text:
Pilot Assessment of Lopinavir/Ritonavir and Maraviroc (PALM)
This study has been terminated.
(unable to enroll expected number of subjects)
Rodwick, Barry M., M.D.
Information provided by (Responsible Party):
Barry M. Rodwick, M. D., Rodwick, Barry M., M.D.
ClinicalTrials.gov Identifier:
First received: September 19, 2009
Last updated: June 20, 2015
Last verified: June 2015
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Detailed Description:
This is a study to assess the response of lopinavir/ritonavir plus maraviroc (with no nucleoside medications) in HIV patients failing their initial antiviral therapy.
|HIV Infections Acquired Immunodeficiency Syndrome
|Drug: lopinavir/ritonavir plus maraviroc
|Phase 4
|Study Type:
|Study Design:
|Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
|Official Title:
|Pilot Assessment of Lopinavir/Ritonavir and Maraviroc in Experienced Patients
Resource links provided by NLM:
MedlinePlus related topics: HIV/AIDS
Drug Information available for: Ritonavir Lopinavir MaravirocU.S. FDA Resources
Further study details as provided by Barry M. Rodwick, M. D., Rodwick, Barry M., M.D.:
Primary Outcome Measures:
- Virologic response defined as viral load reduction of >/= 1 log [ Time Frame: 48 weeks ]
Secondary Outcome Measures:
- Assess proportion of patients with HIV-1 viral load < 48 copies [ Time Frame: 48 weks ]
- Assess time to loss of virologic response [ Time Frame: 48 weeks ]
- Assess development of resistance mutations in patients who develop rebound [ Time Frame: 48 weeks ]
- Compare serum lipid profile changes [ Time Frame: 48 weeks ]
- Assess safety and tolerability [ Time Frame: 48 weeks ]
- Assess degree of immune reconstitution [ Time Frame: 48 weeks ]
|Study Start Date:
|December 2009
|Study Completion Date:
|May 2015
|Primary Completion Date:
|May 2015 (Final data collection date for primary outcome measure)
|Assigned Interventions
lopinavir/ritonavir 400/100 mg bid plus maraviroc 150 mg bid
single arm
Drug: lopinavir/ritonavir plus maraviroc
lopinavir/ritonavir 400/100 mg bid plus maraviroc 150 mg bid
Other Names:
Detailed Description:
As long-term toxicity to many of the nucleoside medications have become known, interest has increased in treatment regimens that do not use these medications. This study is to assess the response of one such "nucleoside-sparing" therapy in patients who are showing failure to their initial nucleoside-containing treatment regimen.
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- HIV viral load > 1,000 on current antiviral medications
- No resistance to study medications
- Over 18 years of age
Exclusion Criteria:
- Hepatitis B co-infection
- Pregnancy
- Previous therapy with either of the study medications
- Ongoing substance abuse
- Significant history of other physical disease
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00981318
Please refer to this study by its ClinicalTrials.gov identifier: NCT00981318
|United States, Florida
|Barry M. Rodwick, M. D.
|Safety Harbor, Florida, United States, 34695
Sponsors and Collaborators
Rodwick, Barry M., M.D.
|Principal Investigator:
|Barry M. Rodwick, M. D.
|Barry M. Rodwick, M. D.
More Information
Keywords provided by Barry M. Rodwick, M. D., Rodwick, Barry M., M.D.:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on September 21, 2017
|Responsible Party:
|Barry M. Rodwick, M. D., Principal Investigator, Rodwick, Barry M., M.D.
|ClinicalTrials.gov Identifier:
|NCT00981318 History of Changes
|Other Study ID Numbers:
|Study First Received:
|September 19, 2009
|Last Updated:
|June 20, 2015
Keywords provided by Barry M. Rodwick, M. D., Rodwick, Barry M., M.D.:
Acquired Immunodeficiency Syndrome
treatment experienced
Additional relevant MeSH terms:
HIV Infections
Immunologic Deficiency Syndromes
Acquired Immunodeficiency Syndrome
Lentivirus Infections
Retroviridae Infections
RNA Virus Infections
Virus Diseases
Sexually Transmitted Diseases, Viral
Sexually Transmitted Diseases
Immune System Diseases
Slow Virus Diseases
HIV Protease Inhibitors
Protease Inhibitors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Anti-HIV Agents
Anti-Retroviral Agents
Antiviral Agents
Anti-Infective Agents
Cytochrome P-450 CYP3A Inhibitors
Cytochrome P-450 Enzyme Inhibitors
CCR5 Receptor Antagonists
ClinicalTrials.gov processed this record on September 21, 2017


text:
Library News :: List
Construction on Ground Floor Begins March 1
What does this mean? No access to the ground floor at all until at least mid-summer. If you like to study on the ground floor, you will need to find a new favorite spot. A table on the 2nd floor by the windows where it's quiet or a carrel on 1st?
What can we do to make the 1st and 2nd floors more appealing? Let us know:
- Email Pat at email@example.com
- Tell us when you come for tea Wednesdays 12:30-2:30
- Come to a strategy session Wednesday, February 13th at 4 pm.
We know this is a BAD time to limit study space in the library and we are sorry but the University needs the space for units moving out of the Hill University Center. We hope that as we make changes to the building, we can include changes that will be of direct benefit to students. Come tell us what those are!
Posted on February 6, 2013@ 12:48 PM by Peggy

subset: commoncrawl


text:
Question for the Money Doctors
Question submitted on Apr 15, 2010.
QuestionMy wife and I will both retire next year at 64. Her Social Security is about $12,000 and mine is about $24,000. We will also be drawing about $50,000 out of our IRAs and Roth IRAs. Will either of these be included in our MAGI for computing income tax?
The regular IRA will be included in MAGI. The Roth IRA is not included in MAGI. The MAGI calculation is used to determine how much of your Social Security income is taxable. AGI (not MAGI) is used for computing income tax.
For additional information visit http://www.360financialliteracy.org/


text:
The Penn State Greater Allegheny A Cappella Melody Lions will participate in the Music for the Spirit Festival, to be held at 7:30 p.m. on April 20, at the University of Pittsburgh's Petersen Events Center.
The Pittsburgh Symphony Orchestra will open the inaugural festival with "Singing City," a large-scale, historic concert event. Joining Music Director Manfred Honeck and the orchestra will be an ensemble of over 2,500 voices from the Pittsburgh region, including the Melody Lions. Doretta Whalen, adjunct instructor of music and director of the choir, will sing, along with students: soprano Yi Wen; altos Brittany Boucher, Courtney Handlovitch, Deziree Holyfield and Christina Moriarty; tenor Tim Tolbert; and basses Mike Mattis, and Kenneth Delgado Smith.
Repertoire highlights include the Chorale Finale of Mahler's Symphony No. 2 Resurrection, as well as the world premiere of a newly commissioned work for a cappella choir by Pittsburgh native, Jonny Priano.
For more information or to purchase tickets, visit Pittsburghsymphony.org/singingcity.


