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September 3, 2014 at 4:30pm to November 5, 2014 at 6pm – Online By the summer of 2015, LEED for Homes version 4 (V4) will be in full swing. Project teams will no long be able to register homes, multi family or mixed use buildings under the 2008 or 2009 rating sys… Organized by Brett Little | Type: webinar, series
September 10, 2014 from 12pm to 1pm – Online "When my wife Kelly and I bought our 110 year old Folk-Victorian home in Ann Arbor's Old West Side Historic District, it was a dream come true: drafty old windows, lead paint, zero insulation, a half… Organized by Brett Little | Type: webinar
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TEMPLE — The Texas Department of Transportation takes measures to avoid creating hazardous driving situations.
The Texas Department of Transportation lowers the speed limit on overnight main lane closures to 60 mph, said Jodi Wheatley, Interstate 35 specialist for TxDOT.
The speed limit also decreases to 60 mph in places where concrete barriers are on both sides of the lanes and the shoulder is reduced to less than 10 feet wide for a mile or more.
"The lanes themselves are exactly the same size they always were. They just look narrower because you now have the barrier in your field of vision," Wheatley said.
When possible, extra room is allowed between the lanes and the walls, Wheatley said.
"The fact that the highway is being expanded means that sometimes we are going to be working really close to traffic, and in Temple, you'll probably see a lot of that since the new lanes are being constructed in such a highly built-up area. That requires the use of barriers that can do the job of controlling the vehicles in the event of a crash."
Barrier walls have two purposes: to keep traffic in a limited area so construction workers are protected from traffic coming off main lanes into work zones and to stop drivers from leaving the road and crashing into machines or a concrete culvert in a construction area — and to keep them from going into the opposite lanes of travel into incoming traffic.
"They are designed to cause a vehicle to come back into the lane it tried to leave, helping to prevent rollovers when a vehicle would otherwise have hit the median or slope and tipped," Wheatley said.
John Habermann, a spokesman for the A&M Transportation Institute, which consults with TxDOT on construction and does research on crashes and traffic flow, said many times the construction work creates drop-offs varying from a few inches to several feet, and the barriers are needed to keep travelers from going off the edge of the road.
Currently there are 200 lane miles of I-35 under construction in the Waco District, and only 11 percent — or 22 miles — of that are lined with concrete barriers.
New speed limit signs with red borders and additional speed display signs alert the drivers to the 60 mph speed limit in the barrier areas.
TxDOT knows about the ponding problem on southbound I-35 south of Salado, Habermann said, adding there are plans to fix that section once the weather stabilizes and warms up. At that time, a work schedule will be publicized.
More speed limit signs are being added where the speed limit is reduced to 60 mph and signs will be put on both sides of the highway at each location in case a driver can't see the sign because it's blocked by an 18-wheeler in the lane next to their vehicle, Wheatley said.
Warning system
One of the new additions for overnight lane closures will be the end-of-queue warning system. The system will have portable rumble strips to get a driver's attention followed by a lighted sign informing motorists about the road condition ahead.
Two radar speed trailers will show drivers what their current speed is compared to the actual speed limit, Wheatley said.
Habermann said TxDOT increased the bridge height signs for large trucks, too.
Sometime this year, TxDOT will be part of a pilot program that will test variable speed limits to see if that gets a driver's attention earlier and better and works to slow traffic.
"We are confident more ideas will rise as brainstorming and research continue," Habermann said.

subset: commoncrawl


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From Post staff reports
"I just couldn't stop thinking about the place," said Edie Oates explaining why she has agreed to return in a management role to Lebanon's Snow White Drive-In restaurant.
She and owner Anthony Leath are bonding on a joint mission to turn back the pages of time and to return this once prominent Lebanon night spot to its renowned place of glory for those who still have a craving for its ice cream sundaes, milk shakes, hamburgers, barbecue and the like.
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Heavy duty edge stitching through out


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This week's literary controversy is about an inflammatory article that appeared in Slate, dissing "YA" (young adult) fiction, in the wake of the release of the summer blockbuster movie The Fault in Our Stars, which is based on a massively successful novel of the same name.
The essay, by Ruth Graham, was titled "Against YA." It revealed that large numbers of novels marketed at teenagers are actually being consumed by adults, and criticized those adults for indulging in childlike pleasures. "The enjoyment of reading this stuff has to do with escapism, instant gratification and nostalgia," she wrote.
The response was quick, indignant, derisive and almost universal. Everybody who has ever enjoyed a science-fiction or detective novel read the piece as an attack on genre fiction generally and voiced rage at the elitism of the "literary" writers who want to take all the fun out of the world and who are trying to tell people what they should and shouldn't enjoy. In this newspaper, Erin Anderssen penned a defence of the pleasures of teen fiction, especially when one is around teenagers, and of reading widely in general.
It's a tough argument to address because no one, so far, has attempted a plausible definition of what YA is. It is not merely sci-fi or fantasy or romance; all those genres exist within it. If anything, Graham's jeremiad was against a particular narrative tone rather than a genre in the conventional sense.
What makes a publisher decide to market a book to a particular audience is not the subject matter but the style. The only thing that unites books in this category is a certain straightforward diction. The narratives, on the whole, are chatty and explanatory. The only thing that makes a book YA is that it is about teenagers and it is written in a very conventional, non-artsy, non-pretentious way. YA is not the place for the oblique or the cryptic. If it is in any way experimental in form, it is not YA.
At least that's the only consistent criterion I can make out. There are many canonical adult stories about teenagers – Romeo and Juliet being the most famous; The Catcher in the Rye a close second – that were never sold as being for teenagers. The novel Maidenhead, by Tamara Faith Berger, is about a teenage girl discovering her sexuality, and it could never be called YA, not just because it is sexually explicit, but because its language is impressionistic and unusual. It's an artistic experiment. The artistic experiment is the opposite of YA.
The YA category is an entirely new one, and seems to have more to do with readability than with age group or theme. The adult YA readers I know do actually consistently say that they are looking for an easy read, a fun read, an unchallenging read. And they are unashamed of seeking the light and the fun, even defiant about it – populism seems to many like a non-conformist position.
