federal and California milk marketing orders will be the topic of a panel discussion on March 6, 9:30 a.m. The panel, moderated by WUD CEO Michael Marsh, CEO, will include Dana Coale, Deputy Administrator USDA /AMS Dairy Programs, and attorneys Chip English, a partner at Davis, Wright, Tremaine LLP, and John J. Vlahos, Partner, Hanson Bridgett LLP. The complete agenda can be downloaded at www.wudconvention.com/agenda/
The WUD Convention hotel registration deadline to obtain the discounted rate of $129 has been extended to Feb. 14. Late reservations must still use the WUD group link/code (below), but will receive the best-available rate.
Online reservations: To automatically be added to the WUD room block and receive the discounted rate starting at $129 per night, go to: www.WUDconvention.com and choose the "Hotel/Location" tab to find the link to the Embassy Suites. Or, call 805-549-0800 and provide: 1) Check-in/check-out dates; and 2) Group name "Western United Dairymen" OR Group Code "XWU"
Convention registration forms are available on WUD's convention website: www.wudconvention.com/register-to-attend/ There are two registration forms: One for WUD members and invited guests, and one for non-members and exhibitors.
Source: Western United Dairymen
Emergency drought relief bill offered
Just days after Gov. Brown issued a drought emergency declaration, three California Congressmen, joined by House Speaker Rep. John Boehner (R-Ohio) announced an emergency drought-relief bill to help farmers through what is certain to be a devastating year.
If passed, the bill would temporarily halt restoration of the San Joaquin River designed to bring back the historic salmon flow, among other measures. The bill is expected to be introduced in two weeks. It calls for allowing farmers to pump from the Sacramento-San Joaquin Delta as water permits and forms a House-Senate committee to tackle water troubles. The bill's three main prongs would seek to increase pumping out of the delta – if water is available – to agreed-upon 1994 levels, suspend the San Joaquin River restoration settlement, and create a Senate-House task force to come up with long term solutions.
Boehner was joined by three Republican colleagues: Rep. Devin Nunes of Tulare, Rep. Kevin McCarthy of Bakersfield and Rep. David Valadao of Hanford.
The proposed bill ran into immediate opposition from Sen. Dianne Feinstein (D-Calif.), who issued a statement saying: "I am concerned that (the new proposed bill) may follow the pattern of previous House bills which seek to either preempt state law or waive state water quality and Endangered Species Act requirements which could spur serious litigation and likely delay any action."
Source: Western United Dairymen
Commentary: California drought a fish story
Source: Rob Vandenheuvel, Jan. 24 issue of Milk Producers Council newsletter
As we approach the end of January with very little measurable rain to speak of in California, there is more and more talk about a California drought and the impact it is having on the residents and farmers of California's Central Valley. If you haven't already seen it in your paper or on your evening news, it will undoubtedly be there soon.
The general population outside of our state probably knows very little about the Central Valley of California, but they undoubtedly recognize the "Made in California" labels that are on many of the products they eat. Given the readership of this newsletter, you already know that California's dairy farms produce about 20% of the nation's milk. But did you also know that according to CDFA, nearly half of U.S.-grown fruits, nuts and vegetables come from California as well? Obviously, the availability of water in the Central Valley has a huge impact on U.S. availability of food (not to mention the global consumers of our products as well).
While much of the media attention has been on the lack of rain – which is certainly a valid observation – we as a local agricultural industry know that this drought was largely set in motion by human actions. No, I'm not talking about some theory that your pickup truck is causing "Global Warming." I'm talking about the fact that our federal policies have resulted in a higher priority being set on the well-being of a 3-inch fish over the well-being of millions of California residents.
A short 12 months ago, California authorities released 700,000 acre-feet of useable fresh water out of the Sacramento-San Joaquin River Delta, and into the Pacific Ocean. Haven't seen that in the media stories on this issue? Not surprising. If that fact seems preposterous and unbelievable, check it out on California's Natural Resources Agency's website: http://goo.gl/3j7vUy.
Was it because of a lack of storage capabilities? Absolutely not! It was because of a fear that if the water were pumped from the Sacramento-San Joaquin River Delta into available storage facilities, it might have killed some of the "Delta Smelt," a 3-inch fish that happens to be on the U.S. "endangered species list." Exactly how much water is 700,000 acre-feet? More than 260 billion gallons. And by the Natural Resources Agency's own admission, it's "enough to irrigate more than 200,000 acres of farmland or supply 1.4 million households for a year."
