text:
Denver Councilman Paul Lopez picked up a thick chunk of glass from a pile of trash dumped in an alley on the city's southwest side.
Old tires, a broken sink and the frame of a television lay among weeds in a vacant lot off of South Federal Boulevard. The fence had been torched, and piles of beer bottles covered the ground.
"We have to get people to realize this neighborhood is not a dumping ground," Lopez said. "We refuse to be treated like this."
Lopez is pushing for the approval of a tougher ordinance against illegal dumping — one that could allow police to seize automobiles used in the transport of the trash and that could send violators to jail for up to a year.
The bill would add illegal dumping to the city's nuisance ordinance and will be introduced for a first vote by the Denver City Council on Monday. It's seen as a first step to corralling a problem that has been growing every year, said police Cmdr. Paul Pazen.
Last year, the city received nearly 4,500 complaints about illegal dumping, and costs for city Public Works crews to clean up the mess reached about $250,000 in 2012.
"This is something we absolutely have to get a handle on and try to help keep our city beautiful," Pazen said. "Our goal is to hold these contractors, subcontractors or scrappers who are engaging in this illegal activity accountable."
Abuse by contractors
Denver has about 17,000 roll-off trash bins that are usually located in alleyways, which have become a convenient place for construction crews to discard their waste.
Also, folks remodeling their homes or just getting rid of their junk have loaded up the bins or just thrown the waste in the alleys or vacant lots. Lopez said he has seen boats, hot tubs, refrigerators, lumber, paint and dining-room sets left out in the alleys.
"Sometimes they do it in broad daylight; sometimes they come and dump it in the dead of night," he said.
The city, which provides free trash service to all single-family homes, has a large-item pickup service every nine weeks on a rotating schedule. A maximum of five large items is collected for each household. But the illegal dumping is much different, said Mike Lutz, operations director for the city's solid-waste department.
"You do have residents who are not using the system like they should, but you also have roofing contractors or construction contractors who basically do a job, load up the back of their pickup truck and go into an alley," Lutz said. "Those are the guys we want to go after."
It has become common for people throughout the metro area to come to Denver to dump their wares, knowing the trash bins are everywhere and the penalties for an illegal-dumping violation are low.
Current penalty: $96
Pazen told City Council members about a case that occurred late at night in September when a man was seen dumping trash, including old tires, a couch and other refuse, in a Stapleton vacant lot. A resident wrote down the license plate of the pickup truck, and the suspect was questioned by police.
The suspect admitted committing the crime, saying he was a scrapper who saw a vacant lot filled with trash and figured it was OK. A trip to the landfill would have cost him $65. Instead, he got a fine of $96, Pazen said.
"Under the current system, a $96 fine wouldn't force him to do anything different," Pazen said. "We think the teeth (of this ordinance) will readily communicate that this isn't tolerated and there are consequences."
Karen Cuthbertson, president of the Athmar Park Neighborhood Association, often sees trucks with names of construction companies from neighboring jurisdictions dumping their refuse in alleyways near her home.
"They can do it for free here," she said.
"There is one gentleman who sees it so often that the police commander was considering setting up a Halo camera to catch the people," she said. "The closer you get to the city limits, the worse it is. They can come five or six blocks into Denver and dump for free and leave. I am in favor of anything that gives them more muscle to go after these guys."
Cuthbertson said she doubts many companies would risk losing one of their vehicles over illegal dumping.
"I think it would change things drastically if the person's business vehicle was taken from them," she said.
Jeremy P. Meyer: 303-954-1367, email@example.com or twitter.com/jpmeyerdpost


text:
Combative Prime Minister attacks BJP
By PTI | Published: 30th August 2013 03:14 PM |
Last Updated: 30th August 2013 07:15 PM | A+A A- |
A combative Prime Minister Manmohan Singh today made a scathing attack on the BJP in the Rajya Sabha, accusing them of hurting investors' sentiment by repeatedly disrupting Parliament, triggering a war of words.
He asked the principal opposition party to recognise its responsibility of ensuring smooth functioning of Parliament asserting that it was not the responsibility of the government alone as contended by the BJP.
"Building of consensus is both the responsibility of government and the opposition. I wish the conduct of the opposition party was consistent while letting the ruling party govern," he said responding to clarifications on his statement on the sliding Rupee.
Attacking BJP for continuously "opposing and criticising" the government, he said, "If the record of the last nine years is looked at, the principle opposition has never reconciled to the fact that it was voted out of power nine years back."
Amid repeated disruptions and din due to clashes between the Treasury Benches and the BJP, the Prime Minister noted that Parliament is the supreme body of the country but if it is not allowed to function session after session, investors' confidence will be affected.
Hurt over being targeted by BJP, Singh asked the Chair, "Have you heard of any country where the Prime Minister is not allowed to introduce his council of ministers. Have you heard of Parliament in any country where the opposition shouts 'Prime Minister chor hai'. The type of things that have been said here."
At one point, Leader of the Opposition Arun Jaitley shot back saying, "have you heard of any country where the Prime Minister has won the vote of confidence by buying MPs?", triggering uproar.
The reference was to the July 2008 Trust Vote sought by the Prime Minister in the wake of Left parties withdrawing support on the Indo-US nuclear deal issue.
Dissatisfied with Singh's statement and his replies to the clarifications, BJP members staged a walkout.
Singh earlier said it was not correct to say investors had lost confidence in India and noted that repeated disruptions of Parliament were affecting investor sentiment.
"I am not making a partisan point. If you are conscious of investment, both foreign and domestic, the conduct of Parliament is important course," he said, adding "There is a need for consensus and building a consensus is that (job) of both."
Recognising that there is a problem that needs to be resolved, he asked BJP to recognise this.
"I do recognise that there is a problem. This can be resolved only if opposition does recognise its conduct in Parliament. This is not something that can be done unilaterally. It takes two to clap," he said.
Acknowledging the need for taking corrective measures, he said, "There is a problem that foreign investors should not get wrong signals."
On corruption, the Prime Minister said, "Corruption is there, has been there. But in recent years, the RTI and the activism of various agencies has brought out certain things which are regrettable...These activisms should not be used for disruption of Parliament."
He, however, said his government has "no desire to protect the guilty" and the investigative agencies and courts were doing their job in bringing the guilty to book.
On the missing files of coal block allocation scam, Singh said, "I am not the custodian of files" that led to uproar, with BJP members questioning him "Then who is?"
"I appeal to Leader of the Opposition and all members of the House to recognise that there is a collective responsibility we owe to out country that India remains a bankable, creditable investment opportunity," he said.
The Prime Minister claimed that the fundamentals of the Indian economy were sound, but did not deny that there were deficiencies. He said there was a responsibility to act collectively to deal with the current crisis.
On inflation, he said it does hurt the poor, but various public sector agencies have helped keep prices of wheat and rice at the same level as in 2003. He said some rise in prices of foodgrains was inevitable to correct the adverse trade in agriculture and farmers needed better terms of trade.
Exuding confidence that the rising food prices would come down in view of a good harvest after a good monsoon, he said this would provide an opportunity to deal with inflation which was not possible before.
Singh refuted claims that India was moving back to the situation of 1991 financial crisis saying, "We are not at that level. We'll not go to that extent. We have no reason to believe that Indian economy is back to 1991 level...We have no reason to believe that we are going down the hill that 1991 is on the horizon," he said.
He also rubbished as "entirely unfounded" fears that Indian economy may go to 3 per cent growth level and exuded confidence that the country's economy would grow at 5.5 per cent during the current year.
"We have the resources and will power to put the economy back to high growth rate of 6 to 8 per cent," Singh claimed.
He said "FDI is not affected" and asked members not to be too much influenced by speculative inflows and outflows as "speculators are not the best judges of health of economy".
Singh said he would participate in the G-20 Summit in St Petersburg where he will raise concerns of the developing countries and ask developed nations to take into account the repercussions that their decisions have on the economy of developing countries.
"The way world economy is functioning, there is no adequate coordination of macro and fiscal policy in the world," he said.
The Prime Minister said depreciation is not a universally acceptable formula and it provides for a corrective but it has consequences on the rise in prices of petroleum products and pressure on monetary policy to take corrective measures.
He claimed that rupee depreciation provided an opportunity to put in place corrective measures by increasing exports.
Singh noted that prices of onions rise and fall and no central government can say that it can control all prices.
He said Food Minister Sharad Pawar had written to states some months back for arranging storage of onions.
"Yet no state government took advantage of that...Prices would have been more stable had states acted in time,"he said.
Earlier, Leader of Opposition Arun Jaitley attacked the government for the current state of economy and said "domestic factors have also contributed to the mess that the country has landed in".
"The legacy that you leave behind is going to be 'after we, the deluge'," he said.
While attacking the government for its failure to control economy, Jaitley said, "A failed candidate in the class always has the explanation that the whole class has failed."
Taking a jibe at Singh, he said, "We are extremely grateful to Prime Minister that he has finally spoken on the issue which is of utmost concern to the country."
He said though the country has braved many financial crises in the past, "today the situation appears to be far more gloomy".
Also read:
I am not the custodian of files in coal ministry: PM
Rupee sinking due to external factors: PM
RBI rescue effort lifts Rupee by most in 15 years, stocks jump
FM says he had said the same as Subbarao on economic woes
RBI must take steps to better forex reserves
Domestic factors also reason for crisis: PM
Govt gets it left and right, Ratan points finger at leadership deficit

