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Colin Edwards RSV Mille R
Price - £ 7499.00
Stock Number - 63009682
Engine Capacity - 998cc
Current Mileage - 13200
Date Registered - 10/09/2003
Model Year - 2003
Colour - Black
Colin Edwards Replica Aprilia RSV Mille RNow here we do have a nice rare bike with 461 produced worldwide.
Aprilia produced the RSV Mille R Edwards Replica with a livery inspired by the Aprilia RS3 Cube MotoGP motorcycle riden by Colin Edwards.
The motorcycle came with a circuit kit, which included Akrapovic exhausts, a more pressurised airbox, an Eprom injection unit and 57mmm (instead of 51mmm) throttle bodies.
The Mille also featured a type of slipper clutch, which worked by using a vacuum on a closed throttle from the inlet manifold to give the effect of slipper clutch, but only on a closed throttle, whereas most modern examples use a ramp mechanism in the clutch basket.
When you sit on the Aprilia RSV1000 Mille the suspension barely compresses and you realize it's 100% sports motorcycle.
It's a delight on fast, smooth roads, tipping easily into corners and firing out with a pleasant balance of stability and maneuverability.
The Aprilia RSV1000 Mille has a compact 60 degree V-twin with a dry sump for extra rigidity and constant lubrication, even when wheelying. At low revs the power's beefy..
Dip into the midrange and it's really muscular and really gets the motorcycle shifting fast.
Top end power is truly immense!
Call us for a PCP Quote on this bike 0114 252 5454
Call us for a HP Quote on this bike 0114 252 5454
Other finance options are available, please call us for your personalised quote on 0114 252 5454
*Fees are already accounted for within the payments displayed and are also included within the total amount payable.
Finance available subject to status. Indemnities may be required. Other finance offers may be available but cannot be used in conjunction with this offer.
We work with a number of carefully selected credit providers who may be able to offer you finance for your purchase.
We are only able to offer finance products from these providers.
Why Buy From Us
We are so confident that you will be delighted with this bike when you see it, we will take it off sale for you for just £99 deposit.
We are more than happy to let you try any of our bikes before you buy. Please call us to arrange a test ride on 0114 252 5454.
Want a newer bike, or just fancy a change? We will make you a very competitive offer on your current bike.
From only £49.00
We will deliver from only £49.00 to anywhere on the UK mainland. So if you fall in love with any used bike we have in stock, there's nothing stopping you from giving us a call on 0114 252 5454
Secure the bike of your dreams with a small deposit, we can sort out the finance, delivery and arrange a convenient time to deliver your bike, no fuss, no hassle.
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While you were sleeping, the first round of the 2017 British Open teed shortly after 1:00 AM, but at 5Dimes you can bet golf live while in play.
World No. 3 Jordon Spieth cards a 5-under 65 in the first round of the Open Championship. He was a 12/1 favorite to win the famed Claret Jug. Spieth was bogeyless on the front nine and made birdies on 2, 8 and 9 to go out in three-under 31. He added birdies on 14 and 17 to close out at 65 and steal the clubhouse lead from Ian Poulter.
Fellow American Brooks Koepka closed out strong with an eagle on 17 to close at -5 as well.
Yet to tee off is 11/1 favorite Dustin Johnson. Click here for live leaderboard results.
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|Reviews for Nightmare
| purple scene chapter 1 . 6/17/2008
So beautiful.
I really love how you describe the scene, and the feelings of these three magnific characters. This precious end touched me. I like so much IchiHitsuKusa but is so hard to find, and your great work makes me happy.
Sorry for my bad english, Im a suffering spanish fan...
| mimic shalle chapter 1 . 3/23/2008
mah, mah, that was just whoa, it totally blew me away.
| handa chapter 1 . 3/22/2008
aalhfasd. Speechless.
That was just... yeah, whoa. XD
I'm going to go watch the AMV and probably wake me dad up with my happy sounds.
| Frozen-Void chapter 1 . 3/22/2008
aw SWEET i was listening to the music while reading i love their relationship


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World Heritage
Posted on September 14, 2014 at 3:14 pm | comment
A number of petitions have been lodged with the World Heritage Committee requesting that sites threatened by climate change be added to the List of World Heritage in Danger.
Human Rights
Posted on at 3:14 pm | comment
In order to contribute to the protection of the right of every person of present and future generations to live in an environment adequate to his or her health and well-being.
Climate Justice Fund
Posted on at 3:13 pm | comment
Climate justice addresses issues such as who is hurt, how are they hurt and who is responsible. It shifts our focus to the human impacts of climate change and responsibility for those impacts.
Introducing… The Carbon Levy Project
Posted on at 3:10 pm | comment
Loss and damage from climate change is happening: the Carbon Majors need to pay.
Posted on at 7:30 am | comment
Our work is focused on engagement in the ongoing international climate negotiations backed up by advocacy and work on the ground with the aim of ensuring REDD+ stays on track to become a force for positive change.


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Legendary Chevrolet Corvette C5-R Raises The Bar In 2004 Championship-winning factory team announces powerful upgrades for sixth season DETROIT - Fast on the heels of capturing a record-setting third manufacturers' championship in the American...
Legendary Chevrolet Corvette C5-R Raises The Bar In 2004
Championship-winning factory team announces powerful upgrades for sixth season
DETROIT - Fast on the heels of capturing a record-setting third manufacturers' championship in the American Le Mans Series, the General Motors Chevrolet Corvette Racing team is hard at work in developing an even stronger package for the upcoming 2004 season. Furthering its status as the most successful race car in the 50-year history of the marque, the Corvette C5-R will start next year with significant developments in tire technology, personnel, engineering and aerodynamics.
"Corvette proved once again why it is worthy of the title 'America's sports car icon'," said Harry Turner, group manager for road racing. "Racing is the crucible where Corvette's reputation was forged. The accomplishments of this team mean so much to Chevrolet and the millions of owners and enthusiasts worldwide. We plan on continuing that tradition in 2004."
The Corvette Racing program recently announced a new partnership with the Michelin Group. The manufacturer will provide technical assistance and full tire support for the Corvette C5-R in the American Le Mans Series and the 24 Hours of Le Mans endurance race. The team is currently undergoing another winter of rigorous development in preparation for the upcoming season.
"This championship season was another incredible chapter written in the rich history of the Corvette," said Doug Fehan, GM's program manager for Corvette Racing. "The competition challenged our position, but when the dust settled we were able to claim the title once again. This team has an amazing ability to overcome obstacles and that's how champions are made."
The works Corvette team recently announced the addition of drivers Olivier Beretta, Max Papis and Jan Magnussen to the Chevrolet family. Beretta, 34, will join Oliver Gavin in the #4 Corvette C5-R for the full season of the ALMS and the 24 Hours of Le Mans, bringing years of racing at the top levels of international competition, from Le Mans to Formula 1, to a driver roster already rich in talent. Papis, 34, a veteran open-wheel and sports car racer, and Magnussen, 30, a champion in sports cars, touring cars and single-seaters, will join the team for the three long-distance events during 2004, including the 12 Hours of Sebring, 24 Hours of Le Mans and the 1,000-mile Petit Le Mans. The 2004 driver lineup is as follows:
#3 Corvette C5-R
Ron Fellows
Johnny O'Connell
Max Papis
#4 Corvette C5-R
Oliver Gavin
Olivier Beretta
Jan Magnussen
The team will begin the upcoming season with a new six-speed gearbox from supplier Xtrac, engine performance enhancements and further aerodynamic modifications.
Corvette Racing's sixth full year of racing will commence at the 12 Hours of Sebring in March.
General Motors Corp. (NYSE: GM), the world's largest vehicle manufacturer, employs 342,000 people globally in its core automotive business and subsidiaries. Founded in 1908, GM has been the global automotive sales leader since 1931. GM today has manufacturing operations in 32 countries and its vehicles are sold in more than 190 countries. In 2002, GM sold more than 8.6 million cars and trucks, nearly 15 percent of the global vehicle market. GM's global headquarters is at the GM Renaissance Center in Detroit. More information on GM and its products can be found on the company's consumer website at www.gm.com.
-gm racing-


