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Nonsensicality is a fanfiction written by Ł☨ and Foxo and edited by Foxo. Edit
chap 1 ☨ 🇫 Edit
Hi. I'm Springleaf. I have what the RiverClan medicine cat calls "Nonsensicality". I get distracted easily, I'm "more intelligent than other cats", and I honestly don't care how I sound or look. I often sporadically offend others. I don't care though. I'm me and if cats don't like it, then that's not my problem. I don't have a mate or any admirers; at least, I don't think any tom or she-cat would be stupid enough to care about the abnormality that is me.
chap 2 ☨ 🇫 Edit
I caught more menacing and threatening glares as I trotted into the RiverClan camp. Most cats here either hated me or thought I was weird, which is true. I padded up to Drippaw without realizing exactly what I was doing and let go of the extremely heavy bass I was previously holding in my jaws. It thudded to his feet, glistening brightly in the Newleaf sunshine. He looked at me like an idiot and before I knew it, I was sitting down, sharing a meal with him. I turned my head up and looked him straight in the eyes. "Why are you blushing so much, Drippaw?", I asked him straightforwardly. He looked like a slightly blue-furred tomato that looked nothing at all like a tomato (I'm trying to say he was blushing). I ignored him and finished my bass, leaving him with the remains. "Goodnight." I said shortly, flicking Drippaw teasingly with my tail as I strode back to my den.
chap 3 ☨ 🇫 Edit
I woke up from a dream of a not-so-mysterious blue-coated apprentice. I couldn't shake the feeling that there was some reason that I needed to be around him. Once again, without a proper thought process, I picked myself up from my ridiculously matted den and looked around. I spotted his shiny, slicked pelt across the camp and quickly groomed myself before prancing over to his spot. He looked up at me nervously, despite me being shorter than himself. "Y-You look stunning!" he mumbled shyly. "No I don't. I look like a poorly self-managed she cat." I said, almost robotically. I quickly adjusted my response. "Sorry. I meant to say that you look great as well." I said, in a flat but semi-real voice. Did I just... apologize?! When have I ever apologized?! I screamed in my head, realizing what I had just done. Without a second thought about the subject, I plopped down close to Drippaw. More closely than I had intended, but also strangely comfortable... I sniffled and turned to his face. "When are they planning to make you a warrior?" I asked, much too friendly and sweetly for my normal tone. He purred, a deep, rattling sound. Before i had known it, I was purring along with him, my eyes closed. Who is this tom and why is he making me act this way?
chap 4 ☨ 🇫 Edit
I woke up practically draped over Springleaf's slender figure. Immediately, confusing thoughts rushed into my head. When did we fall asleep? Why didn't she leave? Does she like me? ...Why is she so cute? Why did she talk to me? I thought she hated me... My thoughts were cut short as Springleaf roused from her sleep, lifting her slim head off my shoulder and blinking slowly. Her gaze met mine and she did something that I didn't expect. She blushed. I instantly blushed along with her, not breaking our gaze. Suddenly, she stood up. "I must go hunting. I know it's late, perhaps you'd like to come with me?" My heart nearly stopped at the thought of the slightly older warrior's offer. I nodded furiously in response, and I joined her in standing. After a quick grooming, we were off into the darkness of night.
chap 5 ☨ 🇫 Edit
drippaw was here again. the dark place. he wandered around once more, confused. he glanced to his right side as a white and black figure approached him. he recoiled in pure disgust as he realized what this was. the cat was a skeleton, rotten muscles hanging off of its bones, which were clearly visible under the strands. drippaw's eyes opened wide, taking in the eyeless, peltless figure. "wh-who a-are you?" the figure made a small rattling sound as it turned its skull to face him. "I am your self loathing. I am everything you despise about yourself, all of your petty inadequacies. I am what you hate about the being that is You." drippaw took a pawstep back, gazing in horror at the piteous creature that stood in front of him. the creature grinned, a hideous and disgusting gesture of pure malice. "You and Springleaf? Never gonna happen. You're worthless. You disgust her and you know it, you freak. You wonder why they haven't made you a warrior yet? It's because you're not good enough. You'll nev-" the words faded as drippaw shook with sobs. "stop. please." he moaned, tears splattering the ground. the grin turned into a wicked smile. "Enjoy your time with your 'mistress'..." he laughed, smiling with devious content. "I'll see you soon, pet." he murmured, before disappearing into a thin cloud of fog.
chap 6 ☨ 🇫 Edit
I turned around, slightly confused as to why Drippaw was not accompanying me. I turned my head back, a playful grin on my face; it quickly faded as I saw him behind me. He was sobbing quietly, his head in between his paws as it shook with tears. I blinked with a mixture of shock and suppressed confusion, forcing myself to pad up to the emotional disaster that was Drippaw. "Are you alright?" I asked bluntly, internally scolding myself for not acting like I cared. He looked up at me, his green eyes piercing mine; I understood the magnitude of the pain he was feeling in that moment. I did not understand what was wrong, but I understood that he was in a horrible place of mind and that I needed to help him. (stopped)

subset: commoncrawl


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SleeterCon is back, bigger, bolder and broader than ever! This year's extravaganza kicks off with an eye-opening zip line experience down Fremont Street, features a Cirque du Solutions reception sponsored by Intuit where attendees get an interactive opportunity to network and win prizes, and concludes with a special guest band playing throwback music for Sleeter Group Consultants Network members to dance the night away and relive the '80s.
Each year, the Sleeter Conference's vision is to help the audience evaluate, navigate and adopt technologies that will benefit their client base, while also providing unprecedented access to the minds that change the industry. Some of those game-changers can be found in a bevy of inspiring keynote speakers, including Tom Hood, an influencer in leadership, learning and technology, and a nine-time recipient of the Top 100 Most Influential People in Accounting recognition; our very own Jim McGinnis, vice president, Intuit Accountant and Advisory Group; Amy Vetter, Global Vice President, Education & Enablement, US Head of Accounting for Xero, and accomplished author and speaker; and, of course, the man behind it all – Doug Sleeter.
SleeterCon 2015 focuses around getting firms to crush their comfort zone and capitalize on disruptive trends, The four education-packed days provide everything a business needs to embrace the disruption with confidence, and get themselves on the right track to being a Firm of the Future. Helping get you there will be more than 70 sessions, 80 exhibitors and a plethora of networking opportunities.
You won't want to miss out on this special conference, held at the Bellagio Resort and Casino in Las Vegas from November 16-19. Click here to register today. We hope to see you there!


