text:
What is JotForm?
JotForm is a free online form builder which helps you create online forms without writing a single line of code. No sign-up required.
At JotForm, we want to make sure that you're getting the online form builder help that you need. Our friendly customer support team is available 24/7.
We believe that if one user has a question, there could be more users who may have the same question. This is why many of our support forum threads are public and available to be searched and viewed. If you'd like help immediately, feel free to search for a similar question, or submit your question or concern.
How does the storage work?Asked by ttepedino on October 10, 2016 at 11:16 AM
Hi support people,
I see that the free account comes with 1000 MB of storage. How is that allocated? Does that have to do with content that I upload to my forms? Or, does that have to do with information that is uploaded through the form? Meaning, if I allow for PDF and MP4 uploads that are linked via Google Drive integration, what impact does that have on the 1000 MB of storage?
Thank you so much!
Tony Tepedino
JotForm Support
Hi Tony,
File storage limit only refers to the files that are stored in your JotForm account. So, if you integrate your form with other file storage systems you will have a greater flexibility at storage.
Please contact us again if you need any further assistance.


text:
|Message view
|« Date » · « Thread »
|« Date » · « Thread »
|"Concetto Elvio Bonafede (JIRA)" <j...@apache.org>
|[jira] [Resolved] (STANBOL-122) Delete install.sh files and lib and ext directories from kres
|Mon, 28 Mar 2011 14:30:05 GMT
[ https://issues.apache.org/jira/browse/STANBOL-122?page=com.atlassian.jira.plugin.system.issuetabpanels:all-tabpanel ] Concetto Elvio Bonafede resolved STANBOL-122. --------------------------------------------- Resolution: Fixed The directories lib and ext are not necessary any more. Now the owlapi, owl-link and hermit artifcat are installed normally, so lib and ext can be deleted. The same for the two sh files (install and heavyinstall), they are not necessary. > Delete install.sh files and lib and ext directories from kres > ------------------------------------------------------------- > > Key: STANBOL-122 > URL: https://issues.apache.org/jira/browse/STANBOL-122 > Project: Stanbol > Issue Type: Task > Components: KReS > Reporter: Concetto Elvio Bonafede > Assignee: Concetto Elvio Bonafede > Priority: Minor > > With issue STANBOL-27 fixed is not necessary any more to install dependencies manually, therefore the files *.sh and directories lib and ext can be deleted from kres. -- This message is automatically generated by JIRA. For more information on JIRA, see: http://www.atlassian.com/software/jira
|View raw message

subset: commoncrawl


text:
Shrimp and Pasta
Pasta and shrimp make a great match in these recipes that combine all types of flavorful ingredients to go from rich and creamy to savory and spicy. Try them all and let your family pick a new pasta and shrimp favorite.
Lemony Shrimp LinguineFamily Circle
Packed with pasta, shrimp and vegetables, this easy recipe is a complete meal.
Shrimp MarinaraFamily Circle
Make your own marinara in minutes by combining tomatoes, sugar, oregano and red pepper flakes, then use it to top this shrimp pasta, stuff inside lasagna or layer on spaghetti and meatballs.
Mediterranean ShrimpFamily Circle
Packed with shrimp, artichoke hearts and kalamata olives, this 20-minute pasta recipe showcases the delicious ingredients used in Mediterranean cooking.
Gingered Shrimp with SobaFamily Circle
Donatellas Cavatelli with Spicy ShrimpBetter Homes and Gardens
If only we could all have an Italian grandmother who would teach us to prepare fresh pasta. This is the next best thing. Peppery arugula and shrimp are tossed in a red pepper oil, before joining the cavatelli in a symphony of flavor. Add some breadsticks and dinner is served.
Fettuccine with Fennel, Shrimp, and PeasBetter Homes and Gardens
Shrimp and vegetables in a light wine sauce make up this low-calorie pasta dinner.
Apricot Shrimp with Fruity CouscousFamily Circle
Stir apricots, cranberries, and hazelnuts into couscous to make a pilaf-style accompaniment for the spicy-sweet apricot-glazed shrimp.
Fettuccine with Baby Artichokes and ShrimpBetter Homes and Gardens
When fresh baby artichokes are not available, use frozen artichoke hearts for this vegetable, pasta, and shrimp main dish recipe.
Shrimp ScampiFamily Circle
Be sure to serve this garlic-laden dish with lots of bread so everyone can sop up all of the delicious sauce.
Scallop and Shrimp FettuccineFamily Circle
Couscous 'N' Garlic ShrimpBetter Homes and Gardens
Sauteed shrimp served over couscous and spinach makes for a complete meal.
Peanut-Sauced Shrimp and PastaBetter Homes and Gardens
Delicious shrimp, savory peanut sauce, and crispy asparagus are combined with rice noodles in this easy to make recipe that'll be ready in under 30 minutes.
Scallops and Shrimp with LinguineBetter Homes and Gardens
Not one but two shellfish favorites make this simple pasta dish a surefire winner.
Linguine with Garlic ShrimpBetter Homes and Gardens
Roasting garlic, as for this shrimp dish, results in a mellow, buttery paste. Also use roasted garlic to spread on Italian bread or stir into mashed potatoes.
Linguini with Shrimp and Pine NutsMidwest Living
Dry sherry flavors the broth, and the crushed red pepper adds a tiny bite to this seafood and pasta dinner entree.


text:
Choose Between Two Options
- $29 for one month of unlimited yoga classes ($150 value)
- $39 for 10 yoga classes ($120 value)
- See the schedule
Yoga at The Raven
Outside Yoga at The Raven, wicker chairs nestle beneath a rustic wooden pergola, giving students a place to perch before and after class. This peaceful setting—with its yellow walls, lanterns, and vines—eschews modern minimalism in favor of natural beauty. And it certainly helps the studio's instructors cultivate tranquility as they teach everything from flowing hatha movements to Acro Yoga. While students learn proper form and deepen their practice, the temple-like ambiance grants respite for their hearts, which often grow weary from pumping emotions throughout the body.


text:
1550 Platte St, STE D, Denver +1 (303) 284 6222
Hours & Location+1 (303) 284 6222
Your cart is empty, why not check out some of our newest items?
is back-ordered. We will ship it separately in 10 to 15 days.
Saturdays Surf signature swim short; functional with a clean look, featuring their Process Print- inspired by glaze brush techniques in ceramics.
by Norse Projects


text:
Carlos Zambrano is weary of discussing his surprising conversion from ace of the Chicago Cubs' starting rotation to late-inning reliever. Moving a pitcher making nearly $18 million this season into a setup role has been the talk of Chicago for more than two weeks, and Zambrano is talked out.
"There is nothing left to say," Zambrano said. "I'm in the bullpen. It's where my team needs me, and I'll do the best job I can until they trade for somebody to take my place and I go back to starting." However, Zambrano was willing to give a simple explanation of how he approaches his new job. "I know I'm only going to be in the game for an inning or two, so I just let it go and try to get everybody out," he said Tuesday night after the Cubs lost 3-2 to the Pirates.
Zambrano has made just three relief appearances thus far, but the stats show his approach out of the 'pen has been drastically different.
According to Pitch f/x, Zambrano is throwing his four-seam fastball 57.9 percent of the time as a reliever as opposed to just 16.5 percent of the time in his four starts this season.
Further breaking down Zambrano's pitch selection as a reliever, he has thrown 17.1 percent sinkers, 11.8 percent changeups, 7.9 percent cut fastballs and 5.3 percent sliders. As a starter, Zambrano was more concerned about pitching to contact, as he threw 33.3 percent sinkers and 26.6 percent changeups with 16.5 percent four-seamers, 15.0 percent sliders, 5.5 percent cut fastballs and 3.0 percent split-finger fastballs. After relying heavily on his off-speed stuff as a starter, he has basically shelved his breaking pitches out of the bullpen. Considering he doesn't have to worry about pacing himself, Zambrano is also throwing a tick harder, as a reliever as his four-seamer is averaging 91.7 mph, compared to 90.7 mph as a starter.
Zambrano has allowed one run in four innings in his three relief appearances after going 1-2 with a 7.45 ERA as a starter. More notable is that the Cubs are 8-5 since moving him into the bullpen after starting the season 5-9. Furthermore, the Cubs have won all three games in which Zambrano has appeared as a reliever.
"It's seemed to have given our entire team more confidence since we put Z in the eighth-inning role," Cubs manager Lou Piniella said. "We feel like we're going to win the games we should win now, and that means a lot. Just check our record. You don't make a move like this lightly. You do it because you think it gives you the best chance to win games, and it's working out very well for us."
John Perrotto is editor-in-chief of Baseball Prospectus.


text:
A brave police officer, late Sergeant Bapi Sen of Calcutta Police, laid down his life in the line of duty to save a citizen of this city.
We appeal to the unknown lady and her companion to come forward to help us (in) establishing the case against the accused persons
Commissioner of Police,
That was the Calcutta Police appeal to the two Calcuttans who could help investigators sew up the Bapi Sen murder case issued on Tuesday. The tenor of the letter, signed by the citys top cop, whose five constables had battered the sergeant on the last night of 2002, clearly meant that the police have failed to trace the yet unknown woman on a motorcycle whom Bapi had stepped forward to save.
Calcutta Police had, on Saturday, engaged an artist to sketch the woman and her male companion, behind whom she was riding pillion. On Sunday, more than two dozen copies of the rough profile, sketched on the basis of divergent versions fed by the various witnesses, were sent out from Bowbazar to police stations across the city.
The fact that not a single police station has, so far, had any success, forced police commissioner Sujoy Chakraborty to issue Tuesdays appeal to the city at large. Their (the woman and her companion) cooperation will be the true tribute to the fallen hero, the appeal added, before assuring them that their identities would not be disclosed.
The last beneficiaries of Sens final act of heroism have been urged to contact Chakraborty directly, or the deputy commissioners in charge of the detective department (Soumen Mitra) and the central division (Zulfiquar Hasan).
The day after Bapi Sen lost the last battle of life, state transport minister Subhas Chakraborty, speaking at a programme in Behrampore, admitted that the incident proved how indisciplined the force had become. With officials in Calcutta alleging that a section of the lower cadre of the reserved force was trying to shield its colleagues, Chakraborty said the incident had occurred only because of a steady deterioration in the police force and an erosion of values.
Even as Chakraborty took a swipe at the failings of the force, the city police chief shifted the Bapi Sen case to the detective department, following reported complaints from Bowbazar police station against a section of the reserved force.
Reserved force constables are on duty at the central lock-up at Lalbazar (where the five arrested policemen are being kept) and the courts (where they are being produced), and so Chakraborty was advised to effect the shift.


