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Global Pneumatic Tire Market 2016-2020: Size, Share, Growth, Analysis, Key Trend, Demand and Forecast
Pneumatic tires are in high demand in the automotive industry. Pneumatic tires are rubber tires filled with compressed air that enhances the tires loading capacity and improves the overall performance of the vehicle. Raw materials that are used in the manufacturing of pneumatic tires include natural rubber, synthetic rubber, carbon black, steel wire, petrochemicals reinforcing materials (fabric, steel, polyester, nylon, and rayon), fabric cord and wires. The pneumatic tire market has witnessed considerable growth primarily due to significant increase in automobile production and a subsequent rise in the demand of tires in the replacement market. However, the growing trend of retreading tires and fluctuating raw material prices are factors hindering the growth of the market.
Do Inquiry For Sample Report On Pneumatic Tire Market: http://www.marketresearchstore.com/report/world-pneumatic-tire-market-opportunities-and-forecasts-49207#RequestSample
The market is segmented based on the type of sale, vehicle type, product type and geography. Based on the type of sale, the market is further segmented into OEM (original equipment manufacturer) and replacement. The replacement segment accounted for the maximum revenue share in the pneumatic tire market evaluated at $143.7 billion in 2014. This segment is expected to dominate the market during the forecast period (2015–2020). Tires are basically categorized into radial and cross-ply tires, with radial holding around 68% of the total market share by value. Based on the vehicle type, the market is segmented into two wheelers, four wheelers, aircrafts and others (industrial and agricultural vehicles). Presently, four wheelers tire segment is the highest revenue-generating category and is expected to maintain its dominant position throughout the analysis period. The key geographic regions covered in the report include North America, Europe, APAC and LAMEA.
Several companies manufacture novel tires with outstanding tractions and better grip properties suitable for all surface types. The pneumatic radial tire "ContiRT20", a new product by Continental AG, provides exceptional stability during the lifting and transport of load in vehicles. Bridgestone offers an 8 inch diameter tires, particularly for use in industrial vehicles.The prominent players in this market are Michelin, Continental AG, Bridgestone Corporation, Cooper Tire & Rubber Company, The Goodyear Tire and Rubber Company, Hankook Tire Co. Ltd., The Yokohama Rubber Co. Ltd., Sumitomo Rubber Industries Ltd., Pirelli & C.S.p.A, Kumho Tire USA., Inc.
- The report provides an in-depth analysis of the pneumatic tires market and offers current and future trends to identify lucrative investment pockets in the market
- The report identifies the key drivers, opportunities and restraints that shape the market and provides an impact analysis during the forecast period
- Porter's five forces analysis highlights the potency of buyers and suppliers participating in this market. This would further offer a competitive advantage to the stakeholders in making profitable business decisions; thus, helping them to strengthen their supplier and buyer networks
- Current and future trends have been outlined to determine the overall attractiveness and highlight the profitable trends in order to gain a stronger foothold in the market
- Market estimation of geographic segments has been derived from the current market scenario and expected market trends
Read Complete Table Of Content On Pneumatic Tire Market: http://www.marketresearchstore.com/report/world-pneumatic-tire-market-opportunities-and-forecasts-49207#tableOfContent
The market is segmented on the basis of type of sales, vehicle type, product type and geography.
Global Pneumatic Tires Market—By Type of Sales
- Replacement tires
Global Pneumatic Tires Market—By Vehicle Type
- Two Wheelers
- Bicycle
- Motorcycle
- Four Wheelers
- Passenger Cars
- Commercial Vehicles (Trucks, Buses)
- Aircraft
- Others (Industrial Vehicles, Agricultural Vehicles and Off-Road Vehicles)
Global Pneumatic Tires Market—By Product Type
- Radial Tires
- Cross-ply Tires
Global Pneumatic Tires—By Geography
- North America
- Europe
- Asia-Pacific
- Michelin
- Continental AG
- Bridgestone Corporation
- Cooper Tire & Rubber Company
The Goodyear Tire and Rubber Company
- Hankook Tire Co. Ltd.
- The Yokohama Rubber Co. Ltd.
- Sumitomo Rubber Industries Ltd.
- Pirelli & C.S.p.A
- Kumho Tire Co., Inc.
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subset: commoncrawl


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- Description
An ideal accompaniment to sweating it out in the spring chill, the Silver Ridge Short Sleeve blends simple aesthetics and progressive performance elements. Omni-Wick® advanced evaporation keeps you cool and comfortable at the height of sweat-infused activity and the long, sleek cut with flattering seam lines turns up the feminine-factor. Omni-Shade® sun protection creates a comforting barrier between your skin and harsh UV rays and a flip-up collar provides extra protection for your neck. Offered in a range of super versatile colors that pair easily with shorts, khakis or denim.
- Fabric: 53% nylon/47% Tactel® cylon Silver Ridge Stretch ripstop, 53% nylon/43% Tactel® nylon/5% polyester seersucker, 57% recycled polyester/43% polyester
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|Message view
|« Date » · « Thread »
|« Date » · « Thread »
|"Joe Bowser (JIRA)" <j...@apache.org>
|[jira] [Commented] (CB-1185) When Application is placed in background and resumed, the UI is frozen
|Thu, 02 Aug 2012 21:47:02 GMT
[ https://issues.apache.org/jira/browse/CB-1185?page=com.atlassian.jira.plugin.system.issuetabpanels:comment-tabpanel&focusedCommentId=13427647#comment-13427647 ] Joe Bowser commented on CB-1185: -------------------------------- I was hitting the native menu button and navigating through there, because that's what it said on the ticket, but yeah, I can use Drink Up as well. It might be a memory usage thing, although the Galaxy Nexus is my personal device running all sorts of crap. (I do keep it on stock for testing). > When Application is placed in background and resumed, the UI is frozen > ---------------------------------------------------------------------- > > Key: CB-1185 > URL: https://issues.apache.org/jira/browse/CB-1185 > Project: Apache Cordova > Issue Type: Bug > Components: Android > Affects Versions: 2.0.0 > Environment: Jelly Bean 4.1, ICS 4.0.x > Reporter: Greg > Assignee: Joe Bowser > > When using PhoneGap 2.0.0 on ICS or JellyBean, the application freezes up after you set the app to the background or turn of the screen. After around 3-7 seconds, the application unfreezes and pretty much causes a panic and usually crashes. No error reports have been submitted. > Here is how you re-produce the issue: > 1. Download Untappd - V2.0.4(https://play.google.com/store/apps/details?id=com.untappdllc.app) > 2. After logging in stay on the Friends tab > 3. Turn the the screen off and wait about 3-7 minutes > 4. Turn the screen back on, and the interface should be frozen. > Another possible path to re-producing the issue: > 1. Download Untappd - V2.0.4(https://play.google.com/store/apps/details?id=com.untappdllc.app) > 2. After logging in stay on the Friends tab > 3. Go back to the home screen then use other apps for about 3-7 minutes. > 4. Go back into Untappd, and the interface should be frozen. > When the app is frozen, native menu buttons will not nor any options in the UI. > Would love to see if anyone can replicate this. I've tested this on Jelly Bean 4.1.x on a Samsung Galaxy Nexus, but users have been having this problem majority on ICS (4.0.x) > Thanks, > Greg -- This message is automatically generated by JIRA. If you think it was sent incorrectly, please contact your JIRA administrators: https://issues.apache.org/jira/secure/ContactAdministrators!default.jspa For more information on JIRA, see: http://www.atlassian.com/software/jira
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Property Description
4-bedroom, 4 and 1/2 bathrooms. Accommodates up to 8 guests comfortably and has a fully equipped kitchen. This townhome is equipped with high-speed wireless internet all throughout the unit, free of charge.
**PLEASE NOTE: Summerville Resort is a BRAND NEW community, please excuse our appearance while we are under construction.
Guest access
Summerville Resort is a community with resort style amenities. You will have a public pool which is heated year round. A fitness center perfect for staying in shape during your vacation. Kids play area which keeps the little ones occupied while you are enjoying your workout. A playground where kids can burn off that last bit of adrenaline caused by spending the day at the parks. And last but not least, a dog park, where your little furry family member can enjoy themselves.
Interaction with guests
Summerville Resort does not have a 24-hour check-in desk. Our hours of operation are 10 am to 5 pm. If you arrive after our normal hours of operation, you will go directly to the home and we will be available to assist you once we have arrived the following morning. We are also closed on the weekends.
The neighborhood
Summerville Resort, is located a short distance away from the heart of the Disney World area where guests will take pleasure in the advantages of onsite amenities, nearby shopping, dining, and the world-famed parks. Some townhomes include barbecues and Jacuzzi.A beautiful clubhouse with comfortable lounges and a resort style swimming pool which are perfect for year round entertaining, along with a kid's park and plenty of green spaces.
House Rules
No smoking
No parties or events
Check in is anytime after 4PM+ More


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A Florida judge has ruled against George Zimmerman in his defamation suit against NBC Universal, reports the Orlando Sentinel.
"There exists absolutely no clear and convincing evidence that defendants knew that the information published was false at the time it was published, or recklessly disregarded the truth or falsity of those statements," wrote Judge Debra S. Nelson, according to the Sentinel's account. She also pushed aside contentions in Zimmerman's complaint that he suffered emotional distress as a result of the NBC News reports.
At issue in the case were several broadcasts from NBC News that edited the 911 call that Zimmerman had made not long before shooting Trayvon Martin on the night of Feb. 26, 2012 in a subdivision in Sanford, Florida. As a result of edits by NBC News, Zimmerman sounded as if he had volunteered that Martin is black. The full tape reveals that he was asked by the dispatcher whether the person he was following was "white, black or Hispanic?" Zimmerman's complaint contends that NBC News knowingly misportrayed Zimmerman, who was acquitted last year of second-degree murder.
Nelson's summary judgment in favor of NBC News follows a June 19 hearing in the matter and a March filing by NBC Universal seeking dismissal of the case. The network argued that Zimmerman was a public figure by virtue of his history as a neighborhood watch activist prior to the shooting of 17-year-old Trayvon Martin. According to the Sentinel, Nelson sided with this argument, noting that Zimmerman had participated in a public protest over police issues as far back as 2010.
None of this is to suggest that NBC News didn't commit significant journalistic mistakes. It was forced to issue a public apology for the mal-editing and it fired two employees as well. More to come on this development.


