text:
Assessment of Normal Value of Acoustic Radiation Force Impulse (ARFI) Elastography in HIV Patients
The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified February 2012 by Yonsei University.
Recruitment status was: Recruiting
Recruitment status was: Recruiting
Yonsei University
Severance Hospital
Information provided by (Responsible Party):
Yonsei University
ClinicalTrials.gov Identifier:
First received: January 21, 2011
Last updated: February 1, 2012
Last verified: February 2012
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Detailed Description:
This is a prospective cohort single center study for assessment of normal value of acoustic radiation force impulse elastography and fibroscan in HIV patients without abnormal liver function and chronic liver disease.
|HIV Infection
|Device: Acoustic radiation force impulse imaging
|Study Type:
|Study Design:
|Observational Model: Cohort
Time Perspective: Prospective
|Official Title:
|Prospective Study for Assessment of Normal Value of Acoustic Radiation Force Impulse (ARFI) Elastography in HIV Patients Without Abnormal Liver Function and Chronic Liver Disease
Resource links provided by NLM:
MedlinePlus related topics: Diagnostic Imaging HIV/AIDS Liver DiseasesU.S. FDA Resources
Further study details as provided by Yonsei University:
Primary Outcome Measures:
- Evaluation of ARFI velocity in HIV patients [ Time Frame: 2 years ]Measurement of ARFI velocity is non-invsive ultrasonographic technique. It is performed with a abdominal convex probe which is same probe as conventional ultrasonography. Short-duration acoustic radiation forces result in shear-wave propagation away from the region of excitation and are tracked using ultrasonic correlation-based methods. This results are called ARFI velocity which is expressed as meters per second
|Estimated Enrollment:
|Study Start Date:
|October 2010
|Estimated Study Completion Date:
|June 2012
|Estimated Primary Completion Date:
|June 2012 (Final data collection date for primary outcome measure)
|Assigned Interventions
HIV patients with normal liver status
HIV patients without abnormal liver function and chronic liver disease
Device: Acoustic radiation force impulse imaging
Acoustic radiation force impulse (ARFI) imaging were measured 10 times in each patient.The region of interest was chosen in an area where the normal liver parenchyma was at least 6 cm thick and free of large blood vessels was chosen. A measurement depth of 2 cm below the liver capsule was chosen to standardize the examination.
Other Name: ARFI imaging
Detailed Description:
HIV positive patients who have liver dysfunction have shown to be correlated with high mortality and morbidity. To date, ARFI elastography has been known to correlate with the degree of liver fibrosis in chronic liver disease. However, ARFI velocity has not yet been reported in HIV patients. The aim of this study was to identify the normal range of ARFI velocity and liver stiffness value by recruiting HIV patients without abnormal liver function and chronic liver disease.
|Ages Eligible for Study:
|20 Years to 80 Years (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
|Sampling Method:
|Probability Sample
Study Population
HIV patients without abnormal liver function and chronic liver disease
Inclusion Criteria:
- Age > 20 years
- HIV positive patients
- The patients who is willing and able to provide written informed consent to participate in this study
Exclusion Criteria:
- Co-infected with HIV and HBV or HCV
- History of any other forms of liver disease
- Any gross abnormality on the imaging finding including MRI and CT
- Any laboratory abnormalities regarding liver condition (Platelet count < 150 x 103/ul, Fasting glucose > 110 mg/dl, AST > 40 IU/L, ALT> 40 IU/L, Albumin < 3.3 g/dl, Total bilirubin > 1.2 mg/dl, GGT> 54 IU/L, ALP > 115 IU/L , Ferritin > 322 ng/ml)
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01283243
Please refer to this study by its ClinicalTrials.gov identifier: NCT01283243
|Contact: Seung Up Kim, MD
|Contact: Kwang-Hyub Han, MD
|Korea, Republic of
|Severance Hospital
|Seoul, Korea, Republic of, 120-752
|Contact: Seung Up Kim, MD +82-2-2228-2108 firstname.lastname@example.com
|Contact: Kwang-Hyub Han, MD +82-2-2228-1949 email@example.com
|Sub-Investigator: Chang Young Son, MD
Sponsors and Collaborators
Yonsei University
Severance Hospital
|Study Chair:
|Kwang-Hyub Han, MD
|Yonsei University Colleage of Medicine
|Principal Investigator:
|Seung Up Kim, MD
|Yonsei University Colleage of Medicine
More Information
Keywords provided by Yonsei University:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on September 21, 2017
|Responsible Party:
|Yonsei University
|ClinicalTrials.gov Identifier:
|NCT01283243 History of Changes
|Other Study ID Numbers:
|Study First Received:
|January 21, 2011
|Last Updated:
|February 1, 2012
Keywords provided by Yonsei University:
ARFI Imaging
Normal values
HIV infection
Additional relevant MeSH terms:
HIV Infections
Lentivirus Infections
Retroviridae Infections
RNA Virus Infections
Virus Diseases
Sexually Transmitted Diseases, Viral
Sexually Transmitted Diseases
Immunologic Deficiency Syndromes
Immune System Diseases
ClinicalTrials.gov processed this record on September 21, 2017


text:
Government spending programmes brought forward in a bid to beat the recession will provide employment for at least 100,000 people in the current difficult economic times, Gordon Brown says.
The Prime Minister promised to "invest through this downturn" to support jobs and create a greener and more technologically advanced Britain.
In a pre-Christmas interview with the Daily Mirror, Mr Brown promised help for people losing their jobs in the downturn to find new work.
He has made the fight against unemployment his top priority for 2009, the paper reported.
Mr Brown said that his response to the economic crisis had been guided by his conversations with voters and businesses at weekly meetings organised around the country, where he has heard concerns about employment, access to credit and meeting bills.
He said that the Government's decision to bring forward £10 billion worth of infrastructure projects would help support jobs in the coming two years.
"School building repairs and school building alone will employ about 100,000," Mr Brown told the paper.
"It is possible when you do these programmes for it to take months. But the ones we've got earmarked are ones which can take place now"
Other projects to be announced in the New Year include plans to make high-speed broadband internet available nationwide through huge investment in a fibre-optic cable network.

subset: commoncrawl


text:
Kenneth A. Haukom passed away peacefully in Los Altos on November 7, 2013. He and his family and many friends celebrated his 100th birthday in July.
Born July 18, 1913, in Conrad, Montana, Ken was the third child of Edward and Clara Haukom. The family including sister, Evelyn, and brother, Jack, had moved to Conrad from their native Minnesota to homestead the land. Later the family ran the Conrad Mercantile Company. In 1921, after Ken's mother became ill as a result of the influenza epidemic, the family returned to Hayfield, Minnesota. Following graduation from Hayfield High School in 1931, Ken attended Rochester Jr. College and the University of Minnesota.
Adventure called in 1936, and Ken set out to see the world on a Norwegian tanker. He photographed the coastline of Japan and the images were used by the U.S. War Department as war clouds were forming around the world. Ken returned from his travels and attended the University of California, Berkeley where he graduated in 1939. In 1940 he worked for Bethlehem Steel as an estimator and later became Chief Scheduling and Progress Engineer for Permanente Metals Corporation, which built 420 ships for the U.S. Maritime Commission.
On Christmas Day, 1940, Ken married Beverly, his longtime sweetheart from Minnesota. They settled in the East Bay where they had two children and were very active in the community, schools, and church. In 1997, Beverly passed away. They had been married nearly 57 years.
Ken joined Brown, Pacific, Maxon in 1946, a sub-contractor responsible for building the airport, hospital, roads, and housing on Guam after WWII. In 1956, Ken began working for Magna Engineering in Menlo Park, and he chose to move his young family to Los Altos. One more career move followed in 1958, when he joined Lockheed Missiles and Space in Sunnyvale where he worked for twenty years retiring in 1978.
Ken was a member of Immanuel Lutheran Church, and active at the Los Altos Senior Center, and the Mid-Peninsula Widows and Widowers Association. At "WW" thirteen years ago Ken met Bess Whitaker and over the years Ken and Bess shared faith, family, friends, travel, sports, bridge, dining and dancing.
His advice was always to stay Involved and to keep your focus on Faith, Family, and Friends.
Ken is survived by son, Ken Haukom, Jr. (Vicki), daughter, Karen Reid (Kirk), grandchildren, Chris, Kevin, Kyla, and Kenneth and great-grandchildren, Hannah and Reid.
A memorial service will be held at Immanuel Lutheran Church, 1715 Grant Road, Los Altos on Friday, November 22, 2013, at 2:00 pm.
In lieu of flowers, contributions can be made to the Mission Endowment Fund of Immanuel Lutheran Church of Los Altos, California.


