text:
Location: Avian Disease and Oncology ResearchTitle: DNMT gene expression and methylome in Marek's disease resistant and susceptible chickens prior to and following infection by MDV Author
|Tian, Fei
|Zhan, Fei
|Vanderkraats, Nathan
|Hiken, Jeffery
|Edwards, John
|Zhang, Huanmin
|Zhao, Keji
|Song, Jiuzhou
Submitted to: Epigenetics
Publication Type: Peer Reviewed Journal
Publication Acceptance Date: 3/18/2013
Publication Date: 4/1/2013
Publication URL: http://handle.nal.usda.gov/10113/56470
Citation: Tian, F., Zhan, F., Vanderkraats, N.D., Hiken, J.F., Edwards, J.R., Zhang, H., Zhao, K., Song, J. 2013. DNMT gene expression and methylome in Marek's disease resistant and susceptible chickens prior to and following infection by MDV. Epigenetics. 8(4):431-444. Interpretive Summary: Marek's disease (MD) is a virus induced disease of chicken that continues to threaten the prosperity of the poultry industry worldwide. To better control the disease, genetic and epigenetic (heritable control other than that of DNA) mechanisms underlying of host resistance to MD have been actively sought by the industry and research communities to augment current control measures including vaccination and management of the flocks. This study reports findings of DNA methylation, a chemical modification of DNA chain of specific structural property, differences between a MD resistant line and a susceptible line of chickens post MDV infection. In addition to common DNA methylation patterns, many different patterns were identified between the two lines. The findings suggest DNA methylation may be associated with chicken disease resistance and susceptibility.
Technical Abstract: Marek's disease (MD) is characterized as a T cell lymphoma induced by a cell-associated a-herpesvirus, Marek's disease virus type 1 (MDV1). As with many viral infectious diseases, DNA methylation variations were observed in the progression of MD; these variations are thought to play an important role in host-virus interactions. We observed that DNA methyltransferase 3a (DNMT3a) and 3b (DNMT3b) were differentially expressed in chicken MD-resistant line 63 and MDsusceptible line 72 at 21 d after MDV infection. To better understand the role of methylation variation induced by MDV infection in both chicken lines, we mapped the genome-wide DNA methylation profiles in each line using Methyl-MAPS (methylation mapping analysis by paired-end sequencing). Collectively, the data sets collected in this study provide a more comprehensive picture of the chicken methylome. Overall, methylation levels were reduced in chickens from the resistant line 63 after MDV infection. We identified 11,512 infection-induced differential methylation regions (iDMRs). The number of iDMRs was larger in line 72 than in line 63, and most of iDMRs found in line 63 were overlapped with the iDMRs found in line 72. We further showed that in vitro methylation levels were associated with MDV replication, and found that MDV propagation in the infected cells was restricted by pharmacological inhibition of DNA methylation. Our results suggest that DNA methylation in the host may be associated with disease resistance or susceptibility. The methylation variations induced by viral infection may consequentially change the host transcriptome and result in diverse disease outcomes.


text:
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subset: commoncrawl


text:
21, my birthday is like july cant belive i'm 22 next year wtf...?
21, my birthday is like july cant belive i'm 22 next year wtf...?
39. I have one gear, one speed...
..:: Lvl 90's: 56 ::..
I'm stuck at 20 for quite a while now for some reason :/
20, 21 in April. I have some back problems though, so sometimes I feel way older.
18, born on the 9th of April.
Which happened to be Good Friday. So I'm either Jesus, or the Devil.
http://www.youtube.com/user/TastyGameHub<< Youtube channel http://www.youtube.com/watch?v=5mgoQ...0&feature=plcp<< INSANE DAYZ SHOT Armory Alt
Soon ill run out of fingers and toes to count my age... HOW WILL I KNOW?!
Where's the under 10 option!?
Jk, turning 13 the 16th this month.
I has a debit card looool!
Last edited by Platinus; 2011-09-05 at 05:26 PM.
[email protected] | GeForce GTX 760 | 8GB DDR3-1600MHz | Samsung 840 120GB SSD | 1+2TB HDD | Gigabyte Z68XP-UD3 | Corsair CX V2 500W
NZXT Phantom | 2x 24" 1920x1080, 1x 22" 1920x1080 | Audio Technica ATH-M50x with ModMic | Qpad MK-80 MX Blue | Logitech G600
28, turning 29 in December. Approaching the 30+ territory way too fast
30+ reveals enough, I think...
Useless Fact: I share birthdays with Nick Menza (formerly of Megadeth) and Alexander of Macedonia
22 miles of hard road
33 years of tough luck
44 skulls buried in the ground
Crawling down through the muck
Ah yeah...


text:
Dodgers RBI hosts RBI West Regional
LOS ANGELES - Dodgers RBI will host the 2014 RBI West Regional tournament as five leagues will be competing in the Junior, Senior and Softball Divisions beginning Friday, July 18 and running through Sunday, July 20.
RBI teams will be represented by the host Dodgers (Dodgers RBI), the Los Angeles Angels of Anaheim (Angels RBI), the Arizona RBI, Seattle Parks & Recreation RBI and Nobu Yamauchi RBI from Hilo, Hawaii.
The Softball Division featuring girls ages 13-18 begins play at 8:30 a.m. on Friday, and all games over the three day competition will be held at the MLB Urban Youth Academy located at 901 E. Artesia Blvd. in Compton. The championship game on Sunday, July 20 will begin at 10 a.m.
The Junior Division tournament will feature boys ages 13 to 15, and competition will be held at Algin Sutton Recreation Center (located at 8800 S. Hoover St. in Los Angeles) beginning at 8:30 a.m. on Friday. The championship game will be played at Dodger Stadium on Sunday, July 20 at 9 a.m.
The Senior Division Tournament will pit boys ages 16 to 18, and competition will take place at Jesse Owens Park (located at 9651 S. Western Avenue in Los Angeles). The championship game of this division will be played at Dodger Stadium on Sunday, July 20 at 11:30 a.m.
The complete RBI West Regional schedule:
Softball Division-Friday, July 18: 8:30 a.m. Los Angeles @ Anaheim, 11 a.m. Arizona @ Hilo, 1:30 p.m. Anaheim @ Arizona, 4 p.m. Hilo @ Los Angeles. Saturday, July 19: 8:30 a.m. Arizona vs. Los Angeles, 11 a.m. Hilo vs. Anaheim. Sunday, July 20: 10 a.m. 2 teams with best records. All games at MLB Urban Youth Academy.
Junior Division-Friday, July 18: Hilo @ Los Angeles, 11 a.m. Anaheim @ Arizona, 1:30 p.m. Arizona @ Hilo, 4 p.m. Los Angeles @ Anaheim. Saturday, July 19: 8:30 a.m. Hilo vs. Anaheim, 11 a.m. Arizona vs. Los Angeles. Sunday, July 20: 9 a.m. 2 teams with best records. Friday and Saturday games at Algin Sutton. Sunday championship game at Dodger Stadium.
Senior Division-Friday, July 18: 8 a.m. Los Angeles @ Anaheim, 10:30 a.m. Arizona @ Seattle, 1 p.m. Anaheim @ Arizona, 3:30 p.m. Seattle @ Los Angeles. Saturday, July 19: 9 a.m. Arizona vs. Los Angeles, 11:30 a.m. Seattle vs. Anaheim. Sunday, July 20: 11:30 p.m. 2 teams with best records.
Friday and Saturday games at Jesse Owens Park. Sunday championship game at Dodger Stadium.
About Dodgers RBI
Dodgers RBI is a comprehensive, urban youth baseball program for boys and girls, ages 5-18. Working together with local organizations, parents and volunteers, Dodgers RBI currently offers 2,700 youth the opportunity to learn and enjoy the games of baseball and softball with special emphasis on education, recreation and healthy habits for young people. Dodgers RBI is a cornerstone program of the Los Angeles Dodgers Foundation (LADF), the official charity of the Los Angeles Dodgers. LADF provides uniforms and equipment, recruitment assistance, cash grants and education/health resources to all teams. Additionally, Dodgers RBI also provides resources to ensure increased participation by youth ages 13-18 and places special emphasis on African- Americans. Dodgers RBI is part of MLB's RBI program. The RBI program has provided a path for many players to enter the college and professional game. Alumni of LA RBI who currently play in the Majors are Coco Crisp (Oakland A's) and James McDonald (Chicago Cubs).
About RBI
The RBI (Reviving Baseball in Inner Cities) program, which is in its 26th year of operation and began in Los Angeles, is administered by Major League Baseball and is designed to give young people from underserved and diverse communities the opportunity to play baseball and softball, encourage academic achievement and success, and teach the value of teamwork and other important life lessons. RBI currently serves more than 220,000 young men and women in more than 300 programs established in approximately 200 cities worldwide. MLB and its Clubs have designated more than $30 million worth of resources to the RBI program, and all 30 Clubs support RBI leagues. For more information about the RBI program and the RBI World Series, please visit MLB.com/rbi.


text:
Art Nouveau
Art Nouveau, the name alone suggests a style of art that is innovative and incomparable. Regarded as one of the significant art periods nowadays, Art Nouveau takes on the influence of countless artists of the 19th century like Mucha and Klimit.
Decorative patterns
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Agony of choice
ARTFLAKES provides poster of four dimensions. It is totally up to your needs and taste to choose the desired product type. Your selected poster will be printed on high quality paper, so you are sure to love it. In any case, ARTFLAKES provides a money back guarantee, so happy shopping!


