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In this Issue
January 2017; volume 122, issue 1
EDITORIAL | Cores of Reproducibility in Physiology
REVIEW | Cores of Reproducibility in Physiology
RESEARCH ARTICLES | Aging and Exercise
- Resistance training with instability is more effective than resistance training in improving spinal inhibitory mechanisms in Parkinson's disease
Patients with Parkinson's disease (PD) have motor dysfunction. Spinal inhibitory mechanisms are important for modulating both supraspinal motor commands and sensory feedback at the spinal level. Resistance training with instability was more effective than resistance training in increasing the levels of presynaptic inhibition and disynaptic reciprocal inhibition of lower limb at rest of the patients with PD, reaching the average values of the healthy controls.
- Habitual aerobic exercise does not protect against micro- or macrovascular endothelial dysfunction in healthy estrogen-deficient postmenopausal women
This is the first study to demonstrate that habitual aerobic exercise may not protect against age/menopause-related whole forearm microvascular endothelial dysfunction in healthy nonobese estrogen-deficient postmenopausal women, consistent with recent findings regarding macrovascular endothelial function. This is in contrast to what is observed in healthy middle-aged and older aerobic exercise-trained men.
- Neuromuscular electrical stimulation prior to presleep protein feeding stimulates the use of protein-derived amino acids for overnight muscle protein synthesis
Neuromuscular electrical stimulation (NMES) as well as presleep dietary protein ingestion represent effective strategies to stimulate muscle protein synthesis rates. Here we demonstrate that in older men after a day of bed rest, the application of NMES prior to presleep protein feeding stimulates the use of dietary protein-derived amino acids for overnight muscle protein synthesis by 18% compared with presleep protein feeding only.
- Obesity, type 2 diabetes, and impaired insulin-stimulated blood flow: role of skeletal muscle NO synthase and endothelin-1
Although impairments in endothelial signaling are hypothesized to reduce insulin-stimulated blood flow in type 2 diabetes (T2D), human studies examining these links are limited. We provide the first measures of nitric oxide synthase and endothelin-1 expression from skeletal muscle tissue containing native microvessels in individuals with and without T2D before and during insulin stimulation. Higher basal skeletal muscle expression of endothelin-1 and reduced endothelial nitric oxide phosphorylation (peNOS)/eNOS may contribute to reduced insulin-stimulated blood flow in obese T2D patients.
- Effect of increased and maintained frequency of speed endurance training on performance and muscle adaptations in runners
Ten speed endurance training (SET) sessions improved short-term exercise capacity and 10-km performance, which was followed by further improved short-term exercise capacity, but unchanged 10-km performance after 20 SET sessions performed with either high frequency (4 per 8 days) or continued low frequency (2 per 8 days) in trained runners. The further gain in short-term exercise capacity was associated with changes in muscle expression of proteins of importance for the development of fatigue.
- Flow velocity is relatively uniform in the coronary sinusal venous tree: structure-function relation
A hemodynamic model is developed in the entire coronary sinusal venous tree of the swine heart. A key finding is that the coronary sinusal venous system complies with the area preservation rule for efficient venous return while the coronary arterial tree obeys the minimum energy hypothesis. This model can also serve as a physiological reference state to test various therapeutic rationales through the venous route.
- A pilot study examining the impact of exercise training on skeletal muscle genes related to the TLR signaling pathway in older adults following hip fracture recovery
These pilot data demonstrate that 3 mo of exercise training in older adults recovering from hip fracture surgery was able to mitigate skeletal muscle gene expression related to inflammation and ceramide metabolism while also improving surgical limb lean tissue, strength, and physical function.
- Intermittent parathyroid hormone administration attenuates endothelial dysfunction in old rats
We have demonstrated that intermittent parathyroid hormone administration can rescue age-related vascular dysfunction by improving endothelial-dependent dilation in the aorta of older rodents. This demonstrates a novel potential benefit of parathyroid hormone administration in aging.
- Nasal high-flow therapy reduces work of breathing compared with oxygen during sleep in COPD and smoking controls: a prospective observational study
Nasal high-flow (NHF) therapy can support ventilation in patients with chronic obstructive pulmonary disease during sleep by decreasing the work of breathing and improving CO2 levels. On the other hand, oxygen supplementation corrects hypoxemia, but it produces only a minimal reduction in work of breathing and is associated with increased CO2 levels. Therefore, NHF can be a useful method to assist ventilation in patients with increased respiratory mechanical loads.
- Relationship between obstructive sleep apnea and endogenous carbon monoxide
Endogenous carbon monoxide (CO) levels are recognized to be a surrogate marker of oxidative stress. No study has evaluated both exhaled and blood CO at the same time in obstructive sleep apnea (OSA) patients. Here we provide evidence that exhaled CO levels positively correlated with hypoxia during sleep in OSA patients, but blood CO levels did not, and that continuous positive airway pressure therapy significantly decreased exhaled CO levels in the OSA group, but did not significantly affect blood CO.
- Central and peripheral responses to static and dynamic stretch of skeletal muscle: mechano- and metaboreflex implications
Different modalities of passive stretching administration (dynamic or static) in combination with circulatory cuff occlusion may reduce or amplify the mechano- and metaboreflex. We showed a reduced mechanoreflex response to static compared with dynamic stretching. The lack of increase in central hemodynamics during the combined mechano- and metaboreflex stimulation implicates marginal interactions between these two pathways.
- Renal sympathetic denervation attenuates hypertension and vascular remodeling in renovascular hypertensive rats
The effects of renal sympathetic denervation (RSD) on hypertension, cardiac function, vascular fibrosis, and renal apoptosis were studied in the 2K1C rat model. Results showed that RSD attenuated hypertension, improved vascular remodeling, and reduced vascular fibrosis through decreased sympathetic activity in the 2K1C rat model, but it did not change the kidney size, renal apoptosis, or renal caspase-3 expression. These results could suggest possible clinical efficacy of RSD for renovascular hypertension.
