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18F-CP18 Imaging Studies for Cancer Treatment With Birinapant
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- No Study Results Posted
- Disclaimer
- How to Read a Study Record
- 18F-CP18 is a chemical designed for use in imaging studies. It is attracted to tumor cells that are being killed by cancer treatment. Researchers want to test it in imaging studies for people who are being treated with Birinapant. Birinapant is a drug used to treat advanced ovarian, fallopian tube, or peritoneal cancers. It works kills tumor cells that have not responded to earlier treatment. 18F-CP18 may help to monitor cancer treatments with this drug.
- To test the effectiveness of 18F-CP18 imaging studies during cancer treatment with Birinapant.
- Individuals at least 18 years of age who are taking Birinapant for ovarian, fallopian tube, or peritoneal cancer.
- Participants will have a brief physical exam. They will also answer questions about their medical history and any current medications.
- Participants will receive a dose of 18F-CP18, followed by an imaging study. The study will involve a positron emission tomography/computed tomography (PET/CT) scan. The scan will last 40 minutes.
- There will be two more PET/CT scans 1 hour and 2 hours after taking 18F-CP18. These scans will look at how the tumor cells absorb and process 18F-CP18.
- This is a scanning study only. No treatment will be provided as part of this study.
|Ovarian Neoplasms Ovarian Cancer Fallopian Tube Neoplasms Fallopian Tube Cancer
|Drug: [18F]-CP18 Procedure: PET/ CT
|Phase 2
|Study Type:
|Study Design:
|Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Diagnostic
|Official Title:
|A Pilot Study of [18F]-CP18 PET/CT Imaging in Patients With Relapsed Platinum Resistant or Refractory Epithelial Ovarian Cancer, Primary Peritoneal Cancer or Fallopian Tube Cancer Therapy Receiving Birinapant, a SMAC Mimetic Therapy
- Tumor Uptake [ Time Frame: 2 years ]
|Study Start Date:
|November 30, 2012
|Study Completion Date:
|July 24, 2013
|Primary Completion Date:
|July 24, 2013 (Final data collection date for primary outcome measure)
Drug: [18F]-CP18
Dysregulation of apoptosis is instrumental in forming the malignant phenotype and is associated with resistance to chemotherapeutics and biological therapies. Cleaved Caspase 3 (its activated form) plays a key role in the common apoptotic pathway.
CP18 is an enzyme substrate of caspase 3. The formulation [18F]-CP18 includes PEG vector which facilitates internalization and can be non-invasively imaged using PET. Once cleaved into polar fragments by caspase 3, it become trapped within the cells.
In a phase 2 NCI clinical trial (NCI Protocol (#12C0191) CTEP 9235), Birinapant (TL32711), a SMAC (second mitochondrial derived activator of caspase) mimetic, is being evaluated in patients with relapsed platinum resistant or refractory epithelial ovarian cancer, primary peritoneal cancer or fallopian tube cancer.
PET/CT imaging with [18F]-CP18 may enable the non-invasive, in vivo monitoring of this drugs pro-apoptotic effects. If a measureable effect is shown in this pilot study, further evaluation of [18F]-CP18 PET/CT s potential to monitor apoptosis may be warranted.
Primary Objective:
To determine tumor uptake and retention of [18F]-CP18 before and after treatment with a SMAC mimetic (Birinapant, TL32711), in patients with relapsed platinum resistant or refractory epithelial ovarian cancer, primary peritoneal cancer or fallopian tube cancer.
All subjects must meet the eligibility criteria for the phase 2 study of Birinapant (NCI Protocol (#12C0191) CTEP 9235) and be enrolled in or planning to enroll in parent therapy protocol
All subjects must sign a document of informed consent indicating their understanding of the investigational nature and risks of the study before any protocol related studies are performed.
This is a pilot study to assess the change in [18F]-CP18 PET tumor uptake following treatment with Birinapant, a SMAC mimetic drug, in patients with relapsed platinum resistant or refractory epithelial ovarian cancer, primary peritoneal cancer or fallopian tube cancer. Subjects will undergo at least 3 [18F]-CP18 PET/CT imaging studies,one pre-therapy, one within 48 hours after receiving the initial dose of Birinapant, and a third scan within 48 hours after receiving cycle 2, day 15 dose of Birinapant and prior to the tumor biopsy on the same day. An exploration of the relationship between PET imaging parameters and clinical response and various biomarkers (as determined under the referring protocol) will also be performed. Ten patients will be enrolled on this protocol.
|Ages Eligible for Study:
|18 Years to 99 Years (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Subjects with pathology proven epithelial ovarian cancer, primary peritoneal cancer or fallopian tube cancer that are relapsed or refractory to prior platinum-based standard care systemic regimen, enrolled, or eligible to be enrolled in the Phase 2 NCI protocol treatment using Birinapant (NCI Protocol (#12C0191)CTEP 9235); therefore must meet the inclusion criteria for that study
Ability to provide informed consent. All patients must sign a document of informed consent indicating their understanding of the investigational nature and risks of this study before any protocol related studies are performed.
Known allergy to any of the formulation components of [18F]-CP18.
The subject is pregnant or nursing
Participants for whom enrollment would significantly delay (> 2 weeks) the scheduled standard of care therapy.
Participants with any coexisting medical or psychiatric condition that is likely to interfere with study procedures and/or results are excluded.
Participants with severe claustrophobia not relieved by oral anxiolytic medication or patients weighing >136 kg (weight limit for scanner table).
Other medical conditions deemed by the PI or associates to make the patient ineligible for protocol procedures.
It is likely that all patients in this study will be surgically sterile. If this is not the case, the patient must have a negative serum beta HCG within 24 hour prior to PET/CT or be post-menopausal for greater than or equal to 2 years
Please refer to this study by its ClinicalTrials.gov identifier: NCT01766622
|Principal Investigator:
|Karen A Kurdziel, M.D.
|National Cancer Institute (NCI)
|Responsible Party:
|National Institutes of Health Clinical Center (CC)
|ClinicalTrials.gov Identifier:
|NCT01766622 History of Changes
|Other Study ID Numbers:
|Study First Received:
|January 10, 2013
|Last Updated:
|June 30, 2017
Keywords provided by National Institutes of Health Clinical Center (CC):
Pro-Apoptotic Effects
PET Imaging
Relapsed Platinum Resistant or Refractory Epithelial Ovarian Cancer
Additional relevant MeSH terms:
Ovarian Neoplasms
Fallopian Tube Neoplasms
Endocrine Gland Neoplasms
Neoplasms by Site
Ovarian Diseases
Adnexal Diseases
Genital Diseases, Female
Genital Neoplasms, Female
Urogenital Neoplasms
Endocrine System Diseases
Gonadal Disorders
Fallopian Tube Diseases
ClinicalTrials.gov processed this record on September 21, 2017


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Food stamps to be cut by 5 percent, more cuts possible
BAKERSFIELD, Calif. (KBAK/KBFX) - Thousands of families in Kern County who receive food stamps under the Cal Fresh program will see a 5 percent cut starting Nov. 1. And further reductions are possible.
"This is across the board," said Pam Holiwell, assistant director with the Kern County Department of Human Services.
That means that for a family of three with no income, for example, food stamp benefits would be reduced from $526 a month to $497, a cut of $29, said Holiwell.
The 5 percent cut is the result of a temporary boost from the 2009 American Recovery Act stimulus bill. That temporary boost expires at the end of October.
"It means a lot to me, because it's hard, it's hard what I get, it's not enough for my kids," said Lupe Gonzalez.
The grandmother said she relies on $93 of food stamps a month to help feed her family of four. But, it often happens the food stamps run out before the month does.
"I'm telling you, by the end of the month there's nothing," she said, "rice and beans, whatever we can afford."
Holiwell said there's been an increase in the number of people receiving food stamps. Currently, there are 59,709 families with a total of 144,720 individuals receiving aid from food stamps in Kern County.
It is also possible Congress could cut food stamp benefits even further. The Senate and House are expected to resume debate over a five-year farm bill.
The main sticking point so far is over additional cuts to the food stamp program. While the Senate favors a farm bill that would make minor changes to the program, the Republican-controlled House recently passed a bill that cuts nearly $40 billion from the food stamp program over a 10-year period.
"Of course we would like to avoid any further reduction in food assistance to families in need," said United Way of Kern County executive director Della Hodson. "In the current political environment that may not be possible."

