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iPod® Glossary
Ralph Graves is one of Crutchfield's blog editors, and part of the company's social media team. He writes about home audio/video gear, specializing in Apple-related and wireless technologies. Ralph holds a master's degree in music composition, and his works have been released on various labels. He's served as product manager for an independent classical and world music label, produced several recordings, and worked extensively in public broadcasting. Since 1984 he's hosted a weekly classical music program on WTJU, and is also active as a blogger and podcaster.
More from Ralph Graves
Heads up!Welcome to this article from the Crutchfield archives. Have fun reading it, but be aware that the information may be outdated and links may be broken.
Click on a letter below to jump to that section of the glossary.
AAC (Advanced Audio Coding)
A compression format for digital audio. AAC is a newer, more advanced form of compression than the MP3 format. According to some listening tests, AAC files encoded at lower bit rates (like 96 Kbps) sound as good as, or better than, MP3s encoded at higher bit rates (like 128 kbps) despite their notably smaller size.
The current version of the AAC codec was developed as part of the MPEG4 standard. (See our MPEG definition for more on this family of audio/video compression standards.) AAC is the audio format used by Apple in their iTunes® Store. Files may appear on your system with the ".m4a" filename extension.
An accelerometer measures motion and gravitational effects. In an iPod, it's used to detect screen orientation to display a portrait view when the player's held vertically, and a widescreen view when the player's held horizontally. It triggers the shuffle mode in an iPod nano when the player's shaken. The accelerometer in the iPod touch lets you control game play by tilting and tipping the player.
AIFF (Audio Interchange File Format)
An audio format for Macintosh® operating systems commonly used for storing uncompressed, CD-quality sound (similar to WAV files for Windows-based PCs).
Apple Lossless
Apple Lossless Encoding (also known as Apple Lossless, Apple Lossless Audio Codec or ALE) is an audio codec developed by Apple Computer that provides full, uncompressed CD-quality audio in about half the space of the original file.
The term "app" is short for application. Some members of the Apple family of devices, such as the iPhone, iPod Touch, and iPad can be customized with apps purchased from the iTunes Store. An app is usually a small, simple, single-function program, such as a display for weather forecasts, or headline news. Some allow access to online content. Others give the device additional functionality, such as an app that uses the player's accelerometer to turn it into a level. There are currently over 220,000 apps available from the iTunes Store, with more being added daily.
A digital file format for spoken word files purchased from the Audible.com website. Audible files are available at four compression rates — Audible 1, 2, 3, and 4 — with 4 being the least compressed and 1 being the most compressed. iPods are compatible with files encoded in Audible formats 2 through 4.
Auxiliary input
An input that enables you to connect an iPod (or any other audio device) to a receiver. The input can be either minijack or RCA.
Bit rate
With audio compression, the average amount of data required to store one second of music (expressed in kilobits per second, or Kbps). Some codecs like MP3, and AAC allow files to be encoded at different bit rates. Generally, as bit rate decreases, so does the sound quality of the resulting file, as well as the amount of memory required to store it.
Brand-name stereo iPod adapters
An adapter that lets you connect your iPod to your brand-name (or aftermarket) car stereo (vs. a factory stereo iPod adapter). The type of adapter you choose depends upon whether your car stereo includes an auxiliary input. Use our iCarStereosm tool to see the adapters that work with your iPod and your car stereo.
Cassette adapter
This accessory lets you listen to your iPod through the cassette player in your car. It connects to the iPod's headphone output.
Click Wheel
Introduced in 2004, this is the type of control used by iPod nanos and iPod classics (as well as the now discontinued iPod minis). The ingenious Click Wheel incorporates the Menu, Fast-Forward, Rewind, and Play/Pause buttons within the wheel itself, so you can scroll through songs and perform those functions, all from one control.
Cover Flow
Cover Flow is a graphic user interface used for navigation in the iPod touch. The player's touchscreen presents album artwork flowing past in a three-dimensional fashion, as if the albums were swiveling on a rotating rack. Sensors in the touchscreen follow the motion of your finger and go either forward or backwards through the albums accordingly. iTunes has a similar interface that can be operated with your mouse. The iPod classic and iPod nano also have a version of Cover Flow that's operated by the player's Click Wheel.
A cradle for the iPod that connects to a computer for charging the battery and transferring songs and video. Most docks connect to your computer via USB 2.0.
An iPod dock features a multi-pin plug that goes into the base of your player, identical to the one on your player's provided charging cable. You can use the Dock to simplify any kind of connection: the Dock accepts an AC line and can be used as a stand-alone charger. Many docks let you connect your player to your audio/video system through some combination of composite video, S-video, or component video, and stereo minijack or stereo RCA audio connectors.
[Shop our selection of iPod/iPhone docks.]
Dock connector
The port on an iPod that connects it to a Dock, or to a special cable that allows battery charging and music transfer when connected to a computer.
Factory stereo iPod adapters
An adapter that lets you connect your iPod to your factory car stereo. Most factory stereo iPod adapters will charge the iPod and allow you to navigate playlists with your car stereo controls (usually including steering wheel controls). Use our iCarStereosm tool to see the adapters that work with your iPod and your car stereo.
Also known as IEEE 1394 or i.LINK®, FireWire is an extremely fast (up to 400 megabits per second), two-way digital connection used between a computer and an iPod. Newer iPods do not offer FireWire connectivity, but some older generation models accept it in addition to USB.
Flash memory
A form of digital storage developed in 1988 for use in personal computers and PC peripherals, flash memory gets its name because sections of memory cells within the microchip are erased in one simultaneous action, or "flash." Today, flash memory is used in portable MP3 players like the iPod shuffle, as well as in handhelds/PDAs, digital cameras, and for storing digital still pictures in digital camcorders. Because it has no moving parts, flash memory is completely immune to skipping when it's used for audio storage.
A feature of iTunes that creates playlists based on a selected track, generated from music stored in your iTunes library. Genius learns your preferences and how you relate songs by following your listening patterns. It then uses those patterns along with other track information such as artist, genre, etc., to create its playlist.
The more you use iTunes, the more accurately Genius can anticipate your preferences. When you update Genius to the iTunes store, that information is added anonymously to that of everyone else who updated to the iTunes database. This accumulated data allows the Genius feature to make increasingly intelligent recommendations.
This feature is available in the current versions of the iPod nano, iPod touch, iPod classic, and iPhone. Everytime you sync your player, Genius information stored on your device is updated. If you use the Genius button when your player isn't docked, the progam simply creates its playlists from the songs stored on your device.
Hard drive
A hard drive — just like the one inside your computer, only smaller — is the type of memory used by the iPod classic and iPod touch to store music and data. A larger hard drive means that you can save more music, photos, or information to your iPod. Because it has moving parts, a hard drive theoretically can skip while playing music; however, the iPod's 25-minute skip protection minimizes this.
Apple's tablet computer. The iPad features a large 9.7 diagonal touchscreen, with a virtual keyboard. The iPod has built-in Wi-Fi and can be used with AT&T's 3G network for Internet browsing. The iPad can store and play videos, music, and games. It also has an accelerometer to change screen orientation and activate Cover Flow. According to Apple, the iPad bridges the gap between a smart phone and a netbook computer.
Apple's mobile phone. The iPhone uses motion-sensing touchscreen with a virtual keyboard. The iPhone has Internet connectivity, and can be customized with a wide variety of apps. Like the iTouch, the iPhone can store and play music and videos. It uses Cover Flow, has a built-in GPS tracker, and a motion-sensing accelerometer allows for control by tilting the device. The current model is known as the iPhone 4.
iPod classic®
A full-sized version of the iPod equipped with a color LCD, now properly known as the "iPod classic." It can play movies and other videos, display photos, as well as play music and games. The current version available is the third generation model (see our handy chart for more information on iPod generations). It is available in black and white and with 160GB of storage capacity.
iPod nano®
Smaller and more colorful than the iPod classic, the iPod nano is a popular choice for on-the-go listening. The current version available is the sixth generation model (see our handy chart for more information on iPod generations). The iPod nano comes in 8GB and 16GB versions and is available in several colors. The iPod nano runs off of flash memory so it's 100% skip-free.
iPod shuffle®
The iPod shuffle is the tiniest iPod available. Like the nano, it features flash memory for skip-free playback on the go. The current version available is the fourth generation model (see our handy chart for more information on iPod generations). The iPod shuffle is available in either silver or black, with 4GB of memory.
iPod touch®
Modeled on Apple's iPhone, the iPod touch shares many of the same features. It uses a motion-sensing touchscreen rather than a Click Wheel, allowing it to have several virtual buttons for various kinds of control. The screen also allows for fast browsing through Cover Flow.
The iPod touch is Wi-Fi enabled, which lets you browse the Internet, check email, download applications from iTunes, and more when you're at a Wi-Fi hot spot or have a Wi-Fi connection. A motion-sensing accelerometer allows for control by tilting the device. The current iPod touch is the fourth generation model (see our handy chart for more information on iPod generations).
Compatible with both Mac and PC, iTunes is the combination jukebox/music download software that Apple includes with the iPod. It allows easy transfer of music, TV shows, movies, podcasts, games, and other content to your iPod from your computer. It also serves as the source for the iTunes Apps Store, which sells applications for the iPhone and iPod touch.
iTunes tagging
A process that lets you select the song you're listening to on an HD Radio™ station and save it for purchasing at a later time. (See our article on HD Radio to learn how digital HD Radio is different from regular AM and FM.)
To do iTunes tagging, you need a docking iPod, an audio/video component with an HD Radio tuner, iPod dock and "Tag" button; and a local radio station broadcasting an HD Radio signal that has enabled tagging.
As you're listening to a station broadcasting a tag-enabled HD Radio signal, press the "Tag" button when you hear a song you like. The component saves the song information (but not the song itself) in its memory. The information automatically transfers to your iPod when you dock it to the component. The next time you sync your iPod to your computer, your tagged selections appear as a list in iTunes, giving you the option of buying them through the iTunes Store. The purchased tracks are then downloaded to your PC's iTunes library, and copied to your iPod.
MP3 (MPEG-1, Audio Layer 3)
The most popular codec for storing and transferring music. Though it employs a "lossy" compression system which removes frequencies judged to be essentially inaudible, MP3 still manages to deliver near-CD sound quality in a file that's only about a tenth or twelfth the size of a corresponding uncompressed WAV file. When creating an MP3 file, varying amounts of compression can be selected, depending on the desired file size and sound quality. For more info on this topic, see our article on the MP3 format.
One of the most commonly used codecs for storing and transferring video. MPEG-4 compresses audio and video content into manageable file sizes, especially for portable devices such as iPods. MPEG-4 video files usually have an ".mp4" or .m4v" filename extension.
The QuickTime® video format is Apple's proprietary variant of the MPEG-4 codec. Like MPEG-4, QuickTime compresses and audio and video content for more efficient storage on portable devices, such as iPods. QuickTime players come bundled with iTunes. QuickTime video files usually have a ".qt" or ".mov" filename extension.
See iTunes tagging
The touchscreen is currently found on the iPod touch. Initially developed for Apple's iPhone, the touchscreen is actually a multi-touch screen. The screen can process several touch points simultaneously to better accurately interpret hand motion and respond accordingly.
Touch Wheel
Used by earlier generations of the iPod, this control is a wheel that lets you scroll through songs. Unlike the later Click Wheel control, the Touch Wheel does not incorporate the Menu, Fast-Forward, Rewind, and Play/Pause buttons.
USB port
USB (Universal Serial Bus) is a "plug and play" interface between a computer and your iPod (and other devices, including digital cameras, joysticks, keyboards, and printers). The new USB 2.0 standard transmits data at 480 Mbps. That kind of speed makes USB 2.0 suitable for transferring demanding files like full-motion video, etc. Fortunately, all USB 2.0 devices are backwards-compatible with existing USB 1.1 devices.
WAV (Waveform audio format)
A standard audio format for Windows operating systems, often used for storing high-quality, uncompressed sound. WAV files can contain CD-quality (44.1 KHz/16-bit) audio signals. However, CD-quality WAV files require relatively large amounts of memory — roughly 10 MB per minute of music.
Wi-Fi is a wireless protocol developed to allow various kinds of devices to talk to each other. Cellular phones use this kind of connectivity, as do home wireless computer networks. The iPod touch is also one such Wi-Fi enabled device. Many shops, hotels and other businesses offer "open" Wi-Fi hot spots — places where you can access the Internet through your wireless device without needing a password or special software.
Wired FM modulator
A wired FM modulator can connect the iPod to any car stereo, and requires permanent installation. It offers good sound quality, though it does not allow you to charge the iPod's battery or control playback functions through your car stereo. Use our iCarStereosm tool to see wired FM modulators that work with your iPod.
Wireless FM transmitter
A wireless FM transmitter lets you listen to your iPod through your car's FM radio. It offers acceptable sound quality and typically does not require permanent installation. Use our iCarStereosm tool to see wireless transmitters that work with your iPod.


