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WebSphere Migration Assist Program - Information on participation
27PS_Michael_Hill Tags: migration ma migrate was upgrade websphere websphere_application_ser... 1 Comment 5,042 Views
Have you ever wanted to know about WebSphere Application Server (WAS) migration Best Practices and have a technical lead guide you through the process? It's here. IBM Support is pleased to offer our clients Migration Assist (MA). MA is provided by...Modified on by SteveWebb
CHLAUTH feature in MQ 7.1
The new channel authentication records were added to version 7.1 to give more precise control over access granted to a connecting system at the channel level. This feature allows you to define rules about whether certain inbound channels to a queue manager...
WebSphere / IBM MQ Migration Guide
Jason Simmons Tags: planning migration installing upgrade ibmmq migrate install mq upgrading wmq plan 2 Comments 15,213 Views
The WebSphere / IBM MQ Self-help Migration Guide is designed to help users choose, plan, and simplify the process of migrating from an older version of MQ to a new version. If you are running z/OS, see our related blog entry WebSphere / IBM MQ for z/OS...Modified on by Jason Simmons
WebSphere / IBM MQ for z/OS Migration Guide
Beverly Brown Tags: upgrade zos plan planning install wmq installing z/os migrate migration upgrading ibmmq mq 8 Comments 8,661 Views
Like the WebSphere / IBM MQ Migration Guide for distributed platforms , the WebSphere / IBM MQ for z/OS Self-help Migration Guide is designed to help users choose, plan, and simplify the process of migrating from...Modified on by SteveWebb
What's the talk about in WebSphere Message Broker? (Part 2)
Gregory(Greg)Bowman Tags: availability encoding wmq ha websphere db mq message migrate install migration services installation xml broker wmb web ssl migrating certificate database high 10,768 Views
I wrote a blog article a while ago entitled " What's the talk about in WebSphere Message Broker? " Several months have passed and now people are discussing some different topics in WebSphere Message Broker (WMB) support. So I thought it was time to...
Simplify Your Product Migration using the Dynamic Migration Guides
SteveWebb Tags: was websphere_application_ser... dx wmb migrate index iib experience migration wmq websphere portal ibmmq broker mq digital upgrade upgrading guide ibm-integration-bus 1 Comment 6,188 Views
We have recently published several Self-help / Dynamic Migration guides for various products. These guides are designed to help users choose, plan and simplify the process of migrating from an older version to a more current version of each product....Modified on by SteveWebb
Migration: Moving to WebSphere Message Broker V7 land
Ever since the end of support date for WebSphere Message Broker (WMB) V6.0 was announced, we have been receiving a lot of queries on migration from the older versions of Message Broker to the latest WMB V7.0. In this blog, I have tried to address some common...
Do you need to migrate from old unsupported WebSphere MQ version 5.3?
ValerieLampkin Tags: listener migration 7.5 installation upgrade websphere runmqlsr mq 5.3 7.1 7.0.1 wmq install migrate 8,723 Views
I've had a few customers lately that are in a situation where they are still running old unsupported versions of WebSphere MQ. Specifically, a problem arises when they are still on MQ version 5.3 and want to upgrade to a recent version such as 7.1 or 7.5 as...
What's Hot in the WebSphere MQ World? (Part 2)
Gregory(Greg)Bowman Tags: of mqrc_not_authorized 2035 authority eos flash downloads client ic72897 support announcement extended xtc wmq auth transactional migration jms end migrate alert security mq authorization websphere 13,450 Views
Earlier in the year I wrote an article talking about the hot topics in WebSphere MQ (WMQ). I thought now would be a good time to take another look and see what has changed. I found a lot of the things that were hot then are still hot now. So in this article,...
ITCAM for Transactions - How to upgrade RPT? Community Blog
ericmtn Tags: itcam itcamfortx performance itcam4tx migrate migration hdt15 rpt tester upgrade rational 737 Views
If you are currently using Rational Performance Tester (RPT) v8.2 and are encountering an issue with it, you need to know that RPTv8.2 is out of support, since 30 Apr 2016 , as seen below :...
Migrating WebSphere MQ Isn't Something That Should Go South
MarkWomack Tags: mqseries migration migrate websphere coexistence fallback mq upgrade installation wmq 6,815 Views
Most migrations (upgrades) of WebSphere MQ go swimmingly, don't they? This is a good thing. But we'd like to see every single one of them fall into that bucket. To that end, it's crucial that you include the following information into your migration plans....
Migrate-import and restoring the TEPS database. Community Blog
sandrajones Tags: monitoring migrate ibm sandrajones monitoringacademy backup itm restore import hdt15 4,953 Views
So the previous blog detailed the steps on how to take the export of your TEPS but it is only useful if you know what to do to restore it on your original or another TEPS. This is what this blog will discuss. There are some requirements...Modified on by sandrajones
WebSphere MQ for z/OS Version 8: New Toys In the Box!
MarkWomack Tags: coexistence websphere z/os wmq v8 systemz caf migrate upgrade mq migration 2 Comments 8,954 Views
It's the moment you've all been waiting for (I know I have). Version 8 of WebSphere MQ has been announced and will soon officially become available for the z/OS platform (General Availability date 13 June for z/OS, eGA of 23 May for...Modified on by SteveWebb
Thinking about upgrading, migrating, applying maintenance on UNIX?
ErikKirk Tags: broker libpath profile problems migrate wmb maintenance export migrating migration upgrading upgrade 5,261 Views
Thinking about upgrading, migrating, applying maintenance on UNIX tm ? How about 1 minute sanity check of your environment? Problems often occur during or after an upgrade, migration, or application of maintenance. If you have bad luck, there's a good chance...
Your IBM Operational Decision Manager application lifecycle
LaurentTCT Tags: migrate upgrade maintenance jrules fixpack fix odm update 4,734 Views
Once your application is implemented and deployed, it is important to keep it up-to-date and maintained to avoid any issues that might impact its availability and to ensure continued support in the event a problem occurs. The Operational Decision...Modified on by SteveWebb
Migrating from JRules to WebSphere Operational Decision Management (WODM)
It is always recommended to use the latest available version to benefit from the latest released features. For instructions to install, see Installing WebSphere Operational Decision Management (WODM) V7.5 and WebSphere Operational Decision Management V8.0...
Lotus Notes в "яблоках" Community Blog
Итак, вы специалист по Lotus Notes/Domino и у вас все хорошо. Прошли времена борьбы с "инсталяторами" на Linux, миграция с версию на версию делается с закрытыми глазами, файл notes.ini - открытая книга, а в арсенале всегда имеется парочка не...
from Blog: Lotus.RU
Installing WebSphere Operational Decision Management (WODM)
The launchpad, introduced in V7.5, helps you install the prerequisites and the product components, in the correct order. To understand the WODM components that the installer includes, read the section Composition of Operational Decision Management for version...
What's the talk about in WebSphere Message Broker? (Part 3)
Gregory(Greg)Bowman Tags: eos broker iib migrate websphere ibm migration wmb faq end integration bus support message frequently asked of questions 9,171 Views
There has been a lot going on in the WebSphere Message Broker (WMB) world since the last time I wrote about the hot topics that have people talking. All this activity makes WebSphere Message Broker an exciting and busy place to be and it gives people...Modified on by SteveWebb
Sizing recommendations for planning migration of data from Rational DOORS to Rational DOORS Next Generation
paulellis Tags: supce limit ibm-iot import migration dng ibm-doors rdng ibm-doors-ng iot-support migrate 3,472 Views
Are you considering migrating your data from Rational DOORS to Rational DOORS Next Generation(RDNG)? Are you looking for guidance and best practice before you begin to be successful first time? If so, then your starting point is definitely the...
from Blog: Notes from IoT SupportModified on by dmmckinn
Migrate-export and backing up your TEPS database. Community Blog
sandrajones Tags: ibm itm snd45jns monitoringacademy migrate hdt15 5,444 Views
Something that you should think of doing on a regular basis is to take a backup of the TEPS database. This will allow you to move the TEPS to a new machine, or restore...Modified on by sandrajones
How to resolve "SQL0204N 'TMPBP32K' is an undefined name" during upgrading the MONITOR database
Yan Fang Tags: sql0204n upgrading migration migrate websphere business_monitor monitor upgrade bpm business tmpbp32k 5,177 Views
Migrating refers to the process of moving applications and configuration information from an earlier version of a product to a later version of the product, or from one product to a different product. Upgrading refers to the process of installing a new...Modified on by SteveWebb
Part 3: Migrating from IBM Business Process Manager Standard V7.5.x to V8.0
This blog is split into the following 3 parts to keep it simple and compact: Part 1: Migrating from IBM Business Process Manager Version 7.5 to 8.0 Part 2: Migrating from IBM Business Process Manager Version 7.5 to 8.0 Part 3: Migrating from IBM Business...
This week's developerWorks newsletter intro: DB2 migration in no time Community Blog
John Swanson Tags: developerworks introduction migrate db2 newsletter intro oracle enablement 2,886 Views
This week's developerWorks newsletter shows you how easy it is to make the move to DB2. Not subscribed? Sign up for your customized newsletter today! ************************ Welcome, developers! OK, no more excuses. If you've considered making the move...
from Blog: developerWorks enthusiasts
Part 1: Migrating from IBM Business Process Manager Standard V7.5.x to V8.0
This blog is split into the following 3 parts to keep it simple and compact: Part 1: Migrating from IBM Business Process Manager Version 7.5 to 8.0 Part 2: Migrating from IBM Business Process Manager Version 7.5 to 8.0 Part 3: Migrating from IBM Business...