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Tuesday 20th November, 2012
VWR offer a full range of liquid handling solutions from pipette fillers and controllers through digital burettes and fully autoclavable pipettors and electronic pipettors.
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The long-standing war between Coca-cola (KO) and Pepsico (PEP) has gotten dirty, with Pepsi developing campaigns directly attacking Coke's most popular mascots and Coke scooping up some of Pepsi's biggest clients. Last year, Starwood Hotels (HOT), the company that owns the world's Sheraton, Westin and Four Points by Sheraton hotels, switched to Coke from Pepsi. This year, Dunkin' Donuts (DNKN) decided to change sides, signing a multi-year agreement with Coke after having sold Pepsi products for years.
Coke is the more popular choice - it has 42% of the market, while Pepsi has just 31% - but, of course, Coke is a dedicated drinks company. Pepsi is the owner of several major brands, such as Lipton, Fritos, Quaker and Doritos, among others. In this arena, Pepsi is winning. It has almost two-thirds of the U.S. salty snack market. In fact, roughly 24% of Pepsi's revenue comes from its North American snack business.
Pepsi also has a strong eye on emerging markets. Right now it has 60% of the Brazilian snacks market and it is looking to increase its revenues from emerging markets even further. In 2011, over one-third of Pepsi's revenue came from developing economies, like Brazil - up from 22% in 2006. Pepsi has an eye on China. It currently has more than $1.6 billion invested in gaining a foothold there. It also recently came to a strategic venture with one of the largest processed foods companies in China - Tingyi. The agreement, which recently gained shareholder and regulatory approval, will save Pepsi hundreds of millions in operating losses.
While these efforts are a good bit smaller than Coke's - the market leader plans to spend over $3 billion in China over the next three years and it has already spent $2 billion in India, with plans to spend another $2 billion - Pepsi may be in a better position.
Comparing Pepsi to Coke, there are a lot of "battles" that fall to Pepsi's favor.
Pepsi is priced lower - it is trading around $66 per share, while Coke is priced at $74 per share. Pepsi also pays a higher dividend at $2.06 (3.10% yield) versus Coke's $2.04 (2.80% yield). Pepsi has higher earnings growth expectations as well. Analysts say its earnings will increase by almost 8% a year on average over the next five years. In comparison, analysts estimate Coke's earnings will increase by just over 6% per annum on average over the next five years. At these rates, Pepsi is priced lower relative its future earnings. The company has a forward price to earnings ratio of roughly 15, versus Coke's 16.5. Both are lower than their industry's average of 19.4, but lower is certainly a good thing.
Pepsi beats Coke on a number of other metrics as well. For one, it enjoys stronger revenue growth. It was able to increase its quarter over quarter revenues by 11%, more than double Coke's 5.2% revenue growth and close to three times its industry average of 4.4%. Pepsi had a stronger increase in net operating cash flow as well (17% to Cokes 16%). In fact, the only metric that Coke really beats Pepsi in right now is the quick ratio, which is low in both companies. Coke's ratio is 0.78 while Pepsi's is just 0.62.
Of course, there are also competitors outside the Coke and Pepsi rivalry, like Dr. Pepper Snapple Group (DPS).
Dr. Pepper Snapple was spun off of Cadbury Schweppes in 2008. It recently traded at $40 a share with a $1.36 dividend (3.40% yield). Analysts estimate its earnings will grow at an average rate of 6.43% a year over the next five years. The company is priced low at 12.68 times its future earnings and has enjoyed strong earnings per share increases. While its revenue growth fell short of its peers at 3.5%, Dr. Pepper Snapple's quick ratio was right on par at 0.70.
In 2010, Dr. Pepper Snapple entered into priority brand agreements with Pepsi and Coke, ensuring that its popular Dr. Pepper brands would appear in all the various merchandising events and displays that both Coke and Pepsi participate in. This was a solid strategic move but its sales volume did not reflect that. That said, in 2011, Dr. Pepper Snapple had 40% of the market share in the U.S. when it comes to flavored carbonated soft drinks. Also in 2010, Dr. Pepper Snapple launched a Rapid Continuous Improvement program with the goal of freeing up resources (i.e. time and money) to build brand value. So far, the company has been successful, significantly reducing its inventory costs and increasing its dividends from 15 cents a quarter in March 2010 to 34 cents a quarter in March 2012.
I like both Coke and Pepsi. While Coke's aggressive investment strategy is attractive, so is Pepsi's comparatively strong metrics. I prefer Coke in this battle, but I wouldn't count Pepsi out. As far as Dr. Pepper Snapple goes, I like the dividend and the company in general. Its low revenue growth is a bit worrying though. I recommend this company as a hold, but one to keep a close eye on. One good sales report and I imagine Dr. Pepper's numbers could jump.
Disclosure: I have no positions in any stocks mentioned, and no plans to initiate any positions within the next 72 hours.


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Hoboken Photo Leftovers
Hoboken photo remains of the week: 12.3.2016
In the Hoboken Photo Leftovers gallery below:
- Photo 1: One stage of the 11th St. Poop Pump done. Road reopened.
- Photo 2: Cracking down on the illegal parking on 14th St.
- Photo 3: The building that formerly held the Five Guys Burgers and Fries was leveled.
- Photo 4: "Welcome to Peeling Hoboken" still peeling.
Just a few weeks left in 2016. Make it count!
About Hoboken Photo Leftovers
Hoboken Photo Leftovers is part of the Hoboken411 Photo of the Day series.
These are photos that didn't necessarily warrant an individual posting on Hoboken411.
They may have been related to other stories – or completely independent. These photographs are remnants of our travels in the past week. But equally important in maintaining an historical record of "life as we know it" in the Mile Square City.
At the same time, these photographs may also mirror the unique personal opinion of the publisher of Hoboken411.com.
Regardless, the pictures add to the "virtual encyclopedia" that this site now represents. Thank you for your readership!


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A Chat with Countywide Cooling & Heating
What services does your business offer and what makes your business stand out from the competition?
Countywide offers residential and light commercial HVAC service, install, and indoor air quality specialist. We provide prompt, professional service at a fair price.
What was the inspiration to start or run this business?
Countywide heating & cooling believes in giving the customer the best possible service. We want to be their preferred HVAC contractor.
What do you love most about your job?
Being able to take an unexpected mechanical emergency and find a solution for the customer's comfort and safety.
What is the best reaction you've ever gotten from a customer?
"For prompt, professional service, I trust the pros at Countywide Heating & Cooling" - David Backes


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Masterplan for Delta Properties. Consist of a regional shopping complex, offices, theme park, hotel, and a golf course. This is an Eco-green development with the preservation of existing indigenous trees, eco-system, and vegetation. A natural water stream forms the main spine of the development by connecting and linking all activities.
Project Category: Commercial
Project Status: Preliminary Design
Project Date: 2015
© 2014 · IDC Architects · All Rights Reserved


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LG LGIP-590F Battery for Optimus 7 E900 / Optimus 7Q / LGIP590 / Original
Original LG LGIP-590F Battery for LG Optimus 7 E900 & Optimus 7Q.
This is brand new rechargeable original LG LGIP-590F battery contain 1350mAh capacity, using 3.7v Lithium-ion cell made and developed by LG. Exact same battery that come with your phone.
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Time in Norway: 12:03 PM
Make a search for products & suppliers, articles & news.
Carbon capture and storage (CCS) is a central part of the Norwegian policy on energy and climate change.
Read the press release: Change in direction of commitment to Carbon Capture and Storage
The governments work on carbon capture and storage on Mongstad
In October 2006, the Norwegian government granted Statoil permission for the building of a combined heat and power plant (CHP) at Mongstad. At the same time, the Norwegian State and Statoil agreed on developing CCS technology at Mongstad in two stages: First, a CO2 Capture Technology Centre (TCM), followed by the construction of a large scale plant at a later stage. The large scale CCS project at Mongstad included CO2 capture, transport and storage from the CHP plant at Mongstad. Captured CO2 would be transported by pipeline for storage under the seabed in the North Sea.
The construction of the Technology Centre progressed according to plan and was opened in may 2011. TCM is the largest center of its kind, with an annual capacity for handling up to 100,000 tons of CO2. The Centre will test CO2 capture on two types of flue gases using two capture technologies, hence; the testing is also relevant to CCS on coal-fired power plants.
Since 2006, the Government and Statoil have worked together with the aim of establishing a large scale capture plant at Mongstad. The source of CO2 for the planned capture plant is the exhaust gas from the CHP plant. At full capacity, the CO2 emissions from the CHP plant may be up to 1.3 million tons of CO2 annually. CO2 was to be captured from a plant already in operation; hence only post-combustion capture was considered relevant for the CHP plant. CO2 capture from power generation has not been accomplished at this scale previously. The capture plant at Mongstad was to be established at a complex industrial area containing several sub-plants, all of which would be in normal operation during construction and operation of the capture plant. An important premise in the work was therefore to be attentive to the challenges such a project is facing. The project planning must carefully balance project progress, risk management, costs and technology development.
The inclusion of alternative capture technologies in the technology qualification process implied that qualification of capture technologies would be carried out prior to the engineering phase of the full scale project. Statoil, which was responsible for carrying out the project, estimates that the technology qualification would be in progress up to 3 years. The following engineering phase will last approximately two years, leading up to a basis for an investment decision presented for the Parliament no later than 2016. If qualification of at least one capture technology was completed before the three year period, the issue of technology selection would be addressed immediately.
Aqua Nor 2017 closed its doors after four fantastic days. The final count showed that no less than 27 110 visitors had found their way to the exhibition. This represents an increase of over 30% compared to Aqua Nor 2015.
In partnership with key customers,
Along with eight other graduates, he has developed SEAtrue,
"We've seen similar results in several other digitalization initiatives we've had lately.
In collaboration with Siemens,
Eimskip has strengthened its position in worldwide logistics services by acquiring 75% of the freight forwarding company SHIP-LOG.
For Sale Assets from the former BMV LAKSEVÄG YARD in Bergen, Norway! The entire shipbuilding and fabricating facility is closing and more than 500 lots is on sale.
We are proud to announce that Servogear has been chosen for the delivery of Servogear...
The associated activities will be managed by TechnipFMC Process Technology's center in Houston,
General enquiries:
Tel: +47 21 62 78 00Email: firstname.lastname@example.com
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Co-Published on SoccerWire.com
The Jefferson Open 3v3 was played over the weekend at West Creek Complex, one of the home venues of the Richmond Strikers. More than 100 teams from as young as the U-8/9 age group up to adult divisions competed in the tournament, a qualifying event for the Disney 3v3 World Championships.
Strikers teams represented the host club well claiming 13 division championships, as the local players prepare for the upcoming fall season. Two teams from Fredericksburg-based CFC Milan won division titles at the Jefferson Open, while sides representing other Virginia clubs such as Braddock Road Youth Club (BRYC) and the Richmond Kickers also took home championships. Another team composed of both Strikers and Kickers players took the Girls U-14/15/16 Orange Division.
Some independent squads went with satirical team names like 'Zlatans Nose Bighimovic Bois', the eventual champions of the U-15/16 Boys Recreational Division. Regardless of club affiliation or lack thereof, the top four teams in each division have advanced directly to the Disney 3v3 World Championships in Florida, with no need to go to a regional event in order to qualify.
Held in January 2016 at the ESPN Wide World of Sports Complex in Orlando, Florida following the conclusion of the Disney Soccer Showcase, the 3v3 World Championships play host to more than 800 teams annually from all over throughout the continental United States, Puerto Rico, and other nations such as Brazil, Canada and China.
The 2015 event featured teams from 27 U.S. states, including: Alabama, Arkansas, California, Colorado, Connecticut, Florida, Georgia, Illinois, Indiana, Iowa, Kansas, Maryland, Massachusetts, Michigan, Mississippi, Missouri, New Jersey, New York, North Carolina, Ohio, Oklahoma, Pennsylvania, South Carolina, Tennessee, Texas, Virginia and Wisconsin.
than 30 Virginia teams attended the 2015 World Championships, several of which qualified by way of the Jefferson Open. Among those teams were the Strikers Soccer IQ U-9 Boys, who went on to place second in Bracket A of the Invitational Division.
See below for a full list of champions from the Jefferson Open 3v3.
+Full Results
U-8/9 Recreational: Halifax Bertrum's Bandits
U-11/12 Recreational: Strikers Jaguars
U-15/16 Recreational: Zlatans Nose Bighimovic Bois
U-9: Strikers Barcelona
U-10/11: CFC Milan Soccer Nutz
U-11/12 Orange I: Strikers All Star Ballerz
U-11/12 Orange II: Strikers Soccer IQ
U-12 Black: CFC Milan Soccer Nutz
U-13/14: Strikers Arselona
U-14: Glen Allen Gunners
U-15/16: Strikers Orange
U-15 Black: Strikers Genetworx
U-16/17: Strikers Animaals
Men's Open: Kickers East Side Foreigners
U-10: Strikers Fire
U-11/12: BRYC Virginia's Diva-All Stars
U-12: Strikers Thunder
U-13/14: Strikers Redbacks
U-14/15/16 Orange: Kickers/Strikers Cleans on Fleek
U-14/15/16 Black: Strikers Destiny
Women's Open-HS: Strikers White


