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1000W CO2 Metal and Non-Metal Lasr Cutting Machine
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- Model NO.: GY-1218K
- Drive Type: AC Servo Drive
- Control: CNC
- Laser Type: CO2
- Certification: GS, SGS
- Trademark: Great Year Laser
- Origin: Guangzhou, China
- Power: High Power
- Engraving Machine Type: CNC Engraving Machine
- Current: AC
- Usage: Woodworking
- Condition: New
- Specification: CE, SGS
- HS Code: 84561000
Product Description
1) Travelling table and stationary gantry design, to provide a rigid and stable platform and save the space
2) Unique CNC control system with the excellent developing capacity of HMI, CNC and PLC, following the most advanced process. The control system is supplied laser die-board process database, machine operation function, laser operation function, remote diagnose function and so on.
3) Special cutting head design which is powerful for die board cutting and easy to replace the lens.
4) New programming software multiple file formats supporting, and machining process customization.
5) Capable to cut different slit width in one drawing.
6) Configured with a three directions optical design, available for different customer environments. The machine is enclosed optical path and positive pressure dust removal, to ensure the long life of the lens.
Applicable materials:
It is widely used in Die board Cutting, PVC plastic board , steel plate, aluminum alloy, stainless steel and non-metal sheet.etc.
Applicable industry:
It is widely use in Die Cutting industry, advertising signs production, the production of metal sheet,
Technical index:
Working area 1200*1800mm
Cutting thickness 0.1-25mm
Cutting Speed 0.5m-0.8m/min
Knife meet width 0.3-3mm(adjustable)
Laser power 1000W
Resolution 4000dpi
Location precision <0.02mm
The smallest characters formed Chinese:2×2mm,letter:1×1mm
Power Supply AC220V±10%,50Hz
Gross Power <3600W
Working temperature 0°C~45°C
Working humidity 5-95% (Free of condensed water)
Cooling way Industry Water cooling
Graphic file format Supported PLT,CDR,AI,DWG,DXF,DST,BMP,JPEG,TIFF,GIF,PCX,TGA etc.
1. What kinds of laser machine do you have?
For industry purpose, there are many different laser sources for different laser application!
1)40w-150w CO2 Laser (S, D, E series)
Engraving and Cutting Non metallic material like Acrylic, Plastic, Wood, MDF, Paper, Fabric, Textile, Leather, Marble, Ceramic etc.
2)Mixed CO2 Laser Cutting Machine 150w 200w 300w (CS/CM series)
Cutting Thicker Acrylic, MDF, Wood and Thin Steel 2mm
3)Fast Flow CO2 Laser Cutting Machine1000w 1500w 2000w (H series)
Cutting Thicker Metal and Wood MDF Acrylic
4)Fiber Laser Cutting Machine 500w 1000w 2000w (CYM series)
Excellent Cutting Different Metal in different thickness
5)10w--50w Fiber laser, 50w-100w YAG laser (DP series, FLM series)
Engraving and Marking any Metal and some non metal (ABS plastic)
Such as Marking production date, company logo, serial no. bar code, 2D code on the object surface.
6)100w 150w 275w CO2 Galvo Laser Marking Machine (GYRF series)
Marking wood, leather, Jeans, Garments, Fabric, Acrylic (light guide plate)
2. Which machine is good for Garments/Cloth/Fabric/Textiles cutting?
S series, D series is suitable,
Most of customer will choose model GY-1490D 80W!
And refer to some added function model
With Auto feeding function TF and TK Series
Three Heads Laser Machine ST series,
Four Heads Laser Machine F series
3. Can I Engrave metals with a CO2 Laser?
Answer is No!
But Co2 laser can Engrave Anodized metal and some metal with Ceramic coatings, plastic coatings or paints!
4. How do I learn to operate lasers?
1) User manual, CD with video will along with machine for training you how to install, how to use, and how to maintains,
2) Moreover, Skype, Team viewer online service is available for you,
3) Free training will offer you on our factory, Engineer is available to offer international service!
4) Local agent service available is extending all over the world!


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About FUMPC
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Worship Services
8:00 am Contemporary Service
Join in a casual service with a blend of contemporary Christian music, praise choruses, and traditional music. The desire is for you to experience God and leave refreshed and ready to live out your faith!
10:30 am Traditional Service
A service rooted in the liturgy and hymns of a traditional church is what you will find in this more formal worship service. In this setting you will be filled with God's message and your life enriched because of your faith encounter!
Fellowship Time
9:00 am
Join in the fellowship of snacks, coffee and juice in our Fellowship Hall. This is a chance to get to know others or to reconnect with friends.
Sunday School
9:15 am
We offer classes for all ages! There are multiple classes that study a variety of Christian materials and subjects.
We offer nursery care for children ages 4 and under during both services and Sunday school.
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Embodying Women's Work
- Edition: 1st
- Format: Paperback
- Copyright: 09/01/2008
- Publisher: Open University Press
Note: Not guaranteed to come with supplemental materials (access cards, study guides, lab manuals, CDs, etc.)
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What is the relationship between women's reproductive bodies and women's productive work? How does women's potential for maternity affect women's workplace opportunity? How far can women 'choose' and maintain their own embodied boundaries in relation to work and working practices? This fascinating and topical book evaluates the growing debate on gender, women's bodies, and work. Through the lens of the body - and from a feminist perspective - Gatrell considers women's work from two angles, the first conceptualizing the labour of maternity as women's work, the second exploring the dynamics between women's bodies and employment.The author suggests that maternity constitutes women's work, with some women 'expected' to produce children, while others are criticised for giving birth. She calls for the re-conceptualization of pregnancy, birth and breastfeeding as forms of labour asserting that mothers are required to perform particular forms of body work in order to comply with ideals of 'good' mothering and norms of the workplace. The book observes that these are conflicting requirements, which place irreconcilable demands on women and constrain women's choice.At the heart ofEmbodying Women's Workis the idea that women's bodies are central to gendered power relations, and remain a negotiated site of power between men and women within late modern society. The book considers women's bodies in the context of different forms of paid work, discussing how far women remain at an economic disadvantage in comparison with male workers.Embodying Women's Workis of key interest for students and academics of sociology, social welfare and women's studies.


text: Sorting type: Most visited Most visited Alphabetical | Characters described as "mutants", having distinctly unnatural traits/abilities resulting from DNA and genetic alterations. Pages in category "Mutants" Deinonycanis Indominus rex Mr. DNA Pachysaurolophus Stegospinus Retrieved from "http://spielberg.wikia.com/wiki/Category:Mutants?oldid=4776" Ad blocker interference detected! Wikia is a free-to-use site that makes money from advertising. We have a modified experience for viewers using ad blockers Wikia is not accessible if you've made further modifications. Remove the custom ad blocker rule(s) and the page will load as expected. Categories: Monsters Characters Hybrids Add category Cancel Save


text: "Uh-Oh!"This article is a stub. Why don't you help Brendan Barnepedia by expanding it? Boris (Caliou's dad) is the father of the well-known grounded child named Cailou. Boris, himself, isn't very well-known in the Go!Animate community. Retrieved from "http://brendan-barney.wikia.com/wiki/Boris?oldid=565" Ad blocker interference detected! Wikia is a free-to-use site that makes money from advertising. We have a modified experience for viewers using ad blockers Wikia is not accessible if you've made further modifications. Remove the custom ad blocker rule(s) and the page will load as expected. Categories: GoAnimate Characters


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Great Massage Services
The Advantages of Deep Tissue Massage
Deep tissue massage is a type of rubdown that concentrates of deep layers of muscles. In most cases, this type of massage is regarded as an effective treatment method. It is true deep tissue massage can heal different types of ailments. Firm stroke and deep finger pressure are used when doing this kind of massage. If you want the rubdown to be done properly, an expert is required. For the best professional Leduc deep tissue massage therapist patients can search locally or online.
You can accrue a lot of benefits if you opt for deep tissue massage. To begin with, deep tissue massage can help ease chronic pain. Deep tissue massage is believed to be a cost-effective method of easing pain. You cannot compare it with other common ways of relieving pain. This massage is an effective way of curbing inflammation, which is a main cause of chronic pain. proper deep tissue massage can help alleviate muscle tension. When the body is massaged, the tight muscle tissues are loosened.
Secondly, deep tissue massage helps improve blood pressure. Since deep tissue rubdown can alleviate stress, then it can have a positive impact on blood pressure. If carried out by a specialist, deep tissue massage can help trigger the production of serotonin, which is a hormone that helps bring happiness.
Thirdly, continued Leduc Deep Tissue Massage helps heal scars in the body tissue. This is because it improves lymphatic circulation in the body. This kind of massage is good for people who are nursing scars from surgical operations. But always remember it has to be done by a specialist in the field.
Again, deep tissue massage can enable you ease stress and anxiety. Deep tissue massage can be helpful to you if at all you have chronic stress. It also helps people with rigid shoulders, tight muscles and tension headaches. When done by a professional, this kind of massage can make you to forget all what troubles you and get a peace of mind.
Also, this type of massage can make movement easier. When a certain part of the body gets injured and eventually heals, a scar is formed. Scars also form inside the body. Such deep parts of the body can be healed through deep massage. The rubdown helps in promoting movement or motion without pain.
Studies show that people who embrace deep tissue massage have low chances of getting high blood pressure and cardiovascular diseases. Deep tissue rubdown can help promote flow of blood to all parts of the body. If blood can circulate freely to all parts of the body, then it means oxygen is properly distributed. So, there are very slim chances of developing heart diseases and hypertension. Always ensure the Leduc Therapeutic Massage is done by a specialist in the field.


