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Religion and Theology
The purpose of Dante's journey
The purpose of Dante's journey - Research Paper Example
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The purpose of Dante's journey
As such, the story is heavily influenced by the Catholic teachings during his time (the Medieval period) as shown by belief in these three states as well as an earth-centric view of the universe (before a more correct one was discovered by Copernicus and proved by Galileo which is helio-centric, for which he was forced to recant under pain of death during the period of the Inquisition) as evidenced by the story's placement of Hell at the center of concentric circles that was more or less consistent with the Ptolemic conception of the universe at that time. The story of his journey is an allegory that tells of his resentments at being forced to live outside his country (exiled) due to numerous political enemies who betrayed him. But the story of "Divine Comedy" has many other allusions to more crucial or important things in life that really matter the most such as loyalty and trust. Further evidence of the other aspects is a reference to the people who cannot decide their minds and practice fence-sitting to wait and see who wins in a political struggle before they will make their own stand known. In a sense, Dante's work is a stinging indictment of the people he had met during his lifetime but offers a redemption for some although a more potent message in this story presented as a collection of poems or songs is that punishment must fit the gravity of the crime committed. ...
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Student's Name: Professor's Name: The Purpose of Dante's Journey (word count = 2,230) 29 July 2011 Introduction This paper examines the work of one of the greatest Italian writers ever who wrote the literary classic, the "Divine Comedy" which tells the journey of the author, Dante Alighieri…
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Birthday cake donuts make a fun alternative to the traditional birthday cake. Frost them, add sprinkles, or decorate them in any way that will suit your teen's personality.

Cake pops can be used to replace the birthday cake or simply use them as party favors. Color coordinate them with the theme of the birthday party or create a variety of flavors. You can even make cheesecake pops, brownie pops, and peanut butter and jelly pops.

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There's no reason a cheesecake can't double as birthday cake. Top traditional cheesecake with fruit or try a specialty cheesecake - like peanut butter swirl. These mini canning jar cheesecakes make perfect birthday party options.

Decadent whoopie pies are a delicious alternative to a birthday cake. Decorate the icing with brightly colored sprinkles for a little birthday flair, or make gourmet flavors, like red velvet.

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Although at first glance, Sweet Ballz resemble cake pops, there's a secret to Sweet Ballz - they're store bought. A mixture of cake mix and icing dipped in more icing and topped with sprinkles make these delicious little treats look like you spent hours in the kitchen. Currently available at Costco, you can build them into a pyramid or simply serve them on a platter. They stay fresh for up to a year in the freezer or up to 60 days thawed so it's safe to buy them ahead of time.

What teen doesn't love chocolate, ice cream, and chocolate sauce? Use a store-bought chocolate cake mix to create a two-layer cake. Fill the center with chocolate ice cream. Top with whip cream and chocolate sauce. Sprinkle with your favorite toppings such as cherries, chocolate chips, or nuts and your super-chocolate sundae cake bar will be complete.

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In addition to being surrounded by some of the most extraordinary scenic treasures anywhere in the world, we enjoy all the benefits of a supportive, rural community, progressive educational standards and state-of-the-art facilities. We hope you'll take some time to browse through our website and find out more about our district and what we have to offer our students, employees, and our community. If you have questions, we hope you'll contact us directly.
Whether you need to know about student registration, employment opportunities, or some of our local scenic attractions, we're sure our website will provide you with the information you need. So, thanks for visiting Page Unified School District's website and enjoy your stay!
"Collectively Committed to Every Student, Every Day, Every Minute"
Mission Statement:
The mission of the Page Unified School District is to provide each student with a challenging academic education in a caring and safe environment.
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A focused commitment to providing Arizona's Greatest Education
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Nondiscrimination Statement
Welcome to Page Unified School District, a culturally diverse community of learners. We are honored that you have chosen our district to educate your children. For the 2016-2017 school year our teachers, principals, and staff have dedicated themselves to provide a comprehensive, world-class education for all students. We believe that all children can learn and we are here to partner with you, our families, and community to help our students find success in every area of their lives. We invite you to become an active participant as we work to become one of Arizona's best school districts.
There are many ways for you to obtain information regarding Page Unified School District. Please give us a call at 928-608-4100 or visit our website where you will find information about our schools, programs, and how to volunteer in the district.
I want to thank each of you in advance for your assistance in creating an environment that is both nurturing and caring for our students. I am excited to join Page Unified School District and am looking forward to a growing partnership with our parents, communities, staff, and students.
Rob Varner, Ed. S.


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How do I become less ticklish?
Actually how do I make me body less sensitive to touch altogether?
Most Helpful Guy
Yes I AMMMMMMMM ticklish. And unfortunately there really isn't any way. People say mind of matter but that's bullshit haha. Sorry we're stuck this way.00|00|0
Most Helpful Girl
I'm very ticklish and so are many people. In fact laughing because of tickling is a defense mechanism. There's no real way to become less ticklish. Actually you feel stuff including tickles by your afferent neuron receptors (sensory neurons). For example, in pain the nociceptors (pain receptors) are the nerve endings of afferent Aδ and C nerve fibers. But anyway you can make your body less sensitive very easily by destroying some of those receptors located in the dermis of the skin. For example you can burn your hand and that way the nerve endings will be destroyed. In fact, because you will have destroyed the nerve endings, you will not feel any pain. So it's a win win.
Note: Please don't burn anything that was a joke.64|20|0
Upvoted because I didn't understand a word of that.
- Show AllShow Less
@redeyemindtricks I was assuming she didn't have any imbalances (many people are ticklish without any deviations from the normal vitamin levels) but never heard of the brush method haha
The Wilbarger method was developed for kids on the autistic spectrum (who often have EXTREME tactile defensiveness -- the brushing is something that's basically needed just to get them to the point of being able to deal adequately with the normal tactile sensations of everyday life)... but, it can still have at least marginal benefits for non-autistic people who are just more sensitive than average.


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Fandom Mashups: August 6th
Posted on August 6, 2017 by battybibliophile
This is a weekly meme created by Lunar Rainbows. Every week there's a new scenario and you choose 5 characters from 5 different fandoms to complete the task. The topic this week is: A night a magical fireworks is on the agenda … Continue reading →


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Welcome to the Community
Department Rental Facilities
|Because we care, we want to welcome you to the community.
|Pfluger Hall is deeply rooted in the Pflugerville community and provides a venue for gatherings and celebrations whether it is a once-in-a-lifetime event.
The following education pieces are part of our Growing Forward journey in support of our mission to serving the community.
The Department Growing Forward
Response Goals
|Travis County ESD No. 2 / Pflugerville Fire Department is the busiest Emergency Services District (ESD) in the county with... Click here to download.
|There are numerous state and nationally recognized organizations that set and measure performance of departments that... Click here to download.
Day in the Life,
Road Map to the Future:
|While the characteristics of professionalism, compassion, and bravery are core to a firefighter... Click here to download.
|The District runs projections for future planning. Recent projections show if we project that the economy remains slow... Click here to download.
Stretching a Dollar and
The District's cost to provide fire and emergency medical response services is higher than the property tax revenue we receive per capita...


