text:
Conjugate And Polysaccharide Vaccines Compared With Polysaccharide Vaccine In Hiv-Infected Adults
Recruitment status was: Recruiting
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|Pneumococcal Vaccines HIV HIV Infections
|Biological: Prevenar and Pneumo23
|Phase 3
|Study Type:
|Study Design:
|Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Prevention
|Official Title:
|A Sequential Vaccination Strategy With Conjugated and Polysaccharide Pneumococcal Vaccines Compared With Polysaccharide Vaccine in HIV- Infected Adults.
- Antibody response in terms of antibody concentration at 4,8,48 and 69 weeks of vaccination [ Time Frame: 4, 8, 48 and 96 weeks of vaccination ]
- Avidity of the antibodies induced in the two vaccination groups before and at 4 ,8 , 48 and 96 weeks of vaccination [ Time Frame: 4 , 8 ,48 and 96 weeks after vaccintation ]
- safety of both vaccines [ Time Frame: 3 days ]
- risk factors associated to a good vaccine response [ Time Frame: 8 weeks, 48 weeks, 96 weeks ]
- opsonophagocytic activity against the seven polysaccharides before, and after 4,8,48 and 96 weeks of vaccination [ Time Frame: 4,8,48 and 96 weeks ]
|Estimated Enrollment:
|Study Start Date:
|December 2007
|Estimated Study Completion Date:
|April 2010
|Estimated Primary Completion Date:
|April 2008 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: two vaccines
people allocated to arm two vaccines will receive one dose of heptavalent pneumococcal conjugate vaccine at day 0 and 23-valent polysaccharide vaccine at week4 , 110 HIV-infected people will be included Intervention: administration of two vaccines
Biological: Prevenar and Pneumo23
Two vaccines: participants will receive via intramuscular in deltoid one dose of conjugated heptavalent vaccine at day 0 (Prevenar, Wyeth-lederle)and one dose of 23valent polysaccharide vaccine (Pneumo23, AventisPasteur)at week4 One vaccine:participants will receive only one dose of 23valent polysaccharide vaccine at day 0.
Other Names:
Experimental: One vaccine
people allocated to arm one will receive only one doses of pneumococcal polysaccharide 23-valent vaccine. 110 HIV-infected adults will be included in this arm Intervention: administration of one vaccine
Biological: Prevenar and Pneumo23
Two vaccines: participants will receive via intramuscular in deltoid one dose of conjugated heptavalent vaccine at day 0 (Prevenar, Wyeth-lederle)and one dose of 23valent polysaccharide vaccine (Pneumo23, AventisPasteur)at week4 One vaccine:participants will receive only one dose of 23valent polysaccharide vaccine at day 0.
Other Names:
Detailed Description:
Randomised study comparing two pneumococcal vaccination strategies in HIV-infected adults with moderate immunossupression (CD4 between 200 and 500 cells/uL and viral load under 5logs), one with conjugated heptavalent vaccine(Prevenar, Wyeth-Lederle) followed by polysaccharide vaccine 4 weeks after (Aventis-Pasteur), and two with one dose of polysaccharide vaccine. A sample of 220 HIV-infected adults will be randomised to receive twe strategy one(110 patients) one dose of heptavalent conjugated vaccine at day 0 and one dose of polysaccharide vaccine at week 4 (in deltoid muscle); or strategy two (110 patients) one dose of polysaccharide vaccine at day 0. Secondary effects to the vaccines will be evaluated by phone interview 3 days after vaccinations.
Blood samples will be taken at day 0(before the first vaccine), at week 4 before the polysaccharide in the group one, and 4 weeks after the polysaccharide in the group two) and at week 8 in the group one, and at weeks 48 and 96 in both groups Antibody concentration , avidity, and opsonophagocytic killing activity will be measured in all the samples for serotypes 4,14,19F,23F,6B,18C,9V.
Antibody concentration , avidity, and opsonophagocytic killing activity will be compared between both vaccine groups, and between prevaccination and at 4,8, 48 and 96 weeks of vaccination. Risk factors associated to good antibody response (antibody duplication and antibody duplication plus achieve a level above 1ug/ml)will be measured at 8, 48 and96 weeks.
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- HIV-infected adults with CD4 between 200 and 500 cels/ul and viral load under 5 logarithm
Exclusion Criteria:
- previous pneumococcal vaccine, pregnancy, advanced renal or liver disease, other vaccine or antibiotics 6 weeks before, other immunosuppression, immunoglobulins or investigation drugs
Please refer to this study by its ClinicalTrials.gov identifier: NCT00999739
|Contact: maria penaranda, physician
|Contact: antonio payeras, physician
|Hospital Son Dureta
|Palma de Mallorca, Illes Balears, Spain, 07014
|Contact: Maria Penaranda, physician 0034971175371 email@example.com
|Principal Investigator: maria penaranda, physician
|Hospital Son Llatzer
|Palma de Mallorca, Illes Balears, Spain, 07014
|Contact: antonio payeras, physician 0037971175371 firstname.lastname@example.com
|Principal Investigator: antonio payeras, physician
|Principal Investigator:
|maria penaranda, physician
|Hospital Son Dureta
|Principal Investigator:
|antonio payeras, physician
|Hospital Son Llatzer
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
|Responsible Party:
|Maria Penaranda, Hospital Son Dureta
|ClinicalTrials.gov Identifier:
|NCT00999739 History of Changes
|Other Study ID Numbers:
Maria Penaranda
|Study First Received:
|October 21, 2009
|Last Updated:
|November 6, 2009
Keywords provided by Hospital Universitari Son Dureta:
pneumococcal vaccines
antibody response
antibody affinity
Antibody formation
Additional relevant MeSH terms:
HIV Infections
Lentivirus Infections
Retroviridae Infections
RNA Virus Infections
Virus Diseases
Sexually Transmitted Diseases, Viral
Sexually Transmitted Diseases
Immunologic Deficiency Syndromes
Immune System Diseases
Heptavalent Pneumococcal Conjugate Vaccine
Immunologic Factors
Physiological Effects of Drugs
ClinicalTrials.gov processed this record on September 21, 2017


text:
OROVILLE — Stan and Rita DeLong thought their three dogs would be safe on Thanksgiving Day in the backyard of their business on Baldwin Avenue near Yard Street.
"The dogs have always been safe in the yard," Rita DeLong said.
They put the dogs in the yard that has a tall fence with barbed wire around the top at DeLong's Heritage Heating in the morning,
When they came home at 5 p.m. one dog had been fatally wounded and another dog had scratch marks on its chest.
"At first I thought it might have been a dog that jumped over the fence," Rita DeLong said.
They took the dog to a veterinarian in Chico who told them that it could not have been a dog that killed their dog.
The wounds came from an animal with very large canine teeth, and the punctures were four inches apart, she said.
In addition, the scratch on the other dog's chest was consistent with a mountain lion wound.
Northwest Society for the Prevention of Cruelty to Animals humane officer Michael Hicks said it was a very large animal that killed the 70-pound boxer on Baldwin Avenue.
While it appeared to be the work of a mountain lion, Hicks said they aren't 100 percent sure.
The California Department of Fish and Game told him it's possible, Hicks said.
Hicks said because the animal came into to town in a very populated area, he wanted to make people announce it to the public.
"We don't want people to panic but to just be aware of their surroundings."
While mountain lions are primarily nocturnal, they do come out in the daytime, he said.
The property on Baldwin butts up against the railroad tracks and is only a quarter of a mile from the wildlife area.
"These animals do exist in this area," Hicks said. "It's their habitat."
And every year, people do see mountain lions.
Cold weather can make prey sparse for mountain lions who can move closer to town.
About three days after the dog attack, the neighbor behind the Heritage Heating property reported something had eaten his chickens.
Hicks said a couple of years ago, a mountain lion was killed at a house on Perkins Avenue.
TJ Jensen, a resident of the Long Bar area, said a friend had come upon two devoured bucks and one deer while hiking recently. A neighbor also caught the image of a black bear on home security cameras as it walked past the house to the river.
Hicks said if people spot mountain lions, they should not turn and run. They should yell, throw things and try to appear large and menacing.
Typically mountain lions stalk their prey, so they can frequently travel on trails where they can walk quietly, he said.
Humans are not the cat's ideal prey, and they usually like to take prey without a confrontation, he said.
They attack humans very quickly from behind, and bite through the base of the neck.
Hicks has spotted several lions in this area and near his house near Feather Falls Casino. He said they all ran away when they saw him.
People should report mountain lion or other predatory large animal encounters to the Oroville Police department, the SPCA at 533-7676 and California Department of Fish and Game.
Carcasses of dead animals should also be reported to the SPCA so they can check out they killings, he said.
Staff writer Mary Weston can be reached at 533-4415 or firstname.lastname@example.com.

