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Wieters' walk-off grand slam lifts O's in 10th
BALTIMORE -- After rounding third and heading toward a mob of teammates waiting for him at home plate, Orioles catcher Matt Wieters gleefully flicked off his helmet and jumped right into the celebration.
Wieters is not the type of player to show much emotion, but even he could not hide his excitement after hitting a walk-off grand slam in the 10th to lead Baltimore to a 10-6 victory over Tampa Bay on Thursday night.
The victory clinched the second series win over the Rays this season. The teams combined for seven home runs. It was the first walk-off grand slam by the Orioles since Harold Baines in 1999.
"I felt it was going to go, but more importantly, I knew it was going to get the run, whether or not it went out," Wieters said. "I knew the game was going to be over. That's a good feeling, and now we'll move forward to tomorrow."
The Orioles were also able to overcome a shaky outing by starter Miguel Gonzalez, who allowed two of his three home runs in the first inning. Gonzalez did not get a decision after allowing four earned runs on eight hits with one strikeout and two walks over 5 2/3 innings.
Tampa Bay starter David Price also had an unsteady outing. He allowed five runs on eight hits with six strikeouts and no walks through six-plus innings.
The Orioles trailed, 5-4, in the seventh when J.J. Hardy led off with a double that ended Price's night. Jake McGee entered and immediately gave up a two-run homer to Steve Pearce, who snapped out of an 0-for-15 skid to start the season.
"I've been swinging good, having good at-bats, just wasn't able to find a hole," Pearce said. "I just told him that to try and psych us both up, and fortunately I was able to get something going for myself and for the team."
Prior to that home run, the Orioles' designated hitters were 3-for-49 with one homer and one RBI.
The Rays, however, responded in the eighth, tying the game on a homer by James Loney off Darren O'Day. It was the first home run O'Day had allowed in eight appearances.
Orioles reliever Jim Johnson pitched a scoreless ninth, helped by Wieters' throwing out Desmond Jennings trying to steal second with one out. Wieters has now thrown out seven of nine runners attempting to steal this season.
The Orioles broke the deadlock in the 10th, when Nick Markakis led off with a single and Manny Machado reached on a bunt up the first-base line. Adam Jones hit another long single to load the bases. The runners were all moving on Jones' hit, and Tampa Bay manager Joe Maddon argued Jones did not re-touch second base on the way back to first.
The umpires overruled Maddon, and that set up Wieters' heroics off right-handed reliever Brandon Gomes.
"I just have to do my job there," Gomes said. "I haven't seen the pitch to Jones, but I'm assuming that slider was left up. Then I tried to go back-door slider to Wieters, and it caught way too much of the plate. So, you're going to get hurt when you're facing the middle of that lineup."
Asked if Gomes' approach would have been different had Jones been ruled out, opening up first base, Gomes said: "It could have. But I'm not going to play that game. I just didn't execute the pitches I needed to; that's really all it is."
After having just five home runs on the season entering the series, Tampa Bay had nine round-trippers against the Orioles over the three days.
"I just wanted to put it down somewhere, get Nicky over," Machado said. "I got a hit out of it. It was a perfect bunt. I couldn't have placed it better. I've been working on bunting, not really sacrificing. It's just something you can't practice. It's in the heat of the moment. Adrenaline pumping. You've just got to lay it down there."
For the second time in the three-game series, Jennings led off the game with a home run to left center. It was the sixth leadoff homer of his career. Two batters later, Evan Longoria homered to almost exactly the same spot for a 2-0 lead.
Orioles starters allowed first-inning home runs in all three games of the series after not having allowed a first-inning homer in their opening 12 games. Gonzalez struggled in the second as well, loading the bases on singles by Loney and Jose Molina before hitting Yunel Escobar. A sacrifice fly by Jennings increased the Rays' lead to 3-0.
The Orioles tied the game in the second when Wieters opened with a double and scored on a single by Chris Davis. Nolan Reimold then hit a two-run homer with two outs that just cleared the deepest part of the center-field wall.
Tampa Bay regained the lead in the third after a throwing error by Hardy botched a double play that would have ended the inning. The Orioles again tied the game in the fifth on a two-out double by Machado and could have taken the lead, but Markakis hesitated rounding third and was tagged out in a rundown.
The Rays made them pay an inning later as Molina provided a 5-4 lead with his first home run this season. Singles by Escobar and Jennings then ended Gonzalez's night.
Gonzalez was the only Orioles starter to pitch more than five innings in the series. Jake Arrieta got the win Wednesday night, allowing one run on 112 pitches in five innings, while Chris Tillman took the loss Thursday after giving up four runs in five innings.
"It was a good game for us." Orioles manager Buck Showalter said. "To beat them in the series at home, and we knew it was going to be a really tough challenge with Price out there. It was a good win, to be down, 3-0, there with Price and being able to figure out a way. There was a lot of frustration funneled in the right direction after we got down. I'd like for them to get a good night's sleep and feel good about themselves, and we've got a challenge getting ready for the Dodgers."
Todd Karpovich is a contributor to MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.


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Get an overview of this hotelRiverfront hotel in Tampa's business district
Popular property highlights
With a stay at Sheraton Tampa Riverwalk Hotel, you'll be centrally located in Tampa, steps from Florida Museum of Photographic Arts and minutes from Curtis Hixon Waterfront Park.
This hotel is within close proximity of Tampa Museum of Art and Glazer Children's Museum.
Make yourself at home in one of the 277 air-conditioned rooms featuring flat-screen televisions. Your room comes with a pillowtop bed. Complimentary wired and wireless Internet access keeps you connected, and cable programming provides entertainment. Private bathrooms with shower/tub combinations feature complimentary toiletries and hair dryers.
Don't miss out on recreational opportunities including an outdoor pool and a fitness center. Additional features at this hotel include complimentary wireless Internet access, concierge services, and gift shops/newsstands. Guests can get around on the complimentary shuttle, which operates within 3 mi.
Satisfy your appetite at the hotel's restaurant, which serves breakfast, lunch, and dinner. Dining is also available at a coffee shop/café, and room service (during limited hours) is provided. Quench your thirst with your favorite drink at a bar/lounge.
Featured amenities include a business center, limo/town car service, and express check-in. Planning an event in Tampa? This hotel has 14000 square feet (1301 square meters) of space consisting of a conference center and meeting rooms. A cruise ship terminal shuttle is provided at no charge.Information missing or incorrect? Tell us!Opens in a new window
Sheraton Tampa Riverwalk Hotel
Hotel Amenities
Hotel Amenities
Located 3 blocks from Tampa Art Museum and 4 blocks from Tampa Convention Center.
Additional complimentary amenities include an area shuttle, high-speed wireless Internet access in the lobby and at "The Link@Sheraton"; and access to a computer, fax machine, and printer.
Guests enjoy an outdoor heated pool. The fitness center includes an exercycle, a stair machine, a treadmill, and free weights. The restaurant offers panoramic views of the river. A 200-foot private boat dock is available for charters and docking.
This Tampa hotel offers 14,000 square feet of meeting space with theater-style seating for up to 500, and a conference center. Audiovisual equipment and catering services are offered.
- Outdoor pool
- Fitness facilities
- Restaurant
- Coffee shop or café
- Breakfast available (surcharge)
- Bar/lounge
- Airport transportation (surcharge)
- Limo or Town Car service available
- Conference space
- Meeting rooms 11
- Multilingual staff
- Safe-deposit box at front desk
- 24-hour front desk
- Porter/bellhop
- Express check-out
- Express check-in
- Total number of rooms - 277
- Gift shops or newsstand
- ATM/banking
- Laundry facilities
- Dry cleaning/laundry service
- Coffee/tea in common areas
- Elevator/lift
- Number of floors - 7
- Wedding services
- Free WiFi
- Computer station
- Rooftop terrace
- Business center
- Concierge services
- Valet parking (surcharge)
- Luggage storage
- Conference center
- Conference space size (meters) - 1301
- Free area shuttle
- Smoke-free property
- Free newspapers in lobby
- Free cruise terminal shuttle
- Free shopping center shuttle
- Number of meeting rooms - 7
- Conference space size (feet) - 14000
- Television in common areas
Family Friendly Amenities
- Family Hotel
- Outdoor pool
- Free Wi-Fi
- Area shuttle (complimentary)
- Laundry facilities
- Refrigerator (on request)
- Microwave (on request)
Available in all rooms: Free WiFi , Free wired Internet
Available in some public areas: Free WiFi
Valet parking (surcharge)
Room Amenities
- Premium TV channels
- Pay movies
- Hypo-allergenic bedding available
- Premium bedding
- Room service (limited hours)
- Free newspaper
- In-room climate control (air conditioning)
- Air conditioning
- Blackout drapes/curtains
- Phone
- Coffee/tea maker
- Refrigerator (on request)
- Free bottled water
- Microwave (on request)
- Shower/tub combination
- Free toiletries
- Hair dryer
- Iron/ironing board
- Desk
- Cable TV service
- In-room safe
- Daily housekeeping
- Private bathroom
- Connecting/adjoining rooms available
- Flat-panel TV
- Free WiFi
- Free wired Internet
- Pillowtop mattress
Where to Eat
Ashley Street Grille - Floor-to-ceiling windows overlook the scenic Hillsborough River. Breakfast and lunch is casual; dinner is elegant with twinkling city lights as a backdrop. Menu favorites include salads, tuna, penne pasta, seafood, and beef dishes.
Ashley Street Grille Lounge - Open early afternoon until late night.
Nearby Things to Do
This hotel's outdoor splash pool overlooks the Hillsborough River. The fitness center includes a sauna, exercycle, stair machine, and treadmill.
Located two blocks from the hotel, Bayshore Boulevard's sidewalk extends seven miles and is great for jogging. The local YMCA is within four blocks of the hotel. An 18-hole golf course is available eight miles away at the University of South Florida.
The recreational activities listed below are available either on site or near the hotel; fees may apply.
- Golfing nearby
- Snorkeling nearby
- Sailing nearby
- Water skiing nearby
- Personal motorized watercraft on site
- Hiking/biking trails nearby
- Bicycle rentals nearby
If you have requests for specific accessibility needs, please note them at check-out when you book your room.
- In-room accessibility
- Roll-in shower
Hotel Policies
Check-in time starts at 4 PM
Check-in time ends at midnight
Minimum check-in age is 21
Special check-in instructions:
Check-out time is 11 AM
Payment types
Children and extra beds
- Children are welcome.
- Kids stay free! Children 17 years old and younger stay free when using existing bedding.
- Rollaway/extra beds are not available.
- Cribs (infant beds) are not available.
- Pets not allowed
You need to know
Extra-person charges may apply and vary depending on property policy.
- Minimum Spring Break check-in age is 21 years old.
- Resort fee
- Pool access
- Fitness center access
- Internet access
Optional extras
- Breakfast fee: between USD 14 and USD 20 per person (approximately)
- Airport shuttle fee: USD 10 per person
- Valet parking fee: USD 24.00 per night (in/out privileges)
- Refrigerator fee: USD 20.00 per night
- In-room microwave fee: USD 10.00 per night
Hotel Name
- Hotel Sheraton Tampa
- Riverwalk Hotel Tampa
- Riverwalk Sheraton Tampa
- Sheraton Hotel Tampa
- Sheraton Hotel Tampa Riverwalk
- Sheraton Riverwalk
- Sheraton Riverwalk Hotel
- Sheraton Riverwalk Tampa
- Sheraton Tampa Riverwalk
- Sheraton Tampa Riverwalk Hotel
- Tampa Sheraton
- Sheraton Tampa
We should mention
A resort fee is included in the total price displayed. Children 17 years old and younger stay free when occupying the parent or guardian's room, using existing bedding. The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation.

