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Halloween Continues With Universal Monsters And Walking Dead...
Horror and monsters fans don't have to be sad because it's November; check out the cool items on sale this week from Diamond Select Toys and get your horror fix!
Universal Monsters Vinyl Bust Banks: Creature from the Black Lagoon and Frankenstein
An all new series of 8 inch bust banks capturing Universal Monsters! Beginning with Frankenstein sculpted by Gabriel Marquez and the Creature sculpted by Bill Mancuso.
Walking Dead Zombie Vinyl Bust Bank
Brand new 8 inch vinyl bust bank capturing the zombie look from the comic book, including the series' logo. Sculpted by Eli Livingston.
Universal Monsters Black-and-White Legacy Series 2 Box Set
Three of the most famous Universal Monsters Dracula, Frankenstein and the Bride of Frankenstein in their original-black and-white appearances! These exclusive 7-inch scale figures will only be available as part of this set, and come in a display-quality window box. Designed and sculpted by Rudy Garcia, Gabriel Marquez and Jean St. Jean.
Source: Art Asylum Blog
To insure your action figure collection, get in touch with Collectibles Insurance, the official insurance company of the Figures.com network. Say "Figures.com" to get 5% off your first term premiums.
To buy action figures, take a look at BigBadToyStore.com, Toynk.com, PastGenerationToys.com, BriansToys.com, ToyWiz.com, and MonkeyDepot.com.
For action figures, statues and sculptures, go to CSMooreStudio.com.


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Hearing set in suit over missing IU student
A federal judge has set a December hearing on a motion to dismiss a lawsuit filed by a missing Indiana University student's parents against three men who were with her the night of her disappearance.
Lawyers for the parents of Lauren Spierer and the three men are to appear before Judge Tanya Walton Pratt on Dec. 2 at the federal courthouse in Indianapolis.
The lawsuit claims the fellow IU students gave Spierer alcohol, then failed to make sure the 20-year-old Greenburgh, N.Y., native made it back to her Bloomington apartment safely after a night of partying in June 2011.
Lawyers for Corey Rossman, Michael Beth and Jason Rosenbaum maintain the Spierers have no evidence their daughter is dead and that they weren't responsible for the safety of an adult.
(Copyright 2013 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.)

subset: commoncrawl


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Family tree▼
Facts and Events
Jerry Davis: Biographical Information
Susan Bennett was the daughter of Adam Bennett, who was once enslaved at Magnolia Plantation on the Ashley River, St. Andrews, Charleston, South Carolina. Descendant family oral history states that Susan's first husband was Lingard Davis, and that they had one son named Jerry.
We would like to learn more about Lingard Davis and Jerry Davis. If you have information and/or documents to share, please contact us! We will gratefully acknowledge your contribution.
Family Group Sheet
More Features
You can click on "More" then "Pedi-Map" at the top right corner of this page to view pedigree charts, maps, timelines, thumbnail images and more for Jerry.
About This Page
This page is part of a groundbreaking research project to rediscover the family lineages of enslaved people on Drayton family plantations in Barbados and the United States. To read more about this historic research, please visit the article below:
Genealogy of Enslaved Communities on Drayton Family Plantations: A Research Project Sponsored by the Magnolia Plantation Foundation of Charleston, SC


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The publication of Jim Carroll's diary, entitled The Basketball Diaries: Age Twelve to Fifteen (1978), had been eagerly awaited. The book, which is generally referred to by its main title alone, had started appearing in excerpt form throughout the late 1960s and early 1970s in various literary publications. Carroll claimed that the diaries were written at the time in which the events related took place. However, some critics wondered how much the diaries were edited before publication, especially since the book includes many outrageous incidents. Regardless of its authenticity, the book made a statement when it was published. Some people at that time were glorifying the image of life in the 1960s urban counterculture. Carroll's gritty diary was explicit; it took readers inside the real world of drug addiction, male prostitution, and crime in 1960s New York.
The book also discussed what life was like for war babies—people who grew up under the constant fear of nuclear annihilation during the Cold War—and the difficulty in remaining neutral in the 1960s antiwar debate. The Basketball Diaries has become Carroll's best-known work, especially after the release of a 1995 film adaptation starring Leonardo DiCaprio. In 1987, Carroll published a sequel, Forced Entries: The Downtown Diaries, 1971–73.


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Install from zip. Follow all other steps to get makemkv etc...
I am updating this first post as a placeholder for the current state of development of the plugin. The original script I've now abandoned as a development platform, I'll keep the script location up for a while though until we know that the plugin is fully functional.
Ok, now for the new: I've released a version of the BluRay video plugin. Please be aware that this is still somewhat a development version. I've tested as well as I could on vista and did play a disc on Linux so I'm reasonably comfortable that it will work. However, until you've tested for your self I would urge you to keep a copy of the original script around so you can switch back to that.
If you have any feedback, suggestions or bugreports please use this thread so we can all share, thanks!
* A working install of MakeMKV. If you're installing under Linux, make sure you install both the source and the binary package, otherwise the commandline tool won't be there.
* A BluRay source, either a disc or iso's or something.. (What's the point otherwise...)
Install the plugin
* Download the current version of the plugin here
* Unzip/Install the plugin in your plugin/video path to make it act as a video plugin
Use the plugin
Browse to your video plugins and if all went well with the installation a BluRay plugin should now be selectable. Enter it and play some BluRay's.. Initially there are 3 sources options and a selection to go to the plugin settings. Source options are:
* Disc, play a disc insterted into your BluRay drive (can also be a DVD if you really want to..)
* Filelocation, browse for a filelocation in your video sources and use it as a BluRay source. Selections can be either and ISO image or an index.bdmv file if the dir has been extracted. Note: Since the actual streaming of the image is delegated to the makemkvcon executable only files accessible at the filesystem level can be used. If you've used an XBMC selected samba source, iso files from this location won't work.
* Remote, you can let it connect to a remote machine with the stream setup already.
All three source options have both a 'play' and 'browse' selection. If you choose 'play' the plugin will automatically determine the longest running feature on the disc and start playback of that. Handy if the bluray has only one main feature (ie movies). If you choose 'browse' the plugin will display a selection of chapters on the disc and let's you select the one you want to play. Handy if you're looking at a series BluRay with multiple episode.
Unfortunately there is not a lot of information available on the streams when selection browse. This is because the MakeMKV streamer doesn't supply any more info unfortunately.
Explanation of the settings:
Settings are divided into three sections
* General Settings
o MakeMKV location. -> Point to your makemkvcon executable. If it is on your path the default should be fine, otherwise just browse to the correct location and select it.
o Seconds to wait for stream -> Tell the script how long it should wait for makemkv to finish parsing the disc/iso before calling it quits and exiting. Default is 2 minutes.
o Local portnumber -> If running makemkvcon locally this is the portnumber that the script will listen to. Default should be fine
* Browseable Options
o Enable disc support -> Turn on or off disc support
o Enable File location support -> Turn on or off support for browsing to ISOs and directory structures for playback
o Enable Remote location support -> Turn on or off support for streaming from a remote location
* Remote Setup
This section will only show up if you've enabled remote location support. Enter the ip address and portnumber of the remote makemkv stream location.
* Fixed code issue with exception handling causing real error to be 'forgotten'
* Fixed issue with logging code which preventen discs from streaming (oops, already!)
* Initial release of the plugin, based on the script code that has gone before
* Main feature selection now more 'intelligent' by selecting longest stream
* Changed settings around to make more sense by allowing source categories
===== OLD Script:
Location to get the old script: http://www.bultsblog.com/BluRay-script.zip
==== OLD first post starts here
Just a heads up that I've succeeded in playing back an original Blu Ray disk in the blu ray drive using XBMC. It's not as user friendly as is could be yet, but at least it's now possible.
- Install MakeMKV
- Insert Blu ray
- makemkvcon stream disc:0
- Get a browser somewhere and point it to:
- Watch the movie....
You can browse the Blu Ray index by pointing to http://192.168.0.103:51000/ By the way.
Now to figure out how to pour this into a plugin somehow...
I apologise if this was already widely known, but it was new to me.


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Incoming Federation CEO Naomi Adler will have her work cut out for her when it comes to setting critical goals and inspiring the local community to give.
This week's announcement of a new CEO to lead our Jewish Federation couldn't have been more timely. It comes just days before Super Sunday, when hundreds of volunteers will converge at Barrack Hebrew Academy to raise funds for the many important causes Federation supports.
The naming of Naomi Adler, an attorney-turned-fundraising executive who has a stellar reputation for leading two United Way operations in New York state, has generated excitement and anticipation.
When she arrives to take the reins in May, she will have her work cut out for her.
The top professional plays a crucial role in setting the tone and building the relationships that will determine how Federation is perceived in the community by donors, grant recipients, Jewish organizations, synagogues and other stakeholders.
But the CEO does not act in a vacuum; she must work in concert with professional staff and lay leaders who together craft a common agenda and set critical goals and priorities.
Ours is a diverse, vibrant community filled with intellectual fervor, spiritual creativity and philanthropic generosity. What's often missing is a sense of cohesion, an understanding that across the economic, political and religious divides, we share a common purpose and destiny.
While we may quibble over how and where certain funds are distributed, there can be no argument about the collective good that comes from the multitude of programs our organized community supports.
Federation dollars support three main priority areas: caring for those in need, from seniors to the Jewish poor; enriching Jewish life through educational and identity-building programs; and supporting people in Israel and in the former Soviet Union.
Supporting the Federation, as Adler put it, "is the most impactful way to support the largest number of people. There's no better way to get a bang for your buck philanthropically."
Sadly, that ethos of collective responsibility has dissipated in recent years. It used to be that if you were Jewish, you gave to Federation. It was as automatic as celebrating Passover or going to synagogue on Rosh Hashanah.
We have an opportunity to reinvigorate our community with new leadership and a new spirit of giving.
Naomi Adler will be arriving officially in May. But we can start — and keep — giving generously now. Answer the call when your phone rings on Sunday. It's a super time to give.


