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'There are 39 games gone, many of them wasted. With Ruff going with Miller and junking his goaltending rotation he said, "We're at a stage now where we have to start making a move. We're starting to get healthy, we just got Nathan back which was a plus for us. Getting Myers back should be a plus on the back end. We're still missing a couple of key pieces on the back end, but we've got to set course, we've got to win games. We're going to have to win some game where we don't play well in, but the goaltender steals it."'
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ORCHARD PARK, N.Y. — Buffalo Bills wide receiver Stevie Johnson lives by the motto, "handle business and have fun." The handle business refers to football—he must practice hard, prepare well, catch everything thrown to him and more important than all of that, help the Bills win. If all of that happens, he can cut loose.
At 5-2, the Bills are breaking out in a big way and Johnson is a big reason why. He has 39 catches for 439 yards and four touchdowns, so he and the Bills have handled business.
The have fun part? After hanging out with him and hearing stories about him—just this week, he dressed up as Bills coach Chan Gailey and posted a picture on Twitter with a quote he made up from Gailey—I'm confident the man could have fun at a librarian's convention.
Right now, he's at a Japanese steakhouse with his wife, Britney, their two small children and his cousin. Through the air toward him flies a piece of broccoli, flung off the chef's spatula. The point of this little bit of culinary charm is to catch the food in your mouth. Doink! Off Johnson's face. Here comes another one ... Doink! Off his face again. Here comes the third ... he snatches it.
The chef launches one toward Britney. She catches it on the first try. I point out that Stevie is the one who is supposed to catch everything, but he dropped two and got schooled by his wife. He laughs. It is perhaps the only time he has ever laughed about dropping anything. Catching is handling business. Dropping is not fun.
Johnson was watching highlights of Chad Ochocinco and Terrell Owens before the Bills played the Cincinnati Bengals in Week 11 last season. Someone on TV noted the two were calling themselves Batman and Robin, and Johnson decided he wanted to get in on the fun.
He found a marker, and on his T-shirt under his uniform he wrote, "Why so serious?" — a quote from the Joker in the most recent Batman movie. He grabbed quarterback Ryan Fitzpatrick and told him that if he scored a touchdown, he'd pull up his uniform and reveal the message.
This is spontaneous decision No. 1 that worked out well.
He scored (three times, to be precise), showed his note, and the stunt became a big hit in Buffalo, with the $5,000 fine the NFL levied against Johnson adding to the legend. "Why so serious?" is a strange rallying cry, but when you've been bad for as long as the Bills have, the fans will seize on anything.
Funny thing is, "why so serious?" is a question that can be asked of Johnson. Off the field he is funny, laid back and easygoing. On it, he is none of those things, and never has been, from his earliest days as an athlete.
"You would never know it's the same person off the field," Britney says. "I'm scared of him on the field, but off the field, I can take him."
And it's not just football that changes him, it's anything competitive. When the bill came after dinner, he wanted to play "Rock, Scissors, Paper" to determine who paid. He is in charge of Team Johnson's volleyball team at family reunions. He recruits relatives beforehand based on their height.
"I had to fire a few family members," he said. "They weren't getting the job done."
It's hard at first to reconcile these two Stevies. He is as likeable an athlete as I've met. I was half an hour late because I went to the wrong Japanese steakhouse (who knew Buffalo had so many?), yet he greeted me warmly and cared not one bit. When his children wander over when we are talking, he picks them up and props them on his knee instead of shooing them away. The word that best describes is comfortable, in whatever situation he's in.
The difference between the two Stevies is so profound that his teammates joke he quoted the wrong Batman villain. They say he should have picked something from Two-Face.
Soon it becomes clear that the two sides of him are a manifestation of "handle business and have fun."
If he has a bad game—and his definition of bad game is one in which the Bills lose no matter how many catches or yards or touchdowns he has—he is miserable the next day. When he dropped what should have been a game-winning touchdown pass against the Pittsburgh Steelers last season, he was so upset he sent out a Tweet blaming God and punished himself the next day. No TV, no video games, no fun.
He knows he should mellow out after that, but if he has, it's not very much. Then again, with the Bills on the path for the playoffs and Johnson following last year's 1,000-yard receiving season with another one, he's having loads of fun now.
The work ethic behind the motto comes from Johnson's stepfather, Andre Lewis, one of the most influential people in Johnson's life. Johnson refers repeatedly to lessons he learned from Lewis.
One in particular has been helpful in his career: Be versatile. Lewis wanted Johnson to be able to get along with whomever he met on the ball fields, gyms and courts around San Francisco. It explains why Johnson is comfortable in any situation; he has thrived in such wildly divergent places as a junior college in California, the University of Kentucky and Buffalo.
"He was fun to coach," says Danny Calcagno, the head coach at Chabot College in San Leandro, Calif., where Johnson played for two seasons. "He wasn't quite … I don't know if flamboyant is the right word. He was just coming into his own at Chabot."
Johnson, 25, was an unknown when he arrived at Chabot, where he went only because a scholarship to Wyoming fell through at the last minute. But like he did later at Kentucky and at Buffalo, Johnson worked his way into being a key performer and big personality on the team.
"He's probably getting used to being that receiver," Calcagno says. "You know how receivers are."
Calcagno meant that as a compliment—that wide receivers have flair and style. Johnson is a big fan of Deion Sanders' flamboyance, and he's got plenty of Neon Deion in him, minus the cockiness. He carries himself with a likable swagger; he wants to be famous but is winsome in his pursuit of it.
"He's always had that personality," Lewis says. "He was always very sociable, unique in that way. As he grew up and achieved recognition through sports, he never really changed or became arrogant."
That's an important distinction for Johnson. The last thing in the world he wants to be is just another guy, but he also knows there are good ways and bad ways to make a name for himself. Maybe that's why he fits so well in Buffalo. Fans in this hard-working city want to be entertained but won't suffer fools for it.
"You will never see him be that normal, plain person," Britney says. "Something has to be distinctive about him."
That's true on and off the field. Off the field, consider his relationship with Britney. They have been a couple since they were in high school and eloped when Johnson was a student at Kentucky; she had moved there to be with him.
This is spontaneous decision No. 2 that worked out well, and it fascinates me; I've never met anyone who eloped. When I asked Lewis what his reaction was when that happened, he said, "Cool. Right on." That's because he knows what a grounding influence Britney is on Johnson and that she had been with him through the ups and downs of life.
Bills quarterback Ryan Fitzpatrick did not know this about Johnson. When I told him, he said that it perfectly sums up Johnson's personality.
On the field, Johnson's distinctiveness is most obvious in the way he runs routes. He lacks high-end speed, so he has to get open other ways. He gets to the right place at the right time, but jukes and jives and dekes his way there. That makes him hard to cover, says Bills cornerback Drayton Florence, whom Johnson credits with making him better through their battles in practice.
"He's integrated basketball into the football field, like when a guy's doing a crossover or a jab step, he's integrated that into getting off of the line of scrimmage," Florence says. "You'll never really see him get jammed at the line of scrimmage. A guy who runs routes textbook is so much easier to cover. He's bringing that basketball shiftiness into his routes. You can't really read him."
That kind of route running wouldn't work in every offense, but it works in Buffalo's. Gailey's system allows creativity in general, and he has worked even more freedom into the scheme to accommodate Johnson and Fitzpatrick, who has a draw-plays-up-in-the-sand style and quirky sense of humor, so the two get along well.
Johnson (6-2, 210) is fearless catching balls over the middle, a skill he shrugs off as the result of wanting to reward the confidence Fitzpatrick shows in him by throwing the ball to him in the first place.
The unique way Johnson plays the position is due in part to the fact he came to it late. Johnson didn't become a wide receiver until after high school, when he attended a football camp. He had been an all-state quarterback and also played safety (among many other positions) in high school. At camp he was lined up as a cornerback. He looked at the guys he'd be matching up against in the drill, figured he might not be able to cover them but could certainly catch the ball, so he got in the receiver line.
This is spontaneous decision No. 3 that worked out well.
Throw in the God tweet—a spontaneous decision that did not work out well—and a lot of key moments in his life happened in a snap.
"A friend was just asking me the other day, 'What is your addiction?' I don't have any," Johnson says. "I'm not addicted to any material things. He said, 'It could be anything.' I said, 'Maybe the spontaneous lifestyle, not knowing what's going to happen.' You know what I'm saying? The thrill of it."
Back at the restaurant, I notice people at another table are looking at Johnson. They recognize him but don't say anything while he's eating. (I notice someone else at that table drink enough sake from the chef's squirt bottle to kill a horse.) The manager has a Bills tie on. He leaves Johnson alone, too. Buffalo fans are crazy about the Bills but not so crazy they won't let them eat in peace. Later, as we leave, someone shouts, "Go get 'em this weekend, Stevie!"
As dinner winds down, Lewis' name comes up several times. He has worked in the music business for 30 years and gave Johnson a love of music, an industry Johnson dabbles in, too. Lewis stressed that life happens in stages. These new stages often begin with one of the spontaneous moments that make life such a thrill for Johnson.
His football career has been a series of steady progressions, from learning the wide receiver position at Chabot to starring for one year at Kentucky to being taken in the seventh round of the 2008 draft to becoming the Bills' go-to receiver. The next stage is stardom. It's coming soon. He will handle that business. And have so much fun.