subset: commoncrawl


text:
The Gauntlet Quest Is Complete And Thanos Is Here...
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Its been eight months in the making, and HeroClix players have arrived at the finale of the Infinity Gauntlet tournament series! A glove combining the power of the six Infinity Gems, the Gauntlet grants near limitless power to its wielder in the comics... and in HeroClix! Each of the first seven months of the Infinity Gauntlet series gave participating tournament players a piece of the relic (the basic Gauntlet and then one gem per month) and the chance to win an exclusive figure from the classic Infinity Gauntlet storyline. Julys Month 7 tournament completed players Gauntlets with the Mind Gem and let them play for the Grandmaster (see our review HERE). And now its time to complete the series, battling it out in month 8; August tournaments will include a Terraxia figure for participants and the grand prize Thanos!
Thanos, also known as the Mad Titan, first appeared in Marvel Comics in 1973. Obsessed with Mistress Death and seeking to impress her, the purple-skinned villain has enacted various schemes over the years. Of course, the most famous of them all has been his quest for the Infinity Gems and subsequent Gauntlet. Thanos was able to assemble the all-powerful relic and cause all sorts of havoc before ultimately being stopped and stripped of it. Thanos has appeared in HeroClix several times before, including two different versions in the recent Galactic Guardians set. But while all of those versions were powerful, this new Thanos blows them all away.
Standing 4 ¼ inches tall, this colossal Gauntlet-wielding Thanos is mounted on a 2x2 base. While overlarge, the Titan dresses the same as usual in his iconic blue and gold suit. The unique full-body outfit shows off his thick legs, barrel chest, and muscular arms. The suits hood extends over Thanos head, leaving only his purple face exposed and visible. Unique to this version of course is the Infinity Gauntlet mounted on the Titans left hand. Thanos stands in a pose right out of the comics, slightly turned to the left with his gauntleted hand raised up before him as he contemplates his newfound power and control over the universe.
Thanos is a great-looking figure with a detailed sculpt that shows off the characters blocky shape as well as his outfit. The big guy is pretty ripped with a body builders physique thats most apparent on his arms, legs, chest, and six pack. The resplendent suit has thick gloves and boots with a wrapped look, contrasting with the thin blue material. Gold outlines Thanos wide, flat belt, the trim around the bottom of his jacket, his codpiece, and his massive pointed collar. The hood follows suit with a mohawk stripe, owl-like horns over the eyebrows, and discs over the ears. Thanos purple face has tiny black beady eyes, a wide smile with gritted white teeth, and ridged chin. Finally, the Infinity Gauntlet has tiny gems mounted on it in their respective colors.
The winner of the final Infinity Gauntlet tournament doesnt just get Thanos by himself. While the figure has his own dial, theres also a massive Shrine to Death base that provides him with four more. The 5 ½ inch wide by 7 ¼ inch tall base recreates the setting of the classic series major confrontations. Steps leading up from the 3x6 base are flanked by twin visages of Death: the maiden and the skeleton. Below each face is a pile of tiny skulls, intricately carved into the architecture. The sides of the shrine are rocky walls topped by pillars and archways, themselves capped by three ever-burning fires. The centerpiece of the shrine is a sunken disc that fits a 2x2 HeroClix base, naturally Thanos. Finally, behind where the figure stands is another rocky archway that ties the whole thing together. The entire shrine is white with subtle gray-black accents that give it the look of hewn marble with the exception of the flames done in translucent orange plastic.
Following the recent trend of chase figures with different colored bases, Thanos and the Shrine are mounted on bright white dials. The Mad Titan comes with a three panel super-sized card that explains how it all works. Each dial (the one under Thanos and the four on the shrine) corresponds to a specific Issue from the Infinity Gauntlet comic series. You decide before your game which issues you want to play, then go through them in ascending order. Thanos opponent has the choice of building a team equal to the combined point total of all the issues in play OR building separate teams to play against each issue. Its a unique and fun twist on colossals with multiple point values thats going to create a ton of value and play options. Thanos dials range from 300 points (Issue 2) to 1000 points (Issue 5); play them all together for a 3000 point game. Each dial has Power Cosmic, and all but #4 (6 range, one target) have a 12 range with three targets. The incarnations of Thanos have incredible traits and special powers on top of huge stats; on top of that, all of the titles and descriptions on the card reference specific scenes and characters from the Infinity Gauntlet series further adding to its cool factor.
While previous months had the Gauntlet or its Gems as participation prizes, the finale gives each player an actual figure. Everyone gets Terraxia, a character created by Thanos during the Infinity Gauntlet series to make Mistress Death jealous. Appearing to be an idealized female version of the Mad Titan, Terraxia is a powerfully strong humanoid in her own right. The HeroClix figure captures the specific comic book panel in which the character was created with the artificial being exulting in her new existence. Terraxia leaps forward with boundless energy, her arms raised up and hair flying wild. The purple-skinned woman wears an outfit thats modeled after her creators, with some specific modifications. A blue undersuit is covered by gold cuffed boots and gloves, a tunic open at the chest, and jewelry accents around her face. Like Thanos she is powerfully muscled while still appearing feminine.
Terraxia too stands on a white base. At 100 points she has good stats and the powers of a classic brick - Charge, Flurry, Super Strength, Invulnerability, Toughness, and Close Combat Expert. She also has Indomitable to act two out of every three turns, and her first four clicks have a special power that gives Terraxia Perplex if you also control a character named Thanos. Shes a solid attacker for the points, and a great use of 100 points in high cost games with her creator on the board. Even better, the colossal Thanos can bring in Terraxia for free on Issue #3 and you can include her as one of your choices for the My Trusted Servant power on Issue #1!
Its been an intense seven months leading up to Augusts event, and players cant wait to vie for Thanos. Each prize kit has enough Terraxia participation prizes for twenty players and just one Thanos for the winner of the tournament, so competition will be fierce. All games will be played on the Shrine to Death map (included with month 7s prize kit), the very location where Thanos uses the Gauntlet. The map even has a shaded area where the colossals Shine base will fit for future games utilizing the Mad Titan. So get your team together, head on down to your local venue, and get that Thanos!
Review and Photos by Scott Rubin
Review Sample Courtesy of WizKids Games


text:
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text: I am curious if it is possible to hide threads that you just don't care about so you can get it out of the way for threads you do care about? A quick search turned up nothing, so I am assuming it is a no. Maybe it is something to look into in the future.


text:
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Income tax season is fast approaching, and students may want to consider these tips from the Kentucky Higher Education Assistance Authority (KHEAA) to help the process go more smoothly.
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text:
Saw today that Steven King wrote a book (like a fan diary) on the Red Sox during last year's season - talk about timing.
That story pales compared to the story of the Pacers this year. Someone should be following the team every day, in the locker room even.
Here's some titles to consider:
Season on the Brink 2
Last Men Standing
Hunting Season
They Have Not Yet Begun to Fight
Zeroes to Heros


