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"We wanted to make a sort of 'lowbrid' – a cross between a videogame and an album," says Super Furry Animals frontman Gruff Rhys. For years, the Welsh pop quintet has mixed the audio with the visual; on 2001's dystopian Rings Around the World, the band even had 18 directors (one per song) make short films for a DVD to accompany the CD.
This article has been reproduced in a new format and may be missing content or contain faulty links. Contact firstname.lastname@example.com to report an issue.
On the new release, Phantom Power, the band didn't want the video to overwhelm the music. The Animals pursued fellow Cardiff native Pete Fowler, the man behind their past three album covers and the Monsterism line of collectible figures. Fowler created animated shorts for each of the 14 songs the band had recorded. Inspired by his work, the Animals then cut separate instrumental tracks for the shorts. Fowler returned to the original songs and crafted visual wallpaper that morphs and undulates while the tunes play. The end result: Fans can enjoy the album with the wallpaper, or the shorts with the ambient soundtracks.
In the tradition of British psychedelic rock groups since the '60s, the Animals have their roots in art school – Rhys studied fine arts, keyboardist Cian Ciaran film, and drummer Dafydd Iauen painting – but their aesthetic isn't exactly Pink Floyd. "I hate The Wall," says Rhys, who cites the Butthole Surfers as more of an inspiration. "I absolutely hate that shit."Go Back to Top. Skip To: Start of Article.


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Multiples of 7Logic puzzles require you to think. You will have to be logical in your reasoning.
There are eight different 2-digit numbers: AD, BA, BG, CE, DB, DH, EF, and FC. Each is less than 70 and divisible by 7. Each of the distinct letters represents a different digit. The same letter represents the same digit. Given E=5, what is G?
Since E=5, F=6 and C=3.
The remaining numbers divisible by 7 are 14, 21, 28, 42 and 49. The number 1 appears in the tens digit only once; therefore, A=1, B=2, D=4, G=8, and H=9.
What Next?
See another brain teaser just like this one...
Or, just get a random brain teaser
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subset: commoncrawl


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Annie_Pannies's Blog
Sat, Aug 20, 2011 at 7:44 AM
A Little Something. . .
What it do fellow Nicki fans?! Just trying to get my page going here tired of it looking all boring! I knw i could relate to most of you guys! Being that were all die hard fans! I've been a Nicki fan since 2007! Im a ride or die kinda chick lol i stick with her thru thick & thin! I got my moment for life on April 19th 2011 in Phoenix,AZ. I was so excited and soo happy that i finally got to meet...


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I apologize in advance if my question is out of place for such a forum, but I was hoping to receive the opinions of those who practice Vipassana.
A little background: I took a couple of 8 week courses in Mindful Meditation, which had been to assist in the treatment of my diagnosis of depression. I did learn the basics of Vipassana and had learned to observe the mind. I found it to be somewhat helpful while I was meditating and I enjoyed the learning process. Unfortunately, I didn't continue much after the courses ended.
Present time: I was diagnosed with Complex PTSD two years ago (the depression wasn't an accurate diagnosis 20 years earlier). I've been considering an S.N. Goenka 10-day retreat to enable myself to essentially "stop judging" the thoughts/memories that keep racing through my mind. The memories are invoking such sad emotions, but they're memories that I'm chosing to think about (as opposed to "flashbacks").
One small concern of mine is that meditation may bring up memories that I haven't remembered (if there are any left.) I believe I'm fully facing my memories, but I'd like to be able to remove the emotional reaction to them. My biggest concern about being at a retreat is, should I not be able to simply observe my thoughts and begin to cry, I will be dissruptive to the other students.
Any thoughts, experiences or suggestions would be appreciated.


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CINCINNATI Macy's Inc. said it plans to hire approximately 65,000 seasonal associates in its stores, call centers, distribution centers and online fulfillment centers nationwide for the 2010 holiday season. The hiring plan represents a slight increase from previous years, reflecting the company's expectations for same-store sales in the second half of fiscal 2010 to be up by 3% to 3.5%, Macy's reported.
"It is vitally important that our customers are well-served during the busiest shopping time of the year. So we ramp up our workforce starting now and running through December," said Terry Lundgren, Macy's Inc. chairman, president and chief administrative officer. "Our seasonal associates serve customers on the selling floor, work behind the scenes in store operations positions, interact with customers via the telephone in call centers, and staff the distribution and fulfillment centers that coordinate shipments to our stores and directly to customers who buy online."
Applications for seasonal positions at Macy's are being accepted online now at www.macysJOBS.com. Candidates who fill the company's criteria will receive by email an invitation to interview. Hiring for store sales positions will begin in early October. Hiring for operations positions already has begun.
"Working in a seasonal position at Macy's is a great way to earn extra money at the holidays. Many of our seasonal hires are students on break, stay-at-home parents, individuals in career transitions or those with extra time they would like to use productively," Lundgren said. "Retailing is a fast-paced business, and working at Macy's during this magical time of the year can be fun and rewarding."


text: Grand Hustle [ OMG Girlz Give Behind-the-Scenes Look at New Photo Shoot — Exclusive By Georgette Cline March 9, 2012 Beauty, 15; Star, 15; and Baby Doll, 16, are a colorful bunch. The trio, who comprise the singing and rapping set known as the OMG Girlz, don pink, green and purple hair, rock glittering ensembles and accessorize with dazzling rings and things... Read More Category: Exclusive, Hip-Hop, R&B Tags: gucci this gucci that, GucciThisGucciThat, OMG Girlz, OmgGirlz, T.I., Tameka Cottle, Tameka Tiny Cottle, TamekaCottle, TamekaTinyCottle, the omg girlz, the omg girlz gucci this gucci that, TheOmgGirlz, TheOmgGirlzGucciThisGucciThat, Tiny EMAIL SHARE TWEET Pin it! REDDIT Share on Tumblr!


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DN 31: Sigalovada Sutta
The householder's code of discipline, as described by the Buddha to the layman Sigala. This sutta offers valuable practical advice for householders on how to conduct themselves skillfully in their relationships with parents, spouses, children, pupils, teachers, employers, employees, friends, and spiritual mentors so as to bring happiness to all concerned.
DN 31 PTS: D iii 180
Sigalovada Sutta: The Discourse to Sigala
The Layperson's Code of Discipline
translated from the Pali by Narada Thera
http://www.accesstoinsight.org/tipitaka ... .nara.html
DN 31 PTS: D iii 180
Sigalovada Sutta: The Buddha's Advice to Sigalaka
translated from the Pali by John Kelly, Sue Sawyer, and Victoria Yareham
http://www.accesstoinsight.org/tipitaka ... .ksw0.html
The Digha Nikaya suttas are rather long, and it seems a little pointless to cut and paste the text here, since the formatting is much better if you read them on the Access to Insight site.
This particular Sutta collects together a huge amount of advice on how lay people should conduct themselves and finally re-defines worshipping the six directions in terms of the development of relationships.
I reall Bhikkhu Bodhi saying in some talk or other that it was suttas such as this one with practical advice about how one should conduct one's life, look after one's parents, and so on that really convinced him of the Buddha's wisdom, not the deep suttas on dependent origination and so on...
Unfortunately, I can't locate that particular talk right now. Perhaps someone else recalls it?


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Dear friends,
I am now trying to find out which businesses are suitable for a practitioner.
Definitions of "Right Livelihood" that I am acquainted to do not exclude entertainment industry (e.g. organizing music shows), but 8 precepts and further sets of precepts propose practitioner to abstain from attending entertainments. Sigalovada sutta also recommends layman not to be a frequent theater-goer. Finally, there is a sutta where Buddha says that actors are going to hell (anyway, it seems unrealistic to me that Buddha could say that ALL actors will be reborn in hell).
Having an experience in public relations, I know that it often deals with half-truth. Especially when everything that is stated by a PR person is true but the real situation is different from one formed in minds of receivers of such information
And at least some types (I guess, most types) of modern advertising are aimed to developing kama[-chandha] to the advertised objects.
Buddha recommended to Rahula to reflect on his actions in such way: "Whether this action creates happiness or suffering for me and other beings?" So, the question I ask is "If this business develops skillful or unskillful qualities in me and its' contact groups / stakeholders?"
So please help me to find a limit of suitable work for a practitioner.
I'm especially interested in answers from those well-versed in Tipitaka and those who have already researched this topic and made such decisions.


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The Hub Magazine has awarded Kmart's pun-drenched campaign, "Ship My Pants," best of show honors in its third annual Hub Prize competition. Draftfcb Chicago was the agency for the campaign.
"Ship My Pants prevailed because it solved a problem for shoppers — out-of-stocks — with a truly meaningful promise: If you can't find what you're looking for in our stores, you can order the item online, on-the-spot, and have it shipped, free-of-charge, to your home," said Hub Magazine founder Tim Manners.
At the center of the campaign was a YouTube video in which various Kmart shoppers riff on the phrase "ship my pants" to off-color, comic effect ("Ship my pants? Right here?"). With an initial budget of $85,000, the result was a sales increase for Kmart, as well as a viral buzz. To date, the video has received more than 19 million views on YouTube alone.
Kmart interim chief marketing officer Andrew Stein said that "Ship My Pants" was effective both because it was funny and because it communicated an important message — namely that if the store doesn't have an item in stock, consumers can order the item and have it shipped to their homes free.
As the Hub Prize best of show winner, Kmart is the recipient of the Hub Cup, a hand-crafted, solid-bronze trophy. A total of 36 Gold, Silver and Bronze medals were awarded based on evaluations by a panel of 25 judges, including leading academics, bestselling book authors, industry analysts and high-profile veterans of major brands and retailers. All winners are featured in the Nov./Dec. edition of The Hub Magazine.
Founded in 2004, The Hub Magazine is written for senior-level marketers at the world's largest companies and is dedicated to exploring innovation as the ultimate driver of the brand experience. The Hub also hosts The Hub Live, an annual symposium centered on the brand experience, and sponsors The Hub Top 20, an annual ranking of excellence in shopper-marketing capabilities.


