text:
In that regard a Porsche SOTW is hard to beat, because when you casually drop the fact that you drive a Porsche into general conversation, people will often jump to the conclusion that you own and run a car that cost several tens of thousands of pounds. Which you manifestly don't (well, you might, but it won't be your Shed).
It's an appealing idea (providing you don't break the illusion by actually showing your car to those with whom you are conversing), which makes it all the more odd that the Porsche shield doesn't grace SOTW's pixels on a more regular basis.
Perhaps more importantly, although a Shed-level Porsche's sticker price might have fallen from premium levels, it won't have forgotten its premium roots when it comes to running costs. Put simply, while a Porsche like this might be cheap to buy, it is unlikely to be cheap to run.
Still, this particularly 944 looks like a surprisingly non-sheddy proposition. Its interior looks tidy, those refurbished teledial alloys look lovely and the vendor certainly claims to have done plenty of work on it.
Oh, and we do find it odd/worrying that the seller omits any mention of how rusty the car is, but go in with the view that there is no such thing as a cheap Porsche, merely a cheap purchase price and you're unlikely to be disappointed.
So there we have it, a Porsche as SOTW. hope fully that makes up for the three Rovers we've featured in the past six weeks (sorry about that).
Advert is reproduced below:
160,000 miles £1,000
Porsche 944 2.5. The very last of the 2.5's. This car comes in (without doubt) the best colour.
6 months tax
6 months MOT.
The car has done 160k but till feels tight. This was gonna be an ongoing project for me but my girlfriend can't drive the car so it's gotta go.
Electric sunroof, wing mirrors, central locking, Porsche immobilizer, CD, uprated speakers, electric drivers seat, rear wipe etc.
Refurbished Interior. Seats and interior look like a new car (very expensive). Just had new armrest made (not in photo)
Refurbished teledial wheels - look fantastic (again, not cheap)
2 new tyres (50 miles ago)
Headlights (uprated)
Arm rest
Cam belt
Power steering belt
Alternator belt
Earthing strip
All the electrics have been overhauled and everything works.
The bad news:
There is a knocking noise coming from the back on when you come of the power. I'm told this is to do with the clutch but the clutch is fine.
Just drove over 400 miles to Derbyshire and back with no problems - oil pressure, volts, & temp prefect, a real pleasure to drive. Feels like a new car.
There are a few dents in the front wing
The is a whole in the front wing where is got curbed.
The previous owner lost the history but it doesn't matter on a car this age (it didn't matter to me!)
Not that bad for a 22 year old car.
Believe me this is a good solid car and I love it. It drives lovely and I absolutely love the car but after 18 months she has to go.


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The beautiful country mansion, Konstedlund - or as it was perviously called, Kongslevlund - is located at the edge of Lille Vildmose, south east of Kongerslev town.
Legends tell that there was a pirate's castle here which belonged to Store Mogens (Big Mogens), and that the name is connected to this pirate chief. He lies buried in a barrow south of Kongerslev - Store Monshøj.
The original Kongstedlund house was, however, first buillt in 1592 by Niels Juul, and he was the one who changed the name from Kongslevlund to Kongstedlund. Eight years later, he was killed at a Whitsun market in the town of Aalborg, where he got onto a fight with another nobleman - Albret Skeel from Jungetgård near Salling.
The beautiful sandstone portal which adorns the entranceto of the main building was erected by the subsequent owner Iver Krabbe in 1640.
There is no admittance to the public.

subset: commoncrawl


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"Freedom is nothing else but a chance to be better." - Albert Camus
"Appreciation is a wonderful thing. It makes what is excellent in others belong to us as well." - Voltaire
"Everyone's values are defined by what they will tolerate when it is done to others." - William Greider
Rush tweeted a pic of Bynum sitting on the bench with some lol looking hair. Looked like a chick. Wonder why Quis didn't play he played great the other night vs the Celtics.
Last edited by pacer4ever; 11-14-2012 at 10:09 PM.
Again I don't think Vogel is the problem, the problem is the front office.
Watching the Pacers so far this year must be what hell feels like.
I'd rather die standing up than live on my knees.
-Emiliano Zapata
All that goodwill that Larry Bird painstakingly built vanished in a couple of weeks. He must be irate at what Pritchard and Walsh did to this franchise.
PS: No one cares about your fits of rage as well. That doesn't stop you from literring the forum both this season and the previous one, does it? And why would it?
It's a free forum and people are free to express their opinions
Can someone give us an update on the Brandon Rush tweet?! ha
"We've got to be very clear about this. We don't want our players hanging around with murderers," said Larry Bird, Pacers president.
TO on first possession of half and Frank persist with the utterly hollow upbeat clapping.
I'd rather die standing up than live on my knees.
-Emiliano Zapata
Pacers are just mentally gone... never seen anything like this.
"We've got to be very clear about this. We don't want our players hanging around with murderers," said Larry Bird, Pacers president.
Except that it feels like a war zone when things are going awry. If that's how bars are like in the US then fair enough
Gee, the JUST Pacers need 27 pts per qtr in order to make their game average of 88 PPG.
Any bets??
"There's only one way outta this hole.... That's toughness and togetherness..." lol
One, two... whatever it takes...
Nuntius was right for a while. I was wrong for a while. But ultimately I was right and Frank Vogel has been let go.
"A player who makes a team great is more valuable than a great player. Losing yourself in the group, for the good of the group, thats teamwork."
-John Wooden
Walked right into that one.
Positive comment: Paul George put the ball up 11 times in the first half. He did so 16 times yesterday. That's the volume increase I want to see, he just needs to stop making them all long jumpers vs guys he's a half foot taller than.
This is comical.
Ok here is the picture, please don't let children's see it lol
@mg_indy: @espn: Andrew Bynum likes to dress cool and wear his hair in interesting ways -> http://t.co/ljkDcrBN<~This dude...
I keep thinking we've hit bottom, and then the bottom gets lower.
Removed link to my website after a PM from Able.