How much better off would we be if we had that 700,000 acre-feet today in storage?
In the coming days/weeks/months, there will be lots of talk about how we can prevent this in the future, and we greatly appreciate the leadership of our Central Valley Legislators in trying to bring national awareness to this issue. We look forward to working with them on both short and long-term solutions. But in the meantime, we are left living with the real-life, painful consequences of a ridiculous federal policy that literally chooses the welfare of a 3-inch fish over that of the human beings that live here.
Water quality funding available for Eastern San Joaquin River
The USDA Natural Resources Conservation Service (NRCS) announced that $3.5 million is available to California dairy producers east of the San Joaquin River in Merced and Stanislaus counties for water conservation and water quality improvements. This financial assistance is being made available through the Bay Delta Initiative (BDI), which was created in 2011 to help farmers in California's Central Valley apply enhanced water quality-improvement practices on their land through a multi-year process.
BDI is one of a dozen national initiatives aimed at assisting farmers to put added conservation practices on the ground using a landscape-level approach. Applications are due Feb. 21, 2014. For more information, contact the Merced and Stanislaus County NRCS offices.
Source: Western United Dairymen
California Ag Leadership Program seeks applicants for Class 45
Applications are now being accepted for Class 45 of the California Agricultural Leadership Program. Growers, farmers, ranchers and individuals working in allied businesses and organizations are encouraged to apply.
The Ag Leadership Program, operated by the California Agricultural Leadership Foundation (CALF), is considered to be one of the premier leader-ship development experiences in the United States. More than 1,200 men and women have participated in the program and are influential leaders and active volunteers in the agriculture industry, communities and other areas.
The 16-month program, from October 2014 to January 2016, is composed of monthly seminars delivered by Cal Poly Pomona, Cal Poly San Luis Obispo, Fresno State, UC Davis and other academic institutions. Fellows also participate in a 10-day national travel seminar and a 15-day international travel seminar. Seminars provide a comprehensive curriculum focusing on a variety of subject matter.
Detailed program information and the phase one application are online at www.agleaders.org. The phase one application is due no later than May 12, but individuals are encouraged to complete it earlier.
Source: Western United Dairymen
April 4 deadline for WUD Dairy Leaders Program applications
April 4, 2014 is the deadline to apply for Western United Dairymen's California Dairy Leaders Program. Designed to train the next generation of California's dairy leaders, the leadership program consists of several sessions devoted to developing a better understanding of the economic, legislative, marketing, and environmental issues facing the industry.
Eligible participants must be actively involved in milk production, be able to spend the necessary time in class, as well as studying resource materials, and be able to commit to visits to locations such as Sacramento and Washington DC. The program application process this year is being opened up to individuals in allied industries. Applications can be downloaded from the WUD website at www.westernuniteddairymen.com
The year-long program kicks off in the spring. Topics include environmental issues, the state and federal legislative process, dairy pricing and economics, biotechnology developments, marketing and promotion, and public relations skills. Participants will develop and enhance their leadership skills through communication, business etiquette, negotiation skills, time management, and team building workshops. Instruction will be provided by recognized experts in their field.
Class enrollment will be limited to ensure one-on-one instruction. The program enrollment fee of $750 should be submitted with letters of recommendation. Further information is available by contacting Western United Dairymen at (209) 527-6453.
Source: Western United Dairymen
Hoof health management courses offered March 4-6
A hoof health management workshop will be held at two locations in central California: March 4 in Tulare; and March 6 in Merced. The workshop is hosted by UCCE and sponsored by Micronutrients.
The same program will be offered in two locations. The program will be presented by Alfonso Lago, DVM, PhD, Dairy Experts.
Participants will have the opportunity to work with Dr. Lago and others to develop their skills trimming, blocking and wrapping hooves. Proper care and sharpening of hoof trimming tools will also be practiced.
Bovine lower leg anatomy, biomechanics, lesion identification and classification, functional and therapeutic hoof trimming practices, blocking and wrapping will be covered during classroom instruction.
The sessions will be held:
• March 4 – UC Davis Veterinary Medicine Teaching and Research Center, Tulare. Contact: Alex Souza at (559) 805-2639 or by email at: email@example.com
• March 6 – UC Cooperative Extension, Merced. Contact: Alejandro Castillo at (209) 385-7403 or by email at: firstname.lastname@example.com
Pre-registration of the $10 fee by Feb. 26 is recommended.


