text:
Groene at the Legislature: Teacher absences, substitutes
Mail: Southern statues symbolize suppression
More opinion
Senate: Vote no on Graham-Cassidy health care plan
Fall: Good time to spray musk thistle in rosette stage
More Ag News
The University of Nebraska-Lincoln and other land-grant universities across the nation celebrate the Morrill Act this year, the federal act that created land-grant universities.
UNL will hold a week of activities Sept. 23-29 to celebrate the 150th anniversary of the act.
The Morrill Act opened higher education for Americans who previously could not afford to go to college, said Ronnie Green, the Harlan vice chancellor of the Institute of Agriculture and Natural Resources at NU.
"Nebraska should be proud of the advancements made in food, fuel, water and landscapes for the people of our great state and those around the world," Green said.
The celebration includes:
Sept. 23 from noon-5 p.m., the Agricultural Research and Development Center near Mead will celebrate 50 years of research and education through exhibits, presentations, bus tours, food, fun and learning.
Sept. 24 from 3-6 p.m. at the Nebraska East Union, an entrepreneurship fair will feature alumni and current students. Students also are invited to participate in a quick-pitch competition for a chance to win an iPad.
Sept. 25 from 8:30 a.m.-2 p.m. at the Nebraska East Union, a Life Sciences Symposium with featured speaker Sonny Ramaswamy, news director of USDA's National Institute of Food and Agriculture. And, from 2:30-4:30 at UNL's Maxwell Arboretum, a tree planting will be incorporated with an America Forests Grant and ReTree Week. And, from 5-8 at UNL's Hardin Hall, wildlife of all kinds will be available to view up close and personal.
Sept. 26 will showcase study abroad tours, international sabbaticals and Fulbright scholars. Food from around the world will be served during this event from 3-6 p.m. in Hardin Hall on UNL's East Campus.
Rural Futures Day will be Sept. 27, offering updates from May's Rural Futures Conference. This event will be from 10:30 a.m.-noon at Pinnacle Bank, 210 E. 23rd Street in Columbus. U.S. Secretary of Agriculture Tom Vilsack is invited.
Also on Sept. 27, "Backyard Farmer" will celebrate its 60th anniversary with a live broadcast outside Hardin Hall on UNL's East Campus from 6-9 p.m.
Sept. 28, starting at 7:30 p.m., the week's celebration will culminate with a scheduled forum of former U.S. Secretaries of Agriculture, led by Nebraska's Clayton Yeutter and Mike Johanns at the Lied Center for Performing Arts, 12th and R streets in Lincoln. The forum will be the first Heuermann Lecture (http://heuermannlectures.unl.edu/) for 2012-13.
Tickets, while free, are needed for this lecture and can be reserved starting Aug. 28 by contacting the Lied Center ticket office between 11 a.m. and 5:30 p.m. Monday through Friday at 402-472-4747; 1-800-432-3231. Ticket holders are asked to be in the lobby by 7:15 p.m. Sept. 28; unclaimed tickets will be released at that time.
To end the festivities, an Institute of Agriculture and Natural Resources tailgate party will be held before the Nebraska-Wisconsin game. The tailgate will be at the Nebraska East Union from 3-7 p.m. UNL alumni, current students and IANR stakeholders can enjoy food, festivities and a shuttle ride to the football game.
For more information or for questions, contact Jill Brown, IANR director of external relations at firstname.lastname@example.com; 402-472-2871
For a detailed schedule of events, visit http://landgrant.unl.edu/.
Flatrock Publishing, Inc.
1300 E 4th St., Suite F
North Platte, NE 69101


text:
Cisco Is Peaking
Cisco Systems (CSCO) appears to have lost its upside momentum. Since mid-November, the stock has been tracing out a bullish channel. Heading into this week, shares had risen over 20% over the past 10 weeks.
This impressive run began with a strong first-quarter report back on Nov. 14. Cisco began the run with a powerful gap-higher open and has suffered very little in the way of a pullback since. Over the past couple of weeks, signs of a midterm top have been growing....209 more words left in this article. To read them, just click below and try Real Money FREE for 14 days.
There's no substitute for a trading floor to get great ideas, so Jim Cramer created a better one at Real Money and blogs there exclusively. We then added legendary hedge fund manager, Doug Kass, with his exclusive Daily Diary and best investing ideas. Staffed with more than 4 dozen investing pros, money managers, journalists and analysts, Real Money Pro gives you a flood of opinions, analysis and actionable trading advice found nowhere else, and allows you to interact directly with each expert.
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subset: commoncrawl


text:
Everolimus (RAD001) Therapy for Epilepsy in Patients With Tuberous Sclerosis Complex (TSC)
This study has been completed.
Children's Hospital Medical Center, Cincinnati
Information provided by (Responsible Party):
Children's Hospital Medical Center, Cincinnati
ClinicalTrials.gov Identifier:
First received: February 15, 2010
Last updated: February 1, 2017
Last verified: February 2017
- Full Text View
- Tabular View
- Study Results
- Disclaimer
- How to Read a Study Record
Detailed Description:
The goal of this study is to learn if the study drug RAD001 can reduced the number of epileptic seizures, and can be taken safety by people who have epilepsy associated with Tuberous Sclerosis Complex.
|Epilepsy Tuberous Sclerosis Complex
|Drug: Everolimus
|Phase 1 Phase 2
|Study Type:
|Study Design:
|Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
|Official Title:
|Everolimus (RAD001) Therapy for Epilepsy in Patients With Tuberous Sclerosis Complex
Resource links provided by NLM:
Genetics Home Reference related topics: pyridoxal 5'-phosphate-dependent epilepsy tuberous sclerosis complex
MedlinePlus related topics: Epilepsy Tuberous Sclerosis
Drug Information available for: Sirolimus Everolimus TemsirolimusU.S. FDA Resources
Further study details as provided by Children's Hospital Medical Center, Cincinnati:
Primary Outcome Measures:
- Reduction in Seizure Frequency [ Time Frame: Baseline (Weeks 1-4), Week 16 ]The primary efficacy endpoint was the percentage of participants demonstrating a 50% or greater reduction in seizure frequency at the end of the maintenance phase (weeks 13-16) compared to baseline (weeks 1-4)
- Number of Participants Continuing Study Medication Over Time [ Time Frame: Individual subjects will be assessed every 6 months for up to 48 months; aggregate analysis will take place at end of study ]
|Study Start Date:
|January 2010
|Study Completion Date:
|April 2016
|Primary Completion Date:
|April 2016 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: Everolimus
Subjects will be administered study drug if they meet study criteria after 4 weeks of baseline phase. The starting dose will be 5 mg/m2/day, rounded to the nearest 2.5 mg/dose, to be taken daily.
Drug: Everolimus
Everolimus is available in tablet form. The starting dose will be 5 mg/m2/day, rounded to the nearest 2.5 mg/dose, to be taken daily. After two weeks, serum trough level will be measured and dose adjusted according to the following algorithm If Blood trough level is less than 2.5 ng/ml than increase dose by 5 mg/m2/day; If Blood trough level is 2.5-5.0 ng/ml than increase dose by 2.5 mg/m2/day; If Blood trough level is 5.1-10.0 ng/ml than increase dose by 0 mg/m2/day (no change); If Blood trough level is 10.1-15.0 ng/ml than decrease dose by 2.5 mg/m2/day
Other Names:
Detailed Description:
Tuberous sclerosis complex (TSC) is a genetic disorder with an incidence at birth of 1 in 6000. This disorder is characterized by the development of benign tumors in multiple organ systems, including the brain. The primary neurological manifestations of TSC are epilepsy, mental retardation and autism. Epilepsy is most common, occurring in 80-90% of patients, and often the seizures are severe, unremitting, and uncontrolled by current anticonvulsant medications. It is generally accepted that the seizures arise from cortical and subcortical tubers and surrounding tissue in the brain. These tubers are caused by mutations in the tumor suppressor genes TSC1 or TSC2. The protein products of these genes, hamartin and tuberin, act as negative regulators of the PI3K/PKB(Akt)/mTOR signaling pathway that regulates cell growth and proliferation Everolimus is an immunosuppressant drug that also inhibits mTOR signaling and is capable of reversing aberrant mTOR-dependent effects that occur when hamartin or tuberin are absent or defective. Thus, we hypothesize that drugs like everolimus may be therapeutically useful for the treatment of refractory epilepsy in patients with TSC.
|Ages Eligible for Study:
|2 Years and older (Child, Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Male or female individuals aged two years and older.
- History of epilepsy and at least eight reported seizures in previous 30 days prior to informed consent
- Failure of two or more approved antiepileptic drug therapies
- Clinically definite diagnosis of tuberous sclerosis (modified Gomez criteria or positive genetic test)
- Parents/Caregivers are English-speaking (primary or secondary language acceptable)
- If female and of child bearing potential, documentation of negative pregnancy test at time of informed consent. Sexually active pre-menopausal female or male patients must use adequate contraceptive measures, excluding use of estrogen-containing birth control contraceptive regimen while on study medication. Prior hysterectomy, tubal ligation, complete abstinence, barrier methods which include both a cervical diaphragm and spermicidal jelly, intrauterine devices (IUD), progesterone based contraceptives, or vasectomy in partner are all acceptable forms of contraception
- Adequate bone marrow function as shown by ANC ≥ 1.5 x 109/L, Platelets ≥ 100 x 109/L, and Hb >9 g/dL
- Adequate liver function as shown by serum bilirubin ≤ 1.5 x upper limit of normal (ULN), ALT and AST ≤ 2.5x ULN, INR and PTT ≤1.5. (Anticoagulation is allowed if target INR ≤ 1.5 on a stable dose of warfarin or on a stable dose of LMW heparin for >2 weeks at time of randomization.)
- Adequate renal function as shown by a serum creatinine ≤ 1.5 x ULN
- Fasting serum cholesterol ≤300 mg/dL OR ≤7.75 mmol/L AND fasting triglycerides ≤ 2.5 x ULN. NOTE: In case one or both of these thresholds are exceeded, the patient can only be included after initiation of appropriate lipid lowering medication
Exclusion Criteria:
- Significant hematological or hepatic abnormality (i.e., transaminase levels > 2.5 x ULN or serum bilirubin >1.5 x ULN, Hemoglobin < 9 g/dL, platelets < < 100 X 109/L , absolute neutrophil count < 1.5 x 109/L)
- Patients currently receiving anticancer therapies or who have received anticancer therapies within 4 weeks of the start of study drug (including chemotherapy, radiation therapy, antibody based therapy, etc.)
- Patients, who have had a major surgery or significant traumatic injury within 4 weeks of start of study drug, patients who have not recovered from the side effects of any major surgery (defined as requiring general anesthesia) or patients that may require major surgery during the course of the study
- Prior treatment with any investigational drug within the preceding 4 weeks prior to informed consent
- Patients receiving chronic, systemic treatment with corticosteroids or another immunosuppressive agent. Topical or inhaled corticosteroids are allowed
- Patients should not receive immunization with attenuated live vaccines within one week of informed consent or during study period
- Patients with coexisting malignancies within past 3 years, except for adequately treated carcinoma of the cervix or basal or squamous cell carcinomas of the skin
- Uncontrolled brain or leptomeningeal metastases, including patients who continue to require glucocorticoids for brain or leptomeningeal metastases
Patients who have any severe and/or uncontrolled medical conditions or other conditions that could affect their participation in the study such as:
- Symptomatic congestive heart failure of New York heart Association Class III or IV, unstable angina pectoris, symptomatic congestive heart failure, myocardial infarction within 6 months of start of study drug, serious uncontrolled cardiac arrhythmia or any other clinically significant cardiac disease
- Severely impaired lung function defined as spirometry and DLCO that is 50% of the normal predicted value and/or 02 saturation that is 88% or less at rest on room air and/or requirement for continuous supplemental O2
- Uncontrolled diabetes as defined by fasting serum glucose >1.5 x ULN
- Active (acute or chronic) or uncontrolled severe infections
Liver disease such as cirrhosis, chronic active hepatitis or chronic persistent hepatitis
- A known history of HIV seropositivity
- Impairment of gastrointestinal function or gastrointestinal disease that may significantly alter the absorption of everolimus (e.g., ulcerative disease, uncontrolled nausea, vomiting, diarrhea, malabsorption syndrome or small bowel resection)
- Patients with an active, bleeding diathesis
- Female patients who are pregnant or breast feeding, or adults of reproductive potential who are not using effective birth control methods.
- Patients who have received prior treatment with an mTOR inhibitor (sirolimus, temsirolimus, everolimus).
- Patients with a known hypersensitivity to RAD001 (everolimus) or other rapamycin (sirolimus, temsirolimus) or to its excipients
- History of noncompliance to medical regimens
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01070316
Please refer to this study by its ClinicalTrials.gov identifier: NCT01070316
|United States, Ohio
|Cincinnati Children's Hospital Medical Center
|Cincinnati, Ohio, United States, 45229
|United States, Texas
|Baylor College of Medicine
|Houston, Texas, United States, 77030
Sponsors and Collaborators
Children's Hospital Medical Center, Cincinnati
|Principal Investigator:
|Darcy Krueger, M.D. Ph.D
|Children's Hospital Medical Center, Cincinnati
More Information
Keywords provided by Children's Hospital Medical Center, Cincinnati:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on September 21, 2017
|Responsible Party:
|Children's Hospital Medical Center, Cincinnati
|ClinicalTrials.gov Identifier:
|NCT01070316 History of Changes
|Other Study ID Numbers:
|Study First Received:
|February 15, 2010
|Results First Received:
|August 1, 2016
|Last Updated:
|February 1, 2017
|Individual Participant Data (IPD) Sharing Statement:
|Plan to Share IPD:
Keywords provided by Children's Hospital Medical Center, Cincinnati:
Tuberous Sclerosis Complex
Mammalian Target of Rapamycin (MTOR)
Additional relevant MeSH terms:
Tuberous Sclerosis
Pathologic Processes
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Neoplasms, Multiple Primary
Neoplastic Syndromes, Hereditary
Malformations of Cortical Development, Group I
Malformations of Cortical Development
Nervous System Malformations
Neurocutaneous Syndromes
Heredodegenerative Disorders, Nervous System
Neurodegenerative Diseases
Congenital Abnormalities
Genetic Diseases, Inborn
Antineoplastic Agents
Immunosuppressive Agents
Immunologic Factors
Physiological Effects of Drugs
Anti-Bacterial Agents
Anti-Infective Agents
Antibiotics, Antineoplastic
Antifungal Agents
ClinicalTrials.gov processed this record on September 21, 2017


