text: 2 July 2013 I don't want to die in an attic, but what choice does a member of Generation Rent have? There are too many people and not enough houses, and that the houses that do exist are either unaffordable or occupied by elderly people who, thanks to medical science – and, I should add, through no fault of their own – aren't going anywhere fast. Print HTML I can't remember when I realised I would never have my own property. Perhaps, like the fact that human beings cannot fly, or that the man I lost my virginity to was unlikely to be my future husband, it is something I have always known. And yet dapples of hope must have broken through my stoic resignation and allowed me, if only for a moment, to dream. Maybe I was drunk at the time. We are in the middle of a "housing crisis". This means, put simply, that there are too many people and not enough houses, and that the houses that do exist are either unaffordable or occupied by elderly people who, thanks to medical science – and, I should add, through no fault of their own – aren't going anywhere fast. This crisis hasn't taken anyone by surprise, and yet no one, at any point throughout my adolescence, when phrases such as "housing bubble" and "property ladder" began to seep into my consciousness – before being discarded in favour of other concerns ("Should I buy a thong? Sisqó seems to like them") – did anything about it. The result is a "squeezed generation" that has no hope of affording the average £252,798 cost of a home. If they are lucky, they will find themselves living in a perpetual flatshare or bunking up with their parents, and, if unlucky, on an interminable waiting list for social housing, or homeless. I won't talk about the other stratum of people, those who can rely on the Bank of Mum and Dad for a deposit, because I hate them. Passionately. (It could be that the unfairness of life struck me even before my university course-mates were bought their own flats in central London. Perhaps it was when I saw that my cousin's doll's house had electric lighting and real windows, while mine was roofless and inhabited by a potato with a face drawn on it.) Having done some vague calculations, I have concluded that in order to succeed in finding a non-rented roof over my head, one of two things must happen. Either the book that I am writing with my best friend must sell millions of copies – something that is unlikely, considering how it in no way describes a naive virgin's voyage of sexual discovery at the hands of a wealthy tycoon with a spanking fetish – or I must resign myself to living in a hovel that is completely in my boyfriend's name. This is assuming that he is able to get a mortgage, which is unlikely, and that he will invite me to come and live with him (also touch and go, to be honest). I am not alone in this but I am lucky in one respect, which is that my rented flat contains a living room. This is regarded as something of a luxury in my circle. Forget Elle Decoration, with its Le Creuset cookware and fairy light-festooned lifestyle porn: a living room is where it's at. That's prime housing space that could be filled by a warm, paying body, after all, and it means that you don't have to eat your dinner standing up in a poky galley kitchen, or in your room, in bed. Rents in London have become so preposterous that people are audaciously letting out spaces that push the very boundaries of habitability. A couple of years ago I went to look at an "attic room" in Kentish Town that turned out to be less room and more attic. Granted, the owners had resourcefully used some draped chiffon to conceal the loft insulation and the boiler, giving one the feeling of a sort of harem tent, but even a small person would have had trouble standing up, and my bum barely fit through the trapdoor. So yes, we need to build more houses, certainly, but there also needs to be some kind of rent control, because private landlords basically own our asses and people are living in airing cupboards, nesting next to immersion heaters. In the Times of 24 June, Tim Montgomerie rightly pointed out that what's missing from this debate is a political party that speaks for my generation. He then went on to claim, wrongly, that the Conservatives could still become that party. The Conservatives will never become that political party, because they have never not had living rooms. They expect the poor to pack their children in or pay the price in benefit cuts. Rather than capping the extortionate rents charged by private landlords, they top up the difference, encouraging the hiking of rates. They have made squatting a criminal offence. The Tories are a party of old fogeys (and that includes the young ones). This debate is dominated by a disconnect – Generation Rent v the Baby Boomers – and the Tory party represents the latter with panache. Montgomerie went on to suggest that the government create "five or six new garden cities . . . situated between London and the Midlands". Why not just put all the young people on an island and be done with us? Our big cities will become like Paris, populated by an ageing bourgeoisie with a direct line to the noise complaints department. I was born into a flatshare but I'm not sure I'd like to die in one. (Then again, I'd rather that than some kind of suburban holding pen for alienated young professionals.) The place I was born into was an ex-squat that had been let by the council to stop the building from crumbling, and one of my earliest memories is of falling down the stairs there. So, actually, I did once try to fly. It did not end well. › Morning Call: pick of the papers There just aren't enough houses. Photograph: Getty Images Rhiannon Lucy Cosslett is a writer for the New Statesman and the Guardian. She co-founded The Vagenda blog and is co-author of The Vagenda: A Zero Tolerance Guide to the Media. Subscribe from just £1 per issue This article first appeared in the 01 July 2013 issue of the New Statesman, Brazil erupts More Subscription offer 12 issues for £12 + FREE book LEARN MORE Close This week's magazine


text:
Home-based AIDS Care Project
This study has been terminated.
(Terminated by IRB for non-compliance with human subject regulations.)
Centers for Disease Control and Prevention
The AIDS Support Organization
Ministry of Health, Uganda
Information provided by (Responsible Party):
Centers for Disease Control and Prevention
ClinicalTrials.gov Identifier:
First received: July 8, 2005
Last updated: September 10, 2012
Last verified: September 2012
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Detailed Description:
The Home-based AIDS care program pilot project delivers and monitors antiretroviral (ARV) and tuberculosis (TB) medications at the homes of 1,000 people with HIV living in a rural area of Uganda. This study is evaluating how well this program reduces illness and prolongs the life of participants, changes sexual behavior, influences levels of adherence to medication, affects aspects of perceived stigma by participants and their communities, and other operational components of the program including cost-effectiveness. This study is evaluating the hypothesis that frequent home visits by a trained lay person with a standard questionnaire is equivalent in terms of health outcomes to frequent viral load and CD4 cell count measurements.
|HIV Infections
|Procedure: Laboratory and clinical monitoring regimens
|Study Type:
|Study Design:
|Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
|Official Title:
|Home-based AIDS Care Project, Tororo, Uganda
Resource links provided by NLM:
MedlinePlus related topics: HIV/AIDSU.S. FDA Resources
Further study details as provided by Centers for Disease Control and Prevention:
Primary Outcome Measures:
- Equivalence of 3 different monitoring regimens for ART
Secondary Outcome Measures:
- Sexual risk behavior
- medication adherence
- quality of life
- depression
- cost-effectiveness
- viral load
- CD4 cell count
|Study Start Date:
|May 2003
|Study Completion Date:
|March 2009
|Primary Completion Date:
|March 2009 (Final data collection date for primary outcome measure)
In Uganda, the high cost and complexity of administering antiretroviral therapy is an obstacle to full implementation country-wide. The Home-based AIDS care program (HBAC) pilot project was designed to deliver and monitor ARV and tuberculosis (TB) medications at the homes of 1,000 people with HIV living in a rural area of Uganda. In addition, the cost and complexity of frequent laboratory monitoring of viral load and CD4 cell counts is a major impediment to widespread use of ARV therapies in Uganda and other resource-limited settings. Nested within the Home-Based AIDS Care (HBAC) project, is a randomized study of strategies for monitoring ARV therapy that involves 3 arms: 1) Quarterly CD4 cell counts, viral loads and home visits by trained lay persons; 2) Quarterly CD4 cell counts and home visits; and 3) Home visits alone.
|Ages Eligible for Study:
|13 Years and older (Child, Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- HIV infection
- CD4 cell count <250 or symptomatic AIDS
- Age >13 years
- Karnofsky score >40%
- AST or ALT < 5 times normal values
- Creatinine clearance >25 ml/min
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00119093
Please refer to this study by its ClinicalTrials.gov identifier: NCT00119093
|Tororo Hospital/CDC-Uganda
|Tororo, Uganda
Sponsors and Collaborators
Centers for Disease Control and Prevention
The AIDS Support Organization
Ministry of Health, Uganda
|Principal Investigator:
|Rebecca E Bunnell, ScD, MEd
|Centers for Disease Control and Prevention
|Principal Investigator:
|Jonathan H Mermin, MD, MPH
|Centers for Disease Control and Prevention
|Principal Investigator:
|Alex Coutinho, MBChB, MPH
|The AIDS Support Organization
|Principal Investigator:
|David Moore, MD
|CDC-Uganda and University of British Columbia
|Principal Investigator:
|Jordan Tappero, MD, MPH
|Centers for Disease Control and Prevention
More Information
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Keywords provided by Centers for Disease Control and Prevention:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on September 21, 2017
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Ekwaru JP, Campbell J, Malamba S, Moore DM, Were W, Mermin J. The effect of opportunistic illness on HIV RNA viral load and CD4+ T cell count among HIV-positive adults taking antiretroviral therapy. J Int AIDS Soc. 2013 Apr 1;16:17355. doi: 10.7448/IAS.16.1.17355.
Campbell JD, Moore D, Degerman R, Kaharuza F, Were W, Muramuzi E, Odongo G, Wetaka M, Mermin J, Tappero JW. HIV-infected ugandan adults taking antiretroviral therapy with CD4 counts >200 cells/μL who discontinue cotrimoxazole prophylaxis have increased risk of malaria and diarrhea. Clin Infect Dis. 2012 Apr;54(8):1204-11. doi: 10.1093/cid/cis013. Epub 2012 Mar 14.
Mermin J, Ekwaru JP, Were W, Degerman R, Bunnell R, Kaharuza F, Downing R, Coutinho A, Solberg P, Alexander LN, Tappero J, Campbell J, Moore DM. Utility of routine viral load, CD4 cell count, and clinical monitoring among adults with HIV receiving antiretroviral therapy in Uganda: randomised trial. BMJ. 2011 Nov 9;343:d6792. doi: 10.1136/bmj.d6792.
Weidle PJ, Moore D, Mermin J, Buchacz K, Were W, Downing R, Kigozi A, Ndazima V, Peters P, Brooks JT. Liver enzymes improve over twenty-four months of first-line non-nucleoside reverse transcriptase inhibitor-based therapy in rural Uganda. AIDS Patient Care STDS. 2008 Oct;22(10):787-95. doi: 10.1089/apc.2008.0020.
|Responsible Party:
|Centers for Disease Control and Prevention
|ClinicalTrials.gov Identifier:
|NCT00119093 History of Changes
|Other Study ID Numbers:
|Study First Received:
|July 8, 2005
|Last Updated:
|September 10, 2012
Keywords provided by Centers for Disease Control and Prevention:
Antiretroviral therapy
Viral Load
Opportunistic illness
Additional relevant MeSH terms:
HIV Infections
Lentivirus Infections
Retroviridae Infections
RNA Virus Infections
Virus Diseases
Sexually Transmitted Diseases, Viral
Sexually Transmitted Diseases
Immunologic Deficiency Syndromes
Immune System Diseases
ClinicalTrials.gov processed this record on September 21, 2017