subset: commoncrawl


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I gave you a comeback. I said your post was ********..... You didn't answer mine. I said if he Colts had been 10-6 and Peyton had been healthy would they have found a way to resign all of the players and make another run. You never answered that. The answer is, of course they would have........
Why am I a troll because I don't agree with you? Why aren't you a troll then if you disagree with me?
There is a big double standard at play here.......
Well, excuse me......
And you didn't read that my scenario was with the Colts going 10-6 with a healthy Peyton Manning returning...... They would have found a way.... So, do a little reading. They would have been signing on for a run at another division championship and a possible Super Bowl run....
Who said anything about taking pay cuts? The Colts wouldn't have had to to that. Do you think players take less money to play with the Pats?
This is a business. Players go where the money is. The Colts could have kept Manning, traded Luck for a boat load of picks over two seasons and kept most of their good players....
Do you think Mathis would have taken less money to join a good team like the Pats or NY Giants?
Do you think Freeney would accept reworking his deal to take less money to play for the Packers?
Irsay did a number on you. That man lied is *** off the entire season about everything and made sure the season ticket holders were locked in before he starting exterminating the Colts..... All of these draft picks and do mean all of them are 50/50 to be good players in the NFL when you factor in injuries and everything else. That is why they will not rebuild from this mess in three years. That would take an incredible run of good fortune (note I did not say "Luck").........
The die is cast, lets get behind them and see what they can do. You can't fire any owner anyway (damnit)......
Point is the end is near for the Pats it just may take 4 more years before Brady hangs it up and they start to rebuild.
To answer your question to Dgreen the Colts couldn't keep Manning and everyone else plus trade down and draft RG3. That combo would take up 17% of the cap and add in the Freeney and thats another 15%. Keep adding a Dallas clark, Addai, Bracket and the available cap space becomes smaller and smaller.
IRsay said the Colts were 10 million cash over cap and Polain before he was fired said the colts were 8 million cash over cap for last year.
IF you subtract Collins 4 million and no one else leaving the team then your easily well over the cap number even with the expections to the cap ceiling.
Lets go back to your talk about the people who thought that RG3 was a better QB than Luck:
Bill Parcells: He drafted Chad Henne. Quincy Carter? Drew Bledsoe (In a smaller fashion)?
Brian Billick: Do I need to remind anyone of Kyle Boller? Elvis Gerbac? Steve McNair? Tony Banks? Anthony Wright?
Phil Simms: Is he ever right?
So this is my point. You just find some random draft guy who agrees with you and you say "I must be right look at this!" Consider the source.
That's my final comment to you because no matter how much evidence is piled up in front of you to the contrary, You just gonna troll...
So, Parcells, Sims and Billick have no credibility? Several Super Bowls in there. Everyone makes mistakes. You want to go over some of Irsay's draft busts? Bill Polian is probably the best general manager in NFL history. He built Super Bowl teams in three different places and given the opportunity and if he has enough time (he is getting old), he could do it again. I do consider these sources and I find them very credible indeed..... There are others who also agree with them like the folks who wrote the article that started this thread...... So, I repeat, in my eyes, you are the troll here who doesn't know what he talking about in regard to the cap and the talent..... RGIII is going to be a super star, Luck ain't ........
Chad OchocincoWinning is definitely the highest priority, he said. Ive been in the league for ten years now and I dont look at the NFL as a place where I can hoard money and get as much as I can because its the end of the world.
ESPNs Adam Schefter reports that Ochocinco restructured his contract for the 2012 season, lowering his base salary from $3 million to $1 million.
I would like to know what Olblu would be willing to bet on Luck being a bust. I am dead serious. If he isn't a bust I think an IP ban is needed lol
We would not even be able to agree on what was a bust....... Peyton Manning was run out of town to make room for this man. I would think if he isn't 75% of what Peyton has been, he is a bust.... What is your definition and why should I be banned? Why shouldn't you be banned for demanding that I agree with your views?
If he had not done that, Ochocinco would have been out of the NFL..... I don't see these as examples of people taking less to play on good teams. I see them taking less to just stay in the game....
Lloyd took less money to be on the pats and its assinine to suggest he would be out of the league if the pats didn't sign him. He had a better offer from other teams but he want to win.
I could come up more examples but I don't think it would matter.
75% of Peyton has been is a bust? That is just laughable.
My point is if the guy is willing to back-up his opinion with actual fact and not just throw up the :BS: flag I am cool with it. In my opinion, Olblu is just trying to stir up **** and get responses. It's all fascinating to be honest because what has he actually said
"Statistically RG3 was the better QB"
"Statistics can be skewed in any fashion you want."
So which one is it? You have an opinion? That's cool but be consistent and don't just respond in whatever fashion is good for that point.
IF you cut a player their dead money still counts against the cap. Cutting Bracket will save very little in 2012. All that backloading of contracts comes due when the players are cut which is why it doesn't work like your describing.
For the 2012 season the Colts have to play with a cap number of around 82 million because 38 million will be dead money. This is why what you suggest is so ridiculous in the first place. Even with cutting guys they didn't have the money to resign Mathis, Garcon and Tamme.
The meter is pegged again..... The Colts did resign Mathis although I do not know why. If they had not resigned Reggie Wayne, they could have resigned either Tamme or Garcon`
Let's get real here, the colts weren't going to win or even challenge for the superbowl this year, even with Peyton healthy. After last season I think its safe to say change was needed, because for the first time our players were exposed for what they are: undersized, and too relient on Peyton to save the day. Peyton could've come back and been great, but it doesn't change the fact that the other positions on the team were in need of replacement. Peyton wanted a chance to WIN, and as a team the colts could not help him do that. It was time for a change.
Taking luck signals a fresh start, with an apparent change in philosophy as well. We can argue luck vs. Griffin all day, but if we build the rest of the team right, then it won't matter who the qb is, we will always have a chance to win.
I don't agree with you. This team was only two years removed from going to a Super Bowl and won the division championship the year before. Bring Peyton back with that same team and he wins ten games or more and probably gets to the playoffs.... The fresh start you are talking about will be years of losing while Peyton will be in the playoffs and working to get back to the Super Bowl.....
Mark my words: In 5 years, Robert Griffin will be known as a bust. He is a glorified Troy Smith.
"What you do is so loud, I can't hear what you say" -Andrew LuckJunior at the University of Louisville
"If you turn the other cheek, I'm gonna hit you in the other cheek, too" -Charles Barkley
"Ego is edging greatness out" -Rick Pitino
Greenfield-Central High School Alum '14
Follow me on Twitter @steagles1
1000th post - 4/16/12 2000th post - 6/24/12 3000th post - 3/8/13
They tried to resign Garcon but he wanted more money than they were prepared to pay so after Garcon signed elsewhere they went to Reggie. The point is that Reggie was a last resort not the first option.