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Nicasio, Escalona all smiles day after scuffle
DENVER -- Rockies pitchers Juan Nicasio and Edgmer Escalona treated fans to a scuffle during Thursday's public workout at Coors Field, but they were smiling and hugging again Friday before the home opener.
"It's no big deal because Escalona is my best friend," Nicasio said. "It was a bad day. Something happened."
Escalona said, "It's like a brother, family. That's what happens all the time."
In fact, the two rode to Coors Field together for Friday's game.
"We do everything together," Escalona said. "It happened because we're together too much. Sometimes we've got to fight."
Thomas Harding is a reporter for MLB.com. Read his blog, Hardball in the Rockies, and follow him on Twitter @harding_at_mlb. This story was not subject to the approval of Major League Baseball or its clubs.


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If you receive our newsletter, this information may be redundant, but we got very positive feedback about our newsletter for January 2011 and I thought I would go ahead and share the same information here. If you are not familiar with our e-newsletter and would like to receive articles and announcements of which product are on special each month, please visit here and sign up.
With the start of a new year, we often find ourselves reevaluating our lives and trying to make improvements. For most of us, that usually involves some commitment to eating better/healthier/cleaner. To help you navigate all of your options, I've put together some definitions for the common terms you'll encounter on food labels. To get us started, let's start with the most common and often most confusing terms- Natural and Organic. In subsequent posts, I will define Whole Grain, Gluten Free and Kosher.
Natural: Probably the most common and most misunderstood term on labels today. What does it really mean? Absolutely nothing; there are no regulations regarding the use of the term "natural" and can be applied to any product. At Bob's Red Mill, we use the term natural to describe our use of quality ingredients in their most natural state with minimal processing. Be careful when the product seems too good to be true, it very easily could be. If you are skeptical that the brand of dish soap you are using is really "natural," it is worth the extra time to investigate. Most companies who are using the term "natural" truthfully will have a good explanation about their processes and ingredients on their website.
Organic: Unlike the term "natural", "organic" is highly regulated and strictly enforced by a governing agency. The National Organic Program follows the Organic Foods Production Act of 1990 to ensure "site-specific conditions by integrating cultural, biological, and mechanical practices that foster cycling of resources, promote ecological balance, and conserve biodiversity." If you see the term "Organic" you can be sure that the products have been inspected to meet the requirements of the act. This term has no relation to whether the product is nutritionally sound or not.


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"I FEEL devastated."
Those were the words of a pub landlord who has been forced to leave his Winchester home and business, just eight months after uprooting his family to work there.
Mark Vincent, 42, along with his wife Jo, 44, and son Sam, 11, lived and worked at The Ship Inn, in Wales Street, but have been booted out after Marston's sold it to Hampshire-based nursery firm Yellow Dot.
The couple closed the doors for the last time last Friday night after a leaving party, and said that their regulars were in tears about the closure.
Mr Vincent said: "I'm gutted really. I feel devastated for everybody – they found a safe pub where they could drink and now it's gone. Loads of them were crying, a lot of people have grown up with the pub and it has been around for 40 years."
Mrs Vincent said that work men had virtually destroyed the interior before they had left on Monday.
"It was absolutely awful," she said.
"Three work men claw hammered every picture and every mirror and took the bar apart. It was soul destroying. Everything attached they took out. They were ruthless, the place looks derelict now."
She added: "The worst part is that they have the keys until May 16, so I said 'why couldn't they have waited until we had left?' There is no reason to put us through that."
Winchester City Council registered a planning application on April 29 for a change of use for the building, which could see it transformed into a nursery catering for up to 70 children.
The family have moved back to the Isle of Wight, where they had left behind four children and five grandchildren.


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The Reel Life: Reality TV producers turn cameras on selves
SPRINGFIELD, Ore. - The folks who brought you the reality show "Graveyard Carz" have a new project in the works: a reality TV show about making reality TV shows.
The crew at The Division Productions in Springfield is finishing up the sizzle tape for their newest pitch: "The Reel Life," a reality show about making reality TV.
"It's a little bit weird," said producer Casey Faris."Like the other guys, I'm used to being behind the camera. This is just a little bit uncomfortable for me."
"I think making reality television about reality television is an interesting conundrum," said editor Dan Bernard, "because no one's done it yet."
Mark Worman, the owner of The Division Productions, said he hopes "The Reel Life" will find the same success as his other series.
"At the end of it, you're going to walk away with some technical stuff, you're going to learn a little bit about what we have to do and the equipment that we use, and more importantly the mindset behind the producers of the shows that make reality television," Worman said.


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How will texting-while-driving ban affect Grindr? Johnson says it could lead to racial profiling
Eric Johnson In case you missed it, the Texas House on Thursday passed a bill that would ban texting while driving and make it punishable by a fine of up to $200. The bill was amended so that it would not prohibit reading text messages, just typing them. And motorists would even be allowed to type messages so long as they're at stop signs or red lights. Naturally our first question was — how will this affect Grindr? — because we all know it's during those long road trips when the gay mobile app is at its most useful. But seriously, this proposal, which now goes to the Senate, does sound a little difficult to enforce. For example, how does the officer know whether you're typing a message or just reading one? State Rep. Eric Johnson, D-Dallas, apparently shares these concerns (but not the one about Grindr). Johnson sent out a press release today announcing that he voted against the proposed ban: "HB 243 is crafted in a way that will be very difficult for police to fairly enforce. It is almost impossible to distinguish between a driver writing or sending a text message, which is prohibited in the bill, and a driver reading a text message, dialing a phone number, or reading a Google map, all of which remain permissible under HB 243," said Rep. Johnson. "HB 243...Read More


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Given how critical the tail rotor is to basic helicopter flight, it is difficult to believe that ground-breaking NASA research on tail-rotor effectiveness (and the loss thereof) could languish in a filing cabinet at the Langley research center for nearly two decades. But it happened.
The Vietnam War was the impetus for the project, where Bell UH-1 Hueys were found lacking tail-rotor effectiveness at critical moments, and the U.S. military tasked NASA with finding a solution. Yet when the war ended, the military's urgency to find a solution to loss of tail rotor effectiveness (LTE) went away and the research sat dormant in a folder.
The material was unearthed in 1998 by Robert Desroche, founder and owner of BLR Aerospace of Everett, Wash., an aerodynamicist and a pilot. And that's how BLR's Fastfin STC was developed. Desroche, whose company holds numerous patents, read a paper written by Henry Kelley, principal researcher on the tail-rotor augmentation project and decided that the research was worth pursuing.
"NASA has a privatization program whereby technologies originally patented by NASA can be made available to U.S. taxpayers through a licensing agreement," explained Dave Marone, vice president, sales and marketing for BLR. "What BLR did was take the product as conceptualized by Henry Kelley and his team at NASA and put it through extensive flight testing and refinement to make it into a product that could be commercialized and STC'd for aircraft."
That's how Fastfin was developed. The dual tailboom strakes originally patented by Kelley were mated to a unique, sculpted vertical fin designed by Desroche, which allows for the sail area necessary for weathercock stability of the aircraft without having an undesirable physical impediment to the airflow.
Now, regardless of what direction the wind is coming from, the pilot gets a managed laminar flow over the tailboom, instead of a disrupted, inefficient flow. "The Fastfin-equipped helicopter's off-wind performance compared to a stock Bell 412, for instance, is a night and day experience," explained Marone. Fastfin is STC'd for Bell 204, 205, UH-1, 212 and 412 aircraft.
The safety enhancements of Fastfin would be reason enough to apply the STC, but with better aerodynamic performance come other desirable results, namely, increased performance. "Depending on the weight of the aircraft and the operating altitude, the fuel savings will be 2.5 to 6.5 percent while in the hover [not in forward flight]," said Marone, referring to the Bell 412 with the Fastfin mod.
"Along with that we can increase useable operational loads," he said. In this case we are improving yaw control [permitting an increase in useful load] in the neighborhood of 12 percent and 12 percent of 11,900 lbs is about 91 percent of its [previous] operationally useful load at that altitude. That is the logic."
Marone reported at Heli-Expo 2012 that the company has sold nearly 100 Fastfin mods for the Bell helicopters since it was certified in December of 2010. Those who would like to learn more about the engineering technology that went into the STC can meet Henry Kelley at the BLR Aerospace booth (No. 8846) in Exhibit Hall F.
Carlos Ordonez (not verified)
February 15, 2012 - 10:04pm
If you are considering buying another aircraft because of the limitations of useful load at high density altitudes, you could save 10 times your ne investment by installing a FastFin system
R.KOTTAIYANNAN (not verified)
April 10, 2012 - 8:50pm
very interating to study and seeing


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Three Decades of Super Bowl Halftime Style
Janet Jackson's great wardrobe malfunction of 2004 is forever lodged in our brains. But what about halftime history's other, more random fashion moments? We've rounded up a few, from a lamé-clad '80s Elvis impersonator to last year's guy in a dress. Fumbles? Tackles? You decide.--Beth Greenfield, Yahoo! Shine Staff


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Eat up 'em up pretty quick or refrigerate them though - I'm not too sure how well they will hold up on the countertop. Just treat 'em like you would banana bread.
Anyway, these are super soft coming out of the oven so I do highly recommend using parchment paper cuz otherwise they tend to want to stick, yes, even to non-stick cookie sheets. Let them cool on the parchment paper long enough to firm up a bit before transferring them onto a cooling rack to cool completely. Once they are fully cooled, they'll firm up a bit, but expect a softer, more cake-like cookie from this recipe. (And there's another one of those 70s dishes again! Groovy.)
Banana Oatmeal Chocolate Chip Cookies
From the Kitchen of Deep South Dish
1 egg, beaten
3 ripe bananas, mashed
1-1/2 cups of White Lily all purpose flour
1/2 teaspoon baking soda
1 teaspoon salt
1-3/4 cup Quaker Old Fashioned oatmeal
1 cup sugar
1 teaspoon cinnamon
1/4 teaspoon nutmeg
3/4 cup Crisco shortening
1/2 cup of chocolate chips
Preheat oven to 400 degrees. In a small bowl, beat the egg and banana together. In a mixing bowl, whisk together the flour, baking soda, and salt; add the oatmeal, sugar, cinnamon, nutmeg and turn on the mixer. Add the egg and banana mixture and mix. Beat in the shortening. Remove from the mixer and stir in the chocolate chips. Using a small or medium cookie scoop, scoop dough onto parchment paper on a cookie sheet and bake at 400 degrees for 12 to 15 minutes. Store in refrigerator.
Makes about 4 dozen.
Click here for the basic Hot Chocolate recipe, or try some rich and decadent Italian Hot Chocolate.
Source: http://deepsouthdish.com
Requires Adobe Reader - download it free!
Adapted from Betty Crocker's Cooky Book 1963
Check These Out Too!
Chocolate Chocolate Chip Caramel Bars
My Favorite Chocolate Chip Cookie
Mama's Pecan Finger Cookies


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Posted 5 years ago
(136 items)
I love this tunic. Unfortunately, it is unidentified, however, the ribbon bars for this brave Sailor speak for itself! Purple Heart, Good Conduct, American Defense, Navy Unit Commendation, American Campaign, Presidential Unit Citation with star (awarded to the Sailor twice), Asian - Pacific Campaign Medal with 3 combat stars, and the WWII Victory ribbon.
On the right chest is the "Ruptured Duck" patch, meaning that this Sailor was Honorably discharged after the war. The left sleeve has a US Naval Amphibious Forces patch, and the rank of Petty Officer First Class Hospital Corpsman.
The silk scarf is not WWII era, its just an extra one I had that was issued to me when I was in the Navy. Great uniform grouping, and I can not imagine the blood & guts this Sailor was witness to, while patching up wounded young Marines. Keep in mind, Navy Corpsmen were usually unarmed!! They ran through a hail of gun fire & explosions to the sound of "CORPSMAN!!!!!" One of the most DANGEROUS jobs on the battle field, and EVERY Marines best friend! Any Marine would go out of his way to protect the Corpsman, because with out the Corpsman, the Marines KNEW they were doomed if they became wounded.....