subset: commoncrawl


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Dogs Looking Goofy | Pictures
Silly Dog! Cute Pictures of Goofy Pups
Silly Dog! Cute Pictures of Goofy Pups
Prepare for some serious snickering while checking out this bunch of pups that were snapped when looking their goofiest. We all have those moments when we get caught doing something silly, making these pictures even more laughable. From sleeping dogs in uncomfortable positions to big dogs thinking they fit in small spaces, here's a seriously foolish collection of pups caught being silly.
Source: Flickr users Tc Morgan, Instagram user nathan_alalouf, Flickr user TheGiantVermin, and Instagram user sim_rat
0previous images
-21more images


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Wouldn't it be grand if serious progress was made on the regional desalination project while most of us were distracted by the holidays? We have heard, and you have read, quite little on the subject for some time. Could it be that no news really is good news?
Sorry. Nothing of substance to report here except for the rumor that all those water experts and their lawyers mediating and arbitrating and otherwise talking behind closed doors for several months may be nearing the end of their discussions. They may soon be ready to start talking about trying to actually revive the project.
Put another way, it may be true that Monterey County and Cal Am and the Marina Coast Water District and who knows who else may have found a way to continue without a bunch of lawsuits over their roles in letting the project become tangled by conflicts of interest, jarring cost estimates and other complications.
In case you've forgotten, the project was chugging along with some deliberateness until last spring. The hope was we could show state environmental regulators that we are serious about creating an additional water supply and it won't be necessary to jar us into action by curtailing our access to water from the embattled Carmel River.
Then, word got out that Steve Collins, one of the county officials heavily involved in the project, was being paid on the side by the project manager. Screech! A delicate process suddenly looked hopeless. If it was a car, it would have left some long skid marks. Then a judge ruled that the Marina Coast district and not the state Public Utilities Commission should be the lead agency on the desalination venture, and that the environmental impact report needs to be redone.
Some believe all that is left is last rites, but others in positions of influence maintain the project is salvagable. Among their suggested rescuscitation steps are possible downsizing, combining desal with other ventures and restructuring the governing structure. As to the legal ruling, they say the smart thing is to go along with it rather than fight it. Appeals could take years that we simply don't have.
Largely because of the threatened Carmel River cutoff, we believe it is critical for the community to move forward on several fronts, including a significant desalination plant. We also maintain our hope that a new management structure will be developed that provides the bill-paying public with more than token say over the operation.
It is not the perfect project. Far from it. But the only real alternative for now would be to turn off the pumps along the Carmel River, which would prove devastating to the local economy. Better an imperfect project than economic meltdown.
In the past, we have encouraged a committee of Peninsula mayors to work toward creating a joint-powers agency that could take on responsibility for the project, but we have heard little about that of late. Another possibility worth pursuing would be to make the Monterey Peninsula Water Management District an official participant, replacing Monterey County, a most reluctant partner.
While critics of the water management district would surely resurrect old arguments about how the agency has done little over the years to solve the Peninsula's water shortage, district officials have come to understand the current realities as well as anyone. The district's board chairman this year is Dave Potter, the same Dave Potter who sits on the county Board of Supervisors. He may not have the answers but he certainly knows what questions to ask.
The district would provide much better representation for Peninsula residents, who, as it stands, are likely to be hit with oversized water bills despite having no voice in the process. Also weighing in the water district's favor is that it is directly involved in other water projects that should and could be used to supplement production from a desal plant.
If it is true that the closed-door legalistics are coming to an end, we're about to return to an intensely political stage of this process. Rather than wasting precious time fighting old fights, project principles and community leaders should be looking for areas of agreement and preparing to move the project ahead one way or another.


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DETROIT - It's the money mistake thousands of Michigan homeowners have probably made when selling their homes.
Michigan has something called the State Real Estate Transfer Tax. The seller pays .75 percent of the sales price when the deal closes. Ruth to the Rescue spoke to a Macomb County resident who was surprised to learn he paid the tax, when he was actually exempt.
"Initially, I was definitely disappointed that there was a mistake that I overpaid," the homeowner, Brian, told Ruth to the Rescue.
Mistakes Uncovered
Attorneys at 1-800-LAW-FIRM contacted Brian after public records showed he paid that tax. The law firm's CEO Ari Kresch says it's helping hundreds of people in similar situations.
"This tax is calculated and nobody pays attention to the exemption probably because they were never trained, they don't care, it's not their money," Ari Kresch told Ruth to the Rescue.
He says it's probably nothing that happens on purpose, but it something that falls through the cracks during the sale.
While there are other reasons for homeowners to be exempt, Kresch says homeowners like Brian are exempt when they sell their homes for less than they paid for it. Brian says he paid about $307,000 for his home, and later sold it for $250,000. He received a refund of around $1,000. The firm did charge a contingency fee for helping Brian.
"This is a widespread practice, people need to know about it," said Ari Kresch. "The state of Michigan has been very very cooperative in refunding our clients' money. It wasn't their fault."
Get Refunds Online
Michigan's Department of Treasury agrees with that assessment, and also points out, you don't need an attorney or third party to claim any refund. There is information about who qualifies for exemptions from the real estate transfer tax. There is also a form to start the process of claiming that refund. If the form and the proper documentation is submitted, you will receive the refund you're due.
The homeowner we spoke to says the whole experience taught him to ask questions about every expense when selling or buying a home.
"Do all the homework myself, make sure that everybody that is working for me, is indeed working for me," Brian told Ruth to the Rescue.
Here's the link to the Michigan Treasury Department website for more information.
Copyright 2012 by ClickOnDetroit.com. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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Dundjinni is a sophisticated cartography and authoring application aimed at the PRPG community. Dundjinni includes content from various industry leaders, such as Reaper Miniatures, Monte Cook, and Dork Tower.