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Home > Community > Health Library > Animal Dander
Animal dander is loose skin cells (like dandruff) from animals such
as dogs and cats. These skin cells, which contain secretions from glands in the
animal's skin, float in the air, where they may be breathed in by people.
Animal dander is an allergen. Animal fur or hair is not an
allergen. When a person is allergic to an animal, such as a dog or cat, the
allergy may be to animal dander (skin cells) or to dried saliva from the hair
of a cat.
Current as of:
February 12, 2016
Healthwise Staff
Medical Review:
E. Gregory Thompson, MD - Internal Medicine & Adam Husney, MD - Family Medicine & Rohit K Katial, MD - Allergy and Immunology
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When do you think the 'defining the relationship' talk should come up? I know that each situation is different (ie. two couples could both be together for 4 months, but one couple sees each other 4x a week vs. the other couple only sees each other 1x per week). Can a couple say they are 'in a relationship' when they are going out for a couple of months, but see each once 1x per week?
Most Helpful Girl
I dont think it needs to be a big deal.
When I felt ready I just told my SO "I'm not seeing anyone else. Just checking we're on the same page." He said yep and that was it.11|00|0


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I recently did a walk-through for a local consignment store and she is in dire need of an upgrade. She is currently running her consignment software (Liberty4) on a Windows XP machine and isn't backing it up. I spoke with the company who makes the software and they seemed out of the loop because they haven't even tested it with Server 2008 R2, but was told it should work. Also, she uses SQL Express, but since they will be adding more machines they recommended going to at least SQL Server 2008 R2 Workgroup because it would max the memory on Express. Basically I have to test all this out before anything is even implemented to make sure it works.
Her network equipment is also all consumer grade and is gobbled together. She currently has 7 computers and will be adding another. I'd say 90% of the machines are running Windows XP Professional and they are all custom built (YUCK). I will slowly upgrade each machine over the course of the year.
Below is a list of devices I've informed her she should be buying. I was going to sell her GFI Backup, but I was just notified they are discontinuing it so I need to find a different onsite backup software. I might just stick with the built-in backup because even going with Acronis Server it is over $700. All it needs to do is do incremental back-ups and a system image.
Server: HP Proliant ML110 G7 Server (need to buy hard drive trays)
Hard Drive: Samsung Spinpoint F3 1TB (2 of them in RAID 1, can't do 4 way too expensive)
External Hard Drive: Western Digital 1TB USB 3.0 portal hard drive
Onsite Backup: ??????
Offiste Backup: CrashPlan Pro
OS: Windows Small Business Server 2011 Essentials (OEM)
SQL: Microsoft SQL Server 2008 R2 Workgroup (additional CAL's need to be purchased)
Firewall/Router: Sonicwall TZ 100 with Wireless-N
Switch: HP Procurve V1910-16G (smart) or 1410-16G (unmanaged)
Let me know if you have any other suggestions.
10 Replies
Feb 5, 2012 at 1:57 UTC
Internal I.T. Ltd is an IT service provider.
Switch go with the 1410. It's a simple small networks their in nothing you need from the 1910
You should not need to buy SQL. I have a client running MS NAV Dynamics on SQL express 2008 R2 and they have 20 work stations.
I'm pretty sure Crash Plan has the option to backup to en external drive. If not. Todo Backup has a server version that support SQL for $300
That's my 2¢
Feb 5, 2012 at 3:24 UTC
Given the information in regards to her shop, I wouldn't be too worried about going with all the higher profile options-
whitebox terminals are fine, just make sure software versions are consistent and patched. check hdd smart status and ram. get processors and establish a baseline bare minimum.
a single server should be fine to handle this, and running sql express shouldn't be an issue- these are pos systems (yes I know, technically both meanings of the term)
OS wise... If win7 configured with every pretty shut off (which it should be, screw aero) will run, go for it. I might upgrade her whiteboxes just to make sure they can all run it.
For her server os, again... I wouldn't do anything serious. it's not needed.
the managed switch is nice (always nicer than unmanaged) but again, unless her business is looking to expand drastically, I wouldn't bother.
Feb 5, 2012 at 10:17 UTC
Internal I.T. Ltd is an IT service provider.
As far as os ther is server 2008r2 foundation. It is pretty much the full 2008r2 but limited to 15 users
Feb 5, 2012 at 10:26 UTC
Yeah I don't see them needing VLANs and the unmanaged is only $150.
As far as the SQL issue the guys at the company kept saying you will have to move to a SQL Workgroup, etc, etc. I could possibly try out SQL Express 2008 R2 and see how it runs and if worse comes to worse, she'll have to buy Workgroup.
For backup, I was looking at Yosemite (I'm a Barracuda fan). For the SBS license it is $399 which isn't terrible and it does Bare Metal/SQL/etc. It might seem like overkill, but this lady does quite a bit of business and her data is extremely valuable. Also I need something for her that if something does happen, I can give her steps on how to do recoveries since I do this all on the side.
Reason I went with SBS 2011 Essentials is because it's under $350 and she is in need of a domain environment. Most of her employees are high schoolers and she's had issues with them downloading software, surfing the web etc. Reason why I picked the TZ 100 with the suite for content filtering.
If she wouldn't need to pick up 2008 R2 Workgroup that will save her a slew of cash which she'll like.
Feb 5, 2012 at 10:38 UTC
I have no background here, but are there certain security requirements for credit card purchasing? If you are making upgrades make sure that the system is designed with these rules in mind.
Also look into any productivity or time saving services that could help on the retail side too (bar codes, inventory control, wireless, etc.) Provide a good platform for the shop to be able to take the next steps...
Feb 5, 2012 at 10:45 UTC
The credit card transactions aren't being done over the network. As far as POS stuff, I told her she should work with someone who deals with that on a day to day basis since I don't.
EDIT: Yosemite Backup seems to be out of the picture. Looks like you can't do a full-disk backup to a USB external hard drive. This is right from the manual:
You may not perform disaster recovery to a USB hard drive or to Fibre Channel devices .
Feb 5, 2012 at 2:29 UTC
If she does that much business, maybe she needs to hire you for a bit more than on the side :P
It's nice to see that someone out there is actually having a good run business wise.
Feb 5, 2012 at 3:40 UTC
I do this all on the side. I'm the Sys Admin for a System Integrator company and on the side I do a bunch of projects. This is one of them.
Feb 5, 2012 at 8:29 UTC
Power Users, LLC is an IT service provider.
For manageing the workstation upgrades, implement a FOG server and use this guide. With it, you can push out 10 images in less than 20 minutes (with proper configuration) and save you from ever installing windows on the network again.
For onsite backups, try Cobian 10. It's free, encrypts your data, can send it offsite (if you want), has compression, emails logs, no ads, and much much more...again, for FREE. Dont use NTbackup.
You might also consider looking into Shadow Protect for the server. It has the ability to bring up a failed SQL/Exchage/AD (whatever) server in less than 5 mintues after complete failure. We use this product on EVERY single one of our servers (except Linux servers...but soon) ...because it is our product! but also because it's the best on the market and we trust our own product.
Feb 6, 2012 at 10:00 UTC
I'm not too worried about the workstations. I was looking into ShadowProtect and it's just a tad bit more than Yosemite Backup. I'm waiting to hear back from Barracuda about Yosemite and the ability to backup the system to USB drive and restore from that.
I've been dwelling over the weekend to possibly do this in stages, because I know the lady won't like the upfront cost. I might just bypass the security subscriptions all together for the Sonicwall and just get the TZ 100 with wifi and support and use OpenDNS for the filtering. I will just have to statically assign the machine that needs access to Facebook to use a different DNS.
This discussion has been inactive for over a year.
You may get a better answer to your question by starting a new discussion.