text:
Need to get blood tests in Cinco Ranch, TX? Simply order online and get blood tests done at a lab in Cinco Ranch, TX (Find More Locations):
How much does it cost to Get Blood Test?
Our prices to Get Blood Test include the doctor's order that you need to get tested in Cinco Ranch, TX, all lab fees and taxes, and a pdf copy of your results. To get started, CLICK HERE.
What does a test report look like if I Get Blood Test through you?
For a sample report of one of our panels you can get, please CLICK HERE.
In a time of rising healthcare costs, we are delighted to help patients Get Blood Test in Cinco Ranch, TX.
Get Blood Test in other cities near Cinco Ranch, TX:Brookshire | Cypress | Fulshear | Greatwood | Houston | Katy | Orchard | Pattison | Richmond | Rosenberg | Simonton | Stafford | Sugar Land | Wallis


text:
>> Tarantino was born in Knoxville, Tennessee, the son of Tony Tarantino, an actor and amateur musician, and Connie McHugh, a nurse.
>> He has been quoted as saying, 'When people ask me if I went to film school I tell them, 'no, I went to films.'
>> Production of Kill Bill: Vol 1 was delayed because of Uma Thurman's pregnancy.
>> He was the head judge at the 2004 Cannes Film Festival, where 'Pulp Fiction' won the Palme D'or, the top honour, only ten years earlier.
>> He was originally offered the chance to direct Speed, but turned it down.


text:
ete, Violet, Sam and Addison adjust to their new, singles lives in different ways. Addison questions how much she wants a baby and confides in Jake, Violet considers an offer to go on a date with a young, hot paramedic, and Sam and Pete have a bachelors' night at a local bar. Meanwhile, Charlotte faces a personal, ethical dilemma when Amelia uncovers a secret about Mason's mom, Erica, and Sheldon refuses to bend to the pressure when an old friend from the police force wants him to rubber stamp a fellow cop suffering from PTSD.Resumen IMDb.com
|Nombre del documento
|Private Practice S05E11.srt


text:
13 total
Allergies: Patients are often given drugs to which they are allergic. Wrong Dosages: Patients may be given the right drugs in the wrong dosages Common Drugs: Some common drugs such as blood thinners
Cerebral Palsy Cerebral palsy includes a variety of disabling brain disorders. It may be associated with prematurity, genetic disorders, infections during pregnancy, lack of oxygen to the brain durin
Anesthesia Anesthesis or sedation, even when given for "minor" procedures, requires careful attention to drug dosages and control of respirations. While improved monitoring devices have greatly reduc


text:
We'll help you find the right solution for your needs
Does this sound like your topic?
Let us know when your receive great advice so we can thank our lawyers and point others with similar questions in the right direction.Got it!
I have brought up the criminal aspect to local authority. After getting a "field report" I was mortified as this (which I have more evidence) was either a bomb or someone making it look as if there was a bomb on my vehicle. To be blunt, I don't know if it was small town police or...something. I have made many excuses and need to get closure. Most importantly, I don't want this to happen to someone else. I believe this to be a hate crime in which I have the evidence to pursue further investigation.
Even if you haven't been charged with anything (yet), it is always a good idea to have your attorney present when being questioned by the police (especially if you have reason to believe that criminal charges are likely to be brought against you).
Ms. Berjis is licensed to practice law in the State of California. The laws of your jurisdiction may differ and thus this answer is for informational and educational purposes only and is not to be considered as legal advice. Since all facts are not addressed in the question, this answer could change depending on other significant and important facts. This answer in no way constitutes an attorney-client relationship.Ask a similar question
Confusing post.
You have evidence of a crime you want to turn over,having already reported something--but you're afraid you will be charged if you do, is that right? Recommend you meet with a criminal defense attorney before you do anything else.
NOT LEGAL ADVICE. FOR EDUCATION AND INFORMATION ONLY. Mr. Rafter is licensed to practice in the Commonwealth of Virginia and the US Federal Courts in Virginia. There is no implied or actual attorney-client relationship arising from this education exchange. You should speak with an attorney licensed in your state, to whom you have provided all the facts before you take steps that may impact your legal rights. Mr. Rafter is under no obligation to answer subsequent emails or phone calls related to this matter.Ask a similar question
I suggest you talk to a lawyer if you have more evidence you like to disclosure, but afraid you could be charged if you do so. It's always better to talk to a lawyer and let her/him assist you in the preliminary stages rather than gave statement to law enforcement which may incriminate you. If you have more questions you can call or email me. Good luck.
Post a free question on our public forum.Ask a Question
- or -
Search for lawyers by reviews and ratings.Find a Lawyer


text:
On Thu, Dec 17, 1998 at 09:02:52PM -0800, Oscar Levi wrote: > On Thu, Dec 17, 1998 at 11:07:29PM -0500, Joey Hess wrote: > > Oscar Levi wrote: > > > Not necessarily true. A crash bug that affects 1 out of 10000 runs of > > > a program is not release critical. > > > > That is correct. > > > > > A security hole, in of itself, is not a release critical bug. > > > > That is incorrect. > > > > You seem to be confusing a bug that crashes the kernel and a security hole > > that may crash the kernel, or allow access to private info, or anything > > else. A security hole can be reproduced at will by an attacker, without a > > great deal of difficulty. > > Is it correct that this security hole requires login access to the > computer? If an attack can be perpetrated from anywhere on the > internet to an internet connected computer, then it is clear that the > hole in 2.0.35 has a high probability of exploitation since a large > percentage GNU/Linux systems are Internet connected. If the attack > requires access to a user account on the machine, then the exploit is > overrated. It is all in the interpretation of 'great deal of Did you forget to take your medication today? That's a ridiculous statement, obviously an exploit that requires an account is not as serious as one that doesn't but it is still a big concern. You shouldn't have to worry about whether users want to exploit your system or not, it shouldn't be possible in the first place. > difficulty.' > > > > We don't have guidelines for release that we can use to decide if this > > > is important or not. > > > > Yes we do. We have a release manager who says we will not ship if we have > > critical bugs. We have a definition[1] of critical bugs that says "critical > > makes unrelated software on the system (or the whole system) break, or > > causes serious data loss, or introduces a >>>security hole<<< on systems > > where you install the package." > > While the opinion of a release manager is the inevitable last stand > for determining when to release, it is not a substitute for parameters > that we ALL can measure. Nor for a testing framework. > > > > In your opinion, is it worth a three-week delay > > > to switch kernels? > > > > Yes. It's worth a delay to fix any security hole. Debian must not ship with > > known security holes. Quality is our priority, we have never sacrificed > > quality for marketing concerns. > > Let's let the security issue pass. It isn't important. I agree we > should upgrade. Now, at this point is it worth shipping slink? By > the time we get around to gel'ing it, the packages will be out of > date. Some already are. Umm, call me crazy but 2.0.36 isn't much different than 2.0.35, just replace it and let's be on our merry way. It's not like we are switching from libc5 to libc6 or something. And I'm pretty sure security is an imporant issue with most people. > Software release is time-critical. No matter how hard you beat the > quality drum, the distribution that can ship often will show the best. > RedHat has shipped several buggy distributions in the 5.x series. I > just tried to install 5.2 and found a nest of problems. Unpleasant as > it is, users can only choose a distribution that ships. Hamm is out > of the running and the competition is fierce. They shiped with bugs > that requires 30MB of updates. But they shipped...and people use it. Are you suggesting we ship a buggy distribution? I agree timely releases are imporant but sacrificing security for a release date is not a good idea. -- Stephen Crowley email@example.com, firstname.lastname@example.com -* Finger firstname.lastname@example.com for my public key. PGP#22714B25 *-
Description: PGP signature


text:
Question: Carefully explain the distinction between stratified random sampling and cluster
Carefully explain the distinction between stratified random sampling and cluster sampling. Provide illustrations of sampling problems where each of these techniques might be useful.
View Solution:
View Solution:
Answer to relevant QuestionsThe supervisor of a plant obtained a random sample of employee experience (in months) and times to complete a task (in minutes). Graph the data with a component bar chart. Construct a time-series plot for the following number of customers shopping at a new mall during a given week. Day Number of Customers Monday .......... 525 Tuesday .......... 540 Wednesday ........ 469 Thursday ...The U.S. Senate has 100 members. Information was obtained from the individuals responsible for managing correspondence in 61 senators' offices. Of these, 38 specified a minimum number of letters that must be received on an ...Refer to the data of Exercise 17.27. If 80 managers were sampled, determine how many sample members would be from subdivision 1 under each of the following schemes. a. Proportional allocation b. Optimum allocation, assuming ...Of the 1,395 colleges in the United States, 364 have 2-year schools. In a random sample of 40 two-year schools, it was found that the text Statistics Can Be Fun was used in 10 of the schools. In an independent random sample ...
Post your question


text:
Pepha Tight Lifting treatment
Pepha Tight Lifting treatment (for mature skin, which lost its complexion)
The Pepha Tight product family is the ideal care for extremely dry and sensitive skin, which is exposed to stress. The products provide beneficial hydration and an effective protection for the skin. Because of the alga active agents the products have a firming and strengthening effect on the connective tissue of the skin.
Course of the treatment:
- Cleansing - Pre Care Oxygen face milk
- Treatment with tonic - Pre Care Oxygen lotion
- Peeling - Pre Care face peeling
- Treatment with tonic - Pre Care Oxygen lotion
- Ampoules (+ ultrasound) - Superior Harmony ampoules
- Wrinkle-filling up, lifting mask - Pepha Tight Treatment set
- Relaxing massage - Pepha Tight lifting cream
Duration of treatment: 60 minutes