text:
Genoa Country Store rocking toward Valentine's Day
January 22, 2013
Only months into their third year of business, the operators of the Genoa Country Store are in the position every small business owner wants to be in."We bought a business that was losing money, and now it's profitable," said 35-year-old Genoa resident Derrick Van Der Jagt.Derrick's wife Kierstin purchased the landmark store in the fall of 2010. Since then the couple have ramped up offerings and expanded market share."We bought the store, but the deli is more our market area," Derrick said. "We make sure we have the best ingredients we can, including certified Angus roast beef from Ranch No. 1 in Genoa. We have homemade soups all the time. It's been working out well for us."The store will be hosting a Valentine's Day bash of sorts 11 a.m.-4 p.m. Feb. 9-10. The event has been organized by local artist Russel Ketenjian and will include chocolate, wine tasting, and guitar and oud playing, ballads and blues.There is no cover charge.The store is located at 2299 Main Street, Genoa. For more information, call 782-5974.
The Northern Nevada Development Authority is hosting a breakfast to introduce the 2013 Agriculture Report to the state. This report has involved dozens of individuals along with University of Nevada, Reno, and months of revisions to establish where Nevada is at and what the future holds. Gov. Brian Sandoval and State Director of Agriculture Jim Barbee will be sharing some of the vital information coming out of this report and how this $5.3 billion industry impacts every part of the state. The meeting is today at 7 a.m. in the Carson Nugget.Some highlights of the report: Clark County leads the state in agriculture production; Nevada imports most of the beef it consumes; Southern Nevada is the leader in consumption of agriculture.For information regarding copies of the report, contact Lee Bonner at firstname.lastname@example.com.
Minden resident Erika Evans has joined the team of stylists at Drago's Salon & Day Spa in Minden.Evans performs cosmetology, hair coloring, cutting, styling, and make-up. She is available 9 a.m.-5 p.m. Tuesday-Saturday.The salon is located at 1667 Highway 395, Minden.For more information, call 782-5909.
Financial services firm Edward Jones ranked No. 8 in Fortune Magazine's "100 Best Companies to Work for 2013," the firm's 14th appearance on the list, according to four Carson Valley financial advisors.Currently, Edward Jones has 4,630 positions available throughout the country, mostly for financial advisor and branch office administrator. Each Edward Jones branch office includes one financial advisor and one branch office administrator who work one-on-one with clients in the communities where those clients live.To pick the 100 companies, Fortune partners with the Great Place to Work Institute to conduct an extensive employee survey. Two-thirds of a company's score is based on the results of the institute's trust index survey, which is sent to a random sample of employees from each company. The survey asks questions related to their attitudes about management's credibility, job satisfaction, and camaraderie. The other third of the scoring is based on the company's responses to the institute's culture audit, which includes detailed questions about pay and benefit programs and a series of open-ended questions about hiring practices, internal communications, training, recognition programs and diversity efforts.Edward Jones' 12,000-plus financial advisors work with nearly 7 million clients to create long-term investment solutions that emphasize a well-balanced portfolio and a buy-and-hold strategy. The company website is http://www.edwardjones.com, and its recruiting website is http://www.careers.edwardjones.com.


text:
Shh... Nobody Knows I Am Gay Darren Women T-Shirt
Product Color:
Product information
The Women T-Shirt Shh... Nobody Knows I Am Gay Darren is our old-school favorite. Perfect for use in sports where you are bound to sweat and need wide range of movement. Short sleeves to let cool air in on those hot and sunny days. Also great for every day use and to show everyone your love for Shh... Nobody Knows I Am Gay Darren.
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Sku: TC2BR0000008011717170621CRGO00000


text:
Another love poem from the European Left.
A few days after September 11, I saw a quote from Gunter Grass on a Manhattan lamppost. In those dark days, the lampposts and walls that weren't covered in missing persons posters were decorated with the hysterical pamphleteering of the left urging us to blame ourselves for the attacks. The quote has long since been lost to memory, buried under smoke and ash, a green parrot perched on an empty staircase and crowds thronging on foot across the bridge.
The quote itself, like the latest Grassian screed, does not matter. Grass, like Gandhi and King, was one of the favorite go-to guys for the left's sticky sheets of paper. When you want to write a suicide note, then you reach for a line from Sylvia Plath or Emily Dickinson, but when you want to write a national or civilizational suicide note, there's always Gunter Grass.
As a writer, Gunter Grass is a blacksmith, hammering together graceless and shapeless lumps that aren't good for much except hitting people over the head. Take his latest masterpiece which has for a brief shining moment gotten people outside Germany and Sweden to mention his name in conversation. You don't have to know German to recognize that, "Es ist das behauptete Recht auf den Erstschlag der das von einem Maulhelden unterjochte" is not exactly Die Lorelei. In a fitting irony the author of the Tin Drum has a tin ear.
Like Die Lorelei's protagonist, Gunter Grass writes about being filled with unnamable emotions, but instead of seeing water nymphs combing their hair while ship captains ram their boats into the rocks, Grass is attempting to impress audiences with his bold struggle against Jewish accusations of bigotry to forewarn us about the threat of the Jewish state.
Grass, like so much of the German left, sees Nazis everywhere but in the mirror. The only lesson that he and his comrades have drawn is that they were wrong to march right, when they should have marched left. It does not occur to them that they should not have been marching at all and that the marching under red banners was the whole problem to begin with.
On the thirty-first anniversary of Kristallnacht, the progressives of the German terrorist left plotted to bomb a Berlin synagogue where a Kristallnacht commemoration was taking place. They didn't succeed, but their colleagues on Air France Flight 139 did, staging their own Aktzion, separating the Israelis from the non-Israelis and deciding who would go left or right.
Bose, the leader of the German Entebbe hijackers, who had told the hostages that he was not a Nazi, just an idealist, had proposed assassinating Nazi hunter Simon Wiesenthal. That plot, like bombing a synagogue's Kristallnacht commemoration, seemed more like it might be up a Nazi's alley. Another symptom of how the German left could not help goosestepping right.
The answer to the unspoken thing that Gunter Grass dares not speak of may lie in a letter from the leader of another German leftist terrorist cell, Dieter Kunzelmann, who while sipping coffee with Muslim terrorists in Jordan, wrote home that, "The German left must overcome its Judenknacks" or hangups about Jews. By this little Dieter did not mean that the German left should stop hating Jews, he meant that it should learn to feel good about hating Jews.
Bombing the synagogue on Kristallnacht would help Germany get rid of its "Vorherrschaft des Judenkomplexes", he wrote, which means something like the Supremacy of the Jewish Neurosis, Bombing a synagogue would help Germans break through their feelings of guilt and emancipate the German left from feeling any hesitation about killing Jews. The provocateurs of the left who had dedicated themselves to the war against bourgeois hangups about orgies and communal property would help break one more wrongheaded bourgeois taboo. Much like an icon of the German left confessing to having served in the SS and writing a poem that features him working out his own "Judenknacks" right on the page.
Gunter Grass is more of a moderate than Dieter Kunzelmann. Rather than tackling the Judenknacks head on by bombing a synagogue on Kristallnacht or shooting Simon Wiesenthal in the head, he takes the hack's route by treading the well worn ground of spinning the wheel of history until the Jews become the new Nazis. They have uniforms don't they, and an army and bombs. Such an observation wouldn't have been all that novel in the seventies, for Grass to pretend that his whispered take on it is something daring and shocking brands him as a true hack.
You do not come away from "Was Gesagt Werden Muss" having learned anything more about Israel or Iran than you did going in, but you learn something about what a fine fellow that Gunter Grass is, why he dares to say what no one else dares to say as he reclines on his own therapist's couch and achieves a breakthrough in tackling the Vorherrschaft des Judenkomplexes that plagues the left.
Mein Kampf wasn't about the Jews or England and France, it was about what a great man that Adolf is and why you should consider him for dictator for life. The European left's Anti-American and Anti-Semitic hiccups have little to do with the red, white and blue or the blue and white. They have to do with how impressive all the speakers are in taking on the Great Satan and the Little Satan. Down with General Electric, down with the A-Bomb, down with the Synagogue. Up with whoever is shouting through a megaphone about boycotting Israeli walnuts or American rockets.
The current shouter through the megaphone isn't just Grass, it's Sigmar Gabriel, the head of Germany' Social Democratic Party, a party that Grass has more than a passing affinity for. The elections scheduled for next year will determine a great deal and the attacks on the sale of submarines to Israel are aimed at Chancellor Merkel. Attacking Merkel for pandering to the Jews is a bit of 1930's politics, but that's just part of getting over the Judenknacks.
It's not about the left being Anti-Semitic, it's about it being socially acceptable for the left to be Anti-Semitic. And it's about the "courage" of leftists who dare to take on the bourgeois post-Holocaust hangups and switch them around so that the Jews become the Nazis, the Nazis become the Jews and the Mullahs become the Uberjews. The Jews are irrelevant except as a means for the left to rid itself of all rules and morals on the path to total revolutionary commitment.
"Raise high the red flags," the Battle Hymn of National Socialism went, "For German labor we will clear the path to freedom." Those red flags have not changed much since. The Blutfahne, the blood flag covered supposedly in the vital fluids of dead Nazis killed during the Beer Hall Putsch under which Nazis swore in new recruits. Or the red flag of Soviet Union memorializing the blood of the martyrs of revolution. Or the red tulips of the Iranian flag which represent the blood of martyrs.
They are cheering Gunter in Berlin, in Moscow and Tehran, not to mention London, Paris and Boston. Not because he has said anything terribly daring, but because he has thrown a stone at a window. And it isn't the size of the stone, it's the breaking of taboos. And when enough taboos have been broken, then the red flags will freely wave again.
Freedom Center pamphlets now available on Kindle: Click here.


