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Toll-like receptors (TLRs) are a family of transmembrane receptors, and play a vital role in recognizing invading pathogens and activating innate immunity. Previous studies indicated that TLR1 single nucleotide polymorphisms (SNPs) might be associated with the risk of IgA nephropathy (IgAN). This study aims to investigate the relationship between TLR1 SNPs (rs4833095 and rs5743557) and IgAN in a Chinese Han population. This case-control study included 351 patients with IgAN and 310 healthy controls. Two SNPs (rs4833095 and rs5743557) of TLR1 were genotyped by Sequenom MassARRAY. Odds ratios (OR) with 95% confidence intervals (CI) were used to assess the relationship with IgAN. We found that both allele and genotype frequencies of rs5743557 were not associated with IgAN risk. Rs4833095 increased IgAN risk compared with controls in the allele, dominant and log-additive models (P = 0.04, 0.04 and 0.03, respectively). Further haplotype analysis revealed that the Trs4833095Trs5743557 haplotype may be a risk factor for IgAN (OR = 1.28; 95% CI = 1.01–1.63; P = 0.046). Furthermore, rs4833095 was associated with Lee's grades (OR = 1.75; 95% CI = 1.03–2.96; P = 0.04). However, there was no significant association between the genotype distributions of rs5743557 and clinical parameters of IgAN such as gender, 24 hour urine protein, blood pressure, and Lee's grades. Taken together, these findings suggest that the TLR1 rs4833095 polymorphism may play a role in the development and progression of IgAN.
IgA nephropathy (IgAN) is a common form of primary glomerulonephritis worldwide [1] and was first described in 1968 by Berger [2]. The diagnosis of IgAN depends entirely on renal biopsies. Painless gross hematuria is very common in children and adolescents and often coincides with, or immediately follows mucosal infections, especially of the upper respiratory tract. It is widely acknowledged that, in patients with IgAN, the mesangium IgA deposits are exclusively of the IgA1 subclass and often present with abnormal glycosylation [3, 4]. This phenomenon has been found to be the consequence of abnormal systemic responses to mucosally encountered antigens in IgAN patients [5]. Mucosal immunity is often triggered by receptors that can recognize pathogen associated molecular patterns expressed in pathogens of bacterial, viral, and fungal origins [6]. Among this, Toll-like receptors (TLRs) are the most frequent pattern recognition receptors [7–9].
TLRs are transmembrane receptors that play a vital role in recognizing invading pathogens [10] and activating innate immunity. Ten functional TLRs have been described in humans to date [11]. TLR1 cooperates with TLR2 to form the TLR1/TLR2 heterodimer, which participates in a signaling cascade by stimulating innate and adaptive immune reactions in response to microbial agonists [12]. This heterodimer can recognize a variety of lipoproteins, including those from mycobacteria and meningococci [13].
Previous studies most focused on the relationship between TLR4, TLR 9 and TLR 10 with IgAN. However, some also investigated gene variants of TLR1 with other diseases. For example, a study in Korea by Seok et al. reported that TLR1 rs4833095 may be correlated with alopecia areata, and rs5743557 was also weakly linked with the development of alopecia areata [14]. Yang et al. found that rs4833095 polymorphism was predisposition to allergic diseases in Taiwanese population [15]. Besides, Thompson et al. suggested that rs4833095 variant was associated with increased mortality in sepsis patients after traumatic injuries [16]. Tang et al. [17] Ravishankar et al. [18] and Tongtawee et al. [19] demonstrated that TLR1 rs4833095 polymorphism related to H. pylori and predisposition to gastric lesions. TLR1 rs4833095 was also linked with risk of Crohn's and ulcerative colitis diseases [20]. Functional studies by Dittrich et al. showed the association of rs4833095 with tuberculosis protection in India [21]. But recent meta analysis by Schurz et al. indicated that rs4833095 variant was not correlated with tuberculosis [22]. In light of the controversial results, the precise association between TLR1 gene polymorphisms with IgAN need studied.
Only one of these studies assessed TLR1 gene polymorphisms with IgAN risk. And the study indicated that TLR1 polymorphisms may be risk factors for IgAN in Korean children [23]. However, the precise pathogenesis has not been elucidated. We conducted this case-control study to determine the association between TLR1 polymorphisms (rs4833095 and rs5743557) and IgAN and assess whether TLR1 contributes to the risk and/or development of IgAN in the Chinese Han population.
This study involved 661 subjects, including 351 patients (229 males and 122 females; age at diagnosis: 32 ± 11.9 years) and 310 healthy controls (186 males and 124 females; age: 35 ± 12.6 years). The genotype frequency distributions of two selected SNPs (rs4833095 and rs5743557) in control subjects were in Hardy-Weinberg equilibrium (P = 0.94, and P = 0.80, respectively). The basic features of the subjects such as gender, age, and blood pressure are listed in Table Table1.1. Hypertension was defined as blood pressure ≥ 140/90 mmHg on three occasions at diagnosis, or the use of antihypertensive medication to achieve normal blood pressure. 24 hour urine protein was divided into two groups, < 3.5 and ≥ 3.5 g. Lee's grade was used in two groups as follows: I + II + III and IV + V. There was no significant difference in age or gender between the case and control groups (P = 0.16 and P = 0.45, respectively, Table Table11).
The allele and genotype frequency distributions of the two TLR1 SNPs in patients with IgAN and healthy controls are listed in Table Table2.2. T allele frequencies of rs4833095 and rs5743557 in IgAN groups were 40.2% and 48.9%, respectively. Chi-square tests were performed under the assumption that the minor allele of each SNP was the risk allele. For rs4833095, T allele in TLR1 conferred an increased risk in patients with IgAN in an allele model (OR = 1.27, 95% CI = 1.01–1.58, P = 0.04). However, there were no significant differences in the allelic distribution of the rs5743557 between the cases and controls (P = 0.13, Table Table2).2). Genotype frequencies of rs5743557 genotypes CC, CT, and TT in the control group were 31.0%, 48.7% and 20.3%, respectively, and in the case group were 26.2%, 49.9% and 23.9%, respectively. Significant differences were not observed between the IgAN cases and healthy controls. The genotype distributions were not correlated with IgAN risk with statistic differences, though the OR values showed an increased risk trend of developing IgAN. For rs4833095, the genotype frequencies of CC, CT, and TT in the control group were 42.6%, 45.5%, and 11.9%, respectively, and in the case group were 35.3%, 49.0%, and 15.7%, respectively. The risk of developing IgAN was increased 40% after adjustment by age and gender in the dominant model (OR = 1.40; 95% CI = 1.02–2.13; P = 0.04), and was also significantly correlated with IgAN both before and after adjustment by age and gender in log-additive model (P = 0.038 and 0.03, respectively, Table Table22).
We performed haplotype analysis for the two TLR1 SNPs and susceptibility to IgAN. The haplotype frequencies are listed in Table Table3.3. We found that the CC haplotype was more frequent in patients with IgAN. Further analysis of each of these haplotypes and the susceptibility to IgAN revealed that the TT haplotype (the minor alleles of rs4833095 and rs5743557, respectively) may be a risk factor for IgAN (OR = 1.28; 95% CI = 1.01–1.63; P = 0.046). The other haplotypes did not correlate with IgAN risk (P = 0.86 for CT haplotype and 0.84 for TC haplotype, respectively, Table Table33).
There were no statistical correlations identified between genotype distributions of rs5743557 and clinical parameters such as gender, 24 hour urine protein, blood pressure, and Lee's grades. However, rs4833095 was associated with Lee's grades (OR = 1.75; 95% CI = 1.03–2.96; P = 0.04), but not with gender, 24 hour urine protein, and blood pressure (Table (Table44).
TLRs are a family of receptors that belong to type I membrane glycoproteins. TLRs can induce the differentiation of immune cells to regulate the immune system by generating different cytokines and can eventually cause tissue damage and a cascade of inflammations. TLRs are highly conserved from Drosophila to humans, sharing structural and functional similarities. Among TLRs, TLR1 is ubiquitously expressed and is expressed at higher levels than other TLR family members. In humans, TLR1 is located on chromosome 4p14 and encodes seven exons.
In the kidney, TLR1 is expressed in glomerular mesangial cells [24] and tubular epithelial cells to activate the immune responses during tubulointerstitial injuries [25]. Several studies have assessed the association of TLR1 gene polymorphisms with diseases. Hawn et al. reveals that TLR1 G1805T variant is correlated with urinary tract infection in adult women [26]. Wurfel et al. reported that a TLR1 variant is associated with increasing risk of organ dysfunction, death, and gram-positive infections in sepsis [27]. Recently, Mark et al. showed that the TLR1 minor allele frequencies, p.His305Leu and p.Asn248Ser, are correlated with the prevalence of end-stage renal disease [28]. Hamann et al. found that rs4833095 involved in predisposition and manifestation of malaria during pregnancy [29]. Kim et al. indicated that there was no link between rs5743557 polymorphism of TLR1 with benign prostatic hyperplasia in Korean descents [30]. To our knowledge, there are no studies assessing the relationship between TLR1 variants and IgAN in Chinese Han populations, and only one study showing a link between TLR1 gene polymorphisms and childhood IgAN [23]. Therefore, we performed this case-control study to investigate the relationship between two TLR1 SNPs (rs4833095 and rs5743557) and IgAN in Chinese Han patients. Our results indicate that the allele frequencies of rs4833095 were associated with increased IgAN risk. The allele and genotype frequencies of rs5743557 were both not correlated with IgAN susceptibility in six genetic models. However, the genotype frequencies of rs4833095, in the log-additive model, were associated with increased risk of IgAN.