subset: commoncrawl


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SHEPHERDSVILLE - The North Bullitt Lady Eagles scored four times in the top of the seventh inning, but it wasn't enough on Thursday as Bullitt Central pulled out a hard-earned 6-4 victory in a key district clash.
This was the fourth time the game had been scheduled and rescheduled because of bad weather and it took some on-field magic from Bullitt Central to get the game played.
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We were contacted just before the end of last year by longtime PixyBlogger Jeffrey Paul with a proposition to provide an extended trial of PixyBlog for his digital photography students in Great Falls, Montana. We were more than happy to help and have provided his students with a trial account for the duration of their course.
The new semester has just started and the students are now beginning to use PixyBlog. A few have started to upload their photos. We're excited to see how this trial goes and the work produced by the students. Of course, please leave comments. We have some great photographers in our community, and I know that we can all help, learn and improve our photography together.
We've had enquiries before from the colleges, schools and teachers about using PixyBlog for their students, but this is the first ever trial. We would be interested in working with other educational institutions on similar projects, simply contact us if you have a proposal.
News and information about the PixyBlog photo sharing community. Check back regularly for updates, or subscribe to our newsletter or RSS feed.
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Fri, Aug 31, 2012 at 1:10 PM
Shout out to my haters sorry that you couldn't BE me.
Nicki taught me to be proud of who I am. Whatever bitches and haters said about me and my way of thinking. We all must love ourselves. People are scared of ones who are ables to love themselves. So they hate, they spit on their faces. But you know what, if they're so jealous when you're proud...than let them saying shit and fuck them. Because you know you're fucking better.


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Painesville police are searching for a woman who robbed the KeyBank branch at 8 N. State St. in the city on Monday afternoon.
The suspect, described as a heavy-set black woman between 30 and 40 years old, robbed the bank at about 1:30 p.m., police said.
The woman entered the bank, told a teller that she had a weapon and that it was a robbery, police said. She was wearing a hooded black coat, dark pants, dark shoes, a maroon hoodie, tan beanie cap and dark sunglasses. The suspect also had what appeared to be acne scars on both sides of her face.
After being given cash from the drawer, the suspect fled on foot into a blue four-door car driven by a white woman in her 40s, police said.
No weapons were shown during the robbery and no one was injured.
Anyone with information regarding the robbery is asked to call Detective Don Ticel at 440-392-5821 or the Painesville Police Tip Line at 440-392-5839.


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Introducing the Ergonomic Carrier, the new Lenny Lamb fabulous wrap conversion full buckle carrier!
The lovely folks at Lenny Lamb has spent a lot of time developing this specially designed carrier with a system of straps and buckles to provide you with a perfect fit carrier. The number one priority was creating a carrier that held your baby in a safe, secure, and comfortable way while being stylish and comfortable for you - the wearer. All components are made from the highest quality materials available!
- 100% cotton
- 290 gsm (medium to heavy weight)
Measurements for the baby sized carrier (please note measurements may vary by 1cm)
Weight range: 14 pounds to 35 pounds
Panel height: 40cm or 15.75in at middle of panel
Panel width at base: 35cm or 13.78in
Panel width at leg opening: 32cm or 12.6in
Measurements for the toddler sized carrier (please note measurements may vary by 1cm)
Weight range: 20 pounds to 44 pounds or 6kg to 20kg
Panel height: 48cm or 18.9in at the middle of the panel
Panel width at base: 45cm or 17.71in
Panel width at leg opening: 38cm or 14.96in
Why purchase a Lenny Lamb full buckle carrier?
- made of Lenny Lamb woven wraps - highest quality fabrics made of the finest yarn, all yarn and dyes used have the Oko-tekst standard 100 test certificate
- made in Poland
- three point safety buckle prevents accidental opening
- three way adjustable shoulder straps for a perfect fit
- adjustable hood
- contoured panel, soft padded straps and legs out padding for the baby


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Hasbro answers our latest questions...
For a great selection of superhero action figures and collectibles, check out fine sponsors BigBadToyStore.com, Urban-Collector.com, BriansToys.com, ClarkToys.com, ToyWiz.com, VNCToys.com, PastGenerationToys.com, YesAnimation.com, and SuperheroToys.com.
For a great selection of pop culture t-shirts and apparel, check out TShirtGurus.com.
1) Will the Marvel Universe line continue to focus on current events such as Secret Invasion or will there also be some classic interpretations of characters in the mix as well?
2) Will the Wal-Mart Exclusive "Gigantic Battles" sets be an ongoing year-long assortment or will they only be released once a year?Yes, we plan to include classic versions as well as current in the 2010 line and beyond.
3) When will you be announcing which characters Hasbro has chosen to compliment the winners of the Marvel legends 2-pack poll?These sets are planned as Fall launches… they are a great addition to expanding the Marvel Universe.
Information on this will be released in early 2010.


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Searching for Affirmation
There are days when we need affirmation: I'm good enough, smart enough and, doggone it, people like me. Then there are days when you have to question the very last part of that affirmation. If anyone holds or has held Cliffs Natural Resources (CLF), you know what I'm talking about. I picked up CLF along with Walter Energy (WLT) on Feb. 4 with a stop set at $32.90. Not good. Not good at all. I've been stopped out of the trade but, unfortunately, stops aren't much help when you get a large gap lower. So even though my stop was set at $32.90, it was executed at $30.90. The stock comprised 0.75% of the portfolio, so the net resulting drag was around 12 basis points, which is certainly not the end of the world, but the gap lower produced a loss slightly greater than where I wanted to limit my risk.
After reading the earnings report, I have found little to like, especially in the way of management. Wall Street will no doubt question not only CLF's acquisitions going forward, but the huge dividend cut only a year after a huge boost is a huge negative. Plain and simple, it means CLF's management has no vision on the company's cash flow or prospects beyond the immediate future. I don't want to be involved if I can't trust the management. Not only are the technicals broken, but the fundamentals are broken and management is lost. Therefore, it is a loss I must take and move on....173 more words left in this article. To read them, just click below and try Real Money FREE for 14 days.
There's no substitute for a trading floor to get great ideas, so Jim Cramer created a better one at Real Money and blogs there exclusively. We then added legendary hedge fund manager, Doug Kass, with his exclusive Daily Diary and best investing ideas. Staffed with more than 4 dozen investing pros, money managers, journalists and analysts, Real Money Pro gives you a flood of opinions, analysis and actionable trading advice found nowhere else, and allows you to interact directly with each expert.
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Topic: Dad diagnosed with ascites
hey there all
My dad was diagnosed with cc in October. He had a resectable klatskin tumor which was removed on october 31. His recovery was going great until thanksgiving when he started with pain. He was admitted to the James (osu) on December 1 for a " biloma" released on December 5. Readmitted on December 10 and was diagnosed with ascites. He was put on a big dose of lasix , some potassium chloride and his antibiotic was changed then discharged on the 12th. He is suffering with chills, which I understand to be common???? And has some confusion, difficulty concentrating and zero appetite. These chills completely exhaust him. I am concerned for his kidneys and his albumin level. What seems like to have been a miracle story is rapidly spinning out of control and I do not know what to do. Any advise? Thank you in advance!


