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The beginning of 2015 started off really rough. I will give you the short version of the story but if you want to read about it in more detail, you can read about it here
Last October we decided to put our house up for sale because my husband's job was going under and his paychecks were bouncing, which made it really hard to pay our bills. We didn't want to fall more into debt because we were already close to $10k in credit card debt. So in November our house was officially on the market and our plan was to move in with his widowed grandpa so we could help take care of him and get rid of debt. December 20th we moved into his grandpa's basement and in January our house finally sold! Life was good. We were chipping away at our debt month by month. Little by little we were getting closer to financial freedom. We started to feel settled into our new lives. We loved living with his grandpa and felt like our family grew to a family of 3 to a family of 4. We were so grateful for his grandpa's generosity and the opportunity to set our finances on the right track.
February rolled around and grandpa caught a cold and like out of nowhere that cold turned into pneumonia and in February we lost him. We were shocked because of how quickly his health declined. At this point we had no idea what our future had in store for us because as far as we had planned, we were going to be living with him for a couple of years to get rid of debt and establish a good solid savings account. From February until July, we had experience so much heartache and felt so lost as to what to do next. It was a very hard time for us.
July is when things began to change for me. July 20th was my 31st birthday and my best friend and I decided to really make our 31st year a great one! We wanted to make this year our greatest year yet, so we wrote down our goals and shared them with each other. We were determined that this year we were going to be our best selves.
After the night I wrote my goals down, things began to change for me. Within that next week, I felt like the Universe was conspiring to make my desires happen.
3 of the goals I had written down were:
1. Get in the best shape of my life
2. Create an extra stream of income that didn't take me away from my family
3. Pay off credit card debt (10k)
That weekend after I wrote my goals down, I reconnected with one of my high school friends who was a Beachbody Coach. She had posted on Instagram how she was looking for new coaches to add to her team. We talked to each other on the phone and she told me about the Beachbody Coaching opportunity. I decided to sign up as a Coach that weekend and started my first Beachbody program (21 Day Fix) + Shakeology. Little did I know what I was getting myself into and how much of a positive impact this would make on my life and the lives of my family and friends around me. I signed up as a Coach because I knew this would help me keep myself accountable to what I wanted to do.
I started 21 Day Fix in July after my birthday and 3 weeks later of learning how to eat clean and healthy and making exercise a routine in my life again, my body began to transform! After I completed the program, I lost a pant size and I lost all of my pregnancy weight and finally toned up my body! I finally had the body I wanted to have for the longest time after having my son but just never committed to making health a priority. Not only did I have a physical transformation but I became more of a confident and happier person. I felt amazing and wanted to share my experience with the world. I became passionate about fitness and health. I became a believer that when you take care of yourself, you live a happier and more fulfilling life. I had more energy to be a better wife, mom, friend, daughter and teacher. My life has truly changed for the better.
The beginning of 2015 was very rocky for us but now I feel like we are only going up from here! 2016 has nothing but amazing possibilities and opportunities for my family and I and I can't wait to see how it all plays out!

subset: commoncrawl


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The median home value in Georgetown, TX is $251,500.
This is
higher than
the county median home value of $228,800.
The national median home value is $185,800.
The average price of homes sold in Georgetown, TX is $251,500.
Approximately 67.33% of Georgetown homes are owned,
compared to 26.98% rented, while
5.69% are vacant.
Georgetown real estate listings include condos, townhomes, and single family homes for sale.
Commercial properties are also available.
If you see a property you're interested in, contact a Georgetown real estate agent to arrange a tour today!
Learn more about Georgetown Real Estate.
Are you a builder, or would you like to build your personal home or investment property in downtown Georgetown? This may be your opportunity to own a piece of property walking distance to Williamson Co. courthouse, Monument Cafe, Georgetown square, lots of downtown shopping, dining and bars.
Are you a builder, or dream of building your home or investment property? This is a great opportunity to own and build in an affordable corner of the downtown area. Walk to Monument Cafe, Williamson Co. facility, Georgetown Library and downtown square, full of shopping, restaurants and bars!
Come see this beautiful 5 acre lot on the Middle Gabriel in west Georgetown. Shady oaks dot limestone outcrops as you look down to the water. Walk out your back door to fish or kayak in your own yard. Only 11 homes will be built in Estancia at completion. Well situated, it is a quick 10 minute drive to Georgetown or 40 minute drive to Austin.
SOAK IN THE BEAUTIFUL SUNRISE AND SUNSETS from this HILLTOP PICTURESQUE HISTORIC RENOVATED PARSONAGE FARMHOUSE; HORSE/AGRICULTURAL PROPERTY with GORGEOUS PANORAMIC ROLLING FARM COUNTRY VIEWS; Original Wood floors in this 4 bdrm or 3 bdrm/office down; Gameroom/Bonus room/Office up w/Half Bath; Cheery Light kitchen w/granite & stainless appliances; 30x40 metal building/garage/workshop; 24x36 wood frame barn; 12x12 enclosed tack room; partially fenced w/Centaur & Advantabrd Flex Fence (3 rail & PVC wrapped)
Private, heavily treed 6.54 ac. lot w/Tilson built home centered on property. Open floor plan w/large great room, wood burning stove & high "tongue & groove" ceilings. Master has separate tub & shower, tons of storage & attic is floored. The center island kitchen opens to dining area. Exterior painted 2017, HVAC replaced 2017. Entertain or relax watching abundant wildlife from front or back patios. Stall w/tack room, workshop & shed located in back & 3 ac. are fenced separately in back. Come see!!
Find your own piece of the country. Wide open views. This 55 acres outside of Georgetown provides you with a blank slate. The property would make for a great gentleman's ranch, horse farm or could be kept in crop rotation.
Beautiful 3.21 lot to build your new home in gated community in Georgetown ISD
Beautiful 3.02 lot in gated community to build your new home. In Georgetown ISD
With a Hill Country view, this beautiful 4 bdr, 2 1/2 ba, stone built house on 8.099 acres is up for grabs!There is grazing land in the front & back of the house that has plenty of grass for animals. The home is in great condition with the kitchen, bathrooms & the flooring in the living room & master just remolded.There are some restrictions for this property.This is a perfect home for someone wanting to be in the country.Itâs 15 minutes away from Georgetown & Leander, & about 40 minutes from Austin.
Looking for a luxurious gentleman's ranch? This 11+ acre tract is private yet provides easy access to everything you need. Located in Georgetown, just off of Ronald Reagan and Williams Drive. Shopping and other amenities within a 10-minute drive. This heavily wooded property includes stunning hill country views in all directions with lots of home site options.
Bring big family! Perfect for B&B or for equine pro to to hold weekend clinics with rooms for attendees to stay. Enormous living room! Holiday size formal dining-beautiful granite kitchen with wood stove alcove accessible from living and kitchen, Vaulted ceilings, lots of light-dedicated office with closet-master suite-whirlpool tub & shower-2 separate bedroom wings-5 stall barn with long covered paddocks & air conditioned tack rm-dressage arena-chicken coop-coastal!The works!
Want to live in the country but be close to everything? This is the place for you! Build your dream home on this gorgeous 10 acre plot! Lots of trees and rolling countryside. Just minutes from everything you could possibly need!
Beautiful wooded 3.96 acre homesite! City water on site, native oaks and woods, builder ready. Great subdivision with reasonable restrictions. Just minutes from I-35 or Ronald Reagan Blvd.
An acre lot in the estate section of Cimarron Hills?! This lot is level, has a beautiful heritage oak tree, a high berm with another clump of nice trees at the back of the lot that will provide privacy. The sun will rise at the back of your future and home and you can enjoy amazing sunsets from a front courtyard or patio. Let your imagination run free while planning to build your next home on this gorgeous estate lot! Don't miss out on this one!
Rare find IN the city limits. 12.894 Acres- part pasture & part heavily treed w/soaring oak trees. Country home in the city duplicated from an old home in Tarrytown in Austin. If ever a house feels like a HOME, this is it. Situated among soaring, soaring oak trees with s deck & a goldfish pond, a greenhouse, a well house, a great in-ground pool w/outdoor kitchen, a guest house, and so much more. Jonah water plus a well for watering. Propane tank on property for gas cooking. Front pasture for your horse!
Approximately 9.432 acres at the NE corner of the intersection of University/SH 29 E and Eastview Drive just as 29 widens and across from Eastview High School - Included in the Georgetown ETJ - Entire property is viewable from 29 and Eastview - Must contact agent to walk property
Unique historic farmhouse built in 1907 on 12.12 acres. This home is brimming with character, including shiplap walls in entry, kitchen, and baths. Spacious living/dining area w/beautiful, original wood floors. Lots of open shelving in the bright, airy kitchen. Office and master bedroom on main level. Master bath includes walk-in shower and pedestal sink. Large deck and above-ground pool in backyard. 3 horse stalls. Property is fenced and gated for privacy. Loads of country charm and gorgeous views.
Create the gentlemanâs ranch of your dreams on this 34-acre lot being cut out of the historic R5 Ranch on the San Gabriel River. Amazing panoramic views, Just 12 miles from Downtown Georgetown. Gently sloping and with a multitude of established trees, this lot has several building sites and generous topography. Community is equestrian friendly! Award winning Georgetown schools just right down the road. All the pieces are here to build your country dream home. NO HOA/restrictions.
LAST AVAILABLE LOT! Wilderness Estates is a great neighborhood with 21 lots, 1 entrance, 2 streets and a cul de sac. Russell Park is minutes from Wilderness Estates and offers swimming and picnic areas plus more! Roads are paved and lots ARE NOT BUILDER SPECIFIC, so bring your own builder into the mix. Land surrounding Lake Georgetown is owned by the Army Corp of Engineers.
Are you looking for a large acreage Horse Property in Williamson County just minutes from Downtown Georgetown? Look no further than this 14.187 acres in the esteemed River Place Estates where rustic meets refined luxury. Custom acreage homesite where the horses have plenty of room to roam. Excellent soil and trees with fence and public water source. Covenant restrictions in place to ensure value. Build your dreams in River Place Estates.
NO Deed Restrictions. NO HOA, ETJ or city tax. Rare 9+ acre lot (Georgetown ISD) & just 3 miles from I-35. Lot can be Commercial, Residential OR BOTH! Lot has wet weather / dry creek, amazing vies & lots of privacy. Need septic but electric & private water on nearby property. Currently in process of subdividing entire 18acres. Please do not trespass without permission / appointment. Buyer to verify all info. **Shared driveway w/easement provides access to lot but separate driveway could be installed.**
NO Deed Restrictions, NO HOA, NO ETJ + NO City Tax. Use as Commercial And Residential! Bring All Horses! NEW 4/3 Mobile Home with MIL suite & more than 5 Acres. Home Flooring replaced, NO Carpet! New 3 Car Garage & Shop. Guest Quarters is 336 sqft, 1 Bed, 1 Full Bath & Full Kitchen. New Septic Tank. 1,000+ sqft of Concrete Patios/Sidewalks. Interior pictures are coming but inside is PERFECT. Currently subdividing entire 18 acre property. Buyer to verify all info before closing.
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I liked MiWi enough that I gladly purchased it to run on my iPhone 3G. It worked well and I was satisfied with the features. I was very suprised to find that when I upgraded to the iPhone 4, the older version of MiWi no longer worked. My only option seemed to be to upgrade to the new version of MiWi, which only feature seemed to be that it worked on the upgraded phone OS.
I appreciate that the developer is giving previous owners a break on the price to get the upgraded version, but I don't think it is very ethical to draw upon paid customers for yet more money to simply ensure that the application they paid for, continues to work on the new version.
Yes, I know software companies do this all the time. But there are also those that don't. It is hard to justify the expense to upgrade to MiWi 4 which does not really add anything more than tweaks and bug fixes.
I guess that is the difference between the App store, and jailbreaking and paying for third party apps. Apps on the App store are supported much better and a vast majority of upgrades are gratis. I just want the app that I purchased to work on my upgraded phone like every other app that I have purchased. MiWi is the only application in dozens that I have purchased that wants more money to continue working.
I think I am going to cut my losses. I don't feel like paying an upgrade fee for MiWi every time Apple upgrades the phone's OS.