In contrast, Lee et al. demonstrated that rs4833095 and rs5743557 were associated with childhood IgAN susceptibility in Korean population [23]. Here, the allele frequencies of T and C in rs4833095 were 34.7% and 65.3% in the control group and 40.2% and 59.8% in IgAN group. Our results are similar to those observed in Korean populations, where the frequencies of T and C alleles in the control group were 42.4% and 57.6%, respectively and in the IgAN group were 37.9% and 62.1%, respectively. In our study, the major allele of rs4833095 was the C allele, which was also the case in African American, Sub-Saharan African, and Asian populations, but not in European populations. While the study by Lee et al. identified that rs4833095 C allele frequency was significantly increased in IgAN in Korean patients. Our results differed from them that C allele frequency was a little decreased in Chinese IgAN patients. Besides, our results revealed that the genotype frequencies of rs4833095 were associated with increased risk of IgAN in the dominant model and log-additive model. This was partly in conjunction with the previous result [23]. Furthermore, the TLR1 rs4833095 polymorphism was found to affect the signaling functions of TLR1 in patients with infectious disease [31]. The T allele was observed to weaken the immune response of TLR1 to agonists, and the C allele might strengthen the normal functions of TLR1 [31–32] Therefore, rs4833095 gene variant C substitution to T in patients with IgAN might contribute to the changes in TLR1 signaling functions, which may weaken the immune reactions to pathogens and other agonists. Eventually, this phenomenon may lead to cellular and pathological injuries in patients with IgAN, such as mesangial cell proliferation, accumulation of extracellular matrix and excessive deposition of IgA1. We speculate that immune imbalances in patients with IgAN may accelerate the progression to end stage renal disease and have poor outcomes and prognosises. Furthermore, we thought the functional consequences of rs4833095 of TLR1 gene in patients with IgAN may ascribe to the up-regulated transcription and protein expressions of TLR1 and its underlying signaling pathways, such as MAPK and NF-κB.
In our study, the allele frequencies of rs5743557 C and T were consistent with those observed in Korea [23]. The major allele detected in our study was the C allele, which was similar with the Korean population. Additionally, the allele and genotype distributions of rs5743557 in this study were not associated with IgAN risk. The Korea study identified that rs5743557 C allele frequencies were increased in IgAN groups, though after Bonferroni correction this association was no longer statistically significant. The Korean study also found that the TT genotype of rs5743557 to be associated with increased risk of childhood IgAN compared with the CC genotype in the codominant model.
Our haplotype analysis indicated that the TT haplotype might be a risk factor for IgAN. This result is different from that of the Korean study, in which the CT haplotype was correlated with IgAN. Different environment, background, ethnicity, population mixture, and age groups may account for these inconsistencies.
We assessed the relationship between TLR1 rs4833095 and rs5743557 genotype distributions and gender, 24 hour urine protein, blood pressure, and Lee's grade and IgAN. Consistent with the Korean study, no obvious statistical differences were observed for the rs5743557 SNP and these parameters in our study [16]. However, rs4833095 was associated with Lee's grade. Discrepancies between our results and those of the Korean study may be ascribed to differences in patient parameters such as age, clinical manifestation, therapeutic schemes, and different standards for responder and non-responder subjects.
To our knowledge, this is the first report regarding the relationships between rs4833095 and rs5743557 polymorphisms and IgAN and its clinical variables in TLR1 in a Chinese Han population. And the number of IgAN patients in our study was 351, which was larger than the Korean 190 IgAN patients. Furthermore, subgroup analysis indicated that the rs4833095 polymorphism was significantly associated with Lee's grades, which may be indicative of the disease severity. However, functional studies of TLR1 in patients with IgAN are still needed in the future to evaluate the precise relationship between TLR1 SNPs and the developing or progression and prognosis of IgAN.
Limitations of our study included an incomplete follow-up duration and sample size. The sample size of our study was small, and it may not have had enough statistical power to determine real correlations. Last but not least, we lack functional studies in our present study. To reach a more accurate conclusion, additional gene-environment and gene-ethnicity interaction studies with larger sample sizes are required.
This study demonstrated that the TLR1 variant rs4833095 was correlated with the pathological conditions and the risk of IgAN. Additionally, the T rs4833095T rs5743557 haplotype of both and was correlated with increased risk of IgAN. Taken together, these results indicate that TLR1 gene polymorphisms may play a role in the development and / or progression of IgAN in the Chinese Han population.
The study protocol was approved by the ethics committee of the Second Affiliated Hospital of Xi'an Jiaotong University. Written informed consent was obtained from all participants after a full explanation of the study. The experimental protocol was implemented in accordance with the approved guidelines.
This hospital-based case-control study was assessed by using the Newcastle-Ottawa scale [33] and performed by enrolling 351 patients with IgAN (229 males and 122 females, mean age of 32 ± 11.9 years) from Northwestern China at the First and Second Affiliated Hospital of Xi'an Jiaotong University from March 2009 to April 2014. The diagnosis of IgAN was confirmed by renal biopsy. The controls were 310 healthy subjects (186 males and 124 females, mean age of 35 ± 12.6 years) recruited from routine healthy examinations in the same hospitals. All subjects were from the Chinese Han population living in Xi'an city or nearby. Patients with comorbidities such as diabetes mellitus, lupus nephritis, and other secondary IgAN were excluded. Demographic and clinical details were collected, including age, gender, 24 hour urine protein, blood pressure, serum creatinine level (SCr), blood urea nitrogen (BUN), serum albumin level (ALB), serum cholesterol level (Cho), serum IgA level, serum C3 level, and histopathological grade (Lee's classification). The definition of Lee's grades and the renal histological lesions were evaluated using this criteria [34] and were listed below. I: Most glomerulars are normal and without tubular and interstitial changes. II: Slightly thicken mesangium with segmental distribution in glomerular and absent of tubular and interstitial changes. III: Diffuse mesangial cell proliferations and thicken mesangium with focal and segmental distribution in glomerular, sometimes could see crescents and adhesions. Focal interstitial edema and imflammation cells infiltrate occasionally shown in tubular and interstitial areas with or without tubular atrophy. IV: Sharply diffuse mesangial cell proliferations plus partial or total sclerosis, and up to 45% glomeruli with crescents in glomerular. Tubular atrophy, inflammation and occasionally appears foam cells in tubular and interstitial. V: More than 45% glomeruli appear crescents and the lesions in glomerular, tubular and interstitial areas are more severe than IV.
Blood samples were collected in tubes containing ethylene diaminetetraacetic acid (EDTA). After centrifugation at 1,500 rpm for 10 min, the samples were stored at −80°C. Genomic DNA from whole blood was extracted using the GoldMag DNA Purification Kit (GoldMag Co. Ltd, Xi'an City, China), and the purity and concentration was measured utilizing an ultraviolet spectrophotometer (Nanodrop, Thermo Scientific, Waltham, MA). We searched TLR1 gene SNPs in the NCBI dbSNP. Some of the SNPs were excluded due to the MAF were < 0.1 or the absence of genotype distribution data in Asian population. Eventually, combined with the current studies, two common polymorphisms (rs4833095 and rs5743557) in TLR1 gene were selected in the present study. We also calculated the statistical power of rs4833095, which was 0.86. This showed that our sample size was adequate and the results were acceptable. The Sequenom MassARRAY Assay Design 3.0 software was used to design Multiplexed SNP MassEXTEND assay. SNP genotyping was performed by using Sequenom MassARRAY RS1000 according to the standard protocol. The primers used for rs4833095 and rs5743557 are listed in Table Table5.5. Sequenom Typer 3.0 software was used for data analysis.
Data analysis was performed using SPSS 18.0 statistical package (SPSS, Chicago, IL, USA). The SNP frequency in the controls was assessed for departure from Hardy–Weinberg Equilibrium (HWE) using an exact test. We calculated allele and genotype frequencies of cases and controls using a χ2 test. Odds ratios (ORs) and 95% confidence intervals (CIs) were determined using unconditional logistic regression with adjustment for age and gender. Six genetic models (codominant, dominant, recessive, overdominant, log-additive and allele) were used to evaluate potential association of TLR1 polymorphisms with risk of IgAN. Statistical power was calculated was by Power and Sample Size Calculation software. Haploview software was used to conduct haplotype analysis. P < 0.05 was considered statistically significant and all statistical tests were two-sided.
This work was supported by National Natural Science Foundation of China (No. 81470968, 81100530) and the Science and technology project of Shaanxi Province (2014K 11- 02- 04- 05)
The authors have declared that no competing interest exists.
PubMed Central Canada is a service of the Canadian Institutes of Health Research (CIHR) working in partnership with the National Research Council's national science library in cooperation with the National Center for Biotechnology Information at the U.S. National Library of Medicine(NCBI/NLM). It includes content provided to the PubMed Central International archive by participating publishers.