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A bidet shower (bidet spray, bidet sprayer, or health faucet, sometimes colloquially called a Muslim shower (because it is customary for them to clean themselves), or a "bum gun", is a hand-held triggered nozzle, similar to that on a kitchen sink sprayer, that delivers a spray of water to assist in anal cleansing and cleaning the genitals after defecation and urination.
The health faucet is a source of water for people who prefer using water rather than other methods of cleansing after defecation or urination. The bidet shower is a relatively modern replacement for the traditional sources of water for this action, such as the bidet, copper pot or bucket and mug, being more hygienic and compact. There is no contact between the spray of water and the used water drainage.
Typical faucet installation
Faucet close up
A Finnish model, manufactured by Oras
A bidet shower at the Waldorf Astoria New York
The user typically grasps the faucet in the right hand and uses the thumb or forefinger (depending on the trigger location) to aim a spray of water at the anus or genitals, sometimes using the left hand (never the right hand in many cultures) or toilet paper to assist cleansing. It is a custom among Muslims to cleanse themselves with water in order to be clean, in the Muslim world, and specially in Asia, where water is commonly used instead of or together with toilet paper for cleaning after defecation.
The bidet shower is common in all predominantly Islamic countries and in most parts of Asia where water is considered essential for anal cleansing. This includes Nepal, Pakistan, China, Iran, India, Bangladesh, Turkey, Iran, United Arab Emirates, Indonesia, Malaysia, Philippines, Sri Lanka, Thailand, Singapore, Vietnam and Cambodia. In those countries it is commonly installed in Western-style (sitting) toilet installations. In Thailand, it is common in both Western-style toilets and squat toilet installations. The bidet shower is similar in intent (if not method of use) to the Japanese washlet-style toilet seats, or so-called "electronic bidets".
In Europe, it is used for example in Finland, while bidets are more common bathroom fixtures in many southern European countries. It is very common in Brazil, where traditional bidets are being replaced by it. It is most common in Muslim countries and all parts of the Arab world.
When served a beverage, accept with the RIGHT HAND ONLY! When eating, drinking, offering, or passing use right hand only! ... When eating with Arabs, especially when taking food from communal dishes, the left hand must never be used, it is considered unclean.

subset: commoncrawl


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What Keyboard Tracer Does
Näppäimistö merkkiaineen scrupulously and patiently records everything pressed and typed on the keyboard plus provides a number of additional forensics functions useful both at home and in the office.
The program can work silently and invisibly providing you with a reliable intelligence report on what is going on on your computer during your absence.
The latest version features automatic screen snapshots at stated intervals to give you not only textual but also visual control over the computer. And the text input is also enhanced in the latest release: Keyboard Tracer now logs all text copied to the Clipboard.[Lue lisää] [Lataa] [Tilaa nyt]


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The funny marriage videos below will provide some practical advice. More importantly, they will make you laugh about your marriage and relationship. This something we all need to do more often….Laugh, Love and take a Chill Pill for a long successful marriage.
How About Some More Funny Marriage Videos and Quotes?
Remember…Keep on laughing and enjoying your marriage. Marriage should be joyful most of the time, but unfortunately, many couples focus on the struggles in their marriage and not on the pleasures. You need to change that pattern starting today!
August 29, 2016


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Family parties can be potential dynamite but not the one we attended in Maiden Newton recently. The closest we got to dynamite was the splendid tree candle which Andrew had carefully fashioned as a finale for the party that was held to honour the centenary of Nick's father's birthday.
He got the idea from Walter when we were up at Inshriach at Easter. You get a suitable length of tree trunk and split the upper part criss-cross (with a chainsaw ideally) sufficient to stuff a firelighter within. Then you set light to it. Fascinating to watch the progress and pattern of burning.
Maddy's party, carefully planned, was hugely enjoyed. Some family members endured long journeys in order to converge for the celebration. This was a party for Dick Light's descendants and their partners. Maddy is the family's genealogist and archivist and had collated as much as we all could extract from our mementoes and photograph albums. Young and not-so-young took turns at the computer screen whilst Powerpoint scrolled its way through the text and photos that tell Dick's story. Subsequent Facebook albums will add to that archive.
A Light party would not be complete without some turns of Croquet and a session of 'Scottish dancing'. Henry had organised an ingenious 'cache' hunt in which the children delighted. By the kind offices of Nel and Elisabeth the solitary egg produced by the hens that Saturday was recycled many times to give the children the endless pleasure of retrieving eggs from the straw in the henhouse.
I couldn't help reflecting that it does not seem a married lifetime ago that I first participated in a Light/Edwards clan gathering. Then, aged 17 or so, I was only 7 years older than my eldest grandson. I thought they were a pretty fun lot and just a bit outré. My flame-haired mother-in-law was awesome and I was always a bit frightened of her. But I was not alone and at her funeral one of her sons remarked that she had been an amazing mother but perhaps less gifted as an 'in-law'.
Dick by contrast I remember as a quieter, peaceable character who was robbed of most of the years he hoped to have in retirement. But his genetic inheritance was spread about the 40 or so of us who relaxed in the sunshine on his special remembrance day.


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Back Pain Relief For Pain Free Living
Anyone who has ever suffered from or is currently experiencing back pain knows just how much it can debilitate you. The pain prevents you from moving like normal. This can be frightening, so understanding how to avoid back trouble is important. Follow these tips to achieve this goal.
Medical doctors are more likely these day to work side by side with alternative practitioners. Therefore, it is important to ensure that your insurance provider offers coverage for alternative therapists like a chiropractor or acupuncturist. This type of service will enhance physician care.
Don't think you're...


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The national postal service came out Wednesday with a stamp honoring the first Latin American pope, Francis, on his first year in office.
The pontiff, who is from Argentina, is called Francisco in Spanish. The stamp is valued at 300 colons, about 56 U.S. cents.
Like many of the commemorative issues by Correos de Costa Rica, the graphic is from an oil painting. The artist is Juan Manuel Delgado Méndez. Printing was by the La Uruca firm Imprenta Gozaka S.A.
The stamp is available at the downtown main postal office and also online at the Correos Web site.


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So I used to think that I was semi-useless, and that to do interesting real-life things, I would have to find someone willing to work with me.
Cue madness and dysfunction, and then repeat.
George Shaw said something once about how an eye doctor told him that he had nearly perfect vision, and that most people actually didn't have what we think of as normal sight, because they saw with some percentage of distortion. He also said that he, in his younger days, invested a massive amount of time in finding out if he was wrong about things, and that he gradually came to the understanding, as the years passed, that he had always been right about everything, the inference being that his ideal vision led him to see things as they actually were.
Shaw also thought he was better than Shakespeare, but Shaw didn't understand love, and made a positive old fool out of himself over ladies. Sadly, Chesterton is correct, and John Bull's Other Island is the only decent play that Shaw ever wrote. All of Shaw's other plays demonize and dissect romanticized love in an absurd fashion that reveals his pathological fear of beautiful women.
The point being, Shaw saw things as they really were, but his obsession with avoiding his damaged childhood made him into a fool in the long run.
I also see things as they really are, and I don't want to make a fool out of myself.
There's a long gap of nine years where no one knows what William Shakespeare was doing with himself. A lot of educated people have pet theories about different mystery occupations the soon-to-be established playwright was engaged in during those nine years.
But I'll tell you what the Bard of Avon was doing during those nine years; he was doing what Shaw never had the sense, the guts, or perhaps the good fortune to do. Shakespeare was working through his personal issues.
And that's what I'm doing right now.
I keep reminding myself of how worthwhile it will be to not have neurotic pathology rampaging through my day. Because telling myself that feels like it will make the pain worthwhile somehow.
I think it's funny to read therapy books by counselors who have clearly never formed a real understanding of the pathology of the victim. They bluster and preach, and they have useful things to say, but they sound like emotional dunderheads while they say them. And often, selfishness and abuse and rationalizing the abuse filters through.
I don't know why my abuse was worse than anyone else's, but it was. I was very smart, and in some ways my abusers were afraid of me, because I saw them more clearly than anyone else did. I protected myself from a lot of physical things that could have happened. And it isn't exactly that my abusers were creative, or original; it was that I fully experienced the abuse as a conscious entity while all of it happened. And most people hide.
Anyway, decent humans don't work well as business partners with indecent humans. I had to run through about twelve different partners and potential partners before the pattern of corruption became very clear. They all wanted my power; none of them wanted to suffer to earn it. All of them were different, too. They had different ways of lying. I thought a few of them were really decent people, until time showed their willingness to deceive and cheat and steal.
The worst were the people who wanted to tinker with bodies, the way I did. None of them ever found out how, because I didn't trust any of them, but they all wanted to know how to push people's buttons. They were all trying to hack into some kind of parlor trick that would let them open up people's hearts, the way I did. They couldn't see that it wasn't me doing the opening up. People open up themselves when they feel comfortable, loved, and safe. And abusers can't make anyone feel genuinely loved and safe; they're constitutionally incapable.
In other news, I am thinking about buying breakfast cereal.
Happy writing.