- Rates of performance loss and neuromuscular activity in men and women during cycling: evidence for a common metabolic basis of muscle fatigue
Although men and women differed considerably in their absolute cycling performances, there was no sex difference in the metabolically based exponential time constant that described the performance-duration relationship. Similarly, the fatigue-induced increases in neuromuscular activity were not different between the sexes when compared from a metabolic perspective. These data suggest that men and women have similar rate-limiting mechanisms for short-duration dynamic exercise that are determined by the extent the exercise is supported by anaerobic metabolism.
- Effect of hypohydration on thermoregulatory responses in men with low and high body fat exercising in the heat
This is the first known investigation to compare thermoregulatory responses to exercise heat stress between men with high and low body fat (BF) in a physiologically uncompensable environment while simultaneously examining the confounding influence of hydration status. Both groups demonstrated similar sweating and cutaneous vasodilatory responses when euhydrated, despite vast differences in rectal temperature. Furthermore, in contrast to low BF, individuals with high BF demonstrated similar increases in core body temperature when either euhydrated or hypohydrated.
- Effect of sodium nitrite on local control of contracting skeletal muscle microvascular oxygen pressure in healthy rats
Ischemic conditions as diverse as chronic heart failure (CHF) and frostbite inflict tissue damage via inadequate O2 delivery. Herein we demonstrate that direct application of sodium nitrite enhances the O2 supply-O2 demand relationship, raising microvascular O2 pressure in healthy skeletal muscle. This therapeutic action of nitrite-derived nitric oxide occurred without inducing systemic hypotension and has the potential to relieve focal ischemia and preserve tissue vitality by enhancing O2 delivery.
- Nondestructive cryomicro-CT imaging enables structural and molecular analysis of human lung tissue
The described micro-CT cryostage provides a novel way to study the three-dimensional lung structure preserved without the effects of fixatives while enabling subsequent studies of the cellular matrix composition and gene expression. This approach will, for the first time, enable researchers to study structural changes of lung tissues that occur with disease and correlate them with changes in gene or protein signatures.
- The effect of obesity on the contractile performance of isolated mouse soleus, EDL, and diaphragm muscles
The effect of obesity on isolated muscle function is surprisingly underresearched. The present study is the first to examine the effects of obesity on isolated muscle performance using a method that more closely represents real-world muscle function. This work uniquely establishes a muscle-specific profile of mechanical changes in relation to underpinning mechanisms. These findings may be important to understanding the negative cycle of obesity and in designing interventions for improving weight status.
- Aerobic exercise in humans mobilizes HSCs in an intensity-dependent manner
Here we demonstrate for the first time that mobilization of hematopoietic stem cells (HSC) through exercise is intensity dependent, with the greatest mobilization occurring immediately after high-intensity exercise. As well, we show that exercise is a general stimulus for mobilization: increases in specific HSC populations are reliant on general mononuclear cell mobilization. Finally, we demonstrate no differences in mobilization between groups with different aerobic fitness.
- Nasal high flow reduces dead space
Clearance of expired air in upper airways by nasal high flow (NHF) can be extended below the soft palate and de facto causes a reduction of dead space. Using scintigraphy, the authors found a relationship between NHF, time, and clearance. Direct measurement of CO2 and O2 in the trachea confirmed a reduction of rebreathing, providing the actual data on inspired gases, and this can be used for the assessment of other forms of respiratory support.
- Single passive leg movement-induced hyperemia: a simple vascular function assessment without a chronotropic response
Using the single passive leg movement (PLM) technique, a variant of the vascular function assessment PLM, we have identified a novel peripheral vascular assessment method that is more easily performed than PLM, which, by not evoking potentially confounding central hemodynamic responses, may be more useful clinically.
- A translational cellular model to study the impact of high-frequency oscillatory ventilation on human epithelial cell function
Traditionally, large-animal models are used to analyze the impact of clinical ventilators on lung cellular function. In our dual-chamber model, we interface high-frequency oscillatory ventilation (HFOV) directly with airway cells to study the effects of HFOV independently and combined with hyperoxia. Therefore, it is possible to study the preclinical impact of interventional factors without the high cost of animal models, thus reducing staff, time, as well as animal sparing.
VIEWPOINTS | Aging and Exercise
- Commentaries on Viewpoint: A time for exercise: the exercise windowTHE OPTIMAL EXERCISE TIMING "WINDOW" DEPENDS ON THE OUTCOMECOMMENTARY ON VIEWPOINT: A TIME FOR EXERCISE: THE EXERCISE WINDOWCOMMENTARY ON VIEWPOINT: A TIME FOR EXERCISE: THE EXERCISE WINDOWCOMMENTARY ON VIEWPOINT: A TIME FOR EXERCISE: THE EXERCISE WINDOWCOMMENTARY ON VIEWPOINT: A TIME FOR EXERCISE: THE EXERCISE WINDOWEXERCISE STRATEGIES TO IMPROVE POSTPRANDIAL METABOLIC CONTROL: MORE TO BE DONECOMMENTARY ON VIEWPOINT: A TIME FOR EXERCISE: THE EXERCISE WINDOWDOES THE "EXERCISE WINDOW" WORK IN TYPE 1 DIABETES?COMMENTARY ON VIEWPOINT: A TIME FOR EXERCISE: THE EXERCISE WINDOW
- Commentaries on Viewpoint: "Tighter fit" theory—physiologists explain why "higher altitude" and jugular occlusion are unlikely to reduce risks for sports concussion and brain injuriesFROM MONRO AND KELLIE TO MOUNTAINS AND CONCUSSION; THE SCIENCE OF SLOSHEXPLANATION OF BRAIN PHYSIOLOGY TO ENHANCE UNDERSTANDING OF THE "TIGHTER FIT" THEORYCOMMENTARY ON VIEWPOINT: "TIGHTER FIT" THEORY—PHYSIOLOGISTS EXPLAIN WHY "HIGHER ALTITUDE" AND JUGULAR OCCLUSION ARE UNLIKELY TO REDUCE RISKS FOR SPORTS CONCUSSION AND BRAIN INJURIESCOMMENTARY ON VIEWPOINT: "TIGHTER FIT" THEORY—PHYSIOLOGISTS EXPLAIN WHY "HIGHER ALTITUDE" AND JUGULAR OCCLUSION ARE UNLIKELY TO REDUCE RISKS FOR SPORTS CONCUSSION AND BRAIN INJURIESALL'S SWELL WITH THE BRAIN; ON THE SIGNIFICANCE OF BLOOD-BRAIN BARRIER DISRUPTION IN HYPOXIA

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A little bit about us and our ethos
We began as a takeaway serving the residents of Cambridge with Indian food prepared true to traditional Indian recipes. During this time, we were lucky enough to win several local accolades and also be a finalist in the BBC Food and Farming Awards.