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Mahesh Kale
Founder of ICMA Foundation
ICMA Foundation was founded by Mahesh Kale, a young and talented artist living in the San Francisco Silicon Valley in California, USA. Mahesh has had the honor of having Pandit Shri Jitendra Abhisheki as his guru from 1991 for 8 years and has performed under his guidance with him all over India. Mahesh did his Bachelors in Electronics Engineering from University of Pune in India and got his Masters in Engineering Management from Santa Clara University in California. Apart from recently having mesmerized the audience at Sawai Gandharva Sangeet Mahotsav in Pune, India, Mahesh continues to inspire a motivated student body of about 150 students in San Francisco Bay Area.
Mahesh is ably guided in this pursuit by a few established and serial entrepreneurs and other successful individuals that have a wide range of expertise, from business acumen to creative arts and management skills, on his advisory and volunteer teams.
Our Team
Purva Gujar (Co-founder)
Abhijit Pandit
Ashwin Kapse
Asmita Bedekar
Avinash Parab
Bhaskar Ranade
Chaitali Phadnis
Deepti Joshi
Doyel Mukherjee
Indira Emmadi
Jayashree Jagannath
Konark Sarangi
Mahesh Kale
Milind Dharkar
Nitin Joshi
Padmaja Iyer
Priya Karkar
Rucha Heda
Santosh Mahabaleshwar
Satyan Vaidyanathan
Shekhar Hemnani
Shrivardhan Joshi
Sumit Ambokar
Varsha Prakash
Vidya Joshi
Vimal Singh
Yogesh Ayachit


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Vero Beach, Florida photographer and doTERRA essential oils wellness educator: Children, Seniors, Families, Engagement, Birth
I have been professionally photographing high school seniors, families, children, couples and pets for the last 6 years. My style is colorful, fun and clean. I gravitate more toward capturing the fleeting smiles of a real moment than forced smiles under pressure. Schedule a session with me and you will laugh, have fun and most importantly...immortalize this special season of you life.
I look forward to sharing your story.
…finished with this gallery. However, I know one extra sweet Mommy who has been extra patient, so I wanted to giveView full post »
… love like you've never been hurt. Sing like nobody's listening; live like it's heaven on earthView full post »
Last year at this time Jami entered my Mother's Day giveaway for a free photo session…and won. I like toView full post »
I couldn't go to bed without posting a few pics for her sleep deprived Mommy. This gorgeous newborn's MomView full post »
When we first discussed their photo shoot they mentioned they had a unique backyard. They weren't kidding! LittleView full post »
I love on-location photo shoots for moments like these. Moments when you forget (or just don't care) that I'View full post »
I once wondered why I was brought to Clovis, NM of all places. Then…I met the Hinkle Family and everythingView full post »
to not smile while looking at this picture. Show this family your support – leave a comment! 15 comments scores them aView full post »
I could tell this adorable little girl was no stranger to the paparazzi. She was alert and ready for her close-up fromView full post »
Maternity/newborn combo shoots. These are my favorites! They allow me to capture the family dynamic before and after theView full post »
I've been looking forward to this photo shoot for almost… a year?! Every time we tried to get together, lifeView full post »
I've been photographing this cute little lady since she was a month old. You can check out how much she'sView full post »
Love. Laughs. Beauty. Hope…and lots of books. That's what surrounded me as I walked into this amazing familyView full post »
© 2017 Kasey Mikelle Photography|ProPhoto Website by NetRivet Sites


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The Feed
The Feed
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How Massage Can Save Your Sex Life
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So you think you can spin on your dick
Recap of Serious News Stories and Butts You Can Look at Instead of Thinking About Them


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Summary of The Day: We'll drive through scenic Upstate New York and the Delaware Gap to Watkins Glen State Park.
You'll have free time to walk through the park before we continue on to Niagara Falls. There will be a tour of the American Side of the falls, including American Falls, Goat Island and Sister Island.
And we'll see the falls illuminated in a rainbow of colors at night.
Summary of The Day: See Niagara Falls like never before by taking a ride on the legendary Maid of the Mist boat ride.
During the winter months (November - March) we'll tour the Scenic Tunnels instead.
In the early afternoon we'll drive to Tannersville, PA, for some shopping at the Premium Outlets.
Summary of The Day: Depart from New Jersey to Pennsylvania and to the city of brotherly love Philadelphia.
Arriving in the historic area of Philadelphia we visit the famous Liberty Bell, one of the symbols of freedom in America, Constitution square and Congress Hall. Stroll Elfreth's alley the oldest continuously inhabited street in America. Continue on a panoramic tour of Philadelphia that includes the financial district, Benjamin Franklin Parkway, Historic Philadelphia and more.
Departing Philadelphia we see the famous "Rocky Steps", then continue north to Lancaster county home of the Amish people.
Ride on an authentic Amish Buggy through the Amish farm country and learn how they live without the benefit of modern technology, no electricity, running water, telephone service, or appliances. After the ride we visit the Amish marketplace where we can shop for handmade arts crafts and products.
We depart then for DC.
Summary of The Day: Start the day with a visit to the Lincoln, Washington, Korean and Vietnam Memorials.
We continue to the Arlington National Cemetery to see the changing of the guards and the Kennedy family gravesite. Next, visit the Mint and learn how the US tries to keep the US Dollar safe from counterfeiters. Continue to the Air and Space Museum before visiting the Capitol, Senate and White House (visit outside)to understand the core of the US government.
In the late afternoon we depart north for an evening arrival in New York.
*Single Occupancy Price applies when one person stays in one standard hotel room.
*Double, Triple, and Quadruple Price applies when two, three, and four people stay in one standard hotel room.
*Triple and Quadruple price does not guarantee a third or fourth bed in the room, as each room is equipped with two (2) beds only. Please check availability at check-in.
*Price for child applies when a 2-14 year-old child stays in one standard room as a third or fourth person.
*Maximum room capacity: 4 people including adults and child/infant.
*Infants under 2 years of age are free of charge.
Write a Review and earn 200 points. Attach photos to your review and earn 25 points per photo.
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Questions previously answered may have different answers due to many reasons: season (date and year of travel), rates, availability, etc.Please check the Rewards4Fun Program FAQ for more information.Ask Us
Dear Eric,
This 4-day tour package offers multilingual tour guide service. The tour price includes some attraction admissions already.
Please double check if the similar option from TakeTours offers the same.
Thank you very much for your inquiry.
Best Regards,
Customer Service Rep
Dear Thomas,
Thanks for your inquiry.
There are three major airports in New York: JFK, LGA and EWR. JFK and LGA airport are relatively closer to the pickup location.
You can consider the Park Central New York hotel in Manhattan area which is less than 1 mile from the meeting point. You can book via blow link.
Best Regards,
Customer Service Rep
Dear Thomas,
Thanks for your inquiry.
This four day tour includes 3-night hotel accommodations and the group will return New York for an early evening arrival around 8:00 pm.
If you need hotel extension in New York, please have a look in the link below for options,
Best Regards,
Customer Service Rep
Dear Customer,
Because the hotels are subject to confirmation based on availability for your travel dates at the time we receive your booking, we are unable to confirm if the hotels will include breakfast.
Therefore we recommend you to prepare all meal expenses for breakfast, lunch and dinner.
Your tour guide will arrange meal stops during the tour travel dates at fast food restaurants, buffet restaurants, and/or food courts etc. You choose your own meals from the available options and pay at your own cost.
Best Regards,
Customer Service Rep
Dear A S Lim,
They are of same tour operator.
Tour 29-600 is US side only: A Canadian visa is NOT required to join this tour.
Tour 29-597, Guests who have a valid U.S. passport/a valid Canadian Visa may partake in a night tour on the Canadian side of Niagara Falls and see the falls illuminated with a rainbow of colors. Guests who cannot visit the Canadian side can stay overnight on the U.S side. Please note that the night tour is only conducted on the Canadian side. Please make a note if you wish to only visit the U.S side by leaving a comment on the check-out page when you book the tour online. So this is not a must for the tour, you can prepare visa if you want.
Best Regards,
Customer Service Rep
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- Svengali syzygy hegemon repugnant white nationalist, white supremacist
Definition of dispensator
1 obsolete : dispenser
2 obsolete : one that manages or administers
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Origin and Etymology of dispensator
Middle English dispensatour, from Medieval Latin dispensator, from Latin, household manager, treasurer, from dispensatus + -or
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Warren Dermatology & Allergy
- Dermatology |
- Allergy and Immunology
- 735 Niles Cortland Rd SE Warren, OH 330-856-6365
Doctors in Warren Dermatology & Allergy
Patient Reviews3.9
The Overall Average Patient Rating of Warren Dermatology & Allergy when asked is excellent. Warren Dermatology & Allergy has been reviewed by 16 patients. The rating is 3.9 out of 5 stars.
The average wait time to see a doctor at Warren Dermatology & Allergy as provided by patient reviews is 10 minutes. By comparison, the national average for a pre-vist wait time is 21 minutes.
A dermatologist is a doctor who has extensive training and knowledge of the skin, scalp, hair and nails and treats conditions that affect those areas. These doctors will evaluate any abnormality, blemish or lesion on the skin in order to determine the cause and will determine a course of treatment.
Dermatologists provide patients with full body scans in order to identify any signs that are indicative of an illness that requires treatment, such as skin cancer. These specialists may also provide cosmetic services, such as mole removal, scar diminishing treatments and even botox and face lifts.
An allergy & immunology specialist is a physician who is specially trained in matters pertaining to chronic and acute allergies, as well as deficiencies of the immune system. The doctor will determine whether an allergy, which attacks our immune system, is present. They'll also determine the cause, whether it be environmental triggers like trees and pollen, food-borne like peanuts and dairy, the venom of insects like bees, or a medication like penicillin.
In addition to determining the allergen causing an immunological response in a patient, the specialist will treat the symptoms caused by the reaction.
- Dermatology
- Allergy and Immunology
- Topiwala National Medical College
- Ohio State University College Of Medicine
- English
Health Insurance Accepted
- First Health
- United Healthcare
- Multiplan
- BCBS Blue Card
- Cigna
- Data not available
Hospital Affiliations
- West Palm Beach VA Medical Center Palm Beach Gardens, FL
Information about group practices
What is a Group Practice?
According to The Medical Group Management Association, a group practice is any relationship between three or more physicians who share facilities, expenses, profits and other resources like support staff and equipment.
Group practices tend to fall into two categories: those that organize around a particular medical specialty and those that encompass several specialties like East Boston Neighborhood Health that specializes in internal medicine.
Why Group Practice?
As medicine became more complex in the twentieth century, the need for group practices made more sense. Physicians found it impossible to know everything about the emerging drugs and technologies on the medical landscape. In addition, the cost of providing a full range of diagnostic services, such as tests and X-rays, in one location became prohibitive to the individual practitioner. Hence, doctors from various disciplines began to team together in order to provide more comprehensive care to their community of patients.
Benefits of Group Practice
- Access to doctors from various disciplines for referrals and advice
- Better coverage on weekends and off-hours
- One-stop clinics for comprehensive care and testing