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Advance 5778; ca. 1951; Misses skirt, simple to make slim skirt View 1 has top stitched patch pockets with high front curved waistband. View 2 soft front pleats and hip pockets.
Links to reviews/blog posts Edit
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Gallery Edit
[insert your photos of this pattern made up]
Wishlist Edit
[insert your username, and make sure your preferences allow for people to contact you via e-mail. Do not list your email address here!]


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After week 2 games and business concluded, we're left with 8 undefeated teams in this NFL season. Five in the AFC (Patriots, Ravens, Steelers, Texans, Broncos) and three in the NFC (Giants, Eagles, Vikings). More
An AFC East divisional battle takes hold of Thursday Night Football, as both the Buffalo Bills and the New York Jets are coming off losses, hoping to avoid another one that might put a serious dent into both teams playoff aspirations. More
Week 2 of the college football season was supposed to simple: Only two real threats of upsetting ranked teams, and plenty of easy games for the rest. Teams like Alabama, Ohio State and Michigan made it look easy. Others, like Georgia and Clemson struggled with some very weak opponents, which could hurt them in the rankings. Others, like TCU and especially Oklahoma State, fell into the upset trap, which will probably move them from the polls, at least for one week. More
Week 2 of the college football season offers very little in terms of upset potential big, ranked clashes, without a single game of two ranked teams. However, finally getting to see The Battle at Bristol between Virginia Tech and Tennessee happen is something to look forward to, while Arkansas coming to spoil the season for TCU is probably the other game to look forward to if you're looking for parity. More
The second week of the NFL preseason was concluded with a busy Saturday that included the Buffalo Bills shutting out the New York Giants, Cam Newton looking great in a Carolina Panthers win, Blake Bortles throwing two touchdown pass in a Jacksonville Jaguars loss, and Jared Goff tossing a late winner for the undefeated Los Angeles Rams. More
In a short day of action, the Dallas Cowboys stood out with another terrific performance from backup quarterback Dak Prescott, involved in four touchdowns, while Tony Romo had a quiet preseason debut. Colt McCoy looked pretty good for the Redskins, still without Cousins in their preseason games, while no offense went the San Diego Chargers way against a rough looking Arizona Cardinals team, as both teams failed to score an offensive touchdown. More
The NFL Preseason began its second week of action, with the best starting quarterback performance belonging to Robert Griffin III, despite the Cleveland Browns losing to the Atlanta Falcons, throwing two touchdown passes, one of them to Terrelle Pryor. Jimmy Garoppolo looked good in a New England Patriots win, mostly against the lesser defense, and Russell Wilson looked surprisingly rusy in a Seattle Seahawks loss. More
In the season's second edition of the Power Rankings, the top doesn't seem different: New England Patriots and Green Bay Packers as the likely Super Bowl teams, with the Arizona Cardinals and Cincinnati Bengals posing the biggest threats, although if the Dallas Cowboys survive their injury scare, they should be counted in too. The bottom is filled with new names, with the Houston Texans and Chicago Bears making it difficult to choose who is worse. More
The Super Bowl champions New England Patriots keep putting up points, this time on the Buffalo Bills to improve to 2-0, like NFC favorites Green Bay Packers in a comeback win against the Seattle Seahawks (winless) and the Dallas Cowboys, looking impressive while beating the Philadelphia Eagles, but also losing Tony Romo for quite a while. More
The top 3 remains unchanged following week 2 as Ohio State, Alabama and TCU cruise against weak teams. Michigan State make a small but meaningful jump after beating Oregon, who along with Auburn took the big plummets of the week, as the Tigers struggling against an FCS team costs them 12 spots. BYU, Oklahoma State and Northwestern make their first appearances in the top 25 this season, filling in for three SEC teams that dropped out: Tennessee, Arkansas and Mississippi State. More


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Doctor insights on:
I Had Cryosurgery On My Cervix 4 Weeks Ago Is It Safe For Me To Take A Bath
Will i end up having cervical cancer I have been having pain in my lower abdomen were my cervix and uturus is. I have had my IUD in for three years now. I had a pap smear a few weeks ago and the doctor said that my IUD is in good place and seems to be d
You : You need to discuss the results of your pap smear with your doctor again so you better understand what was found. Sometimes a test is done with the pap smear to determine if the cerix is infected with a strain of hpv that would put you at a higher risk for cancer and sometimes a special examination of the cervix called a colposcopy is needed to double check the area. Thankfully, many, many women who have abnormal cells will not develop cancer. ...Read more
Bathing (Definition)
Anything dropped in a fluid filled compartment is said to be bathing. The most common is the human body in a tub, but you can bathe your arm or leg at certain times (and your pets). Food soaked in savory fluid is also said to be bathing (such as bathing rama ...Read more
I had cryosurgery on my cervix 4 weeks ago. Is it safe for me to take a bath?
Probably: You should always ask your doctor, but generally it is not usually a problem. ...Read moreSee 1 more doctor answer
Can you take a bath the same day after having cryosurgery done?
Yes: You have to keep area clean and dry. ...Read moreSee 1 more doctor answer
Can cryotherapy make my cervix slough for four days?
Yes: Cryotherapy destroys through "freezing" 5 to 7 millimeters of its' surface and will slough tissue in a watery discharge for several days. It is used to treat abnormal cells called cin(dysplasia). ...Read more
Why are we told not to take a bath during a miscarriage when women give birth in water every day when their cervix is dilated?
Water Birth: Water birth is process of giving birth ina tub of warm water and it is safe and chosen by few moms.Not every doctor considers it safe.But it can be done in hospital as some hospitals offer this alternate way of birth.Not many studies have been done about its safety.There is a risk of infection if water is contaminated, same as during miscarriage. ...Read more
I'm having a cryosurgery on my cervix done tomorrow. How does the procedure work?
Freezing: Liquid carbon dioxide or nitrous oxide are used to supercool a metal probe that is placed on the cervix. The abnormal area of the cervix is frozen, allowed to thaw, and then frozen again. Cramping is not unusual during the procedure. ...Read moreSee 1 more doctor answer
I had cryosurgery on my cervix on 10 29 I have been spotting ever since then is this normal. Also started getting a yellow color discharge. ?
Cryosurgery: Some of this can be normal but if you have questions call or see your doctor. ...Read moreSee 1 more doctor answer
1 week before period I always get brown discharge. I'm on birth control pills, and I've had cryosurgery on my cervix already. Why is it happening stil?
Vaginal discharge: Yes you should go back to see your Dr and get checked again. Get a pelvic exam. May be there is some inflammation or infection . Better get examined. ...Read more
Had cryosurgery on 10/30 on my cervix I have continued to spot every day since that sex has become very painful to the point of tears dr won't help?
See another doc..: I am sorry to hear of your trouble. Cryosurgery of the cervix done 1 month ago should have healed by now. I am not too concerned about a bit of spotting because the tissue of healing cervix is thin and easily traumatized with intercourse. The severe pain is really concerning as this suggests possible infection/cervicitis or endometritis etc...See you family doc or another gyn doc asap. Good luck. ...Read more
I had my cryosurgery a few days ago. I was told to expect a watery discharge but til now have not experienced any. Is that normal? My doctor only froze my cervix for two minutes, was it suppose to be done longer?
Different protocols: Not everyone has a watery discharge. We warn people about it because it can otherwise be a bit of shock. There are different protocols for freezing the cervix. In my practice, I either use a single freeze that lasts 5 minutes or freeze for 3 minutes, allow it to thaw and then freeze again for 3 minutes. Best wishes! ...Read more
Cryotherapy (Definition)
Cervix cryosurgery is a surgical treatment to freeze and destroy abnormal ...Read more
Cervix (Definition)
The uterine cervix is the opening of the ...Read more


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Profumo has classic Genovese basil flavor, perfect for pesto and just about anything else, in a vigorous compact plant. Its densely mounding habit makes it great for containers or ornamental situations. In our trials with other Italian basils, Profumo continued to look fresh and happy when other varieties stressed out. Medium size leaves.
Approx. 100 seeds per packet
Grown in Potter Valley, California
Certified Organic by CCOF
Open-pollinated, non-GMO
1-3 business days
I'll do my best to meet these shipping estimates, but can't guarantee them. Actual delivery time will depend on the shipping method you choose.
Buyers are responsible for any customs and import taxes that may apply. I'm not responsible for delays due to customs.
Just contact me within: 14 days of delivery
Ship items back to me within: 30 days of delivery
But please contact me if you have any problems with your order.
Because of the nature of these items, unless they arrive damaged or defective, I can't accept returns for:
Buyers are responsible for return shipping costs. If the item is not returned in its original condition, the buyer is responsible for any loss in value.
I will only use your shipping and billing address, and contact information


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Hey there, time traveller!
This article was published 11/2/2013 (1653 days ago), so information in it may no longer be current.
Six unions representing 5,200 University of Manitoba employees will hold a rally at 11:30 a.m. Wednesday to protest the university's policies and spending decisions.
The unions allege that there is increased contracting out and spending reductions across campus, while alleging that the administration is increasing its own ranks.
The unions fear the effects of the plan now underway to reduce the 20 faculties to about 13 faculties by 2017. They will hold their information picket around the administration building.