text:
Home Theater Makeover
Dave Bar worked for Crutchfield from 1981 until his retirement in 2016. After a 23-year stint in the sales department, he joined the home A/V writing staff. Dave's expertise and good humor will be sorely missed.
More from Dave Bar
Heads up!Welcome to this article from the Crutchfield archives. Have fun reading it, but be aware that the information may be outdated and links may be broken.
Putting together a great home theater system doesn't have to be hard. The key is pairing a good high-def picture with engaging surround sound. Along with adding new components, you might end up replacing some existing gear along the way. For instance, if you want to watch a high-def 3D movie on your new HDTV, you'll need to swap out that old DVD player for a 3D-ready Blu-ray model.
|Tami's old system
Tami's new space needs some new gear
Crutchfield Graphic Designer Tami recently finished the basement in her home. Knowing in advance that she wanted a home theater in her new space, she had her electrician run in-wall speaker wiring. But even though Tami's Sony 3D HDTV was ready to go, the rest of her A/V components simply weren't up to the task.
|Tami's new system
Room-filling sound without a room full of gear
"I wanted a system that was easy to set up, and that would blend in with the look of my newly finished basement," says Tami. "My old system had wires running all over the room, and it couldn't take advantage of my TV's 3D capability or high-resolution picture." No problem there. The in-wall wiring helped keep clutter to a minimum, and Tami's new 3D-ready Denon receiver features a handy first-time Setup Wizard. "I connected the receiver to my Sony TV and Blu-ray player with a couple of HDMI cables, then just followed the simple on-screen instructions." The Wizard also stepped her through the Audyssey® auto setup and room calibration adjustments for precise, enveloping sound. "The sound is amazing. It completely fills the room."
Tami begins her home theater installation
She started by preparing her new Polk Audio Blackstone TL2 satellite speakers for on-wall mounting using Pinpoint AM20 brackets.The Pinpoints fit directly on top of pre-installed in-wall junction boxes to create a clean, uncluttered appearance. She then mounted the TL2s on the Pinpoints and connected them to the in-wall wiring. The speakers sound great, and their white finish blends in nicely with her walls for a low-key look.
Netflix® movies plus broadcast high-def TV
|The Polk Blackstone center channel speaker hides neatly out of sight behind a grille cloth-covered drawer panel located directly under Tami's TV.
Another must-have for Tami was Netflix instant streaming for watching movies. "As a 'cable cutter' I don't really watch TV, but I am a big fan of Netflix for movies, so that had to be a part of my system." Tami's new Sony Blu-ray player not only delivers Netflix movies and more off the Internet, it also gives her a beautiful high-definition picture and stunning sound when spinning Blu-ray discs. And she can even watch 3D movies on her Sony flat-panel HDTV when she wants. Tami also made another discovery along the way:
"Because I don't subscribe to cable, one of my co-workers suggested trying an antenna to receive broadcast TV. So I connected one of our Channel Master antennas to an old satellite dish mount and now I get 11 digital channels, including all the networks in high-def. Oh my gosh, who knew getting local stations over an antenna was so simple?"
|Tami's new Denon receiver and Sony Blu-ray player nestle together comfortably, along with the rest of her gear, inside a BDI equipment cabinet.
Internet and wireless music options with AirPlay®
For music, the Denon receiver lets Tami surf thousands of Internet radio stations from around the world. Plus, it features Apple AirPlay — a technology that allows her to enjoy her iTunes® library from her networked computer. AirPlay can also work wirelessly. "My daughter, when she's home from college, will be able to listen to tunes from her iPod touch through the system without using any wires. It's a very cool feature." We couldn't agree more, Tami.
|Here's Tami enjoying her new home theater. When asked how she liked it, Tami said, "This new system totally rocks!"
Tami's new home theater components
Denon AVR-1912 home theater receiver
This receiver can drive five home theater speakers with ease, and still power a pair of outdoor speakers, too. Cutting-edge surround sound decoding turns your movie soundtracks into clear dialogue, high-impact explosions, and musical scores that immerse you in the unfolding story. Its Apple AirPlay® technology lets you stream music from your iTunes® library directly to the receiver, either from a networked computer or right from your iPhone®, iPad®, or iPod touch®.
Sony BDP-S580 Blu-ray player
If you aren't crazy about setting up new equipment, and like to skip right to the fun part, the BDP-S580 is the Blu-ray player for you. It comes out of the box ready to connect to your wireless home network, no additional wires or adapters required. It's all set to play exciting 3D movies on Blu-ray, movies off the Internet from Netflix®, YouTube™ videos, and even music stored on your home computer. And if you have a large collection of DVDs, the 'S580 not only plays them, it also upconverts their standard-def picture to near-HD quality.
Polk Audio Blackstone™ TL2 center channel speaker
Enjoy crisp movie dialogue and incredibly lifelike sound effects that really draw you into your on-screen entertainment.
Polk Audio Blackstone™ TL2
Compact yet powerful, Polk's TL2 satellite speakers deliver clear, detailed sound for your home theater and music-listening pleasure.
Polk Audio PSW111 powered sub
Add impact to your favorite movies and full-bodied bass to your favorite tunes with this powered sub.
Panamax M4300-PM Power line conditioner and surge protector
This surge protector/line conditioner delivers clean, safe power to help your home theater perform at its best.
Don't forget these useful accessories
Pinpoint AM20 Wall- and ceiling-mount speaker bracket
These décor-friendly speaker mounts attach directly onto an in-wall junction box.
Channel Master 3010 Outdoor HDTV and FM antenna
Pull in high-quality digital TV broadcasts, plus FM radio, with this antenna.
Niles HTP-7.1 wall plate
Use this Niles wall plate to give your in-wall wiring a clean, professional look.
AudioQuest Forest HDMI cables
Connect your A/V gear with these high-quality cables to enjoy cutting-edge picture and sound quality.
AudioQuest SUB-A subwoofer cable
Get clearer, more accurate bass from your powered subwoofer with this high-quality cable.


text:
As of Monday, 70,000 people unemployed six months or more lost all benefits
North Carolina's boast that it was "First in Flight" puts the state in the company of the innovators, those who helped move the nation forward. The latest "first" is nothing to brag about. The state has become the first in the nation to pull the safety net from under 70,000 unemployed workers.
By cutting weekly benefits and the length of time people may receive benefits, the state effectively also rejected federally funded extended benefits. This action is going to leave a lot of families in dire straits.
Contrary to what is apparently popular opinion among the majority's lawmakers in Raleigh, most hardworking Americans don't like to be unemployed. And even prior to action that slashed benefits by one-third, the weekly amount paid only a fraction of what the individual was making before.
As of Monday, 70,000 people unemployed six months or more lost all benefits; thousands more will lose benefits by the end of the year. Local social services departments and charitable organizations were gearing up for an influx of people seeking help. Unless some of those people had a fat savings plan to tap into, long-term unemployment already had taken a toll. Some had lost their homes, gone into bankruptcy or were hanging on by a thread. Now that thread has been cut.
The impetus for the cuts was the $2.8 billion the state owes the federal government because we had particularly high unemployment during the Great Recession, and because our state has taken longer than many others to emerge from that economic pit. Employers will pay a little more, too, but their burden will not be nearly as high as the one placed on the shoulders of the unemployed.
As some experts pointed out, the federal debt will be repaid only three years earlier than it otherwise would, and at a potentially higher human cost.
It may take a few weeks or longer to see whether these cruel cuts prove to be the panacea their sponsors envisioned, or another blow that sinks North Carolina closer to the bottom of its Southern neighbors in terms of economic progress.
The thinking among the sponsors, particularly the N.C. Chamber of Commerce, which wrote the law, is that slashing what were the highest benefits in the Southeast to more comparable with surrounding states will make North Carolina a mecca for new businesses and new jobs. By making the state more "business friendly," the logic goes, we'll make unemployment rarer.
That sounds great, if it proves true, but in the meantime anyone who is unlucky enough to lose a job because of the economy or because their employer's business goes under will have little cushion to help them stay afloat. "Any job is a good job" is a nice catch phrase, but a middle-class breadwinner with a mortgage to match would have grave difficulty digging out of that financial hole with a part-time, minimum-wage job with no health care benefits.
We should want more for our workers, and for our state.
Yes, there are some who game the system. But most are honest, diligent folks who fell victim to circumstances they could not control. Punishing them for the sins of the few is not only cruel, it is counterproductive.
Supporters of these new, leaner benefits say we'll be better for taking such drastic action. For all our sakes, let's hope they're right. Because if they are wrong, North Carolina will truly be in a race to the bottom.


text:
Audie Award Finalist, Erotica, 2014
For fans of Fifty Shades of Gray and Bared to You comes an erotic, emotionally charged romance between a powerful man who's never heard "no" and a fiery woman who says "yes" on her own terms.
He was the one man I couldn't avoid. And the one man I couldn't resist.
Damien Stark could have his way with any woman. He was sexy, confident, and commanding: Anything he wanted, he got. And what he wanted was me.
Our attraction was unmistakable, almost beyond control, but as much as I ached to be his, I feared the pressures of his demands. Submitting to Damien meant I had to bare the darkest truth about my past - and risk breaking us apart.
But Damien was haunted, too. And as our passion came to obsess us both, his secrets threatened to destroy him - and us - forever.
Release Me is an erotic romance intended for mature audiences.
©2013 J. Kenner (P)2013 Random House Audio
Say something about yourself!
"WILL cause sleep deprivation!!!!"
I have never heard of this series...I was doing a random search on Audible and it came up and OMG am I glad!!!!
Controlling dominant alpha male gazillionair...who is of course damaged. On the edge of loosing it alpha female...who is of course damaged....throw them together and watch the sparks fly, HOT sparks....SOOOOOOO HOT! So hot that I didn't want to go to sleep, I just wanted to keep listening!
Nothing specifically mentioned as far as dom/sub goes, but it's there just waiting to be discussed. The sex scenes were well developed and outstandingly described, IN GRAPHIC DETAIL.
It has a hot alpha male who is rich, but that is where the similarities to fifty shades stop. The female lead is NOT a virgin, THANK YOU J. Kenner for not following that cliche, there is no red room of pain, and they aren't from totally different worlds which was nice.
It had similarities to Bared to You with the rich alpha male again...but bared to you is more mid life to me, and this is late 20's early 30's of two damaged people finding someone else who is damaged enough to over look their damage and build a bridge.
I can get why people have compared this book to 50 and Bared, but it's a different animal to me....a very NICE animal!
I downloaded book two while only half way through book 1, and book three is due out in the summer so YEAH, not a really long wait....but I don't know how I will pass the time without another dose of the yummy Damian Stark.....oh so yummy!
Busy mom who loves to read but doesn't always have the time. I enjoy YA, Romance and the occasional Best Seller.
"Why isn't this book in your library????"
What a gem of a find! I don't read many books in a day (I'm a busy working mom) but I could not put this one down. It hooked me from the beginning and I just couldn't let it go.
As many other reviewers have said, if you enjoyed FSOG, Bared to You, Beautiful Bastard or If I Were You then you will enjoy this one too. It's the same formula but it doesn't feel like a rip-off. I'm not sure why this book isn't more popular but I'm glad I found this diamond in the rough.
I had no idea this was a trilogy but I'm looking forward to the 2nd and 3rd books!
4.5 stars for a Very Hot Listen!
I love audio books that the characters come to life and have me feeling as if I was there too.
"3 stars but..."
The story line was good but the narrator was so breathy OMG... SW needs some narration lesson NO LIE! I found it hard to listen to her but made it through. The story was good and if you can make it through too then enjoy and get the rest of the series. Worth a credit sure why not. LOL Happy Listening!
"A cross of 50 Shades series & Bared to you series"
Yes, Narrator was good and it's good novel.
Fifty Shades of Grey and Bared to You. These books are very similar. If you enjoy these 2 book series, you won't be disappoint with one. I think Damien is a blend of Christian Grey and Gideon Cross. He's pretty awesome.
Damien and Jamie.
Yes, I listened to this book in one sitting. It was a long one.
I did not realized that this is a series. I am glad it is. The 2nd book & 3rd book scheduled for this year. I can't wait.
Damien's trouble past tucked my heart. I am concern with Nikki's problem. I wonder how the author is going to deal her issue moving forward in the series.
I have 3 kids that occupy all the TV's in the house...enough said...addicted to audiobook ....shhhh don't tell my husband ;-)
"Going against the grain here..."
I actually didn't like it. Not only is the story line way too close to Fifty Shades of Grey and Crossfire but the main character Nikki Fairchild flat out annoyed me. I couldn't relate to her and there for couldn't really get into liking the book. Lately it seems that all young billionaires are controlling sexual deviants that all have a knack for aviation and like to keep dossier on their females of interest, and some type of ex-girl friend is messing up their lives now. But in Release Me Nikki Fairchild is the one that is 50 shades of messed up and has attracted the interest of Billionaire Damien Stark. Nikki is a blonde hair, green eyed ex- child pageant contestant that ends up being super smart with a double major in computer science, she writes apps and is apparently MIT material. Nikki emotionally on the other hand, I don't know how to put this, but she would be on the short bus! She has deep seated mommy issues that turn her into a cutter as a teenager and about 4 or 5 times in the book she completely flies off the handle yelling at Stark and even slapping him before she gathers all the information on the situation. Once the information is out it appears that she constantly over reacting due to always jumping conclusions. I just personally can not stand that trait in a person, to me Nikki just seems to be bipolar, emotionally unstable. I probably won't finish the series.
If the story appears to you then I would go ahead and give it a try but it just wasn't my cup of tea.
"Great... I loved it!"
I love listening to books where the narrators voice is not annoying... This book is steamy and has a plot with mystery and suspense... and of course some erotic romance.
The ending was a cliffhanger and I am disappointed that I have to wait until July to hear more.
Damian...I hope that is how you should spell his name. He is a mystery and I can't wait to figure him out in the remaining books
Yes, it kept me up all night, I couldn't turn off my brain and I wanted to know more.
I like books with raw primal hunger... Listening to books like 50 Shades of Grey, Bared to You, Reflected in You, etc invokes a curiousity in me to step outside my comfort zone... Try a new wine, a new restaurant, a different spa service-- Enjoy life more freely!
"I was not impressed"
I did not enjoy this book at all i just felt that it was a spinoff of all the other books that I have read. the narration was just ok.
"This story was forgettable"
Okay I just don't see what the buzz about this book is all about, it's not even close to the league of FSOG and the Crossfire series. Book is well written but the story is mediocre, I didn't find the sex scenes all that hot. I think you can skip this one, I can't remember the main characters names that's how forgettable this book was.
When I clean, drive or exercise I listen to romance. The steamier the better but it must have a great story as well!
"Above my expectations!"
I resisted this book thinking that it would be so similar to "Fifty Shades of Grey" that it wouldn't hold my interest. I does flow in a similar fashion but it is a unique and interesting storyline. I was surprised to find, I liked it! It is a simple story, no real depth but what is referred to as a beach read. Difficult emotional subjects such as "cutting" and suggestions of abuse are mentioned but neither are done distastefully but instead in understandable ways. I recommend this book to those that like the fanfiction style books from the "Twilight" series. I'm not sure if that is what it is but if it is Twilight inspired it is one of the better runoff books available. Enjoy!
I've always been a avid reader so now I'm a avid listener. I prefer the paranormal genre but I do like to switch things up. It's boring if you don't have variety. Of course I do love the romance and the hotter the better. Also, you can't beat a good thriller filled with suspense and a ending you can't even guess at until the very end.
"Oh it's good!!"
It's a very sexy listen. It reminds me of 50 Shades. In saying that, I like 50 better. In listening to this book it seems like maybe another book is coming from these two characters (like the 50 series). It's a good listen. It's interesting, but not fabulous. I'd buy it on sale and save my credit.
Report Inappropriate Content
If you find this review inappropriate and think it should be removed from our site, let us know. This report will be reviewed by Audible and we will take appropriate action.


