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Skip to comments.Tuberculosis May Lurk in Bone Marrow Stem Cells of Infected Patients
Posted on 02/06/2013 2:29:08 PM PST by neverdem
Tuberculosis is a devastating disease that kills nearly 2 million people worldwide each year. Although antibiotics exist that can ameliorate the symptoms, the courses of therapy last for months and don't completely eradicate the disease, which frequently recurs years or decades after the initial treatment.
Now, in a classic case of bench-to-bedside research, scientists at the Stanford University School of Medicine have discovered a possible reason for the disease's resistance: The ability of the tuberculosis bacteria to infiltrate and settle down in a particular class of stem cell in the bone marrow. By doing so, the bacteria take advantage of the body's own mechanisms of self-renewal.
"Cancer scientists have noted that self-renewing stem cells like these in the bone marrow have properties -- such as natural drug resistance, infrequent division and a privileged immune status -- that make them resistant to many types of treatment," said Dean Felsher, MD, PhD, professor of oncology and of pathology. "Now it turns out that this ancient organism, Mycobacterium tuberculosis, figured out a long time ago that, for the same reasons, these cells are ideal hosts to invade and in which to hide."
Not only did the scientists find genetic material from the bacteria inside the stem cells, they were also able to isolate active bacteria from the cells of human patients with tuberculosis who had undergone extensive treatment for the disease. The findings raise the possibility that other infectious agents may employ similar "wolf-in-stem-cell-clothing" tactics. And, although any new human treatments are likely to still be years away, they suggest a new possible target in the fight against tuberculosis, which infects nearly 2.2 billion people worldwide.
"We now need to learn how the bacteria find and infect this tiny population of stem cells, and what triggers it to reactivate years or decades after..."
(Excerpt) Read more at sciencedaily.com ...
CD271+ Bone Marrow Mesenchymal Stem Cells May Provide a Niche for Dormant Mycobacterium tuberculosis
MSCs were first isolated as adherent cells cultured from bone marrow and are non-phagocytic, exhibit a fibroblast-like phenotype, and are able to differentiate into adipose, tendon, muscle, bone, and cartilage in vitro [20].
MSCs are Mesenchymal Stem Cells.
A third of the world has TB? I find that statistic hard to believe.
Google the worldwide prevalence of it. It's a common estimate. It's called latent TB. People don't have symptoms, at least not yet.
"Hematopoeitic cells, especially macrophages, have long been thought of as the primary intracellular niche for M. tuberculosis, even when the infection is present at a very low levels and the individual is asymptomatic," said Kevin Urdahl, MD, PhD, an assistant professor at Seattle Biomedical Research Institute, the country's largest independent organization devoted to the study of infectious diseases. Urdahl was not involved in the research. "However, this study shows that the bacteria also has the capacity to reside within mesenchymal stem cells, and may even persist in these cells after drug treatment. Although further studies will be needed to establish the relative importance of this niche during latent infection, the immunoprivileged nature of the bone marrow and the ability of mesenchymal stem cells to express drug efflux pumps make this an intriguing possibility that could have important clinical implications."
Guess I should get some tests done again.
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Girl for Girl (2000)
Jeff, Ben, and Paul, the main characters of Girl for Girl (2000), have it all. On top of their startup internet company's booming success, each has his own booby beauty doing her duty to keep her man happy. Using technology to test the loyalty of their ladies, the boys set out to see if their gorgeous girlfriends are really vicious gold diggers by monitoring their daily actions in cyberspace. With pro video vixens like Tracy Ryan, Kelli McCarty, and Flower Edwards steaming up the screen,...Join Mr. Skin for the full review >>

subset: commoncrawl


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3921 Sherman Ave, St. Joseph, MO 64506
Mini implants are an alternative to conventional implants. As implied by their name, they are smaller than regular implants, about half the width. Mini implants are most often suggested for patients whose bone width is not dense enough to support regular implants. They can be used to stabilize dentures or a restoration for a small tooth, front tooth, or teeth located in a narrow space.
The procedure for placing mini implants is much quicker and less invasive than that of placing traditional implants. Because they are small, there is no need for complex surgery, and they are usually placed in one visit. During the procedure:
The minimally invasive procedure also allows for a much faster healing process. Plus, there isn't as significant of a disturbance to the bone and tissue, so the procedure doesn't cause a great amount of discomfort.
Cost-wise, mini implants are less expensive than regular implants, making them an affordable option as well. To find out if you might be a candidate for mini implants, call our office to schedule a consultation.


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i know this sounds redic, but it does! people always say I'm cute/adorable/cherubic, and supposedly its a "good" thing if boys think your cute but how come it doesn't feel like it? the fine and hot girls get all the attention and boyfriends. is cute a less attractive version of hot?
because its nice that they think of you in a girlfriend way, but isn't that like saying a cute girl is not as pretty as a hot/sexy girl? it makes me feel like there settling on my looks because they know I'm not the cheating type or something! =(
so I have a couple questions: is that really what that means? if cute means your less attractive, what can a cute girl do to make herself hot?
Most Helpful Guy
Some guys think it is offensive to call a girl hot, so instead they call her cute.11|00|0


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Asics Gel Lyte V In Atomic Blue/Black Available Now
Wednesday Aug 13 2014
Asics delivers another colorway of their popular Gel Lyte V ($110) model for the upcoming Fall season. The sneaker features an atomic blue mesh and neoprene upper alongside sandy suede panels. Finished with a cushioned white midsole and hints of 3M the heel tab, these runners are a great silhouette for the fall season. Phone Orders 702-463-3322 or email@example.com. International Shipping available.
-Kevin Sanchez
[nggallery id=2041]
-Kevin Sanchez
[nggallery id=2041]


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Data from: Hybridization, natural selection and evolution of reproductive isolation: a 25-years survey of an artificial sympatric area between two mosquito sibling species of the Aedes mariae complex
Date Published: June 30, 2014
DOI: http://dx.doi.org/10.5061/dryad.39qf1
Content in the Dryad Digital Repository is offered "as is." By downloading files, you agree to the Dryad Terms of Service. To the extent possible under law, the authors have waived all copyright and related or neighboring rights to this data.
|Simulated multilocus genotypes of Aedes mariae and Aedes zammitii
|7 times
|Simulated multilocus genotypes of Aedes mariae and Aedes zammitii for six allozymic loci. From multilocus genotypes of 100 individuals of Ae. mariae from Circeo and Scauri populations and 100 individuals of Ae. zammitii from Peschici and Baia dei Campi populations sampled in 1985, we simulated 1000 individuals of each of five genotypic class (parental Ae. mariae and Ae. zammitti, F1, F2 and first-generation backcrosses) using the software hybridlab version 1.0. z0s = Ae. zammitii from Peschici and Baia dei Campi populations; z1s = Ae. mariae from Circeo and Scauri populations.
|simulated data_Aedes mariae_Aedes zammitii.dat (154.6 Kb)
|View File Details
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"Jorge was the consummate professional, very patient and accommodating as well as answering a thousand questions"
- Diane, Saskatchewan -
Day trip with driver Jorge to Uxmal and sights along the way
They're fun, they're original and they are whatever you want them to be. No fixed schedules or itineraries. We design tours that are all about YOU. Contact us to design a customized tour for your Yucatan visit! firstname.lastname@example.com
|Flagstones to the Machine Room, Tepich
|Modern Art aka Grafitti, Tepich
|Machine room, Tepich
|Square (unusual) chimney, Tepich
|Original stones in the entryway, Kankirixche
|The main building, Kankirixche
|Hurricane damage, Kankirixche
|A stone crushing machine from the turn of the century, Kankirxche


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I am providing an early release of this add-on which will add a table BBCode to your XenForo boards. There is a vbulletin mod that makes it possible to include tabular data in posts using an easy to use syntax. I have tried to use a similar syntax. At the moment this add-on provides only the option of specifying column headers. If no column headers are specified, some default columns headers are included. These are necessary in order to make it work with the DataTables jquery plugin that is used in this add-on.
Following is the code with the head option specified.
one | two | three
1 | 2 |
4 | 5 | 6
7 | 8 |
This produces the table shown in the following figure.
As shown in the above figure, bbcodes and similies are parsed inside the table cells. The following figure shows the same table, this time with the head option removed and hence with the default column headers.
Please note that this is an early release. I will welcome your suggestions for making this add-on better. At some point in time, I might add more options to customize the look and feel of the tables. The choice of the DataTables jquery plugin was rather arbitrary. I will look into the possibility of using other jquery table/grid plugins with this add-on.


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MemoryMappedFile::CreateViewStream Method (Int64, Int64, MemoryMappedFileAccess)
Creates a stream that maps to a view of the memory-mapped file, and that has the specified offset, size, and access type.
Assembly: System.Core (in System.Core.dll)
[SecurityPermissionAttribute(SecurityAction::Demand, Flags = SecurityPermissionFlag::UnmanagedCode)] public: MemoryMappedViewStream^ CreateViewStream( long long offset, long long size, MemoryMappedFileAccess access )
- offset
- Type: System::Int64
The byte at which to start the view.
- size
- Type: System::Int64
The size of the view. Specify 0 (zero) to create a view that starts at offset and ends approximately at the end of the memory-mapped file.
- access
- Type: System.IO.MemoryMappedFiles::MemoryMappedFileAccess
One of the enumeration values that specifies the type of access allowed to the memory-mapped file. The default is ReadWrite.
Return ValueType: System.IO.MemoryMappedFiles::MemoryMappedViewStream
A stream of memory that has the specified characteristics.
offset or size is a negative value.
size is greater than the logical address space.
access is not a valid MemoryMappedFileAccess enumeration value.
access is invalid for the memory-mapped file.
size is greater than the total virtual memory.
access is invalid for the memory-mapped file.
You can use the stream returned by this method for sequential access to a memory-mapped file, such as for inter-process communications.
To create a complete view of the memory-mapped file, specify 0 (zero) for the size parameter. If you do this, the size of the view might be smaller or larger than the size of the source file on disk. This is because views are provided in units of system pages, and the size of the view is rounded up to the next system page size.
Windows 7, Windows Vista SP1 or later, Windows XP SP3, Windows Server 2008 (Server Core not supported), Windows Server 2008 R2 (Server Core supported with SP1 or later), Windows Server 2003 SP2
The .NET Framework does not support all versions of every platform. For a list of the supported versions, see .NET Framework System Requirements.


