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oh she-it yeah i will try and remmeber k lol haha oh remind me to talk to matt when i see him cuz he said i seemed mad at him and we need to talk more so dont let me not do it k lol
6-8 at heights we are lifting wear tennis shoes ...how do you even spell that
??like i know its not tennis shoes but wow idk this is gonna bother me
oh no no no no no !!thats bad stuff..i hope she dont cuz thenwe would be in the dog house again..even though i did not do anything..if your in the doghouse..he throws me in too...oh dear
No, he broke uhp with meh lyk 3 weeks agaoo. I lyk really luved him nd he jus phuckkin left meh with'I need tew focus on my life' OMfg.. Yehh i dnt have a mann. =[
well like i haver to give this note 2 matt...its a long story lol...but like i have to get to 2nd hour early cuz i cant be late again or i will get in trouble..so after 1st hour can you give it to him
its not that interesting it just say he is right5 bout what we talked bout and i love him and i will talk to him after school


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text:
Island Life: One sleep to go
113 Responses
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yeah Che, that's not what they mean by 'a cup of tea and a lie down'.
sigh... where were you emma, old friend.
a raleigh-20 riding gf would have been just my cup of tea.
Probably being introduced to the works of Robert Heinlein by a scruffy-looking bf who used to wear out the soles of his nomads because his cobbled-together bicycle had no brakes.
But that was 1987, so possibly 'in primary school'.
at the age we're talking about i think a cup of tea was about all i could have stretched to.
How I got into soooo much trouble on xmas day. I got a plastic golf set that year, my mate over the road gets the Chopper it was a Reeeed one. Dash across road to beg a ride. I trade some food and I'm off pedalling like fury new owner now left on the pavement. Cue sound effects urrrrrgh ah (car engine noise) change gear stick from 1 to 2 more frenzied urrrrrrgh looking down at gear stick changes…more frenzied urghhhhhhh pedalling fast….holding on with one hand….CRUNCH….I run into the neighbours new car….the chopper is undamaged the car is dented…the laughter can be heard down the street; followed by my desperate scampering feet trying to outrun my Dad who is very red and very very mad………..This image has prevented me from buying a red bike or a red car ever since. I guess childhood is strange like that.
Anyone remember Clark's Grand Prix ?
Lego – so much safer….
hehe, nice story 81st
3140: I had the red with silver Panther. I was always envious of my friend though. His was blue and silver and...waitforit...foot pegs! That, was sweet!
Though mine did have a vinyl thing that domed up over the joint where the handlebars meet the frame. It had a very cool Panther logo on it.
And I had Nomads too. Only got Docs later in college. Funnily enough I bought some dress black shoes a year or so back. They had square toes and a seam ridge around the top, took them home where the GF said "why'd you buy Nomads?"
And why haven't nomads come back into fashion?, along with black puffy nylon bomber jackets?
Strangely, I just got myself a black puffy nylon bomber jacket the other day; a fiver from the sallies. As much to do with my nostalgic fetish for NZ manufacturing as anything else. No heat can escape it. I can't bring myself to wear it in public, due to a sneaking suspicion that I'll look like a dork. I think it's cool, but when it comes to fashion that's no huge endorsement.
In those days I was covetous of my mate's Diamondback; with its totally chrome frame it was a work of art, and had footpegs AND 360 handlebars.
Footpegs? This is clearly some technical innovation that passed me by...
Footpegs let you do "tricks". They were pegs that stuck out from the axel of the rear and (but not always) front wheels.
Gotcha. Sounds dangerous if you're riding two abreast.
(heh heh I said "abreast".)
Are you some sort of commie? Don't you know that there's a clear bright line between "good" smacking and "bad" smacking, and that parents who practice "good" smacking never, ever lose the plot and veer into "bad" smacking? Why, they're practically different species.
Duncan Garner on TV3 just called John Key's light smacking amendment, "good", "smart" and "commonsense".
I remember getting my first bike (the despised Raleigh 20) on my 9th birthday. I was so happy I cried. Wheels = freedom!
I rode that thing until my future husband ran it (and me) into the side of a bridge. I think it went to the tip after that - pity, we owe it a happy retirement.
Children have been pretty silent over s59 (hell, they're pretty silent
on most political issues - and who can blame them? When you're a kid,
there are usually far more important issues, like playing with not-Lego
:) , but it would be nice to see what the people most affected think about it.
I just polled the 8.5 year old (never been smacked) in my household who thinks that a) parents shouldn't smack, because it'll just make kids scared of them and the parents can use it as an excuse for beating b) that there should be a law against it, and c) that light smacking is OK - her definition of light being something that doesn't make the child cry.
Hmmmm. Some contradictions there ...
Happy Birthday to Mary-Margaret!
Ther have been some reports of children saying they prefer smacking, because it's over and done with, and they can just get on with things.
"Don't throw me into the briar patch, Brer Fox", anyone?
In our house, we prefer the sitting chair. Children who have misbehaved are required to sit still on a chair, without talking, in the middle of the family room for varying periods of time (the worst sinner ever got 10 minutes) and reflect on the error of their ways. Any talking or getting out of the chair results in the clock being reset to the original time. Occasionally, the girls get an early release for good behaviour. It also has the handy side effect of making everyone calm down. And, it's over and done with quickly.
BTW, anyone else notice that the Catholic Church has come out today saying that it's okay to hit children in a press release speciously titled, "Children are Precious gifts"? It seems that the rights of the family override the rights of children. That's probably the same sort of family where violence against women used to be tacitly condoned too. Let's reinforce the top down authoritarian approach to being a Christian!
Back to a much more entertaining topic, my brothers and I drove my mother crazy riding round and round and round the house on our bikes. And we scared her half to death riding our skateboards down the drive, and down the steep street towards one of the busier roads in town. Fantastic fun.
What about old fashioned blocks? We had a big box of them, and we spend hours building towns and houses and castles, and setting them all up like dominoes so we could push the first one and listen to the clack-clack-clack as they tumbled down (we called them 'machine-guns'). Not so cool as Raleigh 20s and the like, but wonderful fun. My girls have a big box of them too, and they spend hours and hours building castles, and stables for their herd of "My Little Ponies", and creating designs with the different colours and shapes. I have yet to introduce them to the joys of machines guns - this winter, perhaps.
Email Web
Anne and the others who wished her a happy birthday: MM was chuffed, and thanks you very much for your kind wishes.
I/S: she thinks "there should be a law that tells grownups they can't smack kids."
Also, Lynley came up with the name: it was the Junior Engineering Set.
My younger brothers had one and it is still going strong. My kids all loved it and it lived at Gran's house until she died in 2004.
The brother who loved it the most as a child has it at his place now.
Oh, it's all coming back. What made the set so good was that it included a little battery-powered motor with a spindle that you could rig up to a wheel or a propellor, or a great flying arm. Brilliant.
Lynley and I concurred - if it's not on the market, they really should relaunch it.
In our house, we prefer the sitting chair.
Is there any another kind?
The chair of a standing committee?
the standing chair of a sitting committee.
In our house, we prefer the sitting chair.
Is there any another kind?
That's one of the interesting things about children. You can tell them virtually anything, and they will believe you. Including that unless they are smacked, their souls will be in peril.
Duncan Garner on TV3 just called John Key's light smacking amendment, "good", "smart" and "commonsense".
would that be the Duncan Garner that actually thought George Bush was complimenting him on his dress sense?
Yeah, it's curious and touching and lovely and sometimes quite scary. I snuck in and replaced a missing first tooth with cash the other day... and the 6-year-old burst into tears and cried "who took my tooth!" until she saw the money and little floating flower in the glass of water. Now she really does think it was the tooth fairy, and how do I tell her!
But sometimes I like to kid around with them, and you can just completely make stuff up, and their little faces kind've crunch up with effort- and then they believe it. Really believe it. Like marshmallows are the easter bunny's poos. Or the moon wasn't always there, until this giant got lonely one night- whatever. Sometimes I can't understand how intelligent grown-ups can believe in stuff like god and heaven, and then I think of the little faces in Sunday school....
their little faces kind've crunch up with effort
yes exactly, it's amazing how sometimes with kids you can almost see the effort of the cogs whirring around.
Now she really does think it was the tooth fairy, and how do I tell her!
I finally got fed up with the Easter bunny stories (I'm sure there was no huge Easter bunny hype when I was a child), and told the girls that there was no Easter bunny, and that in our family, we get a few Easter eggs as a treat and we share them on Easter Sunday.
They were okay with that - I think they had always thought there was something dubious about a bunny with eggs.
But on the long drive home after the Easter break, one of my five year olds obviously spent lot of time thinking, and thinking, and thinking. As we were driving out of Wanganui, in a nice demonstration of inference, half worried and half puzzled, she said, "Mum, if the Easter bunny is really just your parents, then maybe Santa Claus isn't true, and it's really just your parents."
Oh dear. There goes the last magical Christmas.
Hey, I teach teenagers (sixth form) who don't know what a continent is, think Africa is a country, wonder how come maps aren't blurry because the earth is spinning so fast that it must make the earth blurry for when they are drawn, wonder what is on the back of the world map (as though there is a whole part of the world we don't know about), have no idea whatsoever of how we have day and night, that the earth orbits the sun, and wonder where the moon goes during the day. These are common things not just the odd student and it's a mid decile school.
I could tell some of them that we are building a bridge to the US, or a flying fox from Mt Cook to Christchurch and they would believe me.
It's all in WHO is telling them the story and HOW STRAIGHT you can keep your face.
And those preachers on TV can keep pretty straight faces.
Oh yeah, and a teaching friend had a year 9 or 10 student the other day who was adament that rabbits DO lay eggs as do dogs. I swear I'm not lying.
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Theft and purse snatching are frequent in public places, including transportation networks and tourist attractions. Ensure that your personal belongings, passports and other travel documents are secure at all times.
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Road conditions are generally good, but are often narrow and lack shoulders.
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See Health to obtain information on this country's vaccination requirements.
- Chikungunya: advice for travellers - September 25, 2017 00:00 EDT
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Pedestrian Projects
The Board of Supervisors has designated $110 million in federal, state and county funding under direction of FCDOT to construct pedestrian improvements in high-priority areas of Fairfax County. These projects include:
- New crosswalks with pedestrian signals
- Upgrading existing crosswalks to include pedestrian signals
- Constructing new walkways and trails
- Upgrading existing walkways and constructing ADA accessible curb ramps
- Pedestrian refuge islands
- Decreasing turn radii
- Curb extensions and bulb-outs
- Bus stop improvements
- Yield to Pedestrian Signs
Fairfax County Major Corridor Pedestrian Initiatives
The Fairfax County Department of Transportation has several pedestrian initiatives underway that aim to increase pedestrian safety, accessibility, and mobility on major corridors including:
- Richmond Highway Public Transportation Initiative: Pedestrian and Bus Stop improvements between Huntington Avenue and Old Mill Road/Mount Vernon Memorial Highway.
- Route 7 Pedestrian Initiative: Pedestrian improvements along Route 7 from the City of Falls Church to the City of Alexandria.
- Route 50 Pedestrian Initiative: Pedestrian Improvements from Jaguar Trail to Arlington County.
Silver Line Pedestrian Access Initiatives
The Fairfax County Department of Transportation also is working to improve pedestrian access around the Silver Line Metro stations by implementing the results of several studies.
- Reston Metrorail Access Group (RMAG): Includes pedestrian improvements around the Wiehle Avenue and Reston Parkway Metrorail stations.
- Tysons Metrorail Station Access Management Study (TMSAMS): Includes pedestrian improvements around the four Silver Line Metro stations in Tysons.
- Dulles Corridor Bicycle and Pedestrian Improvements (DCBPA): Includes additional pedestrian improvements in areas along the Dulles Road corridor.
Pedestrian Projects by District
In addition to these specific pedestrian programs, Fairfax County is working to fill in missing pedestrian links throughout the county.