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The New School
Poetry Forum: Sally Keith and Eleni Sikelianos
Sally Keith's most recent book is The Fact of the Matter. Her previous collections of poetry: Design, winner of the 2000 Colorado Prize for Poetry, and Dwelling Song, winner of the University of Georgia's Contemporary Poetry Series competition. Her poems have appeared in Colorado Review, A Public Space, Gulf Coast, New England Review, and elsewhere. Keith teaches at George Mason University.
Eleni Sikelianos is the author of six books of poetry, most recently Body Clock and The California Poem, which was a Barnes & Noble Best of the Year, as well as a hybrid memoir, The Book of Jon. Sikelianos teaches in and directs the Creative Writing Program at the University of Denver.
Moderated by Robert Polito, director, the School of Writing.
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Long-time User Shares his Model with the COMSOL Community
Phil Kinnane February 23, 2012
As part of COMSOL's commitment to the Multiphysics Modeling community, we offer a forum where COMSOL models and other material can be shared; the Model Exchange. I was just looking through the Model Exchange when I noticed a user from way back had posted their model of a horn antenna.
I remember their model from a COMSOL News story dating back to 2004. Dr. Robert Koslover from SARA, Inc. was in fact featured on the cover of this COMSOL News.
Dr. Koslover and his team are still going strong, and they're happy for everyone to access a 4.2a version of the model in the Model Exchange. Others are also welcome to upload their models here.
Newer PostAn Antenna on a Button
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The fate of Samuel Cutrufelli — the admitted methamphetamine user who shot a 90-year-old Greenbrae man in his home — was in the jury's hands Tuesday after his lawyer made a final effort to discredit the accuser.
Defense attorney Sanford Troy said the Greenbrae resident, Jay Leone — a weightlifting World War II veteran with a gun collection — fabricated a "fish tale" about heroically fending off Cutrufelli during a burglary.
Troy argued that Cutrufelli was there to buy drugs from one of Leone's women tenants, that Leone shot up Cutrufelli even though his life was not in danger, and that Leone tampered with evidence to avoid culpability. Troy said Leone was jealous about a younger man coming to visit one of the women he lived with.
"If you look up 'reasonable doubt' in the dictionary, you're going to see 'People vs. Cutrufelli,'" Troy said Monday, the first day of closing arguments. "We, in the defense, have to prove zip. El Zippo, as they say in Spanish."
"This case stinks like fish that hasn't been in the refrigerator for a week," he added later.
The prosecutor, Dorothy Chou Proudfoot, methodically undercut the defense's theory of events, saying much of its argument is irrelevant, speculative or unsupported by the evidence. Proudfoot said Leone was legally justified in defending himself against a life-threatening intruder.
"There's no ambiguity when you shoot somebody in the head," she said Monday. "You shoot somebody in the head, you're trying to kill them."
Cutrufelli, a 31-year-old Petaluma resident who grew up in Novato, faces a potential life sentence on charges of attempted murder, robbery, burglary and other counts. He did not testify at the trial, which began Oct. 3 before Judge Andrew Sweet.
The shooting occurred at about 10:45 a.m. Jan. 3 at Leone's home on Via La Cumbre. Authorities allege that Cutrufelli, a drug user with an assault record, broke into Leone's home, put a gun to his head, tied his wrists and rummaged through the bedroom for valuables.
Leone said he wriggled his hands free, convinced the burglar to let him use the bathroom, and retrieved one of his guns from the bathroom. In the ensuing gunfight, Leone was shot once in the face and Cutrufelli was shot four times in the body.
The defense said the evidence showed that Cutrufelli was shot once in the back, as though while fleeing. Proudfoot said that the evidence does not prove which way the bullet entered, and that it is irrelevant because Leone was fighting for his life in his own home.
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Pressure Gauge, Liquid Filled, 2-1/2 In
VALUE BRAND| Zoro #: G0039514| Mfr #: 4FLL3
Zoro #: G0039514Mfr. Part #: 4FLL3
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|Zoro #: G0039514 Mfr #: 4FLL3
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Product Description
Pressure Gauge, General Purpose, 2-1/2 In., Basic Gauge Case Material Plastic, Basic Gauge Wetted Parts Brass / Bronze, 1/4 In., MNPT, Gauge Connection Location Center Back, 0 to 3000, psi, Gauge Secondary Range Units kPa, Gauge Secondary Range Values 0 to 20,000, +/-3-2-3 Percent, Gauge Panel Mountable No, Liquid Filled Yes, Gauge Primary Range Smallest Graduation 100, Gauge Case Material ABS Plastic, Gauge Case Color Black
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Application of Genetic Polymorphisms of DNA Repair in The Prediction of Prostate Cancer Susceptibility and Its Clinical Outcome
Recruitment status was: Recruiting
- Full Text View
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- How to Read a Study Record
|Prostate Cancer
|Study Type:
|Study Design:
|Observational Model: Defined Population
Primary Purpose: Screening
Time Perspective: Longitudinal
Time Perspective: Retrospective/Prospective
|Estimated Enrollment:
|Study Start Date:
|March 2005
DNA repair plays a key role in carcinogenesis through the removal and repair of DNA damage induced by endogenous and environmental sources. The DNA repair system included four pathways: 1) Base Excision Repair (BER), 2) Nucleotide Excision Repair (NER), 3) Mismatch Repair (MMR) and 4) Double-Strand Break Repair, including homologous recombination pathway and nonhomologous end-joining repair pathway. Decreased and impaired DNA repair capacity has been reported in various cancers, however, its effect on prostate cancer still under investigated.
Common polymorphisms in DNA repair gene may alter protein function and individual's capacity to repair damaged DNA, hence, influence the cancer susceptibility. Polymorphic variants of DNA repair gene have been found to be associated with cancer susceptibility, but rare studies have investigated their effect on prostate cancer. Since variation in the function of these DNA repair genes also impact a cancer cell's viability or resistance to treatment, genetic variants in DNA repair might serve as a valuable biomarker in forcasting the result of cancer treatment. In fact, some reports have demonstrated the association between polymorphisms of DNA repair genes and results of treatment of various cancers.
For the present study proposal, we focused on several DNA repair genes: X-ray repair cross- complementing group 1 (XRCC1), human oxoguanine glycosylase I (hOGG1), xeroderma pigmentosum complementation group D (XPD), hMSH2, hMLH1 and X-ray repair cross-complementing group 3 (XRCC3), which might have relevance in prostate carcinogenesis based on their known functions. XRCC1 is involved in DNA repair in the base excision pathway, the hOGG1 gene encodes a DNA glycosylase /apurinic-apyrimidinic lyase that catalyzes the excision and removal the 8-OH-dG (8-hydroxy- 2-deoxyguanine) - which is a major form of oxidative DNA damage. The XPD gene codes for a DNA helicase involved in transcription and nucleotide excision repair. The hMSH2 and hMLH1 are genes involved with mismatch repair. The XRCC3 gene encoded a protein in the double-strand break homologous recombinational repair pathways.
In this proposed study, we will also use PCR-based methods to investigate the effects of DNA repair gene polymorphisms on prostate cancer susceptibility, pathological grade, disease stage and clinical outcome. With these efforts, we will further understand the association between DNA repair gene polymorphism and prostate cancer and provided important information for screening, prevention and treatment of prostate cancer.
|Ages Eligible for Study:
|Child, Adult, Senior
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- prostate cancer approved by pathology
Exclusion Criteria:
- combined with other malignancy
- accepting blood transfusion within 6 months
Please refer to this study by its ClinicalTrials.gov identifier: NCT00167024
|Contact: Chao-Yuan Huang, MD
|886-2-23123456 ext 5238
|National Taiwan University Hospital
|Taipei, Taiwan
|Contact: Chao-Yuan Huang, MD 886-2-23123456 ext 5238 email@example.com
|Principal Investigator: Chao-Yuan Huang, MD
|Principal Investigator:
|Chao-Yuan Huang, MD
|National Taiwan University Hospital
|ClinicalTrials.gov Identifier:
|NCT00167024 History of Changes
|Other Study ID Numbers:
|Study First Received:
|September 12, 2005
|Last Updated:
|November 25, 2005
Keywords provided by National Taiwan University Hospital:
prostate cancer, DNA repair gene, genetic polymorphism
Additional relevant MeSH terms:
Prostatic Neoplasms
Genital Neoplasms, Male
Urogenital Neoplasms
Neoplasms by Site
Genital Diseases, Male
Prostatic Diseases
ClinicalTrials.gov processed this record on September 19, 2017


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Bullitt East junior Michael Murphy watches his shot to the green on the 9th hole at Heritage Hill Golf Course last Wednesday. Murphy was playing the Bullitt/Hardin Challenge.
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Boston State-House is the hub of the solar system. [Holmes, "Autocrat of the Breakfast Table"]
[E]verybody knows that Boston used to be called the Hub, meaning the hub of the universe. It may still be the hub, because the center of a wheel moves slowly. [J.P. Marquand, "Life," March 24, 1941]


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The SUNY Orange web site strives to be in compliance with the Accessibility of Web-based Information and Applications, published by the New York State Office for Technology:
- NYS Information Technology Policy NYS-P08-005 (PDF 157 KB)
Images on this web site contain the "alt" attribute. This attribute provides a description of the image for users who listen to the content of the web site using a screen reader, rather than reading the web site.
Most information that is made available on our web site is generally available in HTML. In some cases we may publish documents using Adobe's Portable Document Format (PDF). We also strive to provide those same documents in plain text format or in their native applications.
If you use assistive technology and the format of any material on our Web site interferes with your ability to access information, please use our point of contact listed below for assistance. To enable us to respond in a manner most helpful to you please provide us, where possible, with the following information:
- the nature of your accessibility problem
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- your contact information
If you have any questions or concerns about the accessibility of any part of this web site, please contact us by emailing the following address: firstname.lastname@example.com. You may also contact Chris Thurtle, Assistant Director of Communications for New Media, at: (845) 341-4402.
If you need to contact the College via TDD equipment, please dial 711 on your telephone, and then dial (845) 341-6222.


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New York -- With retail books closed prior to Hurricane Sandy's arrival in the Northeast, most retailers experienced same-store sales gains for the month of October, some with stronger showings than others.
The 17 retail chains tracked by Thomson Reuters are predicted to report 4.3% growth in October same-store sales, up slightly over the 4.1% advance reported in the year-ago period and a significant gain over September's 0.8% rise.
Among specialty retailers, Gap and Limited showed the greatest muscle in a weaker October category, with lifted same-store sales of 4% and 3% respectively.
Gap Inc.'s swing to a 4% same-store sales gain in October from its 6% decrease in the same period last year represented measurable strides for the company, said CEO Glenn Murphy. "We're very pleased with the continued momentum in the business across all brands in North America," said Murphy. "Our focus remains on offering great product to our customers in order to sustain our business performance." By brand, Gap North America recorded a 6% Oct. same-store sales gain versus negative 5% last year, Banana Republic North America was up 5% versus up just 1% last year, and Old Navy North America recorded a 5% same-store sales gain versus negative 9% last year.
For the quarter, Gap reported an 8% increase in net sales to $3.86 billion, and it has raised its third-quarter guidance 60% over last year.
At Limited Brands Inc., sales momentum slowed as the October 2012 same-store sales gain of 3% missed Wall Street's expected 5% rise. Victoria's Secret was the big disappointment as same-store sales growth slowed to 3% while analysts expected a 6.1% gain.
The Buckle surprised with a 3.8% same-store sales rise, when a decrease of 1.3% was expected.
Other same-store sales results among the specialty retail category include:


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- You must be 21 years or older to adopt from Pups In Peril.
- Dogs are placed as companion pets only. Our dogs will not be placed as strictly guard or protection dogs or hunting dogs.
- If you rent or lease your house or apartment, we require written or verbal consent from your landlord before adopting a dog.
- We require homes with secure fencing, unless living in an apartment, those potential adopters will be considered on a case to case basis.
- NO dog will be adopted to be kept strictly outside, all our dogs are inside dogs.
- All dogs will be spayed or neutered before adoption is finalized.
- We do not suggest puppies for a family where all family members are gone for long periods each day.
- A home check is required before adoption can be finalized.
- Veterinarian references will be checked before adoption can be finalized.
- If at any time you can no longer care for a dog adopted from Pups In Peril, you are required to return the dog to Pups In Peril.
-Pups In Peril reserves the right to refuse any adoption.
Thank You!
Your message has been sent to Pups In Peril.
You'll receive a copy, too, at to help you keep track of which pets you've inquired about, and which shelters and rescues you've emailed.
NOTE: Some shelters have physical locations you can visit; some of these shelters may only have pets for a limited time, so please do not wait for a reply—just go visit the shelter! Other organizations are rescue groups run by busy volunteers who may take a while to reply. You can find information about the shelter or rescue group caring for this pet, and their adoption procedures, on the pet's details page on Adopt-a-Pet.com.