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Adobe® Media Server 5 software helps premium content publishers deliver their HD quality video to the largest audience possible across any Internet-connected device, with a streamlined workflow. The Adobe Media Server family revolutionizes media delivery with support for consistent, protected streaming on the widest array of devices — tablets, mobile devices, connected TVs, and desktops.
Target the widest array of devices such as iOS and Android™ smartphones and tablets, Internet-connected TVs, and desktops with a single streaming platform.
Enjoy HD streaming at 1080p for live and on-demand video using industry-standard technologies.
Create rich social experiences that keep your customers watching your videos longer.
Access a wide range of deployment options that allow flexible strategies for managing load spikes, eliminating points of failure, and reducing delivery costs.
Lock down your audio and video streams with dynamic media encryption.
Leading video-on-demand portal delivers seamless, high-quality experiences to audiences across Russia using Adobe Flash Media Server 4.5 and Adobe Flash Access software
Online video service Voddler utilizes the Adobe® Flash® Platform, including the Adobe AIR® runtime and Adobe Access software, to protect and monetize streaming video content.
Midwestern university integrates online video into teaching, learning, research, and administration on an enterprise scale using Adobe Flash technology.


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BEING SELLERS Comes To Brits Off Broadway at 59E59 Theaters
59E59 Theaters (Elysabeth Kleinhans, Artistic Director; Peter Tear, Executive Producer) welcomes the Waterloo East Theatre to the 2010 Brits Off Broadway festival with the US premiere of BEING SELLERS, written by Carl Caulfield, directed by Simon Green and starring David Boyle as Peter Sellers. BEING SELLERS begins performances on Tuesday, November 23 for a limited engagement through Sunday, December 12. Press opening is Sunday, November 28 at 7:30 PM. The performance schedule is Tuesday & Wednesday at 7:30 PM; Thursday & Friday at 8:30 PM; Saturday at 2:30 PM and 8:30 PM; and Sunday at 3:30 PM and 7:30 PM. Tickets are $25 ($17.50 for 59E59 Members). To purchase tickets, call Ticket Central at (212) 279-4200 or go to www.59e59.org. For more information, visit www.britsoffbroadway.com.
Peter Sellers was celebrated for his ability to transform himself completely into his characters-from Chief Inspector Clouseau to Doctor Strangelove-but who was he and what was the personal cost of his comic genius? Marking the 30th anniversary of Sellers' death, Carl Caulfield's poignant comedy is an endearing portrait of one of the 20th Century's most iconic, admired and adored actor/comedians. BEING SELLERS comes to Brits Off Broadway direct from its run at London's new Off West End venue, the Waterloo East Theatre (November 2 - 19).
Carl Caulfield (playwright) has spent his life in the theater as playwright, director, dramaturg, and actor. For 20 years, he lived in Australia where he was a Lecturer in Drama at the University of Newcastle and was a co-director; with his wife Felicity Biggins, of Stray Dogs Theatre Company. He recently returned to the UK and is now Senior Lecturer in Dramatic Scriptwriting at Edge Hill University. His plays include: Indecent Obsessions, Dante's Dream, Human Resources, The True Phoenix, The Caper, Shakespeare's Fools and The Mystery of Roger Mullaney which was recently published by Macmillan. His new play, 2039, a dystopian thriller, will be produced by Tantrum Youth Theatre in Newcastle in November. In July 2007, Carl was a guest playwright at the prestigious Eugene O'Neill Theater Center in Connecticut where he also mentored young professionals in Playwriting and Direction. He was also a guest playwright/dramaturg of the Kennedy Center American Theatre College Festival (KCACTF) in North Carolina, Greensboro in February 2008. Being Sellers was first produced in 1998 by Civic Theatre Newcastle before going to the Edinburgh Fringe Festival and then transferring to Man In The Moon Theatre, London. Carl is delighted that David Boyle reprised the play at Waterloo East Theatre London and now has the opportunity to play it again at Brits Off Broadway.
For Brits Off Broadway at 59E59 Theaters Simon Green (director) directed Cooking For Kings (2006 & 2004), Beau Brummel, Fascinating Aïda in Absolutely Fascinating (also at the Kirk Theater - Drama Desk nomination) and was the consulting director for The Hired Man. Other directing credits include: An Ideal Husband (English Theatre Frankfurt); at Cadogan Hall, Sing For Your Supper, Good Thing Going - A Sondheim Celebration with the Royal Philharmonic Orchestra and A Swell Party; at Salisbury Playhouse, Let's Face The Music And Dance, The Way You Look Tonight and later this year With A Song In My Heart. In the West End he was the associate director of Auntie and Me starring Alan Davies and Margaret Tyzack (Wyndham's). Other plays include Split (Stephen Joseph Theatre, Scarborough), Time Of My Life (Bristol Old Vic) and for Cameron Macintosh he was the resident director of Phantom of the Opera (Manchester Opera House). As an actor Simon's many London and West End appearances include Jules in Sunday in the Park With George, (Menier Chocolate Factory and Wyndham's), Torasso in Passion (Queen's) and Young Ben in Follies (Shaftesbury), The Knight of the Burning Pestle (Barbican), Lumiere in Disney's Beauty and the Beast (Dominion), La Cenerentola (Drill Hall), March of the Falsettos (Albery), Elegies (Criterion), Coriolanus (Young Vic) Elmer Gantry (Gate), The Scarlet Pimpernel (Her Majesty's), Lady Be Good (Regent's Park and national tour), The Boyfriend (Old Vic & Albery), for the RSC The Wizard of Oz (Stratford and Barbican) and Showboat (Palladium). Also at 59E59 Theaters Simon has performed Coward at Christmas and Traveling Light (2010 Drama Desk Award nomination for Outstanding Musical Revue).


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A 2 Part, Phase 2 Trial of Galeterone in the Treatment of Castration Resistant Prostate Cancer (ARMOR2)
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|Prostate Cancer
|Drug: galeterone
|Phase 2
|Study Type:
|Study Design:
|Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
|Official Title:
|ARMOR2: A 2 Part, Phase 2 Trial of Galeterone in the Treatment of Castration Resistant Prostate Cancer
- Confirmation of recommended dose and patient population for Part 2 of the study. [ Time Frame: 3 months ]
- Assessment of efficacy by means of PSA response. [ Time Frame: 3 months ]
|Study Start Date:
|December 2012
|Estimated Study Completion Date:
|August 2017
|Primary Completion Date:
|September 2016 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: Dose Confirmation
Dose A - galeterone tablets once daily PO for three months + extension
Dose B - galeterone tablets once daily PO for three months + extension
Dose C - galeterone tablets once daily PO for three months + extension
Drug: galeterone
Other Name: TOK-001
Experimental: Dose Expansion
Single dose expansion (from part 1) of galeterone tablets once daily PO for three months + extension
Drug: galeterone
Other Name: TOK-001
Detailed Description:
This trial will be split into two parts. The purpose of Part 1 will be to confirm dose and target patient population and Part 2 will be expansion of the dose and patient population selected in Part 1. For eligible patients, there will be an optional extension dosing following the completion of Part 1 or Part 2 of the trial.
Obtaining of informed consent and screening may be performed up to 28 days prior to enrollment. Each patient will be able to receive his specified regimen for 3 consecutive cycles. Each cycle consists of 28 days (approximately 1 mo.). End of Cycle 3 visit assessments will be used to determine outcome and dosing may continue up to an additional 2 weeks until the results of all assessments are obtained. Eligible patients may continue treatment in an optional extension period following the completion of the primary parts of this trial.
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Histologically or cytologically confirmed adenocarcinoma of the prostate
- Ongoing androgen blockade demonstrated by serum testosterone concentration of less than 50 ng/dL
- Demonstration of progression while on androgen blockade
- Eastern Cooperative Oncology Group (ECOG) Performance Status <2
Exclusion Criteria:
Depending upon patient prior treatment the following apply:
- Prior treatment with CYP17 inhibitors or AR antagonists (e.g. abiraterone, TAK-700, ARN-509, ketoconazole*, enzalutamide, or galeterone) - Treatment naïve only
- Prior treatment with CYP17 inhibitors (e.g. TAK-700, ketoconazole*) or AR antagonists (e.g. enzalutamide, ARN-509,) or galeterone - abiraterone refractory only
- Prior treatment with CYP17 inhibitors (e.g. abiraterone, TAK-700, ketoconazole*) or AR antagonists (e.g. ARN -509) or galeterone - enzalutamide refractory only
- Prior chemotherapy (unless allowed for some study arms)
- Treatment with non-steroidal oral antiandrogens within 4 weeks of enrollment
- Prior use of any chronic systemic glucocorticoids .
- Prior radiation therapy within 3 weeks and radionuclide therapy within 8 weeks of enrollment
- Prior treatment with Alpharadin® (Xofigo®)
- Treatment with anti arrhythmia therapy for ventricular arrhythmia < 4 weeks prior to enrollment
- Treatment with Coumadin® or other anti-coagulant therapy (except aspirin) < 4 weeks prior to enrollment
- Severe systemic diseases or active uncontrolled illnesses.
- Abnormal heart function
- Liver metastases
- Brain metastases (unless stable disease >3 mos. by scan without additional CNS-directed therapy)
- The patient has known allergy to any of the treatment components
- Any physical or mental condition or social situation that in the opinion of the Investigator may interfere with the patient's ability to comply with the trial procedures
- History of excessive alcohol consumption
- Use of any substance known to cause AME
Please refer to this study by its ClinicalTrials.gov identifier: NCT01709734
Show 23 Study Locations
|Principal Investigator:
|Bruce Montgomery, M.D.
|University of Washington/Seattle Cancer Care Alliance
|Principal Investigator:
|Mary Ellen Taplin, M.D.
|Dana-Farber Cancer Institute
|Responsible Party:
|Novus Therapeutics, Inc
|ClinicalTrials.gov Identifier:
|NCT01709734 History of Changes
|Other Study ID Numbers:
|Study First Received:
|October 16, 2012
|Last Updated:
|August 8, 2017
Keywords provided by Novus Therapeutics, Inc:
prostate cancer CRPC
Additional relevant MeSH terms:
Prostatic Neoplasms
Genital Neoplasms, Male
Urogenital Neoplasms
Neoplasms by Site
Genital Diseases, Male
Prostatic Diseases
ClinicalTrials.gov processed this record on September 19, 2017