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Use your iPad to create amazing artwork that you can send directly into Adobe® Photoshop® or Photoshop Extended software (version 12.0.4 or later required).
Paint beautiful works of art on your iPad using a unique five-finger touch user interface that puts the most commonly used tools under your most-used fingertips.
Mix "wet" and "dry" paint to create rich, realistic color blends. Breakthrough technology allows digital paint to "dry" over time.
Paint more freely using the entire iPad screen. Controls for changing color, opacity, and brush size and other settings appear only when you place all five fingers on the screen.
Send your paintings through a wireless network to Photoshop, where they'll be rerendered at a higher resolution and can be saved in any file format you choose.2
Save paintings to your iPad Photos app, and then email them to friends or colleagues as JPEG files.
Store and browse your Adobe Eazel paintings in an in-app gallery.
2 Photoshop must be open, and a network connection between your iPad and computer is required.


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In the midst of all the stuff going on between characters this season, I nearly forgot about a subtle, simmering plot point that has barely been addressed but is still there nonetheless: the rocky relationship between Coach Taylor and Virgil, Jess' dad, the former QB for the Lions in 1983 and the owner of Ray's Barbeque. Early in the season, it was clear that Virgil wanted nothing to do with football, which included Coach Taylor. However, slowly (and subtly.. that's the key-word here), the two came together and in this episode, they work together to bring a community together for a night.
I really liked everything that had to do with the football players and the football team this week. It seems as if week to week, the focus changes from football to stuff that happens outside of football, and this week, the writers show Coach Taylor, Virgil and an ex-convict turned community helper try to get the lights turned back on at a park to play a football game between the school and the community. In the middle of this is some more focus on Vince Howard, who gets a job at Virgil's restaurant and new developments with Luke Cafferty, who seems to have moved past his injury only to end up having bigger problems in the form of Becky's pregnancy. I was worried about how the show would handle this, mostly because the reveal was so random. We know they went on a ride together, but they never implied that they hooked up until tonight. But the show is doing a good job, and in a way, it seems like Riggins may be more of a father figure right now. Unless the show has other plans. Either way, I'm tentatively going along with it.
For all the complaining I did last week about the whole kiss between Tami and Glenn, it ended up having some hilarious consequences. It's obvious that there's nothing that will tear Tami and Coach apart, which means the way they go about dealing with events like this are much different than other melodramatic TV shows and sitcoms. When the Coach discovers about the kiss and laughs uncomfortably, I was laughing too, mostly because Kyle Chandler sells that discomfort so well... also, the way Coach brings up the kiss to Tami ("Glenn told me about a little experience he had at the karaoke bar...") is classic Coach. Everybody should wish they were as cool as this couple.
There's also a new boy on the horizon for Julie and some interesting developments with Landry and Jess, but they were so minor that there's not much to say about it. Basically, Jess hangs out with Landry more than Vince, which makes Vince jealous. I'm sure things will heat up later, but everything else was working so good this week that I'm inclined to forget about that arc.


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PRIORY Vale's Charley Logan has danced almost as long as she has walked, and has now won a place on the Danish Dance Theatre's apprenticeship scheme.
The 21-year-old, who studied at Bradon Forest School before going on to the London Contemporary Dance School, won the coveted place after applying to several post-graduate dance schemes.
Now she needs to raise £2,600 towards the cost of the year-long training scheme, and further funds to pay for her living expenses.
Charley said: "It's such an exciting time. It means I will go out to Copenhagen in August for a month to train with the company.
"Then we come back to London and we get the opportunity to train back here with the theatre.
"From the new year to the spring we will be back in Copenhagen and will go on tour with the company which will be an amazing experience. It's the next step in my career. It's a humongous opportunity.
"I applied to a number of places and had a number of auditions and this was my first choice.
"I got the news the same week as my 21st birthday, so that was amazing. They specialise in performance and since that's what I want to do it really suits me."
Charley first started her dance career at Swindon Dance when she joined the Parents and Tots class at the age of two.
She attended creative and ballet classes and joined the Swindon Dance Company before joining the Youth Dance Academy when she was 13.
Now she hopes to take the next step in her career through her apprenticeship with the Danish Dance Theatre.
The theatre helps to develop students' performance skills by placing them with a host company during the year and giving them the opportunity to perform in professional settings.
Charley said: "I've been dancing since I was very young and I always thought of it just as a hobby.
"It's just something I always felt really passionate about. When I realised that I could actually do it as a career I just knew it was what I wanted to do, and it's just gone from there."
So far, Charley has applied for several grants including the Fund For Excellence and TalentAid to try to raise the money and relied on the support of her family and friends.
She said: "I want to say a big thank you to my friends and family.
"I am so grateful for all the love and support they have given me."
- To offer your support to Charley and help her achieve her dreams, email her at email@example.com


