text:
|Publication number
|Publication type
|Application number
|Publication date
|Oct 23, 2007
|Filing date
|Sep 29, 2003
|Priority date
|May 19, 1999
|Fee status
|Also published as
|Publication number
|Alan R. Rapacki, Dean F. Carson, A. Adam Sharkawy
|Original Assignee
|Medtronic, Inc.
|Export Citation
|BiBTeX, EndNote, RefMan
|Patent Citations (59), Referenced by (5), Classifications (17), Legal Events (5)
|External Links: USPTO, USPTO Assignment, Espacenet
This application is a divisional of U.S. patent application Ser. No. 09/314,119, filed May 19, 1999 now U.S. Pat. No. 7,075,937.
1. Field of the Invention
The invention relates to methods and devices for manufacturing a conduit for placing a target vessel in fluid communication with a source of blood, and more particularly placing a coronary vessel in fluid communication with a heart chamber containing blood.
2. Description of Related Art
Despite the considerable advances that have been realized in cardiology and cardiovascular surgery, heart disease remains the leading cause of death throughout much of the world. Coronary artery disease, or arteriosclerosis, is the single leading cause of death in the United States today. As a result, those in the cardiovascular field continue to search for new and improved treatments.
Coronary artery disease is currently treated by interventional procedures such as percutaneous transluminal coronary angioplasty (PTCA), coronary stenting and atherectomy, as well as surgical procedures including coronary artery bypass grafting (CABG). The goal of these procedures is to reestablish or improve blood flow through occluded (or partially occluded) coronary arteries, and is accomplished, for example, by enlarging the blood flow lumen of the artery or forming a bypass that allows blood to circumvent the occlusion. What procedure(s) is used typically depends on the severity and location of the blockage(s). When successful, these procedures restore blood flow to myocardial tissue that had not been sufficiently perfused due to the occlusion.
An alternative, recently proposed treatment places the target vessel in fluid communication with a heart chamber containing blood, for example, the left ventricle. Blood flows from the ventricle into a conduit that is in fluid communication with the target vessel. Some of the challenges associated with these procedures include delivering and deploying the conduit in the patient's body, and in particular properly positioning the conduit with respect to the heart chamber and the target vessel.
The continued improvement and refinement of existing treatments and the search for new treatments are indicative of the significant effort that continues to be expended in order to develop better and more efficient ways of revascularizing the heart.
Accordingly, there is a need in the art for improved methods and devices that are capable of being used quickly, easily and in a repeatable manner to carry out cardiac revascularization successfully and economically. Consequently, there is a need in the art for methods and devices for manufacturing conduits that will meet one or more of these needs.
According to one embodiment of the invention, methods and devices are provided for manufacturing a conduit for use in placing a target vessel in fluid communication with a source of blood. One method includes steps of providing a biocompatible material suitable for use in delivering blood, and forming the biocompatible material into a conduit comprising first and second portions disposed transverse to each other and having lumens in fluid communication. The first conduit portion is formed with at least one inlet configured to be positioned in fluid communication with a heart chamber containing blood, and at least a part of the first conduit portion has sufficient rigidity to prevent collapse during myocardial contraction when disposed in or secured to myocardial tissue. The second conduit portion is formed with at least one outlet configured to be placed at least partially within the lumen of a target vessel in fluid communication with the vessel, and at least a part of the second conduit portion has sufficient resiliency to allow the second conduit portion to substantially conform to the contour of the target vessel.
Another method includes steps of providing a mold having a cavity configured to form a conduit including first and second portions disposed transverse to each other, wherein a conduit corresponding to the cavity is suitable for use in placing a source of blood in fluid communication with the lumen of a target vessel, placing a biocompatible moldable material in the mold cavity, subjecting the material to conditions that mold the material into a conduit having a desired configuration, and separating the mold and the conduit.
Another method includes step of providing a mold having a cavity including first and second portions disposed transverse to each other, positioning a mandrel in the mold cavity, the mandrel having first and second portions substantially corresponding to the first and second portions of the mold cavity, and forcing a moldable material into the mold cavity and around the first and second portions of the mandrel into the first and second portions of the mold cavity. The method further includes subjecting the material to conditions sufficient to set the material in a desired configuration, removing the mandrel from the mold, and separating the mandrel and the material to produce a conduit comprising first and second portions that are disposed transverse to each other and have lumens in fluid communication with each other.
Another method includes steps providing a mandrel including first and second portions disposed transverse to each other, the first and second portions of the mandrel defining at least one external surface corresponding to an interior surface of a desired conduit configuration, disposing a biocompatible moldable material on the external surface of the mandrel, subjecting the material to conditions that mold the material into a conduit having the desired configuration, and separating the conduit from the mandrel.
Still another method includes steps of forming biocompatible material into a conduit comprising first and second portions disposed transverse to each other and having lumens in fluid communication, forming the first conduit portion with at least one inlet configured to be placed in fluid communication with a heart chamber containing blood, and providing at least a part of the first conduit portion with sufficient rigidity to prevent collapse during myocardial contraction when disposed in or secured to myocardial tissue. The second conduit portion is formed with at least one outlet configured to be placed at least partially within the lumen of a target vessel in fluid communication with the vessel, and this step is carried out so as to form the first conduit portion with a full tubular configuration that extends substantially 360� in cross-section, and the second conduit portion with a partial tubular configuration that extends less than 360� in cross-section.
A mold constructed according to the invention includes a base defining a mold cavity, wherein the mold cavity has first and second portions configured to form a conduit including first and second portions, and wherein the first and second portions of the mold cavity are disposed transverse to each other to form a conduit with first and second conduit portions in fluid communication with each other and adapted to place the lumen of a target vessel in fluid communication with a heart chamber containing blood.
Another method according to the invention includes steps of providing first and second hollow members each of which has a lumen, forming an opening that extends into the lumen of the first hollow member, positioning one of the first and second ends of the second hollow member adjacent the opening in the first hollow member, and joining the one end of the second hollow member to the first hollow member with the lumens of the first and second hollow members sealed together in fluid communication.
The invention will be better understood from the following detailed description of preferred embodiments thereof, taken in conjunction with the accompanying drawing figures, wherein:
The present invention provides methods and devices for manufacturing a conduit that is placed in a patient's body to establish a flow path between a source of blood and a target vessel of the patient's vascular system. In a preferred application, the source of blood is a heart chamber containing oxygenated blood and the target vessel is a coronary artery or vein. It will be recognized, however, that the conduit may be used to form a blood flow path between other hollow body structures. Also, as used herein, source of blood refers to any blood-containing structure, while oxygenated blood refers to blood containing some level of oxygen. The conduit may be used to bypass a partial or complete occlusion in the target vessel; alternatively or additionally, the conduit may be used to supplement blood flow (native or other) that is already present in the target vessel.
The Figures show several conduit configurations in order to describe various aspects of exemplary embodiments of the present invention. It will be recognized, though, that these conduits represent only a few of the numerous constructions that may be manufactured according to the principles of the invention. For example, the conduit may be manufactured so as to have any of the constructions described in co-pending, commonly owned application Ser. No. 10/778,723, filed Sep. 10, 1999, and entitled "Conduits For Use in Placing a Target Vessel in Fluid Communication With a Source of Blood," the entire subject matter of which is incorporated herein by reference.
In its most preferred form, the conduit of the invention include a first conduit portion having at least one inlet adapted to be placed in communication with a source of blood and a second portion having at least one outlet adapted to be placed in communication with the lumen of a target vessel. The first and second conduit portions may be defined by a single unitary member or several members that are attached or formed into a desired configuration. The first and second conduit portions are transverse to each other and have lumens that meet at a junction. For example, the first and second conduit portions have respective axes that extend transversely to each other to form a predetermined angle, the angle preferably being within a desired range that achieves acceptable flow characteristics.
The conduit 10 is generally T-shaped with the first and second conduit portions 12, 14 meeting at a junction 20 such that their respective axes a, b are substantially perpendicular. It should be noted, though, that according to the invention the axes a, b of the first and second conduit portions 12, 14 could be disposed non-perpendicularly. For example, rather than forming a 90� (or substantially 90�) angle, the axes a, b could extend transversely to each other to form an acute or obtuse angle (depending on which side the angle is measured with respect to axis a in
The first conduit portion 12 has a free end 22 defining the inlet 16 while the second conduit portion 14 has a pair of free ends 24 defining the outlets 18. The free ends 22, 24 may be integral extensions of their respective conduit portions or they may comprise separate members secured to the conduit. One or more of the free ends 22, 24 may be beveled (or otherwise configured) for easier introduction into the target vessel. The ends 22, 24 of the conduit portions 12, 14 are preferably formed of a flexible, relatively atraumatic material that will not damage the endothelial cells lining the intimal surface of the target vessel, particularly during placement of the device.
The conduit inlet 16 or outlets 18 may be located at positions other than those shown in the Figures, e.g., at one or more points along the length of the conduit. Similarly, in the illustrated embodiment the first conduit portion 12 (axis a) is offset in that it does not bisect the second conduit portion 14 (axis b); this provides the second conduit portion with different size legs extending away from the first conduit portion. Configuring the target vessel portion of the conduit 10 with shorter and longer legs may be useful in introducing the conduit into the target vessel. It should nonetheless be recognized that the first conduit portion 12 may be centrally located along the axis b of the second conduit portion 14 to provide legs of equal length, or it may be offset from the axis b a greater distance than shown in
According to one preferred embodiment, the methods and devices of the invention are used to form a conduit that is provided with a reinforcing component having sufficient strength to ensure that the conduit remains open during use by preventing or reducing the likelihood of the conduit kinking or collapsing. The reinforcing component may be integrally formed with the conduit or it may comprise a separate member secured thereto. One embodiment of a reinforcing component 26 is shown in
In the illustrated embodiment, the spacing, as well as the size and material of construction, of the coils 28 may be used to determine the amount of structural support provided by the reinforcing component 26. As such, these variables may be selected to produce a conduit having desired characteristics. For example, one of the first and second conduit portions 12, 14 may be made more rigid or flexible than the other by varying the pitch of the coils, the thickness of the wire forming the coils, the material forming the coils, etc., on the portions. Further, the reinforcing component 26 may comprise a single coil, a first coil for the first conduit portion and a second coil for the second conduit portion, a first coil for the first conduit portion and two separate coils for the two free legs of the second conduit portion, etc. Finally, it will be noted that the reinforcing component may have a non-coiled configuration, e.g., a stent or stent-like construction, and may comprise a single member or a plurality of discrete members.
The second conduit portion 14 is relatively flexible to allow it to yield slightly and follow the contour of the target vessel (not shown) while being placed therein. The first conduit portion 12 may be more rigid than the second conduit portion 14, particularly if the blood source is a heart chamber and the first conduit portion 12 is placed in (or secured to) myocardial tissue. In this case, the first conduit portion 12 would preferably be relatively rigid to remain open during myocardial contraction. The junction 20 of the first and second conduit portions 12, 14 is essentially unreinforced in the embodiment shown in
