text: evilzyme 768 Report post Posted April 3, 2013 I was doing my normal morning hockey reads, catching up on the latest news that happened from when I went to sleep until when I woke up, and I came across this article written by Malik. Babcock has said that he loves the new challlenge this young group provides him, and that while decisions and mistakes may make people scratch their head, this is the most consistent group he's had in terms of work ethic and preparation. "It's been exciting and invigorating to coach a team with a lot of kids," Detroit coach Mike Babcock insisted Tuesday in a telephone interview with The Associated Press. "I've heard people say that we're not consistent, but I will say this is the most consistent group we've had in terms of preparation and work ethic since we've been here. Do we make mistakes and do things that make you scratch your head? Yeah, we've got kids playing a lot. But we compete for one and another and that's what we're still hanging in the playoff picture." Along with that, the article provides information on Holland and the trade deadline, DeKeyser and Abby speaking on behalf that any team could win the cup this year. http://kuklaskorner.com/tmr/comments/this-years-red-wings-is-enduring-a-transitional-year-but-its-coach-is-enjoy "Especially in the Western Conference, anybody can beat anybody," Abdelkader said. "You just have to get in the playoffs, when anything can happen. Look at what happened with LA last season" when the Kings became the first eighth-seeded team to hoist the Stanley Cup. "We still have a lot of good pieces here and tremendous leadership and we have a backstop in Howie that bails us out when we need him to," Abdelkader said. "We definitely don't have some of the pieces that have led this team for so many years, but we've got leaders who have stepped up on ice with their play." DeKeyser: "He's coming to a program where things are going to be a bit different, yet we just have to get him in the lineup,'' Babcock said. "The reason we didn't play him this weekend is because he has been off from practice since (Sunday). And we want him to be skating and comfortable for when he does go in for his first game.'' Holland: While Holland believes there will be plenty of trades before the deadline, he doesn't imagine there will be many impact deals done. "I just think it's the league," he said. "I think the conversation we're having today is the same conversation we're having next year and I think it's the conversation from last year. If we pulled up last year's trade-deadline moves, and every year there's between 20-30, 90 percent of them are little depth moves. It's a fourth-round pick for this one, a third-round pick for that one. Every year there's that odd big deal, but teams really make their moves at the June draft. And then there are some rentals. "Obviously, Pittsburgh has been really aggressive, but beyond that I don't think much has gone on around the National Hockey League. I think we wake up Wednesday and because of history we'll have 20-30 trades, but lots of deals will be made for depth. I've had some conversations with some teams about the odd depth player. And I really don't have an interest. Again, because of the development of (Jakub) Kindl, the development of Lashoff, Brendan Smith, because of the signing of Dan DeKeyser on defence, we've got nine guys here and had to trade away Kent Huskins to make room. "Because of the development of Joakim Andersson, who we really like, because Patty Eaves is healthy, because we signed Damien Brunner, who can play in the NHL, you look up front and we don't need any depth. Then you look and Todd Bertuzzi (back injury) is practicing every day and barring any setback we're hoping sometime in the next couple of weeks that he's going to play. It's been tough year for (Darren) Helm for injuries, tough year for Bert with injuries, for Sammy (Mikael Samuelsson) with injuries, but we've been able to stay afloat and I think our depth has kept up afloat. So I can't go out and acquire any better depth than the depth we've got that's kept us afloat." "There are depth players out there that in the past we may have been interested in, but because of what has transpired here over the last 6-8 weeks with all the injuries it's been an opportunity for some young guys to get in and they've done a good job," he said. "Lashoff, Kindl and Andersson have really done a great job. Tatar played well when he was in. I don't think (Gustav) Nyquist has really gotten the opportunity that he really needs. He's sort of in and out. (Tomas) Tatar seemed to have a better opportunity, but there's more people back though. I think we're a deeper team today than we were six weeks ago. And I'm hoping we can get lucky over the next six weeks with some of these injured people. 2 Nev and wingedominance13 reacted to this Share this post Link to post Share on other sites


text:
There is a big kiss in one of the Go Daddy commercials that will debut at the Super Bowl.
No, Danica Patrick doesn't make out with anyone.
Patrick narrates the commercial, which stars model Bar Refaeli and character actor Jesse Heiman. Refaeli is a Sports Illustrated swimsuit issue veteran and a Victoria's Secret angel. Heiman is best known as a … schlub, for want of a better word.
They kiss. Patrick talks and watches.
— MUST-SEE: Best 25 Super Bowl halftime shows
Patrick, who will be a rookie this season in the NASCAR Sprint Cup Series, has starred in Go Daddy's Super Bowl ads since 2007. Her 12 Super Bowl ads is a record for any celebrity.
She apparently had the easy work during this commercial shoot. Refaeli and Heiman did 45 takes of the kiss during filming.
Learn more
— Video: First of two Danica ads | Super Bowl without Danica? | Greatest Super Bowl ads
— Super Bowl XLVII picks: Vinnie Iyer | SN team | Fantasy Source | Linemakers | Troy Aikman

subset: commoncrawl


text:
KINGSTON, N.Y. - A pit bull was shot by city police officers Sunday after the dog was released by its owner to attack when an officer tried to arrest the man, police said.
Police said an officer attempted to arrest David Smith, 32, of 40 Bonnie Brea Lane, Apt. 2, Olive, on an outstanding warrant when Smith was seen walking with the dog at Broadway and Field Court.
Smith allegedly released the dog when the officer approached and the dog then attempted to bite the officer, who radioed for assistance, police said.
Several officers arrived and then attempted to contain the dog and arrest Smith. The officers were able to arrest Smith with the use of a Taser, but the dog attacked the officers, biting one in the hand, police said. Use of a Taser on the dog was unsuccessful and the dog continued to be aggressive, leading officers to shoot the dog, police said.
The dog survived and was taken to an animal hospital for treatment.
The officer who was bitten was treated for injuries to his hand. The officer was not identified.
Smith was charged with felony assault; and three counts of resisting arrest, obstruction of governmental administration, and criminal mischief, all misdemeanors, police said. He was taken to Kingston Police Department for processing prior to expected arraignment in City Court.


text:
The AFC Wildcard Playoff game at 1 p.m. today at M&T Bank Stadium might turn on the moves of Colts coach Chuck Pagano and Ravens coach John Harbaugh, on decisions made or deferred, on challenge flags thrown or held. To punt or not to punt, that is the question.
The truth is there's no way to have a true feel for what Pagano can do as a game-day coach. He's coached four games, three before beating leukemia, one after. He's 2-2. He seems revitalized by his return, the players are thrilled to have him back and offensive coordinator and former interim coach Bruce Arians is the new hot property in the coaching vacancy game.
But we don't know Pagano's on-the-fly decision-making style yet. He hasn't had enough time to reveal it.
If it comes down to a couple coaching moves, the edge has to go to Harbaugh.
Harbaugh has coached nine playoff games, winning five of them. This isn't new territory. Add to that experience the fact Pagano was at Harbaugh's side, as an assistant, picking up tendencies and strategic ideas.
"I would not be standing here today if it wasn't for John Harbaugh and the opportunity he gave me," Pagano said. "He's a fine man, a really good father and an unbelievable football coach with what he's done with the program and that team the last five seasons."
Pagano called Harbaugh a "sounding board" in terms of his coaching growth.
The good news for the Colts is that Pagano has undoubtedly picked up some valuable insight into head coaching from Harbaugh. He might have a hunch about what Harbaugh will do. The bad news is Harbaugh could be pretty good at anticipating Pagano's moves, and use experience to stay a step ahead.
Obviously, the Colts won't be changing an approach they've used all season, with and without Pagano. Arians will still call the plays, using Luck and taking chances. Greg Manusky's defense will again try to limit yards in the red zone, bending a bit but not breaking.
Offensively, the goal is simple: Be as balanced as possible and avoid turnovers. Defensively, stop the run.
But if it's a close game, there's going to be a point where the head coaches make pivotal calls. I thought Pagano should have thrown a challenge flag last week when T.Y. Hilton took Andrew Luck's pass to the goal line and seemed to cross before his knee hit. Pagano didn't challenge, and it was a moot point when Vick Ballard scored afterward.
There are other areas where Pagano's instincts and decision-making have yet to be fully revealed. What will he do in a close game, having the ball just out of field goal range, on fourth-and-short? Points are always at a premium in playoff games.
If Arians lobbies to go for it, will Pagano defer? If Arians hesitates, will Pagano push aggressiveness? Would Luck ever consider waving off the punt team like Peyton Manning? (The first two answers, I don't know. The third answer is: Maybe at some point, but not as a rookie.)
The closer it gets to game time, the more I tend to see the edge leaning toward Baltimore.
Say what you will about Joe Flacco, he's been in the playoffs every season. He's postseason tested. He's not Manning or Tom Brady, but he's been on this playoff stage before. Luck hasn't.
Lewis might be a shell of his former self, but surely he can summon one highly emotional "blast from the past" performance now that he's revealed the end is near.
Then there's Harbaugh. He joined Chuck Knox (Rams) and Bill Cowher (Steelers) as the only coaches since the 1970 merger to lead teams to the playoffs in their first five seasons. Harbaugh has seen everything, experienced everything, and conquered quite a bit, in his five years.
The Ravens were not especially hot entering the playoffs, losing four of their last five. But that one win – a 33-14 blasting of the New York Giants – revealed enough of the old strength to reignite their swagger.
It's tough for any young player to thrive in his first postseason, let alone a team of young players like the Colts. Add a rookie head coach to the mix and that's a lot of playoff newness.
Pagano knows how to deal with stress and adversity. That's a given. But will he go for it on fourth-and-goal in the third quarter of a tied playoff game? We won't know until it happens. Maybe today.
More Information
Colts at BaltimoreKickoff: 1 p.m. today
Radio: WOWO, 1190-AM
For more on the Colts, follow Reggie Hayes via Twitter at www.twitter.com/reggiehayes1


text:
Florida education news: Bullying, turnarounds, bonuses and more
ANTI-BULLYING: The Pasco school district prepares to adopt tougher anti-bullying policies as part of an agreement in the wake of a case at Zephyrhills High School.
TURNAROUND CANDIDATES: See the similarities among five struggling Pinellas schools targeted for big changes.
DUMB: A Brandon-area middle school student is arrested for discharging pepper spray in school, sending dozens to the hospital. • Three Polk middle school students are arrested for plotting to bomb their school, the Ledger reports.
FILM FUN: Some Pasco County schools let students loose to learn by making movies.
NEW OPPORTUNITIES: The leader of Hillsborough Head Start resigns.
ANY ACTION? A bill to overhaul high school sports governance dies in the Florida Senate, Forbes reports. • The Orlando Sentinel summarizes key education bills passed in the session.
OVERHAUL CONTINUES: Manatee's new deputy superintendent of instruction takes over with a clear mission, the Bradenton Herald reports.
MERIT PAY: More than 700 Broward teachers at low-performing schools could be eligible to earn $2,000 bonuses, the Sun-Sentinel reports.
BYOD: Collier schools drop their cell phone ban as teachers aim to incorporate more technology into their lessons, the Naples Daily News reports.
SUSPENDED: A 27-year-old Putnam teacher is suspended for an improper relationship with a 15-year-old female student, the Florida Times-Union reports.
CLEARED: The former Miami-Dade schools police chief is cleared of sexual harassment accusations, the Miami Herald reports.
OUTSOURCING: The Volusia school district hopes to save $30 million over five years by privatizing custodial services, the Daytona Beach News-Journal reports.


