text: Park puts it in overdrive By Doug Smock December 21, 2012 Story Share Chip Ellis Winfield's Zach Fisher (24) is fouled by Wheeling Park's Theophilus Blackston (34) on a drive to the basket. CHARLESTON, W.Va. -- For 25 minutes and 9 seconds, Winfield made everything look easy against a young Wheeling Park team in their Hoops Classic game Friday at the Civic Center.But as soon as Zach Fisher's free throw gave the Generals a 37-20 lead, they seemed to forget what got them to a 17-point lead, and forgot how much pride the young men wearing "The Park" jerseys usually have. The next thing the Generals knew, they were staggered by a 16-0 run and buried 61-57 by the Patriots.Park (2-1) did much of its second-half damage with its reserves - Zach Phillips scored 10 of his 12 points and Trenton Smith scored all 10 of his in the final 12 minutes.That just happens to be when the Patriots flipped a virtual switch and dominated. Starting with a Smith fast-break basket with just under 4 minutes left in the third quarter, the Patriots outscored the Generals 29-13, hit 12 of 21 from the floor and forced eight of Winfield's 20 turnovers."We did a wholesale change of subs there. Things weren't working for us," said Park coach Michael Jebbia. "Winfield played harder than we did in the first half, they had more energy. We went with subs, and it got things going."For a stretch including the last minute of the third quarter and the first three-plus minutes of the fourth, everything was going right for the Patriots in their 16-point tear. Winfield (3-2) started the streak with two walking violations and Park's Andrew Kowalo hit a basket to cut the Generals' lead to 46-38 at the end of three quarters.Jebbia wanted the margin a little closer at that point, but he didn't expect his players to make up those eight points almost instantly. Luke Saseen, the team's only returning starter, hit a runner and Phillips banked in a basket while crossing into the lane. Smith hit two 3-pointers sandwiched around a Phillips runner and Saseen scored on the fast break, giving Park a 52-46 lead with just under 5 minutes left. After the Patriots hit their next two shots, completing a streak of nine made field goals in a row, the Generals couldn't recover.That had Winfield coach Pat McGinnis going overtime with a lengthy postgame speech that would have made Capital coach Carl Clark proud. (In fact, a Hoops Classic official gently nudged the Generals out of the locker so Clark and his Capital team could use it.)"[Park] stepped up the intensity in the second half, and we warned them about that. The game was far from over," McGinnis said. "We addressed it, too - we've got some people playing as individuals, not executing and not going where we tell them to. I think we could be a pretty decent team, but we've got to get some things worked out."Ryan Reinbarg led Park with 13 points, including two quick 3-pointers that set up the winning run. Saseen finished with 11 as the Patriots shot 45.1 percent.Winfield's Fisher led all scorers with 17 points, followed by Chris Turner with 16. Turner's late 3-pointer with a second left set the final score.The Generals shot 37.5 percent, dragged down by a 4-of-16 slump in the final 12 minutes.Reach Doug Smock at 304-348-5130, email@example.com or follow him at twitter.com/dougsmock. Story Share Story Share Trending Now 1 Innerviews: Dual-identity surgeon riding high in horse racing world 2 Huggins, WVU tap South Florida hoops talent 3 WVU seeking improvements during off week 4 Former State Police captain now chief in Winfield 5 Rod Run and Doo Wop brings classic cars, music to Boulevard for 12th year Kentucky's struggles no comfort for Herd Previous Story WVU looking for the right mix Next Story


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The US presidential election of 2016 is scheduled for 8 November 2016, where the 45th President of the United States will likely be determined. Discussions and debates surrounding the event have been charged, to say the least. This is an excellent opportunity to cut through the hype and the rhetoric to explore the nature and depictions of elections, both within reality and in fiction.
To be a part of this historic conversation, PopMatters seeks submissions about elections in popular media, including but not limited to: presidential elections as they are represented in the media, political elections within film and television; high-school / sorority elections in media; film policy shifts, pledges, and promises; award voting controversies; the sci-fi and western genres and elections; nominated / randomly / unwittingly selected participants; and electoral commentary in videogames, cartoons, literature and other media.

subset: commoncrawl


text: After months of, in this case, unintentional leaks, Triumph finally unveiled its new Speed Triple at the Intermot motorcycle show today. Of course, the company still hasn't uploaded pictures or information to its press site and the specs available on its main page are from last year, so we've been scrambling to bring you material. Finally, here's full-screen shots of the 2011 Triumph Speed Triple, check out the information that leaked last night for details.


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Cision recently published its annual State of the Media Report, which I find to be one of the most valuable resources for understanding changes in news media environment. The report is jam-packed with information about the current news media environment and how most journalists prefer to work (particularly around areas like social media and working with media relations professionals). If media relations is part of your job, I highly recommend you review Cision's report in detail.
Of course, since I know how busy media relations professionals can be (and since I'm such a swell guy), I've gone ahead and done the work for you. I reviewed the report in detail, and turned the most interesting findings into an actionable set of nine media relations tips you can use to improve your results in 2016 and beyond. Enjoy! [Read more…]


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Oct. 7, 2005
Quail Hunting Outlook Bright for Parts of Texas
AUSTIN, Texas — Quail hunters have enjoyed the rewards of ideal range conditions and above normal bird production during the last couple of years. Although hunting prospects are still favorable heading into the 2005-06 season, they probably won't measure up to recent years in a few locales where it has gotten dry over the summer.
Except for the Rolling Plains region, which continues to shine thanks to lush habitat and above normal bobwhite quail production, expectations this season should be tempered, according to state wildlife biologists, due to hot and dry conditions throughout much of the southern and central parts of Texas.
"I think we got spoiled the last two years with cool, moist summers and we're not likely to have that again for awhile," said Robert Perez, quail program leader with the Texas Parks and Wildlife Department. "Given the base of birds, with carryover from last year, we should have an average year. But, an average year in Texas is still better than most anywhere."
The statewide quail season runs from Oct. 29-Feb. 26. The daily bag limit is 15, 45 in possession. Legal shooting hours for all non-migratory game birds are 30 minutes before sunrise to 30 minutes after sunset. The bag limit is the maximum number that may be killed during the legal shooting hours in one day.
Ideal quail production occurs in years that remain wet and cool during the spring and early summer months because it extends the window of opportunity for reproduction, according to Perez. He noted hens typically would make as many nesting attempts as conditions allow until they pull off a successful clutch. This year, conditions became hot and dry from late spring through September over a good portion of the state, which could have an impact on extended nesting success.
"Based on field reports, Texas had a regular spring with moisture and quail paired up on time," he noted. "Emily provided some needed moisture in July, but that moisture didn't stay around long. I wouldn't say it's been an extended hatch, but we had a hatch."
South Texas is truly a semi-arid region where much of the annual variation in bobwhite quail populations can be attributed to the timing and amount of rainfall. Over much of South Texas, especially the western half, there was not enough soil moisture (significant rainfall events) to result in successful nesting, Perez noted. The eastern and northern portions of the region did receive enough spring moisture for normal spring nesting to occur and in areas under proper range management should have huntable numbers of bobs. TPWD field staff reported very little production in the mid to latter parts of the summer.
"Based on numerous reports, the best bobwhite hunter opportunities will be found in the pockets of good quail habitat under proper range management, which received adequate rainfall," he said. "I would recommend looking for healthy stands of native bunch grasses and an abundance of forbs."
Much of the Rolling Plains region of Texas experienced excellent range conditions for the majority of the spring and summer. There were was also a good amount of carry-over birds from last season and nesting conditions remained good to excellent over most of the summer. There are plenty of forbs (weeds) and insects (chick food) on the ground and hunting conditions should be excellent. Numerous field staff reported seeing differing size classes of broods throughout the summer, indicating a significant reproductive effort.
Bobwhite hunter opportunities should be plentiful, especially in the southern half of the region, which received the most favorable weather conditions.
In addition to the Rolling Plains region, the Trans-Pecos has received a third year of timely spring and summer rains. As a result, the number of scaled quail observed during annual TPWD quail counts is the highest for the region since 1981. Field staff report excellent production over the better part of the summer and are expecting an excellent season.
The western edge of the Edwards Plateau transitions into the Trans Pecos in an area called the Stockton Plateau where above average scaled quail production has been reported, as well.
Elsewhere around the state quail numbers in the Cross Timbers increased slightly from last year but still remain far below the long-term average for the region. During the past decade, cumulative effects of changes in the quality and quantity of bobwhite habitat have negatively impacted the abundance of quail at the regional level. However, there a certainly hunting opportunities at the local level where good quail habitat remains, especially in the westernmost counties of the region.
TPWD quail surveys also indicate bobwhite numbers in Gulf Prairies are also below the long-term average, but do not reflect bobwhite abundance in the southern Gulf Prairies (south of Victoria) where there are still larger landholdings of native rangeland. According to field reports these areas should have an above average quail crop.
For those who don't have access to private land or are on a budget there are ample opportunities to take part in the upcoming quail season on public land. Wildlife biologists at the Chaparral and James Daughtrey Wildlife Management Areas in South Texas predict there will be quality quail hunts early in the season. The Matador and Gene Howe WMAs in the Rolling Plains are predicting above average public hunting opportunity.
Public hunter opportunities can also be found at Elephant Mountain and Black Gap WMAs in the Trans Pecos. "If you did not get a chance to chase some blues last year, you definitely have another shot at it this year," said Perez. "Sturdy boots, dog boots, and a lot of stamina are recommended."
Access to hunting at these WMAs and others is available with the purchase of a $48 Annual Public Hunting Permit, which can be bought wherever hunting licenses are sold, online at http://tpwd.texas.gov/licenses/online_sales/ or by calling toll free (800) 895-4248. There is a $5 convenience fee for online and phone purchases.
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(5.4.16 i)