Whereas the conduit 10 (without the reinforcing component 26) is formed of one piece of material, the conduit 30 shown in
As described further below, the first conduit portion 32 of this embodiment has an opposite end 46 which is bifurcated into two flaps 48 each of which is secured to the conduit portion 34 by any suitable means. The edges of the flaps 48 may be tapered or feathered (as shown) to make a smooth transition with the exterior of the second conduit portion 34, thereby minimizing the amount of material to be introduced into the lumen of the target vessel. It also may be preferable to minimize the wall thickness of the material used to form the conduit to further reduce the amount of material that must be accommodated in the target vessel lumen, without sacrificing preferential blood flow characteristics or the structural integrity of the conduit.
The illustrated conduit 30 may include a reinforcing component such as 26 that is coupled to or formed with the body of the conduit. Attentively, as shown in phantom in
An exemplary manner in which the conduits of the invention may be used to establish a blood flow path between a target vessel and a source of blood will be explained briefly with respect to
The second conduit portion 54 includes two outlets 58 placed in the lumen of the LAD through an incision I; in the illustrated embodiment, the conduit portion 54 is secured in place by suture S. The second conduit portion 54 will typically be placed in the target vessel distal to the occlusion by a distance that permits easier introduction into the lumen, as opposed to entering a diseased or stenosed section of the vessel. This results in a space located between the occlusion O and the conduit outlet 58 that is disposed nearest the occlusion (the outlet to the left in
Accordingly, as explained in the aforementioned co-pending application, the conduits of the invention are preferably configured to deliver blood into the target vessel in multiple directions to fully revascularize the myocardial tissue perfused by the vessel. As shown in
It will be appreciated that the size of the conduit and thus the methods and for manufacturing the conduits will vary depending on the application. In short, each conduit portion has a length, a diameter (or a different dimension if the cross-section is non-circular) and a wall thickness, and the methods and devices of the invention may be utilized and modified to control one or more of these dimensions, for example, to obtain desired flow characteristics or adapt the conduit to a given application.
The conduit is preferably sized and configured to form a blood flow path that is equal or substantially equal, in volume of blood carried, to the blood flow path defined by the native vessel. In other words, the conduit preferably defines an inner diameter that equals or substantially equals the inner diameter of the native vessel. As a result, when placed in the target vessel the conduit allows a sufficient volume of blood to flow through the target vessel. If the target vessel is a coronary artery, this ensures that blood will flow to the distal vasculature and perfuse the myocardial tissue. Some preferred materials of construction as well as ranges for various dimensions of the conduits are provided in the aforementioned, co-pending application Ser. 10/778,723 entitled "Conduits For Use in Placing a Target Vessel in Fluid Communication With a Source of Blood".
Referring now to
The first and second portions 90, 92 of each mold cavity 88 are preferably provided with one or more channels 94 to vent air and allow excess molding material to flow out of the mold 80. Each mold cavity 88 also has an inlet 96 into which moldable material is injected, the inlet 96 being tapered or necked down at an area 98 communicating with the second portion 92 of the cavity 88. See
The mandrel 86 has first and second portions 100, 102 which are received in the first and second portions 90, 92 of each mold cavity 88. More specifically, in addition to the mold cavity 88, each mold half 82 includes a groove 104 for receiving part of the first mandrel portion 100, and a pair of grooves 106 for receiving part of the second mandrel portion 102. The grooves 104, 106 extend from the mold cavity portions 90, 92 and are sized to receive part of the respective mandrel portions 100, 102 in surface-to-surface contact when the mold 80 is assembled. The portions 90, 92, in contrast, are larger than the mandrel portions 100, 102 and grooves 104, 106, as described below regarding FIGS. 15 and 15A-15C. As a result, when the mandrel 86 is placed in the mold 80, an annular space is defined between the mandrel portions 100, 102 and the cavity portions 90, 92 to receive the moldable material.
The mold 80 is then subjected to suitable conditions, for example, maintained at a predetermined temperature for a sufficient amount of time, in order to set the material M in the desired configuration. Upon completion of this step, the mold halves 82 are separated, as shown in
According to a preferred embodiment of the invention, though, the preform 118, prior to final processing, is provided with a reinforcing component to add a desired amount of rigidity to prevent or reduce the likelihood of the conduit collapsing or kinking during use.
The material M is injected and flows around the preform 118 and the reinforcing component 124 (omitted from
Referring to
Turning now to
In the illustrated embodiment, prior to placing the flaps 186 of the hollow member 160 against the member 162, a suitable adhesive (indicated schematically at 190 in
The conduit 192 is ready to be subjected to final processing, for example, trimming or removing any excess material from the conduit and applying any desired coating(s) to the conduit portions, such as anti-thrombogenic or anti-bacterial coatings. The conduit is then ready for packaging and sterilization, for instance, by placing the conduit in a Tyvek pouch the is subjected to ethylene oxide or gamma radiation sterilization. The finished conduit is sterile and ready to be used as a blood delivery device during a cardiovascular procedure.
Avoiding or minimizing contact with the posterior wall is beneficial as it reduces the risk of dislodging stenotic material or otherwise damaging the vessel. However, as shown in
The material may be removed by any suitable process, which will depend at least in part on the conduit material. For example, if the conduit, and in particular the second portion of the conduit, is formed of a relatively high durometer material, the process may comprise micro-abrasive media ablation techniques. It will be recognized that the procedure used to remove a desired amount of the material will depend at least in part on the specific material being used.
It will be recognized that the illustrated injection and dip-molding procedures are exemplary only in that other molding procedures may be used to form the conduit. As an example, a suitable rotational molding process may be used to manufacture conduits according to the invention. Other molding processes may of course be used as well.
The methods and devices of the invention have been used to produce various types of conduits that have been implanted in animals and have successfully delivered blood from a source to a target vessel. In the animal studies the source of blood was the left ventricle and the target vessel was a coronary artery. Three examples are presented below.
A first mold including two mold halves was machined from aluminum and had a configuration substantially the same as that shown in
A light coating of spray-on mold release was applied to the mandrel, and the mandrel was placed in the mold halves which were then assembled. Silicone was used as the moldable material. Air was removed from the silicone by vacuum and ultrasonic agitation prior to injecting the silicone into the mold cavity. Next, approximately one cc of NuSil Med-4950 silicone was poured into the inlet of the mold to form the conduit preform (as this conduit included a reinforcing component), and a plunger was used to force the material further into the mold inlet. Air was removed from the mold by applying a vacuum, and then the plunger was used to further force the silicone into the mold cavity.
The silicone was cured by heating the mold to 150� C. for 1 hour. The mold cooled and the halves separated after trimming the excess material from the gates. The mandrel and molded conduit were removed and washed with water and alcohol and then allowed to dry. Next, a reinforcing component was added. Nitinol coils were prepared with both left and right-hand pitch directions for the different conduit portions from a length of nitinol wire. A first right-hand coil was wrapped around the first conduit portion and a second right-hand coil was wrapped around one leg of the second conduit portion, at the same pitch. A similarly sized left-hand coil was wrapped around the other leg of the second conduit portion at the same pitch (with the outermost ends of the coils boxed with a smaller pitch). The two coils were wrapped around the second conduit portion with one turn extending across the junction.
Before wrapping the coils, NuSil Med-6210 silicone was applied to the preform to help secure the coils to the conduit, as shown by the embodiment of
A device for establishing flow communication with a heart chamber, such as the device 66 described above with respect to
Two tubular lengths of expanded PTFE (ePTFE) having a wall thickness of 0.008 inch and an internodal distance of 30 microns were formed substantially as the two conduit portions shown in
A reinforcing component was applied by wrapping a nitinol wire around the first and second conduit portions. The exterior surface of the conduit preform was coated with NuSil Med-4850 (LSR) silicone and the reinforcing wire was wrapped around the preform, embedding itself in the silicone. The silicone was then cured again in an oven at 150� for 1 hour. The resulting conduit included a layer of silicone over the coils of the reinforcing component to prevent their direct contact with animal tissue. The mandrels were disassembled and a device for communicating with a heart chamber was coupled to the first conduit portion. The device was then ready to be sterilized and placed in a target vessel of an animal heart.
It should be understood that reinforcing components, layers, etc., are preferred but not necessary, such components preferably taking the form of those disclosed in the aforementioned co-pending application 10/778,723. Also, if intended for use in an application with a heart chamber as the blood source, the conduit may be provided with a device for facilitating communication with the heart chamber, and preferably preventing or minimizing blockage of the conduit. Suitable devices are disclosed in disclosed in co-pending, commonly owned application Ser. No. 09/304,140, filed on May 3, 1999 and entitled "Methods and Devices for Placing a Conduit in Fluid Communication With a Target Vessel," the entire subject matter of which is incorporated herein by reference.
The conduits manufactured according to the invention may include a valve or other means for controlling or regulating blood flow. Suitable valves, as well as means for measuring myocardial thickness or verifying entry into the heart chamber, are disclosed in application Ser. No. 09/023,492, filed on Feb. 13, 1998, and entitled "Methods and Devices Providing Transmyocardial Blood Flow to the Arterial Vascular System of the Heart," the entire subject matter of which has been incorporated herein by reference. Likewise, the conduits may be provided with a reservoir for retaining and discharging blood in a desired manner.
The conduits of the invention may be manufactured as part of, or for coupling to, a conduit delivery device, such as that disclosed herein. The conduits and delivery devices manufactured according to the invention may be sized and configured differently from that specifically illustrated in the Figures. For instance, the cross-section of one or more portions of the conduit may be noncircular, e.g., elliptical, to better match the profile of the target vessel. As a further example, the delivery device may be relatively short with the shaft assembly substantially rigid for use in an open-chest procedure. Alternatively, the delivery device may be configured for use in either a minimally invasive or endovascular procedure, wherein the actuators for controlling the device components are located adjacent the proximal end of the device to allow remote deployment of the conduit, for example, as disclosed in the aforementioned, co-pending, commonly-owned application Ser. No. 09/304,140.
It will be appreciated that the features of the various embodiments of the invention may be used together or separately, while the manufacturing methods and devices disclosed herein may be modified or combined in whole or in part. As an example, more than one conduit may be formed as part of (or coupled to) a manifold that is placed in communication with one source of blood so as to deliver blood to multiple target vessels. The conduits and devices of the invention may include removable or detachable components, could be formed as disposable instruments, reusable instruments capable of being sterilized, or comprise a combination of disposable and reusable components.
Further, it will be understood that the invention may be used to manufacture conduits for use in specific types of medical procedures, for example, an open surgical procedure including a median sternotomy, a minimally invasive procedure utilizing one or more relatively small access openings or ports, or an endovascular procedure using peripheral access sites. Similarly, the conduits may be designed for use in beating heart procedures, stopped-heart procedures utilizing cardiopulmonary bypass (CPB), or procedures during which the heart is intermittently stopped and started.
The preferred embodiments of the invention are described above in detail for the purpose of setting forth a complete disclosure and for sake of explanation and clarity. It will be readily understood that the scope of the invention defined by the appended claims will encompass numerous changes and modifications.
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|U.S. Classification
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|International Classification
|Cooperative Classification
|European Classification
|Nov 10, 2004
Owner name: MEDTRONIC, INC., MINNESOTA
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:VENTRICA, INC.;REEL/FRAME:015366/0710
Effective date: 20041029
|Mar 23, 2011
|Fee payment
Year of fee payment: 4
|Jun 5, 2015
|Maintenance fee reminder mailed
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Effective date: 20151023