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I wrote about how Drake became our biggest pop star for the Irish Independent, read it here.
Monthly Archives: February 2017
1 Thing: January and February's R&B
My first R&B column for the Quietus can be found here.
(Photo by James W Mataitis Bailey)
Sampha – 'Process'
I reviewed Sampha's debut album Process over at the Quietus, here.
December and January's Hip Hop Reviewed
I've taken over the hip hop column at the Quietus, and will also be doing an R&B column every other month for them. My first hip hop round-up, looking at releases from December and January, is here.


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«NEW» - Free Made in Japan : Akio Morita and Sony Ebook Download Full
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All American Christmas Company is gearing up for the upcoming holiday season by accepting early orders on all of their Christmas Lights. Full details are available online at http://www.aachristmas.com.
Sparta, Tennessee (PRWEB) September 03, 2013
Because it's never too early to start planning for the Christmas holiday season and Christmas lighting displays, All American Christmas Company is now accepting early orders for the upcoming holiday season. All American Christmas Company is the leading source to turn to for the most extensive selection of Christmas lights and other decorations. As summer winds down, All American Christmas Company is just beginning to gear up for its annual rush of residential and commercial customers who will soon be making preparations for the upcoming holiday season.
While Christmas is the focal point of their business, All American is also the leading source for all major holidays, including Halloween and Thanksgiving decorations and lighting displays, so they anticipate another busy fall season before their crushing annual Christmas rush. Even with the Christmas season a few months away, savvy holiday lighting shoppers know to plan far in advance while supplies are plentiful in order to claim bragging rights for having the most eye-catching displays in their neighborhoods, store and business sites, and or community locations.
All American Christmas Company is making shopping early even more rewarding with 10 percent discounts for orders of $40 or more placed online at aachristmas.com, using the promotion code save10. The discount can be used on All American Christmas Company's thousands of products, which include virtually every type of Christmas lighting imaginable, particularly the most popular varieties of small Christmas lights, and LED Christmas lights.
All American Christmas Company has developed a well-deserved reputation as the leading source for all types and sizes of Christmas lighting products, such as C7 and C9 light bulbs, Christmas light strings, globe lights, and all other lighting products, including all sizes of energy saving LED Christmas lights through its 15 years of service to consumer and commercial customers as well as civic and public organizations.
All American Christmas Company's light products are used to create sparkling displays to fit all budgets and desired effects, from the individual home owner looking to have the biggest and brightest display on the block to businesses looking to create dazzling, customer pleasing memorable lighting displays. In addition to boasting one of the largest inventories of holiday lighting products, All American Christmas Company also is known for its affordable prices and outstanding customer service and planning suggestions.
The All American staff has been helping customers create memorable displays for a quarter of a century and is always happy to assist its clients and encourages them to take advantage of their hands-on planning assistance. All American's staff of experienced lighting and display professionals can recommend the best solutions for any lighting project, including recommending the proper amount of lights and the most appropriate selection of lights needed to cover the desired surfaces.
All American Christmas Company's expertise is available for all customers, large or small, and the lighting experts can always be counted on to treat all orders with equal attention. They eagerly assist individual homeowners or small businesses select the most appropriate products to fit their budgets with the same attention they extend as one of the premier suppliers and designers of commercial holiday light displays for thousands of organizations, businesses, and municipal groups across the nation. All American's lighting displays have been used to create festive displays for venues such as Universal Studios Florida, the Reno-Hilton, Martha Stewart Living, Radisson Hotels, the Minneapolis Convention Center, Marriott Frenchman's Reef, Harvard University, Great American Restaurants, CBS This Morning, Brown University, Beverly Hills Restaurant, the Alabama Shakespeare Festival, and several military installations, to name just a small sample of their satisfied customers.
All American's scope goes far beyond festive holiday lighting and displays. The company is also a popular choice for special occasions such as weddings, private parties, proms and formal dances, corporate events, retail displays, and shopping center and business' special lighting effects. They can make any venue a festive, special scene for a memorable event with their unmatched designing and lighting services.
All American Christmas Company's full line of products and services are presented year round online at aachristmas.com. Experienced service representatives are always ready to answer questions, to provide planning and designing advice, and to help place orders by phone at (931) 836-1212. All American receives fax inquiries and orders at (931) 836-2002.


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Please note that the address for this place is approximate. Upon booking a stay, the rental owner will provide an exact address. Accept no compromises! Enjoy your vacation within Provincetown's finest beachside residence. Comprising the entire MAIN FLOOR of Provincetown's landmark Sandpiper Beach House, this exceptionally fine home uniquely combines spectacular waterside v... Child's Highchair, Dining, Dining Room, Books, Books for Adults, CD Player, DVD Player, Games, Games for Kids, Music Library, Radio, Satellite / Cable, Stereo, Television, Toys, VCR, Video Library, Activities Guide, Air Conditioning, Alarm Clock, Basic Soaps, Broadband Access, Ceiling Fans, Clothes Dryer, Free Long Distance, Hair Dryer, Heating, Internet, Iron & Board, Laundry Soap, Linens Provided, Living Room, Local Activities Guide, Local Maps, Local Restaurant Guide, Paper Towels, Parking, Parking Off Street, Parking for RV/Boat/Trailer, Shampoo, Sofa Bed, Telephone, Telescope, Thermos Bottle, Toilet Paper, Towels Provided, Washing Machine, Wireless Internet, Blender, Catering Available, Coffee Grinder, Coffee Maker, Cooking Utensils, Dishes & Utensils, Dishwasher, Freezer, Grill, Ice Maker, Kitchen, Lobster Pot, Microwave, Oven, Pantry Items, Refrigerator, Stove, Stove, Toaster, Staff, Balcony, Barbecue, Beach Chairs, Beach Towels, Bicycles, Boat, Deck / Patio, Deck Furniture, Golf, Kayak / Canoe, Lanai / Gazebo, Lawn / Garden, Outdoor Grill, Outdoor Grill Gas, Porch / Veranda, Terrace, Unscreened Porch / Veranda, Walkway to Water, Wood Deck, condo, Long-term Renters Welcome, Low Allergen Environment, alternative lifestyle, children welcome, limited accessibility, non smoking only, pets considered, suitable for elderly or infirm, Adventure, Away From It All, Family, Historic, Romantic, Sports & Activities, Tourist Attractions, house, Guests provide their own meals, Housekeeper Included, condo, autumn foliage, bay/sound, churches, cinemas, forests, health/beauty spa, library, live theater, marina, museums, nude beach, playground, pond, restaurants, water parks, winery tours, not necessary, antiquing, beachcombing, bird watching, boating, eco tourism, paddle boating, scenic drives, shelling, shopping, sight seeing, walking, whale watching, Beach, Beach View, Beachfront, Downtown, Ocean View, Oceanfront, Town, Water View, Waterfront, ATM/bank, Babysitter, fitness center, groceries, massage therapist, medical services, cycling, deepsea fishing, fishing, freshwater fishing, golf, golf privileges optional, hiking, jet skiing, kayaking, mountain biking, pier fishing, sailing, snorkeling, sound/bay fishing, surf fishing, surfing, swimming, tennis, water skiing, wind-surfing
The Ultimate Beach House & Provincetown Center - Pet Friendly
Provincetown, Massachusetts 02657 USA
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- 02:09
- 75 mi.