subset: commoncrawl


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Current Articles
"Save migratory birds in crisis – every species counts!" - is this year's central WMBD theme and aims to raise awareness about globally threatened migratory birds, with a particular focus on those birds on the very edge of extinction - the Critically Endangered. On 8-9 May 2010 thousands of people around the world will be attending World Migratory Bird Day (WMBD) events which will celebrate bird migration and highlight migratory birds in crisis.
"Wetlands International champions the cause for the conservation of migratory waterbirds and their habitats along the world's flyways by working closely with governments, international agreements, and people willing to make a difference through local action and international cooperation" says Dr Taej Mundkur, Programme Manager Flyways of Wetlands International.
"Migratory waterbirds serve as flagships to promote the conservation and management of wetlands to maintain their multiple ecosystem services and functions for people and biodiversity. World Migratory Bird Day 2010 is a wonderful opportunity to raise awareness of this issue globally," added Dr Mundkur.
As one of the best researched taxa, birds serve as vital indicators for the state of biodiversity and the biological health of the ecosystems they inhabit. If a bird species becomes threatened with extinction it is often a clear sign that the conditions of the required habitats have changed and that other species dependent on them may also be affected.
A staggering 1,227 or 12.4% of the total 9,865 extant bird species in the world are currently classified as globally threatened and 192 of these are considered Critically Endangered.
An estimated 19% of all known birds are considered to be migratory, of which 11% are Globally Threatened or Near Threatened and 31 are classified as Critically Endangered according to BirdLife International on behalf of the IUCN Red List.
"World Migratory Bird Day is an opportunity to draw international attention to migratory birds around a central theme each year. The focus on the most threatened migratory birds in 2010 acts as yet another reminder to governments that more needs to be done internationally to conserve these species across their migratory ranges", says Elizabeth Maruma Mrema - Executive Secretary of the Convention on Migratory Species (CMS), a UNEP administered wildlife treaty.
Critically Endangered bird species are found throughout the world in all countries and territories, with most countries supporting at least one species with this highest risk category assigned by the IUCN.
"International collaboration is the only way to conserve migratory birds as they pass along their flyways", said Dr Marco Lambertini – BirdLife's Chief Executive. "That's why the BirdLife Partnership, with over 100 national organisations across the continents, can make a great difference in providing safer routes for migratory birds, as well as promoting the crucial inter-governmental co-ordinated efforts needed to address the growing threats along the flyways".
Some prominent examples of "migratory birds in crisis" being highlighted in the context of this year's WMBD campaign include the Slender-billed Curlew (Numenius tenuirostris), the Northern Bald Ibis (Geronticus eremita), the Sociable Lapwing (Vanellus gregarius), the Waved Albatross (Phoebastria irrorata) and the Orange-bellied Parrot (Neophema chrysogaster) – all of which are migratory and listed as Critically Endangered.
These birds face a range of mainly human-driven threats, of which agriculture and invasive alien species are the most important. Hunting and trapping, logging, urbanization, pollution and fisheries are also significant threats, with climate change increasingly becoming a factor.
"It is time we listen properly to what the birds are telling us about the current state of our environment. Without immediate conservation action, there is a risk that the state of the world's biodiversity will continue to get worse and that as a result some migratory bird species, including some that fall under international wildlife treaties such as AEWA might become extinct" says Mr Lenten.
Notes to Editors
World Migratory Bird Day (WMBD)
World Migratory Bird Day (WMBD) is a global initiative devoted to celebrating migratory birds and for promoting their conservation worldwide. It is being organized by the Secretariats of the African-Eurasian Migratory Waterbird Agreement (AEWA) and the Convention on Migratory Species (CMS) – two international wildlife treaties administered by the United Nations Environment Programme (UNEP). The WMBD 2010 campaign has also received support from the following partners: UNEP, The International Year of Biodiversity (IYB), BirdLife International, Wetlands International, The Partnership for the East Asian - Australasian Flyway (EAAFP) and The World's Rarest Project.
The WMBD campaign is made possible through part of the voluntary contribution given to the AEWA Secretariat by the German Federal Ministry for the Environment, Nature Conservation and Nuclear Safety.
For more information please see the WMBD Partners page on www.worldmigratorybirdday.org
As of 6 May 2010 over 70 separate events in more than 40 countries have been registered on the campaign website. WMBD events will be celebrated in: Argentina, Australia, Austria, Bangladesh, Benin, Botswana, Burundi, Cameroon, Canada, Chile, Colombia, Croatia, Egypt, France, Germany, Hong Kong SAR (China), India, Indonesia, Israel, Italy, Ivory Coast, Kenya, ,Madagascar, Malaysia, Mongolia, Nepal, Pakistan, Puerto Rico, South Africa, Spain, the former Yugoslav Republic of Macedonia, Tunisia, Turkey, Uganda, the United States of America and Zimbabwe.
For more information please see the WMBD Around the World page on www.worldmigratorybirdday.org
World Migratory Bird Day 2010 has teamed up with this year's World's Rarest Bird Photo Competition covering the world's most threatened birds and has included an additional prize for the best photo of one of the 31 Critically Endangered birds that are migratory. Photos submitted to the international photo competition will be featured in a landmark publication – The World's Rarest Birds – which will support international conservation efforts and help fundraise for BirdLife International's Preventing Extinctions Programme. Contributors to the photo competition, whose images are published will receive a free copy of the book and also have a chance of winning a number of attractive prizes.
For more information please see the Photo Competition page on www.worldmigratorybirdday.org
A dedicated press page is available, please see: www.worldmigratorybirdday.org
2010 International Year of Biodiversity The United Nations declared 2010 the International Year of Biodiversity (IYB) to raise awareness about the crucial importance of biodiversity, to communicate the human costs of biodiversity loss, and to engage people, particularly youth, throughout the world in the fight to protect all life on Earth. Initiatives will be organized throughout the year to disseminate information, promote the protection of biodiversity and encourage countries, organizations, and individuals to take direct action to reduce biodiversity loss. The focal point for the year is the Secretariat of the Convention on Biological Diversity. For more information see: www.cbd.int/2010/welcome/
Taej Mundkur, Flyway Manager, Wetlands international Headquarters on Tel . +31 (0) 614 987 324 E-mail: email@example.com
Florian Keil, Information Officer, UNEP/AEWA Secretariat on Tel: +49 (0) 228 8152451, Mobile: +49 (0)151 14701633, E-mail:email@example.com
Francisco Rilla, Information Officer, UNEP/CMS Secretariat on Tel: +49 (0) 228 8152460, E-mail: email@example.com
or Veronika Lenarz, Senior Information Assistant, UNEP/CMS Secretariat on Tel: +49 (0) 228 8152409, E-mail: email@example.com
at UNEP:
Nick Nuttall, Spokesperson/Head of Media, UNEP on Tel: +254 20 7623084, Mobile: +254 733 632755, E-mail: firstname.lastname@example.com
at CBD / The International Year of Biodiversity:
David Ainsworth, Information Officer, Focal Point for the IYB, CBD Secretariat, Tel: +1 514 287 7025, Email: email@example.com
at BirdLife International:
Nick Askew, Communications Officer, BirdLife International on Tel: +44 (0)1223 279809, E-mail: email@example.com
at The Partnership for the East Asian - Australasian Flyway:
Aram Lee (Ms), Communication & Information Officer on Tel: +82 32 260 3004, Email: firstname.lastname@example.com
at The World's Rarest Bird Photo Competition:
Erik Hirschfeld, The World's Rarest, Tel: +44 (0) 1628 529 297, Email:email@example.com
Wetlands International Africa
Phone: +221 33 869 16 81


text:
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Emergency chlorination in Chilliwack after E.coli detected
Just as the topic of chlorination reached a fever pitch in Chilliwack after the public meeting Tuesday, a positive E.coli test result came through Wednesday morning for the area of Greendale.
It's the first known positive on the valley floor, said officials.
City of Chilliwack has issued a Water Quality Advisory for residents in Greendale on the heels of a "count one" result, which is the absolute lowest detectable level of the contaminant.
"The City has activated its standby chlorination system and is flushing the pipes in the area," said Mayor Sharon Gaetz, calling it "ironic" coming the morning after the big public meeting on chlorination.
She said in a conference call it could be a false positive, coming from contamination outside the system, but they're taking it seriously and taking precautions.
The chlorine was expected to take about 12 hours to reach Greendale, but it only took about four, said officials.
"Once the chlorine is present, residents are advised to run the water in their pipes to flush the chlorinated water through the system."
In order to chlorinate the Greendale area, the system will distribute chlorinated water to all areas of Chilliwack, which officials said was unavoidable, as it was the only way to reach the western most edge of the system.
City and Fraser Health officials said they would re-test the water to confirm results, which should be available by Thursday afternoon.


