text:
Study of Recombinant Human Insulin-Like Growth Factor I in Patients With Severe Insulin Resistance
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
OBJECTIVES: I. Determine the efficacy and toxic effects of recombinant human insulin-like growth factor I (rhIGF-I) on carbohydrate tolerance, insulin action, insulin secretion, hyperandrogenism, and hyperlipidemia in patients with severe insulin resistance who have failed other therapies.
II. Determine the dose and time response of rhIGF-I on carbohydrate homeostasis and secondary abnormalities in this patient population.
III. Determine the effect of rhIGF-I on insulin clearance, the regulation of insulin-like growth factor binding protein 1, the regulation of sex hormone binding globulin, and hypothalamic pituitary gonadal axis in this patient population.
|Insulin Resistance Hyperglycemia
|Drug: insulin-like growth factor I
|Study Type:
|Study Design:
|Masking: None (Open Label)
Primary Purpose: Treatment
|Estimated Enrollment:
|Study Start Date:
|April 1998
|Estimated Study Completion Date:
|September 2000
PROTOCOL OUTLINE: This is an open label study. Patients receive the first dose of subcutaneous recombinant human insulin-like growth factor I (rhIGF-I) on day 7.
Patients receive rhIGF-I twice daily 15-30 minutes before breakfast and dinner, and are hospitalized for the first week of therapy. Patients return for an outpatient exam on day 19 of rhIGF-I therapy. Approximately 30 days into the therapy, patients are readmitted to the clinical center for repeat screening tests. Patients then receive maintenance therapy of rhIGF-I for up to 6-12 months. A washout period follows the maintenance therapy phase.
Patients are followed weekly, biweekly, or monthly depending on blood glucose response of patients off rhIGF-I therapy. Weekly phone contact with study coordinator is mandatory during this time.
Completion date provided represents the completion date of the grant per OOPD records
|Ages Eligible for Study:
|14 Years to 65 Years (Child, Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
--Disease Characteristics--
- Hematologically proven severe insulin resistance with or without diabetes
- Fasting insulin greater than 40 U/mL
- Post glucose insulin greater than 300 U/mL (unless overt diabetes mellitus is present)
--Prior/Concurrent Therapy--
Endocrine therapy: No concurrent oral hypoglycemic agents and/or insulin
Other: No concurrent birth control pills
--Patient Characteristics--
- Not pregnant
- Negative pregnancy test
- Effective barrier contraceptive method must be used by fertile patients
- Good health
Please refer to this study by its ClinicalTrials.gov identifier: NCT00004419
|United States, Massachusetts
|Beth Israel Deaconess Medical Center
|Boston, Massachusetts, United States, 02215
|Study Chair:
|Alan C. Moses
|Beth Israel Deaconess Medical Center
|ClinicalTrials.gov Identifier:
|NCT00004419 History of Changes
|Other Study ID Numbers:
|Study First Received:
|October 18, 1999
|Last Updated:
|March 24, 2015
Keywords provided by FDA Office of Orphan Products Development:
endocrine disorders
insulin resistance
rare disease
Additional relevant MeSH terms:
Insulin Resistance
Glucose Metabolism Disorders
Metabolic Diseases
Insulin, Globin Zinc
Complement Factor I
Hypoglycemic Agents
Physiological Effects of Drugs
Mitosis Modulators
Molecular Mechanisms of Pharmacological Action
Complement Inactivating Agents
Immunosuppressive Agents
Immunologic Factors
ClinicalTrials.gov processed this record on September 20, 2017


text:
Otto Porter looked pretty good tonight. He's a bit of a matchup problem for us. I think we are going to need Watford to step up and play solid D on him.This quote is hidden because you are ignoring this member. Show Quote
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Otto Porter looked pretty good tonight. He's a bit of a matchup problem for us. I think we are going to need Watford to step up and play solid D on him.
I hate to be a downer but Georgetown is a bit more skilled offensively than Georgia.
Georgetown is way, way better than Georgia, no doubt. I was pleased with the activity on the defensive end by the Hoosiers tonight. It's not going to be an easy contest, but one I think IU can prevail in over the course of the game.
Take me out to the black, tell 'em I ain't coming back. Burn the land and boil the sea, you can't take the sky from me.
I was terrified Shabazz would go off in his second game so I'm actually OK with G'Town. I recognize they are a good team
With G'Town's size tonight do you tweak the starters if you're Crean? Go to the group that started the NCAA tourney games maybe? Hulls, Oladipo, Sheehey, Watford, Zeller.
Also, once we can get Hollowell to settle down and cut down the TOs he is going to be a big net positive for us. 3 and 5 in 13 minutes last night, but the 3 TOs really held us back during his time on the court. If he can cut that down he is going to be such a great X factor going forward.
Does Yogi always kick his feet on his jumpshot? I've seen it a couple times now. He really needs to get out of that habit.
It was funny hearing Bob Knight say "Indiana".
EDIT: Whoops, looks like it's just my ignorance.
Learn something new every day.
Somebody on Peegs said they had a source that said Perea and Jurkin have been cleared and will suit up tonight. Not confirmed yet, but the thread has stayed up for a half hour.
I hear the ruling is at 6pm. Stupid secretive NCAA
They gotta get the innocent peons out of the building to save em from the angry horde...
"Nobody wants to play against Tyler Hansbrough NO BODY!" ~ Frank Vogel
"And David put his hand in the bag and took out a stone and slung it. And it struck the Philistine on the head and he fell to the ground. Amen. "
Looks like the decision won't come in time. It is an absolute travesty that Shabazz is eligible right now and Hanner and Peter are not.
Georgia handing it to UCLA so far. That close game isn't looking so bad now. Maybe Georgia just plays to the level of its opponents.
We should still win, even without them.
To be honest, not real impressed with Painter, especially given the pricetag.
So far this game with Georgetown has been extremely competitive. The size the Hoyas bring is quite impressive.
Take me out to the black, tell 'em I ain't coming back. Burn the land and boil the sea, you can't take the sky from me.
hollowell needs to not be so sloppy. that was an unnecessary pass.
We would be up 10 if not for Hollowell. Plus size is that leaves the other guys fresher for the second half at least, when their guys aren't as fresh.
so guess jurkin and hanner did not get cleared?
This is feeling like a loss.
I wonder if Sheehey picked up Zeller's illness. He looks way off recently.
In other non-new news, Hollowell is a walking turnover.
Take me out to the black, tell 'em I ain't coming back. Burn the land and boil the sea, you can't take the sky from me.
Gtown is shooting really well from perimeter, but IU has had no answer for their combo of length and athleticism.
I'd rather die standing up than live on my knees.
-Emiliano Zapata

subset: commoncrawl


text:
Come on England!
This week's Keighley News contains a superb glossy A3 World Cup wall planner, with an England poster on the opposite side.
Fill in all the match scores up to, and including, the final from this summer's tournament in Brazil.
Be sure to buy your copy of the Keighley News before stocks run out. Great value for just 80p.


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Don't miss stories, columns and photos, available only in the Aug. 21 print and e-editions of The Mendocino Beacon. Content you won't find online includes:
• MUSD will not sell MCN
• Photos from 40th annual Great Day in Elk
• Plastic bag ban takes effect county-wide
• Caspar reunion picnic
• Mendocino Coast Clinics' Dr. Lawrence Goldyn meets with President Obama
• Coast Science Insights with Dr. Walt McKeown
• Greenwood/Elk news from Charlie Acker
• Special page: Senior Living
• Special page: Health and Wellness
• Special section: 24-page Paul Bunyan Days guide to events
There are more stories, plus the tide table, school and Senior Center menus, letters to the editor, crossword puzzle, sudoku, legal notices and ads from local businesses.
Start a subscription and have our award-winning weekly community newspaper conveniently delivered by mail. Or, read the newspaper wherever you go - on your computer, tablet or smartphone by subscribing to our e-edition.
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The family of Suzanne Newton, the Melksham woman found dead on Sunday today paid tribute to her.
A statement from her family read: "Sue was a much loved mother and daughter. A loyal friend to all who knew her.
"She was hardworking and her joy came from her son, of whom she was so proud, her little dog and her horses. She will be missed by so many people."
The family has called for privacy, and do not wish to be identified.
Mrs Newton, 45, was found dead at her home in Barnes Wallis Close, Bowerhill on Sunday morning. Her husband Richard Newton, 51, has been charged with her murder, and will appear before Bristol Crown Court on Monday.