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Recently a report from Stanford University indicated that organic food essentially is not superior to conventionally grown food.
Researchers led by Dena Bravata, MD, MS, from Stanford's Center for Health Policy was published in the Sept. 4 issue of Annals of Internal Medicine, and looked at 237 studies that compared either the health of people who ate organic or conventional foods, or, more commonly, nutrient and contaminant levels in the foods such as bacterial, fungal or pesticide contamination.
In an article on the Stanford's School of Medicine's website, it says, "They did not find strong evidence that organic foods are more nutritious or carry fewer health risks than conventional alternatives, though consumption of organic foods can reduce the risk of pesticide exposure."
Food safety expert Scott Hurd, DVM, PhD, Iowa State University, writes on his food safety blog yesterday that because the authors examined hundreds of studies on the topic, not just a few hand-picked studies, that the meta analysis is a powerful objective method for analyzing a collection of conflicting evidence on a scientific topic.
Where food safety of organic and conventional meat is concerned, Hurd says the authors did not find any significant difference in the amount of food-borne pathogens present in conventional and organic meat. He says, "For example, in chicken 67% of organic samples were contaminated with Campylobacter versus 64% of conventional samples. Salmonella contamination was 35% for organic chicken versus 34% for conventional and E. coli contamination was 65% of organic samples versus 49% of conventional samples."
As far as antibiotic resistance, Hurd says all types mea t have the potential to have antibiotic resistant bacteria. But to cause harm to human health, even antibiotic resistant pathogens on meat have a long journey to make including pathogen survival during processing and cooking, ingestion of the resistant pathogens, and a resulting illness requiring antibiotics. Hurd says, "The harm would only result if all of these things happened and the bacteria did not respond to the antibiotic therapy."
The bottom line, concludes Hurd: "Today's modern farmer is not going to wipe out the human race."
To read Hurd's blog, click here.

subset: commoncrawl


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A Vallejo father and son died in a Thursday morning crash on Highway 101 north of Laytonville. The driver was wearing a seatbelt and escaped with minor injuries.
Investigators found a variety of weapons and equipment including a map detailing directions from Vallejo to Shelter Cove inside the crashed vehicle.
The driver Domonic Troy Quilici, 20, of Crockett, was arrested on suspicion of vehicular manslaughter after being released from Frank R. Howard Memorial Hospital for treatment of his injuries.
Quilici was driving a 2001 Infinity QX4 northbound on Highway 101 at 8:15 a.m. Thursday near Cummings, when for unknown reasons it left the eastern roadway edge.
The car smashed into an embankment and then overturned a number of times before coming to rest on the driver's side near the eastern shoulder, according to the California Highway Patrol.
The passengers, Greg Saul Dodson, 44, and Vincent Jay Dodson, 21, both of Vallejo were not wearing seatbelts and were ejected from the out-of-control vehicle, say police. Vincent was pronounced dead at the scene. His father, Greg, was flown to Mercy Medical Center in Redding and later succumbed to his injuries.
Drugs or alcohol are not believed to be involved in the crash, say police.
During the investigation into the crash, police discovered three loaded firearms in the car, including two believed to be stolen. In addition to the firearms, police recovered two bulletproof vests, illegal explosive devices, a tactical police baton, duct tape and a ski mask. A printed driving map giving direction from Vallejo to Shelter Cove also was found in the car.
CHP now suspects the three men were on their way to conduct a home invasion robbery or a marijuana sale rip-off in Shelter Cove. Police do not have an address for the planned robbery.
Anyone with information about this incident is being asked to phone the CHP office in Garberville at 923-2155.


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A schedule of events happening around Kentucky.
December 2009
- Featured: Southern Lights, Lexington , November 20-December 31 Even the Thoroughbreds who live at the Kentucky Horse Park have a thoroughly good time during this holiday celebration of light displays, musical performances, pony rides, and arts and crafts shows. southernlightsky.org or 859-255-5727
- Featured: Hollydays Art And Gift Market, Louisville, December 4-6 Find that last-minute Christmas gift during this annual Junior League of Louisville event at the Mellwood Arts & Entertainment Center. juniorleaguelouisville.org or 502-637-5415
November 2009
- Featured: Kentucky Book Fair, Frankfort, November 7. Literature lovers from across the Bluegrass State converge on the capital city for this event featuring 150 authors. 502-564-8300, ext. 297
- Featured: Lexington Farmer's Market, Lexington, November 7, 14, 21, and 28. Fall brings pumpkins and more to Cheapside Park.
- Featured: Winter Trade Days at the Fort, Richmond, November 28-29. Pretend you're Daniel Boone as you buy from 18th-century-style craftsmen at Fort Boonesborough State Park.
Harry Pickens Trio, Crestwood, Yew Dell Gardens, November 19. 502-241-4788


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My Christmas Wish List (part one)
With the holidays approaching, it is becoming time to think about giving gifts to your loved ones. It is always appreciated when each family member creates a wish list so that I am able to give gifts that they really want. So, I decided to sit down at think about the top items on my scrapbook wish list. Thought that I would share my list with you. Epson R1800 large-format printer. I've been wanting this for quiet a while, but the large price tag is holding me back. I have read many reviews and almost everyone who had this print … Continue reading


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Peer-Reviewed Publications
Found 8 resultsTitle
Filters: First Letter Of Last Name is F and Author is L Fleisher [Clear All Filters]
Build it, and will they come? Unexpected findings from a study on a Web-based intervention to improve colorectal cancer screening." J Health Commun. 2012;17(1):41-53."
Application of best practice approaches for designing decision support tools: The preparatory education about clinical trials (PRE-ACT) study." Patient Educ Couns. 2014;96(1):63-71."
Implementation of a Theory-based, Non-clinical Patient Navigator Program to Address Barriers in an Urban Cancer Center Setting." Journal of Oncology Navigation and Survivorship. 2012;3(3)."
Best Practices in Culturally Appropriate Education Approaches." Ethnicity,Health, and Well-Being . 2013."
Relationship of Internet health information use with patient behavior and self-efficacy: experiences of newly diagnosed cancer patients who contact the National Cancer Institute's Cancer Information Service." J Health Commun. 2006;11(2):219-36."
Development and utilization of complementary communication channels for treatment decision making and survivorship issues among cancer patients: The CIS Research Consortium Experience." Internet Interv. 2015;2(4):392-398."
Using health communication best practices to develop a web-based provider-patient communication aid: the CONNECT study." Patient Educ Couns. 2008;71(3):378-87."


