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A MiG-29KUB factory development prototype made a successful landing on the deck of the INS Vikramaditya aircraft carrier on July 28, according to Russian Aircraft ("MiG"). The Indian carrier is undergoing sea trials in the Barents Sea after modernization and refit from its previous life as a Soviet heavy cruiser. Test pilots Mikhail Belyaev and Nikolai Diorditsa were at the controls for the first landing, and a few days later they performed the first takeoff from the carrier and then made a second successful deck landing.
The successful MiG landing and other progress in the open-sea trials of the Vikramaditya have encouraged the Russians to approach the Indian MoD with a proposal to build an all-new aircraft carrier in Russia for the Indian navy. The vessel would be built at the same Sevmash shipyard at Severodvinsk that reworked the Vikramaditya. The new ship, however, would have nuclear or gas-turbine propulsion. The Vikramaditya's water boilers run on diesel.
The Nevskoye design bureau in St. Petersburg has been working on a next-generation carrier for the Russian navy since 2005. It has already produced several design proposals and submitted them to the Russian navy for assessment. It is believed that the new carrier on offer to India will be based on one of these proposals. Construction would take between seven and 10 years, according to Andrei Diachkov, president of Russia's United Shipbuilding (OSK). He further stated that OSK is ready to assist India in the indigenous construction of aircraft carriers, through a joint venture being established between Russian and Indian shipbuilders.
However, a high-ranking source in the Russian navy said that that service wants a ship "a lot more advanced than the one on offer" from Nevskoye. The Russian navy's "dream" carrier would be armed with advanced self-defense systems able to intercept high-flying targets, including low-orbiting satellites. It should also have "underwater capability," the source said, hinting at the ability of the carrier to carry advanced manned or unmanned submersible vessels. The navy expects the Nevskoye design house to complete the draft design of an advanced ship in 2014, then issue production documentation in time for Sevmash to begin construction in 2020.
In late July, newly appointed Russian navy commander Admiral Victor Chirkov confirmed that "money [to prepare] for the construction of such ships has been allocated." However, he also said then that the current Russian Armament Program 2011-2020 does not include the construction of such ships and that a decision on the program has not been made yet. By 2020, he added, the MoD will be spending its money on construction of smaller-displacement ships and modernization of older nuclear-powered cruisers.
Chris Coombs (not verified)
August 10, 2012 - 4:42pm
There are only two man made vessels at sea, submarines and targets.
Dalmatian28 (not verified)
August 16, 2012 - 2:25am
I can't agree with you more! Russian generals are like water buffalo...fat, powerful but very slow to adopt. I would get rid of even subs, just keep network of listening stations and develop great torpedoes that you can drop from the airplane.
This is the age of hypersonic weapons....this junk will make a great target for practice shooting. Very stupid way to burn billions!
Matt (not verified)
August 18, 2012 - 11:30am
"This is the age of hypersonic weapons....this junk will make a great target for practice shooting. Very stupid way to burn billions!"
Tell that to the US Navy, Indian Navy, PLAN, Royal Navy, Marine Nationale, because they should probably be informed before they waste untold billions on the junk targets they are building in this hypersonic age
Your lack of knowledge is astounding

subset: commoncrawl


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2013 Beaver Outlaw Run 1/2 Marathon & 5k
Beaver, Utah
Sat 08/10/2013
5K, Half Marathon
200 Participants
Half participants will receive a "Dry Zone" shirt (Men & Women's sizes). 5k participants will recieve a t-shirt. All Half finishers will receive a finishers metal! Packet pickup: August 17, 5:30pm to 8:00pm at the Tushar Mountain SportsComplex or Saturday morning 6:00am-6:30 am before the race. All 1/2 marathon participants please join us for a pre-race dinner August 17 at 6:30pm sponsored by the official race hotel, Days Inn. Dinner is included in your registration fee and you can purchase addional tickets for $10.00 a person for a guest. 5k participants can purchase pre-race dinner tickets for $10.00 a person. Awards will be given to the first 3 places in the following age divisions. mens/women's divisions 12 and under 13-19 20-29 30-39 40-49 50-59 60+ Check us out on Facebook! Check out our Beaver County Fair!
- Address:600 North 900 East
Beaver, UT 84713


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Christ the RedeemerJeff Bumgardner, Joel Lindsey & Daniel Semsen - Brentwood-Benson Publishing
Christ the RedeemerJeff Bumgardner, Joel Lindsey & Daniel Semsen - Brentwood-Benson Publishing
Leaving His throne and the perfection of heaven, Christ entered our world as the only hope for mankind. After His resurrection Christ conquered the grave and defeated sin and death, showing Himself to be not only the Lamb of God, slain for our sins, but also the victorious Redeemer and risen King! Songs include: Glorious, Glorious; Christ the Redeemer; Christ the Redeemer Underscore; Fit For a King; The Garden Medley (Christ the Redeemer with O Sacred Head, Now Wounded with My Jesus, I Love Thee); Beneath the Cross Medley (Beneath the Cross of Jesus with Christ the Redeemer with The Old Rugged Cross) and Christ the Redeemer (Reprise) with Christ Arose. Performance time: 23 minutes.
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text:
Rangers trade Gimenez to Indians
ARLINGTON -- The Rangers traded catcher Chris Gimenez to the Indians for future considerations Saturday. Gimenez, who accepted his outright assignment to Triple-A Round Rock last Tuesday, will join Cleveland's big league team.
Gimenez batted .262 with a .331 on-base percentage, .355 slugging percentage and 11 RBIs in 33 games with Rangers. He made 29 starts, 26 at catcher and three at first base. Gimenez hit .284 with six home runs and 22 RBIs in 39 games with Round Rock, which is on the road in Salt Lake City while the Indians are currently hosting the Astros.
The 31-year-old began Spring Training this year with the A's before the Rangers claimed him off waivers three days before Opening Day. Needing depth at catcher with Geovany Soto beginning the season on the 60-day disabled list, Gimenez was one of three catchers to make the Rangers' Opening Day roster.
Gimenez was designated for assignment just one day after the Rangers' season opener and later released, only to be re-signed less than a week later on April 10. He spent more than a month with Triple-A Round Rock before being called up May 20. Five days after being placed on paternity leave Aug. 4 as his wife was preparing to give birth, Gimenez was again designated for assignment.
This time, he accepted his outright assignment to Round Rock, where he hit .400 with two homers and six RBIs in seven games before being traded Saturday.
Christian Corona is a contributor to MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.


text:
Preston Patchwork Quilt + Sham
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We mixed and matched our favorite plaids and stripes to create this perfectly cozy quilt. It's woven of ultrasmooth, yarn-dyed and printed cotton percale.
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text:
Syndergaard out for week with left shoulder sprain
SAN FRANCISCO -- The Mets' top prospect, right-hander Noah Syndergaard, appears to have avoided the worst.
X-rays and a CT scan performed on Syndergaard's left shoulder on Friday came up negative for a possible fracture of the scapula bone, according to a team release. Doctors diagnosed Syndergaard with a sprained A/C joint in his left shoulder, recommending he refrain from throwing for five to seven days. He can resume baseball activity as tolerated thereafter.
The Mets' top-ranked player on MLB.com's 2014 Prospect Watch, Syndergaard sprained his shoulder attempting to make a tag play at home plate in the first inning on Thursday at Triple-A Las Vegas. He gave up three runs in two-thirds of an inning prior to leaving his first game action since May 21 after missing time due to an unrelated injury.
Syndergaard has struggled in his first taste of Triple-A, posting a 4.47 ERA in 11 starts, yet he has flashed plenty of potential throughout the early summer, striking out 57 against 19 walks in 54 1/3 innings.
He began the season as a candidate to be a first-half callup, perhaps as soon as June. Injuries -- including a mild flexor-pronator strain that sidelined him from late May into June -- have delayed his timetable, though there is a strong chance he could debut later this summer.
Anthony DiComo is a reporter for MLB.com. Follow him on Twitter @AnthonyDicomo. This story was not subject to the approval of Major League Baseball or its clubs.