text:
So, what if Betty takes an aggressive stand and fights tooth and nail for Joseph? How does this attitude
affect the actions/reactions of her daughters?
Created: 08/25/11
Replies: 5
Join Date: 08/11/11
Posts: 69
Join Date: 10/16/10
Posts: 84
Joseph seems so easily influenced that I wondered what would happen if Betty HAD fought for him. Yours is a good question. I think he would have come back to her, and I think Annie and Miranda would have supported her in her more aggressive stance. Both Annie and Miranda are strong women who are used to getting what they want, or at least - in the case of Annie - standing up for themselves, so I think Betty would have had their full support.
Join Date: 08/11/11
Posts: 69
Sara, I certainly appreciate the positive response. Although I appreciated and even admired Betty's gentle
lady-like manner through her ordeals, I wanted Betty to fight, and if the truth be known, my money would
have been on her! I believe Betty would have been a positive role model for her girls and other women who "lose" husbands to other women if she had fought for Joseph. Maybe that story is another
novel??? Thanks for the thoughtful response.
Join Date: 04/24/11
Posts: 16
I think the story woiuld have been more interesting. Because Betty did nothing, Felecity was able to influence Josie. I think Josie really loved Betty but might have been bored with the relationship. To me, he didn't show that much interest in Felicity.
Join Date: 07/24/11
Posts: 38
I also feel that if Betty had fought for him she would have won Josie back. We see brief moments in the book where Josie seems to reflect back on what he has lost and see Felicity for the gold digger that she is. You can't help but wonder if she would have died by the end of the novel if she had stood her ground and refused to leave the apartment.
Join Date: 08/11/11
Posts: 69
Like you, I felt the official end of the marriage, indeed ended Betty's life as well. Without the fight, there
was no will to continue-it sounds a bit elementary, but I believe it to be so true. The apartment did seem to be Betty's "root", her life line.
Please login to post a response.


text:
The dysfunctional Hayward school board's squabbling must end. At a time of horrendous test scores and mounting financial challenges, students and parents deserve mature leaders.
Fortunately, the terms of the three board members at the center of the storm are up, and two are not seeking re-election. The third, Luis Reynoso, should be replaced.
That leaves six other candidates. It's not a strong field. No candidate has a solid handle on the district's finances, nor substantive ideas for putting the district back on track. But if they can get along, maybe the board and administrators can find solutions.
We opt for candidates familiar with the district, education or both who are willing to hold teachers accountable for performance: Annette Walker, who holds a doctorate in education and works as a college admissions administrator; John Taylor, a teacher for 17 years and former Alameda County teacher of the year; and Heather Reyes, a parent who has served on a district financial advisory group.


text:
Study of Clinical Non-inferiority of Actparin® (Laboratorio Bergamo) Compared to Heparin Sodium (APP Pharmaceuticals), in Patients With Chronic Renal Failure
The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified April 2011 by Laboratório Químico Farmacêutico Bergamo Ltda..
Recruitment status was: Not yet recruiting
Recruitment status was: Not yet recruiting
Laboratório Químico Farmacêutico Bergamo Ltda.
Azidus Brasil
Information provided by:
Laboratório Químico Farmacêutico Bergamo Ltda.
ClinicalTrials.gov Identifier:
First received: April 28, 2011
Last updated: April 29, 2011
Last verified: April 2011
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
The purpose of this study is to investigate clinical non-inferiority, pharmacodynamic effect and safety of Actparin® (heparin sodium - Laboratório Químico Farmacêutico Bergamo Ltd.) compared to Heparin Sodium (APP Pharmaceuticals) in patients with renal failure under hemodialysis treatment.
|Chronic Renal Failure
|Biological: heparin sodium
|Phase 3
|Study Type:
|Study Design:
|Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Investigator)
Primary Purpose: Prevention
|Official Title:
|Study of Clinical Non-inferiority of Actparin® (Laboratorio Bergamo) Compared to Heparin Sodium (APP Pharmaceuticals), in Patients With Chronic Renal Failure
Resource links provided by NLM:
MedlinePlus related topics: Blood Thinners Kidney Failure
Drug Information available for: Heparin Heparin sodiumU.S. FDA Resources
Further study details as provided by Laboratório Químico Farmacêutico Bergamo Ltda.:
Primary Outcome Measures:
- Effectiveness in prevention of clotting in the extracorporeal circuit during hemodialysis [ Time Frame: 4 weeks (12 consecutive sessions) ]
Secondary Outcome Measures:
- Pharmacodynamic activity of heparin observed through aPTT marker [ Time Frame: 4 weeks (sessions 1, 6 and 12) ]
- Safety in use of heparin by monitoring adverse events [ Time Frame: 5 weeks (12 consecutive sessions + 1 post treatment session) ]
|Estimated Enrollment:
|Study Start Date:
|October 2011
|Estimated Study Completion Date:
|February 2012
|Estimated Primary Completion Date:
|December 2011 (Final data collection date for primary outcome measure)
|Assigned Interventions
|Experimental: Actparin® - Laboratorio Bergamo
Biological: heparin sodium
5000 UI/mL
|Active Comparator: Heparin sodium - APP Pharmaceuticals
Biological: heparin sodium
5000 UI/mL
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Patients research that agree to participate in the study and sign the informed consent form;
- Patients aged over 18 years, both sexes, regardless of color or social class;
- Patients with impaired renal function in chronic hemodialysis schedule of at least 3 times a week and giving the use of heparin in the prophylaxis of thrombosis in the system;
- Patients with laboratory results within specified acceptance criteria.
Exclusion Criteria:
- Patients who are taking part or took part in another clinical investigational study within 12 months;
- Hypersensitivity to heparin sodium and/or benzyl alcohol;
- History of active hemorrhage with alteration of blood coagulation, such as genetic disorders of coagulation system;
- History of disease that could aggravate or terminate the clinical manifestations, such as active peptic or gastric ulcer;
- Severe liver disease;
- Patients in cancer treatment;
- Pregnant and lactating women;
- Use of glucocorticoids over physiological dose;
- Use of other anticoagulants;
- Patients undergoing any surgery performed less than 15 days;
- History of non response or exacerbated response to heparin sodium;
- Patients who do not adapt to 150 UI/kg dose.
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01346215
Please refer to this study by its ClinicalTrials.gov identifier: NCT01346215
|Contact: Marcelo A. C. Orlandi , Dr.
|Instituto de Nefrologia de Campinas
|Not yet recruiting
|Campinas, São Paulo, Brazil
|Contact: Marcelo Orlandi
Sponsors and Collaborators
Laboratório Químico Farmacêutico Bergamo Ltda.
Azidus Brasil
|Principal Investigator:
|Marcelo A. C. Orlandi, Dr.
|Instituto de Nefrologia de Campinas
More Information
Additional Information:
Keywords provided by Laboratório Químico Farmacêutico Bergamo Ltda.:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on September 21, 2017
Additional Information:
|Responsible Party:
|Marcelo A. C. Orlandi, Instituto de Nefrologia de Campinas
|ClinicalTrials.gov Identifier:
|NCT01346215 History of Changes
|Other Study ID Numbers:
|Study First Received:
|April 28, 2011
|Last Updated:
|April 29, 2011
Keywords provided by Laboratório Químico Farmacêutico Bergamo Ltda.:
renal insufficiency, chronic
extracorporeal dialysis
fibrinolytic agents
Additional relevant MeSH terms:
Renal Insufficiency
Kidney Failure, Chronic
Renal Insufficiency, Chronic
Kidney Diseases
Urologic Diseases
Calcium heparin
Fibrinolytic Agents
Fibrin Modulating Agents
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Bees legend Kevin O'Connor admitted promotion to the Championship made pain of relegation worthwhile, writes Stuart Amos.
The 32-year-old, who will take up a player-coach role at Griffin Park next season, can break the 500 league appearance barrier for the club should he feature in Saturday's trip to Colchester United and the visit of Stevenage on May 3.
O'Connor started his career with the Bees in 2000 – taking in relegation to and promotion from League Two, with the odd play-off defeat along the way – and admitted elevation to the second tier was the icing on the cake
"You experience relegation and how low you felt and then it comes to Friday and it makes it all worthwhile," he said.
"It is a great feeling and memories that will live with me forever. It is a great time to be at a club going places."
He added: "I'll sit down with the manager to discuss my role. There are great coaches to learn from here.
"It is going to be really interesting and exciting."


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Trying to develop my FH shot. Previously it was mostly to get out of trouble, and approaches. Ive been working on it lately and have changed my grip from a 1 finger (only on drivers, 2 finger everything else) to a 2 finger stack w/ my middle finger on the rim and index over the back of the middle finger. It took a few rounds to get used to but it feels right now, and i am experiencing some more distance then i previously was getting with a bit more accuracy when i have a solid throw.
My biggest hurdles are currently;
Footwork- atm, my approach is very slow, 1 step or a hop/x step, if not standing. I know im missing out on leverage and losing power here. I saw Woj's video and it helped a lil, maybe ill re watch, any other insight or help would be welcomed.
Hip/shoulder timing with my throw- I feel like this timing is off currently and its costing me D as well as accuracy and potentially teaching me bad habits w/ my form that still isnt that great for this shot.
Snap w/out OAT- atm, i am using preds, PD's, and occasionally Forces for FH shots off the tee. Im not sure if its a product of the LSS of these discs or my lack of snap, but on what i consider a fundamentally sound throw, ill get a slight turn, like a really tight S, and a penetrating fade and i can reliably throw to 225-250' and this is about 80 pct power. Any harder and my terrible form/bad footwork/OAT starts showing badly.
I would like some pointers on how you throw w/ power without wrist roll. I feel like the harder I try the worse the throw is, but I can only throw so far to this point with the "minimal effort is better" thing. And would like to throw farther more accurately.