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The FA's Non-League Finals at Wembley Stadium
The FA's Non-League Finals Day is returning to Wembley Stadium on Sunday 21 May 2017.
Venue Details & Map
Wembley Stadium
- Address
Olympic WayWembleyLondonHA9 0WS
- Telephone:
- +44 (0)20 8795 9000
- Public transport:
- The nearest tube station is Wembley Park (Jubilee and Metropolitan lines). The nearest railway station is Wembley Stadium. Download the Wembley App for latest travel information


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We booked in for two nights towards the end of a road trip L.A. to S.F. via Yosemite. Without doubt this was the most impressive accommodation of our trip. A fantastic suite just above the main lodge. As well as the very impressive room we found everything else at the ranch to be top quality, great food, friendly staff and efficient service. I can highly recommend the Bee experience whether you think you would like this or not. I booked it after reading other reviews, certainly not because I had any particular interest in it specifically. I was so very glad we did, absolutely fascinating. The kids pool was also impressive with a nice big pool and hot tub, nice cafe, places to just relax in the sun, tennis courts and basketball hoops, a very well equipped gym and nice changing rooms. Despite the five star nature of the place the owners have managed to create a very relaxed and informal environment that feels very comfortable and inclusive, I fail to see how anybody would regret booking this place.
- Official Description (provided by the hotel):
- Stunning and relaxing, our elegant Carmel Valley resort is abundant with the natural beauty of Northern California, offering intuitive service and memorable experiences in a striking venue. Savor incomparable comfort, breathtaking vistas, and a delightful array of activities at Carmel Valley Ranch. ... more less
- Reservation Options:
- TripAdvisor is proud to partner with Travelocity, Orbitz, Expedia, Priceline, Hotels.com, Prestigia, Booking.com, Cancelon, Hotwire, TripOnline SA, getaroom.com and HotelQuickly so you can book your Carmel Valley Ranch reservations with confidence. We help millions of travelers each month to find the perfect hotel for both vacation and business trips, always with the best discounts and special offers.
- Also Known As:
- Carmel Valley Ranch Hotel Carmel
- Carmel Valley Hotel
- Carmel Valley Resort


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NURSES' RESPONSIBILITY in the Prevention of Medication Errors.
NURSES' RESPONSIBILITY in the Prevention of Medication Errors. - Assignment Example
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NURSES' RESPONSIBILITY in the Prevention of Medication Errors.
''The problem of medication errors can be avoided only when the nurses take a keen interest on their jobs by being highly skilled in their profession'' (Joint Commission Resources, Inc. 2001, 13). Nurses Responsibility in the Prevention of Medication Errors Have you ever imagined a world where there are no nurses? Individuals would be succumbing to deaths from various causes like injuries to sickness. Nurses' role can never be underestimated as they play a significant part in saving lives in both public and hospital hospitals since in most cases medication errors leads to ''complex sorrows'' (Cohen, 2007, 50). This essay discusses nurses' responsibility in the prevention of medications errors. One of the duties of a nurse is the administration of drugs. Even when the other processes of treatment have been properly completed, wrong administration of drugs can lead to serious problems to the patient. ''Some of the worst medication errors involve some of the best and experienced practitioners'' (Cohen, 2007, 49) It is therefore necessary for the nurse to ensure that the drugs reach the patient through the correct route. ...
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The Nurse?s Responsibility in the Prevention of Medication Errors Student's Name and Last Name Management Resources Institute Professor Ismary Ruiz ENC1101 Final Research Paper Date: Abstract Nursing is a wide subject that involves multiple specialties varies in the different countries found within the planet…
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Title: Thanks Tinnu for all your help and support
Post by: Morlocrond on September 24, 2009, 08:11:37 AM
Well for a casual type gamer like myself. I use casual loosely so as not to start an argument. I made it to a mile stone, that for me is a great achievement. I entered the serene forests of Lorien last night for the first time. Haven't made enough rep to enter the city yet, but all in due time.
I wish to thank all the Tinnu members on being so helpful, kind, patient, etc, etc,...( i could go on and on). This guild makes it real easy to play lotro thats in a game genre that no matter what you, will always end up "grinding" something for something. So here is to Tinnu for all the help and support in the past and future that helps increase the enjoyment of an already enjoyable game.
I thank you.
PS. Sorry if i posted this in the wrong section.
Title: Re: Thanks Tinnu for all your help and support
Post by: Orophor on September 24, 2009, 01:04:47 PM
Thank you for sharing your gratitude with the kinship Morlocrond. I too am grateful for the fine fellowship of our kin. The understanding and support we share for one another is a true gift, freely given and joyously received.
Congratulations on making it to Lorien. Once you have earned the trust of Lord Celeborn and Lady Galadriel, you may take refuge in Lothlorien to rest before we march off to Mirkwood and the pace of war quickens.
Though our road ahead is a dark one, there we must go. For what small hope we have is in standing fast against the Dark Lord. As I promised Master Goodsong, we shall one day picnic before the Black Gates. I am pledged to bring an army, whilst he shall bring the food.
Title: Re: Thanks Tinnu for all your help and support
Post by: Harmonii on September 24, 2009, 04:14:53 PM
I agree with you whole-heartidly, this kin has a flame kindled inside of it, and I've never felt more at ease around a group of people, online or in rl, they really are a superb bunch, and we are blessed to have them as family. I look forward to the long march to mirkwood with those i care about, and relish the thought of eating Master Goodsong's excellent gourmet feast at the Black Gates. I miss you all, and hope to see you soon!
Harmonii Moonchylde
Title: Re: Thanks Tinnu for all your help and support
Post by: Morlocrond on September 25, 2009, 05:55:39 AM
I'd be happy to be the rear guard for the march to Mirkwood. I would be brash and say I will be the vanguard, but as many well know your horses would out run me. ;) (I own not one horse. Its a long story. :) )
And now that I read what I wrote yesterday I do apologize for the bad grammar. I am dreadful at grammar of any sort.
Title: Re: Thanks Tinnu for all your help and support
Post by: Digger on September 29, 2009, 03:52:13 PM
Since the first day I left the Shire and joined this kinship, I have felt this spirit that the good people have about each other and about the kinship, itself. I attribute much of it to the inspiring non-leading leadership that our Tur brings us and the few but meaningful values he has instilled in every one of us. Thoughts like 'RL always trumps VL' and 'No oath binds us' and 'Let each enjoy the game in their own way' along with several others, have truly made a huge difference in our feelings towards each other and about this game. I salute such leadership and hope that somehow I contribute to it in my small way.
I think of this game as a playground with lots of rides and toys and open areas to enjoy and have fun with. Like any public playground, just about every kind of person somehow wanders onto it at one time or another. Many seem to forget that the purpose is play; our kinship does not forget this from our newest to our oldest member. To me, play is actually a very serious thing and it is important to my own growth and thinking. Playing with this group of people is one of the best times, and I hope that I have been responsible and used playtime to grow and create. There are certainly times the game as it is delivered gets boring, and this must be true of all playgrounds unless we add our own creativity and expand the use of things beyond their delivered intents. There is so much more one can do with a swing than go back and forth.
Thanks, Morlocrond, for reminding me why I love this kinship and why I play with good folks like you. Now, next time you see me, let's talk some horse-talk, ok? No horse is serious, and I am a serious hobbit. Let's talk soon, kinmate.
Digger Goodsong
forever young


