text:
Current Highlights on Broadway
Find a show or venue
Order by phone
Your independent guide to the best shows in New York
165 Mulberry Street, Newark, NJ 07102
Ended 24 Nov 2013 after 4 days
The ice skating was impressive and throughout the performance the characters interacted with the audience making for a fun experience.
Northeast Ohio Family Fun.com
Take a look here to see if Disney On Ice: Let's Celebrate is showing somewhere nearby
Disney On Ice presents Let's Celebrate!, a show all about celebrations from across the globe! Disney characters new and old join the fun, with the show marking the skating debut of Princess Tiana and Prince Naveen from Walt Disney's modern classic The Princess and The Frog.
Classic and contemporary Disney songs, an original storyline, brilliant costumes and high energy action will have audiences celebrating some of the world's most popular events without ever leaving their seat - from Halloween with the Disney Villains, to a Valentine's Day Royal Ball featuring the Disney Princesses. In a fun-packed, ice extravaganza, more than 50 characters from 16 Disney stories will converge and take audiences on a thrilling world tour to exotic destinations, including Brazil for a Carnivale parade, Hawaii for a luau party and Japan for a Cherry Blossom festival.
Disney On Ice: Let's Celebrate! is on tour and hits the Prudential Center in Newark, NJ, Ended 24 Nov 2013.
Opening night: 20 November 2013
Closing night: 24 November 2013
Nobody is too young, or too old for Disney On Ice. If your child is under 2 years old you don't need to buy a ticket.
2 hours and 15 minutes, including one intermission
2 reviews, average rating: (1.2 Stars)
Ellen Moschella: "Where's The Disney Music?"
Disappointed in the lack of Disney music. Did not feel it was the quality o... more
Patrick Murphy: "Canceled Show With No Heads Up "
Saturday Nov. 23, 2013 apparently canceled without any heads up to ticket h... more
Please note: The term Prudential Center and/or Disney On Ice: Let's Celebrate as well as all associated graphics, logos, and/or other tradermarks, tradenames or copyrights are the property of the Prudential Center and/or Disney On Ice: Let's Celebrate and are used herein for factual descriptive purposes only. We are in no way associated with or authorized by the Prudential Center and/or Disney On Ice: Let's Celebrate and neither that entity nor any of its affiliates have licensed or endorsed us to sell tickets, goods and or services in conjunction with their events.


text:
Temsirolimus in Treating Patients With Recurrent or Persistent Cancer of the Uterus
- Full Text View
- Tabular View
- Study Results
- Disclaimer
- How to Read a Study Record
|Recurrent Uterine Sarcoma Uterine Carcinosarcoma
|Drug: temsirolimus
|Phase 2
|Study Type:
|Study Design:
|Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
|Official Title:
|Pilot Phase II Study of Temsirolimus in Patients With Recurrent Mixed Mesodermal and Mullerian Tumors (Carcinosarcoma) of the Uterus
- Tumor Response Rate, in Terms of the Proportion of Confirmed Tumor Responses (CR or PR) Assessed Using RECIST [ Time Frame: Up to 3 years ]
- Progression Free Survival [ Time Frame: 6 months from registration ]The 6-month progression-free rate is defined as the total number of efficacy-evaluable patients on study without documentation of disease progression 6 months from registration divided by the total number of efficacy-evaluable patients enrolled on study.
- Overall Survival [ Time Frame: From registration to death, assessed up to 3 years ]Time to event distributions will be estimated using the Kaplan-Meier method.
- Duration of Response, Defined for All Evaluable Patients Who Have Achieved an Objective Response as the Date at Which the Patient's Objective Status is First Noted to be Either a CR or PR to the Date Progression is Documented [ Time Frame: Up to 3 years ]Median duration of response and the confidence interval for the median duration will be computed.
- Time to Treatment Failure [ Time Frame: From study registration to the date patients end treatment, assessed up to 3 years ]Time to treatment failure will be evaluated using the method of Kaplan-Meier.
- Time to Progression [ Time Frame: Time to progression is defined as the time from registration to disease progression. ]
|Study Start Date:
|January 2010
|Study Completion Date:
|October 2012
|Primary Completion Date:
|April 2012 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: Treatment (temsirolimus)
Patients receive temsirolimus IV over 30 minutes on days 1, 8, 15, and 22. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity.
Drug: temsirolimus
Given IV
Other Names:
Detailed Description:
I. Assess the efficacy of Temsirolimus in women with recurrent or persistent (after primary therapy) Carcinosarcoma (MMMT) of the uterus.
II. Assess the safety and tolerability of Temsirolimus in this patient population.
III. Evaluate secondary efficacy endpoints of time to tumor progression, progression-free survival (PFS), 6 month PFS rate, and duration of response.
I. Overall survival II.Duration of Response III. Time to progression IV. Time to treatment failure
OUTLINE: This is a multicenter study.
Patients receive temsirolimus IV over 30 minutes on days 1, 8, 15, and 22. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity.
After completion of study therapy, patients are followed up periodically for up to 3 years.
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Histologically or cytologically confirmed Carcinosarcoma (MMMT)
- Measurable disease;
- Only one prior systemic treatments after primary adjuvant treatment for persistent or metastatic disease are permitted,
- Radiation therapy (adjuvant or palliative) must be completed ≥ 4 weeks prior to registration
- Required laboratory values obtained =< 7 days prior to registration:
- Absolute Neutrophil Count (ANC) >= 1500/mm^3
- Platelets >= 75,000/mm^3
- Hemoglobin >= 9.0 g/dL
- Direct bilirubin =< 1.5 x upper limit of normal (ULN)
- Alkaline phosphatase =< 2.5 x ULN (≤ 5 x ULN if liver metastasis is present)
- SGOT(AST) =< 2.5 x ULN (≤ 5 x ULN if liver metastasis is present)
- Creatinine =< 1.5 x ULN
- Fasting serum cholesterol ≤ 350mg/dL (9.0 mmol/L)
Triglycerides ≤ 1.5 x ULN
- Patients with Triglyceride levels > 1.5 x ULN can be started on lipid lowering agents and reevaluated within 1 week; if levels go to ≤ 1.5 x ULN, they can be considered for the trial and continue the lipid lowering agents
- International Normalized Ratio (INR) ≤ 1.5 (unless the patient is on full dose warfarin)
- ECOG Performance Status (PS) 0-1
- Capable of understanding the investigational nature, potential risks and benefits of the study and able to provide valid informed consent
Full-dose anticoagulants, if a patient is receiving full-dose anticoagulants, the following criteria should be met for enrollment:
- The subject must have an in-range INR (usually between 2 and 3) on a stable dose of warfarin or on stable dose of LMW heparin
- Patients who have had prior anthracycline must have a normal ejection fraction on LVEF assessment by MUGA or Echo ≤ 4 weeks prior to registration
- Availability of tissue samples or blocks (from the primary tumor or metastases) for tumor studies
- Willingness to donate blood for correlative marker studies
Exclusion Criteria:
- Prior therapy with Temsirolimus or another mTOR inhibitors
- Patients cannot be receiving enzyme-inducing antiepileptic drugs (EIAEDs; e.g., phenytoin, carbamazepine, phenobarbital) nor any other CYP3A4 inducer such as rifampin or St. John's wort
Untreated central nervous system (CNS) metastases; exceptions: patients with known CNS metastases can be enrolled if the brain metastases have been adequately treated and there is no evidence of progression or hemorrhage after treatment as ascertained by clinical examination and brain imaging (MRI or CT) ≤ 12 weeks prior to registration and no ongoing requirement for steroids
- Anticonvulsants (stable dose) are allowed
- Patients who had surgical resection of CNS metastases or brain biopsy ≤ 3 months prior to registration will be excluded
- Pregnant or lactating wome
- Currently active, second malignancy other than non-melanoma skin cancers; - Other uncontrolled serious medical or psychiatric condition (e.g. cardiac arrhythmias, diabetes, etc.)
- Active infection requiring antibiotics
- Received prior radiotherapy to any portion of the abdominal cavity or pelvis OTHER THAN for the treatment of endometrial cancer
- Radiation therapy to > 50% of marrow bearing areas
Please refer to this study by its ClinicalTrials.gov identifier: NCT01061606
|United States, California
|Tower Cancer Research Foundation
|Beverly Hills, California, United States, 90211-1850
|City of Hope
|Duarte, California, United States, 91010
|Los Angeles County-USC Medical Center
|Los Angeles, California, United States, 90033
|City of Hope Medical Group Inc
|Pasadena, California, United States, 91105
|University of California at Davis Cancer Center
|Sacramento, California, United States, 95817
|United States, Connecticut
|University of Connecticut
|Farmington, Connecticut, United States, 06030
|Yale University
|New Haven, Connecticut, United States, 06520
|United States, New Jersey
|Morristown Memorial Hospital
|Morristown, New Jersey, United States, 07962
|The Valley Hospital-Luckow Pavilion
|Paramus, New Jersey, United States, 07652
|United States, New York
|Women's Cancer Care Associates LLC
|Albany, New York, United States, 12208
|Montefiore Medical Center - Moses Campus
|Bronx, New York, United States, 10467-2490
|Beth Israel Medical Center
|New York, New York, United States, 10003
|New York University Langone Medical Center
|New York, New York, United States, 10016
|Saint Luke's Roosevelt Hospital Center - Roosevelt Division
|New York, New York, United States, 10019
|Presbyterian-Weill Medical College
|New York, New York, United States, 10021
|Mount Sinai School of Medicine
|New York, New York, United States, 10029
|Children's Hospital of New York Presbyterian
|New York, New York, United States, 10032
|Columbia University College of Physicians and Surgeons
|New York, New York, United States, 10032
|United States, Pennsylvania
|Penn State Hershey Children's Hospital
|Hershey, Pennsylvania, United States, 17033
|United States, Texas
|University of Texas Health Science Center at San Antonio
|San Antonio, Texas, United States, 78229
|Principal Investigator:
|Mark Einstein
|Montefiore Medical Center - Moses Campus
|Responsible Party:
|National Cancer Institute (NCI)
|ClinicalTrials.gov Identifier:
|NCT01061606 History of Changes
|Other Study ID Numbers:
NCI-2012-02989 ( Other Identifier: CTRP (Clinical Trial Reporting Program) )
8167 ( Other Identifier: CTEP )
N01CM00038 ( U.S. NIH Grant/Contract )
P30CA013330 ( U.S. NIH Grant/Contract )
|Study First Received:
|February 2, 2010
|Results First Received:
|September 21, 2016
|Last Updated:
|September 21, 2016
Additional relevant MeSH terms:
Mixed Tumor, Mullerian
Uterine Neoplasms
Neoplasms, Complex and Mixed
Neoplasms by Histologic Type
Neoplasms, Connective and Soft Tissue
Genital Neoplasms, Female
Urogenital Neoplasms
Neoplasms by Site
Uterine Diseases
Genital Diseases, Female
Antineoplastic Agents
Immunosuppressive Agents
Immunologic Factors
Physiological Effects of Drugs
Anti-Bacterial Agents
Anti-Infective Agents
Antibiotics, Antineoplastic
Antifungal Agents
ClinicalTrials.gov processed this record on September 21, 2017

