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Last week I tweeted that shares of Dunkin' Brands (DNKN) have outperformed Starbucks (SBUX) year-to-date and over the past 52 weeks. The formula for this outperformance is linked to the company's non-stop new-product launches and aggressive new-store rollouts. If Dunkin' can hit its stretch goal of increasing its store count by 5% annually over the next five years, I believe the stock will go much higher.
Dunkin' Brands, which includes Dunkin' Donuts and Baskin-Robbins, is on a roll. On Jan. 31, the company reported full-year 2012 results. During the fourth quarter, same-store sales grew 3.2%. For the year, the company added a staggering 665 new restaurants, including 291 net new Dunkin' Donuts in the U.S. Fiscal 2012 revenue was up 6.1%, net income grew 15.3% and earnings per share rose 38%. Unadjusted operating margins rose 370 basis points to 36.4%. (Adjusted operating margin was 46.3%.) And for the one-year period ending Monday, the stock is up 27%. Holy cow! It's just donuts, coffee and ice cream. You'd think they were making something people need.
One of the keys to Dunkin's success is its customer base, which is distinctly different from Starbucks. Dunkin' really knows its customers and is able to drive same-store sales with a constant stream of product innovations. For example, coffee sales rose because of a slew of new flavored hot and iced espresso beverages. Breakfast, which Starbucks has bungled for years, keeps cooking for Dunkin'. Sales of limited-time-only smoked sausage breakfast sandwiches, bakery sandwiches and K-cup portion packs keeps customers coming back for more. Management is trying the same tricks at Baskin-Robbins, which offered holiday-inspired ice cream flavors such as Pumpkin Pie, Peppermint and Winter White Chocolate. Other limited-time offerings included the Warm Belgian Waffle sundae and a variety of limited-time-only take-home pints and quarts of ice cream. The heavily advertised "limited time-only" offerings may seem like a gimmick, but Dunkin' customers love it.
The other key to Dunkin's performance comes from its aggressive new restaurant development. Wall Street loves new store growth and Dunkin' has big plans to blanket the world with coffee and ice cream stores. While it does own and operate a few restaurants, Dunkin' franchisees are doing the heavy lifting. To get to 15,000 locations from 7,000 in the next five years, Dunkin' has focused on brand building and franchisee profitability. The company's long-term goal is to be 100% franchised.
By focusing on national advertising and brand building in parts of the country that do not have many locations, Dunkin' has been able to drive brand awareness, which has led to a frenzy of new store openings. With the cost of building a new restaurant between $460,000 and $470,000, franchisees are always looking to latch on to a profitable concept. (The average location does $858,000 in revenue.) But expanding its reach west is only one part of the equation. Dunkin' has been very successfully opening new stores in emerging markets, like Korea, the Middle East, China, India and Vietnam. Baskin-Robbins has even started expansion plans for Ecuador and Indonesia. Seems no place is too emerging for Dunkin'.
The company recently announced plans to make a major push west. It plans to enter the Southern California market by opening between 330 and 360 new locations. Globally, Dunkin' plans to open between 700 and 860 new restaurants in 2013.
Wall Street forecasts fiscal 2013 revenue of $713 million and earnings of $1.52 per share. I believe DNKN shares will go higher as the company turns coffee, donuts and ice cream into a monster momentum story. Just the push to build new locations out west should move the stock to the low $40s from its current price around $36.


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The Energy - Future Process Control's Role
Find out about the zero energy home of the future and the hydrogen economy. What are the potentials of process control in wind, ocean wave, and geothermal energy systems.
By Béla Lipták
A hundred years ago, only 3% of homes had electricity. It is probable that 100 years from now, 97% of us will live in "zero energy" homes, and only 3% will depend on receiving fuel and energy from the outside.
In the previous parts of this series, I discussed the abundant availability of clean and inexhaustible solar energy. I also noted that process control can double the efficiency of solar collection (from 14% to over 30%) by following the sun and focusing the collected energy onto a stationary solar converter. Before proceeding to the discussion of the "zero energy home of the future" and the hydrogen economy, one should also mention the potentials of process control in wind, ocean wave, and geothermal energy systems.
Wind Turbines
Down on the wind farm
In many locations, the electricity generated by wind farms, is already cost competitive
In May 2007, the National Academy of Sciences released a study indicating that wind turbines could reduce the nation's carbon dioxide generation by 4.5% by 2025. Between 2000 and 2006, the electricity generated by wind farms quadrupled, but the energy generated by them still corresponds to less than 1% of the total national consumption. The U.S. Department of Energy estimates that, in the next 15 years, the combined capacity of wind generators will reach from 19 gW to 72 gW, which corresponds to 2% to 7% of the national electricity generating capacity. According to a European estimate, if fully exploited, Europe could meet 30% of its electricity needs by wind power.
In fact, wind turbine-generated electricity already is cost competitive. It's in the range of 4-6 cents/kWh and dropping, while the average electricity cost from the power companies is about 12 cents/kWh. In many parts of the world, government support is available to finance wind turbine installations. In California, for example, a $32,000 wind turbine (about 12 ft. in diameter and 30-100 ft. tall) is supported by a $16,000 state rebate. The generating capacity of the average wind turbine in the U.S. is 2 kW to 10 kW, and the federal government is considering supporting their use with a one-time credit of $3,000/kW.
In addition, in many locations, the excess electricity that wind turbines generate is accepted by power companies on a "net metering" basis, in which meters "run backwards" when the excess electricity is sent into the grid. The turbines are sized so the accumulation of this excess will compensate for (or exceed) the amount of electricity needed when there is no wind.
In order to meet wilderness preservation considerations, it's suggested that birds, bats, and other animals can be protected, if larger, more slowly rotating blades are used. To meet objections to wind turbines from an aesthetic point of view, artists are coming up with a variety of visually pleasing shape and color combinations.
Ocean Wave Energy
Wave power
Ocean wave energy collection design.
Another renewable energy source is ocean wave energy. It's been studied for nearly four decades, but it's exploitation is just beginning. Dr. Tom Thorpe of ETSU says the highest energy waves are concentrated off the western coasts in the 40o to 60o latitude range north and south.
The power in the wave fronts varies in these areas is between 30 kW/m and 70 kW/m, with peaks up to 100 kW/m in the Atlantic southwest of Ireland, the Southern Ocean, and off Cape Horn. If this energy resource were harnessed, it could meet 10% of the global electricity demand.
Some of the ocean wave energy collector designs are shown in Figure 2. On the top left of the figure is the "Tapered Channel" design. Here, the waves enter a raised lagoon through a converging inclined channel from which the water returns through a turbine generator back into the ocean. On the top right, the oscillating or assisted water column (OWC) is shown. In that collector design, the energy of the ocean waves is used to pump air through an air turbine generator.
On the lower left of Figure 2, the energy of the incident waves act upon a pivoted pendulum (the "pendulor"), and this energy is used to drive a hydraulic pump. On the bottom right, the collector is a heaving buoy device. Here a hose-pump is operated by the force developed between a float and a reaction plate as the energy of the pumped water is converted to electricity.
A more recent design is the Pelamis Wave Energy Converter from Ocean Power Delivery Ltd. The pelamis (named after a sea snake), which is under development in Scotland, is a series of cylindrical segments connected by hinged joints. As waves run down the length of the device, they move the joints, and the hydraulic cylinders incorporated in the joints pump oil to drive a hydraulic motor by means of an energy-smoothing system. Electricity generated in each joint is transmitted to shore by a common sub-sea cable. The planned slack-moored device will be about 130 m long and 3.5 m in diameter. The full-scale version will have a continuously rated power output of 0.75 mW.
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subset: commoncrawl


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ENGLEWOOD, Colo. - Sports Authority has announced a partnership with ShopRunner (http://www.shoprunner.com), a members-only online shopping program that offers consumers unlimited, free two-day shipping with no minimum order size, and free shipping on returns, across a wide selection of retailers.
"We see ShopRunner as an exciting component of our progressive marketing strategy," said Clay Cowan, VP e-commerce with Sports Authority. "In an era when consumers are driving how and when goods are sold, we can leverage ShopRunner's fast, free shipping as an ideal addition to our online shopping experience. We feel that the ability to provide free two-day shipping over the course of a year will be a real value to our consumers who continue to choose Sports Authority across more and more seasons."


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Bob's 84th birthday party! We'll have cupcakes and live music to celebrate our founder's 84th year. There will be special gifts for the first 500 guests. Come have lunch and stay for the party.
Friday, February 15th, 2013 from noon to 2 pm.
Bob's Red Mill Whole Grain Store
5000 SE International Way
Milwaukie, OR 97222
Map & Directions


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Hello Guys,
I'm newbie in programming language & want to learn some programming language.. According to you guys, which programming language is easy now C or C++??? Share some opinions about both languages... __________________________________
Career Magazine
There are plenty of opinions about that on these forums already.
Also, why only choosing between C or C++? The majority on these forums will probably recommend you to start with something like Python. And unless you can find yourself a REALLY decent tutor/tutorials, I would recommend the same, else you'll just get very confused.
c is easier.
C can be completely understood by a mortal.
C++ isn't easier, but if you get used to using the string class and the STL, you can save time and write safer code. I would also recommend another language like python if it's your first language.
c++ is just c with more features, i recommend using c++ but not using classes, your first time.
use structs for data and procedures for code... grouping them together into objects can just end up locking you out of your own program.
What rouncer said.