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As part of our Journal Club summaries our JC Chairs (Drs. Lisa Calder and Ian Stiell @EMO_Daddy) have been tasked with explaining Epidemiological concepts so that everyone in our department can analyze the literature and appraise articles on their own. For this Blog post we have all the "Epi Lesson" as they relate to "Therapy Articles". More to follow in the coming weeks.
Absolute risk reduction By: Dr. Ian Stiell November 2012
This is a very simple but important concept for interpreting the results of an intervention clinical trial. ARR tells us the difference in outcome proportion or percent between the control group and the intervention group. In the HES trial, Table 2 shows us that the primary outcome of death occurred in 18.0% of HES cases and in 17.0% of Saline cases. Hence the absolute difference was -1.0% [17.0 – 18.0 = -1.0] because HES did worse. Relative risk reduction is a little more complicated and we will do that another time.
Adjustment Analyses in Randomized Trials By Drs. Ian Stiell and Lisa Calder April 2013
Clinical trials depend upon random allocation to ensure good balance of important baseline characteristics and thus allow a fair comparison between study arms, usually by unadjusted statistical analyses. Commonly, additional secondary analyses will adjust for all important measured covariates using multivariate techniques like logistic regression. These usually confirm the findings of the primary analyses but can only be considered hypothesis generating when the secondary analyses results are different.
Adjustment of Confidence Intervals for Interim Analyses By: Dr. C Vaillancourt
Interim analyses are commonly planned in large studies. This can be useful, for example, to ensure patient safety (either by finding a significant benefit or harm early on), or as a cost saving measure by stopping the study early if there is no statistical probability to find a difference between groups later on. There are caveats to interim analyses. It is possible for a perceived "futile" study to become significant if allowed to continue on (lack of power to find a difference early on). It is also possible to find a significant difference early on by chance alone. Because the likelihood to find a difference by chance alone increases every time you analyze the data, there are strategies to account for this (such as the O'Brien Fleming Approach), most of which include raising the bar for statistical significance (i.e. p-value much smaller than 0.05 or using >95%CI instead).
Allocation concealment By: Dr. Lisa Calder December 2012
Allocation concealment is an important principle in RCT design as it helps ensure that study personnel and clinicians are unaware of how a study intervention or control is assigned. Historically, there have been instances where study personnel or clinicians have attempted to "guess" treatment allocation to ensure their patient gets assigned the "right" study group based on their own clinical biases. The robustness of an RCT is enhanced by clear reporting of how allocation was concealed, and even further if the adequacy of their concealment was evaluated.
Blinding of Treatment Allocation By: Dr. Lisa Calder January 2013
Open label trials may be promoted as pragmatic trials but a lack of blinding to treatment allocation is a fundamental threat to internal validity. Blinding reduces ascertainment bias (the likelihood of differential assessment of outcome). It is not always possible to undertake blinding in a RCT, especially for surgical or procedural interventions. Drug studies can and must be blinded so readers should be very skeptical when this has not been done. For other studies, ask yourself if it was possible to blind and whether determination of outcome was free of bias.
Clinical Diversity, Methodological Diversity and Statistical Heterogeneity
A meta-analysis may attempt to address a compelling clinical dilemma. But one of the key questions to ask when appraising meta-analyses is whether the pooling of the included studies is appropriate. Clinical diversity (or clinical heterogeneity) reflects differences between study populations, the intervention, co-interventions and/or outcomes when pooling studies in meta-analysis. Methodological diversity (or methodological heterogeneity) is variability in the study designs used and/or risks of biases present. These are distinct from statistical heterogeneity which assesses the variability in the intervention effects being assessed in the included studies. This is a consequence of clinical and/or methodological diversity. Statistical heterogeneity can be determined by: visually assessing the forest plot, measuring the I2 statistic or the Cochran's Q. A meta-analysis should be done only when the studies are relatively homogeneous for participants, interventions and outcomes to provide a meaningful summary. Always ask yourself if the meta-analysis is combining apples with apples (good) or creating a fruit salad (bad).
Clinically Important Outcomes By: Dr. Ian Stiell
Outcomes may include survival, clinical events (e.g. strokes or myocardial infarction), patient-reported outcomes (e.g. symptoms, quality of life), process outcomes (length of stay, intubation, imaging), adverse events, and economic outcomes (e.g. cost and resource use). Ideally the most important relevant outcome will be the primary outcome of the study, e.g. mortality for cardiac arrest, pain relief for analgesic studies. Be cautious of studies where processes are the primary outcome because these are of little interest to patients or their families. For example, it would be of little consolation to a family to hear that their loved one was intubated on the first pass but subsequently died.Concealment versus Blinding By: Dr. Ian Stiell March 2015
These clinical trial terms have different meanings but are often confused. Concealment refers to the process whereby the treatment allocation is made unknown or concealed prior to patient randomization. This helps prevent selection bias by ensuring that health providers and research staff are not tempted to include or exclude cases according to their views on the allocated treatment. Blinding refers to the methods employed after randomization to ensure that patients, health care providers, and research staff cannot determine whether the patient is receiving the study or the control treatment. This reduces ascertainment bias (the likelihood of differential assessment of outcome).
Contamination in Randomized Trials By: Dr. Ian Stiell May 2014
This is a type of bias where there is a mixing of treatments between study groups such that the impact of the intervention is difficult to determine. This is most likely to occur in non-drug trials where the intervention cannot be blinded and relies upon physician involvement, e.g. choosing a treatment protocol. One increasingly popular solution to this problem is to randomize by 'cluster' e.g. by hospital site, rather by patient.
Cluster Randomized Controlled Trials By Dr. Ian Stiell May 2012
A cluster randomized trial is a trial in which individuals are randomized in groups (i.e. the group is randomized, not the individual); for example, all patients treated by a particular EMS service or at a particular hospital. Reasons for performing cluster randomized trials vary. Sometimes the intervention can only be administered to the group, for example an addition to the water supply; sometimes the motivation is to avoid contamination amongst health care providers; sometimes the design is simply more convenient or economical. Such trials are often appropriate when the intervention is a psychomotor task (e.g. CPR) but not when the intervention is a drug. Specific sample size and data analytic approaches are required.
Determining Safety of a Therapeutic Agent By Dr. Lisa Calder May 2013
Many therapeutic interventions can have rare but important and sometimes fatal adverse effects. The only way to determine the safety of interventions in this case is to conduct large population studies, often via administrative databases (hence phase 4 of clinical trials designed to evaluate drugs). The critical reader will be wary of small RCTs who purport to have demonstrated safety as an outcome.
Equivalence or Non-Inferiority Trials By Dr. Ian Stiell May 2012
Most RCTs aim to determine whether one intervention is superior to another (superiority trials). Often a non-significant test of superiority is wrongly interpreted as proof of no difference between the two treatments. By contrast, equivalence trials aim to determine whether one (typically new) intervention is therapeutically similar to another (usually existing) treatment. A non-inferiority trial seeks to determine whether a new treatment is no worse than a reference treatment. Because proof of exact equality is impossible, a pre-stated margin of non-inferiority (delta) for the treatment effect in a primary patient outcome must be defined a priori. Equivalence trials are very similar, except that equivalence is defined as being within pre-stated a two-sided treatment effect. True (2-sided) equivalence therapeutic trials are rare.
Trials of healthcare interventions are often described as either explanatory or pragmatic. Explanatory trials generally measure efficacy - the benefit a treatment produces under ideal conditions, often using carefully defined subjects in a research clinic. Pragmatic trials measure effectiveness - the benefit the treatment produces in routine clinical practice. Pragmatic trials generally reflect the reality of how the intervention will perform in everyday care. For more, see http://www.bmj.com/content/316/7127/285.full
Flow Diagram By Dr. Ian Stiell December 2011
Investigators and editors developed the CONSORT Statement (revised 2010 http://www.consort-statement.org/home/) to improve the reporting of randomized controlled trials (RCTs) by means of a checklist and flow diagram. The flow diagram is intended to depict the passage of participants through an RCT and depicts numbers and explanations from four stages of a trial (enrollment, intervention allocation, follow-up, and analysis). The diagram explicitly shows the number of participants, for each intervention group, included in the primary data analysis.
Geometric Mean By: Christian Vaillancourt
A geometric mean is a type of mean or average which can be useful when combining items measured on a different scale. It is obtained by calculating the square root of the product of 2 numbers rather than dividing their sum. If we take the example of a survey where one answer is "3" on a 5-point Likert scale and another answer is "7" on a 10-point Likert scale, the usual/arithmetic "mean answer" would be (3+7)/2=5 whereas the geometric mean would be √(3x7)=4.6…which is slightly less influenced by the magnitude of the answer measured on a 10-point Likert scale.
The hazard ratio is akin to relative risk but is used for survival analyses such as Cox proportional hazards regression. It is most often used to describe the outcome of therapeutic trials where the question is, to what extent can treatment shorten the duration of an illness. The hazard ratio is an estimate of the ratio of the hazard rate in the treated versus the control group. For example if there are two groups, group 1 and group 2, HR = 4.5 for treatment means that the risk (of relapse) for group 2 is 4.5 times that of group 1.
Intention-to-treat (ITT) Analyses By: Drs. Ian Stiell & Lisa Calder January 2015
Intention-to-treat (ITT) analyses are widely recommended as the preferred approach to the analysis of most clinical trials. The basic intention-to-treat principle is that participants in trials should be analysed in the groups to which they were randomized, regardless of whether they received or adhered to the allocated intervention. This particularly becomes a problem when patients are lost to follow-up and no outcome values are available. Authors must clearly indicate how many patients have such values missing. The alternate approach is a per protocol analysis which only includes patients for whom the protocol was followed.
Interim Analyses and Stopping Rules By: Dr. Ian Stiell
In clinical trials, an interim analysis is one that is conducted before data collection has been completed to determine if there are safety issues or if the study should be stopped early. These interim analyses are evaluated by an independent Data Safety Monitoring Board that is at arm's length from the investigators. The DSMB has the authority to recommend early termination if the study intervention is clearly better than control (for benefit) or if there is so little difference between groups that full enrolment will not show a difference (for futility). Statistical stopping rules should be used to adjust the interim P-values to a much severe level, e.g. <0.001 instead of <0.05 using methods described by Pocock and O'Brien & Fleming, among others.
Describing the Strength of Study Results Using "Levels of Evidence"
By: Dr. Christian Vaillancourt
By: Dr. Christian Vaillancourt
Different methods of classifying levels of evidence have been proposed, most of them relying on the study design, their precision, or their endpoints (e.g. survival with good neurological outcome). The Oxford classification is one commonly quoted where, for e.g., Level 1a is a meta-analyses of RCTs; Level 1b is an individual high-quality RCT; Level 2 includes cohort and low-quality RCTs; Level 3 incudes case-control studies; Level 4 includes case series and low-quality cohort or case-control studies; and Level 5 is expert opinion.
Loss to Follow-up By: Dr. Lisa Calder December 2012 Evaluating loss to follow-up is a helpful tool when assessing RCT validity as it provides the reader with a sense of the integrity of the estimated difference in primary outcome. As a general rule of thumb, any loss to follow-up greater than 20% should lead the reader to become concerned about resulting bias of the main result. The reader should ask themselves: if all the patients who were lost to follow-up had the worst possible outcome, to what degree would this influence the statistical and clinical significance of the main result?
Minimal Clinically Important Difference in Clinical Trials Dr. Ian Stiell September 2014
The sample size of a clinical trial must be adequately powered to show a minimal clinically important difference (MCID) between the intervention and control arms. MCID is the absolute difference in outcome proportions that would have to be shown by the study intervention for clinicians to accept the new treatment as better. In an effort to keep sample size low, investigators sometimes estimate an MCID much larger than is reasonable or use an outcome that is not the most important, e.g. 4-hour survival rather than survival to discharge.
Minimization By: Dr. Christian Vaillancourt
The purpose of randomization is to minimize imbalance between groups. Sometimes, we know certain factors are likely to influence outcomes and ought to be equally distributed (e.g. male, female). A strategy to ensure this stratifies participants according to important factors, then uses separate randomization lists for each sub-groups. This becomes impractical when a large number of factors need to be taken into account. Minimization calculates the imbalance between groups that would result from a particular assignment, and uses a strategy favoring assignment to the group that would minimize this imbalance between comparison groups.
Modified Intention-to-treat (M-ITT) Analyses
Intention-to-treat (ITT) analyses are widely recommended as the preferred approach to the analysis of most clinical trials. The basic intention-to-treat principle is that participants in trials should be analysed in the groups to which they were randomized, regardless of whether they received or adhered to the allocated intervention, crossed over to other treatments, or were withdrawn from the study. Post-randomization exclusions may be acceptable when patients are inappropriately randomized into a clinical trial or when pre-randomization information on patients' eligibility status is not available at the time of randomization. Such an approach is known as "modified intention-to-treat" analysis and must be pre-specified in the protocol. M-ITT is most likely to be seen in RCTs of critical situations, e.g. cardiac arrest.
Dr. Venkatesh Thiruganasambandamoorthy
Multiple Arm Clinical Trials By Dr. Ian Stiell April 2013
Multiple-arm randomized trials can be more complex in their design, data analysis, and result reporting than two-arm trials. In an RCT with three arms, there are seven theoretically possible comparisons so it is important that the investigators define a priori which comparisons are of primary interest and whether they will assess global differences between all arms and/or will assess pair-wise differences of 2 arms at a time.
Multiple Comparisons and Statistical Significance By: Dr. Christian Vaillancourt
It is not uncommon for a manuscript to report several secondary outcomes. The number of secondary comparisons is directly proportional to the chance that one of them will end-up being statistically significant by chance alone. To account for this, statisticians should make it proportionally more difficult to find such a statistical difference. The Bonferroni correction suggests that the level of significance (alpha error, 0.05) should be divided by the number of comparisons made i.e. 0.05/5 comparisons = new alpha of 0.01.Phases of a clinical trial By: Dr. Ian Stiell November 2012
Non-inferiority Trials By: Dr. Lisa Calder January 2013
Non-inferiority trials are distinct from superiority trials such that they are designed to determine whether a given intervention is non-inferior by a pre-specified margin compared to a control. This is not the same as equivalence and a key section of the methods to examine is the sample size calculation where the non-inferiority margin is specified. Ideally, researchers explain how this margin was determined (based on previous placebo controlled trials, consensus of experts). The critical reader will ask themselves if they feel this margin is truly clinically significant.
Non-inferiority Trials By: Dr. Lisa Calder January 2013
Non-inferiority trials are distinct from superiority trials such that they are designed to determine whether a given intervention is non-inferior by a pre-specified margin compared to a control. This is not the same as equivalence and a key section of the methods to examine is the sample size calculation where the non-inferiority margin is specified. Ideally, researchers explain how this margin was determined (based on previous placebo controlled trials, consensus of experts). The critical reader will ask themselves if they feel this margin is truly clinically significant.
Number Needed to Treat (NNT) By: Dr. Ian Stiell May 2015
The NNT concept was created by Canadian Clinical Epidemiologist Dr Andreas Laupacis in 1988 to quantify the benefit of a new intervention. NNT is the average number of patients who need to be treated to prevent one additional bad outcome (e.g. the number of patients that need to be treated for one to benefit compared with a control in a clinical trial). It is easily calculated as the inverse of the absolute risk reduction (1/ARR). The higher the NNT the less effective the treatment.
An Assessment of Clinically Useful Measures of the Consequences of Treatment
An Assessment of Clinically Useful Measures of the Consequences of Treatment
Clinical trials involving new drugs are classified into four phases with Health Canada and the FDA generally requiring a drug to have passed through Phase 3 before general approval. Phase 1 trials test the treatment in a small group of healthy people (20-80) to evaluate its safety, dosage range, and side effects. Phase 2 trials give the treatment to patients and in larger numbers (100-300) to evaluate effectiveness and safety. Phase 3 trials give the treatment to large groups of paitents (1,000-3,000) to confirm its effectiveness, monitor side effects, and compare to commonly used treatments. Phase 4 trials are post-marketing studies to determine additional information about side effects and risks. [2a trials studies focus on proving the hypothesized mechanism of action while the larger 2b trials seek to determine the optimum dose]
Post-Randomization Exclusions By: Dr. Ian Stiell May 2014
It is widely accepted that the primary analysis of data in a randomized clinical trial should compare patients according to the group to which they were randomly allocated, regardless of patients' compliance, crossover to other treatments, or withdrawal from the study. Such an analysis is referred to as an intention to treat or an "as randomized" analysis. Exclusions, however, may be acceptable when patients are inappropriately randomized into a clinical trial or when pre-randomization information on patients' eligibility status is not available at the time of randomization. Such an approach is known as "modified intention-to-treat" analysis and is most likely to be seen in RCTs of critical situations, e.g. cardiac arrest.
Pre-specified and Post-hoc Subgroup Analyses By: Dr. Ian Stiell May 2014
Pre-specified and Post-hoc Subgroup Analyses By: Dr. Ian Stiell May 2014
Subgroup analyses involve splitting all the participant data into smaller subsets of subjects (e.g. males and females), so as to make comparisons between them. A pre-specified subgroup analysis is one that is planned and documented before any examination of the data, preferably in the study protocol. Post-hoc analyses are those planned only after examination of the results. Such analyses are of particular concern because it is often unclear how many were undertaken and whether some were motivated by inspection of the data (data-dredging). However, both pre-specified and post-hoc subgroup analyses are subject to inflated false positive rates arising from multiple testing. Subgroup analyses are often under-powered and are best used to generate new hypotheses that can be tested in future trials.
Precision in RCTs By Dr. Lisa Calder October 2012
When assessing precision of estimates for RCTs, 95% confidence intervals are most helpful. Precision can be considered the range in which the best estimates of a true value approximate the true value. Interquartile ranges for medians tell you the spread of the data for the sample used for the study, but does not give you an estimate of the probability that the true estimate falls within the range obtained.
Propensity Score Matching By: Dr. Ian Stiell September 2012
In the statistical analysis of observational data, propensity score matching is one of a family of multivariate statistical techniques that attempts to estimate the effect of a treatment, policy, or other intervention by accounting for the covariates that predict receiving the treatment. Compared to the gold standard of a randomized controlled trial, any observational analysis and interpretation of the usefulness of an intervention must be viewed with a large degree of healthy skepticism.
Random sampling vs Randomization By Dr. Lisa Calder June 2015
While in epidemiology we frequently use the word "random", there is sometimes confusion about its application. When a clinical population is randomly sampled, the goal is to ensure a representative sample. If you pre-select a sample of patients using inclusion and exclusion criteria and randomize these to a given intervention and control, you do not necessarily have a representative sample. Selection bias can still occur pre-randomization.
Randomization by Pocock minimization algorithm February 2017
A random allocation of patients to treatment-control group (by sealed envelopes etc.) generally leads to balanced groups but can lead to differences in the groups on some aspects (more males or obese patients in one arm than the other). If important factors of identified (e.g. sex, obesity) then the patients could be stratified based on sex and BMI. Using block randomization a list is created for a block of x patients to be equally assigned to the study arms based on the important factors identified. If there a large number of important factors, then the block randomization becomes extremely complex. Pocock and Simon adaptive stratified sampling algorithm can be used to calculate the imbalance between the groups based on each factor and add an additional random element to assignment of the next patient.By: Dr. Venkatesh Thiruganasambandamoorthy
When reviewing a randomized trial, it is critical to determine how the randomization was conducted as not all randomization schemes are created equal. Proper randomization uses either computer generated randomization or random tables. Pseudo-randomization includes studies where patients are allocated based on alternating days of the week or date of birth for example. The reader can verify that randomization was conducted appropriately by examining table 1 of participant characteristics and determine whether the groups appear to be balanced.
RCT Sample Size Calculation By Dr. Lisa Calder October 2012
When calculating a sample size for a randomized controlled trial, a key step is to determine the MCID: minimally clinically important difference. By powering your trial towards this difference, not only will you seek a statistically significant difference in effect but also a clinically significant one. It is important as a critical appraiser to evaluate whether you agree that the MCID is truly clinically significant.
Sample Size in Clinical Trials By Dr. Ian Stiell June 2013
Sample Size in Clinical Trials By Dr. Ian Stiell June 2013
All intervention studies should indicate how the sample size was estimated including the desired alpha error (usually 0.05), power (usually 80-90%), and expected outcome rate in the control group. Most important is a statement of the minimal clinically important difference (MCID) that would have to be shown by the study intervention for clinicians to accept the new treatment as better. In an effort to keep sample size low, investigators sometimes estimate an MCID much larger than is reasonable
Selection Bias and Randomization By Dr. Lisa Calder April 2012
Even though a clinical trial is randomized, this does not mean it cannot be subject to selection bias. Always look at the study flow figure (generally figure 1) to determine how many eligible patients were not included then assess whether the authors reasonably explain why these eligible but excluded patients were not systematically different from those who were randomized.
Stratification of Randomization by Timing of Enrolment By: Lisa Calder April 2014
Block randomization offers the benefit of ensuring overall balance of groups when you have multiple centers or clinically defined subgroups. Another approach is to randomize by the timing of enrolment when this could influence the outcome. In this study, the authors stratified their enrolment to account for early and later enrolments given that sepsis is a time sensitive condition. The sensitivity analysis for these strata reassure the reader that the overall observed effect was not influenced by timing of enrolment.
Survival Analyses By Dr. Ian Stiell February 2013
Survival analyses are used in clinical trials that follow patients over time for primary outcomes such as death, relapse, adverse drug reaction, or development of a new disease. The follow-up time may range from hours to years and a different set of statistical procedures are employed to analyze the data. Terms frequently seen in papers with survival analyses include Cox proportional hazard model, hazard ratio, Kaplan-Meir curve.
Surrogate endpoints By Dr. Venkatesh Thiruganasambandamoorthy
Can be used as a measure of effect for specific treatments and might correlate with clinical outcomes. In the RE-VERSE AD (idarucizumab for dabigatran reversal) study the investigators used dilute thrombin time and ecarin clotting time as surrogate end points for reversal of dabigatran action by the study drug idarucizumab. The actual clinical end point of restoration of hemostasis was a secondary outcome. This was a small study. We need a large clinical study with a control group to confirm that clinical outcomes among patients treated with the reversal agent were better. Be wary of studies using surrogate outcomes when clinical outcomes could have been used.
Use of Continuous Data as Primary Outcome By Dr. Ian Stiell June 2013
Beware of studies that compare the effectiveness of interventions by using continuous data outcomes, such as pain scales (1-100), oxygen saturation values, and minutes to pain relief. These kinds of data can produce statistically significant differences between groups with relatively small sample sizes but often give you little information about clinical importance. Far better and almost always the norm are outcome measures given as proportions or percentages, such as % of patients who achieve: 20 points improvement in pain, an oxygen saturation of 90%, pain relief in less than 2 hours, or survival.
Beware of studies that compare the effectiveness of interventions by using continuous data outcomes, such as pain scales (1-100), oxygen saturation values, and minutes to pain relief. These kinds of data can produce statistically significant differences between groups with relatively small sample sizes but often give you little information about clinical importance. Far better and almost always the norm are outcome measures given as proportions or percentages, such as % of patients who achieve: 20 points improvement in pain, an oxygen saturation of 90%, pain relief in less than 2 hours, or survival.
Validation of Measurement Tools By: Dr. Lisa Calder June 2014
When investigators state they used a validated tool, this means that the tool has been evaluated to determine whether it accurately measures what it aims to measure. Two important components of validity include face validity (experts endorse that the tool is logically designed to measure a given construct) and content validity (the tool comprehensively includes all possible dimensions of a given construct). These are distinct from reliability which indicates that the tool consistently measures a given construct (usually by more than one user e.g. inter-rater reliability)