text:
KAREN Lloyd was rarely seen without a steaming hot cup of Costa coffee in hand.
And now her chain of choice is poised to honour its most loyal customer by furthering her charity work in a fundraising day in aid of Prospect Hospice, coinciding with the Adver's 160 Appeal for the Wroughton organisation.
Karen, or Moosie as she was lovingly nicknamed by husband Alan, died at Prospect Hospice on Tuesday, February 4 – six months after being diagnosed with stage three cancer. She was 51.
The latte enthusiast, of Freshbrook, could always be found enjoying a drink at one of the branch's coffee shops. Her infectious laughter and huge personality earned her fast friends among Swindon's Costa baristas.
The mother-of-two's obsession with the cafe led her loved ones to bury her in a custom-made Costa coffin bearing the firm's logo – a quirky move which made headlines as far as America.
To celebrate Karen, baristas will hold a fundraising day, complete with raffles, on Saturday, March 29, at six of Swindon's Costa shops: the Drive Through, Havelock Street, The Outlet, The Station, The Parade and Next@Home.
Matt Burt, manager of the Next@Home branch, said Karen had made such a lasting impact on employees they had all jumped at the chance to pay tribute to her.
"Staff were affected by the fact that she passed away so quickly," he said.
"She was such a lively character. They all said 'let's make sure we do something in her memory and raise money for her favourite charity'. Staff in the town centre shops were especially close to Karen. They are all so keyed up to do the fundraising.
"We are hoping to raise between £500 and £1,000."
In June last year, Karen was diagnosed with invasive breast cancer after a mass half the size of her breast was spotted by specialists at the Great Western Hospital.
Always the optimist, she treated her diagnosis as an opportunity to raise funds for the hospital's breast cancer unit.
On December 12, she discovered the cancer had spread to her spinal fluid and was given between two weeks and two months to live. A week later, she was admitted to Prospect Hospice where she died on February 4.
Her close friend Lynzi Barrett approached Costa in a bid to collect funds for the hospice which cared for Karen in her final moments.
"She would come up with any excuse for a coffee," said Lynzi, 53, of Rodbourne Cheney.
"I decided to contact Costa's head office, who provided flowers and cups for Karen's funeral, to see if they may like to make a donation to the Prospect Hospice. A month later Costa have organised a fundraising day for Prospect in honour of Karen.
"All the staff will be dressed in pink and they will be having raffle prizes donated by many of the Swindon stores. Karen would have been so pleased. She would really want Prospect to benefit. The family are chuffed to bits."
To donate to Prospect Hospice in memory of Karen, visit www.prospect-hospice.net


text:
Boone Street Band
The Boone Street Band is a popular music group made up of the rhythm section and lead players from the Gonzaga Jazz Ensemble: Lead Alto Sax (and Baritone Saxophone), Lead Tenor Sax, Lead Trumpet, Lead Trombone, Piano, Guitar, Bass, and Drums. The Boone Street Band offers jazz ensemble students the opportunity to perform popular music from artists including Earth, Wind and Fire, Stevie Wonder, Kool and the Gang, Tower of Power, Toto, Average White Band, Corinne Bailey Rae, Rob Thomas, Cheryl Lynn, and Blood, Sweat, and Tears.
The Boone Street Band meets during the normal Jazz Ensemble class and performs on and off campus several times throughout each semester. On campus performances in the past have included Gonzaga's 125th Anniversary Celebration, Madonnastock, GEL Weekend, and the President's Christmas party.
Students interested in participating in the Boone Street Band need to audition for Jazz Ensemble with Mr. Fague during the first week of classes in the Fall. Information about these auditions as well as auditions for other groups in the music department will be posted in the main music building. For further information or to schedule an audition/visit, please contact Mr. Fague at (509) 313-6735 or email@example.com
502 E. Boone Avenue
Spokane, WA 99258-0079
Dr. Timothy Westerhaus
Chair, Music Department
Phone: (509) 313-6733
(800) 986-9585, ext. 6733


text:
Be the first to know about new arrivals, events, special offers and more!
Heel height is 1.50 inches.
For a long day on your feet, the Wayne loafer infuses comfort and
support thanks to a removable triple-density footbed and a
slip-resistant rubber outsole.
Full grain leather is a smooth and water-resistant leather that
does not break down in environments with wet, acidic or greasy
To clean, wipe with a damp cloth. To maintain, use Dansko
Leather Cream.
To find out which Dansko Material Care products to use on your shoes, see our Material Care Reference Guide.
The APMA Seal of Acceptance is awarded to products of exceptional quality that promote good foot health,
manufactured with consumer's comfort and safety in mind.


text:
Topic: Going backwards
Good evening,
I'm still new to the group after posting in December about my sisters resection being halted. She is going down hill fast and we don't seem to know why. She was discharged on Monday, hoping that being at home she would start to eat and generally recuperate for chemo. She just didnt pick up at home and Her gp admitted her on Friday. She is in severe sepsis but getting no better. She is till drowsy, confused, not drinking or eating. Because I'm a nurse my sisters husband has asked me to handle dealing with doctors which I am very happy to do but I feel like we are in a nightmare right now and its getting worse.
We're missing something here. I know she cant be cured but 4 weeks ago she was well enough for chemo to be the plan. But She has just got progressively worse since her external drain was reversed on the 30th December. She only finished a 7day course of intravenous antibiotics last Saturday. My sister is in a hospital 300 miles away for me so I am reliant on doctors calling me back. I'm still waiting 10 hours later. Tomorrow I'm ringing her consultant at the main hospital that did her surgery (why the local hospital didn't ring him on Friday is anyone's guess) to put him in the picture and ask that she is transferred. She's sicker now than she ever was after surgery on 17th Dec and I'm beginning to think this is more than an infection in her biliary tree but something more like an abscess. She has right sided pain - she had portal vein embolisation to the right side in November - it's anyone's guess with a ct what's going in there.
I'm sorry to rant - but if anyone has any nuggets of wisdom I'm all ears. Excuse the spelling and grammar - I don't normally do,such a big post on the ipad!
In the stars now . . . .


text:
Where are the local teams in state preseason polls?
Plant is the area's top large school, according to rankings released earlier this week by floridahsfootball.com.
The Panthers were No. 6 in the preseason poll for teams in Class 5A-8A, behind Miami Central, St. Thomas Aquinas, Apopka, Manatee and Tallahassee Godby – Plant's preseason opponent this weekend.
Armwood was No. 12, just ahead of East Lake in the top 20. Other big schools from the area that received votes were Largo, Pasco, Lakewood, Robinson, Jefferson, Hillsborough and Countryside.
In the small schools division, Clearwater Central Catholic was Tampa Bay's top team, at No. 8. Tampa Catholic was 18th, and Miami Washington held the top spot.
Full disclosure: I'm one of the voters in the poll. But no need to harass me, because I ranked every team perfectly, especially yours, and I totally put your team's rival way low.


text:
2013 Laser Boats Power Boat Prices and Values
Manufacturer note(s):
All values include the trailer.
Select Laser Boats Power Boats Models Below
(2017 - 2000)
A brand under Essex Performance Boats, Laser Boats is a California marine business based on the production of speedy bowriders. Laser Boats was established in 2000 releasing the 22-foot Vision powered by stern and jet drive motors. Other models have been added to the Laser Boats line-up including the Apex and Fury. Fiberglass vessel designs produced by Laser Boats feature open bow seating fitted for two passengers at speed.


text:
Nikolay wrote: How does one "concentrate on the present moment" without stopping thoughts? Or maybe I am overthinking it?
As others have suggested it's not really about "stopping" thoughts but allowing them to pass - so there's a sense of letting go. And usually with samatha one is focussing on a particular object like the breath, which makes this easier. Give it time!


