text:
Oregon State's high-powered passing attack comes to town Saturday, but it's an offense San Diego State's defenders are used to seeing.
The Beavers run a prostyle system similar to the Aztecs.
"They're just like our offense," said Aztecs defensive end Cody Galea. "You see the same plays, the same sets. Everything they do is pretty identical to what we do.
"Everything we've seen in one way or another."
With the spread offense taking hold in college football, prostyle systems are becoming less common. Oregon State is the first prostyle team the Aztecs will face this season, and while the Beavers are tied for the national lead in passing offense (438.7 yards per game), they — like the Aztecs — haven't been able to get a running game going.
For a team still trying to build its confidence after an 0-2 start like SDSU, every little advantage helps.
"We're going to gain (confidence) back by preparing very well and being fundamentally sound in our assignments," said SDSU senior safety Eric Pinkins. "When you're fundamentally sound on your assignments, you're confident.
"This bye week was very helpful for us. We're very optimistic going into this game."
Muema working back to full strength
Lots of eyes will be on running back Adam Muema's left ankle this week.
Muema's low ankle sprain is one reason why the Aztecs have averaged only 93 rushing yards per game this year (compared to 220.7 per game in 2012).
Muema is expected to play Saturday but how effective he will be is anyone's guess.
Muema practiced Sunday for the first time since he reinjured the ankle at Ohio State and Long said he "carried the ball probably 40 times in scout period without any noticeable limp."
At practice on Monday, Long said Muema looked like his old self. He caught a screen pass and ran 20 yards after the catch.
"I think he looks good," senior receiver Colin Lockett said, referring to Muema. "He's getting back to making the cuts he was able to make before, and he's improving every day."
Muema finished 2012 with 1,458 rushing yards but has only managed 22 yards on 13 carries this season because he's struggled with the ankle injury.
Hardwick quits team
Sophomore running back De'Saan Hardwick, a Madison alum, has quit the team, Long confirmed Tuesday.
Long said Hardwick cited a lack of playing time as the reason, and added that he was "a little bit surprised" by the move.
Hardwick was in the mix for the backup running back position, but appeared to have fallen behind Chase Price, D.J. Pumphrey and Dwayne Garrett over the last couple of games. Hardwick got his first career carry against Ohio State -- a 7-yard run.
With three running backs in the same class fighting for backup reps, Long said the Aztecs tried Hardwick at defensive back last fall "but he didn't want to do it."
New offensive line combo
For the third game in a row, the Aztecs will feature a different starting combination on the offensive line.
Darrell Greene has earned the start at right guard, with Terry Poole at right tackle. Zack Dilley will be the primary backup at both positions.
"Darrell played hard and played pretty hard at guard (against Ohio State)," Long said.


text:
Maintenance Treatment of Non Segmental Vitiligo With Tacrolimus Ointment 0.1% Versus Control
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Tacrolimus ointment 0.1% has shown promising results for treating vitiligo in many prospective studies. Prospective randomized studies versus placebo are required to confirm the hypothesis that maintenance treatment with two applications of tacrolimus ointment 0.1% per week can reduce relapses of non-segmental vitiligo lesions.
Main objective To assess the efficacy of maintenance therapy with topical tacrolimus vs placebo in the prevention of depigmentation in patients with vitiligo who responded to treatment.
Secondary objectives
- Evaluate the efficacy of maintenance therapy with tacrolimus vs topical placebo to decrease the intensity of depigmentation in patients with vitiligo who responded to treatment.
- To study the occurrence of possible adverse effects.
Length of the study Inclusion: 12 months Treatment: 6 months Follow-up: 6 months Total length of the study: 18 months
Intervention Multicentric prospective interventional randomized comparative study versus placebo.
- Visit V0: Selection Information of the patient, control of inclusion and non inclusion criteria.
- Visit V1: Control of inclusion and non inclusion criteria, patients signed informed consent. An initial clinical evaluation and photographs in direct sunlight and UV. Topical treatment (tacrolimus or placebo) will be delivered to the patient by the hospital pharmacy and should be applied twice per week (3 or 4 days apart) for 24 weeks.
- Visit V2:
The patient will be reviewed after the end of treatment (24 weeks after the visit V1) for final evaluation. A clinical assessment will be made and photographs in the same way as the inclusion. Adverse reactions during treatment will be collected by the investigator (they will be noted as and when the patient in a notebook that will be presented at baseline).
The percentage of depigmentation will be evaluated in a blinded treatment of photographs by two reviewers. In case of disagreement, the opinion of a third appraiser will be required.
- End of study: After the end of the study patients will be supported via the usual care recommended for their condition.
Evaluation criteria
primary endpoint
---Percentage of patients at 24 weeks without depigmentation (depigmentation score = 0). A score of depigmentation from 0 to 2 will be used. A blind treatment evaluation of direct light and UV photographs will be made by two independent observers (dermatologists) between inclusion and after 24 weeks of treatment.
secondary endpoints
---- The efficiency to reduce the intensity of relapses will be evaluated using the score of depigmentation (rate of patients with a score of 0 or 1 in each group) and the VASI score (Appendix 4).
- The frequency, severity and time of occurrence of adverse events are reported. Side effects are classified into grades according to WHO criteria.
Number of subject Considering that depigmentation occurs in more than 40% of patients during the 24 weeks of maintenance treatment and hoped that the proactive treatment will reduce the rate of depigmentation of 10%, a population of 26 patients per group will be necessary (taking into account 10% of patients lost to follow). The total number of patients to be included in the study will be 52.
|Pigmentation Disorders Vitiligo
|Drug: Protopic Drug: Placebo : Diprobase
|Phase 2 Phase 3
|Study Type:
|Study Design:
|Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Participant, Investigator)
Primary Purpose: Treatment
|Official Title:
|Maintenance Treatment of Non Segmental Vitiligo With Tacrolimus Ointment 0.1% Versus Control, Randomized and Double Blind Study
- UV and direct light photographs [ Time Frame: At 6 months ]Comparison of photographs between day 0 and 24 weeks by two independent-blinded dermatologists
- Score of depigmentation, VASI score. Frequency and severity of adverse events. [ Time Frame: At 6 months ]Score of depigmentation, VASI score. Frequency and severity of adverse events.
|Study Start Date:
|December 2011
|Study Completion Date:
|June 2014
|Primary Completion Date:
|June 2013 (Final data collection date for primary outcome measure)
|Assigned Interventions
|Experimental: Tacrolimus ointment 0.1%
Drug: Protopic
Topical treatment (tacrolimus or placebo) will be delivered to the patient by the hospital pharmacy and should be applied twice per week (3 or 4 days apart) for 24 weeks.
|Placebo Comparator: Group Placebo
Drug: Placebo : Diprobase
Topical treatment (tacrolimus or placebo) will be delivered to the patient by the hospital pharmacy and should be applied twice per week (3 or 4 days apart) for 24 weeks.
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Age > 18 years
- Non-segmental vitiligo repigmented more than 75% with treatment (any type of treatment is accepted: NB-UVB, PUVA, lamp or excimer laser at 308 nm, topical steroids, topical tacrolimus, graft). The total area treated plates during maintenance treatment should not exceed 10% of the total body surface area.
- Affiliation to the Social Security
- Informed consent signed by the patient
Exclusion Criteria:
- Segmental Vitiligo
- Pregnant or breastfeeding women (pregnancy test will be conducted); effective contraception will be maintained for the duration of the study.
- Allergy to macrolide derivatives.
- Exposure to UV or concomitant exposure to the sun without protective shield.
- Concomitant immunosuppressive therapy or oral corticosteroids for topical (on the vitiligo lesions) or systemic
Please refer to this study by its ClinicalTrials.gov identifier: NCT01841008
|CHU de Nice - Hôpital de l'Archet
|Nice, Alpes-Maritimes, France, 06200
|CHU de Bordeaux
|Bordeaux, Gironde, France, 33 404
|Principal Investigator:
|PASSERON Thierry, Pu-Ph
|CHU de Nice - Service de Dermatologie - Hôpital de l'Archet - 151 Route de saint-antoine de ginestière 06200 Nice
|Responsible Party:
|Centre Hospitalier Universitaire de Nice
|ClinicalTrials.gov Identifier:
|NCT01841008 History of Changes
|Other Study ID Numbers:
|Study First Received:
|March 23, 2012
|Last Updated:
|September 4, 2014
Keywords provided by Centre Hospitalier Universitaire de Nice:
Additional relevant MeSH terms:
Pigmentation Disorders
Skin Diseases
Immunosuppressive Agents
Immunologic Factors
Physiological Effects of Drugs
Calcineurin Inhibitors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
ClinicalTrials.gov processed this record on September 25, 2017

subset: commoncrawl


text:
'); var yuipath = 'clientscript/yui'; var yuicombopath = ''; var remoteyui = false; } else // Load Rest of YUI remotely (where possible) { var yuipath = 'http://yui.yahooapis.com/2.9.0/build'; var yuicombopath = 'http://yui.yahooapis.com/combo'; var remoteyui = true; if (!yuicombopath) { document.write('
Actually, he is becoming his father. The only time this moved forward was when Jim hired Polian and got out of the way. I think he is being involved now and that is a recipe for disaster. I am not "dude" either...... ...
Well once again, I disagree.
There are two types of quarterbacks in the league: Those whom over time, the league figures out ... and those who figure out the league.
The real question is if the rookie TE's can match Clarks numbers but lets be honest that shouldn't be too hard considering his numbers the past two years.
Really think you'll be able to talk sense into him? he is probably still arguing that the world is flat and it's Irsay's fault.
Oh man, Blu, are you setting yourself up for one helluva crow-eating contest this winter.
There are two types of quarterbacks in the league: Those whom over time, the league figures out ... and those who figure out the league.
I doubt it. That means I am in there 0-4 wins and I doubt that they win four. I think many people are going to be surprised by how bad they really will be. As far as Luck in concerned, I remember when Jeff George came in with the same "can't miss" hype. He turned out to be a better than average QB for a number of teams for a number of years and he didn't join the Colts in full rebuild mode.... Peyton also joined a MUCH better Colts team than the one Luck come to.....
And I hope you are right but I strongly doubt that you are.....
What helped Peyton's Colts tremendously was the fact that we got Edge the season after Manning's rookie year. He was an instant stud. See, a lot of the players who will help Luck over his career aren't even on the roster right now. If we don't win a lot of games then that at least means we will have a high draft pick. Plus we have a ton of cap space next season.
Who did the Colts have on defense Manning's first year?
In Manning's rookie season, there were just *two* players on the roster who would wind up being extremely important foundational pieces, Harrison and Glenn.
revisionist history is grand. all it comes down to is he doesn't like Irsay getting rid of Manning and the boys so he's going to spin everything like the Colts are doomed and every decision is a bad one. If Colts picked RG3, then he'd probably be singing praises about how great Luck is and how we should have picked him.