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Enter a valid city, state or zip code
Valid at the 2650 E. Grand River Ave location in East Lansing only. Coupon valid with dine in, carry out or delivery. Delivery charges may apply. Limit one per order. Not valid with any other coupon. With Valpak® coupon only. Coupon void if altered. Expires Mon Sep 04 23:59:59 EDT 2017.
The Pepperoni Feast is an every day, all day menu item - not a promotion. Dine in, carry out, delivery. Delivery charges apply. Coupon void if altered.
Featured in this month's Blue Envelope
2650 E Grand River Ave
East Lansing, MI 48823-5608
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Scene Info Released Jun 17, 2008
DVD: Face Invaders 3
Pornstars: Tristan Kingsley, Trent Soluri
Niches: Gonzo, Facial Cumshot, POV, Blowjob Only
9,003 views
Tristan Kingsley doesn't fool around. She knows what kind of outfit will get a man hard. After kneeling submissively in front, she sucks Tristan off until he cums all over her pretty face.
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text: I've only got these images to go by in identifying the little model: in one she's called "Viktoria" by the photographer, Deek – and I'm assuming there's just one little blonde to start with. I don't even know if "Deek" is male or female: I added "Golovach" since some of the images in the photostream have that as the watermark. "Fashionista" is my improvement on Google Translate's rather clumsy "Fashion-monger" for the title of the first shot: you can see she has her cool shades and lots of colourful beauty products. The framing on a couple show how far back these go – nine years in some cases. (Nick 11 as ever contributes encouraging comments – the rather banal "Beautiful!" and "Cute!"…..)


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Mixed Tax Manager
- Recruiter
- Clark Wood
- Location
- Kirton End
- Posted
- 09 Aug 2017
- Closes
- 21 Sep 2017
- Sector
- Finance
Mixed Tax Manager
£35,000 - £40,000
Tax Specialists Clark Wood are working with a leading independent firm in Boston who are currently seeking a Mixed Tax Manager to join their team.
The role consists of a mixture of compliance and advisory work and would involve managing your own portfolio of a diverse range of clients including OMBs, entrepreneurs, high net worth individuals and non-domiciled individuals.
The ideal candidate will be CTA or ACA qualified and our client is offering a very competitive salary, excellent benefits & holiday package for the right individual.
This is a fantastic opportunity to move up the ranks within a highly reputable firm.
Duties & Responsibilities:
Manage a portfolio of clients, being their first point of contact
Provision of tax consultancy, compliance, planning and advice
Providing support to partners on more complex projects
Reviewing work done by junior staff
Provide intelligent and creative solutions to client tax issues both reactively and proactively
Dealing with HMRC correspondence and client queries including obtaining relevant or requested information
Working closely with Partners
Train and mentor junior staff members
Build and maintain strong client relationships
ACA/CTA Qualified (ideally)
(Finalist/ Part Qualified also considered)
ATT Qualified/ QBE also considered
For further information on this role please contact Jack Wyatt at Clark Wood
If this specific vacancy is not quite what you are looking for please contact us to investigate alternatives; you can send your CV to this job or contact us directly. Refer a friend or colleague to us and receive a minimum of £200 in vouchers if we assist them in securing a permanent role


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1300 36 33 32
Sunday 3 September is Father's Day! Buy Dad a book from our Fantastic Father's Day Book Catalogue...
Buy Mary Tudor by Judith M. Richards from Australia's Online Independent Bookstore, Boomerang Books.
Book Details
(June 2008)
» Have you read this book? We'd like to know what you think about it - write a review about Mary Tudor book by Judith M. Richards and you'll earn 50c in Boomerang Bucks loyalty dollars (you must be a Boomerang Books Account Holder - it's free to sign up and there are great benefits!)
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Judith M. Richards was previously senior lecturer in History at La Trobe University, and is now a research associate. She has published a number of studies of topics in early modern history, and has more recently focussed on English and British monarchy from 1553- 1642.
Phone: 1300 36 33 32
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text:
Induce Labor Naturally in a Safe Way... "How to Induce Labor Naturally" "Imagine Having Your Little Baby On Your Arms Within 48 Hours From Now!" Maternity Acupressure Helps You To Induce Labor Naturally Without Risking Your Baby's Health Maternity Acupressure is safe for mother and baby.
Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.
Here's just a fraction of what you will discover inside the book:
So, if you are looking for a safe and effective way to induce labor naturally at home, then don't waste your time trying to find something else.


