text:
Laparoscopic Gastric Bypass for Type 2 Diabetes Mellitus With Body Mass Index (BMI) < 35
Recruitment status was: Recruiting
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- No Study Results Posted
- Disclaimer
- How to Read a Study Record
|Diabetes Mellitus, Type 2
|Procedure: Gastric bypass for diabetic patients <35 BMI
|Study Type:
|Study Design:
|Allocation: Non-Randomized
Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
|Official Title:
|Laparoscopic Gastric Bypass for Type 2 Diabetes Mellitus: a Pilot Prospective Study in Overweight and Mildly Obese Subjects
- Hemoglobin A1C changes [ Time Frame: Post gastric bypass operation ]
- improvement in glycemic control [ Time Frame: 1 to two years ]
|Estimated Enrollment:
|Study Start Date:
|October 2009
|Estimated Study Completion Date:
|November 2013
|Estimated Primary Completion Date:
|October 2011 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: diabetic pts <35BMI
All patients will be in a single arm receiving bypass surgery to assist with diabetes management
Procedure: Gastric bypass for diabetic patients <35 BMI
The operation is performed under general anesthesia. It is done laparoscopically, meaning that several small openings are made in the abdomen for insertion of long, thin surgical instruments, one with an attached camera. The operation is video monitored. The top of the stomach is divided across, leaving a small pouch for food. The rest of the stomach remains but can receive no food. The gut is divided just past the stomach, and it is attached to the small stomach pouch so that food can get back into the bowel. A second connection is made so that the bile and digestive juices pass into the bowel with the food.
Other Name: gastric bypass surgery
Detailed Description:
The primary endpoint will be the reduction of HbA1c and secondary endpoints will be multiple associated parameters as listed below. A group of 50 subjects with medically documented T2DM and BMI of 26-35 will undergo standard laparoscopic RYGB. Prior to surgery, the subjects will undergo the standard pre-operative work up required for conventional bariatric surgery. This includes full history and physical exam, medical/cardiac clearances as needed, nutrition consultation and a gastrointestinal consultation for upper endoscopy. After thorough explanation an approved informed consent will be signed. Baseline parameters, as listed below, will be measured for each subject to identify possible complications of diabetes prior to the surgical intervention..
After surgery perioperative complications will be monitored and required modifications of diabetes management advised. Followed up measurements at 1, 3, 6, 12, and 24 months is consistent with standard clinical practice guidelines. Data analysis will be ongoing to observe the effects of the surgical intervention on glucose homeostasis.
- Baseline parameters
- History and Physical Exam
- Weight/BMI/ body composition with the Tanita 310.
- Waist Circumference
- Blood Pressure
- HbA1c
- Fasting glucose
- Vitamin B6, B12, Folate,and Iron status
- Lipid Profile -total cholesterol, HDL, LDL, triglyceride
- Fasting Insulin and C-peptide
- Stimulated C-peptide
- Retinal exam
- Urinalysis (assess for proteinuria and microalbuminuria)
- Comprehensive foot exam
- Medications and dosage
- Quality of Life Score (SF-36)
- Carotid ultrasound (intima-media thickness)
4 Weeks:
- Physical Examination, wound check, Body weight, BMI,
- Glucose Diary (pre and postprandial glucose levels as required)
- Insulin and C-peptide
- Lipid profile
Medication use
3 Months, 6 months,
Same as above plus:
- HbA1c
- Vitamin levels and iron status
- Retinal exam
- Annually the baseline measurements will be repeated
|Ages Eligible for Study:
|18 Years to 65 Years (Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
Adult males and females who meet the following inclusion criteria will be offered the opportunity to participate in the study:
Diagnosis of type 2 Diabetes Mellitus (T2DM) confirmed by the following criteria:
- normal or high C-peptide level (> 0.9 ng/ml) to exclude type 1 Diabetes Mellitus
- positive glucagon test to confirm T2DM
- fasting plasma glucose of 126 mg/dl or more on at least two occasions
- Body mass index (BMI) 26 kg/m2 or greater, and less than 35 kg/m2
- History of T2DM for not longer than 8 years, as long-standing disease beyond 8 years correlates with failure to achieve diabetes resolution after gastric bypass
- No contraindication for surgery or general anesthesia as determined by a multidisciplinary bariatric surgery team (surgeon, anesthesiologist, internist, dietitian, psychologist)
- Between 18 and 65 year of age
- Able to provide informed consent
- If a female with reproductive potential, she has to agree to use a reliable method of birth control for at least one year from the date of surgery
Exclusion Criteria
Subjects who meet any of the following exclusion criteria will not be eligible to participate in the study:
- Enrollment in another clinical study, which involves an investigational drug
- Diagnosis of type 1 Diabetes Mellitus or other genetic forms of Diabetes Mellitus
- Significant renal failure of chronic liver disease (except NAFLD)
- Major psychological disorders
- Pregnancy - all female subjects will have serum beta-hCG prior to operation, and must use birth control of their choice to avoid pregnancy during the first year after surgery
- Previous gastric or esophageal surgery
- Immunosuppressive drugs including corticosteroids
- Coagulopathy defined as an INR > 1.5 or platelet count < 50,000/µl
- Anemia defined as a Hb <10.0 g/dl
- Inflammatory bowel diseases or other medical condition that would serve as a contraindication to gastric bypass (eg. celiac sprue, pancreatic insufficiency)
- A severe concurrent illness that is likely to limit life or require extensive systemic treatment (e.g. cancer)
A pre-existing major complication of diabetes:
- unstable, proliferative retinopathy
- severe autonomic cardiac neuropathy or intestinal neuropathy
- Myocardial infarction within the previous year, current unstable angina, or poorly-controlled congestive heart failure (Stage III)
Please refer to this study by its ClinicalTrials.gov identifier: NCT00999050
|Contact: Maureen Morrison, MSN-ACNP, DNPc
|Contact: Tina Chuck, MPH
|United States, New York
|Weill Cornell Medical College New York Prysbyterian Hosptial
|New York, New York, United States, 10065
|Contact: Francisco Rubino, MD 212-746-5925 email@example.com
|Contact: Gladys W Strain, PhD 212-746-5661 firstname.lastname@example.com
|Responsible Party:
|Francesco Rubino, MD, Assistant Professor, Weill Medical College
|ClinicalTrials.gov Identifier:
|NCT00999050 History of Changes
|Other Study ID Numbers:
|Study First Received:
|October 14, 2009
|Last Updated:
|January 3, 2011
Keywords provided by Weill Medical College of Cornell University:
type two diabetes
gastric bypass surgery
overweight or moderately obese
Additional relevant MeSH terms:
Diabetes Mellitus
Diabetes Mellitus, Type 2
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases
ClinicalTrials.gov processed this record on September 21, 2017


text:
Over the past several decades being a CoverGirl has become an iconic and coveted title (think America's Next Top Model's $100,000 contract prize!), featuring faces that include everyone from girl-next-door, Christie Brinkley to sassy Rihanna. The latest addition to the CoverGirl lineup? Sofia Vergara! The Emmy nominated actress and star of Modern Family is shooting her very first ad campaign that will launch in January 2010. We're so excited, we thought we'd take a look back at some of our other favorite CoverGirls too!
Cybill Shepard plays up her signature crystal clear eyes with blue shadow in this 1971 CoverGirl New CoverGirl Eyes commercial.
Try: Update this look by playing with navy eyeliner on your bottom lid. Use natural blush and a neutral-toned lipgloss, so your eyes really pop.
Christie Brinkley flaunts a flirty pout in this 80s CoverGirl Lip Advance commercial (she's been a CoverGirl since 1976 and reprised her role in 2005 after a decade away!)
Try: Play up pretty lips with fun lashes. Choose a mascara that lengthens and curls and apply two coats for peepers that flirt along with your lips.
Queen Latifah brings bright eyes up to date in this commercial for CoverGirl Exact Eyelights Collection.
Try: Smokey eyes with purple! Sweep your shade over your top lids and smudge it a bit on your bottom lids for a flirty look that's not overdone.
Ellen DeGeneres' CoverGirl Simply Ageless commercials, she celebrates aging gracefully with her famously awkward humor.
Ellen DeGeneres' CoverGirl Simply Ageless commercials, she celebrates aging gracefully with her famously awkward humor.
Try: For truly flawless application, remember to prep your skin for makeup with a primer. It'll help it go on more smoothly so it won't highlight fine lines and wrinkles.
Rihanna's music video style commercial for CoverGirl Wet Slicks Fruit Spritzers makes us want to dance!
Try: New bold lips for spring. Don't forget to line your lips with a waxy lip pencil that's close to the shade of your lip color. Then fill in with a lip brush, being careful to stay within your lip line.
What do you think Sofia will bring to her newest role as a CoverGirl?
Check out these fun extras:
Posted by Pia Bhattacharya