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Wondering if the real estate market is still good in northeast Ohio?
Ever wonder what or why the other Realtor did or didn't do something?!
Check out this week's blog below!
Sometimes it's just easier to make a video than type out the words.. so even though I'm in my lounge clothes, here goes! Oh, and
Buckle your seatbelts, Cleveland, because the real estate market has been on fire since last spring with no signs of slowing. We've been seeing multiple
My grandmother used to tell me, "Each morning you wake up, you have a choice. You can choose to be in a good mood or


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CLN is creating an interactive platform for members to benefit from the knowledge of all. We envision lively and diverse discussions over various issues, solutions offered to various questions and governance challenges. There are several ways to engage with others CLN members on this site:
Discussions – As a CLN Member, you can post discussion topics to share ideas, experiences and information, or you can comment on other discussions which you find of interest.
Director Abby – Use this area to pose questions or offer your solution to specific questions posted by others. These are shorter than Discussion posts, and do not present information. Since questions can cover potentially sensitive topics, you have the option to post questions and responses anonymously.
Archives – This is the CLN Reference Section where you can access reports, webinar recordings, and news articles. All are searchable using keywords.
Instant Poll – Both Members and site visitors can participate in quick, anonymous poll questions. Past polls are available for viewing as well.
Registered CLN website users will have the ability to protect their privacy through anonymous submissions of questions to Director Abby. Only CLN members will have the opportunity to respond and view e responses for Director Abby questions. Our vision includes directors and industry members collaborating, agreeing and disagreeing on how to solve complicated challenges facing our cooperatives, their members, and their communities. Become a member today and enjoy the benefits below for free.
Join today while you research and build relationships so you can be a better director for your co-op, its members and its community all for free.
CLN is growing its membership to support the relationship building for all directors. We qualify each member to ensure we are keeping the hackers out.
CLN Principal Member Benefits (current and former REA Directors)
- Director members are eligible to run for and vote for CLN board positions.
- Members can now maintain their relationships with other directors and CLN members from across the country.
- Members can create profiles on the CLN website so other members can see your area(s) of expertise and interest. Only members can view the portions of a profile selected to share.
- Members can vote on polls, submit poll questions and view the results from current and archived polls.
- Members can submit discussion topics and post comments on other discussion threads.
- Members can be part of the Director Abby solution and offer solutions to the questions proposed
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- Members can search the growing repository of articles, discussions, Director Abby solutions, program snapshots, and any other resource shared.
- Members will enjoy free registration for webinars and online events (for now).
- Members can access the member directory.
- Members can access the entire CLN website.
Advisory (or Non Voting) Members
- All Member Benefits above, aside from eligibility to run for Board positions, and voting privileges.


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Personalized Tiny size Comfort Soft Wrap harnesses allow you to add your dog's name, up to 7 characters, in the thread color of your choice. Larger sizes are available with different name and phone options, but please make sure you choose the proper size as they can't be returned.
Comfort Soft Wrap harnesses are extremely lightweight with soft mesh-layered material providing a padded feel on the inside with a honeycomb outer layer which is very breathable. Two-Tone styling provides a more refined appearance and the coordinating piping is super soft, almost velvet-like, and will not rub or irritate your dog's skin.
The step-in style harness makes it a breeze to put on and even easier to take off. There is a single quick-release buckle on the back side which brings 2 d-rings together for the leash attachment. Girth adjustments are made form the rear straps going from the shoulders back to the chest area.
It's best to measure your dog's girth while they are standing on all four legs using a soft ruler (or string to be measured later) around the widest part of the chest behind the front legs and pull slightly taught.
Price varies by size. See Additional Info for size chart.
Ships via First Class Mail only to the United States
|SIZE CHART (in inches)
|13" - 15"
|16" - 19"
|19" - 23"
|22" - 28"
|28" - 36"
Great little vest for our toy poodle. Wish there were more personalization options such as longer name or font options. Took longer than expected for delivery.
I really like the harness the only thing I don't care for. Is that you can't see your Raya's name I should of got it in white threads I ordered 3 others before and I did the same thing wrong color for the girl one the male ones were in white you can see them I would advise to redo the website that you can accually preview the name on the harness before purchasing it!!!
I like the harness but I do think the name on it could have been bigger!!! All in all its a great harness!!
This little harness was just what we were looking for. We had looked in all of the pet shops and could not find what we were looking for. Then I went to GW Little and found exactly what we were looking for. It fits our little Minpin and she does not even notice it is on.
Nice coloring, the white lettering really stands out nicely on the orchid color. The clasp is so small it tends to be difficult to unclip. And even though I measured my dog accordingly, she sometimes will get her paw stuck in the head area of the harness, otherwise it fits her girth wise. I think she just needs to grow just a bit more. The harness is very nice for the price and pup is slowly adjusting. Although my pup has a bit more growing to do I would still highly recommend this harness.
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Tutorial zanahorias fondant http://carminaenlacocina.blogspot.com.es/2015/05/tarta-de-zanahoria.html
Paper Hyacinth Tutorial Video Instructions
Learn How to Quill a darling Heart Shaped Mother's Day Paper Craft Gift Idea via Paper Chase - Moms and Grandmas will love these pretty handmade works of art! The BEST Easy DIY Mother's Day Gifts and Treats Ideas - Holiday Craft Activity Projects, Free Printables and Favorite Brunch Desserts Recipes for Moms and Grandmas
Cars galore? Try this fun display!
Magnetic knife holders from Ikea! Love this toy organization idea!
Afwasbakjes tuin en balkon DIY kinderkeuken. Kitchen for kids garden and balcony.
A clever idea for displaying your child's art pieces is in a frame with mini-pegs - easy to swap out, and can be mixed and matched with different colours!
DIY Dollhouse made from a Bookshelf.
An old boat turned charming sandbox, just right for all kinds of creativity! houzz.com/kid-friendly-backyard-ideas