This is one argument that recurs, and I think it is indicative of a larger movement among young intellectuals that privileges the demotic over the obscure. Repeatedly, the outraged fans of YA are saying: It is wrong to tell me what I should and shouldn't enjoy. There is nothing wrong with enjoyment.
Increasingly, to dismiss any popular artistic style is seen as the worst kind of snobbery. And snobbery, it goes without saying, is unacceptable in a diverse and democratic world.
This stance was best articulated in Carl Wilson's brilliant examination of the nature of aesthetic snobbery, Let's Talk About Love, a book about trying to like the music of Celine Dion. Wilson begins by confirming that a complete openness to every genre is seen, among pop-music culturati, as a necessary condition for any criticism; that a highly eclectic taste is seen as the mark of the sophisticated and fashionable person.
This is part of the tenor of the times, and it is not without its unease. It makes some critics distinctly nervous. The determined appreciation for the commercial and formulaic is one step away from insisting that every cultural product has equal value.
I see this insistence on kindness and openness as part of broader ideological positions: It is a part of the same youth culture that demands highly sensitive language to describe gender choices and wants trigger warnings on upsetting poems and reacts indignantly when told that teenage girls might ever be wrong about anything. It's a culture of inclusion.
Just today, I read a blog post that's going around by a humorist named John DeVore. It's going around because it's mildly funny. It's about how much he loves Broadway musicals and how the people who disdain them are "dead inside." It says musicals are deserving of the snobs' respect because they are honestly and unironically emotional. "Musicals don't get respect from most people, and that's fine. I don't watch hockey, and that's okay. I don't talk trash about it."
I mention this piece of ephemera because it's so typical, such a perfect encapsulation of a philosophy of aesthetic judgment that is so current it can only be called hipster. "Love what you love," he writes. "This is a truth you can only read on a non-ad-supported Internet digital web blog platform. I'm not selling anything."
Here you have all the vectors of hipster judgment converging: the proud embrace of kitsch; the plea for universal acceptance of every emotional expression; the vow of non-capitalist authenticity; and a vague sense of non-conformism or rebelliousness. (It's tongue-in-cheek, of course, pervasive ironic self-deprecation being another part of the ethos.)
Sure, love what you love, of course. But please don't try to argue that criticism of what you love can only be motivated by some sort of classist snobbery, or that any criticism that relies on aesthetic judgment is in some way elitist.
The defenders of YA are willfully, I think, ignoring some important points. It is not ridiculous to point out that the primary appeal of this literature lies in its artistic conservatism. That seems like a legitimate troubling point to me. Nor is it mean or small-minded to criticize art, for as long as there has been art, there has been criticism.
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The Beet Goes On - Ep. 474
The Beet Goes On - Ep. 474
Record date: Aug 18, 2010
Irwin Goldman, professor, Department of Horticulture, UW-Madison. Irwin Goldman provides a historical account of the table beet, explaining how this and other root vegetables fits into the discussion of immigration and social justice. In this account, he also touches on the beet's health benefits.
University Place Campus:
University Place Lecture Series:
University Place Subjects:


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ATLANTA — Durant Brooks is the best punter in Georgia Tech history, and it's not even close.
He'll soon learn if he's considered the best punter in the nation.
Brooks enters his final regular-season game with a career average of 45.44 — more than four yards better than the old school record of 41.41 by Rodney Williams.
What's more, Brooks is finishing his career on a high, coming off his best game and ranking as a finalist for the Ray Guy Award given to the nation's top punter for the second straight season.
Last year, Brooks finished runner-up to Baylor's Daniel Sepulveda for the Ray Guy Award.
This year, Brooks has joined Cincinnati's Kevin Huber and Toledo's Brett Kern as the finalists. The winner will be announced at a Dec. 6 awards ceremony in Orlando.
Brooks, from Macon, says he'll feel state pride on Dec. 6 just as he will on Saturday when Georgia Tech plays host to Georgia.
Brooks considers Ray Guy, from Thomson, to be a mentor. He attended Guy's kicking camp and says he wants to bring the award named for Guy back to the former Oakland Raiders star's home state.
"It's awesome," Brooks said. "It was a thrill to be named a finalist again for this award, knowing whose award it was named for. I'm from Georgia and hopefully we can bring it back to Georgia this year."
Brooks has posted numbers that may make him the favorite, and he's leaving a strong last impression.
Brooks was dominant in Tech's 27-25 win over North Carolina last week. He averaged 60 yards on four punts, including a 77-yarder that was the longest of his career. He also had punts of 63 and 54 yards as he played a big role in Tech's advantage in field position.
"I got to stretch out my leg that game," he said.
The 77-yarder put North Carolina deep in its territory when it appeared it would start at drive on Tech's side of the 50.
Tech had to punt from its 7 early in the second quarter. In those situations, Brooks goes for distance instead of hang time, and his punt sailed far beyond the reach of North Carolina punt returner Brandon Tate, who had to turn his back to Brooks and sprint toward his goal line. The ball bounced to the North Carolina 17.
It was the longest punt in the Atlantic Coast Conference this season, the longest ever for a North Carolina opponent and tied for the seventh-longest in Tech history.
Brooks enjoys unleashing long punts. He's had 11 of at least 60 yards in his two years at Tech after playing two years at Georgia Military College.
But Brooks says he is most proud of his ability to down a ball inside the 20 — especially inside the 5.
On Nov. 11 at Duke, he had punts downed at the 1 and 2. Of his 57 punts this season, 29 have been downed inside the 20.
"I get up the most when I down it inside the 5 and our defense has a chance to stuff them right there," he said.
Men against boys?
Georgia Tech coach Chan Gailey is downplaying a possible matchup advantage for his veteran defensive line. Tech starts seniors Adamm Oliver and Darrell Robertson at the ends and juniors Darryl Richard and Vance Walker at the two tackle spots.
Georgia's offensive line includes three freshmen.
"As of right now they're only two games from being second-year starters," Gailey said of the Georgia freshmen. "They've played a lot of football, and watching the tape from the first of the year to the end of the year, they've gotten a lot better."
Added Gailey: "We won't treat them any different than we treat anybody else. We'll try to keep them off balance just like we do any offensive line."
Tech can be expected to test Georgia's line with its normal blitzes. Tech leads the nation with 42 sacks, including 16 in the last three games.
