text:
In July, MasterCard ( MA), Visa ( V) and other major banks agreed to pay more than $6 billion to resolve accusations that they engaged in anti-competitive practices and price fixing in payment processing. In addition, credit card companies agreed to reduce swipe fees for eight months, an adjustment valued at $1.2 billion. The settlement would also allow retailers to charge higher prices to their customers for paying with credit cards. Before this settlement, the card companies prohibited retailers from adding this type of surcharge. Just days after the proposed settlement, Wal-Mart ( WMT) and Target ( TGT) came out against it and were joined by major trade groups including the National Association of Convenience Stores, the National Retail Federation and the National Restaurant Association. Eventually, a majority of the original 19 plaintiffs would come out against the settlement. They are challenging a part of the order that would free Visa and MasterCard from new legal claims over related interchange issues. The settlement got initial approval in the U.S. District Court in November but is being appealed in the appeals court. 2. Growth of prepaid cards
Thanks to regulations and legislation on credit cards, banks are turning renewed attention to prepaid cards. Prepaid cards have fewer regulations than credit cards and banks are embracing prepaid cards for needed revenue. Today, competition for the prepaid market is growing and driving down rates and fees. Consumers loaded approximately $57 billion onto prepaid cards in 2011, and loads were projected to reach approximately $82 billion last year, $117 billion this year and $167 billion next year, according to the Mercator Advisory Group. There are no government regulations and consumer protections on prepaid cards -- debit and credit card rules and regulations do not apply. But that may soon change. The Consumer Financial Protection Bureau is investigating the fees and practices of prepaid cards and seeking input on ways to enforce safety for consumers.


text:
Get the Cheapest Internet in GeorgiaCheap Internet > Georgia > M
Cheap Internet is easy to come by, but only if you know where to look. Fortunately you've found one of the best resources for finding Internet deals in Georgia. Whether you're upgrading from slow dialup or satellite Internet service, or you're trying to save a few dollars over expensive cable Internet, Georgia DSL is a great option.
With DSL, you get the benefit of high-speed Internet, without the cost of cable or satellite. On top of that, you get a dedicated and always-on connection to the provider, making it one of the most secure connections possible. If you're ready to find the cheapest Internet for your home, click through to your city below.
Not sure if DSL is for you?
No problem! By calling the number on this screen, you'll be connected with an industry leading Internet expert. He or she will be able to guide you to all of the best deals on high speed Internet service. Not sure which service will be best for you? Our experts have the tools that will give you the answers to all of your Internet questions.

subset: commoncrawl


text:
A multiplatform C++ library for dynamic generation of Excel .xls files containing multiple worksheets. Unlike .csv files, these can be directly opened by Excel and thus provide an excellent way to output large data sets that require further analysis.
To see the latest changes, select "Files" and view the README text displayed at the bottom of that pane.
IMPORTANT: Major changes are contained in the current SVN source. If you have time please try to use it or the xlslib-package-2.4.0b1.zip archive, and enter bug reports on any problems!
- library specific strings now in their own namespace
- iOS Objective-C library
- most project files updated (MSVS etc)
- C bridge now supports formulas
Note: there is a related SF project, libxls, to read Excel files.
- MS Visual Studio 2005 - 2012 / CodeBlocks / RadStudio / BDS Projects
- "C" Bridge (now supporting Formulas)
- Objective-C Interface for OSX and iOS (iOS NEW!)
Other Useful Business Software
User Ratings
User Reviews
I can't rate it as of now as I am yet to understand the way to use it. I saw some posts saying "the test folder has some usage examples", but I have not seen any test folder in the library. It will be a great help if some one tells me how to use the library for writing simple xls file from a C++ project. IN any case I can only be thankful to the creators of this liabrary for making it available for developers like me.
Can't uderstand, how to include the library to my project. Can anyone help me with details (I am a beginner)?
it is a usefull lib. but i have a problem,list is my code void test(void) { workbook swb; xf_t* sxf1 = swb.xformat(); worksheet* ssh; ssh = swb.sheet("sheet_1"); string snamelabel = "中文"; ssh->label(1,2,snamelabel,sxf1); swb.Dump("workbook.xls"); } create the workbook.xls exactly, but the cell value is "iconv failed!". it is convert error, so what should i do,this is a matter of great urgency for me,who can help me ,thanks!
This is a great lib. Thank you!!!
Great lib. But I have a SIGABRT when compiling in release mode in XCode for iOS. I found that the problem in the Optimization Level setting. I changed it from -Os to -O3 so problem disappeared. Can you look at it when you have time?


text:
Soon-to-be-pro basketball star Anthony Davis (pictured) is raising eyebrows with his unique marketing campaign.
The University of Kentucky stud, and expected No. 1 pick in tonights NBA draft, has applied for trademark rights to Fear the Brow and Raise the Brow, in hopes of profiting from his odd facial trait.
I dont want anyone to try to grow a unibrow because of me and then try to make money off of it, Davis told CNBC. Me and my family decided to trademark it because its very unique.
Davis applied to trademark both phrases this month.
But a Lexington, Ky., T-shirt maker, Blue Zone LLC, put in a claim for Fear The Brow last November, records show. The companys owner claims hell have exclusive rights to the slogan.
We came up with Fear the Brow, said owner Reid Coffman. Fear the Brow wasnt even a thought until October of last year, until he started playing. We came up with it.


text:
Note: This item is more than 12 years old. Please take the publication date into consideration for any date references.
Print – Plain Text – Permalink
News Release
Media Contact: TPWD News, email@example.com, 512-389-8030
Jan. 31, 2005
Redfish Bay Scientific Area Extension Proposed
ROCKPORT, Texas — The Texas Parks and Wildlife Department is planning a new approach to protect ecologically important seagrass beds in coastal bays from propeller-scarring by recreational boats. Scientists believe this propeller scaring is causing long-term damage in some areas.
"We're going to be seeking input from anglers, fishing guides, conservation organizations and others to develop a coast-wide approach to protect shallow-water seagrass in areas of high boat traffic," said Larry McKinney, Ph.D., and TPWD coastal fisheries director.
"We want to continue to emphasize boater and angler education to encourage voluntary seagrass conservation along the entire coast and generally get away from focusing on special areas. We will make use of our existing Seagrass Conservation Task Force and focus our activities in the Redfish Bay Scientific Area."
McKinney said the department is proposing to continue the Redfish Bay scientific area through 2010 and will be working with the task force in the spring to come up with any specific actions or changes to afford greater seagrass protection in the scientific area.
The department is not proposing to continue the Nine Mile Hole Scientific Area, mainly because it is located in a remote region and TPWD lacks the resources to properly monitor and study the area. McKinney emphasized that fisheries biologists are still talking with local groups to get their ideas on the future of Nine Mile Hole.
McKinney said the department prefers an approach that will focus on reducing direct impacts that destroy seagrass root structure and substrate (bay bottom) integrity. Evidence shows that these actions reduce the likelihood of seagrass recovery in areas where the bay bottom is scarred by motorboat propellers.
The current extension of the Redfish Bay Scientific area is being proposed as part of a legislatively-mandated rule review and is packaged with several other cleanup items in department regulations regarding fisheries. The proposed regulatory changes that would take effect sometime around June, if adopted. The department will publish proposals in the Texas Register and hold public meetings to solicit input before the TPW Commission votes to finalize these proposals at its April 7 meeting. Subsequent proposals dealing with seagrass will probably come in early summer, depending on the work and the progress of the department working with the task force.
Shallow-water seagrasses in Texas bays provide vital nursery areas for diverse marine life, food and cover for game fish, bottom stabilization, and better water quality. Seagrass has declined in many areas on the Texas coast. In Galveston Bay, 95 percent of all seagrass has disappeared. In the Redfish Bay area, the total acreage of seagrass has declined by 13 percent since 1958. The area marks the northernmost extent of one important species commonly known as turtlegrass. This species is particularly susceptible to propeller damage because of the long recovery time when damaged.
In 2000, a Seagrass Conservation Task Force made up of commercial and recreational anglers, local governments, homeowners, fishing guides, boat dealers and other business owners unanimously supported a plan to create restrictions on boating at Redfish Bay and Nine Mile Hole in the Lower Laguna Madre.
A study done in the 1990s by the Corpus Christi National Estuary Program found seagrasses declining, changing or fragmenting in areas with high boat traffic. TPWD and the seagrass task force concluded that scars from boat propellers contribute substantially to seagrass fragmentation and loss and may worsen bottom erosion. Prop scars are more common near popular fishing areas.
Anyone may receive a copy of the proposed extension of the scientific area designation for Redfish Bay by sending a written request by e-mail to jerry.cooke @tpwd.texas.gov or by regular mail to Jerry Cooke, Texas Parks and Wildlife Department, 4200 Smith School Road, Austin, TX 78744. Anyone may comment about the proposed new rules by writing to the same addresses or by commenting online via the TPWD Web site.
On the Net:
Publication — Permission is granted to publish, in whole or in part, any news releases on this page.
Print — A print-friendly version of the news release shows only the release with font sizes set to the browser default.
Plain Text — Plain text versions of TPWD news releases are provided for copying and pasting into editing software.
To copy text into an editing software:
- Click a Plain Text link to display the plain text page in your browser.
- Select all.
- Copy.
- Paste in a document in your editing program.
Permalink — This is a direct link to the news release, omitting the navigation context from the URI.
English/Spanish — News releases posted in both English and Spanish have one of these links.
If you have any suggestions for improving these pages, send an e-mail to email@example.com and mention Plain Text Pages.
(5.4.16 i)


text:
About the Book
A reluctant groom . . .
Noble warrior James MacCarran has no desire to venture onto the thorny battlefield of marriage. But his grandmother's will issues an ultimatum—marry or forfeit his rightful inheritance—and now he must find a bride. Only the most ravishing woman could make it worth his while, but when he meets Elspeth MacArthur, she is nothing like he anticipated. Yes, she is beautiful, luminous really, but there is something mysterious about this lass . . . An enchanting bride . . .
Reluctant to leave her Highland home, Elspeth must keep an astonishing secret when unexpected circumstances force her to marry. But as an unseen threat draws ever closer, about to reveal the truth of her life in the mystical Highlands, she soon realizes that her only haven is in James' passionate embrace . . . and that carries the greatest risk of all.
Educator and Librarian Resources
Product Details
- Imprint: HarperCollins e-books
- On Sale: 10/13/2009
- Pages: 384
- List Price: 3.99 USD
- BISAC1: FICTION / Romance / Historical / General
- BISAC2: FICTION / Romance / General