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6" 2001-2006 GM Avalanche 2500 4WD IFS Lift Kit
If quality and performance is what you demand, then you've come to the right place! The Zone HD system is built to withstand the trail as well as make a great daily driver. The once piece main crossmembers in combination with the CNC machined steering knuckles create OE style geometry for the ride you demand. The differential skid plate and the compression struts offer off-road protection for the serious trails. Combine this with vehicle specific valve Zone shocks and you have a winning combination all made in the USA!
- One piece 1/4" steel crossmembers
- CNC machined ductile iron steering knuckles
- Differential skid plate with compression struts for offroad protection
- Rear block kit for easy installation
Installation Instructions
Here is a customers pickup that was brought in, and he wanted a 6" lift. So a 6" lift he got!Posted by Jack-It, Inc. on Thursday, February 26, 2015
Additional Information
|Item Number
|Manufacturer Part Number
|Important Notes
|Torsion bar unloading/loading tool required.
To reduce trimming on new body style HD's 20" wheel with 5 3/4" backspacing recommended.
Gas models required minor exhaust modification to clear front driveshaft.
Also fits Avalanche/Suburban 2500 models.
Minor welding required.
Frame bracket and differential mount modifications required.
|Chevy, GMC
|Avalanche 2500
|Year Spans


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Illegal water diversion, likely for marijuana grows, are sucking the life from the Eel River in Mendocino and Humboldt counties. This fall, river dives by biologists have confirmed low flows and excessive nutrient loads have created abundant mats of toxic algae, despite "normal" early season flows.
While blaming legal water diversions for this deterioration has been popular, it may be time to face the true culprit, illegal marijuana grows.
Biologists with the Eel River Recovery Project attempted to monitor this year's returning Chinook salmon population at Ferndale. They found the "flow of the Eel and its tributaries were approximately half of the long-term averages for the date despite rainfall being in the 'normal' range. Thick mats of algae lined the shore of the lower Eel River.
"Divers in the Weymouth Pool below Howe Creek encountered floating algae mats and many contracted swimmer's itch. Thick mats of algae also covered the stream bottom and could create adverse conditions for salmon and steelhead, such as depressed dissolved oxygen."
Many continue to blame the Lake Pillsbury project which diverts Eel River water to the Russian River for this deterioration. While this public diversion of water has received massive protests and attention, it appears the illegal diversions have had an even greater impact on drying up the Eel River.
While legal diversions from either the dams at Willits, Brooktrails or Lake Pillsbury are required to release any water flowing into the reservoirs during the dry summer months into the Eel River, illegal diversions face no such enforcement.
To avoid contamination of the data from legal diversions, TWN studied the South Fork of the Eel River. The South Fork has no dams or other controversial diversions along its entire length.
The South Fork begins in the headwaters at Cahto Peak near Laytonville and meanders north through extensive public and timber lands until it joins the main stem of the Eel River near Weott.
Daily water flow rates on the South Fork of the Eel River have been kept since 1965 at Leggett and since 1939 at Miranda in Humboldt County. Average water flows since 2001 have been about 9 percent higher going into July at Leggett than the average of the past 47 years, and yet by September water flows are as much as 57 percent lower.
At Miranda the past 10 years sported 49 percent higher flows in late June than the average of the past 47 years, and yet by September it is 60 percent lower.
Comparing the daily long-term average to the most recent 10-year average at Miranda suggests about 27 million gallons per day is being diverted within the watershed.
While much of the 689 square miles of the South Fork watershed is public lands or owned by large timber companies, about half-especially east of Highway 101--is privately owned. Logging operations in the area, which have become more and more regulated and restricted through the years, have substantially ground to a halt.
The marijuana agri-complex in Mendocino and Humboldt counties has been estimated at more than $1 billion. Estimates suggest a minimum of 2 million thirsty marijuana plants are sucking up illegally diverted water each day during the summer months.
Others believe this estimate to be far short of the reality. In 2010--the last full year of Campaign Against Marijuana Planting operations--572,000 plants were removed in Mendocino County, along with hundreds of pounds of processed marijuana. Some law enforcement officers estimate this represented 10 percent or less of the total being grown here.


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This past April we got the chance to stop by to the Original Parts Group Inc. car show in Seal Beach, and we were just blown away at how this show had a steady crowd rolling in through out the day. With specials and sales going on through out the day, people took advantage of the car show and event specials that were going on through out the day.
The show had several Chevrolet Monte Carlos, Chevelle's, Buick Riviera's, Cadillac's, and GTO's displayed through out the parking lot. With music playing from the DJ systems and food from local vendors, this made up for an almost perfect atmosphere. So if you owned a lowrider, custom or muscle car, this was the place to be.
With over 200 different cars and about 5,000 people enjoying the show throughout the day, you know that this show can only continue to keep getting even stronger.