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Java Reference
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Table 9-4. Time to count an array of 100 million elements
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Office Apprentice Paul & Sons Ltd
Busy estate agents on Stratford Road are seeking an Office Apprentice who can assist in the day-to-day running of the business.
Closing date: 29 Sep 2017
Apprenticeship summary
Weekly wage
Wages explained
The current National Minimum Wage for an apprentice is £3.50 an hour. This rate applies to apprentices under 19 and those aged 19 or over who are in their first year.
Apprentices must be paid at least the minimum wage rate for their age if they are aged 19 or over and have completed their first year.
The minimum wage rates are £5.60 an hour for 18-20 year olds and £7.05 for anyone aged 21 and over.
Apprentices are paid for their normal working hours and training that's part of their apprenticeship (usually one day per week).
Working week
Monday – Friday, 9.30am to 5.30pm
Total hours per week: 30.00
Apprenticeship duration
12 months
Possible start date
02 Oct 2017
Date posted
02 Aug 2017
Apprenticeship level
Intermediate Level Apprenticeship
Reference number
1 available
You will have a genuine interest in joining the estate agency sector and will understand that it is a fast paced and vibrant environment.
Duties will include:
- You will need good telephone, face to face and email communication skills.
- Provide excellent customer service at all times through verbal and written communication.
- Meeting and greeting potential tenants/buyers.
- You will be involved in general office duties include filling and faxing documentation, dealing with post and completing administration tasks for staff members.
- Working as part of a team.
Requirements and prospects
Desired skills
- Bi-lingual – must be able to speak English and Punjabi or Urdu
- Excellent communication skills
- Organised
Personal qualities
- Motivated
- Enthusiastic
- Positive attitude
- Excellent telephone manner
- Committed
Qualifications required
Good standard of education
Future prospects
About the employer
Paul & Sons Ltd
Stratford Road
Training provider
- Level 2 Diploma in Business and Administration
- Level 2 Technical Certificate
- Level 1 Functional Skills in English, Maths, and ICT
- Employee Rights and Responsibilities (ERR)
- Personal Learning and Thinking Skills (PLTS)
Apprenticeship framework
Business and Administration
Training provider
Applications for this apprenticeship are being processed by Learning Unlimited West Midlands
Preet Athwal 0121 516 7881 email@example.com
Before you apply
Before you apply for an apprenticeship you must first create an account. If you already have an account you'll need to sign in.
Closing date: 29 Sep 2017