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The La Plata Community Clinic, with medical personnel and support staff members working pro bono, has opened without fanfare.
The soft opening was the result of uncertainty, Executive Director Harriet Brandstetter said Friday.
It was the first day, so we didnt know how it would go, she said. But it went marvelously. Dr. Megan Lewis saw eight or nine patients in the morning.
A project long in development, the clinic has the goal of serving the medical and dental needs of the working poor, the homeless, the uninsured and low-income adults.
La Plata County came up short of health care in 2007 when Valley-Wide Health Systems closed its center in Durango. Voters subsequently rejected a proposal to tax themselves for a health-service district.
The clinic will help close a gap in care that has existed for years. For people such as David Tarr, who has had issues with his teeth, it can mean a dramatic quality-of-life improvement.
Tarr was there Monday to see Jim Abramowitz, a retired dentist, who is providing his services free, as are all other professionals at the clinic.
When I started to practice in Denver in 1972, pro bono work was expected of you, Abramowitz said while filling two teeth for Tarr.
Tarr lost teeth to a hockey puck as a youngster in Los Angeles and received implants. As an adult, he had teeth knocked out when he fell through a roof on a job, and later a fall during a seizure dislodged a tooth.
Tarr was effusive in his praise of clinic personnel.
Theyre people who actually care, Tarr said. Thank God for this place. Its a blessing that makes me see the world in a different light.
The mission of the clinic is to cover basic health problems. Doctors see patients with such complaints as the flu, an earache or diabetes. Dentists do fillings or extractions.
Care is not free. All patients pay something based on income, family size and absence of any medical or dental insurance. All patients must be residents of La Plata County.
Brandstetter said medical and nonmedical volunteers have been scheduled to cover shifts for the remainder of the month. And until funding becomes available, the clinic will rely on volunteers to keep the doors open, she said.
Jaynee Fontecchio, a registered nurse and director of the Citizens Health Advisory Council, which brought about the creation of the community clinic, is upbeat.
This has been quite an endeavor, Fontecchio said Friday. But this is such a giving community that I think that once we get going there will be more volunteers instead of fewer.
There is no way to continue without volunteer providers, she said.
The Karakin Foundation provided seed money to establish the clinic, and it will provide about $200,000 this year for rent, utilities and Brandstetters salary, Fontecchio said.
The Citizens Health Advisory Council is one of the organizations that has emerged from the fluid population of health-care professionals and others interested in improving health care in the county.
Im so appreciative that members of the citizens council saw the need and were so persistent and fruitful, Brandstetter said.
Brandstetter was hired last year from the La Clínica de Familia in Las Cruces, N.M., where she was the CEO. The organization had nine clinics and 350 paid employees, she said.
In excess of 50 percent of our patients were uninsured, Brandstetter said. We received federal, state, county and city money.


text:
Keppinger sidelined by irritation in shoulder
GLENDALE, Ariz. -- The White Sox scratched Jeff Keppinger from Sunday's starting lineup during split-squad action in Peoria due to slight right shoulder irritation. Keppinger, whose offseason throwing program was delayed when he broke his right fibula in a fall at home, has been bothered by the sore shoulder through the early stages of Spring Training.
But three weeks still remain before the start of the regular season, so manager Robin Ventura isn't worried about this minor setback.
"Just feeling sore. It's just one of those, monitoring it," Ventura said. "He could have played but we're going to keep him out and see how it looks tomorrow.
Keppinger could serve as designated hitter Monday against the Rockies but won't play in the field or throw until Wednesday. His absence gives more playing time to Conor Gillaspie, who had two hits in Sunday's loss to the Reds in Glendale, and Brent Morel, who homered among his two hits in Peoria.
"That's something that's good when that stuff happens," Venutra said. "We put somebody else in there and move them around and we get to see these younger kids. You get some information for later on down the road.
"We're not concerned about [Keppinger's] playing time down here. Today you just get that chance because of the split squad, you can get everyone in there and play."
Scott Merkin is a reporter for MLB.com. Read his blog, Merk's Works, and follow him on Twitter @scottmerkin. This story was not subject to the approval of Major League Baseball or its clubs.


text:
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All Burton apparel is backed by a one-year warranty from date of purchase. Our W48 Warranty Program ensures that should you have a problem, we'll have your claim repaired or replaced and on its way back to you within two business days of receiving it.


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Topic: Starting Sorafenib next week
Hey Y'all!
Looks like I have been accepted into the sorafenib trial and should get started next week. My oncologist says it's already approved and being used in renal cancer with great results - 78% have arrested growth of tumors. We're going to give this a whirl while I have some time. We may look at another clinical trial, but chemo will be the ultimate back-up.
We will make the drive from Ouray, Colorado to Dodge City, Kansas on March 15th, see the doctor on March 16th, and return home on the 17th which is St. Patrick's Day. (I'm scheduled to play in a Celtic band on that night at the Elks Club and the following night at a local restaurant, so there will be no lingering along the Santa Fe Trail on this initial trip.) We do hope to stop at Bent's Old Fort in eastern Colorado on the way there.
I got word yesterday that my insurance company will cover the clinical trial. My doctor wrote a letter to persuade/insist that they cover this. The selling point seemed to be that the drug would be free as opposed to the cost chemotherapy drugs.
Wish me luck,