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Hello Sir,
I have two signals of different frequencies but i want to take the FFT power spectrum of both signals at same graph . So for that case i take the FFT power spectrum of both signal indivisualy and after this build the array. so i got the one graph and all the components in same graph. Now
The problem is that in that graph i want to extract the magnitudes at each frequency, but when i extract the information from final graph it will be the " 1D array of Cluster of 3 Elements" so its information is saprate for these two signal. but i want to tale the magnitude at each frequency , how can i got this sir . Please Help me
My first question:
You say you are combining the outputs from the two FFT's; how exactly are you doing this?
The first thing you have to watch out for is that your sampling frequency and number of samples for each FFT is identical. Then you "combine" the signals by making the signal array portion of the FFT's waveform output into a 2 dimensional array, as opposed to a single dimensional array. Put the single dimensional information for each of the FFT's into its own array in the 2 dimensional array of the waveform cluster, then feed it to your graph. It will show each FFT as a separate trace on the graph.
I am doing this in an application with 8 simulaneous FFT's, so I know it works.
Clear as mud?, give it a try, good luck.
Sir it works thanks but there is one new problem is that wahen i am going to extract the magnitude for every frequency it is also works, but my question is that if my frequency is in floating point then how can i extract magnitude for that frequency. i mean i extracted the magnitude for every frequency component starting from 0 to 1...2..3...4.............so on (Frequency ) but if my frwquency id 2.3Hz so how can i do this.i am sending you my VI also
The way to get more resolution in your X axis is to increase the number of samples in your data set. Not the sampling frequency, but the actual number of samples you take in each data set.
Have fun


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Do you Moo?
I wanted to talk a minute about Moo.com because I have LOVED everything I have ordered from them. I rarely talk about products on here but, I get so many comments about these products whether it's something for my blog or for my personal life.
I was first introduced to Moo by Foodbuzz. Every featured publisher gets a free set of minicards from Moo when they sign up. I got my minicards with my blog name and email address with just some stock photos on the other side. I remember being instantly impressed by the quality of the cards. They are seriously THICK and have a great satin matte finish.
Since then, I decided I wanted business cards with photos that are from my blog. I love that you can upload up to 50 photos for your 50 business cards. I usually go with 10-12 photos per set. And they come in a nice black box. I keep mine in my purse at all times so I always have my cards handy.
And check this out. This is a new feature since the last time I ordered business cards. Now you can get a photo/logo printed on the back of your business card. It takes up the top third or so for the card. I put my blog header up there since I don't really have a logo and then included my key info under the header.
I've also ordered their postcards. I have postcards for my blog that I include in anything I ship for my blog. So for giveaways that I host or packages I send overseas for Operation Baking Gals, I write a little note on the back and throw one in the box. I have also used the postcards for party invitations and my nephew's birth announcement (with nothing on the back) as well. The postcards are thick like card stock with a glossy finish.
When I ran out of business cards and needed to order more, I contacted Moo.com to see if they would give me some for free (hey, it's worth asking!). They said they couldn't, but did offer me 30% off of three products. Since I was already planning to order more business cards and postcards I decided to try something new. I went with the sticker book. How fun is this little guy! Now I have little Beantown Baker stickers. I'm still not sure what I'll do with them, but I'm sure I'll come up with something.
So if you're in need of anything printed, definitely check out Moo.com.
**Disclaimer, I am not being paid for the post. I was offered 30% off to try 3 products from Moo.
16 Responses to "Do you Moo?"
I was told about Moo.com too recently. I checked out their site and it's really cool! I am probably going to order soon. 🙂
I've never heard of Moo.com…will have to check them out!
i've been seeing a lot about moo.com lately.
i've heard their products are great!
i've been wanting to get postcard of my b&b made for my gift shoppe!
anyway of getting a little discount for your readers … a wise woman once told me it doesn't hurt to ask. 😉
I think your new business cards are great. This is the reminder I needed to order some new ones myself. And the stickers are adorable!
I love Moo! I'm sure it's changed a lot since I first received my cards from FB about a little over 3 years ago, but I'm ready to order some more with MY photos! Yay! Thanks for the reminder! Your cards look GREAT!
I love Moo! They have a moo.co.uk so us non US people don't have to feel left out. My mini cards are really cute and people are usually pretty impressed! They came in a cute white box.
I love my mini Moo cards!
Great rec! They look great. I didn't get any cards from FB…!!!
What an awesome website! I've never heard of it, thanks for sharing. 🙂 Btw, I looove the sticker book, so cute!
i think i signed up too late for foodbuzz because I got the shaft! You business cards are some of the best in the blog business. bright, colorful, savy. way to go.
Wow, these are so great! I've never heard of this website, I'll have to check it out!
The products look great. Use the stickers as labels for packaging when shipping your products – or sealing envelopes.
I love Moo as well – they're expensive but you can tell the difference in quality!
Would love to see what you do with those stickers – they do look super fun! 🙂
Good point Michael. I asked and they said they couldn't offer a discount to my readers. Sorry about that.
I love your business cards! This site is great, VistaPrint better watch out!
If your readers want 30% discount on their first order of MOO cards here is a code valid until 11:59pm (GMT) 31st January 2011: Code – SPYZQ5
Valid for first time users only. Shipping is not included in the 30% discount.


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Moderators: OGRE Team, OgreDotNet Moderators
adjohn wrote:Just want to let everyone know that there has been an update of OgreDotNet. It has been moved to newer versions of bindings and such. You can find the updated project at http://code.google.com/p/ogredotnet/. It currently is working and confirmed in OS X and Linux platforms at the moment.
You can reach us on IRC (freenode) #ogredotnet channel
$ make
[ 50%] Swig source
Unable to open file OgreNet/build/StringUtil.cs: No such file or directory
make[2]: *** [OgreNet/OgreBindingsCSHARP_wrap.cxx] Error 1
make[1]: *** [CMakeFiles/OgreBindings.dir/all] Error 2
make: *** [all] Error 2
Users browsing this forum: No registered users and 1 guest


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Coming off a playoff appearance last year, the Red Bluff Lady Spartans basketball team just got a little bit scarier.
Red Bluff finished 15- 11 last season and fell to Pleasant Valley in the Northern Section Division II semifinals.
?This is not only the most athletic team, but the best shooting team we've had as far as just pure shooters,? said Spartans coach Kathy Brandt, who is in her fourth season.
?So we can penetrate and kick and actually hit threes, which we haven't been able to do.?
That shooting ability from guards such as Chelsey Bushnell, Emily Gallagher, Daisy Brose, Maggie Hansen and Brittany Clatty give the team more flexibility to find 6- foot-2 freshman center Payten McKerras in the post, which, Brandt said, is the first time she's had a player that tall.
What's more, she said, is that McKerras can ?run like a deer? in addition to being a great shot blocker.
The team won't lose mobility with McKerras on the floor, Brandt said, adding that her wingspan will be a benefit at the top of the key when the team plays zone defense.
Red Bluff's seniors, which include four returners in guards Taylor Wood, Alex Dahnke, Lily Brose and forward Jessica Macdonald will lead the team, Brandt said.
And the Spartans will also get a boost from its stable of players coming up from a successful junior varsity squad.
?This junior class comes with an impressive record of, I believe, 43-3,? Brandt said.
?So they're very used to winning and going into the league we're going into you have to have that mentality.?
Red Bluff finds itself in a new division and league, where their newfound athleticism and shooting ability will be put to the test.
Gone are lowly Oroville, Lassen and Las Plumas teams. The Lady Spartans, now in Division III and in the Sac River League, will face the likes of West Valley, Foothill and Enterprise.
?I feel every league game will be a dogfight,? Brandt said. ?The other schools ... are all really talented. So every night we're going to have to be ready to play and play at a high level.?
The Lady Spartans will open their season with a trip to Anderson on Thursday for the Tip-Off Classic.
Their first game is scheduled for 5:30 p.m. against Trinity.
?We should be fun to watch,? Brandt said. ?That's the goal. We should be fun to watch, we should be deep and hopefully we'll win some ballgames along the way.?
Sports Editor Andre Byik can be reached at 527-2151, ext. 111 or at email@example.com.
Follow him on Twitter: @TehamaSports