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One of the investment options our firm offers to our clients is an equity overlay. The individual-stock strategy adds alpha to portfolios, and gives investors exposure to some of the names with good long-term growth potential.
In the interest of generating some ideas for this portfolio, I ran my scan for the best performers from the ranks of big-cap stocks. One name that popped up for the first time in months was Salesforce.com (CRM).
The maker of customer relationship management software has a market cap just shy of $24 billion. It moves an average of about 1.8 million shares per day. Despite being a large stock with good liquidity, Salesforce.com is still prone to some volatile trade, as evidenced by its beta of 1.41.
During Wednesday's market rally, the stock rallied to an all-time high of $173.96. As with many stocks these days, it's extended from a reasonable buy point, so a pullback may offer the next opportunity.
This name falls solidly under the definition of "growth stock." Salesforce pays no dividend, but has offered good price appreciation. Despite struggling during the spring and summer of 2012, it finished the year with a gain of 66%, to $168.10. Analysts are projecting earnings of $1.52 per share this year, up 9%. In 2014, that's expected to rise another 32%, to $2 per share.
Valeant Pharmaceuticals (VRX) is another large-cap stock with good prospects. This stock fell off my radar this year when it plunged 12.5% in May after reporting a first-quarter loss as part of its dermatology unit selloff. Nonetheless, Valeant finished 2012 with a 28% gain to $59.77. The company makes treatments for nervous system disorders and other ailments.
Like numerous other stocks, Valeant ran up to a new high on Wednesday. In Thursday's session, it surged to $61.60, a penny short of Wednesday's intraday peak. This, too, is showing a bit of froth at the moment, so it's not the optimal time for new buyers. Watch for a pullback to its 50-day or even 200-day line.
The company's earnings picture is bright. It's expected to report its fourth quarter results next month, delivering earnings per share (EPS) of $4.54. That would be a 55% year-over-year increase. This year, it's expected to earn $5.66 per share, a gain of 25%.
The third stock that showed up on my top large-cap screen was ARM Holdings (ARMH). The U.K.-based company is on the cutting edge of the "wearable computing" trend -- that is, chips incorporated into clothing and other gear. It specializes in power-efficient chips. It's a supplier to Apple (AAPL) as well as Samsung.
The chip sector is notoriously cyclical, and you don't have to look far to find pundits who are both bullish and bearish on the stock. I'm indifferent, and have no horse in the race. However, the company's current fundamental and technical indicators show some promise.
The stock gapped up to a new high Wednesday, $39.07. It's far extended from both its 50-day and 200-day lines, and is most definitely out of buy range. However, the fundamental potential makes the stock worth watching. Analysts expect the company to post 2012 earnings of $0.70 per share, a 21% year-over-year gain. It's expected to report fourth-quarter and yearly results early next month. For this year, analysts have pegged earnings growth at 26%, to $0.88 per share.


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Even though today marks the first full day of winter, natural gas prices fell on the report week at most market locations. The Henry Hub price flirted with the sub-$3 per MMBtu mark, but ultimately ranged within $3.01 per MMBtu and $3.08 per MMBtu, ending the week three cents below its value last Wednesday. Although Northeastern prices increased with cold weather, they eventually fell by the end of the report week. Forecasts for colder temperatures across most of the country heading into the weekend, however, could lead to some gains in prices.
Supply fell slightly this week, yet remained 4 percent above year-ago levels, the result of continued strength in domestic production. Imports from Canada fell by 3.2 percent from the previous week, with only the West posting increases from last week, according to Bentek. LNG sendout declined overall this week. Almost all recent LNG sendout has come from the Elba Island LNG terminal in Georgia and the Everett LNG terminal in Boston, according to Bentek. Demand declined on the week despite rising somewhat mid-week.
Rockies prices this week were generally an exception to the net declines seen in other parts of the country. Prices in the Rockies jumped in the second half of the report week, as snow and cold temperatures hit the area. The spot price at the Opal Hub in Wyoming, a proxy for Rockies prices, rose from $3.02 per MMBtu last Wednesday to $3.18 per MMBtu yesterday. According to data from Bentek, demand for power and residential and commercial heating climbed to 3.7 Bcf, a 0.8 Bcf increase from the previous day. Forecasts for colder temperatures likely drove up the Rockies prices at the end of the week. Although the Ruby Pipeline, which moves Rockies natural gas west, came back online this week after force majeure, Rockies outflows declined.
At the NYMEX, the January 2012 contract posted a small gain over the report week, rising from $3.136 per MMBtu last Wednesday to $3.155 per MMBtu yesterday. The contract recovered losses from earlier in the week; on Monday, the contract ended the day at $3.096 per MMBtu. The 12-month strip (the average of the 12 contracts between January and December 2012) followed a similar pattern, rising from $3.405 per MMBtu last Wednesday to $3.430 per MMBtu yesterday.
Working natural gas in storage fell to 3,629 Bcf as of Friday, December 16, according to EIA's WNGSR. This represents an implied net withdrawal of 100 Bcf, slighty less than the previous week. The draw was much smaller than the 5-year average draw of 140 Bcf as well as last year's draw of 181 Bcf.
For the second week in a row, the West Region saw a relatively large draw. While the East and Producing Regions continue to draw less gas compared to historical averages, the West Region drew significantly more. Slightly colder weather combined with a temporary outage to the Ruby Pipeline, which carries gas to the region, are likely responsible. All regions remain well above 5-year average levels.
Temperatures during the week ending December 15 were 1.9 degrees warmer than the 30-year normal temperature and 5.7 degrees warmer than last year. All regions except the Mountain and Pacific experienced relatively warm temperatures during the week. Those two regions, largely comprising the West storage region, were respectively 1.0 and 3.1 degrees colder than the 5-year average. Nationwide, heating degree-days were down 6.2 percent from average and 17.3 percent from last year.


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Click Click Here to view this Link.- Here to view this Link.-
AUBURN -- What are you thankful for?
That question will be asked today in households across America. The scene conjures thoughts of a family, seated at a long rectangular table full of turkey, taking turns discussing their blessings.
Not quite the visitor's locker room in Bryant-Denny Stadium at halftime of the Iron Bowl.
Still, that's where Nick Fairley pondered thankfulness while Auburn was trailing Alabama 24-7 at halftime of the 2010 Iron Bowl.
Jeffrey Whitaker wasn't even supposed to be playing much in that game. Senior defensive lineman Mike Blanc and Michael Goggans had been suspended for the first half of the Iron Bowl for throwing punches the previous week in a fourth-quarter scuffle against Georgia. Whitaker was a true freshman suddenly thrust into a substantial role for the biggest game of the season.
"We came out for warmups, and I've never heard that many words that I can't repeat," Whitaker said. "They were directly at me. As an individual you felt like they pointed you out, and they let you know how they feel. It was awful. As a freshman, I'm going, 'Oh my god.'"
The shock carried over to the first half. Facing a 17-point deficit at halftime, Whitaker wasn't expecting the kind of pep talk Fairley delivered.
"I know some movies (have) all these speeches, but this ain't how it's supposed to be right there," Whitaker recalled.
The 2010 Iron Bowl fell on the Friday after Thanksgiving, so the players spent the holiday with the team instead of their families. Whitaker said the night before the game various coaches and players got up in front of the team and discussed their gratitude.
The thankfulness carried over to the individual position meetings -- and even to the pre-game breakfast that Friday morning. But the defensive line didn't get a chance to finish its meeting.
Twenty-four points later, nothing on the field demanded gratitude. But Fairley's question at halftime created the image that Whitaker remembers first when he thinks about that game.
What are you thankful for?
"Each defensive lineman went around and said what they were thankful for," Whitaker said. "And (Fairley) said let's just go out and fight and let the chips fall where they fall."
At that point, it was bigger than football.
Different players gave different answers. Some were thankful for family -- the look on their daughter's face when she first saw him after a game - while others simply were thankful for the experience of playing college football.
"It was a great moment," Whitaker said. "That's something that I will cherish. That memory will be with me for life."
The second half of that game also will be with any Auburn fan's memory for life.
The Crimson Tide gained only 58 yards in the second half while Auburn roared back to the 28-27 victory that paved the way for a SEC Championship and BCS National Championship.
Those few minutes at halftime are what stick out to Whitaker.
"It isn't like I walked out of here and I had cancer," he said. "It ain't like I walked out of here and heard that someone died who was close to me. Sometimes football is overhyped. But I think it's the greatest life lesson of all-time in these sports. In life, you're going to be 3-8. Things aren't going to go your way all the time, but it's just all about keep swinging.
The trials Whitaker has endured far outweigh the outcome of a game. He lost his mother when he was 12 and said he could have folded in the face of that adversity.
"Look at me now," Whitaker said.
Many people indeed will looking at Whitaker and the rest of the defense Saturday afternoon. And now being one of the veterans of the defensive line instead of a wide-eyed freshman, he'll repeat what Fairley told him two years ago.
"We want to play for each other, and we want to keep swinging for each other," Whitaker said. "Those are my brothers. It's the last game, so we're going to lay it on the line and let them chips fall where they fall."