text: British clothier calls West Virginia home By Sandy Wells May 5, 2013 Story Share Chris Dorst In his Lee Street headquarters, London-born Richard Emery goes about the business of providing custom-made suits and shirts as the state representative for Tom James, an exclusive clothing company that also offers attire for women, ready-made clothing and a full line of wardrobe accessories. Looking for a $200 tie? Chris Dorst "The whole concept is, ... Chris Dorst ... we come to you. ... Chris Dorst ... I call clients and go to their office or home." Courtesy photo In 1989, Richard Emery was photographed in front of the Taj Mahal during a trip to India to develop products and manufacturing contracts for embossed leather goods. Courtesy photo A schoolboy portrait recalls Richard Emery's upbringing in a small village outside London. Courtesy photo As a 12-year-old, Richard Emery's distinctive dimples punctuated every smile. Courtesy photo A British photographer coached picture-perfect smiles from Richard Emery and his sister, Vicky. Courtesy photo Siblings Vicky and Richard Emery enjoy a moment on the lap of their father, a London factory worker. CHARLESTON, W.Va. -- He's a long way from London, a quantum leap from his blue-collar British roots to the high-falutin' clients he serves from his office on Lee Street.No one finds that journey more remarkable than Richard Emery himself. In 1979, at 22, he packed his punk rock garb and flew to a place called West Virginia to work as a tool-and-die maker for Volkswagen in South Charleston.Those die-making skills led, of all things, to embossing and designing handbags in Palm Beach. He traveled extensively in India, Hong Kong and Thailand to engage manufacturers for the leather goods he developed. He traveled throughout America selling the purses and other products.In 1995, he returned to Charleston where he runs the state office for Tom James, a custom-made clothier catering to discerning shakers and movers. That telltale cockney accent reflects his upbringing, but West Virginia has his heart. A U.S. citizen since 1986, our 56-year-old London transplant calls Charleston home, a hillbilly by choice. "I was born in London. Most people say I have a cockney accent, but when I go back to England, they say I sound more American. Most people think I'm from Australia now. I've been over here so long, I have bastardized the British accent."I was in Hazard, Ky., one time, and I cut somebody off, and they were not pleased with me. So I put on my best British accent and apologized profusely. I told them I had just arrived here from London, a little white lie. They said, 'Oh, don't worry about it.' I use the accent when I need it. "About 1960, my parents moved outside of London to a small village, like a subdivision. My dad worked for a ball-bearing factory and then for General Motors. We were a working-class family."Back then, you could leave school at 15 but nobody knew what they wanted to do at 15, so I stayed until I was 16 when I went into an apprenticeship as a tool-and-die maker."I did a four-year apprenticeship and then worked three years outside my apprenticeship."One day, I was home reading a local newspaper, and it had an advertisement for a tool-and-die maker in Charleston, W.Va. I asked somebody where Charleston was and they said, 'Oh, that's where the Confederacy was born.' They thought it was Charleston, S.C."I applied for the job with five other guys. Four of us got the job. I was 22. I moved here on April 21, 1979. Volkswagen flew us over and put us up in the Ramada in South Charleston for two weeks and paid all our expenses. "They took 12 of us to Car City Motors owned by Paul and C.E. White. They sold 12 cars in one day. We would say, 'How much is that?' Paul would go, 'Oh, about $3,500.' We'd say, 'We'll take it.' No negotiating. We didn't have Social Security numbers or anything. Paul White took a huge risk. "People were nice to us and fascinated. Back in '79, there were not too many British people here. We were a little bit of a novelty."Coming from England, I always liked clothes and fashion. I grew up in that punk rock era where you dyed your hair. When I came over, I had about five earrings, and that freaked everybody out. I was an oddball. No one was dressed like we were."On Memorial Day, we went to Myrtle Beach. Before we left, we met this guy who said, 'If you go anywhere and there are a bunch of people having a good time, there will be someone from West Virginia in the center of it.'"So we go to the beach, and there is this guy with a boom box and a cooler sitting on the beach in a deck chair having a giddy-up good time. He asked us where we were from. We said, 'We live in Charleston, W.Va.' He said, 'So do I.'"My plan was, if I didn't like it here, I would stay two years, earn as much money as I could, tour the states and go home. But I worked for Volkswagen for eight years. When they moved their operation to Mexico, I was left unemployed. I was dating a girl from Florida, so I went there and worked for a fashion-accessory company."The guy had a handbag company. He was embossing them. Tool-and-die is kind of like embossing. He made that connection. He hired me in October of '87. "By November, I was in Bombay and Calcutta. He sent me to India to build a product line for him. I came back with what he said was the best product line he ever had. The company went from doing $3 million a year to $18 million. "I went over with a lot of ideas and worked with the vendors. The bags were hand-painted and printed. I took a lot of prints and postcards. I would say, 'I want this. Put the state of Texas on the handbag.' In Texas, they loved it."I opened a company in India for the Mediterranean Trading Co. and hired about 30 people over there, which essentially put me out of a job. That's how I made the leap into sales."I started selling handbags to Wal-Mart, JC Penney, Claire's Boutique, the mass market, and we did very well. You still see some of them today, especially in Texas. They loved that Texas bag."After eight strong years, the company wasn't doing well. It went out of business. The guy who owned it wanted to go into politics."A friend found this job for me. The timing was perfect. I got laid off in December of 1994 and started working for Tom James in January 1995."A guy who worked out of Lexington had a little office in Huntington and hired me to work the Charleston area. He moved to Puerto Rico, so I just moved the whole office here. I opened this store Thanksgiving of '95."Tom James was formed in 1966. We are the largest custom clothier in the world and the largest wool importer in the U.S. We used to make clothes for royalty. So we've been in business a long time."We sell custom and ready-made clothes. The whole concept is, we come to you. I call my clients and go to their office or home. I measure them and show them fabrics and take pictures of them. I went into training to learn how to measure and fit. A custom suit can go anywhere from $599 to $24,000."I had a guy come in who said he had no dress clothes. He bought five or six suits and sport coats. It came to about $40,000. When he put the clothes on, his wife cried. She said she had never seen him look so good."There was a guy who had been in an accident. He had no movement in his elbow. And he was very large. He couldn't stand up very long. Stores didn't treat him well. So he called me. I went to his house. The suit was for his son's wedding. He said it was the only suit he would ever own. He said he would be buried in it."I'm as busy as I want to be. Last year was the best year I've ever had with Tom James. I got into the President's Club, a level of leadership with Tom James."I think I have a great work ethic. I'm in here at 7:30 and work until the job is finished. Referrals are the best source of business. But starting out, I made a lot of cold calls."Most men don't like to go shopping. I called this one guy, a cold call, and he was very aggravated. He told me nicely but firmly that he was going to hang up. I asked if he would give me 10 seconds to tell him what I do and if he didn't like it, he could just tell me to stop. He said, 'Fine. You have 10 seconds.'"I went through the spiel, and he said, 'Richard, Richard, stop, stop.' I thought, oh, no. He said, 'The one thing I hate worse than cold calls is shopping for clothing. You've bought yourself two minutes. Slow down and tell me what you do.' And he has become a client."It takes from four to six weeks for a suit, six to eight weeks for a shirt. But there's something to be said for a suit or shirt made especially for you."I'm a high school soccer referee. I was voted state referee of the year in 2009. I used to coach a little, but there was a shortage of referees. I'd been around soccer -- we call it football in England -- all my life. I'm a huge Manchester United soccer fan. My license plate is Man UTD."Coaches and players don't know the rules. It can get pretty intimidating. The parents are dreadful sometimes."I love this valley. I try to stay involved. Beth Wallace, my girlfriend, has a daughter, Jordan, who goes to UC. I go to a lot of her functions."Charleston has given me a good living twice. This is my home. People here are fantastic."I go to England once a year. Last Christmas, I took my dad to see a James Bond movie. That was our thing when I was young. I must have seen 'Goldfinger' at least 20 times."When I was 20, I would never have envisioned me doing what I'm doing now. But I will be here until I retire."I want to expand this business, maybe open up in the Morgantown area and train somebody who can carry the torch when I leave here." Reach Sandy Wells at firstname.lastname@example.com or 304-348-5173. Story Share Story Share Trending Now 1 Philanthropist Betty Schoenbaum of Shoney's fortune turns 100 2 Derek Redd: Marshall thinks outside the cable box for broadcasts 3 Former Charleston National employees gather for a reunion 4 Deer in 8 WV counties found dead from EHD 5 Vietnam veteran builds prosthetics in war zones W.Va. Medicaid decision was not quick, easy, officials say Previous Story Dozens of emergency vehicles to take part in annual parade Next Story


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European stock markets have risen but the euro has dipped against the dollar on Tuesday as investors cautiously welcomed a bailout deal for Greece that eased fears over a bankruptcy for the indebted eurozone country.
London's FTSE 100 index of leading companies rose 0.22 per cent to close at 5799.71 points, Frankfurt's DAX 30 climbed 0.55 per cent to 7332.33 points, and in Paris the CAC 40 edged up 0.03 per cent to 3502.13 points.
"European equities are trading moderately higher as overnight, EU finance ministers finally managed to agree to a compromise" on Greece, said ETX Capital trader Markus Huber.
"While a watered down deal was more or less expected and therefore is already to a huge degree priced into share prices, at the same time this agreement/compromise does remove a substantial amount of uncertainty" regarding Greece's membership of the eurozone, he added.
Borrowing prices for eurozone sovereigns hit by the crisis eased on the secondary debt markets with Greek benchmark bonds down to 16.249 per cent, from 16.507 per cent on Monday and Spain down to 5.520 per cent from 5.620 per cent.
US stocks were mostly unchanged on Tuesday with the Dow Jones Industrial Average flat in midday trade and the broad-market S&P 500 up 0.05 per cent, while the Nasdaq Composite gained 0.12 per cent.
Greece won breathing space on Tuesday with long-frozen eurozone loans to restart from December and a first clear admission that a chunk of the country's debt burden will eventually have to be written off.
After 13 hours of talks in Brussels, the eurozone and the International Monetary Fund agreed to unlock 43.7 billion euros ($A54.63 billion) in loans and on the need to grant significant debt relief for decades to come.
Greece must still meet a series of agreed conditions but "the decision will certainly reduce the uncertainty and strengthen confidence in Europe and in Greece," said European Central Bank President Mario Draghi who left the talks before a final press conference.
The news led to buying of bank shares, with Deutsche Bank advancing 2.32 per cent to 33.92 euros, French lender Societe Generale up 2.21 per cent to 27.02 euros and Royal Bank of Scotland jumping 3.51 per cent to 295.1 pence.
In foreign exchange deals on Tuesday, the European single currency was trading at $1.2938 compared with $1.2971 late in New York on Monday after an initial euro rally petered out.
Gold prices dipped to $US1746.25 ($A1,676.59) an ounce from $1750.50 on Monday on the London Bullion Market.
Asia-Pacific stock markets mostly finished higher on Tuesday, with Tokyo closing up 0.37 per cent and Sydney rising 0.74 per cent. Hong Kong ended flat.
"This is likely to ease a lot of the uncertainty surrounding the eurozone at the moment, however the positive reaction in the markets will be limited," said analyst Craig Erlam of Alpari UK.
"There is still the huge issue of the fiscal cliff which has become the greatest threat to the global recovery in recent months," he said.
Markets have been closely tracking progress in Washington aimed at averting the so-called fiscal cliff of spending cuts and tax hikes, which will likely send the economy into recession if it comes into effect.
The White House on Monday expressed optimism that a deal would be reached.


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LONDON Welsh have this afternoon announced tight-head prop Ben Cooper as their 25th summer signing.
Cooper, 25, rejoined Cambridge from Bedford Blues for the 2014-15 season, only for Welsh to swoop and offer him the chance of Aviva Premiership rugby.
The prop joins up with former Bedford teammate Ricky Reeves at the Oxford-based Exiles, who open their pre-season campaign at Henley Hawks on Saturday.
Latest Sport news