text:
Cron, Lindsey among five prospects cut from camp
TEMPE, Ariz. -- The Angels cut left-handed reliever Robert Carson, first baseman C.J. Cron, catcher Anderson De La Rosa, second baseman Taylor Lindsey and utility man Shawn O'Malley from Major League camp on Thursday, whittling their Spring Training roster to 49 players.
Cron, ranked second among Angels prospects by MLB.com last season, had a solid spring, batting .400 (6-for-15) with a home run and showing improvements defensively, and could come up later in the season to serve as a right-handed platoon at designated hitter.
Lindsey, ranked third, went 1-for-9 in limited time and is expected to start the season at Triple-A Salt Lake, where he'll team with Cron and work specifically on polishing his defense.
De La Rosa never arrived to camp because of visa issues in his native Venezuela.
Alden Gonzalez is a reporter for MLB.com. Read his columns and his blog, Gonzo and "The Show", and follow him on Twitter @Alden_Gonzalez. This story was not subject to the approval of Major League Baseball or its clubs.


text:
Note : Your Quotation Request will be directed to Mini Circuits.
The ZX95-2085 from Mini Circuits is a Voltage Controlled Oscillator with Frequency 2095 to 2115 MHz, Power 4 dBm, Supply Voltage 5 V, Supply Current 35 mA, Phase Noise -81 dBc/Hz. More details for ZX95-2085 can be seen below.
173 to 192 MHz, Surface Mount Voltage Controlled Oscillator
You can now find similar products from multiple companies on everything RF.


text:
Get an overview of this hotelEco-friendly hotel with 6 restaurants and full-service spa
Popular property highlights
Located in the heart of Windsor, this spa hotel is 0.6 mi (1 km) from Detroit Windsor Tunnel and within 3 mi (5 km) of Ambassador Bridge and University of Windsor. GM Renaissance Center and Ford Field are also within 6 mi (10 km).
Hotel Features
6 restaurants, a full-service spa, and a casino are available at this hotel. Free WiFi in public areas and free valet parking are also provided. Additionally, an indoor pool, 2 bars/lounges, and a health club are onsite.
Room Amenities
All 758 rooms offer free WiFi and free wired Internet, flat-screen TVs with cable channels, and comforts like pillowtop beds and premium bedding. Guests will also find sitting areas, refrigerators, and minibars.
Guest Highlights
- Comfortable rooms
- Good location
- Helpful staff
- Clean, quiet guestrooms
- Guestroom size
- Room service could've been better
Caesars Windsor
Hotel Amenities
Hotel Amenities
In addition to a full-service spa, Caesars Windsor features an indoor pool and a health club. Dining is available at one of the hotel's 6 restaurants and guests can grab coffee at the coffee shop/café. Guests can unwind with a drink at one of hotel's 2 bars/lounges. Wired and wireless Internet access is complimentary.
Business amenities at this 4-star property consist of a business center, limo/town car service, and meeting rooms. This eco-friendly hotel also offers a casino, a spa tub, and a sauna. Onsite self parking and valet parking are complimentary.
Caesars Windsor has designated areas for smoking.
- 24-hour front desk
- Total number of rooms - 758
- Number of floors - 26
- ATM/banking
- Number of bars/lounges - 2
- Breakfast available (surcharge)
- Business center
- Casino
- Coffee/tea in common areas
- Coffee shop or café
- Free newspapers in lobby
- Conference space
- Dry cleaning/laundry service
- Elevator/lift
- Express check-out
- Full-service spa
- Gift shops or newsstand
- Health club
- Designated smoking areas
- Free WiFi
- Free wired Internet
- Limo or Town Car service available
- Meeting rooms 13
- Free valet parking
- Porter/bellhop
- Safe-deposit box at front desk
- Number of restaurants - 6
- Conference center
- Free self parking
- Sauna
- Number of buildings/towers - 2
- Spa services on site
- Spa tub
- Indoor pool
Available in all rooms: Free WiFi , Free wired Internet
Available in some public areas: Free WiFi , Free wired Internet
Free self parking, Free valet parking
Room Amenities
- Premium TV channels
- Pay movies
- Premium bedding
- Separate sitting area
- Air conditioning
- Free newspaper
- In-room climate control (air conditioning)
- Phone
- Refrigerator
- Minibar
- Coffee/tea maker
- Daily housekeeping
- Private bathroom
- Designer toiletries
- Hair dryer
- Separate bathtub and shower
- Pillowtop mattress
- Flat-panel TV
- Iron/ironing board
- In-room safe
- Desk
- Rollaway/extra beds available
- Cribs/infant beds available
- Blackout drapes/curtains
- Cable TV service
- Free WiFi
- Free wired Internet
- Room service
- Connecting/adjoining rooms available
Where to Eat
Market Buffet - This buffet restaurant serves brunch, lunch, and dinner. Guests can enjoy drinks at the bar.
Neros Steakhouse - This steakhouse serves dinner only. Guests can enjoy drinks at the bar. Reservations are required. Open daily.
Legends Sports Bar - This pub serves dinner only. Guests can enjoy drinks at the bar.
Artist Cafe - This café serves breakfast, brunch, lunch, and dinner. Guests can enjoy drinks at the bar.
Pronto Cafe - This café serves lunch and dinner.
Room service is available.
Nearby Things to Do
An indoor pool and a spa tub are on site. Other recreational amenities include a health club and a sauna.
Guests under 19 years old are not allowed in the swimming pool, health club, fitness facility, or spa tub.
The recreational activities listed below are available either on site or nearby; fees may apply.
- Golfing nearby
- Golf lessons available nearby
Spa Services
Guests can indulge in a pampering treatment at the hotel's full-service spa, The Spa by Windsor Arms. Services include deep-tissue massages, hot stone massages, massages, and facials. A variety of treatment therapies are provided, including aromatherapy and reflexology. The spa is equipped with a sauna.
The spa is open select days. Guests under 19 years old are not allowed in the spa.
- Hot stone massage
- Deep tissue massage
- Prenatal massage
- Reflexology
- Manicures and pedicures
- Body wraps
- Body scrubs
- Aromatherapy treatments
- Sauna in spa
- Massages
- Minimum age to access spa is 19
- Body treatments
- Facial treatments
If you have requests for specific accessibility needs, please note them at check-out when you book your room.
- Accessible bathroom
- Roll-in shower
- In-room accessibility
Hotel Policies
Check-in time starts at 4 PM
Minimum check-in age is 19
Check-out time is 11 AM
Payment types
Children and extra beds
- Children are welcome.
- Rollaway/extra beds are available.
- Cribs (infant beds) are available.
- Pets not allowed
You need to know
Extra-person charges may apply and vary depending on property policy.
- The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation.
- Deposit: CAD 200.00 per stay
- Resort fee: CAD 11.30 per accommodation, per night
Optional extras
- Breakfast fee: between CAD 10 and CAD 15 per person (approximately)
Hotel Name
- Caesars
- Caesars Hotel
- Caesars Hotel Windsor
- Caesars Windsor
- Windsor Caesars
- Caesars Windsor Hotel Windsor
- Caesars Windsor Ontario
- Casino Windsor Hotel
- Windsor Caesars Hotel
- Windsor Casino
We should mention
Reservations are required for massage services and spa treatments. Reservations can be made by contacting the hotel prior to arrival, using the contact information on the booking confirmation. The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation. Some facilities may have restricted access. Guests can contact the property for details using the contact information on the booking confirmation.


text:
This product is out of stock and might not be available again.
contact us for more info.
The Niner RDO stem is trimmed down to race-ready essentials and made to match and complement your Niner bike. Light and stiff, with a tested and true 4-Bolt faceplate and stainless black hardware, the RDO stem is exactly what the modern race bike needs and nothing more. Available in a glossy black finish, with four RDO colors to match Niner's bikes and components.
Material: Aluminum
Rise: +/- 6 degrees
Clamp: 31.8mm
Length: 80, 90, 100, 110mm
Steerer: 1 1/8"
Weight: 115 g.


text:
I decided to write this column before the Mountain Fire mandatory evacuation was lifted.
Needless to mention, starting Monday, July 15, the residents of Idyllwild have been through hell.
The fact is, my mind and heart were filled with turmoil, but I was not alone. All residents of Idyllwild scattered throughout Southern California and those who stayed were feeling the same way.
I stayed with friends Julie and Jim Kehl in La Quinta. Fortunately, they have a well-stocked bar and plenty of good wine. Thank you, my good, good friends.
Keeping in touch with the Town Crier staff was crucial for me, every two hours or so logging on to idyllwildtowncrier.com and watching for fire updates.
Back to the fire. This was not my first experience with a mountain fire. In 1996, the Bee Canyon Fire took its toll on Idyllwild minds. Evacuation was mandatory. All of the Town Crier staff managed to get back in time to put out a publication for the upcoming week.
Fires of this size have a way of getting into your soul, leaving residents lamenting about their suddenly uncertain future. "What next?" keeps going through my head.
With all said, I have my pets and I am healthy. All the belongings I left behind are just things and things can be replaced.
Idyllwild residents are resilient. We did it before and we can do it again. When we got back home, we hugged each other hello then got to work rebuilding our resort town's reputation.
Is Idyllwild a great little town or what?
Thank you, all firefighters and everyone involved, directly or indirectly, with putting out this fire monster. My heart is with each and every one of you.
No recipe in this column, just my heartfelt thanks.
Next column, how about Oven-Fried Chicken by the Bucket? Will try it out on Town Crier Staff first.
Love, from Lola's Kitchen.