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NEW YORK — Coach announced that Victor Luis has been appointed president and chief commercial officer. Concurrently, he has joined the board of directors. He will become CEO in January 2014. Lew Frankfort will continue as chairman and CE during this interim period and will then become executive chairman.
Victor Luis has most recently served as president international group, with oversight for all of Coach's businesses outside North America. He has been a member of the company's senior leadership team for the past seven years and has led Coach's successful expansion strategy in Asian markets. In his new role, he will be responsible for all business units, merchandising, licensing, corporate strategy and consumer insights.
Frankfort said, "I'm very pleased with Victor's appointment. He has demonstrated the passion, strategic vision, focus, superb execution and strong values that make an outstanding leader. Through Victor's relentless drive and performance, he has spearheaded our meteoric growth in Asia. Victor has also developed talent and forged collaborative teams across geographies. I am confident in his leadership as we execute Coach's transformation to a global lifestyle brand anchored in accessories and write the next chapter of Coach's growth story."
Luis was appointed to his current position as president coach international group in February 2012 with oversight for all of Coach's retail operations outside of North America. Previously, he served in successively senior roles; starting in 2006 he was president and CEO of Coach Japan, he added responsibility for Coach China in 2008 and became president for Coach Retail International in March 2010.
Prior to joining Coach, Luis was the president and CEO for Baccarat, Inc., running the North American operation of the French luxury brand. Earlier in his career, Luis held marketing and sales positions within the Moët-Hennessy Louis Vuitton (LVMH) Group. He holds a Bachelor of Arts degree from College of the Holy Cross and a Master of Arts degree from University College, Durham University, UK.


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Farmers have long known one of the best ways to increase crop production is to add nutrients to the soil. Development and adoption of concentrated synthetic fertilizers, along with plant breeding, irrigation and other technologies, helped fuel the Green Revolution during the middle of the 20th Century.
However, growing demand for food and biofuels in coming years could challenge our ability to produce enough nitrogen, phosphorus and potassium to support higher yields, according to a new report from the Council for Agricultural Science and Technology (CAST). Efficient use of nutrients, and recovery and recycling of nutrients from farm and non-farm sources will need to continue to improve, say the authors of the report titled "Food, Fuel, and Plant Nutrient Use in the Future."
Key points in the report include:
- With a growing population, dwindling arable land, and an increased demand for biofuels, the world cannot count on an expansion of harvested area to fill the demands.
- Grain production will need to increase by approximately 50 percent during the next four decades. Current U.S. growth rates in cereal yields should meet 2050 demands, but greater yields per unit land area require increases in fertilizer nutrient use, advances in genetics, and improved soil and crop management technologies.
- Per-capita consumption of calories will stabilize during the next 40 years, but the composition of diets will change substantially. Consumption of cereal grains will stabilize, while global consumption of meat and dairy products will increase by more than 30 percent.
- In developed countries, the increase in consumption of animal products over the next 40 years will be a modest 8 percent, but in developing countries it will increase by 70 percent.
- Although cereal consumption among humans will stabilize in developed and developing countries, total cereal consumption will increase substantially due to increased feed use.
- In the United States, removal of nitrogen, phosphorus, and potassium from soils has been increasing, and there is a need for increased fertilizer use and more recovery and recycling from farm and nonfarm systems. Commercial fertilizers are responsible for 40 to 60 percent of current U.S. food production.
- Additional nutrients removed from cropping systems as a result of bioenergy production will intensify the need for more balanced P and K budgets. The Future P and K fertilizer use will need to increase or more nutrients will need to be recovered and recycled.
- If nitrogen use follows the trend of the last 20 years, it will increase 44 percent by 2050. Improved N use efficiency could lessen this increase but likely will not eliminate it.
- Nitrogen-fertilizer production uses N from the air and fossil fuels such as natural gas to create ammonia. The ammonia is then either directly applied or used to manufacture other N fertilizer products. Development of new natural-gas sources and resulting lower gas prices likely will reverse the trend toward higher nitrogen prices.
- Commercial phosphate fertilizers are processed from mined P2O5 rock. The United States currently is second only to China in P2O5 rock production and contributes more than 15 percent of the world's phosphate mining.
- Based on rock value, cost of extraction, and 2009/2010 mine production, the U.S. Geological Survey has estimated U.S. P2O5 reserve life at 53 years. However, those estimates increase if higher phosphate prices make additional mineral resources economically viable.
- Potash (potassium oxide) is also mined from extensive geological deposits. More than one-fourth of the world's K2O production comes from Canada, and nearly half the world's known K2O reserves are located within its borders. World K2O reserve life is estimated at 353 years at 2009/2010 production levels.
- The world supply of raw materials needed for fertilizers should be sufficient to meet anticipated growth in demand. Future P and K needs in the United States will be met to an increasing extent by imported raw materials or final products, whereas future N needs could be met primarily by North American production.
The full report is available free as a download or in print from the CAST website.


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Discussion in 'Miscellaneous' started by Spaceman Spiff, Oct 20, 2010.
I'm not the only one - even God draws dicks...
That is adorable.
perfect text on that imaeg
Holy hell I never realised it was Daniel Craig in that film! But I saw it like...10 years ago? I hardly remember.
Is that a real Simpsons gag or just a clever edit? Either way, it's funny.
Taking inspiration from doubleohfive...
I could be wrong but it looks like Matt Groening signed it so maybe it was just a one-off by him.
AAH! The hair, sideburns, and a mustache!
Think is I still think Eccleston manages to look cool, Daniel Craig does just look silly though...
What's that from, anyway?
The signature is a bit strange, but the scene is from ep. 24x05 Penny-Wiseguys.
A mini-series called Our Friends in the North.
And I, inspired by you, made this!
Also: Is it just me, or is Daniel Craig really channeling 1985 Biff Tannen here?
ha ha, yes he is a bit!!
I was thinking Lion-O, myself.
Separate names with a comma.


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STUDENTS from Accrington Academy have been creating a forest camp in a small area at their school.
The year nine and 10 students have been working with the Prospects Foundation on a fire circle, shelter building, cooking over a fire, making a sign for the camp, using tools, and whittling.
The activities were part of a Forest School programme.
Gemma Tomlinson, nature walks project officer and a qualified forest schools practitioner, said: "The involvement of the students in these activities will help them to develop holistically by learning how to manage risk, explore creativity, increase confidence and improve self awareness, empathy and communication skills.
"With sessions taking place over a longer period of time, children are able to become comfortable with an alternative learning environment, to embrace it and really get the most out of their forest school experience."


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ByKristina Peterson
One big consequence of President Barack Obama's Tuesday night win is that he'll get to choose the next chairman of the Federal Reserve. But when might that actually happen? If history is any guide, not for a while.
Traditionally, presidents have waited until the summer or fall to announce their picks to lead the Fed. Ronald Reagan nominated Alan Greenspan in June 1987. The Bush White House consulted Mr. Greenspan extensively before choosing Ben Bernanke, whom George W. Bush nominated in October 2005. Most recently, Mr. Obama announced that he would re-nominate Mr. Bernanke in August of 2009.
Mr. Obama does have one appointment he could make sooner. Governor Elizabeth Duke's term ended in January, though she may remain in office until her successor is confirmed. Appointed by President Bush, the former banker is the only one of the Fed's seven-member Board of Governors not chosen by Mr. Obama. Ms. Duke has emerged as the Fed's housing market expert and helped broker a compromise that paved the way for the central bank's new bond-buying program this fall.
Meanwhile, Fed officials' regular trips to Capitol Hill may prove slightly less contentious next year. Democrats' control of the Senate makes it less likely the Fed will face one unwelcome change some Republican lawmakers have advocated: opening up the central bank's monetary policy deliberations to auditors. GOP lawmakers who have also pushed to narrow the Fed's dual mandate to focus just on price stability won't have the muscle to pass such a bill in the Senate.
The Fed is tasked with promoting both full employment and stable prices, but some Republicans have worried that inflation could spike if the central bank focuses too much on boosting the jobs market. Fed officials say they are able to balance both goals over the long term.
And the central bank will get to say farewell to its loudest congressional critic, the popular curmudgeon, Rep. Ron Paul (R., Texas), who retires in January. Republican Randy Weber, a two-term state representative, won his spot Tuesday night.
Related: Kristina Peterson has details on Markets Hub.


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I'm thinkng that the Pacer's have something up there sleve.
How many times has a trade leaked out like this Bender to L.A. trade and actually happened?
Anyone remember last year how the reports said Bird wanted Luke Jackson from the draft when all along he wanted Ben Gordon?
And we all know that Donnie Walsh likes to give out suprises.
So I'm thinking they are planning a move on draft day, just not what is being rumor or reported.