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Primary Automotive Mechanic Duties
The dual-automotive-powered DELIGHT OF PAY 'N PAK of 1970 was impressed by the success of the 1969 7-Litre Class hydroplane RECORD-7, which was the primary Limited hydro to run a warmth at over one hundred miles per hour. I suppose the problem is- there are so MANY of them,they reproduce quickly in great numbers and they are hungry. The door may not be saved correctly. This may additionally lead to a twist being introduced into the door. Textual content is accessible underneath the Inventive Commons Attribution-ShareAlike License ; additional phrases may apply. Through the use of this web site, you comply with the Phrases of Use and Privacy Policy Wikipedia® is a registered trademark of the Wikimedia Basis, Inc. , a non-revenue organization. Listed here are a pair more stable recommendations which are recognized to be reliable and specs-compliant for those within the engineering field.
At Goodwood Pageant of Speed, Honda UK hosted the biggest motoring showdown since the heady F1 days of Senna vs Prost. Bear in mind, you wish to be the man, the go-to man. Automobiles are a commodity. You may get one anywhere. However there's just one you. You're the value add, you are the motive someone's going to do a deal. Period. It's very rare now a days when it is just in regards to the automobile and it is by no means simply in regards to the deal. That is a brand new one, but it would possibly work, (nothing, it seems, works 100% … Read More


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Flamepelt is a ginger tom with black on his face, tail, and ear mostly. Makes his appearance in Wood and Sorrel (regular fanfic)
Has blue eyes
Rank: Warrior
History Edit
Flamepelt is not a major character, but is mention in chapter two, when Brightsparrow's father, Deepstripe (DC) gets hit by a Twoleg monster. Flamepelt was one of the few to carry his body to camp.
Family and Important Cats Edit
Mother: UNKNOWN
Father: UNKNOWN
Siblings: Stonemouth
Other relatives: Brightsparrow, Moonwillow, Deepstripe (DC), Thrushtalon
Mentor: Woodflame
Apprentice: Firepaw (soon to be Firefang)


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Sally Romas is a popular girl who is a senior and who doesn't usually give chances to boys to talk to her or have a relationship with her. She's a cheerleader.
Grayson Dolan is a popular guy who is senior and who plays around with girls, he never had a serious relationship with a girl. He's in the football team.
0fficMovementGirls Jul 25, 2016
um are there any requests open to be in this? or no im sorry im new:|


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It's important to acknowledge and celebrate the big events in our lives. We celebrate important milestones in life, such as marriages, funerals, baptisms, and the birth of a child. These are particular 'rites of passage' and deserve special attention.
But there are other just as significant important occasions that tend to get overlooked – such as the transition of a woman from maiden to mother. In days gone by, this event was greeted with great celebration, and I think there's value in restoring some of the reverence associated with this important milestone.
As a doula, and drawing on my facilitation background I can help you arrange and facilitate Blessing Ways and Baby Showers. These events are opportunities to 'fill a woman's cup' – to esteem, honour and support her to help her transition through pregnancy and birth and adjusts to becoming a mother.
Similarly, I can help with arranging and/or facilitating Naming Days to formally welcome and introduce children to their community – their extended family and friends.


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Burp posted an update 1 month, 2 weeks ago
Yesterday driving back home from work I noticed a police car, on the window it had a lgbt rainbow sticker on it in support of the lgbt community. I think that this is an extremely provocative and political statement and one what should not be on a back of a police car. Having a gay sticker on a back of a police car is basically saying if you are against this kind of thing then we will arrest you.
@burp active 3 weeks, 4 days ago
So Donald Trump wants to go to war with North Korea and potentially sacrifice millions of soldiers lives to stop north Korea (which is what North korea wants anyway) from developing nuclear weapons?I think that it is all well and good that Donald Trump is concerned about North Korea having nuclear weapons but in my opinion Donald Trump should […] View


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CelebStyle Smarts
CelebStyle gurus, have you missed me? I'm back to deliver more fun-filled celebrity style questions. This week we witnessed a slew of Hollywood gals clad in looks ranging from sexy cool to fresh and clean to sportif to mod. I hope you were paying attention. Let's find out . . .
CelebStyle Smarts
What color flats did Michelle Williams wear with her white jeans outfit on Labor Day weekend?


