text:
Fathers, be good to your daughters
Daughters will love like you do
Girls become lovers who turn into mothers
So mothers, be good to your daughters too
A Duncan/Courtney Story
Written By Cereal-Killa
Beta Reader TrueJackVP408
Published on Saturday, June 25th, 2011
-All the Small Things-
Summary: When Courtney first told people that she and Duncan were having a child, they could only suspect that it was some type of sick, twisted joke.
Another turning point;
a fork stuck in the road
Time grabs you by the wrist;
directs you where to go
So make the best of this test
and don't ask why
It's not a question
but a lesson learned in time
It's something unpredictable
but in the end it's right.
I hope you had the time of your life.
So take the photographs
and still frames in your mind
Hang it on a shelf
In good health and good time
Tattoos of memories
and dead skin on trial
For what it's worth,
it was worth all the while
It's something unpredictable
but in the end it's right.
I hope you had the time of your life.
Chapter One: Unpredictable
Duncan knew Courtney for four years before they started sleeping together. That had to mean something.
I mean, Duncan could barely tolerate most girls for more than a month, much less four years, and that's four years without sex.
Let me repeat this.
Four. Years.
It wasn't like they went out or anything, but Duncan did want her in bed. Of course he wanted her in bed; she was hot, sexy, and her fiery personality was sure to be interesting for a romp in the sack.
But for four years, Duncan didn't let her know that he wanted her in more ways than one. He wanted her to be his, and it took another person trying to take her to make him come out and say it. When Alejandro showed up and asked her to go out with him, Duncan made a move. After four stupid, long ass years.
And then they slept together.
Duncan knew Courtney for six years before they started living together. That had to mean something.
Most of the time, once people start sleeping with each other more than once a week, when they end up sleeping over at the others house more often than not, they entertain the idea of moving in together. But for some reason that just never came up with Courtney.
Not until she had gotten her college degree and had then considered moving to Japan to study technology advancements. "How about you just move in with me, okay?"
Courtney had said yes and that she didn't like sushi anyway.
Duncan knew Courtney for seven years before he asked her to marry him. Obviously, this must mean something.
She'd been yelling and screaming at him and just in the worst of moods when Duncan pulled out the ring.
Her angry tears had kept falling and she had wiped a hand across her flushed face, "What the fuck is that?" She spat, her insides tumbling in anger and suspicion.
Duncan shrugged, but his eyes were bright and nervous like. "Will you marry me?" He remembered the whole down on one knee thing and hopped off of the couch, tripping a little but getting there. He gave her a small smile and hoped the ring was big enough, he'd been saving for five months now.
She cupped a hand over her mouth and nodded, a heart breaking smile in her eyes. "O-Okay! Yeah," she had stuttered shakily, falling into him and mumbling about what took him so long.
And that was what it felt like. For Duncan, everything took way too long to do. He could have had Courtney at any time he wanted but his dumb ass had made her wait. He couldn't stand himself for that and even though Courtney never admitted it, he was pretty sure she wondered sometimes why it took four, six, seven years to accomplish what other people did in two.
He hoped it seemed more romantic than stupid.
Duncan knew Courtney for nine years before she mentioned kids. He knew this meant something. But he didn't know exactly how much it meant.
They had been laughing about some movie on TV when Courtney brought them up. "Duncan, how do you feel about children?"
He didn't visibly stiffen, which she took as a good sign but she of course wasn't in tune to Duncan's inner self, who was in fact looking more and more like a solid block of ice as the seconds ticked by.
"They're cool." was his response.
Courtney narrowed her eyes. "They're cool?"
"That's what I said, right?"
"So do you want one?"
Ah, the moment of truth.
"At the moment?"
"Yes, Duncan, at this moment."'
"Are you going to get mad at me?"
"I have nothing to be mad about, Duncan, answer the question."
"…Are you sure?"
"Yes, Duncan. I'm sure."
"…Not at the moment, no, I don't want a kid."
"What the fuck is wrong with you?" Courtney yelled, and this time Duncan jumped and then the visible stiffening of his body was noticeable. "How can you even say that?"
Duncan pointed an accusing finger to go along with his scowl. "You said you wouldn't get mad!"
"So you don't want a kid?" Courtney yelled, anger, disappointment and total fear in her eyes that Duncan failed to notice at the moment.
"No, Princess, I don't. Not now." He said, calming his voice and trying to lower their conversational volume before the neighbors had another reason to hate them.
Courtney felt tears well up in her eyes. "Well, too bad, jackass, cause you're getting one!"
She growled ferociously. "That's right. I'm pregnant. Your sperm, your baby, so NOT your choice, ass wipe!" She kicked him in the shin before stomping up the stairs, two steps at a time.
Hissing in pain at the wound, he tried to focus on the hurt but his eyes were still left wide and emotionless due to the initial shock.
This had to mean something.
Oddly enough, Duncan did have a heart.
Courtney knew this for a fact, even if sometimes she had to question her sanity for believing it to be true. He was rather anti-social except when it came to flirting with women or acting like an ass. He was always setting things on fire on the back porch for entertainment, and he had yet to shed a tear whenever Courtney watched her depressing documentary films.
He also liked smashing lady bugs and then laughing maniacally.
Yes, at times, Duncan could seem rather heartless.
But Courtney knew this could never be true.
Duncan was always looking out for her and had a soft spot for his mother. He had never missed one of their anniversaries for anything and was the biggest love muffin on Valentine's day. He enjoyed making peek-a-boo faces to Geoff and Bridgette's baby girl, and he loved cats. Yes, Duncan had a heart.
But dammit, if tonight wasn't one of those nights when Courtney was finding it harder and harder to believe, she wasn't sure what was.
The pregnancy test had been sitting inside her top dresser drawer for years and only when she had forgotten to take her pill two weeks ago did she finally move it from the original spot.
She had checked the back of the box six times to check if maybe, just possibly, the plus sign could mean 'yippee, you aren't preggers'.
No such luck.
She didn't really want a kid either, but Duncan, oh dear lord, Duncan; Duncan had just pissed her off to the moon out there. He had straight up said that he didn't want a kid now. And well, it wasn't her choice in the matter, she wasn't going through with abortion or adoption, the baby was a-coming but Duncan… Duncan could leave.
And that really, really hurt to think about.
Duncan had never threatened to leave but he had never confirmed that his presence was a definite. Of course, they were married but that didn't mean that Duncan couldn't just go out and cheat on her! Duncan was a catch, she saw the way girls looked at him when they went out, hell, the way guys looked at him was a bit creepy sometimes. What if Bridgette- or Geoff, that was an option too- decided Duncan was looking rather good one night and ravished him and what if Duncan liked it and forgot about Courtney? She started pulling her hair when the thought of Duncan with anyone, another woman or man, who wasn't her ate at her heart like misery inducing termites.
Her paranoid self wasn't allowed to continue when Duncan slammed their bedroom door open, a large scowl gracing his face.
"Dammit, get out here so we can go some diapers for my fucking kid. And you can plan the baby shower, you got that? I'll change that little idiot, but only because it's ours, and don't expect me to tolerate your mood swings because they are already fucked up as it is, and-"
She fell into his chest, crying tears of joy when Duncan rubbed his hand through her hair and whispered sweet nothings of how it would be alright. It was times like these when Courtney checked. She heard the most wonderful noise- Duncan's heartbeat, fast, fluttery, there. Alive. With her.
Duncan had a heart. She was sure of it.
Of course, now they would have to move. If anything, this was what Duncan really didn't feel like dealing with.
He had lived in the same place for- quote him- five years, his first place he had ever owned by himself and at this tender age of twenty five he really, really didn't feel like investing in an actual house. His apartment was a one bedroom, one bathroom, one small kitchen and dining room with a nice sized living room type of place. Basically, perfect for him, and Courtney had never complained about the size as well. They had one couch for them both to sit on, a tall table with bar type chairs that didn't let her feet touch the floor, and they had enough food in their fridge for two people.
So now everything had to be bigger.
Courtney had made a list of things for Duncan to look for. While she was busy telling everyone about the baby, calling people about the baby, hell, he wouldn't be surprised if she was making advertisements on television and billboards about this god damned thing, she had made Duncan a list of things to look for in their new house.
A list that ran on into different thoughts, the way Courtney tended to do if you gave her a piece a paper and allowed her to rant. A list that wasn't even a list, it was long enough to be the fucking constitution and dictionary all rolled up into one.
Because a bigger dining room ran into a longer but smaller table which lead to highchairs which led to baby food which led to the option of either breast feeding or formula which led to going to the doctor to ask questions which led to paying for the bill which led to Duncan having to work extra hours while he was also contemplating this thing Courtney dared to call a list.
He rubbed a palm across his face as he approached the seventeenth house he had observed today. He had not been having good luck with this whole 'house touring' thing. Every single time he called Courtney about one, something would come up that wouldn't meet her standards.
The first house had apparently used to be a grave site. ("I am not having our baby turn into a demon or something or other! I am not horror movie material like you.")
The fifth one was the old home of some serial killer who had used to work at Chuck-E-Cheese. ("Duncan, what part of that sentence can you even find remotely funny? Stop laughing, jerk!")
The eight was actually pretty nice looking, but the house had three floors. ("The higher we go, the risk of suicidal thoughts increase! When there is somewhere to jump, our kid might just say, 'Why not?'")
The twelfth? Oh, dear, don't even get Duncan started on that one. ("A slanted driveway? A SLANTED DRIVEWAY? You're trying to kill me, aren't you? You know I HATE hills, Duncan, why the hell should I have to deal with one every time I come home?")