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Chocolate Cherry Smoothie – Nothing like an antioxidant and protein boost that tastes like dessert!
Earlier this year, my sister's friend posted a Facebook status along the lines of: "ah, Mondays. The day I throw a bag of soggy spinach into the trash and buy a new bag, which will sit in my fridge until next week." It made me laugh so hard! I've been there. Sometimes, I have the best of intentions, but I forget about something or leave it a bit too long. I've got a post in the works about how to cut down on kitchen waste, but for now, my favorite method for spinach is smoothies.
These chocolate cherry smoothies taste so fudgy and rich, we love them AND not a soul in my house other than me even knows they contain spinach. That feels like winning.
It's made from healthy enough ingredients that it's an easy breakfast or snack, but has all the flavor of dessert (my favorite!). Chocolate Cherry Smoothie for the win!
Notes on the Recipe:
Sweets for the sweet. Depending on how sweet your cherries are, you may want to add 1-2 tsp of pure maple syrup to the smoothie. This is totally based on your preference. I don't mind adding a tiny bit of syrup if it helps my kids eat some greens!
Let's talk protein. My favorite protein powder is collagen. It's a very clean and nutrient-rich protein source. It's nondairy but is animal sourced, so it's not a great choice for vegans or vegetarians. For a vegan/vegetarian protein boost, a tablespoon or two of chia or hemp seeds blends in really well! You can certainly leave out any of the protein options, I've just found that they help prevent a sugar rush and keep me full longer.
If you don't have a high-speed blender… try pureeing your greens and milk before adding the other ingredients. This will help get you that velvety smooth finish, without any leftover pieces of spinach floating around. It was my go-to trick before I got my Blendtec.
Like this recipe? You might also like…
- 1 ripe banana
- 2 cups frozen cherries (I used sweet for this)
- 1 cup cashew or almond milk (can also use dairy or coconut milk)
- 1-2 cups spinach
- 2 Tbsp cacao or unsweetened cocoa powder
- ½ tsp vanilla extract
- 2-3 drops almond extract
- For protein: 2-4 Tbsp collagen powder or 1-2 Tbsp chia or hemp seeds (optional)
- optional: 2-3 tsp pure maple syrup (if needed/desired)
- Place all ingredients in the blender in the order listed. Puree until completely smooth, adding more milk if necessary. Taste and add maple syrup if needed or desired. Enjoy!


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Pilot Feasibility Study of the Safety and Efficacy of Anakinra in Heart Failure With Preserved Ejection Fraction
This study has been completed.
Virginia Commonwealth University
American Heart Association
Information provided by (Responsible Party):
Virginia Commonwealth University
ClinicalTrials.gov Identifier:
First received: February 23, 2012
Last updated: December 12, 2016
Last verified: December 2016
- Full Text View
- Tabular View
- Study Results
- Disclaimer
- How to Read a Study Record
This will be a randomized, double-blind, crossover pilot study to measure the safety and feasibility of Interleukin-1 (IL-1) blockade with Anakinra in patients with stable heart failure with preserved ejection fraction.
|Heart Failure
|Drug: Anakinra Drug: Placebo
|Study Type:
|Study Design:
|Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
|Official Title:
|Pilot Feasibility Study of the Safety and Efficacy of Anakinra in Heart Failure With Preserved Ejection Fraction
Resource links provided by NLM:
MedlinePlus related topics: Heart Failure
Drug Information available for: AnakinraU.S. FDA Resources
Further study details as provided by Virginia Commonwealth University:
Primary Outcome Measures:
- Peak Oxygen Consumption (Peak VO2) [ Time Frame: 14 days ]The primary endpoint is the change in peak oxygen consumption among stable heart failure patients (n = 12) following 14-days treatment with daily doses of Anakinra 100 mg (SC, subcutaneous).
Secondary Outcome Measures:
- Exercise Time [ Time Frame: 14 days ]Interval change from baseline in duration of exercise during a standardized cardiopulmonary exercise test upon completion of 2 weeks treatment
Other Outcome Measures:
- Correlation Between Endpoints [ Time Frame: 28 days ]Correlation between interval change in peak VO2 and high sensitivity C-reactive protein
- Heart Failure Symptoms (DASI) [ Time Frame: 28 days ]Interval change from baseline in Heart Failure (HF) symptoms as measured by Duke Activity Status Index (DASI) upon completion of 2 weeks treatment.
- Adverse Events [ Time Frame: 28 days ]Additional endpoints will include assessment of adverse events and hospitalizations during 4-week duration of study.
- Inflammatory Biomarkers [ Time Frame: 28 days ]Interval change from baseline in high-sensitivity C-reactive protein upon completion of 2 weeks treatment.
- Ventilatory Efficiency (VE/VCO2 [Carbon Dioxide] Slope) [ Time Frame: 14 days ]Interval change from baseline in ventilatory efficiency (VE/VCO2 slope) upon completion of 2 weeks treatment.
|Study Start Date:
|February 2012
|Study Completion Date:
|June 2013
|Primary Completion Date:
|June 2013 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: Anakinra
Treatment with daily subcutaneous injections of Anakinra 100 mg
Drug: Anakinra
Anakinra 100 mg daily subcutaneous injection
Other Names:
Placebo Comparator: Placebo
Treatment with daily subcutaneous injection of placebo
Drug: Placebo
Placebo daily subcutaneous injection
Other Name: Sodium Chloride (NaCl) 0.9%
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Symptoms and signs of congestive heart failure
- Recent Imaging Study (<12 months) showing Left Ventricular Ejection Fraction (LVEF) >50% and Left Ventricular End Diastolic Volume Index (LVEDVI) <97ml/m2
Evidence of abnormal Left Ventricular (LV) relaxation, filling, diastolic distensibility, and diastolic stiffness as shown by one of the following:
Invasive Hemodynamic measurements
- mean Pulmonary Capillary Wedge pressure (mPCW) >12
- Left Ventricular End Diastolic Pressure (LVEDP) >16 mmHg
Tissue Doppler Echocardiogram
E/E' 8-15 and one of the following
- Left Ventricular Hypertrophy (LVH)
- Atrial Fibrillation
- Left Atrial Enlargement
- E/A <0.5 + Deceleration Time (DT) >280 (if >50yrs of age)
- Biomarkers
- Brain Natriuretic Peptide (BNP) >200pg/mL
Exclusion Criteria:
- Age <18
- Recent changes (previous 3 months) in HF maintenance medications (beta-blockers, angiotensin converting enzyme [ACE] inhibitors, aldosterone antagonists, vasodilators, cardiac glycosides, diuretics)
- Hospitalization for worsening Heart Failure (HF) or acute decompensated HF within the previous 12months
- Anticipated need for cardiac resynchronization therapy (CRT) or automated-implantable cardioverter defibrillator (AICD)
- Angina or electrocardiograph (ECG) changes that limit maximum exertion during cardiopulmonary exercise testing
- Active infection including chronic infection
- Active cancer
- Recent (<14 days) use of anti-inflammatory drugs (not including Non-Steroidal Anti-Inflammatory Drugs [NSAIDs]), Chronic inflammatory disorder (including but not limited to rheumatoid arthritis, systemic lupus erythematosus), malignancy, or any comorbidity limiting survival or ability to complete the study
- Pregnancy (determined by urine pregnancy test in women of childbearing potential)
- Inability to give informed consent
- Other conditions limiting completion of cardiopulmonary exercise test or completion of the study
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01542502
Please refer to this study by its ClinicalTrials.gov identifier: NCT01542502
|United States, Virginia
|Virginia Commonwealth University
|Richmond, Virginia, United States, 23298
Sponsors and Collaborators
Virginia Commonwealth University
American Heart Association
|Principal Investigator:
|Antonio Abbate, MD, PhD
|Virginia Commonwealth University
More Information
Keywords provided by Virginia Commonwealth University:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on August 21, 2017
|Responsible Party:
|Virginia Commonwealth University
|ClinicalTrials.gov Identifier:
|NCT01542502 History of Changes
|Other Study ID Numbers:
|Study First Received:
|February 23, 2012
|Results First Received:
|August 19, 2014
|Last Updated:
|December 12, 2016
Keywords provided by Virginia Commonwealth University:
Heart failure with preserved ejection fraction
Diastolic heart failure
Aerobic exercise performance
Additional relevant MeSH terms:
Heart Failure
Heart Diseases
Cardiovascular Diseases
Interleukin 1 Receptor Antagonist Protein
Antirheumatic Agents
ClinicalTrials.gov processed this record on August 21, 2017


