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The Watkins Visiting Artists Series (VAS) is an annual yearlong program that welcomes nationally and internationally recognized fine artists, designers, filmmakers, educators and critics to the campus and the community. The guest artists, whose work crosses many disciplinary boundaries, give public presentations, sharing their expertise and perspectives on their careers and providing insight into issues facing contemporary artists and designers.
Award-winning documentary photographer Carolyn Drake (Taylor-Lange Documentary Prize, Guggenheim and Fulbright Fellowships, World Press Photo, POYi), works globally on personal projects and assigned commissions that explore the effects of modernity on individual and cultural freedoms. Her photographs demonstrate the power of art in documenting the lives of people living under conditions of precariousness and political repression, and through this work, she allows them to speak with their own voices. Read more.
All of the individuals in the 2015 Visiting Artists Series at Watkins explore the role of the artist as a critical intellectual. Not only have these artists shifted the perimeters of their fields by exploring new media and new forms, but they have also contributed to some of the most important debates of the contemporary era, including addressing the rights and responsibilities of artists in an era where creative people are becoming instruments of branding and gentrification.
The 2015 Watkins Visiting Artists Series is funded in part by a grant from Humanities Tennessee, an independent affiliate of the National Endowment for the Humanities.
Letterer, illustrator and type designer Jessica Hische–at the age of 31, one of the most influential graphic designers in the world–launches the 2015 Watkins Visiting Artists Series. For more information, read the news story.
Ashley Hunt is a Los Angeles-based writer and artist best known for his activist projects in video, photography and graphic design which engage the ideas of social movements, modes of learning and public speech. His work is often concerned with questions of power and the ways that some people have more, others have less, and what can be done about that. Among his most celebrated works are his ongoing video series on the prison system, entitled The Corrections Documentary Project, and his Prison Maps. His work has been screened and exhibited at the P.S.1/MOMA, the Tate Modern, the Museum of Modern Art, the Contemporary Museum in Baltimore, and the Martin Luther King Jr. Center in Atlanta. He is Co-Director of the Program in Photography and Media at the California Institute of the Arts (CalArts). Read the news story.
Martha Rosler is a Brooklyn-based artist and writer. Her work includes video, installation and performance. She is best known for a series of photomontages entitled House Beautiful: Bringing the War Home (1967-1972) and for her early explorations of video as a medium, especially her famous Semiotics of the Kitchen (1975). Her photo-conceptualist project The Bowery in Two Inadequate Descriptive Systems (1975-1976) offered an important critical perspective on documentary photography in light of conceptual art. She is also a celebrated writer and critical voice, and has published over 15 books of her writings and art. Her collected essays, Decoys and Disruptions, was published by MIT Press in 2004. She has taught at Rutgers University and at Städelschule in Frankfurt, Germany.
Read more here
Renowned for his writings on postwar American art and queer art history, Katz curated the much-discussed 2010-11 exhibition Hide/Seek: Difference and Desire in American Portraiture at the National Portrait Gallery in Washington, D.C. He is also a co-founder of Queer Nation in San Francisco, founder of the Harvey Milk Institute, and former director of the Larry Kramer Initiative for Gay and Lesbian Studies at Yale University. His writings have appeared in Art in America, Art & Text, Art History, Art Journal, and numerous other publications. He is co-author with Moira Roth of Difference/Indifference: Musings on Duchamp and Cage.
Katz is currently an associate professor and director of the Ph.D. program in Visual Studies at University of Buffalo. He has previously taught at Smith College, Stony Brook University, University of Amsterdam, and Yale University. At the City College of San Francisco, during the 1990s, he was the first full-time, tenured faculty member in gay and lesbian studies in the United States.
Katz's scholarly work addresses why the American avant-garde in the Cold War era came to be dominated and defined by queer artists who remained silent about their sexuality in what was perhaps the single most homophobic decade in this nation's history. His research and writing has focused on composer John Cage and painters Robert Rauschenberg and Jasper Johns, although he also has written about poet Frank O'Hara, French theorist and radical feminist Monique Wittig, artists Agnes Martin, David Hockney, Andy Warhol, Keith Haring and others. Currently, he is co-curating "AIDS/Art/America," a major 2014 international touring exhibition offering the first examination of the ways AIDS shifted post-modernist premises in the art world.
Painter R. H. Quaytman, whose work addresses the critical and institutional contexts of painting, will speak at Watkins on her first visit to Nashville. The lecture, second in the 2013-14 Visiting Artists Series, is free and open to the public.
In her recent work, the New York-based Quaytman has placed the language of painting into dialogue with the real world contexts of the museums or galleries where it appears. Her work aligns the aesthetics of painting with more austere and intellectual traditions of conceptual art and institutional critique.
About the artist
R. H. Quaytman was born in 1961 in Boston, and lives and works in New York. She received her B.A. in painting from Bard College (1983), and attended the post-graduate program in painting at the National College of Art & Design in Dublin (1984) and the Institut des Hautes Études en Arts Plastiques in Paris (1989). She was subsequently awarded a 2001 Rome Prize Fellowship. Quaytman was director of Orchard, a cooperative gallery in New York, open from 2005 to 2008, and is currently faculty of Milton Avery Graduate School of the Arts, Bard College.
Quaytman incorporates optical abstractions, silkscreened photographs, diamond dust layers, and hand-painted trompe l'oeil elements into her works. Using these diverse techniques, she weaves personal, art historical, and formal narratives to explore the many contexts in which painting can be seen and understood. Presented in groups she considers "chapters," Quaytman's works invite the viewer to look from one painting to another, considering individual works within the context of the group.
Solo exhibitions of her work have been mounted by Galerie Nathalie Obadia, Paris; The Renaissance Society, Chicago; Museum Abteiberg, Monchengladbach, Germany; Gladstone Gallery, Brussels; Kunsthalle Basel, Switzerland; Institute of Contemporary Art, Boston; Freidrich Pretzel Gallery and Miguel Abreu Gallery, New York; Vilma Gold Gallery, London; Neuberger Museum, Purchase, New York; and Museum of Modern Art, San Francisco, among others.
In the past decade she has participated in more than 60 group exhibitions in galleries and museums throughout the world, including London, Paris, Vienna, Warsaw, Rome, Berlin, Venice, Brussels, Antwerp, Stockholm, New York City, Los Angeles, San Francisco, St. Louis and Ft. Worth. She was also included in the 2011 Venice Biennale and the 2010 Whitney Biennial.
Quaytman is the author of Allegorical Decoys (MER Press, 2008), inspired by her time as director of the Manhattan cooperative gallery Orchard, and Spine (Sternberg Press, 2011), which brings together all her paintings produced since 2001, the year she began conceiving and organizing her output in chapters (includes 20 chapters total). She is also a contributor to Corrected Slogans: Reading and Writing Conceptualism (Triple Canopy, 2013), a collection of conversations with innovative artists and poets addressing conceptual practices in contemporary art and poetry.
Nick Briz and Jon Satrom
Monday, March 3, 2014
6 p.m.
Watkins Theater
reception for Visiting Artists Exhibition RipZipRARLANd to follow from 7 to 9 p.m.
Free parking in campus lot
Chicago-based new media artists Nick Briz and Jon Satrom will speak at Watkins College of Art, Design & Film on Monday, March 3, in the final installment of the Watkins Visiting Artists Series. Their remarks about the ethics of saving/sharing, experimentation, conscious copying, hacking and collaboration will begin at 6 p.m. in the Watkins Theater, followed immediately by a reception to celebrate the gallery show RipZipRARLANd, an exhibition of ripped work from artists working in a variety of genres including net.art, glitch art, video, and dirty new media.
The theme of the exhibition is based on the infinitely copyable nature of new media, lossy and corrupt works, and the intentions involved in their preservation and distribution. The show will be on display in the Brownlee O. Currey, Jr. Gallery on campus through March 20.
RipZipRARLANd (which takes its combination name from several new media terms) is a utopist local area network inspired by experimental new media art, and guests are invited to bring their digital files to copy to the RipZipRARLANd Local Area Network Archive installed at Watkins for the run of the show.
Recognized internationally as leaders in the counter new media art movement known as glitch, Briz and Satrom undermine interfaces, bend data and provoke glitches in the arena of digital media. Their practices have grown out of the infinite copy-ability of data and inevitable decay of digital media. They hack, reclaim, remix and share in an effort to promote and preserve a genre/medium/culture.
About RipZipRARLANd
As [users/artists] we consider ourselves [creators/producers], however, in the eyes of contemporary (networked) corporations, we are the product being sold for billions of dollars. These wide-spread software-as-service models don't trade in their technology as much as they trade in humans. SoftwARE iz Humans.
Nick Briz is a new media artist, educator and organizer based in Chicago. He is an active participant in digital culture and experimental new media, specifically through his work/research/writing on glitch art, remix-culture and digital literacy, and he regularly organizes events related to these theories/practices as well as teaching at the Marwen Foundation and the School of the Art Institute of Chicago, where he is Instructor in Contemporary Practices. His work has been shown internationally at festivals and institutions such as the FILE Media Arts Festival (Rio de Janeiro), the Images Festival (Toronto), the Museum of Contemporary Art Chicago, the Museum of Moving Image (NYC), Furtherfield Gallery (London); Museo De Arte Contemporaneo de Caracas, and LEAP Berlin. Briz has been featured in on/off-line publications including Rhizome.org, Furtherfield.org, the Creators Project, Creativity Online, PSFK, and Neural Magazine. He works collaboratively/commercially as Branger_Briz, a digital interactive agency, and is co-founder/co-organizer of the GLI.TC/H international conference/festival/ gathering. His work is distributed through Video Out Distribution (Vancouver) as well as openly and freely on the web. Briz holds a BFA from the University of Central Florida and an MFA from SAIC. See more at nickbriz.com
Jon Satrom is a Chicago-based artist, educator and designer who performs realtime audio/video, makes kludgey work-flows, creates colorful glitch-ware, and enjoys working within collaborative projects and open systems. He spends his days fixing things and making things work, and spends his evenings breaking things and searching for the unique blips inherent to the systems he explores and exploits. By over-clocking everyday digital tools, Satrom kludges abandonware, funware, necroware, and artware into extended-dirty-glitchy-systems for performance, execution, and collaboration. His time-based works have been enjoyed on screens of all sizes; his Prepared Desktop has been performed in many localizations. Satrom organizes, develops, and performs with I ♥ PRESETS, poxparty, and GLI.TC/H, in addition to other initiatives with talented dirty new-media comrades. Currently Instructor in New Media at the School of the Art Institute of Chicago, Satrom holds a BFA in Video/Sound/Art and Technology from SAIC. See more at jonsatrom.com and watch his TedxDePaulU talk, "Creative Problem Creating" • http://www.youtube.com/watch?v=OFwNtXpuMq4
Watkins hosts many artists, designers, and filmmakers to come and speak directly to the students and also to the public at large. Below is a list of just some of these talented people who, in recent years, have shared their time, their stories, and their advice.
Natalia Almada – Filmmaker
Gail Anderson – Creative Director of Design at SpotCo. NYC
Joel Anderson – Anderson Design Group
Ann Beatts – Screenwriter
David Bennett – CMT Lead Animator
Gina Binkley – Alter Ego Design, Illustration and Photography
John Henry Blatter – Media and Sound Artist
Wayne Brezinka – Design and Illustration
Shawn Brown – Photographer
David Carson – Author, Typographer, Designer
Keith Carter – Photographer
Barry Cook – Disney Animator
Aisha Cousins – Visual Artist
Jessica Davis – Interior Designer
Bob Delevante – Designer and Photographer
Mike Delevante – Owner, Delevante Creative
Dean Dixon – Photographer
Susan Eaddy –Children's Author and Illustrator
Vern Evans – Photographer
Harrell Fletcher – Social Practice Artist
Phil Foster – Illustrator
Travis Foster – Illustrator
Marcelle Guilbeau – Interior Designer
Beth Haley – Interior Designer
Helen Hannah – Interior Designer
David Hilliard – Photographer
Rocky Horton – Visual Artist
Nancy Inman – Designer
Terri Jones – Visual Artist
Rainey Kirk – Illustrator
Miwon Kwon – Art Historian & Critic
Liz Magic Laser – Video and Performance Artist
Deborah Luster – Photographer
David Macauley – Author, Illustrator
Laray Mayfield – Film Casting Director
David McClister – Photographer/Director
Bryce McCloud – Illustrator and Designer
Kim Michaud – Interior Designer
Greg Miller – Photographer
Zach Provonchee – Architect
R. H. Quaytman – Painter
Dan Read – Hollywood Makeup Artist
Lucie Rice – Illustrator
Artemio Rodriguez – Printmaker & Illustrator
Bethany Rooney – Television Director
Bill Ross – Children's Author and Illustrator
Rebecca Ruegger – Painter and Illustrator
Michael Rutherford – Photographer
Chris Sickels – Animator and Children's Book Illustrator
Jeff Silva – Visual Artist
Julie Sola – Printmaker and Designer
T. L. Solein – Painter
Alec Soth – Photographer
Robert Stone – Film Producer
Jock Sturges – Photographer
Sheila Turner – Photographer
Wayne White – Painter and Sculpture
Elizabeth Williams – Art Director