text:
Moderator: Mahavihara moderator
Ben wrote:Hi all
Just a reminder that in answering this question, please provide evidence exclusively from the suttas.
Many thanks!
"And what is the right view that has fermentations, sides with merit, & results in acquisitions? 'There is what is given, what is offered, what is sacrificed. There are fruits & results of good & bad actions. There is this world & the next world. There is mother & father. There are spontaneously reborn beings; there are priests & contemplatives who, faring rightly & practicing rightly, proclaim this world & the next after having directly known & realized it for themselves.' This is the right view that has fermentations, sides with merit, & results in acquisitions.
Chris wrote:I wonder if someone can clarify this for me please - what is the scriptural
basis for instantaneous rebirth? Is immediate rebirth mentioned anywhere in the
Sutta Pitaka?
The perceiving of impermanence, bhikkhus, developed and frequently practiced, removes all sensual passion, removes all passion for material existence, removes all passion for becoming, removes all ignorance, removes and abolishes all conceit of "I am."
http://www.accesstoinsight.org/tipitaka ... .than.html
I designate the rebirth of one who has sustenance, Vaccha, and not of one without sustenance.
Just as a fire burns with sustenance and not without sustenance, even so I designate the rebirth of one who has sustenance and not of one without sustenance."
"But, Master Gotama, at the moment a flame is being swept on by the wind and goes a far distance, what do you designate as its sustenance then?"
"Vaccha, when a flame is being swept on by the wind and goes a far distance, I designate it as wind-sustained, for the wind is its sustenance at that time."
"And at the moment when a being sets this body aside and is not yet reborn in another body, what do you designate as its sustenance then?"
"Vaccha, when a being sets this body aside and is not yet reborn in another body, I designate it as craving-sustained, for craving is its sustenance at that time."
Chris wrote:I'd be interested in your thoughts after reading this:
Is Rebirth Immediate - A Study of Canonical Sources ~ Piya Tan
Dhammanando wrote:In conventional truth a gandhabba is a being who has just passed away with ignorance and craving unextinguished, and who is propelled by kamma to the ovum as it's being fertilized.
Dhammanando wrote:... the Theravada rejected the idea of an intermediate state at the Council of Patali.
Dhammanando wrote:... in the schools that teach the intermediate state, the being in this state is said to have all the aggregates.
Dhammanando wrote:I would say that conventional speech is not really adequate for describing the mechanism of rebirth, beyond the bare suttaic account of mum, dad and gandhabba. For more detail than that we need to frame the question and answer in abhidhammic terms.
... isn't likely to be found. But it appears the khandas would be understood to be already present if one takes a gandhabba as an intermediate being. The khandas already would be taken up, so the suttas interpreted that way would seem to support the instantaneous understanding. Unless I'm missing something here (and please let me know if that's the case!).Chris wrote:I am specifically wanting to see where the Buddha clearly taught in the Suttas, that, on the death of the physical body, the taking up of another set of khandas is instantaneous.
Jechbi wrote:(p.s., where is Bhante these days?)
Is immediate rebirth mentioned anywhere in the Sutta Pitaka?
Ben wrote:Basically, Bhante says that there
Return to "Classical Theravāda"
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text:
The ink may barely be dry on 16-year-old Casco Owens' Colorado driver's license, but you'll be able to find her out competing in the brackets at nearby Bandimere Speedway. You see, Caci, as she is known, comes from family of certifiable Chevrolet high-performance "nuts," and we mean that in a very good way.
For beginners, Caci's stepfather, Scot, alternates rides between a blown big-block '55 Chevrolet Pro Streeter and a one-of-a-kind, 50th Anniversary Corvette GTR. The vehicle of choice for Brenda, Caci's mom, is a blown 406-cid, small-block Chevrolet-powered, hugger orange '69 Camaro SS. Then there's Caci's older sister Ambr, whose favorite ride is a 350-powered '62 Chevy II. Caci and her father purchased this marina blue '67 Chevelle last year for the meager sum of $7,500.
Undoubtedly, one of the most notable aspects of Caci's Chevelle is its 4-inch Harwood fiberglass cowl-induction hood, and a '64 Ford Thunderbolt-style ram air induction system, which feeds air to a Madcap Racing-prepared 355-cid GM small-block equipped with a COMP cam, Edelbrock intake, and 650 Carter AFB. Other go-fast goodies on Caci's small-block include a GM HEI, and Walker Dyno-Max headers flowing through a set of Flowmaster mufflers. Backing it all up is a stock GM Powerglide transmission.
The Chevelle's chassis features a 2.73:1-geared 12-bolt rear axle with Monroe shocks and stock Chevelle drum brakes. Monroes also control the bumps up front. Wheels and tires on the '67 are 15-inch Weld Drag Lites wrapped with a set of 15-inch Remington radial rubber.
On the inside, Caci's '67 features the factory marina blue vinyl, along with a Grant GT steering wheel and a Panasonic sound system.
Caci learned to drive with this car, and next year when she hits her Sweet 16, she'll be piloting the car to high school.


text:
Swampscott Public Library; circulation desk.
Swampscott Public Library; circulation desk.
Title provided by cataloger; Date estimated
61 Burrill Street, Swampscott, MA, 01907
Photograph is a side view of librarian Susan Duval Nellis at the circulation desk checking out books to a male patron. Photograph is pre-1955, before the first addition was made to the building.;Library was built in 1915 on land donated by Elihu Thomson, formerly the site of his tennis courts. On January 20, 1917, the library moved to its present location on Burrill Street.
Nellis, Susan Duval.
Swampscott Public Library (Swampscott, Mass.)
Libraries -- Massachusetts -- Swampscott -- Pictorial works; Library buildings -- Massachusetts -- Swampscott -- Pictorial works.
Swampscott (Mass.) -- History -- Pictorial works.
Collection :
Tags :
Citation :
"Swampscott Public Library; circulation desk.," in NOBLE Digital Heritage, Item #7954, http://heritage.noblenet.org/items/show/7954 (accessed September 26, 2017).


text:
Angioplasty Affords Symptom Relief for Patients With Multiple Sclerosis
Angioplasty Affords Symptom Relief for Patients With Multiple Sclerosis
Patients with multiple sclerosis (MS) who are treated for chronic cerebrospinal venous insufficiency with minimally invasive endovascular treatment may experience significant symptom relief and short-term improvement in their quality of life.
So say the authors of two studies presented at the Society of Interventional Radiology's 37th Annual Scientific Meeting in San Francisco. Results of those studies suggest that for many people with MS, minimally invasive interventional radiology treatments can provide effective palliative therapy.
In one study, researchers analyzed questionnaire responses from 192 patients with various forms of MS. The questionnaire reviewed key quality of life components, including changes in physical abilities, health perception, energy and fatigue, sexual function, emotional well-being, cognition, and pain, said Meridith J. Englander, MD, one of the study's co-authors.
More than 75% of those with relapsing remitting and primary progressive MS reported significant physical improvements. Mental health scores also improved in most of those studied.
A second study—a retrospective review of 105 angioplasty procedures—produced similarly encouraging results. Over half reported at least some symptomatic improvement; while 38% reported no improvements. Those with relapsing remitting MS reported the most favorable results.
For more details, please click here.


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DURHAM, N.C. — Santa Clara didn't leave the Eastern time zone with a victory over top-ranked Duke, but it might have proved to itself and others that it's ready to challenge for the West Coast Conference title.
The Broncos didn't back down from the Blue Devils, drawing praise from their Hall of Fame coach afterward, despite falling 90-77 at Cameron Indoor Stadium on Saturday.
"This was like a February ACC game," Duke coach Mike Krzyzewski said. "They're men. They're a man's team."
Santa Clara (11-3) weathered one Duke first-half run, turning an 11-point deficit into a four-point lead with 16:29 remaining. But the Blue Devils (12-0) responded with a 26-5 run that proved too much for the Broncos to overcome.
Duke won its 101st consecutive nonconference home game and dropped SCU to 0-12 all-time against No. 1-ranked teams.
Early on, SCU looked loose, scoring the first five points and hitting five of its first eight shots. Even after Duke got rolling with a 17-2 run, the Broncos didn't flinch, reclaiming the lead behind Kevin Foster, who scored 18 of his of 29 points in the first half.
"You've gotta come out with aggressiveness, you've gotta come out fighting, and you've gotta come out ready to play not scared, and our guys definitely did that," SCU coach Kerry Keating said.
Keating had experienced an upset win at Cameron before — nearly 20 years ago as an assistant at Wake Forest. That team included a lightly recruited freshman center named Tim Duncan.
Santa Clara, on paper, seemed to be overmatched. Despite matching Duke's win total, the Broncos ranked in the mid-200s in strength of schedule and 109th in the Ratings Percentage Index. Duke was No. 1 in the polls, No. 1 in RPI and No. 2 in strength of schedule, with victories over Kentucky, Louisville and Ohio State.
Duke also has Seth Curry, the brother of Warriors guard Stephen Curry, and Mason Plumlee, a senior center who averages 19.3 points and 11.5 rebounds. Curry scored 31 points, including 12 in the 26-5 run. Plumlee had 22 points and 13 rebounds.
Foster hit 5 of 11 shots from behind the 3-point arc, including one to cap a 16-4 run that put the Broncos ahead 30-29 and silenced the home crowd. That silence gave way to a chant of "SCU, SCU" from about 200 fans behind the Broncos' bench.
"I liked the fact that they had to adjust to us a little bit, because Kevin got it going early," Keating said.
Outside of Foster, the Broncos made just 4 of 16 shots from behind the arc, and SCU was outrebounded 40-28.
The Broncos, who got 17 points from Evan Roquemore and 10 apiece from Marc Trasolini and Raymond Cowles, open their WCC schedule Wednesday at home against USF. Saturday's experience — "There may not be a tougher place to play," Keating said — could serve as a springboard.
"I think we're going to be ready to compete for the top of our league," Roquemore said.