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- Doctors
- Florida
- Clearwater
- Cosmetic Surgeons / Physicians
- Dr. Noel Tenenbaum
You may also like
Ratings for Dr. Noel Tenenbaum
First off - Terrible bedside manner. I went to him to have my old saline implants replaced with HP silicone. My right breast is now completely displaced and I've seen in 4 times and he says it's symmetrical. He's a terrible surgeon and there is absolutely a reason why he's begging for customers via Groupon. Please spend the extra money and go elsewhere!
Great professional doc and staff. Explained everything well. Def. Recommend
Got smart Lipo done on lower abdomen was told if results were not good he would touch up after. After reaching out numerous times and going to the office to express my concerns he is Now is refusing to touch up and recommended I need a tummy tuck for $3000 more dollars. Not happy at all.
I had a complete facelift and Lowe lids in October. I went to 4 different Drs around the Tampa Bay Area. Met with Dr Tenenbaum. Agreed for him to do the work because his prices were so right for my budget but most importantly, I liked his bed side manners. He was professional and to the point. My gut felt good about him. After giving money down, I went on site to read the reviews. That scared the heck out of me so I called the office, spoke to Stephanie to let her know my concerns on the negative remarks. She asked me to meet with the Doctor. So I did. 3 times prior to surgery. I asked if I could talk to some patients who have used him. They all called me. I felt better but still apprehensive. I had the surgery and was surprised that it was more major than what I had anticipated. I guess I thought I would be in and out and back to work in 4-5 days. Wrong on my part. 2 weeks and I felt comfortable to go out in public. Not ready completely though. The surgery center nursers were incredibly good, friendly and caring. Dr Tenenbaum was on time. Reassured me and took time to answer all my questions until I was comfortable then off to surgery. I am still healing but for the most part I'm really Pleased with the outcome. There have been minor issues but again, I realize it's surgery. Dr Tenenbaum has been wonderful and patient and there for me when I need to ask questions. His office is nice. His staff is great! I have referred a friend to him and she is pleased and happy how she looks. So is her husband. She is in her mid 70's. I would not mind if you called me for a reference.
Today is post op day 1 of my bilateral breast augmentation surgery. I went with saline. So far, it has been an absolutely wonderful experience! I am ALREADY SEEING that he delivered great results (and this is only the first day). He's short, sweet, and to the point. He was efficient, yet thorough. He answered all my questions, and was super nice. I'm really happy with my results so far, and so far this whole experience has been great. His OR staff and group at Orthopaedic Surgery Center of Clearwater were excellent. Super nice staff, and they were also super efficient as well. Go see this man for some nice boobies! I recommended my best friend to go see him for her breasts as well.
He is a terrible doctor. He is extremely insensitive. The procedure was useless, the whole time the the doctor is telling you everything is fine. I was concerned about scarring and he dismissed it as if it would be normal and didn't offer any solution what so ever.
Seriously RUN ! I honestly don't know how he stays in business . There is a reason he is on Groupon . Don't trust your face or body to this man . When there is a problem he will just tell you its normal . Pay more and get good results . Its just not worth it
I've had nothing but great experiences and results through five visits
He is a complete joke. I went to Dr. T after having gastric bypass and losing 115 lbs. he said he was completely competent in re-constructive surgery. This was obviously not the case. He did a "lift" and implants to my breasts. A few weeks after The surgery it was very obvious that my right breast settled semi-normal. However my left breast was no where near symmetrical. I went back to see Dr. Tenenbaum and he said it was "just my body. I lost 9 lbs since surgery etc etc." I have gone to see 3 different plastic surgeons for their opinions since and there is no excuse that my left implant falls under my armpit every time I lay down and i look like I have old saggy breasts. He is a fraud and makes excuses for his terrble work.
I would highly recommend this doctor to the Tampa Bay area. I have had noting but a very good experience with Dr. Tenenbaum and his office manager and nurse. He truly is a doctor committed to his patients and cares about them.
Dr. Noel Tenenbaum's Credentials
Facility Affiliations
Accepting New Patients
- University Of Vermont College Of Medicine (Grad. 1986)
Other Specialties
Areas of Expertise
Awards & Recognitions
Publications & Research
Insurance accepted by this Doctor
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$50.00 $125.00
The Sienna jumpsuit has been playfully designed. Created in super soft, lightweight rayon in our exclusive vintage floral print and featuring a deep scoop neck, dramatic cutaway back, adjustable straps, button detailing and finished with a delicately gathered waist and culotte style shorts. Pair with your well-worn converse to give this flirty little jumpsuit a tomboy edge.
BUST- XS 83cm, S 88cm, M 93cm, L 98cm
WAIST- XS 76cm, S 81cm, M 86cm, L 91cm
HIP– XS 115cm, S 120cm, M 125cm, L 130cm


text:
Myotonic Dystrophy type 1 (DM1) is a complex neuromuscular disease characterized by skeletal muscle wasting, weakness, myotonia and insulin resistance. DM1 is caused by the expanded RNA CUG repeats that misregulate RNA homeostasis through RNA-binding proteins, CUGBP1 and MBNL1. Therapeutic approaches for DM1 reducing toxicity of the mutant CUG repeats are actively developing;however, there is still no cure for DM1. Here we propose to examine the hypothesis that the genetic inhibition of Glycogen Synthase kinase 3b (GSK3b) improves skeletal muscle pathology in the DM1 mouse model. We found that the mutant CUG repeats increase enzymatic activity and the levels of GSK3b in skeletal muscle biopsies from patients with DM1 and in skeletal muscle of the DM1 mouse model, HSALR mice. We showed that the treatments of HSALR mice with lithium (Li), a known inhibitor of GSK3b, or with the potent inhibitor of GSK3b, TDZD-8, reduce the number of fibers with internal nuclei, increase grip strength and reduce myotonia. Such improvement of muscle pathology in the HSALR mice was accompanied by the normalization of GSK3b activity and by correction of expression of one of the GSK3b substrates, cyclin D3. The correction of cyclin D3 by the inhibition of GSK3b leads to the reduction of the suppressive form of CUGBP1, which causes skeletal muscle atrophy and weakness. Since these GSK3 inhibitors reduce both GSK3b and GSK3a, Specific Aim 1 of this proposal will examine if a genetic reduction of GSK3b in HSALR mice will lead to the reduction of DM1 muscle pathology. To achieve the genetic reduction of GSK3b, muscle specific GSK3b knock out (SbKO) mice are crossed with HSALR mice, producing HSALR/SbKO mice. Improvement of muscle pathology in HSALR/SbKO mice will provide a background for the development of therapy for DM1 patients which will be based on the inhibitors of GSK3. Since Li is approved by FDA to treat mood diseases and because potent inhibitors of GSK3b are used in the pre-clinical studies for other diseases, the application of these inhibitors might accelerate the development of DM1 therapy using GSK3b inhibitors. The increase of GSK3b in DM1 muscle suggests that other substrates of GSK3b might be also altered in DM1. Patients with DM1 have a predisposition to Type 2 Diabetes (T2D). It is known, that GSK3b is increased in skeletal muscle of patients with T2D. The increase of GSK3b in T2D causes a reduction of the activity of glycogen synthase that leads to the reduction of the glycogen synthesis and alteration of glucose metabolism. We hypothesize that the increase of GSK3b in skeletal muscle of HSALR mice causes glucose and insulin insensitivity and predisposition to T2D. This hypothesis will be tested in the Aim 2. In summary, our study will show if the genetic inhibition of GSK3b might improve muscle pathology and enhance insulin and glucose sensitivity in the DM1 mouse model. The knowledge, obtained in mouse model of DM1, will be translated to the clinical therapy of DM1.
Myotonic Dystrophy type 1 is a multisystem disease without cure. We propose to apply basic science expertise to determine the role of the genetic inhibition of GSK3b kinase in the improvement of muscle dysfunction in DM1. The knowledge, obtained in the mouse model of DM1, will be translated to the development of the therapeutic interventions in DM1.
|Breaux, Meghan; Lewis, Kyle; Valanejad, Leila et al. (2015) p300 Regulates Liver Functions by Controlling p53 and C/EBP Family Proteins through Multiple Signaling Pathways. Mol Cell Biol 35:3005-16
|Jones, Karlie; Wei, Christina; Schoser, Benedikt et al. (2015) Reduction of toxic RNAs in myotonic dystrophies type 1 and type 2 by the RNA helicase p68/DDX5. Proc Natl Acad Sci U S A 112:8041-5


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Panasonic DMP-BD655K The Panasonic DMP-BD655K is a Blu-ray
The BD-S667 is the perfect match for the RX-Vx67 series AV
Toshiba BDX1100 The Toshiba BDX1100 is a Blu-ray player that
Toshiba BDX3100 The Toshiba BDX3100 is a Blu-ray player that
Sony Internet TV Blu-ray Disc Player The Sony Internet TV is
Sony NSZ-GT1 The Sony NSZ-GT1 is a BD-Live (Profile 2.0)
Enjoy high definition with Blu-ray Disc playback and BD-Live
Enjoy high definition with Blu-ray Disc playback and BD Live
Enjoy the thrill of full high definition pictures delivered by
Enjoy the thrill of full high definition pictures delivered by
Philips BDP8000 The Philips BDP8000 is a Blu-ray player
Con funzionalità così convincenti, il nuovo 650BD potrebbe
Step into the 3D World™. Watch 3D movies at home with Full HD 3D
The NAD T587 is a solidly built, high quality, Profile 2.0
Panasonic DMP-BD45 The Panasonic DMP-BD45 is a Blu-ray
Now you can enjoy the best of 1080p video on your AQUOS ® LCD
BD-Profile2.0(BD-Live), BD-Java, BONUS VIEW support Plays
Stay Web-connected with Samsung Apps Samsung's exclusive
Cinema-quality resolution with 1080p HD 1080p HD provides
Samsung BD-C7900 The Samsung BD-C7900 is a digital media
Samsung BD-C6800 The Samsung BD-C6800 is a digital media
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Panasonic DMP-BDT100 The Panasonic DMP-BDT100 is a Full HD
Stay entertained with the BDP-S780 3D Blu-ray Disc player.
1080p High-Definition Picture as the Director Intended Pioneer's
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text:
Mississippi Criminal and Traffic Law Manual
Select a format
Product details
The Mississippi Criminal and Traffic Law Manual contains the statutes from the official Mississippi Code of 1972 Annotated that law enforcement professionals and trial attorneys need most often. Fully indexed and featuring a table of sections affected by recent legislation.
The Manual boasts an important feature that only LexisNexis can provide: concise summaries of the U.S. Supreme Court's treatment of complex constitutional issues surrounding criminal and traffic laws, drawn from the U.S. Supreme Court Reporter, Lawyer's Edition 2d. Over 50 specific topics are covered, including Arrest, Stop and Frisk, Search and Seizure, and Right to Counsel.
Features At-A-Glance:
Summaries of important U.S. Supreme Court decisions
Comprehensive index and table of contents
Table of Sections Affected by Recent Legislation
Table of Contents
(Selected Highlights)
Criminal Procedure
Motor Vehicle and Traffic Regulations
Public Safety and Good Order
Prisons and Prisoners
Alcoholic Beverages
Domestic Relations
The Supreme Court on Selected Criminal and Traffic Issues
and more!


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Report summaryTabasco has been developed as a satellite field within the Kuparuk River Unit on Alaska's North Slope. Tabasco began producing in May 1998. The field lies to the west of the Kuparuk field and is produced through the Kuparuk facilities. ParticipationConocoPhillips is the operator of the Tabasco field. BP, Chevron and ExxonMobil hold the remaining field equity. In 2000, BP acquired ARCO. In order for the deal to be completed, the Federal Trade Commission (FTC) required BP to divest ...
What's included?
This report includes 2 file(s)
- Tabasco (Kuparuk River Unit) PDF - 802.56 KB 10 Pages, 6 Tables, 7 Figures
- Tabasco (Kuparuk River Unit) XLS - 241.00 KB


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Garbage Removal $80.00
We offer the lowest prices on the south shore. You can fill the whole 8 foot bed of my truck with whatever you want for just $80 dollars!!! You can't find a better deal around than that. We also do scrap metal removal and do the best clean out job on the south shore. Call Steve!