text:
Report summaryMarsa is a an underground vein gold mine exploited by a conventional over cut and fill mining method. It operates a 1.8kt/d processing plant. This plant includes a flotation circuit and a Merrill Crowe circuit. The saleable product is the Au-Ag precipitate.
What's included?
This report includes 2 file(s)
- Retamas gold mine PDF - 494.53 KB 7 Pages, 1 Tables, 1 Figures
- Retamas gold mine XLS - 139.00 KB


text:
Bridal Shower Cake- Will This Look Ok?
Decorating By JenniferL Updated 22 Feb 2008 , 10:59pm by JenniferL
My friend is having a bridal shower this weekend and their wedding has an outdoorsy springtime theme. For her cake I was planning on making a cake similar to this one by cheekysweets:
What I am thinking is that I will make the square cake and ice it with green bc and then use royal and bc flowers in pink, purple, white and peach for the accents. I wanted to trim out the bottom with the extra flowers and some bc grass (the grass tip is my FAVORITE icing tip! ) The dress would be covered in white fondant, but I wondered about wrapping a small piece of pink or peach fondant around the waist to tie in the color of the flowers.
Do you think this would look ok or will it be too much green? (Her bridesmaid's dresses are green.) Should I use the grass around the bottom or just a shell border? Does anybody have any other suggestions?
Last question- what size pan do you think I would need for the bottom cake? I was thinking 10" or 12"? I pm'd the cheekysweets, but haven't heard back yet and I've got to buy my ingredients tonight.
Y'all are always so helpful so TIA!!
whether you use a 10' or 12' would depend on how much cake you need. The both provide a lot of servings.
Your plan sounds nice, but consider the consequences of all that green color- green lips,teeth etc. I think green accents or trim would be good enough.
I think that using ribbon around the waiste would be better than fondant because if you dont like the look, you can remove the ribbon without damaging the dress, were as fondant may do that and leave an eye sore.
Those are great ideas. The 80 year old women there might not see the humor in green teeth! When they lift the bride off of the cake, her dress won't look as messy either.
I could even try the ribbon first to see if I'm going to like it and then use fondant.
Thanks for your suggestions! I would appreciate any suggestions that I could get!!
so...a 10" square (2- 2" cakes torted and filled) will feed aprox. 50 people?


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Marginata (Dracaena marginata) - Plant
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Description for Marginata (Dracaena marginata)
Dracaena Marginata, is a popular indoor plant originally from East Africa that is often used to adorn homes and offices.
These are some of the best house plants and make great additions to any home while requiring minimal care. Bright indirect light is best and they will take some morning sun. Most Dracaena will tolerate lower light levels for some time with reduced watering frequency.
|Common name
|Flower colours
|Bloom time
|Dracaena marginata, Red-edge Dracaena or Madagascar dragon tree,Dracaena deremensis.
|Summer flowering
|6 to 10 feet
|Easy to grow.
Planting and care
The best way to grow dracaenas is to buy a small one from us and plant it in a simple pot. After that, the necessary care is very simple. Plants that are dark green usually require less light than those that have any kind of colour in their leaves. The less light a plant has, the slower it grows. The slower it grows the less water and fertilizer it needs.
|Most of those in the Dracaena genus including the Corn Plant do best in light shade or gentle filtered sunlight.
|Loose, well-drained potting mix.
|In lower to medium light, water dracaena marginata when the potting soil has dried almost to the bottom.
|28 to 38 degrees C
|Fertilize lightly at the beginning of spring or twice a year with controlled-release fertilizer.
Caring for Marginata
- D. marginata is sensitive to fluoride, which can cause discolouration.
- Water with distilled or non-fluoridated water.
Typical uses of Marginata
Special features: Container or above-ground planter; border; suitable for growing indoors; accent
Ornamental use: Used as indoor plant in home and offices.
- http://edis.ifas.ufl.edu/fp186
- http://www.wikihow.com/Grow-Dracaena-Marginata
- http://www.gardeningknowhow.com/houseplants/dracaena/dracaena-houseplant-care.htm
- http://www.plantandflowerinfo.com/plant_care_dracaena