text:
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text:
|October 25, 2006
Volume 8, Issue 22
|Midwifery Today E-News
"Twin Pregnancy and Birth"
Print Page
Welcome to Midwifery Today E-News !
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Send submissions, inquiries, and responses to newsletter items to: firstname.lastname@example.com.
In This Week's Issue:
Learn about midwifery education!
Are you an aspiring midwife who's looking for the right school? Are you a practicing midwife who would like learn more? Visit our Better Birth Education Opportunities page to discover ways to start or continue your education. You'll find schools for both traditional midwives and CNMs as well as an online continuing education program that will earn you 12 contact hours.
Quote of the Week
"Every [hospital] intervention is a lesson in who really owns your body and your baby's body."
— Jock Doubleday
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The Art of Midwifery
For postpartum compresses, place a large handful of dried yarrow in a quart jar. Pour in boiling water, cover and steep for 2–4 hours or even overnight. You can also use fresh herb. Strain. Dip 4 x 4 gauze pads in the infusion. Fold them in half. Lay out on a cookie sheet in the freezer. When frozen you can package them together with some waxed paper between them to keep them from sticking together. Postpartum moms can place them in the sanitary pad, and also use them on sore nipples or on hemorrhoids.
— Helena Wu
ALL BIRTH PRACTITIONERS: The techniques you've perfected over months and years of practice are valuable lessons for others to learn! Share them with E-News readers by sending them to firstname.lastname@example.com.
Passionate Midwifery Education
Each of us must take responsibility for our own education. This is so even for those who are planning to attend a midwifery school. You need to find the school that will best help you learn your calling in the way you are called. Some of you will be nurse-midwives, others will be direct entry midwives and some will choose to be lay midwives. You need to make sure you can be the best midwife possible within your calling. A key issue is that you will be serving motherbaby and the family and you will need to determine the most important areas of study. This is true even beyond your formal or informal training. Your midwifery, doula or childbirth education will continue for your whole life.
You may find that some of the curriculum is not helpful, but you typically need to do a certain amount of busy work. Your job all along the path of lifelong education is to be the best you can be. Is learning homeopathy more important than pharmacology? The answer will be different for each of you and may change as you journey through your midwifery life. There is no wrong answer but you need to be proactive in your path. I know conference attendees often have difficulty choosing classes—they have so much to learn and be excited about. For most of us, our birth life is one of the most important aspects of our life.
I hope as you look around this amazing world at all the possibilities for your education you chose carefully from the huge smorgasbord of educational opportunities we have today. We can learn from traditional midwives in other countries or from dozens of disciplines. It is an exciting journey. I hope some of you will write and let us know about your path and how you choose what and how to add to your skills.
Our midwifery is often closely wrapped up in our identities partly because we are called to the path that requires all of the love we have to give, then a little more. Welcome to midwifery.
— love, Jan
To read all installments of our column on midwifery education, go to our Better Birth and Babies Blog.
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Twin Pregnancy and Birth
Something about the word "twin" seems to inspire an immediate anxiety attack in all concerned: mother, father, grandmother, midwife, and especially obstetrician. Medical literature abounds with information on multiple gestation and the inherent risks to the mother and her babies. Twins are generally viewed as pathology, and very little is written about the possibilities of achieving an optimum outcome. I do not consider "twinning" to be an anomaly, but a very special occurrence which deserves careful management to ensure safety for both mother and babies. Indeed, there is no reason the mother of twins cannot expect to deliver healthy full-term infants when she is properly educated, has a high level of responsibility, and receives excellent prenatal care.
It is not my intent to either advocate or oppose the idea that the management of multiple pregnancies is beyond the scope of midwifery practice, or that out-of-hospital delivery of multiples should be considered. It is, however, my opinion that if one undertakes the practice of midwifery, one should be knowledgeable about all possible "variations of normal" which may—and are likely to—occur.
If you decide to take on the responsibility of assisting at the birth of twins, you must know there are risks involved. However, there is an element of risk in all birth, so my advice is: Learn all that you can, get as much experience as possible, and proceed as your heart dictates. It is also important to understand that the new parents' needs will be much greater as they embark upon the awesome task of caring for two babies at once. Be prepared to assist them with concerns and to help them find competent support during the early weeks. Recognition of the reality of the "fourth trimester" is vitally important.
— Valerie El Halta, CPM, excerpted from "Twins: A Very Special Occurrence," Midwifery Today Issue 39
Read all of Valerie's article in MIDWIFERY TODAY Issue 39. This article includes "A Study Outline on Twin Pregnancy, Labor and Delivery" for study and application purposes on twin pregnancy, labor and delivery. Order the issue.
News Flash
Lamictal Implicated in Cleft Lip and Palate
The FDA notified healthcare professionals and patients of new preliminary information from the North American Antiepileptic Drug Pregnancy Registry suggesting that babies exposed to Lamictal during the first three months of pregnancy may have a higher chance of being born with a cleft lip or cleft palate. The drug is used to treat seizures and bipolar disorder.
Pregnant women should not take Lamictal without first consulting their physician. More research is needed to verify this link.
For further information see: http://www.fda.gov/medwatch/safety/2006/safety06.htm#Lamictal
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Research to Remember
According to a study of more than 151,000 women in Sweden, those who gain weight, but are not necessarily obese, after their first pregnancy have a higher chance of developing complications during subsequent pregnancies than those who maintain their weight. Complications include pre-eclampsia, gestational diabetes, cesarean delivery, large-for-gestational age birth and stillbirth. The researchers, who used body mass index (BMI) to determine weight increase, suggest that the results of the study lend credence to the possibility to women whose BMI increases prior to pregnancy may also be at risk for perinatal complications.
— Villamor, E. and S. Cnattingius. 2006. Interpregnancy weight change and risk of adverse pregnancy outcomes: a population-based study. The Lancet; 368: 1164–70.
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Holiday Coupon Page 2006
It's not too late to get a jump on Holiday Sales. Advertise your product or service on our Online Holiday Coupon Page. Ads stay up until January 31, 2007, giving shoppers a chance to pick up gifts for themselves after the holidays..
Contact our Advertising Director today at: firstname.lastname@example.com
Forum Talk
Any tips for getting heart tones with a fetoscope at 20 weeks or less—especially on a mom with a little additional weight around the waist? What is the earliest you've managed to hear fetal heart tones with a fetoscope?
— Anon.
Go to our forums to share your thoughts and experience.
Question of the Week
Q: I am a new midwife from Victoria, Australia. The midwifery-led unit I work in is being pushed into providing an obstetric model of care (by the obstetricians) rather than the current woman-centred model of care. This has resulted in the introduction of a protocol requiring that a vaginal assessment be carried out within 1–4 hours of arrival at the unit and 4–6 hourly until babe is born.
This current protocol will remain unchanged unless we can produce some evidence/research supporting nonintrusive methods of assessment. The majority of the midwives, including the unit manager, do not want to see this become policy, and a focus group has been formed to address this issue. Can readers point me in the direction of research that addresses the impact that invasive interventions such as vaginal exams can have on a woman and her childbirthing experience, and any alternate methods of assessment?
— Amy Corlass
SEND YOUR RESPONSE to firstname.lastname@example.com with "Question of the Week" in the subject line. Please indicate the topic of discussion *and the E-News issue number* in the message.
Question of the Week Responses
Q: I have been told that raspberry leaf tea promotes labor. I very much want to have a natural birth, and if this will help me get through it quicker, please tell me how do I drink it, how often, etc. I am 35 weeks already, but I am sure it's not too late to start, or maybe it's too early?
— Donna S.
A: It is never too late nor too early to start drinking red raspberry leaf tea. It is one of the most valuable herbs for the female reproductive system. Unless promoting labour is contraindicated, such as for mutiples perhaps and then only under supervision, definitely drink 3–5 cups a day. Make a pot in the morning, after you have just boiled fresh water; wait for it to stop bubbling and pour it over a couple of tea bags, organic, leave to steep, and enjoy throughout the day. If you need to rewarm it, do so at a low temperature so as not to destroy the vitamins.
— Rachel
A: I have found in my experience as a doula that a cup of red raspberry leaf tea will promote labor and relax mom, though relaxation is the effect of the warm tea more than a medical benefit. I also found that there seemed to be more of an effect with epidural moms than with the natural births. I only give RRLT during active labor or beyond and have noticed that any earlier than that there was less effect unless it is during an early predomal labor, and in that case it does seem to speed things along.
— Ashleigh W.
Responses to any Question of the Week may be sent to E-News at any time. Write to firstname.lastname@example.com. Please indicate the topic of discussion *and the E-News issue number* in the subject line or in the message.
Think about It
All of us have experienced incidents of dystocia with our clients, and in my experience, it is usually psychological. A woman might be an incest survivor, or she might have high control needs, or at the very least she has been influenced by the negative and fearful images of birth in our culture. I have made it my business to watch for and learn methods to ease psychological dystocia. There are so many ways, both prenatally and during birth, we can help our mothers birth easily. In my practice, for example, I do not ask clients to attend childbirth classes; unless there is an instructor who I am certain gives only the most positive and encouraging instruction, I ask that they not attend at all.
The "meta-message" we give our clients in childbirth classes is usually "childbirth is difficult and you cannot do it without much practice and lots of help from professionals." Throughout prenatal care, even with Amish primips who have had almost no information on childbirth, I emphasize that everything is fine, and that having a baby is usually just like throwing up or going to the bathroom—it just happens. I do give them factual information, but I do not want to raise their fears by concentrating on complicated breathing techniques or comfort measures. I'll always remember the time I was attending a woman in labor with her sixteenth baby. At one point in transition, she looked at me from where she was leaning up against a bureau and asked, "Should I do my breathing now?" I had to laugh and tell her, "You're the expert, you do whatever works." I haven't seen many Amish women use breathing techniques that anyone taught them. Almost without exception, my mothers tell me that giving birth wasn't hard at all.
— Anon.
Midwifery Today E-News readers may be interested in an update on the recent work of MOMS (Midwives on Missions of Service) and our nonprofit, dedicated to improving maternal/child health and maternity outcomes through education and service. We do this through service projects and our school, the International School of Traditional Midwifery.
MOMS has been invited to Sierra Leone by Women for Women of Sierra Leone and the Minister of Health. We have been assigned the Jawi "chiefdom" which is a region of villages in the eastern part of the country near Liberia. We will be going over in December to do a needs assessment. When we come back, we will begin to write a custom curriculum based on those needs. The literacy rate for women in Sierra Leone is under 30% so we will be looking at teaching methods that are culturally appropriate and effective. We are particularly excited because they want us to train the midwives in homebirth.
Sometime in 2007 we will return to Sierra Leone and begin to implement our program as well as work side by side with the Sierra Leonean midwives to improve their infant mortality and maternal morbidity rates which are some of, if not the, worst in the world. We anticipate that this will be a project that will last for several years until we can turn over the training to midwives there. It will take a lot of support and resources from our circle of supporters here in the US so we will be doing a lot of fundraising and gathering of supplies.
— Sudy Storm
[Editor's Note: To learn more about MOMS and how you can help: http://www.globalmidwives.org/ ]
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Use theatre for social change! BOLD is a global movement to make birth mother-friendly. Join our online book club or organize a BOLD performance in September 2007. Visit: http://www.birththeplay.com/bold/bold.html
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Midwifery Today: Each One Teach One!