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Roy earned his baccalaureate degree from UNK and his master's degree from Regis University. He is entering his fifth year of service at UNK, where his primary responsibilities involve treatment of athletic injuries among football players and wrestlers. "Each person brings a unique background and story to our campus," Roy says, "and each injury is unique. The opportunity to provide hope, perspective, guidance, and physical treatment is an incredible challenge and the most rewarding part of my job." He has also enjoyed working with outstanding athletes: Olympic wrestler Tervel Dlagnev (tur-velle duh-lag-nev), for example, and UNK's 2008 and 2012 national champion wrestling teams. He also served as the medical director for the 2007 and 2011 NCAA Division II National Wrestling Championships hosted by UNK. This past year Roy was certified by the National Academy of Sports Medicine as a Performance Enhancement Specialist and a Corrective Exercise Specialist. This has allowed him to assume the role of Rehabilitation Coordinator for the department.
Charles Bicak, Sr. Vice Chancellor for Academic & Student Affairs; Dee Stutz, wife; Recipient-Roy Stutz, UNK Assistant Athletic Trainer; Regent Deter
At the 2012 high school cross country championships in Kearney, spectators took notice as Roy aided a runner who was injured in a fall. "The UNK sports medicine department has made it a priority to treat every person that walks through our doors with the highest quality of medical care we can provide," he says. "Physically, emotionally, spiritually, their needs are our priority and it is our goal to meet them where they are and, hopefully, have a positive impact on their lives."
Roy and his wife, Dee, have two children, Dawson, 9, and Eliza, 5. Dee is with us today. Congratulations, Roy. Your commitment is inspiring and your work on behalf of UNK student athletes is admirable.


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In his State of the Union address Tuesday night, President Obama is bound to splice his progressive Inauguration Day themes with budget and economic messages that finally respond to more prominent issues. These will touch on the need to head off the March 1 budget sequester, in addition to talk on immigration reform, gun control and climate change. The speech will also likely address the need to forge a "balanced" deficit reduction deal, while stepping up investments and reforms designed to protect the middle class, such as curbing college costs and expanding mortgage-refinance assistance.
To quickly address immigration reform, Obama will seize the partisan advantage he helped to create for fellow Hill Democrats with his strong showing among Hispanic voters last November. Should investors wake up Wednesday morning with the notion that the time is "now" for immigration reform in Washington, we'd suggest looking at the money transmitters -- Western Union (WU) and MoneyGram (MGI). In the past, conventional wisdom has expected the deportation of resident illegal immigrants, which can disrupt the flow of remittances back to Mexico and other countries -- bread and butter for companies like these.
On climate change, there's been chatter that Obama might reference an evolving initiative at the Environmental Protection Agency -- one that would create efficiency standards for power plants that's similar to its corporate average fuel economy (CAFE) standards on auto fuel and mileage. But, regardless of how he casts his regulatory objectives, it's likely to reinforce the notion that coal-fired power plants will face increasing pushback and pressure, and that the result will hurt both coal producers -- Arch Coal (ACI) and Peabody (BTU) -- as well as dependent utilities American Electric Power (AEP) and First Energy (FE).
How to view any reflexive negative reaction? My partner Jim Lucier would note that EPA can move forward, but only slowly, as "a boa constricter strangling its prey." For this reason, there could be interim value among the coal names for the brave of heart. Meanwhile, he'd see continued confirmation of the bullish natural gas story, for recently troubled Chesapeake (CHK), as well as Devon (DVN), EOG Resources (EOG) and Anadarko (APC).
On gun control, my colleague Loren Smith sees just a 30% prospect of significant changes to the gun laws (e.g., a restored ban on assault weapons). Nevertheless, he observes that expanded background checks and more stringent regulation of firearms dealers seem more likely. Enactment of any such changes could squeeze private sales and smaller dealers -- while benefiting larger retailers such as Cabela's (CAB), Dick's (DKS) and Wal-Mart (WMT). Meanwhile, there is at least some possibility that Stratasys (SSYS) could be affected by concerns over use of 3D printers to manufacture firearms.
Moving to higher education, Obama will talk about the need to curb tuition increases and student-loan interest rates -- which, as of last summer, are scheduled to double by July. By this point, much of the assault against the for-profit schools has run its course, and Republicans seem resolved to extend the outcomes-based focus to not-for-profit colleges. So this should bring a measure of relief to the embattled for-profit industry and their lobbyists. As a result, if we see any negative reaction toward such names as Apollo Group (APOL), Strayer (STRA), DeVry (DV), Capella (CPLA) and ITT Educational (ESI), it could mean a bottoming.
Meanwhile, the lenders continue to have their own attractive stories -- in part politically immunized by the March 2010 repeal of the former FFELP student loan program. In my view, that's particularly relevant for industry leader Sallie Mae (SLM).
As for homebuilders and mortgage companies, Obama is expected to strike a blow for new Hill proposals to help current but underwater borrowers refinance into Fannie Mae and Freddie Mac loans. While the legislation faces an uphill battle, outsized winners here might be midsized banks that would gain underwriting parity with the big guys. These could include SunTrust (STI), U.S. Bancorp (USB) and BB&T (BBT). Meanwhile, homebuilders -- including Pulte (PHM), Ryan Homes (NVR), Toll Brothers (TOL), KB Home (KBH) and Lennar (LEN) -- would only continue to benefit from a housing market recovery, enhanced by partial relief for some 11 million borrowers who are precariously perched just one bad economic event away from delinquency or default.
Regarding an across-the-board sequester, for months my uber-analyst colleague Byron Callan has written that investors have refused to discount the 9% across-the-board and other budget authority cuts that now seem unavoidable. That began to change at the beginning of the year, but sanguine expectations persist. Should we see investors' faith shaken in such rationality, Byron says look out for softness in L-3 Communications (LLL), Northrop Grumman (NOC), SAIC (SAI) and Huntington Ingalls (HII), in particular.
Non-defense discretionary programs will take a hit as well, although it'll be smaller (5.1%) because of a buffer created by a 2% cut to Medicare providers. Rob Smith of Capital Alpha warns of pain in pure play names dependent upon grants from the National Institute of Health -- genetic analysis/medical tools companies such as Illumina (ILMN), Life Technologies (LIFE) and Pacific Biosciences (PACB).
As for that hit to Medicare providers, it will hardly be painless for hospital companies such as Health South (HLS), HCA (HCA) and Tenet (THC). Nevertheless, as Kim Monk points out, the industry is trying to put the best face on it, suggesting that a sequester might shield them from deeper cuts within the context of a broader budget deal this summer or fall. This spin may or may not provide insulation as investors react to Obama's address. But, regardless, Kim warns that the industry is just as likely to have to give twice -- so the sanguine story about the sequester is hardly assured of proving true.


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Can I Mix a Static With a Dynamic Rope for Rappelling?
Can you tie a static rope to a dynamic rope and rappel safely? If we do a big wall, we will have one of each and in the event of rappelling, need to know if this is safe. Also, what about two dynamic ropes of different diameters, say a 10.5mm and 9.8mm?
It is good that you have a goal, because now you have purpose, that is, you want to stay alive. I especially like your goal because you wrote it down, a written goal represents a real commitment. Your goal also fulfills all the basic tenets of a good goal. It is conceivable, controllable and measurable. All too many times I hear of goals, such as I want to cure Dengue Fever! that are just stupidly unrealistic. You don't, however, need to get too safety crazy because the world will end on 2012 when the Mayan calendar runs out after being in play for over 2,000 years. Let's just keep you going until then and let the cards fall where they may after that.
Know that even in the best circumstances, rappelling is never safe and is the number four killer of climbers, experienced and novice alike. Of course, it is conceivable that you can rappel on a static and dynamic cord and survive, but you must know a thing or two about those ropes. A dynamic rope pared with a static rope (and two dynamic ropes of dissimilar diameters such as your 10.5mm and 9.8mm) could, due to their differing rates of stretch and friction, cause the knot joining the ropes to creep at the anchor. Result? The rope ends get uneven and you will hit the end of one before the other, moving rappelling from being the number four killer to the number three killer. Even if you survive, you'll have a hard time gripping the ropes, because one will speed through your hand and the other won't.
To control your goal, i.e., to rappel co-joined static and dynamic ropes (or two dynamic ropes of very different diameters) and live, you must knot the ends of both ropes! Also, place the knot joining the ropes on the same side of the anchor as the dynamic (or smaller diameter) rope. Rigged this way, the knot will jam against the anchor when the ropes attempt to shift, keeping the ends even. Be aware that the knot might pull through the anchor or jam into it and stick, making retrieval difficult.
Now for the measurable part. If, after completing your rappel, you find yourself at a banquet table and Warren Harding passes you a goat-skin bota of Beaujolais, don't fret, you can't attain every goal. Gear Guy has spoken!
GOT A QUESTION? E-mail Gear Guy! email@example.com


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Mail: Southern statutes symbolize suppession
Mail: Thanks for helping Aiden
More opinion
Robertson and Delsing re-elected chair, vice chair of NWB
Goat Expo set first October weekend
More Ag News
Dan Mauk was elected chairman Monday of the North Platte Housing Authority.
Mauk will lead the efforts of the five-member board of the directors, comprised of former chairwoman Carolyn Trujillo, Rick Kolkman, Savanah Sellers, Lawrence Ostendorf and Mauk.
The North Platte Housing Authority oversees operations at Autumn Park, a retirement complex in the 700 block of W. Philip, as well as 150 low-income residences scattered around the city.
The authority is funded by the U.S. Department of Housing and Urban Development.
The Housing Authority has about $1.4 million in cash reserves and operates on a yearly grant from HUD of about a half-million dollars, Mauk told the Bulletin.
But last spring, the HUD money did not arrive, and the board agreed Monday to join other housing authorities in a lawsuit to pursue their annual grant money.
Mauk said the outlook is that less federal money will be given to local housing authorities, due to the size of the national debt. The board is in the process of strategic planning, considering ways to provide housing with less money.
The planning will continue to the end of the year, Executive Director Ed Greenwood said.
Were in the middle of (it), Greenwood said, during which a lot of ideas are thrown out and discussed.
One idea is to sell some of the scattered site houses and reinvest in other housing projects in town, but discussions are strictly preliminary, Mauk and Greenwood both said.
We may have to learn how to be a quasi-for-profit agency, Mauk said. We are trying to figure out strategies to provide safe, efficient, well-maintained residences for the elderly, our primary population, and be of short-term help for able-bodied but economically challenged families.
Most of the scattered site homes were built in the 1970s, are well-maintained and will be useable long into the future, Mauk said.
Both Mauk and Greenwood said public comments will be solicited when long-range plans become more definite, which could happen by the end of the year.
A good number of scattered roofs were damaged by hail during the spring, and some asphalt driveways are deteriorating badly with age, Greenwood said.
Repairs are being made, he said.
Flatrock Publishing, Inc.
1300 E 4th St., Suite F
North Platte, NE 69101


