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We explored the associations of aberrant DNA methylation patterns in 12 candidate genes with adult glioma subtype, patient survival, and gene expression of enhancer of zeste human homolog 2 (EZH2) and insulin-like growth factor-binding protein 2 (IGFBP2). We analyzed 154 primary glioma tumors (37 astrocytoma II and III, 52 primary glioblastoma multiforme (GBM), 11 secondary GBM, 54 oligodendroglioma/oligoastrocytoma II and III) and 13 nonmalignant brain tissues for aberrant methylation with quantitative methylation-specific PCR (qMS-PCR) and for EZH2 and IGFBP2 expression with quantitative reverse transcription PCR (qRT-PCR). Global methylation was assessed by measuring long interspersed nuclear element-1 (LINE1) methylation. Unsupervised clustering analyses yielded 3 methylation patterns (classes). Class 1 (MGMT, PTEN, RASSF1A, TMS1, ZNF342, EMP3, SOCS1, RFX1) was highly methylated in 82% (75/91) of lower-grade astrocytic and oligodendroglial tumors, 73% (8/11) of secondary GBMs, and 12% (6/52) of primary GBMs. The primary GBMs in this class were early onset (median age 37 years). Class 2 (HOXA9 and SLIT2) was highly methylated in 37% (19/52) of primary GBMs. None of the 10 genes for class 3 that were differentially methylated in classes 1 and 2 were hypermethylated in 92% (12/13) of nonmalignant brain tissues and 52% (27/52) of primary GBMs. Class 1 tumors had elevated EZH2 expression but not elevated IGFBP2; class 2 tumors had both high IGFBP2 and high EZH2 expressions. The gene-specific hypermethylation class correlated with higher levels of global LINE1 methylation and longer patient survival times. These findings indicate a generalized hypermethylation phenotype in glioma linked to improved survival and low IGFBP2. DNA methylation markers are useful in characterizing distinct glioma subtypes and may hold promise for clinical applications.
Human gliomas are histologically and molecularly heterogeneous CNS malignancies.1 These marked differences in histological as well as epidemiologic characteristics2,3 of glioma have prompted many studies that have revealed genetic4 and gene expression patterns that characterize different glioma subgroups. Less numerous are studies of epigenetic abnormalities, although such alterations, including aberrant DNA methylation of putative tumor-suppressor genes (TSGs), are powerful markers for classifying human cancer.5 We and others studying individual TSGs found hypermethylation to be more common among secondary glioblastoma multiformes (GBMs) than among primary GBMs.6–10 Other groups have reported coordinate methylation of multiple genes in glioma and have suggested that DNA methylation is associated with tumor grade.11–13 Given these observations, we hypothesized that different patterns of DNA methylation could delineate secondary from primary GBM and differentiate GBM (grade IV) from lower-grade gliomas. We examined a limited number of genes based on previous studies indicating significant alterations in DNA methylation status of the gene in human brain tumors: MGMT,14 PTEN,10 RASSF1A,15 RFX1,16 EMP3,6,17 TMS1,18 ZNF342,19 SOCS1,20 PEG3,21 MAGEA1,22 HOXA9,23 and SLIT2.24 Furthermore, we examined whether overexpression of specific oncogenes might be associated with aberrant DNA methylation to gain mechanistic insight into the epigenetic dysregulation of brain tumors.
The mechanisms responsible for hypermethylation of groups of genes in specific types of human cancers are obscure. Recently, attention has focused on the involvement of Polycomb repressive complexes (PRCs) in DNA methylation and particularly the enhancer of zeste human homolog 2 gene (EZH2),25 which is the catalytic component of the PRC2 and PRC3 complexes.26 EZH2 has been shown to control DNA methylation through its ability to produce the nucleosomal histone H3 lysine 27 trimethylation mark (H3K27me3) that provides a platform for recruiting DNA methyltransferases.27 PRC activation is linked to cell type–specific patterns of gene repression and DNA methylation through the H3K27me3 markings that are produced in stem cells.26 Thus, PRC gene targets in cancer progenitor cells may be preprogrammed for DNA hypermethylation that is triggered later during cell transformation.28–30 EZH2 overexpression is associated with aggressive clinical behavior in prostate, breast, and bladder cancers.31–37 The suppression of 14 genes that are direct PRC targets in embryonic stem cells defined a gene expression signature that was significantly associated with poor clinical outcome in multiple microarray data sets of tumors, including breast and prostate cancers.38 Although there have been no investigations of EZH2 in relationship to DNA methylation in glioma, EZH2 overexpression has been correlated with hypermethylation of APAF-1 in bladder cancer39 and PSP94 methylation in prostate cancer.40
An additional pathway we consider here is the PI3K/Akt pathway, because EZH2 has been shown to be a target of Akt phosphorylation, and the affinity of EZH2 toward histone H3 and related synthesis of H3K27me3 is greatly reduced in cells with activated Akt.41 Given the potential importance of H3K27me3 in controlling DNA methylation, we hypothesized that modification of EZH2 by Akt activation could affect DNA methylation profiles. We chose to use mRNA levels of the insulin-like growth factor-binding protein 2 gene (IGFBP2) as a biomarker of PI3K/Akt pathway activation on the basis of studies showing that elevated IGFBP2 is tightly linked to loss of the phosphatase and tensin homolog gene (PTEN) in GBM and that IGFBP2 may play a functional role in PTEN/Akt signaling.42,43 Supporting this latter notion are observations in murine models of glioma indicating that IGFBP2 plays a key role in the activation of the Akt pathway.44 Proteomic studies identified a strong correlation between high concentrations of PI3K, Akt-pThr308, and IGFBP2 among a 12-protein cluster that distinguished GBM from lower-grade gliomas.45 In primary human tumors, IGFBP2 mRNA levels are closely correlated with protein expression of IGFBP2 by Western blot analysis43 and immunohistochemistry.46 There is a well-established relationship between high IGFBP2 expression and increasing glioma tumor grade47–51 and the presence of necrosis, microvascular proliferation, and shorter survival times.46,48,49,51
We obtained 154 freshly frozen tumor tissues and 13 samples of nontumor brain from the University of California–San Francisco Brain Tumor Research Center tissue bank under appropriate institutional review board approval. The demographic and tumor characteristics for the glioma patients included in this study are presented in Table 1. Tumor samples were defined as secondary GBM if the patients had prior histological diagnosis of a low-grade glioma. All ages given are at the time of surgery, which occurred at the University of California–San Francisco between 1990 and 2003. Nontumor brain samples are portions of the temporal lobe that were surgically removed as a treatment for epilepsy and processed in the same way as the glioma specimens.
Genomic DNA and RNA were co-isolated from approximately 25 mg wet weight of each frozen tissue sample using AllPrep DNA/RNA Mini Kit (Qiagen) according to the manufacturer's instructions and eluted twice in a total of 100 µl of elution buffer. This procedure yielded 5–40 µg of genomic DNA. Bisulfite modification of genomic DNA was performed using the EZ DNA Methylation Kit (Zymo Research) according to manufacturer's protocol. CpGenome Universal Methylated DNA (Chemicon International) was chemically converted at the same time and used as a positive control/calibrator.
Candidate genes were selected based on previous studies showing their aberrant methylation in astrocytic glioma. See Supplementary Material, Table S1 for primer sequences and the size of amplicon. Because of heterogeneity in MGMT methylation, two different regions were targeted. Quantitative methylation-specific real-time PCR was performed on primary tumor samples using the Applied Biosystems 7900HT Fast Real-Time PCR System. The reaction plate was prepared with the Beckman Coulter automated liquid handler–Biomex 3000. Each reaction contained 10.0 µl of 2× Power SYBR Green PCR Master Mix (Applied Biosystems), 100–400 nM of forward and reverse primers, and 2 µl of DNA template in a total volume of 20 µl. For the amplification of EMP3, RASSF1A, and RFX1, 2–3% dimethyl sulfoxide (DMSO) was added. PCR conditions are modified by different primer concentrations, and the addition of DMSO ensured that primer dimers and nonspecific amplification product were not included in the calculation of threshold cycle (Ct). The dissociation curve and agarose gel were run to confirm amplification specificity. All genes were PCR amplified using SYBR Green Real Time PCR Master Mix (Applied Biosystems) under the following conditions: 95° C for 10 min followed by 40 PCR cycles of 95° C 15 s, 60° C for 30 s, and 72° C for 30 s. SYBR green fluorescence data were collected only during the 72° C extension step. Ct values were calculated by the 7900HT system software, and average relative quantification (RQ) values were obtained for each sample, where RQ = (target gene/ACTB) / (Universal methylation calibrator/ACTB).
We performed quantitative RT-PCR to determine the relative expression levels of EZH2 and IGFBP2 on primary tumor samples using a 7900HT Fast Real-Time PCR System (Applied Biosystems). Primers and probes were purchased from Applied Biosystems (ABI) as a premixed gene expression assay for each transcript (see Supplementary Material, Table S1). EZH2 has two transcriptional variants that encode two distinct proteins; we chose to utilize three assays, two of which would distinguish between each transcript variant and a third that would bind to a common region of both, in order to get a relative quantity for the total EZH2 expression. Samples were analyzed in triplicate for EZH2 variant 1, EZH2 variant 2, total EZH2, IGFBP2, and ACTB, which was used as the endogenous control. All targets were amplified under the following conditions: 95° C for 10 minutes, followed by 40 cycles of 96° C for 15 s, and 60° C for 1 min. All RT-PCR reactions contained a final concentration of 1× Taqman Universal Master Mix, no Amperase UNG (Applied Biosystems, p/n 4324018), 1× of each corresponding Gene Expression Assay reagent, and 3 µl of template cDNA. Relative quantitative expression was determined with Sequence Detection software v2.2.1 (Applied Biosystems) utilizing the delta delta Ct method as previously described.52 cDNA prepared from normal adult brain RNA (Clontech) was used as the calibrator sample.
Primers for real time-PCR were designed by using Primer Expression version 1.5 software (Applied Biosystems). The housekeeping glyceraldehyde 3-phosphate dehydrogenase gene (GAPDH) was used as an internal control for differences in DNA concentration. For each sample, the gene of interest and GAPDH were both amplified in triplicate, and results were analyzed by using Sequence Detector version 1.7 and Dissociation Curve version 1.0 software (Applied Biosystems). Relative quantification was performed with the standard curve method, and gene amplification levels were normalized by dividing by GAPDH levels in each sample. A cutoff of three copies was considered amplified. Haploid copy numbers were compared by the delta delta Ct method53 for the mean Ct of the reaction triplicates as follows: 2−ΔΔCT = ((1 + E)−ΔCTgene)/ ((1 + E)−ΔCTreference gene), where E = efficiency of the PCR reaction (set at default value 0.95), ΔCTgene = difference in Ct value between test sample and calibrator sample (BT71) for the gene under investigation (test gene), and ΔCT reference gene = difference in Ct value between test sample and calibrator sample (BT71) for the reference gene (GAPDH). (See Supplementary Material, Table S1 for primer sequence and amplicon size.)
Global methylation was estimated by measuring long interspersed nuclear element-1 (LINE1) methylation as previously described.54 Briefly, LINE1 region methylation extent was determined through quantitative bisulfite pyrosequencing. The method examines the cytosine methylation status at 4 cytosine-phosphate-guanine (CpG) sites in the LINE1 region. Each sequencing reaction was run according to instrument manufacturer (Qiagen) protocols on a PyroMarkMD System. Three PCR amplifications were performed on each sample and 2 pyrosequencing runs were done from each PCR, resulting in 6 replicates for each specimen to assess repeat measure variability. The average measure of LINE1 methylation across the 4 CpG sites was used for each individual tumor.
We used unsupervised learning methods to discover methylation patterns and explore associations with patient characteristics and tumor EZH2 and IGFPB2 expression. All analyses were conducted in the R statistical programming environment. We constructed visual representations of raw data using hierarchical clustering with average linkage, applied to pseudo-distances obtained as one minus the Spearman correlation among genes or among the geometric mean methylation for each histology. The resulting image plots were compared with model-based analyses described below. For unsupervised learning, we employed methods that assume discrete classifications (i.e., distinct methylation phenotypes). For discrete clustering, we used the Gaussian mixture model (GMM) framework.55–58 To address missing values among cases, we used a modified version of the GMM; here, the assumed multivariate Gaussian distribution for each methylation profile i, conditional on a given class, is N(μ*i, Σ*i), where N(μ,Σ) is the assumed distribution for the fully observed profile, conditional on the given class, and μ*i, Σ*i are the respective mean vector and covariance matrix obtained by deleting elements of μ and Σ that correspond to missing methylation observations for subject i. Cluster number was selected based on the Bayesian Information Criterion. We compared patient characteristics with methylation classes or propensities using chi-square tests for tabular data or analysis of variance, respectively. In the former case, we used permutation tests or exact methods to protect against possible small cell counts. We compared EZH2 and IGFBP2 expression among tumor classes using two-sample Student's t-tests. Survival follow-up data were available for 103 patients with methylation data. Associations of methylation classification with all-cause patient survival were examined using multivariate Cox proportional hazard models with adjustments for patient age, sex, and tumor grade.