subset: commoncrawl


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The Crown Hotel3
Crown Hotel,, Exford, TA24 7PP
Price FromView Rooms
- Excellent
- 1 guest reviews
"The accommodation was comfortable and friendly with excellent food and service. The room was a good size, with plenty of tea and coffee faci..."
About the hotel
The warmest of welcomes awaits everyone who steps over the threshold of this renowned 17th Century family run Coaching Inn.
We are situated amongst 3 acres of gardens in the centre of Exford, one of Exmoor's prettiest villages, surrounded by stunning countryside where Exmoor ponies, red deer and birds of prey roam free.
The elegant award winning restaurant has a traditional feel yet with a modern twist and has an intimate and relaxed atmosphere.
It has a reputation both locally and nationally. The cosy country bar provides diners with more informal dining, serving hearty home cooked meals alongside real ales and local tales! All our meat and fresh fish are locally sourced with organic and free range being a main priority when sourcing our goods. Not forgetting our fine wine list with wines chosen to compliment our dishes and excite the palate.
Guest comfort is a main priority at The Crown. We aim to make your stay as relaxed and enjoyable as possible. The unique friendly atmosphere ensures you feel part of the family. Our rooms are all individually styled and tastefully decorated with modern amenities; all are ensuite. The lounge is the ideal place to enjoy a hot buttered crumpet in winter beside the roaring log fire and our gardens in summer are the ideal place to devour one of our delicious cream teas.
The Crown Hotel is pet friendly and dogs are more than welcome to bring their well behaved owners! We also have stables available for those who wish to explore Exmoor on horseback.
For that special reunion, birthday, anniversary or intimate wedding The Crown Hotel is available for hire.
Situated at the heart of the Exmoor National Park, we are ideally placed for taking advantage of the wonderful coutryside and coastline of Exmoor. Activities on Exmoor include cycling, walking, fishing, horse riding and trekking, shooting, hunting and wildlife watching.
There's something for everyone at The Crown Hotel.
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Facilities Show/hide
- Main
- Hotel Non-Smoking Throughout, Iron And Board In Each Room, Limited Hours Room Service, Wake Up Call Available
- Parking
- Car parking available onsite
- Dining
- Restaurant, Bar
- Business
- Wi-Fi Available In Public Areas
Can't find the facilities you're looking for?
- Call us on 0333 300 1007 and we'll help find the perfect hotel for you
- Call
Useful Info Show/hide
- Between 15:00 and 23:00
- By 11:00 hours
- Up to 17 years old
- The price shown is based on the occupancy and dates you have searched for. Prices and availability are subject to change based on the arrival date, number of nights and occupancy searched for. All prices are inclusive of all local taxes.
- Pets are not allowed
Customer Reviews
Our reviews are from genuine LateRooms.com customers. We verify that the customer has stayed before leaving a review.
100% would recommend it to a friend
Customer service
Food quality
Room quality
Comfortable and friendly
The accommodation was comfortable and friendly with excellent food and service.
The room was a good size, with plenty of tea and coffee faci...
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text:
condominiums below are located at Sand Dollar Condo in Crescent Beach Florida. If you are
interested in finding the best buys on condos at Saint Augustine or
Crescent Beach Florida contact us at the number below. We have helped
folks find condos for sale since 1989.
Florida Beachfront Condos
Ocean Racquet Ocean Gallery Condo Sea Place Condo Four Winds Condo Ocean Village Club Colony Reef Club
Anastasia Condo Barefoot Trace Hibiscus Condo Sand Dollar Condos Tradewinds Condo
Summerhouse Condo St Augustine Beach condos Crescent Beach condos Waterfront condos Bank owned condos
Copyright Landmark Realty, Inc.
All Rights Reserved
The data relating to real estate for sale/lease on this web site come in part from a cooperative data exchange program of the multiple listing services (MLS) in which this real estate firm (Broker) participates. The properties displayed may not be all of the properties in the St. Augustine MLS's database, or all of the properties listed with Brokers participating in the cooperative data exchange program. Properties listed by Brokers other than this Broker are marked with either the listing Broker's logo or name or the MLS name or a logo provided by the MLS. Detailed information about such properties includes the name of the listing Brokers. Information provided is thought to be reliable but is not guaranteed to be accurate; you are advised to verify facts that are important to you. No warranties, expressed or implied, are provided for the data herein or for their use or interpretation by the user. The Florida Association of REALTORS® and its cooperating MLS do not create, control or review the property data displayed herein and take no responsibility for the content of such records. Federal law prohibits discrimination on the basis of race, color, religion, sex, handicap, familial status or national origin in the sale, rental or financing of housing.


text: Peterson: World Cup success could have big implications Michael Peterson May 12, 2014 0 Comments Twenty years can certainly change a lot in sports. Flash back 20 years from today and the United States men's soccer team had never qualified for more than two World Cups in a row. In fact, prior to... Read More »


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EASTPOINTE, Mich. - Eastpointe police have released surveillance pictures of two people who robbed a ChecknGold on Gratiot Avenue Wednesday afternoon.
Police said the two entered the store just before 3 p.m. and one of them brandished a black semi-automatic pistol, forcing an employee to a back room and demanding money.
Police said the employee handed over an undisclosed amount of money and was then pushed to the ground by one of the robbers.
A K-9 was used to track the robbers, but they weren't found.
Police said they think the robbers had a car waiting for them nearby.
Police descriptions of robbers:
1.White man in his late teens or early 20s, about 5 feet 9 inches tall, thin build, had a black semi-automatic pistol. He was wearing a green jacket with light blue jeans and wore a white shirt or cloth over this head and face.
2. White man in his late teens or early 20s, about 5 feet 11 inches, thin build. He was wearing a red, white and black plaid hoodie with blue jeans and wore a brown or black shirt over his face.
Copyright 2012 by ClickOnDetroit.com. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


text:
Internal Affairs Squad/Security Squad
2714 Union Extended
Memphis, TN 38104
Fax: 901-458-9146 or 901-458-9157
Suite 600 - IAB
Suite 700 - Security Squad
Inspectional Services is made up of the Internal Affairs Squad and the Security Squad. Inspectional Services conducts all internal investigations involving police personnel, as well as, other sensitive investigations. Officers assigned to these units are appointed by the Director of Police and are considered to be highly experienced investigators.
Internal Affairs
The purpose of the Internal Affairs Squad is to define responsibilities and establish procedures for sworn members of this department for dealing with observed or reported allegations or misconduct. Internal Affairs investigates all complaints lodged against police personnel. These complaints can range from verbal abuse to brutality. The majority of these complaints fall under three categories: Personal Conduct, Use of Force and Arrest, and Duty Performance.
Security Squad
The Security Squad investigates all shooting incidents involving police officers and any complaints regarding possible criminal misconduct against employees. These investigations include accusations against officers, city employees from various departments, and other administrative investigations.
The Security Squad is also responsible for teaching Deadly Force lectures at the Training Academy for new police recruits and during In-Service Training for veteran officers. Their Deadly Force lecture was also part of the training received by all citizens enrolled in the Citizen's Police Academy.


text:
Note: This item is more than 13 years old. Please take the publication date into consideration for any date references.
Print – Plain Text – Permalink
News Release
Media Contact: TPWD News, firstname.lastname@example.com, 512-389-8030
June 21, 2004
Outbreak of Exotic Virus Hits South Texas Shrimp Farms
AUSTIN, Texas — Four South Texas shrimp mariculture farms have been quarantined and are now prevented from discharging wastewater after tests confirmed that the exotic shrimp illness Taura Syndrome Virus killed shrimp at the facilities last week.
While the virus is not a threat to human health, Texas Parks and Wildlife Department and other authorities are concerned about what might happen to wild, native shrimp stocks if the illness broke out in public waters.
The Taura syndrome was first detected in Texas shrimp farms in 1995. In 1998, TPWD helped lead efforts to set new regulations for shrimp farm disease monitoring and response, working with the industry and other agencies. This includes sampling and testing shrimp from every pond on all Texas facilities regularly. In addition, the industry created "Best Management Practices" in the late 1990s and began to use disease-resistant shrimp that significantly reduced the occurrence of disease.
Shrimp farm operators are cooperating fully with authorities to contain the current outbreak. TPWD is monitoring the current situation closely, working with federal authorities and the industry.
"The Department's inspection program is operating just as anticipated and the farms in question are cooperating fully with us," noted Larry McKinney, Ph.D. and coastal fisheries director at TPWD. "Our staff are monitoring the current situation closely and responding in a manner to protect the natural resources of the State of Texas."
Texas shrimp farms are some of the largest in the country, with some five times more production acres than the second ranked state, South Carolina. Shrimp farmers prefer exotic species to natives because they do better in mariculture settings.
Exotic shrimp species can bring exotic diseases with them, but to prevent that from happening Texas shrimp farmers are required to stock their ponds with certified disease-free seed shrimp. Disease outbreaks are a primary concern for farm operators because they have the potential to wipe out an entire crop of shrimp. Previous episodes have caused economic hardship for operators, but no observable impacts were detected in wild stocks.
However, because these shrimp farms are located in coastal areas and there is the potential for disease transmission by birds, escapement, and other vectors there is concern that these diseases might affect native species.
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text:
BWW POLL: Who Do You Think Should Win DANCING WITH THE STARS: ALL-STARS?
DANCING WITH THE STARS first-ever ALL STARS season will conclude next week on ABC with three contestants battling it out to be crowned the Mirror Ball champions. Now it's your turn to vote for who you think most deserves the highly-coveted prize!


text: SCENE + HEARD: Events Block Business Academy by the Beach Planned for January 2014 at Boca Raton Resort & Club By Staff Wednesday, July 17, 2013 12:30 AM BOCA RATON, Fla.— Block Business Group will host Block Business Academy by the Beach at the Boca Raton Resort and Club here, Jan. 24 to 26, 2014. The meeting will offer a multi-faceted program, featuring COPE/ABO approved CE, workshops and a trade show exhibit featuring top industry vendors and Block Practice Builder affiliates. "We invite all eyecare professionals to sunny Florida in January," said Michael Block, president of Block Business Group. "This will be a weekend of learning, networking and purchasing opportunities they won't want to miss." The agenda will include 36 hours of COPE/ABO approved CE to choose from on such key industry topics as medical coding and compliance, pharmacology, buying and selling a practice, contact lenses, EMR and others. There will be also be workshops for practice staff if ECPs want to bring others from their office to attend. The complete trade show floor will feature exhibits from top industry vendors and Block Practice Builder affiliates offering show buying specials. Registration is $49 for Block Business Group members who sign up before Aug. 1. After Aug. 1, it increases to $99. Registration is $249 for non-members but that fee will be reduced to $49 if ECPs join the Block Group and the $200 will be credited to their account after the first month of billing. Included with the registration fee is all the continuing education, a dinner reception Friday night, breakfast, lunch and dinner Saturday, breakfast Sunday, and open access to the trade show and amenities at the world-famous resort. More info is posted at the Block Business Group site or by contacting Block Business Group at (800) 524-1480.