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Administrative Law involves compliance with and challenges to rules, regulations, and orders of local, state, and federal government departments. Administrative law attorneys may represent clients before agencies like the workers compensation appeals boards, school board disciplinary hearings and federal agencies like the Federal Communications Commission. Administrative attorneys help negotiate the bureaucracy when interacting with the government to do things as varied as receiving a license or permit or preparing and presenting a defense to disciplinary or enforcement actions.
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Administrative Law Lawyers In Yorkville Illinois


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Country Style Fried Skillet Potatoes
Recipe by Kittencalrecipezazz
If possible use a cast-iron skillet for this but any skillet will do, also use only shortening for this. Cooking time is only estimated depending on the size you cut the potatoes, adjust all seasonings to taste. Make certain that you the cooked cubed potatoes are cold before using in this recipe!
Top Review by Lisa D.
I was in a hurry to make breakfast for 9 people. I didn't read that the potatoes had to be cooked. I also love onions so I modified this recipe a bit. In a cast iron skillet I heated up some oil and dropped in 1 whole onion finely chopped. While the onion was cooking on med-low heat, I cubed about 8 med potatoes, added seasoned salt, paprika, black pepper, garlic powder and about 1 tablespoon oil which helps spices coat and stick to the potatoes. Then I dropped the potatoes into the sautéing onions turned up the heat to med-high and let them cook uncovered, stirring occasionally until tender. I opted to chop 2 small sweet peppers for color and flavor. They paired well with scrambled eggs and polish sausage (or breakfast sausage can be substituted, country gravy with sausage or bacon or ham as well). All I can say is the pot was scraped clean. Thanks for the recipe. I will try it with cooked potatoes next time around.
See Discussion:6 Reviews
Ingredients Nutrition
- 1⁄3 cup Crisco shortening
- 5 large potatoes (cooked, peeled or unpeeled, cubed into about 1/2-inch or larger)
- seasoning salt (or use white salt)
- black pepper
- 1⁄2 teaspoon garlic powder
- 1⁄2 teaspoon paprika
Directions See How It's Made
- In a large cast-iron skillet heat the shortening over medium-high heat.
- Add in the cubed potatoes and cook stirring until the potatoes are golden brown.
- Season with seasoned salt, black pepper, garlic and paprika.
- Serve hot.
- Delicious!


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File Photo** * STEVE MARTIN IS A FIRST-TIME DAD Funnyman STEVE MARTIN has become a first-time father at the age of 67, according to a U.S. report. The Father of the Bride star and his wife Anne Stringfield welcomed the baby in December (12) but managed to keep their happy news under wraps until now. A source tells the New York Post gossip column Page Six, "They've had a baby, and how they kept it a secret nobody knows. Steve's very private. They are thrilled. They worked hard to have the baby." Martin married his second wife Stringfield in 2007 at a surprise ceremony where celebrity guests including Tom Hanks and Diane Keaton arrived expecting a party. (PAW/WNWCPS/ZN)** Steve Martin The 2010 Library Lions Benefit held at the New York Public Library Where: New York City, United States When: 01 Nov 2010 (1 Picture)
File Photo
Photo credit: WENN
View All: File Photo** * STEVE MARTIN IS...
Could Hasselhoff's popular former franchise make its way back into the spotlight?
Critically-acclaimed series 'The Handmaid's Tale' took home two accolades on the night.
The Rolling Stones star has thanked fans for their support following the news.


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Since party season is coming into full swing very soon & many of you host on game days, it seemed the perfect time to share this easy appetizer recipe. It's a Copycat Chili's Queso Dip and packs a lot of satisfying flavor. It would be the perfect recipe for your Football Sunday gathering, or any festive casual party. Serve regular queso dip as well if you have non-meat eaters in your crowd. Everyone will be happy.
Serve the Chili Queso Dip along with tortilla chips, crusty bread, crackers or even use it as a sauce if you like.
Making the Copycat Chili's Queso Dip Recipe
Making this Chili's Queso Dip copy cat recipe couldn't be much easier. Just cut up the Velveeta cheese, and add everything to a pot and stir until it is hot and melted. That's all there is to it.
- 16 oz Velveeta
- ¾ cup Milk
- ½ tsp Cayenne Pepper (optional, if you like it spicy)
- 15 oz Canned Chili (No Beans)
- 2 tsp Chili Powder
- 2 tsp Lime Juice
- ½ tsp Cumin
- Cut the Velveeta into cubes.
- Heat all ingredients in pan over medium heat stirring frequently.