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Two Archer men who made a deal to sell cocaine and a shotgun to a drug task force informant tried the old bait-and-switch routine using crack cocaine and no gun, but they were still arrested on a variety of drug charges Wednesday, Oct. 24, by the Levy County Joint Drug Task Force, according to a Sheriff's Office press release
The following information was taken from Levy Count Sheriff's Office arrest reports:
Julian Christopher Howard, 32, and Arnett Clarence Bryant Jr., 30, both of Archer, were arrested in the Raleigh area of Levy County on Thursday by the Levy County Sheriff's Office and the U.S. Marshals Service Florida Regional Fugitive Task Force on drug charges in an investigation that began in February.
Levy County Sheriff's Office Drug Task Force started the investigation with Howard, considered a mid-level drug dealer who is is known to sell crack cocaine, powder cocaine and marijuana.
The Levy County Sheriff's Office reports the following arrests:
Copyright © 2017
The Chiefland Citizen is your source for local news, sports, events, and information in Levy County and Chiefland Florida, and the surrounding area.

subset: commoncrawl


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1. Tell us a little about yourself. (If you'd like, tell your name, where you live, and what you do for a living. If not, just share something interesting.)
2. How did you find Kalyn's Kitchen and how long have you been reading this blog?
3. What are some things you'd be sure to eat if you were visiting San Francisco?
4. Where's the best place you ever went for a vacation and what did you eat there?
5. What's the next thing you'll be cooking in your own kitchen?
Thanks for taking time to participate in the survey! I'll be back soon, hopefully with lots of new food ideas from San Francisco and maybe a few photos.
P.S. If I have time, I'll check in with a comment once in a while and tell you what I'm doing!


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Neurocognitive Effects and Tolerability of Efavirenz in Aging HIV-infected Individuals ("SHAC Neuro Study")
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
|Behavioral: Neuropsychological testing
|Study Type:
|Study Design:
|Observational Model: Cohort
Time Perspective: Prospective
|Official Title:
|Neurocognitive Effects and Tolerability of Efavirenz in Aging HIV-infected Individuals ("SHAC Neuro Study")
- Compare a composite measure of neurocognitive function in older individuals on EFV-containing ART vs. non-EFV-containing ART. [ Time Frame: one year ]
Neurocognitive function will be assessed using a detailed battery of neuropsychologic tests including timed gait, grooved pegboard with the dominant and non-dominant hands, the Rey auditory verbal learning test trials I-VII, trail making parts A and B, Rey auditory verbal learning test trial VIII 30-min delay, controlled oral word association test and paced auditory serial addition task. This battery has been used extensively in previous studies in HIV. Z-scores for each neurocognitive test, based on age-adjusted norms, and a composite Z-score will be calculated. The Z-score represents the amount, in standard deviation units, that the subject's test result deviates from population means.
In addition to neurocognitive function, the level of depression and anxiety and sleep quality will be evaluated using validated instruments.
|Study Start Date:
|December 2013
|Study Completion Date:
|December 2015
|Primary Completion Date:
|December 2015 (Final data collection date for primary outcome measure)
|Assigned Interventions
EFV containing ARV regimen
Pts on Efavirenz containing ARV regimen will have neuropsychological testing performed
Behavioral: Neuropsychological testing
Neuropsychological testing
Non -EFV ontaning ARV regimen
Pts on a Non-Efavirenz containing ARVregimen will have neuropsychological testing measures performed
Behavioral: Neuropsychological testing
Neuropsychological testing
Detailed Description:
With the aging of the HIV-infected population in the United States and elsewhere, neurocognitive dysfunction will likely become an increasingly common problem. Older individuals could be at increased risk for efavirenz-associated adverse effects due to impaired metabolism, increased drug-drug interactions, and lower physiologic reserve, but there are few data on the long-term safety of efavirenz (and other antiretrovirals) in older individuals with HIV.
The Stanford HIV Aging Cohort (SHAC) is an ideal setting to study potential neurologic effects of antiretrovirals in aging patients. SHAC is an ongoing longitudinal study initiated in 2008 to evaluate aging in virologically-suppressed HIV-infected individuals. The cohort is supported through multiple grants including a grant from the State of California's HIV Research Program as well as a NIH supplemental grant. As of September 2013, approximately 150 virologically-suppressed HIV-infected adults have been enrolled. In addition to enrolling patients with good adherence to ART, the cohort purposefully excludes subjects with active substance abuse, unstable medical conditions, and psychiatric illnesses to limit potential confounding the study end points. Recently, an NIH supplemental grant (AI069556) was received which will expand the SHAC to 300 HIV-infected subjects. The median age of the subjects in the cohort is in the mid-50's allowing an ample number of older subjects for our planned studies.
|Ages Eligible for Study:
|50 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
|Sampling Method:
|Probability Sample
Inclusion Criteria:
- Enrollment into SHAC (Stanford HIV Aging cohort)
- Age over 50 years of age
- Stable antiretroviral therapy containing EFV- or PI-containing ART (but not both) for at least 6 months
- HIV RNA levels of <200 copies/mL for at least 6 months excluding blips (i.e., a single measurement between 200-500 copies/mL preceded and followed by measurements of <200 copies/mL) while on ART.
Exclusion Criteria:
- Completed treatment for any acute systemic infection (other than HIV-1) less than four weeks before study entry
- Any active brain infection (except for HIV-1), brain neoplasm, or space-occupying brain lesion.
- Any active psychiatric illness including schizophrenia, severe depression, or severe bipolar affective disorder that, in the opinion of the investigator, could confound the analysis of the neuropsychological test results.
- Active drug or alcohol abuse that, in the investigator's opinion, could prevent compliance with study procedures or confound the analysis of study endpoints.
- Hospitalization within 30 days of study entry
- Receipt of systemic chemotherapy within 30 days of study entry
- Unable to provide informed consent
Please refer to this study by its ClinicalTrials.gov identifier: NCT01985399
|United States, California
|Stanford University AIDS Clinical Trials Unit
|Palo Alto, California, United States, 94304
|Principal Investigator:
|Philip Grant, MD
|Stanford University
|Responsible Party:
|Philip Grant, Principle Investigator, Stanford University
|ClinicalTrials.gov Identifier:
|NCT01985399 History of Changes
|Other Study ID Numbers:
SHAC Neuro Study
|Study First Received:
|November 4, 2013
|Last Updated:
|October 13, 2016
Keywords provided by Philip Grant, Stanford University:
Additional relevant MeSH terms:
Reverse Transcriptase Inhibitors
Nucleic Acid Synthesis Inhibitors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Anti-Retroviral Agents
Antiviral Agents
Anti-Infective Agents
Cytochrome P-450 CYP2C9 Inhibitors
Cytochrome P-450 Enzyme Inhibitors
Cytochrome P-450 CYP2C19 Inhibitors
Cytochrome P-450 CYP2B6 Inducers
Cytochrome P-450 Enzyme Inducers
Cytochrome P-450 CYP3A Inducers
ClinicalTrials.gov processed this record on September 20, 2017


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Damn JR! Just point out what I'm missing in my bag why don't ya!
... Although, you did nail it spot on for the one disc I seemed to be missing in my current line up of disc. There was one hole I wished I had a very OS mid/utility for this past weekend and I paid for it with a bogey.... both rounds. I did really well IMO tho, 53/55/53/54 to finish 3 under for the tournament (tied for 3rd). I'm extremely glad I threw the stratus in the bag. Was VERY handy this weekend actually.
After seeing some of these other players keeping up distance wise with blizzard disc to my PD's, I've decided to try a few of them out to see how they fare for me. With my winnings from the tourney, I picked up a blizzard Wraith and Destroyer (155/153, bubbles in rim only) to play around with. I assume I should look for an US compliment (maybe Katana) to them if one should make my bag. Should I consider picking up distance drivers in normal weights/plastics too?
I need to find that OS mid/utility as well.... suggestions? (XXX, FB, Banshee, Drone, Zone, Whippet, etc...)