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Welcome to the National Portrait Gallery which through the visual arts, performing arts and new media, portrays poets and presidents, visionaries and villains, actors and activists whose lives tell the American story. Through the visual and performing arts, we celebrate leaders such as George Washington and Martin Luther King Jr., artists such as George Gershwin, activists such as Sequoyah and Rosa Parks…
Do you know the National Portrait Gallery shares with the Smithsonian American Art Museum one of Washington's oldest public buildings, a National Historic Landmark that was begun in 1836 to house the U.S. Patent Office.
The museum is open Monday through Friday from 11:30am to 7pm. The museum is closed on the 25th of December.
The museum is conveniently located above the Gallery Place-Chinatown Metrorail station (Red, Yellow and Green lines) at Eighth and F Streets, NW, D.C., 20001. Metro hours, fare information, and maps are available at www.wmata.com. The DC Circulator also serves the museum' Penn Quarter neighborhood. Hours, fare information and maps are available at www.dccirculator.com.
Enjoy your visit!
Jonathan, Innkeeper
American Guest House Bed and Breakfast
Washington DC Bed and Breakfast accommodations . We are centrally located, 10 minutes walk to DuPont Circle metro/subway, 1 mile north west of White House.


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OKLAHOMA CITY—A 34-goal scorer for the Edmonton Oilers last season, Jordan Eberle could have had his pick of European teams to play with during the NHL lockout. Could have, that is, except for the fact that because the 22-year-old winger has played only 147 NHL games, and is still on his entry-level contract, the Oilers were able to send him to the AHL.
As far as lockout gigs go, though, Eberle would not change a thing.
Justin Schultz: Young, unusual | Wild bet on Charlie Coyle, Mikael Granlund
"If I had the choice between here and Europe, I know a lot of guys in Europe would rather be here," Eberle told Sporting News. "It's a North American style game, not the international game. I've played over there (with Team Canada) and it's way different. We have a lot of guys here that are going to be in the NHL, so if you can have us all together, it gives us that extra energy as we're building our team. We still have a lot of work to be done."
The majority of the Oilers' future is in Oklahoma City, with Eberle, the club's 2008 first-round pick, joined by 2009 first-rounder Magnus Paajarvi, 2010 No. 1 pick Taylor Hall, and 2011 No. 1 pick Ryan Nugent-Hopkins. Along with those four forwards, the Barons have talented rookie defenseman Justin Schultz, signed this summer as a free agent out of the University of Wisconsin.
The only key cog of a prospective Edmonton renaissance who isn't in Oklahoma City is this year's No. 1 pick, Nail Yakupov, who cannot play in the AHL because of the league's age minimum, and went to the KHL in Russia rather than stay in North America to dominate the Canadian junior ranks, as he did the past two seasons with the Sarnia Sting.
Even though Oklahoma City's lineup is stacked with young, NHL-caliber talent, and the Barons have been hyped as the AHL's most exciting team in years, it has yet to translate to results on the ice. Oklahoma City is 5-4-1 through its first 10 games, presenting a similar challenge to what the core group faces in Edmonton: learning to turn talent into victories.
"I think we have all the pieces (with the Oilers)," Eberle said. "It's just a matter of putting it together. I think it's kind of the same situation here. We need to tighten things up in our defensive zone and tighten things up bringing the puck out. We have a lot of skill here, and we need to find a way to put it together. Once we do, I think the wins are going to start stringing along. We need to go into games expecting to win."
Winning isn't the only thing the young Oilers should expect. As their reputation grows, Eberle and his skilled teammates must keep their eyes open and be aware that opponents will target them. Last month, Eberle was lucky to escape serious injury after a knee-to-knee hit from Antoine Roussel of the Texas Stars. It won't be the last big hit he takes.
"When you play playoff hockey, all bets are off, and top players are going to create attention," Oklahoma City coach Todd Nelson said. "Teams are going to want to key on them, so they're going to have to learn to deal with it. They will, and they've had to deal with it before—in junior hockey, the Western Hockey League (where Eberle played his junior hockey) is still a tough league, and I'm sure Justin had to deal with it in college. They've dealt with it at that level, and they'll have to deal with it in this level and the NHL."
If Eberle in particular is a marked man in the AHL because of his NHL All-Star status, there also is a positive that goes with the territory of playing in a league that, even with an influx of young NHL talent this season, is below his skill level. Playing in Oklahoma City allows Eberle to grow as a team leader, and it is a challenge that he is embracing.
"I've never been a rah-rah guy, but as far as leading by example on the ice and working hard in practice, that's always something I've prided myself on doing," he said. "Guys are going to look to me because I've played National League games and done some stuff up there. I think the league here is a little different, but once we start playing better and clicking together as a team, and using five guys instead of one, it's going to be a lot better for us."
So far, it has clicked for Eberle, to the tune of six goals and five assists, hardly a surprise given what he has accomplished in the NHL, but notable nonetheless because it would be easy to relax and just try to stay healthy while waiting to return to top-flight hockey. But that's not his style.
"For me, it's always been easy to be motivated," Eberle said. "First off, in practice, we have so much talent on this team, it's easy. When you have that inner competition, it's going to make you work harder and make your team better. Playing in the AHL, we want to win hockey games. I want to win as many games as we can and do something special this year. We have that opportunity with the team we have, and we're looking forward to putting it together."
First in Oklahoma City, then in Edmonton.