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Chad Johnson was born on January 9, 1978 in Miami, Florida, USA as Chad Javon Johnson. He is an actor, known for American Reunion (2012), NFL Cheerleader Playoffs (2006) and Dancing with the Stars (2005). He was previously married to Evelyn Lozada. See full bio »
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Image: Higher Learning (1995)
It's difficult to offer general advice on the adviser-advisee relationship because it varies so much — by discipline, professor, student, or institution. How friendly, how hierarchical, or how useful the relationship is differs from one pair to the next.
Still, there are some near-universal implicit rules that govern this relationship. More often than not, a student learns them the hard way.
As a director of graduate studies, I can offer some general words of advice for students on how to navigate this critical relationship. Because, despite all the differences, there are some implicit rules that are near universal about these relationships and that graduate students, more often than not,end up learning the hard way. This post will uncover some of those implicit rules and help students start off on the right foot.
Ask us to explain our expectations. Many a relationship runs afoul of unstated assumptions. I ran into that trouble myself with an implicit rule that I didn't even realize I had — until a student didn't follow it. Turns out, I expect new(ish) graduate students to spend a majority of their working time on campus — usually from around 9 a.m. to 4 p.m., four days a week. If students want to work from home one day a week, that's fine, but I want to see their faces around the office. Once trust has been established, I am more flexible.
Unfortunately, I did not explain my expectation clearly to one of my students, and that left both of us frustrated. To avoid such conflicts, you might want to ask your adviser for clarifications on the following:
- Work schedule. How much does your professor expect you to work on campus (or off)? What about over the summer?
- Emails. How quickly does your adviser expect you to respond to messages?
- Tasks. How quickly does your professor want you to complete work?
- Interruptions. Is it OK to stop by your adviser's office uninvited with questions? When is it not OK?
I am not saying that advisers should call all the shots here. I am saying that you need to have explicit conversations about our expectations. That allows you to either: (a) meet them, or (b) negotiate to come up with an agreement that works for both of you. My student and I should have talked and set up a work schedulewe could both live with.
Respect the demands on your adviser's schedule. Professors are busy. Graduate students are too, but you tend to have more flexibility in your day.As a general rule, when you are trying to schedule a meeting with your adviser, defer to his or her schedule. That's even more important if your adviser is an administrator, because someone in an administrative position is likely to have a highly scheduled workday.
Don't try to our friend. The boundaries between adviser and friend are complicated. In one sense, you want to be friendly with your adviser. But you shouldn't be friends — either on social media or otherwise — until you graduate. It is hard to be critical of a friend, and your adviser may hesitate to give you crucial feedback if you are too chummy. In fact, The Professor Is In's Karen Kelsky cites this as one of the top five traits of the worst advisers. You want someone who can help you become a better scholar and researcher, not go to a movie with you. I look forward to friending my students on Facebook once they graduate, but I am not going to do it before.
Respond to emails promptly and politely. If your adviser emails you, please at least acknowledge — ideally within less than 12 hours — that you got the email. Even better, say thanks if the email was helpful. I emailed a graduate student with some information related to that person's next career goals, and never received an acknowledgment let alone a thank you. You can bet I was irritated. In or out of the academy, that's just common courtesy. So make sure you take the time to say thanks after a faculty member has helped you, especially your adviser.
When you meet with your adviser, have an agenda. Make a list of questions you want to ask, updates you need to give on particular projects, and any other information you want to share. During my last few years of grad school, my adviser was an administrator and, thus, very busy. Each time we met, I would bring with me a bulleted list of what we needed to discuss, and work my way through it. That cut down on the number of emails I had to send and times I had to pop into his office.
Actually take our advice. When we tell you to do something — make certain editing changes, fix the references in a paper, shorten a section — it is super irritating when you come back to the next meeting having not done it. Given our experience, we as advisers usually have good reasons for telling you to make certain changes. If you don't make them, come to our next meeting prepared to explain why. Perhaps something came up? Or maybe you didn't agree with the change? But don't send us the same unchanged manuscript without some kind of comment.
Google it first. If you have a question about something that someone else may have the answer to — i.e., a coding problem, an analysis issue, or an APA style question —trying using a search engine before you approach us for help. In countless meetings, I've had students ask me questions they could have found answers to on their own. And check Google Scholar, too. Sometimes students will come to me and say, "I want to do my thesis on X. There hasn't been anything done on it." Then I search for X on Google Scholar and find an entire literature. Do your homework.
Go to the right source for the right question. Your adviser does not have the answer to every question. If you have an HR question, you are better off going to the HR office. If you have a question about deadlines, the grad-school website is the place to go. Alternately, your department may have one of those all-knowing staff members who keeps the place running. When I was in grad school, we had Mary Jo, who knew everything and had the answer for just about every question that wasn't related to our research topics. I don't think anyone would have graduated from our program without Mary Jo.
Go to events we mention. If your adviser tells you about an event or a talk, or forwards you an email with a "this looks interesting" message, that usually means you should go — especially if you rarely get messages like that from your adviser. If you are confused about whether to go, move to the next point.
Ask for clarification. This is may be the most important piece of advice. When you aren't sure whether you have to go to an event, just send a reply that says, "Just to clarify: Is this something you would like me to attend?" Likewise, if you are confused about some issue that is impeding your progress on a project— and you've Googled it and talked with fellow students and are still confused — then ask your adviser for clarification. Otherwise, at your next meeting, the task that you were supposed to have completed may be delayed because you didn't speak up. Following this advice also can help you learn and meet your adviser's expectations.
Send materials 48 hours in advance. Don't send a document that you want us to comment on at 9:45 a.m., if our meeting is at 10 a.m. If you are behind and don't have a draft done 48 hours beforehand, admit it and ask to reschedule the meeting. For example, you can say, "I know we are meeting on Wednesday but I still have a few hours' work to do on it. Any chance that I can send it to you tomorrow before 5 p.m., and you would have time to read it before our meeting? If not, could we move our meeting to later this week?"
Keep track of your deadlines. Your adviser most likely does not know the deadline for when you must defend your thesis to graduate in a given semester. We also probably don't know conference deadlines. Take it upon yourself to keep up with those deadlines, and remind us as they approach. If you need a recommendation letter by a certain date, or a document signed by a certain time, make sure you give us plenty of advanced warning and email us as the deadline gets close: "Just a friendly reminder, the recommendation letter for this award is due in one week." That will keep it on our radar. One of the worst situations I have been in was when a student needed a letter for the National Science Foundation Graduate Research Fellowship and my colleague did not turn it in on time. All the effort she and I had put into crafting the application was for nothing. So remind us, especially when it comes to letters for grant applications, which often have hard deadlines.
Give us what we need to help you. If you need a recommendation letter, give us a copy of the announcement for the award, fellowship, or job so that we can tailor the letter to that purpose. Also give us the latest copy of your CV, and perhaps even a few points that might be important to emphasize in the letter.
Confirm what you need to do next. As you are leaving a meeting with your adviser, make sure you understand what is expected of you by the next meeting. You can even email us afterward to confirm our expectations. That is a great way to stay accountable. You do not want to get to the next meeting missing something you were supposed to have done because you did not know you had to do it.
Take notes. I will be at meetings with my students and I will be telling them some kind of important instruction when I notice they are just sitting there kind of looking at me. So I will say, "Don't you want to write this down?" Memories can be lousy. So take notes. They can also help you with the previous point in clarifying what you need to do next.
Don't limit yourself to a single adviser. Kerry Ann Rockquemore has long advocated that graduate students should have multiple mentors. Besides your primary adviser, you might cultivate a mentor on teaching, and one on writing. You might have a mentor who is not at your university but is doing work in a related field. If it turns out that your adviser is out of touch with reality, your informal mentors might be your saving grace.
Keep us posted. Recently I met with a student to discuss the status of our various projects. I was confused about why she seemed so worried about getting one of them done. Then I realized: It was due a few weeks after her wedding and honeymoon. Oops! I had totally forgotten about her impending nuptials. So please — when we're trying to set realistic goals and expectations — talk to us about all of the things you have on your plate. We may have forgotten the large amount of grading you have to do for that online course, or that you have a family obligation coming up.
That advice is not limited to things that are taking up your time. I have had students come and talk to me who were not making progress, and when we really started talking, it turned out they were feeling depressed, anxious, and/or overwhelmed. This next point is so important it deserves special emphasis: Your well-being is FAR more important than any activity or expectation related to graduate school. When my students bring up problems like this, we can usually brainstorm ways to take some things off plate, and prioritize projects.
Graduate school can wait if you are having mental-health problems. Tell us — if you feel comfortable doing so — when you are struggling with physical- or mental-health problems. If you do not feel comfortable telling us, then talk to your graduate-studies chair. And if you do not feel comfortable at all discussing these issues with people in your department, go to your university's counseling center.
Following these strategies early on may help you avoid problems later. But keep in mind: General advice may not be enough. You might also seek out advice specific to your own adviser, graduate program, or field. Identify a recent Ph.D. or a current student who had some success in your doctoral program. Even better, talk with people who actually have worked with your adviser. What do they suggest?
A version of this post originally appeared on Adventures in Human Development and Family Science.