text: Smell the Coffee: Organ donors live on in others By Karin Fuller January 19, 2013 Story Share CHARLESTON, W.Va. -- A little over a year ago, I wrote about a Texas couple who lost their 13-year-old daughter, Taylor, from injuries received in a skiing accident. When told that Taylor wouldn't survive, the family agreed to donate her organs, believing it was something she would've wanted.Taylor's heart went to a 39-year-old Arizona mother of two whose heart had been failing for years, and even though recipients of donated organs are usually kept confidential, publicity following Taylor's death enabled both the donor and recipient families to recognize their connection. They decided to meet.At their meeting, Taylor's mother was able to put her head against the recipient's chest and hear her daughter's heart beating. A part of her daughter was still alive, even if that part was now in someone else.So much time had passed since I'd written that particular column that I'd completely forgotten about it until I received an email from Kelly Paynter, of South Carolina. She was searching online for information on organ donors when she stumbled across my story."It's been almost two years since I lost my mom," Kelly wrote in her email. Her mother, Minnie Paynter, died at age 52 from a pulmonary embolism on March 21, 2011. Many years earlier, mother and daughter had registered together to be organ donors."Mom became a donor the day I received my driver's license at age 16. I was standing in line to get my picture made, filling out the general information, and the guy asked if I wanted to donate my organs. I said yes. Mom stopped me. She was against it. I told her I wanted to live longer than my death, and since cryogenics was out of the picture, I said I'd just find me a new body. Mom liked the idea of living on in other people, so she had her license redone that same day to indicate her intent to be an organ donor as well."Minnie Paynter was one of those admirable single moms. She managed to get off welfare after putting herself through college, while at the same time raising a daughter -- Kelly -- who struggled with asthma and epilepsy. "Mom was one of nine children," Kelly told me. "She was the daughter of a coal miner. They were very poor. My mother was the only one to graduate college, and she graduated with honors."Kelly's pride in her mom was clear. As was how badly she missed her."I need to find these people who received some part of her," wrote Kelly. "I would like to look into my mom's eyes again. Can you please help me find the people she saved? I cannot tell you how painful it felt when I laid my head one last time on her chest, to not hear her heart beating ..." Not long after I began trying to track down the recipients, medical privacy laws brought me to a screeching halt. All I could learn were the steps required for a family member to follow.I wrote Kelly an email, telling her she would need to personally approach the organ transplant coordinator at the hospital where her mother was treated. The person I had talked to recommended she write a letter addressed to the person who received the donation. They said in the letter, she should tell something about the donor and how much it would mean to meet them just once, and then include contact information. The transplant coordinator would then get the letter to the recipients, and it would be up to them whether to make contact.I felt as though like I was letting Kelly down because that's all I could get, but she took it from there. And her results were fast. I expected it would take months, but it didn't.Kelly contacted the hospital where her mom passed away and was given the number for the organ donation center that had received her mom's organs."Within the hour, I was told two families had been given my mother's corneas and that those recipients had already sent a letter requesting contact with the donor's family. They then put me in contact with a mediation center that allowed me to do a three-way call with each recipient. I was able to speak to the people who my mom gave sight to! I was also informed that she had saved a man's life with her bone donation. That family had already requested contact too, so I'm waiting to be put in touch with them through the tissue center. They told me I will be receiving photos of the people my mother helped save. And I was also notified she was given the bronze star because her donations were not rejected by anyone!" Kelly posted on Facebook about what she'd learned about her mom's organs and soon began receiving messages from all over. In the days since, Kelly said her phone and email seem to go off constantly with people wanting to share their donation or recipient story, or simply telling personal stories they had about her mom.Kelly said it's like Christmas is still going on, that each new contact is another gift. That her mom is still around. That she had things yet to do.That she continues to live on in so many people."I would love for you to write about my mom because I truly believe my mom still has work to do," Kelly wrote.So many families whose loved ones donated their organs don't realize it's possible to be in contact with the recipients, and there are so many who don't understand organ donation at all.Reach Karin Fuller via email at firstname.lastname@example.com. Story Share Story Share Trending Now 1 Police seek car driven by woman found dead in Kanawha River 2 Teen pleads guilty to involuntary manslaughter in Oakes Field shooting 3 Facebook founder visits Cabin Creek Health Systems 4 Man allegedly cuts father in Rand over argument about sandwich 5 $115M project for WV Toyota plant to start in 2020 'Mountain Stage' at 30 Previous Story Arborvitae fern a must for the woodland garden Next Story


text:
GED classes to be offered in Gothenburg
The Central Community College Adult Education Program sponsors the classes, which are open to the people who are at least 16 years old, aren't currently enrolled in school and who want to earn a Nebraska high school diploma.
Students will receive help in preparing for the five GED exams in mathematics, reading, science, social studies and writing.
The classes would meet from 6:30 to 8:30 p.m. on Mondays and Tuesdays at the American Lutheran Church, 1512 Ave. G. Students should use the west entrance.
All students must preregister and pay a $20 registration fee. A fee also is charged for each GED test.


text:
Burt's Bees Garden Tomato Toner Reviews
Good tonerThis toner works very well and is priced at a great value.It makes my face feel fresh and clean when I use it. My husband and I both like it. — 6 years, 10 months agoTBjunkie | 692 reviews
Very refreshingThis toner smells like tomato leaves, that reminds you of summer vegetable garden. It has alcohol, but doesn't sting, and is actually perfect amount for my oily complexion. (If you have dry skin, this may be too drying) It tightened my skin and my pores minimized temporarily. Better than most drugstore toners. — 7 years, 10 months agoMakeupGuru | 444 reviews
Good and lasts a long time.I have to say, I really like this toner. A bottle lasts a long time. I have sensitive skin and sometimes it can be a bit too much. The smell is good, but sometimes it can be a bit to strong for those of us sensitive to smell. It does leave your face clean and feeling refreshed. — 4 years, 10 months agoTaylerbootz | 126 reviews
Great and gentle productLove this toner! It feels completely refreshing. I was surprised how much I enjoyed the scent. It really smells like a fresh, straight from the garden tomato. Somehow, it just works. — 6 years, 7 months agoazdrienne | 120 reviews
A good tonerMy wife and I both like this toner. It refreshes my skin well and I like that I can get it at almost any store. — 6 years, 10 months agosteadyeddie925 | 351 reviews
Love Natural Products!I love this! I love Burt's Bees products. They are great for your skin. A bit pricey though. — 9 years, 8 months agomvap47 | 345 reviews
This review is: Helpful | Not helpful | Inappropriate | 0 of 0 people said helpful
doesn't kill your faceA lot of toners I've tried before tend to dry out or irritate my face. This stuff doesn't. I don't need to immediately grab a face lotion right away. It smells like a salad, but it's still a great product. — 9 years, 2 months agoMiss_Vicki | 271 reviews
Good but not tough enoughI bought this with the tomato soap and I actually liked this product much better. i have very sensitive skin so Im trying always to use chemical-free on my skin. I love Burt's Bees because they really "feed" the skin on a deep level instead of just on the surface. I didnt really get a response from my skin as far as less blemishes but I believe I did improve my skin in many other aspects with this. — 5 years, 7 months agoAlisunshine | 146 reviews
This review is: Helpful | Not helpful | Inappropriate | 1 of 2 people said helpful
Very gentleThis is for someone with very sensitive skin. It worked but I like a bit more astringent. — 9 years, 3 months ago23Amber | 146 reviews
Great for normal skin tooFinally a great toner that wont dry out your skin!! It says for oily skin but I have nortmal skin and it doesn't dry me out at all. Feels so refreshing and the smell is delish! GREAT PRODUCT!! — 5 years, 3 months agoKris924 | 5 reviews
This review is: Helpful | Not helpful | Inappropriate | 3 of 5 people said helpful
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BoomBoxes Overview
Great for music on the go or outside these boomboxes are the perfect solution for you. Our great brands Coby and JVC bring your amazing sound in a small bundle that you can use anywhere you want to take it with you. Great for the pool or tailgating you should pick one up today.
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text:
Whatever is to be made of the absurdly hasty firing of coach Mike Brown by the Los Angeles Lakers—the front office is a mess, he was the wrong guy to begin with, injuries prevented him from getting a fair shake, etc.—one thing that is certain is that Phil Jackson can fix this bunch.
That's why Kobe Bryant and Dwight Howard have publicly endorsed his hiring, it's why the fans at Staples Center have been chanting his name, it's why he was the first guy the Lakers called after canning Brown.
It's as simple as this: Phil Jackson gets respect. Mike Brown never really did.
More: Phil almost certain to return | LeBron on Brown | Reaction to firing | Timeline
"It was a little like a ship without a rudder with Mike," said one source close to the situation. "He didn't have the same command that you would want with a team like that. They're veterans and they know when someone is in over their head and it seemed like that was the case with Mike."
Brown's failing, then, was more to do with perception than reality, more about the weight of his voice than about what he was actually saying. Brown is a good coach and knows his Xs and Os, but the Lakers are a team stacked with guys who have been on 35 All-Star teams, guys who have won championships. They don't need Xs and Os from their coach as much as they need a guy they trust.
And going back to the time that Pat Riley left, no coach in Lakerland has earned as much trust as Jackson, who has more rings (11) than fingers.
This has become a pattern. Jackson is like a faded singing star coaxed onstage by the band in a Vegas lounge—"Who me? No, no. … Well, OK, maybe just one song …" Del Harris coached the team in the late 90s and has long been known as one of the league's better tacticians. But he lacked credibility among the players. His teams flamed out in the playoffs, leading to his ouster in 1999, and the arrival of Jackson in L.A. the next year, when the Lakers won the first of three straight championships.
It was much the same in '04-'05, when the Lakers hired Rudy Tomjanovich, who was well down on their original list of candidates. Tomjanovich had championship credentials, but he was overwhelmed by the Lakers job and resigned midway through the season because of health reasons. Jackson was roped out of retirement again, and within three years, L.A. was back in the NBA Finals.
Here we are again, with the Lakers having hit the panic button after five games with their revamped "superteam." No question the players were operating under too much duress to open the year, and some of that should fall to Brown. They were not operating as a unit defensively and, though the impact of the newly installed Princeton offense has been overblown, they were overthinking on offense. Brown didn't have his players in the right frame of mind to open the year, and management obviously felt he might never get them there.
And so all eyes are on Jackson again. Forget the fact that Jackson's triangle offense won't be easy for the new Lakers to learn, and forget the fact that the triangle uses some of the same principles as the Princeton offense. What Jackson has long done best is find a way to prod his teams mentally into reaching their potential, to get the most out of each piece. If Lakers players were lacking confidence in Brown, that will quickly change under Jackson. His voice carried weight that Brown's never could.
Going strictly by the names on the roster, this is the best team in the Western Conference. Put Jackson back at the helm of the Lakers, and they'll start to show it.