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We live in a "noisy" culture. These days everybody has something to say and everybody has a platform to say it from. There are many wonderful things about this social media age, but there is no denying it's noisier than ever. When it's noisy it's hard to be heard and being heard is a critical component to being a successful coach.
In his book "Platform: Get Noticed in a Noisy World" Michael Hyatt (@MichaelHyatt) shares his wisdom on using social media and the internet to build a business platform. While some of his wisdom isn't applicable to the coach, much of it is. In my previous post, "3 reasons football coaches must be salesmen", post we learned why we, as coaches, are all in sales. This post we are going to discuss why we all must establish and build a platform for our programs.
What is a platform? A platform is any position of influence you use to state, defend, and build your vision for your team. It's a place where you state why your program exists, what you're all about, and establish expectations and norms.
Here are 5 keys to establishing and building your platform:
1. Know who you are…
…and act like who you are. We live in a teenage driven society. The internet age has transformed teenagers into power wielding influencers and consumers. This reality subconsciously places pressure on leaders of teenagers to be like the teenagers. As a result, there are a lot of coaches running around trying to be like teenagers. Essentially, one aspect of their platform is "I'm like you. Come join my team."
While I think part of building your platform is engaging your players where they're at I also think it's a mistake to be like your players. This means using Twitter to communicate who you are and what you're team is all about is probably good as long as you act like a professional and not a teenager while on Twitter (or any other social media network).
2. Create a "Wow experience"
This is straight out of Hyatt's book. In an age when everyone is able to cast their ideas before thousands of people you had better make sure that whatever you are casting is of extremely high quality. For the football coach this means that being a player on your team and being a parent in your program must be a "wow experience." This doesn't necessarily mean winning championships. It means focusing on developing people as well as players. Whether you go 0-10 or 10-0 you need to be in the business of developing men and providing a wow experience for everyone involved.
3. Think beyond Facebook and Twitter
This isn't a post about building a team Facebook page/group or Twitter account. This is a post about recognizing all of your potential resources and using them to build your brand. What's your brand? It's your way of conducting a football program.
I think our head coach does a great job of thinking beyond Facebook and Twitter every year at our preseason BBQ and our postseason banquet. He is always careful to explain how our team defines success, what we value, and why we value it. Both events are family events so the entire football community is in attendance. If you attend both events you know what our program is all about. Our "brand" is obvious. Our platform is clear.
4. Strive for quality over quantity
Back in college a friend and I spent two summers working for a concrete company. One day he looked over the enormous worksite we were at and asked "Whatever happened to quality?" I answered "Quantity."
Over the years I've learned it's not how much you communicate it's how well you communicate. If you choose to blog or tweet or host annual events you need to maximize every interaction and make sure each one is a well crafted communication. I've learned that a really well done end of season banquet is far more powerful than weekly emails. Both may have a rightful spot in your platform, but you need to recognize the power of quality and reject the myth that quantity is the is the key to effective communication.
5. Peel back the curtain
Your players are highly relational. Way more so than you were at their age. They want to know you. They want to know about your hobbies, your favorite foods, what you like to do with your free time, etc. As Tim Elmore (@TimElmore) would say they don't want a "sage on the stage" they want a "guide on the side." Use your platform to show your players an aspect of your life and personality they may not see at practice or on game day. This could involve posting pictures with your family, telling stories about your experiences, or just being willing to actually get choked up in front of them every once in a while.
Remember, the key to having a great platform isn't being the noisiest. The key is having something important to say. Being intentional and actually having something worthwhile to say is the topic of my next post. In the meantime, take a moment to share some ways you are already building or plan to start building your platform.


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Have you discovered Sho Ko yet? Watch these two adorable cats, Shorty and Kodi, showcase their cunning cat moves while amusing themselves in their happy home. The duo, also known as Sho Ko, are featured via YouTube and Facebook, where fans can get a chuckle while enjoying their shenanigans. Click to watch this pet video of the day featuring a compilation of hilarious Sho Ko moments.
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text: DUI Questionnaire If you do not forward this information to our office, be prepared to give this information over the phone. Arrest Information Date of arrest: Time of arrest: City and state of arrest: Exact location of arrest ( i.e. intersection of Sahara and Las Vegas Blvd ) Arresting agency: Why were you stopped? Do you have any physical limitations that would hinder your ability to take the field sobriety tests? YesNo Which field sobriety tests did you take? Please check all that apply. Horizontal Gaze NystagmusOne Leg StandWalk and TurnFinger Counting How do you feel you did on these tests? Please elaborate. Did you take a blood or breath test, or did you refuse all chemical testing? Please check all that apply. Blood TestBreath Test On SceneBreath Test Other LocationRefused All Tests Except Breath On SceneRefused All Tests What were the results of these tests? Were you advised that you had a right to refuse the breath test? YesNo Were you advised that if you refused that you would lose your license for period of time if you had priors? YesNo Were you advised that there was mandatory jail time if you refused and were convicted? YesNo Were you advised that your refusal could be used against you in court? YesNo Did the officer confuse you in any way? YesNo What county and court is your case in? When are you to appear? Have you ever been arrested for any other alcohol or drug offenses? Valid Nevada Driver's License Number Out-of-State Driver's License Number Confiscated License? YesNo Was your vehicle impounded? YesNo Did you post bail? YesNo Bail Amount Biographical Information What is your name? What is your address? List the phone numbers where you can be contacted. Can messages be left at these numbers? YesNo What is you email address? Age Sex MaleFemale Weight Occupation License necessary for employment? Please enter the characters seen below: In addition to clicking the "Submit" button above, please copy and paste this information in an e-mail to The Law Office of Garrett T. Ogata Call (702) 366-0891 for a free consultation.


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April 19, 2012
The news and information source for faculty and staff
It's not exactly the city that never sleeps. More like the city that thinks, learns, works and plays, often at all hours. Whether it's Chaucer or softball, cleaning crews or late-night studying, Babcock ice cream or crowded class-change sidewalks, UW is alive with activity. On Wednesday, Badgers all around the world (including these SAFEWalkers, pictured) participated in a wildly successful effort to document 24 hours in the life of the university.
Ahead of Sunday's Earth Day, listen to a podcast with Craig Benson, director of sustainability research and education for the new Office of Sustainability. Benson discusses how the office will encourage research of responsible uses for resources, give students the tools to consider sustainability and strengthen campus ties to the rest of the state.
UW System President Kevin P. Reilly has appointed Dean of International Studies and Vice-Provost for Globalization Gilles Bousquet as UW-Eau Claire's Interim Chancellor following the departure of Chancellor Brian Levin-Stankevich next month. Bousquet's appointment begins on July 15.
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The fourth concert in Pro Arte's centennial celebration features the premiere of String Quartet No. 5 by John Harbison; String Quartet in C major, Op. 54, No. 2 by Haydn; and String Quartet in D major by Franck. John Harbison and author/editor Tully Potter will hold a pre-concert conversation from 7-7:30 p.m. in Mills Hall.
As completion of tower two of the Wisconsin Institutes for Medical Research nears, the McArdle Laboratory for Cancer Research readies for a move that is much more than a relocation to the health sciences campus.
The Wisconsin High School Forensic Association will hold its annual Wisconsin Speech Festival on campus the afternoon of Friday, April 20, and the morning of Saturday, April 21. With nearly 5,000 students on campus, there may be some traffic congestion.
African Studies has been a vibrant part of campus since 1961. To mark 50 years of work and accomplishment, it is hosting a three-day conference and reunion, "50/Forward: A Half-Century of African Studies at Wisconsin," Friday, April 20, through Sunday, April 22, at the Pyle Center.
Kristin Phillips-Court, a professor of French and Italian, recently sat down with the College of Letters & Science to talk about her popular interdisciplinary class, "The Italian Renaissance: Authorship and World-making."
"Paint your garden" is the Allen Centennial Gardens theme for 2012. ACG director Ed Lyon explains in this CALS video.
1,085,374: That's the number of annual student credit hours taken on campus in 2010-11. And, it's one of a zillion facts available in the latest edition of the university's Data Digest, just published by the Office of Academic Planning and Analysis, available here.
Four of the most significant awards in chemistry were awarded to UW-Madison professors in a ceremony at the spring meeting of the American Chemical Society in San Diego.
Two days of events celebrating the official groundbreaking for the new School of Nursing building are planned for Saturday, April 21, and Sunday, April 22.
Take a few minutes to learn the history behind Gaylord Nelson and Earth Day. "Gaylord Nelson and Earth Day: The Making of the Modern Environmental Movement," tells the story of how Nelson's idea, conceived as a "national teach-in on the environment," became a historic turning point.
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Wholesale orders are accepted with 24 piece minimum.


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Alexander G. Crockett
|Alexander G. Crockett
|Member of the Virginia Senate
from the 5th district
|In office
January 10, 1912 – January 12, 1916
|Preceded by
|A. Pendleton Strother
|Succeeded by
|E. Lee Trinkle
|Personal details
|Alexander George Crockett
February 22, 1862
Wythe, Virginia, U.S.
|July 27, 1919
(aged 57)
Max Meadows, Virginia, U.S.
|Political party
|Mary Raper Thorne
Elizabeth Mcgavock Robertson
|Alma mater
|Emory & Henry College
Vanderbilt University
Alexander George Crockett (February 22, 1862 – July 27, 1919) was an American Democratic politician who served as a member of the Virginia Senate, representing the state's 5th district.[1]
- ^ Swem, Earl G. (1918). Register of the General Assembly of Virginia, 1776–1918. Richmond: Virginia State Library. Retrieved April 25, 2014.
External links[edit]
- Alexander G. Crockett at The Virginia Elections and State Elected Officials Database Project, 1776-2007
- Alexander G. Crockett at Find a Grave
|This article about a Virginia State Senator is a stub. You can help Wikipedia by expanding it.