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A recording I made on the 6 Train going uptown in New York City. As you can hear the train sits there more than a minute before it heads from 23rd Street onward. I used an iPhone 3G and the FiRe application which uploads directly to SoundCloud.
Check out my growing set of Field Recordings: click here


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Setting Up for Two More Reports
How will Lowe's (LOW) caution translate to Home Depot (HD)? It's a tough call, as I find Home Depot a little more attractive here -- but, overall, these two names are extraordinarily alike in terms of price-to-earnings ratios, debt levels, payout ratios, dividends and growth rates. So I have to anticipate a similar report in Home Depot, due Tuesday before the bell -- as well as a similar reaction in the shares.Home Depot (HD) -- Daily Source: StockCharts.com View Chart » View in New Window »
Home Depot does have a slightly different chart from that of Lowe's, but only in the fact it left a gap at the start of the year. I'm actually looking for a move toward that gap, or even a potential fill. Home Depot is showing two failed breakouts on the chart, but I think it would take something very negative to push shares much below the $62 or $63 area. Also, while I don't mind owning this stock, my approach on earnings here is still for a trade....280 more words left in this article. To read them, just click below and try Real Money FREE for 14 days.
There's no substitute for a trading floor to get great ideas, so Jim Cramer created a better one at Real Money and blogs there exclusively. We then added legendary hedge fund manager, Doug Kass, with his exclusive Daily Diary and best investing ideas. Staffed with more than 4 dozen investing pros, money managers, journalists and analysts, Real Money Pro gives you a flood of opinions, analysis and actionable trading advice found nowhere else, and allows you to interact directly with each expert.
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We are a Russian-based network of experienced, bilingual professionals with knowledge of the corporate environments in both the UK and Russia and the CIS. Our knowledge comes from hands-on experience serving major clients.
We are dedicated to providing exceptional service for clients from Russia and the CIS going to the UK as well as UK-based companies considering investment in Russia and the CIS. We serve clients' needs by utilizing the capabilities of our global organization.
What we do
- One point of contact for all prospective and existing clients to connect with EY's extensive UK network
- Identify appropriate internal recourses either in the UK or Russia to enable efficient, timely responses to all client needs across all service lines and geographies
- Identify new clients and arrange appropriate senior level meetings with EY partners
- Work closely with the UK Embassy, Russo-British Chamber of Commerce, Association of European Businesses and other appropriate agencies to promote UK-Russian trade and investment
- Access the experience of the UK Business Centre staff in operations for foreign companies entering the Russian marketplace
- Using software, enable clients to investigate different areas for investment in Russia and the Russian regions
- Bring external resources where needed to support our clients
- Preparation of Thought leadership covering different aspects and changes in the market and services updates
Our Services


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Recap of Last Year's "Other" Desserts
Some desserts don't fall into a major category, so I label them Other. Eventually, I'll update my labels and create a Cake and Pie label, but until then, here's my Top 5 list of "Other" desserts.
This Cinnamon Roll Monkey Bread was a concoction I dreamed up for a Bundt-Off. Yes, I have crazy friends, and yes, this is crazy delicious. I need to make it again…
When a special occasion popped up, I knew instantly that I wanted needed to make this Chocolate Overdose Cake. I topped it with chocolate covered strawberries to add some elegance. It was exactly what you'd expect from a layer of brownie, topped with chocolate mousse, topped with a chocolate cake layer, all overed in chocolate ganache.
When spring rolled around, I made this Lemon Raspberry Cake. It was the first time I had ever decorated a layer cake and I was pretty proud of how it turned out.
The Homemade Ding Dongs transported me back to a time of brown bagged lunches in the cafeteria of my middle school.
And I had to include Hubby's first attempt at baking on my list. He made this Strawberry Shortcake Cake for my birthday and did a great job at it!
4 Responses to "Recap of Last Year's "Other" Desserts"
The lemon raspberry cake looks awesome! I wish I could bake like you!
Yours is my new favorite blog! Everything looks absolutely delicious, I will have to make that Lemon Raspberry cake sometime 🙂 Oh, and I live in Wisconsin but visited Boston for the first time last year and LOVED it! Keep posting yummy recipes, have a great weekend!
I am planning on making the chocolate overdose cake for my hubby's birthday coming up in a couple of weeks. I wanna add a white chocolate mousse. So, I'm thinking about cutting the cake in half and adding it there…what do you think? Would that work? =)
Ashley – I think that would work just fine. Let me know how it turns out.


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15 U.S. Code § 2057a - Banning of butyl nitrite
Except as provided in subsection (b), butyl nitrite shall be considered a banned hazardous product under section 2057 of this title.
For the purposes of section 2057 of this title, it shall not be unlawful for any person to manufacture for sale, offer for sale, distribute in commerce, or import into the United States butyl nitrite for any commercial purpose or any other purpose approved under the Federal Food, Drug, and Cosmetic Act [21 U.S.C. 301 et seq.].
The Federal Food, Drug, and Cosmetic Act, referred to in subsec. (b), is act June 25, 1938, ch. 675, 52 Stat. 1040, as amended, which is classified generally to chapter 9 (§ 301 et seq.) of Title 21, Food and Drugs. For complete classification of this Act to the Code, see section 301 of Title 21 and Tables.
Section was enacted as part of the Anti-Drug Abuse Act of 1988 and also as part of the Comprehensive Alcohol Abuse, Drug Abuse, and Mental Health Amendments Act of 1988, and not as part of the Consumer Product Safety Act which comprises this chapter.
LII has no control over and does not endorse any external Internet site that contains links to or references LII.


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May 24, 2004
Saltwater Anglers Asked To Share Attitudes About Fishing
AUSTIN, Texas — The Texas Parks and Wildlife Department is responsible for understanding not only the biology of coastal fisheries systems, but also the social and economic impacts on the resource as well.
Texas' saltwater angling community has been booming in recent years to the tune of about 2,000 new anglers a month.
TPWD regularly conducts surveys to get a feel for the pulse of the Texas saltwater angler. The information not only provides a snapshot of the Texas fisherman, which is useful in developing fisheries management strategies and regulations, but is also factored into a nationwide overview. Every five years, state survey findings are included in the U. S. Fish & Wildlife Service and the U. S. Bureau of the Census publication The Economic Importance of Hunting, Fishing, and Other Outdoor Activities.
In cooperation with Texas A&M University, Department of Wildlife and Fisheries Sciences, TPWD's Coastal Fisheries Division is currently doing a Web-based survey to update its assessment and to gauge the opinions of Texas recreational fishermen about regulations and to estimate the economic benefits of recreational fishing to the Texas economy.
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(5.4.16 i)


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Springer scratched from lineup with knee soreness
PHOENIX -- The Astros scratched outfielder George Springer from the lineup due to right knee soreness before Monday's game against the D-backs at Chase Field.
The team announced that Springer is day to day with the injury.
Alex Presley took Springer's place in right field, and fellow rookie Jon Singleton moved to No. 3 in the order to replace the 24-year-old outfielder.
Presley went 0-for-3 in his place in the Astros' 4-3 win on Monday.
After the game, manager Bo Porter said he took Springer out to allow him to get treatment on the knee, which has been bothering him. He said whether or not Springer plays against the D-backs on Tuesday will depend on how Springer feels after receiving treatment Monday.
"He was able to get treatment all day today, and we'll come here tomorrow and see how he feels and go from there," Porter said.
Springer has been one of the Astros' best hitters this season. He is currently batting .251, but has a .843 on-base plus slugging mark. He has 12 homers and 35 RBIs through the first 47 games of his career.
Springer was named the American League's Rookie of the Month for May after hitting .294 with 10 home runs.
Brian McTaggart is a reporter for MLB.com and writes an MLBlog, Tag's Lines. Follow @brianmctaggart on Twitter. Adam Lichtenstein is an associate reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.