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NEW YORK (TheStreet) -- Gene C. Collins figures virtual, Web currency Bitcoin is entering its, uh Deep Throat phase.
"When I heard about Bitcoin, it sounded like a bunch of kids having fun," said the chairman of the investment committee for the University of Toledo, a $400 million endowment that helps fund the Ohio-based educational institution of roughly 50,000 students and faculty. "But now that it's passing for real money, something significant and ugly has happened."
"Bitcoin is become financial porn."
Collins and I, over coffee in his Rye, N.Y. home, were breaking down how Bitcoin uses open-source, peer-to-peer digital technology, similar to how music and desktop data is often shared, to move money around the globe. We were shaking our heads over recent announcements that sports teams such as the NBA's Sacramento Kings, carmaker Tesla and even law enforcement officials are treating this virtual currency as real currency.
Collins is my kind of currency expert. Over the half-decade we've talked, I have always admired his flesh-and-blood street smarts in growing the hundreds of millions he manages for his Toledo-based alma mater. Collins knows financial technology. Back In the mid-1980's, he was a major player in the Bitcoin of that era: He ran the mortgage-backed securities operation for A.G. Becker Paribas, to gussy it up for a lucrative sale to Merrill Lynch in 1984.
"What Merrill was paying for was the automated trading processes we developed," he explained. "We were some of the first to do that."
Collins has done tens of thousands of deals, touched billions of dollars and can talk smack about everybody from Sandy Weill back when Citibank was nothing more than Commercial Credit Co. to Michael Bloomberg when he just another hack looking for money for his nutty terminal idea. And his investment philosophy is easy for investors to love: "I am all about exactly one thing: stocks," he said. "When money is this cheap, where else can you put capital to find return?"
So how does Collins sum up Bitcoin? One word: terrifying.
"If you're mistaking Bitcoin for real currency, I have a great deal on tulips for you," he said. "Because when the liquidity evaporates for this stuff -- which let's not pretend can't happen in our post-mortgage meltdown world -- flower bulbs are going to be 10 times worth more than any pile of Bitcoins."


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New market forecasts from Mintel predict cosmetic sales in the US will rise as a result of the recession. Moreover, Mintel anticipates a higher growth rate for makeup now than it did just eight months ago (10% over the next five years versus 7%).
Mintel's re-forecasting of previously published research reports has uncovered which beauty and personal care markets are recession-proof and which ones are being stimulated by the poor economy. Though the beauty and personal care sector is struggling overall, Mintel sees some very bright spots, including color cosmetics.
"Many women have a deep emotional tie to their appearance, so cosmetics are a non-negotiable," said Joan Holleran, director of research, Mintel. "These women may trade down on other purchases or forgo expensive vacations, but they will still treat themselves to small, feel-good luxuries like makeup and beauty products."
Holleran points to another segment that is expected to fare the recession well: antiaging beauty. Mintel expects sales of antiaging skin care products to increase 20% during the next five years. One year ago, Mintel forecast 44% five-year growth, but the adjusted market forecast is significant given the current economic climate.
Mintel also predicts healthy growth for sun care products, with sales expected to increase 36% from 2008 to 2013. This is a slight decline from Mintel's original market forecast of 41% growth, but it still shows people continuing to follow dermatologists' advice to use sunscreen daily.


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Sam Wilkes is development director and the only paid staff member at Youth First Texas.
On Sunday he appeared on Lambda Weekly to talk about bullying and how groups like YFT can help.
Wilkes said an estimated one-third to on- half of teen suicide attempts are by LGBTQ youth.
The Centers for Disease Control lists suicide as the third leading cause of death of people ages 15 to 24, just behind accidents and homicide. More than 4,000 young people commit suicide every year — that's one every two hours.
According to estimates, 100 to 200 attempts are made for every actual suicide.
On Friday, at a rally in Lake Cliff Park in Oak Cliff to support safe schools, Wilkes spoke about the youth who attend YFT.
"These are youth who are marginalized and have no other place to turn," he said. "In fact many of them are homeless because they feel they are safer on the streets than they are in their own homes."
On Lambda Weekly, Wilkes told his own story and talked about why he's so passionate about helping other young people.
When he was 18, Wilkes' mother asked him whether he was gay. Although Wilkes knew he was different from the time he was 12, he wasn't ready to come out. So he gave his mother an answer that was ambiguous and non-committal.
The next day, his mother handed him a letter that said he was no longer welcome in the house.
Wilkes was fortunate because he already had a job working at a restaurant. He had friends who let him crash on their sofa for several months until he could save enough for an apartment. On his own, he managed to finish school. To this day, he said, his relationship with his parents is nonexistent.
But not all youth are even as fortunate as he was, he said. He called his job at Youth First Texas the best opportunity anyone could have.
Wilkes said more than half of youth at YFT have contemplated or attempted suicide before coming to the center. But after they become involved at YFT and meet other LGBTQ youth, depression and risky behavior decreases tremendously.


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HAD it not been for a series of unfortunate injuries, Swindon Town manager Mark Cooper believes Ryan Mason would by now be a regular fixture in the Tottenham first-team squad.
Mason, who is expected to resume full training with Town on Monday after missing three weeks of action with a side strain, is on loan at the County Ground until the end of the season.
Highly-rated by Spurs boss Tim Sherwood, the 22-year-old has previously spent time out at Millwall, Doncaster Rovers and Yeovil Town as he gains a footing in the game but Mason has been plagued by bumps, bruises, knocks and sprains along the way.
During his time in Wiltshire, the creative midfielder has had to deal with ankle and thigh issues as well as his most recent problem, all of which have combined to stifle his progress.
Cooper, however, still feels the England age-group international has a big future ahead of him and without his bad luck the Town manager thinks Mason would already be gracing a much bigger stage.
"The kid deserves a period of injury-free time so he can show how good he is on a football pitch instead of worrying about where his next one is coming from," he said.
"He's been really unlucky. He's had his injuries and they've stopped him. I think if he hadn't been injured he'd be playing in Tottenham's first team now. He's that good technically,.
"I know Tim rates him really highly and if he hadn't have had these injuries he could be in their first team. If we can get him ready and right for 15 games we've got a hell of a player on our hands.
"He's still a young lad, he's got plenty of time and seasons and I'm sure that somewhere along the line he'll have an injury-free spell where he can really show his amazing talent.
Spurs have allowed Mason to undergo his recovery under the supervision of Swindon physio Paul Godfrey and sports scientist Michael Cooper.
"I would anticipate he'd be back in full training for the start of next week," said the Town boss.
"What we're not going to do is make him train on Monday and play on Tuesday. We've got to make sure he's 100 per cent fit, like we have done, and hopefully he can have a spell injury-free.
"Spurs have been more than happy for Paul and Mike to do his rehab and Ryan has been more than happy to do his rehab here."


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Posted 5 years ago
(31 items)
This was one of my first flea market finds after just settling into the new house down in Fla. A pair of 19 50's atomic candy dishes .They measure at 8 " tall and 6 " wide, in mint condition All gold and black paint design is crisp and intact. Wonderful geometric "Spirograph" type design .When I found these I immediately grabbed them, Checked them out for damage and expected to pay 20 30 bucks for them. I ask the guy how much, He said 3 bucks, Needless to say I started foaming at the mouth.
Not sure who they might be, I don't believe they are George Briard,I'm thinking possibly Culver or Dorothy Thorpe.