text:
Options and Accessories (View All)
Product Summary
Fiber OneShot PRO is your first response, singlemode fiber troubleshooter that locates severe bends, high-loss splices, breaks and dirty connectors in singlemode fiber-up to 15 miles of fiber (more than 23,000 meters) diagnosed in less than five seconds.
General Information
|Product Type
|Cable Analyzer
|Manufacturer Part Number
|Manufacturer Website Address
|Fluke Networks
|Product Model
|Product Name
|Fiber OneShot PRO FIBR-1-KITPRO-VF Cable Analyzer
|Product Line
|Fiber OneShot PRO
|Brand Name
|Fluke Networks
Technical Information
|Length Measurement
|75459 ft
|Test Services
|1 x SC Network
Media & Performance
|Connectivity Media
|Single-mode Fiber
Battery Information
|2 Alkaline AA
|Package Contents
This product is shipped only within Canada and Warranty valid for Canada only.
Computer Valley makes every effort to provide accurate specifications, descriptions, images and price on all products that are found on www.computervalley.ca
However for complete and updated descriptions, compatibilities, specifications and actual photo we recommend our clients to consult with manufacturer's websites or simply call us for proper clarifications. Computer Valley is not responsible and will not accept returns for items purchased that are not compatible with your system. Please ensure that you have verified compatibility and actual photo with your system by visiting the manufacturer's web site prior to purchase or give us a call to make sure what you are purchasing.
For more information, visit our Shipping and Return policy.
Computer Valley wants to provide you with the best and fastest possible service. We try to ship in stock orders placed before 2:00pm EST the same day. For in stock orders placed after 2:00pm EST they are usually shipped the next business day. However there are always exceptions. Please contact us prior to placing your order if you need your purchase by a certain date.
We ship by UPS, FEDEX, USPS, CANADA POST , PUROLATOR and LOOMIS from the nearest locations possible based on stock in hand.
Please note: Computer Valley reserves the rights to accept and cancel any order at anytime due to pricing error or any other reason. An email will be sent as a confirmation of the order status.
|Read Reviews Write Review


text:
Note: This item is more than 11 years old. Please take the publication date into consideration for any date references.
Print – Plain Text – Permalink
News Release
Media Contact: TPWD News, firstname.lastname@example.com, 512-389-8030
Jan. 23, 2006
Brush Control Funding Offered to Landowners
Natural Resources Conservation Service News Release
San Antonio — The Edwards Aquifer Authority and Natural Resources Conservation Service have signed a Memorandum of Understanding to provide financial assistance to enhance range management through brush control on the Edwards Aquifer Recharge Zone.
Brush control, primarily Ashe juniper (cedar) removal, has been identified as a method to increase Edwards Aquifer recharge and improve pastureland productivity.
"The focus of this MOU is to make resources available to help control Ashe juniper, but the opportunity to apply treatment lies in the hands of the private landowners in the Edwards Aquifer Region," said Butler. "With such vast areas of the Edwards Aquifer region affected by the invasive plant, this collaborative effort and shared resources are critical to making dollars stretch farther and maximizing long term success."
By working cooperatively, the Authority and NRCS can help landowners maximize the amount of land they can clear through brush control. In 2006, the Authority has budgeted $300,000 for this program. Under the current NRCS Environmental Quality Incentive Program (EQIP) landowners can be reimbursed for up to 50% of the costs associated with the initial removal of Ashe juniper.
Under the Authority's Range Management Cost Share Incentives Program, landowners can be reimbursed for an additional 20% of their initial Ashe juniper removal costs if they are enrolled in EQIP. Authority funding is also available for up to 50% of follow-up maintenance costs for the Ashe juniper removal.
"This is a great opportunity for the NRCS and the Authority to work together to address a critical natural resource issue in this region," said Potts. "The two programs really compliment one another."
NRCS and Authority reimbursement percentages for initial Ashe juniper removal are based on NRCS-calculated county average costs for the removal method employed. Authority reimbursement for follow-up maintenance costs is based on a per-acre maximum of $15.00.
For more information, call the USDA-NRCS office in your county, listed under "USDA" in the phone book. The information for all NRCS Farm Bill programs is also on the Texas NRCS Web Site. NRCS offers its services free of charge.
On the Net:
Publication — Permission is granted to publish, in whole or in part, any news releases on this page.
Print — A print-friendly version of the news release shows only the release with font sizes set to the browser default.
Plain Text — Plain text versions of TPWD news releases are provided for copying and pasting into editing software.
To copy text into an editing software:
- Click a Plain Text link to display the plain text page in your browser.
- Select all.
- Copy.
- Paste in a document in your editing program.
Permalink — This is a direct link to the news release, omitting the navigation context from the URI.
English/Spanish — News releases posted in both English and Spanish have one of these links.
If you have any suggestions for improving these pages, send an e-mail to email@example.com and mention Plain Text Pages.
(5.4.16 i)


text: G & L Clothing started in 1917 with one mission - to provide durable, quality workwear. We offer specialized styles and sizes, including men's Big and Tall clothing and footwear so you can get down to work. We know it can be a struggle to find everything in one place, which is why we stock it all - pants, shirts, outerwear and underwear. Wherever your workspace - the office, the lab, or the field we carry what you need to get the job done. If you can't find what you're looking for, let us know so we can order it for you! Our team is glad to answer questions about sizing, colors, and fit.


text:
23 Fabulous Picnic Craft Ideas + Restaurant Copycat Recipes
Bonus: Get our newsletter & special offers for free. We will not share or sell your email address. View our Privacy Policy
Latest Comments
"I am going to look for beads at the dollar stores and thrift stores. This will take a lot of beads to make a garland. I think I will use mine on my mantle instead of on my tree. I do have a lot of plastic pony beads already so I might start with those. The colors would look cute by some tiny white Christmas trees."
"What an adorable basket and great way to use up scraps of yarn. I did not even think of a yarn bowl but it would be perfect. I have to do that since I always have my yarn rolling all over the floor. Easy pattern to follow and you can customize it as well. Thank you."
"Wow! All I need to buy is the coconut oil and I am all set. I have plenty of green tea in my pantry. I drink it all the time. I am super sensitive and like to make my own scrubs. This will be perfect. And smell nice as well. Thank you."
"I have a lot of skin sensitivities so I am always looking for something homemade. No reactions there and it works great. This recipe will be do the trick plus smell great. I live in NYC and you need a scrub to take off the impurities of the air. Thank you,"
Spring Mosaic Garden Stone
We are adding the craft to your Craft Projects.
The project was added to your Craft Projects.
Click here to view your Craft Projects.
Get a jump start on spring with this Spring Mosaic Garden Stone from Diamond Tech. Make one or more to add color to your garden. These mosaic stepping stones (patterns included) are sure to bring your garden to life!
- 1 (of each color) 5 oz. package Jennifer's™ Stained Glass Chips in pink, white, light blue, green, light green
- Jennifer's™ Mosaics Outdoor Cement
- 8" Round Stepping Stone Mold
- 1 lb White Grout
- E6000® Glue or Clear Silicone
- Mixing Bowl and Spoon
- Paper Towels and Newspaper
- Wheeled Glass Nippers
- Sponge or Scrubby
- Carbon Paper & Pencil
- Pattern
- To protect work area, cover with newspaper.
- Mix the Outdoor Cement following the directions on the label. Wear a dust mask while mixing.
- Pour cement slowly and evenly into mold; gently tap sides of mold to release any air bubbles in cement.
- Do not move mold while the cement is drying. Wait approximately 24 hours (time may vary due to climate) for cement to harden. The cement will warm as it hardens.
- Once it has cooled and set, remove the stone by turning mold over and lifting up the edges of the mold (MOSAIC SHORTCUT: Use a premade stepping stone from you local hardware or garden center).
- Determine the center of the stepping stone by using a ruler and a pencil. Find the center of the stone. Align the center of the pattern with the center of your stone. Place carbon paper between the pattern and the stone, tape to hold in place. Trace the pattern onto the stepping stone and remove pattern and carbon paper.
- Use the picture as a guide and nip and arrange glass on the entire surface of the stone, leaving approximately 1/8" gap between pieces and at the outer edge. Nip glass pieces with a Wheeled Glass Nipper to fit inside pattern outline.
- Once you have achieved your desired look, lift each piece and apply a thin layer of glue to the back. Firmly press pieces onto the stone. Allow glue to dry according to the manufacturer's instructions.
- To grout the stepping stone, measure 1 cup of grout into a plastic bowl, reserve a few tablespoons of grout and set aside. Adding 1 tablespoon of water at a time to remaining grout, mix with craft stick until the grout reaches "fudge-like" consistency. If it is too watery, add the reserved dry grout in small amounts until the consistency is correct.
- Wearing a disposable glove spread the grout onto the surface of the stepping stone and into all the spaces between the glass and tile. Wait about 15 minutes for grout to set.
- Gently wipe away the excess grout using a paper towel taking care not to pull grout out of tile spaces. It is very important to remove any grout from the tile surface before grout is completely dry.
- Use a soft cloth to buff the tiles to a clean shine.
- Allow 24 hours for the mosaic piece to dry.
Tags / Related Topics
Your Recently Viewed Projects
Images from other crafters
Free projects, giveaways, exclusive partner offers, and more straight to your inbox!
Mar 02, 2016
I used this idea to make a decorative stepping stone as a focal point in a small flower garden where tulips come up in the early spring. The stepping stone adds a bright spot while I'm waiting for those tulips to pop up! Maybe I should add some Crocus, which come up even through the snow! So when I' m tired of winter, I'll have this bright spring-like spot to look at and chase the winter blues away!
Report Inappropriate Comment
Are you sure you would like to report this comment? It will be flagged for our moderators to take action.
Thank you for taking the time to improve the content on our site.
Project of the Day
The Sweatpants Not Just For Sweating
"The fit of the pattern is not the trend of these days which is for thick leggings with pockets. These sweatpants are more in the… See more
Something worth saving?
- SAVE all your favorite crafts
- ADD personal notes
- QUICKLY reference your crafts
Free eBooks
- 11 Crochet Shawl Patterns: Crochet Poncho Patterns, Free Easy Crochet Patterns and More
- 12 Knitted Scarf Patterns: Fabulous Free Knitting Patterns for Beginners
- 14 Free Crochet Patterns for Babies and Toddlers
- 16 Free Crochet Hat Patterns, Scarves, and Gloves
- 22 Free Crochet Patterns: Afghan Patterns, Crochet Hats, and More
- 24 Quick and Easy Knitting Patterns
- 7 Adult Coloring Pages
- 8 Free Apron Sewing Patterns
- Easy Lace Knitting Patterns
- Quick & Easy Decoupage: 12 Fabulous Mod Podge Projects for Your Home


text:
As Pasquarelli writes, One of the stumbling blocks in negotiations between Indianapolis and the top overall choice in the draft ... is the proposed inclusion of marketing language that Luck and his representatives, at least so far, regard as strident. One source with knowledge of the talks even suggested that Luck would have to clear' marketing proposals with the club.
Peyton Manning, also a No. 1 draft pick for the Colts who went on to become a huge poster-boy for a massive amount of different products, apparently didn't have that kind of clause in his rookie contract.
So, if all this is true, it seems unfair for Indianapolis to try to limit Luck's potential to make money on the side, especially with the rookie cap in its second year. At the same time, some in the Colts organization (according to Pasquarelli) believe that Manning was overexposed, which could be why the franchise is trying to exert some control over this matter.