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Shenzhen Beike Cell Engineering Research Institute
Shenzhen Beike Cell Engineering Research Institute
Liu P.C.,Chinese University of Hong Kong |
Lu G.,Chinese University of Hong Kong |
Deng Y.,South University of Science and Technology of China |
Wang C.D.,Chinese University of Hong Kong |
And 5 more authors.
PLoS ONE | Year: 2017
Glioblastoma is a common malignant brain tumor and it is refractory to therapy because it usually contains a mixture of cell types. The tumor necrosis factor-related apoptosis inducing ligand (TRAIL) has been shown to induce apoptosis in a range of tumor cell types. Previously, we found that two human glioblastoma cell lines are resistant to TRAIL, while lovastatin sensitizes these glioblastoma cells to TRAIL-induced cell death. In this study, we investigated the mechanisms underlying the TRAIL-induced apoptosis in human glioblastoma cell lines by lovastatin. Furthermore, we have confirmed the anti-tumor effect of combination therapy with lovastatin and TRAIL in the subcutaneous brain tumor model. We showed that lovastatin significantly up-regulated the expression of death receptor 5 (DR5) in glioblastoma cell lines as well as in tumor-bearing mice with peri-tumoral administration of lovastatin. Further study in glioblastoma cell lines suggested that lovastatin treatment could inhibit NF-κB and Erk/MAPK pathways but activates JNK pathway. These results suggest that lovastatin sensitizes TRAIL-induced apoptosis by up-regulation of DR5 level via NF-κB inactivation, but also directly induces apoptosis by dysregulation of MAPK pathway. Our in vivo study showed that local peri-tumoral co-injection of lovastatin and TRAIL substantially reduced tumor growth compared with single injection of lovastatin or TRAIL in subcutaneous nude mice model. This study suggests that combined treatment of lovastatin and TRAIL is a promising therapeutic strategy to TRAIL-resistant glioblastoma. © 2017 Liu et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Yang W.-Z.,Guangdong Medical College |
Zhang Y.,Shenzhen Beike Cell Engineering Research Institute |
Wu F.,Guangdong Medical College |
Min W.-P.,University of Western Ontario |
And 7 more authors.
Journal of Translational Medicine | Year: 2010
Background: The current paradigm for cord blood transplantation is that HLA matching and immune suppression are strictly required to prevent graft versus host disease (GVHD). Immunological arguments and historical examples have been made that the use of cord blood for non-hematopoietic activities such as growth factor production, stimulation of angiogenesis, and immune modulation may not require matching or immune suppression.Methods: 114 patients suffering from non-hematopoietic degenerative conditions were treated with non-matched, allogeneic cord blood. Doses of 1-3 × 107cord blood mononuclear cells per treatment, with 4-5 treatments both intrathecal and intravenously were performed. Adverse events and hematological, immunological, and biochemical parameters were analyzed for safety evaluation.Results: No serious adverse effects were reported. Hematological, immunological, and biochemical parameters did not deviate from normal ranges as a result of therapy.Conclusion: The current hematology-based paradigm of need for matching and immune suppression needs to be revisited when cord blood is used for non-hematopoietic regenerative purposes in immune competent recipients. © 2010 Yang et al; licensee BioMed Central Ltd.
Di G.-H.,Tianjin University |
Jiang S.,Shenzhen Beike Cell Engineering Research Institute |
Li F.-Q.,Beijing Institute of Radiation Medicine |
Sun J.-Z.,Chinese PLA General Hospital |
And 4 more authors.
Cytotherapy | Year: 2012
Background aims. Mesenchymal stromal cells (MSC) have been shown to be a promising candidate for tissue regeneration and cancer therapy. However, their therapeutic potential against chemotherapy-induced side-effects remains unclear. Methods. We treated murine Lewis lung carcinoma (LLC) and xenograft human colon tumors with adriamycin (ADM) for 3 consecutive days followed by one intravenous (i.v.) injection of human umbilical cord (hUC) MSC for several cycles. Results. MSC treatment mitigated ADM-induced cardiomyopathy, reduced the extent of ADM-induced apoptosis in intestinal crypts, suppressed body weight loss in mice treated with ADM and increased the survival rate of mice treated with a lethal dose of ADM. The examination of hematologic parameters indicated a moderate recovery in MSC-injected mice. Systemic administration of MSC did not increase the growth of murine LLC cells and human colon carcinoma in vivo while it strongly inhibited the lung metastases of LLC cells. Conclusions. We evaluated the prophylactic and therapeutic action of hUC MSC on the chemotherapy agent ADM-induced side-effects in two different tumor models. Our observations suggest that MSC can be used as auxiliary means in chemotherapy for certain tumor types. © 2012 Informa Healthcare.
Mesples A.,Diabetes Education and Research |
Majeed N.,Shenzhen Beike Cell Engineering Research Institute |
Zhang Y.,Shenzhen Beike Cell Engineering Research Institute |
Xiang H.,Diabetes Education and Research
Medical Science Monitor | Year: 2013
Background: Bone marrow stem cell treatment has been proven a promising therapeutic strategy and showed significant results given the strong immune modulating properties. We have investigated the safety and efficacy of autologous bone marrow stem cell transplantation through liver puncture in two patients with recently diagnosed type 1 diabetes mellitus. Material/Methods: The procedure was approved by the Institutional Ethics Committee. In 2011, in three young patients, type 1 diabetes mellitus diagnosis was confirmed, with the presence of positive antibodies and ketoacidosis. Two patients was treated with autologous bone marrow stem cell stimulated with filgrastim and transplantation, through liver puncture, as immune modulators. One patients was treated with conventional treatment and participate in this experiment as a control group. The families of the patients signed the informed consent. No specific statistical analysis was performed. The patients had less than 8 years old, diagnosis of type 1 diabetes for less than 60 days, body mass index less than 22 kg/m2, normal complete blood count, coagulation and renal function, no lesions in target organs, glycosylated hemoglobin (HbA1c) level less than 13.70%, c-peptide level less than 0.67 ng/ml, positive results of Islets Cells Antibody (ICA), Glutamic Acid Decarboxylase (GAD) and insulin antibody. Results: Conclusions: In two patients treated, the follow up at 12 months showed negative value in ICA, GAD and anti insulin antibody levels, with an increased levels of c peptide and decreased levels of blood glucose and HbA1c. PERSONAONLY Treatment with autologous bone marrow stem cells is easy and effective as it reversed the production and effect of anti pancreatic islet antibody and significantly resulted in an increased c-peptide concentration. © Med Sci Monit, 2013.
Jiang B.,Central South University |
Zhang P.,Central South University |
Zhou D.,Central South University |
Zhang J.,Shenzhen Beike Cell Engineering Research Institute |
And 2 more authors.
PLoS ONE | Year: 2013
Objectives:To treat traumatic optic neuropathy (TON) with transplantation of human umbilical cord blood stem cells (hUCBSC) and explore how transplanted stem cells participate in the neuron repairing process.Methods:A total of 195 Sprague-Dawley rats were randomly assigned to three groups: sham-surgery, optic nerve injury, and stem cell transplant group. Optic nerve injury was established in rats by directly clamping the optic nerve for 30 seconds. hUCBSC was microinjected into the vitreous cavity of injured rats. Optic nerve function was evaluated by flash visual evoked potentials (F-VEP). Apoptosis in retina tissues was detected by TUNEL staining. GRP78 and CHOP gene expression was measured by RT-PCR.Results:After injury, transplantation of hUCBSC significantly blunted a reduction in optic nerve function indicated by smaller decreases in amplitude and smaller increases in peak latency of F-VEP waveform compared to the injury alone group. Also, significant more in retinal ganglion cell (RGC) count and less in RGC apoptosis were detected after transplantation compared to injured rats. The protective effect correlated with upregulated GRP78 and downregulated CHOP mRNA expression.Conclusion:Intravitreal transplantation of hUCBSCs significantly blunted a reduction in optic nerve function through increasing RGC survival and decreasing retinal cell apoptosis. The protective role of transplantation was associated with upregulation of GRP78 expression and downregulation of CHOP expression in retinal cells. © 2013 Jiang et al.
Li T.,Shenzhen Beike Cell Engineering Research Institute |
Li T.,Jilin University |
Li T.,Stanford University |
Chen H.,Central South University |
And 8 more authors.
Human Molecular Genetics | Year: 2014