Three Tech players rank among the top 45 in the nation in tackles for losses: Robertson (14th), Walker (37th) and linebacker Gary Guyton (45th). Tech also leads the nation with hits average of 9.32 tackles for loss per game.
The gambles on defense sometimes lead to big plays, but Tech also is strong against the run, ranking ninth in the nation with its average of 89.5 yards allowed.
Tech vs. Top 25
Tech is looking for its first home win against a top 10 team since beating No. 7 Virginia in 1998.
Tech is 1-2 against Top 25 teams this season, beating No. 13 Clemson and losing to No. 21 Boston College and No. 11 Virginia Tech.
Tech's last win at home against a team ranked as high as No. 6 Georgia was its victory over No. 1 Alabama on Nov. 17, 1962.


text: Puma releases the completely original Fenty Trainer silhouette designed by superstar Rihanna. This model features a premium Ariaprene upper with exaggerated tongue and heel panels for optimal stability. Mesh cage overlays add further support, while the rubber outsole is designed for 360-degree pivots. The Puma x Rihanna Fenty Trainer is offered in White, Black, and Red and is available in-store only at the Kith Manhattan and Kith Women's Store.


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ARTISTIC SUMMARY and ARTISTIC MISSION STATEMENT
My body of work as an artist reflects my ongoing exploration at the border between what's considered art and what's considered purely functional, and my attempt to marry the two in new and unexpected ways. The result is a reinterpretation of traditional forms through unique combinations of utilitarian simplicity and sculptural aesthetics, and unique combinations of different media. In much the same vein, I also find myself driven to combine applications in new ways to create uniquely rich and beautiful effects.
Since I was introduced to sculpture at Bennington College in Vermont, I have continued to develop my artistic skills in a wide range of media, always drawing on my early training in sculpture. I persisted at this pursuit even during and despite a professional career that ranged from motion picture development to web site production. But since 2000, I have dedicated my time and efforts to cultivating a career as a mixed-media artist in which I bring to my works a number of disciplines - including: lapidary, glass, weaving, ceramic and metal smithing.
Goddess Cairn - Ceramic and cement
(Best in Show 2012 - first artist to win two consecutive years in a row, since the show's inception - 58 years ago.)
South Shore Art Center Arts Festival celebrates its 57th year and showcases craft and fine artists from New England and beyond. In addition to almost one hundred juried exhibitor booths, the Arts Festival features a juried art exhibition and members' show, live music performances, artist demonstrations, children's art activities and a young artist exhibition.The Arts Festival draws over 9,000 visitors from the Greater Boston region to historic, oceanside Cohasset Common.
Location: Seaport World Trade Center, 200 Seaport Blvd., Boston, Massachusetts 02210
Teapots and Vessels Displayed in the Copley Place atrium - November, 2011
Work featured in: "American Craft" Published by: The American Craft Council
New Artist Show - Newbury Street Boston
Woven Fish Platter - Featured in the lobby of Children's Hospital South.
189 Alden Street / Box 2814 / Duxbury, MA 02331
1st Prize 3D - Duxbury Art Association Winter Juried Show - February, 2011
The teapot - "Butterfly Kisses": Joins the permanent Teapot Collection at Children's Hospital Boston. October, 2010.
The Woven Car was be featured at:
October 7th - 17th, 2010
Crane Arts Building
400 N. American Street
To see more images of the Woven Car, click on the image below or go to the "Installation" page.
garyhigginsphotography.com credit for the Woven Car pictures
Stickes & Stones / Wiley Ceramics Featured at:
Wickwire Fine Art / Folk Art
L'Attitude Gallery - Boston, MA
211 Newbury St, Boston, MA 02116
Hingham shipyard
Hingham, MA
Commission and custom work available.
Communicate with us at:
or call:
(781) 749-6652
Copyright 2009 Sticks & Stones Ceramic and Woven Works by Jeanne Wiley. All rights reserved.


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Dec 11,2010
And Even More 'Upstairs Downstairs' Related Scans
Posted by Anna with No Comments
Another addition to the residents upstairs is Lady Persephone, played by Claire Foy, 26, best known for playing the title role in 2008's Little Dorrit.
"I am the rebel in this," says Claire, delightedly. "Persie is Agnes's sister, but she's spent her childhood in the Welsh countryside. Agnes brings her to London to do the whole debutante thing but she's uncouth and does the wrong things."
– Scans: Daily Express Saturday (UK) – December 11, 2010
– Scans: TV Easy (UK) – December 18-31, 2010
Big thanks to Lorna for the scans! 🙂
Follow us on Twitter: http://twitter.com/ClaireFoySource
This entry was posted on Saturday, December 11th, 2010 at 4:37 pm and is filed under "Upstairs, Downstairs", Articles, Gallery. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.


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Featured V.I.B. List
In the pre-Mr B's era Portugal, and particularly the gorgeous marble and cork-tree laden Alentejo region, was Mr B and Mrs B's favourite holiday spot....hence our soft spot for its inventive often magical literature
Most recent V.I.B. ListsMr B's Summer Catalogue Mr. B's Christmas Catalogue 2016 Head of Zeus Peirene Press - Possibly Perfect? Book Who's Talking...Caroline Criado-Perez
Other V.I.B. Lists+ Mr B's Top Sellers + Themed Lists: Mainly Fiction + Themed Lists: Mainly Non-Fiction + Themed Lists: Younger Readers + Mr B's Introduction to... Lists - Around the World in Reading Lists
Around the World in 10 Short Story Collections Australia The Czech Republic Germany Hungary Morocco New York City (The Novels) Portugal Spain The Far North Tibet+ Book Lovers Unite! Event Lists + Book Group and Guest Lists + Mr B's Christmas Catalogue List + Books up for Awards!


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Marvel Super Heroes to Join Disney Infinity This Fall
Posted on May 7, 2014
Disney Interactive and Marvel Entertainment have announced plans to make Marvel super heroes available for Disney Infinity. Disney Interactive launched Disney Infinity last year. It features character figures that come to life in the virtual Toy Box universe. It launched with characters from The Incredibles, Monsters University and Pirates of the Caribbean. It was expected at the time that Disney would eventually add Marvel and possible Star Wars characters. Now Marvel superheroes have been added to the line of interactive gaming toys.