text:
Pharyngitis is a sore throat caused by inflammation of the back of the throat. Your throat may be scratchy and swallowing can be painful. Usually a sore throat is the sign of another illness, such as a cold or the flu. It is one of the most common reasons for visits to family physicians. Unless you have a bacterial infection like strep throat, taking antibiotics doesn't help a sore throat. In fact, most sore throats go away on their own in less than a week.
The symptoms that accompany a sore throat can vary, depending on what's causing it.
Sore throat with flu
Sore throat with mononucleosis
Most sore throats are caused by viruses, although a few are due to bacterial infections. You can breathe in bacteria or a virus from air that has been contaminated when someone sneezes or coughs, or you can transfer the organisms to your mouth or nose by touching a surface with germs on them. Viruses that can cause sore throat include the common cold, the flu, and mononucleosis (often called "mono"). Bacteria like Group A streptococcus, commonly known as strep throat, can also cause pharyngitis. An estimated 30% of childhood pharyngitis is caused by Group A streptococcus.
Risk factors for pharyngitis include:
Your doctor will check your temperature and examine your throat, sinuses, ears, nose, lungs, and neck, including feeling for swollen lymph nodes that may indicate strep throat. He or she may take a throat culture or do a rapid strep test by taking a swab from your throat. A blood test may be done to check for mononucleosis.
If your doctor suspects that you have a sore throat caused by bacteria, such as strep throat, he or she will prescribe an antibiotic. But if your sore throat is caused by a virus, antibiotics won't help. It will go away on its own.
Cool air and humidity may help relieve symptoms. In the meantime, your doctor may recommend gargling with salt water and taking an over-the-counter pain reliever such as acetaminophen (Tylenol) or ibuprofen (Advil, Motrin). Children under 19 should not take aspirin, because of the risk of a rare but serious illness called Reye's syndrome.
If your sore throat is caused by a bacterial infection, your doctor will prescribe an antibiotic. Penicillin or, if you have an allergy to penicillin, erythromycin are most commonly prescribed. In severe cases of group A streptococcus, a single dose of steroids may result in a faster onset of pain relief and reduced suffering.
Because supplements may have side effects or interact with medications, you should take them only under the supervision of a knowledgeable health care provider. Be sure to talk to your physician about any supplements you are taking or considering taking.
There isn't much scientific evidence about which supplements might help treat a sore throat, or reduce your chances of getting a cold of flu. However, a few supplements and nutrients may be worth trying:
The use of herbs is a time-honored approach to strengthening the body and treating disease. Herbs, however, can trigger side effects and can interact with other herbs, supplements, or medications. For these reasons, you should take herbs with care, under the supervision of a health care practitioner. Before giving any herbs to a child to treat a cold, talk to your pediatrician.
To prevent colds and flu:
There are not many scientific studies that have examined which herbs might work to treat sore throat. These herbs have been used traditionally to relieve sore throat pain:
Some people may find relief gargling these teas:
Few studies haved examined the effectiveness of specific homeopathic remedies. Professional homeopaths, however, may recommend one or more of the following treatments for sore throat based on their knowledge and clinical experience. Before prescribing a remedy, homeopaths take into account a person's constitutional type. In homeopathic terms, a person's constitution is his or her physical, emotional, and intellectual makeup. An experienced homeopath assesses all of these factors when determining the most appropriate remedy for a particular individual.
A sore throat usually goes away quickly on its own. If you have had a sore throat for more than a week, or you have a fever, swollen lymph nodes, or a rash, you should call your doctor right away. Fever, swollen lymph nodes, or a rash may indicate strep throat or a complication, such as rheumatic fever. Strep throat requires antibiotics to prevent complications such as:
Alamimi S, Khalil A, Khalaiwi KA, Miner R, Pusic MV, Al Othman MA. Short versus standard duration antibiotic therapy for acute streptococcal pharyngitis in children. Cochrane Database Syst Rev. 2009;1.
Alamimi S, Khalil A, Khalaiwi KA, Miner R, Pusic MV, Al Othman MA. Short-term late-generation antibiotics versus longer term penicillin for acute streptococcus pharyngitis in children. Cochrane Database Sys Rev. 2012;8:CD004872.
Audera C, Patulny RV, Sander BH, Douglas RM. Mega-dose vitamin C in treatment of the common cold: a randomised controlled trial. Med J Aust. 2001;175(7):359-362.
Barrett BP, Brown RL, Locken K, Maberry R, Bobula JA, D'Alessio D. Treatment of the common cold with unrefined Echinacea: a randomized, double-blind, placebo-controlled trial. Ann Intern Med. 2002;137:936-946.
Belongia EA, Berg R, Liu K. A randomized trial of zinc nasal spray for the treatment of upper respiratory illness in adults. Am J Med. 2001;111(2):103-108.
Blakley BW, Magit AE. The role of tonsillectomy in reducing recurrent pharyngitis: a systematic review. Otolaryngol Head Neck Surg. 2009;140(3):291-7.
Brinckmann J, Sigwart H, van Houten Taylor L. Safety and efficacy of a traditional herbal medicine (Throat Coat) in symptomatic temporary relief of pain in patients with acute pharyngitis: a multicenter, prospective, randomized, double-blinded, placebo-controlled study. J Altern Complement Med. 2003 Apr;9(2):285-98.
Choby BA. Diagnosis and treatment of streptococcal pharyngitis. Am Fam Physician. 2009;79(5):383-90.
Douglas RM, Chalker EB, Treacy B. Vitamin C for preventing and treating the common cold. Cochrane Database Syst Rev. 2000;(2):CD000980.
Ferri: Ferri's Clinical Advisor 2010, 1st. ed. Philadelphia, PA: Mosby Elsevier, Inc. 2009.
Hirt M, Nobel Sion, Barron E. Zinc nasal gel for the treatment of common cold symptoms: A double-blind, placebo-controlled trial. ENT J. 2000;79(10):778-780, 782.
Huang Y, Wu T, Zeng L, Li S. Chinese medicinal herbs for sore throat. Cochrane Database Syst Rev. 2012;3;CD004877.
Jackson JL, Lesho E, Peterson C. Zinc and the common cold: a meta-analysis revisited. J Nutr. 2000;130(5S Suppl):1512S-1515S.
Josling P. Preventing the common cold with a garlic supplement: a double blind, placebo-controlled survey. Adv Ther. 2001;18(4):189-193.
Kligler B. Echinacea. Am Fam Physician. 2003;67(1):77-80.
Lindenmuth GF, Lindenmuth EB. The efficacy of echinacea compound herbal tea preparation on the severity and duration of upper respiratory and flu symptoms: a randomized, double-blind placebo-controlled study. J Altern Complement Med. 2000;6(4):327-334.
Long. Principles and Practice of Pediatric Infectious Diseases, 4th ed. Philadelphia, PA: Saunders, An Imprint of Elsevier; 2012.
Mahady GB. Echinacea: recommendations for its use in prophylaxis and treatment of upper respiratory tract infections. Nutr Clin Care. 2001;4(4):199-208.
McElroy BH, Miller SP. Effectiveness of zinc gluconate glycine lozenges against the common cold in school-aged subjects: a retrospective chart review. Am J Ther. 2002;9(6):472-475.
Melchart D, Linde K, Fischer P, Kaesmayr J. Echinacea for preventing and treating the common cold. [Review]. Cochrane Database Syst Rev. 2000;(2):CD000530.
Margolis DJ, Fanelli M, Kupperman E. Association of pharyngitis with oral antibiotic use for the treatment of acne: a cross-sectional and prospective cohort study. Arch Dermatol. 2012; 148(3):326-32.
Mullarkey C. Soothing a sore throat: the efficacy and safety of steroids in acute pharyngitis. Ir J Med Sci. 2011; 180(4):837-40.
Paul IM, Beiler J, McMonagle A, Shaffer ML, Duda L, Berlin CM. Effect of honey, dextromethorphan, and no treatment on nocturnal cough and sleep quality for coughing children and their parents. Arch Pediatr Adolesc Med. 2007;161(12):1140-1146.
Prasad AS, Fitzgerald JT, Bao B, Beck FW, Chandrasekar PH. Duration of symptoms and plasma cytokine levels in patients with the common cold treated with zinc acetate. A randomized, double-blind, placebo-controlled trial. Ann Intern Med. 2000;133(4):245-252.
Roxas M, Jurenka J. Colds and influenza: a review of diagnosis and conventional, botanical, and nutritional considerations. Altern Med Rev. 2007 Mar;12(1):25-48. Review.
Schams SC, Goldman RD. Steroids as adjuvant treatment of sore throat in acute bacterial pharyngitis. Can Fam Physician. 2012; 58(1):52-4.
Shah SA, Sander S, White CM, Rinaldi M, Coleman CI. Evaluation of echinacea for the prevention and treatment of the common cold: a meta-analysis. Lancet Infect Dis. 2007 Jul;7(7):473-80. Review. Erratum in: Lancet Infect Dis. 2007 Sep;7(9):580.
Simasek M, Blandino DA. Treatment of the common cold. Am Fam Physician. 2007 Feb 15;75(4):515-20. Review.
Takkouche B, Regueira-Mendez C, Garcia-Closas R, Figueiras A, Gestal-Otero JJ. Intake of vitamin C and zinc and risk of common cold: a cohort study. Epidemiology. 2002;13(1):38-44.
Turner RB. Ineffectiveness of intranasal zinc gluconate for prevention of experimental rhinovirus colds. Clin Infect Dis. 2001;33(11):1865-1870.
Turner RB, Riker DK, Gangemi JD. Ineffectiveness of Echinacea for prevention of experimental rhinovirus colds. Antimicrob Agents Chemother. 2000;44:1708-1709.
Van Straten M, Josling P. Preventing the common cold with a vitamin C supplement: a double-blind, placebo-controlled survey. Adv Ther. 2002;19(3):151-159.
Vincent M, Celestin N, Hussain A. Pharyngitis. Am Family Phys. 2004;69(6).
Weber R. Bope & Kellerman: Conn's Current Therapy 2013, 1st ed. Philadelphia, PA: Saunders, An Imprint of Elsevier; 2012.
A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org). URAC's accreditation program is an independent audit to verify that A.D.A.M. follows rigorous standards of quality and accountability. A.D.A.M. is among the first to achieve this important distinction for online health information and services. Learn more about A.D.A.M.'s editorial policy, editorial process and privacy policy. A.D.A.M. is also a founding member of Hi-Ethics and subscribes to the principles of the Health on the Net Foundation (www.hon.ch)
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- 2013 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.