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With so many rappers idling towards upbeat, party-oriented tracks today, the more classic, sample-based Hip Hop albums have begun to fall by the wayside. Aware of this, rapper Planet Asia and producer Gensu Dean have put their heads together and concocted Abrasions. The 17-track collaborative effort can be seen as counter-effort to the more predominant and contemporary Hip Hop in 2013.
For Planet Asia, Abrasions is the veteran's fifth collaborative LP with one producer or production team. A true journeyman, he has made a name for himself over a span of more than a decade, having worked with dozens of artists from DJ Muggs to Talib Kweli. As for Gensu Dean, Abrasions carries a bit more significance: it is his first collaborative album under Mello Music Group, as well as his second release as a roster mate. Though his professional career is still relatively young, Gensu Dean has done well for himself over a roughly 10-year stint producing, having worked with artists like Brand Nubian, Large Professor and David Banner. In early 2012, he released his first album via Mello Music Group, Lo-Fi Fingahz.
Abrasions resonates with a strong, authentic grit. The album begins with a combination of bumping bass and minimal, yet potent sampling from Gensu Dean. Planet Asia matches the tone of each track and meshes in nicely with his scattered rhyme schemes. On "Thoroughest" and "Cochise," the combination creates a sound some might find similar to MF DOOM. But the sound switches as the album moves along. With Tristate alongside for a guest verse on "Dignity," both artists hone in as Gensu Dean returns to a more digestible breakbeat sound, while Planet Asia boldly address his peers, declaring, "Shit that I be kickin' is kind of different / Ya niggas is bleach brainwash undercover molly-sniffers / Fuck the politickin' / My only mission is to bomb the system…" His distaste for the most vastly consumed brand of Hip Hop is a common theme throughout Abrasions, but the blunt lyricism here especially hits home for fans of the underground.
While both artists consistently provide solid efforts on each track, the cohesiveness of their bond is, at times, slightly less steady. On "Aura," Gensu Dean steals the show with a captivating beat that dominates the verses. Likewise on "Do What I Want," Planet Asia's quotable lyrics and a soulful hook provided by the Larina & Washey Choir lack the impact they deserve, over a less exciting beat. Instances like these, however, are few and far between. The duo makes up for any stumbles along the way, with tracks like "Faces On The Dollar" and "Tough" that provide the street lyrics and bumping production both artists are known for. And a real treat comes at the end on "Thyself" which features David Banner and Tragedy Khadafi over what could be one of the album's best beats.
As a whole, the pair succeeds in establishing a commendable creative chemistry. Planet Asia's gritty lyrics and Gensu Dean's raw production help establish Abrasions as a refreshing listen and a solid all-around effort for both artists that is true to form.


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Inkscape joins the Open Invention Network
2014년 3월 1일 9:12 오전
The Inkscape Board has voted in favor of the Inkscape Project joining as a member of the Open Invention Network. In so doing we pledge to never use patents aggressively against the Linux System.
As part of the OIN, we join almost 750 projects and companies from the software industry in a pledge that covers over 2,100 Open Source packages. This helps to reduce risk on the core Linux System and other middleware technologies.
Valer Mischenko of OIN sums it up: "This is the largest community to address software patent challenges in the world. The idea is: when everybody pledges freedom, there will be no wars."
For more information, please read on, or go to openinventionnetwork.com


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Safety, Antiviral Activity, and Pharmacokinetics of GSK2336805 With Peginterferon and Ribavirin in Chronic Hepatitis C Subjects
This study has been completed.
Information provided by (Responsible Party):
ClinicalTrials.gov Identifier:
First received: July 7, 2011
Last updated: November 15, 2012
Last verified: June 2012
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Detailed Description:
GSK2336805 is a hepatitis C virus (HCV) NS5A inhibitor being developed for the treatment of chronic hepatitis C (CHC). This study will assess the safety, antiviral activity, and pharmacokinetics of GSK2336805 alone and in combination with peginterferon alfa 2a and ribavirin in subjects with chronic hepatitis C (CHC).