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Paul Graham has just published an excellent article called "You Weren't Meant to Have a Boss". He talks about many of the same ideas I have talked about on this blog, and why it's best to work in small organizations if that is what most appeals to you, and works for your personality. This is […]Read More...
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Top 10 heels of all-time!!
by, 06-14-2012 at 03:09 PM (13041 Views)
I did the best on the mic both now and all-time. I decided to take it a step farther by acknowledging the best heels of all-time. Who makes the top 10 cut?
1.Iron Shiek-A heel that spits in the face of America and what it stands for. During the 80s, they certainly took it personal. I was considering having Sgt.Slaughter share this slot with Shiek because it was the same gimmick, but I decided against it.
2.Vince McMahon-After that screwjob at the 97 Survivor Series along with the promo Bret screwed Bret claiming he had no sympathy for him. That nailed it in the coffin making him one of the top heels in the company. Vince/Austin rivalry to me is the best rivalry of all-time. Wanting to see Vince get his buttkicked to me is the one of the main reasons why WWE got back in the Monday Night War and eventually defeated WCW.
3.Hollywood Hogan-Turning on his old friends and joining the NWO was of course one of the main reasons why WCW did beat WWE in the ratings 80+ weeks straight. Claiming he only cared about the money and lieing to his fans is what really propelled the heat. Throwing garbage at him after turning on WCW. Spraying letters of NWO not only on his defeated opponents, but on the World title. NWO ended up having tons of members that it felt like WCW had very little. NWO outnumbering and beating up WCW guys week after week.
4.HHH-I never really did like HHH and I don't now. He was never a good face, but he was a great heel. Best time for HHH as a face was in 98 leading DX vs the Nation. I know some people believe Rock's best rivalry was with Austin, but I believe his best rivalry was with HHH during the McMahon/Helmsley era. HHH had tons of great fueds with Mick and Rock. He seemed to always beat the guys who you wanted to win whether it be RVD, Mick, Rock, Austin, and whoever else. Like who rooted for HHH over the Rock during the days of 2000? I certainly wasn't. Using sledgehammer, boss's daughter, and DX/Evolution members to retain his championships.
5.Kane-I debated 3-5 on the listing. During his 2003 run when he took his mask off. He scared the crap out of me. LOL! Setting JR on fire, getting up no matter who hit him with their best moves, sitting up after limo into an 18 wheeler and attacking the doctors in the process, Tombstone Linda McMahon and frying Shane's area. That was all in the matter of like a month or 2.
6.Roddy Piper-probably should be higher on the list, but I have him here. One of the many reasons I don't like Hogan is because he believes others like Piper didn't help make the success of Wrestlemania. He believes only him and Vince. I believe Piper was a huge part of the reason why the first few Manias were successful. He was the top heel in the company in the first 2. My favorite match of Wrestlemania 2 was between Piper/Mr.T mainly because he gots DQ'd instead of getting defeated by a celeb. Fans were chanting for Roddy as he went to the back. Piper would have Piper's pit embarrassing every single person from a midget to Andre The Giant. He was the guy people wanted to see get his butt kicked.
7.Ric Flair-The great part of Ric Flair was he made wrestlers look better than they were in the ring. He would help get the fans to go nuts for the face no matter who the face was. I think the greatest heel moment of his career was turning on Dusty Rhodes after Dusty came out to help Flair. Fans around the ring were trying to get in to help Dusty. They jumped over the barracade. I mean these fans wanted to beat the crap out of Ric Flair for turning on Dusty. I believe that was also the beginning of the 4 Horsemen. Correct me if I'm wrong guys. Flair bragged on the mic being the best dressed, being the best in the biz, and so forth which really made his rivalry with Dusty probably his best rivalry of his career.
8.JBL-The great thing about JBL was he was very smart about how he wanted to do his main event run. He demanded no shirts to be made so fans won't cheer him. He did several great heel things during his 10 month reign on SD always having help winning championship matches. Whether it be Kurt Angle grabbing Eddie's leg during their cage match, Heidenreich costing Taker every title match, win barbwire steel cage match after getting chokeslammed through the ring, and so forth. Probably the biggest heel moment of his career was causing Eddie's mother to have a heart attack in the middle of the ring. Probably the funniest moment was that promo he did with the mexicans making them go back accross the border.
9.Edge-I believe Edge really took his game to another level during 2004 at Taboo Tuesday.HBK voted in which meant the other two had to compete in a tag team title match. Edge left his partner in the middle of the match speeding away in his car. Partner did end up winning the tag titles, but later that night he also cost HBK his World title oppurtunity vs HHH. I believe he received the most ultimate heat when he was with Lita during the summer of 2005. Cashing in MITB 2x after Taker and Cena had been put through hell in cage and Chamber matches. Keeping the world title by DQ just about every time, cheating to win, and having guys who look like him take the bumps so he can rest and steal the victory.
10.Kurt Angle-I know several folks may be upset with HBK not making this list, but I feel Kurt was the better heel. "You suck" chants lasted for several years. Kurt being an American hero getting booed while fans cheering guys who raise hell. LOL! Kurt used the 3 I's and was sort of a dork at times. My favorite moment in Kurt's career was on Raw in 2005 the night he came out complaining about the "You suck" chants refusing to wrestle in front of those fans. Kurt did wrestle later that night when Eric agreed to allow him to have them be censored while they chanted "You suck".
Without a doubt HBK was one of the best heels, but he didn't make my cut. Hope you don't hold it against me even though I know some will. That my friends are my top 10 heels all-time.


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DUDLEY Sports could take a big step towards securing their West Midlands League Premier Division status this weekend.
They travel to bottom side Bustleholme this Saturday knowing a win would extend the gap between the two sides to 12 points.
The fixture comes on the back of a much-needed 2-1 home win over Bilston last weekend and manager Andy Gore thinks another victory would go a long way to making sure Sports stay up this season.
He said: "The Bilston game was a massive win for us. It was our first win for six or seven games and we really needed that. It now gives us something to build on.
"If we can get back-to-back league wins by beating Bustleholme it will make life a lot easier for us. Our aim now should be to be more consistent with our levels of performance and see if we can get another three points in quick succession."
Last weekend's victory against Bilston saw both James Padden and Kennedy Digi hit their first goals for the club.
Before Saturday's game against Bustleholme, Dudley were set to play Bromyard away in the cup on Tuesday night. Gore said he would be looking to give some of his team's fringe players a run out. He has a full squad to pick from except Andrew Blakeley who is still a few weeks away after suffering a broken nose.


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|Trad, TR, 1 pitch
|YDS: 5.7 French: 5a Ewbanks: 15 UIAA: V+ ZA: 13 British: MVS 4b [details]
|Page Views:
|Submitted By:
|Jim Cormier on Aug 1, 2001
|Comments on Admission Crack
|Add Comment
|Show which comments —
By Anonymous Coward
Dec 2, 2001
|It is really pushing it to call this a 5.7, I thought more of a 5.5.. just my two cents.
By George Bell
From: Boulder, CO
Feb 10, 2002
|This is a fun crack - much easier than the face route to it's left. It's ridiculous to give them both a 5.7 rating!
By Peter Gram
From: Cupertino, CA
Mar 27, 2003
rating: 5.5 4b 13 IV+ 11 MS 4a
|The only hard move is getting into the crack at the bottom. In most areas this would be 5.4 or under.
By retroClimber
Apr 17, 2006
rating: 5.7+ 5a 15 V+ 13 MVS 4b
IMO the other comments about this route really sandbag it. Yeah, I'm not a great climber but I've been known to haul my ass up the occasional 5.10.
The East Slab of the Dome is 5.6. The last time I climbed the Wind Ridge on the Wind Tower (start from the tree, not direct) it was rated 5.6.
The first 40 feet of this route is WAY more difficult than any move on either of these routes. The first move is easily 5.7 plus and perhaps 5.8 when compared to the 5.8 routes at Mary's Lake in Estes or Dihedral Route on Duncans Ridge.
Also, this route really sucks I wouldn't give it a single star. It's off width, easily sucks your leg up to the knee forcing you in and out of the crack for each move. Its just a grunt. I bashed the s%^t out of my elbow on the dihedralish face to the right.
Don't bother with this route. The bolted routes here are much more enjoyable.
By John Layko Torkleson
Jun 17, 2012
"Also, this route really sucks I wouldn't give it a single star. It's offwidth, easily sucks your leg up to the knee, forcing you in and out of the crack for each move. It's just a grunt. I bashed the s%^t out of my elbow on the dihedralish face to the right."
I feel like this quote sums up offwidth climbing pretty well. For what it's worth, I'm heading back to lead it next time I'm in the Vrain. It looks pretty dope.
By Dankasaurus
From: Lyons, CO
Oct 19, 2012
|This is a fine and easy lead, a good intro to fist jamming (or perhaps cupped hands?), with great gear. Good small gear can be found on the right wall for the last 1/3 of the route. Bring at least 1 #4 for sure.
By Eric Klammer
From: Boulder, CO
May 12, 2013
rating: 5.6 4c 14 V 12 S 4b
|Fun little route! Once you're past the steeper start, it's a cruise to the anchors. No more than 5.6.
By jamandbees
From: Boulder, Colorado
Jun 2, 2014
rating: 5.7 5a 15 V+ 13 MVS 4b
|Comparing this to the 5.6 slab climb "Community Service", the first move is definitely a little stiffer getting into the climb. The rest is a cruise, plausibly a 5.6 with the one or two 5.7 moves getting into this thing.


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CHICO -- Hearing from locally grown entrepreneurs will be part of eWeek at Chico State University. All events will be on campus and are free.
At 7 p.m. April 15 in Holt Room 170, Collen Winter, co-owner of Lulu's, will speak. The Chico-based retailer and website www. lulus.com specializes in young women's apparel, shoes and accessories.
Lulu's was ranked No. 480 on the Inc. 5,000 top businesses list in 2012, and the fashions it distributes have been featured in various magazines, including Seventeen, Instyle, Cosmo and others. Over a recent three-year period, Lulu's growth was pegged at 803 percent, according to the company.
Winter owns the business with her mother, Debra Cannon of Chico.
At 7 p.m. April 16 in Ayers 201, the movie "The Social Network" will be shown. MovieWeb says: "The Social Network explores the moment at which Facebook, the most revolutionary social phenomena of the new century, was invented — through the warring perspectives of the super-smart young men who each claimed to be there at its inception."
At 7 p.m. April 17 in Ayers 120, Matt York of Chico, founder of Videomaker magazine and a Chico State instructor, will talk about social entrepreneurship. York is behind a social entrepreneurial venture called One Media Player per Teacher. The venture provides video technology and training to charities working in the poorest places in the world.
At 7 p.m. April 18 in Ayers 120, Andrew Gazdecki, founder and CEO of Bizness Apps, will talk about "Technology and the Entrepreneur."
Bizness Apps is one of the nation's leading suppliers of mobile apps for small businesses.
In the two years since Gazdecki graduated from Chico State, he has built his business up to more than $6 million in annual sales. Now a Bay Area resident, he is also a past winner of the Chico State business concept competition.
From 5 to 8 p.m. April 19 at Selvester's Cafe, the Business Concept Competition Finals and Pitch Party is scheduled.
Ten finalists will be competing for $1,000, with PowerPoint and "speed pitching" to more than 40 judges who are entrepreneurs, domain experts or industry professionals.
Judges and the audience will participate in determining the winners.