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Study to Investigate the Safety and Efficacy of Lithium in Volunteers With Amyotrophic Lateral Sclerosis (ALS)
- Full Text View
- Tabular View
- Study Results
- Disclaimer
- How to Read a Study Record
|Amyotrophic Lateral Sclerosis
|Drug: Lithium Carbonate Drug: Riluzole Drug: placebo
|Phase 2 Phase 3
|Study Type:
|Study Design:
|Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
|Official Title:
|A Multicenter, Double-Blind, Placebo-Controlled, Study to Investigate the Safety and Efficacy of Lithium in Combination With Riluzole in Volunteers With Amyotrophic Lateral Sclerosis (ALS)
- Amyotrophic Lateral Sclerosis Functional Rating Scale - Revised Questionnaire (ALSFRS-R) [ Time Frame: 9 months: Baseline to study termination (January 2009 - October 2009) ]ALSFRS-R is a self-administered ordinal rating scale questionnaire (rating 0-4 for each question,4 is most functional,0-48 total)of 12 functional activities. The most functional total score is 48. ALSFRS-R done at baseline and weeks 4, 8, 12, 16, 20, 24, 28, 32, 36, 40, 44, 48 & 52, dependent on enrollment duration. Number of subjects who failed by treatment group was evaluated. Failure was defined as 6-point drop in ALSFRS-R or death from baseline.
- Amyotrophic Lateral Sclerosis Functional Rating Scale - Revised Questionnaire(ALSFRS-R) [ Time Frame: 9 months: Baseline to study termination (January 2009 - October 2009) ]ALSFRS-R is a self-administered ordinal rating scale questionnaire (rating 0-4 for each question,4 is most functional,0-48 total)of 12 functional activities. The most functional total score is 48. ALSFRS-R done at baseline and weeks 4, 8, 12, 16, 20, 24, 28, 32, 36, 40, 44, 48 & 52, dependent on enrollment duration. Secondary efficacy was evaluated by comparing the mean rate of decline of ALSFRS-R score by treatment group.
- Vital Capacity (VC) (Percent of Predicted Normal) [ Time Frame: 9 months: Baseline to study termination (January 2009- October 2009) ]Secondary efficacy was measured by comparing the rate of decline of mean VC by treatment group.
|Study Start Date:
|January 2009
|Study Completion Date:
|October 2009
|Primary Completion Date:
|October 2009 (Final data collection date for primary outcome measure)
|Assigned Interventions
Active Comparator: 1
Participants randomized to lithium/riluzole (randomization is 1:1 lithium/riluzole to placebo/riluzole, i.e., participants have an equal chance of getting randomized to lithium vs. placebo).
Drug: Lithium Carbonate
Participants will receive capsules that contain 150 milligrams (mg) lithium carbonate. Participants will be randomized to lithium/riluzole or placebo/riluzole and treated for 52 weeks. Participants originally randomized to placebo who fail (progress) will crossover to lithium for the remainder of the trial.Drug: Riluzole
All participants enrolled in this study will be taking a stable dose of riluzole 50 milligrams (mg) by mouth (PO) twice per day (BID) for at least 30 days prior to screening.
Placebo Comparator: 2
Participants randomized to placebo/riluzole (randomization is 1:1 lithium/riluzole to placebo/riluzole, i.e., participants have an equal chance of getting randomized to lithium vs. placebo).
Drug: Riluzole
All participants enrolled in this study will be taking a stable dose of riluzole 50 milligrams (mg) by mouth (PO) twice per day (BID) for at least 30 days prior to screening.Drug: placebo
an inactive substance
Detailed Description:
Amyotrophic lateral sclerosis (ALS) is a rare, neurodegenerative disorder that results in progressive wasting and paralysis of voluntary muscles.
In this double blind, randomized, placebo-controlled clinical trial, researchers will evaluate the safety and effectiveness of the drug lithium given in combination with riluzole, a drug commonly used to treat ALS, compared to a placebo given in combination with riluzole.
Approximately 250 participants will be recruited from multiple centers, in the US and Canada, that belong to the Northeast ALS Consortium (NEALS) and the Canadian ALS Clinical Trials and Research Network (CALS). Enrollment will occur in stages. Initially 84 participants will be enrolled in the trial. An interim analysis using available data will occur after the 84th participant is enrolled. During this time, the Data and Safety Monitoring Board (DSMB) appointed by the National Institutes of Health (NIH) may decide to stop the trial for efficacy or futility reasons or to stop enrollment and request that follow-up continue with the 84 participants already enrolled in the trial, or the DSMB may decide to continue enrollment.
Participants will be randomized to one of two arms of the study. Arm one will receive lithium and riluzole. Arm two will receive riluzole and placebo (an inactive substance). All participants will be receiving riluzole. After screening and randomization, participants will be followed every 4 weeks for the first 12 weeks. Subsequent in-person visits will occur every 8 weeks with a final visit at week 52. Between in-person visits, telephone interviews will take place every 4 weeks to administer the Amyotropic Lateral Sclerosis Functional Rating Scale—Revised (ALSFRS-R) questionnaire. A follow-up telephone interview will occur at week 56 (off study medication) to review adverse events. The primary outcome measure is disease progression as measured by the ALSFRS-R questionnaire. Participants randomized to placebo whose disease progresses will be crossed over to lithium for the remaining period of the study (up to 52 weeks total).
Duration of the study for participants is 56 weeks which includes 52 weeks of treatment and a followup telephone interview at week 56.
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Familial or sporadic ALS
- Participants diagnosed with laboratory supported probable, clinically possible, probable or definite ALS according to the World Federation of Neurology Revised El Escorial criteria
- Disease duration from symptom onset no greater than 36 months at the Screening Visit
- Age 18 years or older
- Capable of providing informed consent and complying with trial procedures
- On a stable dose of riluzole 50 milligrams (mg) twice per day(bid) for at least 30 days prior to screening
- Vital capacity (VC) equal to or more than 60% predicted normal value for gender, height and age at the Screening Visit
- Creatinine <1.5 milligrams per deciliter (mg/dl) [133 micromoles per liter (umol/L]
- Participants maintained on thyroid medication must be euthyroid for at least 3 months before the Screening Visit.
- Participants with psoriasis must have inactive disease for at least 30 days before the Screening Visit.
- Women must not be able to become pregnant (e.g., post menopausal for at least one year, surgically sterile, or practicing adequate birth control methods) for the duration of the study. Women of childbearing potential must have a negative serum pregnancy test at the Screening Visit and be non-lactating.
- Geographic accessibility to the study site
Exclusion Criteria:
- History of known sensitivity or intolerability to lithium or to any other related compound
- Prior exposure to lithium within 90 days of the Screening Visit
- Exposure to any investigational agent within 30 days of the Screening Visit
- Participants who are malnourished, dehydrated or on a sodium-free diet will be excluded due to the potential side effects of lithium carbonate
- Use of digoxin or iodide salts [e.g. calcium iodide, hydrogen iodide (hydriodic acid), iodide, iodinated glycerol (Organidin), iodine, potassium iodide (SSKI), and sodium iodide supplementation beyond table salt]
- Presence of any of the following clinical conditions: Substance abuse within the past year; Unstable cardiac, pulmonary, renal, hepatic, endocrine, hematologic, or active malignancy or infectious disease; autoimmune deficiency syndrome (AIDS) or AIDS-related complex; Clinically active psoriasis within 30 days of the Screening Visit; Unstable psychiatric illness defined as psychosis (hallucinations or delusions) or untreated major depression within 90 days of the Screening Visit; Screening serum creatinine greater than or equal to 1.5 mg/dL (133 umol/L), thyroid stimulating hormone (TSH) > 20% above the upper limit; Presence of any clinically significant conduction abnormalities on electrocardiogram (ECG); or Lactating or have a positive serum pregnancy test at the Screening Visit.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00818389
Show 37 Study Locations
|Principal Investigator:
|Merit Cudkowicz, MD, MSc
|Massachusetts General Hospital
|Principal Investigator:
|Swati Aggarwal, MD
|Massachusetts General Hospital
|Principal Investigator:
|Lorne Zinman, MD, MSc, FRCPC
|Sunnybrook Health Sciences Center, Univ. of Toronto, Toronto, CA
|Principal Investigator:
|Jinsy Andrews, MD
|Columbia University, New York, NY
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
|Responsible Party:
|Merit Cudkowicz, MD, MSc, Co-Director, Neurology Clinical Trials Unit, Massachusetts General Hospital
|ClinicalTrials.gov Identifier:
|NCT00818389 History of Changes
|Other Study ID Numbers:
U01NS049640 ( U.S. NIH Grant/Contract )
3U01NS049640-04S1 ( U.S. NIH Grant/Contract )
|Study First Received:
|January 6, 2009
|Results First Received:
|May 10, 2010
|Last Updated:
|March 18, 2011
Keywords provided by Massachusetts General Hospital:
Amyotrophic lateral sclerosis
Lou Gehrig's disease
Additional relevant MeSH terms:
Motor Neuron Disease
Amyotrophic Lateral Sclerosis
Pathologic Processes
Neurodegenerative Diseases
Nervous System Diseases
Neuromuscular Diseases
Spinal Cord Diseases
Central Nervous System Diseases
TDP-43 Proteinopathies
Proteostasis Deficiencies
Metabolic Diseases
Lithium Carbonate
Antidepressive Agents
Psychotropic Drugs
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Antimanic Agents
Tranquilizing Agents
Central Nervous System Depressants
Physiological Effects of Drugs
Excitatory Amino Acid Antagonists
Excitatory Amino Acid Agents
Neurotransmitter Agents
Neuroprotective Agents
Protective Agents
ClinicalTrials.gov processed this record on September 21, 2017