text:
Sloppy Chicks (Chickpea Sloppy Joes)
1 teaspoon olive oil 1/2 red onion, diced 2-3 cloves garlic, minced ...
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I'll also be sending you weekly inspiration, motivation and more to help revolutionize your sexy self.
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text:
How to make the true Elixir of Life via the Dry and Wet Paths.
alchemy, illuminated, rosicrucian, elixir, stone, life, create, manufacture, produce, powerful, elixirs, really, work, tincutres, flasks, rosicrucis, notebook, #alchemist
Free forum : A forum meant for discussions of all sorts.
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text:
Revacept in Symptomatic Carotid Stenosis (Revacept/CS/02) (Revacept/CS/02)
This study is currently recruiting participants.
Verified June 2017 by AdvanceCor GmbH
AdvanceCor GmbH
Information provided by (Responsible Party):
AdvanceCor GmbH
ClinicalTrials.gov Identifier:
First received: July 16, 2012
Last updated: June 29, 2017
Last verified: June 2017
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Patients suffering from symptomatic carotid artery stenosis, transient ischemic attacks (TIAs), amaurosis fugax or stroke receive either Revacept (single dose) plus antiplatelet monotherapy or monotherapy alone.
Patients receive a single dose of trial medication by intravenous infusion for 20 minutes. Patients are followed up one and three days after treatment, at 3 months and by a telephone interview at 12 months.
|Carotid Stenosis Atherosclerosis Stroke Transient-ischaemic Attack TIA Amaurosis Fugax
|Drug: Revacept Drug: Placebo
|Phase 2
|Study Type:
|Study Design:
|Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
|Official Title:
|Revacept, an Inhibitor of Platelet Adhesion in Symptomatic Carotid Stenosis: A Phase II, Multicentre; Randomised, Dose-finding, Double-blind and Placebo Controlled Superiority Study With Parallel Groups
Resource links provided by NLM:
Further study details as provided by AdvanceCor GmbH:
Primary Outcome Measures:
- Assessment of incidence of microembolic signals (MES) [ Time Frame: 24 hours after treatment ]In patients with symptomatic carotid artery stenosis who have been treated with Revacept plus antiplatelet monotherapy versus antiplatelet monotherapy alone (placebo). MES will be assessed by transcranial Doppler (TCD) examination.
Secondary Outcome Measures:
- Change in rate of MES per hour [ Time Frame: 24 hours after treatment ]
- Assessment of neurological status (NIH Stroke Scale) [ Time Frame: 3 months after treatment ]
- Cerebral lesion analysis by DWI-NMR [ Time Frame: 1 day after CEA / intervention ]
- Clinical endpoint rate of all cause death [ Time Frame: up to 12 months after treatment ]
- Assessment of cardiovascular outcome [ Time Frame: 3 and 12 months ]myocardial infarction and re-intervention
- Change in vital signs [ Time Frame: up to 3 months after treatment ]
- Change in ECG parameters [ Time Frame: up to 3 months after treatment ]
- Assessment of anti-drug antibody titres [ Time Frame: up to 3 months after treatment ]
- Assessment of Adverse Events [ Time Frame: up to 3 months after treatment ]including wound healing complications, laboratory abnormalities and use of concomitant medication
- Where feasible: Assessment of Haemostasis Safety [ Time Frame: up to 3 months after treatment ]laboratory parameters indicating thrombocytopenia and bleeding according to the RE-LY study group criteria, in vitro platelet function, in vitro bleeding time by PFA-100 / PFA-200
- Clinical endpoint rate of stroke-related death [ Time Frame: up to 12 months after treatment ]
- Clinical endpoint TIA, amaurosis fugax or stroke including haemorrhagic stroke [ Time Frame: up to 12 months after treatment ]
|Estimated Enrollment:
|Study Start Date:
|March 2013
|Estimated Study Completion Date:
|December 2017
|Estimated Primary Completion Date:
|September 2017 (Final data collection date for primary outcome measure)
|Assigned Interventions
|Placebo Comparator: Phosphate buffered saline (PBS), 1% sucrose, 4% mannitol
Drug: Placebo
single intravenous injection
Active Comparator: 40 mg Revacept
in phosphate buffered saline (PBS), 1% sucrose, 4% mannitol
Drug: Revacept
single intravenous injection
Active Comparator: 120 mg Revacept
in phosphate buffered saline (PBS), 1% sucrose, 4% mannitol
Drug: Revacept
single intravenous injection
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Signed written informed consent
Target population
- Extracranial carotid artery stenosis (diagnosed by vascular duplex ultrasound peak flow or angiography)
- Lesions with ≥ 50 % stenosis according to the European Carotid Surgery Trial (ECST) criteria
- TIA, amaurosis fugax or stroke within the last 30 days
- Age and sex: Men and women aged > 18 years Women of childbearing potential (WOCBP) must be using an adequate method of contraception to avoid pregnancy throughout the study and for up to 4 weeks after receiving investigational product in such a manner that the risk of pregnancy is minimised.
Exclusion Criteria:
Sex and reproductive Status:
- WOCBP who are unwilling or unable to use an acceptable method to avoid pregnancy for up to 4 weeks after receiving investigational product.
- Women who are pregnant or breastfeeding
- Women with a positive pregnancy test on enrollment or prior to investigational product administration.
Target disease exceptions
- NIHSS score > 18
- Recent intracerebral haemorrhage by X-ray computed tomography (CT) or nuclear magnetic resonance (NMR)
- Cardiac cause of embolisation (atrial fibrillation or other cardiac source e.g. artificial heart valves)
Medical history and concurrent disease
- History of hypersensitivity, contraindication or serious adverse reaction to inhibitors of platelet aggregation, hypersensitivity to related drugs (cross-allergy) or to any of the excipients in the study drug
- History or evidence of thrombocytopenia (<30.000/ul), bleeding diathesis or coagulopathy (pathological international normalised ratio (INR) or activated partial thromboplastin time (aPTT))
- Thrombolysis within the last 48 hours
- Relevant haemorrhagic transformation as determined by CT, NMR or anamnesis
- Oral anticoagulation or dual anti-platelet therapy with aspirin or clopidogrel and other P2Y inhibitors at screening (3 days for dipyridamole extended release; 8 hours for tirofiban/Aggrastat)
- Sustained hypertension (systolic BP > 179 mmHg or diastolic BP >109 mmHg)
- History of severe systemic disease such as terminal carcinoma, renal failure (or current creatinine > 200 umol/l), cirrhosis, severe dementia, or psychosis
- Current severe liver dysfunction (transaminase level greater than 5-fold over upper normal range limit)
- Active autoimmune disorder such as systemic lupus erythematosus, rheumatoid arthritis, vasculitis or glomerulonephritis
- Known atrial fibrillation or other clinically significant ECG abnormalities (at present)
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01645306
Please refer to this study by its ClinicalTrials.gov identifier: NCT01645306
|Contact: Holger Poppert, PD Dr. med.
|004989-4140 ext 4606
|Site 01: Department of Neurology, TU Munich
|Munich, Bavaria, Germany, 81675
|Contact: Holger Poppert, PD Dr. med. +49 89 4140 ext 4606
|Principal Investigator: Holger Poppert, PD Dr. med.
|Site 08: Universitätsklinikum Essen, Klinik für Neurologie
|Essen, Germany, 45147
|Contact: Melanie Dietzold
|Principal Investigator: Christian Weimar, Prof. Dr. med.
|Site 11: Universitätsklinikum Hamburg Eppendorf
|Hamburg, Germany, 20246
|Contact: Dagmar Otto
|Contact: Kirsten Jaramillo
|Principal Investigator: Götz Thomalla, PD Dr. med.
|Principal Investigator: Amir Golsari, Dr. med.
|Site 07: Medizinische Hochschule Hannover, Klinik für Neurologie
|Hannover, Germany, 30625
|Contact: Hans Worthmann, Dr. med. +49 511 532 ext 3580
|Principal Investigator: Karin Weißenborn, Prof. Dr. med.
|Principal Investigator: Hans Worthmann, Dr. med.
|Site 12: Universitätsklinikum Leipzig AöR
|Not yet recruiting
|Leipzig, Germany, 04103
|Contact: Daniela Urban
|Contact: Rita Lachmund
|Principal Investigator: Dominik Michalski, PD Dr. med.
|Site 09: Universitätsmedizin Mainz, Klinik und Poliklinik für Neurologie
|Mainz, Germany, 55131
|Contact: Klaus Gröschel, PD Dr. med.
|Principal Investigator: Klaus Gröschel, PD Dr. med.
|Sub-Investigator: Timo Uphaus
|Site 04: Universitätsklinikum Tübingen, Klinik für Allgemeine Neurologie
|Tübingen, Germany, 72076
|Contact: Sven Poli, Dr. med. 07071 29 ext 84427
|Contact: Julia Zeller
|Principal Investigator: Sven Poli, Dr. med.
|Principal Investigator: Ziemann Ulf, Prof. Dr. med.
|Site 06: Universitätsklinikum Ulm, Abteilung für Neurologie
|Ulm, Germany, 89081
|Contact: Sabine Raubold +49 731 177 ext 5721
|Principal Investigator: Hermann Neugebauer, Dr. med.
|Principal Investigator: Katharina Knauer, Dr. med.
|United Kingdom
|Site 23 - University Hospital Coventry NHS Trust
|Coventry, United Kingdom, CV2 2DX
|Contact: Chris Imray, MD
|Principal Investigator: Chris Imray, MD
|Site 26 - University College London Hospital
|London, United Kingdom, NW1 2BU
|Contact: Toby Richards, MD
|Principal Investigator: Toby Richards, MD
|Site 28 - King's College London Hospital
|London, United Kingdom, SE5 8AF
|Contact: Hisham Rashid
|Principal Investigator: Hisham Rashid
|Site 20: St George's NHS Trust
|London, United Kingdom, SW17 0QT
|Principal Investigator: Ian M Loftus, MD
Sponsors and Collaborators
AdvanceCor GmbH
|Principal Investigator:
|Holger Poppert, PD Dr. med.
|Department of Neurology, TU Munich
|Principal Investigator:
|Ian M Loftus, MD
|St George's NHS Trust
More Information
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on September 21, 2017
Bültmann A, Li Z, Wagner S, Peluso M, Schönberger T, Weis C, Konrad I, Stellos K, Massberg S, Nieswandt B, Gawaz M, Ungerer M, Münch G. Impact of glycoprotein VI and platelet adhesion on atherosclerosis--a possible role of fibronectin. J Mol Cell Cardiol. 2010 Sep;49(3):532-42. doi: 10.1016/j.yjmcc.2010.04.009. Epub 2010 Apr 27.
Goertler M, Baeumer M, Kross R, Blaser T, Lutze G, Jost S, Wallesch CW. Rapid decline of cerebral microemboli of arterial origin after intravenous acetylsalicylic acid. Stroke. 1999 Jan;30(1):66-9.
Markus HS, Droste DW, Kaps M, Larrue V, Lees KR, Siebler M, Ringelstein EB. Dual antiplatelet therapy with clopidogrel and aspirin in symptomatic carotid stenosis evaluated using doppler embolic signal detection: the Clopidogrel and Aspirin for Reduction of Emboli in Symptomatic Carotid Stenosis (CARESS) trial. Circulation. 2005 May 3;111(17):2233-40. Epub 2005 Apr 25.
Massberg S, Konrad I, Bültmann A, Schulz C, Münch G, Peluso M, Lorenz M, Schneider S, Besta F, Müller I, Hu B, Langer H, Kremmer E, Rudelius M, Heinzmann U, Ungerer M, Gawaz M. Soluble glycoprotein VI dimer inhibits platelet adhesion and aggregation to the injured vessel wall in vivo. FASEB J. 2004 Feb;18(2):397-9. Epub 2003 Dec 4.
Molloy J, Markus HS. Asymptomatic embolization predicts stroke and TIA risk in patients with carotid artery stenosis. Stroke. 1999 Jul;30(7):1440-3.
Nieswandt B, Watson SP. Platelet-collagen interaction: is GPVI the central receptor? Blood. 2003 Jul 15;102(2):449-61. Epub 2003 Mar 20. Review.
Ringelstein EB, Droste DW, Babikian VL, Evans DH, Grosset DG, Kaps M, Markus HS, Russell D, Siebler M. Consensus on microembolus detection by TCD. International Consensus Group on Microembolus Detection. Stroke. 1998 Mar;29(3):725-9.
Schönberger T, Siegel-Axel D, Bussl R, Richter S, Judenhofer MS, Haubner R, Reischl G, Klingel K, Münch G, Seizer P, Pichler BJ, Gawaz M. The immunoadhesin glycoprotein VI-Fc regulates arterial remodelling after mechanical injury in ApoE-/- mice. Cardiovasc Res. 2008 Oct 1;80(1):131-7. doi: 10.1093/cvr/cvn169. Epub 2008 Jun 19.
Ungerer M, Rosport K, Bültmann A, Piechatzek R, Uhland K, Schlieper P, Gawaz M, Münch G. Novel antiplatelet drug revacept (Dimeric Glycoprotein VI-Fc) specifically and efficiently inhibited collagen-induced platelet aggregation without affecting general hemostasis in humans. Circulation. 2011 May 3;123(17):1891-9. doi: 10.1161/CIRCULATIONAHA.110.980623. Epub 2011 Apr 18.
Jamasbi J, Megens RT, Bianchini M, Münch G, Ungerer M, Faussner A, Sherman S, Walker A, Goyal P, Jung S, Brandl R, Weber C, Lorenz R, Farndale R, Elia N, Siess W. Differential Inhibition of Human Atherosclerotic Plaque-Induced Platelet Activation by Dimeric GPVI-Fc and Anti-GPVI Antibodies: Functional and Imaging Studies. J Am Coll Cardiol. 2015 Jun 9;65(22):2404-15. doi: 10.1016/j.jacc.2015.03.573.
|Responsible Party:
|AdvanceCor GmbH
|ClinicalTrials.gov Identifier:
|NCT01645306 History of Changes
|Other Study ID Numbers:
|Study First Received:
|July 16, 2012
|Last Updated:
|June 29, 2017
Additional relevant MeSH terms:
Constriction, Pathologic
Ischemic Attack, Transient
Carotid Stenosis
Amaurosis Fugax
Pathological Conditions, Anatomical
Arterial Occlusive Diseases
Vascular Diseases
Cardiovascular Diseases
Brain Ischemia
Cerebrovascular Disorders
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Carotid Artery Diseases
Vision Disorders
Sensation Disorders
Neurologic Manifestations
Eye Diseases
Signs and Symptoms
Diuretics, Osmotic
Natriuretic Agents
Physiological Effects of Drugs
ClinicalTrials.gov processed this record on September 21, 2017