text:
Hultzen, Walker, Paxton sent down; Maurer remains
PEORIA, Ariz. -- The Mariners sent five pitchers down to the Minor Leagues on Thursday, including top prospects Danny Hultzen, Taijuan Walker and James Paxton. But interestingly, up-and-coming right-hander Brandon Maurer remains in the Major League camp after throwing four more shutout innings in an 8-7 victory over the Reds.
Hultzen and Hector Noesi, who are both on the 40-man roster, were officially optioned to Triple-A Tacoma. Three more pitchers -- Walker, Paxton and Jhonny Nunez -- were reassigned to Minor League camp since they're not on the 40-man roster.
The moves bring the Mariners' total to 51 players still in camp, including 22 pitchers.
Among those still competing is Maurer, the 22-year-old right-hander who has a 0.90 ERA with just one run allowed in 10 innings this spring. He allowed three hits and two walks with four strikeouts in shutting out the Reds from the fifth through eighth innings on Thursday. It was his longest spring stint, after Joe Saunders gave up seven runs in the first four frames.
"We had a couple starters out there pitching for us and it was a little different for Brandon coming out of the bullpen like that, but he knew he was going to pitch four innings and he did a great job," said manager Eric Wedge. "He rushed through a couple pitches at times, but he was able to fix it and that's a good sign. His stuff was good again, like it was his last outing. The baseball is doing what he wants it to do and obviously it's good stuff. So, he's been pretty impressive."
What exactly do the Mariners need to see from Maurer, who was the Southern League Pitcher of the Year last season for Double-A Jackson?
"It's a combination of things," Wedge said. "One, how he handles himself as a young pitcher. Two, just the way his stuff plays against big league hitters. And then you just look at how he continues to climb in regard to how we build him up and how he handles different situations and works through those situations. So far, we've seen all good things."
Walker and Hultzen are among the top prospects in baseball, but Walker is just 20 and has yet to pitch above Double-A ball and Hultzen -- the second overall pick in the 2011 Draft -- missed a week of camp with a sore hip and has thrown just four innings this spring.
Greg Johns is a reporter for MLB.com. Follow him on Twitter @GregJohnsMLB as well as his Mariners Musings blog. This story was not subject to the approval of Major League Baseball or its clubs.


text:
retrofuturist wrote:It seems like it was just a hosting/server issue... a useful test in the future is to see if David's other sites like http://www.thedhamma.com/ or http://www.dhammawiki.com/ are working. If they're not working either, it's likely to be a hosting/server issue rather than something wrong with the Dhamma Wheel software/database.
Dan74 wrote:Another proof of the superiority of Zen (and Mahayana) over Theravada - when ZFI goes down we get mysterious multiple error messages, and when Dhamma Wheel goes down, all we get is the "server not found"!
I rest my case.
PS Good to see it back online!
Dan74 wrote: "server not found"!
TheDhamma wrote:Dan74 wrote: "server not found"!
aka, "self" not found -- anatta.
nathan wrote:still getting an sql error message after every post
I've had that going for a long time with the computers, impermanence is pretty up front online. There is hardly a bit of what the net was back in '85 that even exists anywhere in the world today except maybe the odd server rack! Until the house burned down (talk about instructive!) I had a stack of older computer systems that grew in height every couple of years until I switched to apple when they picked up the unix os. No looking back on that one but the impermanence factor keeps ramping up steadily, I don't think I have had a version of the os that didn't get an upgrade every week for the last five years now!Dan74 wrote:nathan wrote:still getting an sql error message after every post
This is obviously to teach us equanimity and non-attachment to our posts and to the internet in general.
Users browsing this forum: No registered users and 48 guests


text: Researchers in a lab study fed obese rats a high-fat (47 percent), moderate carbohydrate, pro-inflammatory Western-type diet, enriched with anti-inflammatory tart cherry. After 90 days, levels of blood sugar, triglycerides, cholesterol and several signs of inflammation all were much lower. Body weight, total fat mass and abdominal fat were also lower, while lean body mass increased. "Chronic inflammation is a whole body condition that can affect overall health, especially when it comes to the heart," said study co-author Mitch Seymour, Ph.D., at the University of Michigan. "This study offers further promise that foods rich in antioxidants, such as cherries, could potentially reduce inflammation and have the potential to lower disease risk."


text:
PRIK | STICK by Brynjar Sigurðarson
Birch and nylon string. 180 cm long. The sticks are produced according to demand.
Brynjar Sigurðarson graduated from ECAL, Lausanne, in 2011, following a BA from The Iceland Academy of the Arts (IAA). For his graduation project at the IAA he embarked on a trip to Vopnafjörður (weapon-fjord), a small rural community in the North East of Iceland. The products of his research were furniture objects with no defined functions. Now Brynjar has revisited the project and added to it a collection of sticks. Like the original furniture objects, the sticks have no defined function. Sticks are part of our childhood and the element of play is always present. Sticks have a strong reference to tools and weapons and have been used as an extension to our bodies as well as for support.
Verð: ISK 65.000


text:
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6 Ways Women's Wrestling Can Be Saved
by, 10-06-2012 at 10:22 AM (8577 Views)
WWE: Maintain good pace of Divas Matches
If there's one thing that WWE is doing right, it's allowing Divas matches extended time not only on the new 3-hour RAW, but on the 2-hour Smackdown. What I've seen from the past two months is just the right amount of time for them and they get more ring time on occasion than Clay, Barrett, Tensai, etc. But if Divas matches went on for any longer I'd fear that everybody would get bored of them, as believed as the main problem of the Divas before they changed their booking scheme. But so far it's been good, and I hope they just keep it up. Then again this is the WWE we're talking about. A promotion full of fear and doubt.
TNA: Fire Bruce Pritchard and Gail Kim
Ever since Gail Kim ran from the WWE like a little girl and headed to the nearest private jet to Orlando, the Knockout Division has been going downhill ever since. She's hogged the KO title and the tag titles and what happens? Velvet Sky's push = dead, Winter's push = dead, and everybody else other than Mickie and Madison are afterthoughts. Really? You're willing to turn your women's division in the wrong direction just so Gail can get what she wants? Pritchard has also been known to not be a big supporter of women's wrestling, and now we are only seeing two or three Knockouts per episode on a regular basis. Pritchard's authority played a factor in the Beautiful People leaving, which is a huge shocker to me if true.
WWE: Get the Divas Championship off of Eve
I cannot stand Eve. I think she is overrated and has gotten too much attention than what she needs. I cannot take away that she has decent promo skills, is very athletic, and has a strong BJJ background. I get that. But Eve is hardly a draw, she's a very irritating space occupier who is ruining the chances of other women who could use them like Naomi, Tamina, even Natalya again. How come AJ can't wrestle while in a role and Eve can? How much attention can you give one woman in two years? We all know how Vince is obsessed with this woman but she isn't that special.
TNA: Search the Indies for more talent
There are only six Knockouts that TNA books on an ordinary basis. Scary huh? Well out of those six, only two Knockout out of those six never worked for WWE, that being Madison Rayne and ODB. TNA needs to find new, never been seen before women. We know Mickie James and Tara have established themselves already in WWE, because if it weren't for WWE, they wouldn't be in TNA right now. Since the start of 2011, only two new women have been called up from TNA, Rosita and Taeler Hendrix, who are still rather underused. Introduce us to some more homegrown talent. If they can be developed well then we won't know what to expect out of them and we can think "Wow, TNA did a good job with this woman. They don't need to rely on WWE people all the time."
WWE: Sign the Beautiful People
I don't know about you people who don't want them to go there, I'd like to know how many of you are willing to drive all the way to New York to see them compete in someone's backyard & tell me how that's not a waste of their time. They need WWE and WWE needs them; They know without WWE, they wouldn't have the careers that they do. It's certain they would be more than willing to receive 2nd opportuities in the #1 promotion, because very few wrestlers ever do. Regardless of their age, they would be a breath of fresh air to the Divas Division; Angelina I'm certain is very determined to add more titles and accomplishments to her career and follow Trish and Lita, while Velvet could be the next Kelly Kelly and be exposed to much larger markets than in TNA. Velvet's new clothing line I'm sure is a test for her to prove how well she can draw on her own and try to help her chances with WWE while trying to fade her image as TNA's resident sexpot. There is a very elaborate blog about them which I recommend you read if you haven't already.
TNA: Send Brooke Hogan packing
Brooke has been a total flop right off the bat. I understand her role is only an on screen character but couldn't Dixie or the Hulkster bring in anybody else he's friends with in the whole world with more prominence? Brooke is certainly not helping with ratings or making the product any believable, so why is she still around? If TNA keep bragging about their strong women's division, why do they need a boss who is a lot younger and with no wrestling experience? I mean Tara was a toddler when Brooke was born. I know it's gonna be very hard to oust Pritchard, but Brooke can easily be taken care of and she can wander off to go be a rich blond socialite. That's all she is since her singing career flopped.