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Ithaca College to Host Talk on Latina Immigrant Domestic Workers
ITHACA, NY — The Ithaca College Center for the Study of Culture, Race, and Ethnicity (CSCRE) will continue the celebration of its 10th anniversary on Wednesday, Feb. 23, with a presentation titled "Domésticas Demanding Dignity: Latina Immigrant Workers and the Racial Politics of Domestic Service." The free public talk by Verónica Martínez-Matsuda will be held at 7 p.m. in Clark Lounge, Egbert Hall.
Martínez-Matsuda studies the intersections between labor and citizenship, particularly immigrants' social movements and cross-border organizing efforts for improved living and working conditions. Her current research examines the role of the Migratory Labor Camp Program, established and managed by the U.S. Government during the late 1930s and early 1940s, in the lives of migrant farm worker families.
Currently a visiting professor in the School of Industrial and Labor Relations at Cornell University, Martínez-Matsuda has held fellowship positions at Bryn Mawr College, Rhodes College and the Smithsonian Institution's National Museum of American History. She holds a Ph.D. in Borderlands/U.S. History from the University of Texas at Austin. Her dissertation was awarded the Barnes F. Lathrop Prize for Best Dissertation in the Department of History and named a runner up for the Labor History Best Dissertation Prize by the journal "Labor History."
The presentation is part of the annual discussion series hosted by the CSCRE. Titled "Centering the Margins," the series this year is offering a retrospect on the center's activities over the past decade as well as a look ahead to its future.
For more information, visit /cscre/discussionseries/.
Originally published in IC News: Ithaca College to Host Talk on Latina Immigrant Domestic Workers.