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Tech News on G4
Mario Maker just Super
Sept 9, 2015
By John Powell - G4 Canada
back to -|- Tech News index -|- John Powell column archive
Celebrating Mario's 30th anniversary, Nintendo is now putting the power in the hands of fans. With Super Mario Maker, you can create your own crazy, zany Super Mario levels and share them online with other fans.
The creation tool itself is not only very intuitive and easy to use (point, click and drag) but contains the look, elements, bonuses and mechanics from Super Mario Bros., Super Mario Bros. 3, Super Mario World, and New Super Mario Bros. U.
Just because the tool is simple though doesn't mean it is vastly limited. There are all manner of neat tricks which allow you to manipulate the different elements. One of the more popular techniques is to stack Goombas or Koopas on top of each other so they move in a marching phalanx. Give Mario a shell helmet, put almost anything you like in a question box even an enemy (just grab the item and drop it in), create gigantic enemies (attach a mushroom to them) or make anything fly (just give them wings).
There really are no limits to what you can create except maybe when it comes to the vertical and horizontal borders of your levels. Some jokers of course push things to the limit and create truly impossible levels. That's not a problem though. In the various modes, Mario Maker lets you skip those levels if you so desire and the one stipulation of uploading a level in the first place is you have to have completed it as a player yourself.
When you want to take a break from designing your next masterpiece, you can play 10 Mario Challenge or Course World. In 10 Mario, you are given 10 lives to complete eight pre-designed courses. Some are relatively easy such as one in which you just need to sneak past a floating column of Boos and some are more complicated and difficult. The good news is you can win back the lives you have lost and any new courses you clear are added to your list of designer templates.
Course World is the repository for everyone's creations. Within it is the 100 Mario Challenge. Similar to the 10 Mario Challenge, you are allotted 100 lives to clear eight courses. The courses are pulled from the list of creations uploaded from all over the world. If there is a course that is far too challenging or just flat out impossible, you can skip it for a new one but the choice will cost you a life. As long as other players keep creating though, you will have new levels to play, rank and comment on. Just like 10 Mario Challenge, you can win back lost lives too but you can never exceed the 100 limit.
Also if you happen to own any Amiibo figures you can scan them in. Doing so will unlock and add new elements for you to enjoy and use.
A gift that just keeps on giving, Super Mario Maker provides fans with the satisfaction of dreaming up their own concepts, sharing them with the world and the only true boundary being the limit of their imaginations. Super Mario Maker may not make anyone into the next Hideo Kojima, Tim Sweeney, Roberta Williams or Shigeru Miyamoto but it might give them a new-found appreciation for the art that is game design and development.
Super Mario Maker
Rating: 8 / 10
|Related Articles
About G4 in Canada
G4 Canada (formerly TechTV Canada) launched in September 2001. G4 is the one and only television station that is plugged into every dimension of games, gear, gadgets and gigabytes. Owned Rogers Media Inc., the channel airs more than 24 original series. G4 is available on digital cable and satellite. For more information, see www.g4tv.ca.


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Enque WP Native Media Uploader for Featured Image
OK, trying to get this plugin to work correctly so my clients can use it for their sites, to simplify the confusion of the Admin backend.
A few important features needed:
1. The Tag field does not pull in the previous tags like the backend does. This causes users to create multiple tags that should be the same. ie: chevy & Chevy… Would really help if these can be pulled into the front, just like they are in the backend when creating a post.
2. The Upload Image for the featured image. This should enque the Native WordPress Media Uploader as well…. In most cases, the images needed are already in the media library, and why not cue it anyways? It's much better than the default browser file uploader.
3. Login-Redirects. Currently, I have to add another plugin to create a more smooth transition for users who login by creating a custom user redirect to their dashboards.
4. Admin users should see all posts created by all users of the site.
5. The "Edit Profile" page does not feed in most of the WP 3.6 fields (google+ profile, Social Networks, etc..)
6. Need the option to disable the plugin for pages. Its ok to have that ability, but would be ideal to have a button to deactivate the plugin for editing pages. I am currently using Plugin Organizer to deactivate the WP User Frontend to stop bloggers from editing pages. I've also bumped down the user roles to hide the edit button, since I do need to have the edit button open the post in the WP User Frontend editor..
Besides that, this plugin is a great start. Hopefully looking for more perfecting the simple functions, and not so much for the post-payment features, although, its a great idea. If these features can be fixed, I will definitely buy the Developers license.
- The topic 'Enque WP Native Media Uploader for Featured Image' is closed to new replies.


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Reindeer Hat by Mary Jane Mucklestone
Welcome! You are browsing as a guestWould you like to see 20 projects made from this pattern and much more? create a free account What am I missing?
© Simon Pask
Reindeer Hat
Reindeer (motif 67, page 86) march around this retro-inspired hat while
snowflakes (made from elements of motif 126, page 120) sprinkle from
above. A great project to practice a challenging non-symmetrical pattern motif, the only shaping occurs when the colorwork is finished.
For more information, see: https://www.interweave.com/store/150-scandinavian-mo...


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The second master bedroom, with queen size bed also has en suite facilities, featuring a walk-in shower. This bathroom also leads out onto the pool deck, giving easy access for those necessary 'visits' when you have wet feet!
There's a third bedroom with a full size bed that has the use of the 3rd bathroom and two further twin bedrooms share the fourth bathroom. The open plan kitchen is fully equipped with all the modern conveniences and a full laundry room gives you a washer, dryer, iron and ironing board. With a large living area and a formal dining area there's more than enough room for 2 families to share this house without falling all over each other.
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text:
Sculpture picked for high-traffic Oak Park corner
'Arched Rings' will dress up Harlem and Ontario intersection
Don't be surprised if you see a bright red ball of rings pop up on the corner of Harlem and Ontario in the not-too-distant future.
After a brief competition over the last few months, Oak Park has finally picked a sculpture to place at the high-traffic intersection near Trader Joe's. Dubbed "Arched Rings," the piece — created by Oak Park artist Patrick McDonald — is about 10 to 12 feet high, 6 feet wide and constructed of red painted steel.
Village hall started the contest back in November, looking for sculptors to dress up the corner. Developer Whiteco Residential had agreed, when they built the multistory apartment building on the corner, to contribute $30,000 toward the piece of public art.
Altogether, 26 artists submitted to the contest. The Oak Park Public Art Advisory Commission whittled the field down to five, and held a public vote on the finalist. The commission agreed with the public's pick, and the village board is set to approve "Arched Rings" on Tuesday night.
"Some people may not like its bright, bright color, but it stands out against the comparatively neutral-to-grayish background there," David Sokol, head of the commission, said Monday.
Oak Park hopes to have the sculpture installed by late May.
Reader Comments
7 Comments - Add Your Comment
Note: This page requires you to login with Facebook to comment.
Nancy from Oak Park
Posted: February 27th, 2011 11:39 AM
Whose brilliant idea? "Art" though it may be, it's foolish to add a distraction which will compete for drivers' attention on Harlem Avenue.
Posted: February 26th, 2011 2:36 AM
That intersection is high-trafficked by motorists, but public art such as this should be installed some place where pedestrians will see it.
OP Resident
Posted: February 24th, 2011 12:48 AM
$30,000 from the developer and how much from Oak Park taxpayers? Do we own the piece or just leasing it with an option to buy? Who pays for installation? The Oak Park Art Advisory Commission should be able to share the details. Glad that the work of an Oak Park artist was selected.
Kelly from Oak Park
Posted: February 23rd, 2011 10:48 PM
It's hard to debate such rigorously well-argued criticism as James', but I think an appropriate rejoinder would be: Cool! I agree that such a bold piece will be that much more striking against the subdued modernist box that is the Whiteco building.
tom broderick from oak park
Posted: February 23rd, 2011 12:51 PM
I've seen a couple of finished pieces of sculpture by this sculptor. One in Chicago along the lake front park. I think the other was at Navy Pier. Neither had the bold color of this one, but I enjoyed both. When the five finalists went online through the Wednesday Journal, it was hard for me to visualize them as large pieces. Now that this one has one, I look forward to the unveiling.
David Hammond from OakPark.com/Dining/Blogs
Posted: February 23rd, 2011 11:27 AM
There's a venerable tradition of local populations hating public sculpture in their area, at least in the intial phases. Picasso's loop sculpture is the classic example: first loathed, now loved. James, you're entitled to your opinion, of course, and thanks for offering it, but I'm guessing this work will grow on you and all of us. It certainly is a bolt of color in a colorless environment.
Posted: February 23rd, 2011 11:12 AM
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Me and my friends are stopping over at Stuttgart for a day in February.
We arrive on 17 Feb afternoon and leave on 18 Feb evening.
Do you have any suggestions on how to spend the day?
Tübingen or Neuschwanstein Palace? I would like to visit Black Forest. I know its too little time. Any suggestions on what I should choose?