- Serve with tortilla chips


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Release Date: February 12, 2014 (2D theaters and IMAX)
Studio: Columbia Pictures (Sony), MGM
Director: Jose Padilha
Screenwriter: Josh Zetumer, Nick Schenk
Starring: Joel Kinnaman, Gary Oldman, Michael Keaton, Samuel L. Jackson, Abbie Cornish, Jackie Earle Haley, Michael K. Williams, Jay Baruchel, Jennifer Ehle, Marianne Jean-Baptiste
Genre: Action, Adventure, Sci-Fi, Thriller
MPAA Rating: PG-13 (for intense sequences of action including frenetic gun violence throughout, brief strong language, sensuality and some drug material)
Official Website: RoboCop.com
Plot Summary: In "RoboCop," the year is 2028 and multinational conglomerate OmniCorp is at the center of robot technology. Their drones are winning American wars around the globe and now they want to bring this technology to the home front. Alex Murphy (Kinnaman) is a loving husband, father and good cop doing his best to stem the tide of crime and corruption in Detroit. After he is critically injured in the line of duty, OmniCorp utilizes their remarkable science of robotics to save Alex's life. He returns to the streets of his beloved city with amazing new abilities, but with issues a regular man has never had to face before.
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The Thrive Center will be presenting at the Society for Research on Adolescence (SRA) in Baltimore, Maryland. See below for more information on presentation information and for links to calendar entries.
Poster Discussion Symposium: An Anchor in the Storm: Religion and Spirituality as Protective Factors Among At-Risk and/or Ethnic Minority Youth
Discussant: Pamela King, Fuller Theological Seminary
Chair: Meredith Hope, University of Nebraska-Lincoln
Presentation Time: Thursday, March 31 (10:15am to 11:45am)
Presentation Location: Hilton Baltimore, Holiday 1
God-Contingent Self-Worth Moderates the Effects of Religiousness on Regulation in At-Risk Adolescents and Emerging Adults
Presenters: Sarah Schnitker, Fuller Theological Seminary; Benjamin Houltberg, Fuller Graduate School of Psychology; Nathaniel Fernandez, Fuller Theological Seminary; Nanyamka Redmond, Fuller Theological Seminary
Religious Support, Discrimination and Psychiatric Disorder of Black Adolescents in the National Survey of American Life Supplement
Presenters: Yasmin Cole-Lewis, University of Michigan-Ann Arbor; Meredith Hope, University of Nebraska-Lincoln; Shervin Assari, University of Michigan-Ann Arbor; Cleopatra Caldwell, University of Michigan
Religious Behavior and Spirituality on Rural and Low Socioeconomic Status Adolescentsâ Sociopolitical Values
Presenters: Rebecca Olson, West Virginia University; Lauren Alvis, West Virginia University; Aaron Metzger, West Virginia University
The Role of Religiosity as a Protective Factor: Religious Beliefs Moderate Exposure to Violence for African American Adolescents
Presenter: Donna Shannon, Fordham University; Loyola University Maryland
The Impact of Religiosity on the Delinquency of Maltreated Youth
Presenter: Jill Comerford Schreiber, Southern Illinois University Edwardsville
Paper Discussion Symposium: Faith as fertile ground?: Exploring the social and cultural context of religious and spiritual development
Chair: Pamela King, Fuller Theological Seminary
Discussant: Chris Boyatzis, Bucknell University
Presentation Time: Thursday, March 31 (12:15pm to 1:45pm)
Presentation Location: Hilton Baltimore, Carroll AB
Tridimensional group identity among Muslim-American adolescents: Associations with family and psychological functioning
Presenters: Madiha Tasheen, University of Maryland, Baltimore County; Charissa Cheah, University of Maryland, Baltimore County
The identity formative characteristics of significant teachers as described by religious and non-religious Israeli students
Presenter: Elli Schachter, Bar Ilan University, Israel;
I was ready to wear hijab to show everyone I am a proud Muslimâ:Development of religious practice in Muslim-American adolescents
Presenters: Kathleen Cain, Gettysburg College; Isabella Schiro, Boston College
Exploring the social ecology of highly spiritual youth among diverse religious traditions from around the globe
Presenters: Pamela King, Fuller Theological Seminary; Jonathan Weber, Fuller Theological Seminary; Mona Abo-Zena, Brown University;
Paper Discussion Symposium: Examining the relationship between adolescent spirituality, religiousness and regulation
Discussant: Amanda Morris, Oklahoma State University
Chair: Benjamin Houltberg, Pamela King, Fuller Graduate School of Psychology
Presentation Time: Friday, April 1 (10:15am to 11:45am)
Presentation Location: Hilton Baltimore, Douglass
The Role of Patience and Emotion Regulation Strategies in Explaining the Link Between Spiritual Transcendence and Youth Outcomes
Presenters: Benjamin Houltberg, Fuller Graduate School of Psychology; Nanyamka Redmond, Fuller Theological Seminary; Sarah Schnitker, Fuller Theological Seminary
Regulation Moderates the Relation between Religiosity and Antisocial Behavior in Muslim Indonesian Adolescents
Presenters: Doran French, Purdue University; Urip Purwono, Padjadjaran University; Nancy Eisenberg, Arizona State University; Sharon Christ, Purdue University
Transcending time and place: Character, contribution, and intentional self regulation in the promotion of positive development
Presenters: Richard Lerner, Tufts University; Jacqueline Lerner, Boston College; Milena Batanova, Tufts University; Kristina Callina, Tufts University; Andrea Ettekal, Tufts University; Kaitlyn Ferris, Institute for Applied Research in Youth Development – Tufts University; Lacey Hilliard, Tufts University; Sara Johnson, Tufts University; Jun Wang, Tufts University; Michelle Weiner, Boston College
Roundtable: The Nature and Function of Natural Mentoring in Adolescent Development
Presentation Time: Friday, April 1 (3:45pm to 5:15pm)
Presentation Location: Hilton Baltimore, Holiday 3
Moderator: Peter Samuelson, The Thrive Foundation for Youth
Panelist: Jean Rhodes, University of Massachusetts- Boston
Panelist: Kent Pekel, Search Institute
Panelist: Pamela King, Fuller Theological Seminary
Panelist: Michael Garringer, MENTOR


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Kingston: Confidential (Tony Price: Confidential Book 3)