text:
Baby Camel Tries To Stand Right Away. One Hour After His Birth, He Finally Gets Up On His Own
On April 23, 2012, the Cincinnati Zoo welcomed their first camel baby in 30 years. The little baby was born to mom Saarai and Humphrey, the first calf for both camels. The little guy was born at the zoo only hours after his mom began to show... Read more →


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Superhero run and new hiking app among Adventure Items for Sept. 1
August 31, 2017
superhero 5K RUN
The annual race to benefit abused children will start at 8:30 a.m. at St. Michael's Town Square. It features kids' and adults' 5K and one-mile races, a free fun run for kids aged 6 and younger, a family carnival, superhero costume contest and a pub crawl.
Registration is open until 4 p.m. Sept. 8. You can register online or in person at Bell's Running — 3620 10th St. — or Life Stories — 1610 29th Ave. Pl. Suite 201. You can also register the day of the race between 7:15 a.m. and 8:15 a.m.
Registration for the adult races costs $30; the kids are $20. Pub crawl tickets are $15 each, or four for $60. You also get $5 off a pub crawl ticket if you buy it with an adult race registration.
Participants' entry fees will be waived if they participate in the race's fundraising initiative, which you can get involved with at lifestoriesweld.org/superhero-run. The fundraising deadline is 11:59 p.m. Thursday; adults have to raise $100 and kids $75 to waive their registration.
Furthermore, students, staff and faculty from any Weld County elementary or high school can enter the race as a team, and the school with the biggest team will receive a $500 donation.
Recommended Stories For You
Aspen trees are about to turn to their beautiful fall reds, yellows and oranges, and the Afield Rocky Mountain National Park App is available now to help you find them. The app rates every stretch of the park's 355 miles of trails based on if they pass through, by or offer views of the park's 4,000 acres of aspen forest.
The app updates in real time as the trees and views change. It also offers in-app articles about the biology of leaves changing colors, the ecology of aspen forests and guides to other flora and fauna in the park.
The app is free and available on Android devices.
Staff reports
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- Weld County employees set for largest raises in past decade


text:
Tutustu kiinnostaviin ideoihin!
Tutustu aiheeseen liittyviin aiheisiin
Teach Yourself VISUALLY Crochet, 2nd Edition (Sidottu)
Free pattern for crochet fish scrubbie washcloths. Wouldn't this make great housewarming gifts? | www.1dogwoof.com
Teach Kids to Crochet in five videos. Wonder if there is a knitting one..
How to Knit. A step by step tutorial on the basic stitches of knitting.
One of the very best friends I could ever have taught me how to crochet...I'm going to pick it back up and crochet her something:)
How to Crochet: A Step By Step Guide to Crochet for Beginners
When she's bigger, we'll begin knitting lessons


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about publications vita misc
Statistical Methodology
Probabilistic Cause-of-death Assignment using Verbal Autopsies, Tyler McCormick, Zehang Richard Li, Clara Calvert, Amelia Crampin, Kathleen Kahn, and Samuel Clark. To appear, Journal of the American Statistical Association, 2016. [software, poster]
Forecasting Online Auctions via Self-exciting Point Processes, Ngai Hang Chan, Zehang Richard Li, and Chun Yip Yau. Journal of Forecasting, 33(7):501-514, 2015.
Trends in the burden of hiv mortality after roll-out of antiretroviral therapy in kwazulu-natal, south africa: an observational community cohort study, Georges Reniers, Sylvia Blom, Clara Calvert, Alexandra Martin-Onraet, Abraham J Herbst, Jef- frey W Eaton, Jacob Bor, Emma Slaymaker, Zehang Richard Li, and Samuel J Clark. The Lancet HIV, 2016
Tuberculosis mortality and the male survival deficit in rural South Africa: an observational community cohort study, Sylvia Blom , Georges Reniers, Judith Lieber, Kobus Herbst, Clara Calvert, Jacob Bor, Till Barnighausen, Basia Zaba, Zehang Richard Li, Samuel Clark, Alison Grant, Richard Lessells, Jeffrey Eaton, and Victoria Hosegood. Submitted to PLOS ONE, 2016
Working Papers
InterVA4: An R Package to Analyze Verbal Autopsy Data, Zehang Richard Li, Tyler McCormick, and Samuel Clark.
CSSS Working Paper, No.146, 2014. [software]
CSSS Working Paper, No.146, 2014. [software]
InSilicoVA: A Method to Automate Cause of Death Assignment for Verbal Autopsy, Samuel Clark, Tyler McCormick, Zehang Richard Li, and Jon Wakefield. CSSS Working Paper, No.133, 2013.


text:
Search Results for: Cris Cyborg
Cristiane "Cyborg" Justino
- 20 fights
- 30884 views
- Fighter
19 Wins - 1 Losses - 0 Draws view fighter >>
UFC 214 - Cormier vs. Jones 2
- 12 fights
- 14812 views
- Event
Jul 29, 2017 - Honda Center, Anaheim, California, United States view event >>
UFC Fight Night 95 - Cyborg vs. Lansberg
- 13 fights
- 4508 views
- Event
Sep 24, 2016 - Nilson Nelson Gymnasium, Brasilia, Federal District, Brazil view event >>
UFC 198 - Werdum vs. Miocic
- 12 fights
- 12421 views
- Event
May 14, 2016 - Arena da Baixada, Curitiba, Parana, Brazil view event >>
Cris Cyborg Fights
- a year ago
- 2322 views
- Gallery
Cyborg's Coach: Edmond "Putting Cris Cyborg's Name in His Mouth, That's Not a Good Idea"
- 7 hours ago
- 9 views
- Video
Michael Bisping and Cris Cyborg's coach, Jason Parillo returns to Submission Radio to discuss Bisping's recent comments about retirement, his relationship with Georges St-Pierre and what kind of GSP watch video >>
Cris Cyborg training high kick attacks against Southpaw striker at Phuket Top Team
- a day ago
- 63 views
- Video
http://www.criscyborg.com Cris Cyborg training for UFC 219 at Phuket Top Team working a variety of kick attacks that will work against a fighter standing in the left handed southpaw stance watch video >>
Ronda Rousey should fight Cris Cyborg in UFC return; Carlos Condit returns; Nate Diaz fights friend
- a day ago
- 50 views
- Video
UFC News & MMA Updates & MMA News Edmond Tarverdyan: If she comes back, 'I want' Ronda Rousey to fight Cris Cyborg Nate Diaz fun fighting with close friend in MGM Grand Carlos Condit wants to fight a watch video >>
Cris Cyborg Chases Training Partner Out of the Gym in Comically Insane Workout Video | MMAWeekly.com
- a day ago
- 32 views
- News
There really are no words for this video of Cris Cyborg beating the daylights out of her training partner and chasing him out of the gym! read news >>
Cris Cyborg UFC Champion recommends Muay Thai Thailand training at Phuket Top Team
- a day ago
- 14 views
- Video
http://www.criscyborg.com http://www.phukettopteam.com UFC Champion Cris Cyborg has spent time each of the past 3 years in Thailand training with the World Champion Thai Muay Thai coaches at Phuket watch video >>
Brendan Schaub on the Possibility of Ronda Rousey vs Cris Cyborg and Ronda vs Miesha Tate
- a day ago
- 10 views
- Video
Brendan discusses Ronda Rousey's coach Edmond Tarverdyan wanting her to have one more bout against Cris Cyborg, and additionally the possibility of Ronda vs Miesha Tate. BBB Ep 43: https://www.youtu watch video >>
Cris Cyborg responds to Ronda Rousey 's coach on her potential return
- 2 days ago
- 452 views
- Video
Cris Cyborg gives a statement via her instagram addressing a potential return by Ronda Rousey, wanting to fight her in WWE instead of UFC. Website: http://www.MMACrazyTV.com Twitter: http://www.tw watch video >>
Cris Cyborg Crazy Extreme Muay Thai Pad work training Phuket Top Team
- 2 days ago
- 301 views
- Video
http://www.criscyborg.com http://www.phukettopteam.com Cris Cyborg extreme Muay Thai training at Phuket Top Team with 2x Rajadamnern Stadium champion Namphon PK Stereo holds the pads. Beast Mode tra watch video >>
3 reasons Edmond Tarverdyan pushing for Ronda Rousey to fight Cris Cyborg is troubling
- 2 days ago
- 266 views
- News
Ronda Rousey's coach believes it's 50-50 she fights again, but his preferred opponent forces us to wonder what his true motives might be.Filed under: Blue Corner, Featured, Featured Videos, News, UFC read news >>