subset: commoncrawl


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Corinth youngster makes move to stock cars
Cole Glasson's life has taken a left turn — one the racer from Corinth hopes to steer right into NASCAR's winner's circle.
Never mind that he's 12 years old and weighs only 75 pounds.
The Crownover Middle School seventh-grader is one of racing's up-and-comers. He has a two-year contract to drive on the JEGS/Champion Racing Association All-Stars Tour to prove it.
"Cole is exactly the type of young, talented driver we like to provide opportunities to in our driver development program," former NASCAR driver Andy Ponstein said when announcing the signing of Glasson to Andy Ponstein Racing. "He did an outstanding job with the test in December at Anderson Speedway, and the entire crew was impressed with what they saw."
In two years, Glasson has gone from professional go-karting to dirt track midgets to full-size late-model stock cars on asphalt ovals.
"I used to dread racing on ovals," Glasson said. "I thought it'd be boring, but when I did it [racing midget cars], it wasn't. I used to think my profession was going to be Formula One, like the IndyCar Series, but now I'm thinking NASCAR."
After winning 23 percent of the go-kart races he entered since he began racing as a 5-year-old, Glasson raced eight times against adults in last summer's USAC Ford Focus Midget Series, finishing third his last time out and sixth for the season among rookies.
In December, Glasson went with his father, Tim Glasson, and agent, Tonya McCallister, to Anderson Motor Speedway in Williamston, S.C., to test-drive for Ponstein's team. The contract he received was his seal of approval from Ponstein, who started 26 Nationwide Series races between 2004 and 2011.
"Cole has significant experience and accomplishments for such a young age and is a pleasure to work with," said McCallister, president of MPM Marketing. "He is going to be a positive representative for companies on and off the track, and we are looking forward to building some great partnerships."
Racing is in Cole's blood. His mother is Wendy Glasson, and her father, Robert Morris, raced sprint cars throughout northeast Texas. Two of Cole's uncles also raced.
"My dad took me to the Indianapolis 500 when I was 5, and I loved it," Cole said. "He asked me, do I want to race?, and the answer was a definite yes."
Cole's trophy wall at home includes a photo of him suited up for his first go-kart race. The kart isn't much bigger than a small push mower, but it's bigger than the driver.
The kid with a need for speed doesn't like sitting still. He was runner-up for a national championship at age 6 and collected the first of his three national go-kart titles by the time he was 8.
Karting required frequent travel to California for races — trips for the entire family, including 16-year-old sister Alexa. Competing in midgets required a waiver of the minimum age requirement of 12.
The Champion Racing Association requires drivers to obtain special certification if they're under 15. If Glasson gets it, he will be the youngest driver ever on that circuit.
"After completing the CRA driver approval process for drivers under the age of 15, Cole will begin testing immediately with the team to prepare for the season opener on April 7 at Illiana Motor Speedway," Ponstein said in a news release.
The CRA All-Stars Tour includes 13 races on 11 tracks in Michigan, Indiana and Ohio, with 24 to 28 cars in each field.
Cole knows he's in for several big changes. After driving a 900-pound, 185-horsepower open-wheel midget in 2012, the late-model he will drive for Ponstein can turn out 400 horsepower and weigh 2,800 pounds.
Race distances will increase from about 30 laps in midgets to 100 laps on the All-Stars Tour.
"I've never had a closed car before," Cole said. "Just the size of the car is a big adjustment. It probably weighs two to three times more than the ones I've been in. And since it's a lot bigger, I have to definitely keep my upper body strong.
"The races typically last an hour or so, and since it's not a road course, you're always turning left. That puts more pressure on your arm."
The young driver builds upper body strength in the weight room at school and in a small home gym. He builds endurance by running 30 to 40 miles per week with Lake Cities Cross Country.
"The most important thing is seat time," Cole said. "You just have to be in the car as much as you can. And you have to take advantage of practice to work with the tuners and make sure you get the car right.
"Then it's all on the driver to drive it to the capacity of the car."
Glasson's next goal is the NASCAR Camping World Truck Series. The age requirement there is 16.
In the meantime, he'll keep growing his brand and picking up new fans. There's no age limit for that.
"When I'd race in the midgets, we'd have autograph sessions. All these little kids would come up to me and want autographs," Glasson said. "I guess they look up to me because I'm a little kid taking on older drivers."
And how do the older drivers feel?
"Actually, racing against me makes them want to win more," he said. "They don't want a 12-year-old to beat them."


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Tillamook Air Museum's future is in... Madras?
TILLAMOOK, Ore. - One of Tillamook's most well-known attractions that draws in tens of thousands of visitors every year will be making a big move across the state.
We're talking about the Tillamook Air Museum - that huge WWII blimp hangar that houses a vintage aircraft collection owned by Erickson Group,. Ltd., along with U.S. Navy aircraft on loan to the Port of Tillamook Bay and a few donated planes.
Erickson, which leases the hangar that you can't miss when you're driving down Highway 101 in Tillamook, has decided to move their aircraft to Madras (a small town about 40 miles outside of Bend).
The company recently purchased an air-tanker operation at the Madras Municipal Airport and decided that Central Oregon's dry climate is a much better place to store the vintage aircraft they have had on display in Tillamook for years.
"I think moving the airplanes is a great thing because the climate over here (in Tillamook) is pretty harsh on the airplanes and the metals," Tillamook Air Museum's manager, Michael Oliver, said. "Over there in a drier climate you can preserve the airplanes a lot better."
Erickson is planning on building a new 65,000-square-foot hangar in Madras, in addition to the existing 22,000-square-foot hangar that's already there. That will give them more space for air tanker operations, but it will also give them plenty of room for a museum. Construction on the new hangar is scheduled to begin this summer.
So when can we expect the airplanes to leave the Tillamook Air Museum? There is no set date but Erickson's lease from the Port of Tillamook Bay does end in 2016.
Oliver said the Tillamook Air Museum gets around 65,000 to 70,000 visitors a year. That's certainly a lot of tourism going away and we asked him if he has gotten any feedback from the community. He said they did get quite a few comments on Facebook after they posted the press release with the announcement. Here are a few:A lot easier to go to Tillamook than Madras...going to miss that place. - Dave WileyNow I'll have a reason to visit Madras a couple of times per year. I hope there will be a big celebration and photo op day with all the aircraft on display at once before they are flown to Madras. - Kurt LivermoreIt's too bad. Those blimp hangers are such an important part of the history of Tillamook. My father helped build them. I really hope that the Port of Tillamook will some how protect it for the future. - Janie Bishop
That's very sad and upsetting. Not only for the people of Tillamook, but for those who came to see a piece of history in a magnificent building. Not to mention, I don't even know where Madras is. - Tammy Wilhite BielasWell that is a great big bummer for all of us coast people. I am sure the new facility will go way up in price.... any ideas what is going to happen to the hanger here in Tillamook? - Tom ThiesSo use the hanger for something else. It is already being used for certain storage. Many other uses could be put in place! - Ray Vern Steele
There are around 30 aircraft in the hangar at the Tillamook Air Museum and Oliver said only the ones owned by Erickson will be moving to Madras. The others will be left behind.
We contacted the Port of Tillamook Bay, which just found out about Erickson's plans a few weeks ago, for some insight into what might become of the air museum hangar. As you can imagine, this is all fairly new to them and not much has been decided at this point.Photo courtesy glenbledsoe on Flickr (Creative Commons).
"We will be working with the Erickson group on a transition, but we don't know what that will look like yet," Michele Bradley, general manager for the Port of Tillamook Bay, told us in an e-mail. "The Port of Tillamook Bay would be open to considering all options, which might include leasing it as a museum again."
"This is a great loss for Tillamook County," Bradley added. "It is a well-visited tourist stop."
As we mentioned, some of the airplanes at the museum are on loan to the Port of Tillamook Bay from the U.S. Navy and those will not be going to Madras. According to Bradley, they will either stay with the port or be returned to the U.S. Navy, a decision that will be determined at a later time.
Bradley told us that the Port of Tillamook Bay and legal counsel are reviewing Erickson's lease and plan to meet with the company to discuss how best to move forward.
In the meantime, things are already happening at the Madras Municipal Airport. Airport manager Rob Berg told us Erickson has been on site since November and he's hoping they'll be bringing their vintage aircraft there and opening the museum by 2014.
Berg said he sees this as a win-win for a number of reasons. Nearby Bend and the surrounding area already gets a lot of visitors and Berg said this will give folks one more attraction to see.
"It'll be not just for our town, but all of Central Oregon," he said.
Berg also believes it was a smart move on Erickson's part to move all of their operations to one place. And he said they could not have picked a better location for aircraft operations.
"Our weather over here is phenomenal compared to Tillamook," he said.
The airport in Madras is also the site of the second largest air show in the Northwest - The Airshow of the Cascades that's held every year in August - and Berg is excited that there will be another element to add to the event once the museum opens.
"It's kind of like a marriage made in heaven when you have an airshow and an air museum," he said.Photo courtesy of the Airshow of the Cascades on Flickr.


text:
Home I Reggae Lyrics I Videos I Dancehall Riddim I Dancheall Singles I Sound Effects I Whats New I Reggae Riddims
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Dancehall and Reggae 2012 Riddims - The year 2012 saw a number of chart-topping dancehall and reggae music's singles and riddims also known as juggling.
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Dancehall Queen Carlene joins Danielle D.I. on new Ishawna Diss Track - New York, NY, September 17, 2017 – The original Dancehall Queen Carlene has joined Rebel singay,
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There's something about you girl And I don't think it's just your smile I dunno how to say it now, I've been thinking for a while The best way to say it
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Chimney Waaahaa Dah dance yah get the people dem crazy now World a rock Dance globally You nuh see say energy a rock the world You nuh see say Kool Kid
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I had heard this song from a choreo video I seen on instagram and from the sound of it it seemed like it belonged in this genre, I tried searching everywhere
Jamaica Sunshine Tours is an authentic Jamaican Tour Company


text:
UPLAND – Registration is under way for the Challengers Bowling League that will run from March 16 to June 8 for special-needs children and adults 10 years and older.
The program holds bowling Saturdays at 10 a.m. in Upland for 12 weeks. The cost is $6 each week.
To register: Jack or Cora Peterson at 909-225-9076 or 909-987-7276.


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DUDLEY borough residents are being offered the chance to get fit at a Brierley Hill boot camp.
The Dell Stadium, Bryce Road, is offering the outdoor Sunday morning session for people aged 16 and over of all abilities.
Led by a fully qualified instructor, it runs from 9.30am to 10.30am and includes an intense and fun workout for the whole body.
Councillor Stuart Turner, Dudley cabinet member for health and wellbeing said: "Dudley Council offers a wide range of exercise activities to help our residents stay fit and active.
"The boot camp session is great value for money and gives an all round workout."
Classes costs £3 per person per session or is free of charge for those holding a Lifestyles membership at Dudley Council's leisure centres.
For more information call the Dell Stadium on 01384 812800 or visit www.dudley.gov.uk/sport


text:
dig (one's) own grave(redirected from digging my own grave)
dig (one's) own grave
To do something that has or will have negative consequences that are easily able to be foreseen. If you don't turn in your project, you're digging your own grave. There's no way you'll get a decent grade without it! I'm afraid I'm digging my own grave by turning down the promotion.


