text:
|Publication number
|Publication type
|Application number
|Publication date
|24 Jul 2007
|Filing date
|22 Dec 2005
|Priority date
|22 Dec 2005
|Fee status
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|Publication number
|Peter Kiesel, Oliver Wolst, Michael Kneissl, Huangpin Ben Hsieh, Oliver Schmidt
|Original Assignee
|Palo Alto Research Center Incorporated
|Export Citation
|BiBTeX, EndNote, RefMan
|Patent Citations (6), Non-Patent Citations (5), Referenced by (53), Classifications (27), Legal Events (3)
|External Links: USPTO, USPTO Assignment, Espacenet
U.S. application Ser. No. 10/976,434, filed Oct. 29, 2004, entitled "Anti-Resonant Waveguide Sensors", is a related application, the entire specification of which is incorporated herein by reference.
In the last several years many different approaches for automated detection of biological materials have been proposed and developed. These commonly are biosensors and biochip readers which often use live organisms or biological molecules, such as antibodies, nucleic acids (e.g., DNA chips), or enzymes as biological recognition elements to specifically bind target analytes. The specific binding of the target can be monitored by a recognition signal.
One of the most sensitive detection techniques available today is based on fluorescence excitation of dye-labeled targets. Current detection devices mostly fall into one of two categories, the first employs a white light source (usually a high power arc lamp) with CCD detector, and the second using laser excitation with photomultiplier tube (PMT) light collection in combination with a scanning technique. To meet the detection demands, a fluorescent scanner usually has a sensitivity of detecting at least 2-5 fluorphores per μm2; a resolution of 10 μm (pixel size) or better; and has a dynamic range of 5 orders of magnitude. Moreover, it needs to perform scanning of one slide in reasonable amount of time, typically five minutes or less per fluorescence channel. Problems with systems employing a white light source include the need of expensive filters and the short lifetime of arc lamp, which can be costly; while the approach using lasers is not practical for multicolor exaction due to the high cost of multiple lasers. Both types of scanners are costly and large enough to take up a substantial portion of a workbench.
A common disadvantage of all fluorescence based reading is the relatively inefficient use of the excitation light, due to the limited interaction with the fluorescence molecules. This increases the demand on the excitation source as well as on the detection system because unused excitation light is transmitted, scattered or absorbed elsewhere, decreasing the operational efficiency of the system and increasing background noise.
In order to improve the interaction, fluorescence readers employing optical waveguides have been proposed. A general disadvantage of conventional waveguide approaches is that the substance itself (e.g., liquid, which contains the molecules of interest) are not used as an optical waveguide, since the refractive index is lower than the index of the surrounding material (e.g., glass polymer, PDMS). Therefore, conventional optical waveguides typically provide only a weak interaction via evanescent waves with the target molecules, which are specifically bound to the waveguide surface. Existing waveguides also do not efficiently maintain light in the waveguide due to enhanced light scattering if the layer bound to the surface is inhomogeneous.
Thus, due to the required sensitivity of detection, and the inefficiency in the fluorescence excitation of existing systems, high powered light sources are necessary in order to obtain a sufficient amount of emitted fluorescing light. Such high powered light sources take up large amounts of physical space, require large amounts of energy to operate, and have a comparatively short life span requiring removal, replacement, and oftentimes realignment of lamp.
It is to be understood that fluorescent microscopes, as well as other detectors which employ fluorescence concepts, have the same issues regarding effective illumination and light collection from a sample and therefore face the same challenges as discussed above.
A sample detection system employing an anti-resonant waveguide, having a sample with a first index of refraction, and a top layer and substrate surrounding the sample, where the top layer has a second index of refraction, and the substrate has a third index of refraction. The second index of refraction, and the third index of refraction are both greater than the first index of refraction. A detection device of the system includes a low power light source used to direct light into the sample and generate an anti-resonant optical mode in the sample, and an analyzing system to detect the interaction of the light propagating in the sample.
Improved compact sensors that enhance interaction between light and target analytes in a sample are described. Light from a comparatively low power light source, such as but not limited to a Light Emitting Diode (LED), Laser Diode (LD) or Superluminescent Light Emitting Diode (SLED), is coupled into a sample. It is to be appreciated that while the foregoing mentions light sources as being one of LEDs, LDs or SLEDs, a conventional higher power light source can also be used in connection with anti-resonant waveguide coupling. However, since the anti-resonant waveguide approach enhances the light target interaction anti-resonant waveguide coupling also works with the mentioned low power light sources such as LEDs, LDs and SLEDs.
By controlling the angle of light entry into the sample, anti-resonant waveguide modes are generated. The anti-resonant modes allow the sample itself to serve as an optical waveguide resulting in increased interaction between the target molecules and the light. A light retention component acts to maintain the light within the waveguide to further improve the efficiency of the system
Light beam 112 enters sample 116 at an angle of incidence 120. As used herein, reference to the word "light", "light beam" and "optical" is should be broadly interpreted to include a broad range of frequencies including ultraviolet, visible, infrared, and far infrared radiation as well as terahertz radiation. As used herein, the angle of incidence is the angle with respect to a normal 124 of the surface 128. The angle of incidence is carefully selected such that an anti-resonant guided optical wave (ARGOW) or mode of light can be set up within sample 116.
Sample 116 is typically a thin film of liquid carrying the target analyte (e.g., biological molecules) to be analyzed. Sample 116 may also be a gas or an aerosol carrying the analyte to be analyzed. If the sample is a gas or aerosol, sealing materials around the perimeter of the chamber containing the sample keeps the gas between substrate 132 and covering layer 136. Sample 116 thickness is usually kept larger than the wavelength of light being used to analyze the sample.
Substrate 132 and covering layer 136 border sample 116 sides. Substrate 132 and covering layer 136 are typically made from a transparent material such as glass. In one embodiment, glass slides are used for substrate 132 and covering layer 136. The index of refraction of the substrate and covering layer are slightly higher than that of the sample 116 to facilitate generation of an anti-resonant wave in sample 116. An example index of refraction of substrate 132 and covering layer 136 might be between 1.4 and 1.8 while the index of refraction of a liquid sample 116 might be between 1.2 and 1.4 although as will be explained, a wide range of other indices are also possible.
The actual conditions used to create an anti-resonant guided optical wave (ARGOW) propagating through a sample sandwiched between two higher index materials may be found by computing the Eigensolutions of the Helmholtz equation for a plane wave propagating along a slab waveguide structure. A general Helmholtz equation for the electric field E is given by:
(∇ 2 +|{right arrow over (k)}| 2)E=0; |{right arrow over (k)}|=|{right arrow over (k)} 0 �n (Eq.1)
Assuming a plane wave that propagates along a x-direction within a slab waveguide structure, and confining the wave with respect to the z-orientation results in the following solution to the Helmholtz equation:
where E denotes the electric field, {tilde over (E)}(z) its z-dependence, kx the x-component of the wavevector. {right arrow over (k)}0 is the lights vacuum wavevector and n the materials refractive index.
In this case the Helmholtz equation reduces to:
The Eigensolutions {tilde over (E)}(z) can be characterized by kx, or for convenience by a so called effective refractive index neff defined as:
In the previously described slab index guided waveguide structure, the equations above can be numerically solved resulting in a large number of Eigensolutions {tilde over (E)}(z). These Eigensolutions are called-optical modes. Equations 3 and equation 4 also enable computation of the respective refractive indices neff and modal confinement factors Γ of these modes.
A confinement factor Γ corresponds to the fraction of the light intensity confined in the waveguide core. For maximum interaction between target molecules in the sample and the light beam, the sample or analyte itself serves as the waveguide core. The core is surrounded by a cladding layer, typically the portion of the medium immediately adjacent to the sample. In future references to the cladding, the "cladding layer" shall refer to a portion of the medium that lies immediately on either side of the sample. The thickness of the cladding layer can be chosen within a wide range but the typical thickness is a several wavelengths of the light propagating in the medium.