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STARmeterSEE RANK
Up 4,475 this week
Buzz Aldrin
Buzz Aldrin was born on January 20, 1930 in Montclair, New Jersey, USA as Edwin Eugene Aldrin Jr. He is known for his work on The Other Side of the Moon (1990), Fly Me to the Moon 3D (2008) and Passage to Mars (2016). He was previously married to Lois Driggs Cannon, Beverly Van Zile and Joan Ann Archer. See full bio »
Born:in Montclair, New Jersey, USA
More at IMDbPro » Contact Info: View agent, manager and publicist


text: Can alcohol sales and an expanded array of food choices provide the boost White Castle is seeking? QSR chain White Castle, a 90-year-old hamburger chain that sells square "slider" burgers, has begun serving beer and wine in an Indiana location as part of a test program, the Chicago Tribune reported. And White Castle is not


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Go Shopping: Acquiring Companies Beating S&P 500, Strategas Says
Companies aren't spending yet, but they are going shopping--and investors are rewarding them for it, according to Strategas Research Partners.
Since the start of the year, companies making acquisitions have outperformed the S&P 500 by more than two percentage points from the day the takeover is announced, according to Strategas' Jason DeSena Trennert and team. They write:
In a world of 2-3% real GDP growth, already-high margins, and very optimistic expectations for earnings in 2014 (the bottom up consensus is $122.94), it appears as if we were reaching the point at which something's got to give. Share buybacks and dividend increases are nice but what really seems to be lacking is a commitment to top line growth. While it appears that companies have not yet been rewarded for increased capital expenditures, the market is giving extra credit to those companies seeking growth through acquisition.
Some of the best-performing acquirers include Berkshire Hathaway (BRK.A), which has gained 17% since its acquisition of H.J. Heinz on Feb. 14, Comcast (CMCSA), which has risen 14% since announcing the take over NBC Universal on Feb. 12, Thermo Fisher (TMO), which has advanced 19% since announcing it would buy Life Technologies on April 15, and Kroger (KR), which is up 9.7% since saying it would buy Harris Teeter Supermarkets on July 9.


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NEW YORK Barnes & Noble has announced that its new "Barnes & Noble Classics" promotion will give customers the opportunity to enjoy classic literature for free on a variety of platforms, including NOOK e-book readers, iPad, PC and other mobile and computing devices using BN e-reader software.
"With this exciting offer of dozens of free, high-quality Barnes & Noble classics e-book titles beginning today and in the coming weeks, we're continuing to give our customers new ways to experience and enjoy e-reading," said Sasha Norkin, VP acquisition marketing for Barnes & Noble.com. "We believe our customers will appreciate the ability to add many of our Barnes & Noble Classics to their growing personal digital libraries at no cost, and those new to e-reading can try out one of their childhood favorites on the mobile or computing device of their choice, using our free BN e-reader software."


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Nuclear Power and Proliferation Resistance
Securing Benefits, Limiting Risks
Global electricity demand is expected to increase by more than 50 percent by 2025 and nuclear power is a primary carbon-free energy source for meeting this extensive global energy expansion. At the same time, the technologies used in peaceful nuclear power programs overlap with those used in the production of fissionable material for nuclear weapons. This report examines technological steps that the US can take to enhance the proliferation resistance of nuclear power systems.


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Shopping for the Best Air Mattress
For about 5 years in my life, I had to do a lot of moving and even a bit of travel. The longest I've stayed in one residence was for 1.5 years. I lived in small houses, homeowner's attics, apartments, and cramped studio rooms. While traveling, I chose the smallest room possible, most of them with uncomfortable (or questionable) beds. While space may have been tight, one thing I never suffered from was a good night's rest.
The stress of constantly moving, going to college, working, and the occasional travel can take a toll on someone's well-being. Thankfully, I don't look back at those days as being a horrible, stressful time, and I attribute most of that to having restful sleep every night, thanks to my handy air mattress.
My air mattress lasted me many years. I took it with me everywhere, and saved a ton of money by not having to rent trucks to move a huge traditional mattress, as well as being able to stay in smaller apartments due to not needing so much space. Even if no one place was ever "home" for me, my air mattress helped bring that feeling of security and stability since that never changed, regardless of my surroundings.
Possessions, relationships and jobs came and went. However, my investment in a quality air mattress was easily the best decision I ever made. Even today, I keep an extra one on hand for those nights where we have overnight guests, or certain days where I need extra firmness my traditional bed can't cover.
The air mattress you choose today has to satisfy strict requirements. After all, this is your health and quality of sleep on the line! The ability to easily inflate and deflate to adjust to your desired firmness at any time is crucial. Without enough spine support, you can wake up with aches and pains, and it can negatively affect your sleep quality.
A convenient travel bag makes it simple to deflate, fold up and go in a matter of minutes. Time is of the essence for all of us, and shaving off minutes to pack up and go is no longer a luxury, but a necessity. A good travel bag is waterproof, sturdy, easy to carry and fits in any suitcase or duffel bag.
Depending on your usage and lifestyle, the initial investment in a quality air mattress will pay for itself in as little as a few weeks. It's great for singles, those living frugally, travelers constantly on the go, backpackers, and students.
SimplySleeper air mattresses and air beds are the perfect companion for any of the above, and are great to have around the house for anyone else. Have lots of overnight guests? Move a few furniture and inflate a comfortable SimplySleeper for a sound night's rest. Staying at a motel overnight for a business trip, but prefer not to sleep in a previously occupied bed? Use a lightweight SimplySleeper air mattress, adjusted just for your desired firmness and comfort.
SimplySleeper air mattresses are simply the best in the industry. With such benefits as the below, you'll wonder why you ever went without:
Available in a wide variety of sizes and all constructed with heavy-duty polyester Durmothane technology for the ultimate in breathable fabric and comfort that adjusts to your body temperature.
You can turn any room into a cozy chamber of slumber quickly and economically with a quality SimplySleeper air mattress. They will meet and exceed your expectations for the quality of sleep you deserve, even from a convenient air mattress.
When you're out shopping for portable audio speakers, it's hard to know which one has the best quality AND won't put a hole in your wallet. There are so many brands, models, and features that could easily overwhelm anyone shopping for new speakers. However, once you try out the SimplyVibe V5-BT1, you'll never have trouble shopping for speakers again.
The SimplyVibe V5-BT1 portable speakers are the newest model that have been introduced on SimplyGlobo's website. One of the best features of this product is that it is Bluetooth which means it can hook up to your laptops, smartphones or tablets without dealing with any cords or plugging anything in. It's very simple to pair your device with the speakers and the instructions are user friendly and straightforward. Once your device is paired up, all you have to do is choose a song and hit play! You can control the volume as well as switch songs from either your own device or the speakers which I find very convenient. These amazing speakers can play up to 18 hours on medium volume without needing a charge, so you don't have to worry about charging it all of the time. The speakers aren't the only thing that can be charged; in case your phone battery is about to die, you can use the included USB and charge your phone using the speakers. That's a very special feature that you won't find on a lot of portable speakers. Also, if you're using your smartphone to listen to music and you get a call at the same time, you can answer the call using the product as a speakerphone! It takes one press of the button and you can talk to someone straight from the speaker and then go right back to listening to your music. After learning about all of the unique features of the SimplyVibe V5-BT1, I hope this helps make your shopping experience a lot less stressful! Happy shopping!


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Instructions for authors
BMC Hematology is an open access, peer-reviewed journal that considers articles on basic, experimental and clinical research related to hematology. The journal welcomes submissions on non-malignant and malignant hematological diseases, hemostasis and thrombosis, hematopoiesis, stem cells and transplantation.
BMC Hematology is part of the BMC series which publishes subject-specific journals focused on the needs of individual research communities across all areas of biology and medicine. We offer an efficient, fair and friendly peer review service, and are committed to publishing all sound science, provided that there is some advance in knowledge presented by the work.
BMC series - open, inclusive and trusted.
Each article type published by BMC Hematology follows a specific format, as detailed in the corresponding instructions for authors; please choose an article type from the list on the left to view the instructions for authors.
The instructions for authors includes information about preparing a manuscript for submission to BMC Hematology, criteria for publication and the online submission process. Other relevant information about the journal's policies, the refereeing process and so on can be found in 'About this journal'.
BMC Hematology publishes the following article types:
- Research articles
- Case reports
- Database articles
- Debates
- Software articles
- Study protocols
- Technical advance articles
We use plagiarism detection
This journal is a member of, and subscribes to the principles of, the Committee on Publication Ethics (COPE).
Authors and referees are asked to declare any competing interests.
Copyright rests with the authors. For more information on copyright of articles, see our publisher's copyright and license policy.


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SHEPHERDSVILLE - The Bullitt Central Lady Cougars were flying high coming off a championship in their second holiday tournament, the Lady Wolverine Classic in Frankfort, but since returning home, life has become complicated for coach Bryan Bates' team.
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NetWellness is a global, community service providing quality, unbiased health information from our partner university faculty. NetWellness is commercial-free and does not accept advertising.
Sunday, September 24, 2017
Skin Care and Diseases
Why does Sunscreen Tan my Skin?
I am African-American. When I use sunscreen daily, my skin becomes a deeper, darker, beautiful, dark brown. My skin does not tan as much when I am in the sun without sunscreen. Why does sunscreen affect my skin in this way?
Sunscreens are formulated to filter the ultraviolet wavelengths (290 to 400 nm) emitted by the sun. There are portions of the UV spectrum that are better filtered than others. For example, only a few sunscreen filters can absorb long wavelength UVA, and still not perfectly, as wavelengths beyond 370 nm are not completely filtered. So there could still be some UV rays that are penetrating and able to modify the character of the skin, even with sunscreen on. For example, the type of brown pigmentation you are noticing may be brought about by longer UVA wavelengths or even visible light from the sun, which also has some biologic effects. Without sunscreen, you're relying on your inherent pigmentation to filter UV, and so the natural tanning response may be different than when you have sunscreen on.
Elma D Baron, MD
Associate Professor of Dermatology
Director, Skin Study Center
School of Medicine
Case Western Reserve University