text:
What did we do before Netflix? Go out and rent videos from Blockbuster or Hollywood Video (RIP)? You actually had to leave the house to go find the media that would keep you glued to your couch. But thankfully, now we have Netflix, the addictive online service inherently designed to make the video rental process ten times quicker and easier than before. Even though, you could get DVDs mailed (lol) still, it's all about the "Watch Instantly" option. Why should you have to wait for the mailman and have to leave your couch? Just "Watch Instant" your next binge watch.
That's why it's often so annoying to sift through the Watch Instantly library and learn that the one flick you've been dying see is only available via hard-copy disc. Such constant disappointment (Where is Notting Hill?) has led many to criticize the website's streaming service as a "slim pickings" letdown, but, truth be told, that reputation isn't fair. Having combed through the site's entire Watch Instantly catalog, we've made wait-less gratification infinitely easier with this list of the 100 Best Movies Streaming on Netflix Right Now. Now go forth, fellow Netflix Bingers, and get ready to never leave your couch cold again. And once you've binge-watched this whole list, check out the best comedy movies, the best romantic movies, and the best TV shows streaming on Netflix right now.


text:
Study to Find Optimal Dose of Local Spinal Anesthetic (Mepivacaine) Combined With Narcotic (Fentanyl) For Knee Surgery
This study has been completed.
Hospital for Special Surgery, New York
Information provided by (Responsible Party):
Hospital for Special Surgery, New York
ClinicalTrials.gov Identifier:
First received: January 4, 2012
Last updated: March 9, 2016
Last verified: March 2016
- Full Text View
- Tabular View
- Study Results
- Disclaimer
- How to Read a Study Record
Prolonged motor block and delayed ability to walk are limitations of spinal anesthesia in ambulatory (same-day) surgery. This can be improved by lowering the dose of local anesthetic (a medication that, when injected around nerves, blocks nerve conduction, resulting in numbness and weakness) used in the spine, but too low a dose can result in an incomplete block (inadequate anesthesia) in some patients. There is evidence that adding a low dose of fentanyl, a narcotic, to mepivacaine enhances the anesthetic effect. The purpose of this study is to determine the lowest dose of mepivacaine, a local anesthetic, when combined with fentanyl, for which spinal anesthesia is adequate for ambulatory knee arthroscopy.
|Arthroscopic Knee Surgery
|Procedure: Mepivacaine (24 mg) plus fentanyl Procedure: Mepivacaine (27 mg) plus fentanyl Procedure: Mepivacaine (30 mg) plus fentanyl Procedure: Mepivacaine
|Study Type:
|Study Design:
|Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Participant, Investigator)
Primary Purpose: Treatment
|Official Title:
|Optimal Dose of Spinal Mepivacaine Combined With Fentanyl For Knee Arthroscopy
Resource links provided by NLM:
MedlinePlus related topics: Anesthesia Opioid Abuse and Addiction
Drug Information available for: Mepivacaine Fentanyl Fentanyl citrate Mepivacaine hydrochlorideU.S. FDA Resources
Further study details as provided by Hospital for Special Surgery, New York:
Primary Outcome Measures:
- Time From Spinal Administration to Block Regression to the S1 Dermatome in Post-Anesthesia Care Unit (PACU) [ Time Frame: Participants will be followed for the duration of their recovery after surgery in the post-anesthesia care unit (PACU), an expected average of 2-4 hours. ]The time frame of the study for each patient only covers the period between time of surgery and time of discharge from the hospital, which is on the same day as the day of surgery
|Study Start Date:
|December 2011
|Study Completion Date:
|December 2013
|Primary Completion Date:
|July 2012 (Final data collection date for primary outcome measure)
|Assigned Interventions
|Active Comparator: Mepivacaine 37.5 mg
Procedure: Mepivacaine
Mepivacaine 37.5 mg
|Active Comparator: Mepivacaine 30 mg plus fentanyl 10 µg
Procedure: Mepivacaine (30 mg) plus fentanyl
Mepivacaine (30 mg) and fentanyl (10 µg)
|Active Comparator: Mepivacaine 27 mg plus fentanyl 10 µg
Procedure: Mepivacaine (27 mg) plus fentanyl
Mepivacaine (27 mg) and fentanyl (10 µg)
|Active Comparator: Mepivacaine 24 mg plus fentanyl 10 µg
Procedure: Mepivacaine (24 mg) plus fentanyl
Mepivacaine (24 mg) and fentanyl (10 µg)
|Ages Eligible for Study:
|18 Years to 60 Years (Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Subjects aged 18-60
- Patients scheduled for "simple" knee arthroscopies, including meniscectomy, debridement, and plica.
Exclusion Criteria:
- Subjects aged <18 or >60
- Subjects greater than 190 cm in height
- Patients scheduled for ligament reconstruction or surgery involving bone
- Daily use of narcotics for greater than one week pre-op
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01701102
Please refer to this study by its ClinicalTrials.gov identifier: NCT01701102
|United States, New York
|Hospital for Special Surgery
|New York, New York, United States, 10021
Sponsors and Collaborators
Hospital for Special Surgery, New York
More Information
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on September 21, 2017
|Responsible Party:
|Hospital for Special Surgery, New York
|ClinicalTrials.gov Identifier:
|NCT01701102 History of Changes
|Other Study ID Numbers:
|Study First Received:
|January 4, 2012
|Results First Received:
|February 11, 2016
|Last Updated:
|March 9, 2016
Additional relevant MeSH terms:
Analgesics, Opioid
Central Nervous System Depressants
Physiological Effects of Drugs
Sensory System Agents
Peripheral Nervous System Agents
Adjuvants, Anesthesia
Anesthetics, Intravenous
Anesthetics, General
Anesthetics, Local
ClinicalTrials.gov processed this record on September 21, 2017


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"Trap Talk" is now available on iTunes! Remember, any song you buy on iTunes from the upcoming album, "The Appeal", will be discounted from the cost of the complete album on SeptemBURRR 28th! Click Below
You can also get the special album pre-order and receive a digital download of the album the day before it drops!