In the case of "anti-resonant" waveguides, herein defined to be a waveguide in which the core has a lower refractive index than the cladding layer, a number of optical modes with reasonably large confinement factors, up to and past 90%, can be found. These modes (or Eigensolutions) are characterized by effective refractive indices neff close to (typically slightly smaller than) the refractive index n of the core layer material. When the core thickness is large compared with the wavelength of propagating light, the neff of these modes of interest, approaches the refractive index of the core n.
Each Eigenmode can be excited by directing a beam of light at the waveguide at a specific angle of incidence. The angle of incidence corresponds to the effective refractive index neff.
When analyte 204 thickness 220 (typically waveguide core diameter dcore≈10 . . . 100 μm) is large compared with the wavelength of the incident light (λ=0.3 . . . 2 μm) the approximation of (Eq.5) is acceptable. Using the equation 4 approximation allows substitution of analyte refractive index n for effective refractive index neff. The substitution results in an angle of incident that depends only on the refractive indices of the analyte, the core layer and the outside world:
An example of a typical set of refractive indices might be an analyte of water with an n=1.34, a glass cladding layer with an n′=1.5 and an air or vacuum surrounding with n″=1. Using a glass cladding in an air surrounding for an example, the table in
Although two geometries and end facette designs have been provided in
In order to generate the graph of
In the measurements, the measured fluorescence intensity per unit area was similar to that which has been obtained by perpendicularly (from the top) focusing the total excitation power from the LED onto a small spot (e.g. 3�3 mm2) in the sample. The improved fluoresce results from a more efficient use of the excitation light by coupling the light into an ARGOW, in particular, guiding the light between the glass slides. This compares favorably to regular fluorescence detection when the excitation light is input perpendicular to the sample plane and results in transmission of most of the light. Using anti-resonant waveguide excitation the sample itself guides the excitation light between the glass slides providing a long interaction length between light and fluorescent molecules.
Each mode can be specifically excited by adjusting the incidence angle φ (the angle 120 of
Changes in light wavelength also produces slight changes in optimum incidence angle. For example, substituting infrared light (˜1500 nm) for blue light (˜480 nm) only changes the optimum incidence angle by about 1.8�. The difference in the dispersion of glass and water has a larger influence compared to the different confinement conditions for the different wavelengths which have only small impact on incidence angle.
The ability of the overall system to accommodate changes in light frequency and sample thickness makes it ideal for use in parallel analytic techniques. These are particularly useful in sophisticated systems where several different tests are to be conducted in parallel to determine the composition or presence of various target analytes.
In the preceding discussion, analysis has been done on step index profiles such as that shown in
Returning to
Wavelength sensitive elements enable identification of signatures and specific biological or chemical agents. Detectors 140, 144 may also integrate the wavelength sensitive elements with conventional optics or micro-optics components including mirrors and lenses. In some embodiments, the detectors may include a means for converting the optical signal to an electrical signal. Such conversions may be achieved using a charge coupled device, a photosensor, or any of a variety of conversion devices. Once converted to an electrical signal, detector 140, 144 output can be analyzed using electric processors, such as microprocessors (not shown).
Detector 140 of
In an alternate embodiment, instead of detecting light that is transmitted, a second detection system such as detector array 144 may detect light that is scattered or otherwise output by sample 116. Scattered light may be caused by reflection or refraction of light by molecules in sample 116. Example scattering techniques include elastic and inelastic light scattering spectroscopy as described in Introduction to Biophotonics, by Paras N. Prasad ISBN 0471-28770-9, Wiley-Interscience 2003) which is hereby incorporated by reference in its entirety.
In still another embodiment, light output from sample 116 may be caused by fluorescence that results from binding of chemical elements in the sample to biological materials. The binding results in fluorescence when an excitation source, such as the anti-resonant light propagating in the sample is present. U.S. Pat. No. 6,577,780 by Lockhart entitled Cell Designs for Optical Sensors describes using antigens that attach to antibodies resulting in a structure that fluoresces in the presence of an evanescent field. U.S. Pat. No. 6,577,780 by Lockhart is hereby incorporated by reference in its entirety. By using anti-resonant waves propagating through the sample instead of evanescent fields, the sensitivity of the system can be improved.
Besides the examples given, many other optical detection and sensing techniques may be used with sensors 140 and 144. Those techniques include, but are not limited to single or multicolor light-induced intrinsic fluorescence or fluorescence from tagged molecules and applications derived from the manipulation of the fluorescent lights such as fluorescence lifetime imaging microscopy (FLIM), fluorescence resonance energy transfer (FRET), fluorescence correlation spectroscopy (FCS), etc., light scattering or vibrational spectroscopy (Raman, IR) or spectroscopic applications utilizing optical activity of chiral media such as circular dichroism (CD), among others. A more detailed description of various detection techniques utilizing photon interactions is provided in Chapter 4 of "Introduction to Biophotonics" by Paras N. Prasad, ISBN 0471-28770-9, Wiley-Interscience 2003), which is hereby incorporated by reference.
With continuing attention to
As illustrated in
Turning attention to
As described in the foregoing, the use of the anti-resonant waveguide permits for the excitation light to be guided between the glass slides, and therefore provide increased interaction between the excitation light and the fluorescent molecules. Therefore, the anti-resonant waveguide concept more efficiently uses the light from the light source. However, an area where light is most likely to escape from the waveguide is at the surrounding end facets 1052, which as shown in
Turning to
In an alternative embodiment,
In still a further embodiment,
For example,
The concepts discussed in connection with
It is also to be understood, excitation light beams (e.g., 112, 112′) have been shown to be either directly provided or provided through optics to the anti-resonant waveguide. Therefore, the light beams can be coupled into the anti-resonant modes using free-space optics or by conventional waveguides such as glass fiber, glass bundles or planar optical waveguides as examples. The previous drawings are intended to represent such known coupling techniques. Further, while light beams (112, 112′) are depicted in the foregoing discussion as being entered at an end of the waveguide, in still a further embodiment, it is considered that the light beams (112, 112′) are positioned to enter the waveguide through a side of the waveguide. In this embodiment, multiple or less coherent light sources may be used to provide a wider width of coverage. Further, containment components in this embodiment would be designed to permit the light beam (112, 112′) to enter through the side facet.
A particular aspect of the present application is that through increasing the maintenance of light within the anti-resonant waveguide, and thereby improving excitation light efficiency, it is possible to improve the overall fluorescence efficiency. A beneficial feature of the improved efficiency of fluorescence is the ability to implement fluorescent based readers in a more compact, low cost configuration. More particularly, and as previously mentioned, in existing systems the common light source used in, for example, a conventional white light system (i.e., one which employs white light sources) may be various ones of the xenon, halogen or deuterium lamps having characteristics such as:
Table 1 summarizes light power of the above lamps, where the light power is focused onto a 15�20 mm2 area for the different light sources (estimated for a spectral width of 10 nm).
10 mW
4 mW
0.2-1 mW
4-50 mW
In existing systems, these high-powered, physically large lamps are necessary in order to generate sufficient emissions within absorption range of existing fluorescent dyes, such as those shown in Table 2.
Alexa Flour 350
346 nm
442 nm
Alexa Flour 546
556 nm
572 nm
Alexa Flour 594
590 nm
617 nm
Alexa Flour 660
668 nm
698 nm
381 nm
445 nm
Bodipy FL ATP
505 nm
515 nm
Bodipy TMR
542 nm
574 nm
489 nm
506 nm
550 nm
565 nm
650 nm
690 nm
359 nm
461 nm
494 nm
518 nm
Lucifer Yellow
435 nm
532 nm
576 nm
601 nm
Texas Red
595 nm
620 nm
By use of the anti-resonant waveguide concepts of the present application, it is possible to use less powerful, much smaller and less expensive light sources such as LEDs, LDs and SLEDs. Benefits and operational characteristics of these devices are discussed below. It is of course to be understood that a conventional light source can be used in combination with the anti-resonant waveguide concepts described herein.
