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AZURE magazine launches international
design competition
AZURE, the contemporary design and architecture magazine, is marking its 25th anniversary year by launching an annual international design competition. The AZ Awards will honour top-tier architecture firms and design studios that have produced outstanding work in the past year. The competition will be adjudicated by a panel of international jurors.
AZURE is known for spotlighting innovation and talent in various design-related fields, including industrial design, commercial and residential architecture, interior design and landscape design.
Professionals and students are invited to submit previously unawarded and unpublished works completed by December 31, 2010, in five categories: industrial design, architecture, interior, concepts and A+ (student) work. Submissions are open January 1, 2011 through March 1 and winners will be published in the summer issue of the magazine.


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MS Human Biology Faculty
Dr. John H. LangdonProfessor of Biology & Anthropology
Expertise in human biology, human anatomy and human evolution
PhD, Anthropology
Areas of Expertise
human evolution; human anatomy; human biology
Dr. Langdon has written three books, The Human Strategy: An Evolutionary Perspective on Human Anatomy (Oxford University Press), Human Dissection for the Allied Health Sciences (Little, Brown), and Functional Morphology of the Miocene Hominoid Foot (S. Karger), and co-edited a fourth, The Natural History of Paradigms (University of Indianapolis Press). He is currently working on a project to reconstruct the human biological history of Franklin County, IN.
Research Interests
historical demography; human biology; human evolution; functional and evolutionary morphology; history and development of paleoanthropology; evolution of human behavior; history and process of the natural sciences
PhD, Anthropology, Yale University
MPhil, Anthropology, Yale University
BA, Anthropology, Harvard University
Fun fact
I appear to be the go-to skeptic on the Aquatic Ape Hypothesis for journalists around the world.
Favorite thing about UIndy
The opportunity to mentor a graduate student through a thesis and into a doctoral program.
Contact Information
Esch Hall, 233D
Dr. Krista E. LathamAssociate Professor of Biology & Anthropology
Director, Molecular Anthropology Laboratory
Co-Director, Archeology & Forensics Laboratory
Expertise in molecular and forensic anthropology
PhD, Anthropology
Areas of Expertise
molecular and forensic anthropology
Dr. Latham has supervised numerous research projects with undergraduate and graduate students investigating the transfer of DNA to objects and how that can impact criminal investigations, as well as various aspects of skeletal analysis. Additionally, she has conducted fieldwork with UIndy students in Santiago, Chile and South Texas. Dr. Latham recently co-edited a book entitled Age Estimation of the Human Skeleton which compiles different techniques used to estimate age at death of the skeleton. She is a Fellow of the American Academy of Forensic Sciences and a Board Certified Forensic Anthropologist (D-ABFA). She currently serves as a Consulting Forensic Anthropologist for police, coroners and pathologists in the Midwestern United States and has delivered numerous lectures for state and local agencies around the country. Dr. Latham also serves as a DNA Expert in the U.S. Federal Court System.
Research Interests
investigation of different aspects of skeletal biology; population genetics; skeletal DNA
PhD, Anthropology, Temple University
MA, Anthropology, Temple University
MS, Human Biology, University of Indianapolis
BS, Biology, University of North Texas
Fun fact
My favorite food is nachos.
Favorite thing about UIndy
The people!
Contact Information
Good Hall, 017C
Dr. Stephen P. Nawrocki
Sease Distinguished Professor of Forensic Studies & Professor of Biology
Honorary Professor of Anatomy, University of Pretoria, South Africa
Expertise in skeletal biology, forensic anthropology, osteoarcheology, and more
PhD, Anthropology
Areas of Expertise
skeletal biology; forensic anthropology; human taphonomy; osteoarcheology; skeletal age estimation; biostatistics; historic cemeteries
Dr. Nawrocki has taught full-time at the University of Indianapolis since 1991, where he is currently a tenured professor of biology and anthropology, serves as the Director of Osteology at the Archeology & Forensics Laboratory, and is also the Director of the Master of Science in Human Biology program. One of only 60 board-certified forensic anthropologists in North America, Dr. Nawrocki has served as a consultant on hundreds of human remains cases in Indiana and Illinois and has delivered numerous lectures at educational seminars around the country. In 1999, Dr. Nawrocki was named "Teacher of the Year" at the University of Indianapolis, where he also received the Booker Teaching Award for the Sciences in 1993. Dr. Nawrocki has authored several books and has published in journals including the Journal of Forensic Sciences and Florida Anthropologists.
Research Interests
analysis and identification of human skeletons; environmental processes affecting buried and scattered bones (taphonomy); evidence recovery from outdoor crime scenes (forensic archeology)
PhD, Anthropology, State University of New York at Binghamton
MA, Anthropology, State University of New York at Binghamton
BA, Anthropology & Psychology, University of Maine at Orono
Fun fact
In his spare time, Dr. Nawrocki plays guitar in his church band and enjoys birding and hiking with his family.
Contact Information
Good Hall 008

subset: commoncrawl


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Goldilocks Bakeshop
439 Shaw Blvd. cor. Ideal St., Mandaluyong, Metro Manila
- 8 Reviews
- 13 Recommend
- 7 Reviewers
Primary Details
- Category:
- Bakery
- Phone
- +6327238440
More Info
Price Range
₱55 - ₱605
Most Recent Reviews
The fresh lumpia was nice and the sauce was caramely and yummy. The palabok was rather bland and required lots of patis and kalamansi.
- No. of Comments: 0
- No. of Likes: 2 Likes
Don't break my heart. My achy breaky heart.
Goldilocks Caramel Pusong Mamon
Decorate your cake (Mamon) with sprinkles and caramel.
It really brings out the creativity in you. Good for all ages. Kids will surely love it.
It's an ordinary Mamon where you can apply your art skills in order to make the Mamon into something extraordinary.
After all, it's the decorating part that makes this Mamon special.
Goldilocks. You're the one!
- No. of Comments: 0
- No. of Likes: 2 Likes
This dining GL place is big enough. i love their Dinuguan with rice especially when i'm super hungry! I paired it with Pork BBQ! Busog!
- No. of Comments: 0
- No. of Likes: 1 Like
If only for the dinuguan, we wouldn't come back here again.
What happened to your serving sizes? I think that you can go a price hike rather than stay at your prices but minimize the servings. Felt like my food didn't go down my instestines.
Great food but with having false ads on your serving sizes, you wouldn't be good after all.
Maybe that's the reason there were no queue during lunch time.
- No. of Comments: 5
- No. of Likes: 3 Likes
Okay, enough of cakes. Let's talk about their menu besides cakes.
#1 Dinuguan
They never fail to make such awesome dinuguan. They serve a little though.
If you're a fan of Dinuguan or Looking for Home made-like foods, try here!
Speed of service isn't good but don't hesistate to ask for your request. Maybe they are just like that, not being attentive to the needs of the customers.
Other than that, it is a nice place, no hassle queue and cozy type.
- No. of Comments: 2
- No. of Likes: 3 Likes
One of my mom's favorite restaurants that we used to dine-in every time we go to mall is Goldilocks. Ever since when we are still kids she used to bring us to Goldilocks.
She loves to order here is Lumpiang Sariwa or Fresh Lumpia. Yes, she's a number one fan of Goldilocks. Given that the food is healthy, because it's composes of veggies, the taste is great also. We enjoyed the sweet sauce garnished all over and those crushed peanuts made the taste perfect.
They are one of the best and affordable bakeshop I've ever known since I was a kid. Now that I am old enough I still love their breads and goodies. Great pasalubong nook for our loved ones.
- No. of Comments: 0
- No. of Likes: 9 Likes
not pleasing when you see it but the moment u taste it, super yummy!!
- No. of Comments: 0
- No. of Likes: 1 Like
The best dinuguan in town. :) forever favorite. :)
- No. of Comments: 1
- No. of Likes: 3 Likes