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Walnut Taralli with Roasted Garlic Chèvre
By Greg Higgins
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Taralli are thin rings of bread dough, baked until firm, golden and crisp. They are a great accompaniment to the garlicky goat cheese spread that follows. If you can't make your own dough, see the variation at the end of the recipe.
For the Walnut Taralli:
- 4 teaspoons active dry yeast
- 1 cup warm water
- 1 teaspoon salt
- 1 cup ground California walnuts
- 4 1/2 cups all-purpose flour, plus additional flour for kneading
- 2 tablespoons, more or less, walnut oil
For the Roasted Garlic Chèvre Spread:
- 12 large garlic cloves, peeled (about 1 head of garlic)
- 1/3 cup olive oil
- 12 (1 1/2 cups) ounces plain goat cheese (chèvre) or fromage blanc
- 1/4 cup chopped parsley
- Salt and pepper to taste
For the Walnut Taralli:
- Stir the yeast and warm water together in a large bowl and let stand a few minutes, for the yeast to dissolve. Add the salt, walnuts and 2 cups of the flour. Beat vigorously until well mixed, then add enough of the remaining flour to bring the dough together into a cohesive mass.
- Turn out onto a lightly floured surface and knead for a minute or two. Let the dough rest about 15 minutes. Resume kneading for several minutes, until the dough is smooth, adding just enough additional flour as necessary to keep it from being too sticky to handle. Place in a greased bowl, cover, and let rise until about double in bulk.
- Punch the dough down and divide it into four equal pieces. Cut each piece into eight smaller pieces, about the size of a small walnut. Between your palms (flour them lightly if the dough sticks), roll each piece into a thin rope about 6 inches long. Shape into rings, pinching the ends together firmly. As the rings are formed, place on parchment-lined baking sheets, with at least 1 1/2 inches between each ring. Brush the rings lightly with walnut oil and let rise slightly—just until about half way to double.
- Bake in a preheated 350ºF oven for about 45 minutes, until golden brown and firm to the touch. The baking time is long, so the rings remain crisp when cooled. Remove from the baking pan and cool on racks. Store in an airtight container.
Thaw a 1-pound loaf of frozen bread dough. Place on a floured surface, sprinkle with 1/2 cup ground walnuts, then knead just until the walnuts are incorporated. Place the dough in a greased bowl and let rise until about double in bulk. Punch the dough down, then divide, shape and bake as directed in the recipe. These might need only 35 – 40 minutes of baking, so watch them carefully.
For the Roasted Garlic Chèvre Spread:
- Preheat the oven to 375ºF. In a small baking dish, stir the garlic and olive oil together. Bake 15 – 18 minutes, stirring twice, until the garlic has turned golden brown and softened. Cool to room temperature.
- With the flat side of a fork, crush the garlic into the oil until coarsely mashed. Scrape the garlic and oil into a bowl and add the cheese and parsley. Stir briskly to combine, then season to taste with salt and pepper.
New Review


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Once-daily Antiretroviral Therapy in HIV-1 Infected Patients With CD4+ Cell Counts Below 100 Cells/Mcl (ADVANZ-3)
This study has been completed.
Juan A. Arnaiz
Information provided by (Responsible Party):
Juan A. Arnaiz, Hospital Clinic of Barcelona
ClinicalTrials.gov Identifier:
First received: September 18, 2007
Last updated: February 21, 2013
Last verified: February 2013
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
There are few randomized clinical trials in advanced HIV patients. This is a multicenter, randomized, open clinical trial, comparing three parallel groups, to compare the immunological reconstitution and the virological efficacy and safety of three different combinations of antiretroviral therapy given once a day (QD): tenofovir plus emtricitabine plus either efavirenz, lopinavir-ritonavir or atazanavir-ritonavir during 96 weeks in advanced antiretroviral naïve HIV-1 infected patients with less than 100 CD4+ T-cells/mm3. Primary endpoint is the median increase in CD4+ T-cell count at 48 weeks after starting HAART.
|HIV Infections
|Drug: tenofovir + emtricitabine + efavirenz Drug: tenofovir + emtricitabine + lopinavir-ritonavir Drug: tenofovir + emtricitabine + atazanavir-ritonavir
|Phase 4
|Study Type:
|Study Design:
|Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
|Official Title:
|Once-daily Antiretroviral Therapy in HIV-1 Infected Patients With CD4+ Cell Counts Below 100 Cells/Mcl. A Prospective, Randomized, Multicentre, Open Clinical Study.
Resource links provided by NLM:
MedlinePlus related topics: HIV/AIDS
Drug Information available for: Emtricitabine TenofovirU.S. FDA Resources
Further study details as provided by Juan A. Arnaiz, Hospital Clinic of Barcelona:
Primary Outcome Measures:
- Median increase in CD4+ T-cell count at 48 weeks after starting the HAART combination randomly assigned [ Time Frame: 48 weeks ]
|Study Start Date:
|September 2007
|Study Completion Date:
|December 2012
|Primary Completion Date:
|December 2012 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: 1
tenofovir plus emtricitabine plus efavirenz
Drug: tenofovir + emtricitabine + efavirenz
tenofovir + emtricitabine + efavirenz, approved dose, oral route, QD
Experimental: 2
tenofovir plus emtricitabine plus lopinavir-ritonavir
Drug: tenofovir + emtricitabine + lopinavir-ritonavir
tenofovir + emtricitabine (QD) + lopinavir-ritonavir (BID), oral route, approved dose
Experimental: 3
tenofovir plus emtricitabine plus atazanavir-ritonavir
Drug: tenofovir + emtricitabine + atazanavir-ritonavir
tenofovir + emtricitabine + atazanavir + ritonavir (100 mg), oral route, approved dose, QD
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Chronic HIV-1 infection
- Age 18 or more
- Antiretroviral-naive
- Baseline CD4+ count <100 cels/mcL.
- No mutations of drug resistance at baseline (M184V/I, K65R, resistance to efavirenz or 2 or more PRAMs (L33I/F/V, V82A/F/L/T, I84V, L90M)
- Written informed consent
Exclusion Criteria:
- Hypersensibility to study drugs.
- Pregnancy or breastfeeding
- Active OI requiring admission
- Active lymphoma or malignancy (Kaposi sarcoma included)
- Cl creatinine below 30 ml/min.
- Liver failure
- Treatment with nephrotoxic drugs, immunomodulators, interleukine-2, systemic steroids or investigational products.
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00532168
Please refer to this study by its ClinicalTrials.gov identifier: NCT00532168
|Hospital Clinic
|Barcelona, Catalonia, Spain, 08036
Sponsors and Collaborators
Juan A. Arnaiz
|Study Chair:
|Jose M Miró, MD
|Hospital Clinic of Barcelona
More Information
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Keywords provided by Juan A. Arnaiz, Hospital Clinic of Barcelona:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on September 21, 2017
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Miro JM, Manzardo C, Ferrer E, Loncà M, Guardo AC, Podzamczer D, Domingo P, Curran A, Clotet B, Cruceta A, Lozano F, Pérez I, Plana M, Gatell JM; Advanz-3 Study Group. Immune Reconstitution in Severely Immunosuppressed Antiretroviral-Naive HIV-1-Infected Patients Starting Efavirenz, Lopinavir-Ritonavir, or Atazanavir-Ritonavir Plus Tenofovir/Emtricitabine: Final 48-Week Results (The Advanz-3 Trial). J Acquir Immune Defic Syndr. 2015 Jun 1;69(2):206-15. doi: 10.1097/QAI.0000000000000567.
|Responsible Party:
|Juan A. Arnaiz, MD, PhD, Hospital Clinic of Barcelona
|ClinicalTrials.gov Identifier:
|NCT00532168 History of Changes
|Other Study ID Numbers:
EudraCT: 2006-006268-42
FIS grant: EC07/90642
|Study First Received:
|September 18, 2007
|Last Updated:
|February 21, 2013
Keywords provided by Juan A. Arnaiz, Hospital Clinic of Barcelona:
advanced HIV-infected patients
late presenters
antiretroviral therapy
immune reconstitution
Treatment Naive
Additional relevant MeSH terms:
HIV Infections
Lentivirus Infections
Retroviridae Infections
RNA Virus Infections
Virus Diseases
Sexually Transmitted Diseases, Viral
Sexually Transmitted Diseases
Immunologic Deficiency Syndromes
Immune System Diseases
Atazanavir Sulfate
HIV Protease Inhibitors
Protease Inhibitors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Anti-HIV Agents
Anti-Retroviral Agents
Antiviral Agents
Anti-Infective Agents
Cytochrome P-450 CYP3A Inhibitors
Cytochrome P-450 Enzyme Inhibitors
Reverse Transcriptase Inhibitors
Nucleic Acid Synthesis Inhibitors
Cytochrome P-450 CYP2C9 Inhibitors
Cytochrome P-450 CYP2C19 Inhibitors
Cytochrome P-450 CYP2B6 Inducers
ClinicalTrials.gov processed this record on September 21, 2017