text:
Moderators: Timko, Fritz, Solty, Booter, Blake_T, Frank Delicious
iacas wrote: A 400-foot hole could easily be a par four if you had to throw 240 feet to the corner of a fairway, then turn 90° to the right and throw another 160'.
chainsmoker wrote:I do take exception to iacas saying that there is too much luck in disc golf. If you play courses that luck plays a major role I'm sorry but you are not playing good courses.
PMantle wrote:I do not understand what you are trying to convey.
keltik wrote:I'm gonna stand by the statement I made earlier. We need to just use the top two lines of Chuck's Chart and be done with it.
Frank Delicious wrote:There are a lot of bad courses out there.
PMantle wrote:That's no different than golf, and par and golf will never be separated. I think we agree on principals, but not on conclusions.
JR wrote:PMantle wrote:That's no different than golf, and par and golf will never be separated. I think we agree on principals, but not on conclusions.
I'm not a golfer and as such can't comment on how important it is there i was talking of disc golfers.
Frank i wrote in an earlier post that the way i see it par is only useful for up and coming players as a yardstick and i have no problem with it whatsoever.
veganray wrote:Par is a cryptid that is reputed to inhabit frolf holes in courses across the USA and, indeed, the world. It is similar to supposed lake monsters in Scotland and elsewhere, though its description varies from one account to the next. Popular interest and belief in par has varied since it was brought to the frolf world's attention in approximately 1964. Evidence of its existence is anecdotal and extremely flimsy, with minimal and much-disputed photographic material and pseudo-mathematical "proofs" of its existence.
The most common speculation among true believers is that par represents a vestige of a line of long-surviving red herrings of the genus chuckkennedia. The scientific community regards par as a modern-day myth, and explains methods of "calculating" or "measuring" it as a mix of hoaxes, extreme mathematical ignorance, and wishful thinking. Despite this, it remains one of the most famous - and perfect - examples of pseudoscience, and is revered by scores of frolfers the world over. The mythical creature has been affectionately referred to by the nickname "Three" for nearly 50 years.
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As promised we have added two more cards to our site for the holidays and three more will follow in the coming days. These cards really are the result of months of hard work and I am thrilled to finally be sharing them with you.
"Bright & Merry" was created for anyone spending the holidays in warmer climates or the southern hemisphere - or perhaps just wishes they would! It is set to a great bossa nova version of "Jingle Bells" on a beach and ... well, have a look for yourself to see the rest.
"Hanukkah" is our first card for the festival of lights. I am fond of the music I chose for it, which moved me. I think it perfectly sets the tone for a joyous celebration.
Let me know what you think!
eCards for Sunny Christmas and Hanukkah
at 8:59 AM
2 comments:
It's the first time I visit your blog and I'm just fascinated with such an artistic sensibility. Congratulations!ReplyDelete
These ecards, exactly like those I've just sent to a brunch of friends, reveal you as a fine taste woman.
For now I joined the list of your followers and I'm going to link you to my blog.
I keep viewing and viewing your ecards and can assure that I never get tired of it.
I promise I'll be back.
Thanks again
thanks for this!ReplyDelete
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Hi guys.
I have modified a version of opencart to include new tables and have modified the installer sql file. My queries run fine if I run them directly through the console but when I try to run the installer, it uses a PHPMyAdmin SQL dump and it fails complaining of a syntax error at "CREATE TABLE oc_address ( address_id" which is the first table below. I have racked my brains but cannot see any errors in the syntax, maybe I'm just tired! The strange thing is, the table which it seems to be complaining about is one of the ones I haven't modified.
The original software which I developed live on my hosting used MySql 5.3 but I am trying to get it onto localhost (with wampserver) which has v 5.5 installed, I don't know if this will make a difference?
Can anyone help me please?
-- phpMyAdmin SQL Dump-- version 3.2.2-- http://www.phpmyadmin.net---- Host: localhost-- Generation Time: Apr 06, 2010 at 10:14 PM-- Server version: 5.5.24-- PHP Version: 5.3.13
---- Database: OpenCart--
---- Table structure for table oc_address--
CREATE TABLE oc_address ( address_id int(11) NOT NULL AUTO_INCREMENT, customer_id int(11) NOT NULL, company varchar(32) COLLATE utf8_bin NOT NULL, firstname varchar(32) COLLATE utf8_bin NOT NULL DEFAULT '', lastname varchar(32) COLLATE utf8_bin NOT NULL DEFAULT '', address_1 varchar(128) COLLATE utf8_bin NOT NULL, address_2 varchar(128) COLLATE utf8_bin NOT NULL, postcode varchar(10) COLLATE utf8_bin NOT NULL DEFAULT '', city varchar(128) COLLATE utf8_bin NOT NULL, country_id int(11) NOT NULL DEFAULT '0', zone_id int(11) NOT NULL DEFAULT '0', PRIMARY KEY (address_id), KEY customer_id (customer_id)) ENGINE=MyISAM DEFAULT CHARSET=utf8 COLLATE=utf8_bin AUTO_INCREMENT=1;
Hi there,I can confirm that there's nothing wrong with the code you provide.I just tried running it on my machine (PHPmyAdmin (184.108.40.206) - Xampp (latest) - MySQL (5.0.90)) and it did what was expected.What is the error message you are getting?
Hi Pullo,
Thanks so much for trying the code, the error is ambiguous, just says you have an error in your mysql syntax near at "CREATE TABLE oc_addressat line 1 (
I don't really know what to do, like I said the original dump was running on MySql 5.3 and I understand that there are slight syntax differences between the different versions but I can't see anything wrong. I also don't have Wamp server configured incorrectly because it runs the original script just not the modified version.
The script is really very long, I didn't post the whole thing but if I delete a query the error just drops through to the next query so I'm a little puzzled. It seems to just keep finding errors on the first table creation of the script. Do you think it could be referring to an error later on in the script but telling me line 1 regardless?
I don't have any experience of mysql dump from phpMyAdmin as I have always queried directly from php, the opencart installer must be designed to do this by default. Do you have any idea what the code looks like to do a PhpMyAdmin mysql dump? I thought maybe I could find it and convert it to a straight mysql query from php?
thanks again
I will examine it more closely tomorrow.
including the whole error message rather than some of it will help others assist you with the problem.
hi there that is all of it, maybe i should enable error reporting on php too, perhaps it will give more information , this error is non bold text so i'm guessing it comes from mysql or phpmyadmin, have just run wamp server for the first time so haven't turned it on
Hi there,Just wanted to check if you found a solution to this.
Thanks for asking, there must have been some sort of syntax error somewhere but I didn't bother looking for it as the dump file was huge but what helped me was using PHPMyAdmin to create a dump file of my modified database and putting that file into opencart. There is an option under Export to create a dump file and you can either select structure, structure and data or just data, so I selected structure for a nice clean empty modified database
have a good day
Hi there silversurfer5150,
I'm glad you got it sorted. What you described would have been my next best guess anyway.
My day will be over within the hours (living in Germany and all that). Nonetheless, I'll do my best to sleep soundly


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* Peugeot wins support for early Aulnay wind-down
* Worker transfers follow reports of intimidation
* Renault seeking new labour deal in union talks
By Gilles Guillaume and Laurence Frost
* Peugeot wins support for early Aulnay wind-down
* Worker transfers follow reports of intimidation
* Renault seeking new labour deal in union talks
By Gilles Guillaume and Laurence Frost
PARIS, Feb 5 (Reuters) - PSA Peugeot Citroen won
staff agreement on Tuesday for an early wind-down of its doomed
Aulnay plant, as rival French carmaker Renault pressed
unions to sign a new national labour deal.
The moves by both French automakers, designed to address a
crisis of overcapacity and falling sales, have divided unions
and sparked protests and stoppages at sites around the country.
Peugeot, which has announced 8,000 job cuts and the planned
closure of the Aulnay plant on the northern outskirts of Paris
in 2014, presented plans to begin moving half of the factory's
3,000 workforce to another plant near the capital within days or
weeks - more than a year ahead of schedule.
The company said the early transfers were requested by
several unions following reported incidents of intimidation and
violence against workers defying the leftwing CGT's strike call.
"We are ready to carry them (the transfers) out as quickly
as possible for everyone's benefit," Peugeot spokesman
Jean-Baptiste Thomas said.
"Aulnay workers are under a lot of pressure," Thomas said.
"It's hard to put up with the kind of threats and assaults they
are suffering on a daily basis."
Peugeot, badly hit by Europe's auto sales slump, is
struggling to cut costs and lift sales in an effort to return to
profit in 2015. Renault is also wrestling with domestic
overcapacity as sales of its French-built models plunge in a
stricken European market.
The plans for an early departure of Aulnay workers were
backed by the centre-left CFTC, CGC and SIA unions at Tuesday's
works council and may be adopted on Feb. 15.
That would clear the way for Aulnay to shrink to one factory
shift from two, as 1,500 workers begin moving to the Poissy
plant west of Paris, which assembles the same Citroen C3 model.
"Our request is prompted by the situation at Aulnay," CFTC
official Franck Don said. "People are afraid and we have to do
something before anything more serious happens."
The transfer of workers will not lead to inventory
shortages, Peugeot said. Aulnay production is already at a
near-standstill because of the protests and a high absentee rate
among non-striking workers.
Despite the likely progress towards closing Aulnay,
Peugeot's broader restructuring faces possible delays resulting
from a successful court challenge by the CGT.
The union has also vowed to contest Renault's proposed
labour deal if the carmaker cuts corners on working-time changes
that may require cancellation of existing accords with 15
months' notice.
Besides 8,200 job cuts over three years, Renault is seeking
a pay freeze, longer working hours and flexibility measures
including the right to move workers between sites, which the CGT
has ruled out supporting.
"I don't see how any union could sign an agreement with such
damaging social consequences that also increases
inefficiencies," CGT spokesman Fabien Gache said.
"When there are fewer and fewer of us it gets harder to
maintain quality."
The French government, Renault's biggest shareholder with a
15 percent stake, expects the car maker to reach a deal on the
new labour agreement, an official source said.
Ministers had initially sided with auto workers and urged
Peugeot to scale back its restructuring plan announced last
July, but have since dropped their demands.
Industry Minister Arnaud Montebourg, one of the plan's most
vocal early critics, said it was "inevitable" that Aulnay would
close. "In any case we haven't found any other solution," he
said on RTL radio. "We can't see any other way around this."