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Genus: Caretta
Species: caretta
Loggerheads were named for their relatively large heads, which support powerful jaws and enable them to feed on hard-shelled prey, such as whelks and conch. The most common sea turtle in U. S. coastal waters. the loggerhead sea turtle was listed as threatened throughout its range on July 28, 1978, under the Endangered Species Act of 1973, and has received Federal protection since that time.
Description: The adult loggerhead has a slightly heart-shaped, reddish-brown carapace (top shell of a turtle) consisting of five or more pleural scutes and a yellow plastron (bottom shell of a turtle). Adult males are distinguished by long tails that extend beyond the rear carapace in addition to a narrowing of the carapace that tapers towards the rear.
Hatchlings have light to dark gray/brown shells. Their flippers are dark brown with white edges and their belly is a faded yellow.
Diet: Loggerheads are carnivores, subsisting on crustaceans, fish, and other marine animals. The hatchlings feed on small animals living in the sea grass-like algal mats called sargassum, where they spend their early developmental years. Juveniles and adults eat mostly bottom dwelling invertebrates such as whelks, other mollusks, horseshoe crabs, and sea urchins. Their powerful jaws are designed to crush their prey.
Size: Loggerheads in the southeastern U.S. weigh an average of 250 lbs (113 kg) and are generally about 36 inches (92 cm) long.
Habitat: Loggerheads can be found hundreds of miles out to sea or in inshore waters — bays, lagoons, salt marshes, creeks, ship channels, and the mouths of large rivers. Coral reefs, rocky places, and ship wrecks draw large amounts of marine life and are great feeding areas.
Loggerheads nest on ocean beaches and occasionally on estuarine (where a river meets the sea) shorelines with suitable sand. Nests are typically made between the high tide line and the dune front.
Most loggerhead hatchlings originating from U.S. beaches are believed to lead a pelagic (open sea) existence in the North Atlantic for an extended period of time, perhaps as long as 10 to 12 years, and are best known from the eastern Atlantic near the Azores and Madeira.
As mentioned previously, post-hatchlings take cover in floating mats of sargassum, but once they reach a certain size, these juvenile loggerheads begin "recruiting" to coastal areas in the western Atlantic where they become "benthic" feeders in lagoons, estuaries, bays, river mouths, and shallow coastal waters. These juveniles occupy coastal feeding grounds for a decade or more before maturing and making their first reproductive migration.
Typical Lifespan: Scientists believe that loggerheads are long lived and could live to 50 years or more.
Range: The loggerhead sea turtle is a wide-ranging species, occuring throughout the temperate sub-tropical and tropical regions of the Atlantic, Pacific, and Indian Oceans. In the Atlantic, the loggerhead turtle's range extends from Newfoundland to as far south as Argentina.
In the eastern Pacific, loggerheads have been reported as far north as Alaska, and as far south as Chile. In the U.S., occasional sightings are reported from the coasts of Washington and Oregon, but most records are of juveniles off the coast of California. The west coast of Mexico, including the Baja Peninsula, provides critically important developmental habitats for juvenile loggerheads. The only known nesting areas for loggerheads in the North Pacific are found in southern Japan.
Adult loggerheads are known to make extensive migrations between foraging areas and nesting beaches. During non-nesting years, adult females from U.S. beaches are distributed in waters off the eastern U.S. and throughout the Gulf of Mexico, Bahamas, Greater Antilles, and Yucatán.
Life History and Reproduction: Female loggerheads reach maturity at about 35 years of age. Every 2-3 years, they mate in coastal waters and then return to nest on the very same beach where they were hatched, called the "natal" beach. The nesting season begins in April and ends in September, with the peak in June. They emerge onto the beach at night every 14 days, laying an average of 4 clutches containing roughly 100 – 120 eggs in each. Sex of hatchlings is determined by incubation temperature. Warmer temperatures result in the great majority being females and cooler temperatures produce mainly or only males.
The majority of loggerhead nesting occurs in the western rims of the Atlantic and Indian Oceans, primarily in Oman, the United States, and Australia. The greatest nesting concentrations in the U.S. occur on beaches from North Carolina through southwest Florida, and minimal nesting extends westward to Texas and northward to southern Virginia.
Of the loggerhead nesting activity within the southeastern U.S., about 80% occurs in six Florida counties (Brevard, Indian River, St. Lucie, Martin, Palm Beach, and Broward Counties). In Brevard and Indian River Counties, a 20 mile section of coastline from Melbourne Beach to Wabasso Beach comprises the Archie Carr National Wildlife Refuge (ACNWR), which is the most important loggerhead nesting area in the western hemisphere. Nesting densities of 1,000 nests per mile (625 nests per km) are recorded for beaches within the ACNWR.
Threats: Loggerhead turtles have long been hunted for their eggs and for leather. Other threats include:
Conservation Efforts:
Loggerhead sea turtles are protected by various international treaties and agreements as well as national laws such as the U.S. Endangered Species Act (ESA).
In 2008 NOAA's National Marine Fisheries Service (NMFS) and the U.S. Fish & Wildlife Service (USFWS) updated the recovery plan for the loggerhead turtle.
Bycatch of loggerhead turtles (accidental capture by commercial and sport fishermen) is being reduced by fishing gear modifications (i.e. use of TED's or turtle exclusion devises), changes to fishing practices and closures of certain areas to fishing during nesting and hatching seasons.
Many coastal counties and communities in Florida, Georgia, and South Carolina have developed lighting ordinances to reduce hatchling disorientations.
Important U.S. nesting beaches have been and continue to be acquired for long-term protection.
Regular monitoring of loggerhead turtle populations by NMFS and USFWS, and further research on the biology, life cycle, and migration patterns is needed to help develop effective conservation methods.
US Fish & Wildlife Service
NOAA Fisheries Office of Protected Resources
Mamanuca Environment Society
NatureServe Explorer
Sea turtles nesting in the southeastern United States are recovering, but the ancient reptiles still face formidable threats
A program that enlists the help of local volunteers is reversing the leatherback sea turtle decline in the Caribbean and serving as a model for other areas


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Alvarez's return puts crowded rotation in flux
Marlins not planning on going with six-man staff; off-days next week a factor
MIAMI -- The Marlins are set to reinstate Henderson Alvarez from the disabled list on Saturday to face the D-backs. After that, the rotation is in a state of flux.
With scheduled days off on Monday and Thursday (Aug. 21) next week, manager Mike Redmond and pitching coach Chuck Hernandez are in the process of adjusting the rotation.
For now, all that is set is Brad Penny will start the series opener with Arizona on Thursday, followed by Brad Hand on Friday and Alvarez on Saturday.
Jarred Cosart could fall in line to start Sunday in the finale of the four-game series with the D-backs. But he has not officially been announced.
Once Alvarez comes off the DL, the team will have to make a decision, because it isn't planning on going with six starters.
Alvarez, on the DL retroactive to July 30 with right shoulder inflammation, threw a bullpen session on Wednesday.
"We've talked about getting guys an extra day, and I think it sort of sets up that way, where we can get each guy one extra day," Redmond said.
Joe Frisaro is a reporter for MLB.com. He writes a blog, called The Fish Pond. Follow him on Twitter


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Endobronchial Valve for Emphysema PalliatioN Trial (VENT) Cost-effectiveness Sub-Study
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
|Emphysema Chronic Obstructive Pulmonary Disease
|Device: Emphasys Endobronchial Valve (EBV) Device and Procedure
|Phase 3
|Study Type:
|Study Design:
|Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
|Official Title:
|Endobronchial Valve for Emphysema PalliatioN Trial (VENT) Cost-effectiveness Sub-Study
- The cost-effectiveness ratio in the treatment group as compared to the control group at 180 days
- The cost-effectiveness ratio in the treatment group of the study will be compared to established therapies and standards.
|Estimated Enrollment:
|Study Start Date:
|December 2004
Therapeutic interventions in health care require the use of resources. Since these resources are limited, it is important for clinical decision-makers to have economic information in addition to safety and efficacy data. In the economic environment of health care today, the incremental costs for a new therapeutic intervention must be offset by the value associated with better outcomes such as improved health and health-related quality of life and/or lower health care utilization costs over time.
Questions about the cost and effectiveness of medical care have generated considerable attention in medical outcomes research. In 1993, the Department of Health and Human Services appointed a multi-disciplinary group to recommend standards for the evaluation of health care. The panel's report suggested that standardized outcomes analyses be conducted to evaluate the cost-effectiveness of medical care. These analyses require preference-weighted measures of health-related quality of life. Such measures are needed in order to adjust survival time for health-related quality of life.
|Ages Eligible for Study:
|40 Years to 75 Years (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Diagnosed by high-resolution computed tomography (HRCT) with eligible heterogeneous disease distribution
- Forced expiratory volume in 1 second (FEV1) < 45% predicted
- Total lung capacity (TLC) > 100% predicted
- Residual volume (RV) > 150% predicted
- Post rehabilitation 6 minute walk test > 140m
- Non-smoking for 4 months
Exclusion Criteria:
- Prior lung transplant, lung volume reduction surgery (LVRS), median sternotomy, bullectomy or lobectomy
- History of recurrent respiratory infections
- Evidence of large bullae (> 30% of either lung) in a non-target lobe
- FEV1 < 15% predicted
- Diffusing capacity of the lung for carbon monoxide (DLCO) < 20% predicted
Please refer to this study by its ClinicalTrials.gov identifier: NCT00137956
|Principal Investigator:
|Robert Kaplan, PhD
|UCLA School of Public Health, UCSD Health Outcomes Assessment Program (HOAP)
|ClinicalTrials.gov Identifier:
|NCT00137956 History of Changes
|Other Study ID Numbers:
|Study First Received:
|August 26, 2005
|Last Updated:
|August 14, 2009
Keywords provided by Emphasys Medical:
Endobronchial Valve
Endobronchial Valve ProcedureEBV
EBV Procedure
Endobronchial Lung Volume Reduction
Lung Volume Reduction
Additional relevant MeSH terms:
Lung Diseases
Lung Diseases, Obstructive
Pulmonary Disease, Chronic Obstructive
Pulmonary Emphysema
Respiratory Tract Diseases
Pathologic Processes
ClinicalTrials.gov processed this record on September 19, 2017


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This commentary also appears on Real Money Pro -- Click here to learn about this dynamic market information service for active traders.
I feel like part of the crowd doesn't trust this rally, which means it probably isn't done. It won't make me a chaser, but I don't feel like the market is going to completely fall apart this week. It does give me the courage to take some overnight shots into a few names or some earnings plays.
I like the risk-reward on Urban Outfitters' (URBN) chart. Has the same-stores sales trough finally passed? A few other retailers have posted surprisingly strong numbers and if URBN were to surprise to the upside, this chart is poised to push the stock into the low $40s quickly. I'm going to approach this in a slightly different fashion, though from a trading standpoint just in case URBN disappoints. I am buying the December $36 calls while shorting the January $37-$42 call spreads with a target of $1 or less. I'll try for these at $0.95, but given I've traded URBN options many times in the past, the bid-ask spread is a tougher one to crack, so while I believe $1 can likely be filled, $0.95 will require some more patience.
Another one I am watching (a hat tip to @lancelotw on Twitter for tossing this chart to me last week for discussion and digestion) is O'Reilly Automotive (ORLY), which is kind of breaking out today. At first, I thought any move over $90 would send this off to the races, but upon closer inspection, a move over $90 only sets the stock up for a move to $92, where the key to $100 is held. The $92 price looks like the bigger resistance in this channel/flag. Above $92 and I want to be long ORLY with a stop just below the 200-day moving average. A shorter-term trend, the 13-day simple moving average, may be a better place to position the stop as this will act as more of a trailing stop rather than a positional stop. The stochastics are already breaking out higher with RSI pushing resistance as well. If these two break out higher, then the setup is in place to get long this stop aggressively for a trade on a move over $92 with a stop in place.