text:
Toggle navigation
Place an ad
Sign in with Classifieds account
Sign in with Classifieds account
Place an ad
Search All Classifieds
Auctions / Sales
Business Services
Garage Sales
Pets & Animals
Real Estate
Find a job
Post a job
Find a car
Post a car
Hire Freelancers
Find Freelance Work
Featured Ads
CKC Malti-poo pups. 3 Females left! Tiny and going to be very tiny in size. Vet checked and shots up to date. Fluffy and sweet. Great home only, They just wants to snuggle. $500.00 606-674-3100 Will be ready to go soon! Rare spotted!
A+ BBB rating. 25 years in the painting/remodeling fields. It's all about attention to detail and doing the job right. Estimates are absolutely free. Call us today, we look forward to working for you.
Collie Puppies
Beautiful Collie puppies, AKC registered, UTD shots and wormings. These pups are outstanding normal eyed non carriers will never have eye problems. Mom and Dad are onsite. Will go to approved homes only with limited registration.
ADVERTISE! You can place your own Classified ad at http://lexingtonherald.adperfect.com
mini schnauzer pups
CKC Mini Schnauzers, Black and silvers all of them! I have 4 males , 1 female, Vet checked and up to date on shots and wormings! Ready for loving homes only!!! 606-674-3100 Pictures to follow. $450.00 males are not pictured yet because I have to get all groomed, same color!
Adopt for a GREAT PRICE &...
Adopt for a GREAT PRICE & Save a Life
Beautiful, Cuddly Cats, Kittens & Puppies!
Spayed & Neutered & Ready to Go Home!
Already Have Shots & Vaccines!
Adopt a Mutt with Manners:
AKC Chow Chow puppy
One red female chow chow puppy available. Born on 8-14-17. Puppy will come with full AKC registration and 1st shots.
Advertise here now
View all featured ads
Recent ads
INSTANT CASH paid for Gold, Silver, Coins,
Diamonds, Watches,
Jewelry, Pocket Watches, Baseball cards, Autographs, Game used items, Bats & Gloves, Trains, Comic Books, Antiques, Old Toys, Artifacts,...
SOLID WOOD bunk bed in...
SOLID WOOD bunk bed in original box $159.
A NEW memory foam mattress,...
A NEW memory foam mattress, in plastic, 10 yr. warranty. $149. 859-629-4954
Help center
Give us a call
Request Help


text:
Dr. Eric Mariotti is a board-certified plastic surgeon serving Walnut Creek, San Ramon, Danville, Concord and Bay Area patients. From a young age, Dr. Mariotti wanted to be a surgeon and fell in love with plastic surgery during his time in medical school. He attended Jefferson Medical College in Philadelphia where he received his Medical Degree and went on to complete residencies in General Surgery at the University of Connecticut, Farmington, CT, and in Plastic Surgery at the University of Louisville, Louisville, KY, where he later became Chief Resident. His passion for plastic surgery helps Walnut Creek, San Ramon and other Bay Area men and women achieve a satisfying look. His skill as a surgeon, and his down-to-earth, genuine attitude have earned him the respect of his peers and patients alike.
Dr. Mariotti practices all aspects of plastic surgery but has developed a specialization in aesthetic surgery of the breast and body. Approximately 50% of his practice encompasses breast surgery including breast augmentation, breast reduction, breast lifts with and without implants and breast reconstruction. Dr. Mariotti has created a niche in the Bay Area for post-weight-loss plastic surgery. He speaks regularly to local support groups, and has served the weight loss community for years.
Why Choose Dr. Mariotti
Dr. Mariotti has been in private practice since 1999 and has helped many men and women achieve their cosmetic enhancement goals since. As a board-certified plastic surgeon and a member of several national and state-level medical societies, he is a respected member of the medical community in addition to being a loving husband and father of three. His patients report that his approachable and compassionate attitude makes their plastic surgery experiences pleasant, enjoyable, and rewarding.
Beyond his work in the office, he has volunteered in several humanitarian programs designed to help those who may not have access to medical services. He has gone to the Philippines to operate on children with cleft lips and cleft palates, and has gone to Bhutan to assess patients' orthopedic concerns and to perform orthopedic operations. Additionally, he founded, organized and participated in a program which enabled medical students to work with doctors in Honduras, providing primary care to the indigent population.
For his outpatient procedures, Dr. Mariotti uses Premier Surgery Center in Concord, California. This accredited surgical center is conveniently located in the same building as Dr. Mariotti's own office.
If you are interested in meeting Dr. Mariotti to discuss your plastic surgery goals, you can request a consultation online at his website or by calling our Concord office. Your consultation is free of charge.
We accept Visa, MasterCard, cash, check, and cashier's checks. We also provide several financing plans to take the worry out of your experience. Insurance Consultations are billed to your insurance company.
Cosmetic Consultations are offered at No Charge
Insurance Consultations are billed to your insurance company
For his outpatient procedures, Dr. Mariotti uses Premier Surgery Center in Concord, California. This accredited surgical center is conveniently located in the same building as Dr. Mariotti's own office.
- University of Louisville, Kentucky - Plastic and Reconstructive Fellowship 1997 - 1999
- University of Connecticut 1993 - 1997 - General Surgery Residency
- Jefferson Medical College, 1989 - 1993. Rated #1 Medical School 1990-1992
- University of California Davis - 1989 Biological Sciences Degree
- American Board of Plastic Surgery 2000
- American Society of Plastic Surgeons
- American Society of Aesthetic Plastic Surgery
- Alameda Contra Costa County Medical Society
- California Society of Plastic Surgery
- John Muir Medical Center, Concord Campus
- John Muir Medical Center, Walnut Creek Campus
- Doctors Medical Center, San Pablo


text:
First US Airways did away with snacks, then they added a $15 fee to check a bag, and now they'll be charging $2 each for sodas, juices, bottled water and coffee in coach. Are you going to stand for this? Take our poll, inside.
New fee at US Airways: $2 soda [Philadelphia Inquirer]
(Photo: John Kit )


text:
kvanorsdel wrote:Bobby12many wrote:QUestion to you guys; Is Baraboo Lions DGC worth an exclusive 2 hour drive?
I'd say yes. I really like the barbaoo course. its rarely busy and by busy I mean 4 or 5 other groups on the course. Make sure you go when its not wet. The only downfall of the course is the rubber teepads that can get slippery if wet.
Im looking for a good day-trip for me and my buddy. We will be coming from the Delafield/Waukesha area up there to play.
Are there any other courses within 20-30 miles that are worth scopin out?


text: IL Bisonte® leather card wallet Item G0372 Color: CARAMEL Size: ONE SIZE All sizes are US sizes. ONE SIZE Size Charts Quantity: 1 2 3 4 5 6 7 8 9 Prices do not include taxes. Add to Bag Wishlist Add to Bag Add To Wishlist share: size & fit 4 2/5"L x 3 1/10"W. Product Details Made in Italy, this leather card wallet is as sturdy and elegant as the bison, the animal IL Bisonte takes its name from. Leather. Made in Italy. Select stores. Item G0372.


text:
As one of the administrators of this message board, it is somewhat common to find a new member has actually joined just to post spurious links; these spammers have no interest in the Titanic or her era, but are instead paid by Internet businesses for each web site they infest and for each post that they make.
Very often, I log on to discover that another member has flagged a spammer's post for immediate attention, and I wanted to say thank you to those of you who are vigilant and proactive.
If you notice a post from anyone that mentions goods and services for sale, or who have active links as a signature, please use the report feature on that post to flag it so that I or one of the other administrators or moderators can quickly find and remove not only that post, but to ban the spammer as well. Often, you will find that a section of a post from that thread has been copied in their reply, but no matter -- if the post contains spam, it will be removed.
Thanks for your help -- it is deeply appreciated.
Tim Trower
THSMB Admin Team member