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Budget $200 USD
I need an mobile application!
Skills: Android, C Programming, C++ Programming, Game Development, Mobile App Development
See more: project need, project management mobile application, mobile project application, project application mobile, sms mobile project application, project vbnet mobile application, project sms mobile, sms application mobile phone, project application java mobile, gps application mobile
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We investigated the possibility of using a pharmacologic agent to modulate viral gene expression in order to target radiotherapy to tumor tissue. In a murine xenograft model, we had previously shown targeting of [125I]2'-fluoro-2'-deoxy-beta-D-5-iodouracilarabinofuranoside ([125I]FIAU) to tumors engineered to express the Epstein-Barr virus (EBV)-thymidine kinase (TK). Here we extend those results to targeting of a therapeutic radiopharmaceutical [131I]FIAU to slow or stop tumor growth or to achieve tumor regression. These outcomes were achieved in xenografts with tumors that constitutively expressed the EBV-TK, as well as with naturally-infected EBV tumor cell lines. Burkitt's lymphoma and gastric carcinoma required activation of viral gene expression by pretreatment with bortezomib. Marked changes in tumor growth could also be achieved in naturally-infected Kaposi's sarcoma herpesvirus (KSHV) tumors following bortezomib activation. Bortezomib-induced enzyme-targeted radiation (BETR) therapy illustrates the possibility of pharmacologically modulating tumor gene expression to effect targeted radiotherapy.
Targeting of radiopharmaceuticals provides an important tool for the therapy of malignancy. Targeting tissue-specific surface antigens such as CD20 on B cells with radioimmunoconjugates has expanded the application of therapeutic radiation1,2. However, radioimmunoconjugates may be limited by the target level of expression, antibody affinity, or the physical characteristics of the antibody (that may impede delivery to large tumors or protected compartments) 3. Targeting metabolic pathways such as those involved in concentrating iodine in thyroid tissue is an alternative approach the more general application of which has been limited by the ability to identify appropriate tumor-specific pathways.
Epstein-Barr virus (EBV) is associated with various lymphomas and carcinomas. Kaposi's sarcoma herpesvirus (KSHV, HHV-8) is associated with sarcoma and lymphoma. The viral genome serves as a nearly tumor-specific target4. Thus virus-associated metabolic pathways approximate tumor-specific metabolic pathways. The ability to target radioisotopes to herpesvirus pathways has been demonstrated using vectors engineered with the herpes simplex 1 (HSV1) thymidine kinase (TK) gene to monitor gene expression in the gene therapy setting5,6. Direct application to virus-associated tumors has been limited by the virtual absence of expression of the TK in tumor cells.
We previously demonstrated that naturally occurring tumor cells harboring EBV could be imaged with a radiolabeled nucleoside analogue, if a pharmacologic inducer of the viral TK was utilized7. In the present investigation, we extend that observation to demonstrate that an inducing agent with a radiotherapeutic nucleoside analogue allows targeted therapy of virus harboring tumor cells in xenograft models.
To evaluate specificity with regard to the concentration of 2'-fluoro-2'-deoxy-beta-D-5-iodouracil-arabinofuranoside (FIAU) in tumor tissue, we used a human osteosarcoma cell line engineered to express the EBV-TK8. Tumor cells were engrafted on the flanks of SCID mice. After tumor was palpable, [125I]FIAU was administered intravenously and mice were sacrificed (Fig.1). Selective concentration of radioactivity in tumor was apparent by 2 hours and radioactivity levels in the tumor remained constant until the last time point at 96 hours, whereas levels in nontarget tissues decrease. In a parallel experiment carried out to later times, radioactivity in tumor was stable from 2 hours to the last time point at 4 days (not shown). The tumor to muscle ratio climbed from 4.6 at 2 h p.i. to peak at 205 at 24 h p.i. and fall to 114 at 96 h p.i. consistent with previous investigators' reports in a similar murine model with tumor constitutively expressing the HSV1-TK6.
To determine whether concentration of radioisotope in tumor tissue was adequate to achieve a therapeutic effect, mice were treated with [131I]FIAU or buffered saline (Fig. 2a). Control and TK tumors in mice injected with buffered saline, and control tumors in mice injected with [131I]FIAU showed similar growth curves, and of note, the 95% confidence intervals of the slopes of those growth curves (as determined by linear regression) overlapped. However, the growth slope of TK tumors in mice injected with [131I]FIAU flattened (i.e. the confidence interval for the slope of TK with [131I]FIAU in particular includes a zero slope estimate and does not overlap with the confidence intervals of the other growth curves). In separate experiments, increasing doses of [131I]FIAU were associated with increasing effects on tumor growth (Fig. 2b). When chimeric tumors were generated from admixtures of TK and control tumor cells, increasing percentages of TK-expressing tumor cells in the admixture were also associated with increasing effects on tumor growth (Fig. 2c).
Can a therapeutic effect be achieved in a naturally infected tumor? In previous studies we identified bortezomib as a potent inducer of lytic EBV infection7. In order to evaluate the specificity in naturally infected tumor tissue, EBV (+) Burkitt's lymphoma cells were engrafted SC on the flanks of SCID mice. After tumor was palpable, [125I]FIAU was administered intravenously 24 hr after bortezomib and mice were sacrificed. Selective concentration of radioactivity was apparent in these tumors (Table 1). Therefore, we proceeded with an evaluation of a therapeutic isotope. As above, mice with Burkitt's lymphoma xenografts received either buffer or bortezomib followed the next day by treatment with [131I]FIAU or no treatment. As can be seen in Fig. 3a, tumor growth curves in mice injected with buffer followed by [131I]FIAU were similar to tumor growth curves in mice injected with buffer alone. Bortezomib without [131I]FIAU slowed tumor growth. Bortezomib followed by [131I]FIAU stopped tumor growth (the 95% confidence interval overlapped 0 but did not overlap the 95% confidence intervals of the slopes of the growth curves associated with buffer alone or buffer with [131I]FIAU). In experiments with a second EBV(+) Burkitt's lymphoma cell line (Akata), parallel results were achieved (data not shown). Thus, bortezomib allowed targeting of [131I]FIAU with therapeutic effect.
Although EBV is associated with Burkitt's', AIDS-related, Hodgkin's lymphoma, NK and other lymphomas, the numerically most important associations are with nasopharyngeal cancer (~80,000 new cases/year) and approximately 10% of gastric carcinoma (~93,000 new cases/year)9-11. In order to determine whether the bortezomib-induction strategy might also be applicable to epithelial malignancies, we studied a transplantable human EBV-associated gastric cancer (KT) xenograft12. Following engraftment, mice were induced with bortezomib followed by [125I]FIAU and tumors were imaged with single photon emission computed tomography (SPECT) (Fig.4a). Tissue distribution studies showed selective concentration of [125I]FIAU in tumor, although the ratios in tumor to other tissues were not as dramatic as with the Burkitt's lines (Table 1). When induction was followed by [131I]FIAU, tumor growth slowed (Fig.3b).
Could the approach be extended to KSHV-associated tumors? We studied two primary effusion lymphoma (PEL) cell lines that harbor KSHV. In a SCID xenograft model, bortezomib allowed imaging of both BCBL1 and BC3 with [125I]FIAU (Fig.4b). Tissue distribution studies showed selective concentration in tumor tissue (Table 1), and when induction was followed by treatment with [131I]FIAU tumors growth slowed (Fig.3c).
The HSV1-TK has been used as a tool in gene therapy13. Even the notion that a viral TK might be used to target radiation therapy has been explored by others 14. Similarly, induction of the EBV-TK with a histone deacetylase inhibitor followed by treatment with ganciclovir has been reported to induce remissions in some patients15. Here, we model a new approach: bortezomib-induced enzyme targeting of radionuclide (BETR) therapy. We show that this BETR approach yields promising results in lymphoid and epithelial malignancies in murine xenografts of human tumors.
How do the doses administered in the murine model extrapolate to the clinical setting? Experience with 131I-labeled antibodies against lymphoma in patients demonstrates that clinical responses are achievable with 0.5 to 2 Gy to the tumor16. The biodistribution data presented in Fig. 1 allow estimates of the absorbed dose to tumor and vital organs, and suggests that the kidneys and red marrow are the dose limiting organs for [131I]FIAU. As detailed in the online supplement, it should be possible to deliver 0.5 to 2 Gy to a 1 gram tumor in a 70 kg patient with critical organ doses well below toxicity.
FIAU was previously investigated as an antiviral17. Chronic dosing of FIAU was associated with hepatic damage and in some cases fatality18-20. In those trials, treatment for less than four weeks with a cumulative dose less than 200 mg was not associated with either clinical or biochemical evidence of toxicity. Thus, the "no-effect dose" of FIAU might be conservatively estimated to be on the order of 0.1 mg/kg per administration. [124I]FIAU has been administered to patients for imaging without any adverse effect on hepatic function21. Extrapolating from our xenograft experiments, a radiotherapeutic effect is likely to be achieved at doses of FIAU that are orders of magnitude times less than the no-effect FIAU dose in humans.
BETR treatment results in concentration of FIAU in lymphoma and carcinoma xenograft models and impacts on tumor growth curves for each of the tumors studied (Fig. 3). However, in the lymphoma models, growth stops, whereas in the gastric carcinoma model growth only appears to be slowed. This difference likely reflects two phenomena. First, epithelial tumors are more resistant to radiation than lymphoid tumors. Second, the percentage of injected radioactivity per gram of tumor achieved in the lymphomas is greater than in the carcinoma (Table 1, Fig. 4). Optimization for human tumors will ultimately require further xenograft and clinical studies, but the ability to image EBV-TK activation directly in patients and thus assess the relevant pharmacokinetics of radiolabeled FIAU offers the promise that optimization can be rapid.
One concern with all 131I-labeled radiopharmaceuticals is deiodination. In the case of tositumomab, dehalogenases decouple the radioisotope from the antibody moiety, resulting in free, circulating 131I. In order to block this accumulation, standard procedure involves pretreatment of patients with thyroid protective agents (potassium iodide) beginning before drug administration and continuing until 2 weeks after administration. In comparison, biotransformation of FIAU is limited because of the high chemical and metabolic stability of the N-glycosyl linkage in pyrimidine nucleosides that contain the 2'-fluoro substituent in the arabinosyl ("up") configuration22. Studies in serum and whole blood over a 24 h period indicate excellent stability and low susceptibility to deiodination. FIAU is also cleared more rapidly from the plasma than tositumomab (3.9 versus 48 hours). Thus with less deiodination and more rapid clearance, it may be expected to have a better safety profile with respect to radiation exposure in normal tissues than agents already in the clinic.
BETR therapy also offers possible advantages over other lytic induction-suicide prodrug approaches. All lytic induction approaches are limited by the tendency of gammaherpesviruses to latency. When ganciclovir or a similar agent mediates cell killing, a therapeutic effect will likely require that a large fraction of tumor cells express viral enzymes. Although the phenomenon of bystander killing attributed to the exchange of phosphorylated nucleotides and nucleotide analogues between cells via gap junctions has been recognized23, such killing is limited. In the gene therapy setting attempts have been made to engineer increased expression of the connexin protein in the gene therapy vector so as to increase such killing24. However, this approach to increasing bystander killing is not readily applicable in approaches that do not involve gene therapy. Indeed, some of the therapeutic agents used to treat tumors may interfere with such bystander killing25. [131I]FIAU bystander killing is not limited by connexin expression or gap junctions but is a function of beta emissions with a maximum energy of 0.61 MeV that deposit 90% of their energy in a sphere of radius 0.7 mm26. This "cross-fire" effect is likely an important contributor to the efficacy of radioimmunotherapy in lymphoma27. "Cross-fire" with [131I]FIAU may be inferred from Fig. 2c where the tumor growth rate is substantially slowed when even 10% of tumor cells harbor the EBV-TK. Cell level dosimetry modeling is presented in the online supplementary material.
A second limitation of the lytic induction-suicide prodrug approaches is that ganciclovir-mediated killing is cell cycle dependent. As reported by several groups of investigators, activation of lytic infection in EBV and KSHV infected cells leads to cell cycle arrest28-30, thus likely compromising cell cycle-dependent tumor kill. In contrast, radiation effects are not similarly diminished by lytic induction.
BETR therapy may also offer advantages over radioimmunotherapeutic approaches. Internalization of radioimmunoconjugates may lead to degradation and release of free isotope with consequent loss of specificity. In contrast, we observed that following injection of FIAU, isotope is stably associated with EBV-TK expressing tumor (Fig.1a). Enzymatic phosphorylation and incorporation into DNA (as has been reported in HSV1-TK expressing cells 6) offers the possibility of achieving high concentrations in tumor tissue not limited by concentration gradients. Finally, both FIAU and bortezomib are small molecules and thus better tumor penetration would be anticipated in comparison with antibody conjugates. FIAU does not penetrate the blood-brain barrier but does reach brain tumors reflecting disruption of the blood brain barrier22. More broadly, the use of small molecules to activate tissue or tumor-specific metabolic pathways suggests the possibility that metabolic targeting of radiation may have applications beyond thyroid cancer.
Lymphoma cell lines were maintained in suspension culture in RPMI 1640 (Life Technologies, Gaithersburg, MD) with 10% fetal bovine serum, 100 units/mL penicillin, 100 Ag/mL streptomycin, and 100 mmol/L L-glutamine as previously described7. TK-143B and V143B cells are stably transfected lines derived from the human osteosarcoma (143B) cell line carrying either a plasmid expressing EBV-TK or a control vector (PCDNA3), as previously described8. These were maintained in DMEM (Life Technologies) supplemented with 10% fetal bovine serum (Gemini BioProducts, Calabasas, CA), 100 units/mL penicillin, 100 Ag/mL streptomycin, 2 mmol/L L-glutamine, and 400 Ag/mL G418 for selection. The KT transplantable EBV(+) gastric adenocarcinoma was passaged in SCID mice12.
Bortezomib was administered IV at 1.67 μg/gram. FIAU, and 2'-fluoro-2'-deoxyuracil-β-D-arabinofuranoside were obtained from Moravek Biochemicals (Brea, CA). [125I] and [131I]NaI were purchased from MP Biomedicals (Costa Mesa, CA). [125I]FIAU and [131I]FIAU was synthesized as previously described7. For imaging or treatment, FIAU was administered 24 hours after bortezomib. In each of the experiments described bortezomib was administered as a single dose.
Cultured cell lines were tested for mycoplasma and found to be negative. Cells (5 × 106) were resuspended in 200 μL Matrigel matrix (BD Biosciences, Bedford, MA) and injected SC in 6- to 7-week-old male severe combined immunodeficient mice. Caliper measurements of the longest perpendicular tumor diameters were performed every other day. Tumor volume was estimated according to the formula for a three dimensional ellipse: 4π/3 × (width/2)2 × (length/2). Treatment and imaging studies were performed when tumors reached a size of ~1 cm in diameter.
As previously described7, [125I]FIAU in PBS was injected into the tail vein, 3 to 4 mice were sacrificed at each indicated time point, organs were removed and weighed, and tissue radioactivity measured using an automated gamma counter. The percent injected dose per gram (%ID/g) of tissue was calculated by comparison with samples of a standard dilution of the initial dose.
As previously described7, imaging was done as an adjunct to the ex vivo biodistribution studies. The X-SPECT (Gamma Medica Instruments, Northridge, CA) has a γ-ray detector head dimension of 20.5 × 15 × 9 cm and a field of view of 120 × 125 mm. The high-resolution parallel hole collimator used has the following specifications: 1.22mm hole diameter, 0.20mm septa thickness, 25.4mm bore hole length. The detector material composed of NaI[Tl] has a pixel size of 2 × 2 × 6 mm. Mice were placed in a prone position on the parallel hole collimator and kept under anesthesia with isoflurane. Ten-minute high-resolution scans of each mouse were obtained. SPECT-CT was done using the above-mentioned γ-ray detector and the CT detector sequentially without removing the mouse from the gantry. Analysis of imaging data was with ImageJ v1.30 (NIH, Bethesda, MD) or AMIDE (A Medical Image Data Examiner) for SPECT-CT (free software provided by SourceForge).
Linear regression and curve fitting were undertaken carried using GraphPad Prism software version 5.00 for Windows, GraphPad Software, San Diego California USA, www.graphpad.com.
We thank Richard Wahl, S. Diane Hayward, Wen-Son Hsieh and Meir Shamay for suggestions, Susanne Bonekamp, Keng Fai Kwok and Jianhua Yu for reconstruction of imaging data, Sen Wang for assistance in the syntheses of [125I]FIAU and [131I]FIAU, Gilbert Green for assistance with murine imaging and therapy, and Sridhar Nimmagadda for assistance with mice experiments. This work was supported by grants from the US National Institutes of Health (NIH/NCI P50 CA96888, P01 CA113239 and U24 CA92871).
COMPETING INTERESTS STATEMENT The authors declare no competing financial interests.
PubMed Central Canada is a service of the Canadian Institutes of Health Research (CIHR) working in partnership with the National Research Council's national science library in cooperation with the National Center for Biotechnology Information at the U.S. National Library of Medicine(NCBI/NLM). It includes content provided to the PubMed Central International archive by participating publishers.