text: Viewing Hard Times - 2 of 6 Hard Times - Episode 2 - Adam's Gay Roommate This is Episode Two of the new comedy web series HARD TIMES, created by New York... more »This is Episode Two of the new comedy web series HARD TIMES, created by New York actor/writers Michael Ferrell and Shawn Patrick Murphy. In Episode Two, Adam is distracted from the job quest because he's pretty damn certain his roommate has a thing for him. HARD TIMES is an "out of workplace comedy" about two friends in New York City who are unemployed and struggling to find work in these tough economic times. Through it all they deal with girlfriends, roommates, bad dates, and most of all, each other. Stay tuned for more episodes of HARD TIMES every Monday! http://livingboy.wordpress.com « less Michael Ferrell August 09, 2009 1.2k Views More Info Full Credits Michael Ferrell Uploader Additional Credits Created by: Michael Ferrell and Shawn Patrick MurphyWritten and Produced by: Michael FerrellEdited by: Kevin ChapadosAdam...Michael FerrellDerek..Shawn Patrick MurphyRyan...Andrew Boyd Stewart Stats & Data 146Funny31Die 1,205 Views August 09, 2009 Published Category Web Series Tags Hard Times episode 2 this is episode New Comedy web series New York Michael Ferrell Shawn Patrick Episode Two Patrick Murphy sitcom comedy funny Funny People economy unemployed cute sexy office Arrested Development conchords Up Next: Hard Times - Episode 3 - Derek's First Date AUTOPLAY Up Next In: 10 Hard Times - Episode 3 - Derek's First Date Hard Times - Episode 4 - Adam's Girlfriend Hard Times - Episode 5 - Tightly Wrapped Hard Times - Episode 6 - Derek Gets Evicted Follow Browse Related Comments Hard Times 6+ more View All ▶ 10+ more View All ▶ Michael Ferrell Vaguely Related Videos Vaguely Related Pics & Words Advertisement Tags: Hard Times episode 2 this is episode New Comedy web series Advertisement


text: No recent wiki edits to this page. Marcus Junius Brutus (85 - 42 BC) was a historical figure. He was a nephew of Cato the Younger, son of Servilia Caepionis and suspected biological son of her lover Julius Caesar. He is best known for assassinating Caesar in 44 BC. He then fought an extended civil war against Caesar's political heirs Mark Anthony and Octavian. He commited suicide after loosing said war.In the Asterix comics, Brutus is an adoptive son to Caesar and wants to succeed him by any means possible. He sought to assassinate his adoptive brother Caesarion, leading to Cleopatra entrusting her son to Asterix. Relentless, Brutus managed to burn Asterix's village to the ground and was only stopped by Caesar himself. So far Brutus has been the most effective enemy of the villagers.


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E L A R I A Model
Lee Tuckett PhotographyPhotographer Female Camberley–Frimley, England, United Kingdom
My Website: Lee Tuckett Photography
Mayhem # 2255394
About MeI have two photography business that sit side-by-side the longest established is the sports photography the I shoot under the company name of Photos at Work. This is mainly childrens sports activities.
The other business is Lee Tuckett Photography - I would class this as my more creative work and the one where I am looking to build my portfolio further and establish my "style"
I am looking forward to working together with models and MUA's to help develop my technical skills and my style of shooting.
Have you worked with Lee Tuckett Photography? Add Credits for Lee Tuckett Photography! >>
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text:
The Destruction Of Capitalism Is Well Underway. When Are We Going To Do Something About It?
Christiana Figueres, who heads up the U.N.'s Framework Convention on Climate Change, has said: "This is probably the most difficult task we have ever given ourselves, which is to intentionally transform the economic development model, for the first time in human history. "This is the first time in the history of mankind that we are setting ourselves the task of intentionally, within a defined period of time, to change the economic development model that has been reigning for the, at least, 150 years, since the industrial revolution." Hold that thought. Meanwhile, the big political story in Britain in the last week has been a new Cash for Access scandal which lead to the defenestration of two senior Parliamentarians: Labour's Jack Straw and the Conservative's Malcolm Rifkind. Both are former Foreign Secretaries. Both were caught by Channel 4's Dispatches program offering to use their positions as politicians to benefit a fictitious Chinese firm in exchange for at least £5,000 a day. And both will now be stepping down at the… Keep Reading


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Water and Well Depth
"What is well depth?"
Well depth is defined as the full depth from ground level to the solid rock at the bottom of your well shaft.
"What is the difference between the water table and static water level?"
Static water level or (simply) water level are synonymous phrases and define the depth or distance from ground level to the level of water within the well -- at RESTING STATE.
"Resting state" means you are not pumping and haven't pumped recently, and the well has filled back up to it's maximum level. If you have pumped, then the water level, of course, is changing as the well fills back up to the static level. (The speed at which it refills - e.g. three gallons per minute - is called your "Recovery Rate".)
Water Table is the level below which the pores in the soil and rock and saturated with water. The static water level in an individual well can be quite a lot higher or lower than the water table, depending on the shape of rock strata and their relative permeability.
"How do I determine the static water level?"
You can approximate the depth to groundwater from the well driller's drilling log when the well was initially drilled. If you don't have this information, you can contact a local well driller to have the water depth confirmed by sounding or other measurement technique.
NOTE: If you want to determine your static water level yourself, you'll need: a small steel weight, a 1 1/4" to 1 1/2" diameter bobber, 200 feet of a lightweight fishing line or kite string.


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I get a lot of support from my supervisors. They are just amazing.
The Department of Politics is a thriving space for research and public engagement on a range of political areas. We focus most of our research activity through our research centres: the Centre for Research on the European Matrix (CRonEM) and the Centre for International Intervention (Cii).
With colleagues working across political and international relations topics, and an open and collegiate environment, we encourage and support innovative thinking and activities, with postgraduate researchers playing an important role in this.
This includes opportunities for researcher training, discussion and presentation of work and regular external speakers, as well as participation in the events organised within the Faculty and University. Our doctoral programme promotes high-quality research in politics, international relations and policy studies.
At present we have about 15 doctoral students working on a wide range of issues.
We welcome applications from students who would like to conduct research (leading to an MPhil or PhD degree) in any of our areas of expertise.
However, we are also interested in hearing about other areas in which you would like to conduct research, if they are broadly in line with the School's areas of research.
Key research areas include:
Research students within the Department are well supported; in addition to regular supervision sessions with supervisors, all students are able to take advantage of training opportunities at University and Faculty level.
We also have a dedicated room for all research students with good ICT facilities.
The Department of Politics also offers Faculty-funded studentships.
Faculty studentships are available for top-quality students, covering tuition fees at the Home/EU rate and maintenance at current research-council rates for full-time or part-time study.
The Asako Okukubo Prize is awarded each year to a student who has completed a research degree programme within the Department of Politics and who has produced a doctoral thesis of 'excellence'.


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Free Stuff, Samples, Coupons, and Sweepstakes | Woman Freebies
January 24, 2015 | Birthday Freebies, Rewards
Yes you heard that right, FREE yogurt from Pinkberry! Simply click on the link below and learn how to join their exclusive loyalty program and you'll receive a free yogurt on your birthday. Plus, you'll receive other great offers all year long. What do you have to lose? Join now!
You work too hard for your money to throw it all away on full price when you don't have to!
© adjump 2011 All Rights Reserved No part of this website or any of its contents may be reproduced, copied, modified or adapted without adjump's prior written consent.


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Central Bank of St. Louis
O'Fallon, IL
About Us
Change Location
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McCall's 9053; ©1984; Brooke Shields - Misses' Jacket & Dress: Unlined, loose-fitting jacket has shoulder pads, patch pockets and full length sleeves. Buttons, snap fasteners or snap tape may be used for front closure. Straight, sleeveless T-shirt dress, in two lengths, has bound neck and armhole edges and left side closure with buttons, snap fasteners or snap tape. Jacket and dress: Topstitching.
Links to reviews/blog postsEdit


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Carhartt WA613
Carhartt Women's Floral Print Cotton Crew Sock
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This crew sock provides Carhartt quality in a feminine lightweight look. Soft, breathable cotton and cushioned sole provide all day comfort. Terry-to-top upper provides padded comfort for ankle and shin.• 53% Cotton, 35% Nylon, 10% Polyester, 2% Lycra® Spandex
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– One of the highest rated adventure games remastered for iPhone and iPad –
Oslo, Norway – November 27th, 2014 – Funcom today announced that the beloved and critically acclaimed adventure game The Longest Journey® is now available in the App Store for iPhone and iPad.
First released on Windows PC in 1999, The Longest Journey was met with rave reviews and is still considered one of the greatest adventure games ever made. At the time GameSpot proclaimed it to be 'one of the best adventure games in years', bestowing upon it a 'Game of the Year' award. IGN handed it an 'Editor's Choice' award, saying '...the game ranks up there as one of my favorite entertainment titles of all time, not just out of video games, but of all media.'
Spanning over 150 locations and more than 50 hours of gameplay, the game features a gripping storyline and a huge cast of fully-voiced characters. With the power to move between worlds like others move from waking to sleep, April Ryan must embark on the longest journey of her life; a journey not only across twin worlds, but also into her very own heart and soul. The iOS version of the game features new controls customized for mobile devices, a dynamic help system and a new intro and outro narrated by series creator Ragnar Tørnquist.
The Longest Journey is the first game in the critically acclaimed adventure saga, and this year Mr. Tørnquist and his team at Red Thread Games launched, under license from Funcom, Dreamfall Chapters®, an episode-based third entry into the beloved series. Tørnquist himself is excited to see Funcom bringing 'The Longest Journey' to mobile devices:
"There is no doubt The Longest Journey lends itself perfectly to mobile and tablet devices, it plays really well," says Ragnar Tørnquist. "This release will open up The Longest Journey universe to a whole new audience, but it's also a great way for veterans to experience the adventure again. It's a great springboard into Dreamfall® and 'Dreamfall Chapters!"
The Longest Journey: Remastered® is now available through the App Store worldwide.
ABOUT FUNCOM: Funcom is an independent developer and publisher of online games for PC and consoles. Funcom has provided outstanding entertainment since 1993 and continues to expand its track-record of more than twenty released games. Recent titles include 'The Secret World', 'Age of Conan: Hyborian Adventures', 'Anarchy Online' and 'Dreamfall: The Longest Journey', as well as 'LEGO Minifigures Online' which is currently in development. For corporate information please visiit www.funcom.com. For information about Funcom games visit www.playminifigures.com, www.anarchy-online.com, www.dreamfall.com, www.thesecretworld.com or www.ageofconan.com. Funcom is listed on the Oslo Stock Exchange under the ticker FUNCOM.