text:
Another leading UK retailer has significantly discounted the Wii U.
Amazon has cut £50 off both the Wii U 32GB Premium Black machine and the 8GB Basic Pack, meaning they now retail at £249 and £199 respectively.
Also of note is the surprisingly low trade-in prices Amazon are offering to pay consumers who wish to offload their machines. It will buy a Premium for just £68.50 and the Basic for £55.
Retailer Asda revealed similar Wii U discounts earlier this month.
It remains unclear whether these are retail-led promotions designed to shift stock or instead officially sanctioned price reductions from Nintendo UK.


text: AFL-CIO wants Congress to say no to cuts to Medicare, Medicaid By Paul J. Nyden December 1, 2012 Story Share CHARLESTON, W.Va. -- National and state leaders of the American Federation of Labor and Congress of Industrial Organizations want Congress to let the George W. Bush tax cuts for the top 2 percent of all Americans expire. Labor leaders also want Congress to "say no to benefit cuts to Medicare, Medicaid and Social Security."The annual financial benefits coming into West Virginia from each of these programs include: $5.7 billion from Social Security, $3.5 billion from Medicare and $2.4 billion from Medicaid.The AFL-CIO released a new state-by-state study last week, detailing how many Americans would be impacted if Congress cuts benefits in these programs.Information nationally, and for all 50 states, can be found at: www.aflcio.org/StateFactSheets.Nationally, 55.4 million people receive $725 billion a year from Social Security benefits, while 48.7 million receive $541 billion for health coverage from Medicare and 64.4 million receive $355 billion for health coverage from Medicaid. These benefits provide a "critical lifeline" for West Virginians today:443,911 West Virginians receive monthly Social Security checks, including 93,663 workers with disabilities and 41,030 children.373,450 get health-care coverage from Medicare.416,858 get health-care coverage from Medicaid, including 199,023 children and 41,741 senior citizens.Increasing the eligibility age from 65 to 67 for Medicare would "substantially increase total health-care costs, with the burden falling on individuals, employers and state governments," the AFL-CIO study states.Those extra costs would be twice the net savings the Medicare age increase would give the federal government, according to an August 2011 study by Paul N. Van de Water published by the National Center on Budget and Policy Priorities, based in Washington.The AFL-CIO study also criticizes the impacts the Bowles-Simpson plan, supported by many members of Congress, would have on Social Security benefits. The proposed changes would cut the cost-of-living adjustment by 0.3 percent a year for all current and future Social Security beneficiaries. By the time retired workers reach 80, those cuts would amount to 5.1 percent of benefits received today, a loss of $852 a year.The changes would reduce benefits for "medium earners" by more than $2,875 a year, when Bowles-Simpson is completely phased in."Social Security has never added a penny to the deficit and should not be part of any deficit reduction negotiations," the AFL-CIO study points out.The AFL-CIO also supports "scrapping the cap."The cap exempts Americans from paying any Social Security taxes on annual earned income over $110,100 in 2012. The AFL-CIO wants all earnings to become subject to Social Security payroll taxes."High earners should contribute the same percentage of their income to Social Security as everyone else," the study states. Richard Trumka, president of the national AFL-CIO, said, "Working people, jobless people and retirees, who just voted for a middle-class economy [in last month's presidential election], shouldn't have to sacrifice their health care and retirement security so that the richest 2 percent can continue getting more tax breaks."It's time to protect Social Security, Medicare and Medicaid benefits that support our working families. It's time to eliminate tax breaks for the richest 2 percent. That's fair, reasonable, and good public policy."Two weeks ago, the Economic Policy Institute released a statement, signed by more than 300 economists and social insurance experts, opposing efforts to reduce annual cost-of-living adjustments that increase Social Security benefits.Based in Washington, EPI is a nonprofit, nonpartisan think tank created in 1986 to broaden economic policy discussions to include the needs of low- and middle-income workers.The oldest beneficiaries, who are often the poorest beneficiaries, and people who receive disability benefits for more than 20 years would see the largest cuts.The EPI argues statistical analyses based on spending patterns by the general population, which are used to calculate COLAs, are likely to "understate the impact of cost increases faced by Social Security beneficiaries, because seniors and disabled people spend a greater share of their incomes on out-of-pocket medical expenses than do other consumers."In recent decades, health costs have risen dramatically faster than overall inflation, the EPI adds.Reforms advocated by the AFL-CIO study include reining in the costs of health-care growth, making the health-care system itself more cost-effective, promoting the rights of workers to bargain collectively for wages and benefits and moving manufacturing plants back to America.Reach Paul J. Nyden at firstname.lastname@example.com or 304-348-5164. Story Share Story Share Trending Now 1 Facebook founder visits Cabin Creek Health Systems 2 Teen pleads guilty to voluntary manslaughter in Oakes Field shooting 3 Safety shutoff disabled prior to June coal-mining death, report says 4 Huggins, WVU tap South Florida hoops talent 5 New company planning $73M synthetic fuel plant in Greenbrier County Vandalism reported at Sutton Lake playground Previous Story Manchin discusses Senate vote on Afghan war resolution Next Story