subset: commoncrawl


text:
EIGHT Oxfordshire businesses are to get £3.6m of funding from the Government's Growing Places Fund.
The fund is being made available to businesses to spend on buildings, refurbishment, new facilities and infrastructure projects.
Oxfordshire Local Enterprise Partnership (LEP), launched in 2011 to boost the local economy, is allocating the funding on behalf of the Government.
The partnership received 20 bids totalling £16m for the £3.6m pot of funding allocated by the Government to Oxfordshire.
LEP board member Ann Ducker, who is leader of South Oxfordshire District Council, said: "We have been able to offer valuable funding to local businesses at a time when it is extremely difficult for them to raise finance from the open market.
"The offers we have made will breathe life into a number of exciting projects that some businesses have had to put on hold, but which promise to boost to their growth and, importantly, to allow them to take on more staff."
Companies being offered funding include MEPC, which runs Milton Park business park.
It plans to upgrade a road junction at the entrance to Milton Park to improve access for businesses and residents of neighbouring villages.
Money is also being offered to Harwell Oxford, which plans to improve cycle lanes at their campus site. The other six potential recipients, and the amounts, have not been revealed.
The majority of applications came from small to medium-sized companies with plans to expand their businesses.
The LEP is supporting a separate county council bid for £11.5m of Government pinch-point funding to create a hamburger roundabout at the Milton Interchange.
- For further information visit oxfordshirelep.org.uk


text:
Right people at the right time
Related topics
The tight labour market has heightened the need for companies to attract, develop and retain highly-skilled workers. Michael Kunkle, principal consultant for Right Management Hong Kong, finds himself on the frontline of the battle. Rick Gangwani talks with him about the state of the industry, the 'human age' and being in the zone
What are the areas of talent management in which your company specialises?
We mainly focus on five key areas: leader development, organisational effectiveness, employee engagement, outplacement services, workforce transition and talent assessment, which includes one of the hot topics in Asia right now - sales team effectiveness.
What are some of the other 'hot topics'?
One of the big things that people are asking for in Hong Kong and Greater China right now is high potential programmes. They want to retain and develop their top talent. Manpower Group has actually done a lot of research in this area, and even helped coin the phrase 'the human age'.
What is 'the human age'?
This refers to the transition from an era of capitalism - where if you had money, you could grow - to an era where the pivotal thing that allows you to grow is your talent. Capitalism, we're saying, has been replaced by 'talentism', where whoever has the best people, and can hold on to them, is going to be the winner.
What does your role involve?
My role is to build up the capability of our consultants in the Hong Kong and Asia-Pacific region. I'm doing that in two ways. First, by building up the capabilities of our existing consultants through training and development. And second, by hiring additional consultants. Like our clients, we are growing our operations and finding ourselves in a position where there's a lot of work in the marketplace.
What does one need to be a consultant?
Experience in human capital consulting, or 10 years' experience in a senior-executive HR [human resources] role.
How would you describe the ideal consultant in terms of ability?
One who is able to quickly assess situations using data and, based on their industry knowledge and experience, can listen and partner with a client to develop successful talent management solutions.
How have attitudes towards talent management changed in Hong Kong over the years?
I can tell you with great confidence that one of the things we're seeing is an increase in the education level and sophistication of our customers. Five years ago, our primary point of contact would be someone in the HR department. Our primary contact these days is the C-suite - the CEO, CFO or, in many cases, the board. They absolutely get how important having a talent management strategy is for succeeding in business. We have a much more educated buyer at a much higher level in the organisation than ever before.
Do you see the need for your services increasing over the next few years?
Absolutely. The talent crunch that we're going through is only going to get worse. In Hong Kong and China, there are a couple of very specific things happening that are troubling, the most notable being the tendency among [job] candidates to choose Chinese companies over foreign ones. That's creating a unique situation, one that combines with the existing shortage.
In addressing this need, how will Right Management strive to differentiate itself from competitors?
Our primary advantage is our ability to customise leadership solutions. We also focus every engagement on identifying, as clearly as possible, what the ROI [return on investment] is on all our initiatives. We come up with clear metrics so that all of our actions can be linked to specific business results.
Do you have any worries or concerns in terms expansion?
My only concern is our ability to continue growing and to overcome the same challenge our clients have - that of having the right people, in the right place and at the right time.
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text: Offer valid beginning January 24, 2013, through January 29, 2013, on all approved orders placed online at our website, Abercrombie.com. To qualify, merchandise total must be over $100 and orders must be shipped within the US via Standard service. Discount will be taken automatically at checkout. Not valid on previous orders. Not redeemable for cash or store credit. Other restrictions may apply.


text:
Avery® Flexi-View™ Presentation Book 47690, Black, 24-Page BookProduct Number: 47690
Create high-quality, professional presentations in mere minutes. This Flexi-View™ Presentation Book features a patented view window to frame your custom-made title page. The pre-printed design looks professional for any business use, and twenty-four clear polypropylene pockets protect the pages of your presentation, but won't lift the print from them. With free templates available at avery.com to get you started, it's even easier to deliver a presentation that's dressed to impress.
Product Description:
Reviewed by 1 customer
This review is from Flexi-View 6-Page Presentation Book 47691:
I use these for client copy tax returns. I can put all the returns and the supporting documents in and they stay secure.


text:
Hurdle uses first challenge vs. Red Sox
FORT MYERS, Fla. -- Pirates manager Clint Hurdle on Wednesday night used the new replay system for the first time, challenging an inning-ending out at second base against the Red Sox.
With one out and a runner on second in the top of the seventh, Pirates outfielder Jaff Decker roped a comebacker to Red Sox pitcher Burke Badenhop. Badenhop spun and fired behind the runner at second base, catching pinch-runner Michael Martinez in a rundown between second and third base.
Red Sox third baseman Will Middlebrooks tagged out Martinez, then sprinted toward second base and dived to tag out Decker, who was trying to advance to second during the rundown. Second-base umpire Fieldin Culbreth ruled Decker out on the play and, after a brief review, the call was upheld.
Paul Casella is a reporter for MLB.com. Follow him on Twitter @paul_casella. This story was not subject to the approval of Major League Baseball or its clubs.


text:
Here's a little piece of sunshine in the form of an iPhone App. Launch Barcodas and scan a barcode into it using the iPhone's camera. It will turn the barcode into a musical sequence. You can change the tempo of your new audio sequence and share it on Facebook. Now I finally have something to do other than filling my cart while shopping in the supermarket.
"The barcodas app scans any ean (8 or 13) or upc (e or a) barcode and turns it into a musical pattern in a user-selectable harmonic scale. Imagine walking into a supermarket filled with thousands of tunes to discover, supermarket symphony! Share the barcodes you love listening to on Facebook, so all your barcodas friends can scan them too." – nr74.org/barcodas.html
For more info: nr74.org/barcodas.html


text:
Bochy: Giants must play well at home down stretch
SAN FRANCISCO -- Manager Bruce Bochy's guess is as good as anybody's.
He can't explain why the Giants entered Saturday 30-32 at AT&T Park. He's also confused by Madison Bumgarner's home/road splits (5.17 ERA/1.72), and Buster Posey hitting .239 at home compared to .328 on the road doesn't make much sense to Bochy, either.
"I think it's just one of those years," Bochy said. "We've had some play at home here that's been hard to explain, whether it's individual players or us as a team."
One thing that doesn't need explaining is that the clock's ticking, and time's running out for a turnaround.
With their disheartening 5-3 loss in 10 innings on Friday night, the Giants have lost 15 of their last 22 home games. With 41 games left, they finished Friday 5 1/2 games behind the National League West-leading Dodgers, a half-game behind the Pirates for the second NL Wild Card spot and 1 1/2 games behind the Cardinals for the first NL Wild Card spot.
"We're still in striking distance," Bochy said. "That's how good we were in the first half, and thank goodness that we did play such great ball for most of the first half."
The Dodgers haven't exactly run away with the division, and have recently been hampered by injuries. That'll all be irrelevant unless the Giants start resembling the team they were in the season's first two months more than the team they've been for the last two months.
"It doesn't matter what happens if we don't pick up our play at home, it's not going to matter what happens with the other clubs," Bochy said. "We've just got to control what we can, and that's how we play.
"This is the sprint."
Ryan Hood is an associate reporter for MLB.com. Follow him on Twitter @ryanhood19. This story was not subject to the approval of Major League Baseball or its clubs.


text:
IRVINE – A cement truck overturned and blocked traffic lanes on the southbound 73 Tuesday morning.
The apparent single-vehicle crash was reported at 10 a.m. north of Jamboree Road, the California Highway Patrol said. The Nos. 2 and 3 lanes were blocked and have since then cleared.
CHP officer Denise Quesada said it was unclear if the driver was injured. According to witness reports, the driver was seen walking around and did not appear injured.
Caltrans crews were dispatched to help clean up the scene, Quesada said.


text:
16 U.S. Code § 1a–7a - National Park System crime prevention assistance
prev | next
(a) Availability of funds
There are authorized to be appropriated out of the Violent Crime Reduction Trust Fund, not to exceed $10,000,000, for the Secretary of the Interior to take all necessary actions to seek to reduce the incidence of violent crime in the National Park System.
(b) Recommendations for improvement
The Secretary shall direct the chief official responsible for law enforcement within the National Park Service to—
(2)make recommendations concerning capital improvements, and other measures, needed within the National Park System to reduce the rates of violent crime, including the rate of sexual assault; and
(c) Distribution of funds
Based on the recommendations and list issued pursuant to subsection (b) of this section, the Secretary shall distribute the funds authorized by subsection (a) of this section throughout the National Park System. Priority shall be given to those areas with the highest rates of sexual assault.
(d) Use of funds
Funds provided under this section may be used—
(2)to provide emergency phone lines to contact law enforcement or security personnel in areas within or adjacent to National Park System units;
(3)to increase security or law enforcement personnel within or adjacent to National Park System units; or
Source(Pub. L. 91–383, § 13, as added Pub. L. 103–322, title IV, § 40132,Sept. 13, 1994, 108 Stat. 1917.)
LII has no control over and does not endorse any external Internet site that contains links to or references LII.