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A KIND-hearted woman has donated four pieces of equipment to the stroke unit at Fairfield Hospital in memory of her late grandmother.
Joanne Wells ran the Manchester Marathon and raised nearly £500 to buy four portable nebulisers for the unit where her grandmother Maureen Black died aged 83 in March.
Mrs Wells, aged 40, knew the unit did not have enough machines while her grandmother was in hospital.
Mrs Wells, of Bowlee Close, Unsworth, said: "Rather than raise some money and give it to a particular ward, I wanted to be able purchase something for the hospital.
"I was running the marathon anyway, but I then decided to do it in memory of my gran.
"We are missing her. She was a real matriarch and head of the family. It will be great to have something like this."
Mrs Black lived in Crumpsall after moving from Ireland, and had seven children, five grandchildren and four great-grandchildren, who knew her as Nana Maureen.
Mrs Wells said her grandmother was very self-sufficient, even at the end of her life. She said: "She was still quite fit for 83, and lived on her own so the stroke itself was a shock.
"She was told she didn't have very long at first, but she lasted for a few weeks. She never lost her sense of humour.
"She was fiercely independent, and when she was in the hospital she asked me to record the Winter Olympics so she would not miss it."
Nebulisers are electrical machines that turn liquid medicine into a fine mist, which can be easily breathed into the lungs.
Denise Knowles, ward manager of the stroke unit, said: "We discussed with Joanne what the money might be used for and agreed to buy some nebulisers.
"We really appreciate what Joanne has done for the stroke unit and for her kind donation."


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What a difference a few hours can make! Jessica Simpson, in London to see little sis Ashlee's debut in Chicago, rolled off the airplane at Heathrow bright-eyed and fresh-faced (left). And after a brief stop at her hotel, she emerged for a night on the town with a full face of makeup, including dark smoky eyes and glossed pink lips. We have to admit that when it comes to Jessica's beautiful face, we think less is more. Do you agree? Tell us: Which look do you prefer on Jessica, natural or glam?
To see more of Jessica click here and for more of our favorite beauty products and looks click here
Photo Credit:
Photo: XPOSURE/RAMEY (2)


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Groene at the Legislature: Teacher absences, substitutes
Mail: Southern statues symbolize suppression
More opinion
Senate: Vote no on Graham-Cassidy health care plan
Fall: Good time to spray musk thistle in rosette stage
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Deputies went to a motel south of I-80 in North Platte Wednesday, looking for Cara M. Harder, 27, of Grand Island. They found her, and much more.
Harder came to the door of the motel room and was arrested there. She wanted some of her things from the room and when she went to get them, she allowed deputies inside, where they saw drugs (suspected methamphetamine) and drug paraphernalia.
They also found Terry A. Houchin, 29, in the room and arrested him.
Houchin is charged with possession of a controlled substance and drug paraphernalia. Harder was charged with possession of a controlled substance, paraphernalia and possession of stolen property.
So far, in the course of this major investigation into burglaries and drugs in Lincoln County, deputies have seized eight cars, a Harley Davidson and a large amount of money, according to the sheriff's office.
The investigation is continuing.
Additional charges may follow for Harder and Houchin, the sheriff's office said.
Previously, Cody Jolliffe and Jacob Moser were charged Saturday with the burglary. A third man, Ryan Walsh, was charged Monday.
On Thursday, bond was set at $10,000 for both Harder and Houchin.
Houchin also faces previous Lincoln County charges in a March burglary and possession of hashish in January. He was out of jail on bond when he was arrested, awaiting his day in court.
With the arrest, Houchin's previous bonds have been reinstated and his cumulative bonds now total about $50,000, according to sheriffs records.
Harder had little to say at her arraignment. She asked for a public defender.
Also, deputies arrested Jason E. Sullivan, 29, on Thursday, as part of the investigation. Sullivan is in jail, charged with possession of amphetamine with intent to deliver and theft by receiving stolen property.
His bond is set at $100,000.
For more details about recent burglaries and drugs in Lincoln County, pick up a copy of the North Platte Bulletin's print edition, on sale now.
Flatrock Publishing, Inc.
1300 E 4th St., Suite F
North Platte, NE 69101


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Researchers at a recent ear, nose and throat medical convention reported new findings from an 18-year hearing study that evaluated the diets of male health professionals. More than 26,000 men, aged 40 to 75, started the study with normal hearing. Over the course of 18 years of follow-up, about one in seven developed hearing loss. In men over the age of 60, those who consumed about 800 mcg of total folates per day, including folic acid, were 21 percent less likely to have lost hearing compared to those who got the least folate.
In a related hearing study, over 700 men and women, aged 50 to 70, took 800 mcg of folic acid per day or a placebo. After three years, both groups had lost some low-frequency hearing, but the folic acid group had about half the hearing loss as the placebo group.


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The Hershey Company: Pause to Support a Cause
June 9, 2011
Ed Martin, director, marketing excellence and corporate social responsibility insights at The Hershey Company, discussed the evolution of the Pause to Support a Cause program and how this innovative method of compensating research participants helps decrease research costs, shorten fielding times, heighten response rates, and encourage more active year-round participation in market feedback, engagement, and listening programs.
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Families had a tea party with a pair of sheep to celebrate the reinstatement of the ha-ha at Hillworth Park in Devizes.
The walled trench was designed to separate grazing animals from gardens without spoiling the view and dates from the 18th century.
Devizes Town Council bought Hillworth Park after the Second World War but by then the ha-ha had been lost and only the top stones of the wall were visible.
After the refurbishment of Hillworth Park two years ago, the Heritage Lottery Fund awarded £50,000 for the restoration of the ha-ha.
To celebrate the town council held a tea party while two sheep from Rowdefield Farm were contained on one side of the ha-ha, to show how it was used.
Four members of the orchestra Southern Sinfonia played music and about 150 people attended.
Carole Berry, direct services manager at the town council, said: "A lot of people said how lovely the ha-ha was. A lot of people didn't know what a ha-ha was so we explained its purpose."


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I see a lot of people here talking about either co-washing or no shampoo. As a guy the no shampoo is a hard sell. I tend to go with shampoos meant to restore thickness because us guys are hardwired to think we'll lose our hair. I've thinned some at 40 but I also had a lot to lose and still have a lot as it is. However, I'm glad that seven years ago I came around to enjoying having curls. Maybe it took the reality of seeing other guy friends and acquaintances lose theirs.
"curls aren't just for girls."


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The Osseo Police Department is now accepting applications for Volunteer Police Reserve Officers to assist with a variety of tasks such as traffic control, crowd control, assistance at accident scenes, fire, natural disasters, general patrol duties and assisting licensed Police Officers as needed.
New Reserve Officers will attend the Hennepin County Sheriff's Office Reserve School and will complete a mandatory in-house field training program to help familiarize themselves with the equipment, geography and procedures of the Osseo Police Department. Other training includes defensive tactics, firearms, Taser, personal chemical spray and more.
Reserve Officers do not carry firearms.
To be eligible, a person must be 18 years of age or older, have a high school diploma or equivalent, live within the city of Osseo or have a 20-minute response time to the city, a valid Minnesota driver's license with a good driving record and be able to pass a background investigation.
For a complete job description and to apply, visit the city of Osseo's website at discoverosseo.com to download the necessary materials. Applications can also be picked up at the Osseo Police Department or by calling 763-424-5444.
The application deadline is Monday, Oct. 15, at 4 p.m. Completed applications need to be submitted to the Osseo Police Department, Attn: Reserve Coordinator, 415 Central Ave., Osseo, MN 55369.


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So I've finally decided to start playing competitively. There's a tournament coming up at my home course in May and I'm going to enter. Understand, I've only pretty much played casually...I've only played league twice, and outside of that, I play with a couple friends (talented friends, but still friends.) I play about once a week...I'll need some practice leading up to the tourney. As soon as it warms up in the mornings, I'm going to be playing a couple times a week.
I'm competitive in nature, so I want to play in the Advanced division. I know that my scores in casual rounds are good enough for Advanced. I don't care if I get beat bad, I'd just like to play with guys that know what they're doing and learn from the experience. But there is an intermediate division, and I'm kind of thinking that I should be playing intermediate since it's my first tourney...anything could happen out there, who knows what kind of dumb things I could end up doing, and that kind of stuff might be better suited for the Intermediate level...
I typically play better under pressure in sports, but I could just as easily see myself choking under the pressure when putting. It's a long and very wooded course, and if I choke, it could be disastrous. Will the Advance guys get angry if I go there and pretty much stumble my way through the course? Will the intermediate guys get angry if I come out and play well and win big? I think the Intermediate pool is going to be pretty small, it's a very tough course and I don't see a lot of Intermediate level players showing up.
Basically, what's the etiquette here for a new player playing in his first tourney?
Any other tourney advice, like on rules and decorum and stuff, would be welcome.