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On Saturday, January 15, Bullitt East High School archery team hosted an invitational tournament. This was a very large undertaking and required the help of many parents and volunteers. Special thanks to Coach Cindy Allen for her numerous hours of preparation in addition to a very long tournament day as well as thanks to Assistant Coach Kevin Gabbert for his many hours of instruction for the team and all his help with this tournament.
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The centerpiece it does involve, I'm informed, is Chris Kaman. Now that Marcus Camby (double-figure rebounding last two games) is nearing full strength, the 1-6 Clippers are open to a rational market trade for the big guy who has battened down their middle for five seasons and is owed $43 million over four seasons.
I doubt that we make muscle up a trade that wouldnt involve Granger or Dunleavy, but I would love Kaman here. Good passer, and has some nice post moves. I think a future of Kaman and Hibbert as our big men would be nice
I'd definately do Dunleavy for Kaman. Give us a player for a position we're pretty weak at http://games.espn.go.com/nba/feature...2~11&te=&cash=


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A Study of ddI in Children With AIDS Who Have Not Had Success With Zidovudine
This study has been completed.
Bristol-Myers Squibb
Information provided by:
Bristol-Myers Squibb
ClinicalTrials.gov Identifier:
First received: November 2, 1999
Last updated: August 4, 2011
Last verified: August 2011
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
The purpose of this study is to make didanosine (ddI) available to children with AIDS who are clinically deteriorating on zidovudine (AZT) or intolerant to AZT and cannot enter the Phase II ddI programs due to protocol exclusion or geographic location.
|HIV Infections
|Drug: Didanosine
|Study Type:
|Study Design:
|Masking: None (Open Label)
Primary Purpose: Treatment
|Official Title:
|An Open Label Study Regimen of Videx (2',3'-Dideoxyinosine, ddI) in Children With Acquired Immunodeficiency Syndrome (AIDS) Who Have Demonstrated Significant Deterioration or Intolerance to Zidovudine (Retrovir)
Resource links provided by NLM:
MedlinePlus related topics: HIV/AIDS
Drug Information available for: Zidovudine DidanosineU.S. FDA Resources
Further study details as provided by Bristol-Myers Squibb:
|Ages Eligible for Study:
|3 Months to 12 Years (Child)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria
Concurrent Medication:
- Concomitant medications for the treatment of complications of AIDS.
- Concomitant use of ddI with the following drugs must be done with extreme caution:
- Other nucleosides (e.g., ganciclovir).
- Drugs with toxicities similar to those observed with ddI (e.g., phenytoin).
- Drugs with significant pancreatic toxicities, including many drugs used for treatment of major opportunistic infections.
- Use of Sulfonamides or intravenous pentamidine for treatment of acute Pneumocystis carinii pneumonia (PCP) requires discontinuation of ddI for a week following treatment of PCP.
- Caution should also be exercised with patients having intractable diarrhea or patients following a low sodium diet.
Patients must have the following:
- Diagnosis of AIDS. Demonstrated either significant deterioration despite parenteral dosing with zidovudine (AZT) or significant intolerance to AZT.
Signed informed consent by parent or legal guardian. Evaluations every 7-14 days while taking ddI for the first 4 months. Monthly follow-up is required thereafter.
Exclusion Criteria
Co-existing Condition:
Patients with the following conditions or symptoms are excluded:
- Acute pancreatitis or any history of pancreatitis.
- Seizures or a history of seizure disorder.
- Grade I or greater peripheral neuropathy.
- Preexisting cardiomyopathy.
Concurrent Medication:
- Zidovudine (AZT).
- Chemotherapy with cytotoxic agents.
- Those agents that may cause pancreatitis such as:
- Pentamidine.
- Sulfonamides.
- Antituberculosis drugs.
- Cimetidine.
- Ranitidine.
- Corticosteroids.
- NOTE the cautionary statement in Patient Inclusion Concurrent Medication.
Patients with the following are excluded:
- Acute pancreatitis or any history of pancreatitis.
- Seizures or a history of seizure disorder.
- Grade I or greater peripheral neuropathy.
- Preexisting cardiomyopathy.
Prior Medication:
Excluded within 15 days of study entry:
- Any anti-retroviral except zidovudine (AZT).
- Zidovudine (AZT).
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00002280
Please refer to this study by its ClinicalTrials.gov identifier: NCT00002280
|United States, Connecticut
|Bristol - Myers Squibb Co
|Wallingford, Connecticut, United States, 064927600
Sponsors and Collaborators
Bristol-Myers Squibb
|Study Director:
|Bristol-Myers Squibb
|Bristol-Myers Squibb
More Information
Additional Information:
Keywords provided by Bristol-Myers Squibb:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on September 25, 2017
Additional Information:
|Responsible Party:
|Study Director, Bristol-Myers Squibb
|ClinicalTrials.gov Identifier:
|NCT00002280 History of Changes
|Other Study ID Numbers:
|Study First Received:
|November 2, 1999
|Last Updated:
|August 4, 2011
Keywords provided by Bristol-Myers Squibb:
Drugs, Investigational
Acquired Immunodeficiency Syndrome
Additional relevant MeSH terms:
HIV Infections
Immunologic Deficiency Syndromes
Acquired Immunodeficiency Syndrome
Lentivirus Infections
Retroviridae Infections
RNA Virus Infections
Virus Diseases
Sexually Transmitted Diseases, Viral
Sexually Transmitted Diseases
Immune System Diseases
Slow Virus Diseases
Molecular Mechanisms of Pharmacological Action
Reverse Transcriptase Inhibitors
Nucleic Acid Synthesis Inhibitors
Enzyme Inhibitors
Anti-Retroviral Agents
Antiviral Agents
Anti-Infective Agents
Anti-HIV Agents
ClinicalTrials.gov processed this record on September 25, 2017


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There exists a growing body of scientific evidence suggesting that ideologically committed voters almost encourage dishonesty. A study by Duke University behavioral economist Dan Ariely found that "participants who were planning to vote Democratic indicated that Romney should be held to a fairly high ethical standard [while] Republican participants held a similar standard for Obama."
In this miasma of misinformation, Americans throw open their arms, embracing their own party's political deceptions as the best route towards toward policies they think will benefit them. Take a look at the Facebook pages and Twitter feeds of politically engaged friends. You'll likely come across dozens of links highlighting an egregious political lie, but good luck finding a friend who highlights whoppers from both parties. And even if political lying is unevenly distributed by ideology, as is often claimed, we could expect examples of outrageous dishonesty from their own side, just far fewer.
Because many pundits saw a second Obama term as a particularly high-stakes moment in American political history, the parallel perception has emerged that ours is a particularly dark time for political "truth." It isn't. Throughout history, presidential campaigns have been consistently dishonest. But let us be clear who the guilty parties are: the lying politicians and the voters who love them.


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2 Korg iElectribe Loops by thingstocome
Funkbox iPad -TR-808 Loop by thingstocome
So I've had my iPad for about a week and I can say it actually is a very different experience than the iPhone. Case in point the are drum machine Apps above. Funkbox on the iPhone is ok but I never really used it past a novelty show off item. On the iPad I can sit comfortably and knock out loops with pleasure. The iElectribe really knocks you out. It feels like hardware. Fanboyism aside if you have not had a chance to play with these and you make electronic music go do so.
Is it real or Memorex?
For more info: Funkbox and iElectribe.