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Safety and Effectiveness of Azidothymidine (AZT) in HIV-Positive Patients With Hemophilia
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- No Study Results Posted
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- How to Read a Study Record
The purpose of this study is to see if giving azidothymidine (AZT) to HIV-positive patients with hemophilia is safe and if it is effective in lowering HIV levels and boosting the immune system.
HIV infects and inactivates certain blood cells that are part of the body's immune system. The damage to the body's immune system can result in unusual infections and/or unusual forms of cancer. A large percentage of hemophiliacs are HIV-positive and there is a clear risk for the development of AIDS in these patients. AZT may be effective in lowering HIV levels and boosting the immune system but its side effects are not understood in these patients.
|HIV Infections Hemophilia A
|Drug: Zidovudine
|Phase 1
|Study Type:
|Study Design:
|Masking: None (Open Label)
Primary Purpose: Treatment
|Official Title:
|A Phase I Trial to Evaluate Azidothymidine (AZT) in the Treatment of HIV Infections in Patients With Hemophilia
|Estimated Enrollment:
|Study Completion Date:
|March 1989
There is a clear risk for development of AIDS in hemophilic patients. AZT administration has been shown to inhibit HIV replication in vitro. Patients taking AZT have experienced fewer opportunistic infections and improvements in measures of immunity. The most common laboratory abnormalities observed with AZT are hematologic. However, the clinical and laboratory toxicity of AZT remains poorly understood in hemophiliacs. Hepatitis and liver dysfunction are more common in this population compared to other groups at risk for HIV infection. Because AZT is largely metabolized in the liver, drug pharmacokinetics needs to be evaluated in this patient population.
Both hemophiliacs and non-hemophiliacs take AZT for a period of 12 weeks. The first dose is administered intravenously. AZT is then given orally every 4 hours while awake (5 doses per day). Patients are evaluated by physical examinations and laboratory assessments. These include HIV culture of blood and leukocyte counts, lymphocyte counts, and lymphocyte subsets measured at study entry and every 4 weeks thereafter. Patients are hospitalized for pharmacokinetic studies at study entry and at Weeks 6 and 12. Each of these studies involves both intravenous and oral administration within 48 hours of one another. Blood is sampled at 0, 0.5, 1, 2, 3, 4, 6, 8, 10, and 12 hours after each administration and urine is collected every 2 hours for 12 hours.
|Ages Eligible for Study:
|12 Years and older (Child, Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria
You may be eligible for this study if you:
- Are HIV-positive.
- Have a bleeding disorder such as hemophilia A or B, a lack of factor VIII (a blood clotting factor), or severe von Willebrand's disease.
- Will be available for follow-up for at least a year.
- Are at least 12 years old (consent of parent or guardian required if under 18).
- Are willing to use an effective method of birth control during the study.
Exclusion Criteria
You will not be eligible for this study if you:
- Have a life-threatening opportunistic (AIDS-related) infection or AIDS-related symptoms.
- Have taken certain drugs within 30 days prior to study entry including chemotherapy and interferon.
- Are taking acetaminophen or drugs containing acetaminophen.
- Are pregnant or breast-feeding.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00000705
|United States, New York
|SUNY / Erie County Med Ctr at Buffalo
|Buffalo, New York, United States, 14215
|Univ of Rochester Medical Center
|Rochester, New York, United States, 14642
|Study Chair:
|Richard C. Reichman
|Responsible Party:
|National Institute of Allergy and Infectious Diseases (NIAID)
|ClinicalTrials.gov Identifier:
|NCT00000705 History of Changes
|Other Study ID Numbers:
10993 ( Registry Identifier: DAIDS ES Registry Number )
|Study First Received:
|November 2, 1999
|Last Updated:
|August 4, 2014
Keywords provided by National Institute of Allergy and Infectious Diseases (NIAID):
Drug Evaluation
Hemophilia A
Additional relevant MeSH terms:
HIV Infections
Acquired Immunodeficiency Syndrome
Hemophilia A
Lentivirus Infections
Retroviridae Infections
RNA Virus Infections
Virus Diseases
Sexually Transmitted Diseases, Viral
Sexually Transmitted Diseases
Immunologic Deficiency Syndromes
Immune System Diseases
Slow Virus Diseases
Blood Coagulation Disorders, Inherited
Blood Coagulation Disorders
Hematologic Diseases
Coagulation Protein Disorders
Hemorrhagic Disorders
Genetic Diseases, Inborn
Molecular Mechanisms of Pharmacological Action
Reverse Transcriptase Inhibitors
Nucleic Acid Synthesis Inhibitors
Enzyme Inhibitors
Anti-Retroviral Agents
Antiviral Agents
Anti-Infective Agents
Anti-HIV Agents
ClinicalTrials.gov processed this record on September 21, 2017


text:
Winter 240 Sottozero Serie II (Winter Tyre)
Tread Type:
How many tyres do you need?
Customer Comments
No customer comments have been left for this tyre yet.
Customer Ratings
Number of ratings: 1
- Car feels better to drive:
- Would buy again:
- Value for money:
- Overall rating:
- Performance winter tyre.
- Designed to offer superb traction in winter conditions.
- Offers superb performance in both dry and wet conditions.
- Asymmetric tread provides two characteristics, the inside is designed to provide snow traction whereas the outside is designed to improve performance in wet and dry conditions.
- Superb stability.
- Improved comfort thanks to reduced noise levels.


text:
Hybrid Capture Test on Mobile Unit Program to Improve Cervical Cancer Screening in Brazilian Rural and Remote Areas (careHPV)
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- No Study Results Posted
- Disclaimer
- How to Read a Study Record
This study evaluates the women cervical samples through molecular tests in order to:
1. Deploy the test careHPV (hybrid capture test) in mobile unities of the Barretos Cancer Hospital to evaluate their performance;
|Cervical Cancer Squamous Cell Human Papilloma Virus Infection Human Papilloma Virus-Related Carcinoma Prevention
|Early Phase 1
|Study Type:
|Study Design:
|Time Perspective: Prospective
|Official Title:
|CareHPV - Hybrid Capture Test on Mobile Unit Program to Improve Cervical Cancer Screening in Brazilian Rural and Remote Areas
- HR-HPV presence in the studied population. [ Time Frame: Up to 24 months ]
- The meaning of HPV presence relating with the conventional screening test (Papanicolaou smear), and the pattern of setting cervical lesion (biopsy). [ Time Frame: Up to 12 months ]
Biospecimen Retention: Samples With DNA
|Study Start Date:
|March 2012
|Study Completion Date:
|February 2014
|Primary Completion Date:
|December 2012 (Final data collection date for primary outcome measure)
Pap sampling
Women who have undergone Pap sampling and HPV and cytology analysis. The samples will be collected in Mobile Units and Non-Mobile Units.
Detailed Description:
Step1: Ambulatory samples First of all the careHPV cervical sample will be collected in specifically tubes, after this, make the cervical sample SurePath collect. Each patient will have two cervical samples. In this moment will be collected 2,000 samples at the Gynecology Department of Barretos Cancer Hospital and the women who be attended in the mobile unit of Barretos surrounding.
Sample1: careHPV The collect will be randomized where 1000 will be collected by the doctor and 1000 by self-sampling. The patient will be oriented by nurse with illustrative material. The self-sampling will be realized like the manufacturing protocol (Qiagen Inc., Gaithersburg, MD).
The cervical sample to cytology (SurePath) will be realized by doctor like a complementary test.
The conditions to store the samples are 15˚C to 30˚C by 2 weeks; 2˚C to 8˚C by 4 weeks; or -20˚C by 2 months to research.
Sample2: SurePath® cytology The cervical sample will be realized like the manufacturing protocol, by doctor. The lamina will be prepared like the equipment manufactory (Becton, Dickinson and Company). The cytological findings will be classifieds like the Bethesda system.
The positives women in careHPV/cytology and the negative careHPV but positive cytology (ASC-US+) will be referred to do the colposcopy (or biopsy) at the Barretos Cancer Hospital.
Step2: Mobiles Unities Samples This step will be collected 3,000 samples to careHPV test and SurePath cytology like a complementary test. The self-sampling won't be made in this step.
The samples will be analyzed in the own mobile unit, during the cities visited. The units involved in the project are that attended Mato Grosso, Goiás, Minas Gerais and Rondônia states, because the significantly number of population assisted.
Step3: HPV genotyping All the positives cases to careHPV test will be submitted to identify the HPV types, then realized at the Molecular Oncology Research Center in the Barretos Cancer Hospital.
|Ages Eligible for Study:
|Child, Adult, Senior
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
|Sampling Method:
|Non-Probability Sample
Inclusion Criteria:
- Any women who come to do the Papanicolaou test at the Barretos Cancer Hospital and in the mobile units on the remote Brazilian areas.
Exclusion Criteria:
Please refer to this study by its ClinicalTrials.gov identifier: NCT01539668
|Barretos Cancer Hospital
|Barretos, São Paulo, Brazil, 14.784-400
|Barretos Cancer Hospital
|Barretos, São Paulo, Brazil, 14784-400
|Principal Investigator:
|Adriana T Lorenzi, MSc
|Study Director:
|Adhemar Longatto-Filho, PhD
|Barretos Cancer Hospital
|Responsible Party:
|Adhemar Longatto-Filho, Coordinator, Barretos Cancer Hospital
|ClinicalTrials.gov Identifier:
|NCT01539668 History of Changes
|Other Study ID Numbers:
|Study First Received:
|January 23, 2012
|Last Updated:
|February 25, 2014
Keywords provided by Adhemar Longatto-Filho, Barretos Cancer Hospital:
Cervical Cancer
Secondary prevention
Additional relevant MeSH terms:
Uterine Cervical Neoplasms
Virus Diseases
Papillomavirus Infections
Uterine Neoplasms
Genital Neoplasms, Female
Urogenital Neoplasms
Neoplasms by Site
Uterine Cervical Diseases
Uterine Diseases
Genital Diseases, Female
Neoplasms, Squamous Cell
Neoplasms, Glandular and Epithelial
Neoplasms by Histologic Type
DNA Virus Infections
Tumor Virus Infections
ClinicalTrials.gov processed this record on September 21, 2017