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BP Comment Quick Links
|Strength of Schedule Report
November 28, 2012
The Lineup Card
9 Off-Season Moves That Excited Us Most as Kids
1. Pirates Acquire RHP George "Doc" Medich at the 1975 Winter Meetings
Medich had an outstanding rookie season with New York in 1973 when he went 14-9 with a 2.95 ERA in 34 games, 32 of which were starts. In 1974, he won 19 games—remember, wins were the accepted measurement of a pitcher's effectiveness back in the unenlightened era—and pitched 279 2/3 innings. He slipped to 16-16 in 1975, but the Pirates were sure the 27-year-old was just coming into his prime and ready to help front their rotation. Sadly, it didn't work out; he was 8-11 with a 3.52 ERA in 1976, then dealt to the Oakland Athletics in spring training the following year as part of a 12-player trade in which the Pirates gave up an outfielder of considerable promise named Tony Armas and got back Phil Garner. The most notable moment of Medich's career with the Pirates came on Opening Day at Veterans Stadium in Philadelphia, when he jumped into the stands and saved the life of a man having a heart attack. That was certainly more important than anything he ever did on the field during an 11-year career that was spent with seven teams. However, from a baseball standpoint—and an 11-year-old kid standpoint—he was a big-time disappointment. —John Perrotto
2. Indians Sign "Black" Jack McDowell Prior to the 1996 Season
I remember that when it was all done, the deal was seen as a bust. McDowell went 13-9 in 2006 with a 5.11 ERA. In retrospect, his peripherals weren't horrible (4.30 FIP), but they were not Cy Young-worthy, either. In 1997, McDowell got hurt, demoted to the bullpen, and never really surfaced again. By 1999, he was out of baseball. It was a lesson in the realities of pitching. As a Cleveland fan and a teenager, I believed in the magic of "knowing how to win" because of those 20-win seasons. I didn't appreciate that a pitcher is a risky signing no matter what, because they get hurt... just because they are pitchers. I was in high school at the time, which is when you discover that life doesn't work in magical ways, no matter how much you want it to. Jack McDowell was just one of those lessons on how baseball will break your heart. —Russell A. Carleton
3. Yankees Trade Jeff Weaver to the Dodgers
However, what left the worst taste in my mouth was his World Series performance. Though Weaver hadn't pitched in 11 days, manager Joe Torre brought in the northpaw during a tied game. After emerging from one inning unscathed, Torre pressed his luck and sent Weaver out for a second inning of work. He promptly gave up a game-winning walk-off home run.
I hoped and prayed that the Yankees would trade Weaver over the offseason, regardless of the return. My wish was granted. In December 2003, the Yankees traded Weaver, Brandon Weeden, Yhency Brazoban, and cash to the Los Angeles Dodgers for Kevin Brown. As it turns out, I owe my thanks to my colleague, Dan Evans, who was the general manager of the Dodgers at the time. Brown proved to be incredibly fragile and a hot head who broke his non-pitching hand punching a clubhouse wall during a September loss to the Orioles, but his inability to stay healthy primed me for the American Idle era. And credit where credit is due: Weaver notched 220 innings and allowed 219 hits, good for a 3.79 FIP and 3.6 WARP, for the 2004 Dodgers. But I salute you, Dan, for ending Jeff Weaver's Yankees tenure. —Stephani Bee
4. Andre Dawson's Blank Check
But the 1986-87 offseason, was the year of collusion. And that, coupled with the Tribune Company's unwillingness to increase their payroll (read: participation in the conspiracy), Dawson remained unsigned. Despite his near-frantic pleading.
As a 10-year-old, I didn't understand the dollars and cents; I just thought that Cubs general manager Dallas Green was a fool. Who could possibly think the slugging Dawson, a force at the plate, on the basepaths, and in the outfield was worse than presumed starter Brian Dayett? How could Green, who in three years had done what no Cubs GM had in nearly four decades—put a team in the playoffs—be so wrong?
Dawson was unsigned in March 1987. But rather than biting the bullet and returning to Montreal while sitting out until May, like teammate Tim Raines was doing, Dawson pressed the Cubs. The outfielder and his agent, Dick Moss, showed up in Cubs spring training offering a blank check to Cubs ownership. "Name you're price, we'll sign" was the message.
So the Cubs gave Dawson $500,000. Dawson hit 49 homers and won the MVP that year on a typical Cubs team that faded in the final two months. But here was Dawson, a star who wanted to play for my team.
I'm not really a Cubs fan anymore. I don't have an allegiance. I love good stories and am lucky enough to talk to many current and former ballplayers as part of my job. I always get nervous when I talk to, or meet, Andre Dawson. He was my favorite player growing up. Still is, actually, because despite the fact everyone tried to stonewall him, he got what he wanted in the end. He chose my team, more than they chose him. And I loved every minute of it. —Mike Ferrin
5. Red Sox Sign Manny Ramirez Prior to the 2001 Season
Over seven-and-a-half seasons in Boston, Ramirez hit .312/.411/.588, remarkably similar to his numbers in Cleveland. In the early part of his career as a Red Sox, he became symptomatic of what was wrong with the Dan Duquette administration. Later, he was a vital cog in two Boston world championships. Ramirez's time with Boston certainly had its turbulence, but the end result of seven All-Star appearances, seven top-10 MVP finishes, and the aforementioned two World Series wins make it difficult to argue the contract didn't return value. Many times—more than we'd probably like to imagine—the excitement generated by big free-agent signings goes unrequited. In this instance, the Red Sox got more than they paid for, and those of us who cheered the signing didn't do so in vain. —Matthew Kory
6. Giants Sign Moises Alou Prior to the 2005 Season
I didn't care that Alou was 38 years old. He was a marquee player coming off a year in which he smacked 39 home runs with 106 RBI. He was a heart-of-the-order bat that would join Barry Bonds in carrying the Giants to the postseason, and, hopefully, a World Series title. Obviously this isn't what transpired, but at the end of December 2004, it was very real in my imagination. —Josh Shepardson
7. Giants Sign Mark Portugal Prior to the 1994 Season
8. Dodgers Sign Dave Goltz and Don Stanhouse Prior to the 1980 Season
a) Goltz had won 20 games for the Twins in 1977.
Goltz went 7-11 for the Dodgers. He had a 5.68 ERA at the All-Star break and lost his spot in the rotation. He fared a little better in the second half before getting shelled by the Astros in Game 163, when he got the start over rookie left-hander Fernando Valenzuela. After doing little of consequence the following season, Goltz was released on April 27, 1982.
Stanhouse didn't last as long. He pitched just 25 innings for the Dodgers, most of them terrible. Among other things, he walked 16 while striking out five. He'd walked 51 while striking out 34 a year earlier, so this was nothing new for Stan the Man Unusual.
My view of free-agent signings probably has been warped by the Dodgers' acquisitions of Goltz and Stanhouse. If I haven't gotten over them after 33 years, I doubt I ever will. —Geoff Young
9. Kenny Landreaux
Which leaves Kenny Landreaux. The 1980 Dodgers lost a Game 163 play-in to the Astros (a game started by the bust Goltz instead of the rookie Fernando Valenzuela), and it's not unreasonable to think that they would have gotten over the hump with a better center fielder than Rudy Law, a 23-year-old burner who stole 40 bases but hit an offense-deadening .260/.306/.302, with virtually all of his plate appearances coming in the top two spots in the lineup. A change was needed, but it wasn't until the Dodgers acquired Landreaux from the Twins for Mickey Hatcher (a futility infielder favorite) and two other players during spring training in 1981 that they got one.
I knew Landreaux because of his baseball card. I could even, in that primitive era, see that his .281 average, seven home runs, and 62 RBI were superior to Law's numbers (with one homer and 23 RBI), to say nothing of a fu manchu mustache and sideburns that would have done a Civil War general proud. When we heard the news of the trade, my dad asked me for a full report after his pre-dinner nap. I went to my room, pulled out my Who's Who in Baseball 1981, wrote out his basic stats on a notepad as well as whatever I could find via my my stack of Sports Illustrateds (including this feature): the centerpiece of a trade for Rod Carew in 1979, he had put together a 31-game hitting streak the following year en route to an All-Star appearance. I wasn't actually writing paragraphs, and the World Wide Web hadn't been invented yet, but in a way, it was my first blog entry.
For all of my excitement, Landreaux rarely lived up to his promise as a Dodger, as he developed cocaine problems and retained his job more due to organizational inertia than anything else. But even in the strike-torn 1981 season, when he slumped to .251/.297/.367, he did haul in Bob Watson's fly ball to seal the Dodgers' first world championship of my lifetime—ample reward for my excitement. —Jay Jaffe
14 comments have been left for this article.
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For me it was 1977, the year Reggie Jackson signed with The Yankees and "Mr. October" was born.
Nov 28, 2012 06:04 AM
December 5th, 1990. Pat Gillick sends Fred McGriff and Tony Fernandez to the San Diego Padres for Joe Carter and Roberto Alomar. http://www.nytimes.com/2010/01/06/sports/baseball/06trade.html?_r=0
Nov 28, 2012 07:36 AM
1990 KC Royals, coming off a 90-win season signed Mark and Storm Davis. Add in a fading Brett and 'Bo Knows' baseball and ... they won 75 games.
Nov 28, 2012 07:43 AM
"In the early part of his career as a Red Sox, [Manny Ramirez] became symbiotic of what was wrong with the Dan Duquette administration." That's kind of an awesome typo.
Nov 28, 2012 08:04 AM
Angered over the loss of Burt Hooten, and the dismantling of the Cubs of my youth (Santo to the White Sox, Williams to the As, Fergie to Texas, Kessinger to St. Louis, Hundley and Beckert to San Diego), the Dawson signing remains one of the great mysteries of my lifetime. I agree - he WANTED to be a Cubs player. That was so cool to me. He was there for Boys of Zimmer in 1989, so he was rewarded (somewhat) for coming to Wrigley.
Nov 28, 2012 08:42 AM
For me it was when the White Sox signed Albert Belle. I was in 4th grade and the White Sox were usually bad and losing divisions to the Indians. I remember hearing the news on WWF Raw (hey I liked wrestling at the time) and ran to my dad to tell him. He didn't believe me because of the source.
Nov 28, 2012 10:39 AM
Fun read. Nice to know your writers can be "homers" from time to time too. BTW, pretty sure it should read "symptomatic" not "symbiotic" in Matthew Kory's piece on Manny.
Nov 28, 2012 11:16 AM
Gregg Jefferies, 1994! The only stats I knew of as a 12 or 13 year old were the top 20 or so batting averages in the league, as listed in the Lehigh Valley's newspaper of record, the "Morning Call". After seeing Jefferies listed at or near the top once a week for a couple years, it was unbelievable to see him join the Phils.
Nov 28, 2012 11:45 AM
For me it was the Dodgers of 74 acquiring the toy cannon Jimmy Wynn. The fans took to him and he had a great year although I don't have the stats to back that up. Doesn't come close to the Lakers acquiring Kareem from Milwaukee shortly after that but that is for another board.
Nov 28, 2012 11:47 AM
Dave Scott
I would like to suggest the Indians' signing of Wayne Garland to a 10-year deal worth (gasp!) $1.3 million. In today's money it might have been worth it. He did have one decent season.
Nov 28, 2012 12:39 PM
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Dr. Sandro Parisi MD
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Dr. Sandro Parisi, MD is a Doctor primarily located in El Paso, TX, with another office in El Paso, TX. He has 22 years of experience. His specialties include Diagnostic Radiology. Dr. Parisi is affiliated with Providence Memorial Hospital, Sierra Medical Center and Sierra Providence East Medical Center. He speaks English.
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POLICE are investigating an incident where two men were assaulted in Clacton.
Officers were called to Orwell Road in the early hours of Saturday after reports of a disturbance.
Once they arrived they found two men being treated by the ambulance service.
A 21-year-old man from Wickford was treated for a fractured jaw, broken nose and several lost teeth after he was punched and fell against a wall.
The other man, a 25-year-old from Chelmsford was knocked unconscious and taken to hospital to be checked out. He was later discharged.
The suspect can only be described as a white man wearing a ripped white t-shirt and black jeans.
Anyone with information about the circumstances leading up to the incident or any other information should contact DC Luke Howard at Clacton CID on 101.