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Blog Wars Episode 5: Top 5 Ladder/TLC Matches in Wrestling History
by, 12-01-2011 at 11:43 AM (4283 Views)
Welcome to the 5th episode of Blog Wars. This week The Hit Man will defend against The_Crippler. So let's see the list
Top 5 Ladder/TLC Matches
In honor of TLC the contestants will pick the best Ladder or TLC matches in history based on what they think is important.
I Know that the Hardys, E&C and Dudleys had 3 amazing TLC matches but in this Blog im only gonna include 1. same goes for every match on here, I'm not gonna include 2 matches with the same people on this list. Such as HBK vs Razor Ramon in WM10 and SummerSlam 95. I will include one of there matches and the TLC matches between Hardys, Dudleys and E&C are so close in quality im gonna only choose one. so lets get to the List.
5. Rock vs HHH SummerSlam 1998 IC title
This match was The Rocks Comming out party.... When a Wrestler has a successful run with the Intercontinental Championship, The WWF/WWE gives them a opportunity to show they belong in the Main events and Contend for the World title by losing the Intercontinental Championship to the number one contender in a History making match. Few superstars get this opportunity and fewer succeed. very few such as Randy Savage (Ricky Steamboat WM 3), Bret Hart (Bulldog SS92), Shawn Michaels (WM10 ladder match Razor Ramon) and The man who probably became the biggest star out of all these men "The Rock" in this very match.... this match is over looked cause of there Awesome 2000 feud but the Nation vs DX feud was a intense feud that made both the Rock and HHH, who are now legends.
The match it self was the finsih of the long standing faction blood war between The Nation and DX. It had intensity, Sports entertainment elements and it has history.... This match still holds up as one of the best singles ladder matches and it is 13 years old.
4. Wrestlemania 21 Money in the Bank
This match gets over looked cause Wrestlemania 21 is remembered Cena and Batista being elevated to legit main eventers and become the 2 men to carry the company and the legendary Kurt Angle vs Shawn Michaels match. but for me this is the match of the night.
This match doesnt get the Respect it deserves, This is by far the best MITB match and one of the greatest ladder matches I ever seen... No Money in the Bank since has been able to duplicate the talent involved (Jericho, Christian, Chris Benoit, Edge, Shelton Benjamin, and Kane) in the first MITB. a Must See. Benoits selling in this match is top Notch
3. Chris Benoit vs Chris Jericho RR 2001 Ladder match, IC Championship
This is my favorite Ladder match, It had a realism that non of the other ladder matches had, It wasnt guys obviuosly setting up spots. This was a hard hitting, in your face, Intense Brawl that was off the charts.
If you havent seen this match recently, PLEASE WATCH.
2. TLC Wrestlemania 17
This was for the Tag Team Championship. It was a rematch from WM16 the year before and SummerSlam 2000.... People call this a spotfest but what people dont understand this is The Best Spotfest you will ever see. There is sureal moment afet moment in this match... Sure its a little dated now but WOW this match will blow you away. The Edge Spear off the ladder to Jeff hardy was a Great moment... To me this was the best of the bunch, not much better than summerslam but in my eyes slightly better cause it is Wrestlemania and a few spots that came together really well makes this my favorite of the 3 TLC matches with these men.
1. Shawn Michaels vs Razor Ramon Wrestlemania 10
I know its cliche to pick this match but Honestly this is the standered for a ladder match. it had alot of psycolgy in this match. Michaels was the inovator, if the first Ladder match in WWF happened with another man in it besides Michaels then they would be no MITB, No TLC and No Ladder match cause it would of failed. It was a gutsy performance by both men in this match and being almost 17 years old and still is a awesome match by todays standereds, That you have to give credit to.
Honorable Mentions
TLC3 on Smackdown for the Tag Titles
Hadys vs E&C
Michaels vs Jericho No Mercy
The Hit Man (C)
5. SummerSlam 2009: Jeff Hardy vs CM Punk TLC Match World Heavyweight Championship
Some great spots in this one with both men crashing through a table. Hardy reversing Punk's GTS into a sunset flip off the ladder to CM Punk superplexing Hardy onto the ladder. Towards the end of the match, the spot that defined the match came. Hardy's 20ft Swanton Bomb through Punk and the announce table. This match was the culmination of a very personal fued which blurred the lines of reality and script. The ending to this match captured the essence of this whole fued. It turned out that Hardy's 'Living for the Moment' cost him the match and his World Heavyweight Championship as Punk was the man who recovered from the Swantom quicker and grabbed the title for the victory.
4. One Night Stand 2008: The Undertaker vs Edge TLC Match World Heavyweight Championship
For me this is the greatest one on one Ladder/TLC match. You have the greatest competitor in TLC matches, Edge against the man who has competed in every match possible apart from TLC, The Undertaker. Not only was this match for the World Heavyweight Championship but Taker's career was on the line so a certain emotional aspect was added to this already intense fued. The match started off evenly with both men falling off the ladder and tasting another ladder placed on the turnbuckle. Taker delivered a chokeslam onto the ladder outside to give him the advantage. Ryder and Hawkins both received chokeslams through tables for their interference. The first great spot of the match occurred when Edge took a Last Ride off the ladder and through 2 stacked up tables. The coast seemed clear for Taker but further interference gave Edge enough time to recover and push Taker off the ladder, crashing through 4 tables for the second great spot and to finish off the match.
3. WrestleMania 2000: Dudley Boyz vs Hardy Boyz vs Edge & Christian Triangle Ladder Match World Tag Team Championship
This was the first instalment of the trilogy and was the catalyst to the incarnation of the TLC Match. After all the ladder spots, the Dudleyz were left standing and out came the tables! Devon and Matt were the first to go though the tables but the best was yet to come. Out came a gigantic ladder and the rest is history. Voted the most iconic moment in Wrestlemania history by WWE.com viewers, the world witnessed Jeff take a death defying Swantom through Bubba and the table. The ending to this match is perfect. Matt is only a second away from grabbing the titles but Edge comes from behind and pushes him off the tables perched upon the two ladders through another table, leaving E&C to stand on the table as the victors of the Ladder Match that all other Ladder Matches aspire to be.
2. SummerSlam 2000: Dudley Boyz vs Hardy Boyz vs E&C TLC Match World Tag Team Championship
This was the first ever TLC Match and it did not disappoint! This was the teams' second match together and they capitalised on the success of their previous encounter. The beauty of this match was that each team had their own speciality of weapon in the match. There was more crashing through tables and chair swinging than ever before. The first casualty was Jeff as Bubba was able to dodge the Swantom off the ladder, sending Jeff through 2 tables. Bubba was next as he took the biggest bump, going through 4 tables! Matt looked good for the win until Devon sent him backwards off the ladder and into another 2 tables. Jeff and Devon dangled above the ring with both men eventually dropping to the ground, allowing E&C to get their second win against the Dudleyz and Hardyz.
1. WrestleMania X-Seven: Dudley Boyz vs Hardy Boyz vs E&C TLC Match World Tag Team Championship
Very rarely is the sequel better than the original but TLC was an exception. Voted by IGN as the fifth best WrestleMania and PWI's 2001 match of the year, it's clear to see why this match is top of my list. A great spot half way through the match is when all 6 men are on top of 3 ladders and eventually all 6 men are sent crashing to the ground. A whole rivalry illustrated in one moment! The inclusion of the teams' associates gave depth to the story these teams told. Among all of the spots that took place, 3 stood out. Jeff's Swantom on Spike and Rhyno, Edge's spear on Jeff and Matt and Bubba crashing through the 4 tables. Again E&C won the match but at the end of the day, all 3 teams succeeded in cementing their legacies not only as great tag teams but pioneers of the TLC Match. If I had to show one match to a non wrestling fan, this would be the one. I tried my best to only include one of these matches but the trilogy of matches these 3 teams gave us are head and shoulders above any other Ladder/TLC Match we have ever seen.
Please Vote in the comment sections


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How can a dairy farm family actually work together each day, but really never communicate with each other? It's actually easy to do.
Juggling the demands of a dairy farm, family and personal needs can become quite a challenge. People get so wrapped up in their own problems that they fail to communicate effectively with others. The result is that everyone is talking to each other, but no one is really listening. Then, misunderstandings quickly surface, causing conflict within the family and potential problems with your dairy's profitability.
Avoid these barriers
Some people are simply reluctant to share their inner feelings and emotions with others. They want to keep their thoughts private. In other words, "No one needs to know how I actually feel about this. By sharing my true feelings, I might have to admit I was wrong." To some individuals, saying "I'm sorry" is a sign of personal weakness. Their strategy is to appear being strong by never revealing their true feelings with others.
Meanwhile, other individuals try to gain control by dominating the conversation. They never give the other person a chance to talk. That way, things always work out as they want. They spend little time listening since they are so busy or wrapped up in their own needs and self-interests.
There is a definite lack of respect and trust in some family and employee relationships. Without trust and respect, it is extremely difficult to talk through problems or conflicts in a positive and productive manner.
Take time off
A lack of time off and vacation time for family members can be another pitfall. Family members become too closely tied to the working demands and stress of the dairy. With no opportunity to relax, and little personal time for spouse and family, this quickly adds to the stress and endless pressure of a dairy farm. This can also lead to martial problems.
Failure to keep personal lifestyles between family members out of the dairy operation itself is another pitfall to avoid. The trick is to manage the dairy farm as a business and keep any personal differences out of the family operation.
Meet regularly
I strongly encourage farm families to implement routine family business meetings to prevent these communication breakdowns and to develop a more effective communication process.
Try these ideas to get you started, or back on track.
- Set a specific date, like first Monday of each month, so that family meetings are held on a regular basis.
- Conduct the meeting on neutral or friendly territory.
- Establish an agenda so that each meeting has a specific purpose.Identify the needed reports to be presented. Provide time for open discussion of ideas. Allow suggestions to be shared.
- Establish ground rules ahead of time. (Who chairs each session? How are ideas to be agreed upon or voted on? How are any business disagreements to be resolved?)
- Conduct each meeting on a business-like basis. Develop an attitude of professionalism and use proper business etiquette.
- Keep a record of all business decisions discussed and agreed upon.
- Set aside one meeting a year to establish both family and business goals for the next year. Review goals from the previous year. Remember, both farm and family priorities need to be identified. These priorities create a vision for working together to achieve the common goals set forth by their dairy farming operation. Does your family have a mission statement?
Implementing family business meetings on a regular basis improves family communications and reinforces the feeling that the family farm is a team effort among all family members. It also eliminates any surprises among family members by keeping everyone involved and better informed and helps to keep the "personal family biases" out of the business management of your dairy farming operation.
Ron Hanson is a Neal E. Harlan professor of agribusiness at the University of Nebraska.


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Spruce Up the Sight Word: And
Looking to make sight words more fun? Help your preschooler dress up the word "and," a classic sight word. Assist her by cutting out the cute decorations on the second page of this worksheet, and then allow her to take it from there! The options are as endless as her imagination, and displaying this cute piece of art will give her reading skills a major head start.
For similar worksheets, make sure to check out the rest of our Sight Words printables!