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1.3.6 Progress
This week I fixed a few more issues for the upcoming 1.3.6 release. Everything is in the 1.3.6 branch in SVN. There are a few more bugs that need to be fixed before we can release. One that's particulary nasty is #2864380. The memory leak only occurs if client or server certificate validation is performed (Context::VERIFY_RELAXED or Context::VERIFY_STRICT). Now the strange thing is that the NetSSL code does nothing special in this case, it just affects the call to SSL_CTX_set_verify() in the Context constructor. So either the leak is in OpenSSL (which I don't really believe), or we're using OpenSSL in an inappropriate way. If anyone could take a look at this issue, this would be highly appreciated.
Update 2009-11-16: I found and fixed the NetSSL memory issue.


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A PIONEERING scheme has been launched in Benfleet to help children who get a rare condition after brain tumour surgery.
The Danny Green Fund and Benfleet Physiotherapy, in Rayleigh Road, Thundersley, are helping provide specialist treatment for children with posterior fossa syndrome.
The rare condition, which is found after a brain tumour has been surgically removed from the brain stem, leads to poor balance, loss of speech, and weakness on one side of the body.
Now, youngsters will be able to get one-on-one physiotherapy and hydrotherapy at the Thundersley centre to aid their recovery .
The company has volunteered its expertise and chipped in £1,000 a year to help fund the sessions.
Benfleet Physiotherapy owner Nigel Kimpton said: "We've been running our clinic for 25 years and we've grown to such an extent we can now offer help to children.
"We are just so impressed by what the charity does for children with posterior fossa syndrome so we wanted to offer our expertise.
"We hope this will be really beneficial to the community. We are treating a three-year-old girl who hasn't been able to walk before, but three weeks ago, she took her first steps.
"It's extremely rewarding to see the joy of a family when we can help give them some normality so we are happy to help."
The Danny Green Fund was set up by the family of 11-year-old Canvey lad Danny, who he lost an eight-month battle with brain and spinal cancer in July 2012.
He suffered the effects of posterior fossa syndrome, and was unable to lift his head or walk.
Now his family give up their time to provide information about the condition and support to others who have it.
Danny'smum, Lisa Green, said: "The fund is looking forward to working with Nigel and his team of physiotherapists who provide a friendly and professional service.
"Specialist input is essential in helping children who are suffering from the syndrome to maximise their potential and build upon the initial recovery they have made.
"Together, we are going to maximise each child's potential and restore lost skills."
For more information e-mail firstname.lastname@example.com


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St. Johns Bay Rum Cutlass Cologne
By St. Johns Bay Rum for Men
St . Johns Bay Rum Cutlass Cologne by St. Johns Bay Rum, Released by the west indies bay company, st johns bay rum cutlass is a fresh, spicy and carefree scent for the rugged man with a soft spirit. Opening top notes are comprised of mediterranean bergamot and west indian lime. Middle heart notes of cedar, violet, orange blossom and white lavender mix with base notes of patchouli, soft ferns and subtle spices to create a mysterious masculine fragrance perfect for the man who likes to add a ... Read More ... Read More little bit of spice to life. All products are original, authentic name brands. We do not sell knockoffs or imitations.
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I received exactly what I ordered, and everything came through on time and in excellent shape. Thank you.
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The Central Brevard Humane Society provides an animal welfare shelter and programs that foster a humane ethic toward all animals. We also strive to deepen the community's commitment to spaying and neutering, as well as to the adoption of homeless companion animals. We believe this to be essential to achieving our purpose of humane care and treatment of all animals.
At the time of adoptions, an additional $10.00 per cat/dog is collected for tag license fees required by the Brevard County Animal Control Services, plus a $2.00 handling fee. A $15.00 fee is also collected, if we have administered a rabies vaccine to the animal.
We accept cash payments, debit cards and credit cards (VISA, Master Card & Discover).
Carrie (Merritt Island Adoption Center)
Cleopatra (Merritt Island Adoption Center)
Jodi (Merritt Island Adoption Center)
Kitty (Merritt Island Adoption Center)
Thank You!
Your message has been sent to Central Brevard Humane Society.
You'll receive a copy, too, at to help you keep track of which pets you've inquired about, and which shelters and rescues you've emailed.
NOTE: Some shelters have physical locations you can visit; some of these shelters may only have pets for a limited time, so please do not wait for a reply—just go visit the shelter! Other organizations are rescue groups run by busy volunteers who may take a while to reply. You can find information about the shelter or rescue group caring for this pet, and their adoption procedures, on the pet's details page on Adopt-a-Pet.com.


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Driver Red and Revolver Girl...
Kuso Vinyl is taking their own brand of designer toys on the road with two San Diego Comic-Con 2012 exclusives. Hit booth #4937 for the opportunity to pick up Crappy Cat "Driver Red" by artist VanBeater (pictured top). Standing 2.75 inches tall, Driver Red will be limited to only 200 pieces worldwide. Each figure is packed in the bag with header card and priced at an affordable $10. VanBeater will be signing for the fans on Thursday, 12th from 12pm to 2pm.
Also at booth #4937 will be Revolver Girl "Barenaked Edition" by Rotobox Vinyl Anatomica (pictured below). Limited to a mere 100 pieces, Revolver Girl comes with 2 guns, a removable towel, and a mini comic. She will be priced at $75. Rotobox will attend the Con this year to sign your figure, though a signing schedule has not yet been determined.
To insure your action figure collection, get in touch with Collectibles Insurance, the official insurance company of the Figures.com network. Say "Figures.com" to get 5% off your first term premiums.
To buy action figures, take a look at BigBadToyStore.com, RedfordFilms.com, Toynk.com, PastGenerationToys.com, BriansToys.com, ToyWiz.com, and MonkeyDepot.com.


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2014 Membership Form
LRS Application
LRS Rules & Procedures
Award Application
Lawyer Referral Service
The Bristol County Bar Association
is a service organization
comprised of attorneys dedicated to improving the quality
of the practice
of law and providing support
to the community, the bench,
and the bar on issues relevant to the local community.
The Bristol
County Bar Association counts
among its members some of the most respected attorneys in
Massachusetts. We are proud to be a
responsive, innovative and active Bar Association whose members
take leadership roles at
the local, state and national level.


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Moderators: Timko, Fritz, Solty, Booter, Blake_T, Frank Delicious
keltik wrote:how tall are you?
EDIT: what course are you playing in the second vid?
keltik wrote:being as tall as you are you have a lot of leverage to work with. you don't reach back and you don't use your legs or core effectively or at all. it basically looks like you're not trying. you also look like you are strong arming.
that course looks fairly short; you should really try playing it using mainly your Buzzz or Putter off the tee. the best first step to building distance is learning how to throw a putter 300'.
read that thread completely.
keltik wrote:holy nose up batman! your weight is not forward.
JR wrote:Your heart should be as close to the target as your right knee as the disc rips out. You never got there.
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Snug as a rug in a bug(gy)!
A lightweight, soft-shelled baby carrycot with a zip away top cover, cocoon will keep your baby snug & warm in their stroller. Carry handles and a firm base allow you to lift baby in & out of the stroller without disturbing their rest.
Thanks %user_name%
Your review has been sent for 'review'!


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SAN FRANCISCO — Fast Retailing will open its first West Coast Uniqlo flagship store in the Union Square neighborhood of San Francisco.
The 29,000 sq. ft., three-story store is set to open on Oct. 5 at 111 Powell Street. The store will feature high-beamed ceilings, a large basement to roof skylight, an LED-illuminated rainbow staircase and 77 LCD screens lining the perimeter of the store on seven large monitor walls featuring a rotational mix of marketing campaigns and product promotions. In addition the store will feature the company's first "Magic Mirror" technology enabling customers to virtually try on clothes.
"Friday will be a landmark day for Uniqlo as we open our doors on the West Coast. We look forward to welcoming customers into our San Francisco flagship store and sharing our innovative products and brand philosophy with the Bay Area," said Uniqlo USA COO Yasunobu Kyogoku. "San Francisco is the center of global innovation and we are delighted to join this vibrant community."