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Meet the Paradise in the Caribbean coast of Costa Rica
On the Costa Rican Caribbean horizon, you can find a number of natural wonders, from the majestic sunrise to that wonderful event of the turtle nesting on its beautiful beaches.
The wide variety of smells, tastes and colors of our Caribbean cost is mesmerizing, and all the visitors who come for the first time fall deeply in love with it.
A flock of wild animals will be your company during you visit to the Caribbean:
All persons visiting the Caribbean cost of in our country can be assured they will always have a pleasant company. Hanging of the branches of the trees, there is a great diversity of monkeys cheering up your day; then, you will hear birds whistling when they head to the beach at the tops of the trees. Finally, lots of turtles emerging from the sand will teach you the wonderful gift of life.
The best traditional food is available in the Costa Rican Caribbean cost:
You are going to fall in love with the Caribbean cook of our majestic cost, since the dishes, ingredients and flavors come from a long African heritage. And there is no hint of doubt, you won´t leave leave our Caribbean without tasting our delicious Rice & Beans or our "Patí" accompanied by a mouth watering "frog water" (a drink made with lemon juice and molasses).
Without any doubt, the great wonders of Costa Rica's Caribbean will leave memories you would love to repeat again and again
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WYANDOTTE (AP) -- Power plants in several Michigan cities are burning millions of tires each year to make electricity, prompting some pollution concerns as state officials and plant operators defend the practice.
According to plant operators, tire-derived power is cheaper and cleaner than burning coal or wood, the Detroit Free Press reported. They say that they are keeping tires out of landfills and helping the state clean up dump sites.
Wyandotte's municipal power plant creates electricity for about 10,000 households and 3,000 businesses. Two boilers run off natural gas and the third uses tire shreds and coal. According to officials, tires contain more energy than coal, pound-for-pound.
"We burn about 300 tons of fuel per day in this boiler. It generates less waste, lower emissions and more-efficient combustion," said James French, the former director of the city's power supply.
Some who live near the eight plants that burn tires to make power in Michigan, however, have challenged them because of pollution concerns.
In Hillman, a village in Alpena and Montmorency counties, the elementary school is next to the power plant. In 2002, when plant officials applied to increase their use of tires, people like Donna Baranyai, with two children at the school, asked that the application be rejected.
"It still concerns me," said Baranyai, who eventually moved her children to a school in a neighboring community. "There's a community park at the end of the street. There are times when you go there and the playground equipment will be all covered in black."
Michigan officials say 1991 legislation that gave them the power to regulate and remediate used tires has fueled an economy centered on tire reuse and recycling. Shredded bits of tire are mixed with coal and wood to be burned to create electricity, and it's is the single largest use of old tires in Michigan.
"We have all these piles of tires and they are looking for any use they can get because you can only do so much with tires," said Neil Taratuta, supervisor of the tire- and wood-burning Viking Energy plant in Lincoln, a village in Alcona County, about the state's scrap tire programs.
Michigan Department of Environmental Quality data suggest that over 20 years, about 31 million discarded tires have been reduced to 2 million and more than 200 known illegal tire dump sites have been reduced to 55.
"Most things are going to be cleaner when compared to coal in terms of pollutants," said Steve Weis, environmental engineer for MDEQ in Detroit.


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BAY81-8781, I.V. Aspirin in the Indication of Acute Coronary Syndrome (ACS) (ACUTE)
This study has been completed.
Information provided by (Responsible Party):
ClinicalTrials.gov Identifier:
First received: May 28, 2009
Last updated: June 24, 2015
Last verified: June 2015
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
No Study Results Posted on ClinicalTrials.gov for this Study
|Study Status:
|This study has been completed.
|Study Completion Date:
|July 2014
|Primary Completion Date:
|April 2014 (Final data collection date for primary outcome measure)