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Autoimmunity in Inner Ear Disease
This study has been terminated.
National Institute on Deafness and Other Communication Disorders (NIDCD)
Information provided by:
National Institute on Deafness and Other Communication Disorders (NIDCD)
ClinicalTrials.gov Identifier:
First received: November 2, 1999
Last updated: April 21, 2006
Last verified: April 2006
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
The purpose of this study is to determine whether prednisone, methotrexate, and cyclophosphamide are effective in the treatment of rapidly progressive sensorineural hearing loss in both ears. This condition is called autoimmune inner ear disease (AIED), because it is thought that the hearing loss is triggered by an autoimmune process. Treatment attempts to suppress or control this process with powerful anti-inflammatory drugs. This is a Phase III, outpatient study. All study participants will be assigned to one of four different groups testing the experimental use of drugs. The study is scheduled to run for 18 months, with a minimum of 11 visits per participant.
|Hearing Loss, Sensorineural
|Drug: Corticosteroids Drug: Methotrexate
|Phase 3
|Study Type:
|Study Design:
|Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double
Primary Purpose: Treatment
Resource links provided by NLM:
Genetics Home Reference related topics: nonsyndromic hearing loss
MedlinePlus related topics: Ear Disorders Hearing Disorders and Deafness
Drug Information available for: MethotrexateU.S. FDA Resources
Further study details as provided by National Institute on Deafness and Other Communication Disorders (NIDCD):
|Ages Eligible for Study:
|18 Years to 70 Years (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Have sensorineural (nerve/inner ear) hearing loss of at least 30 dB in each ear, which has rapidly progressed.
- Are in good general health.
- Are sterile or use contraception (if a woman of child-bearing age).
- Are able to speak and understand English or Spanish.
Exclusion Criteria:
- Have had any previous reaction to prednisone, or history of psychiatric reaction to corticosteroids.
- Have used corticosteroids for more than 30 days within the past 90 days. Patients who have been off corticosteroids for at least 30 days may be eligible.
- Have any significant heart, lung, digestive, blood, or neurologic disorders.
- Have tuberculosis (TB), brittle or unstable insulin-dependent diabetes mellitus, active malignancy or prior chemotherapy, pancreatitis, active peptic ulcer disease, kidney failure, history of shingles, or known (other) autoimmune disease.
- Have had a positive test for HIV, hepatitis C or B.
- Have any type of middle ear disorder.
- Are breast-feeding or pregnant.
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00000361
Please refer to this study by its ClinicalTrials.gov identifier: NCT00000361
|United States, California
|House Ear Institute
|Los Angeles, California, United States, 90057
|UCSD Medical Center
|San Diego, California, United States, 92103-8895
|United States, Iowa
|Univ of Iowa Hosp and Clinic
|Iowa City, Iowa, United States, 52242-1078
|United States, Maryland
|Johns Hopkins Univ
|Baltimore, Maryland, United States, 21287-0008
|United States, Massachusetts
|Massachusetts Eye and Ear Infirmary
|Boston, Massachusetts, United States, 02114
|United States, Michigan
|Univ of Michigan
|Ann Arbor, Michigan, United States, 48109-0005
|United States, New York
|New York University
|New York, New York, United States
|United States, Ohio
|Cleveland Clinic Foundation
|Cleveland, Ohio, United States, 44195-5245
|United States, Texas
|University of Texas, Southwestern Medical Center at Dallas
|Dallas, Texas, United States
Sponsors and Collaborators
National Institute on Deafness and Other Communication Disorders (NIDCD)
|Study Chair:
|Dr. Jeffrey Harris
|Principal Investigator:
|Dr. Patrick Brookhouser
More Information
Keywords provided by National Institute on Deafness and Other Communication Disorders (NIDCD):
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on September 25, 2017
|ClinicalTrials.gov Identifier:
|NCT00000361 History of Changes
|Other Study ID Numbers:
U01DC003209 ( U.S. NIH Grant/Contract )
|Study First Received:
|November 2, 1999
|Last Updated:
|April 21, 2006
Keywords provided by National Institute on Deafness and Other Communication Disorders (NIDCD):
Autoimmune Diseases
Labyrinth Diseases
Additional relevant MeSH terms:
Hearing Disorders
Ear Diseases
Otorhinolaryngologic Diseases
Sensation Disorders
Nervous System Diseases
Hearing Loss
Hearing Loss, Sensorineural
Neurologic Manifestations
Signs and Symptoms
Abortifacient Agents, Nonsteroidal
Abortifacient Agents
Reproductive Control Agents
Physiological Effects of Drugs
Antimetabolites, Antineoplastic
Molecular Mechanisms of Pharmacological Action
Antineoplastic Agents
Dermatologic Agents
Enzyme Inhibitors
Folic Acid Antagonists
Immunosuppressive Agents
Immunologic Factors
Antirheumatic Agents
Nucleic Acid Synthesis Inhibitors
ClinicalTrials.gov processed this record on September 25, 2017


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The intentions of the Hunger-Free Kids Act of 2010, championed by First Lady Michelle Obama, may provide healthier school lunches in an effort to combat childhood obesity, but students are voicing their literal distaste for the new school food.
For students in one rural Kentucky county – and their parents – the food "tastes lime vomit."
According to the Harlan Daily Enterprise, Harlan County parents, students and school board members are speaking against the healthier food.
"Kids can't learn when they're hungry!" parents yelled at the special school board meeting last week.
Milk was brought up several times in the meeting. Jack Miniard, director of school and community nutrition, explained that the fat content of the milk served in the country's schools were one percent or skim. Non-fat flavored milk varities were still on the menu.
However, Miniard said he would conduct a "taste test" of the milk with students and report back to the board with results. Read more here.
Obama admitted that kids and parents aren't 100 percent on board with the taste of the healthier school lunches in an interview with Parade magazine.
"Change is hard—it's as simple as that," Obama told Parade. "You start making tweaks to something that has been a mainstay and you're going to get some backlash, particularly from kids. We as adults can't be shortsighted."
According to Red Alert Politics, several school districts nationwide have even decided to completely opt-out of the program because students have refused to eat the less-palatable foods mandate by the act. Click here for more.
Last year, a group of Kansas students released a music video parody to protest the calorie maximums of the Hunger-Free Kids Act of 2010.
"Active teens require between 2,000 – 5,000 calories a day to energy and growth needs," text at the beginning of the video states. "School lunch policy mandates all teens receive only 750-850 calories per lunch."
Click the video to the right to see the full clip.


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2017 Reference Guide: Page 39


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The 49-metre ribbon is being used at the Premier League clash on Saturday to raise awareness of World AIDS Day 2012 and Standard Chartered's Living with HIV programme
Liverpool will unveil the world's biggest AIDS ribbon during half-time of their match against Southampton on Saturday to raise awareness for World AIDS Day 2012 and Standard Chartered's Living with HIV programme.
The ribbon stretches to 49 metres and will be rolled out across the pitch at Anfield with help from staff at Standard Chartered and the HIV/AIDS charity AVERT.
The ribbon was made in India and is recognised as the largest in the world by Guinness World Records, and will be making its first appearance in the UK at the match.
Liverpool's managing director Ian Ayre said: "Living with HIV is an important cause, and one which the club is proud to support.
"When an individual wears a red ribbon they are demonstrating that they have joined the global fight against HIV, so we are delighted to be able to use the Anfield pitch to display the ribbon and raise awareness for HIV and AIDS."
Mark Devadason of Standard Chartered described the match as the "perfect opportunity" to unveil the banner, highlighting it as an important moment in the battle to raise awareness of HIV and AIDS.
"Liverpool is scheduled to play Southampton on World AIDS Day making it the perfect opportunity to display the red ribbon and reinforce our commitment to the global fight against HIV.
He continued: "Our thanks go out to both Liverpool and AVERT who have made this activity possible, and enabled us to show our solidarity with those living with HIV and commemorate those who have died from the illness."
Living with HIV is Standard Chartered's global HIV and AIDS education programme, which seeks to inform people across the globe about preventative measures and treatments for the viruses.


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Mitsubishi Aircraft scored an enormous marketing coup last month when it signed its first customer outside Japan for the 78- to 92-seat MRJ. The letter of intent, signed by St. Louis-based Trans States Holdings, owner of Trans States Airlines and GoJet, calls for a firm order for 50 airplanes, along with options for another 50. The parties haven't come to an agreement yet on the mix of aircraft sizes, nor has Trans States entered a service contract under which to fly the airplanes with a major airline, however. Apart from the Trans States LOI, Mitsubishi's order book shows firm orders for 15 MRJs and options for another 10 from Japanese airline ANA.
"We believe the MRJ is a game-changing regional jet that takes into account the environment, as well as passenger and airline needs," said Trans States president Rick Leach. "The MRJ will reduce fuel consumption, noise and NOx emissions–this means savings on operating costs. By combining the largest cabin in the regional
jet market with the innovative seat design and quiet cabin, we will be able to offer our passengers the best comfort of any regional jet."
Mitsubishi announced in September that it would delay first flight of the 92-seat MRJ90 by as much as six months, from late 2011 to the second quarter of 2012, to accommodate changes to the design of the cabin and the wing box. MJet now expects to deliver the first MRJ90 during the first quarter of 2014. Development of the 78-seat MRJ70 trails that of its larger sibling by roughly a year.
MJet has decided on an aluminum, rather than composite, wing box, ostensibly easing the manufacture of an optimal wing structure, according to the company.
The aluminum box will allow for a shorter lead time for structural changes and allow designers to more easily optimize the wings to match the attributes of each member of the MRJ series.
According to MJet, it has finalized the configuration of the MRJ, placing it on a path toward completion of critical design review and design freeze "in the coming months." The company claims the new configuration incorporates a number of "significant" improvements resulting from discussions with and feedback from potential customers.
The improvements include increasing the height of the cabin by 1.5 inches, raising head clearance by the same amount and increasing space in the overhead bin by 12 percent. The new configuration will allow passengers to store large-size roller bags in the overhead compartments. Meanwhile, the company has combined the forward and aft cargo compartments into a single 644-cu-ft aft compartment, resulting in the same amount of space but making baggage handling simpler, with the added bonus of improved stacking efficiency.
Mitsubishi has now begun to consider a 100-seat version of the airplane, contingent on enough market demand to trigger a full-scale launch. As late as the Regional Airline Association convention, held May 18 to 21 in Salt Lake City, Mitsubishi Aircraft executive v-p Junichi Miyakawa dismissed the idea of a stretched variant due to the regulatory requirements that call for a third flight attendant in airplanes that carry 100 seats.