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After California, New York is the second-largest producer of wine in the U.S. It's home to 4 wine growing regions and 8 different appellations. Each of New York's wine regions has a distinct climate and is known for a particular style of New York wine.
The eastern end of Long Island is known for its North Fork appellation, which produces Bordeaux-style reds. Weather here is affected by the Peconic Bay, Long Island Sound, and, of course, the Atlantic Ocean. These Gulf Stream-influences moderate the temperature and create a maritime climate and long growing season.
New York's Finger Lakes region is sometimes (unfairly) compared to Germany's Rhine. This area experiences short growing seasons and downright frigid winters, but the deep, narrow lakes provide enough of a moderating effect to keep the industry intact. The region's steep hillsides provide good sun exposure and, almost as important, excellent drainage to help ward off frost. Needless to say, cool-climate varieties have fared best, particularly Riesling. The Finger Lakes also produce a number of sparkling and ice wines.
The Hudson River region is home to the country's oldest continually running winery, Brotherhood Winery, which was founded in the 1830s. The Hudson River's north-south direction helps draw moist ocean breezes into the river valley and thus moderate the potentially harsh growing conditions (which range from excessive heat to extreme cold). In recent years, New York wine producers and grape growers have begun finding success with hearty clones of Chardonnay and Cabernet Franc.
The best Chardonnays in the world continue to arrive from the region where the grape first emerged: the chalk, clay, and limestone vineyards of Burgundy and Chablis. While the origins of the grape were disputed for many years, with some speculating that the grape came all the way from the Middle East, DNA researchers at the University of ~California Davis proved in 1999 that Chardonnay actually developed, most likely, in eastern France, as a cross between a member of the "Pinot" family and an ancient, and nearly extinct variety called Gouais Blanc.
Wine lovers who have come to think of Chardonnay as weighty and thick will find Chablis a revelation. When grown in the cool, clay-and-chalk soils around the sleepy town of Chablis, at the northern reach of Burgundy, Chardonnay is transformed into one of the world's most cerebral and distinctive white wines. With its brisk citrus character, floral lift, and incisive minerality, Chablis is at once sharper and more delicate than white Burgundy from the Cote d'Or nearly 100 miles to the southeast -- and potentially at least as long-lived. And Chablis is about as far removed from fruit and oak-driven New World Chardonnay as a white wine can be.
As recently as fifteen years ago, the American market had an unquenchable thirst for Chardonnay, particularly for examples from California. Today, although Chardonnay is still the most widely planted variety in California in terms of acreage, serious wine aficionados rarely talk about Chardonnays other than those from a handful of specialist producers. Even at the level of the mass market, many consumers have tired of overly alcoholic, over-oaked, and clumsy wines, not to mention neutral, technically correct but soulless examples. Many wine drinkers have moved on to fresher, less oak-influenced white wines such as Sauvignon Blanc. This is a shame, as the trend has turned toward brighter, better-balanced Chardonnays from cooler sites, with crisper fruit aromas, more soil character, and less reliance on new barrels for flavor.
Still, it's a two tier market. A relative handful of producers make wonderfully layered, complex Chardonnays that can easily hold their own against more expensive white Burgundies, at least in their early years in bottle. These wines, which can be richer than dry whites have any right to be, are among the most impressive wines made in California today and continue to be hotly pursued by collectors. The rest of California's Chardonnay producers compete for the attention of consumers who are no longer obsessed with this grape.
But there are now many excellent choices available, many from cooler areas. Lower elevations of Napa Valley have virtually been abandoned as appropriate sites for Chardonnay. Now the best wines come from the Russian River Valley and further west in Sonoma County; Carneros, the Anderson Valley to the north; and the Central Coast, especially the windy western portion of Santa Barbara County. Today, there are fewer blowsy, tropical-fruity Chardonnays with the alcohol levels and flavors of a pina colada and many more wines with fresher stone and citrus fruit elements, mineral notes, and restrained oak spice.
While most California Chardonnays should be consumed within two or three years of their release, the top examples can give pleasure for four to eight years, although it is debatable whether these wines gain more in texture and complexity than they lose in early fruitiness.
Just north of California, Chardonnay is by a wide margin Washington's most popular white variety in terms of vineyard acreage, yet the number of truly concentrated and consistently excellent wines is limited. Some of the most interesting Chardonnays come from the cooler Columbia Gorge viticultural area, which spills over into Oregon: the Celio vineyard in particular is the source of some very fresh wines that often show a juicy nectarine component.
On the other side of the world, the export market for Australian Chardonnay was driven in the 1980s by what is called the Show Reserve style -- attention-getting wines made for competitive tastings, usually marked by lavish oak spice, superripe tropical flavors, thick textures due to high alcohol, and sometimes even a bit of residual sugar to seduce early tasters. These wines can be difficult to take, either at the table or on their own. For better or worse, though, this is the style that defines Australian Chardonnay for many North American wine lovers. Fortunately, many producers have adjusted their wine-making regimens to make fresher, more vibrant, and energetic Chardonnays. The most obvious strategy has been to plant Chardonnay in regions and in microclimates better suited to making elegant wines with real flavor intensity than those with brute strength. Western Australia, particularly the Margaret River region, has emerged as a top growing area for Chardonnay, with superb wines also being produced in Victoria and the Adelaide Hills. Tasmania is showing promise as well.
Even if it is the country's second most important variety in terms of production, Chardonnay in New Zealand is of limited interest to international markets. Few sites appear capable of producing truly distinctive Chardonnay wines, and full crop levels and a high percentage of young vines further limit the grower's ability to transmit soil character into the bottle. Some wineries slap a lot of oak on their Chardonnays, with the result that the wines can be more about wood than about the variety. But fresh, unoaked Chardonnays made in a Sauvignon style have attracted a following in North America, especially where prices are reasonable.
2003 had 6 regions scored 95 or above. Cote Rotie (Northern Rhône) and Port, both got the highest score, with a 96.
Other regions that scored 95 points or higher were Medoc, Sauternes, South Africa, St Julien, Pauillac, and St Estephe.
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BLACKBURN with Darwen Council have been praised after Ofsted inspectors gave a care home a Good rating.
The local authority home provides short-break care for up to five disabled young people — Ofsted protected the name and location of the facility in the report.
The judgement said that the children's home has demonstrated continued improvement in the quality of care and outcomes for children and young people.
At the last inspection in 2013, the facility was also judged Good, but the council was advised to make more storage space available in young people's rooms and to log medication more formally.
The latest report said: "Young people experience safe, nurturing care in a homely environment. They continue to make good progress during their short breaks. Since the last inspection, the home has made further improvements to children and young people's quality of care.
"Children and young people continue to enjoy many opportunities to engage in social activities both home and away."


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Ambulatory Surgery of Lower Extremity Varicose Vein
Recruitment status was: Recruiting
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
OBJECTIVE: To retrospectively analyze the results of ambulatory treatment on Taiwanese patients with primary varicosities of the lower extremities including the use of endovenous laser, phlebectomy, and sclerotherapy.
METHODS: We routinely used tumescent anesthesia and ultrasound-guided approaches for the application of endovenous laser. Vein access was achieved by either a percutaneous or stab wound. The laser power was usually 10 - 20 watts; laser treatment usually was begun from 4-10 cm below the saphenofemoral junction, and stopped around the knee, not over 10 cm below the knee. In the same operation, we used Mueller's phlebectomy and/or sclerotherapy if there were prominent branch varicosities. We instructed each patient to walk around immediately after the operation, to go home, and to come back 1-3 days later for follow-up. Ultrasound scan and venous function follow-up was scheduled at 1 month, 6 months, 12 months, and then annually.
|Varicose Veins
|Study Type:
|Study Design:
|Observational Model: Case-Only
Time Perspective: Retrospective
|Ages Eligible for Study:
|Child, Adult, Senior
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
|Sampling Method:
|Probability Sample
Inclusion Criteria:
- All patients with varicose veins who underwent endovenous laser treatment for GSV reflux in our hospital were reviewed
Exclusion Criteria:
- poor general health, inability to walk, active inflammation of varicose veins, deep venous occlusion disease, hypercoagulability, pregnancy and breast-feeding.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00702897
|Contact: Chih-Yang Chan, ME, PhD
|Far Eastern Memorial Hospital
|Taipei, Taiwan
|Contact: Chih-Yang Chan, MD, PhD 886-8966-7000 firstname.lastname@example.com
|Responsible Party:
|Far Eastern Memorial Hospital
|ClinicalTrials.gov Identifier:
|NCT00702897 History of Changes
|Other Study ID Numbers:
|Study First Received:
|June 18, 2008
|Last Updated:
|June 19, 2008
Additional relevant MeSH terms:
Varicose Veins
Vascular Diseases
Cardiovascular Diseases
ClinicalTrials.gov processed this record on September 21, 2017