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Jan. 10, 2005
Co-Op Grants Fund Programs to Make Science Fun
AUSTIN, Texas — According to the 2003 statewide Texas Assessment of Knowledge and Skills (TAKS) summary reports, more Texas students are underperforming when it comes to science in schools. The latest round of 15 grants totaling $394,266 from the Texas Parks and Wildlife Department may help address that issue and promote outdoor recreation and wildlife conservation.
Grants officials say they have noted a trend in the latest round of applications from groups seeking funding from TPWD's Community Outdoor Outreach Program (CO-OP). And that is that many grant applicants plan to invest in students' science knowledge as a way to preserve our state's natural resources and environment.
"We have groups that come up with amazing programs to help target this population of students because they have concerns about what will happen to the state's natural resources," said CO-OP Program Director Darlene Lewis. "They are partnering with schools and after-school programs to help make science fun, while also addressing other community concerns, such as latch-key students, crime prevention programs as well as getting kids outdoors for a little exercise as well. It's a win-win for Texas."
The CO-OP program has funded 350 outdoor education programs since 1996 and has a current annual budget of $800,000. Applicants can request as much as $30,000 to help cover the cost of equipment, supplies, transportation and facility use fees.
To learn more about CO-OP grants, call Lewis at (512) 912-7124. The next grant application deadline is March 1.
The following organizations are receiving CO-OP grants:
- Austin—American Youth Works —Project SOL (Service/Outdoors/Leadership) will conduct a series of camping, backpacking, and canoeing trips for participants in the AYW/YouthBuild/AmeriCorps program, combining service, education and recreation in Texas State Parks. $20,496.
- Austin—Friends of the Colorado River Foundation – 250 female at-risk folks will be overnight camping, rafting and fishing while learning problem-solving, decision-making and confidence-building using the outdoors. $22,084.
- Austin—Camp Fire USA Balcones Council – This project will consist of a series of Outdoor Skills trainings for children and their parents. Families will participate in Explore Texas, Texas Junior Naturalists and other TPWD programs at several state parks. $14,453.
- Corpus Christi—Youth Odyssey – At-risk youth will participate in 12 wilderness adventure trips that include rock-climbing, canoeing, kayaking and more, to help promote the development of core life skills and outdoor skills. $30,000.
- Dallas—Freshwater Angler Association, Inc. – Children participating in this program will learn basic fishing skills, fish identification, habitat and ethics. $26,535.
- Del Valle—Popham Elementary School – Project Science is a series of activities correlated with the science-learning objectives for kids from preschool through sixth grade. The events will take place on the school campus, Texas state parks and other community locations. $30,000.
- Devine—City Kids Adventure – 450 inner-city kids from San Antonio will be exposed to camping in state parks, fishing, hunting, plant/wildlife identification, and canoeing. $30,000.
- Edinburg–University of Texas-Pan American - Both high school and university students will get hands-on exposure to diverse plants and wildlife and wildscaping activities. $30,000.
- Fort Davis—Chihuahuan Desert Research Institute – Funding will allow kids from Brewster, Jeff Davis, Pecos and Presidio counties to participate in outdoor education programs. $24,810.
- Houston—Frank M. Black Middle School PTA – Students will participate in "Wilderness Education," focusing on science, math, language arts, social studies, art and physical education. Huntsville State Park staff will participate in the program as instructors. $29,960.
- Houston—Macedonia Outreach Center – After-school participants will assist biologists in conservation research projects, aquatic education programs, birding activities and camping. $30,000.
- Hurst—Education in Action – 500 outstanding students in Texas will get to participate in a 10-week long Lone Star Leadership Academy program which includes camping and rafting. $30,000.
- Rotan—Fisher County Healthcare Development Corp. – Program activities such as birding, camping, fishing, hunting and mountain biking will be offered to at-risk students. $29,256.
- San Antonio—Forever Foundation for Texas Wildlife – 250 disadvantaged kids will experience hunting for the first time. $30,000.
- Sherman—Austin College – Summer field trips will benefit children from the Boys & Girls Club and Girls, Inc. of Sherman. Activities will include visits to state parks, and opportunities for birding, wildlife viewing and nature hiking. $16,672.
On the Net:
- CO-OP grants: http://tpwd.texas.gov/grants/coop/
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(5.4.16 i)


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CONCORD, N.C. — The main characters that make up Earnhardt Ganassi Racing are primarily the same cast as a year ago.
So for 2013, there is hope around the organization of same players, better story.
MORE: Clint Bowyer a redneck | Calmer Kurt Busch | Harvick-Childress relationship
Most teams wouldn't have done it this way, keeping both drivers and crew chiefs together after Jamie McMurray and crew chief Kevin Manion finished 21st in the Sprint Cup standings and Juan Pablo Montoya and crew chief Chris Heroy finished 22nd.
"We're not afraid to make changes, but we're not going to make change for the sake of making change," team owner Chip Ganassi said Wednesday during the Sprint Media Tour.
While the team has struggled the past two years, it still is nearly fully sponsored. The team announced a 10-race deal with Cessna for McMurray, who also has seen his McDonald's sponsorship increase from 13 to 15 and Bass Pro Shops stick around for two races despite moving the bulk of its money at Stewart-Haas Racing.
Now the team hopes it can be more successful on the track. After wholesale changes in its competition management prior to 2012, following a season that Ganassi called "pathetic," EGR hasn't seen a huge jump in results.
"It didn't translate as fast as I would have liked it to on the track, but … we're light years ahead of where we were a year ago," Ganassi said.
McMurray said the team panicked a little when it got behind in the move to increased rear skew in the cars during 2012.
"A lot of stuff we were trying wasn't making it better and some things were making it worse," McMurray said. "You were trying to figure out where you're speed is. … Obviously we didn't finish where we wanted to, but I feel like we learned a lot towards the end of last year, and I think that's why you didn't see any changes."
Montoya said both teams struggled and both drivers got into more accidents that hurt potentially decent results.
"If you keep changing stuff, it's going to make things worse," Montoya said. "We know what we need to do. Everybody knows. From our side, we just had a lot of bad luck. Our performance wasn't there either, but we had 10 (races we didn't finish among us). … It's what happens.
"If one side of the company or the team, like the 1 car (of McMurray), was winning races and you were running 25th every week, then you'd have to make a big change."
Ganassi would not confirm that both drivers' contracts are up after this season.
"I don't know (if that) information is correct," Ganassi said about the drivers' contracts being up. "It's like any other business. It's performance-based. We're based on results. … We haven't gone to a race yet in 2013, so it's a little early to be talking about 2014."
If Ganassi does make a change, it won't be because he didn't give his drivers a chance. He has switched from Earnhardt Childress engines to Hendrick Motorsports engines this year.
"Last year, I would have pulled my hair and I probably would have made some changes," said team co-owner Felix Sabates. "But Chip didn't. … He never lost confidence in the drives and neither did I, and for sure we didn't lose confidence in our crew chiefs."


text:
New NECA Instruction Video...
NECA has released a new video showing off their latest 7-inch Robocop action figure, now with a spring-loaded holster. The video not only shows off this fan-requested action gimmick, but provides collectors with a closer look at the figure itself.
The Spring-Loaded Holster ROBOCOP Action Figure is shipping now and should be at retail late September/ early October priced at around $16.99. You can pre-order yours today at many fine retailers, such as BigBadToyStore.com and ToyWiz.com.
To insure your action figure collection, get in touch with Collectibles Insurance, the official insurance company of the Figures.com network. Say "Figures.com" to get 5% off your first term premiums.
To buy action figures, take a look at BigBadToyStore.com, Toynk.com, PastGenerationToys.com, BriansToys.com, ToyWiz.com, and MonkeyDepot.com.
For action figures, statues and sculptures, go to CSMooreStudio.com.