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It Comes at Night
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VHS Massacre Cult Films and the Decline of Physical Media
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Document Actions
The Ombuds Officer
The Charter for a Governance of Hunter College established the office of the Ombuds Officer, who serves as an independent agent to improve communication between individuals and the College. The Ombuds Officer receives complaints and may undertake independent investigation if the usual procedures have proven inadequate or have been exhausted, and may recommend action to any officer, committee, or organization of the College.
The Ombuds Officer serves as an independent agent to improve communication between the individual and the institution. This includes receiving complaints, investigating, and taking appropriate action-such as counseling, negotiating, and persuading. The Ombudsman provides avenues through which institutional injustices can be rectified and the causes of these injustices alleviated. Complaints can be made with anonymity assured.


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Here's how to maximize control-loop performance
Tune your processes to stop giving away valuable commodities
Motor gasoline is blended at the refinery to specifications that include octane rating, typically grades of 87 and 93 octane; at the pump these may be further blended to produce an intermediate grade such as 89 octane. An engineer I met was especially proud of how well octane number was controlled at his refinery—but he always filled his car at a competitor's station, although the price per gallon was the same. His rationale was that the competitor's control over octane number was more variable, but still had to meet the minimum standard of 87 for regular grade—hence its average octane rating was higher by that variability. The competitor's refinery was giving away octane, and he was willing to accept it. The analysis below can be used to describe the cost of giving away any valuable ingredient, or any operating cost associated with the variability of control.
Safe-Side Variations
The cost to the refinery in excess octane giveaway is a direct function of its variability, with two possibilities shown in the step-load response curves of Fig. 1. The upset could either drive the controlled variable in the "safe"direction shown in the black curve, or the "unsafe"direction, shown in red. Here, "safe"is meant to infer that the controlled variable is driven toward the favorable side of the specification limit, in this case above the 87-octane specification. Safe-side variations do not require any action either by the operator or any automatic response, because product specifications are not thereby violated. (Although there is a slight overshoot of setpoint on the return trajectory and therefore a momentary violation, any downstream capacity at all would absorb this brief transient, and it would not appear in the final product.) Safe-side variations simply result in an economic loss that is quantifiable.
If the setpoint in Fig. 1 is also the specification limit, and the measured octane rating rises due to the upset before returning to setpoint, the octane giveaway is related to the integrated error of the controlled variable from setpoint. Integrating this deviation or error e between controlled octane and its setpoint over time t gives the Integrated Error IE in terms of octane-minutes. Subsequent multiplication by the current product flow rate in gal/min yields octane-gal given away during that interval. Multiplying that result by the cost difference in the dollars/gallons/octane number converts the integrated error into dollars lost.
The cost function may not be linear. For example, the price difference at the pump between 87 and 89 octane, and between 89 and 93 octane may both be $0.10 per gallon, which probably reflects market forces rather than production cost. Nevertheless, small variations in the function around a given specification can be assumed to be linear, allowing IE to be a useful criterion in evaluating the cost of poor control.
When using PI or PID control over any variable, integrated error is directly related to the size of the disturbance and the controller settings. The ideal PID controller is simply represented in Eq. (1):
where m is the variable manipulated by the controller, and P, I and D are its proportional band in percent and integral and derivative time settings respectively. This formula may be evaluated both before and after an upset, when the deviation e and its time derivative are both zero. If the controller output has changed between those two steady states, there will be an integrated error:
Equation (3) applies equally to interacting and non-interacting PID controllers and PI controllers as well. There are some obvious conclusions to be drawn from it: To minimize the cost associated with IE, minimize the feedback control effort Δm required to respond to an upset (by using feedforward), and reduce the P and I settings (without sacrificing stability).
Unsafe-Side Variations
When the controlled variable wanders to the unsafe side of the specification limit, decisions have to be made. In failing to meet requirements upon which the product is to be sold, it must be set aside for blending with better-than-acceptable product, rejected to a less-valuable use or rerun. All of these operations are costly and cause disruptions affecting production rate. Operators avoid them if at all possible.
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Our general interest e-newsletter keeps you up to date on a wide variety of health topics.
Learn what causes cancer pain and how you can work with your doctor to ensure your cancer pain is controlled.
Timothy Moynihan, M.D.
Not everyone with cancer experiences cancer pain, but 1 out of 3 people undergoing cancer treatment does. If you have advanced cancer — cancer that has spread or recurred — your chance of experiencing cancer pain is even higher.
Cancer pain occurs in many ways. Your pain may be dull, achy or sharp. It could be constant, intermittent, mild, moderate or severe.
Timothy J. Moynihan, M.D., a cancer specialist at Mayo Clinic in Rochester, Minnesota, offers some insight into cancer pain, reasons why people might not get the pain treatment they need and what they can do about it.
Cancer pain can result from the cancer itself. Cancer can cause pain by growing into or destroying tissue near the cancer. Cancer pain can come from the primary cancer itself — where the cancer started — or from other areas in the body where the cancer has spread (metastases). As a tumor grows, it may put pressure on nerves, bones or organs, causing pain.
Cancer pain may not just be from the physical effect of the cancer on a region of the body, but also due to chemicals that the cancer may release in the region of the tumor. Treatment of the cancer can help the pain in these situations.
Cancer treatments — such as chemotherapy, radiation and surgery — are another potential source of cancer pain. Surgery can be painful, and it may take time to recover. Radiation may leave behind a burning sensation or painful scars. And chemotherapy can cause many potentially painful side effects, including mouth sores, diarrhea and nerve damage.
There are many different ways to treat cancer pain. One way is to remove the source of the pain, for example, through surgery, chemotherapy, radiation or some other form of treatment. If that can't be done, pain medications can usually control the pain. These medications include:
These drugs can often be taken orally, so they're easy to use. Medications may come in tablet form, or they may be made to dissolve quickly in your mouth. However, if you're unable to take medications orally, they may also be taken intravenously, rectally or through the skin using a patch.
Specialized treatment, such as nerve blocks, also may be used. Nerve blocks are a local anesthetic that is injected around or into a nerve, which prevents pain messages traveling along that nerve pathway from reaching the brain.
Other therapies such as acupuncture, acupressure, massage, physical therapy, relaxation, meditation and humor may help.
Unfortunately cancer pain is often undertreated. Many factors may contribute to that, some of which include:
Reluctance of doctors to ask about pain or offer treatments. Some doctors and other health care professionals may not specifically ask about pain, which should be a normal part of every visit with your doctor.
People with cancer should be asked if they are having any pain. If they are, the doctor should stop there and deal with the issue.
Some doctors don't know enough about proper pain treatment. If this is the case, your doctor might refer you to a pain specialist.
Other doctors may be concerned about prescribing pain medications because these drugs can be abused. However, people in pain are very unlikely to abuse pain medications.
Reluctance of patients to speak up about pain. A second factor might be a person's own reluctance. Some people might not want to "bother" their doctors with the information, or they may fear that the pain means that their cancer is getting worse.
Some are reluctant to report it or report it as thoroughly as they should because they're worried about what doctors or others might think of them if they complain. They might feel that because they have cancer, they're supposed to have pain and be able to deal with it. That simply isn't true.
Fear of addiction. Another factor might be a person's fear of becoming addicted to pain medications. This is something that we know doesn't typically happen if you take medications for pain.
If you take medications when you're not in pain or to get high, then, yes, you can get addicted. But the risk of addiction for people who take pain medications in an appropriate fashion — for pain — is very low, so this shouldn't be a concern.
Fear of side effects. Some people fear the side effects of pain medications. Many are afraid of being sleepy, being unable to communicate with family and friends, acting strangely, or being seen as dependent on medications. People are also sometimes afraid that taking morphine may shorten their life. There is no evidence of any of these happening if the medication is dosed appropriately.
Recent evidence suggests that good control of symptoms, including pain, actually helps people to live longer.
And although strong pain medications can cause drowsiness when you first take them, that side effect usually goes away with steady dosing.
Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission.
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Trinity Episcopal Church celebrating 100 years in western Grand County
June 5, 2012
Trinity Episcopal Church marks 100 years of Episcopal presence in western Grand County on Sunday, June 10. The Right Reverend Robert O'Neill, Bishop of Colorado, will preach and celebrate Holy Eucharist at 11 a.m. at the church located at 9th and Central in Kremmling. Members of the congregation will provide a picnic lunch following the service. Everyone is invited to attend and help Trinity celebrate this historic event.


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Topic: my beloved mum.
my adorable mum. aged- 52 passed away 26/04/2007. 10.10 pm my mum was diagnosed with cc just a mear 8 wks ago. her life revolved around her children and grand children. she was a very popular lady who had time of day 4 every one and anyone. she was loving and caring who lived life as normal as she cud as from the early yrs 30s she was riddle with authuritis but she was very independant, never complained she just got on with it. always had a smile rite up to the time of my mum passing. words cant describe how im feeling, mixed emotions numb, hurt, and empty. my mum was my world.the only the thing i hate myself for is not being there wen the lord took her. but that was probably the way she wanted it. she saw all her family before she left for a better place. we all spent all day with her just didnt get back there in time wen she was ready but then again mum ad always been arkward. she was a remarkable young lady, she did av a short battle but sed she wasnt going to be beaten, in the end she had 2 bugs one was two b the most defiant of the two and wouldnt give in. she ad fought all day to stay and u could see her in her eyes she was weak and she was telling us she couldnt fight it no more. i will always remember her as the happy loving mum as she was. R.I.P mum love u always.