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I am having some scan errors and is was suggested i check my scan logs, one consistency through out all the logs is the TFTP server is not started....should i be concerned? is this something i need to add in? or is this just a routine check SW makes when starting a scan?
Jan 24, 2012 at 4:51 UTC
The TFTP server is used with network config backup. If this related to the WMI topic, it's not used with network discovery of Windows machines.
Hope this helps clarify the function :)
This topic was created during version 5.3.
The latest version is 7.5.00101.
6 Replies
Jan 24, 2012 at 2:34 UTC
While I don't have an actual answer for you.... if you tell me the path to those logs I CAN tell you whether I have the same/similar entries if you like. It might at least let you know if it is anything to be concerned about or possibly just functionality you don't utilize..... (let me know if you want me to check)
Jan 24, 2012 at 2:38 UTC
on your SW server
C:>Program files (mines was in X86)> Spiceworks> Logs> the specific logs i was looking at are the finder_cust#.log
Jan 24, 2012 at 2:51 UTC
Well I just had a look and do not have a log with that exact name... I checked both logs I DO have that begin with "finder" and one log had no entries matching ... the other had a single entry:
I[11:58:21.62 af706c] TFTP server not started
like that...... I do only have one of those entries in the entire log.... maybe it only happens during a restart of SW? Sorry ... I should mention that I JUST moved SW to a new server, and do not think it has scanned anything yet, which might account for the lack of those entries OR you are scanning something "custom" as per the name of the log file........ and we are not.
Sorry not very useful I know.....
Jan 24, 2012 at 2:58 UTC
oh i should have mentioned the # will be a number, these logs the finder_cust is a log for custom scan. but no that tells me that is probably just a standard check SW does and is not important...i am assuming.......
Jan 24, 2012 at 4:51 UTC
The TFTP server is used with network config backup. If this related to the WMI topic, it's not used with network discovery of Windows machines.
Hope this helps clarify the function :)
Nov 6, 2012 at 12:42 UTC
1st Post
It does help clarify the function, but doesn't tell us why it's showing up in the logs.
For example, I'm trying to set up a new Spiceworks install specifically for config backups (that's how I'm selling it to management, anyway). I can't for the life of me figure out why it won't back up the Cisco 2950 switch I've added. Yes it has the correct SSH credentials, yes SNMP is turned on and the device is identified, and yes I've given it the enable secret.
Understanding how to start the TFTP server or why it isn't starting is just as important as understanding its function. Can someone please answer why it's showing up as not-running in the logs?
This discussion has been inactive for over a year.
You may get a better answer to your question by starting a new discussion.


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How to Get Insurance for Apartment Building Insurance?
Different types of insurance are required for different types of child care businesses. You should protect that investment and yourself by understanding the insurance available to you and deciding what to purchase. As a Electrician Insurance Chicago parents trust you to protect and care for their most valuable assets. Protect yourself and your business with Contractors Insurance through the Progressive Commercial Advantage program today. Choose the Best Term Insurance Plan, Travelers specializes in fulfilling the insurance and risk management needs. When you choose an insurance company and manufacturing facilities in the business and employ a team of highly skilled engineers. We have experts specially trained to help contractors and small business owners understand their options.
In finance, a bond is an instrument of indebtedness of the bond issuer to the holders. The specific independent contractor's liability insurance coverage you need will be unique to your business. You can count on our team of professionals to provide cost-effective. Insurance covers many types of equipment. This form of insurance provides important mechanical breakdown coverage generally not available under any other insurance policy. When you take insurance covers the costly physical and financial damages. A covered cause of loss is a sudden and accidental breakdown of the insured's boilerandmachinery equipment or any part of the equipment described. Boiler & Machinery insurance covers direct damage to covered property when caused by a covered cause of loss. You can contact us and visit our site Cacciatoreinsurance.com at 312-264-6055.


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Lutheran Homes Society | Nursing Home
Talk to a Family Advisor:
Reviews of Lutheran Homes Society | Nursing Home
Caring86799350 November 06, 2014
I am a friend or relative of a resident
Lutheran Living really encouraged the clients to get out of bed and get out of their rooms. They have several sitting areas, and the rooms were big and clean. The staff was wonderful. My dad was there for skilled nursing for a bit, and they were awesome and were very knowledgeable. In terms of letting me know what's going on, they were right on. They had to change my dad's medicine, and they always called me before they give anything to let me know what was going on. I think they need to clean the rooms a little more often -- not that it was dirty or anything by any means -- but sometimes they have to go in and pick up trash and stuff off my dad's floor. The staff was great. I think they need to work on trying to get the clients out to do more activities. They have more activities not just in the evening but throughout the day, and they really tried to encouraged them.
Write a Review
About Lutheran Homes Society
Lutheran Homes Society is a nursing home in Muscatine, IA that provides patients with skilled nursing care as well as private or shared accommodations. Contact Lutheran Homes Society for more details on housing, services, and rates.
Features of Lutheran Homes Society
Medicare (ratings last updated: 06/16/17)
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- Medicare Provider Number: 165432
- Ownership Type: Non Profit Church Related
- Date Certified: 05/01/2017
- Resident Capacity: 155
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text: Share: 30 Desserts Made in a 13x9 Pan Crowd-sized chocolate sheet cakes, apple crisp, strawberry pretzel desserts, peanut butter bars and more recipes are perfect for potlucks when made in a 13x9 pan. 1 - 31 View all thumbnails One-Bowl Chocolate Cake This cake mixes up quickly and bakes while we enjoy our dinner. My son, David, loves to help decorate it. —Coleen Martin, Brookfield, Wisconsin Get Recipe Pineapple Orange Cake This is one of my favorite cakes. It's moist and light yet so satisfying. I've been adapting it for years and now it's almost guilt-free. —Pam Sjolund, Columbia, South Carolina Get Recipe Chocolate Mint Brownies One of the best things about this recipe is that the brownies get moister if you leave them in the refrigerator for a day or two. The problem at our house is no one can leave them alone for that long! —Helen Baines, Elkton, Maryland Get Recipe Contest-Winning Caramel Apple Crisp When my kids and I make apple crisp, we use all sorts of apples to boost the flavor and texture. Add melted caramels, and you've got something scrumptious. —Michelle Brooks, Clarkston, MI Get Recipe Peanut Butter Custard Blast "Ooey, gooey, great!" is how friends and family describe this chocolate-peanut butter dessert. I appreciate the make-ahead convenience. —Marilee Evenson, Wisconsin Rapids, Wisconsin Get Recipe Pretzel Dessert Save both time and money with a big batch of this sweet and salty, creamy and crunchy treat. Any dessert that is left over is super the next day, too. —Rita Winterberger, Huson, Montana Get Recipe Tiramisu Cheesecake Dessert Tiramisu didn't do it for me until I tried this recipe, with its luscious layers of cheesecake and coffee. It's one of my favorite desserts to make this time of year. —Christie Nelson, Taylorville, Illinois Get Recipe CokeCola Cake We live in Coca-Cola country, where everyone loves a chocolatey, moist sheet cake made with the iconic soft drink. Our rich version does the tradition proud. —Heidi Jobe, Carrollton, Georgia Get Recipe Deep-Dish Apple Pie This recipe is a winner! The crust is so flaky and the filling is sure to please everyone. —Salem Cross Inn, West Brookfield, Massachusetts Get Recipe Blueberry Angel Dessert Make the most of angel food cake, pie filling and whipped topping by creating this light impressive dessert that doesn't keep you in the kitchen for hours. It's the perfect way to end a summer meal. —Carol Johnson, Tyler, Texas Get Recipe Peanut Butter Cereal Treats Kids will love these colorful, crunchy bars. They're a fun twist on the traditional marshmallow crispy treats…and because they're so easy, older kids could whip up a batch on their own! —Christie Porter, Shipshewana, Indiana Get Recipe Caramel Pecan Ice Cream Dessert My mother passed this old-time recipe on to me because she knew I'd want to make it. I love desserts—especially this one! —Mary Wright, Morriston, Ontario Get Recipe Strawberry Pretzel Dessert Need to bring a dish to pass this weekend? This make-ahead layered salad will disappear quickly at any potluck. —Aldene Belch, Flint, Michigan Get Recipe Apple Kuchen Bars This recipe is about family, comfort and simplicity. My mom made this delicious sweet treat many a winters night and served it up warm with some of her famous homemade ice cream. I like to make a double batch and pass on the love! —Elizabeth Monfort, Celina, Ohio Get Recipe Chocolate Peanut Butter Crunch Bars My twist on rice crispy bars includes crunchy crushed pretzels. Then I top them with a creamy peanut butter coating and rich chocolate topping. Garnished with peanuts and even more pretzels, I don't think I'd ever go back to plain old bars again. —Sherri Melotik, Oak Creek, Wisconsin Get Recipe P.S. I Love You Cake Growing up, there was always some scrumptious treat to eat at our house. The name my mom chose for this cake has a double meaning: P.S. for the type of cake (poppy seed) and for the love note to her family. —Sue Groetsch, La Crosse, Wisconsin Get Recipe Chocolaty S'mores Bars One night, my husband had some friends over to play poker and he requested these s'mores bars. They polished off the pan and asked for more! I shared the recipe, and now their families make them, too. —Rebecca Shipp, Beebe, Arkansas Get Recipe Rhubarb Mandarin Crisp An attractive dessert, this crisp is also a popular breakfast dish at our house, served with a glass of milk rather than topped with ice cream. Because it calls for lots of rhubarb, it's a great use for the bounty you harvest. —Rachael Vandendool, Barry's Bay, Ontario Get Recipe Chocolate Delight Dessert My three children loved this dessert so much that they begged me to get the recipe. It's so easy to make and tastes so good. And making it ahead of time frees your hands and your time for other to-do's! —Ruth Dyck, Forest, Ontario Get Recipe Spiced Pumpkin Tiramisu I transformed tiramisu from coffee to pumpkin-flavored for a special holiday with my brother and parents. A new Christmas tradition was born! —Heather Clary, Downingtown, Pennsylvania Get Recipe Chocolate & Peanut Butter Crispy Bars To make a dairy-free dessert, I created chocolate peanutty bars. My kids and their friends gobble them up. I talk about it on my blog, joyfulscribblings.com. —Dawn Pasco, Overland Park, Kansas Get Recipe Raspberry Custard Kuchen Back where I grew up in Wisconsin, people have been baking this German treat for generations. We love it for breakfast or as a special dessert. It's no fuss to fix and impressive to serve. —Virginia Arndt, Sequim, Washington Get Recipe Cinnamon Nut Bars Classic bar meets good-for-you ingredients in this updated recipe. If you have the patience, after the bars are cool, store them in a tin for a day to allow the flavors to meld...I think they taste even better the next day.— Heidi Lindsey, Prairie du Sac, Wisconsin Get Recipe Cranberry Pineapple Upside-Down Cake Both kids and grown-ups like this gorgeous dessert. It'll keep a few days and is actually better the second day, so you can make it a day ahead. —Sherry Conley, Noel Hants County, Nova Scotia Get Recipe Double Nut Baklava It may take some time to make this rich, buttery treat, but it's well worth the effort! The blend of coconut, pecans and macadamia nuts is irresistible. —Kari Caven, Coeur d'Alene, Idaho Get Recipe Malted Milk Cake Bake this cake in a 13x9 pan or as cupcakes in fun paper liners. I am a sweet and salty addict, so I sprinkle popcorn on top. —Susan Scarborough, Fernandina Beach, FL Get Recipe Cranberry-Orange Bars My mother has had this recipe for years. I love it! These bars make great snacks, but can also be served for dessert. —Margaret Adelman, Bellingham, Minnesota Get Recipe Caramel-Mocha Ice Cream Dessert You can use any flavor of ice cream in this frosty dessert. Chocolate and vanilla would be delicious substitutes for coffee and dulce de leche.—Scarlett Elrod, Newnan, Georgia Get Recipe Apple Cranberry Slab Pie My husband loves pie, so I made one with apples, raspberries and cranberries. It's so good, I bend the rules and let the grandkids have it for breakfast. —Brenda Smith, Curran, Michigan Get Recipe Fudgy S'mores Brownies I combined the perfect, simple summer snack with my favorite brownie recipe to get a treat that's sure to wow at your next big party. —Judy Cunningham, Max, North Dakota Get Recipe More Dessert Recipes Top 10 Lemon Desserts 22 Easy Cheesecake Recipes Grandma's Best Desserts ‹ › Back to slideshow One-Bowl Chocolate Cake Pineapple Orange Cake Chocolate Mint Brownies Contest-Winning Caramel Apple Crisp Peanut Butter Custard Blast Pretzel Dessert Tiramisu Cheesecake Dessert CokeCola Cake Deep-Dish Apple Pie Blueberry Angel Dessert Peanut Butter Cereal Treats Caramel Pecan Ice Cream Dessert Strawberry Pretzel Dessert Apple Kuchen Bars Chocolate Peanut Butter Crunch Bars P.S. I Love You Cake Chocolaty S'mores Bars Rhubarb Mandarin Crisp Chocolate Delight Dessert Spiced Pumpkin Tiramisu Chocolate & Peanut Butter Crispy Bars Raspberry Custard Kuchen Cinnamon Nut Bars Cranberry Pineapple Upside-Down Cake Double Nut Baklava Malted Milk Cake Cranberry-Orange Bars Caramel-Mocha Ice Cream Dessert Apple Cranberry Slab Pie Fudgy S'mores Brownies More Dessert Recipes Popular Collections Grilling Collections Farmers Market Recipes Quick & Easy Recipes Healthy Recipes Email a Friend Send a link to this slideshow to your friends, along with a personal message. From: To: Use commas(,) to separate up to 5 emails. We will not maintain any record of these emails. Your Name: Your Message: Send me a copy: Send Cancel Please wait... OK