The characteristics of the study population are presented in Table 1. To visualize the methylation data, we first performed unsupervised hierarchical clustering of samples. Interestingly, most lower-grade astrocytic or oligodendroglial tumors were grouped together with quantitatively higher methylation scores using qMS-PCR. Applying a mixture modeling approach, we next identified 3 classes of DNA methylation among the glioma and normal specimens (Fig. 1). The coordinate methylation of 8 genes (MGMT, PTEN, RASSF1A, TMS1, ZNF342, EMP3, SOCS1, and RFX1) defined a class of tumors that contained the highest methylation scores compared with the other classes. Among lower-grade tumors, 82% (75/91) fell into this most highly methylated class 1 (Table 2). Only 12% of primary GBMs were classified as class 1 compared with 73% of secondary GBMs. Nontumor brain specimens were almost exclusively assigned to methylation class 3 (92%), which contained the lowest methylation scores. The primary GBMs were relatively unmethylated with respect to the 8 class 1 genes but more often contained hypermethylation of HOXA9 and SLIT2. About 37% of primary GBMs fell into the class 2 methylation pattern that was driven by HOXA9 and SLIT2 methylation. Because MAGEA1 and PEG3 did not contribute significantly to the classification, they were not considered further.
The average ages at diagnosis for patients with the different subtypes of glioma were consistent with historical data.3 As expected, patients with secondary GBM were about 10 years younger than those with primary GBM. Of interest among primary GBM patients were 6 cases with class 1 hypermethylation, which is associated with early age of diagnosis and gliomas of lower grade. Patients with primary GBM with class 1 methylation patterns were younger at diagnosis compared with other patients with primary GBM (mean 47 vs. 55 years old and median 37 vs. 53 years old for class 1 GBM and class 2 GBM, respectively).
EZH2 (total) and IGFBP2 expression in relation to glioma subtypes and methylation patterns are summarized in Tables 3 and and4,4, respectively. EZH2 was overexpressed in all grades of glioma but was greatest among GBMs. The genomic region containing EZH2 was assessed for copy number changes in 60 tumors, including those containing the highest expression results. We found no evidence of EZH2 amplification, as all RQ values were <1.5 for all tumors tested (data not shown). No significant correlations were noted between amplification of the epidermal growth factor receptor gene (EGFR) or TP53 mutation and EZH2 (data not shown). Consistent with previous studies, IGFBP2 was highly expressed in GBM tumors (80%) and only rarely expressed in lower-grade astrocytic or oligodendroglial tumors (6%). Because IGFBP2 overexpression is so infrequent among lower-grade tumors, we focused our analysis on primary GBMs to explore the associations of IGFBP2 and EZH2 expression with methylation class. When the mean methylation score for the 8 genes that define class 1 methylation were regressed against the expression values for IGFBP2 and EZH2, EZH2 positively associated with class 1 methylation, whereas IGFBP2 was significantly inversely related to class 1 methylation among primary GBMs (Supplementary Material, Table S2). This result is graphically illustrated in Figure 2A and B. Those primary GBMs that fell into class 1 methylation clearly contain elevated EZH2, but in contrast to other GBMs demonstrated no or very low IGFBP2 expression (p < 0.008).
To explore possible relationships between gene-specific and global DNA methylation, we compared the LINE1 methylation scores among different subtypes of glioma and according to their DNA methylation class, as determined using our 12-gene panel. The results (Fig. 3) indicate significant differences in LINE1 methylation among glioma subtypes (p < 0.001). Relatively greater LINE1 methylation was common among astrocytoma, oligodendroglioma, and oligoastrocytoma. GBM tumors demonstrated the greatest heterogeneity in LINE1 methylation and the lowest LINE1 scores (global hypomethylation) among the subtypes. LINE1 methylation was significantly higher among those gliomas classified as having a class 1 (hypermethylation) pattern of genic methylation. Thus, coordinate methylation of genes having the class 1 pattern of methylation is accompanied by higher levels of LINE1 methylation.
The log rank test of Kaplan-Meier plots indicated a significant association of tumor methylation class with patient survival time (p < 0.001). The Cox multivariate analysis indicated that methylation class remained statistically significant when the model contained important predictors of patient outcome (Fig. 4). Class 1 pattern associated with hypermethylation of genes was associated with the longest survival times.
Ten tumors (4 oligoastrocytoma II and 6 oligodendroglioma II) had data on the 1p/19q deletion from Nimblegen array analysis of comparative genomic hybridization. All tumors, regardless of 1p/19q status, showed the class 1 hypermethylation pattern. Thus, 1p/19q deletion seems independent of DNA hypermethylation in this limited sample.
Although distinct DNA hypermethylation patterns have been recognized for some time in human cancer, only recently have mechanisms emerged that might explain the targeting of specific groups of genes for aberrant methylation. The clear differentiation of secondary from primary GBM by methylation profiles confirmed our a priori hypothesis based on studies of individual genes and indicates the potential clinical value of methylation profiles in distinguishing the two types of GBM. A recent study proposed using EMP3 methylation alone as a marker to differentiate secondary from primary GBM6 (Supplementary Material, Table S3). In addition to EMP3, the present study identified 7 other genes differentially methylated in secondary and primary GBMs. Combining our results with those of earlier reports7,8 could provide a highly discriminating panel for classifying these epigenetic subtypes of GBM (Supplementary Material, Table S3). In one case, both low- and high-grade glioma tissues were available, and we found that the class 1 pattern was retained in the high-grade lesion. Another potential application of such an approach is suggested by our results in primary GBM in which 12% of cases displayed a methylation profile highly similar to known secondary GBMs that progressed from lower-grade tumors. Younger aged primary GBM cases were overrepresented in this group, and we speculate that they may represent a distinct epigenetic subtype that arises from clinically unrecognized lower-grade lesions. Epidemiologic studies have suggested the existence of long-latency, high-grade glioma based on the significantly higher incidence of seizure disorders preceding GBM diagnosis by 8–11 years.59 Molecular features such as mutations of TP53 and amplification of EGFR suggest that younger aged primary GBM comprises different genetic subtypes,2 but the distinctions noted here based on methylation profile provide an even more robust segregation.
Our 12-gene panel contained two genes, HOXA9 and SLIT2, that are recognized as PRC targets in embryonic stem cells, whereas the others are not known targets. A significant result of our study is that glioma tumor types were segregated by DNA methylation profile according to the PRC target status of hypermethylated genes. The clustering of gene methylation in 37% of primary GBMs was driven by the hypermethylation of PRC targets HOXA9 and SLIT2, whereas the coordinate methylation of 8 non-PRC targets characterized secondary GBMs and astrocytoma stage II, anaplastic astrocytoma III, oligodendroglioma II, and oligoastroglioma II.
An additional aim of this study was to characterize patterns of aberrant DNA methylation in glioma and explore the potential roles of PRC and PI3K/Akt in these events by assessing the overexpression of EZH2 and IGFBP2 mRNA, respectively. We assessed EZH2 in primary glioma of different grades and found that EZH2 was overexpressed in most astrocytic and oligodendroglial tumors, but even more highly expressed in the higher-grade GBM tumors. Thus, our results follow the trend seen in other cancer types of increasing PRC pathway activation and aggressive tumor characteristics. We assessed three different qRT-PCR methods for EZH2 mRNA expression and found that both the short and long EZH2 isoforms showed very similar associations with methylation class (data not shown).The long EZH2 isoform was the predominant form in glioma, as has been reported previously in normal tissues.60 Previous studies postulated that gene amplification may be a mechanism for the induction of EZH2 in non-glial tumors.32 We found no evidence of increased EZH2 gene copy number in our study, which makes amplification an unlikely mechanism for EZH2 overexpression in glioma.
IGFBP2, like EZH2, was highly overexpressed in GBM but in contrast to EZH2 was not detectable among lower-grade astrocytic and oligodendroglial tumors (with the exception of two grade III astrocytomas). However, IGFBP2 levels varied considerably within primary GBMs, and lower IGFBP2 levels were observed among tumors with a distinct methylation profile and earlier age at onset. Primary GBMs without IGFBP2 overexpression exhibited a phenotype defined by methylation of 8 non-PRC targets. In contrast, PRC targets HOXA9 and SLIT2 were methylated in GBMs containing both IGFBP2 and EZH2 overexpression. Although our observation that IGFBP2 expression is associated with DNA methylation phenotype is novel, our study does not provide evidence that this relationship is causal with respect to PI3K/Akt. Nonetheless, any connection between IGFBP2 expression and PI3K/Akt pathway activation rests on the validity of IGFBP2 as a marker of this pathway. Several studies support this assumption42–45; however, there may be other phenomena such as tissue hypoxia61 that could be associated with both IGFBP2 expression and DNA methylation. Furthermore, our hypothesis that Akt activation could indirectly affect DNA methylation by phosphorylating EZH241 must be regarded as speculative, although the proposed pivotal role of H3K27me3 and EZH2 in controlling methylation provides a strong rationale for future studies to explore DNA methylation in cells with and without Akt activation. A recent study62 questioned the proposal that H3K27me3 is universally linked with DNA hypermethylation of PRC gene targets. The convergence of H3K27me3 with DNA methylation mechanisms was posited to be dependent on cell type.62 Our study provides a clue that PRC targeting for methylation may be modified by the activation status of the PI3K/Akt pathway. Supporting this idea further is our observation that a GBM progressing from an earlier astrocytoma II retained its class I methylation and low PRC target methylation and that both first tumor and second tumor were negative for IGFBP2 expression.
The finding that a pattern of gene hypermethylation correlated with LINE1 methylation indicates that a generalized mechanism operates in some subtypes of glioma, acting on specific genes associated with CpG sites as well as nongenic repetitive DNA regions. In addition, this evidence of epigenetic dysregulation was strongly linked with patient survival and low expression of the IGFBP2 gene. Taken together, these studies suggest a convergence of pathways that may offer new approaches for improving patient prognostication and therapeutic targets.
Our study has some notable strengths and limitations. One strength is our application of a quantitative MS-PCR method that has been shown to be superior to conventional MS-PCR for detecting hypermethylation patterns in human tumors. We also applied a novel unsupervised clustering methodology to create methylation classes that has advantages over conventional methods.58 A limitation of our work is the relatively small number of genes examined, which prevents us from knowing how generalizable our findings might be regarding PRC target and non–target gene methylation in different types of glioma. Future studies that expand the set of target genes interrogated will further inform PRC target versus nontarget methylation in these diseases. Our findings provide new insights into the associations of DNA hypermethylation profiles with 2 expression biomarkers that have strong connections to tumor progression and cancer survival.
Conflict of interest statement. None declared.
Grant support: ES06717, NCI CA126831; p50CA0927257.
Supplementary material is available at Neuro-Oncology journal online.
PubMed Central Canada is a service of the Canadian Institutes of Health Research (CIHR) working in partnership with the National Research Council's national science library in cooperation with the National Center for Biotechnology Information at the U.S. National Library of Medicine(NCBI/NLM). It includes content provided to the PubMed Central International archive by participating publishers.