text:
The next meeting of the Bratton History Association will take place on Sunday, May 18 at the Church Institute from 4pm.
The speaker will be Margaret Miller and the subject will be memories of her life in Wiltshire.
For anyone interested in more information on the event or the association in general, contact Mo Maclean on 01380 830221.


text:
Walled Lake Schools' student choirs invite the community to the "Name of Love" benefit concert at 7 p.m. Tuesday, Feb. 26 at Walled Lake Northern High School, 6000 Bogie Lake Road in Commerce.
This is a benefit concert for the victims of Hurricane Sandy with a free will offering at the end of the show to be donated to the Red Cross Relief effort.
The eighth-grade choirs from Clifford Smart, Sarah Banks, Geisler and Walnut Creek Middle Schools will perform with the high school choirs from Walled Lake Central, Northern and Western High Schools for some of the selections.
The three high school directors, Mary Rashid, Mike Peterson and Greg Cleveland, felt the need to set up a benefit concert for the hurricane victims.
A free will offering will be taken after the concert. Anyone wishing to donate may send their donation to Walled Lake Central High School, Mary Rashid 1600 Oakley Park Road, Walled Lake 48390. Checks may be made to W.L. Central HS or The American Red Cross.
For more information, contact Judy Evola at email@example.com.


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Yes, and that is on the coach. The coach we are *****ing about.This quote is hidden because you are ignoring this member. Show Quote
Slight tangent--how hurt was Hulls down the stretch last year?
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Yes, and that is on the coach. The coach we are *****ing about.
Slight tangent--how hurt was Hulls down the stretch last year?
"Everything else" which I consider including practice, has question marks.
So the question is, can you find a better candidate with an offense that makes sense, with recruiting power and with all those non-gametime intangibles? If so, sure, put his name on a list. IU isn't buying out Crean any time soon, but I'm game to discuss.
I just imagine, by the time IU gets to a point where Crean could realistically be on the way out, he won't be because this young team will have matured into a championship-caliber one.
I'm almost the opposite. I hate his in-game adjustments, his nonsensical substitution patterns, his half court offense (you aren't going to get out and run on everybody, all the time, after all), his use of timeouts, and his adjustments in general (assuming he makes any). Off the court, I don't know, the players seem to work hard, they certainly graduate, stay out of trouble, etc. His recruiting is a bit maddening with his tendency to throw out 100 scholarship offers a year, accepting commitments from freshmen/sophomores, and his love affair with wings who do more or less the same thing. We've already been over his insane practices.
He isn't going anywhere now. We all know that. He would have the miss the NCAAs this year (looking like a strong bet, but they still have an outside chance) and lose Vonleh; they will have nothing in the way of post players next season. Rumblings are afoot that IU is going to lose two more players to transfer, with Hanner Perea possibly being one of them. Just like this year's team had a major weakness as far as having no shooters outside of Yogi, next year's team is going to get pounded inside and on the glass unless Crean can pull a recruiting miracle. So next year it's possible we miss the NCAAs again. After that, I would think his seat would be pretty warm heading into the 2015-2016 season.
OK, I'm finally on the bandwagon. Tom Crean needs to go. His situational lineups are embarrassing, and his team is just plain dumb. He coached them out of a win today.
Hahaha, let this be the final nail in the coffin for Tom Crean.
Can we fire Crean already.
**** this team. No ****ing heart. Terrible ****ing coach. I'm done.
What an absolute joke.
Counting down the days untill DJ Augustin's contract expires.
That's the nail in the coffin. No tournament for us.
Oh well Mr Crean's seat just got a hell of a lot warmer.
Counting down the days untill DJ Augustin's contract expires.
This reminds me of the Mike Davis years when I would watch IU and take solace in every loss by telling myself, "We are now that much closer to firing this imbecile." Sadly, Crean's seat is room temperature.
Oh god don't go there.
Seeing 2-3 zone every game was bad enough now we're going to see a lot more press as well.
Saturday is going to be a nightmare. Can Crean just stay home?
missed most of the game but the last minute. this team is in a fight to make the nit. simply no shot at ncaa this year. the only way that happens is if every other team gets food poisoning in the big10 tourney and even then, it is an outside shot at best.
if vonleh declares- expect to see something along a repeat of this year for next season as we will have no interior scoring or defense.
Peegs board is going absolutely berzerk. Crean may have lost some of his disciples tonight...
he ALMOST coached them out of the Wisconsin win too. i remember he subbed out vonleh near the end and he wasn't in foul trouble or anything- just a crean-type substitution and put in the substantially smaller etherington and that probably just about made bo ryan's day as he saw a stupid substitution and promptly attacked and scored on it. it was nice to see the crowd wasn't too pleased about it and they booed crean for it. and i heard boos again tonight at the end.
i am beginning to believe that the crowd is getting a bit tired of tom.
I hope the crowd is growing tired of it. Crean can thank DWade for his hiring. Without one of the NBA's greatest players stopping at Marquette on his way to the NBA I wonder if he could've even sustained his job at Marquette? He's really just not very good. Especially for a top rung program. Or one trying to get back to the top rung.
Like I said, we should've seen this coming. The signs were there early on but the decimated roster gave him an excuse. And the recruiting successes that started flowing in moved the needle on the record. But in hindsight I'm not sure any of Crean's IU will ever be accused of being over-achievers. And much of that is on coaching. Ill prepared for games, a bad offense, unable to adjust, and with maddening substitutions further creating problems.
Crean has peaked. Now the flaws are there for all to see. It's not going to get better. It's only going to make recruiting harder and create questions among team members from here on out. When it's over it's over. IU risks a quick fall and major setback if Crean continues too long. And 'too long' isn't going to be very long.... IMHO
Nuntius was right for a while. I was wrong for a while. But ultimately I was right and Frank Vogel has been let go.
"A player who makes a team great is more valuable than a great player. Losing yourself in the group, for the good of the group, thats teamwork."
-John Wooden
Noah Vonleh had 3 FG attempts. That alone is a fireable offense.
"I had to take her down like Chris Brown."
-Lance Stephenson
Losing at home to Penn State and Northwestern in the same year ....just sigh. I thought we were past this type of ****.
Also, some of Crean's quotes from last night after the game are so hilariously obtuse and ironic that I almost have to wonder if he did it intentionally.
Does anyone else find themselves watching our half court offense and feel like it is fundamentally the same **** that Mike Davis used here? We get under the 3 point line pretty much never. It is embarrassing.
Sampson may have been a lying cheat, but at least I could watch his team play basketball without wanting to cut my eyes out. Why can't we ever find a balance?
Also, I'm tired of the we are young excuses. This team has 2 top 20 5 star recruits at arguably the two most important positions in college basketball (point guard and post play), the rest of the roster is stacked with very high potential 4 stars. Teams have and do win with significantly less at a young age and on a regular basis.
Unfortunantly Crean will be stuck at IU for a long time. Buyout too expensive at this point.
If you really want to laugh, read his twitter account. After the professor from Gilligan's Island and Rueben from the partridge family died, he said they made those shows go. LOL. How did we end up with such a genius?