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Dallas PD to Give Girl Back $2,000 She Found ... If Nobody Comes Forward In Next 120 Days
It's been more than three months since 15-year-old Ashley Donaldson found $2,000 outside a North Dallas strip mall and returned it to a nearby Chase bank, thinking someone there could find the owner. But city officials tell Unfair Park the bank didn't turn over the dough to the Dallas Police Department till April 13 -- and, as you're well aware by now, the city intended on keeping that money, based on the application of a state law dealing with found money. City Manager Mary Suhm and Mayor-For-Now Dwaine Caraway told Unfair Park earlier today they'd look into it.
But a few minutes ago, this arrived from Dallas PD HQ:
Dallas Police Chief Intervenes in Found $2000
Dallas Police Chief David O. Brown has directed that the department follow a provision in state law that allows for public notice to be given after thirty days of someone finding money and turning it into the Dallas Police Department. Once public notice has occurred, a ninety-day waiting period follows. If a claimant comes forward, a hearing is held within the Police Department. If no rightful owner comes forward during this 120-day period, then Chief Brown will return the money to the finder, Ms. Ashley [Donaldson].
Suhm then forward to Unfair Park the citation mentioned in the chief's press release: Texas Code of Criminal Procedure, Article 18.17, which deals with the "Disposition Of Abandoned Or Unclaimed Property."
Update at 6:15 p.m.: Mary Suhm just sent a memo to the mayor and council explaining what happened -- and what's next. She says some organizations have approached the city, saying they want to raise the $2,000 on Ashley's behalf. The city manager says that if the city winds up returning the $2,000 to the girl who found it, "the organizations will then be reimbursed.") Her memo follows on the other side. Jump, but be sure to keep your wallet in your front pocket.
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Although the staff we dealt with were all friendly the overall feel of the place was old, tired and not as clean as it could have been
Refresh Inn & Suites
Getting you more information on this room
Getting you more information on this room
"Ok for a one nighter extended stay maybe not. Traffic out front not an issue lighting good at nite lots of..."
"Don't stay in room 101, it is right across from the housekeepers storage room & is next to the door..."
"I don't think there is such a thing as a good room in this hotel. Noisy. Dirty."


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What is JotForm?
JotForm is a free online form builder which helps you create online forms without writing a single line of code. No sign-up required.
At JotForm, we want to make sure that you're getting the online form builder help that you need. Our friendly customer support team is available 24/7.
We believe that if one user has a question, there could be more users who may have the same question. This is why many of our support forum threads are public and available to be searched and viewed. If you'd like help immediately, feel free to search for a similar question, or submit your question or concern.
Unable to clone form even if the privacy setting allows form cloning.Asked by raypryor3 on January 23, 2015 at 02:15 AM
Hi, in Account > Settings > Privacy I have the box unchecked which should allow my forms to be cloned but when I try to "Import from a webpage" and enter a working form URL, Jotform gives me the error: "No form found on the page. Please check the source code you provided".
I turn this setting off and on from time to time but the privacy seems to be stuck on "off"
Any ideas? Thanks in advance.
JotForm Support
Hello raypryor3,
I'm sorry for the trouble caused to you.
I did check your account privacy setting and the form cloning seems to be allowed. I did try to clone one of your form and I was able to do that successfully in my support as well as free account. Please check the screenshot below:
Let me report this issue to our back end team. We will get back to you as soon as we have any update form them.
In which account you are trying to clone your form? Please try to sign out and then sign in again before cloning form in destination account and see if that helps you.
Thank you!
Hi Ashwin, thanks for the reply. I see the screenshot but the strange this that I cannot clone this form. I just created a new free account and it doesn't work there either.
- The accounts you tried this from, where they new?
- I'm trying to import this into an account named kellyrobertson
Ok, so after looking at the other threads on this, it looks like this is an issue that support is not able to reproduce, but many users are obviously having the same problem.
- Can you someone in support try and reproduce this from a domain outside of jotform support? Maybe your home connection or your phone? I tried from my laptop and phone with no luck.
- BTW, the clone function was working perfectly before a couple days ago. Did something change on the backend over the last couple of days?
- I am in the US
Thanks in advance for your help
This may have to do with the domains.
When I click the Embed form wizard, I get a form URL in this format:
- http://form.jotform.us/form/#######
but in other support posts I've seen the URL in the format of:
- http://www.jotform.us/form/####### ( note the www )
and one has even had the format of:
- http://www.jotform.me/form/ ( note the .me )
Could this be the issue???
It seems like the form URL works when you visit it directly, but it won't allow cloning.
Having same problem. Digging further I see error 400 being returned from
and further checking shows:
{"error":"Unauthorized request. You do not have access to this form","success":false,"duration":"0.029"}
The form I'm trying to clone is:
Hi raypryor3,
You should be able to clone the form using any of those URLs, as long as the user allows for the form to be cloned.
This has been escalated to our second level support, it has also been given a priority of Very Important. Any update on this issue will be posted on this thread.
I have moved your post to a new thread: http://www.jotform.com/answers/502390
It will be addressed there.
Thank you.
JotForm Developer
The problem about clone form feature is fixed. I've tested it with a non-support account and able to clone existing forms.
We are truly sorry for any inconveniences caused.


text: I need some help with my site link, I had to suddenly change my domain link and just need to know what links I need to update. \n\nI updated my hosting main domain link, my xen license, my main board link via the ACP options and any requiring addons. \n\nI noticed my skin images aren't loading right and wondering what I need to change there?