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The Trinity
Black Ninja!
Black Ninja!
Senior Member
Black Ninja!
Black Ninja!
Black Ninja!
You know I didn't know what to title this blog. I had a few come to mind. Originally, "A Story about Storytelling". Then "The Good, the Bad, and the Just Plain Ugly". But I've decided on a title as mixed up as SD! was this week. Which is partly what's given me the urge to blog all over everything again. And I just gotta. Had to.
But first, something that's irked
You know I'm gonna fire off a quick rant because I'm sick of seeing this. Chris Jericho and Austin and others talking about people stealing their stuff.
Originally Posted by Everything is Jericho
Y'know I've had a tirade about commentary kicking around my head for a while. Well, here it is.
Imagine a sports commentator. Imagine him in your mind, hearing him speak. Chances are you're imagining someone with a unique voice narrating the action. You're imagining that because that in essence is what sports commentating is. It's a narration of what's going on by a guy who sounds good.
John Cena has sucked for a long time.
It's common knowledge that the only people still in Cenation are kids and women. Even the few guys who still rock fruity have one foot out the door and dreams of greener pastures in Chicagoland. You take a look at the biggest guys in WWE, the "go-home" guys, and that's John Cena and Randy Orton. And the difference there can be summed up
Decent ppv last night. I judge a ppv mainly on how well I remember it. And I remember practically everything regarding the matches of CM Punk vs. Rey Mysterio, Christian vs. Randy Orton, and R-Truth vs. John Cena.
CM Punk vs. Rey Mysterio. Now this is the CM Punk we expect. He and Rey put on the best match of the night with some unbelievable sequences. They had some pretty heavy competition


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NEW YORK — Walgreens is in the process of introducing a wide-scale national campaign that has its pharmacists recommending Walgreens store-brand products in favor of national brands, the New York Times reported Thursday.
The new ad campaign, an extension of Walgreens' "There's a Way" campaign introduced last year, will mark the first time the company is promoting its private-label offerings beyond the Sunday circulars and in-store point-of-purchase material.
The reason behind the change in tactics is simple — store brand is in vogue. Out of more than 1,000 adults surveyed in January, 84% purchased a store-brand over-the-counter medicine, and 36% noted that they had increased their amount of private-label purchases in the past year, according to a survey conducted by Opinion Research on behalf of Walgreens, the Times reported.
Walgreens will be featuring the campaign as part of its partnership with ParentsAsk.com, which first was implemented last spring. ParentsAsk.com features a Walgreens-branded site with advice videos from Walgreens pharmacist Stacia Woodcock. Woodcock also will be recommending Walgreens' store-brand products. Check out the videos here.
According to the Times report, Walgreens will place banner ads comparing Walgreens' store brands with name brands on such websites as ABC.com and CBS.com. Walgreens also will partner with the women-centric blog publishing network BlogHer.


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HEBRON ESTATES - Over the past two seasons, the North Bullitt boys' soccer program has put an entertaining style of play on the field.
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Yes, old man Freedman's 95th birthday at the Vacaville city library went well. Thanks for asking. During down time, Pops says to me, "The only problem with this library is they have five copies of a biography about Marilyn Monroe and none of James Monroe."
One of my younger relatives wanted to know if James was Marilyn's husband.
Uh, no, I said, but both have a connection to the presidency. So much for that parochial school education.
STUPOR MAN ... In Scranton, Pa., a drunk 24-year-old man wandered into the wrong house, cooked himself a steak and chowed on some seafood from the fridge. Sounds like college memories. Anyway, the "suspect" apparently eluded the sobriety check point at the front door. He's like TV's most interesting man in the world: He doesn't drink beer often, but when he does, he drinks Doce Equis.
SEAL OF APPROVAL ... The "Save the Manatee Club" is promoting a holiday message "Peace for All." As an endangered species, every time a calf is born, someone yells, "Oh, the new Manatee!" Nothing like a zeppelin reference and no, not Led Zeppelin. That was a rock band. This zeppelin sank like a rock. Google Hindenburg. Or Hiddenbrooke.
AT THE COPA ... From manatee to Manilow (nice transition). Barry Manilow ("Oh, the new Mandy!), that is. The balladeer is working the HP Pavilion in San Jose on Dec. 6. Top ticket's $175 and the lowest is $10, with telescope and squinting optional. Manilow, of course, was famous for "Can't Smile Without You," which the 69-year-old has upgraded to "Can't Smile Without Denture Cream."
WITH EYES GLAZED ... At Wednesday's meeting of the Central Core Restoration Corp., V-town's business tycoon Buck Kamphausen fumed at the thought of officers possibly snagging eight hours of work in the downtown business district when the first hour and the last would be for debriefing. What's next, questioned Kamphausen, paying the cops for a donut break? Hey, maybe the coppers can hold their debriefing at a donut shop! Best plan to fritter away a shift.
BARACK IS BACK ... V-town's Brenda McNeill, a delegate to the Democratic convention, is still flying after the election. "I'm tired, relieved, but very satisfied," she said. Sounds like me after a big meal.
GRAVY TERRAIN ... Thanksgiving at the Good Samaritan Missionary Baptist Church in Vallejo should be interesting. Volunteers include members of the Jesse Bethel High School football team and the Kings of Cali motorcycle club. Sure don't want to be a wishbone pulled in each direction by both those groups.
CRIME PAYS BIG ... Former Giant Miguel Cabrera gets suspended 50 games for performing enhancing drugs. Not only does he get a full World Series share for not playing in the World Series -- roughly 200 grand -- he signs a two year, $16 million contract with Toronto. That's like extending unemployment benefits to Bernie Madoff. OK, not quite. Still, some message to send to kids. Caught cheating on math test? You've earned a scholarship to Stanford!


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Posted 5 years ago
(2 items)
Here we have a german Heer used folding knife that a medic used. it is a un-issued item(meaning it was from his personal wear).
I like how he cut it down for what he used it for, most likly for cutting away the wool uniform to get at the wound.
i picked this up 2 years ago from a friend i knew from re-enacting, he owed me money that he didnt have at the time and offered this.


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Third candidate lines up for sheriff
February 27, 2014
The race for Douglas County sheriff has attracted a third candidate.
Michael Gyll, 43, a Johnson Lane resident, said Thursday he would file Monday for the nonpartisan office.
He recently retired after a 21-year career with the Nevada Highway Patrol and Department of Public Safety Investigations Division.
Sheriff Ron Pierini, 61, announced last May he would seek re-election to his fifth term. Minden financial planner and DCSO reserve deputy David Brady, 58, also announced his candidacy. Brady is a former school board member and county commissioner.
It's been more than 30 years since there has been a contested race for sheriff. With three candidates, the contest will go to a June 10 primary with the top two facing off in the November election.
Gyll said he had been approached by several people who wanted to see a "fresh face" in the DCSO.
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He retired from the Department of Public Safety in June, and has spent several months thinking about the campaign.
With his law enforcement experience, and youth, Gyll said he believed he could make a difference.
"I believe we need to shine the star, it's a little tarnished. I think we need a change of the old guard and more transparency," Gyll said.
"In 1988-90, Douglas County was the place to work," he said. "Young guys don't want to work there now. I think we need a house cleaning. Officers need to be proud of not only the job they do, but the place they work."
Prior to becoming a police officer, Gyll was an enlisted Army paratrooper and veteran of a foreign war.
In 1995, he was assigned to the new Minden Nevada Highway Patrol substation.
He worked his way up through the ranks at the Department of Public Safety, retiring in June 2013 as a lieutenant assigned to the investigation division as headquarters commander.
He was responsible for two narcotic task forces, a major crimes unit, polygraph examination unit, division records and retention unit, administrative assistants, budget planning and procurement officer, division fleet officer, division training and firearms coordinator.
As an administrator, Gyll said he has an open door policy.
"My people know I don't keep anything from them. I am there to give them what they need. I am about safety," he said.
He has three children, Courtney, 22; Luke, 7; and Reagyn, 5. He lives in Johnson Lane with his wife, Melissa, and their two youngest children.
"I was raised in a law enforcement family, having my father, uncles, cousins, and brother-in-law all serving with pride, commitment and courage," Gyll said.
Gyll said he was creating a website and Facebook page within the next few days.
The sheriff's race is his first attempt at public office.
"I don't think the name recognition is an uphill battle, I think it's more of a challenge," Gyll said. "We need youth at the table. There's got to be a change."