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Longleat Safari and Adventure Park has unveiled a special 30 per cent discount on park Day Tickets throughout June to visitors living within the local area.
Running daily until June 30, the 'locals' Day Ticket gives unlimited entry to all rides, attractions and shows within the park and is an exclusive offer to the local community for people living within a 20 minute drive of Longleat.
Longleat CEO, Bob Montgomery, said: "We are keen to build stronger relationships with local residents. I hope this offer will be the first of many which show our intent and support for local community based initiatives.
"The promotion gives people living locally a more affordable day out and a chance to come and see the new attractions and features in the park.
"We're also set to launch a brand new ride within the next month called Rockin' Rhino for younger children, and hopefully it will be the local community which are the first to experience it and test it out.
"We also have the new walk-through Penguin Island and Stingray Bay areas within the Adventure Park which will provide other great experiences for visitors."
The new ticket offer is an addition to the local Annual Pass ticket for which a special discount is also available to people living within close proximity to Longleat.
Along with the new offer Longleat have recently announced the Pleasure Walk, which runs parallel to the Lodge Drive down to Longleat House, has re-opened again for free access to walkers and dogs.
Access to the Pleasure Walk will be from Horningsham close to the Bath Arms Hotel.
While the walk does not include entry to the main estate where the attractions are based, it will allow people to experience the stunning Capability Brown landscaped arboretum which has been part of the estate for more than 250 years.
Local people can also continue to enjoy the views from Heavens Gate, Shearwater and vast areas of woodland within the 9,000 acre estate. Plus the national Sustrans cycle route remains open for cyclists to enjoy.
The 30 per cent discount is valid on all types of the All In One Day Ticket and Deadly Day Ticket and is available from now until June 30.
For more information on the local offers visit www.longleat.co.uk/localresidents or email firstname.lastname@example.com


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Mhoon's grief-stricken family and loved ones, however, were still filled with pain from their loss – and during their turn to speak, they let Lewis know how they felt about the person Lewis had been and what he had done, not the person he could be.
The mother of Mhoon's children said they still ask where he is, and she reminded Lewis that the children will never know their father.
An aunt said she could barely make her remarks before telling Lewis, "Shame on you. You are not God. You can never be God. You should have let things be. Shame on you."
Mhoon's mother had even more pointed remarks about Lewis' negotiated sentence – which Judge Fran Gull accepted and rendered: 30 years, with 25 to be executed and five years suspended with five years' probation – saying, "This is a slap on the wrist. Things need to change in our society."
Gull, during her remarks, said the court empathized with both families for the loss of both men: Mhoon's death and Lewis' subsequent incarceration.
Lewis was given credit for 248 days served; with state policy mandating a day served equals two days of a sentence with good behavior, it is possible Lewis could be freed in roughly 10 years.
He pleaded guilty Jan. 16 to a single count of voluntary manslaughter after originally being charged with murder in the death of Mhoon, according to documents filed in Allen Superior Court. Lewis had ridden to the store with two other men June 8, according to the documents. When one of the men became involved in a fistfight with Mhoon inside the store, Lewis allegedly came in and shot Mhoon, police said in the documents.
Witnesses told police that Lewis continued to shoot as Mhoon fled the store, firing between five and seven shots, the documents said. Two witnesses later contacted police and identified Lewis, the documents said. Mhoon died at the scene.
Under state law, the minimum sentence for voluntary manslaughter with a deadly weapon, a Class A felony, is 20 years in prison.


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10 Best of the 2013 Detroit Auto Show
Auburn, Ind.
It's hard to believe that monster trucks have been around for more than three decades. What began as one giant 4WD pickup truck named Bigfoot, created by Bob Chandler, has evolved into a competitive industry that draws hundreds of thousands of people to events each year. The trucks themselves have certainly changed since Bigfoot crushed its first car, but many of the monster trucks that garnered some fame and excitement along the way were thought to have been lost.
No longer. Jeff Cook, who built and drove the War Wagon monster trucks from the 1990s, decided the world needed a museum to archive the history of monster trucks. The museum's revolving collection has housed some of the most interesting trucks the sport has seen—including the very first Bigfoot, Beast, Goliath, and lots more.
Nashville, Tenn.
The Lane Motor Museum has one of our favorite quirky car collections. The Nashville museum features more than 45 different vehicle marques from around the world, including countries not necessarily known for their auto industries, such as Austria, Czechoslovakia, and the Netherlands. Ever seen a rear-engined V-8 Tata from the late 1970s? The museum's 1978 T-613 is one of a dozen cars from that Czech manufacturer.
Lane's collection has a good selection of military vehicles from around the world too. And the museum's pieces range in size from the smallest microcars to a giant 1959 LARC-LX—an amphibious cargo hauler that stands almost 20 feet tall, rides on 9-foot tall tires, and weighs 194,000 pounds.
The Top Tech of the 2013 Detroit Auto Show


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Events in the next 7 days
June 25, 2011 - December 7, 2014
Special Exhibit
Picturing Science
This exhibition features more than 20 sets of large-format images that showcase the wide range of research being conducted at the Museum as well as how various optical tools are used in scientific studies.
Through January 5, 2014
Special Exhibit
Whales: Giants of the Deep
Whales: Giants of the Deep brings visitors closer than ever to some of the mightiest, most massive, and mysterious mammals on Earth.
© Brandon Cole, Romeo/V&W, SeaPics.com
Saturday, April 13
Members Only Programs
Sold Out
Members Only
Members' Trip To Brooklyn Grange
Discover a farming system right over our heads, at the Brooklyn Grange rooftop organic farm in Long Island City.


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My son wants to become an architect and I was looking into schools and our local vocational school offers a drafting/mechanical engineering program. Is it worth me sending him thru this program now or should he just wait until college? He has been talking about being a mechanical engineer or architect for about 5 years now. He is currently a freshman in high school.
Thank you.
This has nothing to do with architecture. A drafting tech may never work for an architect, and probably won't if its a specialized mechanical engineering degree. Drafting standards are very different based on what kind of drafting you're doing - mechanical, architectural, civil, electrical, etc. Not just that, but schools don't really make you good a good draftsperson. 99% of his real world skill will come from experience picked up in offices during internships, etc. The basics will come from school.
Except for someone with life experience relevant to mechanical drafting no one here can give you any informed advice above anyone else.
I would highly suggest taking any sort of drafting or design class in high school before making the choice to study architecture in college. At best, it will prepare your son for the stress and demands of a design course. At the very least, he'll learn how to draw, and if he decides to study archiecture or engineering in college, he'll be at an advantage. I went to school with people who didn't know how to use a scale or how to and draft. I knew that already because I took classes in high school. I actually ended up showing a lot of people how to use the drafting tools and later on CAD.
there's a big difference between what an engineer might have to draw and what an architect might have to draw, so its hard to address the questions of someone who might want to be one or the other.
as a teacher, there's nothing worse than seeing the 'architecture' drawings someone did in high school and having to shrug your shoulders and explain all the reasons why they are not very good drawings, even though whats on the page looks like what everyone thinks a house looks like. From what I've seen, local vocational type programs are more interested in producing students who are 'certified' in the use of a specific cad program - which in no way means that they know how to draft. By drafting I mean that they know how to collapse 3 dimensions onto a flat page and how to flip around and intersect and cut that information. Knowing how to do these things becomes less critical when the software can do it all for you, so I'm even more suspicious of someone learning how to 'draft' when taking what is essentially a vocational software training class. Is your local program better? How can we tell? Its pretty doubtful such a program is a place to get any design experience or to get a sense of the stress/demands of college courses - unless its a really good program. I also dont believe that work experience will teach someone how to draft, but it will teach them what needs to get drawn for different sets and situations - thats not drafting though - in my opinion.
to happily cut myself short here, i would say that the sooner and better acquainted someone gets with software, thats all for the better. and the sooner one might be able to differentiate between their desire to be an architect or engineer, thats also for the better. But im very suspicious of any high school design action and equally suspicous of any high school drafting experience - but thats just from the messes I've seen. So yes, the sooner the better, the more to build upon the better, but there is a real qualitative difference between software training and being trained into a discipline.
For Pete's sake, people, the man is asking about a drafting program in high school.
Yes, your son would greatly benefit from this kind of exposure to drawing and learning spatial relationships at this early stage. (Some of the well-intended comments above rightly point out that such a program is not architectural; very true. And if the choice is between an architecture curriculum and one in mechanical engineering, then by all means choose the architectural one. But most high schools don't have this choice, and a good program in an allied field --one that trains youngsters in space, precision, drawing, etcetera-- could be very beneficial.)
My recommendation would align with my colleagues above if the student in question were applying at the college level, but he's not. He's what, 14? This is a great opportunity for him to start learning some (not all, but some) of the basic skills needed in architectural training. To this, he might take whatever opportunities available to learn architectural software / techniques. Also, visiting local architects' offices and talking to practicitioners is another good way to learn more about the field.
Good luck.
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SpearsNBAYahoo Marc J. Spears
RIP @ESCALADE53. Good friend I met in Louisville days. Told me 2 days ago that he was proud of me. Sad news.
sad news, Was a street ball legend with and 1InsideHoops InsideHoops.com
Damn. Mark Jackson's brother Troy, aka streetballer Escalade, passed away. Beyond sad. Everyone loved the guy.


text:
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December 10, 2011 BY Aaron Hope
United Arrows' Beauty & Youth label has worked in concert with Vans quite a few times over the past several years, but now they're branching out to get up with another US-born brand who's known for their numerous Japanese collaborators. The Beauty & Youth x New Balance CM1700 brings in Japan's Briefing luggage company to add two bags to the package, one that looks like a laptop case plus a fanny pack that makes you wonder if there's enough 'no nonsense' in common between NB and 'Stone Cold' Steve Austin to ever spark such a tag team. You won't have to wrestle with your wardrobe to find a variety of suitable matches for these NB 1700s, though, because like many of the brand's best loved classics, these are downright stunning in the go-to premium grey suede. B&Y adds a red lace to match the bags' details, and the whole set should be available at United Arrows retail spots come January.
Filed under: Asia Exclusive Collaboration Gear Japanese Brands New Balance Upcoming Sneakers