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Question: Discuss three common denial techniques used by fraudsters
Discuss three common denial techniques used by fraudsters.
View Solution:
View Solution:
Answer to relevant QuestionsCompare and contrast high and low self control. How do these conditions impact a person's propensity to commit fraud?1. When a fraudster concludes that his or her fraudulent act is justified because of some prior action by the victim that caused harm to the fraudster, this is called:a. Conceptualizationb. Remediationc. Retributiond. ...Obtain the 2007 Oversight Systems Report on Corporate Fraud. After reviewing this report, respond to the following questions:a. How has the prevalence of fraud changed since 2005?b. What are the primary reasons that ...Identify three common neutralization techniques and briefly discuss each.Identify and describe first-, second-, third-, and fourth-party data.
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Hey everyone, it's been a while since I last posted. I was definitely saddened to find out the news about the forums, though several of you knew far in advance, it seems. I know I haven't been a member of this site for very long (since April or May of 2016), but I have had a great time here nonetheless. This has to be one of the most positive, supportive communities out there, especially for a franchise that has lasted this long. Then again, R&C has offered so much to the fans over the years with games that took risks and innovated, as well as newcomers, with the highly successful R&C 1 re-imagining. It's no surprise that a series this vast has a dedicated, even hardcore, fanbase that continue to drive its overall success.
I have read through this thread, so I know about the alternative platforms to talk to other fans on. The truth is, I'm not very keen on social media and its many apps, and actually prefer forums for direct discussions/conversations. I know that probably makes me a dinosaur (sometimes, I feel like one when it comes to gaming), but social media, and what it has become, just doesn't do it for me. At the very least, I will attempt to post more frequently than I have been until May 1, that very fateful day.
We can all take comfort in the fact that everything from these forums will be archived and readable, so taking a trip down Memory Lane will be an option


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Computer Repair $30.00
We have been in the same location for 16 years. In Huntington Park, CA. We open 7 days a week from 10am - 10pm.
We also, have 30 computer systems for rent, if you need to access internet or do work.
Give us a try, if your system is
- running slow
- Pop-ups
- Freezes
- restarts.


text: In 2016, Ultranationalist forces led an armed assault on Severny Island in the north of Russia. Catching the Army troops stationed there offf guard, they gained control of the island, and its nuclear silo. They then proceeded to threaten to unleash the WMD on the capital, if the government did not step down from office. The President of Russia, seeing the significance of this event, secretly sent messages to the United States, seeking help. In turn, the United States sent for help from other NATO countries and thus assembled an international special ops team consisting of the best from around the world.


text: thers no named theme song for itachi uchiha Retrieved from "http://answers.wikia.com/wiki/What_is_Itachi%27s_Theme_Song?oldid=3092003" Ad blocker interference detected! Wikia is a free-to-use site that makes money from advertising. We have a modified experience for viewers using ad blockers Wikia is not accessible if you've made further modifications. Remove the custom ad blocker rule(s) and the page will load as expected. Categories: Naruto Answered questions Add category Cancel Save


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First time home buyer
I've been private renting in the MOD property for more than 3 years now in Old Sarum in Salisbury and my family and I have settled in very well. Is there a chance of buying the property?
Asked on Feb 4 2014, Using Zoopla in Salisbury | Report content
Answers (1)
Depends on a lot of factors - credit rating needs to be perfect. Is the property available?Answered on Feb 5 2014, Report content
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The vehicle in your driveway is head and shoulders above the rest compared to all the other vehicles currently being driven today. You picked your Monza because its dependability and long-lasting quality struck a chord inside you; so why would you be okay with second best when it comes to great quality auto parts? Chevrolet automobile drivers have come to expect a certain level of reliability when driving their Monza around town. Anyone who drives a Chevrolet knows that when it comes to maintaining their vehicle only the most superior replacement parts will do.
You may not know it, but inside your engine there is a cacophony of vibration. The harmonic balancer contains a large rubber membrane that addresses this issue. The harmonic balancer is synonymous with your crankshaft pulley; absorbing vibrations while also connecting to all the accessories in your Chevrolet Monza engine via a system of drive belts. Since these accessories require the centrifugal force of the crankshaft to power them but would be severely harmed if the vibrations were transferred through the belts, your Chevrolet Monza harmonic balancer's rubber core soaks up that vibration so none of the other accessory pulleys get shaken to bits.
Ordering new Chevrolet parts from www.carpartsdiscount.com means you are paying the lowest prices for the highest quality original and aftermarket replacement Monza parts on the internet. Bring your Monza back to life with the highest quality repair parts from the experts at Car Parts Discount. Don't let a Harmonic Balancer repair spell the end of your car, truck, or SUV, and don't risk lowering its resale value by using anything but the highest quality repair parts. If your car or truck was built in 1980, 1979, 1978, 1977, 1976, 1975, then you will find the correct Chevrolet Monza Harmonic Balancer parts right here.


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Drag the button below to your bookmarks bar. Then click to change any webpage into one that's full of love, positivity and acceptance.Wholesomize ❤ It
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Love takes many forms. But the Wholesome Button is best experienced on a computer. Visit Wholesomize.It from your laptop or desktop to add the Wholesome Button.
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text: While skinny jeans are fast establishing themselves as a modern classic, there are plenty of other styles to explore if you're growing weary of denim that fits like a second skin. Check out the video below, where ASOS Stylist James Welsh walks you through a few wider-legged options for autumn. And, if you want to peruse the other cuts, colours and washes available to you, dive into our new jeans guide – the denim's lovely.


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Given the political season here in the United States, I thought it was time for rebroadcast of this 5/8/15 post. Notice: This was a difficult post for me to write. As you will see it is very different from the usual sort of things you might find here at Bliss Habits. I hope this does Read More
A New Years Prayer
Happy New Year!! I have a sweet treat for you today! Our resident poet January has a New Year's Prayer for us!! New Years Prayer by January Handl Make my bonds of love flexible, responsive, awake, alive. Make the silver threaded connections to the beautifully- broken beings course with a love that they Read More
It Cannot be Unplanted.
This is a rebroadcast of a 2012 post. Please enjoy 🙂 I am so grateful for the counsel of the children in my life. As always they lead me to the simple truths. In a family where rescuing cats and kittens comes way too often Tamara's daughter Natasha knows yes isn't always possible yet Read More
The End of Bliss Habits (or Reflections on #WDS2015 Part One)
If you follow along on our Bliss Habits page you probably already know that I recently attended The World Domination Summit. Once again the experience has proven to be quite powerful. The first speaker at this year's conference was Jon Acuff. I'm not sure what rock I've been living under but I hadn't previously heard Read More
Inviting an Ocean of Possibility with Trust
Tamara explains her photo. "It's Sparkle, one of the feral cats. He's the only one who climbs up on the porch chair to look in the window. I always feed them first thing each morning. He is always there looking in the window at me expectantly, trusting I am on my way, any minute now Read More
Such a small thing…
Welcome to Kindness week! I've been eagerly awaiting this week. So simple and so profound, kindness has a way of changing and fortifying lives. One of it's wonders is the ability to transform both the giver and receiver. January shares this brilliantly in these two poems: Gratitude for the Sun by January Handl Read More


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Orange County's Food Banks Need You!
We talk a lot about great places to eat, both cheap and not, and about farmers' markets and food trends (cupcakes, the guy with the hook is standing just off-stage...) and where to get the very best this or that, but not everyone has the luxury of being able to afford to do that.
Please think about donating to a food bank or soup kitchen this holiday season. Every little bit helps, and it's a good deed, whether you call it alms, tzedakah, charity or just plain generosity.
Honestly, while can drives and shelf-stable baskets of food all help, the single best donation you can make is money. Food banks don't eat up much money in administrative overhead, and the people who run them are unbelievably good at turning cash into the maximum amount of food possible. A gift of food will be used to feed people for the holidays; a gift of money can be used after the holidays, because the hungry don't magically disappear on January 2.
I'm not going to single out any one food bank for special attention, because every food bank can use your help, but if you need suggestions, please leave a comment.
Thanks, happy holidays, and now back to your normal irreverent Stick A Fork In It.
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Toxic Sugars: How Sweet Treats Affect Your Skin
It's hard not to indulge on sweet treats, especially during the holiday season. However, you might want to reconsider that second sugar cookie when you find out what it'll do to your skin.
Eating too much sugar can lead to wrinkles and sagging skin. This is because sugar molecules attach to collagen and elastin proteins in the skin through a process called glycation. The process produces advanced glycosylation end products, or AGEs for short. AGEs are free radicals that lead to inflammation, breaking down collagen and elastin in the skin. As a result, wrinkles begin to form.
Luckily, there are lifestyle changes you can make to offset glycation. Cutting back on sugar can make a big difference. There are also several skin care products that prevent the breakdown of collagen and elastin while protecting your complexion.
Supplamine, MEG 21's patented formula, is designed to combat the effect of sugar molecules on the skin. MEG 21 Smooth Radiance Face Treatment uses Supplamine to reduce the damage caused by the glycation process and defend your skin against inflammation, free radicals and other environmental stressors. MEG 21 Anti-Oxidant Boost combines Supplamine, Indian Gooseberry and grape seed extract to fight glycation, free radicals and oxidative stress.
Blueberry extract inhibits the glycation process and helps prevent the breakdown of healthy collagen. SkinCeuticals A.G.E. Interrupter uses blueberry extract to prevent AGE formation and reverse damage, improving skin firmness and elasticity. SkinCeuticals A.G.E. Eye Complex contains blueberry extract to prevent the breakdown of collagen and elastin.
Carnosine is a protein builder that helps prevent the glycation process. dr. brandt Collagen Booster contains carnosine as well as alistin, a molecule that keeps collagen fibers from getting brittle when exposed to free radicals. PRESCRIBEDsolutions Cream - No Sugar pairs carnosine with powerful ingredients like photosomes, roxisomes, ultrasomes and shea butter to hydrate skin and repair damage.
How will you protect your skin from too much sugar? Share with us in the comments.
Shop This Blog
- Protects against environmental damage
- Diminishes fine lines
- Suitable for all skin types
- Defends against free radical damage
- Creates a silky soft texture
- Adds a soft, radiant glow
- Stimulates collagen and elastin
- Restores lost moisture
- Protects the natural barrier
- Minimizes crow's feet
- Improves dark under-eye circles in 12 weeks
- Diminishes puffiness
- Stimulates collagen production
- Reduces wrinkles
- Promotes younger-looking skin
- Revitalizes damaged skin
- Provides essential hydration
- Improves elasticity
Dr. David A. Bushore's Favorite Uses for FixMySkin Healing Balms
What's Causing Your Dry Skin?