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Saturday, February 14, 2009
a V happy day
and today was no different. it was made very special by Ryan, as always.
not wanting to get stuck in traffic as tomorrow is a work day, we had lunch reservations instead at Il Rustico Restaurant in Rydges Plaza Hotel. it was my pick, and i chose it because i promised Ryan long, long time ago that i will bring him there one day so he can taste their delectable pizza and pasta. Il Rustico was once a glorious restaurant praised for its authentic Italian servings. but Time Out Magazine has been harsh on them since 2007. despite the poor reviews, we still gave them a chance. i know they deserve so because i've been there last November when i underwent training, and my dining experience was great.
i didn't expect that the husband would still bother to get me flowers, but he did. on the way to the resto, we passed by Oleander, our trusted florist, and he picked up the flowers he ordered for me. i just stayed in the car and waited for my surprise. normally, he would have them delivered to my office, but today being a weekend, he opted to pick them up himself and hand them over to me. the bouquet was so lovely i was grinning from ear to ear :D
afterwards, we went straight to the restaurant to have lunch. our reservation was at half past twelve, but since we came early (12 noon), we were the first customers for the day. we had the resto to ourselves for a good half an hour before people started coming in. we were supposed to try their salads, but stopped ourselves when we were served warm bread and their famous baked garlic for appetizer. i ordered Baby Penne pasta with grilled prawns served in olive oil based cream sauce, while the hubby went for the pasta special of the day - Spinach Pasta with asparagus, smoked salmon and cherry tomatoes. it was my first choice but since i'm pregnant, i decided to go for a safer option. we also ordered Capricciosa pizza which we didn't finish because we're stuffed silly, so we took the leftovers home for merienda. for dessert, hubby had Tiramisu, which i wasn't able to taste, too because it had coffee liquor on it. i told him he has to take me back there after i give birth!
the food we chose didn't disappoint - they were delectable up to the last bite. i don't know why they were given bad reviews by the magazine. i suppose it's because compared to other Italian Restos in town, theirs is perhaps the most affordable you could find. our bill was the same as eating at any family resto here, but food, service and ambiance was way better. it's sad that people here measure the restaurant by its bill, not by its taste.
my happy Vday didn't end there. being the preggy that i am, i tend to doze off in the afternoon during weekends. when i woke up, this greeted me in the hallway:
i cannot thank the husband enough! he knows i've been wanting to get a bigger LCD TV for the longest time, and now it has finally come true! last Christmas, i didn't ask for a gift from him because he already gave me an expensive ring on our anniversary. i wasn't expecting a present such as this on Vday. i feel so loved!!
hon, you've outdone yourself yet again. thank you so much for making this day special for me! i love you to the moon and back!
happy valentine's day everyone! spread the LOVE! :)
10 comments:
- gracious said...
Happy Valentine's day Gracie.
That's a great surprise. Lovely flowers, too. :)
I super luv UP Fair. I think I went every year in my 4 years in UP. Taga dorm kasi, so super convenient. My hubby and I went to UP Fair for our first Valentine date. :)
Take care.
- February 15, 2009 at 12:15 AM
- Jacqui Co-Soriano said...
hey gracie, UP Iska ka din pala... hehehe! Like you, I look forward to UP Fair din...my ex-bf(s) kasi both fratman, kaya may mga harana nights sila pag Valentine's day. Wala lang, nakaka-aliw to reminisce! hehehe!
Btw, love the samsung LCD. kami we had it wall-mounted, libre pa wall-mount dito sa manila! Dyan ba libre din? Anyway, enjoy your big tv! (ay naku, si husband lagi nanonood dyan, PBA! hehehe!)
Belated Happy v-day!
- February 15, 2009 at 5:54 PM
- Gracie said...
hi gracious,
that's sweet! memorable din pala sa inyo ni hubby ang Feb Fair :) i don't know but there's something really special about Feb Fairs, no? simple lang but it's so magical *mushy*
happy vday, too! sure yours went great.
- February 15, 2009 at 7:20 PM
- Gracie said...
hi jacqui,
yep, certified isko't iska kami ni hubby :) madami talagang memories ang Feb Fair...sarap din balik-balikan :D
love my new TV! very happy with its size. he almost picked the 52" too much na! free din wall mount dito. did i tell you the TV came with a free 32" LCD? cool no? :)
- February 15, 2009 at 7:23 PM
- Mich said...
awww, love the flowers gracie! :)
belated happy vday!
- February 16, 2009 at 12:36 PM
- Jacqui Co-Soriano said...
Ah talaga kayo ni husband UP. Let me guess, econ kayo noh?! hehehe! Ako naman Home Eka-nanay, HRA grad ako. Ay naku nasa news ngayon yun gulo sa UP Fair last Friday. Nagka-gulo sa free concert. Tsk..tsk...
Anyway, really may free LCD TV dyan?! Wala dito yan ah, promo dito ka-bundle na home theater. Tipong you add P5K (or P15K), may home theater system na. Package na 6-speaker surround system, dvd/vcd player. Yun ang na-avail namin. We got the 42" naman. Sakto for living room. Laki siguro ng 52" mo?! Hahaha! Pero really nice Samsung brand. Good buy!
- February 16, 2009 at 3:56 PM
- Gracie said...
hi jacqui,
dito ang promo nila series 6 na 46" with free 22". pero yung sa min, series 5 46" then 32" ang free. good buy talaga! :)
naku, hindi ako econ (though 1st choice ko yun!). comm arts ako...si hubby applied math - both grads of UPLB.
- February 16, 2009 at 7:08 PM
- Gracie said...
hi mich,
thanks! will be posting more of the macro shots in the next coming days :)belated happy vday!
- February 16, 2009 at 7:11 PM
- Joanne MV said...
Wow! Lucky you sis! :)
- February 18, 2009 at 6:56 AM
- Gracie said...
hi joanne,
thanks sis! i'm just milking my preggy days kse spoiled nang sobra sa hubby! :)
- February 18, 2009 at 8:59 PM