text: Increased Efficiencies Supports Company's Focus on New Product Development Foster Farms Dairy has announced it is adding fluid milk and orange juice production to its Modesto plant which will result in approximately 50 new jobs for the area. The addition will improve capabilities at the all-purpose plant while leveraging resources and taking advantage of Modesto's central location for both milk production and west coast consumer markets. As part of the Modesto expansion, the company will shift milk and orange juice production from its plant in Fresno. Foster Farms Dairy has been updating and modernizing its Kansas Avenue plant in recent years to process a variety of dairy products including fluid milk, cultured products and ice cream. It manufactures milk, juices, ice cream, sour cream, cottage cheese and specialty dry powders and mixes. "This expansion is key to our growth as a one-stop dairy products supplier and the premier frozen dairy dessert provider on the west coast," said Jeff Foster, chief executive officer. He added, "We have put great focus on developing a fully-integrated dairy program with an array of new consumer products and innovative offerings in recent years and this will enable us to continue that effort." Among the latest product offerings being produced at the Modesto plant includes half-gallon milk jugs, single-serving milk containers as well as being the first processor on the West Coast to offer new milk products such as Dairy Balance with Probiotics which provides the essential proteins, vitamin D and calcium of regular milk with the added benefit of probiotics to help support a person's digestive and immune health. "We are constantly listening to our customers to anticipate their needs and as a result, our new product offerings, particularly in the frozen dessert category are being extremely well-received," said Foster. He added, "Our success includes exciting new ice cream flavors such as Cherry Chocolate Chunk, new packaging sizes such as our 3.6 ounce on-the-go items and a variety of frozen novelties that include cones, bars, sandwiches and cups." In recent years, the company has expanded its business through acquisitions of ice cream plants in Sacramento and Salem, Oregon. In 2007, it purchased the popular Crystal Cream and Butter Company and added the Crystal brand to its product offerings. Two years later, the company purchased Humboldt Creamery, a producer of organic and conventional dairy products based in Eureka. About Foster Farms Dairy Foster Farms Dairy is family owned and has been operating in California since 1941. It employs more than 1,100 people throughout California and Oregon while processing more than 130 million gallons of processed products annually. Today the company is led by Jeff Foster, grandson of the founders. Seventy years after its founding, Foster Farms Dairy is still committed to the same principals as founders Max and Verda were when they started the business: Honesty, People, Quality, Service and Excellence. Producer of a full line of products including milk, cottage cheese, sour cream, ice cream, and butter, the Dairy remains committed to animal welfare and environmental sustainability. Producer of a variety of dairy brands including Crystal, Humboldt Creamery, Deluxe, Vitafreeze and now Dairy Balance, Foster Farms Dairy is proud of its long history of providing customers the freshest, local dairy products possible. For more information about Foster Farms Dairy visit www.FosterFarmsDairy.com or call Foster Farms Dairy directly at 888-316-6064. 08.18.2011


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Fairfax County Taxicab Rates Increase
Fairfax County Office of Public
12000 Government Center Parkway, Suite 551
Fairfax, VA 22035-0065
July 19, 2005
Fairfax County Taxicab Rates Increase
The Board of Supervisors has adopted a request from the Fairfax County taxicab industry to raise rates. Beginning Wednesday, July 20, the drop, distance and waiting time rates charged by Fairfax County taxicabs will increase. The rate of an average fare for an 11-mile trip will go up by 11.3 percent. The following changes will be implemented:
- The initial drop charge will change from $2.25 for the first one-quarter mile to $2.75 for the first one-fifth mile.
- The succeeding mileage charge will change from $1.60 per mile to $1.75 per mile (the increment charge changes from 40 cents per one-quarter mile to 35 cents per one-fifth mile).
- The waiting time charge will change from $18 per hour to $21 per hour (the increment charge changes from 40 cents per 80 seconds to 35 cents per 60 seconds).
The rate increases support the rising costs of providing quality taxicab services, the cost of living for taxicab drivers and rising gasoline prices. The increases also will help in recruiting and retaining qualified, experienced drivers.
The last permanent taxicab fare increase in Fairfax County was approved in February 2001. At that time, the board approved an increase of 7.2 percent on an average fare. The rise in fares was justified on the basis of increases in the cost of living and in gasoline prices.
On July 12, 2004, in response to rapidly increasing prices of gasoline, the board approved an emergency 50-cent gas surcharge. This surcharge on taxicab rates was in effect from July 19, 2004, until Dec. 31, 2004. During the period of the surcharge, gas prices averaged from $1.81 to $2.01 per gallon.
For more information, visit the Consumer Protection Division Web page at www.fairfaxcounty.gov/consumer.htm or call the Department of Cable Communications and Consumer Protection at 703-222-8435, TTY 711.
Fairfax County is committed to a policy of nondiscrimination in all county programs, services and activities and will provide reasonable accommodations upon request. To request special accommodations, call 703-324-3187, TTY 703-324-2935. Please allow five working days in advance of events in order to make the necessary arrangements.


text:
You know how retailers are battling it out over the few dollars consumers are willing to spend? It's no different in the nonprofit world. Merely grabbing a donor's attention isn't enough. We have to make a solid argument for why our cause is the one worthy of your hard-to-part-with dollar.
711 Third Avenue - Suite 700 | New York, NY 10017 | 212-949-4800 | 212-949-4936 (Development)
The Children's Aid Society is registered as a 501(c)(3) non-profit organization


text:
Goldman Downgraded
O'Connor downgraded Goldman Sachs ( GS) to a "Hold" rating from a "Buy" rating, saying that the shares were up 50% since August, and that although the shares had lagged Bank of America ( BAC), Citigroup ( C) and Morgan Stanley ( MS) "a bit," they had outperformed JPMorgan Chase ( JPM) "by 1600 bps." Goldman reported fourth-quarter earnings of available to common shareholders of $2.833 billion, or $5.60 a share, increasing from $1.458 billion, or $2.85 a share in the third quarter, and $978 million, or $1.84 a share, in the fourth quarter of 2011, with large increases in both debt and equity underwriting revenue; continued strength in institutional client servicing revenue, which was up 4% sequentially and 42% year-over-year to $4.342 billion; and increases of 9% sequentially and 126% year-over-year in investing and lending revenue, to $1.973 billion. O'Connor raised his 2012 earnings estimate for Goldman Sachs to $13.24 from $12.26 and raised his 2014 EPS estimate to $14.40 from $14.00 and said that the stock was now trading "in line" with his 2013 earnings estimate and "a 15-20% premium" to his estimates for 2014 and 2015. He added that "GS also trades at a 15-20% premium on tangible book vs. peers," and that "one could argue both more regulatory uncertainty on earnings (see below) and less of a cost savings story from here." The following are the five large-cap bank stocks with "Buy" recommendations from O'Connor, ranked by descending forward ratios of price to consensus 2014 earnings estimates:


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UNBLEMISH Regimen
UNBLEMISH Regimen
Break the Breakout Cycle
after two weeks
after four weeks
after six weeks
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Posted 6 years ago
(1 item)
A pipe given to my great granddaddy George Gipson Gentry Waddill by the old Native American Indian Chief Geronimo around 1886 in Schulenburg, Texas. "Gip" Waddill or "3G" fought for the South in the Civil War and was assigned to the New Mexico area where he met and befriended the old Chief. When Geronimo finally surrendered to the Union they stayed overnight in Schulenburg and great granddad Waddill shared his tobacco with him and his men. When they parted the old chief gave him his pipe. It's been in my family over a hundred years.
L. K. Waddill ~ Mason, Texas


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Local authorities are to be given more power to control the number of betting shops opening in their area as part of a government review of gambling policy.
Gambling firms who want to open up new betting shops on the high street may find they are stopped from doing so under new plans to give local authorities more control over the make-up of their high streets.
Bookies who want to open new shops will have to submit a planning application and local councils will be able to refuse applications and stop new betting shops opening in their area.
The Department for Culture, Media and Sport (DCMS) said local communities up and down the country had expressed concerns about the clustering of betting shops on some high streets.
The current system classes a betting shop in the same category as a bank or estate agent, meaning they can open without the need for a planning application when a premises becomes vacant.
The changes will mean that local councils can scrutinise the applications and refuse them where there are grounds to do so.
The Government said it was also looking at controls on gambling advertising, including requiring betting firms to show how they were complying with social responsibility codes when they applied for a license, ensuring that controls on gambling advertising provided enough protection and working with the industry to explore initiatives to help prevent under-age access to gambling.
And it has set out plans to improve protections for players on Fixed Odds Betting Terminals (FOBTs), including making those who want to bet more than £50 in one play to pay over the counter, meaning that they have to interact with staff.
Other measures for FOBTs include changing the rules so that users must be presented with a choice to set limits on how much they want to spend and how long they want to play for, regular warning messages and pauses in play to encourage players to be more aware of their gambling, and a strengthened voluntary self-exclusion system so that players can make a single request to be banned from betting shops.
Planning minister Nick Boles said: "This Government is taking action to support healthy and vibrant local high streets.
"This is part of a wider set of measures designed to get empty and redundant buildings back into productive use and make it easier for valued town centre businesses like shops, banks and cafes to open new premises, while giving councils greater powers to tackle the harm to local amenity caused by a concentration of particular uses."
Communities minister Stephen Williams said: " Across the country many people are concerned about the explosion in the number of betting shops in some high streets.
"The Coalition Government is determined to build a stronger economy and a fairer society with healthy and diverse high streets that aren't dominated by betting shops, this is why we are now giving councils tough new powers to prevent the proliferation of betting shops in their area."
Hackney mayor Jules Pipe said: "This announcement represents a real victory for local government and demonstrates what councils can achieve when they unite for a cause.
"Hackney Council, along with authorities across the country, has long been calling on government to give us the tools to tackle the blight of bookies in our high streets.
"At last, ministers have listened to the overwhelming weight of public and council opinion against the current betting shop free-for-all.
"We will now look into the detail of these proposals.
"If, as it appears, they could deliver the meaningful change to planning law which we've been campaigning for we will push for any new legislation to be brought in as soon as possible.
"Such changes cannot come soon enough and it's crucial councils remain united during the consultation process as we should be in no doubt the powerful gambling lobby will do its best to water down these proposals."
DCMS Minister Helen Grant said: "We want there to be a gambling sector that is vibrant and responsible. The Government wants to make sure the industry is putting player protection and social responsibility at the heart of their businesses."
Salvation Army spokesman Gareth Wallace said: " Today's announcement of a voluntary ceiling of £50 for fixed-odds betting machines is welcome but we believe a radical cut to no more than £10 per stake is necessary to stop problem gamblers from losing life-altering amounts of money. The proposal for account-based or over-the-counter betting could be beneficial because this enables breaks in play.
"Fixed-odds betting terminals, which are popping up in betting shops across the country, are one of the most addictive forms of gambling and enable people to bet £100 every 20 seconds.
"We welcome the Government's promise to look at measures which include players being able to pre-set limits on time and money per gambling session before they start. Any measures that remind players of how quickly they are losing money could help reduce problem gambling.
"Although Eric Pickles has announced that his department will consult on providing greater powers for local communities, we believe that a new planning category is necessary to ensure betting shops are no longer counted alongside financial services such as banks.
"We also call from more powers to reduce clustering of betting shops in high streets, further research into FOBT machines, including their density, location and social impact, and more government-funded help to treat people with gambling additions."
Local Government Association licensing spokesman Tony Page said: " Communities and councils have consistently called for tougher powers to address problems caused by the proliferation of betting shops and FOBTs so we are pleased the Government has listened to our concerns and is taking action.
"We need to understand the detail of how these proposals will work in practice and when they will take effect, but this could be a significant step in the right direction.
"Councils are not anti-bookies, and understand that betting shops can be an important part of local communities that create jobs for local people.
"However, we know how concerned people are by clusters of betting shops taking over their local high street, and there are also fears that people losing money through FOBTs are turning to payday lenders and loan sharks to pay off debts or fund their gambling.
"Betting industry firms like William Hill and BetFred have come out in support of tougher powers for councils and we will use our new Betting Commission to work with the betting shops to consider these new proposals to make sure they are workable. The betting industry needs to respect government's intentions and the concerns of local residents, and respond appropriately."
Betting company Ladbrokes said the announcement was the "latest in a series of measures which will impact the betting industry, hit shop profitability and threaten jobs".
It added that further shop closures remained inevitable.
The company said: "Ladbrokes is fully committed to operating to the highest standards in social responsibility and we note today's announcement from Government for the industry to do more to promote responsible gambling and protect the vulnerable.
"We intend to play a full role in the consultation process but now call upon the Government to give the industry a period of stability to allow us to deliver a service to our customers, invest in our business and minimise the impact on our employees."
The Association of British Bookmakers (ABB) said today's announcement would restrict growth in the sector, and meant hundreds of shops and thousands of jobs were now at risk.
ABB chief executive Dirk Vennix said: "The proposed changes to the way customers are able to stake more than £50 will impose extra costs on the industry whilst there is no evidence to show that restricting B2 stakes (a maximum of £100) will do anything to minimise problem gambling.
"Limiting access to one product just means the vast majority of responsible gamblers will be inconvenienced and problem gamblers will gamble on other products.
"We also want to work constructively with the Government and the Gambling Commission to keep problem gambling at the record low levels because we share the same objective - that one problem gambler is one too many. That's why we want to work with all parties to build the best possible harm prevention framework.
"The industry's new Code of Conduct for Player Protection has already had a significant impact with breaks in play, increased customer interaction and more self-exclusions.
"We look forward to seeing the results of the independent research into problem gambling because regulatory decisions have to be based on empirical evidence. We will await the Licence Conditions and Codes of Practice consultation, and hope this is based on a proper regulatory impact assessment."
Shadow sports minister Clive Efford said: " After months of dithering by David Cameron, it is disappointing today's proposals appear not to have been properly thought through.
"The Government's new £50 limit for FOBTs is a sham. Only 7% of plays on FOBTs are above £50 so this will have little impact and players will still be able to stake up to £100 on a single spin by seeking permission from betting shop staff.
"For more than two years Labour has been calling for local authorities to be given powers to deal with betting shop clustering and to reduce the number of FOBTs where local people demand action. The government is performing only a partial u-turn on planning powers but is doing nothing for those local authorities that already have problems.
"Whilst the Prime Minister is now accepting there is a problem, the Chancellor is busy making a £90 million tax grab on FOBT profits, making Cameron and Osborne the biggest FOBT addicts of all."