text:
Wee Society Art For Kids
Wee Society's Modern Art For Happy Families
Wee Society's Modern Art For Happy Families
Founded by a trio of San Francisco-based moms and dads, Wee Society merges seriously cool design with smart, interactive, and fun art, toys, and apps for — you guessed it — wee ones. "We believe bright little minds deserve really smart ideas," is just one component of the brand's mantra. They've recently partnered with Art.com to offer an exclusive range of prints, decals, and more to appease all sorts of spaces and price points.
Click through and explore all of the happy happenings over at Wee Society — interactive fun for wee ones and not-so-wee ones alike.
0previous images
-25more images


text:
Trial record 1 of 14 for: "Adrenal cancer"
Previous Study | Return to List | Next Study
A Pilot Study of F-18 Paclitaxel (FPAC) PET for Evaluating Drug Delivery of Solid Tumors in Breast, Lung, Renal, and Adrenal Cancers
This study has been terminated.
National Cancer Institute (NCI)
Information provided by (Responsible Party):
National Institutes of Health Clinical Center (CC) ( National Cancer Institute (NCI) )
ClinicalTrials.gov Identifier:
First received: March 12, 2010
Last updated: June 30, 2017
Last verified: May 11, 2016
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Show Detailed Description
- Paclitaxel is a chemotherapy drug that is commonly used to treat different types of cancers. However, cancer tumors can become resistant to paclitaxel, and as a result they will fail to accumulate sufficient concentrations of paclitaxel to kill the cancer cells. Researchers are interested in studying whether tumors have become resistant to paclitaxel, but to do so it must be possible to see how much paclitaxel is absorbed by the tumor cells.
- 18F-Fluoropaclitaxel (FPAC) is a form of paclitaxel that has been modified to be slightly radioactive in order to show up on positron emission tomography (PET) scans. By injecting a very small amount (much less that that used to treat tumors) of the radiolabeled drug into the body, researchers hope to use PET scans to evaluate the amount of the drug absorbed by solid tumors. Because FPAC is best used to study tumors located above the diaphragm, all subjects in the study will have tumors near or above the diaphragm.
- To determine the safety and effectiveness of FPAC as a radiological evaluation chemical.
- Individuals at least 18 years of age who have been diagnosed with breast, adrenal, renal, or lung cancer and have a tumor located someone in the body at least 1 centimeter above the diaphragm.
- Participants will be screened with a physical exam, blood tests, and imaging studies as directed by the study researchers.
- Participants will receive a single dose of FPAC, followed by a series of PET scans. Regular scans will be performed for 3 hours after the dose of FPAC.
- Participants will also have a single dose of a more conventional radiotracer, followed by a series of PET scans. The results of the two sets of scans will be compared with information from previous imaging studies of participants' tumors....
|Breast Cancer Lung Cancer Renal Cancer Adrenal Cancer
|Drug: FPAC
|Early Phase 1
|Study Type:
|Study Design:
|Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Diagnostic
|Official Title:
|A Pilot Study of F-18 Paclitaxel (FPAC) PET for Evaluating Drug Delivery of Solid Tumors in Breast, Lung, Renal, and Adrenal Cancers
Resource links provided by NLM:
Genetics Home Reference related topics: breast cancer lung cancerU.S. FDA Resources
Further study details as provided by National Institutes of Health Clinical Center (CC) ( National Cancer Institute (NCI) ):
Primary Outcome Measures:
- Uptake of FPAC in tumors [ Time Frame: 1 hour post injection of FPAC ]
- Safety of FPAC [ Time Frame: 1-3 days after FPAC injection ]
|Study Start Date:
|March 9, 2010
|Study Completion Date:
|May 11, 2016
|Primary Completion Date:
|August 20, 2014 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: 1
subjects with tumor types typically treatedwith taxanes
Drug: FPAC
Each subject will be administered 7 mCi of FPAC,over 10-20 seconds, followed by saline flush.
Experimental: 2
subjects with tumor types typically treatedwith taxanes
Drug: FPAC
Each subject will be administered 7 mCi of FPAC,over 10-20 seconds, followed by saline flush.
Show Detailed Description
|Ages Eligible for Study:
|18 Years to 100 Years (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
- Subjects must have a history of histologically or cytologically confirmed breast, lung, adrenal or renal cancer with a tumor above the diaphragm greater than or equal to 1 cm
- Subjects must be 18 years or older for inclusion in this study.
- Subjects must sign a written informed consent document and in accordance with institutional guidelines.
- If female, the subject must be postmenopausal for a minimum of two years, be surgically sterile, or have a negative pregnancy test within the 24 hours prior to tracer injection
- There are no study related limitations regarding previous radiation or chemotherapy.
- Subjects must have an ECOG performance status less than or equal to 2 (Karnofsky greater than or equal to 60%)
- Subjects must have normal organ and marrow function as defined below:
- leukocytes greater than or equal to 3,000/mcL
- absolute neutrophil count greater than or equal to 1,500/mcL
- platelets greater than or equal to 100,000/mcL
- total bilirubin within less than or equal to 2.5 times institutional limits OR < 3.0 mg/dl in patients with Gilbert s syndrome
- AST(SGOT)/ALT(SGPT) less than or equal to 2.5 times the institutional upper limit of normal (<5 times the ULN for patients with known hepatic metastases)
- When applicable, a documented history of prior chemotherapy and radiation therapy and responses to those treatments must be available.
- Subjects may not receive any other investigational agents 24 hours prior to or following FPAC injection
- Subjects must NOT receive radiation therapy to the target lesion less than or equal to 8 weeks prior to FPAC injection
- Subjects must NOT have had surgery near the target lesion less than or equal to 4 weeks prior to FPAC injection
- Subjects with a history of allergic reactions attributed to compounds of similar chemical or biologic composition to F-18 fluoropaclitaxel (i.e. Taxol)
- Subjects with severe claustrophobia (not relieved by oral anxiolytics) or other condition that would make them unable to lie still for the duration of the study
- Subjects with uncontrolled intercurrent illness or psychiatric illness/social situations that would limit compliance with study requirements
- Subjects who are pregnant or lactating or who suspect they might be pregnant. Because there is an unknown but potential risk for adverse events in nursing infants secondary to treatment of the mother with FPAC, breastfeeding should be discontinued if the mother receives FPAC.
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01086696
Please refer to this study by its ClinicalTrials.gov identifier: NCT01086696
|United States, Maryland
|National Institutes of Health Clinical Center, 9000 Rockville Pike
|Bethesda, Maryland, United States, 20892
Sponsors and Collaborators
National Cancer Institute (NCI)
|Principal Investigator:
|Karen A Kurdziel, M.D.
|National Cancer Institute (NCI)
More Information
Keywords provided by National Institutes of Health Clinical Center (CC) ( National Cancer Institute (NCI) ):
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on September 21, 2017
Hsueh WA, Kesner AL, Gangloff A, Pegram MD, Beryt M, Czernin J, Phelps ME, Silverman DH. Predicting chemotherapy response to paclitaxel with 18F-Fluoropaclitaxel and PET. J Nucl Med. 2006 Dec;47(12):1995-9.
Logan J. Graphical analysis of PET data applied to reversible and irreversible tracers. Nucl Med Biol. 2000 Oct;27(7):661-70.
|Responsible Party:
|National Cancer Institute (NCI)
|ClinicalTrials.gov Identifier:
|NCT01086696 History of Changes
|Other Study ID Numbers:
|Study First Received:
|March 12, 2010
|Last Updated:
|June 30, 2017
Keywords provided by National Institutes of Health Clinical Center (CC) ( National Cancer Institute (NCI) ):
PET Imaging
F-18 Paclitaxel (FPAC)
Breast Cancer
Lung Cancer
Renal and Adrenal Cancers
Kidney Cancer
Adrenal Cancer
Additional relevant MeSH terms:
Kidney Neoplasms
Carcinoma, Renal Cell
Adrenal Gland Neoplasms
Urologic Neoplasms
Urogenital Neoplasms
Neoplasms by Site
Kidney Diseases
Urologic Diseases
Neoplasms, Glandular and Epithelial
Neoplasms by Histologic Type
Endocrine Gland Neoplasms
Adrenal Gland Diseases
Endocrine System Diseases
Albumin-Bound Paclitaxel
Epinephryl borate
Antineoplastic Agents, Phytogenic
Antineoplastic Agents
Tubulin Modulators
Antimitotic Agents
Mitosis Modulators
Molecular Mechanisms of Pharmacological Action
Adrenergic alpha-Agonists
Adrenergic Agonists
Adrenergic Agents
ClinicalTrials.gov processed this record on September 21, 2017


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KEEPERS at Dudley Zoo are inviting children to help care for some of the site's wild birds this half term.
Young visitors can decorate a nest box in the Discovery Centre, which staff will fix to trees around the zoo's 40-acre wooded hillside to enhance the population of native birds.
Birds section leader, Kellie Piper, said: "We've got hundreds of small wild birds around the zoo site including chaffinches, robins, blue tits, long tail tits and nuthatches, which all need to find places to nest in the coming weeks.
"With many of their natural nesting sites fast disappearing it is vital we provide suitable boxes that are safe and warm for them to start laying their eggs in."
The free activity coincides with National Nest Box Week, which aims to encourage bird lovers to add nest boxes to their gardens to help breeding birds.
Kellie added: "We hope many of our young visitors will help us decorate the boxes and then hopefully spot their box being used in a few months time."