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- Flashback -
"Get something other than orange and black for once," Sasuke growled to him from the other side of the clothes rack in Dills at the mall. "I get stuff in blue too," Naruto answered quietly, his baby blue eyes downcast, pretending to look at the price tag of a shirt. Sasuke snorted and said, "Whatever, hurry up."
Naruto grabbed another sleeveless orange shirt and followed Sasuke to the check out. Sasuke paid for their things and Naruto got the bags, following Sasuke to his corvette. Naruto put the bags in the trunk then climbed into the car.
Sasuke drove them back to campus wordlessly. Naruto carried the bags to Sasuke's room. He placed Sasuke's bags on his bed and turned to leave, walking into the other boy. Sasuke smirked at him, and gently tilted Naruto's chin upward. Gently, Sasuke kissed the blond, something he so rarely did. After getting over his initial shock at Sasuke's kindness, Naruto closed his eyes and kissed back eagerly. Sasuke slid his hand from Naruto's chin to his throat, not squeezing, yet. Sasuke bit Naruto's lip, drawing blood, making Naruto whimper softly. Sasuke kissed him more forcefully, backing Naruto into the wall. Naruto returned the kiss, hoping Sasuke wouldn't choke him. The kiss lasted a moment longer. Sasuke pulled away, smirking, his hand still around Naruto's throat. He smirked, staring into the blond's eyes, which held fear and a mix of love. Sasuke released him, and Naruto exited the room, feeling Sasuke's eyes on his back.
Naruto returned to his room, closing the door with a soft sigh.
"Why are you with him?" Kiba, his roommate, asked. "Because...," Naruto replied, trailing off, then shaking his head as he walked to his bed and flopped down on it. Kiba flipped the page in the magazine he was reading. "You shouldn't stay with him if he treats you this badly," his roommate advised. "But...," Naruto tried to protest. "You know I'm right Naru," Kiba said, looking over at him, his chocolate brown eyes full of concern.
Naruto didn't bother with a reply and Kiba got up a few moments later, leaving the room. Naruto laid there, thinking of Sasuke.
- End flashback-
Naruto stared at his reflection in the lake. His blond hair seemed somehow paler, his skin too. His eyes were full of sadness, but he had done as he had to. He sighed, knowing that didn't make it hurt any less though.
- Flashback-
"We need to talk," Naruto said, standing just inside the doorway to Sasuke's room. "What about?" Sasuke asked, his eyes cold, but his interest sparked. "Do you care for me? Even the tiniest bit?" he asked, trying not to cringe away from the ice cold stare. "Of course I care," Sasuke answered. "Then you have to take me as I am, not as who you want me to be, because if you really did care, you wouldn't be trying to change me," Naruto said, looking his boyfriend in his onyx gray eyes.
Sasuke's eyes hardened, Naruto barely had time to react before Sasuke's fist connected with his jaw. The blond reeled sideways, his shoulder hitting the wall. Sasuke smirked at him, cold and cruelly. Naruto stood straight, his hands clenched into fists, tears welling in his baby blue eyes. Naruto stared at Sasuke a moment longer before turning around and slamming the door behind him.
- End flashback-
Naruto had loved Sasuke, he thought despite his coldness, the other boy had loved him too. Obviously, that hadn't been so. Naruto ran his hand through his hair, deciding to get up and go back to his room. See if Kiba was interested in doing something. He slouched slightly as he walked, staring at his dark blue converse, his slightly lighter jeans covering them mostly.
When he opened the door to his room, he heard Kiba in the bathroom, brushing his teeth.
"Hey Kiba, got any plans?" Naruto asked, laying on his bed. "Nope," he answered, walking out of the bathroom. "How about some video games down at the lounge?" Naruto asked. "Sure," Kiba nodded.
Naruto stood and followed Kiba out of the room. They walked side by side in silence to the lounge. Kiba took a seat on the couch while Naruto crouched in front of the game rack.
"Whacha wanna play?" he asked. "Dunno," Kiba replied. Naruto rolled his eyes and grabbed Soul Caliber III, putting it in the PS2. He tossed Kiba a controller and grabbed his, sitting beside the brunette.


text: Contents Edit Speedy and solid workmanship! Furnishings in the Novigrad style, dining tables, canopy beds, alcove accessories and larder ware. All for prices that can't be beat. Our customers hail from Oxenfurt itself! Want to dine like a duchess? Go see the Brothers Gomes! Retrieved from "http://witcher.wikia.com/wiki/Gomes_%26_Bros._Carpentry_Services?oldid=257078" Categories: Hearts of Stone notice board postings Add category Cancel Save


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Sci-Fi Month continues! Today I'm going to be talking about my personal Top 5 Science Fiction Heroines. I love me some female protagonists, in fact if I pick up a book while I'm out shopping and I don't find the slightest sniff of a female character in the blurb I will not buy that book. I've got nothing against male protagonists, but I'm 23 and I'm tired of sausage fests.
Cosima Niehaus from Orphan Black: Another story with a heroine for everyone. I started watching Orphan Black earlier this year and I love it! Tatiana Maslany is the most amazing actress and I love all of the clones, but there's just something about Cosima which always makes her the first clone I think of when I think about the show. She's adorable; I love her passion for science and I really wish my hair looked like hers.
Georgia Mason from the Newsflesh trilogy by Mira Grant: For those of you who have been following my blog for a while this should come as no surprise. I adore the Newsflesh trilogy, and after reading Feed earlier this year Georgia quickly became one of my favourite heroines of all time. Who knew anyone could love a journalist so much!
Sarah Connor from the Terminator series: I grew up watching the Terminator films with my Dad, and no matter how many times I watch it I never get tired of Terminator 2. What I love about Sarah is that she's actually incredibly flawed, and yet she's still an incredibly competent, resilient, tough lady. For an action heroine of the early 90s she's awesome; she isn't put into a box as a hardcore, emotionless bitch, but she's also far from typically feminine. I have a lot of time for Sarah Connor, and I was very disappointed when she didn't make an appearance in Terminator 3!
Are there any heroines of sci-fi that you love?


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02:27AM, Wednesday 29 May 2013
Young people in the Royal Borough have been warned about the potentially lethal danger of 'laughing gas'.
The Borough's Drug and Alcohol Action Team (DAAT) has issued the warning after a number of young people were found in possession of nitrous oxide cartridges.
The cartridges can be bought for as little as 30p over the internet and inhaling the gas can kill in extreme cases.
Thames Valley Police has discovered increasing numbers of empty cartridges and there have been reports by residents of seeing young people with canisters inhaling the gas from balloons.
Chief Inspector Lee Townsend, deputy local police area commander, said: "It is often used at festivals and raves and is usually inhaled from a balloon.
"It can play havoc on the respiratory system and people can die from it as the larynx can close down and cause choking."
Cllr David Coppinger, cabinet member with responsibility for the DAAT, said: "It is very worrying that this legal substance is being misused by some of our more vulnerable young people. Used in this way it can have terrible long- term consequences.
"I am glad that the DAAT is working in partnership with Thames Valley Police to educate young people of the potential dangers of nitrous oxide."
Most Shared
Most Commented
Top Ten Articles
Two people died following a three-car crash near the Legoland roundabout in Windsor last night.
Two Slough men who launched an 'unprovoked attack' on a man and a woman in Maidenhead town centre have been sentenced to four and a half years in prison.


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Many UN resolutions establish standing UN committees or Agencies. Most of these committees and Agencies are staffed and operated by the UN Secretariat; some have national branches in all member nations or all interested ones. The day-to-day operations of these committees are transparent to voting members of the UN.
There are a few exceptions, where UN Committees are overseen by UN member states. Each of these committees has established its own set of rules governing the responsibilities of committee members. These committees still make use of UN Secretariat for their day-to-day operations.
- The official forum is here.


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Daisy May Retro Print 7/8 Length Slim Fit Trousers, Turquoise

Irish designer Daisy May presents these vibrant trousers which would be a bright update for your separates collection. Wear with the matching top as an excellent alternative to a dress for a family occasion.

Made from lightly woven fabric with a retro print throughout. Styled with a slim leg and ankle grazing 7/8 length. Finishing touches include side pockets and a concealed hook and eye and zip fastening.

Brand: Daisy May

Style Code: D50272

Colour: Turquoise

Leg Length: 27"/69cm approx.

Materials: 68% Polyester, 32% Polyacrylic

Wash Care: Hand wash only

P-D50272-TURDaisy May Retro Print 7/8 Length Slim Fit Trousers, Turquoise
€ 0.00 to 0.00


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(800) 403-8861
Pear Tree Greetings, Inc.
10 years in business1985 Lookout Dr
North Mankato, MN 56003-1720
Additional Email Addresses
- email@example.com
Find a Location
BBB File Opened: 09/19/2011
Business Started: 04/09/2007
Business Started Locally: 04/09/2007
Business Incorporated: 10/25/2011 in MN
Type of EntityCorporation
Business Management
- Stephanie Bottner, General Manager
- Customer Service, Owner/Manager
Business Category
- Greeting Cards - Wholesale & Manufacturers
- Gift Baskets & Parcels
- Greeting Cards - Retail
- Invitations & Announcements
- Labels - Paper
- Halloween Supplies
- Religious Goods
- Wedding Supplies & Services
- Baby Accessories & Services
- Bridal Supplies - Wholesale & Manufacturing
- Magnets & Magnetic Devices
Service AreaWe service the following area(s): South Central MN
Alternate Business Names
- Pear Tree Greetings
Licensing, Bonding or RegistrationThis business is in an industry that may require professional licensing, bonding or registration. BBB encourages you to check with the appropriate agency to be certain any requirements are currently being met.
Refund & Exchange Policy:We want you to be happy with your order, and so we stand behind the quality of all our products. If for some reason you are not completely satisfied, tell us. We'll make it right. Guaranteed.
Pear Tree Greetings celebrates life's sharable moments with our unique collection of personalized, high-quality invitations, photo cards and stationery. Shop birth announcements, Save the Dates, Christmas cards, graduation invites and more!
BBB Reason for Ratings
Business Profile
Licensing information is provided in the BBB Business Profiles to inform the public about industries that may require professional licensing, bonding, or registration. Better Business Bureau encourages you to check with the appropriate agency to be certain any requirements are currently being met.
Advertising Review
BBB promotes truth in advertising by contacting advertisers whose claims conflict with the BBB Code of Advertising. These claims come to our attention from our internal review of advertising, consumer complaints and competitor challenges. BBB asks advertisers to substantiate their claims, change ads to make offers more clear to consumers, and remove misleading or deceptive statements.
Government Actions
BBB reports on known significant government actions involving the business's marketplace conduct.
Out of Business
BBB reports on a company that is out of business for three years from the date the company closes its doors or ceases to do business.
Misuse of Better Business Bureau Name/Logo
BBB reports on unauthorized use of the Better Business Bureau's name and/or logo for as long as the business continues to use it in any advertising, or for one year after the business ceases any repeated unauthorized uses.
BBB reports on a business's bankruptcy as long as the business remains in bankruptcy.
Mail Returned
BBB reports when mail sent to the business was returned by the Postal Service.