text:
Dose-finding Study of GSK2248761 in Antiretroviral Therapy-experienced Subjects With NNRTI-resistant HIV Infection (SONNET)
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
|Infection, Human Immunodeficiency Virus
|Drug: GSK2248761 100 mg once daily Drug: GSK2248761 200 mg once daily Drug: Etravirine
|Phase 2
|Study Type:
|Study Design:
|Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
|Official Title:
|A Phase 2b Study to Select a Once Daily Oral Dose of GSK2248761 in HIV-1 Infected Antiretroviral Therapy Experienced Adults With Non-nucleoside Reverse Transcriptase Inhibitor (NNRTI) Resistance
- HIV-1 viral load [ Time Frame: Weeks 16, 24, and 48 ]
- Safety and Tolerability- Incidence of adverse events and laboratory abnormalities [ Time Frame: Weeks 16, 24 and 48 ]
- HIV Disease Progression [ Time Frame: through Week 48 ]
- Changes in Immunologic Function (CD4/CD8 cell counts) [ Time Frame: through Week 48 ]
- Changes in viral genotype and phenotype [ Time Frame: through Week 48 ]
- Changes in Laboratory Parameters [ Time Frame: through Week 48 ]
- Study discontinuation due to Adverse events [ Time Frame: through Week 48 ]
- Changes in ECG [ Time Frame: through Week 48 ]
- Pharmacokinetic profile of GSK2248761 [ Time Frame: through Week 24 ]
- Pharmacokinetic profile of darunavir and ritonavir in combination with GSK2248761 [ Time Frame: through Week 2 ]
|Study Start Date:
|October 2010
|Estimated Study Completion Date:
|December 2015
|Estimated Primary Completion Date:
|April 2012 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: GSK2248761 100mg OAD
In combination with darunavir/ritonavir BID and raltegravir BID
Drug: GSK2248761 100 mg once daily
1 100mg capsule OAD plus matching placebo
Experimental: GSK2248761 200mg OAD
In combination with darunavir/ritonavir BID and raltegravir BID
Drug: GSK2248761 200 mg once daily
2 100mg capsules OAD
Active Comparator: Etravirine
In combination with darunavir/ritonavir BID and raltegravir BID
Drug: Etravirine
2 100mg tablets twice daily
Detailed Description:
Study SGN113399 is a Phase 2b randomized, partially-blinded, multicenter, parallel-group, dose-ranging study to be conducted in HIV-1 infected ART-experienced adults with documented NNRTI resistance.
A minimum of 150 subjects will be randomized 1:1:1 to one of two GSK2248761 doses or a control regimen containing ETV (50 subjects per group); all subjects will also receive darunavir/ritonavir and raltegravir. The trial will be partially blinded, i.e. subjects receiving GSK2248761 and the investigators will be blinded to the dose they receive. Subjects will not be blinded to whether they receive GSK2248761 or ETV.
Randomization will be stratified by:
- HIV-1 VL at screening, <50,000 copies/mL or >/50,000 copies/mL, and
- Darunavir susceptibility (screening phenotype fold change <7 or >/7 to 20)
Background ART will be administered open-label.
The primary endpoint analysis will take place after all subjects have completed Week 16. An optimal dose of GSK2248761 will be determined by the Week 16 analysis; this dose selection will be confirmed using an analysis from all subjects following completion of Week 24. If there is a clear efficacy, safety or tolerability advantage driving dose selection for GSK2248761, then all subjects receiving the non-selected dose of GSK2248761 will be switched to the selected dose following dose confirmation, after all subjects have completed Week 24. If no differentiation of dose can be made based on objective measures of efficacy, safety or tolerability, then both doses will be continued through Week 48.
After Week 48, all subjects will be expected to obtain local access to all commercially available ART.
No regimen switches of either background ART (DRV/r and RAL) or test agent or control (GSK2248761 and ETV) are allowed during the 48 week period of the study.
Study Endpoints/Assessments Subjects will have assessments performed which will include baseline demographics, disease characteristics, pharmacogenetics (PGx) and safety (laboratory and clinical evaluations). On study safety, efficacy, virologic, immunologic, and PK evaluations will also be conducted.
The primary endpoint will be the proportion of subjects with HIV-1 RNA <50copies/mL at Week 16. Dose selection will be based primarily on antiviral activity and tolerability in conjunction with immunologic, safety, virologic resistance and PK measures. Data from the Week 24 analysis will be used to confirm dose selection.
ViiV Healthcare is the new sponsor of this study, and GlaxoSmithKline is in the process of updating systems to reflect the change in sponsorship
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- HIV-1 infected adults greater than or equal to 18 years of age. Females are eligible to enter and participate in the study if she is (1) non-childbearing potential, (2) child bearing potential with negative pregnancy test at screening and Day 1 and agrees to use protocol-specified methods of birth control while on study.
- HIV-1 infection with a screening plasma HIV-1 RNA greater than or equal to 400copies/mL
- Previously received or current treatment with antiretroviral therapy (HAART) for HIV-1 infection (patient may be off ART at time of screening)
- HIV-1 harboring NNRTI resistance by screening genotype (defined as the presence of at least 1 NNRTI resistance-associated mutations)
Exclusion Criteria:
- Any pre-existing physical or mental condition (including substance abuse disorder) which, in the opinion of the Investigator, may interfere with the subject's ability to comply with the dosing schedule and/or protocol evaluations or which may compromise the safety of the subject
- Any condition which, in the opinion of the Investigator, may interfere with the absorption, distribution, metabolism or excretion of the drug or render the subject unable to take oral medication
- Women who are currently breastfeeding
- Any evidence of an active Centers for Disease and Prevention Control (CDC) Category C disease [CDC, 1993], except cutaneous Kaposi's sarcoma not requiring systemic therapy
- History of ongoing or clinically relevant hepatitis within the previous 6 months, including chronic hepatitis B virus (HBV) infection (HBsAg positive). Asymptomatic individuals with chronic hepatitis C virus (HCV) infection will not be excluded, however Investigators must carefully assess if therapy specific for HCV infection is required; subjects who are anticipated to require such therapy during the randomized portion of the study must be excluded
- History of liver cirrhosis with or without hepatitis viral co-infection
- Ongoing or clinically relevant pancreatitis
- History of the following cardiac diseases: myocardial infarction, congestive heart failure, documented hypertrophic cardiomyopathy, sustained ventricular tachycardia
- Personal or known family history of prolonged QT syndrome
- History or presence of allergy or intolerance to the study drugs or their components, or a history of drug or other allergy that, in the opinion of the Principal Investigator, contraindicates their participation. In addition, if heparin is used during PK sampling, subjects with a history of sensitivity to heparin or heparin-induced thrombocytopenia should not be enrolled
- HIV-1 genotype results with any of the following will be excluded: (1)Any screening genotype with virus showing a Y181 mutation in combination with any other NNRTI resistance-associated mutations, (2) Any screening genotype with virus showing a Y181I or Y188L alone or in combination with any other NNRTI resistance-associated mutations
- HIV-1 phenotype results with any of the following will be excluded: (1) Any screening phenotype with virus showing etravirine fold change >10, (2) Any screening phenotype with virus showing darunavir fold change > 20, (3) Any screening phenotype with virus showing raltegravir fold change >1.5
- Any acute laboratory abnormality at screening, which, in the opinion of the Investigator, would preclude the subject's participation in the study of an investigational compound. Any verified Grade 4 laboratory abnormality at screening would exclude a subject from study participation unless the Investigator can provide a compelling explanation for the laboratory result(s) and has the assent of the medical monitor
- Any of the following laboratory values at screening: (1) Creatinine clearance <50 mL/min via Cockroft-Gault method, (2) Alanine aminotransferase (ALT) greater than or equal to 5 times ULN. Subjects with ALT >2xULN but <5xULN may participate in the study, if in the opinion of the Investigator and GSK medical monitor the lab abnormality will not interfere with the study procedures or compromise subject safety, (3) Alanine aminotransferase (ALT) greater than or equal to 3xULN and bilirubin greater than or equal to 1.5xULN (with >35% direct bilirubin
- Any clinically significant finding on screening electrocardiograph (ECG), specifically (a single repeat is allowed to determine eligibility): (1) Heart rate <45 and >100bpm (males), <50 and >100bpm (females); Note: A heart rate from 100 to 110 BPM can be rechecked within 30 minutes to verify eligibility, (2) QRS duration >120msec, (3) QTc interval >450msec, (4) Non-sustained (greater than or equal to 3 consecutive beats) or sustained ventricular tachycardia, (5) Sinus pauses >2.5 seconds, (6) 2nd degree (Type II) or higher AV (Atrioventricular) block, (7) Evidence of WPW (Wolff-Parkinson-White) syndrome (ventricular preexcitation), (8) Pathologic Q waves (defined as Q wave >40msec OR depth >0.4 mV, (9) Any other abnormality which in the opinion of the investigator would interfere with the safety of the subject
- Treatment with any of the following agents within 28 days prior to screening, or has an anticipated need for these agents during the study: (1) radiation therapy or cytotoxic chemotherapeutic agents, (2) immunomodulators (such as systemic corticosteroids, interleukins, or interferons); Note: Subjects using short-term (<7 day) steroid tapers and inhaled corticosteroids are eligible for enrollment, (3) Any non-protocol-specified agent with documented activity against HIV-1 in vitro
- Treatment with an HIV-1 immunotherapeutic vaccine within 90 days prior to screening
- Receipt of an experimental drug and/or vaccine within 28 days or 5 half-lives, or twice the duration of the biological effect of the experimental drug or vaccine, whichever is longer, prior to screening
- Immunization within 28 days prior to first dose of IP
Please refer to this study by its ClinicalTrials.gov identifier: NCT01199731
Show 31 Study Locations
|Study Director:
|GSK Clinical Trials
|ViiV Healthcare
|Responsible Party:
|ViiV Healthcare
|ClinicalTrials.gov Identifier:
|NCT01199731 History of Changes
|Other Study ID Numbers:
|Study First Received:
|September 9, 2010
|Last Updated:
|April 19, 2012
Keywords provided by ViiV Healthcare:
HIV Infection
Additional relevant MeSH terms:
HIV Infections
Acquired Immunodeficiency Syndrome
Communicable Diseases
Immunologic Deficiency Syndromes
Lentivirus Infections
Retroviridae Infections
RNA Virus Infections
Virus Diseases
Sexually Transmitted Diseases, Viral
Sexually Transmitted Diseases
Immune System Diseases
Slow Virus Diseases
Raltegravir Potassium
Reverse Transcriptase Inhibitors
HIV Protease Inhibitors
Protease Inhibitors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Anti-HIV Agents
Anti-Retroviral Agents
Antiviral Agents
Anti-Infective Agents
Cytochrome P-450 CYP3A Inhibitors
Cytochrome P-450 Enzyme Inhibitors
HIV Integrase Inhibitors
Integrase Inhibitors
ClinicalTrials.gov processed this record on September 21, 2017