High power UV, visible, and IR LEDs are commercially available. For example, the Luxeon V Star power LEDs are offered in the wavelength range between 430 nm to 550 nm, covering the blue and green portions of the light spectrum. The spectral width (FWHM) ranges between 20 nm (@ 430 nm) and 35 nm (@ 550 nm). These LEDs are specified to run at 700 mA dc with operating voltages below 7V. DC output power under these operating conditions are between 500 mW for royal blue (440 nm-460 nm) and about 100 mW for green (520 nm-550 nm). High efficiency yellow, orange and red LEDs in the wavelength range between 590 nm and 650 nm are also commercially available. External quantum efficiencies in that wavelength region range between 20% (590 nm) to 55% (@ 650 nm). Incorporated in a high power heat sink package, these efficiencies correspond to output powers between 100 mW (@590 nm) and 260 mW (@650 nm) for a DC drive current of 250 mA. Higher output powers are possible with higher drive currents and improved heat-sinking.
LEDs from other sources at shorter wavelengths have also been demonstrated. External quantum efficiencies of 30-40% have been reported for InGaN LEDs emitting between 380 nm and 410 nm. Packing those LEDs into high power LED packages, result in output powers in the range between 600 mW and 800 mW (at drive currents of 700 mA). Progress has been reported on a 365 nm UV LEDs with output powers of 100 mW. Researchers at Palo Alto Research Center (PARC) of Palo Alto, Calif. and LumiLeds Lighting of The Netherlands, have reported a 30 mW UV LED emitting around 370 nm. Table 3 summarizes output power levels for single chip LEDs at different emission wavelengths for the above discussed devices.
370 nm
400 nm
450 nm
530 nm
590 nm
650 nm
30 mW
700 mW
500 mW
100 mW
>100 mW
>260 mW
Another light source which may be used in accordance with the present concepts are superluminescent light emitting diodes (SLEDs) which have been shown to be optimum light sources in optical coherence tomographs (OCTs), fiber sensor and optical coherence domain reflectometer (OCDR) applications because of their wide bandwidth and high output power. Currently, SLED devices based on GaAs/or InP material system are commercially available at 820 nm, 1300 nm and 1550 nm windows from different vendors (e.g. InPhenix Corporation of Livermore, Calif. and Exalos AG of Zurich, Switzerland).
SLED is an edge-emitting semiconductor light source. The unique property of an SLED is its high output power and high power density, similar to an injection laser diode (LD), but with a broad emission spectrum and low coherence, similar to a light emitting diode (LED). SLEDs are based on stimulated emission and similar in geometry to lasers but have no built-in optical feedback mechanism required by LDs for stimulated emission to achieve lasing. A main difference for SLED operations compared to LEDs is SLEDs have a higher gain and higher current density. A main difference for SLED operations compared to LDs is SLEDs have a stronger non-uniformity of photons and carrier density distribution inside the active region. SLEDs have structural features that suppress the lasing action by reducing the reflectivity of the facets. SLEDs may be considered essentially highly optimized LEDs. While SLEDs operate like LEDs at low current levels, their output power increases superlinearly at high currents. There are six key parameters used to characterize SLEDs: (i) Output Power, (ii) Optical Gain, (iii) ASE Spectrum Bandwidth or 3 dB Bandwidth, (iv) Spectrum Modulation or Ripple, (v) Coherence Length, (vi) Coherence Function. Every SLED has two counter-propagating beams of amplified spontaneous emission traveling along the active region. A perfect SLED would be an optimized traveling wave laser diode amplifier with zero reflection from the active channel ends. However, a perfect SLED is virtually impossible to realize due to the physical limitations of some of the manufacturing processes such as antireflection coatings (AR).
Thus, in place of the light sources used in existing systems, through implementation of the present concepts it is possible now to manufacture fluorescence devices employing much smaller, compact and efficient lighting sources (e.g., LEDs, LDs and/or SLEDs), than now possible in existing fluorescence detection devices. Thus, systems employing LEDs, LDs and SLEDs offer a number of advantages compared to conventional light sources including:
In consideration of the above, shown in
By use of system 1080, which can employ multiple LEDs LDs, SLEDs, multicolor excitation can easily be performed in a time sequential approach, or by parallel coupling of light sources. By using the LEDs LDs, SLEDs for excitation, the sequential approach can be done very easily since the light sources can be switched on and off quickly, in contrast to a conventionally used light source which usually needs long warm up times. For applications where very strong excitation is required, more light sources (e.g., LEDs, LDs, SLEDs) of the same type may be coupled in simultaneously. Again, since the excitation light is efficiently used and guided within the sample, a less demanding and therefore less expensive or even no detection filter may be required. This design, thus enables a simpler, more compact and less expensive system design both for single excitation and in the case of multicolor excitation.
The described excitation concepts implementing anti-resonant waveguide modes and smaller more compact light sources are particularly also useful in combination with microfluidic devices. For example, as shown in
The optical waveguide can be inline or perpendicular to the channels since thin walls between different channels will not result in disruption of the multiple optical waveguide configurations. By this design, multicolor excitation can be applied in a time sequential manner or by parallel launching of different light sources as illustrated, for example, in
Illustrating a particular implementation of the above concepts, attention is directed to
Using the concepts of the present application, biochip reader 1140 of
As can be seen between
With attention to another particular implementation,
Although optical detection techniques have been described, other methods of detecting the enhanced light-target interaction may be used. For example thermal detection techniques may be used. Predetermined light wavelengths may initiate a specific exothermic or endothermic chemical reaction which causes a temperature change. The detected temperature change indicates the presence of the reaction and thus the presence of compounds needed to create the reaction. Other example detection techniques include, but are not limited to, ARGOW induced photo ionization or photo fractionation. The photo ionization or photo fractionation generates charged particle which can be detected by known means such as a Coulter Counter.
In order to speed up analysis of the samples, parallel processing of a sample may occur. Thus the techniques described are not mutually exclusive and may be used in conjunction or in parallel to yield rapid detailed analysis of molecules in the sample.
The foregoing has been provided as examples to facilitate understanding of the invention, and to provide sample calculations. Further, while the foregoing examples have described the emitted light from the sample as fluorescing light, the output may be phosphorescence light or other output responsive to the cited excitation sources, or to other excitation sources, including but not limited to x-ray radiation or electron beam irradiation. However, the scope of the application should not be limited to these geometries or examples, nor the particular analysis techniques described. Instead, the concepts should only be limited by the claims, as originally presented and as they may be amended to encompass variations, alternatives, modifications, improvements, equivalents, and substantial equivalents of the embodiments and teachings disclosed herein, including those that are presently unforeseen or unappreciated, and that, for example, may arise from applicants/patentees and others.
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|U.S. Classification
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|International Classification
|Cooperative Classification
|European Classification
|22 Dec 2005
Owner name: PALO ALTO RESEARCH CENTER INCORPORATED, CALIFORNIA
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text:
February Conference
by Mira R.
On SRI I got a 977 and I need a 740 to be a proficient student by the end of the year.
One thing I need to work on is things like Let It Snow (reading the text, then answering questions) because I got a 7/11.On my voca review I got a 11/12. On my Dust of Snow packet I got a 9/10.I feel like in reading I am a higher than the average student.
One thing I did well on is my Settlers & Indians because I got a 6/6 on that.
One thing I could work on is my News ELA because I got a 3 on that (that was my lowest grade in writing! :D )
I got a 4 on my Colo. Persuasive Essay, a 4 on my Settlers & Indians, and a 3 on my News ELA. I think I am doing well and above grade level.
One or two things I did well on was my Add and subtract fractions, and Multiply and divide with 0 and elapsed time.
One thing I could work on is reducing fractions into the simplest form. I got a 8/10. (Again my lowest score :D )
With everything else I got 1 thing wrong, on Long Division I got 9/10.
I got 3/4 on Fractions greater, less, or equal to 1/2
And on Unknown numbers in an equation I got 4/5.
In math I think I'm doing well. I think I'm a little over grade level.
Social Studies and Science
On my Chapter 4 Unit test I got 15/18.
One thing I am learning in science is about fossils.
For my score on the Chapter 8 Unit test I got 27/30.
I think I am doing very well with my behavior. I have been helping my classmates (especially Chase! :D ) with their work. I love to help out around the classroom and I always try to finish my work. Sometimes I don't know what to do and get confused, but usually I either figure it out or ask Mrs. Morgan. I listen and try my best in everything I do.