text:
- Toyz N Da Hood (feat. Bootsy Collins)
- Sweat (feat. David Guetta Remix)
- The Way Life Used To Be
- My Own Way (feat. Mr. Porter)
- Wonder What I Do (feat. Uncle Chucc)
- My Fucn House (feat. Young Jeezy And E-40)
- Peer Pressure (feat. Traci Nelson)
- I Don't Need No Bitch (feat. Devin The Dude And Kobe Honeycutt)
- Platinum (feat. R. Kelly)
- Boom (feat. T-Pain)
- We Rest In Cali (feat. Goldie Loc And Bootsy Collins)
- El Lay (feat. Marty James)
- Gangbang Rookie (feat. Pilot)
- The Weed Iz Mine (feat. Wiz Khalifa)
- Wet (Sweat)
- Take U Home (feat. Too Short, Daz And Kokane)
- Sumthin Like This Night (feat. Gorillaz)
- Superman (feat. Willie Nelson)
- Eyez Closed (feat. Kanye West And John Legend)
- Raised In Da Hood
- It's D Only Thang
- Cold Game (feat. Latoiya Williams)
- Rádio interpreta
- Rok vydání: 2011
- Žánry: Dance, Electronic, Fitko, Hip hop, Pánská jízda, Rap, Rated R
- Vydavatelství: EMI
- Text písničky
[Intro: Snoop Dogg]Aiyyo Battlecat! (What's that?)It's your dawg, Big Snoopy D-O-double-GAy cuz, I was thinkin (what's that?)We need to take it back, to the way it used to beYou feel me? (Well c'mon~!)Yeah, uhh (what?) C'monYeah, drift with meDrift with me c'mon, drift with me y'all{"Reflections of, the way life used to be"}Ye-yeah, uhh{"And it's alright..."}[Snoop Dogg]Take it back to the afros, and the naturalsCape cutter picks we slips into the back rowsO.G. my nigga, for real doeStraight up off the Eastside, top of the hill yoI'm lookin at the overviewThinkin 'bout eighty-six, damn I was overdueWalkin in the hood, makin mixtapes tryin to walk up out the hoodWhile I'm chuckin at the hood, nigga talk about the hoodthat I came from it raised me, that's real Crip crazyWadoo, oops-a-daisy!Demon or a heathen, schemin while I'm dreaminScreamin to get even, seein is believinAnd don't you forget thatGet it to you get back, hit that, kick backThree flies one-a-wayReminisce about the thangs that my grandmomma use to sayStay in your own lane, stay on your ownand quit tryin to be grownDay turned to night, and play turned to fight{"It's alright"} Yeah, I guess my granny was right[Chorus: Snoop] + {samples}{"Reflections of, the way life used to be"}Drift with me... {"It's alright"} drift with me[Snoop Dogg]I like them girls from Ladera Heights, or the girls on HillsI take a trip up to World On Wheelsand get in a fight, make it back to my ridePop shots at some suckers disrespectin the 'sideMy big homey, my cuzzo, schoolyard bozoSlid me away, just to get me awayI'm just a Long Beach nigga outside of my hoodI'm bangin, ridin, but doin it goodAnd when I get locked down there ain't hidin and wonderinAs soon as I hit the County, I'm up in 4800With the dealers, the killers, the realest, the beastsThe best from the West and the beast from the EastYeah, I'm actin a foolI'm gettin my degree, from gladiator schoolI chose this life cause I knows this lifeSell a little crack and my flows is tightI'm clear on my choice and what's cold isI can still hear my grandma's voiceShe say day turned to night and play turned to fight{"It's alright"} Yeah, I guess my granny was right[Chorus: Snoop] + {samples}{"Reflections of, the way life used to be"}Reminisce with me... {"It's alright"}[Snoop Dogg]If you get caught then you don't walk cause you don't talkAnd these was the rules, squeeze on these foolsI came up in a different era homeyWhere the G's is the G's and the little wannabe's really want itWanna be like, cause the C-lifemake you wanna G like, now who you wanna be like?(Snoop~!) That fool on the TV screenOr the homey on the corner gettin major cream?In the Cadillac, beatin like BattlecatA nigga with money, don't know how to actSmoke 'til your eyes get cataractsAll money nonsense, yeah none of that, quarter sack, run it backQuarterback, rock him up, bag him up, front him thatIf the trick, jump the track, do you want your money back?Lil' bitch was a bunny rat; watch for the funny actCause it's gon' come... and my granny said it's no funShe say day turned to night, and play turned to fight{"It's alright"} Yeah, I guess my granny was right[Outro: samples]{"Reflections of, the way life used to be"}{"It's alright"}
- The Way Life Used To Be (03:43)


text:
- Description
You can have an attractive and contemporary appearance for your living room with this console table. The piece consists of 8mm tempered glass sides and weathered grey surfaces. The matching lower shelf is great for keeping books, magazines, plants and framed photos. If you are looking sleek, clean and slightly rustic look for your living room, this sofa table is bound to please.Includes
1 Sofa TableDimensions
Sofa Table, 49"L x 16"D x 34"H
- Additional Information
Additional Information
SKU 12602610 GTIN N/A Collection N/A Assemble Length 49 Assemble Width 16 Assemble Height 34 Assembly Required Yes Material N/A Finish Black Styles Contemporary Shapes N/A Shipping Time 1-2 Weeks Free Shipping Yes
- Reviews
Disclaimer: Pictures displayed may include optional products not included in the price. Computer monitors often display color variations. Color swatches are shown if alternative colors are available. Please call us or email us if you have any questions!


text:
Submit News
Quick Note: NASA's Remaining Space Shuttles Stripped, Prepared for Final Resting Places
Brandon Hill
March 29, 2012 2:45 PM
Recipient E-mail
Sender E-mail
America's mighty space fleet is sent into retirement
As a self-described space nut, it's with great sadness that I look upon these images of the remaining members of the Space Shuttle fleet being picked apart and readied for their new homes in museums.
The Atlantic
has posted 35 breathtaking pictures of Discovery, Atlantis, and Endeavour.
Discovery will find a new home in the Smithsonian's National Air and Space Museum while Endeavour will make its way to the California Space Center. Atlantis will be sent to the Kennedy Space Center.
The first orbital mission of the Space Shuttle fleet kicked off with Columbia on April 12, 1981. Space Shuttle Atlantis
made its final flight into space
on July 8, 2011 and
landed safely on July 21, 2011
. In total, there were 135 missions and two tragic accidents (first with Challenger in 1986 resulting in the loss of its crew, and later with the Columbia and its crew in 2003).
For now, you can
hop on over to
The Atlantic
to see the best that America had to offer in the modern era of space travel:
Shuttle Endeavour (L) and Shutte Discovery (R) [Source: The Atlantic]
For those that still wish to reach beyond Earth's orbit, we can still look forward to NASA's
Space Launch System
(SLS) which will eventually take astronauts to Mars.
The Atlantic
"Intel is investing heavily (think gazillions of dollars and bazillions of engineering man hours) in resources to create an Intel host controllers spec in order to speed time to market of the USB 3.0 technology." -- Intel blogger Nick Knupffer
Related Articles
NASA Unveils Design, Cost for Next Generation Space Launch System
September 14, 2011, 5:45 PM
Space Shuttle Atlantis Arrives Home Safely, Marks End of 30-Year Space Shuttle Program
July 21, 2011, 9:21 AM
Atlantis Blasts Off for NASA's Final Space Shuttle Mission
July 8, 2011, 11:29 AM
Latest Headlines
PIQ ROBOTTM reveals its new artificial intelligence software
November 29, 2016, 12:59 AM
One more time - Happy Thanksgiving to Everyone Around the World
November 24, 2016, 4:00 AM
Google's Smart Contact Lens Project gets halted for 2016
November 20, 2016, 7:00 AM
Cell Research Study shows African Americans have greater immune response to infection
November 10, 2016, 1:00 AM
UTHealth Clinical Trial Shows Progress Using Stem Cells to Treat Traumatic Brain Injury
November 8, 2016, 1:00 AM
Uber Partners with Circulation to Pilot Program Connecting Transportation and Digital Health Care
November 6, 2016, 5:00 AM
More Headlines
Most Popular Articles
Samsung 2017 QLED TV – Guaranteed no Burn-In Display
August 18, 2017, 6:55 AM
Two great updates from Google
August 20, 2017, 6:42 AM
Best Buy Student Discount on the HP Spectre x360
August 17, 2017, 6:00 AM
Shonin – Palm-sized cam that attaches to the body to record videos and store them to the cloud.
August 17, 2017, 6:00 AM
Asus Zenfone 4 Pro – Craftsmanship and Technical Brilliance in the palm of your hand.
August 16, 2017, 6:53 AM
Latest Blog Posts
Samsung has a Smart Speaker in the Works
Nenfort Golit
Aug 24, 2017, 6:00 AM
Own a Sony Xperia? – Not as waterproof as they say.
Elroy Bethell
Aug 23, 2017, 6:56 AM
Do you want to know who's driving in your neighborhood?
DailyTech Staff
Aug 22, 2017, 6:04 AM
US Navy ship collides with oil tanker off Singapore
DailyTech Staff
Aug 21, 2017, 6:25 AM
Japan launches satellite for better GPS system
DailyTech Staff
Aug 20, 2017, 6:52 AM
Apple Watch 3 gone to final testing Phase:
DailyTech Staff
Aug 19, 2017, 6:24 AM
Can Didi out-network Uber to win the global ridesharing market?
DailyTech Staff
Aug 18, 2017, 6:23 AM
HBO social media hacked in latest cyber security breach
DailyTech Staff
Aug 17, 2017, 6:49 AM
Android O – Arrives in August 21, 2017
Elroy Bethell
Aug 17, 2017, 6:43 AM
Smart Biochip that helps to repair injuries and restore health.
Elroy Bethell
Aug 16, 2017, 7:10 AM
Samsung Galaxy Note 8 - One of the Biggest Smartphones so far by Samsung
DailyTech Staff
Aug 15, 2017, 6:23 AM
Google Voice Typing Update
Nenfort Golit
Aug 15, 2017, 6:00 AM
Google looks at health issues with purchase of Senosis
Elroy Bethell
Aug 14, 2017, 7:06 AM
Alzheimer's patients make soon find relief by playing video games.
Elroy Bethell
Aug 13, 2017, 6:35 AM
New LG V30 arrives in two weeks.
Elroy Bethell
Aug 12, 2017, 6:57 AM
Ready for an even larger iPhone?
Elroy Bethell
Aug 11, 2017, 6:35 AM
Google fires engineer for violating company's code of conduct.
Elroy Bethell
Aug 10, 2017, 6:50 AM
T-Mobile new android smartphone.
Nenfort Golit
Aug 10, 2017, 6:00 AM
Want to take the Perfect Selfie? Try this Selfie App.
Elroy Bethell
Aug 9, 2017, 6:45 AM
New Fitbit Smartwatch coming this fall.
DailyTech Staff
Aug 8, 2017, 6:00 AM
More Blog Posts
Copyright 2017 DailyTech LLC. -
RSS Feed
About Us
Terms, Conditions & Privacy Information
Kristopher Kubicki


text: Nazis in wwII Many Jews died in WWII. There were 5,860,000 deaths. Women in World War II worked in harsh conditions. Women were meant to be wives. Women worked in factories, some worked herder than men. jewish deaths over 6 million people were killed. wich was over 2.5% of the population. most died in death camps or concentration camps. the largest camp was Auchwitz. World war 2 was one of the largest conflicts ever recorded in history with not a part of the world untouched. Hitler volunteered to serve in the German army. He survived 4 years in the army. He went blind because of a gas tank explosion.