Let's not even mention the one before this one. ("Fuck that! Duncan. Duncan, no, listen to me, Duncan, Duncan! No. Garage. No garage! That's so wrong. It just… Dear lord, NO. I refuse. No. Don't you dare even walk in that house. No, Duncan, I won't! You understand my car is precious, right? What if it storms? Snows? A sandstorm? Huh? Yes, I know we live in Canada. So? There could still be sandstorms, Duncan! If something happens to my car, I'm going to kill you, which will leave the baby fatherless which will result in counseling and therefore an extreme doubt which will always cloud their thoughts which leads to an unsuccessful life and no following in their gracious mother's footsteps. That is the reason why we must have a fucking garage. No, Duncan, I'm not crazy.")
So, finally, at this seventeenth house, the realtor smiled at him, told him the same thing he had at the sixteen other houses ("Trust me, this one is perfect,") and opened the door to the foyer.
And Duncan didn't even call Courtney. It was fucking perfect. The realtor grinned at Duncan's reaction. "So we can start discussing the paper work?"
Duncan's face turned into the biggest shit eating grin ever. Take that, demon baby.
When Courtney first told Bridgette and Gwen about her baby, they could only suspect it was some type of sick joke.
Duncan had ten brothers, three of them younger who, no matter how much he tried to deny it, he loved and cared for. He had changed a diaper before, dealt with babysitting his siblings before, and his mother ran a daycare. He had been around children his entire life.
Courtney had not.
She was an only child and had never had much of a soft spot for anybody except Duncan, if you could call that a soft spot. She wasn't exactly loving, or nurturing, and she liked to pretend that she didn't care most of the time. Plus, Courtney had never even held a baby in her arms before.
In her twenty three years of living, she had never cradled one in her arms before. And now she had one coming.
It had to be a joke.
To think of Courtney with a baby was like thinking of Satan coming down the chimney acting like Santa Claus. It was just fucked up. Courtney was always able to take care of herself, she was independent and knew how to live to the fullest.
So there was no way she could learn to love something so dependent, so needy, and so freaking unlike her.
But they both couldn't deny that they had to have faith. They hadn't seen Courtney this excited since…
"Wow, guys! A lime green colored one-sy! They'll match their daddy… Aww, I bet Duncan was a cute baby. I hope the baby has his eyes. But they should have freckles too. And soft skin and wispy hair… it's gonna be perfect."
…Well, ever.
Geoff looked to Duncan like he had just said the whole world was ending. "A baby."
"Yup." Duncan leaned back on his couch and toed the power button to the X-box 360, loading Call of Duty: World at War and pressing the middle button on the controller to start it up. Geoff waiting for him to clarify but it was a waste. Duncan was too busy throwing a grenade at some animated Korean dude.
"So… you're cool with it?"
"…Yeah. It's my kid. Of course I'm cool."
"…Are you?"
Geoff had always been Duncan's best friend since the beginning. They'd known each other since they were in diapers and even if Geoff was kind of retarded sometimes, that didn't change the fact that he was Duncan's best buddy ever. He'd been his partner on every science project, his roommate during his short time in college as well as his best man during one of the most memorable days of his life.
Geoff had always been Duncan's go to guy.
But the kid was going to change that, wasn't it? Duncan would be too busy teaching his son how to play baseball to talk to Geoff. He'd be Duncan 'number one guy' in his life now.
"Hell yeah, bruh! This is awesome." Duncan smiled.
Geoff held in his pout and put on a grin instead.
Duncan chewed his lip, biting hard enough that the inside of his cheek was bleeding. It was an odd habit he had taken up at a young age and that he had yet to grow out of. He did it whenever he was thinking, like, deeply thinking.
Whenever Courtney saw him doing that, it tended to scare the shit out of her. Nothing good ever came from the words 'deep thinking' and 'Duncan' in the same sentence.
He had been sitting at the kitchen table with that dazed, out of this world look on his face, one cheek placed firmly upon two knuckles in order to push the inside skin near his teeth so he could chew in contemplation.
The only question was over what, exactly.
She sat the food down on the table with a loud bang from the plate, startlingly Duncan and making him curse. "What the hell?"
"What are you thinking about?" Courtney said, taking a seat beside him and shoving a bite of food in with haste. Though she hadn't gotten a baby bump yet this early in to the pregnancy (it has only been three weeks), she could feel something in there, and dammit, if that something wasn't hungry as a mother fucker at all times.
Duncan picked up his fork and took a bite as well, regretting the action instantly. "What is this?"
"You're avoiding the question." She spoke softly, but it was obvious that she was getting annoyed.
"Is that… is that cheese? In sweet potatoes? With pineapple? Okay, we seriously need to talk about the menu-"
"Duncan, god dammit, what were you thinking about?" She yelled, making him swallow the disgusting meal in surprise, his eyes wide. She sighed, running a hand over her face. "Just talk to me, okay? You're making me worried."
His looked softened and he managed a nervous smile. "Just realized that we forgot to our parents about little Princess Junior."
It was Courtney's turn to gain the wide, scared eyes. "Oh, shit."
"Oh shit is right, darling," he frowned, looking down at his plate again. "How about keeping your weird ass cravings to yourself?"
He couldn't say that the sweet potato to the head was unexpected, more like anticipated.
Author stuff:
Yay, new story. Most likely will be 3-4 chapters long. Yes, and if you got pissy due to the long song lyrics at the top, keep it to yourself. I like songs. Sheesh.
Also, huge big mondo thank you to TrueJackVP408, official beta of this story. Boo to the yah, baby.
By the way, did I ever tell any of you guys how much I love ya?
Because guys, your reviews are getting so sweet they make me cry. Like for real, tears running like a waterfall and me fanning myself with a hand and everything. Making me all non-Cereal like. I'm supposed to be cool! Not a cry baby. But I don't mind. I really love them, I read each one and I'm gonna try to start responding more often.
Ok so thanks duckies. You make life worth living :J
Love, Cereal


text:
Mozilla is reporting that there have been nearly 2300 bugs fixed for Firefox 2.0 so far in addition to the memory leaks they have fixed. They also mentioned that the release of Firefox 2 is coming up quickly so they will not be accepting any new bugs unless they block any of these features from working properly:
- Regression/Bug in a planned 1.8.1 feature
- Regression from 1.8
- Security Issue
- TopCrash
- Memory leaks or other major performance issues
- One of the following scheduled and understood issues:
- Visual Refresh
- Pref Panel
- Spell Check
- Tab Overflow
We have now seen most of the new features that Firefox 2.0 will have with the release of Beta 1 last week. We can, however, expect to see the Visual Refresh and the new Preferences Panel in the release of Beta 2.

subset: commoncrawl


text:
A great vacation doesn't have to cost a fortune. In fact, you don't have to spend over $500 on these cruises, which will take you to the Caribbean, Mediterranean, and lots of dreamy places in between. Bonus: some are on new ships! Here, five cruise deals under $500 to... Read More
Even though flying is the main mode of transportation for many travelers, the U.S. still holds onto the romanticism and sense of adventure that is often associated with rail travel. Several historic railroad services still operate daily trains that connect North America — some even enticing passengers with unique vacation packages.... Read More
The Klondike Gold Rush of 1898 may have taken place more than a century ago, but history buffs can still relive it in Alaska and Canada's Yukon Territory. There, sights, museums, and tours like John Hall's Alaska Klondike Gold Rush Tour and those by Klondike Tours allow you to get into the Gold Rush spirit... Read More
No offense to the chocolate lovers in Hershey, Pennsylvania, but Québec might really be the sweetest place on Earth. The Canadian province produces about 75 percent of the world's maple syrup and maintains an emergency reserve (for surprise pancake surpluses?) of about 46 million pounds. The value of the ooey-gooey... Read More
Niagara County, which straddles the U.S. and Canada, is best known for one of the world's most famous and most recognizable natural wonders. But while Niagara Falls has delighted visitors for decades — earning it the title of "honeymoon capital of the world" — there's plenty to see beyond the falls... Read More
At the heart of it, "Star Trek" shares a lot with the traveler's ethos: excitement over new adventures, a respect for diversity and culture, and an enthusiasm for all that reminds us of our humanity. For a Trekkie, the special exhibits and experiences that are currently on offer in celebration... Read More
Sitting on the edge of the St. Lawrence River, Québec City exudes a certain vibe or, maybe more aptly, a certain joie de vivre. The provincial capital of Québec, Canada is a thoroughly modern city, but it also has the beautifully preserved romance of a centuries-old European town. From... Read More
Canada is having a moment. Progressive Prime Minister Justin Trudeau is garnering international attention with his unabashed support of LGBT and women's rights and his welcoming stance on immigration. And the country's abundant natural parks, rich flavors, and cosmopolitan cities drew a record number of tourists last year: 14.03 million overnight visitors and 26 million on day trips... Read More
Prince Edward Island is the crown jewel of Canada's Maritime Provinces, thanks to pristine beaches, fresh local seafood, and charming 19th century architecture. Only slightly larger than the state of Delaware, the island is easy to navigate in a short period of time, which is good because there's a lot to see.... Read More
Montréal is a must-visit — even if you only have a few hours to spare. With a history that dates back to 1642, Canada's second largest city is vibrant and diverse; it's filled with great food and proud locals willing to help you find your way around. From the best place to try its... Read More
Whether you're traveling for business or pleasure, it's rare and exciting when a hotel offers breakfast that goes beyond wet scrambled eggs and mini pastries. These 10 hotel breakfasts will inspire you to get down to the dining room early or to splurge on room service. Archer Hotel, Austin, TX When the Archer Austin hotel opens in September, it will... Read More
With a travel warning and heightened terror alerts throughout Europe, some people find themselves concerned about jetting off to Paris or Berlin. Though opinions on the safety levels of these cities are hotly debated and constantly changing, if you are looking for alternatives to a European vacation — whether due to... Read More
With its cobblestone streets and Old World charm, Québec City can be a budget-friendly alternative to a European vacation, as long as you know what's worth the splurge (and what's not). If you don't, though, the expenses (minus airfare) can rival their overseas counterparts. Keep your budget in check on your next... Read More
Nearly 30 years ago, English actor Peter Ustinov described Toronto as, "New York operated by the Swiss." The idea that Toronto offers the cultural attractions of the Big Apple without the chaos — and the cost — is truer than ever. Due to decreasing oil prices, the Canadian dollar is now valued at... Read More
Set on picturesque Lake Ontario, Centre Island is a popular getaway from downtown Toronto. Though it's just one of the many Toronto Islands, Centre Island stands out for its wide range of attractions, enjoyed by locals and tourists alike. Just 15 minutes by ferry from Queens Quay, the island is easy to reach; and... Read More


text:
Subscribe on iTunes or Stitcher.