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Cutlery connoisseurs value Shun knives because of their extreme sharpness and good looks. This superbly crafted, top quality brand is made in Japan by knife experts, trained to make only the best. Knives are one of the most important tools for any chef, home or pros, shouldn't you have the best? When you invest in a Shun knife, it comes with lifetime free sharpening and a lifetime guarantee. Compare Shun knives.
Stunningly beautiful, Kershaw Shun Classic knives have a strong stainless steel core that's corrosion-resistant. 32 layers of additional steel and metals are bonded to it for sharpness, durability and beauty. The ergonomic Shun handle is an easy-to-clean blend of resin and hard birch wood.
Shun Classic Pro knives are made in the traditional Japanese style with single-bevel blades forged from a single piece of steel. This traditional design is easy to sharpen and maintain with a whetstone. Crafted in Japan, these knives have a lifetime warranty.
Shun Premiere knives are extremely sharp and durable. They feature a hand-hammered finish which not only looks good, it helps to keep foods from sticking to the blade. A warm walnut finish on the germ-resistant resin and wood handle adds to the rich look of the Shun Premier knives.
Shun Reserve knives are made in Japan and combine Shun's special crimson and black PakkaWood handles with a striking Damascus blade appearance. They're also clad with 32 layers of stainless steel and have a super-sharp powdered steel edge that keeps its edge for longer.
Shun knives are always innovating. We especially love their latest creation, Kanso. These incredibly sharp knives have a stunningly rustic handle made from Tagayasan wood. The blade, too, also evokes a rustic feel with a unique heritage finish. Made in Japan.
Shun Dual Core was named "Kitchen Knife of the Year" by the Blade Show. Dual Core is Shun's most innovative and sharpest style. Of course, made in Japan!
You can save as much as 20 percent when you purchase a knife set vs. buying individual open stock knives. Browse our complete selection of Shun knife block sets, ranging from 6 piece to 23 piece cutlery sets.
These Shun knives have traditional Japanese shapes and construction. Shun Blue has a core of carbon steel totally enveloped with stainless steel, so you can enjoy great sharpness, easier re-sharpening and low maintenance. Blue steel knives from Shun are made in Japan and have a lifetime warranty!
Made in Japan, Sora cutlery from Shun features the same super-sharp steel edge of their Classic series at a more affordable price. Sora blades feature a combination of a stainless steel blade with a VG10 "super steel" edge for excellent performance.
Perfect for any occasion, Shun knife gifts sets are well priced and great performing. A Shun cutlery set makes a great hostess gift, especially at holidays. Each knife set comes in a high quality wooden presentation case.
Save big on these specially priced Shun knives available only for a limited time.
Keep you Shun knives ready to use at all times. A sharpening steel will re-align the edges of the knife and reduce the need for sharpening. Specially made Shun sharpeners and whetstones are made to handle the 16 degree Asian angle that's on your top quality Shun cutlery.
Protect and safely store your knives with a variety of Shun cutlery storage options. Choose between knife blocks, trays, magnetic knife holders or portable professional knife cases, all made to meet Shun high quality standards.
Keep your Shun knives sharp with a Chef's Choice or Edgeware electric knife sharpener. We also recommend using a Henckels sharpening steel each time you use a knife. A steel gently straightens the knife blade. It will help to keep knives in good shape. They won't need as frequent sharpening.


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The Iris EF radiator belongs to the latest generation of infrared system high power radiators for the wireless Iris audio system. An electrical signal supplied from the Iris TS infrared control unit is converted into infrared light invisible to people and radiated into the room. The signal to be transmitted can comprise up to 16 channels in the range of 2 to 6 MHz (band IV). For installation a separate mounting bracket is available. Up to 30 Iris EF radiators can be connected to one Iris TS control unit in a daisy chain. If the Iris EF radiator does not receive a signal, it automatically turns into the standby mode. When the temperature of the radiator is too high, the system will automatically switch from full power to half power. If the temperature is still too high, the radiator will be switched to stand-by mode.
beyerdynamic GmbH & Co. KGTheresienstr. 8D-74072 Heilbronn
Phone: +49 (0)7131 - 617-400E-mail


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|Page (1) of 1 - 02/26/13
|email article
|print page
Dallas, TX (PRWEB) February 26, 2013
Using mobile technology for faster delivery, WirelessDefensiveDriving.com has just released new Texas defensive driving podcasts to cover Texas driving rules and skills needed to negotiate the traffic and highways around the Lone Star State.
Keeping safe driving skills sharp requires continuous improvement and retraining to avoid complacence and over confidence. These defensive driving podcasts are made in a forum talk style, with humor and high quality production, the drivers will find them entertaining and engaging. It is easy to put the defensive driving skills to use. These skills should be practiced every time someone gets behind the wheel of a vehicle says Mr. Collins, founder and instructor of WirelessDefensiveDriving.com Defensive Driving Texas.
Classic rules of the road and new safer driving tips on how to be safe, are revisited and covered in the new podcasts. These new driving course materials are fully scrutinized and approved by the Texas Education Agency, the over-seeing state agency in charge of defensive driving industry regulation.
Some of the topics covered are: Alcohol and safety problems, driving emergency, defensive driving strategies, laws and procedures, factors influencing the driving performance, seat belts, helmets and airbags, perceptual skills and special skills for driving.
The new podcasts are also available for streaming on YouTube http://goo.gl/eFkBe or directly from iTunes to be downloaded to any mobile device and take on the road, same way a driver would listen to an audio book. Of course the same podcast can be used on regular laptops or desktops.
The new delivery format allows the material to be updated constantly and delivered to our fellow drivers in real time. When new statistics are released and new or changed laws are approved, the defensive driving course materials can be updated quickly states Mr. Collins.
Mr. Collins opened the first online defensive driving Texas course over a decade ago and has taught many Texas drivers how to become safer, better drivers. For more information please contact WirelessDefensiveDriving.com online.
5470 West Lovers Lane
Dallas, TX 75209
Office: 888-925-9501
Read the full story at http://www.prweb.com/releases/defensive-driving-texas/wireless-mobile/prweb10463930.htm.
Page: 1
Keywords:insurance,health insurance,tourism and leisure,lifestyle and leisure,tourism,travel and commuting,lifestyle (house and home),consumer goods,consumer issue,consumer confidence,automotive equipment,consumer issue,family,family planning,lifestyle and leisure,lifestyle (house and home),internet,consumer goods,consumer issue,consumer confidence,consumer issue,money and monetary policy,family,family planning,personal investing,personal service,,personal income,personal weapon control,personal data collection
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text: The West Side's 'school of the future' By Mackenzie Mays September 26, 2012 Story Share Chip Ellis Preparation work continues at the site of the new school on Charleston's West Side. The school, which is expected to open in 2014, is under construction in an area north of Wood Road and Edgewood Country Club. Courtesy illustration The West Side's new "school of the future" as depicted by ZMM Architects and Engineers, the Charleston firm that is designing the school. It is expected to open by the fall of 2014. CHARLESTON, W.Va. -- The West Side's new $21 million school will be mostly composed of large "exploratory centers" instead of standard classrooms, and will offer a new type of integrated curriculum that emphasizes learning and technology that allows students to direct their own learning.The new "museum-like," 52,000 square-foot "school of the future" planned near Edgewood Country Club is set to welcome students by fall 2014, and will consolidate the oldest buildings in the district, J.E. Robins and Watts elementary schools.Four large instructional centers will house 60 to 75 students at a time, with four to five teachers guiding the students. Two of the exploratory centers will be for second- and third-graders and two for fourth- and fifth-grade students. They'll feature space for art and science projects, a performance arena and a shared library and media center. Each exploratory center also will host three individual classrooms for direct math and reading instruction.Sliding doors and moveable partitions will allow for flexibility if teachers need to temporarily separate the classrooms. Pre-kindergarten through first-grade students will remain in a traditional classroom setting in order to focus on early literacy, math and socialization skills.Kanawha County Schools Superintendent Ron Duerring expects the unique school to be unlike anything the area has seen before."Like a children's museum, kids will have a variety of interesting areas to work with and explore. It's different than anything we've done. It's the first time we've actually designed the building to make it fit the curriculum, rather than making it fit the building," he said. Each student will have access to a personal wireless device to check their daily schedules, participate in online independent studies and provide instructors with immediate feedback of their progress."It's about self-directed learning. Kids are going to take primary responsibility, and the teachers will be on the side, guiding them through the processes of researching and experimenting," Duerring said.The new school will also help students learn about environmental and health issues.Signs throughout the building will monitor the school's energy use, and students will learn about air quality, efficient HVAC systems, solar power and recycling. "The building will be a learning tool in and of itself. Even a section of the wall will be exposed to show how buildings are constructed," said Jane Roberts, assistant superintendent for elementary schools. "We're trying to help students develop all sorts of skills."Each area also will have direct access to outdoor instructional and recreation spaces.The learning environment will teach students a lot about teamwork and the real world, too, Roberts said. "Teachers will be working together and sharing responsibilities. They will be able to learn from each other even though they all have different styles of teaching. That family unit is going to be very beneficial for the children," she said.Teachers will undergo staff development and will be asked to make a three-year commitment to the school to ensure effectiveness.Last week, the state School Building Authority gave Kanawha County another $1 million to finish the project when they voted to help close a $2.8 million budget gap caused by complications with building on the hilly terrain.Kanawha County Schools will contribute a total of about $11 million to build the new school."This is a really unique school, and this has been a new experience for everyone involved," said Adam Krason with ZMM Architects and Engineers, the firm that's working with the state School Building Authority on the project. "But because of the many discussions about the funding it would take, the focus has never really been on what's actually going to happen inside the school."It's time for people to focus on what a great learning opportunity this is for students," Krason said. Construction is set to begin in November.Reach Mackenzie Mays at firstname.lastname@example.com or 304-348-5100. Story Share Story Share Trending Now 1 Deer in 8 WV counties found dead from EHD 2 New company planning $73M synthetic fuel plant in Greenbrier County 3 'Heroin(e)' spotlights women helping combat Huntington's drug crisis 4 YWCA Charleston's Women of Achievement to be honored in March 5 Area EMS workers return from assisting with Irma recovery W.Va. Senate campaign turns ugly Previous Story AARP names top volunteer Next Story