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Editor's Note: TheStreet ratings do not represent the views of TheStreet's staff or its contributors. Ratings are established by computer based on metrics for performance (which includes growth, stock performance, efficiency and valuation) and risk (volatility and solvency). Companies with poor cash flow or high debt levels tend to earn lower ratings in our model All three major indices are trading up today with the Dow Jones Industrial Average ( ^DJI) trading up 50 points (0.4%) at 14,380 as of Friday, March 8, 2013, 11:50 AM ET. The NYSE advances/declines ratio sits at 1,811 issues advancing vs. 1,063 declining with 140 unchanged. The Consumer Non-Durables industry currently sits up 0.5% versus the S&P 500, which is up 0.2%. Top gainers within the industry include Carlisle Companies ( CSL), up 1.6%, and International Paper ( IP), up 0.9%. A company within the industry that fell today was Nike ( NKE), up 1.1%. TheStreet Ratings group would like to highlight 5 stocks pushing the industry higher today: 5. Crown Holdings ( CCK) is one of the companies pushing the Consumer Non-Durables industry higher today. As of noon trading, Crown Holdings is up $0.60 (1.5%) to $39.45 on average volume Thus far, 280,166 shares of Crown Holdings exchanged hands as compared to its average daily volume of 736,700 shares. The stock has ranged in price between $39.04-$39.46 after having opened the day at $39.14 as compared to the previous trading day's close of $38.85. Crown Holdings, Inc. engages in the design, manufacture, and sale of packaging products for consumer marketing companies worldwide. Crown Holdings has a market cap of $5.6 billion and is part of the consumer goods sector. The company has a P/E ratio of 10.4, below the S&P 500 P/E ratio of 17.7. Shares are up 5.5% year to date as of the close of trading on Thursday. Currently there are 6 analysts that rate Crown Holdings a buy, no analysts rate it a sell, and 3 rate it a hold. TheStreet Ratings rates Crown Holdings as a hold. The company's strengths can be seen in multiple areas, such as its good cash flow from operations, increase in stock price during the past year and impressive record of earnings per share growth. However, as a counter to these strengths, we find that the company's profit margins have been poor overall. Get the full Crown Holdings Ratings Report now. It's Official: Action Alerts PLUS beats the S&P 500 with Dividends Reinvested! Cramer and Link were up 16.72% in 2012. Were you? See what they are trading for 14-days FREE
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The new Italian Champion Barista 2017 is Francesco Masciullo.
The twenty-five year-old took the spotlight in Rimini by presenting a competition concept focused on global warming, a phenomenon that is enormously influencing the world of coffee. In this case, it offers a positive effect, since the higher temperatures give coffee beans entirely new and unprecedented aromas.
The new Italian Champion Barista 2017 is Francesco Masciullo. The twenty-five year-old took the spotlight in Rimini by presenting a competition concept focused on global warming, a phenomenon that is enormously influencing the world of coffee. In this case, it offers a positive effect, since the higher temperatures give coffee beans entirely new and unprecedented aromas.
"My team and I have selected three types of beans," said Masciullo in a recent interview, "which owe their exceptional features as regards taste precisely to global warming. Each of the three beans formed the basis of one of the drinks that I submitted to the jury."
These are the details, care and unique attention that make the difference, and testify to the extended research and passion that led the young barista to win the title of Champion.
He will represent Italy at the World Barista Championship in Seoul, Korea, from 9-12 November.
IGEHO 2017 in Basel – from 18 to 22 November 2017
IGEHO is widely acclaimed as the most important international trade fair for the hospitality, food and catering industries, and the nursing home services in Switzerland. It is here that trade professionals gather to seek new input and let themselves be amazed and seduced. A place to celebrate and experience hospitality.
The Coffee House of Rancilio Group is waiting for you at HOST 2017
"Feeling at home". A special home. The quality coffee house brewed by our professional equipment, both of traditional and fully-automatic. Around this important topic we have developed our exhibition space rich of thematic and demo corners. An area projected to welcome our visitors and make them feel as an integral part of our presence at HOST Milan.
The second edition of "Umami Train the Trainers Camp" with the participation of Rancilio Group
The second edition of "Umami Train the Trainers Camp" has just drawn to a close. This is an outstanding event in the ambit of international training activities on coffee-related topics, through which Umami Area updates authorized trainers of the Specialty Coffee Association.
Opening of Rancilio Group Deutschland in Frankfurt
Rancilio Group Deutschland: from Weikersheim to Frankfurt for a wider-reaching, more incisive presence
Founded in 2002 in Weikersheim as the Germany-based subsidiary of the Swiss brand Egro, Rancilio Group Deutschland has also been handling sales of the Rancilio range in both Germany and Austria ever since 2008. Thanks to its network of expert specialist dealers, the company is able to dispatch finished products and spare parts from its in-house warehouse promptly and with unrivalled efficiency.
All set for the ANTONIETTO RANCILIO TROPHY 2017
Just a few hours to go before the start of the 2017 edition of the historical cycling race held in commemoration of Antonietto Rancilio, the entrepreneur who passed away in 1983 and, with his eponymous company and the support of brothers Nino and Romano, exported the espresso coffee culture worldwide.
A new partnership in the name of espresso coffee
Rancilio Group has recently joined the Fórum Cultural del Café, an association founded in 1997 with the aim of encouraging closer contacts among the protagonists of the supply chain to promote coffee culture on the Spanish market.
Milan, food capital with Classe 11
The Milano Food City event will run from 4 to 11 May. A week packed with events, meetings and cooking shows in which the Rancilio Group will be taking an active part, in collaboration with Altogo, within the "Coffee and spices cluster" at Palazzo Bovara in the city centre.
The Classe 11 is the official machine of the Spanish Coffee in Good Spirits Championships
From 11 to 14 May, the Spanish region of Galicia will come to life with tasting sessions, contests and workshops dedicated to the multifaceted world of coffee, as part of the fourth edition of the Spain Coffee Festival event. This trade fair has been specifically conceived to valorise the artisanal nature of espresso coffee and the most delicious variations on this theme.
The Rancilio Extraction LAB lands in Seattle for SCAA 2017
During the trade fair organized by the Specialty Coffee Association of America, better known as SCAA, scheduled to run from 21 to 23 April 2017 at the Washington State Convention Center in Seattle, Rancilio Group has displayed Xcelsius technology for the Temperature Profiling of coffee in an elegant and refined booth, purpose built to house the Extraction LAB format launched in March at the most important European Coffee Festival which was held in London.
The Extraction LAB of Rancilio at the London Coffee Festival 2017
All espresso drinks, whether they be a short black, a macchiato, a flat white, a cappuccino, a café creme are built on the quality of the coffee extraction.
Rancilio Group and Microsoft: new innovative synergies
During the inauguration of the Microsoft Italia headquarters in Milan, an authentic high-tech showcase of excellence, the US colossus gave a first-ever preview of the implementation of Cortana software on the fully automatic Egro ONE machine.
Classe 11 at the 2017 edition of the Trismoka Challenge
For the seventh year running, Rancilio Group is to be the official sponsor of the Brescia-based competition open to coffee artists, who will be challenging each other in the preparation of the flavour-packed beverage, delicious cappuccinos and delectable coffee-based beverages of their own invention with the aid of our professional Rancilio Classe 11 machine.
In Hamburg for Internorga 2017
The 2017 edition of Germany's leading international trade fair in the food and beverage sector will be held from 17 to 21 March at the Hamburg exhibition centre. Just as we do every year, Rancilio Group will take part in the event through our German subsidiary Rancilio Group Deutschland.
Countdown for Sigep Rimini 2017
From 21 to 25 January 2017, the Rancilio Group will be present at the Sigep Rimini fair with all of its product technology.
Rancilio Group for a green, sustainable and responsible 2017
Can trees save lives? It seems like a vision from a sci-fi movie, but that isn't the case. From a report published by Nature Conservancy, the leading international organisation for safeguarding and conserving the environment, entitled Planting Healthier Air we learn that the only way of lowering pollution worldwide is to plant trees, as many as possible.
Classe 11 reconfirms itself as the official machine of the Italian Barista Championship finals
It is with great pleasure that we share that Rancilio's Classe 11 has once again been chosen by SCAE Italia as official sponsor of the 2017 and 2018 editions of the Italian Barista Championship.
Al vincitore dei Barawards 2016 una Silvia Linea Casa
Lo scorso 12 dicembre, al Museo Nazionale della Scienza e della Tecnologia Leonardo Da Vinci a Milano c'erano oltre 300 persone, provenienti da tutta Italia, per celebrare con le riviste di settore Bargiornale, Ristoranti e Webar i Barawards 2016, premi alle eccellenze dell'ospitalità made in Italy.
Rancilio Group and Tuttobar Service at GOURMET
The second edition of Gourmet will take place from 13 to 15 November 2016 at Lingotto Fiere in Turin!
Egro Suisse at IFAS 2016
We will be at IFAS trade fair for the healthcare industry for the second time in Zurich to present our full range of machines for making quality hot beverages.
In Lucerne for ZAGG 2016
The new fully automatic Egro BYO is the answer to the growing demand for large, easy to use displays, and offers a revolutionary new feature: the user can now interact with the machine directly from a tablet.
Rancilio Group with Aleph Trade at PIR in Moscow
From 17 to 20 October we will fly to our partner Aleph Trade in Russia for the 2016 edition of Moscow Coffee & Tea Expo inside the trade fair PIR.
Rancilio Group has joined the national Pink Ribbon campaign for breast cancer prevention, promoted by Lilt - the Italian League for the Fight Against Cancer. Its aim is to raise awareness on the vital importance of prevention and the early detection of breast cancer.
At the New York Coffee Festival with the Temperature Profiling
From 16 to 18 September, the Xcelsius technology for espresso Temperature Profiling will arrive in the Big Apple for the 2016 edition of the New York Coffee Festival.
Rancilio Group celebrates the 80th anniversary of the Fiera del Levante
The fair in Bari marks a major milestone in 2016. In collaboration with our partner, the Lavermicocca Corporation, the Rancilio Group will celebrate the 80th anniversary of one of the most prestigious Italian exhibitions from 10 to 18 September.
First Malaysia Coffee Tour with Classe 11 Xcelsius
Penang - July, 19, Kuala Lumpur - July 20 and Johor Bharu - July, 21 are three dates to note in the calendar. Classe 11 espresso machine and Xcelsius Temperature Profiling technology will take part in the First Malaysia Coffee Tour organized by our local distributor Global Coffee Resources.
Rancilio will be in Dublin for World of Coffee 2016
This year the international protagonists of excellent coffee will gather in Dublin from 23 to 25 June. Ireland, the cultural and economic homeland of craft beer, will thus have an opportunity to present itself to the world in its new role as an important player on the quality espresso scene.
Microsoft acquires Solair, the company that has integrated Internet of Things in the Rancilio Group's product range
The United States colossus, Microsoft, has acquired the Italian company Solair, specialized in IoT (Internet of Things) technology, and which has also introduced IoT to all of the professional coffee machines in the Rancilio and Egro ranges.
Our third Sustainability Report
We are pleased to present you with this year's edition of BEATS: a document that perfectly reflects the confident and transparent relationship we have built up with our stakeholders down through the years, day after day, in a shared experience of reciprocal growth.
CONNECT awarded at Smau Padova
The IoT application made by the Rancilio Group in collaboration with Solair, a software house founded in 2011 and focused on the Internet of Things, was awarded at Smau Padova on Thursday, 10 March.
McDonald's Corporation Worldwide Conference 2016
From 11 to 14 April, we shall be in Orlando Florida to take part in the McDonald's Corporation Worldwide Conference for the second year running, as official supplier of the international fast food giant.
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Broward Sheriff's Office robbery detectives are searching for a robber who took the proper steps to make sure his fingerprints weren't left at the scene of the crime by putting on a glove on his left hand, and then used his right hand to commit the crime.
The well-thought-out plan was put into motion November 29 at the Walgreens at 3099 N. SR 7 in Lauderdale Lakes. Around 10:45 p.m., surveillance cameras are rolling as the suspect walks into the business and stands in line. As he patiently waits, he removes a glove and puts it on his left hand and is seen slipping merchandise into his pockets.
Once it's his turn and the cashier rings up his item, he hands the employee the money, but when the register swings open he reaches in with his right hand and takes the cash and runs out.
The suspect is a black male, about 6' tall, 185 lbs. and is seen wearing a black baseball cap with purple lettering, a black and purple, hooded sweatshirt and gray pants.
Anyone with information about this robbery or the identity of the suspect is asked to contact BSO Robbery Detective Theo Woulard at 954-321-4553 or Broward Crime Stoppers at 954-493-TIPS (8477) or www.browardcrimestoppers.org. A reward of up to $1,000 is available for information leading to an arrest.
***Media Note: A good-quality video of the robbery is available on our website www.sheriff.org. The video shows two camera angles.
Posted At: 01/14/2013 02:17 PM
- PIO 13-1-10 - Wrong Hand Robber
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Giants hoping for spark as Scutaro comes off DL
SAN FRANCISCO -- After weeks of anticipation, The Return occurred at AT&T Park on Thursday afternoon.
OK, so Marco Scutaro returning to the Giants isn't quite as monumental as LeBron James' decision to return to Cleveland, but the veteran is a very welcome addition to the struggling club.
With an afternoon game Saturday, Scutaro was held out of the starting lineup Friday night, but manager Bruce Bochy said Scutaro would make his first start of the season Saturday. How often Scutaro plays will depend on how his back holds up, but the Giants' hope is that his presence alone can provide a boost for the team.
"His experience and that veteran leadership he provides, that's invaluable," Bochy said of Scutaro, whom he referred to as a "core player." "It's good to have him back. He's very popular in that clubhouse, so hopefully he's going to be a shot in the arm for us."
That is, if his back holds up.
"My back is better, but it's not the way it used to be," Scutaro said. "The pain is still there. Sometimes I have a good day, sometimes I have a bad day. I'm just going to try and go day by day."
Scutaro said rotation from swinging the bat causes aggravation in his back with each swing, making the back tougher to cope with in the batter's box than in the field. Though the problem is an issue he has to contend with all the time, on or off the field.
"You're sitting, it hurts. Standing up, it hurts. Laying down, it hurts. It's not just your stroke, but your whole life," Scutaro said. "Tie your shoe, it hurts. Every step you make, it hurts. It just [stinks], pretty much."
Bochy said the 38-year-old won't play both games when an afternoon game follows a night game, but aside from that, how the platoon at second base with Joe Panik and Scutaro will play out remains to be decided.
Ryan Hood is an associate reporter for MLB.com. Follow him on Twitter @ryanhood19. This story was not subject to the approval of Major League Baseball or its clubs.


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Avery Templates and Mac®—A perfect combination!
Want to design and print the perfect item right from your Mac? Look no further. With Avery Design & Print Online, you're covered. Featuring thousands of customizable predesigned and blank templates for your unique personalization.
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Vision: To lay the foundation for a no-kill nation.
The St. Tammany Humane Society has been serving St. Tammany parish as the only non-profit, non-governmental animal sheltering and welfare organization for more than 55 years. Our doors opened to the community neglected, abandoned and abused pets in 1953 by Holly Frederick Reynolds in memory of her cocker spaniel, Yankee Doodle Dandy, because she truly wanted to make a difference in the lives of these orphaned companions. Today, the mission is the same, but we have several new programs and services in place to do just this-to give these animals a new leash on life; we just need the support of our community to continue the mission and realize our vision.
We truly would not be here without you!
Thank You!
Your message has been sent to St. Tammany Humane Society.
You'll receive a copy, too, at to help you keep track of which pets you've inquired about, and which shelters and rescues you've emailed.
NOTE: Some shelters have physical locations you can visit; some of these shelters may only have pets for a limited time, so please do not wait for a reply—just go visit the shelter! Other organizations are rescue groups run by busy volunteers who may take a while to reply. You can find information about the shelter or rescue group caring for this pet, and their adoption procedures, on the pet's details page on Adopt-a-Pet.com.