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Accommodation in Treuchtlingen
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Are you looking for a hotel, guesthouse, bed and breakfast or a holiday apartment to rent?
If so, then you have come to the right place! We have a selection of accommodation options to suit every budget and taste. You can also find all the details and contact information for all the accommodation options in our current brochure, which is available for download here.
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Campsite and boat mooring
A campsite for tents only and boat mooring site for cyclists, walkers and boating tourists located on Kanalstrasse. Individual travellers, families and groups are all welcome!
For groups, please book in advance.
Address: Kanalstrasse (approx. 150 metres behind the Lidl supermarket)
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Tuesday November 25, 2008 9:56 pm
T-Mobile's Motorola ZN5 Going For Free This Weekend
Posted by Patrick Phelps Categories: Cameras, Cell Phones, Hot Deals
Remember Motorola's 5-megapixel ZN5 cameraphone? It seems that T-Mobile REALLY wants you to have one: they just announced that beginning on Black Friday and going through Sunday they'll be offering a $100 mail-in rebate on the $99 phone (with a two-year contract). Free is an amazing price considering you're getting a 5-megapixel autofocus quad-band phone which includes a xenon flash and WiFi capability. We're pretty sure these guys will fly off the shelves – at least for one weekend.
Read More | FierceWireless
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Yes! Yes! Yes! The Raw Review (#YYYTRR)
by, 07-24-2012 at 07:02 AM (8519 Views)
1,000 episodes and hundreds of shocking moments, and Raw 1000 was no different.
To put it simply, last night's Raw was amazing. I refuse to go as far as saying it was the WrestleMania of Raw's, like Michael Cole, but pretty much everything that happened lived up to the hype. Give or take the fact that World Heavyweight Champion Sheamus was put into a six-man tag team match rather than given something worthwhile, and that Chris Jericho and Dolph Ziggler's rivalry was progressed in a bizarre way (they're already rivals, why would they team up?), and you have a truly great episode of Raw.
Punk turned heel in epic fashion, The Miz became WWE's 21st Triple Crown champion, and The Rock will be back at the Royal Rumble. That's not even it, Triple H and Brock Lesnar will go at it at SummerSlam (much to nobody's surprise) in a match which looks like it could be more brutal than Cena/Lesnar was at Extreme Rules, and a multitude of legends made deserved appearances.
The only reservation I have is the lack of beer-swilling and ass-kicking from a certain rattlesnake.
CM Punk's revolution comes full circle
A CM Punk heel turn is something I personally love, and the fact that he did it by turning on John Cena and The Rock just makes it better.
The pieces have been in place for this for just over a year, when CM Punk delivered his infamous pipe bomb. He basically pointed out that Cena and Rock were in the spotlight whilst he, the best in the world, had to sit in the background and just accept it. The fact is that CM Punk has carried WWE for me (with the help of Daniel Bryan and Chris Jericho) over the past year, whilst John Cena has continually been involved in pointless angles with no surprises. It now makes sense why Punk has had to be the warm-up for the John Cena show month after month – it gives Punk motivation to snap and turn on the fans.
It is just a brilliantly orchestrated angle which WWE has played out here. The assumption that Punk's revolution had been forgotten (like so many of WWE's efforts in recent years) once Punk held the title for 250 days could not have just been in my head, and the fact that they're effectively building an 18 month story is impressive for today's WWE.
On another note, The Rock can sell a flying clothesline and the GTS better than so many others. Viva la revolution!
Bryan's wedding blues, Rock to challenge at Royal Rumble
After the inevitable failed wedding was over with, we had a new Raw GM in the crazy AJ (should be interesting to see what happens to Bryan over the next few months) and the makings of a great Rocky promo after Bryan's claim that he is the "greatest WWE superstar ever" – he's pretty damn good, but the greatest ever is a slight overstatement. After proceeding to call Bryan every Lord of the Rings reference he could, Rocky decided to set in motion a potential feud of the year.
He will challenge the WWE Champion at Royal Rumble, and by the looks of it that man will now most certainly be CM Punk. Knowing that The Rock is going to be away for the next 5/6 months gives Punk the chance to unleash his inner heel – something which we all know he excels at. He can make the WWE Championship mean more than he already has, and become the most hated heel since JBL cheated to retain the same title for 10 months (his Clothesline from Hell on Slater was epic, btw).
And then you have the return of The Rock. You can hate the fact that he shows up every now and again and somehow gets a WWE Championship match without a single match, but the fact is he is always going to cause fans (including myself) to erupt. He oozes charisma and so does Punk, and with the pieces in place for a great heel/face encounter the promos between these two are likely to be amazing. It helps that they can both 'go' in the ring too.
The only sad thing is that their match at Royal Rumble will likely lead to Rocky winning (thus ending what would be a 427 day (or thereabout) title reign) and facing Cena at WrestleMania for a second time, whilst Punk could potentially go on to face Stone Cold Steve Austin at the same event. To be clear, the sad part is that The Rock would be the one to end Punk's title reign, rather than somebody progressive like Daniel Bryan.
Either way, I'm quite excited for Punk's heel Championship run.
In other news…
Mr. McMahon thanks the WWE Universe – this was a fitting way to open Raw 1000, I just wish he'd stuck around for the DX reunion.
DX reunites, Damien Sandow gets the classic DX treatment – of the many mark-out moments last night, this was easily the best one. It was especially funny to see HBK and Billy Gunn fighting over who owns the DX catchphrases.
World Heavyweight Champion Sheamus, Rey Mysterio & Sin Cara def. Chris Jericho, Dolph Ziggler & Alberto Del Rio – I'm not entirely sure why, on a 3-hour show, they needed to put six superstars in a quick match. What was more bizarre was the way they decided to further the Jericho/Ziggler feud (they're already rivals, why make them team up?). I'd rather have seen Dolph interrupt a classic Jericho promo and accuse Y2J of rehashing old material.
Brodus Clay def. Jack Swagger – this match took all of 10 seconds, and even the Dude Love dancing part was disappointing. The Funkasaurus gimmick is tired and boring, change it.
The Miz becomes WWE's 21st Triple Crown champion – finally Christian's unnecessary Intercontinental Championship reign is over. I like him, but he doesn't need a midcard title when the WHC is open to new challengers. The Miz is finally on his way back up, awesome!
Brock Lesnar vs. Triple H set for SummerSlam – not remotely surprising that this match is happening, but at least it was a good segment. The potential brutality of this match actually has me looking forward to it. Also, the return of mega-MILF Stephanie McMahon was welcome.
Lita def. Heath Slater – I loved seeing Lita, but what was better was the sound of the APA's music hitting. A true mark out moment for this fan.
Daniel Bryan vs. Charlie Sheen? – after a series of Skype interactions with Sheen throughout the night from Cole, he seemed to have no sympathy for Bryan being stood up and simply told him to "man up". As much as I enjoyed his presence on Raw, I don't want to see Bryan's push wasted on a meaningless celebrity feud.
The return of the Brothers of Destruction – it was fitting that Undertaker returned for Raw 1000 considering he main evented the very first episode. It was no DX or APA moment for me, but it was nice to see.
Like I said, I loved this episode of Raw.
It was a great way to celebrate 1,000 episodes, but I hope Bryan isn't lost in the fray now and they keep his angle with AJ going. I also hope they can do better with the matches in the permanent 3-hour timeslot – the WWE Championship match lasted all of 10 minutes and was all in the overrun. When you have three hours you can fit a decent 30-minute match onto the card (especially when 5 minutes was just Santino and Hornswoggle handing out WWE's latest toy).
It wasn't perfect, but it was pretty damn good. The Punk heel turn made it for me, and AJ as GM should be an interesting change of events.
I just wish America would stop pissing about with their commercial times and give us 10 minutes without a break. Seriously, sort it out!
Thanks for reading, and for more of my views follow me on Twitter (@SpringerAJ) and give me your feedback with #YYYTRR.


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NEW YORK — On Sept. 27, Gap will debut a limited-edition collection for men designed by GQ's six best new menswear designers in America for 2012.
"From the very early stages of the design process, we knew this collection was going to be something our customers were drawn to," said Mark Breitbard, head of merchandising for Gap North America. "These designers are shaping the future of menswear, and it's an honor to bring their distinct visions to life in a way that complements Gap's casual American point of view."
With price points starting at $20 for essential items such as boxer briefs and ranging up to $348 for more indulgent pieces like a leather bomber jacket, the collection is available at select Gap stores worldwide and online at Gap.com. The collection will include hats, belts, knit ties and scarves; graphic tees, fleece hoodies, oxfords and mohair cardigans; chinos, cargo pants, wool trousers and denim; and blazers, wool peacoats, parkas and leather bombers.
The six designers and the pieces from their Gap-exclusive capsule collections will be featured in a special fourteen-page advertising insert in the October 2012 issue of GQ. They include:
Johan Lindeberg's BLK DNM;
Ian Velardi;
Mark McNairy New Amsterdam;
Ariel and Shimon Ovadia, of Ovadia & Sons;
Saturdays NYC, founded by Morgan Collett, Josh Rosen, and Colin Tunstall; and
Todd Snyder.


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So I've been pretty glued to this forum for the past month or so, really trying to figure out how to improve at this game that I've fallen in love with playing. I'm about 4 months in at this point and play 2-3 time per week and get another 1-2 hours of practice in per week (more as the days start getting longer and I have daylight). After digging through dozens of threads on this forum I found something that was a bit eye opening to me - a post by Blake_T (big surprise right) in a discussion of the teeRex. He described two players, both into the game both of which took very different paths through disc selection. I see a lot of the Player A is this situation in the guys I play with: they've all been playing about two years longer than I have and interestingly enough, 2 out of 3 of them throw almost exclusively forehand. As I was moving through the early stages of my game it was all about how fast the driver was - here throw this nuke, it'll go further - here try a destroyer, etc, etc. And I fell into this, especially having a decent amount of success with a blizzard katana that a friend didn't want - instantly my 220 drives were going 260 and I was pretty hooked. The idea of throwing a midrange is still pretty much out of the question for most of the guys I play with so it took a bit before I was introduced the vast amount of discs available. This eventually lead me here... So what I've decided to do is become the player "b" in Blake_T's made up scenario. I've accumulated roughly 30 discs since starting but I've parred everything in my bag down to the following, hoping to improve and find a way to "disc up" in the coming months/years. Right now I'm committed to keeping a bag fairly similar to what I threw for 36 holes today:
171 Champion TeeBird (bought used but not overly beat in)
??? Champion Leopard (again bought used and rather beat in - can barely make out that it was a leopard and haven't found a way to weigh the disc yet, I'm thinking it is 165-170 but not 100% sure)
150 Champion Leopard (more on this later...)
171 Roc 3
172 Z Buzzz
173 Proton Ion
175 SS Wizard
175 SSS Warlock
This is my thought process. Yes, I can throw my Beast, Valkyrie, Orion LS, Katana, and Opto Saint further than my TeeBird, but not what I believe to be optimal for the disc themselves. On a good drive, I can make the TeeBird "S curve" out to about 275-280. The older leopard about the same. The lightweight Leopard I almost always turn over with OAT (this, I think is a sign of me trying to kill the disc(??) - even when I thought I was throwing on a hyzer the disc came out as a straight anny on one of the holes I played today)
My goal is to learn to try and shape and control as much as I can and build up distance and slowly move back into the valks, orions, wraiths, etc. as my game improves. I might make some tweeks here and there, I've never thrown an XD, gazelle, cyclone, comet - all of which have been brought up in posts I've read.
I'm initially thinking, and after 36 holes today have a little to go with that the bag right now plays like this:
TeeBird (main driver for longer holes, best disc dealing with the wind, continue to build distance)
Leopard (develop a hyzer flip with the disc and see what happens, continue to build distance)
Roc3 (drive on shorter holes (<250ft) nice shot shaping disc, likes to do what I expect it to do, can stand still this disc to about 160)
Buzzz (for tight windows/hallways/tunnels - this disc is the straightest disc in my bag, slightly shorter than the roc3)
SS Wizard (upshot putter 100 ft and in)
Ion (inside the circle putter)
SSS Warlock (I like this for stall putts, it just will land soft)
the big thing I learned today was that the 60-80 ft shot is damn hard for me to figure out. I know it is a putter and it's not a full putter at all, or a standstill with a reach back - these go more in the 100-110 ft range for me) and I can't seem to straddle putt out this far at all, really anything outside of 50 ft I can't seem to straddle putt at all right now) Anyone have ideas on this shot? Kindof reminds me of the 60 yard shot in ball golf - uncomfortable...
So essentially I'm going to try my damnedest to develop my game this way. Have several shots in the bag beyond just bombing something out there.
A quick question - there seems to be a lot of talk about buying low end plastic to really learn how discs fly. Living in the desert eats these discs alive where as the champ/star plastics really hold up to knocking into trees and landing on desert rock all day long... Am I hurting my development running out champ plastic discs???
Anyone build a game like this? Thoughts??? Pros/cons? Suggestions?