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Energy Price Outlook
The deja vu trade appears likely to remain in tact in the near-term, as recently attained bullish momentum was undercut in yesterday's trade. The resulting sideways trend will oscillate between moments of euphoria and doubt, which may essentially feel like a repeat of the decisive rallies and selloffs of the last few weeks which were believed to be the beginnings of new breakouts and breakdowns. Recent bullish momentum had been sparked by improved economic data in China and Europe, weakness in the dollar, accommodative Fed policy, and recent oil production declines by Saudi Arabia. Those were undercut yesterday by weak German GDP, a potential downgrade of the U.S. debt rating, and comments from EU's Juncker who said that the euro is dangerously high. The bottom line between these ups and downs is that the market has almost gone nowhere in Brent and slightly higher in WTI. Expecting that trend to continue may be the best assumption going forward. We favor holding our June WTI-Brent trade entered on Jan 4th at -$14.25 with a target at -$8.00. In the event of a selloff in WTI, we would look for a rebound after a test of the $91.50 level. We would also anticipate a shrinking of the WTI futures contango. APIs were a bit bullish yesterday afternoon.
WTI futures settled 86 cents lower yesterday while Brent finished down $1.58. The Feb Brent futures make their last trade today. At the start of the session yesterday, some support was provided by another gain in China's Shanghai Composite and a report that China's power consumption could rise 9%-10% this year compared to 5.5% last year (chart). The sense that China's economy bottomed last August along with the HSBC PMI level has been a primary driver of the oil price rally recently, as imports from the country have been firm as well. China's implied demand figures reached 10.50 mb/d in Nov, which was a new record high. The small overnight rally reversed when the euro currency turned lower following Germany's reported preliminary 2012 GDP figure at just +0.7% compared to 2011's +3.0% and 2010's 4.2%. The euro fell despite Fitch reporting that Spain may not activate the OMT at all in 2013. Further pressure was added late in the session by EU's Juncker who said that the euro exchange rate is dangerously high.
Additionally two-sided were developments from the Fed, which embarked on a grand new QE program only to undercut it in the FOMC minutes by saying that policy could be tightened before its 2015 target. Dovish Fed presidents have recently voiced concern about the effects of the growing Fed balance sheet even though they were in favor of the action a couple months ago. Saudi Arabia has done something similar by reducing output nearly 1.0 mb/d to 19 month lows at 9.025 mb/d. That was interpreted as an attempt to boost prices to maintain social programs in the country, but Saudi Arabia clarified that on Monday to suggest it was just preventing an inventory buildup during a seasonally weak period of demand.
Natural Gas
February futures finished 8.2 cents higher yesterday amid strength in the front-end of the curve. The focus again was on colder temperatures that are predicted to make their way across the Midwest and Eastern portions of the country between Jan 20th-24th. Low temperatures in Chicago are forecast to reach 5 degrees during that time. The updated 6-10 day showed a higher probability of cold in the northeastern portion of the country, although the 8-14 day was generally similar. A key question though will be whether this bout of cold weather is a new norm or only a temporary event. Forecasts in several Midwest cities show much warmer temps both before and after the cold spell next week. The market may have to wait for Thursday's long-term update from the Climate Prediction Center for more clarity. In its last report, it showed temps in January that were above-normal across the eastern two-thirds of the country. The 2-4 day cold spell next week may not be enough to substantially reduce stocks of natural gas unless it were to linger.
Prices have rallied more than 40 cents off the Jan 2nd low at $3.05 in the last two weeks. The rally looks impressive on the chart, but there are still clouds on the horizon for the uptrend. There is strong resistance from Dec 21st high at $3.532 as well as from the 50-day MA at $3.56. The market also hasn't seen an accompanying increase in open interest or a notable liquidation in the net-short currently held by non-commercials and managed money accounts. Pressure could also come from potential increases in production as signaled by gains in rig counts since the w/e Nov 2nd. Our forecast for inventories this week is a draw of 129 bcf which would compare to the five-year average decline of 144 bcf. Our end-of-season forecast is 2068 bcf and compares to the five-year average of 1714. The bottom line is that even with short bouts of below-normal temperatures, inventories are on tap to end the withdrawal season with above-normal stock levels. We'd look for potential bearish action close to the $3.53 resistance level this week to think about a possible short position.
Global Economic & Dollar News
» China's Power Consumption may rise 9%-10% this year, which is faster than 2012's 5.5% growth.
» China's Gov't has pulled government automobiles off the road and closed dozens of factories in order to cut down on record-setting pollution levels.
» China's Gov't told the PLA to prepare for war in 2013. Japan wasn't mentioned but is likely the target, as the two countries have territorial disputes over the Diaoyutai islands.
» Germany GDP was -2.0% in Q4. The full-year 2012 preliminary figure was +0.7% vs. +0.8% expected. That also compared to +3.0% in 2011 and +4.2% in 2010.
» Spain may not activate the OMT in 2013, according to Fitch.
» The Debt Ceiling may be raised for four years based on a deal that would get republicans major tax and entitlement changes, according to Roll Call.
» Fitch said that it will launch a review of the U.S. credit rating if the debt ceiling isn't raised in a timely fashion.
» Empire State MFG Index was -7.78 vs. unchanged expected and vs. -7.30 previously.
» U.S. PPI was -0.2% vs. -0.1% expected. Core PPI was +0.1% vs. +0.2% expected.
» Retail Sales were +0.5% vs. +0.2% expected while sales ex-autos were +0.3% vs. +0.2% expected.
» National Retail Federation said that holiday sales were +3.0% vs. +4.1% expected. It was the lowest gain since 2009.
» EU's Juncker said that the euro exchange rate is dangerously high.
Energy News
» Morgan Stanley reduced its 2013 natural gas price forecast to $3.50/mmbtu from $3.90 due to warm weather.
» The CME clarified its ULSD heating oil contract to say that the specification will change to Colonial 62-grade with the May 2013 contract.
» Phillips 66 Wood River Refinery returned its crude unit to service at its 356 kb/d facility after an electrical fire on Jan 12th.
Upcoming Events
Wed - Iran-IAEA Meeting
Wed - EIA Weekly Oil Inventories (10:30am EST)
Thu - IEA's Monthly Report
Thu - CPC Monthly Weather Update
Thu - Natural Gas Inventories (10:30am EST)
Sun - German Local Election
Tue - Israeli Election
Tue - Last Trade CLG3
Tue - API Inventories (4:30pm EST)
Jan 29-30 - FOMC Meeting
Feb 12th - EIA's Short-Term Outlook
Feb 24-25 - Italian election
Mar 1st - Sequester Begins
Mar 14th - Debt Ceiling
May 31st - OPEC Meeting
EIA Inventory Preview
The oil stocks number this week may reflect a more decisive change in direction from recent weeks where oil stocks fell sharply and products witnessed strong increases. Oil stocks typically gain throughout the first five months of the year after liquidations take place in December. If that's indeed the case again this year, oil stocks could witness a larger increase than that suggested by the five-year average as late-2012 conditions unwind. An 11.1 MB drawdown was reported in the last week of December and reflected refineries' intentions to convert raw crude into products. A slowdown in utilization coupled with high levels of imports should create an above-average increase this week. Cushing stocks could increase again this week, as the Seaway pipeline was closed for part of the week in front of Friday's ramp-up. Cushing should level off or begin to fall with next week's data.
Gasoline inventories have gained 10.0 MB in the last two weeks while distillates increased 11.4 MB. High levels of utilization have been partly to blame and should begin to pull back a bit this week, in our view. Lower levels of production should add pressure to stocks, but demand has been weak as well and may prevent a drawdown. Distillate stocks have benefitted from higher production and weak demand but may receive pressure this week from lower production and continued exports.
Natural gas inventories are expected to be -129 bcf. NOAA's HDD calculations were between 179 and 199, which compares to the previous week's 238. Last week's draw of 201 bcf was at the larger end of the consensus range, and was a bit higher than our model had predicted. There could be a small amount of retrenchment in this week's figure as a result. Temperatures were above-normal in the northern Great Plains during the survey week and may help to dampen the withdrawal. The east coast saw near-normal temperatures.
*The API convergence figures are the amounts that EIA data need to change in order to match the previous day's API figures
Grains Commentary
Published Tuesday morning, 1/15/12
The overnight markets once again give a little for everyone as decent swings were seen throughout the evening session. The beans have rallied nearly $1 since last Friday and they had the least impact from the USDA while corn has gained only 40 cents. So what should be done now?
The market knows that its job now is to ration demand somehow someway in both beans and corn but with profitable margins in nearly every corner it's difficult to see where the rationing will take place anytime soon. The poultry and hog markets are profitable for corn, the ethanol margin has improved over the past few weeks (still negative but improving, the new crop margin is already profitable) the export markets are still stagnant which at this point is a blessing. If the US becomes competitive in the export arena for corn then the candle might be lit for a run back to contract highs. The beans continue to do more business than is needed and with articles being blasted out everywhere showing how good the Chinese crush margins are its difficult to see this pattern slowing anytime soon. It's well known that SA will have massive crops but the logistics could still be a bigger problem or hindrance. The only change that has started to take place over the past 5 days is the US crush margins are falling; the March is down nearly 10 cents while the January calculated out at a negative.
The Argentine weather is starting to get some attention as it is warm and turning drier, we would like to point out that just 3 weeks ago we were discussing the fear of acreage lost to too much rain. The overall crop status is still very good and yes maybe Argentina won't produce a 55.0mt bean crop or a 27.0mt corn crop but even taking 10% off of both does change the fact that SA will still have a record production season. The US weather will start to get more attention in coming weeks again and this is more of a concern than SA as dry areas still have not had enough moisture this winter, keep a close eye on this as this could create for some dynamic market activity in coming months. Trade will not wait to see on this, there will be tremendous volatility if weather is even slightly off from normal.
The outside markets are mixed with little significant movement. The DCE closed higher in all markets, the Matif is higher and MDEX is higher.
There was 225 bean deliveries last night by ADM, it's somewhat ironic that they delivered on the last trading day, it's apparent that they really didn't want to deliver anything but even more so they didn't want to pay +50 to buy it back.
The OI in corn fell by 1133, wheat was up 588, beans were down 460, meal increased by 4516 (index purchases is over) oil increased by 528.
The option markets have quickly sucked out the entire premium that was there before the report and is now down to levels that could be worth owning again. The CH is down to 21% with 38 days left and look at the spreads recently; it's all old crop movement. The SH eased to under 20% again, just look at the price activity over the past 48 hours, the flat price has moved more than the entire value of the straddle. The downside bean put skews still have a slight positive slant but not as attractive as last week. The WH remains in the mid 20's and may look high when compared to corn but wheat has the tendency to have some volatile moves during the month of February.