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Just wondering if you play and like console RPGs or PC RPGs more? In the console you get more story and it's
mostly turn based battle systems and random battles. Also most of them originate in Japan.
With PC it's more about the online playing now, and real time fighting with more of a quest driven story
line. Also I've notices that the console RPGs are more cinematic then the ones on the PC.
PC RPGs allow for way more character development and customization though. I suppose becuase of the input
devces available to the common PC?
What do YOU think? Why are there these difference between console RPGs and PC RPGs?
hmmm, do you get more story on a console ??? i think pc rpgs almost always are based on real pen & paper rpgs while console rpgs, as you said, most of the time follow the japanese style of rpg/adventure. i like both types so i couldn't say that i prefere one over the other. it's just too different to really compare. these differences clearly orignate from a) the different input capabilities and B) the different gfx capabilities.
I've never really liked using joypads for certain genres. FPSs mainly, but also other types. I don't have a console myself, but I play on a friends gamecube quite a lot, and one RPG that is quite good is Phantasy Star Online. I enjoy playing that.
However, given the choice I'd always pick a PC game over a Console game. Bar none.
i always prefer consoles, no mather for what game.. though the combination of joypad and keyboard would be best.. then again, i would need 4 arms and hands to play:D
hm right, i would need the keyboard for chatting only anyways, so i guess joypad and headset is the solution:D
fps + strategy games... i need a keyboard and a mouse for both of them. i refuse to use a joypad for this, especially fps. the dreamcast had a pretty good keybaord and mouse equipment as far as i remember
i don't play rts myself often.. but yes, mouse and keyboard are way to go there..
for fps.. i've played goldeneye, turok2, halo, metroid prime. they all played great.. and where more fun than any fps on pc till now. i don't like the typical pc fps.. they are all the same.. i find them boring.
halo was great on the xbox... still they had to heavily modify the levels, meaning they had to add a million new enemys because a joypad can never compete with a keyboard/mouse.
well yeah i suppose for an _fps_ the ideal input device would be keyboard + mouse. But Ive also played FPSs on consoles. I must say that I agree with deveperman, I like console FPSs rather then the PC ones. Even though I dont like FPSs in general, I dont mind golden eye for the n64, I think that's my favourite FPS ive played to date.
However, keyboard + mouse dosnt make an RPG better to play. I think using a keboard and a mouse for an RPG just adds extra unneeded complexity. On the console you have a simple inventory and action button, plus movement. On the PC if you play an RPG it takes you longer to actually learn HOW to play the dang thing then it takes you to finish the game. PC RPGs I guess are more catered towards teh hardcore gamer and not the casual gamer.
Also is it just me or are the stories in the console RPG way more far-fetched the the PC ones. They seem to be more fantasy
i think pc rpgs are more complex because they are often based on pen and paper rpgs. this also has a great influence on the story since its bound to the world of a particular p&p rpg.
i'm not one for console anything.... i'm totaly a PC person.
Its not that PC RPGs are more complex. well maybe in a way, but not in everything. probably the character development aspect of PC RPGs are more complex....but not the sroty lines. and the story is half the catch for an RPG
i've yet to find any pc game that is as detailed, and as complete designed as a typical nintendo game.. never found one yet..
:blink: :blink:
first of all, what do you mean by "typical nintendo game". What exactly is a typlical nintendo game?
most mario games, yoshi games, zelda games, metroid games, and some other (f.e. starfox).
all those bigger ones simply. i don't take pokemon into my list as it is simply not the gamestyle i like. but it would count to them, too, i guess..
Well, the latest Starfox game was a Rare game, unless I'm mistaken .
i know. i was talking about starfox64 actually, the one i know.. the other one is an adventure, and, while it can be good, it has not much to do with the original starfox.
but nobody is gonna miss it.. if you followed irc you know why:D
most mario games, yoshi games, zelda games, metroid games, and some other (f.e. starfox). all those bigger ones simply. i don't take pokemon into my list as it is simply not the gamestyle i like. but it would count to them, too, i guess..
ah ok i c. I'd probably agree on zelda type games. But for mario type games I'd say jak and daxter could whip his butt. Now THAT was a detailed and more completely designed game that is similar to mario. Although....that's not a PC game, so I guess your statement still stands . But Im also not the typical PC player, Im biased towards console games.
My reasons for voting PC "RPG" over the console equivalent are that I haven't seen any Console NuHuGs [[http://www.ishpeck.net/index.php?J=ishpeck&journalOffset=2003-09-11+00%3A00%3A01]](http://www.ishpeck.net/index.php?J=ishpeck&journalOffset=2003-09-11+00%3A00%3A01]) that I enjoyed. There are far too many Final Fantasy clones out there and not enough Fallout / Planescape: Torment clones.
My reasons for voting PC "RPG" over the console equivalent are that I haven't seen any Console NuHuGs (http://www.ishpeck.net/index.php?J=ishpeck&journalOffset=2003-09-11+00%3A00%3A01) that I enjoyed. There are far too many Final Fantasy clones out there and not enough Fallout / Planescape: Torment clones.
I suppose it's a matter of opinion. For me it's completely the opposite: I would say "There are far too many fallout/planetscape clones out there and not enough final fantasy clones"
as for your "NuHuGs" theory (catchy name by the way). I suppose to some extent, RPGs are all about statistics, but that's one of the reason I like console RPGs more then PC RPGs. With console RPGs its more about the role, becuase the stories are much deeper. I've always hated PC RPGs, mainly because they try to be so close to the pen and paper RPGs that people play with those D&D rules and all. I find them really complicated. Too much statistics and numbers and stuff. Steep learning curve for someone who's not a hardcore RPG player...
Yesterday Interplay fired of the whole staff of Black Isle (creators of Baldur's Gate, Fallout, Planescape Torment, Icewind Dale, Lionheart). Without any notice the team was fired 2 weeks before Christmas, and the project Van Bauren they were working on was announced that it was in fact Fallout 3, but now will not be continued.
\< news from gamedev >
Ishpeck so much for more fallout games somebody should teach those guys at interplay a lesson !


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Did You Know?
Snow Leopards have powerful legs and are tremendous leapers, able to jump as far as 50 feet!
Amy Morris, APR
LANSING, Mich. – Bella, a 15-year-old female gray wolf at Potter Park Zoo, passed away yesterday following age-related health issues.
"We are sad to see Bella pass, but are fortunate to know she lived far beyond her life expectancy and received excellent care with us at Potter Park Zoo," said Sherrie Graham, Executive Director at Potter Park Zoo. "Bella had a wonderful life and she will surely be missed."
Bella arrived at the zoo April 10, 2009, and has shared a habitat with fellow female gray wolf, Tala, who arrived at Potter Park Zoo in 2012 from New York. Bella came from Wildlife Science Center in Forest Lake Minnesota and was born January 1, 1999.
"Everyone here at Potter Park Zoo is sad to see Bella pass, she had become a favorite of staff and zoo visitors," said Cynthia Wagner, Animal Curator at Potter Park Zoo. "We are thankful Bella was able to be part of Potter Park Zoo and look forward to bringing in a young wolf soon."
The gray wolf, also known as the timber wolf, is the most endangered wolf in North America according to the Association of Zoos and Aquariums. The Gray Wolf Species Survival Plan Program manage more than 340 individuals at 47 AZA-accredited institutions, including Potter Park Zoo. Potter Park Zoo is proud to play a role in the conservation of these animals nationwide.


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Brianna Stanley was not a runaway bride, but she was a bride on the run last Sunday. She and fiancé Jeffrey Campbell raced together in the Carlsbad Tri-City Medical Center Half-Marathon (her first, his third). He wore a tuxedo T-shirt while she sported a garter and a white ball cap that said "Bride" and had a veil in the back.
Brianna crossed the finish line clutching a bouquet of white flowers thrust into her hands by her mother a short distance back. They had time to catch their breath as their minister (Jeffrey's dad, Scott Campbell, of Ramona) finished the full marathon before conducting their vows.
"We didn't want to do something traditional," said Brianna, a San Diego State graduate who plans to attend med school. Jeffrey is in the Navy. The marathon was fitting because they met while jogging at Mission Trails Park. Brianna noted they probably won't enter the Carlsbad event every year but are eyeing their sixth anniversary when Jan. 27 again falls on race day.
Hospital humor: Longtime local TV meteorologist Loren Nancarrow is weathering his own personal crisis, details of which he shared on his blog and via Facebook. After experiencing strange symptoms, including ringing in his ears, numbness in his hands and slurred speech, he underwent an MRI Sunday.
A plum-sized tumor was discovered that Loren quickly nicknamed the "Blob." He'll undergo surgery Thursday to remove it. After blogging that his "strength will come from humor – not worry," he received a flurry of online sympathy and "tumor humor."
He got comments such as: "It will be a successful blobectomy." "Loren, is it inappropriate to say you look cute in a green hospital gown?" And: "If you wake up spouting Sarah Palin, you better check that they did not do a lobotomy!" Or, as Loren would put it, a "blobotomy." Here's wishing him the best of luck.
From the ashes: On Oct. 21, 2007, Kit and Karen Sickels lost about 3,000 avocado trees, 2000 olive trees, 800 oaks and 1,500 grape vines as wild fire scorched the Ramona countryside and the 110-acre Milagro Farm Vineyards they had started in 2001. Also gone was a home-sized designer tree house, the La Jolla couple's second residence.
But they didn't throw in the trowel. They've since expanded from two to 11 grape varietals and opened a tasting room. On Jan. 20, competing against big-name wineries in the 2013 Winemaker Challenge, the tiny winemaking operation won rosé and sauvignon blanc best of show and best of class awards for its 2012 Rosé of Sangiovese and 2012 Sauvignon Blanc. Its 2010 Barbera won gold and its Meritage won silver.
Sickels says his secret, aside from hiring winemaker Jim Hart, is "staying out of the way of people who know what they're doing."