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Here is an interesting plug-in. It's been available for PC for a few months but now that I can use it on my Mac it's worth a post here. It's a four channel drum machine plug-in that uses samples (PCM) and analog modeling. What's unique is the fact that this virtual machine has been "virtually" circuit bent!
You get four pads and individual outputs. Each pad allows the usual stuff like pitch, decay, tone, pain and volume. You also have chaos and chance sliders. Chaos sets is the amount of bending and chance sets how often chaos occurs.
Inspired by a combination of several old school beat boxes and the circuit-bending culture that revolves around cheap, and old, hardware musical instruments (such as the "toy†Casio and Yamaha keyboards of the 80s), Broken Drum Machine brings the lively, "ever changing", circuit-bent drum machine sounds to your DAW. – NUsoftting.com
You can use your own samples and even alter the GUI. When you do so you can save your changes in what NUsofting calls "Modpaks".
Here's a few audio samples of BDM in action from the NUsofting website:
This plug-in is 35 euros/about $50. There's more audio samples, demo songs and a demo version of BDM at the NUsofting website: click here


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Create an online review and share your thoughts with other customers
|Sort by:
5.0 5.0
4.0 4.0
5.0 5.0
Things I liked: This gun is fantastic!!! I was a bit leary about spending 1500 bucks for an air rifle, but if your serious about air guns you wont be dissapointed. This gun is at least as accurate as my condor but not quite as powerful, still very powerful. The side lever action is smooth and precise. The trigger is really nice out of the box and is fully adjustable, havent tried adjusting it yet, could use a little less second stage travel. Mounted a 4-16x50 leapears scope, i like these scopes, it's my 3rd one and they all are great particulary at less than a 100 bucks. I use the accushot high rings but probably could have used medium rngs. The gun is a bit heavy but has nice balance. The stock is gorgeous, no flaws at all in the wood. This gun is a show piece. I also had the 10 for 10$ test. 1st shot was 1080 10th shot was 1050, but that was with 11.4 gr pellets PA should use a heavier pellet more suited to the gun for their test. JSB exact jumbo heavy 18.1 gr seem to shoot very well, at 10 yrds. same hole time after time. The only reason i didnt giv this gun 5 stars for value was price, but that is splitting hairs, you get what you pay for. I would buy this again in a heartbeat.
Things I would have changed: Comes with a very very nice case, but with a large scope mounted wont fit. If case was 1 inch wider all would be good. But i can use it for 1 of my other air rifles.
What others should know: Regardless of the #2 loudness rating, this gun is pretty dang loud, not as loud as my condor, but not far behind. If condor is a 5 this gun is a solid 4.


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(VIDEO UPDATE, April 26) Lower watermelon volumes out of Mexico are buoying markets, and a slow start to the Florida deal could sustain them.
Markets will likely stay strong at least until Texas begins shipping volume, said Brent Harrison, president of Nogales, Ariz.-based Al Harrison Co.
"We're still seeing a lot of demand," Harrison said April 23. "Texas will be a factor soon, but they're not at this point. Supplies are still fairly light, and we're maintaining our prices."
Ward Thomas, owner of McAllen, Texas-based Majestic Produce Co., also reported strong demand in late April.
"The market seems to be holding strong, and I think it will stay that way because the pipeline isn't full," he said.
That pipeline will likely fill about May 10, when Texas begins shipping in volume, Thomas said.
Customers of Raleigh, N.C.-based Etheridge Produce LLC were asking for Florida watermelons in the second half of April, but Gordon Etheridge, the company's president, had to tell them to wait.
"We're really having a very poor season so far," Etheridge said. "It's either been cold or hot, back and forth. Everything in storage now is coming from Mexico or offshore."
Typically, Etheridge Produce is shipping from Florida by the week of April 22. This year, Etheridge said he'd have some Florida production by early May, but volume shipments wouldn't begin until the end of the month.
On April 23, the U.S. Department of Agriculture reported prices of 22 to 24 cents per pound for 24-inch bins of 35- and 45-count red seedless watermelons from Mexico, up from 22 cents last year at the same time.
Pollenization issues early in the Mexican watermelon deal contributed to lower yields, which were still being felt in the second half of April, Harrison said.
Quality, however, was very good, and fruit was traveling well, Harrison said.
Some Texas shippers were expected to begin shipping watermelons grown under hoops about April 27-28, but volumes wouldn't likely come until early May, Harrison said.
Al Harrison Co. expected to begin its Texas and Arizona deals in earnest around Memorial Day. The company's domestic deals will likely run through August, Harrison said.
Arizona and Texas growers reported good growing conditions in April, Harrison said.
Majestic began shipping watermelons from Texas's Rio Grande Valley the week of April 15, Thomas said.
The company reported a wide range of sizes, high sugar levels and excellent overall quality, though it was too early to gauge what yields would be, he said.
Thomas said Majestic would continue to bring in Mexican watermelons through Nogales "as long as the market warrants."


text: I was on a FaceTime call with a friend tonight, who just got his iPhone 4, and he told me I could drag the video of myself around on the screen. That's awesome! All you do is touch it and drag it to either of the four corners. Let us know of any other tips in Facetime!


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Watermelon On A Stick
Watermelon on a stick, isn't that the coolest idea? No cooking required for this one! Sometimes it's the simplest things that make the best desserts.
Take sweet watermelon for example, the perfect summer dessert as is – but add a stick to it and you have a fun way to present it at your backyard parties. I saw this on Real Simple and I knew I wanted to share this idea with you all. My husband thought it was brilliant as we happily enjoyed this after dinner.
Note: not a recipe, simply a fun idea I thought I would share. No cooking requires : )
Watermelon On A Stick
- fresh watermelon, sliced about 1-inch thick
You will need:
- posicle sticks
- sharp knife
Cut watermelon into pizza shaped wedges.
Insert a knife into the center of the rind and push the stick into the hole.
Enjoy and stay cool!


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Each day in November—leading up to the winter meetings—Sporting News will analyze the offseason to-do list of a major league team. Today: the St. Louis Cardinals.
No Albert Pujols? No Tony La Russa? No problem for rookie manager Mike Matheny and the Cardinals, who came within one win of reaching the World Series. With a roster stocked with homegrown position players and power righthanders, the Cardinals' 2013 shapes up even better. This offseason will be about filling holes much less significant than the ones left by Pujols and La Russa last year.
When lefty reliever and middle infielder comprise your shopping list, you should be able to enjoy some of the "off" in the offseason. But maybe not when you've had as much trouble finding a reliable lefty as GM John Mozeliak has.
The Cardinals haven't had a consistent lefty since Trever Miller in 2009. Marc Rzepczynski was supposed to be the guy, but he struggled so much in 2012 that you wonder if he will return in 2013. Because they have an abundance of promising righthanders, the Cardinals might carry only one lefty in their bullpen. If Mozeliak signs a veteran such as Randy Choate or Jeremy Affeldt, Rzepczynski would become expendable.
The team's plan to shore up the middle infield likely won't be determined before the winter meetings because of shortstop Rafael Furcal's health. Furcal has another year on his contract, but an elbow injury that ended his 2012 has him uncertain for 2013. Rookie Pete Kozma appeared to have boosted his chances of taking over the position with a strong September, but after rough moments in the playoffs, he is no longer a sure bet to make the roster.
If the Cardinals believe Furcal will be ready, they could shop for a free agent who could back up short and compete with Daniel Descalso for the second-base job. Jeff Keppinger has been mentioned as a possibility.
If Furcal's recovery stalls, Mozeliak would be more likely to explore a trade market that includes shortstop Yunel Escobar, who has worn out his welcome with the Toronto Blue Jays. Another possibility? The Cards are said to have significant interest in Asdrubal Cabrera, if the Cleveland Indians decide to peddle him.
The back of the rotation is the only other unsettled area, but no shopping will be required to fill it. The Cardinals, in fact, have so much depth that 18-game winner Lance Lynn has been told he doesn't have a secured spot in the rotation. Those who do are Adam Wainwright, Chris Carpenter, Jake Westbrook and Jaime Garcia, if his left shoulder is OK.
The club is so deep in starters that Mozeliak isn't even planning to discuss a return with free agent Kyle Lohse, the team's winningest pitcher over the past two seasons.
Lance Berkman also is expendable because of younger (and less expensive) in-house talent. The same goes for two of the longer-tenured Cardinals, reliever Kyle McClellan and utility man Skip Schumaker.
The club has bid farewell to Mark McGwire, who left for the Dodgers after three years as Cardinals hitting coach.
Regardless of what they do this offseason, all the Cardinals need to contend in 2013 is good health. That, however, has been difficult to come by the past two years.
Toronto Blue Jays Hot Stove Report.
Also on the stove
— Cincinnati Reds | Washington Nationals | San Francisco Giants |
— Boston Red Sox | New York Yankees | Houston Astros | Cleveland Indians | Detroit Tigers |


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A TEENAGER has been arrested for alleged kidnapping, a sexual offence and assault while the subject of an interim anti-social behaviour order, magistrates heard.
But Natalie Harvey, 18, had not caused trouble in Burnley town centre and the accommodation project which she has been kicked out of, the court was told.
Harvey was made the subject of a temporary ASBO in November, which barred her from Charter Walk shopping centre, Burnley Central library, Elizabeth Street and the Stepping Stone project on Westgate.
Pc Mark Driver, who runs the police division's anti-social behaviour unit, said he had spoken to Christine Greenwood, a case worker at Stepping Stones, who said residents were now able to return home from work or college without encountering disturbances, said to involve Harvey.
And the officer said there had been no complaints made by town centre shops regarding Harvey causing trouble there.
But magistrates heard she had been arrested on suspicion of kidnapping and a sexual offence, assault and breaching her ASBO during the court proceedings.
Harvey, now of Parkinson Street, Burnley, will now face a full ASBO hearing before Burnley magistrates on February 28.
And a 17-year-old from Burnley, also the subject of similar interim ASBO and restrictions, will also face a full hearing.
The pair were also told that they must not use abusive or threatening behaviour, or hand gestures, anywhere in the borough, until their next hearings.