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My email keeps getting bounced backAsked by tmuncie on March 17, 2017 at 10:43 AM
Hello, I sent an email last week about this, I have to keep checking my submissions every couple of days, because when my clients go to my website they fill in the contact us note and I never receive them. When I go to have it removed, it does not seem to fix it. Also...it says to use a good email. my firstname.lastname@example.com is the ONLY email I use for my business. Can you help me?
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If the emails are blocked or filtered, it will result in your address being placed on the bounce list. Unfortunately, we have no control over how Verizon does their filtering.
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If the above do not work for you, I would suggest using a different email address in the form. Use Gmail, if you have one, it tends to be quite lenient when it comes to filtering. You can then forward Gmail to your Verizon Email.

subset: commoncrawl


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May 24 (Bloomberg) -- Defaults on apartment-building mortgages held by U.S. banks climbed to a record 4.6 percent in the first quarter, almost twice the year-earlier level, as more borrowers failed to repay debt approved near the market peak, said Real Capital Analytics Inc. in a report.
Defaults on so-called multifamily mortgages rose from 4.4 percent in the fourth quarter and from 2.4 percent during the same period in 2009, the New York-based real estate research firm said today. Commercial-mortgage defaults also rose in the first quarter for loans against office, retail, hotel and industrial properties, Real Capital said.
"Apartment defaults are leading other commercial real estate," Sam Chandan, global chief economist at Real Capital, said in an interview. "Banks tended to make more aggressively underwritten apartment loans earlier during this last cycle. Credit and pricing reached their peaks for office properties and other commercial assets later."
The global recession cut demand for U.S. apartments, office space, retail shops, hotels and warehouses during the past two years as jobs disappeared and consumers cut spending. Defaults on apartment-building mortgages surpassed the previous record, set in 1993, for the past three consecutive quarters.
The U.S. savings-and-loan crisis drove apartment-building defaults to 3.4 percent in 1993. Defaults on other types of commercial property debt peaked at 4.6 percent in 1992, according to Real Capital.
The proportion of defaults on office, retail, hotel and industrial properties rose to 4.2 percent in the first quarter of this year, the company said.
U.S. apartments may lead a rebound in commercial real estate as vacancies peak in 2010 and the economy adds jobs, property research firm Reis Inc. said May 19. Reis estimates apartment vacancies will peak at 8.2 percent in 2010, the highest level since the firm began tracking the number in 1980. The number should start to decline in 2011, Reis said.
Real Capital bases its analysis on bank filings and data from the Federal Deposit Insurance Corp.
To contact the reporter on this story: Hui-yong Yu in Seattle at firstname.lastname@example.com


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Korean pop sensation Psy will appear on a May 21 episode of "Dancing With the Stars," continuing his inexorable march towards international super stardom.
He'll perform his hit single "Gentleman" on the equally popular dancing-themed reality show as the season winds to an end, and fellow musicians Pitbull and Wynonna will be putting in appearances as well.
Read more from GlobalPost: Psy hit sets Guiness World Record
Only four contestants remain on Dancing With the Stars: Kellie Pickler, Derek Hough, Ingo Rademacher of General Hospital fame and Kym Johnson.
You can watch Psy teaching Matt Lauer how to execute the "Gentleman" dance here. The track, which followed "Gangnam Style," set a Guiness World Record for the most-viewed video in a 24-hour time period. Impressive.
In the extremely unlikely event you haven't already heard this track five millon times (perhaps, for example, you live under a mossy rock), here's the video of "Gentleman."


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Switzerland's Water
By: Tanaya Battle
The problem at hand
Even though Switzerland do not suffer from water drought or contamination like many other countries, they do experience a large amount of rainfall which will occasionally result in flooding. "Switzerland's annual rainfall is so plentiful that if configured virtually the country would be one and a half metres under water." according to Max Maurer, chair of Urban Water Systems at the Swiss Federal Institute for Technology in Zurich.


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Roy Rogers,
Dale Evans,
Rex Lease &
Paul Harvey
William Witney
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DVD Features:
- Rated: Not Rated
- Run Time: 56 minutes
- Video: Black & White
- Released: January 26, 2010
- Originally Released: 1946
- Label: Alpha Video
- Encoding: Region 0 (Worldwide)
- Audio:
- Dolby Digital 2.0 Stereo
Performers, Cast and Crew:
|Roy Rogers, Dale Evans, Rex Lease & Paul Harvey
|Charles Williams, Sons of the Pioneers, Dale Evans & Rex Lease
|Directed by
|William Witney
Description by OLDIES.com:
Nevada Ranger Roy Rogers is recruited by the FBI to help investigate a counterfeiting ring that is passing a fortune in fraudulent dollars through the Vegas casinos. Arriving in town, Roy meets heiress Carol Randall, the newly elected Queen of the Helldorado Festival. Carol becomes Roy's unofficial Deputy, but when the investigation turns from simple counterfeiting to murder, she quickly finds herself in harm's way, making things even more difficult for Roy. Now the ranger must not only stop the murderous outlaws, but also keep Carol from being their next victim.
After performing in 44 westerns as Roy Rogers' comic sidekick, Gabby Hayes makes his final appearance with him in this 1946 production. Pat Brady, a member of Roy's back-up band, The Sons of the Pioneers, would take over the vacated second-banana role in subsequent films with the King of the Cowboys and in the hugely successful TV series that followed. Dale Evans, who had already appeared in several films with Rogers, became his devoted wife the following year.
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About Me
- Sandy
- Ohio, United States
- Happily married for lots of years to great guy, mother of one wonderful daughter. I have lots of interests and wished I had more time to explore them all.
Saturday, April 15, 2017
Donating Warm Mittens and More
This post was scheduled to post (or at least I thought it was), then I realized it was still in a pending status. Not sure whether it's a blog oophs, or an operator (me) oophs. Sorry for the delay in sharing this thoughtful donation with you all.
Thank you Dee Ann and please keep up the good work.
2016 Donations:
SCARVES (Gators, Infinity Scarves)295
**We started the year with the number of items we had donated last year, 2016; and will subtract our donations from that. Using the end number for 2016 as the goal for the each item. So, as the year continues you will see numbers decrease. Our goal is to meet and surpass the number of items donated last year.**
All donations regardless of size and number are valued. All donations are appreciated. The Power of One is awesome, and when we work together The Power of One becomes The Power of Many.
2 comments:
Wonderful hat and mittens Dee Ann! The colors are great for the homeless.ReplyDelete
- Yvonne in NDApril 18, 2017 at 4:51 PM
Mittens are so cool. I'm not much of a mitten maker so I appreciate people who are!ReplyDelete
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Where are You and Your Yarn From?
I'm trying to identify where everyone is from, partially for fun. Take a look at the map. Also, believe it will aid me in cases where we have several people with the same name. Please look at the lists of bloggers and non bloggers and see if I have the state you hail from. If not, please leave a comment and let me know.
Additionally, we've had help from Scotland, England, Germany Puerto Rico, Canada, and France! They don't appear on the map, but their help is still greatly appreciated.
Additionally, we've had help from Scotland, England, Germany Puerto Rico, Canada, and France! They don't appear on the map, but their help is still greatly appreciated.
Where The People Who Donate Come From, is your state represented?
visited 41 states (82%)
Create your own visited map of The United States or Amsterdam travel guide for Android