Disney Infinity: Marvel Super Heroes will arrive in stores this fall. The collection will feature 20 interactive figures. It will also include original storylines by Marvel comic writer Brian Michael Bendis. Iron Man, Black Widow, Thor, Captain America, Hulk and Hawkeye are six of the characters that have been announced. The remaining characters will be named in the coming months.
The 2.0 edition of Disney Infinity will be available for the PS4, PS3, Xbox One, Xbox 360, Wii U, PC as well as iOS and Android devices. It will be backwards compatible with the Disney Infinity characters sold from the first set.
Jimmy Pitaro, President of Disney Interactive, says in the announcement, "Disney Infinity' was, from the start, built to be an interactive experience where players could bring together their favorite Disney characters and stories to create new Disney memories. With the introduction of 'Disney Infinity: Marvel Super Heroes,' we're ushering in a new chapter of adventures, featuring a cast of the world's most popular super heroes. Bringing popular and iconic Marvel characters to the Disney Infinity platform truly takes this game to the next level."
Take a look:
Photos: Disney/Marvel
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For Oct MSC Bonus sketch week 3
I'm not sure I am liking the white letters on the beige cs so I think I will ink behind them - one day soon....lol
This was the 4th year in a row the Immaculate Conception High School girls tennis team brought home the trophy. Go Meg!
$5.00 $4.00
$0.90 $0.63


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OK, new topic-fish oil?
A few people said they want a new topic. OK, how many people are taking fish oil? My sister, 10 years younger, said her doctor recommended taking fish oil. Omega-3 is known to have health benefits. A nephew adds flax seed oil to his regimen. My problem is the size of the capsules. So I looked on line and found a liquid that I could spoon out and swallow without spasms. It is Barlean's Total Omega and has Omega 3, 6, 9 formulation. It has a pleasant lemon flavor and I take the recommended tablespoon daily. I started about 6 months ago and swear that my knee joints are more flexible. The other benefits are cholesterol and blood pressure reduction. I have read that people on a high statin medication should check with their doctor. I buy mine at drugstore.com.


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For the level 3 ability, wouldn't it be better (flavor-wise) to gain immunity to all diseases? Perhaps toxins too...but I think cockroaches can be poisoned? --Be well 18:53, March 29, 2010 (UTC)
About the level 7 ability, you might want to specify that it refers to any sort of atmospheric pressure. As it is, it can be taken to mean an immunity to bludgeoning damage. --Be well 18:58, March 29, 2010 (UTC)
- Well, the hivemaster already gets immunity to diseases and poisons, so, no real worries there. Trying to keep this feat non-repeatative with the original work. Also, you are probably right on the level 7 benefit. I hadn't thought about having left that open (Well, I did give them DR to everything but bludgeoning damage, but that's a different thing). --Mock Turtle 00:38, April 1, 2010 (UTC)


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Below is our comprehensive list of golf courses in the Riley, Michigan area. We list them by proximity to
Riley, including courses in neighboring cities. Award-winning golf courses are noted. Click on the course name to view more information on the course, including reviews and tournaments. For more golf courses in this region of Michigan, choose a city from the list to the right. For
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Congressional Investigation on the link between Autism and Vaccination On April 6, 2000 Republican Dan Burton convened a congressional hearing regarding the increasing scientific evidence linking vaccination to the increasing dramatic rise in Autism in this country.
Some Excerpts:
Mary Megson, MD explained that autistic children have a total deficiency of Vitamin A as early on as 15 months of age. Her research shows it is directly related to the MMR (Measles, Mumps, Rubella) vaccine. Also in her research she found the Pertussis toxoid found in the DPT shot disrupted certain proteins needed for retinal formation. This finding accounts for the prevalence of night blindness and loss of 3 dimensional vision in autistic children.
John O'Leary, Ph.D. in molecular biology found measles virus in the gut of 96% of autistic children compared to 6.6% of normal children. Dr. O'Leary reports that the virus did not come from natural sources it came from the MMR vaccine. He also stated finding the measles virus in 75% of children with Crohn's Disease.
V. Singh, MD studied over 400 cases of autism and found that these children experienced an autoimmune episode, in which their bodies where made to attack their own nervous system. He stated that 55% of the families stated that the autism appeared after the MMR vaccine and 33% stated autism appeared after the DPT vaccine was administered.
Andrew Wakefield, MD noted an almost 100% incidence of Lymphoid Nodular Hyperplasia or swollen lumps throughout the intestinal system of autistic children. The condition typically follows soon after the MMR shot is administered. He also found that the intestine of newborns cannot function properly because of this swollen condition thus allowing undigested toxins to be stored in the liver.
Kathy Pratt, Ph.D.. stated that ONE in FOUR HUNDRED children in Indiana are autistic! She stated that autism is now more common than Down's Syndrome.
News Channel 5 reports hundreds of thousands of children receive the MMR vaccine every year, but now studies show a tiny percentage of cases may cause autism. Since the MMR vaccine was introduced about 35 years ago,the incidents of autism in children have increased by 1,000 percent - from two or three in 10,000 - to one in 500.
Evidence of a possible link between the MMR vaccination and autism came from the finding of children from villages, within two miles of each other in Scotland, being diagnosed with autism after MMR inoculation.1 The three children from different families in Ayrshire were given MMR vaccine at the same health center within four months of each other. Child neuro-psychologist, Ken Aitken, said that the cluster of cases in Ayrshire indicated the need for further research before the MMR vaccine can be declared safe beyond doubt.
"More children are being diagnosed with autism and clusters like these are deeply worrying", he said. "There is strong circumstantial evidence to point to the MMR as the reason, but there has to be much more coordinated research to look into this issue in detail. Research so far hasn't been adequate to address the questions that are being raised about the possible links and there have been a lot of queries about the validity of the conclusions which were drawn."
In the 1980s, one in 2500 children in Britain and America were diagnosed as autistic. Latest figures compiled by researchers revealed a dramatic leap - to one in 146.
The MMR immunisation was introduced in the UK in 1988 with the first dose aimed at children of 12-15 months, a the second dose at 3-5 years. It is designed to protect against measles, mumps and rubella (German Measles) and works by stimulating the immune system to produce antibodies against the viruses without causing harm. It was so well received by both parents and doctors that over 90 per cent of children were being immunised by 1992.