Aberrant imprinting of the insulin-like growth factor II (IGF2) gene is a molecular hallmark of many tumors. Reactivation of thenormally suppressed maternal allele leads to upregulation of the growth factor that promotes tumor growth. However, the mechanisms underlying the loss of imprinting (LOI) remain poorly defined. We examined the epigenotypes at the gene promoters that control IGF2 allelic expression. Using chromatin immunoprecipitation,wefound that in cells characterized by maintenance of IGF2 imprinting, three IGF2promoters were differentiallymodified, with the suppressed allele heavily methylated at histone H3K27 while the active allelewasunmethylated. In the LOI tumors,however, both alleleswere unmethylated,andcorrespondingly there wasnobinding of SUZ12, the docking factor of thepolycomb repressive complex 2 (PRC2),andof the zinc fingercontaining transcription factor (CTCF) that recruits the PRC2. Using chromatin conformation capture, we found that the CTCF-orchestrated intrachromosomal loop between the IGF2 promoters and the imprinting control region was abrogated in cells with LOI. SUZ12, which docks the PRC2 to IGF2 promoters for H3K27 methylation, was downregulated in LOI cells. These data reveal a new epigenetic control pathway related to the loss of IGF2 imprinting in tumors. © The Author 2013. Published by Oxford University Press. All rights reserved.
PubMed | Guangzhou University, Shenzhen Beike Cell Engineering Research Institute and Saban Research Institute
Type: Journal Article | Journal: Stem cell research & therapy | Year: 2016
Interstitial pneumonia in connective tissue diseases (CTD-IP) featuring inflammation and fibrosis is a leading cause of death in CTD-IP patients. The related autoimmune lung injury and disturbed self-healing process make conventional anti-inflammatory drugs ineffective. Equipped with unique immunoregulatory and regenerative properties, mesenchymal stem cells (MSCs) may represent a promising therapeutic agent in CTD-IP. In this study, we aim to define the immunopathology involved in pulmonary exacerbation during autoimmunity and to determine the potential of MSCs in correcting these disorders.Lung and blood specimens, bronchoalveolar lavage fluid cells collected from CTD-IP patients, and human primary lung fibroblasts (HLFs) from patients pathologically diagnosed with usual interstitial pneumonia (UIP) and healthy controls were analyzed by histology, flow cytometry and molecular biology. T cell subsets involved in the process of CTD-IP were defined, while the regulatory functions of MSCs isolated from the bone marrow of normal individuals (HBMSCs) on cytotoxic T cells and CTD-UIP HLFs were investigated in vitro.Higher frequencies of cytotoxic T cells were observed in the lung and peripheral blood of CTD-IP patients, accompanied with a reduced regulatory T cell (Treg) level. CTD-UIP HLFs secreted proinflammatory cytokines in combination with upregulation of -smooth muscle actin (-SMA). The addition of HBMSCs in vitro increased Tregs concomitant with reduced cytotoxic T cells in an experimental cell model with dominant cytotoxic T cells, and promoted Tregs expansion in T cell subsets from patients with idiopathic pulmonary fibrosis (IPF). HBMSCs also significantly decreased proinflammatory chemokine/cytokine expression, and blocked -SMA activation in CTD-UIP HLFs through a TGF-1-mediated mechanism, which modulates excessive IL-6/STAT3 signaling leading to IP-10 expression. MSCs secreting a higher level of TGF-1 appear to have an optimal anti-fibrotic efficacy in BLM-induced pulmonary fibrosis in mice.Impairment of TGF- signal transduction relevant to a persistent IL-6/STAT3 transcriptional activation contributes to reduction of Treg differentiation in CTD-IP and to myofibroblast differentiation in CTD-UIP HLFs. HBMSCs can sensitize TGF-1 downstream signal transduction that regulates IL-6/STAT3 activation, thereby stimulating Treg expansion and facilitating anti-fibrotic IP-10 production. This may in turn block progression of lung fibrosis in autoimmunity.
PubMed | Shenzhen Beike Cell Engineering Research Institute, Jinan University, Sun Yat Sen University and Guangzhou University
Type: | Journal: Molecular psychiatry | Year: 2016
The enteric nervous system (ENS) is recognized as a second brain because of its complexity and its largely autonomic control of bowel function. Recent progress in studying the interactions between the ENS and the central nervous system (CNS) has implicated alterations of the gut/brain axis as a possible mechanism in the pathophysiology of autism spectrum disorders (ASDs), Parkinsons disease (PD) and other human CNS disorders, whereas the underlying mechanisms are largely unknown because of the lack of good model systems. Human induced pluripotent stem cells (hiPSCs) have the ability to proliferate indefinitely and differentiate into cells of all three germ layers, thus making iPSCs an ideal source of cells for disease modelling and cell therapy. Here, hiPSCs were induced to differentiate into neural crest stem cells (NCSCs) efficiently. When co-cultured with smooth muscle layers of ganglionic gut tissue, the NCSCs differentiated into different subtypes of mature enteric-like neurons expressing nitric oxide synthase (nNOS), vasoactive intestinal polypeptide (VIP), choline acetyltransferase (ChAT) or calretinin with typical electrophysiological characteristics of functional neurons. Furthermore, when they were transplanted into aneural or aganglionic chick, mouse or human gut tissues in ovo, in vitro or in vivo, hiPSC-derived NCSCs showed extensive migration and neural differentiation capacity, generating neurons and glial cells that expressed phenotypic markers characteristic of the enteric nervous system. Our results indicate that enteric NCSCs derived from hiPSCs supply a powerful tool for studying the pathogenesis of gastrointestinal disorders and brain/gut dysfunction and represent a potentially ideal cell source for enteric neural transplantation treatments.Molecular Psychiatry advance online publication, 25 October 2016; doi:10.1038/mp.2016.191.
PubMed | Chinese University of Hong Kong, South University of Science and Technology of China and Shenzhen Beike Cell Engineering Research Institute
Type: Journal Article | Journal: PloS one | Year: 2017
Glioblastoma is a common malignant brain tumor and it is refractory to therapy because it usually contains a mixture of cell types. The tumor necrosis factor-related apoptosis inducing ligand (TRAIL) has been shown to induce apoptosis in a range of tumor cell types. Previously, we found that two human glioblastoma cell lines are resistant to TRAIL, while lovastatin sensitizes these glioblastoma cells to TRAIL-induced cell death. In this study, we investigated the mechanisms underlying the TRAIL-induced apoptosis in human glioblastoma cell lines by lovastatin. Furthermore, we have confirmed the anti-tumor effect of combination therapy with lovastatin and TRAIL in the subcutaneous brain tumor model. We showed that lovastatin significantly up-regulated the expression of death receptor 5 (DR5) in glioblastoma cell lines as well as in tumor-bearing mice with peri-tumoral administration of lovastatin. Further study in glioblastoma cell lines suggested that lovastatin treatment could inhibit NF-B and Erk/MAPK pathways but activates JNK pathway. These results suggest that lovastatin sensitizes TRAIL-induced apoptosis by up-regulation of DR5 level via NF-B inactivation, but also directly induces apoptosis by dysregulation of MAPK pathway. Our in vivo study showed that local peri-tumoral co-injection of lovastatin and TRAIL substantially reduced tumor growth compared with single injection of lovastatin or TRAIL in subcutaneous nude mice model. This study suggests that combined treatment of lovastatin and TRAIL is a promising therapeutic strategy to TRAIL-resistant glioblastoma.
PubMed | Guangzhou University and Shenzhen Beike Cell Engineering Research Institute
Type: Journal Article | Journal: Zhonghua yi xue za zhi | Year: 2015
To investigate the immumodulation ability of exosomes secreted from human umbilical cord-derived mesenchymal stem cells (hUC-MSCs).hUC-MSCs were isolated and cultured.Exosomes were isolated from the culture media of the third-generation hUC-MSCs. The expression of specific surface marker CD9 and CD81 were detected by Western blot, and the concentration of hUC-MSCs exosomes(hUC-MSCs-ex) was evaluated by BCA assay. CD3/CD28-stimulated peripheral blood mononuclear cells(PBMCs) from healthy donor were co-cultured with different concentration of hUC-MSCs-ex for 72 h. The percentage of Th17 and Treg cells and the proliferation of CD4 and CD8 T cells were detected by flow cytometry. ELISA was used to test the level of IFN-, IL-6, TNF- and TGF-1.hUC-MSCs-ex inhibited the proliferation of CD4 and CD8 cells obviously,and increased the proportion of CD4 CD25 FoxP3 Treg cells, with high expression of CD81 and CD9. After CD3/CD28 monoclonal antibody stimulated, the percentage of CD45 CD4 Ki67 and CD45 CD8 Ki67 cells were 85.3% 5.6% and 72.6% 6.3%, respectively. Meanwhile, the level of TGF-1 were elevated and the level of IFN-, IL-6 and TNF- were decreased (P<0.05).hUC-MSCs-ex has the immunomodulatory functionin vitro, which could be a new therapeutic agent for the treatment of immune disorders.