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Formula boards in waves and chop?
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Joined: 10 Feb 2012
Posts: 1120
Posted: Tue Jun 24, 2014 3:37 pm
Post subject:
Not much wind and a rough ocean, not a good combination. Formula is an all or nothing deal, planing with an appropriately sized giant sail and fin or schlogging.
That would be a pretty bad deal schlogging in a rough ocean on a Formula board and trying to get in and out thru the surf.
You are however about the size of pro Formula sailors, perhaps a bit heavier. They use their size leverage and to hold down those giant sails and strength pump them like an orangutang.
In that kind of wind you will be doing a lot of non-planing windsurfing, a narrower long board would give you the floatation you need for your size and superior glide during non-planing. Could also be used in the surf with smaller more manageable sails and not be concerned with planing, just getting in and out and playing in the waves.
I have a 8M Superfreak, it's my most used sail. Is yours an ultra light? made from kite material? They can be bagged out all the way to 499 downhaul and 212 outhaul for power in very light wind. You can also use a 460 mast if that's all you have.
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Joined: 23 Jul 2008
Posts: 577
Posted: Tue Jun 24, 2014 3:40 pm
Post subject:
bamer wrote:
But having that said: do you want to own/ sail 10-12 meter sails? Does your beach allow you to clear a 70cm fin and get a waterstart off without getting rolled by shorebreak (as bred2shred noted)?
A wide slalom setup could be an option with a board around 80-85cm wide and a ~9.5 meter rig. But realistically at 240 lbs that isn't going to get going in 8-10mph.
For the sail you could get something like a Retro which will have much more power than a race sail,
but will still be plenty fast. With this setup the fin would be closer to 50cm.
Bamer (and other's with info about this)... sorry for a slight thread hi-jack -
But, WHY would a RAF sail like a Retro (which I own and like, BTW) have more power than a race sail ???
MUCH more power, you're saying?
I don't get this at all.
From my perspective... they might be similar when well powered-up, in steady wind... sure.
But... when there are lulls (always happens)... the cambered race sail would maintain power longer and regain power sooner.
And... when exiting a jibe... a race sail would gain speed quicker.
And, if there were big gusts... a cambered sail will maintain stability better.
Anyway, that's my perspective. What am I missing? I have never thought that a sail like a Retro would have "more power" than a race sail.
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Joined: 12 Dec 1999
Posts: 18204
Posted: Tue Jun 24, 2014 4:45 pm
Post subject:
A race sail's forte is low drag, not high power. Meter for meter, they generally have less power. The first "race sail" our magazine tested in the Gorge, from Neil Pryde, came with written instructions to rig about 16% bigger than we'd normally rig. I'm sure someone will correct me if that trend has reversed since then. Flat = low drag, draft = power, generally speaking.
Last edited by isobars on Tue Jun 24, 2014 8:48 pm; edited 1 time in total
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Joined: 11 Mar 2004
Posts: 84
Posted: Tue Jun 24, 2014 5:09 pm
Post subject:
beaglebuddy wrote:
I have a 8M Superfreak, it's my most used sail. Is yours an ultra light? made from kite material? They can be bagged out all the way to 499 downhaul and 212 outhaul for power in very light wind. You can also use a 460 mast if that's all you have.
It's the ultra light version. Feels like nylon ripstop with a vinyl window. It has one small rip that the previous owner taped, but I will do a more professional repair before using it. I heard a lot of good things about the superfreak so I bought it. I'm hoping it becomes my most used sail also.
Ok, I think I'm pretty much over getting a formula board. The locals all insisted it's the only way to go. I'll stick to my big SUP + superfreak for now and see how it goes. That AHD looks sweet, a fish with a mast track, love it. That'll be on my short list when I'm ready...
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Joined: 03 Jul 2009
Posts: 3554
Posted: Tue Jun 24, 2014 5:28 pm
Post subject:
Any high volume (150+ board) used with an appropriate sized powered up sail can work just fine. Key is correct power to fly the fin, so the rest of the board glides thru the air over the chop.
Formula can work well with any long boom sail bigger than 5.7, for planing conditions.
Best call out in the ocean is a freeride board that is stronger and heavier, using a swept back BIG fin to glide over kelp beds and allow decent upwind performance.
And SUP/windsurf combo can work, but you're giving up a lot in early planing, jibing, jumping, and performance.
A longboard of 250 liters would also work, but their masttrack's aren't safe nor reliable.
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Joined: 10 Feb 2012
Posts: 1120
Posted: Tue Jun 24, 2014 5:58 pm
Post subject:
Yes the ripstop dacron with the little squares is the ultra-light version superfreak.
If the wind picks up a bit and the sail starts to tug at left and right hands becoming unstable just tighten the DH and OH a bit together towards the recommended setting otherwise for max power in low wind 499-212. Play around with it, some people may find that setting too unstable.
To make a permanent repair just use tear-aid type A tape, like this;
It will be permanent enough unless the tear is near a seam.
Cut the corners round so it won't snag and pull off, apply to both sides if you want.
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Joined: 11 Mar 2004
Posts: 84
Posted: Tue Jun 24, 2014 6:57 pm
Post subject:
The last owner used a huge patch of that "tear-aid" stuff and it looks nasty. I stopped by my favorite sailmaker and got some matching color sail repair tape. I'll tape that up on both sides and it should hold. I might even stitch it (I have access to a sailmaker's sewing machine) if I get a chance.
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Joined: 12 Dec 1999
Posts: 18204
Posted: Tue Jun 24, 2014 7:22 pm
Post subject:
zirtaeb wrote:
And SUP/windsurf combo can work, but you're giving up a lot in early planing, jibing, jumping, and performance.
Jibing? A SeaLion turns on a small dime, wind or no wind, planing or pivoting.
It planes very early considering its wave performance.
It jumps VERY well. The problem is that it and its rider then land in different places.
Define "performance". Did you watch any of the videos?
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Joined: 03 Jul 2009
Posts: 3554
Posted: Tue Jun 24, 2014 7:52 pm
Post subject:
Compare planing performance between your SeaLion and a 135 liter slalom board, please.
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Joined: 12 Dec 1999
Posts: 18204
Posted: Tue Jun 24, 2014 8:49 pm
Post subject:
zirtaeb wrote:
Compare planing performance between your SeaLion and a 135 liter slalom board, please.
I did. "It planes very early considering its wave performance.".
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Jessica Simpson is cleaning house (or rather, selling house!) in preparation for baby number two!
The Fashion Star judge has listed her "bachelor pad" for $7.995 million—and OKMagazine.com has photos of the adorable abode, courtesy of Zillow.com.
Jessica Simpson is selling her Beverly Hills bachelor pad which she bought before meeting fiance Eric Johnson
Jess stands to make a tidy profit on the home, as she purchased it for $5.275 million following her separation from then-husband Nick Lachey in 2005.
Leonardo DiCaprio, Nicole Kidman Come Out for Opening Night of Cannes Film Festival
The 5,500-square-foot home is located in a private celebrity enclave in Beverly Hills with a gated entrance and vine-covered exterior.
"Ebonized hardwood floors and fabulous crown and [base moldings] throughout are just some of the quality details in this romantically emotional home," the listing description says.
Jessica confirmed she was expecting baby number two by tweeting a photo of her baby bump at Christmas
Recently renovated, the decor is "Hamptons shabby chic" with white-washed fabrics and rich hardwoods—touches of glam are also evident throughout, with antique chandeliers in nearly every room.
Britney Spears Wants Another Child—A Daughter!
The property is situated on a third of an acre, and its park-like grounds display lush landscaping and a secluded swimming pool. An eat-in kitchen also overlooks a stone courtyard with a serene koi pond.
Jessica isn't the only famous past owner, the house has also been home to Ellen DeGeneres, Crocodile Dundee star Paul Hogan and Hollywood manager Rick Yorn.
So, what will it set you back to live like a superstar?
An estimated monthly payment for the home is $29,281, assuming 20 percent down on a 30-year mortgage.
Better start saving!
What do you think of Jessica's bachelor pad? Sound off in comments below and tweet us @OKMagazine


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Hot corner
Reggie Miller predicts Colts will destroy Bears
By Mark Montieth
January 23, 2007
Reggie Miller participated in countless pressure-packed moments during his 18 seasons with the Indiana Pacers. But he never felt as nervous then as he did watching the Colts play New England on Sunday.
"I was up and down, pacing, screaming at the TV," Miller said Monday in a radio interview with ESPN's Dan Patrick. "I couldn't believe it. It was drama at its best."
Miller, a close friend of Colts quarterback Peyton Manning, criticized New England quarterback Tom Brady for not congratulating Manning after the game.
"I'm a little miffed that when the game is over and Peyton is looking for you, that you run into the locker room," Miller said. "I'm a little miffed at that, knowing how hard this man has struggled and you've been the guy who has always knocked him down. C'mon. Show Peyton a little love."
Miller said he believes the pressure is off Manning now that the Colts have reached the Super Bowl. Naturally, he believes they will beat the Bears, too.
"All the pressure is on Sexy Rexy," Miller said, referring to Bears quarterback Rex Grossman. "I don't think they have enough offense. All the pressure is off Peyton, because his arch-nemesis, his Lex Luthor, his Kryptonite, has been Tom Brady and the New England Patriots. They have solved that. Now in South Beach, on a neutral site, in warm weather, you are not going to stop Reggie Wayne and Marvelous (Marvin) Harrison. You're not going to stop those two.
"It won't even be close. They're going to destroy Chicago. Destroy Chicago. It won't even be close."
Don't jinx us Reggie!