text:
EvaluAtion of Predictive Value of Multisite Intracardiac EchoCardiography During Imaging of Structure and funCTION of Left Atrial Appendage in Comparison to Transesophageal Echocardiography (ActionICE)
Recruitment status was: Recruiting
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
This is a 2- component, single center study, witch aims to evaluate the efficacy of multisite intracardiac echocardiography (mICE) imaging of left atrial appendage (LAA) and in detecting thrombus located in LAA as compared to transesophageal echocardiography (TEE). The study group will consist of patients eligible for atrial fibrillation (AF) ablation procedure (Component I) or cardioversion (Component II).
First component will enroll 100 patients; these patients will undergo clinically indicated TEE & cardiac catheterization procedures with ICE(AF ablation). Second component will enroll 15-20 patients with AF or atrial flutter in whom a thrombus in LAA was detected by TEE prior to electrical cardioversion. The ICE probe will be located in multiple positions in the right atrium (RA), coronary sinus (CS), pulmonary artery (PA), right ventricular outflow tract (RVOT) and esophagus. This will enable the investigators to compare sensitivity and specificity of mICE and TEE.
This study will examine two hypotheses in AF patients undergoing invasive cardiac procedures:
Hypothesis 1: That ICE has comparable efficacy to TEE in visualization of LAA from multiple positions (RA,CS,PA,RVOT and esophagus ). This will be evaluated during the component I of the study.
Hypothesis 2: That ICE can identify low risk patients, CHADS Score < 2,0 in whom immediate cardioversion during the procedure is as safe as based on conventional strategy.
|Atrial Fibrillation
|Device: Intra-Cardiac Echocardiography guided atrial fibrillation ablation
|Phase 4
|Study Type:
|Study Design:
|Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: Single (Investigator)
Primary Purpose: Diagnostic
|Official Title:
|EvaluAtion of Predictive Value of Multisite Intracardiac EchoCardiography During Imaging of Structure and funCTION of Left Atrial Appendage in Comparison to Transesophageal Echocardiography
- Predictive value of ICE compared to TEE in visualisation of morphology and thrombus in LAA. [ Time Frame: intraoperative - up to six hours ]Predictive value of ICE compared to TEE in visualization of morphology (area and volume of LAA) and function of LAA (emptying velocity and ejection fraction of LAA) - offline analyses will be conducted. Quality of LAA imaging will be assessed using 5-grade scale, and compared to that obtained by TEE. Grade 0 means unacceptable quality wheras grade 5 means exellent view of LAA. Exclusion of existence of thrombus in LAA by mICE will enable electrical cardioversion of AF during AF ablation procedure. That will by assessed using binary scale - YES or NO.
|Estimated Enrollment:
|Study Start Date:
|June 2011
|Estimated Study Completion Date:
|March 2013
|Estimated Primary Completion Date:
|February 2013 (Final data collection date for primary outcome measure)
Device: Intra-Cardiac Echocardiography guided atrial fibrillation ablation
|Ages Eligible for Study:
|18 Years to 75 Years (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Patients with paroxysmal/persistent AF
- Patients with or without structural Heart Disease.
- Men or Women aged 18 years or older.
- Patients undergoing an invasive catheterization procedure including right heart catheterization.
- Patients who give an informed consent for participation in the study.
- Patients who have undergone a trans-esophageal echocardiogram within the last 48 hours. Patient witch CHADS2 score > 2
Exclusion Criteria:
- Patients in whom placement of an ICE catheter for adequate atrial visualization is technically not feasible (Right atrium or Esophagus).
- Women of child bearing potential, in whom pregnancy cannot be excluded.
- Patients with any medical condition or social circumstance, which in the opinion of the investigator, would make the patient's successful completion of the study doubtful
Please refer to this study by its ClinicalTrials.gov identifier: NCT01371279
|Contact: Piotr Kulakowski, Prof.
|Contact: Sebastian M Stec, PhD
|Department of Cardiology, Postgraduate Medical School, Grochowski Hospital, Grenadierow 51/59
|Warsaw, Poland, 04 073
|Contact: Sebastian M Stec, PhD 0048512221279 email@example.com
|Contact: Jakub Baran, MD 0048697604544 email@example.com
|Sub-Investigator: Jakub Baran, MD
|Principal Investigator: Sebastian M Stec, PhD
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
|Responsible Party:
|Sebastian M.Stec / Jakub Baran, Medical Centre of Postgraduate Education, Poland
|ClinicalTrials.gov Identifier:
|NCT01371279 History of Changes
|Other Study ID Numbers:
|Study First Received:
|May 23, 2011
|Last Updated:
|June 16, 2011
Additional relevant MeSH terms:
Atrial Fibrillation
Arrhythmias, Cardiac
Heart Diseases
Cardiovascular Diseases
Pathologic Processes
ClinicalTrials.gov processed this record on September 21, 2017


text:
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The System Sonogram
Mocking The Draft
Lining Up The Bullpen 9-10-2016
Tim Huwe
Saturday, September 10, 2016
Bullpen Overuse Made Easy 9-20-2017
Creating interest and concern for bullpen overuse is a tricky path. While people grasp that relievers "probably" do better when "not overworked", the term is vague. Even those wishing to get on-board have no numbers to back up the premise. Today's article is intended to streamline the concept of Bullpen Overuse. Way back last year or so, when I began digging into the concept, the most eye-opening player page was Jonathan Papelbon. An "ace closer" for the contemporary "Moneyball Era" of closers,
Pierce Johnson Claimed By Giants 9-2-2017
When calling up Jen-Ho Tseng for his recent start, the Cubs designated Pierce Johnson for assignment. Today, Johnson was claimed by the Giants. Johnson was a Supplemental First-Round Choice in 2012, added as compensation for Aramis Ramirez signing with Milwaukee. The RHP from Missouri State tended to struggle with control, but had been effective in relief in 2017. To make room on the 40 Man roster for Johnson, Brandon Belt was transferred by San Francisco to the 60 Man Disabled List. The Cubs
What Makes A Good Pro Coach? 9-19-2017
Overnight, Arizona Phil included a very helpful list: the players heading to Instructional Ball, which starts soon. Read his article, as usual. He lists the 77 players attending Instructs, including the eight heading to the Mesa Solar Sox roster. Also included are the coaches. Among the questions below his comprehensive piece is a question, wondering why Chris Valaika (pictured) makes sense as an Instructs coach. Valaika, for those unaware, was a rather light-hitting utility/infielder at the
Congrats To Smokies Mick Gillispie 9-18-2017
Tennessee Smokies broadcaster Mick Gillispie, who has helped the last few years with the Cubs in spring training, has been named Minor League Announcer Of The Year. Mick is a joy to listen to. Smokies games with Mick at the mike are worth the time investment. This is a very well-deserved honor. Many people who work with Gillispie often go on to success in other organizations, which is another tell on how well he performs his job. Gillispie also announces college football, especially Alabama
A Possible Off-Season Add 9-17-2017
Shohei Otani. Yu Darvish. When talking about potential off-season additions, the interest tends toward the big name additions. For perfectly good reason. However, since I believe in the "big picture" aspect of MLB, smaller additions can provide positive returns at a lower cost. Today, I look at a reasonable low-cost addition for the Cubs this off-season. My timeline was livid with the signing of Brian Duensing. After all, "Did you see his numbers the previous two seasons?" Players don't
Is Hendricks An Outlier? 9-17-2017
Today's is a rather brief and easy question? Which means it should have a soft and simple answer. Is Kyle Hendricks an outlier? Hendricks was added in the second piece in the trade when the Cubs sent Ryan Dempster to Texas. Christian Villanueva was the primary piece. Because baseball. However, Hendricks had a reputation going back quite a ways as an extreme strike thrower. The Cubs have had a recent history of drafting "extreme strike throwers" to minor league deals, if just to see how far up
On Tseng's First Start 9-15-2017
Yesterday's start by Jen-Ho Tseng likely displayed quite a bit more about you than it did about Tseng's future as a pitcher. My timeline was lit like a Christmas tree of bad-cliches about baseball. "Must-win game" "Wasting a chance at a win." "Pitcher who isn't ready." "Fifth-string catcher." You may have seen some, as well. Peaking around the third inning. Baseball is a 162 game season. In the regular season. Then, the playoffs loom for ten fortunate teams. For many baseball fans, the
A Gem From Phil 9-14-2017
If you don't periodically pop in on Arizona Phil's commentary at The Cub Reporter periodically, you're doing yourself a disservice. Today, he outdid himself talking about Matt Carasiti, and other things. The response in question is at the bottom of the linked page, and talks strategy, technique, and all that cool wonky stuff. I was noting on MLB Trade Rumors today about how much talent the Cubs have lost recently due to injuries and ineffectiveness. Aaron Brooks, Jack Leathersich, and Pierce
Welcome To The Show Jen-Ho Tseng 9-14-2017
In the constant hunt for a starting pitcher, the Cubs turn to 2014 and 2017 Pitching Prospect Of The Year Jen-Ho Tseng tonight. My first public viewing of Tseng was nothing less than revelatory. But, before that, some back-story on Tseng. In the 2013 international signing class, the Cubs hadn't planned to blow through the limit. The slotting limits were new, and the expectation was still that teams would abide by the limits. However, somewhere along the line, the Cubs sensed they had a shot at
az phil
edgar olmos
christian villanueva
john lackey
eddy julio martinez
gleyber torres
jonathan herrera
corey black
jeffrey baez
kenta maeda
zack greinke
james shields
chris archer
ryan williams
trey mcnutt
eddy martinez
jen-ho tseng
pj higgins
taylor davis
adrian morejon
lazarito armenteros


text:
CLEVELAND - A new, $4.5 million rail loop linking the Port of Cleveland with main lines nearby is expected to enable faster, more efficient movement of cargo from the site.
The Plain Dealer reports the rail loop is considered a key new capability for the first major U.S. port that ocean freighters reach while sailing from the St. Lawrence Seaway into the Great Lakes. The railroad cars generally can carry more cargo and take it further than the trucks that typically move smaller loads to local destinations, such as northeast Ohio factories.
The vice president of maritime logistics says the port is trying to sell shippers on the idea that they can drop off cargo in Cleveland to be transported by rail instead of sailing further into the Great Lakes.