Spencer is an American family physician who specializes in helping people with obesity. He helps his patients with lifestyle interventions first, via diet and exercise, before using to his prescription pad wherever possible.
We talk about many topics: why obesity has been recently classified as a disease, why calories in vs calories out is what determines weight loss, but telling someone to eat less and move more doesn't generally work, how Spencer gets buy-in from his patients, how certain medicines can cause side effects that hamper weight loss, how to look at and interpret your cholesterol numbers, and the potential dangers of bulletproof coffee.
Listen or download this episode on Soundcloud. (Direct RSS feed URL for other players.)
Show notes
- Why Spencer puts diet and exercise first. [0'30]
- The reasons why doctors don't generally put diet and exercise as medicine first. [3'00]
- How Spencer gets 'buy in' from patients. [6'30]
- Why obesity has been classified as a disease [10'30]
- "Is it not just about calories in, calories out?" – "Yes but not entirely." [13'30]
- The importance of controlling your food environment. [19'00]
- "I don't feel that fixing one habit at a time is the best way for people." [22'00]
- "The data shows that people who lose weight rapidly in the beginning tend to do the best." [23'30]
- Is a donut less delicious to some people? [26'00]
- Why Spencer wrote The Fat Loss Prescription [29'00]
- There was no book out there that I could give to my patients.
- Spencer talks about how medicines can cause side effects that hamper weight loss. [34'00]
- In the current system I can't do what I want to do for my patients. [39'00]
- Cholesterol talk. How to look at and interpret your cholesterol numbers. [41'00]
- Bulletproof coffee and the damage it can cause. [47'00]
Selected links
- DrSpencer.com
- Docswholift.com
- Twitter – Facebook – Instagram
- Spencer's book, The Fat Loss Prescription on Amazon
- The Fitness Summit in Kansas City
Thank you for listening! – Andy and Spencer
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text:
10 Best Art Galleries in Metro Phoenix
Roosevelt Row is home to some of the best galleries in Phoenix.
Lynn Trimble
Metro Phoenix is home to an assortment of art galleries exhibiting works by local, national, and international artists. Most show works in a wide variety of media, and many show works by both emerging and established artists. They've all got a different feel, so whatever your interests and tastes, you'll find something that catches your fancy.
But 10 metro Phoenix galleries stand above the rest. One is a converted shipping container, and two are located in former warehouses. Another is subterranean, and one sits on the second story of a quaint retail complex. One is owned by a city, and a couple are owned by community activists. Here are our favorites.
Modified Arts
Located in the Roosevelt Row arts district, Modified Arts was established by Kimber Lanning in 1999 as a visual and performance art space. Today, it's both an art gallery and office space for the nonprofit Local First Arizona, which Lanning founded. The gallery presents mostly local artists, but also national and international artists making contemporary art in a variety of media. Local First Arizona staff open the space Monday through Friday 9 a.m. to 5 p.m. Gallery staff are onsite for First Friday from 6 to 10 p.m., for Third Friday from 6 to 9 p.m., and Saturday from noon to 4 p.m. Find more information on the Modified Arts website.
Bentley Gallery at Bentley Projects exhibits works by local to international artists.
Lynn Trimble
Bentley Gallery at Bentley Projects
Bentley Calverley founded Bentley Gallery in Scottsdale in 1984. In 2004, she went on to open a second art space in a warehouse that she dubbed Bentley Projects. In November of 2012, the Scottsdale gallery moved to Bentley Projects, where it's since been renovated. Bentley Gallery specializes in contemporary art, Asian antiquities, and works from the Modern era. Previous exhibitions have featured works by renowned artists Keith Haring, Chuck Close, Devorah Sperber, and Dale Chihuly — in addition to works by such local artists as Colin Chillag, Joe Willie Smith, and Denise Yaghmourian. Bentley Gallery is open Tuesday through Saturday, 9:30 a.m. to 5:30 p.m. Find more information on the Bentley Gallery website.
Art Intersection in Gilbert specializes in the intersection of photographic arts with other media.
Lynn Trimble
Art Intersection
Art Intersection, founded by Alan Fitzgerald in January 2011 inside a former dance studio, specializes in the intersection of photography with other forms of artistic expression. It exhibits works by established and emerging artists, including students, in two conjoined galleries with a total of 1,670 square feet on the second floor of the Heritage Court Building in downtown Gilbert. Notable artists who've shown works at Art Intersection include David Emitt Adams, Claire A. Warden, and Lisa Robinson.
Often, you'll find additional works exhibited in its Ryan Gallery, which doubles as a conference room. Art Intersection has an additional "art for advocacy" space called Gallery 4 on the building's first floor, where it exhibits works designed to foster reflection, conversation, and community engagement with social, environmental, and cultural issues such as civil rights and homelessness. They also have a photographic lab, and offer a wide variety of classes for photographers with varying levels of experience. Art Intersection is open Tuesday through Saturday 10 a.m. to 6 p.m. Find more information on the Art Intersection website.
Chartreuse is located in the Grand Avenue arts district.
Lynn Trimble
Chartreuse is located in the historic Bragg's Pie Factory building, which the Bragg family had built in 1947. Nancy Hill, whose Hazel & Violet letterpress business is also located in this building, opened Chartreuse in September 2015. Previously, the space was home to Beatrice Moore's Frontal Lobe Community Space and Gallery. Chartreuse is a cool place to see art while enjoying a bit of Phoenix history in what's now dubbed the Grand Avenue arts district. Check out the green bike lanes, street names painted at intersections, and planters decorated by artists while you're there. Chartreuse participates in First and Third Friday events in Phoenix. The venue presents solo and group exhibitions featuring works by artists in and beyond Arizona, which typically rotate every month. The gallery is open First and Third Fridays 6 to 10 p.m. Find more information on the Chartreuse website.
Hot Box Gallery is located in a shipping container on Roosevelt Row.
Lynn Trimble
Hot Box Gallery
The Hot Box Gallery, established in January of 2014 with funding from an ArtPlace grant, was the first of three shipping container galleries to open in Roosevelt Row. Phoenix Institute of Contemporary Art programs all three galleries with solo and group exhibitions, which typically open on Third Fridays, and feature local or international artists. These galleries are slated to become part of an artist live/work space during 2016, which will include exhibition space. The galleries are open First and Third Fridays 6 to 10 p.m. Find more information on the Roosevelt Row Community Development Corporation website.
Lisa Sette Gallery
After decades in the downtown Scottsdale arts district, Lisa Sette Gallery moved in June 2014 to a semi-subterranean Al Beadle building in midtown Phoenix. Sette seeks out diverse artists "working on the leading edge of aesthetic, social, and conceptual investigation." She currently represents 35 established and emerging artists working in a wide variety of media, and presents several exhibitions featuring their works each season. The roster includes famed light artist James Turrell and William Wegman, best known to many for photographing his own Weimaraner dogs in various costumes and poses. Sette also represents several metro Phoenix favorites, including Rachel Bess, Angela Ellsworth, and Carrie Marill. The gallery is open Tuesday through Friday from 10 a.m. to 5 p.m. and Saturday from noon to 5 p.m. Find more information on the Lisa Sette Gallery website.
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Flader - details and analysis
The word Flader has a web popularity of 932000 pages.
What means Flader?
The meaning of Flader is unknown.
What is the origin of name Flader? Probably Italy or Denmark.Flader spelled backwards is Redalf
This name has 6 letters: 2 vowels (33.33%) and 4 consonants (66.67%).
Anagrams: Ladfer Rfaeld Rfeald Lrafed Radefl Dfarle Rdafle Ldarfe
Misspells: Flsder Fladet Fllader Fladel Flade Fladera Falder Fladre Flaedr
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|Jody Flader
|Andrea Flader


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Memes related to Fardeen Khan's weight gain may have gone viral, but the actor remains unfazed.
Also read: Fardeen Khan responds to body shamers: It proves that they are nothing more than a bunch of cowards
Fardeen Khan
He tweeted: "Not ashamed, not shamed, not offended, not depressed, not blind either. Happy! Living the happiest chapter thus far with LBS to show for it!"
Also read: Twitter goes into overdrive 'body-shaming' Fardeen Khan


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North Parkes Mines getting in the swing of things at the festival!