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- Minimal paths on ordered graphs (1999)
- To present the decision maker's (DM) preferences in multicriteria decision problems as a partially ordered set is an effective method to catch the DM's purpose and avoid misleading results. Since our paper is focused on minimal path problems, we regard the ordered set of edges (E,=). Minimal paths are defined in repect to power-ordered sets which provides an essential tool to solve such problems. An algorithm to detect minimal paths on a multicriteria minimal path problem is presented
- Hyperquasivarieties (2003)
- We consider the notion of hyper-quasi-identities and hyperquasivarieties, as a common generalization of the concept of quasi-identity and quasivariety invented by A.I. Mal'cev, cf. [10], cf. [5] and hypervariety invented by the authors in [6].
- Clones preserving a quasi-order (1999)
- It is proved that if a finite non-trivial quasi-order is nota linear order then there exist continuum many clones, whichconsist of functions preserving the quasi-order and containall unary functions with this property. It is shown that, fora linear order on a three-element set, there are only 7 suchclones
- Locally Maximal Clones II (1999)
- Vorlesung Logik (2000)
- Presentation of power-ordered sets (2000)
- Power-ordered sets are not always lattices. In the case of distributive lattices we give a description by disjoint of chains. Finite power-ordered sets have a polarity. We introduct the leveled lattices and show examples with trivial tolerance. Finally we give a list of Hasse diagrams of power-ordered sets.
- Logic (2001)
- Handwritten digitized script to Prof. Schweigert's lecture "Logic"
- Universal Algebra (2004)
- Handwritten digitized script to Prof. Schweigert's lecture "Universal Algebra"
- Diskrete Mathematik (2005)
- Vorlesungsskript Diskrete Mathematik


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Well this is where I originally meant to post my videos but I accidentally posted under the Technique section.
Here's a slow-motion video of me throwing 4 (Pathetic) drives. 2 Wizards, a Teebird and a Destroyer.
Watching it myself I can already see some things I blatantly did wrong, like on drive #1 released too early, final 3rd of the x step has my feet too wide apart and unbalanced. Looking at all four drives I think I need to slow down and shorten my x-step, and accelerate later on the pull through. These drives were a little below average for me, usually throw this hole better.
This is the video I posted yesterday, just a collection of Wizard drives with the holes listed (Distances are on DGCR). Not quite as boring as the first video
http://www.youtube.com/watch?v=kx9w6cOs ... r_embedded


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BLACKBURN Rovers boss Gary Bowyer paid tribute to his side's 'magnificent' supporters on the 25th anniversary of the Hillsborough disaster.
Bowyer was furious at his players for letting a two-goal lead slip in the 3-3 draw at Sheffield Wednesday on Saturday.
But he had nothing but praise for both sets of fans and clubs for their conduct in a moving pre-match ceremony to remember the 96 Liverpool supporters who lost their lives at Hillsborough during an FA Cup semi-final tie against Nottingham Forest on April 15, 1989.
Bowyer said: "Our supporters were magnificent and, having the paid respect that they did for the 96 magnificently well, they should have been going away celebrating the win.
"We haven't been able to provide them with that and that is majorly disappointing.
"Sheffield Wednesday and their supporters need credit for the way it has gone too. I think it was marked properly."
After an impeccably observed minute's silence Bowyer, who was in the Nottingham Forest end as a fan on that fateful day at Hillsborough 25 years ago, joined his Owls counterpart Stuart Gray in picking up the wreaths they had placed in the centre circle and laid them in front of the Leppings Lane end, where 96 died and hundreds others were injured.
Wednesday boss Gray added: "No father, no mother, or no son or daughter should lose anybody at a football game.
"It was just a sad, sad occasion, what happened 25 years ago.
"But I think the players played their part, the fans played their part and both clubs played their part today."


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Being first in line has its advantages, even for wind turbines, which are propelled by comparatively smooth wind flow that helps them produce near-optimal power at varying wind speeds.
But in the first row's wake, turbulence increases and air speed drops, cutting turbine power production and even causing excessive wear on turbines. How that turbulence dissipates is not fully understood.
To start filling that gap in understanding, researchers at the University of Colorado Boulder have performed the first direct measurements of dissipation rates of wind turbines in real-world conditions. Wake turbulence might dissipate faster than commonly thought and in ways existing weather models do not reflect, their study suggests.
Julie Lundquist, CU-Boulder assistant professor of atmospheric and oceanic sciences, presented these findings during a scientific session on weather-driven renewable energy at the fall meeting of the American Geophysical Union in San Francisco.
"We care about wakes not just because they're beautiful, but studying them will help us understand how to produce more power and minimize turbine maintenance costs," Lundquist said.
Before this study, turbulence dissipation rates had been directly measured only in wind tunnels. Estimates of dissipation rates from scanning lidar have also been carried out at this location in a previous study in which Lundquist's research group collaborated with CU's Cooperative Institute for Research in Environmental Sciences and the National Oceanic and Atmospheric Administration's Earth Systems Research Laboratory.
That study was just published in the Journal of Atmospheric and Oceanic Technology.
"Although wind-tunnel measurements of wind speed can represent what happens in the real atmosphere, scaling wind-tunnel measurements of turbulence is more difficult," she added. "We need to compare real-world measurements to wind-tunnel measurements to understand how that scaling works for turbulence."


text:
Bridal Spa Tips
The complete bridal spa guide from SpaFinder. Everything you need to prepare for your big day. Before you say "I do," commit to SpaFinder's complete bridal spa guide to help you prepare for your big day.
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The 'mane' event on your big day often begins as your bridal party, flower girls, and family join you in the salon for some all out dolling-up (and major bonding time!). Before you say "I do," check out SpaFinder's tips on planning your perfect wedding hairstyle. Read more


text: In a type 2 diabetes study, researchers measured antioxidant levels in the diets of 1,018 men and women, aged 38 to 52. Some did not have diabetes, some were pre-diabetic with elevated fasting blood sugar levels, and some had type 2 diabetes. In all three groups, as antioxidants in the diet increased, average blood sugar levels decreased. Differences in age, sex or amount of physical activity did not change the results, although antioxidants did not change blood sugar levels in those who were obese. Doctors believe that antioxidants can lower the oxidative stress that promotes diabetes and may also help pancreatic cells produce insulin.


text:
In this week's webinar, we'll show you some of the new features coming to Excel 2013. You can try them out right now during the free Customer Preview.
What you will learn at Tuesday's webinar:
- How to visualize your data quickly
- New, easy ways to reformat and rearrange your data
- How to do a Pivot Table (without knowing about Pivot Tables)
- New ways to share data
References for this webinar:
- Download the free customer preview site: office.com/preview
- Previous webinar about the benefits of an Office subscription
- About the Office 365 Home Premium Preview
- Getting Started with the new Office
- Excel 2013 preview article
- In-depth look at Flash Fill (Excel blog)
Go to http://aka.ms/offweb for more information on how to join the series.
–Doug Thomas


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Jason Reed/Reuters/Landov
Michelle Obama's look won't be the only fashion statement to live on past last week's Inauguration. Selling like hotcakes are $179 versions of Aretha Franklin's distinctive hat with its Swarovski rhinestone-rimmed bow that the Queen of Soul wore to sing "America" at the swearing-in ceremony. The hat's designer, Luke Song of Detroit's Mr. Song Millinery, tells the
Los Angeles Times
he's sold thousands since its debut on national TV. While Aretha's hat was a customized version, Song will be responding to demand by producing a collection of 12 hats in a variety of colors and bow sizes, priced from $150-$220. The Aretha-inspired collection will be shown during February's Women's Wear in Nevada trade show in Las Vegas. The company sells its hats in over 500 U.S. stores. and while they usually doesn't name their toppers, this collection will be named after the singer herself. If you're dying for a hat like Aretha's, click over to mrsongmillinery.com for contact info. Tell us: Would you wear a hat like Aretha's?


text:
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text: Search essays and transcripts accompanying our films. You may search using up to six terms or as few as one. Each term may search essay titles, essay summaries or the full text of the essay. You may combine all the terms using AND to narrow down your search or choose OR to widen your search. Each term searches for the exact phrase, so if you enter "kewpie dolls" you will find only those items that match, not texts containing either "kewpie" or "dolls." To search for "kewpie AND dolls" you need to set two terms, one for "kewpie" and one for "dolls" and check AND search. This allows advanced searchers to precisely specify their search.


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very very good
Used the club on several rounds on different courses and it's all I expected performance wise. It fits the bill for me during sand work or chipping around the green. My only dissatisfaction with the club is,the copper is beginning to wear off where I strike the ball.
bought the 50.10 and the 54.11, haven't gotten them yet from GG, but i tried em out at a local shop and i really like the feel. can't go wrong with these. look great, too.
Use this club every outing. Came is great condition.