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Moderators: Timko, Fritz, Solty, Booter, Blake_T, Frank Delicious
Frank Delicious wrote:Every groove is a unique snowflake of suck.
Jeronimo wrote:I've never had a situation that required a full fledged pants changing but I know the "shart" all too well... It's always the one that before laying it makes me say "Hmmmmm... that feels like it's going to be a warm fart with a lot of pressure behind it". Rule of thumb, if you have to fart but you think you'll try to use your anus like a valve to limit the speed and intensity of the fart, don't. It's not a fart, it's shit.
zenn9 wrote:Is this really a thread?! LMFAO
Ryen91 wrote:I am pretty sure I am more intelligent then you think and have allot more knowledge then your post might suggest.
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HEALTHIER eating is on the menu for children at St Peter's School in Williton after a Change 4 Life Day.
Pupils and parents learned all about healthy eating by having a go at cooking their own and a competition for the healthiest lunchbox.
The day was a follow-up to the Tesco Farm to Fork visits. Professor Salt, Sugar and Lard conducted experiments with everyday foods at the Change 4 Life Day.
A spokesperson from the school said: "The children and parents all enjoyed themselves and learned a lot.
"The children have really embraced the fact that they can make a smart swap and still enjoy their food."


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Aruba Women Hoodies are an Idakoos specialtiy! Idakoos has many things to offer. Whether you want to get a Aruba Hoodie for a special occasion, give a Aruba Sweatshirt as a present or need to represent with a funny Aruba Women Hoody during Holidays or Family and Friends get-togethers, Idakoos is sure to have the right Aruba Hoodie for you! Even if it turns out you can't find the right Aruba Hooded Sweatshirt with the perfect design for your mother, father or children (or friends!); Idakoos offers all of its men's women's and children's Aruba Women Hoodies as Aruba Women Hoodies. Personalize any Aruba Hooded Sweater the way you want to ensure the perfect gift.
Showing 1 - 24 of 426 Women Hoodies


text:
Macon coding bootcamps are immersive training programs that help you transition into a tech career. Switchup has compiled verified alumni reviews for courses around the world that range from 1 to 5 stars. Right now in Macon there are no coding bootcamps - checkout nearby cities in our full coding bootcamp directory.
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- When:
- Location:
- Gordon Plaza
- Description:
Join your colleagues for some friendly competition in a game that all can play - cornhole! We will be outside (rain site is the Recreation Center basketball courts) every Tuesday from 12-1pm, July 8 - August 12, 2014. Pre-registration is not required, however if you bring the same teammate for at least two weeks of competition, you will be eligible to compete in the final playoff bracket.
Drop by and check it out! Please arrive no later than 12:05, so that teams have enough time to get at least one full game in.
We hope to see you there!
- Contact Name:
- Sarah Shouvlin
- Contact Email:
- firstname.lastname@example.com
- Contact Phone:
- 410.837.4090
If you need accommodations to participate in this event, please contact the person listed above at least 10 days prior to the event.


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Manchester City officials on Saturday denied a Bloomberg News report that the wealthy English Premier League champions plan to spend $100 million to purchase a Major League Soccer expansion team in New York City.
"Manchester City (owners) are not buying an MLS club," it said in a statement to the UK's Press Association.
Bloomberg cited three unnamed sources Friday in its story, which claimed that Man City owner Sheikh Mansour bin Zayed Al Nahyan, a member of Abu Dhabi's ruling family, was "close to being awarded" the rights to operate the club that MLS hopes to launch in 2016.
The league is working diligently to construct a privately-financed, 25,000-seat stadium in Flushing Meadows-Corona Park in Queens. Man City officials refused to comment when reached by Bloomberg on Friday and then chose to release its statement once the initial story gained traction.
According to the initial report, the new MLS team was set to be called New York City Football Club. In addition, former Manchester United and L.A. Galaxy star David Beckham reportedly was contacted regarding a role in the organization. He holds an option to own a new MLS team outside New York City at below the market rate. The Montreal Impact, which began play this season, paid $40 million to join the league in 2010.
MLS officials have said that there are multiple potential ownership groups interested in a New York City team. Only the New York Cosmos, who are set to begin play in the second-tier NASL next year, have expressed their interest publicly.


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Why the Internet Hurts Wrestling
by, 05-16-2012 at 09:12 PM (5759 Views)
It is infuriating to be watching a Raw match and then the commentary gets interrupted because Michael Cole has to tell us what is trending on Twitter. The WWE literally wants to interrupt a match so that we know that #FutureEndeavored is trending on a website. Wait wait, i want to know what is going on in the match...
The internet is hurting the business in so many ways. To start, WWE is wasting its time trying to get us to "like" them on Facebook or follow them and their wrestlers on Twitter. So instead of an interesting wrestling fact, we get some stupid fact like:
"John Cena has more Twitter followers then the NFL, NBA, and President Obama combined!"
When i see stupid stuff like this, I ask myself why the fuck was the internet invented.
Ahh, but where would we be without the internet. Well, we would be nowhere. The internet is everywhere, and the digital disease has now spread to the wrestling business. Forget the stupid facts after commercials, we see twitter hash tags all the time during Raw and Smackdown. They do pre-PPV matches on YouTube. They spend more time updating wrestler profile pages on WWE.com than developing its character as a wrestler. People, this shit is so bad, we don't even need to watch SmackDown anymore! We go to the INTERNET to find out what is going to happen 4 days before Friday. We find out about creative plans for wrestlers days before the next show. We know instantly as they happens before they want us to know when it happens.
And then you guys wonder why you are getting bored of wrestling. Its because we know what the fuck is going to happen in advance.
My favorite of all reasons to hate the equation "wrestling+internet" is the impact it has on the wrestlers themselves. I can just give you 3 names: Scott Steiner, Kurt Angle, Matt Hardy. I'm not going to elaborate too much, because we all go to this site 24/7. Assuming that, you know how much of idiots these guys are. They constantly put stupid shit on Twitter. Its getting so escalated, that Eric Bishoff and Hulk Hogan are threatening legal action because Steiner can't keep his mouth shut. I understand that what he says is hilarious. But then again, he keeps wondering why TNA got rid of him in the first place.
The internet just doesn't make stuff personal anymore. It is way to public. People feel since no one sees them physically that they can share their personal feelings. What they don't understand is that once you click "send", THE WORLD sees. Its not just the people around you. Everyone can see what you think of, and most times, there are serious consequences. We find out about spoilers and all this stuff that should be concealed. But in all honesty, it ruins the surprise that comes with wrestling. When was the last time we were like "WOAH I did not see that coming." Sadly, I don't.
I'll be completely honest: I don't have a fix for this. I won't say "Oh well they didn't have internet in the Attitude Era" or make some other reference that will piss people off because honestly wrestling would be fine, Reality Era and everything, if they didn't have the internet. Also, there is no reason to fix this because: 1) we all love coming to this site anyways 2) It would take away the thing that people who make this site possible love to do. At this point, you cant stop the internet because its everywhere. We just have to deal with it.
At the end of the day, we all love our wrestling. Internet or not, our love for the business will never change.
But the question comes up in my mind: is there a way to keep secrets away from the internet in the wrestling community?
**Thanks for reading guys. I like to end my blogs with a little question, they usually draw creative thinking from comments ^__^**
DISCLAIMER: I am in no way trashing this site or the internet in general. I love the site, and am a frequent visitor. I also am not encouraging the staff here to change. You guys do an excellent job, keep it up!


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U.S Army Capt. Michael Frey and his wife Megan have been together through all 3 of his deployments, first while they were dating, then while they were married and now, with newborn twins!
He delayed his deployment so he could see the birth, but left 6 days later for Kunar province in Afghanistan.
They've stayed in touch through Skype.
Tell us about a military man or woman in your life on our special Salute to Troops iReport assignment page: iReport.com/Salute. You could see your hero on Morning Express with Robin Meade!


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SAN BERNARDINO, Calif. — Stater Bros. on Wednesday disclosed a more than 4% decrease in sales for fiscal year 2010.
The California supermarket chain said sales for the fiscal year ended Sept. 26 were $3.61 billion, down from $3.77 billion in fiscal year 2009. Sales for the fourth quarter also experience a decline, dropping to $897.4 million, or 3.15%, since the year-ago period.
Net income for Stater Bros. totaled $24.6 million for the 2010 fiscal year, compared with $34.8 million in the 2009 fiscal year. The results for the fourth quarters of fiscal 2010 and fiscal 2009 were net income of $5.9 million and $5 million, respectively.
Stater Bros. leader Jack Brown said that while the chain is facing tough economic and competitive pressures, the retailer is "committed to controlling costs as [we] weather the effect of these economic times."