text:
When we think of trees here in Canada, red maples, spruce, and pine are a few that come to mind. And while some of us still gaze up at trees in wonder, sadly, many of us take them for granted, passing them by without a glance. But the trees below aren't what many of us would describe as typical. Some of these trees are so unusual, you won't believe they're real.
View next gallery Stylish solutions for storing your firewood
X of Y


text:
Question: Given an example of one account with high inherent risk
Given an example of one account with high inherent risk and one with low inherent risk?
View Solution:
View Solution:
Answer to relevant QuestionsWhat is the purpose of a control framework?How can the risk model be expanded to incorporate limitations to the audit that arise from accounting and other business risks?What are some examples of external and internal business performance measures? How can these performance measures motivate management to misstate the financial statements? Why does the auditor consider management's controls of business processes? What kinds of knowledge does the auditor gather to understand internal control and assess the risk of material misstatement?
Post your question


text:
Stricken with grief over many occurrences in his life, artist Adam Morsai is known for creating grim pieces of artwork, which he keeps stocked in his studio, only to be seen by his eyes. Since he rarely sells any of his work, Adam struggles with severe financial issues as well as his dark, depressing outlook on life.
One night, when Adam is passed out on his drawing desk, his art is suddenly changed. Dark turns to light, sadness, to happiness, death, to life. But, when he awakens to find his comforting artwork turned into beautiful pieces which could make him millions, he isn't happy about it at all...
He looks at his canvases on the walls, all changed from their original, disturbing forms into brighter scenes, and notices that in every one, two child-like sprites appear, having fun in the surroundings of each piece of art.
"Them..." He mutters, taking up a brush, and infecting every painting with his symbol, called the Morsaius. At the last picture, of a tower in front of a red and blue sky, he paints himself as a powerful, royal-looking figure, on the top of the fortress, and an army of monsters below on the ground.
Suddenly, Adam's eyes roll back into his head, and he falls to the floor of his apartment.
He opens his eyes, and sees a vast field in front of him, a red and blue sky above, and the stones of the top of a tower below him.
Darkness is returning to the paintings on the wall.
Seeking to destroy the ones that ruined his work, Morsai finds them, a boy and a girl, and steals the girl away to his tower, beckoning the boy to rescue her, only to bring them both to their death.
However, the boy must deal with the armies of monsters ready to tear away the colorful worlds and bring back the disturbing creations of their master...
Final Battles
"Well done, boy..." Morsai says in his dark voice as Forte makes it to the Tower's Roof.
Melody looks hopefully towards her partner, bound to a post by purple coils of darkness.
"You've made it this far, across five of my paintings, turned into your visions...can you not stop me, here and now, with what you think of me?" Morsai rhetorically asks of Forte.
"No, you can't!" Morsai is angry now. "You don't get to mess with anything, or anyone, in the name of 'help', because I don't want to be helped!!" A bolt of dark energy emits out of Morsai's hand, and hits Forte, who collapses to the stone-cold floor.
The girl screams and Morsai laughs. "I know what you're doing...Forte. My shadows have seen all of what Melody has to offer...her thoughts...her memories...so, brother and sister, you are...trapped in the world of art by a dark force...but, so selfless you two are, using the situation you're in to try and help artists like me...it's a shame that the same darkness that has trapped you has taken over me as well!" Lightning crackles and thunder booms above the tower.
Forte still lays unmoving on the floor. "I can spare you the trouble of dying with your sister, Forte...I want my creations back. You can't work without her, so I'll nullify you by getting rid of her, and maybe you'll stay with me for a bit...I do owe you. Without you two I could've never found what I needed most...confidence."
At Morsai's evil, proposition, Forte finds the energy to save his sister return to him, and gets up heroically.
The dark force that trapped Forte and Melody in the worlds of paintings rendered the two unable to speak. But, Forte's newfound light energy breaks this cruel restraint.
"I'd...rather...die...with...her." Forte struggles to say, turning down Morsai's offer.
"If that's what you want!" Morsai gathers dark energy in his hands as he prepares for battle.
After Morsai Battle
"Urrgh!" Morsai clashes to the cold stone of the tower roof, wet from the pouring rain of the fierce storm.
Forte runs to Melody and frees her from her captivity. They hug each other as Morsai lays, seemingly unconscious.
Suddenly, they feel the tower shake as the ground quakes with a terrible force. The storm picks up even more, and the three are struck by lightning...
Forte and Melody open their eyes to what appears to be a sterling white, gleaming world of purity and light. They think they are dead, until they recall that this is the place where the Holy Goddess Akaye explained to them their role as Painting Sprites, restorers of good in art.
Thunder booms and suddenly the place goes dark. The Morsaius begins to take hold on pillars of the once untouched sanctuary. A new, unknown goddess meets the two sprites, and her fallen follower...
"I am Kura...demon goddess of darkness...!" Kura begins. "I have absorbed the soul of your great Akaye, and now, you must be eradicated before her lightness' worshippers succeed in bringing more Painting Sprites to life, and ruining my dark hold on disturbed ones such as Morsai...first, they make the dark art, then, they band together, then, the world grows darker, and I, stronger..."
Kura reaches her hand outward, pushing Forte and Melody aside as she holds Morsai. He slowly recovers and his appearance changes drastically, fueled by the inner powers of pure darkness.
Forte and Melody now face Kura's supercharged follower, Final Morsai.
After Final Morsai
"NOOOO!!!" Morsai yells as his body is tormented with Kura ripping energy out of him for his failure. Morsai explodes in a shower of strange symbols once Kura is finished.
"Sprites of Akaye can never defeat goddesses..." Kura proclaims, as her true power is returned.
After Kura
Forte and Melody defeat Kura and take away her dark look that is similar to Final Morsai, revealing her true form as a human-like goddess.
"You don't know anything about me..." Kura speaks in a female voice that sounds electronically altered, like it's being warped. "I am only the greatest creation of Morsai, to please his most inner desires...there is no ruling darkness, no big evil, no wrong to banish...there is no Akaye...and there is no you."
"You're wrong." Forte responds.
"I speak from the creator himself." Kura clarifies. "There is no truer word. We are all creations of Morsai."
"But..." Melody starts. "We were human once. Something made us into who we are now."
"I only know what I was given to know. If you were real I could not tell you how you got here. But, I believe you were given that fact by Morsai just like I am being given my thoughts."
The screen fades, as Forte and Melody face each other, and the possible truth.
Adam Morsai awakens from his floor. All that remains now is a single painting, of the top of Morsai Tower, with Forte, Melody, and Kura. Morsai stares at it, wondering what is happening now that he has lost his connection with that world.
But wait! Who woke him?!
Morsai whips around, and, to his surprise, a little girl, no older than 9, stands before him.
"Who are you? Why are you here?" He asks.
"Those are mine." She points to the two painting sprites in the Morsai Tower picture.
"I know." Morsai responds.
"Why were you telling them that they were yours?"
"To get rid of them. To get my paintings back."
"But your paintings were evil. That's why they came here."
"Look, kid..." Morsai kneels down to her level. "Art is art. Some people have gift to speak with the art, become one with it and interact with their own characters and creations. You, me, we can do this. But that doesn't mean you can change someone else's work with your gift. You may not be able to handle or understand darker-themed artwork, but that does not mean it is evil and should be made brighter. There is a place and a meaning for everything. I need my dark art. It helps me. By making worlds darker than life, I can appreciate real life more, no matter how bad it may get. Do you understand?"
The girl nods.
"So, please, can you take Forte and Melody out of my paintings?"
"But why did you attack them? Threaten them, like a villain?"
"I didn't know what to do. I thought the best way to bring my work back was to invoke that same darkness against the light, and that if I won, my paintings would return. I'm sorry for the trouble I caused your two amazing little characters, I really am. What do you call them?"
"They are Painting Sprites, do-gooders in the world of artwork."
"That's very imaginative. Keep working. Build your world. Discover new ways to make it even better. Just, try not to tamper with anyone else's world. They need it as much as you need yours."
The girl smiled, and Morsai smiled back. The girl ran to the Morsai Tower painting and touched Forte with her left hand, and Melody with her right. When she pulled her hands back, the two sprites were gone, and Morsai's creations began to flow back into the canvasses.
The girl turned away and ran out of Adam Morsai's apartment.
"Wait!" Morsai called. "What is your name?"
"Akaye!" The girl yelled back.
Morsai would never forget that day. He made sure of it.
"Journal number 643. I helped a young artist named Akaye open her mind to the creativity of the world after combating her characters that were intent on changing my dark work into lighter tales. This has inspired to create my next story. An interactive medium from the point of view of Forte, the girl's male "painting sprite" character. The player will experience both my worlds and the new worlds that Forte and Melody overwrote mine with. In honor of the focus on paintings and a paint-like art style, I shall title my newest work, Painterly."
The End.


text:
Definition Edit
Cable modem service is
|is delivered by cable television companies through the same coaxial cables that deliver sound and pictures to television sets.[1]
Overview Edit
Cable television companies first began providing broadband cable modem service in the late 1990s. This service, which is primarily available in residential areas, enables cable operators to deliver broadband service through the same coaxial cables that deliver pictures and sound to television sets. Although the speed of service varies with many factors, download speeds of up to 6 Mbps are typical. Some cable providers are offering even higher download speeds, up to 100 Mbps.
References Edit
- ↑ Telecommunications: Projects and Policies Related to Deploying Broadband in Unserved and Underserved Areas, at 4.


text:
First Tutors: Music helps you to find a music production tutor in Wrexham and across the UK. First Tutors: Music profiles Wrexham music production tutors and others offering popular instruments like piano, violin and guitar. Grade and diploma music production tuition are all catered for across Wrexham as well as music production lessons just for fun. Use our site to search for music production tutors near you and select which music production teachers best suit your needs.
First Tutors: Music is the only place to search for the most suitable music production tutor for you in Wrexham, whether you want music production tuition to learn a new instrument, develop a hobby or improve as a musician.
Our search will list music production tutors in Wrexham by their cost and distance from you. Offered instruments include piano, violin and guitar for graded music exams or just for fun.
If you are a Wrexham music production tutor wishing to offer your music production tutoring services in Wrexham or anywhere else across the UK, please register with First Tutors: Music to commence giving music production tuition or find out more about us here.
Towns: Wrexham


text:
- Description
The White Bedroom in a Box is an easy addition to any existing bedroom decor.
With its simple, clean design and bright white finish, the set will complement a range of decor colors and styles.
Complete with everything you need for a bedroom, the set includes a round top headboard, a spacious storage dresser, large mirror and coordinating nightstand.
The dresser provides ample storage space for all of your clothing, accessories and linens.
A coordinating nightstand features a single storage drawer and a large open storage area for books and decorative accents.
Perfect for a child's bedroom or guest room.
Some Assembly Required.
More from this collection: Youth
- Additional Information
Additional Information
SKU 16000561 MPN 929-189 GTIN UPC 081438247571 Brand Powell Collection Youth Assemble Length N/A Assemble Width N/A Assemble Height N/A Assembly Required Yes Material Solid Wood Finish White Sizes N/A Bed Styles N/A Shipping Time 1-2 Weeks Free Shipping Yes
- Reviews
Disclaimer: Pictures displayed may include optional products not included in the price. Computer monitors often display color variations. Color swatches are shown if alternative colors are available. Please call us or email us if you have any questions!