A small central west town Parkes holds an annual Elvis Festival each year on or around the kings birthday. This year would have been his 70th. The Parkes population swells from 10,000 to this year 25,500! This is the largest Elvis gathering in the Southern hemisphere. A superb weeks entertainment for all the family.
I was fortunate to be media accredited for the Country Link Calendar & enjoyed taking many images, some of which I'll share here.
Canon EOS 5D mark ll
Canon 28-135mm lens
Thank you for looking :)


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In conjunction with Glen Klecker, Kizer has produced this hefty folder with excellent detail. The clip point blade is made of S35VN steel and has a stonewash finish and the Kizer logo embossed near the spine. The right hand thumb stud opens the blade and the liner lock holds it in place. The textured, tan G-10 scales add security to the grip. The handle material is 6AL4V Titanium as is the tip-up, right hand pocket clip. There is also a lanyard hole for alternate carry methods. A solid knife with a good feel in the hand.
Overall Length: 9.25"
Blade Length: 3.75"
Steel: CPM-S35VN
Handle: G-10
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Targa Resources PartnersDividend Yield: 5.80% Targa Resources Partners (NYSE: NGLS) shares currently have a dividend yield of 5.80%. Targa Resources Partners LP provides midstream natural gas, natural gas liquid (NGL), terminaling, and crude oil gathering services in the United States. The company operates in two divisions, Gathering and Processing, and Logistics and Marketing. The company has a P/E ratio of 40.33. The average volume for Targa Resources Partners has been 441,400 shares per day over the past 30 days. Targa Resources Partners has a market cap of $4.9 billion and is part of the energy industry. Shares are up 24.9% year to date as of the close of trading on Thursday. TheStreet Ratings rates Targa Resources Partners as a buy. The company's strongest point has been its expanding profit margins. We feel these strengths outweigh the fact that the company has had sub par growth in net income. Highlights from the ratings report include:
- TARGA RESOURCES PARTNERS LP has exprienced a steep decline in earnings per share in the most recent quarter in comparison to its performance from the same quarter a year ago. The company has suffered a declining pattern of earnings per share over the past year. However, we anticipate this trend reversing over the coming year. During the past fiscal year, TARGA RESOURCES PARTNERS LP reported lower earnings of $1.20 versus $1.98 in the prior year. This year, the market expects an improvement in earnings ($1.21 versus $1.20).
- NGLS, with its decline in revenue, underperformed when compared the industry average of 1.3%. Since the same quarter one year prior, revenues fell by 21.0%. Weakness in the company's revenue seems to have hurt the bottom line, decreasing earnings per share.
- Compared to where it was a year ago today, the stock is now trading at a higher level, regardless of the company's weak earnings results. The stock's price rise over the last year has driven it to a level which is somewhat expensive compared to the rest of its industry. We feel, however, that other strengths this company displays justify these higher price levels.
- The gross profit margin for TARGA RESOURCES PARTNERS LP is currently extremely low, coming in at 11.40%. Regardless of NGLS's low profit margin, it has managed to increase from the same period last year. Despite the mixed results of the gross profit margin, the net profit margin of 2.18% trails the industry average.
- Net operating cash flow has decreased to $149.90 million or 28.48% when compared to the same quarter last year. In addition, when comparing to the industry average, the firm's growth rate is much lower.
- You can view the full Targa Resources Partners Ratings Report.


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It has been suggested that changes in adiponectin levels may contribute to improved insulin sensitivity in insulin-resistant individuals both after weight loss and after treatment with thiazolidinedione compounds. If this is correct, then changes in total circulating adiponectin and/or distribution of its multimeric complexes should coincide with improvements in insulin sensitivity after both interventions. To address this issue, fasting adiponectin concentrations and distribution of adiponectin complexes were measured in plasma samples in 24 insulin-resistant, nondiabetic subjects before and after 3–4 mo of treatment with either rosiglitazone or caloric restriction. The degree of insulin resistance in each group of 12 subjects was equal at baseline and improved to a similar extent (∼30%) after each therapy. Whereas total adiponectin levels increased by nearly threefold and the relative amount of several higher molecular weight adiponectin complexes increased significantly in the rosiglitazone treatment group, there were no discernible changes in adiponectin levels or in the distribution between high or low molecular weight complexes in the weight loss group. These data indicate that, although changes in total adiponectin and several specific adiponectin complexes paralleled improvements in insulin resistance in thiazolidinedione-treated subjects, neither circulating adiponectin concentrations nor multimeric complexes changed in association with enhanced insulin sensitivity after moderate weight loss in 12 insulin-resistant, obese individuals.
- thiazolidinedione
- adiponectin multimers
- high molecular weight complexes
adiponectin is a ∼30-kDa protein produced by adipocytes, which circulates in plasma in multimeric aggregates of different sizes and has been closely associated with insulin action (7, 25). Total circulating adiponectin levels have been shown to be lower in insulin-resistant individuals (1, 27), and both over- and underexpression of adiponectin alters insulin sensitivity in animal models of insulin resistance (4, 29). Furthermore, in vitro and in vivo studies have demonstrated several possible mechanisms for the beneficial actions of adiponectin, including enhanced hepatic insulin sensitivity (4), an increase in fatty acid oxidation (9), and decreased inflammatory activity (20). In light of these observations, it has been suggested that interventions that improve insulin sensitivity may accomplish this through modulation of adiponectin levels, and this notion is consistent with evidence that plasma adiponectin concentrations increase when insulin-resistant individuals, either nondiabetic or with Type 2 diabetes, are treated with thiazolidinedione (TZD) compounds (13, 17, 33).
On the other hand, not all interventions that enhance insulin sensitivity are associated with significant changes in plasma adiponectin concentrations. For example, plasma adiponectin levels do not significantly increase in response to two therapeutic modalities that clearly improve insulin action, namely, moderate weight loss (∼8.0 kg) (2, 28) and increases in physical activity (14, 18, 31). There are several possible explanations for these discrepant results. First, a functional peroxisome proliferator-activated receptor-responsive element in the adiponectin promoter has recently been identified that is thought to play a significant role in the transcriptional activation of adiponectin gene in adipocytes (15). Thus it could be argued that the increase in adiponectin concentrations in TZD-treated insulin-resistant individuals was a direct effect of the drug itself, and changes in adiponectin are not responsible for improved insulin resistance resulting from all treatment modalities. Second, the apparent divergent changes in plasma adiponectin concentrations following moderate weight loss and increased physical activity vs. TZD treatment could also be explained by differences in either the baseline degree of insulin resistance and/or the improvement in insulin resistance after each of the interventions. Third, although adiponectin is synthesized as a ∼30-kDa monomer, it circulates as a variety of multimeric forms, including homotrimers (70–90 kDa) and larger oligomers, and a high molecular weight (HMW) form consisting of six trimers (21). Evidence indicates that these multimers vary in their biologic activities, and it has been suggested that the proportion of adiponectin in the HMW form is a more accurate indicator of insulin sensitivity than total adiponectin levels (21, 22). Therefore, there may be changes in the absolute or relative levels of various adiponectin multimers that explain the improvement in insulin resistance accompanying weight loss. Finally, because moderate weight loss (unlike TZD treatment) is not associated with changes in circulating levels of adiponectin (2, 28), other factors may contribute to improvements in insulin sensitivity in this setting. The present study was initiated to evaluate these various possibilities and involved directly comparing the changes in total plasma adiponectin concentrations and the distribution of adiponectin multimers that were seen in response to TZD treatment with those before and after weight loss in insulin-resistant subjects that were matched for both baseline insulin resistance and the degree to which the defect in insulin action improved with each therapeutic intervention. If variations in adiponectin are largely responsible for improvements in glucose metabolism following most typical therapeutic interventions, then changes in plasma adiponectin and/or distribution of its complexes should reflect improvements in insulin sensitivity after both moderate weight loss and TZD treatment.
The study included 24 subjects selected from a larger group of volunteers who had participated in studies at Stanford University's General Clinical Research Center examining the effect of weight loss (19) and treatment with rosiglitazone (5) on insulin resistance and cardiovascular disease risk factors. Participants for these studies were recruited from the San Francisco Bay area through advertisements in local newspapers. Each volunteer signed a written informed consent before admission to the General Clinical Research Center. All study participants were determined to be nondiabetic according to the criteria of the American Diabetes Association (5a) and were required to have normal findings on history, physical examination, and routine chemical screening battery, including hematocrit, creatinine, and alanine transaminase levels. Degree of adiposity was assessed by body mass index (BMI), and all subjects with BMI ≥35.0 kg/m2 were excluded from the studies. Volunteers selected for the weight loss study were required to have a BMI of 30.0–34.9 kg/m2. There were no specific BMI inclusion values for the rosiglitazone-treated group, and BMI ranged from 21.9 to 34.8 kg/m2. The study protocol was reviewed and approved by the Institutional Review Board at Stanford University.
Study subjects underwent an insulin suppression test to quantify insulin-mediated glucose disposal as originally described (10) and validated by our research group. Briefly, after a 12-h overnight fast, subjects were infused for 180 min with octreotide acetate (0.27 μg·m−2·min−1), insulin (32 mIU·m−2·min−1), and glucose (267 mg·m−2·min−1). Blood was drawn at 10-min intervals from 150 to 180 min of the infusion to measure plasma glucose and insulin concentrations, and the means of these four values were used as the steady-state plasma insulin and glucose (SSPG) concentrations for each individual. Because steady-state plasma insulin concentrations were similar in all subjects during these tests, the SSPG concentration provided a direct measure of the ability of insulin to mediate disposal of an infused glucose load; the higher the SSPG concentration, the more insulin resistant the individual. On the basis of the results of the insulin suppression test, participants with SSPG concentrations >180 mg/dl were defined as being insulin resistant and were eligible for this study. This cutoff point was chosen based on the results of a previously reported distribution of SSPG concentrations (32) where approximately one-third of the 490 nondiabetic subjects had SSPG concentration values above 180 mg/dl.