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Exisulind is an apoptotic agent with preclinical activity in non-small cell lung cancer (NSCLC). Vinorelbine is safe and effective in older patients with advanced NSCLC. We assessed these agents together as palliative treatment for older patients with advanced NSCLC.
Chemotherapy-naïve patients ≥ 70 years old with stage IIIB-IV NSCLC and a performance status (PS) ≤ 2 were eligible. Primary endpoints were the maximum tolerated dose (MTD, phase I) and time-to-progression (TTP, phase II) of oral exisulind with 25 mg/m2/week of intravenous (IV) vinorelbine on a 28-day cycle. Patients with clinical benefit after six cycles of this combination received exisulind alone.
Fourteen phase I patients (median PS 1; median age 78 years) were enrolled. Dose-limiting toxicities included grade 3 constipation (one patient), grade 3 febrile neutropenia (one patient) and grade 3 diarrhea (one patient). The MTD of oral exisulind with 25 mg/m2/week of IV vinorelbine was 125 mg twice daily. Thirty phase II patients (median PS 1; median age 78 years) were enrolled. Grade ≥ 3 neutropenia occurred in 14/30 patients. Two patients experienced neutropenic fever. There were no complete responses, one partial response and 12 patients with stable disease as their best response. The objective response rate was 4.0% (95% CI: 0.1–20.4%). Phase II median TTP was 4.7 months (95% CI: 3.1 – 9.3 months) and median OS was 9.6 months (95% CI: 6.6 – 19.1 months).
This combination is safe, appears to have activity in the elderly with advanced NSCLC and a PS ≤ 2, and warrants further investigation.
Lung cancer is common after age 70. Between 2001 and 2003, it was diagnosed in 1 in 15 males and 1 in 22 females in this age cohort, compared with 1 in 38 males and 1 in 54 females aged 60 to 69 years.1 Clinical researchers are increasingly recognizing that the elderly with cancer should be studied as a distinct population.2
Vinorelbine has demonstrated efficacy in older patients with advanced NSCLC. In a phase II study, Gridelli treated patients at least 70 years old with stage IIIB-IV NSCLC with first-line vinorelbine (30 mg/m2/week).3 Median age was 73 years and median Eastern Cooperative Oncology Group (ECOG) performance status (PS)3 was 2 (22/78 patients). Median time-to-progression (TTP) was 11 weeks and median overall survival (OS) was 36 weeks. The phase III Elderly Lung Cancer Vinorelbine Study (ELVIS) randomized patients at least 70 years old with stage IIIB/IV NSCLC to best supportive care (BSC) or BSC with weekly vinorelbine.4 The median ECOG PS was 2 (19/43 patients). Patients receiving vinorelbine experienced a superior median OS (28 versus 21 weeks) and improved quality of life.
Exisulind (sulindac sulfone; OSI Pharmaceuticals, Melville, NY) is an orally available inducer of apoptosis in cancer cells via inhibition of cyclic guanosine monophosphate phosphodiesterase and activation of protein kinase G.5–7 It may also inhibit angiogenesis.9 Exisulind demonstrated preclinical activity in NSCLC.8–10 Phase I testing of exisulind in patients aged 18–45 years with familial adenomatous polyposis (FAP) and subtotal colectomy recommended a phase II dose of 300 mg orally twice daily continuously.11 Treatment was well tolerated. Predominant toxicities included reversible grade ≤ 3 hepatotoxicity, grade ≤ 2 headaches and grade ≤ 2 gastrointestinal disturbance.
Based on the preclinical activity of exisulind in NSCLC models, its favorable toxicity profile, and the non-overlapping mechanisms of action of vinorelbine and exisulind, we conducted a phase I/II trial of first-line exisulind/vinorelbine for patients with stage IIIB-IV NSCLC who were at least 70 years old and ECOG PS ≤ 2. The phase I primary objective was to find dose limiting toxicities (DLT), the maximum tolerated dose (MTD) and recommended phase II dose of this combination. The phase II primary objective was to evaluate the clinical efficacy in prolonging TTP. The secondary objectives were to evaluate toxicities, objective RR and OS.
Eligible patients were ≥ 70 years of age, chemotherapy-naive, had an ECOG PS ≤ 2, histologically-confirmed stage IIIB (pleural effusion) or IV NSCLC, measurable disease and adequate major organ function [white blood cell count ≥ 3,500/mm3, absolute neutrophil count (ANC) ≥ 1,500/mm3, platelet count ≥ 100,000/mm3, creatinine ≤ 2.0 mg/dl or creatinine clearance ≥ 60 mg/dl, total bilirubin (TB) < institutional upper limit of normal (ULN), aspartate transaminase (AST) ≤ 1.5 ULN and alkaline phosphatase (ALP) ≤ 2.5 ULN]. Prior radiotherapy was allowed if there was measurable disease outside of or progressive disease within the radiotherapy port. Exclusion criteria included clinically unstable brain metastasis, use of non-steroidal anti-inflammatory medications within two weeks (except ibuprofen, naproxen and low dose aspirin) and subtotal colectomy. The Institutional Review Board of the University of Wisconsin and participating institutions approved the study protocol. All enrolled patients provided written informed consent.
Baseline laboratory and imaging studies were performed within two and four weeks prior, respectively, of enrollment. Subsequent lab studies were performed on day 1 of each cycle. A complete blood count was drawn weekly. Measurable disease was reimaged and graded using Response Evaluation Criteria in Solid Tumors14 every two cycles.
OSI Pharmaceuticals (Melville, NY) provided exisulind as 125 mg capsules. We used pill counts to monitor exisulind compliance.
During the phase I study, exisulind (dose level 1, 125 mg twice a day; dose level 2, 125 mg in the morning and 250 mg in the evening; and dose level 3, 250 mg in the morning and 250 mg in the evening) was combined with 25 mg/m2/week (without interruption) of intravenous vinorelbine on a 4-week cycle. The MTD was used as the phase II regimen.
Progressive disease (PD), treatment intolerance, treatment delay of either drug > 14 days and withdrawn consent were reasons for ceasing treatment. Otherwise, patients received up to six cycles of vinorelbine with exisulind followed by exisulind alone (initially at the cycle 6 dose).
Granulocyte colony simulating factor (G-CSF) support was not used in the phase I study. G-CSF was used during phase II for grade 4 neutropenia > 5 days and recurrent neutropenia, followed by prophylactic G-CSF in subsequent cycles.
Toxicities were graded according to the National Cancer Institute Common Toxicity Criteria, version 2.0. DLT was defined as grade 4 neutropenia ≥ 7 days, grade 4 neutropenia and fever (any oral temperature > 38.5°C, or three elevations > 38°C/24 hours) requiring parenteral antibiotics, grade 4 thrombocytopenia, delay in treatment > 14 days and other non-hematological grade ≥ 3 toxicity.
The MTD was determined during cycle 1 using a traditional 3-by-3 cohort design as previously described.12
The primary endpoint of the phase I study was toxicity. The primary endpoint of the phase II study was TTP. Secondary endpoints included safety, tolerability, objective RR and OS.
The sample size estimate for phase II enrollment did not include phase I patients. Utilizing standard approximations based upon an exponential distribution for time to event assuming that patient accrual is uniform over time, we estimated that 27 disease progressions would need to be observed. This sample size would provide 90% power to detect a 50% increase in median TTP from 11 weeks for historical control13 to 16.5 weeks on the protocol therapy according to a one-sided logrank test at the 0.2 signifiance level. Our rationale was that we were not so much concerned about falsely claiming efficacy of this therapy, but rather we did not want to overlook a promising therapy because of limited power. We planned to accrue 30 patients with an additional follow up after the last patient was enrolled until there were 27 disease progressions.
According to this design, this combination would be considered for further testing if the observed median TTP was > 13 weeks, corresponding to the 80% lower confidence limit for the true median TTP with the protocol therapy when 27 disease progressions were observed in the study. TTP and OS were defined as the time elapsed between study enrollment and progressive disease (PD) and death, respectively. Patients completing two cycles of treatment were evaluable for objective response. All enrolled patients were considered evaluable for OS and TTP (intent-to-treat). TTP and OS were analyzed using the Kaplan-Meier method.14 Quantitative and qualitative toxicities, as well as objective RR were summarized with descriptive statistics.
Fourteen patients enrolled in the phase I study between April 2001 and June 2002 (Table 1). Thirty patients enrolled in the phase II study between November 2002 and May 2004 (Table 1).
After no DLTs were observed in three patients at dose level 1 (125 mg of exisulind twice a day), four patients enrolled at dose level 2 (125 mg of exisulind in the morning and 250 mg in the evening). Two dose level 2 patients experienced a DLT (grade 3 constipation and grade 3 diarrhea). Dose level 2 was expanded by five patients. Two were replaced because of death during cycle 1 unrelated to treatment (one patient) and withdrawn consent (one patient). One patient in this expanded cohort experienced a DLT (grade 4 neutropenic fever). Therefore, the MTD was designated as 125 mg exisulind twice a day orally continuously with 25 mg/m2/week intravenous vinorelbine on a 4-week cycle.
Fourteen phase I patients received a median 2 cycles of vinorelbine with exisulind (41 cycles total; range, 0.5 to 6 cycles) and a median zero cycles of exisulind alone (60.0 cycles total; range, 0 to 28 cycles). Three patients (21.4%) completed six cycles of combination therapy (i.e., one patient at dose level 1 and two at dose level 2). These three patients then received 10, 22 and 28 cycles of exisulind alone. Reasons for removal from treatment included PD (eight patients), DLT (three patients), withdrawn consent (one patient), death unrelated to treatment (one patient), and serious adverse event unrelated to treatment (cerebrovascular accident in one patient).
Thirty phase II patients received a median 4 cycles of vinorelbine with exisulind (114 cycles total; range, 0.3 to 6 cycles) and a median zero cycles of exisulind alone (65 cycles total; range, 0 to 13 cycles). Seventeen percent (5/30) of patients withdrew from treatment before completing cycle 2 because of declining PS and/or treatment intolerability. Forty percent (12/30) of patients completed the initial six cycles of vinorelbine with exisulind. Eleven of these patients continued exisulind alone (median 4 cycles; range, 2 to 13 cycles). Reasons for stopping treatment included PD (25/30 patients), declining PS (two patients), withdrawn consent (one patient), death unrelated to treatment (one patient), and grade 3 peripheral neuropathy (one patient). Vinorelbine dose intensity was 75.5% of planned (median, 75%; range, 25 to 100%). Examination of available exisulind pill calendars for the patients treated at the University of Wisconsin suggested that compliance was good.