Most children received the vaccine with no obvious serious side-effects, but some became seriously ill within a few weeks. These children began behaving strangely, stopped talking and became socially withdrawn, staring into space for hours on end. Many developed a raging thirst, bizarre eating habits, multiple food allergies, hyperactivity and sleep problems. This was usually accompanied by abdominal pain, bloating and bowel disturbances. Some children became incontinent of urine or feces. Their development deteriorated. Thousands of children now fall into this category of abnormal development only after receiving the vaccine.
Professor John O'Leary, Director of Pathology at the Coombe Women's Hospital in Dublin, told the US Congress in April, 2000, that he had produced compelling evidence of an association between autism and the MMR vaccine. Professor O'Leary found the measles virus in the guts of 24 out of 25 children who had developed autism, after an apparently previously healthy infancy.
His research supported the findings of Andrew Wakefield, of the Royal Free Hospital, London, who claimed there was an etiological implication between persistent measles virus infection or measles vaccination and inflammatory bowel disease (IBD), mainly on the basis of epidemiological and immunohistochemical findings. Dr. Wakefield identified "autistic enterocolitis", an inflammation of the gut in 150 autistic children who became autistic after receiving the vaccine.
Dr. Aitken, based at Edinburgh University, said, "The substantial increase in cases in the US began about three years after MMR vaccine was introduced and the same thing happened three years after MMR was introduced in Britain. There has been a national increase throughout Britain and I find it very surprising that the change is so tightly linked in time with when triple vaccine was introduced."
On February 28, 1998, Wakefield reported in The Lancet a possible connection among inflammatory bowel disease, autism, and viral infection associated with measles, mumps, and rubella (MMR) vaccination. The damage from autism is thought to be provoked by an allergic reaction initiated by the body's reaction to the vaccine. This auto-immune response may also reduce levels of the dipeptidyl peptidase (DPP)-IV enzyme, thereby connecting vaccines to the opioid theory of autism.
Andrew Wakefield did his first colonoscopy on an autistic child, because the anguished mother begged him to find the reason why her son had such terrible gastrointestinal problems. Finding some very specific pathology, Dr. Wakefield proceeded to investigate 11 more autistic children, again finding similar pathology in all children. These children had lost acquired skills, including communication, after a period of apparent normality.
Among eight of the children, the onset of behavioral problems had been linked, either by the parents or the child's physician, with MMR vaccination Five had an early adverse reaction to immunization (rash, fever, delirium, and seizures in 3). The average interval from exposure to first behavioral symptom was 6.3 days (range: 1-14 days).
Among the remaining 4 children, one received monovalent measles vaccine at 15 months, after which his development slowed. A striking deterioration then occurred in his behavior at age 4.5 years, the day after he received an MMR vaccine. A second child received the MMR vaccine at 16 months, developing at 18 months a combination of recurrent, antibiotic resistant, otitis media, along with his first behavioral symptoms (lack of interest in siblings and lack of play). A third child received an MMR at 15 months, experienced recurrent "viral pneumonia" for the next 8 weeks, and developed behavioral symptoms 4 weeks after the MMR ( loss of speech development and deterioration in language skills). The fourth child developed self- injurious behavior 2 month after the MMR.
Urinary methylmalonic acid excretion was significantly raised in all children tested (8 of the 12). Ten of the twelve children showed lymphoid nodular hyperplasia of the terminal ileum on endoscopy. The eleventh child had prominent luteal lymph nodes and the ileum was not reached in the twelfth (who had an ulcer in the rectum along with chronic colitis).
Wakefield, concluded that a subset of autistic people may suffer brain inflammation resulting from infections that began in their intestines after they were inoculated with the measles-mumps-rubella (MMR) vaccine. Theoretically, this condition could occur after naturally-acquired infection as well. The pro-vaccine community would argue, if this is true, that vaccination still reduces the incidence of disease by reducing the number of infections.
Wakefield's studies received enormous press attention in the United Kingdom. The immediate result of Dr.Wakefield's paper was a vitriolic attack from every front. A flood of opposing articles appeared in the same issue of The Lancet, and systematic criticism, nearing persecution, of Dr. Wakefield began, and is still going on. Rates of vaccination against measles fell to about 85 percent last year. Epidemiologists have been predicting a measles epidemic to result. Ireland reported an outbreak of 300 measles cases as of summer, 2000, compared to only 30for all of 1999. Two of the new cases were infants who had to be hospitalized with pneumonia complications.
Distraught parents of affected children have become even more confused, because no one has been able to prove conclusively to them yet, that an MMR vaccine-Autism connection does not really exist.
We know from data reported before the availability of MMR vaccine, that a subset of autistic children suddenly regressed at age 15 months, long before the measles vaccine became available.There have been no safety follow-up studies looking beyond four weeks post vaccination, and many studies quoted, have been partially funded by vaccine manufacturers, with obvious commercial interests.
No serious researcher has looked at a large sample - three to nine months post MMR vaccination, when auto-immune diseases usually would occur. When some parents in England became vocal, the pro-vaccine authorities in the UK reacted forcefully, to protect the MMR vaccination program. The single measles, mumps and rubella vaccines effectively became unavailable, and every effort was made to prove Dr. Wakefield wrong.
Despite the above, Britain's National Health Service's Chief Medical Officer, Sir Kenneth Calman, felt confident enough to say, "I have concluded there is no link between MMR immunisation and autism." Questioned in Parliament in 1997 on the possible link between MMR and autism, then health minister Tessa Jowell reassured Parliament that: "No vaccine is issued in the United Kingdom unless it passes the highest standards for quality, and parents should have confidence that the vaccines that are provided are both safe and efficacious."
In 1999, two studies appeared that the Department of Health claimed "reinforce the conclusion that there is no link" between MMR and autism. The first, by the Committee on the Safety of Medicines, involved examining questionnaires sent to the parents who had suspected MMR as a cause for their child's autism - 1200 questionnaires were distributed and 126 examined in detail. The study concluded: "It is impossible to prove or refute the suggested associations between MMR vaccine and autism" - hardly convincing reassurance.