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mickas wrote:You know Danny? How's he doing in the twin cities? I haven't seen him in a month or two.
I did however see his cart at one point or another, I didn't know his and jay's were one in the same, it's a sweet rig.
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Skip to Content
Five finalists for the position of director of the University Memorial Center at the University of Colorado at Boulder will begin campus visits April 23.
Members of the campus community are encouraged to attend the candidates open forums and offer feedback to the search committee co-chaired by Gary Chadwick, director of the Recreation Center, and Adam Fingersh, representative-at-large of the University of Colorado Student Union.
The finalists, their current positions and dates of campus visits are:
J.C. Ancell, UMC associate director from 1982 until 1996, when he was appointed interim director, April 23.
Jodie Cottrell, former acting associate dean of student services at New Jersey Institute of Technology in Newark, April 25.
Guy Conway, director of Milo Bail Student Center at the University of Nebraska, Omaha, April 28.
Carlos Garcia, director of the student union and housing at the University of Texas, El Paso, April 30.
Paul M. Simon, former executive director of the student union at Queens College/City University of New York, Flushing, May 2.
The UMC directors position has been held on an interim basis by Ancell since the departure last September of Jim Schafer.
For scheduling information call Student Affairs at 492-3508.


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Viewpoint: It's All About Power – Strategies And Goals
EP Editorial Staff | June 2, 2006
The business challenges in manufacturing these days are very different from the past. Today, facilities are competing with countless others around the globe. Competition, though, also opens up a number of growth opportunities. But, to fully participate in those opportunities, companies will need to increase productivity, reduce costs and speed up cycle time-while maintaining high levels of quality.
This need to improve efficiencies and maximize availability also requires the ensuring of increased safety and security levels.Moreover, at the same time the market is seeking the flexibility to act on new and changing demands, it often is having to deal with new governmental rules and regulations.
When it comes to coping with these many challenges, the specific strategies you choose to follow are crucial to your success. Some of these specific strategies (and the tactics to implement them) involve the individuals in charge of maintenance at a facility. One of the most important decisions maintenance faces today concerns production shutdowns.
The days of shutting down production lines to perform regular maintenance are over. For whatever reasons, be they downsizing, cost concerns or others, in many facilities the typical approach has become one of repairing equipment after it breaks down. Such an approach, however, does not allow a facility to maximize its capacity.
Maintenance departments must truly get their arms around effective predictive maintenance. This requires continuously collecting and analyzing historical data, quality data, safety data, etc. and the introduction of state-of-the-art predictive maintenance tools.With better information and tools, it is far easier to find opportunities for improvement and reduce Mean Time To Repair. Another important strategy involves more automation in the production process, and the getting away from disparate networks. Seamless corporate networks pave the way to increased efficiency– and enable maintenance to implement the best predictive maintenance strategies.
But, let's imagine what would happen if, after choosing and implementing these and other strategies to enhance your uptime and productivity, that your facility suddenly found itself without power. . .
As more and more plants move to automated control of their processes, they are introducing more digital equipment in their facilities. This has dramatically increased the need for a stable, secure and high-quality power supply that ensures production and business continuity. Thus, the strategies a company adopts in regard to power availability are more critical than ever before. As a global leader in power availability solutions, our company clearly recognizes that downtime is not an option. Therefore, we are always challenging "the status quo" and striving for new ways to meet your needs.
To do this,we constantly are looking at the challenges facing the market (both existing and emerging challenges).We also are listening carefully to our customers' comments and concerns, including how they view their future business challenges. The answer (and, with it, the future) clearly calls for facilities to be able to obtain uninterruptible power system solutions, 24/7.
In a world that demands zero downtime, we view our primary goal as one of providing you with these types of cost-effective system solutions—and real peace of mind. That, in turn,will allow you and your facility to fully concentrate on the type of business strategies that lead to your goals: continued growth and success. MT


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Roenicke: No plans to send Axford to Minors
MILWAUKEE -- The fans made their voices heard again Sunday, but Brewers manager Ron Roenicke was adamant: There has been no talk of sending reliever John Axford to the Minors to iron things out.
After an eight-game stretch in which it appeared he had moved past his early-season struggles, Axford heard boos as he left the mound Sunday for the second straight outing. He'd just surrendered a run on two hits and two walks while recording one out in a 10-1 loss to the Cardinals.
The appearance boosted his ERA to 9.95 and his walks plus hits per inning pitched to 2.76 over 12 2/3 innings.
"Today was the first time that I felt off since that outing in Chicago," Axford said, referring to an April 9 loss to the Cubs. "Every time after that, I felt good. Mechanically, the ball felt good coming out. Today was one of those days where I just didn't physically feel like myself."
Axford does have Minor League options remaining, but Roenicke indicated that was not a consideration at the moment.
"No, it's not [under discussion]," Roenicke said. "We feel he can get it back together. We saw him do it last year, and still feel that he can do it. … It's the same thing that he was in [last season], whether it's confidence, whether it's mechanical. If it's mechanical, Rick [Kranitz, the pitching coach] and Lee [Tunnell, the bullpen coach] will figure it out.
"I don't think it is mechanical, as far as not putting him in a spot where he can make good pitches. But I don't know that it's all mental, either. I think Ax, he goes through things like this. Even when he was really good two years ago, he still gets in full counts a lot. He's not a guy that just commands the ball great and is a strike-thrower all the time. But working with the delivery and upstairs with the confidence, he's got to get both of them back."
Catcher Jonathan Lucroy also weighed in.
"He just has to get comfortable again," Lucroy said. "He's way too good to be doing this for long. He's throwing 96, 97 mph, and if he can just get his off-speed over early for strikes, there's not a lot of people who are going to have a chance. In 2011 when he was really, really good, that's what we did -- we got ahead early and put people away."
Axford's popularity soared at the time, because he was the key cog of a shutdown bullpen that helped the Brewers reach the 2011 National League Championship Series. But he struggled in the middle of 2012 and briefly lost the closer's job, then lost the job again after three outings this year.
He was asked whether the boos are contributing to his trouble.
"No, because when I'm on the mound I'm locked into what I'm intending to do on the next pitch," Axford said. "I never hear anything when I'm out there."
What about when he is coming off the mound?
"Coming off, you hear more things," Axford said. "If I could erase those first four outings where things weren't there mechanically, when the velocity wasn't there -- if I could get rid of those games, then maybe things are a little bit different. Maybe I feel different. Maybe the crowd feels different, too. But it's tough to get rid of those outings, tough to forget about them.
"So, I understand where [fans] are at. It is what it is. It's difficult."
Adam McCalvy is a reporter for MLB.com. Read his blog, Brew Beat, and follow him on Twitter at @AdamMcCalvy. This story was not subject to the approval of Major League Baseball or its clubs.