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Topic: My Lovely Sister
My sister has been in Hospice care for 3 weeks now, because she was doing some dangerous things at home in her increasingly confused state. Previously, she's improved very quickly on admission to Hospice for Symptom Control, but this time she hasn't; instead she has deteriorated rapidly whilst she's been in. She's deeply distressed and begging to come home, even though my house is woefully inadequate for her needs and I'm at risk of going under completely.
Something she said yesterday triggered a memory in me and I asked today if she's still being given the anti-depressants she's been on for many years. I'm aware I'm clutching at straws but the things she's saying (although they may be a result of medication, cancer or a gazillion other unrelated issues) reminded me strongly of things she said the last time she came of the anti-depressants.
The doctor told me they stopped all oral medication last week (abruptly and without consulting her carer [me], her family or her doctor) because of difficulties she has been having swallowing. The result is that she is in extreme physical and emotional distress at this crucial phase of her palliative care and I am screaming blue murder!!!
They've said they'll reinstate the prescription but that it will take 2 weeks to kick in again. I don't believe that will be the case with my sister, as the last time I got her back on them, she rallied within 48 hours. I know she's dying but she's not dead yet and I do NOT want her to go out crying in despair the way she is now. I can't control her death, or her life until her death, but I can and WILL do everything I can to help her leave peacefully, when her time comes.
I'm so angry ... and upset ... and distressed ... and hopeful ... and (yes) despairing myself ...


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Topic: Symptoms dad is having
As I said in the intro section. My 86 yr. old father has been diagonsed with CC. He has a 4 inch tumor in his bile ducts that is blocking some ducts, but not all. He had an ERCP, but the dr. found that some ducts were draining on their own, & did not insert stents. He has had a follow up with his family dr. on 3/24. He said when he first saw my father on 3/13 his jaundice was around 13, on the 24th, he said it would be more of a 6. Is there a scale for this? He does look better. He spent 6 days in the hospital & is home now. He was weak & using a walker for the first few days & then for about 9 days, he had been walking fine & regaining his strength. The last couple of days, he is weak again & having symptoms of a urinary track infection, or possibly an enlarged prostate. Also, constipation. We are encouraging him to eat, but he says things just don't taste. He is eating small amounts & whe he went to the family dr. he weighed the same as when he went into the hospital, so he didn't loose any in there. I try to get him to drink plenty of water, but he doesn't. He does like the flavored waters I've been getting him. He is drinking juices & popsicles. My dad was never really a "sweets" person & now, he wants sweets all day long. He's eating candy, baked goods, etc. My next concern is his blood sugar level. He has not been in any pain or had to take any pain meds since the first day in the hospital, so that was 3/14. I think that's good that he hasn't needed any. I do have a ? about the spreading of this disease. The GI specialist told us it wouldn't spread, that it would just grow in his liver, making him more uncomfortable with eating & he would gradually stop eating. Tomorrow he sees a GI specialist that is in the same practice as the one at the hospital. I'm wondering if this is really a "2nd opinion", as it is in the same practice. We don't see an oncologist until 4/15. My dad was diagnosed with prostate cancer in 1995, but at the time, the urologist told him it was so slow growing, to basically not worry about it. In the CT scan before he went into the hospital it said his prostate gland had "dystrophic calcifications". Is that cancer? I'm sorry this is so long, but I wanted to give a little update & also ask anyone here what ?? I should be asking the dr. tomorrow. My dad wants to ask about an appetite stimulating drug. Thanks!


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Welcome folks to this week's edition of Big Redfish R Us.
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Results 1 to 4 of 4
Thread: Birdboy!
June 19th, 2013 09:12 PM #1Member
- Join Date
- Mar 2013
- Posts
- 86
All right, so this isn't so much of an actual story as it is a series of drawings with explanations or short comics to help me practice my artistic skills (which need refining!). Basically, my main character is a little boy aged between 5 and 8. He's a pretty cute little guy, with biiiiiig blue-grey eyes and a mop of wavy/curly medium-dark golden hair. He has a big grin and just likes to have fun all the time. I affectionately call him "Birdboy" because that's what he is- part bird, part adorable little boy. He can turn into a bird (specifically an American Goldfinch!) in any amount, from fully becoming the animal to just sprouting wings out of his back/changing his arms to wings. His last name is Spinett (a little play on the Latin name of the American Goldfinch, Spinus tristis). It's the first name I'm struggling with- I can't decide between Abraham, Gideon, and Carey. If anyone has any opinions or other suggestions, all help is welcome and needed!! Thanks!
June 19th, 2013 09:29 PM #3
June 19th, 2013 09:55 PM #5teenberry -- writer -- drama kidCurrent crushes (constantly changing):Girls: Thea, Aurelia, Rosalind, Rose, Rowena, Helena, Hermione, Carys, Clio, Cassia, Viola, Lily, Lila, Lucy, Seren, Maia, Mirabel.Boys: Miles, James, Jasper, Jude, Graham, Arthur, Oliver, Leo, Lewis, Wesley, Rory, Rowan, Caspian, Silas, Sebastian.
June 20th, 2013 02:29 AM #7Member
- Join Date
- Mar 2013
- Posts
- 86
It was ALMOST Gideon for him, but then all of the sudden, an image of a little ginger boy who could turn into a bear popped into my head and he made the absolute perfect Gideon-- I couldn't resist. So Birdboy became Carey! There's also Bean, who's a little girl who can become a starling. Thank you so much for your input though! He definitely would've been Gideon had the ginger boy not come to mind.


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JVC's KD HDR1 is one of the few in-car stereos on the market that comes with a built-in HD (hybrid digital) radio tuner. HD radio works by sending out a traditional analog signal as well as digital signal, which can be used to transmit text data such as song and artist details. Radios with a built-in HD receiver sort through the multiple signals and reproduce the original broadcast without the multipath distortion associated with standard analog FM and AM reception. The KD HDR1 can also play MP3 and WMA discs and can be connected to iPods and satellite radio via add-on modules.
Like other products from JVC's KD range we've seen, the single-DIN-size KD HDR1 features a well-designed control interface with a good combination of buttons and dials for selecting and tweaking audio sources. On the left of the KD HDR1's faceplate, a backlit D pad provides the means of skipping tracks and folders (for disc-based audio) and radio channels (including multicast programs on HD radio); it also acts as a proxy control interface for iPods, which are connected via an optional module.
A volume dial and a standard row of hard buttons along the bottom of the system's single-line monochrome display rounds out the picture. While we are not crazy about the size of the display and the fact that it is limited to showing eight characters at a time, it is bright enough to be visible from the driver's seat, even in direct sunlight.
Features and performance
The KD HDR1's headlining feature is its built-in HD radio receiver. Comparing the sound quality of HD- and standard- analog broadcast on the KD HDR1 is easy, as it takes up to 10 seconds for the device to pick up the radio channel's HD signal after it has found the regular analog signal. During the time it takes to lock onto the digital signal, an HD icon flashes in the bottom right-hand corner of the display. The difference between the two signals is startling: when the HD mode kicks in, the audio output becomes far clearer, with the hissing and fuzz associated with regular FM broadcasts completely eliminated. In HD mode, the KD HDR1 reproduces instruments and voices with greater clarity, and acoustic separation is far more distinct than in analog mode.
Another benefit of HD radio (other than its being free) is its ability to carry multiple channels of music from the same radio station--so-called "multicasts." Most HD stations have only one or two channels on each channel to date, but there is potential for up to seven channels to be multicast on a single FM or AM frequency.
For disc-based media, the KD HDR1 plays CDs and homemade MP3 and WMA discs. If the latter are encoded with ID3 tag information, that can be called up on the stereo's monochrome LCD faceplate. Only eight characters of any one tag (artist/ track/ album etc) can be displayed at once, though tags can be set to scroll via an option in the Select menu.