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I am pleased to announce I am working on a new EP with Radical G. You can hear a clip of the first song we are working on called Here Comes the Storm above. Glenn is from Belgium so he has Electronic Body Music rhythms in his blood. I think we will have another two songs finished by August and soon after we will take the stage together here and there. I expect this EP to be a big one.
"Dark electronic madness founded in 2002 by Glenn Keteleer with pounding Rave sounds and techno hooks. No excuses regarding styles, Gloomy atmosphere's, Wave & Elektro infuences by legendary bands as TNJ and Front 242 are part of the game… There's no denial the Belgians have a fond taste for the darker side of the spectrum."
For more info: radicalg.com


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Mauer getting extra work in with new pitchers
FORT MYERS, Fla. -- The first three pitchers in the Twins' rotation -- Vance Worley (Phillies), Kevin Correia (Pirates) and Mike Pelfrey (Mets) -- are new to the organization this season. That alone would have meant a steep learning curve for All-Star catcher Joe Mauer. Throw in the fact that played for Team USA in the World Baseball Classic and the degree of difficulty only increases.
Terry Ryan isn't worried.
"We've had a lot of pitchers come and go over the last several years. He's had a lot of opportunity to get used to the change," the general manager said before Thursday night's 6-1 loss to the Red Sox at Jet Blue Park. "He had to get used to the WBC pitchers this last month. So I don't think it takes him all that long. He certainly has been around long enough. A couple times through the lineup or a couple times through their starts, I'm sure he's somewhat acclimated now."
Just to be sure, Mauer is getting in all the work he can with the new guys. He caught Worley on Wednesday. He caught Correia on Thursday night. And he'll catch Pelfrey when the Twins wrap up Grapefruit League play on Saturday.
"He's trying to get as familiar with those guys as he can. And he's pretty adept at knowing what he's trying to accomplish with these guys," Ryan said.
Mauer had a double, one of Minnesota's five hits against Boston. He's batting .448 for the spring. Ryan is encouraged not only by how well he's performed, but at how much work the catcher's getting behind the plate. Last season, coming off knee problems, Mauer started 144 games, but 42 were at designated hitter and 30 were at first base.
"I think he's probably as prepared to go into the season as he's been in a number of years," the general manager said. "He's healthy. He's been out there quite a bit and it's been behind the plate for the most part. It's not been at first or any of that stuff. I think he's well prepared. He looks good. He's swinging the bat well. I think he feels comfortable behind the plate. So I suspect he's ready to go. He's probably itching to go."
Paul Hagen is a reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.


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A SNEAK thief has stolen more than £6,000 in cash from a sheltered housing complex in Malvern.
Police are now appealing for witnesses to the theft which took place sometime between 12.30pm and 3pm on Thursday, May 15 at a flat in Geraldine Court, Geraldine Road.
Detective Constable Thomas Birchley said: "We are appealing to anyone who saw any suspicious behaviour in the Geraldine Road area last Thursday and particularly anyone carrying a bag.
"We also want to hear from anyone who knows of a person with an unusually large amount of extra cash."
Anyone with information is asked to contact DC Birchley on 101 quoting incident number 623s 150514.


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(Rustic pasta Sauce with Italian Sausage, Zucchini, and Sage was updated with better photos and step-by-step instructions, September 2014.)
Rustic Pasta Sauce with Italian Sausage, Zucchini, and Sage
(Makes 4-6 servings, recipe created by Kalyn)
5 links (19.5 ounces) hot or mild turkey Italian Sausage
2-3 T olive oil (depending on your pan)
1 large sweet onion, chopped
2 T minced garlic
2-3 medium zucchini or yellow squash (about 4 cups squash cut into pieces about 1/2 inch wide)
1 tsp. Italian herb blend
1/2 cup finely chopped sage (about 20-30 sage leaves, washed and finely chopped)
5 ounces dried Penne, Rotini, or other pasta shape of your choice
salt for pasta cooking water (about 2 tsp.)
1/2 cup + 1/2 cup pasta cooking water
salt and fresh-ground pepper to taste
fresh grated Parmesan cheese for serving if desired
Heat 1 T olive oil in large dutch oven type pan with high sides, crumble in Italian sausage, and cook over medium-high heat until well browned, breaking apart with turner as it cooks. This may take 10-15 minutes or more. (As soon as the water boils, add pasta, stir, and cook until al dente according to directions on your pasta package.)
When the sausage is done, remove from the pan and set aside. In the same pan, heat 1 T olive oil, add onions, and cook over medium-high heat about 4-5 minutes or until onions are starting to brown. Add garlic and Italian Herb Blend and cook 1-2 minutes, then add more oil if needed and add cut squash. Saute squash about 8 minutes or until it's tender and starting to brown. Then add the sausage, sage, and 1/2 cup pasta cooking water and cook 2-3 minutes more.
Drain pasta as soon as it's al dente, saving another 1/2 cup cooking water. Add the cooked pasta to the pan (with the additional water if it seems needed.) Cook 1-2 minutes more, season to taste with salt and fresh-ground black pepper and serve hot, with freshly grated Parmesan cheese to add at the table if desired.
South Beach Suggestions:
Nutritional Information?
More Pasta Ideas with Garden Veggies:
(Recipes from other blogs not always South Beach Diet friendly; check ingredients.)
The BEST From Scratch Slow Cooker Pasta Sauce ~ Slow Cooker from Scratch
Grilled Zucchini Mock Lasagna with Italian Sausage, Tomato, and Basil Sauce ~ Kalyn's Kitchen
Orzo with Roasted Vegetables ~ Recipe Girl
Macaroni with Greens, Lemon, and Parmesan ~ Kalyn's Kitchen
Brown Butter Roasted Vegetable Pasta Skillet ~ How Sweet It Is
Vegetarian Penne Pasta with Butternut Squash, Mushrooms, Scallions, and Goat Cheese ~ Kalyn's Kitchen
(Want even more recipes? I find these recipes from other blogs using Food Blog Search.)
Blogger Disclosure:


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Version 1.1 Fixed videos not playing issue.
Your one stop gap for all unlimited feature packed Indian News, Videos, Music, gossips and much more. Stay upto-date and fully informed on news, gossips, latest tweets that matter to you. Terms of Use: India Darshan sources its contents from various newspapers, feeds and we do not produce or. Freeware download of India Darshan 18.104.22.168, size 2.10 Mb.
Spice Hub is one stop for all the Indian Cuisine Recipes. It is the compilation of all the YouTube videos, segregated by different parts of Indian food and recipes. This app gives almost all the Indian recipes videos available in the market. Cook the most delicious and tasty food of the world and Enjoy. Eat Tasty, Stay Healthy!!. Freeware download of Spice Hub 22.214.171.124, size 2.10 Mb.
Vahrehvah is your ultimate Indian Food and Recipe Cooking channel offering Cooking Videos,Tips,Recipe Reviews and mouth watering Free Indian food videos with detailed steps of Cooking Instructions in Authentic Indian style. Vahchef Inspires you to Cook with Perfect ingredients to rekindle your senses, learn the art of impressing your loved ones and. Freeware download of VahRehVah Recipes 18.104.22.168, size 1.05 Mb.
Do you enjoy Indian food at friends' place or in restaurants? Did you always want to try to cook for yourself or friends and do not know where to find different recipes? Or if you want to cook something random, something you did not know to cook?
This app categorizes Indian recipes videos into tiffins (breakfasts), veg, non-veg, snacks and. Freeware download of Indian Recipe Videos 184.108.40.206, size 2.10 Mb.
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This app contain a lot of full videos and movies about Indian Movies that newest movies, new movies release and full movies.
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This app also includes latest videos right from the T20 world cup as well as Blog for all the latest news from the ongoing tournament.
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This app contain a lot of full videos and movies about New Indian Movies that newest movies, new movies release and full movies.
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Spice up your vegetarian meals starting NOW! With "Vegetarian Indian Cooking: The Video Guide" – a Vook that blends delicious Indian recipes with how-to videos – you'll learn how to make memorable, easy vegetarian meals any time. Download it now and infuse your diet with some serious flavor! With "Vegetarian Indian. Free download of Vegetarian Indian Cooking: The Video Guide 126.96.36.199, size 149.95 Mb.
Ver-22.214.171.124- Video not playing bug fixed
This app contains videos of Yoga by Swami Ramdev Ji. Yoga is an ancient Indian practice and is an important part of traditional Indian or "Ayurvedic" medicine in India. Yoga uses several exercises including breathing, meditation, and body posture exercises. Many different styles of. Freeware download of Baba Ramdev Yoga 220.127.116.11, size 2.10 Mb.
*** v2.0 Update ***
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Get Shlokas , Pictures and Videos of Shri Mad Bhagwad Geeta - The Great Indian Epic !!. Freeware download of Bhagwad Geeta 18.104.22.168, size 3.15 Mb.
Biz Pathshala is a mobile learning application for ING Life for its executives, contractors and other stakeholders to learn on the move. App will give access to videos from top Indian practitioners provided by Bizpunditz. In addition, this will give access to videos and/or other contents that needs to be pushed for communication purposes to the. Freeware download of Biz Pathshala 188.8.131.52, size 1.05 Mb.
*** This is app based on Indian Hindi TV Show ***
This app provides you all the details for famous Indian comedy TV show Dekh Bhai Dekh. Including details about start cast, it provides easy access to all the videos related to it.
2.0 Added ad support
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Dinesh KArthik , also known as DK is one of the most talented Indian cricketer. this app has list of his videos. Freeware download of Dinesh Karthik Vid 22.214.171.124, size 2.10 Mb.
This is the app which shows some videos related to the popular Indian cuisine dishes and helps you making them.. Freeware download of Ghumaghumalu 18.104.22.168, size 2.10 Mb.