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Contractor Wet/Dry 16 Gallon Vac
Durable, quiet and economical cleanup of messes big and small
Contractor Wet/Dry 16 Gallon Vac is perfect for use in your shop or classroom, yet tough enough to handle construction site cleanup. Single-stage bypass motor runs quietly. Poly tank with top handle and two-latch lid is easy to empty. On/off switch is easily accessible. Lock-On ® positive connection hose system, high-quality cartridge filter and foam sleeve. Onboard tool storage and convertible blower port. Includes two-piece
extension wand, floor nozzle, crevice tool and casters. 16-gal. model has a 18-ft. long power cord. Includes a high-efficiency collection bag filter. Hose dimensions (Dia. x L) 2-1/2" x 8ft. Replacement cartridge filter
(sold separately). USA made.


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Fairfax County Presents: Free Seminars for Family Caregivers from March through May
February 19, 2010
Fairfax County's Free Seminars for Family Caregivers series offers 11 events this spring to help family caregivers of older adults and adults with disabilities throughout the county. Speakers include experts in law, insurance, care management, finances and community resources.
New this spring is a seminar on supporting caregivers of veterans scheduled for March 25.
People are welcome to attend one or all of the seminars.
For more information, to register, or to request reasonable accommodations go to www.fairfaxcounty.gov/dfs/olderadultservices and link to Events, e-mail email@example.com or call 703-324-5205, TTY 703-449-1186.
Understanding Medicare, Medigap and Medicare Part
Learn the facts about health insurance for older adults.
Tuesday, March 16, 7-9:00 p.m.
West Springfield Government Center
6140 Rolling Road
Springfield, VA 22152
Caregiving 101
Learn about resources and get useful information to help you begin the caregiver journey.
Tuesday, March 23, 7-9:00 p.m.
Hollin Hall Senior Center
1500 Shenandoah Road
Alexandria, VA 22308
Supporting Caregivers of Veterans
Find information on resources available to veterans and their caregivers.
Thursday, March 25, 7-9:00 p.m.
Hollin Hall Senior Center
1500 Shenandoah Road Alexandria, VA 22308
Directions: 703-765-4573
Making Life Easier: Gadgets, Gizmos and Home
Learn about home modifications and inexpensive devices that can help your loved one maintain independence.
Wednesday April 7, 1-3:00 p.m.
Oakton Library
10304 Lynnhaven Place
Oakton, VA 22124
Navigating the Medicaid Maze: Waivers, Eligibility and
The costs of long-term care can quickly drain even a substantial savings account. Learn about Medicaid's eligibility criteria, screening process, required documentation, and Medicaid's home-based and nursing home care.
Thursday, April 8, 7 - 9:00 p.m.
West Springfield Government Center
6140 Rolling Road
Springfield, VA 22152
Directions: 703-451-8873
Legal Tools for Caregivers
Family caregiver may need to make legal and health care decisions for a loved one. Learn about legal tools that can help ensure your loved one's wishes are carried out. Topics include durable power of attorney, trusts, guardianship, and advanced medical directives.
Tuesday, April 20, 7-9:00 p.m.
Mason Governmental Center
6507 Columbia Pike
Annandale, VA 22003
Stages of Alzheimer's Disease
While each individual's journey with Alzheimer's disease is unique, there are common markers along the way. Learn what to expect as the disease progresses and how to adapt to the changing needs of your loved one and family.
Thursday, April 29, 1-3:00 p.m.
Alzheimer's Family Day Center
2812 Old Lee Highway
Fairfax, VA 22031
Financial Issues for Caregivers
Professional long-term care is expensive and can deplete assets quickly. Get in-depth information on how to maximize your resources, stretch financial assets and avoid common money mistakes that caregivers make.
Thursday, April 29, 7-9:00 p.m.
Mason Governmental Center
6507 Columbia Pike
Annandale, VA 22003
Behavior as Communication in Alzheimer's Disease
People with Alzheimer's disease often communicate through behavior. It is sometimes difficult for caregivers to understand this communication. Learn how to improve communication with a person who has Alzheimer's disease and how to anticipate and minimize troubling behaviors.
Wednesday, May 5, 7 - 9:00 p.m.
Herndon Senior Center
873 Grace Street
Herndon, VA 20171
When Do I Step In?
Deciding when and how to help an older adult can be a difficult decision. Common concerns include driving, safety, health, and finances. Learn how and when to step in and how to find help assigning financial and medical oversight to a more competent relative at the appropriate time.
Thursday, May 6, 7-9:00 p.m.
Sully Governmental Center
4900 Stonecroft Blvd.
Chantilly, VA 20151
Managing Care for a Difficult Older Adult
Helping a loved one can involve challenging personalities and behaviors as well as relationship issues. Learn strategies to deal with these factors as you provide the best care possible.
Wednesday, May 12, 7-9:00 p.m.
Little River Glen Senior Center
4001Barker Court
Fairfax, VA 22032
The spring Free Seminars for Family Caregivers series implements the Fairfax 50+ Action Plan directive to support caregivers so that they can continue giving. For more information on services for older adults, go to www.fairfaxcounty.gov/dfs/olderadultservices
The series is sponsored by the Fairfax County Department of Family Services' Fairfax Area Agency on Aging, Community and Recreation Services, Health Department, Library, Fairfax Long-Term Care Coordinating Council, AARP Virginia, Alzheimer's Association, Alzheimer's Family Day Center, ElderLink, Shepherd's Center of Oakton-Vienna, and Thomas West Financial Services. The program receives funding from the National Family Caregiver Support Program.
Fairfax County is committed to nondiscrimination on the basis of disability in all county programs, services and activities. To request this information in an alternate format, call Department of Family Services' Fairfax Area Agency on Aging at 703-324-5411, TTY 703-449-1186.
Fairfax County Department of Family Services
Division of Aging and Adult Services/Fairfax Area Agency on Aging
12011 Government Center Parkway, Suite 708
Fairfax, Virginia 22035-1104


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Minnesota screenwriter Scott Z. Burns did not know Joel and Ethan Coen until fairly recently, but he still feels like he owes them.
"Knowing that people from the suburb next door got to a place where they could tell stories on big black movie screens kept that idea in the back of my mind," says Burns, originally from Golden Valley (the Coens grew up in St. Louis Park). "I think they inspired a lot of people here, just as the music scene in Minnesota was so vital for a while because one person would crack open the door and then other people would start to believe they could get through."
Burns' latest movie, the sneaky "Side Effects," was directed by Steven Soderbergh, who also helmed Burns' scripts for "Contagion" (partially set in Edina) and "The Informant." At one point, Burns hoped to direct "Side Effects" himself, but he handed it off to his pal Soderbergh when he realized the Oscar winner could attract big-name stars. Which he did: Channing Tatum, Jude Law, Catherine Zeta-Jones and Rooney Mara.
"Because Steven and I had talked about it for year, and he knew what I was trying to do with the script, it felt comfortable relinquishing that position," Burns says. "I felt confident it would turn out to be the kind of cat-and-mouse psychodrama I hoped it would be. We talked about it being a really paranoid thrill ride, in some ways like 'Contagion,' where the landscape seems familiar at first and then goes off in a different direction."
The landscape of "Side Effects" is upper-crust New York. Tatum plays a man who gets out of jail for insider trading and goes home to live with his wife (Mara). But she suffers from depression (Law and Zeta-Jones are her doctors), and her illness takes the plot into surprising territory that is better left to the movie to reveal.
Burns' work on "Side Effects" dates back more than 13 years to when he snagged his first writing job on the short-lived TV series "Wonderland," set at a psychiatric hospital.
"As part of our research, all the writers spent a few months tailing psychiatrists at Bellevue in New York," Burns says. "I learned a great deal about the intersection of the law and psychiatry. I knew if I could come up with a place for them to collide, there were amazing stories."
Burns is in the unique position of being the writer on what Soderbergh has said may be his last film -- Burns insists it's not his fault -- but that doesn't mean their collaboration is over.
Soderbergh plans to paint and write, but before that, he's directing the first production of a Burns play, "The Library," which was inspired by the Columbine massacre.
The writer has plenty of other irons in the fire, too. He's working on a movie for the BBC based on a documentary called "Dark Water" and on another for Fox that he can't say anything about. And there's a project that could lead him back home to Minnesota.
"I'm a huge fan of the Hold Steady, and a few years ago, I saw them in concert. I was somehow able to use my rabid fandom to get ahold of Craig Finn, the singer, and we met up," says Burns. "He and I have been working on a script that is set in Minnesota, and it would be so much fun if we could figure out a way to pull it off. But I need to do it quickly before the Coens make all the Minnesota movies there are to make."
Speaking of which, Burns' association with the quintessential Minnesota moviemakers, the Coens, goes back all the way to summer camp -- or it could have. He was at a Jewish camp in Aitkin when a friend asked if he'd like to invest in a movie, which turned out to be the Coens' debut, "Blood Simple." The only money Burns had at the time was his tuition money, so he declined, but that might-have-been connection to the Coens pops up whenever Burns glimpses bits of "Fargo" or "A Serious Man."
"The Coens told me about working on 'Serious Man' in Minnesota, and we talked about growing up, comparing stories about rabbis and school. The name of the neighbor (in 'A Serious Man') is someone I went to summer camp with," says Burns.
All of which makes Burns something of an ideal audience for the Minnesota-set movies by the Coens.
"Oh, yeah. Their attention to detail is so right-on. When I see 'Fargo,' I go, 'Wow, I had that same bedspread when I was a kid," says Burns. "When we talked about 'A Serious Man,' the Coens were, like, 'Wow, you might be the only person in the world who understands everything in that movie.'"