subset: commoncrawl


text:
I have 8924 xper and i would like to give it to someone if possible because im closing my gag account, if this is not possible im going to donate all to RAVEN because i can't get an Amazon gift card as i dont live in America
Most Helpful Girl
you are the only one to know what to do with your xper
have a look at our FAQ page
but if you really wanna give it to someone.. its fine00|00|0
Possible to give to someone?
- Show AllShow Less
I'll mis u
lol have a nice life anon
Most Helpful Guy
wrong. u can get an amazon gift card no matter where u live... it's not for america only.
by the way, y u wanna leave? please think about it once more...00|00|0
Because everything is repeated its like im in pre school nothing changes
- Show AllShow Less
lol 4chan... hell no


text:
About the Book
As a small child we are always looking up searching for answers with arms held up towards Heaven looking for comfort, love, guidance. Steeples represent upward progress, knowledge, guidance, and inspiration. Steeples point to the sky to guide us to somewhere we can go to for answers. Steeples such as those on churches, mosques or synagogues guide us to places where we can seek divine guidance from our creator. No matter where you are you can always see steeples in the sky reaching toward Heaven and showing us a place to go for peace.
Features & Details
- Category Arts & Photography
Standard Portrait, 8×10 in, 20×25 cm
36 Pages
- Publish Date Nov 16, 2013
- Language English
- Tags Historic sites, Temple, Steeple
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text:
Don't-Miss Mobile World Congress Stories
Future electric cars could refill batteries from roads infused with wireless charging
Charging an electric car while driving may sound like a wild idea, but Qualcomm wants to bring that capability to automobiles.
A head-to-head look at the LG G5 and Samsung Galaxy S7
Having spent some time with these hot new Android phones, we've already formed a few preliminary opinions on how they stack up.
Don't expect another LG Nexus phone this year
An LG spokesperson says the company wants to focus on its own brand instead of building another Google phone.
Oral B's high-tech toothbrush has Bluetooth, gyroscopes, accelerometers, and cloud storage
Oral B's next toothbrushing system will have accelerometers, gyroscopes, a Bluetooth link to a smartphone app, and cloud storage. Have they left anything out?
Report: Sony's Xperia Z range of smartphones is no more
The company confirmed the Z line will be no more, turning their focus to the Xperia X series.
Take a quick stroll with us through Google's Android garden
Each year, Google sets up a shrubbery-laden outdoor funhouse for Android lovers. It's too much fun.
Google's Android garden at MWC is a can't-miss for Android fans
Google didn't make any big Android announcements at MWC, but they did have some fun demos and delicious hot chocolate.
Project Tango can be your virtual museum tour guide, and much more
We toured a museum with a Project Tango tablet as our augmented reality guide.
Google's Project Tango museum tour
Google demonstrates how Project Tango's precise indoor location can change your museum-going experience forever.
Oppo shows off faster-than-fast charging for its future smartphones
The most frustrating thing about Oppo's SuperVOOC fast-charging demonstration at Mobile World Congress is waiting for the battery to discharge so that they can run it again.
Nextbit's CEO and design chief talk about the Robin's style, camera, and what's next
We caught up with Nextbit's CEO and Chief Product and Design Officer about Robin's design, why it eliminated the app drawer, and what's next in the pipeline.
Xiaomi's U.S. debut is 'on the radar,' says Hugo Barra
China's top smartphone maker is thinking about launching its phones in the U.S., the head of its international business said Wednesday.
Xiaomi unveils low-cost, high-powered Mi 5 smartphone
The first new flagship smartphone in over a year from China's Xiaomi packs technology to match the iPhone 6 and Samsung Galaxy S7, but at around half the price.
LG's G5 vs. Samsung's Galaxy S7: A tale of two press conferences
LG and Samsung announced their flagship phones on the same day. Which company did a better job of it?
Samsung vs. LG: Dueling press conferences
If you spend hundreds of millions developing a new flagship phone, you better make its introduction something special!
A closer look at Samsung's Gear 360 camera
360-degree video is going to be all the rage this year, so of course Samsung's got a product to create it.
Samsung's Gear 360 camera takes photos and videos that surround you
Samsung hopes to democratize VR content creation with an this affordable accessory.
HP sets sights on business users with Elite x3 smartphone
Computerworld Senior Editor Matt Hamblen goes into detail with HP's business-friendly Elite x3 smartphone.
Tracovino's smart sensors give winemakers an efficiency boost
Who knew that big data and networking could help you make better wine?
Samsung Galaxy S7, HP Elite X3 target business users in dramatically different ways
Smartphones with Android and Windows 10 Mobile vastly differ when it comes to business features, as highlighted by new smartphones introduced at MWC.
Google teams up with carriers to speed adoption of Rich Communication Services
An Android client is in the works, which should spread adoption of this major upgrade for mobile messaging.
Sony's Xperia concept gadgets are weird and underwhelming
The Japanese company gets some credit for attempting to innovate, but better luck next time.
Mobile World Congress ArticlesNext Page


text:
Ji'li'lu was a place with city-states were the prophet Mekhem learned how to build roads. This knowldege was used to expand the Jewel of the Desert, Medinaat al-Salaam. [1]
J'li'lu's fire Edit
The Yodotai Empire learned about the J'li'lu's fire, the secret of the thunderous fireballs. They were used in 1132 during the Shattering of the Jewel. [2]
- ↑ Legend of the Burning Sands Roleplaying Game, p. 91
- ↑ J'li'lu's Fire (LBS - The Awakening flavor)
|This article is a stub. That means that it has been started, but is incomplete. You can help by adding to the information here.


text: T'Mura was a female Vulcan Starfleet lieutenant (j.g.) who, during the Borg Invasion of 2381, was assigned to the USS Monarch. T'Mura and her husband, Lieutenant (j.g.) Valak, were in the midst of Pon farr when the Monarch engaged the Borg at Lorillia. T'Mura was killed in the battle, leaving Valak's emotional control destroyed. (ST novel: A Singular Destiny)


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Wipeout 2
Surf the wave, fly off the lip and perform soem radical moves and tricks.
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Duck hitches a ride on a surfboard.
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Learn To Fly
One Penguin Takes it personally when he is surfing the web and stumbles upon a web site telling him ...
Learn To Fly


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At this page you can see several examples of waves mask usages.