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What is JotForm?
JotForm is a free online form builder which helps you create online forms without writing a single line of code. No sign-up required.
At JotForm, we want to make sure that you're getting the online form builder help that you need. Our friendly customer support team is available 24/7.
We believe that if one user has a question, there could be more users who may have the same question. This is why many of our support forum threads are public and available to be searched and viewed. If you'd like help immediately, feel free to search for a similar question, or submit your question or concern.
Why are downloads limited to 200MB?Asked by vgg on August 14, 2016 at 07:21 PM
JotForm Support
I see you are referring to the "Download All Uploads" feature on the submissions page.
The 200MB limit is there to ensure that the user can download the files quickly. Trying to download all the uploads at once can take a long very long time, specially if the form has thousands of submissions, so the 200MB limit was set. If the user want's to download all the submission, they will need to download the files per set. So you can download the first set of 200MB files, then the next 200MB files, and so on.
You can check out this guide on how you can partially download each set of submissionsHow to Download the Submission Files. Regards.


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There are hundreds of reasons why I love Oregon, but this photo sums up a few of them nicely. The green, the moss covered rocks, the ferns ... Oregon is gorgeous.
"Like" Hood Photography on Facebook! Thanks!
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Sunday Snapshot


text: Reissue of the 1980 album by this obscure UK DIY / punk artist. I'd actually never heard of Afflicted Man (or its associated incarnations like Afflicted and Accursed) before this reissue came out, and that's seems crazy in retrospect because this is awesome! Sometimes UKDIY stuff can get a little too precious for my tastes, but this definitely has as much in common with 2nd-wave punk as it does with DIY staples like the Television Personalities and Desperate Bicycles. Basically, it sounds like semi-inept second wave punk, but with awesome melodic songwriting lurking somewhere beneath the din. They just don't make 'em like this anymore... recommended.


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Looking For Wilton Practice Sheets On Line.....
Decorating By thin4life Updated 24 Mar 2009 , 12:33am by all4cake
Does anyone know if these or anything similar is available on line? Any help would be much appreciated.
4 replies
I just googled wilton practice board(set is what ya want I think) and there were oodles of places that had them. Have you tried Wilton.com?
oh wait...you mean like to print off????


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Important and Diverse Types of Neurovascular Stents - Medical Research Reveals the Major Key Players and Other Developments in the Industry
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NBC Today - Transcript
MR. LAUER: Senator Barack Obama is in Charlotte, North Carolina this morning.
Senator, good to see you. Nice to have you with us.
SEN. OBAMA: Thank you, Matt. Great to talk to you.
MR. LAUER: Let's start where Andrea left off, this idea that when the guys challenged the gal at this debate this week, that in some ways you were ganging up on her. And you heard what Senator Clinton said at Wellesley yesterday. She said that in some ways that all-women's college prepared her for the all-boys' club of presidential politics.
Now, it sounds to me, Senator, as if I just heard the gender card drop. How are you going to deal with it?
SEN. OBAMA: (Laughs.) Well, look, I am assuming and I hope that Senator Clinton wants to be treated like everybody else. And I think that that's why she's running for president.
You know, when we had a debate back in Iowa a while back, we spent, I think, the first 15 minutes of the debate hitting me on various foreign policy issues. And I didn't come out and say, "Look, I'm being hit on because I look different from the rest of the folks on the stage." I assumed it was because there were real policy differences there. And I think that has to be the attitude that all of us take. We're not running for the president of the city council. We're running for the presidency of the United States of America.
MR. LAUER: So you don't feel as if you have to be sensitive at all to this gender issue, that if you do vigorously challenge Senator Clinton that it might take on a more perilous tone than if you vigorously challenge a male candidate?
SEN. OBAMA: No, look, I don't think that people doubt that Senator Clinton is tough. She's used to playing in national politics. And, in fact, that is one of the things that she has suggested is why she should be elected is because she's been playing in this rough-and- tumble stage. So it doesn't make sense for her, after having run that way for eight months, the first time that people start challenging her point of view, that suddenly she backs off and says, "Don't pick on me."
MR. LAUER: Let me --
SEN. OBAMA: I think that is not, obviously, how we would expect her to operate if she were president.
MR. LAUER: Let me turn to the subject of Iran. You gave an interview to The New York Times and you said that if you were elected president, you would, quote, "engage in aggressive personal diplomacy," end quote, with the leaders of that country. So we're talking about face-to-face talks and meetings with the likes of Mahmoud Ahmadinejad.
And you know you've taken some heat for this in the past. Senator Clinton called you naive. Some have said you would compromise the prestige of the presidency and this country by dealing with a terrorist leader or terrorist nation. Why are they wrong and why are you right?
SEN. OBAMA: Because since JFK said that we should not negotiate out of fear but we shouldn't fear to negotiate, I think that we have made progress consistently, whether it was negotiations with China or other countries, the Soviet Union, when we know where we stand and we are willing to go forward and say where we stand very clearly, to offer not only sticks but also to offer carrots, in order to try to accomplish some of our goals.
MR. LAUER: However, officials at the United Nations --
SEN. OBAMA: Now, I would be very clear with --
MR. LAUER: But officials at the United Nations, Senator, have met with the leaders of Iran, and yet Iran still defies some --
SEN. OBAMA: Matt, that's not the same thing for officials of the United Nations to meet. Now, we would be very clear with Iran and say, "We don't accept your development of nuclear weapons because that could trigger an arms race in the Middle East. We don't accept your funding of terrorist organizations like Hezbollah and Hamas. We reject totally your rhetoric with respect to Israel and will do whatever it takes to protect them."
But nevertheless, there is the potential, at least, for us finding ways of peacefully resolving some of our conflicts, and that effort has not been attempted. And if we don't make that attempt, then we are going to find ourselves continuing on the path that Bush and Cheney have set, and we're seeing the rhetoric rise every day.
It has consequences not only for our strategic interests. It has consequences for our troops in Iraq and it has consequences for our economy. There's a reason why oil prices are now approaching $100 a barrel, something that you talked about at the beginning of the show.
MR. LAUER: Exactly, and actually what I want to end this interview on, and that is the economy. You've seen all the economic data, Senator Obama. Are we headed into a recession?
SEN. OBAMA: Well, I don't know that we're headed into a recession. What I know is that we've got some structural problems in our economy. Part of it has to do with the war talk coming out of the Bush administration. Part of it has to do with the housing crisis and our failure to properly regulate some of the subprime lending that's been taking place. Part of it has to do with the fact that we still have an administration that has been operating irresponsibly when it comes to fiscal issues.
Those are the major structural issues that we are going to have to fix. The next president is going to have to be much more attentive to these problems and to restore some sense of balance so that we don't have a tax code that's giving huge tax breaks to folks who don't need it while ordinary families are struggling each and every day.
MR. LAUER: But in the last 10 seconds -- let me just go back to that, because as president of the United States, it would be your job to get ahead of the curve on something like a recession.
SEN. OBAMA: Absolutely.
MR. LAUER: So let me ask you again. In your gut, do you think we're headed to a recession?
SEN. OBAMA: In my gut, what I believe is that the economy has enormous strengths, but we have not attended to some basic issues that, if we leave unattended, then we're going to continue to have some problems.
MR. LAUER: But it's kind of a yes or no answer. You're not answering the question. Do you think we're headed to a recession?
SEN. OBAMA: But Matt, I'm not going to predict that we're going to go into a recession. That would be, I think, irresponsible. Right now what we need to do is figure out how can we get hold of our energy policy, how can we deal with this subprime lending crisis. If we do some key things short-term and then deal with issues like education long-term, there's no reason why the American economy can't continue to be strong.
MR. LAUER: Senator Barack Obama, joining us from Charlotte, North Carolina this morning. Senator, I thank you for your time.
SEN. OBAMA: Thank you, Matt.
Source: http://www.msnbc.msn.com/id/3032633/