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Don't miss the Etsy Craft Party this Friday, June 10 from 7–9 p.m. at Oil & Cotton.
Anyone who knows crafts knows Etsy, and this year marks the sixth anniversary of the Brooklyn-based, online craft marketplace. The free event will include "craftivities" like landscape necklaces, leather cuffs, paper teepees and a community collage as well as spinning demonstrations by local artists, a community weaving project and a screening of the documentary "Handmade Nation: The Rise of DIY, Art, Craft and Design."
The event will also raise money toward scholarships for kids in the Oak Cliff neighborhood who wish to attend art classes or camps at Oil & Cotton.
Click to sign up for the Advocate's weekly news digest and be the first to know what's happening in Oak Cliff.


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Kanya M Model
TanyaClarkModel Female Perth, Western Australia, Australia
My MM URL: http://www.modelmayhem.com/tanyaclark
Mayhem # 298021
About Me
Hello my name is Tanya Clark, I am 21 years old and based in Perth.
I am interested in all types of modelling and am open to any ideas. I will do TFP or TFCD if i am comfortable with the photographers work.
I will not do anymore implied nude or nude shoots due to personal reasons, i hope you understand
I Look forward to hearing from all MMers
Have you worked with TanyaClark? Add Credits for TanyaClark! >>
Credit Notes
MMer's i have worked with:
Kelvin Chong (photographer)
Ever After Photography (photographer)
Rach C (Model)
Glen Earnshaw (Photographer)
David Broadway (Photographer)
Anne Ford (Photographer)
Marita Bird Photography (Photographer)
Elsie (Make-up Artist)
Wicked Witch Productions (MM #247718)
Percy Ortiz (Verve Photography) (MM #289638)
Sophie EMS (Make-up Artist)
Kanya M Model
Percho Photographer
Ever After Photography Photographer
Mike Duffy Photographer
Shoot the Wicked Witch Photographer
proof27 Photographer
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With their delicate and favorable taste snow crab legs steel the spotlight of any meal i which they appear. When preparing side dishes to accent crab legs, less is more. By pairing crab with downplayed side dishes you can really highlight the simplicity of the naturally sweet, rich flavor of snow crab legs.
Potatoes are almost always an excellent side dish; baked, roasted or mashed, any way you slice it, potatoes can complement your crab legs flawlessly.
Roasted red potatoes offer a change from the usual baked or mashed russet potatoes. Preheat the oven to 350 degrees Fahrenheit. Dice your potatoes (1 1/2 lbs. small, new, red potatoes (about 15), scrubbed and dried ). In a large bowl, mix 4 to 6 cloves crushed garlic, 1/4 cup extra virgin olive oil and rosemary (to taste); add the potatoes and toss well. Transfer the potatoes to a shallow, baking pan and roast until potatoes are tender when tested with a fork, about 30 to 45 minutes.
Corn on the cob works nicely as a side dish for crab legs. On your stove, place shucked corn in a large pot and cover with cold water. Add a pinch of sugar to keep corn tender. Bring pot to a boil, when water comes to a rapid boil, the corn is finished. Serve with butter and a pinch of salt.
A side salad is a fast, easy way to incorporate a variety of vegetables into a meal. It also offsets the richness of snow crab legs. You can prepare a salad with any fresh or seasonal ingredients. Begin with a base of greens, baby spinach, romaine lettuce, assorted field greens or arugula, for example, and build from there with your favorite vegetables.
Never underestimate the elegant simplicity of an artisan bread. A whole eat-with-your-hands meal is an appealing concept, and a dinner roll or hefty piece of crusty bread perfectly offsets buttery, sweet crab legs.
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- Photo Credit Jeffrey Hamilton/Lifesize/Getty Images
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The hotel has a restaurant, bar, conference room, coffee shop and a total of 194 guest rooms. Further facilities available to guests include a 24-hour reception, lift access, a caf�, WLAN Internet access (fees apply), room service, a laundry service (fees apply) and a car park and bicycle hire service.
The city hotel is located in the suburbs of Weimar, around a 10-minute drive away from the Weimar city centre. Only 1 km from the A4 motorway, situated between Jena and Erfurt, the business hotel offers an excellent connections to the national road network and to the trade-fair city of Erfurt.
Anyone staying in one of the lavishly furnished standard rooms is sure to find the harmony and relaxation needed during a stay in a hotel. All the rooms are equipped with an en suite bathroom with shower/WC and hairdryer, a direct dial telephone, minibar, radio and satellite TV.
Guests may take a dip in the indoor swimming pool or relax in the sauna or steam room. Massages and spa treatments are offered for an additional fee.
A breakfast buffet is served each morning and � la carte options are available for dinner.
American Express, Diners Club, MasterCard and VISA are accepted as methods of payment.
Arriving on the A4 Bad Hersfeld-Eisenach-Dresden motorway, exit at Weimar. The hotel is situated 1 km along the B85 in the direction of Rudolstadt, at the roundabout on the right-hand side.
Under section 4 of the Statutes of the City of Weimar, the hotel is required to collect a culture promotion fee of EUR 2.00 per room per night singleroom and EUR 1.50 per person per night. This charge will be passed on directly to Weimar City Council.
Room Facilities:
Direct dial telephone
Satellite cable TV


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Eacus is a weather god worshipped in Iberian Spain. He is known from the area of Castile and was syncretised with the local Roman deity Jupiter Solutorius.
- Michael Jordon, Encyclopedia of Gods, Kyle Cathie Limited, 2002
|This page uses content from the English Wikipedia. The original article was at Eacus (god). The list of authors can be seen in the page history.


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Series: Phosphate Deposits of the World Volume: 3
450 pages, Illus, tabs, maps
It has recently been recognised that marine phosphorites, the principal raw material for phosphatic fertilizers, do not occur uniformly through time and space. The origin of these unusual sedimentary rocks appears to be related mainly to marine biological productivity, often associated with upwelling currents during certain intervals of geological time. This book examines the environmental setting and resulting phosphorites which formed during the Miocene, one of the major and most recent phosphogenic periods throughout the geologic record. In addition, an oceanographic perspective is given by investigations of modern oceanic environments where phosphorites are presently forming. Together, the geologic and marine approaches provide a complete outlook on this important mineral resource. This book is the third of four planned reference volumes which together will cover the achievements of the International Geological Correlation Programme Project 156 (Phosphorites) during the ten years of the project's existence.
This comprehensive and authoritative collection of articles neatly supplements its companion volumes (1 and 2) and is an essential reference work for those interested in phosphate deposits and mechanisms of phosphogensis. Geological Magazine "For anyone working in the field, though, it will be an indispensable source of information, both in the text and in the extensive references which accompany each of the 32 chapters." William R. Green, Geophysics
There are currently no reviews for this product. Be the first to review this product!


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We all have our own pet reasons why we hate to fly, but I have a confession – I simply love to fly! I love everything about flying: the cramped seats, the safety instructions, the often indifferent air crew (if we're talking Air India; other airline stewards tend to be gushingly cheerful)… everything! Here are the many reasons why I love airplanes and love flying:
The soaring anticipation
Its travel time! I see those beautiful, fluffy clouds below me… What's not to like! Whether it's a familiar place or a exotic new place you're visiting, there is the anticipation of the trip, the joy of soaring above the clouds…. I love the takeoffs – that surge of speed just before liftoff and the landings too!
Appreciation of the alternative
Traveling the same distance by bus would be an unspeakable purgatory. If its train you have to think of ways to keep yourself sane for many hours; if you're traveling with kids you have to arm yourself with an extra bag of items to keep the blighters entertained. As for the train loos… less said the better!
I can switch off my phone
I can switch off my phone; I have to, they told me to! I can be off the radar and never have to apologise to mother, friend, acquaintance! And I can still play games on my phone! Yay for my phone's Flight Mode!
The food
Yes l love the food as well! People may claim that the small portions on plastic trays taste terrible but I love airline food. I love how everything is packed nicely, that there's a salad, a side dish and a sweet. I love that it's free; I even love the vile tasting tea and coffee they serve onboard.
The earphones
It's a legit excuse to tune out importunate fellow passengers who want to chat or share. Smile politely, stuff in those earphones and get on with the old Salman Khan film that you've been meaning to watch again.
The air-pockets
Whoo! The bottom just fell out of my stomach! And I loved it! It's the same thrill I get from a boat ride in choppy water, a giant-wheel, a merry-go-round…. There is the added thrill of never knowing when the next air-pocket will happen.
In-flight entertainment
It keeps the children out of my hair – reliably, there is a Tom & Jerry or Disney feature on. So what if my own choice of entertainment is a tossup between an old SRK film that I never wanted to watch and some old English film that I'd already seen?
The Dreamliner
Air India has the Dreamliner and on my recent flight from Delhi to Kolkata and back, my family and I discovered its various joys – windows that dimmed at the press of a button, great leg space, huge overhead bins, a gaming console and excellent choice of in-flight entertainment that you can navigate yourself. I admit to a twinge of envious heartburn when passing through the first class cabin, but that was short-lived. Even the economy class of the Dreamliner is vastly superior to other aircraft.
The miniature loo
You cannot swing a cat in there, but it's all a marvel of the miniature: the pot, the sink, the folding door, the rubbish bin, the mirror. It's all there, tucked into its respective tight little corner. And that vacuum flush – admit it… its fascinating!
Its massive, it's classy, it has great shopping and a really decent food court. If you transit via the international terminal the shopping is even better! The terminal is so big you can enjoy a good, brisk morning or evening walk even! Charge your phone, take a restful nap on the loungers, enjoy looking at the other travelers or simply take in what's happening on tarmac. There is a lot to help you pass the time of day when you're at Delhi's T3 terminal. Somehow flight delays don't bother me as much when I'm lodged within the climate controlled interiors of T3. And did mention, I simply love flying?
By – Reena Daruwalla
See also
Men! 10 Things Women Hate about You
14 Essential Sensory Experiences of the Indian Summer
Photos courtesy – Air India, Tumblr, Wikipedia, Giphy