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subset: commoncrawl


text:
Olympics in Bangladesh
By: Nathan Miller and Kylee McMains
Physical Features:
Three Physical Features:
1. They have a lot of marshy jungles.
2. They are a low-lying riverine.
3. A lot of rainfall, high temperatures, and high humidity.
Tourists Attraction:
1. Ramana Park
2. Sonargaon
3. St. Martin's Island
Prices of Hotels:
1. The Westin Dhaka: $290 per night
2. Pan Pacific Sonargoan Dhaka: $144-$160 per night
3. Radisson Blu Garden Hotel Dhaka: $231 per night
Where to Eat:
1. Xinxian Restaurant Dhaka
2. Flambe Restaurant Dhaka
3. Star Kabab & Restaurant Dhaka
4. Fakruddin Biryani & Restaurant Dhaka
5. Spaghetti Jazz Dhaka
Where the Olympics Can Be:
1. Shere-e-Bangla National Cricket Stadium
2. Bangaabandhu National Stadium
3. Zahur Ahmed Chowdhury Stadium


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Palm Springs, Calif., has been a redoubt for snowbirds and show business royalty at least since the 1930s.
Under-40 Home Builders: Working the Market
Taber LeBlanc of Homes by Taber discusses the changes and challenges in the Oklahoma City market.
The recession battered many of the nation's largest housing markets, but Oklahoma City managed to avoid the brunt of the crash. Nonetheless, the downturn dented the sales volume of Homes by Taber, a company founded by Taber LeBlanc in 2000. While many builders eliminated amenities from their product to reduce costs and compete in the depressed market, LeBlanc retained the existing features in his homes and even incorporated more amenities such as cathedral ceilings and outdoor fireplaces to increase overall value. After adding as many sensible upgrades as possible, LeBlanc shifted the company's strategy toward improving energy efficiency.