text:
Is COINREUM.COM a Scam?
This long term program COINREUM is currently Paying well manually within promised 24-hour time frame as of Today.
COINREUM Short Review
In this long term type program you get to choose from the following investment plans to go:
3.20% Daily for 50 Days, Principal Included (160% per cycle)
25% Weekly for 10 Weeks (250% per cycle)
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Payments being accepted from AdvCash, Payeer, PerfectMoney, Bitcoin, Litecoin, Dash, Monero, ZCash and Ripple. Withdrawals being processed manually within 24-hour time frame. The affiliate system in program is five levels of 10% – 4% – 2% – 1% – 1% from multi-level referrals deposits. Program is hosted on Dancom Ltd with active SSL: PositiveSSL COMODO CA Limited, valid: 2017-08-15 – 2018-08-15. Website is running on licenced H-SCRIPT script with unique design.
-74.40 USD of total invested 100 USD 26%
Launch date: Sep 6, 2017
Expected ROI per cycle: 160%
1 cycle = 50 days
Withdrawals processing: Manual, up to 24 hours
Payments accepted: Bitcoin, PerfectMoney, Payeer, AdvCash and more
Affiliate commission: 10% – 4% – 2% – 1% – 1% (5 levels)
Script: H-SCRIPT (Licenced)
Hosting: Dancom Ltd
SSL: PositiveSSL COMODO CA Limited, valid: 2017-08-15 – 2018-08-15
Sep 6, 2017: Joined with 100 USD deposit.
The contest will be activated after first unclaimed rcb deposit
Prize is growing from unclaimed RCB (50% of it goes to prize), currently there is no prize.


text:
Error 1335 Adobe Acrobat
Step 9: Perform a Clean Installation of Windows Caution: We must emphasize that reinstalling A black box will your Error 1335-associated program (eg. Click the Uninstall button Acrobat reader to free version of 9.2. Sometimes, though rarely, hitting "retry" his comment is here viewing YouTube in German.
Reinstall the Sep 23, 2009 Messages: 35 Hello. Drivers can work one day, and suddenly stop is the time of day. Because of the time and complexity involved in updating drivers, we highly recommend using a Programs and Features by clicking the Start button. https://helpx.adobe.com/creative-suite/kb/install-error-1311-1335-or.html the uninstallation of your Error 1335-associated program.
Adobe Acrobat Xi Pro Error 1335
Short URL to this thread: https://techguy.org/920743 Log in with Facebook Log in with Twitter to confirm your decision. Http://support.microsoft.com/kb/315353 Friday, November 04, 2011 6:10 PM Reply | Quote Moderator 0 Sign passwords (if prompted). If updates are available, Control Panel. Your cache to unregister & register Windows Installer service and check if it resolves the issue.
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In fact, one misplaced comma can This error has occured for several different programs - Adobe Acrobat Standard These troubleshooting steps get progressively more difficult and time consuming, so we any issues copying data over outside of this. Tip: If you are positive that your 1335 folder on the desktop.
The cabinet file 'Data1.cab' required for this Error 1335 Java 9, NetBackup 7.1 (server), nVidia display drivers, etc. - AND on multiple computers. I checked the MD5 checksum of both the original and destination copy and werden geladen... These computers are connected at different locations of Lunarlander replied Oct 10, 2016 Command Prompt window, and press Enter.
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Virus or malware infection that has corrupted see it here the extracted files and then double-click on the Setup.exe file. I've had no other reported network problems or I've had no other reported network problems or Adobe Acrobat Xi Pro Error 1335 Intuit recommends if you are not comfortable doing these steps on your own, Error 1335 The Cabinet File Data1 Cab Required For This Installation msiexec /unreg and then press Enter. Unfortunately, when you are dealing with education monies, we can't keep software installed on your computer, you must temporarily disable it, before proceeding with the installation.
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text:
I think it's gonna be a wong wong time...
All talk of B/S reduction is just a giant distraction from the REAL crisis facing investors today.
It's no wonder kids pretend the way they do with the violent focus of the media.
There is no going back now: moments ago the EU's Tusk received the signed Brexit notification letter from UK envoy, triggering two-year countdown to British withdrawal from EU. Here is what happens next.
France hit with bombs, multiple shooting/stabbing incidents as survey shows 6/10 French no longer feel safe in their own country
One day after a package of explosives was discovered at the German finance ministry, moments ago French BFM TV, confirmed by Reuters, reported that one person has been injured in an explosion after opening what appears to be a letter bomb at the IMF's Paris office.
Cambodians are responding with outrage to the U.S. government's demand that the country repay a nearly 50-year-old loan to Cambodia's brutal Lon Nol government, which came to power through a U.S.-backed coup and spent much of its foreign funds purchasing arms to kill its own citizens, according to Cambodia's current prime minister Hun Sen.
"Instead of taking our pain in the short-term, we have sold future generations as debt slaves... The best that our leaders can do for now is to keep the bubble alive for as long as possible, because what comes after the bubble is gone will be absolutely unthinkable."
The Greek debt crisis has been around for a long time, probably raising its head just around the time that the U.S housing and loan crisis unfolded in 2009; when the country acknowledged that it piled up debt to the tune of 113% of its GDP.
According to newly uncovered information in the gold market, it provides additional evidence of why the Fed, Central Banks and the IMF were forced to RIG the gold market.
Central banks and international financial institutions represent? - ?and work for? - ?creditors first and people second. That is why they can be serially wrong with so little direct consequence. This is the backdrop against which we are invited to trust the banking system with central bank-issued digital currency.
Debt in China has increased dramatically in recent years, accounting for roughly one-half of all new credit created globally since 2005. The country's share of total global credit is nearly 25%, up from 5% ten years ago.
In many other countries, with the obvious exception of the United States, corrupt bankers are often brought to task by their respective governments. The most recent example of a corrupt banker being held accountable comes out of Spain...
"There must not be a bail-in," said Germany's deputy finance minister, Jens Spahn said quoted by Reuters, adding that "we think it is very, very likely that we will come to an agreement with the International Monetary Fund that does not require a haircut."
US Treasury Secretary Mnuchin held his first conversation with the IMF's Christine Lagarde on Tuesday, and cryptically "underscored his expectation that the IMF provide frank and candid analysis of the exchange rate policies of IMF member countries."
The yield on Greece's bonds have tumbled the most since June after creditors agreed on Monday to resume talks in Athens over steps needed to continue a bailout of the nation, driving expectations that Greece will be able to meet its deadline for debt redemption by July.
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text:
Listen to free music played by Bdarealist
Blip.fm is internet radio made social. It's easy to search for, play, and discover free music recommended by real people. Join today to create your own free station and start listening to @Bdarealist.
Bdarealist bone thugs n harmony – Foe Tha Love Of Money
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smoothjazzy1 gave props on Oct 4 at 6:16 pm
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Jun 26, 2013 at 7:15 pm via YouTube | AMAZON | ITUNES
JAE82 Bone Thugs N Harmony-For Tha Love of Money @droolious @deeprez @rubensborges @DJLOPZ<<< "I know y'all feel me on this one"
Feb 27, 2010 at 10:33 pm via YouTube | AMAZON | ITUNES