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Having detailed the potential drag on consumer spending from the end of the payroll tax cut, one might wonder about the performance of the overall economy. The Chicago Fed released the results of its most recent Economic Outlook Symposium (PDF) on Thursday, summarizing the economists' views for 2013. The consensus is for the economy to continue growing moderately, roughly in line with its long-term potential. (Recall that potential GDP growth is determined by growth of the labor force plus productivity gains, which works out to about 2.5%.) The economy needs to grow faster than this to bring down unemployment significantly.
But with the economists' forecast of 2.3% growth in GDP in 2013, even though it's a bit better than 2012's projected 1.7% increase, job growth may only keep up with population growth. We might not be able to put the 12.2 million people who are officially unemployed back to work, plus the 1.1 million people who have given up their job search but still want a job. That means that the economists expect unemployment at the end of 2013 to be 7.6% -- not much different from the current 7.8%.
Even so, these economists project consumer spending to increase by 2.3%, an improvement from this year's projected 2% spending growth. I might be a bit more cautious due to the end of the payroll tax cut. First, a forecast for an increase in spending growth relies on some combination of either wage growth accelerating, more people working, the savings rate decreasing, or consumers receiving cash flow from other activities, such as investment sales or income.
What we see now is that the savings rate is 3.6%, a low level, given historical rates are more than double this amount, not to mention consumers' need to save for retirement. I might surmise that consumers might be wary about saving less, focusing more on wage growth to fuel an increase in their spending. Last year, aggregate weekly payrolls, a measure of what people earned on the job, increased by 4.2% in nominal (not inflation-adjusted) terms. (This is a function of more people working, working more hours and earning more per hour.) Based on the economists' forecasts for employment trends, we might reasonably expect this year to be a bit better than 2012 for wage growth.
Subtracting some amount for inflation, which forecasters believe will be 2.1% this year for the Consumer Price Index, we might arrive at about that forecast rate of increase for consumer spending. But what about the end of the payroll tax cut? Based on consumers' so-called "marginal propensity to consume" funds they will no longer have from the end of the payroll tax cut, that may reduce consumer spending by 1% from what it would be otherwise. That means consumer spending may come in weaker than the economists forecast, perhaps in the 1.5% range, give or take. Of course, consumers also derive income from other sources, or they might reduce their savings rate further as confidence from rising home prices causes them to spend more.
Meanwhile, the economists expect business fixed investment (property, plant and equipment) to increase by 3.5% this year, up from 2.5% in 2012. But we still have debates on government spending coming up, as recent legislation only dealt with the tax side of the budget equation. Businesses might wait for a full budget proposal and the other side of the trio of Congressional debates in the next couple of months on the debt ceiling, spending cuts and funding the federal government. These forecasts for government spending to contract by only 0.4% may understate the likely government spending cuts, leading to more optimism than is warranted on business investment.
Even with all that caution, there's reason for optimism. First, it's easy to believe consumers will buy more cars given the average age of cars is at a record high. We might see 15 million new cars sold this year, up from 14.3 million projected for 2012. Housing starts are projected to climb to 0.95 million this year from 770,000 in 2012, with real residential investment to increase by 9.4% in 2013.
All these data lead to forecasts for industrial production to increase by 2.7%, up from 2.3% last year. Economic growth is expected to improve over the course of the year, with GDP rising to 2.7% in the fourth from 2% in the first quarter.
Thus, while Washington's output may hinder the nation's economic output a bit, there is still ample reason to believe the economy may continue to grow at a moderate pace. Unfortunately, that won't be enough to bring down unemployment significantly.


text: This news item expired on 9/5/2013, so the information below could be outdated or incorrect. East Asheville Book Club: The Casual Vacancy Thursday, September 5 at 6:30pm East Asheville Library 902 Tunnel Road 250-4738 The book to be discussed is "The Casual Vacancy" by J.K. Rowling. All interested readers are welcome to attend.


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Republicans were handed a convincing defeat at the polls, not only losing the race for the presidency but also losing ground in the Senate. The good news for the country is that Republican leadership is not in denial. The day after the election, Speaker of the House John Boehner outlined a balanced approach for easing federal policy off the fiscal cliff. He offered a combination of revenue increases and spending cuts, with an emphasis on "real changes to the structure of entitlement programs."
Two days later, President Barack Obama responded by offering his own balanced approach—more federal spending, lower taxes for everyone but the wealthy, and the certainty of much higher budget deficits for years to come unless the savings proposed by the president last February actually materialize. This draws the line where it was before the election, with no sign that this will lead to meaningful policy negotiations.
This seeming recalcitrance is likely the result of the irrational exuberance that often strikes newly elected officials. To paraphrase Alan Greenspan, irrational exuberance has unduly escalated the president's political asset value. Contrary to his current stance, President Obama does not have a strong hand in the upcoming fiscal debate. If he wants to avoid a double-dip recession and leave a positive legacy, he will have to accept compromises and sell them to his Democratic colleagues in the Senate. That inevitably means health policy, including the Affordable Care Act (ACA), will be on the negotiating table.
In one sense the Administration is already negotiating with itself over provisions of the ACA. On November 9, the Department of Health and Human Services (HHS) extended the deadline for states to submit plans for setting up their own health insurance exchanges by a month. It has been clear for some time that many states have struggled with the decision to operate their own exchanges or leave it to the federal government. As of October, only 16 states and the District of Columbia (including Massachusetts and Utah, whose efforts predate the ACA) have established a legal basis for an exchange, and even some of the states that made the commitment would not have had specific plans ready for HHS scrutiny in time to meet the original schedule. The ongoing failure to publish many of the regulations required to implement the ACA, opting instead for informal (but legally unenforceable) "guidance" is another admission that legislative requirements are, in fact, malleable and subject to negotiation.
What, then, can we expect from the fiscal deal that will be hammered out over the next year? For health programs, it will certainly not be a "grand bargain."
Medicare. All sides agree that Medicare is a major contributor to our growing federal deficit. The sequester called for by the failure of the "super committee" reduces Medicare spending by 2 percent. The president's 2013 budget doubles the cuts, with $248 billion in savings through 2022. That hardly qualifies as an opening bid, in terms of both money and policy.
That savings amount does not even cover the $271 billion ten-year cost of replacing the scheduled cuts in physicians' fees with a freeze. Policymakers on both sides of the aisle prefer successive brief (one year or less) "fixes" because the budget optics look better even when the full consequences remain the same.
It will be business as usual in this regard next year. The lame duck session of Congress is likely to grant a 3-month reprieve, which keeps physician payment a part of the fiscal cliff negotiations. Short extensions are likely through the year, adding $18.5 billion to the Medicare savings that must be found.
Filling the larger budget hole will force Congress to accept a mix of fee reductions (other than for physicians) and increases in beneficiary costs. Rather than inventing new ways to cut provider payments, the fiscal compromise will probably accelerate implementation of the "productivity adjustments" and other fee-reduction provisions imposed by the ACA. Medicare premiums are likely to rise (perhaps to an average of 35 percent of the cost of Part B and Part D), with more of the cost paid by higher-income beneficiaries.
Other initiatives are more speculative but possible. Medicare could shed its historical division into Part A and Part B, which no longer has any usefulness (if it ever did). Combining Medicare's parts into a single comprehensive health benefit would allow restructuring the complex cost-sharing requirements that currently exist, and which make no sense. A single all-encompassing deductible, a simple uniform copayment or coinsurance structure across all services, and the addition of a cap on catastrophic expenses would convert the program into modern insurance. The Part B premium would become a premium for the entire benefit with appropriate adjustment to the rate to avoid overburdening beneficiaries. A surcharge could be imposed on supplemental coverage (Medigap and retiree plans) to recoup some of the extra cost imposed on the program when cost-sharing requirements are largely paid by the additional insurance.
These are stop-gap measures at best. Structural reforms that shift Medicare from an open-ended entitlement to a budgeted approach are needed. Financial incentives must shift from fee-for-service to more sophisticated payment methods that promote innovative approaches to health care delivery. Such reforms could reduce the total cost of care, not just the federal government's share.
The ACA places an overall cap on the growth of federal Medicare spending that is enforced by the Independent Payment Advisory Board (IPAB)—ironically, a likely casualty of the fiscal deal that will be struck next year. The IPAB is unpopular with anyone who is or who might be chair of the key congressional committees that traditionally set Medicare policy. Failure to advance any nominations to IPAB reflects a bipartisan dislike of this board.
The alternative approach supported by Republicans is premium support, which remains a viable but dormant political idea. Scare stories about "vouchers" during the campaign did not create a wave of senior backlash against Republicans, but there is also no wave of senior support for major program reforms. For the time being, Congress is likely to adopt more modest reforms intended to improve the competitive bidding process for Medicare Advantage and to give accountable care organizations more control over and accountability for the delivery and cost of their services. Unless President Obama's successor is extraordinarily fortunate, he or she will revisit these issues four plus years from now.
Medicaid. The Medicaid expansion envisioned by the ACA has been short-circuited by the Supreme Court ruling that makes it possible for the states to decide for themselves whether to expand eligibility. Even with more modest take-up by the states, the Medicaid expansion is likely to increase federal spending by $642 billion through 2022.
A fiscal deal would seek to reduce the spending without limiting states' ability to expand Medicaid eligibility. The likely target is the enhanced federal match rate authorized by the ACA, which provides states with full funding for the expansion population for three years. By 2020 the enhanced match tapers down to 90 percent of the cost, which is well above the average amount paid by the federal government for the current Medicaid population. Reducing the enhanced match rates by 10 percentage points would yield about $65 billion in savings over ten years, and perhaps more if the cut induced additional states to refrain from expanding eligibility.
To make the reduction in federal payments more acceptable, Congress might grant broader waiver authority to the Department of Health and Human Services that could allow the states more discretion in how they operate their programs. This would address a central issue in the Republican proposal to provide states with block grants for Medicaid rather than continuing to require them to seek federal permission for even modest changes in states' policies and management procedures.
Private Insurance and Exchanges. The largest category of new spending created by the ACA is the subsidy for insurance offered on the exchanges, totaling $1 trillion through 2022. The administration would be reluctant to modify the subsidy structure, particularly if they believe that the Supreme Court's decision to make the insurance mandate a tax significantly weakens the pressure on individuals to purchase coverage. They might reason that a generous subsidy is needed under that circumstance to maintain a stable insurance market.
Nonetheless, reducing the subsidy (perhaps by cutting its generosity and limiting its availability to individuals with incomes below 250 percent of poverty rather than the current 400 percent) offers substantial budget savings. Those savings may be easier for the public to accept than cuts in existing programs that already have well-established and politically vocal constituents.
An alternative would be to delay implementing the exchanges and the subsidy. That is likely to be unavoidable in some states, and a fiscal deal could get credit for what might be inevitable. Numerous states are unlikely to have insurance exchanges running by October 2013, and there is some question about the ability of the federal government to create a functioning replacement. Important regulations defining how the exchanges are expected to operate have not been issued, and the political and technical challenges of creating a complex insurance market based on almost no experience are sufficient to create significant delays in many states—including states headed by Democrats.
A less likely alternative but one with greater leverage on the health system is a reform of the tax subsidy for employer-sponsored insurance. The ACA includes a "Cadillac tax" on employer coverage deemed too expensive. The administration has agreed that our current tax subsidy is inefficient even though they endorsed an inefficient way to address this problem. The tax is imposed on insurers, but obviously most of it will be passed on to workers in the form of higher premiums who will receive a tax subsidy on the higher amount. The political objective was to avoid admitting that the tax would be paid by those who will, in fact, pay it. Broad tax reform could make sense out of this by directly limiting the amount of insurance premium that can be excluded from personal income tax.
Health Care Has Its Own Cliff. We can be confident that Congress and the president will find a way to bridge their differences enough to ease the country off of the fiscal cliff. Some combination of policies that slow the growth of federal spending and increase the flow of federal revenue will be agreed to by the end of next year, although not likely much before that.
Health programs, which account for about 25 percent of the federal budget, will figure prominently in resolving the immediate fiscal problem. The legislation will depend heavily on reductions in Medicare fees, which yield scoreable budget savings but do little to change the financial incentives driving program spending and growth in national health spending. Without structural reform, federal health programs—particularly Medicare—will remain on the precipice.


