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RECIPES: Recipe Details
Viva La France!! Burgers
This burger is French food at it's essence. The burger itself is very simple and pure: ground chuck, shallot, rosemary, fleur de sel, and freshly ground black pepper. Top that with some lardons (a type of French bacon—or you can use diced pancetta as a replacement) and you really are getting somewhere. Then you have a Tarragon Dijon mayonnaise which has many components that France is famous for such as Dijon mustard, tarragon, and some champagne vinegar. Of course you also need a cheese and I chose brie as an extremely delicious, creamy French cheese that would perfectly complement all of the flavors in this burger. Of course you need some greens so I went with baby arugula, which is a popular French lettuce. Finish it all off by putting it on a buttery, toasted brioche bun and I think that you really have many of the great tastes of France all coming together into one truly delicious burger. Viva La France!!
3/4 cup mayonnaise
1/4 cup Dijon mustard
1 clove garlic, finely minced
2 tablespoons champagne vinegar
1 1/2 tablespoons fresh tarragon leaves, finely chopped
8 ounces lardons (or 8 ounces pancetta, cut into 1/4-inch dice)
2 pounds ground chuck
1 large shallot, finely minced
2 teaspoons fresh rosemary leaves, finely chopped
2 teaspoons fleur de sel
1/4 teaspoon freshly ground black pepper
Vegetable oil, for brushing on the grill rack
6 brioche buns, sliced lengthwise
6 ounces brie cheese
3 ounces baby arugula
Prepare a medium-hot fire in a charcoal grill with a cover, or preheat a gas grill to medium-high.
To make Tarragon Dijon Mayonnaise, in a small bowl combine mayonnaise, Dijon mustard, garlic, champagne vinegar, and tarragon; mix until well combined. Refrigerate until serving.
Heat a large fireproof non-stick skillet on the grill. Add lardons (or pancetta) and cook over medium-high heat until crispy, about 5 minutes. Drain on paper towels.
To make the patties, combine the beef, shallot, rosemary, salt and pepper in a large bowl. Handling the meat as little as possible to avoid compacting it, mix well. Divide the mixture into 6 equal portions and form the portions into patties to fit the brioche buns.
Brush the grill rack with vegetable oil. Place the patties on the rack, cover, and cook, turning once, just until done, about 4 minutes on each side for medium-rare. During the last few minutes of cooking, spread equal amounts of brie cheese on top of the burgers and place the brioche buns, cut side down, on the outer edges of the rack to toast lightly.
To assemble the burgers, spread a generous amount of Tarragon Dijon Mayonnaise on the cut side of the buns. On each bun bottom, place equal amounts of arugula, a cheese-topped patty, and an equal amount of lardons. Add brioche bun tops and serve.


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A friend of the family of Warminster boy Sean Turner will run the Bath Half-Marathon in his memory on Sunday for the charity Little Hearts Matter.
Matt Porch, 20, met Sean through his mum Janet, who works as a teaching assistant at Minster Primary School, which the four-year-old attended.
Sean died in 2012 from a brain haemorrhage at Bristol Children's Hospital after undergoing heart surgery.
Mr Porch was intending to do the run last year, but damaged his anterior cruciate ligament while playing for Warminster Rugby Club, and had to have surgery.
The former Kingdown School pupil was determined to get himself fit again to run this year and is now aiming to finish in 2hrs 10mins.
Mr Porch, who is an apprentice accountant for a company in Bath, said: "When I found out I couldn't race last year, I set myself the challenge of doing it again this year as I was determined to do it for Sean.
"The injury was pretty bad and it has been challenging as I had to get my knee back to where it was before, but it has all been worth it.
"It's quite personal for me as my mum was a teaching assistant in Sean's class.
"I went into the class and met Sean a few times, so it was really upsetting when I heard about what happened as I saw what he was like.
"My mum also visited him a lot while he was in hospital.
"I know that Little Hearts Matter is not a big charity and it needs as much support as possible, so it would be really good to raise a lot of money. I like raising money for charity, but this is more personal."
Mr Porch, of The Teasels, Warminster, previously ran the half-marathon in 2012 for Macmillan and has already raised about £300 for Little Hearts Matter, but is now aiming to top the £500 mark.
Little Hearts Matter offers support and information, and raises awareness of children born with heart problems.
Sean's mother Yolanda said: "We are really happy that Matt is doing it and it means a lot to us that he is doing it in Sean's memory.
"We know it's been quite an uphill battle for him after his injury and we will be there to support him."
To donate, visit www.justgiving.com/Matthew-Porch

subset: commoncrawl


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Hey all,
I was in the body gear forum researching new shoes when I read a thread that got me thinking. I have worn out my old merrils by wearing a hole on the right side of my left shoe beside my big toe. I throw RHBH and I always thought that was just where my foot pivots and didnt give much thought about it. However, when I look at other peoples shoes, I seldom see wear in the same place and it sounded from one guy talking about the other foot throwing sidearm that I may have a case of toe drag. Is this more the case, or is this a normal place to wear out a shoe? If I am not getting a correct push off, what can I do to fix it? I just dont want to go drop some money on a nice pair of shoes again if I am going to blow them out on the side of the toe again. Thanks!


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Two homes have been destroyed and two people injured in a bushfire in central Victoria as the state also battles fires in its north and southwest.
Residents of the town of Snake Valley, about 30km from Ballarat, say two homes were burnt down on Tuesday.
"We have lost a couple of homes," a man, who did not want to be named, told AAP from the Snake Valley Hotel.
"I can see it from the hotel with the smoke four to five kilometres away."
The grassfire has grown to about 500 hectares in size and was bearing down on the farming community of Carngham where most of the 400 residents have been evacuated.
A father and son, aged in their 50s and 20s, were treated for radiation burns at the staging centre at the Snake Valley Golf Club after they had driven from their home to safety.
Rural Ambulance spokesman John Mullen said the pair suffered superficial burns to their face and hands and were taken to Ballarat Base Hospital for observation.
He believes another four people have presented themselves at the hospital for treatment for minor burns.
A Country Fire Authority spokeswoman confirmed two homes had been hit by fire in the Chepstowe area with the grassfire casting spot fires about one kilometre ahead.
An emergency warning was issued on Tuesday afternoon for the Chepstowe district, as the fire burnt through the area around the Beaufort-Carngham and Station Lane intersection.
A blaze at Kentbruck, which flared up last Friday, has burnt though 9000 hectares, but a westerly wind has forced the fire back on itself.
Fire Services Commissioner Craig Lapsley said the fire was not expected to directly hit Dartmoor near the South Australian border, but the town was on the highest alert.
"We don't believe this fire will be controlled today. This will reach into tomorrow due to the conditions in southwestern Victoria," Mr Lapsley told reporters.
Northeastern Victoria was also on high alert with wind speeds getting up to 60km/h and temperatures reaching the low 40s.
"It is serious fire weather in northern Victoria, it is very serious fire weather in southern NSW," Mr Lapsley said.
"Fires that do start will run hard, fast and be very difficult to control," he said.
Victorian fire crews would be positioned at Wodonga and Wangaratta to help respond to fires in southern NSW if required as well as blazes in northeastern Victoria, including Corryong. The Elvis water bomber had also been moved from Essendon to Wangaratta, he said.
Victorian fire crews were also expected to help fight the growing blaze between Cooma and Bega in NSW.
The 64 Victorian firefighters who went to Tasmania on Sunday will return on Thursday and be replaced with a fresh contingent on Friday.
Mr Lapsley said a separate small fire at Sunbury on the Calder Highway had been controlled by 30 fire crews.
An emergency alert was sent to 1400 people in the area, in Melbourne's northwest, via mobile phones and landlines.


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The Coca-Cola Company: 360 Degree Engagement is Important
October 4, 2013
Joseph V. Tripodi, executive vice president and chief marketing and commercial officer of The Coca-Cola Company, discussed how cultural leadership isn't just about the power of advertising, it's Coca Cola's ability to engage in real issues that affect the world.
View highlight video below.
You must be logged in to submit a comment.


text:
Heather Nyberg-Schlotzhauer
Beacon Correspondent
The Eel River Little League is holding their annual election of board members meeting on Monday, Nov. 19 at 7 p.m. at the Rohner Park Recreation Hall in Fortuna.
The ERLL is looking to elect their 2013 board members who will guide them through the season. There are several board positions coming open for the 2013 season and ERLL encourages all interested to apply by contacting Keith Demello at 725-9184 so you can be placed on the ballot.
The meeting is open to the public and all are welcome. ERLL explains, "Current managers, coaches, umpires, board members or any other league volunteer with 20 or more hours of service within the past year are eligible to vote at this General Membership Meeting."
It will not be long before sign ups so keep an eye out for flyers, articles, and updates on the web pages. For more information about the ERLL, email firstname.lastname@example.com or visit www.erllonline.com.


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Topic: Update on my husband
I haven't posted for a while as my husband hasn't been feeling very well and I've been very concerned about him. Two months ago his scan showed ascites in his abdomen, he became jaundiced, and he had a high fever. The doctor decided to change his chemo from Folfiri to gemcitabine. I was not comfortable with this decision but my husband decided to go along with the doctor's recommentation. The doctor also prescribed antibiotics as he thought some of the problems might be caused by infection as well as diuretics to address the ascites.
It appears that the doctor's suspicion of an infection was correct as the ascites and fever have disappeared and bilirubin, albumin and other liver function tests have returned to normal. However, we learned yesterday that the most recent scan shows a bit of tumor progression. The doctor changed the chemo to oxaliplatin and Xeloda and this makes sense to me. We also discussed some other steps that can be taken if this regimen is not successful.
Although the news about the scan was not good, I feel that we are back on the right track. Terry is feeling better and we are determined to stay optimistic and enjoy the rest of the summer.