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EVE and some of its most popular ships now available with no monthly subscription. Great for new and returning EVE players.
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EVE Online is peerless. Its importance stands in isolation because no other developer has even attempted to match what it does, let alone tried to surpass it. - PC Gamer More information For all that it's just pixels on a screen and data on a server, EVE is real, and what you do matters, in a way that handing in quests or running dungeons in other games can never approach. - Medium More information
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Over 75,000 applications
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text: For Maryland, move to Big 10 all about the money By Norman Chad November 25, 2012 Story Share OK, LET'S QUICKLY run down the upside of the University of Maryland's sudden move to the Big Ten:Road trip to Columbus!Midwest farmers' daughters really make you feel all right.Cold hard cash.Yes, it's all about the money. So let me congratulate my misguided alma mater for being the latest winning contestant on "The Price Is Right.""The University of Maryland, come on down!!!"Man, they ran to the bank in a hurry with that first Big Ten check.Sure, I understand that's it's a loot-first-ask-questions-later culture. But Maryland was in such a rush out the door, it didn't even bother to leave the Atlantic Coast Conference a Dear John letter.This is how it went down:A feckless Wallace D. Loh, university president, took an offer he couldn't refuse to the feckless university board of regents, which, after hearing Big Ten backing from feckless former men's basketball coach Gary Williams and the feckless student government body, then deliberated for, oh, 10 or 15 minutes before voting in favor of the proposal. (Williams - who graduated 8 percent of his players from 1999 to 2003 because, well, that wasn't his charge as an educator on campus - is a $400,000-a-year university athletic-department employee; the chances he would publicly endorse this move, brought to him by the president and the athletic director, were 100 - no, maybe 105 - percent. And the student government there has about as much do with governing as college basketball has to do with college.)This was a momentous decision, made in secret - almost certainly breaking state law, in violation of the Maryland Open Meetings Act - without any public discussion. Spiritually, it was a reprise of the Mayflower moving vans leaving Baltimore for Indianapolis in the dead of night in March 1984, only this time Loh was driving the big rigs.Now, nobody is questioning the financial wisdom of Maryland's move - though it comes with a $50 million exit fee it now owes the ACC - and everybody is applauding the likely restoration of several non-revenue sports cut from the budget a year ago.But sitting in my off-campus ivory tower, I must ask the same question I've asked before:Is it possible for a great university not to have Division I athletics? Actually, I would argue it's preferable for a great university not to have Division I athletics. Simply put, it makes sense to say no to intercollegiate athletics and yes to intramurals. If we're trying to follow the Greeks' sound-mind-and-body ideal, why should it just apply to a handful of elite bodies?Remarkably, Spelman College in Atlanta just made this very decision, announcing its withdrawal from Division III intercollegiate athletics. "Hoping to replace organized sports for the few with fitness for all," as the New York Times put it, Spelman determined it made little sense to spend $1 million annually on 80 student-athletes when it could redirect time and money to the physical welfare of the entire 2,100-student body.I realize my College Park brethren - who refuse to rise and revolt against the athletic industrial complex that rules the day - will reject this option. So I have a more pragmatic proposal that keeps Maryland in the ACC and solves the fiscal crisis:Open a casino on campus!(You don't even have to recruit "student-gamblers" - they're already there.)Maryland voters just approved Las Vegas-style table-games gambling. Replace vending machines with slot machines and library tables with blackjack tables, and we're talking a new weight room for the football team within 18 months!!! At a minimum, I'd open a card room in the Student Union. Heck, the gent who just won the World Series of Poker Main Event, Greg Merson, briefly went to Maryland. So let's break ground on the Greg Merson Poker Room - of course, first I'd make him come back to College Park and complete his degree.Ask The SlouchQ. Jack Taylor or Jimmy Chitwood? (Josh Prewitt; Milwaukee)A. I don't want to take anything away from a fella who scores 138 points in a game, but afterward he said, "It felt like anything I tossed up was going in." Really? He missed FIFTY-SIX shots.Q. I know it's Division III, but do you rank Jack Taylor's 138-point night on par with Kobe Bryant's 81 against the Toronto Raptors in 2006? (Jim Anderson; Fishers, Ind.)A. Again, I don't mean to denigrate Taylor's feat, but from a defensive standpoint, once a guy reaches, say, the 85-point mark, don't you start to double-team him?Q. You're an L.A. guy and a D.C. guy - how come Gloria Allred always shows up at the scene of a crime? (Patrick O'Leary; Penn Hills, Pa.)A. She's a bright lights/big city ambulance-and-Lincoln-Town-Car chaser. And if she ever represents the Washington Wizards, then you'll know they've hit rock bottom.You, too, can enter the $1.25 Ask The Slouch Cash Giveaway. Just e-mail firstname.lastname@example.com and, if your question is used, you win $1.25 in cash! Story Share Story Share Trending Now 1 Deer in 8 WV counties found dead from EHD 2 'Heroin(e)' spotlights women helping combat Huntington's drug crisis 3 New company planning $73M synthetic fuel plant in Greenbrier County 4 YWCA Charleston's Women of Achievement to be honored in March 5 Area EMS workers return from assisting with Irma recovery Slow start has Mountaineers searching for answers Previous Story Class AAA all-state volleyball team list Next Story


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May 2015
To understand osteoporosis, it is important to learn about bone. Made mostly of collagen, bone is living, growing tissue. Collagen is a protein that provides a soft framework, and calcium phosphate is a mineral that adds strength and hardens the framework. This combination of collagen and calcium makes bone strong and flexible enough to withstand stress. More than 99 percent of the body's calcium is contained in the bones and teeth. The remaining 1 percent is found in the blood.
Two types of bone found in the body—cortical and trabecular. Cortical bone is dense and compact. It forms the outer layer of the bone. Trabecular bone makes up the inner layer of the bone and has a spongy, honeycomb-like structure.
Throughout life, bone is constantly renewed through a two-part process called remodeling. This process consists of resorption and formation. During resorption, special cells called osteoclasts break down and remove old bone tissue. During bone formation, new bone tissue is laid down to replace the old. Several hormones including calcitonin, parathyroid hormone, vitamin D, estrogen (in women), and testosterone (in men), among others, regulate osteoclast and osteoblast function.
Think of bone as a bank account where you "deposit" and "withdraw" bone tissue. During childhood and the teenage years, new bone is added to the skeleton faster than old bone is removed. As a result, bones become larger, heavier, and denser. For most people, bone formation continues at a faster pace than removal until bone mass peaks during the third decade of life.
After age 20, bone "withdrawals" can begin to exceed "deposits." For many people, this bone loss can be prevented by continuing to get calcium, vitamin D, and exercise and by avoiding tobacco and excessive alcohol use. Osteoporosis develops when bone removal occurs too quickly, replacement occurs too slowly, or both. You are more likely to develop osteoporosis if you did not reach your maximum peak bone mass during your bone-building years.
Women are more likely than men to develop osteoporosis. This is because women generally have smaller, thinner bones than men have and because women can lose bone tissue rapidly in the first 4 to 8 years after menopause because of the sharp decline in production of the hormone estrogen. Produced by the ovaries, estrogen has been shown to have a protective effect on bone. Women usually go through menopause between age 45 and 55. After menopause, bone loss in women greatly exceeds that in men. However, by age 65, women and men tend to lose bone tissue at the same rate. Although men do not undergo the equivalent of menopause, production of the male hormone testosterone may decrease, and this can lead to increased bone loss and a greater risk of developing osteoporosis.
Osteoporosis is preventable for many people. Prevention is important because although there are treatments for osteoporosis, a cure has not yet been found. A comprehensive program that can help prevent osteoporosis includes:
The National Institutes of Health Osteoporosis and Related Bone Diseases ~
National Resource Center acknowledges the assistance of the
National Osteoporosis Foundation in the preparation of this publication.
This publication contains information about medications used to treat the health condition discussed here. When this publication was developed, we included the most up-to-date (accurate) information available. Occasionally, new information on medication is released.
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NIH Pub. No. 15-7876
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If you need more information about available resources in your language or another language, contact the NIH Osteoporosis and Related Bone Diseases ~ National Resource Center at firstname.lastname@example.com.
The NIH Osteoporosis and Related Bone Diseases ~ National Resource Center provides patients, health professionals, and the public with an important link to resources and information on metabolic bone diseases. The mission of NIH ORBD~NRC is to expand awareness and enhance knowledge and understanding of the prevention, early detection, and treatment of these diseases as well as strategies for coping with them.
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5 Weird Planetary Systems
Soon, if all goes according to plan, Space Exploration Technologies, or SpaceX, will become the first private company to dock with the International Space Station. The mission was originally scheduled to launch on February 7, and though the company just announced a delay to work out some final launch details, its mission should be the first real test to show that spacecraft built, owned, and operated by private American companies can accomplish what space shuttles did in orbit for so many years.
After launching from Cape Canaveral aboard a SpaceX Falcon 9 rocket, the unmanned, solar-powered Dragon, carrying provisions for the station's six astronauts, will perform a flyby of the space station to test precision maneuvering abilities. If these tests go without a hitch, the capsule will draw near enough to be captured by the station's robotic arm. After its mission, the Dragon will splash down off the California coast for recovery. SpaceX stands to gain $1.6 billion for a total of 12 cargo flights to the station, in addition to the upcoming test flight. SpaceX is already working with NASA seed money to prepare the Dragon for manned flights by the end of 2014.
Company founder and CEO Elon Musk is already looking far beyond the ISS flight. SpaceX is also working to make its rockets and its spacecraft reusable; he says that's the key to making space flight affordable enough to allow, say, human colonization of Mars. Musk's plans include incorporating landing gear into future Falcon 9s and Dragon capsules. Each of the two rocket stages would fly a controlled trajectory back to Earth after accomplishing its mission of pushing a Dragon capsule into orbit, and touch down gently on land for refurbishment. Rather than parachuting to a water landing, the Dragon capsule would fire its own onboard rocket motors to make a precision landing on land as well.
When PM paid a visit to SpaceX headquarters in Hawthorne, Calif., last week, the normally cool-under-fire CEO admitted he and his company have their hands full at the moment. "We are just extremely stressed right now preparing for the docking next month," he said, "plus developing the new version of Falcon 9 with upgraded performance and reusability." SpaceX engineers are also working to modify the basic Falcon 9 design for high-altitude launch from what is to be the world's largest airplane—part of the Stratolaunch project announced by Microsoft billionaire Paul Allen last month.
Here's a look at what we saw during our stop at Musk's home base.
A model of Iron Man lords it over the SpaceX factory floor. The factory served as the location of the evildoer's lair in the film Iron Man 2 in which Musk had a cameo. Note Iron Man 2 star Scarlett Johansson's autograph on the breastplate.
The Future of Space Exploration on Display in NYC