text:
Accessibility tools
Service tools
Language selector
Navigation path
Left navigation
Additional tools
Other available languages: none
News from the Communication Directorate General's midday briefing
Nouvelles du rendez-vous de midi de la Direction Générale Communication
25 / 06 / 09
The European Commission has decided to bring Greece before the European Court of Justice on the basis of Article 228 of the EC Treaty. The Hellenic Republic has failed to take steps to comply with the Court's judgment of 18 December 2007 in Case C-481/06 on the conformity of Greek legislation, which allows a negotiated procedure to be used without a prior call for tenders for public contracts for the supply of certain types of medical equipment.
The European Commission has decided to send a formal request to the United Kingdom concerning the award of a public works concession contract by the City of York Council relating to the residential development of a piece of land known as "Osbaldwick". This formal request takes the form of a "reasoned opinion", the second stage of the infringement procedure laid down in Article 226 of the EC Treaty. If there is no satisfactory reply within two months, the Commission may refer the matter to the European Court of Justice.
The European Commission has formally requested Greece to amend its legislation requiring qualified EU teachers to have an excellent knowledge of the Greek language. This request takes the form of a reasoned opinion, the second phase of the infringement procedure as laid down in Article 226 of the EC Treaty. If there is no satisfactory reply within two months, the Commission may refer the matter to the European Court of Justice.
The European Commission has decided to take action to ensure that the Internal Market principles of free movement of services and freedom of establishment are respected in Greece and Germany. The Commission has decided to send formal requests to Greece concerning its rules on the establishment of service stations and to Germany concerning its requirements for actions relating to trademarks and patents. These formal requests take the form of 'reasoned opinions', the second stage of the infringement procedure laid down in Article 226 of the EC Treaty. If there is no satisfactory reply within two months, the Commission may refer the matter to the European Court of Justice. The Commission has also decided to send an official request for information to Germany concerning legislation that may restrict the establishment of retail facilities. This formal request takes the form of a 'letter of formal notice', the first stage of the infringement procedure laid down in Article 226 of the EC Treaty. If there is no satisfactory reply within two months, the Commission may proceed to a 'reasoned opinion'. Finally, the Commission has decided to close infringement proceedings against Austria in relation to restrictions on the free movement of bovine artificial insemination services.
The European Commission has decided to refer Ireland to the European Court of Justice over the exemption of the Irish Voluntary Health Insurance Board (VHI) from certain EU rules on non-life insurance. The referral follows the "complementary reasoned opinion" sent to Ireland in November 2008 (IP/08/1787), which requested Ireland once again to establish compliance with EU law. This follows a complaint to the Commission alleging that the VHI is unlawfully pursuing insurance activities without being subject to the First Non-Life Insurance Directive in particular.
The European Commission has decided to refer Austria, Ireland Italy and Spain to the European Court of Justice over non-implementation into national law of the Statutory Audit Directive. The Commission has also decided to send formal requests to Belgium, Ireland, Greece, Luxembourg, Poland and Portugal as they have failed to fully implement into their national laws the latest Directive in the field of accounting within the prescribed deadline. These formal requests take the form of "reasoned opinions", the second stage of the infringement procedure laid down in Article 226 of the EC Treaty. If there is no satisfactory reply within two months, the Commission may refer the matter to the European Court of Justice.
The European Commission has decided to refer the Czech Republic to the European Court of Justice and to send a formal request to Luxembourg over failure to implement into national law Directives in the area of company law and corporate governance. This formal request takes the form of a "reasoned opinion", the second stage of the infringement procedure laid down in Article 226 of the EC Treaty. If there is no satisfactory reply within two months, the Commission may refer the matter to the European Court of Justice. The Commission has also decided, under Article 228 of the EC Treaty, to send France a letter of formal notice requesting full information on its implementation of a 2009 Court judgment concerning a Directive on the recognition of professional qualifications.
The European Commission today closed three infringement proceedings against Poland after the country took steps at national level to correct the problems and bring Polish law into line with EU telecoms rules. The cases concern the independence of the Polish regulator, consumer contracts, and the obligation for operators to negotiate interconnection. The Commission is still analysing other parts of the amendments made by the Polish government to national telecoms laws.
Portugal must speed up delivery of comprehensive telephone directory and directory enquiry services, as required by EU telecoms rules, says the European Commission. In March 2009, the European Court of Justice (ECJ) called on Portugal to ensure that Portuguese consumers could rely on directory and directory enquiry services including the data of all telephone users that want to be listed. Today, the Commission has decided to send a letter of formal notice to Portugal asking it to comply with the judgement, Otherwise, Portugal could be fined if the case proceeds to the ECJ again.
The Commission today opened an infringement procedure against Germany because the country's national regulator - the Bundesnetzagentur - did not consult the Commission and other national regulators prior to deciding on new levels of mobile termination rates. Termination rates are wholesale fees charged by operators to connect calls from one network to another operator's network. Contrary to Germany's obligations under EU telecoms rules, the Bundesnetzagentur's final decisions on mobile termination rates were adopted on 31 March 2009 before the Commission and other national regulators had the possibility to comment on the level of these rates. This lack of transparency is a first in the application of EU telecoms rules in the 27 EU Member States. Without prior consultation of other regulators, there is an increased risk that the regulatory approach to termination rates will differ among Member States and distort competition in the EU's single telecoms market. Already today, termination rates, and the methodology used to set them, vary widely across the EU. The Commission has therefore called for them to be better coordinated (see IP/09/710).
The European Commission today launched legal action against Latvia over the administrative charges levied by the "Electronic Communications Office" (Elektronisko sakaru direkcija (ESD)), one of Latvia's national telecoms regulators. The Commission is concerned that the administrative charges collected from companies for controlling the usage of the radio spectrum are not imposed in an objective, transparent and proportionate way. The Commission therefore has decided to send a letter of formal notice, the first step in an infringement proceeding, to the Latvian authorities.
The location of people calling the single European emergency number 112 from their mobile phones in Lithuania is still not always available to emergency services, despite the European Court of Justice deciding, in its judgement last September that Lithuania is required under EU telecoms rules to make this happen. The European Commission therefore decided today to send a letter of formal notice to Lithuania calling on it to comply with the judgement by ensuring that caller location information is available to emergency services for all mobile calls to 112. Lithuania could be fined if the case proceeds to the European Court of Justice again. Caller location allows emergency services to pinpoint the location of 112 callers even if the caller cannot, making it much easier to respond to emergencies.
Today the European Commission stepped up legal action against Poland for wrongly transposing EU rules on the re-use of public sector information (PSI) into Polish law. Polish legislation does not contain crucial provisions of the EU's 2003 PSI Directive, including obligations on non discrimination and prohibition of exclusive agreements. As a result, wrong transposition prevents reusers to know the full extent of their rights established by the Directive and to rely on them before the national courts. In its reasoned opinion, the second step in the infringement procedure, the Commission asks Poland to take the necessary steps to comply with the EU rules on PSI within two months. If Poland does not comply with the PSI Directive within this time limit, the Commission can refer the case to the Court of Justice.
The Commission has requested information from Romania as regards its legislation on the application of a pollution tax on passenger cars. The Commission is of the opinion that the provisions of the Romanian legislation, according to which the application of the pollution tax for certain motor vehicles is suspended while it is increased for certain used cars coming from other Member States, might discriminate against used cars brought from other Member States and protect the domestic new car industry. The request takes a form of "a letter of formal notice" - the first stage of the infringement procedure laid down in Article 226 of the EC Treaty. If the Commission does not receive a satisfactory response within two months, it may proceed with the second stage of the procedure (to issue a reasoned opinion) and ultimately bring the case before the Court of Justice.
The European Commission has decided to refer Luxembourg to the European Court of Justice over its incorrect application of certain provisions of the Savings Tax Directive as regards interest payments made to beneficial owners who benefit from so-called "non-domiciled resident" status in their country of residence .
La Commission européenne adresse un deuxième avertissement écrit à la Belgique pour infraction à la législation communautaire relative au traitement des eaux urbaines résiduaires. En 2004, la Cour de justice des Communautés européennes avait estimé qu'aucune des régions belges ne disposait de systèmes de collecte et de traitement des eaux urbaines résiduaires suffisants. Ce deuxième avertissement fait suite à l'avertissement qui a été adressé à la Belgique au mois de janvier 2006. Si la réponse de la Belgique n'est pas satisfaisante, la Commission pourra demander que la Cour inflige des amendes à cet État membre.
The European Commission has formally requested Portugal to change its law since it is of the opinion that Portugal does not apply a flat rate scheme for farmers consistent with the objectives of the scheme which is laid down in the VAT Directive. As a result farmers opting for the flat rate scheme may face financial disadvantages. The request takes the form of a reasoned opinion (second step of the infringement procedure provided for in article 226 of the EC Treaty). If the relevant national legislation is not amended in order to comply with the respective reasoned opinion, the Commission may decide to refer the matter to the European Court of Justice.
The European Commission has formally requested the United Kingdom to amend its legislation governing the VAT exemption for transactions related to aircraft, since it is based on criteria different from, and inconsistent with, those employed in the VAT Directive. The request is communicated in the form of a 'reasoned opinion' (second step of the infringement procedure provided for in Article 226 of the EC Treaty). If, within two months, the relevant national rules are not amended in order to comply with the reasoned opinion, the Commission may decide to refer the matter to the European Court of Justice.
The European Commission has sent Belgium a formal request to amend its legislation which leads to different taxation of interest depending on where the bank paying such interest is established. According to the Belgian legislation, interest paid by Belgian banks to individuals is exempted from tax up to the amount of € 1660 whereas interest paid by foreign banks cannot benefit from the same exemption. The Commission's request takes the form of a 'reasoned opinion' (second step of the infringement procedure of Article 226 of the EC Treaty). If Belgium does not reply satisfactorily to the reasoned opinion within two months the Commission may refer the matter to the European Court of Justice.
The European Commission has sent Finland and Denmark formal requests to amend their legislation which leads to discriminatory taxation of foreign pension funds. The Commission's requests take the form of a 'reasoned opinion' (second step of the infringement procedure of Article 226 of the EC Treaty). If Finland and Denmark do not reply satisfactorily to these reasoned opinions within two months the Commission may refer the matter to the European Court of Justice.
The European Commission has formally requested Spain to change its tax provisions concerning the taxation of capital gains arising from an exchange of shares. The Commission considers some of these provisions to be incompatible with the "Merger" Directive (Council Directive 90/434/EEC) and with the freedom of establishment and the free movement of capital as laid down in Articles 43 and 56 of the EC Treaty and the corresponding articles of the EEA Agreement. The request takes the form of a reasoned opinion (second step of the infringement procedure provided for in Article 226 of the EC Treaty). If there is no satisfactory reaction to the reasoned opinion within two months, the Commission may decide to refer the case to the Court of Justice of the European Communities.
The Commission decided today to ask the European Court of Justice (ECJ) to impose a periodic penalty payment and a lump sum on the Hellenic Republic which failed to comply with the ruling of the ECJ on 18 July 2007 in Case C-26/07, Commission v. Hellenic Republic. The judgment of the Court had stated that the Hellenic Republic failed to fulfil its obligations under Article 18 of Directive 2004/80/EC relating to compensation to crime victims which requested Member States to notify to the Commission national measures for the implementation of the Directive.
Mariann Fischer Boel, the European Commissioner for agriculture and rural development is today announcing the three winners of the 'Milk Power!' competition during a visit to a school in Paris. This competition is part of the 'Milk – Drink it up!' European campaign, which aims to inform Europeans about the benefits of milk and dairy products as a healthy alternative to junk food and drinks.
The European Commission today set out plans to finance the demonstration of carbon capture and geological storage (CCS) in cooperation with China. This comes in the context of a commitment made by the EU and China to develop and demonstrate in China and the EU advanced, near-zero emissions coal technology through carbon capture and storage by 2020. CCS is an important technology in the fight against climate change and has the potential to cut emissions from power generation in fast-developing and coal-dependent emerging economies, such as China.
La Commission européenne a adopté aujourd'hui des avis motivés à l'encontre de trois États membres de l'Union européenne qui n'ont pas encore notifié les mesures de transposition en droit national d'une directive communautaire relative au permis de conduire.
La Commission européenne a envoyé aujourd'hui un avis motivé – la dernière étape avant une éventuelle saisine de la Cour de justice – à la Slovaquie pour ne pas avoir transposé correctement une directive communautaire dans le domaine de la sécurité maritime. La Directive en question établit les règles communes concernant les organismes habilités à effectuer l'inspection et la visite des navires.
La Commission européenne engage des poursuites judiciaires contre la Grèce parce que cet État membre n'a pas mis en place les mesures adéquates pour protéger l'une des zones humides les plus importantes d'Europe. L'affaire concerne la pollution et la dégradation du lac Koroneia, dans la région de Thessalonique. Un premier avertissement est envoyé à la Grèce pour manquement à l'obligation de mettre en œuvre le cadre juridique nécessaire pour assurer la protection et la conservation du site.
Danuta Hübner, Commissaire européenne à la politique régionale, sera en visite le 26 juin dans la région Limousin. La Commissaire rencontrera Mme Evelyne Ratte, le Préfet du Limousin, M. Jean-Paul Denanot, le Président de la Région, ainsi que M. Alain Rodet, le Député-Maire de Limoges. Elle découvrira comment la région a choisi d'orienter les investissements européens vers l'innovation, en particulier dans le domaine de la céramique qui a fait sa réputation.
The European Commission has addressed formal requests under the EC Treaty infringements procedure to Belgium and the United Kingdom to communicate measures implementing the Commission Directive 2005/81/EC amending the Directive on the transparency of financial relations between Member States and public undertakings (80/723/EEC - see IP/00/763). Member States were required to implement the Directive in national law by 19 December 2006. The requests take the form of "reasoned opinions", the second step in infringement procedures under Article 226 of the EC Treaty. Belgium and the UK now have two months to notify to the Commission the measures they have taken to implement the Directive. Failing this, the Commission may refer them to the European Court of Justice.
The European Commission has decided to refer Italy to the European Court of Justice (ECJ) for failure to implement a 2004 ruling by the Court of Justice (case C-99/02) confirming a Commission decision of 1999 finding that Italy had granted illegal and incompatible aid and ordering its recovery. The illegal aid in question took the form of exemptions from social security contributions in cases where companies could not prove that new jobs had been created or prove that the workers hired had special difficulties entering or re-entering the employment market. Although over five years have elapsed since this judgement, Italy has still only recovered a small part of the overall aid amount estimated at about 281 million euros. The Commission therefore now requests the ECJ to impose fines on Italy under Article 228 of the EC Treaty.
Today the European Commission sent letters of formal notice to the Czech Republic, Estonia, Greece, Latvia, Luxembourg, the Netherlands, Poland, Portugal, and Slovenia for inadequate transposition of Directive 1999/44/EC on certain aspects of the sale of consumer goods and associated guarantees into their national law, since it has concerns that their national laws may not be sufficient to implement the Directive.
The Commission has today sent a reasoned opinion to Latvia on its implementation of EU rules prohibiting discrimination in employment and occupation on the grounds of sex (2002/73/EC). The Latvian authorities have two months to respond. If they fail to reply or if the response is unsatisfactory, the Commission may decide to take the case to the European Court of Justice (ECJ) (see also MEMO/08/742).
The European Commission has decided to take legal action against Italy for failure to comply with a European Court of Justice (ECJ) ruling on differences in the pension age for male and female civil servants. It will send Italy a "letter of formal notice" under Article 228 EC over the country's failure to follow a Court ruling last year that current Italian provisions violate the principle of equal pay for men and women.
The Commission has taken firm action today against 25 Member States who prevent European consumers benefiting from the advantages of a competitive and open Energy Market by not complying with EU legislation. Austria, Belgium, Bulgaria, the Czech Republic, Denmark, Germany, Estonia, Spain, Finland, France, Greece, Hungary, Ireland, Italy, Lithuania, Latvia, Luxembourg, The Netherlands, Poland, Portugal, Romania, Slovenia, Slovakia, Sweden and the United Kingdom will be receiving letters of formal notice for not complying with applicable gas and electricity regulations. The Commission has also sent letters of formal notice to Greece, Poland, Portugal, Romania and Lithuania for maintaining a system of regulated prices in violation of the EU directives on electricity and gas.
The Commission has today referred Estonia to the European Court of Justice (ECJ) for non-transposition of EU rules prohibiting gender discrimination in access to and supply of goods and services (Directive 2004/113/EC). Estonia has not yet adopted all the necessary measures to give effect to the legislation in national law, despite a 'reasoned opinion' (second stage warning) sent by the Commission in February 2009.
The Commission has today sent reasoned opinions to nine Member States for failing to communicate national measures to transpose Directive 2005/47/EC on working conditions in the international rail sector. The countries concerned are Portugal, Germany, Estonia, Greece, Ireland, Italy, Latvia, Luxembourg and France. They now have two months to respond.
President Barroso and Energy Commissioner Andris Piebalgs have welcomed today's adoption of new rules on the internal energy market by the Council following a positive vote by the European Parliament in April. The new legislation is expected to strengthen the EU's internal energy market, give consumers more protection and the benefit of the lowest possible energy prices while offering companies the chance to compete on a level playing field. In addition the legislative package will promote sustainability by stimulating energy efficiency. Member States now have 18 months to transpose the new rules into national law.
Today's adoption by the Council of the Nuclear Safety Directive is a major step for achieving a common legal framework and a strong safety culture in Europe. The EU has thus become the first major regional nuclear actor to provide binding legal force to the main international nuclear safety standards, namely the Safety Fundamentals established by the International Atomic Energy Agency (IAEA) and the obligations resulting from the Convention on Nuclear Safety . The Directive also reinforces the independence and resources of the national competent regulatory authorities.
The European Commission today said Lithuania is failing to put in place EU rules that guarantee the independence of national telecoms regulators. It stepped up legal action by deciding to send a reasoned opinion (the second phase of an infringement proceeding). The Commission wants a distinct separation between those making the rules and owners or providers of telecoms services. The Commission started legal action by sending a letter of formal notice in September 2008 (IP/08/1343). However, the Lithuanian authorities did not address the Commission's concerns in their response. For this reason the Commission is now launching the second phase of the infringement proceeding.
Based on first preliminary estimates for 2008, Gross Domestic Product (GDP) per inhabitant expressed in Purchasing Power Standards (PPS) varied from 40% to 253% of the EU27 average across the Member States. In France, Spain, Italy, Greece and Cyprus, GDP per inhabitant was within 10% of the EU27 average. Austria, Sweden, Denmark, the United Kingdom, Finland, Germany and Belgium were between 10% and 30% above the average, while the highest levels of GDP per inhabitant in the EU27 were recorded in Luxembourg, Ireland and the Netherlands. Slovenia, the Czech Republic, Malta, Portugal and Slovakia were between 10% and 30% lower than the EU27 average. Estonia, Hungary, Lithuania, Poland and Latvia were between 30% and 50% lower, while Romania and Bulgaria were between 50% and 60% below the EU27 average. These figures for GDP per inhabitant, expressed in PPS, are published by Eurostat. They cover the 27 EU Member States, the three candidate countries, three EFTA Member States and four Western Balkan countries.
In April 2009 compared with March 2009, the euro area (EA16) industrial new orders index fell by 1.0%. In March the index decreased by 0.2%. In the EU271 new orders declined by 0.5% in April 2009, after dropping by 0.5% in March. Excluding ships, railway & aerospace equipment, for which changes tend to be more volatile, industrial new orders decreased by 0.9% in the euro area, but increased by 0.3% in the EU27. In April 2009 compared with April 2008, industrial new orders decreased by 35.5% in the euro area and by 35.0% in the EU27. Total industry excluding ships, railway & aerospace equipment dropped by 35.3% in the euro area and by 33.8% in the EU27. These estimates are released by Eurostat.
The European Commission has granted clearance under the EU Merger Regulation to the acquisition of joint control of Hulu LLC of the US by General Electric (GE), News Corporation (NewsCorp) and The Walt Disney Company (Disney), all of the US. GE is active in infrastructure, industrial products, finance, healthcare, media and entertaining. NewsCorp is active in entertainment, television, newspapers, magazines and book publishing. Disney is an entertainment and media company. Hulu broadcasts TV and film entertainment over the internet. The operation was examined under the simplified merger review procedure.
The European Commission has authorised, under EC Treaty state aid rules, a six month prolongation of a Spanish guarantee scheme for credit institutions. The Commission found the prolongation of the measures, initially approved on 23 December 2008 (see IP/08/2049), to be in line with its Communication on state aid to overcome the financial crisis (see IP/08/1495). In particular, the extended measures are limited in time and scope. The Commission has therefore concluded that they represent an appropriate means of remedying a serious disturbance in the Spanish economy and as such are compatible with Article 87(3)(b) of the EC Treaty.
László Kovács, the Commissioner responsible for Taxation and Customs said: "I welcome today's agreement which waives the obligation for traders to provide customs with advance electronic information for security purposes in bilateral trade between Switzerland and the EU. With an average of 23.000 lorries and 4.400 train wagons per day crossing our common borders, we both have a strong mutual interest in implementing equivalent customs security measures in order to increase security for our citizens while not disrupting trade." The agreement therefore foresees that, Switzerland will implement in its trade with third countries customs security measures that are equivalent to those applied by the EU. This implies mutual recognition of systems of risk analysis and management and of systems to facilitate reliable traders (the so-called EU AEO certificate). This will ensure both smooth trade flows between Switzerland and the EU and a high level of security of the supply chain. The agreement will enter into force on 1 July 2009. Further information on the agreement can be found at: http://ec.europa.eu/taxation_customs/common/legislation/proposals/customs/index_en.htm Further information on the security aspects of the Customs Code can be found at: http://ec.europa.eu/taxation_customs/customs/policy_issues/customs_security/index_en.htm
Today, Joe Borg, European Commissioner for Maritime Affairs and Fisheries, will visit Noord-Holland, the Netherlands, and attend a conference on "Sustainable Innovation for the North Sea Region", organised by the North Sea Commission of the Conference of Peripheral Maritime Regions (CPMR). Ahead of his visit, Mr Borg said, "As the Noord-Holland province is surrounded by water, it is an ideal setting for discussing coastal and maritime affairs. Noord-Holland and its stakeholders share unique insight and know-how and are ideally placed to contribute to integrated policy-making at regional and national level alike. Moreover, the CPMR has been a consistent supporter of the European Union's Integrated Maritime Policy, while the North Sea Commission is one of its bodies whose valuable work on projects has helped put that policy into practice". In his address to the conference, Commissioner Borg will point to integrated coastal zone management and maritime spatial planning, a key tool developed under the European Union's Integrated Maritime Policy (IMP). Both can be used as means of delivering coherent and integrated governance, planning and climate change mitigation in coastal areas particularly in places such as the North Sea region, which has in fact been exploring spatial planning and co-operation for some time now. He will also advocate customised sea-basin strategies under the IMP umbrella as a means of stimulating growth and jobs, while simultaneously triggering profound improvements in environmental sustainability.
The European Commission has sent "Reasoned Opinions" to the governments of Czech Republic and Poland over their failure to notify national implementing measures as required by Directive 2007/72/EC. This Directive amends Council Directive 66/401/EEC as regards the inclusion of the species "Galega orientalis Lam." on the marketing of fodder plant seed. The sending of a "Reasoned Opinion" is the second step in infringement proceedings under Article 226 of the EC Treaty. If the Member States concerned are not able to assure the Commission that this Directive is in fact transposed under their national law, the next step will be for the Commission to lodge cases against them with the European Court of Justice.
The European Commission has sent "Reasoned Opinions" to the governments of Czech Republic, Italy, Portugal, Finland and United Kingdom over their failure to notify national implementing measures as required by Directive 2008/109/EC. This Directive lays down protective measures against the introduction into the Community of organisms harmful to plants or plant products, and against their spread within the Community. The sending of a "Reasoned Opinion" is the second step in infringement proceedings under Article 226 of the EC Treaty. If the Member States concerned are not able to assure the Commission that this Directive is in fact transposed under their national law, the next step will be for the Commission to lodge cases against them with the European Court of Justice.
The European Commission has decided to refer Belgium, Austria and Portugal to the European Court of Justice (ECJ) over their failure to notify national implementing measures as required by Commission Directive 2008/53/EC. This Directive amends the list of aquatic animal diseases, established by Council Directive 2006/88/EC, which lays down animal health requirements for aquaculture animals and products. Member States were obliged to implement the Directive by 1 August 2008. In February 2009 the Commission sent "Reasoned Opinions" to five Member States that had still not notified it of the measures taken under their national law to implement the Directive. Three of them, Belgium, Austria and Portugal, still haven't taken any measures to implement the Directive. An ECJ judgement against the Member States will oblige them to take action or risk financial penalties.
The European Commission decided today to further pursue an infringement procedure against Sweden, that has not complied with the provisions of Commission Decision 96/78/EC laying down common zootechnical criteria for access to stud-book for equidae (horses, donkeys and other members of the "equine" family). In 2008 the Commission, following an assessment, determined that rules promulgated by the entity in charge of maintaining stud-books for the breed called "Swedish trotters", are incompatible with EU legislation. The rules are incompatible because the conditions for access to this stud-book are not laid down on the basis of the merit and the breeding value of the individual horses. Notably, some of the current rules discriminate against horses born in other Member States. As the Commission has not received any amended version or draft of these rules, it has decided to send a Reasoned Opinion to Sweden in order to achieve compliance with EU law.
The European Commission has decided to refer Spain to the European Court of Justice (ECJ) over the incorrect transposition of Community legislation on plant protection products with regard to data protection. Directive 91/414/EEC concerning the placing of plant protection products on the market provides that a plant protection product may only be placed on the market and used if it is authorised by the competent authorities of a Member State. These authorities grant authorisations on the basis of a dossier submitted by the applicant. As the preparation of studies for such dossier is expensive, Article 13 of the Directive provides for a data protection period of 5 or 10 years. During that period other applicants wishing to obtain an authorisation have to duplicate the protected studies or to reach an agreement with the owner of the studies on their use. The Spanish legislation goes beyond the provisions of Directive 91/414/EEC by allowing national authorities to use studies that are protected without the agreement of the first applicant. As a result, the Spanish legislation is incompatible with the above Directive. Since Spain did not amend its legislation, the Commission decided to refer the case to the ECJ. The referral of the infringement case to the Court may lead to a declaration that the Member State concerned has failed to fulfil an obligation under the EC Treaty and, at a later stage, if the infringement persists, to condemning the Member State to pay a lump sum and/or financial penalty.
The European Commission decided today to address a reasoned opinion to the United Kingdom because it considers that current UK rules on food irradiation are incompatible with Directive 1999/2/EC on the approximation of the laws of Member States concerning food and food ingredients treated with ionising radiation in that they authorise national authorities to recognise food irradiation facilities in third countries. According to Directive 1999/2/EC one of the conditions for importing a foodstuff treated with ionising radiation from a third country is that it was treated in an irradiation facility approved by the Community. The Commission recognises that the United Kingdom has so far not used this possibility and is in the process of amending its legislation in the field of food irradiation. However, since a letter of formal notice was sent already in March 2007 and since there have been considerable delays in the process leading to the adoption of new regulations in the UK, it was necessary to issue a reasoned opinion to ensure expedited compliance.
The European Commission today decided to send a 'Letter of Formal Notice' to Germany for failure to publish the details of all beneficiaries of the Common Agricultural Policy. Under EU law, details on all recipients had to be published on the internet by 30th April 2009. Earlier this month, the Federal Government announced that the data were finally available online, but the Land of Bavaria has decided not to publish. In these circumstances, the Commission has no choice but to start an infringement procedure against Germany. A Letter of Formal Notice is the first step in infringement proceedings under Article 226 of the EC Treaty. Germany has one month to respond to the letter. If the Commission is still not satisfied after this first step, it will send a 'Reasoned Opinion'. If Germany still proved unable to ensure the full implementation of the Regulation, the next step would be for the Commission to lodge proceedings against it with the European Court of Justice.
• Memo Questions and Answers on the Communication on Demonstrating Carbon Capture and Geological Storage (CCS) in emerging developing countries: financing the EU-China Near Zero Emissions Coal Plant project
• Memo on Energy infringements. Country fact sheets
• Memo Q&A: the infringement exercise concerning cross-border energy network access and regulated prices
• Speech by President Barroso: "European energy policy for the 21st century", Berlin
• Speech by Commissioner Reding 'Towards a European Strategy of High Speed Broadband for All: How to Reward the Risk of Investment into Fibre in a Competitive Environment', Brussels
• Speech by Commissioner Borg "Working together to care for our coasts and seas", Harlem, The Netherlands
A disposition au secrétariat de Jonathan Todd (BERL 03/315):
Notification préalable d'une opération de concentration :
Fortis Private Equity/Kuiken
Side Bar