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Elizabeth Raby
Poems that explore how that girl became this woman, how the experiences of the child shaped the preoccupations, the eyes, the head and the heart, of the adult. Poems that explore the whole mysterious cycle, with stops for grief and beauty along the way; that prepare the poet for the sweet hold of earth, each life a seed in the dark. Christopher Bursk, winner of the 2004 Donald Hall Prize in Poetry for The Improbable Swervings of Atoms, writes of This Woman "I found myself delighting in poem after poem–and in the way the poems spoke to each other. I know no one better able to renew in even the most jaded of us a sense of wonder and an appreciation of the fragile balance of our lives. Elizabeth Raby faces the terrible and yet she keeps returning to a brave and determined affirmation of the now."
for a larger image of the cover…
cover art: sculpture by Susan Opie, photographs by Andrew Douglas
isbn 9780983009191


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Terror In Resonance - Ultimate Edition [DVD + Blu-Ray]
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Legendary director of Cowboy Bebop, Shinichiro Watanabe, and famed composer Yoko Kanno are back with a suspense-filled intellectual thriller!
Synopsis: In an alternate version of the present, Tokyo has been decimated by a shocking terrorist attack, and the only hint to the identity of the culprit is a bizarre video uploaded to the internet. The police, baffled by this cryptic clue, are powerless to stop the paranoia spreading across the population.
While the world searches for a criminal mastermind to blame for this tragedy, two mysterious children children who shouldn t even exist masterfully carry out their heinous plan. Cursed to walk through this world with the names Nine and Twelve, the two combine to form Sphinx, a clandestine entity determine to wake the people from their slumber and pull the trigger on this world.
The complete series in English and the original Japanese language audio with subtitles.
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Product Details
Release Date: 25/04/16
BBFC Cert: 12Format: Blu-ray and DVD
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Skip to Content
Home > Wellness > Health Library > Cancer: Home Treatment for Sleep Problems
treatment may be all that is needed to relieve sleep problems caused by cancer
or the side effects of chemotherapy or radiation therapy. If your doctor has
given you instructions or medicines to treat sleep problems, be sure to follow
them. Check with your doctor before using any
nonprescription medicines to help you sleep.
There is evidence that therapeutic massage improves sleep for people who are having cancer treatments. Massage may also reduce pain, anxiety, and other symptoms.footnote 1
Mind-body therapy, such as meditation, relaxation, and cognitive-behavioral therapy, often are helpful for people in cancer treatments. Movement-based mind-body therapy, such as yoga and tai chi, have been found to improve sleep quality.footnote 2
If one
or more of the following symptoms occur during home treatment, contact your
Freeman L (2009). Massage therapy. Mosby's Complementary and Alternative Medicine: A Research-Based Approach, 3rd ed., chap. 13, pp. 364–388. St. Louis, MO: Mosby Elsevier.
Ulbricht CE (2015). Complementary, alternative, and integrative therapies in cancer care. In VT DeVita Jr et al., eds., DeVita, Hellman, and Rosenberg's Cancer Principles and Practices of Oncology, 10th ed., pp. 2163–2174. Philadelphia: Walters Kluwer.
ByHealthwise StaffPrimary Medical ReviewerE. Gregory Thompson, MD - Internal MedicineSpecialist Medical ReviewerMichael Seth Rabin, MD - Medical Oncology
Current as ofJuly 10, 2015
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text:
Portions of this information are based on facts provided by the arrested individuals.
Portions of this information are based on facts provided by the arrested individuals. Those individuals have been booked with, not convicted of, the offenses shown. All accused should be presumed innocent until proven guilty.
July 6
Terrebonne Sheriff's Office
Darlene Margaret Thibodaux, 60, 273 Monarch Drive, Houma, DWI first offense, crossing center line.
Jose Luis Rodriguez, 44, 1408 Brooke St., Houma, resisting by refusing to show identification, resisting an officer.
Gustavo Flores Barrera, 30, 223 Fairmont Drive, Houma, DWI first offense, speeding, turning illegally at intersection, unlicensed driver.
Luis Alonso Molina, 49, 105 Westwood Drive, Houma, DWI first offense, crossing center line, unlicensed driver.
Todd Kendall Hartman Jr., 24, 1520 Grand Caillou Road, Houma, aggravated flight from officer.
Kirstie Lyn Smith, 24, 3808 Charles Ave., Groves, disturbing peace by fighting.
Ray Anthony Carlos, 58, 8176 Big Cypress St., Houma, second degree murder.
Jermie Juawon Coleman, 27, 1113 Willow St., Houma, felony carrying illegal weapon.
Cody James Authement, 27, 386 Monarch Drive, Houma, domestic abuse with minor present.
Claudette Marie Kingrey, 34, 9264 Port Au Prince, Houma, DWI first offense, crossing center line.
Seth Joseph Carreker, 20, 135 Tulip Drive, Houma, drug paraphernalia, possession of marijuana, contempt of court, interfering with state police, no seat belt in use.
July 7
Terrebonne Sheriff's Office
Marcel Michael Waguespack, 24, 404 Broadmoor Ave., Houma, illegal possession of stolen goods greater than $500.
Jamie Lynn Fabre, 31, 151 Zachary Lane, Lockport, failure to appear.
Michael Stacy Yawn, 24, 13175 Whit Holden Road, Walker, holding for other agency.
Danny Wade Melton, 43, 4457 Popps Ferry Road, Iverville, holding for other agency.
Durell Rashad Smith, 27, 406 Champion St., Gray, failure to appear, domestic abuse with minor present.
Wilbert Gray Jr., 55, 422 Brocata Lane, Racleand, possession of schedule II drugs.
Ricky Anthony Solet, 53, 2867 Express Blvd., Houma, DWI first offense, careless operation, no insurance, unlicensed driver, registration expired, open container in vehicle, drug paraphernalia, vehicle license required.
Gerald Lee Duncan, 48, 202 Ridgeway St., Thibodaux, theft of goods under $500.
Brittany Lynn Tribe, 22, 612 Roosevelt St., Houma, contempt of court.
Derek Paul Price, 33, 3816 Country Drive, Bourg, theft of goods over $500.
Michell Marie Robling, 39, 101 Mary St., Gray, failure to appear, contempt of court, holding for other agency.
Peter Long Nguyen, 28, 115 Odelia Circle, Houma, distribution of schedule I narcotic, financial transactions involving drug proceeds, failure to appear, probation violation.
Dylan Paul William, 20, 3010 Sycamore Drive, Houma, proper equipment on vehicle, vehicle license required, owner vehicle registration, motorcycle endorsement needed, no brake tag, no safety helmet, no eye protection, no insurance, resisting arrest by flight, careless operation, possession of controlled dangerous substance I, drug paraphernalia.
Amy Ann Jones, 38, 114 Chauvin Drive, Raceland, two counts of theft of goods under $500, organized retail theft, holding for other agency.
Lacy Theresa Blanchard, 32, 219 T Leigh Drive, Houma, theft over $500.
Ryan Michael Lebouef, 24, 121 Treasure Drive, Raceland, possession of controlled dangerous substance I, drug paraphernalia, use of firearm with controlled dangerous substance.
July 8
Terrebonne Sheriff's Office
James Junior Ray Jr., 41, 513 Eliza St., Houma, probation violation, possession of marijuana.
Christopher Allen Nace, 49, 3700 Reba St., Gray, disturbing the peace drunk.
Trey Lorenz Ross, 21, 401 Marietta Place, Gray, parole violation.
Preston Frankeith Allen, 26, 115 Johnson Ridge, Schriever, two counts of stalking, simple burglary of a home.
Gordon John Himel, 61, 201 Alex St., Houma, simple battery on the infirm.
Kidd Michael Babin, 37, 329 Allen St., Houma, failure to appear, holding for other agency.
Jonathan Paul Lirette, 18, 303 Christine St., Chauvin, two counts of failure to appear, conspiracy to possess controlled dangerous substance.
Michael Joseph Leger Jr., 33, 951 La. 55, Montegut, possession with intent to distribute schedule I drugs, drug paraphernalia.
Richard Allen Van Leuven, 31, 3954 Greatwood St., Gray, failure to appear.
Lacy Theresa Blanchard, 32, 219 T Leigh Drive, Houma, contempt of court.
Ronnie Vincent Glynn, 25, 433 Lake Long Drive, Houma, failure to appear.
Trey Lorenz Ross, 21, 401 Marietta Place, Gray, domestic abuse battery.
Colby Michael Boutain, 23, 306 College St., Napoleonville, failure to appear.
Lafourche Sheriff's Office
Dusty Paul Lebouef, 29, 121 Delgrandile Lane, Golden Meadow, three counts of contempt of court.
Brent J. Bouzigard Jr., 19, 123 Washington St., Golden Meadow, carnal knowledge of a juvenile.
Derek Baudoin, 33, 1735 Lacroix Drive, Houma, contempt of court,
Craig Gerard Bychurch Jr., 32, 142 Wayne Ave., Houma, fugitive.
Timothy Lloyd Matherne, 56, 291 Leblanc Drive, Lockport, three counts of contempt of court.
Shane Paul Eschette, 47, 233 Cypress Court, Gray, domestic abuse battery, theft of a motor vehicle.
Thibodaux Police
Dominique Johnson, 21, 131 Cancienne Road, Napoleonville, two counts of contempt of court.
Charles Edward Henry, 22, 817 N Eighth St. Thibodaux, three counts of contempt of court.
Delvin Charles Beckett, 21, 1281-A St Charles St., Thibodaux, domestic abuse battery with child endangerment,
Tawan Rene Every, 24, 619 Cypress St. Thibodaux, contempt of court.
Lockport Police
Brian Curole, 19, 303 Comeaux Drive, Lockport, second degree battery.
State Police
Johnnie Bennett Jr, 34, 235 Ayo St. Raceland, contempt of court.
July 9
State Police
Leon Shelby, 32, 205 Southland Circle, Houma, second-offense DWI, Driving On A Roadway Laned For Traffic.