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Give it Up
#1 Sanaa
The Swoop List Series
Stephanie Perry Moore
When Sanaa wakes up for another day of school, she just can't seem to shake the feeling that the day is somehow…off. She makes it to school and she finds out exactly where here feelings of dread are coming from. She's been added to the "swoop list" and everyone in school is pointing and staring at her. What is this list? Where did it come from? And why is Sanaa #1 on the list?
Stephanie Perry Moore is a popular African American writer who writes in the adult, teen, and juvenile fiction genres. She is well known for her captivating fiction series, and The Swoop List is no exception. Over the course of five fast-paced and engaging books, the author takes a look at the cruel side of high school, where rumors take flight and are taken as fact, whether they're true or not. The series focuses on five girls from different backgrounds and social circles that suddenly have one very devastating thing in common: they are all on the "swoop list" that's being circulated around school. Over the course of the books, we learn about each individual girl from the other girls' perspective, giving you a well-rounded view of their actions and feelings throughout the ordeal. Are all of the girls as innocent as they appear or are they hiding something?
The Swoop List series is a great read for any teenagers that are looking for a dose of reality in their fiction.
Pamela Jessie
Woodlawn Branch Library
Friday, June 26, 2015
Teen Book Review: The Swoop List: Give It Up
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Tuesday, January 14, 2014
Rev. Hyperion 1976-2014
A friend and amazing spiritual teacher passed away today 14 January 2014 of a cardiac event. He was 38 years old.
Those in the Pagan community might have known him as Hyperion from his work with The Unnamed Path or his rootworker business where he was known as Dr. E.
I only spent time with him in person once, when he was visiting Houston and I was still living there. We dished and drank and bonded over a similar tattoo we both had. He told me my mohawk was adorable. After that, we interacted on Facebook here and there.
I never sought training in The Unnamed Path, but his writings and podcast were tremendously healing for me and continue to be a source of strength and comfort. I regret now that I never got to be his student in this life.
My thoughts are with his partner Clayton, his family, friends and the Brothers of The Unnamed Path.
May the Ancestors welcome him and may perpetual light shine on him forever.
You can read the write up at The Wild Hunt here.
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Naïve Bayes (HW1): Tips and Tricks Shannon Quinn
Git Basics – http://git-scm.com/docs/gittutorial http://git-scm.com/docs/gittutorial [Advanced] Cheat sheet – https://github.com/tiimgreen/github- cheat-sheet https://github.com/tiimgreen/github- cheat-sheet
Some useful Hadoop-isms Testing and setup – Excellent Hadoop 2.x setup and testing tutorial: http://www.highlyscalablesystems.com/3597/hadoo p-installation-tutorial-hadoop-2-x/ http://www.highlyscalablesystems.com/3597/hadoo p-installation-tutorial-hadoop-2-x/ You won't need to worry about setup! – On GACRC, I'm setting up the VMs – On AWS, Amazon handles it But the testing tips near the bottom are excellent – Putting files into HDFS – Reading existing content/results in HDFS – Submitting Hadoop jobs on the command line If you use AWS GUI, you won't need to worry about any of this
Some useful Hadoop-isms Counters – Initialize in main() / run() – Increment in mapper / reducer – Read in main() / run() – Example: http://diveintodata.org/2011/03/15/an- example-of-hadoop-mapreduce-counter/ http://diveintodata.org/2011/03/15/an- example-of-hadoop-mapreduce-counter/
Some useful Hadoop-isms Joins – Join values together that have the same key – Map-side Faster and more efficient Harder to implement—requires custom Partitioner and Comparator http://codingjunkie.net/mapside-joins/ – Reduce-side Easy to implement—shuffle step does the work for you! Less efficient as data is pushed to the network http://codingjunkie.net/mapreduce-reduce-joins/ MultipleInputs – Specify a specific mapper class for a specific input path – https://hadoop.apache.org/docs/current/api/org/apache/ hadoop/mapreduce/lib/input/MultipleInputs.html https://hadoop.apache.org/docs/current/api/org/apache/ hadoop/mapreduce/lib/input/MultipleInputs.html
Some useful Hadoop-isms setup() – Optional method override in Mapper / Reducer subclass – Executed before map() / reduce() – Useful for initializing variables…
Some useful Hadoop-isms DistributedCache – Read-only cache of information accessible by each node in the cluster – Very useful for broadcasting small amounts of read-only information – Tricky to implement – http://stackoverflow.com/questions/212 39722/hadoop-distributedcache-is- deprecated-what-is-the-preferred-api http://stackoverflow.com/questions/212 39722/hadoop-distributedcache-is- deprecated-what-is-the-preferred-api
WARNING!!! Hadoop 1.2.1 vs Hadoop 2.2.0 WARNING!!! Hadoop 1.2.1 vs Hadoop 2.2.0
A little MapReduce: NB Variables 1.|V| 2.|L| 3.Y=* 4.Y= y 5.Y= y, W=* 6.Y= y, W= w 1.Size of vocabulary (unique words) 2.Size of label space (unique labels) 3.Number of documents 4.Number of documents with label y 5.Number of words in a document with label y 6.Number of times w appears in a document with label y
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text: Servers, bartenders managers and the like will be coming together with their kitchen brethren at Menton's upcoming Industry Lunch. On Monday, June 26th from 12:00-2:00pm the Barbara Lynch favorite will be cracking bottles of High Life and pouring $3 shots of fernet for the hardworking women and men of the service industry. There are a couple lunch options, a two-course meal with a glass of wine for $35 and a three courser with two glasses of vino for $45. Call 617.737.0099 for more details or reserve a spot here.