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Huge Botfly Maggot Removed from Head MP3
A souvenir from Panama, it was growing in my head for a month before it was big enough to pull out....Yeah its a little bit disgusting but I added some Vivaldi so ...
Gusano en la cabeza / head worms MP3
Gusano en la cabeza / head worms Gusano en la cabeza / head worms Gusano en la cabeza / head worms Gusano en la cabeza / head worms Gusano en la ...
Big Worms for Bass Fishing - How to series. Giant shaky head worms. 🎣🐛🐛🐛 MP3
http://www.ScottMartinChallenge.com - Watch Scott Martin show you an alternative way of rigging big worms for fishing deep or in the heat of the summer for ...
Headworms MP3
Provided to YouTube by The Orchard Enterprises Headworms · Uzi & Ari Headworms ℗ 2008 Own Records Released on: 2008-10-15 Auto-generated by ...
A worm in the foot Amazing!! (Un gusano en el pie) MP3
Worms in live human... MP3
This video was uploaded from an Android phone.
Obscura - Headworm MP3
This band is fucking incredible, support them! All rights go to Obscura and Relapse Records. Music is from Obscura, not from me. MySpace ...
Lenz Headworms MP3
The_PsychoActive_RadioStatioN http://www.psytube.at _ Tune_into_Drop_ouT___ ___ Download App for Android or iOS.
[HD 1080p] Mikrogeophagus altispinosus - mit Fräskopfwürmer / Milling head worms (Camallanoidea) MP3
Diagnose: Rote Fäden, die aus dem After hängen und sich selbstständig bewegen. Bei Zierfischen sind andere Ursachen für dieses Bild nicht bekannt.
Rodney Rogers Outdoors - Ep.2: Shakey Head Worms - MP3
Rodney demonstrates how to rig a Shaky Head Worm.
Dollar tree war head worms taste test MP3
New species? Medusa head worms that appear unknown MP3
In Austin,Tx, these appeared in our koi pond and are all over roots in the water. Ive yet to learn what species they are.If u know anything lemme know in the ...
Doug Carthel spraying milo for headworms MP3
Headworms MP3
Provided to YouTube by Believe SAS Headworms · Lenz Split Brain ℗ Mind Expansion Released on: 2009-08-06 Composer: DR Music Publisher: D.R ...
Head to Head: Worms: Revolution #2 MP3
In this quiet time for game releases we took a break from two minute reviews and brought back our summer series! Head to Head returns with some worms!
Obscura - Headworm - live in Munich, 2007-09-29 MP3
Obscura performing "Headworm" live at the Titanic City, Munich, Germany Recorded September 29th 2007 during the Blasting Diversity Tour 2007 Line up: ...
Huge Botfly Maggot Removed from humans skin - botfly extraction parasite MP3
bot fly removal | botfly infestation | botfly extraction | botfly in head | botfly in dogs | botfly larvae Thanks for watching ! If you like the video , please click the like ...
Head to Head Worms 2: Armageddon - Rope Race MP3
Back in Worms 2 for another Head to Head between Ben, Dan and Rob. Watch them win and fail at the rope swinging. Who will come on as the winner?
The Observatory - Headworm MP3
Singapore's indie band.
Limbo (Part 5) - HEADWORM MP3
SUBSCRIBE for stuff after the HO-tel!
Shakey head floating worms MP3
Which popular worms have tails that float on a shakey head rig? Check out the results.
World's Weirdest - Larva Removed from a Girl's Scalp MP3
Meet a pest that can really get under your skin... or in your head. The parasitic botfly lays its eggs in "vector hosts' — including humans! Removing the hungry ...
Headworm (live) - The Observatory MP3
The Observatory @ The Substation, Singapore Catacombs Release Show 20th Apr 2012.
Tony V - Headworm MP3
Send in the Worms!! - Head2Head plays Worms MP3
It's another week of Head 2 Head and the nerds have picked a bit of a classic game, in my opinion. Worms. And in the interest of fairness (I'm not actually sure if ...
Worm inside your head MP3
Beware of the worm.
Worms - Head2Head MP3
Steve has challenged Champion Trisha to a single round of Worms on the XBox360. The loser has to eat several of the hottest buffalo wings we could find.


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- throat
- I. noun Etymology: Middle English throte, from Old English; akin to Old High German drozza throat Date: before 12th century 1. a. (1) the part of the neck in front of the spinal column (2) the passage through the neck to the stomach and lungs b. (1) voice (2) the seat of the voice 2. something resembling the throat especially in being an entrance, a passageway, a construction, or a narrowed part: as a. the orifice of a tubular organ especially of a plant b. the opening in the vamp of a shoe at the instep c. the part of a tennis racket that connects the head with the shaft 3. the curved part of an anchor's arm where it joins the shank — see anchor illustration II. transitive verb Date: circa 1611 1. to utter in the throat ; mutter 2. to sing or enunciate in a throaty voice
New Collegiate Dictionary. 2001.


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Question: In this section we introduced a descriptive measure of the
In this section, we introduced a descriptive measure of the utility of the regression equation for making predictions. Do the following for that descriptive measure.
a. Identify the term and symbol.
b. Provide an interpretation.
View Solution:
a. Identify the term and symbol.
b. Provide an interpretation.
View Solution:
Answer to relevant QuestionsFill in the blanks. a. A measure of total variation in the observed values of the response variable is the _________. The mathematical abbreviation for it is _________. b. A measure of the amount of variation in the observed ...y-bar = −3 + 2x a. Compute the three sums of squares, SST, SSR, and SSE, using the defining formulas (page 164). b. Verify the regression identity, SST = SSR + SSE. c. Compute the coefficient of determination. d. Determine ...Following are the data on plant weight and quantity of volatile emissions from Exercise 4.53. a. Compute SST, SSR, and SSE, using Formula 4.2 on page 167. b. Compute the coefficient of determination, r2. c. Determine the ...For each of the sums of squares in regression, state its name and what it measures. a. SST b. SSR c. SSE In the context of regression analysis, what is an a. Outlier? b. Influential observation?
Post your question


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View Official IMDb Resume Photos »
Photo Gallery
Born in Ajax, Ontario, Corey's career in front of the camera began as a baby model at the tender age of six months. Modelling soon led to work in commercials. At seven years old, he landed his first acting job in the ABC mini-series "Family Pictures", alongside screen veterans Angelica Houston and Sam Neill. The experience convinced young Corey ... See full bio »


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A perfect table setting requires pristine linens and polished cutlery, except at off-Broadway restaurants, where waiters set every table in postapocalyptic Vienna. Avoid avant-garde eating with this Groupon.
$8 for $16 Worth of Mexican Food and Drinks
Chefs prepare classic Mexican dishes such as spinach-and-cheese enchiladas ($6.50), asada burritos filled with grilled pieces of lean steak ($7.95), and the Acapulco platter festooned with shrimp and carne asada ($8.95).
Speedy Gonzalez
The vision behind Speedy's is simple: fresh Mexican fare served fast and free of pretension. Chefs plate dishes ranging from taco salad with a crispy shell to deep-fried burritos, plus specialty items including the signature deep-fried boneless chicken paired with honey bread. The Dining room is a Fiesta decor, where you can come and enjoy your favorite dish in a Mexican fiesta atmosphere!


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This is a split board - You can return to the Split List for other boards.
Do you Guys think PC gaming will ever be as 'mainstream' as consoles?
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|2,900 sq. ft.
|Property type
|Minimum Stay
|3 nights
Adorable, updated, and spotless 2,900 square foot lakefront home that overlooks the sunsets on Lake June. New appliances, cabinets, quartz countertops in the kitchen. Lake June has approx. 3,600 acres and is excellent for family bonding, fishing and water sports. This home is full of fine furnishings, decorations, and supplies. Not you average rental, but, rather a second home to us and lovingly appointed even down to the crystal wine glasses.
This house is on the best part of the lake with large views and is across from the reserve. Huge screened in porch with rocking chairs and ping pong table. The house is loaded with games and puzzles. House, Kitchen, bathrooms have been updated and freshly painted. A very private, hot watered exterior shower has just been added and is so relaxing. An outdoor fire pit makes awesome family memories under the stars. Everything you need is in this spotless house. Home sits on almost an acre and is a distance from the road so you feel safe with your children. Nice boat house with outdoor seating, picnic table, and a rope swing for hours of fun. Large grill and cook-top for outside use. This nicely decorated house will offer memorable vacations! Just an hour from the new Lego Land and a hour and a half from Disney, but, you won't want to leave this lake.
This new boat house has a lift for a ski boat (may be owner occupied), and another exterior boat slip. Owners jet ski and wakeboard boat are not available for rent.
Keywords: House, lakefront, fishing, Disney, Lego Land, boathouse, acre, boating, home, skiing, wakeboarding, paddleboarding, canoe,
We are a Miami based family and are all world and nationally ranked wake boarders. This lake house is a huge escape for us and is the making of wonderful childhood memories.
Paula purchased this house in 2008
We bought our home on Lake June after vacationing there for over ten years. It was by far our favorite and cheapest vacation we took with our family. Nothing beats the memories made on this lake. We finally purchased our second home there and decided it would be great to share with a few select renters.
We love this house with its huge screened in porch and rocking chairs looking at the lake. Also love that we are close to the lake and it is a flat walk across the lawn to get to water. We were sold on the huge oak trees in the back yard. Also, our main family room for eating and cuddling up on the couch for TV has windows on three sides of the room. This home is the perfect charming lake house.
2nd year we have stayed in a house in this area for our week long venture to Sebring. This place was great. It was right on the lake, bedrooms were as described and comfortable. Wouldn't change a thing about the house. It was well cared for and included everything we needed for our week. The owner was prompt with replies answering any questions we had. Would stay here again
Having lived off Lake June for many years and taking advantage of its beauty, it was very special to spend four nights in this home on the lake.
It was the ultimate experience of spaciousness, cleanliness and well provided and cared for. Our family couldn't get enough of the views, convenience, swimming and fishing literally right outside the door. We were also able to take advantage of outdoor grilling, s'mores at the fire pit and great family time in the well appointed family, tv, and dining area. Everything you could possibly want or need is here. I can't wait to select a date for next year and book our next family vacation. It literally doesn't get any better than this. Thank you to the owners for sharing this remarkable home with us!
This home was beautiful! Very clean and open. The view of the lake was gorgeous..we loved sitting on the dock watching the sunsets. Our teenage daughters spent many hours on the rope swing and swimming in the lake. It was very peaceful. They had lots and lots of great games and puzzles which my family enjoyed doing at night. We had a great week spending quality time together and look forward to staying here in the near future.
The Waters family
The Lake June home had everything we needed. Plenty of room for our family of 10!
The house is very nice, clean, updated and on a beautiful spot on Lake June. The boathouse is very well kept and clean, a great spot for morning coffee in the adirondack chairs.
There is a great screened porch which looks out over the lake with rocking chairs. We have rented many houses in Lake Placid, this is by far the best so far. We can't wait to return!
The accomdations were outstanding! House is well maintained and clean, more than just a lake rental house. Owners were responsive with any and all questions. Looking forward to next summer.
Just one hour from the new Lego Land and 1.5 hours from Disney. Lake Placid was voted Reader's Digest 2013 Most Interesting Town in the USA as it is loaded with story telling murals all over the town with accompanying museum. Lake Placid is also the Caladium capital of the world and the fields are beautiful.
|Cleaning Fee
|Damage Insurance
|Damage Deposit