The second study cited by the DOH looked at one area - north London - and found an alarming increase in autism there. The incidence was running steadily at between four and eight of the children born there each year between 1978 and 1985. Then came a dramatic increase to just under 50 of the children born in 1992 - the last year studied by Professor Brent Taylor and colleagues at University College London. Curiously, however, they concluded: "Our analyses do not support a causal association between MMR vaccine and autism."
The Taylor study was funded by The Medicines Control Agency and The Public Health Laboratory Service and was published in The Lancet, June 1999. Taylor, et al. stated that the age of diagnosis was the same before and after the introduction of the MMR vaccine, and used this finding to conclude that the MMR vaccine did not have a causative role in autism. Dr. Taylor stated: "For age at first parental concern, no significant temporal clustering was seen for cases of core autism and atypical autism, with the exception of a single interval within six months of MMR vaccine associated with a peak in reported age of parental concern at 18 months." Taylor, et al. Could not explain the increase in autism noted in 1992, the last year for which they examined data.
To others, Taylor's failure to explain the massive increase in autism only added fuel to the controversy. Children who were born in the mid-1980s in Britain and the 1970s in the United Sates were the first to receive the MMR vaccine. In California the incidence of autism was running at 150-200 a year until 1980, when it dramatically rose to reach nearly 600 in 1990.
While Taylor argued that MMR cannot contribute to autism, and Wakefield argued that it might, both studies may be correct. What Taylor may have missed is the susceptible child argument. He limits himself to the more typical, reductionistic, one variable theory of disease. In this theory, one agent causes a disease. All individuals exposed to this agent have equal probability of developing the disease.
A more accurate theory of disease posits susceptible individuals who succumb to the disease after multiple contributory insults. Wakefield worked backwards from children who definitely had autism with gastrointestinal symptoms. Taylor worked forward from all children receiving the MMR vaccine. While various authors question his sampling effort and point out potential bias in how he selected his subjects, the much more important problem lies in Taylor's type of study posing no help for the question of whether susceptible children could be more likely to develop autism after MMR vaccine.
We have only begun to speculate about who is susceptible to autism. We know the risk is higher if one or more family members have the condition. But what are the promoting agents that make autism more likely? Not all children with autistic siblings develop autism. The genetic penetration is not 100%. Non-genetic factors must play a role. Could vaccines be one of these promoting agents? Wakefield suggested yes, and Taylor's study did not really address that question.
Some other investigators have not been able to reproduce Wakefield's findings [M.A. Azfal and colleagues]. They could not detect measles viruses in the bowel, brain, or any other tissue of the patients in Wakefield's series.2
Subjectively, we cannot deny that many parents report developmental deterioration following MMR vaccination. Neurological sequelae following MMR are also widely reported. Dozens of heart-rending, anecdotal accounts link permanent neurologic disability or death to vaccine use. One of the leading sites in the anti-immunization field is the National Vaccine Information Centre (NVIC).
Other studies besides Wakefield's have suggested a link between autism and vaccination. H.H.Fudenberg reported that the first symptoms of autism among 15 of 20 children developed within a week of vaccination. S.Gupta commented on the striking association between MMR vaccination and the onset of behavioral symptoms in all the children he investigated for regressive autism.
The MMR vaccine is all live virus. Disintegrative psychosis is recognized as a sequela of measles encephalitis. Viral encephalitis can give rise to autistic disorders, particularly when it occur early in life.
A genetic association for autism is represented by a null allele of the complement C4B gene located in the class III region of the major histocompatibility complex. The C4B-gene is also crucial for protection against viruses. Affected individuals may not handle certain viruses appropriately - even the attenuated ones used in vaccines. In an addendum to the paper, Wakefield, et al. noted that their sample size had increased to 40 children by Jan 28,1998, with 39 of those showing similar findings. The C4b null allele is present on chromosome 6.3
These studies support our view that MMR vaccine may trigger a cascade of events leading to autism in genetically susceptible children, and not affect children who lack susceptibility. Unfortunately, vaccination among public health and medical practitioners has become almost sacred. Questioning the wisdom of vaccination for certain children is seen as professional heresy. Nevertheless, the possibility cannot be ignored.
Could killed (rather than live virus) MMR accomplish the same task? Should measles be administered separately from mumps? We know that the combination of chicken pox and measles dramatically increases the risk for subacute sclerosing panencephalitis. Perhaps other mixed viral infections are also clinically significant.
More important is the science we must use to explore this. Simple correlation analysis and comparison studies will not suffice. If autism is indeed linked to the MMR vaccine in genetically susceptible individuals, unless these individuals are selected from the larger pool, the statistical significance will cancel out in these studies.
Medical research also suffers from a failure to consider interactions and synergy in the disease process. Simple epidemiology will not suffice either, since we are not even sure what the potential genetic defect is in autism - or if autism is one syndrome or many.
The United States' Center for Disease Control (CDC) believes that the current scientific evidence does not support the hypothesis that MMR, or any combination of vaccines, cause the development of autism, including regressive forms of autism.4 CDC argues that the apparent link between MMR and autism is purely coincidental, based upon the fact that the MMR vaccine is usually given between the ages of 12 and 18 months, which is also the most common age at which autism is diagnosed. One could say, "go figure!", or pursue more sophisticated studies.
An extensive study of the evidence was recently conducted in the United Kingdom. The British Committee on Safety of Medicines convened a "Working Party on MMR Vaccine" to conduct a systematic review of reports of autism, gastrointestinal disease, and similar disorders after receipt of MMR or measles/rubella vaccine. The National Childhood Encephalopathy Study (NCES) was examined to see if there was any link between measles vaccine and neurological events.
The CDC noted that no researchers in England had found any indication that measles vaccine contributed to the development of long-term neurological damage, including educational and behavioral deficits (Miller et al. 1997). A more recent epidemiological study also found no association between MMR vaccine and autism (Taylor et al. 1999). This study compared rates of autism between children who received the MMR vaccine and children who did not. The results found no difference in rates of autism between the two groups. On the other hand, such large scale population studies, would not necessarily be expected to identify a small difference in autistic rates, which, as parents argue, is crucial to those affected.
The CDC agreed with an expert committee from the UK Medical Research Council (MRC) who reviewed Wakefield's research and concluded that no link had been demonstrated between MMR vaccine and inflammatory bowel disease in autism.