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Where to perform the drill: On the practice field
What you will need: Your normal bag of discs and a target (e.g. portable basket, tree, pole, etc.)
Stand 50' away from your target and throw a dozen or so gentle overhand shots (tomahawk or thumber) that land upside down as close to your target as possible. Adjust release angles as needed to get the disc to pan how you want it to. Experiment with various heights and lines.
Move back to 75' and repeat the previous step. Repeat for distances of 100', 125', and 150' (if you have shoulder/arm problems I suggest doing this only to 75', but that range should still be a safe range to throw).
This is a very useful dump shot as well as for getting over small obstacles.


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A BEAUTY spot in Ilminster 'is still a mess' according to residents.
Ross Brion, who lives close to Herne Hill, raised concerns to the town council last month but this week said it remains in a bad way.
He said: "It is now out of control - I have never seen the open spaces in such a mess.
"We should be bringing in outside contractors to sort it out otherwise this is going on and on."
Signs have been placed on the hill telling people there is no cycling allowed and Mr Brion said more rubble had been placed at the hill, due to a future plan to build a lookout, but Mr Brion said he felt the project will never get off the ground.
The council said they have employed a worker through South Somerset District Council who is working around three to five days a week, depending on the work load, to help tackle some of the overgrown areas in the town.
One of the areas, the cemetery, which the News' ran a story on last week, was an issue raised by one member of the public, who described it as 'heartbreaking'.
Cllr Carol Goodall said the weather and a shortage in staff had been a factor in some of the areas becoming overgrown.


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Haryana CM Manohar Lal Khattar in Aap ki Adalat (Full Interview)
Bollywood Actress Kangana Ranaut in Aap ki Adalat (Full Interview)
Bollywood Actor Nawazuddin Siddiqui in Aap Ki Adalat
Bollywood Actor Anil Kapoor in Aap Ki Adalat
Aaj Ki Baat with Rajat Sharma | 18th September, 2017
Aaj Ki Baat with Rajat Sharma | 15th September, 2017
Aaj Ki Baat with Rajat Sharma | 14th September, 2017
Aaj Ki Baat with Rajat Sharma | 13th September, 2017
India vs Australia, 3rd ODI: Australia win the toss at Indore, elect to bat
I'm confident India will whitewash Australia 5-0: Virender Sehwag to India TV
India vs Aus: Virat Kohli misses out on record ton at Eden Gardens
2nd ODI: India win toss, opt to bat vs Australia
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Ajay Devgn's Golmaal Again trailer is already a hit; crosses 20 million views in just 24 hours!
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Amazing day for Newton! Rajkummar Rao's film shows 162% growth on box office, surpassing Bhoomi
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Live Cricket Score, India vs Australia, 3rd ODI: Finch 124 powers Australia to 293/6
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Navratri Special: Want to relive childhood? Top 5 places to watch Ramlila in Delhi
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This Navratri, glam up with different sari drapes like bengali, dhoti or rajrani


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All tickets are sold as General Admission because the inside of the club is one open floor plan. We do not have a separate handicapped section, but there is a handicap ramp. We are happy to make exceptions, so please contact email@example.com in advance to discuss the preferred accommodation.
Thank you to @thetingtings for putting on such an amazing show last night!! photo:@saramarjorie @do512 #thetingtings #emosaustin
Another amazing show tonight! Hope everyone who came out to #lights had a great time! #emosaustin thanks for any other great shot of the night @jenna_million!
Thanks for an amazing #soldout show! #takingbacksunday #emosaustin and thank you to the wonderful @jenna_million for this amazing shot!
@takingbacksunday made damn sure we all had a great time tonight at #emosaustin!! What an amazing show! #takingbacksunday #HappinessIs #soldout
#soldout show tonight! @echosmith, thanks for coming out and rocking it! #echosmith #emosaustin #atx
#motioncitysoundtrack tonight (last night?) was amazing. Thanks to everyone who came out and to #driverfriendly and #teamband. 📷: to the lovely and talented @jenna_million.
Thank you to everyone who came out to Saosin tonight!!! We had an amazing turn out and more importantly an AMAZING performance. #Saosin #emosaustin #atx #concert #AnthonyGreen
Coming to #emosaustin !! @lights Sat 2/21! Tix on sale this Fri at 10 am thru emosaustin.com and c3concerts.com
Tonight! Don't miss @suicidegirls #BlackheartBurlesque at @emosaustin. Doors open at 7:30pm, more info C3Concerts.com
Tonight - Get ready to rock with @BoyceAvenue and @kris_allen at @emosaustin! Doors open at 6pm. More info at C3Concerts.com
TONIGHT - Hope you're ready to jam with Tribal Seeds at Emo's! Doors at 8PM, tix: http://bit.ly/1oMH5bp #reggae #representing
TONIGHT! @savoyband with @brightlights333 at Emo's Austin. Doors open at 9pm, tix available at www.c3concerts.com
Just announced! @mslaurynhill coming to #emosaustin Dec 7th! Tix on sale this Fri at 10 am thru www.c3concerts.com and www.emosaustin.com!
Need some funky Friday plans? The Soul Rebels with Prodigy (of Mobb Deep) and Fat Tony perform here this Friday, 9/19! Doors at 9PM. Tix at c3concerts.com. #soul #funk
The Official 2014 ACL Fest Late Night Shows are here! Check out the full list at c3concerts.com/latenight and subscribe to the e-list by 11:59 PM tonight for access to pre-sales before tickets go on sale to the public! #emosaustin
This FRIDAY AUG 1st @zakkwyldebls and #BlackLabelSociety are coming to @emosaustin w/ @wovenwar & @kyngband! Tix at c3concerts.com
JUST ANNOUNCED! The MMHMM 10th Anniversary Tour w/ @relientk & special guest @blondfire will be at @emosaustin on November 20th! Tix go onsale THIS Friday @ 10am at www.c3concerts.com
JUST ANNOUNCED! @savoyband will be at @emosaustin w/ @brightlights333 on Friday, November 14th! Tix go on sale THIS Friday @ 10am on www.c3concerts.com
NEW SHOW! Andrew McMahon will be at @emosaustin on November 24th! Tix go on sale THIS Friday @ 10am at www.c3concerts.com
JUST ANNOUNCED! @officialsomo at @emosaustin November 25th! Tix go on sale THIS Friday @ 12pm at www.c3concerts.com
Epic show tonight. Chevelle is absolutely rocking. Thanks for the shot, @xelijah. #emosaustin #atx #chevelle
Just announced! 10.31 @therevivalists at @emosaustin with @thelondonsouls & @monophonicsfunk - Tickets on-sale Fri 7/18 10 AM at c3concerts.com


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John Tavares, one of the NHL's brightest young stars, is having a strong season with 13 goals and 12 assists.
On Sunday, the young Islanders forward broke out a nifty move to help New York top the Ottawa Senators in a shootout for a 3-2 win.
Tavares broke out "The Forsberg Move" to beat Senators goalie Robin Lehner and seal the victory. The move was made famous by retired NHL star Peter Forsberg. Check it out for yourself.


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Karen Tracey, Creative Director at The Image Shoppe
When you think of commercial real estate, the words passionate or innovative aren't usually top of mind. Well, X Ventures just may change your perspective. Chip Bowling came to The Image Shoppe with an idea and from the bottom up, we did our research, examining what the industry does, then strategizing how to do it better.
We channeled Chip's energy into every minute detail of brand identity—naming, positioning, logo design, web development, etc.—establishing X Ventures in the market as the company pushing standards on an otherwise stale industry. We were able to work closely with Chip to transform a personality into an unparalleled, high-quality experience that radiates passion. Now he has become the poster client for how to live, breathe and radiate a brand.
chip Bowling, president x ventures


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1987 Pace-Arrow Prices, Values and Specs
Select a 1987 Pace-Arrow Series
Pace-Arrow Note
MOTORHOMES - Did not manufacture from 2011-2015
(2017 - 1969)
Once a popular line-up of Class A motorhomes, the Pace-Arrow name appeared in the 1960s. Pace-Arrow was acquired by Fleetwood during the 1970s and continued for years as a premier choice for family cross-country adventure for diesel-powered motorhomes. Ranging up to 38 feet in length, the Pace-Arrow brand of motorhomes were constructed until the 2010 model year.