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Summit Up 10-28-12: The legend of Lady Silverheels, part two
October 27, 2012
Good morning and welcome to Summit Up, the world's only daily column that's picking up right where we left off in the legend of Lady Silverheels in this special Halloween edition.
Yesterday the SU Committee of Halloween Terror introduced Lady Silverheels, Summit County's most well known beneficiary to the miners at the turn of the century. When we left off, she had become infected herself after attending to miners with smallpox and wandered off into the woods never to be seen again.
Whether correlated or not, upon her disappearance, Summit County was relieved of the presence of a shadowy, city character that had been hanging around collecting the hair from fallen miners (weird, we know).
Much speculation arose after the disappearance of the fair Lady Silverheels. How was she connected to the frightening man? Why did she wander off? And why would she want to take care of the miners in the first place? It seems to us that she must have had some kind of death wish anyway. Nonetheless, the county was shaken with fear.
One rumor was that she had become possessed by the city man, who was regarded by many as some kind of demon. Others came forward and said they had observed strange behavior from Lady Silverheels in the days preceding her disappearance.
One man made the awe-inspiring connection that he had never once seen the lady in the same room as the sinister city man. And another said he stumbled upon the lady after leaving the distillery too early in the morning for any decent woman to be out and about. What's even more odd, she was rumored to be wearing the same dark grey overcoat as the man and when she turned to look, her face was ornamented with freakish wisps of hair, belonging to, logically, the miners who met death before a smallpox cure.
Recommended Stories For You
Was the lady a victim to the delirium of the virus or was she one in the same as the strange city man? We may never know.
Happy Halloween. We out.


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Consumer spending comprises the bulk of economic activity this week, so we get important business out of the way early with the retail sales report from the Commerce Department Monday at 8:30.
Handicapped by Washington
The consumer has been restrained to a degree by Washington. The payroll tax cut expired at the beginning of the year, and $85 billion in mandatory federal budget cuts, or the so-called sequester, began to take effect in early March.
Although it hasn't grabbed headlines lately, global growth continues to be a concern for the United States as well.
Retail 'sails' or hits the rocks?
The government reported a 0.4 percent drop in March retail sales. Jeffrey Rosen, chief economist with Briefing.com, says the next report won't be any better.
"The underlying trends point toward another month of declining sales. We already saw from the motor vehicle manufacturers that vehicles sales slipped by 2.6 percent in April," he says.
Rosen reminds that the jobs report released earlier this month showed a decline in wages, hurting consumers' ability to spend. He's looking for a decline of 0.5 percent or more in retail sales, close to what others are expecting.
Economic releases
- April retail sales: Monday 8:30 a.m. Eastern
- Housing starts: Thursday 8:30 a.m. Eastern
One wild card involves the recent drop in gasoline prices, something most of us have welcomed. While consumers get a break from falling gas prices, they show up as weaker sales in the dollar-denominated report. On the positive side, IHS Global Insight says if you factor out autos and gas, retail sales were probably up 0.4 percent in April.
Getting the statistics right also involves the impact of Easter sales, the timing of which vary from year to year.
"An earlier-than-usual Easter this year may have caused further havoc in the seasonal adjustment process," says economist Lynn Reaser with California's Point Loma Nazarene University.
"Higher employment, climbing home prices, and rising stock prices are all now supporting retail sales -- although the performance is likely to be uneven," she adds.
Chain store sales weren't too bad
One narrow preview of the government report is monthly chain store sales, out last week. The International Council of Shopping Centers reported a rise of 2.7 percent, compared to a year earlier.
The trade group's chief economist, Mike Niemira says, "Definitely the consumer is hanging in better than expected." Niemira also says the surging stock market, the improving housing market and rising home prices are helping.
Housing no longer a drag
The housing market is now adding to U.S. growth, in contrast to the dramatically negative influence linked to the Great Recession. The difference should be underscored with the release of April housing starts data later in the week.
John Canally, chief economist with Boston-based LPL Financial, notes "we're right in the heart of the spring selling season, and home prices are accelerating again." He says "housing is making a contribution to gross domestic product (growth), which it hasn't done since 2005 and 2006."
So where are we?
Canally says it will be hard to maintain the 2.5 percent growth rate reported in the United States for the first quarter of the year, in part because of the eventual negative impact of the sequester.
He says, "2 percent growth for the year still looks like the best bet."
That is not enough to substantially drive down the unemployment rate, despite better-than-expected hiring numbers and declining new claims for unemployment benefits. The subpar recovery story drags on, it appears.
This week in business history: Oscars anniversary
On May 16, 1929, the first Academy Awards ceremony was held at the Hollywood Roosevelt Hotel. Just 270 people attended and tickets were $5. Unlike the modern-day drama involving surprising nominees as well as the audience, the winners had been notified three months in advance. The policy was changed the following year, adding the element of surprise to the ceremony script.
How far has the industry come since then?
Just counting box office results alone, the Motion Picture Association of America says the total "for all films released in each country around the world reached $34.7 billion in 2012." Next year's ceremony will be the 86th for the Academy Awards.
Follow me on Twitter @hamrickisms.


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"We've got to be very clear about this. We don't want our players hanging around with murderers," said Larry Bird, Pacers president.
I had something going on tonight and couldn't watch this game. I'm glad to hear Lance is OK. This game looks like a typical win for a great team against an inferior opponent. We allowed them to hang around in the first half before putting a chokehold on them in the third quarter.
I can't wait to watch tomorrow night. If we go into Brooklyn and pull a win off, then the national media will really be buzzing.
Nuntius was right for a while. I was wrong for a while. But ultimately I was right and Frank Vogel has been let go.
"A player who makes a team great is more valuable than a great player. Losing yourself in the group, for the good of the group, thats teamwork."
-John Wooden
Others have already said it. We basically played bad yet won fairly decisively. Impressive. We just have so many talented players now that when you combine it with our amazing defense, we are just scary good right now.
I didn't get to see much of the game, mostly just the second quarter, but it pleased me to see Orlando be the spark off the bench that set the come back in motion.
Also, it was nice to have George Hill remind me tonight why he's the starting PG; he was great.
Wow...there is a low turnout for this Post game thread....everyone must still be in Downtown Indy...at Scotty's Brewhouse having a beer....or passed out at Scotty's Brewhouse while having TOO MANY beers in celebration of the 6-0 start.
Ash from Army of Darkness: Good...Bad...I'm the guy with the gun.
On Scola, courtesy of count55:
In 43 4th quarter minutes, Louis Scola has scored 30 points on 16 of 22 shooting and the Pacers are plus 34— Tim Donahue (@TimDonahue8p9s) November 9, 2013
(could have gotten Scola's first name right, though )
I feel bad for DJ Augustine. And probably all of the Toronto players if that's how their coach treats the ends of somewhat close games.
didn't they have an equally baffling ending In the game against Charlotte
I hate correcting Count, but.........16-22 is still 16 made shots, since the cheapest one is 2 pts, the 30 points can't be that right (providing of course he did not include ft's in there)
So Long And Thanks For All The Fish.
If you've done 6 impossible things today?
Then why not have Breakfast at Milliways!
I know there's no way to make it happen and we've already got the position filled, but man I'd love Amir Johnson as our backup 4. I love that dude.
We are much younger than the spurs, I think rest isn't too much an issue when your stars are 23 years old man. And we keep playing like this they will be sitting out the last few games anyway
yeah, having a 3 game lead in the Central a week and a half into the year is pretty cool
On a back to back against the Bulls, we played very well in the 4th quarter. I would say we have the advantage at least on that note against an older Brooklyn team. They did rest some of their starters, but against this Pacer team it may not matter. The one advantage Brooklyn has over Toronto is Lopez and the fact their old dogs are not going to try to go through Hibbert as much as shoot from the perimeter. I think it will be tough to beat them.
Lance is finally home. Whether he becomes our starting PG or he's 6th man, he's getting big minutes and he's here to stay. #llortontnia
He is also shooting 66.7% in Catch and Shoot situations. He is attempting 3.6 Catch and Shoot FGA per Game and making 2.4 of them. That should make Lance and PG very happy.
Speaking of Lance, he has already scored 42 points in Catch and Shoot situations. The only players that have scored more points in those situations so far are Klay Thompson and Kyle Korver. JJ Redick has 42 points as well but Lance beats him a lot in Catch and Shoot eFG% (Lance is at 77.8% while Redick is at 58.3%)
Tonight, all flags must burn, in place of steeples.
Autonomy must return into the hands of the people.
Refs HATE Ian
Maybe my definition is different from the tracking stats definition, but I'll have to watch Scola and Lance more specifically in those situations.
Sent from my TouchPad using Tapatalk 4
A bird in the hand is worth two in the bush.
Or throw in a first-round pick and flip it for a max-level point guard...
A two-page post-game thread? For shame, Pacers Digest. I know college basketball season just started, but show some respect. Get your priorities in order!
The nets are going to feel like they hit a brick wall tomorrow. I love it.
and has it been 3 weeks yet? What's our most recent granger report. Granger Watson scola Ian is better than some teams starting 4 and we have them as backups
Tonight, all flags must burn, in place of steeples.
Autonomy must return into the hands of the people.
I thought the B&G, especially Paul, looked like a 5-0 team playing a bad team in the first quarter. We can beat these guys by just showing up and playing. Good for Toronto and Rudy Gay for taking advantage of that lack of focus.
But it looked like the Pacers got their act together and settled themselves down. A nice example of just how well the Heat were playing last season. Nice professional effort.
Interesting bit of officiating last night. I've see guys miss calls before and be out of position before, but this was the first time I've seen a guy just not paying attention to the game. David Guthrie had one short stretch where he just stop watching the game. When guys went down he just kinda shook his head and said that had to be a foul and called it. Not a clue what actually happened. It was strange. Normally NBA officials are pretty focused.