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i want to
The Interdisciplinary Feeding Clinic (IFC) provides outpatient evaluation for children with feeding difficulties. The patient's evaluation/plan of care formation is coordinated between disciplines at one convenient appointment for the family. Services may include assessments consisting of a variety of specialists, including pediatrics, psychology, clinical nutrition, occupational therapy and speech therapy.
Interdisciplinary Feeding Clinic
Medical Office Building at Dublin Close To Home Center
5665 Venture Drive
Dublin, Ohio 43017
Phone: (614) 355-8420
Fax: (614) 355-8410
View map and get directions
Please email completed forms to firstname.lastname@example.com.
Contact us with any questions by calling (614) 355-8420 or by logging in to your MyChart account.
Contact your Primary Care doctor to have a referral faxed (along with a copy of the child's growth chart) to (614) 355-8410. We cannot schedule an appointment without a physican referral. Once we receive the referral you will be mailed a packet of information with paperwork to complete and mail back to the clinic. After we receive the paperwork we will call to schedule the appointment.
At your initial Interdisciplinary Feeding Clinic visit you can expect to see the following disciplines:
Psychologist: The Psychologist will observe during the actual feeding assessment to assess the behaviors associated with mealtime. The Psychologist can also provide information regarding general behavior management.
Occupational Therapist/ Speech Therapist: The OT or ST will observe during the actual feeding assessment along with the Psychologist to assess the oral motor skills/positioning of the child as well as identify any problem areas regarding the mechanics of oral feedings.
Clinical Nutritionist: The dietitian will be able to provide nutritional assessments on your child by a thorough interview of the parents and analyzing the food diary/records provided by parents. For the child that is tube fed, the dietitian will be able to assess any changes that may be needed to the enteral formula, feeding schedule or formula volume. The dietitian will be able to provide guidance to help move your child to obtain/maintain adequate nutrition for age.
Physician: The physician reviews your child's case and performs an examination for medical conditions that influence the team's recommendations.
The Interdisciplinary Feeding Team was brought together to provide a comprehensive assessment of children with feeding difficulties/issues. Our team assesses the child at one appointment and conferences together throughout your appointment time to collaborate on what they find. Because of this you should expect some downtime in-between the specialists coming into your child's room during the assessment. Please feel free to bring with you toys/books etc. to help occupy/entertain you and your child during the visit. Once the team has assessed your child they will conference together to give their recommendations. A formal letter with the entire team's assessment and recommendations will be mailed to you in 2-3 weeks.
Learn more about what to expect during your IFC visit.
contact info
Nationwide Children's Dublin
Close To HomeSM Center
5665 Venture Drive
Dublin, OH 43017
Phone: (614) 355-8420
Fax: (614) 355-8410
Interdisciplinary Feeding Clinic Leadership


text:
Game Time Start: 8:30 PM ET
Where: Bradley Center, Milwaukee, WI
Officials: J. Capers, M. Ayotte, J. Tiven
Media Notes: Indiana Notes, Milwaukee Notes
Local TV: FSI
Local Radio: WIBC 93.1 FM
NBA Feeds:
REMINDER: Per PD policy, please do not share a link to, describe how to search for, request a link to, or request a PM about streaming video of a NBA game that is not coming directly through the NBA. Not even in a "wink-wink, nudge-nudge, know-what-I-mean" round-about sort of way. Thank you
Projected Starting Lineup:
Projected Starting Lineup:
Darren Collison, sore groin, day-to-day
Kwame Brown, torn talent muscle, out
|Minimally Relevant Video:
|Sitcom Wisconsin...
Semi-Relevant Video:
Eight Points, Nine Seconds
Jonathan Auping: The Pacers Are "Just Right"
Once upon a time, there was a little basketball scout named Gold E. Locks. Mr.
Locks knew basketball and he had always been able to predict which teams were
successful based on his theory that balanced basketball always gets the job done.
Well, for one weekend, Gold was assinged to scout three NBA teams: the Boston
Celtics, the Oklahoma City Thunder, and the Indiana Pacers. He decided to assess
a few areas on each team and try to figure out which team was likely to have the
most success.
Gold decided to visit each team in their home city to watch them in their
respective practice sessions. He stayed in Boston for a night and made the
personal decison that, �This city is far too busy and populated. Although the
baked beans are great, I could never live here.�
After Boston, he flew over to Oklahoma City. OKC wasn�t Mr. Locks� cup of tea
either. �This city is far too dull. I can�t believe that when I asked the hotel
concierge for night-life ideas she simply had the horse and buggy take me to the
local IHOP. No way I could live here.�
Gold next spent a weekend in Indianapolis. He felt at home. �You know, this city
is just right. Not too crowded, not too dull. I could really see myself raising a
family here.�
I�m not quite sure how Gold�s living preferences made it into this article, but
more importantly, I was able to get a copy of the notes he took from his scouting
report. Since Mr. Locks is such a great basketball mind, I thought that I might
share a few of the points he made regarding three teams that Pacers fans have
recently become familiar with.
Celtics: �This team is far too old. A few of their players seem too elderly to even
run the fast break. This is supposed to be a basketball team, not a retirement
Thunder: �This team is far too young. Young teams can make poor decisons late
in games. That James Harden guy might fool some people with his beard, but
apparently he is only 22 years old. This is supposed to be a basketball team, not
a daycare center.�
Pacers: �This team�s age is just right. Most of its core is pretty young, but the
roster has some great veterans like David West and Danny Granger. Age shoudn�t
be a problem for them.�...CONTINUE READING AT 8p9s
Owning pessimism � Why it doesn�t make you a bad person
As my Milwaukee Bucks world came crashing down around me earlier this week
I found myself, as I often do, looking to Twitter and Facebook for some sort of
kinship. I don�t know what I was looking for. I guess I wanted to see other people
complaining about the Bucks. I wanted to see people frustrated about what was
going on.
My search ended almost as quickly as it began.
I saw almost nothing.
I did see the occasional person compliment Milwaukee on its effort. Then I saw
someone in my Facebook timeline had a picture from the Knicks game with a
caption of something like, �Got last minute tickets to the Bucks game.� The first
comment was about no one ever actually making a plan to go to a Bucks game.
The second was something more simple, like the Bucks suck. I shook my head,
rolled my eyes and moved on to Twitter where some people were feeling the
same way I was.
All the national writers and bloggers I follow had little to nothing to say about
the ramifications of the Bucks-Knicks game though. A few comments about the
Knicks probably securing a playoff spot and about the Bucks having their work
cut out for them the rest of the way were made. Matt Moore had a bunch of
funny tweets throughout the night. But after the game was done on Wednesday,
the biggest regular season game the Bucks have had a couple years mind you,
pretty much no one was talking about the Bucks.
That�s our reality right now. I was incredibly charged and full of a variety of
thoughts from �I TOLD EVERYONE SO� to �Can it get any worse?� to �Maybe
Monta Ellis can work.� But only a few hundred people really cared.
No one ever really cares. The Bucks do not matter. And that�s why I am the
way I am. That�s why I write the way I write.
I�ve been thinking about this a lot lately. I want to be a more positive person. I
want to be an optimist. People at work have discussed starting a list of all the
things I hate. That�s probably a sign that I need to stop hating so many things
(or that I need to stop being so vocal about what I hate). The Bucks would
probably be on that list. Nothing in my life has ever been more love/hate than
my relationship with the Bucks.
But the hatred in me just feasts and gets stronger when I see things like this:
�It�s important for the players, the coaches, myself, the business
operation, and first and foremost for the fans,� Sen. Herb Kohl
said of reaching the playoffs. �It�s a lot easier to sell your product
when you have a winning season. If we get to the playoffs, I think
we�ll all feel that we�ve had a good season. Then we�ll hope to do
well in the playoffs.
When I see that, I just throw my hands up. The playoffs are a Band-Aid on a
shotgun wound. I feel the same way when I see the �look how hard the Bucks
are trying� stories...READ MORE AT BUCKSKETBALL


text: I saw this video on youtube about a group in Bangkok who were (and are) dealing with this same issue. From what I could tell most uses of Buddha's image and name are disrespectful. It seems from their standpoint that Buddha is meant for only the utmost respect and even using the Buddha's name is not ideal.


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2011 Quicken Loans Carrier Classic - 11-11-11
The Michigan State Spartans and the North Carolina Tar Heels tip off the first college basketball telecast of the 2011-12 seasons by facing off in the Quicken Loans Carrier Classic tonight, November 11, 2011, on ESPN. This event will take place on the flight deck of the USS Carl Vinson in San Diego, California, marking the first-ever NCAA game to be played on an active aircraft carrier. Brown United built the Bleachers and Audience Seating for this unprecedented event.
Quicken Loans and Brown United are proud to be a part of this event as a way to honor the veterans and troops who bravely serve our country on Veterans Day and every day. This event is more than two great basketball teams coming together to play in an incredible environment. Its a way to recognize and support the service of the members of the Armed Forces, the veterans and their families and all those who have made the ultimate sacrifice.


text:
Cristiano Ronaldo scored on a spectacular header for Real Madrid in a 1-1 draw with Manchester United on Wednesday night in the first leg of their final-16 Champions League series.
After Danny Welbeck opened the scoring for United in the 20th minutes with a header off a corner kick, Ronaldo rose high to meet Angel di Maria's swinging cross 10 minutes later for his 183rd goal for Madrid - and first against former his former club.
"We began very strong and suddenly they scored and the match took on another form for us," Madrid coach Jose Mourinho said.
David de Gea made several impressive saves for United, including a fingertip effort onto the post to deny Fabio Coentrao in the first half.
"Fortunately, David De Gea made some very good saves. He's been improving all season and he made an absolutely superb save there," United manager Alex Ferguson said.