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Older Women Dating Younger Men and Older Men Dating Younger Women Review
There is a growing trend of older women worldwide who are attracted to younger men and go after them. Just as with any phenomenon, a trendy behavior is frequently assigned trendy terminology or slang words. It just so happens that the categorized term for women who prefer younger men happens to be a cougar. Quite simply put the term for a woman who prefers to gravitate to a younger man and date them on a consistent basis is a cougar. This concept can be contributed to a woman by the name of Valerie Gibson.
#1 Date A Cougar
DateACougar is A Little Cougar Background – In 2001 Valerie wrote a book which was published, that has a very erotic concept to it. It centered around older women who could be cast into the role of stalking felines, in this case, cougars who would go after the rabbit prey, who happened to be young men. Her publication basically was an informative guide for older mature women who loved the thrill of dating younger men. Ever since this book hit the press the term cougar has been cast for women who actively seek out younger men to date.
Now this whole concept is a little more elaborate, intricate, and intriguing than it appears on the surface. Throughout this communication, I will go into detail about various angles and variations stemming from this intense attraction and more. Basically, I will elaborate on what I call the older younger syndrome! This syndrome involves both older men attracted to younger women, as well as older women attracted to younger men.
#2 Mlif Dating
Passion.com – The Older Younger Syndrome! The various divisions that I will shed some light on include older women dating younger men, older women dating a younger man, older men dating younger women, the age differences in relationships, older women younger men, older women younger men relationships, older women looking for younger men, older man-younger woman relationship, dating a cougar, and cougar chat. This will be some very entertaining and illuminating information. In order for you to do your own personal follow-up, I will list some pertinent websites that will enable you to follow up and explore the various areas listed directly above, in this paragraph.
These particular sites will provide detailed information and are named one through four; You will find that the information available on these particular sites will complement your curiosity, your need to know facts and flat out inquisitiveness.
#3 Cougar Fling
Evolution of Older Women Dating Younger Men,This type of relationship can start many different ways and take off in a number of different directions. Older women dating younger men is not quite that uncommon. To the extent more seasoned ladies dating more youthful men, a youthful buck who hasn't been in the working scene throughout the entire relationship may be less fiscally stable than an established woman, so you're consequently the woman might feel like a sugar mother. You might be OK with the age distinction amongst you and your man, yet your companions are another story. Other ladies might be desirous that a more youthful man is occupied with you, or your companions may be judgmental and doubtful about your new relationship.
Speaking from the older woman's point of view, his companions may believe you're a flop. Raise your hand on the off chance that you have zero enthusiasm for going to clubs. That way of life was for our 20s. Presently we want to rest, we adore being dynamic and proficient amid the weekend and us loath imparting a studio condo to 4 of our closest and dearest companions. In any case, since you have moved past that 20-something life doesn't mean he has. Furthermore, on the off chance that you keep him down his companions may observe you be a stick in the mud.
More than likely he's not searching for something genuine. What's more, here's a definitive danger of dating a more youthful companion: he's simply not as prepared for something genuine as you may be. You are more established, you have encountered increasingly and tested progressively and now you are prepared to settle down with somebody you think about. On the other side, he has more of his needs to experience, he's young and he's not prepared to submit.
#4 CougarMilfs
Get It on is Special Attraction of Older Women Dating a Younger Man,In this kind of relationship, being an older woman dating a younger man, the woman is regularly in control. Some trust that a woman who dates a more energetic man does thusly in light of the fact that she can without quite a bit of a stretch control him; that the man being alluded to will be so awestruck by her thought that he will oblige whatever she says. In any case, that is a speculation that does not as is normally done apply to every condition.
Every now and again, more settled women are as of late isolated, and planning to sow their wild oats. Getting included with a man who isn't hunting down a veritable relationship and needs a huge amount of fun is the perfect game plan.
More young men have the stamina and carefree perspective to satisfy their prerequisite for a wild ride. Along these lines, in the event that you're planning to take in a thing or two between the sheets, look not any more remote than a more settled woman. In light of current circumstances, she's no all the more sexually controlled, acknowledges what she needs, and apparently has a couple traps up her sleeve.
When in doubt, a more settled woman has defied her insecurities and fears head on and has overseen them to the best of her abilities. She likely has enough foundation to perceive what has any kind of effect and what doesn't. In this way, she's over the immaterial claptrap that makes you turned off about women your own specific age. A more settled woman has understood what makes her look fat, and what looks awesome on her, and knows enough about male-female associations with not inconvenience you with polite subtle elements that as a general rule serve to turn men off.
#5 Cougars Net
Traditional Older Men Dating Younger Women,Is there really a standard model of older men dating younger women, or is each individual case unique. Well, this is a simple clarification. Men, who feel they've been "secured" for a really long time or what he considers a marriage of commitment, feel as though he's been tricked of his childhood and his "fun years." It's as though he looks for a more youthful lady to supplant his more established model (spouse) and persuade himself some way or another that dating a more youthful lady will bring back his energy and give him another opportunity to have a fabulous time once more.
A refined man who is dating a more youthful lady is like a time machine. This is about the same time he spends his cash all the more uninhibitedly on indulgent man toys, replaces his closet, puts resources into hair club for men and possibly enlists a fitness coach. A few men date more youthful lady to demonstrate to themselves they haven't lost his touch.
Numerous men more than 40 who confess to needing more children , paying little heed to the way that they might've effectively raised a couple. They trust that dating a more youthful lady, for this situation, is a necessity (or reason) to diminish the chances of any birth imperfections or wellbeing dangers. On the off chance that a more established man hasn't had the opportunity to father a kid, he looks for a more youthful lady for this particular reason. This appears to be more similar to a cultivating arrangement for a few, yet a few men need to bear on their legacy with offspring of their own. Men have organic clocks, as well, on the off-chance that you didn't definitely know. They expect more established ladies can't securely have kids.
A few men have this crazy conviction ladies their own particular age are all the same. I'll share a case. On the off chance that he's had an awful involvement with his accomplice experiencing menopause, honestly it terrifies the poo out of him to consider going through everything over again with another person. Menopause is by all accounts the reason for some fizzled relational unions (or possibly that is the thing that a few men I've conversed with censure it on). In the event that he's ever been internet dating or on a couple sharp daring meet ups with a lady who's still intense about her separation, he all of a sudden supposes they're ALL similar to that.
More youthful ladies, who have never been in a genuine relationship or "polluted" by a terrible marriage, appear like an incredible choice for a more established man looking for an anxiety and show totally free relationship. Shockingly for him, his suspicions about dating a more youthful lady might not be off-base. Most connections require work and participation to make them effective. Thankfully not every single more established man looks for more youthful ladies for a relationship. When you consider what makes an effective long haul, sound relationship last, age is only one thought in various relationship elements to consider.
Why The Age Differences In Relationships
There are many reasons for the age difference in relationships. All things considered, a more youthful lady fulfills a standout amongst the most fundamental human needs association.Youthful grown-up ladies ordinarily have to a greater degree of a requirement for an association. While they will build a career, they additionally need to in the end make a family. Then again, youthful grown-up men are more centered around the requirement for criticalness. They have connections and begin families, yet their essential center is making sense of an approach to make it on the planet. In youthful grown-up connections, these requirements are regularly in a struggle, as the lady needs more closeness and the man is centered around building his profession. More seasoned men and more youthful ladies share that same requirement for an association.
This is one of the barbarous jokes of the dating scene: more youthful men are centered around essentialness and more youthful ladies are centered around the association. Some place around midlife, there is a switch. Sooner or later, a more seasoned man will understand he's wasted his childhood on the quest for force and may have ignored his family all the while. He is burnt out on the rodent race and is looking for more association. At the same time, a more established lady is burnt out on putting herself second after her kids and spouse. She is prepared to retreat to class and seek after the career she put on hold for her family. This is another reason more established men adoration to date more youthful ladies. A young lady is good with him in that she is likewise looking for more association.
Desirable Older Women Younger Men
What are some of the perks for desirable older women younger men hook ups? First and foremost a more youthful man is conveying less psychological weight than a more established man since he hasn't had as much time to experience misfortune, misfortune or injury. This is a gift and a condemnation; less stuff implies a fresh start however it additionally implies he may be unpracticed, which accompanies its own particular issues.