text:
There's not one, so I'll start it.
I really enjoyed watching this game last night. I don't know why. I'm sure it's a combination of lowered expectations, the Blazers being my second favorite team, and a more varied offense.
I thought our offense looked better without Danny on the floor. There were far fewer early long-range jumpers. We fed Hibbert in the post far more often. There was a bit more ball and player movement. It was nice to watch. Portland is an excellent defensive team, and we managed to play some pretty fantastic offense for 2 quarters (2nd, 3rd).
Here are my thoughts:
Our starting lineup sucks. I'm not going to go back and do the research right now, but how many games in a row have we basically been run off the floor during the first 5 minutes of the game? It's seems like it happens pretty much every night. Then we bring in some bench guys, do a pretty good job of playing catch-up for 2 quarters, and then fade down the stretch.
LaMarcus Aldridge is good. I know he scored 10 points in a row with Troy trying to guard him, but I think that says more about Aldridge than it does about Troy. He was hitting some very difficult shots. I wouldn't go so far as to say that Troy was playing good defense on him, but Murphy wasn't just giving up dunks or wide open jumpers. If Aldridge is going to hit turnaround jumpers like that, there are only 5-6 guys in the NBA who are going to be able to slow him down, and none of them are on our roster.
Brandon Roy is good. I hope Danny watched the 4th quarter. That's how the best player on a team is supposed to play when the game's close.
AJ Price deserves minutes. The 2-10 shooting was a bit of an anomaly. We all know the kid can shoot. His pass to Dunleavy was probably one of the best 3 passes we've seen from all season. I'd be 100% happy with a Watson-Price PG tandem for the rest of the year.
I think Hibbert got hurt in the 3rd quarter. The TV showed him on the bench wincing and talking to some trainers. At least that's how I'm choosing to explain him not coming back in the game when he was playing pretty well.
Rush played pretty well in the 2nd half yesterday. I'm hoping we'll see a turnaround while Danny's out. He got in to a nice little tete-a-tete with Brandon Roy for a couple possessions. He wasn't able to stop Roy (not many can) but he was able to score on him twice in a row.
Why can't Foster and Hibbert play together? That makes more sense than Hansbrough-Murphy. It's not like Jeff is totally locked in to the center position.