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'The big topic at Wednesday practice was the proposed rule changes by the NHL's general managers. Lindy Ruff and Miroslav Satan both like the rule giving goaltenders a two minute penalty for going behind the net. Both feel it will lead to more forechecking which leads to more scoring opportunities. Defenseman Alexei Zhitnik isn't as enthusiastic. He claims forwards will be in on the "D" quickly causing more violent collisions into the wall and more injuries. Mika Noronen says he'd miss handling the puck, but he'd live with it.'
You are here: Home / SabresBeat / Sabre Players Intrigued By Rule Change Proposals


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Stewart running out of time to prep for season
LAS VEGAS -- Ian Stewart is running out of time to get ready for the regular season.
The third baseman will undergo another MRI on his left quad because of lingering soreness that has kept him from running the bases and out of games. Stewart injured his leg during an intrasquad game on Feb. 21 and did not play again until March 14, in a Minor League game. He has been unable to get into another game since.
Manager Dale Sveum said Stewart told the athletic trainers that the latest problem isn't a setback. However, the reality is that the Cubs have two weeks remaining before Opening Day, April 1.
"I don't know if he's got enough time," Sveum said. "It'll be interesting."
Stewart was limited to 55 games last season before of a sore wrist, an injury that needed surgery, though that hasn't been a problem this spring.
Whether Stewart is ready for April 1 will affect how the Cubs put together their bench. Brent Lillibridge and Luis Valbuena can play third, as can Edwin Maysonet and Alberto Gonzalez.
"It just comes down to, what do you want in that spot?" Sveum said. "[Steve] Clevenger's obviously a guy who could be interesting, [and we're watching] all the waiver wires."
Clevenger made the Cubs' Opening Day roster last year as the backup catcher but on Saturday played first and third. He could be an emergency third baseman, plus give Sveum more options with double switches.
Others in the mix for the bench spots are non-roster invitees Darnell McDonald, Brian Bogusevic and Dave Sappelt, all outfielders.
"It all depends, when we sit down and really hardcore look at it, what is our need, how does the pitching set up with the other team, who's their closer, set-up guys, left-handed guys," Sveum said.
Carrie Muskat is a reporter for MLB.com. She writes a blog, Muskat Ramblings, and you can follow her on Twitter @CarrieMuskat. This story was not subject to the approval of Major League Baseball or its clubs.


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Offense comes alive for Mariners in Cleveland
Seattle, which struggled to score at home, posts four-run fourth
CLEVELAND -- A Mariners team that has proven it has the pitching to stay in the American League playoff chase showed once again what it can do with a little offense to go with that as Seattle topped the Indians, 5-2, to open a six-game road trip on Tuesday at Progressive Field.
The Mariners' record is now 39-10 when they score four or more runs, though the challenge has been to reach that benchmark consistently enough to take advantage of the lowest ERA in the AL.
"We definitely have a lineup that can produce runs, one way or the other, whether it's playing small ball or having a couple big hits here or there," catcher Mike Zunino said after helping the cause with a home run and a double. "I think we're turning a corner. We know the pitching staff and bullpen is going to be there. If we find a way to score those three-to-four runs, we're feeling pretty good."
Hisashi Iwakuma was the beneficiary of Seattle's highest-scoring output in its last seven games as the right-hander threw seven innings of two-run ball to elevate his record to 9-5 with a 3.06 ERA.
"I was very happy for that four-run inning [in the fourth]," Iwakuma said through translator Antony Suzuki. "The last couple starts I'd give up the first run, give up the lead early, and today I didn't want to do that. Those four runs helped."
The Mariners snapped a six-game losing streak at Progressive Field, where they hadn't won since 2011, as they improved to 55-51. After going 2-5 and scoring just 15 runs in their just-completed homestand, the win got the Mariners off on the right foot on their trek to Cleveland and Baltimore and kept them within two games of Toronto in the chase for the AL's second Wild Card berth.
Though the club is still just 4-7 since the All-Star break, manager Lloyd McClendon said that record is a bit misleading given five of the losses have been by one run.
"You don't win those and you don't look good and people say you're playing bad, and that's just not the truth," McClendon said. "One hit in [those] five games and we'd have a pretty nice record coming out of the break, but it is what it is. We had a nice night tonight. Guys came out and put some good at-bats together and hopefully this can jumpstart us."
Zunino ripped his 16th home run of the season and the Mariners added a triple and five doubles in a game where they knocked Indians right-hander Trevor Bauer out after 4 1/3 innings. The seven extra-base hits were one shy of Seattle's season high.
Zunino went 2-for-3 with one of the doubles and also was hit by a pitch while moving into a share of the Mariners' lead for home runs with Kyle Seager with his fifth-inning blast. The 23-year-old leads all AL catchers in homers and is three shy of Seattle's club record of 19 by Miguel Olivo in 2011.
The Mariners' four-run fourth was helped by a two-run double by Dustin Ackley and RBI doubles by Corey Hart and rookie shortstop Chris Taylor. Seager got the rally started by dropping a bunt single down the third-base line against the Indians' shift, then added a triple in the seventh as his 2-for-5 night puts his career average at .417 in 11 games at Progressive Field.
"Today was definitely a better feeling as far as getting ahead and keeping that lead," Ackley said. "When we get ahead of these teams and they know Iwakuma is on the mound and our bullpen has been pretty unstoppable, that puts pressure on them. That's a good position for us to be in."
Ackley, hitting leadoff for the first time this season, went 3-for-5 with a double and two RBIs and is batting .390 in July to lift his season average to .256. Hart's double was just his third extra-base hit -- all two-baggers -- and third RBI in 19 games since coming off the disabled list on July 4.
Iwakuma saw his streak of innings without a walk end at 35 2/3 when he threw four straight balls to Michael Brantley, the third batter in the first inning. Iwakuma faced 139 batters -- with 34 strikeouts -- since the last walk he issued on June 25 against the Red Sox.
But Iwakuma breezed through seven innings with just one blip, allowing a pair of runs and three of his six hits in the fifth. The 33-year-old Japanese standout hasn't lost on the road since July 4, 2013, going 9-0 with a 2.17 ERA in that 14-game span.
"To be honest, I didn't even know about that," Iwakuma said when asked about his run of road success. "I don't know what the secret is."
Whatever it is, the Mariners seem to be sharing it as a team. Seattle is now 29-20 on the road this season and 26-31 at Safeco Field.
Fernando Rodney finished things off in the ninth for his AL-leading 29th save as the Mariners changed some of their recent history at Progressive Field, which hasn't been a friendly road venue. Of Seattle's six straight losses in Cleveland, four had come on walk-off hits on blown saves by different Mariners closers.
Greg Johns is a reporter for MLB.com. Follow him on Twitter @GregJohnsMLB as well as his Mariners Musings blog. This story was not subject to the approval of Major League Baseball or its clubs.


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according to Stein:
New Jersey has the worst record in the league against the 14 teams in the NBA with a winning record as of Friday morning. During the regular season, such statistics don't mean everything, but the numbers below aren't especially encouraging:
WORST vs. TOP 14 W-L; Pct. New Jersey; 8-16; .333 Milwaukee; 9-15; .375 Houston 10-16; .385 Portland; 11-15; .423 New Orleans; 11-14; .440
BEST vs. TOP 14 W-L; Pct. Minnesota; 19-9; .679 Dallas; 21-11; .656 Sacramento; 17-10; .630 Indiana; 14-10; .583 San Antonio; 15-14; .517
P.S. If it makes the Nets feel any better, since Dec. 4, the Lakers are 3-11 against teams with winning records.
glad someone who gets paid says what I've been saying for weeks, wonder where my paycheck is


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It's difficult (if not impossible!) to pick only one paleta flavor at La Newyorkina...but now...problem solved! Meet the Rainbow Paleta ($4.50 at the Big Gay Ice Cream Shop), where not one but four flavors comes layered into a single popsicle. The flavors change often, making a solid case for visiting as frequently as possible. Today we devoured a shiny compilation of summer berries (at the top) layered with pineapple, coconut, and green apple at the very bottom. As always, the layers are true to flavor and never too sweet. I'm crossing my fingers that passion fruit shows up in the next quartet of flavors.
La Newyorkina at the Big Gay Ice Cream Shop
125 East 7th Street New York, NY 10009 (map)
Follow La Newyorkina on Twitter for additional locations
About the author: Originally from Honolulu, Kathy YL Chan blogs at Kathy YL Chan, where she chronicles her eats and travel adventures between Hawai'i, New York and beyond. She firmly believes that there is always room for dessert.