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Hello everyone. I feel like my bag isn't settled yet and I was hoping to get some expert advice on changes to my bag. A little background on me as a player.
I started disc golf about 5 years ago. Loved the game but went about starting the wrong way. I bought waaay to many heavy high speed discs not knowing that it takes a lot of time and experience to be able to throw those right. I did manage to pick up a teebird in that order which turns out to be my most reliable mold. I am a RHBH player that sprinkles in some overhand. Max distance on any given day is around 300-325ft. With all that being said here is my disc golf bag for criticism.
My Disc golf bag
167g –Destroyer-Star Plastic (This is my oldest (5 years) Driver. Fairly beat in, hard to flip and what I use for max distance with guarantee fade left. Wish I could buy 5 more of these)
170g –Destroyer-Star Plastic (Brand new and I hate it, cant throw it without it being a giant meat hook. Plastic feels firmer and less gummy than my other destroyer)
167g –Destroyer-Pro Plastic(Used to be my primary driver until it got beat in too much and flips too easily. Rarely throw anymore)
171g –Destroyer-Pro Plastic (Replacement for above disc, almost new and fades left too hard for my taste.)
172g –Firebird-Star Plastic (fairly new.Only used for forhand shots which I am not any good at. Heavy wind. Thinking about replacing it with a flick)
175g.-Boss-Star Plastic (both bosses are only used for Hyzer spikes and hard left turns)
175g –Boss-Star Plastic
Fairway Drivers:
167g -Teebird-Star Plastic (fairly beat in. Primary all around driver. What I throw 60-70% of the time.)
150g.-Teebird-Star Plastic (Same as above but for anhyzer shots)
170g –TL-Star Plastic (Throw it occasionally. Not really sure where it fits into my bag yet. Brand new)
178g.-Zombee-Z Plastic (Another disk I am trying out. Actually like it because it has no fade and will hold just about any line I give it. This is the disc I throw when I want to throw medium lasers)
165g –Leopard-Pro Plastic (Pretty beat, this is my full time anhyzer disc. Throw it straight and it curves right every time)
169g –Leopard Pro Plastic (Brand new. This is the disc I bought to backup my other leopard in case it gets lost. A much harder time bending it right.)
175g –Mako3-Camp Plastic (Love this disc. For when the putter isn't long enough and the driver is overkill. Ultra straight with slight fade)
Specialty Disk:
170g –Starfire-Champ Plastic (I only throw this disc for overhand shots. Probably about 2-3 times a round. Used to throw the firebird overhand but this one is by far better for me)
2x 170g –Challenger-FLX Plastic (Pretty straight for the most part. Cant complain much here)
I play DG in the north bay of California and most courses are fairly technical that I goto. Not a lot of opportunity to throw the big s curve shot.


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Fifth Judicial District Attorney race: Bruce Brown wants to work with Summit to right ship
October 17, 2012
Fifth Judicial District Attorney candidate Bruce Brown is running because he feels there has been a lack of leadership within the current office, and that change cannot come in the form of his competitor, Scott Turner.
"My opponent has been with the district attorney's office for five years. He considers himself a leader within that office," Brown said. "The change that needs to occur cannot come from within, it needs to come from outside the office and restore the confidence in the prosecutor's office to do justice by victims."
Among the issues Brown, a Democrat, takes with the current office: Only a very small percentage of Summit County's felony cases go to trial, he said, adding that "too many cases that go to trial are lost, and the cases that are resolved short of trial demonstrate a disconnect between the district attorney's handling of cases and our community conscious." Brown also says that 60 percent of the office's sexual assault cases are lost at trial.
"That's a disturbing situation for the community, as well as for those individuals," Brown said. "That has to do with trial skills."
If elected, Brown wants to give more mentoring to the young and inexperienced attorneys in order to give them more confidence in court, something he says will help with trial skills. Like his opponent, Brown is a fan of restorative justice, and would put it "foremost on the minds of every prosecutor in the court so that each defendant and each victim is being treated as an individual."
Brown also feels the current office turns a "blind eye" to high-priority offenders.
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"With respect to the offenders that truly constitute a public safety risk, this office is not doing a good job of identifying them and giving them a punishment that fits the crime," he said.
When it comes to those first-time or youth offenders, Brown has a different take.
"I think we can take a more holistic view with many cases toward young or first-time offenders to give them the opportunity to keep their records clean, and to improve themselves without becoming a fixture in the criminal courts," he said, adding that he supports juvenile diversion programs.
A Colorado Bureau of Investigation background check conducted by the Summit Daily found that at the age of 21, Brown was convicted of a misdemeanor larceny and fined $50 for stealing a plant.
"I think as a result of many life experiences I have strongly held opinions today, including the fact that when people do things and they're young and they make mistakes; it shouldn't be something that tails them for the rest of their lives," he said.
Brown also cites a lack of communication within the current district attorney's office, and says he will return the phone calls he alleges the current office doesn't.
"There's been a failure of leadership in the district attorney's office under Scott Turner," Brown said. "I know that by harnessing the skills I have, with the strengths of the Summit County community, we can work together to right the ship."
Brown is divorced and has three children. In his free time, he enjoys doing community service, coaching sports, skiing, hiking and vacationing.
Brown has been practicing law for 26 years. He grew up in California, and after graduating law school at the age of 23, began working for the Los Angeles public defender's office. After two years, Brown was handling his own cases and investigations. He went into private practice not long after, and has stuck with it ever since. Brown moved out to Colorado full-time in 2002, and currently works out of Idaho Springs. He served as the Clear Creek County coordinator for the Hickenlooper for Governor campaign.
Brown has never worked as a prosecutor – the closest work he does is in victim representation, he said – and alleges that his opponent's attacks on his defense background are misleading; Turner is trying to undermine his qualifications, he said.
"Frankly, I don't think I've ever seen a good prosecutor who is not a good defense attorney, or vise versa," he said. "Well over a dozen current and former prosecutors endorse my candidacy, as well as elected district attorneys. These are experts in the field who say this is a false test for the position."
Brown, like Turner, doesn't know his record, but said the assumption that it matters is false. Whatever it is, he's proud of it.
"I'm thought of in general as the lawyer who takes the tough and unwinnable cases. Sometimes I win, sometimes I don't," he said. "What I hope is reflected in my record is that I give 110 percent for every client, whether victim or accused. They leave the courtroom believing that I did everything possible for their case, win or lose."
Good lawyers are good communicators, he said, a skill Brown feels he can bring to the district attorney's office.
"From the standpoint of returning common sense to the courtroom, we need a change," Brown said.


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Turns out, it's a dicey proposition to build an NBA team around a group of players in their mid-30s, no matter how much talent those elderly gents may have. The current state of the Lakers bears that out.
Before the season, there were two potential impediments between the Lakers and the predicted dominance that followed their acquisitions of Steve Nash and Dwight Howard.
The first was chemistry, and that turned out to be an unsolvable problem. These Lakers could not get themselves organized into a workable system in the early part of the season and, just as bad, they didn't seem to like each other much. Thus the 9-14 start.
But the other potential problem — their age and susceptibility to injury — has cropped up throughout the year, and it is making its biggest impact now, at the worst possible time. The Lakers are trying to salvage some semblance of success this year by at least earning a playoff spot, but the effects of wear-and-tear have finally worn this team out.
It all came crashing down on Thursday in Milwaukee, the day that small forward (age 33) Metta World Peace underwent season-ending surgery on his left knee. Pile onto that pain in the back and hamstring for 39-year-old Steve Nash, the pain being attributed to a hip spasm and that forced him out of the loss to the Bucks in the third quarter.
Additionally, Kobe Bryant (he's 34) has a bone spur in his foot, and left the arena with the aid of a crutch. He will have an MRI on Friday.
After the game, coach Mike D'Antoni put it simply: "We're looking our age a little bit."
The timing could not be worse, of course.
The Lakers have just nine games left to play, and though seven of them are at the Staples Center, their opponents include the Grizzlies, Clippers, Warriors and Spurs. They play a pivotal game against the Mavericks on Tuesday — with Dallas making a charge and now just 1.5 games behind the Lakers for the No. 8 seed — and they close the year against Houston, which is currently holding the No. 7 seed.
It doesn't help, either, that the ninth-place team, the Jazz, is back to .500 after winning back-to-back games. The Jazz have 10 left to play, and six of those are at home where they've gone 26-9 this year.
The Lakers still have the inside track on the final spot in the playoffs, but the grip has become tenuous. Maybe this should have been predictable back in October, when the team came out with a starting five whose average age was slated to be 33.4 years by season's end.
Maybe it should have been even more predictable as D'Antoni essentially handed the team to Bryant, who has played 37.9 minutes per game and has played 40-plus minutes 22 times this year. Not only are the Lakers old, but their bench is thin, and hasn't offered much support for the starting geezers. The Lakers' bench ranks dead last in the league at 20.5 points per game, shooting 41.6 percent from the field and 33.9 percent from the three-point line.
The bad chemistry among the Lakers was on display early in the year.
Now, late in the year, the effects of age and a lack of depth are taking over.
The combination of the two not only kept the Lakers from being contenders, but it could keep them out of the postseason altogether.