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I don't remember hearing that Bill Benner is now working for PS&E as Senior Vice President of Corporate, Community and Public Relations and that he has a new blog on Pacers.com. For those that didn't live in Indiana during the 80's and 90's might not be familiar with him but he's been around Indy as a sportswriter, radio talk show host, and at one time worked for the Pacers Media Relations department. He's also remembered as the dude that Reggie would always get in the face of and berate before every Pacers home game as way to psych himself up. Ah... good times. Good times.
Well he has a new blog now and wrote his first post last week after the Pacers big win against the Knicks.
Good Time to Come On Board
Posted by: Bill Benner Posted date: November 22, 2013
Typical or atypical? Ordinary or extraordinary?
As the new kid on this block, I will learn in time.
But Im leaning toward typical and ordinary which, in a word, is amazing.
For certain, I am amazed at what I have witnessed and learned from the time it was announced I was joining Pacers Sports & Entertainment through my first few days on the job.
There was Paul George donating a car to the Hawthorne Community Center as part of his 2013 NBA Most Improved Player Award.
There was a $50,000 Pacers Foundation donation to the World Food Programme to aid recovery from the devastating typhoon in the Philippines.
There were visits by Pacers players to veterans at the Roudebush V.A. Medical Center, which followed the Veterans Day salute to World War II vets who were entertained during a game and then honored in an emotional halftime ceremony.
There was the welcoming and feeding of 650 people for the Come To Our House Thanksgiving dinner, hosted by David and Lesley West and presented by US Foods.
There was Pacers guard George Hill being recognized with the NBAs Community Assist Award on a Friday, then, on a Monday, partnering with the United Way and long-time Pacers season ticket-holder Al Hubbard to award a $25,000 check to an IPS teacher. Even better, Hill was re-united with the Broad Ripple High School teacher who had a profound impact on his life and given the Rockets letter jacket he couldnt afford to buy when he was a prep athlete. The Indianapolis Star gave the heartwarming story Page 1 play.
There was the IPS robotics competition taking place over the weekend, and the proper diligence and care exercised by facilities staff when strong storms blew through the downtown area.
I watched in jaw-dropping amazement at what the PS&E family has come to know as routine the move-in and move-out of two concerts. How that occurs so seamlessly in such a short time is pure wonderment.
And, oh yes, the team. ESPNs Stephen A. Smith stopped by, wanting to do a profile on emerging superstar Paul George. Instead, George insisted it be not just about him, so he was joined by coach Frank Vogel and the other four starters for what became a two-part profile on ESPN.
The Pacers also, as of this writing, ran their record to 10-1, capped by a pulsating overtime win at New York in which George dropped a Reggie Miller-like 28 of his 35 points in the second half and overtime.
And, by the way, both local and national (ESPN) TV ratings for that game blew through the roof while traffic on Pacers.com is so heavy it looks like I-70, I-69 and I-65 in the mornings.
The Pacers even got a two-page spread in the newspaper. A PARIS FRANCE newspaper.
Great team. Good guys. Attendance and ratings and buzz all up, up, up. Community outreach and world notice. The hits just keep on coming. Typical or atypical? Ordinary or extraordinary? Not sure.
But good times all the way around nonetheless. Glad to be on board.


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Monday, August 3. 2009
Blog Administration
Find us on Facebook
Working on the Orange and Brownabout
Sun, 09-24-2017 19:47
Great to see this car being restored. Living in Fla, it's difficult to visit as often as I'd like to. Looking forward to seeing it in IC colors on my [...]
Painting the Yellow Stripe on the 3345about
Tue, 09-19-2017 20:54
I am a fan of heavyweight like John McLoughlin and Mt Harvard. They only need one color Pullman green! Ted Miles
Painting the Yellow Stripe on the 3345about
Sun, 09-17-2017 22:16
Another great job! this looks gorgeous!
Painting the Orange on IC 3345about
Fri, 09-15-2017 21:03
I saw the IC car today and the paint looks wonderful. The car will stand out in a train once it it ready for service. Great job!
The Painted Ladyabout
Fri, 09-15-2017 13:33
Hi there I just wanted to say I really enjoyed working on this car although you forgot to mention my help on working on it.
Working on the Orange and Brownabout
Wed, 09-13-2017 19:32
My understanding is that when IC painted equipment in the orange and brown that yellow went on firsat as the primer coat followed by orange and brown. [...]
Painting the Orange on IC 3345about
Wed, 09-13-2017 17:01
Look great, but you might want to seriously consider getting a pressurized paint pot. These hold 1 to 5 gallons of paint depending on size. This would [...]
The dream, Believe It!about
Sun, 09-10-2017 09:11
From the satellite view on Google maps, that appears to be mostly wooden trestle with one section of iron truss bridge... which by itself is probably [...]
Working on the Orange and Brownabout
Sat, 09-09-2017 20:53
Does that mean that Barn 10 is the designated "Coach Yard"?
The dream, Believe It!about
Thu, 09-07-2017 20:27
That might be a bit too much bridge. Measuring it on Google Maps makes it out to be around 102 feet. Using the same tools, the UP bridge at the river [...]
Working on the Orange and Brownabout
Tue, 09-05-2017 10:17
Hi Matt We estimate the costs for installing 100 amp 240 volt stand by service would be between $2500 to $3000. Our shop is now designated area of [...]
Working on the Orange and Brownabout
Mon, 09-04-2017 09:34
@ Roger, how much would it cost to get this 10oamp 240 service? Because I think that would be a worth-while investment if the museum installed it.


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Organization Development Solutions
Specific types of consulting include:
Team Building -- Custom-designed solutions to meet your team's specific needs (i.e. building trust, improving communication, cohesiveness, leveraging diversity, etc.)
Performance Consulting -- Identification of the primary business goals of the unit and development of the learning solutions needed to enable the realization of those goals
Managing Change -- Strategies for successfully managing change in your organization
Strategic Planning -- Development of a vision and mission, goals, and an action plan (in alignment with the overall university plan) to achieve the desired future
Principled Problem Solving -- Meeting facilitation to analyze, define and solve specific issues
Employee Professional Development -- Facilitation of workshops on a variety of topics such as: behavioral styles, conflict resolution/negotiation; delegation; effective meetings; giving & receiving feedback; influencing others; motivating others; networking; time-management
Other organizational development issues as needed
HR Quick Links
Mailing Address
502 E. Boone Ave.
Spokane, WA 99258-0080
Phone: 509.313.5996
Fax: 509.313.5815
Located at: 102 E. Boone Ave.
Office hours: 8am-5pm, M-F


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Fredericksburg Virginia Family History Center
|This article describes the services and resources available at a Family History Center, a branch facility of the Family History Library.
Center Contacts and Hours
Location & Map:
Address: 20 Boscobel Road, Fredericksburg, Virginia (in southern Stafford County)
- This is not a mailing address. Due to limited staff, Family History Centers
are unable to respond to mail inquiries. Feel free to call during the hours we are open if you have any questions, however.
- The entrance to the Family History Center is at the back of the building across from the satellite dish. Please ring the doorbell.
- Location on Map
Phone: 540 361-7494 or 540 361-4503 (Call during Family History Center hours)
- Tue: 10 am - 8:30 pm
- Wed: 10 am - 8:30 pm
- Thu: 10 am - 2 pm
- Fri: 10 am - 3 pm
- Sat 10 am - 3 pm
Holiday Schedule:
- Closed on all Federal holidays
- Closed the week of Thanksgiving
- Closed December 24, 2012, reopening January 2, 2013
- Center may be closed when Spotsylvania or Stafford County schools are closed due to inclement weather. Please call to determine this.
Center Resources
- FamilySearch Catalog: Microfilm and microfiche may be ordered through the FamilySearch Catalog to be sent to this center.
- The Fredericksburg Virginia Family History Center has a collection of microfilm and microfiche on indefinite loan from the Family History Library in Salt Lake City.
- The Fredericksburg Virginia Family History Center owns about 200 books. The list can be viewed at LibraryThing.com.
Databases and Software
- FHC Portal: This center has access to the Family History Center Portal page which gives free access in the center to premium family history software and websites that generally charge for subscriptions. See this list for details.
Hardware and Equipment
- Six computers for patron use
- One microfilm / microfiche scanner / copier
- One flatbed scanner
- Four microfilm readers
- One microfiche reader
Resources in the Local Area
- Fredericksburg Historic Court Records - "consists of extracts, transcripts and indices of records in repository in the Fredericksburg Circuit Court, Fredericksburg, VA. The information presented by Historic Court Records are primarily extracts of 'loole papers' - the paper trail behind Court Order Book entries... In addition to 'loose paper' records, Historic Court Records also contains a searchable database of early Fredericksburg Land Tax Records." Additional records include Apprenctice Records, Clerk's Order Books, Inquests, Marriage Records and others.
Localities: Fredericksburg, Spotsylvania County, Stafford County, Westmoreland County, King George County, Caroline County
- Central Rappahannock Heritage Center - "The Central Rappahannock Heritage Center, Inc. is a non-governmental regional archives dedicated to preserving for research and posterity materials documenting the lives and work of the people."
Fredericksburg area resources online:
rootsweb.com/~vacfrede/fbgdb.htm - Census, Land & Tax Records, Marriage Records, Government & Miscellaneous Lists, Searchable Newspapers Indexes
rootsweb.com/~vacfrede/index2.htm - Miscellaneous information and links relating to Fredericksburg
FamilySearch Wiki pages
- Fredericksburg (Independent City)
- Spotsylvania County
- Spotsylvania County Genealogy
- Stafford County
- Stafford County Genealogy
- Westmoreland County
- Westmoreland County, Virginia Reserves (Confederate)
- Caroline County
- Caroline County Genealogy
- Caroline County Cemeteries
- Culpepper County
- Culpepper County Genealogy
- Virginia County Resources
- Virginia Court Records
Adding details to a FHC page article.


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Amy Jacobwitz of the Fort Wayne Housing Authority said Ceruti's prepared and delivered the food, free of charge. Jacobwitz said it's wonderful to be able to provide the 108 families living at Brookmill with a meal they couldn't afford to prepare for themselves.
"Every year it just gets bigger and bigger; we are very excited about that." Jacobwitz said.
"This has been a great collaboration," said Joe Jordan, executive director of the Boys and Girls Club.
Jordan said he came up with the idea four years ago, and then got the Fort Wayne Housing Authority, Jane Avery at the Community Harvest Food Bank of Northeast Indiana, Ceruti's, Greater Mount Ararat Baptist Church, as well as Aunt Millie's bakery, on board with the idea.
The long rows of tables were decorated with fall leaves, gourds and fruit, and the placemats were made last year as a project at the Boys and Girls Club. They were laminated drawings depicting what the children were thankful for having.
One had a crayon picture of a large tree on it. Scrawled in crayon block letters it read, "I'm thankful for trees." Another read "I am thankful because I love my family."
Judging by the happy faces on the adults and children they were all thankful for the good food and camaraderie the evening provided.