text:
Barre Classic is perfect for a beginner through to intermediate. Using isometric movements combined with the power of music to increase strength, flexibility, stamina and dynamic stability. It is a class geared for everyone—no ballet experience required!
Barre cardio is a great way to increase your heart rate, improve your fitness, build strength and tone. It is fun, beginner friendly class that will improve energy, fitness and help with weight loss.
Barre stretch is an amazing class for the mind and body. Holding each stretch for 2-4mins, this helps lengthen and releases any tightness in your sore muscles. Ending the class is an guided meditation, perfect after a long day. We do suggest completing the stretch class after a barre classic class to ensure your muscles are nice and warm . If you are only attending stretch we recommend a 10 min walk/jog prior to walking in.
Barre Hitt combines elements of High-Intensity Interval Training (HIIT), Circuit Training, and Barre. This combination of interval, cardiovascular and strength training is an effective workout method for burning fat and building lean muscle.
Barre Ballet provides a basic foundation of ballet technique, core strength and flexibility. Previous ballet experience isn't necessary. No ballet shoes required. 45 mins.
Mat Pilates is a system of controlled exercises that engage the mind and condition the total body. The blend of strength and flexibility training improves posture, reduces stress and creates long, lean muscles without bulking up. Pilates takes a balanced approach so that no muscle group is overworked and the body moves as an efficient, holistic system in sport and daily activity. 45 mins.
Enjoy a great work out whilst bonding with your baby. Yummy Mummies are most welcome to attend our 7am Mat Pilates Class and 9:15am Barre Classic Classes (Monday – Friday). Restore that strength and regain your posture. A baby carrier is required for class. We do have some for hire $5 however we only have limited numbers. NOTE: New Mums must be at least 12 weeks post pregnancy. If new mums have any abdominal separation and pelvic issues you will require a letter from you doctor as barre may not be suitable whilst healing.
Barre Flow is inspired from vinyasa yoga, each movement is synchronised to a breath. Expect to move, sometimes vigorously, from pose to pose. Whether the class is fast or slow, it will include yoga poses as well as flowing barre exercises. Classes include some warm-up stretches at the beginning then straight into flow. This class is low impact and great for overall core strength and clearing the mind.
Build a weekly team ritual with private classes in our super chic studio. Another option is we can bring BARRE to your workplace. Tailored to your class style preference and price. For classes at your office, we can provide barres and any other equipment needed.
More info email: email@example.com