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Ukiah Daily Journal
The image of a tired, homesick soldier gently plucking his guitar after a long day in a war-torn foreign country may very well embody the mission behind the annual Guitars for Troops event, presented by Rotary of Ukiah.
The event, now in its second year locally, brought the community together on Saturday for a jam-packed show consisting of five of the area's best bands: Double Standyrd, Waylon and the Wild Cats, McKenna Faith, Sudden Turn and the Funky Dozen, topped off with Si Ramos' famous barbecue - all to benefit veterans services.
"Guitars for the Troops came about from a desire to provide musical therapy to our military troops serving overseas and recuperating from injuries. The great thing about playing a musical instrument is it provides therapy to the player and also to the listener. As long as the instrument can be played, it will provide music for as few as one and as many as thousands. These guitars are made for years of use, which means they will be played now and well into the future," said Gordon Close, who founded Guitars for the Troops.
The complete guitar set includes a Harvest handcrafted acoustic guitar made to withstand the rigors of tough environments and rough handling, a padded case, extra guitar strings, shoulder strap and a beginner lesson book with CD. It is valued at over $400, but through an agreement with Harvest Guitars, costs only $150 when purchased through the Guitars for the Troops Program.
Last year's inaugural event was inspired by Todd and Shari Schapmire's trip to New Orleans where they stumbled upon a pamphlet at an international Rotary conference prompting them to help create a local Guitars for Troops event.
"Wow, that's really cool," thought Shari, Ukiah Rotary president, who spent the trip home discussing the possibilities with her husband, Todd, a Ukiah High School employee and local musician. "Military people don't have a lot to do on their days off, how cool for them to have a guitar to play," said Shari previously.
With all of the bands volunteering to perform for free, 100 percent of the proceeds from the 2011 Guitars for Troops event was divvied between several local veterans organizations, in addition to providing 35 high quality guitar sets to active military and veterans.
Local veterans services received more than $4,000, including $2,000 to the local Veterans Affairs to assist with providing funds to needy veterans for necessities such as food or gas. The Mendocino College Veterans Center was given a complete guitar set and $2,000, as well as $250 donated through the Community Foundation to assist previously homeless vets with funds to purchase household appliances once they receive housing.
UHS graduate and retired Marine Corps major, Patrick Keplinger, now active in the Wounded Warriors Program, will be distributing 10 of the 35 guitars; an additional five guitars went to "Rock for Vets," a musical therapy program sponsored by the Long Beach Veterans Hospital with a long range goal of developing the program at every military hospital, and active military serving in Afghanistan received 10 guitars.
The remaining 10 instruments were handed to active military and veterans with ties to Ukiah: Rodney Jones, Jeff Prindle, Jessie Yoast, Chris Bivens, Tyler Fox, Chros Pischi, Tyler Tessmer, Chris Ward, Jaime Herrera Vega and Dustin Britton.
Private First Class Jaime Herrera Vega and Private Dustin Britton, both Marine Corps, were awarded their guitars at the Oct. 23 Rotary meeting, and although the two aren't currently musicians, both said they were excited to learn.
"I'm gonna take the guitar set back to Carolina and learn how to play. This is awesome to show such support, I'm thrilled," said Jaime, whose parents Jaime Sr. and Maria Herrera Vega were in attendance to see him get his guitar. "I couldn't leave them out of it," smiled Jaime.
"It's a lot of worries," said Jaime Sr., adding, "I have another son, Luis, who has been to Afghanistan three times."
Dustin, son of Mike and Tammie Britton of Ukiah, said the first song he would try and tackle was "Sweet Child of Mine," by Guns and Roses because Slash was such a great guitarist, and "It's a classic."
Upon receiving his new guitar set Dustin said, "I'm overwhelmed ... it's a great feeling. I've accomplished things most people wouldn't dare to do, but I'm not used to all these congrats."
Both gentlemen were nominated to receive guitars by Marine Corps Staff Sgt. Marcus R. Galvan, who Todd credits with being a huge help in navigating military waters, lauding Galvan with being his "right hand when it comes to the armed forces."
About handing out the guitar sets Todd says, "They tell me thank you' and I turn around and say, No, thank you!'"
Guitars for Troops presented by the Rotary Clubs of Ukiah is sponsored by: The Ukiah Daily Journal, K-Wine 94.5 FM/Max 93.5 FM, Brandon Knight Visual Creations, Thurston's Auto, Canteen Service, the Ukiah Police Department, Savings Bank of Mendocino County, Walmart, Carl's Junior, Mendocino Brewing Co., Raleys, McCarty's Auto Body, Ken Fowler Motors, Remax Full Spectrum, Petersen Law Offices, Lee Kraemer Real Estate, Dave Hull-Farmers Insurance, Testa Vineyards, Taco Bell, Realty World/Selzer Realty, Liqa-Tech, Mendocino Vineyards, Mendo Mill and Lumber, Mendo-Lake Credit Union, The Deputy Sheriff's Assoc., Charles Kelly-LPL Financial, Eagle Distributing, The Office and Stephen Pasternak, DDS.
Those who would like to donate directly to the Guitars for the Troops program can send payments marked "Guitars for the Troops" to the Ukiah Rotary Club, 704 N. State St., Ukiah, CA 95482.
Kelly Hancock can be reached at firstname.lastname@example.com, 468-3520 and on Twitter @udjKelly.


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I've been talking here and there about the corner of our room where we'll put the baby's things. I almost have it finished now. Crib is built, lights are hung, bedding washed. But I'm waiting one more small item before I share her space. You can see peeks of it on my Instagram stream though!
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thank you for your comments!
if you have any questions please email me via the 'contact' link.


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Bird couples nestle together in a stylized forest.
Basic Print Size: 16 " x 20"
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Your personalized order is not complete without a Ketubah Information Form
Our standard turnaround for ketubahs is 3 weeks, please choose 'rush' if you need it sooner.
For Canadian shipments, the option is the same as US 2nd day.


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Burton Honey-Baked Hammock
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- Lifetime Warranty


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... it will only upset you.
http://achesoncreations.com/index.php?p ... 1&Itemid=1
carvel2 wrote:I looked
BUT I'm not downhearted
Mine cost a fraction of that .....but it is a very nice piece of kit!!!!
If money were no object.......
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text:
....but there are different interpretations of Shentong, as well. Brunnholzl walks you through the varieties....
Which book? His stuf is a "only as much as necessary" read for me.
As a footnote, I am currently under the impression (subject to change by new information)
That sutra Mahamudra leans towards Rongtong, and tantric Mahamudra leans to Shentong. But as Cone said, in Kagyuland quite often the entire subject is simply not even brought up for people devoting themselves to actual practice.


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"I would hear these skinny girls talk in the locker room about how they were getting fat," says Delia, now 25. "And I'd think, 'If they're fat, then what am I?' "
But Delia doesn't regret her cross country career. And running is now one of the things that helps keep those old impulses in check.
"This story," she says, "has a happy ending."
Delia, who describes herself as "a really angst-y teen" with good grades and dyed hair, started running and dieting at 15 after a doctor warned she might be developing a weight problem. She loved the way jogging seemed to make the pounds just melt off her body.
She joined her Herndon, Va., high school's cross country team as a junior, in part because her boyfriend was going out for the team.
It was fun to hang out with kids who were more popular than her usual crowd, and she was learning a lot about running. But fretting over races and worrying that her body, even at its thinnest, didn't fit the narrow, flat-chested form of her teammates "sucked the joy out of running for me," she says.
Delia started throwing away her school lunches — and felt proud of herself for exerting such self control. After the season, she kept up a grueling workout schedule, feeling tense if she didn't log 6 or 7 miles a day.
"I was never, like, a skeleton, really," she says.
But she does remember trying on a dress for a dance that fit perfectly at the store, only to get looser and looser as the dance approached.
"Hmm, that's weird," she recalls her mom saying as she realized she'd have to take in the dress. But by the day of the dance, it had somehow gotten loose again.
By the time she moved on to James Madison University, Delia was beginning to realize that putting too much emphasis on numbers — times, mileage, calories — "just manifests itself in a really negative way for me."
Realizing her school offered therapy services, she decided to get help, figuring "it would be someone I could talk to so I wouldn't get on my friends' nerves."
And she gave running a rest.
Delia cites a book her therapist gave her, "The Body Project," by Joan Jacobs Brumberg, as helping her learn to appreciate the variety of body types instead of shooting for some unattainable ideal.
Eventually she returned to running with a whole new attitude. Instead of causing stress, it now helps relieve hers.
"My relationship with running is a lot better now," she says. "I try to be kind to myself when I'm running. I don't wear a watch. It's OK if I need to walk… It's definitely about the experience, and not the time. It's a mental release."
As for her eating disorder, she feels like she has that under control. A vegetarian since age 18, she now loves to cook, experimenting with organic ingredients.
"I figure I may eat too much sometimes, but at least it's healthy food," she says.
Still, she's aware of her triggers. Sometimes on a particularly stressful day she'll realize it's 5 p.m. and she hasn't eaten anything yet. She doesn't freak. She just reminds herself to eat something.
"I think it (the eating disorder) will always be a part of my life," she says.
But so is running. Lately she's even started to think of it as a form of transportation, dropping off her rent check or stopping by to see friends.
No races, though. And she limits her runs to 4 miles to avoid getting obsessed.
"I have no idea what my mile time is," she says.
And that's just the way she likes it.