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BP Comment Quick Links
|Strength of Schedule Report
February 12, 2013
Arbitration Showdown
Mock Hearing: Homer Bailey
It's salary arbitration season in Major League Baseball, and here at Baseball Prospectus we're holding mock hearings, arguing for or against the actual team/player filing figures before a three-person panel of certified arbitrators. We've selected 10 of this winter's most intriguing, highest-dollar cases to cover in depth over the first two weeks of February (regardless of whether the players' real-life cases remain unsettled). After each side's opening argument and rebuttal/summation below, we'll give you a chance to vote on what you think the result should be before seeing the panel's decision. For more on the arbitration process, read the series intro by Atlanta Braves Assistant GM John Coppolella, listen to his appearance on Episode 35 of Up and In, or check out the BP Basics introduction to arbitration.
In Part Seven of this 10-part series, we'll tackle Cincinnati Reds pitcher Homer Bailey, who is seeking $5.8 million and has been offered $4.75 million. Bailey and the Reds have yet to reach an agreement. (*Update* Bailey and the Reds avoided arbitration and settled for $5.35 million after this piece was published.)
The complete procedure for salary arbitration is available in the Basic Agreement.
The Case
Homer Bailey was an integral cog in the Big Red Machine of 2012. The 26-year old right-hander took his performance to the next level, helping the Cincinnati Reds to the NL Central crown. For his part, Bailey contributed the best season of his career, as the former first-round pick began to realize his tremendous potential. He has steadily improved his performance throughout his career, building a resume of increasingly stingy run prevention while surrendering fewer baserunners on a per-inning basis. Bailey has also made adjustments to his game that will pay dividends to his future performance for the Reds. His platform performance compares favorably with similar players in his service class, and Mr. Bailey has earned the submitted figure of $5.8 million.
Homer Bailey's History of Performance
Bailey's pattern of improvement was evident within the 2012 season, as he saved his greatest performances for the end of the season. On September 28th, Bailey threw the 15th no-hitter in the 140-year history of the Reds, dominating the Pittsburgh Pirates with 10 strikeouts. A seventh-inning walk to superstar Andrew McCutchen was the only blemish on the near-perfect game. Bailey proved it wasn't a fluke 11 days later, starting Game 3 of the NLDS against the eventual World Champion San Francisco Giants, though he would get the no-decision in a game that went extra innings. Once again, he struck out 10 batters against one walk, pitching seven innings and allowing just a single hit and a lone run in the game.
The improvements in walk rate are the most impressive part of Bailey's statistical development, as what was once his biggest weakness has become a major strength. The average major-league walk rate in 2012 was 3.1 walks per nine innings, and Bailey's walk-rate was 25 percent lower at 2.3 free passes per nine, his second consecutive season of such impressive control.
The progress in Bailey's walk rate is tied to his improved mechanics. The pictures below represent his delivery, at release point, in 2009 as compared to 2012:
2009 2012
Both pictures were taken from the center-field camera feed at Busch Stadium in St. Louis, which allows us to make a direct visual comparison. The yellow line that has been superimposed traces a path that begins with Bailey's front foot and runs vertically at an angle perpendicular to the rubber. In the picture on the left from 2009, Bailey uses a closed stride, in which his front foot is positioned such that it is off-center from the target, and the skewed position had him lined up with the right side of the plate. The result was that he struggled to hit the outside part of the zone.
In the photo from 2012, Bailey's stride is lined up perfectly with the middle of home plate, and he had no problem hitting the outside target for a strikeout. He has also improved his posture over the last few years, as indicated by the position of the head relative to the yellow line. The corrections to Bailey's stride and posture have greatly improved his ability to repeat his delivery and find a consistent release point, which is a very positive indicator for his walk rates in the future.
There is a long list of pitchers within Bailey's 4-year class of service time, allowing us to narrow the range of outcomes to those players who provide the closest comparison to his platform season. The following list comprises every pitcher from the previous three years whose ERA and innings pitched fell within 10 percent of Mr. Bailey's 2012 numbers.
Bailey's numbers adhere very closely to the group averages across the board, and though the exercise was designed to find pitchers with similar ERAs and innings pitched, the other four measures are nearly identical to Bailey's 2012 stats (which were not included in the averages). The group's average salary came in at $5.41 million, which exceeds the midpoint salary of $5.275 million and is close to the $5.8 million figure that we have filed for compensation.
*includes playoffs
Mr. Bailey has established a substantial learning curve throughout his development, and his mechanical improvements support the statistical gains to provide confidence as to his future performance. Bailey was at his best down the stretch, and he stepped up his game under the high-pressure environment of the playoffs. His skills are clearly on the upswing, and he deserves a salary that is commensurate with his peers. —Doug Thorburn
The Reds would like to thank Homer for his contributions as a Red. We are willing to offer him $4.75 million for 2013—a 98 percent increase over what he was paid in 2012.
Unsustainable 2012 Performance
As happy as we are with Homer's production in 2012, we believe it was an outlier. His peripheral statistics from 2012 were essentially the same as his '11 numbers; much of the difference was attributable to factors beyond his control. His batting average on balls in play (BABIP) was abnormally low, at .290. League average is typically around .300, and Homer's career average BABIP, including 2012, is .308. He also stranded baserunners at a higher-than-normal rate in 2012. His left-on-base percentage (LOB%) was slightly above league average (typically around 70 percent) at 73.6 percent. Homer's career average LOB rate, including 2012, is 70.1 percent. Both BABIP and LOB% can vary greatly from year to year and are largely factors of luck; we believe Homer was on the lucky side of both data points in 2012, and expect his ERA, win-loss record, and innings pitched all to regress back to career norms in the coming season.
Innings Pitched
The average salary for these 10 comparable players is slightly over $5.85 million.
The average salary for these 10 comparable players is slightly over $4.6 million.
The average salary for these six comparable players is slightly under $4.46 million.
The injury issues that were mentioned in the Club's opening argument are somewhat misleading. While we acknowledge the risks inherent in pitching, it should be noted that Mr. Bailey's shoulder injury on May 26, 2011, occurred while he was batting, and therefore is not an indication of vulnerability with his pitching motion. The swing-related nature of the incident is particularly relevant with respect to his long-term health, which looks even better when one considers his recent mechanical improvements, and the fact that Bailey has since held a pristine health record is another point in his favor.
The Club has questioned Bailey's ability to sustain his improved performance, stating that he was the beneficiary of fortunate circumstances. However, the evidence available from the pitch-tracking technology of PITCHf/x demonstrates that the right-hander has greatly enhanced the quality of his repertoire, enabling him to become a more effective pitcher. His statistical gains are due to noticeable changes in his approach and his pitch quality, as opposed to the vague explanation of "luck."
In 2009-10, Bailey utilized his fastball greater than 70 percent of the time, allowing opposing hitters to lock in on the pitch. His fastball usage has decreased to 60 percent in 2011-12, and he has integrated his tremendous slider with much greater frequency, upping his slider usage from 11 percent in 2009-10 to over 20 percent in 2011-12. The slider has also gained velocity, with 2012's average speed of 88.0 mph representing the highest mark of his career. The significance of these gains is reflected in the final row of numbers: whiff percentage reflects the frequency of swings-and-misses that are induced by a particular type of pitch, and Bailey's rate of whiffs on sliders has increased by greater than 50 percent between 2009-10 and 2011-12. The pitcher who coaxed just 19 empty swings with his slider in 2009 has upped the ante to more than 100 whiffs in 2012.
The player comparisons that were offered by the Club were each selected based on just a single statistic, with disparate lists based on innings pitched, ERA, and won-loss record. These lists confuse the issue, as there is an ample amount of players for comparison when utilizing the dual constraints of innings and ERA, as demonstrated in the list of 13 pitchers provided in our opening argument. The individual player profiles from our list of comparable pitchers conform much more strongly to the performance of Homer Bailey, and his compensation should reflect the precedent set by his peers. —Doug Thorburn
There is no doubt that Bailey had a stellar 2012, putting up career-best numbers in many categories. But when determining what to offer Bailey for the forthcoming season, we must look at his entire career, not just his fantastic—but luck-aided—2012.
Bailey has pitched four full seasons with the Reds (2009–2012), along with parts of two other seasons (2007–2008). Looking at his career averages in a few key categories over his full seasons brings into relief just how far outside the norm his 2012 lies.
We acknowledge that Homer has become a better pitcher over the course of his career. Mechanical adjustments may have played a role, but we also expect pitchers to improve from year to year as they learn their craft.
In 2012, Homer showed moderate improvement in his hits allowed per nine innings, as well as his home runs, walks, and strikeouts per nine. We also see it with his ERA between 2009 and 2011: a moderate improvement each year. Then in 2012, his ERA dropped nearly by nearly 0.6 runs. If this were due to some dramatic improvement in his mechanics, we would expect to see commensurate improvements across his entire stat line.
But we believe that Homer was simply the beneficiary of better luck in 2012. He allowed fewer earned runs because opposing batters had a relatively low Batting Average on Balls in Play (BABIP), and the baserunners he allowed were left on base at a higher-than-normal rate (as shown in his LOB%). Research has shown that most pitchers have very little control over these factors and the fluctuations in them from year to year are attributable largely to luck.
Ultimately, we are not confident that Homer was able to reinvent himself as an entirely new pitcher in 2012. We know he improved, and we expect him to continue to improve in 2013. But we feel that it is unlikely that he will replicate last season's level of production this year.
One final word regarding Homer's injury history: his representatives are correct in pointing out that there were two separate right shoulder injuries in 2011. One was sustained while hitting, which caused him to miss 27 games. But that was his second 2011 DL stint with a right shoulder injury; he had already missed 30 games earlier that season due to right-shoulder impingement. He also missed 72 games in the previous season (2010) with right shoulder inflammation. While he remained injury-free in 2012, we cannot assume that he will be able to pitch more than 200 innings again this coming season. —Ian Miller
Before scrolling down to read the three-person panel's decision, record your own decision here:
Burt Fendelman is an attorney with more than 45 years of experience, initially in corporate finance and securities laws working as inside counsel for several major securities brokerage firms. He has performed as an arbitrator for FINRA (Financial Industry Regulatory Authority), the American Arbitration Association, and currently as an arbitrator and mediator for the New York County Lawyers Association in fee dispute-related matters. He is presently a self-described "work in progress", working with clients in areas related to art and antiques. He attended Washington University in St. Louis and NYU Graduate School of Tax Law, and he now lives in Manhattan.
Doris Lindbergh is a retired lawyer who is an arbitrator with FINRA (Financial Industry Regulatory Authority) and its predecessor forums, the National Association of Securities Dealers (NASD) and the New York Stock Exchange. She also arbitrates for the National Futures Association (NFA). She attended Washington University School of Law and has a Master of Arts from Fordham University. Her employment history includes stints at Wall Street investment banks and, most recently, the MTA New York City Transit Authority, but her most challenging assignment was raising a future Editor-in-Chief of Baseball Prospectus.
David Marcus is a retired lawyer and serves as an arbitrator with the Financial Advisory Regulatory Authority (FINRA). He lives in Metuchen, New Jersey. He attended Columbia College and Yale Law School, after which he served as an enforcement attorney with the SEC. His subsequent career includes working for the New York Stock Exchange heading its regulatory division, and working for several broker-dealers as a regulatory attorney or General Counsel.
3-0 in favor of the Player
The Sabermetric Perspective/Additional Commentary
Doug made a convincing case that Bailey has improved since his early exposure to the majors, when he was difficult to coach, overly reliant on his fastball, and had trouble putting people away. Ian made a convincing case that the Bailey of 2012, while more durable than he'd ever been before, wasn't noticeably better on a per-inning basis than he had been in recent seasons.* One of the questions the decision came down to was whether Bailey could be expected to be that durable again, since the difference between 118 innings—his three-year average from 2009-11—and 208 innings, his 2012 total, is worth many millions of dollars (provided the quality of the innings is essentially equal). As Ian observed, "While he remained injury-free in 2012, we cannot assume that he will be able to pitch more than 200 innings again this coming season."
*Convincing to a BP audience, at least—Dan Evans, a veteran of over 75 hearings, said that he'd never seen delivery analysis used in an arbitration argument. Not because it couldn't work, necessarily, but because it would present the same risk as attempting to use advanced statistics to sway a panel of people who haven't heard of Bill James or Baseball Prospectus, another tactic teams have historically tended to avoid.
The most depressing part of Ian's assertion is that it actually applies to all pitchers: it's not really safe to assume that anyone will be able to pitch more than 200 innings in a given season. Last December, Matt Klaassen did a study on whether workhorse pitchers can be counted on to continue to work like horses. First he identified instances of three consecutive 200-inning, non-strike seasons over the past two decades. Then he looked at how many innings the pitchers responsible for those durable three-season stretches pitched the following season. He found that their average innings count in year four was only 86.1 percent of what it was from years one through three. In other words, a pitcher who averaged exactly 200 innings per season over a three-year stretch would tend to pitch about 172 innings in the fourth.
And that's the typical drop-off for a starter who's already demonstrated that he deserves to be called durable, the type of pitcher we mentally tend to pencil in for the same number of innings he provided the season before. There aren't many close recent comps for Bailey, a pitcher who made it to the 200-inning mark for the first time after three seasons in the 100-150 range and three shoulder-related stints on the disabled list. One would assume, though, that a pitcher fitting that profile would be a good bet to be in for a bigger decline.
Only five years ago, Bailey was still one of the best 10 prospects in baseball, a consensus future ace. Now, even after what looked like a breakout year, the praise is (understandably) much more measured: Baseball Prospectus 2013 says his upside is "a solid mid-rotation innings-eater." While not the top-of-the-rotation future that was once projected for him, that would still a financially rewarding role, if his appetite for innings is up to it. —Ben Lindbergh
Thanks to Dan Evans, R.J. Anderson, Colin Wyers, Hudson Belinsky, Jonah Birenbaum, and Andrew Koo for research assistance.
Ian Miller is an author of Baseball Prospectus.
7 comments have been left for this article.
BP Comment Quick Links
VERY COOL ARTICLE, everyone! Love this format and reasoning.
Feb 12, 2013 09:25 AM
Is it possible the authors are paying too much attention to the traditional stats?
Feb 12, 2013 09:31 AM
Ben Lindbergh
BP staff
Seemed to me that there were quite a few non-traditional stats (and non-traditional non-stats) cited in this case. I think a team would have to tread very carefully when raising concerns about a player's personality, given that the player is often right there in the room. Telling a panel of arbitrators that a player deserves less money because he's difficult to deal with could very well make matters worse.
Feb 12, 2013 09:44 AM
It seems like the information about his mechanics would be well beyond the understanding of the arbitrators. In previous pieces you note how difficult it is to incorporate advanced metrics into these cases, so something like an analysis of his balance would be well outside the scope of what the arbitrators know how to consider.
Feb 12, 2013 10:29 AM
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SANTA CRUZ -- For Shakespeare Santa Cruz, "The Tempest" has become "All's Well That Ends Well."
The 32-year-old theater company has met its ambitious fundraising goal to continue its mission as an independent theater company, five months after the arts division at UC Santa Cruz announced it would cease operations.
The new company's co-artistic director Mike Ryan said Sunday, "We will have a season in 2014. We don't know where yet, but it will happen."
The company is still in negotiations with UCSC for the use of the Stanley-Sinsheimer Festival Glen, and for the name "Shakespeare Santa Cruz." Operating under the name "Shakespeare Play On," Ryan, co-artistic director Marco Barricelli and members of the Shakespeare Santa Cruz board of directors started a fundraising campaign in early December with the goal of raising $885,000 to revive the company. The campaign, said Ryan, has raised $1.1 million to date.
"That not only allows us to meet our operating costs for 2014," said Ryan, "but it has allowed us to create an endowment to get a head start on 2015."
Ryan said the new season will open on the Fourth of July holiday weekend -- a few weeks earlier than the traditional opening -- and consist of two Shakespeare plays playing in repertory until the middle of August. The plays of the new season, as well as other details of the new season, will be announced in early March.
"Now comes the hard part," said Ryan, referencing the new company's efforts to hire actors and directors for the new season. "We're three months behind, so we're going to have to race to the finish."
Ryan said the donations have come from donors big and small, from foundations and corporations to people from across the country sending in $20 to $25. During the course of its history, Shakespeare Santa Cruz has depended upon its partnership with UCSC to meet its financial obligations. The new model for funding the company, said Ryan, is designed to meet the company's budget before the actors take the stage.
"We're throwing out the credit card and now using the debit card," he said.
Ryan said that the past two months have been a "slog" of writing letters and making phone calls trying to raise the necessary funds to revive what has been Santa Cruz's most prominent theater company for three decades.
"There were some days when I thought it wasn't going to happen," he said. "The thing that we wanted so badly was to know that this community valued what we've done and wanted it to continue to exist. And that's what we got. The outpouring of support has been very generous and we're all grateful."
Follow Sentinel entertainment editor Wallace Baine at Twitter.com/wallacebaine.