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MONTREAL Mega Brands announced that it has secured a worldwide agreement with Ludorum, to produce a range of Chuggington construction toys under its Mega Bloks brand.
The Chuggington toys will be based on characters from the popular pre-school television series and will launch in most parts of the world from autumn 2011 and the United States from spring 2012, the company reported.
"We are excited to partner with the Ludorum team," said Vic Bertrand, chief innovation officer at Mega Brands. "Chuggington is a great new property that offers engaging characters and tremendous creative building possibilities."


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Get an overview of this hotelFamily-friendly Lisbon hotel in Sete Rios, near Gulbenkian Museum
Popular property highlights
This family-friendly Lisbon hotel is located in the business district, within 1 mi (2 km) of El Corte Ingles Mall and Gulbenkian Museum. Rossio Square and Santa Justa Elevator are also within 3 mi (5 km).
Hotel Features
A full-service spa, a restaurant, and an indoor pool are available at this smoke-free hotel. WiFi in public areas is free. Other amenities include 2 bars/lounges, a 24-hour health club, and a coffee shop/café.
Room Amenities
All 518 soundproofed rooms feature free WiFi and 24-hour room service. For a bit of entertainment, guests will find LCD TVs with satellite channels, and other amenities include minibars and premium bedding.Information missing or incorrect? Tell us!Opens in a new window
Corinthia Hotel Lisbon
Hotel Amenities
Hotel Amenities
In addition to a full-service spa, Corinthia Hotel Lisbon features an indoor pool and a 24-hour health club. Dining options at the hotel include a restaurant and a coffee shop/café. Guests can unwind with a drink at one of hotel's 2 bars/lounges. A computer station is located on site and wireless Internet access is complimentary.
Business-related amenities at this 5-star property consist of a business center and meeting rooms. Event facilities measuring 16146 square feet (1500 square meters) include a conference center. This luxury hotel also offers a children's pool, a sauna, and spa services. For a surcharge, a roundtrip airport shuttle (available on request) is offered to guests. Onsite parking is available (surcharge).
Corinthia Hotel Lisbon is a smoke-free property.
- 24-hour front desk
- Babysitting or childcare (surcharge)
- Airport transportation (surcharge)
- Number of bars/lounges - 2
- Business center
- Breakfast available (surcharge)
- Coffee shop or café
- Concierge services
- Conference space
- 24-hour health club
- Dry cleaning/laundry service
- Elevator/lift
- Express check-in
- Express check-out
- Turkish bath/Hammam
- Gift shops or newsstand
- Free WiFi
- Total number of rooms - 518
- Laundry facilities
- Number of floors - 24
- Meeting rooms 13
- Multilingual staff
- Valet parking (surcharge)
- Terrace
- Porter/bellhop
- Luggage storage
- Restaurant
- Safe-deposit box at front desk
- Conference space size (feet) - 16146
- Self parking (surcharge)
- Shopping on site
- Smoke-free property
- Steam room
- Children's pool
- Wedding services
- Television in common areas
- Free newspapers in lobby
- Full-service spa
- Computer station
- Tours/ticket assistance
- Spa treatment room(s)
- Conference center
- Conference space size (meters) - 1500
- Number of meeting rooms - 13
- Year Built 1981
- Sauna
- Garden
- Number of buildings/towers - 1
- Spa services on site
- Indoor pool
Family Friendly Amenities
- Family Hotel
- Indoor pool
- Children's pool
- Free Wi-Fi
- Soundproofed rooms
- Laundry facilities
- Babysitting or childcare (surcharge)
- In-room childcare (surcharge)
- Cribs/infant beds (complimentary)
Available in all rooms: Free WiFi
Available in some public areas: Free WiFi
Self parking (surcharge), Valet parking (surcharge)
Room Amenities
- Pay movies
- Blackout drapes/curtains
- Air conditioning
- Phone
- Minibar
- Free bottled water
- Daily housekeeping
- Private bathroom
- Free toiletries
- Hair dryer
- Shower only
- In-room childcare (surcharge)
- Iron/ironing board (on request)
- Premium bedding
- Soundproofed rooms
- Satellite TV service
- Free WiFi
- Slippers
- Room service (24 hours)
- Free cribs/infant beds
- Desk
- In-room safe (laptop compatible)
Where to Eat
Buffet breakfasts are available for a surcharge and are served each morning between 7 AM and 10:30 AM.
Sete Colinas - Overlooking the garden, this buffet restaurant serves breakfast only.
Tipico - This fine-dining restaurant serves lunch and dinner. A children's menu is available.
24-hour room service is available.
Nearby Things to Do
An indoor pool and a children's pool are on site. Other recreational amenities include a 24-hour health club and a sauna.
Children under 16 years old are not allowed in the swimming pool, health club, fitness facility, or spa tub without adult supervision.
The recreational activities listed below are available either on site or nearby; fees may apply.
- Bicycle rentals nearby
- Fitness classes on site
Spa Services
Corinthia SPA has 14 treatment rooms including rooms for couples. Services include deep-tissue massages, hot stone massages, sports massages, and Thai massages. A variety of treatment therapies are provided, including aromatherapy, Ayurvedic, and hydrotherapy. The spa is equipped with a sauna, a spa tub, a steam room, and Turkish bath/hammam.
The spa is open daily. Children under 16 years old are not allowed in the spa without adult supervision.
- Hot stone massage
- Deep tissue massage
- Steam room in spa
- Thai massage
- Sports massage
- Ayurvedic treatments
- Aromatherapy treatments
- Spa tub in spa
- Massages
- Number of treatment rooms 14
- Couples treatment rooms
- Body wraps
- Body scrubs
- Sauna in spa
- Hydrotherapy treatments
- Body treatments
- Facial treatments
If you have requests for specific accessibility needs, please note them at check-out when you book your room.
- Roll-in shower
- In-room accessibility
- Accessible bathroom
Hotel Policies
Minimum check-in age is 18
Check-in time starts at 2 PM
Special check-in instructions:
Check-out time is noon
Payment types
Children and extra beds
- Children are welcome.
- Kids stay free! One child 12 years old or younger stays free when using existing bedding.
- Rollaway/extra beds are available for EUR 70 per night.
- Free cribs (infant beds)!
- Pets not allowed
You need to know
Extra-person charges may apply and vary depending on property policy.
- Deposit: EUR 100.00 per stay
- New Year's Eve (31 December) Gala Dinner per adult: EUR 195.00
- New Year's Eve (31 December) Gala Dinner per child: EUR 97.50 (from 5 to 12 years old)
- A tax is imposed by the city: EUR 1 per person, per night, up to 7 nights. This tax does not apply to children under 13 years of age.
Optional extras
- Fee for buffet breakfast: EUR 20 for adults and EUR 10.00 for children (approximately)
- Airport shuttle fee: EUR 42.40 per vehicle (one way)
- Self parking fee: EUR 18 per day (in/out privileges)
- Valet parking fee: EUR 18 per day (in/out privileges)
- Early check-in fee: EUR 200
- Late check-out fee: EUR 200
- Rollaway bed fee: EUR 70 per night
- Facilities fee: EUR 50 per person, per day and includes use of:
Hotel Name
- Corinthia Hotel
- Corinthia Hotel Lisbon
- Corinthia Lisbon
- Corinthia Lisbon Hotel
- Hotel Corinthia
- Hotel Corinthia Lisbon
- Hotel Lisbon Corinthia
- Lisbon Corinthia
- Lisbon Corinthia Hotel
- Lisbon Hotel Corinthia
We should mention
This property offers transfers from the airport (surcharges may apply). Guests must contact the property with arrival details before travel, using the contact information on the booking confirmation. Reservations are required for massage services and spa treatments. Reservations can be made by contacting the hotel prior to arrival, using the contact information on the booking confirmation. One child 12 years old or younger stays free when occupying the parent or guardian's room, using existing bedding. Some facilities may have restricted access. Guests can contact the property for details using the contact information on the booking confirmation.