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House committee OKs daily Pledge of Allegiance bill
SALEM, Ore. (AP) A House committee has approved a bill calling for the Pledge of Allegiance to be recited daily in Oregon public classrooms.
It would also require classrooms to display the American flag.
Under Oregon law, schools must give students the opportunity to say the Pledge of Allegiance at least once a week.
The bill approved unanimously on Friday would require schools to do so daily.
Students can't be compelled to say the pledge. They can remain silent. The bill wouldn't change that.
Supporters say the pledge is an important part of civic education. Critics say requiring time each day for the Pledge of Allegiance would further ostracize students who don't participate because of religious or other reasons.
The bill next goes to the House floor for a vote.
Copyright 2013 The Associated Press


text:
This appeared in Mumbai Mirror.... on the eve of Mother's Day, it's time to give Fathers a break... what say??
Wish your dear ones a very Happy Birthday exclusively with wonderful array of cakes. Send Cakes to Ghaziabad with the services provided by www.cakesdeliveryghaziabad.com offering its customers with plenty of varieties. Wishes will be so special with these tasty cakes.
Hey that's the trend- we are following the Amazonian lifestyle!
The'real' men also hate going to the 'Unisex' salons!
Happy Mothers Day!
Hi Shobhaa,
I have been a fan of yours and have read most of your books and eagerly read your columns. I have a concern to share: lately, I have seen a lot of gender stereotyping in your articles - and it surprises me, especially coming from you.
As a psychologist, I can share that research after research suggests that fathers who participate in care giving for the infant (changing nappies, bathing, feeding, playing) - along with the primary attachment figure - have several positive outcomes for the infant and mother. Yes, in earlier generations, fathers played an inactive role in care giving - therefore so many negative consequences of those children who grew up (this generation!)There is a lot of research that points out the co-relation between low self esteem & anti-social behaviour with a lack of fatherhood in the first 5 years of life.
My problem with this article is that there are too many assumptions about the roles of a 'father' and a 'male' must play and (may not play).
I miss the Shobhaa who spoke boldly about gender issues and stereotypes that helped empower both men and women!
its quite true ,i am not married but i have seen my friends marriage my friend works in a school and has to leave early and her husband has flexitime schedule so he takes care of the daughter and sends her to school(he does this because he has no choice) because when school vacation starts and my friend is at home she manages the whole thing she tells me her husband is most happiest and his moods are better bcoz he doesnt have to bother with the daughter stuff,its true.
Another story from my guy friend who works from home says he just loves the whole idea of taking care of his daughter and sending her to school it makes him happy(this type of cases are in minority) ...hmmm but in majority men dont like it,its a fact!
Boarding school showed me the other kinds of "parents" as well. Specially, mother. I Thank God for that. Or else life/ world will be so bewildered to understand the psychology of different traits of species! And my personal favorite is indeed the ones that are winner in human relationship be it a bond btw (spouses or parents-children). It takes a lot to be firm and strong rather then aggressive and superior! Although I full hearted respect the sophisticate, competitive, and cynicism of the latter! Or else there won't be such a fortune of knowledge or gifts to inherit no? Life is good~~~~ when the mind is blessed~~~~~~
Loved this article
Wow..touchwood I must be one of the few lucky women around.
Not only is my guy a great hands on dad from playing baseball with my son to changing my duaghters diapers..He actually loves it.
When he was working a lot, he would sulk and be in a bad mood if he didnt get time with the kids (not me so much :)).
He maeks them breakfast in the weekends and adds,"Parents should raise their kids and not a nanny".
My late dad was such a hands on dad too.
He picked me up from school when he got home early. despite being a bust army engineer, he helped me with my homework. Took us out, read to us, cooked on weekends.
Ands that what I remember about him even after 20 years of him pasing, its not the toys or money he made but the time he took care of me when I had a fever, When he took me to his work on weekend, when we went hiking as a teenager.
Sad to see someone of your caliber say something so sexist.Gender lines are blurring. I have a friend who is a woman VP of a bank in Manhattan and her Ivy league educated husband is a stay @ home dad. Ofcourse they can afford a nanny but who would you want your kid to run to when he/she is hurt? you or the nanny?
LOve this post :)...
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Lloyd Mats is the industry's largest aftermarket manufacturer of custom fit carpet floor mats for Mustangs, Lightnings and other great Ford models. Each floor mat kit is produced in their state of the art Northridge, California facility from materials made in the USA. Their exact fit, precision cut mats are available for Mustang & Lightning applications from the 1979 to the present and many include one-piece mats for complete passenger area coverage, trunk and cargo areas.
Lloyd manufactures custom mats specifically designed for automotive use. Their carpet mats match or compliment any OEM carpet color. Personalized embroidered designs are available on their carpet auto mat products. For the best in quality products and manufacturing at a reasonable price, trust Lloyd.


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found a new home!
Plenty of my friends are looking
for one too. Find a pet to adopt.
Simba, a Lindenhurst Chinchilla was adopted! Here's how you can benefit by looking at adoption as an option to buying a Chinchilla for sale in Lindenhurst, or seeking a Chinchilla from a breeder in Lindenhurst.


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Sutton & District AC's U15 teams were in action at the Surrey county cross-country championship at Denbies Vineyard, Dorking, last weekend.
The girls team, led over the 4.2km course by Georgia Bell (28th, 18 minutes 58 seconds), finished fifth.
Caitlin Williams (29th, 19:02), Any Hancock (47th, 20:54) and Emily Ashwood (21:27) completed the four-to-score.
The boys finished seventh, with Ben Charnock (21st, 16:35) the top man.
Not far behind were Owen Boyd (37th, 17:39), Ryan Galvin (39th, 17:52) and Ayden Wood (48th, 18:13).
Elsewhere, the senior men of Sutton Runners and Tadworth AC had a championships to forget, finishing 16th and 17th respectively in a 19-team strong field.
Tadworth AC's Paul O'Callaghan showed the best form of either team coming home in 32nd, clocking 47:04.
Sutton Runners also had a solitary figure in the women's senior race, which saw Elinor Rippard finishing in 39th in 38:19.


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It is estimated that at least 10 – 20% of American children are exposed to domestic violence in their homes. The effects on children vary widely. Some children are very resilient and continue to function in relatively healthy ways. But many children suffer from long-term effects.
711 Third Avenue - Suite 700 | New York, NY 10017 | 212-949-4800 | 212-949-4936 (Development)
The Children's Aid Society is registered as a 501(c)(3) non-profit organization


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Injured Angels slowly getting healthy
SEATTLE -- Angels lefty reliever Sean Burnett, who was unavailable on Monday and Tuesday because of tightness in his left forearm, feels fine now and was ready to pitch on Thursday if needed. The club's medical staff told Burnett the tightness was a normal byproduct of offseason surgery to remove bone spurs.
"It was just tight for a couple days," Burnett said. "It's fine now. I changed medicine and it worked."
Shortstop Erick Aybar, out since April 9 because of a bruised left heel, played five innings in extended spring training on Thursday, as scheduled, and will be reevaluated on Friday. The switch-hitting shortstop is already eligible to come off the disabled list, but Angels manager Mike Scioscia said he'll play in at least one more game in Arizona.
Third baseman Alberto Callaspo, nursing a right calf strain since April 11, is running sprints and taking part in pregame activities, but isn't expected back in the lineup at least until the team returns home on May 2. Moving side to side is still giving him pain.
"I'd prefer to wait a few days to make sure I'm healthy instead of having to be out like six weeks because I tried to come back too fast," Callaspo said in Spanish. "I want to play, but I have to be careful."
Alden Gonzalez is a reporter for MLB.com. Read his blog, Gonzo and "The Show", and follow him on Twitter @Alden_Gonzalez. This story was not subject to the approval of Major League Baseball or its clubs.


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Hi All,
I would like to know the list of possible conjunct consonants that are possible in Pali (e.g) kk, kkh, tt, ttha, mp etc.
The GNU Free font is being modified to support Pali written in Sinhala script. I just wanna make sure, all possible Pali conjuncts are supported.