text:
SynapDx Autism Gene Expression Analysis Study (STORY) (STORY)
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
This study will prospectively enroll approximately 880 children, at least 18 months and less than 60 months of age, who have been referred to a pediatric developmental evaluation center. Enrolled children will have blood drawn for RNA gene expression analysis and optionally for metabolite, lipid and DNA analysis and undergo a clinical evaluation to determine the presence or absence of a diagnosis of ASD.
The primary objective of this study is:
- To develop an algorithm to classify blood RNA gene expression patterns to maximize agreement between the classification and a clinical assessment of presence or absence of Autism Spectrum Disorders (ASD).
The secondary objectives of this study are:
- To develop an algorithm to classify plasma metabolite and/or lipid profiles in such a way as to maximize agreement between the classification and a clinical assessment of presence or absence of ASD.
- To prospectively assess the clinical sensitivity and specificity of the plasma metabolite and/or lipid profile classification algorithm in a separate population consisting of children referred to a developmental evaluation clinic for a possible developmental disorder (DD).
- To evaluate clinical sensitivity and specificity of various combinations of gene expression signature, metabolite and/or lipid signatures, and presence of ASD-associated genetic variation detected by chromosomal microarray analysis (CMA) or sequencing protein-coding regions of the genome.
|Study Type:
|Study Design:
|Observational Model: Cohort
Time Perspective: Prospective
|Official Title:
|SynapDx Autism Spectrum Disorder Gene Expression Analysis Study
- RNA gene expression in peripheral blood [ Time Frame: Within 30 days of collection ]
- Metabolites, lipids and DNA variation in peripheral blood [ Time Frame: Within 30 days of collection ]
Biospecimen Retention: Samples With DNA
|Estimated Enrollment:
|Study Start Date:
|March 2013
|Study Completion Date:
|December 2014
|Primary Completion Date:
|July 2014 (Final data collection date for primary outcome measure)
Development Group
In the Development Phase, analyses will be performed until the classification algorithm is finalized.
Validation Group
The Validation Phase will assess the performance of the finalized classification algorithm in 300 subjects.
Detailed Description:
The primary aim of this study is to define a gene expression signature indicative of ASD and to establish its clinical sensitivity and specificity. Clinician diagnosis of ASD will be made using DSM-5 as the reference standard instrument. The widely used diagnostic instrument Autism Diagnostic Observation Schedule (ADOS-2) is a typical component of the clinical assessment for a child diagnosed with ASD and this evaluation will be performed on all study participants. Secondary aims of this study are (1) to define metabolite and lipid signatures indicative of ASD and establish their clinical sensitivity and specificity and (2) to determine clinical sensitivity and specificity of various combinations of gene expression signature, metabolite and/or lipid signatures, and presence of ASD-associated genetic variation detected by CMA and sequencing protein-coding regions of the genome
Analyses: Details of the analysis will be specified in a Statistical Analysis Plan (SAP), which will include procedures for handling outliers, missing data, and differences across sites. The SAP will be reviewed and approved by a committee of Principal Investigators (PIs) before unblinding of the validation set.
Primary analyses: The primary outcomes of the study will be the estimates of the clinical sensitivity and specificity of the SDX-002 test to classify subjects according to DSM-5 ASD diagnosis, with associated 95% confidence intervals. Sensitivity and specificity will be assessed on the Validation Phase population based on agreement with the clinical diagnosis of presence or absence of Autism Spectrum Disorder by DSM-5 (published May 2013).
The gene expression signature will be trained on the 500 subject Development Phase set, using 5-fold cross validation over the results of several machine learning algorithms, including partial least squares, support vector machines, and boosted decision trees. The training procedure will generate estimated ROC curves for each method, as well as confidence intervals for the area under the curve (AUC). The final choice of a machine-learning algorithm will be based on AUC, as well as on the estimated performance at the chosen operating point on the ROC curve. The operating point will be chosen to provide high sensitivity at an acceptable specificity.
Secondary analyses: In the majority of patients enrolled to date, consent was obtained for collection of an optional bio-repository sample. The intended analysis of the bio-repository samples has now been established (see also, secondary objectives listed above). The metabolomic and lipomic signatures will be similarly assessed on the subset of the 500 subjects in the Development Phase set who consent to a bio-repository sample. In addition to the gene expression signature, metabolite and/or lipid signatures and DNA analysis will be combined with the gene expression signature in various configurations and the impact of these additional measures on clinical sensitivity and specificity will be evaluated. If these additional metabolomic/lipomic signatures and/or DNA analyses improve test performance, these elements may be included in the SDX-002 assay.
Sensitivity and specificity the final SDX-002 assay will also be assessed among subpopulations using demographic information and the results of developmental testing. There are likely to be few subjects in many of these subpopulations and caution will be used in interpreting the results. Planned subpopulation analyses include gender, age, ethnicity, ASD DSM-IV-TR diagnostic subcategory, DSM-5 ASD severity level (social communication and restricted interests/repetitive behaviors) and ADOS-2 scores.
|Ages Eligible for Study:
|18 Months to 60 Months (Child)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
|Sampling Method:
|Probability Sample
Inclusion Criteria:
- Referred to a developmental evaluation center for evaluation of a possible developmental disorder, other than isolated motor problems.
- At least 18 months and less than 60 months.
- Parent/legal guardian has been informed about the study and has signed an informed consent form.
Exclusion Criteria:
- Prior reliable diagnosis of Autism Spectrum Disorder (i.e. prior evaluation by a multi-disciplinary team has already reliably established Autism Spectrum Disorder diagnosis).
- Unable or unwilling to complete study procedures.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01810341
Show 20 Study Locations
|Study Director:
|Barbara Rathmell, MD
|SynapDx Corp
|Responsible Party:
|ClinicalTrials.gov Identifier:
|NCT01810341 History of Changes
|Other Study ID Numbers:
|Study First Received:
|March 11, 2013
|Last Updated:
|December 15, 2014
Keywords provided by SynapDx:
Autism Spectrum Disorders
Gene expression
Developmental Delay
Additional relevant MeSH terms:
Autistic Disorder
Autism Spectrum Disorder
Child Development Disorders, Pervasive
Neurodevelopmental Disorders
Mental Disorders
ClinicalTrials.gov processed this record on September 19, 2017


text:
A 14-year-old boy from Trowbridge is in critical condition in hospital after suffering a cardiac arrest during a football match in Bromham yesterday afternoon.
Emergency services were called to Bromham Social Centre when the boy collapsed after complaining of feeling unwell while playing for Bradford Town Youth in a Mid Wilts Youth and Minor League under 14 cup match against Bromham.
There was a defibrillator on scene and first aid trained personnel and an off-duty paramedic provided CPR before the paramedics arrived.
An ambulance crew were on scene in five minutes, two paramedics in rapid response vehicles attended within ten minutes. Wiltshire Air Ambulance landed on the playing field at 3.05pm, carrying a critical-care paramedic and a critical care doctor from Great Western Air Ambulance attended in a car at 3.30pm.
On arrival, ambulance service clinicians immediately took over, including providing advanced life support, which re-started the boy's heart and breathing.
The attendance of a critical-care doctor meant the boy could be anaesthetised to allow him to be stabilised while he was taken to hospital.
The boy was taken to Bristol Children's Hospital by road as there were fears that weather conditions in Bristol would cause difficulties for the helicopter to land.
John Oliver, spokesman for South Western Ambulance Service, said: "Clearly the patient suffered an immediately life-threatening cardiac arrest and remains in a critical state.
"However, the excellent care he received throughout – even before we arrived at the scene – has ensured we were able to take him to the best location in a stable condition and he has therefore been given the very best chance of surviving and recovering."
Nick Maw, Chairman of Bradford Town Youth Football Club, said: "The club's thoughts and prayers are with the boy and his family at this time.
"We are waiting to hear news on the boy's progress but the emergency services were on the scene within minutes and did a fantastic job."


text:
Welcome to Experts at Laurier, a one-stop media resource featuring a broad database of experts who have agreed to make themselves available for media interviews. Contact them directly or call a media relations officer at 519-884-0710, ext. 3067 or 3070.
To search for a topic containing multiple words, please enclose the term in quotation marks, for example, "Canadian history"
Search Results
Your search returned the following Experts.
Click on the person's name for more information.
Professor Emeritus, Psychology
Areas of Expertise: Animal memory and cognition; Pharmacological analysis of behaviour; Effects of drugs on time perception and temporal memory; Animal research
Biography: The major objective of my research program has been to contribute to the area of comparative cognition by increasing our understanding of how animals encode and retain information. The research is focused on laboratory-based behavioural investigations…
Associate Professor, Psychology
Areas of Expertise: Behavioural neuroscience; Behavioural pharmacology of addictive drugs; Behavioural pharmacology of cannabis and related cannabinoid drugs; Effects of drugs
Biography: Dr. Mallet is a behavioural pharmacologist who studies the behavioural and neural effects of drugs, with an emphasis on drugs of abuse. …
519-884-0710 ext.2280


text:
Asia Society Associate Fellow Sheridan Prasso explains how off-the-books private lending is creating systemic risks in these two growing economies.
©2017 Asia Society | Privacy Statement | About AsiaSociety.org | Terms & Conditions | Sitemap | Contact
Asia Society takes no institutional position on policy issues and has no affiliation with any government. All views expressed in its publications and on its website are the sole responsibility of the author or authors.


text:
Rain washing a toxic roof coating into city storm drains caused substantial spill response by the Little Lake Fire Department and Willits public works personnel Thursday.
Crews were called out at 9:30 a.m. to contain the runoff from John's Place Kwik Stop roof at 255 East Commercial Street. The runoff was contained in the parking lot and nearby storm drains were covered. Only after the roof was totally power-washed and steam-cleaned that evening could crews return home.
The state Office of Emergency Services was notified of the spill by local responders. An inspector from the Mendocino County Environmental Health Department monitored the situation. Wardens from the California Department of Fish and Game are expected to conduct an investigation into the cause of the potentially toxic runoff.
The runoff was apparently the result of a failed attempt to coat the Kwik Stop roof with Henry Enviro White Roof Coating. The coating was not dry when the rains came, and apparently washed into the storm drain, according to sources at the scene.
The coating is not considered hazardous to humans, but is potentially toxic to fish.
The roof was thoroughly cleaned after the spill kept recurring as each new rain shower passed overhead.
The Material Safety Data Sheet for the coating advises to avoid runoff of spills to waterways and sewers. It contains the fungicide chlorothalonil as well as aluminum trihydrate and titanium dioxide.


text:
Castaway for A Day
Two people, one secluded beach and countless hours of time alone for snorkelling, surfing and fishing – does it get any better? When you're whisked away and "stranded" on this Private Cruise Experience, you won't exactly be roughing it: A gourmet barbecue basket is provided. You'll almost wish you didn't have to return to civilization.
Here's your chance to live out those deserted island fantasies.
Is this how you'll spend your extra time when you Stay Longer with Four Seasons Hotels and Resorts?
Advance reservations are required and offers are subject to availability. Offer details vary by property and certain terms, conditions, blackout dates and restrictions apply. Offers may not be combined with any other promotions/offers/savings. Only valid on new reservations. Terms and conditions are subject to change.


text:
Dr. Lisa Bootstaylor strives to create a plastic surgery experience and aesthetic result which taps into your inner most desires for timeless beauty. Excellence, dedication, perfection, and balanced beauty are essential themes which are integrated into her practice. Ultimately, the creation of a tailored, individualized, and beautiful result is her goal. With her extremely - well trained and professional staff they stand ready to assist you in making educated choices about your appearance, health and well-being.
Abdominoplasty Botox
Liposuction Sculptura
Rhinoplasty Body Contouring
Eyelid Surgery Breast Lift
Facial Rejuvenation Breast reduction
Breast Augmentation Facial Fillers
Scar-Sparing Breast Surgery Thermage
- MD - Albert Einstein College of Medicine, New York 1985 - 1989
- University of Pittsburgh: Dept of Plastic Surgery Residency, Pittsburgh, PA
- Mount Sinai Medical Center: Dept of Surgery Residency, New York, NY
- Wound Healing Laboratory: University of Califonia at San Francisco Fellowship
- American Board of Plastic Surgery 2001
- The American Board of Plastic Surgery 2001
- American Society of Plastic Surgeons
- American Medical Association
- Atlanta Medical Association
- Atlanta Women's Medical Alliance
- Crawford Long Hospital
- Dekalb Medical Center
- Dekalb Medical at Hillandale
- Northside Hospital
- Piedmont Hospital
- Rockdale Hospital


text:
SweetsLogic puzzles require you to think. You will have to be logical in your reasoning.
For being good at the garden fete, four children were each given two sweets. Jack had an orange sweet. The child who had a red one also had a blue one. No child had two sweets of the same colour. The child who had a green sweet also had a red one. Jim didn't have a red sweet and Joe had a green one. James didn't have an orange one and Jack had no blue sweets. Knowing that there were two sweets of each colour, can you tell the colours of the sweets each child had?
AnswerJack had an orange and a green sweet.
Jim had an orange and a blue one.
James had a red and a blue sweet.
Joe had a green and a red one.
What Next?
See another brain teaser just like this one...
Or, just get a random brain teaser
If you become a registered user you can vote on this brain teaser, keep track of
which ones you have seen, and even make your own.
Back to Top