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Twins still working on deal sending Albers to Korea
MINNEAPOLIS -- Twins general manager Terry Ryan confirmed Friday that he's trying to facilitate a move for left-hander Andrew Albers to the Korean Baseball Organization.
The Twins have yet to reach an official agreement with the Hanwha Eagles, but it could come as soon as this weekend. SportsNet Canada reported the left-hander would make roughly $1 million to pitch in Korea next year and would be a free agent after the season.
Albers, 28, was the club's Minor League Pitcher of the Year in 2013 after posting a 2.86 ERA in 22 starts with Triple-A Rochester. He also posted a 4.05 ERA in 10 starts with Minnesota. But with the Twins signing right-handers Ricky Nolasco, Phil Hughes and Mike Pelfrey this offseason, Albers was a long shot to make the rotation out of Spring Training.
So Albers has been weighing his options and believes a move to South Korea could be good for him. But he said it's not an easy decision because the Twins were the organization that took a chance on him in 2012, when they signed him to a Minor League deal after he pitched for a year in the independent Can-Am League.
"It's an awfully tough decision because the Twins have been so great to me and have given me so many opportunities," Albers said. "They took a chance on me when nobody else would, so it makes it tough on me. But on the other hand, this would be a great opportunity for me."
Albers, who attended the Diamond Awards on Thursday and is at TwinsFest this weekend, added some paperwork still has to be completed before the move is official.
"Right now, it's in the process of possibly happening," Albers said. "Nothing has been finalized yet. There's a Korean team that has expressed some interest. They're talking to the Twins, but I'm not sure where they're at at this point. But we'll find out in the near future."
Rhett Bollinger is a reporter for MLB.com. Read his blog, Bollinger Beat, and follow him on Twitter @RhettBollinger. This story was not subject to the approval of Major League Baseball or its clubs.


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The Kentucky Chapter of the Crohn's and Colitis Foundation of America hosted the first inaugural Cupcakes and Cocktails event at Eclipse Bank on Sept. 22 to raise awareness and funds to support research for Crohn's and colitis.
The fete included a signature cocktail sponsored by Brown-Forman and four local bakeries competing for Best Presentation and Best Tasting cupcakes. Kelly K with 99.7 WDJX emceed the event and served as a celebrity judge in the cupcake contest. James Brown from Brown Bakery in Lexington; Angie Fenton, managing editor of The Voice-Tribune; and Steve Stratton, CEO of Eclipse Bank, also served as judges.
In addition to the contest, guests bid on an exclusive silent auction, enjoyed live music and savored cupcakes and light hors d'oeuvres.
Photos by LIAM SPRADLIN | Contributing Photographer


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Enthusiasm is building for The Packer's inaugural Midwest Produce Conference & Expo, set for Aug. 13-15 in Chicago.
"Our regional show concept is proving to be a very popular format for buyers and sellers to connect in a cost-effective, intimate, and time-sensitive setting," said Shannon Shuman, The Packer's publisher. "Midwest Produce Expo has had a very enthusiastic response and The Packer is excited to provide a forum for Midwest buyers and vendors to collaborate on issues specific to this diverse region."
Exhibitors at the show look forward to meeting with customers (and potential customers) in a more intimate, relaxed environment.
The Midwest show, slated for Aug. 13-15 in Chicago, is a regional trade show on the order of shows put on by the Southeast Produce Council, the New England Produce Council and, most recently, the New York Produce Show and Conference.
Midwest Produce will include a five-hour exposition; programs on consumer trends, nonprofits and locavores; networking receptions; retail tours; and a golf outing.
Selah, Wash.-based Rainier Fruit Co., which is scheduled to be an exhibitor at Midwest Produce, also has exhibited at the New York and New England shows. Contacts made there have generated new leads that generated new business for Rainier, said Suzanne Wolter, marketing director.
One advantage of the regional shows vs. larger industry shows, Wolter said, is the chance to meet with buyers who don't attend the big shows like the Produce Marketing Association's Fresh Summit.
Also, the quality of those meetings can be much better.
"It's much more relaxing compared to the really large shows," Wolter said. "People take the time to talk with you for a little while, and there aren't as many demands on your time."
As for Midwest Produce in particular, Wolter is hoping to meet buyers from independent chains in the Upper Midwest who don't make the trek to Fresh Summit and the United Fresh Expo.
With the devastating freeze in Michigan, and a big crop expected out of Washington, Rainier could find a willing audience in Chicago for Washington apples, Wolter said.
Neil Galone, vice president of sales and marketing for Orange Cove, Calif.-based Booth Ranches LLC, another Midwest Produce exhibitor, began attending the New England, Southeast and New York regional shows about two years ago.
Fresh Summit remains the most important annual show in the industry, Galone said, but the regional shows definitely have their advantages.
"Fresh Summit is so big, it's hard to accomplish any business," he said. "And we found that in the more intimate setting, we, as a medium-sized company, don't get overshadowed."
Booth Ranches has specific growth plans for the Midwest, and Galone hopes the Midwest Produce Conference & Expo will help expedite those plans.
At larger shows, it's hard to stop moving, said Mike Angelo, director of national sales for Calavo Growers, Santa Paula, Calif., also exhibiting at The Packer's expo.
"You're there, but you spend most of your time just getting around the show," he said. "The regional shows give us a chance to be more one-on-one with people."
A show in Chicago is perfect for Calavo, which is looking to expand its presence in the region, Angelo said.
"We've always had pretty good relationships there," he said. "And some of the smaller independents who have grown are now becoming attractive as customers for us."
Calavo customers in the Upper Midwest have said they're excited about attending the show, Angelo said.