There is no ex-component when dating a more youthful man, he will probably have fewer ex-relationships to fight with on the grounds that he is to some degree new to the dating diversion. An advantage in the event that you despise cumbersome run-ins with exes. You will feel more youthful in light of the fact that his energy and joie de vivre is infectious and will make you feel more youthful. Furthermore, who wouldn't like to feel like a lighthearted 20-something-year-old once more?
You can impact him emphatically. We as all know men can be resolute. (Yes, ladies can be as well yet that is another subject for one more day). Since a more youthful man may not yet be set in his ways, it's more conceivable that he'll get your great propensities and swing to you for guidance.You can awe him with your experience. Furthermore, we're not notwithstanding discussing your involvement in past connections. Think about all the cool things you did when he was still in diapers. When you let him know about seeing Nirvana live, he will be past inspired and desirous.
Chances of Older Women Younger Men Relationships
Following the time when Anne Bancroft and Dustin Hoffman made it cool in the 1967 film The Graduate, older women younger men relationships have taken on a life of its own. Ladies have grasped the cougar part and like it. What's more, it's a well-known fact that Samantha Jones had (numerous) more youthful, hot, male toys. Sex in the City truly could have been called Cougar in the City. A more established lady dating a more youthful man is only a TV dream, it happens in this present reality as well.
It's superb that individuals are additionally tolerating of a wide range of connections. So, it's not generally smooth cruising when a lady dates a more youthful man. Things can be entangled with regards to setting out on a sentimental association with a more youthful person. Here are a few things to consider before you think about dating as a more youthful man.
More youthful men have a tendency to have more vitality. With regards to more established ladies dating more youthful men, consider that they have significantly more vitality—and a wide range of vitality. Better stamina implies they can appreciate more dynamic dates, and no, we're not simply discussing racquetball.
They'll acknowledge your recommendation. A more youthful man will regularly concede to a more established lady's shrewdness. You've obtained a lifetime of experience already and back and you've most likely taken in a thing or two along the way. More youthful men are more open to looking for guidance and astuteness from a more established lady.
Are Older Women Looking For Younger Men
Are more seasoned ladies searching for more youthful men? Totally; This may sound weird yet subliminally they may serve as a mother figure. A more youthful man may infrequently anticipate that you will infant him and he may look to you as a nurturing sort, which is the last thing you need with regards to your sentimental and sexual relationship. You're not appearing to be some man's mother; you're searching for a man. Furthermore, now and then you may get an update that he's still only a kid.
Ironically, he'll anticipate that you will be the grown up. He may stick you with the additionally exhausting and grown up parts of a relationship since you're more seasoned and, well, more adult. Because he is more youthful doesn't mean you have to do his clothing, pay the bills or get after him. Ensure he figures out how to assume responsibility both in your relationship and around the house.
Possibly, quite possibly, you found a more youthful person who doesn't behave, but instead is shrewd past his years. Bravo! You've found the cougar blessed vessel! The main issue is that there's an incredible chance your person's companions are juvenile boneheads. What's more, no one needs to feel like they are keeping an eye on you every time you go out.
How about we be genuine about this particular issue. Older women looking for younger men is a fact. However, in the event that you and your more youthful man experienced childhood in various decades, then there are some encounters and popular society references that you will just not share. He will never recognize what it resembled experience childhood in the 70s and you will never at any point comprehend why anybody prefers Miley Cyrus.
Desired Older Man-Younger Woman Relationship
(From His Point of View)
Here is the more established man-more youthful lady relationship from both perspectives. When you're dating more youthful, you have to remember that development just genuinely blooms with age, and all things considered you could possibly have tons in the same manner as this new young lady. It's an exchange off you should make when dating down.
Along these lines, albeit no psychological weight shadows your association with her, she may not have the experience or intelligence of somebody your age. So also, you would prefer not to scorn her due to this age crevice, recollect on the grounds that you've lived longer doesn't make her any less wise. She's now completely mindful that you're fundamentally more seasoned than her, no reason for reminding her.
A decent proposal then is to locate the best of both universes, somebody who's both more youthful and has that scholarly development that makes the relationship go past the underlying physical fascination. As a more seasoned man, you have the experience and knowledge of the past from your past connections, so utilize that to advantage your more current one.
Given the amazing pervasiveness of separation in present day western culture, and the compelling budgetary danger this involves, ladies more than 30 requests from their connections a high hazard monetary duty , with less attractive returns, when contrasted with more youthful ladies.
(From Her Point of View)
In her eyes, development in a man is very attractive. She needs somebody who is not apprehensive of duty and long haul arranges, which, let's be honest, just truly frames in the wake of playing the field for a few years.When you're youthful and dating, you have to investigate your alternatives until you locate the perfect individual to settle down with.
Ladies lean toward men who've as of now beat this phase of their life. Been there, done that. They don't care for being toyed with or being seen as another indent on a person's bedpost. Men who are searching for duty are constantly favored over the individuals who are simply looking for the sake of entertainment in playing the field.
So at last, dating is still especially about the similarity and association that one feels towards the other. The truth of the matter is, that men are quite often pulled into more youthful ladies yet their stage and circumstance in life, over a significant time span, additionally reflect in their decisions of picking the age of their accomplices. To keep the relationship going solid, you need a harmony between that age hole, whether it's your need to get a vivacity back your routine or the absence of natural weight, each one is distinctive and in that capacity merits special regard for satisfying their necessities.
Dangers of Dating a Cougar
Being a more youthful person who dates a more established lady, the time has come to uncover a danger every one of you youthful folks may take. A hot Cougar is a perilous lady. She appears to be safe at to begin with, yet you should be careful, the risks are genuine. To begin off an attractive cougar expects more. A Cougar is going to expect more from you than any of the young ladies you have dated. She is going to expect regard. She will expect centered consideration. You will be required to bear on a shrewd discussion. The desires in the room are altogether different.
The more established lady – more youthful man relationship can be addictive. You will be stunned after your first date with a more seasoned lady. You may not expect anything drastically distinctive, but rather you are going to be stunned. The more established lady brings a couple of things into the date a more youthful young ladies infrequently has, similar to certainty. Your Cougar will be sure about herself and her life.
Her knowledge, and book insight, as well as genuine insight which prompts enthralling discussion, becomes an integral factor. Her sexual ability could conceivably take your brain to another level of delight, which more youthful ladies have not grown yet. Now and again this part of the relationship is startling. She has trust in what she prefers, and is similarly sure she can satisfy you.
With regards to budgetary dependability, this is a charming expansion to the relationship. She hopes to share costs, and on the off chance that she needs a costly night out is normally upbeat to take care of the bill. The things just said just begin to expose what's underneath, yet you will find they prompt a fast dependence on being with a Cougar. For the unsuspecting person, there are dangers of dating a cougar.
Interesting Cougar Chat
There are a few scientists who say that ladies top a great deal later than men. No big surprise so a hefty portion of them swing to more youthful men! However, it's the physical that draws in them as well as the educated person. In case you're occupied with meeting cougar ladies who affection to talk, look no more distant than Cougar Singles Chat.
There is a gigantic group of women who know exactly who and what they like and need from life and make no statements of regret for it. Find the delights of these more established ladies when you join now. We question you'll have the capacity to oppose their charms for long!
If you're ready to take a test drive, simply sign up and build your individual profile. Next, start chats or extended conversations with both women and men to your hearts content. Before you know it, you'll have a wide arrangement of online companions that you'll soon end up swinging to for the majority of life's inquiries, high points, and low points, and that's just the beginning.
There is no other spot out there that will offer you the things that Cougar Singles Chat has and we promise that your bliss will be number one with regards to the wide determination of cougars who anticipate your landing. They are fun and energizing and can truly give you the knowledge to some of the life's definitive inquiries and help you on your excursion to life. On the off chance that this engages you in any capacity, then you simply need to take the following simple and basic stride of joining our stunning group at Cougar Singles Chat. Essentially visit the connection underneath and get ready for one of kind fascinating talks and interesting cougar chat.
Interesting Cougar Chat
In Conclusion: Here are the site interfaces that will furnish you with a point by point data grouping on a specific region that you might be pulled into, notwithstanding different methods for growing these ways of life, and procedures for truly investigating the potential outcomes of attaching with somebody of comparative interest.