text:
8 ounces low-fat cream cheese (room temperature)
3/4 cup of canned pumpkin (unsweetened, unsalted)
3 tablespoons sugar
1/2 teaspoon cinnamon
1/4 teaspoon nutmeg
1/4 teaspoon ground cloves
1/2 teaspoon vanilla
Serve with:
6 apples sliced
Mix all ingredients for the spread together in a mixing bowl by hand or with an electric mixer (medium speed). Serve with apple slices for dipping.
Original article: http://www.mayoclinic.org/healthy-lifestyle/recipes/pumpkin-cream-cheese-dip/rcp-20049947
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text:
What I did last week was, you might say, the cinematic equivalent of what the Scandinavians supposedly love to do -- sit in a sauna until their thighs are boiled hams and their eyeballs are poached eggs, and then go dive naked into a snowbank.
It was like throwing back a big old glass of grain alcohol and chasing it with a quart of baby formula.
Now, there may be 10, or 10 million, movies out there set on the plantation in the antebellum South. But, friends, in one 24-hour period, I saw the bookend extremes of that genre. I'm still recovering from the cultural whiplash.
The first one you've probably guessed by now -- Quentin Tarantino's garish and grotesque "Django Unchained," which astoundingly received the imprimatur of greatness when it got an Oscar nomination for Best Picture last week.
And the second part of my weird double feature? It was Walt Disney's notorious "Song of the South," which, other than theme and setting, had almost nothing in common with "Django." Let's see -- they were both in English, or an approximation thereof... and, well, that's about it.
"Django" is as new as movies get right now and currently in wide release in theaters across the country. It finished second in box office receipts last week to, ahem, "Texas Chainsaw 3-D" (God love America).
By contrast, "Song of the South" is a dusty old cultural artifact from 1946 that is a rarity in this Netflix-ed culture of availability, a movie exiled from public view. It is not now, or has it ever been, available on DVD, other than cheap bootlegs, and was only released on VHS in other countries. It was re-released theatrically in the mid-1980s by Disney, but since then, it's been buried in Disney's vault where it will remain indefinitely.
The reasons why are obvious. Most famous for giving us the song "Zip-A-Dee-Doo-Dah," "Song of the South" is an adaptation of the folk tales of Joel Chandler Harris, known for his "B'rer Rabbit" stories. The Disney film is full of grinning, singing Negroes on some Georgia plantation, including the chortling, kindly old Uncle Remus, the star of the movie. Watching it -- the movie can be seen in its entirety on YouTube, where I saw it -- is like finding the Dead Sea Scrolls of racist African-American stereotypes. These stereotypes are presented not with hostility but with the most overt and gloppy sentimentality you can imagine, which is just as pernicious.
On the other hand, the Tarantino film is a virtual Wagnerian opera of the "n-word," a lurid revenge fantasy featuring actual fountains of bloodshed. Tarantino's title character, played by Jamie Foxx, is as far away from Uncle Remus as Neptune is from Earth. If there is a character that even superficially resembles Remus, it's Samuel L. Jackson as the film's aged and stooped house slave Stephen, and yet the resemblance doesn't go one jot beyond their two balding gray heads. Remus is a bowl full of sugar mush; Stephen is raw meat gone slightly rancid.
I took on this curious experiment to get a sense of how movies carry and reflect cultural values far more effectively than how they portray real history, because if there's anything else that these two movies have in common is that they both have only the barest claim on historical accuracy.
Slavery in the South is, of course, America's original sin and though there are a lot of people -- both white and black -- that would dearly wish we would quit talking about it, obviously, we're still in its thrall. New Year's Day marked the 150th anniversary of the Emancipation Proclamation, and the Oscars this year, despite "Django," is likely to be dominated by a film about Abraham Lincoln, the Great Emancipator.
Hollywood is our great engine of storytelling and though it certainly hasn't ignored the period -- what is widely considered Hollywood's single greatest movie "Gone With the Wind" is a story of the antebellum South -- we have rarely gotten a glimpse of slavery presented on the big screen with much historical fidelity. The closest we've gotten is probably "Roots," in the 1970s, which was, of course, a product of television.
The bookends of "Django Unchained" and "Song of the South" surround a genre with an enormous vacuum in the middle.
They prove that we Americans are very good at talking around a subject to avoid addressing it directly. One of the prevailing clichés of our age is the famous "elephant in the room." When it comes to slavery, we can smell the elephant, hear it, even feel its shadow. But, with notable exceptions like "Roots," we never look at it directly.
I grew up in Atlanta, the hometown of Joel Chandler Harris, the author of the Uncle Remus stories. As schoolchildren, we visited his home, and read the stories of B'rer Rabbit and the Tar Baby. This was right around the time of "Roots," so this odd juxtaposition of two wildly varying stories of Southern slavery has an ancient precedence for me.
But I had never seen "Song of the South" before last week. And, though I may have pulled a muscle or two from wincing at the ridiculous and overcooked stereotypes, I'm glad I saw that particular tip of the elephant's tail.
Now though, it's time to turn and gaze courageously and forthrightly at the beast itself. Is there a filmmaker, preferably an African-American one, out there who can give us the story of slavery as authentically as the artificial medium of movies can deliver? Let's hope so, because the first step is getting the elephant out of your room is to look at it squarely.
Contact Wallace Baine at firstname.lastname@example.com.