text:
ORANGE – A chorus, an organ and the voices of parishioners filled Holy Family Cathedral on Thursday night as Orange County Catholics and other well-wishers gathered to pray in honor of the just-ended tenure of Pope Benedict XVI.
"Brothers and sisters, we are truly gathered here as one family of God to give thanks," said Bishop Kevin Vann of the Diocese of Orange, who led a special Mass to honor the pope, who Thursday officially became the first to resign in 600 years.
The 900-capacity cathedral was nearly full for the Mass, which also offered prayers for the successful election of a new pope. Parishioners and clergy recited an array of prayers, attendees took Communion and Vann gave a sermon about Benedict.
In between a typical sermon quoting relevant Bible passages, Vann took some time to tell of his personal relationship with Benedict. It's a relationship that Vann likened to that between a father and a son. The two met while Vann was a graduate student in Rome in the 1980s when the then-cardinal would stop and say hello, as he did with anyone he came across during daily walks.
Vann said he was not surprised when Benedict announced his retirement in February as he could see Benedict's health declining with his age. He thanked Benedict for his years of service to the church and for showing Catholics what it means to hope and believe.
Vann also looked forward to the future pope, saying, "Another will come and continue the journey of faith begun so many, many years ago."
Madonna Briscoe of Orange said after the Mass that she thinks it showed how committed the Orange County Catholic community is to the Catholic community around the world. Praying for Benedict and a new pope "just felt right," she said.
Mary Jo Gomez, 88, of Orange said she thinks Benedict is right in stepping down if he truly feels he cannot serve to his fullest.
"I do hope the new pope brings good tidings," she said.
Imelda Koone, 45, of Westminster said she was sad to see Benedict leave but is looking forward to a new pope.
"He knows what he's doing," she said. "I think it's very humble of him to step down if he doesn't feel he can continue."
Contact the writer: 714-704-3771 or firstname.lastname@example.com


text:
|Trad, 3 pitches, 310'
|YDS: 5.9+ French: 5c Ewbanks: 17 UIAA: VI ZA: 17 British: E1 5a R [details]
|Jim Erickson, John Behrens, Stand Badgett, 1969.
|Fixed Hardware:
|2 Lead Bolts, 1 Lead Pin, 2 Belay Bolts [details]
|Page Views:
|Submitted By:
|Patrick Vernon on Jan 1, 2001
|Comments on Hair City
|Add Comment
|Show which comments —
Comments displayed oldest to newest — Skip Ahead to the Most Recent Dated Sep 15, 2016
By Anonymous Coward
Jan 1, 2001
|I did this route today (3/9/01) and liked it very much. I led the 2nd and 3rd pitches. I thought the 1st was the most difficult and was glad I did not lead it (so I wouldn't have to clip any bolts not because of its difficulty).
By Charles Vernon
From: Tucson, AZ
Jan 1, 2001
|Note that this (phenomenal) route starts just right of West Buttress, below a large block which is located a little ways up the steep talus that rises up the west wall of the Bastille. Another locator which has been there for a while is an old cable slung through a tunnel near the base of the route.
By Chris Dawson
From: Denver, CO
Nov 26, 2001
rating: 5.9 5c 17 VI 17 HVS 5a R
|Near the top of the first pitch, just before it gets overhung for a few moves, there is a really solid #9 Stopper placement. This is directly below the left-slanting undercling crack in a little slot. This piece provides a little reassurance as opposed to placing iffy cams in the crack.
By Bryson Slothower
Apr 22, 2002
|The aformentioned "loose and runout climbing up to the crux" at the start of pitch 2 is only runout if you choose not to place gear. There is a good small cam placement before entering the steep section below the crux. Use long draws on this and the next piece and you can reach the top in one long pitch with no rope drag. I Don't bring anything larger than a .75 Camalot for this route, it's one of my favorite.
By Biggwave Dave
Oct 6, 2002
|I have done this route many times and feel it does not need to be rated serious. Reason being is that the first pitch can be well protected w/ some creative pro just left of the second bolt, the 1st pitch headwall also can take 3 to 4 placements, again w/ a good eye for the placements.
By George Bell
From: Boulder, CO
Oct 7, 2002
|I find the hardest move on this route is the mantle near the start. Once I was not concentrating (having led the route several times) and nearly lost my balance doing the move. As I recall there is a pin 5' below you here, but if it pulls or your belayer is asleep you could hit the ground. The middle of the first pitch is runout but it is very easy there. There are some large solution pockets in this section that will be full of water if you climb after a heavy rain (no problem, just unexpected).
By Rich Farnham
Apr 21, 2003
|Did this today and loved it!! Another Eldo classic! While I would agree with everyone above that the runouts aren't that big a deal (the climbing is solid, you can find occasional stoppers, etc.), I would disagree with the idea of not calling this an "S" rated climb. It IS a runout route. In general, the climbing is not harder than 5.7 in the runouts, but this ain't no sport route with a piece every 6-8 feet (and I'm glad it isn't). The fact that we all feel comfortable on it is great, but lets keep in mind that the purpose of this site is to provide beta. If you are just breaking in to 5.9, this route will most likely scare you. But, if you are used to Eldo climbing and haven't done it, go do this route! It earns its 3 stars.
By Anonymous Coward
May 7, 2003
|I seem to recall clipping a fixed pin near the bottom right side of the big belay flake (near the West Arete belay cleft), moving more or less straight left and slightly up from the pin, and then gaining a line of good holds near the left arete of the flake, which is followed to the belay spot. Just good old devious Eldorado face climbing, not crimps of death.
By steve dieckhoff
May 7, 2003
|To AC - regarding routefinding.... you make a good point. Looking up at the wall, find the large block/ledge a rope-length above you. The first pitch finishes by surmounting a bulge at the base of this block and angling left (runout except for a funky big stopper placement) and then up just left-of-center. To get to this block you'll find the 'bucket ladder' directly beneath. Getting to the first bucket is a bit runout but 5.6ish. It sounds like this is the point you reached. If you get to the bulge at the base of the block and don't like the looks of it you can easily escape to the right. Good luck.
By David Conlin
May 12, 2003
Regarding the rating:
One comment said it is 5.9, NOT 5.9+. I think the first pitch is maybe 5.9-, but lots of 5.8. It is the second pitch roof that is 5.9+.
Another disagreed with the S rating. If you are a solid 5.9 climber, experienced with tricky pro and confident in your placements, you may not "feel" runout on it. However, the S rating is to warn those that may be breaking into the grade or less experienced with pro of what they may be getting into. This is definitely warranted in this case. You MUST feel comfortable on 5.8 terrain, you MUST place pro opportunistically and in somewhat tricky ways, and you MUST NOT fall.
I think part of the fun is just finding your way up the wall. Who needs a detailed description on this route? It isn't tricky, just look for the easiest way and go.
By david goldstein
Jun 22, 2003
|The first pitch might be my favorite in the canyon.
By Edward Jenner
Sep 15, 2003
David, with all due respect, saying you MUST NOT FALL does not really help anybody assess a climb unless it has no pro. Otherwise what is the point of placing protection? Do you mean that you would not want to fall at any point on this climb? If so did you not trust any of your placements?
It sound like you are suggesting someone who attempt this should either be very confident that they will not fall except perhaps on the protected crux(s) or that they should be very good at placing pro.
By Anonymous Coward
Sep 15, 2003
I succeeded on the first pitch of this climb yesterday evening. I found it to be more challenging than other comparable 5.8/9 Eldo climbs. The middle section of the p1 meanders a bit and the path-of-least-resistance isn't obvious.
The headwall of the first pitch still has me scratching my head. There is an obvious crack/gash trending left from the stance up the headwall, but it quickly peters out to crimpers. In contrast, the climbing to the right of this gash is much easier. I took the path of least resistance and moved up the right part of the headwall (almost to the exit on the right), then traversed left across the face before heading up the slab to the top of the flake. This seems to be different than the guidebook's route description.
Where do most people generally climb to get through this section of Hair City? The way I went was so close to the exit, that it seemed contrived to traverse left and then move up the face to the top of the flake. -Matt Findley
By ac
Sep 15, 2003
Executive summary for Hair City: where a solid 5.8/9 climber needs gear, it is there and obvious. Where the difficulty eases, there are runouts ... none of which are too scary for again - a solid 5.8/9 leader. Probably not the best lead for someone who isn't a solid leader at the grade, but an absolute MUST DO for Eldo enthusiasts. If you need more info to feel comfortable about this one, follow it first to make sure you've got it in the bag. Being solid on 5.8 terrain and confident on 5.9 and even 10 will be a plus for the leader and not take away from the experience and exposure.
One of the best at the grade PERIOD and probably among the best 50 routes in Eldo regardless of the grade.
By George Bell
From: Boulder, CO
Sep 16, 2003
|Matt, I believe you followed the standard line. I recall maybe going somewhat right to get over the roof, then heading back left. Following the path of least resistance is the way to go there (follow the buckets!). It seems to me this is what Rossiter's topo indicates although he does not have his line going right over the roof (more like straight up).
By Charles Vernon
From: Tucson, AZ
Sep 16, 2003
Matt, I've led and followed it both ways, and it is perfectly doable to go straight up, but a bit harder and more poorly protected. Stepping right, up, then traversing is the more natural line, although as you say it seems odd to do so--when you step right, why not just continue up the easy chimney?
In fact, that's about the only thing I don't like about this route--it's a bit contrived (on both pitches), and therefore not as committing as comparably graded Eldo hair-fests such as Metamorphosis or Alice in Bucketland. But purely for the climbing moves, it can't be beat at the grade!
By David Conlin
Oct 9, 2003
Ed-In response to your comment in response to mine, you are right. I am suggesting that someone climbing this be confident on such terrain at such grade and experienced in placing pro. Otherwise it would not be safe.
I guess I slightly misspoke when I said you MUST NOT fall. I definitely wouldn't have wanted to fall. I trusted most pieces of gear I placed and with so much rope out, the fall factor would be low. If one was to fall during one of the runouts, the benefit of placing gear is that you probably wouldn't die (i.e. hit the ground). Rather you would take a large, scraping, swinging fall and may find yourself with significant injuries--something I strive to avoid. However, that sounds better than death.
By Mic Fairchild
From: Boulder
Nov 3, 2003
rating: 5.9 5c 17 VI 17 HVS 5a
One of my top 10 in Eldo, probably above W Buttress, because of its clean line. A wonderful lead, and a fabulous solo because the holds are so positive.
Did a nice line a couple weeks ago: up Hair City down Bastille Crack total time 19min 12sec from backpack-to-backpack.
Enjoy! Sic Mic
Don't slap rude and sail if you're shaky at the grade.
By Richard M. Wright
From: Lakewood, CO
Nov 8, 2003
|Tie in Mic. You're giving the kids the wrong impression.
By tim naylor
May 10, 2004
rating: 5.9+ 5c 17 VI 17 E1 5a R
|Best rock quality I've seen in Eldo. Lots of traversing and awkward moves. Eldo is funky. Good route for the area.
By Mike McKinnon
From: Golden, CO
Jun 16, 2004
rating: 5.9+ 5c 17 VI 17 E1 5a
|I did this route last week for the first time. I think overall it is a harder climb than the West Buttress. Definitely more sustained. I started the opening moves by using the small ramp for my hands and traversing under the layback. Once under I shot right up through it to the bolt. I have seen other people walk precariously along this ramp as well. I tried both and felt much better traversing underneath and firing straight up. I was also able to place a #9 stopper in the small flare at the bottom of the lieback before the pin. Makes the opening moves a little easier if not safer. The rest of the climb was great. The run out is not that bad as it is on solid buckets the whole way. There are definitely some places where you could get off route especially when approaching the end of the 1st pitch on the detached block. On the right is blank face so stay left for the easier ground right to the anchors.
By Michael Amato
Sep 14, 2004
|Climbed this route for the first time yesterday, what a treat! Runout for sure, but the pro is there at the difficulties. The first pitch is a gem, but don't miss the roof on the second pitch! Though it looks loose and chossy from below, some care on the lower foot holds gets you to super solid hand holds with great moves over the roof, and it's well protected with a bomber sideways #6 Stopper.
By Joe Sprague
Jun 26, 2005
|Marcel and I climbed it on Friday, June 24th. Great climb. Someone left a draw on the second bolt - maybe a result of the rain on the 23rd. If you want it back and can identify it, do so here with a phone number and I'll call you back. Otherwise, thanks.
By Eric Goltz
From: Boulder, CO
Oct 1, 2005
|I won't add to the gear-beta-blog-pile. Climb this route, it's fun!
By Edward Jenner
Aug 9, 2006
Finally climbed this, great route. Ac on Sep15 2003 comment nails the pro/danger issue.
I now understand what 'safe IF you are comfortable at the grade' means.
By Ernie Port
From: Boulder, Colorado
Sep 9, 2006
rating: 5.9+ 5c 17 VI 17 E1 5a R
|Although the mantle move down low may be the crux, the balancy move just above the second bolt, was a bit hairy too. Once you figure it out and move up, good small stopper placements are there. Up high on P1 I went to the right side, placed a #1 cam in a crack , traversed left to that little horn in the far left upper corner, and up to the top of the block, a series of moves made more exciting with that much rope out!
By Mike Robinson
From: Worcester, MA
Aug 22, 2007
rating: 5.9- 5c 17 VI 16 HVS 4c R
|Great route! Run out but you can get gear where you need it, any 9 leader should be fine on this route. The crux is on the first pitch and although it is run out the falls are clean. Get on it! I would agree with Mic, and by the way Mic, good job on the time!!!
By erik wellborn
From: manitou springs
Aug 27, 2008
|Best 5.9 in Eldo.
By Andy Laakmann
Site Landlord
From: Bend, OR
May 19, 2009
rating: 5.9+ 5c 17 VI 17 E1 5a R
|Fantastic climb on great rock. I only did P1, as my partner wanted to lead the far right upper pitch. On P1, the holds are mostly big and positive, and really the only tricky move is at the pin starting the pitch. I do think you want to be comfortable at the grade, but if you are.... get on this route. There is gear where you need it, and sussing out the path-of-least resistance is pretty straightforward (of course, everything was all chalked up for me). If it feels too hard, there is probably another way.....
By jcntrl
From: Smoulder, CO
Jul 9, 2009
rating: 5.9+ 5c 17 VI 17 E1 5a R
What a phenomenal route! I was glad to lead it today. I do think that the S/R rating is appropriate due to the runouts, but the hard moves on the first pitch are well protected. The 15'-20' runouts between bolts and gear force great focus!
As an interesting variation, I setup a belay to the right of the block after the aesthetic pockets section. Such a nice belay seat--reminded me of a motorcycle seat (slightly less padded, though)--with a great view to bring up your second. This is followed by a nice but short squeeze chimney to gain the top of the block.
The roof that is above this block is the money. Heading right, then up to gain a nice zigzag fingercrack was worthy of 9+ IMO. Now that I know the sequence it might feel easier next time, but onsighting was, for me, pumpy to commit and place gear; the ledge underneath looked unpleasant. The zigzagging fingercrack is 7ish, and fun the whole way.
By Rodger Raubach
Jun 14, 2010
rating: 5.9+ 5c 17 VI 17 E1 5a R
|My second-favorite route in Eldorado! Definitely commiting, though.
By Charles I.
From: Boulder, CO
Aug 15, 2010
First pitch was incredible.
The second pitch has some seriously sketch-ball blocks at the base of the roof. One block has been deservedly marked with the white X of death, and I second that motion.
By Ernie Port
From: Boulder, Colorado
Oct 15, 2010
rating: 5.9+ 5c 17 VI 17 E1 5a R
Led this route for the second time yesterday and remembered it well as one of those trad routes that really grabs your attention right from the start. The first pitch has so much climbing variety in it, mantling, thin crimpers, jugs, mini laybacks, traverses, and runnout in a nervey 130'. The finish of P1 can be done 3 ways...straight thru the jugs, over to the right then into the squeeze chimney (highly undesireable IMO), or to the right side of the finish block, then traverse left 15-20' to the corner and up (the money IMO)...very exciting finishing that way (runnout .7ish with BIG exposure there)!
So cool....
By John Behrens
Jan 3, 2011
|A little history ... we made the first ascent on a very cold December day -- hours before Royal Robbins showed his slide show of the first ascent of Tissaack on Half Dome. I led the first pitch wearing Royal Robbins shoes and, of course, no chalk, maybe with a stopper before that first mantle. After that it was just the 2 bolts. I then placed a small stopper near the lip of the roof. It gave me the heeby-jeebies, so I climbed down and the three of us tugged on it to test it. Jim then went up and led the over hang, and the rest was a walk.
By Evan Deis
Nov 11, 2012
|This line is scary.
By gumbotron
From: Denver, CO
Jan 27, 2013
|P1 is pretty spooky, keep it together out there...I'm no Eldo chossmaster and did not like the looks of P2, instead opted for the line out right which was really nice.
By Jay Eggleston
From: Denver
Aug 28, 2016
|Pitch two is fun and protects well with stoppers. We used two, and the second one was super bomber. Hard for the second to remove. Do it!
By WadeM
From: Golden, Co
Sep 15, 2016
|Currently a fixed stopper on P2 roof.