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A Study to Measure the Effectiveness of an Intervention Package Aiming to Decrease Perinatal Mortality and Increase Institution-based Obstetric Care Among Indigenous Populations in Guatemala
Recruitment status was: Recruiting
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- No Study Results Posted
- Disclaimer
- How to Read a Study Record
A matched pair cluster-randomized trial of this intervention package will be conducted in four rural and indigenous districts (Huehuetenango, Quiche, Alta Verapaz and San Marcos) of the Republic of Guatemala, using the health clinic as the unit of randomization. No external intervention is planned for control facilities, although enhanced monitoring, surveillance and data collection will occur throughout the study in all facilities in the four districts.
The package includes 3 interventions: 1) To train health care professionals in emergency obstetric and perinatal care using an innovative high-fidelity, low-tech, in situ, multidisciplinary simulation training curriculum (PRONTO); 2) To design and implement a social marketing strategy that promotes institution-based delivery; and 3) To integrate the role of obstetric nurse and professional midwife in intervention communities to act as liaisons between traditional birth attendants (TBA) and public health units. A fourth, cross-cutting component involves ongoing analysis, monitoring, surveillance and evaluation to strengthen information systems and monitor perinatal outcomes throughout the two years of the study.
|¨Maternal Morbidity¨ ¨Perinatal Mortality¨
|Other: package of 3 interventions
|Study Type:
|Study Design:
|Intervention Model: Single Group Assignment
Masking: Double (Investigator, Outcomes Assessor)
Primary Purpose: Prevention
|Official Title:
|A Matched Pair Cluster-randomized Implementation Study to Measure the Effectiveness of an Intervention Package Aiming to Decrease Perinatal Mortality and Increase Institution-based Obstetric Care Among Indigenous Populations in Guatemala
- increase the proportion of institutional deliveries in intervention vs. control clusters [ Time Frame: Up to 15 months ]
- Decrease perinatal death rate in intervention vs. control clinics [ Time Frame: Up to 15 months ]
|Estimated Enrollment:
|Study Start Date:
|July 2012
|Estimated Study Completion Date:
|December 2013
|Estimated Primary Completion Date:
|October 2013 (Final data collection date for primary outcome measure)
|Assigned Interventions
|Experimental: package
Other: package of 3 interventions
Emergency Obstetric Care training, social marketing approach and link TBS with public sector services
Detailed Description:
Overall goal
To evaluate the impact of a package of three interventions aiming to increase institution-based delivery and improve emergency obstetric and neonatal care on perinatal mortality, in the four districts with the highest maternal mortality ratios in Guatemala.
Specific objectives
- Measure the impact of this intervention package on perinatal mortality rates.
- Measure the impact of this intervention package on the proportion of institution-based delivery among study facilities.
- Evaluate the processes and success of implementing this combined package of interventions by analyzing process indicators related to the intervention element designed to improve emergency obstetric and neonatal care (PRONTO: emergency obstetric and perinatal training program).
Primary outcome of interest:
- Increase in the proportion of institutional deliveries in intervention vs. control clusters.
- Decrease perinatal death rate in intervention vrs control clinics
|Ages Eligible for Study:
|10 Years to 49 Years (Child, Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- rural women
- indigenous
- poor
- Facilities at rural area
- Clinic attending vaginal deliveries
Exclusion Criteria:
- Facilities considered too close geographically to risk contamination of intervention to control facilities
- Clinics visits by pregnant women who present to intervention or control clinics for reasons other that an obstetric event
- Clinic or hospital visits by women who present to intervention or control clinics in the post partum period
Please refer to this study by its ClinicalTrials.gov identifier: NCT01653626
|Health Centers for vaginal deliveries (CAP)
|Departamento de San Marcos, Guatemala
|Contact: Edgar E. Kestler, MD (502) 22301494 email@example.com
|Sub-Investigator: Dilys Walker, MD
|Principal Investigator:
|Edgar E Kestler, MD
|Principal Investigator:
|Edgar E. Kestler, MD
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
|Responsible Party:
|Edgar Kestler, Director, World Health Organization
|ClinicalTrials.gov Identifier:
|NCT01653626 History of Changes
|Other Study ID Numbers:
|Study First Received:
|July 25, 2012
|Last Updated:
|July 30, 2012
Additional relevant MeSH terms:
Perinatal Death
Pregnancy Complications
Pathologic Processes
ClinicalTrials.gov processed this record on September 21, 2017


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Ghita is Prepared for Glory 9 NY
The sport of Kickboxing is one that is still growing and evolving every day, even if it has been around for quite a while now. If you need proof of that, look no further than Daniel Ghita, who fights this weekend at Glory 9 New York against Brice Guidon. Ghita, a Romanian fighter, began as a bruiser whose kicks were his best weapon. Since then Ghita has evolved not only as a fighter but as a sportsman as well. He shows a media savvy and professional attitude at all times.
As always, we caught up with Daniel Ghita before his next fight and asked him some questions, because, c'mon, who doesn't like hearing from Daniel Ghita? He's heading into his first fight on American soil looking to pick up a big win and impress American fans and we think that we will be in for one helluva fight.
LK: Brice Guidon is a tough, underrated fighter who has had some strong showings over the past few years, what do you see as Guidon's biggest strength that you have to look out for?
DG: I do not prefer to talk about the skills of other fighters. He is a good strong fighter not to underestimate. I will have to look and be very aware, he has a different style of fighting.
LK: Both of you guys are coming off of back-to-back losses, which has been known to push fighters harder than before. What do you have to do against Guidon to make sure that you pick up the win?
DG: Simply just get in the ring and do your job. Honestly we all have ups and downs. I say many times, we are not machines, we are human and can make mistakes. In top sport every simple mistake can cost you the match. You can lose and you can win. I do not feel pushed after I lose a match. I do a "total recall,"l translated, I start again from zero . I leave the past in the past and think just what I can do in the present. I know, people get disappointed I do not talk in public about my colleagues.
LK: Did you get injured after that sweep from Saki in the last fight? It seemed like something was off with you after that sweep. Do you feel like it changed the landscape of the fight?
DG: I lost my balance for a second and I felled down on my hand and hurt myself. It was terrible pain. People were talking that I broke my hand! Believe me next day I was sitting with Saki on the table talking very friendly. We both were injured! It was a fight like other fights. I will not say that I had a bad day. I had a difficult period before this match which had a bad influence on me. It is private and do not want to discuss it in public. Some things in our life we can not control, even a top sportsman. On every interview people are asking me just two questions: Saki and Semmy! Honestly it makes me really laugh.
LK: What do you consider you need to do to get back on top of the Heavyweight division right now?
DG: I think I'm in the top ranking 3? What is top? Hahaha I just continue what I started 19 years before, this sport I do is my passion. This sport made made me what I'm today.
LK: Looking beyond the fight with Guidon, who would you like to fight next?
DG: Every fighter at Glory is for welcome! No preference! Ok, ok, maybe Pierre Andurand? Hahahaha He is incredible guy, very good with his fighters and saw that he is fighting too.
LK: This is your first fight in the United States, are you looking forward to fighting in the United States? Have you ever visited here?
DG: NYC was a dream of mine ! I will visit for the first time United States . I'm very happy I have this opportunity now to fight for my fans un US and I really look forward and can't wait to fight in United States.
LK: Badr Hari has fallen on some rough times, for a while one of the biggest fights to make in Heavyweight Kickboxing was Ghita vs. Hari, would you still want to fight Badr at some point?
DG: This question I get every time I gave an interview. I will say: no comment! Let's live and see what the life brings.
LK: Are you going to do anything fun while in New York? Go sightseeing, take in a show or anything else? Or will it be strictly business for you?
DG: Only business and something nice too. I can not say it now. You will read about it!
LK: You did extremely well in last year's Glory Grand Slam tournament, are you prepared for another one this year?
DG: Yes, be sure of that! I will to do it better this year.
CommentsPost new comment
I hope he finds his Shape again cus he was a killer !!
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SANTA CLARA -- Colin Kaepernick rifled a 20-yard touchdown pass that Michael Crabtree caught in blazing stride early in Tuesday's practice. Four passes later, Kaepernick lobbed a 35-yard touchdown pass to an uncovered Crabtree.
Yes, the Kaepernick-to-Crabtree connection lives, never mind that the 49ers' past two seasons have ended with their failed hookups in the end zone.
"He's a step or two quicker," Kaepernick said. "He has burst out of his routes. He has burst when he catches balls."
Crabtree might again emerge as Kaepernick's favorite target. This camp, however, Kaepernick finally has other enticing options.
"It makes it a lot easier when you have four 1,000-yard receivers out there," Kaepernick said, referring to Crabtree, Anquan Boldin and newcomers Stevie Johnson and Brandon Lloyd. "It's something we're excited as quarterbacks, as an offense and as a team."
Tuesday's team drills also marked speedy rookie Bruce Ellington's practice debut after an ankle sprain, and Kaepernick said he "doesn't play like a rookie." If the 49ers keep six wideouts, Quinton Patton would be the favorite to round out the corps.
That boost of talent is critical to improve upon last season's 30th-ranked passing attack. Kaepernick not only likes the more weapons he sees, he's become more vocal in various ways as he enters his second full season as a starter.
"Sometimes he'll speak up in meetings and give his expectations for landmarks and locations of the ball," Lloyd said. "He'll have the floor in the meeting and he'll be able to discuss what he sees and what he expects out of the plays."
Kaepernick attributes that in part to his self-confidence, as well as the need to catch the new wideouts up to speed.
"We want to make sure Stevie, Brandon and Ellington are on the same page with what we have been doing," Kaepernick said. "At the same time I want to make sure everyone hears what I'm saying, so they see things from my perspective, and I hear things from their perspective on how they want to run routes."
From Kaepernick's perspective, Crabtree is fully recovered from his May 2013 Achilles tear. Just about the only thing Crabtree hasn't done this camp is acquiesce to the media's interview requests.
"I'm excited to see what he can do now that he's 100 percent," Kaepernick said of Crabtree.
Lloyd is excited about having emerged from a year hiatus to resume a career that began with the 49ers from 2003-05.
"It's been good picking it up, but there are a lot nuances and formations that are the curveballs within the offense," Lloyd said. "There's a lot of details. It hasn't been easy but I've been enjoying the process."
Both Lloyd and Kaepernick insist this revamped receiving corps offers various looks, even if their dimensions are somewhat similar -- Lloyd is 6-foot, 200 pounds; Crabtree 6-1, 214; Boldin 6-1, 220; Johnson 6-2, 207.
"There's a lot of diversity in how each one of us gets open and how we approach route running and catching the ball," Lloyd said.
Added Kaepernick: "It's good to have a variety of receivers with different moves. That makes it harder on defenses."
For more on the 49ers, see Cam Inman's Hot Read blog at blogs.mercurynews.com/49ers. Follow him on Twitter at twitter.com/CamInman.