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DELUXE on the East Coast, B&B Room for 2
Size40 m²
Floor No.
- Air conditioning
- Breakfast
- Air conditioning
- Breakfast
- Internet/WiFi
- Towels
Accommodation summary
|Siglap Rd, 454999 Singapore, Singapore
|Property type
|Private room
|Property ID
|Acceptance rate
|Response time
|A few hours
|Calendar updated
|A week ago
We're a retired Singapore couple with an empty nest. But we enjoy having people around. Hence the home stay.
We have three rooms for homestay guests which are very large, air-conditioned double rooms with en-suite bathrooms. Our Deluxe room rate is Singapore Dollars 140 per room night and includes breakfast. Breakfast is your choice: western, vegetarian or local, home cooked or at the market where Singaporeans eat and shop and which tourists and visitors rarely get to experience.
We serve breakfast from 8.30am to 10.00am. However, if you wish to sleep in – there's coffee and tea available when you wake up.
Enjoy our garden, relax in our living room, and use the internet. Laundry is available at a small additional charge. Stay with us and enjoy the hospitality that has become our hallmark.
Our home is located 10 minutes by taxi from Changi International Airport and bus, train and taxi services are within easy reach. We are also about 20 minutes walk from the beach and the fabulous East Coast Park. Other recreational facilities include shopping malls, cinemas and eateries of every description literally round every corner. You can get to the city centre within 15 minutes and the 'happening' Orchard Road in 20. But our home itself is in a green haven of peace and quiet.
The check - in time is 2.00 pm and the check - out time is 12.00 noon. We keep to these times for the convenience of all guests.
***Do drop us a message via the Wimdu messaging system to tell us more about yourself before making a booking so that we can consider your needs. Unfortunately we do not accept children under 7 years as our house is designed with lots of stairs making it unsafe for young children However do talk to us if you need accommodation for your children.
House rulesElectricity Usage
In the interest of environmental conservation, when the aircon is on, please keep the bathroom door closed. Please turn off the aircon and lights when you leave the room.
Some clothes that need washing? We'll do the laundry for SGD 10 a load. No ironing. The clothes will be folded or hung and placed in your room by evening, weather permitting.
Food in Singapore is irresistible to humans as well as ants, and other creepy-crawlies! So if you bring any food home, do store it in the fridge in the kitchen. Or ask us for an airtight container.
Enjoy your cigarette in the garden or on the verandah only.
|Maximum nights
|2 weeks
|Check-in after
|Check-in before
|On arrangement
|Check-out before
|Cancellation Policy
Reviews of this property
Donald und Judith sind zwei sehr warmherzige und umsorgende Gastgeber. Einfach spitze! Das Frühstück war jeden Tag anders, reichhaltig und sehr lecker. Wir können die Unterkunft wärmstens empfehlen. Gegenüber ist direkt eine Bushaltestelle; gute Anbindung an den öffentl. Nahverkehr. Und wenn's abends mal spät wird, das Taxi kostet rund 20 SID von Downtown nach Siglap.
We've been Guests at Judith & Donald House in November 2016 for three days. Both of them are really nice persons allways helpful and pleasant. Their House ist absolut marvelous and stylish. Even our room was very big and tasteful furnished. The position of the house ist quit next to a bus station from where you reach every point of interest.
Judith and Donald allways give you the feeling to be welcome in their house and they whip ervery day a different breakfast in high quality.
For us, it was nice to stay there an we would like to do it angain.
Greatings Matthias & Bianca
Our 3 nights at Judith's and Donald's house were very nice. Especially our caring hosts who helped us find our way in Singapore and the huge and tasty breakfast which varied every day, made our stay enjoyable. Thank you :)
We had a wonderful time in Singapore. The City is great and our stay by Judith and Donald was one of the highlights. Both were so helpful and friendly to us, so we felt like at home. It started with a wonderful breakfast in the morning and many good tips to enjoy Singapore. We will be very glad to come back again to this house.
Many thanks to Judith and Donald from Lena and Hans from Germany.
Unsere Erwartungen wurden voll erfüllt. Das Haus liegt zwischen Flughafen und City und ist öffentlich bestens zu erreichen. Vom Flughafen sind es nur 5 Stationen und die Innenstadt erreicht man schnell mit der grünen Linie. Die Bushaltestelle zur MRT Station ist vor der Haustüre.
Das Haus ist sehr schön, die Zimmer geschmackvoll eingerichtet und geräumig.
Das Frühstück wurde liebevoll zubereitet und hat wunderbar geschmeckt. Die Gastgeber sind sehr nette Leute, und helfen bei allen Fragen. Man fühlt sich aufgenommen. Alles in allem, wir haben uns sehr wohl gefühlt und wären gerne länger geblieben. Bei der nächsten Reise nach Singapur kommen wir gerne wieder.
Wir haben bei Judith und Donald 4 wunderbare Tage verbracht! Beide sind wirklich sehr gastfreundlich und hilfsbereit. Unser Zimmer war sauber und angemessen groß. Zum MRT ist es etwas weiter zu Fuß. Direkt vor der Wohnungstür hält jedoch ein Bus, welcher direkt zur Bahn fährt oder man nimmt für ca. 4-5 $ ein Taxi. Wir haben uns sehr wohl bei Judith und Donald gefült und kommen gerne wieder!
We enjoyed our stay with Judith and Donald very much. They welcomed us to their well appointed home in a very good neighbourhood. We have been to Singapore before staying in hotels but a home stay is a different experience and it brought us closer to the daily life in Singapore. The breakfast was excellent and varied everyday. Very good eating places close by on Upper East Coast Rd.
Overall it was a great stopover on the way back to Australia.
Judith e Donald sono una coppia gentilissima...la casa si trova in una zona residenziale di Singapore che dista un 40 minuti dalle principale attrazioni (con un bus si raggiunge la MTR e con questa si è collegati a tutta la città)!La casa è molto bella e accogliente...le colazioni varie,abbondanti e buonissime! Siamo stati molto bene e lo consigliamo sicuramente!
We stayed three nights at Judith's and Donald's home. They are great hosts and make you feel really comfortable. Their welcome was really warm and after introducing each other we got helpful information how to get to the city by public traffic, the city itself and the neighborhood. The city center (and every other place in Singapore) can be easily accessed by bus and train. To the city center you have to take first the bus (bus stop 1min walk) and switch afterwards to train.
The very spacious rooms (unlike the hotel rooms in Singapore) are very clean include an en suite shower room and are equipped both with fans as well as air cons. Every morning we were surprised by a very nice breakfast which varied every day.
We can highly recommend Judith and Donald as your host in Singapore which is more than an alternative to the hotels. We did really enjoy our stay there.
- Quality assured accommodation
- Every host is verified by telephone
- Secure payment via SSL encryption


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"This is pretty critical to our season. Being at home, and this is two conference teams that technically I think we should beat, but I know we are equal," Ball said. "Boy, if you lose these and don't get off to a good start. Then we go on the road to Ohio State, Ball State and Loyola. Holy cow it would be a long next few weeks."
IPFW (3-2, 0-0 MIVA) opens its MIVA season against Lindenwood at 7 p.m. Friday at the Gates Center before concluding its three-match homestand against Quincy at 7 p.m. Saturday.
Lindenwood (0-3, 0-2 MIVA) in its inaugural season in the MIVA after transitioning from NAIA to NCAA Division II opened conference play last weekend with two losses to No. 10 Ohio State. In addition, the Lions were projected to finish the MIVA in sixth place in the conference preseason coaches poll — one spot behind the Mastodons.
Quincy (4-3, 0-0 MIVA) was picked to finish in last place in the preseason MIVA poll and enters this weekend on a 20-match losing streak against IPFW dating back to 2003.
Despite it being early in the season, All-MIVA outside attacker Eddie Rivera said every IPFW player while preparing for these two matches this week was aware of these matches' importance.
"We are going to be facing really good teams," Rivera said. "It's more important in hopes that it will give us more confidence, especially playing a team like Lindenwood."
IPFW begins MIVA play having won three of its last four matches in non-conference play — including a sweep against Lourdes, a NAIA school, last week.
Ball said the five non-conference matches leading up to the MIVA opener was invaluable experience for his young team that features four first-year starters. The coach also said the team's inexperience resulted in its two losses to St. Francis (Pa.) and the New Jersey Institute of Technology.
"We just let down and made rookie errors," Ball said. "Hopefully we'll be pretty good by the end."
If IPFW can win its two MIVA matches this weekend it would be the first steps to finishing the regular season in the top half of the conference standings and earning the right to host to a MIVA Tournament match. IPFW has not had a home MIVA Tournament match since 2007 — the last year the Mastodons also won postseason match as they won the conference and advanced to the NCAA Tournament championship match.
Rivera said having a home postseason match is one of the goals for IPFW. He also said he feels the Mastodons have the potential to surprise a lot of people in the MIVA this season.
"We know we're the underdog, but that doesn't mean anything in conference," Rivera said.


text:
An Armful of Predictions for 2013
In this piece, I will recap my 2013 predictions that I summarized Monday on Real Money Pro, when I covered the Daily Diary for Doug "Orson Welles" Kass. My key investment positions in 2013 are extensions of the themes I have been espousing for the last few months, so they should not be overly surprising. I hope they fall under the category of "insightful" and, to some extent, "common sense."
1. The federal budget battle continues unabated. This month's machinations are a non-solution. The U.S. still faces a trillion-dollar deficit, and the negotiations will be rehashed several times in 2013. In fact, by Valentine's Day the past month's discussions will be repeated with even more vitriol. The bill passed by the Senate defers the sequestration for two months, meaning the real battle over spending is yet to come. Even worse, although this bill "balances" $41 in tax increases for every $1 in spending cuts, President Obama has already vowed that any spending cuts will need to be accompanied by even more tax increases. No matter which side you are on, the reality is that this will create a higher-than-usual volatility in equity markets -- an argument to get long the CBOE Volatility Index (VIX)....425 more words left in this article. To read them, just click below and try Real Money FREE for 14 days.
There's no substitute for a trading floor to get great ideas, so Jim Cramer created a better one at Real Money and blogs there exclusively. We then added legendary hedge fund manager, Doug Kass, with his exclusive Daily Diary and best investing ideas. Staffed with more than 4 dozen investing pros, money managers, journalists and analysts, Real Money Pro gives you a flood of opinions, analysis and actionable trading advice found nowhere else, and allows you to interact directly with each expert.
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text:
Wiltshire Council deputy leader John Thomson believes the council did the best it could to plan for the floods which affected Malmes-bury and north Wiltshire but said it was exceptional weather.
He said the council delivered more than 4,000 sandbags across the county and said sandbags were delivered to Malmesbury before the flooding occurred.
Coun Thomson, who represents Sherston, said four inches of rain fell in four days in Pinkney, compared to one inch in the whole of March.
He said: "We did everything we could beforehand. The trouble was the fields were saturated and the water ran into the river and it roared down into Malmesbury.
"Everyone was so surprised by the speed at which the water rose.
"A lot of the houses in Malmesbury have professionally fitted flood gates and they were overwhelmed. People in Malmesbury have never seen the river so high.
"All the agencies did brilliantly, the fire, police, ambulance and the council. It was a huge challenge and we had teams working 24 hours. We had 17 highways teams clearing trees off roads and pumping water away.
"I think we have done quite well. I am sure we could have done better and we will be reviewing what we did. When you are flooded it is never enough. Walking through raw sewage in your home is terrible.
"Everything that was humanly possible was done. It was exceptional weather."
He said the council would talk to the Environment Agency to see if anything can be done with the River Avon to prevent flooding.
Coun Thomson is also chairman of Malmesbury Area Board and under delegated powers he has approved a £500 grant to Malmesbury Football Club whose ground was flooded.
The Area Board will also use money in its budget to buy second hand cookers and fridges to help families affected by the floods.
Flooding minister Richard Benyon visited Malmesbury on Sunday to see the flood damage for himself.
He said: "In Malmes-bury last weekend, I saw for myself the absolute devastation the flooding has brought to people's homes. I can only pay tribute to the admirable way the community has pulled together at this miserable time, and to the tireless efforts of the local Environment Agency and emergency services to keep people safe and prevent further flood damage.
"We're doing all we can to protect homes and businesses from flooding, and expect to protect another 145,000 properties by 2015."