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NetWellness is a global, community service providing quality, unbiased health information from our partner university faculty. NetWellness is commercial-free and does not accept advertising.
Wednesday, September 20, 2017
Mouth Diseases
Sore Mouth
hi i am 23 and have stopped smoking a week ago. i have got dry lips and on the inside they are sore also my soft palate is yellow with little red dots. could you pls tell me what this could be thanks.
Congratulations on stopping smoking! This is an important step in improving your oral health. Without examining you, it would be impossible to say exactly what this is. Although nothing that you describe sounds serious, if you are concerned, you might want to make an appointment to see your dentist or an oral pathologist for evaluation. Again, congratulation on stopping smoking!
John R Kalmar, DMD, PhD
Clinical Professor of Pathology
College of Dentistry
The Ohio State University


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Jointstrong Intervention for Juvenile Arthritis
- Full Text View
- Tabular View
- Study Results
- Disclaimer
- How to Read a Study Record
|Juvenile Arthritis
|Behavioral: CD-ROM Behavioral: Wait-list Control Group
|Study Type:
|Study Design:
|Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
|Official Title:
|Jointstrong Intervention for Juvenile Arthritis
- Pain [ Time Frame: weekly for 12 weeks ]Pain intensity on a 0 to 10 visual analog scale with 0 being no pain and 10 being worst possible pain.
- Mood and Stress [ Time Frame: weekly for 12 weeks ]
- Quality of Life [ Time Frame: weekly for 12 weeks ]
|Study Start Date:
|April 2009
|Study Completion Date:
|May 2011
|Primary Completion Date:
|March 2011 (Final data collection date for primary outcome measure)
|Assigned Interventions
|Experimental: CD-ROM-treatment
Behavioral: CD-ROM
Treatment Group will continue to follow their treating rheumatologist's recommendations and prescriptions. The program will contain information on the multiple components of pain (the "pain puzzle") as a treatment rationale and will then teach children to use cognitive-behavioral techniques for pain management. The information will be presented via visual displays, narration, and interactive menus. Children will be able to navigate through the different lessons at their own pace and will be required to take simple quizzes to assess their learning. Various passwords and homework assignments are embedded within the program to ensure that children are going through the material.
|Active Comparator: Wait-list Control Group
Behavioral: Wait-list Control Group
Children in the control group will continue to follow recommendations and prescriptions by their treating rheumatologist. After an 8-week wait-list control condition that involves measurement phases identical to those of the Jointstrong Treatment Group but no Jointstrong treatment, the children in the control group will enter the Jointstrong program and will then have the same immediate post-treatment measures that the Treatment Group received. The Control Group will not, however, have the Treatment Group's 12-week follow-up phase.
Detailed Description:
If your child is eligible and decides to participate in this study, this participation will last approximately eight weeks. Please refer to the table at the end of this consent form.
Your child's participation in this study will involve the completion of daily questionnaires during a one-week baseline period and a one-week follow-up period. These questionnaires will contain various questions about your child's arthritis and his/her ability to do various activities. The questionnaires will take approximately 15-30 minutes each week to complete.
Your child will be randomly assigned to complete one of two CD-ROM programs. One of the CD-ROM programs is a "control" program that contains educational information about arthritis and medical treatments and the other is the "treatment" program and contains the same educational information as the control program plus information on behavioral strategies for controlling symptoms of arthritis. Your child's participation in this study will involve working through one of these CD-ROM programs over a one-month period. Your child will also continue to receive medical treatment from the rheumatologist treating your child for arthritis. The CD-ROM programs involve working through developmentally appropriate lessons on the nature of arthritis and how to treat it. The CD-ROM programs are divided into weekly "modules" and are designed to be completed within four weeks. Lessons take an average of 15 minutes to complete (plus "homework"), and there is an average of 4 lessons to complete each week.
Your participation in this study will involve the completion of questionnaires and helping your child understand any parts of the study that he or she does not understand.
|Ages Eligible for Study:
|8 Years to 12 Years (Child)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria. Patients recruited for this study will meet the following inclusion criteria: (a) are 8-12 years of age; (b) have a diagnosis of JA by a pediatric rheumatologist using established criteria, and (c) have JA-related (joint) pain occurring on an average of at least once per week by patient report [9]. Participants in the age range 8-12 years will be recruited because the intervention will be tailored to children (future studies will involve creating and testing a version of Jointstrong for adolescents). Although access to a home computer with a CD-ROM drive is required for the study, this will not be an inclusion criterion, and we expect the lack of access will be rare, as our pilot data on 37 children with headaches found that only 2% (1 child) did not have adequate home computer access [15]. So as not to exclude the few children without access who otherwise qualify for the study, we will lend laptop computers to these children. All children meeting symptom inclusion criteria will therefore be able to use the adjunctive CD-ROM programs in a home setting.
Exclusion Criteria. Patients will be excluded from the study if (a) their parents or rheumatologist report they have been diagnosed with a mental health condition or they are receiving concurrent psychotherapy; or (b) their 14-day baseline pain diaries indicate they have pain, on average, less than one day per week; or (c) they do not speak English.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01166750
|United States, Kansas
|University Of Kansas Medical Center
|Kansas City, Kansas, United States, 66160
|Principal Investigator:
|Michael Rapoff, Ph D
|University of Kansas Medical Center
|Responsible Party:
|Michael Rapoff, Ph.D., Professor, University of Kansas Medical Center Research Institute
|ClinicalTrials.gov Identifier:
|NCT01166750 History of Changes
|Other Study ID Numbers:
|Study First Received:
|July 19, 2010
|Results First Received:
|September 24, 2012
|Last Updated:
|May 30, 2013
Additional relevant MeSH terms:
Arthritis, Juvenile
Joint Diseases
Musculoskeletal Diseases
Rheumatic Diseases
Connective Tissue Diseases
Autoimmune Diseases
Immune System Diseases
ClinicalTrials.gov processed this record on September 19, 2017


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HAINES Watts have won an accountancy excellence award for the third year running.
The firm of accountants, based in Sarum Hill, won the Accountancy Firm of the Year – SMEs, at the annual FDs' Excellence Awards.
It comes after the firm won Auditor of the Year for the past two years.
The awards recognise the service providers that support Britain's finance community and are based on the results of an annual survey in which financial directors and financial decision-makers recorded their opinion.
The prestigious awards ceremony was held in Grosvenor Square, London and was hosted by Real Business in association with the Institute of Chartered Accountants in England and Wales (ICAEW), supported by the Confederation of British Industry (CBI).
Haines Watts beat stiff competition from a number of other UK firms. Barry Potter, who is a partner at Haines Watts in Basingstoke, said: "It's great to see Haines Watts win such a prestigious award. This type of award really matters to us because it's voted for by business people and not by an academic panel of experts.
"It's fantastic that we are the first firm ever to have won an award in three consecutive years.
"We are proud of all of our staff, who do an outstanding job for our clients day to day and who have contributed towards us winning this award."