text:
Moderators: Timko, Fritz, Solty, Booter, Blake_T, Frank Delicious
VooDoo wrote:Hey Eric,
Thank you for you interest in Voodoo Disc Golf Bags, Here are the answers to your questions, hope this helps out.
How much is it (including shipping)?
With tax and shipping the cost is $92.75
Are they currently in production and for sale?
They are available
What is the frame made out of? And do you have any pics?
The frame is made of plastic and mesh fabric. To see pics click on this
link below.
http://www.facebook.com/album.php?aid=3 ... 4304859464
Will the putter pocket fit two putters?
One putter pocket and mini pocket
How big are the side pockets? I'm curious if I can get a light jacket in them.
The side pockets are big enough for your light jacket no problem, I carry
a thick hooded pullover sweatshirt.
If you have any other question please don't hesitate. I know if you choose
to go with the Mojo bag you will be much happier with the Style and
functionality then with the competitors. Hope to talk to you soon, take
lordbyron001 wrote:So i purchased a mojo bag recently and figured i should post what i think about it so far. Thankfully, i can say that this is a really great bag. It is what i wanted the REVO carolinas to be. First, the picture shown with the water bottle sagging to side pocket seems strange to me as this easily has the deepest side water pocket slots ive seen on a bag yet. As well the side pockets themselves only unzip to halfway down the side so even when open there is still some bag structure. Inside the large side pockets there are really nice phone pockets on one side with a large mesh side pocket underneath those as well as a main compartment and on the other side there is teh same mash side pocket and a large velcro pocket as well as main compartment. Quads hook up as normal. the 2 putters fit comfortably without having to stretch the pocket itself. Actually has a functional mini slot in front. something i faulted the revo for heavily, i found it really annoying. The inner disc compartment comfortably holds 14 discs with a single divider in it and the frame of the bag itself is made of what seems to be a nice rugged plastic covered in a thin padding then covered in mesh. It fits together with copious velcro then sits in the bag snugly but without causing stress points like the revo does, which eventually stretches the top of the bag out and rips little holes in the bottom of the bag. There is no putter rain flap, which some like but im ok with it. All in all this bag has been an extremely worthy purchase and would recommend anyone to get the mojo bag. oh yeah and it is surprisingly compact for how much it holds. it is definitely a bit smaller than a revo carolina
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text:
Barkevious Mingo
LSU defensive end
Born: Oct. 4, 1990
Status: Single
My favorite thing about LSU is: Working toward getting a degree
If I didn't come to school here, I'd be at: Michigan
What's on TV: Anything on TNT: "Law & Order," "Burn Notice," "Supernatural"
What's in my iPod: Lil Wayne, Drake, Rick Ross
What I drive: Black Dodge Charger
Favorite flick: "Immortals"
What I'm reading: My textbooks
Magazine subscription: Car & Driver
Favorite gadget I own: iPad
Bookmarks: Facebook, YouTube, Twitter
Superstitions: I don't put my gloves on until halftime
Worst habit: Biting my nails
Favorite item on my apartment walls: An action shot of me making a tackle in last year's Oregon game.
Would love to trade places for a day with … Coach Les Miles; I'd like to see what it's like to think like him and be him.
My first job: Sophomore year of high school, I worked for a landscaping company.
My favorite meal: Our pregame meal at Lod Cook Hotel: steak, lasagna and the best cookies in the world!
Talent I'd most like to have: Throwing a football
My favorite player to watch in the NFL: Tom Brady
My dream date: Christina Milian
Favorite city to visit: Atlanta
Favorite sports team as a kid: Los Angeles Lakers (still is my favorite team)
My greatest love: Sports
My favorite physical attribute about myself: My speed and quickness
And least: Nothing; I like how I am.
Favorite value in others: A willingness to win and never quit
My hero: My mom
Bucket list: Traveling overseas, and especially climbing an actual mountain.
Motto: "Winning is not a sometime thing, it's an all-the time thing." — Vince Lombardi


text:
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text: Sorry for the wrong attachment. Installing include files under lib breaks modules that use python distutils. Is it recommended that modules that depend on numpy use numpy distutils instead? Thanks. -- sasha On 1/6/06, Alexander Belopolsky <alexander.belopolsky at gmail.com> wrote: > Numpy include files get installed in <python prefix>/lib/pythonX.X/site- > packages/numpy/base/include/numpy instead of <python prefix>/include/ > pythonX.X/numpy. > > The attached patch fixes the problem. Does anyone rely on the current behavior? > > -- sasha > > PS: Using scipy core svn r1847 on a Linux system. > > > -------------- next part -------------- A non-text attachment was scrubbed... Name: numpy-core-setup-patch Type: application/octet-stream Size: 1505 bytes Desc: not available Url : http://projects.scipy.org/pipermail/numpy-discussion/attachments/20060106/fd1febad/attachment-0001.obj


text:
Home Concert Tickets Country and Folk Clannad
Clannad Tickets
Find the Clannad tickets you're looking for on viagogo, the world's largest ticket marketplace. Select an event to view the range of tickets available or view the Clannad tour dates to find an upcoming event near you. You can also sell your spare Clannad Concert Tickets on viagogo, and listing tickets is free. All Clannad tickets are covered by the viagogo Ticket guarantee!
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It comes that post are deleted which might be somehow a lose. I don't like to raise the discussion of wether it is good or bad if it comes that way, as every action comes back to the one who is doing so.
But to learn, refelct or even get the understanding of wholesome and unwholesome actions, it might be maybe good to do not delete them in a way, so that it is no more easy to reflect on what was going on.
I had seen, that some forum operator installed a kind of trash-topic for such posts.
Maybe it would be also good to clasify them in comparation with the forum rules which might be broken. That does not only give some support for the writer, but needs also more care and attention for the one who delets a post.
Over all, a post would be still readable and maybe from use for somebody.
The suggsetion does not claim that there is less care or less well-meant intention, but should be a additional possibility to train mindfulness and a source of reflection (for both, the poster and the moderator). Still the bord can be moderated (disarmed/defused) well as ever without putting the mines just away.
How ever, discussions of "it was right" or "it was wrong" should not be forced by it, as deeds are how ever already done.
The result would be that we are aware of trash and trash does not simply dissapear but give possibilities to refect of how kamma goes on.


text:
Re-EntryTrivia brain teasers have some element of trivia in them, but they are not just pure trivia questions.
What took 19 years to get into itself?
AnswerThe Guinness Book of Records, after 19 years of publication, became the second-best-selling book of all time and therefore got into itself.
What Next?
See another brain teaser just like this one...
Or, just get a random brain teaser
If you become a registered user you can vote on this brain teaser, keep track of
which ones you have seen, and even make your own.
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text:
Ogres Rajons Women T-Shirts are an Idakoos specialtiy! Idakoos has many things to offer. Whether you want to get a Ogres Rajons Women T-Shirt for a special occasion, give a Printed Ogres Rajons Women T-Shirt as a present or need to represent with a funny Ogres Rajons Tee during Holidays or Family and Friends get-togethers, Idakoos is sure to have the right Ogres Rajons Women T-Shirt for you! Even if it turns out you can't find the right Ogres Rajons Tshirt with the perfect design for your mother, father or children; Idakoos offers all of its men's women's and children's Ogres Rajons Tshirts as Custom Ogres Rajons Women T-Shirts. Personalize any Ogres Rajons Women T-Shirt the way you want to ensure the perfect gift.
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Academic Departments
Butler Community College has six academic divisions and three Early College Academies. Each division contains academic departments with faculty who are experts in their field and ready to help you find the best path to tomorrow. Our Academic Advisors will help you find a degree plan that fits your schedule and career goals or help you find courses that will transfer to your eventual four-year education choice.
Division of Academic SupportAdult Education
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Phi Theta Kappa (PTK)
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Biology (including Biotechnology and Environmental Studies)
Criminal Justice & Homeland Security
Fitness & Wellness (including Health and Physical Education)
Physical Sciences (including Physics, Astronomy, Geology, and Meteorology)
Division of Career & Technical EducationAccounting
Auto Collision Repair
Auto Technology
Business Administration
Business Medical Specialist
Business Systems Technology
Cyber Security & Internetworking Management
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Hospitality & Culinary Arts
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Early College AcademiesEarly College Health Sciences Academy
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text:
12 Ways to Use Bacon's Classy Cousin, Prosciutto
Zesty orange peels and high-quality chocolate create a custard-like texture in this loving dessert.
Get the recipe at Eating Richly.
Dig into toasted coconuts and melted dark chocolate adorned with crystallized ginger that will set perfectly on the dinner table, and even better in your stomach.
2 (14 ounces each) cans coconut milk
8 egg yolks
1/2 cup sugar
3/4 cup dark chocolate
2 tablespoons crystallized ginger, finely chopped
Heat oven to 300°F. Arrange eight (6-oz) ceramic or ovenproof ramekins in a baking dish with sides at least 2 inches high.
Heat coconut milk over medium heat until steaming. Be careful not to heat too quickly or the milk will scorch the bottom of the pan. Meanwhile, in a stainless steel bowl, whisk together egg yolks and sugar until smooth. Once coconut milk is steaming, remove from heat, add chocolate, and whisk until chocolate has melted completely. Slowly pour the milk mixture into the egg mixture, whisking constantly, to allow the milk to gradually bring up the temperature of the yolks so they don't scramble. Once the mixture is smooth, pour it into the ramekins. Sprinkle on ginger, distributing evenly.
Place baking dish on the middle rack of the oven. Pour enough water in the pan to come ½ to ¾ of the way up the outside of the ramekins. Bake until just set, 40 to 50 minutes. If you lightly jiggle the pan, the pots de crème should all move as one (like Jell-O). You can insert the tip of a stainless steel knife into the center to check that it comes out clean, or take the internal temperature with a thermometer, which should read 180 degrees F.
Serve hot or cold.
Recipe excerpted from: Sweet Cravings: 50 Seductive Desserts for a Gluten-Free Lifestyle by Kyra Bussanic; © 2013 Ten Speed Press Buy the book
Nutrient-Rich Recipes Inspired by the Colors of the Rainbow