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In Feb this year, UK-based Vicon made the technology dubbed "Vicon Revue" available to researchers who study Alzheimer's disease and other conditions that affect short-term memory loss. Now, in August, Vicon will release the next-generation camera, the Revue 3MP.
The camera, which is about the size of a Post-It note, is worn on a cord around the neck and unlike ordinary digital cameras or camera phones, the Revue doesn't have a viewfinder or a display - it's equipped with a wide-angle, "fish-eye" lens that captures nearly everything in the wearer's field of vision. The camera can be set to a timer. But, more often than not, it's set to capture an image each time it senses a change in motion, light or temperature. In either case, images are captured without the user having to stop and take a photo themselves.
The end result is a series of hundreds, thousands, even tens of thousands of photos that are recorded on the device's internal memory and later loaded onto a computer. When reviewed, the photos act as a visual diary as shown in the video below.
The theory goes like this: because photos are taken in automated, fragmented way, and are taken from the users' point of view, looking back on the photos later can trigger memories in ways that ordinary photos can't.
Tests have shown that Revue photos enabled users to retrieve memories that would otherwise be lost. And the memories remained in their minds for weeks and months afterward.
In addition to aiding memory loss, Vicon points to other potential uses, including:
- Monitoring exercise, medication, food and alcohol intake
- Security, law enforcement, and military applications
- Emergency services
- Teaching and school projects
- Documentary making and art projects
- Market research


text: They recycle weapons and try to survive in this era, do they? GalleryEdit Retrieved from "http://ravaged.wikia.com/wiki/Scavengers?oldid=4137" Ad blocker interference detected! Wikia is a free-to-use site that makes money from advertising. We have a modified experience for viewers using ad blockers Wikia is not accessible if you've made further modifications. Remove the custom ad blocker rule(s) and the page will load as expected. Categories: Factions Add category Cancel Save


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Most Helpful Girl
Yea it's kind of a pain.00|00|0
Have an opinion?
The only opinion from girls was selected the Most Helpful Opinion, but you can still contribute by sharing an opinion!
You can filter your feed only for questions:
- tap on the "All Posts" drop down menu and select "Questions"
- click "Remember"
This way, you will only see Questions on each of your visits to the feed.
If you want to see "only questions from the topics you follow" you can also calick on the Topics icon (books image) which will turn to Green.
how are you searching for new questions?
oh yes, that is the new way.
You cannot undo this action. The opinion owner is going to be notified and earn 7 XPER points.


text:
or Register to get access
The Bangkok Medical Journal is the official journal of the Bangkok Hospital Group. The Journal publishes original articles on all aspects both clinical and experimental.
The Editors-in-Chief of The Bangkok Medical Journal invite manuscripts in all areas of medical research. As a general guide, manuscripts will be considered for publication if they contribute significant new findings to the field.
- Predicting and preventing cardiovascular events in asymptomatic cases: The 10-year prospective study.
- 60-day survival rate under treatment of Acute Type A Aortic Dissection by Transapical Aortic Cannulation Technique.
- Midterm results of surgical intramyocardial implantation of autologous angiogenic cell precursors for cardiomyopathy
- Comparison of Epidural Steroid Injection between L5-S1 Retrodiscal Technique and S1 Transforaminal Technique in L5-S1 Spinal Stenosis with S1 Radicular Pain.


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4U Cafe
Oklahoma City, OK 73108
4U Cafe is probably one of Oklahoma City's best kept secrets when it comes to delicious food. Located inside the H&H...Learn More
4U Cafe is probably one of Oklahoma City's best kept secrets when it comes to delicious food. Located inside the H&H...Learn More
Located in downtown Oklahoma City, The Garage has made a name for itself due to the tasty burgers and delicious drinks...Learn More
Warm up on chilly days with toasted smores procured from the Snow S'more Food Truck found throughout Oklahoma City....Learn More
Pho'ever in Oklahoma City offers traditional Vietnamese cuisine. Begin with an appetizer like crispy spring rolls, crab...Learn More
The Parrot Steakhouse & Grill is one of Grand Lake's fastest growing hot spots. With a laid back, tropical...Learn More
For tasty Greek food, look no further than Anna's Famous Gyros in Oklahoma City. This restaurant serves gyros topped...Learn More
Reb Lobster in Oklahoma City is a casual seafood restaurant known for its fresh fish, shrimp, scallops and, of course,...Learn More
Head to Smashburger in Oklahoma City for a huge variety of burgers, chicken, sides and salads made fresh to order....Learn More
City Bites in Oklahoma City features sandwiches, wraps, baked potatoes, salads and cookies. A long-time local...Learn More
Load up on a burger with a twist after waiting in line at the Wicked Hangry food truck. Once you stumble across this...Learn More


text:
- Description
Lounge outdoors in pure relaxation with this 3-piece lounger set that features two adjustable loungers with a plush cushion for full body support and a small side table that great for holding drinks and snacks. Select from an weather-resistant and durable aluminum and resin wicker furnishings in Gray Blue and tan.Includes
1 Adjustable LoungerDimensions
30"L x 84"W x 22"H
- Additional Information
Additional Information
SKU 14791577 MPN P50164 GTIN UPC 742169012745 Brand Poundex Collection N/A Assemble Length N/A Assemble Width N/A Assemble Height N/A Assembly Required Yes Material Wicker Finish Other Styles Contemporary Shipping Time 1-2 Weeks Free Shipping Yes
- Reviews
Disclaimer: Pictures displayed may include optional products not included in the price. Computer monitors often display color variations. Color swatches are shown if alternative colors are available. Please call us or email us if you have any questions!


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Google Analytics is a service offered by Google that generates detailed statistics about a website's traffic and traffic sources and measures conversions and sales. Google Analytics can track visitors from all referrers, including search engines and social networks, direct visits and referring sites. It also displays advertisin...
Rambler's site rating system and counter from Russia.
Yandex is an internet technologies company that operates in Russia, CIS and Turkey. It is the largest Russian and fourth-largest world internet search engine. Yandex is an acronym for the phrase Yet Another Indexer. As of March 2013, Yandex had about 61% of the Russian search market (source: LiveInternet.ru). Yandex's miss...
A family of standard web feed formats used to publish frequently updated information like blog entries, news headlines, audio and video.
Websites using some type of Facebook technology.
Facebook Connect allow users to connect their Facebook identity, friends and, privacy to any website. Facebook Connect is Facebook's first attempt to allow access to Facebook user data outside of Facebook itself. The company is describing it as giving third party applications access to much of the same data as Facebook applicat...
jQuery: The Write Less, Do More, JavaScript Library.
A lightweight and modular front-end framework for developing fast and powerful web interfaces.
Fast, light, complete: 70+ jQuery-based UI widgets in one powerful toolset.
Google Tag Manager makes it easy for marketers to add and update website tags including analytics, remarketing, and more.
This site uses the viewport meta tag which means the content may be optimized for mobile content.
nginx [engine x] is a HTTP server and mail proxy server written by Igor Sysoev.
The DOCTYPE is a required preamble for HTML5 websites.
Allows a website to define how a page is rendered in Internet Explorer 8, allowing a website to decide to use IE7 style rendering over IE8 rendering.
Websites using https protocol.
Open graph type entity tag
Open graph url entity tag
Open graph description entity tag
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The Open Graph protocol enables any web page to become a rich object in a social graph, a open protocol supported by Facebook
Open graph image entity tag
Open graph title entity tag
Google's hosted library for web fonts. Allows websites to choose and use fonts from a free, wide variety of fonts.
The http-equiv attribute provides an HTTP header for the information/value of the content attribute. The http-equiv attribute can be used to simulate an HTTP response header.
Wesites using favicon rel tag
This tag indicates websites that a chrome application.
UTF-8 (8-bit UCS/Unicode Transformation Format) is a variable-length character encoding for Unicode. It is the preferred encoding for web pages.


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Keep kids learning
Worried your kid forgets everything they've learnt when not at school? Here's how to keep their brain sharp. more
Last revised: Wednesday, 29 October 2008
This article contains general information only and is not intended to replace advice from a qualified health professional.
Enter your child's birthday


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Southern California High Tech Event Calendar
|View By:
|View By:
|CommNexus Military SIG
|Date: June 11, 2009
|Location:San Diego
|CommNexus Military SIG Presents: Field Trip To The Tactical Training Group, Pacific. The mission at TACTRAGRUPAC is to provide advanced tactical training to warriors in order to improve their proficiency in war fighting and joint operations. TACRAGRUPAC provides traditional school-house training, in-house war gaming, and Fleet Synthetic Training (FST), which will be highlighted during the tour. See http://www.commnexus.org
|More information: http://www.commnexus.org
|Download to Calendar


text:
Obama-dodging Democrat's excuse gets funnier by the day
Filed Under Politics | 1 Comment
I'm just loving the excuses Obama-supporting Dems are coming up with to explain why Obama can't be anywhere near them ("political survival" not among the excuses because it's too honest).
This one's from Sen. Jeanne Shaheen who is trying to salvage her re-election in New Hampshire:
Shaheen: Obama's Too "Busy" to Campaign For Me via @danpdoherty http://t.co/rWyrhfRXTw
— Raffi Williams (@Raffiwilliams) October 24, 2014
Obama has greater priorities than coming to N.H. to help save the Senate for the Dems?
Dallas Nurse Nina Pham beats #Ebola, gets a hug from Pres. Obama. @CNN's @ErinBurnett reports: http://t.co/7JAGsN2z00 pic.twitter.com/nSc9b5vCm5
— OutFrontCNN (@OutFrontCNN) October 25, 2014
And today:
67° and sunny in DC. Pres Obama just arrived at Fort Belvoir for a round of golf.
— Mark Knoller (@markknoller) October 25, 2014
"Too busy" is believable… as long as you also believe that Obamacare is working and the stimulus seeded job growth.
(h/t Twitchy)
One Response to "Obama-dodging Democrat's excuse gets funnier by the day"
Reflective material on
July 13th, 2015 7:34 am
Just become alert to your blog via Google, and found that it's truly informative.
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Everyone is going on a Virgin Holiday
Who we deceived, we know well that they nothing else placed them only for the photography and, disloyal guerrillas. Of positioning for the short while. Bad for me!
well, it surely did work.
but I think this idea was on everyone's mind more or less for such a long time already, it's not even interesting when finally someone does it...
*the best skate/snow/surfing videos and pictures.
*updated daily!
AdArena: Sex Sells
[edited by admin for foul language], virgin [edited by admin for foul language] is a nice way to [edited by admin for foul language].
makes me wanna [edited by admin for foul language] right away!
It's not the most amazing idea but I think it works within its context.
*&%#, I think we have something here, well, for today atleast... This definitely works, not great but interesting. Think of it this way, you walk past there day in - day out, then one day, KABLAM!!! You see branded travel bags everywhere. Kinda cool considering how boring those lifeless statues are... Not new but in this cotext, rather unique idea I'd say...
Not even twenty tongue rings could (beep) with my speech...
:: Put your ears against the ground so i can walk over what you heard::
Man I'm tired of this "[edited by admin for foul language]" gimp, who just decided to bravely put his Tarzen knickers on today and annoy the *&%# "[edited by admin for foul language]" F off mate, go find another hobby!
Not even twenty tongue rings could (beep) with my speech...
:: Put your ears against the ground so i can walk over what you heard::
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How do I look?
How do I look?
Have an opinion?
have you ever seen an escaped clown from a circus? thats what u r
I thought it was funny and shows personality...
It was New Years!
i know..
Love it! :)
It is actually good - It is a pity about flash in the eyes
I should have asked only for girls...
You cannot undo this action. The opinion owner is going to be notified and earn 7 XPER points.