text:
Why my skin is so itchy will be the basic question for some people who are doing the intensive skin treatment. Usually, they are using the product which contains of high dosage from some chemical substances which can create certain reactions on skin such as itchiness, redness, acne and also dryness.
Knowing Deeply about Why Is My Skin So Itchy
Source: lightskincure.org
There are many reasons for you to realize about why is my skin so itchy, when you feel itchy on skin face then it can be the skin reaction for the usage of skin treatment products. Those products might possibly contain the chemical substances which not only make your skin itchy but also dryness and redness on skin. That's why the usage of those types of products should be under control from skin dermatologist, to see how the product will be really working deep inside your skin.
The Causes of Why Is My Skin So Itchy
There are some causes for the question about why is my skin so itchy, it can be about the skin irritation which possibly happen when you pass the time for the skin treatment. Usually, some skin treatment products will give you the precaution before you use those products that there will be some skin reactions such as redness, itchiness, or dryness. But normally, it will only happen for about one week at the first treatment. When you always feel those skin problems, though you already use those products for more than 1 month it means that the product is not working properly for your skin and will only give bad impacts for your skin.
That's why the control from skin dermatologist is really important, so you will be avoided from some skin problems which can be very torturing, especially with the question of why is my skin so itchy. While you do the intensive treatment, you will possibly use the night cream. That's why people usually ask the question about why is my skin so itchy at night, and this can be the skin reaction because the usage of night cream. But always remember that the itchiness will only happen for short time at the beginning time when you use the night cream, but when it is always happen for long time then this is the sign that the cream is only give bad impact for your skin.
Why is my skin so itchy causes are some causes which you should need to understand about the itchiness on skin because the usage of some skin treatment products. For the best possible way, the consultation with skin dermatologist is really important, because they usually provide you with the skin treatment products which will be really working for your skin. You also don't need to worry because the usages of those products are under the control from the skin dermatologist, so the possibility for you to have the healthy skin is high. So you don't need to ask the question about why is my skin so itchy.
Always remember that you should be very selective when you are about to make a choice for the skin treatment products, because there are so many types of unreliable skin care products on the market nowadays. Be a smart buyer, and you will never need to answer the question about why is my skin so itchy.
Summary: Why is my skin so itchy is the common question which always appears on people's mind when they have a problem with the wrong skin care treatment.