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Via his terribly drawn interpretations of favourite fairy stories and marvelous literature, Arthur Rackham (1867�1939) continues to be an everlasting legend of the Victorian era's Golden Age of representation. Rackham took the printing advancements of the early 20th century extra than the other artist of his time, masterfully manipulating the most recent colour approaches. immediately a technical and creative genius, Rackham had few equals while it got here to using muted colour, atmosphere, and expressive lines.
This awesome assortment screens extra than eighty of Arthur Rackham's so much beguiling illustrations. those phantasmagoric renderings spring from such literary legends as Rip Van Winkle, A Midsummer Night's Dream, Alice's Adventures in Wonderland, Aesop's Fables, Puck of Pook's Hill, Peter Pan in Kensington Gardens, and A ask yourself Book. From the most lovable fairy to the main ugly goblin, Rackham's artwork captures the sweetness, innocence, and experience that perpetually stir the human center.
Read Online or Download Rackham's Fairies, Elves and Goblins: More than 80 Full-Color Illustrations PDF
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Additional info for Rackham's Fairies, Elves and Goblins: More than 80 Full-Color Illustrations
Production books within the usa guarantees compliance with strict environmental legislation and gets rid of the necessity for foreign freight delivery, an incredible contributor to international pollution. And printing on recycled paper is helping reduce our intake of timber, water and fossil fuels. The textual content ot Rackham's Fairies, Elves and Goblins was once published on paper made with 10% post-consumer waste, and the canopy was once revealed on paper made with 10% post-consumer waste. in keeping with Environmental Defense's Paper Calculator, through the use of this leading edge paper rather than traditional papers, we accomplished the next environmental merits: timber kept: 7 • Air Emissions eradicated: 622 kilos Water stored: 2,995 gallons • strong Waste eradicated: 182 kilos for additional information on our environmental practices, please stopover at us on-line at www. doverpublications. com/green Copyright Copyright � 2008 by means of Dover guides, Inc. textual content copyright � 2008 by way of Jeff A. Menges All rights reserved. Bibliographical observe This Dover variation, first released in 2008, is an unique compilation of illustrations from the subsequent works: Rip Van Winkle (published via William Heinemann, Ltd. , London, and Doubleday, web page & Co. , 1905); Puck of Pook's Hill (published via Doubleday, web page & Co, 1906); Alice's Adventures in Wonderland (published by means of William Heinemann, Ltd. , London, and Doubleday, web page & Co. , 1907; The Ingoldsby Legends: or Mirth and Marvels (published through J. M. Dent & Co. , London, and Doubleday, web page & Co. , 1907); A Midsummer-Night's Dream (published through William Heinemann, Ltd. , London, and Doubleday, web page & Co. , 1908); stories from Shakespeare (published through J. M. Dent & Co. , London, and E. P. Dutton & Co. , big apple, 1907); Undine (published by means of William Heinemann, Ltd. , London, and Doubleday, web page & Co. , 1909); Peter Pan in Kensington Gardens (published by means of Hodder & Stoughton, London, and Charles Scribner's Sons, manhattan, 1912); Aesop's Fables (published by way of William Heinemann, Ltd. , London, and Doubleday, web page & Co. , 1912); Arthur Rackham's publication of images (published by way of William Heinemann, Ltd. , London, and The Century Co. , long island, 1913); mom Goose. The outdated Nursery Rhymes (published by means of William Heinemann, Ltd. , London and manhattan, 1913); English Fairy stories (published via Macmillan corporation, London and big apple, 1918); a few British Ballads (published by means of Constable & Co. , 1918); Comus (published by way of William Heinemann, Ltd. , London, and Doubleday, web page & Co. , 1921); and A ask yourself ebook (published by way of Hodder & Stoughton, London, and George H. Doran Co. , 1922). a brand new creation has been especially ready for the current version. be aware: Caption punctuation varies in keeping with the unique resource. Library of Congress Cataloging-in-Publicalion info Rackham, Arthur, 1867–1939. Rackham's fairies, elves and goblins : greater than eighty full-color illustrations / chosen and edited through Jeff A. Menges. p. cm. 9780486133461 1. Rackham, Arthur, 1867–1939. 2. Fairies in paintings. I. Menges, Jeff A. II. name. NC978. S. R32A4 2008 741.


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4711 E ROCK WREN Road, Phoenix, Arizona
$1,4003 Beds2+ BathsContract Pending
$1,4003 Beds2+ BathsContract Pending
4711 E ROCK WREN Road, Phoenix, Arizona 85044 - Great location in center of Ahwatukee, two story 3bedroom 2.5bath. Newer carpet. Formal dinning room, big family room and a fireplace. All appliances + Soft water system and RO system included. Home security system and Surround sound system ready. Bi-weekly landscaping included Close to freeway, school, shopping and dinning. 2% Rental tax. Renter/Agent verify all information.
Listing Courtesy of ECLAT Real Estate
"I cannot speak more highly of Robert Joffe. He represented my wife and I on the sale of our house in Arcadia and the purchase of a new one. Not only does Robert know the Arcadia market better than any other agent I have met, but he also has integrity, which in today's world is a rare commodity. If I could give him six stars, I would do so."