Thirty years of social work at the Silver Birch housing project in Scarborough come to an abrupt end for Tony Price after he rescues a woman and child from an armed dope fiend. Burnt out and vodka-soaked, he is forced into retirement. During the hot summer of 2016 he moves with his wife, Brenda, to ... More info →
Sioux Lookout: Confidential (Tony Price: Confidential Book 2)
It's 1994 and eight years have passed since the horrific events at the Silver Birch Housing Project, recorded in Scarborough: Confidential. At the urging of his girlfriend Brenda, vodka soaked social worker Tony Price has decided to take a vacation in Sioux Lookout, Ontario. Far from home, Tony st... More info →
Scarborough: Confidential
It's November 1987 in Scarborough, Ontario, and someone – or something – is killing off Tony Price's clients in the Silver Birch housing project. The community, already dysfunctional and violent, is terrified. Tony, a chain smoking, vodka soaked burnout, sets out to find the killer. Badgered... More info →


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Pottery Operatives
- Recruiter
- The Best Connection Group Ltd
- Location
- Stoke-on-Trent, Stoke-on-Trent
- Salary
- £8.00
- Posted
- 30 Apr 2017
- Closes
- 04 May 2017
We are currently seeking Pottery Operatives to work for a local company based in Hanley. Our client requires bench casters, hand dippers and hand painters for a local ceramics company. The ideal candidates will of wokred within a similar role and the desire to gain a permanent position. The hours of work will be on a continental shift working three days on, 3 days off, 3 nights on and 3 nights off Additional Benefits & Requirements 28 days Paid Annual Leave pro-rata for PAYE (inclusive of statutory holiday) The Best Connection Employment Group Limited was formed in 1991. The company has a network of 80+ branches throughout the UK, from which specialise in the supply of temporary labour to the industrial, HGV, warehouse and distribution sectors.


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Men's Sports
Women's Sports
Men's Sports
Women's Sports
Oct. 1, 2006
SANTA CLARA, Calif. - The No. 10 ranked University of San Diego men's soccer team (7-3-0, 2-2-0 WCC) was defeated 2-1 by the No. 15 ranked Santa Clara University Broncos (6-3-2, 2-1-0 WCC) Sunday afternoon at Buck Shaw Stadium.
San Diego out shot the Broncos 13-8 in the match with six attempts in the first half alone. However, the Broncos were first to score early in the fifth minute. Forward Brian Martin took a shot from the far side of the field which was deflected by Torero goalkeeper Lance Friesz. Forward Keith Devey rebounded the deflection and took a shot past Friesz for a 1-0 lead.
The Broncos followed that shot with another goal in the 43rd minute. Martin intercepted a clearance by the Torero defense firing off a quick shot low into the net past Friesz for a 2-0 lead at the end of the first half.
In the second half, San Diego came out shooting recording seven shots. In the 56th minute, forward Ryan Guy from outside the penalty box passed the ball to midfielder Kevin Meissner who fired off a shot from 14 yards and past Bronco goalkeeper Joseph Buttitta cutting the lead 2-1. However, San Diego was unable to tie the match.
The Toreros return home to San Diego where they will take on No. 18 ranked University of San Francisco on Sunday, Oct. 8 at 2:00 p.m. at Torero Stadium.
© Copyright 2017 West Coast Conference. All Rights Reserved.


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Principle #1: "Walk Your Own Path"
What is the right business for you to start?
In this principle we'll dive straight into into the different types of startups and the different routes that people take into entrepreneurship. We'll examine our motivations and get clear on our "good idea criteria". We'll explore what types of business we are each best positioned to start, we'll discuss the difference between startup projects and fully-fledged businesses, and we'll seek to demystify the entrepreneurial process.
There is no one way to build a business – choose your own path.
If you behave as if there is just one way to build a business, you will put a huge amount of pressure on yourself. The clearer you are about the most viable businesses for you, the more you will save yourself difficulty further down the line. Define success for yourself. Stay strong – it is hard to maintain your definitions of success in a world that is constantly bombarding you with other people's ideas for how things should be done.
What should you focus on at this stage?
- Figure out your motivations and set clear intentions for the coming months.
- Get honest with yourself about what type of business you are best positioned to start.
- Explore different startup journeys and types of businesses.
- Understand the difference between an entrepreneurial project and a business.
Core Concepts
Run towards something
You want to run towards something you care about rather than away from something you don't care about. There are many good reasons for starting a business, but escaping a negative current reality shouldn't be the only one…
Clarify your objectives
There are a few obvious reasons for wanting to start a business and most of us share the main ones.
What are your top 3?
- Money / Security?
- Purpose / Passion?
- Independence / Autonomy?
- Impact / Change?
- Skills / Challenge?
- Personal Growth?
Ensure you're up for the ride
Starting a business can be hard. The main reason for this is that you're trying to create something that doesn't exist and see it impact the world in a positive way. The more you can be clear on the sacrifices you'll make and the challenges you'll encounter on this journey, the more you'll know what you're letting yourself in for and be able to prepare yourself.
Avoid the trap of never starting
The fear of spending +5 years and lots of money building something that doesn't work is the main reason most people don't start. A few things to bear in mind:
1) it has never been cheaper to get something started
2) you don't have to make a five-year commitment in order to begin experimenting with ideas and projects
3) the only way to really know if something might work is to move from thinking to doing.
Define success for yourself
The more you look into startups, the more you'll feel the pressure to build the next runaway success. Are you building a rocketship (that will require lots of funding), a lifestyle business (I want to become a digital nomad), or a reliability business (I need it to pay me within 3 months)?