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Performance Management Program for Staff-CANCELED
- When:
- Location:
- Student Center
- Room:
- 301
- Description:
Training has been developed that supports an enhanced understanding of how UB's improved performance management program works, the role of supervisors and the engagement of staff. This 90-minute training is designed for non-supervisory staff.
- Contact Name:
- Mark Emmel
- Contact Email:
- email@example.com
- Contact Phone:
- 410.837.4399
If you need accommodations to participate in this event, please contact the person listed above at least 10 days prior to the event.


text:
Is Facebook Shutting Down?
The rumors are everywhere. Facebook shutting down on March 15th? Say it isn't so! Well, according to the people at Facebook, it isn't. But, where did these rumors come from?
Most experts' best guess is that it came from an article by the satirical Weekly World News a few days ago. It's caused a frenzy of posts from people and the beginning of a group to stop the shut down from happening.


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Student rep info: name, email, ph #
Offered in partnership with
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Want to increase your effectiveness as a science teacher for the middle grades? Join us and learn about the nature and history of science as well as how to help students in this age group grasp the scientific method.
You'll receive lots of worksheets and specific examples of some great experiments you can use in your own classroom. We'll cover principles of direct instruction and many different learning and organizational tools that will benefit your students. You'll even learn how you can use science class to improve the emotional climate in your classroom!
All through the course, we'll provide worksheets and check lists you and your students can put to immediate use. You'll see how helpful they are in the lessons on the scientific method, writing a research paper, and producing a science fair. We'll also cover foundational content in both physical science and life science. You'll learn how to use a study of the earth's atmosphere to teach students how to make and interpret a variety of graphs—an important skill for standardized testing.
By the end of the course, you'll have gained knowledge about both science and teaching methods. Your confidence will soar and you'll have many new skills that will benefit both you and the children you teach. You'll also learn about some of the best Web sites available to science teachers—they'll be great resources for you! And we'll all benefit from the Discussion Area where you can share your experiences and profit from the experiences of your fellow teachers.
Note: To receive 25 hours of instruction in the State of Oregon, please ensure your school is eligible to issue professional development units, and that the course is approved by your professional learning coordinator.
A new session of each course opens each month, allowing you to enroll whenever your busy schedule permits!
How does it work? Once a session starts, two lessons will be released each week, for the six-week duration of your course. You will have access to all previously released lessons until the course ends.
Keep in mind that the interactive discussion area for each lesson automatically closes 2 weeks after each lesson is released, so you're encouraged to complete each lesson within two weeks of its release.
The Final Exam will be released on the same day as the last lesson. Once the Final Exam has been released, you will have 2 weeks plus 10 days to complete the Final and finish any remaining lessons in your course. No further extensions can be provided beyond these 10 days.
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Holly Trimble earned a bachelor's degree in physical therapy from the University of Colorado, a master's degree in pediatric physical therapy from Boston University, and a master's degree in biology from the University of Nebraska at Kearney. She also completed an additional 15 credit hours in education at the doctoral level. After working as a physical therapist for many years, Holly transitioned into teaching. She taught math and science to sixth-graders for several years at a private school, and also worked as a private tutor for children with learning disabilities. She has lectured on health-related topics to all age groups, from school-age children to adults, and she now works as an adjunct professor, teaching college-level anatomy and physiology. She received an Adjunct Faculty Excellence Award from her college and is the author of the eBook, College Success Now! as well as several ed2go courses.
I really enjoyed the content of the course and the way it was presented. I gained a lot of scientific knowledge that I perhaps had forgotten. I also gained valuable techniques in conducting not only a science class, but will be able to integrate them into my other contents. Thank you.
I really enjoyed this class! The instructor's teaching style was very clear, direct, and methodical. She covered all of the topics thoroughly, and wrote in a very friendly and interesting style. As I finished each lesson, I was already looking forward to the next! Also, the supplementary materials and resources at the end of each lesson are so valuable and will be very useful to me. I am sure I will refer to all the materials in this course over and over again.
I got a lot more from than course than I expected. I am not a science teacher by training, and taking this class gave me a lot of foundational information that I did not have. Also, as a special education teacher, I really appreciated this instructor's heart for students with disabilities. She presented very useful information for the general education teacher and provided different approaches so special education students could also be given the opportunity to learn. The resources for science fairs are gold to me.
The instructor, Holly Trimble, is very good at getting to the core of instruction. In the past, I had felt like I was teaching bits and pieces of scientific information. It was not until I read the chapter on the drive for equilibrium that I saw it all tied together. But, I had never been able to put that into words to let my students understand that concept. I teach high school science and math, and I found this course invaluable. I will use what I learned in these lessons every day in class!
This was the best education course I have ever taken. The lessons were great and the resources given at the end of each lesson were terrific. I wish I had taken this course many years ago - my students would have benefited from it!
This was a very helpful course and the instructor was wonderful! She broke down the information into manageable chunks and included real classroom stories. She also included a ton of supplementary information to help us research anything we might need to use in our classrooms. I made a notebook of all the lessons, and I know it will be a very useful guide for me this year!
I have taken many science courses in my teaching career, but no course has really taught me science and how to use it in my classroom like this one! It has been previously hard for me to teach science because I never understood it myself. Science concepts were never explained in a way that I could understand them until now. I will never again dread teaching science. Thank you so much!
This was a great course to not only refresh one's science knowledge, but also to gain a ton of great science teaching ideas, both in terms of content and execution. The instructor provides lots of great checklists and worksheets for both the students and teacher. I highly recommend this course. If you still rely on just worksheets and the "occasional" activity or experiment this course will change how you approach teaching science and make science the most exciting part of the day for your students.
The instructor did an outstanding job of presenting a comprehensive, insightful science class for teachers of fourth to sixth graders. She truly led by example. The class has been such a boost for me, and I'm sure for the others who've taken it. I am more knowledgeable and have more tools to start using with my students tomorrow! Her willingness to share such complete resource lists and expertise tell of her love for students and teachers alike. Thank you!
I was so pleased with this class. So much was covered that helped me to become a better teacher: science concepts, lesson planning, organizing units, classroom management. and more. I appreciated the knowledgeable, common-sense approach of the teacher and am excited to share this love of science with my students in a more coherent way this fall. Thank you!!
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"… a well-balanced vegetarian diet can provide for the needs of a growing child and adolescent …" Lacto-ovo-vegetarians eat no animal products, except dairy products and eggs. Vegans eat no animal products. Macrobiotic diets may include animal products, but are made up of grains, legumes, and vegetables. Plant foods can include all essential amino acids […]View Post
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ASHBURN, Va. (AP) — Tight end Chris Cooley has passed a physical exam and agreed to rejoin the Washington Redskins.
Cooley's return to the Redskins on Monday comes a day after tight end Fred Davis was lost for the season with an Achilles tendon injury during Washington's 27-23 loss at the New York Giants.
Cooley was released in August by the Redskins, the team he spent his entire eight-season NFL career with. He is a two-time Pro Bowl pick and his 428 catches are the franchise record for a tight end.
Injuries limited Cooley to five games and eight receptions last season.
Source: Associated Press


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Editor's note: This report contains graphic content that some readers may find disturbing.
CRESCENT CITY -- Former mixed-martial artist Jarrod Wyatt was sentenced today for brutally mutilating and murdering his friend after drinking psychedelic mushroom tea.
Wyatt, 27, pleaded guilty last month to first degree murder involving mayhem, with a special enhancement for using a weapon. He received 47 years to life in prison.
Wyatt had previously entered dual pleas of not guilty and not guilty by reason of insanity, leading to multiple psychiatric examinations. A Del Norte County judge ruled in May 2012 that Wyatt was competent to stand trial.
Wyatt murdered his friend Taylor Powell, 21, in the early morning hours of March 21, 2010, after the two men and two other acquaintances reportedly took psychedelic mushroom tea. Wyatt later attacked Powell, brutally killing him by ripping his heart out while he was still alive.
According to court documents, Wyatt was arrested after Del Norte County Sheriff's Department deputies and Yurok Tribal Police arrived at a Requa home near the mouth of the Klamath River, finding him naked and covered in blood from head to toe. When officers approached Wyatt, the documents state he told the officers, "I killed him," and said he had cut out Powell's heart and tongue.
Officers searched the residence and found Powell dead on the couch, his chest cut open, his heart, tongue and the skin of his face removed, court documents said. An autopsy determined that the organs had been removed while Powell was still alive. What was later determined to be Powell's heart was found charred in a wood-burning stove in the residence, according to Dr. Neil Kushner, who performed the autopsy.
At the time of the plea deal, defense attorney James Fallman said Wyatt decided at the last minute that he didn't want to take the stand, and didn't want his family members to testify. He said a plea deal was the only way to give Wyatt the opportunity to go before a parole board at some point in the future.


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Success is due less to ability than to zeal. --Charles Buxton
The only thing you need to know about this market since the first of the year is that buyers still want in. News, fundamentals, technicals and pretty much everything else has been irrelevant. The buyers have been in the driver's seat and they just keep on pressing.
In this sort of market my advice to stay with the trend and avoid calling market tops has worked well, but it isn't as easy as it sounds. There has been quite a bit of choppy action lately and it is easy to find yourself in the wrong individual stocks if you aren't careful. Plenty of stocks are hitting new highs but the leadership is narrow and strength has been muted lately.
Yesterday I was particularly disappointed with the number of intraday reversals on my screens. The early spikes invited more profit-taking than chasing and that was quite costly if you didn't do a little selling at the right time.
The dilemma is that there is still nothing really wrong with the market action. There is no major change in market character, although there are some niggling negatives. It would be very easy to be more anticipatory about a market turn, however, that has not been a smart thing to do for a long time.
My biggest problem is that I prefer the market pull back and shake things up a bit, rather than continue this slow drift upward. I'm finding it increasingly difficult to keep money at work and that is going to be the case until there's some sort of shakeup.
Yesterday's intraday spike to highs felt very computer driven, and I suspect the computers are all programmed to focus on squeeze-type action since there are so many people looking for at least a minor pullback. Even the bulls would like to see a little downside now and then to allow for better entries.
The easiest thing in the world to do is to keep trying to predict a top. It is very tempting, but until there is hard proof of some sort of change in the market character, it is just wishful thinking.
Keep looking for setups and keep plugging away. Let the attention-seeking pundits make the big dramatic calls while we focus on making money while we can.
The president's State of the Union address doesn't seem to have had much market impact and there's a slightly positive start, with some help from strength in Europe. There are no major economic reports today, but there are still quite a few earnings report, with Cisco (CSCO) of interest tonight.