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Two items – one involving funding the Pomona Economic Opportunity Center and the other calling for funding for the Chamber of Commerce – will go to the Pomona City Council Monday night.
City administrators are recommending the council authorize providing $50,000 in funding to the center for the 2012-2013 fiscal year, according to a city staff report.
Funding for the center, often referred to as the Pomona Day Labor Center, would come from the general fund general services budget which contains money for general government expenses such as dues for government associations, for some contract services and for contingencies.
The city has been decreasing the amount of funding it has provided to the center in recent years due to limited availability of funds.
Between the 2003-2004 and 2010-2011 fiscal years the city, through the now-defunct redevelopment agency, provided funding for the center.
In the 2006-2007 fiscal year the center was allocated $220,000, the highest amount during that period, according to the staff report.
Administrators are also recommending city leaders appropriate $24,000 from general fund reserves to provide financial assistance to the Chamber.
Part of the money – about $9,000 – would pay the Chamber's rent for its office in the Mission Promenade for the first six months of the current calendar year, the staff report said.
The report said $15,000 would be used to purchase sponsorships. An additional $1,267 from the city's general fund would be used to pay for the city's membership in the Chamber of Commerce through March 2014.


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CONCORD — Kindergarten teacher Janice Winsby got an unwelcome call from her bank on Christmas Eve: Someone had been using her credit card.
Although Winsby knows this type of thing happens often, she's more concerned than usual because she received a letter from the Mt. Diablo school district two days earlier saying a laptop containing confidential employee information had been stolen from the district office.
"I thought maybe I should call the Concord Police Department because they were the ones investigating the burglary," Winsby, a teacher at Cambridge Elementary School, said Friday. "But I haven't done it. It's kind of hard to prove any connection."
Still, Winsby and other employees are wondering whether the security breach that affected nearly 16,000 district employees and retirees — along with about 2,200 current and former employees in the Berkeley school district — could lead to identity theft.
The Dec. 18 letter sent to Mt. Diablo employees said the information was related to people who worked in the district between 1998 and 2010. But retired teacher Pat Teschner said she has been contacted by three retirees who received the letter even though they left the district earlier than 1998, including one who retired in 1993.
"She's in her early 80s and was very confused and frightened by it," Teschner said. "And she would like to know if it applies to her or not."
Chief Financial Officer Bryan Richards said the data was transferred to his laptop from a computer that had been used by the previous chief financial officer. A Berkeley district payroll file was also on the laptop, according to a Friday letter from Mt. Diablo Superintendent Steven Lawrence to affected Berkeley employees.
"We believe a former Berkeley Unified School District employee who then came to work for the district and has since left inadvertently transferred the file to the district's computer," Lawrence wrote.
Berkeley school district spokesman Mark Coplan said the person believed to have accidentally taken the information to Mt. Diablo was a short-term, temporary Berkeley employee. Coplan said his district sent a letter to affected employees the week before Christmas to inform them about the breach.
"We want our employees to know about it and that police are following up and that Mt. Diablo is taking care of it," he said. "But we really don't anticipate anyone's information actually being used."
The Mt. Diablo district offered its employees and retirees a free one-year membership in an identity theft protection program. The district is also offering the membership to affected Berkeley employees.
Mt. Diablo district employees also received contact information for credit reporting agencies and the Federal Trade Commission, along with a suggestion to contact police or the state Attorney General's Office if identity theft is suspected. FTC attorney Evan Rose said people whose confidential data has been stolen should monitor their credit cards and bank accounts closely and request free credit reports from each of the three credit reporting agencies every four months.
If they believe they are the victims of identity theft, they can file police reports and place fraud alerts or freezes on their credit, he added.
Winsby, who previously worked in Chevron's information technology department, wonders why the information was on the laptop at all.
"It seems to me that data like that should not be on a computer," she said. "A lot of questions need to be answered."
Those affected by the security breach can call Mt. Diablo school district General Counsel Greg Rolen at 925-682-8000 ext. 4001.
Information about identity theft protection is available by calling the Federal Trade Commission at 877-438-4338 or going to www.FTC.gov.
For additional details about the Mt. Diablo burglary, read the On Assignment blog at http://www.ibabuzz.com/onassignment.


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text:
Trial Comparing Three Strategies of Vaccination Against the Virus of Hepatitis B in HIV Infected Patients (VIHVAC-B)
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
In HIV infected patients, individuals exposed to the virus of Hepatitis B are more susceptible to develop a chronic and severe liver disease with a major risk of cirrhosis and liver cancer.
However, the existing protocol of vaccination against Hepatitis B is less efficient in HIV-infected patients than in non HIV-infected-patients, and, in case of response, its longevity has to be followed up carefully. This study compares the efficacy of the standard protocol vaccination with GenHevac-B and 2 other protocols, a double-dose of GenHevac-B and a set of intradermal injections of Genhevac-B, in HIV-infected patients with lymphocytes T CD4 level above 200 permm3.
|HIV Infections
|Biological: GenHevac B Pasteur
|Phase 3
|Study Type:
|Study Design:
|Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Prevention
|Official Title:
|Open-label, Randomized, and Multicentric Phase III Clinical Trial Comparing Three Strategies of Vaccination Against the Virus of Hepatitis B in HIV-1-infected Patients With CD4-positive T-lymphocytes Counts Above 200 permm3 ANRS HB 03 VIHVAC-B
- HIV-infected patients who seroconvert in the first two months after the last vaccination. Seroconversion is defined as antibodies AbHBs titers equal or above 10 mUI per ml. [ Time Frame: two months after the last injection;week 28, month 18, month 30 and month 42 ]
- According to the vaccine administration (IM or ID) comparison of AbHBs titers,permanence of the humoral response,intensity of clinical and biological events and predicting factors related to seroconversion [ Time Frame: two months after the last injection; week 28, month 18, month 30 and month 42 ]
|Study Start Date:
|June 2007
|Study Completion Date:
|September 2012
|Primary Completion Date:
|December 2008 (Final data collection date for primary outcome measure)
|Assigned Interventions
Active Comparator: A
GenHevac-B 20 microgramme Intramuscular use at M0, M1, M6
Biological: GenHevac B Pasteur
Intra-muscular injection 20 microgramme Intramuscular use at M0, M1, M6
Other Name: Sanofi Pasteur MSD
Experimental: B
GenHevac-B 40 microgramme Intramuscular use at M0, M1, M2, M6
Biological: GenHevac B Pasteur
Intra-muscular injection 40 microgramme intramuscular use at M0, M1,M2, M6
Other Name: Sanofi Pasteur MSD
Experimental: C
GenHevac-B 4 microgramme Intradermal use at M0, M1, M2, M6
Biological: GenHevac B Pasteur
GenHevac-B 4 microgramme Intradermal use at M0, M1, M2, M6
Other Name: Sanofi Pasteur MSD
Detailed Description:
Comparison of 3 vaccination strategy against Hepatitis B in patients with HIV infection T CD4 above 200 per mm3
- Arm A: GenHevac-B 20 microgramme Intramuscular use at M0, M1, M6
- Arm B: GenHevac-B 40 microgramme Intramuscular use at M0, M1, M2, M6
- Arm C: GenHevac-B 4 microgramme Intradermal use at M0, M1, M2, M6
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
Age Eligible for Study: 18 years - NA, Genders Eligible for Study: Both
Inclusion criteria:
- HIV infection
- T CD4 count cell level above 200 per mm3
- Serology Hepatitis B negative (AgHBs, AbHBs and AbHBc negative)
- unchanged ARV for the last 3 months for patients who are receiving ARV at the screening visit
- Undetectable for the last 6 months with ARV for any patient with T CD4 level below 350 per mm3
- Pregnancy test negative at the screening and inclusion visits
Exclusion Criteria:
- Any injection of the vaccine against Hepatitis B in the medical history
- Acute cytolysis in the last 3 months with transaminases equal or above 5 times the upper normal range for HIV-HCV coinfected patients, or transaminases equal or above 2 times the upper normal for non coinfected patients
- Any vaccine received one month before the inclusion
- History of intolerance to any component of GenHevac-B
- Evolutive opportunistic infection treated the month before the screening visit
- Severe and acute pyretic infection or unexplained fever the week before inclusion
- Evolutive hemopathy or solid-organ cancer
- Prothrombin factor equal or below 50 percent and/or platelets equal or below 50 000 per mm3
- Immunosuppressive treatment or general corticotherapy (equal or above 0,5 mg per kg per day during above 7 days) in the last 6 months before the screening visit
- Previous Immunomodulating treatment (interferon, interleukin-2,etc) or plan in the next 6 months
- Splenectomy
- Decompensated cirrhosis (Child Pugh B or C)
- Kidney deficient function (creatinine clearance below 50 ml per mn)
- Other immunocompromised condition not related to HIV infection (solid-organ transplantation, chemotherapy in the last 6 months)
- Any participation to another clinical trial plan until Week 28
Please refer to this study by its ClinicalTrials.gov identifier: NCT00480792
|Hopital Cochin CIC de vaccinologie
|Paris, France, 75014
|Principal Investigator:
|Odile Launay, MD
|CIC de vaccinologie Cochin-Pasteur 27, rue du Fb Saint Jacques 75014 Paris Fr
|Study Chair:
|Fabrice Carrat, MD
|Inserm U707 27, rue de Chaligny 75571 Paris cedex 12 Fr
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
|Responsible Party:
|French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS)
|ClinicalTrials.gov Identifier:
|NCT00480792 History of Changes
|Other Study ID Numbers:
|Study First Received:
|May 30, 2007
|Last Updated:
|July 22, 2013
Keywords provided by French National Institute for Health and Medical Research-French National Agency for Research on AIDS and Viral Hepatitis (Inserm-ANRS):
Hepatitis B vaccination
GenHevac-B Pasteur
HIV Infections
Additional relevant MeSH terms:
HIV Infections
Hepatitis B
Liver Diseases
Digestive System Diseases
Lentivirus Infections
Retroviridae Infections
RNA Virus Infections
Virus Diseases
Sexually Transmitted Diseases, Viral
Sexually Transmitted Diseases
Immunologic Deficiency Syndromes
Immune System Diseases
Hepadnaviridae Infections
DNA Virus Infections
Hepatitis, Viral, Human
Immunologic Factors
Physiological Effects of Drugs
ClinicalTrials.gov processed this record on September 21, 2017


text: Since 1923 Red Kap has been supplying workwear made for those who needed it most. Comfort, durability and great service were valued every bit as much back then as they are today, and those qualities are shared by G&L Clothing, and expressed by our great selection of High Visibility and Flame Resistant Red Kap work clothes. Browse our selection below, and place an order with us today!