text:
Monday: SRD.
Little one talked me into going to the Y.
- reverse leg-press
- leg extension
- unweighted eccentric calf raises
- high knees
- butt kicks
- scooter [back kicks]
Monday: SRD.
Little one talked me into going to the Y.
I did Pilates class tonight.
Harbourboy: Good to see you post! Nice streak! Last I heard you had two kids?
tww: Nice run as always! Your streaks themselves are amazing enough; but what has always impressed me is your average distance run and your pace!!
fittest: That was a nice distance for me coming off of a 50K. I wasn't sure I could run "fast" (relatively speaking of course). I haven't tried since November or so. But I was very pleased with my effort. I was 86 out of 273 finishers.
ElB: I think that is how it traditionally works when they offer a 5K and a 10K option. The first time I won my AG it was in such a race. I picked the 5K and all the fast guys my age ran the 10K. LOL I kept the medal anyway.
Moth: Nice activity on an SRD! You have to go workout when one of your kids wants to. He'll be grown and gone before you know it!
Annie: Hope all is well with you! You are missed!!
fittest: That was a nice distance for me coming off of a 50K. I wasn't sure I could run "fast" (relatively speaking of course). I haven't tried since November or so. But I was very pleased with my effort. I was 86 out of 273 finishers.
FittestOver40, those were some outstanding times and distances in your pentathlon. 8-10 year ago I could have competed with you on the running events, definitely NOT on the throwing... plus you are a lot closer to 50 than 40, and so very well done! What is next?
Tww, FF, HarborBoy... and now FlyinFree... I enjoy the streaking talk, although this is not something I could ever commit to. FlyinFree... got to hand it to you for being public about your intentions, even though you have a ways to go before being classified as a serious streaker... does not mean you won't get there. The public declaration should help, if there are days when you don't feel like doing it. I also applaud the running commute.
Congrats on the mini-streak, too, MySolitude. I am not quite ready to completely give up on the short stuff, but I am getting there.
Good for you George, for running and biking with DW and DD over the week-end. Any run today?
pretty routine day for me... busy at work, and then an 8.7 miler in nice conditions in the early evening. I ran around Portland, which was loaded with runners... probably why I ended up with a slightly faster pace than normal, averaging 7:56.
Good Evening Masters,
Late day for me. 5.1 easy miles this evening, its been awhile running after sunset. Shower and late dinner - till tomorrow.
mysol - yes and had some extra time for some extra miles.
BOSNPM - thanks - I do enjoy the warmer temps for running.
Rick - run squeezed in.
Catch up tomorrow.
Be Well.....
Congratulations you big stud!
RCL.......Nice pace on the 7.8 miler........when you mention running commute it reminds me of Planet W.
George.......Nice and easy 5.1 miler.