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Last Week's Results
Down to the Wire: The Griffins will complete a three-game homestand and try to maintain their late-season surge this Wednesday at 7 p.m., when they stage an intradivisional battle against Rochester at Van Andel Arena. If Grand Rapids beats Rochester on Winning Wednesday, each fan in attendance will be able to redeem their ticket stub for a free ticket to the Griffins vs. Amerks game next Wednesday, April 7. In addition, fans who present their Grand Rapids Public Library card or Kent District Library card at the Van Andel Arena box office on the night of the game or at The Zone anytime during the store's regular business hours can purchase a lower bowl ticket for just $10 - a savings of $7! Limit four tickets per card per person.
Close the Gap: With seven games remaining on their schedule, the Griffins trail fourth-place Manitoba by seven points in the race for the final playoff spot in the North Division. Grand Rapids has already trimmed seven points off what was a 14-point Moose lead by going 6-1-1-2 in its last 10 games, while Manitoba has posted a 4-4-0-0 mark over the same stretch.
Running With the Big Dogs: Since their current 6-1-1-2 run began on March 5, the Griffins have suffered the fewest regulation losses of any AHL team. The next-best marks during that stretch belong to AHL-leading Hershey (9-2-0-1), Western Conference-leading Hamilton (9-2-0-1), Texas (10-2-0-0) and Bridgeport (9-2-1-0). Grand Rapids has earned as many wins and points (six and 15) in its last 10 games as it did during the preceding 27-game stretch from Jan. 3-March 4 (6-18-2-1, 15 pts.).
Destination Abbotsford: This Friday and Saturday, the Griffins will make their first-ever visits to the Abbotsford Entertainment & Sports Centre in British Columbia, marking the 49th arena, 41st city and sixth Canadian province in which they've played since their 1996 inception (including Grand Rapids and Van Andel Arena)…The Griffins have not played a game in the Pacific Time Zone since Nov. 24, 2004, when they beat the Cincinnati Mighty Ducks 4-3 in a shootout at the Arrowhead Pond of Anaheim, one of three Pacific-Time cities in which they've previously played (Las Vegas and Long Beach)…At 1,791 miles from Grand Rapids, Abbotsford will mark the third-farthest city in which the Griffins have played a game, trailing Long Beach (1,859) and Anaheim (1,844) and just out-distancing Las Vegas (1,633) and St. John's (1,621).
Packing Them In: After Grand Rapids welcomed a total of 20,947 fans (96.7% capacity) to Van Andel Arena on Friday and Saturday, the Griffins' fourth-ranked attendance average has eclipsed the 7,000-mark for the season (7,046). Including its March 6 sellout (10,834) against Manitoba, Grand Rapids has logged three straight home crowds of 10,000-plus.
On the Plus Side: Francis Pare leads Grand Rapids with a plus-19 rating, a figure nearly twice that of the next-best Griffin (Jan Mursak at plus-10). Pare, whose plus-23 rating last season was the highest for a Griffin since 2005-06, is on track to become the first player in franchise history to lead the team in plus/minus in two different seasons, much less consecutive campaigns. His career plus-42 rating currently places him ninth on the Griffins' all-time list.
Scoring Outburst: Five of the Griffins' six goals in their 6-3 win over Milwaukee on Friday came during the third period, tying their season high for a single frame and marking their most in a home stanza since they scored five times in the third period of an 8-4 win over Rochester on Jan. 31, 2009…Combined with their four goals on Saturday against Texas, the Griffins' 10 goals were their most in consecutive games since Dec. 13-15.
Who's Hot?: Jordan Owens scored his first goal as a Griffin on Friday against Milwaukee, part of a three-point night (1-2—3)…Jamie Tardif scored two goals, including the game-winner, and contributed an assist and a plus-three rating against the Admirals, before tallying the game-tying marker on Saturday to help the Griffins earn a point against Texas…Cory Emmerton (1-2—3), John Vigilante (0-3—3) and Jan Mursak (2-0—2) also have points in consecutive games…Mattias Ritola owns a three-game point streak (1-3—4) and has factored into the scoring in 14 of the last 21 games (6-12—18)…Jeremy Williams also has a three-game point streak (2-2—4) along with points in five of the last six outings (3-3—6)…Daniel Larsson is 5-2-1 with a 2.46 GAA and a 0.910 save percentage so far during March.
If Only We Played in the North Division. Oh, Wait…: Of their 73 games thus far, the Griffins have played only 29 within the North Division, compiling a solid 15-11-1-2 mark (0.569) against their theoretical rivals. By contrast, they've staged 44 interdivisional contests against the West with a 16-24-2-2 record (0.409) to show for it.
Playhouse Raffle Ends April 9: The season-long charitable raffle for the Griffins/Van Andel Arena playhouse has less than two weeks remaining. This spectacular custom-built playhouse, donated by Out on a Limb Playhouses of Grand Haven, includes amenities such as a 22" HD television, a Sony PlayStation 3 game system with EA Sports' NHL 2010 video game, two stadium-style seats, a custom-made bench modeled after those in the Griffins' locker room, an "ice-rink" floor with dasher boards, a Griffins hanging scoreboard light, a built-in street hockey net and much more! The winner will also receive free delivery and site preparation/landscaping within 50 miles of Grand Rapids. Raffle tickets are available for $5 each or five for $20 and may be purchased at the playhouse display in the Van Andel Arena lobby before any Griffins game, on the concourse during intermission, or at griffinshockey.com/playhouse. The drawing will be held during the second intermission of the Griffins' regular season home finale on April 9, and all proceeds will benefit the Griffins Youth Foundation.
Scouting Report
Wed., March 31 vs. Rochester Americans (40-31-2-1) – Van Andel Arena – 7 p.m.
Fri., April 2 at Abbotsford Heat (34-28-5-6) – Abbotsford Entertainment & Sports Centre – 10:30 p.m.
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text:
by Mitch Garnaat
Over the past year or so, Amazon has been expanding it's line of infrastructural web services. Amazon CEO Jeff Bezos likes to call this collection of services muck, meaning these kinds of services are difficult to build in a scalable manner. That's exactly what this article will focus on: combining three of these scalable services from AWS using an architecture that allows us to build robust, reliable, and scalable compute services. While the basic architecture described here could be applied to many different application areas, this article will focus on building a service to solve a specific problem that I run into regularly: video format conversion.
Like most people today, I have made the transition from film cameras to digital cameras. One of the cool things that many digital cameras today can do is shoot video in addition to still photos. So now I have hundreds of these videos, all in AVI format, sitting around on my hard drive. What I really want to be able to do is load these videos up on my video iPod so I can enjoy them and share them easily. The problem is that the iPod doesn't play AVI format videos. It wants it's videos in MPEG4 format.
In this article, we're going to build a video conversion service using the AWS building blocks. This service accepts AVI format video files as an input and produces MPEG4 files as an output. Not only will this service be able to convert all of my videos, it could easily be scaled to handle mass video conversion for thousands of users or be used as a component in a larger media management application.
Before We Begin
The architecture that I describe in this article could be applied to any programming language, but, for my example, I'm going to use Python. There are two main reasons for this:
- Python has been my favorite programming language since the days of Python 0.9 and it's a great choice for mashing up various services to create new services.
- I've already developed a Python language library called boto that provides interfaces into all three of the Amazon Web Services we are going to use in this article.
We're going to be taking advantage of boto on both the server side and the client side of this project but if you are interested in building similar services in other programming languages, check out the AWS forums and Resource Center. There are lot's of libraries available for many different languages.
Let's get started!
The Big Three
The three services we will focus on in this article are:
- Amazon Elastic Compute Cloud (EC2) for scalable compute resources
- Amazon Simple Storage Service (Amazon S3) for unlimited, reliable storage
- Amazon Simple Queue Service (SQS) for reliable messaging and loose coupling
We could build a conversion service like the one I describe above without using any of these Amazon Web Services. Our little server sitting on the web may work for us, but what happens if our friends and family decide they want to use it? Or, heaven forbid, what happens if someone blogs about it, the right people find out, and our little service gets Digg'ed or Slashdot'ed? Where are we going to store all of that uploaded video? How are we going to handle the compute-intensive video conversion? How are we even going to handle the bandwidth required to handle the requests? We're not. We're building our service leveraging these building blocks from AWS so we can end up with a service that will be easy to construct, inexpensive to operate, and able to scale to meet virually any demand.
Putting the Pieces Together
The diagram below shows the basic architecture of the service we are building.
Amazon S3 is the perfect place to store the video files to be converted as well as any output files generated by our conversion service. In addition to being fast and reliable, we will never have to worry about our service running out of disk space.
For the instructions, we want a place where different clients can store the information and know that the instructions will be delivered to our service. Our service wants to be able to read one set of instructions at a time, in roughly the order in which they were stored. This ensures that work is done in a timely and fair manner. Fortunately for us, that's exactly what SQS provides us. Think of it as e-mail (or more generally, messaging) for services. And again, we won't have to worry about scalability, availability, or reliability.
Finally, we need a way to actually perform the video conversion. This is where EC2 comes in. EC2 provides elastic computing resources. With a single API call to EC2 I can create a brand new server to do my bidding. In fact, I can create dozens of them. And when the work is done, I can make them go away just as quickly and easily. No more trips to Fry's! Well, okay, maybe we will still find a reason to go to Fry's but we definitely won't have to go to buy servers for our conversion service. EC2 will take care of that for us.
Building Our EC2 Image
One of the first things we need to do is to create a new EC2 image (called an AMI) that contains all of the software needed to create our video conversion service. Because this process is quite detailed and time-consuming (and because this article is already pretty darn long) we are going to cheat. I have already done all of the configuration necessary to build our conversion service and turned it into a publicly accessible AMI that anyone can access. So, we are going to skip over most of the nitty-gritty details of installing software, etc. If you really want to go through that, there are more detailed notes with the public AMI. (See the related documents below for a link to the public AMI.)
Building Our Conversion Service
Based on the architecture shown in the diagram above, the basic steps required in our conversion service are:
- Read a message from our input queue
- Based on the data in the message, retrieve the input file from Amazon S3 and store it locally in our EC2 instance
- Perform our video conversion processing, producing one or more output files
- Store the generated output files in Amazon S3
- Write a message to our output queue describing the work we just performed
- Delete the input message from the input queue
The boto library provides a framework for this type of service in a class called, appropriately enough, Service. The Service class takes care of all of the details of reading messages, retrieving and storing files in Amazon S3, writing messages, etc. It also handles many of the common types of errors that come up when dealing with distributed services. For details on the Service class, you can view the source code here. For this article, though, we are just going to leverage that class and focus our efforts on what we need to do to get our video conversion service up and running.
To keep things simple, I've also already created a subclass of the Service class in boto to perform the video conversion. It's call ConvertVideo and the source code is shown below. This class is also part of boto and can be found here.
from boto.services.service import Service import os class ConvertVideo(Service): ProcessingTime = 30 Command = """ffmpeg -y -i %s -f mov -r 29.97 -b 1200kb -mbd 2 -flags \ +4mv+trell -aic 2 -cmp 2 -subcmp 2 -ar 48000 -ab 192 -s 320x240 \ -vcodec mpeg4 -acodec aac %s""" def process_file(self, in_file_name, msg): out_file_name = os.path.join(self.working_dir, 'out.mov') command = self.Command % (in_file_name, out_file_name) os.system(command) return [(out_file_name, 'video/quicktime')]
Our ConvertVideo class subclasses the boto Service class. That means we can leverage all of the Service class code to handle messaging, etc. The only thing we need to do is define how the video conversion process works. We do that by overriding the process_file method of the Service class. This is the method that gets called within the Service framework when there is an input file that needs to be processed. The process_file method takes two arguments:
- in_file_name - the fully qualified path to the input file to be processed. In our case, this will be an AVI format video file.
- msg - the message read from the input queue representing the work to be done. Right now, we can ignore this message because we are always performing the same conversion.
There are also a couple of class variables defined:
- ProcessingTime - defines the maximum amount of time we think it will take to process a file. This time is important because when we read an input message from SQS, we need to tell SQS how long to keep this message invisible from other readers of the queue. This is called the InvisibilityTimeout. If the timeout is too short, other services reading from the same queue might read the same message we are reading and perform the conversion again. Because the services are idempotent, this won't cause any harm but is a waste of computing resources. If the timeout is too long, the message could remain invisible longer than necessary if the original service that reads the message fails to process the message successfully. Eventually, the message will become visible in the queue again and will be read by another service but to provide reasonable response times, we don't want the timeout to be longer than necessary.
- Command - this is our command line for the call to ffmpeg to perform the conversion. The input file name and output file name have been parameterized so we can supply them at runtime.
The process_file method constructs the correct command line to run and then executes that command line using the os.system call in Python. The boto Service class expects the process_file method to return a list of tuples. Each tuple represents one output file generated by the service. The first element of the tuple is the fully qualified path to the output file and the second element of the tuple is the mime type of the output file. Since our simple service produces only a single output file (the MPEG4 file) we return a list with a single tuple.
Get the Message?
We have described how we are using SQS to help us scale our services and we have talked about the boto Service class handling the reading and writing of messages for us. But what do those messages actually look like? Here's an example input message for our ConvertVideo service.
Bucket: garnaat_fileit
InputKey: f84e4a20b571abc69baf2277d193e596
Date: Tue, 20 Feb 2007 17:21:21 GMT
OriginalFileName: MVI_3113.AVI
Size: 1126472
The basic message structure is very simple and should look familiar. It basically follows the same RFC-822 format used in mail messages and in HTTP headers. The required fields are described below:
- Bucket - the Amazon S3 bucket that contains input files and will be used to contain output files
- InputKey - the key of the input file in Amazon S3. The combination of the bucket and key provides a fully qualified reference to the input document. The boto service framework uses the MD5 hash of the file as it's key in Amazon S3. This is one of the ways we can guarantee that services are idempotent.
- Date - the date and time that the input file was originally stored in Amazon S3
- OriginalFileName - the original name of the input file
- Size - the size in bytes of the input file
Once our ConvertVideo service has completed processing a particular input message, it writes a message to the status queue describing the work that it just completed. That output message is shown below.
Bucket: garnaat_fileit
InputKey: f84e4a20b571abc69baf2277d193e596
Date: Tue, 20 Feb 2007 17:21:21 GMT
OriginalFileName: MVI_3113.AVI
Size: 1126472
OutputKey: e69e376be5af6f88f81d3e31adf27988;type=video/quicktime
Server: ConvertVideo
Host: domU-12-31-34-00-02-82
Service-Read: Wed, 21 Feb 2007 01:28:14 GMT
Service-Write: Wed, 21 Feb 2007 01:28:27 GMT
As you can see, this status message contains all of the fields from the original input message plus some additional fields added by the service, described below.
- OutputKey - the Amazon S3 key and mime type of the outputs of the service. This field could contain multiple entries, separated by commas.
- Server - the name of the service that processed this message.
- Host - the DNS name of the EC2 instance that performed the actual conversion
- Service-Read - the date and time that the service read the input message
- Service-Write - the date and time that the service wrote the status message
In a production environment, these output messages would be read from the output queue and persisted in log files or a database.
Enough Muck! Let's Convert Some Video!
First of all, if you are still with me; Congratulations! We are almost ready to put our service into action. As I mentioned earlier, I've already bundled the conversion service into a publicly available AMI (see the links at the end of this article). In addition to installing the necessary software to perform the video conversion, I also needed to modify the rc.local file in that instance so that it would automatically start up our conversion service as soon as the instance boots up.
But wait! How does our instance know what service to start up? Or where to read messages from? Or who's AWS credentials to use? Well, that's where instance user data comes in. A relatively new feature added to EC2 allows us to to pass arbitrary data to an instance when we launch it. This provides a great way to create very general purpose images with little or no hardcoded data. The boto Service class takes advantage of the instance user data feature in EC2 to allow a variety of parameters to be passed to the service at instance creation time.
Making it Work
Okay, now we are finally ready to use our super-scalable video conversion service. The first thing we need to do is submit some video files to be converted. We could provide a simple web upload page to submit the files but for now, we want to be able to get a bunch of files up there as efficiently as possible so we will use a command-line utility provided in the boto library. Let's assume that we have a bunch of AVI format video files sitting in a directory called movies in our home directory. Here's how we would submit those files to the video conversion service.
$ cd ~/boto
$ boto/services/submit_files.py -b myvideos -q vc-input ~/movies
50 files successfully submitted.
This command does a lot of work behind the scenes. Let's step through it. The -b option is used to specify the Amazon S3 bucket in which to store the input video files. The -q option specifies the SQS queue that will be used as the input queue for our service. The final argument is either a fully qualified path to a single file to submit to our service or a fully qualified path to a directory. If we pass a directory to the submit_files command will submit all files in the directory.
For each file processed by the submit_files command the file will be stored in the specified bucket in Amazon S3 using the file's MD5 hash as it's key in Amazon S3. In addition, for each file stored a message will be written to the specified queue. This message represents the work that needs to be performed on the file. In our case, that means the video conversion.
Now that we have stored our original video files in Amazon S3 and created messages in our video conversion service's input queue we can fire up our conversion service. Again, we will leverage a command-line utility in boto to make this as easy as possible. Remember, previously in this article we went through the steps to create and register our video conversion service's AMI in EC2 so all we need to do is create one or more instances of our service to process the messages in the input queue. To start with, let's just create a single service instance to process our files.
$ cd ~/boto
$ boto/services/start_service.py -r -m boto.services.convertvideo \
-c ConvertVideo -a ami-2eba5f47 -i vc-input -o vc-output \
-e firstname.lastname@example.com
Again, there's a lot happening here behind the scenes. First let's go through the arguments passed to the command.
- -r: this option means that we are starting a remote service. This same script is used to start up the service on the remote EC2 instance so this option is needed to tell the command whether it should be firing up an EC2 instance (as in our case) or starting the service software on the EC2 instance.
- -m: this option is used to specify the python module that contains our server class. The ConvertVideo class we created earlier resides in the module boto.services.convertvideo. You can create your services in any module you like, as long as you have configured your EC2 server instance so it can access the module.
- -c: this option specifies the name of our Python server class. We called our class ConvertVideo.
- -a: this option specifies the EC2 AMI id for our service. This is the value returned when you register the image with EC2.
- -i: this option specifies the name of the SQS queue that will be read for input messages for our service. This should match the name given when we called submit_files.py.
- -o: this option specifies the name of the SQS queue that will be used to store status messages for our service.
- -e: this option is used to provide an e-mail address that will be notified when a service is started or stopped. This just provides an easy way to tell when your service has been instantiated and is ready to start processing input messages and also when it has completed all processing and is shutting down.
- Process all of the command line arguments and construct a string that will be passed to the instances as UserData. This UserData contains everything the instance will need when it starts up.
- Start up a new instance of the AMI specified on the command line
- Once the new instances starts up, it will read the UserData passed to it
- Based on the UserData, it will load the appropriate Python class representing our service and create a new instance of that class. If the -e option was used on the command line the service will send an e-mail indicating that the service has started.
- The new instance of our service class will begin reading messages from the input queue specified in the UserData and will process the messages until the queue is empty
- The service will then terminate the EC2 instance in which it is running. Before doing so, if the -e option was used on the command line starting the service the service will send an e-mail indicating that the service is shutting down.
Once the service has completed it's work, we can grab the results. Here again we will leverage a command-line utility provided in boto to simplify this task.
python boto/services/get_results.py -q vc-status ~/movies
retrieving file: MVI_3110.mov
50 results successfully retrieved.
Minimum Processing Time: 2
Maximum Processing Time: 58
Average Processing Time: 17.820000
Elapsed Time: 896
Throughput: 3.348214 transactions / minute
This shows the kind of throughput we can expect from a single instance of our conversion service. But how about that scalability we talked about earlier? Well, let's make things a little more interesting. In our next test we will queue up 500 videos for conversion. Since we queued up 10 times more work let's create 10 times more servers and see how things go.
$ python boto/services/start_service.py -m boto.services.convertvideo \
-c ConvertVideo -r -a ami-2eba5f47 -e email@example.com\
-i vidconv-input -o test-status -n 10
Server: boto.services.convertvideo.ConvertVideo - ami-2eba5f47 (Started)
Reservation r-b4bf5bdd contains the following instances:
Now we will have 10 video conversion servers all reading messages from the same queue and processing the same set of work. In theory, that means the elapsed time to complete all of this processing should be about the same as it took a single server to process 50 files. Let's check on the results.
$ python boto/services/get_results.py -q test-status ~/movies
retrieving file: MVI_3110.mov
500 results successfully retrieved.
Minimum Processing Time: 2
Maximum Processing Time: 60
Average Processing Time: 17.794000
Elapsed Time: 928
Throughput: 32.327586 transactions / minute
Sure enough, the average processing time and elapsed time are almost exactly the same but our overall throughput is roughly 10 times higher than in our previous example which is exactly the sort of behavior we would expect and hope for.
Check Please!
We've created a framework for providing scalable services and shown some examples of how that framework can be easily be ramped up to handle increasing demands. We've also shown that our approach scales in a very linear and predictable manner, exactly what we want to see. One important question remaining, however, is " How much does it cost?". We can answer that question pretty easily because the get_results.py command, in addition to retrieving and summarizing the results found in a status queue, also creates a CSV file called log.csv in the directory specified on the command line. By bringing that file into a spreadsheet program like Excel (or by loading it into a database) we can get all kinds of stats about our services. Let's use that information to total up our bill for converting the 500 videos.
|2.5 GBytes
|2.5 GBytes
|Compute Resources
|8 Instances for ~ 20 minutes
A total of about $1.78 for converting 500 videos means a per/video cost of less than $0.004. Pretty impressive. And, unlike traditional computing infrastructure that is a fixed cost no matter what your actual demand looks like, this infrastructure cost can track your demand exactly.
Wrapping It Up
We've covered a lot of ground in this article. We've discussed the different Amazon Web Services involved, described a high-level architecture for combining those services into a scalable services framework and shown the performance and cost metrics of a video conversion service built with that architecture.
But that's really only the beginning. There's a lot more we could do to make this services framework even more useful, such as:
- Provide a browser interface for submitting videos for conversion. This would have to accept the POST'ed file submissions (and parameters) and then transfer the file to Amazon S3 and queue up a message to describe the work to be performed.
- Extend the video conversion service itself to handle a wider range of input formats and conversions. The ffmpeg program is very powerful and we should take better advantage of it.
- Load the status messages into a database so we can query about previous jobs and better track our service usage.
- Come up with a strategy for dynamically managing the EC2 instances rather than starting them up manually.
- Develop service support code in different languages. This article focused on my favorite language, Python, but since the main interface between consumers and producers in our architecture is via RFC822-style message headers we could easily write services in any language and have them interoperate.
- Lots, lots, more...
So get out there and produce your own scalable, reliable web services! AWS makes it easy.
Additional Resources
- Amazon Web Services: http://aws.amazon.com
- Amazon S3: http://aws.amazon.com/s3
- Amazon SQS: http://aws.amazon.com/sqs
- Amazon EC2: http://aws.amazon.com/ec2
- boto: http://code.google.com/p/boto/ (also listed in the Resource Center; see below)
- Python: http://www.python.org
- The Monster Muck Mashup public AMI (see below)
Mitch Garnaat is an independent software consultant living in Upstate New York. He has been designing and developing software for 20 years. For the past year, his focus has been on leveraging Amazon Web Services. He is the author of the open source boto library which provides a Python interface for an expanding set of Amazon Web Services and has been developing AWS-based applications for a variety of customers.