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Michigan State coach Mark Dantonio announced the hiring of Jim Bollman on Monday as well as some other moves within his coaching staff.
Bollman, who coached the offensive line and running game at Boston College last season before being hired to coach the offensive line at Purdue last month, will be the co-offensive coordinator and coach tight ends at Michigan State.
Bollman was the offensive coordinator/offensive line coach at Ohio State from 2001-11.
"This is the fourth time in my career that I've had an opportunity to work with Jim Bollman, so there's definitely a comfort level there," Dantonio said in a statement. "He has a tremendous amount of football knowledge, especially on the offensive side of the ball. In addition to serving as co-offensive coordinator, Jim will coach the tight ends, and he spent three years coaching that position in the NFL. He also has long-standing recruiting ties in Ohio. We're excited about having Jim and his family back in the MSU community."
Bollman will share offensive coordinator duties with Dave Warner, who previously coached quarterbacks. He will now coach running backs, along with his coordinator duties.
Also, defensive coordinator Pat Narduzzi added assistant head coach to his title.
Brad Salem, who coached Michigan State running backs the past three seasons, will coach quarterbacks.
Dantonio said he's eager to get spring practice started with the changes made on the offensive side of the coaching staff.
"We might simplify some things, yet become more diversified as an offense," Dantonio said. "Throughout the spring, things will be added and subtracted from the offense. Changes aren't being made for the sake of change; changes are being made with a purpose. With that mindset, we can create different opportunities for our playmakers."


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Dan Weinfurter and J.P. Donlon
1 POSTS 0 COMMENTSDan Weinfurter is CEO of GrowthPlay. J.P. Donlon is Editor in Chief at Chief Executive magazine.
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Josh Thompson's Got A New Look
Josh Thompson has a new look!
He showed it off last night on Twitter while at the Grand Ole Opry. He says he agreed to let People Country cut off his ponytail in celebration of his upcoming album 'Turn It Up' which will be out April 1.
And yes, that is Trace Adkins next to him. Last night was his first appearance on stage since the death of his father and a stay in rehab.
Said hey to @TraceAdkins tonight at the @Opry! pic.twitter.com/DBZkh0JJlN
— Josh Thompson (@TheJoshThompson) March 12, 2014
Source: Taste Of Country


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Officials in Washington state are warning consumers to stop drinking raw milk from a local dairy after tests found E. coli in one of the dairy's raw dairy products.
According to the Washington State Department of Agriculture, raw Jersey whole milk, raw Jersey skim milk and raw Jersey cream from Dungeness Valley Creamery in Sequim, Wash., may be contaminated with E. coli.
Officials warn that E. coli can produce a toxin called Shiga, which can lead to severe illness. The infection can also cause hemolytic uremic syndrome, which can be especially dangerous for people with compromised immune systems.
Dungeness Valley Creamery issued a statement in response to the confirmed contamination.
They wrote: "On Friday February 22nd we were informed there was a "Cannot Rule Out" (CRO) result on this product for a Shiga toxin-producing E. coli (not 0157H7). We took immediate action and within the same day contacted nearly all retailers and consumers letting them know to discontinue use of this product until further notice and in either outcome, they would receive a full refund. More importantly, there have been no reported illnesses at this time."
The dairy is working with officials to find the source of the contamination and have placed safety, consumer health and transparency as top priorities. Read their full statement here.


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Share-croppers have one or two room shacks
Two small African American children sit on the porch of a share-cropper's shack in Mississippi County, Arkansas.
8.3 x 10.2 cm
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Oscar Parties Best Dressed | Fashion 2013 (Video)
Oscar Party Fashion! Jennifer Lawrence and Nina Dobrev Celebrate in Style
Stars shined at all the glamorous Oscars fetes last night, and we've rounded up our favorite party looks right here. Jennifer Lawrence dazzled in Calvin Klein, Amy Adams went metallic in Oscar de la Renta, and Ginnfer Goodwin gave us a futuristic feel in Monique Lhuillier. Allison McNamara and Matthew Rodrigues are breaking it down in today's Oscar party recap! On Allison McNamara: Prabal Gurung dress from Rent the Runway.


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Nursha Project Guest Curates Late Night with Mason Rhynes Productions in DC
December 31, 2010 by Nursha
Filed under Community Events & News, Uncategorized
Comments Off on Nursha Project Guest Curates Late Night with Mason Rhynes Productions in DC
Join Nursha Project in celebrating Late Night with Mason Rhynes Productions. If you missed the December 2010 installment of the performance series, click here for details.
The April 30th edition of Late Night with Mason Rhynes is one you will not want to miss! Nursha Project is proud to co-curate this production!
April 30th, 2011 at 10pm
Late Night at Joe's Movement Emporium
3309 Bunker Hill Road
Mt. Rainier, Maryland
Featuring A.O. Movement Collective, Wendell Cooper, and other special guests!
Co-presented with Joe's Movement Emporium
Tickets: $20 General Admission; $15 Student Tickets with ID
Must be 18 to attend
Featured Artists
A.O. Movement Collective will be performing their piece, "Wet."
Choreographed by Sarah A.O. Rosner + dancers
Performed by Tara Aisha Willis
Music by The Idiot
Additional choreographic research by Kirstan Clifford
This excerpt is one section of our larger work in process, barrish, or: i promise i'll only look at the sky (goddamn black fucking hole). La Mama Experimental Theater will present the (pre)premiere of the work at La Mama Moves! this May 27/28 in NYC. The entire work is transmutable – able to be put together in any configuration for any space – and available for curation by anyone interested. Find out how you can participate at www.theAOMC.org/menu
Founded in 2006, the A.O. Movement Collective is a home for hard falls and heavy slow dances: a community of dancers, thinkers, and makers who live by their art. The AOMC encompasses my choreographic work; when joined with blog Urgent Artist and freelancing collective A.O. PRO(+ductions), it is the movement third of a platform representative of a new model for dancemaking.
Choreographically, the AOMC pioneers pomo-humanism via a rigorous love affair with the aesthetics of mess. At the same time, we are developing a discourse of anti-ephemeralism that surrounds our dancemaking. We believe that by actively questioning the underlying assumptions of our field (be they artistic or economic) we become radical agents of progress, evolving the form and creating a more sustainable future.
Performer Bios:
TARA AISHA WILLIS (dancer) dances, makes dance, and writes things from her overly cozy apartment
in Brooklyn. She graduated Summa Cum Laude from Barnard College in 2009 with a B.A. in Dance and English, where she performed the work of Sean Curran, David Parker, Ivy Baldwin, Yanira Castro, Stephen Petronio, Gerald Casel, Nora Chipaumire, and Susan Rethorst. She received the Dance Theater Workshop Van Lier Fellowship just after college, and has shown work at DNA's Works-In-Progress and Green Space's Fertile Ground Series. Tara's newest works will be presented this spring as an Alumni Guest Artist at The Latin School of Chicago, at the new REHEARSAL workshop series, and in the RoofTop Dance Series. Aside from The A.O. Movement Collective, Tara has most recently danced with Sydnie L. Mosley Dances, Anna Brown Massey and Edisa Weeks. She is completing her Pilates Teacher Certification at The Kane School, and teaches at the Pilates Garage in Park Slope. She supports her artistry as a freelance writer for A.O. Pro(+ductions), House Manager at Dance Theater Workshop, and hostess at Joe's Pub. www.bodypoem.blogspot.com
The IDIOT (composer) is the performing Alias of THEODOR WILSON, a performing artist living in Brooklyn, NY. He calls his style of music "ElectroDrama," because it combines trashy electronic riffs with melodramatic narratives, and because his live shows incorporate theatrical devices. Related genres include post-punk cabaret, new romantic, and industrial pop. Wilson is a trained pianist and occasionally performs acoustic versions of his electronic numbers.
The Idiot has referred to his persona as a "grotesque bitch," and a "harlequin." In concert, as well as in promotional appearances, he often wears articles of women's clothing, notably high-heeled shoes, but insists he is not a drag queen, and that drag is "its own medium, with its set of own rules." However, The Idiot does perform under the rap alias, "HamSamwich," a self-described drag queen to end all drag queens, whose numbers often appear in the Idiot's live act. The Idiot released his first official album, called "JUVENAL!A," in 2010.
Wilson has collaborated with Rosner and the AOMC since 2007, and has scored both her performance works (Haunt, The What's Left Over After) and short films (Flour, Eggshells, Study #4). He has also appeared in her performance works (in Love and Defense of the Ones I Destroy, barrish) and is a performative force to be reckoned with. The composition he created for The What's Left Over After appears on his 2010 album JUVENAL!A.
SARAH A.O. ROSNER is the founder of A.O.3 (the A.O. Entity), a three-part platform uniting the A.O. Movement Collective, freelancing collective A.O. PRO(+ductions), and the Urgent Artist blog. A.O.3 represents a new model for downtown dancemaking by holistically supporting all involved – artists, audience, funders, and critics. When not working on her own ventures, she is the Manager of Engagement at New York Live Arts in NYC.
Born and raised outside of Washington, DC, Rosner attended Sarah Lawrence College in New York where she studied dance and film with teachers including Emily Devine, Sara Rudner, Keith Sabado, Tony Schultz, and Kathy Westwater. Rosner founded the A.O. Movement Collective in 2006, and has been at their helm creating Anti-Ephemeral PoMo Humanist discourse and works ever since, presenting work at the RAW festival, THROW, Open Perform, WAXworks, Green Space, AUNTS, Dance Place (DC), the LaGuardia Performing Arts Center and most recently, Joyce SoHo.
WENDELL COOPER is is modern shaman and creative artist based in Brooklyn, NY. A graduate of the
George Washington University (Dance/Religion), he is also a certified practitioner of energy bodywork and Thai Yoga Massage. He has taught, performed, and choreographed in China, Kenya, Russia, and the Netherlands. Cooper creates all of the elements of his interdisciplinary multimedia works that include both choreographed and improvised dance, original music, and video installation. He has worked with Nicholas Leichter Dance, the Maida Withers Dance Construction Company, Grisha Coleman, and the Magpie Music Dance Company. Wendell also self- produces as well as collaborates on projects with Mathew Heggem (as Kinaeathesia), Monstah Black, and Yozmit. SEA GLASS is his latest collaborative project. [www.complexstability.com]