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Overview Edit
U.S. government acquisition management is carried out by the Office of Acquisition Policy (OAP), within the GSA's Office of Government-wide Policy, which is under the guidance of the Chief Acquisition Officer and the Senior Procurement Executive. The office's mission is to strengthen GSA's acquisition policy and operations and to provide federal agency customers with an acquisition policy that enhances their missions.
OAP supports the GSA acquisition workforce through attention to their training, certification, and warrant needs. OAP also provides timely acquisition regulation, policy, and reporting for internal and external stakeholders, oversees acquisition integrity functions for GSA, including suspension and debarment of contractors or participants in non-procurement programs, agency level acquisition protests, agency task/delivery order ombudsman functions, internal procurement management reviews, and agency competition advocate functions.


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Awards & Recognition
MassCUE will be honoring the recipients of the 2016 Administrator Award and Pathfinder Award at the 2016 Fall Conference. Learn more about these awards and past recipients from the Awards & Recognition Committee.
Recent Recognition
Stay tuned. More exciting information acknowledging our MassCUE members will be updated here soon.Print this page


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found a new home!
Plenty of my friends are looking
for one too. Find a pet to adopt.
I am already neutered, housetrained, purebred, up to date with shots, not good with kids, good with dogs, and not good with cats.
He needs to learn some manners and gain a couple pounds, but he has great potential!
Please submit our adoption application online www.texasbullterrier.org/rescue_information.html.
Brock, a Houston Bull Terrier dog was adopted! Here's how you can benefit by looking at adoption as an option to buying a Bull Terrier for sale in Houston, or seeking a Bull Terrier dog from a breeder in Houston.


text:
Display posts with format
I use wp_query to query recent posts and display them on the home page.
Each post has format, like Enter, underline. But when it displays on the homepage, it is a just a long line of strings.
To see what I mean you can compare:
My site URL : http://essentialtutorial.com/
A blog post : http://essentialtutorial.com/133/
How do I display the post with format (not just line of strings) on the home page? Thanks
- The topic 'Display posts with format' is closed to new replies.


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MANATEE COUNTY, Fla. -- When Marsha Panuce lost her beloved husband Don, she became a woman on a mission to help pets who have lost their owners. And for that, she is our Amazing Suncoast Woman.
Marsha and Don never had children, but they had dogs that they loved dearly. So after Don's death, Marsha set out to create a place for dogs who outlived their owners. And Monday, that place took the next step to becoming a reality.
It'll be called Donte's Den after their beloved dog Donte that died before his time. It will be a state of the art forever home for dogs that outlive their owners.
As the shovels dug in at Monday's groundbreaking, Panuce's dream was materializing.
Marsha was born in Chicago, an only child who loved animals and had a great musical talent. "My mother was a concert pianist. There was always music; she sat me down at four and she noticed there was natural talent to get me to American Conservatory of Music."
She was soon performing around the world. In Milan, Italy, the beautiful fashions inspired her. "I embarked on my 2nd career and I developed a fashion business."
She moved in the world of the rich and famous. Then love struck. "I met a Chicago boy in Italy; he was developing his business, which was an electrical manufacturing business."
They joined their lives and their businesses and moved to Sarasota. Marsha joined ABC 7, focusing on fashion, did a pet show on SNN, then returned to ABC 7 for her show that's getting rave reviews, Animal Outakes.
Marsha and Don didn't have children; they showered their love on their dogs. But they had one great worry. "We didn't have a family, we were career people, we were business people, we traveled. What would happen to our dogs if we weren't around to take care of them?"
They dreamed of a place that would care for dogs when their owners no longer could.
And when Don passed away from pancreatic cancer, Marsha set out to make their dream come true in his honor. "For us it is fulfilling the promise the owners have made when you take that dog, you make a commitment. That commitment is a life-long commitment for a dog. Unfortunately, sometimes we can't see it through, but Donte's Den can be there."
And her life lesson? You need to have a dream, but that's just the beginning. "Then you set the goal and you work hard. I never found an easy way around anything; I had to work hard. But if you dream and set that goal, reality will come, and then the joy."
Marsha Panuce is truly an amazing woman who thinks of everything. The groundbreaking included gold pooper scoopers. Now she's putting her heart and soul into Donte's Den. Truly a community of joyful dogs.


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|"Patrick Hunt (Commented) (JIRA)" <j...@apache.org>
|[jira] [Commented] (MAPREDUCE-4140) mapreduce classes incorrectly importing "clover.org.apache.*" classes
|Thu, 12 Apr 2012 00:35:13 GMT
[ https://issues.apache.org/jira/browse/MAPREDUCE-4140?page=com.atlassian.jira.plugin.system.issuetabpanels:comment-tabpanel&focusedCommentId=13252096#comment-13252096 ] Patrick Hunt commented on MAPREDUCE-4140: ----------------------------------------- @eli I tried fixing that as well, but at first look it seems that clover is not working on trunk in general (conflicting with proto generation changes). I will enter a jira for that was well. > mapreduce classes incorrectly importing "clover.org.apache.*" classes > --------------------------------------------------------------------- > > Key: MAPREDUCE-4140 > URL: https://issues.apache.org/jira/browse/MAPREDUCE-4140 > Project: Hadoop Map/Reduce > Issue Type: Bug > Components: client, mrv2 > Reporter: Patrick Hunt > Assignee: Patrick Hunt > Attachments: MAPREDUCE-4140.patch > > > A number of classes in mapreduce are importing clover.org.apache.* classes > e.g. hadoop-mapreduce-project/hadoop-mapreduce-client/hadoop-mapreduce-client-hs/src/main/java/org/apache/hadoop/mapreduce/v2/hs/PartialJob.java -- This message is automatically generated by JIRA. If you think it was sent incorrectly, please contact your JIRA administrators: https://issues.apache.org/jira/secure/ContactAdministrators!default.jspa For more information on JIRA, see: http://www.atlassian.com/software/jira
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Hi All,
I have a quick question. I am trying to setup Dreamweaver MX to test my asp.net pages and am having some trouble. I have ran through a few tutorials I found online but still cannot get it going.
If someone knows of a good tutorial to use or could possible explain the steps to get it going I would greatly appreciate it.
I have IIS installed running Windows XP Pro and Dreamweaver MX. I have setup my testing site in Dreamweaver and have it pointing to the wwwroot folder.
Any suggestions?
Thank you,
2 Replies
Apr 28, 2010 at 8:54 UTC
I don't know much bout it never tried it myself but here is a link where they talk about it. GOOGLE works very well usally
Remember don't be alone the telephone was only invented once!
May 13, 2010 at 11:29 UTC
Please forgive my bluntness but why not try Visual Studio 2010 Web Developer Express? All in one suite, very handy.
If not, trying setting the production (not testing) folder to C:\inetpub\wwwroot, and then trying.
This discussion has been inactive for over a year.
You may get a better answer to your question by starting a new discussion.


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How could it be that she's already 14 months old? I keep looking at her in awe. How fraglie and tiny she was.We are SO,SO blessed.
I remember each nervous night having to leave and go home w/out her. How I would be calling every 2-3 hours to speak to someone so they could give me an update even though they would say she was fine I just needed to hear it.
Those moments being able to hold her even if she was all hooked up,then slowly seeing the wires become none. To finally being able to bring her home and see her grow along w/her sibling. God is SO Good. We are so blessed.
Grow Isy Grow. On to many more adventures my sweet girl. We love you so much.
Just Like That
Sunday, August 31, 2014
Posted by Ellie Augustin at Sunday, August 31, 2014
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- Capetonian
- noun see Cape Town
New Collegiate Dictionary. 2001.
New Collegiate Dictionary. 2001.
capetonian — cape·to·ni·an … English syllables
capetonian — kāpˈtōnēən noun ( s) Usage: capitalized Etymology: irregular (influence of such words as Newtonian, Bostonian) from Cape Town, Union of So. Africa + English ian : a native or inhabitant of Cape Town, Union of So. Africa … Useful english dictionary
Capetonian Hotel Cape Town (Cape Town) — Capetonian Hotel Cape Town country: South Africa, city: Cape Town (City Centre) Capetonian Hotel Cape Town The Captonian Hotel is conveniently situated in the centre of Cape Town, within walking distance of all shops and offices and is also close … International hotels
Capetonian Hotel — (Кейптаун,Южно Африканская Республика) Категория отеля: 4 звездочный отель Адрес: Pier Square … Каталог отелей
Cape Town — Capetonian /kayp toh nee euhn/, n. a seaport in and the legislative capital of the Republic of South Africa, in the SW part: also capital of Cape of Good Hope province. 1,108,000. Also, Capetown. Afrikaans, Kaapstad. * * * Afrikaans Kaapstad City … Universalium
John-Laffnie de Jager — (17 March 1973) is a former tour professional tennis player. A doubles specialist, de Jager reached the semi finals for three different grand slam tournaments three times in three different years partnering three different fellow South African… … Wikipedia
Cape Town — geographical name city & port, legislative capital of Republic of South Africa on Table Bay; formerly capital of Cape of Good Hope population 776,617 • Capetonian noun … New Collegiate Dictionary
Cape Town — For other uses, see Cape Town (disambiguation). Cape Town Kaapstad iKapa City … Wikipedia
Memel, Free State — Memel Country South Africa Province Free State Population (2001) Total 469 … Wikipedia
District Six, Cape Town — District Six (Afrikaans Distrik Ses ) is the name of a former inner city residential area in Cape Town, South Africa. It is best known for the forced removal of over 60 000 of its inhabitants during the 1970s by the apartheid regime. Creation and … Wikipedia


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Complaint against Hazare, 8 others for tricolour insult
A complaint was today filed in a court in Bihar's Muzaffarpur district against social activist Anna Hazare and eight others for insulting the national flag.
The complainant alleged that the tricolour hoisting at the commercial programme amounted to its dishonour as it was not done as per the guidelines of the National Honour Act, 1971 and the National Honour (Amendment) Act, 2005.
Ojha prayed to the court that the accused persons be tried for breach of the Honour Act and sections 2 and 5 of the Honour (Amendment) Act.
The CJM transferred the complaint case to First class judicial magistrate Mithilesh Kumar and posted the matter for hearing on September 12.
Besides Hazare, civil society member Arvind Kejriwal, singer Kailash Kher, Javed Ali, Adnan Sami and Alka Yagnik have been named in the case.