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A Phase III, Randomized, Double-Blind, Multicentre Study to Evaluate the Safety and Efficacy of 1592U89 in Patients With AIDS Dementia Complex
This study has been completed.
Glaxo Wellcome
Information provided by:
NIH AIDS Clinical Trials Information Service
ClinicalTrials.gov Identifier:
First received: November 2, 1999
Last updated: June 23, 2005
Last verified: November 1998
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Detailed Description:
To evaluate the benefit of adding 1592U89 to current antiretroviral therapies for AIDS dementia complex and to assess the safety and tolerance of the treatment regimens.
|AIDS Dementia Complex HIV Infections
|Drug: Abacavir sulfate
|Phase 3
|Study Type:
|Study Design:
|Masking: Double
Primary Purpose: Treatment
|Official Title:
|A Phase III, Randomized, Double-Blind, Multicentre Study to Evaluate the Safety and Efficacy of 1592U89 in Patients With AIDS Dementia Complex
Resource links provided by NLM:
MedlinePlus related topics: Dementia HIV/AIDS
Drug Information available for: Abacavir Abacavir sulfateU.S. FDA Resources
Further study details as provided by NIH AIDS Clinical Trials Information Service:
Patients must be on stable antiretroviral treatment for at least 6 weeks prior to study entry and will then be stratified depending on whether their regimen contains zidovudine (ZDV). Each stratum will be randomized separately to receive 1592U89 or placebo for 12 weeks. For the subsequent 40 weeks, open-label 1592U89 will be offered.
|Ages Eligible for Study:
|18 Years to 65 Years (Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria
Patients must have:
- Documented HIV infection.
- Evidence of HIV - associated dementia.
- Been on stable antiretroviral treatment for a minimum of 6 weeks prior to study entry.
Exclusion Criteria
Co-existing Condition:
Patients with any of the following symptoms or conditions are excluded:
- Debilitated as a result of their HIV disease, associated illness or therapies who the investigator determines will not be able to complete the 12 week randomized dosing period.
- Memorial Sloan-Kettering (MSK) score of >= 3 for dementia.
- Confounding neurological diseases which may interfere with interpretation of neurological and neurophysical assessments.
- Malabsorption syndrome or other gastrointestinal dysfunction which renders them unable to take oral medication.
- Chronic diseases such as diabetes, congestive heart failure, cardiomyopathy, other cardiac dysfunctions, etc., which in the investigator's opinion would compromise the safety of the patient.
- Symptomatic AIDS-defining opportunistic infection not responsive to therapy.
Concurrent Medication:
- Treatment with cytotoxic chemotherapeutic agents within the first 12 weeks of the study.
- Treatment with nerve growth factor within the first 12 weeks of study.
- The use of narcotic analgesics, sedatives, benzodiazepines, antidepressants, anti-psychotic agents and other psychoactive drugs which would interfere with the assessment of the neurological and neurophysical status of the patient.
- Use of stavudine (d4T) during the first 12 weeks of the study.
- Immunomodulating agents (except GM/G-CSF or epoietin).
- Psychoactive drugs (at the investigator's discretion).
Concurrent Treatment:
- Treatment with radiation therapy within the first 12 weeks of the study.
- With the exception of local treatment for Kaposi's sarcoma.
Patients with any of the following prior conditions are excluded:
- Previous neurological disease unrelated to HIV infection.
- History of clinically apparent hepatitis within the last 6 months.
- History of clinically apparent pancreatitis in the last 6 months.
Prior Medication:
- Treatment with cytotoxic chemotherapeutic agents within 1 month of entry.
- Participation in investigational antiretroviral trials within the past 3 months.
- HIV vaccine within the past 3 months.
- Treatment with immunomodulating agents such as systemic corticosteroids, interleukins, thalidomide, anticytokine agents, anti-oxidants or interferons within 1 month of study entry.
- Nerve growth factor.
Prior Treatment:
- Treatment with radiation therapy within 1 month of entry.
- With the exception of local treatment for Kaposi's sarcoma.
Risk Behavior:
Current alcohol or illicit drug use which may interfere with the patient's ability to comply with the study protocol.
- Stable antiretroviral treatment that has been ongoing for a minimum of 6 weeks prior to study entry, may or may not include ZDV.
- Stable antiretroviral treatment for a minimum of 6 weeks prior to study entry.
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00002163
Please refer to this study by its ClinicalTrials.gov identifier: NCT00002163
|United States, California
|HIV Neurobehavioral Research Ctr
|San Diego, California, United States, 92103
|San Francisco Gen Hosp
|San Francisco, California, United States, 94110
|United States, Maryland
|Johns Hopkins Univ School of Medicine
|Baltimore, Maryland, United States, 21287
|United States, Missouri
|Washington Univ Med Ctr
|St Louis, Missouri, United States, 63110
|United States, New York
|Mount Sinai Med Ctr
|New York, New York, United States, 10029
|Columbia Univ / Sergievsky Ctr
|New York, New York, United States, 10032
|United States, North Carolina
|Univ of North Carolina School of Medicine
|Chapel Hill, North Carolina, United States, 27599
|Canada, Manitoba
|Univ of Manitoba / Faculty of Medicine
|Winnipeg, Manitoba, Canada
|Canada, Ontario
|Wellesley Hosp
|Toronto, Ontario, Canada
Sponsors and Collaborators
Glaxo Wellcome
More Information
Keywords provided by NIH AIDS Clinical Trials Information Service:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on September 21, 2017
Lanier ER, Sturge G, McClernon D, Brown S, Halman M, Sacktor N, McArthur J, Atkinson JH, Clifford D, Price RW, Simpson D, Torres G, Catalan J, Marder K, Power C, Hall C, Romero C, Brew B. HIV-1 reverse transcriptase sequence in plasma and cerebrospinal fluid of patients with AIDS dementia complex treated with Abacavir. AIDS. 2001 Apr 13;15(6):747-51.
|ClinicalTrials.gov Identifier:
|NCT00002163 History of Changes
|Other Study ID Numbers:
|Study First Received:
|November 2, 1999
|Last Updated:
|June 23, 2005
Keywords provided by NIH AIDS Clinical Trials Information Service:
Acquired Immunodeficiency Syndrome
AIDS Dementia Complex
Antiviral Agents
Additional relevant MeSH terms:
HIV Infections
AIDS Dementia Complex
Lentivirus Infections
Retroviridae Infections
RNA Virus Infections
Virus Diseases
Sexually Transmitted Diseases, Viral
Sexually Transmitted Diseases
Immunologic Deficiency Syndromes
Immune System Diseases
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Neurocognitive Disorders
Mental Disorders
Reverse Transcriptase Inhibitors
Nucleic Acid Synthesis Inhibitors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Anti-Retroviral Agents
Antiviral Agents
Anti-Infective Agents
Anti-HIV Agents
ClinicalTrials.gov processed this record on September 21, 2017


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Drew feels healthy, ready to help Red Sox
FORT MYERS, Fla. -- If another season is drawing near, the Red Sox must be breaking in a new shortstop. The revolving door that hasn't stopped since Nomar Garciaparra was traded on July 31, 2004, continues into another year, as veteran Stephen Drew is the latest to join the carousel.
With the same No. 7 his older brother J.D. wore and an eerily similar voice, Drew is eager to get started in the next chapter of his career.
Drew is on a one-year contract, which means the Red Sox will probably have -- yep -- another new shortstop in 2014. The good news is that the pipeline is suddenly stocked, as Jose Iglesias, Xander Bogaerts and Deven Marrero all aim to be the team's shortstop of the future.
In other words, Drew could well be a placeholder.
"Right now, I'm just going to focus on this year," Drew said. "I'm really excited to be here and hopefully I put up a good year. Every year you want to come in and talk about getting to the World Series. Hopefully we can get there."
Drew is eager to rebound from his subpar 2012 season, when he was still recovering from a broken right ankle suffered in a fierce collision in 2011.
"I feel good," Drew said. "After that injury, an unfortunate accident, it was a long process getting back. I feel really good. All the hard work I put in and the preparation coming in this year, I hope it pays off. I really did put a lot of work into it. I'm just ready to get going and see how it goes."


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Bitauto: Optimistic On Auto Advertising Spend; Oppenheimer Raises Price Target
Chinese Internet companies are now cautiously optimistic on advertising, expecting a rebound in the fourth quarter this year and next.
Oppenheimer analyst Andy Yeung raised his price target on Bitauto (BITA) from $15 to $20 to reflect improved sentiments from automotive advertisers:
Bitauto management was optimistic about sustaining 30%+ growth over the next couple of years , driven by solid growth in underlying auto advertising spend and the on-going shift from offline to online advertising, particularly to automotive vertical website.
Chinese automotive sales grew ~13.5% in 3Q13, a rate that management believes should support healthy growth in automotive advertising spend.
We are raising our estimates for BITA modestly (see Exhibit 2, p. 2) to reflect higher revenue assumptions, driven by the continuing rebound in China passenger car sales growth (13.5% y/y in 3Q13). We're also raising our price target from $15 to $20 to reflect higher estimates and market multiples.


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Tributes have been paid to a father who died in a collision on the A12.
Steve Bint, 59, of Colchester, died after his Ford Mondeo left the road and collided with a tree between Kelvedon and Marks Tey on Sunday.
His wife, Sue, made the following tribute on behalf of his family: "Steve was an amazing person and a dearly loved husband, father, grandfather, brother and friend to everyone who had the pleasure of knowing him.
"Steve believed in 'working to live' and planned to retire this year following 42 years working for the Royal London & FOS.
"He was a huge music and sports fan and loved watching West Ham win and going to quizzes.
"He was the best kind of person anyone could imagine; warm, generous, fun-loving, intelligent and so full of love. Steve will be dearly missed by everyone, particularly his wife and two sons.
"The family request to be left alone and allowed to grieve at this very difficult time."
Police are continuing to appeal for any witnesses to contact the Serious Collision Investigation Unit on 101 or email firstname.lastname@example.com


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SAN FRANCISCO — San Francisco police have arrested a man in connection with a homicide on Sunday morning, police said.
Andre Reid, 28, of San Francisco, who police believe stabbed and killed Eric Avila, 52, of San Francisco on Sunday, was spotted in the 2600 block of Mission Street at about 6:10 p.m. Monday.
He was then arrested on suspicion of the murder, police said.
The stabbing happened near 25th and Connecticut streets in the city's Potrero Hill neighborhood at about 2 a.m., police said.
Avila was taken to San Francisco General Hospital where he was pronounced dead.
The murder remains under investigation, police said.
Anyone with information is asked to call San Francisco police at (415) 553-1145 or anonymously at (415) 575-4444, or text a tip to TIP411 and begin the message with "SFPD."
Copyright © 2013 by Bay City News, Inc. … Republication, re-transmission or reuse without the express written consent of Bay City News, Inc. is prohibited.


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Qneo Voice Synth is another good audio app to have in your iOS music making arsenal. I've been using it quite a bit adding an extra vocal bit here and there on my tracks. The app is pretty slick and the audio is good. Try having this and Samplewiz's audio plugged into your DAW. You will get some different results rather than simply resampling ITB.
"Voice Synth is a specialized synthesizer for creative voice sculpting, for endless fun and serious productions. Speak, sing, hum and beatbox in the mic, tweak the controls and turn your voice live into a human from baby to tenor, a popstar on AutoPitch, a robot from Cylon to iDalek, a church or close harmony choir, animals from birds to dogs and lions, musical instruments from organs, guitars and a groovy bass to percussions and rich 70?s vocoders, ambient, lush string/storm soundscapes. All effects applied simultaneously, polyphonic and live in real-time with low-latency. One app, two interfaces: dedicated interface for iPad, and a compact interface for iPhone and iPod that includes all features" – qneomusic.com
For more info: qneomusic.com