text:
7 U.S. Code § 7a–3 - Repealed.
prev | next
Section, act Sept. 21, 1922, ch. 369, § 5d, as added Pub. L. 106–554, § 1(a)(5) [title I, § 114], Dec. 21, 2000, 114 Stat. 2763, 2763A–401, related to exempt boards of trade.
Effective Date of Repeal
Repeal effective on the later of 360 days after July 21, 2010, or, to the extent a provision of subtitle A (§§ 711–754) of title VII of Pub. L. 111–203requires a rulemaking, not less than 60 days after publication of the final rule or regulation implementing such provision of subtitle A, see section 754 ofPub. L. 111–203, set out as an Effective Date of 2010 Amendment note under section 1a of this title.
LII has no control over and does not endorse any external Internet site that contains links to or references LII.


text: Game "looked" good to me.Like Hicks said, it was a thin demo. Couldn't sub, call plays, or even call for a screen. So far I suck, but I assume that has a lot to do with getting used to the controls. Passing seemed a little hard to me anyways. Now for the "Holy ****!" moment. I went to ally oop DWade with Lebron. Which is X+A this year. Well instead of tossing it up to DWade. Lebron tossed it off the backboard, caught it, and threw it down. Animation is smooth. I cant say much for the servers that they so badly need to work on. However i did manage to play 3 games consisting of 1, 5 minute quarter without being booted from the game. So I guess thats a plus, lol.


text:
Monday, February 22, 2010
on my desk monday
6 comments:
- Anna Alter said...
- February 22, 2010 at 12:19 PM
- yamster said...
Beautiful! (And delicious, I'm sure.)
- February 22, 2010 at 2:27 PM
- Carol Hartery said...
Hi Grace!
Do you know the book Hello Cupcake!
If not I am sure you would love it. It has all sorts of amazing cupcake ideas such as dogs, popcorn, a fish bowl, penguins, and more. Carol from The Learning Tree Store
- February 22, 2010 at 3:57 PM
- Katie Davis said...
Wait! Grace! Whose wedding????
- February 22, 2010 at 8:08 PM
- pd said...
Yum, Yum.
I mailed something to your PO, please try to get there by end of week for the surprise.
- February 23, 2010 at 5:03 PM
- Katrina said...
Just a word of warning, my husband and I had a cupcake wedding cake and the kids were all eating it before we were even close to cutting the cake, so I would either bring it out later or put it on a really high table.
- February 27, 2010 at 2:02 AM
Subscribe to: Post Comments (Atom)


text:
By Public Relations |
May 11, 2009
Bethel College will host the fifth annual Luvability in Action Basketball Fundraiser on May 15 at 7 p.m. in Wiekamp Gymnasium. Admission is a $5 donation.
The teams will be featuring Luvability clients as well as: Mishawaka Mayor Jeff Rea; International Motivational Speaker Charlie Adams; Bethel players ─ Ryne Lightfoot and NAIA Player of the Year William Walker; Penn High School's JD Gebbie and Alex Marsh; former Notre Dame basketball players Harold Swanagan and Tom Timmermans; WSBT-TV's Kirk Mason along with local businessmen.
The fundraising game holds two purposes says Luvability Director Linda VanDyke. "It's a basketball game for persons with disabilities to enjoy the sounds, movement and color for the night and to recognize that we all belong to a community."
The second purpose is to raise funds for Luvability Ministries. In 2008, nearly 6,000 people were served through this ministry.
For more information about the fundraiser contact, Bethel Conference Services at 574. 807.7618.
Luvability Ministries is a nonprofit organization that offers Christian opportunities for persons with developmental disabilities and training for those who care for them. It is an effort to communicate the love of God to people with disabilities. This is done mainly through our Worship Arts service where our 16-member team encourages and shares their faith in Jesus Christ with the congregation. For more information about the organization, visit www.luvability.org/.
Bethel College is an accredited Christian college of the arts and sciences offering associate, bachelor's and master's degrees in more than 50 areas of study. The current enrollment of more than 2,000 includes students from 34 states and Puerto Rico, 20 countries, more than 25 denominations and 16 percent from culturally diverse backgrounds. Scholarships are available based upon a variety of factors including academic achievement, talent in the arts or athletics, ethnicity and church affiliation. In addition to its beautifully wooded 75-acre main campus in Mishawaka, Ind., Bethel also offers specific academic programs at sites in Elkhart, Ind., Fort Wayne, Ind., Dowagiac, Mich., and St. Joseph, Mich. Nursing programs are also offered in cooperation with Grace College in Winona Lake, Ind.


text:
Note: This item is more than 11 years old. Please take the publication date into consideration for any date references.
Print – Plain Text – Permalink
News Release
Media Contact: TPWD News, email@example.com, 512-389-8030
Aug. 1, 2006
Hunter's Choice Approved for Waterfowl Season
AUSTIN, Texas — The Hunter's Choice experiment option for the Central Flyway gained approval from the U.S. Fish and Wildlife Service and gives Texas waterfowlers more latitude during the entire season in exchange for a reduction to the daily bag limit from six to five birds.
Believing a bird in the hand is better than two in the bush, Texas Parks and Wildlife Department, along with four other states in the Central Flyway, will have an experimental Hunter's Choice bag limit starting with the 2006–07 season. As part of the Federal Framework adopted last week, the Hunters Choice experiment option will be in effect for the next few years.
With many duck species having maintained or increased their numbers during the last decade, the Service has granted states in the Central Flyway a liberal package framework for determining hunting regulations. But, there have been caveats.
Concerns for select species of ducks have led the Service to take steps to restrict harvest. Those precautionary measures have resulted in complex and confusing regulations, such as "seasons within the season" on some species important to Texas, like pintails.
TPWD officials say the Hunter's Choice alleviates the need for seasons within a season, while providing both protection of certain ducks and season length opportunity for hunters. Five states in the Central Flyway will continue to operate under the 39-day season within a season framework for pintails and canvasbacks
The Hunter's Choice allows hunters to shoot five ducks daily, but only one in the aggregate of certain species. In the aggregate category of less abundant ducks, that one bird could be either a pintail, or a canvasback, or a "dusky duck" (mottled, black duck or Mexican-like duck) or a hen mallard.
"The Central Flyway believes the Hunter's Choice should reduce overall pintail harvest across the flyway," said Dave Morrison, TPWD waterfowl program leader. "In Texas, we believe it will reduce harvest on mottled ducks and address some of the concerns the Service has shown in that species. Had we not gotten Hunter's Choice, we could be looking at other restrictive harvest measures on mottled ducks, but this option gives us time to work with the Service to better understand mottled duck issues."
Although pintails and canvasback populations rebounded somewhat this year, according to the Service's preliminary 2006 Waterfowl Breeding Ground Population and Habitat Survey estimates, they remain below long term goals set in the North American Waterfowl Management Plan. And, while total duck populations improved 14 percent from last year's estimate and remain well above the long term averages, this year's survey also showed drops in scaup and wigeon populations.
The Hunter's Choice will not affect the early teal season in Texas, set for Sept. 9–24 with a daily bag limit of four.
The general duck season length will be the same as last year; 74 days in the North and South Zones and up to 89 days in the High Plains Mallard Management Unit.
How the season structure will unfold is still being discussed, but TPWD has developed a proposal and is seeking public comments prior to presenting recommendations to the Texas Parks and Wildlife Commission for final approval on Aug. 24.
According to federal guidelines, the general duck hunting seasons in Texas can only occur between Sept. 24 and Jan. 28. In making its recommendations, TPWD takes into consideration calendar shifts to maximize weekend and holiday hunting opportunity, and factors in years of survey data on bird migration and hunter harvest. Following is a rundown of the TPWD recommendations being considered:
South Zone — TPWD proposes the following dates: youth-only season Oct. 28–29, regular season Nov. 4–26 and Dec. 9–Jan. 28. This season format will provide a two-week split giving hunters and ducks a rest, while maximizing opportunity during peak historic migrations. It will also provide hunting opportunities until the end of the framework, something many hunters have requested.
North Zone — TPWD proposes a season structure identical to last year, simply adjusted for the calendar shift. Duck season dates would Nov. 4–26 and Dec. 9–Jan. 28, which would give the birds a two-week rest between splits. This format would create an opportunity for a true second split opening day. The youth-only season would run Oct. 28–29.
High Plains Mallard Management Unit — The HPMMU offers one of the longest duck hunting seasons in the nation. To provide a season that takes advantage of this lengthy opportunity, TPWD is recommending season dates of Oct. 21–22 for the youth-only season and Oct. 28–29 and Nov. 3–Jan. 28 for the regular season.
The proposed daily bag limit for all ducks is five and may include no more than two redheads, two scaup, two wood ducks, and one aggregate duck.
As for geese, TPWD is proposing a season similar to last year.
Eastern Goose Zone — White-fronted geese: Nov. 4–Jan. 14; Canada and Light Goose: Nov. 4–Jan. 28.The daily bag limit is three Canada, two white-fronted and 20 light geese.
Western Goose Zone — Nov. 4–Feb. 6 with a daily bag limit of three Canada, one white-fronted and 20 light geese.
The possession limit is twice the daily bag limit for Canada and white-fronted geese and no possession limit for "light geese."
The Light Goose Conservation Order would start at the close of the regular goose seasons and run through March 25 in both zones. This allows relaxed regulations to hunt through various atypical means in order to control light goose overpopulation that has caused damage to Canadian habitat.
Public comment about the waterfowl proposals will be accepted through Aug. 18. Comments should be sent by e-mail to firstname.lastname@example.com or by regular mail to Dave Morrison, TPWD Waterfowl Program Leader, 4200 Smith School Rd., Austin, TX 78744. Input may also be made online via the Public Comment link on the TPWD Web site home page.
Publication — Permission is granted to publish, in whole or in part, any news releases on this page.
Print — A print-friendly version of the news release shows only the release with font sizes set to the browser default.
Plain Text — Plain text versions of TPWD news releases are provided for copying and pasting into editing software.
To copy text into an editing software:
- Click a Plain Text link to display the plain text page in your browser.
- Select all.
- Copy.
- Paste in a document in your editing program.
Permalink — This is a direct link to the news release, omitting the navigation context from the URI.
English/Spanish — News releases posted in both English and Spanish have one of these links.
If you have any suggestions for improving these pages, send an e-mail to firstname.lastname@example.com and mention Plain Text Pages.
(5.4.16 i)


text:
- Home
- News
- Sports
- Opinion
- Obituaries
- Features
- Special Sections
- Classifieds
- Public Notices
LOUISVILLE - It wasn't a flawless performance by the Bullitt East Chargers on Monday in the championship game of the Sixth Region Tournament at Bellarmine University's Knights Hall, but the final 10 minutes were as close to perfection as any high school team is likely to get.
If you currently subscribe or have subscribed in the past to the The Pioneer News, then simply find your account number on your mailing label and enter it below.
Click the question mark below to see where your account ID appears on your mailing label.
If you are new to the award winning The Pioneer News and wish to get a subscription or simply gain access to our online content then please enter your ZIP code below and continue to setup your account.
|ZIP Code:


text:
It's bad enough that the New York Jets know Tim Tebow is now part of the AFC East rival New England Patriots. Unfortunately, ESPNNewYork.com also reports Tebow is still costing the Jets more money than the Patriots spent to add him.
According to the website, the terms of the Jets' 2012 trade with Denver to acquire Tebow for one season has them still paying $1.53 million to the Broncos. That's in stark contrast to the $1.36 million contract — with no guaranteed money over two years — the Patriots used to sign Tebow last week.
There's no guarantee Tebow will make New England's final roster. If he does, you can bet the Patriots will find a way to make him keep lingering in the minds of the Jets on the field. Circle Sept. 12 during NFL Week 2 — that's when the teams face off first in '13 on a Thursday night at Gillette Stadium.