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Model Type
27 Combined MPG (25 city / 30 hwy)
EPA estimated
A full list of available features and filters for the used 2017 Mitsubishi Outlander inventory include but are not limited to: Edmunds Special Offers: Purchase Offers, Lease Offers, Gas Card (4), Used Offers (4). Model Type: SUV (13).
Trims: SE (3), ES (4), SEL (1), GT (5), LS, XLS, Limited. Features: Fold Flat Rear Seats (13), Rear Bench Seats (13), Audio and cruise controls on steering wheel (13), Alarm (13), Stability Control (13), Trip Computer (13), Tire Pressure Warning (13), Third-row seating (13), USB Inputs (13), Bluetooth (13), Auto Climate Control (13), Back-up camera (13), Multi-Zone Climate Control (13), Heated seats (9), AWD/4WD (10), Keyless Entry/Start (9), Aux Audio Inputs (9), Apple Carplay/Android Auto (9), Power Liftgate/Trunk (5), Leather Seats (6), Power Driver Seat (6), Sunroof/Moonroof (5), Electronic Folding Mirrors (6), 3500lb Towing Capacity (5), Upgraded Stereo, Upgraded Headlights (5), Parking sensors (2), Navigation, Towing Hitch, Remote Start (2), Adaptive Cruise Control, Blind Spot Monitoring (5), Lane Departure Warning, Pre-collision safety system, Rear Entertainment System. Engine/Mechanics: 4 cylinders (8), 6 cylinders (5). Transmission: Automatic (8). Fuel Type: regular unleaded (8), premium unleaded (recommended) (5), premium unleaded (required). Drivetrain: all wheel drive (10), front wheel drive (3).
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Mildly updated after a more thorough redesign last year, the 2017 Mitsubishi Outlander continues as a moderately priced choice for consumers looking for a small SUV with three rows of seats. And even though that third row is really only suitable for small children, the extra capacity could be a deciding factor for large families shopping on a budget. In addition, the Outlander also is available with a V6 engine, something many of its competitors lack. But even with those advantages, in some areas the Mitsubishi lags behind its competitors in the red-hot compact SUV market.
The 2016 refresh included revamped exterior styling, an upgraded interior, some chassis tweaks and updated electronics. Changes for this year include a standard 6.1-inch touchscreen for the infotainment system and a standard rearview camera. Optional equipment now includes auto high-beam headlights, a suite of advanced safety technology, a 360-degree camera, and Apple CarPlay and Android Auto functionality. In addition, all-wheel drive is now available on the base ES model.
The interior is definitely the Outlander's strongest selling point. In addition to seven-passenger seating, buyers will like the quality materials, clean design, available driver-assist features and decent cargo capacity. One sticking point may be the infotainment system's user interface, which is not as easy to use as that of most of the Outlander's competitors.
The standard powerplant for the ES, SE and SEL trim levels is a 2.4-liter four-cylinder engine that produces 166 horsepower and 162 pound-feet of torque and comes linked to a continuously variable automatic transmission (CVT). The GT model comes with a standard 3.0-liter V6 that puts out 224 hp and 215 lb-ft of torque and comes mated to a six-speed automatic transmission. The GT is equipped with standard all-wheel drive, a feature that is optional on the first three trim levels.
On the road, the Outlander handles well enough for a vehicle in its class, but most drivers will probably find engine performance to be subpar compared to the competition. Neither engine is particularly lively, and the four-cylinder version is both underpowered and noisy. As a vehicle for city commuting, the Outlander could work fine, but there are likely better choices for highway travel or serious off-road use.
Fuel economy is another area where the Outlander is a little below average for its class. The base two-wheel-drive model with the four-cylinder engine is EPA-rated at 27 mpg combined (25 city/30 highway). The GT trim, with all-wheel drive and the V6 engine, is rated at 23 mpg combined (20 city/27 highway).
The base ES model comes fairly well equipped with such features as heated side mirrors, alloy wheels and dual-zone automatic climate control. But only the higher trims offer such features as� adaptive cruise control, blind-spot monitoring, Apple CarPlay and Android Auto, and a premium sound system. And only the top-of-the-line GT gets the V6 engine. Whatever your needs, let Edmunds help you find the right 2017 Mitsubishi Outlander for you.
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Conceived in 1984 as a surfboard manufacturing company, it wasn't until 1992 that Insight launched its clothing line to complement its already-established board brand. Hailing from the land down under (Sydney, Australia) Insight's surf heritage is evident in its designs and garments. Founder, creative director, and ex-pro surfer Drew Down was passionate and adamant about creating a fashion-led lifestyle label that encompasses surf, skate, art, music, fashion, and popular culture. Insight's unique style has been termed "garage art," which takes pop culture and infuses it with street art motifs. Drawing inspiration from iconic artists like Jean Michel Basquiat and Andy Warhol, Insight is leaving their mark on the fashion world and is distributed to over 40 countries all over the globe.
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Bright Side Alarm Clock
No longer available
- Overview
Wake up on the bright side every morning. This retro-styled digital clock has what you need to get going.
- 4" wide x 2.5" deep x 2.5" high
- Clock has an alarm and a snooze button.
- The multicolored backlight makes the big numbers pop.
- Requires two AA batteries (not included).
- Dimensions + Care
- Overall: 4" wide x 2.5" deep x 2.5" high
- Display: 3" wide x 1.3" high
- Dust with a soft, dry cloth.
- Shipping Info
This item will arrive in 3-5 business days. Please proceed to the Payment & Review page of Checkout for a precise delivery estimate.
- Final Sale
Final-sale items, identified by a price ending in $0.99, cannot be returned. Once placed, your order for any final sale items cannot be canceled.


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Spinach with Pan Roasted Red Peppers and Goat Cheese
I love finding new recipes to use as a side dish or to use a vegetable in a new way. Spinach is a veggie that I'm kind of picky about. I love it raw in salads and on sandwiches, but I'm not a big fan of cooked spinach being the star of a side dish. This recipe has changed that opinion for me. Hubby and I thoroughly enjoyed this spinach recipe and it's a snap to throw together.
I upped the garlic in the recipe since we love our garlic. I wasn't sure how much "two bunches" of spinach came out to, so I just used a 7 oz bag of baby spinach. It looks like our dish was a little light on the spinach to pepper ratio, but we both really liked it, so I'll be making it this way in the future.
Spinach with Pan Roasted Red Peppers and Goat Cheese
Yield: 2
1 Tbsp olive oil
1 red pepper, sliced into thin strips
3 cloves garlic, minced
7 oz baby spinach
2 tsp lemon juice
salt and pepper
2 oz crumbled goat cheese
Heat the olive oil in a pan over medium-high heat and add the peppers.
Cook a couple minutes, until the skins are slightly darkened, and then turn down the heat to medium, continuing to cook for an additional 3 minutes or until tender.
Stir in the garlic and sauté until fragrant.
Add the spinach and cook, stirring occasionally, until wilted.
Stir in the lemon juice and salt and pepper to taste.
Just prior to serving, sprinkle with goat cheese.
Recipe adapted from Elly Says Opa
6 Responses to "Spinach with Pan Roasted Red Peppers and Goat Cheese"
Looks delicious! Glad you liked it, and love the goat cheese swap. 🙂
This looks great! I love spinach and this is a nice twist!
what a bright tasty looking dish!
love those pictures, so bright! and definitely a delicious dish, so much of my favorite things 🙂
Mmm spinach and goat cheese. One of the best combos… EVER. haha 🙂
My honey and I can't get enough spinach, and while we've made something similar to what you made, we've never tried it with the pan roasted peppers. That sounds like the perfect addition!!! I just know I'd love it! 🙂


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The Boston Red Sox's bullpen was considered among the majors' best earlier this season but has been decimated by injuries. The team now is down to Plan C at closer.
With Andrew Bailey (biceps) and Joel Hanrahan (forearm) on the disabled list, manager John Farrell plans to use the relatively unknown Junichi Tazawa in save situations.
"I think what we'd love to do is close Tazawa. We'd keep Koji (Uehara) in that eighth inning role that he's been in," Farrell told The Boston Globe. "Fortunately we do have some depth to turn to internally and we know that we've got to get through these next couple of days to kinda regroup. ... So we're kind of breathing a little thin ice down there right now and just trying to manage the best we can to get through these next couple of days to regroup."
Tazawa is 2-1 with a 2.51 ERA and 18 strikeouts in 14 1/3 innings this season and quietly had a strong 2012 season (1.43 ERA, 9.2 K/9 in 37 appearances). However, he has only one career save in parts of four major league seasons.