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Tennis championships
Division I
Torrey Pines 11,
Rancho Bernardo 7
Division II
Canyon Crest 13,
Cathedral Catholic 5
Division III
La Jolla 13,
La Jolla Country Day 5
Canyon Crest was making its first appearance in a San Diego Section boys tennis final. The Ravens knew they faced a big task in nemesis Cathedral Catholic for the Division II championship.
The Dons had been instrumental in eliminating Canyon Crest from the playoffs the past seven years. In fact, neither the Ravens boys nor girls tennis teams had ever beaten Cathedral Catholic — until Friday.
Canyon Crest defeated the Dons 13-5 at the Barnes Tennis Center to win its first boys section title in any sport since the school opened in 2004.
Leading the way for the Ravens (15-5) was the No. 3 doubles team of Trey Hahn and Mark Feldgreber, who rallied from down a match point to beat Cathedral Catholic's No. 1 team of Matt Eisendrath and Matt Rosi 7-6 (9-7).
"That was extraordinary," said Canyon Crest coach Christopher Black. "Winning a set like that really sets the tone for the rest of the match. They stepped up big time. It was unbelievable."
Feldgreber, a junior, attributed the doubles win to perseverance and working together.
"Picking each other up when we were down," he said.
His partner was happy to be part of history.
"This was an amazing win," Hahn said. "We haven't done this ever and we've lost to the same team four years in a row. Today was a team effort. We all played well and got the job done."
The gravity of beating Cathedral Catholic coach Ron Marquez and the Dons was not lost on Black.
"We've never beaten Ron before," said Black, who got a little choked up when reflecting on the accomplishment. "I'm just so happy for these guys."
Black also credited assistant coach Larry Belinsky.
"Would not have been able to do it without him," he said.
In Division I, it was powerhouse Torrey Pines (22-2) facing two-time defending champion Rancho Bernardo (18-6) for the fourth straight time.
The Falcons returned to their familiar perch, beating the Broncos 11-7. Torrey Pines got it done by winning all but two of its doubles matches. Another key win was J.P. Boyd's singles triumph over Rancho Bernardo's No. 1 player, Tyler Pham, 6-2.
"That was kind of a surprise," said Rancho Bernardo coach Mike Parrinello, who noted that Pham has been dealing with a back injury.
Parrinello, somewhat tongue in cheek, told longtime Torrey Pines coach Anne Meigs: "All's right with the San Diego tennis world now — Torrey's there on top and we're a close second."
The No. 1 Falcons doubles team of seniors Adam Levie and Connor Eck swept their matches.
"It feels amazing," said Levie, a senior. "We wanted to go out with a bang and we got it. It feels so great. We've worked a lot on doubles and it really paid off."
In Division III, La Jolla avenged last year's championship loss to La Jolla Country Day. The Vikings routed the Torreys 13-5, winning all but two of the singles matches en route to their state record 43rd team title in boys tennis.
Third-year coach Matthew Previdi noted the growth of him and his players.
"I have far from mastered high school coaching," he said. "However, just like myself, every year that we show up we get one step further, one bit better. And this year, we finally got it done."Copyright © 2017, The San Diego Union-Tribune


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Judge Dredd Defies New Readers Not To Jump On '2000 AD' With Latest Issue
As it is prone to do perhaps more often than some of its American competition, British sci-fi weekly 2000 AD has designed its latest issue to be especially welcoming to new readers. Four brand new stories begin in this week's 2000 AD Prog 1850, each meant to introduce audiences to the unique blend of art, attitude and insanity that can typically be found every week in "the galaxy's greatest comic." Among them, a new Judge Dredd strip as well as new work by Al Ewing (Mighty Avengers), Pat Mills (Marshal Law), Ian Edginton (Victorian Undead), and INJ Culbard (The New Deadwardians).
The new-reader-friendly prog is part of a concentrated effort to raise awareness of 2000 AD and Judge Dredd in particular so as to persuade the powers that be that a Dredd movie sequel is something they should put into production at once. That effort includes an official Dredd sequel petition and the latest issue of Judge Dredd Megazine, which introduces a new strip that will continues the continuity of the cult favorite Karl Urban film.


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YHA - Youth Hostel Baia del Corallo
The Youth Hostel Baia del Corallo in Palermo is part of the Hostelling International association of Hostels in Italy.
Palermo, the light-coloured houses, the illuminated trees like swarms of fireflies: this was Goethe's impression, trying to decribe a city that fills travellers eyes.
When the look can wander from a wonderful gulf to the mountains, from superb palaces to rare monuments, when the spectacle of nature merges with architecture, travellers eyes stop judging, just observe. A city that just for its colours, climate and scents was loved indistinctly by Phoenicians, Normans, Romans and Arabs.
Going out of the hostel, there are many possible itineraries, almost infinite. You can walk to 'Piazza Vigliena', also named 'The Sun Theatre', reaching in a short time to 'Cassaro', as the Arabs called the most ancient fortification of the city. Few further steps and you can find the Norman Palace and Cathedral, real architectural jewels.
The reception is open for check in from 8.00 to 10.a.m. and from 15.00 to 23.00 Please if you think to arrive after 22.00 o'clock tell us at least 5 days before
Please note, if you are not a Member of Hostelling International there is an extra charge so you become a HI member, for a year.
Availability & RatesTo view availability and prices please select dates and click 'Update Dates'
Hostel Facilities & Policies
- Bar
- Bicycle parking
- Breakfast Not Included
- Cable TV
- Café
- Common Room
- Telephone/Fax Facilities
- Free WiFi
- Hair Dryers For Hire
- Hot Showers
- Linen Included
- Luggage Storage
- Parking
- Restaurant
- Towels For Hire
- Towels Not Included
- Washing Machine
Cancellation PolicyThis property has a 1 day cancellation policy. Failure to cancel within this time will result in a cancellation charge equal to the first night of your stay.
DirectionsShow MapHide Map
Public transports: 20 metres from
628 bus stop
Railway station: T.Natale 2 Km
International airport: Palermo -Falcone e Borsellino- 15 Km
Boat: Palermo 12 Km


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Topic: First Day of Chemo
After the consult visits, the questions of which chemo treatment plan, and even the unexpected trip to ER due to heightened pain levels this weekend, it is time. My wife begins chemo today (Gem/Cis). it's been a crazy period since her diagnosis. At least we are now starting to fight back. We are ready to begin.