text:
Chef's Hat Recipe: Sweet Potato Pasta
Sweet Potato Pasta
1 12-ounce sweet potato, peeled and cut into 3/4-inch cubes
1 tablespoon olive oil
1 teaspoon chili powder
1/2 teaspoon cinnamon
1/2 teaspoon sugar
1/3 cup creamy peanut butter
8 ounces dried rigatoni (or bow tie pasta)
1 3-ounce package cream cheese, cut into chunks
2 teaspoons chili sauce
1 tablespoon soy sauce
6 green onions, sliced thinly
Preheat oven to 450 degrees. Oil a rimmed baking pan or cookie sheet and set aside. Place sweet potato cubes in a bowl. Toss with one tablespoon olive oil, the chili powder, cinnamon and sugar. Spread in prepared pan; bake for 20 minutes or until tender.
While potatoes are cooking, cook pasta according to package directions. Drain, but reserve one cup of the hot pasta water. Place the drained pasta in a medium sized bowl.
In a saucepan combine the peanut butter, cream cheese, chili sauce and soy sauce. Whisk in 3/4 cup of the hot pasta water. Stir over medium heat until heated through. If mixture is too thick, stir in additional water, a tablespoon at a time until mixture is of a creamy consistency. Stir in most of the onions.
Pour the sauce over the pasta. Add the cooked potatoes and lightly toss. Place on to plates and garnish with the remaining onions.


text:
White Lotus wrote:for example when i look at my hands there is no sense of 'mine' whatsoever; whereas in the past there was.
That's funny, when this first happened to me the very first thing I remember was looking at my hands (I was driving) and being like "what the f*** are these?" And then I remember being amazed that I had ever thought there was anyone here at all. It made me feel like I had been living a lie.