text:
Randomized Study of Tauroursodeoxycholic Acid in Prophylactic Therapy of Total Parenteral Nutrition Associated Cholestasis in Infants
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
OBJECTIVES: I. Determine whether infants treated with tauroursodeoxycholic acid (TUDCA) have a lower peak direct bilirubin, ALT, AST, glutamyltranspeptidase levels and a reduced duration of cholestasis compared to the nontreatment arm.
II. Determine the significance of lower birth weight and longer duration of total parenteral nutrition (TPN) on increasing risk of TPN associated cholestasis and increasing benefit from TUDCA therapy.
III. Determine whether TUDCA therapy leads to significant reduction in the appearance of biliary tract sludge and/or stone formation in these infants.
IV. Determine whether TUDCA therapy leads to reduced urinary excretion of potentially hepatotoxic bile acids as compared to the untreated arm matched for birth weight and duration of TPN.
|Drug: tauroursodeoxycholic acid
|Study Type:
|Study Design:
|Allocation: Randomized
Primary Purpose: Treatment
|Estimated Enrollment:
|Study Start Date:
|June 1998
|Estimated Study Completion Date:
|March 2002
PROTOCOL OUTLINE: This is a randomized study. Patients are stratified by birth weight.
Patients are randomized in pairs by birth weight to receive either a placebo in arm I or tauroursodeoxycholic acid (TUDCA) in arm II. TUDCA is administered by mouth, nasogastric tube, or gastrostomy tube twice daily. After 2 weeks of therapy, a bile sample is obtained via a duodenal tube. An ultrasound examination of the liver and biliary tract is performed after 2 weeks and every 3 weeks thereafter until discontinuation of therapy or until presence of biliary tract sludge is noted on 2 consecutive examinations.
Completion date provided represents the completion date of the grant per OOPD records
|Ages Eligible for Study:
|up to 20 Days (Child)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
--Disease Characteristics--
- Hospitalized infants who are anticipated to require total parenteral nutrition for greater than 2 weeks and have: Major gastrointestinal anomalies (gastroschisis, ruptured omphalocele) OR Resection (necrotizing enterocolitis, volvulus)
- No evidence of biliary tract abnormalities
- No evidence of other forms of cholestatic liver disease
--Patient Characteristics--
- Renal: No life threatening renal disease
- Cardiovascular: No life threatening cardiovascular disease
- Other: No multiple congenital abnormalities
Please refer to this study by its ClinicalTrials.gov identifier: NCT00004410
|United States, Minnesota
|Children's Hospitals and Clinics - Minneapolis
|Minneapolis, Minnesota, United States, 55404
|United States, Mississippi
|University of Mississippi Medical Center
|Jackson, Mississippi, United States, 39216-4505
|United States, Ohio
|Children's Hospital Medical Center - Cincinnati
|Cincinnati, Ohio, United States, 45229-3039
|Study Chair:
|James Heubi
|Children's Hospital Medical Center, Cincinnati
|ClinicalTrials.gov Identifier:
|NCT00004410 History of Changes
|Other Study ID Numbers:
|Study First Received:
|October 18, 1999
|Last Updated:
|March 24, 2015
Keywords provided by FDA Office of Orphan Products Development:
gastrointestinal disorders
rare disease
Additional relevant MeSH terms:
Bile Duct Diseases
Biliary Tract Diseases
Digestive System Diseases
Tauroursodeoxycholic acid
Taurochenodeoxycholic Acid
Antiviral Agents
Anti-Infective Agents
Cholagogues and Choleretics
Gastrointestinal Agents
ClinicalTrials.gov processed this record on September 18, 2017


text:
I enjoy Choral/Orchestral music, and I am seeking any leads to bands/groups that I may not have heard. It is not Operas that I am seeking, but rather Choir pieces that are synthesized into song structures (like Kansas with a Choir). Vangelis, especially his work on the "1492 Conquest of Paradise" album, is certainly one of my favourites. It does not matter if it is Rock (or Metal), Classical, or New Age, as long as the songs (from the recommended bands/groups) are composed utilizing a Choir (and an Orchestra). Sweden's Therion and Norway's Tristania are two examples for which I make mention to, in concept (if you listen to bands as mentioned)
So, that said, any leads to bands/groups that fit the aforementioned desription, would be greatly appreciated (I do not have as of currently, sound on my Comp, so please do not say "check out this download". Also, I do not like (modern day) Metallica, so please make no mention of their S & M album [I have heard parts of it, and it was dross, to me]).
Just trying to find new music to inspire me, as it is rare, and I can not wait for another two years before Therion releases another album (I went out of my way to buy their last release, as it was slated for the US two months after European release. I bought a Korean import of it [got the bonus tracks])
Side note: If anyone enjoys some of the music along the lines that I have mentioned (in concept, if not in actuality), I recommend the soundtrack for "1492..." by Vangelis. It is the most breathtaking album that I have ever heard, especially the last song "Into Eternity".
Therion from Sweden, is my favourite band. If anyone wants to enjoy some modern Classical/Metal music, I recommend that you download the following Therion songs from your site of choice:
1)"The Rise of Sodom and Gomorrah"
2)"The Birth of Venus Illegitima"
3)"From the Dionysian Days"
4)"Ship of Luna"
6)Their version of Orff's "O Fortuna"
7)"Via Nocturna"
8)"Up to Netzach"
10) and if you are more daring, you can check out "To Mega Therion".


text:
WATERFORD, Mich. - The Waterford Fire Department is investigating the cause of a Thursday afternoon house fire.
Fire officials were dispatched to the 3500 block of Mann Road just after noon. When they arrived, they found heavy smoke coming from the front door of the home. Firefighters entered the home and quickly extinguished the fire. They also removed ceiling and interior walls to extinguish hidden flames.
The two residents inside the home were able to escape out a window. Firefighters rescued two cats and gave them oxygen at the scene for serious smoke inhalation.
The fire appears to have started in the kitchen. The cause of the blaze is currently under investigation.
Copyright 2013 by ClickOnDetroit.com. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


text:
FiltersShow / Hide
- All Events
- Rock & Pop
- Acoustic
- Alternative
- Americana
- Indie
- Metal
- Pop
- Punk
- Rock
- Rock & Roll
- Tribute Bands
- Dance & Urban
- Ambient
- Electronic
- Experimental
- Hip-Hop
- Reggae
- Modern RnB
- Ska
- Jazz, Blues & Soul
- Big Band
- Blues
- Classic RnB
- Easy Listening
- Gospel
- Jazz
- Soul
- Swing
- Folk, Roots & World
- Celtic
- Country
- Folk
- Latin
- World
- Classical
- Brass
- Choral
- Classical
- Decades
- 50s
- 60s
- 70s
- 80s
- 90s
- Comedy
- Theatre & Arts
- Shows & Events
- Cinema
- Festivals
- All Tickets
- My Tracked Artists
- Latest Tickets
- Free Events
- Special Tickets
- Disabled Access Venues
- Festival Offers
- Anywhere In The UK
- Location: Anywhere in the UK
Radius: ... miles
Salford's answer to Pavarotti with a debut album 'The Voice' establishing him as a major international tenor. After starting in the pubs and working men's clubs of the north west of England, he's notched up unprecedented chart success on both sides of the Atlantic; has sung for the likes George W Bush and the Pope; and has performed more times at Wembley than Beckham and Owen.
To date, Russell has won four Classical BRIT Awards and has sold over eight million records worldwide. He is also the first artiste to hold simultaneous number ones in the USA and the UK.
See more info at russell-watson.com
4 Russell Watson Tour Dates
Track Russell Watson
- You are tracking Russell Watson
Fans of this artist also track:
- Receive email as soon as new tour dates are announced
- 1,382,365 fans now rely on Ents24 alerts
- Alerts are free and always will be!
- We never share details with 3rd parties
September 2017
Ents24 Widget
PutCustomisable, flexible tour date widget… Super quick set-up, get the code here: tour dates on your web site
Filter By Region
All locations
Want a different location?
News and Announcements RSS feed
No current news or announcements.
Have Your Say
- Read the full review and 15 more
He is most definitely " The People's Tenor " Mitch from Bournemouth
Have you seen Russell Watson? Write a review
Fans who like 'Russell Watson' also like:
Do you represent Russell Watson, or are you a member of their promotional team? Click here to claim this page


text:
The Trinity
Before we begin, I want readers to know I've also made a vlog of this very subject. If you prefer to watch the video, it is down below at the end of this paragraph. If you prefer to read, then feel free to continue reading onward. Regardless, let's talk about the shocking news of Daniel Bryan joining the Wyatt Family on the last RAW of 2013.
I'm not going to lie. I love this new development.
I am making this blog for one reason and one reason alone. That is to bring your attention to a recent trend just started on the WWE's Youtube page. WWE has recently started reaching out to fans to make content on their channel and it's bringing the channel some much needed freshness that's helping it prosper and grow. One of my personal favorite content on the channel is the WWE mashups. It's a collection
Let's clear the air on something. I am a nitpicker. It's a double edge sword. Sometimes I say and do things that I end up regretting much later. But sometimes, I don't. In fact, I'm happy I said it.
We as viewers give these wrestling promotions hours upon hours of our time on a weekly basis. We give pay them thousands upon thousands of our hard earned money each year for PPVs, wrestling
The following blog is a response to a column here on ewrestlingnews. It is titled "WWE's John Cena And Why He Deserves More Respect" which I will summarize quickly with the following quote down below.
A man of great integrity, passion, dedication and a love for the sport he became accustomed to at an early age. His road to WWE and
I have a certain fear right now. I've had this fear for quite some time and it's been a fear I've tried numerous times to ignore. But, no matter how much I try, it keeps gnawing at the back of my skull. So, I felt the need to make this blog in order to do away with this gnawing sensation and express my fear. A fear surrounding a certain wrestler by the name of Daniel Bryan.