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Astros agree with pair of draftees, close with another
MINNEAPOLIS -- The Astros have agreed to terms with eighth-round pick Bobby Boyd, a speedy center fielder from West Virginia University, and 10th-round pick Jay Gause, a right-handed pitcher from Faulkner University in Alabama.
Meanwhile, the Astros and sixth-round pick Brock Dykxhoorn, a right-handed pitcher from Central Arizona College, have agreed to a signing bonus and should have a contract done soon after working through the final details.
Boyd told MLB.com he expected to sign his contract within the next day or so and report to Tri-City in the New York-Penn League.
"I'm really excited about it," Boyd said. "It's definitely a dream come true. I really didn't expect this day to come. It was amazing."
The pick, which was No. 226 overall, has an assigned slot value of $162,800.
Boyd, a 5-foot-9, 180-pounder, was a junior for the Mountaineers this year and led the team with a batting average of .356. He also tallied 24 RBIs and 18 stolen bases. He garnered All-Big 12 Honorable Mention honors during his sophomore season in which he hit .314 and stole 17 bases.
Gause told MLB.com he planned to sign his deal and will be in the rotation at short-season Tri-City.
"I'm excited, man," Gause said. "I plan on being in the rotation sometime in the next week or so. I've been waiting on this opportunity for two or three years now. I got drafted out of high school (25th round by Indians in 2010) and turned it down and went to college. So I've been waiting for this."
Gause, 6-foot-5, 250 pounds, is coming off a season in which he threw 58 innings and had a 2.17 ERA, along with 83 strikeouts and 24 walks. He is from Shallotte, N.C., and previously attended Walters State Community College.
The pick, No. 286 overall, comes with an assigned slot value of $142,100.
Dykxhoorn is a 6-foot-8, 240-pound pitcher out of Central Arizona College, where he posted an ERA of 2.77 in 78 innings. Dykxhoorn struck out 114 while walking 27.
Dykxhoorn, 19, was drafted in the 20th round out of high school by Cincinnati in 2012 and was a member of Team Canada's junior national team. He pitched in 10 games his freshman season at West Virginia, posting a 3.15 ERA and a 2-1 record. He struck out 20 and walked 11 before moving to Central Arizona College.
"I have basically agreed to a signing bonus -- and it's just the education package and stuff, just minor stuff like that [which needs to be ironed out]," Dykxhoorn told MLB.com. "It's definitely exciting and a bit of a relief, too. I knew what I wanted going in, and the Astros were able to meet it. It was a pretty easy decision for me."
The pick, No. 166 overall, comes with an assigned slot value of $277,400.
Because he's a native of Ontario, Canada, Dykxhoorn said he would need to acquire a work visa before he could report to a Minor League club.
Brian McTaggart is reporter for MLB.com and writes an MLBlog, Tag's Lines. Follow @brianmctaggart on Twitter. This story was not subject to the approval of Major League Baseball or its clubs.


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LOUISVILLE – No matter when it is played or where it is contested, a Bullitt East-North Bullitt hoops contest is going to be a war.
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The Ricky Gervais Show
TV14 Duration 0:31 :
An animated version of the record-breaking podcast series.
Subscribe now to watch blockbuster movies and acclaimed HBO Films as they air or anytime you like on HBO GO.
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Designed for the hardest conditions, to reduce the strain and increase the sheer enjoyment of helming.
The Asymmetric grip improves helming performance in three ways:
• All the features of the Asymmetric but with a slimmer grip.
• The compact solution for the smaller cockpit and ideal for hiking and fast tacking.
• Push-button adjustment with Torlon™ ball locking mechanism.
• Strongly engineered stainless steel swivel joint for precise control.
• Removable fast pin for easy stowage.
• Integral shock absorber.
• Weight: 510g (17.0oz)
Part Number: EJ/1200C


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I figured I might be doing quite a few of these because the first one went ok, so this is the thread where I'll post my dyes
To recap. Here's the first. Ugly, but functional.
This one is number 2. It was far more complicated to cut, but I used a homemade lightbox which made it way easier than "The Jish". The image is of Matrim Cauthon. For those who haven't read the 'Wheel of Time' series this is a character who is unnaturally lucky which is good because this is my lucky driver


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Start a New, Fulfilling Career Today
At Herzing University, a college education is within your reach. Whether you are a recent high school grad, an international student, a transfer student, or a working adult, we'll help you find the right undergraduate program for your educational and career goals.
We offer a personal approach to college admissions. Our admissions advisors are with you every step of the way to answer questions, provide guidance, and help you realize your dream of a college degree.
Let's Get Started
We've made our undergraduate admissions process simple and straightforward. Here is what you need to know to get started.
Step 1: Meet with an Admissions Advisor
Schedule an interview with one of our admissions advisors. You'll learn important information about our programs, scheduling, start dates, enrollment requirements, student services, and employment opportunities for graduates. We will also review your prior education, explore our program options with you, and answer any questions you have regarding your education.
For those looking to attend one of our local campuses, we will also take you on a tour to familiarize you with the campus and to provide you with a better understanding of what you can expect from your educational experience.
Step 2: Apply
Submit your application online or in person at one of our campus locations. We accept applications for admission on a continuous basis. Application requirements vary by location or program. Provide your official high school transcript, GED, or HSED. If you don't have a copy, you have the option of completing a High School Transcript Request Form to have Herzing request the transcript on your behalf. Upon acceptance to your program, you will be automatically registered into the appropriate classes needed for your program of study.
Follow the links within to learn more about additional admissions requirements or information for military students and veterans or if you're transferring from another institution.
Step 3: Complete Your Enrollment
In addition to working with you to complete your admission requirements, we will continue to work with you to complete your enrollment. This includes putting together a comprehensive funding plan. If you are planning on using the Federal Financial Aid program to help fund your education, you can complete the first step in that process now by completing your FAFSA (Free Application for Federal Student Aid). Additionally, you can pay the $50 enrollment fee. Please note that the enrollment fee for Akron and Toledo is $25.
Step 4: Start Classes
This is why you came here and when the fun really begins! We have classes starting every month. We are ready to work with you through all of the required steps to keep you moving forward toward your academic and career goals. (Note: some of our selective programs do not start every month, but your advisor will review this with you when you meet). We will continue to be with you every step of the way through your program of study to assure that your experience with Herzing is second to none.


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ORLANDO, Fla. - Most of the employees at Merita Bread Bakery in downtown Orlando are out of a job on Friday after Hostess Brands -- the maker of Twinkies, Drake's Devil Dogs and Wonder Bread -- announced Friday that it is asking to close its operations.
A handful of the Orlando factory's almost 200 workers showed up to work Friday morning to find out Merita Factory won't be functioning anymore. Hostess is asking a federal bankruptcy court for permission to close its operations, blaming a strike by bakers protesting a new contract imposed on them.
Some workers say they blame the union for their job loss, saying the picketlines are the reason he's out of the job.
"You just ruined everybody's holidays... " said Johnny Santiel. "It's a sad thing."
Even retired workers came out on Friday to show support for their coworkers.
"That hurts, I've got a lot of friends here that worked here for years and retired and I'd hate to see anything happen to the bakery," said Blaine Hensley, a retired Merita worker.
Hostess announced it would lay off 18,500 employees across the country. Local 6 spoke to the union outside of the Merita Bakery, who said the majority of the workers at the Orlando plant voted to go on strike.
Residents tell Local 6 they are sad to see the iconic bakery go.
"This is an Orlando icon Merita bread it's been here since the 20s," said Lee Davis, a retired Merita worker. "It's a sad day because I started here when I was 17 years old going to Boone High School, working at the old bakery after school."
Watch Local 6 for more on this story.
Copyright 2012 by ClickOrlando.com. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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Jeter passes Aparicio for games played at shortstop
CHICAGO -- Derek Jeter logged a notable career milestone on Friday when he appeared in his 2,583rd career game at shortstop, tying Hall of Famer and former White Sox standout Luis Aparicio for second place on baseball's all-time list. Jeter played in his 2,584th game at shortstop Saturday to pass Aparicio. Jeter also became the American League leader in games played at the position.
Aparicio and Jeter trail only Omar Vizquel (2,709) on the all-time list. The Yankees only have 115 regular-season games remaining in what Jeter has said will be his final season, so Jeter will finish his career second on the list behind Vizquel, who played the majority of his career in the AL but also spent some time in the National League.
"Aparicio, everyone knows how great he is. I guess it's ironic that we're here," Jeter said. "It's hard to believe when you think about the history of the game that there's only one guy that has played more games. It's something I'm proud of. I take pride in doing my job and being able to play every day. To have your name in the company of someone like him is pretty special."
Jeter, who has only played shortstop during his big league career, has made the most appearances at any single position in baseball history without having played another position.
"It's amazing what he's done in his career," Yankees manager Joe Girardi said. "The consistency, still being able to play shortstop; it's pretty amazing."
Girardi said that Jeter's professional attitude is responsible for his longevity.
"His effort in the winters and during the year, taking care of his body, taking care of himself at night," Girardi said. "You don't read about Derek at places at 2 and 3 [in the morning]; that's just not who he is. He understands that he has a responsibility to the team and he takes care of it."
With a run scored in Friday's 6-5 loss to the White Sox, Jeter also has 1,889 career runs, passing Lou Gehrig for second place on the Yankees' all-time list (Babe Ruth is first with 1,958). Jeter ranks 10th on Major League Baseball's all-time list (Alex Rodriguez is ninth with 1,919).
Bryan Hoch is a reporter for MLB.com. Follow him on Twitter @bryanhoch and read his MLBlog, Bombers Beat. This story was not subject to the approval of Major League Baseball or its clubs.