Embrace unpredictable outcomes
Your motivations, your definition of success, and the opportunities that you can take advantage of will all change as you start turning your ideas into realities. Successful entrepreneurs accept uncertainty, act on what information they have access to today and trust their ability to create whilst reacting to unfolding events.
Invest in your future self
The decisions you take today will impact who you become over the coming years. You are not the person you are going to be in 5 years time. Don't beat yourself up for not being an entrepreneur today, the only way to become one is to keep taking one step after another along this path.
Create surplus time and money
Find a way to create a surplus of time or money (ideally both!) to give you the breathing space to build. The no#1 cause of startup failure is running out of cash. The longer the runway the more likely you are to find the way that works.
Tactics here include:
- keeping your day job to fund your startup
- negotiating down to a 3 or 4-day week
- finding regular freelance work
Choose the right founding story for you
There is no one way to leave employment and start a business. Some people go all-in, quit their jobs, and live off savings or raise early-stage investment to keep them going whilst they build. Others start their business from the safety of their jobs and work evenings and weekends until they have reached certain key milestones. And others still go part-time, take a sabbatical or do freelance work to stay afloat whilst building. What works is what works for you.
Partner up
It is a lot harder to build a business solo. Business partners are there to pick you up when you're down and to share the successes when they come. The power of two people obsessing about a problem is much greater than simply 1 + 1. However, you can't simply shop for a business partner – you have to build an authentic and trusting relationship over time. Start side-projects with different people by all means, but commit to a formal co-founder relationship with more preparation and lots of clear expectation setting.
Distinguish between projects and businesses
Startups can take years to turn into businesses. However, successful startup projects can be launched in a weekend. You will feel the pressure to build a business and you will beat yourself up that your idea doesn't look anything like one. Relax about building a business and focus on launching a successful startup project. If version 1 is successful you may decide to undertake the hard work of turning it into a business. But first, focus on the project.
Avoid the job trap
At the beginning of your entrepreneurial journey you may feel like you have 10 jobs that you have to do at the same time – all of which are poorly paid (or not paid at all!) and none of which you can delegate. You can't go on holiday and you can't switch off. Whether or not you want to be at the helm forever, in order to avoid creating a job that you can't escape from, you want to be building towards a business that can operate without you.
Start where you are
The test for a good startup idea for you is going to be determined by Who You Are (location, passions, interests, resources), What You Know (existing skills, industry knowledge, macro/micro understanding of trends or concepts) and Who You Know (strong relationships, membership of communities, access to networks).
Your Questions
Join The Tribe Forum for Q&A on the Startup Paths principle.
Popular Threads:
- How do you set up a social enterprise?
- How do I figure out whether I even want to start a business? (coming shortly)
- What different startup types and startup journeys are there? (coming shortly)
- Why is it dangerous to focus on billion dollar businesses?
Have a question that hasn't been answered yet?
Jump into the forum and ask away (just click "New Topic" in the top-right of the screen. Write your question as the Topic title, with your context / explanation as the Description).
Tools & Resources
>>> View the full Startup Tribe Toolkit.
Hello Tools:
Concepts and Frameworks
– Effectuation – A thinking framework that serves entrepreneurs in starting businesses, providing a way to control a future that is inherently unpredictable.
– Bird-in-hand – The first principle of Effectuation (also known as "start with your means"). Ask yourself: Who are you, what do you know, and whom do you know? Then, imagine possibilities that originate from your means.
– The E-Myth – This is quite a seminal book on entrepreneurship that argues that most entrepreneurs work in their businesses rather than on them and – through doing so – create jobs for themselves that they can't escape from.
– Linchpin: Are You Indispensable? How to drive your career and create a remarkable future – Seth Godin's call to action: whether you're building a business or not, the only way to build a career on your own terms is to be a linchpin.
– Anything You Want by Derek Sivers – 40 lessons for a new kind of entrepreneur. There are no rules for building a business: "When you make a company, you make a utopia. It's where you design your perfect world." Awesome little book.
Articles, Videos & Podcasts
– The Idea Maze
– The Ultimate Guide for Becoming an Idea Machine


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CoverGirl is now the first accessible makeup brand to embrace gender equality by announcing makeup artist and social media phenomenon James Charles as its ambassador. The line already has international popstar Katy Perry on its team and now CoverGirl counts on James to spread a groundbreaking message that anyone can be fearlessly express themselves. According to a recent interview with Fashionista he shared that the massive appeal of the brand was one of the main reasons he accepted the offer to represent CoverGirl and share his inspirational work as a male makeup artist and digital personality. We'll soon get to see James' TV commercial and ads but we really look forward seeing him collaborating on his own line along the brand.
THE SECRETS OUT.. so beyond excited to finally announce that I am the new face of #COVERGIRL and the first ever coverBOY. 😱 I am so thankful and excited and cannot wait to show you all what we have in store. Make sure you go check out @covergirl on Instagram for more info! AND YES I know I have lipstick on my teeth 😬😂 it was a looonnnnggg day.


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Tibet and Tigers
When the Indian government pioneered tiger conservation by launching Project Tiger in 1973, no one could have dreamt that the fate of India's tigers was likely to rest in Tibet. On the Roof of the World, Tibet had been a closed country for centuries. Then, in the early 1950s the Chinese Communist government sent troops to take over Tibet; China had long claimed it was part of its territory, despite its inability to rule it. Faced with Chinese power the Tibetans were helpless, and the rest of the world only expressed its concern.
Concern was particularly strong in neighbouring India, which had had ties with Tibet, and found it no longer had a buffer against China. A diplomatic battle arose over the validity of India's frontier with Tibet, which stretches 3,000 km from Kashmir to the frontier with Myanmar. It erupted into war in 1962, in which the Chinese army quickly defeated the Indian forces. The dispute has simmered ever since, despite diplomatic negotiations.