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They Tell Him He's Going To Be a Grandpa – His Reaction Will Have You Laughing
July 29, 2015 | Videos
I think my reaction would be pretty similar to his! I love how he looks around to see if there's a camera, and boy was he wrong.
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by Jen Hubley Luckwaldt, PayScale
Note to readers: What did you do in college that contributed most to your career success? Share your advice with us on Twitter using the hashtag #College2Career!
If you're a college graduate, you've probably been asked at some point where you went to school and what you majored in. Judging by the pressure we put on high school students to choose the right school and the right major, college choice and concentration should be the most important factors in post-grad success. And while these choices are important—take a gander at the data to see what they say about how they affect alumni salary—the reality is that neither your school nor your major are absolute determinants of a successful career.
Yes, you should aspire to go to the best school you can get into (and afford), and you should definitely think about what you want to choose for a major. But, in the end, what you do while you're in school matters as much as, if not more than, where you go and which degree is listed on your diploma.
Create Your Own Destiny
"I went to a no-name school in Tennessee, so it was very unlikely that I'd end up at a large company like Microsoft," says Dallas Tester, a Developer Evangelist, who landed his first job there, straight out of college.
Working for Microsoft had been his goal since he was 16 years old. He found ways to get involved with the company via their Student Ambassador program, and participating in their Imagine Cup contest and winning third in the U.S.
"The best thing I did was take on extracurricular activities—TAing and being a Microsoft Student Ambassador," Tester says. His ambassador gig led to interviews and a job after graduation.
Your Guidance Counselor Was Right: You Need an Internship
If you're currently in college, or about to head there, you're probably already sick to death of hearing that you should be doing internships. If so, bad news: it's really true. Getting work experience while in school is one of the best ways students can prepare for life after college.
"I did NOT want to get an internship," says Sasha Pasulka, now Director, Audience Product Marketing at Tableau Software. "I was a B student. I wanted to spend the summer hanging out with my friends."
Pasulka's aunt, a recruiter, convinced her to attend a job fair on campus—by the simple expedient of not taking no for an answer.
"It was on a Saturday, and my sorority was having a pool party that day," Pasulka says. "I had no intention of missing the pool party. But my aunt showed up early to my tiny, messy apartment, instructed me to put on a nice outfit, took me to Kinko's to print out copies of my resume, and drove me to the recruiting fair. From that event, I wound up getting an amazing internship with Lockheed Martin, and they paid me—gasp!—$19/hr. It was more money than I'd ever dreamed I could make."
Pasulka returned to Arizona State University "with renewed drive" and earned a B.S. in Computer Science, and later went on to get an MBA at UCLA Anderson School. Other than one tricky physics class, she says she never got less than an A afterward.
...Even If It's Unpaid
Of course, not every internship is that well-paid ... or even paid at all.
"I can't stress enough how short-sighted college students are when they worry about landing paid internships," says Sarah Fenske, Editor in Chief of The Riverfront Times.
Fenske majored in English and Political Science at The College of Wooster, but landed a job right out of college at a mid-sized daily newspaper—no mean feat, considering that she wasn't a Journalism major and had no related coursework. Fenske's volunteer work with the campus newspaper led to an unpaid internship, which then led directly to her first job.
"Many unpaid internships will work with your schedule so you can take a paid job, too—in the summer of my unpaid internship, I was in the office only three days a week and spent my other days, and evenings, waiting tables," she says. "...Whenever possible, the key is to put the time in and, in the short term, care about learning a skill and making connections. If you're good at what you do, paid employment will follow."
How Important Is Choice of Major?
In fact, choice of major might not be as important as experience in the field. (Although it's never a bad idea to take some related classes, once you sense that your interest is headed in a certain direction.)
"Given that the average person changes jobs 10 – 15 times during his or her career, I think it's most important to choose a major that's interesting to you," says Alison Doyle, Job Search Expert for The Balance and CEO, CareerToolBelt.com. "One of the worst things you can do is pick a major that you think will provide you with lucrative employment, then end up hating the job you have. It's much better to spend time learning about what's important to you and then figure out where you want it to take you."
It's Never Too Early to Start Networking
College students would be well-served to think about networking sooner, rather than later. The connections they make in college can help them discover their dream career and then help them get hired in their new field. Part of the value of a "name-brand" school like an Ivy is the network that comes with being an alum. That doesn't mean that attending a school without a built-in network is a mistake, especially if it provides other opportunities at a price point that makes it easier to pay back loans—it just means students need to be prepared to build their own networks.
It's also a good idea to embrace the kindness of well-meaning relatives and family friends. Pasulka notes that her internship, which set her up for jobs at Honeywell and Northrop Grumman, wasn't just a good thing she did—"it was a wonderful thing my aunt did for me."
"I guess the lesson here is to build a support system of people who are more experienced than you and who have your best interest in mind—and then listen to them," she says. "Because, at a typical college age, you're probably kind of a moron."
Networking can also help you forge an atypical career path that's a perfect fit for you. Tom Cirrito, CEO and Founder, Filament BioSolutions, Inc., says that he's thankful for doing two things during his career as a Pre-Med student at Washington University, St. Louis: doing research from the very start ("not typical when you are pre-med, as it detracts from study time") and deciding to have a life while in college.
"I started as a lab rat at the age of 16, and understanding that lifestyle and the culture was the benefit," says Cirrito. "I did this but not just working in a lab, but volunteering to help out in the admin office, and becoming friendly (a.k.a building a network, and developing good relationships) with everyone in and associated with the lab, and even the clinical people."
His decision to stay social, while navigating a heavy course load might have changed the course of his career, ultimately shaping his decision to become an entrepreneur.
"I learned about people, which at the end of the day is what business is," he says. "...In fact, the experience contributed to my decision (perhaps the best decision of my professional career) NOT to go to medical school, and to get a PhD instead, which taught me a different set of analytical skills, and provided the optimal background for me to leverage my undergraduate research experience and ultimately become an entrepreneur in the life sciences."
The bottom line is that the college experience isn't just about choice of school or major, or even grades and academic achievements. Your college career is the first step toward the larger world of work that awaits you after graduation.
"The best thing students can do is to explore as many career alternatives as possible," says Doyle. "The more options you explore, the better equipped you will be to make decisions on meaningful employment after college—and the more employable you will be."


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A lecture on the 1912 flood that inundated Augusta will be presented on Wednesday at the Augusta Museum of History, 560 Reynolds Street.
"Water, Water Everywhere, the Anniversary of the 1912 Flood" will be given by Carol Waggoner-Angleton, an Augusta State University Reese Library archivist. The devastation caused by the flood and initial efforts to control flooding will be part of the talk.
The lecture begins at 12:30 p.m., and is part of the Brown Bag History Series, a monthly educational lecture series. Cost is free for members and $3 for non-members. Participants are encouraged to bring a lunch. The museum will provide beverages.


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Warning: By law we cannot sell this product to anyone under 18, by placing an order with us you are confirming that you are over the age of 18.
Orla Kiely
Orla Kiely Sicillian Lemon Diffuser Refill 200ml
This is a specialist veterinary product. We will ask you a simple set of questions to confirm that you are buying the correct medicine for your pet and know how to use it safely
Order by 3pm for Express Courier Delivery Some of the items we sell are a bit too bulky to fit on our delivery vans so we offer our customers Express Courier Delivery via courier. Deliveries are made from 8am - 8pm Monday to Saturday and 9am - 5pm on Sundays. Your delivery slot will only be confirmed once your order has been placed.
Blending the uplifting pure essential oils of Sicilian lemon, mint and lavender, with warm hints of frankincense for a truly vibrant fragrance.
How To Use
Carefully pour the refill liquid into the Orla Kiely diffuser. Allow 24-36 hours for the scent to diffuse into the room. For a stronger scent, turn reeds every two to three weeks.
Estimated Uses
Estimated Life Span
90 Days
Essential oils of Sicilian lemon, mint and lavender


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Virginia Beach, Virginia (PressExposure) June 29, 2009 -- As the summer rental season on the Outer Banks of North Carolina jumps into full swing, Currituck Countyâs Department of Travel and Tourism is celebrating the recent first-place platinum awards it received at the annual conference of the Destination Marketing Association of North Carolina. Beating large city destinations such as Raleigh, Charlotte, and Wilmington, Currituck County won the award for the Best Destination Marketing Initiative, owing this award to the successful implementation of a large-scale marketing campaign managed by the Virginia-based internet marketing agency Ciniva Systems.
In January, with Currituck experiencing the results of the nationwide recession and home owners expressing their discontent about reduced vacation rental spending, Currituck Tourism Director Diane Nordstrom approached the Currituck Board of Commissioners with a lofty request of $300,000 in additional funds for tourism marketing. Extra funds in hand, Nordstromâs team and Ciniva Systems collaborated to develop an internet marketing campaign aimed at attracting visitors to the website and ultimately securing vacation rentals in the county.
âWe used a variety of online marketing tools such as pay-per-click advertising [http://www.ciniva.com/ppc-marketing.cfm], email marketing, search engine optimization, and social media marketing to maximize campaign exposure and gain the best return on investment for Currituck,â states Ciniva President Steve Van Leeuwen. With over 20 million text, image, and interactive ad impressions, the campaign was able to bring in an average of 3,500 visitors per day during its peak, with about 70% of visits coming from first-time visitors. Boasting a conversion rate of over 50%, Currituck received more visitorâs guide requests than previous years, and the campaign is regarded as a huge success.
Homeowners and rental companies on Currituckâs Outer Banks have taken notice too. Ross Twiddy, marketing manager for Twiddy & Associates Realty, remarked in a recent Currituck press release, âWe saw a pretty good correlation between our bookings and their campaign.â This is a great boost of confidence for Currituck Countyâs Department of Travel and Tourism, which traditionally has some stiff competition from other regional vacation destinations.
Based on the success of the spring 2009 campaign, Nordstrom anticipates using existing funding for a supplemental fall campaign to keep the area in the tourism spotlight. âWhat Iâm hearing from the (tourism) industry is that our efforts are working; theyâre noticing a big increase in interest,â said Nordstrom in a recent Daily Advance article.
Currituck County Travel & Tourism Currituck is one of the fastest growing counties in North Carolina. Beautiful, clean beaches, a high quality of life, and the perfect blend of history have made this part of the Outer Banks a popular destination for visitors and locals alike. The tourism website can be reached at www.visitcurrituck.com.


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Buttoned shirt-jacket or shirt has collar and forward shoulder line. A, C with shaped side vents has patch pockets with buttoned flaps. B has elastic in lower casing. Long sleeves have buttoned cuffs. Pants with fake fly front have elastic in back waistline casing.
Links to reviews/blog posts Edit
Sources/Vendors Edit
Gallery Edit
[insert your photos of this pattern made up]
Wishlist Edit
[insert your username, and make sure your preferences allow for people to contact you via e-mail. Do not list your email address here!]