text: If you are on a budget, Winsome end tables are perfect. The company offers a variety of end tables that come with different features. Whether you are looking for end tables with shelves or end tables with drawers and cabinets, you will find them from Winsome. If you are not looking for anything extravagant, Winsome end tables come in basic and clean designs. They are available in popular finishes such as black, white, espresso, walnut, and honey. They also come in square, round, and rectangular shapes. We also carry Winsome coffee tables. Why not pair a Winsome end table with one today? Read More


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I Like to ActLanguage brain teasers are those that involve the English language. You need to think about and manipulate words and letters.
I like to act but not to pretend.
I like to hop but not to jump.
I like to bet but not to gamble.
I like to begin but not to start.
What kinds of things do I like to do?
AnswerI like to do things in which the letters of the word are in alphabetical order.
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See another brain teaser just like this one...
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text:
Connolly Receives Affordable Housing Award
Fairfax County Office of Public
12000 Government Center Parkway, Suite 551
Fairfax, VA 22035-0065
Oct. 25, 2005
Gerald E. Connolly Receives AHOME Preservation Award
Fairfax County Board of Supervisors Chairman Gerald E. Connolly has received the AHOME Preservation Award for his leadership, courage and innovation in preserving affordable housing in the Fairfax/Falls Church area.
Connolly was presented the award at a ceremony on Oct. 19 by AHOME, or Affordable Housing Opportunity Means Everyone, a nonprofit coalition of community businesses, developers, unions, resident organizations and other nonprofit public service groups interested in finding ways to meet community needs for affordable housing.
"Receiving this award from AHOME is a great honor, and it reflects the county's commitment to preserving affordable housing units to meet the needs of our residents," said Connolly. "This area is one of the Board of Supervisors' six priorities outlined last year, with a goal of preserving 1,000 units by 2008. We are well ahead of schedule in meeting that goal."
Connolly was recognized at the ceremony for his vision and determination to preserve affordable housing in Northern Virginia, and for creating and implementing the One Penny for Housing program, which has preserved nearly 600 affordable housing units in Fairfax County.
"When we were deciding who to give this award to, there was only one person that came to mind: Gerald Connolly," said Jerry Hopkins, AHOME president. "His leadership on this issue was a beacon to everyone, and Fairfax County is now a front-runner in preserving affordable housing units."
To request this information in an alternate format, call the Office of Public Affairs at 703-324-3187, TTY 711.


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Dr. Tsunehiro Yasuda MD
- Nuclear Medicine Boston, MA
Patient Reviews
Reviews reflect patients' level of satisfaction with the care they received from this provider. Dr. Tsunehiro Yasuda does not yet have any reviews.
Dr. Tsunehiro Yasuda, MD is a Doctor primarily located in Boston, MA. He has 48 years of experience. His specialties include Nuclear Medicine. Dr. Yasuda is affiliated with Boston: Massachusetts General Hospital, Mass General Hospital and Massachusetts General Hospital. He speaks English.
Find out the languages this doctor/ or staff may speak.
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Learn where this doctor attended medical school.
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Specialties & Expertise
Dr. Tsunehiro Yasuda has the following 2 areas of expertise, 1 specialty and 1 board certification.
Nuclear Medicine
Nuclear medicine specialists are doctors who have extensive training in the use of nuclear substances, like radiation, to diagnose and treat certain illnesses.
These specialists perform diagnostic tests in which a small amount of a radioactive substance is injected into a vein, inhaled or taken orally by the patient. The radioactive substance then enables the nuclear medicine specialist to use a scanner to detect the radiation level in the part of the body being examined in order to create an image of it with a computer. The images tell the physician whether there are abnormal changes in metabolism which indicate whether a disease or injury is present. These tests are often used to detect cancer.
In addition to detecting cancer, substances like radioactive iodine can be either injected into the blood stream or taken orally to fight cancer and other diseases. After being ingested, the substance is absorbed by the thyroid gland and abnormal thyroid tissues are destroyed.
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text:
Please be aware that there are some commercial web sites and businesses that are deceiving applicants into believing that they are Kempinski sites or approved by Kempinski. Some companies even demand money by phone or email in order to complete the application or visa process.
Please note that Kempinski Hotels does not issue employment contracts without interviews by phone and/or in person. No candidate would ever be asked to pay out of pocket money to the company in advance or in order to secure a job. If anyone asks this in our name they are not representatives of Kempinski. Please contact the People Services department at the respective hotel directly to report such activities.


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Hi, I need to create a pattern matching program. I have successfully created one that matches a template image to a full video. Now, I need a program that updates the template image with each frame. So I would create the template on frame 1. Then on frame 2, when the program finds a spot that matches the template, it saves this image as the new template to compare to the next frame. This would continue for the full video. Does anyone have a program that does this? Or any idea where to start? I am using Labview 2010. Thank you!
Hi frog7,
It sounds like your program that 'matches a template image to a full video' would be a good place to start, unless I misunderstand what this program does. Can you post this code so that I can take a look and perhaps give you some pointers on how to adapt this code to achieve the new functionality that you need? I'm assuming that you are using the Vision Development Module for LabVIEW 2010 as in your previous posts. Also, for future reference, it would be better for you to post this question in the Machine Vision boards. Thanks!


text:
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© Fiskars Brands, Inc. Orange handled scissors are a registered trademark of Fiskars Corporation.


text:
H&M is finally tackling the online market, and plans to launch an e-commerce site in the U.S. in August.
The timing of the move for a brand synonymous with affordable fashion is opportune because it coincides with the heart of the back-to-school shopping season and sets the stage for the company to drive online sales during the holiday season.
The company, which runs an online site where consumers can browse through product offerings, is investing in IT, online sales and new brands in an effort to broaden its range. Come August, consumers will be able to purchase merchandise online, and the company stands to reach existing customers who prefer the convenience of online shopping, as well as potential new customers who don't have convenient access to one of the 268 stores the company operates in 30 states.
"There is great potential in the growing online market. We are looking forward to launching our online sales in the U.S. in August. In parallel, we are continuing our work on the global rollout of H&M's online store, with the aim of adding several new online countries during 2014," said CEO Karl-Johan Persson. Persson did not identify other countries in the company's plans for its online launch, but with a global portfolio of 2,900 stores in 49 countries, the company has plenty to choose from.
The announcement was made in conjunction with the company's release of its first half-year sales for the period ended May 31, which increased by 5% compared to the same period last year. The company also indicated the second half of the year is off to a good start as well. A successful start for the company's & Other Stories brand, as well as continued good performance by its Cos brand, have bolstered the company's sales for the month with an increase of 14% in local currencies, compared to the same period last year.
H&M Hennes & Mauritz AB operates the H&M brand as well as Cos, Monki, Weekday, Cheap Monday, & Other Stories and H&M Home.