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Topic: Yay, Social Security Disability comes through!
Finally, something good is happening for me! My social security disability was approved today! It's weird though, I'm sad I'm eligible for it but happy it's available. It is my money after all.
I did a phone interview and was lucky enough to have a wonderful lady doing the interview who was very sympathetic and willing to go the extra mile for me. We were able to get the medical release form to her the same day, so it went through really really fast. Thank God for small favors!


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On Campus
Kuwaiti Minister of Education Headlines International Business Event
When Dr. Moudi Al-Homoud, the Kuwaiti Minister of Education, spoke at Kogod on Nov. 7, her message was clear: In Kuwait, "unemployment has a feminine face."
She was referring especially to the public sector in Kuwait, where only 4 percent of the workforce is female. "Scarcity of relevant role models, lack of culture fit, and existing business politics and hierarchies are among the barriers to female leader advancements."
The fifth in a line of speaking engagements organized by Ghiyath Nakshbendi, executive-in-residence in International Business, the event's focus was "Women in Business: Kuwait Experience." Dr. Al-Homoud, who is also minister of higher education and chancellor of Kuwait University, was the feature speaker.
Dr. Al-Homoud spoke on the accomplishments of Kuwaiti women in areas of education, politics and economics, but also highlighted the challenges they face in gaining equal employment opportunities to their male counterparts.
She also highlighted the discrepancy between the number of young, educated women in Kuwait, and the number of women in the workforce. She is working through her roles to change the status quo and bring about awareness to the benefits of having skilled women in the public and private sectors of Kuwait.


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NetWellness is a global, community service providing quality, unbiased health information from our partner university faculty. NetWellness is commercial-free and does not accept advertising.
Saturday, September 23, 2017
Elective below the knee amputation
I had an accident when I was 18. I am 39 now. I have constant pain in my knee and ankle. The only options I am given right now are to have complete recontructive surgery on my ankle and a complet knee replacement. My quetion is this... I would like to have my leg amputated because I think in the long run I would be better off considering my age. With just the reconstructive and replacement surgey I am guessing that i will end up having worse artritis than I have now, and will have to keep having knee surgerys every 10 years. And the biggest thing in my mind is I could probably run with my 6 year old son if I have a prostheses. I am a healthy, well, fit man, except my leg of course, so I really think amputation is the way to go. What do you think?
If you were to proceed with an above-knee amputation, you may or may not become capable of running with a prosthesis (assuming there are no complications from an amputation surgery, your postoperative recovery and rehabilitation proceed smoothly, and your residual limb becomes capable of tolerating forces such as those associated with running), depending on the choice of prosthetic componentry (FYI, the newer, sophisticated microprocessor-controlled knee units are not designed for running), your overall physical condition, the condition of your opposite leg and lower back, and your body weight, among other considerations.
Prior to undergoing such surgical interventions as ankle reconstruction or knee replacement, nonsurgical treatment options should ideally have been exhausted and without sufficient benefit. You may consider verifying this is, indeed, the case by getting additional opinions, if you've not already done so, from another orthopedist (who performs amputation surgery as part of their practice), but also from a physical medicine and rehabilitation physician, as well as a prosthetist, and ideally, also, one or more active above-knee amputees around your age. A team approach to assist with making such a serious and irreversible decision is always preferable.
Brian L Bowyer, MD
Clinical Associate Professor
Physical Medicine & Rehabilitation
College of Medicine
The Ohio State University


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Arts & Culture
In Which Philip Roth Announces His Retirement (in English)By Nelly Kaprielian
Last month our friends at the French cultural magazine Les Inrockuptibles reported that Philip Roth has called it a day, and the world took notice. Here is the full interview with Nelly Kaprielian, in English. —Lorin Stein
Out of all your novels, Nemesis seems to be the one where you lay out most clearly your own vision of existence.
That's true. I think everything in life is a matter of luck. I don't believe in psychoanalysis, or in a subconscious that guides our choices. All we have is the good luck or the bad luck to meet certain people who will be either good or bad for us. My first wife, for example, turned out to be a criminal—she was always stealing, lying, and so forth—and it's not as if I chose her for that reason. I hate criminals. But there you are, I had the bad luck to marry a bad person. Psychoanalysts will tell you that I chose her unconsciously—I don't believe in that, though in a certain way this isn't far from my own view, which is that, in the face of life, we are innocents. There is a certain innocence in each of us in the way we deal with our lives.
Nemesis belongs to a group of four novels entitled "Nemeses" (including Everyman, Indignation, and The Humbling). How are they connected?
Each one deals with the subject of death from a different point of view. In each of these books, the protagonist has to face his "nemesis," a word one hears a lot in the United States, and which could be defined as doom, or misfortune, a force that he can't overcome and that chooses him as its victim. Read More


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Today: Tech-focused Nasdaq composite index is latest to hit a milestone number, closing higher than 4,000 for the first time since the dot-com boom collapsed. Also: Hewlett-Packard (HPQ) earnings arrive after Workday and Palo Alto Networks surge higher on their reports.
As Twitter's explosive Wall Street debut and the performance of momentum stocks such as Tesla spur technology-stock bubble talk around Silicon Valley, the Nasdaq composite index Tuesday reached a milestone unseen since the original tech bubble popped at the beginning of the millennium.
The tech-heavy stock index closed higher than 4,000 on Tuesday, the first time it has reached that high since 2000, when years' worth of exuberance for Silicon Valley technology companies suddenly collapsed.
The index first passed that mark just as Y2K concerns had engineers furiously working overtime: Dec. 29, 1999. However, those eager to compare the current explosion in valuations for technology companies are going to find that the growth this time around is much different, and certainly not just focused on tech: The blue-chip Dow Jones industrial average hit a record round number last week, and the Standard & Poor's 500 followed a day later.
When the Nasdaq reached the 4,000 mark at the end of 1999, it was completing a year that saw the index nearly double, growing 85.6 percent. While the Nasdaq index has had a solid year in 2013, it can't even sniff those results: After Tuesday's 0.6 percent gain to 4017.75, it has increased 33 percent so far this year.
What happened next more than a decade ago seems even more out of reach in today's markets: After reaching 4,000 at the end of 1999, the Nasdaq took less than three months to cross 5,000, gaining 25 percent in fewer than 50 sessions and closing at an all-time high of 5,048.62 on March 10, 2000.
"The euphoria just isn't there on a mass scale today." Drew Nordlicht, managing director at wealth-management company HighTower, told USA Today after the Nasdaq crossed 4,000 in intraday trading Monday.
The difference shows in investors' ability to differentiate between a good tech investment and a questionable one. At the end of the last millennium, technology companies with questionable business models and sketchy prospects were arriving on Wall Street to huge valuations and fanfare pretty much across the board. Now, while Twitter and a host of enterprise-software companies have found resounding demand for early shares, Silicon Valley companies such as Violin and Chegg have experienced a far different welcome to Wall Street.
"This time, the market is differentiating between business models that are working and those that are not," Dan Veru, chief investment officer at Palisade Capital Group, told USA Today.
Despite the differences, this year's gains can rattle nerves in Silicon Valley.
"Everyone feels like the valley has been in a boom cycle for quite some time. That makes people nervous," Yelp CEO Jeremy Stoppelman told The New York Times for an article titled, "In Silicon Valley, Partying Like It's 1999 Again."
Beyond that Times headline, however, few feel that a bubble similar to the late '90s has officially formed around the valley, with the lessons of that time still fresh in many minds.
"It's taken 13 years to get back," Jack Ablin of BMO Private Bank told USA Today. "It just shows the magnitude of that bubble we expanded back in 1999 and 2000."
SV150 market report: Hewlett-Packard gains after earnings report
Aside from the Nasdaq's rise, Silicon Valley's pre-Thanksgiving news has focused on earnings reports, with Hewlett-Packard releasing the biggest of the week Tuesday afternoon and enjoying after-hours gains on Wall Street.
HP's revenues continued to suffer year-over-year declines in the most recent quarter, but the Palo Alto tech giant's sales easily topped analysts' projections and the announcement of a fresh dividend cheered investors to drive up the company's stock price. Hewlett-Packard reported a $1.4 billion profit, or 73 cents a share, on revenues of $29.1 billion, a decline from $30 billion last year but well above the average analyst forecast of $27.9 billion, according to a Thomson Reuters survey. "There is some hope given that the company was able to jump over what was admittedly a pretty low hurdle," Edward Jones analyst Bill Kreher told Reuters. After shares closed with a 0.9 percent decline at $25.09, they shot up to near $27 in after-hours trading.
TiVo and Infoblox joined HP in announcing quarterly results Tuesday, but reactions to the two SV150 companies' reports was quite different. San Jose-based TiVo earned $12.5 million, or 10 cents a share, on revenues of $117.3 million, easily defeating analysts' average forecast; The company's stock, which ended Tuesday's session with a two-cent gain at $13.24, gained as much as 3 percent in late trading. Santa Clara's Infoblox was not as fortunate, with shares falling more than 20 percent after a report that met analyst expectations for the previous quarter but included a forecast that was much weaker than expected.
Monday's earnings reports led to big gains Tuesday for Workday and Palo Alto Networks. Workday shot 12.7 percent higher to $82.60 after the Pleasanton cloud-software company announced that revenues increased 76 percent in the quarter that marked the anniversary of its initial public offering. Palo Alto Networks, which launched its IPO just three months ahead of Workday, gained 7.4 percent to $49.49 after showing Wall Street its own strong revenue gains.
Apple (AAPL) and Google (GOOG) were two of the most important factors in Tuesday's positive push by the Nasdaq and SV150. Apple gained 1.8 percent to $533.40 a day after confirming the acquisition of PrimeSense, as the Cupertino company won a patent battle with a man who claims to have invented the smartphone and received a patent for post-picture focusing technology similar to the Lytro. Google advanced 1.2 percent to $1,058.41 after announcing that its low-priced Motorola smartphone, the Moto G, would be available in the United States well before the expected launch date. Pandora also gained Tuesday, increasing 3 percent to $28.79 as its quest for federal legislation to reduce the rates webcasters like the Oakland company pay to artists seemed to come to an end, and Facebook moved 2.4 percent higher to $45.89.
Intel (INTC) headed the other way Tuesday, losing 0.4 percent to $23.65 after Bloomberg News reported that the Santa Clara chipmaker was seeking $500 million for its struggling TV unit. eBay (EBAY) declined 0.6 percent to $48.76 as investors seem inclined to believe Amazon will have a stronger holiday shopping season, and Tesla Motors (TSLA) fell 0.3 percent to $120.50.
Up: Workday, Palo Alto Networks, Yelp, SunPower (SPWRA), Pandora, LinkedIn, Splunk, Twitter, Facebook, Apple, SanDisk, AMD, Applied Materials, Netflix (NFLX), Google, SolarCity, Yahoo (YHOO), Nvidia, VMware
Down: Symantec, Juniper, Electronic Arts (ERTS), HP, Zynga, Salesforce, eBay, Adobe (ADBE), Intel, Gilead, Cisco (CSCO), Tesla
The SV150 index of Silicon Valley's largest tech companies: Up 11.84, or 0.84 percent, to 1,416.49
The tech-heavy Nasdaq composite index: Up 23.18, or 0.58 percent, to 4,017.75
The blue chip Dow Jones industrial average: Up 0.26 to 16,072.8
And the widely watched Standard & Poor's 500 index: Up 0.27, or 0.01 percent, to 1,802.75
Check in weekday afternoons for the 60-Second Business Break, a summary of news from Mercury News staff writers, The Associated Press, Bloomberg News and other wire services. Contact Jeremy C. Owens at 408-920-5876; follow him at Twitter.com/jowens510.