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What is it?
The 1Sheeld is an Arduino shield that allows for smartphone sensor information to be used with an Arduino device.
The Verdict:
1Sheeld to rule them all! The 1Sheeld for Arduino is a must have component for beginners and advanced users alike. It's easy to use, easy to setup, and arms most Arduinos with a bevy of prototyping tools at their disposal. The bottom line is if you own a compatible Arduino and an Android device you should buy a 1Sheeld.
Anyone who's ever spent any amount of time with an Arduino knows of its seemingly unlimited potential. Arduino has an extremely large support community and because it's open source hardware, the number of ways you can expand are only limited by imagination. Buy an Arduino, and if you're anything like me you'll feel compelled to purchase many of the available shields add-on modules just to see what new possibilities exist. The cost of Arduino shields seem to increase based on their usefulness, so often times many of the cheaper shields you buy first simply get left out of any design when it comes to protect implementation time. What if "1 shield" could effectively replace the pile of shields you'd normally purchase during prototyping? Meet the 1Sheeld.
1Sheeld is a prototypers dream add-on. Using an Android device running 2.3+ and an awesome 1Sheeld app, your smartphone becomes your Arduino shields. 1Sheeld's job is to communicate between the Arduino and the Android. Using the built-in HC-06 Bluetooth module, 1Sheeld allows any available sensor in your smartphone to become a virtual shield, so that the sensor data can be used in Arduino sketches.
The 1Sheeld can serve as a GPS shield, Wifi shield, and most any other shield available today. In addition, it replaces smaller hardware components like LEDs, buttons, and buzzers. Want to design a sketch using a gamepad or keyboard? 1Sheeld makes this easy. Email, SMS, Facebook, and Foursquare implementation is a breeze thanks to the 1Sheeld.
With the power and flexibility the 1Sheeld affords, its easy to see an incredibly complex Android control app. I was frankly amazed at how clean and easy to use the app is. Upon first running the app, you're presented with a short tutorial, then a scan button that searches for 1Sheeld devices in the 30 foot range. Once a 1Sheeld is found, pairing is a single tap process. From there, the UI shows all of the available sensors the app has in a simple and clean manner. You can select which of the various sensors you would like to enable, and any sensors not available to the Android device are blocked immediately via toast notification. Once you've selected the sensors you want to utilize, a single button presents a screen where the selected sensors are displayed with their various values. The entire app interface is fluid, fast, and organized. There's even an included plugin for the powerful automation Android app Tasker. The available 1Sheeld library for Arduino is also top notch, with several example sketches for the various sensors the shield provides.
The 1Sheeld is designed to attach to the standard Arduino shield form factor. Connecting to an Uno or Mega is very easy. Compatibility issues do exist with Arduino's without the standard shield form factor. The 1Sheeld is also a pass-through shield, allowing access to the Arduino's input/output pins.
The Positive:
� Powerful, flexible platform
� Terrific Android app
� Arduino library all but eliminates sketch implementation issues
� Easy learning and setup process
� Standard shield form factor
� Tasker support
The Negative:
� No current Apple support
� Wont connect to Arduino's without the standard shield form factor.
The Verdict:
1Sheeld to rule them all! The 1Sheeld for Arduino is a must have component for beginners and advanced users alike. It's easy to use, easy to setup, and arms most Arduinos with a bevy of prototyping tools at their disposal. The bottom line is if you own a compatible Arduino and an Android device you should buy a 1Sheeld.


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Goldbaby has recorded some more drum machines to tape. The new Vol.3 sample pack is $29. He has some good free packs on his site too. Having a few Ableton Impulse patches created out of these nicely recorded machines is handy.
"Drum Machines used: RZ-1, TR-55, XD-5, MFB-522, DDM-110, DDM-220, DPM-48, RX-21L, R-100, ED-10, PB-300 and the DSM-1. The Tape machines used: Otari MX5050 1/4″, Rolla 77 valve mono 1/4 inch, and the Hitachi Cassette deck. Plus the UBK Fatso was also used!" – goldbaby.co.nz
For audio samples and more info: goldbaby.co.nz


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chandrafabian wrote:Virgo wrote:If you read the whole section on Panna you will see that soil and the first two purifcations of the trunk must come before that. Also, you have misunderstood that section, in and of itself, nevermind the fact that the rest of the soil and trunk are not present in Mahasi and Goenka method.
Be well,
Dear Kevin,
First thing first, do you agree there is Arahant without Jhana?
And please specify one by one the soil you need to know about, in Mahasi method.
Hi Chandrafabian,
The Visuddhimagga clearly states that one can attain Arahant without jhana, chandrafabian.
Please read the thread. I listed all the topics in the soil already.
Thank you for your question.


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Vail Cascade SpringFest is Far Out Fun
Spring is almost here and Vail Cascade is spreading Peace, Love and great Deals at our first annual Cascade SpringFest. Book a stay between March 7th and May 9th and enjoy everything that makes spring so special in Vail. Plus, KIDS EAT AND STAY FREE!
Kids of all ages will be doing the "Hustle" up the hill as they groove on a variety of Vail activities and special offers, including poolside parties, concerts, KidVenture camp, yoga workshops, wine tastings, arts & crafts, and more! For a complete listing of Cascade SpringFest event information and deals, visit www.vailspringfest.com.


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It's An Aeolian Harp Thing Sleeveless
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Sku: SL1BL0000004182424240003WHLG00000


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Do Liam Gallagher's Cryptic Tweets Spell Oasis Reunion?
British version of Charlie Sheen Liam Gallagher has been teasing Oasis fans with the prospect of a reunion on Twitter. Over the course of two hours, he spelled out Oasis, one tweet at a time. He capped off this bit of mystery by putting all the letters together in one tweet.
Since then, the Twitterverse has been atwitter with speculation as to what the singer's tweets could mean. The most popular theory is that Oasis will play the Glastonbury music festival this June.
Shortly after Liam's spelling bee, betting website Paddy Power tweeted:
Betting now suspended on #Oasis to play Glastonbury.
— Paddy Power (@paddypower) April 24, 2014
Oasis fans immediately started expressing their excitement over the possibility of seeing Oasis take the stage again.
"Mum, dad, brother, the dog, and my car are going on eBay if Oasis reform. Who needs that that when you have Noel and Liam back together?" asked one fan. "Michael Eavis was asked whether or not the final headliner had been booked, he answered definitely maybe," said another.
Last year, though, Liam said he wouldn't consider reuniting with his brother Noel for less than £30 million. But former Oasis guitarist Paul 'Bonehead' Arthurs told NME in January that he'd still play with the band. And he feels that Liam would be game too.
"If someone said, 'Here's a field, here's a stage and here's 200,000 people,' I'm sure Liam would jump up and do it, and I don't think it would even take anyone offering him a massive bankroll of money," Arthurs said. "He'd do it because that's what he loves, that's his passion."
He went on to say, though, that he didn't think Noel would be as eager to get back onstage with his brother. Until we find out exactly what the deal is, here's a video to remind us why this prospect is so exciting.
Subscribe to Diffuser.fm on


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Hello all,
Recently just bought a cheap tablet to watch my games on and the video player is unable to initialize. I have also seen that the Nexus 7 won't support it either. I would like to return this one and find one that will play league pass with video. Open to any recommendations.