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Average farmland values in Iowa increased by over five percent to reach historic levels in 2013 according to the Iowa Land Value Survey conducted in November.
Farmland values increased for the fourth consecutive year with farm income motivating sales. A release from Iowa State University Extension says corn and soybean price movements are good indicators of gross farm income movement and both grains have fallen over the past year.
Although farmland price increases started to slow after June as buyers became more concerned with lower grain prices, county averages were as high as $12,413 per acre. Scott County, the county with the highest average, saw values increase by 12.45 percent, averaging $1,374 per acre more this year than in 2012.
Michael Duffy, Iowa State economics professor and extension farm management economist who conducts the survey, keyed in on the slowing growth and inquires about the direction of the market in 2014.
"The key question is if this shows the market is going to settle, if it is just pausing before another takeoff in values, or if the market has peaked and due for a correction," Duffy said.


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These illustrations from Tokyo-based artist Sagaki Keita prove that the doodles on your notebooks can come in handy… if you plan to pursue them on a bigger canvas and have the patience. Keita's work is composed of numerous small-scale characters. From a distance, his illustrations look like great ink renderings of cultural works such as the Statue of Liberty and the Great Wave, but once you get close, every inch of the piece can be analyzed and appreciated for the attention to detail.
Via MyModernMet.


text:
Pacers trade: Rush, Jones, McRoberts, Posey and 2012 1st rnd draft pick - lottery protected, 2013 2nd rnd pick.
Pacers get: Josh Smith, Vince Carter, Markeiff Morris.
Suns trade: Carter, Lopez, Morris.
Suns get: James Posey, Brandon Rush, Keith Benson, Pacers 2013 2nd rnd pick.
Hawks trade: Smith, Benson.
Hawks get: Robin Lopez, Josh McRoberts, Dahntey Jones, Pacers 2012 1st rnd pick - lottery protected.
Suns are trying to buy out Carter's contract. I would think they would show interest on trading him to open their cap space.
This would allow to resign Brooks and whoever else they need to fill needs.
S&T Josh - Pacers have rookie rights on Josh.
Brandon Rush, Dahntey Jones, James Posey - Dropped 13 million.
Jeff Foster 2 yrs. 3mil.
Aaron Gray 3 yrs. 4.5mil.
Matt Howard 500k 1yr.
Markieff Morris 1.5mil. for 1st yr.?
Josh Smith's contract is only 2 yrs. So, he shouldn't mess with our extensions on DC & Hans.
Approx. figures on salaries
37-13=24+18=42+12=54+1.5=55.5+1.5=57+1.5=58.5+.5=59mi llion.
18 million is Carter's which comes off at end of year.
Will put Pacers back down to 40.5mil at end of year and able to sign Hibbert and Hill extensions.
I just threw Gray in line up for head count & salary fill.
Roy Hibbert / Arron Gray / Jeff Foster
Josh Smith / Tyler Hansbrough / Markieff Morris
Danny Granger / Paul George / Matt Howard
Vince Carter / George Hill / Lance Stephenson
Darren Collison / AJ Price


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Three Easy Ways to Sneak an SPF Into Your Beauty Routine
Most people who have an aversion to sunscreen just haven't figured out the right way to incorporate it into their beauty routine. Luckily, getting that SPF protection no longer means gooping on a layer of pore-clogging, impossible-to-wear-makeup-over sunscreen every morning. To help out, I've come up with three easy ways to sneak some sun protection into your day.
- Primer: A primer goes on top of your moisturizer to even out skin texture, absorb oil, and hold foundation in place all day long. Smashbox has already released a SPF 15 version of its cult favorite Smashbox Photo Finish Foundation Primer ($42). Or try the Clinique City Block Sheer Oil-Free Daily Face Protector SPF 25 ($16.50), a broad-spectrum sunscreen that can be worn as a light moisturizer or a primer.
- Foundation: Picking a foundation that contains an SPF is an easy way to get sun protection without adding an extra product to your routine. It can be in a form of simply a light-tinted moisturizer, or all the way up to a full-coverage foundation. A product like this LORAC ProtectTint SPF 30 Oil-Free Tinted Moisturizer ($30) gives you light coverage and the benefits of an SPF without clogging your pores. If you prefer slightly more coverage, go for Neutrogena Healthy Skin Liquid Makeup SPF 20 ($11).
- Powder: Powder has gotten a bad rap in the past, but if you choose the right one, you can dust on some SPF protection without looking too makeup-y. I recommend going for a bronzer so you can add a glow to your skin without the sun damage. Try Stila's Sun Bronzing Powder SPF 15 ($28). Or if you prefer powder foundation, check out the SPF 15 mineral powders from Bare Escentuals ($25).
To see two more super-simple ways to add an SPF to your routine,


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"The study of geography is about more than just memorizing places on a map. It's about understanding the complexity of our world." - Barack Obama
In the coming weeks, the University of Louisville geographic information system program will introduce an app geared toward helping the city's immigrant and refugee residents find services in and around the metro area.
The app, a product of an eight-hour hackathon on International GIS Day in November, was created by about 25 people, including students, professors, GIS professionals, UofL staff and Louisville Metro employees... Read more
Nick Potter, an M.S. graduate, is currently working as a GIS Analyst on a project called LinkNYC. The project involves constructing Wi-Fi kiosks across New York City. The kiosks usually replace existing payphones and provide free Wi-Fi- phone calls, and device charging. Nick's job consists of performing spatial analyses to determine how kiosk deployment can effectively balance providing internet access to municipal equity regions, kiosk presence in areas with high advertising value, and construction sites likely to gain fiber access and comply with city regulations. Many of the technical skills Nick uses on a daily basis are products of the Thesis process at Geography & Geosciences.
Faculty Gaughan and Stevens publish paper with colleagues entitled, "Modelling the Changing Population Distribution: Example with the Kenyan Coast, 1962-2015" in the International Journal of Digital Earth.
Dr. Walker publishes "Legal Pluralism, Land Tenure and the Production of "Nomotropic Urban Spaces" in Post-colonial Accra, Ghana" in the Special Issue on The Spatial Dimensions of Informality: Power and Law, Geography Research Forum
Dr. Andrew Day: Modeling urban watershed runoff response for a series of storm events, Louisville, Kentucky – Kentucky Water Resources Research Institute 2016-2017 104b Student Research Enhancement Grant ($4,844).
Ariel Weaver, an M.S. candidate, is currently conducting field work in the Southern African country of Namibia. Her work is funded by a Fulbright Study Research Award and she is focusing on land-use and land-cover dynamics in rural communities as it relates to conservation and development issues.
Masters candidate Adam King is making an impact both locally through his leadership as the current GSC President at University of Louisville and internationally through his thesis research, working with call data records from mobile phones to map seasonal population movements across Bangladesh.
After attending DelphiU in the summer of 2016, MS candidate Nathan Wright is teaching an innovative online section of GEOS 200: The Global Environment.
MS candidate Garrett Seay recently presented his research "Potential for Groundwater Contamination Due to Oil Well Drilling in the Marcum Mill Karst Groundwater Basin, Metcalfe County, KY" at the 2017 Esri Water Conference. He is now working on thesis research modeling urban streams in Louisville with funding from the Kentucky Water Resources Research Institute.