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Director's Notes
Current Events
The Sanderson Orchestra will be performing on;
October 13th 2016 at 6pm in the SHS Auditorium for the NHS incuction
December 7 , 2016 in the SHS Auditorium for our winter concert.
March 7, 2017 for our MPA participation at NC State. (More details forthcoming)
May ?,2016 for our Spring concert. (details forthcoming)
What's Happening
SHS Orchestra is currently working to meet the October 13 committment for the NHS induction.
The Sanderson Orchestra class is offered in both non-Honors and Honors levels (Honors only offered if you qualify)
Please contact Mr. Bell if you have any questions about the Sanderson High School Orchestra


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- Adult Adventure
- Some Body Parts
- Tools and Tapers
- Accessories
- Straight Barbells
- Curved Barbells
- Replacement Parts
- 14k Gold Only
- Earlets & Tunnels
- Captive Bead Rings
- Segment & Seamless Rings
- Ear Plugs
- Genuine Diamond Jewelry
- Hide Your Piercing
- Organics
- Spirals & Claws
- Screwball Rings
- Circular Barbells
- Fixed Bead Rings
- Charms
14k Gold Only
Gold Rings
Diamond Piercing Jewelry & More
Gold Nostril Pieces
Gold Circulars & Spirals
Gold Straight BB's
Gold Curved BB's
Gold Labrets
14k Gold 6 Prong Curved Barbell$162.9914k Gold 6 Prong Curved Barbell is a beautifully ornamented and very sparkly jewelry piece ideal for navel piercings. The gem is large and shiny so it will dress up your piercing nicely. This is a truly eye-catching piece you can wear almost anytime, anywhere. Learn More
Genuine Diamond Prong Set Solitaire - Curved Barbell$298.99 As low as: $288.99Genuine Diamond Prong Set Solitaire - Curved Barbell is a stunning jewelry piece ideal for those who appreciate luxury. This classy navel jewelry piece will decorate your piercing with amazing sparkle of real diamonds. This is truly a one of a kind piece you will love to wear for special occasions. Learn More
14K Gold - Princess Cut - Nostril Screw or NoseBone$57.9914k Gold Princess Cut Nostril Screw or Nosebone is a gorgeous nostril jewelry piece you can wear in almost any situation. It is simple yet elegant, so it will make a great addition to your body jewelry collection. Learn More
14K Gold Small Flower Fixed Ring$113.99The 14k Gold Small Flower Fixed Ring is a cute way to dress your piercing. It has a sparkly flower decoration so it's very adorable and distinctive. You can choose the center gem color as well as the flower petal gem color to fully customize this piece according to your wishes. Learn More
14k Gold Prong Heart Nosebone$26.99The 14k Gold Prong Heart Nosebone is a cute nostril jewelry piece ideal for any situation. It has a special heart gem that will sure attract a lot of attention. This nose jewelry piece is both discreet and stylish at the same time. Learn More
14K Clear Gem Rose Gold Nose Bone$24.9914k Clear Gem Rose Gold Nose Bone is a very romantic jewelry piece made of Rose Gold. It is specially designed for nostril piercings so it will make an adorable addition to your jewelry collection. The gem is made to sit flat so it's really comfortable to wear. A truly amazing piece that will dress up your piercing to perfection! Learn More
14k Gold Double Oval Large Curved Barbell$220.99 As low as: $210.9914k Gold Double Oval Large Curved Barbell is a stylish jewelry piece ideal for navel piercings. This classy barbell has two sparkly gems that will sure attract attention to your piercing. This is a great jewelry piece that will give you a touch of elegance! Learn More
14K Gold Labret with Ball$64.99The 14k Gold – Labret with Ball is a simple yet elegant jewelry piece you can wear over and over again. This is a great choice for your piercings and it's made of all solid gold. Learn More
14K Gold - Captive Rings with Specialty Beads$31.9914K Gold - Captive Rings with Specialty Beads are elegant Captive Bead Rings with unique bead styles. The rings are made of solid, nickel-free gold. There are 24 different bead designs to choose from. Learn More
14K Gold - Gem Ball Ring$71.9914k Gold - Gem Ball Ring is a sparkly jewelry piece made to attract attention. The best of all: it can be used for almost any piercing type. This lovely ring will sure up your style and add some sparkle to your piercing. Learn More


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Involves advising business owners on start-up considerations and legal structure options -- such as sole proprietorships, partnerships, corporations, limited liability companies (LLCs), and non-profit organizations -- and handle the formation of new business entities and filing of all necessary documents (i.e. articles of incorporation). Major factors affecting how a business is organized may include the size and scope of the business, the sector and the country, limited liability, tax advantages, and disclosure and compliance requirements.
Frederick is a town in Brown County, South Dakota, United States. The population was 255 at the 2000 census. Home to the annual Frederick Finn Fest, the town is part of the Aberdeen Micropolitan Statistical Area.
Business Organizations Lawyers In Frederick South Dakota


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by Stanley Clark with Herschel Dixon
(Part three of our discussion with Cyrus A. Webb.)Part One of our Three-Part Series about Cyrus A. Webb and Conversations
Part Two of our Three-Part Series about Cyrus A. Webb and Conversations
On Friday, July 17, 2009, Cyrus A. Webb-The King of Conversations—will celebrate his 34th birthday. In the past 10 years of his life he has been recognized as an award-winning visual and literary artist, motivational speaker and the founder of one of the largest literary franchises in the United States. With all of his accomplishments he has worked hard to remain humble in the face of his success and careful not to let setbacks, negativity or the natural occurrences of life to distract him from his goals.
Of all the projects he has lent his name and abilities to, it seems that the Conversations brand with its radio and television shows, bi-monthly magazine, newspaper columns and most recently his book clubs has been the highlight of his life thus far.
Looking for a Book Club that literally gets you in touch with the author? Then "Conversations" is for you! Founded in November 2006, CONVERSATIONS has set a new standard for all literary organizations. We not only discuss books, but we get the opportunity to enjoy a conference call Q&A or physical visit with the author as well. Join our book club today! Admission is free. JOIN THE ADDICTION: Get hooked on books!
- Conversations Top 100 Adult Books of 2015
- Conversations' 25 Most Inspirational Books of 2015
- BOOK REVIEW: The Face That Changed It All by Beverly Johnson
- Conversations Book Club's Top 10 Fiction Summer Reads 2015
- Conversations Book Club's Top 10 summer nonfiction reads 2015
- BOOK REVIEW: One Righteous Man by Arthur Browne
- Conversations Book Club President Cyrus Webb interviewed, Sat. Feb. 21st
- Cyrus Webb Introduces "A.J. and the Talent Show"
- Conversations Book Club's Top 100 Books of 2014
- Conversations Summer Book Fair 2014: Mission Accomplished!
- Conversations Top 25 Summer Reads for Adults (2014)
- Conversations' Top 10 Summer Reads for Young Readers (2014)
- Conversations Announces April 2014 Book Selection: Poetic Meter and Random Prose
Sunday, July 5, 2009
INTERVIEW: "The King of Conversations Talks The Past, Present and Future" by Stanley Clark with Herschel Dixon
Posted by Cyrus Webb at 11:13 AM
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New Release Tuesday: The Von Bondies
My guilty pleasure of 2009 so far goes to Detroit rockers The Von Bondies
Yes, it's Tuesday again, so you know what that means: more new music. This week, I have chosen to focus my energy on The Von Bondies' new album, Love, Hate And Then There's You. Now I know what you're saying: "Their last album wasn't all that good." You're right, it wasn't. It had the theme song to Rescue Me on it, but it was pretty thin beyond that. Imagine my surprise when first popping in the Bondies' new album and being assaulted by the amazingly simple yet shockingly addictive rock riffs and echoing vocals of lead singer (and Jack White punching bag) Jason Stollsteimer.
The album isn't high art nor does it reinvent music. It's brutally honest and sincere, all while being tantalizingly simple. I'm kind of shocked I enjoy the album so much (considering I usually enjoy more artsy, out-there music), but I can't quite seem to put it down. Love, Hate is bolstered by the damn-near-perfect single "Pale Bride." It's an unfairly catchy song, displaying Stollsteimer's aching, desperate vocals backed by Christy Hunt's arena-rock-worthy guitar. Let the song enter your head once and it will take about a month for it to finally find it's way out -- it is that catchy. When I first heard the album, I had no clue what the single was. After hearing "Pale Bride," I had no doubt that it would be the first single off the album. The track is surrounded by other effortlessly fun rock songs, helping move the album along without any bumps in the road. "Only To Haunt You" is repetitive, bland, and lacking ingenuity -- but I can't get enough of it.
Only To Haunt You - The Von Bondies
It's refreshing to come across an album that makes listening to music this much fun. Don't get me wrong: I love Animal Collective's Merriweather Post Pavilion, but some of those songs can be dense. They go on for five or six minutes and leave me scratching my head. But they are art, and I recognize genius when I hear it. Even a band like Lemonade, who I adore, can produce some out-there music. So I put my hat in The Von Bondies' ring, and they don't disappoint by rewarding me with Love, Hate And Then There's You.
Love, Hate And Then There's You is out today on Shout Factory Records.
Also out today:
Heartless Bastards - The Mountain (Fat Possum)
Telefon Tel Aviv - Immolate Yourself (Bpitch Control)
The Pains of Being Pure At Heart - The Pains of Being Pure at Heart (Slumberland Records)
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Talk:Legitimacy of Chinese philosophy
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Australia's gift to Medicine
Merino Sheep came to be in the early 1800's as Australia was being settled by the British. Governor Mcather was given the task of breeding sheep that could withstand the harsh Australian climatic conditions. He set about mating a mixture of sheep from different parts of the world, with sheep from Great Britain. Finally, he came up with a crossbreed of British and Spanish that became the famous Australian Merino Sheep. Since that day, this Sheep has produced one of the finest quality wools the world has ever known.
Sheepzorb Disposable Dressings
Learn more about Disposable Wound Pads
Laundering Modifications
We have made some slight modifications to the required procedure for laundering Australian Medical Sheepskin, below is a copy of the updated laundering instructions in a word document as well as a power point presentation explaining the process. There will be an instructional video for laundering posted on our YouTube Channel soon; we will let you know once it is up but in the mean time please feel free to view Stephen's other short instructional and informational video's on the channel.
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Chair and Bed Pads