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This month I read Push by Sapphire.
Push is about a sixteen year old, African American girl, named Precious, living in Harlem, who lives with her welfare-collecting mother and has already had two children, both by her biological father who is out of the picture in her home life.
Push is written in an intentionally uneducated style, with poor grammar and even worse spelling as it is told from the point of view of the protagonist, Claireece Precious Jones, names such by her mother because "As soon as I held her, I knew that's what she was. Precious."
The book starts off with Precious being kicked out of her school for being pregnant with her second child and being offered a spot at an alternative school so she may get her GED. In her GED class preparatory classes, she meets an inspiration teacher, Blue Rain (yes, her first name is Blue) and proceeds to begin adjusting to her life as something more than just her mother's slave.
Push really opens your eyes to the real tragedies of life that you, as the reader, are aware are going on out in the real world. From incestuous-rape relationships to teen pregnancy to child abuse to welfare abuse to inadequate school systems, the sadness of this book affects you deeply.
If you want to read a book that will make an impact on your life and the way you think, I recommend this book greatly.
(my middling attempt at recreating the movie poster)
Have you read this book? What did you think?
Views: 110
I only know of this book via the movie "Precious, based on a novel Push by Sapphire," as the title goes. From the movie, I had an idea that it was about an African American girl with a horrible life. I didn't really know much about the movie beyond that, besides Gabourey Sidibe-mania and Mariah Carey's drunken acceptance speech. Anyways, I'm pretty interested in reading this book; it sounds very powerful, albeit depressing. I wonder how the purposeful spelling/grammar issues would affect my reading (since I'm usually pretty intolerant of poorly written English).
I only saw the movie and haven't read the novel yet. The intentional grammar errors don't really translate perfectly from the book to the movie, so reading Push in its original format sounds like a more convincing experience. I think it's interesting how the author would do this on purpose, it must add a whole lot to the imagery.
I remember when the movie came out and me being horrified that her own father did that to her. I'm glad that you wrote a blog about this book or else I would've missed out on a good book! It's true that people should be aware of the real tragedies that go on everywhere and every day because it makes people become less ignorant which in turn makes the world a little better to live in.
I find this book as an interesting contrast to Crank, in which the protagonist had the capability to avoid her fate but chose not too, while here, the protagonist had misfortune dealt upon herself and is constantly trying to escape her fate.
Christopher, while it was originally a bit hard to understand, it gets progressively gets better throughout the book, symbolizing her educational growth. But I do think it adds a lot, when you read it you can really feel the inflection and the accent.
I clicked on this because I was so intrigued by the title. Now I am compelled to read the book. Nice blog post, Sophia!
Great blog! I'll be sure to check out Push. This reminds me of Flowers for Algernon because the grammar and spelling in it starts off poor then gets better as the protagonist gets more educated.


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6 ways to protect your credit after a natural disaster
Ignoring bills can hamper your recovery
By Tamara E. Holmes | Updated: August 18, 2016
Have you fled a wildfire? Still bailing water out of your basement post-flood? If you are rebuilding your home or life after a natural disaster, the last thing you want to think about is whether you paid your credit card bill on time.
Putting such mundane tasks as paying bills on the back burner while you attend to more important issues -- such as finding temporary housing, for example -- would seem to be the most logical course to follow, but it's not, financial experts say. "A consumer's delinquent payments could ruin their credit score at a time when they need access to credit the most," says Melinda Opperman, chief relationship officer for Springboard Nonprofit Consumer Management Inc., based in Riverside, Calif.
While assessing property damage, calling insurance companies and applying for government disaster assistance may be top of mind, here are the steps you should be taking simultaneously to keep your old debts from destroying your financial future.
1. Get a copy of your credit report. One of the first things you should do after a disaster is get a copy of your credit report -- a move that could help you tremendously in the future, says Tom Quinn, vice president of business development at myFICO.com. If the disaster causes financial difficulties, your credit score may plunge. By having a copy of the credit report before it reflects any financial impact resulting from the disaster, you can later make the case to a lender or someone else checking your credit -- such as a potential landlord -- that the disaster, not financial mismanagement, caused your low credit score, Quinn says. You can get a free credit report each year from each of the three big credit bureaus (Experian, Equifax and TransUnion) by visiting AnnualCreditReport.com.
A consumer's delinquent payments could ruin their credit score at a time when they need access to credit the most.
Melinda Opperman
Springboard Nonprofit Consumer Management
2. Create a post-disaster budget. While you're waiting for a check from your insurance company, take a realistic look at your savings and income. Then look at what you need for the basics such as food and shelter. If your house is destroyed, be sure to cut off costly services, such as electricity, cable TV or Wi-Fi. Your post-disaster budget should be bare-bones. Cut out luxuries until you can get back on your feet, Opperman says. Once you've established a post-disaster budget, you'll know how much you have left to pay on your credit cards and other debts. However, even if you have enough in savings to pay off an entire credit card, you might want to budget minimum payments for a while to conserve cash until your life becomes stable again, Opperman says.
3. Initiate contact with creditors. Once you know how much money you're working with in your new reality, it's time to reach out to your creditors. Sometimes when disasters occur, credit card companies will email their customers to let them know they're aware of the disaster and will waive late fees that month for those who are affected. But don't let the communication stop there. Credit card issuers will often do far more for you if they know about your specific situation, says Natalie Brown, a spokeswoman for Wells Fargo. "Based on the customer's individual situation, those options could include various short- and long-term payment assistance programs or even temporary payment moratoriums," Brown says. When communicating with your creditors, look on a statement or the back of your credit card to get the number and call the creditors directly rather than responding to an email. That way you protect yourself from scammers who may be fraudulently posing as lenders to collect information and possibly steal the identities of disaster victims.
4. Document all conversations. When contacting your creditors, be prepared to tell them how the disaster affected you, how long you think your ability to pay will be impacted and how much you can afford to put toward your bill. Keep a detailed record of the conversation, knowing who you talked to, what they promised and when the phone call took place. To be on the safe side, when talking to a customer service representative, "say, 'I'm going to wait on the phone a moment while you make your notes,'" Opperman says. If a creditor agrees to a major change to the credit agreement, such as a three-month suspension of payments, ask for something in writing.
5. Explain the disaster's effects on your credit report. As you're recovering financially from a disaster, you can add a 100-word statement to your credit report explaining that you experienced a natural disaster and it caused your credit to suffer. While this won't affect your credit score, it lets any creditors who pull your report know what's going on and convey that you're a responsible consumer working to bring any delinquent accounts current. Depending on their policies, they may consider that in any lending decisions. Just remember to revise and eventually remove the 100-word statement as your situation improves so the statement doesn't hinder your borrowing abilities in the future.
6. Look for long-term recovery funding. Your insurance policies and government assistance may help you to rebuild your home or possibly replace your car, but you may have to seek out additional resources to help you pay for other debt obligations, particularly if your job was impacted by the disaster. DisasterAssistance.gov also provides links to short-term and long-term disaster assistance programs that may be able to help you out, or you can try raising funds through social lending/fundraising sites, such as GoFundMe or Fundly.
See related: Video: Preparing your finances ahead of a disaster, Avoid debt through personal fundraising
- 6 times to forgo big rewards for a basic, low-interest card – Why some people eligible for coveted cards are better off turning them down ...
- Protecting the developmentally disabled from credit card debt – Family members can play a key role in safeguarding a loved one's finances ...
- 4 common scenarios for card debt liability after a cardholder dies – Determining who is responsible for the debt lies in the cardholder arrangement ...


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Get Free Product Catalog!
You can order a printed version of our latest catalogue by filling out the online form or download pdf version here.
Swing Metal Frame (double)
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Swing Metal Frame (double)20112
- Price980 €
- Width250 cm
- Length36 cm
- Height210 cm
- Critical falling height140 cm
- Safety zone 735x339 cm
- Falling surfaceRequired
- All prices exclude VAT


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Linked Together Choker- Silver
$ 10.00
Estimated Delivery (US): to (via standard shipping) Shipping Info
This choker is so chic! We love the silver chain look. It has a clamp in the back and is perfect for all your spring looks!
If you are unhappy with your purchase for any reason we will offer a refund. If you are unhappy with the size or color and interested in a exchange, please re-order your desired item online and then simply return your original item for a refund.
For more information, check out our 'Returns' page.