text:
phone view phone(703) 744-8000 Address 8484 Westpark Dr Ste 900 #900
Mc Lean, Virginia 22102
United States
Mc Lean, Virginia 22102
United States
|Law School
|American University, Washington College of Law
|Juris Doctorate
|Most recent firm
|BerlikLaw, L.L.C., Reston, VA
|Relevant Jobs
Associate General Counsel
Associate General Counsel The candidate will develop and maintains specific subject expertise and advises businesses management; interacts with relevant third parties as the company's advocate. Has...
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Vice President, Assistant General Counsel, Litigation and Claims The candidate for Claims and Litigation, serves in the capacity of legal expert for matters pertaining to contractual disputes, and fo...
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A. Harrison Barnes is a well-known attorney throughout the United States. As a member of the Malibu community, Harrison is committed to serving the needs of Malibu residents and businesses in legal matters.


text:
On my My Account page, I have a list of things a User can do to his/her Account. I suppose you could call this a menu?!
I am wondering which markup is more semantically correct...

My Account

Upload a Photo

Change My E-mail

Change My Password

Change My Details

My Account

Upload a Photo

Change My E-mail

Change My Password

Change My Details

Definitely go for option 1. It certainly is a list of items, as menus usually are.
So no fears of being accused of "List-itis"?! :lol:
More likely div-itis, depending on whether or not that
 is really needed. But we'd need to see it in context to know.

A series of adjacent links with nothing in between can cause accessibility problems. Using a list helps avoid this. See this article for a brief overview.
Yeah. Definitely go w/ the list.
It's just another menu and is a list/sequence of actions that can be done. Think of it this way.
If I were to say:
You can do these options, what makes more sense, like this:
You can do any of these options:
Upload a PhotoChange My E-mailChange My PasswordChange My Details
or like this:
Fair enough.
According to the very WebAIM page markup, for breadcrumb, which is a list of links, a menu also, you could do this too:
My accountI can: [Upload a Photo | [URL="#"]Change My E-mail | [URL="#"]Change My Password | [URL="#"]Change My Details](#)
where you make
I can:
.hidden {
height: 1px;
left: 0;
overflow: hidden;
position: absolute;
top: -500px;
width: 1px;
Sounds more like it to me. You can choose to hide the '|' also and apply margin or padding related style to links to better visually distinguish among them.
This way, to your visitors, your page won't look like an endless airport strip made from lists.
You mean, since you talk about options, the select element perhaps?
"The select element represents a control for selecting amongst a set of options."
Oh, wait, everyone says lists are what they see there. I say lazy is what they see.
Want something really wild? How about input type="radio". What do I hear? "Meh." I thought so.
I think she's going more for something like Sitepoint's Control Panel (on the left).
Edit: Just saw your quote.
So then why isn't all navigation a select element? It's a choice amongst a set of options... Should lists only be used for paragraph/body content?~TehYoyo
Hmmm ... lazy?!
select was used for menus first. But CSS and JavaScript couldn't do much then, so developers turned on easier paths. The question is, those easier paths developed bad habits?
Lists should be used where they actually fit in the content of a page. They need proper introduction, much like you choose from a "list" of headings before putting down a "list" of paragraphs. Which are "lists" of words. All in a "list" of html markup elements. It's very easy to give up and call "a list" every other couple of things in your sight. How about "set". Or "group". But I guess "list set" and "list group" sounds even better.
It occurred to me that I haven't been so clear about the markup WebAIM uses:

You are here: Home > Articles > Links and Hypertext > Page 3: Hypertext Links

and of my proposal:

My Account

I can: Upload a Photo | Change My E-mail | Change My Password | Change My Details

First, don't use those classes (that specify aesthetics when they should specify content).
I don't get what you're doing...what CSS would you use?
I would give the
 the class "accountOptions" and target the span with p.accountOptions span {}.
The point here is to hide text that sighted users don't need to see.
That's right ralph.
There's nothing wrong with that class name. Also, even though it would work with your descendant selector as well, it appears WebAIM has a lot of content like that one, for accessibility, and as such they used a "hidden" class.
It makes sense to use a class only if there are more accounts to be managed on a page. This is usually not the case, you first log in on a single account and then you manage that one.
TehYoyo, You already quoted the CSS in #10. Pay more attention. Go over to the WebAIM page, first.
Here it is, if you missed it:
With a little bit of help from Firebug, Dragonfly, Developer Tool, Inspector, depending on the UA you use, look for the "breadcrumb" id. It's all there. Even the "hidden" class. That span doesn't have a semantic role, being a span and all, it has a structural and presentational role.
The class is based on how it appears - in best practices of separating structure from appearance, it's best to make classes based on what it is not how it looks.
Yes, everybody seems to know the best practices. Are they? I'm really puzzled by "separating structure from appearance" as a best practice on your part. What that even means? If you wanted to throw something in there, it should have been semantics. Which doesn't apply to span. What would you call a "column" div? A "byte"? A "piece"? A "lot"?
Anyhow, span is a hook for style. The style is hidden. It's not red. Nor green. It's hidden. That's what it is. Maybe you know how hidden looks like?! I've never seen a hidden text before so I guess I can't really describe it to you. If I really think about it, I'm usually not able to describe to you pretty much any hidden object in my sight. LOL
Are you balking at the hidden class? If you are, it could be argued that it defines both what it is and what it looks like. Using it in this situation would be perfectly valid. It's not like he's using a class="columnLeft" or class="colorRed". Hidden objects are just that - hidden. They aren't need for processing or interpretation of pages on a normal basis.
How cynical What I mean is keeping your HTML and CSS separate. That's why we use external stylesheets (one reason), why I (and I think most people) shy away form inline style, etc.
Well then maybe I'm wrong. At first glance, it seems like an appearance class, but looking back on it, it seems more of a comment than anything in the context of the code and of the entire thread.
It isn't an inline style - just a class applied to an inline item. The style is declared elsewhere.
I can see why you think it's an appearance class; as DaveMaxwell says, in one way it is. You could use a class based clearly on what it is: e.g.  but  is much easier to type and means the same thing.
Does that help?