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Botanical Blooms!
If you're already hopping, then you've just come from the Talented Bruno Bertucci's Blog. If your just joining me, No Problem! Start here and follow the buttons below!
For my card today, I wanted to focus on the leafs of this stamp set. By now, everyone recognizes the flowers from this set, but have you given much attention to the leafs? Leafs dominate this stamp set and they are actually quite beautiful. I love the shape of them and the layered detail stamp that coordinates with each one.
The colours I used for this card are Mint Macaron, Pear Pizzazz, Old Olive, Crumb Cake, and Whisper White.
The detailed leaf of my card is the large, bold leaf from the set. I stamped it onto Whisper White cardstock with Mint Macaron, Pear Pizzazz, and Old Olive Ink. I applied each ink colour onto the actually stamp itself, with sponge daubers. First: Mint Macaron to the edges of the leaf. Second: Pear Pizzazz to the center, making sure to over lap the edges of the Mint Macaron ink. Third and Last: Old Olive to the center, making sure to blend it out into the Pear Pizzazz ink. Then I stamped it. Once it was dry, I stamped the detail lines in Old Olive.
I used the coordinating Botanical Building Framelits to cut the large leaf out of Crumb Cake cardstock. To add a little dimension to my card, I popped it up with some stampin' dimensionals and layered it on top of my stamped image.
On my Mint Macaron card base, I stamped the medium leaf in Mint Macaron ink, 2nd generation, (I stamped off first, before stamping it onto the base) and added a strip of washi tape from the Affectionately Yours Washi Tape Pack. My greeting was created with the Sunshine Sayings Bundle.
Thanks for hopping in, I hope you enjoyed my sample with the Botanical Blooms stamp set. Up Next, is the Talented Mike Funke's Blog. Enjoy the rest of the hop and happy creating!


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Listen to free music played by e11enb
Blip.fm is internet radio made social. It's easy to search for, play, and discover free music recommended by real people. Join today to create your own free station and start listening to @e11enb.
e11enb @DJelectriCITYevents: "@SoMuch: "Thanks! @jfgill: "Passion Pit ~ Tonight, Tonight""" (reblip)
e11enb @solid it's like you were sharing my computer for a second there as your blip came on while I was listening to this one.
e11enb Here's another, putting Eddie front and center.
Jul 14, 2011 at 3:49 pm via YouTube | AMAZON | ITUNES
e11enb My favorite part of this song is the vocals and I like these remixes that bring them out more.
Eddie Vedder – Trouble (Los Angeles '98) HD| play
Jul 12, 2011 at 6:43 pm via YouTube | AMAZON | ITUNES
e11enb Come on Feel the Illinoise, what a strange but wonderful little album you are.
Jul 12, 2011 at 1:33 pm via YouTube | AMAZON | ITUNES
Thom Yorke – Analyse| play
The Radio Dept. – This Time Around| play
e11enb I've had Eddie on the brain since seeing his show a couple weeks ago.
Eddie Vedder – Don't Be Shy| play
Jul 7, 2011 at 8:43 pm via YouTube | AMAZON | ITUNES
e11enb rb @SofiaFada you've just reminded me to stop at the liquor store on the way home, thanks! (reblip)
The National – All The Wine| play
Eddie Vedder – Better Days| play
Jul 7, 2011 at 3:19 pm via YouTube | AMAZON | ITUNES


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tours & activitiesNot sure what to do in Glasgow? Let us recommend you some activities.View More Tours
Travel GuidesHere are some itineraries for your reference!View All Posts
neighbourhoodsLearn more about the areas where our hotels are located.
Loch Ness, Glencoe and the Highlands Small Group Day Trip from Glasgow
Stirling Castle, Loch Lomond and Whisky Trail Small Group Day Trip from Glasgow
Private Outlander Day Tour from Glasgow
Loch Lomond and Glengoyne Whisky Distillery Half Day Tour from Glasgow
Ayrshire Coast Day Trip from Glasgow: Robert Burns Country and Culzean Country Park
Millennium Hotel Glasgow
Glasgow City Centre
The Tall Ship at Riverside
Glengoyne Distillery
Gallery of Modern Art


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Your email:
Connect to the iGov RSS Feed.
New EPG paper in Energy Policy:
The implications of Brexit for the electricity sector in Great Britain www.sciencedirect.com/science/… #ExeterEnergy
August 18, 2017 4:00 pm
EPG's Catherine Mitchell on @BBCr4today on role of energy efficiency on bills and innovation. Here from 2h50 in... www.bbc.co.uk/programmes/b08zz…
August 8, 2017 10:49 am
EPG's Richard Lowes quoted in Utility Week regarding the peak heat issue. twitter.com/UtilityWeek/status…
August 8, 2017 10:35 am
IGov is examining the level, type and speed of system change within GB and internationally; its drivers; how actors across energy systems are responding; and how this is shaping future energy systems. We are interested in how disruptive these changes are, and how best to capture the socio-economic and environmental benefits that are on offer.
© 2017 IGov


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Local and state police will search the school for explosives after a bomb threat was found written on a wall at the West Barnstable campus, reports say. The Hyannis Center will remain open.
Classes at Cape Cod Community College have been cancelled Monday due to a threat made to the campus.
Massachusetts State Police spokesperson David Procopio said the bomb squad, Troop D authorities, K-9 units, firefighters and local police officers will begin search the campus at sunrise.
Authorities said a written threat was found on campus property. Since the school was empty Sunday evening, a decision was made to wait for daylight to search.


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Sort of. The lines between fashion, art, architecture, film, interiors and every other creative medium are frequently blurred. The latest remix comes courtesy of Pierpaolo Piccioli and Maria Grazia Chiuri of Valentino. Their alliance with the Australian artist Esther Stewart resulted in an awe-inspiring, geometrically colour-blocked Fall '15 menswear collection. It reminded us of many spectacular partnerships past.
Louis Vuitton might be leading the way (Sprouse, Murakami, Buren etc.), but the YSL Mondrian holds a special place in history.


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This past weekend I checked out the event of an old acquaintance I knew from my work at San Francisco Women Against Rape (SFWAR), Eri Guajardo Johnson. I heard about the event from following her on Instagram, where I saw that she was pursuing healing, holistic work and talked a lot about unicorns. I hoped that in going I might be able to connect with her in-person, and learn from and be inspired by her work. I had reached out to a number of friends to attend with me at Qulture Collective, a queer community space in Oakland that I hadn't been to yet but had been wanting to check out, but they were all busy on Sunday afternoon. Admittedly, I was a little nervous going on my own- I felt a bit like the dorky kid who hoped to belong. Continue reading
Tag Archives: color
Favorites from my 2016 Art Journal
Coping with the 2nd Presidential Debate
Blue of Distance
Glitter and a Horned Hare: 'Tis the Season for Homemade Holiday Cards
SF Open Studios- Weekend 4
Last Saturday, with only a shoulder bag in tow, I hopped on my bike to cover some ground for SF Open Studios Weekend 4. The air was warm, especially for November, and I had hours to go until the studios closed for the day. It turned out going on the early side worked in my favor, because I got to spend time talking to the artists I visited before the turnouts increased. I'm always glad when I learn the story behind work (I guess that over letting 'the work speak for itself,' although they're not mutually exclusive). Continue reading