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Special Offers
Learn about the latest deals before everyone else - sign up today!
Ashworth V-Neck Wind Jacket
Regular Price: $120.00
Sale Price: $59.94
You Save 50%
Description: Ashworth V-Neck Wind Jacket. Fabric is 100% lightweight polyester dobby. Be ready for any weather in this water and wind resistant contrast v-neck jacket. Adjust with waistband drawstring and includes contrast Golfman logo on back neck. Colors: Black, Carmine Red, Navy and Stone. Size S-4XL
Production & Shipping Details
Production & Shipping Details
Our graphic design department can help you with your design, and in most cases at no extra charge. Just give us a call or send us an email!
Embroidery, $4.25 Flat Fee.School Purchase Orders
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When you want to live in the heart of the West Village there are not many more central places than on 76 Charles street. In this beautiful studio you will have everything your heart desires without paying the usual sky high prices. It is perfect to live in or if you want your own vacation home away from your current city.
Please write us immediately for a viewing as this will not be on the market long!
Apartment is right next to local celebrities such as Sarah Jessica Parker and is easy walking distance to all of the top restaurants and local hangouts.
-Convection Oven
-Wood floors
- Buvette
-Heat included in the winter
-$30-45 are utilities
-Ground level
-Quiet street
-Tons of bars and cultural activities around


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A delicious and nutritious range of Sprouted Wheat, Rye and Spelt Breads that are also low fat.
Heathly cakes! With no dairy products, eggs, preservatives or sweeteners, these delicious cakes are suitable for vegans.
A range of rye breads made with a sourdough starter and no added yeast. A filling and tasty yeast free alternative to traditional breads
Our Gluten Free products benefit from the long shelf life of all Everfresh products, but with none of the additives found in more commercial lines.


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Closing Soon: Kitchen Classics
Just found out that Kitchen Classics, the long-running store on Thomas Road (4041 E. Thomas), will be closing its doors for good, sometime next week. (They're playing it by ear on the exact day, an employee told me.) Chalk this retail casualty up to the economy, like so many other places.
On the bright side, though, owner Shauna Halawith is continuing to book cooking classes, although they are no longer being held at the store. Visit the website to subscribe to the newsletter to find out about upcoming offerings.
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the type of girl that will burst out laughing because of something
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Police Still Searching Park for a Young Girl
Published: November 19, 1987
More than 30 police officers are to search a park on the Brooklyn-Queens border for a fourth day today in response to a report from three children that they had seen a young girl carried there and left by a man.
A police spokesman, Officer Joseph M. Gallagher, said the search would resume at 8 A.M.
Officers began combing the park Monday afternoon, after the children, ages 8, 12 and 14, said they saw the man enter Highland Park with a child slumped over his shoulder and leave without her. The 141-acre park straddles the East New York section of Brooklyn and Glendale, Queens.