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A variant of the water Molecule H2O, but with two Hydrogen atoms (H) instead of just one.
Nature Edit
While used to Power Fusion Reactors this is because they are the richest sources of Deuterium naturally. Heavy Water is a fairly uncommon natural occurrence, though they can be created by water subjected to intense Gravity.


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Each year, Europol's European Cybercrime Centre (EC3) produces the Internet Organised Crime Threat Assessment (IOCTA), its flagship strategic report on ongoing developments and emerging threats in cybercrime — threats that impact governments, businesses and citizens in the EU.
There are three anti-cybercrime operational action plans under the European Multidisciplinary Platform against Criminal Threats (EMPACT) cycle. The IOCTA focuses on the crime areas that fall under EC3's mandate of Europol's EC3:
It also addresses other areas of criminality that directly impact, or operate in parallel with, the crime areas above, such as money laundering and social engineering. It draws on contributions from:
- experts at Europol
- law enforcement authorities both within and outside the EU
- partners in the private sector and academia.
Typically, the IOCTA will also highlight crime enablers that straddle more than one crime area and that require concerted and coordinated international law enforcement action, such as:
- malware
- bulletproof hosting
- illegal trading sites on darknets
- money muling and laundering services
- criminal communications online.
Other topics the IOCTA may cover include:
- big data
- the internet of things (IOT)
- how cybercrime is distributed
- debates around encryption
- legislation on cybercrime
- cybercrime and artificial intelligence (AI).
While there have been variations each is put together, the basic structure is fairly constant, and comprises the following elements:
- key findings in such areas as:
- the changing profiles of offenders
- partnerships with the private sector
- ransomware, malware and remote access tools (RATs)
- data beaches
- trends in payment fraud, such as card-not-present fraud
- key recommendations in the following areas:
- prevention through awareness-raising
- prevention through training and capacity-building
- partnerships
- investigation
- legislation
- suggested operational priorities within the aforementioned crime areas under EMPACT
- key findings, including on global trends
- general observations.
The IOCTA may also include word on operational successes in the year under review. Two examples will serve as illustrations. The first is a global operation against dark markets that were being run on The Onion Router (TOR) network. In the operation, which was coordinated by Europol, law enforcement agencies in the EU worked with their counterparts in the United States to bring down several marketplaces as part of a concerted international action.
The second example is a follow-on to successful operations against airline sector fraud: other areas of internet-facilitated payment card abuse were subsequently identified and addressed at the national, EU-wide and global levels, leading to a number of operational successes.


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Delivering High Quality Video over IP
Why Your Digital Video Service Must be Monitored
For years, network and service monitoring tools have been providing operations engineers with invaluable information for troubleshooting, diagnosis and problem resolution. With the introduction of new high bandwidth, real-time video services that stress IP network infrastructuremonitoring solutions become even more critical. Escalated end-user expectations for video quality—especially for HD—combined with the negative business impacts of delivering a poor quality service, are driving demand for higher quality and new video-focused monitoring solutions.
Impairments to video services can come from a wide variety of sources. Having not been designed for large volumes of real-time video traffic, "best effort" IP networks do not meet the quality requirements of today's digital video services. In addition, video architectures are becoming more complex and constant content manipulation from the content owner down to the end-user also adds additional corruption risk—encoding/transcoding, digital ad-insertion, splicing, statistical multiplexing, and up/down conversions are examples of such manipulations.
Click Here to Register & Download Symmetricom's "Delivering High Quality Video over IP"


text: Home Gallery Video Fruit of the Loom Fruit of the Loom Proves Its Boxers Won't Budge Invisible Pants Prove Fruit of the Loom Boxers Won't Budge CP+B Created Unusual Product Demo to Showcase Newly Redesigned, No-Ride Up Boxer Brief Published on Mar 27, 2015 Editor's Pick Fruit of the Loom wants to prove that its new boxer-briefs won't move -- even if you bust some crazy moves to '90s hip-hop while wearing them. A new spot out of Crispin Porter & Bogusky features employees at the "Fruit of the Loom Headquarters" testing out the newly designed no ride-up boxer briefs -- while wearing clear plastic pants so viewers can be absolutely certain that the underwear does not ride up. Who could argue with this empirical, scientific evidence? After three men in the plastic pants dance to Blackstreet's "No Diggity," another employee measures the boxer length to confirm that there was no boxer shifting while the men were expressing themselves through kicks, twists and jumps. Created by CP+B and directed by Martin Granger, the "Plastic Pants" campaign announces Fruit of the Loom's most popular boxer brief style redesign. This is the first installment of an effort that will provide "a peek behind the cotton curtain at the passion that guides the design and construction of every garment," CP+B said in a statement. Changes to Fruit of the Loom's most popular boxer-brief style include a softer waistband, a redesigned cut and longer legs so the boxers stay put. Last December, a Fruit of the Loom spot with Crispin Porter + Bogusky explored the etiquette of giving underwear as a gift. Rate this Ad You must be registered to rate the ad. Please Login or Register Now About CreditsDateMar 27, 2015Agency:CP+B Chief Creative Officer:Ralph WatsonClient:Fruit of the LoomVP/Creative Director:Dave SteinkeVP/Creative Director:Allen RichardsonAssociate Creative Director:Mona HasanAssociate Creative Director:Nicholas BuckinghamVP/Director of Video Production:Kate HildebrandtIntegrated Video Producer:Annie TurlayIntegrated Jr Video Producer:Addison BornIntegrated Jr Video Producer:Shelby HawkinsonVP/SR. Business Affairs Manager:Rebecca WilliamsMusic Supervisor:Andy HammAssociate Planning Director:David BurgSenior COG:Allie ColeHispanic Consultant:Abel GonzalezAsset Producer:Eva HunterDirector of Photography:Eric SchmidtProduction Company:Moxie PicturesDirector:Martin GrangerExecutive Producer:Karol ZenoHead Of Production:Paula BensonProducer:Heidi SolteszEditorial Company:Hutch Co.Editor:Jim HutchinsFinishing/VFX:Method StudiosCreative Director:Claus HansenSenior Flame Artist:Wensen HoExecutive Producer:Robert OwensProducer:Paula JimenezAudio Finishing:Lime StudiosEngineer:Mark MeyuhasAssistant Engineer:Matt MillerExecutive Producer:Jessica LockeExecutive Producer:Susie BoyajanColor Finishing:CO3 Colorist:Stefan SonnenfeldExecutive Producer:Rhubie JovanovSee more credits Latest Creativity News on Ad Age Gallegos United Has a New CCO, Arnold Hires Alfson, Low Joins Ogilvy Beijing 'I Have a Huge Idea:' Wyclef Jean Wants to Work With Brands BBH New York Rebuilds Leadership Team With New CEO, CCO and Chairman Related work Fruit of the Loom: The Most Epic Story Ever Told Crispin Porter + Bogusky Fruit of the Loom: Frut CP+B Fruit of the Loom: Dressing Room CP+B


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|Page (1) of 1 - 05/08/12
|email article
|print page
W. R. MEADOWS Goes Mobile: Website Now Optimized for Mobile Devices(May 08, 2012)
Hampshire, IL (PRWEB) May 08, 2012
W. R. MEADOWS, a leader in the construction products industry for more than 85 years, recently optimized its website for mobile viewing on iPhone, iPad, and Android devices.
Designed to load quickly on 3G/4G speeds, W. R. MEADOWS mobile site eases architects, engineers, and contractors searches for product information, data sheets, MSDS, and guide specs while traveling or on the jobsite.
The website will automatically detect use on an iPhone, iPad, or Android device and instantaneously display the mobile-friendly version. The re-formatted content is easy to view and fast loading, making the website easy to navigate for visitors on the go.
The mobile homepage provides easy access to the full W. R. MEADOWS product directory, site search, data sheets, MSDS, guide specs, application details, project profiles, and training videos.
In addition, the new mobile-friendly website makes it easy to share content via email or social networks. Users also have the option to switch to the standard PC version of site at any time.
Visit http://www.wrmeadows.com on your iPhone, iPad, or Android device to check out the mobile-friendly version.
W. R. MEADOWS, INC. designs, manufactures, and markets high quality building materials for todays construction professionals. Products are sold through our authorized distribution network. We are a family-owned and operated company focusing on product quality, business integrity, and outstanding service since our founding in 1926.
We remain committed to producing environmentally-friendly products and systems that meet or exceed the latest regulations. From highway construction and repair, building construction and restoration, to waterproofing/vapor barrier/air barrier products and more, weve been satisfying the needs of the public and private sector of the building construction industry for over 85 years.
Read the full story at http://www.prweb.com/releases/wrmeadows/mobile-site/prweb9474008.htm.
Page: 1
Related Keywords:design and engineering, fishing industry, construction and property, heavy construction, house building, cinema industry, radio industry, television industry, music industry, building material, process industry, computing and information technology, satellite technology, wireless technology, science and technology, technology (general), identification technology, agricultural research and technology, economy, business and finance, financial and business service, business enterprises, online, marketing, business (general), computer crime, computer crime, computing and information technology, satellite technology,


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How SCIAF began
The story of SCIAF is an inspiring journey. Three men played a key role in our history when they helped launch the charity with the bishops of Scotland back in 1965.
The timing could not have been better for SCIAF to write our opening chapters, as it was an extremely important time in the history of the church. The second Vatican council (Vatican 2) was taking place.
Around this same time, the Catholic Church issued several papers calling for people to make a stand for those impacted by the injustice of hunger and poverty in the developing world. These papers inspired the Scottish Bishops to answer the call and SCIAF was set up.
We may have started off small, but with the help of fantastic supporters like you we have come so far. Thanks to you, SCIAF has been able to save the lives of millions of people in desperate need across Africa, Asia and Latin America. These people are from a diverse range of religious and ethnic backgrounds, but they have something in common....they all need our help.