text:
The perfect gift for someone celebrating a birthday, anniversary, or milestone event, this beautiful 14k yellow gold ring features a modified bypass band adorned with two genuine green sapphires and a natural diamond accent. The oval-cut sapphires have a combined 1.20 carat total weight and are ported from the underside to accentuate their moss-green color. The round cut diamond has .02 carat weight and anchors the bottom of the frame that swirls around the sapphires. A smoothly polished and contoured shank completes the ring.
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Felix Baumgartner, 43-year-old Austrian skydiver is attempting the unimaginable! Well, literally, he is trying to pull off a Rajinikanth. He will jump from 1,20,000 feet above the ground level. If the super jump results in a safe landing, he will become the first skydiver to break the sound barrier in the highest and fastest freefall in History.
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Comparison of bone marrow and adipose tissue-derived canine mesenchymal stem cells
Neurological, cardiovascular, gastrointestinal, urological and regenerative medicine
Bone marrow-derived mesenchymal stem cells (BM-MSCs) and adipose tissue-derived mesenchymal stem cells (AT-MSCs) are potential cellular sources of therapeutic stem cells. MSCs are a multipotent population of cells capable of differentiating into a number of mesodermal lineages. Treatment using MSCs appears to be a helpful approach for structural restoration in regenerative medicine. Correct identification of these cells is necessary, but there is inadequate information on the MSC profile of cell surface markers and mRNA expression in dogs. In this study, we performed molecular characterization of canine BM-MSCs and AT-MSCs using immunological and mRNA expression analysis.
Samples were confirmed to be multipotent based on their osteogenic and adipogenic differentiation. And these cells were checked as stem cell, hematopoietic and embryonic stem cell (ESC) markers by flow cytometry. BM- and AT-MSCs showed high expression of CD29 and CD44, moderate expression of CD90, and were negative for CD34, CD45, SSEA-3, SSEA-4, TRA-1-60, and TRA-1-81. SSEA-1 was expressed at very low levels in AT-MSCs. Quantitative real-time PCR (qRT-PCR) revealed expression of Oct3/4, Sox2, and Nanog in BM- and AT-MSCs. There was no significant difference in expression of Oct3/4 and Sox2 between BM-MSCs and AT-MSCs. However, Nanog expression was 2.5-fold higher in AT-MSCs than in BM-MSCs. Using immunocytochemical analysis, Oct3/4 and Sox2 proteins were observed in BM- and AT-MSCs.
Our results provide fundamental information to enable for more reproducible and reliable quality control in the identification of canine BM-MSCs and AT-MSCs by protein and mRNA expression analysis.
Mesenchymal stem cells (MSCs) have been successfully isolated from bone marrow
MSCs are defined by their plastic adherent growth and subsequent expansion under specific culture conditions and by their
The expression profile of cell surface markers and mRNAs is well characterized in other species. In many studies in humans and dogs CD29, CD44 and CD90 were regarded as positive cell-surface markers for MSCs
In veterinary medicine, the use of MSCs for tissue repair is helpful and is likely to increase in future. However, there have been few studies on cell surface markers and mRNA expression profiles of canine MSCs. Here we evaluated the canine BM- and AT-MSC cell surface markers CD29, CD44, CD90, CD34, CD45, SSEA-1, SSEA-3, SSEA-4, TRA-1-60, and TRA-1-81 by flow cytometry. We also analyzed the mRNA expression profile of Oct3/4, Sox2, and Nanog in canine BM- and AT-MSCs by quantitative real-time PCR (qRT-PCR). Finally, we used immunocytochemistry to examine the expression and localization of Oct3/4 and Sox2. The aim of this study was the biological characterization of canine MSCs isolated from bone marrow and adipose tissue.
Cell isolation and culture
Adherent cells were observed at the bottom of the culture flasks within 2 days; these cells were isolated from both bone marrow and adipose tissue after plating. Bone marrow-derived cells formed several colonies and proliferated, taking various shapes, including discoidal flat, triangular, and elongated (Figure
Figure 1
In vitro differentiation of BM-MSCs and AT-MSCs.
In vitro differentiation of BM-MSCs and AT-MSCs. Both types of cell were maintained in control medium (A, B). Osteogenic differentiation was identified by von Kossa staining (C, D) and adipogenic differentiation by Oil Red O staining (E, F). Scale bar, 200 μm.
In vitro differentiation
Osteogenic differentiation was demonstrated histochemically using von Kossa stain (Figure
Characterization of surface markers for MSC
Cell surface antigen phenotyping was performed on BM- and AT-MSCs by flow cytometry (Figure
Figure 2
Flow cytometry.
Flow cytometry. Comparison of cell surface proteins CD29, CD44, CD90, CD34, CD45, SSEA-1, SSEA-3, SSEA-4, TRA-1-60, and TRA-1-81 on primary cultures of BM-MSCs (A, C) and AT-MSCs (B, D). Solid histograms show nonspecific staining and open histograms show specific staining for the indicated marker. Three different donor MSC populations from each tissue type were analyzed and representative samples are shown.
Hematopoietic markers CD34 (BM-MSCs, 0.88 ± 0.21%; AT-MSCs, 0.25 ± 0.06%) and CD45 (BM-MSCs, 0.24 ± 0.07; AT-MSCs, 0.17 ± 0.02) were detected in BM-MSCs (Figure
BM-MSCs (Figure
mRNA expression analysis using quantitative real-time PCR
Expression levels of canine Oct3/4, Sox2, and Nanog mRNA in BM- and AT-MSCs were examined by qRT-PCR (Figure
Figure 3
Quantitative RT-PCR.
Quantitative RT-PCR. Expression levels of mRNAs for stem cell markers Oct3/4, Sox2, and Nanog in BM-MSCs and AT-MSCs. Each value was normalized to beta-actin expression. Statistical comparisons were made using Student's
Immunocytochemistry was used to analyze Oct3/4 and Sox2 proteins (Figure
Figure 4
Immunocytochemistry. Expression and localization of Oct3/4 and Sox2 in BM-MSCs and AT-MSCs. Immunofluorescent localization of Oct3/4 in BM-MSCs with DAPI counterstaining (C, D). Immunofluorescent localization of Sox2 in BM-MSCs with DAPI counterstaining (E, F). Immunofluorescent localization of Oct3/4 in AT-MSCs with DAPI counterstaining (I, J). Immunofluorescent localization of Oct3/4 in BM-MSCs with DAPI counterstaining (K, L). Scale bar, 40 μm.
In this study, we confirmed the potential of MSCs to differentiate into osteoblasts or adipocytes, and evaluated the protein and mRNA expression profiles of these cells. In addition, we compared the expression patterns of ESC markers and germ layer markers in MSCs derived from bone marrow and adipose tissue. BM-MSC and AT-MSC populations expressed CD29, CD44, and CD90 with similar intensity. In particular, in both BM- and AT-MSCs, more than 95% of the cell population expressed CD29 and CD44. Our results indicate that expression of CD90 was lower than that of other markers. However, many human studies have reported strong expression of CD90. This may be related to differences within species. Many human studies have reported positive expression of CD90 whereas many studies in mice have reported negative expression of CD90
The qRT-PCR analysis revealed expression of the stem cell markers Oct3/4, Sox2, and Nanog in canine BM- and AT-MSCs. In a human study, mRNAs of these markers were expressed in human MSCs
We performed immunostaining with Oct3/4 and Sox2 in MSCs. In both BM- and AT-MSCs, Oct3/4 was detected in the nuclear fraction, whereas Sox2 was detected in the cytoplasmic fraction. Several transcription factors are known to be localized in the cytoplasmic fraction, such as The Tead
Our study reveals the protein and mRNA expression profiles of canine BM- and AT-MSCs. The two types of cells showed similar cell surface marker profiles. Quantitative real-time PCR revealed expression of mRNAs for Oct3/4, Sox2, and Nanog in BM- and AT-MSCs. The localization of Oct3/4 and Sox2 was demonstrated immunocytochemically. mRNA expression of Nanog was greater in AT-MSCs than in BM-MSCs. Further studies are required to characterize canine MSCs with respect to the expression of other proteins and mRNAs.