text:
I've been seeing this guy for a few months, he started acting less interested and is now just being flat out rude(ignoring me, not responding to text) so I send him this:
"I don't really know what's going on with you, all I know is I used to have fun hanging out with you and that's all I ever thought about it so I don't know how you've managed to mess up something so simple. Let me know if you decide to stop being an idiot because I'm not wasting anymore time on this."
I thought the problem might be him thinking things were getting too serious but I'm not sure. I sent it this afternoon and he hasn't responded. How do you think he feels about this text? Do you think he will come to his senses and say something in a few days or maybe if I ran into him out at a bar? In other words, what's the chance of me getting him back or the best way to get him back. I'll run into him a lot, we have the same friends.
Guys, how would you react to this text message? The more opinions the better
I've been seeing this guy for a few months, he started acting less interested and is now just being flat out rude(ignoring me, not responding to text) so I send him this:
Have an opinion?
What Guys Said 2
You are definitely not on the road to getting him back. Pushing him away seems more like it. Women can be so analytical about things people say or do but sometimes don't take the time themselves to THINK before saying something. "Think before you speak". An old virtue taught to us as children, clearly forgotten or obstructed by your resentment towards him.
Check this out:
You say HE was being "flat out" rude by ignoring you and not responding back to your texts.
Let me ask you this. What were YOU being when you called him an "idiot", and told him how he's managed to "mess everything up"?
Does HE need to come to his senses? I believe you need to start with yourself first. Because you aren't using your senses if what you think you are doing is getting him to come back to you. And further more, I would think HE lost his senses if he responded and wanted anything to do with someone to speaks to someone that way. I'm not saying your not entitled to feel frustrated, but also to use good sense. No one is eager to get in a relationship with someone who would send texts like that.
If you notice, you seem to be angry when things aren't going your way. You say I USED to have fun until he messed it all up. Just because YOU aren't having fun, doesn't mean he's messed anything up.
So to answer your question, it's not him who
has to come to any senses, it's YOU that has to. If you want to attempt to get him back anyway. Personally, I feel that everyone who replies to this question will tell you that they have MORE sense than to want to come back. But here's my advice: think before you speak or write. Don't find fault or blame anyone for what's going. Tell him how you FEEL. Not that you FEEL he's being stupid (that's name calling, no point is getting across saying this.) Ask him what HE is feeling as well. Don't assume. ASK him if he's afraid of getting to serious. With guys, it's all about directness, not to be confused with insults.
It's my opinion that he's already seen a side of you he doesn't want to be apart of. Why wait until later to regret it. Also to finish up here, is that for now and for future references, you need to look at yourself and change whatever it is you needs to change before eve thinking about anyone else changing or making sacrifices for you. I would like to think if you received that same text from some guy, it is highly unlikely you would be dying to text him back immediately or feel compelled to be with this person. For all you know he was busy. Saw a bunch of angry insecure texts and thought it's not worth dealing with. Your trying to be manipulative by trying to get him to see you are worth having, and I think the opposite is being projected.00|00|0
Okay, so I just texted him and told him I was sorry and asked if I could talk to him. Will this help at all?
I wouldn't particularly like this part:
"Let me know if you decide to stop being an idiot because I'm not wasting anymore time on this."00|00|0
but would it just p*ss him off and make him not care or would it make him feel like a moron for giving up a girl like me when he had it so easy... maybe make him try for me again when he runs into me at a party later this week? Should I have not texted him at all? After a while he got cocky and stopped trying to impress me I didn't want him to think he was the only one dissatisfied the ultimate goal is to get him back. I know he'll have trouble resisting me if he gives me a chance to try.
- Show AllShow Less
too late. I know he was trying to end things with me, I think he thought it was getting too serious but I thought saying I never thought of it as "serious" would make him feel stupid but he could have seen it as too much drama and not worth dealing with. could it have pissed him off enough to not care that he ended it for no reason? that's why I said I was sorry and asked if we could talk, he never replied.could he just be thinking about it? I will see him tomorrow at a party what do I do/say?
Honestly, I wouldn't say anything, if he says something first then he actually wants things to work out. Maybe send a text and just say, "Hey, if you want to continue to (hang out/see me) then you (talk/text) to me because I'm not going to keep talking to you and not get a response" If he doesn't say anything then he wants to break it off.
What Girls Said 0
Be the first girl to share an opinion
and earn 1 more Xper point!
Learn more
Select as Most Helpful Opinion?
You cannot undo this action. The opinion owner is going to be notified and earn 7 XPER points.


text:
"Vision is not enough. It must be combined with venture. It is not enough to stare up the steps, we must step up the stairs." Vaclav Havel
Starting with only $300. and a dream, Teresa Hairston has pushed past obstacles to find opportunities, and made her dream reality. Her experience and expertise includes the varied components of entrepreneur, leader and now, mentor.
Dr. Teresa Hairston is uniquely qualified to help others who have dreams and visions, due to her nearly 25 years of experience as founder/publisher of Gospel Today Magazine. Publishing is a tough business! Of the thousands of publications that launch annually, less than 5% make it for more than 5 years. Gospel Today Magazine began in 1989 and is still in business.
Teresa Hairston not only understands writing and publishing, she understands business. These days, no matter what your dream is, you need a strategy. Thomas Edison once stated, "Vision without execution is hallucination!" Whether you're raising a baby or a business, you need a strategy.
Industry-based strategies are a combination of specific factors that consider economic climate, available resources, talent, knowledge and positioning.
Book Dr Hairston Now:


text:
Product Features
An ultimately versatile baselayer, the Capilene 2 Lightweight Crew satisfies the toughest demands. With an outrageously fast dry-time, moisture wicking properties, and flexibility, this shirt can be a stand alone top, or underneath other layers in colder climates. Stay dry and comfortable no matter what in the Capilene 2 crew.
- 20-UPF sun protection
- 3.6-oz (122-g) Polartec® Power Dry® 100% polyester (solids: 59% recycled; heathers: 43% recycled) double knit, with Polygiene® permanent odor control
- Open knit promotes airflow, is inherently stretchy and provides excellent wicking for endurance activities in cool to moderate temperatures
- Patagonia's fastest-drying baselayer fabric insulates enough for use on chilly days and can be worn beneath other layers
- Rib-knit neckline is soft next to skin
- Raglan sleeves and offset shoulder seams merge out of the way of pack straps
- Side seams roll forward for comfort under layers
- Thumb loops for secure hand coverage
- Machine wash cold, tumble dry at low temperature
Product Specs
|Men's shirt style
|Men's sleeve length
|Long sleeve
|Quick Drying
|5.1 oz (145 g)
Customer Reviews 1 item(s)Add Your Review
- "Very good midlayer."
I've used this hoodie as a midlayer over a capaline 4 and under a an arcteryx shell, and this combo has served me well so far. It breaths well and does an excellent job of regulating my temperature. The fit and finish of this jacket is top notch. The hood works well under my helmet, which was already a snug fit. The only real functional con is that the zipper doesn't do the best job of staying zipped up to the top. This is obviously an expensive item, but I think it's a worth while investment, especially if you can find it on sale.
Yes, I would recommend this product.


text: It was announced this week that EXID has been invited to perform at ChinaJoy 2016, the country's largest gaming convention. They are the first K-pop girl group to perform at this annual event! The members were seen at Incheon International Airport on July 28 where they were catching a flight to Shanghai for the appearance. At this time, LE could be seen wearing a D Logo Zipper Jacket from DRINKSCANCODE ($173). This Korean brand has been a frequent sponsor of EXID during their "L.I.E." promotions.


text:
Most Helpful Guy
Feeling pretty because you ARE pretty.11|00|0
Most Helpful Girl
You're so beautiful! <300|00|0
Feeling pretty because you ARE pretty.
You're so beautiful! <3
Have an opinion?
Very cute, but sadly the pic is a bit over-exposed - much of the detail in the center of your face is washed out. Terrific smile, though. :)
Those eyes, BOOM!
You look so pretty in that pic
Well wowowaaweewaahh
Yo fam I think I'm getting sick... with jungle fever xD
You aiight. You got a pretty smile and some cute dimples.
Your smile could light up a room... beautiful
I wouldn't say no
I think same as you do
yes pretty nice
You are very pretty :)
You're looking pretty too! 😍
You're really pretty! you have a very nice smile. Have a good day!
Wow your eyes!!!
Those eyes... So jealous...
Seriously your like really pretty.
You are gorgeous!
Well, you ARE pretty :)
Your fucking eyes 😍😍😍 flawless
You have a great smile and pretty eyes
Wahh gorgeous girl!
Good for you


text:
It's no secret that messaging has exploded in the last few years. Slack, Spark, Whatsapp, iMessage, Snapchat, etc. When was the last time you actually used the phone app to talk to friends or family?Read More >
It's no secret that messaging has exploded in the last few years. Slack, Spark, Whatsapp, iMessage, Snapchat, etc. When was the last time you actually used the phone app to talk to friends or family?Read More >
Altocloud is proud to announce their latest feature: Twitter Direct Messaging. This is just the latest addition to our wide range of communication channels that allow our customers to interact with their customers. Now agents can make sales, handle queries and provide support to the Twitter community from Altocloud's Agent Desktop.Read More >
Inbound Sales, no it is not the latest industry buzzword. Thanks to Hubspot the term Inbound is now synonymous with how every company should be marketing and selling their products and services. Gone are the days of cold calls, email lists and door knocking. Your buyers are online, researching, comparing, and asking questions. It is up to you to join your audience online and help them through their customer journey. Companies who employ real time, contextual customer communication techniques are at a huge advantage with today's modern buyer.Read More >
See how Altocloud integrates with Tropo and Spark to create a Customer Engagement Solution. Altocloud opens Spark rooms for customer engagement.Read More >
"All others bring data."
W. Edwards Deming, the famous management consultant and statistician also said, "It is not enough to do your best; you must know what to do, and then do your best." Mr. Deming's advice was given at a time when decisions were not often made based upon data… as data was not so readily available. Today we have the opposite problem. As everyone is aware, the amount of data being created has exploded at an incredible rate. 90% of the data in the world today was created in the last two years.Read More >
Editors note: See Altocloud live at Magento Imagine Commerce 2015, April 20-22.
It's no secret to e-commerce companies that long-term business success lies in personalization of the overall customer experience. By targeting your recommendations and special offers to the individual needs and intent of each buyer, you increase the likelihood and size of both immediate and follow-on sales. Multichannel Merchant predicted that 2014 would be the year of personalization – although your organization may already be well down this path! Their "prediction" makes the point that personalization is a means to an end – relevant, timely experiences that increase sales – and that, most importantly: personalization depends on effective analytics that gives you real insights into likely customer behavior.Read More >
Editors note: See Altocloud live at Magento Imagine Commerce 2015, April 20-22.
For a business of any size, communication with your clients is obviously a critical part of creating strong customer relationships. We are all used to using our phones for all kinds of marketing, sales and support activity. But is the phone now obsolete for e-commerce businesses? When all of your customers are online, do you really want them to be hunting down phone numbers and getting lost in a completely disjointed experience that has no connection to their recent online activity?Read More >


text:
1 conference presentations on iOS and Test Driven Development.
See iOS conferences.
Your current filters are…
from Taking a Test Drive: Using TDD to Write an iOS App at iOSDev UK, 7th-9th September 2011
Added 5 years ago
Browse and track events by topic
Follow @lanyrd on Twitter.
Lanyrd on Facebook
· Blog
· Services
· Colophon
+ Cookies · Email us


text:
Corporation Bank has announced the final results for recruitment to the post of Assistant Managers. Candidates with a scorecard issued by IBPS PO/MT CWE were considered eligible.
A total of 290 candidates have been selected.
Click here for more details.
Click here for more bank recruitment news
Click here for upcoming bank exam news