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Seed Tape, Set of 4
This item is currently not available.
Additional Information
Exclusive | Seed Tapes: Precision Planting with No Waste, No Thinning
Seed Tapes are the perfect, no-waste way to plant where space really counts — in containers, raised beds, or small gardens. Each strip of biodegradable paper is embedded with perfectly spaced seeds; simply unroll into a planting furrow and cover. Planting is precise, there's little or no thinning needed, and the germination rate is outstanding. Seed Tapes are made by Suttons Seeds, one of England's most trusted growers, and we're offering some of their most reliable and rewarding vegetable varieties.
2009 was a tough year for gardeners in the Northeast: cold, windy, plagued by heavy rains and blight — not the best year to try a new product like these Seed Tapes in our test gardens. But, to our surprise, nearly 100 percent of the seeds germinated. Popular with English gardeners for years, Seed Tapes have made believers of us. This set of 4 Seed Tape includes three tapes each of Carrot (Amsterdam Forcing 3), Radish (French Breakfast), Lettuce (Webb's Wonderful) and Beet (Boltardy).
- Save when you buy this set of 4 seed varieties
- Seed tapes are a terrific way to plant small gardens and raised beds
- Also ideal for mid-season succession planting between rows
- Seeds are evenly spaced and embedded in biodegradable paper tape
Product Details
- Biodegradable paper with embedded seeds
- Four seed types with 16-1/2' total length each
- Non-GMO seed
- Gardener's Supply Exclusive
REVIEW SNAPSHOT®by PowerReviews
- Easy to use (3)
- Lightweight (3)
Best Uses
- Garden (3)
- Reviewer Profile:
- Midrange shopper (3)
Reviewed by 5 customers
- Flimsy
Best Uses
- Garden
Comments about Seed Tape, Set of 4:
These seed tapes aren't bad, but they're also not a piece of cake to use. They're packaged in an almost toilet-paper-like covering, which is a little fiddly to separate from the roll.
Still, for small seeds, I think there is less waste involved when using this tape than not. I wish there were more varieties available to choose from.
- Primary use:
- Personal
Comments about Seed Tape, Set of 4:
was very disapointed in the seed tapes i purchased 2 different kinds only 1 out of 20 seed actualy grew very bummed out over it had to replant twice
- Primary use:
- Personal
- Easy To Store
- Easy To Use
- Lightweight
- Very easy to work with
Best Uses
- Deck
- Used empty flower boxes
Comments about Seed Tape, Set of 4:
I used two empty flower boxes oon our deck to plant carrots radishes and lettuce.
- Easy To Use
- Lightweight
- Limited varity of plants
Best Uses
- Garden
Comments about Seed Tape, Set of 4:
easy to use
already seeing spaced seedlings.
nice to have a product that preforms as advertised
- Durable
- Easy To Store
- Easy To Use
- Lightweight
Best Uses
- Garden
Comments about Seed Tape, Set of 4:
Small seeds such as radishes, carrots and beets are so much easier to plant using the seed tape--no more 10 seeds in one place and none in another.When will lettuce seeds come this way????
- Ships FREE! This item will be excluded from the calculation for standard shipping on your order. If you have other products in your cart, only the shipping charges for those items will be applied.