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What is JotForm?
JotForm is a free online form builder which helps you create online forms without writing a single line of code. No sign-up required.
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How to place form fields one below the other?Asked by agl42195 on March 19, 2015 at 07:47 AM
name / Surname / telephone / Date
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Awww, little precious thing!! I wonder why her mother rejected her?
Awww, little precious thing!! I wonder why her mother rejected her?
I figured it out. Thanks though.
What a little sweetie!
><((((º>·. ¸¸. ·´¯`·.¸¸><((((º>><((((º>`·.¸¸.··´¯`·...¸><((((º>¸.·´¯`·.. ><((((º> `·.¸¸.·´¯`·...¸><((((º>
Meryl doesn't even try anymore. She just calls Lanvin and asks for curtains with a belt.~Bitter
Can we interest you in Leann Rimes? She has a nice little cadre of fans you'd probably enjoy.~ Pecan Pie
That article made me a little teary. Such a precious little thing.
Did you know that an anagram for "Conscious Uncoupling" is "Iconic Uncool Pus Guns"? - MohandasKGanja
Must be a very common occurence. Conan had Nigel Marvan on last night and he had a little boy spider monkey who was clinging to a stuffed animal from Dallas. So damn cute!
I am going to come and burn the fucking house down... but you will blow me first."
It seems to be quite a common occurrence for the monkeys kept in zoos.
She is just adorable.
Life is short. Break the Rules. Forgive Quickly. Kiss Slowly. Love Truly.
Laugh Uncontrollably. And never regret ANYTHING that makes you smile.
- Mark Twain
Maybe they remind them too much of the dad
There are currently 1 users browsing this thread. (0 members and 1 guests)