Wakefield's study was criticized for:
Using too few cases to make any generalizations about the causes of autism; only 12 children were included in the study. The cases were selected by researchers and may not be representative of many cases of autism.
There were inadequate groups of control children. As a result, it is difficult to determine whether the bowel changes were similar to changes in normal children, or to determine if the rate of vaccination in autistic children was higher than in the general population.
The study did not identify the time period during which the cases were identified. In at least 4 of the 12 cases, behavioral problems appeared before the onset of symptoms of bowel disease; that is, the effect preceded the proposed cause. It is thus proposed unlikely, therefore, that bowel disease or the MMR vaccine triggered the autism. The CDC argues against any scientific research or data indicating benefit to separating the MMR vaccine into its individual components. CDC argued that splitting the MMR vaccine into three separate doses could be harmful because it would expose children unnecessarily to potentially serious diseases. If the rubella vaccine were delayed, 4 million children would be susceptible to rubella for an additional six to 12 months. This would potentially allow otherwise preventable cases of congenital rubella syndrome (CRS) to occur. Infection of pregnant woman with "wild" rubella virus is one of the few known causes of autism. Thus, by preventing infection of pregnant women, rubella vaccine also prevents autism, asserts CDC.
CDC argues that, due to the general safety of vaccines, and the rarity of serious vaccine adverse events [Ed: although, see information from the US government contained in a Database of Vaccine Injury: The Vaccine Adverse Event Reporting System (VAERS)], it is extremely difficult to study whether a subgroup (e.g., family members) are actually at increased risk compared with the general population.
The one exception, they acknowledge, is an increased risk of neurologic events -primarily febrile seizures - after vaccination with DTP vaccine and measles-containing vaccines (MCV). The risk increases if any of these have previously occurred in immediate family members. Considering the rare occurrence of these events after DTP and MCV vaccination, the generally benign outcome of febrile convulsions, and the risk of pertussis and measles to unvaccinated people and the general population, the Advisory Committee on Immunization Practices concluded that a history of convulsions in siblings or parents should not be a contraindication to pertussis or measles vaccination.
Special care in the prevention of post-vaccination fever could be warranted in children with a family history of seizures, they admit. For instance, oral polio vaccine (OPV) is contraindicated when there is a family member with immune-deficiency, since OPV can spread to family contacts.
CDC argues for evidence of the benefits of childhood immunization, including record, or near record, low rates of vaccine preventable diseases in the United States. Last year, for example, there were fewer than 100 reported cases of measles - and no deaths - in the US, compared with 27,786 cases and 64 deaths in 1990.
Kawashima, et al.5 reported that measles virus could be present in the intestines of patients with Crohn's disease. Responding to Wakefield's data on "autistic enterocolitis (see above), the authors set out to determine if the virus found in Crohn's disease, ulcerative colitis, and autistic enterocolitis came from wild strains of measles or from vaccine strains.
To do this, they found measles RNA from peripheral blood mononuclear leukocytes (PBML) in eight patients with Crohn's disease, three patients with ulcerative colitis, and nine children with autistic enterocolitis. They used healthy children and patients with subacute sclerosing pan-encephalitis and human immunodeficiency virus 1 as controls (eight patients).
RNA was purified from PBML, followed by reverse transcription. The resulting cDNAs were subjected to nested PCR for detection of specific regions of the hemaglutinin (H) and fusion (F) gene regions. Positive samples were sequenced directly, in nucleotides 8393-8676 (H region) or 5325-5465 (from noncoding F to coding F region).
One of eight patients with Crohn disease, one of three patients with ulcerative colitis, and three of nine children with autism, were positive. Controls were all negative. The sequences obtained from the patients with Crohn's disease shared the characteristics with wild-strain virus. The sequences obtained from the patients with ulcerative colitis and children with autism were consistent with being vaccine strains. The results were concordant with the exposure history of the patients. Persistence of measles virus was confirmed in PBML in some patients with chronic intestinal inflammation.
Elevated levels of measles antibodies in children with autism.
Singh VK, Jensen RL.
Department of Biology and Biotechnology Center, Utah State University, Logan, Utah, USA.
Virus-induced autoimmunity may play a causal role in autism. To examine the etiologic link of viruses in this brain disorder, we conducted a serologic study of measles virus, mumps virus, and rubella virus. Viral antibodies were measured by enzyme-linked immunosorbent assay in the serum of autistic children, normal children, and siblings of autistic children. The level of measles antibody, but not mumps or rubella antibodies, was significantly higher in autistic children as compared with normal children (P = 0.003) or siblings of autistic children (P <or= 0.0001). Furthermore, immunoblotting of measles vaccine virus revealed that the antibody was directed against a protein of approximately 74 kd molecular weight. The antibody to this antigen was found in 83% of autistic children but not in normal children or siblings of autistic children. Thus autistic children have a hyperimmune response to measles virus, which in the absence of a wild type of measles infection might be a sign of an abnormal immune reaction to the vaccine strain or virus reactivation.
PMID: 12849883 [PubMed - indexed for MEDLINE]
From: TAAP <firstname.lastname@example.com>
Subject: Medical Facts, Not Politics
Medical Facts, Not Politics
While the debate goes on concerning what Dr. Evan Harris did not mention about the Glaxo Wellcome Fellowship, it is important to comment on what he did say about the investigations by the Wakefield group at the Royal Free (1).
Without talking to parents, Dr. Harris suggested that facts had been misrepresented and that the procedures performed on children were not safe, beneficial or even indicated. He also endorsed the statement that research, where there was no likely clinical benefit to children, should not involve anything worse than a blood test.
As a pediatrician with 34 years of practice and the grandfather of a boy who was investigated at the Royal Free Unit in June of 1999, I can assure Dr. Harris and everyone, that the benefits were well worth the small risk we took and of which we were fully informed. We begged to have our boy included in the Wakefield study and patiently waited for nine months for our turn. When his diagnosis was confirmed, we placed him on a liquid formula for 2 months, progressed him to a gluten-free/casein-free diet and started him on the appropriate medications with prompt and sustained improvement of his gastro-intestinal findings, his speech, his social competence and his immune system. Our targeted therapy was selected and proved successful only because we knew the specific pathology he had.