text:
Investment firm RLB Holdings and Seattle-based biotech company Kineta have announced a new investment partnership focused on accelerating development of Kineta's clinical stage drug candidates. The two drug programs funded by the investment partnership are ShK-186, an immune-sparing targeted therapeutic focused on autoimmune diseases and rOAS, a pan-viral therapeutic aimed at an array of malicious viruses.
RLB Holdings and Kineta are pleased to announce a new investment partnership focused on accelerating development of Kineta's clinical stage drug candidates. The two drug programs funded by the investment partnership are ShK-186, a novel immune-sparing targeted therapeutic focused on autoimmune diseases and rOAS, a novel pan-viral therapeutic aimed at an array of malicious viruses for which there are few effective therapies.
"Ray and I personally spent a lot of time getting to know the team in Seattle and studying their business. We discovered a high caliber operation poised for growth"
"RLB Holdings found a great gem in Kineta – a company executing an innovative business strategy that also addresses the enormous global need for better and safer medicines," said Lydia Bartoszek, Managing Partner and co-founder of RLB Holdings. "Ray and I personally spent a lot of time getting to know the team in Seattle and studying their business. We discovered a high caliber operation poised for growth," added Ms. Bartoszek.
RLB Holdings is an investment firm internationally regarded for its success in selecting and managing high yield investments. RLB holds major positions in a diverse array of companies from the legendary New York Yankees to Glencore International and Horseheads Sand & Transloading Terminal in the Marcellus shale region.
"With two major investments in Kineta in a span of two months, RLB Holdings has provided us with substantial funding power to make major clinical advancements," said Charles Magness, PhD, Kineta President and CEO.
RLB Holdings' second investment, announced today, funds manufacturing of the drug lot for Kineta's forthcoming rOAS clinical trial. The drug candidate is a novel, host-directed antiviral focused on influenza, West Nile virus, Dengue fever and many other contagious pathogens. RLB Holdings made its initial investment in Kineta in November of 2012 enabling completion of first in human trials on ShK-186, Kineta's autoimmune drug program. ShK-186 targets multiple sclerosis, lupus nephritis among other chronic autoimmune diseases. ShK-186 is one of two Kineta drug programs profiled in the current issue of National Geographic magazine, (the second is focused on non-narcotic severe pain relief). Kineta has raised more than $40 million since its launch in 2008. Terms of the RLB Holdings investment were not disclosed.
RLB Holdings is an investment firm founded in 2011 by Ray and Lydia Bartoszek who co-lead the firm as managing partners. RLB has pursued a diversified strategy of investing in transformative products and services across leading edge sectors. RLB Holdings seeks to uncover valuable opportunities poised for substantial growth and also provide positive economic and community benefit. Select investments include: The New York Yankees, Glencore International, Solutionpoint International, Horseheads Sand & Transloading Terminal, Crunch Gyms, Simple Wishes and Kineta.
Kineta, Inc. is a Seattle-based privately held biotechnology company specializing in clinical advancement of high-need novel immunotherapeutic drug candidates. Our world class scientists are pioneers in developing life-changing classes of drugs. Kineta seeks to improve the lives of millions of people suffering from an array of diseases. Kineta's progressive business model focuses on targeting unmet medical needs and rapid achievement of important clinical milestones.
This document contains certain forward-looking statements, including without limitation statements regarding Kineta's plans for drug manufacturing and clinical studies. You are cautioned that such forward-looking statements are not guarantees of future performance and involve risks and uncertainties inherent in Kineta's business which could significantly affect expected results, including without limitation progress of drug development, drug manufacturing, clinical testing and regulatory approval, developments in raw material and personnel costs, and legislative, fiscal, and other regulatory measures. All forward-looking statements are qualified in their entirety by this cautionary statement, and Kineta undertakes no obligation to revise or update any forward-looking statement to reflect events or circumstances after the issuance of this press release.
Kineta, Inc.
Meg O'Conor, Executive Director, Corporate Business Development, 206-251-8638
[email protected]