text:
BECOME A PREFERRED SUBSCRIBER+ Get 15% off Your Next Order
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There are few things on the jobsite that are worse than cold, wet hands. With GEMPLER'S Waterproof Pigskin Work Gloves w/Safety cuff wrist, that's something you don't have to worry about. These waterproof work gloves use a 3-layer technology that blocks out water before it reaches your hands or the insulation. Unlike other waterproof/insulated gloves, ours are constructed of pigskin, which dries soft and supple. And, the Heatkeep® lining has been proven to be warmer than any other insulation material on the market. Safety cuff to protect your wrists. Brown color. One pair. GEMPLER'S Waterproof Pigskin Work Gloves w/Safety cuff wrist. Imported. Specify size from the drop-down menu above.
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2017 Reference Guide: Page 34


text:
Phase II Study With Abraxane, Bevacizumab and Carboplatin in Triple Negative Metastatic Breast Cancer (ABC)
This study has been completed.
Duke University
Genentech, Inc.
Celgene Corporation
Information provided by (Responsible Party):
Duke University
ClinicalTrials.gov Identifier:
First received: May 25, 2007
Last updated: January 29, 2015
Last verified: January 2015
- Full Text View
- Tabular View
- Study Results
- Disclaimer
- How to Read a Study Record
Detailed Description:
Taxanes (such as paclitaxel) are highly active to treat breast cancer. Abraxane® (nanoparticle albumin-bound paclitaxel) compared to standard paclitaxel improves efficacy and tolerability. When combined with a taxane, platinum agents improve response in metastatic breast cancer, with carboplatin conferring less toxicity than cisplatin. Monoclonal antibodies including bevacizumab target vascular endothelial growth factor (VEGF) to reduce angiogenesis. We hypothesize that the previously-untested combination of weekly Abraxane® and carboplatin plus biweekly bevacizumab will lengthen time to progression without producing intolerable toxicity.
|Breast Cancer
|Drug: Abraxane Drug: Bevacizumab Drug: Carboplatin
|Phase 2
|Study Type:
|Study Design:
|Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
|Official Title:
|A Phase II Study of Abraxane®, Carboplatin and Bevacizumab in "Triple Negative" (Demonstrating No Expression for Estrogen, Progesterone, or Her2 Receptors) Metastatic Breast Cancer
Resource links provided by NLM:
Genetics Home Reference related topics: breast cancer
MedlinePlus related topics: Breast Cancer
Drug Information available for: Paclitaxel Carboplatin BevacizumabU.S. FDA Resources
Further study details as provided by Duke University:
Primary Outcome Measures:
- Best Clinical Response Expressed as Percentage of Participants Treated With Combination Regimen of Weekly Abraxane® and Carboplatin Plus Biweekly Bevacizumab to Treat Women With Stage IV or Inoperable Stage III "Triple Negative" Metastatic Breast Cancer. [ Time Frame: 5 years ]Best clinical response is based on RECIST criteria, the proportion in each response category along with the exact binomial confidence intervals are estimated. Toxicity summaries are also provided.
Secondary Outcome Measures:
- Median Proportion Progression-free as Estimated by Kaplan-Meier Methods [ Time Frame: 5 years ]PFS was defined as time from trial enrollment to disease progression or death, whichever occurred first.
- To Evaluate Sequential Plasma Samples for Presence of Selected Angiogenic Markers [ Time Frame: 18 months ]
- to Determine if Apolipoprotein Alleles (Apo-E) Correlate With Treatment-related Neuropathy [ Time Frame: 18 months ]
- to Determine if SPARC Expression in Breast Tumors Predicts Progression-free Survival (PFS) [ Time Frame: 18 months ]
|Study Start Date:
|May 2007
|Study Completion Date:
|March 2014
|Primary Completion Date:
|March 2014 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: Abraxane, Carboplatin, Bevacizumab
Abraxane 100 mg/m2 IV over 30 min days 1,8,15.; Carboplatin AUC=2 IV over 15 min days 1,8,15., Bevacizumab 10 mg/kg IV days 1,15
Drug: Abraxane
100 mg/m2 IV over 30 min days 1,8,15. Cycles Repeated Every 28 days until documented evidence of disease progression by RECIST criteria, intolerable toxicity, or death..
Other Name: nanoparticle albumin-bound paclitaxelDrug: Bevacizumab
10 mg/kg IV days 1,15 Cycles Repeated Every 28 days until documented evidence of disease progression by RECIST criteria,intolerable toxicity, or death.
Other Name: AvastinDrug: Carboplatin
area under curve (AUC)=2 IV over 15 min days 1,8,15. Cycles Repeated Every 28 days until documented evidence of disease progression by RECIST criteria, intolerable toxicity, or death.
Detailed Description:
Anthracycline-based chemotherapy is widely used as adjuvant treatment for breast cancer. In addition to the challenge posed by anthracycline-induced cardiotoxicity, there are issues surrounding previous treatment with anthracyclines which limit its utility in the metastatic disease setting. Many patients with advanced disease will have had prior anthracycline-based adjuvant therapy, may have reached a maximum cumulative lifetime dose, or developed refractory disease, creating an obvious need for non-anthracycline treatment strategies.3 Platinum- and taxane-based chemotherapies as first-line therapy for metastatic breast cancer have demonstrated significant activity, producing single-agent response rates > 50%; in combination these rates increased to > 60% in both previously untreated and in patients who previously received anthracyclines.3 However, overall survival has remained relatively unchanged.4 As there is currently no standard of care for patients with metastatic breast cancer, various physical and psychological factors must be considered when evaluating chemotherapy treatment options, including the patient's tumor biology and growth rate, presence and extent of metastases, history of prior treatment and response, sensitivity and tolerance to therapy, and quality of life.2 Strategies to develop combination, higher dose, or sequential regimens using these active agents, while improving response rates and/or time to progression, may produce increased toxicity without increased survival.2 Because metastatic breast cancer remains essentially incurable using cytotoxic therapy alone, the study of targeted biologics offers new opportunities to enhance drug delivery via their ability to regulate specific receptors that are associated with clinically aggressive disease processes.
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Tissue block containing tumor to confirm metastatic breast cancer is required;
- Measurable disease according to RECIST criteria
- "Triple negative" disease defined as tumor demonstrating no expression for estrogen, progesterone or human epidermal growth factor receptor 2(HER2)receptors. "No expression" is categorized as ≤ 10% of cells staining or Allred ≤ 2;
- Aged 18 years or older;
- Eastern Cooperative Oncology Group (ECOG)/Zubrod performance status of 0 or 1; life expectancy ≥ 3 months;
- Patients may have received 0 - 1 prior therapies (except taxanes in the metastatic setting). An interval of at least 1 week must have elapsed since prior chemotherapy or hormonal therapy for metastatic disease; at least 6 months must have elapsed since prior adjuvant therapy;
- ≥ 2 weeks between surgery and study enrollment (≥ 4 weeks between major surgery (defined as open abdominal/thoracic/cardiac) and study enrollment;
Laboratory tests performed within 14 days of study entry:
- Granulocytes ≥ 1,500/µL;
- Platelets ≥ 100,000/µL;
- Hemoglobin ≥ 9 gm/dL;
- Total bilirubin ≤ institutional upper limit of normal (ULN);
Aspartate transaminase (AST) and alanine aminotransferase (ALT) ≤ 5 times ULN;
- Alkaline phosphatase ≤ 2.5 times ULN;
- Estimated creatinine clearance ≥ 60 mL/min.
- left ventricular ejection fraction (LVEF)≥ 50% by multigated acquisition (MUGA)/Echocardiogram;
- Informed consent to receive protocol treatment, to provide biologic specimens, and to complete neurotoxicity questionnaires;
- Cognitive and communication skills to comply with study and/or follow-up procedures;
No reproductive potential:
- If pre-menopausal: Negative serum pregnancy test and patient agreement to use adequate contraceptive method (abstinence, intrauterine device, barrier device with spermicide or surgical sterilization) during and for 3 months after completion of treatment.
- If post-menopausal: Amenorrhea for ≥ 12 months.
Exclusion Criteria:
- Pregnant or breast feeding;
- Prior treatment with Abraxane®, carboplatin or bevacizumab, or any taxane for metastatic breast cancer;
- Known hypersensitivity to any component of any study drug;
- Active infection;
- Current neuropathy ≥ grade 2;
- central nervous system (CNS) metastases as determined by head CT with contrast;
- History of bleeding within the past 6 months or active bleeding disorder;
- Serious non-healing wound, ulcer or bone fracture;
- Uncontrolled congestive heart failure (CHF), or history of myocardial infarction(MI), unstable angina, stroke, or transient ischemia within previous 6 months;
- Inadequately controlled hypertension (defined as systolic blood pressure < 150 and/or diastolic blood pressure > 100 mmHg on antihypertensive medications; prior history of hypertensive crisis or hypertensive encephalopathy;
- Proteinuria (defined as urine protein: creatinine (UPC) ratio ≥ 1.0 or urine dipstick ≥ 2+.
- Significant vascular disease (aortic aneurysm, aortic dissection) or symptomatic peripheral vascular disease;
- History of abdominal fistula, gastrointestinal perforation, or intra-abdominal abscess within previous 6 months;
- Uncontrolled serious contraindicated medical condition or psychiatric illness.
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00479674
Please refer to this study by its ClinicalTrials.gov identifier: NCT00479674
|United States, North Carolina
|Presbyterian Health Care
|Charlotte, North Carolina, United States, 28204
|Northeast Oncology Associates
|Concord, North Carolina, United States, 28205
|Duke University Medical Center
|Durham, North Carolina, United States, 27710
|Forsyth Regional Cancer Center
|Winston-Salem, North Carolina, United States, 27103-3019
Sponsors and Collaborators
Duke University
Genentech, Inc.
Celgene Corporation
|Principal Investigator:
|Kimberly Blackwell, MD
|Duke University
More Information
Additional Information:
Keywords provided by Duke University:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on September 21, 2017
Additional Information:
Nab- Paclitaxel/Bevacizumab/Carboplatin chemotherapy in the first line triple negative metastatic breast cancer
|Responsible Party:
|Duke University
|ClinicalTrials.gov Identifier:
|NCT00479674 History of Changes
|Other Study ID Numbers:
|Study First Received:
|May 25, 2007
|Results First Received:
|December 9, 2014
|Last Updated:
|January 29, 2015
Keywords provided by Duke University:
Metastatic Breast Cancer
Advanced Breast Cancer
Hormone Receptor AND Her2/neu Negative
Triple Negative
Triple Negative Breast Cancer
Stage IV or Inoperable Stage III Breast Cancer
Additional relevant MeSH terms:
Breast Neoplasms
Neoplasms by Site
Breast Diseases
Skin Diseases
Albumin-Bound Paclitaxel
Angiogenesis Inhibitors
Angiogenesis Modulating Agents
Growth Substances
Physiological Effects of Drugs
Growth Inhibitors
Antineoplastic Agents
Antineoplastic Agents, Phytogenic
Tubulin Modulators
Antimitotic Agents
Mitosis Modulators
Molecular Mechanisms of Pharmacological Action
ClinicalTrials.gov processed this record on September 21, 2017