text: I finally got out today and taped some throws. I have been playing for about a year now and thanks for this site I can get my wizard around 250 ft, roc between 275-300 ft, and my drives around 300-350 ft. Also a thanks to Aaron for the Virtual Dub reference. That program is great in breaking down your throw. Anyways let me here your suggestions. I can see that my weight isn't as forward as I thought. Also I really wasn't feeling it today. I don't know if I was trying to hard or what but hopefully your suggestions will let me know why I wasn't feeling it. I have one video that contains three throws at normal speed and then the same three throws at slow speed. Thanks in advance.


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A ruling issued by a federal appeals court Tuesday has called into question whether West Virginia will be able to offer health insurance subsidies through the Affordable Care Act.
In its decision, the U.S. Court of Appeals for the District of Columbia Circuit ruled that states that partnered with the federal government to create an ACA insurance exchange were not eligible to offer consumer subsidies, finding that the law as written allows subsidies only for exchanges "established by the state." West Virginia, which operates a partnership marketplace that gives some responsibility to the federal government, is one of 36 states with an exchange that is fully or partially federally run.
In a contradictory ruling also issued Tuesday, the Fourth Circuit Court of Appeals, which includes Maryland, North Carolina, Virginia and West Virginia, upheld the portion of the law that grants subsidies. The Obama administration has already said it will appeal the D.C. court's ruling.
"It is our understanding the D.C. Circuit and the Fourth Circuit have reached conflicting conclusions with respect to certain tax issues raised by the Affordable Care Act," Chris Stadelman, communications director for Gov. Earl Ray Tomblin, wrote in an email. "We continue to review today's decisions and will monitor future court action related to the Affordable Care Act."
Split appeals court decisions are a classic route to the Supreme Court. But in this situation, it's far from clear what will happen because the administration still has a legal card to play.
Since the Washington case was decided by a three-judge panel, the administration will ask the full 11-member appeals court to hear the case. The full U.S. Court of Appeals for the District of Columbia Circuit has seven judges appointed by Democratic presidents, including four by Obama.
If the full court comes out in favor of the administration, the prospect of Supreme Court involvement would be greatly diminished. On the other hand, if the full Washington court stays out of it or, after a hearing, essentially leaves the panel's decision in place, then the Supreme Court would almost certainly weigh in.
David Klemencic, the owner of Ellenboro Floors in Ellenboro, West Virginia, was one of the plaintiffs in the D.C. Circuit case. Klemencic is the sole proprietor of his business and has no employees, and according to the suit, makes roughly $20,000 per year. Without the subsidies offered by the federal government, Klemencic would be exempt from the ACA's individual mandate, as his health-care premiums would exceed 8 percent of his annual income.
"It was going to put me out of business," he said. "It would have forced me to buy health insurance, and my store is in Ellenboro, where there are only 385 people — only enough of a customer base to barely make a living. If I had been forced to start paying for health insurance, there's no way I could turn a profit for such a small shop."
Perry Bryant, executive director of West Virginians for Affordable Health Care, said the D.C. ruling, if upheld on appeal, could have sweeping implications for the law.
"If you were to take away the subsidies, the premiums would be unaffordable for most people," Bryant said. "Then the question becomes, if the premiums are unaffordable, can you really impose the individual mandate? And if you can't impose that individual responsibility, can you require insurance companies to cover pre-existing conditions if not everyone is in the system?"
Individuals who earned up to 400 percent of the federal poverty level are eligible for subsidies under the ACA. That covers 86 percent of West Virginians who have applied for coverage through the ACA marketplace, said Renate Pore, the health policy director for WVAHC.
"More West Virginians would qualify for assistance than any other state in the country, so we will clearly lose an opportunity — not so much our government, but the citizens of the state will lose out on health-care security they deserve," Bryant said.
The state also surged in its Medicaid enrollment — nearly 154,000 state residents had enrolled in Medicaid or the Children's Health Insurance Program between Oct. 1 and April 30. Another nearly 25,000 had enrolled through the insurance marketplace with private insurance plans; the two combined account for roughly one-tenth of the state's total population.
The average value of the subsidies equals $4,000 per person per year, according to Pore — a total subsidy of around $100 million for the 25,000 who enrolled last year. For those Americans who enrolled in insurance through the ACA last year, the average monthly premium was $86 — 76 percent less than the full premium, according to The Wall Street Journal, which cited information from the U.S. Department of Health and Human Services.
"Some of that money goes to insurance industry profits, some of it goes to all of the transaction costs, advertising; some of it will go to the health-care system — it will reduce the cost of uncompensated care," Pore said. "It has a huge ripple effect."
Justice Department spokeswoman Emily Pierce said the Washington court got it wrong.
"We believe that this decision is incorrect, inconsistent with congressional intent … and at odds with the goal of the law: to make health care affordable no matter where people live," Pierce said in a statement.
In Richmond, the three-judge 4th U.S. Circuit Court of Appeals panel was unanimous in its decision upholding the law's financing. That court said the IRS did a reasonable job of interpreting legal language that is "ambiguous and subject to multiple interpretations."
In a concurring opinion, Judge Andre Davis used pizza as an analogy. He wondered what would happen if he were to ask a friend for ham and pepperoni pizza from Pizza Hut, adding that Domino's would be fine as well. If the friend came back with Domino's, that would fulfill his request, he wrote.
The seemingly arcane issue could be crucial to the success of the health law because most states have been unable or unwilling to set up their own exchanges. The inaction stems in many instances from opposition by Republican governors to the Affordable Care Act.
It all revolves around four words in the 900-page law, which says tax credits to help pay premiums are available to people who enroll through an exchange "established by the state."
The challengers to the law say a literal reading of that language invalidates the IRS subsidy to people in the federal exchanges.
The Obama administration and congressional and state legislative supporters of the Affordable Care Act say the challengers are failing to consider the words of the statute in its entirety.
The Supreme Court has considered several challenges to the health-care law, most recently ruling that some private companies don't have to cover birth control if it offends religious scruples. The biggest ruling came in 2012, when a divided court let stand the law's core requirement that most Americans carry health insurance or face fines.
The Associated Press contributed to this story.
Reach Lydia Nuzum at firstname.lastname@example.com, 304-348-5189 or follow @lydianuzum on Twitter.
CORRECTION: An earlier version of this story misstated the number of West Virginians eligible for health care subsidies through the ACA marketplace.


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Indianapolis -- Finish Line Inc. reported Friday a loss of $107,000 for the quarter ended Dec. 1, compared with a profit of $5.55 million in the year-ago period. The unexpected swing, said the company, was due in part to a lukewarm response to Finish Line's new online store.
Sales in the quarter climbed 5.2% to $296.6 million, missing Wall Street's expected $296 million in revenue, and same-store sales rose 3.6%.
"The third quarter was clearly more challenging than we anticipated," said CEO Glenn Lyon. "Sales came in below plan due primarily to a shift within athletic footwear trends and a less than favorable consumer response to the new ecommerce site we launched in mid November."
The company, said Lyon, has reverted back to its previous e-commerce site. It has lowered its full-year earnings estimate.


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Wisconsin moved up to No. 3 in AP Poll
The Reuters Sports Xchange
Arizona and Syracuse hung on to the top two spots in the Associated Press top 25 for the sixth straight week, but six new teams entered the poll, which was released Monday.
Top-ranked Arizona (17-0) received 61 first-place votes while No. 2 Syracuse (16-0) picked up the remaining four votes.
Several changes to the poll occurred after 11 ranked teams lost at least one game in the past week.
Wisconsin moved into the top three, Michigan State was fourth and Wichita State rounded out the top five. Villanova, Florida, Iowa State, Oklahoma State and San Diego State made up the rest of the top 10. Ohio State dropped from third to No. 11.
Duke, which dropped out of the top 10 for the first time since 2007 last week, fell further this week from 16th to No. 23.
No. 19 Cincinnati, No. 20 Creighton, No. 22 Pittsburgh, No. 24 Saint Louis, and Oklahoma and UCLA, which tied for 25th, moved into the rankings. They replaced Oregon, Missouri, Gonzaga, Illinois and Kansas State.