To accomplish the goals of our study, we selected 24 nondiabetic insulin-resistant subjects, matched for age and gender distribution, who had similar SSPG concentrations before and after administration of rosiglitazone (n = 12) or weight loss (n = 12). Rosiglitazone-treated subjects received 4 mg/day for 4 wk, followed by 8 mg/day for 8 wk, while maintaining their usual diet. All baseline measurements were repeated at the end of 12 wk of treatment. The weight loss group included volunteers with a BMI between 30.0 and 34.9 kg/m2. All subjects were instructed by a certified dietitian on calorie-restricted diets calculated to lead to a weight loss of 0.5 kg/wk. The period of weight loss was 4 mo in duration, during which time subjects were seen bimonthly to be weighed and receive dietary advice. At the completion of the weight loss phase, subjects were instructed on a weight-maintenance diet. After 2 wk of stable weight, all measurements performed at baseline were repeated.
Plasma glucose and insulin levels were measured as described previously (32). Plasma adiponectin levels were measured on blood samples drawn before the initiation of the insulin suppression test with a radioimmunoassay established by Linco Research (St. Charles, MO). This assay has a sensitivity of 1 ng/ml, a range of 500 ng/ml to 100 μg/ml, when samples are diluted 1/500 as per manufacturer's instructions, and intra- and interassay coefficient of variation of <8%.
Analysis of the multimerization status of circulating adiponectin was performed by size fractionation of plasma samples using SDS-PAGE under nonreducing, nondenaturing conditions, as described (with minor modifications) by Waki et al. (26). Plasma was combined with a 4× Laemmli sample buffer, prepared without β-mercaptoethanol. Sample preparation was performed at room temperature. Samples, equivalent to 2 μl of plasma, were size fractionated on 3–8% polyacrylamide gradient gels in a Tris-acetate system. Proteins were transferred to nitrocellulose membranes and blocked for 3 h at room temperature with 5% milk in Tris-buffered saline, pH 7.5. Membranes were incubated with a monoclonal antibody against human adiponectin (BD Biosciences, Palo Alto, CA), at a 1:500 dilution for 1 h at room temperature. The secondary antibody was anti-mouse IgG conjugated with horseradish peroxidase (Amersham Biosciences, Buckinghamshire, UK). Bands were detected using SuperSignal West Pico chemiluminescent substrate (Pierce, Rockford, IL) and captured on Hyperfilm ECL film (Amersham Biosciences). Quantitative densitometry was performed using ChemiImager software (Alpha Innotech, San Leandro, CA), and, after subtracting the background density, data were presented as average density per band. Each subject sample was run at least two or three separate times and yielded consistent results. Bands were compared with HiMark Unstained HMW protein standards from Invitrogen (cat. no. LC5688). Manufacturer's instructions were followed to visualize the bands using Coomassie blue. A single lot of standards was used for all the gels. One limitation to the SDS-PAGE is the semiquantitive nature of the results. However, the ability to assess multiple pre- and posttherapy samples on the same gels makes this approach an excellent method to directly compare the effects of different interventions.
Summary statistics are described as means ± SD. The two study groups were compared using Student's unpaired t-test and χ-square test. Within each study group, changes in clinical and metabolic variables were compared using Student's paired t-test. Finally, Pearson's correlation coefficients were calculated between the changes in SSPG and adiponectin concentrations in response to the interventions.
Baseline characteristics of the study population are given in Table 1. The groups were similar in terms of age, gender distribution, SSPG, and fasting plasma glucose and insulin concentrations. However, based on the inclusion criteria for the two different intervention arms, BMI was greater in those who participated in the weight loss program.
Table 2 compares the effects of the two experimental interventions on body weight, BMI, SSPG concentrations, and fasting plasma glucose and insulin concentrations. Participants in the weight loss group lost an average of 7.4 kg (8% of initial weight, P < 0.001), whereas rosiglitazone-treated subjects gained 1.3 kg (P = 0.03). As a consequence of these changes in opposite directions, weight at the end of the study was nearly identical in the two groups.
SSPG concentrations were essentially identical in the two groups before weight loss (Table 2), declined significantly and to a comparable degree after each intervention (29% vs. 30%), and were again quite similar at the end of the study. In association with the improvement in insulin sensitivity, fasting plasma glucose and insulin concentrations decreased significantly (P < 0.05) and to a similar extent in both groups.
Figure 1 depicts plasma adiponectin concentrations before and after the two experimental interventions. Mean baseline adiponectin levels were not statistically different (P = 0.30) between the rosiglitazone-treated (10.9 ± 5.0 μg/ml) and weight loss (9.0 ± 3.2 μg/ml) groups. Plasma adiponectin concentration increased in every rosiglitazone-treated subject, with a tendency for the increment to be greatest in individuals with the highest baseline values. The overall increase in adiponectin concentration after rosiglitazone treatment (to 24.8 ± 11.6 μg/ml) was highly statistically significant (P < 0.001), and there was no relationship between the modest change in weight seen in these subjects and the increase in adiponectin after administration of rosiglitazone.
In marked contrast, plasma adiponectin concentrations remained unchanged in association with the enhanced insulin sensitivity following weight loss, with values increasing slightly in five subjects, decreasing slightly in six others, and not changing in one subject. As a consequence, plasma adiponectin concentrations at the end of the study were approximately threefold greater (24.8 ± 11.6 μg/ml, 95% confidence interval of 17.4–32.1, vs. 8.9 ± 3.1 μg/ml, 95% confidence interval of 7.0–10.8; P < 0.001) in rosiglitazone-treated subjects, despite the fact that both the improvement and the final level of insulin sensitivity were similar in the two groups. Furthermore, there was no correlation in the entire group between the improvement in insulin sensitivity and increases in plasma adiponectin concentration in response to the experimental treatments (r = 0.12, P = 0.59).
To assess whether changes in specific adiponectin multimeric complexes, rather than total plasma adiponectin concentration, may have accounted for enhanced insulin sensitivity after either intervention, we compared relative levels of each of the major adiponectin forms present in plasma as determined by density measurement of each band identified on the gradient gels. This analysis revealed seven or eight different bands ranging in size from ∼90 kDa, most probably the trimeric form, to a HMW form, >400 kDa (Fig. 2). If samples were more extensively heated and denatured before addition to gels, the number of bands were typically reduced to the 30- and 90-kDa forms (data not shown), consistent with a reduction in multimerization of adiponectin as previously described (21, 26). The averaged results from analysis of multiple gels are shown in Table 3, and it can be seen that several differences between the two groups were observed. First, the relative amount or distribution of each adiponectin complex, expressed as percentage of total adiponectin for each individual, varied between groups at baseline. The major difference was that the weight loss group had a lower percentage of the HMW complex, whereas percentages of other complexes did not differ between the two groups before the interventions. Second, whereas there were increases in the relative amounts of the HMW adiponectin band and the 200-kDa band in the rosiglitazone group after treatment (Table 3), there was no such shift in the distribution among adiponectin multimers from the plasma of the weight loss group. Representative examples of this are shown in Fig. 2. In support of this overall finding was the observation that the percentage of total adiponectin present in the HMW complex increased after treatment in all 12 of the subjects receiving rosiglitazone (with or without accompanying weight gain), whereas this only occurred in 3 of the 12 subjects in the weight loss group. There was also a significant decrease in the percentage of total adiponectin present in the ∼170-kDa band in the rosiglitazone group. There were no other consistent changes in adiponectin multimer distribution in rosiglitazone subjects, and there were no consistent changes in the relative amounts of any adiponectin multimers in the weight loss group.
A major goal of this study was to clarify the nature of the relationship between plasma adiponectin concentrations and resistance to insulin-mediated glucose disposal. Perhaps the most useful way to view our results from this perspective is to begin by identifying areas of common agreement concerning this issue. In this context, several previous studies have shown that improved insulin sensitivity following TZD treatment is associated with increases in plasma adiponectin concentrations (3, 12, 22, 23, 33). More recently, Pajvani et al. (22) have shown, using velocity sedimentation methodology to identify circulating adiponectin complexes, that the increase in plasma adiponectin following TZD therapy in subjects with Type 2 diabetes or insulin resistance is also associated with greater amounts of larger multimeric forms of adiponectin. Similar to Waki et al. (26), we used a SDS-PAGE method to measure adiponectin complex distribution in plasma, and our results are quite similar to those of Pajvani et al. (22) in that we also observed an increase in the very highest molecular mass band and, to a lesser extent, in a 200-kDa band, whereas they described an increase in adiponectin complexes that appears to include a range of HMW adiponectin complexes (22). The most likely explanation for the relatively minor discrepancies between the results of the two studies is the difference in the methods used to measure adiponectin mulitimers.