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Posted 5 years ago
(4 items)
The Boston Type Writer,
Patented May 18, 1886
The Boston typewriter was patented by Daniel E. Kempster in 1886 and was marketed for a brief period in 1888. Its most prominent features include a large curved index for character selection and the name "BOSTON" cast into a pediment reminiscent of classical Greek architecture. Operating a Boston involved placing a sheet of paper on a flat bed, which moved left to right across the center portion of the typewriter, and selecting a character to be printed with the index arm . The index arm would in turn rotate a large character wheel in the center of the typewriter to the corresponding letter on the index. Depressing it caused the desired character to push downward and be printed, the paper carrier would then move one space allowing for the next character to be printed. Inking was accomplished with a ribbon. Sound complicated? It certainly was. For an index typewriter, which was typically designed to be simple and inexpensive, the Boston was quite a complex writing machine. The Boston was short lived and very few have survived.
The images displayed here are of the Boston typewriter, Serial #54, from my personal collection & can also be viewed at: www.typewritercollector.com


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Welcome to the database of the Council of Europe.
The database is endowed with a search engine which, through a pre-defined search, a simple search with a password or an advanced search with different criteria, will allow you to access all of the documents, publications and reports made available to the public by the Pompidou Group.
We are endeavouring to integrate this database of documents produced over the last ten years, with the exception of ISBN publications (available from the Council of Europe online Bookshop or from the Pompidou Group).
If by following the above process it is still not possible to locate the document that you are searching for, we would be grateful if you could contact us by email
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To access the pre-defined search tool by activity sector, you will find below, for each of the
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To extend your search by sector or by theme, other default searches are offered:
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|Date / Time
|Thursday March 17, 2016 @11:14PM
|Anonymous Doxes Trump, But Leaked Info Underwhelms
|Monday March 07, 2016 @12:21PM
|Anonymous Claims Twitter Is Suspending 'OpISIS' Member Accounts
|Saturday March 05, 2016 @05:18PM
|Anonymous Hacks Donald Trump's Voicemail and Leaks the Messages
|Monday February 29, 2016 @12:17PM
|Anonymous Goes After Miami Police Officer Who Doxed An Innocent Woman
|Thursday February 18, 2016 @10:04PM
|Anonymous Hacker Gets Lost At Sea, Rescued, Then Arrested
|Friday January 29, 2016 @04:43PM
|The Dark Arts: Meet the LulzSec Hackers
|Tuesday December 15, 2015 @09:39AM
|European Space Agency Records Leaked For Amusement, Attackers Say
|Saturday December 12, 2015 @10:26AM
|Anonymous Goes After Donald Trump
|Tuesday November 03, 2015 @12:05PM
|Anonymous Says US Senators Were 'Incorrectly Outed' As KKK Members
|Tuesday May 12, 2015 @12:23PM
|Anonymous Accused of Running a Botnet Using Thousands of Hacked Home Routers
|Sunday May 03, 2015 @10:06PM
|VA Tech Student Arrested For Posting Perceived Threat Via Yik Yak
|Monday April 27, 2015 @11:02AM
|Indian Telecom Authority Releases a Million Email IDs, Taken Down By Hackers
|Thursday February 12, 2015 @11:49AM
|US Gas Pump Hacked With 'Anonymous' Tagline
|Sunday January 25, 2015 @05:23PM
|Anonymous Asks Activists To Fight Pedophiles In 'Operation Deatheaters'
|Thursday April 24, 2014 @10:09AM
|Anonymous' Airchat Aim: Communication Without Need For Phone Or Internet
|Saturday March 08, 2014 @10:21PM
|A Dispatch From Outside the Prison Holding Barrett Brown
|Thursday December 05, 2013 @11:14AM
|eBay Founder Pleads For Leniency For the PayPal 14
|Saturday November 16, 2013 @11:28AM
|FBI Reports US Agencies Hacked By Anonymous
|Monday April 22, 2013 @11:12AM
|Is Anonymous Going Mainstream Following Website Funding?
|Sunday April 07, 2013 @09:27AM
|Anonymous' "OpIsrael" Has Little Impact
|Friday February 22, 2013 @08:32AM
|Illinois Politician Wants a Kill Switch For Anonymous Speech Online
|Sunday January 27, 2013 @06:21AM
|Anonymous Warhead Targets US Sentencing Commission
|Thursday January 24, 2013 @04:30PM
|UK Anonymous Hacktivists Get Jail Time
|Tuesday January 15, 2013 @09:56AM
|Linguistics Identifies Anonymous Users
|Wednesday January 09, 2013 @08:30AM
|Anonymous Helps Find Evidence In Gang Rape Case
|Sunday December 16, 2012 @08:30PM
|Anonymous Hacks Westboro Baptist Church
|Friday November 30, 2012 @08:15PM
|Syrian Malware Servers Survive, Then Die
|Saturday November 24, 2012 @08:26AM
|"Anonymous" File-Sharing Darknet Ruled Illegal By German Court
|Friday November 23, 2012 @07:03PM
|Stratfor Hacker Could Be Sentenced to Life, Says Judge
|Sunday November 18, 2012 @08:29PM
|Anonymous Attacks Israeli Websites In Response To IDF Operation In Gaza
|Thursday October 25, 2012 @02:02PM
|Anonymous' WikiLeaks-Like Project Tyler To Launch In December
|Tuesday September 04, 2012 @08:41AM
|Anonymous Leaks 1M Apple Device UDIDs
|Tuesday August 28, 2012 @09:22AM
|Hackers Dump Millions of Records From Banks, Politicians
|Saturday July 07, 2012 @09:34AM
|Anonymous Lists Sites. and VoIP Services, Blocked In the UAE
|Saturday May 19, 2012 @06:25PM
|'First Base' In Greek Courts For ISP-Level Blocking
|Thursday May 17, 2012 @03:11PM
|The Pirate Bay Returns, Anonymous Hater Takes Credit For DDoS
|Thursday May 10, 2012 @08:33AM
|Pirate Bay Criticizes Anonymous' Attack On Virgin
|Sunday April 22, 2012 @12:41PM
|Anonymous, People's Liberation Front Build Anonymous Data-Sharing Site
|Saturday April 07, 2012 @08:12PM
|Anonymous Hacks UK Government Sites Over 'Draconian Surveillance'
|Thursday March 01, 2012 @09:19AM
|25 Alleged Anonymous Hackers Arrested By Interpol
|Tuesday February 14, 2012 @01:19PM
|Did Anonymous Take Down CIA.gov?
|Friday February 10, 2012 @02:29PM
|Hacked Syrian Officials Used '12345' As Email Password
|Tuesday February 07, 2012 @10:09AM
|Cops Set Up Extortion Sting On Symantec's Source Code Thieves
|Saturday January 21, 2012 @07:32AM
|Downloads of DoS Attack Tool LOIC Spike
|Wednesday January 04, 2012 @02:26PM
|Cleaning Up the Mess After a Major Hack Attack
|Wednesday November 02, 2011 @07:31PM
|Anonymous Cancels Drug-Ring Attack
|Saturday October 22, 2011 @09:25AM
|Anonymous Hackers Take Down Child Porn Websites
|Tuesday September 13, 2011 @11:39AM
|Purported FBI Report Calls Anonymous a National Security Threat
|Tuesday August 16, 2011 @11:53AM
|Aaron Barr Talks About DEFCON, Anonymous Attacks
|Saturday August 13, 2011 @11:35PM
|After Cell-Phone Switch-Off, Anonymous Promises BART Protest
|Monday August 08, 2011 @04:20PM
|Building a Better 'Anonymous?'
|Monday August 01, 2011 @06:44PM
|UK Police Charge Suspected Anonymous Spokesman
|Friday July 22, 2011 @07:36AM
|Anonymous Releases Restricted NATO Document
|Thursday July 21, 2011 @10:04AM
|Anonymous Hack One Gigabyte of Data From NATO
|Wednesday July 20, 2011 @10:25AM
|FBI Arrests 12 In 'Anonymous' Hackers Probe
|Monday July 18, 2011 @04:07PM
|Anonymous Creates Its Own Social Network
|Thursday July 14, 2011 @12:52PM
|McCain Asks For Committee On Wikileaks, Anonymous
|Tuesday July 05, 2011 @12:02PM
|Italian Anonymous Hacker Cell Arrested
|Thursday June 30, 2011 @06:06PM
|LulzSec, Anonymous Reason For PROTECT IP Act, Says RIAA
|Thursday June 30, 2011 @05:51PM
|Anonymous Leaks New Batch of Data
|Monday June 20, 2011 @12:31PM
|LulzSec Teams With Anonymous, In Operation AntiSec
|Monday June 13, 2011 @04:53PM
|Turkish Police Nab 32 Suspects Tied To Anonymous
|Friday June 03, 2011 @06:07PM
|Anonymous Steals 10,000 Iranian Government Emails
|Thursday June 02, 2011 @01:58PM
|NATO Report Threatens To 'Persecute' Anonymous
|Friday May 20, 2011 @06:34PM
|German Police Seize German Pirate Party Servers
|Wednesday May 11, 2011 @11:45AM
|Mainstream Media Looks at Anonymous
|Monday May 09, 2011 @08:36AM
|Anonymous Under Civil War?
|Thursday May 05, 2011 @07:04PM
|Anonymous Denies Sony Claims of Disruption, Credit Info Theft
|Thursday May 05, 2011 @11:50AM
|Sony Officially Blames Anonymous For PSN Hack
|Sunday May 01, 2011 @09:25AM
|Playstation To Restore Services This Week
|Thursday April 28, 2011 @01:09PM
|Geohot Denies Involvement In PSN Hack Attack
|Friday April 08, 2011 @06:29PM
|Anonymous Launches Attack On Sony
|Monday March 14, 2011 @12:45PM
|Anonymous Leaks Internal Bank of America Emails
|Sunday March 06, 2011 @11:01PM
|HBGary Hack In Depth
|Tuesday March 01, 2011 @07:27PM
|Contents of Leaked HBGary Emails Reveal Wrongdoing
|Monday February 28, 2011 @05:17PM
|HBGary Federal CEO Aaron Barr Steps Down
|Friday February 18, 2011 @08:28PM
|Anonymous Goes After GodHatesFags.com
|Wednesday February 16, 2011 @10:59AM
|Attacked By Anonymous, HBGary Pulls Out of RSA
|Sunday February 13, 2011 @10:28AM
|Anonymous Claims Possession of Stuxnet Worm
|Friday February 11, 2011 @08:22AM
|Thrifty, Anonymous Benefactor Backs Up BBC Websites Before They Go Dark
|Monday February 07, 2011 @01:19PM
|HBGary Federal Hacked By Anonymous
|Thursday January 27, 2011 @10:13AM
|Police Arrest Five Over Anonymous Attacks
|Friday December 31, 2010 @12:54AM
|FBI Raids Texas ISP For Anonymous DDoS Info
|Thursday December 16, 2010 @09:31AM
|Scotland Yard Has Been After Anonymous For Months
|Monday December 13, 2010 @03:26PM
|4chan Declares War On Snow
|Monday December 13, 2010 @03:16PM
|Amazon Says Hardware, Not Hackers, Caused Outage
|Saturday December 11, 2010 @08:53AM
|Angles On Anonymous
|Friday December 10, 2010 @10:28PM
|'Anonymous' WikiLeaks Proponents Not So Anonymous
|Tuesday October 19, 2010 @10:20AM
|Gene Simmons Threatens Anonymous Again and Gets DDoS'd
|Sunday September 19, 2010 @08:27AM
|DDoS From 4chan Hits MPAA and Anti-Piracy Website
|Wednesday April 14, 2010 @01:46PM
|Canadian Judge Orders Disclosure of Anonymous Posters
|Friday March 05, 2010 @10:50AM
|China's Human Flesh Search Engine
|Monday February 15, 2010 @09:54PM
|Operation Titstorm Hits the Streets
|Friday February 12, 2010 @10:28AM
|Anonymous Speaks About Australian Gov't. Attacks
|Wednesday February 10, 2010 @04:44PM
|Hackers Attack AU Websites To Protest Censorship
|Sunday October 25, 2009 @08:55PM
|When Software Leaks (and What Really Goes Down)
|Wednesday April 15, 2009 @01:17AM
|Slashdot Mentioned In Virginia Terrorism Report
|Tuesday February 12, 2008 @07:26AM
|"Anonymous" Takes Scientology Protest to the Streets
|Thursday February 07, 2008 @03:01PM
|Does Anonymity In Virtual Worlds Breed Terrorism?
|Friday January 25, 2008 @07:37PM
|Internet Group Declares War on Scientology