text:
For a Century, Van Cleef & Arpels Has Been Creating Distinctive Jewelry for the Rich and Famous
The onlookers could tell that something was afoot. How else to explain a regiment of Spanish-language television cameras arrayed along one wall of the auction gallery? All eyes were riveted to a striking blonde who arrived with an entourage just before the lot went on the block. She was all business--and she wanted that brooch.
But it soon became apparent that she had competition. Matching her, bid for bid, was an invisible telephone bidder. The scene resembled a tennis match: first the audience looked toward the blonde as she offered a bid, then its attention shifted to the telephone to wait for the counteroffer.
The presale estimate went by in a flash. After $500,000, it began to get interesting. Who would give in?
The bidding went past $600,000, then $700,000, then $800,000. Who was this anonymous bidder giving the blonde such a run for her money?
The crowd was on the blonde's side and groaned in unison every time the phone bidder upped the ante by another $20,000. When the invisible bidder offered $900,000, the blonde had had enough. Before her entourage knew what was happening, she was on her feet and, with an angry toss of her head, had stormed out of the gallery. The price for the brooch, including buyer's premium, was $992,500.
Who was willing to spend that kind of money for a piece of jewelry that represented Argentine history? Clearly, only two people had the desire to push the price of the brooch through the stratosphere.
There was the underbidder, Susana Gimenez, a top TV star in Argentina, who had flown from Buenos Aires specifically for the sale. And there was the successful bidder, who, according to the auction house, was a "private American male collector of historical objects."
Though Christie's has stood by this identification since the sale, last April, it never really made much sense. The person who played the role of purchaser of the brooch is the most fitting candidate: Madonna, onetime portrayer of Eva Perón in Evita, the film about her brief, theatrical life.
But perhaps the real winner was not Madonna but the maker of the brooch, Van Cleef & Arpels of New York. This little piece of jeweled history exemplified two of the famous firm's strengths: its mastery of the invisible-setting technique and its relationship with the most famous people of the day.
The light-blue sapphires that form the undulating blue bands of the Argentine flag are held firmly in place by the invisible-setting technique. This technical tour de force has been a hallmark of Van Cleef & Arpels since 1936. (Both Cartier and Van Cleef & Arpels received patents for the technique from the French patent office in 1935, but the technique had already been in use in small French workshops.)
The technique enables the jeweler to place gemstones side by side, row by row, without any visible means of support. There are no prongs, no wires, no metal beads holding the stones in place. The term "invisible setting" is perfect--it suggests a degree of mystery that is well deserved. The secret lies in the treatment of the stones themselves.
Underpinning the gemstones is a grid of metal, with tiny rods running in parallel rows. Channels are cut along the sides of each small gem, below the top facet. These precisely cut grooves allow the stones to slide into place on the rods. The surface of the jewel has the appearance of a garden of colorful stones, their facets capturing light and bouncing it back and forth.
Although invisible setting is nearly always done with rubies and sapphires, which are not enormously reflective stones, it is the multiplicity of all those tiny facets that gives the pieces their life. (Emeralds are rarely used, because they are more brittle; the number of stones that would be broken during the channeling process makes such pieces prohibitively expensive.) Rubies and sapphires lend themselves to the kind of designs for which the technique is best suited: the softly rounded curves of flower petals, feathers and leaves.
Successful invisible setting requires several tricks: the stones must be calibrated to the most precise tolerances in order to fit snugly together; they must be well matched in color and quality to give the most uniform appearance possible; and they must be channeled exactly so that when set, they create a smooth surface.
But fine jewelry--especially jewelry that emulates nature--is three-dimensional, not flat. The jeweler and the stonecutter, who work hand in glove to create this technique, must also allow for the curves of the design. The stones must be angled ever so slightly in relation to one another, so that they follow the arc of the petal or leaf. That means cutting one stone and placing it on the mounting, then cutting the next and placing it on the mounting, and so on.
Although the stones can be prepared in advance, when it comes to the setting, each one must be adjusted by trimming it a little here, a little there, turning little squares into tiny trapezoids. The tolerances are minute, the stones cut to within a hundredth of a millimeter. As with the most successful magic acts, the hard work should not show. And so it is with the very best invisibly set jewelry.
Great jewelry requires equally great clients. A firm such as Van Cleef & Arpels moves from the world of elegant commerce to the pages of history when its great works are worn by a regal clientele. Though Hollywood stars were "royals" in America during the period of jewelry design that began in the 1930s, the best-known royals were King Edward VIII of England and the American divorcée Wallis Simpson, who were destined to become the Duke and Duchess of Windsor.
Those titles were a paltry substitute for what Simpson expected (she really thought she would be the queen of England!), but His and Her Grace made do, and spent a lifetime of luxurious exile in the public eye. After the war, these elegant refugees, deprived of the usual round of official duties, utterly devoted themselves to their appearance. The duchess was never seen without exactly the right jewel, or jewels.
"The Duke was known to have spent long hours in the pre-war years with Jeanne Toussaint of Cartier, and with Renée Puissant at Van Cleef & Arpels, both eminent designers in their field," Sotheby's senior director Nicholas Rayner wrote in his forward to the catalogue for the sale of the duchess' jewels, held at Sotheby's in Geneva in 1987. "The relationship between these two highly imaginative artists and their Royal client often produced jewels which were still considered avant-garde ten years after their completion."
Although a couple of the major gems in the Sotheby's sale brought more money, the outstanding piece of jewelry at the auction was the invisibly set ruby-and-diamond clip made by Van Cleef & Arpels of Paris in 1936.
The brooch, with its scallop-edged frame emulating the shape of holly leaves, comprises one leaf studded with gracefully tapering rows of invisibly set rubies, and the other pavé set with round diamonds. The vein of each leaf consists of a single row of tapering baguette diamonds. The original design for the brooch, rendered in full color, accompanied the photo of the piece in the catalogue. It reveals the remarkable faithfulness with which the craftsmen created the brooch. The six-inch-long jewel may have been the first piece Van Cleef & Arpels made using the invisible-setting technique. When it was sold at the 1987 auction, the brooch brought nearly $1.1 million, more than nine times the original estimate.
For a century, Van Cleef & Arpels has been steeped in a tradition of gemology and jewelry making. Charles Van Cleef was a Dutch gem cutter in the mid-nineteenth century who, restricted by limited business possibilities in Amsterdam, saw in the extravagant balls and receptions of Paris a boundless opportunity to sell his wares. He moved there in 1867, arriving just before the fall of Napoleon III's empire. In spite of the bad timing, Van Cleef's business prospered. He soon married, and his son, Alfred, was born in 1873. It was Alfred who, with the Arpels family, ultimately set up the firm that we now know as Van Cleef & Arpels.
In 1898, Alfred amalgamated his personal and professional life by marrying his cousin, Estelle Arpels, and forming a small jewelry business with two of Estelle's brothers, Charles and Julien. They quickly outgrew their small offices and, on June 16, 1906, opened a new shop at 22 Place Vendôme, the most elegant street in Paris, where the firm remains to this day, albeit in larger premises. The three principals were an ideal combination, each bringing a different talent to the mix. In 1912, they were joined by the youngest Arpels brother, Louis.
Van Cleef & Arpels may not have had the society-based French business that Charles Van Cleef had hoped for, but it did well with the royalty of other nations. Before the First World War, Paris was filled with titled Europeans, as well as Indian princes and untitled but wealthy Americans, who kept the jewelers busy. The firm was quick to set up satellite offices wherever customers were to be found, catering to the social set in their own stomping grounds, such as Deauville, Nice, Biarritz and Vichy. In a move that anticipated current marketing techniques, these branches were open only during the high season.
In some of its themes, Van Cleef & Arpels followed the styles of the times. The great fashion-making event of the early 1920s was the discovery in Egypt of the tomb of King Tutankhamun, in 1922. An explosion of Egyptian-motif designs followed.
The design world was captivated by the themes of hieroglyphics and the distinctive flat Egyptian profiles that defined the period. Exceptional bracelets were made in this style--they are small murals, strips of history both in design and in execution; the buff-top, or smoothly polished, colored stones used to fill out the bird and flower designs had the carefree abandon of a child at play with finger paints.
Red, blue, green and black set against white diamonds lent these pieces a particular liveliness; the small stones used provided the needed restraint. Fine platinum mounts, hallmarks of the period, enabled the jeweler to create precise portraits and scenes. Each small stone was cut to fit the mount; but, unlike the invisibly set jewels that would come later, the lines of these settings helped to define the pictures being painted through the use of gemstones. Among the Art Deco jewels, these bracelets are among the most coveted, not only for their beauty and technical brilliance but because they are eminently wearable.
The foundation for the firm's next phase was set when Alfred's and Estelle's daughter, Renée, married Emile Puissant, a young lieutenant she had cared for as a nurse during the First World War. Emile enjoyed a brief but highly successful career as a salesman and administrator in the Arpels firm until he was killed, at the age of 38, while driving his Bugatti. His widow took her own place at the firm as artistic director, proving to be the guiding light of design from 1926 until her untimely death, in her middle 40s, in 1942.
Throughout those crucial years, a flow of invisibly set pieces came into being. Although Renée could not draw, she was ultimately responsible for the look of the jewelry. Working together, she and designer René-Sim Lacaze were instrumental in creating the look of the firm's pieces between the two world wars.
During this period, King Edward VIII, who was the Prince of Wales before he ascended the throne in 1936, purchased several dramatic designs, including two diamond bracelets: one set with rubies, the other with sapphires. These pieces are historic documents. Each carries, as do all Van Cleef & Arpels jewelry, the firm's name, the city in which the piece was made, and an identifying number. In addition to the usual hallmarks, each was inscribed with a personal message.
The ruby-and-diamond bracelet, purchased in 1936, features 40 substantial rubies set within a frame of diamonds. The inscription reads: "Hold Tight 27-iii-36" (March 27, 1936). At the time, Wallis Simpson was still married to Ernest Simpson, and the Simpsons, as well as King Edward, were spending the weekend at Fort Belvedere, the king's guest house outside London. In this soap-opera environment, the king gave Mrs. Simpson the bracelet. The inscription conveyed the message that Wallis should hang on until their "little problem" was straightened out.
The king apparently had good reason to believe that a resolution was near: at a meeting between himself and Ernest Simpson, thought to have taken place several weeks earlier, Simpson had agreed to end his marriage to Wallis if Edward "promised to remain faithful to her and look after her," according to an anthology of letters between the king and Mrs. Simpson that was later published.
By 1937, the little problem of wanting to marry a twice-divorced woman had been resolved, and in honor of their upcoming union, Edward presented Simpson with the sapphire-and-diamond bracelet.
Edward, who had never been crowned in a formal coronation, had abdicated in late 1936 in favor of his younger brother, George, and the couple were free to marry. To seal the deal, Edward, who would henceforth be known as the Duke of Windsor, gave Simpson what has become known as the marriage contract bracelet. It is a remarkable example of invisible setting. The sapphires in the central panel are cushion-shaped. The bracelet is inscribed "For our Contract 18-V-37" and was intimately connected with the actual marriage contract.
Log in if you're already registered.
Or register for Cigar Aficionado today—it's free.
Registration allows you to:
Keep track of your favorite cigars in your personal humidor.
Comment on all our stories.
Ratings & Reviews
Search our database of more than 17,000 cigar tasting notes by score, brand, country, size, price range, year, wrapper and more, plus add your favorites to your Personal Humidor.