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Body wraps were invented by the Egyptians, who somehow knew mankind would one day need mummies to play the saxophone solos in Halloween party songs. Do the mash with today's Groupon: for $59, you get an express contour body wrap, plus your choice of a contour facial wrap or an aqua foot detox, at Wrapped in Wellness (a $150 total value).
Wrapped in Wellness encircles skins to create more contoured and captivating silhouettes. Those looking to cast a sleeker shadow can hunker down with the express contour body wrap, which uses heat and pressure to tighten and tone, reduce cellulite and stretch marks, and lose up to 30 inches, while flushing out toxins from their fat-cell foxholes and subcutaneous condos (a $105 value). Enhance the wrapsperience with a contour face wrap, infused with collagen and minerals to help lift and tighten saggy skin without the use of complicated hydraulics (a $45 value), or an aqua foot detox, which sends a mild current through a soothing seawater foot bath to eliminate ped-born toxins and restore a healthy pH balance (a $45 value).
During the treatments, which can last up to 2.5 hours, clients can watch a movie, listen to music, or twiddle someone else's thumbs to pass the body-trimming time. Besides winnowing away worrisome inches, the wraps can also rev up metabolic engines and improve skin's mildly indignant texture.
Wrapped in Wellness
Wrapped in Wellness's friendly staff helps bodies take on more toned and contoured forms through client-oriented services, organic products, and wraps that help clients lose up to 30 inches in one hour. They offer a variety of wraps including the LA Slim Wrap which is popular among some celebrities. Inside the tranquil wellness center, skilled technicians cocoon bodies in sundry wraps, which help bodies detoxify, tighten, and tone with all-natural mineral solutions that ready selves for red carpets, green screens, and awkward encounters with purple-clad paparazzi. In addition to body wraps and weight-loss treatments, the staff also darkens hides with airbrush tanning and enhances faces' youthful glow with rejuvenating facials. Calming décor envelops clients with soothing green and purple tones accented with touches of dark wood. Within private treatment rooms, rich curtains cascade to the floor as clients nestle into cushy furniture set aglow by warm lighting and left-behind glow sticks.


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I've sais many times that I don't make new year's resolutions, but I do set goals. However, they're generally career goals. This year, I began with a couple personal goals. Firstly, to get my finances in order andf start budgeting; and secondly to learn to play guitar (I've been threatening this one for years).
The good news is I'm on track for both. I bought myself the cheapest guitar I could find online and talked a work colleague into giving me some lessons (much to the chagrin of the Director of the Upper Hunter Conservatorium of Music, and organisation of which I sit on the board). I'm quite proud because after about six weeks, I appear to be making process. I can play something that sounds a bit like Bob Dylan's Knockin' On Heaven's Door and amd making a start on a basic 12-bar blues riff.
It's a strange mind of mid-life crisis I suppose but I'm enjoying it. I have the guitar (which I've named Jorge because he was cheap and I work him like a mule) siting behind my desk and I practice for at least fifteen minutes per day. Of course, as a prodigious researcher, I know far more about theory and guitar manufacture than about paying - so uch so that I'm off to Newcastle tomorrow to upgrade my guitar. Like all great guitarists through, I shan't be getting rid of my first. I'll let you know how it goes.
As for my finances, getting them in order has been somewhat easier. I stumled across a series of apps that have made my life a lot easier and make it quite simple to be accountable to my budget. Funnily enough, most of the resources I'm using are provided by the Federal Government! Who new the Government could be helpful?
So, 2017 is shaping up to be a pretty good year. Now, if only I could get my diet and exercise regime sorted!


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The FMT file extension refers to files that are usable by the FoxPro programming language. These FMT - FoxPro Format File extensions are used validate the data from within the the database program. These files are usually associated with a database format of some kind. Used in Visual Foxpro, FMT extensions can also be utilized by other programs such as dBase IV and Gate3 programming schemes.
File Extension FMT
Product(s) that can open FMT file
Oracle Database
Oracle Database When you are looking for a great and simple database to develop you will want to look at the Oracle Database. When you look at this you will...
Microsoft Visual FoxPro
Microsoft Visual FoxPro Microsoft Visual FoxPro is a tool that allows developers to build custom database solutions for personal or business use in a variety of different...
User Reviews


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West Coast Dog and Cat Rescue West Coast Dog and Cat Rescue
Here's a sample of our volunteer opportunities:VIEW AS
Mission Statement
Provides care and finds loving homes for companion animals in the Eugene/Springfield, Oregon community with a focus on those with special needs.
Our volunteers work with veterinarians, animal welfare groups and the public to help cats who are sick, injured, neglected or abandoned. We provide immediate medical care and place them in loving foster homes to heal and thrive. We evaluate them for adoptability and promote them for adoption via gracious partnerships with PetSmart, Petco and Wags! Dog Emporium in Eugene, Oregon.
Our 100% volunteer non-profit, no-kill program practices the philosophy to save all treatable and adoptable pets in our program. Since 2007 we have maintained our 501(c)3 status. Join us!
- Aven Wright-McIntosh
- (541) 225-4955
- Need admin access?


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Easy Lemon Souffles (Diabetic Friendly)
Be the first to review
READY IN: 50mins
Recipe by Crafty Lady 13
Light, fluffy lemon souffles that are low in calories, fat and carbs. Exchanges: 0.5 starch, 1 carb, 1 lean meat. Found this in the Spring 2013 Diabetic Living magazine. "The measure of achievement is doing something that you appreciate. I think of my souffle. I did that at least 28 times before I finally conquered it." --Julia Child
See Discussion:
Ingredients Nutrition
- 1⁄2 cup Splenda sugar substitute, sugar blend
- 1⁄3 cup all-purpose flour
- 1⁄8 teaspoon salt
- 2⁄3 cup nonfat milk
- 2 teaspoons finely shredded lemon peel
- 1⁄2 cup lemon juice
- 4 egg yolks
- 6 egg whites
- 1⁄4 teaspoon cream of tartar
Directions See How It's Made
- Preheat oven to 350°F Lightly coat six 8-ounce souffle dishes with nonstick cooking spray; place dishes on a baking sheet. Chill dishes.
- In a small saucepan stir together sugar, flour and 1/8 tsp salt. Whisk in milk and lemon juice. Cook and stir over medium-low heat 8 to 10 minutes or until thickened and bubbly. Stir in peel. Remove from heat.
- In a large bowl beat egg yolks with an electric mixer on medium to high speed 3 to 5 minutes or until thick and lemon color. Stir milk mixture into yolks to combine.
- Thoroughly wash beaters. In another large bowl beat egg whites with an electric mixer on medium to high speed until foamy. Add cream of tartar. Beat on high speed until stiff peaks form (tips stand straight).
- Gently fold egg whites into milk mixture. Divide batter among prepared dishes. Bake 20 minutes or until a knife inserted near centers comes out clean. If desired, sift powdered sugar over souffles. Serve immediately.


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Melissa Humphreys
Sarna News
|Melissa Humphreys
|House Humphreys
| Profession/
|Duchess of Andurien
|Richard Humphreys (father}
Melissa Humphreys (Born 2528 to 2624)[1] - House Marik Noblewoman, Star League diplomat, and Political Leader of the Andurien Provience.
Character History[edit]
Early Life & Career[edit]
Only daughter of Duke Richard Humphreys, she was raised to be his heir and given an extension education which included; Economics, Military Schooling, and Politics. She briefly had a succeesful military career and went into politics where she arose from regional assembly to the Free World League's Ministry of Foreign Affairs.[2]
Highlights of her Political Career[edit]
As Minister, she played pivotal role in negotiations that lead to the formation of the Star League. She proved her mettle during the negotiations by standingup to the leadership of Hegemony and her own nation. She would witness signing of the Star League Accords and received one of the pens used to sign the document in 2571. She remained as important diplomat through the Star League first decade, where at times she served as proxy for Captain-General.
During the Reunification War, she would instructed to prepare plans for the reconstruction of the Magistracy of Canopus.[3] After Magistracy's surrender to Star League forces in 2588, she was dispatched to take over as their Military Governor.
As governor she put into action of her plans rebuild the nation which includes; Rebuilding nation's infrastructure, creating a Central Committee to keep control the Magestrix and universal suffrage for men.[4][5] Her governence of the Magistracy was first marred with unrest, however as time went by her beign rule subsided this unrest. As time went by while working with Magestrix Crystalla Centrella.
Her reconstruction efforts which would later be called the "Good Neighbors" policy, bring in funding that outmatch the Star League aid to rebuild. By 2604, she would turn over control of the Magistracy back to its government and retire from Star League service and become special ambassador to Captain-General.In 2614 she would return from retirement become aide to dying Captain-General Rhean Marik for remainder of her rein.[6]
Melissa's efforts and belief in ideals of the Star League led to prosperity of the Magistracy of Canopus which she credit for.[7]
Positions and Titles[edit]
Title and Position[edit]
|Preceded by
Richard Humphreys
|Duchess of Andurien
| Succeeded by
|Preceded by
|Military Governor of Canopus
| Succeeded by
Game Rules[edit]
Under AToW RPG System, Melissa Humphery's is has +1 modifier for any Negotiation Checks if she in party (+2 if takes direct hand in the negotiations.) and +1 for any Administration Action Checks.[8]
- ↑ Historical: Reunification War, p. 54-55 Melissa Humphreys/Profile - Day of birth & Death of the character.
- ↑ Historical: Reunification War, p.54 Melissa Humphreys - Highlights of Melissa's early life.
- ↑ House Marik (The Free Worlds League), p. 19 - Melissa Humphreys first noted as military governor of Canopus.
- ↑ Handbook: Major Periphery States, p.77 Government & Politics - Melissa responsible for Men's Universal sufferage.
- ↑ 'Handbook: House Marik, p. 23 - Melissa noted being appointed Military Governor.
- ↑ Historical: Reunification War, p. 54-55,161 Melissa Humphreys & Good Neighbors to the Magistracy - detail on reconstruction plans and end of her political career.
- ↑ Handbook: Major Periphery States, p. 78 - Dame Melissa Humphreys noted along with Crystalla Centrella helping MoC prosper.
- ↑ Reunification Wars, p. 186 Rules Annex - Character's special abilities gained while using ATOW RPG rules.