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Calligraphy Pens to Create Fine Invitations and Documents
Keep calligraphy pens, markers and inks on hand to let your staff create hand-lettered proclamations, diplomas and invitations. Customers to your crafts shop appreciate having access to chiseled markers and inks as well as starter kits.
Calligraphy Markers Provide a Sharp Look Without Mess
Whether you're hand-labeling gift cards for your boutique or addressing formal invitations for your event planning company, calligraphy markers can help you turn ordinary printing into a work of art. Felt tip markers with a chiseled edge automatically produce a calligraphic look with any handwriting, and the acid-free ink doesn't bleed through envelopes. Keep a good supply of basic black calligraphy markers on hand for basic lettering tasks, and choose from a vast array of colors to match invitations and gift wrap.
Calligraphy Inks to Provide a Traditional Look
When nothing but the finest traditional calligraphy will do, choose calligraphy inks that flow smoothly, so each hand-lettered word is perfect on the page, with no flubs or errant marks. Stock up on these inks in your craft store, pairing them with airbrush equipment and rubber stamps to provide your customers with great versatility. Quill carries a wide variety of colors and types, including iridescent metallic colors and brilliant, single-pigment choices with high permanence ratings for diplomas and other official proclamations.
Calligraphy Kits to Get You Started
Your crafting store or your school's art classroom isn't complete without starter calligraphy kits to help beginners learning this fine art. Kits contain traditional calligraphy pens with multiple nibs and ink cartridges in multiple colors. Keep ink refills on hand to help new calligraphers expand their repertoire.


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Ex-vivo Perfusion and Ventilation of Lungs Recovered From Non-Heart-Beating Donors to Assess Transplant Suitability
This study has suspended participant recruitment.
(Funding suspended, currently seeking other funding source(s).)
University of North Carolina, Chapel Hill
Duke University
National Heart, Lung, and Blood Institute (NHLBI)
XVIVO Perfusion
Information provided by (Responsible Party):
Tom Egan, MD,MsC, University of North Carolina, Chapel Hill
ClinicalTrials.gov Identifier:
First received: June 6, 2012
Last updated: July 8, 2016
Last verified: July 2016
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
The purpose of this research study is to learn about the safety of transplanting lungs obtained from non-heart-beating donors (NHBDs) that have been ventilated (attached to a breathing machine or ventilator to deliver oxygen) and perfused with a lung perfusion solution (Steen solution™, made by Vitrolife). This ventilation and perfusion will be done outside the body (ex-vivo) in a modified cardiopulmonary bypass circuit (the kind of device used routinely during most heart surgeries). The purpose of performing ex-vivo perfusion and ventilation is to learn how well the lungs work, and whether they are likely safe to transplant.
|Emphysema Chronic Obstructive Pulmonary Disease (COPD) Cystic Fibrosis Pulmonary Fibrosis Bronchiectasis Sarcoidosis Pulmonary Hypertension Alpha-1 Antitrypsin Deficiency
|Procedure: Transplantation of lungs obtained from Non-Heart-Beating Donors (NHBDs) after ex-vivo perfusion w/ STEEN Solution™ Device: STEEN Solution™
|Phase 2
|Study Type:
|Study Design:
|Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
|Official Title:
|Ex-vivo Perfusion and Ventilation of Lungs Recovered From Non-Heart-Beating Donors to Assess Transplant Suitability
Resource links provided by NLM:
Genetics Home Reference related topics: alpha-1 antitrypsin deficiency cystic fibrosis
Genetic and Rare Diseases Information Center resources: Cystic Fibrosis Alpha-1 Antitrypsin DeficiencyU.S. FDA Resources
Further study details as provided by Tom Egan, MD,MsC, University of North Carolina, Chapel Hill:
Primary Outcome Measures:
- 30 Day Mortality and Graft Survival [ Time Frame: 30 Days ]The primary objective evaluated for this study is recipient mortality and graft survival at 30 days post transplant. 30 day mortality and graft survival is used as a standard research assessment to evaluate post transplant outcomes.
- Primary Lung Graft Dysfunction (PGD) [ Time Frame: 24 and 72 hours ]Primary Lung Graft Dysfunction (PGD) is an indicator for significant morbidity and mortality after lung transplantation.
Secondary Outcome Measures:
- ICU Length of Stay [ Time Frame: Time to Discharge. ]The length of ICU stay is another standard research and clinical outcome assessment post transplant and has been selected as a secondary objective.
- Day 7 Ventilator/ECMO Status [ Time Frame: 7 Days Post Transplant. ]7 days ventilator or extra-corporeal membrane oxygenator (ECMO) free are being evaluated as secondary objectives.
- Recipient mortality at 12 months. [ Time Frame: 12 months ]Recipient mortality at 12 months post transplant is being evaluated as a secondary objective.
- Bronchiolitis Obliterans Syndrome (BOS) free graft survival. [ Time Frame: 12 Months ]Bronchiolitis Obliterans Syndrome (BOS) free graft survival at 12 months is being used as a secondary outcome.
|Estimated Enrollment:
|Study Start Date:
|September 2013
|Estimated Study Completion Date:
|July 2018
|Estimated Primary Completion Date:
|July 2017 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: Ex-vivo lung perfusion with STEEN Solution™
The perfusion of the lungs will be performed using STEEN Solution™. The lungs will be physiologically assessed during ex vivo perfusion with STEEN Solution™ perfusate.
Procedure: Transplantation of lungs obtained from Non-Heart-Beating Donors (NHBDs) after ex-vivo perfusion w/ STEEN Solution™
After EVLP, lungs will be cooled in the circuit to room temperature, then flushed with cold Perfadex™, and taken to UNCH where they will have an ex-vivo CT scan. Lungs determined suitable will be offered to consented patients at UNC Hospitals and Duke University Medical Center based on Lung Allocation Score. Lungs not considered for transplantation may be subjected to different experiments but are not to be a part of this research study. In summary, lungs with good and stable function during EVLP will be transplanted into recipients as per current clinical practice.Device: STEEN Solution™
This solution is a buffered dextran and albumin-containing extracellular perfusate with an optimal colloid osmotic pressure developed specifically for extra-corporeal perfusion of lungs.
No Intervention: Lung transplant from conventional brain-dead organ donor
No experimental procedures will be carried out.
|Ages Eligible for Study:
|15 Years and older (Child, Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- A recipient must meet the following requirement to enroll into the study:
- Requires a single or bilateral lung transplant and is listed for transplant at UNC or Duke
- Male or Female, 15 years of age or older.
- Subject or Subject's Representative provides a legally effective informed consent.
- Recipient does not have HIV, active Hepatitis or is colonized with Burkholderia cepacia.
- Potential subjects who have undergone previous lung transplants and meet all other inclusion criteria, are eligible for study participation.
Exclusion Criteria:
•Recipient fails to meet standard of care requirements for lung transplant, or decides not to participate.
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01615484
Please refer to this study by its ClinicalTrials.gov identifier: NCT01615484
|United States, North Carolina
|UNC-Chapel Hill
|Chapel Hill, North Carolina, United States, 27599
|Duke University Medical Center
|Durham, North Carolina, United States, 27710
Sponsors and Collaborators
University of North Carolina, Chapel Hill
Duke University
National Heart, Lung, and Blood Institute (NHLBI)
XVIVO Perfusion
|Principal Investigator:
|Thomas M. Egan, MD, MSc.
|UNC-Chapel Hill
More Information
Keywords provided by Tom Egan, MD,MsC, University of North Carolina, Chapel Hill:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on September 21, 2017
Orens JB, Estenne M, Arcasoy S, Conte JV, Corris P, Egan JJ, Egan T, Keshavjee S, Knoop C, Kotloff R, Martinez FJ, Nathan S, Palmer S, Patterson A, Singer L, Snell G, Studer S, Vachiery JL, Glanville AR; Pulmonary Scientific Council of the International Society for Heart and Lung Transplantation. International guidelines for the selection of lung transplant candidates: 2006 update--a consensus report from the Pulmonary Scientific Council of the International Society for Heart and Lung Transplantation. J Heart Lung Transplant. 2006 Jul;25(7):745-55.
Ingemansson R, Eyjolfsson A, Mared L, Pierre L, Algotsson L, Ekmehag B, Gustafsson R, Johnsson P, Koul B, Lindstedt S, Lührs C, Sjöberg T, Steen S. Clinical transplantation of initially rejected donor lungs after reconditioning ex vivo. Ann Thorac Surg. 2009 Jan;87(1):255-60. doi: 10.1016/j.athoracsur.2008.09.049.
Mason DP, Thuita L, Alster JM, Murthy SC, Budev MM, Mehta AC, Pettersson GB, Blackstone EH. Should lung transplantation be performed using donation after cardiac death? The United States experience. J Thorac Cardiovasc Surg. 2008 Oct;136(4):1061-6. doi: 10.1016/j.jtcvs.2008.04.023.
Cypel M, Yeung JC, Hirayama S, Rubacha M, Fischer S, Anraku M, Sato M, Harwood S, Pierre A, Waddell TK, de Perrot M, Liu M, Keshavjee S. Technique for prolonged normothermic ex vivo lung perfusion. J Heart Lung Transplant. 2008 Dec;27(12):1319-25. doi: 10.1016/j.healun.2008.09.003.
Egan TM, Haithcock JA, Nicotra WA, Koukoulis G, Inokawa H, Sevala M, Molina PL, Funkhouser WK, Mattice BJ. Ex vivo evaluation of human lungs for transplant suitability. Ann Thorac Surg. 2006 Apr;81(4):1205-13.
Christie JD, Carby M, Bag R, Corris P, Hertz M, Weill D; ISHLT Working Group on Primary Lung Graft Dysfunction. Report of the ISHLT Working Group on Primary Lung Graft Dysfunction part II: definition. A consensus statement of the International Society for Heart and Lung Transplantation. J Heart Lung Transplant. 2005 Oct;24(10):1454-9. Epub 2005 Jun 4.
Kim IK, Bedi DS, Denecke C, Ge X, Tullius SG. Impact of innate and adaptive immunity on rejection and tolerance. Transplantation. 2008 Oct 15;86(7):889-94. doi: 10.1097/TP.0b013e318186ac4a. Review.
Moers C, Smits JM, Maathuis MH, Treckmann J, van Gelder F, Napieralski BP, van Kasterop-Kutz M, van der Heide JJ, Squifflet JP, van Heurn E, Kirste GR, Rahmel A, Leuvenink HG, Paul A, Pirenne J, Ploeg RJ. Machine perfusion or cold storage in deceased-donor kidney transplantation. N Engl J Med. 2009 Jan 1;360(1):7-19. doi: 10.1056/NEJMoa0802289.
Cypel M, Liu M, Rubacha M, Yeung JC, Hirayama S, Anraku M, Sato M, Medin J, Davidson BL, de Perrot M, Waddell TK, Slutsky AS, Keshavjee S. Functional repair of human donor lungs by IL-10 gene therapy. Sci Transl Med. 2009 Oct 28;1(4):4ra9. doi: 10.1126/scitranslmed.3000266.
Cypel M, Yeung JC, Liu M, Anraku M, Chen F, Karolak W, Sato M, Laratta J, Azad S, Madonik M, Chow CW, Chaparro C, Hutcheon M, Singer LG, Slutsky AS, Yasufuku K, de Perrot M, Pierre AF, Waddell TK, Keshavjee S. Normothermic ex vivo lung perfusion in clinical lung transplantation. N Engl J Med. 2011 Apr 14;364(15):1431-40. doi: 10.1056/NEJMoa1014597.
|Responsible Party:
|Tom Egan, MD,MsC, Professor of Surgery, University of North Carolina, Chapel Hill
|ClinicalTrials.gov Identifier:
|NCT01615484 History of Changes
|Other Study ID Numbers:
UNC-002 Vitrolife
1UM1HL113115-01A1 ( U.S. NIH Grant/Contract )
|Study First Received:
|June 6, 2012
|Last Updated:
|July 8, 2016
|Individual Participant Data (IPD) Sharing Statement:
|Plan to Share IPD:
|Plan Description:
|De-identified individual clinical outcome data will be made available upon request
Keywords provided by Tom Egan, MD,MsC, University of North Carolina, Chapel Hill:
Lung Transplant
Chronic Obstructive Pulmonary Disease (COPD)
Cystic Fibrosis
Pulmonary Fibrosis
Pulmonary Hypertension
Alpha-1 Antitrypsin Deficiency
Additional relevant MeSH terms:
Lung Diseases
Lung Diseases, Obstructive
Pulmonary Disease, Chronic Obstructive
Cystic Fibrosis
Hypertension, Pulmonary
Pulmonary Fibrosis
Pulmonary Emphysema
Alpha 1-Antitrypsin Deficiency
Vascular Diseases
Cardiovascular Diseases
Respiratory Tract Diseases
Pathologic Processes
Pancreatic Diseases
Digestive System Diseases
Genetic Diseases, Inborn
Infant, Newborn, Diseases
Lymphoproliferative Disorders
Lymphatic Diseases
Bronchial Diseases
Liver Diseases
Subcutaneous Emphysema
Pharmaceutical Solutions
ClinicalTrials.gov processed this record on September 21, 2017