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A guy I've been chatting with online for several months now was meant to call me on Tues to talk about him travelling to my country to give us a chance at a relationship (so we are LD). We had met in person as friends a few years ago when I was in Latin America and recently reconnected. We normally chat each day and HE told me Mon night that he wanted to speak about it more seriously the next day, in terms of making a plan. Well I was left waiting for the call, and continued to see over the last 3 days he never got the 2nd tick on Whatsapp. However, when I went to check his FB Messenger status I could see he had been active several times during these days. Today he finally sent a message via Messenger saying "Vanesa, my whatsapp is disabled. So sorry I haven't been able to communicate with you :/"
I left it at seen and did not respond.
Now I just find it strange that he has been MIA since HE mentioned talking about us more seriously - has he changed his mind and If so, why not just say so? He has never been away from chat this long before and we've spoken on the phone before.
Also, why did it take 3 days to send a quick text on Messenger if he had been active few days earlier.
How can Whatsapp be disabled yet data works on Msngr?
Am I being made a fool? 😔
Most Helpful Girl
You probably need to give him the benefit of the doubt, there were instances that my WhatsApp has been disabled for an overdue update but I never got to it because of poor reception.
BUT with that being said, he probably should have reached out to you prior, if he knew that his WA wasn't working properly. Best to just ask him where you stand. It is a bit of a red flag but again, nothing worth overthinking until you speak to him about it and clear things out.11|00|0
Hi Karen. Thanks for the opinion.
It's true, my sister wouldn't receive messages via WA for some days due to an update issue. I would understand that except, as I mentioned, he didn't reach out earlier. I guess the final question in mind for me is why isn't he eager to fix the issue (if that is the problem) to get back in contact asap. The (low) level of interest has me questioning myself.
- Show AllShow Less
I decided to reply and said that it seemed as though he had changed his mind about the situation. He told me that wasn't it. So I asked him what had happened to his WA & he said the screen on his phone was damaged and he has sent it to be repaired, that he was using a temporary phone. He insisted that that was the reason and that he had been dying to hear from me, that he should've let me know beforehand (though I did not mention I had seen his online Messenger status). I want to believe him, but I just find it strange that it happened when it did and that he didn't let me know exactly what happened to his phone. I mean, if he can use fb then why not WA on this "other" phone. 😔
Honestly if he could check his messenger, I don't see the reason why he couldn't check his WA either.
If he was just waiting for you to approach him- why couldn't he have let you know and explained it then if it was "broken"


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An earring is a jewel joined to the ear through a piercing in the ear cartilage or some other outside part of the ear. Earrings are worn by both genders Mens earrings and women earrings, albeit more basic in ladies, and have been utilized by various developments at various circumstances.
Penetrating spots other than the ear cartilage incorporate the tower, the drink, and the helix. The straightforward term "ear penetrating" for the most part alludes to an ear cartilage puncturing, while the highest point of the external ear piercings is regularly alluded to as "ligament piercings." Cartilage piercings are more unpredictable than ear piercings and take more time to mend.
Earrings segments can be produced using any number of materials, including metal, plastic, glass, valuable stones, pearl, wood, bone, and different materials. Plans run from little circles and studs to vast plates and dangling things. The size is at last constrained by the physical limit of the ear cartilage to hold the earring without tearing. Be that as it may, substantial earrings worn for drawn out stretches of time can prompt to extend the rear projection penetrating.
In India, every single Indian young lady and some young men get their ears pierced in religious service known as Kharnavedha before they are around five years. Infants can get their ears pierced when a few days after birth.
Comparative traditions are polished in other Asian nations like Nepal, Sri Lanka, and Laos, albeit generally, most men hope to have pierced ears until they achieved adulthood.
Types of earrings
Stud earrings
The fundamental element of the earrings is the presence of drifting on the ear or ear cartilage without an association point (front) unmistakable. Studs are constantly built on the end of a stick, which enters straight through the ear or ear cartilage. The post is held set up by a removable back brake or grasp. A slant demonstrates a gemstone or other adornment mounted in a limited shaft goes through a gap in the ear or ear cartilage and held set up by a gadget on the opposite side. Studs ordinarily come as precious stone solitaire. Here and there, the plant is built with the end goal that the post is strong, permitting a screw back to hold the incline. This is helpful for keeping the loss of costly earrings containing valuable stones or valuable metals.
Hoop earrings
Circle earrings are roundabout or half circle outline, and fundamentally the same as a ring. Pierced ears circle ordinarily come as a hover of metal that can be opened to experience ear penetrating. They are frequently developed of metal tubing, with a thin wire that enters the ear. The empty tube is appended for all time on the front of the ear and slips into the tube at the back. The whole gadget is held together by strain between the wire and tube. Other circle outlines don't finish the circle, yet enter through the ear in a post, utilizing similar procedures that apply to union earrings. A variety is the consistent loop earring. In this outline, the slant is developed of a persistent bit of strong metal, which infiltrates through the ear and can be turned right around 360 degrees. One end is for all time appended to a little bit of metal tube or empty metal line. The flip side is embedded into the tube or link and is held in position by strain. An uncommon kind of incline is pending a roundabout wire ordinarily in gold, with a breadth of around one centimeter. Joins with pivots, which are regular in Britain in the 1970s incorporate two strings crescent gold associated by a little pivot toward one side and associated with a little pin to each other to frame a consistent ring that the locking system it is successfully imperceptible to the bare eye. As a result of their little size makes them simple and agreeable, and on the grounds that they are generally unadorned, it is said that the sleepers, as they were intended to be worn during the evening to keep a nearby ear pierced, and were regularly the decision for the principal set of exceptional instantly in the wake of piercing of the ear in the prior decades ear penetrating weapons utilized nails have turned out to be typical, however frequently a strategy for decision in themselves due to their appealing effortlessness and on the grounds that inconspicuously encourage the way that the ear is pierced.
Drop earrings
A joined earring to ear cartilage and a gem or an adornment holding tight a chain, a ring or something like that. The length of these examples for the short and long Batty. These earrings are at times called earrings, dangling earrings or dangling earrings. Additionally included ceiling fixture earrings, which ramify in the complex multi-level hanging.
Dangle earrings
Dangling earrings are intended to spill out of the base of the ears and are accessible in different lengths of maybe a couple centimeters, all brushing shoulders. Typically they are connected with the ear by utilizing fine child, going through the ear cartilage and interface with themselves in a little snare on the back. An option is a French snare, it just hangs without shutting the ear flap, albeit little plastic tanks is in some cases utilized at the closures of French snares. Once in a while, dangly earrings utilize configuration work stick.
Barbell earrings
Do Bar is named for its likeness to a bar, generally, it comes as a metal bar with a circle at every end. One of these circles is settled set up, while the other can be isolated to permit dumbbell to be embedded into a borehole. There is a few minor departure from this fundamental outline, incorporating the weights with bands or edges on the bar of the incline.
Huggy earrings
Huggy are a famous style of earring where the setting really grasps his ear cartilage. These can come in various shapes and sizes, from the hearts of the rectangles. Numerous custom diamond setters make huggy earrings due to the numerous assortments of settings that can be utilized to make a decent layout for their specialty. Most circumstances, stones are channel set ears Huggy earrings.
Slave earrings
The slant slave earring is additionally called a "Bajoran" which turned out to be extremely prevalent after it showed up on Star Trek.
Ear Thread
Then again drive soil, ear chain Threaded, a chain that is sufficiently thin to slip into the ear opening, and back, hangs. Once in a while, people include globules or different materials in the chain so that the chain pendant with dabs beneath the ear.
Ear Spikes
One kind of plastic sticks 1mm in measurement and 1.5 cm long entering the ear penetrating. Slamming not on account of it is somewhat bigger than the drag. It is exceptionally prominent among teenagers and tweens in Hong Kong, as most schools don't permit pending.


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Bishan Villas
Call us 1800-300-2400-1 (Toll Free) and Get additional Discount upto 50% for this Hotel.
Near Gujrat Circuit House, Pilgrim Road. Delwara Road, , Delwara Road, MOUNT ABU, Rajasthan, India, Pin-307501
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About Bishan Villas
Bishan Villas is located near Gujrat Circuit House and just 50 meters from Dilwara Bus Stand in Mount Abu. It offers parking facility for all the guests. This Mount Abu home stay accommodates 6 well-furnished rooms equipped with a wardrobe and an attached bathroom with hot and cold water facility.
No of floors: 1 | No of rooms: 6
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Hotel Information and Amenities
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text: A korintol was a wind and string instrument with four hundred seventy keys, played by the Kirithons. Darien was a master of the korintol. He had been taken to Kandasi by the Panjistri to practice and refine his art. (PROSE: Timewyrm: Apocalypse) Retrieved from "http://tardis.wikia.com/wiki/Korintol?oldid=1851886" Ad blocker interference detected! Wikia is a free-to-use site that makes money from advertising. We have a modified experience for viewers using ad blockers Wikia is not accessible if you've made further modifications. Remove the custom ad blocker rule(s) and the page will load as expected. Categories: Musical instruments + cat Cancel Save


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Virginia Wildrye Persistence and Performance in Riparian Areas
- Matt A. Sanderson *a,
- Martin van der Grintenb and
- Robert C. Stouta
Virginia wildrye (Elymus virginicus L.), a perennial cool-season grass native to the northeastern United States, grows in moist low ground and could be useful in revegetating riparian areas. In this field study, we compared six populations of Virginia wildrye originally collected from Maryland and New York with a commercial ecotype and a cultivar ('Omaha') on wet soils at three locations. All entries were transplanted into single-row field plots of 15 plants per plot at Wye, MD, Klingerstown, PA, and Big Flats, NY, in April 2004. Rows were oriented perpendicular to the slope so that each population was evaluated at the top, middle, and bottom slope positions. Survivorship, tillers per plant, and plant dry weight were assessed in 2007. Survivorship after 3 yr ranged from 57 to 76% for the six populations and averaged 85% for the ecotype and 77% for the cultivar. Tillers per plant ranged from 26 to 52 for the populations compared with 32 for the cultivar and 29 for the ecotype. Landscape position affected wildrye plants only at the Maryland site where frequently saturated soils at the bottom slope position reduced survivorship by 50%, tiller number by 60%, and plant dry weight by 82% compared with plants at the top of the slope. Most of the wild populations of Virginia wildrye were similar to the commercial cultivar and ecotype in survival, number of tillers per plant, and biomass indicating that locally adapted native populations can be used directly in conservation plantings.Please view the pdf by using the Full Text (PDF) link under 'View' to the left.
Copyright © 2010.