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Da-Lite CINEMA CONTOURCHCP 130D69X110 (34652V)Item#: 40173747 | Model#: 34652V
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Rick Tyler, spokesman for former House Speaker Newt Gingrich and co-counder of ReAL — Renewing American Leadership, said he felt a little intimidated to be speaking to a group whose last speaker was U.S. Senate Candidate Marco Rubio.
If you currently subscribe or have subscribed in the past to the Chiefland Citizen, then simply find your account number on your mailing label and enter it below.
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It's the place to go if you're thinking about investing in a recreational vehicle. Hours: 11 a.m.-9 p.m. today and Saturday, and 11 a.m.-5 p.m. Sunday at Memorial Coliseum, 4000 Parnell Ave. Admission: $6 adults, $4 ages 60 and older; $2 ages 5-12. A family day pass (two adults and up to three kids) is $14. Sunday is Family Day — ages 12 and younger get in free. If you're going today, go to www.rvshows.org/Portals/322/FtWayne/2013_FW_show_discount.jpg to get $1 off today's admission.Brides-to-be are invited to the Monogram Shoppe and more … for a special event, Super Bride Sunday, noon-4 p.m. Sunday. Yes, you'll still get home in time for the big game.
Store owner Sara Keltsch says the event gives women something to do while the guys are watching the pre-game show.
The first 50 brides-to-be will get a free tote bag. Door prizes will be awarded, and the store is offering 10 percent off bridesmaids' and groomsmen's gifts, as well as jeweled cake toppers. There will be cake sampling, music and more. The Monogram Shoppe is in Covington Plaza at 6410 W. Jefferson Blvd.Merle Norman Cosmetics in Covington Plaza is hosting a Most Kissable Lips contest today through Feb. 9. Women can come into the store at 6386 W. Jefferson Blvd. and kiss a paper that will then be placed in the store's front window. At 4:30 p.m. Feb. 9, Judge John Surbeck will judge the "kisses." Information: 432-9315.Don't forget the Fort Wayne Farmers Market 9 a.m.-noon Saturday at Parkview Field in the indoor Lincoln Financial Event Center. More than 40 vendors and artisans will sell food, farm products, natural products and handcrafted items. The Three Rivers Orchid Society will present a program. Information: www.ftwaynesfarmersmarket.com.Just a year ago, J.C. Penney made major changes to its pricing, lowering prices on everything 40 percent and dispensing with most of its sales.
Apparently the strategy was a flop. According to an Associated Press story, J.C. Penney CEO Ron Johnson said the department store chain this week will begin adding back some of the sales it curtailed last year.
Here's more from the AP story: "Penney also plans to add price tags or signs for more than half of its merchandise to show customers how much they're saving by shopping at the chain — a strategy used by a few other retailers. For store-branded items such as Arizona, Penney will show comparison prices from competitors.
"The reversal comes on the eve of the one-year anniversary of its original vow to almost completely get rid of the sales that Americans covet but that cut into a store's profits. The idea was to offer everyday low prices that customers could count on rather than the nearly 600 fleeting discounts, coupons and sales it once offered."
The story goes on to say, "Penney next month is expected to report its fourth consecutive quarter of big sales drops and net losses. After losing more than half of its value, Penney's stock is trading at about $19. And the company's credit ratings are in junk status."
I guess it shows just how much we shoppers like our sales.
Know of a store opening, closing or remodeling? Find a good deal? Call Cindy Larson at 461-8284, fax 461-8817, email firstname.lastname@example.com or write to: In the Bag, C/O The News-Sentinel, PO Box 102, Fort Wayne, IN 46801. To read other columns, go to www.news-sentinel.com/section/LARSON.


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Taylor has small labrum tear, won't need surgery
TEMPE, Ariz. -- Lefty reliever Andrew Taylor, who made three appearances as a September callup with the Angels last year, has a small tear in his labrum, a MRI on Monday revealed.
The good news for the Angels is it won't require surgery; the bad news is he'll be shut down and limited to rehab work for an indefinite amount of time.
"It's different with everybody, so it could be a week, two weeks, two months; it could be anytime," Taylor said. "It's just when my arm is not painful at all."
Taylor, 26 and in Major League camp, was taken by the Angels in the 34th round of the 2008 First-Year Player Draft and pitched primarily in Double-A and Triple-A last season, compiling a 4.27 ERA in 59 innings. He's still experiencing pain when throwing a baseball.
"I want to be on the field," Taylor said, "so I have to make sure everything's good. I don't want to rush it back."
Alden Gonzalez is a reporter for MLB.com. Read his blog, Gonzo and "The Show", and follow him on Twitter @Alden_Gonzalez. This story was not subject to the approval of Major League Baseball or its clubs.


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High school students from the statewide program Youth in Natural Resources will participate in a variety of seminars and hands-on activities at the CU-Boulder Integrated Teaching and Learning Laboratory on July 16 from 1:45 p.m. to 2:45 p.m.
Hands-on lab experiments will expose students from various ethnic and cultural backgrounds to opportunities in natural resources, the importance of environmental issues and the benefits of higher education. Students will conduct experiments with ITLLs interactive exhibits on topics like fluid dynamics, chaos theory and weather.
ITLL, located in the College of Engineering and Applied Science, is an interactive laboratory designed to engage undergraduate engineering students in real world research. The facility also is being used by Colorado school children and teachers to generate interest in engineering and science.
YNR is an intensive conservation corps and environmental education program. The students, who come from diverse backgrounds, are paid minimum wage during the summer to perform environmental work throughout Colorado and participate in educational activities introducing them to natural resource issues and job opportunities.
For more information contact Amy Taylor, CU-Boulder Public Relations, at 492-8384 or Pat Martinez, YNR Program Coordinator, at 866-2540. Exhibits and experiments are suggested as possible feature photographs.


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A few wet years can cleanse the memories of last decade, when Canberra was struggling through its worst drought on record. Today, the city's dam levels are up to almost 95 per cent of their capacity and most of our parks, gardens and sportsgrounds are a fertile green. Yet this is the result of a very rare event: two consecutive La Nina cycles over 2010-11 and 2011-12, which dumped a generous volume of rain on the region. Climate scientists say these cycles will occur less often, and tend to be weaker, in the years and decades ahead.
The Bureau of Meteorology's Annual Australian Climate Statement, released last week, jolts us back to the realities of living on a warming planet. The extreme heatwave now affecting most of eastern Australia is not a one-off; forecasters worldwide already fear that 2013 will be the globe's hottest year on record. This not only means more of the intense heat, bushfires and severe storms from which Australians are now sheltering, but a return to the critical question of how we manage our water reserves.
Five-a-half-years ago, Canberra faced a crisis. Water utility Actew reported grimly: ''By June 2007, water levels in our dams had dropped from 50 per cent a year earlier to 30.8 per cent, an all-time low.'' Plans were under way to enlarge Cotter Dam twentyfold and to build a high-tech purification plant that would add treated wastewater (including sewage) to the city's drinking water supplies.
Canberrans' reaction to this latter proposal was surprisingly supportive given the anger with which Toowoomba residents had greeted a similar proposal. Nonetheless, some high-profile opponents emerged, not least Canberra Hospital's head of microbiology and infectious diseases, Professor Peter Collignon. The ACT's then chief minister, Jon Stanhope, eventually dropped the proposal to recycle wastewater, and instead proceeded solely with the Cotter enlargement, which increased our dams' total capacity by 35 per cent.
Today, a near-overflowing Cotter Dam may appear to vindicate Mr Stanhope's decision. The ACT government also has the benefits of the newly built pipeline from the Murrumbidgee River to the Googong Dam and a deal to use it, if needed, to take water from Tantangera Dam in NSW.
Yet the ever-worsening prognoses for our climate suggest we should drink in the sight of a full Cotter now; it may be a very rare luxury. Nor should we assume that, when we need water from Tantangera, other communities in NSW won't make equally strong cases to use it. On top of that, the ACT's population is expected to soar from 370,000 now to about 500,000 in just 30 years. Unless we learn to use much less potable water per household, our demand will soon exceed even the newly expanded supplies of Actew.
It's likely that, sometime in the not-too-distant future, Canberra will again debate whether we should add purified wastewater to our drinking supplies. Perhaps we'll then reflect back on Mr Stanhope's cautious decision, and ask whether it was as wise as La Nina, and her fleeting charity, led us to believe.