text:
FUNDRAISERS will be stepping out in their animal onesies for a sponsored walk at Dudley Zoo.
The wander around the zoo's 40 acre site on Saturday (May 3) will coincide with Get Walking Week and help save one of the world's rarest big cats.
Walkers will also be able to see their favourite species en-route during the 2km, 5km or 10km treks.
Proceeds will be split between the zoo's conservation projects and 21st Century Tiger, a charity that supports tigers in the wild.
The zoo's marketing assistant, Andrea Hales, said: "Not only will you be discovering the pleasures of walking and its health benefits, but you'll also be raising money towards critically endangered Sumatran tigers in the wild, where there are now less than 140 existing.
"Staff have been practising for the walk over the last few weeks by wearing their onesies while carrying out their daily duties.
"We're all really looking forward to it, so we hope many of you will join us and help us do all we can to ensure the survival of Sumatrans."
To register, visit www.dudleyzoo.org.uk or call 0844 4742272.


text:
Paullinia Cupana for Anorexia in Oncologic Patients
Recruitment status was: Recruiting
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
|Cancer-related Problem/Condition Anorexia Loss of Weight
|Drug: Paullinia cupana
|Phase 1 Phase 2
|Study Type:
|Study Design:
|Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
|Official Title:
|Guarana (Paullinia Cupana) for Anorexia Related to Cancer
- weight [ Time Frame: eight weeks ]Patients will considered to respond to guaraná if the gain 5% or more of his inicial weight during the treatment period
- quality of life [ Time Frame: eight weeks ]Weekly patients will answer questionaries about quality of life like FACT-G
|Estimated Enrollment:
|Study Start Date:
|April 2011
|Estimated Study Completion Date:
|July 2013
|Estimated Primary Completion Date:
|July 2013 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: Paullinea cupana
50mg of Paullinia cupana as capsule, twice daily
Drug: Paullinia cupana
50mg of Paullinia cupana as capsule, twice daily
Detailed Description:
Patients 18 years and older, diagnosed with any cancer, that is losing weight and have anorexia will be selected. They must have normal levels of creatinine, thyroid evaluation and hepatic function. If they are taking corticosteroid, they must keep losing weight and refer anorexia, as well as if they are on treatment with chemotherapy.
Patients will receive 50mg of the guaraná twice daily for 4 weeks. Every week will be an evaluation of the weight, level of appetite and answer 2 questionaries of quality of life and level of symptoms (FACT-G and MDASI).
This is a fase II study, open-label, no randomized, with two steps following ¨two stages of Simon¨ model. First step 18 patients will be included and if there are 3 good responses second step will follow, including 17 more patients. Response will be considered if there is at least 5% of gain in the weight.
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- adults (18 years old and older)
- palliative care or oncologic treatment
- loss of weight
- anorexia
Exclusion Criteria:
- gastrointestinal obstruction
- blood pressure not controlled
- diabetes not treated
Please refer to this study by its ClinicalTrials.gov identifier: NCT01540019
|Faculdade de Medicina do ABC
|Santo André, São Paulo, Brazil, 09060-650
|Contact: Claudia Latorre 55117717-3241 firstname.lastname@example.com
|Study Chair:
|Claudia Latorre
|Faculdade de Medicina do ABC
|Responsible Party:
|Felipe Melo Cruz, MsC, Faculdade de Medicina do ABC
|ClinicalTrials.gov Identifier:
|NCT01540019 History of Changes
|Other Study ID Numbers:
|Study First Received:
|January 29, 2012
|Last Updated:
|February 22, 2012
Keywords provided by Felipe Melo Cruz, Faculdade de Medicina do ABC:
Paullinia cupana
loss of weight
Additional relevant MeSH terms:
Weight Loss
Signs and Symptoms, Digestive
Signs and Symptoms
Body Weight Changes
Body Weight
ClinicalTrials.gov processed this record on September 21, 2017