Table 2 summarizes phase I toxicities. Sixteen (10%) of 165 planned vinorelbine doses were held and 37 (22%) were reduced because of grade ≥ 2 neutropenia. One patient had neutropenic fever (grade 4). Toxicity attributable to exisulind was infrequent. Liver function test elevation was ≤ grade 2 except for one occurrence of grade 3 ALP elevation. One incidence of grade 3 diarrhea was reported. One episode of grade 3 constipation occurred, attributable to both drugs. Exisulind was held for 12 (5%) of 240 planned weeks of administration and dose reduced for nine (4%).
Table 3 summarizes phase II toxicities. Fourteen percent (62/444) of vinorelbine doses were held and 19% (84/444) were reduced because of neutropenia. Two patients (7%) had grade 3 neutropenic fever. Toxicities attributable to exisulind were infrequent. One episode, each, of grade 3 ALP and grade 3 AST elevation occurred. Four patients experienced grade 3 constipation. Out of 704 planned weeks of administration, exisulind was held for 16 weeks (3%) and dose reduced for 75 weeks (11%). Toxicities observed during 65 cycles of exisulind maintenance were grade ≤ 2 except for one incidence of grade 3 anemia and one episode of grade 3 neutropenia.
By January 2008, with a median follow up of 11.6 months (range, 0.4 to 54.5 months), all patients had died. Table 4 summarizes patient outcomes.
By January 2008, with a median follow up of 9.6 months (range, 0.3 to 61.6 months), 93.3% of patients had died. Table 4 summarizes patient outcomes. Five patients withdrew consent before completing two cycles due to decline in PS (three patients), grade 3 constipation (one patient) and progressive dyspnea (one patient). Reasons for stopping treatment in the other 25 patients included PD (24 patients) and grade 3 neuropathy (one patient). No CRs were seen. One patient experienced a PR, yielding an objective RR of 4.0% (95% CI: 0.1–20.4). The median duration of SD was 6.9 months. The median TTP was 4.7 months (95% CI: 3.1–9.3) and the median OS was 9.6 months (95% CI: 6.6–19.1). Figure 1 and Figure 2 are the Kaplan-Meier curves for TTP and OS, respectively.
Exisulind is a well-tolerated11 orally available pro-apoptotic agent6 with preclinical activity in NSCLC.8–10 Vinorelbine is the only drug shown to improve quality of life and survival as a single-agent in the first-line treatment of elderly patients with advanced NSCLC.4 Therefore, it was reasonable to assess these agents together.
Treatment in our phase I population yielded an MTD of 25 mg/m2/week of intravenous vinorelbine with 125 mg of oral exisulind twice daily continuously on a 28-day cycle. DLTs included constipation, diarrhea and febrile neutropenia. The phase II median TTP was 4.7 months (20.4 weeks) and the phase II median OS was 9.6 months (41.7 weeks). Our phase II primary endpoint was met, in that the median TTP exceeded 13 weeks. Neutropenia was the predominant toxicity, although neutropenic fever was rare. The median age of our patients was 78 years.
This is the first clinical study of exisulind with vinorelbine. Four other phase II studies combining exisulind with cytotoxic agents for the treatment of advanced NSCLC have been reported. Masters17 and Jones15 evaluated first-line exisulind combined with carboplatin/gemcitabine and carboplatin/docetaxel, respectively. Hoang12 and Weiss19 assessed second-line exisulind combined with gemcitabine and docetaxel, respectively. The results of these four studies were similar to what we would expect with their respective cytotoxic agents alone. In each, exisulind did not worsen outcomes or exacerbate toxicity. These studies' findings are in line with others in which a targeted agent, such as erlotinib,16 or a matrix metalloproteinase inhibitor,17 was combined with cytotoxic agents for the treatment of advanced NSCLC. The notable exception to this record is the prolongation of survival resulting from the addition of bevacizumab to cytotoxic agents.22, 23
Our efficacy results compare favorably with those of prior single-agent vinorelbine studies treating advanced NSCLC in the elderly. In a phase II study by Gridelli, patients at least 70 years of age with stage IIIB-IV NSCLC and an ECOG PS ≤ 2 were treated with first-line vinorelbine (30 mg/m2/week).13 The median age was 73 years and median ECOG PS was 2 (22/43 patients). Median TTP was 11 weeks and median OS was 36 weeks. A fair assertion when comparing this study with ours is that our patients were "fit elderly" with a median ECOG PS of 1. Nonetheless, the finding in our elderly phase II population of a median TTP of 4.7 months and a median OS of 9.6 months is provocative when compared to single-agent historical control.13 A randomized trial of vinorelbine with and without exisulind would be necessary to identify any clinical benefit in adding exisulind.
It is unclear why the results of our combination study incorporating exisulind yielded more favorable efficacy results than seen with prior exisulind combination studies in advanced NSCLC.12, 15, 18, 19. Although small in number, our patients were selected from multiple sites in our academic-community network. In addition, there do not appear to be significant discrepancies between our eligibility criteria and those from the other studies.16–19 Our findings are consistent with the prior exisulind studies, in that the addition of exisulind to a cytotoxic regimen did not appear to exacerbate toxicity. Although preclinical evidence to date suggests a lack of potentiation between exisulind and cytotoxics,20 our favorable experience with this combination prompts us to consider the use of pro-apoptotic agents in NSCLC worthy of further study.
The predominant toxicity in our patients was neutropenia attributable to vinorelbine. This was expected.4, 21 Nearly half of phase II patients experienced grade ≥ 3 neutropenia. However, neutropenic fever was uncommon. Prophylactic G-CSF support may have been useful in this setting to avoid treatment delay and dose reduction. Prophylactic pegfilgrastim starting with the first cycle of chemotherapy reduced the rate of neutropenic fever and hospitalizations in a randomized trial of 852 patients at least 65 years old.22 Since the initiation of our study, several organizations23–25 have recommended consideration of prophylactic G-CSF in elderly patients receiving standard-dose myelotoxic chemotherapy for whom neutropenia is expected.
The addition of exisulind to vinorelbine did not worsen toxicity in our patients. This is evidenced by the fact that 40% of our phase II patients completed six cycles of combination treatment. Additionally, in 175 phase II cycles of exisulind as part of combination therapy or as maintenance, exisulind-related toxicities were ≤ grade 2 in all but two cases (grade 3 ALP and grade 3 AST elevation). This profile is similar to that seen in a phase I study by von Stolk of single-agent exisulind in patients aged 18–45 years with FAP and subtotal colectomy.11 Here, there was only one grade ≥ 3 event (elevated alanine aminotransaminase) over approximately 108 cycles. We did not perform pharmacokinetic analyses. Therefore, one may theorize that the von Stolk study found a higher MTD because of an undetected interaction between exisulind and vinorelbine. However, it is also possible that our patients, who had intact colons, had greater resorption of exisulind leading to a prolonged residence time.26, 27
It is noteworthy that among our 30 phase II patients, eight developed grade 3, and one developed grade 4, dyspnea. Dyspnea is a nearly ubiquitous symptom in this population, in whom pleural effusions, pulmonary infections, pulmonary emboli, atelectasis, emphysema, anemia, cardiovascular disease, and prior treatments with radiotherapy are frequent.28 For example, Gridelli et al. reported a baseline incidence of dyspnea of 67% in their elderly cohort.3 Dyspnea is not a known adverse effect of exisulind, and prior evaluation of vinorelbine in the elderly do not report the incidence of dyspnea during treatment.4, 11, 13 It does not appear that exisulind contributed to the worsening of dyspnea in our patients.
Strengths of this study include its novelty as the first clinical study of vinorelbine with exisulind and its focus on older patients. Additionally, the conduct of this trial in both the academic and community settings may provide less bias in patient selection and a more realistic profile of toxicities and patient outcomes.
There are several limitations to interpreting this study. First, we did not use a uniform method of classifying comorbidities and functional impairment.29–33 We relied on ECOG PS3 in determining eligibility. As has been documented, the use of ECOG PS alone may not be the best way to assess the functionality of the elderly.34
Second, pharmacokinetic analyses were not conducted. Pharmacokinetic studies in elderly cancer patients have provided conflicting results, including reports analyzing vinorelbine.35–37 To our knowledge, no data exist concerning the clearance of oral exisulind in the elderly. However, Sitar found no differences in the clearance of sulindac sulfoxide, a prodrug of exisulind, when comparing elimination data from young, healthy individuals with those older than 65 years taking 150 mg twice a day.38 The type, frequency and severity of our phase II patients' toxicities were in line with our expectations. This observation implies there is low likelihood of significant pharmacologic interaction.
Third, 30% of our phase II patients presented for first-line chemotherapy after prior surgery, and 37% after prior radiation. This may indicate that our cohort carried a more favorable prognosis and may have contributed to our provocative efficacy outcomes.
Last, most of our patients had a PS of 1, and only two of 30 had a PS of 2. Therefore, our results are confined to the "fit elderly" and may not generalize to a broader geriatric cancer population.
We demonstrate that a first-line regimen of vinorelbine/exisulind was reasonably well tolerated by an older cohort of patients with advanced NSCLC. Median TTP and median OS were prolonged compared to historical control. We conclude that this combination is safe, appears to have activity in patients at least 70 years of age with advanced NSCLC and a PS ≤ 2, and that the use of pro-apoptotic agents in NSCLC warrants further investigation. At present, however, the study sponsor does not plan further clinical development of exisulind.
We thank our patients and their families for their participation and support. We acknowledge funding from National Institutes of Health grant T32 CA009614 Physician Scientist Training in Cancer Medicine (S.A.), grant P30 CA14520 (K.M.K.) and OSI Pharmaceuticals. COI disclosure: K.M.K serves as consultant to OSI on an unrelated project, not involving exisulind.
We acknowledge funding from grant P30 CA14520 (K.M.K.) and National Institutes of Health grant T32 CA009614 Physician Scientist Training in Cancer Medicine (S.A.) and OSI Pharmaceuticals (Melville, NY).
PubMed Central Canada is a service of the Canadian Institutes of Health Research (CIHR) working in partnership with the National Research Council's national science library in cooperation with the National Center for Biotechnology Information at the U.S. National Library of Medicine(NCBI/NLM). It includes content provided to the PubMed Central International archive by participating publishers.