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First collection revealed...
To insure your action figure collection, get in touch with Collectibles Insurance, the official insurance company of the Figures.com network. Say "Figures.com" to get 5% off your first term premiums.
To buy action figures, take a look at BigBadToyStore.com, RedfordFilms.com, Toynk.com, PastGenerationToys.com, BriansToys.com, ToyWiz.com, and MonkeyDepot.com.
In January, McFarlane Toys announced that it was joining forces with Xbox LIVE and 343 Industries to bring Halo fans an all-new series of unique collectibles: Halo Avatars (read our story HERE). Halo Avatars are based on the stylized representations of the Halo characters that are available on the Xbox 360 console itself.
XBOX LIVE AVATARS: HALO SERIES 1 consists of eight random figures:
- Master Chief
- Carter
- Flaming ODST Helmet and ODST T-Shirt
- Green Operator Helmet and Reach T-Shirt
- Elite Costume
- Metallic Gold Master Chief
- Warthog
From Halo-themed t-shirts, to Spartan helmets, to full suits of character armor, gamers can make their avatars look like true Halo fans, or even characters from the Halo universe. To represent the customization options available to online avatars, McFarlane Toys' avatar figures feature interchangeable heads, torsos, and legs. Collectors can mix and match pieces to create their own custom avatar figure, much like they can with their online avatar.
Each 2 1/2" tall avatar figure is randomly packaged in a small, Halo-themed plastic cylinder. The top and bottom of each cylinder can be removed, and each piece can be used as a display base. The tubes can even be connected, stacking to form a multi-level display.
Pick up your avatars this August at Gamestop, Target, Toys"R"Us, Wal-Mart – Canada, Blockbuster - Mexico, Toys R Us - Canada, Fred Meyer, Kroger, HEB, F.Y.E, local comic book stores, and other retailers nationwide.


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Influence of Thyroid Hormones on the Woundhealing Process
The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified June 2009 by Hannover Medical School.
Recruitment status was: Recruiting
Recruitment status was: Recruiting
Hannover Medical School
Genzyme, a Sanofi Company
Information provided by:
Hannover Medical School
ClinicalTrials.gov Identifier:
First received: June 26, 2009
Last updated: NA
Last verified: June 2009
History: No changes posted
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Main goal of this clinical investigation is to investigate different cytokines in wound fluids of euthyroid vs. hypothyroid patients. As a primary endpoint we want to evaluate if different cytokine levels in euthyroid vs. hypothyroid patients exist and to what extent these cytokines differ. Our targeted cytokines are: IL6, IL10, TNFa and MCP-1. From the literature these 4 factors seem to be the most reasonable to measure and to focus on. Additionally we focus on these 4 factors for financial reasons, technically there wouldn't be a problem to measure more, which is correlated with higher costs. Besides, more than 6 factors would mean larger amounts of sample fluids needed, which would cause technical problems. These factors don`t have to change in the same direction. Secondarily, we believe that differences in cytokine profiles of hypothyroidism vs. euthyroidism will correlate to differences in duration and clinical characteristics of the wound healing process.
|Thyroid Neoplasms Thyroid Carcinoma
|Procedure: blood sampling
|Study Type:
|Study Design:
|Allocation: Randomized
Masking: None (Open Label)
Primary Purpose: Basic Science
|Official Title:
|Clinical Investigations on Cytokin-Gradients in Hypo/Euthyroid Patients. Evaluation of Expression of Different Pro-and Anti-Inflammatory Cyto-/Chemokines in Skin Wounds After Surgery of Benign Goitres (Struma Multinodosa) or Malignant Diseases of Thyroid Gland (Papillary Thyroid Carcinoma) in Correlation to the Status of Wound Healing of the Neck Wound
Resource links provided by NLM:
MedlinePlus related topics: Thyroid Cancer Thyroid Diseases
Drug Information available for: ThyroidU.S. FDA Resources
Further study details as provided by Hannover Medical School:
Primary Outcome Measures:
- Evidence for different cytokine levels in euthyroid vs hypothyroid condition confirmed by bood serum samples [ Time Frame: 21 days after surgery ]
Secondary Outcome Measures:
- Differences in duration and clinical characteristics of the wound healing process verified by a modified ASEPSIS score. [ Time Frame: 21 days after surgery ]
|Estimated Enrollment:
|Study Start Date:
|June 2009
|Estimated Study Completion Date:
|April 2010
|Estimated Primary Completion Date:
|December 2009 (Final data collection date for primary outcome measure)
|Assigned Interventions
Active Comparator: benign
patients after surgery because of a benign disease
|Procedure: blood sampling Procedure: blood sampling
Active Comparator: DTC
Patients after thyroidectomy because of papillary carcinoma of the thyroid gland
|Procedure: blood sampling
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Near total or total thyroidectomy because of struma multinodsa (nodular goiter) with or without substitution of thyroid hormone after operation
- Total thyroidectomy because of papillary carcinoma of thyroid gland (T1/T2 carcinoma, N1, M0) with planned radio-ablative therapy (RAT) without or with rhTSH
Exclusion Criteria:
- Pat< 18 years
- Immune disease of thyroid gland (Graves disease)
- Severe immunodeficiency
- Immunosuppressive medication because of solid Organ transplantation
- Hepatitis A/B/C or HIV
- All exclusion criteria for any surgical procedure
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00929318
Please refer to this study by its ClinicalTrials.gov identifier: NCT00929318
|Contact: Stephan S Kaaden, Dr
|0049-511-532 6131
|Contact: Georg FW Scheumann, Prof
|0049-511-532 2032
|Medizinische Hoochschule Hannover, Allgemein-, Viszeral-und Transplantationscirurgie OE 6220
|Hannover, Germany, 30625
|Contact: Stephan Kaaden, Dr
|Sub-Investigator: Stephan Kaaden, Dr
Sponsors and Collaborators
Hannover Medical School
Genzyme, a Sanofi Company
More Information
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on September 21, 2017
|Responsible Party:
|Prof. Dr Georg FW Scheumann, Medizinische Hochschule Hannover
|ClinicalTrials.gov Identifier:
|NCT00929318 History of Changes
|Other Study ID Numbers:
|Study First Received:
|June 26, 2009
|Last Updated:
|June 26, 2009
Additional relevant MeSH terms:
Thyroid Diseases
Thyroid Neoplasms
Neoplasms, Glandular and Epithelial
Neoplasms by Histologic Type
Endocrine System Diseases
Endocrine Gland Neoplasms
Neoplasms by Site
Head and Neck Neoplasms
ClinicalTrials.gov processed this record on September 21, 2017


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text:
Retired pitcher Carpenter to join front office
ST. LOUIS -- General manager John Mozeliak confirmed on Saturday that Chris Carpenter will join the front office this season in a to-be-determined role. Carpenter, who did not speak with the media after his Winter Warm-Up appearance, had expressed an interest in remaining with the organization once his playing career ended.
He officially retired in November.
Carpenter's new role, which has not yet been titled, will not be a uniformed one. Rather, he'll get an introduction to various front-office and scouting duties by working with Mozeliak and other members of the baseball operations staff.
"We're going to try to come up with the curriculum for him that allows him to get exposure to the different elements of our front office. I welcome that," Mozeliak said. "I've known him a long time, and I think his insights could be valuable. I think the key is, how do we harness it? How do we come up with something that isn't too overwhelming in the first month or year, but also keeps him interested?"
Carpenter will spend some time in Jupiter, Fla., during Spring Training to participate in a training program the Cardinals host for their young scouts. The transition into a front-office job is made easier by the fact that Carpenter has made St. Louis his home.
Once Mozeliak finalizes the job description, the organization will officially announce the staff addition.
"Obviously, i's need to be dotted and t's need to be crossed," Mozeliak said, "but he's excited to do something and we want him to do something."
Jenifer Langosch is a reporter for MLB.com. Read her blog, By Gosh, It's Langosch, and follow her on Twitter @LangoschMLB. This story was not subject to the approval of Major League Baseball or its clubs.


text:
a little golden
There's something about the tiniest bit of gold or brass that instantly makes a space more interesting. Especially with lots of matte white and grey surfaces, small amounts gold add a lived-in and sophisticated quality.
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From Australia's SBS Television: Greeks with Australian citizenship are returning here in the hope of finding jobs and a better life, away from the instability crippling Greece's economy.
Which is why so many Greeks left home and family behind for the American Dream in the early 20th Century:
Greeks began to settle in America at the end of the 19th century and the influx of migrants continued up until the 1920s. Around 400,000 Greeks migrated to America at that time, primarily from the Peloponnese and the rest of southern Greece. Three quarters of the immigrants settled permanently in America, in large urban centers such as Chicago, New York and tens of smaller cities scattered across the country reaching as far as California. They engaged in various forms of employment such as street vendors and shop owners. Many were restaurateurs while others worked in more manual jobs such as cotton mills, coalmines, or on the railways.
Australia's ranking on the 2013 Index of Economic Freedom: 3
Greece's ranking on the 2013 Index of Economic Freedom: 117
The United States' ranking on the 2013 Index of Economic Freedom: 10
There are at least six "self made" Greek-American billionaires on the Forbes 400 list.
Economics in Christian Perspective: Theory, Policy and Life Choices
There is considerable debate in the public square these days about a number of issues that have significant economic components. Globalization, environmental protection, and aiding the poor are just a few. Decisions we make in our personal lives are influenced by our assumptions about economic realities as well. So how might mainstream economics connect with Christian values and principles?