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FRI AUG. 18 | Hustle Anniversary Social
Join us as we celebrate at our "Black & White Theme Party" for our Hustle Anniversary Social. Party will be hosted by Xavier Cadeau.
- Time: 9:30 PM to 2:00 AM
- Admission $10
- Dance lesson at 9:30 PM followed by Special Dance Performances later in the evening.
- Location: Balmir Latin Dance Studio, 959 Flatbush Avenue, Brooklyn, NY 11226


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Yoga challenges the mind and body without the violence and hurt feelings of full-contact chess. Steer clear of overaggressive pawns with today's Groupon to My Addiction Cycling and Yoga in North Miami Beach. Choose from the following options:
My Addiction Cycling and Yoga's students improve whole-body fitness with a full schedule of classes, including spinning and yoga sessions for all skill levels. During basic yoga classes, instructors illustrate each movement and guide classes with simple, clear directions in both English and binary. During Vinyasa Power yoga, students move from one pose to the next with balance-challenging movements punctuated by purposeful breathing exercises to help focus concentration. Hatha yoga incorporates traditional poses, controlled-breathing exercises, and meditation throughout the one-hour session, working out body and mind more effectively than a visual acuity test for the third eye.
CoupFlip is a marketplace for people to buy and sell deals from "daily deal" (also known as "group buying") sites such as Groupon. On CoupFlip you can buy deals you missed, look for interesting deals in your area, or sell any deal you bought and won't use. The purchase is immediate - pick the deal, pay, download the voucher instantly and enjoy. Every voucher is guaranteed to be authentic by CoupFlip. For sellers, we provide the opportunity to sell your unwanted deal immediately without the hassle of listing your voucher and praying someone comes along and decides they feel like buying it.
It is completely free to buy and sell vouchers on CoupFlip!
See our FAQ page!
Daily deals make it possible for you to try something new or indulge in something lavish without the high price tag these things usually come with. If you ever have the need to buy and sell deals at any time, we're here to help. At CoupFlip, there's no need to worry about limited time offers on city deals or the long wait for a buyer.
What makes our listing different is that you can feel free to browse through our selection of vouchers at your leisure and pick the ones that you need. Thinking of going out for a meal or planning a vacation? Use our search bar to find the best deals you might have missed on Groupon.
If you're thinking of a Groupon return because you've changed your mind about a purchase, why not consider selling the voucher through us instead? We'll handle the work of offering your last minute deals to interested buyers.
Buy or sell coupons without any difficulty. Here at CoupFlip, we promise you a convenient way to buy and sell deals at any time.


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Hey guys!
So anyone who's been reading my blog for a while will know just how much I love Lush bath bombs. And Lush in general actually. It occurred to me that I hadn't done a review of my FAVOURITE Lush bath bomb yet, so today that's changed...
I apologise for the mass of photos BUT HOW BEAUTIFUL IS THIS BATH BOMB.
Intergalactic smells of a mixture of peppermint and grapefruit, which is invigorating and awakens the sense as soon as it hits the bath water. The smell is beautiful, but the real magic comes when you pop it into your bath. The colours are mesmerising and I find myself staring at it fizz every time I use it. The colours are beautiful and it leaves the bath the most beautiful shade of blue, making me feel like a space mermaid - a great feeling.
There is one aspect of this ballistic that divides opinion, however. That is glitter. The bath bomb is FULL of it. When you leave the bath you will have a layer of glitter on you, and you will need to rinse your bath of it. When I brushed my hair afterwards, specks of glitter floated out of my hair. It was glorious. I love glitter, so this is not even a slight problem for me, but if you hate glitter, I recommend that you avoid this.
Have you tried this? What's your favourite bath bomb?


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We've all heard about it. The capsule wardrobe. It's all the rage these days (and yes, I want to try it once we move into the house). But I've always wondered how difficult it would be to stick to the capsule. Whether you edit to the magic 37 pieces or simply attempt to streamline a bit for each season, I think…
Home › Ideas + Inspiration › 5 Clothing Racks Made for the Capsule Wardrobe
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United states
FCC halts nine companies from participating in the 'Lifeline' program
It provides subsidized home internet service for low-income households.
After Math: Game over
Life should come with a reset button.
A newsletter a day keeps the FOMO at bay.
German Intel chief: Russia is trying to 'destabilize' the country
He blames the same Russian hackers that infiltrated the American DNC this year for the attacks.
The USS Zumwalt can't afford its own $800,000-per-round ammo
Maybe they'll use railguns instead.
The Pax Era aims to be the Keurig of vaporizers
Get your pot in a pod!
US builds a $100 million African drone base to fight Boko Haram
Central Niger is a key ally in the fight against militant extremists.
Uncovering the intersection of art and technology - Nov 16, 2017
Julian Assange: I'll turn myself in if Chelsea Manning walks
That's not how this works. That's not how any of this works.
New Snowden docs suggest Shadow Broker leak was real
Looks like those actually are the NSA's hacking tools up for auction.
US Navy to arm its submarines with 'Blackwing' spy drones
The hunt for Red October is about to get much easier.


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Brittany Schock / Asst. photo editor
Nearly a year-and-a-half after Kennedy Commons closed its doors for a total renovation, the redesigned dining option features a new menu, restaurant and energy-efficient aspects.
The total project budget for Kennedy Commons was more than $12.5 million, according to the Facilities Operations and Development budget.
Karri Benishek, the marketing manager of University Residences and Dining Services, said Kennedy Commons was the first eating option on Ohio State's campus. She said this historic building was renovated close to its original splendor and will now have a new, all-you-can-eat dining experience for south campus.
Kennedy Commons, located at 251 W. 12th Ave., re-opens with added air conditioning and restored traditional architectural features, Benishek said.
The Kennedy Commons renovation is the first phase of the Food Service Master Plan to renovate traditional dining commons to better accommodate the demands of students, faculty, staff and visitors on campus, Benishek said.
The Kennedy Commons project focused on the interior organization within the complex, Benishek said. The dining areas received a complete interior remodel, as well as an improved serving line, additional seating and new food offerings.
"The biggest change between the old Kennedy and the remodel would be the style in which we serve students of the university," said Daniel Hall, student manager at Kennedy Commons. "Previously, Kennedy consisted of a limited selection of food items that was on a one-week rotation. Everything was based upon a four-week master static menu, so the first week of food would repeat the fifth week. The second week would be the same as the sixth week. It was very limiting, considering that there was only five to eight items each week to choose from."
Now, the food will consistently change each week of the quarter, Hall said. Since the options are constantly changing, the students and guests will have an extensive menu of items to choose from.
"It is no longer a 'cafeteria.' It is now, for lack of a better word, a food court. You can walk into Traditions at Kennedy and order a burger from one station that has multiple other choices and come back the next day and order Huevos Rancheros from another station that also has multiple choices," Hall said.
The old infrastructure has been improved by creating a new entrance and improving the energy efficiency of old systems. Benishek said the renovations attained a certification from Leadership in Energy and Environmental Design (LEED). According to their website, LEED certifications are given to construction projects that implement "practical and measurable 'green' building design, construction, operations and maintenance solutions."
John Church, head of the Kennedy Commons kitchen for the past three years, said the new kitchen design will be more functional for students and guests, "which will provide better service and products."
Kennedy Commons will also now house the newest retail operation in campus dining services: 12th Avenue Bread Company.
12th Avenue Bread Company features artisan-bread-inspired sandwiches, fresh soups, salads, morning quiche and pastries, according to the OSU Student Life website. Inside, there will be indoor tables and booths, along with outdoor seating options, highlighted with bamboo trim work, and olive, persimmon and ivory-colored accents.
"When you spend a lot of time at work, your staff is what makes it worth it," said Nathan Darder, operations manager of Kennedy Commons. "Over the past weeks they have worked so hard to get everything set up and organized and trained to make sure we are successful. We received the building on Sept. 3 and served our first meal on the 14th. They have been amazing."
The new Kennedy Commons, with its transition from a single-cafeteria-style serving line to a serving area with multiple stations, will have its soft opening this Tuesday with samplings throughout the week, Benishek said. It will have multiple managers, a full time staff and 200 student-employees, Darder said.
Hours will be Monday through Friday, breakfast from 7:30 a.m. to 9:30 a.m., lunch from 11 a.m. to 2 p.m. and dinner from 4:30 p.m. to 8 p.m. On Saturdays and Sundays The Commons will be open 10:30 a.m. to 6 p.m.


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What Was Your 2006 Guilty Pleasure Food?
Today marks the end of a year and that means it's time for New Year's Resolutions (be sure to put yours in FitSugar's Declare IT group). For many of us, one of those resolutions will be to "cool it with the guilty pleasure food," but before you do that, fess up and let us know about your dirty little 2006 secret.
What was your 2006 guilty pleasure food?
I'm talking about the food that you try and hide from your friends and family!