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11 Caledonia Ave Kingston 5 JamaicaGet directions
KingAlarm Systems began operations in March 2000 and, in a relatively short time, has become the largest Electronic Security Company not just in Jamaica but the entire Caribbe
an, serving in excess of 8,000 satisfied customers.
KingAlarm specialises in the installation and servicing of Electronic Security Systems for both Residential and Commercial applications.
We operate our own 24 Hour Central Monitoring Centre, and utilise our own highly trained Armed Response Teams, in providing Monitoring and Armed Response Services to priority alarm signals from our client locations.
Our state-of-the-art Monitoring Centre is manned round the clock by at least five (5) specialist Central Station Operators, and same is equipped with fully redundant systems to ensure uninterrupted service in the event of emergencies, loss of power or equipment failure.
KingAlarm has consistently maintained the very best Response Team: Client ratio in the Industry, therefore ensuring the b est possible response times to all emergencies, and making our service second to none.
All KingAlarm monitored clients benefit from the FREE Ambulance Response Service at their primary locations, along with free Roadside Assistance, Escort and Party Patrol services all of which were conceptualized by us and introduced to the market at the time of our inception.
KingAlarm offers complete system design and reliable after sales service, along with FREE Risk Assessments, Security Audits and Surveys.
Aside from offering state-of-the-art equipment backed by the excellent Customer Service, we at KingAlarm ensure that our products and services are cost effectively priced to suit your pocket.
As such, we have been credited for making high quality Electronic Security Systems not just a luxury for the chosen few, but available, and affordable, to more and more persons across the Jamaican landscape. Read more......Read less
27A Barbados Ave Kingston 5 JamaicaGet directions
Security & Professionalism are our trademarks.
S.A.M.S was established in March 1987 by three former army officers with the aim of offering a professional, comprehensiv e security management service. The simple fact of the matter was that the principle of a man, with a gun and a dog, being security was not absolute.
The company was founded on the premise that security must be appropriately treated as a management function which, like all other aspects of management, directly affects the long-term financial viability of every business.
S.A.M.S is adept at solving security problems, and since we do not work off a template, but rather treat each client as if they were our only client, we have to be flexible.
We are a solutions driven company, and we wholeheartedly believe that all security problems that are presented to us can, and will be solved.
Suffice it to say, our reputation has grown to the extent that our very presence in a company can, and freq uently does, act as a deterrent to potential wrongdoers.
Much of what we do has to do with a change in psychology. Through the simple act of S.A.M.S assuming the responsibility to deal with the threat to a client, the client frequently experiences a sense of security improvement among management and employees. As a consequence, productivity improves, losses are reduced, and there is a commensurate increase in profits. Read more......Read less
The Company, established in September 1987 by the three wharf companies in Kingston, Jamaica [Kingston Wharves Limited (KWL), Western Terminals Limited (WTL) and Kingston Term
inal Operators Limited (KTO)] became a 100% subsidiary of KWL when that company completed the acquisition of the shareholdings of the other wharf companies in 2000. A new partnership developed in 2002 and SAL is now jointly owned by KWL and the Port Authority of Jamaica (PAJ).
Security Administrators Limited is the security provider at Kingston Wharves and Port Bustamante, and provides Specialist Anti-Narcotic Security on vessels in Kingston and Montego Bay. The Company has been the leading provider of maritime security and related services in Jamaica for almost two decades and our performance has resulted in a proud record of achievement that has made us an integral part of the Shipping Industry in Jamaica and the region.
The Company's outstanding performance in the area of antinarcotic security has resulted in approximately 85% of all drug finds at Port Bustamante being made by SAL personnel, an achievement that has been recognised by several clients and the United States Customs who have utilised some of our training programmes and equipment.
In 2004, SAL was appointed a Recognised Security Organisation by the Contracting Government in Jamaica (The Port Authority of Jamaica) and is authorised to conduct Port Facility Security Assessments (PFSAs) and prepare Port Facility Security Plans (PFSPs), in keeping with the requirements of the International Ship and Port Facility Security (ISPS) Code.
In 2006, SAL became the regional distributor of VideoRay Remotely Operated Vehicle (ROV) machines. A contract was signed between Security Administrators Limited (SAL) Chairman, Grantley Stephenson and VideoRay President Scott Bentley, which allows SAL to undertake sales of ROVs in the Caribbean.
In February 2008 SAL has expanded its services to offer Industrial Security Services and since has been providing industrial security guards on the port of Kingston. This decision was made because of our experience and expertise and because the customers have wished it.
We have also signed a joint agreement with the Caribbean Maritime Institute (CMI) to conduct an Advanced Port Facility Security Officers Course and a Bachelor of Science Degree in Security Administration & Management. Read more......Read less


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A Few of this Sportage's key features include: **POWER WINDOWS**, **KEYLESS ENTRY**, **STEERING WHEEL AUDIO CONTROLS**, **SATELLITE RADIO**, an **AUXILIARY AUDIO INPUT**, **ELECTRIC STABILITY CONTROL**, **ALL WHEEL DRIVE**, All Wheel Drive, Keyless Entry, **ALUMINUM WHEELS, Electronic Stability Control, Steering Wheel Audio Controls, Power Windows, Satellite Radio, an Auxiliary Audio Input, and Aluminum Wheels.
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Call Letter
Deans, Vice Chancellors, Chief Administrative Officers, and Divisional Finance Leaders received their FY2017-18 budget call letters. As a complement to recent budget discussions with the EVCP and CFO, this letter provides campus leaders with additional critical information needed to complete their divisional budget for formal submission, along with their division's strategic plans and revenue generation plans, by early May.
Campus Guidelines
The FY2017-18 campus guidelines, updated annually by the Office of the CFO Financial Planning & Analysis Team, provide guidance to divisions including key dates, planning assumptions, and links to helpful tools and resources.


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This key, wich is shaped like a pyramid, is the key to the secret room that contains Sendell's Ball, in the sewers of Citadel Island.
After bringing the gallic acid to Twinsen's neighbour, he uses it to restore some documents belonging to his late son. This reveals a map with instructions that mention the key, which the neighbour then gives to Twinsen.
Inventory DescriptionEdit
"This Pyramid is a key. If you put it in the right place, it will activate a mechanism giving you access to a secret place."