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A Study to Determine the Clinical Significance of Molecular Detection of Breast Cancer in the Blood of Stage IV Breast Cancer Patients
This study has been completed.
Washington University School of Medicine
National Institutes of Health (NIH)
Information provided by (Responsible Party):
Washington University School of Medicine
ClinicalTrials.gov Identifier:
First received: July 19, 2006
Last updated: June 19, 2013
Last verified: June 2013
- Full Text View
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- No Study Results Posted
- Disclaimer
- How to Read a Study Record
This study is designed to determine whether molecular detection of breast cancer cells in the peripheral blood of Stage IV breast cancer patients is a clinically relevant predictor of progression-free and overall survival. Stage IV breast cancer patients who have measurable breast cancer metastases and are initiating a regimen of systemic therapy are eligible for enrollment. Multi-marker real-time RT-PCR analysis will be performed on peripheral blood specimens from 92 breast cancer patients and 120 healthy volunteers. Peripheral blood specimens from breast cancer patients will be obtained at the time of study entry (prior to initiation of systemic therapy) and at serial time points during follow-up. Subjects will be followed longitudinally until death, although the study has been powered so that the primary objective can be addressed after 12 months of follow-up. Healthy volunteers will be asked to provide a blood sample at time of enrollment but will not be followed.
|Breast Neoplasms
|Other: Blood draw
|Study Type:
|Study Design:
|Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary Purpose: Basic Science
|Official Title:
|Peripheral Blood Molecular Staging of Breast Cancer: A Prospective Cohort Study Designed to Determine the Clinical Significance of Molecular Detection of Breast Cancer in the Peripheral Blood of Stage IV Breast Cancer Patients
Resource links provided by NLM:
Genetics Home Reference related topics: breast cancer
MedlinePlus related topics: Breast CancerU.S. FDA Resources
Further study details as provided by Washington University School of Medicine:
Primary Outcome Measures:
- The prevalence of breast cancer cells in the peripheral blood [ Time Frame: 1 year ]Specifically, it is predicted that 60% of subjects with Stage IV breast cancer will have evidence of breast cancer cells in the peripheral blood by multi-marker real-time RT-PCR analysis, and that these subjects will experience a significantly decreased progression-free and overall survival.
Secondary Outcome Measures:
- Evaluate the prognostic significance of molecular detection of breast cancer cells in peripheral blood after initiation of systemic therapy. [ Time Frame: Until patient death ]Specifically, we will determine if molecular detection of circulating breast cancer cells after the initiation of systemic therapy is associated with a significantly decreased progression-free and overall survival.
- Quantify baseline molecular marker expression levels in the peripheral blood of healthy volunteers [ Time Frame: Approximately 12 weeks ]Determine if baseline molecular marker expression levels are dependent on patient age, race, and/or the presence of benign breast disease.
- Compare molecular analyses to the results of the CellSeach assay [ Time Frame: Approximately 12 weeks ]
|Study Start Date:
|November 2005
|Study Completion Date:
|February 2013
|Primary Completion Date:
|November 2012 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: Stage IV Breast Cancer
Blood draws at baseline before systemic therapy. Blood draw then every 6 weeks for approximately 12 weeks.
|Other: Blood draw
Healthy Volunteers
Baseline blood draw.
|Other: Blood draw
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
Inclusion Criteria - Stage IV breast cancer patients
- Patient age must be > 21 years.
- Patient must have a tissue diagnosis of invasive breast cancer.
- Patient must have documented evidence of metastatic disease.
- Patient must have measurable lesions.
- Patients must be initiating systemic therapy. Patients receiving hormonal therapy, and/or chemotherapy alone or in combination with other therapies are eligible.
- Patient must have an ECOG performance status of 0, 1, or 2.
- Patient must be available for follow-up.
- Patient or their authorized legally acceptable representative must consent to be in the study and must have signed and dated an approved consent form which conforms to federal and institutional guidelines.
- The patient with a previous history of non-breast malignancy is eligible for this study only if the patient meets the following criteria for a cancer survivor. A cancer survivor is eligible provided the following criteria are met: (1) patient has undergone potentially curative therapy for all prior malignancies, (2) patients have been considered disease free for at least 5 years (with the exception of basal cell or squamous cell carcinoma of the skin or carcinoma-in-situ of the cervix).
Inclusion Criteria - Healthy volunteers
A volunteer will be eligible for inclusion in this study only if ALL of the following criteria apply:
- Volunteer age must be > 21 years.
- Volunteer or their authorized legally acceptable representative must consent to be in the study and must have signed and dated an approved consent form which conforms to federal and institutional guidelines.
- Patients with benign breast disease are eligible for enrollment.
- The volunteer with a previous history of non-breast malignancy is eligible for this study only if the patient meets the following criteria for a cancer survivor. A cancer survivor is eligible provided both of the following criteria are met: (1) patient has undergone potentially curative therapy for all prior malignancies, (2) patient has been considered disease free for at least 5 years (with the exception of basal cell or squamous cell carcinoma of the skin or carcinoma-in-situ of the cervix).
Exclusion Criteria:
Exclusion Criteria - Stage IV breast cancer patients
A patient will be ineligible for inclusion in this study if ANY of the following criteria apply:
- No documented metastatic disease.
- No measurable lesions.
- Bone only and/or brain metastasis.
- Patient is not initiating a new regimen of systemic therapy.
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00355316
Please refer to this study by its ClinicalTrials.gov identifier: NCT00355316
|United States, Missouri
|Washington University School of Medicine
|St. Louis, Missouri, United States, 63110
|United States, South Carolina
|Medical University of South Carolina
|Charleston, South Carolina, United States, 29425
Sponsors and Collaborators
Washington University School of Medicine
National Institutes of Health (NIH)
|Principal Investigator:
|William E. Gillanders, M.D.
|Washington University School of Medicine
More Information
Additional Information:
Keywords provided by Washington University School of Medicine:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on September 21, 2017
Additional Information:
Alvin J. Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine
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Lockett MA, Baron PL, O'Brien PH, Elliott BM, Robison JG, Maitre N, Metcalf JS, Cole DJ. Detection of occult breast cancer micrometastases in axillary lymph nodes using a multimarker reverse transcriptase-polymerase chain reaction panel. J Am Coll Surg. 1998 Jul;187(1):9-16.
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Mitas M, Mikhitarian K, Walters C, Baron PL, Elliott BM, Brothers TE, Robison JG, Metcalf JS, Palesch YY, Zhang Z, Gillanders WE, Cole DJ. Quantitative real-time RT-PCR detection of breast cancer micrometastasis using a multigene marker panel. Int J Cancer. 2001 Jul 15;93(2):162-71.
Gillanders WE, Mikhitarian K, Hebert R, Mauldin PD, Palesch Y, Walters C, Urist MM, Mann GB, Doherty G, Herrmann VM, Hill AD, Eremin O, El-Sheemy M, Orr RK, Valle AA, Henderson MA, Dewitty RL, Sugg SL, Frykberg E, Yeh K, Bell RM, Metcalf JS, Elliott BM, Brothers T, Robison J, Mitas M, Cole DJ. Molecular detection of micrometastatic breast cancer in histopathology-negative axillary lymph nodes correlates with traditional predictors of prognosis: an interim analysis of a prospective multi-institutional cohort study. Ann Surg. 2004 Jun;239(6):828-37; discussion 837-40.
Mitas M, Hoover L, Silvestri G, Reed C, Green M, Turrisi AT, Sherman C, Mikhitarian K, Cole DJ, Block MI, Gillanders WE. Lunx is a superior molecular marker for detection of non-small cell lung cancer in peripheral blood [corrected]. J Mol Diagn. 2003 Nov;5(4):237-42. Erratum in: J Mol Diagn. 2004 Feb;6(1):58.
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|Responsible Party:
|Washington University School of Medicine
|ClinicalTrials.gov Identifier:
|NCT00355316 History of Changes
|Other Study ID Numbers:
05-0435 / 201109033
|Study First Received:
|July 19, 2006
|Last Updated:
|June 19, 2013
Keywords provided by Washington University School of Medicine:
Breast Cancer
Additional relevant MeSH terms:
Breast Neoplasms
Neoplasms by Site
Breast Diseases
Skin Diseases
ClinicalTrials.gov processed this record on September 21, 2017