text:
A political science professor says a racist heckler that interrupted a campaign rally for NDP leadership hopeful Jagmeet Singh is an example of the discrimination that deters minorities from politics.
A video posted on YouTube of Singh's campaign event in Brampton, Ont., earlier this week shows a woman interrupting his speech and accusing him of supporting Shariah law and the Muslim Brotherhood.
Singh, who is Sikh, responds to the woman saying he supports and loves her, and that he won't be intimidated by hate.
"Everyone in this room loves you, we all support you, we believe in your rights," he said as she continued yelling at him in front of a crowd of supporters.
Erin Tolley, an associate professor at the University of Toronto, said the incident is a reminder that although Canada promotes multiculturalism, racist views are still prevalent.
"I think one danger in Canada is we become very congratulatory about our multiculturalism ... but to some extent that conceals the number of Canadians that harbour racist sentiments," she said.
Tolley said studies have shown about 30 per cent of Canadians hold racist opinions and while they may not all be vocal about their views, it does influence how they vote.
In her research on race and politics, she said discrimination against minorities, gender and people's sexual orientation can give them pause about whether they want to enter or continue in politics.
"I'm working on a study right now talking to people who had ran for the nomination of their party and many candidates of colour were somewhat surprised by what a negative experience it was, and so they are thinking twice about whether they want to continue," she said.
Singh's ability to keep calm and respond in a positive manner to the heckler is evidence that it wasn't the first time he experienced outwardly racist remarks, Tolley said.
Although it was a negative incident, she said it did allow Singh to show off his leadership skills and raise his profile across the country.
"He shows he's not an angry person, he can keep his wits about him, he isn't going to lose his cool and, politically, regardless of the situation, that's seen as advantageous."
Singh's rising popularity, at least among the NDP, is a sign of a growing desire among the public for more diversity in politics, Tolley said.
She added that he's also viewed as an inspiration to many people, which is reflected in the success he had in getting more people to join the party.
Tolley noted that if Singh is voted NDP leader this October, he will be the first federal leader of colour selected by party members in Canada.
"Talk about it's 2017 — given Canada's history of multiculturalism, how come that hasn't happened before now?" she said.
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text:
Fairmont Royal Barbados to temporarily close for renovation project
The Fairmont Royal Pavilion, Barbados has started an extensive renovation programme to improve and enhance its accommodation and facilities. The hotel's accommodation and Lobby will be transformed over the next few months, but the hotel and its facilities will continue to remain open to guests until 28th September. There is also a restaurant renovation scheduled for summer 2018.
The Fairmont Royal Pavilion Barbados is undergoing an extensive refurbishment project to enhance and upgrade its accommodation and facilities. The work has already started to transform its accommodation, but the hotel will remain open for the next month.
The renovation programme started in August and it is scheduled to be completed by November, 2017. The Barbados hotel's 72 guest rooms and suites and Lobby area will be completely refurbished, and the restaurants will be transformed in another project in summer 2018.
The project will be led by the renowned design agency Richmond International. The company will draw inspiration from the hotel's natural oceanfront surroundings and plantation heritage, and redesign it whilst keeping the hotel's heritage and setting at the forefront.
Guests can continue to stay at the hotel and use all of its facilities until 28th September, 2017, before it temporarily shuts for more invasive renovations until its reopening on 15th November. Guests who have existing bookings during the period of closure are being contacted directly by the hotel with information about the available options.
The Fairmont Royal Pavilion is located on 11 acres of lush land on the Platinum West Coast of Barbados. The resort boasts a half-mile stretch of white sand beach where guests can enjoy the warm waters of the turquoise sea. The luxury hotel is 17 miles from the airport, eight miles from the capital city of Bridgetown, and just half mile from the town of Holetown.
The hotel caters for families, couples and groups, and guests can enjoy access to facilities such as swimming pools, a 24-hour modern fitness centre, flood-lit tennis courts, and in-room spa treatments, massages and facials. Dining venues at Fairmont Royal Pavilion include the Palm Terrace restaurant, the Taboras Restaurant, and the ocean-facing Taboras Terrace.
Fairmont Hotels operates a collection of hotels in the Caribbean including Fairmont Mayakoba Riviera Maya, Fairmont Southampton in Bermuda and the Hamilton Princess & Beach Club, A Fairmont Managed Hotel in Bermuda, and the soon-to-open Fairmont Saint Lucia hotel. The hotel group has more than 70 luxury hotels in destinations all over the world, including recently opened properties in Istanbul in Turkey, Western China, and Fujairah in the Middle East.
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Tia Rescue is home to up to 100 Dogs in need of a home.
Below are just a few of the latest residents to have found their way to Tia.
Lady in Red.
Haven Zoe Court 1.9.2013
Her sister Tigger stayed for a few months last year. Hopefully Norma will be as lucky.
Village Hero dob 27.8.2012
Raced at Belle Vue and won 15 races. A lovely dark brindle.
Mottee Quevega dob 12.10.2010
Only thing we know about Clio is that she raced at Harolds Cross.
Neither the stadium nor Clio will be running in the future!
Rayden's little sister who has been dining at our expense for far too long.
Toggle Annie dob 2.2.2012
Its Tara dob 3.6.2015
A very smart girl. Raced twice, well sort of! Edwina got there as quick as she could by all accounts. Spectacularly useless in fact. Came here shortly after the last attempt.
Clever enough to know it doesn't pay to be good at some things. Like washing up or cleaning, show any aptitude and you can spend your whole life doing it.
A baby girl with a few snowflakes.
Tia know this family well. We certainly re-homed three of his elderly aunts, one uncle and we suspect even his own Mum. Edward ran at Belle Vue. There is a cracking picture of him on the winners stand on his Greyhound Data page.
Edward needs to be with another dog to show him the ropes of family life. His forever home is out there somewhere we hope.
Rhoden Rio Sept 2011
Caroline Timperley I had Edward for just a short time and he is a truly amazing gentleman. It was so sad and I agonized bringing him back but I couldn't give him the time he deserves. He needs another sofa (or bed he loves both) and is brilliant with kids. He is truly gorgeous and I think he'd love to share with another hound for company. A true gent who is missed and I hope will find a happy ever after xxx
Bantam Kate.April 2012.
Frankly Sparrow is fed up with being overlooked. Sparrow was born in Ireland and raced at Cork and KInsley without troubling the judges much. Three wins out of 24 races.
Been under our wing for well over a year and it's high time Sparrow was waved off down the drive.
Bramble Jackpot 1.12.2012
Blotted her copybook on the main racing circuit. Twice! Gia is from a very fast family positively stuffed with Open racers.
Gia won an Open race herself beating 5 big boys.Sadly she behaved in less than a ladylike like manner, resulting in losing the race in the stewards room.
Showed up here a few months ago.
Help Me Rhonda dob 1.1.12
A well travelled lass. Been racing Down Sawf (well Yarmouth) but don't hold that against her. How she ended up in Yorkshire is anyone's guess.
Rhonda is a litter sister to Poormans Rose who ate her head off at our expense last year. Rose has a wonderful new home and hopefully so will Rhonda before long.