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Progress beyond the state-of-the-art
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Approximately 440,000 cases and 190,000 deaths from breast, ovarian and prostate cancer occurs annually in Europe. The cancers share an underlying aetiology related to sex steroid hormones, and some common inherited susceptibility, such that it is natural to study these diseases together
(1). Breast and prostate cancer have shown an increasing secular trend, indicating that lifestyle is an important determinant of disease risk (2). Notwithstanding the importance of hormonal factors, no large underlying causes have been identified for these cancers, although several important risk factors are known. There is little evidence of infectious aetiology for these cancers. A recently published report from the World Cancer Research Fund indicated that few specific dietary factors play an important role for cancers of the breast, ovary and prostate (3).
It is today not possible to determine the individual risk of cancer. Numerous studies have identified factors that affect the risk of breast, ovarian and prostate cancer but risk estimates have so far only been calculated on an aggregated group level. Little is known of the genetic predisposition needed to develop cancer. Even less is known about how lifestyle factors modify the effect of inherited genetic alterations. Below we describe the current knowledge on risk factors for cancer of the breast, ovary, and prostate.
Breast cancer. Many of the established breast cancer risk factors are associated with exposure to endogenous or exogenous oestrogens and other steroid hormones. Higher levels of circulating oestrogen levels in postmenopausal women have been associated with increased risk of breast cancer (4). Reproductive factors, such as late age at menarche, early age at menopause, childbearing, breastfeeding, and early age at first birth are associated with a reduced risk of breast cancer. They tend to reduce the length of exposure to cyclical high oestrogen levels and thereby life- time exposure to endogenous hormones. Menopausal hormone therapy is effective for the short-term relief of menopausal symptoms but longer term use is associated with an elevated breast cancer risk in postmenopausal women (5). Recent findings support a difference in risk by type of therapy with
combined estrogen-progestagen therapy posing a greater risk than estrogen monotherapy. Risk appears to be restricted to current users. The prolonged use of oral contraceptives is also associated with increased risk of breast cancer, particularly for current use. The association of obesity (body mass index) and physical inactivity with risk elevation points to the importance of energy balance for disease prevention, particularly in postmenopausal women. Additional breast cancer risk factors are benign breast disease history, radiation exposure, and excess alcohol consumption (6).
Although not generally recognised as a risk factor, we showed recently in a meta-analysis that tobacco smoking increases the risk of breast cancer in women with NAT2 slow acetylation genotypes (7). There is recent evidence suggesting that long-term daily use of adult-strength aspirin may be associated with modestly reduced overall cancer incidence. A meta-analysis also supported current evidence that aspirin may reduce risk of breast cancer and may be differential by estrogen receptor status.
Women with a first-degree family member with breast cancer have an increased risk of breast cancer, as have women with a history of atypical hyperplasia or with high mammographic density. Apart from these genetic and endogenous factors, lifestyle factors play an important role in the aetiology of breast cancer (Table 1). Age at menarche is strongly influenced by lifestyle factors, illustrated by trends over time. Age at menarche has been shifted downwards dramatically in western countries during the last century. Most likely, the increasing energy intake and decreasing physical activity of children, contribute to the trend in earlier age at menarche. For age at menopause lifestyle influences are less clear, although smokers tend to reach menopause earlier than non-smokers. An early menarche and a late menopause both independently increase the risk of breast cancer. Thus, the longer women are exposed to menstrual cycles, with their regular high levels of gonadal hormones, the higher their risk of breast cancer.
Reproductive factors constitute another set of established risk factors of breast cancer. The risk is increased with a later first birth, a smaller number of births and a shorter duration of breastfeeding (Table 1). The trend over time in each of these factors has been in the risk increasing direction, explaining a major part of the increasing trend in breast cancer incidence. It has been shown that pregnancies and breastfeeding stimulate the differentiation of ductal and lobular breast cells, which may render these cells less vulnerable for oncogenic influences. However, other mechanisms like effects on the breast stem cells may also be involved.
Although a higher weight is associated with a decreased risk of premenopausal breast cancer, increased weight is an important determinant of the risk of postmenopausal breast cancer. The time trend of increasing body weight, reflecting an increasing positive energy balance, is well known. After menopause oestrogen is no longer produced by the ovaries. The only remaining source of oestrogen is the conversion from androgens in fat cells. In addition, the bio-availability of oestrogen is higher among obese women. Thus, endogenous bio-available oestrogen levels of postmenopausal women with overweight are higher than the levels in women with normal body weight. Several prospective cohort studies have shown that high levels of oestrogens and androgens are associated with a 2-2.5 fold increased risk of developing breast cancer later in life (upper quartile versus lower quartile; Table 1).
Apart from the favourable effects on body fat, physical activity has been shown to lower the risk of breast cancer independently. Dose-response relationships have been found consistently. The biological pathway has not been elucidated so far, but several mechanisms have been suggested, like alteration of sex hormone levels and alteration of immune function.
Given the hormone-related aetiology of breast cancer potential effects of use of exogenous hormones, like oral contraceptives and hormone replacement therapy have extensively been examined. Current use of oral contraceptives is associated with a weakly increased risk of breast cancer, which is independent of duration of use. The increased risk slowly diminishes after stopping of use. Current use of hormonal replacement therapy is also associated with an increased risk, and longer duration of use is associated with increasing risks. Risk elevations are higher for combined preparations than for oestrogen-only preparations. As is the case with oral contraceptives, the risk slowly diminishes after stopping use of hormone replacement therapy. Accordingly, when use of hormone replacement therapy became less popular in the US in 2003, the incidence of breast cancer decreased. The increased risk of breast cancer due to hormonal replacement therapy is smaller or even absent among overweight/obese women. Possibly, use of hormonal replacement therapy provides elevations of hormone levels that are negligible as compared with the already high endogenous hormonal levels in these women.
Ionizing radiation increases risk of breast cancer dose-dependently, especially if women have been exposed at young ages. The IBCCS study reported that BRCA1/2 carriers were found to have increased risks of breast cancer after diagnostic radiation at a young age. Alcohol consumption increases the risk of breast cancer dose-dependently (Table 1). It has been estimated that 50% of the variance in the rate of alcohol elimination is heritable, which renders gene-environment interactions plausible. One of the biological mechanisms may involve folic acid, suggested by findings that folic acid intake mitigates the excess risk of breast cancer due to alcohol intake.
The examples of interaction between alcohol intake and folic acid, and use of hormone replacement therapy and overweight illustrate that through these interaction analyses common biological pathways may be elucidated. Similarly, gene-environment interactions are likely to improve our understanding of the underlying biological mechanisms of breast cancer.
Ovarian cancer. Similarly to breast cancer, established risk factors for ovarian cancer which increase the risk for disease include reproductive variables such as late age at menopause and infertility and family history of breast and/or ovarian cancer (8). Women who use HRT are at an increased risk of both incident and fatal ovarian cancer (9). Use of oral contraceptives confers long-term protection against ovarian cancer. Parity, pregnancy, lactation, tubal ligation, and hysterectomy are also established protective factors. Further suspected risk factors are obesity, tobacco smoke, radiation exposure, psychotropic medication, high-level physical activity (3). Furthermore, a prior history of pelvic inflammatory disease, polycystic ovary syndrome, and endometriosis have been associated with an increased risk for ovarian cancer, the latter especially for endometrioid and clear cell histologies.
Migrant studies have shown that Japanese migrants to the US markedly increased their risk of ovarian cancer, suggesting that modifiable risk factors affect the risk within a relatively short period of time. Parity is a well-established protective risk factor and known to decrease in migrants (Table 1). Breastfeeding is found to be protective as well, although no duration-response relationship exists. It has been suggested that the first postpartum period of breastfeeding may be most protective, because suppression of ovulation is greatest during this period. Use of oral contraceptives has a strongly protective effect, and risk is further decreased with longer durations of use. The protection persists for at least a decade after stopping of use. For BRCA1/2 carriers findings are inconsistent. Though most studies report a protective effect, this is not found in all studies. In order to explain the protective effect of oral contraceptives, it has been suggested that the incessant ruptures of the ovary, caused by ovulations, may increase the risk of ovarian cancer. Another theory stresses the role of gonadotropins. Hormone replacement therapy increases the risk of ovarian cancer, and even more so with longer durations of use. Tubal ligation is clearly protective. Possible biological mechanisms include an altered ovulation pattern, obstruction for carcinogens to reach the ovaries and a lower exposure to hormones through reduced blood flow to the ovaries. Overweight seems to increase the risk of ovarian cancer. Some studies suggest that the association is stronger among premenopausal women, but clear explanations of this association are lacking.Prostate cancer. The aetiology of prostate cancer is complex and little is known about the molecular processes involved in initiation and progression of prostate cancer. Growth factors such as IGF (10), the vitamin D hormonal axis (11) as well as inflammatory processes (12) appear to play a role in the development of prostate cancer.
The individual prostate cancer risk depends on the interplay of genetic, dietary, and lifestyle factors. Established risk factors are older age, family history of prostate cancer, and African-American ethnicity. Steroid hormones are likely to play a role since androgens are involved in the development and maintenance of the prostate gland. Body height has been shown to be a risk factor of prostate cancer in several populations (11). Attained height reflects the metabolism of steroid hormones, growth hormone and IGF-1 during puberty, which may influence the growth of the prostate gland. Obesity was suggested to play a role in prostate cancer via the effect on sex hormones such as oestrogen and testosterone. However, the association between BMI as a marker of obesity and prostate cancer is inconclusive. Modifiable risk factors such as diet, smoking, and physical activity may influence the risk of prostate cancer through effects on molecular processes involved in carcinogenesis and/or progression, or inflammatory processes including oxidative stress (3).
The most well-established risk factors for prostate cancer are age, race and family history. Other factors, such as hormones, diet, anthropometric measurement, sexual behaviour etc have also been strongly suggested. Anthropometric measurements such as body size, obesity and height, have been shown to be positively associated with prostate cancer in many studies. Meta analysis has shown that height, rather than weight, has a more consistent relationship to prostate cancer. Results on body mass index (BMI) are show greater variation across studies, due to different case/control inclusion criteria between the studies and possibly because the index itself does not reflect the distribution or composition of body fat and lean body mass.
Current data suggest that men who become sexually active at an earlier age, men who have more sexual partner, higher frequency of sexual activity have an increased risk of prostate cancer. It is thought that excessive hormonal stimulation may contribute the development of the cancer, but the exact mechanism is still unclear since human sexual behaviours are complex, and frequency of sexual activity may be affected by hormone levels, as well as other underlying diseases or psychological factors. History of sexual transmitted disease has also shown to be associated with prostate cancer. Meta-analysis show that the population attributable risk is of the order of 6-8% of all prostate cancers. There is inconsistency in the risk associated with the individual sexual transmitted diseases, so although infections may play a role in the development of prostate cancer, the mechanism(s) and most active agents are not fully established.
In conclusion strongly suspected risk like anthropometric measurements, sexual activity, sexually transmitted diseases and other factors that become confirmed over the timescale of the project will be further examined.
Genetic variation and risk of breast, ovarian and prostate cancer. Twin and family studies have demonstrated that breast, ovarian and prostate cancers also have an important inherited component. The most important known genes, BRCA1 and BRCA2, confer high lifetime risks of breast and ovarian cancer, and increased risks of prostate cancer. Genetic testing for these genes in women with a strong family history of breast or ovarian cancer is now implemented in most European countries. However, mutations in these genes are rare, and account for less that 5% of breast, ovarian and prostate cancers. Genetic linkage studies in families have indicated that further important high risk genes are unlikely to be found. This has led to the hypothesis that susceptibility to these cancers is polygenic, that is driven by many different genetic variants. Each of these variants confers a modest increase in risk, but these risks combine, together with other risk factors, to define the overall disease risk.
Direct evidence for the polygenic basis to these diseases is provided by the identification of some of the genetic loci responsible. The identification of such loci requires genotyping of large numbers of cancer cases and controls, and until recently this was only possible for limited numbers of candidate genes. By this process mutations in the DNA repair genes ATM, CHEK2, BRIP1 and PALB2 have been shown to be associated with breast cancer. In addition, through BCAC we have identified CASP8 D302H as a protective breast cancer allele.
Recent technological advances have extended association studies to genome-wide scans. These scans allow hundreds of thousands of single nucleotide polymorphisms (SNPs) to be typed simultaneously. Genome wide scans have allowed associations to be identified empirically without prior knowledge of location or function. We have completed the first such study in breast cancer, which identified five novel breast cancer loci. Similar studies in prostate cancer have identified four prostate cancer loci. The loci identified to date explain ~25% of the genetic variation in breast cancer risk, and ~9% of the variation in prostate cancer risk (Table 2).
Current studies indicate clearly that no common variants conferring large risks of disease (relative risks >2) are likely to exist. They also indicate that the susceptibility loci do not reside in previously suspected relevant pathways (e.g. hormone metabolism or DNA repair), which underlines the likely ineffectiveness of the candidate gene approach as a strategy for association studies. They also suggest strongly that many additional loci for these diseases exist, and that studies of the size of the consortia are sufficient to identify them reliably (while smaller studies could not). For example, the breast cancer locus on 8q (rs13281615) was reliably identified, despite the power to detect it being only ~3%. We estimate that the strategy proposed involving the follow-up of much larger numbers of SNPs, will have sufficient power to detect most such loci.
|rs Number
|Minor allele frequency
|Per allele relative risk
|Familial risk explained (%)
|1 in 1700
|1 in 1500
|1 in 5000
|1 in 25000
|1 in 1700
|1 in 1500
|MMR genes
|1 in 5000
|1 in 1500
Gene – environment interaction. An important aim of the current proposal is to evaluate systematically the combined effects of genetic and lifestyle/hormonal risk factors for these cancers. This is based on the hypothesis that in individuals who are genetically susceptible to these cancers, the effects of certain environmental/ lifestyle risk factors may be different. So far, the effects of environmental/lifestyle factors on cancer risks according to genetic make-up have mostly been examined in relatively small studies that focused on specific candidate loci, and thus had insufficient statistical power to examine gene-environment interactions. Lack of statistical power in studies conducted so far means, on the one hand, that relevant interactions may have gone undetected, while on the other hand too much attention may have been directed to false-positive findings that could not be replicated in subsequent studies. A serious problem in studies assessing gene-environment interaction is that a great many associations are tested. Even if the analysis is restricted to a limited number of genes and established environmental/lifestyle risk factors, this results in hundreds of associations to be tested. For instance, for breast cancer there are at least 10 established risk factors, each of which can be defined in various ways according to intensity or duration of exposure (e.g., alcohol use consists of various components, such as: ever/never, number of glasses consumed per day recently, or 10 years before diagnosis, type of alcoholic beverage). This implies that the chances of false positive results are high, in particular when taking into account that some investigators (and journals) are tempted to only push these positive associations. To solve this problem, huge studies are needed in order to systematically assess gene-environment interactions, while employing conservative strategies for statistical significance testing. Moreover, powerful analytical tools will be required to model the complex interaction of multiple genes and risk factors. The large consortia participating in this grant will enable such a systematic approach. The consortia also constitute an excellent platform to broaden the genetic profile that may be relevant, and to provide a powerful dataset to increase our insight into the effects of established risk factors in genetically susceptible subgroups. The identification of significant interactions between genetic loci and lifestyle/hormonal risk factors will strengthen the evidence that these risk factors are causally related to disease and will also improve the understanding of the biological mechanisms involved.
In statistical terms, an interaction between risk factors is defined as a departure for a specific model, often a departure from multiplicativity. Under this model, a genetic factor and a lifestyle factor that combine multiplicatively would not have no interaction, and interaction is only present when the joint effect of the genetic factor and the lifestyle factor of interest is stronger (or weaker) than the product of the two effects. This differs from the usual biological interpretation, in which two factors combining multiplicatively would be regarded as an interaction or synergy. From the point of view of individual risk prediction and public health, what matters is not so much the evidence for any particular definition of interaction, but obtaining reliable estimates of combined effects of these risk factors. Even if there is no statistical interaction, the combined effects will still be important. For example, for a SNP associated with a relative risk of 1.5 and a risk factor (for example nulliparity) associated with a relative risk of 2, the variation in risk between the highest and lowest risk individuals will be 1.5 x 2 = 3 fold. Much bigger differences in risk will be generated once all the genetic and lifestyle risk factors are considered.
Risk models format. In order to provide individual estimates of disease risk, the effects of individual risk factors need to be incorporated into a risk model. Existing models based on lifestyle risks (e.g. the Gail model) have limited predictive value. Members of the consortium (UCAM) have previously developed a genetic risk model for breast and ovarian cancer (Boadicea) that can account for the effects of BRCA1, BRCA2 and other genes, and can be applied to women with any family history. This model has been implemented online (http://www.srl.cam.ac.uk/genepi/boadicea/boadicea_home.html), making it available both to the medical community and to patients and their families. A major objective of this proposal will be to build on this model to incorporate the effects of the established risk factors, newly identified loci and their interactions, and to build a comparable model for prostate cancer.
Tumour subtyping. In clinical practice cancers are stratified using clinical staging and morphological markers of aggressiveness, which are important predictors of treatment response and outcome. However, it is recognised that there is considerable heterogeneity in the behaviour of tumours, beyond the traditional prognostic markers. Methods for sub-classifying tumours have become more sophisticated with the use of expression microarrays and tissue microarrays. Such subclassification is important because subtypes can reflect differences in aetiology and has the potential to better predict prognosis and response to therapy. Already, such evidence has emerged. For example, BRCA1 mutations predispose to a specific subtype of breast cancer (oestrogen receptor negative and of basal subtype), while recent evidence suggests that several of the novel breast cancer loci predispose to specific subtypes of the disease.
By taking subtypes of cancer into account when relating cancer risk to genetic factors and gene environment interactions, specific aetiologic pathways may be picked up, in which the effects of environmental/lifestyle risk factors may prove to be more clearly apparent. Thus, this approach may substantially increase the chance of finding relevant gene-environment interactions. In a larger perspective, detailed knowledge of the carcinogenic process is needed to identify novel therapeutics. In addition, genetic and lifestyle risk factors may influence disease outcome. The current proposal will also allow a comprehensive evaluation of the associations between genetic loci, lifestyle/hormonal risk factors, and tumour subtypes, with disease outcome. This is important since it will allow prediction of of the risks of a fatal cancer, which is more relevant to the ultimate aim of reducing disease mortality.
Implications of COGS. The most practical application of this work is to define more precisely the individual risk of disease. We have previously shown that, under the polygenic model, the predictive value of genetic testing can be substantial. For example, for breast cancer, we have estimated that approximately 50% of the disease will occur in the 12% of the population at highest risk, implying that preventive programmes targeted on those at highest risk would have a substantial population impact. One of the aims of this proposal will be to evaluate the public health implications of the risk models we develop.
COGS will identify individuals with a testable polygenic profile that are at substantially increased risk of disease and determine whether specific lifestyles have a greater impact in this genetic subgroup. As a consequence, genetic counsellors will be able to provide more specific risk information to the counselee. Moreover, such evidence may increase general awareness of current knowledge on tumour aetiology, systematically informing a motivated group within the general population that seeks advice to lower their cancer risk.
Risk classification may have other important implications for screening and prevention. For example, standard screening for breast cancer is by X-ray mammography and commences at age 50 in most EU countries. Recent studies have shown that screening by magnetic resonance imaging (MRI) is a more sensitive technique (13), but it is expensive and has low specificity. MRI is currently recommended for women that are carriers of BRCA1 or BRCA2 mutations, but could be extended more generally to other women at high risk if such women could be reliably identified. For prostate cancer, screening by prostate specific antigen (PSA) is widespread in many countries. An ongoing international study, IMPACT (http://www.impact-study.co.uk/), is investigating intensive PSA screening in male BRCA1 and BRCA2 carriers and a related EU funded project, AIDIT (Advancing International Co-operation and Developing Infrastructure for Targeted Screening of Prostate Cancer in Men with Genetic Predisposition; http://europabio.euproject.eu/index.php/kb_3130/io_492/io.html) expanded IMPACT into Associated Candidate countries. If successful, targeted screening could be extended to other high risk individuals. The AIDIT project is an example of how previously funded EU contracts expands into other consortia and thus adds value to money already spent. Many of the groups in PRACTICAL, came into PRACTICAL via AIDIT. We now hope that we can take yet another step on the added value path by introducing COGS.
More active prevention strategies are also important. Randomised trails have shown that giving women tamoxifen or other anti-oestrogenic agents can reduce breast cancer risk (14). However, the side effects, such as an increased risk of endometrial cancer (15), are substantial, and it will be important to define for which individuals such chemoprevention is appropriate. Finally, for individuals at the highest risk, prophylactic surgery may be appropriate. For example, according to the guidelines of the UK National Institute for Clinical Excellence (http://guidance.nice.org.uk/cg41) prophylactic mastectomy would generally be offered to women with a >30% lifetime risk of breast cancer. Results from COGS will define more precisely which individuals fall into such a high risk category for each cancer.
The identification of associations between genotype, disease subtype and clinical outcome will also be important. This allows prediction of likely outcome in terms of disease-free and overall survival, of critical importance to counselling and prevention strategies. These results will have a vast implication for counselling of high-risk individuals.
Finally, the identification of significant interactions between genetic loci and lifestyle risk factors will strengthen the evidence that the risk factors are causally related to disease and improve the understanding of the mechanisms through which the risk factors cause disease.