text:
Tuberculois is a bacterial infection that attacks the lungs. The disease is contagious, can be fatal and has slowly outsmarted some of the drugs used to treat it.
That's where Janssen Therapeutics of Titusville, N.J. comes in.
The firm — one of the pharmaceutical companies of Johnson & Johnson — has just won FDA accelerated approval for a new tuberculosis drug. Janssen announced Monday that SIRTURO will be commercially available in the U.S. by the second quarter of 2013.
The new drug will address a small problem domestically, admits Janssen spokesperson Pamela Van Houten. But it could be a key weapon in the fight against a growing menace abroad.
"This compound was discovered by Janssen scientists in our laboratories, and we really felt that it was just too important to not develop," Van Houten said.
SIRTURO is the first ever medicine designed specifically for multi-drug resistant TB.
In 2011 there were only 98 reported cases in the U.S. "However, globally there were over 600,000 cases," said Van Houten. "This is a disease that is on the rise and is very, very important to treat when it occurs."
Multi-drug resistant TB is most prevalent in parts of Central Asia, Eastern Europe and Africa.
Janssen will continue testing the drug while it seeks approval for SIRTURO in those markets. Van Houten says U.S. approval is key, however, because global regulators often look to the FDA.


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India's limited overs mainstay Suresh Raina got himself embroiled in a controversy last night, all from the confines of his own home.
It all started when a tweet emerged from Raina's verified Twitter account that said this
Twitter has already contributed to the downfall of several big names from the cricket world (Lalit Modi and Kevin Pietersen are just two examples) and this time too, the micro-blogging site was at the centre of what could be mildly described as an inappropriate reaction from a national cricketer.
Twitter users were quick to latch on to the post and the immediate feedback might have prompted Raina to delete the tweet. The damage however had been done and screenshots of the post swiftly made the rounds to those who had missed it.
Suresh Raina did attempt some damage control this morning, attributing the provocative tweet to his nephew who apparently had got hold of his smartphone -
@ImRaina : Smart phones r dangerous. Discovered it last night after my nephew posted random tweets. I'm a sportsman and would never disrespect.
@ImRaina : Though I already deleted it, I felt its better to clarify. To all those who r upset, I'm sorry. I'm not one to show disrespect.
As expected, the move backfired, with people questioning the truth behind his excuse and also pointing out that there was just a difference of two minutes between that tweet and the next one about him looking forward to joining the Chennai Super Kings for the Champions League.
Raina's response spawned a deluge of tweets from Twitter users poking fun at the middle-order batsman and his 'nephew'. It even prompted a spoof account for the so-called nephew.
Here are some of the more hilarious responses on Twitter:
Raina's Nephew @Raina_Nephew: Since it is time for revelations... I was responsible for the JFK bullet as well
Ramesh Srivats @rameshsrivats: Suresh Raina's favorite mythological character must be Kamsa. He also had big problems with his nephew.
IbneBattuta @Ibnebattuta: Meanwhile inspired by @ImRaina Dhoni is on the look out for a Nephew excuse for the T20 eviction.
Fake IPL Player @_fakeiplplayer: If Suresh Raina's thumb is his nephew, what is Virat Kohli's middle finger to him?
Raheel Khursheed @Raheelk: 'My nephew slept with the maid.' Shiny Ahuja


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text:
Right now might be the right time to look into a potential J.O. deal. Hear me out though.
I don't know if he's just not healthy, or if he's not healthy/not happy with his role on the team. He looks like he plays his role right sometimes, but he doesn't look like he is a big believer in the role he plays. We need believers. You can't turn a 29 year old 20-10 kind of guy that's never averaged more than 2.6 apg, into a guy that plays a Vlade Divac like role. It's just not working.
He's not necessarily bogging down the offense all the time, but sometimes is too much right now. I know we don't expect a championship right now, but the expectations set by our own coach is the playoffs. Diogu has shown a lot in his time this season and has shown he's taken his game to another level. Maybe Diogu can be put in J.O.'s role (if we can ever get him healthy).
The reason why I say now might be the time is because making a deal sooner than later gives the team a chance to learn each other in hopes of making a strong run after the All-Star break. Instead of doing what we did last season and making the deal mid-season which might have killed our playoff run.
I'm going to predict that Larry Bird is probably already looking at what needs to happen to improve this team. We've improved this teams chemistry, but what we still don't have is a whole lot of mental toughness. And we lack leadership. We need a player that can take over the game in a major way, but not necessarily an All-Star. I could be describing Ben Gordon (?)
Some might remember the thread I made like this about Al Harrington last season a number of days before the big trade: http://www.pacersdigest.com/apache2-...ad.php?t=27743
I'm not bothering with the trade checker this time because I think this is a more difficult trade than the Al Harrington deal. But I think it's time. Don't wait for a potential opt-out. Don't wait for Jermaine to completely shut down (because it's almost looking like that might happen). Address our needs now. Unlike in the off-season, we have some tradeable players that can be packaged with Jermaine to actually help us. I haven't been for trading Jermaine in the past, but right now I just think it's do or die... And I do mean right now.
Be easy on me....


text:
Prize Recipient
Tamela Maciel
There has never been a time when I haven't been passionately intrigued by how the universe works. It always amazed me that the same laws that governed the motion of a leaf as it fell to the ground might also apply to the motions of stars and galaxies millions of light years away. I have long been anxious to study physics for precisely this reason: so that I might better be able to make those connections between our familiar world and the extremely remote world of space.
I grew up in Grants Pass, Oregon and graduated valedictorian a year early from Grants Pass High School. Currently, I am a rising sophomore at the University of Oregon where I study physics, astronomy, and chemistry. I volunteer at a local planetarium and give hour-long presentations to the public. I am also co-president of the UO Society of Physics Students and help to plan talks, discussions, lab tours, and field trips for the group. Finally, I am employed in the undergraduate physics labs at UO where I maintain the labs and equipment for student use. Outside of school, I love to sail, hike, run, bike, practice my violin, and of course, star gaze! This summer, I was part of the 2007 Motivating Undergraduates in Science and Technology (MUST) program where I spent ten weeks at the Goddard Space Flight Center researching active galactic nuclei. In a few years, I plan to attend graduate school and earn my PhD in astrophysics.