text:
Fachbereich Chemie
- Englisch (46) (entfernen)
- cobalt (3)
- Clusterion (2)
- Infrarotspektroskopie (2)
- Microarray (2)
- Protonentransfer (2)
- deuteration (2)
- dipeptide (2)
- enamide (2)
- gas phase (2)
- Palladium-Catalyzed C–C Bond Formations via Activation of Carboxylic Acids and Their Derivatives (2013)
- Applications of carboxylic acids and their derivatives in transition metal-catalyzed cross-coupling reactions regio-selectively forming Csp3-Csp2, and Csp2-Csp2 bonds were explored in this thesis. Several important organic building blocks such as aryl acetates, diaryl acetates, imines, ketones, biaryls, styrenes and polysubstituted alkenes were successfully accessed from carboxylic acids and their derivatives by the means of C–H activation and decarboxylative cross-couplings. An efficient and practical protocol for the synthesis of biologically important ethyl 2-arylacates through the dealkoxycarbonlative cross-coupling reaction between aryl halides and malonates was developed. Activation of the alpha-proton of alkyl esters by a copper catalyst allowed the deprotonation of esters even in the presence of mild bases, leading to a straightforward and efficient approach to alkyl alpha-diarylacetate from simple alkyl acetates and aryl halides. The addition of a primary amine into the coupling reaction of alpha-oxocarboxylic acids and aryl halides led to an unprecedented low-temperature redox-neutral decarboxylative coupling process, providing a green and efficient method for the preparation of azomethines, in which all the three substituents can be independently varied. A minor modification of this protocol allowed us to easily access the corresponding ketones. The decarboxylative coupling of robust aryl mesylates as well as polysubstituted alkenyl mesylates using our customized imidazolyl phosphine ligands was realized, further expanding the scope of carbon electrophiles in decarboxylative coupling reactions. Variation of the ligands led to two complementary protocols, providing the corresponding biaryls and polysubstituted olefins in high yields. The use of a new class of pyrimidinyl phosphine ligands dramatically reduced the reaction temperatures of decarboxylative cross-coupling reactions between aromatic carboxylic acids and aryl or alkenyl triflates. The new catalyst system for the first time allowed the efficient decarboxylative biaryls synthesis at only 100 °C, representing a significant achievement in redox-neutral decarboxylative coupling reactions.
- New Linkers for Organic-Inorganic Hybrid Materials (2012)
- In this study, two outstanding subgroups of organic-inorganic hybrid materials have been investigated. The first part covers the design, synthesis, characterization and application of seven novel Metal Organic Frameworks (MOFs) containing functionalized biphenyl dicarboxylates as linkers. In the second part, the surface modification of the metal oxides ZrO2, TiO2 and Al2O3 using phosphonate derivates is reported. Firstly three functionalized MOF structures; ZnBrBPDC, ZnNO2BPDC and ZnNH2BPDC were synthesised using 4,4´-biphenyldicarboxylic acid derivatives with different functional groups (-Br, -NO2, -NH2) Powder X-ray diffraction (PXRD) measurements indicated that the synthesised MOFs posses the interpenetrated IRMOF-9 structure with a cubic topology, which was also confirmed with single crystal X-ray measurements. The chemical structure of the MOF materials was further proved by solid state NMR and IR measurements. N2 adsorption measurements showed Type I isotherms for all three structures with large surface areas. TGA measurements of the evacuated samples were in good agreement with the elemental analysis data. The results proved that their thermal stability is between 325 °C - 450 °C. Adsorption properties of these MOF structures were tested using light alkanes (CH4, C2H6, C3H8, and n-C4H10) at three different temperatures. For all adsorbents, the maximum uptakes were observed at 273 K. When the temperature was increased, the amount of the adsorbed gas decreased. All three MOFs showed strong affinities for n-butane. The lowest uptakes were observed for CH4. The effect of functional groups on the IRMOF series was also examined by synthesizing amide functionalized biphenyl linkers. For this purpose, four different linkers containing amides with different alkyl chains (C1-C4) were synthesized and used for the synthesis of four new MOF structures ZnAcBPDC, ZnPrBPDC, ZnBuBPDC and ZnPeBPDC. PXRD measurements of ZnAcBPDC indicated that the structure contains two different phases. PXRD patterns of ZnPrBPDC, ZnBuBPDC and ZnPeBPDC revealed non-interpenetrated structures which were further proved by single crystal X-ray measurements. The chemical structure of the MOF materials was further confirmed by X-ray spectoscopy, solid state NMR and IR measurements. N2 adsorption measurements of the MOF structures were carried out using different activation methods. For all four MOFs, Type I isotherms were obtained. ZnAcBPDC showed the highest BET surface area. ZnAcBPDC and ZnBuBPDC were tested for their alkane, alkene and CO2 adsorption capacities. In the second part of the work, the surface modification of three different metal oxides, ZrO2, TiO2 and Al2O3 was performed. For this purpose firstly three different fluorescent phosphonate derivatives containing thiophene units were synthesized from their halo derivatives in a four step synthesis and then used as coupling molecules for the surface modification. Nine different surfaces were obtained (38@TiO2, 39@TiO2, 40@TiO2, 38@Al2O3, 39@Al2O3, 40@Al2O3, 38@ZrO2, 39@ZrO2, 40@ZrO2). All three modified metal oxide surfaces were characterized using elemental analysis, solid state NMR and IR spectroscopy. The BET surface areas of the materials were determined by N2 adsorption measurements. TGA was used to determine the stability of the surfaces. Maximum loadings were obtained for ZrO2 surfaces. Due to the strong luminescence of the coupling molecules, the modified surfaces were checked for their light emission. All ZrO2 and Al2O3 surfaces showed fluorescence with exception of 40@Al2O3. On the other hand, for the modified TiO2 surfaces, no fluorescence could be observed.
- Pyrimidine Functionalized Phosphine Ligands and Their Application in Catalysis (2012)
- The scientific aim of this work was to synthesize and characterize new bidentate and tridentate phosphine ligands , their corresponding palladium complexes and to examine their application as homogenous catalysts. Later on, a part of the obtained palladium catalysts was immobilized and used as heterogonous catalyst. Pyrimidinyl functionalized diphenyl phosphine ligands were synthesized by ring closure of [2-(3-dimethylamino-1-oxoprop-2-en-yl)phenyl]diphenylphosphine with an excess of substituted guanidinium salts. Furthermore to increase the electron density at phosphorous centre the two aryl substituents on the phosphanyl group were exchanged against two alkyl substituents. Electron rich pyrimidinyl functionalized dialkyl phosphine ligands were synthesized from pyrimidinyl functionalized bromobenzene in a process involving lithiation followed by reaction with a chlorodialkylphosphine. Starting from the new synthesized diaryl phosphine ligands, their corresponding palladium complexes were synthesized. I was able to show that slight changes at the amino group of [(2-aminopyrimidin-4-yl)aryl]phosphines lead to pronounced differences in the stability and catalytic activity of the corresponding palladium(II) complexes. Having a P,C coordination mode, the palladium complex can catalyze rapidly the Suzuki coupling reaction of phenylbronic acid with arylbromides even at room temperature with a low loading. Using the NH2 group of the aminopyrimidine as a potential site for the introduction of an other substituent, bidentate and tridentate ligands containing phosphorous atoms connected to the aminopyrimidine group and their corresponding palladium complexes were synthesized and characterized. Two ligands [2- and 4-(4-(2-amino)pyrimidinyl)phenyl]diphenylphosphine (containing NH2 group) functionalized with a ethoxysilane group were synthesized. The palladium complexes based on these ligands were prepared and immobilized on commercial silica and MCM-41. Using elemental analysis, FT-IR, solid state 31P, 13C and 29Si CP–MAS NMR spectroscopy, XRD and N2 adsorption the success of the immobilization was confirmed and the structure of the heterogenized catalyst was investigated. The resulting heterogeneous catalysts were applied for the Suzuki reaction and exhibited excellent activity, selectivity and reusability.
- The ribosome-inactivating protein gelonin and parts thereof to be employed for a potential treatment of cancer (2012)
- Due to their N-glycosidase activity, ribosome-inactivating proteins (RIPs) are attractive candidates as antitumor and antiviral agents in medical and biological research. In the present study, we have successfully cloned two different truncated gelonins into pET-28a(+) vectors and expressed intact recombinant gelonin (rGel), recombinant C-terminally truncated gelonin (rC3-gelonin) and recombinant N- and C-terminally truncated gelonin (rN34C3-gelonin). Biological experiments showed that all these recombinant gelonins have no inhibiting effect on MCF-7 cell lines. These data suggest that the truncated-gelonins are still having a specific structure that does not allow for internalization into cells. Further, truncation of gelonin leads to partial or complete loss of N-glycosidase as well as DNase activity compared to intact rGel. Our data suggest that C-and N-terminal amino acid residues are involved in the catalytic and cytotoxic activities of rGel. In addition, the intact gelonin should be selected as a toxin in the immunoconjugate rather than truncated gelonin. In the second part, an immunotoxin composed of gelonin, a basic protein of 30 kDa isolated from the Indian plant Gelonium multiflorum and the cytotoxic drug MTX has been studied as a potential tool of gelonin delivery into the cytoplasm of cells. Results of many experiments showed that, on the average, about 5 molecules of MTX were coupled to one molecule of gelonin. The MTX-gelonin conjugate is able to reduce the viability of MCF-7 cell in a dose-dependent manner (ID50, 10 nM) as shown by MTT assay and significantly induce direct and oxidative DNA damage as shown by the alkaline comet assay. However, in-vitro translation toxicity MTX-gelonin conjugates have IC50, 50.5 ng/ml which is less toxic than that of gelonin alone IC50, 4.6 ng/ml. It can be concluded that the positive charge plays an important role in the N-glycosidase activity of gelonin. Furthermore, conjugation of MTX with gelonin through α- and γ- carboxyl groups leads to the partial loss of its anti-folate activity compared to free MTX. These results, taken together, indicate that conjugation of MTX to gelonin permits delivery of the gelonin into the cytoplasm of cancer cells and exerts a measurable toxic effect. In the third part, we have isolated and characterized two ribosome-inactivating proteins (RIPs) type I, gelonin and GAP31, from seeds of Gelonium multiflorum. Both proteins exhibit RNA-N-glycosidase activity. The amino acid sequences of gelonin and GAP31 were identified by MALDI and ESI mass spectrometry. Gelonin and GAP31 peptides - obtained by proteolytic digestion (trypsin and Arg-C) - are consistent with the amino acid sequence published by Rosenblum and Huang, respectively. Further structural characterization of gelonin and GAP31 (tryptic and Arg-C peptide mapping) showed that the two RIPs have 96% similarity in their sequence. Thus, these two proteins are most probably isoforms arisen from the same gene by alternative splicing. The ESI-MS analysis of gelonin and GAP31 exhibited at least three different post-translational modified forms. A standard plant paucidomannosidic N-glycosylation pattern (GlcNAc2Man2-5Xyl0-1 and GlcNAc2Man6-12Fuc1-2Xyl0-2) was identified using electrospray ionization MS for gelonin on N196 and GAP31 on N189, respectively. Based on these results, both proteins are located in the vacuoles of Gelonium multiflorum seeds.
- New N,N and N,N,N Ligands and Their Application in Catalytic Reactions (2012)
- The scientific intention of this work was to synthesize and characterize new bidentate, tridentate and multidentate ligands and to apply them in heterogenous catalysis. For each type of the ligands, new methods of synthesis were developed. Starting from 1,1'-(pyridine-2,6-diyl)diethanone and dimethylpyridine-2,6-dicarboxylate different bispyrazolpyridines were synthesized and novel ruthenium complexes of the type (L)(NNN)RuCl2 could be obtained. The complexes with L = triphenylphosphine turned out to be highly efficient catalyst precursors for the transfer hydrogenation of aromatic ketones. Introduction of a butyl group in the 5-positions of the pyrazoles leads to a pronounced increase of catalytic activity. To find a method for the synthesis of bispyrimidinepyridines, different reactants and condition were applied and it was found that these tridentate ligands can be obtained by mixing and grinding the tetraketone with guanidinium carbonate and silica, which plays the role of a catalyst in this ring closing reaction. The bidentate 2-amino-4-(2-pyridinyl)pyrimidines were synthesized from different substrates according to the desired substituent on the pyrimidine ring. Reacting these bidentate ligands with the ruthenium(II) precursor [(η6-cymene)Ru(Cl)(μ 2-Cl)]2 gave cationic ruthenium(II) complexes of the type [(η6-cymene)Ru(Cl)(adpm)]Cl (adpm = chelating 2-amino-4-(2-yridinyl)pyrimidine ligand). Stirring the freshly prepared complexes with either NaBPh4, NaBF4 or KPF6, the chloride anion was exchanged against other coordinating anions (BF4-, PF6-, BPh4-).Some of these ruthenium complexes have shown very special activities in the transfer hydrogenation of ketones by reacting them in the absence of the base. This led to detailed investigations on the mechanism of this reaction. According to the activities and with the help of ESI-MS experiments and DFT calculations, a mechanism was proposed for the transfer hydrogenation of acetophenone in the absence of the base. It shows that in the absence of the base, a C-H bond activation at the pyrimidine ring should occur to activate the catalyst. The palladium complexes of bidentate N,N ligands were examined in coupling reactions. As expected, they did not show very special activities. Multidentate ligands, having pyrimidine groups as relatively soft donors for late transition metals and simultaneously possessing a binding position for a hard Lewis-acid, could be obtained using the new synthesized bidentate and tridentate ligands.
- In vitro and in vivo biofunctional effects of selected coffee compounds, extracts and brews on key elements of adenosine receptor-mediated signaling pathways and on cellular heme oxygenase (2012)