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Donors can play a crucial role in strengthening the ability of civil society organizations (CSOs) across Africa to organize, advocate, raise awareness, act as watchdogs, and provide vital services. However, the ability of CSOs to make a true impact depends not only upon their own organizational capacity and financial viability, but also upon such external factors as the legal environment in which they operate and the infrastructure supporting them.
On December 10, the United States Agency for International Development (USAID) and the Program on America and the Global Economy will co-host a panel discussion on Secretary Clinton's Economic Statecraft agenda at the Woodrow Wilson Center in Washington, D.C. USAID Administrator Rajiv Shah will make opening remarks at the inter-agency panel that will focus on, "Economic Statecraft: Developing Partnerships with the Private Sector."
Today, the U.S. Agency for International Development (USAID) launched Making All Voices Count: A Grand Challenge for Development, a unique multi-donor partnership to support innovative, next-generation solutions that use web and mobile technology to grow the global movement for open government, transparency and accountability.
The United States Agency for International Development (USAID), together with the World Wildlife Fund – U.S. (WWF), is launching a unique four-year water security and sustainable development project across Asia in which snow leopard conservation plays a key role.
On December 5, the United States Agency for International Development (USAID) will host a unique event with leaders from across government, civil-society, and the technology sector to unveil Making All Voices Count (MAVC): A Grand Challenge for Development - a unique multi-donor partnership to support innovative solutions using web and mobile technology to grow the global movement for open government, transparency and accountability.
Today, United States Agency for International Development (USAID) Administrator Rajiv Shah announced the launch of the Agency's first-ever policy and program guidance on Building Resilience to Recurrent Crisis during an event in Washington DC. Dr. Shah was joined by a distinguished panel of guests, including His Excellency Ambassador Elkanah Odembo, Kenyan Ambassador to the United States; The Honorable Jim McGovern (D-MA); Gayle Smith, Special Assistant to the President and Senior Director at the National Security Council; David Beckmann, President of Bread for the World; Neal Keny-Guyer, CEO of Mercy Corps; and Carolyn Woo, President & CEO of Catholic Relief Services.
Today, the United States Agency for International Development (USAID) signed a Memorandum of Understanding (MoU) with the European Union (EU) to support implementation of the Kimberley Process Certification Scheme (KP), which combats the trade in conflict diamonds. The MoU signifies the desire of USAID and the EU to collaborate and co-fund the implementation of USAID's Property Rights and Artisanal Diamond Development (PRADD) program, which aims to assist countries with strengthening their compliance with the KP.
Today, the Kimberley Process Certification Scheme (KP), which was established to end the trafficking of "conflict diamonds," adopted the Washington Declaration that more formally incorporates development objectives into KP implementation.
On World AIDS Day, we join the global community to pay tribute to the more than 34 million people living with HIV/AIDS worldwide and reaffirm our commitment to helping those in need. It is a time of remembrance, as well as an opportunity to reflect on how far we have come and the steps we must take today to realize an AIDS free generation.
The United States Agency for International Development (USAID) will release its new Policy and Program Guidance on Building Resilience to Recurrent Crisis on December 3.
Today, the United States Agency for International Development (USAID) launches the contest phase of the Countering Trafficking in Persons (C-TIP) Campus Challenge—a technology contest where students can submit new ideas and innovative ways to end modern slavery at www.challengeslavery.org. The contest will be open from November 28, 2012 to January 8, 2013. USAID will award one first place prize of $5,000 to the top entry, and $2,500 to one or more runner-up entries. Additionally, winners will be invited to showcase and discuss their ideas with USAID and various implementing and donor partners. The contest asks students to address how technology can be part of a potential solution to the various challenges related to CTIP, whether concerning slavery in product supply chains, trafficking in conflict and crisis-affected areas, child sex tourism, building a global CTIP movement, ending forced child labor, countering the business model of TIP or raising awareness among potential victims.
The United States Agency for International Development (USAID) launched the Higher Education Partnerships to Support the U.S.-Burma Commitment to Democracy, Peace and Prosperity, furthering President Obama's call to "extend a hand" to Burma in its progress toward democracy.
From November 25th-27th Dr. Rajiv Shah, Administrator of the U.S. Agency for International Development (USAID) will travel to Turkey where he will meet with senior officials to discuss the ongoing humanitarian crisis in Syria and assistance for those affected by the crisis.
The U.S. Agency for International Development today announces its commitment to support the operations of the Migration and Development Fund (MDF) administered by the African Development Bank. This commitment to the MDF is part of USAID efforts to work more closely with diaspora communities to promote their engagement in the development of their countries of origin.
The U.S. Agency for International Development (USAID) announced additional support towards INTERPOL's Project Predator to support the South Asia Wildlife Enforcement Network (SAWEN) in protecting wild tigers.
During his visit to Burma, President Barack Obama announced a joint US-Burma partnership to advance democratic reform, and lay the groundwork for a peaceful and prosperous future for Burma. The President also announced $170 million dollars over the next two years to support this effort. The Partnership aims to strengthen democracy, human rights and rule of law; promote transparent governance; advance peace and reconciliation; meet humanitarian needs; and provide economic development that can improve the health and livelihoods of the people of Burma.
Today, the United States Agency for International Development (USAID) launched three mobile phone games through its public-private partnership with the Half the Sky Movement. As part of the Agency's continued support of gender and family issues, the games are designed to increase global awareness and bring about social change in the areas of health, gender equality and empowerment.
Feed the Future's new Partnering for Innovation program formally launched today at the Ronald Reagan International Trade Center in Washington, DC. The program, supported through the United States Agency for International Development (USAID) and Fintrac Inc., aims to engage the private sector and put transformational technologies into the hands of smallholder farmers in developing countries to quickly and sustainably improve their productivity and incomes.
The U.S. Agency for International Development (USAID) announces today the launch of its Higher Education Solutions Network (HESN)— a new groundbreaking partnership with seven top American and foreign universities designed to develop innovative solutions to global development challenges.
United States Agency for International Development (USAID) today announced the release of USAID's Policy on Youth in Development, the first Agency-wide guidance to recognize young people as a driving force in global development and promote youth participation as partners and leaders. The policy's guiding principles support USAID's efforts to mainstream youth in development, carry out effective programs, and elevate youth participation throughout the world.
With more than half of the global population under the age of 30 and a majority residing in developing countries, USAID's release of the policy reinforces that young people must be a central focus when developing country strategies and recognizes the need to support, prepare, engage and protect youth today as well as harness the energy and creativity of young people for positive change.
Last updated: September 22, 2017


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East Molesey-based Old Tiffinians are on a seemingly unstoppable march towards the London leagues.
The Tiffin School old boys secured a 10th straight Surrey Divison One win of the season with a 43-5 triumph at home to bottom club Old Walcountians.
Tiffs top the table by 11 points from tomorrow's hosts Old Tonbridgians.


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My 104-year-old friend Ardis MacGregor died last week in her Washington, D.C.-area condominium, surrounded by family, friends and a caregiver who has offered devoted service for the past eight years.
I've been blogging about retirement for four years and once in awhile, I have mentioned Mrs. MacGregor as a good example of someone who grew old gracefully. She got a kick out of that.
I'm 62 and at an age when most people are thinking seriously about hanging up their work boots if they haven't already done so. Mrs. MacGregor offers a good reason to rethink that retirement planning mindset because she lived 42 years beyond that milestone.
Mrs. MacGregor was smart, and she did a few basic things during her life that helped make her later years comfortable. They are things any of us could do to improve our prospects.
Get ready for a long life. Mrs. MacGregor and her late husband Gordon ran a business and saved and invested the proceeds so they would have security in their later years. After her husband died nearly 40 years ago, she managed her own money, although her banker son offered advice. The last few years, she hired around-the-clock, live-in caregivers -- a very expensive proposition which she paid for without assistance from family or the government. It helped that she was happily frugal, and it didn't hurt that her husband left her two oil wells.
Have a purpose. At 75, Mrs. MacGregor took up competitive ballroom dancing. Her trophy case was packed with awards for waltz, rumba and tango. Even at her 100th birthday party, while she was no longer competitive, she could still cut a rug with her son and grandson.
Make health care a priority. Up until a few months ago, Mrs. MacGregor was still riding her exercise bike daily. She nurtured her relationships with physicians and spent the extra money required for a boutique health insurance plan that allowed her easy access to top doctors, including an option she used often to email her doctor -- and expect a rapid response -- whenever she had a concern or question.
Keep family close. In the weeks before she died, Mrs. MacGregor was busy writing her memoirs, preparing an illustrated family history for the fourth generation of MacGregors, who may not remember their great grandmother, but who will undoubtedly appreciate her legacy.


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- Description
The Hayabusa Logo hat is designed with the Hayabusa name/logo in the center.
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text: WHIRLPOOL ROOM WITH FIREPLACE. 20% OFF WHEN TWO (2) CONSECUTIVE NIGHTS ARE BOOKED. This special includes a complimentary bottle of wine and elegant candlelight breakfast at fireside. There are 7 whirlpool rooms with fireplaces so book early to avoid disappointment. Find your room www.marketstreetinn.com and call direct 217-824-7220 to receive 20% discount. Such a sweet deal for any weekend or weekdays during the entire month