|Hepatitis C, Chronic
|Drug: GSK2336805 Drug: Pegylated interferon alfa-2a Drug: Ribavirin Drug: GSK2336805 Matching Placebo
|Phase 2
|Study Type:
|Study Design:
|Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Participant, Investigator)
Primary Purpose: Treatment
|Official Title:
|Double-Blind, Randomized, Placebo-Controlled Study to Assess Safety, Efficacy, and Pharmacokinetics (PK) of GSK2336805 in Combination With Peginterferon and Ribavirin in Treatment-naive Chronic Hepatitis C Subjects With Hepatitis C Virus Genotypes 1 or 4
Resource links provided by NLM:
MedlinePlus related topics: Hepatitis Hepatitis A Hepatitis C
Drug Information available for: RibavirinU.S. FDA Resources
Further study details as provided by GlaxoSmithKline:
Primary Outcome Measures:
- Safety/tolerability of GSK2336805 in comparison with placebo. [ Time Frame: 28-day treatment period ]Measured by the nature and frequency of AEs and absolute values and changes over time from predose values for hematology, clinical chemistry, urinalysis, vital signs, and ECG parameters.
- HCV viral load reduction from baseline [ Time Frame: 28-day treatment period ]HCV viral load reduction from baseline during 24 hours following a single dose of GSK2336805 in comparison with placebo and proportion of subjects achieving rapid virological response, defined as the proportion of subjects below the assay lower limit of detection after 4 weeks of treatment (Day 28) in comparison with placebo.
Secondary Outcome Measures:
- Composite of pharmacokinetics, Day 1 [ Time Frame: Pre-dose, 1, 2, 4, 6, 8, 24 hours post-dose ]Area under the concentration-time curve (AUC), maximum plasma concentration (Cmax), Time of maximal plasma concentration (Tmax)
- Composite of pharmacokinetics, Days 7, 14, 21 [ Time Frame: Post-dose ]Area under the concentration-time curve (AUC), maximum plasma concentration (Cmax), Time of maximal plasma concentration (Tmax)
- Composite of pharmacokinetics, Day 28 [ Time Frame: Pre-dose, 2-4 hours post-dose ]Area under the concentration-time curve (AUC), maximum plasma concentration (Cmax), Time of maximal plasma concentration (Tmax)
|Study Start Date:
|July 2011
|Study Completion Date:
|December 2011
|Primary Completion Date:
|December 2011 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: GSK2336805
Study Part 1
Drug: GSK2336805
Active Investigational Drug
Placebo Comparator: Placebo
Study Part 1
Drug: GSK2336805 Matching Placebo
Placebo of Investigational Drug
Other Name: Placebo
Experimental: GSK2336805 + pegylated interferon alfa-2a + ribavrin
Study Part 2
Drug: GSK2336805
Active Investigational DrugDrug: Pegylated interferon alfa-2a
Standard of Care drug
Other Name: PegasysDrug: Ribavirin
Standard of Care drug
Active Comparator: Placebo + pegylated interferon alfa-2a + ribavirin
Study Part 2
Drug: Pegylated interferon alfa-2a
Standard of Care drug
Other Name: PegasysDrug: Ribavirin
Standard of Care drugDrug: GSK2336805 Matching Placebo
Placebo of Investigational Drug
Other Name: Placebo
Detailed Description:
HCV infection is a major public health problem globally and a leading cause of chronic liver disease. New medications are needed that are better tolerated and offer a greater chance of achieving sustained viral clearance compared to currently available therapy. GSK2336805 is a HCV NS5A inhibitor being developed for the treatment of subjects with CHC. This Phase II, double blind, randomized, placebo-controlled study will assess the safety, antiviral activity, and pharmacokinetics of GSK2336805 alone and in combination with peginterferon alfa 2a and ribavirin in subjects with CHC. Subjects will be randomly allocated on a 2:1 basis to GSK2336805 or matching placebo and will be stratified by IL28B status and HCV viral genotype (genotype 1 or 4). The study consists of 2 parts. In Part 1, GSK2336805 or matching placebo will be given as single-dose monotherapy (Day 1). In Part 2, GSK2336805 or matching placebo will be co-administered with peginterferon alfa-2a and ribavirin through 4 weeks of treatment (Days 2 to 28). After completion of Part 2, GSK2336805/matching placebo will be discontinued and subjects will be offered continued standard-of-care anti-HCV therapy.