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Hubei Provincial Key Laboratory of Developmentally Originated Disease
Hubei Provincial Key Laboratory of Developmentally Originated Disease
Wu S.-Z.,Wuhan University |
Peng F.-F.,Wuhan University |
Li J.-L.,Gannan Medical University |
Ye F.,Wuhan University |
And 3 more authors.
American Journal of Physiology - Renal Physiology | Year: 2014
Glomerular matrix accumulation is a hallmark of diabetic renal disease. Serine/threonine kinase PKC-β1 mediates glucose-induced Akt S473 phosphorylation, RhoA activation, and transforming growth factor (TGF)-β1 upregulation and finally leads to matrix upregulation in mesangial cells (MCs). It has been reported that glucose-induced PKC-β1 activation is dependent on caveolin-1 and the presence of intact caveolae in MCs; however, whether activated PKC-β1 regulates caveolin-1 expression and phosphorylation are unknown. Here, we showed that, although the caveolin-1 protein level had no significant change, the PKC-β-specific inhibitor LY-333531 blocked caveolin-1 Y14 phosphorylation in high glucose (HG)-treated MCs and in the renal cortex of diabetic rats. The Src-specific inhibitor SU-6656 prevented the HG-induced association between PKC-β1 and caveolin-1 and PKC-β1 membrane translocation, whereas PKC-β1 small interfering RNA failed to block Src activation, indicating that Src kinase is upstream of PKC-β1 activation. Although LY-333531 blocked PKC-β1 membrane translocation, it had no effect on the PKC-β1/caveolin-1 association, suggesting that PKC-β1 activation requires the interaction of caveolin-1 and PKC-β1. PKC-β1-mediated Akt S473 phosphorylation, RhoA activation, and fibronectin upregulation in response to HG were prevented by SU-6656 and nonphosphorylatable mutant caveolin-1 Y14A. In conclusion, Src activation by HG mediates the PKC-β1/caveolin-1 association and PKC-β1 activation, which assists in caveolin-1 Y14 phosphorylation by Src kinase. The downstream effects, including Akt S473 phosphorylation, RhoA activation, and fibronectin upregulation, require caveolin-1 Y14 phosphorylation. Caveolin-1 is thus an important mediator of the profibrogenic process in diabetic renal disease. © 2014 the American Physiological Society.
Jin J.,Wuhan University |
Peng C.,Wuhan University |
Wu S.-Z.,Wuhan University |
Chen H.-M.,Wuhan University |
And 2 more authors.
Acta Pharmacologica Sinica | Year: 2015
Aim: RhoA/ROCK signaling plays an important role in diabetic nephropathy, and ROCK inhibitor fasudil exerts nephroprotection in experimental diabetic nephropathy. In this study we investigated the molecular mechanisms underlying the protective actions of fasudil in a rat model of diabetic nephropathy. Methods: Streptozotocin (STZ)-induced diabetic rats, to which fasudil or a positive control drug enalapril were orally administered for 8 months. Metabolic parameters and blood pressure were assessed during the treatments. After the rats were euthanized, kidney samples were collected for histological and molecular biological studies. VEGF, VEGFR1, VEGFR2 and fibronectin expression, and Src and caveolin-1 phosphorylation in the kidneys were assessed using RT-PCR, Western blot and immunohistochemistry assays. The association between VEGFR2 and caveolin-1 was analyzed with immunoprecipitation. Results: Chronic administration of fasudil (30 and 100 mg·kg-1 ·d-1) or enalapril (10 mg/kg, bid) significantly attenuated the glomerular sclerosis and albuminuria in the diabetic rats. Furthermore, fasudil treatment prevented the upregulation of VEGF, VEGFR1, VEGFR2 and fibronectin, and the increased association between VEGFR2 and caveolin-1 in the renal cortices, and partially blocked Src activation and caveolin-1 phosphorylation on tyrosine 14 in the kidneys, whereas enalapril treatment had no effects on the VEGFR2/Src/caveolin-1 signaling pathway.Conclusion:Fasudil exerts protective actions in STZ-induced diabetic nephropathy by blocking the VEGFR2/Src/caveolin-1 signaling pathway and fibronectin upregulation. Thus, VEGFR2 may be a potential therapeutic target for the treatment of diabetic nephropathy.
Xu D.,Wuhan University |
Xu D.,Hubei Provincial Key Laboratory of Developmentally Originated Disease |
Bai J.,Wuhan University |
Zhang L.,Wuhan University |
And 6 more authors.
Toxicology Research | Year: 2015
Previous studies have indicated that the intrauterine growth retardation (IUGR) fetus is faced with a high susceptibility to adult metabolic syndrome (MS). Non-alcoholic simple fatty liver (NAFL) is considered to be the hepatic manifestation of MS. In the present study, we evaluated the susceptibility of high-fat diet-induced NAFL in female adult IUGR offspring rats, induced by prenatal nicotine exposure, and we further explored the underlying intrauterine programming mechanism for this phenomenon. The IUGR rat model was established by prenatal exposure to nicotine (2 mg kg-1 d-1), the liver tissues from female fetuses and female adult offspring fed with normal or high-fat diets were collected. The female adult offspring in the nicotine-exposed group showed low birth weights and postnatal catch-up growth, as well as severe NAFL under high-fat diets. Moreover, increased gene expression involved in the hepatic insulin-like growth factor 1 (IGF1) pathway, gluconeogenesis and lipid synthesis, and decreased gene expression of lipid output accompanied with elevated serum triglyceride levels, was observed. The female fetuses in the nicotine-exposed group showed down-regulated hepatic IGF1 pathways, and also exhibited similar patterns of increased gluconeogenesis, lipid synthesis and decreased lipid output to those in the adults. The present study demonstrates the intrauterine origin of increased susceptibility to high-fat diet-induced NAFL in female offspring rats by prenatal nicotine exposure, which is most likely mediated by "two intrauterine programming". That is, the first glucocorticoid-IGF1 axis programming induces postnatal catch-up growth, aggravates glucose and lipid metabolic disorders, and leads to an increased susceptibility to adult NAFL, while the second hepatic glucose and lipid metabolic programming enhances hepatic lipogenesis and reduces lipid oxidation and output, promoting NAFL. This journal is © The Royal Society of Chemistry 2015.
Wen Y.,Wuhan University |
Li J.,University of Lorraine |
Wang L.,Wuhan University |
Tie K.,Wuhan University |
And 5 more authors.
Arthritis Research and Therapy | Year: 2014
Introduction: The objective of this study was to investigate the possible role of UDP-glucose dehydrogenase (UGDH) in osteoarthritis (OA) and uncover whether, furthermore how interleukin-1beta (IL-1β) affects UGDH gene expression. Methods: UGDH specific siRNAs were applied to determine the role of UGDH in proteoglycan (PG) synthesis in human articular chondrocytes. Protein levels of UGDH and Sp1 in human and rat OA cartilage were detected. Then, human primary chondrocytes were treated with IL-1β to find out whether and how IL-1β could regulate the gene expression of UGDH and its trans-regulators, that is Sp1, Sp3 and c-Krox. Finally, p38 mitogen-activated protein kinase (MAPK) inhibitor SB203580 and stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) inhibitor SP600125 were used to pick out the pathway that mediated the IL-1β-modulated PGs synthesis and gene expression of UGDH, Sp1, Sp3 and c-Krox. Results: UGDH specific siRNAs markedly inhibited UGDH mRNA and protein expression, and thus led to an obvious suppression of PGs synthesis in human articular chondrocytes. UGDH protein level in human and rat OA cartilage were much lower than the corresponding controls and negatively correlated to the degree of OA. Decrease in Sp1 protein level was also observed in human and rat OA cartilage respectively. Meanwhile, IL-1β suppressed UGDH gene expression in human articular chondrocytes in the late phase, which also modulated gene expression of Sp1, Sp3 and c-Krox and increased both Sp3/Sp1 and c-Krox/Sp1 ratio. Moreover, the inhibition of SAP/JNK and p38 MAPK pathways both resulted in an obvious attenuation of the IL-1β-induced suppression on the UGDH gene expression. Conclusions: UGDH is essential in the PGs synthesis of articular chondrocytes, while the suppressed expression of UGDH might probably be involved in advanced OA, partly due to the modulation of p38 MAPK and SAP/JNK pathways and its trans-regulators by IL-1β. © 2014 Wen et al.
Zhang C.,Wuhan University |
Xu D.,Wuhan University |
Xu D.,Hubei Provincial Key Laboratory of Developmentally Originated Disease |
Luo H.,Wuhan University |
And 6 more authors.
Toxicology | Year: 2014
The hypothalamic-pituitary-adrenal (HPA) axis is one of the most important neuroendocrine axes and plays an important role in stress defense responses before and after birth. Prenatal exposure to xenobiotics, including environmental toxins (such as smoke, sulfur dioxide and carbon monoxide), drugs (such as synthetic glucocorticoids), and foods and beverage categories (such as ethanol and caffeine), affects fetal development indirectly by changing the maternal status or damaging the placenta. Certain xenobiotics (such as caffeine, ethanol and dexamethasone) may also affect the fetus directly by crossing the placenta into the fetus due to their lipophilic properties and lower molecular weights. All of these factors probably result in intrauterine programming alteration of the HPA axis, which showed a low basal activity but hypersensitivity to chronic stress. These alterations will, therefore, increase the susceptibility to adult neuropsychiatric (such as depression and schizophrenia) and metabolic diseases (such as hypertension, diabetes and non-alcoholic fatty liver disease). The "over-exposure of fetuses to maternal glucocorticoids" may be the main initiation factor by which the fetal HPA axis programming is altered. Meantime, xenobiotics can directly induce abnormal epigenetic modifications and expression on the important fetal genes (such as hippocampal glucocorticoid receptor, adrenal steroidogenic acute regulatory protein, et al) or damage by in situ oxidative metabolism of fetal adrenals, which may also be contributed to the programming alteration of fetal HPA axis. © 2014 Elsevier Ireland Ltd.
Wen Y.,Wuhan University |
Qin J.,Wuhan University |
Deng Y.,Wuhan University |
Wang H.,Wuhan University |
And 4 more authors.
Biochemical and Biophysical Research Communications | Year: 2014
UDP-galactose-4-epimerase (GALE) is a key enzyme catalyzing the interconversion of UDP-glucose and UDP-galactose, as well as UDP-N-acetylglucosamine and UDP-N-acetylgalactosamine, which are all precursors for the proteoglycans (PGs) synthesis. However, whether GALE is essential in cartilage homeostasis remains unknown. Therefore, we investigated the role of GALE in PGs synthesis of human articular chondrocytes, the GALE expression in OA, and the regulation of GALE expression by interleukin-1beta (IL-1β). Silencing GALE gene with specific siRNAs resulted in a markedly inhibition of PGs synthesis in human articular chondrocytes. GALE protein levels were also decreased in both human and rat OA cartilage, thus leading to losses of PGs contents. Moreover, GALE mRNA expression was stimulated by IL-1β in early phase, but suppressed in late phase, while the suppression of GALE expression induced by IL-1β was mainly mediated by stress-activated protein kinase/c-Jun N-terminal kinase pathway. These data indicated a critical role of GALE in maintaining cartilage homeostasis, and suggested that GALE inhibition might contribute to OA progress. © 2014 Elsevier Inc. All rights reserved.
Cheng Q.,Wuhan University |
Cheng Q.,Hubei Province Key Laboratory of Allergy and Immunology |
Dong L.,Wuhan University |
Dong L.,Hubei Province Key Laboratory of Allergy and Immunology |
And 11 more authors.
AIDS Research and Human Retroviruses | Year: 2015
RNA interference has shown great potential for the treatment of HIV-1. Vectors derived from prototype foamy viruses (PFVs) with a nonpathogenic nature are very promising gene transfer vehicles in anti-HIV gene therapy. In this article, three short hairpin RNAs (shRNAs) targeting the conserved regions of the HIV-1NL4-3 5′ long terminal repeat (LTR) were first designed. We then constructed novel recombinant PFV vector plasmids, pΦ-H1-shRNAs, expressing these shRNAs under the control of the H1 RNA promoter. To detect the efficacy of these ΔΦ-H1-shRNAs for the inhibition of HIV-1 replication, we performed a dual-luciferase reporter assay, RT-qPCR, ELISA, western blotting, and a lactate dehydrogenase (LDH) assay by transient transfection in 293T cells. The results suggest that these novel shRNAs driven by PFV vectors inhibit HIV-1 replication efficiently without cytotoxicity, with shRNA3 being the most effective. In addition, we analyzed the shRNA target sites in the 5′ LTR of HIV-1 strains other than HIV-1NL4-3 and found that these shRNAs may possibly inhibit other HIV-1 strains. © Mary Ann Liebert, Inc. 2015.
Chen X.,Wuhan University |
Zhang Y.,Wuhan University |
Shi Y.,Wuhan University |
Lian H.,Wuhan University |
And 10 more authors.
Oncotarget | Year: 2016
Abnormalities of autophagy have been implicated in an increasing number of human cancers, including glioma. To date, there is a wealth of evidence indicating that microRNAs (miRNAs) contribute significantly to autophagy in a variety of cancers. Previous studies have suggested that miR-129 functioned as an important inhibitor of the cell cycle and could promote the apoptosis of many cancer cell lines in vitro. Here, we reported that miR-129 acted as a potent inducer of autophagy. Forced expression of miR-129 could induce autophagic flux by targetedly suppressing Notch-1 in glioma cells. The autophagy induced by miR-129 could restrain the activity of mammalian target of rapamycin (mTOR) and upregulate Beclin-1. Moreover, we demonstrated that E2F transcription factor 7 (E2F7) could also trigger autophagic flux by upregulating Beclin-1 and mediating miR-129-induced autophagy. Additionally, knockdown of Notch-1 could upregulate the expression of E2F7, whereas downregulation of E2F7 alleviated shNotch-1-induced autophagic flux. In particular, knockdown of endogenous Beclin-1 could effectively reduce autophagic flux stimulated by miR-129 and E2F7. Interestingly, upon attenuation of miR-129- or E2F7-triggered autophagic flux rescued cell viability suppressed by them. More importantly, intratumoral injection of pHAGEmiR- 129 lentivirus in a nude mouse xenograft model significantly restrained tumor growth and triggered autophagy. In conclusion, these findings identify a new function for miR-129 as a potent inducer of autophagy through a novel Notch-1/E2F7/Beclin-1 axis in glioma.
PubMed | University of Lorraine, Wuhan University and Hubei Provincial Key Laboratory of Developmentally Originated Disease
Type: | Journal: Scientific reports | Year: 2015
Epidemiological evidence indicates that osteoarthritis (OA) and prenatal ethanol exposure (PEE) are both associated with low birth weight but possible causal interrelationships have not been investigated. To investigate the effects of PEE on the susceptibility to OA in adult rats that experienced intrauterine growth retardation (IUGR), and to explore potential intrauterine mechanisms, we established the rat model of IUGR by PEE and dexamethasone, and the female fetus and 24-week-old adult offspring subjected to strenuous running for 6 weeks were sacrificed. Knee joints were collected from fetuses and adult offspring for histochemistry, immunohistochemistry and qPCR assays. Histological analyses and the Mankin score revealed increased cartilage destruction and accelerated OA progression in adult offspring from the PEE group compared to the control group. Immunohistochemistry showed reduced expression of insulin-like growth factor-1 (IGF-1) signaling pathway components. Furthermore, fetuses in the PEE group experienced IUGR but exhibited a higher postnatal growth rate. The expression of many IGF-1 signaling components was downregulated, which coincided with reduced amounts of type II collagen in the epiphyseal cartilage of fetuses in the PEE group. These results suggest that PEE enhances the susceptibility to OA in female adult rat offspring by down-regulating IGF-1 signaling and retarding articular cartilage development.
PubMed | Wuhan University, French National Center for Scientific Research and Hubei Provincial Key Laboratory of Developmentally Originated Disease
Type: Journal Article | Journal: British journal of pharmacology | Year: 2016
Prenatal exposure to dexamethasone slows down fetal linear growth and bone mineralization but the regulatory mechanism remains unknown. Here we assessed how dexamethasone regulates bone development in the fetus.Dexamethasone (1mgkg(-1) day(-1) ) was injected subcutaneously every morning in pregnant rats from gestational day (GD)9 to GD20. Fetal femurs and tibias were harvested at GD20 for histological and gene expression analysis. Femurs of 12-week-old female offspring were harvested for microCT (CT) measurement. Primary chondrocytes were treated with dexamethasone (10, 50, 250 and 1000nM).Prenatal dexamethasone exposure resulted in accumulation of hypertrophic chondrocytes and delayed formation of the primary ossification centre in fetal long bone. The retardation was accompanied by reduced maturation of hypertrophic chondrocytes, decreased osteoclast number and down-regulated expression of osteocalcin and bone sialoprotein in long bone. In addition, the mitogen-inducible gene-6 (Mig6) and osteoprotegerin (OPG) expression were stimulated, and the receptor activator of NF-B ligand (RANKL) expression was repressed. Moreover, dexamethasone activated OPG and repressed RANKL expression in both primary chondrocytes and primary osteoblasts, and the knockdown of Mig6 abolished the effect of dexamethasone on OPG expression. Further, CT measurement showed loss of bone mass in femur of 12-week-old offspring with prenatal dexamethasone exposure.Prenatal dexamethasone exposure delays endochondral ossification by suppressing chondrocyte maturation and osteoclast differentiation, which may be partly mediated by Mig6 activation in bone. Bone development retardation in the fetus may be associated with reduced bone mass in later life.