Thus there is general agreement that TZD treatment is associated with enhanced insulin sensitivity, higher plasma adiponectin concentrations, and an increase in HMW forms of adiponectin. Although there is accumulating evidence that TZD-associated changes in adiponectin concentration and/or multimer distribution may mediate improved insulin sensitivity, it remains possible that the changes in insulin action and adiponectin concentration and size distribution represent separate and unrelated TZD effects. Consistent with this possibility was our inability to discern a significant relationship following TZD administration between the enhanced insulin sensitivity and the changes in plasma adiponectin concentration. The results of the recent report by Hammarstedt et al. (12) also show that insulin sensitivity improves, associated with increases in plasma adiponectin concentration and a shift to a HMW form, subsequent to pioglitazone administration in insulin-resistant, nondiabetic individuals. However, as was the case with our study, there was no relationship between the enhanced insulin sensitivity and the changes in adiponectin amount or multimer distribution. It is possible that the lack of a relationship between changes in insulin action and adiponectin concentration is due to the relatively few number of patients in both studies and/or the fact that they were all insulin resistant. In any event, there appears to be relative unanimity concerning the fact that administration of TZD compounds to insulin-resistant individuals leads to enhanced insulin sensitivity, increases in total adiponectin concentration, and a shift to HMW forms. What is not so clear is the nature and strength of the relationship between these metabolic changes.
There is less agreement concerning the effect of weight loss on plasma adiponectin concentrations. The results of the present study, as well as previous findings of our research group (2) and those of Xydakis et al. (28), indicate that insulin sensitivity improves after relatively moderate weight loss in the absence of any change in plasma adiponectin concentration. In contrast, evidence has also been published that the improvement in insulin action associated with weight loss is accompanied by higher plasma adiponectin concentrations (6, 11, 30). However, these studies differed from ours in two important ways. First, the magnitude of obesity at baseline in these latter studies was much greater; bariatric surgery was used to induce weight loss, resulting in relatively massive amounts of weight loss, i.e., 23 kg to almost 57 kg (6, 11, 30). This approach is quite different from ours in which moderate calorie restriction was instituted to bring about weight loss of 8–9 kg. Furthermore, we directly measured the improvement in insulin sensitivity after moderate weight loss, whereas surrogate measures, based on changes in plasma insulin concentration, were used to assess insulin action in those studies in which massive weight loss was associated with increases in plasma adiponectin concentration. Although these estimates of insulin action are correlated with specific measures of insulin-meditated glucose disposal, they account for < 40% of the variability from person to person when insulin-mediated glucose disposal is measured directly (32). The limitation of insulin concentrations as indicators of insulin action is accentuated in obese individuals because obesity, per se, results in decreased insulin clearance (8, 16). Thus large amounts of weight loss will result in lower insulin concentrations, in excess of any associated improvement in insulin sensitivity, and their use in this situation cannot provide reliable estimates of insulin action. It is also worth noting that the increment in adiponectin concentration following massive weight loss was substantially less than that described following TZD administration (13, 17, 33). Thus, although changes in plasma adiponectin concentration may vary as a function of the amount of weight lost, insulin sensitivity can improve after moderate weight loss in the absence of any change in plasma adiponectin, and the increase in adiponectin concentration with even massive weight loss is attenuated compared with the changes seen after TZD treatment.
In contrast to previous studies, ours was explicitly designed to elucidate the relationship between adiponectin and treatment-induced changes in insulin sensitivity. Furthermore, ours is the only study that directly compared the effects of rosiglitazone administration vs. those of moderate weight loss on both insulin action and adiponectin concentration and its multimeric complex distribution. Finally, the impact of the two treatments was compared in insulin-resistant, nondiabetic subjects, well matched at baseline for age, gender, and degree of insulin resistance. The similarity of the two groups before treatment permits us to more confidently compare the impact of the two interventions on the relationship between treatment-induced changes in insulin action and plasma adiponectin concentrations. The results presented clearly demonstrate that the relationship between these variables varied dramatically as a function of the intervention. Despite essentially identical improvement in insulin sensitivity, the changes in plasma adiponectin concentrations were quite disparate. Whereas increases in total adiponectin and several higher molecular weight complexes paralleled improvements in insulin resistance in TZD-treated subjects, we report the novel finding that no changes in adiponectin concentrations or molecular weight complexes were observed when insulin sensitivity improved to a similar degree after weight loss. As indicated above, exercise-mediated improvements in insulin sensitivity also appear independent of changes in total adiponectin levels (14, 18, 31). Thus it is possible to dissociate improvements in insulin sensitivity from increases in adiponectin concentration, supporting the notion that changes in adiponectin may not be instrumental in improving insulin resistance in all therapeutic settings. As a corollary, it appears that other factors (e.g., other adipokines or cytokines produced in adipose tissue or elsewhere) may play a role in the improvement in insulin-mediated glucose disposal that occurs when insulin-resistant individuals lose a moderate amount of weight.
This work was, in part, supported by the office of Research and Development, Medical Research Service, Department of Veterans Affairs, and by research grants from the Department of Veterans Affairs, the National Institutes of Health Grants RR-00070 and HL-067690, and the American Diabetes Association (to T. P. Ciaraldi).
The costs of publication of this article were defrayed in part by the payment of page charges. The article must therefore be hereby marked "advertisement" in accordance with 18 U.S.C. Section 1734 solely to indicate this fact.
- Copyright © 2006 the American Physiological Society


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|By Toph's Fanboy
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|Staying in the Bu Shufu Di Difang
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3 (Unexpected Twists)
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She woke up flat on her back early the next morning, while the air was still relatively cool. Pushing Momo from the place on her stomach where he had apparently come to rest the night before after she had fallen asleep, Toph stood up and snapped her body back and forth in an attempt to get a kink out of her back which had developed from her somewhat awkward change of positions the night before. She turned around in order to feel whether anyone else was up behind her. A few of the older Jiandan family members appeared to be just getting up, but Sokka was still in his sleeping bag, sounding as if he would snore his life away without ever getting up. Good, she thought, I have no idea what I would do if he was awake.
Without a word to anyone else, she walked toward the door and moved outside, hoping a breath of fresh air would help her clear her head so she could figure out what to do with what she now looked at as a very odd situation. She sensed Aang was over at the nearby barn, and so she meandered over to him, thinking that talking with her old friend might help her return to the world which made sense to her.
He appeared to hear her arrival when as he Airbended himself upwards to get breakfast for Appa, saying after he had landed on the ground again, with his back still turned, "Mornin', Toph."
"Mornin', Twinkle-Toes." Phew, she thought with relief at the normalness of their greetings. This is more like it.
After he was done feeding his bison, Aang turned around to speak to her directly. Though he seemed about to say something at first, he then paused before he went on in a different tone of voice, "You look different with your bangs out of your eyes, Toph."
Her back stiffening up straighter, she realized suddenly that she was giving him evidence of hers and Sokka's kiss the night before without even trying. CRUD! Feeling incredibly embarrassed, she could hardly resist the urge to slap herself in the forehead to punish herself for failing to do anything about it, but managed to restrain herself by reminding herself that doing so would ultimately prove even more embarrassing. "Does it really matter, Aang?" she nervously asked, trying to make it sound like an rhetorical question, and that she would take it as a personal insult if Aang didn't answer in the negative.
"Not really..." Aang answered slowly, his voice telling her that the way she asked her question had given him more warrant to be suspicious then she had hoped for. She felt rather tense for several minutes until Aang finally spoke up again, his mind (thankfully) seeming to have moved onto a different subject. "We might as well get going now, while Appa's full and happy. Is Sokka up yet?"
"Not yet," she answered. "I'll go back in and wake him up, if you want."
Aang nodded, and she half-ran back inside. The world's gone crazy! Now I'm even feeling uncomfortable around Twinkle-Toes! She thought as she rushed towards the door, going just slowly enough so as to not cause more problems for herself. She was relieved when she was inside and away from his suspicious eyes, which she feared more at the moment than whatever Sokka's reaction was going to be to their joint experience of the night before. She felt Sokka standing up and moving his head around in a circle in an attempt to remove the sleepiness from his mind, and met him half-way as he walked over to her.
She put her arm behind her head and rubbed her neck as she tried to ask him about the previous night, "So...?"
"Wha...?" He said, clearly not understanding her unstated question. If he doesn't know what I'm talking about, I'm going to kill him! She thought nervously, clenching her fists. Either he saw the look on her face or he had just been still too sleepy to think clearly when she first asked the question, she couldn't figure out which, but he quickly straightened up and changed his tone, uttering, "Oh! ... right...yeah....uhhh..."
"Looks like you two are having fun," Aang said, walking in at that point, "Are you ready to leave?"
Sokka replied that he wasn't yet, and walked back over to pick up his sleeping bag. The head of the Jiandan household having just arisen, Aang walked over and bowed before him, thanking him and his family for their hospitality. The three of them walked out of the doorway and over to the place just outside the barn where Aang had moved Appa to. They clambered aboard, Toph briefly thinking that she might hold onto Sokka's arm for support during the flight instead of the saddle's handles as a purposeful display of affection toward him, but then deciding against it because she did not want to give Aang any more reasons to be suspicious than he already had.
They flew southward until the heat of the air indicated that it was midday, at which point they finally landed to take their lunch break. She heard Sokka jump out of the saddle, and then was surprised when he unwound her arm from the handle and tried to guide her out of the saddle; unable to decide if she ought to resist it as a threat to her dignity or if doing this would be potentially damaging to the possibility of them being together, Toph grimaced uneasily but ended up letting him help her to the ground without much complaint. From Aang's silence immediately afterwards, she knew that he was growing more suspicious, but could find no way to fix that problem without also creating more problems for her being with Sokka. I still don't know if he meant what I thought he did last night...