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in plus sizes
in plus sizes
available in
extended sizes
extended sizes
- roll over image to zoom
Micro Ocean Reef Egg Paperweight
Art Glass Paperweight(ID: A32588)
Created by Michael EganLimited Edition
Mini version of Egan's classic Ocean Reef Egg paperweight. It is filled with undersea plant and animal like entities, all flowing and waving in an unseen current. Each one is unique and fun. Limited edition of 14.
Shipping Information
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Michael EganMicro Ocean Reef Egg Paperweight
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Comments about Micro Ocean Reef Egg Paperweight:
This glass paperweight draws the eye and would be the subject of many coversations on its beauty. It is breathtaking. I want my own.
- Was this a gift?:
- Yes


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With Halloween almost upon us, you might be wondering how you're going to decorate your house. Now, you could just go to the supermarket, and buy something. But where's the fun in that, when you can create your own, and make them extra-spooky by using a Raspberry Pi. Here are 7 you can make at home.
Much like our similar, Arduino-focused take from 2013 8 Amazing Halloween Frights You Can Make With An Arduino 8 Amazing Halloween Frights You Can Make With An Arduino Learning electronics with an Arduino is fun, but using one to scare the life out of trick-or-treating children is just downright heavenly. Read More , we're going to be ranking each one based on their spookiness factor, and how difficult they are to build.
The Spooky Porch
Scare Factor: 7/10
Complexity: Medium
Created by Cabe Attwell, The Spooky Porch uses the full capability of the Raspberry Pi B+'s GPIO to scare any unfortunate trick-or-treaters who pass by.
As someone approaches, it slowly brightens a series of blood-red lamps, whilst simultaneously dimming any porch lights, and playing some rather sinister, ethereal noises. When the visitor reaches the door, the track switches to something even more shocking.
The code, and all designs for this project are available to download from the Element14 website. As far as it goes, it's fairly straightforward to make, and well documented. Although it involves a lot of different, individual components, including six different flood lights, and a motion sensor.
Pumpkin Pi
Scare Factor: 4/10
Complexity: Easy
No porch on halloween is complete without a spooky, carved pumpkin face. But rather than simply stick a candle in yours, why not throw in a Raspberry Pi?
Designed by Brian Gillespie, the Pumpkin Pi does just that. Using a Raspberry Pi, a few lines of Python, a breakout board, and some LED's, he shows you how to turn a flickering Pumpkin into something that bit more scary.
Raspberry Pi Halloween Lights and Music Show
Scare Factor: 3/10
Complexity: Easy
Noel Portugal's Halloween Lights and Music Show is very similar in spirit to The Spooky Porch, in the respect that it uses lights and sound as part of the decorations. But while The Spooky Porch is intended to scare, this is intended to be theatrical, and to amaze.
The code to the project can be found on Instructables.com, as can the schematics.
Most of the components are easy to find, off-the-shelf lighting equipment. It features four flood lights, each illuminating in succession; one strobe light; some speakers; and a passive infrared sensor. These can be found on eBay for as little as $4, as well as on maker emporium Element14.
The Screaming Ghost
Scare Factor: 11/10
Complexity: Easy
Are you a curmudgeon? Do you hate trick or treaters? Do you resent having to get up every five minutes to dole out free candy, when you could be watching Netflix in your bathrobe?
If so, this project is for you.
The Screaming Ghost promises to petrify anyone who dares knock on your door. It uses a motion detector to sense when someone is nearby. As they approach, it projects an ethereal ghost onto a pane of plexiglass, and emits a high-pitched shriek. Scary, eh?
It sounds complicated, but it's not. All you need is some plexiglass; some reflective paint; a projector; some speakers; and a motion detector. The code and design schematics are available toview on Instructables.com.
The Socrative Zombie
Scare Factor: 6/10
Complexity: Easy
Braaaains. Braaaains. Braaaains.
Everybody loves zombies. Zombies love brains. Especially this zombie, built by tecoed.co.uk.
The Socrative Zombie shoves speakers, an infra-red sensor, and a raspberry pi into a ghoulishly macabre papier-mâché zombie head. When a person approaches, the zombie starts chanting brains.
The code and schematics for The Socrative Zombie can be found here.
The Makey Makey Halloween Soundboard
Scare Factor: 7/10
Complexity: Medium
The Makey Makey is pretty rad. It allows you to turn everyday, conductive things (like fruit, pencil lead, and even your own body parts) into computer input devices. To get an idea of what I mean, check out this video by the inventor of the Makey Makey, Jay Silver:
But did you know that using a Raspberry Pi, some speakers, and a Makey Makey, you can create a haunting halloween soundboard? It's true. Check out this project from Mark Hanford.
Here, he uses a custom-built wooden case and the standard Makey Makey demo program to produce haunting sounds at the touch of a button.
Creepy Face Tracker
Scare Factor: 4/10
Complexity: Hard
Have you ever seen a painting where the eyes follow you? Creepy, isn't it? The Creepy Face Tracker, from Tony DiCola, does just that. Except here, it's not Uncle Sam that's following your every move, but rather a ghoulish skull.
On the face of it, this project is rather simple, and requires only a PC monitor, and the Raspberry Pi camera module 5 Things You Can Do with the Raspberry Pi Camera Module 5 Things You Can Do with the Raspberry Pi Camera Module One of the first expansions you should buy for the Raspberry Pi is the camera module. With a dedicated connector, the camera can be used for a variety of tasks. Let's take a look. Read More . However, unlike the other projects, it uses the comparatively complicated C++ graphics framework OpenFrameworks, and requires the user to compile the code. As a result, I'm labeling this as hard.
It's worth pointing out that this program renders the ghostly image in real time. The developer recommends that you use the Raspberry Pi B+ The Raspberry Pi B+ Is Here. What's Changed? The Raspberry Pi B+ Is Here. What's Changed? Read More at a minimum. That said, to be safe, you're far more likely to be better off with the Raspberry Pi 2 Another New Raspberry Pi... and it Supports Windows 10 Another New Raspberry Pi... and it Supports Windows 10 Read More , which is a vastly more capable machine 5 Things Only a Raspberry Pi 2 Can Do 5 Things Only a Raspberry Pi 2 Can Do The latest edition of the pint-sized computer is awesome. So awesome, in fact, that there's 5 things you can only do on a Raspberry Pi 2. Read More .
Will you be making a Raspberry Pi halloween project? I want to hear about it. Leave me a comment in the box below, and we'll chat.