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New Pirate Minimates get a ship...
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Diamond Select Toys announces that their latest Minimates MAX toy line - Calico Jack's Pirate Raiders - have set sail exclusively at Toys"R"Us. Calico Jack and his crew have been captured in a series of two-packs, along with the evil Captain Charles Vane and his crew of zombie pirates. On sale now, the initial assortment includes:
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Corbett lottery maneuvers winning no fans in Pa. Legislature
Gov. Tom Corbett's plans to privatize the Pennsylvania Lottery may be well within the law, but his approach may also be hurting his relationship with state lawmakers.
Just two months ago, the governor was resolving to change the way his administration works with the General Assembly.
"I know we need to communicate better, and I think we are. We're in that process," he said during a November interview.
Now some state lawmakers are balking at what they say is a dearth of information from the administration about the lottery deal.
Corbett says evaluating and choosing private bids on the lottery is a role for the executive branch -- not something that should require lawmakers' input.
"So, what you're saying is the Legislature has the ability to say, we like this bid or don't? That's not the way it works," Corbett said Wednesday. "Any bids that we put out, purchase of cars, purchase of goods and services, and that's what this is -- this is a service."
Still, lawmakers have protested that the expansion of lottery games planned by British firm Camelot Global Services should only come with legislative approval.
Corbett says he'll make a final decision on the deal by the end of Thursday -- days ahead of a state House hearing scheduled to vet the proposal.
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I can't get enough of these wonderful wedged heels!
I think it has something to do with being a new mom and wanting to be current but not totally sacrifice comfort.
Which are your favorites?
from Need Supply Co, Nasty Gal & UO.
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San Francisco 49ers to play Broncos in London in 2010
By Daniel Brown, firstname.lastname@example.com
Posted: 01/15/2010 09:07:07 PM PST
Updated: 01/15/2010 10:29:40 PM PST
One of the 49ers' home games next season will take place more than 5,300 miles from home. The 49ers and the Denver Broncos will travel to London for a regular-season game Oct. 31.
Reacting to the announcement Friday, players and team officials said they are eager to play the role of international ambassadors.
"I've always wanted to go overseas, and now I get to go over with my teammates and play football," tight end Vernon Davis said in a statement released by the team. "I can't wait to go over there and show all of Europe what 49ers football is all about."
This marks the fourth consecutive season in which the NFL has held a regular-season game at Wembley Stadium, which holds about 84,000 fans for American football. The game will be played at 5 p.m. in London and will be broadcast by CBS at 10 a.m. Pacific time.
"London is a wonderful venue for two of the most storied franchises in NFL history to square off," said Jed York, the 49ers' president, in one of several prepared statements released by the team.
The 49ers have played at Wembley Stadium twice in exhibitions in 1988 against Miami and in 1992 against Washington. The 49ers also have played preseason games in Tokyo (1989 and '95); Osaka, Japan (2002); Berlin (1991); Barcelona, Spain (1993); and Vancouver, British Columbia (1998).
This is their second international appearance that will count in the standings: The 49ers played the Arizona Cardinals in Mexico City
in 2005, the first NFL regular-season game played on foreign soil.
The rest of the 49ers' schedule will be announced in April. They are expected to get a bye week after the London trip, which would allow extra recovery time after the demanding travel.
For now, the 49ers are just happy to get such a showcase.
"I am thrilled about the chance to represent the NFL internationally," coach Mike Singletary said in a prepared statement. "I have no doubt that our players will be ready to go. "
Linebacker Patrick Willis said: "I couldn't think of a better way to get to visit England than to go there doing something I love to do playing football."
In announcing the matchup, the NFL noted that the 49ers and the Broncos are among the most decorated teams in league history. The 49ers have five Super Bowl titles, and Denver has two.
The 49ers defeated the Broncos in Super Bowl XXIV in 1990.
The NFL said it will continue to explore adding a second game this season in the United Kingdom.
"For the past three years we have seen the extraordinary passion that exists for NFL football in the U.K.," commissioner Roger Goodell said. "We want to continue to build on that passion by strengthening our ties to our existing U.K. fans and creating new ones."
A 49ers spokesman said financial details of the arrangement still are being worked out. The 49ers are not expected to lose revenue by giving up a home date.
Season-ticket holders will be required to purchase only nine games: seven regular-season dates and two preseason games. The 49ers said season-ticket holders interested in attending the London game will get more information when the renewal process begins in a few weeks.


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Sephora Waterproof Mascara Reviews
Long LastingI love waterproof mascara in the summer, especially when it stays on like this one. This mascara not only makes your lashes look fuller and longer but it stays on even when you take a dip in the pool or are sweating in the hot sun. This is a great waterproof product. — 9 years, 3 months agoStef42678 | 500 reviews
DisappointingJust a plain boring mascara. Does nothing for my lashes. — 2 years, 10 months agoRealPrincessMel | 111 reviews
This review is: Helpful | Not helpful | Inappropriate | 0 of 0 people said helpful
Review subjectI wasn't impressed with this mascara. I HAVE to wear waterproof mascara because I live in a very humid climate & also suffer from allergies that make my eyes water. I bought this thinking it would be fantastic & quickly found that it wasn't. An hour into my day, I had raccoon eyes. Too bad, I love all the other Sephora makeup that I wear, — 5 years, 5 months agorenea_schindler_garza | 1 reviews
DescentThis mascara doesn't clump, but it barely brings out your lashes. — 5 years, 9 months agoShelby4Life | 2 reviews
Works for some, but not for meI have such thin lashes that this just didn't do it for me. I need more — 9 years agollsdogmom | 15 reviews
Great mascara!I love Sephora's Waterproof Mascara. Originally, I only bought this because I wanted a green mascara, but not only is the color fun and smudge-proof, it's light and it lasts! If you're expecting length, volume, or curl, this is not for you. This definitely lives up to its name and is great for such an inexpensive price. — 9 years, 1 month agoglor1a | 25 reviews
This review is: Helpful | Not helpful | Inappropriate | 0 of 1 people said helpful
Great MascaraI was a bit skeptical that this mascara wouldn't smudge thanks to the other "waterproof" mascaras I have used, but actually was pleasantly surprised! The mascara was light and dried quickly, unlike a lot of other brands I've tried. All in all, I'd say it's pretty good! — 9 years, 2 months agoatomicus18 | 1 reviews
This review is: Helpful | Not helpful | Inappropriate | 2 of 2 people said helpful
Miffed about this MascaraAfter I bought this mascara, I found out that I can't wear it everyday since it's waterproof. Bummer! — 9 years, 3 months agoteffers8464 | 71 reviews
works greatlove it goes on good and lasts just like it says. — 9 years, 3 months agojudycc20 | 113 reviews
really waterprooflasted 4 hours in the pool. — 9 years, 3 months agoitssmee | 8 reviews
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FOXBOROUGH, Mass.—When the New England Patriots made the move to acquire cornerback Aqib Talib from the Tampa Bay Buccaneers on Nov. 1, fans easily would have been forgiven for viewing the deal with skepticism.
In years past, the Patriots had success in taking on other teams' headaches, scoring big with the likes of running back Corey Dillon and receiver Randy Moss, earning coach Bill Belichick a reputation as a miracle worker within the talented-but-troubled set.
But more recently, folks in these parts watched in puzzlement as the Patriots took gambles last season on defensive lineman Albert Haynesworth and receiver Chad Ochocinco. Not so miraculous, those choices, as Haynesworth was cut in early November 2011 and Ochocinco caught 15 passes all season.
Now along comes Talib, who was serving a four-game suspension for failing a banned-substance test at the time of the trade, and whose litany of run-ins — with the law, with his own teammates and, yes, even once with a game official outside the Tampa Bay locker room — could fill a small notebook.
This had the potential to go down as another Patriots overreach. But, turns out there is a big difference between Talib and guys like Haynesworth and Ochocinco: Talib still can play.
As they prepare to line up in the AFC championship game against Baltimore on Sunday, there may be no player more instrumental in bolstering the Patriots' chances to return to the Super Bowl — and win it this time — than Talib. And he is happy to be along for the ride.
NFL conference title games
— NFC, San Francisco 49ers at Atlanta Falcons, 3 p.m. ET
— AFC: Baltimore Ravens at New England Patriots, 6:30 p.m. ET
— Fantasy Source matchups: 49ers-Falcons | Ravens-Patriots
— The Linemakers: Falcons favored | Matchup odds | News and notes
"Oh man, this is what you play football for," Talib said. "You don't play football to play 16 and go home. You play to get in the tournament and try to get the trophy. We're just going one week at a time, and Baltimore is on the agenda next."
First, a word about what Talib did last Sunday, in New England's 41-28 win over the Houston Texans at Gillette Stadium that set up the Ravens showdown. He lined up, one-on-one, against Andre Johnson, one of the league's top receivers, for nearly the entire game. Johnson wound up with eight catches for 95 yards, but considering the Texans threw 51 times as they tried to erase a big deficit, Talib actually held Johnson largely in check. Johnson's biggest gainer — a 22-yard catch in the middle of the third quarter—occurred when Talib was not defending him.
"The biggest thing when you play a guy like (Johnson) is to try a bunch of different things," safety and defensive captain Devin McCourty said. "I think you can't take away what Aqib did, going out there and just challenging him every play and being able to play one of the top receivers in the league. We did different things at different times, but most of it was just Aqib playing good defense."
That's been a critical change for the Patriots in the second half of the season, as they have bounced back from a ho-hum 5-3 start in which it looked like years of shuffling through shoddy combinations in the secondary would continue.
— Ravens vs. Patriots: One more time for Ray Lewis vs. Tom Brady
McCourty was struggling at cornerback, after having established that he was more comfortable at safety. Corner Kyle Arrington, too, was struggling. Injuries and inexperience at safety were killing the Patriots, with deep balls over the middle providing easy pickings for even so-so quarterbacks (almost one-fifth of Ryan Fitzpatrick's 16-game total passing yards came in two games against New England, after all).
But then the Patriots finally got Talib onto the field in Week 11. He gave them something the team had not had in years — a big (6-1, 205), rangy, athletic lockdown corner who can defend an Andre Johnson-type for a full 60 minutes. With rookie Alfonzo Dennard inserted (and playing well) at the opposite corner, the Patriots' entire secondary has gotten a facelift. McCourty has returned to safety, where he can oversee the entire backside of the defense. Arrington and Steve Gregory are in their comfort zones, playing against slot receivers in nickel packages.
With more confidence in the defensive backs, the linebackers and ends have had more freedom to be aggressive.
"Obviously it's great to get another veteran player on the back end, someone that has some excellent experience in the NFL and can really fit in the younger group and kind of really just blend into the guys that we have and fit the pieces," defensive coordinator Matt Patricia said. "(Talib) has done a real good job, really coming in and adapting to our system, learning the defense as we run it and the different coverages that we play and overall just been an excellent teammate really, kind of a guy that the other guys fit in with and get along with and obviously then compete and play hard with."
Indeed, Talib has brought an increased sense of attitude to a unit that lacked an identity for so long — yep, that was Talib jawing with Johnson after just about every play in which the two were entangled.
That will be important for the Patriots, who are going to need a solid overall performance from the secondary this week. While Johnson is the primary weapon for the Texans, the Ravens have Anquan Boldin, Torrey Smith and Jacoby Jones putting up good numbers for quarterback Joe Flacco. When the Patriots played the Ravens in Week 3, it was Smith who torched them for 127 yards and two touchdowns. In the Ravens' wild-card playoff win over the Colts, Boldin posted 145 yards. Talib will draw one of the two on Sunday.
Which makes him happy. "If you're a cornerback and you don't want to go after their best receiver, you're in the wrong business," he said.
So has Belichick done it again? Has he taken another bad egg and rebuilt him? Talib wouldn't quite put it that way. He's still adjusting to New England, still adjusting to his new team. Coming to work has been a lot more rewarding lately, that's all.
"It's a lot better," Talib said. "I wouldn't say simplified. I'd say it's a lot better. It's a lot better, getting to work for Mr. (Robert) Kraft, Coach Belichick. It's a lot better."