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Leads for General Contractors in Thibodaux
Just when you believed it couldn't get more difficult, there's a brand-new video game around. Prepared to benefit off contractors and also give homeowners ammo making it harder for you to offer tasks.
That implies that when you go on a lead for a kitchen area remodel, you'll listen to about the lovely kitchen area remodel across community they saw online that cost $15,000. They will not show how it looks currently, 3 years later, with wear patterns in the low-cost floor covering, chips and also buckling on the particle-board closets, and the reduced cost kitchen tap dripping.
Buy Home Improvement Leads in Thibodaux, LA
In service, it's all about the cash, which will certainly originate from you. From this article, you can read that Porch "will earn money by charging professionals for market understandings and promotional direct exposure, at a price of $35/month for certain geographic areas within a city, with the capacity for professionals to sign up for multiple geographical areas each time."
If you have a construction-related company, you're the professional. You're the one that is mosting likely to pay $35/month. And also note that it's $35/month per area, not $35/month per professional. Areas as defined by Porch. When you pay them, you get the opportunity to provide a lot more data on tasks, as well as wish that you'll get top quality leads.
Where can you find home remodeling leads in Thibodaux?
There are countless construction-related local business owner in the United States, a lot of which are skilled, enthusiastic tradespeople that like their job but aren't strong on the business side. And also they are even weak on advertising and marketing. They hand their business identity over to others with the hope of a $35/lead (like from Angie's Checklist or HomeAdvisor), or the chance to pay to present their task photos on someone else's web site.
Please– you do not have to do that. Take the time to create your own social visibility. It does not require a lot. Start with the complimentary stuff– claim your identification on Yelp, Vendor Circle, Manta, AboutUs. It only takes a couple of minutes per site and it's free. We covered this in an e-newsletter write-up last January. You can (and also ought to) do it today.
Home Improvement Leads in Thibodaux
I'll inform you exactly how professionals have actually assisted Angie's List. In the second quarter of 2013 alone, Angie's List brought in $59 million in overall earnings, with $43 million of that from service suppliers like you.


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Know more about this business than we do? Cool! Please submit any corrections or missing details you may have.Help us make it right
Oak Forest Elementary is an educational institution that enrolls students in kindergarten through grade five. The school offers classes in computer applications, music, arts and crafts, and special and physical education. It also provides a range of academic programs in science, language arts, social studies and mathematics. Oak Forest Elementary maintains a parent-teacher association that...
Accounting, Athletics, Architectural, Budget, Community, Credit Union, Elementary Schools, Finance
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YellowBot wants to get your input! If you have a comment, find a bug or think of something neat we should do, let us know by emailing us.
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List Five or more of your favorite brands
1. Ralph Lauren
2. North face
3. Nike
4. Coca cola
5. Microsoft
6. Lamborghini
7. Tommy Hilfiger
8. Jordan
9. Chipotle
10. Apple
1. Apple, I got my first iPhone when I was 11-12, I bought the iPhone 4 when it first came out and It could do everything that I wanted and iPhones we're always available at AT&T so I just stayed with iPhones.
2. I've had Nike/jordan brand shoes especially basketball ones since I was a kid, I liked the grip on the shoes and they always felt good on my feet. The designs on each shoe is unique and everyone in my family likes buying Nike/jordan shoes.


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Turning tragedy into triumph through healing.
Waterbury Palace Theater: Purchase Tickets
The CMAK Foundation Presents The Race4Chase. from DMO Films on Vimeo.
Pulling people together through Chase's love for athletics.
Healing our hearts while doing good for others.
Race4Chase Kid's Triathlon Program: Inspiring Health and Achievement
In remembrance of Chase Kowalski, the students and educators of the Sandy Hook tragedy, CMAK strives positive force to inspire community healing through family and children-focused initiatives and programs. By focusing on emotional healing and physical health & wellness, we will positively change the lives of children and their families.
CMAK (Chase Michael Anthony Kowalski) Sandy Hook Memorial Foundation is a 501(C)(3) organization. Contributions to the foundation are tax deductible.
Our Chasing the Music Goal
Thank you for visiting our website to honor Chase Kowalski who we sadly lost in the Sandy Hook Elementary tragedy in Newtown, CT. Chase was an amazing son, brother and grandson who's heart was only filled with love for all the people he touched. He competed and won his first triathlon at six and often ran in local road races.
Chase's passion for athletics has inspired a Race4Chase community competing in his honor and CMAK's pursuit of programs to support youth and strengthen families through health and wellness programs. Race4Chase Kid's Triathlon Program, Chase's Place Family Wellness Center and Pre-school scholarships will help fulfill our mission while preserving Chase's memory.
Join our community, get involved and help reach our goal to spread Chase's love. Together we will turn this tragedy into triumph through acts of compassion, courage and love!
2017 Goal: Expand Race4Chase Kid's Triathlon to 20 locations nationally
March 31, 2017 /
admin /
Make A Comment
Blog, Features, Highlights, Press
The CMAK Foundation is pleased to announce that Dennis House, Emmy award winning Eyewitness News anchorman for WFSB Channel 3 News CT, will be presiding over the Chasing the Music event as Master of … Read More
January 28, 2017 /
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Blog, Features, Highlights, Uncategorized
The CMAK Foundation will stage an exciting new classical music event called "Chasing the Music". Carter and Ilaria Brey and the Kowalski family have become close friends in the aftermath of the … Read More
Race4Chase Boston Marathon Team 2017
CMAK has awarded Heather Theriault from Madison CT and Scott Sartwell from York SC the CMAK charity bibs for the 2017 Boston Marathon under the … Read More
January 28, 2017 /
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Five New Race4Chase Sites confirmed at MOU Signing ceremonies!
CMAK is proud to announce that the Race4Chase Kids Triathlon Program is expanding in 2017 by five sites. CMAK has accepted the … Read More
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Global trade will expand by 2.8 per cent this year rather than the previously forecast 3.9 per cent, the World Trade Organization (WTO) said Thursday, citing slowing economic growth in western countries and various risks that could hurt global demand.
"Business and consumer confidence has slipped recently in developed countries," the Geneva-based trade body said in its latest twice-yearly forecast.
WTO experts added that global exports and imports face several uncertainties this year, including a sharper-than-expected slowdown of China's economy, as well as higher volatility of financial markets and exchange rates, the trade body said.
The downward revision means that trade is expected to grow at the same rate as last year.
"This will be the fifth consecutive year of trade growth below three per cent," WTO Director General Roberto Azevedo said.
He warned that the actual value of global trade has been falling because of exchange rate effects and falling commodity prices.
At 3.4 per cent, Asia is expected to be the region with the fastest growing export volumes this year, followed by Europe and North America with 3.1 per cent each.
Latin American exports are projected to lag behind at 1.9 per cent.
Demand for imports to this region is expected to fall for the third year in a row.
In 2017, the WTO forecasts the pace of global trade growth to speed up to 3.6 per cent.


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Make Your Own Stamps Tutorial
You can carve stamps with a variety of materials, even erasers or potatoes, but this tutorial focuses on what the pros carve stamps with and you can create a long lasting stamp this way that can be used over and over for years to come. The best part is that the materials involved are not costly, so you can practice and still have left overs to make your own stamps.
I adore Staedtler Mastercarve Artist Carving Blocks because they cut so easily and they stamp perfectly. You can draw directly on them with pencil too.
For carving the stamp, this Small Plastic Linoleum Cutter is a great economical set and works really well. I have an older version of this same set and have been using it for a few years now.
Draw your design and then carve away all areas that will not have ink on them. All areas that are white are carved away while all areas that will pick up the stamp ink will be left untouched.
TIP: Remember that whatever you carve will be backwards when you stamp it! This is especially important when carving letters - you'll need to carve them backwards to stamp the right way.
Now that you know how to make your own stamps, here some ideas to put your stamps to use!
Plus, you can even stamp on fabric and wood if you use the correct stamp ink! Use Tsukineko VersaCraft fabric and wood ink on wooden blanks to create amazing wedding favors!
Or, consider buying plain fabric pouches for your favors and stamping them to create personalized favor pouches cheaply!
Carving your own seem too difficult? Have a whole sheet of stamps made for you using this alternative Make Your Own Stamps tutorial!
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Feeling minnesota 1996 full movie stream free online. Sam Clayton's (Vincent D'Onofrio) marriage to ex-stripper Freddie (Cameron Diaz) comes about when she's strong-armed into the match by Red (Delroy Lindo), a club proprietor who once did her a favor. But Freddie falls in love with Jiaks (Keanu Reeves), Sam's brother, and the pair tries to escape the situation together. It isn't long before both Sam and Red catch up with them, resulting in threats against the two of them — although tension also starts to build between Sam and Red.
If you're unable to stream the movie, Please refresh the page by pressing F5 button and try to play the movie!
Published on June 19, 2016 by admin