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NetWellness is a global, community service providing quality, unbiased health information from our partner university faculty. NetWellness is commercial-free and does not accept advertising.
Saturday, September 23, 2017
Dental Anesthesia
Injection Novocain I Felt an Electrical Zap?
What was the electrical zap I felt when my dentist injected the Novocain? The cavity was filled in my lower jaw. She said it got close to the nerve. I still feel a tingly feeling in my lower lip?
When the dentist places the local anesthetic for the lower jaw, he or she tried to get in the area of a specific nerve. If the dentist does this just perfectly, the needle can brush by the nerve causing the electrical shock you felt. Most of the time, the nerve remains numb for a day or two but it can be longer.
If the tingling is still present several days after the injection, you should contact your dentist to let him or her know that you are still experiencing some numbness. In the vast majority of cases, there are no long lasting symptoms.
Steven I Ganzberg, SB, DMD, MS
Formerly, Clinical Professor of Dentistry
College of Dentistry
The Ohio State University


text: President Obama is providing 20 F-16 fighter jets to Egypt, which brings its total to 260; and 200 M1A1 Abrams tanks, bringing its total to 1,200. These arms are offensive weapons that could be used against Israel or resold to other Arab countries or organizations for use against Israel.Given the instability in Egypt and the ascendance of Mohammed Morsi, a devout member of the Muslim Brotherhood, to the presidency in Egypt, we should not be building up Egypt's armed forces. The Muslim Brotherhood is committed to the destruction of Israel and the imposition of Sharia (Islamic) law in Egypt, other countries in the Middle East and throughout the world.Israel is the only friendly and trustworthy country standing in the Middle East. It needs to be able to purchase U.S. arms, and needs our diplomatic and moral support.Donald A. Moskowitz Londonderry, N.H.


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Thiotepa (Thioplex®)
Pronounced: thigh-oh-TEP-uh
Classification: Alkylating Agent
About Thiotepa (Thioplex®)
Thiotepa exerts its anti-cancer affect by a process called alkylation. Alkylation damages the DNA of cells, leaving them unable to divide. Without cell division, the tumor cannot grow and spread.
How to Take Thiotepa
Thiotepa can be given in several ways, including: into a vein (intravenous), into the bladder (intravesicular), into the spinal fluid (intrathecal), and into the abdominal cavity (intraperitoneal). The dose is dependent on your size, the method of administration, and the type of cancer being treated. During treatment you will have lab work drawn at least once a week to monitor your blood counts.
Possible Side Effects of Thiotepa
There are a number of things you can do to manage the side effects of thiotepa. Talk to your doctor or nurse about these recommendations. They can help you decide what will work best for you. These are some of the most common side effects:
Low White Blood Cell Count (Leukopenia or Neutropenia)
White blood cells (WBC) are important for fighting infection. While receiving treatment, your WBC count can drop, putting you at a higher risk of getting an infection. You should let your doctor or nurse know right away if you have a fever (temperature greater than 100.4), sore throat or cold, shortness of breath, cough, burning with urination, or a sore that doesn't heal.
Tips to preventing infection:
- Washing hands, both yours and your visitors, is the best way to prevent the spread of infection.
- Avoid large crowds and people who are sick (i.e.: those who have a cold, fever or cough or live with someone with these symptoms).
- When working in your yard, wear protective clothing including long pants and gloves.
- Do not handle pet waste.
- Keep all cuts or scratches clean.
- Shower or bath daily and perform frequent mouth care.
- Do not cut cuticles or ingrown nails. You may wear nail polish, but not fake nails.
- Ask your doctor or nurse before scheduling dental appointments or procedures.
- Ask your doctor or nurse before you, or someone you live with, has any vaccinations.
Low Red Blood Cell Count (Anemia)
Your red blood cells are responsible for carrying oxygen to the tissues in your body. When the red cell count is low, you may feel tired or weak. You should let your doctor or nurse know if you experience any shortness of breath, difficulty breathing or pain in your chest. If the count gets too low, you may receive a blood transfusion.
Low Platelet Count (Thrombocytopenia)
Platelets help your blood clot, so when the count is low you are at a higher risk of bleeding. Let your doctor or nurse know if you have any excess bruising or bleeding, including nose bleeds, bleeding gums or blood in your urine or stool. If the platelet count becomes too low, you may receive a transfusion of platelets.
- Do not use a razor (an electric razor is fine).
- Avoid contact sports and activities that can result in injury or bleeding.
- Do not take aspirin (salicylic acid), non-steroidal, anti-inflammatory medications (NSAIDs) such as Motrin®, Aleve®, Advil®, etc. as these can all increase the risk of bleeding. Unless your healthcare team tells you otherwise, you may take acetaminophen (Tylenol).
- Do not floss or use toothpicks and use a soft-bristle toothbrush to brush your teeth.
Nausea and/or Vomiting
Talk to your doctor or nurse so they can prescribe medications to help you manage nausea and vomiting. In addition, dietary changes may help. Avoid things that may worsen the symptoms, such as heavy or greasy/fatty, spicy or acidic foods (lemons, tomatoes, oranges). Try antacids, (e.g. milk of magnesia, calcium tablets such as Tums), saltines, or ginger ale to lessen symptoms.
Call your doctor or nurse if you are unable to keep fluids down for more than 12 hours or if you feel lightheaded or dizzy at any time.
Fatigue is very common during cancer treatment and is an overwhelming feeling of exhaustion that is not usually relieved by rest. While on cancer treatment, and for a period after, you may need to adjust your schedule to manage fatigue. Plan times to rest during the day and conserve energy for more important activities. Exercise can help combat fatigue; a simple daily walk with a friend can help. Talk to your healthcare team for helpful tips on dealing with this side effect.
Decrease in Appetite
Nutrition is an important part of your care. Cancer treatment can affect your appetite and, in some cases, the side effects of treatment can make eating difficult. Ask your nurse about nutritional counseling services at your treatment center to help with food choices.
- Try to eat five or six small meals or snacks throughout the day, instead of 3 larger meals.
- If you are not eating enough, nutritional supplements may help.
- You may experience a metallic taste or find that food has no taste at all. You may dislike foods or beverages that you liked before receiving cancer treatment. These symptoms can last for several months or longer after treatment ends.
- Avoid any food that you think smells or tastes bad. If red meat is a problem, eat chicken, turkey, eggs, dairy products and fish without a strong smell. Sometimes cold food has less of an odor.
- Add extra flavor to meat or fish by marinating it in sweet juices, sweet and sour sauce or dressings. Use seasonings like basil, oregano or rosemary to add flavor. Bacon, ham and onion can add flavor to vegetables.
Loss or Thinning of Scalp and Body Hair (Alopecia)
Your hair may become thin, brittle, or may fall out. This typically begins two to three weeks after treatment starts. This hair loss can be all body hair, including pubic, underarm, legs/arms, eyelashes, and nose hairs. The use of scarves, wigs, hats and hairpieces may help. Hair generally starts to regrow soon after treatment is completed. Remember your hair helps keep you warm in cold weather, so a hat is particularly important in cold weather or to protect you from the sun.
Secondary Malignancies
There is a very low risk of developing leukemia or other type of cancer due to treatment with this medication, which can occur many years after treatment. This is most often associated with repeated treatments or high doses.
Skin Changes
Some patients may develop a rash, very dry or itchy skin. Use an alcohol free moisturizer on your skin and lips; avoid moisturizers with perfumes or scents. Your doctor or nurse can recommend a topical medication if itching is bothersome. If your skin does crack or bleed, be sure to keep the area clean to avoid infection. Your skin may darken. This tends to resolve after treatment. Be sure to notify your healthcare provider of any rash that develops, as this can be a reaction. They can give you more tips on caring for your skin.
Infusion-Related Side Effects
The infusion can cause a reaction that may lead to itching, rash, tightness in the throat and difficulty breathing. Reactions vary depending upon how the medication is given. Notify your provider of any changes in how you feel during the infusion.
Other Side Effects
- If you receive the drug in the bladder directly into your bladder, you may develop burning, irritation or bleeding when urinating. Drink at least 10 glasses of non-alcoholic fluids a day for a few days after treatment to decrease this effect. If you notice any bleeding, notify your healthcare team right away.
- Other side effects reported include dizziness, headache and blurred vision. Report these side effects to your provider.
This medication may affect your reproductive system, resulting in the menstrual cycle or sperm production becoming irregular or stopping permanently. Women may experience menopausal effects including hot flashes and vaginal dryness. In addition, the desire for sex may decrease during treatment. You may want to consider sperm banking or egg harvesting if you may wish to have a child in the future. Discuss these options with your oncology team.
Exposure of an unborn child to this medication could cause birth defects, so you should not become pregnant or father a child while on this medication. Effective birth control is necessary during treatment and for a period after treatment, even if your menstrual cycle stops or you believe you are not producing sperm. You should consult with your healthcare team before breastfeeding while receiving this medication.