Aang started a fire going in what Toph soon realized was a clearing in the middle of a conifer forest. While he began cooking up some sort of soup for the three of them over the fire, Toph walked off a ways to practice her Earthbending in order to calm her nerves, which were quite on edge by that point. Fifteen minutes later, he called her back over and handed out to his friends in wooden bowls they had brought along for that purpose. Sokka ate about half of his, and then stated that he wasn't feeling very hungry that day; Toph scooted from where she had been sitting a quarter way around the circle from him, and sat with her arm pressed directly up against his, taking the bowl out of his hands and started scarfing it down, the unusual on-going anxiety she had been experiencing all day making her feel ravenously hungry.
Toph could tell Aang was feeling confused about Sokka's change of appetite, so she tried to draw his attention away from it by asking about the adventures he had had since she had went to live at the Southern Water Tribe. He eagerly dived into the subject, telling the two of them about all the places he had went and the people he had helped, but was interrupted by Sokka, who had apparently been reminded about his lost space-sword and began complaining about the difficulty of contacting Piandao in order to make a new one. She suggested that he ask Iroh to use his White Lotus connections to get a hold of Sokka's old sword's-master, and then Sokka eagerly began chatting away about the metals he might use if the meteorite had been disposed of in the past six years, and how he would one day become a good enough sword's-master that even Zuko wouldn't be able to best him in a match. Toph secretly doubted that, but she tried to be polite and take interest in the subject anyways, thinking about what she might be able to do while Metalbending the substances he was describing. Apparently she came off as too polite (for her, anyways), because she felt Aang becoming suspicious again, and was quite relieved a few minutes when he told them that they should hop aboard Appa again.
They flew onward until most of the day had passed away. Sokka's appetite seemed to have come back by then, and she heard him moving elsewhere in the saddle, muttering about food. After a few minutes, he announced tersely, "Out of meat."
Aang, apparently spotting a nearby village below them, called back to them from his position somewhere on Appa's head, "We can stock up on food supplies down there. I guess we might as well find a place to sleep there, too."
They landed right outside the entrance to the large town, and its citizens quickly found a place for the Avatar's sky bison in the town's mostly vacant ostrich-horse stable. His bison taken care of, Aang wandered off, telling them he would take care of the groceries. The two took a different path and looked elsewhere for an inn to stay at that night, and with some difficulty finally located the inn known as the Bu Shufu Di Difang. Toph's fame as the heroine of the Second Battle of Kyoshi apparently having not reached this cloistered village, they went unrecognized, and their claim that they were friends of the Avatar was similarly deemed unbelievable. Sokka reluctantly ended up having to pay for a three-person room for the group, which they were then directed to by the host.
When they were left alone in the room, an awkward silence came upon them and lasted several minutes. Sokka was the first to break the spell, "This is just getting way too weird."
"Yeah, it has," she agreed simply, not knowing what else to say.
Sokka shook his head, "I can't believe I can't stay in this room alone with you... We've got to do something to shake the craziness off our backs."
"Like what?" Is that even possible?
Sokka appeared to ponder the question for a bit, and then snapped his fingers, having gotten an idea. "Oo-oo! I know! We can fly around on Appa...like we're on another mission again."
Catching onto his intent very quickly, Toph felt relieved that she wasn't the only one longing for things to be like they used to. She got it in her head that she ought to show her pleasure at his idea by kissing him on the cheek, but the feeling went away as soon as she did so, leaving her to feeling very self-conscious right afterwards.
Sokka seemed taken aback for a few seconds, but then she felt him shake his head and walk out the door to their room, motioning for her to follow him. They made their way to Appa's stable, and, since Aang had already removed his saddle earlier, they climbed up onto his head, not wanting leave evidence behind by disturbing anything. Toph had qualms about being in such a potentially dangerous situation while flying blind, but Sokka allowed her to loop her left arm around his right one in order to support herself; she told herself that this was absolutely needed for her own safety and that it would in no way interfere with the non-romantic intent behind their little trip, repressing from her conscious view the obvious fact that there would have been no reason to hide what they were doing if this were actually the case.
From her precarious position on Appa's head, Toph gritted her teeth a bit at the rush of air produced by Appa's take-off, her bangs finally coming loose from where Sokka had brushed them back the night before (which she had left in place most of the day in order to avoid arousing Aang's suspicions even more). Leaning back against Appa's body and closing her unused eyes, she soon grew used to the air blowing against her face, which enabled her to imagine that she was a twelve-year old again, adventuring across the globe on a mission to save the world. Her inability to see anything merely helped her to ignore the present, and indulge herself in happy memories. From his silence, she guessed that Sokka was doing something similar.
Her discomfort at being next to him finally disappearing, Toph snuggled up closer to him and asked something that had been on her mind all day, "So...are we together now?" She had feared the answer she might get ever since their kiss the night before.
Sokka immediately put her at ease by putting his arm around her shoulders, and answered, "Yeah...I guess we kinda are," sounding like he was surprised but not displeased by the fact. She breathed a sigh of relief.
The knots which had been tightening in her stomach all day began to unwind as she sat nestled up against him. Overjoyed at the news that she need not fear them being separated by his rejection any longer, and exhilarated by the feeling that she was completely safe with him in the air despite not being able to see, Toph found it easy at that moment to ignore the world around her and leaned in closer to Sokka to kiss her new-found boyfriend on the cheek, without a worry in the world.
She rested up against his side, feeling content. They began chatting back and forth about the strangeness of the past couple of days, unburdening themselves mentally by viewing them from afar in this way. Time flew by quicker than Appa, and Toph soon guessed from the movements of his arm that he had grasped Appa's reigns tightly again in order to change the bison's direction, the wind in her face telling her they were headed towards the ground. As an explanation, Sokka offered the comment, "We'd better get Appa back into the barn before Aang notices." Toph understood his point completely.
Toph loosed her arm from Sokka's when they landed, and jumped back onto the ground on her own. She felt Sokka landed on the other side of Appa's head, and the two of them guided Appa by the horns back into the place where they had found him. Sokka made a joke about how bad Appa still smelled, and Toph punched him in the arm, telling him cheerfully how unfunny his joke was. Judging from the vibrations he gave off, Toph guessed he was happily grinning from ear to ear, and they both chuckled a little bit out of a sense of relief about things being back to normal again between the two of them. Sokka grabbed her hand, and she allowed him to lead her out of the stable.
She soon realized that she had been having too much fun to pay the proper amount of attention to her surroundings when the pair almost ran smack into Aang right outside the stable's doorway. Her back instantly stiffened up a bit out of nervousness. "Uh...hi, Twinkle-To-oes," she said in an attempt to sound nonchalant, stuttering a little bit on the last syllable.
"Hi, Toph. What were you two just doing with Appa?" he asked, seeming to be eyeing their hands.
"We were just ..." Toph began, unable to come up with a good explanation. The non-romantic nature of the trip had seemed a lot more convincing when it was just them two alone.
"Why are you acting so nervous?"
Sokka seemed to have steady himself on his legs before he answered matter-of-factly, "We were just taking a mini-trip on Appa to calm ourselves down after the long day we had today." Thank you, Sokka! She thought with relief that he had managed to make their trip seem perfectly ordinary.
"Ohhh-kaaay," Aang said slowly, seeming to take this in, and clearly not believing this was the whole story. Much to Toph's relief, he did not press the question further despite obviously being suspicious, and they walked back to the Bu Shufu Di Difang in silence.
After passing the host of the hotel (who seemed embarrassed to realize they really were friends of the Avatar), they walked back to their joint room. Once the three of them had piled in, Sokka decided to leave again to find a bathroom, leaving Toph alone with Aang. Toph felt Aang turn to face her, and she winced internally about the subject she knew he would now bring up.
"What was going on with you and Sokka back there?"
"What do you mean, Twinkle-Toes?" she replied, trying to sound as if she had absolutely no idea what he was talking about.
"Let's see...you two were just holding hands, you were wearing your hair out of your face earlier (which you never take the time do), you didn't stop Sokka from helping you off of Appa earlier..." Aang sounded like he was counting off the evidence that something was up on his fingers.
"Shut up, or I'll punch you!" Toph ordered as she waved her fist around wildly, beginning to fear that he would figure things out.
"You've been acting nervous all day, Sokka wasn't hungry for lunch," Aang went on, unfazed by her threat. "And now you're trying to hide what you were doing with my bison. Something is up."
"Okay, okay, okay," Toph said quickly, trying to catch up with him mentally in order to come out of his interrogation with some dignity. Unable to avoid the question any longer, she simply gave him a straightforward answer, "Sokka and I kissed last night." She clenched her fists in case he found their situation comical.
Even though he had been acting suspicious, Toph felt Aang jump off the ground in surprise at the present news. "Wow," he said simply, sounding as if he didn't know how to take it. There were a few moments of silence before he added, "How'd that happen?"
"I have no idea."
"So...you two are together now?" he asked, sounding very confused.
There was silence as he seemed to be pondering the subject, and then he said aloud, "I wonder what Katara will think of this."
What will she think? Toph thought, the question registering in her mind for the first time since their moonlit kiss the night before. Then she realized something with a start, smacking herself in the forehead for not realizing it sooner, "Oh man, this is going to look really weird, Twinkle-Toes."
"It's just...Sokka left the South Pole to woo Suki back, and now..." she trailed off, letting the Aang's mind to fill in the blanks.
"You're right," Aang realized. He seemed to start to say something, but Sokka waltzed back into the room at this point and he trailed off. The Water Tribe member asked them, obviously oblivious to the situation, asked them both nonchalantly with no forcedness, "What's up?"