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Wednesday, January 9
Cosentino: The Grand Illusionist, Channel Seven, 7.30pm
IF YOU missed Cosentino's turn on Australia's Got Talent last year, here's your chance to see the runner-up in action. Filmed during his sell-out show at the Regent Theatre and on the street amid unsuspecting shoppers, ''Australia's No.1 illusionist'' here showcases his Michael Jackson-style dance moves, a dandy aesthetic that borrows from Russell Brand and Captain Jack Sparrow, and a few good tricks. He's an engaging enough performer, but magic loses its immediacy and ability to impress when viewed through a TV screen. The body being sawn in half thing is a bit old hat but it's hard not to marvel, from a distance, at his telekinesis and Houdini-esque escape routine. We're guessing you'd have to check out Cosentino live for a truly magical experience.
My Big Fat Operation, ABC2, 8.40pm
OBESITY in Britain has become a problem of epidemic proportions. This series traces the journeys of 12 morbidly obese Britons who undergo bariatric surgery to help them win the weight war. Tonight we meet Shanel, a 22-year-old who weighs twice what she should for her height. She eats her lunch out the back of the cafe she works in, ashamed to let others see her eat. Matt is a 39-year-old who, at his heaviest, weighed 279 kilograms. In a deeply depressing sequence, he reveals - to the tune of violins, while patting his cat - that he lives with his mother, is too fat to work and that most of his friends are online. The surgeries are drastic but there's no doubting they come out the other end smaller, happier people. More on the psychology of obesity would have made for a more enlightening show.
Grimm, Channel Seven, 8.30pm
ANOTHER double serve of the police procedural infused with the supernatural tonight, with the first episode proving it's going to be tricky for Portland homicide detective Nick Burkhardt to continue to keep his secret - he sees mythological creatures - from his fiancee, Juliette. Burkhardt is descended from a long line of criminal profilers that began with the Brothers Grimm, see, and tonight must do battle with a bunch of fire-breathing beasts. The daughter of one works as a fire dancer in a racy club and, taking a liking to Burkhardt, sets out to get between him and his gal. How Juliette has failed to smell a big abnormal rat at this stage of this series remains a mystery. Good escapism is not about being plausible though, is it?
Russell Brand: From Addiction to Recovery, ABC2, 9.30pm
ESSENTIALLY a TV adaptation of his 2007 memoir, My Booky Wook, Brand says this documentary was inspired by the passing of Amy Winehouse at 27, the same age Brand was when he recovered from his drug and alcohol addiction. Brand meets Winehouse's father, Mitch, visits friends, agents and counsellors who knew Brand back when, and talks to addicts in prisons, rehab programs and on the streets. Brand is adamant (as presented to a British home affairs committee) that methadone treatment is simply transferring users from one substance dependency to another (he advocates the abstinence method), but doesn't speak to any of the many former addicts who have rebuilt their lives, helped by methadone.
Who Do You Think You Are?: Gregg Wallace, BBC Knowledge, 8.30pm
MASTERCHEF'S Gregg Wallace begins his journey with what seems like a mean and unnecessary swipe at one of his three former wives. He might not have intended it that way, but it makes him come off poorly and it undermines the whole episode. It's hard to get emotionally involved in a celebrity's journey if you suspect that they might actually be a bit of an arse. In any event, Wallace begins by looking up the great-grandfather who, family legend has it, deserted the Royal Navy around the turn of the century and abandoned his young family to run away to Australia. The truth turns out to be rather different but no less interesting. As is so often the case, Wallace's family story turns out to be dotted with tragedies. Who Do You Think You Are? remains a fine and fascinating series, with this season's subjects including Annie Lennox, Patrick Stewart and Celia Imrie. Fans of genealogy TV should also check out Coming Home (Thursday, Bio, 9pm), in which British celebs trace their Welsh roots.
Say Yes to the Dress, Discovery Home & Health, 7.30pm
IT'S AN ostensibly exciting time at the New York bridal salon - TV presenter Kelly Ripa (Live! With Regis and Kelly) is going to try her hand at selling wedding dresses. Tonight's brides are a study in contrasts. One momentarily feels bad that her father is selling his motorbike to pay for her $11,000 dress; another has no compunction about making her fiancee pay $50,000 for two of them.
Banged Up Abroad, Nat Geo Adventure, 7.30pm
American Gerald Amster tells of how he escaped from a Soviet prison after being caught smuggling heroin in 1976.
Mr D, Comedy, 9pm
Canadian comic Gerry Dee stars in a sitcom based on his own experience as a schoolteacher.
Never Been Kissed (1999), Channel Ten, 8.30pm
RAJA Gosnell's deconstructed teen movie in which a 25-year-old journalist, Josie Geller (Drew Barrymore), pretends to be 17 and returns to her old high school. She's supposed to be doing a student expose but no one - including a bewildered audience - knows what her article is supposed to be about.
That's because, in modern America, the only story that really interests people is the self-obsessed journey to self-realisation.
The most used word in this film is ''popular''.
The myopic dream is to be the most popular person in class, because that could help make you prom queen or king, and one day - who knows? - US president.
Though easy to ridicule and often hard to watch, the film has compensatory pleasures, especially Barrymore, who works overtime to generate genuine fun and warmth.
However, whether you love it or not will come down to the ending, a fantasy encounter in front of a packed crowd and the television cameras of America. Personal stories in the US have a tendency to be lived out in public.
Full Confession (1939), ABC1, 4.15am (Friday)
BORN in Marrickville in 1904, Australia's John Farrow sailed around the world, ending up in the US where he found work as a scriptwriter. It would ultimately lead to his winning a best screenplay Academy Award for Around the World in 80 Days in 1956.
Twenty years earlier, Farrow was fired from his first feature as director, Tarzan Escapes, because it was too free-minded. But at least he met and married its lead actress, Maureen O'Sullivan. In 1939 he directed Full Confession, the compelling story of Michael O'Keefe (Barry Fitzgerald), wrongly sentenced to the electric chair. Father Loma (Joseph Calleia) has heard the confession of the real killer but cannot use the knowledge to save an innocent man.
Farrow wrings maximum tension from the priest's struggle of conscience, and his attempts to get the murderer to publicly admit his guilt. Farrow was a deeply conservative Catholic, so not surprisingly he supported the seal's inviolability. But in Full Confession he argues cogently for a pragmatic and humane approach to worldly affairs. This film is even more relevant today than when it was made.
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A man from a San Diego-based sailing crew died and five people were injured when the surf tore their sailboat apart off San Clemente Island during a race late Friday.
A San Diego-based Coast Guard air team rescued the crew of the 30-foot sailboat Uncontrollable Urge after the disabled vessel drifted into the surf and broke apart near the island, which lies 70 miles northwest of San Diego.
By the time the rescue helicopter arrived, 36-year-old Craig Thomas Williams of Serra Mesa had died. Williams was a member of the Silver Gate Yacht Club located on Shelter Island.
He was part of a crew competing in the Islands Race, co-hosted by the Newport Harbor Yacht Club and San Diego Yacht Club. The 139-nautical mile course starts in Newport Harbor, rounds the Catalina and San Clemente islands, and ends in San Diego.
There were 41 sailboats registered for the race as of Thursday, according to the race website, including Uncontrollable Urge, a carbon-fiber Columbia 32 whose owner, James Gilmore, is also a member at Silver Gate Yacht Club.
It was Uncontrollable Urge's first race, according to Gilmore's Twitter account.
"Gonna see what this boat can do!" he tweeted Friday morning.
Williams, an architect, is survived by his wife, Kjersti, who is pregnant, and 2-year-old daughter Claire, a family member said.
Donations to assist the family may be made through the website http://www.youcaring.com/memorial-fundraiser/Honor-the-memory-of-Craig-Williams-husband-father-and-friend/46040.
"Silver Gate Yacht Club is very sad to acknowledge the loss of one of our members, as well as the loss of a member's boat," stated a news release from the club. "This is a tragedy for the families and our club is in mourning for the loss of life."
The crew issued a mayday call around 9:30 p.m. after the boat's rudder failed during the race, but initially declined help from both the Coast Guard and other racers, authorities said.
"When your rudder fails, you lose steering control of the boat, but there wasn't an immediate emergency as far as they were concerned," explained San Diego Yacht Club Commodore Chuck Hope.
Instead, the crew called on a commercial salvage company for help, but the company was unable to launch in the weather conditions, which included 8-foot swells and 10-knot winds. A small-craft advisory was in effect.
Hope said Uncontrollable Urge met all the standard safety requirements for an offshore race. Weather conditions were bad, he added, but not abnormally so.
"This was an experienced crew, and it's not the only boat that suffered damage in the race," he said. "Two other crews abandoned the race for equipment failures. There were storm conditions, but not anything unusual for an offshore. It's not so much that it was a freak storm. It was bad weather."
He said the crew failed in an attempt to deploy a life raft, which the offshore race requires sailboats to have on board. Coast Guard officials said the Uncontrollable Urge crew also tried to anchor their vessel just after 11 p.m., but the anchor did not catch and the sailboat drifted closer to the island. It was eventually broken apart by the surf, forcing the crew to abandon ship off the northwestern shore of the island.
The Coast Guard launched an MH-60 Jayhawk helicopter crew and deployed Coast Guard Cutter Edisto to the scene.
The helicopter crew lifted the six sailors and brought them to San Diego, where the five survivors received medical attention and were taken to the hospital.
San Clemente Island is the southernmost of eight California Channel Islands and has been operated by various naval commands since 1934.
Friday's wreck is the second fatal sailboat crash near San Diego in less than a year. Four were killed off Mexico's Coronado Islands last April during the Newport to Ensenada Yacht Race.