|Ages Eligible for Study:
|18 Years to 70 Years (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Key Inclusion Criteria:
- Documented chronic genotype 1 or genotype 4 HCV infection
- Naïve to all HCV antiviral treatment(s)
- Agree to IL28B genotyping
- A body mass index >18 kg/m2 but not exceeding 36 kg/m2
- Liver biopsy obtained within 3 years (36 calendar months) prior to the Day 1 visit, with a fibrosis classification of non-cirrhotic. If no recent (<36 months) liver biopsy is available, a study qualifying biopsy must be performed prior to Baseline (Day 1)
- All fertile males and females must use two forms of effective contraception between them during treatment and during the 24 weeks after treatment ends
- Otherwise healthy as determined by the medical history, physical examination, ECG findings, and clinical laboratory measurements performed at Screening
Key Exclusion Criteria:
- Positive test at Screening for hepatitis B surface antigen (HBsAg) or anti-human immunodeficiency virus antibody
- History of any other clinically significant chronic liver disease
- History of ascites, variceal hemorrhage, hepatic encephalopathy, or conditions consistent with decompensated liver disease
- Positive results on urine screen for drugs of abuse test at Screening (unless used as medical treatment, e.g., with a prescription)
- History of alcohol/drug abuse or dependence within 6 months of the study start (unless participating in a controlled rehabilitation program)
- Screening ECG corrected QT interval value greater than 450 ms and/or clinically significant ECG findings
- A personal or family history of Torsade de Pointes findings
- Pregnant or nursing women
- Males with a female partner who is pregnant
- Abnormal hematological and biochemical parameters as specified in the protocol
- History of major organ transplantation with an existing functional graft
- Thyroid dysfunction not adequately controlled
- Subjects with a history of suicide attempt or hospitalization for depression in the past 5 years and/or any current (within 6 months) severe or poorly controlled psychiatric disorder
- History or current evidence of immunologic disorder; pulmonary, cardiac, or pulmonary disease; seizure disorder; cancer or history of malignancy that in the opinion of the investigator makes the subject unsuitable for the study
- Participation in a clinical study with an investigational drug, biologic, or device within 3 months prior to first dose administration
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01439373
Please refer to this study by its ClinicalTrials.gov identifier: NCT01439373
|United States, California
|GSK Investigational Site
|Anaheim, California, United States, 92801
|GSK Investigational Site
|Chula Vista, California, United States, 91911
|GSK Investigational Site
|Coronado, California, United States, 92118
|GSK Investigational Site
|La Mesa, California, United States, 91942
|GSK Investigational Site
|Oceanside, California, United States, 92056
|United States, Florida
|GSK Investigational Site
|Miramar, Florida, United States, 33025
|United States, Nevada
|GSK Investigational Site
|Las Vegas, Nevada, United States, 89109
|United States, Oklahoma
|GSK Investigational Site
|Tulsa, Oklahoma, United States, 74104
|United States, Texas
|GSK Investigational Site
|Houston, Texas, United States, 77004
|Puerto Rico
|GSK Investigational Site
|San Juan, Puerto Rico, 00927
Sponsors and Collaborators
|Study Director:
|GSK Clinical Trials
More Information
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Keywords provided by GlaxoSmithKline:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on September 21, 2017
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Gardner S, Cutrell A, Elko-Simms C, Adkison K, Hamatake R, Walker J, Rodriguez-Torres M, Hong Z. A double-blind, randomized, placebo-controlled study to assess the safety, antiviral activity and pharmacokinetics of GSK2336805 when given as monotherapy and in combination with peginterferon alfa-2a and ribavirin in hepatitis C virus genotype 1-infected treatment-naive subjects. Liver Int. 2014 Jul;34(6):e89-95. doi: 10.1111/liv.12334. Epub 2013 Oct 16.
|Responsible Party:
|ClinicalTrials.gov Identifier:
|NCT01439373 History of Changes
|Other Study ID Numbers:
|Study First Received:
|July 7, 2011
|Last Updated:
|November 15, 2012
Keywords provided by GlaxoSmithKline:
chronic hepatitis C
NS5A inhibitor
pegylated interferon
Additional relevant MeSH terms:
Hepatitis C, Chronic
Hepatitis A
Hepatitis C
Hepatitis, Chronic
Liver Diseases
Digestive System Diseases
Hepatitis, Viral, Human
Virus Diseases
Enterovirus Infections
Picornaviridae Infections
RNA Virus Infections
Flaviviridae Infections
Peginterferon alfa-2a
Antineoplastic Agents
Antiviral Agents
Anti-Infective Agents
Molecular Mechanisms of Pharmacological Action
Immunologic Factors
Physiological Effects of Drugs
ClinicalTrials.gov processed this record on September 21, 2017