- Mechanisms underlying the biological effects of coffee and its constituents are incompletely understood. Many effects have been attributed solely to caffeine, neglecting that coffee is a mixture of many chemical substances. Some authors suggest that the main mechanism of action of caffeine is to antagonize adenosine receptors (AR); a second effect is the inhibition of phosphodiesterases with the subsequent accumulation of cAMP and an intensification of the effects of catecholamines. Although the inhibition of phosphodiesterases may contribute to the actions of caffeine, there is growing evidence that most pharmacological effects of this xanthine result from antagonism of AR. One of the main objectives of this work was to investigate whether substances other than caffeine in coffee may influence the homeostasis of intracellular cyclic nucleotides in vitro and in vivo. The influence of selected coffee compounds, extracts and brews on key elements involved in the adenosine receptor-mediated signaling pathway have been investigated. A further aim of this work was also to determine if coffee or some coffee constituents may have a stimulatory effect on the cellular heme oxygenase activity (HO-activity). Two coffee extracts, a slightly (AB1) and an intensively roasted coffee (AB2), were studied along with selected individual compounds. Caffeine and low substituted pyrazines showed no effect on the HO-activity, while NMP, pyrazines with a greater substitution pattern such as Tetramethylpyrazine (TMP) and 2-Ethyl-3,5(6)-dimethylpyrazine (2-E-3,5-DMP) and both coffee extracts significantly induced the HO-activity in liver hepatocellular carcinoma (HepG2), intestinal colo-rectal adenocarcinoma (Caco-2) and in some instances in monocytic leukemia (MM6) cells. It was found that caffeine, theophylline, coffee extracts from conventional or functional coffees, pyrazines (2,3-DE-6-MP, 2-Isobutyl-3-methoxyP), 5-CQA and caffeic acid all significantly inhibited the basal cytoplasmatic PDE activity in lysates of lung tumour xenograft cells (LXFL529L) and human platelets. To a somewhat lesser extent, PDE inhibition was also found in experiments performed with paraxanthine and other pyrazines (2-E-3,5-DMP, TMP and 2-E-5-MP). Thus the degree of roasting has a considerable impact on constituents of influence for PDE activity. Caffeine, coffee polyphenols and some pyrazines and further, as yet unknown roasting products appear to represent the main modulating constituents. In two coffee intervention studies, a short-term (8 weeks) and a long-term study (24 weeks), comprising 8 and 84 healthy volunteers respectively, we examined extracellular key elements of the adenosine pathway including plasma adenosine levels and adenosine deaminase activity. Additionally, we studied the intracellular cAMP concentration and the PDE activity in platelets as surrogate biomarkers of adipocytes. Results of in vitro experiments had suggested that the concentrations of caffeine and coffee extracts required to obtain a half maximal inhibition were in the upper range of physiological conditions. Yet, it was demonstrated for the first time in vivo that moderate consumption of coffee can modulate the activity of platelet phosphodiesterases in humans in long and short term. In both studies, the first exposure to coffee showed a strong inhibition (p<0.001) of the PDE activity in the platelet lysates of the participants while the second coffee phase showed no or a slight effect when compared with the first coffee intervention. In both studies a significant increase (p<0.001) in intraplatelet cAMP concentrations during the wash-out phase (after the first coffee phase) was observed. This response could be due to inhibition of the PDE activity in the previously phase extending in to the wash out phase. However, the behavior of cAMP in the following study phases cannot be easily explained. It may be hypothesized that this effect is attributable to adaptive effects to allow PDE inhibition. One possibility is the modulation of the expression of membrane-bound adenosine receptors in platelet precursors, which still have a nucleus. This may potentially influence adenylate cyclase activity in mature platelets. For the observed effects, in addition to caffeine other ingredients of coffee appear to play a role. The findings suggest that monitoring of cAMP homeostasis in platelets is not a useful surrogate biomarker for effects in other tissues. Neither the activity of adenosine deaminase nor the adenosine concentrations in plasma were markedly modulated by the coffee consumption in both trials. This may reflect the fact that adenosine is subject to quick and effective enzymatic turnover by phosphorylation (adenosine kinase) or deamination (adenosine deaminase) allowing keep its concentration within a well balanced homeostasis. However, it is also well known, that considerable variability exists in the responses to coffee drinking. In part, such variability is due to caffeine tolerance, but there is also evidence for a genetic background. Altogether the data reported here provide further evidence for the perception that coffee consumption is associated with beneficial health effects demonstrated for the cAMP enhancement in platelets, known to counteract platelet aggregation. The effects observed for the influence of cellular heme oxygenase (HO) are in line with the well documented antioxidative activity of coffee and its constituents.
- Development of New Methods for the Synthesis of Aldehydes, Arenes and Trifluoromethylated Compounds (2012)
- In the 1st project, successful development of 2nd generation of a palladium catalyst for the selective hydrogenation of carboxylic acids to aldehydes was accomplished. This project was done in cooperation with Dipl. Chem. Thomas Fett from Boeringer Ingelheim, Austria. The new catalyst is highly effective for the conversion of diversely functionalized aromatic, heteroaromatic and aliphatic carboxylic acids to the corresponding aldehydes in the presence of pivalic anhydride at 5 bar hydrogen pressure, which was otherwise achieved either at 30 bar of hydrogen pressure or by using waste intensive hypophosphite bases as reducing agent. Our method has increased the synthetic importance of this valuable transformation. Selective hydrogenation of carboxylic acids to the corresponding aldehydes is now possible with industrial hydrogenation equipment as well as laboratory scale glass autoclaves. It might also convince the synthetic organic chemists to use this transformation for routine aldehyde synthesis in the laboratories. In the 2nd project, a microwave assisted Cu-catalyzed protodecarboxylation of arenecarboxylic acids to arenes is achieved. This work was done in collaboration with Dipl. Chem. Filipe Manjolinho under the supervision of Dr. Nuria Rodríguez. In the presence of 1-5 mol% of inexpensive CuI/1,10-phenanthroline catalyst generated in situ under microwave radiations, diversely functionalized arenes and heteroarene carboxylic acids have been decarboxylated to the corresponding arenes in good yields at 190 °C in 5-15 min. The loss of volatile arenes with the release of CO2 is controled by the use of sealed high pressure resistant microwave vessels. These reactions are highly beneficial for parallel synthesis in drug discovery due to their short reaction time. Microwave technology will also help in the future to develop more effective catalysts for protodecarboxylation rections. Based on the microwave assisted protodecarboxylation strategy, decarboxylative coupling of arenecarboxylic acids with aryl triflates and tosylates was also conducted under microwave radiation which provided higher yields of the corresponding biphenyls from deactivated substrates in short reaction time compared to the conventional heating. In the 3rd project, crystalline, potassium (trifluoromethyl)trimethoxyborate was successfully applied for the synthesis of benzotrifluorides under the oxidative conditions. This project was done in cooperation with Dipl. Chem. Annette Buba. In the presence of Cu(OAc)2 and molecular oxygen, arylboronates were coupled with K+[CF3B(OMe)3] in DMSO at 60 °C. A variety of benzotriflurides was synthesized in good yields under the optimized reaction conditions. This protocol for the oxidative trifluoromethylation of arylboronates is the base for the development of decarboxylative trifluoromethylation reaction of arenecarboxylic acids. The 4th project discloses the simple and straightforward synthesis of trifluoromethylated alcohols by nucleophilic addition of potassium (trifluoromethyl)trimethoxyborate to carbonyl compounds. This project was done in cooperation with Dr. Thomas Knauber and Dipl. Chem. Annette Buba. In the presence of K+[CF3B(OMe)3] in THF at 60 °C, diversely functionalized aldehydes and ketones were successfully converted into the corresponding trifluoromethylated alcohols. The 3rd and 4th projects demonstrate the successful establishment of crystalline and shelf stable potassium (trifluoromethyl)trimethoxyborate as highly versatile CF3-source in nucleophilic trifluoromethylation reactions. These new protocols are characterized by their user-friendliness and broad applicability under mild reaction conditions, thus they are beneficial for late stage introduction of CF3-group into organic molecules.
- Immobilization of Functionalized Triphenylphosphine Ligands and their Complexes for Application in Catalysis (2011)
- The present PhD thesis is mainly focused on synthesis, characterization and catalytic application of functionalized triphenylphosphine (TPP) ligands and their complexes. We developed a simple and effective strategy to immobilize TPP: A methylester group attached to one of the phenyl rings of TPP allowes the derivatization of the ligand with 3-trimethoxysilylpropylamine, a typical silane coupling agent used for the covalent immobilization of organic compounds on silica surfaces. The resulting functionalized TPP was further coordinated to Pd, Rh and Ru precursors to achieve homogeneous complexes which can be tethered on silica by the post synthetic grafting method and co-condensation method. The obtained heterogeneous catalysts exhibited excellent activity, selectivity and reusability in Suzuki, hydrogenation and transfer hydrogenation reactions. In order to investigate the stability of the catalysts, different types of characterizations such as TEM, solid state NMR of the used catalysts as well as AAS of filtrate and leaching tests were carried out. The results prove the practicability and efficiency of our method. This strategy was further modified to generate an anionic side chain linked to the TPP core by simply replacing the trimethoxysilylpropylamine group by sodium(3-amino- 1-propanesulfonate), which allowes the immobilization on imidazolium modified SBA-15 through electrostatic interaction. The obtained material was further reacted with PdCl2(CNPh)2 and the resulting hybrid material was used for the hydrogenation of olefins allowing mild reaction conditions. The catalyst shows excellent activity, selectivity and stability and it can furthermore be reused for at least ten times without any loss of activity. TEM images of the used catalyst clearly show the absence of palladium nanoparticles, proving the high stability of the palladium compound. By AAS no palladium could be detected in the products and further leaching tests very- fied the reaction to be truly heterogeneous. This concept of non-covalent immobili- zation guarantees a tight bonding of the catalytically active species to the surface in combination with a high mobility, which should be favorable for other catalyses.
- The Role of 17beta-Estradiol on 2,3,7,8-Tetrachlorodibenzo-p-dioxin-mediated Oxidative DNA Damage in Liver Cell Models (2009)
- 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a highly toxic and persistent organic pollutant, which is ubiquitously found in the environment. The prototype dioxin compound was classified as a human carcinogen by the International Agency for Research on Cancer. TCDD acts as a potent liver tumor promoter in rats, which is one of the major concerns related to TCDD exposure. There is extensive evidence, that TCDD exerts anti-estrogenic effects via arylhydrocarbon receptor (AhR)-mediated induction of cytochromes P450 and interferes with the estrogen receptor alpha (ERalpha)-mediated signaling pathway. The present work was conducted to shed light on the hypothesis that enhanced activation of estradiol metabolism by TCDD-induced enzymes, mainly CYP1A1 and CYP1B1, leads to oxidative DNA damage in liver cells. Furthermore, the possible modulation by 17beta-estradiol (E2) was investigated. The effects were examined using four different AhR-responsive species- and sex-specific liver cell models, rat H4II2 and human HepG2 hepatoma cell lines as well as rat primary hepatocytes from male and female Wistar rats. The effective induction of CYP1A1 and CYP1B1 by TCDD was demonstrated in all liver cell models. Basal and TCDD-induced expression of CYP1B1, which is a key enzyme in stimulating E2 metabolism via the more reactive formation of the genotoxic 4-hydroxyestradiol, was most pronounced in rat primary hepatocytes. CYP-dependent induction of reactive oxygen species (ROS) was only observed in rodent cells. E2 induced ROS only in primary rat hepatocytes, which was associated with a weak CYP1B1 mRNA induction. Thus, E2 itself was suggested to induce its own metabolism in primary rat hepatocytes, resulting in the redox cycling of catechol estradiol metabolites leading to ROS formation. In this study the role of TCDD and E2 on oxidative DNA damage was investigated for the first time in vitro in the comet assay using liver cells. Both TCDD and E2 were shown to induce oxidative DNA base modifications only in rat hepatocytes. Additionally, direct oxidative DNA-damaging effects of the two main E2 metabolites, 4-hydroxyestradiol and 2-hydroxyestradiol, were only observed in rat hepatocytes and revealed that E2 damaged the DNA to the same extent. However, the induction of oxidative DNA damage by E2 could not completely be explained by the metabolic conversion of E2 via CYP1A1 and CYP1B1 and has to be further investigated. The expression of low levels of endogenous ERalpha mRNA in primary rat hepatocytes and the lack of ERalpha in hepatoma cell lines were identified as crucial. Therefore, the effects of interference of ERalpha with AhR were examined in HepG2 cells, which were transiently transfected with ERalpha. The over-expression of ERalpha led to enhanced AhR-mediated transcriptional activity by E2, suggesting a possible regulation of E2 levels. In turn, TCDD reduced E2-mediated ERalpha signaling, confirming the anti-estrogenic action of TCDD. Such a modulation of the combined effects of TCDD with E2 was not observed in any of the other experiments. Thus, the role of low endogenous ERalpha levels has to be further investigated in transfection experiments using rat primary hepatocytes. Overall, rat primary hepatocyte culture turned out to be the more adaptive cell model to investigate metabolism in the liver, reflecting a more realistic situation of the liver tissue. Nevertheless, during this work a crosstalk between ERalpha and AhR was shown for the first time using human hepatoma cell line HepG2 by transiently transfecting ERalpha.
- Environmentally Benign Synthesis of Enamides via Waste-Free Catalytic Addition of Amides to Terminal Alkynes (2010)
- A number of natural products are known that contain an enamide as a key structural feature. This functionality is a very important subunit in various biologically active products and pharmaceutical drug lead compounds. In addition, enamides serve as highly versatile synthetic intermediates, particularly in the pericyclic reaction, formation of heterocycles, cross-coupling and in asymmetric synthesis. As a result, several protocols have been devised for the preparation of enamides. Traditional syntheses include condensation of aldehydes and ketones with amides or from hydroxylamines and acetic anhydride, require harsh conditions and yield mixtures of E/Z products. Several metal catalyzed approaches have been also investigated, such as isomerization of N-allylamides and catalytic cross-coupling of amides with vinyl halides or pseudohalides. These protocols proceed under milder conditions but suffer from the limited availability of these starting materials. The research described in this dissertation focuses on efficient and atom-economic preparation of enamides and thioenamides, using readily available starting materials. We developed catalyst systems generated in situ from bis(2-methallyl)-cycloocta-1,5-diene-ruthenium(II), phosphines and Lewis acid or base, efficiently catalyze the addition of primary amides and thioamides to terminal alkynes with exclusive formation of the anti-Markovnikov products in high yield and stereoselectivity under mild reaction conditions. The generality of the newly developed methodologies is demonstrated by common functional group tolerance. Furthermore, Markovnikov products were formed via phosphine-catalyzed addition of cyclic amides to phenylacetylene derivatives. The hydroamidation protocol of primary amides was successfully used in the synthesis of naturally occurring compounds, such as alatamide, lansiumamide A, botryllamides C and E, and the key intermediate in the synthesis of aristolactam. In order to investigate the reaction mechanism, the addition of various amides and carboxylic acids to terminal alkynes was performed using deuterium labeled starting materials and followed by in situ NMR and GC-MS studies.