text:
Industry News
Choose Beauty: Vivienne Mackinder
Vivienne Mackinder
Hidden talent: Dressage (guiding a horse through a series of intricate maneuvers).
Day-off pursuits: Spending time in my home with my husband who is an amazing chef. He's the dream husband.
Career other than hairdresser: Prima ballerina, photography, film maker.
Now reading: I'm on a quest for knowledge. I'm reading My One Big Break: Inspiring Stories of Successful Leaders and Business Professionals by John E Grimm III and Clark A. Johnson with Rob Rains.
Title of your autobiography: She Didn't Know How to Stop
In 2009 Vivienne Mackinder was honored with the NAHA Lifetime Achievement Award, and she had already won five NAHAs prior including three years in a row in the Avant- Garde category.
Mackinder and her inventive approach meet the definition of "pre-eminent in the application of new techniques" and she continues to remain in the vanguard of hairdressing.
The Beginning
At 19, aspiring dancer Mackinder hung up her toe shoes and took up scissors. Mackinder trained in her native England at the London College of Fashion learning wig making, sculpting, the fundamentals of classic application and the history of hairdressing.
"We learned the why behind the how," says Mackinder.
Her dream of being onstage did not align with her innate need to innovate. "I found I had no facility for repetition; I liked to do things once."
A friend's advice directed her next move. "Sometimes, people will make a statement that changes your life if you embrace it. A friend said: 'Vivie, darling, if you're going to go out there and work you must work for the best of the best and no compromise.'"
The Mentors
The best were her two mentors: Vidal Sassoon and Trevor Sorbie. "With Sassoon, I learned how to be an architect with my scissors. Trevor taught me how to be a sculptor with my razors and how to dress hair."
She acted as artistic director for both industry icons while honing her skills as a stylist and discovering her facility for educating. She soon found herself directing shows and appearing on platform. "I've spent much more time on the stage than I would have had I stayed a dancer."
Being the Best
Today, Mackinder's base is New York. She is an in-demand session stylist, platform artist, speaker and educator. Mackinder created HairdesignerTV. com, an online educational academy. She also conducts live classes and is unfailingly generous in offering guidance to young stylists.
Mackinder advises: "Visit salons and see if there is anyone doing what you would like to be in five years. Look at their image, the quality of their work and how successful they are."
"It is critical that a salon has an investment in education with accountability. Finally, don't be too impatient to become great."
Sharing the Vision
Mackinder is Fashion Director for Intercoiffure ("It's been an amazing journey"), she consults on education for Simplicity Hair Extensions and has become a certified John C. Maxwell leadership coach.
"As an artist you have to be able to say, what is my next reinvention? I want to help salon owners and managers. It's about building teams. I collaborate and share visions and goals. That is part of being a leader. You can create anything if you can collaborate."
"Every day, I get to celebrate and create beauty—the joy in this has never worn off."


text: I guess many know it, but addiction is addiction. So maybe you like to share how you did overcome it. Don't ask me how. Maybe limited on possibilities which are given after having mastered it so far?DAWN wrote:But, as i see, there is nobody who feel danger in internet and information addiction.


text:
My Inventory of Spare Notebooks
- 08.25.14
- Art Alternatives, Banditapple, Calepino, Doane Paper, Fabio Ricci, Field Notes, Hahnemuhle, HandBook, Journal, Miquelrius, Moleskine, My Collection, Notes & Dabbles, Oxford, Paperblanks, Pen & Ink, Pentalic, Personal, Piccadilly, PSN, Scribe, sketchbook, Zequenz, cahier, drawing, hardcover, notebook, notebook collection, notes, sketchbook, softcover, squared, unlined, writing
- 6 Comments
As you might imagine, I have a lot of notebooks stashed in various places. I have boxes of them under beds and in cabinets and in drawers. They are at home and at the office. They are pretty much everywhere! Lots of them are old ones that I have used. Lots of them are new […]


text:
Translation Disclaimer
Berkeley, California (Tuesday, June 18, 2013) - Berkeley, California (June 18, 2013) – The City of Berkeley Police Department (BPD) will be holding a Driving Under the Influence (DUI) checkpoint, Friday, June 21, 2013.
The checkpoint will be held on Alcatraz Avenue near Adeline in south Berkeley. Participating Officers will begin operations at 8:00 p.m. and staff the checkpoint until approximately 2:00 a.m. Funding for this program was provided by a grant from the California Office of Traffic Safety, through the National Highway Traffic Safety Administration.
Driving impaired is extremely dangerous and the consequences are serious and real. Impaired drivers can kill themselves and others, and the trauma and financial costs of a crash or an arrest for driving while impaired are significant.
During 2010, more than 10,000 people were killed nationwide in a motor vehicle traffic collision involving impaired drivers.
BPD is urging the community to report drunk drivers, call 9-1-1.
Keep up with City of Berkeley news via our News page, email or Follow @CityofBerkeley


text:
Primary Biliary Cirrhosis: Investigating A New Treatment Option Using NI-0801, an Anti-CXCL10 Monoclonal Antibody (PIANO)
This study has been terminated.
NovImmune SA
Information provided by (Responsible Party):
NovImmune SA
ClinicalTrials.gov Identifier:
First received: September 5, 2011
Last updated: April 3, 2014
Last verified: June 2012
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
The purpose of the study is to assess safety and efficacy of multiple doses of NI-0801 in primary biliary cirrhosis patients with an inadequate response to ursodeoxycholic acid.
|Primary Biliary Cirrhosis
|Drug: NI-0801
|Phase 2
|Study Type:
|Official Title:
|An Open Label Single Arm Study to Investigate the Safety and Efficacy of Multiple Administrations of NI-0801, a Fully Human Anti-CXCL10 Monoclonal Antibody in PBC Patients With an Incomplete Response to Ursodeoxycholic Acid
Resource links provided by NLM:
Genetics Home Reference related topics: North American Indian childhood cirrhosis
MedlinePlus related topics: CirrhosisU.S. FDA Resources
Further study details as provided by NovImmune SA:
|Assigned Interventions
|Experimental: NI-0801
|Drug: NI-0801
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Proven primary biliary cirrhosis (PBC), as demonstrated by the presence of at least 2 of the following 3 diagnostic factor (History of increased alkaline phosphatase levels for at least 6 months; positive serum AMA titer; Liver biopsy consistent with PBC)
- Elevated liver enzyme levels at screening
- Have given written informed consent
Exclusion Criteria:
- Screening bilirubin > 2.9 mg/dL (50 μmol/L)
- Screening creatinine clearance < 80 ml/min
- History or presence of hepatic decompensation (e.g., esophageal variceal bleeding, hepatic encephalopathy, or ascites)
- Positive serology result for Human Immunodeficiency Virus (HIV), Hepatitis B or C
- Known or previous diagnosis of malignancy
- Presence of any active infection
- Previous history of active TB within 12 months of screening
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01430429
Please refer to this study by its ClinicalTrials.gov identifier: NCT01430429
|IRCCS Istituto Clinico Humanitas
|Rozzano, Italy, 20089
|United Kingdom
|NIHR Liver Biomedical Research Unit, Queen Elizabeth Hospital
|Birmingham, United Kingdom, B15 2TH
Sponsors and Collaborators
NovImmune SA
More Information
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on September 21, 2017
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
|Responsible Party:
|NovImmune SA
|ClinicalTrials.gov Identifier:
|NCT01430429 History of Changes
|Other Study ID Numbers:
|Study First Received:
|September 5, 2011
|Last Updated:
|April 3, 2014
Additional relevant MeSH terms:
Liver Cirrhosis
Liver Cirrhosis, Biliary
Pathologic Processes
Liver Diseases
Digestive System Diseases
Cholestasis, Intrahepatic
Bile Duct Diseases
Biliary Tract Diseases
Antibodies, Monoclonal
Ursodeoxycholic Acid
Immunologic Factors
Physiological Effects of Drugs
Cholagogues and Choleretics
Gastrointestinal Agents
ClinicalTrials.gov processed this record on September 21, 2017


text:
Why Join AAA? Great Member Services and Benefits!
You know AAA provides the best in emergency roadside assistance. Now check out the other great services and benefits that come with a AAA Membership, like travel planning, car rentals, discounts, insurance and more. If you want additional help on and off the road, AAA Plus is an optional protection plan which, at additional cost, strengthens your Regular Membership.
Nationwide Emergency Road Service
Auto Travel Planning
AAA Travel
Attraction/Hotel/Resort Discounts
AAA Insurance
Financial Services
Show Your Card & Save® Discounts
Fee-Free Travelers Checks
Passport Photos
AAA/Visa® Credit Card
Legal Service Reimbursement
Personal Accident Insurance
Theft Reward
Arrest and Bail Bonds
AAA is an association of regional clubs and your local AAA club is best equipped to provide you with the products or services you need.


text:
COURT proceedings in Winchester came to a grinding halt as barristers walked out in protest at government cuts.
In an unprecedented move, lawyers across the county refused to defend or prosecute cases slated for Monday morning (Jan 6).
Members of the bar are furious at the coalition's attempt to slash the UK's annual £1bn legal bill and say the very future of justice in the UK is at stake.
They launched a last ditch attempt to halt cuts of up to 25 per cent off legal aid fees, which they say will have far reaching consequences.
In a statement read outside Winchester Crown Court, James Newton-Price, a barrister at Pump Court Chambers, spoke on behalf of the Western Circuit, which has around 1,000 members across Hampshire and the South West.
He said: "A lot of damage is being done to your justice system in your name. There is time – just – for the government to pull back from the brink.
"If it does not, it can never now be said that barristers did not warn everyone about what was happening to justice in our society as a direct result of lazy, ill-judged and socially regressive government policy."
He added: "If the rates are not appropriate you can no longer attract the right quality of people and the quality of the profession as a whole is reduced. There will be a greater risk of miscarriages of justice."
Barristers claim that six years' of cuts mean the latest round amounts to a total of 41 per cent in real terms.
They also argue that around 60 per cent of the bar earn £35,000 or less.
Barrister Adam Feest, of 3PB chambers, also took part in the action and said there is a misconception that all barristers earn large sums.
"We feel that we have already made sacrifices over the years and have already taken huge pay cuts and things have now reached a limit," he said.
In September, after fierce opposition from law firms, the government U-turned on proposals to award legal aid contracts to the lowest bidder.
Justice minister Chris Grayling claims the proposed cuts would save £220 million a year.