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"Hello Mr Flair, can I help you today?."
"Are you the man!?? WOOOOO!"
"What do you mean?"
"Are you THE man?"
"I don't know, I work quite hard but I think others are more popular.
It's nothing personal it's just how the world is."
Updated 01-26-2014 at 01:51 PM by kylos
I want to begin by saying that this tragedy is, quite possibly, the most controversial and damaging event to ever occur in the wrestling industry.
You don't find many talking about what happened, and a lot of hatred still consumes those fans who either don't want to read up on the evidence, or they know the evidence, and still wish to direct their
Updated 11-04-2013 at 01:18 PM by kylos
Episode 15 - Creativity Machine
Today, I am writing to all wrestling fans. I have a message for you all.
I would usually begin with a Peter Griffin rant, where I act out Peter Griffins upset over a particular subject for comedy value. However .. my creative process is not flowing like a drunken Peter playing a piano, because I have to address
Updated 11-03-2013 at 06:04 AM by kylos
Episode 14 - If it's not broke, don't fix it!
Peter and Homer walk into a bar. After a few beers, Peter gets onto the subject of wrestling.
Peter: Hey Homer, you know what really grinds my gears??
Homer: Celebrities?
Peter: Of course, but I was going to say Impact Wrestling.
Homer: Oh, what's that?
Peter: It's
Updated 09-22-2013 at 10:17 PM by kylos
Episode 13 - Commentary Calamity
Yes, this is about wrestling commentary. I am rather perplexed at the downfall of wrestling commentary, because it was such a big part of the shows. Can you imagine watching old school wrestling with no Jesse Ventura?? What about the Attitude
Updated 08-17-2013 at 07:01 PM by kylos
Episode 12 - Vanilla Midgets
Usually I would go into a Peter Griffin style rant here, over the particular subject matter, and have some fun for the sake of having a lighthearted beginning to my blogs.
However this time I am not in the mood. This subject has somehow slipped through my thought process til just recently, after reading
Updated 08-17-2013 at 05:15 PM by kylos
"Episode 11?? I thought we finished this garbage on the last episode?"
"No Mr Griffin, we just didn't have anymore material to give you."
"What are you talking about? I could complain about wrestling all day! I demand to see the guy in charge!"
"I am the guy in charge, and you sir, are an idiot."
Chapter Two - Fantasy World
The real world is filled with good guys and bad guys. However the line between good and evil is often blurred, and it can be difficult to tell them apart, unlike the many stories we have read, watched, written, and played out in many fictional scenarios.
You have Batman vs Joker, Superman vs Lex Luthor,
Updated 03-24-2013 at 08:08 PM by Frank
Chapter One - Changing of the Guard
In this world, we often look for ways to keep ourselves amused. We want to enjoy life, and be entertained, we want to get lost in magical lands filled with diversity. We like to listen to music, and get lost in the songs. We like to play video games and truly become one with it, even if its just for a short
Updated 01-30-2013 at 03:04 AM by kylos
Peter sat down at his desk. He was overcome with emotion, he leaned forward and put his head into his folded arms. Peter began to sob as the on-air light turned to red.
Cameraman: "Mr Griffin? We are on the air."
Peter: "I don't care." *Sniff*
Camerman: "But Mr Griffin, this is you're tenth episode. It's
Updated 01-17-2013 at 01:39 AM by kylos
© 2011 eWrestlingNews, All Rights Reserved.


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TeamDrive Secure CollaborationThe TeamDrive smart client software watches folders in the file system and enables automatic synchronization,
versioning and encryption on the bases of private collaborative workspaces.
Documents, for instances office files, photos, music or videos are always accessible, even when offline.
TeamDrive enables cross platform and cross company collaboration. Simplicity, ease of use, and the highest
security standards make TeamDrive the collaboration platform of choice.
TeamDrive greatly heightens productivity whether working alone or in a group.


text:
CHARLESTON, W.Va. — West Virginia Attorney General Patrick Morrisey is warning students and parents to be cautious of potential scams when applying for scholarships.
Officials say the warning is part of a week-long effort to provide back-to-school-related consumer-protection tips with school already underway in some areas and classes starting in other areas soon.
Morrisey's office is offering tips to follow when applying for and researching scholarships, including avoiding websites that require personal information such as a Social Security number.
Students and parents also are being told to research scholarships before applying but to be wary of websites that require them to pay a fee to search and learn about scholarships.
Those who believe they've been a victim of a scholarship scam can call the Attorney General's Consumer Protection Division at 800-368-8808.


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Indy also made offseason moves to land former New York Jets safety LaRon Landry and former Arizona Cardinals corner Greg Toler, who moved east as Jerraud Powers signed with the Cardinals to go west.
But there's always room for more in the secondary, so the Colts could go with another defensive back at No.24 on Thursday night. Here are the Top 5 possibilities:A ton of mock drafts have the Colts going with Rhodes at No.24, and his strengths are obvious. He's a big corner who can also play safety. He has speed, quickness and confidence. He picked off eight passes over the last three seasons. He can play man-to-man or zone coverage. In short, he's probably the best prospect at corner behind Albama's Dee Milliner.He's been around the game his entire life, with brothers in the pros (Marcus with the Seahawks and Isaiah with the Jets). So he knows what it takes to compete at a high level. Most scouts point to his quickness and quick feet as major assets in covering wide receivers. If he has a weakness, it might be deep against the speediest of receivers, but that's a select group that occasionally might beat him. He's mature enough to be an immediate pro.Would you take a risk on Hayden? Last Nov. 6, he suffered an injury, tearing the vena cava blood vessel in his heart. Surgeons performed open-heart surgery immediately, saving his life. During his time with Houston, he returned three interceptions for touchdowns and picked off six passes. He has great speed and has worked out twice this spring. Doctors have cleared him, but he's still a tricky pick.Banks' 40 times (4.69 at combine, 4.67 at pro day) have caused some to drop his stock, even though he's a physical, aggressive, big-play corner. In four years, he picked off 15 passes. That shows a knack for the ball. It's very possible he could be picked long before No.24. But if he's there, like Vaccaro, he might be difficult for the Colts to pass up.Poyer has decent size and a knack for getting his hands on the football (seven picks in 2012, 13 in his career). If there's one asset he has that can't be quantified, it's instinct. He was converted from safety to corner, and he knows how to make life miserable for receivers in man-to-man coverage. He can deliver some hits, as his special teams work showed at Oregon State.


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A LANDLADY near Winchester whose pub closed for weeks following the floods said she couldn't have reopened were it not for all the help she was given.
Judith Evans, who runs The Crown Inn in Kings Somborne with partner, Terry Minter, said they were up to their wellies in February when water seeped up through the ground forcing them to close.
"We're not even particularly close to the stream but it came up through the floors and, before we knew it, we had six inches of water flowing around our feet," Mrs Evans said. "We've had to have new plastering, new carpets and new decoration.
"But it's been an opportunity to do something we wouldn't have done otherwise. What could be seen as a disaster has actually had a good impact on us."
The pub was closed on February 10 but now, thanks to a lot of hard work and crucial funding, the team looks set to enjoy the summer in a brand new – and water-free – environment. Despite it being closed throughout spring and having lost a sizable income during that time Mrs Evans refuses to be down trodden.
"We've been incredibly well-supported by our insurance company, the National Farmers Union, and Test Valley Borough Council," she added. "We couldn't have done it without them and we're just so pleased with all the help. The owners, Punch Taverns, have covered our rent while we've been closed so we haven't had to worry about that and we were able to access the grant for defences so we're preventing any of this happening again.
"It's been brilliant. We simply wouldn't be here if we didn't have all this help and we're looking forward to seeing all our friends and customers and hope for a long summer ahead."


text:
Michael v. Michael: A debate on how (or if) business can solve social problems
Their names may both be Michael. They may even both be professors at Harvard. But Michael Porter and Michael Sandel offer up radically different ideas on business and its potential for good in their TED Talks, both released today. While Porter suggests that businesses are in a great position to tackle social problems — because […]Continue reading


text:
NetWellness is a global, community service providing quality, unbiased health information from our partner university faculty. NetWellness is commercial-free and does not accept advertising.
Friday, September 22, 2017
Mouth Diseases
Pimple Inside Lower Lip
I have had a "pimple" inside the bottom of my lip for almost a month now. It is the same color as the rest of my inner lip, except for a very small white head at the tip. It is about the length of a pencil eraser but not nearly as thick. It does not hurt normally, but pretty often my top teeth sink into it when i close my mouth or when I am chewing. I can always feel it and it is very annoying. I read some other questions and answers about mucoeoles and blocked salivary glands, but I wanted to mention that the one inside my lip is "loose"...almost like a "skin tag" (which i do have a couple of on my neck, not sure if that is relevant/important). The other questions I read were about bumps, but mine is not just a raised bump, it is "wiggly." I hope I provided enough information and am not repeating other questions. I have a feeling it may be a blocked salivary gland or one of the other mentioned conditions, but it has been atleast a month and it won`t go away, and I`m afraid my teeth hitting it will make it worse. What can I do for it?
What you describe could be several different types of bumps, including some that were not discussed in the article "Things that go bump in the mouth" on the NetWellness website.
It could be that you initially had a mucocele that has undergone resolution together with scarring or fibrosis, leaving a firm bump of collagen or scar tissue (often called a fibroma). A bump composed of another tissue type is also possible, but nothing about your description sounds serious. Having said that, given the size and length of time this bump has persisted, it is unlikely to resolve (go away, smooth out) on its own.
I recommend you get an appointment to see an oral and maxillofacial surgeon to examine this "pimple" and, possibly, to have it removed (a minor surgery called excisional biopsy) and sent to a laboratory for processing and diagnosis. In this way, you not only get rid of the bump, but you (and the oral surgeon) find out exactly what it was and whether or not any other treatment would be necessary. Good luck!
John R Kalmar, DMD, PhD
Clinical Professor of Pathology
College of Dentistry
The Ohio State University


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We battled to the bitter end, Ruff said. We could have easily won the game. We skated better than they did in the third period, although they might have been just trying to preserve the one point, which was important to them. Sometimes you look over and they were not taking a lot of chances. They were maybe just trying to get it to overtime to get the extra point.
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