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I regularly teach courses in Managerial Economics. I have experience teaching the course at many levels, including undergraduate business, MBA, Masters in Finance, and Masters in Management.
In addition, I have taught several Ph.D. courses including Microeconomics for Business Students, Game Theory, and Applied Game Theory. Recent syllabi for Ph.D. Game Theory can by found here (Fall 2016 and Fall 2015).


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Mercy Foundation Provides Loan
Microfinance Services RecipientThe hub of the Kenyan Coast is Mombasa, and this is where you will find the barber shop of Alfayo. Alfayo is a father who has three children. When asked what his key attributes are, he will quickly say that he is reliable. He has been working within a barber shop for the past seven years, though this has not been without challenged. The largest challenge is the lack of electricity, which sometimes hinders his work. His barber shop mainly caters to men, and it is strategically located within a residential area. He has already grown his business with two previous loans, and he is now looking to get a third loan. He applied for his loans through the SMEP Microfinance bank, and is a customer who pays back as expected. With this, he shall get a hair-cutting machine. Alfayo's loan was locally administered by The SMEP Microfinance bank. This is a Kiva partner and non-governmental organization that is fully committed to alleviating poverty in the country, by ensuring that people are empowered. The organization also helps people work towards self-sustainability of marginalized populations.
Microfinance Services PartnerWith the help of Kiva and the SMEP Microfinance bank, the Mercy Foundation was able to provide all the funding for Alfayo's $350 loan. These organizations, along with this microfinance bank wish to help others. This is so that they are able to change the lives of thousands of financially underprivileged people by giving them microfinance servicesthat could help them find a way out of poverty. Rather than just give them money in the form of aid, this method also helps people work towards self-sufficiency. Kiva brings socially responsible enterprises like the Mercy Foundation together, while the SMEP Microfinance bank ensures that the funds that these individuals provide find their way to the people that need them the most. This formula works well because all the parties involved have the same aim, to ensure that needy entrepreneurs gain access to microfinance services. Alfayo is now on the way to realizing his dream of elevating his standard of living. Should you also like to change someone's life in the same way, you should pay a visit to www.kiva.org. There you will thousands of entrepreneurs that are in need of funding. Notes
- This article is based on https://www.kiva.org/lend/803415
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We are on the verge of crowning three featherweight champions this year, and a lot of people have seen this as a problem. The UFC???s announcement in December started it all as they announced they will crown their first 145 champion with Holly Holm versus Germaine de Randamie at UFC 208 February … [Read more...]
2016 in the Women's MMA Division by the Numbers
When we posted the half years numbers in July, we had our doubts we would reach more than 700 pro female bouts in MMA. The last six months exceeded expectation. The last half saw 385 bouts with three months out of the six topping the most fights per month list. On average there was 13.5 bouts per … [Read more...]
Cris Cyborg: The Facts and the Scenarios after USADA
After USADA and the UFC announced last week Cris ???Cyborg??? Justino failed an out-of-competition test, the internet went crazy. A lot of speculation came about without a full set of the facts being laid out, which is sorry to say, becoming more prevalent in all media. Let us breakdown the actual … [Read more...]
UFC Announces Featherweight Division – Holm vs. de Randamie to Vie for First Title
UFC President went through with his promise on creating a featherweight division, but the first champ won???t be Cyborg Justino. Fox Sports reported Tuesday former bantamweight champion Holly Holm will face Germaine de Randamie for the initial UFC 145 title at UFC 208 ??February 11th in Brooklyn, … [Read more...]
IMMAF European Open 2016 Coverage
Some of the best amateur female talent have descended in Prague in the Czech Republic for the second annual IMMAF European Open. Competitors from over a dozen countries will look to shine on the amateur???s biggest world stage. Several World and European champions will look to face a fresh batch of … [Read more...]
InvictaFc 20 Aftermath – What is next for the Athletes
It was a surprising ending to what has been a long 20 card journey for InvictaFC as a new champion was crowned in the bantamweight division. Russia???s Yana Kunitskaya submitted champion Tonya Evinger to end her 9 fight win streak and take the belt, much to the shock of the MMA world. Kunitskaya … [Read more...]
Miesha Tate: A Career of Adversity and Triumph
It was a sad night for the women???s divisions of MMA. After losing to Raquel Pennington by decision this past Saturday, Miesha Tate stated she was hanging up her gloves. ???It???s time for the next generation??? Tate explained in her post fight comments. When I first started covering the women???s … [Read more...]
Beautiful Brawlers Announces All Pro Boxing Card for December
With the news of women???s boxing getting a boost in 2017, one of the first event to feature amateur and pro female boxers will help kick start it in 2016. Beautiful Brawlers announce an all pro female boxing show at the Pacifica Cages in??Pacifica, California December 3rd. It will be the first of a … [Read more...]
Kalyn Schwartz Signs to Invicta; Faces Tiffany Van Soest in Debut
InvictaFC announced Tuesday who will face Muay Thai champion Tiffany Van Soest in her promotional debut. Undefeated amateur fighter Kalyn Schwartz (6-0) will be making her pro debut at InvictaFC 19 in Kansas City September 23rd against the Muay Thai superstar. A dedicated Marine, Schwartz started … [Read more...]
InvictaFC 19 Adds Van Soest; Aldana vs. Van Duin; Plus 4 More Bouts
InvictaFC announced Friday six more bouts will be added to the two title matches for its upcoming 19th outing in Kansas City, Missouri September 23rd. The featured contest will see former featherweight title challenger Faith Van Duin against former bantamweight title challenger Irene Aldana. Van … [Read more...]


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Tag Archives: God
He is an awesome God!
How wonderful and awesome is our God? Read the first few chapters of Genesis and you will know just how great and powerful is our God. To think He created our entire universe just by speaking it into existence. You … Continue reading
Posted in Christian blog Tagged Creation, faith, God, He is an awesome God!, Jesus, life Leave a comment
Be Good Times Christians
The children of Israel as a whole, as the story is told in our Old Testament, seemed to be bad times followers of God only. If you read through the period of the Judges, when they were governed by their … Continue reading
Posted in Christian blog Tagged Be Good times Christians, christian life, God, We need God always Leave a comment
Patience is often seen as a godly virtue and indeed it is one. God, Himself, is the greatest example we have of patience that we should be ready to emulate and incorporate into our lives. God shows great patience in … Continue reading
Posted in Christian blog Tagged God, Paience Leave a comment
2017 Florida College Lectures
Well, the 2017 edition of the Florida College Lectureship is in the books. We attended last week and found the subject of the divine pattern for marriage to be a very interesting one. I have never personally had the honor … Continue reading
Posted in Christian blog Tagged Florida College Lectures 2017, God, Marriage God's Plan, serving God Leave a comment
If you love me…
Jesus said in John 14:15: "If you love Me, keep My commandments." The New Testament its original Greek used two different words that are translated love in our English bibles. The first is agapaho which is a higher love in … Continue reading
Posted in Christian blog Tagged Biblical love, God, Jesus Leave a comment


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Caramel Coated Walnuts
READY IN: 1hr 15mins
Recipe by Tasty Buds
A very tasty treat if you like candy coated nuts. This recipe came from the back of Aldi's Southern Grove walnuts 4 cup bag.
Ingredients Nutrition
- 4 cups walnuts
- 1 cup brown sugar
- 1⁄2 cup margarine
- 1⁄4 cup white corn syrup
- 1⁄8 teaspoon cream of tartar
- 1⁄4 teaspoon salt
- 1⁄2 teaspoon baking soda
Directions See How It's Made
- Mix together brown sugar, margarine, white corn syrup, cream of tartar, and salt.
- Bring to a boil for 3 minutes stirring often. Remove from heat.
- Add baking soda and stir well until settles.
- Pour over walnuts and stir until well coated.
- Pour into a large pan. Bake at 200 degrees for 1 1/2 hours, stirring every 15 minutes.