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Twelve named Michigan Dairy Ambassadors
Twelve dairy youth kicked off their year of dairy promotion and outreach as Michigan dairy ambassadors during the Great Lakes Regional Dairy Conference (GLRDC) in Mt. Pleasant, Mich. on Friday, Feb. 7.
Three high school junior dairy ambassadors – Mason Horning of Manchester, Evelyn Okkema of Blanchard and Libby Venema of Deford – and nine college senior dairy ambassadors – Megan Bush of Swartz Creek, Natalie Horning of Manchester, Kayle Jakus of St. Johns, Quinn Kolar of Troy, Jennie Lubbers of Lake Odessa, Laura Lubeski of Bad Axe, Allison Pung of Portland, Kailey Sweers of Dansville and Heather Van Lieu of Reading – spent the day training for their upcoming role as dairy advocates.
Ambassadors participated in educational sessions covering topics ranging from media relations to social media while showcasing their passion for the dairy industry to a panel of judges. Throughout the year, the 12 reigning dairy ambassadors will be afforded further training as well as opportunities to represent the dairy industry during promotion and outreach events.
In addition to training sessions, ambassadors competed for scholarships and the titles of junior and senior Michigan dairy ambassador representative.
Mason Horning, a sophomore at Manchester High School, was named the junior ambassador representative and was awarded a $1,000 scholarship. Megan Bush, a junior at Michigan State University, and Kailey Sweers, a sophomore at Hope College, were announced as the senior ambassador representatives, each receiving a $1,500 scholarship.
To learn more about the Michigan Dairy Ambassador Scholarship and Leadership Program, visit www.glrdc.msu.edu.
Michigan: Dairy energy conversation workshops
Michigan State University (MSU) Extension, Consumers Energy, and DTE Energy are sponsoring a series of workshops across Michigan designed to help dairy farmers learn how they can reduce their energy expenses and take advantage of power company rebates and federal dollars to implement recommended energy conservation practices.
MSU studies have shown, on average, a 46% reduction in energy expenses when recommended energy conservation practices have been implemented.
Attendees will hear from specialists from MSU and MSU Extension, as well as power company representatives, with agricultural energy conservation expertise. Farmers with practical experience in implementing energy conservation practices that saved them money will share their experiences. Attendees will receive information on applying for power company rebates and federal grant dollars to implement energy conservation practices.
The program will run from 10 a.m. to 2 p.m. at each site and will include lunch. Lunch at the Holland and St. Johns sites is sponsored by Consumers Energy. Lunch at the Cass City site is sponsored by DTE Energy. Dates and locations include:
• March 11: MSU Bioeconomy Institute, 242 Howard Street, Holland, MI 49424
• March 12: DTE Energy North Area Energy Center, 4100 Doerr Road, Cass City, MI 48726
• March 13: Smith Hall, 800 Sickles St., St. Johns, MI 48879
There is a $10 registration fee to participate in this program. The registration fee covers handouts, room rental fees, and refreshments.
Ohio State survey to explore custom work rates
Agricultural economists from Ohio State University's College of Food, Agricultural, and Environmental Sciences want to know how much Ohio growers engage farm workers and machinery operators as part of the college's Ohio Farm Custom Rate Survey.
The survey is conducted biannually by Barry Ward, production business management leader for Ohio State University Extension, as a means of gauging farm work completed by others, which is often referred to as "custom farm work" or "custom work," he said.
The survey is targeted at both those who hired custom farm work and those who performed the work, Ward said.
The data gathered through the custom rate survey is published by OSU Extension and used by Extension professionals in their work with Ohio communities, Ward said. OSU Extension is the outreach arm of the college.
The survey has proved useful over the years as custom farming providers and customers often negotiate an agreeable custom farming rate by utilizing OSU Extension survey results, he said.
The survey can be completed online at: http://aede.osu.edu/customrate2014. The deadline is March 7.
PDPW Business Conference sets specialty sessions
The 2014 PDPW Business Conference will offer 16 specialty sessions on a wide range of topics faced by dairy producers, no matter what size, style of type of dairy farm they run. The conference will be held March 12-13 at the Alliant Energy Center in Madison, Wis., under the theme, "Exceeding Excellence."
Specialty session topics and speakers include:
• "21st Century Dairying: How to Select and Maximize Robotic Milking Systems," led by Jim Salfer of the University of Minnesota Extension will share results from recent research on robotic milking on 52 dairies in Wisconsin and Minnesota. Two producer panelists will address common questions based on their experience with robotic milking: Chad Kieffer of Utica, Minn., and Jake Peissig of Dorchester, Wis.
• "Smooth Moves: Dotting I's and Crossing T's When Modernizing or Expanding" will explore the rules and regulations as well as the people dairy farmers need to engage as they begin an expansion or modernization project, including realistic timelines to work through the permitting process. Leading this session is the former director of the University of Wisconsin Discovery Farms Program, Dennis Frame, and Agricultural Attorney Jordan Lamb.
• "The Total Package: Creating Employee Compensation that Works" will show that dairy producers can create a plan to attract and retain good people. This session, led by "Dairy Coach" Tom Wall, will focus on how to design and implement a compensation strategy that reduces employee turnover and rewards performance. The content will be applicable to any size dairy, whether hiring full- or part-time workers.
• "Meet the Demands of Others with Servant Leadership Style" will examine how producers can rise to meet the expectations of consumers, more stringent regulations, and increased liability -- all through a "servant leadership" style. Viterbo University's Tom Thibodeau will show attendees how this style of leadership is a perfect match for agricultural professions.
• "Odor Management: Your Answer to Those Who Raise a Stink" will examine the science of odor generation, how it travels, and how it is perceived by others. Dr. Robert Mikesell, who has evaluated more than 300 sites for new livestock facilities, will present dairy odor reduction strategies and abatement methods, explore current laws in place, and discuss the legal and social framework for compliance.
• In a Jeopardy® game show-style session, Dr. Richard Wallace and Dr. David Rhoda will present "Milk and Meat Expectations: Know the Answers Before Final Jeopardy." Audience members will be quizzed on how well they recognize the risk of residues on a dairy and current regulation involving dairy producers and veterinarians. Emphasis will be placed on ways the industry can work together to improve protocol development, treatment and culling decisions and provide quality meat and milk for consumers.
• "Corn ShredlageTM: Hype, Hip or the Next Biggest Thing?" will provide the skinny on a relatively new type of corn silage. In this session, Dr. Randy Shaver will review the research. Dairy producer Aaron Kutz along with Shredlage inventor and technical director Roger Olson will share experiences with this new process and the end results.
• Dr. Rebecca Brotzman will lead "Home Sweet Home for Heifers and Post-weaned Calves," exploring the important components of heifer housing for the transitioning, post-weaned calf through springing heifer. Heavy on practical considerations and real-life examples, this session will walk you through decisions such as facility size, feed and resting space, ventilation method, and grouping strategy.
• In the session, "There's Something About You That Makes Me Want to…" Trainer Tom Thibodeau will explore those certain qualities that inspire and motivate others to follow your lead and perform at a high level. This session will use years of research to define the characteristics of a good leader, and help dairy producers create a plan to develop those characteristics within themselves.
• "How Now, Down Cow?" will review basic principles to improve a down cow's outcome and reduce any suffering the down cow experiences. Robert Leder, DVM, will teach producers how to develop protocols for handling down cows that improve the outcome for everyone involved – cow, farm employees and farm management.
• Properly ventilated barns are essential for cow comfort, cow health and overall milk production. In "The Air of Profitability," Professor Brian J. Holmes will present the freshest research on air quality, and then moderate a panel discussion featuring the facility experiences of dairy producers Eric Hillan of Ladysmith, Wis., Paul Fetzer of Elmwood, Wis., and Roger Peterson of River Falls, Wis.
• "Freshen Up Your Fresh Pens" will offer the latest research on how dairies can maximize the use of fresh pens and turn red ink to black. Dr. Garrett Oetzel, DVM, will review approaches to examining individual cows, disease diagnostic criteria, disease treatment protocols, involvement of veterinarians in fresh pen management, budgets for various fresh pen strategies, the legal use of pharmaceuticals, and data management tools to monitor fresh cow health.
• In "Finding and Targeting High Risk Fresh Cows," Dr. Garrett Oetzel, DVM, will provide the latest research findings that are helping us identify high risk fresh cows as soon as they leave the maternity pen and use interventions that improve their health and productivity. Partial budgets that demonstrate the economic value of targeted early detection and treatment programs for hypocalcemia and ketosis will be presented.
• "From Family Farm to Economic Engine" will help farm families look beyond survival to real entrepreneurship. Mike McGrann will outline the mindset required to become an Enterprising Family, including how to identify entrepreneurial opportunities, determine the feasibility of opportunities, understand your fit within a "value chain," and assess the entrepreneurial capabilities in your family. Dairy Producer Tim Kurtz of Elverson, Penn., will share his family's transformation story.
• "Managing Conflict and Building Relationship Capital Between Generations" will offer the keys to long-term success in family enterprises. Session leader Mike McGrann will provide a framework for managing conflict in families – including 10 specific skills and tools that are critical to effective communication.
• "Half-full or Half-empty? Measuring and Monitoring Feed Cost, Capacity and Consumption" will explore the various options and opportunities to reduce feed expenses on and off the farm depending on the feed and storage systems a producer chooses. Ken Griswold, Director for Ruminant Technical Services for Kemin Animal Nutrition & Health, will explain how each system comes with its own costs and management responsibilities, so producers can choose what is right for their farm.
In addition to these specialty sessions, five keynote speakers, an expanded Hall of Ideas and Large Equipment Show, FreshPicks presentation stages and time for networking with other dairy producers from around the globe are all part of the 2014 PDPW Business Conference experience. To receive a complete conference flyer or to register, visit www.pdpw.org, or call PDPW at 800-947-7379.
Dairy 30x20 Processor grant applications due Feb. 21
Dairy processors need to apply by February 21 to take advantage of the Grow Wisconsin Dairy 30x20 Processor Grant. This new grant from the Department of Agriculture, Trade and Consumer Protection (DATCP) can be used for operational changes that will improve production and profitability.
Grants will be given up to $50,000 per proposal. The funds can be used to develop a new innovation or address an existing concern in the processing facility.
Applicants must operate or plan to operate a licensed dairy processing plant in Wisconsin. Applicants must also provide at least 20 percent of the total grant award as a matching contribution.
The Grow Wisconsin Dairy 30x20 Initiative offers grants to farmers and processors as part of its overall goal to ensure the long-term vitality of the state's dairy industry and meet the growing demand of the marketplace. A group of dairy stakeholders met with DATCP staff last October to develop this new grant and discuss industry priorities.
Applicants are encouraged to create proposals that encourage collaboration or could generate insights that would benefit the entire industry. Examples of projects could be dairy plant modernization, expansion, food safety assistance, staff training or professional consultation services to develop new processes.
The application is available at GrowWisconsinDairy.wi.gov. For more information, call 855-WI DAIRY (855-943-2479) or email email@example.com. The toll-free number is also available throughout the year to connect farmers and processors with available resources and technical assistance.


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Operation: Birthday Cake
If you have a deployed military service member to whom you'd like to send a gift cake, please make a selection from the items below. 5% of your order will also be contributed to Bake Me A Wish!s Operation: Birthday Cake program which, with our partner Soldiers Angels, donates birthday cakes each month to our valued service men and women overseas.
Frosted cakes CANNOT be sent overseas due to the length of time required for arrival of your gift.


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U.S. Sen. Debbie Stabenow will be in Southfield Wednesday to discuss initiatives to strengthen mental health services.
The 2:30 p.m. forum will be at Southfield Parks & Recreation, Room 223, 26000 Evergreen Road in Southfield.
Joining Stabenow will be representatives from local mental health authorities.
Stabenow, a Democrat, is an advocate of expanding Medicaid to give mental health treatment the same access to funding as treatment for physical ailments.
Contact Charles Crumm at 248-745-4649, firstname.lastname@example.com or follow him on Twitter @crummc and on Facebook. More information is at oaklandmichiganpolitics.blogspot.com. Keep up with the latest in local news by texting OPNews to 22700. Msg & Data Rates May Apply. Text HELP for help. Text STOP to cancel.