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Nobody Chair
Komplot Design for HAY
Komplot and HAY's Nobody Chair was an industrial sensation when it was launched in 2007. A stackable chair moulded in a single piece from one hundred percent recyclable plastic converted into felt had never been done before. Nobody is soft, comfortable and versatile with no hard edges or loose parts. The lightweight chair has the additional advantage of making no noise or scratches when pulled across the floor, and is easy to pick up and move around. Its elegant curved silhouette married with innovative design and sustainable approach makes Nobody a timeless classic that is suitable for a wide variety of private and public settings.
This product is stackable (up to 4 pcs.).
22.83" W x 30.71" D x 27.95" H
PET felt, Polymer Fibre
Recycled Material from Plastic Bottles
Felt in 2 Layers
Design Public is an authorized USA dealer for all HAY products.
Founded in 2002, HAY has established itself as one of the up-and-coming furniture design firms in Denmark...
Designed by Komplot Design
Komplot Design's multidisciplinary activities within product, furniture and graphic design, from tractor to office furniture systems and to brochures and...
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Property brokered by
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Presented By:
Jeff Davis
(337) 344-4236
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Jeff Davis
(337) 344-4236
Email Agent
Property DetailsLarge three bedroom two bath new construction home by Mitch Higginbotham Construction in Sabal Palms. 1983 Sq ft Living area with open split floorplan and separate Study/office. Large open kitchen, dining, living area with 11 ft ceilings and fireplace. Kitchen outfitted with walk in pantry, gas cooktop, all stainless appliances, and granite counter tops through-out. Exposed beams with dry-brushed ceiling with lighting above kitchen area. Large master suite with Shiplap accent wall in bedroom, bath area with double vanities, 6ft whirlpool tub, separate custom shower, and walk-in closet. Outside covered patio area with fireplace.
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Additional Property InformationThis single family listing located at 102 Sago Palm Way, Youngsville, LA boasts three bedrooms and two bathrooms. A new traditional style property, it is currently selling at $319,000.
This property is presented by Jeff Davis of Keaty Real Estate headquartered in Louisiana.