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Beam Inc. Successfully Expands Vistaar Implementation to Drive Pricing Strategies
Vistaar Technologies, Inc., a provider of price management solutions, announced today that Beam Inc. has completed the third major phase of its Vistaar beverage alcohol pricing solution implementation. With Vistaar, Beam has been able to better manage its multiple-state pricing protocols while enabling visibility across the entire three-tier value chain to improve price management decision making. Beam's pricing system includes 130 users across marketing, sales, and pricing, and helps manage prices for 3,500 unique SKUs across the company's 75 U.S. distributors.
Beam's Vistaar pricing system has been live since September 2009, facilitating improvement in the company's price execution process. During the first two phases of the Vistaar implementation, Beam established a standardized price structure planning platform to drive price execution with its distributors. The third-phase rollout includes the latest business release of the Vistaar pricing solution, providing greater enterprise visibility to activity across price structures and workflows. The latest Vistaar version also enables deal-level evaluation, distributor margin evaluation, brand comparisons, better visibility into national account pricing and improved price structure execution with more informed price changes.
"Vistaar has greatly impacted Beam's ability to develop and deliver effective price strategies," said Brendan Lynch, senior director of North American strategy and revenue management with Beam, which has had a successful first quarter price increase across many brands in its portfolio. "Each successive phase of implementation has increased value chain visibility and improved our ability to manage price, promotions and mix. We anticipate our expanded Vistaar solution will further our insights and identify pricing and growth opportunities."
"We are pleased that Beam continues to successfully leverage the Vistaar beverage alcohol pricing solution to improve its bottom line results and deliver greater value to its customers," said Manoj Menon, vice president of product management with Vistaar. "Vistaar's proven pricing technology leadership and innovation will continue to help Beam meet the challenges associated with pricing its large product portfolio in a complex marketplace."
About Vistaar Technologies, Inc.
Vistaar is a leading provider of price management solutions that enable companies to achieve pricing best practices through price analytics, price optimization, price list management and deal management. Its technology transforms pricing operations into a strategic advantage for some of the world's largest manufacturers, distributors and service providers. For these companies, Vistaar pricing solutions drive measurable price and margin improvements to deliver profitable growth and maximum shareholder value. Vistaar's operations include six offices across North America, Europe and Asia. For more information, visit www.vistaar.com or call at (973) 581-6300.


text:
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I have about 3-4 years of playing under my belt and I learned to strongarm (with pretty good form) will consistent/controlled drives about 330ft on average. I took a few years off and came back to the game (throwing 300 or so with brute force). I spent a week reading all of the great info put out on these forums in the last few years and decided to retool my drive. I spent a week throwing from a standstill (pec drill) and got my standstill drives up to 290' to 300ft'. I added a rough runup and measured my drives and I started throwing 330' to 340'.
I suspect I didn't have snap for 2 reasons. 1) I injured my index and middle fingers during what I might call "grip lock" during my pec drills. 2) My rip point was wonky. I couldn't get even pressure between my thumb (or thumbpad) and index finger. I never felt the pivot and the disc seemed to slip out.
I went back out and bent my thumb (close to 90 degrees) so I would be pinching the disc between it and my index finger to see what happened. It wasn't super comfortable, but I may be able to get accustomed to it. But I could begin to feel the disc pivot (not cleanly or smoothly, but I felt it) when I threw and I started throwing 350' - 375'. I did notice significant "wobble" (not sure if it was OTA or not) so I know I need to work on a smoother release. But I have two questions -
1) Is it anyone's opinion that I keep my thumb bent to improve the "rip point"? or should I keep with my old style of thumb pad over index finger rip point (it feels offcenter though)
2) What is the best way to heal strained tendons/ligaments in my index and middle fingers? and if I learn to throw correctly, will it still hurt (it seems to hurt every 3rd or 4th throw)?
Thanks for all the great discussions about throwing/snapping, etc. I think I'm going to get it eventually.


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The Trinity
Yo, Yo, Yo...
The plan of my blog is simply to discuss who in my opinion, has been misused and forgotten in the WWE, when they simply should not have been.
I won't pick out too many names, but I'd like to analyse some of my personal favourites who didn't quite measure up for whatever reason, and whoevers fault it may be.
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We are gathered here today to celebrate the life of the WWE Divas and mourn our loss…
…This isn't a funeral is it?
Well, not yet, at least…
I appreciate the title for this is somewhat obscure, but beating around the bush is something I'm not a big fan of. Bluntly, the Divas competition in the WWE is dead.
I'd like to point out how the
Hello all, This is my first blog on the website.
For a little bit of Background info on myself, I used to run a Wrestling news website when I was 11 years old, a guy called Peter Staniforth used to submit his interviews to me to host in an effort to promote himself and my website too. A result of this was me getting into contact with Shark Boy, Doug Williams and many more...The beginning


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I'm still surprised no one has brought up Omar Vizquel's name. He has said he wants to play another year. Switch hitter and would be a great mentor to Cozart.
I'm still surprised no one has brought up Omar Vizquel's name. He has said he wants to play another year. Switch hitter and would be a great mentor to Cozart.
Kepp brings nothing that Frazier doesn't trump.
Stubbs absolute kills LHP and his numbers in the 2 hole are as follow:
Drew Stubbs 2011 AB AVG OBP SLG OPS
vs. Left 113 .319 .418 .478 .896
vs. Right 491 .226 .298 .338 .636
Batting #1 408 .250 .329 .373 .702
Batting #2 22 .364 .462 .500 .962
Batting #6 127 .220 .291 .323 .614
Batting #7 31 .161 .235 .290 .525
Batting #8 11 .273 .333 .455 .788
Batting #9 5 .200 .333 .400 .733
2B B.Phillips
CF D.Stubbs/Heisey
1B J.Votto
LF Ludwick
RF J.Bruce
3B S.Rolen/Francisco
C Hanigan/Mesoraco
SS Z.Cozart
Stubbs and Heisey should split the time in Center at worst and IMO Heisey should get the majority of all AB's against rightys.
Chris Heisey 2011 AB AVG OBP SLG OPS
vs. Left 61 .197 .258 .295 .553
vs. Right 218 .271 .324 .541 .865
Batting #1 66 .242 .311 .576 .887
Batting #2 14 .357 .400 .857 1.257
Batting #3 1 .000 .000 .000 .000
Batting #4 7 .143 .333 .143 .476
Batting #5 52 .269 .296 .577 .873
Batting #6 61 .213 .300 .377 .677
Batting #7 22 .182 .250 .182 .432
Batting #8 4 .500 .500 .500 1.000
Batting #9 52 .308 .321 .500 .821
What does Kepp bring that Frazier trumps?
Veteran presence? Nope
Better career stats? Nope
Better projections for 2012? Depends on what you want? BA and OBP then Keppinger wins
The ability to play multiple positions? Frazier can play the OF but isn't that why we signed Ludwick? And if Cozart goes down for a prolonged period of time I'd rather have Kepp at SS than Frazier.
The only thing I think Frazier has an edge on is that he is younger and cheaper but not better.
I see where your coming from but if I remember correctly janish didnt look that spectacular in the field in the beginning of last year when he was getting most of his playing time. in fact I remember a couple games where he booted some easy balls. He started 80 games last year and played in 103(just at SS) and had 10 Errors. thats not spectacular. that would be 20 errors for the whole season. Omar Vizquel used to play 150 games a year and have only 5 errors for the year. Thats a GREAT defensive SS. He will make the routine play 9/10 times but you never see Janish make the spectacular plays. Alls I'm saying is that hes not as great defensively as everyone seems to think, and IMO thats the misconception. For a guy known for his defense its not as great as it should be. he may have had a nice minor league career defensively but it hasn't totally translated into the show. IMHO Id rather have Theriot thats all. and Theriot isnt known for his defense. the guy can handle a bat
Last edited by DGullett35; 01-19-2012 at 11:47 AM.
I think Janish's bat needs to improve if he's going to stay on the big league roster. His defense is good but not as good as what it is thought to be.
Unless we release/option Janish there is no room on the 25 or 40 man for Theriot or Keppinger. And that's with Frazier starting at AAA.
Keep Ryan Theriot and his -8.5 UZR far away from Cincinnati's left side of the infield. You don't need a good bat in the shortstop position, especially with the weapons the Reds have almost everywhere else on the field. Janish is a GREAT fielder, and if you judge a shortstop by his number of errors, you're severely missing the point. Janish gets to balls that Vizquel, Keppinger, and especially Theriot have no shot at, so he has great value as a late-innings replacement and spot starter. I don't understand people's fascination with losing defensive ability for a little bit of offense at the most important defensive position on the field. Plus, there's a very small chance Janish has the horrid year at the plate he did last year. It'll most likely be somewhere between his last two years. Not good, but not so bad that you can't have him on the roster.
Up until the end of the season who really values late inning defensive replacements until September and the playoffs? Not a lot of teams. Valuing a late inning defensive replacement is like running your offense around the sacrifice bunt. There's no real need for it until playoff time.
My point is, he's not a shortstop. We might as well be talking about signing Carlos Guillen or Aaron Miles to play short. They've done it before; they're just not good at it.
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Adam LaRoche remains unsigned and the Washington Nationals are reportedly getting eager for an answer from their first baseman of the past two seasons, according to The Washington Post.
The Nationals were hoping to have a resolution regarding whether or not LaRoche was signed by the end of the year, according to the newspaper.
General manager Mike Rizzo could press the issue soon, with something close to an ultimatum, the newspaper reports.
LaRoche, 33, has a two-year offer on the table from the Nationals, according to multiple reports. However, he is believed to be seeking a three-year deal.
One factor complicating LaRoche's free agency is the fact that he was extended a qualifying offer, meaning a team must give up its first-round pick (if it's not in the top 10) to sign him.
LaRoche's unresolved status has also complicated Michael Morse's role with the team. If LaRoche returns, Morse could be traded. Without LaRoche, Morse would likely man first base for Nationals.
Last season, the lefty-hitting LaRoche hit a career-best 33 home runs and matched a career-high with 100 RBIs.