MSC isolation and culture
Four young healthy female beagle dogs (1 year old, 9.5-11.3 kg body weight) were used. All animals were anesthetized with propofor (Hospira, Osaka, Japan) (7 mg/kg by intravenous injection) before tissue sample were taken. After incubation, anesthesia was maintained with isoflurane (1.5–2.0%) in oxygen. Animal experiments were carried out in accordance with the National Institutes of Health guidelines for the care and use of laboratory animals. The protocol of this study was approved by the University Committee for Animal Experimentation.
Under general anesthesia, bone marrow was aspirated from the proximal humerus using a general bone marrow biopsy technique. Briefly, a sterilized 13-gauge Jamshidi needle (Cardinal Health, McGaw Park, USA) was used to aspirate 5 ml of bone marrow into a syringe containing 5 ml of heparinized (1,000 units/ml) saline solution. Perioperative analgesic management was carried out by the pre- and post-operative administration of buprenorphine, which was administered twice daily for 3 consecutive days after surgery. In addition, ampicillin (25 mg/kg) was orally administered twice daily for up to 7 days after surgery.
The bone marrow collected was dissociated and then resuspended with a pipette. The suspension was centrifuged for 5 min at 300 ×
Adipose tissues were also harvested from each dog under general anesthesia. Subcutaneous fat pads (approximately 1.0 g) were harvested from the inguinal area. These pads were finely minced with scissors and then digested in 40 ml of PBS containing 0.15% collagenase (Invitrogen), with vigorous shaking for 60 min at 37°C. Samples were then filtered using 100 μm cell strainers (BD Biosciences, Franklin Lakes, USA) and washed with PBS. The cells obtained were seeded into T-75 cell culture flasks with 10 ml of control medium and incubated in the same manner as bone marrow cells.
In vitro differentiation
For osteogenic differentiation, passage 2 BM-MSCs and AT-MSCs were plated on 6-well culture plates at a density of 5.0 × 103 cells/cm2, and after incubation in control medium for 24 h, the medium was changed to osteogenic medium. The osteogenic medium was Canine Osteoblast Differentiation Medium purchased from Cell Applications (San Diego, USA). The medium was changed twice weekly. For osteogenic analysis, mineral deposits were quantitatively analyzed by von Kossa (Sigma, St. Louis, USA) staining at 14 days.
For adipogenic differentiation, passage 2 BM- and AT-MSCs were plated on 6-well culture plates at a density of 8.0 × 103 cells/cm2. The cells were cultured in control medium until confluency, and then the medium was changed to Canine Adipocyte Differentiation Medium (Cell Applications). The medium was changed twice in a week. Oil Red O (Sigma) staining was performed to analyze adipogenesis at 14 days.
Flow cytometry
Passage 2 BM-MSCs and AT-MSCs were placed in FACS tubes (BD Biosciences) at 2 × 105 cells/tube, washed with FACS buffer (PBS containing 1% sodium azide and 1% FBS, pH 7.2). The cells were incubated with antibodies including CD29-PE (BioLegend, San Diego, USA), CD34-PE (R&D Systems, Minneapolis, USA), CD44-FITC (eBioscience, San Diego, USA), CD90-PE (BD Biosciences), CD45 (Abcam, Cambridge, UK)
Reverse transcription and quantitative real-time PCR (qRT-PCR)
Total RNA was obtained from cultured BM-MSCs and AT-MSCs in passage 2. Total RNA was extracted using TRIzol reagent (Invitrogen) according to the manufacturer's protocol. Total RNA was measured by spectrophotometry. Total RNA (1 μg) was reverse-transcribed at 42°C for 15 min in 20 μl with QuantiTect (Qiagen, Düsseldorf, Germany) after inactivation of reverse transcription by heating at 95°C for 3 min.
The cDNA product was subjected to real-time PCR according to the user instructions for the Real-Time PCR System 7300 (Applied Biosystems, Foster City, CA). qRT-PCR was performed at 95°C for 5 s and 60°C for 34 s in 20 μl buffer containing SYBR premix ExTaq II and ROX Reference Dye (Takara Bio, Shiga, Japan) and 0.2 μM each of the primers (Table
Immunofluorescent staining was used to assess expression of the transcription factors Oct4, Sox2, and Nanog in BM- and AT-MSCs. Passage 2 cells were cultured in 4-well chamber slides (Nunc, Roskilde, Denmark) until 50% confluency. The cells were washed twice with PBS and fixed with 4% paraformaldehyde at room temperature for 30 min. After washing thrice with PBS, the cells were incubated with blocking solution containing 0.4% Triton X-100 and 4% Block Ace (DS Pharma Biomedical, Osaka, Japan) in PBS at room temperature for 1 h. The cells were incubated with rabbit polyclonal primary antibodies against Oct3/4 (Santa Cruz Biotechnology, Santa Cruz, USA), Sox2 (Stem Cell Technologies, Vancouver, Canada), and Nanog (Peprotech, Rocky Hill, USA)
Additional file 1
Table S1. Antibody Informations.
Click here for file
Statistical analysis
Data were analyzed with an independent samples
BM-MSC, Bone marrow-derived mesenchymal stem cell; AT-MSC, Adipose tissue-derived mesenchymal stem cell; ESC, Embryonic stem cell; qRT-PCR, Quantitative real-time polymerase chain reaction; SSEA, Stage specific embryonic antigen; TRA, Keratin surface-associated antigen tumor-related antigen.
Competing interests
None of the authors has any financial or personal relationships that could inappropriately influence or bias the content of the paper.
Authors' contributions
HT and DZ designed the study, drafted the manuscript, and analyzed data; IY helped with editing and revision of the manuscript; YH helped with collection of samples and revision of the manuscript; MM helped with FACS analysis and revision of the manuscript; and TA contributed to the study design and helped with editing and revision of the manuscript. All authors read and approved the final manuscript.
This work was supported in part by the Supported Program for the Strategic Research Foundation at Program for Private Universities from the Ministry of Education, Culture, Sports, Science and Technology of Japan (MEXT), 2008–2012, and a Grant-in-Aid for Science Research (No. 21380195 to T. Arai.) from MEXT. The authors would like to thank Enago (
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Differentiation potential of conditionally immortalized mesenchymal progenitor cells from adult marrow of a H-2Kb-tsA58 transgenic mouse
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Highly purified CD34-positive cells reconstitute hematopoiesis
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Validation of human periodontal ligament-derived cells as a reliable source for cytotherapeutic use
Functional characterization of calcium-signaling pathways of human skin derived mesenchymal stem cells
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Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement
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Cell surface and transcriptional characterization of human adipose-derived adherent stromal (hADAS) cells
Comparative characteristics of mesenchymal stem cells from human bone marrow, adipose tissue, and umbilical cord blood
Immunophenotype of human adipose-derived cells: temporal changes in stromal-associated and stem cell-associated markers
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Modulation of the activity of multiple transcriptional activation domains by the DNA binding domains mediates the synergistic action of Sox2 and Oct-3 on the fibroblast growth factor-4 enhancer
Growing bone and cartilage: The role of mesenchymal stem cells
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Cytokine signals modulated via lipid rafts mimic niche signals and induce hibernation in hematopoietic stem cells
Monoclonal antibodies that define canine homologues of human CD antigens: summary of the First International Canine Leukocyte Antigen Workshop (CLAW)