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Curried Lentil Soup with Cilantro
(Makes about 4 servings, recipe adapted slightly from Fine Cooking Annual Volume 3. This recipe would be perfect to make a double batch and put some in the freezer.)
1 T minced garlic (I used minced garlic from a jar)
fresh ginger root, big enough piece to make 1 T minced ginger
1/2 cup chopped celery (or fennel)
1 cup chopped carrot
1/2 onion chopped
2 T olive oil (use more or less, depending on your pan)
1 T curry powder (I used Penzeys Sweet Curry Powder)
1 cup brown lentils
1 quart chicken stock
salt and fresh ground black pepper to taste
chopped cilantro or parsley to garnish the soup
Add lentils and chicken stock, bring soup to a boil, then reduce heat until soup is gently simmering. Cover pan and cook until lentils are soft, about 45 minutes.
When lentils are soft, puree half of soup mixture. (I used my immersion blender but if you don't have an immersion blender, remove half of soup to a blender or food processor and puree, then add back into the soup. Be very careful when blending or processing hot liquid.) Taste soup and season as desired with salt and fresh ground black pepper. Garnish with chopped cilantro (or parsley if you're not a cilantro fan.)
South Beach Suggestions:
So Many Delicious Versions of Lentil Soup:
(Recipes from other blogs may not always be South Beach Diet friendly; check ingredients.)
Vegetarian Lentil Soup with Spinach, Tomatoes, and Cumin from Kalyn's Kitchen
Lentil Soup with Ground Beef and Brown Rice from Kalyn's Kitchen
Lentil and Sausage Soup with Sweet Potatoes and Herbs from Kalyn's Kitchen
Lentil Soup with Italian Sausage and Roasted Red Peppers from Kalyn's Kitchen
Lentil and Sausage Soup with Cabbage from Kalyn's Kitchen
Pomegranate Lentil Soup from The Kitchn
Hearty Lentil Soup with Carrots, Tomatoes, and Smoked Sausage from Farmgirl Fare
Red Lentil Soup with Garam Masala from Je Mange la Ville
Spicy Red Lentil and Tomato Soup from Andrea's Recipes
Spicy Lentil Soup with Lime from Nami Nami
(Want even more lentil soup recipes? I find these recipes from other blogs using Food Blog Search.)


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A Monterey man was sentenced to 16 years to life in prison Tuesday for the second-degree murder of the man he believed was his romantic rival.
Brandon Henley, 20, was in the midst of his trial in August when he pleaded guilty to fatally stabbing Daniel Ryan Youngblood, 23, the son of retired Marina police officer Walter Youngblood.
According to testimony, Henley attacked Daniel Youngblood on Sept. 4, 2011, after he and his ex-girlfriend argued over texts she was exchanging with Youngblood.
Before the attack, the woman had ordered Henley out of her apartment. Thirty minutes later he returned with a knife, watched the victim drive into the apartment complex, punctured his tire, then turned on him.
Forensic pathologist John Hain testified Youngblood was stabbed more than 15 times and that his fatal injuries were consistent with defensive wounds.
Henley, who had punctured the victim's tires a month before the killing, was quickly identified as the key suspect. He later told police Youngblood punched him in the face and pushed him against the car, where he struck his head.
In testimony in a preliminary hearing, Henley claimed he struggled with Youngblood, believing he had a gun. He said he had no memory after slashing Youngblood's arm.
Henley went to trial facing a first-degree murder charge. Prosecutor Jeannine Pacioni was preparing to wrap up her case and hand the trial to defense attorney Frank Dice in August when Henley abruptly accepted a previously offered plea deal.
Judge Pamela Butler sentenced him to 15 years to life in prison with an additional year for use of a knife.


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Vorinostat in Treating Women With Ductal Carcinoma in Situ of the Breast
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RATIONALE: Vorinostat may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
PURPOSE: This clinical trial is studying how well vorinostat works in treating women with ductal carcinoma in situ of the breast.
|Breast Cancer
|Drug: vorinostat Genetic: protein expression analysis Other: immunohistochemistry staining method Other: laboratory biomarker analysis Procedure: neoadjuvant therapy Procedure: therapeutic conventional surgery
|Phase 1
|Study Type:
|Study Design:
|Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Other
|Official Title:
|A Window Trial of Vorinostat in Patients With Ductal Carcinoma in Situ (DCIS) of the Breast
- Reduction in Ki-67 compared to baseline Ki-67 [ Time Frame: 3 days prior to surgery ]
- Changes in HDAC1 and HDAC6 expression and histone H4 and α-tubulin acetylation in breast tissue and serum samples [ Time Frame: 3 days prior to surgery ]
|Study Start Date:
|July 2009
|Study Completion Date:
|August 11, 2015
|Primary Completion Date:
|November 3, 2011 (Final data collection date for primary outcome measure)
|Assigned Interventions
|Experimental: Vorinostat
|Drug: vorinostat Genetic: protein expression analysis Other: immunohistochemistry staining method Other: laboratory biomarker analysis Procedure: neoadjuvant therapy Procedure: therapeutic conventional surgery
Detailed Description:
- To evaluate the in vivo molecular and biological effects of vorinostat by analyzing changes in proliferation and apoptosis, histone acetylation, and HDAC protein expression in women with ductal carcinoma in situ of the breast.
OUTLINE: Patients receive oral vorinostat twice a day for 3 days in the absence of unacceptable toxicity. Patients then undergo lumpectomy or mastectomy 2 hours after the last dose of vorinostat.
Blood and tissue samples are collected at baseline and during surgery for biomarker laboratory studies. Samples are analyzed by immunohistochemistry for Ki-67, HDAC1 and HDAC6 protein expression, and histone H4 and α-tubulin acetylation.
After completion of study therapy, patients are followed for 1 month and then every 6 months for 5 years.
|Ages Eligible for Study:
|18 Years to 120 Years (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Histologically confirmed (by core biopsy) ductal carcinoma in situ
- Stage 0 disease
- Hormone receptor status not specified
- Menopausal status not specified
- ECOG performance status 0-2
- ANC ≥ 1,500/mm^3
- Platelet count ≥ 100,000/mm^3
- Hemoglobin ≥ 9 g/dL
- Potassium and magnesium levels normal
- Prothrombin time or INR ≤ 1.5 times upper limit of normal (ULN) (unless the patient is receiving therapeutic anticoagulation)
- Partial thromboplastin time ≤ 1.2 times ULN (unless the patient is receiving therapeutic anticoagulation)
- Serum creatinine ≤ 1.5 times ULN OR creatinine clearance ≥ 60 mL/min
- Not pregnant or nursing
- Negative pregnancy test
- Fertile patients must use 2 effective barrier methods of contraception
- No known psychiatric or substance abuse disorder that would preclude cooperation with the study requirements
- No active hepatitis A, B, or C infection
- No active HIV infection
- No other active infection
- No other malignancy within the past 5 years
- No condition that would interfere with the absorption or intake of vorinostat
- No history or current evidence of any condition or laboratory abnormality that would confound study results, interfere with the patient's participation in the full duration of the study, or that would not be in the best interest of the patient to participate
- More than 2 weeks since prior IV antibiotics, antivirals, or antifungals
- No prior gastrointestinal surgery or other procedure that would interfere with the absorption or intake of vorinostat
- No prior or concurrent therapy with any other HDAC inhibitor, including valproic acid
- No prior treatment with any other investigational agent
- No concurrent systemic steroids
- No concurrent anticancer chemotherapy, radiotherapy, biological therapy, or other investigational therapy
Please refer to this study by its ClinicalTrials.gov identifier: NCT00788112
|United States, California
|UCSF Helen Diller Family Comprehensive Cancer Center
|San Francisco, California, United States, 94115
|Principal Investigator:
|Laura Esserman, MD, MBA
|University of California, San Francisco
|Responsible Party:
|University of California, San Francisco
|ClinicalTrials.gov Identifier:
|NCT00788112 History of Changes
|Other Study ID Numbers:
|Study First Received:
|November 7, 2008
|Last Updated:
|August 4, 2017
Keywords provided by University of California, San Francisco:
ductal breast carcinoma in situ
Additional relevant MeSH terms:
Carcinoma in Situ
Carcinoma, Ductal
Carcinoma, Intraductal, Noninfiltrating
Neoplasms, Glandular and Epithelial
Neoplasms by Histologic Type
Neoplasms, Ductal, Lobular, and Medullary
Antineoplastic Agents
Histone Deacetylase Inhibitors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
ClinicalTrials.gov processed this record on September 21, 2017