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The Italy international has fallen down the pecking order at the Etihad Stadium recently but the backroom staff member backs him to force his way back into Robeto Mancini's plans
Manchester City defensive coach Angelo Gregucci believes that Mario Balotelli is ready to fight for his place in the first team after watching from the sidelines in recent weeks.
The former Inter striker has only started six matches for Roberto Mancini's side this season and was not included in the squad for the recent win over Tottenham.
With Sergio Aguero and Carlos Tevez forging a productive partnership up front and Edin Dzeko continuing to impress when called upon from the bench, speculation is rife that Balotelli's days at the Etihad may be numbered.
Mario Balotelli is 4/1 with PaddyPower to score two or more goals in Manchester City v Aston Villa
He told Sky Sport Italia: "Mario gave a great contribution [for Italy] and I saw in him the right attitude and behaviour.
"Mancini has chosen to give him a signal and it is his right to make choices. Perhaps during the last week something was missing but Mario is ready to take back the Manchester City shirt."
AC Milan have reportedly shown an interest in the mercurial striker and Gregucci remained coy on talk of a transfer away from Eastlands for the Italy international.
"Will he stay? It's not up to me to say," he added.
"I just know that he is definitely redeemable. He has 22 years of talent and quality.


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Shooter fans have been blasting their way through the Ark since midnight, and reviews of Brink are already pouring in. Here are a few to get started:
- MSNBC (9/10): "Brink is wickedly fun."
- The Sixth Axis (9/10): "Looking for an intense online shooter with more guns than Texas? Come on in, the water's fine."
- Eurogamer (8/10): "Brink is an exceptional team shooter, smart, supremely well balanced and with a unique, exciting art style."
- GamesRadar (8/10): "The mechanics of Brink's shooting, free running, and objective-oriented classes and skills are fantastic."
- The Guardian (4/5): "Brink deserves to be ranked among the finest co-op games available."
- CVG (8/10): "Hidden behind Brink's fancy new visuals and slick new style is a quintessentially old school team-based multiplayer title delivered with some noteworthy polish, real replayability and clever quirks."
- The Sixth Axis (9/10): "Looking for an intense online shooter with more guns than Texas? Come on in, the water's fine."
- FrontTowardsGamer (9/10): "Obviously, this game is a brilliant departure from the run of the mill shooters out there. "
- GameSpy (4/5): "Brink's greatest strength is that it presents these many tasks intuitively through an interface that constantly updates to provide players of each class with new jobs to do at the push of a button."
- IncGamers (8.8/10): "Brink is team-based in the truest sense."
- VGRevolution (9.4/10):But, if you are looking for a team based first person shooter where the game mode is about completing objectives then look no further."
- AusGamers (8.2/10): "… this is a different breed of first-person shooter: faster, sexier and made for online play."
- GamingNexus: "If you're looking for a solid team multiplayer game, Brink is a highly polished example with some enticing new ideas."
- ArsTechnica: "I tip my hat to the PC version: sir, you have delivered the goods."
- Crave Online: "A intuitive class-based shooter with style dripping out of every pore."
Elsewhere check out the Top 5 Reasons to be Excited for Brink at MLG and 15 Ways to Dominate at OXM UK.
Just for fun, here's the official launch press release copied below. See you on the Ark!
Bethesda Softworks Announces Brink Available Now
Highly Anticipated Shooter Now Available in Stores
May 10, 2011 (Rockville, MD) – Bethesda Softworks®, a ZeniMax® Media company, today announced that its acclaimed first-person shooter, BrinkTM, is now available in retail stores across North America, and will go on sale in Europe on May 13. Developed at Splash Damage, the game is available for the Xbox 360® video game entertainment system from Microsoft, PlayStation®3 computer entertainment system, and Games for Windows.
"We're excited to be getting Brink into the hands of gamers," said Pete Hines, VP of PR and Marketing at Bethesda Softworks. "It's clear from the response from fans who have had a chance to play the game over the last few months that fans are eager to play with and against their friends online."
Brink, an immersive first-person shooter that blends single-player, co-op, and multiplayer gameplay into one seamless experience, was named as the 'Game of Show' at Eurogamer Expo 2010, while Destructoid.com proclaimed "it's going to be one of the standout shooters of the year."
Brink allows you to develop your character playing alone, with your friends, and against others online. Featuring dynamic battlefields, extensive customization options, and an innovative control system, Brink lets you choose your side, Security or Resistance, as you engage in heated battle for control of the Ark. Once an experimental, self-sufficient and 100% "green" habitat, the Ark is now home to the original founders, their descendants, and thousands of refugees made homeless by the rapid rise of the Earth's oceans.
Decide the combat role you want to assume as you fight to save yourself and mankind's last refuge, one that is on the brink of all-out civil war.
Brink is rated T for Teen by the ESRB. For more information on Brink, visit www.brinkthegame.com.


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Using Puppy Pads to Housebreak your Puppy
Practicing the right techniques for house training your puppy will make the process easier for both you and the puppy. Many dog owners train their puppies to use puppy pads from an early age to reinforce the behavior of eliminating in a specific place, and later teach them to apply the behavior outdoors. A puppy pad is an absorbent pad with a leak proof backing that can be used indoors to teach a puppy to eliminate in a designated spot rather than on the floor. Here are some tips to keep in mind when using puppy pads to housebreak your puppy:
Praise your puppy when he uses the pad. Your puppy is eager to please you, and positive reinforcement is the best way to teach him your expectations. When he eliminates on the puppy pad, reinforce the behavior with praise and affection. Petting and talking to the puppy in an affirmative tone will give him positive associations with using the puppy pad, which will encourage him to use it in the future.
Give your puppy the opportunity to use the bathroom often. Young puppies need to eliminate frequently. Your puppy will likely need to go after eating, drinking water and after awaking in the morning or from a nap. Placing your puppy on his puppy pad at the right times can help him understand what you expect him to do there. If you catch your puppy in the act of eliminating elsewhere in your home, say "no" and place him on the pad (dogs live in the moment, so scolding your puppy when you did not catch him in the act will not get your message across).
Get in tune with your pup's potty routine. Does he sniff around before he goes? Does he go right after eating? If you can predict the times when he needs to eliminate, you can prevent accidents by taking him to his puppy pad to communicate what you want him to do. Keeping him on a regular feeding schedule and removing his water bowl at night will make his potty routine more predictable.
Be consistent. Particularly if your puppy is very young, he probably will not understand what you expect of him at first. Training your pup to use his puppy pad every time will take some patience, but sending a consistent message will help your puppy learn quickly.
Check back often for more puppy housebreaking articles and tips, or subscribe to our feed!
About MEDNET Direct: MEDNET Direct is a leading supplier of disposable medical supplies for the medical and veterinary industries, including top quality puppy wee pads designed as a training aid for puppy housebreaking. With over 10 million puppy training pads sold, MEDNET Direct makes medical grade pads affordable for veterinary and home use.
Labels: puppy house training, puppy housebreaking, puppy pad housebreaking, puppy pad how to, puppy potty training