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Safety and Immunogenicity Study of Candidate HIV-1 Vaccine Given to Healthy Infants Born to HIV-1-infected Mothers (PedVacc002)
The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified September 2009 by Medical Research Council.
Recruitment status was: Recruiting
Recruitment status was: Recruiting
Medical Research Council
European and Developing Countries Clinical Trials Partnership (EDCTP)
Information provided by:
Medical Research Council
ClinicalTrials.gov Identifier:
First received: September 21, 2009
Last updated: June 15, 2011
Last verified: September 2009
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Primary: Safety and immunogenicity of MVA.HIVA vaccine in 20-week-old healthy Kenyan infants born to HIV-1-infected mothers.
- HIV-1 immunogenicity comparison between MVA.HIVA and age-matched unvaccinated control arms in each cohort (breastfeeding or formula feeding)
- HIV-1 immunogenicity comparison between breastfeeding and formula feeding infants receiving MVA.HIVA
- HIV-1 immunogenicity comparison between breastfeeding and formula feeding infants in the age-matched unvaccinated control group
- Comparison of responses to certain Kenyan Extended Programme on Immunization (KEPI) vaccines (OPV, DTP, HBV, and HiB) between MVA.HIVA versus age-matched unvaccinated controls in each cohort, between breast versus formula feeding infants in the age-matched unvaccinated control group, and between breast versus formula infants receiving MVA.HIVA
- Comparison of immune activation and phenotypic profile of lymphocytes between breast and formula feeding infants in each cohort (MVA.HIVA and age-matched unvaccinated control)
- Build capacity for Infant HIV-1 Vaccine Clinical Trials Centre in Nairobi, Kenya.
|HIV-1 HIV Infections
|Biological: MVA.HIVA
|Phase 1 Phase 2
|Study Type:
|Study Design:
|Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Outcomes Assessor)
|Official Title:
|An Open Randomized Phase I/II Study Evaluating Safety and Immunogenicity of a Candidate HIV-1 Vaccine, MVA.HIVA, Administered to Healthy Infants Born to HIV-1-infected Mothers
Resource links provided by NLM:
MedlinePlus related topics: HIV/AIDSU.S. FDA Resources
Further study details as provided by Medical Research Council:
Primary Outcome Measures:
- For safety and reactogenicity: Actively and passively collected data on adverse events. [ Time Frame: Up to 28 weeks after vaccination ]
Secondary Outcome Measures:
- For immunogenicity to KEPI vaccines: Antibody levels to specific vaccines as measured by ELISA. [ Time Frame: 1 week before and 1 week after vaccination ]
- For immunogenicity to MVA.HIVA: Frequency of IFN-γ-producing cells determined in an ELISPOT assay after overnight stimulation with a pool of HIVA-derived peptides. [ Time Frame: Up to 24 weeks after vaccination ]
|Estimated Enrollment:
|Study Start Date:
|November 2009
|Estimated Study Completion Date:
|October 2011
|Estimated Primary Completion Date:
|July 2011 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: Vaccinees
18 breast-fed and 18 formula-fed infants at the age of 20 weeks
Biological: MVA.HIVA
1 dose of 5 x 10^7 pfu of MVA.HIVA administered intramuscularly
No Intervention: Controls
18 breast-fed and 18 formula-fed infants at the age of 20 weeks
|Ages Eligible for Study:
|up to 3 Days (Child)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Infant Inclusion Criteria
- Healthy infants
- < 3 days of age (day of birth = Day 0) at enrolment
- Birth weight > 2500 grams
- Born to an eligible woman
- Written informed consent by parent
Infant Exclusion Criteria
- HIV infection, as determined by a filter paper and/or RNA test prior to vaccination.
- Participation in any other HIV-1 vaccine or drug trial.
- Failure to receive all standard KEPI immunizations according to national immunization programme.
- Weight for age z-scores outside of 2 standard deviations of normal at the time of vaccination.
- Acute disease at the time of vaccination (acute disease is defined as the presence of a moderate or severe illness with or without fever). All vaccines can be administered to persons with a minor illness such as diarrhoea, mild upper respiratory tract infection with or without low-grade febrile illness, i.e., temperature of <37.5 °C).
- Axillary temperature of ≥ 37.5 °C at the time of vaccination.
- Any clinically significant abnormal finding on screening from biochemistry or haematology by the time of vaccination.
- History of allergic disease or reactions likely to be exacerbated by any component of the vaccine, e.g., egg products.
- Presence of any underlying disease that compromises the diagnosis and evaluation of response to the vaccine.
- Any other on-going chronic illness requiring hospital specialist supervision.
- Administration of immunoglobulins and/or any blood products within one month preceding the planned administration of the vaccine candidate.
- Any history of anaphylaxis in reaction to vaccination.
- Research Physician's assessment of lack of willingness by parents to participate and comply with all requirements of the protocol, or identification of any factor felt to significantly increase the infant's risk of suffering an adverse outcome.
- Likelihood of travel away from the study area.
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00981695
Please refer to this study by its ClinicalTrials.gov identifier: NCT00981695
|Contact: Walter Jaoko, MB MTMed PhD
|Kenyatta National Hospital
|Nairobi, Kenya
|Principal Investigator: Walter Jaoko
Sponsors and Collaborators
Medical Research Council
European and Developing Countries Clinical Trials Partnership (EDCTP)
|Study Director:
|Tomas Hanke
|Medical Research Council
|Principal Investigator:
|Walter Jaoko
|University of Nairobi
|Principal Investigator:
|Grace John-Stewart
|University of Washington
|Principal Investigator:
|Marie Reilly
|Karolinska Institutet
More Information
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Keywords provided by Medical Research Council:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on September 21, 2017
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Njuguna IN, Ambler G, Reilly M, Ondondo B, Kanyugo M, Lohman-Payne B, Gichuhi C, Borthwick N, Black A, Mehedi SR, Sun J, Maleche-Obimbo E, Chohan B, John-Stewart GC, Jaoko W, Hanke T. PedVacc 002: a phase I/II randomized clinical trial of MVA.HIVA vaccine administered to infants born to human immunodeficiency virus type 1-positive mothers in Nairobi. Vaccine. 2014 Oct 7;32(44):5801-8. doi: 10.1016/j.vaccine.2014.08.034. Epub 2014 Aug 27.
|Responsible Party:
|Tomas Hanke, Medical Research Council, UK
|ClinicalTrials.gov Identifier:
|NCT00981695 History of Changes
|Other Study ID Numbers:
|Study First Received:
|September 21, 2009
|Last Updated:
|June 15, 2011
Keywords provided by Medical Research Council:
HIV preventive vaccine
HIV seronegativity
Additional relevant MeSH terms:
HIV Infections
Lentivirus Infections
Retroviridae Infections
RNA Virus Infections
Virus Diseases
Sexually Transmitted Diseases, Viral
Sexually Transmitted Diseases
Immunologic Deficiency Syndromes
Immune System Diseases
Immunologic Factors
Physiological Effects of Drugs
ClinicalTrials.gov processed this record on September 21, 2017