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Lancome Hypnose Drama Mascara Reviews
- Other Mascaras:
- Average: 4.1
- High: 5.0
- Brand:
- Lancome
Read 6 Reviews
REVIEW SNAPSHOT®by PowerReviews
Reviewed by 6 customers
Comments about Lancome Hypnose Drama Mascara:
I'm trying this mascara out for the first time thanks to a gift with purchase mini tube that I received with my order. I don't exactly fuss over my lashes, and I don't need Drama for everyday use, but I was amazed by how much I really love this look. I never apply more than one coat of mascara unless I know my tube is running low on product. My lashes look seriously lush and incredible! The lashes are separated, I didn't struggle with any clumping, and I love the deep black color (called Excessive Black, and the only color available in this formula). I went gray early, and color is one of the reasons I use mascara - to hide those gray lashes. Curl is not a problem for me, nor is length, but I love it when it looks like I have more lashes than really exist.
I'm thinking that this brush has a lot to do with the great results. I've seen brushes that have a gentle u-curve, brushes that are straight, brushes that are wider in the center and taper down at each end. This brush has lots of bristles that sort of flare out in different directions, and the shape of the brush sort of meanders. I have no idea what the thinking behind this design was, but this brush separates my lashes and makes them appear to have multiplied.
This isn't a drugstore-priced brand (although drugstore prices have really been getting up there in the past year or so!) but I will consider this for a future purchase. The name is easy to remember, and it certainly lives up to its claims. Lancome's website describes it as such:
"Get instant lash drama in a single coat with this ultra volume-boosting mascara that'll take lashes from so-so to show-stopping. The full contact brush, with its S-shaped curve, grasps and loads lashes for a fanned out, full body fringe. Lanc?me's luxe Texturizing Complex features highly saturated waxes and intense black pigments for maximum lash volume. The triple coating system delivers a fluid and creamy application to quickly and easily build big, battable lashes that won't clump or flake."
- Affiliation:
- I received a sample
Comments about Lancome Hypnose Drama Mascara:
I can't say that I've tried tons of mascara to really say this mascara is the absolute best, however this mascara is very very awesome!
I've always used drugstore mascara since mascaras should only be kept for a few months, lower end drugstore brands are extensions of higher end brands, mascaras should not be overly expensive since it's just a wand and some black "ink." However, I've received the lancome hypnose mascara from sephora as a a free sample and Ive been a fan ever since! My lashes are not very long and full for that matter. Upon applying it, my lashes looked darker, thicker, and longer! simply amazing stuff! My friend even thought that I wore fake lashes since it looked so long.
This mascara seriously beats any other mascaras that I've tried. I would definitely pay the price for it's worth it. Definitely give it a try!
Comments about Lancome Hypnose Drama Mascara:
This is the third in the Hypnose series that I've tried, while the mascara goes on well and does not clump, I've found that its overly flaky within an hour. While it does flake, I still find it much better than most other mascaras in the price range, and significantly better than cheaper ones. I have tried the waterproof Hypnose and while it looks great, its practically impossible to remove!
I went back to this one and use it every day, the color is strong and stays on well throughout the day. I feel like it does not clump your eye lashes together and certainly makes them look long and dramatic. I would say this is best for people with longer lashes as it does not add much volume. The mascara is easily removed with any decent eye make up remover or even a general face make up remover, which is a nice bonus. The wand is a good size but I personally prefer the straight wand and think the little kink is unnecessary.
Basically: good mascara for a decent price.
Comments about Lancome Hypnose Drama Mascara:
Lancome's Hypnose mascara is one of my absolute favorite mascaras. I have tried so many and I am always comparing them to the Hynose mascara. It gives me nice dramatic volume and I love that I can apply multiple coats and it doesn't get all clumpy! Many times I have received comments that it looks like I have false lashes on. I have never had an issue with it running or flaking on me like i have experience with others I have tried. I never use waterproof mascara because it is so hard to remove. So I stick with regular formulas versus waterproof. I also love the size and shape of the mascara wand. The shape helps to curl my lashes upward and the thickness of the brush gives me even application. The mascara last a while as well without drying out and it is pretty easy to remove. I use an oily base type eye makeup remover since I tend to wear heavier/dramatic eye makeup. Overall I love this mascara. However, I do wish it was a bit less pricey. I hate having to spend that much on a mascara when I can get one for 1/2 the price at a drug store. But I have yet to find a mascara I like as much as Hypnose.
Comments about Lancome Hypnose Drama Mascara:
I have long, straight lashes and am always looking for something to make them outstanding. I've tried dozens of mascaras from department stores as well as drug stores. This is the only expensive mascara I haven't felt cheated by. It;s not perfection, but it is a good move in the right direction. It's bold, and it gives definition and a bit of curl.
Comments about Lancome Hypnose Drama Mascara:
I absolutely love this mascara! I already own all the other mascaras that Lancome makes but this one takes the cake! It's a deep color of black so it gives me intense color and when i go for the evening smoky eye, it compliments it so well. It is easy to apply and does what it says it does, gives me the volume of the original Hypnose, fans out my lashes and makes them look dramatic. The new curved brush design helps me to spread my lashes out and coat them the way I like. This mascara is even good for everyday use, without my liner it still gives me some depth and drama but not enough to scare anyone. Ha! What I also love about this mascara is the cost. It's the same price as all the other mascaras that Lancome offers! If you need a new mascara you should give this one a try. I promise you will love it! I can not leave my house without, no matter where I'm going. I just hope the mascaras continue to get better and better from this one forward.


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Flower Burst Skinny Jean
- Approx. 12 in. leg opening
- Approx. 28 in. inseam
- 78% cotton, 21% polyester, 1% spandex
- Machine wash
- Model wears size 3/4
- Imported
There's nothing average about this slinky skinny jean. Built with a vintage wash, it features raw cut cuffs and beautiful flower embroidery, highlighted by faux leather, at the back pockets. Low rise. Fitted through leg.


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|Gyushi family Founder
Chuda Gyushi was a craftsman and armorer of the Spider Clan's Chuda family who joined the Daigotsu family as Daigotsu Gyushi after the Chuda's defection. He was granted his own vassal family, and eventually it was elevated to full family, with the name Gyushi.
Gyushi Family Edit
When Empress Iweko I granted the Spider the status of a Great Clan and the Chuda betrayed their former clan, Gyushi forsook his former family and swore fealty to the Daigotsu. After he had forged the Ancestral Armor of the Spider Clan Gyushi was granted the right to found his own Family [1] by Daigotsu Kanpeki, a vassal family. He was given an armory and the promise that if he ever betrays his lords, his life would be forfeited. Thus the Spider Clan has come to possess a Juhin-Kenzoku, a quartermaster or forging family. [2]
Full Spider Family Edit
After the Chuda defection the Spider had recruited shugenja from the students of Asako Kinuye, who lived in the place known as Kinuye's Grove. In 1199 Daigotsu Kanpeki severed any new recruitment from that place after he realized one of these students was not a human being anymore. The Spider Clan Champion summoned Daigotsu Gyushi, requesting him to provide the Spider with its shugenja ranks. [3] The Gyushi family was elevated to a full family of the Spider Clan, taking the name Gyushi. He carefully selected its individual members and slowly increased pressure on them until they become as strong as steel. [1]
War in the Empire Edit
In 1200 Iweko Seiken became Iweko II and shortly after Daigotsu Kanpeki renounced his position as Spider Clan Champion and declared war on the Empire. Gyushi and his vassals escaped from Toshi Ranbo to take refuge at Kyuden Shizuka, where the Susumu Daimyo Susumu Kuroko had assembled her followers. Uncertain of the loyalty of the Susumu dwelling within Kyuden Shizuka, Kanpeki elected to burn all inside. The palace was set to fire by the Daigotsu escort, with its doors locked. Survivors were in the custody of the Daigotsu family. [4]
|Preceded by:
|Gyushi Daimyo
1178 - Present
|Succeeded by:
The sources relating to this article are in conflict with each other.
|''Book of Earth (p.36, sidebar) mentions that Chuda Gyushi swears fealty to the new Spider Champion, Daigotsu Kanpeki, when the Chuda leaves the Spider Clan in 1174. But Kanpeki was still a kid back then and the Spider Clan ruled by the Council of the Spider. Leadership was only passed on to Kanpeki when he came of age
- ↑ 1.0 1.1 The Daimyo Project, by C. Thomas Hand, Mari Murdock, and Maxime Lemaire
- ↑ Book of Earth, p. 36, sidebar
- ↑ Scenes from the Empire 40, by Shawn Carman
- ↑ Why He Wrote, by Robert Denton
|This Spider Clan related article is a stub. That means that it has been started, but is incomplete. You can help by adding to the information here.


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Jess and Nick may have driven to Mexico and back since season 3 began, but that doesn't mean all the great times that brought them together should be left in the rearview. As New Girl: The Complete Second Season comes out on DVD and Blu-ray today, EW can exclusively offer up an outtake from "Cooler" that shows the whole gang rockin' the game of True American that led to THAT KISS. Who knew the country's favorite rule-free drinking game had a theme song? Ringtone, please!
After that, just for funsies, check out the official "Full of Schmidt" reel of Max Greenfield's best moments as the loft's favorite former heavyweight. From this one-minute supercut alone, there have to be enough Douchebag Jar contributions to buy a lifetime supply of shower gelato. Watch below.
True American, now with 100 percent more music… and sexy Russians...
Schmidt happened!
New Girl: The Complete Second Season is out on DVD and Blu-ray today.