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Editor's Note: TheStreet ratings do not represent the views of TheStreet's staff or its contributors. Ratings are established by computer based on metrics for performance (which includes growth, stock performance, efficiency and valuation) and risk (volatility and solvency). Companies with poor cash flow or high debt levels tend to earn lower ratings in our model All three major indices are trading down today with the Dow Jones Industrial Average ( ^DJI) trading down 98 points (-0.7%) at 14,507 as of Friday, April 5, 2013, 12:49 PM ET. The NYSE advances/declines ratio sits at 1,009 issues advancing vs. 1,921 declining with 109 unchanged. The Real Estate industry currently is unchanged today versus the S&P 500, which is down 0.9%. On the negative front, top decliners within the industry include Duke Realty ( DRE), down 1.9%, Jones Lang LaSalle ( JLL), down 1.8%, American Tower ( AMT), down 1.5%, Plum Creek Timber ( PCL), down 1.4% and Brookfield Office Properties ( BPO), down 1.3%. A company within the industry that increased today was Icahn ( IEP), up 1.6%. TheStreet Ratings group would like to highlight 5 stocks pushing the industry lower today: 5. CommonWealth REIT ( CWH) is one of the companies pushing the Real Estate industry lower today. As of noon trading, CommonWealth REIT is down $0.93 (-4.0%) to $22.07 on heavy volume Thus far, 3.7 million shares of CommonWealth REIT exchanged hands as compared to its average daily volume of 3.7 million shares. The stock has ranged in price between $22.07-$22.70 after having opened the day at $22.59 as compared to the previous trading day's close of $23.00. CommonWealth REIT is a real estate investment trust launched and managed by Reit Management & Research LLC. The fund invests in the real estate markets of the United States. It seeks to invest in office buildings, industrial buildings, and leased industrial land. CommonWealth REIT has a market cap of $2.7 billion and is part of the financial sector. The company has a P/E ratio of 64.2, above the S&P 500 P/E ratio of 17.7. Shares are up 45.2% year to date as of the close of trading on Thursday. Currently there are no analysts that rate CommonWealth REIT a buy, no analysts rate it a sell, and 2 rate it a hold. TheStreet Ratings rates CommonWealth REIT as a hold. The company's strengths can be seen in multiple areas, such as its solid stock price performance, revenue growth and reasonable valuation levels. However, as a counter to these strengths, we also find weaknesses including deteriorating net income and poor profit margins. Get the full CommonWealth REIT Ratings Report now. Exclusive Offer: Jim Cramer's 'go-to' small/mid-cap guru Bryan Ashenberg only buys stocks he thinks could return 50-100%. See his top picks for 14-days FREE.
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Captain Marvel was the first comic book superhero to hit the screen.
A lot of people probably don't know that Captain Marvel, originally a comic book character for Fawcett Publications, was the first superhero whose exploits were adapted for the screen, in a Republic Pictures serial from 1941, directed by William Witney (Quentin Tarantino's favorite director) and John English. With an epic running time of 216 minutes, the serial played out in 12 chapters, spread out over 12 Saturday mornings, when it would run as a continuing feature as part of the Saturday matinee program at movie theaters. Serials in the sound era ended production in 1956, and the genre had been around since the silent era, but among serial aficionados, Republic's serials have a special place of pride as being the most slickly produced and directed, with superb special effects by Howard and Theodore Lydecker, and non-stop, pulse pounding action.
As Wikipedia notes of Captain Marvel's genesis and production, the "Adventures of Captain Marvel is a 1941 twelve-chapter film serial directed by John English and William Witney for Republic Pictures, adapted from the popular Captain Marvel comic book character then appearing in Fawcett Comics [. . .] during an archaeological expedition to Siam, the Malcolm Archaelogical Expedition unearths the lost Golden Scorpion, an ancient, multi-lensed statue with a curse attached, which has the power to transmute base metals into gold, but also to destroy those who seek to misuse its power. Billy Batson [Frank Coghlan, Jr.], a young man who has tagged along on the expedition, meets the ancient wizard Shazam, who grants him the power to become Captain Marvel [Tom Tyler] and protect those who may be in danger from the Scorpion's curse.
The lenses from the Golden Scorpion are divided among five scientists of the Expedition, but a black-hooded villain known as the Scorpion then attempts to acquire all of the lenses and the Scorpion device itself. Several expedition members are killed in the Scorpion's quest despite Captain Marvel's continual efforts to thwart him. Deducing that the Scorpion always seems to know what goes on at all the meetings with the scientists, Billy later confides his suspicions to his friends, Betty Wallace [Louise Currie] and Whitey Murphy [William Benedict], that the Scorpion might be one of the archaeological team.
The Scorpion later discovers the connection between Billy and Captain Marvel. After capturing him, the Scorpion interrogates Billy for the secret. Billy transforms into Captain Marvel and reveals the Scorpion to be one of the last surviving scientists, who is then killed by an angry Siamese native. Captain Marvel tosses the scorpion statue into a volcano's molten lava to prevent it from ever being used for evil. Once it is destroyed, Captain Marvel is instantly transformed back into Billy Batson [. . .]
Adventures of Captain Marvel was budgeted at $135,553, although the final negative cost was actually $145,588 (a $10,035, or 7.4%, overspend) — [still a mere $2,330,151.43 in 2012 dollars]. It was filmed between December 23, 1940 and January 30, 1941 under the working title Captain Marvel. The serial was an outgrowth of Republic's failed attempt at a serial which would feature National Periodical Publications [today known as DC Comics]'s Superman. When DC refused to grant Republic the rights to the character, Republic approached Fawcett Comics, and struck a deal to bring Captain Marvel to the screen. Captain Marvel was actually more popular the Superman as a comic book character at the time, outselling Superman by a a considerable margin.
Director William Witney was, however, skeptical about trying to film Captain Marvel after the legal problems with Superman, but the serial went ahead on schedule. DC attempted legal action to prevent the filming, citing Republic's previous attempt at a Superman serial, but was unsuccessful. Adventures of Captain Marvel was a huge success at the box office, and is considered by many to be Republic's finest chapter play of the 66 serials the company produced. About a decade later, following a legal battle with DC and a declining market, Fawcett ceased publication of all its comic series. In the 1970s, the Captain Marvel family of characters was licensed and revived (and ultimately purchased) by DC Comics."
The problem with Republic serials for the contemporary viewer, however, is that almost none of them are available in DVD format. When VHS tapes were first introduced, Republic put out most their serials in excellent two-tape transfers, necessitated by the long running time of each production, but when DVDs were phased in, for some reason, the serials never made the jump to the new format. Happily, Adventures of Captain Marvel is the exception to that rule, and is readily available on a legal DVD from Artisan Releasing and Republic Pictures, in a sparkling transfer.
If you're interested in the history of comic book films, this is indispensable viewing.