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UCB is a global biopharmaceutical company. We focus on discovering and developing innovative medicines and lateral solutions that can transform the everyday lives of people with severe diseases of the immune system – or the central nervous system.
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Loved the Serenade!!: Serenade of the Seas Cruise Review by newlu
Overall Member Rating
Loved the Serenade!!
Destination: Southern Caribbean
Embarkation: San Juan
Since I am always on this board, my turn to write a review. I have cruised quite a few times with Royal, but never on the Radiance class, and always left from Florida. Since it was just me and my boyfriend, not with our teenage son, we figured we would try the Serenade with all the beautiful ports!
We flew in SJ 2 days prior, but got to our hotel around midnight (Sheraton Old San Juan, got it for $100 per night on Hotwire) for that price, it was great, but would never pay $250, so noisy... We toured San Juan and then went for diner at El Convento, tapas and sangrias, really good!
We boarded the ship around 12:30pm, quite easy, not hectic like Miami. Loved the ship, its decor, its size, and of course, the wonderful staff.
The whole week was great, we had balcony 9576, hump cabin, loved the balcony!
The food was pretty good, we ate in the dining room 5 nights, and we did Chops and Portofino. Loved Chops, as always, Portofino left to be More desired, but we must admit, we were not that hungry. We had breakfast in the Windjamer 4 mornings and dining room the 3 others, prefer the dining room, by far.
The service on this ship is really good, you are not even sitting down at the buffet at lunch, they are already there to take your other for drinks.
First cruise that the waiters at the pool do not even bother you, they pass, you ask them if you want something.
The cruise director was quite good.
We would definately cruise on the Serenade again, and highly recommend it. Less
Published 02/01/11
Cabin review: D29576 Superior Ocean View Stateroom with Balcony
We had booked this cabin 10 months prior, loved it, best cabin for us so far, just perfect! 9576 on the hump.Read All Superior Ocean View Stateroom with Balcony (D2) Reviews >>
Port and Shore Excursions
Read Cruise Critic's Serenade of the Seas Review >>
Vista and jeep tour
Staff Makes The Trip!
Awesome family cruise, great i...
Service was excellent, food an...
Easy to get around ship and gr...
Magnificent Baltic Cities
Wonderful smaller ship 5 night...
Nice vacation, but chose anoth...
Cuba for the first time
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The Mandatory Provident Fund Schemes Authority has released performance figures of its Default Investment Strategy (DIS) - dubbed the fund for lazy people.August 17, 2017
The online registration for the Standard Chartered Hong Kong Marathon 2018 began on Aug 16! Here are key points to note for the annual event.August 16, 2017
The government has announced the first representative list of Hong Kong's Intangible Cultural Heritage. It will help the government conserve and promote them.August 16, 2017
Piano Fong turns old Kwun Tong factory into 24-7 venues for space-starved artistes.August 14, 2017