text:
Regional Theater of the Week: Delaware Theatre Company in Wilmington, DE
BroadwayWorld.com, the largest theatre site on the Internet, is excited to announce a new feature to its comprehensive regional coverage - the Featured Regional Theater of the Week! Each week, BWW will introduce its readers to a regional theater located in one of our (over 130!) coverage cities. By exploring these different venues, their history and showcasing the production seasons, BWW continues its commitment to expand our presence in communities and cities across the United States.
This Week's Featured Regional Theater: Delaware Theatre Company (DTC) in Wilmington, DE
Founded in 1979, Delaware Theatre Company (DTC) is Delaware's premiere non-profit theatre. Now in its 34th season of award-winning theatre, DTC is located in the heart of Wilmington's thriving Riverfront. Led by Executive Director Bud Martin, DTC produces a diverse season of plays, including musicals, new works, and the classics, attracting professional actors and artists from Broadway and regional theatres across the country. DTC has produced more than 150 plays for over one million residents and visitors to its community. The education and community outreach programs are nationally recognized and serve thousands throughout the tri-state area.
DTC produces five professional theatrical productions each season along with an array of meaningful education and outreach programs. DTC's mainstage programming has explored the entire canon of American and world theatre, from 20th century classics like The Piano Lesson by August Wilson, Private Lives by Noël Coward and Our Town by Thornton Wilder to contemporary plays like Mitch Albom's Tuesdays with Morrie, Proof by David Auburn and Picasso at the Lapin Agile by Steve Martin.
DTC has produced original productions from the works of William Shakespeare, Sophocles, and Moliére as well as world premieres by emerging playwrights including Kevin Ramsey, Aaron Posner, and Tazwell Thompson.
DTC's artistic programming has been awarded 12 Barrymore Awards for Excellence in Theatre by the Theatre Alliance of Greater Philadelphia. DTC's nationally recognized education programs reach out to all sectors of the community. The popular Theatre in the Schools student matinee program provides meaningful arts access and enrichment opportunities to middle and high school students from a four-state radius and includes a performance of a DTC production, classroom visits by DTC teaching artists, post-performance conversations with members of the cast and an original standards-based study guide called Insights, which gives teachers pertinent background information on the play, the playwright, and the DTC production, as well as teachable moments from within the script.
For than past twenty years, DTC has been a leader in access to the arts for youth at risk. The cornerstone of these offerings is the Totally Awesome Kids, a program for individuals with developmental disabilities ranging from mild retardation to Down's syndrome and autism. This program, which uses theatre games, group activities and exercises to help participants with verbal, listening, and socialization skills has been the recipient on national recognition for excellence in community service. A similar program, the Pro-Actors was launched in 2007, and provides unprecedented socialization opportunities for children with disabilities on the autism spectrum.
DTC is also well known for its 13-year partnership with the Ferris School, a level five maximum-security prison for incarcerated teen boys. DTC education staff and actors participate in residencies at Ferris School, which includes work in drama, movement, visual arts, music and spoken word/poetry.
The 2012/2013 season includes THE OUTGOING TIDE by Bruce Graham directed by Bud Martin, A CHRISTMAS CAROL by Charles Dickens, in a new adaptation by Patrick Barlow, directed by Joe Calarco, BOEING BOEING by Marc Camoletti translated from the French by Beverley Cross & Francis Evans, LOVE, LOSS AND WHAT I WORE by Nora Ephron and Delia Ephron, and SOUTH PACIFIC music by Richard Rodgers, lyrics by Oscar Hammerstein II, book by Oscar Hammerstein & Joshua Logan, directed by Bud Martin.
For tickets or more information about DTC, please visit: http://www.delawaretheatre.org/
Know of a theater we should feature? Send your suggestion to email@example.com.
Information and photos courtesy of Delaware Theatre Company (DTC).


text:
I play this for fun, but as with golf, I have more fun when I play well. I have no idea what I should expect as far as progress. I started keeping scores within a couple weeks of buying my first discs.
August 22, 2012 - 87
Stayed in the 80s until September 30, and shot 72. Obviously, form was changing, and distance increasing.
In the 70's until October 17 with a 68.
Today(1-31-12), shot my personal best of 62. Felt easy. No lucky breaks. Only one birdie(depending who you ask).
Is that about right? I'm on the verge of reaching a couple more holes that will potentially give me birdies, but 60 is looking like a massive brick wall right now.


text:
CRAGSMOOR, N.Y. -- A woman killed her husband with two gunshots to the head and then died after taking pills, the Ulster County Sheriff's Office said on Thursday.
Undersheriff Frank Faluotico said the case was being treated as a murder-suicide.
The Sheriff's Office said deputies went to 40 Dellenbaugh Road in the Wawarsing hamlet of Cragsmoor at 7:32 p.m. Wednesday after being told neither Paul W. McCombs, 62, nor Sharon K. McCombs, 61, had been heard from in more than 24 hours.
Faluotico said a family member who was not in the area asked authorities to check on the McCombs. He said the couple lived alone and were found dead in a rear bedroom of the single-story, ranch-style home.
The preliminary investigation, according to a Sheriff's Office report, found Mrs. McCombs shot her husband twice in the head with a small-caliber handgun and then died after ingesting an undetermined amount of prescription medication.
"Our investigation at this point revealed she (Mrs. McCombs) only fired two shots, both striking the male subject," Faluotico said on Thursday.
The undersheriff said the crime scene was not in disarray and that there was no sign of a struggle. He also said the Sheriff's Office is looking into the gun's origin and whether it was possessed legally.
The Sheriff's Office said there appeared to be no other victims or people involved in the case, though leads were being pursued.
Faluotico said autopsies on the McCombs would be performed on Friday. Toxicology tests also will be conducted.
Faluotico said the Sheriff's Office had handled "domestic related" incidents involving the McCombs in the past, but he would not elaborate.
"We have handled other incidents at that residence," he said.�
The Freeman's archives show Mrs. McCombs was charged by state police at Wawarsing in June with felony criminal mischief and driving while ability impaired by alcohol, a violation.�
Anyone with information about the McCombs or their actions during the days leading up to the murder-suicide is asked to contact Detective Sgt. Abram Markiewicz at (845) 340-3956 or email@example.com.


text:
The Cleveland Indians came out of left field by agreeing to a four-year, $48 million contract with center fielder Michael Bourn on Monday night.
Now they just have to figure out how to fit him into their lineup.
Bourn gives the Indians three players—Drew Stubbs and Michael Brantley are the others—capable of playing center field. That job likely will go to Bourn, meaning Stubbs either could be traded or new right fielder Nick Swisher could move to first base (with Brantley and Stubbs playing corner-outfield positions). In that scenario, new first baseman Mark Reynolds could take over the DH duties. Of course, Cleveland recently agreed to a minor league contract with Jason Giambi, who projected as the primary DH if he made the 25-man roster.
According to The Plain Dealer, Indians general manager Chris Antonetti and manager Terry Francona have yet to comment on all of the possible lineup possibilities because they have yet to speak with each of the players who will be affected.
The newspaper notes Bourn likely will take his physical Wednesday, followed by a press conference Thursday and the team's first full-squad workout Friday.
Fantasy: Impact of Bourn signing


text:
Where to Begin?
Browse this handout (click to download)
Need Help?
There are many ways to ask us questions. We're here to help you!
Your Muskingum ID is Your Key to Library Services!
Your Muskingum ID allows you to borrow items from the library, request items from other OhioLINK libraries, use OhioLINK's Pick-Up Anywhere service, and use our research databases off-campus. You will receive a Muskingum ID at the start of class.
If you lose your ID, you will need to contact Aramark's Campus Services Office for a replacement. Campus Services is located at 24 Stadium Drive which is to the west of the Rec Center. Their phone number is (740) 826-8147 and their email address is firstname.lastname@example.com
Your Record
How to activate Your Account
If you registered for classes on-time, your record will have been created automatically.
If you register for classes late you will need to have a library record created manually. To create your record you may:
How to check Your Record online
You can use your online record for the following: check due dates; check fines; renew books; cancel a book request
What are OPAL and OhioLINK?
OPAL is a consortium of 24 private academic libraries located throughout the state of Ohio. OPAL was created in 1999. Member institutions share a common public catalog and allow members to borrow circulating items without charge.
OhioLINK a consortium of 89 Ohio colleges and universities and the State Library of Ohio. In addition, books from Cuyahoga County Public Library and Westerville Public Library are included in the OhioLINK catalog and available for requesting. OhioLINK is the primary provider of our research databases, electronic books, and electronic journals.
Muskingum Catalog
The Muskingum Catalog is accessible from every page on the library's web site in the link menu at the top of the page, or from the Find a Book page. Search the catalog to locate items owned by Muskingum.
OhioLINK Catalog
The OhioLINK Catalog is accessible from every page on the library's web site in the link menu at the top of the page, or from the Find a Book page (also a link at the end of this section).
Search the OhioLINK catalog to locate items owned by most institutions of higher learning in Ohio. Click on "REQUEST THIS ITEM" and then select "Muskingum University" when asked to select your school or institution. You will be asked for your name and barcode number. Books requested from OhioLINK will take 2-3 days to arrive at Muskingum. An email will be sent to your @muskingum.edu account when the item is available for pick-up.
What is Pick-Up Anywhere?
When you request a book through the OPAL or OhioLINK catalog, you have the option to have it delivered to any OhioLINK member library in the state. So, if you lived in Newark, you could choose to have books delivered to the library at Denison University or OSU-Newark/COTC and pick up the books there using your Muskingum University ID. Simply choose another Pickup Institution and Pickup Location instead of Muskingum University.
Research Databases
The Library provides access to over 150 research databases. Use these databases to find journal articles. Many of our databases provide abstracts and some include the full-text of the article. If the full-text is not available click on OLinks/Find It to see if the full-text is available in the Electronic Journal Center or another database.
How to Use Research Databases
How to use Research Databases from Home or Work
Find the database you want to use on the Databases page or a Subject Guides. You will be redirected to an authentication server where you will be asked to:
Can't Get Into a Database from Home or Work?
If you are having problems accessing a research database off-campus:
Interlibrary Loan
If you find a citation for a book that is not available from OhioLINK or for a journal article that is not available in print or electronically then you may request it using Interlibrary Loan.


text:
CHINO – Business owners are welcome to attend the I.E. West-End Business Growth Conference on Thursday.
The event begins at 7:30 a.m. with registration at Chaffey College's Chino Community Center, 5890 College Park Ave., Chino.
The conference will include a panel discussion from 8-9:30 a.m., and from 9:30-10 a.m. those attending will get a chance to network with other business people.
Attendees should be experienced business owners with projected growth potential in 2013, businesses seeking tax credits or grant funding adding new employees, businesses interested in exploring new revenue options through government contracting, businesses interested in the commercial real estate outlook in the Inland Empire, businesses ready for growth capital for expansion and CPAs, real estate professionals, and other service providers who support growing businesses.
The workshop is free and brings together resources for businesses, including job training, contracting opportunities for doing business with the government and a report on the outlook of commercial real estate in the Inland Empire West-end market.
Discussion topics:
-The U.S. Small Business Administration and lending programs
-loans, lines of credit, export programs and lending programs for women, minority, and disabled veteran owned businesses
-government contracting: getting started and taking advantage of contracts
-tax credits and rebates for hiring new employees; training programs for the workforce
-commercial real estate outlook for the Inland Empire.
To register contact: Chino Valley Chamber of Commerce, 909-627-6177.
Registration is required due to limited space.