text:
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Product Summary
Get a power boost! BoostBloc2000 from Et�n is a backup battery pack with a 2000mAH lithium ion battery that gives you long-lasting reliable power whenever and wherever you need it. Fast and effcient, when fully charged BoostBloc2000 fully charges most smartphones so you're never caught powerless.
With its sleek and elegant design, BoostBloc2000 fts in the palm of your hand.
BoostBloc2000 features a Micro-USB DC input to use with most smartphone chargers and a standard USB port for charging any mobile device. An LED charge indicator lets you monitor the battery charge level when you give it a quick shake. Whether you're on a plane or trekking in the woods, let BoostBloc2000 provide the power you need to stay fully charged wherever you are.
General Information
|Product Type
|Battery Power Adapter
|Manufacturer Part Number
|Manufacturer Website Address
|Eton Corporation
|Product Model
|Product Name
|BoostBloc2000 - Red
|Product Line
|Brand Name
Physical Characteristics
|Weight (Approximate)
|2.20 oz
|Form Factor
|USB Device
|Package Contents
|Limited Warranty
|1 Year
This product is shipped only within Canada and Warranty valid for Canada only.
Computer Valley makes every effort to provide accurate specifications, descriptions, images and price on all products that are found on www.computervalley.ca
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Problem Solver:
ECI Accessory Drive
Looking for a compact way to mount your A/C compressor and alternator? We're talking compact enough for lots of steering box clearance, fewer steering U-joints, and a bunch more exhaust options. The new Simplicity Engine and Accessory Mounting System from Engineered Components (ECI) might be your answer. The kit shown (PN EC-300) costs $375 and mounts to the front of the block using a total of eight attaching bolts; four at the bottom of the block, and four at the water pump attachment holes between the block and the pump. ECI says this provides an extremely rigid mount. Since no cylinder head or intake manifold attachment points are used, head and intake swaps are a breeze. And check out the engine mounts, which give the ECI kit a pro engine-plate look, only lighter, and without the fabrication hassle. ECI makes the kit for small-block Chevy V-belt applications with either short or long water pumps. Optional driver-side mounts are available for alternator and power steering pump mounting.
Engineered Components
New Wheels:
Center Line Legend
Center Line's new Legend Series two-piece wheel features the strength of a forged aluminum center and the manufacturing flexibility of a traditional rolled outer hoop. That means you get lots of fitment choices without paying a fortune for expensive three-piece wheels. The Legend is offered in everything from a 15-inch diameter, all the way up to 20-inch sizes, and widths ranging from 6 inches to 15 inches. That's a lot of baloney to put on the road! We're showing it here in the black "retro" look, but a polished version is also offered. Center Line also designed this wheel with an ample mounting pad in order to fit the larger aftermarket brake systems that require extra caliper clearance. We checked the pricing on the Legend Series at one of our favorite outlets, newstalgiawheel.com, and a typical 17×8 five-lug costs $404. While we were poking around the Center Line website, we also stumbled upon four other really cool new wheels for 2009–the Competition Series Qualifier, Competition Series Split-Spoke, Competition Series CRS1, and the Competition Series Nitro2. All of them would look absolutely bitchin' on a muscle car. Center Line's Legend Series 915, shown here in black "retro" trim, is designed for Pro Touring muscle cars with large brake packages. Sizes range from 15- to 20-inch diameter, and 6- to 15-inch widths. Weight on a typical 15-inch Legend is about 20 pounds.
Center Line Wheel
Challenger SRT-8:
Begin The Bolt-Ons!
It seemed like only yesterday that we were breaking the news about Dodge's milestone Challenger SRT-8 with its 425hp 6.1L Hemi. When they hit dealer lots, they were getting marked up to $50,000, sometimes more. And while the luster certainly hasn't lessened for us, we've recently spotted several examples of low-mileage SRT-8 Challengers on eBay going in the very low $30K range. This signals the time for real gearheads to pounce! MagnaFlow Performance actually got the ball rolling last summer with their stainless steel cat-back system, which is good for a dyno-proven 12 hp and 18 lb-ft of torque to the wheels. The 3-inch dual system uses the same mufflers found on winning Engine Masters Challenge engines, and retails for $1,619.18 with polished quad tips, or $1,293.89 using your stock tips.
Magnaflow Performance
Drop It & Stop It!
Classic Performance
It's very easy to get into trouble when you order spindles and brakes from different sources–the deal you thought you were getting sometimes goes up in smoke when the parts don't fit, or if they don't work together as a whole. Sometimes it can even happen with high-quality parts from different vendors, so paying big bucks is still no cure. The experts at Classic Performance Parts (CPP) have identified two situations in particular that arise: some companies' big brake kits don't always fit inside some 15-inch wheels, and some companies' drop spindles don't always work with some companies' 15-inch wheels. Interference problems abound with calipers, rims, and spindles, so CPP decided to make their own big brake kit and spindle that would work with the most popular Chevy models. The product line is called New School, and includes 2-inch drop spindles and 12-inch brake systems for '67-69 Camaro, '64-72 Chevelle, '68-74 Nova, and '55-64 fullsize cars.
Total Cost Involved:
Mustang Rear Suspension
Early Mustangs, like their ponycar counterparts at GM, have a rudimentary leaf-spring suspension based on economical compact car mechanicals. These inexpensive suspensions were great back in the day for bringing the initial cost of the car down, but here we are, 40-plus years later, trying to get these suspensions to do the impossible. In recent years, a lot had been done for GM's first-generation Camaro and Firebird, but the Mustang continued to lay fallow–until Total Cost Involved (TCI) took charge.
Rather than take a piecemeal bandage approach to the Mustang with upgraded leaf springs and shocks, TCI decided on a ground-up redesign, forsaking leaf springs for coilovers, a torque arm, and a Panhard bar. The choice is significant in that it banishes nearly every flaw of the original. The axle-mounted torque arm moves the axle's leverage point from the front leaf spring shackles to midcar, thus dramatically improving the instant center. Big improvements to launch bite, traction, and wheelhop are the result. The same geometry also results in decreased brake dive, which translates into more balanced braking. The Panhard part of the equation improves the lateral stability of the rearend while decoupling the rearend from vertical freedom of movement.
These kind of sweeping suspension upgrades usually require major, irrevocable surgery to the frame and body, but the TCI rear clip is completely bolt-on. Moreover, the TCI system makes significant use of supplemental chassis stiffeners, making it a prime candidate for serious road course or autocross cars. The TCI system includes subframe connectors, frame stiffener, torque arm bar, rear Panhard bar, frame brackets, All American coilover shocks, shock crossmember, rigid three-link, reinforcement plates, and pinion support bars.
Total Cost Involved