text:
Jump to: navigation, search
ALSA is a new digital sound architecture for linux and is meant to replace the OSS modules. It is now shipped with the 2.6.x kernel series. First, here are some related pages.
Alsa consists of several layers:
alsa-lib - is a userspace library that provides a level of abstraction over the kernel modules. For audio devices there's the "pcm" and "ctl" abstractions. For midi, the "seq" interface is avaliable. See the alsa-lib docs for more details.
user space programs - there's some user space programs provided like the aforementioned aconnect. An incomplete List [please fill missing in]:
So summing it up. ALSA is the superior sound architecture compared to OSS. Lack of drivers is a problem though. But Linux is gaining momentum, so maybe hardware producers start to be more generous on card documentation. If you want to use serious Low-Latency recording with Linux and ALSA, you need to patch your kernel with Low-Latency patches and install jackd. Then rock solid operation is very much possible. There's a cool jack hard disk recorder called ardour. There's several native alsa-sequencers like muse and rosegarden. There's all kinds of softsynths for jack like SpiralModularSynth and amSynth... Check the linux audio pages for more. Hope to have cleared up some stuff. Feel free to modify improve and correct my little text here..
After successfully installing ALSA, I was trying to get it to start automatically at boot time, using '/etc/init.d/alsasound' service start script (put there by the ALSA installation) but found I had 2 problems, one was that the format of the sound modules in the ALSA HOWThs is different from what the alsasound startup script expects, second that grep -E was not working as (I) expected. For some reason it was not correctly working with \^ (start of line marker) in its regexp used to match the ALSA lines in '/etc/modules.conf'. What I had to do was alter one line in the alsasound script to fix both problems.
Here is the line as it was
grep -E "^space:*aliasspace:+snd-card-digit:" | \
and as it is now
grep -E "alnum:*space:+snd-card-digit:$" | \
And here is my '/etc/module.conf' (ALSA portion, my sound card is an ESS
SOLO1 which uses the snd-es1938 module)
# ALSA setup of ESS SOLO-1
alias char-major-116 snd
alias snd-card-0 snd-es1938
# OSS/Free setup
alias char-major-14 soundcore
alias sound-slot-0 snd-card-0
alias sound-service-0-0 snd-mixer-oss
alias sound-service-0-1 snd-seq-oss
alias sound-service-0-3 snd-pcm-oss
alias sound-service-0-12 snd-pcm-oss
Some cards (es1370, es1371, etc) have a second pcm playback device that the OSS drivers traditionally access as /dev/dsp1 (major 14, minor 19). With ALSA this second pcm output is accessable with oss compatability enabled as /dev/adsp (major 14, minor 12). This device is very useful to get a nonblocking artsd or esd sound daemon. Many distros will not create the /dev/adsp device for you so you will have to execute "cd /dev; mknod adsp c 14 12". If you are using devfs this device will be automaticaly created by devfsd.
JoernNettingsmeier posted an .asoundrc to linux-audio-users to use two cards as one.
First install alsa-driver. After that alsa-library and finally the other packages. Detailed installation instruction can be found in the INSTALL file (included in each package). See Quick Install.
Patrick Shirkey has collected some information about fixing Unresolved Symbols
The .asoundrc file allows more sophisticated control over your audio card and some very useful applications will not work at all without it. A system wide version can be installed as /etc/asound.conf and a more specific version stored in your home directory as \$HOME/.asoundrc. Until now, it has been a bit of a black art getting the details correct.
A brief example
Put the following in a file in your home directory named .asoundrc:
pcm.myfirstcard {
type hw
card 0
pcm.!default myfirstcard
From Dave Andruczyk: For those not so well versed in ALSA if you install 0.9beta 11 over a previous release, make sure you DELETE the /lib/modules/YOUR_KERNEL/misc/snd* modules. The beta 11 version reorganizes the ALSA kernel drivers in a much better and cleaner format, under /lib/modules/YOUR_KERNEL/kernel/sound/ ALSO (I didn't check the docs), but if your module was "snd-card-xxxxx" its now snd-xxxxx. Thus the older snd-card-emu10k1, is now snd-emu10k1. So edit your /etc/modules.conf as appropriate and things should be just fine. Make sure to run "depmod -a" after modifying /etc/modules.conf, or after deleting/adding kernel modules to your modules tree under /lib/modules/YOUR_KERNEL Aside from that beta 11 works wonderfully on my box (Mandrake 8.1).
For those of you who use ALSA on the 2.4 kernel, you may also use devfs, which is a dynamic device filesystem which allows for the creation of device entries on the fly. However, this can cause problems when moving from OSS to ALSA on a 2.4 devfs system. Here are some example entries which may help (these come from my own setup):
REGISTER snd/.* PERMISSIONS root.games 666
REGISTER sound/.* PERMISSIONS root.games 666
LOOKUP sound/audio EXECUTE mknod -m 666 sound/audio c 14 4
LOOKUP sound/dsp EXECUTE mknod -m 666 sound/dsp c 14 3
LOOKUP dsp EXECUTE mknod -m 666 dsp c 14 3
REGISTER sound/mixer MKOLDCOMPAT
If you use devfs interface for /dev, you cannot use the 2nd or later card with the original sound_core.c on 2.4 kernel. if you use proc interface for /dev/snd, it works anyway. You can have multiple soundcard with devfs using a patched sound_core.c:
patch /usr/src/linux/drivers/sound_core < wget -q -O - \ http://hypermail.idiosynkrasia.net/linux-kernel/archived/2001/week50/att-0144/01-sound_core.c.dif
also if you build the kernel without devfs support and use 2nd or later cards, then you'll get annoying error messages, even if you use proc interface. (it's harmless, though.)
Incorrect advice... should have been "chmod 666 /dev/snd/*". And to compliment this insecure setting the directory itself needs to be "chmod 755 /dev/snd".
This may not work because often, on a non-devfs enabled system, /dev/snd is symlinked to /proc/asound/dev where the permission cannot be manually modified. The most reliable way to change the owner/permission is to pass a proper module option to snd.o when ALSA starts up in /etc/modules.conf with a line similar to...
options snd snd_major=116 snd_cards_limit=4 \
snd_device_mode=0660 snd_device_gid=29 snd_device_uid=0
Writing a proc file is really easy. you can simply copy the code from
one of the driver. But the proc info, such as usb descriptor dump, is
hardware (driver) dependent. It's up to the driver author. so I cannot
summarize the "general" usage for such files. Ok, let me comment major
proc files...
/proc/asound/cards (RO)
the list of registered cards
/proc/asound/version (RO)
the version and date the driver was built
/proc/asound/devices (RO)
the list of registered ALSA devices (major=116)
/proc/asound/hwdep (RO)
the list of hwdep (hardware dependent) controls
/proc/asound/meminfo (RO)
memory usage information
this proc file appears only when you build the alsa drivers
with memory debug (or full) option so the file shows the
currently allocated memories on kernel space.
/proc/asound/pcm (RO)
the list of allocated pcm streams
the directory containing device files. device files
are created dynamically.
in the case without devfs, this directory is usually
linked to /dev/snd
the directory containing info about oss emulation
the directory containing info about sequencer
/proc/asound/cardX (X = 0-7)
the card-specific directory
Generally the file is named as aaaCxDy, where aaa is the service name, x
the card number (0-7) and y the device number (0-).
controlC? control devices (i.e. mixer, etc.)
hwC?D? hwdep devices
midiC?D? rawmidi devices
pcmC?D?p pcm playback devices
pcmC?D?c pcm capture devices
seq sequencer device
timer timer device
The contents of the files under this directory are changed dynamically.
when no oss emulation modules (snd-pcm-oss, snd-mixer-oss) are loaded,
no pcm nor mixer devices will be listed.
/proc/asound/oss/devices (RO)
the list of devices already registered
/proc/asound/oss/sndstat (RO)
/dev/sndstat compatible list
id (RO)
the id string of the card
ac97#? (RO)
AC97 codec information
ac97#?regs (RO)
(printable) register dump
midi? (RO)
the current status of input/output on the
rawmidi device
the directory status of the given pcm playback stream
the directory status of the given pcm capture stream
PCM stream information
pcm??/info (RO)
the pcm stream general info (card, device, name, etc.)
pcm??/oss (RO)
oss emulation info (shown only when the pcm is opened
as an oss device).
the substream information directory
pcm??/sub?/info (RO)
the pcm substream general info (card, device, name, etc.)
pcm??/sub?/status (RO)
the current status of the given pcm substream
(status, position, delay, tick time, etc.)
pcm??/sub?/hw_params (RO)
hw_params set-up on the substream
(buffer size, format, etc.)
pcm??/sub?/sw_params (RO)
sw_params set-up on the substream
(threshold, etc.)
pcm??/sub?/prealloc (RW)
the number of pre-allocated buffer size in kb.
you can specify the buffer size by writing to this proc file:
# echo 128 > /proc/asound/card0/pcm0p/sub0/prealloc
to allocate 128kbyte for playback, substream #0, stream #0
on the card #0.
To find all the options for the alsa modules on your machine run this script...
modinfo $(modprobe -l snd-*) | cat > ~/modinfo
snd_* settings for the OPL3-SA in the Toshiba SP490XCDT and similar. Look up the current sound settings in the BIOS setup:
Write down the sound settings (Description in YaST, option name):
Start Linux, YaST
Some notes on compiling ALSA modules for Debian (you may need to do ./configure after unzipping ALSA), another example and yet another howto on the same subject.
NEWS FLASH! Jaroslav's dmix plugin comes to the rescue! See the DmixPlugin wiki page. Since ALSA 0.9.1 it has been possible to use the dmix plugin to share a single device with multiple applications. This was a puzzling omission from previous ALSA releases, and a big thanks go out to Jaroslav for implementing this. Please note that the 'share' plugin, as indicated in various places, is useless for this task. The ALSA documentation includes an 'Unknown Reference' to this software mixer ('smix', or 'pcm_mix') plugin, and should probably be updated with the information that this plugin is not part of the current ALSA tree, and will not be without a lot of work. This plugin has been replaced in functionality with 'dmix'
I will provide details on how to configure this plugin as part of the 'default' ALSA sound path when I figure out how to do it. Here's the best documentation of dmix that exists at the moment:
This is how you set your card to use the dmix plugin by default:
pcm.!default {
type plug
slave.pcm "dmix:CARD=0,DEVICE=0,RATE=48000"
awk '/^snd/||/^sound/&&($3==0){system("rmmod " $1)}' /proc/modules /proc/modules /proc/modules
Since RedHat doesn't use devfs, you will need to run ./snddevices during
install, no matter which version you are installing. The problem I was
having is that atempting to run alsamixer resulted in the error:
alsamixer: function snd_ctl_open failed for default: \
No such file or directory
so if you're on another distro and having the above problem you may want to give ./snddevices a try. And where do I find snddevices? http://cvs.sourceforge.net/viewcvs.py/*checkout*/alsa/alsa-driver/snddevices.in
Have alook at the output of cat /proc/asound/devices.
1: : sequencer
0: [0- 0]: ctl
8: [0- 0]: raw midi
18: [0- 2]: digital audio playback
17: [0- 1]: digital audio playback
16: [0- 0]: digital audio playback
24: [0- 0]: digital audio capture
33: : timer
On my system there's 3 playback devices. If i want to make the third the default i just add this line to my \~/.asoundrc [counting starts at 0]:
defaults.pcm.device 2
This selects hw:0,2 as the defaul pcm device.. I figure this might make trouble when trying to record. But then jut use hw:0,0 as the capture device [the setup of your software should allow that]. It works here.
You have to override the definition of pcm.dsp0 and ctl.dsp0 like this
\~/.asoundrc and then use the aoss script from
the alsa-oss package:
pcm.dsp0 {
type hw
card 0
device 2
ctl.mixer0 {
type hw
card 0
The above pcm definition makes the OSS emu use the 2nd device on the first card [which is in my case the digital out]
I thought this is the place where i can share this, if not please move it! Ok to the point I have Realtek ALC655/AC'97 card on my gigabyte mobo, the card has 3 stereo-jacks - out, mic-in and line-in. The problem was that there is no app for making mic-in and line-in behave like outputs (this card is 5+1 channels) so that I can plug 6 speakers.. i made alot of asking and searching w/o an answer even on the ALSA list.. the solution was prety damn easy. I just had to use "\<" and ">" for :
Mic As Center/LFE
Line-In As Surround
instead of arrows, with which u normaly increase the volume... Below is
a description how to do this manualy with amixer (u may need this too to
include in scripts).. Ok here is it :
#amixer | grep -A 3 As
Simple mixer control 'Line-In As Surround',0
Capabilities: pswitch pswitch-joined
Playback channels: Mono
Mono: Playback [off]
Simple mixer control 'Mic As Center/LFE',0
Capabilities: pswitch pswitch-joined
Playback channels: Mono
Mono: Playback [off]
#amixer cset iface=MIXER,name='Line-In As Surround',index=0 95%
numid=37,iface=MIXER,name='Line-In As Surround'
; type=BOOLEAN,access=rw---,values=1
: values=on
#amixer cset iface=MIXER,name='Mic As Center/LFE',index=0 95%
numid=38,iface=MIXER,name='Mic As Center/LFE'
; type=BOOLEAN,access=rw---,values=1
: values=on
#amixer | grep -A 3 As
Simple mixer control 'Line-In As Surround',0
Capabilities: pswitch pswitch-joined
Playback channels: Mono
Mono: Playback [on]
Simple mixer control 'Mic As Center/LFE',0
Capabilities: pswitch pswitch-joined
Playback channels: Mono
Mono: Playback [on]
This is pretty much the reverse of the above post where you want a single output (line-out) to have the full range out sound, not splitting the sound across all the potential outputs. Useful if you only use your machine with headphones.
Sometimes the alsamixer settings needed to control recording are not obvious, and recording may not be working, recording noise or "snow." Before complaining that the driver is broken (as I just about did), try this sensible recipe from Kai Vehmanen, author of the excellent ecasound system. In one console, issue the command:
arecord -r 48000 -c 1 | hexdump
In another console, issue the command:
In the first console, you should see bytes scrolling by. If they are very repetitive, they are probably noise or something you don't want. In the mixer window, change various mixer settings that are likely to affect the recording. In my case, pressing the Insert key to toggle off IEC958 capture was all I needed to get mic input working correctly. Then, changing Capture volume fine-tuned the input. In the first console window, I would press Ctrl-C and then arecord to a file, and then aplay the result to hear what it sounded like.
OK so you get ALSA up and running, but the sound is disturbed. For instance, playing mono 8bit sound is OK, but stereo is just messed up. Or you always get some humming background noise. Leaving alone things you can do with the driver itself (another parameters etc) here is what you can try:
Another thing you can try:
Reload the alsa sound modules. Attention: Most often the /etc/init.d/alsa script won't do that. You have to use the script alsasound which comes with the alsa packages in that case: Simply run /etc/init.d/alsasound restart and in two cases (cmipci and cs46xx) it worked for me. Try the very same if recording gives you distortions or clippings (in my case SPDIF recording).
Retrieved from "http://alsa.opensrc.org/AlsaTips"


text:
Microsoft lost the fifth-biggest patent judgment in U.S. history Wednesday in a case involving antipiracy software. A Rhode Island federal court jury slammed the software giant with a $388 million verdict for willfully infringing a patent owned by Uniloc Singapore Private Ltd. and Uniloc USA Inc.
The "product activation" feature in question prevents a single copy of a software program from being used on multiple computers by requiring users to register the software on a specific machine before using it.
Uniloc first filed suit in 2003, and last August the Federal Circuit reversed a lower court decision granting summary judgment to Microsoft. The court remanded the case, and the trial began in late March.
"We are very disappointed in the jury verdict," Microsoft spokesman David Bowermaster said in a statement. "We believe that we do not infringe, that the patent is invalid and that this award of damages is legally and factually unsupported. We will ask the court to overturn the verdict."


text:
WILTSHIRE Police is appealing for information following a suspected arson in Purton.
The incident took place shortly after 10.30pm on January 11 at an unoccupied coach house on Long Acre, Purton.
A fire was started inside the property, which was undergoing significant building work at the time, causing significant damage.
Nearby CCTV shows four youths – three males and a female, enter the property and leave after the fire was started.
The first of the male youths was seen wearing a bobble hat, jacket and tracksuit bottoms. The second was wearing a jumper with a gilet or jacket with shoulder patches and a beanie hat. The third male was wearing a hooded top with black shoes.
The female was wearing a puffa-style jacket with darker clothes underneath. She had her hood up with a bobble hat under the hood. She was also carrying handbag and wearing trousers.
All of the youths appear to be under 18 years old.
Detective Sergeant Liz Coles from Swindon CID said: "Clearly, this incident has caused huge upset for the owners but at this stage we believe this appears to be a reckless act of vandalism rather than a personal attack.
"A detailed police investigation is underway, supported by Wiltshire Fire and Rescue Service, and I would urge anyone with information on the incident or anyone who thinks they recognise any of the people in CCTV footage to come forward.
"The smallest piece of information might prove vital in this investigation."
Anyone with information is asked to contact Wiltshire Police on 101 or Crimestoppers on 0800 555 111 where information can be left anonymously.