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Shaun of the Dead (2004)
58 mistakes
Directed by: Edgar Wright
Starring: Bill Nighy, Kate Ashfield, Lucy Davis, Nick Frost, Simon Pegg
Visible crew/equipment: At Barbara and Phil's house, just as the hooded zombie bites a chunk out of Phil's neck (before Shaun leaps over the car hood) the black mat with two long white marks is visible on the pavement, behind the second zombie (beside the car). It's gone in following shots.
Visible crew/equipment: In the Jaguar, after Ed explains that he already adjusted the seat and Shaun shouts, "Careful!," when Ed pulls out of the driveway a seated crewmember is reflected on the side of the car. This does not refer to the zombie extras.
Visible crew/equipment: When the blue tux zombie walks in through the ever unlocked front door, in the shot facing Ed and Shaun as they get up screaming, two blue tape T-marks are visible on the rug, between the couch and chair. It is visible in a couple of shots, but gone in the rest.
Visible crew/equipment: When Shaun scales up the side of the building to Liz's apartment the second time, just as he places the cricket mallet on the floor and begins to climb through the window, the steel tubing for the scaffold platform is visible just to his right.
Continuity mistake: When Ed drives Phil's Jaguar, its rearview mirror disappears and reappears repeatedly.
Revealing mistake: In the beginning of the movie, where it shows the group of nodding zombies and the Shaun of The Dead logo is on the ground, look to your left, the zombie actor stops nodding and looks around him to see if the shot is still being filmed, and he immediately goes back to nodding. Look out for it, it's obvious.
Continuity mistake: When Shaun bursts into the shed, the whole door falls off the frame. Seconds later when we see the shot of Shaun and Ed with the bat and shovel, there's two pieces of wood attached to the hinge on the right side of the doorframe.
Continuity mistake: When Shaun goes to the newsagents after the dead rise, he gets a drink out of the fridge, which has blood-stained hand prints on. He slips on what we assume is blood as he walks away, yet on the way in and as he leaves the shop you can see behind him that there is no blood or any other liquid on the floor.
Continuity mistake: After Ed and Shaun make the plan to save everyone, we see the close-up shot of the TV where the announcer is saying that nobody should try and save their friends and family. If you look at Shaun, you see the handle end of the cricket bat in his right hand, and he is facing the TV screen. In the shots immediately before and after that, Shaun is not only turned away from the TV, but the handle is in his left hand.
Continuity mistake: At John's pub, when Liz has a look at Barbara's bloody wound, it is about 2" above her left wrist, but when Shaun lifts his mum's sleeve, it's about 6" above her left wrist.
Continuity mistake: When Ed and Shaun use Pete's car, the rearview mirror changes its characteristics between shots. Things such as being large with perfect 90° angles to being smaller and having curvier edges or being attached to the black unit on the car ceiling to being attached to the windshield.
Revealing mistake: When Shaun tackles the blue robe zombie they both slam through the wood fence. The thick black protective vest that Shaun wears is very noticeable under his shirt and is actually visible below his shirt collar.
Continuity mistake: In the pub scene towards the end when the zombies are taking over, Ed lights up a cocktail, but then in the next shot when zombies break through the door and attack him, the rag is unlit.
Continuity mistake: The field in front of Liz's flat is large and unfenced. Yet, when Shaun climbs up to her window, there is a fence not more than ten feet away. He couldn't have run round the side as the sound of the zombies are coming from the same direction.
Continuity mistake: As David is trying all the switches on the fuse box, he flicks a few off and you can see about a half of dozen of them flicked up. In the following shot only one switch is flicked up.
Continuity mistake: If you look closely as Shaun and the gang impersonate zombies, all the zombies around them are constantly moving between shots.
Continuity mistake: When throwing records at the zombies, watch when Ed throws one at the girl. As he throws it, her head is to the left but when the camera shows a close up when the record hits her, her head is to the RIGHT.
Revealing mistake: When Ed hits the zombie in the eye with the record, you can see for a split second that the record misses the zombie completely, then the camera cuts and a different, breakaway (or CGI) record hits the zombie.
Visible crew/equipment: Each time Shaun goes to the store, you can see the reflection of the camera on the freezer's door.
Continuity mistake: When Shaun and Ed repeatedly hit the two zombies in the back garden, no blood appears on the cricket bat or shovel, however it does splatter onto their shirts.


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'"We all kind of have to elevate our game here toward the last stretch of the season," Pominville said. "I think that's how you want to go into it entering the playoffs. In the past I've had some OK starts and pretty good finishes. It's just one of those years where I keep elevating my game."'
You are here: Home / SabresBeat / Sabres' Pominville heats up as season nears end


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DUBLIN — The California Highway Patrol has reopened State Route 84 to traffic following a two-vehicle crash involving a big rig that jackknifed, police said.
Officers were called just before 8 a.m. to the wreck involving an 18-wheeler and a small car at the intersection of the highway and Kilkare Road in Dublin, said officer James Evans.
No injuries were reported.
Officers shut down the roadway at 8:16 a.m. and reopened it to traffic at 9:27 a.m., Evans said.
Contact Natalie Neysa Alund at 510-293-2469. Follow her at Twitter.com/natatliealund.


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Swiss Federal Councillor Ms. Simonetta Sommaruga Recognizes UNDP Support to the Local Communities Hosting Syrian RefugeesJul 13, 2014
H.E. Swiss Federal Councillor Ms. Simonetta Sommaruga, Head of the Federal Department of Justice and Police was accompanied by the United Nations Resident Coordinator Mr. Edward Kollen and a high level delegation from Swiss government, Jordanian government and UNDP to a field visit to witness on-site activities in Mafraq governorate.
Activities are part of the UNDP project; "Mitigating the Impact of the Syrian Refugee Crisis on the vulnerable Jordanian Host Communities" partly funded by the Swiss Agency for Development and Cooperation (SDC).
On her visit to the Municipality of Za'atari and Al Sarhan, the Federal Councillor met with Mr. Abdul Karim El-Khaldi Mayor of Za'atari who briefed her on the pre-existing situation of the municipality and the challenges following the crisis, Ms. Sommaruga also visited Za'atari Park, where Jordanian and Syrian community worked on the beautification and improvement of the facilities, as part of the Project's Community Outreach activity under the support of the World bank Emergency Services & Social Resilience Project (ESSRP).
The tour also included visit to a satellite vocational workshop in Sarhan Municipality where group of female youth beneficiaries from the local community have been trained on sewing and assembly lines and employed through the support of UNDP vocational programme funded by SDC and targeting around 500 vulnerable unemployed youth from Irbid and Mafraq.
The delegation concluded their visit at one of the recently established micro-businesses for a beneficiary who went through a Business Planning training aims at enhancing entrepreneurial skills of 300 unemployed youth in the hosting communities .Both livelihood activities provide youth with the required skills to become economically active, with the hope that the labour market presently challenged by the Syrian crisis will grow in the future and employ more peopleContact information
Khuzaima Jaber, Communications Officer firstname.lastname@example.com