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Illegal tobacco and counterfeit cigarettes seized from newsagent
9:00am Monday 9th June 2014
By SNJ Reporter
9:00am Monday 9th June 2014
By SNJ Reporter
ON Tuesday 3rd June two trading standing officers seized 52 pouches of hand rolling tobacco (2.6kg) and 140 packs of cigarettes from a newsagent in Tredworth, Gloucester.
The seizure of the illegal products took place at 11.15am and the shop was open and staffed at the time. The shopkeeper will now be formally interviewed by trading standards officers.
The seized tobacco was kept in concealed storage both inside and outside the shop; it was immediately removed from the premises and will be destroyed.
Cllr Will Windsor-Clive, cabinet member for trading standards, said: "This is another successful investigation into an illegal industry that damages reputable businesses in the county.
"Counterfeit tobacco products can put people's health at greater risk and this type of activity will not be tolerated in Gloucestershire."
Eddie Coventry, head of Gloucestershire County Council's trading standards, said: "We encourage consumers to continue to report shops selling illegal tobacco because their valuable information can significantly help our investigations.
"We will remain vigilant and continue to take action to stop this criminal activity, which takes trade away from legitimate businesses in the county."
Andrea Dickens, spokeswoman for Smokefree South West, said: "Illegal tobacco is not a victimless crime as criminals would like us to believe.
"Not least, as there have been no taxes or duty paid, cigarettes and pouches of tobacco are offered to children at pocket money prices making it all too cheap and easy for them to smoke and become addicted."
© Copyright 2001-2017 Newsquest Media Group


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The Defense Department is setting up its first operational squadron of F-35 Joint Strike Fighter jets, the supersonic stealth aircraft intended to replace at least seven types of military aircraft flown by the United States and its allies.
Despite long-standing turbulence over the program — including sniping over its price tag, time line and ongoing technological development — the Marine Corps on Tuesday will redesignate a Hornet F/A-18 fighter jet squadron in Yuma as Marine Fighter Attack Squadron (VMFA) 121.
The F-35 squadron will be the Pentagon's first intended to eventually deploy in combat. Its inaugural jet, a B version designed for the Marine Corps to take off on short runways and land vertically like a helicopter, arrived Friday at Marine Corps Air Station Yuma.
The $396 billion F-35 program, the Pentagon's most expensive and by some measures most ambitious ever, has been under development by Lockheed Martin since 2001. Four years into initial production, the company has been delivering the third lot of Marine B models from its Fort Worth plant this fall.
The aircraft, also called the Lightning II, was conceived as a relatively affordable "fifth generation" stealth jet to be used across the services, saving money through a common production line, design and parts. Three versions were developed: one for the Marine Corps that would protect the service's ability to operate from short runways in austere locations and small amphibious ships, an Air Force model using conventional runways, and a Navy version for aircraft carriers.
As the Air Force tests and trains on its version and the Navy awaits delivery of its first production tailhook model, the Marine variant has faced the most scrutiny and danger of cancellation.
Former Secretary of Defense Robert Gates put the F-35B on probation, giving developers two years to fix technological and other problems or face cancellation. The B model was cleared from limbo in January, but some lawmakers have continued to press for cancellation to reduce overall F-35 program costs and help balance the federal budget.
With hands-on intervention in the program by the commandant, "we righted that ship," said Col. Kevin Killea, who oversees aviation requirements for the Marine Corps. Now the growing fleet of trained F-35 pilots and creation of the first operational squadron "tells me the program is progressing forward and meeting the time lines that the Marine Corps needs to transition out of the F/A-18 (Hornet) and the AV-8B (Harrier)," he said. "For me, if it stays on schedule and meets those time lines, it's more than a success; it's what we paid for."
Lockheed Martin officials called the new squadron a significant milestone for the program, showing confidence by the U.S. government in its safety and maturing design.
"These are not test airplanes. These are war-fighting machines that people will train on and become familiar with and ultimately deploy," said Eric Van Camp, Lockheed manager of F-35 Marine Corps business development.
Lockheed has produced about 65 of the 3,100 F-35 jets in the program of record. The models in operation have flown more than 5,000 hours, a majority of them in the first 10 months of this year, noted Steve O'Bryan, Lockheed's vice president for F-35 program integration and business development.
The Marines' short takeoff, vertical landing "B" model is doing particularly well, about 50 percent ahead of its flight test plan this year, he said. "You have an airplane both in production and technical maturity that continues to advance" at an accelerating pace, he said.
Richard Aboulafia, an aviation analyst and vice president for Teal Group, said the F-35 is still "far from ready" to deploy: "In terms of operational capability, it's extremely limited." But it is important for Lockheed and the Marine Corps to show the jet in action during development, he added.
"Of all the risks in the program, having a vertical landing model is certainly the most problematic and easily the one most mentioned as a possible budgetary casualty," Aboulafia said. The Marines also have the most at stake because of their aging fleet of fighter jets and lack of a modern fallback like the Navy and Air Force, he added.
"They need to make this program as firm as possible, both as a form of budgetary protection and to build a bridge from the legacy fleet to the next generation," Aboulafia said.
By December, the Marine Corps expects to have 17 of its 38 F-35 purchases contracted through 2012, said Capt. Richard Ulsh, a Marine Corps spokesman. Eventually the service hopes to acquire 420 F-35 jets, including 67 of the F-35C carrier version, assigned to 18 active squadrons, two reserve squadrons and two training squadrons.
The first squadron is not expected in San Diego at Marine Corps Air Station Miramar until fiscal 2021. The Navy expects to receive its first production jet in February, at Eglin Air Force Base, Fla., as it establishes the first F-35C training squadron.
Meanwhile, the military has been prepping pilots at the F-35 Integrated Training Center at Eglin and testing the aircraft at Edwards Air Force Base, Naval Air Station Patuxent River, Md., and at sea.
The new Yuma squadron has long been in the works. Lt. Col. Jeff Scott, commanding officer of VMFA-121, was selected for the job two years ago. The Harrier pilot and two-time Iraq combat veteran finished his F-35 conversion training at Eglin last week.
"It's an amazing airplane, it flies extremely well. It is not just the next step in aircraft, it is five or six steps beyond what we currently have. It is growing into those capabilities in terms of the software and (flight) testing," Scott said, but compared with the Corps' current vertical landing jet — the Harrier introduced in the '80s — it is faster, more stable, more maneuverable and easier to fly because of computerized flight controls.
"The integrated sensors of the aircraft are extremely impressive. The computer does a lot of the work. The computer sorts out a lot of things and gives the pilots a lot of information," Scott said.
The squadron has about half of the 300 personnel it needs and four pilots qualified to fly the 16 jets that will eventually be assigned to the unit. It is also the first to have its own maintenance crews currently training to service the aircraft, instead of relying on Lockheed contractors.
The squadron hopes to be cleared by the 3rd Marine Aircraft Wing and the Commander of Naval Air Forces to fly around Yuma by late December or early January, pending inspection of its maintenance and other processes.
Tactical training may begin within a year after 10 to 12 pilots are qualified to fly. But the squadron won't be able to deploy until it has jets with block 2B software revisions, which Lockheed said it expects to deliver in mid-2015.
Currently only F-35 test pilots are allowed to operate the F-35B's signature feature in flight — its ability to land vertically. That should change for the Yuma pilots within a year, said Maj. Aric Liberman, a former Navy SEAL turned Hornet pilot who will be the aviation maintenance officer for VMFA-121.
Liberman has been stationed at Eglin for more than three years, training on the F-35 mostly on simulators. He took his first flight in the new jet in August.
After powering up and rolling down the runway, his 40-minute midmorning cruise over the Gulf of Mexico was "business as usual," he recalled. "It was the most exciting nonevent I've ever done in my life, because the jet is so easy to fly and because I had so much preparation."
Flying the F-35 that first time was similar to flying a Hornet, except for the helmet-mounted display, touch-screen controls on the glass cockpit, and the added thrill that "it's a new aircraft and you're on the edge of Marine Corps aviation."
It seemed like a slow start getting the program off the ground. Now the squadron will have a lot of work and learning to do in coming years to help the Marine Corps integrate the F-35 into its operations, Liberman said.
"We've really gained a lot of momentum," he said. "I am excited to make that transition. That is what we are here to do — to learn how to employ the aircraft as a weapon system."