text:
As the NHL lockout lurched into its sixth day Friday, with nary a hint of when negotiations between the league's owners and players might resume, another option opened for the forcefully unemployed athletes thanks to a ruling from the Swedish government.
The Competition Authority issued a ruling in Stockholm that the Elitserien's ban on NHL players during the lockout is illegal, and although an appeal from the Swedish league is a possibility, reports surfaced almost instantly of teams and players negotiating contracts, including Vezina Trophy winner Henrik Lundqvist and Norris Trophy winner Erik Karlsson.
SVT in Sweden reported that the two decorated Swedes are in negotiations with the Frolunda Indians, quoting the club's director, Anderz Larqvist, to that effect. Frolunda also is in talks with Dallas Stars winger Loui Eriksson, while Brynas chases the Washington Capitals duo of Nicklas Backstrom and Marcus Johansson.
If the Swedish league appeals, and NHL players wind up barred from playing there after all, locked-out NHL players still have plenty of international options. Leagues in Russia, Finland, the Czech Republic, Switzerland, Germany and Slovakia have thrown their doors open, as has Sweden's second division, the HockeyAllsvenskan, where Los Angeles Kings star Anze Kopitar figures to skate circles around the competition for Mora IK, his brother's team.
These players are perfectly within their rights to pursue employment opportunities elsewhere while the NHL prohibits them from plying their trade on North American ice. Players who decide not to play for a team outside the NHL also have that right.
"Some won't go to Europe because they have family obligations at home," agent Matt Keator told USA Today earlier this week. "Others won't go because the cost to insure their current contracts are too high and some will just go to play and stay sharp for when this all passes."
The insurance issue may be one of the reasons Sidney Crosby has yet to figure out what he's doing. On Wednesday afternoon, Crosby's agent, Pat Brisson, told Fan 590 radio in Toronto it would cost up to $400,000 per month to insure only part of his client's contract.
For all the outrage over NHL players "taking jobs away" from their European counterparts, the insurance kerfuffle gets lost in the shuffle. The jobs issue is a natural factor of economics—with the NHL cutting 600 hockey-player jobs in North America, the effect will be felt throughout the global hockey economy; Ilya Kovalchuk and Evgeni Malkin depriving a fourth-liner the chance to play in the KHL is hardly that different from the Carolina Hurricanes sending 2011 Calder Trophy winner Jeff Skinner to the AHL, denying someone an opportunity to skate with the Charlotte Checkers.
The insurance worries are more emblematic of what is really at stake in the NHL lockout: large piles of money. Are people really supposed to feel bad because Crosby, who signed a 12-year, $104.4 million extension this summer, or any other player, might have to pay high insurance premiums to play hockey somewhere else? Boo hoo.
In New York, the registration fee for the Fall Adult Ice Hockey League at Chelsea Piers is $9,300 per team – which works out to about $850 per person on a team of 11. While that's a far cry from $400,000 a month, rec league players don't have nine-figure contracts, and that $850 is not going to cover equipment and medical bills. Playing hockey, as any NHL owner will tell you, is not cheap.
Professionals do not have to worry about equipment or medical bills, and paying those insurance premiums allows the locked-out NHL players to get paid to play somewhere else, always with the possibility that the owners of their lockout way stations will pick up the tab for the insurance. That's a far more appealing option than anything available to the laid-off employees of the Florida Panthers, whose Tuesday purge included their mascot, Stanley C. Panther.
It's the players' right and prerogative to find work wherever they can get it. That does not mean that fans, who have been overwhelmingly supportive of the NHLPA in the labor strife, have to sympathize with them all the way to Sweden, or Russia, or wherever they go. NHL fans just hope those insurance policies don't need to be paid out, and that the world's best players return to their home rinks in North America in good health. Sooner rather than later.


text:
Comedian Russell Brand was booted from a GQ Awards afterparty Tuesday after making Nazi jokes, according to MSN.com.
Brand was receiving the Oracle of the Year award at the annual ceremony in London when he told the crowd that the evening's sponsors, German fashion company Hugo Boss, had produced uniforms worn by Nazi troops during World War II.
"If any of you know a little bit about history and fashion, you'll know it was Hugo Boss (who) made the uniforms for the Nazis," Brand said. "The Nazis did have flaws, but they did look (expletive) fantastic, let's face it, while they were killing people on the basis of their religion and sexuality."
Brand later impersonated Hitler by putting a finger under his nose. "I'm a comedian, and it's my job to make jokes about things. Hugo Boss, it's fair enough, he might not have known! 'We're selling a lot of these (expletive) (uniforms), they're flying off the shelves!' Don't take life too seriously, soon we'll all be in the grave. Oh (expletive)!"
Organizers supposedly had Brand ejected from the afterparty. Brand defended himself later on Twitter, writing about the conversation he had with GQ magazine's editor Dylan Jones. "GQ editor: 'What you did was very offensive to Hugo Boss.' Me: 'What Hugo Boss did was very offensive to the Jews.' GQ Awards nazitailor."


text:
Defense is not all about effort. It certainly helps. Big Al will still get owned a lot even if he tried harder on defense, but he would get more stops.
Foye plays really hard on defense, but he's just too short to guard elite and/or bigger 2 guards. I'd really like to see Foye play more at the 1. He is a good passer.


text:
Micro-GPS trackers are good for parents, but a target for hackers
SEATTLE -- The first three hours after a child goes missing are the most critical, according to the National Center for Missing and Exploited Children. Of the children found murdered, experts believe it usually happened in the first three hours after the abduction.
Several companies are now marketing portable, micro-GPS trackers to anxious parents who want to know where their kids are at all times. The devices are small -- no bigger than three inches long -- and use GPS satellites, WiFi and cellular networks to update its whereabouts.
But at least one expert says the devices are vulnerable to hackers.
Products such as AmberAlertGPS, eTrak and eZoom are targeting families with 2- to 10-year olds, pre-cell phone age children. But you don't need to have a kid to use them.
The devices can be used to track a cheating spouse, a wandering employee or an elderly grandparent with Alzheimer Disease. But it's worried parents who seem to be fueling the growth of these tracking devices.
In 2007, the founder of AmberAlertGPS, Russ Thornton, lost his 3-year-old son at an amusement park.
"As a father you're worst fear is losing a young child," Thornton said.
He found his son after a frantic 45-minutes search. The incident prompted him to create AmberAlertGPS.
"I thought there has to be a way to give parents some piece of mind about there their children are," he said.
With AmberAlertGPS, parents can log into a website and see on a map where the device is located in real time. Using a "breadcrumb" feature, a parent can track the path of the device over a period of several days.
Users can set up custom zone alerts. Should the device enter or exit an area of the parent's choosing, an immediate email or text message is send to the parent.
Speed limits could be set incase the person with the device gets in a vehicle. If the device goes faster than a set speed, an immediate alert is set to the parents.
The same goes for registered sex offenders. If the device passes within 500 feet of a registered sex offender's address of record, parents can be alerted of the that too.
The AmberAlertGPS can also be used for communication. The child can press an SOS or panic button on the device, which places a cell phone call to a number registered to the account. That can be a parent's cell phone. Since the device has both a speaker and a microphone, the parent can have a conversation with the child.
But the parent can also call the device and listen in to what is happening to the child at any moment. The child or whoever is in possession of the device would never know the unit is now an eavesdropping device.
The only way they know if someone is listening is if the caller speaks up, because the device doesn't have a ring tone. If the caller mutes their phone, the holder of the device would never know someone is evesdropping.
Security expert Don Bailey has been investigating vulnerabilities with micro-GPS devices and how they interact with the cellular networks.
"The devices themselves can be designed with a reasonable amount of security and the network itself has a reasonable amount of security but when you pair these two things together, sometimes security falls through the cracks," Bailey said.
Bailey is the CEO of Capitol Hill Consultants and is a well recognized computer-security consultant that has exposed vulnerabilities with internet connected cars.
"With a very small amount of equipment for only a couple thousand dollars, they absolutely can intercept transmissions from the device to the network," he said.
The devices have lots of protocols to deal with, and Bailey said cellular carriers need to spend more money to strength security to make transmissions more immune to hackers.
"Allot of these devices really won't be secure for quite some time," he said.
Thornton defends the security of AmberAlertGSP, saying the necessary SSL and related security protocols are built into the device.
"We feel confident we can keep the integrity of that data secure and we don't feel there's an issue using our device in any way," Thornton said.
David Cassels recently spent a weekend with an eTrak device in his coat jacket. ETrak is another company marketing a micro-GPS tracker to parents. It offers similar features to the AmberAlertGPS, except it does not have two-way voice communications.
A father of three small kids, Cassels is typical parent who spends his weekend doing errands and taking his kids to soccer games and play dates. He's trying to decide if wants to track his kids.
"There's a feeling of security that if something were to happen, you would know where they are," he said.
But when asked about the possibility of someone intercepting the device's transmissions or stealing the user name and passwords, Cassels said the benefit may outweigh the risk.
"I think the purpose it serves is more valuable than the risk I might face of somebody get access to that information," he said. "You know that kids have their Facebook profiles and people have more an idea where they are based on that and it takes allot less effort than to access this data."
ETrak says it uses the best encryption available for its transmissions.
"The odds of it getting hacked are pretty low, said eTrak CEO John Harris.
Harris says eTrak operates the same way a cell phone or text message is transmitted.
"If the person has the ability to hack one's phone and get their information, they could potentially do the same with any other device around," he said. " Frankly, we are at the mercy of the network and their security devices."
Micro-GPS tracking units typically run between 100 and 200 dollars each and require a monthly subscription which run between $10 and $25 per month.