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Joe Walsh at The Fox in Riverside : KCAL Review
Last night, Rock 'N Roll Hall of Famer Joe Walsh performed at the Fox Performing Arts Center in Riverside for a great show, at what is quickly becoming an inland concert jewel.
I've seen Joe Walsh live 3 times, over as many decades. Yeah, Joe Walsh has been around awhile – I guess that means I have too... Read Full Review


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Paws saw the need to rescue adoptable cats and dogs at animal control facilities where the holding days can be as little as 3 to 5 days. Paws never adopts a pet until it has been completely vetted and most importantly spayed and neutered. We network with all shelters with lists of available cats and dogs. If we do not have what they are looking for we find someone who does.
Thank You!
Your message has been sent to Paws Animal Rescue, Inc..
You'll receive a copy, too, at to help you keep track of which pets you've inquired about, and which shelters and rescues you've emailed.
NOTE: Some shelters have physical locations you can visit; some of these shelters may only have pets for a limited time, so please do not wait for a reply—just go visit the shelter! Other organizations are rescue groups run by busy volunteers who may take a while to reply. You can find information about the shelter or rescue group caring for this pet, and their adoption procedures, on the pet's details page on Adopt-a-Pet.com.


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The new "Oh, Snap" emoticon is displayed on the screen where you type a new post. Since the picture is so big, it is kind of distracting and makes the screen untidy.
Might it be moved down lower in the file of emoticons, so it will still be available but not so prevalent?


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CHINO HILLS – A LifeStream community blood drive will be held Monday at Archibald's Drive Thru, 15461 Fairfield Ranch Road.
The drive will be from 2:30 to 7:30 p.m.
All prospective donors should be free of infections or illness, weigh at least 110 pounds, and not be at risk for AIDS or hepatitis.
Information: 800-TRY GIVING.


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Popular "You Score as the Bucs Score" Promotion to Return
The Pittsburgh Pirates today announced the return of the "You Score as the Bucs Score" promotion, offering fans the opportunity to save each time the Pirates score during the upcoming three-game series in San Francisco.
The popular fan-value promotion is returning for a second time in 2014 as fans had the opportunity to purchase tickets for as low as $14 on June 9 through June 12 thanks to "You Score as the Bucs Score." The Pirates scored a total of 16 runs in a three-game series in San Diego on June 2-4.
Now for every run the Pirates score during the three-game series in San Francisco on July 28-30, fans will receive one dollar off the purchase price of Lower Outfield Box and Outfield Box seats for each game during the three-game series vs. the Miami Marlins at PNC Park on Tuesday, August 5 through Thursday, August 7. The regular advance purchase price for Lower Outfield Box seats is $35, while Outfield Box seats are $30, so if the Pirates score 15 runs this week in San Francisco, individual tickets will be made available for just $20 per game in the Lower Outfield Box section and $15 in the Outfield Box section throughout the three-game series at PNC Park.
Games eligible for discount:
Tuesday, August 5 vs. Miami Marlins (7:05 p.m.)
Wednesday, August 6 vs. Miami Marlins (7:05 p.m.)
Thursday, August 7 vs. Miami Marlins (7:05 p.m.)
The promotion will take place during the three games in San Francisco from Monday, July 28 through Wednesday, July 30 and ticket prices will be updated following each game at pirates.com/howmanyruns. Discounted tickets will go on sale approximately 30 minutes following the end of the July 30 game at pirates.com/howmanyruns or by calling 1-877-893-2827, and also will be available for purchase at 9 a.m. on Thursday, July 31, at the PNC Park box office. The promotion will run as long as supplies last.
All three games of the Padres series in San Francisco will be televised on ROOT SPORTS and can be heard on SPORTSRADIO 93.7 The Fan in Pittsburgh and the Pirates Radio Network.


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what is this we couid of won that philly game but tinsman gets injuried badluck strikes again.
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what is this we couid of won that philly game but tinsman gets injuried badluck strikes again.
Bad luck struck... and the blow injured Bender!
Nuntius was right for a while. I was wrong for a while. But ultimately I was right and Frank Vogel has been let go.
"A player who makes a team great is more valuable than a great player. Losing yourself in the group, for the good of the group, thats teamwork."
-John Wooden
What would the odds have been in September of all of this bad stuff happening? It would have been more likely that we win the championship 3 years in a row and become a dynasty.