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Find the best Garages and Car Repairs in Coleford with Who Can Fix My Car.
Enter your registration to compare prices and reviews and find a great garage today.
Find the best Garages and Car Repairs in Coleford with Who Can Fix My Car.
"Forest of Dean Tyres started in 1989 with just two employees, one unit and one van. We catered for just car and commercial tyres, with very limited stock. Over the years, the tyre side of it grew due to a good reputation of service and price. With that, our valued customers began to ask for more services and for us to look after their vehicles in other ways. Such questions as 'can you fix my exhaust' and 'can you MOT & service my vehicle?' were asked and so we decided to cater for these needs working with our customers. We went on to install our MOT bay, which then lead to the service bay being installed to do the repairs. This allowed us to offer the best service and value our customers came to expect from Forest of Dean Tyre. 20 years later, the business has grown to what it is today, with fifteen employee's, four tyre breakdown vans, and eight units with a tyre stock to the value of over one hundred and fifty thousand pounds. We now offer the full package to look after your vehicle covering all the options with the philosophy of giving the best service we can. As for the future we always look forward, and as the vehicles change, we change with them. Investing in the latest equipment and products, we will always be there, with advice and help to keep you safe and on the road."


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Baidu's Margins Falling, Maxim Still Sees 15% Downside
Even following the recent selloff, China's internet stocks are having a great year. Not Baidu (BIDU), however. While Qihoo 360 technology (QIHU) has surged 45% so far in 2013, and Sohu.com (SOHU) has jumped 23%, poor Baidu has fallen 11%.
One of the big reasons for Baidu's underperformance has been its falling profit margins. There's been some hope that margins could be stabilizing, but Maxim Group's Echo He says they have more room to drop. He writes:
Fast developing competition makes it increasingly difficult for BIDU to contain users in its own network, BIDU has to rely more on Union members especially contexture ads to grow revenue, driving TAC (traffic acquisition cost, 11% of net revenue in 1Q13 vs. 8.4% a year ago) sequentially higher going forward. Increased competition and investment in mobile market and verticals will likely drive up BIDU's S&M expenses. Also supporting iQiyi and PPS will likely drive up content costs.
Some of this is already priced into the stock but analysts are likely too optimistic about Baidu's prospects, He says. He writes:
Consensus, although down consecutively, may have to further revise down. BIDU's margins should continue to decline in the foreseeable future. We estimate gross margin to decline to 70.4% in 2013 and 68.4% in 2014 as a result of higher TAC and content costs. We also estimate operating margin to decline to 42.1% in 2013 and 39.3% in 2014 mainly due to higher SG&A expenses.
He lowered 2013 EPS to $4.87 from $5.15, and cut 2014 EPS to $5.87 from $6.29, with a price target of $75.
Baidu has dropped 0.3% today to $89.65.


text:
Topic: meeting with surgeon again
I woke up today all nervous about finding out the results of yesterday's CT scan. Checked my email before I left and there's an email from MSKCC. Wondering if it was another bill, I timidly opened it, and saw that I had a new appt. acheduled. So I clicked, and there is an appt. set up with Dr. Fong!! I was so excited! That meant, to me, that the scan was good!! Right???
So I wait the whole way in to NYC and then 2 hours past my appt. time to see Dr. Kemeny. She confirmed the scan was mostly good. The tumor is about the same size but shows some necrosis. The GREAT news is that the nodes are about 1/2 the size of pre-radiation, with lots of signs of necrosis!!
I told her I assumed it was good news when I saw the appt. for Dr. F. She said she would not recommend surgery yet She wants to wait to see how the radiation continues to affect the areas. The concern I have is the tumor didn't respond that well to the radiation. Maybe I should talk to her about going back on Xeloda? It responded to that, and if the nodes are shrinking, maybe a double blast will do good. Something I need to think about. Getting that tumor back down is a must...
But the news was good, so since I don't get to post here often, I'm grabbing the excuse!!!
"Don't just have minutes in the day; have moments in time."
Any opinions I give are based on personal experiences, and are not based on medical knowledge. I strongly suggest receiving medical care and opinions.


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Network Switch, Router Switch, Wireless Network Switch and Gigabit Switch
Network Switch, Router Switch, Wireless Network Switch and Gigabit Switch Overview
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Are you IBDetermined?
Last winter, the Crohn's and Colitis Foundation (CCFA) approached me about helping film a new web campaign. The campaign was aimed to educate patients and those affected by IBD on different aspects of Crohn's disease and ulcerative colitis. I was given a list of questions and a film studio address and was told to bring bright-colored outfit options. I was completely clueless as to what to expect, and had absolutely no idea what I was going to do or say once I got on camera. I figured… who is really going to see this anyway?
I arrived at the studio in the afternoon (which was unfortunate because the other people taping that day had already worn most of the colors that I had with me). Nevertheless, I persevered and sat on a box in front of a white screen (I'm too short for the comfy chair that everyone else got). There was an interviewer, a bunch of camera/sound people, a woman that got hostile every time I touched my hair, and a few CCFA people hanging out in the darkened recesses of the studio. Then the questions started.
The first few questions were pretty easy, things I talk about all of the time. How long have you had IBD? What kinds of medications do you take? Then as I yapped, the CCFA people started to throw random questions at me about my life with IBD. I started telling stories about growing up with Crohn's, people's reactions when I was sick, how my family handled the flares, and dealing with denial. I usually talk about these things one-on-one with other people that have IBD, but after one particular story I looked up to see others in the room trying not to mess up the audio by sniffling or rustling tissues. I perked up and said, "My mom is going to kill me for telling these stories on camera." They reassured me that these stories would help someone else with IBD, but fortunately most of the sniffle-inducing stories were left on the cutting room floor.
When I left the soundstage, I realized my friend Andrea (also featured in the video) was outside watching me the whole time. I'm glad that we got to share this crazy, once-in-a-lifetime experience together and even more grateful that I was given the opportunity to participate in something that hopefully lots of IBD patients and their families will watch. To see the website go to ibdetermined.org. My video is in the "Treatment" section — but you should go through all four sections to learn more about different issues concerning life with Crohn's and ulcerative colitis.