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Yinchorr was a planet governed by the Yinchorri High Command. The planet was one of the principal participants in the Yinchorri Uprising, fighting against the Galactic Republic and the Jedi Order, and was the location of the Battle of Yinchorr in 23 BBY.[1]
Sources Edit
- The Alternative Essential Guide to Characters (First mentioned)


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March 28: At least two persons were killed and four others were injured when Bangladesh Rifles (BDR) personnel opened fire on unarmed villagers engaged in repairing a road near the Indo-Bangla border at Jamaldahabalapukuri, around 70 km from Cooch Behar town, this afternoon.
The arrival of a large contingent of the Border Security Force (BSF) two hours later did little to diffuse the simmering tension that gripped the border hamlet in the Mekhliganj police station area. Police said most of the villagers have fled for fear of the BDR.
Reports on the number of deaths are conflicting as the figures released by the police is one more than those put out by the BSF. Senior BSF officials have put the toll at two. Four of the injured have been admitted to the district hospital in Jalpaiguri.
Cooch Behar police superintendent Jagmohan said the injured were first taken to the subdivisional hospital in Mekhliganj, 15 km from Jamaldahabalapukuri, and later shifted to Jalpaiguri.
Police said two unidentified persons died on the spot. The third, identified as 50-year-old Mohammad Manglu, died at the Jalpaiguri hospital in the evening.
Mustafa Hussain, 18, Abdul Jabbar Ali, 65, Hamidul Islam, 28, and Jamilur Hussain, 25, are the others who have been admitted with bullet injuries.
Subdivisional officer of Mekhliganj Gurudas Sarkar said the body of Jasimuddin, 40, which was taken away by the BDR, will be handed over to the BSF tomorrow.
Dhirendranath Roy, one of the men accompanying the injured to Jalpaiguri, said about 100 men were levelling a kutcha road along the border under the Sampurna Grameen Rozgar Yojna.
'The work was being supervised by the Kuchlibari gram panchayat (see map). Suddenly, the BDR asked the men to stop working. That was in the morning. The Bangla force then had a discussion with the BSF and work resumed. But in the afternoon, there was a change in shift and the new group of BDR personnel entered into an altercation with the workers. They even beat them up with lathis and then suddenly started firing,' Roy said. 'They fired on unarmed people.'
'What worries us is that despite the BSF outpost located nearby, we feel insecure,' Roy said.
S.S. Sandhu, the additional deputy inspector-general of the BSF, when contacted in Siliguri, said the border force has already registered its protest against the unprovoked firing.
'We have already held one flag meeting with the BDR at the spot. We have also deployed jawans in the area so that the BDR does not cause any more problems for villagers. Our men from Jhikabari reached the spot soon after the incident,' Sandhu said.
The BSF official put the death toll to two. He said one person had died on the spot and the other at the Jalpaiguri hospital.
Jalpaiguri MP Minati Sen visited the injured at the hospital, where she met the shocked wife and son of Mohammad Manglu, who were sitting on the floor and crying. 'Parliament is no longer in session, but I will write to the Union home minister complaining about this heinous crime committed by the BDR,' Sen said.
Sarkar and other senior officials from the Cooch Behar district administration had left for the spot in the afternoon.


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[XP] Re: in-memory Repository & Object Prevalence technology
Expand Messages
> --- Jeff Grigg wrote:--- "J. B. Rainsberger" <jbrains@r...> wrote:
>> Well, ditch the database, and just take one simple step
>> to full blown Object Prevalence technology, possibly
>> with Prevayler. ;->
> If it weren't for interoperation with other applicationsThat's perverse. Why would sensible people go through all the
> that demand RDBMS... I just haven't had a real project
> on which I've been allowed to try Prevayler.
trouble of building a proper three tier architecture, to separate
presentation, business logic, and database access implementations
from each other, and then blow it all by letting everyone else access
the physical database schema directly? Is there no sense in the
world? Sensible people would have applications talk to each
other "business layer to business layer" -- service-oriented
(And yes, I know all about it; it's something that I see happen *all
the time.* ;-)
(And, well, I haven't been allowed to try Prevayler either. )-:
- Adrian Howard wrote:
> On 17 Aug 2004, at 12:22, Ilja Preuss wrote:Yes, but I thought that we were talking about a test that was wrong. Not
> [snip]
>> It's certainly the case that without pairing/reviews I am more
>> likely to
>> *miss* tests - but I don't think that I get more *wrong* tests that
>> cancel out with wrong implementation...
> I think it could happen over time.
> - Lack of pairing might mean I miss duplication so a bit
> of business logic gets into foo and bar.
> - My acceptance test for the business logic only uses foo.
> - Later I change bar incorrectly, but the foo test still passes.
> False-pass for that bit of business logic.
sure wether that matters, though...
Cheers, Ilja
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Movietube App is a search engine for complete movies from YouTube movies. It capabilities the modern trailers, films news, opinions, film solid, and movies team with all of the state-of-the-art updates from showbox app. This app is a domestic for film enthusiasts, who can locate their preferred and contemporary freeing indicates at one vicinity. It notifies you with present day updates and brings you whole YouTube films and Showbox Movies effortlessly. Movietube app may be downloaded from the Android Google play shop and additionally it's miles to be had on IOS gadgets. Find a selected movie in Android cellular may be very difficult and streaming them comes to a massive problem.
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Thank you for reading Movie Tube app download guide for Android and IOS platforms respectively. Hope you like our article and make sure to share it online with all your friends.


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Event Gallery produced the LMFF National Graduate Showcase Presented by Sportsgirl featuring emerging designers Bernadette Francis, Natasha Fagg, Cesar Chehade, Jack Hancock, Kara Liu and Nixi Killick from RMIT, Courtney Holm, Karen Yang and Kathleen Choo of University of Technology Sydney, and Hayley Elsaesser, Koren Wheatley and Monique White of the Queensland University of Technology.
Australian fashion darling Sportsgirl continued their blazing trial of support for up-and-coming fashion designers when they presented the National Graduate Showcase for L'Oreal Melbourne Fashion Festival, introducing 12 of the hottest new designers. Selected from 77 applicants, the fashion graduates, hailing from the design institutions of RMIT, Curtain and the University of Technology in Sydney, showed that the future is bright for Australian design through their quirky, fun, and creative designs. The graduates embraced block colour, patterns, sharp tailoring and chic silhouettes, with each collection being a unique nod to the designers inspirations.Sassy Bella
Executive Producer Geraldine Frater-Wyeth Stylist Kate Gaskin Music Director Will Pyett Head Dresser Megan Anderson Hair Director Brad Ngata Event Photography by Lucas Dawson


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Mickey's Toothache is an unproduced animated short that was to have been released in 1938. Artwork for the cartoon was done by Disney storyman Ferdinand Horvath.
Mickey ends up in the office of a sadistic dentist played by Pete. After being put on laughing gas, he finds himself in a nightmarish world of monstrous dental equipment and evil teeth.