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by, 07-04-2013 at 03:19 AM (4413 Views)
Elimination Tornado Tag Team Match For the Tag Team Championships :
KoW (c) Kassius ohno and Antonio Cesaro vs The Usos Vs The Wyatt Familly vs Sami Zayn and Adrian Neville
Would be Awesome!!I mean,Kings of wrestling as champs together vs Pac and Generico vs The Usos vs The Wyatt familly!!Technical Wrestling team vs Powerhouses Vs High Flyers Vs Submissions (They should give the usos some submission moves to get this one ) Pretty much fun on the opening I think!!!
Dean Ambrose Vs Mick Foley in a hardcore match!
Yeah,We lost that feud because of Mick condition,but,what if Mick can get in shape!!This one would elevate Dean carreer the same way it did for Randy and Edge when both fought with Foley!!!A Great hardcore match with Dean as winner would be quite entertaining!
Ryback Vs Matt Sydal !
yes,You've read it right.Ryback vs Matt Sydal,or should I say..EVAN BOURNE!!
Evan Comes back with a totally unexpected gimmick ; Not only he goes back to being called Matt Sydal,but he goes off into an anti management character,who'se getting screwed by the WWE who doesn't want him to compete!!His matches would always end up with him betting his opponent with chairs and stuff,causing DQ,he'll even beat's up officer and Referee out of anger and agony.He will adopt a brian pillman like type of talking/moving too,and then,sneak attack/beat the living hell out of ryback backstage,calling him the management Babyboy,and the guy who took HIS OPPORTUNITY AND HARD WORK,resulting in this match!
Curtis Axel (c) Vs RVD Vs Christian Vs Kane Vs MVP(c) vs Corey Graves ladder match For Both the intercontinental and US Championship :
Would be a good match,replacing the old MITB match!!Corey graves and RVD for crazy spots,Christian and Kane for Getting thrown out of the Ladder into a pills of tables/thrash/ladders,Curtis axel and MVP as champs!
Diva battle royal/Everybody piss breal lol
ADR Vs Jack Swagger 30 minutes ultimate Submission match :
Jack turning face on ADR would finnaly get the gut over!!!And a memorable win at the greatest stage of em all would gives him credibility!!
HHH(With Stephanie) Vs Batista(With VKM) Over the Control of the WWE :
Batista expressed that if he'll comeback to the wwe,he want a great feud with a great wrestler.He said names like HHH,Undertaker and The Rock!!So,a returning batista as HHH friend,then betraying him for Vince mcmahon would make sense!!And,to add the holy shit factor,Batista should win,Vince still rules the WWE!!!
Dolph Ziggler Vs Chris Jericho For the World Heavyweight Championship :
iNStant classic of the night!!Should Be a five star match,considering how much those guys have been attacking each others,even when feuding with someone else they still do it lol!
Randy Orton Vs The Rock :
legend Killer Randy orton vs the Rock would be a greater feud than Cena/Rock.Why?Because watch Randy orton promo against The Rock back in 2004 when he got Rocky thrown out of the Arena with Bischoff help.Heel Randy can be better than Heel Punk,Yes,and deep down,you know it.I hate this Randy orton that we have right now ; Everytime he comes out,I feel offended!I used to like Randy orton who thrash talked Kurt angle like a freaking real ECW Superstar!!The Randy orton who REALLY injured John Cena and got his spotlight!!The Ruthless legend Killer "I AIN'T GONNA SPEND THE WHOLE BLOG TALKING ABOUT HIM" Orton!!He would start the feud by complaining about how he IS the real relevant wrestler and stuff,and punt Kick the Rock,screwing him from having a rematch for the WWE Title!!
Undertaker vs John Cena/Sting for the streak!!
WEll,once again,everybody dream match is staying alive again because of the dirtshit claiming that sting may jump ship to the WWE!!If It Ain't gonna be STing,well,John,You have to loose to Taker at least once at wrestlemania!!!
Brock Lesnar(c) Vs Daniel Bryan Vs CM PUNK For the WWE Championship :
In a Chris Benoit Like moment,Daniel Bryan Make Either Punk Or Lesnar Taps out at the main event,to create one of the most historic moments in wrestlemania and redeem himself from the 18 seconds lose!
Well,that's all folks!I hope you like it!


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New Delhi, Sep 3 (IANS) Forthcoming mythological TV show "Buddha" was initially planned to be a film. Filmmakers Shekhar Kapur and Ashutosh Gowariker had already started developing the script, however, producer B.K. Modi, felt that the TV medium would have a larger scope for such a project.
The show will narrate the life of Gautam Buddha - his life's journey and various teachings.
"The scope of television today is larger than films and we wanted Buddha's story to unfold in all its splendour and reach out to the largest denominator of people possible. Only TV can give us that reach," Modi, who is also the founder and chairman of Spice Group, said in a statement.
"Buddha", which goes on air on Zee TV Sunday, will star established names like Kabir Bedi, Samir Dharmadhikari and Nigaar Z. Khan.
Kabir Bedi makes a comeback on TV after a long break.
"I am playing a sage who foresees the coming of the Buddha," he said.


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Hepatic Safety of Raltegravir Versus Efavirenz as HIV Therapy for Patients With HIV and HCV Coinfection
This study is ongoing, but not recruiting participants.
University of Hawaii
Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam
Viet Tiep General Hospital, Hai Phong, Vietnam
Oxford University Clinical Research Unit, Vietnam
Information provided by (Responsible Party):
University of Hawaii
ClinicalTrials.gov Identifier:
First received: June 16, 2010
Last updated: March 6, 2017
Last verified: March 2017
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- How to Read a Study Record
Detailed Description:
The main objective is to evaluate the hepatic safety of raltegravir when compared to efavirenz, both in combination with tenofovir and emtricitabine as first-line HIV treatment in patients with HIV and hepatitis C coinfection.
|Hepatitis C, Chronic HIV Infection
|Drug: Raltegravir Drug: Efavirenz
|Phase 4
|Study Type:
|Study Design:
|Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
|Official Title:
|Hepatic Safety of Raltegravir-based and Efavirenz-based Antiretroviral Regimens in Antiretroviral-Naïve HIV-infected Subjects Co-Infected With Hepatitis C
Resource links provided by NLM:
MedlinePlus related topics: HIV/AIDS Hepatitis Hepatitis C
Drug Information available for: Efavirenz Raltegravir Raltegravir potassiumU.S. FDA Resources
Further study details as provided by University of Hawaii:
Primary Outcome Measures:
- Rates of Grade 2 and higher alanine aminotransferase (ALT) elevations [ Time Frame: over week 72 ]To estimate the rates of grade 2*and higher ALT elevations in the two regimens.
Secondary Outcome Measures:
- Plasma HIV RNA </= 150 copies/mL by the Abbot M2000 platform [ Time Frame: 24 weeks and 72 weeks ]To estimate rates of HIV virologic suppression at week 24 and week 72
- Change in CD4 count [ Time Frame: from entry to week 24, from entry to week 72 ]To assess changes in CD4 counts from entry to week 24 and week 72
- Time to death and/or occurrence of new or recurrent AIDS-defining events [ Time Frame: entry to week 24, entry to week 72 ]To examine time to death and/or occurrence of new or recurrent AIDS-defining events
- Changes in fasting blood glucose and cholesterol measures [ Time Frame: entry to week 24, entry to week 72 ]To examine changes in fasting blood glucose and cholesterol measures
- Changes in monocyte and T cell immune activation [ Time Frame: entry to week 24, entry to week 48 ]To study changes in levels of immune activation in monocytes and T cells from entry to week 24 and week 72 and assess relationship with clinical, immunological and virological outcomes
- Neurocognitive function [ Time Frame: entry to week 24, entry to week 72 ]To evaluate the neurocognitive function of HIV and hepatitis C (HCV) coinfected subjects undergoing antiretroviral therapy (ART)
|Estimated Enrollment:
|Study Start Date:
|February 2014
|Estimated Study Completion Date:
|June 2017
|Primary Completion Date:
|December 2016 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: Raltegravir based therapy
Emtricitabine/tenofovir DF* 200 mg/300 mg po daily + Raltegravir 400 mg twice daily
Drug: Raltegravir
Emtricitabine/tenofovir DF* 200 mg/300 mg po daily + Raltegravir 400 mg twice daily
Other Name: Isentress
Active Comparator: Efavirenz based therapy
Emtricitabine/tenofovir DF* 200 mg/300 mg po daily + Efavirenz 600 mg po daily
Drug: Efavirenz
Emtricitabine/tenofovir DF* 200 mg/300 mg po daily + Efavirenz 600 mg po daily
Other Name: Sustiva
Detailed Description:
The trial will recruit 80 treatment-naive HIV-infected patients with chronic hepatitis C coinfection from two HIV treatment centers in Vietnam. Patients will be randomized to receive either raltegravir or efavirenz, both in combination of tenofovir and emtricitabine, as first-line HIV therapy over a period of 72 weeks. The primary endpoint is the rate of alanine aminotransferase (ALT) elevation during the 72 week study period. Secondary endpoints include rates of virological suppression, CD4 count change, numbers of AIDS events and death, rates of fasting glucose and cholesterol measures, neurocognitive function and levels of immune activation. Patients will be followed monthly for the first 3 months and every 3 months thereafter. At the end of the trial period, patients will be transferred to the National HIV treatment program for continuation of HIV therapy.
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- HIV infected patients, age >18 years, meet Vietnam guideline to begin ART (CD4 count < 350 cells/mm3 and/or WHO stage III or IV disease)
- Hepatitis C infection as documented by positive HCV antibodies and a detectable serum HCV RNA level
- AST and ALT ≤ 2 x ULN (≤ 80 U/L)
- Estimated creatinine clearance ≥ 60 mL/min
Exclusion Criteria:
- Any prior ART
- Positive Hepatitis B surface antigen
- Clinical evidence of de-compensated cirrhosis (ascites, encephalopathy, esophageal bleeding)
- Requirement for acute therapy for other AIDS-defining illness within 14 days prior to study entry
- Currently on rifampicin therapy
- In the first trimester of pregnancy, intent to become pregnant, or breast feeding during the study period
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01147107
Please refer to this study by its ClinicalTrials.gov identifier: NCT01147107
|Viet Tiep General Hospital
|Hai Phong, Vietnam
|Hospital for Tropical Diseases
|Ho Chi Minh City, Vietnam
Sponsors and Collaborators
University of Hawaii
Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam
Viet Tiep General Hospital, Hai Phong, Vietnam
Oxford University Clinical Research Unit, Vietnam
|Principal Investigator:
|Van Vinh Chau Nguyen, MD, PhD
|Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam
|Principal Investigator:
|Cecilia M Shikuma, M.D.
|University of Hawaii - Hawaii Center for AIDS (HICFA)
|Study Director:
|Thuy Le, M.D.
|University of Hawaii, Oxford University Clinical Research Unit
More Information
Keywords provided by University of Hawaii:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on September 25, 2017
|Responsible Party:
|University of Hawaii
|ClinicalTrials.gov Identifier:
|NCT01147107 History of Changes
|Other Study ID Numbers:
|Study First Received:
|June 16, 2010
|Last Updated:
|March 6, 2017
|Individual Participant Data (IPD) Sharing Statement:
|Plan to Share IPD:
|Plan Description:
|IPD will be shared with other researchers upon request following the publication of the data. Researchers will contact the PI.
Keywords provided by University of Hawaii:
HIV/HCV co-infection
Antiretroviral therapy
Additional relevant MeSH terms:
Hepatitis C
HIV Infections
Hepatitis C, Chronic
Liver Diseases
Digestive System Diseases
Hepatitis, Viral, Human
Virus Diseases
Flaviviridae Infections
RNA Virus Infections
Lentivirus Infections
Retroviridae Infections
Sexually Transmitted Diseases, Viral
Sexually Transmitted Diseases
Immunologic Deficiency Syndromes
Immune System Diseases
Hepatitis, Chronic
Raltegravir Potassium
Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination
Antiviral Agents
Anti-Infective Agents
Reverse Transcriptase Inhibitors
Nucleic Acid Synthesis Inhibitors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Anti-Retroviral Agents
Anti-HIV Agents
ClinicalTrials.gov processed this record on September 25, 2017