text:
Participate – for the sake of art
Last weekend, my wife and I enjoyed touring several of the San Francisco Museum of Modern Art's "Project Los Altos" exhibits.
We found the most interesting part in the back room of 359 State St., exploring the exhibit "Everything Is Perfect." We talked at length with charming Czech artist Katerina Šedá. She is becoming widely known on both sides of the Atlantic for her installation art – she has done work at the Berlin Biennale, the Tate Modern, the University of Chicago and numerous other sites. She has brought to Los Altos a similar social artwork.
Her exhibit is a web-based framework in the form of a contest that challenges Los Altos residents to write what makes them exceptional.
Everyone is best at something – what is it? She creates a game that may be comfortable for children but can be a challenge for competitive adults. And what a great challenge it is to come up with something humorous and out of the ordinary! (One child claims to have the largest collection of roly-polys.)
Šedá asks us to share that uniqueness with others and complete the project by submitting a listing. The final artwork is created by residents, but only if we participate.
Mike McCusker
Los Altos
Spotlighting another 'Festival of Lights'
Put down that turkey leg! Stop checking that list! The Lively Foundation's "Festival of Lights" is here to remind you of the reasons for the season.
Lively's "Festival of Lights" is a concert featuring songs, dances, theater and storytelling, all related to light in many holidays at the end of the calendar year.
After 15 years of applause from a dedicated following in San Francisco, The Lively Foundation will brighten the mid-Peninsula with the "Festival of Lights" 3 p.m. Dec. 8 at the Mountain View Masonic Center, 890 Church St.
Guest artists include elves, ribbon dancers, a dragon, Jonathan Clark on bass and dancers Julia Canavese, Amity Johnson, Vanessa Nudd and Etta Walton. I am the production's choreographer and writer.
Forget about searching for parking – there is a lot of free parking around the Masonic Center and its own lot right behind the building – just let your little light shine. The "Festival of Lights" will renew your personal energy source.
Tickets are $12 general admission, $10 over age 65 or under 10.
For tickets and more information, visit livelyfoundation.org
Leslie Friedman Artistic director
The Lively Foundation
Mountain View
'Master Tech' offers valuable advice
One of my favorite Town Crier features is "Ask the Master Tech." Warren McCord's pragmatic advice is very useful to all drivers. We are indeed fortunate to benefit from his expertise.
I never miss reading his column, and I remind family members to do likewise.
Judy Fimmel
Los Altos Hills
'Prime Time Dads' available at Linden Tree Books
Thank you for that wonderful article on Len Filppu's appearance at Linden Tree Books to discuss his book "Prime Time Dads: 45 Reasons to Embrace Midlife Fatherhood" ("Author touts joys, advantages of 'prime time' fatherhood," Nov. 20).
Our only wish is that you could have mentioned that "Prime Time Dads" is available at our lovely brick-and-mortar independent bookstore!
Los Altos Town Crier readers can buy and order books at Linden Tree rather than going online to help keep a great children's independent bookstore in Los Altos.
Dee Ellmann
Linden Tree Books
Los Altos


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Miguel and Kacey Musgraves Get Close in 'Waves' Video TeaseThe video finds Miguel getting very up close and personal with the country star.
26 Delicious Songs You Can Bring on a Picnic, from A to ZFrom A to Z, we list out the tastiest songs to bring with you to each and every picnic you attend this summer.
6 Artists Katy Perry Should Enlist For Her Super Bowl Halftime ShowFrom a Material Girl to an old flame to a Neon Icon, we came up with six artists that we'd like to see join Katy during halftime.
One Direction's Harry Styles Very Much Enjoys Kacey Musgraves' MusicEarlier today (Sept. 16), Harry Styles took to Twitter to share his current guilty pleasure. Turns out he's a pretty big fan of Musgraves.
Katy Perry & Kacey Musgraves Collaborated on a 'Wizard of Oz'-Themed SongTheir collaborative song is inspired by the beloved childhood film.
Katy Perry & Kacey Musgraves To Team Up For 'CMT Crossroads'The California Gurl is going country.
Behind the Scenes at the 2014 GRAMMYS with Macklemore & Ryan Lewis, Daft Punk, Kacey Musgraves & MoreWhat goes on behind the scenes at the GRAMMYs? Hear what winners such as Macklemore & Ryan Lewis, Nile Rodgers, Kacey Musgraves, Darius Rucker & more had to say, and find out which artist brought the press room to tears.
2014 GRAMMY Performances, RankedThis year it seemed like the words "And the GRAMMY goes too" were hardly uttered during the night's live broadcast, leaving plenty of room for the performances, which there were 20 of. All of which we ranked.
GRAMMY Red Carpet 2014: Best and Worst DressedKudos to Kacey Musgraves & Taylor Swift; what were you thinkings to Macklemore, Ryan Lewis & Pharrell's hat.
MusiCares Tribute To Carole King Spans Generations, GenresSteven Tyler, P!nk, Lady Gaga, Sara Bareilles, Zac Brown, Miranda Lambert, Miguel and Alicia Keys were among the many artists who paid tribute last night to one of the greatest songwriters of popular music.
Behind the Song: Kacey Musgraves' 'Merry Go 'Round'"When we were about to pick the first single I really lobbied for 'Merry Go 'Round' because I'm out there every night and I can tell you, hands down this is the one people are connecting with. I'm really glad that was my first thing to say to the world."
Taylor Swift, Macklemore & Ryan Lewis and More to Perform at 2014 GRAMMY AwardsThe show will also see a reunion of the remaining Beatles, Paul McCartney and Ringo Star.


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PENSIONERS may be moving in as officers move out if a scheme to turn a local police station into retirement apartments goes ahead.
Developer McCarthy and Stone has unveiled plans to create 37 apartments at Bridgwater police station, Northgate, once Avon and Somerset Police move to new premises being built at the Express Park outside Bridgwater.
The developer intends to submit a planning application in March.
A public consultation was held on Wednesday at Bridgwater Arts Centre where McCarthy and Stone displayed their plans and talked to potential apartment owners.
Charles Creed from The Planning Bureau, lead architect on the project, said: "It's close to the town centre and on a very good bus route.
"For that reason some of the people are from slightly further afield and want to move here. One lady who came was from Cornwall.
"One thing we take quite seriously is talking to local people and local authorities in advance. So far people have been quite receptive."
Mr Creed is keen that the proposed apartments fit in with the local architecture.
"It's about enlivening and putting an active frontage on the street where currently one doesn't exist."
Brian Smedley, councillor for Westover Ward, said people in the area were generally receptive to the plans. He said: "The only concern I received from neighbours and residents in the area was will there be enough parking spaces. Home Castle House is a similar building at it has 32 residents and only six parking spaces."
A spokesperson from McCarthy and Stone confirmed that there will be 27 parking spaces for the new apartments.


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Did You Know?
Amur Tigers are the biggest cats in the wild, topping out around 600 pounds!
This week is National Veterinary Technician Week. Veterinary Technicians are a very integral part of the veterinary medical team, as well as part of the zoo. In fact, without a veterinary technician (or zookeepers) I pretty much could not do my job, or at least do it well.
What are veterinary technicians? They are the equivalent of a nurse in human medicine. Technicians are the organizers, the laboratory testers, the prescription fillers, the surgical assistants, and in general they help with every aspect of veterinary medicine. Veterinary technicians are well trained individuals who have gone through a 2-4 year degree program to learn various aspects of veterinary medicine including placing IV catheters, cleaning and polishing teeth, identifying parasites, performing blood counts, identifying cells from masses or other organs, monitoring anesthesia and how to assist in surgeries. In fact, veterinary technicians are so involved in all aspects of veterinary medicine they are and should be the right hand of any good veterinarian. In private practices veterinary technicians are typically the ones who you see when you bring your pet in and they perform the initial evaluation of your pet, they may be the practice manager, or they may be in charge of organizing and keeping all surgeries going smoothly.
Here at the zoo we have a veterinary technician, Debbie, who also helps keep everything going. Specifically she assists in every medical procedure we perform here at the zoo, which is well over 800 procedures per year! She identifies any parasites the animals may have, reads blood smears from our birds and reptiles, and sets up and cleans up for any surgeries that we perform here at the zoo. That is quite a bit for one person! In addition to all of that she also helps to take care of any new animals who arrive to the zoo including feeding them and keeping their enclosures clean. Now I am not discounting any of our other staff here at the zoo, I am pretty dependant on many of our other staff as well, but our technician helps keep me organized and focused on following through with all of the routine animal care required (vaccines, and physical exams) as well as all of the unexpected sick animal treatments and care. So to veterinary technicians everywhere, thank you for what you do for veterinary medicine and keep up the good work! We couldn't exist without you!


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BP Comment Quick Links
|Strength of Schedule Report
December 1, 2011
BP Podcast
Episode 74: You're Off To A Bad Start
It's a short show, because we wanted to get to all of your great email. Still, we yammer for about an hour about a variety of subjects, have a quick That Just Happened and tell you of our plans for three shows next week in Dallas. As always, we hope you enjoy.
Note: We do alert you to the presence of the occasional adult language and subject matter. Don't say we didn't warn you.
Up And In Episode 74: "You're Off To A Bad Start"
Download Here (52.5 MB; 57:24)
Contact Information
Email Us: email@example.com
Table Of Contents
0:00 Breaker! This is Country Mouse
1:42 Housekeeping
2:12 Emails!
- Why aren't contracts front-loaded
- Why some tools guys are just tools guys
- Converting position players to pitchers
- The potential of having a scout on the show
- Josh Leuke and the philosophy of redemption
- Getting a job doing what we do
- The use of the term 'sexy' to describe prospects
- Guilty pleasures
- Being in one band, one place, one time
- Taking the show into the bedroom
48:29 Impromptu That Just Happened
51:13 Plans for Dallas
Music is by Snailface, all rights reserved, courtesy of the artist.
Kevin Goldstein is an author of Baseball Prospectus.
8 comments have been left for this article.
BP Comment Quick Links
So next week's shows will be the best because they are being recorded in Texas?
Dec 02, 2011 05:36 AM
The "sexy" discussion had me audibly laughing on the bus this morning ... well done!
Dec 02, 2011 07:25 AM
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text:
The live video feed of the Dalai Lama's San Diego speeches has concluded.
View the photo gallery: Dalai Lama at USD
View the photo gallery: Dalai Lama at UCSD
View the photo gallery: The Dalai Lama arrives
The Dalai Lama in San Diego
Tickets to the Dalai Lama's sole public event Thursday at SDSU is sold out but his talk can be viewed at dalailamasandiego.org/watch_live.php.
Thursday 9:30 a.m.: The Dalai Lama will address "Upholding Universal Ethics and Compassion in Challenging Times" in San Diego State University's Viejas Arena. The talk also can be seen at sdsu.edu. No general on-campus parking or in surrounding area without a permit. Campus officials advise taking public transit. More information..
The Dalai Lama's Twitter feed is @DalaiLama and his Facebook page is facebook.com/DalaiLama
The Dalai Lama wears many hats
Some wanted more from Dalai Lama
Dalai Lama dilemma: Whatever to eat?
Heading to higher ground at USD
Faith and reason: the Dalai Lama at UC San Diego
Dalai Lama gets mixed reviews at UCSD
Early risers gather for Dalai Lama
Dalai Lama arrives to rock star greeting
Dalai Lama trivia: Did you know?
Dalai Lama here today - and why we careCopyright © 2017, The San Diego Union-Tribune