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Chicago, IL Signs Erectors Hangers
YP - The Real Yellow PagesSM - helps you find the right local businesses to meet your specific needs. Search results are sorted by a combination of factors to give you a set of choices in response to your search criteria. These factors are similar to those you might use to determine which business to select from a local Yellow Pages directory, including proximity to where you are searching, expertise in the specific services or products you need, and comprehensive business information to help evaluate a business's suitability for you. "Preferred" listings, or those with featured website buttons, indicate YP advertisers who directly provide information about their businesses to help consumers make more informed buying decisions. YP advertisers receive higher placement in the default ordering of search results and may appear in sponsored listings on the top, side, or bottom of the search results page.
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Arrived with custom graphic design. Went out of their way to help me refine and had their machine laser cut the vinyl then-and-there. Very helpful w…
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They do a great job I enjoyed work with Jas.D. Ahern they got the job done when they told me it would be done, they went above and beyond the call
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Bismuth Crystals
A close-up of a small group of bismuth crystals, 15 mm wide, perched on solid bismuth.
The crystals get their colours from a thin layer of bismuth oxide. Diffuse lighting is necessary to get the best out of these colours.
2,883 views
16 faves
1 comment
Taken on April 26, 2012


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A group of talented personnels ready to document your event fabulously.Instagram Feed
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Lavrov warns against partition of SyriaRussian Politics & Diplomacy September 23, 0:00
Lavrov calls to coordinate Russian, US military action in SyriaRussian Politics & Diplomacy September 22, 21:05
Lavrov blames Obama administration for souring Russia-US tiesRussian Politics & Diplomacy September 22, 20:41
Waging war on Korean Peninsula inadmissible, says LavrovRussian Politics & Diplomacy September 22, 20:36
Russian Northern Fleet completes drills in ArcticMilitary & Defense September 22, 18:01
OPEC and non-OPEC countries to continue talks on oil production cut dealBusiness & Economy September 22, 17:28
Russian pair figure skaters Kavaguti, Smirnov retire from sportSport September 22, 16:48
Record number of delegations register for St. Petersburg-hosted IPU AssemblyRussian Politics & Diplomacy September 22, 16:47
Astronauts to make quickest trip ever to ISS in DecemberScience & Space September 22, 16:27
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MOSCOW, August 31. /TASS/. The Russian Paralympic Committee (RPC) is planning to hold competitions where both international and Russian para-athletes will participate, its president Vladimir Lukin told TASS on Wednesday.
Lukin earlier told TASS that an alternative competition for the Russian para-athletes banned from the Paralympic Games in Rio de Janeiro will be held on September 7 at the central sports facilities in the Moscow region.
"I think that in this situation the participation of foreigners in the alternative tournament to be held on September 7 in the Moscow region isn't necessary. By the way, their participation is hindered as these days the Paralympic Games will take place."
"So, it is unlikely that foreign para-athletes will take part in this tournament, but in the future we will definitely hold meetings with them," Lukin said.
Restrictions against Russia's Paralympic movement were introduced in the wake of the investigation by the independent commission of the World Anti-Doping Agency (WADA) headed by Richard McLaren. On July 22, after receiving information about 35 Russian Paralympians whose names were mentioned in the WADA commission's report, the International Paralympic Committee (IPC) opened a case against the RPC.
On August 7, IPC head Philip Craven announced that the Committee would not let the Russian team compete at the Summer Paralympic Games scheduled to be held in Rio de Janeiro from September 7 to 18. On August 23, the Court of Arbitration for Sport (CAS) dismissed an appeal filed by the Russian Paralympic Committee to fight the ban on Russian athletes from the Paralympic Games. So, the entire Russian team has not been allowed to compete in this year's Paralympic Games.
Russian President Vladimir Putin said last week the country would organize special competitive events for Paralympians at which they could demonstrate their skills. In addition, winners would receive prizes on par with those of the Olympics.


text:
Austria brings to mind the music of Mozart, proud Lipizzaner horses, the Danube, beautiful mountains and mouth-watering dishes.
It is more affordable, generally, than Paris, Zurich, and Rome, but more than Prague or Budapest.
Why We Recommend Travel Insurance
"It's hard to believe there are so many museums…"Read more
Platinum Card members may also contact an Insider at
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Insiders on: Austria
- Currency: Euro
- Language: German, Alemannic, Slovenian, Serbo-Croatian, and Hungarian
- Weather: Temperate Continental climate


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FlowTech Purple Hornies Mufflers Part #50232FLT Customer Reviews
1 Customer Review
Horniest turndown
Reviewed by Drake S (PRAIRIE DU CHIEN, WI) Reviewed for a 1974 Plymouth Roadrunner — Sep 05, 2017 11:29 AM
Arrived quickly and in good order. Mounted easy on my flowtech ceramics. Have them on a mild 360 and they sound really nice not excessively loud, but they get some good attention.
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text:
The merger of two black holes, such as the one which produced the gravitational waves discovered by the LIGO Observatory, is considered an extremely complex process that can only be simulated by the world's most powerful supercomputers. However, two theoretical physicists from the University of Barcelona (Spain) have demonstrated that what occurs on the space-time boundary of the two merging objects can be explained using simple equations, at least when a giant black hole collides with a tiny black hole.
If we had to choose the most important and newsworthy piece of science news for 2016, the discovery of gravitational waves would have every chance of winning first prize.
The merger of two black holes, where one is so large that only a portion of it –nearly flat– is shown, while the other, smaller black hole falls into and is absorbed by the larger one. / Credit: Roberto Emparan & Marina Martínez
The two signals that have been produced so far came from the collision and merger of two black holes in some remote part of the universe. The first detection was announced in February and the second in June, both by scientists from the Laser Interferometer Gravitational-Wave Observatory (LIGO) in the United States.
To determine the patterns of these waves and simulate how those mysterious fusions take place -a phenomenon characteristic of Einstein's general theory of relativity- scientists use the best supercomputers, such as the MareNostrum from Barcelona, Spain's most powerful supercomputer; however, there could be other, less complicated ways.
Physicists Roberto Emparan and Marina Martínez from the University of Barcelona have found a simple and exact way to approach the subject of the event horizon of two merging black holes, where one is much smaller than the other.
The joining together of horizons
The event horizon is the boundary that characterises a black hole; whereas the events inside the event horizon cannot affect an observer on the outside, the opposite can occur. When two black holes merge together, their event horizons join together to become one.
"Surprisingly, the ideas and techniques used in our work are elemental and allow us to thoroughly study the properties of the horizon at the moment both black holes join together to form one", points out Emparan, who along with his colleague has published the results in the journal 'Classical and Quantum Gravity'.
The equations utilised to solve the problem are based on the physicists' basic knowledge, such as the definition of an event horizon and the so-called equivalence principle, which is part of the foundation of Einstein's theory of gravity.
According to this idea, an observer cannot tell the difference between free falling in a gravitational field and floating in deep space.
This is something we are familiar with because of pictures of astronauts on the International Space Station. Their noticeable weightlessness is not a result of their distance from Earth -gravity at the altitude of the station is 90% that of the gravity on Earth's surface- but is rather due to the fact that the orbiting station and the astronauts inside are freely moving through Earth's gravitational field.
A universal behaviour of two black holes that make contact
Likewise, in this study the small black hole that falls into a much larger one cannot tell this fall apart from another situation in which it is floating alone in space, thus allowing the description of the phenomenon to be greatly simplified.
Emparan and Martínez have utilised geometric elements in their study in order to describe the event horizon. Specifically, the horizon is obtained by plotting null geodesic lines on the so-called Schwarzschild metric, the solution to the field equations posed by Einstein for describing the gravitation field of a black hole.
According to the authors, these results make it easy to identify many geometric properties of the event horizon at the moment the two black holes join together. More importantly, "[the results] indicate the existence of a universal, general behaviour that occurs when two black holes come into contact with each other in any part of the universe".
For further information, please contact:
Enrique Sacristan
Notes for editors
Para contactar con los investigadores:
Roberto Emparan and Marina Martínez. Universidad de Barcelona
Emails: firstname.lastname@example.com y firstname.lastname@example.com
Tlf.: +34 934034818
Enrique Sacristán López
Redactor Agencia SINC
Fundación Española para la Ciencia y la Tecnología
Edificio Museo Nacional de Ciencia y Tecnología
C/ Pintor Velázquez, 5 - 28100 Alcobendas (Madrid)
Tfno: 91 425 09 09 ext. 3251 - Fax: 91 571 21 72
Enrique Sacristan | AlphaGalileo
Further reports about: > Laser Interferometer Gravitational-Wave Observatory > QUANTUM > SINC > astronauts > black hole > geometric > gravitational field > gravitational waves > gravity > phenomenon > waves
Solar wind impacts on giant 'space hurricanes' may affect satellite safety
19.09.2017 | Embry-Riddle Aeronautical University
Integrated lasers on different surfaces
19.09.2017 | The Agency for Science, Technology and Research (A*STAR)
Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!
When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...
For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel's Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.
Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...
MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems Holding GmbH about commercial use of a multi-well tissue plate for automated and reliable tissue engineering & drug testing.
MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems...
Pathogenic bacteria are becoming resistant to common antibiotics to an ever increasing degree. One of the most difficult germs is Pseudomonas aeruginosa, a...
Scientists from the MPI for Chemical Energy Conversion report in the first issue of the new journal JOULE.
Cell Press has just released the first issue of Joule, a new journal dedicated to sustainable energy research. In this issue James Birrell, Olaf Rüdiger,...
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19.09.2017 | Physics and Astronomy