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The University of California has admitted more Latino students than white students as freshmen for the first time in the system's 146-year history, according to figures released Friday.
About 29 percent of freshmen admitted this fall to one of the UC system's nine campuses were Latino. About 27 percent were white. Asian students still made up the highest percentage of admitted students, 36 percent. These figures include only in-state admissions.
The system admitted 61,120 incoming freshmen, also a record high.
Many educators are hailing the record number of Latino admissions as a sign that one of the nation's most prestigious public university systems continues to widen its accessibility to students.
"The ongoing change in California's demographics is reflective in these numbers," said Dianne Klein, a spokeswoman with the UC system. "There has previously been a misconception that UC is too expensive and not a good fit for every student. These figures show this thinking is changing."
In California, more than half of public school students are Latino.
Klein said UC campuses have worked hard in recent years to reach out to high schools that have been historically underserved by the system. About 43 percent of admitted freshmen identified themselves as the first in their families to attend college. About 37 percent come from low-income families.
"We need a populace that reflects California's residents," she said.
The system admitted 1,031 more freshmen than in the previous year, an increase of about 2 percent. The admission rate for the system was about 61 percent, compared to 60 percent last year. But admission to the system's most coveted campuses remains elusive.
UCLA offered a spot to 9,128 incoming freshmen, or about 16 percent of all applicants. UC Irvine offered admission to 17,396 freshmen, or 33 percent of applicants.
Both campuses offered fewer admissions spots compared to last year, a drop of 4 percent at UCLA and a drop of 11 percent at UC Irvine.
Klein said enrollment targets are set by individual campuses. The drop in admissions doesn't mean schools are cutting their enrollment, she said. These campuses offered a higher rate of admissions in previous years, so they're likely adjusting their figures this year to compensate, she said.
UCLA received 86,521 applications from high school seniors for admission, the most of any UC campus, and among the highest figures for all universities in the country.
"UCLA is becoming a destination point. You can see by these numbers that many families know the value of a UCLA education," said Youlonda Copeland-Morgan, the school's vice chancellor for enrollment management.
"Our trajectory shows that UCLA will receive even more applicants in coming years," she said.
Admitted freshmen have until May 1 to decide if they will accept their invitation to enroll.
Contact the writer: firstname.lastname@example.com


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Making this fun cake next week, but I have a couple questions. First, I'm planning to stack several 6 inch round cakes to get the proper height. If I'm stacking higher than 4 inches (a normal tier) do I need to dowel and rod the extra tiers on top?
Also, If anyone has tips for the rim of the hat, that would be amazing! I'm thinking gumpaste should do the job with towels underneath scrunched up while it dries, but I'm not positive.
I would put the support on the bottom two layers to keep it from collapsing on itself, try the sps system and cover the whole thing then you wouldn't have to worry about it leaning. As for the brim the towels sound good I just would cover them with plastic wrap to keep the fuzzies away.
Get a cheap sombrero at a party store. Cut the head part off and use the brim as a form for gumpaste.
At least that's what I'd do.
I would do exactly what jammjenks said
Get a cheap sombrero at a party store. Cut the head part off and use the brim as a form for gumpaste.
At least that's what I'd do.
Good idea!!!
It looks like the cake in the picture has something black giving shape to the brim. I guess you could always do it that way too.
It looks like the cake in the picture has something black giving shape to the brim. I guess you could always do it that way too.
It does have something black under there, I remember seeing this cake before, but I would do what jammjenks suggested to kick it up a few notches, thats actually what I do now for baseball caps, and other hats, including flowers, I goto Michaels and buy a flower I want to recreate, take it apart and use the petals to dry my gum paste on.
Now that you mention it, it does look like there is something black underneath it. That hat idea is a really good one - I'll give that a try for sure. I guess I would cover the whole rim piece in one piece of fondant with a 6inch round circle cut out of the middle. When it's dry slip it over my fondant covered middle?
A little nervous about the carving because I haven't had good luck in the past. Got to remember to take a small amount off at a time and slow down
Thanks CCers!
It looks like the decorator used black fondant as "risers" underneath the brim to give the different crease effects in the brim while adding a 3 dimensional look at the same time. I would roll out the brim in a whole circle, place the black fondant risers underneath to lift, decorate and let air dry right on the cake board. Once you have stacked and covered, transfer right to the middle of your brim and add a nice border where the two pieces meet.
Hope that helps & good luck.
P.S. - I had to do a sombrero for an engagement party enough to feed about 100 guest so my brim had to be made out of cake to accommodate the numbers.


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When your arrive, just tell Security you're going to lunch on the 2nd floor. Feel free to bring your lunch or purchase something from the cafeteria before hand. To ensure the meeting's success, please abstain from anything anything noisy like potato chips, granola bars, or soup (if you slurp).
Conference rooms 2A-2C are on the 2nd floor next to the cafeteria. Our meetings will be held in one of them. The Toastmasters banner will appear just outside the door. Please come in!
Meetup members, Log in
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text:
Mumintrollet (Moomintroll) was a Swedish television series from Finland, released in 1969, based on the Moomin books by Tove Jansson. It was written by Tove and her brother Lars Jansson and was directed by Vivica Bandler.
The series featured live actors dressed in Moomin costumes. It is infamous for having the actors portraying the Moomin family take off their costume heads a bit into the series.
13 25-minute episodes were produced.
- Den lyckliga dalen (The Happy Valley)
- Av med näsan (Off With Your Nose)
- Fjärilar och hovningar (Butterflies and Courts)
- Guld och sammet (Gold and Velvet)
- Menuett och spaghetti (Minuet and Spaghetti)
- Rubiner och byxknappar (Rubies and Buttons)
- Parad och trolleri (Parade and Wizardry)
- Kungen kommer! (The King is Coming!)
- Kungen blir osynlig (The King becomes Invisible)
- Kungen flyger (The King Flies)
- Troll och teater (Trolls and Theatre)
- Rampfeber (Stage Fright)
- Generalrepetition (Dress Rehearsal)
- Nils Brandt - Muminpappan (Moominpappa)
- Birgitta Ulfsson - Muminmamman (Moominmamma)
- Lasse Pöysti - Mumintrollet (Moomintroll)
- Gunvor Sandqvist - Misan (Misabel)
- Gustav Viklund - Rådd-djuret (The Muddler)
- Elina Salo - Lilla My (Little My)
- Lisa Bergström - Filifjonkan (Fillyjonk)
- Gösta Ekman - Kungen (The King)
- Marianne Stjernqvist - Fru Karlson (Mrs. Karlson)
- Roland Hedlund - Kuriren (The Courier)
- Bert-Åke Warg - Hovdetektiven (The Court Detective)
- Jonny Eriksson - Vakten (The Guard)
- Hunden Grace - Hunden Ynk (Sorry-oo)


text:
Clue: "Other" category: Abbr.
We have 1 answer for the clue "Other" category: Abbr.. See the results below.
Possible Answers:
Related Clues:
- Etc. category
- Catalogue abbr.
- Odds and ends: Abbr.
- Catchall category: Abbr.
- Sundry: Abbr.
- Common file name
- Catchall: Abbr.
- Junk drawer abbr.
- Catchall abbr.
- Other: Abbr.
Last Seen In:
- New York Times - September 03, 2001
Found an answer for the clue "Other" category: Abbr. that we don't have? Then please submit it to us so we can make the clue database even better!


text:
Automated Patch Clamp offers a high-throughput variant of the "gold-standard" method of cell-based electrophysiology.
Axiogenesis' Cor.4U® human iPS cell-derived cardiomyocytes are a highly standardised cardiomyocyte preparation, resulting in excellent success rates and high quality of data. Moreover, due to their primary-like phenotype, Cor.4U® cardiomyocytes can be used for recording of action potentials using the current clamp mode.
Unique features:
- High-throughuput functional cardiomyocyte ion channel assay
- Highly standardized cell model for excellent success rates and data quality
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text:
Skeleton Key Fingerless Gloves by Simone Van Iderstine
Welcome! You are browsing as a guestWould you like to see 21 projects made from this pattern and much more? create a free account What am I missing?
Skeleton Key Fingerless Gloves
This pattern is available for $6.00 USD
buy it now or visit pattern website
buy it now or visit pattern website
For more information, see: http://sandandskycreations.com/blog/products-page/fi...


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- shrine
- I. noun Etymology: Middle English, from Old English scrīn, from Latin scrinium case, chest Date: before 12th century 1. a. a case, box, or receptacle; especially one in which sacred relics (as the bones of a saint) are deposited b. a place in which devotion is paid to a saint or deity ; sanctuary c. a niche containing a religious image 2. a receptacle (as a tomb) for the dead 3. a place or object hallowed by its associations II. transitive verb (shrined; shrining) Date: 14th century enshrine
New Collegiate Dictionary. 2001.


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I'm so confused. If someone could give me some guidance I sure would appreciate it.
I have found a commercial kitchen and the inspector is saying he is waiting for me to get my licenses.
I don't know where to start. I've filed my ficticious name, I have my FEIN, now what? Who do I contact to get a business license?
I will be baking in Winter Park which is in Orange County, however I live in Polk county. I know I need a occupational license but for which county? And since I could be delivering cakes to several counties, how does that play out?
you do everything in the county where you will be working (cooking) - not where you live and I don't think it matters where you deliver (I don't think). You go to the tax assessors office (in St Aug - you go to the same place that you get your vehicle tag) to get your business license and then you need to get your food handlers license (safeserve).
I hope that helped....
Yes, thank you for that info. With the wealth of info on the web I could not find out but once again a CC pulls through.
Many thanks.
You are so very welcome - the state of florida does NOT make it easy!!
Echooo3, I live in Polk County too and am going through the same thing. Is Winter Park the closest you are finding anything?


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