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Making a change can be scary, especially if that change is divorce. But unless you're in prison, you aren't really stuck. You just can't make a decision…or can you?
When so much information is at our fingertips, we tend to research things to the nth degree. Analysis paralysis takes over. What if I leave him and it doesn't work out? What if I fail? What if it isn't the right choice? Am I doing the right thing?
Don't OverThink It:Those questions can swirl around your head with the same effect of water swirling down a toilet. They have the potential to empty you, to drain you, to paralyze you with fear… in short, they are unproductive and add no benefit to your mental health and happiness.It's one thing to look at and weigh all your options after within a reasonable timeframe. It's another thing if you let those choices bog you down. And it's quite another if you let someone else control you and your choices.I listened when someone I loved told me I couldn't make it without him. He said I'd never be able to support myself, that no one would ever hire me because I'd been out of the workforce for too long. He told me I'd end up like his mother, dependent on others to help me out. He told me I was too old, too fat, too many kids and too ugly for anyone else to love me. He told me no one would ever love me like he did. (God, please I hope not. If so, I haven't done my due diligence.) He told me that when he was finished with me, I'd be homeless, penniless and I'd lose my children.With encouragement like that, I was paralyzed with fear and indecision. Even though I knew in my head that those things he said about me were bogus, my heart sometimes would fall into despair and need a reminder that the lies were not real…and not me.I've heard similar things from other women when trying to decide whether or not to divorce. I'm stuck, how can I support myself? Am I doing the right thing for my kids? Will they be mad at me? Will he turn them against me? Is this the best decision? What will people think if I stay? What will people think if I go?
Stop Being Paralyzed With Fear:In The Power of Love, Sue Johnson lays out the physical effects of love. "Sociologists are also finding that our life partner is often our only reliable source of support and comfort. Love's function is safety and survival." So what happens when that breaks down in a marriage and it's hard to figure out what the best option is? "Emotional disconnection literally hurts. Brain scans show that rejection by someone we depend on is processed in the same part of our brain, and in the same way, as physical pain."Well, I finally stopped being paralyzed with fear. I decided that while I could not control the situation or even control him, I could control how I react to the situation and at least control myself. I got back in shape physically and lost 10 lbs. I landed a full-time job and more than doubled my income from my flexible part-time job. From that moment in time, I stopped letting fear get in the way of making decisions. Even if the decisions may not always be perfect, they were my decisions and it was empowering.
Two Steps Forward, One Step Back:
If I thought it was a nightmare being in my marriage, it was nothing compared to what would come after I began to separate myself from my ex and everything that came after our divorce. In almost every instance I felt like it was a dance: two steps forward and one step back. Each chapter brought its own challenges and times when I felt stuck, scared and unsure. Fight or flight mode kicks in and makes decision-making nearly impossible.I've heard from others who feel stuck in unhappy marriages. I would never be so bold as to tell someone what decision they should make, but I will say that you shouldn't be scared to make one. Life is now. Why stay stuck in an unhappy situation?Some women were unhappy but decided to make their marriage work. Others decided it was better to leave. But the end result and the point is that they made a choice to make their situation better.
You Can't Please Everyone:
I've had a few friends who were afraid of what other people would think about their decision to divorce. People will judge. They will take the kernel of information they have and make a decision about your situation. But you can't live your life trying to please everyone. Because of what I've been through, I've heard from countless people who are going through all kinds of issues. You never know what someone is going through. Even those who judge you harshly are most likely dealing with their own issues. Some people will judge you for divorcing. Why didn't you try harder? But no one else has to live your life. That's your job. It's your job to be the best you that you can be and to make yourself happy. You can't spread joy if you don't feel it yourself. What comes out of you is what is within you. So if you want to spread joy, you must have it to begin with.I read somewhere that you should flip a coin because in that singular moment you're waiting for it to land, you typically figure out what is in your heart. I also seek advice from friends whose judgment I trust. With all of this information at our fingertips, we often forget to trust in our instincts and listen to our hearts.You have to trust that your decision making will lead to the best outcome, not necessarily the path itself. It is all within you if you choose to empower yourself.
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Everyone going through divorce deals with anger and stress. You have a choice, you can go through divorce or, grow through divorce.
Seeking divorce advice for men? Follow these tips from a divorced woman on how to go through the divorce process with less hassle and less stress.
If you're in a relationship that needs to end, but you're afraid of being alone, here's what you need to know. Never stay out of fear of being lonely!
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Divorce in ,general, is hard, but when divorcing a narcissist, there are things you need to watch out for financially when divorcing a narcissist.
Domestic violence takes on many forms. Shaming is a way abusers keep their victims silent and under control. This is my story of shaming by an abusive ex.
It's never easy to make the decision to divorce. Analyzing what it may mean for you and your children can cause mental paralysis and you can become stuck.


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Smisch Sweden
Smisch is a 34 year old singer/songwriter from Sweden. He has been writing music since he was nine years old and released his debut album "The Story Of My Life" 11th january 2017 containing personal pop songs with strong and clear melodies and storytelling lyrics. ... more
Streaming and Download help