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Now that winter's chill has torn through the country in earnest, it's important to ensure that your exposed skin stays hydrated as you move from place to place. There's nothing more frustrating than chapped hands or dry limbs, and unless you're paying attention to the warning signs, itchy patches of red, dry skin might creep up on you.
Support hydration with your diet
There are ways to prevent the effects of cold weather from the inside out. According to Health Magazine, foods high in water content, such as cucumbers, iceberg lettuce and celery, add bursts of hydration that help provide the body with extra moisture. By adding a few of these greens to your diet everyday, you'll be doing your body a favor by providing it with water from the foods you're eating as well as the liquids you're drinking.
Drink a lot of water
Although we might be inclined to reach for another cup of coffee to warm our bones, consider fueling up with another cup of water, too. There's nothing wrong with a little extra caffeine, but during these winter months especially, your body is craving additional hydration. While the effects of coffee on the body have been hotly contested, there's one surefire way to rise above the rumors - fit an extra few cups of water into your daily routine. By consciously working toward this effort, you'll be on your way to achieving a healthier winter lifestyle without worrying over liquid volumes or caffeine intake.
Use moisturizers whenever possible
There's no such thing as over moisturizing if you're using the right product. You know your body the best - if it feels right to apply gobs of thick, luxurious formulas to your body, then that's what should be done. However, be cautious of how the creams might be affecting your pores. Your skin needs to breathe, and while some moisturizers might be good for immediate relief, if you notice that they're sitting on top of your skin without absorbing, it might be because an ingredient in the formula is preventing your body from soaking it in as quickly as you're applying it.
When you've figured out how often you should reapply, it's time to consider if a formulated product is the next step. The Elemis Pro-Collagen Radiantly Smooth Body Cream 50ml, for instance, gives your skin the moisture boost it needs and helps support firmness.
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Owain Rowlands has recently come into the county to further his weightlifting education at Strength Academy Wales, where he works as an instructor, and Bill Carne popped down to SAW to talk to the North Walian about his own weightlifting ambitions . . .
There is no doubt that one of the growth sports in Pembrokeshire is weightlifting as people of all ages have started to take a great interest in keeping fit and having regular work outs in the gym are very much order of the day.
Added to this involvement is the awakening in competitive weight lifting and 24 year-old Owain Rowlands is involved in both aspects because he works with weight-training at Strength Academy Wales and has made a good start to competing as his performance at the recent Welsh Closed Championships in Haverfordwest earned him qualification for the forthcoming Welsh Senior Championships at the Institute of Sport, Sophia Gardens, Cardiff.
Owain originally hails from Llangefni, on Anglesey, in North Wales but moved to Bridgend and then Pembrokeshire when he saw the advertisement for a full-time assistant coach at SAW and to his delight was offered the job by Simon Roach, who runs the SAW facility at STP School.
"Coming to Pembrokeshire was the best thing I have done," admitted Owain, "because Simon has made me very involved and also set me on the road to competing."
Yet rugby was Owain's main sport as a youngster as he played hooker for Llangefni up to the time when RGC was formed as the North Wales' representatives in Welsh Rugby's championship division. But then he tore his hamstring and sustained a couple of ankle injuries before his work as a carpenter took him to Bath.
It was there that he came across a cross-fit type of gym as he tried to regain full fitness and took to it straight away – and decided on a change of direction in work, taking up the chance of attending a course for gym instructors.
"After some work in Bridgend, I came here," said Owain, "and what I love is the wide range of work we do because as well as working with the public I also help Simon with the talented youngsters who come here as the Scarlet West Academy under 16s, the Pembrokeshire Schools and the under 18s who play in the. National College League.
"They have knuckled down to really hard work and improved their techniques and the weights they are lifting to help their upper body strength and general fitness.
"I also coach weightlifting at Pembroke School one lunchtime a week and will soon be involved in a similar way at Ysgol Bro Gwaun in their 5x60 after school sporting set-up.
Then there's the power lifters and complete novices who want to get fitter – and there is a great camaraderie here that I really enjoy."
It was after chatting to Simon about his boss's competitive weight lifting that Owain decided to give the sport a try and after polishing up his 'snatch' and 'clean and jerk' techniques he was given his first taste of competition at a local event organised by Pontypool Willpower Club where he was allowed to take part.
"Simon came along for company," Owain told us, "and it was the most nervous I had ever been in my life.
"I learned a real lesson that day – lifting is dependent on the state of mind as well as the actual physical involvement. I only managed three clean lifts out of six attempts in the 85kgs class and I suppose overall I was satisfied with my 90kgs in the 'snatch' and 110kgs in the 'clean and jerk' which gave me a combined total of 200kgs."
Owain worked hard for the Welsh Closed as he went back to North Wales for Christmas.
"I only had Christmas Eve, Christmas Day and Boxing Day off from practice," he said with a chuckle, "and that was only because there were no gyms open!"
He has also worked hard with Simon on his build-up to the lifts and tried to shut out the fact that he was being watched by lots of people, focussing on the bar and getting a job well done. He also dropped down a class to the 77kgs category and still managed to improve his combined total by 16gs as he lifted 96kgs in the 'snatch' and 120kgs in the 'clean and jerk'.
"I only just missed out on 125kgs for the latter but I was pleased by the fact that I managed 13kgs over the qualifying weight for the Welsh Senior Championships."
Owain is delighted to see the newly-formed Pembrokeshire Weightlifting Club really taking off, especially the fact that youngsters are beginning to take part, because they are the future of weight lifting in the county. Justin Head has also started out with a club in Pembroke and Steve James is looking to build numbers in Milford Haven under the watchful eye of Simon Roach, who is now the performance director at the Welsh Weight Lifting Association.
"We are delighted that parents are becoming aware of the good that can be done by youngsters in our sport," said Owain, "not only in terms of a healthy regime but with regard to an awareness of the need for sensible diet and self discipline in and out of the gym."
Owain has clearly embraced all that is good in the sport and his ambition is to make it into the Welsh Development squad, which trains at Sophia Gardens and has other training camps during the year. No-one is more delighted at the progress he has made than Simon Roach, who told us:
"Owain is an asset at SAW with his genuine enthusiasm, reliability and willingness to learn. He has quickly built up a rapport with customers, the rugby lads and in schools – and as he grows in confidence as a competitor he is going to do well."
High praise indeed from someone who knows his weightlifting onions and we could pay Owain Rowlands no higher compliment – and we wish this modest and unassuming young man continued success in his chosen sport!


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Turn any refractor or Maksutov-Cassegrain telescope into a high-performance spotting scope! Install our high-quality Deluxe 45° Correct-Image Prism Diagonal in a telescope to have it transmit a view that's right-side-up and correct left-to-right for optimized daytime viewing performance.
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Limited Warranty against defects in materials or workmanship for one year from date of purchase. This warranty is for the benefit of the original retail purchaser only. For complete warranty details contact us at 800-676-1343.
Please note this product was not designed or intended by the manufacturer for use by a child 12 years of age or younger.
Binocular lenses and prisms are often coated with anti-reflective material to minimize light loss as light travels through the multiple optical surfaces of a typical binocular. Coatings help maximize the amount of light transmitted through each glass surface of a binocular, so as much light as possible reaches the observer's eyes to provide a bright and sharp image.
Good lenses are at least "fully coated," with a single layer of magnesium fluoride coating applied to each air-to-glass lens surface. Multiple layers of coatings are even more effective; the term "multi-coated" means one or more air-to-glass lens surface has multiple coatings. "Fully multi-coated" optics are even better, meaning all lens surfaces have multiple layers of anti-reflective coatings applied for maximum light transmission and optimal image quality.
Orders received by 1pm Eastern Standard Time for in-stock item the same business day. Order received after noon will ship the next business day. When an item is not in-stock we will ship it as soon as it becomes available. Typically in-stock items will ship first and backordered items will follow as soon as they are available. You have the option in check out to request that your order ship complete, if you'd prefer.
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Online or in your mailbox. Check out our colorful catalog, filled with hundreds of quality products.
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Alright, I just got some new discs that I really like, but I only really want to carry around 4 or 5 discs with me. I'm an intermediate player if that helps. Here's what I've got:
Star Destroyer
Archangel (probably ditching this)
DX Wraith
Champion Orc
Champion Eagle
Champion Teebird
"Special Edition" Teebird (looks kind of like this: http://www.ironliondgs.com/images/P2260004.JPG, any info you can give me on it would be awesome)
DX Cobra
Discraft Magnet


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Pelfrey has elbow surgery, to miss at least two months
TORONTO -- Right-hander Mike Pelfrey underwent surgery on Tuesday to clean up scar tissue in his right elbow that was causing pressure on his ulnar nerve, the Twins announced.
Pelfrey met with Dr. James Andrews for a second opinion on his elbow in Pensacola, Fla., on Monday, and Dr. Andrews performed the surgery on Tuesday. He's expected to be out two to four months.
Pelfrey had Tommy John surgery on his right elbow on May 1, 2012, which caused him to miss the rest of that season and led to the scar tissue buildup in his elbow that necessitated Tuesday's operation. But his ulnar collateral ligament is fine now, as the injury was related to the ulnar nerve.
Pelfrey began to feel numbness in his fingers during Spring Training but never notified the training staff, as it was something he'd dealt with earlier in his career without any issues.
He went on to post a 7.99 ERA in five starts with diminished velocity before going on the 15-day disabled list with a groin strain on May 2. He made two rehab starts with Triple-A Rochester before he began to feel what he thought was shoulder pain, but turned out to be related to the ulnar nerve in his elbow after he had both his shoulder and elbow checked out by Twins doctors in late May.
Pelfrey, 30, posted a 5.19 ERA in 29 starts in his return from Tommy John surgery last year, and the Twins were hopeful he'd bounce back this season after being another year removed from the surgery. He signed a two-year, $11 million deal in the offseason to remain in Minnesota.
Rhett Bollinger is a reporter for MLB.com. Read his blog, Bollinger Beat, and follow him on Twitter @RhettBollinger. This story was not subject to the approval of Major League Baseball or its clubs.