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Referee commits suicide after police find wife killed in home
By Jeff Goodman
CBSSports.com Senior Writer
Aug. 16, 2011Tell Jeff your opinion!
PrintEmail a FriendFacebook17Twitter18RSSShareCollege basketball and former NBA referee Troy Raymond committed suicide in a New Orleans hotel room late last week just hours after police found his wife's body in their Houston-area home.
Police found his wife, Leslie Anderson Raymond, 41, deceased at their home in Spring, Texas, at 2:08 p.m. on Friday.
Constable Tim Holifield of Montgomery County Precinct Three told CBSSports.com that the medical examiner ruled the cause of death a homicide caused by asphyxiation due to manual strangulation.
Troy Raymond worked one season in the NBA before it was revealed he lied in his media guide bio. (Getty Images)
"We're not prepared to tell you who's responsible," Holified said. "But certainly Mr. Raymond is a person of interest -- and his death brings about more questions than answers."
Holified said that during the course of the investigation while at the residence on Friday, investigators were notified that Troy Raymond had been found dead in a hotel in New Orleans due to a single gunshot wound to the head.
Holifield added that investigators with his office are working jointly with the Jefferson Parrish Sheriff's Office, but would not comment on any correlation between the two deaths at this time.
Sources told CBSSports.com that Leslie Anderson Raymond had recently asked for a divorce -- and Raymond had also been informed by one coordinator of officials that he would not be re-hired to work games next season.
Fellow referee Bobby Bissant told CBSSports.com he was informed that Raymond's wife had been killed from one of Raymond's childhood friends on Friday afternoon -- and while the two were talking, the police called and told the friend that Raymond had committed suicide.
"I still can't believe it," said Bissant, who worked three games this past season with Raymond. "I haven't been able to sleep since I heard the news."
Raymond spent a year in the NBA, but was forced out in 2004 after he was caught lying on his résumé for the referee's media guide. He had written that he attended the University of Colorado and played on the school's national champion football team, according to a 2007 story in the Wall Street Journal, and numerous sources also said he falsified that he was a pilot in the Air Force.
Raymond, 46, worked 17 games in the college ranks last season, primarily in the Southland and Sun Belt conferences.
"He was a very good official," Bissant said.
Sun Belt coordinator of men's basketball officials Mike Wood last talked to Raymond in June and said he "seemed in good spirits."
"We definitely would have used him again this year," Wood said. "He would have made our roster."
Both Raymond and his wife attended Southern University in New Orleans. Leslie Anderson Raymond had two children from a previous marriage.


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Michelle Obama opens Special Olympics in Los Angeles
The three-hour ceremony, broadcast on ESPN, included Special Olympians at every level.
The three-hour ceremony, broadcast on ESPN, included Special Olympians at every level.
LAS VEGAS (AP) – Sergey Kovalev had little trouble taking care of business against an outmatched Nadjib Mohammedi. Now he can look forward t…
CHICAGO (AP) – T.J. Dillashaw successfully defended the UFC bantamweight title, stopping Renan Barao by technical knockout in the fourth rou…
The dogs were rescued and are recovering at an Akron facility.
The latest weather forecast for Youngstown, Ohio and surrounding areas.
Supporters gathered at Mill Creek Park Saturday demanding total transparency after the water issues at the park's lakes.
When summer temperatures soar, a vehicle can quickly turn into a death trap for animals.
The Mahoning Valley Scrappers got a solid start from Shao-Ching Chiang but were not able to capitalize, falling to Brooklyn
The White Sox, who came to Cleveland with six losses in seven games, have outscored the Indians 24-4 in the first three games of the series.
Michael Taylor had a home run and three RBIs and Gio Gonzalez won his fourth straight to lead the Washington Nationals to a 9-3 victory.
A New Cumberland man will serve four years in a facility for youthful offenders for sending pictures of his genitals to a 15-year-old girl.
Citing philosophical differences, the school board on Saturday accepted the resignation of Superintendent Kent Polen.
The league, in its 19th season, currently has 12 teams – down from the high of 16 in the early 2000s.
The fire on the pool deck of the Cosmopolitan Las Vegas hotel-casino caused evacuations and the cause of the fire has not been determined.
Panama won the shootout 3-2 after extra time ended with the score 1-1.
The Cleveland Indians unveiled a bronze statue of Doby, before Saturday night's game against the Chicago White Sox.
While cutting people's hair, the suspect allegedly secretly recorded or took sexually graphic pictures of clients.
Francona said Kipnis is available to pinch hit and expects him to play Sunday in the finale of the four-game series.
The latest weather forecast for Youngstown, Ohio and surrounding areas.
A fire at a high-rise hotel swimming pool sent large plumes of black smoke high above the Las Vegas Strip Saturday.
6,500 athletes from 165 countries have poured into the Los Angeles Memorial Coliseum for the 2015 Special Olympics World Games.
Authorities have confirmed that a 4-year-old boy did not survive after walking away from his grandparents' home.
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So you can store a 3d world in a sparse voxel octree, but youve taken up huge amounts of ram in doing so. Jon Olick says you can get it down to a bit and a half per voxel utilizing some compression techniques... any ideas to how this could be possible?
Why not ask Olick himself?
How do I get a message to him? I wonder if he even has the time...
I guess I was implying he's online and you may be able to find a way to reach him. For example, a comment on his blog on a voxel post may get an answer.
Tell him to make time :lol:
According to his paper, his storage is 8 bytes per voxel. He only mentions positional data is 1.15 bits in comparison to triangle storage. According to his storage structure, 1 byte is allocated for the children mask. A byte has 8 bits and a voxel has 6 possible children (sides of the cube), plus itself so 7 bits in total. 8 / 7 = 1.142 positional bits per voxel. He probably just rounded that up to 1.15. His encoding is similar to how PNG files are encoded before they are compressed with deflate. Stochastic data doesn't compress very well, so if you filter the data to minimize entropy, compression algorithms like deflate will do a much better job. In his case, he stores the relative values instead of absolute values (exactly what PNG does).
thanks for that info, so it is similar to png, i cant really do voxels tho, cause i know how to save a png file, but i dont know how to code it myself.
Ive actually moved to displacement mapping (see my other post http://www.devmaster.net/forums/showthread.php?p=82256#post82256) and its going quite well, and with that yes all i do is literally save the png file and displacement map is compressed.
So far I got my voxel model to be about 1.45 bytes positional data and not sure at all how I would compress colours in the state they are in, so I think im much better off with displacement maps, and then I would get pretty nice compression, even without knowing much about compression.
what do you think nut... would displacement map models compress detail better than a voxel model?
It would work fine for simple terrain, but anything with interior would be problematic. It offers the best compression for what it does, but without interior it's not much of a voxel format With my limited knowledge, I would stick with the classical approach of storing and loading spatial trees. You also get the added bonus of storing and loading LOD levels, which will be important for dealing with memory intensive voxel data.
This is a revival on the old post.
So I finally read what you said TheNut and I finally understand!! (sort of)
So you store the voxels as neighbouring bits from each other, and it comes to about 8 bits a voxel... how do you compress further than that?
I sorta gather entropy is when the data turns to complete noise.
Oh I get it! Entropy encoding is just huffman encoding, can I ask another question? could you use entropy encoding for the colours as well as the neighbour bits? and how well would it do... theres no way youd get 8:1 compression like Jon Olick says... or can you?!?
and by filter, do you mean make all the similar colours the same colour, that would be a good image filter to go into huffman code, is that what you mean?
You must use entropy encoding for anything, because colors and normals eats much more space, than child bits (not neighbour). Also, I suggest using some type of arithmetic coding instead of Huffman (Huffman can compress down to integer number of bits, while arithmetic coding compress further to fractions).
As Olick wrote, store colors as difference to parent with some quantization. Process of quantization is essentially lossy filtering.
everyone seems to know more than me!!! ahhhh!!!


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There are a lot of things to keep track of when you prepare and submit these final forms. The court clerk will return your court forms without filing them if you leave out a required form or some information on a form, or it is not clear what you are asking for. Often the clerk will include an instruction sheet telling you what is needed before the forms can be accepted for filing. If you are not sure what needs to be done to solve the problem, talk to a lawyer or the family law facilitator or self-help center.
Sometimes the forms will be returned with a request that you schedule a court hearing. This usually means that you are asking for something that the judge needs more information about.
If the court requests that you schedule a hearing, contact a lawyer, family law facilitator, or self-help center. You may need to give notice of the hearing to your spouse or domestic partner. When you attend your hearing, be sure to bring anything the clerk's letter asks for, as well as your copies of all the forms you have prepared or received for your case.
The court will probably reject your judgment papers if:


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I think the only ones I havn't heard from about the draft change is Mourning, Kerosene & Diamond Dave00.
Mourning & Kerosene are both on vacation and will return late this week.
Diamond Dave00 must have me on ignore because he doesn't respond to any of my PM's. :cry:
I do have a couple more minor details about the draft I'd like to pass along.
1. As I've mentioned before we will start the draft late on October 21st. I don't want to give a time yet cause I'm just not sure what my plans are for that evening.
2. The draft clock will be set for 24 hours. Please make every attempt you can to keep your draft time down as much as possible. If it looks like someone is dragging their feet a little, I'll let them know.
3. At some point in time we may need to shorten the draft clock. First I will send out an e-mail as well as post a notice on here that the clock will be changed. I'll announce the new draft clock time, 24 hours prior to changing it.