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Looks like the Riders were checking out Johnny Football and got caught tampering. Riders of course denying it at this point.
Hasn't stopped Riderfans from speculating about Steve Young and Manziel as the one two punch they are looking for.
Sounds pretty good to me. Wonder if they will let them room together.
Maybe Todd Marinovich next.


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This week, the Senate Judiciary Committee takes up immigration reform, the day after President Obama's State of the Union Address.
Committee Chairman Patrick Leahy, D-Vt., has voiced support for the principals of immigration reform announced by the White House.
Add to that the immigration reform proposals advanced by a bipartisan group of senators, the so-called "gang of eight," and it appears that the Senate is making the issue a real priority this year.
Sen. Dianne Feinstein, D-Calif., and Sen. Marco Rubio, R-Fla., have spearheaded representation of agriculture's labor needs in the Senate's immigration reform discussions. We look forward to working with them and others in the Senate to keep the reform momentum going.
It's a tougher situation in the House of Representatives, where the Judiciary Committee had an immigration hearing last week. Chairman Bob Goodlatte, R-Va., and other Republicans on the committee fully appreciate the challenges in passing a comprehensive reform measure.
Some political observers think a piecemeal approach to addressing immigration issues, including farm labor, has a better chance of passage.
Also this week in Washington, United's Government Relations Council convenes for strategy meetings and face-to-face dialogue with policymakers from Congress and the Obama administration.
The produce industry's leading executives, representing commodity groups, associations and companies from across the nation, contribute their time and expertise on the council to present a unified voice for our industry.
For immigration reform, that unified voice is even louder this year thanks to a new alliance United has helped to form for advancing solutions for farm labor needs. The Agriculture Workforce Coalition proposes bold new principles for meaningful reform for all of agriculture.
In addition to United, founding members include American Farm Bureau, American Nursery & Landscape Association, Florida Fruit & Vegetable Association, U.S. Apple Association, Western Growers and many more.
The Agriculture Workforce Coalition represents a fresh approach to crafting real solutions for farm employers.
For example, the AWC recommends an uncapped Agricultural Worker Visa Program that would allow for greater flexibility than the current H-2A guest worker program.
This new program proposes that USDA be the administrator, whereas the current guest worker program is administered by the Department of Labor.
The coalition proposes adding this visa program while leaving the current H-2A program intact, thereby allowing employers to continue using H-2A at their option.
Several lawmakers seem receptive to the idea of a worker visa program administered by USDA. The idea also gets support from many farm employers, who believe a USDA-run program could be more responsive to their unique workforce needs.
For the past several weeks, United has been on the Hill getting time with many of the new faces in the 113th Congress, as well as lawmakers from key states and districts who can play pivotal roles on our priority issues.
Especially on the farm labor issue, members of Congress appreciate the chance to learn more and better understand the challenges and costs facing produce industry employers.
In the weeks ahead, if you are asked to make a call, write a note or come to Washington for a meeting with your members of Congress, I hope you'll take the time to make your voice heard about the need for a stable and viable workforce for our industry.
There's a real sense that meaningful immigration reform could happen this year and, when it comes to representing our industry, there's no more powerful voice than yours.
Read more about the Agriculture Workforce Coalition's proposals and the full roster of supporting organizations at www.agworkforcecoalition.org.
Ray Gilmer is vice president of issues management and communication for the Washington, D.C.-based United Fresh Produce Association.
What's your take? Leave a comment and tell us your opinion.


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Getting doors slammed on her face, and the occasional curses did not stop a Vallejo woman from making a difference in her North Vallejo neighborhood.
After knocking on neighbors' doors since 2009, Tina Encarnacion finally received support after her neighborhood, Carriage Oaks, became a haven for burglars.
Encarnacion said that since September break ins and burglaries have spiked.
"We are hit two to three times a week," the mother of three said.
The burglars target empty homes during weekdays, when most residents are at work, Vallejo police said.
Encarnacion said burglars had broken into her garage once four years ago, right after she and her family moved in.
"That was the start," she said of her efforts.
Since then she hasn't stopped, including producing regular newsletters for everyone in the eight-block neighborhood.
A neighbor who has lived in the area for more than a decade said many people were hesitant to speak up and stand up out of fear of becoming a target.
However, people are becoming tired of being prisoners in their own homes and have joined Encarnacion's efforts.
"Without Tina, this can never happen," one neighbor said.
The neighborhood watch has grown from 20 to almost 100 members in the past couple of months, Encarnacion said.
Earlier this month, the group met with Vallejo police Chief Joseph Kreins and Mayor Osby Davis, as well as a Vallejo police captain and lieutenant.
"They have been very supportive and understanding," Encarnacion said.
Since the meeting, extra patrols have been assigned to the neighborhood, depending on the day's call volume, Lt. John Whitney said.
"It's only a temporary fix," Whitney said. "But we are going to support their effort as much as we can."
The burglars are usually juveniles who live in nearby neighborhoods, even though a few have come from Richmond, he said. They also tend to work in groups, he added.
"They are getting more sophisticated," Whitney said. "They have lookouts, use cellphones or two-way radios."
Usually the burglars will knock on a door to check if someone is home. When a resident answers the door, they then would have a bogus excuse for knocking, Whitney said.
However, after they determined that no one was home, they would go around to a side door and kick it in, or break a window to enter.
Even when the home has an alarm system, burglars know they have a window of time before the police arrived.
"They get in, ransack the home, and get out quickly," Whitney said.
Residents should always make sure that their homes look occupied, he added. Rather than answering the door, Whitney recommended making their presence noticed instead, by slamming a door a couple of times, switching a few lights on to show that someone is home, or just talking through the door.
In any case, "don't just sit inside quietly," he said.
Encarnacion said there have been instances when residents have walked into people breaking into their homes. In all of those cases, the suspects have fled.
"I'm afraid someone is going to get hurt... I'm concerned it's going to get worse," Encarnacion said.
Since the issue has become rampant, the neighborhood watch group has decided to become more proactive. The efforts include taking turns patrolling the streets between noon and 8 p.m. by walking or driving around, getting to know neighbors during a monthly meeting, and establishing a phone tree and a website to quickly alert neighbors of suspicious activities.
In February, the neighborhood will hold a "Light up the street" campaign to ask everyone to turn on their porch lights from dusk until dawn.
Whitney also recommended homeowners install motion-sensor lights.
"We haven't seen a slow down in crime since we started," Encarnacion said. "But I think people are more aware. I'm hoping it's going to stop so we all can feel safe again."
The group is also looking into buying surveillance cameras, and hiring an armed guard to patrol the area, she said.
Whitney commended the group's effort to take back their neighborhood.
"They have a lot of good ideas," he said. "I hope they are successful. If we can help them, we will."
Encarnacion said she is going to continue the fight.
"I'm not going to give up, because once I stop I'm going to be the next target," she said.
To donate to neighborhood's efforts, visit www.gofundme.com/1pdz0c.
Contact staff writer Irma Widjojo at (707)553-6835 or firstname.lastname@example.com. Follow her on Twitter @IrmaVTH


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© Viagogo GetMeIn Seatwave Seatwave Seatwave Seatwave Seatwave
Tickets to see Robbie Williams generally sell out very quickly, but thanks to Ticketsmarket.co.uk you can find the last Robbie Williams tickets.
The details of the Robbie Williams concert have been released. See Robbie Williams live in Melbourne. Hurry! There are only a few tickets left or the Robbie Williams concert.
Ticketsmarket.co.uk is an independent marketplace for concert tickets. Compare and find the best price for remaining Robbie Williams tickets available from fans, ticket agents and fan to fan ticket exchanges.