text:
Product no. 171484
Ghostbusters Slimer Marshmallows 200g
Ghostbusters Slimer Marshmallows are great for Halloween parties!
Our website uses cookies to help us improve the website for you. If you'd like to know more about this, please read our cookie policy.
Product no. 171484
Click to add yours!
(No ratings yet!) ( ratings)
Ghostbusters Slimer Marshmallows are great for Halloween parties!
Please note that not all products are available at all stores and some products are seasonal.
Viewing this site on a mobile device? Switch to the mobile version >© Poundland Limited 2006 - 2017. Poundland Limited Registered in England. Company No: 2495645 Registered Office: Wellmans Road, Willenhall, West Midlands, WV13 2QT


text:
Busting the green products cost more myth/
Here at ECO-Buy, we frequently get asked the question, "do green products cost more?" The simple answer is: NO.
Like many new technologies when first introduced to the market, green products' costs may start high. But as demand increases and technologies improve, costs reduce quickly. Solar panels are a good example, with prices falling from around $10 per watt in 2000 to around $1-2 per watt in 2012 (not including incentive schemes). Alongside this there is the rapidly rising cost of energy, which means that energy efficient products and independent sources of energy become even more attractive. Thus these often outdated impressions of the former cost create a lingering misconception while true costs become increasingly competitive.
Some green products remain more expensive up front due to the materials and processes that must be used to avoid environmental impacts. Even still, these products can still be less expensive if you look at them on a whole-of-life basis. The use and disposal costs of many products can significantly outweigh any difference in purchase price. These may include commissioning, energy, consumables, regular maintenance, and disposal levies.
On the other hand, many of the common characteristics of sustainable products consequently save money, such as:
- Energy and water efficiency;
- Reduced use of consumables;
- Lower hazardous material content;
- Longer life and greater upgradeability;
- Reduced packaging and waste; and
- Ease of recycling.
Marks & Spencer recently released their 2012 corporate social responsibility report, in which they revealed their sustainability program, Plan A, had actually saved them £105 million over the last year. When the plan was introduced in 2007, they expected it to cost the company around £200 million, but by year 3 they had started seeing a financial benefit from increased efficiency and better management. Procurement initiatives like replacing corporate fleet with greener vehicles, streamlined logistics, upgrading delivery fleet, reducing packaging, use of video conferencing over travel, buying green IT equipment, energy efficient store fit-outs, and buying and generating renewable energy all added to the savings. See more on the business case behind Plan A here.
Many companies' 2 or 3 year payback requirement would prevent them from realising these benefits, actually costing the company in the long run. We recommend all purchases be evaluated on their total cost of ownership (TCO), which incorporates the purchase price, operation, maintenance and disposal.
Sustainable purchases do, of course, come with a number of environmental and social benefits, which all add to the triple bottom line.
ECO-Buy can help your organisation with whole of life costing, establishing the business case for green products, and other sustainable procurement needs. Contact us for details or advice.
Article provided by Sara Redmond-Neal, ECO-Buy Business Program Manager.


text:
Diner's Delight
Serving delicious soul food since 1962. Specialties: glazed chicken, oxtails, catfish, beef ribs, peach cobbler, greens, yams, and dumplings.
TripAdvisor Rating6 Reviews | Write a Review
Great neighborhood restaurant..Reviewed By Cliff B November 2016
Food is excellent. Patience is required while waiting in line to select food and pay for food. The restaurant is clean with lots of seating for 50 customers. Parking is also convenient.Full Review
Sweetie Pies too crowded? Try Diner's DelightReviewed By KimberlyAKA September 2016
We planned to go to Sweetie Pies but the line was hours long so we found Diner's Delight by googling soul food. It was so good. Lots of food for the money. The yams were the best. Pork chops also...Full Review
Everyone has a bad dayReviewed By Chris M February 2016
This was not my first time here, in the past I had better meals. Went for Sunday dinner and I had the baked chicken, okra and mac& cheese. Was not all the happy but was decent enough to eat. I will...Full Review