In 1959, the Dalai Lama, the revered spiritual leader of Tibet, fled to exile in India, and thousands of Tibetans followed him, settling in India and Nepal, close to the frontier with Tibet. That rugged frontier through the highest mountains in the world was impossible to police effectively, and exiled Tibetans maintained contact with those who had stayed. To the annoyance of the Chinese, the Dalai Lama, living close to the frontier, retained his authority over most Tibetans. That annoyance is now threatening India's tigers as the Chinese seek to combat the Dalai Lama's efforts to end the Tibetan trade.
In the mid-1980s, suspicion arose that India's tigers were being poached to provide bones for traditional Chinese medicine. Vivid proof came in 1993 when 400 kg of bones were found in a part of Delhi where Tibetans had settled. They were destined for China via Tibet. In following years more seizures of bones occurred both in India and Nepal. Curiously, skins, which had long been smuggled out of India to many parts of the world, were often discarded by the poachers when they collected the bones.
With the turn of the century, however, seizures showed that skins were once more in demand, although it was not clear exactly where they were going. Leopards were now also under pressure, with up to 10 skins being seized for every tiger skin. Hundreds of otter skins were also found. Truckloads of professionally-treated skins have been found en route for Nepal and points near the Indian frontier from which they were being shipped to Tibet. Similar seizures by Chinese police occurred in Tibet itself of shipments enroute to China. Signatures of Tibetans known to be active in India, but evading arrest, were on the skins.
In 2002 the British-based NGO Environmental Investigation Agency (EIA) published a report which revealed the extent of the trade (Cat News 41 p.21). But it was in 2005 that photographs of Tibetans draped in tiger and leopard skins at horse fairs showed the full extent (Cat News 43, p.12), and that when India was already gripped in a crisis over missing tigers.
The Dalai Lama had several times deplored Tibetan involvement in wildlife trade since the bone seizure in 1993, but without much apparent effect. After the dramatic photos he addressed a religious meeting in India, which was attended by thousands of Tibetans, many from Tibet, calling on them to "never use, sell, or buy wild animals, their products or derivatives". Tibetans started to burn tiger and leopard skins. This alarmed the Chinese authorities who saw the power the Dalai Lama still held over his people in Tibet.
Although the Chinese had announced collaboration with western NGOS to publish posters condemning the illegal trade, they sent troops in to stop the burning. Nevertheless, reports indicate that skin burning still occurs.
And now two Chinese government authorities, the Information Centre and United Front Department, have ordered TV presenters in Amdo, where skin burning started, to wear animal skins when presenting the news, and provided funds for them to buy skins. It appears to be an attempt to combat the Dalai Lama's influence.
China has proclaimed that it is cracking down on illegal trade, but now seems to be acting in a manner that could encourage it for wider political reasons. This could turn tigers and leopards into pawns, and threaten the majority of the world's last tigers, which are in the Indian subcontinent.
Peter Jackson
A Wild-to-Wild Translocation of Cheetahs from Private Farmland to a Protected Area in Zimbabwe (1994-2005) by G. Purchase, G. Vhurumuku and D. Purchase
In Zimbabwe, the legal status of the cheetah (Acinonyx jubatus) is that of a specially protected species (Parks and Wildlife Act 1996), but on the ground the cheetah is often regarded as a problem animal. Since the early 1980's reports of cheetahs killing cattle on private ranches increased. It is thought in hindsight that this increase in cheetah reports was due to the eradication of lion and spotted hyaena on private land, the increase in game populations as many farmers switched from cattle to game, and a series of drought years. Conversely, in protected areas, cheetah numbers appeared low. .
Alarm over Tiger Data by Prerna Singh Bindra
The first phase of this all-India estimate was to indicate the presence and absence of tigers in reserves, national parks, sanctuaries and even outside protected areas; and the presence, abundance or lack there of prey species and habitat quality. This first phase was completed in most cases by January 2006. Four months on, none of the 17 states has sent a report to the Wildlife Institute of India. In fact, at a meeting of Chief Wildlife Wardens from across India, pressure was put on the states to submit their initial findings, but to no avail.
Determination of Prey Hair in Faeces of Free-ranging Namibian Cheetahs with a Simple Method by B. Wachter, O. Jauernig and U. Breitenmoser
Namibia is thought to host the largest population of freeranging cheetahs Acinonyx jubatus and the majority of this population inhabits commercial farmland (Morsbach 1987). Some farmers consider that cheetahs prey on both livestock and wild herbivores that are valuable for trophy hunting, and this perceived offtake has generated conflict leading to the indiscriminate elimination of cheetahs from some farms (Marker et al. 1996). To help assess the economic cost of cheetahs on commercial farmland, information on the proportion of different prey species in their diet is required.
The Lion in Gabon: Historical Records and Notes on Current Status by P. Henschel
Little is known about the historical distribution of lions (Panthera leo) in Gabon, and until recently it was unclear if lions still existed in the equatorial country. In this article, I provide a summary of available historical reports from many sources, including some records not previously published. I also collate recent (since 1995) reports of lions in Gabon including fresh evidence that the species might still be extant in the Batéké Plateau region in south-eastern Gabon.
Update on the Iberian Lynx ex-situ Conservation Program by A. Vargas, F. Martínez, J. Bergara, L. D. Klink, J. M. Rodríguez, D. Rodriguez and A. Rivas
In the evening of 23 March 2006, Iberian lynx (Lynx pardinus) female Saliega gave birth to two healthy cubs. This is her second litter. The cubs were born in the El Acebuche Conservation Breeding Centre, where she gave last year birth to the first litter of the Critically Endangered Iberian lynx ever born in captivity (see Cat News 42).
African Lion Conservation Strategies by K. Nowell, L. Hunter and H. Bauer
Sightings of snow leopards Uncia uncia in the wild are rare. This is because snow leopards occur in low numbers and are very elusive.Snow leopards may be sparsely distributed, but they may not, however, be very elusive in the world's highest park, Sagarmatha (Mt. Everest) National Park in Nepal.