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Fairfax, VAUSA
Hometown: Westport
January 15, 2014
Maybe not high school but definitely college!
John Adams
Revolutionary War
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Love learning about the past. Its interesting and intriguing - better than any fictional drama! Recently moved back to the area from CT after 13 years where I was in a non-fiction book club. We read a vast array of history and current affairs.
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The company behind Headley Grange and Four Kicks is making a new cigar with the Garcias of Nicaragua, makers of the award-winning Flor de las Antillas and a host of other cigar brands. Crowned Heads LLC and My Father Cigars S.A. are going to release a cigar in May called Las Calaveras Edición Limitada 2014. It will be the first Nicaraguan smoke for Crowned Heads.
Themed around traditional Mexican Day of the Dead imagery, Las Calaveras is meant to pay respects for lost loved ones.
"Calaveras will be an annual release that is a respectful homage to those who have passed away in the year before," Crowned Heads co-founder Jon Huber told Cigar Aficionado. "Rather than a symbol of sadness or death, it's intended to be a celebration of their lives and remembrances."
Las Calaveras EL 2014 will come in three sizes: a 5 inch by 50 ring robusto, a 6 by 52 toro and a 7 by 54 Churchill. They'll be packaged in black, slide-lid boxes of 24 (with three rows of eight cigars) adorned with a festive skull logo. Only 1,000 boxes of each size are slated for production.
For much more on this story, see today's Cigar Insider.
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I agree with some blogs seemingly taking news pieces and not giving credit if the story was broke earlier from CA or another publication. I guess since they're not legitimate news sources or publications they can do this. I do think/hope most know where to get their reliable information.
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Question: A recession may reflect declines in aggregate demand aggregate supply
A recession may reflect declines in aggregate demand, aggregate supply, or both. Are swings in consumer sentiment characteristic of recessions? Plot a measure of sentiment (FRED code: UMCSENT) and discuss its evolution during the recessions since 1980? Explain why consumer sentiment is an important example of an aggregate demand shock.
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Answer to relevant QuestionsHow often is negative supply shocks associated with recessions? Plot on a quarterly basis since 1971 the real price of oil measured as the ratio of the nominal price of oil (FRED code: OILPRICE) to the U.S. Consumer Price ...*According to real business cycle theory, can monetary policy affect equilibrium output in either the short run or the long run? *Suppose a natural disaster reduces the productive capacity of the economy. How would the equilibrium long-run real interest rate be affected? Assuming the central bank maintains its existing inflation target, illustrate the ...*How could you use the aggregate demand-aggregate supply (AD/AS) framework to explain the impact of the financial crisis of 2007-2009 on inflation and output in the economy? The government decides to place limits on the interest rates banks can pay their depositors. Seeing that alternative investments pay higher interest rates, depositors withdraw their funds from banks and place them in bonds. ...
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text:
Adventures of Milo and Otis (Blu-ray)
Masanori Hata
Director: Masanori Hata G
Milo is one lucky cat. He's got nine lives and a best friend.
LOW STOCK: Only 3 copies left
|$16.75 Limited Time Only
|List Price:
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|$3.24 (16% Off)
Available: Usually ships in 1-3 business days
Format: Blu-ray (2 Discs)
sku: FYYW
Brand New
Also released as:
Blu-ray Disc Features:
- Number of Discs: 2
- Rated: G
- Run Time: 1 hours, 16 minutes
- Video: Color
- Released: January 24, 2012
- Originally Released: 1989
- Label: Sony Pictures
- Encoding: Region 1 (USA & Canada)
- Aspect Ratio: Widescreen - 1.85
- Audio:
- Dolby Digital 2.0 Stereo - English, Spanish
- Dolby Digital 5.1 - English, Spanish
- DTS HD Master Audio - English, Spanish
- Subtitles - English, French, Spanish
Performers, Cast and Crew:
|Dudley Moore
|Directed by
|Masanori Hata
|Narrated by
|Dudley Moore
Entertainment Reviews:
New York Times - 08/25/1989
"...The wonder of Hata's anthropomorphic fairy tale...is that it is cast with real animals who seem to share deep affection. And the mixture of realism and fantasy lends this children's film a poignancy..."
"...The wonder of Hata's anthropomorphic fairy tale...is that it is cast with real animals who seem to share deep affection. And the mixture of realism and fantasy lends this children's film a poignancy..."
Los Angeles Times - 08/25/1989
"...There's something delightfully pure and fresh about the children's film THE ADVENTURES OF MILO & OTIS....It generates the blissfully dry sense of wonder the best children's books or movies often do..."
"...There's something delightfully pure and fresh about the children's film THE ADVENTURES OF MILO & OTIS....It generates the blissfully dry sense of wonder the best children's books or movies often do..."
Product Description:
Milo, the curious kitten and Otis, the pug-nosed pup journey to a dazzling world of natural splendor when Milo accidentally sets sail down the backyard creek in a box and Otis follows behind along the shore. Narrated by Dudley Moore.
Plot Synopsis:
Farm cat Milo and his best friend Otis the dog try to make their way home after Milo is accidentally swept away by the rampaging river.
Production Notes:
- The original Japanese film, "Koneko Monogatari" ("The Adventures of Chatran"), ran 90 minutes and concerned the adventures of a cat, Chatran, who wanders periodically from his farm home and adventures into the wilds of Hokkaido.
Director Masanori Hata and associate director Kon Ichikawa edited the film together from 400,000 feet of footage. They used several different cats, from a kitten to a fully grown adult, to give the illusion of the progression of time over several seasons.
Hata is a zoologist and novelist (under the pen name Mutsugoro) and runs an animal farm near Hokkaido.
Ichikawa is himself a well-known director. His most famous films are "An Actor's Revenge" (1962) and "The Burmese Harp" (1956).
Following the film's success at the 1986 Cannes Film festival, Variety wrote that,"'The Adventures of Chatran' is a stunning achievement... [Sakamoto] has come up with strongly evocative interpolations of a basic melodic base that once heard is hard to forget... Hata, as the pic makes obvious, has an unusually strong rapport with animals. He places his charges in situations required by the pic's general structure, and then captures the unpredictable results in eye-popping ways... while maintaining a sense of dignity for his charges."
"Koneko Monogatari" was the second highest-grossing film ever in Japan, behind "E.T."
The American version was recut and runs 76 minutes long and has a different story line.
- Shot in Eastmancolor and Panavision.
- Estimated budget $8 million.
- Released in USA August 25, 1989. Released on video January 31, 1990.
- Reviewed in the New York Times August 25, 1989.
- Rated BBFC U by the British Board of Film Censors
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text:
Recently Rajasekhar has come up with a song 'NaMO' to make voters go and exercise their vote towards the BJP PM candidate. That particular song was composed by music director Acchu. At the same time, Jeevitha claimed on stage that her daughter Sivani has penned lyrics for the song. Can you imagine an English medium student studying in Hyderabad writing Telugu lyrics like 'O Kanniru tudichey karunapadam, Ee Namo Namonamantram'. Anyway, truth is not far away as it is revealed that a music composer turned song writer Vengi has written this song.
Talk is that Vengi got surprised as he doesn't even know that the particular song is already released on internet. Though the lyricist tried to contact Jeevitha as they have announced that the couple's daughter has written the song, all those efforts turned futile. What will Rajasekhar say about this now? Will he publicly admit to his mistake or cheating, whatever? Giving lectures about others is easy task!


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If Anna and Elsa were younger and went to the Arendelle High School prom, their dresses might look like these Quinceañera gowns. They're poufy and sparkly, and I would happily wear one. I especially love all the ruffles on the purple and blue dress inspired by Anna. The Frozen dresses are part of the Disney Royal Ball line for spring 2015 and are priced at $530 and up.
See individual photos after the break.
(via Stitch Kingdom)


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I have a 10 year old male cat, who has a urinary tract infection right now. He pees just a little amount, quite often, and all around the house. He's on antibiotics for the next two weeks, but when he's better, I'm worried that he's going to smell where he peed before, and pee there again. Any tips?
Also, I heard if you let your cat outside once in a while, the inappropriate urination seems to stop. I'm worried, because his front paws are declawed, that another cat will attack him, and he won't be able to defend himself. Will this happen?
Hope your cat is better soon. I would clean the spots with hydrogen peroxide. I put it in a spray bottle and spray the spot then use water in a bucket with a rag wet the area down and use a dry rag to get the rest of the water up. The peroxide won't ruin carpet etc., but just to be on the safe side I would try in first in an area that you can't see.
I would not let your cat out if he is declawed. The vet will let you know what to be feeding your cat if he is prone to urinary infection. I think if you feed dry food it should be low ash content. I feed canned and dry to my cats.
Liz (08/04/2004)
By Liz acraftycat
I hope your cat is doing better. I have had male cats with urinary tract infections, after they were better they did not go anywhere, but in their box. There are cat foods out there dry and wet, they are normally called special diet, that's what I used and haven't had a problem since. Good luck.
Evie (08/04/2004)
By EVIE
I have always used plain white vinegar on such "accidents". Just wet a rag and dab the spot so that it is pretty wet, then let it dry (the vinegar smell goes away quickly). Hydrogen peroxide can be used to bleach out stains on fabric, so I'd be leery of using it on carpet.
I buy the "special diet" food for our "little old man" cat (he is 15 now and still enjoying life).
Hope your fella feels better soon. (08/09/2004)
By Becki in Indiana
You should not let a cat that has been declawed outside ever. There is no way for him to defend himself. What's your 1st instinct when approached with danger head on? You put up your hands. Same with him except it would be front paws.
Buy the spray from Walmart in the pet department. It has special enzymes in it that destroy the bacteria that causes the urine odor to remain. It is safe, cheap and it works. (08/09/2004)
By Denise
Do put your cat on the special diet food. It will help with the urinary tract infections and he'll also lose weight on it. The special diet foods are more easily digestible so you'll have less mess to clean in the litterbox.
To locate the spots where he's peed here and there, get a black light lightbulb in a lamp and shine it around your home. Wherever he's peed will glow under the light and you'll know where to clean. (08/10/2004)
By certified
Your best bet is to talk with a vet about the problem. I have a (spayed) female cat who developed a urinary tract infection a good many years ago. The vet put her on a special diet (only available at vet. clinics) and told us not to give her anything with fish or seafood, even flavored. That fixed her up, but the food was expensive and she had a problem with hairballs as well. I read the ingredients on the food bag, found a premium "hairball formula" food in the store that seemed right and tried it. This has saved me some money, she still has no U.T. infections, and her hairballs aren't as bad. Oh, and she likes this a lot better too.
Good luck. (08/12/2004)
By Warren D. L.
I have a male neutered kitten currently with a UTI the vet put him on amoxicillin. Told me to get Uri-ease from Petsmart for him and he eats those really well. Use non clay litter which I haven't ever used anyways and scoop his boxes at least 5 times a day. The vet also told me to feed him wet cat food and mix 1-2 tablespoons of 100% cranberry juice with his wet food each time I give it to him until he's over the UTI. Also, to feed him Blue Buffalo cat food which is natural and also has cranberry in the food among other minerals and vitamins. I do not know if this is going to work yet, but sounds similar to what would be done if I had a UTI so sounds right to me. Hope this might help someone else. (09/05/2009)
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text: this wedding was one of my all time favorites. these are just the day of "bridals" that we did in san francisco between the ceremony and reception. i had so many favorites i had to split them up into two posts (the full wedding later to come). kristina & andres are an absolutely amazing couple, i am so glad i was able to go to california and spend the day with them!