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Mike Krzyzewski announced he was returning to coach Team USA for the 2016 Olympics. That was all it took for Chris Paul to decide against sitting out.
According to ESPN.com's Jeff Goodman, the Los Angeles Clippers guard is leaning toward playing for Team USA in Brazil as he goes for his third gold medal with the team on the international level.
"If it had been another coach than Coach K, I was prepared to be done," Paul told ESPN.com.
Despite a strong group of young players like Derrick Rose, Kyrie Irving, Russell Westbrook and Stephen Curry, Paul, who will be 31 when the Olympics come around, figures to be a big piece.
If Paul does elect to play, he would join Thunder star Kevin Durant and Timberwolves center Kevin Love. They both committed last week to playing in 2016.


text:
Posted 5 years ago
(136 items)
This is a Presidential Profile of President John F. Kennedy, from 1966. It is narrated by Art Baker and in pretty good condition.
It's numbered #35, I would assume that they came out with one for every president. It appears to have been put out by the First Federal Savings & Loan Association of Oakland (MI).
Whenever I find Kennedy related items, I snatch 'em up.
Thanks For Looking!!


text:
McSweeney's Issue 36
McSweeney's Publishing, San Francisco, California, 2010
Project brief: All McSweeney's books and journals are edited and designed by the eight-person staff of McSweeney's Publishing in San Francisco, CA. Our goal, every time we design a book, is to inspire very busy strangers to notice the book, pick up the book, read the book, and enjoy the reading experience.
McSweeney's Quarterly Concern is our flagship publication, and we aim to rethink the design with every issue. Making an issue in the form of a cube-shaped, life-size human head felt viscerally right. The format seemed like it could be fun, memorable, and even motivating for all the writers and artists involved.
Approach: It seemed important to have a lot of air in the box. We wanted enough empty space inside the head so that readers could really dig in with both hands and sift around. But even with all the airspace, we packed something like 600 pages of material in here, plus a forty-inch scroll of fortune-cookie fortunes and four postcards. With the possible exception of the broadsheet newspaper issue we did in 2009 (McSweeney's #33 — the San Francisco Panorama), the head box is, by a long shot, the issue with the most writing and artwork in it.
We liked the idea that readers might feel the urge to stick foreign objects into the head — like a toy, or another book, or a can of Vienna sausages. The issue's introduction invited readers to send in pictures of themselves holding the head, and we were blown away by the hundreds of amazing shots our readers took the time to shoot and send in. It felt great to connect with readers like that over a ruddy, sweaty mustachioed head.
Here's how the issue is described on our store website: "Inside this 275-cubic-inch full-color head-crate, there are all the things you'd hope for: a 100-page annotated fragment of Michael Chabon's lost novel, incredible new stories from John Brandon and Colm Tóibín, Jack Pendarvis's "Jungle Geronimo in Gay Paree," a play by Wajahat Ali - eight astounding booklets in all, along with some other things on top, enough for hundreds and hundreds of pages of perusal, every bit of it, like we said, contained in a more-or-less life-size, friendly-looking head. It will fit on your shelf, it is compatible with most hats, and the stuff inside is wonderful."
Effectiveness: When the first heads came back from the printer without any unforeseen structural problems or glaring errors, we felt instantly relieved. A few days after the issue shipped out to subscribers, we had fun pausing to think pointless thoughts like, "At this very moment, the U.S. Postal Service is placing hundreds of disembodied heads on doorsteps around the country. And it's because of us." In an Amazon.com reader review, someone began their review like so: "Where to begin? I've never received a more surprising object in the mail." That was a satisfying comment to read.
Juror Notes
Just plain fun. There's simply no way you wouldn't show this to anyone who likes books.
- Design firm
- McSweeney's Publishing
- Art director
- Brian McMullen
- Designer
- Brian McMullen
- Illustrators
- Jules de Balincourt, Sophia Cara Frydman, Matt Furie, Ian Huebert, Daniel Krall, Leon Krier, Michael Kupperman


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The Craven, Aire & Wharfe Junior League have received the Charter Standard League of the Year 2012 award from the West Riding County Football Association.
The award was presented at Valley Parade to the league's management committee by Hannah Simpson, chief executive officer of the West Riding County FA.
The recognition follows the extension of the age range to include mini-soccer (seven years to ten years), the introduction of the new nine verses nine standard for under-11s and under-12s and the achievement in becoming a Charter Standard League.
The range of activities provided to support the development of member clubs was also a major part.
Member clubs and individuals connected with the league were also honoured, such as George Brown (Oakworth Juniors) for Football Futures, and Marcus Strudwick (Idle Juniors) and Lee Maran, who are members of the West Riding County FA's management team. Maran was also recognised as Young Volunteer of the Year.
Meanwhile, Fairbank United received the Charter Standard Club Award and Salts Juniors the Charter Standard Development Club Award.
The league, which started in 1981 with just six teams, now includes 50 member clubs and 337 teams and extends from Grassington and Settle to Bradford and Otley.
There was also a recent nine verses nine event at Marley involving juniors from Campion and Wilsden.
It was run by Andy Foster, regional coach development officer from Sheffield, who gave a coaching demonstration for managers.
Afterwards six teams took part in a small tournament using the all-weather pitch.
The league have also run two evening sessions for club referees with the aim of helping them im-prove their own performance, while an IT support session has been held at Phoenix Service Solutions in Keighley.
The object there was to help club officials use the internet for registering players and submitting match results.


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JASON GILLESPIE believes panic has cost Yorkshire four points in NatWest T20 Blast cricket during the last week.
The Vikings head into tonight's clash with North Division co-leaders Worcestershire Rapids at New Road in danger of their campaign unravelling when they should have been on course for the quarter-finals.
Although there is still time to turn it around, Yorkshire could, and should, have been sitting at the top of the table with 14 points from nine matches instead of being in mid-table with only ten on the board.
In their last three fixtures, they have failed to chase down 144 against Nottinghamshire at Trent Bridge on Saturday and just 124 against Durham at Headingley on Wednesday.
The latter chase was one which coach Gillespie described as "99 times out of 100 you should never lose".
"Regardless of the situation, we always go out and try to be positive with the bat," said Gillespie.
"Whether we are chasing 50 or 200, our goal is to be very positive.
"I'm a firm believer that you get into the best batting positions by looking to score runs and being very positive and playing your natural game as much as possible.
"I don't think that complacency has come in, I genuinely think that the pressure was on and there was a bit of panic and we just didn't adapt to that."
Added the Yorkshire coach: "Durham bowled well with the change-up bowlers on. (Paul) Collingwood is only medium pace, but he is canny, running his fingers over the ball.
"We've had two bowlers do that to us in the last few games in Mullaney and Collingwood. At important moments, there is almost a bit of panic.
"We're making it difficult for ourselves without question, but we'll be up for the challenge. Worcester have played some good cricket, but they are by no means unbeatable.
"We'll go there with a real positive frame of mind and have a go."
Yorkshire's two aforementioned performances with the bat were all the more frustrating given their fielding and bowling against Notts, Leicestershire, a game which they did win, and Durham was exceptional.
"It shows that in T20 cricket, you can't just rely on one part or two parts of the game," added Gillespie.
"You need to make sure you're across all the disciplines, and you're absolutely nailing your skills because if you don't, as we saw against Durham, you lose a game that 99 times out of 100 you should never lose.
"It is a mindset thing because it's not a skill issue. Our lads are going out there having prepared well, and are practicing well with the bat in hand and doing all the right things.
"They are practicing with a lot of purpose quite specific to what they are trying to achieve out in the middle. The key is transferring that to a match situation. We have no excuses, we just need to be better."
Yorkshire, who face a Worcester side who won six on the bounce prior to a washout last Friday, have named an unchanged squad.
Captain Andrew Gale is expected to play even though his wife was due to give birth to their second child yesterday.
Yorks 14-man squad v Worcester: Gale (capt), Bairstow, Bresnan, Finch, Hodd, Leaning, Lees, Lyth, Patterson, Pyrah, Rafiq, Rashid, Robinson, Sidebottom.