text:
AOL Search
Skip over navigation
Search the Web
Trending Topics
Senate cancels meeting
Fund hits $1T in value
Kalashnikov statue
Expels NK ambassador
Fuel shortage in NZ
Billboard removed
$16B in unpaid bills
Facing felony charges
Accidental attack
Microchip breakthrough
Mass grave found
NFL judge investigated
'Phantom' balk call
Unhappy with lawyers
James Blake testimony
To take Amazon returns
Can sue Rolling Stone
Final 747 flight
McAdoo: 'Sloppy play'
DNA clue to '92 murder
Out for 2017 season
WWI sub wreck found
Amended deal OK'd
Addresses Spicer kiss
Adidas passes Jordan
Wisconsin law upheld
Sprint, T-Mobile deal?
Judges threatened
Georgia campus protest
UN: 40M enslaved
Fatal outbreak trial
'Animal mill' ban
Collins back to Bulls
Rhino horns burned
Funding scholarships
Nerf gun eye injuries
Asteroid belt origin
Delayed hack reveal
Hit by line drive
Ram pickup recall
Lakers sign Bogut
Playing before 12 risk
Maria hits Caribbean
Trump speaks to UN
Mexico City earthquake
© AOL Inc. All Rights Reserved.
Terms of Use
Contact Us


text: Cotton poplin pajama set Item F8566 Color: BOLD PERI Size: All sizes are US sizes. SMALL MEDIUM LARGE X-LARGE Size Charts Quantity: 1 2 3 4 5 6 7 8 9 Prices do not include taxes. Add to Bag Wishlist Add to Bag Add To Wishlist share: size & fit S (fits waists 28-30); M (fits waists 32-34); L (fits waists 36-38); XL (fits waists 40-42). 32 1/2" inseam. Product Details The can't-go-wrong classic for every guy. This pajama set is cut slim because we know that slimmer doesn't mean less comfortable—just less sloppy. Pro tip: Get your monogram on the shirt as a form of ID in case you wander off sleepwalking. Cotton. Fly front. Elastic waistband. Machine wash. Import. Online only. Item F8566.


text:
Hanson makes statement with four strong innings
GLENDALE, Ariz. -- Right-hander Tommy Hanson advanced his rotation candidacy by allowing just one run over four innings for the Rangers against the White Sox on Tuesday. He also showed why he could be an asset as a long reliever.
Hanson did not start the game. Instead, he entered in the fourth inning and allowed one run on two hits, a walk and two strikeouts. His biggest transgression was a walk to start the fourth that ended up scoring.
"He really maneuvered the baseball," manager Ron Washington said. "He changed speeds, he had a curveball working and his fastball was down. The more he gets the baseball, the better feel he'll have for what he is trying to do."
Hanson is one of eight candidates for two spots in the Rangers' rotation. They want two starters to emerge but they also will need a long man in the bullpen. If Colby Lewis and Joe Saunders win the two spots in the rotation, Hanson could fill the long-man role.
"With all these starters, somebody will emerge," Washington said. "It's very important, we've got to find somebody down there who can go long."
Hanson followed Saunders, who allowed four runs in three innings while dealing with a blister on the outside of his left foot. Saunders gave up two runs in the first, struck out the side in the second and allowed two more runs in the third. An error by third baseman Adrian Beltre extended the third inning and one of the runs was unearned.
"I kind of felt [the blister] after the first inning but pitched through it," Saunders said. "I had to get my pitches in. It was no big deal. It hurt, but you have to pitch through it."
T.R. Sullivan is a reporter for MLB.com. Read his blog, Postcards from Elysian Fields, and follow him on Twitter @Sullivan_Ranger. This story was not subject to the approval of Major League Baseball or its clubs.


text:
BP Comment Quick Links
|Strength of Schedule Report
June 25, 2012
Value Picks
Second, Short, and Catcher for 6/25/12
Last week, I was hopeful Devin Mesoraco (Yahoo! 3%, ESPN 0%, CBS 23%) was on his way to shaking full blown shared catcher duties with Ryan Hanigan. This week, I'm less confident. In the Reds' last seven games, Mesoraco has started three times, and Hanigan has started four. In his three games started, Mesoraco recorded two hits in nine at-bats with one hit being a double and the other a single. In Hanigan's four starts, he was better, recording four hits in 14 at-bats, adding two walks for good measure. Mesoraco remains a desirable option to own in long-term keeper leagues, but each week that passes in which he fails to impress he looks less desirable to own in redraft leagues. His talent and upside make him watch-list worthy, but beyond that, he shouldn't be owned in most leagues.
My decision to include someone else as this week's AL-only VP has forced Cliff Pennington (Yahoo! 4%, ESPN 2%, CBS 14%) to the departures section. His speed still makes him an ownable option in AL-only leagues, but a 2-for-16 week at the dish gets him the boot in most other leagues.
Owned in more than half of ESPN leagues, we bid adieu to Yunel Escobar (Yahoo! 44%, ESPN 51%, CBS 61%) for the right reason. He didn't light the world on fire last week, but he continues to hit line drives at a high rate while making contact often. Don't let Escobar's season line fool you; he's better than this.
Hanging on by a Thread
Sticking Around
The return of Salvador Perez (Yahoo! 11%, ESPN 7%, CBS 32%) to the Royals lineup provided an immediate boost, as he went 2-for-4 with a dinger in his season debut on Friday. He added another hit on Sunday in four at-bats after sitting out Saturday's contest against the Cardinals. The Royals are nearly certain to give Perez plenty of routine days off, but when he's in the lineup, expect him to perform like a top-flight second catcher in two-backstop leagues.
A timetable has finally been set for Stephen Drew (Yahoo! 22%, ESPN 16%, CBS 42%), and the Diamondbacks are expected to activate him from the disabled list on Wednesday. His usage in the field will largely be determined by how his ankle responds to playing on a day-to-day basis. The team is preparing Willie Bloomquist and John McDonald (both of whom filled in for Drew at shortstop this year) for utility roles, each taking groundballs at third recently. Ryan Roberts has struggled to duplicate last year's breakout campaign and may end up ceding time to Bloomquist and McDonald if Drew proves he's able to play every day. That should alleviate some concern that Bloomquist's passable start to the year may result in Drew sitting more often than he otherwise would. The long and short of it is that Drew is a more talented player than any of the trio of Bloomquist, McDonald, and Roberts, and if he's healthy and playing up to his capabilities, he'll be on the diamond as often as he can handle shortstop duties.
Last Call... For Real This Time
The Angels, as a whole, got off to a slow start, and Erick Aybar (Yahoo! 35%, ESPN 35%, CBS 46%) wasn't spared. Mike Trout is now firmly entrenched as the team's leadoff hitter, meaning that Aybar is slotting in the lower third of the Angels order, primarily hitting eighth. Hitting lower in the order will result in fewer plate appearances for Aybar, but he's squeezing near-maximum value out of them in the last 30 days. In that time span, he's hitting a healthy .305/.353/.442. He understands his game is predicated on speed and has legged out four infield singles while and successfully bunting for a hit seven of eight times in the last month. He won't hit for much power, and last year's 10 home runs look like an outlier, but he should help owners in runs, average, and stolen bases.
Hitting directly in front of the number nine hitter (often a light-hitting catcher) isn't ideal, but being on base when the lineup turns over should prove fruitful for his runs scored totals. He stole 30 bases last year and, most importantly, did so efficiently. This year he has just five stolen bases, but once again, he has been efficient, getting caught stealing only one time. Manager Mike Scioscia is notorious for his propensity to send baserunners. According to The Bill James Handbook 2012, Scioscia ranked fifth amongst American League managers in stolen base attempts in 2011 and seventh in all of Major League Baseball. He may be reluctant to send Aybar with the team's best hitters at the plate, but if he continues to be efficient, there is no reason to believe he won't net 20-25 stolen bases by year's end. Aybar isn't good enough to start at shortstop in mixed leagues, but he's a fine middle infield option and an AL-only shortstop option.
AL-only VP
Unlike some catchers, Norris isn't a slug. He stole 13 bases last year and was up to five this season before getting the call-up. Sharing catching duties with Suzuki and adjusting to big league pitching limits Norris' value to AL-only leagues for the time being, but his power is enough to put him on the radar. That power was on display on Sunday when he lifted the A's to a win over the interleague rival Giants with a three-run homer off of Santiago Casilla.
NL-only VP
4 comments have been left for this article.
BP Comment Quick Links
Chris Nelson - Rockies .... qualifies at 2B - starting 13 straight games has 3 homers in June so far and hitting over .300.....still young he may be that late blooming RH hitter.
Jun 25, 2012 07:33 AM
Josh Shepardson
BP staff
Nelson might be, but his minor league stat line is more good than great considering his friendly hitting environments. It's very, very early in his big league career, and his minor league splits aren't as dramatic, but he has been much better against southpaws than righties thus far in the majors. In 109 plate appearances against lefties, he is hitting .314/.352/.490. Conversely, in 249 plate appearances against right-handed pitchers in the bigs he's hitting .235/.289/.659. Again, I'll reiterate that that sample is small, but it probably warrants monitoring given the huge gap.
Jun 25, 2012 13:41 PM
Ryan Theriot - Don't know what his ownership is, but he offers a decent average, runs scored from the #2 spot in the order and a decent amount of SB.
Jun 25, 2012 08:19 AM
Josh Shepardson
BP staff
Theriot can contribute a passable average (he hit .270 in 2010, .271 last year, and is hitting .270 this year) with no pop. His runs scored will be contingent on him staying in the number two spot in the order, which is possible. He offers no power, though, and he probably won't end up with more than a mid-teens stolen base total. He's 7-for-10 in stolen bases this year, but was an embarrassingly inefficient 4-for-10 in stolen base attempts. Even when he was stealing 20 or more bases a season, he wasn't the most efficient doing so, and at 32 years old, I don't see that changing. He's rosterable in some leagues, but not much more than that.
Jun 25, 2012 13:47 PM
Not a subscriber? Sign up today!