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my destiny lionel richie with lyrics MP3
i do not own any copyright regarding the music, lyrics or omages in this video, i just put it together.
Lionel Richie - My Destiny lyrics MP3
Lionel Richie - My Destiny with Lyrics Watch, Read, Listen, Sing-along.
Lionel Richie - My Destiny (with lyrics) MP3
Lyrics: http://easylyrics.org/?artist=Lionel+Richie&title=My+Destiny Thanks for checking out our videos and site!
Lionel Richie - You Are My Destiny ( rickyBE Remix ) MP3
lionel richie you are my destiny remix produced by ricky be. One of my very first from years ago with my old equipment. Much improved sound quality on all the ...
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Lyrics: Stuck on you I've got this feeling down Deep in my soul That I just can't lose Guess, I'm on my way Needed a friend And the way I feel now I guess I'll be ...
Lionel Richie - All Night Long (All Night) MP3
Music video by Lionel Richie performing All Night Long (All Night). (C) 1983 Motown Records, a Division of UMG Recordings, Inc.
All Night Long (All Night)
Lionel RichieWell, my friends the time has come To raise the roof and have some fun Throw away the work to be done Let the music play on (play on, play on) Everybody sing, everybody dance Lose yourself in wild romance We're going to party Karamu, fiesta, forever 1 Come on and sing along We're going to party Karamu, fiesta, forever Come on and sing along All night l[...]
Lionel Richie - My Destiny Lyrics MP3
Lionel Richie - My Destiny Lyrics.
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My Destiny - Lionel Richie (with lyrics) MP3
"No copyright infringement is intended"
Lionel Richie - You Are My Destiny MP3
Lionel Richie - Endless Love ft. Shania Twain MP3
Lionel's new album Tuskegee is available now! Preview and download on iTunes! http://bit.ly/LRTuskegee.
Endless Love
Lionel RichieMy love, There's only you in my life The only thing that's bright My first love, You're every breath that I take You're every step I make An[...]
Lionel Richie - Back To Front (Full Album) MP3
00:00 01. Do It to Me 06:02 02. My Destiny 10:48 03. Love, Oh Love 16:42 04. All Night Long (All Night) 20:53 05. Easy 25:10 06. Still 28:52 07. Endless Love ...
Lionel Richie - Just For You MP3
Lionel's new album Tuskegee is available now! Preview and download on iTunes! http://bit.ly/LRTuskegee.
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Lionel RichieGolden days, life was play Pain was all a world away We went to school, we learned the rules We trusted all they had to say Then life took a turn We all had to learn And we can't [...]
Lionel Richie- Say you say me [Subtitulado al español] MP3
Hoola, hice una traducción de esta canción a ver que tal, si les gusta por ahí empiezo a hacer de otras canciones :D espero les guste y me gustaría que ...
Lionel Richie-My Destiny (OFFICIAL AUDIO) MP3
LOVE THE DRUMS You came in That's what my little heart was looking for Laughter in the rain Feeling like a fool in love again The laughter came When the ...
Angel (with lyrics), Lionel Richie.[HD] MP3
I originally uploaded this video in 2010 under my original acct Latinavixn However I've been finding all of my videos stolen & uploaded by a bunch of fake accts ...


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- From the first episode, Tenchi's "Oh, Crap!" reaction when he breaks his ancestor's (really his grandfather's) sword, which breaks the rock that sealed the chamber where Ryoko was imprisoned. Made funnier in the English dub once Tenchi realizes the true impact of his blunder:
Tenchi: I'm giving these keys back to grandpa and do as many chores as he says!
Tenchi: I've just used the oldest trick in the book.
- The entire last third of the episode, starting with Ryoko properly introducing herself, is this, with special mention of Tenchi tricking Ryoko by making her look out the window.
- From episode 2:
Ryoko: Now, I want your balls, please!Tenchi: Huh? (grabs his groin) No way! They're mine, and I'm gonna hang on to them!Ryoko: Oh, you numbskull, I meant the jewels on your sword!
- In episode 4 (one of two Hot Springs Episodes), Noboyuki attempts to get Tenchi to peep on the girls. He's trying to be all sneaky and everything... until he looks up and sees Ryoko looking over nonchalantly and freaking Noboyuki out.
- Ayeka slowly steps into the water to sit with Tenchi, prompting jealous Ryoko to steal her towel.
- A few moments after that, Tenchi's broken away from the feuding Ryoko and Ayeka to recover, only to have Sasami spot him. Seeing his state, she only has one thing to say: "You're a naughty boy, aren't you, Tenchi?"
- Kagato's teleporting onto Earth in episode 5... in the middle of the hot springs Ryoko, Ayeka and Mihoshi are bathing in. In spite of the danger they are in, cue a flustered Mihoshi and Ayeka calling him a pervert and tossing random objects at the guy looking briefly dumbfounded at being ignored as an enemy threat.
- The aftermath of the Single-Stroke Battle between Tenchi and Kagato. Tenchi wins however Kagato's spaceship Soja is ALSO cut in half as well.
- Just about the entirety of episode 7, but the ending deserves special mention. Ryoko and Ayeka attempt to get Tenchi all to themselves by sending Mihoshi back to Galaxy Police HQ and locking Washu in her lab, then setting up a trap on Tenchi's door that sends anyone who passes through it uninvited into the lake outside. However, Sasami defeats the trap by simply... knocking on the door and waiting for Tenchi to let her in, ignoring Ryoko and Ayeka's fighting, telling Tenchi about a really bad dream she just had. Ryoko and Ayeka can also hear Washu inside, so they try to rush in through the door, and get sent into the lake. To top off their Humiliation Conga, Mihoshi returns from Galaxy Police HQ, and crashes her ship on top of them. Seeing as how Ryoko and Ayeka are both Made of Iron, they naturally survive, but the looks on their faces just before the ship crashes are priceless.
- Episode 8 has Washu reveal her past... then attempt to win Tenchi over using her rarely-used adult form!
- Ryoko starts changing Taro's diaper... then she starts poking his penis... then he pees on her.
- Mihoshi trying to calm a crying Taro but when it doesn't work, Mihoshi starts crying like a baby herself. What's funnier is that when this happens the baby does stop crying and starts trying to console Mihoshi.
- Tenchi getting a little overheated (in more ways than one) when he hears Mihoshi in the bath trying to tell Taro not to suckle from her breast.
- Also, when you finally figure out why Sasami was inactive the entire episode.
- Ryoko and Ayeka's exhausted chants of diapers and milk, with the latter eventually drinking out of the baby's bottle.
- One part of episode 9 has Tenchi, Noboyuki and Katsuhito fixing up the roof of the hot springs they wrecked. Noboyuki accidentally smashes his thumb with his hammer, leading to Katsuhito chastising him... before smashing his own thumb. When Tenchi calls them boneheads, Katsuhito's able to distract Tenchi long enough to have him smash HIS thumb.
Katsuhito: Now who's the bonehead?
- The moment where Sasami runs towards and past Ayeka to hug Tenchi instead after she's been reassured about her situation.
- At the end of the episode, even Tsunami could not get a word in on a Ryoko / Ayeka argument. It's not often that you get to tell a goddess to shut up / stay out of this.
- Anytime Aekya and Ryoko fight is both a Crowning Moment of Funny and a Crowning Moment of Awesome.
- Ryo-Oki, the giant super... PINK ROBOT!
- Magical Girl Pretty Sammy!
- The entire scene after Misaki arrives for the first time in the OVA. Gets Turned Up to Eleven after Ayeka's, "My mommy!"
- Ayeka even warns Ryoko not to laugh, or she'll be sorry. Ryoko laughs anyway (complete with Face Fault), and comes face-to-face with Misaki in Mama Bear mode.
- Most of episode 13 qualifies, particularly everything after the Emperor of Jurai's arrival: The entire Royal Family (including Tenchi) seems to await his arrival with the appropriate amount of respect - until he does arrive: The Emperor is pretty much The Comically Serious: his demands for his daughters to return with him to Jurai are ignored, particularly Ayeka due to her constant bickering with Ryoko over Tenchi. Even raising his voice didn't get Ayeka's attention. Even Sasami said she'd never forgive him if she's made to leave Earth. Even Ryo-Okhi's dance in child form to him to make him happy has him initially utterly perplexed until the former starts crying. Funaho comforts Ryo-Ohki, while giving him a look that says "you're being a jerk". Really, the guy completely came off as the No Respect Guy in that episode. Ironic given his status.
- "You're going to get wet." Splash
- In the manga chapter on Mihosi's driving lessons, a student driver and his teacher freak out and crash when they see Ryoko emerging from a traffic sign.
Funny / Tenchi Muyo!
The OAV series Tenchi Muyo! (not to mention the spinoffs and sequels), has plenty of moments.


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What is JotForm?
JotForm is a free online form builder which helps you create online forms without writing a single line of code. No sign-up required.
At JotForm, we want to make sure that you're getting the online form builder help that you need. Our friendly customer support team is available 24/7.
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Can I set a field to display a minimum amountAsked by hughdal on July 30, 2015 at 07:01 PM
The field "cost for each print" I would like be a minimum $5
So if the calculated cost works out to $4.95 it displays $5.00
Same if the calculated cost works out to $1.00 it displays $5.00
JotForm Support
You can add another "Cost for each print" field then conditionally fill it based on the first "Cost for each print" field value. Here are the conditions:
You can hide the other "Cost for each print" field so it's not visible in the form.
I've cloned your form and made these changes. Here's the link for you to view it: http://www.jotformpro.com/form/52109458816965.
You can clone it back by following this guide: https://www.jotform.com/help/42-How-to-Clone-an-Existing-Form-from-a-URL.
Just to note up, don't use a $ sign in the equation because that would cause a problem in the calculation. You're adding it as a text instead of a number.


text:
Ann W. Caldwell President's Lecture: Interprofessional Rounds
The Ann W. Caldwell President's Lecture: Interprofessional Rounds is an annual event in which second-year students in the entry-level graduate programs come together to hear successful examples of how clinical teams collaborate to provide patient-centered care. Named after the MGH Institute's fourth president (1997–2007), the lecture is intended to reinforce the school's mission to prepare health professionals to advance care for a diverse society.
The theme of the 2017 Rounds was "Caring for Our Muslim Patients." Heba Abolaban, MD, MPH, Ahmad Al-Moujahed, MD, and Robert P. Marlin, MD, PhD, MPH, presented.


text: Romulan Rank Insignia Rank Insignia Rank Name Rough Federation Equivalent Admiral Fleet Captain Commander Captain Sub-Commander Commander Centurion Lieutenant Commander Lieutenant Lieutenant Sub-Lieutenant Lieutenant Junior Grade Uhlan Ensign Retrieved from "http://scratchpad.wikia.com/wiki/Romulan_Rank_Insignia?oldid=187444" Ad blocker interference detected! Wikia is a free-to-use site that makes money from advertising. We have a modified experience for viewers using ad blockers Wikia is not accessible if you've made further modifications. Remove the custom ad blocker rule(s) and the page will load as expected. Categories: Starfleet Intelligence: Section 31 (RPG)