text:
Moderator: Mahavihara moderator
Dhammanando wrote:It is held to be an indispensible doctrine.
Kammic efficacy and rebirth are part of mundane right view. To reject or doubt rebirth is to suppose that there are some causes that don't yield effects – specifically, that there can be ignorance and craving that will not issue in further becoming. Those of such a view have not understood the conditionality of dhammas even at the intellectual/pariyatti level. To not understand this is to not understand the four noble truths, the three characteristics, or anything else that is of decisive importance in the development of paññā.
Peter wrote:... it is important to adopt the view that it actually happens.
Jechbi wrote:In this respect, I tend to agree with the approach Ben suggests, namely, to set aside for the moment those views that one cannot bring oneself to accept, and to continue on with the rest of practice.
But I wonder if this approach is in line with classical Theravada thought, because an argument seems to be made that the correct method for adopting right view regarding rebirth is to simply accept it, regardless of whether one believes it. To me that seems like putting the cart before the horse, although I stand to be corrected.
"I inform you, great king, I announce to you, great king: aging and death are rolling in on you. When aging and death are rolling in on you, great king, what should be done?"
"As aging and death are rolling in on me, lord, what else should be done but Dhamma-conduct, right conduct, skillful deeds, meritorious deeds?
mikenz66 wrote:... attempting to develop insight without establishing Right View will cause problems (falling into nihilism, as I recall).
Jechbi wrote:mikenz66 wrote:... attempting to develop insight without establishing Right View will cause problems (falling into nihilism, as I recall).
If right view and right thought are wholly encompassed by paññā, which I think is the classical Theravada position, then how can right view be established without insight?
retrofuturist wrote:Greetings Manapa,Manapa wrote:...due to another group where a similare thread is going on, and a person their seams to hold an almost mahayana Boddhisatva vow view of the importance of rebirth.
Any chance you could provide a link?
Ben wrote:Hi Jechbi
Have a look at the following:
MN 60: Apannaka Sutta: The Incontrovertible Teaching
MN 74: Dighanakha Sutta: To Dighanakha
These probably represent the tip of the iceberg but they are two I have been reading today.
If you don't have Ven Bodhi's translation, please let me know and I'll transcribe the notes.
Manapa wrote:It is a private group so I cant unfortunately.
retrofuturist wrote:Greetings Manapa,
No problems... I was hoping it might provide some context, but that's okay.
Ben wrote:Hi Manapa
They're in A translation of the Majjhima Nikaya. I don't known whether they're in In the Buddha's Words as I don't yet own a copy of that volume.
I'm in the middle of transcribing the notes to MN 60.
Jechbi wrote:What is the classical Theravada position with regard to how one goes about adopting a view that might conflict with views one has had for a long time, perhaps even for many lifetimes? What is the method for adopting this right view?
I had thought that the correct method to address this type of phenomenon would be:
1) To recognize any such thoughts as not right view.
2) To continue with the practices of right speech, right action, right livelihood, right effort, right awareness, right concentration, right intention, and right view to the best of one's ability, recognizing that right view has not been perfected, and that in fact none of these practices has been perfected.
3) And as a result of applying all of these practices, right view will develop according to kamma.
But I wonder if this approach is in line with classical Theravada thought, because an argument seems to be made that the correct method for adopting right view regarding rebirth is to simply accept it, regardless of whether one believes it.
To me that seems like putting the cart before the horse, although I stand to be corrected.
Manapa wrote:I used the Boddhisatta/Tulku references to help with context as that is probably the closest that I know of to how strongly this belief is being expressed without the Mahayana overtones.
Manapa wrote:But is it important to the path?
the unshakable belief that it actually happens, so much so that you go out looking for the evidence ie tulkus, or the stories that abound of children remembering their past lives.
is it that important to the path in the clasical sense?
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text: I saw an old friend today who is being stalked by someone. She has let this person know that she is not interested in him romantically or personally. He is still being persistent. She was asking me for advice on how to handle this situation. I was caught offguard and didn't know what to tell her. What are your thoughts on this?


text: Doctors explained that carbohydrates with a high glycemic index (GI) rating rapidly turn to glucose in the bloodstream, raising chances for diabetes. In one study, researchers tried to lower the GI of white bread using white kidney-bean (Phaseolus vulgaris) extract. Doctors measured blood sugar in 13 participants who ate white bread with or without kidney bean extract and found that GI decreased by 34 percent in those who took 3,000 mg of kidney bean extract powder. Another study found that blood sugar increased less, and returned to starting levels faster in those who took 1,500 mg of kidney bean extract with a small, high-GI meal compared to those who did not take kidney bean extract.


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Anibal sets Tigers record with career-high 17 K's
Righty tops Lolich's franchise mark while Tuiasosopo carries offense
DETROIT -- The Tigers welcomed the team with the best record in baseball by starting a pitcher who had lost his last five starts against the Braves, fielding an offense that had scored just 16 runs in its previous seven games and facing a pitcher who had allowed just three earned runs so far this season.
As the 10-0 victory Friday showed, Anibal Sanchez and the Tigers apparently had the Braves right where they wanted them.
By the time Sanchez dropped a breaking ball past his old teammate and old nemesis, Dan Uggla, for his 17th strikeout of the game, he had provided all the evidence why the Tigers wanted him back when he hit free agency last winter.
"I didn't think for the strikeout," Sanchez said. "I just tried to get a lot of ground balls, stay in the game for a lot of innings. That's what I work for."
Not only did Sanchez get that revenge against his old division rival, he shut them out for eight innings while striking out 17, topping the Tigers' franchise record set by Mickey Lolich on May 23, 1969. He became the first pitcher in the Majors to strike out 17 in a game since Brandon Morrow on Aug. 8, 2010, and the first to do it in eight innings or fewer since fellow Venezuelan Johan Santana in 2007.
All this against a team that had owned him. He hadn't beaten Atlanta in three years, sustaining five straight losses to the Braves as a Marlin. He hadn't struck out more than seven Braves in any of his 17 career meetings. He had just 14 strikeouts against them over his last three starts combined, interspersed between 15 earned runs on 20 hits over 13 1/3 innings.
It's a different lineup with the addition of B.J. Upton and Justin Upton, two high-powered, high-strikeout hitters, along with other role players. As Friday night demonstrated, it's a different Sanchez, too.
"From the times I've faced him, he was a different guy tonight," said Uggla, a former Marlins teammate who became a Braves nemesis a few years ago.
As Sanchez was mowing down Braves hitters -- at least two in every inning but the fourth -- Uggla talked with Braves backup catcher Gerald Laird. He was catching with the Tigers when Sanchez came over last summer.
"He said, 'Once he got over to Detroit last year, he was a different pitcher,'" Uggla said. "I guess that switch turned on and he locked it in."
Uggla was 3-for-10 with two home runs off Sanchez entering the evening. Freddie Freeman, the one other hitter in the Braves' lineup with a history against Sanchez, was 3-for-8 against him.
They stepped to the plate seven times against Sanchez on Friday night. Each time, they went back to the dugout with a strikeout -- four from Uggla, three from Freeman. The Upton brothers, by contrast, fanned just twice.
"I just had more preparation for those two guys," Sanchez said. "I talked with [catcher Brayan] Pena before the game about those two guys. They hit me very good in the past, and I tried to keep the ball down and I said, 'Whatever they hit, they hit ground balls.' That's what we need. We need to put the ball down.
"That's what I did all night, just put my ball down, try to get some strikes. And you see everybody miss, miss. That's it."
Sanchez threw 121 pitches, 84 for strikes. Twenty-seven of those were swings and misses, and they came off of all five pitches in Sanchez's arsenal. Many of them were pitches low, some of them in the dirt.
"Everything was working for him tonight," Pena said. "He was mixing it up. He was attacking the strike zone with his offspeed, and then he was expanding his strike zone. He was making those guys chase because his stuff tonight was unbelievable.
"I think it was one of those nights that when you're behind home plate, you feel comfortable with whatever you put down, especially after a 10-0 lead."
It was the right approach, helped by ample support. While Sanchez struck out seven of the first 11 hitters he faced, the Tigers went to work against previously stingy Paul Maholm. They missed a scoring chance with runners on second and third and nobody out in the second inning, continuing their struggles with runners in scoring position.
Once Torii Hunter and Victor Martinez hit RBI singles in the third, their struggles broke. Matt Tuiasosopo, who made the team to hit lefties like Maholm, opened a 4-0 lead with a bases-loaded single.
Tuiasosopo was one of the few Tigers who had never faced Maholm, so he studied up on him a couple days ahead of time, anticipating the start against a pitcher with a 1.03 ERA entering the game.
"The reason why he's having the success that he's having, he's very crafty," Tuiasosopo said. "[He'll throw] sinker away, cut it in, changeup, then he'll slow down even more with his curveball. So we wanted to make sure we got his pitches up, and we were able to do that today."
Three more singles and another key hit from Martinez, this one a double yanked into the left-field corner, knocked out Maholm. A four-pitch walk from Anthony Varvaro brought up Tuiasosopo again, this time against a righty. His three-run homer closed the book on Maholm, whose ERA tripled with eight runs on 10 hits over 3 2/3 innings.
"For me, there were a few walks that shouldn't happen and a few pitches that didn't happen," Maholm said. "It was kind of a snowball effect. When you look at how [Sanchez] was pitching, it's tough to fight back."
They tried. They missed.
Uggla's record-setting strikeout in the eighth was one of two innings in which all three outs came by strikeout; Sanchez fanned Juan Francisco to end the second with runners on first and second. The only other innings in which the Braves had a runner in scoring position were the third and the seventh.
It was a thorough display on both sides against the Majors' best team.
"They're great," Tuiasosopo said. "They've been playing really good. But you look around this clubhouse, we're a great team, too. As long as we just continue to stay loose, be relaxed and not try to do too much, this is the type of night that we're capable of having."
Jason Beck is a reporter for MLB.com. Read Beck's Blog and follow him on Twitter @beckjason. This story was not subject to the approval of Major League Baseball or its clubs.


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