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8 December 2015
Statement on Philippines Supreme Court decision
The Cornell Alliance for Science would like to express its disappointment in light of the decision on Bt talong (eggplant) by the Supreme Court of the Philippines on December 8, 2015.
According to the decision, the field-testing of Bt talong is "permanently enjoined," or prohibited. Additionally, the national biosafety system DA 2002-8 is declared "null and void," while any further field testing, import, or use of genetically modified organisms (GMO) is "temporarily enjoined" until a new biosafety order is passed.
In this decision, the Justices have sided with Greenpeace and others seeking a ban on the testing and development of Bt talong. The Court considered the submitted evidence without due consideration of scientific expertise, to the extent of granting validity to studies already shown unsound by the mainstream scientific community. Unfortunately, sources published by anti-biotechnology activists on the Internet were given more weight than peer-reviewed scientific articles published by world-renowned experts in top-ranked scholarly journals.
Following evidence submitted by Greenpeace and its witnesses at earlier hearings to the Court of Appeals, the Supreme Court ignored authoritative scientific governing bodies that attest to the absence of unique risks of GMOs. Such includes widely cited statements from organizations like the American Association for the Advancement of Science, the U.S. National Academies of Science, and other national academies around the world.
By blatantly privileging to the "no consensus" statements published by dissenting activist organizations, this court decision sets a bad precedent. The same reasoning could be applied in other areas such as climate science or vaccination research, where small numbers of dissenters challenge the overwhelming weight of expert opinion. It is disappointing that the Supreme Court gave equal merit to these witnesses despite their varying relevant scientific backgrounds and expertise on the subject — of Bt talong in particular, and GMOs in general. Should membership of a high caliber expert institution or a distinguished publication record in the peer-reviewed literature not carry more weight than a group that offers retracted articles or the misrepresentation of facts as evidence? This is an example of "false balance" of representation of science in action, and results in factually inaccurate statements going into the record, unchallenged.
As a partner institution involved in the development of Bt talong in the Philippines, as well as in India and Bangladesh (as part of the Agricultural Biotechnology Support Project II of USAID), the Alliance for Science at Cornell University rejects the assertions of witnesses supplied by anti-GMO groups. The Court states: "There exists a preponderance of evidence that the release of GMOs into the environment threatens to damage our ecosystems... and eventually the health of our people once the Bt eggplants are consumed as food."
This is not the case: Our university staff and faculty would not engage in a project with knowledge of even a small real risk of serious harm to the environment or human health. Bt crops have been widely consumed in the global food supply for nearly two decades, and hundreds of studies have confirmed that the Bt proteins are not toxic to animals other than target pest species. The same Bt protein is widely used as a pesticide spray by organic farmers.
In ruling against Bt talong, the Supreme Court uses the precautionary principle ill advisedly. It states that "uncertainty, the possibility of irreversible harm and the possibility of serious harm" posed by Bt talong field trials warrant invocation of the precautionary principle; that "cases must be resolved in favor of the constitutional right to a balanced and healthful ecology." Such a ruling neglects the already existing risk to farmers, consumers, and the environment of a cropping system that is dependent on the use of high inputs of potentially toxic insecticides.
In uncritically accepting the negative overall framing of the GMO issue presented by Greenpeace and other activist groups, the Court leaves little room for a genuinely balanced consideration of risks and benefits. This hinders scientific progress, and interrupts the knowledge-based improvements in agricultural sustainability in the Philippines. It denies the choice of farmers interested in cultivating Bt talong as a cost-effective, safer pest management method.
Stopping science and technological progress does not automatically reduce risk; instead, it raises different risks by not addressing pressing food security and environmental problems these emerging technologies are designed to address.
The Cornell Alliance for Science will continue to promote an informed conversation about plant biotechnology with the express goal of allowing farmers and consumers worldwide access to innovation needed to create a more sustainable agricultural system. The recent Philippine Supreme Court decision is a step backwards in this effort. It is a blow to the entire global scientific and agricultural communities, and a sad day for science.
23 November 2015
Cornell Alliance for Science Launches
Global Conversation to End Hunger
The Cornell Alliance for Science converged on the United Nations Nov. 17 to launch a global conversation on ending world hunger.
As the Manhattan skyline twinkled in the background, the Alliance's 25 newly graduated Global Leadership Fellows mingled with diplomats, journalists, academics and science allies, sharing the personal stories that prompted them to embrace technological tools in the quest for food security.
The Fellows, who represent 10 nations, had just completed a 12-week intensive course in science, communications and grassroots organizing at Cornell University. They were the first cohorts in a pioneering program conceived by Cornell plant biologist Dr. Sarah Evanega and funded by the Bill & Melinda Gates Foundation.
"We must use the tools of science to end the disparity we see around the world," Evanega told the crowd of 100 persons assembled at the gala. "I'd like to work toward ensuring that every parent has the opportunity to put warm nutritious food in front of their children three times a day, and that every mother can both feed her children and send them to school."
Representatives from the Ghana, Indonesia, Uganda and Kenya embassies spoke of the critical need to address world hunger issues and the role that biotechnology can play in advancing agriculture.
"I feel there couldn't be a better place than the UN to begin a conversation, but be careful of the UN — sometimes we talk too much and forget implementation in the field," said Indonesian Ambassador Desra Percaya. "It's very important."
The Fellows, who return to their countries this week, will pursue that implementation through campaigns and communication strategies aimed at improving public understanding of the role that biotechnology and science can play in ending hunger.
"Access to agricultural innovations can reduce drudgery, increase productivity and incomes, and ultimately increase opportunities for education," Evanega said.
"You must get to the villages where people are so you can help them make a difference, because that is where the problem is," Kenyan goodwill ambassador Peter Rono advised the Fellows.
"I have no doubt their efforts will be of great consequence," said Dr. Max Pfeffer, Senior Associate Dean of Cornell University's College of Agriculture and Life Science.
Among those sharing their personal stories were Father Emmanuel C. Alparce of the Philippines, who said that millions of his countrymen are hungry. "I'm here because I believe biotech will improve the lives of my people and my farmers," he said.
Joni Kamiya told of how her father's Hawaii papaya farm was suffering "a slow death" from the ravages of a plant virus until Cornell scientists genetically engineered a virus-resistant variety.
"He accepted this technology to keep our farm going," she said, noting that now she devotes much of her time to dispelling misinformation about biotechnology on social media. "It's funny that my little thing on the Internet was helping farmers in Hawaii, and hopefully it will help others around the world."
Nassib Mugwanya spoke of how farmers in his home country of Uganda are suffering from hunger and economic setbacks because plant viruses are ravaging the essential cassava crop. Scientists have genetically engineered cassava to resist these viruses, but political activists have blocked its introduction.
"Even though the solution is right in front of us, right within our reach, the legislative climate has not been right for...farmers to have this crop on their farms," he said.
Jayson Merkley, an Oregon-based researcher with Vegan GMO, told of how he'd initially been opposed to biotechnology, but had come to understand that the anti-GMO stance held by most vegans is hindering efforts to address hunger and poverty.
"Despite being good people with the best of intentions, we're driving a wedge between these biotech tools and the people who need them," Merkley said.
For more information visit http://allianceforscience.cornell.edu/leadershiptraining.
10 June 2015
Cornell Alliance for Science launches Global Ag Journalism Fellowship
Seoul, South Korea: The Cornell Alliance for Science is launching a global fellowship program to support journalism in agriculture. The program was announced during a session jointly sponsored by the Alliance for Science and SciDev.Net that explores the role of journalists in promoting technology choice for farmers at the 9th Conference of the World Federation of Science Journalists in Seoul, South Korea on June 10, 2015.
"We want to support independent journalists who are doing in-depth reporting on important topics in agriculture related to food security and innovative agricultural practices," said Sarah Evanega, director of the Alliance for Science. "We want to hear about scientists who are engaged with end users in developing new technologies, the men and women farmers who are adopting them, novel approaches to communicating about the technologies, and — at the end of the day — what the impact is for families and communities."
According to Evanega, there will be two kinds of fellowships: opportunities that support journalists working solo, and opportunities that support collaborations involving two or more journalists. For the latter option, the Alliance encourages applications from journalists where half of the team comes from the developing world, and the other half from more developed countries.
"It's great to see the Alliance recognize the particular value and needs of journalists from the industrializing world. I am also happy to see the provision for some innovative collaboration between journalists," said Nick Ishmael Perkins, director of SciDev.Net, the world's leading online source of news and analysis about science and technology across the developing world.
Individual Journalism Fellowship awards will be issued in amounts from $5000 to $15,000. Collaborative Journalism Fellowship awards will be issued in amounts up to $25,000. The Alliance hopes that the Collaborative track will inspire working partnerships among journalists who may otherwise not have the opportunity to work together.
"Supporting journalists to write articles that explore access to innovation is core to the Alliance's mission," said Evanega.
The Alliance for Science is a communications initiative with the goal of promoting access to scientific innovation as a means of enhancing food security, improving environmental sustainability and raising the quality of life globally. Based at Cornell University and funded by a grant from the Bill & Melinda Gates Foundation, the Alliance is evolving chapters with partners around the globe.
Applications will be reviewed beginning July 1, 2015 and will operate on a rolling basis. To apply, see: http://allianceforscience.cornell.edu/SJFellowship
1 April 2015
US Government Seeks Young Scientists for $25,000 ASPIRE Prize
The United States Department of State is seeking nominations to represent the United States for the 2015 APEC Science Prize for Innovation, Research and Education (ASPIRE). Sponsored by Wiley and Elsevier, the $25,000 ASPIRE Prize award recognizes young scientists who have demonstrated a commitment to both excellence in scientific research, cooperation with scientists from other Asian Pacific Economic Cooperation (APEC) countries. The deadline for nominees is April 20th. For more information on how to apply, please click here.
30 March 2015
Brazilian Scientists Thank the Alliance and our Allies
Recently over 1400 people showed their support to researchers in Brazil whose crops had been destroyed, and encouraged the Brazilian government to continue important meetings on the potential use of biotechnology. Click here to learn more. The scientists at Futuregene, whose research was vandalized, asked the Alliance to send the signers their thank you message:
"We would like to express our gratitude for the petition of support by the international scientific community condemning the invasion of FuturaGene's facilities in Brazil and the disruption of the Brazilian Technical Commission of Biosafety (CTNBio) meeting of March the 5th, which was due to deliberate and vote on the submission by FuturaGene for the commercial deployment of a yield enhanced genetically modified eucalyptus event.
These violent acts came as a shocking surprise both for FuturaGene and the CTNBio. They are in stark contrast to the open and transparent dialogue which FuturaGene has maintained with civil society throughout its development process and against the legal and democratic principles under which the CTNBio is constituted, as well as the basic need and right to conduct objective scientific discovery and development for the betterment of society.
The significant support that the initiative has assembled from scientists and society in general is of great importance to FuturaGene, since it encourages us to persevere in our mission towards building a more sustainable future through technological innovation. We believe it will also be highly appreciated by the CTNBio members, as this is a clear demonstration of sympathy and support from their scientific peers from around the world.
Warm regards,
The FuturaGene Team"
21 August 2014
New Cornell Alliance for Science awarded grant
The Cornell Alliance for Science seeks to add a stronger voice for science and depolarize the charged debate around agricultural biotechnology and genetically modified organisms (GMOs). Supported by a $5.6 million grant from the Bill & Melinda Gates Foundation, the Cornell Alliance for Science will help inform decision-makers and consumers through an online information portal and training programs to help researchers and stakeholders effectively communicate the potential impacts of agricultural technology and how such technology works.
The project will involve developing multimedia resources, including videos of farmers from around the world documenting their struggles to deal with pests, diseases, crop failure and the limited resources available in the face of poverty and climate change.
"Proponents and opponents alike speculate whether biotech crops are of benefit to farmers, but rarely are those farmers engaged in the biotech discourse or their voices heard," said Sarah Evanega, senior associate director of International Programs in Cornell's College of Agriculture and Life Sciences (CALS), who will lead the project.
"Our goal is to depolarize the GMO debate and engage with potential partners who may share common values around poverty reduction and sustainable agriculture, but may not be well informed about the potential biotechnology has for solving major agricultural challenges," Evanega said. "For instance, pro-biotech activists share a lot of the same anti-pesticide, low-input, sustainable-agriculture vision as the organic movement."
Evanega and her team hope to help engage such potential partners and foster more constructive policies about biotechnology as a useful tool to address major agricultural challenges.
The grant will allow the Cornell Alliance for Science to host annual conferences, short courses and semesterlong CALS certificate programs in biotechnology leadership, among other activities.
Evanega said the initial concept was informed by a February 2014 gathering at Cornell of 34 representatives from public sector and not-for-profit organizations in 12 countries that discussed a new vision for biotechnology communications.
"Like elsewhere in the world, African scientists still find it challenging to effectively inform the public about their work and its relevance to society," said Barbara M. Zawedde, coordinator of the Uganda Biosciences Information Center at the National Agricultural Research Organization. "Our effective communication will enable African farmers and citizens to exercise their sovereign right of informed decisions on whether to adopt certain crops and technologies depending on their needs and priorities."
In part because of its land-grant heritage, CALS regularly hosts forums and media events about various agricultural technologies and the role they could play in providing sustainable solutions to major global challenges.
"Biotechnology is a potential game-changer for farmers in less developed countries and an important tool in the toolbox for addressing global challenges, such as persistent poverty, a changing and erratic climate, and the challenge of feeding 9 billion people by 2050," said Kathryn J. Boor, the Ronald P. Lynch Dean of CALS. "Improving agricultural biotechnology communications is a challenge that must be met if innovations developed in public sector institutions like Cornell are ever to reach farmers in their fields."