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Oh My!! Did He ask What???????
Ok I am at the bakery this morning (craving carrot cake and cannolies) so i stand on line and there is this guy asking for a "Carrot cake" but what came out his mouth next was just CRAZY and my ears couldn't believe it, he asked the young lady
"excuse me miss is the carrot cake contain any meat if so which one, any potatoes or other veggies?" My stomach twist and turn and i just walked out to get some fresh air i couldn't LoL in his face! Thank god i didn't lose my space on line!!!
Lol! I wonder where he used to get his carrot cake from.
LOL, Ew no meat in carrot cake. That's weird.
The young lady face was " EXCUSE ME SIR, DO YOU NEED A CARROT POT PIE" and the guy say NO i just want to know about that CARROT CAKE and repeat himself! so THE young lady call the owner and the owner said " DO YOU WANT IT WITH BEEF OR PORK OR CHICKEN" if so you most go to the corner restaurant and place your order there!!! LOL
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Seattle University
Home of the Red Hawks
Red Hawk Pride !
Campus History and Origins
Seattle University or commomly known as Seattle U is a Jesuit Calothic based university in the Northwestern United States in the Capitol Hill neighborhod of Seattle,Washington.SU is the largest independent university in the Nothwest US with over 7500 students enrolled as undergraduate and graduate programs.It is part of the 28 member institutions of the Association of Jesuit Colleges and Universities. It is also the 5th best school in the West.
It was founded by Adrian Sweere in 1891 when he took over a small persih near downtown Seattle.
In 1898 it was renamed Seattle College and granted its first bacholars degree 11 years later. At first the school was both a high school and college. In 1931 it also became a nigh school for women.
In 1948 got renamed Seattle University and in 1933 it established Seattle University School of Law.
In 2009 they completed the largest capital campaign raising almost 169 million dollars.
The campus is 50 acres and have recycling and conservation programs and are a pesticide free campus.
Also 5% of their student pop. is Hispanic or Latino
Mascot was not Red Hawks until 2010
Seattle University Fight Song
Admission Requirements
SAT-(25-75th Percentile)
Critical Reading: 520-640
Math: 530-640
Writing: 520-620
ACT-(25-75th Percentile)
Composite: 23-29
English: 23-30
Math: 23-28
Tuition and Costs
Tuition and cost per semester and per year:
Year costs :
Tuition and fees:$36,465.
Books and supplies:$1,485.
Personal Expenses:$600
Room and Board:$10,545
Total:$ 49,655
Campus Life:
Quadstock is a annual music festival that almost all students go to and love to attend.
My Career
For my degree i need to get my bachelors and masters in psychology and then get my Dr. in psychiatry. I will need to take some medical school courses. The difference between psychology and psychiatry is that psychiatry allows the person to give patients medications and treatment.
Degree Plan:
I. Core Curriculum Requirements
- ENGL 110 - College Writing: Inquiry and Argument 5
- PHIL 110 - Introduction to Philosophy and Critical Thinking 5
- HIST 120 - Origins of Western Civilization 5
- ENGL 120 - Introduction to Literature 5
- MATH (filled by MATH 110 in major)*
- Lab Science (filled by BIOL 161/171 in major)*
- Fine Arts (one approved 5-credit course) 5
- PHIL 220 - Philosophy of the Human Person 5
- Social Science I (not psychology) 5
- Social Science II (not psychology and different discipline from Social Science I) 5
- Theology and Religious Studies Phase II (200-299) 5
- Ethics (upper division) 5
- Theology and Religious Studies Phase III (300-399) 5
- Interdisciplinary 3 to 5
- Senior Synthesis filled by PSYC 489
- II. College of Arts and Sciences Requirements
- Modern Language 115, 125, 135, or equivalent (15)
- HIST 121 - Studies in Modern Civilization 5
- HIST 231 - Survey of the United States 5
70 credits in psychology, including:
- PSYC 120 - Introductory Psychology 5 *
- PSYC 205 - Writing for Research in Psychology 5 *
- PSYC 303 - Statistics and Research Methods I 5
- PSYC 305 - Statistics and Research Methods II 5
- PSYC 370 - History and Schools of Psychology 5 *
- PSYC 403 - Advanced Statistics and Experimental Design 5 *
- PSYC 489 - Senior Seminar 5 *
- PSYC Electives (25)
PSYC 240 - Physiological Psychology 5
Cover Letter
Isabella Green
A Helping Hand Organization
2311 Riverbed Dr.
May 19,2015
Good evening Mrs.Green,
I am interested in joining your organization to help children with psychological problems after seeing your presentation at Seattle University last week.
I am currently in my senior year at Seattle University and I am majoring in psychiatry. I was very interested to know how much your organization helps children in need of serious help. I want to stay local and be able to work with all kinds of people but I think that helping children is more in my comfort zone since I have four sisters. I am eager to join your organization and help the innocent kids that are suffering for no reason. I feel like my skills with children and my understanding persona I think I can really help the children and bring a new happiness to the children. I have had experiences with really troubled kids while volunteering at other organizations that would make me a very good candidate for the job at your organization as a child psychiatrist. I feel like this to me is a priority some might say it is a hobby but I think it will just prepare me for when I grow as a psychiatrist and it is so important to me to be able to help people.I believe that with my social skills and my experience with children I can bring comfort and relief to these kids that are desperate for help and want to keep going in a normal life.
I have noticed all the good that this organization has done and how much support it recives from the community and I want to become part of this Helping Hand family.It will be an honor to work with others with the same passion and with kids that have a thirst for a healthier and normal life.
Thank you in advance for any opportunities you can give me.
Cameron Martinez
2315 Reign Dr.
Letter of Recommendation
To Seattle University,
I recommend Cameron Martinez for Seattle University because she is an excellent student willing to learn and grow in college. Ms. Martinez is one of my best students in her class she is a hard worker and will do anything for her education. I have been with her for almost a year and I have seen her grow and become a smart and independent student. She rarely ever has discipline issues and will respect the professors at your school as she has for me.
Ms. Martinez has many talents, one of them is being a very intelligent writer, she wants to go to your school to become and psychiatrist she believes that this school will help her achieve her dream. I have seen look to the future and the desire to go to college and educate herself. I once told her that knowledge is the one thing no one can take from you and that college is the one way to get that knowledge. Of course she wanted to go to college before I told her this but this encouraged her to be the best she can a make a future for herself. Her skills are, she can listen and pay attention in class, push herself to do school work, and an is intelligent thinker.
The reason the Ms. Martinez has been a wonderful student this year because she does think about the future and she pushes herself hard because school is her number one priority right now. Her determination to go to a university astounds me, most of my students only look in the present and don't worry about the future. This is why I recommend Cameron Martinez because she is not like other students and your school will watch Mr. Martines be a great candidate in this certain field of study. You can contact me at email@example.com or at (915)-277-6993.
Ellinore Lightheart
English Teacher
El Dorado 9th Grade Academy
El Paso TX 79938
Email: firstname.lastname@example.com
Cameron Martinez
79938 Reign Dr. Seattle, Washington 87456
Phone: 799-231-6785 E-Mail: cmarti7812@gmail
My objective is to become a child psychiatrist and help people with mental issues, and build organizations all over the U.S to help people and kids in crisis. The organization will also be a Safe Place for women, children, and teens.
Seattle Help Center for Teens 6/25/19-9/12/21
-In this volunteer job I got to experience working with teens children and helping them with school, personal problems and mental conditions such as anxiety and depression.
- I was an emergency contact for teens with psychological issues and was like a guardian for them.
- I gained experience in emergency situations and went through drills on how to help teens in extreme and dangerous situations.
Seattle Mental Hospital 10/2/21 -Present
- I was an intern at the mental hospital and worked with all kids of people from different ages.
-I worked in dangerous and stressful situations and had to help patients calm down
- I was a therapist and a social worker for people in the hospital and helped determine their conditions and treatments.
El Dorado/Pebble Hills High School 2014-2018
I was in an extracurricular activity that challenged me and I competed with schools all around the city. I took multiple tests even in economics. I was also in UIL impromptu speech and maintained a 4.0 GPA.
Seattle University 2018-2022
I studied psychology and did volunteer work near the school at help centers and also maintained an internship while attending the university. I learned how to deal with emergency situations and how to make a person open up about their problems.
My skills all revolve around being able to connect with people and help them. I know how to make a person open up because I make a connection with them that builds trust. I can help a person find their problems and I do not force a treatment plan I make sure they can actually achieve the goal of mental health. I am very friendly and am very good around children and have a very good understanding of how they work.
Persuasive Essay
Seattle University
From a young age i had realized my passion for helping people and analyzing every
single aspect of them. I would find out things about them they didn't even know and i was fascinated when i realized i could help them reach into the deepest parts of their mind and feelings and help them resolve any issues. I would study people intensely as if they were under a microscope and try to figure them out. I was always in people's business but it was always to help. I tried to help people through bad stages in their life and when I was 11 years old my older cousin told me I saved her life by just talking to her i decided this is what i wanted to do, I wanted to be a physiatrist. I wanted to be a different kind of superhero. Even though I knew what i wanted to be from a young age i did change my mind a couple of times. I thought for a long time that i wanted to be a novel writer because i was so wrapped up in the fictional world of books but as I matured and experienced things I realized I could do so much more then write novels.
Firstly, I have volunteered in a couple of organizations that allowed me to gain experience with mentally ill people and I have loved it. I learned that it takes a lot of patience and mental stability to care for people that are not as mentally stable as a healthy person.Some people do not want to be helped but a good psychologist or psychiatrist never gives up on someone who truly needs help. I think that I deserve to be accepted into Seattle University because I am very interested in the psychology program and I know I can be a good addition to the school. I am a good student and I like to take on challenges and expand my mind. I have a long attention span and know how to stay focused. I maintain good grades but not for praise or because it is a requirement but because i want to and think it is a reflection of the person I am.
Secondly,I know that I can bring so many great things such as programs where people volunteer and help fellow students and other people relieve stress and vent out for free so they can have someone to talk to. I want to start groups around the city of Seattle for people in crisis and make these places Safe Places so people who are having problems or no where to go can be safe and get treatment for any problems. I want to do this with my career and my ability to help people and I know that if I graduate from Seattle University and do all the things I want I will give Seattle University recognition for giving me the opportunity to achieve all my goals. I know universities look for good qualities in students that make their school what it is and I think I have those good qualities and can bring something to the school.I think that with my skills I will be a great student and i have skills that can advance me in my field of study.
I have a passion for helping people and helping them get through hard times. I want to bring consolation to people,especially to kids whose minds do not function as others and who with a little bit of help can live a normal life.I think I can help so many people if given the opportunity and I think I deserve this acceptance to Seattle University because I am a hard working and dedicated student that wants to do her best in helping one person at a time.


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Nachvorst are a highly underrated band and I'd like to help change that as much as I can. I really enjoyed their 2009 album Stills (Black Devastation Records), which was their first full-length and am equally impressed with their sophomore full-length, Silence. This time around they are less of an atmospheric black metal band as they vary their sound through incorporating a bit of funeral doom, Alcest/Lifelover post metal drifting, some serious riffing, psychedelia, and stoner vibes. All of which, in combination, yield a serious brain blur of bliss and chaos simultaneously.
Silence starts out with the 11-minute funeral doom/death doom influenced "The Serpents Tongue" that has the suffocating riffs and tone of a funeral doom song but the pace is kept throbbing with a steady bass pulse as opposed to the glacial drone typical of some funeral doom acts. The band also drifts off into a post metal stretch for the last half of the song ranging from fluid and ghostly atmospheric post metal to a mega sonic explosive free-for-all while the lead guitar wails like an eerie siren underneath the rhythmic current.
"Nightwinds" is a colossal beast of black metal that is actually border lining on some blackened sludge, in fact Black Cobra briefly come to mind. The potent ingredient on here is the infectious bassline that weaves aggressively in and out and over the mix. That bassline is also more doom and stoner than black metal but it's for that reason as well that it works so well here as it wraps around your neck pulling you into the incoming post metal undertow of black emotional fury and haunting revelations.
"Gentle Notice of a Final Breath" is another complex brew of spacey post rock/post metal haze comprised of intricate melodies bearing resemblance to a sort of a My Bloody Valentine shoe gaze, goth/death rock vibe similar to Dhampyr's White Fire Laudanum album. And yet again there's a pumping bassline, this time more deathrock and goth than doom stoner but still as powerful.
"A Way of Silence" begins with a psychedelic fuzzed out intro that builds from soft to loud with a seismic burst of distortion that gives it a good fuzzy texture that is clear and still a bit muddy giving the song an almost heavy psyche/stoner leaning with beefy guitar tones and the right amount of effect that simply put, really fucking works, especially when they start gaining momentum and alternating rhythms keeping it catchy, colossal, and grooving. The vocals during the heavy resonating portions are raspy black metal shrieks while other times the vocals seem almost like a ghostly whisper behind the simple early Cure like melody that comes into play about 6 minutes in and lasts for about 3 minutes. During this time the song builds up smoothly beneath a plume of druggy smoke as the song comes to a head with an explosively sonic and emotional ending combining raspy black metal shrieks, clean vocals behind the mix, some almost death doom growls amidst collisions of whirring distortion ending with an almost communal storm of rhythm between both guitar and drums.
It's taken me some time to fully translate the experience of listening to Silence mostly due to the diversity of their sound and trying to legitimately capture the many intricacies on here. It's also amazing to me how they mix so many styles together flawlessly into something that is breathtaking and entrancing but never loses the fury and aggressiveness behind their creations. I really hope that some of you will check these guys out and keep bands like this developing into something worthwhile.