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Burton Scout Sock
Midweight warmth meets rider-specific support and cushioning. An everyday necessity.
When does a sock become more than just a sock? At what point does it go from something you simply wear on your feet, to something your feet can't live without? The women's Burton Scout Sock walks the line between total comfort and absolute dependency. It's quick-drying, breathable blend of midweight insulating fibers and strategically placed cushioning make it the optimal all-season snowboard sock. The Stay High band wraps it around your calves to prevent slippage while strategic reinforcements beef up abrasion resistance in the areas where snowboard socks see the most abuse.
- 63% Acrylic, 24% Nylon, 11% Polypropylene, 2% Spandex
- Quick-Drying and Odor-Resistant Polypropylene Reinforced Footbed
- Medium-Density Cushioning Throughout Sock
Elastic Arch and Ankle Support
Elastic Arch and Ankle Support
Added elasticity and padding underneath the arch and around the ankle increases support and cushioning where it matters most.
Chafe-Free Link Toe Seam
Chafe-Free Link Toe Seam
Flat-stitched toe seam eliminates chafe and bunching for a better fit inside your boots.
- Reinforced Toe and Heel
Stay High Comfort Band
Stay High Comfort Band
It's easy to stay high with a band that keeps the sock locked around your calf thanks to a soft elastic band that reduces sagging and bunching.
- Midweight
Burton's W48 Warranty Program
Burton's W48 Warranty Program
W48 is our Product Service Program: We'll have your claim repaired or replaced and on its way back to you within 2 business days of receiving the item. It's all part of Burton's commitment to get you back out there as quickly as possible.


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well. the thing is i do. and now the only message i get is that i should go online to buy the game. whats my next step? the game still shows in my library on telltales website, and i certainly still have the charge on my card.
The last time i faced a terrible launch such as this it was diablo 3, an unfortunately online always game. whats your excuse? im sure im not in the minority of people who dont have endless time to play games, and i was planning to use my 1 day off this week for that. Should i ask for a refund? im sure ill love your product, just maybe someone else wants me to jump through less hoops to play it and they deserve my money.


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One hundred years ago, the people of Toledo declared "You will do better in Toledo." and the slogan resonates today.
People from around the city are voicing their thoughts on how they are doing better in Toledo in a short video produced by John Amato of JUPMODE and Josh Wagy of Smash Toledo in honor of the 100th anniversary of the slogan.
The adage dates back to 1913 when the Toledo Commerce Club held a contest to create a new slogan for the city. More than 7,000 entries were submitted and four people came up with "You will do better in Toledo." C.W. Lammers was the first to submit the slogan and was declared the winner.
In 1913, the slogan was illuminated with 7,000 lights on a sign hung from the top of the Valentine Building at Adams and St. Clair streets. The sign alternated between three images: A locomotive, the slogan and a lake freighter. It weighed 25 tons and measured 76 feet long by 68 feet high, though other reports list it as 100 feet by 58 feet.
In 2008, The Blade published a book, "You Will Do Better in Toledo: From Frogtown to Glass City, A Toledo Retrospective in Postcards, 1893-1929," that showcases a picture postcard of the sign on the book's cover. It describes the day the sign was unveiled: "The sign was accepted by Mayor Brand Whitlock and first lit on December 17, 1913. According to The Toledo Blade from the following day, '8,000 spectators jammed into St. Clair St., between Madison Ave. and Adams St. to view the sign.'"
The sign stayed until 1926 when the city offices moved from the Valentine Building to the Safety Building. Bill Colter, facility manager at The Valentine Theatre, said the baseboard that held the sign can still be seen on the building's roof, although it isn't visible from the street.
Donna Christian with the Toledo-Lucas County Public Library's Local History and Genealogy Department said she suspects the sign was discarded because none of her sources say what happened to it. Local historian John Husman agreed no one seems to know the fate of the sign.
Toledo Railways Light Co., which donated the sign to the city, split into Community Traction Company for the streetcar business and Toledo Edison for the electric business, the year the sign was removed, Christian said.
'Cool saying'
The original sign may not exist today, but its legacy endures at Wesley's Bar Grill on Adams Street, where a replica sign hangs on the northern wall. Owner Michael Roberts, a former student of history at the University of Toledo, had the sign custom made in 2006.
"It's a cool saying," Roberts said. "Everybody else likes it now. Funny how it was dormant for decades."
Burger Bar 419 employees also sport the slogan on their shirts, printed by Amato, whose T-shirt company has gained popularity since printing the slogan.
"It's a quintessential slogan for Toledo," Amato said. "It's not just because of a shirt. It's because [Toledo] Mayor Mike Bell wears a ['You will do better in Toledo'] shirt. There's a lot of support for it."
Because the slogan is Amato's flagship design, he decided to commemorate its anniversary with a short video, asking people of all ages, races and backgrounds how they have fared better in Toledo.
"We just wanted to get a compilation of all the great reasons why people live and do well in Toledo," Amato said. "We have 25 [voices] already and we're hoping for 50."
Those voices include news anchor Chrys Peterson of WTOL-11, professional golfer Pat Lindsey and Bell, among others, Wagy said.
"The reason I believe you will [be] better in Toledo is because of the people," Bell said in the video. "I've traveled across the world and met people from around the globe and some of the best and nicest people are right here in Toledo."
Amato and Wagy's video will be posted to social media, where they hope it will go viral. The launch date is set for the anniversary of the sign's unveiling, Dec. 17.
The slogan has wide appeal and is unique to Toledo, Amato said, adding that although the slogan originated in the 1900s, it's still familiar to people today.
"Toledo is a great city," Amato said. "It's a great place to raise kids. We have an amazing zoo and art museum, we have two great universities in the area, our Metroparks are incredible, our people are friendly and hard-working, we have two great minor league sports teams, we are the home of the industrial glass revolution and art glass revival. There are many reasons I've left out."
Christine Bailey of the Toledo Regional Chamber of Commerce agrees with Amato's assessment. Bailey, the communications manager at the chamber, said times do change but the ability to create opportunity in Toledo has withstood the test of time.
"In Toledo, we've got a lot of great aspects: water, rail, the people," Bailey said. "Times change but we still have a lot of the good, raw material to create opportunity here. That is what the chamber still believes in and that is what we support. We are not without challenges, but we still think people will do well in Toledo."
Lifelong love
Business owner Steve Crouse has a lifelong love of Toledo — 30 years long. He's collected Toledo memorabilia that hangs in his Downtown Glass City Cafe. He's also the owner of Erd Specialty Graphics on Monroe Street.
Both businesses have their ups and downs, he said, but he believes he wouldn't have had the same business opportunities in another town as he has had in Toledo.
Restaurateur Trevor Deeter of Deet's BBQ agrees. He started in the food business with his father and stepmother three years ago amid cries of "You'll never succeed."
Critics told him the economy was bad. After the restaurant's first year, however, it expanded to a new location and then proceeded to burst those seams, Deeter said. The customer support has been "overwhelming," considering that the Maumee restaurant does little advertising, relying mostly on word of mouth, he said.
Deeter not only sees the support of Toledoans through his restaurant, but in his dealings around town. As a driver for the Salvation Army's Toys for Tots program, he picks up toys at donation centers with his father, Bob Deeter. He said he was amazed at the level of giving this year.
Jeff Schaaf is the brand manager of Toledo Region, a branding initiative with a goal to promote Northwest Ohio and attract talent to the area. The "You will do better in Toledo" slogan reinforces the goals of his program, Schaaf said.
"It supports what we're tying to do, to enforce that Toledo is a good place to live, work and enjoy," he said. "When someone says, 'Yeah, you will do better in Toledo' because of x, y, z, I think that's the way the campaign was started in Toledo, to show that Toledo is just as good as any other city. It fits into the message we're trying to convey.
"We're trying to say, 'Don't look at the negative stuff; look at the good stuff,'" Schaaf continued. "There are a ton of fun things to do in Toledo."
Toledo is "doing better" because it's affordable and accessible, said Bill Thomas, executive director of the Downtown Toledo Development Corporation. People are "doing better" because Toledo is experiencing the "re-urbanization" of Downtown, he said.
"People want to live here, play here, work here, shop here, all within walking distance," Thomas said in an email. "The Downtown is the same size as the Franklin Park Mall. That is evidence that our Downtown is walkable."
To honor the slogan's 100th anniversary, Wesley's is hosting a celebration for the public on Dec. 17. The bar opens at 3 p.m. Drink specials will be available along with "You will do better in Toledo" drink koozies and stickers provided by Amato.
Tags: 100th Anniversary, Bill Thomas executive director of the Downtown Toledo Development Corporation, Burger Bar, C.W. Lammers, Donna Christian with the Toledo-Lucas County Public Library's Local History and Genealogy Department, Downtown Glass City Cafe, Frogtown, Glass City, Jeff Schaaf is the brand manager of Toledo Region, John Amato, JUPMODE, Local historian John Husman, Mayor Brand Whitlock, Restaurateur Trevor Deeter of Deet's BBQ, Salvation Army's Toys for Tots program, Smash Toledo, The Blade, The Valentine Theatre, Toledo Commerce Club, Toledo Edison, Toledo Railways Light Co., University of Toledo, Valentine Building, Wesley's Bar Grill
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Originally posted 2013-12-13 09:19:19.
Article source: http://www.toledofreepress.com/2013/12/12/video-celebrates-100th-anniversary-of-toledo-slogan/


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