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Thank you for your post on Ajahn Maha Bua. That was very nice to read. A comment and a question...
Dhammanando wrote:I don't personally know of any Thai monastery of which I could say: "All (or most) of the monks living there both observe the Vinaya well and avoid the extremes of eternalism and annihilationism." One can say this of individual bhikkhus, but one can't say that such a thing prevails in any community that I know of.
Nor even in the Buddha's day with the Buddha as a teacher no less!
For this reason, I think it's desirable that a monk in his formative years should gain experience in both urban pariyatti and forest kammaṭṭhāna wats, taking what's best from both of them and then, when's he's got ten rains under his belt, getting the hell away from them.
And where would you suggest he go from there?


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Click here for a complete list of Luke Bryan tickets including later concerts.
Tickets Cheapest Latest News as of September 26, 2017
Read all the up to date information on concert news, specials, hot deals and other happenings on the Tickets Cheapest website.
Luke Bryan Chula Vista, CA Concert Releases Tickets, With Seats Still Available at LukeBryanConcerts.com Online Including Cincinnati Concerts Saturday And Sunday
Luke Bryan concert tickets for an October 24 show in Chula Vista, CA at the Sleep Train Amphitheater go on sale to the public to buy today. Fans may also buy all other Luke Bryan tickets at Financial Firebird Corporation's LukeBryanConcerts.com or Tickets-Cheapest.com where they will pay less than at other resale sites after the box office sells out for a range of seats from cheap areas to premium seats or a lawn ticket.
- Read Full Article 08/22/2014
- Get Tickets Now!


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Florida's gambling options expand as regulators shift policy under Scott
Days after a judge ruled last month that the barrel races held at a fledgling North Florida racino were not a legitimate parimutuel sport, state regulators crafted a license, the first of its kind, to allow "flag-drop" races to replace them.
In the past two years, the same regulators have allowed slot machine operators to run electronic roulette and craps games in Miami-Dade and Broward counties, allowed a dormant jai alai permit to be used to expand the number of slot machines at Magic City Casino, and allowed Tampa Bay Downs and Gulfstream racetrack in Hallandale Beach to run a one-time race in June so they could offer thoroughbred races via simulcast year-round.
These are just a handful of decisions by state regulators that have effectively expanded the gambling footprint in Florida under Gov. Rick Scott.
"There are a couple of clever lawyers out there and we're seeing a lot of strange decisions,'' Kent Stirling, executive director of the Florida Horsemen's Benevolent and Protective Association, told the Times/Herald. "If the law doesn't specifically say no, the answer from the department seems to be, always, yes." …Full Story


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Electronic BallastLike
galen hsia
Contact Manufacturer
galen hsia
Sinobase Tech-Industrial Co., Ltd.
Product Range Main products
LED Driver,CFL, T5/T8/TC Ballast, Transformer, etcTarget Market(s)
Hong Kong/ Macao/ Taiwan; Latin America; Mainland China; Western & Southern Europe; Northern Europe; Central & Southern Asia; Middle East
- Product Details
- Company Profile
Basic Specification
|Start Mode
|Quick Start
|Fluorescent Lamp
|Fluorescent Lamp
Detail Description
Additional Information
|Payment Terms
|L/C, T/T, Others
|Minimum Order
|100 pcs
|Lead Time Delivery Time
|30 days
|Sample Available
|Yes Ask For Sample
|Target Market(s)
|Africa(except Middle East), Central & Southern Asia, Eastern Europe, Latin America, Mainland China, Middle East, North America, Northern Europe, Southeast Asia, Western & Southern Europe
About Us
Sinobase Tech-Industrial Co., Ltd.
In this enlightened age we are committed to bringing you light wherever you are.SINOBASE is a unique company who has been delighting global majors for over seven years with a complete turnkey service specializing in the design and manufacturing of professional lighting products. Our portfolio includes ballasts, energy saving lamps, and PCBs.Our expertise and dedicated staff will make us your first choice as an outsourcing partner, general contractor or complete solution provider.The SINOBASE team of professional design and production Engineers are always ready to provide you with new products whose guaranteed quality is supported by well equipped laboratories for electronic and photometric measurements.SINOBASE has factory facilities in Ningbo, Yangzhou, and Nanjing. The production lines use the latest automation techniques from around the world. RoHS compliant process capabilities include automatic PCB population, SMT, vacuum deposition, injection moulding, die-casting, and tool design.We have an in-depth knowledge of the domestic component market allowing us to provide the most cost effective solution for your products by expertly matching the part to the design life. We can do this not only for electronic components but also for plastics piece parts, moulds, and production tooling.
General Information
|Year of Establishment
|US$10 Million - US$50 Million
|Sales Volume
|US$10 Million - US$50 Million
|Brand Name
Export Information
|Export Year
|Export Percentage
|91% - 100%
|Delivery Time
|15 days
|Minimum Order Quantity
|Payment Terms
|L/C T/T Others
Productivity Information
|Production Lines
|5 lines
|Factory Size
|1,900 square meters square meters
|Monthly Capacity
|Investment on Manufacturing Equipments
|US$2.5 Million - US$5 Million
|No. of Staffs
|101 - 500 People
|No. of R/D Staffs
|11 - 20 People
|No. of Engineers
|5 - 10 People
|No. of QC Staffs
|11 - 20 People
Factory Info: Nanjing Sinobase Tech-Industrial Co., Ltd.
Nanjing Sinobase Tech-Industrial Co., Ltd.
|Nanjing, Jiangsu, China
|No.738,Dixiu Road,Binjiang Economic Development Zone, Jiangning, Nanjing
|Factory Introduction
|Sinobase Tech-Industrial Co., Ltd was established in 2002, and we set up two secondary self-own plants: Ningbo Sinobase Electronic-Industrial Co., Ltd and Nanjing Sinobase Electronic-Industrial Co., Ltd. The former Ningbo Sinobase Electronic-Industrial Co., Ltd was the subsidiary company of one listed company, and it was taken over by Sinobase Tech-Industrial Co., Ltd later. Nanjing Sinobase Electronic-Industrial Co., Ltd was established in 2005, with the registered capital of USD $5 million. Our company started to run officially in August, 2006, and it is located in beautiful Ningbing Technology Development Zone, Jiangning, Nanjing with excellent geographical environment and convenient transportation. Professional, creditable, service and quality are our development philosophy. We are specializing in the processing manufacture and exportation of energy saving lamp and ballast, and we have a excellent team for development and technology research, basing on the guarantee in terms of R&D technology, our products are appraised by customers. So far, our customer groups are mainly from European and Western Asian markets. We have established good business cooperation with famous energy saving lamp plants in European and Western Asian local areas, and we have taken up certain market share in the local consuming area. For recent years, as a constant developing enterprise, our exportation and importation business is outstanding. We will plan to devote ourselves to the constant development of the South African markets for the future.


text: First and foremost I would like to thank Brian (Powershift03) for his help with getting me in touch with John. I could have never had the opportunity without him. I have been working on Mustangs for 20 years and never had my car in a magazine. I have only had other peoples cars that I have worked on in them. Now thanks to Brian and John I was able to! Anyway, here it is!!!! Here is the cover: Article:


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Smile ... Life Is Three Cushion Mug
Product Color:
Product information
Your own personalized Mug Smile ... Life Is Three Cushion ensure that your morning coffee, or tee, or chocolate milk, tastes better. The ceramic ensure long durability and give your morning breakfast a sophisticated air, which will also keep your beverage hot longer.
No one can ruin your day after sipping from your favorite Smile ... Life Is Three Cushion mug. And if you aren't a morning person, our 11oz Three-Cushion
Sku: TZ0WH0000004880202020606BNDS00000