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There's Another Name for Regime ChangeNews at Home
All indications are that regime change in Iraq is still on the agenda of the Bush administration. Ironically, the administration has created a situation in which anything less than the invasion, defeat and occupation of Iraq will be considered a failure.
Why have President Bush and his advisers staked their reputation on such a risky policy as regime change? An examination of the Cold War policy of"rollback" may help explain this obsession.
"Rollback," a concept articulated in a seminal Cold War document produced by the National Security Council in 1950, declared the importance of pushing the Soviet Union back from those territories conquered in the last months of World War II. Containment would not suffice.
The Cold War document contains fascinating parallels with our present situation. Most striking is the apocalyptic picture of a powerful America facing disaster in just a few short years if it does not take immediate steps to extend its military capabilities. There is the same whiff of hysteria about prospects for the future that one finds in current administration pronouncements about the need to eliminate Iraq before it gains a capacity to use weapons of mass destruction against the United States.
The worries voiced in 1950 at least reflected the documented loss of the American postwar atomic monopoly with the test of the first Soviet atomic weapon in 1949. The combination of the Soviet Union's atomic weapons and its superiority in conventional forces placed the United States at a severe disadvantage that some feared would only get worse.
The position the United States now occupies in the world is unparalleled in modern history. Almost every other country in the world is more or less on the level of Panama compared with the military strength of the United States. This extraordinary situation may explain why the president believes he can bring about regime change in Iraq with only a little more trouble that his father, George H. W. Bush, faced in bringing about regime change in Panama thirteen years ago.
One major problem, however, is the vast difference between possibilities in the Middle East and the American experience in Central America and the Caribbean, where we have largely done as we pleased, numerous regime changes included. It isn't that regime change in the Western Hemisphere didn't have uniformly disastrous results, only that the United States never had to pay the price of those results.
If there are lessons to be learned from the Cold War, it may be that the blunt application of force is rarely the answer. The idea of containment was that force was available to use in the last resort. Rollback aimed at more, and it became a far cruder instrument of policy.
The same can be said for regime change.
The United States tried to implement the concept of rollback only once during the Cold War, when General Douglas MacArthur had the North Korean army on the run in 1950. Ignoring President Truman's orders, MacArthur sent American troops to the North Korean border with the People's Republic of China. This triggered a massive intervention by Chinese Communist troops. American forces were overrun, with many killed or captured.
Eventually, the Korean conflict turned into a stalemate. Perhaps we learned a lesson about rollback from that experience. In any case, the United States never attempted rollback again. When advisers clamored for rollback, American presidents resisted and averted potential catastrophes.
What we know about the strategy of rollback indicates we should approach the concept of regime change with extreme caution. It should be seen not only as a last resort but also as one with important disadvantages. Perhaps the most serious disadvantage is that President Bush's policy of regime change violates international law. Pre-emptive war is merely a euphemism for aggression.
The dangers of serious harm to the United States have diminished considerably since the collapse of the Soviet Union. Ours is still a world that harbors weapons of mass destruction, with many people busy dreaming up ways to turn the stuff of daily life into weapons. We cannot possibly predict what American attempts at regime change might set off. In what some consider reckless attempts by the Bush administration to head off myriad threats, the administration may trigger something far worse than the immediate danger.
During the Cold War, rollback was a dangerous fantasy we fortunately tried only once. Its 21st-century cousin, regime change, is an equally dangerous delusion, even when the United States believes no enemy is powerful enough to challenge its superior weaponry. We no longer face atomic retaliation. Nonetheless, there is no reason to risk provoking new forms of retaliation in our rush to use force to reorder the world.
This piece was distributed for non-exclusive use by the History News Service, an informal syndicate of professional historians who seek to improve the public's understanding of current events by setting these events in their historical contexts. The article may be republished as long as both the author and the History News Service are clearly credited.
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Ben Cosin - 11/26/2002
I was unaware until a few weeks ago tat many people believed that Saddam or the Iraqi Ba'th Socialist Party were in any way supported by the CIA. Nor is this possiblity mentioned directly in Republic of Fear by 'Samir al Khalil' now revealed as Kanan Makiya, adviser to Chalabi. Makiya argues strongly and convincingly that the Iraqi Commuist Party was on an upaward curvein the 1940's and 1950's, and this in itself suplies a good reasn for the CIA to take an active interest. Moreover, Makiya's explanation of the decline fo the ICP (esp pp 240-1) is rather unconvincing, basing itself as it sdoes in the idea that the class structure of Iraq was somehow swamped by 'massification' - a cause itself unexplained. Saddam's trusting attitude to Glaspie in July 1990 might supply minor confirmatory evidence.
More generally, if the CIA wasn't and isn't involved in a good deal of regime change, or installation of governments friendly to US imperialism, from Italy 1948 through Iran/Persia 1954 etc, what is the money being spent for?
Ben Cosin
Mike Tennant - 11/25/2002
Your argument, of course, presumes that Iraq is poised to strike the U. S., of which we have seen no evidence. The only "evidence" we have is the word of the president. No other country except Britain, which has become a U. S. yes-man in recent years, seems terribly concerned about Saddam Hussein. Oh, wait: Israel is quite concerned AND has a very powerful lobby in Washington. Perhaps we are going in to do Sharon's dirty work for him.
Saddam Hussein has never threatened us, and he knows he'd be foolish to do so. He certainly wouldn't use nukes against us; and furthermore, he wouldn't give them to al-Qaeda, his enemy, who just might use them against him.
North Korea and China, on the other hand, do have nukes (and we know this not just because the prez says so), and they have issued actual threats toward the U. S. Why does our brave president not suggest we wipe out their leaders and install puppet regimes? The fact that he does not do so indicates that the attack on Iraq has nothing to do with its posing a danger to us.
Herodotus - 11/25/2002
This historian, who is well briefed in the history of the CIA's involvement in other countries from Iran to Panama, is not aware of any widespread belief that Hussein before 1979 was a 'creature' of the CIA other than on the conspiracy fringe.
One might expect a simple request for solid academic work detailing the subject could be greeted with anything but the rancor and venom apparent in this thread.
Apparently this is all about scoring political points and not advancing serious inquiry. Too bad.
William H. Leckie, Jr. - 11/23/2002
Somebody's been watching too much USA or Lifetime or too many re-runs of Lethal Weapon Nth or Chuck Norris kick-flicks.
Tom Kellum - 11/21/2002
Does the historian who calls himself Herodotus have any reason to believe there has been CIA involvement in setting up heads of state in ANY countries? Or is it his view that such things simply don't happen?
Well, so President Bush did an "interview" with the Washington Post and explained what motivates his administration. Nice to know that we have a president who is so forthcoming. Think he's that way out of some lingering guilt over the manner in which he came to be president? Or, is it simply in the genes of that fine Bush aristocracy to always act honorably and tell the truth?
Oscar Chamberlain - 11/20/2002
Unfortunately, paying off warlords seems like a real possibility.
Nothing about our actions in Afghanistan suggests any willingness to pay the price of occupation. The only reason that we might try harder in Iraq is that not doing so could destabilize the Kurdish situations. That could create repercussions simply in Turkey.
Instability would also make oil investors a bit more leary about putting money in.
So who knows. If it takes stability to get oil and democracy to get stability, Bush may become the Wilsonian he pretends to be.
William H. Leckie, Jr. - 11/20/2002
I'm surprised that a knowledgeable historian isn't familiar with the published literature, but start with Peter Mantius, Shell Game (St. Martin's, '95)and move through the literature to Con Coughlin's King of Terror (Ecco, '02). There's older stuff, look it up. In any case, the agency's role in Saddam's rise to power is not a new canard floated by me. For a short A/V course, hit the Frontline documentary installment, "Saddam's Survival" which is just a click away at http://pbs.org/wgbh/pages/frontline/
Alas, to my knowledge nothing as been declassified I'm aware of, and spooks generally don't like to make tracks, or I'd refer you to paperlessarchive.com or somesuch. I doubt Saddam would've bragged about his being a CIA protege, and perhaps one reason he's managed to eliminate so many of his early-days Ba'ath associates is that when he was a comer as Ba'ath security chief they knew who was footing his bills--sheer speculation there, of course.
As for the administration's "idealism," hey! Whatever. Maybe they really are as nuts as they seem. Let me in turn ask: Just who's gonna pay for this war to bring democracy to Mesopotamia, if we're uh-gonna keep cutting taxes for the upper 1%, enshrine offshore benefits to corporations in a "homeland security" act, repeal the estate (not "death" tax), and as budget deficits balloon with a weak economy? And will we (with our lousy recent track record in Afghanistan and despite awful analogies to Japan and Germany post-WW2) stick around to clean up the mess, or just pay off Kurd and Shi'a warlords? Oh--whatever happened to the hunt for Osama, when this week's Time (no left-wing rag) reports that there's an al Qaeda stronghold we can't even enter, and Pakistan's Northern Frontier has gone Islamist? If we do as good a job in Iraq as we have in post-Taliban Afghanistan, maybe the Bushites' heads are up in the clouds--or somewhere else darker?
Herodotus - 11/20/2002
As a historian, I ask for a precise citation of the suggestions that the CIA set up Hussein before and during his rise to power in the 1970s....before the Iranian revolution.
As for the claims that this is really about imperial basing, fellow historians are invited to see the excerpted interview with Bush in the November 19 Washington Post. From it is room to believe that more than just realism motiviates this administration.
William H. Leckie, Jr. - 11/19/2002
There is reasonable suspicion that our own CIA helped set Saddam up in power as part of a Cold War "regime change," and despite the denials of such as Rummy that we didn't it's also true that via cut-outs such as Egypt we supplied him with military equipment during the Iran-Iraq war, turned a blind eye to his use of chemical weapons, and provided him with precursors for biological agents.
It is also true that US firms such as Halliburton, during Our Veep's tenure as its CEO, did business with Iraq through foreign subsidiaries to rebuild infrastructure.
However, there is as of today no--I mean absolutely no--hard evidence (therefore as yet no truth value to assertions that he does) that he possesses those now boringly acronymic WMD's. And I suspect that the motivations behind the administration's bellicosity--as analyzed in a recent Village Voice column--actually revolve around finding an imperial base from which to pursue South and Central Asian objectives while taking heat off the House of Sa'ud. The road from Riyadh to Qatar leads to Baghdad? Let's cut the nonsense about the demonic threat posed by a thug we protected during and after he was in an Iraqi prison and helped bring to power--a student of Stalin who also was a vicious liquidator of the Iraqi Left when it was convenmient for us. It is not "absurd" to wait until we are "sure" he has nasty things, and assess the Shrub's objectives in terms of the Realpolitik (however grounded in reality) they are premised.
And perhaps Saddam's presence should serve as a reminder of what past meddling based on right-wing ideology can lead to. And this time, instead of covert operations and funneling cash and whispering in people's ears, we're contemplating a major war, with all the death and destruction--and unforseen consequences--that come with it. My grand-daddy once wisely told me, "Never argue with a fool, because after awhile nobody'll be able to tell the difference," but the stakes are too high to ignore idiocy in power and the children of Hamlin who follow its piping.
James Thornton - 11/19/2002
There is no major power to support Iraq as China did North Korea.
Secondly, let's say your family lives in a dangerous neighborhood. Within that neighborhood a serial killer and rapist has began to target your apartment building. The busy body lady on the first floor who chairs the neighborhood watch telephones to let you know that through the grapevine she has learned that the killer will be coming for you soon. You don't have the money to move, and the police won't respond to this neighborhood. You are armed to the teeth. What do you do to defend your home? Do you wait for the killer to strike when he has initiative, or do you organize a posse and use street justice to take care of business?
don kates - 11/18/2002
This article unfortunately confuses two completely different points. The author is right that it is no business of the U.S. to decide how Iraq is ruled; and even if it were our business it would not be possible to force institutions rooted in our culture on Iraq.
But that in no way invalidates the exigent necessity of keeping weapons of mass destruction (WMD) from a maniacal mass murderer like Saddam. It is absurd to argue that we should wait until we are sure Saddam has WMDs. Let us instead take the vital step of disarming him before he has them. And if that results in a new government in Iraq, why would we shed tears over that?
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Quinacridone Sienna (PO48 PR209 PY150) 5ml Tube, DANIEL SMITH Extra Fine Watercolor
The ultimate low-staining glazing pigment, certainly finer than any Burnt Sienna. For the traditional and purist watercolor painter, Quinacridone Sienna divides yellows from reds, falling on the orange line. Its place on the color chart makes Quinacridone Sienna a complement-free pigment, easy to modify without revealing a hidden gray.
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Tenofovir, Emtricitabine and Efavirenz Late Switch to a Single Pill: Patients' Opinion Survey
This study has been completed.
Policlinique Médicale Universitaire
Centre Hospitalier Universitaire Vaudois
Swiss HIV Cohort Study
Gilead Sciences
Information provided by (Responsible Party):
Marie Schneider, Policlinique Médicale Universitaire
ClinicalTrials.gov Identifier:
First received: March 24, 2011
Last updated: December 21, 2015
Last verified: December 2015
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Detailed Description:
The purpose of this study is to assess adherence, tolerability and satisfaction of each eligible HIV subjects switching from a two- or three-pill tenofovir-emtricitabine-efavirenz (TDF-FTC-EFV) to a one-pill TDF-FTC-EFV treatment.
|HIV Infection
|Study Type:
|Study Design:
|Observational Model: Case-Only
Time Perspective: Prospective
|Official Title:
|HIV-positive Patients Under Tenofovir, Emtricitabine and Efavirenz Therapy Switching From a Two-pill Regimen to a Single Pill Regimen: Patients'Opinion Survey
Resource links provided by NLM:
MedlinePlus related topics: HIV/AIDS
Drug Information available for: Emtricitabine Tenofovir EfavirenzU.S. FDA Resources
Further study details as provided by Marie Schneider, Policlinique Médicale Universitaire:
Primary Outcome Measures:
- Patient adherence [ Time Frame: V0, V1, V2 ]by questionnaire in both subgroups and by MEMS data in the adherence subgroup
- Adverse events and symptoms [ Time Frame: V0, V1, V2 ]by questionnaires
- Treatment management [ Time Frame: V0, V1, V2 ]Treatment management according to meals, timing, disruptive daily schedule By questionnaire
- Patient satisfaction of the switch [ Time Frame: V1, V2 ]By questionnaire
Secondary Outcome Measures:
- Impact of switch on clinical outcomes [ Time Frame: V0, V1, V2 ]Clincal outcomes = viral load, CD4 count, resistance, EFV blood level. By medical file
- Patients' acceptance of switch [ Time Frame: V-1 ]
|Study Start Date:
|July 2010
|Study Completion Date:
|February 2012
|Primary Completion Date:
|October 2011 (Final data collection date for primary outcome measure)
Each eligible patient will be screened from de SHCS database. Each refusal and drop-out will be documented. A pre-visit (V-1) will be scheduled for informed consent, V0 for inclusion (V-1 and V0 may occur on the same day), V1 one month post-inclusion and V2 4 to 7 months post-inclusion. V0, V1 and V2 will be planned during regular medical visits.
Eligible patients either get their cART in their usual pharmacy according to standard of care, or take part in a routine adherence-enhancing program(adherence subgroup)run by the pharmacists of the outpatient medical clinic.
In the adherence subgroup, adherence is assessed electronically by MEMS (Medication event monitoring system) monitors on a regular basis.
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
|Sampling Method:
|Non-Probability Sample
Study Population
Patients under TDF-FTC-EFV followed up at the Service of Infectious Disease of the University Hospital of Lausanne and enrolled in the Swiss HIV Cohort Study (SHCS) Adherence subgroup: patients enrolled in the HIV adherence program at the pharmacy of the Department of Ambulatory Care & Community Medicine in Lausanne.
Inclusion Criteria:
- patients under TDF-FTC-EFV
- followed up at the Service of Infectious Disease of the University Hospital of Lausanne
- enrolled in the SHCS
Exclusion Criteria:
- patients receiving TDF-FTC-EFV in combination with other ARTs
- patients under TDF-FTC-EFV for less than 3 months
- patients not fluent in French
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01322932
Please refer to this study by its ClinicalTrials.gov identifier: NCT01322932
|Centre Hospitalier Universitaire Vaudois et Policlinique Medicale Universitaire
|Lausanne, Vaud, Switzerland, 1011
Sponsors and Collaborators
Policlinique Médicale Universitaire
Centre Hospitalier Universitaire Vaudois
Swiss HIV Cohort Study
Gilead Sciences
|Study Chair:
|Matthias Cavassini, M.D
|Centre Hospitalier Universitaire Vaudois
|Principal Investigator:
|Marie-Paule Schneider, PhD
|Policlinique Médicale Universitaire
|Study Chair:
|Olivier Bugnon, Professor
|Policlinique Médicale Universitaire
|Principal Investigator:
|Aurélie Gertsch, PhD Student
|Policlinique Médicale Universitaire
More Information
Keywords provided by Marie Schneider, Policlinique Médicale Universitaire:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on September 21, 2017
|Responsible Party:
|Marie Schneider, Pharmacist, PhD, Policlinique Médicale Universitaire
|ClinicalTrials.gov Identifier:
|NCT01322932 History of Changes
|Other Study ID Numbers:
|Study First Received:
|March 24, 2011
|Last Updated:
|December 21, 2015
Keywords provided by Marie Schneider, Policlinique Médicale Universitaire:
Medication Adherence
HIV Infection
efavirenz, emtricitabine, tenofovir disoproxil fumarate drug combination [Substance Name]
Patient Satisfaction
tenofovir disoproxil fumarate
Additional relevant MeSH terms:
HIV Infections
Lentivirus Infections
Retroviridae Infections
RNA Virus Infections
Virus Diseases
Sexually Transmitted Diseases, Viral
Sexually Transmitted Diseases
Immunologic Deficiency Syndromes
Immune System Diseases
Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination
Efavirenz, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination
Antiviral Agents
Anti-Infective Agents
Reverse Transcriptase Inhibitors
Nucleic Acid Synthesis Inhibitors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Anti-Retroviral Agents
Anti-HIV Agents
Cytochrome P-450 CYP2C9 Inhibitors
Cytochrome P-450 Enzyme Inhibitors
Cytochrome P-450 CYP2C19 Inhibitors
Cytochrome P-450 CYP2B6 Inducers
Cytochrome P-450 Enzyme Inducers
Cytochrome P-450 CYP3A Inducers
ClinicalTrials.gov processed this record on September 21, 2017