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Treatment Decision Impact of OncotypeDX™ in HR+, N- Breast Cancer Patients (SWITCH)
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Primary objective:
Determine the impact of the Oncotype DX Recurrence Score (RS) on the treatment recommendation made (administration of chemotherapy or not, in addition to hormonotherapy) in a HR+, N- or pN1(mi), Her2- breast cancer adjuvant population.
The impact of Oncotype DX on treatment recommendations can be either a decrease in treatment intensity defined as a change in treatment recommendation from chemotherapy plus hormonal therapy to hormonal therapy alone or an increase in treatment intensity defined as a movement from hormonal therapy alone to the addition of chemotherapy to hormonal therapy.
Patients with HR+, N- breast cancer currently represent around 70% of newly diagnosed breast cancers. These are usually good prognosis tumors. However, on the basis of classical clinical and pathological prognostic parameters and markers, the international consensus guidelines recommend treatment with hormone- and chemotherapy in 85-95% of the cases. Considering the natural disease history, such as documented by the EBCTCG meta-analysis, more than 50% of these patients are overtreated, which leads to unnecessary side effects and costs to the health system and to the society.
Oncotype DX appears to be well adapted to therapeutic de-escalation as it targets HR+, N- patients and is performed on fixed paraffin embedded tissue (FPET). It is therefore best adapted to daily clinical practice as it does not necessitate any specific surgical procedure or tissue freezing.
The prognostic and predictive value of Oncotype DX in ER+, N- patients has been validated on three large adjuvant randomized trials (NASBP B-14, NSABP B-20, and the ATAC study). The test has been commercially available in the USA since 2004, and is being used for more than 50% of the HR+ N- patients in this country.
While Oncotype DX has been validated in the USA, it needs to be independently evaluated in France, in the context of the local treatment guidelines and habits, to provide data that are meaningful to the French health system and to the French medical community.
|Breast Cancer
|Device: Oncotype DX breast cancer test
|Study Type:
|Study Design:
|Intervention Model: Single Group Assignment
Masking: None (Open Label)
|Official Title:
|Treatment Decision Impact of OncotypeDX™ in HR+, N- Breast Cancer Patients
- impact of the Oncotype DX Recurrence Score on the treatment recommendation made [ Time Frame: Day 15 ]The impact of Oncotype DX on treatment recommendations can be either a decrease in treatment intensity defined as a change in treatment recommendation from chemotherapy plus hormonal therapy to hormonal therapy alone or an increase in treatment intensity defined as a movement from hormonal therapy alone to the addition of chemotherapy to hormonal therapy.
- Level of confidence of the physicians relating to their treatment recommendation before and after Oncotype DX RS results [ Time Frame: Day 15 ]The change in physicians' level of confidence in the treatment recommendation will be measured by the change from baseline to follow-up responses.
- Physicians' perceptions regarding the utility of the Oncotype DX. [ Time Frame: Day 15 ]
|Study Start Date:
|January 2011
|Study Completion Date:
|May 2012
|Primary Completion Date:
|February 2012 (Final data collection date for primary outcome measure)
|Assigned Interventions
|a HR+, N- or pN1(mi), Her2- breast cancer adjuvant population
Device: Oncotype DX breast cancer test
The Oncotype DX breast cancer test measures the expression of 21 genes of an individual tumor to generate an Recurrence Score result that quantifies the magnitude of chemotherapy benefit and the likelihood of recurrence for early-stage breast cancer patients.
Other Name: Oncotype DX™
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Patients > 18 years old.
- Pre- or post- menopausal women with breast adenocarcinoma, confirmed by a pathologist and who underwent surgery, with a maximum of 4 weeks between surgery and the 2nd therapeutic decision with Oncotype DX.
- HR positive (at least ER+) breast cancer patients (defined by a threshold of 10% of the cells IHC + without N- or pN1(mi), Her2 - (IHC0, 1, 2+ or FISH -)
- Patients must be eligible to receive adjuvant chemotherapy as defined by a good Karnofsky index, no hematological, cardiological or hepatic contraindications nor any impeding comorbidity.
- Patients must have given a written informed consent.
Exclusion Criteria:
- T3 or T4, HR-, N+ (except pN1 (mi) (sn), Her2+ (IHC 3+ or Fish+) patients.
- Metastatic patients.
- Patients who cannot give an informed consent.
- Patients who cannot receive chemotherapy.
- Patient who participated in another clinical trial and is still in the exclusion period of any other trial.
- Mentally disabled patient who has no legal responsibility for herself.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01446185
|CHRU Besançon
|Besançon, France, 25030
|Centre Jean Perrin
|Clermont-Ferrand, France, 63011
|Centre Val d'Aurelle
|Montpellier, France, 34298
|Centre Azuréen de Cancérologie
|Mougins, France, 6250
|Centre d'Oncologie Médicale de Gentilly
|Nancy, France, 54000
|Hôpital TENON
|Paris, France, 75020
|Principal Investigator:
|Joseph GLIGOROV
|Hôpital TENON
|Responsible Party:
|Genomic Health®, Inc.
|ClinicalTrials.gov Identifier:
|NCT01446185 History of Changes
|Other Study ID Numbers:
2010-A00577-32 ( Other Identifier: AFSSAPS identification number )
|Study First Received:
|September 1, 2010
|Last Updated:
|April 17, 2013
Keywords provided by Genomic Health®, Inc.:
HR+, N- or pN1(mi), Her2- breast cancer adjuvant population
Early Breast cancer
Gene Expression
treatment options
Hormone receptor positive
Additional relevant MeSH terms:
Breast Neoplasms
Neoplasms by Site
Breast Diseases
Skin Diseases
ClinicalTrials.gov processed this record on September 21, 2017


text:
Steve wrote:Joz wrote:zj1002 wrote:keeping it? I got paypal
Haha. Man, two weeks ago I woulda said, "Sure!" But I picked up one the other week, and I have to say these things are amazing! Fits right in with my C-MD2. Great disc, wished I woulda discovered it earlier.
What weight did you get?
The one I got from PIAS is 178, the one I had just bought from fatbackbob is 180 (183 apparently on the scale). They're wonderful midranges...


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text: In nature, pentagonal symmetry is rare in inanimate forms. Packed soap bubbles seem to strive for it but never quite succeed, and there are no mineral crystals with true pentagonal structures. But pentagonal geometry is basic to many living things, from roses and forget-me-nots to sea urchins and starfish. [Robert Bringhurst, "The Elements of Typographic Style," 1992]


text:
Very, very sad. She's only 4 years old.
Artest is playing with heavy heart
His young daughter has a cancerous tumor on her kidney
By Sam Amick - email@example.com
Last Updated 6:01 am PST Monday, December 3, 2007
Story appeared in SPORTS section, Page C1
Print | E-Mail | Comments (0) | Digg it | del.icio.us
Ron Artest had ice on nearly every part of his body Sunday afternoon at Kings practice, from his shoulder to both knees and even a cold pack he wore on his hip.
But the bumps and bruises are nothing compared to the heartache Artest and his family have felt recently. In an exclusive interview with The Bee, the Kings small forward revealed that his 4-year-old daughter, Diamond, has a cancerous Wilms' tumor on her kidney.
The youngest of Artest's four children has already undergone surgery and a biopsy at the Peyton Manning Children's Hospital in Indianapolis, and she began chemotherapy on Thursday before heading home. The tumor will need to be shrunk by way of chemotherapy before doctors can consider whether to remove it. Normally, doctors would remove the cancerous tumor and kidney, but Diamond was born with just one kidney, Artest said.
"The good thing about it is there's a 90 percent chance survival rate," said Artest, who has made two trips to Indiana since Nov. 21 to be with his daughter and missed one game. "It's a curable cancer, so that's something to look forward to. She's getting chemo. She's a tough girl. She's not really complaining too much ... . My baby's precious. It's in God's hands."
Luckily, she complained a little. Diamond, who lives with Artest's wife, Kimsha, in Indiana, told her mother about stomach pains enough times that they headed for the hospital in mid-November.
"We'd give her Pepto-Bismol," Artest said. "But the last time she complained, we just took her in."
The doctors felt a lump in her stomach and performed tests, eventually discovering she had a Grade 3 Wilms' tumor.
"We got lucky (in discovering it), but I wish we would've caught it at (Grade) 1," Artest said. "It was tough on her. It was tough on everybody. Everybody loves Diamond. I couldn't talk about it at first. I just wanted to get more info from the doctors."
And, of course, from the Internet. Artest said he spent sleepless nights browsing Web sites learning about Wilms' tumors, which primarily affect children and are named after a 19th-century German surgeon who recognized that the cancer develops from immature kidney cells. The tumor strikes one in 10,000 children, according to the Institute of Cancer Research.
Artest said he learned about the survival rate, about how – according to the American Cancer Society – 92 percent of patients live at least five years beyond their time of diagnosis and how approximately 500 new cases arise in America each year.
Those who've met Diamond know she's as vibrant as her name suggests, a side of her that was on display during Las Vegas summer league in July. As Artest sat courtside watching his younger Kings teammates with all four of his children, a rambunctious Diamond drew a scold from Artest. In between fistfuls of popcorn, Diamond rolled her eyes like a mini diva and forced a smile from her relenting father. The sickness, Artest said, hasn't changed her spirit.
"It was tough; it still is tough," he said. "But she's tough enough to get through it. She'll say, 'I feel OK – why am I still (in the hospital)?' She doesn't understand. She's only 4 years old."
Basketball, Artest acknowledged, just doesn't seem as important. He'd rather stay by his daughter's side in Indiana, helping the family through this time while praying for progress. But after a season in which his off-court troubles marred an otherwise-strong showing in 2006-07, he was already behind this season because of the seven-game suspension that officially ended that chapter. What's more, he is in a contract year, able to opt out of his deal this summer and looking to rebuild his reputation on and off the floor.
"It's tough because this season is the second-most important thing right now," he said. "If everything (else) was OK, then the season would be the most important, as far as career and your profession ... . But right now, my daughter's first and my career's second."
He's fulfilled both duties recently, scoring at will for most of his eight games played while defending with the sort of ferocity that earned him the 2003-04 Defensive Player of the Year Award. And even with the extra burden of his family situation, the player known for staying after practice for extra work continues to log extra hours. Saturday, he was simply trying to catch up with his teammates, landing via commercial plane at 11:30 a.m. in Sacramento and heading straight to the team's shootaround for that night's game against Houston.
Kings coach Reggie Theus said the circumstances mean he'll continue to let Artest dictate his own schedule.
"I think he's got his priorities in line, but I think it's a tough job because he knows he's got to be there (in Indiana), and yet he's coming back and forth," Theus said. "We're sort of trying to get an idea of what his thinking is. As long as he has us on his mind in terms of what we need from him and he's trying to make it work, you just can't make this the priority. I appreciate it, and I know the team does."
Artest said he might look at arranging treatment for his daughter in Northern California and bringing her to Sacramento. But for now he'll monitor Diamond's chemotherapy treatments in Indiana with lots of phone calls and visits whenever she comes calling.
"A lot of guys asked me: 'Why are you back? Why are you playing?' " Artest said. "If my daughter needs me, then I'm leaving. If she's OK, then I'm going to come play."