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text: Department of Pathology and Molecular Medicine Graduate Theses http://hdl.handle.net/1974/759 2017-08-23T23:22:21Z 2017-08-23T23:22:21Z Evaluation of the determinants and characterization of bleeding in hemophilia A and B carriers Candy, Victoria http://hdl.handle.net/1974/15910 2017-08-10T12:20:27Z Evaluation of the determinants and characterization of bleeding in hemophilia A and B carriers Candy, Victoria Hemophilia A and B are bleeding disorders caused by a deficiency in coagulation factor VIII (FVIII) or coagulation factor IX (FIX), respectively. Due to the X-linked inheritance pattern, males are affected with the disease, while females are almost exclusively carriers of hemophilia. Although carriers were historically assumed to be asymptomatic, it is now known that many hemophilia carriers experience abnormal bleeding. Hemophilia carriers have higher bleeding scores compared to controls and have decreased health related quality of life. Despite this recognition, little is understood concerning the cause of this bleeding. As such, this study aims to evaluate hemophilia carrier bleeding to elucidate the cause of the abnormal bleeding phenotype. The objectives of this study are to evaluate hemophilia carrier bleeding in several contexts and with respect to numerous determinants of bleeding in order to elucidate the relative contribution of each determinant to the Self-administered Bleeding Assessment Tool (Self-BAT) bleeding score, and to examine the underlying pathophysiological mechanism of abnormal bleeding in hemophilia A carriers by comparing the response to desmopressin in hemophilia A carriers and controls. This study demonstrates that hemophilia carriers experience comparable levels of bleeding as women with other bleeding disorders and that there may be differences in the manifestation of bleeding between hemophilia A and B carriers. Importantly, we also demonstrate that increasing age, O-type blood, and low factor level may contribute to an abnormal bleeding phenotype in carriers. Additionally, we show that hemophilia A carriers, even with normal baseline FVIII levels, have a significantly reduced and less sustained FVIII responses to DDAVP compared to controls. To our knowledge, this is the first study to examine multiple determinants of bleeding in hemophilia carriers in a single study and the first to fully characterize the response to DDAVP in hemophilia A carriers compared to controls. In conclusion, these results have begun to elucidate the cause of hemophilia carrier bleeding. Ultimately, an improved understanding of what factors put a carrier at risk of abnormal bleeding and of the mechanism of this abnormal bleeding will allow for improved healthcare and quality of life for these women. Early mechanisms of factor VIII immunity in hemophilia A Lai, Jesse http://hdl.handle.net/1974/15907 2017-08-10T12:20:27Z Early mechanisms of factor VIII immunity in hemophilia A Lai, Jesse The most serious complication in treating hemophilia A (HA) is the development of an immune response to the therapeutically-administered factor VIII (FVIII). A better understanding of initiating events leading to FVIII immunity may highlight alternative treatment interventions. We have explored this synapse at the level of the FVIII protein, the cellular interactions, and the surrounding microenvironment. At the protein level, we have confirmed epidemiological findings suggesting that recombinant FVIII produced in a baby hamster kidney cell line is more immunogenic than FVIII produced in Chinese hamster ovary cell line. We have attributed this, in part, to differences in protein N-linked glycosylation, where incomplete occupancy of N-linked consensus sequences reveals epitopes for naturally circulating IgM antibodies. To elucidate cellular immune responses, we observed that human FVIII interacts initially with MARCO+ macrophages in the marginal zone of the mouse spleen. Functional enrichment analysis of the upregulated splenic transcriptome 3 hours after intravenous FVIII administration suggests a modulation of STAT1 and STAT3 signaling, while a similar analysis in the liver implicate Wnt signaling. Interestingly, an endocytic receptor has never been implicated in FVIII immunity in vivo. A GWAS study recently implicated a role of the endothelial cell scavenger receptor, stabilin-2, on circulating FVIII levels. Here, we showed that stabilin-2 knockout mice exhibit an attenuated immune response against FVIII compared to wildtype mice in a human von Willebrand factor-dependent manner. Lastly, we assessed the role of an inflammatory microenvironment on FVIII immunogenicity. The proximity of pediatric vaccination and the initiation of FVIII replacement therapy has prompted clinical concerns that concurrent exposure to inflammatory viral constituents may increase the risk of FVIII immune responses. In a transgenic HA mouse model, we have shown that intramuscular immunization against influenza decreases FVIII immune responses through a mechanism of antigenic competition leading to CD4+ T cell diversion towards the site of immunization. Collectively, these studies highlight potential areas for therapeutic intervention, and also provide clinicians with mechanistic evidence that may aid in the treatment of HA. The Role of TET2 in Macrophage Differentiation and Polarization Cull, Alyssa http://hdl.handle.net/1974/15414 2017-08-09T19:28:57Z The Role of TET2 in Macrophage Differentiation and Polarization Cull, Alyssa The epigenetic regulator Tet methylcytosine dioxygenase 2 (TET2) catalyzes the conversion of 5-methylcytosine (5-mC) to 5-hydroxymethylcytosine (5-hmC), leading to DNA demethylation. Inactivating TET2 mutations are common in myeloid cancers such as chronic myelomonocytic leukemia (CMML) and myelodysplastic syndromes (MDS). Little is known about the role of TET2 in disease-relevant monocytes/macrophages (MΦs). Therefore, our goals for this project were to characterize Tet expression during normal murine MΦ differentiation and polarization, examine the effect of Tet2-deficiency on broader MΦ polarization gene signatures, and determine the translatability of our murine findings to human MDS/CMML. In this thesis, we characterized the expression of Tet2 in murine MΦ differentiation and polarization. Using murine bone marrow-derived MΦs (BMMΦ), we observed that Tet2 was highly expressed in differentiated MΦs. Interestingly, differentiation-associated gene expression was not altered in Tet2-knockout BMMΦs and peritoneal MΦs (PMΦs), suggesting that Tet2 is dispensable for MΦ development. MΦ response to polarizing stimuli was then explored. Tet2 transcript levels increase early in the LPS response. The NFκB inhibitor compound BAY11-7082 was shown to abolish LPS-mediated Tet2 induction, indicating that this gene is NFκB-responsive. Exploring Tet2-deficiency, we characterized the phenotype of Tet2-knockout MΦs using NanoString gene expression analysis. Constitutive expression of LPS-induced genes was observed in resting state Tet2-deficient PMΦs. In particular, we noted increased Il1β and Il6, as well as the anti-inflammatory gene Arginase 1 (Arg1), in resting Tet2-deficient PMΦs and in LPS-treated Tet2-knockout BMMΦs. These results implicated Tet2 loss in the establishment of aberrant inflammation, raising the question of whether TET2-mutant MΦs participate in altering the immune microenvironment. Assessing immune dysregulation in TET2-mutant cells, we assayed IL1β and IL6 mRNA expression in human MDS/CMML patient samples as well as MDS/CMML-derived human MΦs. While levels of both targets were variable, some TET2-mutant cells had high IL6 expression. We also assessed ARG1 expression in MDS/CMML BM biopsies using immunohistochemical analysis. TET2 and/or DNMT3A mutations were correlated with high ARG1 staining, providing a link between ARG1 overexpression and TET2 mutations in humans. Overall, the work presented in this thesis provides a novel connection that ties TET2 lesions to the development of an inflammatory MDS/CMML local microenvironment. Regulation of HC11 Mouse Mammary Epithelial Cell Differentiation by the Rac/Stat3 axis Niit, Maximilian http://hdl.handle.net/1974/15332 2017-08-11T17:20:12Z Regulation of HC11 Mouse Mammary Epithelial Cell Differentiation by the Rac/Stat3 axis Niit, Maximilian Studying cellular differentiation can reveal valuable information underlying the mechanisms that mediate cell fate. The HC11 mouse mammary epithelial cell line has long been used as a model to study lactogenic differentiation in vitro. Differentiation of HC11 cells requires the addition of hydrocortisone, insulin, and prolactin, added at confluence. Recently, our lab demonstrated that engagement of E-cadherin in HC11 cells, which is favoured under conditions of confluence, triggers a dramatic increase in the activity of the cRac1, small GTPase, which, in turn, activates Stat3 (Signal Transducer and Activator of Transcription-3). Therefore, we hypothesized that the E-cadherin/Rac/Stat3 axis may play a role in HC11 cell differentiation. My results demonstrate that this pathway positively regulates HC11 mammary epithelial cell differentiation and that it is a key mediator of cell fate. Particularly, the strength of the Rac signal is key for the outcome of the differentiation process; cRac is critically required for differentiation, and at low levels, mutationally activated RacV12 is able to increase differentiation, presumably by reinforcing the E-cadherin/Rac differentiative signal. However, high RacV12 expression blocked differentiation while inducing neoplastic transformation. On the other hand, despite the fact that Stat3 was also required for differentiation, constitutively active Stat3 expression was found to block differentiation at all levels. In conclusion, hyperactive RacV12 may have opposing functions, depending upon its level of expression. As a result, a complete Rac inhibition may not be necessary in order to reverse a Rac-driven, neoplastic phenotype in a clinical setting, since the residual, low levels of Rac may be actually promoting cellular differentiation, a finding which could have important therapeutic implications.