Reintroduction of the Chinese Tiger by U. Breitenmoser, R. Tilson and P. Nyhus
On 17–18 December 2005, the Department of Wildlife Conservation of the State Forestry Administration (SFA) of the P.R. China, supported by the non-governmental organisation Save China's Tigers, organised a workshop on the rehabilitation and reintroduction of the South China Tiger (Panthera tigris amoyensis). The South China tiger is listed as Critically Endangered in the IUCN Red List. There may be some tigers left in the wild, but there is a good possibility the in situ population is extinct. The tiger is not only an ecological umbrella species, but has an outstanding cultural significance, and the Chinese are dedicated to saving it.
Range Size and Den Use of Gordon's Wild Cat in the Emirate of Sharjah, United Arab Emirates by P. Phelan and A. Sliwa
The first radio-tracking study on two Gordon's wildcats Felis silvestris gordoni (Harrison 1968) revealed several results important for the conservation of the wildcat in the region (Phelan & Sliwa 2005).
The Leopard Controversy in South Africa: Common Cat or Conservation Concern by B. Daly and Y. Friedmann
Fundamental to the effective management and conservation of any species is a reasonable estimation of population sizes, distribution and trends. Much of this information is unknown for the leopard Panthera pardus, and leopards have been referred to, by eminent carnivore researchers Luke Hunter and Guy Balme, as the world's most persecuted big cat. Despite the fact that accurate knowledge of the status of this species is lacking, decisions regarding its future are frequently taken and the species continues to be hunted, persecuted and forced out of its natural territories.
Jaguar Study in Paraguay by R. T. McBride Jr.
The Gran Chaco of Paraguay contains the largest population of arid land jaguars Panthera onca left in the Americas. The Chaco varies in rainfall from west to east from 250 mm annually to 1,200 mm annually with corresponding habitat transition zones. Land clearing in eastern Paraguay serves as a grim reminder of how rapidly the cumulative effects of fragmentation can result in the deforestation of an entire region. Jaguars in eastern Paraguay have been reduced to isolated populations that are heavily persecuted and approaching extinction.
A Comparison of Detector Dogs, Hair Snares, Cameras, and Scent Stations for Detection of Bobcats by R. Harrison
Adequate monitoring and detection of populations of small and medium-sized felids has been difficult to achieve with traditional methods. However, new detection methods have been developed. To compare survey methods for bobcats Lynx rufus, I examined the rate of detection, cost, and time required for automatic cameras, hair snares, scent stations, and a detector dog trained to find bobcat feces (scats). This dog produced nearly ten times the number of bobcat detections as the other methods combined. Although the detector dog was the most expensive method and, depending upon weather and number of scats required, took more field time than the other methods, its use required only one visit to each survey site. Use of detector dogs has the potential to achieve detection rates consistently high enough to provide useful indices for the population monitoring of bobcats. Detector dogs may also be used in a laboratory setting to identify bobcat scats within a sample set collected from the field.
Fishing Cat on India's East Coast by S. Kolipaka
The mangrove forests spreading over the 240 km2 of Coringa sanctuary on the coast of Andhra Pradesh state are one of the only surviving fishing cat Prionailurs viverrinus habitats of any considerable size on the east coast of India.
First Camera Trap Photos of the Andean Cat in the Sajama National Park and Natural Area Integrated Management, Bolivia by T. Barbry and G. Gallardo
The Sajama National Park is one of the 8 Bolivian protected areas located in the potential range of distribution of Oreailurus jacobita, the Andean cat. It is also the second National Park in Bolivia where the species presence is officially confirmed. The last indication of the presence of the Andean cat in Sajama National Park was a skin found in 2002. The Andean cat is classified in the category "Endangered" in the 2004 IUCN Red list and in the Appendix I of the CITES convention and it is therefore considered to be facing a high risk of extinction in the wild.
Andean Cat in Mendoza, Argentina - Furthest South and at Lowest Elevation Ever Recorded by L. E. Sorli, F. D. MArtnez, U. Lardelli and S. Brandi
The Andean cat Oreailurus jacobita is one of the least-known and perhaps the least common of the South American felids. Previously it has been found only in arid and semi-arid habitats at altitudes between 3,000 and 5,000 m above sea level in the Andes of Perú, Bolivia, Chile and Argentina. This new record extends the known distribution of the Andean cat by at least 500 km, and to an altitude previously not considered in evaluations of the distribution and conservation status of the species.
The Tigrilladas in Colombia by E. Payan and L. A. Trujillo
The jaguar Panthera onca and the tigrillos, - the ocelot Leopardus pardalis, the margay L. wiedi and the oncilla L. tigrinus - are the four spotted cat species indigenous to the Colombian Amazon basin. The cat skin boom of the 1960s and 1970s is well known, but details of how these skins were produced remain obscure. The tigrilladas is the name is given to the hunting missions that used to go after jaguars and tigrillos to cater for this fashion craze. Here we detail how these operated and discuss the significant implications for conservation.


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Documentary Director
James Newton Documentary Director
If those who proselytise on behalf of the Big Society have slightest bit of common sense, they will ring the BBC this morning, order several thousand copies of last night film Boy Cheerleaders and post them to every sceptic of plans for the regeneration of civic society with whom they are familiar. James Newton's superb and compelling documentary
You might make all sorts of assumptions about the sorts of boys who'd join a cheerleading team, especially if it was the country's only boys' cheerleading team but this clever, compassionate film blasted many of them to bits
For all the boys' exuberance – and their third place gained at the UK championships – it was a melancholy tale. You could see the hope – not of further dancing success, but of more distant, unarticulated dreams. If there's anything more guileless than a prepubescent boy in front of the camera, I really don't want to see it. It's beautiful and it tends to break your heart.