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New Dell Studio 15" Notebook. 2.16Ghz C2D, 3gig, 250GB, 256meg graphics, Cam, BT, $1258 delivered
Click through and enter R510706N-WEB into the ecode finder boxes to reach this deal. At checkout use coupon code 3912189E460D for 10% discount. Coupon expires end of June!!
Dell Studio 15 Laptop
Intel Core2 Duo Processor T5850. 2.16 GHz, 2MB Cache, 667 MHz FSB
3GB (1x2GB+1x1GB) 667MHz SDRAM
250GB SATA Hard Drive
Internal 8X DVD + /-RW Combination Drive with dual layer write capabilities
Integrated Stereo Sound
256MB ATI Mobility RADEON HD 3450
15.4 " Widescreen WXGA CCFL (1280X800) TFT Display with TrueLife w/ Camera
Dell Keyboard with Touchpad (English)
6-cell Lithium Ion Primary Battery
Dell Wireless 1510 802.11n Half Mini-Card
Dell Wireless 370 Bluetooth Module
Integrated 10/100 Fast Ethernet
External USB modem
1 Year Limited with Next Business Day Onsite Service
Genuine Windows Vista Home Premium 32 bit SP1 Edition (English)
TOPICS: Computers and Electronics
6 comments
- sandgroper
- kearnsyMorning Sandy, You know what would make this deal so much better? An extra 5% off, use the 10% yellow envelope offer on this deal to get the system for $1258. Just tried the code and works fine...10% expires on the 30th so get cracking scoopers
- sandgroperCheers Kearnsy, I was struggling to find a discount coupon and there it was under my nose :D Dont forget there is bucky cashback too on this!
- dealhunter08damn i just bought the vostro.. this seems better than the vostro 1510 :(
- DaniWhat's the difference between this and Dell™ Inspiron™ 1520? They look the same, similar specification except 1520 has "256MB GeForce® 8600GT" (better card?) and same price.
- kearnsyThe Studio is a premium model placed between the Inspiron series and XPS. If you look at the difference between the 1520, XPS M1530, and Studio 15 you will see that the styling resembles the M1530 with the tapered slim look to the front with the rolling hinge design. The Studio has the only 15" WLED screen on any of Dell's laptop lineup so that is a definate selling point. It also is the only 15" screen model from Dell that has a backlit keyboard. For resale value the 1520 is a dime a dozen nowadays, the Studio 15 has just been released so will have better resale (should have) in time to come. Really at $1258 it really is a steal as Dell trys to establish the range, and the deals that come afterward are probably going to be a lot more expensive. I would say the Studio series wont see heavy discounting for at least 6 months (unless it does not sell, which I don't think will happen).Dani;54481What's the difference between this and Dell™ Inspiron™ 1520? They look the same, similar specification except 1520 has "256MB GeForce® 8600GT" (better card?) and same price.


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The Cylons were created by man. They evolved. They rebelled. There are many copies. And they have a plan.And so, too, does Mitt Romney, in his apparent affirmation of his true Cylon nature. In fact, he has 59 plans for the economy, released yesterday in a 160 page economic tome, complete with 137 footnotes, that will test even the most caffeinated reader not to be induced into a boredom coma. Even the WSJ is turning up their noses at it.
Obviously this is a strategic move, which couldn't come at a better time with Romney losing his front-runner status to fellow Cylon Rick Perry. (PS-- you can tell they're fracking skinjobs by noticing how well-coifed their hair is. John Edwards? Also a toaster.)
While obviously long in the works, this is being released right on schedule to show everyone that Mitt knows how to have a plan-- a big, detailed plan!-- and nobody is going to have a bigger or better one. Perry's retort is just "Well, look at my record of job creation in Texas. . . . just not too closely or you'll see that I had nothing to do with real job creation and most of the new jobs in Texas are either minimum wage or public sector (evil, evil government!) jobs." Mitt's plan is obviously to take his plan and turn it into twenty seven eight-by-ten color glossy photographs with circles and arrows and a paragraph on the back of each one explaining what each one was.
But Mitt has The Plan.
Good luck with that.
I mean, seriously. Obama won on Hope and Change, not detailed policy proposals. (And what policies he did have he immediately caved on when negotiating with Congress) George W. Bush had a three point plan for EVERYTHING, and that was it. 3 points. Bill Clinton in 1992 had a campaign mantra: "It's the economy, stupid. Change vs. more of the same, and Don't forget Health Care." Boom, that was it.
And this is not just a product of our modern shortened political attention span. FDR's Four Freedoms speech. Truman's inaugural with the Four Points. The Gettysburg Address- which is shorter than this blog post. This is what Americans like. Terseness. Moral clarity.
You know what they don't like? Reading. Remembering more than a few things. Ross Perot and his charts and half-hour infomercials, Woodrow Wilson's 14 Points, as great as they may have been, were rejected by the American public and gave Wilson a stroke as he tried to whistle-stop across America selling it to the people. And this was in 1917, waaay before people could be distracted by Netflix, Jersey Shore, Angry Birds, and internet pornography.
K.I.S.S.-- Keep it Simple, Stupid. Lay off the 59 points. Mitt, you might be able to beat Obama**. But first you have to beat Perry. And burying him in paper may have shown how smart you were when you worked at Bain Capital as a corporate raider, but not these days, and not against a guy like Perry. You want to bury him in substance? He will bury you in NON-SUBSTANCE.
**== Let me clarify "might". Americans might be able to accept a Latter-Day Saint president. Might. But it's going to be a tough sell as both a Mormon and a Cylon.
All of this has happened before, and it will all happen again.


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Help with my blog, adding link to image, align categories left.
I just downloaded a new theme for my blog, and am having trouble editing it a little bit.
The blog is http://www.murallah.com , and it would help you understand better if you visited it.
Here are the few problems I am having:
(i) I would like to align all the sidebar content on the left sidebar, all the way to the left, just how the content under 'META' is aligned.
(ii) I would like to make the header images (LINKS, CATS, ABOUT etc.) into links as well.
The only code I could find for these images was in style.css, this:
<edit>snip long code</edit>
There is more, I won't post it all though. Notice the url('images/links.jpg') … I cannot figure out how to make those images into pictures.
All help, comments, and suggestions are greatly appreciated.
- The topic 'Help with my blog, adding link to image, align categories left.' is closed to new replies.


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Get inspired by Mother Nature with the smooth, matte wood finish. No trees were harmed in the making.
New York design company S'well has taken the insulated bottle market and tipped it upside down! Style and insulated Thermo bottles are not typically used in the same breath, until now. Designed for performance, S'well Thermo bottles will keep cold drinks cold for 24 hours and hot ones hot for 12 - and they look great while they do it.
Capacity: 750ml
Material: 18/8 double-walled steel, non-toxic, non-leaching and BPA free
Dimensions: 25cm x 6.7cm base diameter