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BOISE, Idaho (AP) - Anthony Drmic scored 19 of his 26 points in the second half, leading Boise State to a 73-47 victory over Nevada on Wednesday night.
Ryan Watkins added 14 points and eight rebounds as the Broncos (19-8, 7-6 Mountain West) recorded their third straight victory.
Deonte Burton had 13 points for Nevada, which had more turnovers (17) than field goals (10) while shooting 26 percent from the field. The Wolf Pack (12-15, 3-10) have dropped four straight games and seven of their last eight.
During one second-half stretch of nearly 11 minutes, Drmic scored 17 of Boise State's 22 points as the Broncos' lead reached 22 points. The largest lead was 71-42 on a 3-pointer by Igor Hadziomerovic with 1:53 remaining.
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It seems almost selfish to search for silver linings too soon among the darkest clouds of utter devastation.
How can anyone begin to contemplate optimism with millions still sifting through unthinkable physical and emotional wreckage?
But such is the natural progression from despair to hope that fuels humanity in the aftermath of catastrophe.
Hurricane Sandy— like South Florida's Hurricane Andrew, the Gulf Coast's Hurricane Katrina and other natural disasters before it— will scar communities, businesses, families and lives indefinitely. Much of what was lost can't be replaced.
Cooperative Effort
Yet it could strengthen a fragile society in ways previously unimaginable.
What a sight it was for New Jersey Governor Chris Christie— a few weeks removed from a rousing keynote at the Republican National Convention— to be back on a national stage, this time praising Barack Obama's swift response to Sandy just days before the election.
That underscores the genuine, apolitical cooperation that has built, rebuilt and will be needed again to rebuild this country.
Destruction, however tragic, drives reconstruction. And many economic pundits were suggesting within hours of Sandy's strike that public works projects will become so significant that they could help boost the nation's GDP as thousands of contractors stalled by the housing market collapse dust off their tools.
Economic Lift
Frank Holmes, CEO of U.S. Global Investors, speculated a day after Sandy struck that damages of $20 billion (later estimates approached $50 billion) could trigger a $100 billion economic lift from related spending.
That, at this early stage, must seem like a hollow consolation to retailers slammed shut by Sandy. Some observers estimated such retailers collectively would take a $25 billion hit in sales during the week following the storm. Burt Flickinger III of retail consultancy Strategic Resource Group revised his November/December retail sales growth forecast from 3.2% to 2.1%.
Independent merchants cut off by Sandy face a particularly difficult recovery— if they recover at all. Still, retailing overall, after the near-term blow, figures to be an instrumental contributor to and benefactor from the post-Sandy recovery as victims restock their homes and lives.
Grateful Return
Home improvement and housewares retailers are well equipped to help restore battered communities in some of the nation's most populous regions.
If you need any further convincing about how essential the products provided by this industry can be to people during their most difficult times, consider this: A HomeWorld Business associate said he was grateful to return to a fully functioning office two days after Sandy left him in the dark in part because he could prepare and savor a fresh pot of coffee.
It is hardly selfish to seek relief wherever one can from havoc and uncertainty. The housewares business is in a strong position to help ease the devastation of Sandy and participate in a reconstruction that could help lift the long-term economic prospects of an entire country in the process.
It's never too soon to pursue silver linings.


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Linchpin of future Camden Waterfront redevelopment is haven for drug users
In the spirit of the new "Say Something Nice About Camden" marketing campaign, let us say this: Since the State of New Jersey cut down the dense patch of trees next to the Benjamin Franklin Bridge, heroin addicts are no longer shooting up there. Mission accomplished. But because this is Camden, there is unfortunately a downside to this victory.
Residents say some of them are instead injecting the drug in an abandoned RCA factory on the Delaware River waterfront -- the city's primary destination for tourists, Rutgers students and urban pioneers. They claim a group of five to six addicts travel from Burlington County via the NJ Transit River Line five to six times per day, five to six times per week to buy and use drugs in the vicinity. These users have also been observed during daylight hours snorting heroin on the outdoor train platform that services the district.
The building they favor is RCA Factory Building No. 8, which is slated for conversion to 86 luxury condo units by Philadelphia real estate mogul Carl Dranoff, who redeveloped and owns the upscale Victor apartments next door. The project has frustrated area residents for years, as Dranoff initially promised to have the so-called Radio Lofts, reported to be priced between the low $300,000's and high $400,000's per unit, ready for market by the mid '00s. But the discovery of toxic dioxin in the concrete during the environmental remediation phase coupled with a lack of public funds to remove it has stalled progress, and since work stopped last winter the 88-year-old structure has stood partially boarded up and roofless.
"It's a cancer on the neighborhood," said Jonathan Latko, president of the Cooper-Grant Neighborhood Association that represents the interests of Riverfront residents. "It's the broken window theory. Disrepair leads to minor crimes in the neighborhood, which then lead to bigger crimes. Except Radio Lofts has no windows. So I guess it's the 'no window' theory."
The irony is that Cooper-Grant has relatively little crime. Populated mostly by college-educated professionals and students, it's one of the city's only contemporary residential success stories. But in the ten years that have passed since parties signed an option agreement for the building, an eagerly anticipated Dranoff project to build a $400 million mixed-use development along the water's edge still exists only on paper, and stores and restaurants on the ground level of The Victor have come and gone, chiefly failing because of a lack of foot traffic.
Some neighbors worry that Dranoff might abandon the project – and the city – and leave the historic building vulnerable to demolition or eventual collapse. "The longer the building sits with no windows, the more potential for further deterioration of the shell," Latko said.
The Camden Redevelopment Agency (CRA) owns Building 8, with Dranoff serving as the property manager until the day remediation is completed and he purchases it from the city. Dranoff did not respond to several requests for an interview but Sandra Johnson, executive director of the CRA, says not only will Mayor Dana Redd never allow Building 8 to remain in permanent limbo, the project is one of the CRA's top five priorities.
"No, no, no, that's not going to happen. That is not a part of the mayor's vision," she said. "(But) did I think we would be much further along by now? Yes."
Johnson added, though, that she would have to meet soon with Dranoff, who made news last week when The Inquirer reported that an admitted lack of funds was keeping him from beginning to repay a DRPA loan for environmental remediation at The Victor, to ascertain his continuing level of interest. The CRA has already spent $4.7 million worth of public grants on remediation – a figure that was originally expected to cover the entire cost -- and needs $2.1 million more to finish the 15 percent that remains undone.
"We've received no indication that he's backing off but he's a business man so we'll certainly review possible alternatives for him and our city regarding the redevelopment of the Radio Lofts," Johnson said.
"I've already got 700 names on a waiting list - many Victor renters who want to own - and the market will be different when Radio Lofts opens in two years," Dranoff told the Courier-Post two years ago. Three years before that, he acknowledged that he was frustrated with the slow pace of development and attributed it to a high number of personnel changes in city and state licensing and funding agencies. And his website, along with countless old reports and marketing materials published by city organizations, expresses a deep optimism for the impact Radio Lofts can make. "The historic renovation will serve as a residential anchor for the revitalization of the Camden Waterfront," reads a company case study posted on dranoffproperties.com.
Until that happens, Radio Lofts is serving as little more than a haven for drug abusers, and although Latko says police are aware of the problem and have stepped up patrols in recent days, they have yet to stop the flow. Late last month, the CRA cleaned up most of the discarded needles and drug baggies and patched a torn fence that's designed to keep trespassers from entering the building. However, Latko wishes they would erect another gate to prevent people from trespassing on the property.
"We have working families in the neighborhood and I have a daughter. I don't want people shooting up one block from my house," he said. And as for Building 8, "I would love to see the thing fixed but in the meantime I'm not going to let it deteriorate in front of us," he said.
Support provided by
RCA Factory Building No. 8


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