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When people ask us which smartphone is best for their needs, we generally struggle to answer. That's because the market is flooded with so many smartphones and price ranges to suit those different types of handsets.
Recommended: Samsung Galaxy S6: 10 New Rumours You Should Know
Buying a new smartphone isn't simple anymore. After all, a smartphone is like a full blown computer. There are so many factors to consider including display size, performance, camera, and more. But there are some common factors you should consider, regardless of what kind of smartphone you are searching for.
Recommended:8 Apple Products We Expect to Launch in 2015
Check out our list of 10 things that you need to consider before picking a smartphone of your choice.
Display Size and Form Factor
10 Quick Tips to Consider Before Picking a Smartphone
If you are looking to buy a new smartphone, one should make sure you get a screen that is comfortable to glance at. Big screen smartphones are popular in India, as they give a lot of more real estate for watching movies and playing games. For instance, the 5.7-inch Samsung Galaxy Note 4 is honestly a great device for playing games.
Meanwhile, a smaller display size should be just enough for your daily needs. Say, an iPhone 5S, for instance, is a compact smartphone without compromising on features.
Operating System (OS)
10 Quick Tips to Consider Before Picking a Smartphone
There are three main operating systems (OS) to choose from. Google's Android remains one of the most popular mobile OS of all time. Compare to iOS and Windows, there are so many hardware options from several top-notch manufacturers. Plus, the Google Play app store offers more local apps than any other rival platform.
Apple's iOS is a fluid OS but it's restricted to the iPhone. Windows is yet another option in the handset market. The platform is fairly new, but it definitely offers the best native software experience, thanks to the built-in MS Office.
10 Quick Tips to Consider Before Picking a Smartphone
A handset's processor is usually considered the brain of the device. A fast one will obviously enable you unlock your device to the fullest. The most powerful state-of-the-art chip for Android Qualcomm's Snapdragon 801. This CPU offers unmatched multitasking and high powered graphics.
The Snapdragon 410 is found on cheaper handsets.
Interestingly, the chipset also offers 4G LTE connectivity. Other than Qualcomm's Snapdragon SoC, you'll find the MediaTek processor, which offers fairly decent performance. For iOS, Apple A8 chipset inside the iPhone 6 offers 64-bit power.
10 Quick Tips to Consider Before Picking a Smartphone
Today's high-end devices offer 3GB to 4GB of RAM, while lower-end to midrange phones get away with 1 GB to 2 GB. If you consider yourself a heavy user, then probably consider a smartphone with at least 2GB of RAM.
Display Resolution
10 Quick Tips to Consider Before Picking a Smartphone
Next, look at the screen resolution. The display size of the smartphone definitely matters a lot. As of now, 2K screens (2560 x 1440 pixels) are the sharpest you'll find on smartphones. However, we've seen smartphones with 720p displays, such as the Xiaomi Redmi Note 4G, are as good as any other premium device.
Storage and Expansion
10 Quick Tips to Consider Before Picking a Smartphone
Storage is an important factor when you consider a new smartphone. The majority of bargain-priced smartphone come with 8GB of native storage. If money is no object and you want the bigger storage available then consider buying a smartphone with either 16 or 32GB of on-board storage.
The idea of expandable storage is also gaining popularity. So it would better to choose a smartphone that offers an expandable storage.
10 Quick Tips to Consider Before Picking a Smartphone
The quality of both the camera sensor and the images is important. Even though the iPhone 6 has an 8MP camera sensor, but its new sensor allow for bigger pixels, incredible shots. At the same time, front facing cameras are becoming popular.
10 Quick Tips to Consider Before Picking a Smartphone
Determine how long the battery is expected to last under normal use. The average phone lasts 7 hours. Always consider a smartphone with bigger battery life. In general, look for 2,800 mAh or more
10 Quick Tips to Consider Before Picking a Smartphone
Look for a smartphone with an array of connectivity options. They are very important. Smartphones need to have access to wireless communication, including Wi-Fi connectivity, 3G and 4G. Make sure your next smartphone offers 4G connectivity.


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I'm real bad at telling if a guy is interested in me. Here are some of the things my guy friend does: walks super close to me when there's a tone of space (like glued to my arm), looks at my lips, tells me "I'm still single ;)", always makes sure I'm healthy (now he's more caring than usual), uses more emojis than usual, tells me that I'm amazing, leans when I'm talking and maintains eye contact the entire time, his friends giggle at him when I'm around, looks at me up and down, always touches my arm gently, and he once said that he's going to wait a year to transfer to a university, then immediately asked when I was getting out, and I told him in a year... he knows that already though. So, is he interested in me?
Most Helpful Guy
Most Helpful Girl
I would say those are all pretty good signs of a yes, he does.11|00|0


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I know looks are really important to men so would you ever settle for an average looking girl? Or would you have to be desperate to do that?
Most Helpful Guy
Of course, as long as her personality is beautiful. Believe or not, there are men out there that aren't all about looks. :)42|20|0
What is average in your opinion?
- Show AllShow Less
Well first of all, every guy is different. We don't all go for the hottest girl in the room. Some guys will be attracted to the 'average' girl. Or possibly even the not so good looking girl. Every guy is different. Now I'm older now so looks don't matter as much. It's the personality. My definition of an average looking girl would be someone who looks good without makeup. Natural looking. Pretty much the typical girl in today's society who isn't all that high-maintenance. Make sense?
@QA agreed with jmowen


text: Post your ratings, and thoughts in this thread. Hardcore Justice recap: - Bram defeated Abyss - EC3/Rhino brawl - Samoa Joe defeated Low Ki - Mr.Anderson defeated Samuel Shaw - Gail Kim defeated Angelina Love (personal MOTN) - Bobby Roode and Eric Young escaped the cage at the same time. Winner to be determined next week?


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the attribution of human characteristics or behavior to a god, animal, or object
derives from its verb form anthropomorphize, itself derived from the
Greek ánthrōpos (ἄνθρωπος,
"human") and morphē (μορφή,
"form"). It is first attested in 1753, originally in
reference to the heresy of applying a human form to the Christian
God. [from the wikipedia entry]
Yet, isn't the very reach in defining something, putting into words what the human's perception of what something "is" yet another form of anthropomorphism?
It seems the human being, by default, puts all of its ideas firstly through the mill of anthropomorphism.
It is the effort of looking at something objectively and not 'as' a human being ( if this is actually possible ) that 'may' somehow grant the observing human being a clearer picture of the world and its contents, as it is, and not as an extension of the human perception.
The video is an example of 'seeing' birds perching on wires as a piece of sheet music.
The man who beautifully put music to what he saw had previously learned to 'read' music as written on lines.
To a person not having a clue as to what sheet music is, they may see perhaps a different pattern, or something else, beyond the image of those birds on the lines... yet most likely attributing what they see according to their perception and according to their human experience(s).
Read about anthropological linguistics for further insight.
Herein is the point of this observational blog post:
The definition of this term anthropomorphism includes human beings projecting their concept of 'god' / God as, and as we've already seen, through their human perception ( according to what the human understands ).
Yet, is this actually a true statement considering all things?
As with many attempts to answer a provocative question, the answer is paradoxically "yes" and "no".
Then God said, "Let us make mankind in our image, in our likeness, so that they may rule over the fish in the sea and the birds in the sky, over the livestock and all the wild animals, and over all the creatures that move along the ground."
So God created mankind in His own image,
in the image of God He created them;
male and female He created them.
- Genesis 1: 26-27This seems to read that mankind was made in God's image, not the other way around as the man-made and man-perceived definition suggests.
The Son is the image of the invisible God, the firstborn over all creation. For in Him all things were created: things in heaven and on earth, visible and invisible, whether thrones or powers or rulers or authorities; all things have been created through Him and for Him. He is before all things, and in Him all things hold together. And He is the head of the body, the church; He is the beginning and the firstborn from among the dead, so that in everything He might have the supremacy. For God was pleased to have all His fullness dwell in Him, and through Him to reconcile to Himself all things, whether things on earth or things in heaven, by making peace through His blood, shed on the cross.
- Colossians 1: 15-20It seems that the vastness of 'what' and 'who' God is goes beyond the visible, yet we've been granted a glimpse in Yeshua Christ, a glimpse as to what that 'image' looks like... complimenting the passage in Genesis.
No one has ever seen God, but the One and only Son, who is Himself God and is in closest relationship with the Father, has made Him known.
- John 1: 18And this glimpse, this experience the earliest believers had when seeing, touching, hearing and walking with the One from Above; the anthropomorphism was not in vain as skeptics may criticize.
It is quite striking how the disciple Thomas finally came to faith:
A week later His disciples were in the house again, and Thomas was with them. Though the doors were locked, Yeshua came and stood among them and said, "Peace be with you!" Then He said to Thomas, "Put your finger here; see My hands. Reach out your hand and put it into My side. Stop doubting and believe."
Thomas said to Him, "My Lord and my God!"
Then Yeshua told him, "Because you have seen Me, you have believed; blessed are those who have not seen and yet have believed."
- John 20: 26-29We who Today believe are quite blessed to 'see' without having seen the image... the very image and likeness we've been created and made to reflect.
Praise His Holy Name!


text:
The power to copy another power by a telepathic link. Combination of Telepathy and Power Replication. Not to be confused with Empathic Mimicry.
Also Called
- Psyche Mimicry
- Psychic Power Replication/Mimicry/Copying
The user can copy another power from another person via a telepathic link. So long as the link exists, the user can use the powers of others.
- Users of Psychic Shield (highly resistant) and Psychic Immunity (impervious).
- If the mind link is severed, the user will lose the replicated power.
- May be temporary.
- Unable to copy from those with Power Mimicry Immunity.
Known Users
- Zachary (Charmed)
- Emma Frost (Marvel)
- Onslaught (Marvel)