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NJ Homes for Sale
Real Estate Listings: Homes for Sale in New Jersey
2 Nottingham Rd
Livingston, NJ 07039
Special Offer
For SaleEstimate Mortgage » Check Your Credit Score »
Type:Single Family
Year Built:1962
Sq. Feet:4,754 sq. ft.
Source ID:68421817
Listed:177 days ago
2 Nottingham Rd
Livingston, NJ 07039
Type:Single Family
Year Built:1962
Sq. Feet:4,754 sq. ft.
Source ID:68421817
Listed:177 days ago
Published with Weichert on 02/23.
Updated 08/19.
Related listing information is deemed reliable but not guaranteed.
Fhyllis "Candy" C. Blanga
Weichert, REALTORS
Phone: 1-800-872-7653
Weichert, REALTORS
Phone: 1-800-839-1278
Home Description
Home Description
EXPANDED SCUTARI SPLIT IN COVENTRY NESTLED ON ALMOST AN ACRE OF LEVEL LANDSCAPED PROPRTY.THIS FINE HOME FEATURES 4 BRS(3 ON THE UPPER LVL and 1 ON THE LWR LVL) 5 FULL BA (1 FULL BA IN CABANA) GREAT RM , FRML SUNKEN DR W BI BUFFET, SLIDERS TO STONE PATIO and POOL.FAM RM OFF KIT, W WOOD BURNING FP and STONE HEARTH and SURROUND, OPENS TO GREAT ROOM, EIK W NWR APPLS, 2 DESK AREAS, EAT IN AREA W BI BANQUETTE SEATING, SIDE DR TO PATIO and SEP ACCESS POOL. LOWER LVL FEATRS: 1 BR, FULL BA, FAM RM W BUILT-IN CABS, GYM W WALKOUT TO POOL AREA ACCESS TO OVERSIZED 2 CAR GAR. FINISHED BASEMENT W LARGE REC ROOM W WET BAR, FULL NEWER BA, LAUNDRY and STORAGE. INGROUND FREE FORM POOL W WATERFALL, STONE DECKING , PROFESSIONALLY LANDSCAPED, WET BAR and PRIVACY GALORE. CABANA W 2 SHOWERS and 2 CHANGING AREAS and BATH.
Full Baths:5
Bedroom 1 Dimensions:14x12
Bedroom 2 Dimensions:15x11
Bedroom 3 Dimensions:16x15
Bedroom 4 Dimensions:19x12
Kitchen Dimensions:22x8
Dining Dimensions:29x12
Living Dimensions:34x15
Den Dimensions:24x14
Family Dimensions:16x14
Available Rooms:
- Family Room
- Living Room
- + View All+ View All- View Less
- Patio
- Dishwasher
- Refrigerator
- Water Softener
- Central Vacuum
- Smoke Detector
- Carbon Monoxide
- Wet Bar
- Sky Light(s)
- High Ceilings
- Heat Pump
- Forced Air
- Zoned
- Central Air
- + View All+ View All- View Less
Click on toggles to move map in desired direction.
This map is informational only. No representation is made or warranty given as to its accuracy or content. User assumes all risk of use.
NJ.com, MapQuest and their suppliers assume no responsibility for any loss or delay resulting from such use.
Real Estate Tools
Published with Weichert on 02/23.
Updated 08/19.
Related listing information is deemed reliable but not guaranteed.
Livingston, NJ Real Estate
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So this piece is going to be huge (well, huge for me)-- 16x20"... and for sure I don't want to spend precious hours smearing/smushing my precious pencils over such a large area, only to find I don't like the color scheme or, worse, find I can't do convincing faces on that scale... (The faces are… Continue reading Coloring crisis! + Catholic coloring page
Month: July 2016
Ave Maris Stella sketch, take 3
Yes, it seems like this is the only subject I draw... 🙂 The client who has commissioned this piece asked that Our Lady be standing, so voila! Playing with the idea of stone pillars & cutwork critters (fish, crab, starfish, jellyfish) at the top. 8"x11" Which version do you prefer, standing or sitting? (Older version… Continue reading Ave Maris Stella sketch, take 3


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Hamton's Prehistoric Ancestors is a one-time character and the ancestor of Hamton J. Pig . He appears in the episode A Ditch in Time . he was voiced by the late Don Messick .
Hamton's Prehistoric Ancestors is shown to resemble his descendants but a little huge, and not wearing clothes.
He first appeared doing laundry while Buster's Ancestor dragged a large carrot and Babs' Ancestor was cuting a giant carrot. When When Suddenly Plucky (thanks to Montana Max's prehistoric ancestor whacking him for being on his property) appeared and her and the other bow to him and Plucky was named the new leader of the group. When Plucky first tried to name the land Pluckyland, and the other prehistoric citizens hated the idea, but when he mistakenly named it Acme Acres. he and the others loved the idea. he appears again near the end when Plucky returns to the past and he and the other ancestors, toss their fruit and vegetables at him for being a lousy leader.


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Editor's note: This story is the third in a three-part series. First, The Spencer Magnet looked at buildings that have been dubbed "unsafe structures" in the City of Taylorsville. Last week's story explained the city's unsafe structure ordinance, including how it has been applied lately, and today, we'll present some of the plans in motion and visions for restoring Taylorsville.
City Commissioner Beverly Ingram has a vision for downtown Taylorsville and at last week's meeting, the commission voted to take some steps toward making that vision a reality.
Ingram, who owns a business on and lives on Main Street, has been a primary proponent of enforcing the city's unsafe structure ordinance.
(For the purpose of unsafe structures, Commissioner Nathan Nation steps aside from that role to keep the commission updated as the fire chief of the Taylorsville-Spencer County Fire Department. As such, Nation abstains from voting on unsafe structure issues to avoid a conflict of interest.)
Most recently, Ingram made a motion to move forward in the process of enforcing the unsafe structure ordinance on a property located at 57 Jefferson Street. That step could have included asking the property owner to demolish the building or notifying the property owner that the city would demolish the building and place a lien on the property.
However, Ingram's motion during the July 10 meeting failed for lack of a second.
Frustrated with the results, Ingram has focused her efforts on another route she believes will remedy some of the city's issues.
Ingram and Taylorsville Police Officer Kenneth Bledsoe recently attended a seminar on code enforcement and enforcing the ordinances the city has on the books.
Although the city doesn't have a set "code" to enforce, it could have a citation officer to cite those found in violation of certain city ordinances — in fact, the commission voted 5-0 last Tuesday evening to allow the Taylorsville Police Department to do just that. Bledsoe will now add citation officer to his list of duties.
Primarily, for now, citations will be handed out to those violating the city's nuisance ordinance, which sets regulations for lawn appearance, among other things.
The commission also voted to set in motion the plans for a historical overlay district to help preserve and maintain some of the city's history. That district has not been mapped out, nor have any regulations for buildings within the district been set, but last Tuesday's action means the city acknowledges it has historical areas worth preserving.
That motion passed 4-1 with only Commissioner Nation voting no. Nation said he wasn't against creating a historical overlay district, but would rather the city enforce the regulations it has now than add others onto the list.
Ingram has been working with Main Street Manager Gordon Deapen to develop the foundation of the historical district, and both seem to have similar visions for the future the city.
Ingram said she can remember stories her parents used to tell about the bustling city of Taylorsville.
"Downtown wasn't rich, but you could get anything you needed here," Ingram said, recalling tales of ice cream shops and gathering at the local post office.
Ingram said she would love to see the post office moved back downtown.
"It's such a good gathering place," she said.
"We have a great little downtown," she said. "It just needs some work."
Some of that work is currently going on in the form of the Phase II Main Street project, which is nearing completion. The sidewalks on Main Street from Jefferson to Main Cross have been redone to match the sidewalks from Phase I, which included Main Street from Main Cross to Washington.
Ingram said she hopes the Phase II project will start a domino effect and inspire business owners to spruce up their storefronts.
"It did last time," Ingram said, referring to Phase I. "We could be on the move again."
Ingram and Deapen are proponents of a historical overlay district in part to preserve Main Street and keep the city from having "missing teeth" — if the only option is to tear down a building, the hole it would leave is similar to a missing tooth in a smile.
Deapen said he would like to see buildings repaired and new retail businesses moving in.
"I don't think we want a Seven-Eleven just so we have something in there," he said. "We need to move forward with things that make sense."
Deapen said he's not in opposition to government offices or apartment-style city dwellings in the vacancies on Main Street, but thinks those things would make sense on the second level of buildings, with retail business on the main floor.
"Let's put private businesses in the storefronts and put government and apartments in the second story," he said.
While booming businesses on Main Street may be further in the future, both Ingram and Deapen encourage current property owners to take pride in their property.
"Ownership of property from Jefferson to Washington is a sacred trust," Deapen said. "It's history, a piece of culture. If you choose to own property on Main Street, you should commit to maintain it."
Ingram echoed that sentiment.
"It hurts me to see places falling apart," she said, noting that she has recently replaced the roof and HVAC system at her store. "It's not cheap, but if I couldn't do it, I'd get rid of it."
That thought should extend to property owners who rent out residential property as well, she said.
"Have respect for the human beings who may rent there."
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