text:
This quote is hidden because you are ignoring this member. Show Quote
I am not making excuses for Roy. I am explaining reasons for his terrible play and poor demeanor.
Some people are able to shake off negativity and bad times more easily than others.
It would appear, at least on the basketball court, that Roy is not one of those people.
I pray that he is able to begin fighting against that label.


text:
What's your toddler's personality type?
Knowing this could impact your parenting style more than you realise. more
Getting your preschooler into bed long enough to fall sleep, can pose a challenge for many parents. But while there's no one right way to deal with sleep problems, there are many strategies you can try.
Some children get into the habit of repeatedly getting out of bed and coming out of their room every night until it seems your exhausting attempts to convince your overtired child to stay in bed each night is your new bedtime routine.
To put an end to this, you need to send your child a strong, silent message that there's no value in coming out of his room after bedtime because you're not going to give him any attention.
To do this, we suggest:
If you stick to this routine, he'll start staying in his room after you've had a cuddle and turned off the light. Sure, he may not stay in his bed, but as long as he stays in his room, you can count this as a victory.
This article was created for Kidspot - Australia's parenting resource for preschool


text:
Posted 5 years ago
(40 items)
These belonged to my Great Aunt. I remember her having them on the shelf when I was about 4 or 5 years old. Looking up and seeing them. Mom showed me the insides with the flour at that time and in the tea container was ? It do not recall but the coffee container had coffee. It was very strong smelling and I was not use to being around anyone who used such stuff and the smell was very strong.


text:
6243 results
IWOOT presents a range of groovy gifts under £20. Our unique and unusual gifts for men, women & children are wide-ranging and always competitively priced. Whether you're hunting for Father's Day gift ideas or looking for smaller birthday presents, IWOOT's gifts less than £20 are almost certain to delight the loved ones in your life. From Smartphone Projectors to Virtual Reality Headsets, Lightboxes to Mini Arcade Machines, these gifts under £20 just keep on giving! #wrapdifferent


text:
Ethics Blogs
Ethics Center staff and scholars offer regular commentary on current topics in a variety of fields.
All About Ethics
Staff in all Center program areas share their views on the ethical issues behind the news.
Internet Ethics: Views From Silicon Valley
Internet Ethics Director Irina Raicu comments on privacy, big data, access, and other issues.
Benison: The Practice of Ethical Leadership
Leadership Ethics Director Ann Skeet shares her analysis of leadership in business, sports, nonprofits, and other sectors.
The Big Q
SCU students reflect on the ethical issues in the everyday lives of undergrads.


text:
New York -- The Conference Board said Tuesday that its Consumer Confidence Index pulled back slightly in March, to 70.2, down from 71.6 in February.
"Consumer Confidence pulled back slightly in March, after rising sharply in February," said Lynn Franco, director of The Conference Board Consumer Research Center. "The moderate decline was due solely to a less favorable short-term outlook, while consumers' assessment of current conditions, on the other hand, continued to improve."
The Present Situation Index increased to 51.0 from 46.4, its highest level in three and a half years. The results, Franco said, suggest that despite this month's dip in confidence, consumers feel the economy is not losing momentum.
The Expectations Index declined to 83.0 from 88.4 in February as consumers became less optimistic about the short-term outlook. The proportion of consumers expecting business conditions to improve over the next six months increased to 19.2% from 18.9%. However, those anticipating business conditions will worsen also rose, to 13.5% from 11.8%.


text:
Being a music buff may look easy to the common observer - after all, what could possibly be challenging about going to a few gigs and spinning the odd record? Pah! These people know little of the blood, sweat and learning of rare B-sides that goes into being a serious musical connoisseur. To reach the peaks of music fandom can feel like a full-time job, involving hours of research, relentless one-upmanship and a delicate relationship with your own sanity. But then, nobody ever said being a music fan was supposed to be fun, right?
There's no point telling everyone about the new Frank Ocean album when everyone else has already moved on to raving over Miguel. As with Olympic events or making wisecracks on Twitter, being first is everything in this game.
If music buffery is your world then consider obscurity your currency. Nobody will be impressed by your suggestion to go seek out Abbey Road. A Transylvanian trip-hop collective that only formed last Wednesday, however...
Have you just rhapsodised about Justin Timberlake's excellent hip-hop productions only to be met with sniggers and "You mean Timbaland, right?" You could, of course, admit that you're clueless. Then again you could just shrug and say "Maybe you never heard those tracks..." before walking away, very quickly.
Frank Zappa is perhaps the only pop musician to have had an asteroid named after him: 3834 Zappafrank
Nas' intro to classic hip-hop track "NY State of Mind" - "I don't know how to start this" - was actually a mistake that ended up getting left in the finished version
Producer Bob Ezrin achieved the crying effect on Lou Reed's "The Kids" by telling his own children that their mother had died
While recording the ground-breaking What's Going On album, Marvin Gaye kept his thoughts political by allegedly masturbating for long periods between sessions
The reason Sly Stone's There's a Riot Goin' On has such a muddy, lo-fi sound is because the funk legend had to keep recording over the tapes after promising girls they could sing backing vocals


text:
Pediatric HIV/AIDS is a disease afflicting children as HIV can be transmitted during sexual intercourse, pregnancy (i.e., from mother to fetus), childbirth, breastfeeding, and other forms of exposure to bodily fluids that carry the virus. When the virus enters the body, it injects itself into vital immune cells called CD4 cells. In the absence of treatment, HIV continues to replicate itself within the body, eventually leading to severe immunodeficiency, chronic illness, and death.
The FDA Office of Orphan Products Development (OOPD) mission is to advance the evaluation and development of products (drugs, biologics, devices, or medical foods) that demonstrate promise for the diagnosis and/or treatment of rare diseases or conditions.
Orphan Drug Designation carries multiple benefits, including the availability of grant money, certain tax credits and seven years of market exclusivity, as well as the possibility of an expedited regulatory process.
Pediatric HIV/AIDS Surveillance Source CDC
Persons Living with Perinatally Acquired HIV Infection,
Year-end 2009—46 States and 5 U.S. Dependent Areas
Perinatally Infected Persons Living with an AIDS
Diagnosis, Year-end 2009—United States and
6 U.S. Dependent Areas
Perinatally Acquired HIV Infections in Children Born
During 2010—46 States and 5 U.S. Dependent Areas
Time of Maternal HIV Testing among Infants
with Perinatally Acquired HIV Infection,
Birth Years 2007–2010—46 States
Diagnoses of HIV Infection and Population in Children
Aged <13 Years, by Race/Ethnicity, 2010—46 States
Diagnoses of HIV Infection N = 217
"REMUNE is a wonderful treatment for HIV/AIDS and can benefit the pediatric population infected with this dreadful disease. IRBP will aim to bring REMUNE into the treatment arsenal for pediatric HIV/AIDS and give doctors the tools and ammunition they need to combat this life threatening disease. This is a great day for patients as IRBP moves closer to bringing REMUNE to commercialization. If i were big pharma i wouldn't get to confident or comfortable that REMUNE will be kept of the market much longer or that we won't secure funding. This is the beginning of the end of big pharma's reign over the HIV/AIDS market" Mr. Buswell CEO IRBP.
REMUNE is a therapeutic vaccine designed to elicit immune responses against a variety of HIV antigens in patients with HIV. It consists of a suspension of killed HIV-1 virus particles that have been emulsified with Incomplete Freund's Adjuvant (IFA, a mixture of mannide mono-oleate and a highly purified mineral oil).
REMUNE® is derived from Zairian HIV-1 strain HZ-321, composed of gp 120-depleted HIV-1 propagated in HUT-78 cells and inactivated in beta-propiolactone and irradiation. The inactivated material is emulsified with mineral oil (Incomplete Freund's Adjuvant) at 1:1 ratio. Each 1 ml dose (at least 100µg or 10 units) has viral protein and p24.
These previous clinical studies of REMUNE®have demonstrated distinct benefits in both immunologic and virologic parameters in HIV-1 infected individuals undergoing treatment. Subjects undergoing treatment with REMUNE®showed improvements in percentage of CD4 cells, HIV-1 DNA in PBMCs, and weight. Previous studies also indicate that REMUNE®can safely be given in combination with antiviral drugs.
IR103/Remune,unlike antiviral drugs, can induce an HIV-specific response, which is now thought by numerous researchers to be important in controlling HIV replication. Remune has been administered to over 2,000 patients in over 25 separate clinical trials, has an excellent safety profile, is well tolerated and is easy to administer via intramuscular injection in the deltoid muscle.
Data from clinical trials of Remune suggest that it may:
Induce a HIV-specific T-cell response; work in Patients with Multi-Drug Resistance
Induce cytokines and chemokines, substances that interfere with the virus attaching to and infecting normal cells;
Work with antiretroviral drugs as a complementary treatment for HIV infection;
Work in drug-naïve patients to delay the need for initiation of HAART; and
Be safe with no adverse side effects, Reduce Viral Load, Increase CD4+ T cells & CD8+ T Cell Counts
Immune Response BioPharma, Inc. Maybe Found on the World Wide Web @ www.immuneresponse.net