text:
Head coach Todd Williams insisted his men are not heading to the MHL Premier Division championship play-offs this weekend to make up the numbers – they are in it to win it.
The Sugden Road side finished the regular campaign in the fourth and final qualifying spot after a 6-5 defeat to Saturday's semi-final opponents East Grinstead last month.
Surbition, who have scored 35 goals in their past seven league encounters, crashed 5-1 to Beeston in last year's final, having beaten Canterbury 5-3 in the semis.
That was the first time the club had reached the final of the showpiece event and Williams reckoned the bitter experience would only help them.
"When we got through the semi-final there was a tremendous out-pouring of relief in the changing room," he said.
"It was a monkey off our backs and I think we were not as focused on the final as we might have been.
"Everyone goes on about qualifying for Europe as the priority, but for me it is about winning the championship. Everything else takes care of itself if we do that."
Surbiton will have the Premier Division's leading marksman Matt Daly in their ranks when they face the league winners on Saturday looking for a place in Sunday's final.
And, while Williams is happy his men will pose an attacking threat, he knows his side must tighten up at the back to prevail.
"Hopefully, we will have learned from the last time we played them," he said.
"We are happy with our scoring potential, but we cannot simply rely on scoring more than them."


text:
Hello fellow MyIGNer's I don't know about you guys but my pre order list is big and getting bigger to my wallet's dismay. I try to ignore the great games that are coming but its hard to ignore when everytime I go to pick one up I am reminded of another. So far this year my list includes: Ni no Kuni: Wrath of the White Witch, Sly Cooper: Thieves In Time, Aliens: Colonial Marines, MLB The Show 13, Soul Sacrifice, South Park: The Stick of Truth, and Grand Theft Auto V. I'm hoping to keep my list at where it is at so wish me luck...
So now I want to know what you are getting this year or are planning to get. And to spice things up a bit. What do you hope gets announced this year? Leave your comments below as always and have a great day. Thanks for reading =D
Good Luck And Godspeed,


text:
Summary: Copenhagen Climate Summit
Click here to download this summary (pdf)
Fifteenth Session of the Conference of the Parties to the
United Nations Framework Convention on Climate Change
Fifth Session of the Meeting of the Parties to the Kyoto Protocol
December 7-18, 2009
Copenhagen, Denmark
A new political accord struck by world leaders at the U.N. Climate Change Conference in Copenhagen provides for explicit emission pledges by all the major economies – including, for the first time, China and other major developing countries – but charts no clear path toward a treaty with binding commitments.
The basic terms of the Copenhagen Accord were brokered directly by President Obama and a handful of key developing country leaders on the final day of the conference, capping two weeks of harsh rhetoric and pitched procedural battles that made the prospect of any agreement highly uncertain. It then took nearly another full day of tense negotiations to arrive at a procedural compromise allowing the leaders' deal to be formalized over the bitter objections of a few governments.
In the end, parties adopted parallel decisions under the U.N. Framework Convention on Climate Change (UNFCCC) and the Kyoto Protocol that "take note" of the political accord and open the way for governments to individually sign on. In separate decisions, parties extended Ad Hoc Working Groups under both the Convention and the Protocol to continue negotiating toward a fuller agreement in late 2010 in Mexico. The unusual set of outcomes leaves uncertainty, however, about the formal standing of the Copenhagen Accord under the U.N. climate process and about the nature of any future agreement. The aim of a "legally binding instrument," which appeared part of the deal when President Obama first announced it, was later stripped out.
Key elements of the Copenhagen Accord include: an aspirational goal of limiting global temperature increase to 2 degrees Celsius; a process for countries to enter their specific mitigation pledges by January 31, 2010; broad terms for the reporting and verification of countries' actions; a collective commitment by developed countries for $30 billion in "new and additional" resources in 2010-2012 to help developing countries reduce emissions, preserve forests, and adapt to climate change; and a goal of mobilizing $100 billion a year in public and private finance by 2020 to address developing county needs. The accord also calls for the establishment of a Copenhagen Green Climate Fund, a High Level Panel to examine ways of meeting the 2020 finance goal, a new Technology Mechanism, and a mechanism to channel incentives for reduced deforestation. (See details below).
The Copenhagen conference culminated two years of intense negotiations launched with the 2007 Bali Action Plan. Known formally as the Fifteenth Session of the Conference of the Parties to the United Nations Framework Convention on Climate Change (COP 15) and the Fifth Session of the Meeting of the Parties to the Kyoto Protocol (CMP 5), the gathering drew a level of political attention well beyond that of any previous climate meeting. Ministers, who ordinarily attend only the final days of the annual COP, arrived the first week hoping to unlock the stalled talks. By its closing days, the summit had drawn well over 100 heads of state and government.
Yet from its opening the conference was marked by bitter divisions, confusion, and setbacks. The Danish government, which had invested extraordinary effort to ensure Copenhagen's success, found itself undermined from the start by the "leak" of a draft text opposed by developing countries. Though President Obama and other leaders had indicated weeks earlier that they foresaw only a political agreement, the talks were bottled up for days by Tuvalu's adamant but unsuccessful demand for immediate consideration of a legally binding outcome. A new draft political agreement finally tabled late in the first week was roundly rejected by developed countries. Attempts to break the impasse by referring core issues to smaller groups of countries, rather than continuing to negotiate all issues with all parties, were repeatedly rebuffed by many developing countries, who insisted on full "transparency" and "inclusiveness."
Those issues continued to dominate in a bitter closing debate as Venezuela, Sudan, Nicaragua, Bolivia and a few others fought to block the leaders' agreement because most parties were outside the room when it was negotiated. Venezuela declared the agreement a "coup d'etat against the United Nations," and Sudan likened its effects on poor nations to those of the Holocaust, prompting a round of angry demands that the comment be withdrawn. Though the accord ultimately won formal recognition despite the lack of full consensus, the episode left many privately questioning the prospects for significant further progress within a fully global, procedurally bound U.N. process.
Other dramas in Copenhagen included open squabbling among the typically unified developing country Group of 77, and the struggle between the issue's two lead protagonists – the United States and China. The two sparred before the press and remained deadlocked behind closed doors until nearly the end. Secretary of State Hillary Clinton, who arrived ahead of President Obama, upped the pressure by declaring U.S. support for the goal of $100 billion a year for developing countries, an offer that many African and small-island countries did not want to let slip by. It was only then that Chinese Vice Foreign Minister He Yafei appeared to concede on U.S. demands that its actions be open to some form of international scrutiny.
President Obama closed the deal the next day in a meeting with Chinese Premier Wen Jiabao, Indian Prime Minister Manmohan Singh, Brazilian President Luiz Inacio Lula, and South African President Jacob Zuma, He then announced the tentative agreement to the press and headed home, leaving other leaders to consider the terms, and weary negotiators to devise the final procedural maneuvers.
Following is a summary of the core outcomes of the Copenhagen conference (full text of all decisions is available at http://unfccc.int/2860.php):
Copenhagen Accord
The Copenhagen Accord is a political (as opposed to legal) agreement of a novel form. Formal decisions under the U.N. climate process are typically taken by consensus. As some parties opposed the accord, the decision entering it into the conference's proceedings is not technically an acceptance of its substantive content by the Conference of the Parties (or by the parallel Meeting of the Parties under Kyoto). Rather, the decisions by the two bodies only "take note" of the attached accord. Individual countries, in all likelihood a strong majority of the Convention's 192 parties, will affix their names to the accord in the coming weeks. The accord declares itself "operational immediately," although many of its provisions will require further elaboration (in some cases explicitly, and in other cases presumably, by the UNFCCC Conference of the Parties). The timeline for doing so is not specified.
In substance, the accord speaks to all of the core elements of the Bali Action Plan: a long-term goal; mitigation; adaptation; finance; technology; forests; and measurement, reporting and verification.
Long-Term Goal – The agreement "recogniz[es] the scientific view that the increase in global temperature should be below 2 degrees Celsius." It also calls for a review of the accord by 2015, including a consideration of strengthening the long-term goal "in relation to temperature rises of 1.5 degrees Celsius."
Mitigation – Under the accord, Annex I (developed) countries "commit to implement" economy-wide emissions targets for 2020, and non-Annex I (developing) countries "will implement mitigation actions." (Least developed and small island countries "may undertake actions voluntarily and on the basis of support.")
The developed country targets and an initial set of developing country actions are to be entered into two appendices by January 31, 2010. It is widely expected, although not specified in the accord, that the targets and actions entered will be consistent with those floated by governments in the run-up to Copenhagen. Additional developing country actions can be added to the appendix on an ongoing basis. Actions for which developing countries are seeking support are to be recorded in a registry, and those receiving support will later be listed in the developing country appendix.
Measurement, Reporting and Verification (MRV) – The emission targets of Annex I countries, and their delivery of finance for developing countries, will be MRV'd "in accordance with existing and any further guidelines" from the COP. These guidelines are to ensure "rigorous, robust and transparent" accounting of both targets and finance.
Actions by developing countries "will be subject to their domestic" MRV, with the results reported in biennial national communications. The information reported will be subject to "international consultation and analysis under clearly defined guidelines that will ensure that national sovereignty is respected." Developing country actions receiving international support will be subject to international MRV under guidelines adopted by the COP.
Adaptation – Developed countries "shall provide adequate, predictable and sustainable" finance, technology and capacity-building to support the implementation of adaptation actions in developing countries.
Forestry – The accord declares the "immediate establishment of a mechanism…to enable the mobilization of financial resources from developed countries" to support efforts to reduce emissions from deforestation and forest degradation and to enhance forest sinks.
Finance – "Scaled up, new and additional, predictable and adequate funding" is to be provided to developing countries to support mitigation efforts (including forest-related), adaptation, technology development and transfer, and capacity-building. For the period 2010-2012, developed countries have a "collective commitment" to provide "new and additional resources…approaching USD 30 billion." Developed countries also commit to a goal of jointly mobilizing $100 billion a year by 2020, "in the context of meaningful mitigation actions and transparency on implementation." The long-term finance is to be a mix of public (bilateral and multilateral) and private resources.
The accord calls for a new Copenhagen Green Climate Fund as one channel for delivering finance and a High Level Panel "to study the contribution of the potential sources of revenue" toward the long-term funding goal.
Technology – The agreement establishes a new Technology Mechanism to accelerate technology development and transfer for both adaptation and mitigation.
Relation to UNFCCC and Kyoto – The accord endorses two parallel decisions under the Convention and the Protocol (see below) extending the two formal negotiating tracks that existed prior to Copenhagen. Those decisions, however, do not cross-reference the accord. Thus, while some parties will likely look to those negotiating processes to elaborate and fully operationalize the accord, no formal link was established.
Ad Hoc Working Group under the Convention
Two years ago in Bali, the COP launched the Ad Hoc Working Group on Long-Term Cooperative Action (AWG-LCA) as the forum for negotiating the "agreed outcome" to be adopted in Copenhagen. A set of decisions addressing the core elements of the Bali Action Plan, and a core decision tying them together, were not completed. While parties made modest progress in some areas, many of the draft texts remain heavily bracketed.
The COP adopted a decision forwarding the texts and extending the mandate of the AWG-LCA "with a view to presenting the outcome of its work…for adoption" next year at COP 16. A draft decision circulated at the time President Obama announced the tentative deal described the intended outcome next year as "a legally binding instrument." However, the phrase did not appear in the text presented at the closing plenary. A number of countries including the United States argued for is reinsertion, but were opposed by others including India and Saudi Arabia.
Ad Hoc Working Group under the Protocol
A parallel Ad Hoc Working Group, the AWG-KP, was established under the Kyoto Protocol in 2005 to consider post-2012 emission targets for developed countries that are party to Kyoto. As with the AWG-LCA, its work remained uncompleted. The Kyoto parties adopted a decision forwarding the incomplete texts and calling on the AWG-KP to complete its work for adoption next year at the meeting of the Kyoto parties to be held in parallel with COP 16.
Dates and Venues of Future Meetings
Parties decided that COP 16/CMP 6 will be held November 29 to December 10, 2010, in Mexico, and that COP 17/CMP 7 will be held November 29 to December 10, 2011, in South Africa.
This summary was written by Elliot Diringer, Vice President for International Strategies, with contributions from International Fellows Kate Cecys and Namrata Patodia, and Daniel Bodansky of the University of Georgia School of Law.
Related Content
Additional Copenhagen/COP15 Resources
Developed Country Submissions to UNFCCC
Developing Country Submissions to UNFCCC