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Gifted and talented children face many challenges. One challenge is being correctly identified. The other is living in a world where their personal traits are often poorly understood. Such challenges put these children at risk for having certain difficulties at home and school. Being gifted may also be misdiagnosed or overlooked.
There is no universally-accepted definition of giftedness, although IQ testing has been among the most commonly used standardized tools to assess ability. Many experts feel that such tests may fail to recognize many truly gifted individuals.
According to the Institute for the Study of Advanced Development, gifted and talented children possess greater than average awareness, perception, and sensitivity. This may be expressed in one or more areas, such as art, music, language, science, or math. Some common traits of gifted and talented children include:
Because of their finely tuned awareness, gifted and talented children tend to experience life differently and more intensely than others. Unfortunately, peers and authorities at school or home often do not understand these differences. Gifted and talented children may experience problems, such as:
The child's intense personal traits and difficulties may be viewed as symptoms of a mental or emotional disorder. Misguided therapy or medication may follow, as the doctor or therapist attempts to suppress or cure the symptoms of giftedness.
Gifted and talented children may be misdiagnosed with other conditions, such as:
Traits such as intensity, impatience, sensitivity, and high energy are common in children with ADHD , as well as in gifted children. Some gifted children do have ADHD, but many do not. They are at a different developmental level than other children. As a result, they may be inattentive and impulsive in certain situations.
Like children with oppositional defiant disorder , gifted children frequently appear strong-willed. However, such behavior may be due to their intensity, sensitivity, and idealism. They do not like to be criticized for their different way of thinking. They may question everything, including the rules and engage in power struggles with authority figures.
Gifted children may have intense mood swings. They notice inconsistencies in society and in the people around them. They can feel different and alienated from others. These traits are often found in children with depression, especially those with bipolar disorder . Symptoms like mood swings, irritability, and difficulties with temper control do not necessarily mean that a gifted child suffers from a mood disorder, but they should likely lead to consultation with an experienced child psychiatrist.
Gifted children like to organize things into complex structures. They tend to be perfectionists and idealists. They can get upset when others do not go along with their ideas, appearing intolerant and bossy. This behavior may be mistaken for obsessive-compulsive disorder or obsessive-compulsive personality disorder .
Highly gifted children often have different ways of interacting socially. Their unusual comments and jokes may be misinterpreted as signs of Asperger's disorder . People with Asperger's disorder may be gifted—especially in certain specific skills—but they do not respond as well as normal children to ordinary social or emotional cues. They may not make friends readily and often prefer to keep to themselves.
Gifted children, on the other hand, often show a great deal of concern for others. If your gifted child gets along well with both adults and children, then a diagnosis of Asperger's disorder is very unlikely.
If you are concerned that your child may be struggling with a mental health concern, make an appointment with a child psychologist who has experience working with gifted and talented children.
In some cases, gifted children may be diagnosed with another condition.
Like all children, gifted children can have hidden learning disabilities. They can be harder to recognize since they may be able to compensate for them. Such disabilities may include auditory processing weaknesses, difficulties with visual perception, writing disabilities, spatial disorientation, dyslexia , and attention deficits.
Gifted and talented children may develop a poor self-image when learning disabilities are present. They tend to dwell on the things they cannot do and may need help in developing a good self-concept. Gifted children with learning disabilities have a great deal of trouble getting needed help in their schools because their academic achievement is usually above grade level despite their disability. Most school systems require a history of academic failure before they will provide remedial services.
Nightmare disorder, sleep terror disorder, and sleepwalking disorder appear to be more common in gifted children. Some gifted children sleep a lot less than other children. Others sleep a lot more. In the presence of unusual sleep patterns, the doctor can help advise you whether a gifted child needs further evaluation for sleep or psychological problems.
Parents and family members may lack information about the traits of gifted children. Such children may appear to be willful, mischievous, or strange. They may be criticized or punished for behaviors that stem from curiosity, intensity, and sensitivity. Power struggles, temper tantrums, and other behavior problems may surface. Effective therapy should involve helping the family understand and cope with the child's intensity.
Gifted and talented children often must overcome many challenges to reach their potential. They frequently need help interacting in the mainstream world, finding supportive environments, and channeling their talents. When gifted and talented children are misdiagnosed and wrongly stigmatized, they cannot get the type of support they need. Families, educators, and doctors need to be better educated about the characteristics and social and emotional needs of gifted and talented children.
GT World for Gifted and Talented Individuals
National Association of Gifted Children
Gifted Canada
Gifted Children's Association of BC
Characteristics of giftedness. Gifted Development Center website. Available at: http://www.gifteddevelopment.com/What_is_Gifted/characgt.htm. Accessed March 13, 2014.
Gifted students. American Academy of Pediatrics Healthy Children website. Available at: http://www.healthychildren.org/English/ages-stages/teen/school/Pages/Gifted-Students.aspx. Updated May 11, 2013. Accessed March 13, 2014.
The gifted underachiever. American Academy of Pediatrics Healthy Children website. Available at: http://www.healthychildren.org/English/ages-stages/gradeschool/school/Pages/The-Gifted-Underachiever.aspx. Updated May 11, 2013. Accessed March 13, 2014.
Webb J, Amend E, Webb N, Goerss J, Beljan P, Olenchak R. Misdiagnosis and dual diagnosis of gifted children. Supporting Emotional Needs of the Gifted website. Available at: http://www.sengifted.org/archives/articles/misdiagnosis-and-dual-diagnosis-of-gifted-children. Accessed March 13, 2014.
Last reviewed March 2014 by Michael Woods, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
Copyright © 2012 EBSCO Publishing All rights reserved.
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text:
But we have to acknowledge that some of the things Donnelly has been saying since he was elected sound encouraging. He wants to extend all the so-called "Bush tax cuts" at least a year, in defiance of President Obama's insistence on ending the one for the wealthiest Americans, and he also wants to reduce spending "in a very significant way," he said in a recent interview.
(Of course Dan Coats, Indiana's senior senator, is thinking along the same lines, but that's not exactly startling for a conservative Republican).
Before it can even begin to deal with the country's long-term economic problems, Congress has to avoid the fiscal cliff looming at the end of the year that will bring $600 billion in automatic tax increases and spending cuts (largely to the military) if something isn't done. The crisis was brought on by Congress' earlier decision to put in automatic budget triggers in order to put off a decision. Congress in essence decided to hold itself hostage, and judgment day is here.
If the triggers kick in, an already shaky economy will likely stall again, sending America back for another round of recession. But care has to be taken in how the triggers are avoided. Letting taxes go up for any group is dangerous in tough economic times, but punishing those who create jobs – i.e. all the small-business owners among those "richest Americans" – is just plain stupid.
Senators Donnelly and Coats seem to understand this. Obama clearly does not.
It's probably too much to ask for Congress to come up with a permanent "fiscal cliff" solution during a lame-duck session. Donnelly's idea for a one-year extension is a good one – the best to hope for is a temporary fix that doesn't cause any harm and also sets the stage for addressing our systemic economic problems, which must include serious tax reform.
Considering that, Coats says we should start eliminating deductions and loopholes so tax rates can be lowered, and Donnelly mentions the need for lower corporate tax rates.
All of that is encouraging, too. Hang in there, guys.


text:
Hi Tom
I fingered it out from a couple of code comments that I had to change a parameter in the AIPersonalize routine for a 6221 card and I am now reading data. Yay!
I still need to figure out how to compile and link "chipobjects", dma and rdhddk_rtx code in a Visual Studios Net 2003 project so that I can utilize these functions in my 6221 driver running under RTX and a proprietary API. Any tips or advice would be appreciated.
02-15-2008 11:23 AM - edited 02-15-2008 11:24 AM
Hi Floyd-
The biggest thing you would need would be to define all of the virtual paths for the various source and include files. You might also need to add preprocessor #defines for a couple of things, notably kLittleEndian or kBigEndian. All of these settings can be made in the Visual Studio project properties window (right-click on the project name in project explorer).
I don't have an RTX environment up to test on, so I just built a project for Windows (using NI VISA) and got it compiling. You should be able to use most of the settings here to help get your RTX build working. I just noticed that you're using VS2003 and I created mine in VS2005, so you might want to download one of the "free" Visual Studio 2005 express editions to view this.
My project was created with all files residing in C:\mhddk. The additional include directory setings and preprocessor defines are made as shown here:
Since you're using the entirely source-based RTX O/S interface from the MHDDK you shouldn't need to include any additional libraries for the linker. FYI, I had to include visa32.lib for mine because I was using NI-VISA for Windows.
Hi Floyd-
tMSeries.h defines some helpful enums (that we chose, for some reason, to not use in that example ), for example tPFI0_Output_Select() which defines PFI_DO as 0x10. The format of the PFI_Output_Select_1 register is as follows:
bits 0-4: PFI0 select
bits 5-9: PFI1 select
bits 10-14: PFI2 select
bit 15: reserved
with the same pattern repeating for PFI_Output_Select_N where N is a number between 1 and 5 and the PFI bitfields increase with the same pattern as PFI_Output_Select_1. PFI_Output_Select_6 contains the selection for PFI15 in bits 0-4 and the rest of the bitfields are reserved.
The values written to those registers by dioex2 correspond to setting the lowest PFIn lines to PFI_DO (i.e. output) and the upper PFIn lines to "default" (i.e. input). The setting for IO_Bidirection_Pin sets the PFI lines to input or output where bits 15-0 correspond to PFI15-PFI0, respectively. As you might guess, a value of '1' corresponds to output and a value of '0' corresponds to input.
Hello Tom,
I am solving a similar issue here. When I was trying to perform "make" I have received an error saying, that it can not open the file "visa.h". I really don't have this file, when I check win-visa.mak -> path "C:/VXIPNP/WinNT/include". Can you give me any advice, how could I create this dir structure or any other solution?
Thank you in advance for your reply.
Hi Rasto,
Depending on the development support selections you made when you installed NI-VISA, "visa.h" and "visa.lib" may be in a couple of places. A couple of common locations are as follows:
For visa.h:
C:\Program Files\National Instruments\Shared\CVI\include\visa.h
C:\Program Files\IVI Foundation\VISA\WinNT\include\visa.h
For visa.lib
C:\Program Files\National Instruments\Shared\CVI\bin\msvc
C:\Program Files\IVI Foundation\VISA\WinNT\lib\msc
You could also run a search on your harddrive for the file. Then you can copy it and any dependencies to whatever directory you desire.
John M
Hello John,
thank you very much for your reply. I have found all the needed files in path proposed by you and changed it in "win-visa.mak". After that, compiling was running well. Then there were some changes in "ai.h" to configure measurement and everything is running well.
Thank you once again,