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Two Denver-based groups are set to protest against the Washington Redskins refusal to change its name and mascot.
Members of the American Indian Movement and Idle No More in Colorado will call on the football team to change its name at the Broncos-Redskins game on Sunday.
Members of the group say that the name is "racist" and "an insult to all indigenous peoples." They are also telling all Colorado news and sports journalists to banish the so-called 'R' word from their reporting; asking that local press such as The Denver Post and NBC's KUSA to call them "the team from Washington, D.C."
Both groups say that most American Indians consider the word to have a long racist history in the U.S.
Most recently, about 20 members from various Native American tribes protested outside Lambeau Field at the team's game against the Green Bay Packers.
In a news release, the group invited "all people of goodwill" to protest at the football game. Protestors will gather at Sports Authority Field at Mile High in Denver. Here are the details of the protest:
Sunday, October 27, 2013 • Denver, CO • Assemble 9-9:30 am, in front of Tivoli Student Union, Auraria Campus, 9th Avenue and Auraria Pkwy, downtown Denver. March from Tivoli to Sports Authority Field via Walnut Street. Rally at 10 am at Sports Authority Field, Visiting Team Entrance, by Parking Lot A, near Colfax Avenue and Mile High Stadium Circular. Rally to confront Washington team buses as they arrive for warm-up before the game.


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A Whitley man has been remanded in custody after appearing at Swindon Magistrates Court this morning charged with arson with intent to endanger life.
On Saturday, at around 3am, 57-year-old John Marshall's home, owned by Selwood Housing Association, in Eden Grove, Whitley caught light, the court heard.
The defence made no application for bail and the Crown Prosecution Service said he posed a serious risk to members of the public.
Marshall was remanded in custody, and the case will appear before Swindon Crown Court on Friday, February 14.


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The Fine Print:
We reserve the right to validate all price matches. Total price matched is the absolute total including shipping. Clearance product is excluded.
No promotions can be combined with any price matched item. This offer/guarantee may stop at any time without notice.
The Bow Bulkhead for the Wilderness Systems Tsunami 125 is designed to fit the Wilderness Systems Tsunami 125 but may need to be cut to fit.


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Grant Holman almost gave away a crucial victory with his arm, then took it back with his bat.
After being victimized for a three-run homer that put his Chula Vista, Calif., team in a hole on Wednesday night, the tall right-hander hit a three-run homer in the top of the ninth, and California rallied for a 6-3 victory over New England champion Westport, Conn., to earn a berth in the U.S. championship game at the Little League World Series.
"All I wanted to do was hit it hard," Holman said, his right arm in ice after a 10-strikeout performance and winning reliever Rennard Williams smiling at his side.
Micah Pietila-Wiggs laced a one-out single to left, his third hit of the game, to start the ninth and Jake Espinoza followed with a double to right-center before Holman connected off reliever Alex Reiner.
Chula Vista's bullpen came up big, shutting down Westport over the final five innings.
"It was fabulous," Chula Vista manager Rick Tibbett said about his relief corps. "That's what they do."
Matt Brown hit a three-run homer in the bottom of the fourth for Connecticut, and the Northeast champions seemed headed for a big victory.
But California shortstop Nick Mora hit his second homer of the game to make it 3-2 with one out in the top of the sixth and Chula Vista tied it when Reiner threw a wild pitch with the bases loaded.
The victory snapped Connecticut's 20-game winning streak.
"It's disappointing, of course, to lose," Westport manager Tim Rogers said. "It's painful to be so close to winning and lose. Obviously, they're a very talented team. There's no holes in their lineup whatsoever. We'll play tomorrow."
Westport plays Northwest champion Sammamish, Wash., on Thursday. Sammamish (3-1) moved on to the matchup in the U.S. bracket by eliminating Nashville, Tenn., 6-5 on Tuesday. Westport was coming off a 9-7 victory over Sammamish on Sunday.
Holman pitched 3 2-3 strong innings. Chasing his second no-hitter of the World Series, Holman had struck out nine - including the first six batters he faced, swinging - and was cruising when Max Popken drew a leadoff walk to start the fourth. Harry Azadian broke up Holman's no-hit bid with a single to right field and Brown then homered.
The big bats of Tijuana, Mexico, were silenced by Tokyo, Japan, in the first game Wednesday.
When Brandon Montes crushed a home run off Japan starter Kazuki Ishida, the big bats of Mexico seemed ready to rumble again.
"I definitely felt chills," Ishida said. "But I made sure to keep my composure and keep on throwing."
And hitting.
Taken out after three innings with an eye on a future game, Ishida slammed a tie-breaking home run in the bottom of the fifth inning and unbeaten Tokyo rallied past powerful Tijuana 5-2 on Wednesday to earn a berth in the international championship game at the Little League World Series.
Westport, Conn., faced powerful Chula Vista, Calif., under the lights in Wednesday's other game in the double-elimination tournament.
Ishida's blast came off Tijuana starter Ramon Mendoza. Kouyou Mizushima followed with an RBI single and pinch-hitter Kyousuke Kobayashi capped the winning rally for Japan (3-0) with an RBI double off the left-center field wall.
"I'm glad that we won. Everybody's starting to get their groove back," said Seiya Nishino, whose pinch-hit home run tied it at 2 in the fourth.
Mexico (2-1) still has a shot. It will play Aguadulce, Panama, on Thursday in a rematch. Mendoza hit two of Tijuana's five home runs in a 13-0 four-inning win over Panama on Sunday in the winners' bracket. That game was stopped because of Little League's 10-run rule, the second time Mexico had done that in the World Series.
Not on this day, though.
Ishida and winning reliever Ryutarro Takeo kept the Mexican players off-balance with a variety of off-speed pitches, never allowing the Tijuana offense to get untracked. Mexico, which also beat Perth, Australia, 12-0 in 4 innings last week, managed just five hits against Japan.
"They handle their pitchers well," Tijuana manager Francisco Fimbres said. "They paint the corners, a lot of breaking balls down low. I'll have to congratulate Japan's pitchers. The first two games we hit great. It might have been a little bit of nervousness with the importance of the game."
Mexico took a 1-0 lead in the top of the second. Axcel Mandujano reached on an error by third baseman Shunpei Takagi, who bobbled Mandujano's bouncer and threw wide of first as the Mexican player ducked under the tag.
The call stood as ruled after a challenge by Japan, and after Jorge Romero bounced into a fielder's choice, eliminating pinch-runner Luis Manzo, left-handed hitting shortstop Jorge Rodriguez doubled down the left-field line over the outstretched glove of Kobayashi to score Romero from first.
Japan evened the score in the bottom of the second. Kouyou Mizushima had a hustling double to right center and scored on a two-out single up the middle by Ryusei Hirooka.
Montes, who homered on the fifth pitch of the game in Mexico's rout of Panama, struck again in the top of the third. He slammed an 0-1 delivery well over the fence in left-center for a 2-1 lead.
Mendoza got out of a big jam in the bottom of the inning as his pitch count mounted. He walked Ishida to start the inning and Sho Miyao followed with an infield single that caromed off Mendoza's glove. That gave Japan two men on and nobody out, but first baseman Jorge Rodriguez robbed Shunpei Takagi with a beautiful stop behind the bag as the runners moved into scoring position and Mendoza induced two weak popups to escape.
Mendoza ran out of luck in the bottom of the fourth when Nishino crushed a 1-0 pitch far over the fence in center to tie it again.


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Prospect Butler sent to Double-A Tulsa
PITTSBURGH -- Rockies right-handed prospect Eddie Butler, who suffered a right rotator cuff strain during his Major League debut on June 6, was recalled from his injury rehab assignment on Saturday, then optioned to Double-A Tulsa, where he began the season.
Butler, the Rockies' No. 2 prospect as ranked by MLB.com, has had two rehab starts, one for Class A Advanced Modesto and Friday night for Triple-A Colorado Springs at Memphis -- where he gave up seven runs (six earned) and eight hits in 5 1/3 innings of a 12-1 loss.
"It's just giving him time to get sharp," Rockies manager Walt Weiss said. "He's been out for awhile. He's had a couple of rehab starts, but we're just giving him time to get everything in order, then he'll be ready to come back and help us.
"We want to make sure he's sharp and ready to go into a Major League game and succeed. He's a very young pitcher. He's only made one Major League start. We want to make sure he's in position to succeed."
Butler, a supplemental first-round Draft pick in 2013, was 4-4 with a 2.62 ERA in 11 starts at Tulsa before giving up six runs and 10 hits in 5 1/3 innings of his debut, a 7-2 loss to the Dodgers on June 6.
Weiss said he doesn't see Butler pitching at Colorado Springs -- he has yet to throw at Security Service Field, with greater altitude and more pitcher-unfriendly conditions than Denver -- as necessary before returning Butler to the Majors.
The Rockies also have a start open on Tuesday at home against the Nationals. With that pitcher more likely filling in until righty Jordan Lyles completes his rehab for a broken left hand -- Lyles is eligible to return Aug. 4 -- the starter is expected to be lefty Yohan Flande, who is on the 40-man Major League roster and is a roster-friendly move.
Thomas Harding is a reporter for MLB.com. Read his blog, Hardball in the Rockies, and follow him on Twitter @harding_at_mlb. This story was not subject to the approval of Major League Baseball or its clubs.