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RECIPE SECTION - Over 10,000 Recipes
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Recommended Wine Pairing: Chablis Premier Cru Montée de Tonnerre 2007
Yields two servings
4 sundrenched tomatoes
Ciabatta bread
1 ball of buffalo mozzarella
1 glass of milk or single cream
2 tablespoons of freshly grated Parmigiano-Reggiano
Lemon zest
Basil leaves
Clove of garlic
Olive oil
Chablis wine
Toast the ciabatta bread and cut it into thin slices.
Peel the tomatoes and then blend them with the garlic clove, some salt, pepper and a drizzle of olive oil.
Pour the tomato purée in a glass.
Dice the mozzarella and blend it with the milk or single cream. If you can't get enough froth whisk it a bit. Add the lemon zest at this stage.
Set your oven to 400 degrees and drop two separate tablespoons full of grated Parmigiano-Reggiano on a non stick baking tray.
Wait till they have melted and start to brown a bit, take them out they will bring some crunchy texture to the dish
Plunge the bread sticks into the tomato purée, cover with the mozzarella froth and add a bit of pepper and basil.
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"(Tell us your experiences in 500 ..."
About: Peterborough District Hospital Peterborough District Hospital Peterborough PE3 6DA
Posted by colin (as ),
What I liked
(Tell us your experiences in 500 words or less)
What could be improved
I recently suffered a stroke and after being discharged with future test to carried out via outpatients was told by the consultant, " I will see you in six weeks with the results of the tests to hand ". I had the tests (scans) and was then sent an appointment to see the consultant four months hence, FOUR MONTHS!, to be left in limbo with the possability of suffering another stroke. I am disgusted with such lack of care especially by the people on the end of the telephone who it seems could not care less.
Response from Peterborough District Hospital 7 years ago
The Trust takes the experiences of patients and visitors to our hospitals very seriously and we aim to provide a safe, caring and effective service. However, we do recognise there are occasions when an experience may not have met the expectations of our patients or visitors and we are keen to understand how we cam make things better.
To help us continually improve our services for current and future patients and visitors we need feedback and are happy to look into any matter where a patient or visitor is disappointed with the service they received.
This feedback has been forwarded to the relevant department to look into in further detail. Please contact our Patient Advice and Liaison Service (PALS) on 01733 875847 or email email@example.com who will provide help and advice regarding any issue.
Thank you for visiting NHS Choices.
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Winchester 1894-1994 Centennial High Grade
Guns International #: 100652460 Seller's Inventory #:
Category: Winchester Rifles - Model 94 Post-64 - Winchester Commemorative Firearms
Seller's Information
When emailing or calling sellers direct, please mention that you saw their listing on GunsInternational.com
Seller: Stockjocky
Member Since: 6/7/09
State: Colorado
Country: United States
Phone: 719-227-5825
Number of Active Listings: 23
Total Number of Listings: 220
Seller: Private Seller
Return Policy: 3 day inspection and return policy on used guns.
3 days ****** RESTOCKING***RETURN FEE *****
Payment Types Accepted: Postal money orders
PRICE LOWERED. Exceptional wood new and unfired. This rifle is to celebrate 100 years of the 1894. Box is included, but may not be the original box and in poor condition. Shipping $45.00 throgh my dealer $75.00.
Price: $1,475.00
Manufacturer: winchester
Model: 1894
Caliber: 30-30
Condition: New
Metal Condition: New
Wood Condition: New
Bore Condition: New


text:
Comedy, Games & Hobbies, AutomotiveFollow
|Games & Hobbies
America's funniest auto mechanics take calls from weary car owners all over the country, and crack wise while they diagnose Dodges and dismiss Diahatsus. You don't have to know anything about cars to love this one hour weekly laugh fest.
November 28th, 2015
Episode 60 of 144 episodes
This week on The Best of Car Talk, here's a first. Ephraim went to the dealer to complain that his Audi's gas mileage was too good. Apparently, said gas mileage nearly doubled when Ephraim's fiancee began driving the Audi, so there must be something wrong with the car, right? As Tom and Ray would say, "Au contraire, piston puss!" Elsewhere, Rachel's mechanic warned her of "boulder intrusion" if she doesn't replace a broken CV boot; Pam's Toyota is dripping molten lead from the dashboard; and Al and his brother are arguing over whether it's possible to park a truck in a position from which it's impossible to move. Also, how one listener is using Car Talk to help teach English. Yes, really. All this and more, this week on the Best of Car Talk.
You'll need to sign in to write a comment.
Welcome to the Brain Training Podcast, the daily audio workout for your head. In this podcast we have two games for you, each with three rounds which get progressively harder. To enjoy the full experience, relax, and avoid distractions whilst you listen.


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Immunization Rates
Umatilla County (PDF)
Clara Brownell Middle School, the home of the Umatilla Vikings, educates approximately 320 sixth, seventh, and eighth grade students. Located in the middle of the city, CBMS serves all the middle grade students from the Umatilla area.
Clara Brownell Middle School focuses on educating students for life. The school's academics consist of core classes of reading, math, science and language arts which are all mandated state testing areas. We also offer a social studies class, special education classes and ELL classes for students gaining proficiency in learning English and learning more about our world around us. PE, music and a middle school exploratory class focusing on healthy choices are also offered to students to broaden their horizens for life opportunities. The typical day includes 8 periods and also includes a benchmark class that reinforces skills in order for students to be successful on state testing areas.
Clara Brownell offers an after school program to help reinforce skills and provide core subject area tutoring by our own staff. Students who attend 30 or more sessions during the year demonstrate growth in their academics as well as state testing areas. This program is taught by our regular teaching staff who know our students and know their needs. All students receive a hearty snack and a ride home after the program ends at 4:00 P.M.
Clara Brownell Middle School developed these shared beliefs for the students, staff, parents and the community we serve:
School Motto:
Challenging, Believing, Motivating, Succeeding
Copyright © 2017. All rights reserved


text:
On you will fall not only a barrage of zombie like creatures, but the warring factions. Explore anturazhnye cards and a lot of interesting locations such as abandoned factories, warehouses, barns and similar buildings. Particularly noteworthy are the same abandoned military base, where you will find lots of couches, barrels of them divorced in fires and other paraphernalia is certainly pleasing to the true fan.
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NANO-Antivirus → Riskware.Android.Viser.cxqinz
Comodo → ApplicUnwnt
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Rating:(494) 2.48★ 49.5%
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Let's get Educated!
The website that I chose was Education world. I chose this website because it was very visually appealing to me! There are several different resources that it provides for teachers, and it also allows us to learn more about the world. It has several articles about for new teachers, substitutes, administration, and technology. Several cultures are displayed on this website. There are not very many pictures on the website, but the pictures that they do have represent different cultures. The posts that they post are what is very culturally diverse. This website looks like it can and will be very helpful for teachers. To visit the website click the button below.