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Now those of you who know me well, know that I like a really good curry and not only does it need to be a good curry but it needs to be a very spicy curry too, but that's just my personal preference.
Living in Paihia in the Bay of Islands, we are very lucky to have 'Greens', an authentic Indian and Thai Restaurant offering specific chefs dependent on the cuisine that you prefer. Now I must admit that we eat there quite a lot, you could say too often if there is such a thing but when we want to get out of the editing studio at the end of the day, after very little debate we usually end up at our favourite Indian restaurant.
So we were thrilled when we heard that the owners were expanding their empire and opening up 'Indian Spice' in Mangonui. Now it couldn't get much better than that, our favourite Indian in one of our favourite places. We were very honoured that the owner invited up us to their opening yesterday and we weren't disappointed with the location, the ambience and the food. The building dates back to 1861 and has been decorated with a modern and tasteful design and now seats up to 32 diners.
One of the rituals in Hinduism when opening a new business is praying to' Ganesh', immediately recognizable as the elephant-headed God, He is the God of wisdom and learning as well as the remover of obstacles and consequently the sign of auspiciousness. Now the family gathered round and offered up their prayers and the owner asked if I would be kind enough to break a coconut open on the steps at the entrance. Now I was a little non plussed at first but found out that this is a common ritual in Hinduism too...coconuts are broken before an activity of any magnitude is undertaken. The only thing was that it must be broken in one hit and I must admit to a little nervousness...what if i didn't achieve it? I gave it my all, on the count of three, and the coconut smashed covering the owner and myself in coconut milk!! The coconut was then peeled out and cut into small slices and shared out to the small gathering. The significance is symbolic of annihilating the ego and humbling oneself before God. The actual 'doer' is God and humans are merely instruments in his hands.
The restaurant was alive with lots of the owners family, well wishers and local diners who had come in to try this tasty fayre. Everyone was chatty and happy and the buzz was abound that the food was indeed excellent. The Kashmiri naan was one of the best I have ever tasted and I can tell you I have eaten quite a few.
So we wish the owners all the best in their new venture, if you are ever up that way make sure you pop in, we can assure you, you won't be disappointed.
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How rich is Russell Crowe?
Russell Crowe Net Worth:
$75 Million
Russell Crowe Net Worth:
Russell Crowe Net Worth $75 Million
A New Zealand born celebrity, movie producer and musician, "Russell Crowe" is best known to the universe for his extraordinary performance as the 'Roman General Maximus Decimus Meridius' in 2000 historic epic movie 'Gladiator'. The gifted performer was created on 7th April, 1964 in Wellington, New Zealand. Russell began his career as a musician in early period of 1980s. In the age of 21, he returned back to Australia where meant to join 'National Institute of Dramatic Art'. He became the portion of the show until 1988. Then in 1988, he portrayed the character of Mickey in Australian production of 'Blood Brothers'. He further continued his performing career with appearing in the several television series like 'Neighbours' and 'Living together with the Law'. But before the production of the film began, he was hired for the film 'Blood Oath' which released one month before 'The Crossing'.
After getting in success in Australia, Russell Crowe was chosen to appear in 1993 film 'For the Moment'. In 1995, he starred in the film called 'The Quick and the Dead'. But his breakthrough performance came in the film 'Gladiator' where he received Academy Award as 'Best Actor'. His other noticeable parts came in the films like 'Robin Hood', 'The Next Three Days' and'The guy Together With the Iron Fists'. Besides his incredible performance in the film, he's also called god talented musician. In the year 2012, he's sung a tune in the film 'Les Miserables'. From his acting and music career, he's earned an estimated net worth sum of $75 million dollars.


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Cong leader, others cleared of rioting charges
Delhi Congress MLA Talvinder Singh Marwah and six others got a clean chit from a city court on Tuesday.delhi Updated: Mar 17, 2010 00:33 IST
Delhi Congress MLA Talvinder Singh Marwah and six others got a clean chit from a city court on Tuesday.
They were accused of rioting and injuring policemen during campaigning in the 1999 Lok Sabha elections.
A case was registered against Marwah and others alleging that the Congress leader had led a crowd of close to 700 people who had broken window panes of Sun Light police post here.
The crowd reportedly pelted stones as well, injuring two policemen.
"All the witnesses have stated that the accused (Marwah) was delivering provocative speeches and the crowd started shouting slogans but nowhere have they said anything about the exact words used," Additional Sessions Judge S C Rajan said.
The court absolved Marwah, the MLA from Jangpura, and others stating that the prosecution failed to prove as to how he had instigated the crowd.
It also noted that the prosecution witnesses could not name those who had pelted stones and injured the two Delhi police Constables on September 6, 1999, at Sriniwaspuri.
Out of the 15 prosecution witnesses, a Delhi police constable, who was injured in the incident, had turned hostile. The prosecution said the crowd, armed with rods and swords, was protesting the preventive arrest of Congress workers.


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I have been so busy lately that I have been missing all the fun with the photo challenges for a few weeks now, so I am thrilled that I can join in this week. My contribution is some artwork called Ghost of Smugglers Cove (image cropped for post) and the pirate, or should I say ghostRead More
I have a true appreciation for architecture, especially from times gone by. I took this photo as I was driving by and I have spent all morning trying to find out which church it is so I could share some of its history with you too. We were exploring around the Ludlow area in Shropshire, but we alsoRead More
The Idlewyld Inn, originally an old Victorian mansion built-in 1878, is still gracing London, Ontario with its grand presence after 135 years. Over the years it has been converted into luxury apartments, a nursing home and in 1986, to the distinguished Inn it is today. With most of its history and charm preserved, the InnRead More


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Ww Sweet Apple and Cheese Pancakes. 4 Pts.
Be the first to review
READY IN: 35mins
Recipe by seapard
From WW All-Time Favorites Cookbook.
See Discussion:
Ingredients Nutrition
- 5 teaspoons unsalted butter
- 1 apple, peeled, cored, and finely chopped
- 2 teaspoons sugar
- 3⁄4 low-fat buttermilk
- 1⁄4 cup Egg Beaters egg substitute
- 1 cup flour
- 1⁄3 cup whole wheat flour
- 1 1⁄2 teaspoons baking powder
- 3⁄4 teaspoon baking soda
- 3⁄4 teaspoon salt
- 1⁄2 teaspoon nutmeg
- 1⁄2 cup fat-free cottage cheese
Directions See How It's Made
- Melt 2 tsp butter in nonstick skillet over med. heat. Add apple and sugar. Cook, stirring, for 5 minutes. Transfer to a small bowl and let cool 5 minutes.
- Heat 3 tsp butter in microwave until melted. Whisk melted butter, buttermilk, and egg in large bowl; set aside. Combine flour, baking powder, baking soda, salt and nutmeg in another large bowl. Add flour to milk misture, stirring just until blended. Stir in apple and cottage cheese.
- Spray nonstick skillet with cooking spray and set over medium heat. Pour in batter by 1/4 cupfuls. Cook 3 minutes per side.


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Horseradish Mustard
A creamy mustard with a powerful horseradish kick. Wonderful with hot roast beef or on sandwiches.
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Cumbrian Hot Spot
Wow, Cumbrian Delights Chilli Jam certainly isn't for the faint hearted, not with its 31% chillies content. Add it into stir fries, have it on a bacon butty, some even have it on toast.


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How to buy SydneySide products?
SydneySide operates differently to other furniture retailers. We don't carry stock! As we manufacture each item locally in our own factory we are able to offer you choices that others can't.
Custom made – without the one off price!
SydneySide has developed a "supply on demand" furniture system. Our manufacturing is computer controlled, taking our existing designs and modifying them to your needs. That means we have the confidence that every time we make an entertainment unit, we know it is going to work. This way our furniture costs the same as if you purchased a stocked item.
Over 500 designs
With this system it is very easy for us to add designs to our range. We now have over 500 designs for entertainment units from small 1 meter entertainment units and shelves, to monster 6 meter wall installation and we are adding to these designs all the time. Still cannot find the right entertainment unit in our range? We will work with you from scratch to design your perfect entertainment unit.
Any colour
To go with our massive range we can make your entertainment unit in any colour or any finish! We already have a large range of standard polyurethane colours in flat, satin and high-gloss, complemented by a large range of laminates and veneers. However, if you have something truly special in mind, we are always happy to order it in.
Too much choice?
Sometimes too much choice can be a bad thing? It is daunting where to start and hard to work out what will be right for you. That is where we come in. With years of experience in designing entertainment units for our customers, our designers will be able to guide you through the process. Just bring in:
- The length of your wall, or a photo, or the plans of your living room.
- An idea of the equipment it has to hold.
- We will do the rest.
We can even show you a 3d image of what your entertainment unit will look like in your home so you can be confident in making the right choice.
Come and talk to one of our designers about your perfect entertainment unit today.