"I just made Toph tell me why you two were acting so weird," Aang answered
"Oh," Sokka reacted by jerking his head back a bit in surprise. Aang went on to explain about the situation they were probably going to have with the whole matter of Suki (Sokka wincing when he first heard the name of his engaged former girlfriend) and Toph, which took awhile to get through Sokka's thick skull.
When he finally understood, Sokka smacked himself in the forehead. "I knew I should have sent a message back earlier!" He shook his head, resigning himself, and went on, "Well, I guess we can't really do anything about that now. We'll just have to face it."
"I'll write a letter to from me telling them about what happened with Suki, if you want," Aang spoke up, trying to not to tread on anyone's feelings. "You better explain this in person, though; I have no idea what's going on between you two anymore."
Sokka readily agreed to Aang's plan, and they decided to send the message whenever Hawky came back from delivering the news about Long Feng to South Pole. The matter settled, and with the relationship between Toph and Sokka in the open air, the three friends finally began to be able to speak comfortably with one another again about (unrelated) events which had recently gone on in their lives. Her mind finally at relative peace, the only reason Toph had difficulty going to sleep that night was because the beds in the room were deceptively lumpier than they seemed to be when they had first been given the room. I am never coming back to this place, she thought to herself as she finally drifted off to sleep.
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Kindle Publishing and Crystals for Business TPS228
Podcast: Play in new window | Download (15.8MB)
Subscribe: Apple Podcasts | Android | RSS
In today's episode I recap what happened and what I learned from my Kindle launch. I also talk about using crystals and minerals to help you build and improve your business.
- Bottom line: if you publish on Kindle and do it yourself, it isn't easy to actually sell books.
- The people who make a lot of money with Kindle have a team of people helping them.
- The book, The Search for Connection, is the story of when I gave everything away and went wandering.
- In the book, I talk about the energy healing I did and my crystal business.
- I see that the interest in crystals is really expanding now.
- With energy healing you can feel great right away, but it can take months to feel the full effect.
- When it comes to choosing a crystal, use your intuition. Find one you like and use it the way you feel is right for you.
- You won't always know why you feel good when you hold a crystal, stone or mineral specimen. You don't need to.
- On ToolsForProsperousLiving.com, you can see what I'm offering now.
- I talk about how I got the urge to look into cinnabar.
- My power stone is a ruby.
- Don't think that crystals and minerals create miracles.
- Quartz has the ability to transmit and amplify electromagnetic energy. Your body-mine is an electromagnetic machine. So quartz helps you tune into the deeper parts of yourself.
- Your body has many minerals. Bringing minerals into your energy field stimulates the minerals in your body.
- Keep a quartz cluster on your desk and you'll be able to tune into your clients more easily.
How to Become a Best-Selling Author on Amazon Kindle (Use this link for 25% off)
See my crystals and stones at www.ToolsForProsperousLiving.com
My new book, The Search for Connection, on Amazon


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What is JotForm?
JotForm is a free online form builder which helps you create online forms without writing a single line of code. No sign-up required.
At JotForm, we want to make sure that you're getting the online form builder help that you need. Our friendly customer support team is available 24/7.
We believe that if one user has a question, there could be more users who may have the same question. This is why many of our support forum threads are public and available to be searched and viewed. If you'd like help immediately, feel free to search for a similar question, or submit your question or concern.
Hide Columns in Submissions of Grid reportAsked by larryback on April 29, 2015 at 04:17 PM
Is there a way to permanently hide selected columns in the submissions or grid reports? I can uncheck the boxes, but then when I close and re-open the reports, those fields are restored.
At the present the grid columns cannot be hidden permanently from the browser, the grid is dynamically generated every-time the browser is refreshed
Thanks, Sammy. How is it that I was able to hide the Submission Date field on this grid report: http://www.jotform.com/grid/51176461151045, but not this one:
JotForm Support
As I check the grid report for your JotForm titled "Report Card - Personal, Professional, Auto Services", I see that Submission Date is checked.
You may uncheck the fields that are not required from the report by clicking on Edit button and save the report.
You may also try generating a new Grid report for your JotForm. Hope this information helps.
Thanks, Kiran. That's very instructive. Creating a new grid report worked.
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That's great!! We are glad to see that the issue is now resolved for you. Please do not hesitate to get back to us if you need any further assistance. We will be happy to help.
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Home / Hire Us
As well as supporting the efforts of individual craftivists around the world, the Craftivist Collective also provides professional services to commercial and not-for-profit organisations.
We can help with craftivism consultancy, workshops, delivering talks and project or event management.
Get in touch to discuss your requirements and how we can help you with a touch of craftivism.
Our founder Sarah Corbett is available for speaking engagements in the UK and abroad as required. She is a passionate and inspirational speaker, who has delivered guest lectures, seminars and tutorials at the prestigious Parsons News School (NYC), Bauhaus University and Helsinki University amongst others and mentored many students. Sarah has also appeared as a guest on panel Q&As including British Library amongst others and chaired Twitter debates for organisations, been on live radio, recorded podcasts and event French and Italian TV. She has spoken at a variety of different events including campaigning conferences, festivals, and two different TEDxTalks. You can see some of her public speaking below:
Lost Lecture: Founder Sarah Corbett delivering a 15 minute talk at Battersea Arts Centre to a sold out crowd of 500 people as part of the Lost Lecture programme.
If you would like to add an element of practical craftivism to your event, Craftivist Collective is able to provide bespoke workshops or events to suit your needs. We've previously created workshops for V&A Museum that brought in 150 people at each of her four drop-in workshops, Secret Cinema (5 weeks, reaching 5000 people!), William Morris Gallery and more, to deliver successful workshops to groups, both large and small.
If you would like help creating a craftivism project or include an element in your workplace or project Craftivist Collective is able to offer training in how to create and deliver craftivism projects for different briefs or create and deliver the projects for you. We have worked with many organisations such as Etsy, The Climate Coalition, Ben and Jerrys, Craftspace and others. See endorsements on Linkedin here.
We can provide speakers, consultants and facilitators.


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Search Collections
glass Smithsonian American Art Museum Gift of John Gellatly
Smithsonian American Art Museum
Luce Foundation Center, 4th Floor, 52A
Luce Center Label
Most of the glass vessels in this case date from the first century BC to the fourth century AD. Early glass vessels were made in the Middle East and Egypt using the core-forming technique, in which molten glass was poured over a clay core and decorated with threads of colored glass. During the first century AD, Rome became the center of glassmaking, and the invention of blown glass led to new methods, including free-blown glass, which could be decorated by pinching, rolling, or dragging the surface, and mold-blown glass, in which the molten glass was blown into a terra-cotta mold. The Romans also developed stratified glass, in which different colored canes were fused together and blown [see 19188.8.131.52, 19220.127.116.11], and millefiori glass (Italian for "one-thousand flowers"), in which colored strips of glass were joined together into a rod, cut into slices, and fused into bowls and cups [see 19188.8.131.52, 19184.108.40.206]. Many glass vessels were buried in the tombs of wealthy Romans and this contact with damp soil over hundreds of years caused the surface of the glass to deteriorate and become iridescent [see 1922.214.171.124, 19188.8.131.52].
decorative arts - glass
About Unidentified
More works in the collection by
Blogs, Podcasts, and More
- Eye Level: Conversation Piece: Martin Puryear's Vessel
- Eye Level: The Clay's the Thing
- Eye Level: Lino Tagliapietra: Wedded to Glass
- Eye Level: Five Questions for Basket Collectors Martha Ware ...
- Eye Level: Luce Artist Talk with Soomin Ham
- Eye Level: American Art Education
- Eye Level: We've Got Something for You at the Renwick This ...
- Webcast
- Eye Level: Luce Artist Talk: Five Questions with Anne Bouie
- Eye Level: All the (Craft) World's a Stage


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What is JotForm?
JotForm is a free online form builder which helps you create online forms without writing a single line of code. No sign-up required.
At JotForm, we want to make sure that you're getting the online form builder help that you need. Our friendly customer support team is available 24/7.
We believe that if one user has a question, there could be more users who may have the same question. This is why many of our support forum threads are public and available to be searched and viewed. If you'd like help immediately, feel free to search for a similar question, or submit your question or concern.
Referral Link to get more submissionsAsked by selvecchio85 on February 05, 2015 at 01:26 PM
Is there a referral Link I can just copy and give to someone without having to enter their email address?
JotForm Support
I am sorry that I didn't get what referral link you are referring to. Could you please elaborate on this so that we can guide you in the right direction.
We will wait for your response. Thanks!
When I go here: http://www.jotform.com/myaccount/getMore there are all kinds of options to increase my limits except an actual referral link that I can copy and paste into a forum thread. I'm currently having a discussion in a group online and providing information on the how they can utilize JotForm, but I need a URL to provide them that will add to my submissions when they sign up.
JotForm Support
Unfortunately, the referral links are not yet made available. This may be the feature that we implement in the future. However, you may write a review about JotForm one any of your websites/blogs to get your submissions increased subject to approval. We appreciate your active participation in reviewing JotForm.
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INDIA: Toyota to set up automatic transmission production centre - report
Toyota Motor Corporation will build an export-oriented automatic transmission manufacturing facility in Karnataka, at its Qualis utility vehicle manufacturing facility near Bangalore, India#;s Financial Express newspaper reported on its website. The newspaper said that a high level committee of the state government has cleared the proposal and cited Karnataka#;s large and medium industries minister RV Deshpande as saying that the project would start commercial production in 2004 with trial production due by the end of next year.
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