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|Grant Ingersoll <gsing...@apache.org>
|Re: Latest version of spatial contrib
|Fri, 19 Mar 2010 18:59:30 GMT
On Mar 19, 2010, at 12:04 PM, Chris Male wrote: > Hi Alex, > > Its a direction that is still under heavy development but its definitely the direction I would like it go. I think once the code merge happens, I can easily bring in the updates I made too. For instance, I've added a fair number of distance utilities beyond just haversine that people should find useful. I'd like to see the distance stuff more pluggable -Grant --------------------------------------------------------------------- To unsubscribe, e-mail: firstname.lastname@example.com For additional commands, e-mail: email@example.com
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Henry V (Henry Charles Ferdinand Mary, French: Henri Charles Ferdinand Marie) was King of France. Before that, he was styled comte de Chambord and duc de Bordeaux.
He was born on 29 September 1820 in the Tuleries Palace, Paris, a son of Prince Charles Ferdinand of France (who died before Henry's birth) and his wife Princess Carolina of Naples and Sicily. He became King of France upon the death of his paternal uncle, Louis XIX, on 3 June 1844. He died on 24 August 1883 in the Palace of Versaille, Paris.
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On May 2 those of us who reside within the Orrville City School District will have the opportunity to vote for the renewal the Orrville Public Library's operating levy. I am reaching out to all registered voters in the school district and asking you to vote YES on renewal.
The .75 mill renewal levy does not account for any new taxes. It does provide 14 percent of the Orrville Public Library budget. For a homeowner with a $100,000 home it will cost just $17.20 per year, which is much less than other media usage rates such as cable or internet company subscriptions.
The Orrville Public Library is an amazing community resource. Our library has received national recognition for being a top U.S. library and has been a key economic driver by providing contemporary high interest materials, supplying information for lifelong learning and offering a gateway to outside resources. In addition the library succeeds by stimulating young children's interest in reading and learning and by partnering with our school system to supplement the educational needs of school-age children.
Here are a few interesting facts about the value that our library provides to our community every year:
The library is open 56 hours a week.
The Clevnet App and E-book programs are open 24/7/365.
The facility is 25,000 square feet.
The library has over 70,000 items.
There are nearly 12,000 registered borrowers.
Total circulation is over 500,000.
2,400 people visit the library every week.
Almost 1,400 items are delivered to homebound and elderly patrons.
Lastly I would like to recognize Daphne Silchuk-Ashcraft, director of the Orrville Public Library and her amazing team. Daphne holds a master's degree in library and information science with a specialization in young adult literature. Daphne and her team have worked very hard to use resources wisely to engage our community at all ages especially our youth, inspiring in them the drive to read, to learn and to develop expertise in the use of technology. The excellent team at the Orrville Public Library is always welcoming, courteous and extremely helpful.
Please vote on May 2 to support the passage of the Orrville Public Library renewal levy.
Dr. Marchelle Suppan, CEO
Aultman Orrville Hospital


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5 Indian-Made Games You Should Play Today
- Editorials, Gaming, India
- January 26, 2016
I went in for Phobia expecting something better than the sad excuses for psychological horror that Bollywood generally churns out, was almost disappointed, until I absolutely wasn't. Spoilers ahead. While a twist ending is to be expected in any thriller, the twist ending in Phobia came in like a storm transforming what seemed like any oldREAD MORE
This is a special article by Souvik Mukherjee, who researches videogames and storytelling and has a PhD on the subject. When he's not saving the Capital Wasteland, he teaches English at Presidency University, Kolkata. Sixteen years ago, when I was a rather diffident English Literature back bencher in Jadavpur University in Calcutta, India, a friend ofREAD MORE
This article was a collaborative effort between multiple ASidCast members who attended the EDGE X event. I.e. Sayak and Trilokesh. As gaming industry is picking up pace in India, many colleges and other educational institutions have embraced PC gaming and its related technology, which was quite evident from the gaming events in the Annual TechnologicalREAD MORE
India is a country with the majority of it's population young, and so having a large number of potential gamers, around 23 million, as estimated by leading Global GPU manufacturing company, Nvidia. But the current rate is much lower, counting at about 10 to 12 million gamers at present, who play games more than 2READ MORE
First of all, a little announcement from Roach Interactive. Bird of Light, our upcoming game, will be released for PC on Steam soon, through a US-based PC game publisher. Now that's done and over with, some of you will have noticed us promoting the game for mobile for the last few months; it turns outREAD MORE
Video gaming, in general, set up camp in the urban pockets of India long after it had made its humongous impact all around the globe. However, displaying the scantest signs of decelerating of their passage in making their way into being a staple among Indian teens and children alike, today the video gaming industry inREAD MORE


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|Contributors wanted
By SaintsAdmin
|Friday 16 Aug 2013 09:22:00
Browse all Latest Headlines articles
|As we are on the cusp of a new season, I'm going to try and fire this site up again. Due to work comittments, I cannot work on it full time but will contribute when I can. Therefore any help that can be provided with moderation or article writing etc would be much appreciated. Of course if you are happy with its current state and wish to continue to use other sites such as TUI aswell then that's OK. This site was once pretty active and it would be great to get it as active as the Blue Few's down the road. Cheers Wessex


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Sell your city
What about the city you live in would you tell people is the reason why they should move there? If you were doing a promotional advertisement on where you live what would you include?
My city? The cost of living is not terrible. The crime rate is low , the people are friendly and it's very rural which I like. The schools are great too and there's shopping but no huge malls or Walmarts in this city.
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No ocean in Noblesville Indiana, I know that it is still a beauty....
You had me at beaches, lol. I would love to live near one! COL is so high here in the beach area though, I simply couldn't afford it.
My city is 2 hours away from the mountains, 2 hours away from the ocean, and about 30 minutes away from the depths of the woods
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I would love to live in Seattle. Maybe one day I will transplant to that coast.
That kind of city with less criminals is the best it doesn't matter how big the shops are peace and security is most important .you don't have to live with fear.
I reside in Chicago. This big city has all of the attractions that a major city has, plenty of shopping, entertainment, restaurants and one of the most beautiful skylines that only China can rival, plenty of great schools if you are willing to dish out the dough, interesting politics and great beaches and fine homes! For those who like to walk on that wild side there are plenty of tight places as well, stay in shape by jogging on the lakefront or try out one of the many marathons, there are plenty of things to do for families as well great museums and zoos and wonderful parades, despite the weather we have some of the most beautiful 4 seasons around I love Chicago pricey but nicey :)
This is college town, "Tracktown USA" where the Ducks have put Oregon on the maps. Small town feel, great for raising families. It's about education, sports, grass roots and advocacy; not a fashion show. Far enough away from the big city and the rat race. A half hour drive from the camp sites and other outdoor activities. You can't beat their $1.50 movie theatres!
I wouldn't suggest moving to where I live. I live in Saginaw, Michigan, there is a lot of crime here, the streets are bad and have potholes all over the place, it's an old run down city for the most part and nothing has really happened here in years. It use to be an automotive town like Detroit and Flint but not as big as either one and now there is a lot of medical around here, the auto industry has lost about 60% of it's workforce, lots of abandoned properties and high crime in many areas. We're just on the outside of town and where we live isn't too bad but it's not great either.
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I am a single mom of two fantastic kiddos that I love to pieces. Currently in school working towards my teaching degree. You can find me most days on www.mommathoughts.com when I am not here chit chatting! :)


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