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Q: My sophomore son is struggling in a couple of his classes this semester. His finals are in just a few weeks and we are not sure how to help him. It seems like he is spending the time, but just not getting the results.
A: School is stressful enough, but final exams bring another layer of complexity and anxiety for many high school students. Unfortunately, many students put off dealing with that stress by trying to ignore or push off studying until the very last minute, which does not yield the best results. It is important to sit down with your son and help him prioritize what needs to get done and when. Even though finals are approaching, chances are that he has a slew of projects, exams and quizzes all on his to-do list.
Go through each of his classes and see where he stands numerically. Calculate exactly what he needs to get on each final to get the desired grade. He may find that he has a very solid grade in a few of his classes, and those classes will not require as much focus. This does not mean do not study for those classes; rather, prioritize the classes where the final will make the difference. He may also find that he needs to get an unattainable grade on the final to get a specific grade. While that might not be the best news, it is important to be realistic and set expectations so he does not feel like he is spinning his wheels.
If you are worried about your son failing a class, a call or meeting with the teacher is in order. The teacher will let you know if it is important for your son to be present for that session. Teachers generally do not want their children to fail, especially students who are trying their best.
If your son has missing assignments, ask if he can still turn them in even for partial credit. If he did poorly on a paper, ask if he could do a rewrite for a few extra points and for the learning. Or if there are additional problems the teacher can assign so that your son can master the content. If the teacher is not willing to give additional points or makeups, don't get upset. The teacher has to manage several classes and giving one student leeway can cause a snowball effect. Also, discuss effective studying skills and what your son can do.
Now's the time to map out what needs to get done in each class. On a paper or online calendar, have your son put down what he plans to study in preparation for finals. Note that this studying is in addition to homework, other exams, and projects. He should be pragmatic when creating this calendar; overloading his days means that he is unlikely to complete what he said he would, meaning that he might give up on his scheduling altogether.
Once you have helped him to create a plan of action, talk about distractions that can be eliminated. Children don't need their phones to study; texting has never led to a better grade.
Minimize — but don't eliminate — online time, so that he can be focused. Don't cut out all forms of socializing or relaxing; doing that will only get you a very angry teen.
Instead, teach him how to prioritize and be productive so that he can implement this skill as he gets older and more independent.
Do give him a little more space during this time. If he spends a few minutes less at the dinner table or stays up a little longer, let him. If he's feeling overwhelmed, he needs to find his own ways of coping. For some, that means spending more time hitting the books.
This time will pass and you will get your son back in just a few weeks. And before school starts next semester, sit down with him and reflect on what happened during the first semester so he can be in a better position the next time finals roll around.
Purvi S. Mody is co-owner of Insight Education, an educational consulting firm that helps students throughout the Bay Area to achieve their educational goals. Email her at email@example.com.


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24-hr Intraocular Pressure (IOP) Patterns of Glaucoma Patients After Selective Laser Trabeculoplasty (SLT)
The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified December 2011 by Cheryl Goodness, University of California, San Diego.
Recruitment status was: Recruiting
Recruitment status was: Recruiting
University of California, San Diego
Information provided by (Responsible Party):
Cheryl Goodness, University of California, San Diego
ClinicalTrials.gov Identifier:
First received: December 12, 2011
Last updated: December 19, 2011
Last verified: December 2011
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
The purpose of this study is to determine the relationship between Intraocular Pressure (IOP) fluctuations of glaucoma patients as recorded with an IOP-sensing contact lens (SENSIMED Triggerfish®), during two 24-hour periods after selective laser trabeculoplasty (SLT) for routine treatment of glaucoma.
|Device: SLT (selective laser trabeculoplasty ) SENSIMED Triggerfish
|Study Type:
|Study Design:
|Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Resource links provided by NLM:
Genetics Home Reference related topics: early-onset glaucoma
MedlinePlus related topics: GlaucomaU.S. FDA Resources
Further study details as provided by Cheryl Goodness, University of California, San Diego:
Primary Outcome Measures:
- IOP [ Time Frame: 2 months after SLT ]
|Estimated Enrollment:
|Study Start Date:
|December 2011
|Estimated Primary Completion Date:
|August 2012 (Final data collection date for primary outcome measure)
|Assigned Interventions
|Experimental: SLT
Device: SLT (selective laser trabeculoplasty ) SENSIMED Triggerfish
SLT (single session; 180 to 360 degrees of angle will be treated)
|Ages Eligible for Study:
|18 Years to 90 Years (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
Subjects must correspond to all other inclusion criteria in order to be eligible for the investigation.
- Subject is able to comply with the study procedures
- 18-80 years old
- Subjects diagnosed with glaucoma, based on presence of repeatable visual field loss and/or glaucomatous optic neuropathy based on masked review of optic disc stereophotographs and under ocular hypotensive treatment, or diagnosed with ocular hypertension, with an IOP of > 22 mmHg at the screening visit and under ocular hypotensive treatment.
- Subject has consented to be in the trial
- Visual acuity of 20/200 or better
- Ability to understand the character and individual consequences of the study
- For women of childbearing potential, adequate contraception
Exclusion Criteria:
Subjects presenting with any of the following criteria will not be included in the trial:
- Subjects with contraindications for wearing contact lenses
- Severe dry eye syndrome
- Keratoconus or other corneal abnormality
- Conjunctival or intraocular inflammation
- Eye surgery prior to and throughout the study.
- Full frame metal glasses during SENSIMED Triggerfish® monitoring
- Known hypersensitivity to silicone, plaster or ocular anesthesia (proparacaine)
- Pregnancy and lactation
- Simultaneous participation in other clinical studies
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01495312
Please refer to this study by its ClinicalTrials.gov identifier: NCT01495312
|Contact: Felipe Medeiros, MD
|United States, California
|La Jolla, California, United States, 92037
|Contact: Kaweh Mansouri, MD firstname.lastname@example.com
|La Jolla, California, United States, 92037
|Contact: Felipe Medeiros, MD email@example.com
|La Jolla, California, United States
|Contact: Felipe Medeiros, MD email@example.com
|La Jolla, California, United States
|Contact: Felipe Medeiros firstname.lastname@example.com
Sponsors and Collaborators
University of California, San Diego
More Information
Keywords provided by Cheryl Goodness, University of California, San Diego:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on September 21, 2017
|Responsible Party:
|Cheryl Goodness, Research Associate, University of California, San Diego
|ClinicalTrials.gov Identifier:
|NCT01495312 History of Changes
|Other Study ID Numbers:
|Study First Received:
|December 12, 2011
|Last Updated:
|December 19, 2011
Keywords provided by Cheryl Goodness, University of California, San Diego:
IOP fluctuations
during two 24-hour periods
Additional relevant MeSH terms:
Ocular Hypertension
Eye Diseases
ClinicalTrials.gov processed this record on September 21, 2017


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Mr. John Meeks, Chair
Levy County Commission
Levy County Courthouse
Bronson, FL 32621
Dear Mr. Meeks:
The family of Don "Catfish" Richburg would like to extend our heartfelt gratitude for the love and support from friends, community, and our church family through this difficult time.
We very much appreciate the kind and thoughtful service provided by Knauff's Funeral Home of Chiefland. A special thank you to pastor Gordon Keller and Travis Hudson for presiding over the funeral service and honoring Don's wishes by exalting God and his love for us through Jesus and the gift of salvation.
Luck is a funny thing. Google says luck is success or failure apparently brought on by chance rather than through one's actions. Well as for me I believe in luck. I have always felt lucky to have been born in America, raised by two loving parents who taught me hard work, empathy, dedication, patriotism, integrity, faithfulness, conservation and a million other important values. And luck has been with me most of my life, so you might ask, what is your point?
I don't know about you, but I have had all of the windy days I can stand. Once again, last week was so windy we could only fish a couple of days. I imagine we will want some of this wind in July and August when the dog days take your breath away.
Chickens have been domesticated for thousands of years all over our planet. At one time, just about every farm and many city residences had chickens.
Then starting in the 50's, small towns and cities wanted to have a more progressive image so they banned all livestock and mistakenly lumped chickens in with pigs, cattle, horses and sheep.
The inshore fish picture now seems to be complete, as pretty much all of our expected species have arrived this past week. The warm southern breezes ushered in some very tasty pompano. Though they usually ignore most artificial lures my clients landed a few last week. And in the tug-of-war department they put on a very impressive contest. I also saw some of the first bait pods arrive, I believe they were silversides. I don't think it is coincidence that their arrival happens during the spotted seatrout spawn.
One of the pluses of having a productive garden is that there is always extra produce, enough to share. The reality is that the produce in your gardens will start to go down in quality due to hotter weather, bugs, and spacing of the plants. You all have done a great job of caring for your beds, but in many cases, you will just not be able to eat all of that beautiful produce before it starts to go down in quality.
Copyright © 2017
The Cedar Key Beacon is your source for local news, sports, events, and information in Levy County and Cedar Key Florida, and the surrounding area.


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Part of it is technological advancement, there have been some immensely good discs that have come out in recent years, putters and mids that power up well and long drivers that power down well have reduced the need for a true fairway driver, part of it is that people here are disc nerds who tend to get too excited over new plastic, and also throw significantly longer on average, and can handle faster discs better, the whole game is trying to shift more focus into long drives, part could be that Innova is trying to ruin the disc by producing it in crap blends and "secretly" pushing out +molds, some have ulterior motives like trying to limit themselves to specific molds or companies (like how my bag only has Discmania and MVP, with the JOKERi and FR Premium RESPECTi as utility disc exceptions), and so on and so on.pask2155 wrote:Well I find this fascinating that we have a TB thread and all the fanboys are gone and no one is saying they love this disc... It's the classic, it's a great disc but... Lol.
So I guess if everyone isn't using them anymore then why does everyone refer everyone to them?
Why it gets referenced so often though is that it's one of the yardsticks. Everyone should know how a TeeBird flies just so that they can compare other discs to it. And personally I love it. If our course had more stuff in the 350' range I'd like to use a TeeBird. However as it stands I can either reach every hole with a putter or a mid or I have to go all out, so there really isn't anything for the TB to do. However I always recommend it to newer players, especially in DX, and have heard great feedback from them. It is still a great learner's disc, it can teach you a lot, and like I said, everyone should know how and learn how to throw a TeeBird, or at least an Eagle-X in DX.


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SECAUCUS, N.J. The Children's Place Retail Stores announced first-quarter net income from continuing operations of $28 million, or $1.00 per diluted share for the 13-week period ended May 1, compared with $23.7 million, or 80 cents per share in the first quarter of 2009.
Net sales increased 5% to $422.1 million in the first quarter of 2010, compared with $401.9 in the first quarter of 2009. Comparable-retail sales, which include online sales, declined 0.5% in the first quarter of fiscal 2010 compared with a 1% increase the previous year. During the first quarter of 2010, comparable-store sales declined 1.7% in the United States and 4.6% in Canada, while online sales increased 22%.
"We delivered record financial results and made significant progress on key initiatives in the first quarter of 2010," commented Jane Elfers, president and CEO of The Children's Place. "We strengthened the senior leadership team with the appointment of five talented and experienced executives to head our merchandising, planning, outlet, information technology and human resources operations. In addition, we accelerated our new store openings, sharpened our marketing programs and continued to drive double-digit online growth."
The company updated its guidance for fiscal 2010 and now projects earnings per diluted share from continuing operations will be in the range of $3.05 to $3.15, reflecting its first quarter results, from its initial guidance of $2.90 to $3.10. The company provided initial guidance for the second quarter of 2010, which is forecast to be a loss per share from continuing operations of 38 cents to 33 cents.