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Topic: 3-year scan results!!
Hello all of my supportive friends!
Had the appointment with my oncologist today to go over my scan results and he said that everything looked good, that at the 3 year mark with no recurrence he feels pretty good about my long term prognosis!!!
He also said that I don't have to come back for another scan for 6 months and that he would only recommend 3 more followup scans if they are all clear. All of this sounds both wonderful and scary to me.
I feel so blessed and I just wish everyone on here could be as blessed as I am and they would find a cure for this horrible disease.
Thank you for all of your support!
My comments, suggestions, and opinions are based only on my personal experience as a cancer survivor. Please consult a physician for professional guidance.


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HOPKINTON, Mass., Jan. 8, 2013 /PRNewswire/ -- EMC Corporation (NYSE: EMC) today announced that Sanofi Pasteur, a world leading vaccine manufacturer producing more than 1 billion doses of vaccine per year, has deployed EMC® Documentum® D2, enabling the company to accelerate time-to-value through the power of configuration. Documentum D2 is a content management application with a modern, configurable and intuitive user experience for the EMC® Documentum® platform, and a key component of the Documentum for Life Sciences solution. This solution has enabled Sanofi Pasteur to transform business, and modernize its content management system into a unified, document control and compliance infrastructure for managing mission-critical regulated content.
Customer Benefits of the EMC Documentum Life Sciences Solution:
Sanofi Pasteur offers a broad range of vaccines protecting against 20 infectious diseases across 12 globally dispersed production sites, requiring compliance with local and international quality and regulatory procedures.
Sanofi Pasteur turned to EMC to gain document control and provide a common framework enabling secure collaboration, efficient audit management, and scalability across its global operations. Working with the EMC Information Intelligence Group's Services organization, Sanofi established an enterprise-wide Global Electronic Document Management Policy to ensure process quality, consistency and control across document lifecycles while corresponding to GxP standards.
This approach enabled Sanofi Pasteur to extend its document management strategy and support electronic Trial Master Files (eTMF) in compliance with good clinical practices and applicable regulatory requirements for greater clinical efficiency, real-time access and collaboration with regional sites and CROs.
Customer Quote:
Alain Delpuech, VP Information Solutions, Sanofi Pasteur
"Sanofi Pasteur is committed to delivering superior, innovative vaccines for the prevention and treatment of disease. By standardizing on the Documentum Life Sciences solution, we're able to provide a unified document control foundation for compliance that spans across the vaccine development lifecycle and extended enterprise. This helps us ensure process quality, reduce risk and drive innovation to keep our business highly competitive."
About EMC Documentum for Life Sciences
EMC's Documentum-based Life Sciences solutions deliver a unified, configurable document control platform for compliance with industry regulations. The foundation of these solutions include the Documentum Enterprise Content Management platform, Documentum D2 for configuration and intuitive user interfaces, implementation and migration services. The D2 configuration technology enables auditing, reporting and e-signature support for compliance, lifecycle management and document control services, and industry-specific modeling capabilities all designed for Life Sciences.
About EMC Documentum D2
Documentum D2 simplifies the user experience for Documentum and enhances the productivity of knowledge workers by easily tailoring their user experience for their specific requirements. It accelerates time-to-value through the power of configuration for building and delivering content centric solutions to meet the needs of the business. In addition, administrators now have consistency of ECM rules and policies through this simplified information management approach based on configuration.
Additional Resources:
About EMC
EMC Corporation is a global leader in enabling businesses and service providers to transform their operations and deliver IT as a service. Fundamental to this transformation is cloud computing. Through innovative products and services, EMC accelerates the journey to cloud computing, helping IT departments to store, manage, protect and analyze their most valuable asset information in a more agile, trusted and cost-efficient way. Additional information about EMC can be found at www.EMC.com.
EMC and Documentum are registered trademarks or trademarks of EMC Corporation in the United States and other countries. All other trademarks herein are the property of their respective holders.
SOURCE EMC Corporation


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Mosso Press Release
The Rackspace Cloud Goes Open Source with APIs
Company Fostering Foundation for Open Clouds and Cross Cloud Interoperability; Empowers Cloud Development Community
SAN ANTONIO–(BUSINESS WIRE)–In a major advancement of its open cloud strategy, Rackspace® Hosting (NYSE:RAX), the world's leader in hosting, today announced it has open sourced the specifications for its Cloud Servers and Cloud Files™ APIs under the Creative Commons 3.0 Attribution license. Developers are now free to copy, implement, and modify the specifications, helping to enable a truly open cloud.
The Rackspace Cloud™ worked directly with developers in an open community to create the specifications and has now released them through Creative Commons. Creative Commons is a not-for-profit organization, founded in 2001, that promotes the creative re-use of intellectual and artistic works, whether owned or in the public domain through its free copyright licenses.
"We welcome Rackspace's decision to provide their client-side tools as open source to the community," stated Rich Wolski, Chief Technology Officer, Eucalyptus Systems Inc. "It builds confidence among developers to know they can 'see' how the APIs function at a programmatic level. Moreover, by providing their API tools as open source, Rackspace is assuming a leadership position in helping to achieve cloud interoperability."
As part of its ongoing vision to open the cloud and speed cloud development, the company has also made available its Cloud Files language bindings for Java, PHP, Python, C#, and Ruby under the MIT license. The source code for these bindings is publicly available on GitHub, a public software versioning system, at http://github.com/rackspace, where external developers can now contribute. Rackspace has also produced a technical guideline for Cloud Servers language bindings which is also available on GitHub. This guideline will enable developers to build Cloud Servers bindings in a variety of languages, but with a consistent design and feel. Rackspace expects to offer a reference implementation in Python soon and is aware of Ruby, Perl, Java, and Twisted Python Cloud Servers bindings that are in the process of being developed.
Rackspace's commitment to openness extends to its work with the community and expects to continue to expand the range of language bindings as developers provide them and work with developers to help ensure they are notified quickly of new features and updated technical specifications.
"It's great to see Rackspace push the movement forward by getting more code into the hands of the community," stated, Alex Polvi, CEO, Cloudkick, a leading cloud management platform developer. "We are thrilled to see the company moving so quickly and proactively to promote an open cloud."
"Rackspace is committed to the development of open cloud solutions and standards. We are working quickly to offer a wide range of tools to help developers work with us to create these important building blocks for the cloud industry," said Emil Sayegh, General Manager, The Rackspace Cloud. "Rackspace is dedicated to bringing a coordinated effort to cloud development. We are working directly with our ecosystem of developers and the broader industry to share what we create with the open source community. We believe open source APIs are an enabling factor in making interoperable non-proprietary cloud solutions a reality."
About The Rackspace Cloud
The Rackspace Cloud provides on-demand scalable website, application and storage hosting backed by Fanatical Support®. Through its suite of cloud solutions, Cloud Sites™, Cloud Files™ and Cloud Servers™, The Rackspace Cloud enables astute developers and IT managers to minimize the hassles, upfront investments and high costs associated with dedicated hardware, while offering the ability to easily scale hosting resources. For more information about The Rackspace Cloud, visit www.rackspacecloud.com or call 1-877-934-0409.
About Rackspace Hosting
As the leader and specialist in hosting services, Rackspace® Hosting is changing the way businesses worldwide buy IT. Rackspace delivers computing-as-a-service, integrating the industry's best technologies into a flexible service offering, making computing more reliable and affordable. A trusted partner to companies of all sizes, Rackspace enables IT departments to be more effective. Rackspace is distinguished by its award-winning Fanatical Support®, furthering the company's mission to be one of the world's greatest service companies. Rackspace is recognized as one of FORTUNE Magazine's 100 Best companies to work for in the US, ranking number 43 on the list. Rackspace's portfolio of hosted IT services includes Managed Hosting, Cloud Hosting, and Email and Apps. For more information on Rackspace Hosting, please visit www.rackspace.com.
Forward Looking Statements
This press release contains forward-looking statements that involve risks, uncertainties and assumptions. If such risks or uncertainties materialize or such assumptions prove incorrect, the results of Rackspace Hosting could differ materially from those expressed or implied by such forward-looking statements and assumptions. All statements other than statements of historical fact are statements that could be deemed forward-looking statements, including any statements concerning expected development, performance or market acceptance associated with our Cloud Hosting products, including Cloud Sites and Cloud Files, or acceptance or use of our Cloud Servers API; anticipated operational and financial benefits from our Cloud Hosting products and services or from further use and development of our Cloud Servers API; any statements of expectation or belief; and any statements of assumptions underlying any of the foregoing. Risks, uncertainties and assumptions include the possibility that benefits from our Cloud Hosting products, including Cloud Sites and Cloud Files, may not materialize, due to a number of reasons including (i) a failure of the products to attain adequate reliability, quality or compatibility, (ii) changes in technology which adversely affect the benefit of the products, (iii) general economy or technology industry downturns, (iv) internal strategy decisions that negatively impact the progression or development of the products, and (v), and other risks that are described in Rackspace Hosting's Form 10-Q for the quarter ended March 31, 2009, filed with the SEC on May 12, 2009. Except as required by law, Rackspace Hosting assumes no obligation to update these forward-looking statements publicly, or to update the reasons actual results could differ materially from those anticipated in these forward-looking statements, even if new information becomes available in the future.


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NVIDIA confirmed in a blog post this morning that SHIELD will be available on June 27th at a price of $299. When it was first announced the price point was $349, so this is a $50 reduction on the Android powered 5-inch screened gaming device. If you've already pre-ordered SHIELD don't freak out, you'll be charged the new, lower price. NVIDIA stated that the change was made after the company received feedback from thousands of gamers that if SHIELD was $299, we'd have a home run on our hands after being announced for pre-order back in May. Now that the NVIDIA SHIELD is priced at $299 will it be something you'd purchase?
SHIELD is the one device that taps into the planet's largest ecosystem of games — spanning NVIDIA TegraZone, Google Play and Steam. Rediscover your Android games with the mobility, control and performance of SHIELD. Connect to your Google Play account to enjoy your favorite movies, music and apps.
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