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Posted 6 years ago
(1 item)
This is a very "Rare Brass Chinese Winepot", which, depicts the old chinese theme "Three Visit To The Thatched Hut", reading the characters from top to bottom. This piece is from the years of the Eastern Han Dynasty, the characters located on the bottom of the piece
is "old chinese", which, is stated to be from the B.C. ERA. The width of the pot is (3 3/16 in. - which is roughly 8.5cm - from the spout to the handle 5 5 /16in which is roughly 13.5 cm. The Height 3 5/16 in. which is roughly 9cm. I purchased this pot in a flea market in 1995, the piece is in excellent condition and well taken care of.


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A Longitudinal Study of Amyotrophic Lateral Sclerosis (ALS) Biomarkers
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
|Amyotrophic Lateral Sclerosis Nervous System Diseases Sclerosis Motor Neuron Disease Spinal Cord Diseases Central Nervous System Diseases Neurodegenerative Diseases Neuromuscular Diseases ALS
|Study Type:
|Study Design:
|Observational Model: Case-Only
Time Perspective: Prospective
|Official Title:
|A Multicenter Study for the Discovery and Validation of ALS Biomarkers
- ALS Functional Rating Scale [ Time Frame: Approximately every 4 months ]The ALSFRS-R is a quickly administered (5 min) ordinal rating scale used to determine a subject's assessment of their capability and independence in 12 functional activities. There are 12 questions, graded by the subject 0-4 (4 is normal). Score of 0 (worst) to 48 (best). Reflects speech and swallowing, fine motor skills, large motor skills, and breathing.
- Vital Capacity (VC) [ Time Frame: Approximately every 4 months ]The vital capacity (VC) (percent of predicted normal) was determined using the slow VC method. Vital Capacity is the maximum amount of air a person can expel from the lungs after a maximum inhalation. A subject's VC depends on their age, sex and height. The value is recorded as a percent of predicted normal.
- Hand Held Dynamometry (HHD) [ Time Frame: Approximately every 4 months ]Hand Held Dynamometry (HHD) will be used as a quantitative measure of muscle strength for this study. Six proximal muscle groups will be examined bilaterally in both upper and lower extremities (shoulder flexion, elbow flexion, elbow extension, hip flexion, knee flexion, and knee extension), all of which have been validated against maximum voluntary isometric contraction (MVIC) testing.
- Ashworth Spasticity Scale [ Time Frame: Approximately every 4 months ]This is a standard measure for spasticity, has been used in a previous ALS clinical trials, and is applied in the current trial to evaluate the progression of spasticity due to upper motor neuron dysfunction in ALS.
- Fronto-Temporal Dementia (FTD) Assessment [ Time Frame: Approximately every 4 months ]The FTD Screening Assessment is a quickly administered scale used to evaluate memory, executive functions, and language. It is aimed at determining the presence of subtle dysfunction of these domains of cognition and behavior that may portend the onset of FTD or FTD-like symptoms.
- ALS Cognitive Behavioral Screen (ALS CBS) [ Time Frame: Approximately every 4 months ]
The ALS Cognitive Behavioral Screen (ALS-CBS™) is a short measure of cognition and behavior in patients with Amyotrophic Lateral Sclerosis (ALS). The cognitive section includes commonly used elements of standard testing batteries, consisting of 8 tasks, with a possible total score of 20. It can be administered by a physician or other clinical care staff and takes approximately 5 minutes to complete.
The behavioral section (ALS Caregiver Behavioral Questionnaire) is composed of questions sensitive to organic brain changes. It consists of a set of questions that compare changes in personality and behavior since the onset of ALS, as well as yes/no questions about mood, pseudobulbar affect, and fatigue. It is completed by a caregiver, family member or other informant during the same time that the patient completes the cognitive portion. The questionnaire typically takes about 2 minutes to complete.
Biospecimen Retention: Samples With DNA
|Study Start Date:
|November 2011
|Study Completion Date:
|December 31, 2016
|Primary Completion Date:
|December 31, 2016 (Final data collection date for primary outcome measure)
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
|Sampling Method:
|Non-Probability Sample
Inclusion Criteria:
- Age 18 or older
- Diagnosis of suspected, possible, probable or definite ALS according to El Escorial Criteria
- Vital capacity (VC) at least 50 percent predicted
- Able to undergo multiple lumbar punctures
Exclusion Criteria:
- Abnormal CSF pressure or intracranial/intraspinal tumors
- Use of anticoagulant medication that cannot be safely withheld
Bleeding disorders
- This is a partial listing.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01495390
|United States, Arizona
|Barrow Neurological Institute
|Phoenix, Arizona, United States, 85013
|United States, Florida
|Mayo Clinic Jacksonville
|Jacksonville, Florida, United States, 32224
|United States, Georgia
|Emory University
|Atlanta, Georgia, United States, 30322
|United States, Massachusetts
|Massachusetts General Hospital
|Boston, Massachusetts, United States, 02114
|University of Massachusetts Medical Center
|Worcester, Massachusetts, United States, 01655
|United States, Pennsylvania
|University of Pittsburgh
|Pittsburgh, Pennsylvania, United States, 15213
|Principal Investigator:
|James D. Berry, MD, MPH
|Massachusetts General Hospital
Additional Information:
|Responsible Party:
|James D. Berry MD, Principal Investigator, Massachusetts General Hospital
|ClinicalTrials.gov Identifier:
|NCT01495390 History of Changes
|Other Study ID Numbers:
|Study First Received:
|December 16, 2011
|Last Updated:
|May 24, 2017
|Individual Participant Data (IPD) Sharing Statement:
|Plan to Share IPD:
Keywords provided by James D. Berry MD, Massachusetts General Hospital:
Biological Markers
Surrogate Markers
Clinical Markers
Cerebrospinal Fluid
Additional relevant MeSH terms:
Motor Neuron Disease
Amyotrophic Lateral Sclerosis
Nervous System Diseases
Neuromuscular Diseases
Neurodegenerative Diseases
Central Nervous System Diseases
Spinal Cord Diseases
Pathologic Processes
TDP-43 Proteinopathies
Proteostasis Deficiencies
Metabolic Diseases
ClinicalTrials.gov processed this record on September 21, 2017


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Real San Diego Weddings: Jay + Ashleigh
For their vow exchange, Jay and Ashleigh knew they wanted to swap the drastic desert heat of Arizona for a lush, light and airy atmosphere. When they arrived at Paradise Point, these two neuroscience pros didn't have to do much thinking; they knew the tropical San Diego wedding setting would pair perfectly with their soft and sweet romance theme. Keeping in line with their vision, they became Mr. and Mrs. Turner on Island Point Lawn during the most romantic month of the year with Mission Bay as their backdrop.
Newlywed Ashleigh shares their story, inspiration, favorite memories from the big day, and what led them to have their destination wedding in San Diego.
How they met:
Jay and I both work at a hospital in Phoenix, which is where we met. I am a nurse in the neuroscience ICU and Jay is a neurosurgery resident. Around Christmas time of 2010, I was taking care of one of his patients. We started talking and felt a connection immediately. We went on our first date a few weeks later and I knew afterward that he was "the one." We became engaged 10 months later and were married on February 2, 2013 in a San Diego wedding at Paradise Point!
Why they chose a wedding in San Diego:
Jay and I both wanted a smaller, more intimate wedding. We knew we wanted to do a destination wedding to cut down the guest list size so we initially chose Hawaii. After we started planning we decided that the island would be a better honeymoon location for us rather than for a wedding. We decided on a San Diego wedding ceremony as it was close to Phoenix, but far enough to be able to keep the guest list smaller. We researched wedding venues in San Diego online and traveled over to California to choose. From the minute we stepped foot on the property of Paradise Point, we knew that it was where we wanted our wedding. We loved the tropical and peaceful feel of the environment, which reminded us of Hawaii. We toured the ceremony sites and reception halls and they were exactly what we were looking for. The guest rooms were beautiful, the food was great, and the staff was friendly, accommodating, and very helpful.
Their San Diego wedding inspiration:
Our wedding theme was romance because we liked the idea of having soft colors and lighting throughout our day. We chose ivory, petal pink and gray for our colors and roses and hydrangeas for our flowers.
Their favorite part of the big day:
Our ceremony. It was romantic, intimate, and beautiful. We could hear the subtle sound of the ocean and breeze as we stood hand-in-hand sharing our vows. The wedding ceremony venue is the main reason we chose to have our wedding at Paradise Point and it turned out perfectly!
Photography by Frank Salas


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In the Garden: Sept. 29
Updated 2:39 am, Sunday, September 30, 2012
Photo: Associated Press
Seeds for beets, carrots, collards, lettuce, mustard, parsley, garden peas, spinach, radishes and turnips can still be sown in the winter vegetable garden.
The second planting of cool-weather vegetable transplants such as 'Cheers' cabbage, Chinese cabbage, 'Green Magic' broccoli, 'Snow Crown' cauliflower, 'Vates' collards, and 'Prince Marvel' brussels sprouts should be planted now.
Plant garlic sets with each individual clove basal-end down. Plant an inch deep and space them 3 to 6 inches apart. Harvest in late May and through June when the leaves turn yellow and the flower head starts breaking apart.
Lifestyle Channel
David Rodriguez, horticulturist, Texas A&M AgriLife Extension Service