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Choose from Three Options
- $59 for a haircut and style ($120 value)
- $89 for a balayage color treatment or highlights ($200 value)
- $149 for a keratin straightening treatment ($375 value)
E'lan Hair Salon
E'lan Hair Salon's stylists have extensive knowledge of both classic and cutting edge hairstyles. Specialties range from chic, pixie cuts and long-layered 'dos to sleek balayage color and keratin smoothing treatments. A chandelier and fresh flowers lend the salon an ambience that's just as upscale as its services.


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With only 89,000 minted, 1943 is the lowest mintage of the Gold 50 Pesos series, and the only issue from which the denomination was omitted and a legend indicating the metal content was duplicated in its place.
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A great value as well as a beautiful piece to behold.
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We provide all of our customers with a refund, return and / or exchange on everything we sell including all bullion and certified coins. If for any reason, you have a problem, please feel free to call us. We will always do our best to accommodate you.


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Ride to Redmond
Demystifying Vanpools
Vanpools are flexible, fast, for sure...and often FREE!
Take your vanpool a few times a week or every day!
Vanpools are flexible so you so you can:
- Take them a few times a week or every day
- Meet at convenient locations like park & rides or people's homes
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- Range in size from 5 to 15 riders
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Vanpools go direct and can take the HOV or Express Toll Lanes
Get to work more quickly in your vanpool.
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You have a ride home, even if something comes up & you can't vanpool home.
Take a free ride home in a taxi, Uber, or Lyft on days you vanpool if:
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Go Redmond pays $50 a month for your first year of vanpool fares!
See if vanpools are right for you by taking three free rides in any vanpool with the "Ticket to Ride."
Your monthly vanpool fare includes the gas, maintenance, and any tolls. They are based on:
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Address: 806 S Anteros Ave, Stockton, San Joaquin, California, 95215
Phone Number: 209-465-8687
Address: 806 S Anteros Ave, Stockton, San Joaquin, California, 95215
Phone Number: 209-465-8687
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Am I missing something?
Ok so I installed the basic player in order to test it out. I succesfully implimented a track into the database. I see the html5 player l;link on the left in my wordpress nav. How do I put it into a page or a post ? Iv studied and studied but cant work it out! Im sure Im just being dim!!! But its baffled me. Please help!!! Im very eager to actualy see the player ! Thanks. Baz.
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The Corner Pin - Town Pub of the Season
The beer – what other reason can there be for The Corner Pin gaining the Summer 2016 Pub of the Season award. Consistently good, a wide variety and happy faces both sides of the bar. Dave and Ruth put their heart and soul into keeping the pub at its peak and that's no easy task considering it's just outside the main centre of town.
Doncaster CAMRA's Pub of the Year in 2011, 2014 and 2015 is something of a statement when it comes to the appreciation of our members for this gem of a pub. 5 hand pumps that are usually in full use with an array of beers that are ever-changing to tempt you to try something different or go for an old favourite.
In April 2015 it was named as one of CAMRA's top 200 pubs nationwide and one of the top 16 in Yorkshire as part of the Community Pubs Month campaign, highlighting the important role pubs play in community life. There's certainly a diverse mix of customers who add character to the pub. There's a darts team led by landlord Dave who do battle weekly, a fun quiz every Sunday evening but with a lot of very serious contestants, and that's not to mention the food…
OK then, I will mention the food as Ruth's chip butties have become a thing of legend with visiting CAMRA branches writing about them, community groups who meet there insisting on them, and that's only one item on the menu. I'm one who actually prefers eating here to many of the other pubs around. Everything is prepared on the premises. No reheated freezer mush or skinny fries.
A very popular Sunday lunch venue too. It's all freshly made and it's wise to book in advance or you'll probably not get a place. During the rest of the week Ruth does an excellent fry-up, amongst other things, but check that the kitchen is open before you visit mid-week as she does need some time off to go get the shopping.
Another tick on the CAMRA great pub list is gained by the use of lined glasses, pints and halves, for the real ale on offer. For those who insist on the fizzy cold stuff there's also a range of lagers and keg beers to be had. It's a traditional bar with a wooden floor and has loads of character.
At the time of writing, Leeds Pale and Stancill Barnsley Bitter were the regular real ales, leaving three pumps to be filled by guests. If you find a guest beer you like then make the best of it as once it's gone it could be some time before it appears here again, unlike some pubs whose 'guest' beers stay the same week after week.
I travel to many places for beer festivals or just a day with friends but always enjoy coming back to the Corner Pin.
Shoulder of Mutton, Kirk Smeaton - District Pub of the Season
Not for the first time has the Shoulder of Mutton been awarded the District Pub of the Season following a popular vote by members of Doncaster and District CAMRA. It has previously won the award in Autumn 2011 and prior to that in Winter 2005/06. Also in 2007 it was voted District Pub of the Year. Congratulations are therefore in order, again, to Christine Sanderson, the longserving manager and her staff for continuing to serve quality real ale. Two real ales are always available on the bar. The first, the regular beer for many years, is Black Sheep Best Bitter delivered direct from the brewery. A fact that no doubt contributes to the excellent condition in which the beer is always to be found. The second, a guest beer, currently Theakston Best Bitter, has over the years been provided by breweries as varied as Old Mill, Wharfe Bank and Dark Horse from Hetton in North Yorkshire.
At one time a Whitbread house, the pub was purchased free of tie many years ago by two local businessman who wanted to ensure that the village retained a working pub at the heart of the community. Located in the centre of the village, the pub comprises a small oakpanelled lounge and a somewhat larger and more popular public bar area, both served from a single central bar. It has a large car park and a substantial beer garden in which is to be found a covered and heated smoking shelter. An additional outside seating area is also available. Although no hot food service is provided a range of freshly-made sandwiches are available at the bar.
In addition to the quality ale, what really makes this pub stand out is that it offers a fine example of what a good traditional village pub should be. It serves as a hub for the community that is the village of Kirk Smeaton. It's a very friendly pub. Whether you're eighteen or eighty, a local born and bred or an incomer to the village or indeed just passing through the village, the pub is very welcoming. As in any good pub there's usually a conversation to be had with someone from among the diverse group of drinkers to be found at the bar. Walkers are also welcome, with the pub offering an ideal start and end point for several circular walks of varying length in and around the area of the Went Valley and Brockadale Nature Reserve. A quiz is held every Tuesday evening.
Essentially the Shoulder of Mutton is what I and, I suspect, many other drinkers think of, as a great example of what a good local pub should be. It's also, regrettably, an example of a type and style of pub that is slowly disappearing from national life


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I got to meet Dr. Jerry Buss and his daughter Jeanie when they returned to Los Angeles from Hawaii. I didn't get a chance to really talk to them very much, but I did make sure that other paparazzi kept away…he was doing his best to keep his trip with his daughter a bit more private.
While Jerry is most famous for being the owner of the Lakers, he also had his hand in the Los Angeles Kings in hockey and the Los Angeles Sparks in the WNBA, and Los Angeles Lazers soccer team. As an official doctor, his PhD in physical chemistry came from the University in Wyoming. Now he could also be considered a doctor of poker, having ranked really well in many poker championships.
His beautiful daughter Jeanie is now a vice president covering business operations with the Lakers. She had gained some popularity after posing for Playboy, but she is now romantically linked with the Lakers' coach Phil Jackson. I guess she never did have a taste for short guys, darn it all.


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emma watson love eco friendly beauty products, essentials
Emma watson eco friendly beauty essentials
Emma Watson's love of ethical and eco-friendly products doesn't only apply to her wardrobe, but her make-up too. The Beauty and the Beast star has been educating fans about her sustainable style choices throughout the promotional tour for the film, and also revealed which beauty products she used to create her stunning look for a screening in London's Leicester Square on Thursday evening.
GALLERY: Emma Watson's ethical Beauty and the Beast press tour wardrobe – all the looks
Taking to her new Instagram account to share a photo of herself in her bespoke Emilia Wickstead gown, Emma gave a breakdown of the products she had used – and also why she supported those brands. To prep the skin, Emma started with de Mamiel Skin Dewy Facial Mist (£47), which she explains is "made from ingredients sourced and blended in the UK, in small batches to maintain the vitality of each natural ingredient".
Emma Watson revealed the beauty products she used ahead of the Beauty and the Beast screening
This was followed by repairative moisturiser from Tata Harper (£84), a brand that is "verified by PETA that neither the brand nor its ingredient suppliers conduct, commission, or pay for any tests on animals for ingredients, formulations, or finished products". Decléor Aromessence Neroli Hydrating Oil Serum (£46), was also applied to Emma's skin before her make-up. "Decléor serum is a blend of naturally derived ingredients such as neroli and sandalwood and free from mineral oils and parabens," Emma explained on Instagram.
STORY: Did you spot the Harry Potter reference in the new Beauty and the Beast clip?
Emma opted for a stripped-back make-up look to complement her elegant gown, and used Inika Organic BB cream (£23.38) as her base. The BB cream is "certified organic, vegan and not tested on animals," Emma said, while her RMS Beauty 'Un' Cover-Up concealer (£28) is made from organic coconut, jojoba and cacao oil and mineral colours.
The Harry Potter actress uses eco-friendly and natural beauty products
The 26-year-old added a pop of colour to her cheeks with Ilia multi-stick (£30) in A Fine Romance, while Inika's Mineral Mattifying Powder (£21) – blended from "silica, corn, tapioca and rice powders instead of talc" – completed the look.
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