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BOULDER CREEK >> Firefighters contained a 3.2-acre wildfire that broke out Wednesday morning in Big Basin State Park.
No one was injured and no buildings were damaged in the blaze, which started about 6 a.m. and was contained about 10:30 a.m., said Cal Fire Capt. Ron Michaelsen.
Also Wednesday, dry conditions across the state prompted Cal Fire leaders to issue a backyard burn ban across 31 million acres of Cal Fire covered areas. A ban on brush burning at homes in Santa Cruz County already is in effect.
"The increase in fire activity this year, coupled with record-setting drought conditions, requires us to take every step possible to prevent new wildfires from starting," said Cal Fire Director Ken Pimlott.
Firefighters are investigating what started Wednesday's fire in Big Basin State Park.
About 6 a.m., several people reported a fire near the Blooms Creek Campground in the park near Highway 236 and Sky Meadow Road, said Michaelsen.
A Cal Fire helicopter dropped water on the blaze and two Cal Fire planes dropped fire retardant. Fire crews on the ground surrounded it with a hose line and fought it with water, firefighters said.
Temperatures were in the 60s with about 45 percent humidity and 2 mph wind, authorities said, so crews did not encounter adverse weather to whip up the fire. However, Michaelsen said, redwoods and dense piles of dry leaves on the ground made it difficult to fight.
Wednesday afternoon, crews continued to stamp out hot spots in the area, Michaelsen said. They planned to be there through the day.
"Even though it's a relatively small fire acre wise, it requires a lot of resources to actually finish it up," said Michaelsen.
Authorities were not sure if all the burned wildland was inside Big Basin State Park. Firefighters from Boulder Creek and Bonny Doon also responded.
Throughout the spring, firefighters have warned residents in Santa Cruz County and throughout the state about dry conditions because of the drought.
Cal Fire already has responded to 2,118 fires in 2014, a nearly 70 percent increase from recent years.
Campfires at some campgrounds still may be legal, but authorities advised campers to check with rangers and visit the park's website for more information.
Rural Santa Cruz County residents have been asked to create 100 feet of defensible space around their homes and 30 feet of "lean vegetation" near it. Residents also are advised to plan exit routes in case of wildfire and keep a checklist of essential items to pack.
To see tips from the state's wildfire preparedness website, visit www.ReadyForWildfire.org.


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A DOVERCOURT beach could be closed to the public after two wartime hand grenades were discovered at the weekend.
Officers from Tendring Council's Seafront and Parking team carried out a search of the beach on Monday morning following the discoveries on Saturday and Sunday.
Temporary signs were also put up to inform all beach users of the situation and warning them of the potential danger.
They will be replaced with more permanent signs.
The council is now seeking expert advice on the best way forward, which may include closing off the beach.
Nick Turner, cabinet member for environment and coast protection, said: "We now need to move in and decide what measures we need to take to ensure the safety of all those who use the beaches.
"Immediate action involved carrying out a careful search of the area yesterday and then putting up warning signs.
"At the same time we are gathering advice to work out if we need to go further. Although we do not want to close beaches to the public in the summer we will not hesitate to do so if that is the advice we are given."
In July three other wartime grenades were discovered and blown up by bomb disposal experts.


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Thanks for those posts about the workaround. However, this issue is not about Chinese gibberish appearing in distributed versions of the program; it is about the original source code getting corrupted. Cheers, Halden
Dear All
I want to add that my Distributed Systems Manager turned Chinese after upgrading from I believe cFP 6.0.6 to cFP 6.0.7 or was it 6.0.8. I therefore conclude that this problem is not just related to LV 2010 upgrade nor to the SP 1. Perhaps a small clue is that the Fieldpoint driver seems to use the folder
C:\National Instruments Dowloads\FieldPoint
(please notice the misprint 'Dowloads' and not 'Downloads')
Jon S. wrote:
2nd Issue:
This is the issue that falkpl reported. Sometimes after a LabVIEW crash or building an application the internal Unicode flag gets turned on for many of the LabVIEW objects. This case we have been unable to reproduce after vigorosly attempting to do so. We are working on implementing a fix that would help the user out after this happens but as of right now we haven't determined what exactly causes this bug. This CAR has been reported as 185890. If you expereince this behavior contact NI support. We will try to help recover your VIs as much as possible.
Hello Everyone,
I believe that we have a better fix for VIs that have become corrupted because of CAR 185890. If you experience this behavior contact ni.com/support and ask the Applications Engineering to search for KB 4Z7BPBUB. This is an internal KB that I just updated with the new information to hopefully recover VIs in this condition. I didn't have a large sample set to test but the sample VIs I had were successfully saved. Our previous recovery tool only fixed the front panel objects but this fix should recover everything.
We still cannot reproduce what caused the VIs to get into this state so if you can reproduce this behavior please let us know. Thanks for everyone that helped give us information to try and fix this bug.
Why not simply make the tool available publicly somewhere?
We also had a massive "chinese corruption" in hundreds of VI's after a mass compile / build. The front panels and block diagrams are permanently corrupted for us. It's not just the built app.
It's weird though, half the strings are in chinese, and the other half are fine...
Dear NI,
Please present a solution to this "language" problem. I ran a support case on this only to be answered "our computer does not give this problem". All I want and need is a solution.
søren hallberg jensen wrote:
Dear NI,
Please present a solution to this "language" problem. I ran a support case on this only to be answered "our computer does not give this problem". All I want and need is a solution.
Hello Søren,
As of right now we do have a solution to both of the problems described in this discussion forum.
If you have problem described in CAR 202900, please see this post.
If you have the problem described in CAR 189850 see my post above.
To answer Dinçer's question, the utility we have created isn't in a position to be publicly facaing at this time. We are working on make a solution publicly available though. In the time being please contact NI support if you need help with either of these situations.
But if I was to contact NI, is it a tool that the support guy would send me, or would I need to send him my VI's? For confidentiality and practicality (hundreds of VI's involved), having to send the VI's wouldn't work for us.
I ask this out of curiosity more than anything else, since we simply rolled back to a few days ago to "fix" it. But if the issue reappears, it would be good to know.
Anyways, it's good to hear you guys are working on something
I have this problem right now.
Tried to create the VI as suggested by an earlier poster, but cannot find the Unicode property. Code is attached
Hello nrp
You may wish to create a new forum post for this issue so that it receives the proper attention. Can you please describe your situation and application in a bit for detail for me as well as provide me with the version of LabVIEW you are using and which operating system your PC is running? Can you please reference the previous post that this refers to? Thank you very much!


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With a Great Heel comes Great Responsibility!!!!Daniel Bryan is without a doubt the greatest talent WWE has currently, he is by far the most "over" on the entire roster and don't tell me that when he walks through the curtain you don't through your hands in the air and chant "yes,yes,YES!" just like everyone else.
While Daniel is awesome no doubt, he is nothing without his great heels
Do you sit by your tv on Monday nights and wonder what the hell is the WWE thinking with their programming? Of course you do! After reading so many dirtsheets and listen to the IWC rant about how they hate the WWE right now. Hate the direction of the company. Hate that PG rating that stole away their precious Attitude Era. It can only be attributed to a few things. So here they are.
Updated 02-10-2014 at 12:43 PM by Megatron
It's the night after Wrestlemania 30, Monday Night Raw , The Authority stands in the ring with their newly crowned , newly turned heel Batista. Brock Lesnar stands beside him with Paul Heyman after a unbelievably shocking defeat of the Undertaker, doing the impossible and ending the streak. John Cena stands beside them after decimating the Wyatts single-handedly. Kane, Brad Maddox and a few others
© 2011 eWrestlingNews, All Rights Reserved.