text:
Suns announce Lindsey Hunter will be interim coach
By Ben Golliver
The Suns announced Sunday that player development coordinator Lindsey Hunter has been named interim coach after the team parted ways with Alvin Gentry on Friday.
Hunter, 42 joined the Suns' scouting department in 2012 and was installed in his player development position this season. He spent 17 seasons in the NBA with the Pistons, Bucks, Lakers, Raptors and Bulls, retiring after the 2009-10 season. He was a member of championship teams with the Lakers in 2002 and the Pistons in 2004.
It's unusual for an interim coach to not come from among the full-time assistants. This season, both the Nets (P.J. Carlesimo) and Bucks (Jim Boylan) turned to assistants to step in for their deposed coaches. Yahoo! Sports reported Friday that Elston Turner, an assistant who previously interviewed for a number of head coaching positions, was also a candidate to take over the reins.
So why Hunter? The primary motivations for the Suns in the short term are maintaining motivation and encouraging player development. Phoenix is dead last in the Western Conference at 13-28 and must pursue a multi-year rebuilding plan that will require a roster makeover. Hunter theoretically provides the youth, energy and a former player's perspective to help keep everyone in line and on the track to improvement.
The Arizona Republic reports that Suns GM Lance Blanks said he hoped Hunter would provide the team a much-needed "jolt" while Hunter came out of the gate preaching defense.
"I'm a defensive guy so that's the identity that we're going to try to create, being a tough, nasty, defensive-minded team."
"I love to work. I'm driven by this. I'm kind of obsessed by basketball. I think this is just natural for me."
The Suns currently rank No. 26 in defensive efficiency so there's plenty of work to be done.
For Hunter, this opportunity amounts to a no-risk, all-reward proposition. The only expectation is that his locker room doesn't explode. Past that, Phoenix's rough start hasn't been a surprise and no one can reasonably expect that he will turn it around. If Hunter proves capable of managing the choppy waters, he could be positioned as the coach to lead the rebuilding effort going forward. If not, there's no real harm done either to his coaching career or to the Suns' season.
If Hunter can coax improved play out of core pieces like Goran Dragic and Marcin Gortat, that's all gravy. But his real task will be helping the organization discover what it has in the six players it has with less than three years of experience (Diante Garrett, Wesley Johnson, Kendall Marshall, Markieff Morris, P.J. Tucker and Luke Zeller). The answer is probably "not much," but emergence from any of these guys will be helpful with the roster surely headed into a transition period this summer. It's conceivable that a sell-off could begin even earlier, at next month's trade deadline.
The Point Forward's Rob Mahoney has more on at life after Gentry for the Suns.Picture via Suns.com


text:
Dear Angela,
I've been less active in the church for a couple of years now. I'm not ready — or want — to go back right away, but I was wondering if you could suggest some things I could do as I contemplate the possibility of returning to church. Please keep in mind that I don't want to meet with the missionaries and I don't want the Relief Society president visiting me or anything like that.
Considering Girl
Dear Considering Girl,
There are many simple things that you can do as you contemplate increasing your church activity. I'll give you a list of three and then hopefully those who comment on this article will share some more.
Prayer — All things church-related are designed to bring you closer to Heavenly Father and Jesus Christ. Prayer is one of those things you can do no matter where you are. If you're not ready to attend an actual church service, begin communing with God by simply speaking to him. If praying feels awkward ("Is anyone actually listening?") just say a short one to start. The more you do it, the more natural it will become and the more you'll feel a desire to do other things that will bring you closer to your Heavenly Father.
Listen to the Hymns — Studying the scriptures may not be something you feel like doing — yet. So a great place to start is listening to the hymns of The Church of Jesus Christ of Latter-day Saints. Hymns are scriptures, too, and the same themes that fill the wonderful pages of the Bible and the Book of Mormon can be accessed at LDS.org. Choose a couple to listen to each morning and night. Your mind will feel clear; your heart will feel happy; and you'll begin to enjoy a sweet peace every day.
Choose a commandment — Lifestyle changes don't happen overnight. You can, however, make small adjustments that make you feel good and that propel you in the right direction. Think of a commandment that you can remember (it doesn't matter which one!) and try to live it for one day. Once you've successfully done that, try to live it for a few days, then a week, and so on until it becomes a part of you. The Lord has promised us that when we keep his commandments, he immediately blesses us. If you can get yourself started by choosing one commandment to live, you will be able to experience that very promise for yourself.
Considering Girl, these are just a few things to get you going. Be patient with yourself. Your Father in Heaven loves you and will help you progress if you continue to be open to the promptings that he's already given you. Remember, many people have been less active at one time or another in their lives, but there is always a way back.
Let us know how it goes!
Readers: What additional suggestions could you offer our friend? What blessings have you enjoyed as a result of your church activity?
Share your thoughts in the comment section and like our Facebook page to suggest additional column topics!
Angela Trusty is a young single adult advice columnist for the Deseret News and Washington Times communities. Twitter: @angelatrusty email: email@example.com