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Posted 6 years ago
(312 items)
Here's a pic of a sign I picked up a earlier this summer,just got around to framing it. The frame keeps it from any further deterioration,and matches the rest of the garage,which I've been busy finishing. The sign is not in the best of shape, but they are fairly rare, and it's got great character!


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As the popularity of lacrosse has grown and expanded, Gillette Stadium has been proud to open its gates to several landmark events during the lacrosse season. Gillette Stadium launched its title as a neutral playing field in 2008 during a college lacrosse doubleheader featuring Cornell vs. Harvard and Bryant vs. Merrimack. Since that game, Gillette Stadium has hosted upwards of two major lacrosse events per season.
Gillette Stadium has been the site of lacrosse doubleheaders, most recently playing host to the first-ever women's games on the field. Beginning in 2010, the New England Lacrosse Classic has been held at Gillette Stadium. The annual event features two head-to-head battles of some of the northeast's greatest competitors.
In 2011 Gillette Stadium hosted the NCAA Division I Men's Lacrosse Quarterfinals, drawing the second largest crowd in NCAA history, setting the tone for the Championships which advanced to Baltimore, Maryland.
The NCAA has brought the culmination of the college lacrosse season to Gillette Stadium four times. The NCAA Men's Lacrosse Championships were played in Foxborough in 2008, 2009, 2012 and most recently in 2017. In 2017 Gillette Stadium became the first venue to host both the Division I Men's and Division I Women's Championships. Gillette Stadium will host the Men's Championships again in 2018. The battles of the bests have drawn record crowds with fans from across the country.
In addition to college events, Gillette Stadium has also hosted several high school games, youth clinics, and coaches clinics in its efforts to promote the game.
Gillette Stadium is proud to have hosted these historic events and continues to grow its lacrosse tradition. Check back frequently and connect with Gillette Stadium Lacrosse on Facebook and Twitter to find out when the next lacrosse games will be featured at Gillette Stadium.
Please click on the following links for more information:


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Lost Planet 2, Evangelion beauties, more...
San Diego Comic-Con coverage brought to you by Collectibles Insurance, Big Bad Toy Store, Sekaido, and Monkey Depot.
Beyond Star Wars, DC, and Marvel, Koto had a wide range of great Japanese products on display at their booth. From the Neon Genesis Evangelion beauties in their plug suits to the Lost Planet 2 collection, One-Shot Bug Killer, chibi Patlabor, models, and Bishoujo statues, there was something there for everyone.
Check out our complete photo gallery HERE!
- Scott Rubin


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For years, California motorcyclists have enjoyed the benefits of a non-law. California is the only state in the nation that doesn't legally prevent lane splitting, or traveling between lanes of stopped and slower-moving traffic, but there haven't been hard and fast rules governing the practice.
Until now.
The California Highway Patrol has, for the first time, published lane-splitting guidelines on its website "to dispel misinformation," said Todd Kovaletz, public information officer for the Santa Ana bureau of the California Highway Patrol. "There are no new laws, simply clarification for what is already out there."
The state agency has never taken a position on the controversial practice that motorcyclists perceive as convenient and other vehicles see as a hazard.
The new guidelines advise motorcyclists to travel no more than 10 mph faster than other traffic, to refrain from splitting lanes when traffic is flowing at 30 mph or faster, to restrict their lane splitting to the space between the first and second lanes and to consider the total environment in which they are lane splitting, including the width of traffic lanes, the size of surrounding vehicles and the conditions of the roadway, weather and lighting.
In the works for almost two years, the guidelines were developed as a result of the state's Strategic Highway Safety Plan, for which the California Highway Patrol and Department of Motor Vehicles collaborated to improve motorcycle safety. According to the National Highway Traffic Safety Administration, motorcyclists are 39 times more likely than passenger-car occupants to die in traffic crashes per vehicle mile traveled.
Despite the new guidelines, the Motorcycle Safety Foundation, in Irvine, does not promote lane splitting. The MSF subcontracts safety training through the California Highway Patrol at 131 sites throughout the state as parts of the California Motorcyclist Safety Program.
"One of the greatest allies you have when riding a motorcycle is time and space," said MSF vice president, Robert Gladden. "If you're lane sharing, you're reducing the time you have to react to obstacles in the roadway or what other drivers or riders are doing."
Even so, 87 percent of California's motorcycle riders say they split lanes, according to the state's Office of Traffic Safety.
Contact the writer: email@example.com or Twitter @OCRcarpenter


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The American Association of Exporters and Importers (AAEI)'s 92nd Annual Conference and Expo, themed, "Globablization: Policy and Practice," will be held from June 16-18, 2013 at the Omni Shoreham Hotel in Washington DC. The AAEI conference will bring together leading experts in the field, including representatives from government, industry, and trade associations.
Planning to attend the AAEI 92nd Annual Conference and Expo and looking for a unique place to stay in Washington DC? Try American Guest House, a Dupont circle bed and breakfast, located near the Omni Shoreham. Enjoy freshly prepared breakfast and baked goods in the morning, and still arrive in plenty of time for the conference! Our DC accommodations are located a short walk or bus ride from the Omni, and our individualized rooms and personalized service, will help this feel like your "home away from home."
View Directions to the Omni Shoreham Hotel from the American Guest House in a larger map
Jennifer, Innkeeper
American Guest House in Washington DC


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A man facing a second trial for rape and making threats to kill has been found dead in his Chippenham home.
Michael Frederick Unwin was found in his house on Oak Road on Sunday.
Police described the 49-year-old's death as sudden and said they are not treating it as suspicious.
Mr Unwin appeared at Swindon Crown Court for trial in February this year, accused of raping and threatening to kill a mother in her home, allegations which he denied.
The jury failed to reach verdicts and a retrial was scheduled for October 13.
Four police cars and an ambulance were seen outside Mr Unwin's house on Oak Road, off Drake Crescent, shortly after 1pm on Sunday.
South Western Ambulance Service said they were called at 1.12pm but a man was dead on arrival.
The matter has been referred to the Independent Police Complaints Commission as a death following police contact.
A police spokesman said: "We were called to a residential address on Oak Road shortly after 1pm on May 11. A man was found dead inside the property.
"It is being treated as a non-suspicious sudden death.
"Wiltshire Police can confirm the body of the male has been formally identified as 49-year-old Michael Frederick Unwin.
"It would be inappropriate to comment further at this stage due to the ongoing process."
During the five-day trial in February, the woman said she woke in the early hours of the morning, in December 2012, to find Mr Unwin standing over her bed.
She said he got in through a window and, after threatening her, dragged her to the front room and raped her while her toddler slept in a nearby room.
Mr Unwin insisted the woman had consented to sex and had sent him a text message inviting him.
She said he had taken her mobile phone and sent a text message to his.
An inquest into the death has not yet been opened.
Police said that a report will be prepared for the coroner for Wiltshire and Swindon and an inquest was likely to be opened in Salisbury this week.


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Beacon Staff
Teresa Shumaker won first place in the sports photographer category in the National Newspaper Association Publishers Auxiliary Awards for the quarter ending Sept. 15. The photo was taken at Shoreline Rodeo events this past July. A cowboy jumps off his horse and grabs the young steer by the horns in the steer wrestling competition. Teresa Shumaker photo.


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