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Pet Wash Fundraiser: Wash your dog at Pet Food Express from 9 a.m. to 7 p.m. May 4 and all the money goes to Operation Paws Rescue, which pays to spay/neuter unwanted dogs and then sends them to shelters for adoption. The cost is $15. Participating locations: Danville, Pleasant Hill, Concord, Lafayette. www.petfoodexpress.com.
Spring Fling Sale: The Animal Lover's Boutique, located year-round in the lobby of Feline Medical Center, will hold a special sale to benefit Jackie Barnett's Just Like New Fund, a Valley Humane Society program that aids sick and injured pets. In addition to animal-themed items, the sale will include garden art, home decor, hand-pained wine glasses, pillows, purses and gift baskets. 10 a.m.-4 p.m. May 4. 3160 Santa Rita Road, Pleasanton. www.valleyhumane.org.
Adopt A Rescued Rabbit: Contra Costa Rabbit Rescue and Contra Costa County Animal Services will have rescued rabbits available for adoption from 11 a.m. to 3 p.m. May 11 at Petco, 1170 Arnold Drive, Martinez. Free nail trims and grooming for rabbits is also available. See currently available rabbits at www.ccasd.org and www.contracostarabbitrescue.org.
Dog Walk-a-Thon: East Bay Animal Rescue and Refuge (EBARR) is holding it's annual Dog Walk-a-Thon from noon to 3:30 p.m. May 11, at Heather Farm Park, 301 N. San Carlos Drive, Walnut Creek. In addition to the one mile dog walk, there will be a doggy fashion show, dog wash, silent auction, raffles and vendors. $5 donation. 925-429-2785, http://ebarr.org.
Oakland Internet Cat Video Festival: This benefit for the East Bay SPCA features pet products, cats and kittens from animal rescue groups, kitten fostering information, arts and crafts, live bands playing cat-themed music, food trucks and a special appearance by "Dusty the Klepto Kitty." 3-10 p.m. May 11. Great Wall of Oakland, 2201 Broadway. $10 adults; $5 15 and younger. www.oaklandcatvidfest.com.
Beginning Birding: Interested in bird watching? Instructor Anne Hoff will introduce you to the tricks of the trade — binoculars, field guides, scopes and more; where to see birds and how to identify them. 7-8:30 p.m. Wednesdays, May 8-29 and 8-10:30 a.m. Saturdays, May 11-June 1. Golden Gate Audubon office, 2530 San Pablo Ave., Suite G, Berkeley. $105. $85 members. www.goldengateaudubon.org/news/beginning-birding-class-starts-on-may-8.
Noah's Ark Day: Meet birds, rabbits, dogs, cats and even honeybees during Noah's Ark Day at Christ the Lord Episcopal Church. Members of several organizations will be available to answer questions and discuss animal traits, behavior and care. Dogs, cats and birds will be available for adoption. 10 a.m.-2 p.m. May 11. 592A Tennent Ave., Pinole. email@example.com.
Rabbit Rescue: Meet two rescue bunnies from the House Rabbit Society in Richmond. For ages 3 and older. 11 a.m. May 18. El Cerrito Library, 6510 Stockton Ave., Free. 510-526-7512, http://ccclib.org.
"Little Eddy" Book Reading and Guinea Pig Adoption Day: Meet Pint and Half-Pint, Sinbad, Oliver and Jeannie, Caboose, Chili, Lavender and many more rescued guinea pigs needing homes. Talk with the experts about care and feeding, medical and housing needs and playtime. There will also be several readings during the day from the new book "Little Eddy and the Cabs of New York" and free bumper stickers. 2 p.m. May 18. Rabbitears Adoption Store, 6331 Fairmount Ave., El Cerrito. Free. 510-356-4233, www.rabbitears.org.
Maine Coon Cats: A cat adoption fair will take place from 11 a.m. to 3 p.m. May 18-19, at Wild Birds Unlimited, 692 Contra Costa Blvd., Pleasant Hill. See adoptable cats and kittens and fill out an application at www.mainecoonadoptions.com. (Adopters must be approved in advance). 510-710-9250.
Animal Feeding at Ardenwood: Check for eggs, bring hay to the livestock and learn the animals' favorite foods. 3 p.m. Thursdays-Sundays. Ardenwood Historic Farm, 34600 Ardenwood Blvd., Fremont. 510-544-2797, www.ebparks.org.
Loma Vista Farm: Field trips and tours are available for schools, day cares, garden clubs, senior centers and other groups, Monday through Friday throughout the spring and summer. 707-556-8765, www.lomavistafarm.org.
Fish Feeding Time: Get close to crabs and see flounder, perch and pipefish. 3-3:30 p.m. Saturdays and Sundays. Crab Cove, 1252 McKay Ave., Alameda. 510-544-3187, www.ebparksonline.org.
Adopt-a-Thon: Meet and adopt animals from Silicon Valley Animal Control Authority's rescue partners including: Mickaboo Companion Bird Rescue, Pug Rescue of Sacramento and SaveABunny. Admission is free and adopters can "pay what you want" in SVACA adoption fees. A dog training demonstration by DJ's Clever Canines will be held at 1 p.m. 11 a.m.-3 p.m. May 4. Silicon Valley Animal Control Authority Care Center, 3370 Thomas Road, Santa Clara. 408-764-0344, www.svaca.com.
Bird and Garden Tour: Pandemonium Aviaries will open it's doors to the public for a special behind the scenes tour of their rare bird conservation facility. The once a year event is a chance to see 40 exotic species of endangered birds, behind the scenes tours of state-of-the-art decorated aviaries and kid-friendly guided tours. 10 a.m.-6 p.m. May 11-12. Tickets must be purchased in advance. $75 for adults, $35 for kids, free for 3 and younger. Los Altos. www.supportbirds.org.
Fishing in the City: Learn to fish clinics teach the basics of fishing to children and adolescents ages 5-15. Equipment and tackle are provided. There is no charge for the clinics but there may be a park entrance fee. Each adult may bring two children; a driver's license is required for a rod loan. For information, email firstname.lastname@example.com.
Dog Book Reading Club: Do you love dogs? Want to learn more about their behavior, training, learning, body language, and using positive training methods? The Humane Society Silicon Valley Dog Book Reading Club meets from 2-4 p.m. fourth Sundays monthly to discuss a different book. 901 Ames Ave., Milpitas. Free. 408-262-2133, www.hssv.org.
Mobile Pet Adoption: Meet shelter animals seeking new homes and talk to Peninsula Humane Society volunteers about available pets from noon to 3 p.m. June 1 at Serramonte Center, Grand Court, Serramonte and Gellert Blvd., Daly City. www.peninsulahumanesociety.org.
Poochella Pet Fair: Information on microchipping, adoptions, spaying and neutering, pet portraits, nail trims, agility course and a guest appearance by the Petaluma Police Department Canine Unit. 9 a.m.-2 p.m. May 4. Fit 'N' Furry Pet Resort and Training Center, 860 Lindberg Lane, Petaluma. Free. 707-769-7387, www.fitnfurry.com.
Shark talk: David McGuire, Founder and Director of Sea Stewards presents his short film followed by a discussion about ongoing shark research and conservation. 7:30-9 p.m. May 9. Randall Museum Theater, 199 Museum Way, San Francisco. Free. 415-225-3830, www.sfns.org.
National Pet Week Celebration: This free event offers games for two-legged and four-legged friends, free microchipping, free pet toys, police canine demonstrations and pet adoptions. 11 a.m.-3 p.m. May 11. Little Marina Green, 3699 Yacht Road, San Francisco. 510-924-3309, www.marinatimes.com.
Spring Dog Festival: This fun event for dogs and their people includes games, food, demonstrations, shopping and more. 9 a.m.-2 p.m. May 19. Soquel High School, 401 Old San Jose Road, Soquel. $10 per dog, $5 per person. Proceeds benefit dogs in need. www.coastaldogs.com, 888-682-6972.
Gray Lodge Wildlife Area Guided Wetlands Tours: A wildlife naturalist will lead a group (minimum of 18 people) through the diverse wetlands of the Gray Lodge Wildlife Area. Learn wildlife identification and behavior patterns, conservations efforts and more. The experience can be customized to include requested information, along a half-mile walking route. For information and scheduling, call 530-846-7505 or email firstname.lastname@example.com. www.dfg.ca.gov/lands/wa/region2/graylodge/index.html.
Elkhorn Slough Ecological Reserve docent-led walks: 10 a.m.-1 p.m. Saturdays and Sundays. Binoculars and bird books available to borrow at no cost. Visitor Center and main overlook are fully accessible. Day use is $4.32 per person, ages 16 and older. Groups of 10 or more should schedule a separate tour. www.dfg.ca.gov/lands/er/region4/elkhorn.html.
Contra Costa County Animal Services
Send animal related events to firstname.lastname@example.com.