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Okla. House Panel To Consider Stricter Abortion Bills
An Oklahoma House panel is expected to consider a pair of bills that would tighten the requirements for girls under age 18 to notify a parent before receiving an abortion.
Both bills are scheduled to be heard Tuesday in the House Public Health Committee. The measures seek to tighten the judicial bypass policy in state law that allows girls under 18 to receive an abortion without notifying a parent if a judge approves it.
Anti-abortion proponents maintain the state's current judicial bypass option is being exploited by abortion providers who seek out judges who routinely approve the practice.
But abortion rights supporters say judicial bypass is essential for teenagers facing an unwanted pregnancy who might suffer abuse from parents or guardians that learn of the pregnancy.
(Copyright 2013 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.)


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Atlantic Furniture YBBCOLUMBIAFULLFULLALAW
YBBCOLUMBIAFULLFULLALAW Columbia Collection Full over Full Bunk Bed with Floor Length Angle Ladder: Antique Walnut
The Columbia Bunk Bed is truly the most versatile bunk we make. Our only bunk that comes in Twin over Twin, Twin over Full, Full over Full and Twin over Futon! Constructed in solid Eco-friendly Hardwood, in four high build durable finishes. The Columbia has a built in modesty panel and can accommodate under bed storage drawers or a trundle. With its 26 steel reinforcement points and two 14 piece slat kits, this bed is as sturdy as they come. So many sleep options, and it creates convenient space in your child's room. This bed will surely become their favorite sleepy time fort and you can feel good about the quality and value.� Available at AppliancesConnection
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- Brand:Atlantic Furniture
- Stock Id:196533
- Product Number:YBBCOLUMBIAFULLFULLALAW
- Series:Columbia
- Height:68.125"
- Width:58.375"
- Length:80.5"
- Bunk Bed:Yes
- Weight:270.00 lbs


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Not a good week if you're one of the better teams in the NBA. None of the Top 7 teams in last week's rankings was able to escape the week without a loss, and only the top team, Oklahoma City, was able to win more games than it lost.
Still, it should be pointed that the one loss for the Thunder came against, ahem, the Wizards. In all, the Top 7 combined to go a very wobbly 10-14 in the previous week.
Rare is the week when the top team can suffer a loss to the worst team, and still maintain the No. 1 spot. But because everyone else had such a hard time last week, the Thunder will remain on top.
1. Thunder. Scott Brooks called Sunday's 87-83 win the team's best defensive game of the year. And they needed it to beat Portland.
2. Spurs. The revamped San Antonio defense gave up triple-digit scoring just five times in December. It's already given up triple digits four times in January, though.
3. Clippers. Grant Hill finally has suited up for the Clippers, and when Chauncey Billups gets back, too, coach Vinny Del Negro is going to have some rotation questions to answer.
4. Heat. Guard Mario Chalmers missed a potential game-winning 3-pointer against the Blazers—but came back with a record 10 3-pointers to help beat the Kings.
5. Grizzlies. Rudy Gay trade rumors have been common sport in the last few weeks. But if this team really has a chance to win, why trade a position where it is weakest?
6. Nets. P.J. Carlesimo is 8-1 as the coach of the Nets, and Sunday's win over the Pacers was a good test. He has earned the right to finish the season.
7. Warriors. The Warriors' signature win this season came Dec. 12 in Miami. Golden State has lost three of four but can rekindle some magic at home Wednesday against the Heat.
8. Pacers. The offense still isn't pretty—they've scored 100-plus points four times this season—but it has been good enough to support the defense lately.
9. Knicks. On Dec. 28, the Knicks were the only team above .500 in the Atlantic and held a 6½-game lead over the Nets and Celtics. Less than three weeks later, their lead is 4½ over Boston, 2½ over Brooklyn.
10. Nuggets. That high-pressure, balanced offense is paying off. In their win over Golden State, they had nine players score eight points or more.
11. Hawks. They have been very streaky, and starting Monday with Chicago, they have a tough stretch that includes the Nets twice, plus the Spurs and Timberwolves. Bad time for a slump.
12. Bulls. Win at Miami. Five days later, lose at home to Milwaukee. Win in New York. Lose the next night at home against Phoenix. This is a tough bunch to figure.
13. Celtics. Fantastic bench play has been a hallmark of the Celtics' return to prominence. The return of Avery Bradley has helped Doc Rivers set his rotation the way he wants.
14. Blazers. A big road trip is looming in February, which means the Blazers must take advantage of the stretch of five home games out of seven in January.
15. Rockets. James Harden's scoring streak of 25-plus points ended Friday in Boston. He had 24 points in that game and, uncharacteristically, missed three free throws.
16. Bucks. Milwaukee got its four-game road trip off to a good start with a win in Toronto. With the Lakers, Suns and Blazers on tap, the Bucks have a good chance of at least splitting.
17. Jazz. They have been quietly poking around on the trade market (the Jazz tend to do their transactions quietly) for Al Jefferson and Paul Millsap, but a strong January start has to make them think twice about a major move.
18. Sixers. They got a big win Saturday over the Rockets, as Philly tries to shake its way out of a 3-13 downturn that lasted a month.
19. Timberwolves. Pity Rick Adelman. He came to Minnesota thinking he would be coaching Ricky Rubio and Kevin Love. They have been in the starting five together exactly 27 times in two years.
20. Mavericks. If you're Dwight Howard or Omer Asik, you'd sever a pinky for a 72.2 percent free-throw shooting mark. For Dirk Nowitzki, though, it's a problem.
21. Raptors. The Toronto bench outscored Milwaukee in the first and second quarters by 20 on Sunday. They were outscored in the other two quarters by 31. The bench deficit: 43-7. Depth is a bit of a problem here.
22. Pistons. Yes, yes, Andre Drummond is raw and all that. But watch him play a bit and you can't help but feel a lot of teams will regret not drafting him.
23. Lakers. The win over Cleveland stanched the bleeding of that six-game losing streak. But some bad news: Six of the next seven opponents are over .500.
24. Magic. Before pulling out a 3-point upset over the Clippers, the Magic's previous five losses had been by a combined 15 points.
25. Kings. Please. For the love of everything that is good. Someone talk to the Maloofs into just selling this team so we can all get on with our lives.
26. Hornets. The loss Sunday to the Knicks was a rarity; before that, the Hornets had been 5-1 in games in which Eric Gordon played.
27. Suns. Perhaps Marcin Gortat's trade request has been tabled. Still, he hasn't taken much of a step forward this year, and that's been a problem for the Suns.
28. Bobcats. Toronto has never been known as a defensive juggernaut. But yet the Bobcats managed just 78 points on 37.3 percent shooting Friday against the Raps.
29. Cavaliers. The 0-2 start to the Cavaliers' five-game road trip through the West didn't bode well. Because, you know, there are still three more games left.
30. Wizards. Point guard John Wall made his season debut, which means that thought the Wizards are down here at the bottom still, they could well be on their way up.


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Good luck suckers.According to league sources, the Knicks' first prong is to try to attract the Celtics' Rajon Rondo. This idea has been tossed around in various forms for a while now, it's not shocking. But the way the Knicks are hoping to get Rondo is a little unusual.
It's not in free agency in 2015 but later this season or next summer when he comes back from a torn ACL. The Knicks are hoping Rondo will be interested in making a maneuver similar to what Anthony did back in 2011 and eventually try to force a trade to the Knicks, sources said.
The Celtics have consistently denied they want to trade Rondo. But once this trade deadline passes, and it isn't clear if he will even play before February, Rondo will have only one guaranteed season left on his contract. Like with Anthony when he applied pressure to the Denver Nuggets by threatening to leave in free agency, the Knicks wonder if Rondo will be able to have a say in where he might be traded if the Celtics end up fearful he'll leave in free agency.
That may seem contrived, yes, but this isn't a made-up scenario. It is a genuine option. You have to give the Knicks this: It has worked before.
If that fails -- and who knows how Rondo will mesh with this Celtics team, it could work well and he could want to stay -- the Knicks fully believe they will get one or two of the following in free agency in 2015 when they expect to have large salary-cap space: Kevin Love, LaMarcus Aldridge, Roy Hibbert, Marc Gasol, Tony Parker or Rondo when his contract is up. Under certain circumstances, James himself could be a free agent again that summer.


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With more than 140 fields of study, there are many reasons to attend Temple summer sessions.
- Spend uninterrupted time on a challenging course.
- Lighten your load next semester by getting required courses out of the way.
- Graduate early by taking classes during the summer.
Temple offers courses on five different campuses throughout the Philadelphia area and Harrisburg. With day, evening and online courses offered during the summer, you'll find it's easy to continue your studies whenever—and wherever—you choose. Learn more about summer sessions at Temple.


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Viktoria Plzen confirmed themselves as one of the dark horses in this year's Europa League after shocking Napoli 3-0 in the first leg of the last-32 tie at San Paolo.
Plzen beat defending champions Atletico Madrid to top their group and are now heavy favourites to progress past the high-flying Italians after late goals from Stanislav Tecl and Frantisek Rajtoral built on Vladimar Darida's first-half opener.
Anzhi Makhachkala recovered from a goal down to defeat Hannover 3-1 although the Russian side will hope they will not be made to rue Samuel Eto'o's missed second-half penalty.
Hannover took a 22nd-minute lead through Szabolcs Huszti but Eto'o drew Anzhi level soon after and Odil Ahmedov put the hosts ahead immediately after half-time.
Eto'o then spurned the chance to make it 3-1 in the 57th minute when his spot-kick was saved by Ron-Robert Zieler, but Anzhi were still able to secure a two-goal lead to take to Germany for the second leg thanks to Mbark Boussoufa.
Levante put aside their poor domestic form to claim an impressive 3-0 victory over 10-man Olympiacos that leaves them within touching distance of a place in the last 16.
The Spanish outfit out had lost five of their last six in league and cup prior to tonight but goals from Pedro Rios, Jose Barkero and Obafemi Martins earned Juan Ignacio Martinez's men a notable scalp against a side who were playing in the Champions League group stages before Christmas.
Oleg Gusev missed a second-half penalty as wasteful Dynamo Kiev played out a 1-1 draw with Bordeaux.
The Ukrainian hosts dominated the contest and took a deserved lead through Lukman Haruna, but that was cancelled out within minutes by Ludovic Obraniak.
Goals by Toby Alderweireld and Ricardo Van Rhijn guided Ajax to a 2-0 victory over 10-man Steaua Bucharest at the Amsterdam ArenA.
Oscar Cardozo's second-half strike was enough to ensure Benfica will take a slender advantage back to the Estadio da Luz against Bayer Leverkusen.
Meanwhile, Fenerbahce held BATE Borisov to a goalless draw in their Europa League first leg in Belarus despite playing all bar the first three minutes with 10 men after Raul Meireles was sent off early on.
Two goals for Lazio from Libor Kozak as well as three penalties for Borussia Monchengladbach saw a breathless match end with the 10-man Italian club in pole position ahead of the second leg.
Martin Stranzl's penalty put the Bundesliga side ahead before Sergio Floccari and Kozak turned the pendulum Lazio's way.
Stranzl then missed his second penalty, which also saw Andre Dias dismissed following his second yellow card, before three goals in six minutes brought a pulsating 3-3 draw to an end.
Atletico Madrid look to be heading out after they were beaten 2-0 at home by Rubin Kazan.
Gokdeniz Karadeniz put the Russians ahead after six minutes before Pablo Orbaiz doubled their advantage in added on time.
Juande Ramos' chances of becoming only the second manager to win the Europa League for a third time may have to wait another year after his Dnipro side were beaten 2-0 by Basle at St Jakob-Park.
Ramos had won the trophy twice before at Sevilla and a third triumph would put him level with Republic of Ireland boss Giovanni Trapattoni.
However a first-half goal from Valentin Stocker and a second-half strike from Marco Streller ensured the Swiss side head into next week's second leg at the Dnipro Stadium in control.
A last-minute goal from Glynor Plet gave Genk a precious away goal as they held Stuttgart 1-1 at the Mercedes-Benz Arena.
Christian Gentner had fired the hosts ahead before half-time, but Plet struck in stoppage time to level the scores and give his team the advantage heading into the return match in Belgium next week.
Rodrigo Palacio scored twice following his early entrance as a substitute to put Inter Milan in control of their tie against Cluj.
Palacio, a 10th-minute replacement after a serious-looking injury to Diego Milito, scored 10 minutes after that and added a late second in a 2-0 win.