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A criminal appeal is a formal request to rehear a case that has already been decided -- a request that a new court reconsider the decision of the first court. When one or both sides of a case that has already been decided think there was a mistake made at trial, they can file an appeal. An appeal is entirely different than a jury trial. There is no testimony taken. The court of appeals decides the case entirely upon the written briefs filed by your attorney and the offie of the Attorney General who represents the prosecution and asks that the conviction be upheld.
Koosharem is a town in Sevier County, Utah, United States. The town's name is said to come from an edible tuber, a traditional staple food for the area's Native Americans. The population was 276 at the 2000 census. A 2008 annexation increased the population to an official estimate of 400.
Criminal Appeals Law Lawyers In Koosharem Utah


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Holiday Parks
Bordering the southern fringe of the world famous Snowdonia National Park, Ceredigion is a beautiful country in West Wales stretching from the stunning Cardigan Bay on the west coast to the sheltering Cambrian Mountains in the east. The 50 miles of coastline is pocketed with stretches of sandy beaches and the clear transparent sea off the coast is a popular summer residence for bottlenose dolphins. Take a boat trip from Cardigan Bay and see if you can spot them!
Aberystwyth is definitely worth a visit if not for the vibrant shops, beautiful beaches and working harbour than for the stirring castle and unique electric cliff railway crawling up the hillside rewarding you with the most spectacular panoramic views of not only Cardigan Bay, but the 26 mountain peaks spanning most of Wales. Just along the coast from Aberystwyth, Aberaeron is a hidden gem along the west coast of Ceredigion, with its independent shops, pretty colourful cottages, peaceful working harbour and breath-taking surrounding scenery.
When you've explored the coastline head inland and discover the Teifi Valley or Aeron Valley for some fantastic walks and cycling opportunities taking in the stunning sights and spotting the local wildlife. Catch the Vale of Rheidol Railway from Aberystwyth to Devil's Bridge Falls - a spectacular natural wonder in the Rheidol Gorge - and be blown away by the unique waterfalls and magical scenery.
Haul -y- BoreAberystwyth, Mid Wales
Ty ByreAberystwyth, Mid Wales
Top 10 things to do in North Wales
Top gardens in Wales to visit this spring
Romance in the Welsh hills
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Stay in Media Limited is registered in England and Wales. | Registered office: Grenville Wharf, The Quay, Bideford, Devon, EX39 2HW | Company No. 07391123 | VAT reg: 107706918


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Mr. Peter "Pete" Cooper, in his current position is responsible for developing new business opportunities for Cornerstone with medically related product and service vendors, medical practices and medical facilities.
Experienced Sales and Marketing Professional with expertise in business development in the Cardiology and Imaging Medical Equipment industry. Twenty plus years of strong industry contacts and relationships, a bottom line manager.
Whether your issues are cash flow, revenue recognition, depreciation, operating expenses, etc., Ray has first-hand knowledge of all of these topics so please allow Ray's experience work for you to design the best leasing program for you.
She has spent the past 10 years in an executive position as both a CFO and CEO. She spent the majority of her career at one of the largest not-for-profit healthcare systems in the United States


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Today marks the 59th observance of the National Day of Prayer. Created in 1952 and signed into law by President Harry Truman. Prior to the nation's founding, the Continental Congress issued a proclamation recommending "a day of publick humiliation, fasting, and prayer" be observed on July 20, 1775 During the Quasi-War with France, President John Adams declared May 9, 1798 as "a day of solemn humiliation, fasting, and prayer," during which citizens of all faiths were asked to pray "that our country may be protected from all the dangers which threaten it". On March 30, 1863, President Abraham Lincoln issued a proclamation expressing the idea "that the awful calamity of civil war, which now desolates the land, may be but a punishment, inflicted upon us, for our presumptuous sins", and designated the day of April 30, 1863 as a day of "national humiliation, fasting and prayer" in the hope that God would respond by restoring "our now divided and suffering Country, to its former happy condition of unity and peace". He went on to say, "...it is the duty of nations as well as of men, to own their dependence upon the overruling power of God, to confess their sins and transgressions, in humble sorrow, yet with assured hope that genuine repentance will lead to mercy and pardon; and to recognize the sublime truth, announced in the Holy Scriptures and proven by all history, that those nations only are blessed whose God is the Lord."
In more recent history, the idea of an annual National Day of Prayer was introduced by the Rev. Billy Graham, who suggested it in the midst of a several-week crusade in the nation's capitol. Members of the House and Senate introduced a joint resolution for an annual National Day of Prayer, "on which the people of the United States may turn to God in prayer and meditation at churches, in groups, and as individuals."
On April 17, 1952, President Harry S. Truman signed a bill proclaiming a National Day of Prayer must be declared by each following president at an appropriate date of his choice. In 1982 a conservative evangelical Christian organization called the "National Prayer Committee" was formed to coordinate and implement a fixed annual day of prayer for the purpose of organizing evangelical Christian prayer events with local, state, and federal government entities. In his 1983 declaration, Ronald Reagan said, "From General Washington's struggle at Valley Forge to the present, this Nation has fervently sought and received divine guidance as it pursued the course of history. This occasion provides our Nation with an opportunity to further recognize the source of our blessings, and to seek His help for the challenges we face today and in the future." In 1988, the law was amended so that the National Day of Prayer would be held on the first Thursday of May.
Now today, in our history, just this year in fact, a federal judge from Wisconsin has ruled the National Day of Prayer, unconstitutional. On March 1, 2010 U.S. District Judge Barbara Crabb stated: 'In my view of the case law, government involvement in prayer may be consistent with the establishment clause when the government's conduct serves a significant secular purpose and is not a "call for religious action on the part of citizens." McCreary County, Kentucky v. American Civil Liberties Union of Kentucky, 545 U.S. 844, 877 (2005). Unfortunately, (section) 119 cannot meet that test. It goes beyond mere "acknowledgment" of religion because its sole purpose is to encourage all citizens to engage in prayer, an inherently religious exercise that serves no secular function in this context. In this instance, the government has taken sides on a matter that must be left to individual conscience. "When the government associates one set of religious beliefs with the state and identifies nonadherents as outsiders, it encroaches upon the individual's decision about whether and how to worship." McCreary County, 545 U.S. at 883 (O'Connor, J., concurring). Accordingly, I conclude that (section) 119 violates the establishment clause.'
It saddens me deeply to see this blessed country that I SO love, turning away from that which made us the great and blessed country that we have been. Contrary to what many would want us to believe, this country was founded on Christian beliefs and values. If you don't believe me, just read the Declaration of Independence. The Declaration contains five references to God - God as supreme Lawmaker, God as Creator of all men, God as the Source of all rights, God as the world's supreme Judge, and God as our Protector on whom we can rely.
The very idea that a government or President, through acknowledging the importance of prayer and humbling of ourselves in a National way, can or has caused 'concrete injury' to anyone, is beyond me. If I don't like a book, TV show or movie, I choose not to read/watch it.
2 Chronicles 7:14 - If my people, who are called by my name, will humble themselves and pray and seek my face and turn from their wicked ways, then will I hear from heaven and will forgive their sin and will heal their land.
Pray with me, wont you?
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Responsible Dog and Cat Training and Behavior Solutions, LLC offers Service and Therapy Dog Training. Feel free to contact us for more details. Use the "Contact Us " form. We look forward to helping you with all your dog and cat needs.
We're located between Sarasota and Manatee County. We serve Bradenton, Ellenton, Parrish, Lakewood Ranch, Sarasota, Venice, Long Boat Key, Nokomis, Osprey and surrounding counties.


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Celicakes is a cake store in Desa Sri Hartamas, it was first founded on 12 June 1997 in Kuala Lumpur. We are located at 66,Jalan 27/70A Desa sri Hartamas 50480 Kuala Lumpur.
We specialize in custom design cakes, cupcakes & cookies for your Birthdays, Weddings and any other celebration. We also make custom flavored cakes, pies, tarts, pastries, etc. We here at Celicakes always believe in using only the best quality ingredients to make cakes to our lovely customers.
Visit our facebook page at https://www.facebook.com/celicakes.com.my