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Tech Beat: Moving day - Tips for setting up a new computer
Click here to subscribe to Law Officer Magazine
The recent phenomenal growth and evolution of technology has impacted law enforcement as heavily as the rest of society. While many agencies have access to specialists who can help implement new computers and similar technology, many others do not. These departments often rely on the expertise of an officer or other department member. Additionally, individual officers and other personnel sometimes struggle with their own technical support issues as they try to set up increasingly complicated computer equipment in their homes. For those departments and officers facing this dilemma, this month's column will help you get your new computer up and running.
Those of us who have fooled around with computers for any length of time have faced the pleasurable problem of acquiring a new machine and setting it up. This not only involves getting the operating system (OS) fine-tuned to our liking and installing all of our applications and programs, but also getting our data files and settings transferred to our new pride and joy. This can seem like an insurmountable task, but it need not be.
Keep in mind that over the course of time, most computer users install and uninstall different programs, fool around with their settings, surf the Internet frequently, and generally do many other things that can leave a machine huffing and puffing under the burden of leftover "orphaned" files, improper settings and programs it no longer needs. In fact, most of us experience little anomalies from time to time; error messages can pop up without explanation, and we haven't the slightest idea what to do. So, this process of moving out of an old machine and into a new one is really an opportunity for a fresh start.
The New Machine
Usually, the first time you turn on a new computer, it will go through a lengthy start-up routine prescribed by the manufacturer. During this initial start-up, the OS (usually Microsoft Windows, but not always) finishes settling in by asking you to enter such information as your time zone and the method by which you connect to the Internet. Typically, software registration and activation takes place here, as well.
Once the machine is up and running, the new owner is almost always faced with a screen full of desktop icons for pre-installed software, much of which they don't need or want. Experienced users will head for the Add/Remove Programs utility in the Control Panel. New or novice users should wait until they get familiar with the new machine before deciding what to delete and what to keep. This is especially true if the new computer is a different brand than the previous machine. Many manufacturers install proprietary programs, some of which are necessary for the proper operation of such things as sound cards and keyboards. Your new computer's operating system will start out in its most generic mode, and over time you'll fine-tune and tweak it to your liking. Windows has literally hundreds of settings you can adjust, and only a few of them are readily apparent to the casual user. As you become more familiar with your machine, you'll want to make adjustments. To do this safely, consider using a "tweaking" utility. Two of the most common are Microsoft Powertoys for XP, and Tweak-XP by TotalIdea Software. The first is free, and the second will run you about $40.
Powertoys is a collection of different add-on programs that can prove pretty handy, and although they come from Microsoft, they aren't actually considered part of Windows, so Microsoft Tech Support doesn't support them. Tweak-XP is an extremely powerful program that enables you to make many adjustments to your Windows installation. While most of the tweaks are safe, it's possible to mess things up by going too far with Tweak-XP, so it's probably better left to more experienced users.
For now, let's assume that you're going to stick with the basic adjustments that a standard Windows installation allows.
A Couple Considerations
Before you start adding programs and data files to your new machine, there are a couple things that you can do or decide that will make your future computing life easier.
First, if you have a computer with two hard drives, decide now to install all of your programs on your C drive (typically your boot drive, where Windows is installed) and to place all of your data files on your secondary drive (usually designated as the D drive). If you have a machine with only one hard drive, such as a laptop, seriously consider dividing it into two partitions. Without getting too technical, this creates a secondary, or virtual, drive that resides on your main drive. While this used to be a little dicey, software now exists that makes partitioning safe and easy. (In my opinion, one of the best is Symantec's Partition Magic.) Once you've partitioned your drive, it will appear to you as though your computer contains two hard drives. Then proceed with the installation scheme as outlined above.
If you go this route, when you need to do any disk maintenance in the future, such as defragmentation or error checking, you'll only be working with a portion of your drive, and your maintenance tasks will take much less time. Backing up your data will be easier, too. If you're working with a computer that has two actual drives, keeping your data on one and Windows on the other will also help your computer run faster.
Second, decide to set up a directory structure that facilitates easy data management and backup. By default, Windows and Microsoft Office (as well as many other programs) want to save your data files to the My Documents folder in Windows. The problem is the My Documents folder resides on your C drive as part of Windows. It might make it a little easier to navigate to your files if you allow this, but eventually your C drive will bloat with all of your data, which you should be placing on your D drive anyway. Many other programs create their own data directories within their own program folder. This has two negative effects: first, it again places your data on the C drive, and second, your data files will be scattered all over your drive, in many different folders, making it very difficult to effectively back up your files.
To alleviate these problems, create a master directory on your D drive, and within this master create subdirectories for each program. Then, as you install your software, you can go into each program's "Options" dialog and point the "Save" function to your newly created subdirectory.
When it's time to back up your files, or to find a file, you can easily go to the right place without having to search your entire list of files.
Moving Your Data
Now you've got your applications installed, and it's time to get your data onto the new machine. If you don't have a lot of files, this is pretty simple: Copy the files to a CD or USB drive; then copy them from that device into your newly created directories on the new machine.
If you've got a lot of data, it's a little more complicated. If you're on a network, you can usually transfer the files across the network to the new machine. If not, you will have to link the machines another way.
There are a number of software solutions to help you do this. With most, you install a piece of software onto the host (or old) machine, then connect the two machines together with a special cable (called a crossover, or bridge, cable). The same software will also allow you to transfer files over a network, or by putting them onto removable media, like CDs.
Many of these migration software products promise to relocate your applications, and even your settings, to the new machine as well. While most work well transferring settings, they leave a lot to be desired in the applications-transfer department. In my experience, I've found it's usually better to just reinstall the applications on the new machine. That way you avoid any problems caused by the transfer process, and you get a clean install (we're after a fresh start, remember?).
One of the most highly rated products of this type is PC Relocator by Alohabob Software. Expect to pay about $70 (it comes with the USB cable that you need for the transfer).
Things to Remember
There are a couple of things many folks forget during this process, and if you clean off your old machine and sell or recycle it, you'll be sorry if you do.
First, if you use Microsoft Outlook, Outlook Express or some other POP3 e-mail client (meaning that your e-mail program actually downloads your messages to your computer, removing them from the e-mail server), you need to get the old messages onto the new machine. In Outlook, your messages, along with your calendar and contacts, are in a file with the extension .pst, probably named "personal folders.pst." Microsoft has posted instructions online for moving your Outlook data here: http://office. microsoft.com
In Outlook Express, the process is a little more complicated, but not difficult. You can find instructions for moving your Outlook Express data here: http://support.microsoft.com.
If you use an AOL, Yahoo or Hotmail account for e-mail, this isn't an issue because these IMAP e-mail services keep your messages on the server, and you go there to look at them. Usually your e-mail address book stays online, too.
You'll also want to move your Internet browser's Favorites folder so you don't lose all of your saved Internet links. The procedure for this depends on which browser program you use, so check out your browser's Web site for directions.
As a side note, if you do start using Tweak-XP, it allows you to change where Windows looks for many of its system directories, which is a big help. And, of course, most migration software will move these directories for you, although the process might prove unreliable with some software packages.
If All Else Fails
If you're new to computing, or just nervous about this whole process, many computer repair shops will make the transfer for you-for a fee. Those of us who take pleasure in driving ourselves crazy and have a lot of time on our hands would rather save the money and mess things up ourselves. Whatever you decide, once you get things switched over, you're in for a treat. Aside from the fun of having a new computer to play with, you'll experience the enjoyment of a clean-running machine, all tuned up and ready to go. If you've been getting frustrated with your old machine, sit back and enjoy.
Steve Ashley is a retired police officer, and an active trainer and risk manager. Contact him at email@example.com.
Request product info from top Police Mobile Computers companies
Thank You!


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Red-hot Ozuna cleans up; McGehee down to fifth
ANAHEIM -- There is no disputing the impact Casey McGehee has made on the Marlins' lineup. The veteran has offered a professional approach, driving in huge runs all season and providing protection in the cleanup spot behind Giancarlo Stanton.
But since the All-Star break, McGehee had driven in just eight runs entering Monday, including two in August.
With McGehee hitting .247 in August, manager Mike Redmond opted to make a change with his No. 4 hitter. Marcell Ozuna entered on a nine-game tear, batting .405 with three homers, four doubles and 11 RBIs. So in the series opener on Monday at Anaheim Stadium, Ozuna was moved to the cleanup spot for the first time all season. McGehee, who hit fourth in 114 games, was dropped to fifth.
Ozuna drove in a run with a sacrifice fly and McGehee plated a run with a single in Miami's 7-1 series-opening victory.
"You always think about that, are you giving the guy [Ozuna] too much?" Redmond said before the game. "But at the end of the day, the numbers are the numbers. He's hitting and he's driving in runs. Hopefully he continues that. We've got nothing to lose. We're trying to win ballgames and score runs."
After dropping two of three at Colorado, the Marlins' playoff hopes took a hit. There is a sense of urgency to get more production.
Ozuna entered Monday second to Stanton on the team in homers (19) and RBIs (70).
"When he's going good, you want him up to the plate with the most guys on base," Redmond said. "He's been hitting. He's been driving in runs and getting big hits. It seems like a perfect time to get our hottest hitter hitting behind 'G.'
"We've had a tough time driving in those runs. We need to drive runs in to win those ballgames."
Ozuna, 23, has been used up and down Miami's lineup. Before Monday, the only spots he didn't hit was leadoff and cleanup. But in the Minor Leagues, he had experience cleaning up. As a rookie last year, he appeared in 41 games in the No. 4 spot. He batted .255 with no homers and 13 RBIs.
Having Stanton hitting third and Ozuna fourth could be a preview of next season's middle of the order.
McGehee, who has one more season left in arbitration, is expected to return to Miami next year.
The 31-year-old has enjoyed a strong season, batting .295 with 62 RBIs.
"Guys go through spurts or funks, and he's probably in a little bit of that right now," Redmond said. "But at the end of the day, the guy has done a great job for us. He's had a ton of big hits for us."
Joe Frisaro is a reporter for MLB.com. He writes a blog, called The Fish Pond. Follow him on Twitter


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Hot Toys gets some competition: New 1:6 Spidey swings into action...
Hot Toys recently announced plans for a 1:6th scale Amazing Spider-Man figure based on the new movie (see HERE) and now Medicom of Japan looks to be doing the same. Presenting the Real Action Hero (RAH) Amazing Spider-Man. The figure will feature a slew of alternative hands, figure base (not pictured) and a textured outfit that replicates Spidey's new suit. The RAH Amazing Spider-Man will be limited to only 1500 pieces and is scheduled to arrive in Japan this August. No release date on the Hot Toys version yet, so if you're a fan itching to get your hands on a high-end 12-inch figure of the new Spider-Man first, this would be the one.
Source: medicomtoy.co.jp
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To buy action figures, take a look at BigBadToyStore.com, RedfordFilms.com, Toynk.com, PastGenerationToys.com, BriansToys.com, ToyWiz.com, and MonkeyDepot.com.


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I was just thinking that this site would be nice if it had an intro page or a main page that introduces the Dhamma of the Buddha. It can include links like Introduction to Theravada, the Life of the Buddha, His teaching (4 Noble Truths). FAQ (which covers rebirth, anatta, Dependent Origination etc) link, Meditation link, and link to the whole Tipitaka. And of course there will be a forum link that brings everyone here to discuss the Dhamma.
Just a thought that I might as well throw it out there.


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AJ has been typecast.
Ryan Wells:
- Former JBW TV Champion
- Former EWNCW Evolution Champion
- Former Undisputed BWA Grand Champion
(w/ Gillz)
Xavier Hightower:
- Former RTE Tag Team Champion
(w/ Kaige Chamberlain)
''Ricardo Rodriguez is the best character on WWE TV.''
To hell with insincerity. Fuck you!
Former IWA Revolution Creative Team
Former IWA/WWE
Last Ever IWA Vanities Champion: Juno Mercury
2013: Women's Wrestler of the Year,Juno Mercury (IWA)
2013: Vanity of the Year,Juno Mercury (IWA)
PWR Women's Champion: Juno Mercury
I get that Big E Langston dropped the NXT CHAMPIONSHIP
but....to Bo Dallas out of all people? WTF!