text: This news item expired on 6/25/2014, so the information below could be outdated or incorrect. Comedy Western Film: Cat Ballou - TODAY Pack Memorial Library 67 Haywood Street 250-4700 Join us for a free film series of comedy westerns on Wednesday afternoons. All films will be shown at 3 p.m. in Lord Auditorium at Pack Library. The film schedule will be: June 25 – Cat Ballou (1965) starring Jane Fonda, Lee Marvin and Michael Callen July 2 – ¡Three Amigos! (1986) starring Steve Martin, Chevy Chase and Martin Short


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New Mobile Catalog
The Libraries are happy to announce the launch of our new mobile catalog interface athttp://libweb.grinnell.edu/m/. Search the library catalog, keep a list of saved items, IM a librarian, or check library hours all on your mobile device. You can also access a few of your favorite databases in our Mobile databases list.
More features coming soon! Please let us know if you have any feature suggestions atquery[at]grinnell[dot]edu.


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Terrence wrote:My arm was jelly when I played three 24 hole rounds in a day.
Yeah that happens. I did notice that my last round was my best. I wasn't throwing hard and was just focusing more on form and release then power. Seems that my Zen-Disc-Golfing is my best rounds.


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What education experts say about good schools
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Does competition make schools better?
CTA QEIA pays off
Encuentros program shows youths path to success
Students create pottery, donate to the hungry
Capistrano educators call for strike
Human Rights Award winners
Good Teaching Conference: What members had to say
State Council announces election endorsements
As May Revision looms, CTA fights to protect schools
CTA-opposed measure would gut teachers' rights
Shared school leadership that improves student learning
Heads up: Deadlines and conference dates
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Posted 7 years ago
(2 items)
I know this is a counterfeited album, one that is ripped off a lot; I also know that everywhere I look my album seems to be legit. I just can't figure out an appropriate value. It is in perfect condition. Plastic is opened, not sealed. Was bought in Canada at some time by my father. I know more information may be needed, but I am not sure what. Would love to have some help on this one. Thanks!
-Brenda, Fort Collins, CO


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Earlier Breast Cancer Detection Using Automated Whole Breast Ultrasound With Mammography, Including Cost Comparisons
Recruitment status was: Recruiting
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
|Breast Neoplasms Ultrasonography
|Procedure: Comparison of Automated Whole Breast Ultrasound Screening with Blinded Screening Mammography
|Study Type:
|Study Design:
|Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Screening
|Official Title:
|Earlier Breast Cancer Detection Using Automated Whole Breast Ultrasound With Screening Mammography, Including Cost Comparisons
- Numbers of breast cancers detected [ Time Frame: One year after sonocine screening ]
|Estimated Enrollment:
|Study Start Date:
|January 2003
|Estimated Study Completion Date:
|January 2010
|Estimated Primary Completion Date:
|July 2008 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: 1
Adjunct screening with sonocine
Procedure: Comparison of Automated Whole Breast Ultrasound Screening with Blinded Screening Mammography
AWBU is a computer-based system for performing and recording ultrasound scans of the whole breast. The transducer of any suitable high-resolution compound ultrasound equipment is attached to a mechanical arm guided by computer, and images are acquired in longitudinal rows, overlapping to assure complete coverage. The mechanical arm controls transducer speed and position, with a technician maintaining appropriate contact pressure and orientation vertical to the skin. Approximately 150-300 images per row are immediately displayed on the AWBU monitor, then permanently stored.
The AWBU software creates a continuous ciné loop of the images, creating the appearance of real-time scanning. With spatial registration, any point on an image can be identified as a distance from the nipple in a specific radius. Image review is optimized by playback on a high-resolution monitor to allow compressed image size, 3-D reconstruction, and adjustment of contrast, brightness and review speed.
Other Names:
Show Detailed Description
|Ages Eligible for Study:
|35 Years to 90 Years (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- be at least 35 years old, unless she has a strong pre-menstrual family history of breast cancer
- have had no screening mammogram in the past 10 months
- agree to have a screening mammogram that will not be reviewed until after a SonoCiné is performed
- agree to have a screening mammogram in approximately one year
- agree to answer follow up question in approximately one year
- meet the usual criteria for breast screening (be asymptomatic of focal breast disease)
- have no history of breast cancer for at least one year
- agree to have both mammogram and SonoCiné if a physical finding or mammographic finding occurs within one year that requires biopsy
Exclusion Criteria:
- greater than 7 cm compressed breast thickness at mammography
Please refer to this study by its ClinicalTrials.gov identifier: NCT00649337
|Contact: Kevin M Kelly, M.D.
|United States, California
|Huntington Memorial Hospital/Hill Breast Center
|Pasadena, California, United States, 91105
|Contact: Karen Esser
|Principal Investigator:
|Kevin M. Kelly, M.D.
|SonoCine, Inc.
Additional Information:
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
|Responsible Party:
|Kevin M. Kelly, M.D., SonoCine, Inc.
|ClinicalTrials.gov Identifier:
|NCT00649337 History of Changes
|Other Study ID Numbers:
|Study First Received:
|February 25, 2008
|Last Updated:
|March 27, 2008
Keywords provided by SonoCine, Inc.:
breast cancer
Additional relevant MeSH terms:
Breast Neoplasms
Neoplasms by Site
Breast Diseases
Skin Diseases
ClinicalTrials.gov processed this record on September 25, 2017


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County Seeks Community Input on Little Hunting Creek Watershed Plan
Office of Public Affairs
12000 Government Center Parkway, Suite 551
Fairfax, VA 22035-0065
Nov. 17, 2003
County Seeks Community Input on Little Hunting Creek Watershed Plan
On Wednesday, Dec. 3, 2003, Fairfax County will sponsor a Draft Plan Review Workshop from 6 to 9 p.m. at the Carl Sandburg Middle School, 8428 Fort Hunt Rd., Alexandria, to seek citizen input on the first draft of the watershed management plan for Little Hunting Creek. There will be an orientation for those new to the plan at 6 p.m. and the full plan will be presented at 6:30 p.m. At 7 p.m., participants will then have the opportunity to tour stations where elements of the plan will be described by project engineers. Participants will review and contribute to ideas for restoring the watershed.
The county will develop similar plans for all 30 of its watersheds, the areas that drain to particular streams, all of which empty into the Potomac River and eventually the Chesapeake Bay. The Little Hunting Creek watershed management plan provides a consistent basis for evaluating problems and implementing solutions. The goal is to protect and restore the stream and related natural resources, such as wildlife habitat. As part of the development of each management plan, county staff are working with local communities to generate solutions to problems identified in their watersheds. Fred Rose of the county's Stormwater Management Branch explains, "The goal is to have the best possible plan for the community, by the community."
The Little Hunting Creek watershed planning process began in December 2002 and will be completed by spring 2004.The county has hired the team of Woolpert LLP and the University of Virginia's Institute for Environmental Negotiation to encourage community involvement, analyze data on existing watershed problems, and provide recommendations on how to solve them. The community involvement process includes a steering committee comprised of 14 community representatives from neighborhoods, businesses, conservation groups and other local interests. In addition to seeking input from the steering committee, the county held a public watershed forum in July and conducted two focus groups to gain insight into how the plan should be developed. The workshop on Dec. 3 will showcase the strategy proposed by the community and local businesses for restoring the watershed of Little Hunting Creek. Community review of this first draft plan is critical to ensuring the plan is realistic and that the strategy will help make progress toward improving the watershed's condition and the quality of life for residents and businesses.
Little Hunting Creek originates in Huntley Meadows Park and flows into the Potomac River at Mount Vernon. With its major tributaries, North Branch and Paul Spring Branch, it drains an 11.25-square mile watershed that is primarily residential and commercial, including the Route 1 corridor. A recently completed physical assessment of over 800 miles of streams in Fairfax County, combined with ongoing biological monitoring by local volunteers, has provided valuable information on current conditions in Little Hunting Creek. This watershed suffers from problems common to older, developed urban watersheds – paved land cover, loss of natural buffers, flooding, stream bank erosion, polluted runoff and trash.
Children are welcome to attend the workshop. Advance registration is not required but will help coordinators to ensure adequate space. To register, please send an e-mail to firstname.lastname@example.com or call 703-684-4460, TTY 711.
The watershed planning program is administered by the Stormwater Planning Division of the Fairfax County Department of Public Works and Environmental Services. Information can be found on the project's Web page by clicking on the Little Hunting Creek Watershed at www.fairfaxcounty.gov/dpwes/Watersheds/ and click on "Get involved in your watershed" and then on "Little Hunting Creek."
For additional information, contact Fred A. Rose,
P.E., chief, Stormwater Management Branch or Paul Shirey, P.E., program
manager, at 703-324-5500, TTY 711.