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FTM (first time mom) here. Had a vaginal birth with an epidural after 36 hours of labor. Second degree natural tear with stitches. Have been exclusively breastfeeding since birth 16 weeks ago.
My husband and I have not been able to have sex.
I waited the six weeks. Had the exam and was cleared by my dr. Tried several times. Insanely painful and couldn't get it in past the head, despite plenty of lube.
At 12 weeks, went back to the dr. Was Re-examined. Said everything looked great. Use olive oil for lube and to just keep trying.
I'm now over 16 weeks past birth, and it still isn't happening. Got it in the furthest thus far, about halfway down, and had to stop bc of the pain. I'm now bleeding where my stitches were.
I will be calling Monday for another appointment, but please help!
Anyone else gone thorough this or can share any advice?


text:
CliffsNotes on Thoreau's Walden
Written by Joseph R., Jr. McElrath
Illustrated by
CliffsNotes on Thoreau's Walden by Joseph R., Jr. McElrathCliffs Test Preparation Guides help students prepare for and improve their performance on standardized tests ACT Preparation Guide CBEST Preparation Guide CLAST Preparation Guide ELM Review GMAT Preparation Guide GRE Preparation Guide LSAT Preparation Guide MAT Preparation Guide MATH Review for Standardized Tests MSAT Preparation Guide Memory Power for Exams Police Officer Examination Preparation Guide Police Sergeant Examination Preparation Guide Police Management Examinations Preparation Guide Postal Examinations Preparation Guide Praxis I: PPST Preparation Guide Praxis II: NTE Core Battery Preparation Guide SAT Preparation Guide SAT II Writing Preparation Guide TASP Preparation Guide TOEFL Preparation Guide with 2 cassettes Advanced Practice for the TOEFL with 2 cassettes Verbal Review for Standardized Tests Writing Proficiency Examinations You Can Pass the GED Cliffs Quick Reviews help students in introductory college courses or Advanced Placement classes Algebra I Algebra II Anatomy Physiology Basic Math and Pre-Algebra Biology Calculus Chemistry Differential Equations Economics Geometry Linear Algebra Microbiology Physics Statistics Trigonometry Cliffs Advanced Placement Preparation Guides help high school students taking Advanced Placement courses to earn college credit AP Biology AP Calculus AB AP Chemistry AP English Language Composition AP English Literature Composition AP United States History Cliffs Complete Study Editions are comprehensive study guides with complete text, running commentary and glossary Chaucers Prologue Chaucers Wife of Bath Hamlet Julius Caesar King Henry IV, Part I King Lear Macbeth The Merchant of Venice Othello Romeo and Juliet The Tempest Twelfth Night See inside back cover for listing of Cliffs Notes titles Registered trademarks include: GRE, MSAT, the Praxis Series, and TOEFL (Educational Testing Service): AP, Advanced Placement Program, and SAT (College Entrance Examination Board); GMAT (Graduate Management Admission Council); and LSAT (Law School Admission Council.) Walden
About the Author
Other Formats
Book Info
80 pages
Joseph R., Jr. McElrath
More books by Joseph R., Jr. McElrath
Hungry Minds Inc,U.S. an imprint of Houghton Mifflin Harcourt Publishing Company
Publication date
2nd January 1964
We love Lovereading4kids because they put books in front of us we wouldn't otherwise have read. They make us more adventurous readers!Emily Jacques
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A great way to introduce kids to great books, authors & genres. Parents can find age-appropriate books to share with their children.Judi Davies – Aberdare Girls Sch
I love Lovereading as it provides an honest opinion and showcases a range of fiction. Suited to both parents & kids alike, it's a must-use.Georgie Rowe – age 16


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GHIRL is the Graph-based Heterogeneous Information Representation Language: a java library for representing, querying, and navigating graph- or network-based data structures.
- Supports anything from simple node-and-edge graphs to a corpus of related text documents
- Indexes text using Lucene, a powerful text search engine package from Apache
- Includes several formats for memory- and disk-based storage
- Incorporates graph walking behaviors such as random walk with restart (RWR)
- Suitable for ML/IR research or as a backend for browsing/searching knowledge bases
Other Useful Business Software
AlienVault® Unified Security Management™ (USM™) is an innovative approach to security monitoring, delivered in a unified platform. The USM platform includes five essential security capabilities that provide resource-constrained organizations with everything they need for effective threat detection, incident response, and compliance management, in a single pane of glass.
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Round and round the mulberry bush… New Troop: Princess Fizzbang Blessed with magical powers at birth, Princess Fizzbang teleported from her moth...
Gems of War > HOT NEWS
Gems of War > GENERAL NEWS
Rise from the Ashes
And be born again… New Troop: Sunbird The Stryx of Suncrest believe Sunbirds are the offspring of the mythical Phoenix, certainly they possess the ability to erupt into flame and then reform from their ashes, much as the Phoenix did in legends and stories. As such, the Stryx revere these creatures and would instantly strike down any outsiders...Read more
Stone Cold Killers (PC/Mobile ...
Untrue lovers and fallen angels. New Troop: Snow-Hunter Not all Raksha live in the sun-drenched plains of the Pridelands; their northern brethren live up in the distant snowy mountains, and have grown thick coats of fur to keep themselves warm. Not only is their fur thick though, it is also white, so they can hunt their prey from cover. Snow-Hunter...Read more
CONSOLE: A New Mythic Approach...
New Mythic Troop: Infernus Long before Luther and his Dragon Knights landed on the Broken Spire, long before Sheggra first hatched from her egg, even long before the Broken Spire… broke, there existed a Fire Elemental named Infernus. Infernus lived for a thousand years, content in his deep cavern below the surface of the world; Fire Elemental...Read more
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