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Blood flow
Debate and discussion of any biological questions not pertaining to a particular topic.
Moderator: BioTeam
8 posts • Page 1 of 1
Blood flow
Can anyone tell me in a relatively short sentance or paragraph, what happens to the flow of blood during exercise? Thank you
flow of blood
This is I can say....when we get exercise, our heart will beat faster because the blood needs more oxgen. so in order to make the blood get enough oxygen, Adrenaline hormone is working by enlarging the blood vine and stimulate the heart work by make it faster. As a result, our blood vines are larger and we get more sweats because more oxgen means more burning (oxydative) process.
thanks also
Yupz, you're welcome...
Mithril is right. In the process of cellular respiration, only 40% of the energy is lost through ATP, the rest is turned into heat. But humans are homeoterm organisms, our body temperature is constant. So the body solves that problem by sweating... As the sweat evaporates from our skin it cools our body. That is why you need to drink a lot of water when you are exercising
"As a biologist, I firmly believe that when you're dead, you're dead. Except for what you live behind in history. That's the only afterlife" - J. Craig Venter
So that's why they're called homeothermic, I just took the sat2 and that was one of the questions....which animal is homeothermic and has placenta.....thank god the only placental mammal there was "cow"
Living one day at a time;
Enjoying one moment at a time;
Accepting hardships as the pathway to peace;
I mean, because of the oxydative process when we exercise is getting faster, it produces heat as the result of the process..As you said, our oxydation process isn't perfectly efficient..it produces heat as a side matter. because of this heat that makes our body feel hotter then our skin try to release it by enlarge the pore and sweating (it's kinda like reduce the heat by using water). I think that why our body temperature is constant and of course because of that we need more water to replace it.
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Egyptian Galleries on-line
Artefacts from the Fitzwilliam Museum's Egyptian collection are displayed in Gallery 19 and Gallery 20 (museum floor plan). These web pages allow you to view the objects displayed and find out more about them from the records in the museum's on-line database.
Religion and Daily Life in Ancient Egypt
Cases 11 to 13 introduce the religious beliefs and practices of ancient Egypt, as well as those of foreigners living in Egypt. Christian and Islamic artefacts are also displayed in this section.
Death and Burial in Ancient Egypt
The objects in this gallery relate to ancient Egyptian burial practices from around 5000-4500 BC to the Roman period and beyond, including artefacts from Islamic and Christian (Coptic) Egypt.
People of Ancient Egypt
This gallery offers a chronological introduction to the people of Ancient Egypt. The earliest objects in the gallery, date to around 3050 BC. The displays end with Roman and later Egypt.


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The containers come in two cup (one pint) or four cup (one quart) sizes. Both sizes are marked on the side in one cup increments, which is something that's very handy when you have quarts of chicken stock in the freezer and you only need two cups. The lids screw on tightly and are interchangeable between the two sizes, which is another big plus for me. Finally, I love it that the containers nest into each other so they can be stored laying down in a drawer.
Does anyone else love these containers besides me? If so, I'd love to hear in the comments about how you've used them.


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Still going strong after five months!
Ashton Kutcher and Mila Kunis have recently been parading their relationship around NYC. The 34-year-old actor, still separated from Demi Moore, has been living with his onetime That '70s Show costar, 29, while she films The Angriest Man in Brooklyn in the city.
"He always had a thing for her," a source told Us Weekly. "It's a real infatuation."
On Sept. 17, the pair of five months fed each other brunch across the table at NYC's Philip Marie restaurant -- then cuddled up on a boulder for an extended smooching session in Central Park.
"They only saw each other," a witness said of the duo. "Nothing else seemed to matter."
While a source told Us that Kunis "isn't sure this will last," the Friends With Benefits actress is "going for it."


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Single Doors • Double Doors • Sliding Doors • French Doors
The Phantom door screen provides the utility of a conventional screen with none of the unsightly results. It is there when you need it, and not when you don't. No other door screen is as stylish, versatile and functional.
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For Folding Wall Systems & Large Openings
Infinity Screens allow you to add screens to folding wall systems and large openings without limitations on the span or width. The maximum number of panels is virtually unlimited, and any of the 3 ft. panels can be designated as an entryway.


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In Monday's column I laid out the case for a head-and-shoulders top to take hold after we turn the calendar into January. However, I noted that the market was not yet overbought, and that I expected some sort of oversold rally to develop this week for year-end. So I think it's too soon for me to do much complaining -- yet some of the statistics in Monday's rally were so glaring that I cannot sit quiet.
Let us begin with the number of stocks making new highs. If I thought they made for poor reading before Monday's rally, things didn't change much with Monday's climb. Here is the progression: On Nov. 29 the S&P 500 closed at 1416 with 163 new highs. Dec. 3 saw a higher intraday high than on Nov. 29, and new highs lagged with 149. Last week, on Dec. 11 and Dec. 12, the S&P closed at 1427 and 1428 respectively with 125 and 122 stocks at new highs, respectively. I think you can see the progression of higher highs in the S&P and fewer new highs in stocks.
I'll bet you, like me, expected a decent increase in new highs during Monday's rally. If so, you would have been disappointed, since there were a mere 79 stocks at new highs to coincide with it. That is half of what we saw Nov. 29, when the S&P was 14 points lower. If this statistic doesn't improve soon, these negative divergences will matter when the market is overbought again.
Then there is the breadth. On its own, Monday's number was OK -- not great. For the NYSE, it came in at 1050 with the S&P up almost 17 points. Last week the S&P was up almost half of that, with a gain of just 9 points and net breadth was at plus 1070. So we saw a "better" breadth day last week with the S&P up a bit more than half the number of points. Again, as with the new highs, this is not impressive. In fact, the cumulative advance-decline line made a marginal lower high Monday vs. last week. It is so marginal that we should not to fuss about it -- but it is the first time breadth did not keep pace.
As far as sentiment goes, folks certainly got giddy on Monday. The ISE call-put ratio registered at 289%. To show you how rare this, is I'm posting the chart that runs back to late 2009, circling just four times the ratio has gotten this high, with the two instances on the left side coming in much lower than the other couple of times. The two on the right side -- i.e. the most recent -- are Sept. 14 of this year and July 20, 2011. As a reminder, the Sept. 14 date was at the high marking the Fed announcement of more quantitative easing -- and July of 2011 was shortly before U.S. debt was downgraded and the market collapsed in August.
On the left side, those two circles were in 2010. The leftmost one was mid-April; the market made a high two weeks later, and the "flash crash" was three weeks after that. The next one over came in the middle of the summer of 2010, just as the S&P was about to give back an 8% rally.
I haven't included that clump of high readings seen in late 2010, since those are the ones that came in December, which is similar to the present in terms of seasonality. So you have a choice: Ignore the readings because they are in December -- or do not.
My sense is that the lack of new highs, the tepid breadth and the high ISE might not matter into year-end -- but that they all will matter come January, once the market gets overbought.


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budesonide (generic name)
It is used in the treatment of Crohn's disease and ulcerative colitis which are types of inflammatory bowel disease
(bue DES oh nide)
Table of Contents
Top Learning Centers(Recursos en Español)
Where should I keep my medicine?Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep container tightly closed. Throw away any unused medicine after the expiration date.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.


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CHINO HILLS – The city's all-mail ballots will be sent out this week.
A special election needs to be held to replace Councilman Bill Kruger who submitted his letter of resignation Sept. 4.
An all-mail special election on March 5 will be held to fill the former councilman's seat.
The ballots must be received by the San Bernardino County Elections Office by March 5. Completed ballots may also be dropped off at City Clerk's Office City Hall, second floor, 14000 City Center Drive, or the James S. Thalman Branch Library, 14020 City Center Drive.
The library is directly across from City Hall.
Drop offs at the Chino Hills locations can be made during regular business hours or until 8 p.m. on election night.
Replacement Ballots will be available at the City Clerk's Office. Additional details about election matters can be found at www.chinohills.org/March2013Election.
The candidates are Debra Kay Hernandez, Ray Marquez, Rossana Mitchell and Jesse Singh.
Read up on the candidate biographies here.
Information: 909-364-2624.
Council members were told by their attorney that the Government Code indicates a vacant council seat cannot be filled by appointment if it would result in a majority of the council members having been appointed.
Council members Art Bennett and Gwenn Norton-Perry were appointed in August 2008 because no one else filed papers to run for a council seat.
The city will spend $135,000 from its General Fund for the election.
The cost for a regular election could cost up to $200,000.