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The Ultimate Fabric Sourcing Checklist for Fashion Designers
We share a list of steps to take and pitfalls to avoid for a smooth fabric sourcing process!
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Tips on how to effectively navigate production of your fashion collection overseas.
Business changes fast and fashion changes even faster. Make sure that you spend time every month on fashion business education.
There are several tech tools out there that focus specifically on certain needs that you have for your fashion business. We've rounded up six for you.


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After having our whole 2 week trip planned to NL for last summer and having to cancel because of DH surgery, I'm starting again. This time, 6 adult friends are joining us because they heard how wonderful NL is.
We had originally planned to go across the province, but now I'm starting to rethink it.
Please tell me your thoughts.
St John's late night arrival 3 nights
260 miles to Twillingate 3 nights
250 miles to Rocky Harbour 4 nights
380 miles to Bonavista 3 nights
180 miles to Witless Bay 2 nights
20 miles to St John's 1 night
It seems like a lot of driving. We like to walk/hike and poke around areas (not shop!) Gros Mourne sounds so wonderful, but is it really pushing it?
Am I right in thinking driving on Rt 1 may average 50 MPH? Of course, we'd probably make stops along the way, but I'm figuring driving time. So thinking 5, 5 ,8,3 hours between towns.
I know folks may say we have to come back and hopefully we will....
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After having our whole 2 week trip planned to NL for last summer and having to cancel because of DH surgery, I'm starting again. This time, 6 adult friends are joining us because they heard how wonderful NL is.
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I would think this sounds reasonable, unless you really hate highway driving. The Rocky Harbour-Bonavista day is the only looong drive.
You can easily do 55-60 on the TCH (Rte 1), as it goes through very few communities. The speed limit is 100 km almost everywhere on the TCH. Once you leave it (to branch off for Bonavista or Twillingate) your speed will drop drastically. However, a chance to drive through the tiny villages, and along the seacoast, is one of the main reasons to come here.
These are all great places for walking/hiking, and I assume you'll arrange a boat tour in the Witless Bay area. The summer theatre in Trinity (near Bonavista) is worth a look.
And, for the love of heaven (and your pocketbook), don't come here to shop!! Those of us who live here--and love it -- still LEAVE here to shop.
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Hi Clousie,
Wow! It's a lot of driving but certainly possible. And there'll be lots to see and do, including beautiful walks, in all the areas you've chosen. I particularly like the Skerwink Trail near Trinity as well as a (moderate) section of the East Coast Trail near Witless Bay. I'd also second nfldbeothuck's suggestion for the summer theatre in Trinity ... fabulous!. You may also want to consider staying in Trinity ... lots of nice B& B's and it's a gorgeous community. The boat trip in Witless Bay is also great.
The only thing I might change is the amount of time you've chosen to stay in Twillingate. I think 2 nights is enough especially given that you want to include Gros Morne. The driving times you've estimated are reasonable.
I love Gros Morne, Lanse aux Meadows and other places along the Northern Peninsula. It's beautiful ... different from the rest of the island. However I think this area deserves a separate trip. Perhaps you might want to consider the west coast for a return visit. There'll be so many things you'll enjoy doing in the other areas and you won't feel rushed.
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Thanks for the comments/suggestions. As you both mentioned, we really do hope to spend time in small villages, soaking in the scenery and doing lots of walks along the coast. We like to savor our time, take time to relax, but still see the main sights.
While staying in Twillingate area, I thought of going over to Fogo Island for a day to walk and enjoy scenery. Any thoughts on this idea?
Before I wrote this reply there were 3 replies listed. Did a third person post and it not show up? Maybe it's just a "Fodor's thing."
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Hi Clousie,
Yes I've noticed the discrepancy in posting numbers too on occasion ... not sure why.
I think Fogo Island will be a lovely day trip. It's been receiving a lot of attention lately with BIG plans to promote and revitalize its culture and traditions. It'll probably take a couple of hours to drive and get onto the island from Twillingate and as there are 11 small communities it'll take all of your day to explore. Be sure you know the ferry schedule particularly when the last one leaves to return to Farewell!
Another beautiful community is Change Islands which attracts a lot of artists 'from away'. This may be easier to explore than Fogo Island and just as lovely. You take the ferry from Farewell to access Change Islands too. However that's another day trip!
About 20 minutes prior to arriving in Twillingate you'll see route 345 on your left. This leads to a gorgeous area, more than worth a visit if you enjoy unspoiled scenery along the ocean. The tiny historic communities of Moreton's Harbour and Tizzards Harbour are about a 20 minute drive along route 345. Moreton's Harbour also has a small museum. Visit Taylor's Room to your left as you enter and see lovely ocean views from the hill. Tizzard's Harbour, a liitle further along, is an undiscovered gem and particularly pretty. You can easily spend a relaxing morning here in these two communities while based in Twillingate ... perhaps taking along a picnic lunch and enjoying lovely walks.
Lots of choices ... Hope this helps.
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In the last 90 days, 0 listings have been listed, which means office spaces most likley are leasing quickly. You'll want to be prepared to make an offer immediately. About Inf% of the office spaces in the Wooten are subleases, so you might be able to snag a great spot on a short term. There aren't many listings below 2,000 square feet posted, so finding a space for a small business might be tough.
The standard measurement for office space in this area is around sqft. Most properties in this area are approximately 2 stories.
Not much of the real estate is used for commercial space, so it might be hard to find office space. Information is the dominant industry in this market. Commute by walking is the most popular way to get to work amongst Wooten residents. Commuting approximately an hour a day is the norm for those who opt to reside in this part of town.
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