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A sign you are getting older - your pediatrician retires.
Like many other now 20-somethings in this community, I faithfully went to see "Dr. Winit" for all of my childhood ailments.
As I was growing up, I remember Dr. Winit's kind words made me - and my parents - genuinely feel better about whatever illness I had.
I will never forget how Dr. Winit pronounces my first name and one of several signature phrases he repeatedly told us during our visits - "Enjoy the baby."
As a reporter, there are some interviews that stay with you long after the paper the story was printed on has become a pet cage liner.
I recently interviewed four people I will never forget. And they all, in some small way, have impacted my life and how I will live it.
Several weeks ago, you may have read about two people who quit smoking, Donella Lennox and Bob Shofner. While I don't smoke, I was drawn to the story of how someone was able to quit such an addictive habit.
What do Brenda Allen, Barkley Taylor, Amy Anderson, Lillian Clark, Vangie Ford, Julie Shields, Angie Johnson, Sharon Hoskins, Connie Phillips, Patti Phillips, Pat Hall, Sue Smith and Suzanne Wilson have in common?
They are the only women in Taylor County elected to public office.
So, believe it or not, of the thousands of women in Taylor County, there are but 13 who serve in positions of elected leadership.
Getting a child to read is sometimes difficult, I've been told. Teenagers might rather play video games, go to the movies or spend time with their friends. But a surprising phenomenon has taken over recently ... one that's drawing today's teenagers in droves to book stores. And I have to admit, without any embarrassment at all, that I've been bitten by the phenomenon, too.
It seems today that if you want to make it big, you need only to write a book or screenplay about vampires, and you're set.
Shhh ... I'm cheating, but you can't tell anyone.
The New-Journal sponsors several contests throughout the year that readers can participate in - but those of us who work here, and our families, are not eligible.
And that's only fair.
So, you'll see in the coming weeks an advertisement in the News-Journal about a pet photo contest that is raising money for the News-Journal's Newspapers in Education program.
It's a contest just for CKNJ employees' pets, since we didn't get to participate in the recent contest that was open to the community.
In just a few weeks, a group of energetic Campbellsville and Taylor County high school students will give Central Kentucky News-Journal readers a peek into the world of today's teenagers.
The News-Journal's Teen Editorial Board will soon begin work on its sixth consecutive year of "Insight," our monthly teen page.
You may have noticed something missing from our recent round of economy stories - the minimum wage raise.
Minimum wage recently increased 70 cents to $7.25 per hour, a well-deserved raise I'd say. However, in attempting to include local information about the increase, I ran into brick wall after brick wall.
Unless they are making lots of it, money is one thing few in this town want to talk about. I'm sure it's the same everywhere. Because I work on more than one story at a time, I had to give up pursuing the story and move on.
Some people say newspapers are going the way of the dinosaurs. They're outdated, old and not the way most people get their news these days.
Of course, I'm a little biased on this subject, but I have to argue that these people are woefully misinformed.
Yes, we do hear about the "big" news on television, radio and the internet before we read it in the paper. However, TV and radio tidbits - or even the internet - can't match the in-depth coverage with a different twist that you'll get from a hometown newspaper.
For the last six years I have worked with a non-profit organization providing the patient's voice in improving access to, and reimbursement for, high-quality health care through regulatory and legislative reform at the state and federal levels.
Currently, I am the Kentucky policy liaison for the National Patient Advocate Foundation.
I went back to high school a few weeks ago.
Well, technically, I went to Campbellsville and Taylor County high schools to get some information and photos for stories I was writing.
But while I was there, I couldn't help but think back to my high school days, which were now eight years ago.
First, I went to CHS to see the new marching band. I was excited to hear that the band would be back this year. If you have read my previous columns, you may know that I was a member of the CHS Marching Band for five years.
Copyright © 2017
The Central Kentucky News-Journal is your source for local news, sports, events, and information in Campbellsville, KY and the surrounding area.


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Even if you have been respectful of the market downtrend, the selling is not moving to the point where it is becoming downright disgusted. Once again, we had a slightly positive open that provided false hope for the bulls, and then it was just a steady stream of selling all day. We couldn't even manage a decent intraday bounce. The selling became even worse following the president's press conference.
Unfortunately, there isn't any positive news that can be used as an excuse for buying. The fiscal cliff is far from any resolution, the issues in Europe continue to worsen and hopes aren't very high for the next quarter after a lousy earnings season. Even the Fed has been rendered impotent now that it has used up its QE bullets.
The bull's best argument isn't a very good one. The hope is that we have gone down enough to make stocks a good "value." Unfortunately, market players don't think that way when we are caught in a nasty downtrend. The focus is on growing losses and the idea that a stock may be cheap provides little comfort. We all know that cheap stocks can become even cheaper.
I've been saying for a while that we should respect the trend and just stay out of the way. Let the geniuses in the media make the bold bottom calls. Our job isn't to be sensationalistic but to protect our capital and look to make money when the conditions are in our favor. Those conditions simply don't support buying right now, so why fight it?
The bounce buyers will be looking very hard for some excuse to jump in as we become increasingly extended to the downside. Look for a trade if that is your inclination but don't lose sight of the big picture. We continue to break down and there is no reason other than hope to believe that it is about to end.
Have a good evening. I'll see you tomorrow.


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The Oakland High boys basketball team will play in the Oakland Section championship game for the fourth time in six years after beating visiting Oakland Tech 70-58 in Tuesday's semifinal playoff game.
"This season was definitely a trying season," Wildcats coach Orlando Watkins said. "We had a lot of ups and downs going back to last season dealing with grades and kids not being able to play. This year the kids just came in committed."
Oakland (17-10) will face McClymonds, which beat Skyline in the other semifinal, in the championship game Thursday at 6:30 p.m. at Merritt College. The loser of the title game will play the champion of the Bay Area Charter School Athletic Conference on Saturday at 2 p.m. at Oakland Tech with a berth to the NorCal playoffs on the line.
Oakland Tech (19-9) was looking to reach the championship game for the first time since 2004.
The game was tied after a quarter and remained tied late in the second when the Wildcats went on a 10-0 run to take a 34-24 lead. Oakland held a 37-31 lead at halftime.
The Bulldogs got within 47-43 late in the third, but the Wildcats scored eight straight to end the quarter. Jamaliah Brown had six of those, including a layup at the buzzer to make it 55-43.
Tech scored the first five points of the fourth, but was dealt a blow when Leo Smith picked up his fourth foul. He argued the call and picked up a technical foul, which knocked the first-team All-City pick from the game.
"When Leo picked up that foul, I felt bad for him, but my kids were like, 'Let's pick it up'," Watkins said. "It took us a while to get going, but that ultimately was the separation that won the game for us."
Semaj Horace had 15 points for the Wildcats. Smith led Tech with 16 points.
Girls basketball
Oakland Tech 42, Skyline 35: Ameela Li scored 15 points to rally the host Bulldogs (20-5) over the Titans (17-10) in the Oakland Section semifinals.
Skyline took a 23-17 lead in the third quarter of an ugly game to that point. The teams had 15 turnovers apiece in the first half, which ended with the Titans leading 15-12. Oakland Tech made just 1 of 18 shots from the floor in the second quarter.
"We controlled the tempo," Skyline coach Shawn Hipol said. "We didn't want a high-scoring game. It may be ugly, but that's the way we wanted to play tonight."
The Bulldogs then began making plays. Li had a key 3-point play in a five-point run.
London Robinson scored all six of her points in the fourth quarter and Kelea Pickeral-Dennis had the dagger when she rebounded a missed free throw by Nyela Cade and quickly fed Robinson across the key for a basket with 10 seconds left.
Oakland Tech will play McClymonds in the championship game Thursday at Merritt College at 4:30 p.m.
McClymonds beat Oakland 71-43 in the other semifinal.
— Damin Esper, correspondent