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WATCH: Denon AVR-X2000 unboxing video
Exciting times for us, as we're getting our hands on the first AV receivers for 2013: stepping up now is the Denon AVR-X2000. Denon hopes its new X-series of amps will have the X-factor that, if we're being harsh judges, hasn't quite been there for a few years. The AVR-X2000 is right on the £500 price sweet spot, and takes the place of the four-star Denon AVR-2113 from the 2012 range.The AVR-X2000 is a 7.1-channel amplifier – so you get just the one subwoofer connection. All the speaker terminals, including those for an optional second zone, have banana plug-compatible terminals and are neatly laid out on a surprisingly clean-looking rear panel.
The X2000 delivers 95W per channel of power in to 8 ohms, and, of course, supports the full range of now typical digital sound processing – including Dolby TrueHD, DTS-HD Master Audio and Dolby Digital IIz (the latter for adding front height channels to create a 9.1-channel speaker set-up).
You shouldn't be short of HDMI inputs (there are seven here in total, with one on the front of the receiver), and future-proofing is covered in the X2000's 3D and 4K compatibility.
There's 4K upscaling of digital and analogue video sources, and there's an ARC (Audio Return Channel) on the single HDMI output, too. Twin HDMI outputs on AV receivers are becoming more common (they let you run two displays, such as a TV and a projector) though this probably isn't an issue for most users – so we won't grumble too much here.
Network connectivity
On the subject of wireless, there is support for Apple AirPlay, bringing wireless streaming from iPhone, iPad, iPod Touch and iTunes on computers, and DLNA 1.5, which means support for streaming DLNA-certified devices, including 24-bit/192kHz hi-res WAV HD and FLAC HD audio files. There's no sign of Bluetooth, though, which is a stand-out feature of Onkyo's 2013 AV receivers, such as the £500 TX-NR626.
Connect the Denon AVR-X2000 to your home network and you can also access a range of streaming services. Spotify and Last.fm, increasingly common on home cinema devices, are present and correct here, as is the apparent internet radio app of choice, vTuner. Flickr photo streaming is supported, too.
More after the break
Like the receiver's front and back panels, the AVR-X2000's new interface looks clean and clear, with a simple series of main menus that leads you to all the key modes and features. In our listening rooms we opt to turn off the room-correction and EQ options, which seem to be on as standard, and sit back to enjoy the action.
The Last Stand, Arnold Schwarzenegger's return to Hollywood blockbuster action, is a good test of sound (and vision) – and immediately the Denon has our attention. We like to play our movies loud, but the level of excitement and engagement mustered by this new X-series amp is immediately impressive.
Sound quality
In no time we're happy with the more upbeat delivery we're enjoying. At the bottom end there's no issue with soft bass notes slowing the pace – the low frequency performance, whether as part of explosive action or when it comes to soundtracks and music – is tight and agile, punchy and expressive.
At the high end of the frequency range, where a silky-smooth delivery is more welcome, the AVR-X2000 does occasionally sound a touch bright when played at high volume, but at moderate levels it isn't an issue. Dialogue otherwise is clean and expressive, intonations in character's voices (Arnie's perhaps less so…) are apparent where they might not be on rival amps.
This Denon is simply revealing more. The Skyfall soundstage is big and brimming with insight, with every shuffling foot, every morsel of debris, apparent in our listening room. Effects fly around with seemingly effortless ease, too – the X2000 is adept at steering effects from speaker to speaker quickly and precisely.
Play some music and switch the amplifier to stereo mode – which we'd certainly stick with for music – and the Denon's detail retrieval and willingness to entertain come to the fore once more.
While we never want to make excuses for movie sound performance with a multichannel amplifier, we tend to find it necessary with stereo music. Here, listening to Apple Lossless rips of Andy Stott's Merciless streamed from iTunes using AirPlay, there's little by way of obvious compromise.
Good dedicated machines will always have the advantage, but there's nothing off-putting in the Denon's stereo music delivery, which makes the inclusion of Spotify, internet radio and AirPlay all the more useful – not to mention the digital USB input on the front for iOS devices. While this connection would charge Android devices, it wouldn't play music in our tests, so it looks like iOS-only here.
Denon Remote app
All this clever connectivity is topped-off by an excellent Denon Remote app, which affords you basic control of your amplifier from a tablet or smartphone (though there isn't a dedicated iPad app, so you'll have to settle for an enlarged version of the iPhone offering, see picture above).
That includes the ability to control your Spotify account in a much more manageable way compared with using the supplied remote: album artwork appears on your device, and on your TV screen, and all told it's slick, fast and easy.
That lively treble at high volumes is worthy of mention but elsewhere we can heap nothing but praise. Detailed and entertaining, punchy and powerful, the X2000 delivers good stereo playback alongside brilliant surround sound performance.
If you're in the market for a £500 AV receiver, there's always a hugely competitive list of products jockeying for attention – but there's no doubt that the Denon AVR-X2000 will be in the mix.
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What in Bob's Red Mill Is Coconut Flour?
Do you ever hear some people talk about different kinds of flour, new seeds, or see a word on a menu that you have no idea what it really is? Sometimes when I walk into the "natural foods" section of the grocery store, I see things that look pretty cool, but sometimes just keep walking because I'm not sure what they are or how I'm supposed to use them. I just wonder "What in the world is that? And how am I supposed to use it?" When I heard about coconut flour, that was exactly how I felt, except for this time, with Bob's help, I have done some research, experimented with some recipes, and feel like I know a little more about coconut flour. Hopefully I can share what I've learned with you so that you can add it to your shopping list and add a little healthy touch of coconut to your family's diet instead of walking on by.
What is coconut flour?
Coconut flour is a soft, flour like product made from the pulp of a coconut. It's actually a by-product made during the coconut milk making process. When making coconut milk, you have to soak coconut meat. That pulp is then dried out and ground into this powdery flour.
What are the health benefits of coconut flour?
Many people look to coconut flour to help create gluten free baked goods. Gluten free is definitely a great reason to use coconut flour, but that's not all it has to offer. Coconut flour is also extremely high in fiber with almost double the amount found in wheat bran. In just 2 tablespoons of coconut flour, there are 5 grams of fiber (20% of the recommended daily value) and 8 grams of carbs. Mayo Clinic says a diet with plenty of fiber can help keep you regular, help maintain weight, and lower your risk of diabetes and heart disease.
How do you cook with coconut flour?
Cooking with coconut flour can be a little tricky. I have had a couple of recipes completely bomb. Once you get the hang of it though, it's a super easy way to add nutrients and fiber to a ton of dishes. There are two things to keep in mind when working with coconut flour. Since it is so high in fiber, it requires a ton more moisture. There is also no equal substitution when working with coconut flour. You can usually substitute about 20% of the flour in a recipe for coconut flour and add at least 20% more liquid. My personal experience also says that when working with baked goods, you should also add about 3-5 eggs for every cup of coconut flour you are using. You can also add a tablespoon or two of coconut flour to sauces and gravies. It is a little clumpy so take your time when adding it in. Coconut flour has a naturally sweet flavor that can really add a nice little something extra to dishes.
Honestly, when you're beginning to bring coconut flour into your cooking, stick to already established recipes. Once you start to get a little more comfortable, you can begin to experiment. I speak from experience… botched recipes can be costly and a little disheartening. Practice with some great recipes online first. You can even check out my first great coconut flour recipe success: Whole Wheat Coconut Blueberry Muffins.
Resources for More on Coconut Flour
– Mayo Clinic article on benefits of high fiber diet
– Nourished Kitchen: A great blog with tips on baking with coconut flour
– Livestrong article on the benefits of coconut flour
– Bob's Red Mill coconut flour facts
– Bob's Red Mill Hangout on Google+: Tips for Baking with Coconut Flour
About Ashley – Ashley is a mom, wife, sister, daughter, and friend working to navigate through the mysterious world of Mommyia. Read more about her adventures at Momicles and follow her @Momicles2010.


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With Thursday's crucial vote in the U.S. House coming down in favor of a new four-lane bridge across the St. Croix River at Stillwater, the project appears to be moving forward. What will that mean for western Wisconsin?
Ellen Denzer, St. Croix County, Wis. planner, said there will be changes in the next five to 10 years.
St. Croix County isn't all a sleepy community. It's considered the fastest-growing county in Wisconsin. From 2000 to 2010, the county went from 65,000 people to 80,000, the largest percentage increase for the county in decades, Denzer said. A lot of that has been residential growth.
"There will definitely be some businesses and housing developments," she said. "But I think it will be more rural than you think; than some people worry about. And I think it will be that it will be done in a way that retains that rural look. People on this side of the bridge are a little worried about losing the rural look, too."