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27380Re: Analog Computers - General description (long)
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- Sep 8, 2012--- In email@example.com, "Dave" <dave.g4ugm@...> wrote:
>I'm really pleased, as an engineers of the 1970's, to see a brief presentation of mechanical analog (differential) computers in the MARCH discussion. This is truly "lost technology" by my standards and I'm glad it's getting support in the UK.
> I have never used an analog computer in anger but I was taught to use them
> as part of my Mathematics degree in 1972/3 and latterly I am part of the
> team that maintains and demonstrates the Hartree Differential Analyzer at
> the Museum of Science and Industry, Manchester England. If you have browser
> other than IE you can see a flash video of the Hartree here:-
> http://www.cs.man.ac.uk/~chl/hartree.html
To answer the original question, about the nature and use of electronic analog computing. If you are interested enough, obtain some books on the subject from the era. Many engineering books about analog computing are available cheaply from Amazon - cheaper than those books on eBay that aren't listed by title, in order to sell them at higher prices. In addition, you can get many of those same books by loan through your local library, from university collections. That service is called "interlibrary loan" and you can talk to your local library about that service.
While it's fun to talk about these things and discuss questions and answers thru email - it's more PRODUCTIVE to do the homework of reading the available literature, and that means paper books. They won't be available for many years longer; that's another discussion. They were designed to explain the use of these analog computers, to people would use them "in anger" as the poster described. You will need to understand differential equations, just as any binary programmer of microcomputers needs to understand Boolean logic and binary arithmetic.
But differential equations STILL describe processes and model systems, from chemical to economic, that are still modeled today. These machines can STILL do some "work" that means something. They won't play Adventure, but you can have an adventure in learning about and using them.
Herb Johnson
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Biological Transmutation; Lifefood and Intestinal Lifecolloid
Biological transmutation; lifefood and intestinal lifecolloid
If you take a three day old fertilized egg and measured the calcium in it; and you take a twelve day old fertilized egg; there can be up to six hundred percent more calcium; a red blood corpuscle has been observed by a researcher to have the ability; where it's been extraverted; I have seen this corpuscle where no nucleic acid exists, nucleic acids and DNA arise from aggregation, fusion and differentiation, which then transformed into an immune cell.
During formation of new life; biological transmutation causes a decrease in some mineral and an increase in other mineral; life colloid within the intestinal tract, have enzymes that assist element become fused with extra neutron, proton and electron; and lifecolloid exists and helps reduce things like potassium which can be converted Into calcium with the addition of a hydrogen atom.
Nascent hydrogen is a negative hydrogen ion; and is shown to cause other element that it comes in contact with to be brought to its boiling point; where such element can be reduced to its proton, neutron and electron soup; current scientific models only can consider transmutation is being occurred with an enormous amount of energy; this is a modern theory; and we can see from the example above that this is not the case.
All proponents of biological transmutation; at the present moment; are not necessarily included within scientific discourse; yet you can perfectly see from the example given; that there is more to the equation; certainly, evidence exists of lifecolloid deep within the earth; biological transmutation of element into gold and things like this; what is being observed is a form of nuclear fusion in biology which is occurring without the requirement of much energy.
Such a phenomenon of lifecolloid; a capacity to input high energy spin Element; lifecolloid assists biological transmutation; reaction happened inside a living body; as well as on the outside; like with a cyclotron; certainly as the year two thousand rolled around; researchers began to observe how nuclear waste was biologically being transmuted into non radioactive element; using lifecolloid; certainly also much experiment show how lifecolloid can transmute manganese into iron; it is a fact that life has been shown to transmutate radioactive effects; making gene inerrancy neutralized; lifecolloid show under certain circumstances; a powerful ability to repair in a low level background of radiation; and, it is a fact that there is enormous anomalies of isotopes that exist in living systems; and certainly nuclear fusion; through process of aggregation, fusion and differentiation; has occurred in biological and lifecolloidal systems.
Little motors existing n biology; for instance, adenosine toriphosphate is spinning one thousand five hundred revolutions per minute; cold fusion is what's really going on in biological transmutation. It is a fact that nuclear biological reactions; are incurred naturally in nature; within lifecolloid which has great application in the fields of geology, biology, physics, cosmology and medicine.
Experiments you can see of trees growing in clay vases; after many years one can be observed that perhaps more soil was there than there was before; but what has grown up in the soil can have much weight; electrons expressed can have turned into hundreds of pounds of wood Bark and root; physiologists have debunked the ideas that any increase in calcium carbonate found in a twelve day old incubated chicken egg was not contributed by the shell; numerous elements created by life as life transmutates; for us to consume what is only necessary, elements are transmutated from one element into another in lifecolloid probiotic.
Water is not even just water is it? Watering in the morning that has perspired out and lighting is extremely horizontal not vertical; and passing through the atmosphere vertically causes water to form into heavy hydrogen; which has a spare neutron and is an isotope of hydrogen; studies show this negative hydrogen ion influences a bud that would have grown into a leaf, and is influenced to become a flower instead.
Jubb's Whitegold and monatomic element are necessary as element to achieve long life, minerals found in biology and nature versus minerals; that are formed like rocks; certainly muriatic acid and nitric acid have been shown to dissolve gold; and is supplied in gold recovery; black alum painted onto the outside of jewelry can cause that gold never to tarnish again.
Monatomic element in biology engages for you; and incurs a semiconducting secondary nervous system; Jubb's white gold has element that is as luminous and soft as pearl; certainly studies show enzymes that were damaged by ultraviolet light can be revived; by monatomic element which is spoken of being even heavier than gold, and is completely incombustible by fire.
Monatomic element as it is oxidized; has been transmutation by lifecolloid; into any necessary element needed; this element brought in through life food; has amphotericness; which is the characteristic of an element that's either an acid or a base; because it can interact with either one, whichever is necessary; you have complex element with a three dimensional structure which is amphoteric.
Elements such as water, ammonia, and various metal hydroxides; have the capacity for amphoteric; as does lifefood; as opposed to crystallized diatomic versions where there is not amphoterics; lifecolloid produce emulsion surfactants; hitch can be anionic or cationic; which exist in jubbs whitegold and lifecolloid probiotic; and are silica based and are complexed by humics and fulvics and lipids; which cause deep cleansing and clearing away of debris.
The body and your intestinal garden you are wrapped around has lifecolloid within; that assist you with biochemical separation and purification; and assists with clathrate on element; and such surfactant crystallizes from body solution in water on a molecular level; little hollow cages, any substance that is in the solution that is small enough becomes trapped within the cage; little hollow sphere are formed which attach to albumin and this process can cause three sides of that clathrate on cage to be open; and to pull things towards itself, gasses such as carbon dioxide can act as a clathrater.
It is a fact that weather engineering at the moment is melting the ice, and methane gas was released, and as this methane is released in such large accounts! it can Be shown to be responsible to latching onto and depleting the ozone! Certainly!
Methane from a cows flatulence counts for the largest percentage of Greenhouse gasses; if you didn't know that you should; burning petroleum is a much less contributing factor, as ice melts off the Sea shelves in Greenland; upper values of carbon dioxide of nitrogen and oxygen in our atmosphere; is not a mixed ratio; enough to cause the clathrate stop this methane to sink this gas, concentrations of nitrogen and oxygen can be equivalent to opening up a can of soda; an effect of a rapid degassing, takes place; no one can say that all the heavy metals such as aluminum and barium being sprayed cannot reach to be blocking out twenty percent of the light; that is reaching the earth at the moment; effecting things freezing or not; and this being sprayed decrease the point where water freezes.
Sun-dried sea salt is amphoteric; and it has magnesium fluorine and iodine within it; where other salts on the market are dead; and not amphoteric at all; you vote in the way that you live your life by what you purchase; and biological transmutation being denied; doesn't have a valid construct or context; and it's a fact that coenzyme q-10 and cobalmine b-12 and essential amino acids and fatty acids are derived within your body as a result of biological transmutation; incurred by lifecolloid in the garden that you are wrapped around; as you have a diversity of lifecolloid within; you have a great intelligence, even digesting something like a cardboard box; everybody knows that a tumor could have digested your neighbors house and it did so because it has a resident lifecolloid; within its intestinal tract; that can break down the cellulose of the wood; lifecolloid can breakdown the cellulose of the wood, and the termite is benefitted from that wood being transmutated, you and it are not any different in the way we were designed.


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Mount of Luna
Definition of Mount of Luna
: a mount located on the side of the hand below lower Mars and across the palm from the Mount of Venus that when well developed is usually held by palmists to indicate refinement, imagination, idealism, and a taste for things romantic and beautiful —called also Mount of the Moon
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Origin and Etymology of mount of luna
luna from Latin, moon
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|"Peter lynch (JIRA)" <j...@apache.org>
|[jira] [Created] (MTOMCAT-156) exec-war should allow creation of exec-war in projects with any packaging type
|Mon, 21 May 2012 05:45:40 GMT
Peter lynch created MTOMCAT-156: ----------------------------------- Summary: exec-war should allow creation of exec-war in projects with any packaging type Key: MTOMCAT-156 URL: https://issues.apache.org/jira/browse/MTOMCAT-156 Project: Apache Tomcat Maven Plugin Issue Type: Improvement Components: tomcat7 Affects Versions: 2.0 Reporter: Peter lynch Assignee: Olivier Lamy (*$^¨%`£) Currently exec-wars in tomcat7 can only be created in projects with packaging 'pom' or 'war'. There are scenarios where one could want to use another packaging type and still create an exec-war. This restriction should be removed. Attached patch removes this restriction. -- This message is automatically generated by JIRA. If you think it was sent incorrectly, please contact your JIRA administrators: https://issues.apache.org/jira/secure/ContactAdministrators!default.jspa For more information on JIRA, see: http://www.atlassian.com/software/jira --------------------------------------------------------------------- To unsubscribe, e-mail: firstname.lastname@example.com For additional commands, e-mail: email@example.com
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There two 5-0 teams in the NFL right now...and one of them is the TEXANS! This past weekend was an amazing one, not only on Monday night, but on Sunday when all of the out-of-town Texans took over Idle Hands. The TV station in Houston even covered it: http://www.khou.com/sports/Die-hard-Texans-fans-hit-the-Big-Apple-to-show-Southern-love-173123481.html
This week, the Texans are on Sunday Night, so come down and enjoy some bourbon, beer and football along with some dinner from That Burger! We'll still be open at Noon if you want to spend the day with us watching all the other games.
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{Disclosure: I received Heinz®, Johnsonville® and Ocean Spray® products in exchange for sharing this recipe. All thoughts and opinions are my own.}
Fall and football season are in full swing – and that means it's time for parties, tailgates, potlucks, holiday gatherings and other get-togethers! Party planning can be almost as stressful as it is fun.This time Heinz, Johnsonville and Ocean Spray have teamed up for the Ultimate Party Meatballs recipe. This delicious and versatile dish is a simple go-to recipe for entertaining!
With a tangy, sweet sauce that is sure to impress, the Ultimate Party Meatballs recipe makes a perfect appetizer or even a main course. Ultimate Party Meatballs
uses just three ingredients that are easy to keep on hand – one jar of Heinz Chili Sauce, a bag of Johnsonville Classic Italian Meatballs and one can of Ocean Spray Jellied Cranberry Sauce. Three ingredients = total tastiness! The recipe can easily be prepared on the stove top or in your slowcooker.
I decided to make the Party Meatballs in the slowcooker,as it was a gloomy day so it was perfect day to make these. You don't have to cook these long as the Johnsonville Classic Italian Meatballs are fully cooked and made with only premium cuts of meat and never any artificial flavors or colors.
The flavoring of these meatballs were awesome~not too tart or sweet,just right! We all agreed that these were one of the best meatballs we have ever tasted. I didn't tell them that they were so easy to make either. I think that we will just keep that our little secret for now!
You can make the recipe at home too~it follows below. I know that you and your family will love them as much as we did.
Sunday, October 20, 2013
Ultimate Party Meatballs Recipe!
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