text:
A Study of MVA85A, in Asymptomatic Volunteers Infected With TB, HIV or Both
This study has been completed.
University of Oxford
University of Cape Town
Information provided by:
University of Oxford
ClinicalTrials.gov Identifier:
First received: May 30, 2007
Last updated: March 25, 2011
Last verified: March 2011
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Show Detailed Description
This study is designed to evaluate the safety of MVA85A in asymptomatic volunteers in South Africa who are infected with M.tb, HIV or both. A single vaccination with MVA85A, when administered at a dose of 5 x 107pfu intradermally, is safe and highly immunogenic in mycobacterially naïve individuals, BCG vaccinated individuals and M.tb latently infected individuals. We will use the same vaccination regime in this study. Participants will be defined as being infected with M.tb.if they have a positive Elispot response to ESAT6 or CFP10. Participants will be defined as being infected with HIV.if they have a positive HIV rapid test (Determine®, Abbott Laboratories) followed by a positive HIV ELISA result. Participants will be identified from the general population living in Worcester, Western Cape, South Africa
|HIV Infections TB
|Biological: MVA 85A
|Phase 1
|Study Type:
|Study Design:
|Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Prevention
|Official Title:
|A Phase I Study Evaluating the Safety and Immunogenicity of a New TB Vaccine, MVA85A, in Asymptomatic Volunteers Who Are Infected With Either Mycobacterium Tuberculosis (M.tb.), Human Immunodeficiency Virus (HIV) or Both
Resource links provided by NLM:
MedlinePlus related topics: HIV/AIDSU.S. FDA Resources
Further study details as provided by University of Oxford:
Primary Outcome Measures:
- To assess the safety of a single intradermal injection of 5 x 107p.f.u. MVA85A. [ Time Frame: One year ]
Secondary Outcome Measures:
- To assess the effect of a single vaccination with MVA85A in asymptomatic participants who are infected with M.Tb or HIV or both on the immune response, both to antigen 85A (the antigen in the vaccine) and to ESAT6/CFP10 antigens (M.tb specific). [ Time Frame: One year ]
|Estimated Enrollment:
|Study Start Date:
|July 2007
|Study Completion Date:
|January 2011
|Primary Completion Date:
|January 2011 (Final data collection date for primary outcome measure)
|Assigned Interventions
Active Comparator: 1
Group 1: M. tb
Biological: MVA 85A
Modified vaccinia Ankara virus expressing antigen 85A from M. tuberculosis. Dose is 5x10^7
Other Names:
Active Comparator: 2
Group 2: HIV (not on antiretrovirals [ARV])
Biological: MVA 85A
Modified vaccinia Ankara virus expressing antigen 85A from M. tuberculosis. Dose is 5x10^7
Other Names:
Active Comparator: 3
Group 3: M. tb and HIV (not on ARV)
Biological: MVA 85A
Modified vaccinia Ankara virus expressing antigen 85A from M. tuberculosis. Dose is 5x10^7
Other Names:
Active Comparator: 4
Group 4: M. tb and HIV (on ARV)
Biological: MVA 85A
Modified vaccinia Ankara virus expressing antigen 85A from M. tuberculosis. Dose is 5x10^7
Other Names:
Show Detailed Description
|Ages Eligible for Study:
|21 Years to 50 Years (Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
For all groups:
- Asymptomatic adults aged 21 to 50 years
- Chest x-ray normal with no evidence of past/present TB infection or disease or any other clinically significant finding
- Resident in or near Worcester for the duration of the vaccination study
- Willingness to allow the investigators to discuss the volunteer's medical history with the
- volunteer's usual doctor or HIV physician
- Agreement to refrain from blood donation during the course of the study
- Willing and able to provide written informed consent
- Willingness to undergo an HIV test
For the M.Tb infected- and M.Tb/HIV coinfected- groups:
• Screening Elispot positive (more than 50 spots/million PBMC): for either the pool of ESAT6 peptides and/or the pool of CFP10 peptides and screening Elispot positive for PPD.
• Positive Mantoux test. (>10mm induration)
For the HIV infected and M.Tb/HIV coinfected groups:
- HIV antibody positive; diagnosed at least 3 months previously
- CD4 count >300; nadir CD4 not < 300
Exclusion Criteria:
For all groups:
- Any deviation from the normal range in biochemistry or haematology blood tests or in urine analysis that is considered to be clinically significant
- Any previous ARV therapy
- Prior receipt of a recombinant MVA or Fowlpox vaccine
- Use of any investigational or non-registered drug, live vaccine or medical device other than the study vaccine within 30 days preceding dosing of study vaccine, or planned use during the study period
- Administration of chronic (defined as more than 14 days) immunosuppressive drugs or other immune modifying drugs within six months of vaccination. (For corticosteroids, this will mean prednisolone, or equivalent, ≥ 0.5 mg/kg/day. Inhaled and topical steroids are allowed.)
- Pregnant/lactating female and any female who is willing or intends to become pregnant during the study
- Any AIDS defining illness
- History of allergic disease or reactions likely to be exacerbated by any component of the vaccine, e.g. egg products
- Suspected or known current alcohol abuse as defined by an alcohol intake of greater than 42 units every week
- Seropositive for hepatitis B surface antigen (HBsAg) and or hepatitis C (antibodies to HCV)
- Presence of any underlying disease that compromises the diagnosis and evaluation of response to the vaccine (including evidence of cardiovascular disease, history of cancer (except basal cell carcinoma of the skin and cervical carcinoma in situ), history of insulin requiring diabetes mellitus, any ongoing chronic illness requiring ongoing specialist supervision (e.g., gastrointestinal), and chronic or active neurological disease)
- Administration of immunoglobulins and/or any blood products within the three months preceding the planned administration of the vaccine candidate
- Any history of anaphylaxis in reaction to vaccination
- PI assessment of lack of willingness to participate and comply with all requirements of the protocol
- Any other finding which in the opinion of the investigator would significantly increase the risk of having an adverse outcome from participating in this protocol
For the M.Tb infected group (but not the HIV infected and M.Tb/HIV coinfected groups):
- Any confirmed or suspected immunosuppressive or immunodeficient condition, including human immunodeficiency virus (HIV) infection and asplenia
For the HIV infected and M.Tb/HIV coinfected groups (but not the M.Tb infected/HIV uninfected group)
- CD4 count now more than 300 and CD4 nadir not less than 300
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00480558
Please refer to this study by its ClinicalTrials.gov identifier: NCT00480558
|South Africa
|University Cape Town
|Cape Town, South Africa
Sponsors and Collaborators
University of Oxford
University of Cape Town
|Principal Investigator:
|Helen McShane
|University of Oxford
More Information
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Keywords provided by University of Oxford:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on September 25, 2017
McShane H, Pathan AA, Sander CR, Keating SM, Gilbert SC, Huygen K, Fletcher HA, Hill AV. Recombinant modified vaccinia virus Ankara expressing antigen 85A boosts BCG-primed and naturally acquired antimycobacterial immunity in humans. Nat Med. 2004 Nov;10(11):1240-4. Epub 2004 Oct 24. Erratum in: Nat Med. 2004 Dec;10(12):1397.
Goonetilleke NP, McShane H, Hannan CM, Anderson RJ, Brookes RH, Hill AV. Enhanced immunogenicity and protective efficacy against Mycobacterium tuberculosis of bacille Calmette-Guérin vaccine using mucosal administration and boosting with a recombinant modified vaccinia virus Ankara. J Immunol. 2003 Aug 1;171(3):1602-9.
Bejon P, Peshu N, Gilbert SC, Lowe BS, Molyneux CS, Forsdyke J, Lang T, Hill AV, Marsh K. Safety profile of the viral vectors of attenuated fowlpox strain FP9 and modified vaccinia virus Ankara recombinant for either of 2 preerythrocytic malaria antigens, ME-TRAP or the circumsporozoite protein, in children and adults in Kenya. Clin Infect Dis. 2006 Apr 15;42(8):1102-10. Epub 2006 Mar 14.
Huygen K, Content J, Denis O, Montgomery DL, Yawman AM, Deck RR, DeWitt CM, Orme IM, Baldwin S, D'Souza C, Drowart A, Lozes E, Vandenbussche P, Van Vooren JP, Liu MA, Ulmer JB. Immunogenicity and protective efficacy of a tuberculosis DNA vaccine. Nat Med. 1996 Aug;2(8):893-8.
McShane H, Brookes R, Gilbert SC, Hill AV. Enhanced immunogenicity of CD4(+) t-cell responses and protective efficacy of a DNA-modified vaccinia virus Ankara prime-boost vaccination regimen for murine tuberculosis. Infect Immun. 2001 Feb;69(2):681-6.
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Tanner R, Kakalacheva K, Miller E, Pathan AA, Chalk R, Sander CR, Scriba T, Tameris M, Hawkridge T, Mahomed H, Hussey G, Hanekom W, Checkley A, McShane H, Fletcher HA. Serum indoleamine 2,3-dioxygenase activity is associated with reduced immunogenicity following vaccination with MVA85A. BMC Infect Dis. 2014 Dec 3;14:660. doi: 10.1186/s12879-014-0660-7.
Scriba TJ, Tameris M, Smit E, van der Merwe L, Hughes EJ, Kadira B, Mauff K, Moyo S, Brittain N, Lawrie A, Mulenga H, de Kock M, Makhethe L, Janse van Rensburg E, Gelderbloem S, Veldsman A, Hatherill M, Geldenhuys H, Hill AV, Hawkridge A, Hussey GD, Hanekom WA, McShane H, Mahomed H. A phase IIa trial of the new tuberculosis vaccine, MVA85A, in HIV- and/or Mycobacterium tuberculosis-infected adults. Am J Respir Crit Care Med. 2012 Apr 1;185(7):769-78. doi: 10.1164/rccm.201108-1548OC. Epub 2012 Jan 26.
|Responsible Party:
|Dr Helen McShane, University of Oxford
|ClinicalTrials.gov Identifier:
|NCT00480558 History of Changes
|Other Study ID Numbers:
|Study First Received:
|May 30, 2007
|Last Updated:
|March 25, 2011
Keywords provided by University of Oxford:
Human Immunodeficiency Virus
Treatment Naive
Additional relevant MeSH terms:
HIV Infections
Acquired Immunodeficiency Syndrome
Lentivirus Infections
Retroviridae Infections
RNA Virus Infections
Virus Diseases
Sexually Transmitted Diseases, Viral
Sexually Transmitted Diseases
Immunologic Deficiency Syndromes
Immune System Diseases
Slow Virus Diseases
Immunologic Factors
Physiological Effects of Drugs
ClinicalTrials.gov processed this record on September 25, 2017


text:
Wiltshire Police are now recruiting for Police Community Support Officers (PCSOs).
It is the second time in 2014 that the force has recruited PCSOs in order to fill an intake in October. Natural turnover has resulted in PCSO numbers dropping below the minimum requirement.
Applications will be open from today and will allow people to apply at any time within that period. The closing date for applications is Monday 12 May at 5pm. Chief Constable, Pat Geenty, said: "I am delighted that we are in a position to recruit additional Police Community Support Officers. PCSOs provide essential support to police officers and make a real difference to local communities." Police and Crime Commissioner for Wiltshire and Swindon, Angus Macpherson, said: "Police Community Support Officers (PCSOs) are an important part of the police family, being a proactive, visible link between the force and local neighbourhoods alongside their neighbourhood police officer colleagues.
"We are also particularly encouraging applications from minority ethnic communities, as they are presently under-represented within Wiltshire Police." The role Applications are welcomed from both current Wiltshire Police staff and from members of the public. PCSOs provide a visible patrolling presence, acting as an effective crime deterrent, especially with regard to anti-social behaviour. PCSOs do not have the same powers as a police officer therefore duties would not include arrests, investigating serious crimes, carrying out covert operations etc.
To be successful in this role, you must; • Be confident and approachable • Have good communication skills • Have the ability to work on your own, or as part of a team • Possess good problem solving skills • Demonstrate a flexible working approach • Previous experience of dealing with the public and providing a high level of service is essential • Have a good standard of health • Have a full driving licence on appointment. All applications should also be aware that; • There are no minimum or maximum height requirements • There is no formal educational requirement • Only applications from British citizens, EC/EEA nationals, Commonwealth citizens, or foreign nationals with indefinite leave to remain in the UK will be accepted • A number of convictions will mean a definite or likely rejection of your application, including anyone who has received a formal caution in the last five years, committed a violent crime or public order offence • You must be physically and mentally able to undertake police duties • You will need to complete a medical history questionnaire and undergo an eyesight test satisfactorily before your appointment can be confirmed • Some tattoos (whether visible or not) and facial piercings might be unacceptable. For more information, please visit either the Wiltshire Police website www.wiltshire.police.uk


text:
I have a couple star, champ, dx, discs im willing to trade
I am also willing to pay cash.
I'm looking for a 160 to 165 star valk, preferably an orange disc, but weight is more important the color.
If anyone has a star valk in this weight range that there willing to trade/sell please contact me.
Let me know what discs specificly you would trade the star valk for, and/or how much including shiping in cash you would want for the valk.


text:
Dr. David Smith MD Patient Reviews
- Emergency Medicine Birmingham, AL
Overall Rating
2 Patient Reviews
- Friendly Staff
- Promptness
- Wait Time 15 minutes
- Appropriate Followup
- Spends Time With Patients
- Bedside Manner
- Fair and Accurate Diagnosis
- Easy Appointments
Health Guides
Metastatic Melanoma
The facts about metastatic melanoma, a serious skin cancer, including signs, symptoms & what happens to the body in each stage of cancer.
more health guides
Nearby Doctors
Dr. David Smith, MD is similar to these 3 Doctors near Birmingham, AL.
Birmingham, AL
Birmingham, AL
Birmingham, AL


text: The use of energetic nanoparticles offers a promising means of adjusting the reactivity of liquid fuels for enhanced combustion stability in next generation propulsion systems. This work outlines the development of a novel aerosol rapid compression machine (RCM) for studying the impact of energetic nanoparticles on reducing the ignition delay of liquid fuels, and a proof-of-concept demonstration is presented using ethanol and JP-8. Fuel droplets are generated using an ultrasonic nozzle. The seeding of 50 nm aluminum nanoparticles in the liquid fuel is achieved by using a combination of chemical surfactants in addition to mixing in an ultrasonic bath. The autoignition delay is measured for neat and nanoparticle-enhanced mixtures at compressed conditions of 772–830 K and 12–28 bar in the RCM. The results show that significant changes in the ignition delay can be observed using a low concentration (2%-weight) of energetic nanoparticles. For ethanol and JP-8, ignition delays were reduced by 32% and 50%, respectively. Measurements to verify the uniformity of aerosol dispersion in the RCM, the reproducibility of the RCM data, and a method for approximating compressed temperature are also presented.