text:
Cyclophosphamide and Cryoablation in Treating Patients With Advanced or Metastatic Epithelial Cancer
Recruitment status was: Recruiting
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
RATIONALE: Drugs used in chemotherapy, such as cyclophosphamide, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Cryoablation kills cancer cells by freezing them. Giving chemotherapy together with cryoablation may kill more cancer cells.
PURPOSE: This clinical trial is studying how well giving cyclophosphamide together with cryoablation works in treating patients with advanced or metastatic epithelial cancer.
|Drug: cyclophosphamide Other: laboratory biomarker analysis Procedure: biopsy Procedure: cryosurgery
|Study Type:
|Study Design:
|Primary Purpose: Treatment
|Official Title:
|Sequential Administration of Cryoablation and Cyclophosphamide for Advanced Solid Epithelial Cancer
- Safety, in terms of absences of severe adverse events (SAE) and unacceptable toxicity
- Tumor response, according to RECIST criteria
|Estimated Enrollment:
|Study Start Date:
|June 2007
|Estimated Primary Completion Date:
|July 2010 (Final data collection date for primary outcome measure)
- Document radiologic and/or tumor marker response to cryotherapy of tumor lesions followed by cyclophosphamide.
OUTLINE: This is a pilot study.
Patients undergo percutaneous biopsy of the targeted lesion prior to cryoablation. Patients then undergo percutaneous or open cryotherapy of the largest or most accessible lesion on day 0. On day 3, patients receive cyclophosphamide IV over 1 hour.
Tumor markers (if applicable) are assessed at baseline and monthly during study until marker progression.
After completion of study therapy, patients are followed periodically for up to 3 years.
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Diagnosis of epithelial solid tumors of any of the following sites or types:
- Lung (closed to accrual as of 4/2/2009)
- Renal
- Prostate
- Breast (closed to accrual as of 4/2/2009)
- Sarcoma (closed to accrual as of 4/2/2009)
- Colon (closed to accrual as of 4/2/2009)
- Liver(closed to accrual as of 4/2/2009)
- Pancreatic (closed to accrual as of 4/2/2009)
- Bone (closed to accrual as of 4/2/2009)
- Head and neck (closed to accrual as of 4/2/2009)
- Melanoma (closed to accrual as of 4/2/2009)
- Carcinoma of unknown primary (closed to accrual as of 4/2/2009)
- Advanced or metastatic disease
- Ineligible for or unwilling to undergo surgical resection
- Eligible for cryotherapy but not expected to be cured by cryotherapy alone
- ECOG performance status 0-2
- Life expectancy > 3 months
- Creatinine < 2.5 mg/dL
- Platelet count >75,000/mm³
- No known HIV positivity
- No active, uncontrolled infection
- Not pregnant
- Negative pregnancy test
- Women of childbearing potential must practice adequate contraception
- No debilitating medical or psychiatric illness that would preclude giving informed consent or receiving optimal treatment and follow-up
- See Disease Characteristics
Please refer to this study by its ClinicalTrials.gov identifier: NCT00499733
|United States, Maryland
|Brady Urological Institute at Johns Hopkins Hospital
|Baltimore, Maryland, United States, 21205
|Contact: Ronald Rodriguez, MD, PhD 410-614-6662
|Principal Investigator:
|Ronald Rodriguez, MD, PhD
|Brady Urological Institute at Johns Hopkins Hospital
|ClinicalTrials.gov Identifier:
|NCT00499733 History of Changes
|Other Study ID Numbers:
|Study First Received:
|July 10, 2007
|Last Updated:
|February 24, 2011
Keywords provided by National Cancer Institute (NCI):
carcinoma of unknown primary
recurrent carcinoma of unknown primary
stage IIIA non-small cell lung cancer
stage IIIB non-small cell lung cancer
stage IV non-small cell lung cancer
recurrent non-small cell lung cancer
extensive stage small cell lung cancer
recurrent small cell lung cancer
stage III renal cell cancer
stage IV renal cell cancer
recurrent renal cell cancer
stage III prostate cancer
stage IV prostate cancer
recurrent prostate cancer
male breast cancer
recurrent breast cancer
stage IIIA breast cancer
stage IIIB breast cancer
stage IIIC breast cancer
stage IV breast cancer
metastatic osteosarcoma
recurrent osteosarcoma
stage III adult soft tissue sarcoma
stage IV adult soft tissue sarcoma
recurrent adult soft tissue sarcoma
previously treated childhood rhabdomyosarcoma
recurrent childhood rhabdomyosarcoma
metastatic childhood soft tissue sarcoma
recurrent childhood soft tissue sarcoma
Additional relevant MeSH terms:
Immunosuppressive Agents
Immunologic Factors
Physiological Effects of Drugs
Antirheumatic Agents
Antineoplastic Agents, Alkylating
Alkylating Agents
Molecular Mechanisms of Pharmacological Action
Antineoplastic Agents
Myeloablative Agonists
ClinicalTrials.gov processed this record on September 21, 2017


text:
Eagles release DeSean Jackson
Indeed, the Eagles are moving on from DeSean Jackson.
In a two-sentence press release, the club announced Friday it had released Jackson, a Pro Bowl wideout who led them in receiving in 2013.
After careful consideration over this offseason, the Philadelphia Eagles have decided to part ways with DeSean Jackson, the club said Friday. The team informed him of his release today.
The move easily one of the biggest headline-makers of the NFL offseason comes after weeks of trade rumors and public discussion of Jacksons future with the Eagles.


text:
Jinsei Anniversary Hatch!
Posted 19 March 2012 - 01:06 PM ( #1 )
1. To enter you will need 1 or 2 of the following tamas
2.You can use either one or two tamas, as you can log up to two at a time, you do NOT HAVE to connect them if you DO use two (you can still use the matchmaker) it is up to you!
Anyone can join, and I think starting this on the 8th of April 2012, as Easter might be a fun time to start!!!
It can begin between 12-7pm, no matter which timezone your in, start at this time in YOUR country's time, it'll be fun to see the different timezones all over the world!!!!
It'd also be good for you to post pictures but you don't have to if you don't want
C'mon, let's see those work Tamas, being used again!!!!!
Hope as many of you can join as you can!!!!! :kisatchi:
Started19 Mar 2012
Last Post12 Apr 2012
Posted 30 March 2012 - 07:01 AM ( #3 )
Posted 30 March 2012 - 09:35 AM ( #5 )
Posted 01 April 2012 - 08:44 PM ( #6 )
Okayy thanks Eternal Mametchi Fan, and MagicMimitchi!!! I'm going to enter the hatch with my v4.5 but might use my v4 as well
I might enter another as well. Depends if my new v4 or uratama arrive in the mail in time for the hatch.
Posted 08 April 2012 - 07:15 AM ( #7 )
Posted 08 April 2012 - 12:14 PM ( #8 )
- Aliciavz88 likes this
Posted 11 April 2012 - 03:11 AM ( #9 )
Anyhow, Obama's teen stage was a Gourmetchi.
Now he is Tosakatchi with the following skill levels:
Pencil - 42
Sparkle - 35
Flower - 9
Posted 11 April 2012 - 07:48 AM ( #10 )
MagicMimitchi, whut tha heck is THAT Tamagotchi???
Anyhow, Obama's teen stage was a Gourmetchi.
Now he is Tosakatchi with the following skill levels:
Pencil - 42
Sparkle - 35
Flower - 9
That's my Entama Cyoi. (Japanese V4) I got it from Japan.
Sorry I didn't update my hatch the past few days. My other Entama I got in the mail was defective so I was a little depressed.
On April 9th, Akiko left me her baby. I named her Akemi. Her baby form is Memeputchi, toddler is Memepetchi. Both these characters you can also find on the 15th Anniversary iD L.
Sorry if the pictures look different. First one was taken with my normal camera. Second with my phone camera.
Also forgot to mention that I tabbed my Tama up when I got my other one. I wanted the new one to catch up with this one, but I accidentally hit reset instead of download when I repulled the tab, so this hatch is over for me sadly.
Edited by MagicMimitchi, 11 April 2012 - 08:37 AM.


text:
You want to learn about Ubuntu?
It's all here - from Hardy Heron to Feisty Fawn
Ubuntu is the free Linux-based operating system designed with frequent updating in mind.
Released in October 2004, it has evolved into one of the best-known branches of the Debian tree and offers a strong focus on usability and easy installation, whether it be on a laptop, desktop or server machine.
With a development plan stretching forward for several years, Ubuntu is an ideal O/S addition to any desktop machine. With all versions including the latest Ubuntu release 7.04, aka "Feisty Fawn", covered in these texts and our special promotional price of 40 per cent off*, these books will help you to take advantage of Ubuntu.
- The Official Ubuntu Book 2nd Edition
Written by leading Ubuntu community members, this book includes all you need to know to make the most of Ubuntu, whether you're a home user, small business user, server administrator or programmer. Covering installation, configuration, desktop productivity, games, management, support and much more, this book will take you from start to finish.
- Ubuntu for Non-Geeks 2nd Edition
This newbie's guide to Ubuntu puts the spotlight on multimedia enablement and desktop effects and lets readers learn by doing. Using immersion-learning techniques favoured by language courses, step-by-step projects build upon earlier tutorial concepts, stimulating the brain and increasing the reader's understanding.
- Ubuntu Linux Bible
From the basics for newcomers to enterprise management for system administrators, this book is what you need to succeed with Ubuntu. From editing graphics to setting up an NFS server you'll learn it all and more with the expert guidance, tips and techniques.
- Ubuntu Hacks
Ubuntu Hacks is a collection of 100 tips and tools to help new and experienced Linux users install, configure, and customise Ubuntu. With this set of hacks you can get Ubuntu Linux working exactly the way you need it to.
- Hacking Ubuntu: Serious Hacks Mods and Customisations
This down-and-dirty book shows you how to blow away the default system settings and customise Ubuntu however you want. You'll learn how to optimise its appearance, speed, usability, and security and get the low-down on hundreds of hacks such as running Ubuntu from a USB drive, installing it on a Mac, enabling multiple CPUs, and putting scripts in menus and panels.
* Offer correct at time of going to press. Offer covers selected titles only. ®