We never felt the investigations were aggressive and we are grateful to this day, for having been included. We believe that the only aggression inflicted on our boy was from the virus that ruined his life, and ours, forever. My grandson has evidence of measles genomic RNA in his gut wall.
Hundreds of endoscopies and colonoscopies are performed on children in order to pinpoint the diagnosis and to formulate the right therapies. A spinal tap in experienced hands is an easy and safe procedure. Much more aggressive investigations are actually performed on infants and children every day and it is safe to state that if the Royal Free program is reinstated, families will be lining up until Hampstead Park.
Dr. Harris is evidently dedicated to the health and welfare of his constituents and of the population at large. There is no doubt that he would be thoroughly distressed if 1 in 100 children died or developed obscure illnesses. Unfortunately, he has not appreciated that a whole generation is being lost and that regressive autism may actually be worse than death, for the children, their families, the communities and the Country. Dr. Harris should realize that sometime, somewhere, he must find the huge funds that are needed for the care that these poor individuals will require for the rest of their lives.
Our children are not simply "autistic" and they do not suffer from a hopeless psychiatric genetic illness that is effectively an Act of God. They have Regressive Autism, a multi-system disease with intestinal, neurological, endocrine and immune manifestations that is precipitated, in all probability, by environmental causes. It is only when that distinction is finally made, that the real causes of this epidemic will be adequately investigated; it is only then that the therapies and educational modalities necessary to limit the damage and improve the prognosis, will be supported.
"Vaccinology" has existed for two centuries; Immunology is a very recent science. Now that more is known about immune disorders and vaccine damage, we should candidly find out where we went wrong.
Maybe indeed, 1+1+1 does not equal 3, when it comes to live viruses and small children?
Maybe in fact, Andrew. Wakefield is right?
Maybe we should look for the truth instead of shooting the messenger?
Reference 1. Ferriman, A. MP raises new allegations against Andrew Wakefield. BMJ 2004; 329:726
Competing interests: Grandfather of a boy with regressive autism
Doctor-Mom Warns of Depakote Use for Treatment of Epilepsy
My nearly 9 year old with post-MMR regressive autism has chronic progressive complex partial epilepsy which has been treated with Depakote since 2/02. It was never discontinued despite lack of efficacy. Despite additional drugs and IVIG, the epilepsy was progressive. Finally he underwent epilepsy surgery last July and we breathed a sigh of relief: 85% improvement with clinical improvements as well.
Because we were not able to completely relieve the epilepsy, however, the anticonvulsants (Depakote and Keppra) were continued. Six months later, the epilepsy is back.... I just came across this correspondence and felt sick. Adam has measles virus F gene in his CSF--significant counts. We took a trip to the ER 41 days after the MMR for high fever and combativeness (very out of character) with no real 'explanation' clinically. He has autistic enterocolitis. So, although I have been assured by 'experts' that it must be a 'false positive' or 'just genetic material hanging around' (5 1/2 years after the one and only MMR?), it's real and I am sure alive and well--especially since it is very likely we have been 'feeding' it with a first-line, inexpensive anticonvulsant: Depakote. In vitro, Depakote increases replication of measles virus. It also increases CMV and HIV. I wouldn't be surprised if it increases replication of other viruses. We simply don't know.
I do not think our kids have SSPE, but I do think some of the kids with autism have measles living and replicating in their little bodies. There are many options for AEDs available. As an organic acid, valproic acid may be more likely to increase viral replication than the newer anticonvulsants. Please post this correspondence and alert parents of children with epilepsy (especially complex partial epilepsy) and gut disease who think the MMR was the 'bullet' for their child. Even if their neurologist doesn't want to believe any of this, he or she may be uncomfortable prescribing an anticonvulsant that supports measles replication. Thanks. Correspondence below.
Debbie Darnley, M.D.
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Transferring Medical Device Production to a Contract Manufacturer - Decision Making Process and Procedures
Product ID: 702719
Training Level: Intermediate to Advanced
- Duration: 90 Min
Customer Care
Fax: +1-650-565-8542
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This webinar on outsourcing medical device manufacturing will discuss practical decision making steps you can follow to analyze whether to transfer or invest in keeping production in-house. If you decide to transfer production, then this training will detail the options and next steps to transferring it to the right facility or contract manufacturer.
Why Should You Attend:
With the economy, many medical OEMs are deciding whether to invest in upgrading equipment, technology, new personnel, transfer it to a lower cost in-house facility or transfer it to a contract manufacturer. In many cases this could save the OEM from investing in costly bricks and mortar, new technology and higher labor cost. It also frees up floor space for new product initiatives.
This 90-minute webinar will give you the steps to follow in making decisions that could save money, time and people. We will explore the importance of quality, cost and on time delivery/flexibility in making the right decisions. This session will also benefit contract manufacturers, since they have to be ready for a seamless transfer of production by understanding their responsibility and the requirements for a medical device transfer, including the transfer process, validations and the pitfalls that could lead to delays.
Areas Covered in the Seminar:
- Gap Analysis, Due-diligence and Decision Making.
- Choosing A Contract Manufacturer.
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This webinar will provide valuable assistance and give a procedure to the medical device companies that are thinking of transferring production to a contract Manufacturer or transferring it to another facility. The personnel who will benefit include:
At Medical Device OEM's:
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Mr. Braido, has 40 years of experience in the medical industry. He is the founder and president of Visionary Consulting LLC and has 40 years of medical OEM's and CMOs to the medical industry. A consulting firm that specializes in gap analysis and due diligence for management evaluation of product transfers, acquisitions and emerging technologies.
Mr. Braido's has a broad breadth of medical industry experience in, product development, global strategic/tactical planning, technical due-diligence/gap analysis for acquisitions, engineering, operations and strong leadership skills to help develop new product concepts for business and marketing. He has had great success working at Ethicon Endo-Surgery a J&J Company, Baxter Healthcare, GW Plastics, Teleflex Medical and The Tech Group with increasing responsibilities to the level of VP of Advanced Technologies. He was a member of the Board of Directors for the SPE (Society of Plastic Engineers) Medical Division for over 10 years and elected Chairman of the Medical Division twice.
Mr. Braido was selected as a member of a Johnson & Johnson Integration Team that took a small fledgling company with totally new products, technologies and structure from $75 million to $850 million in 5 years. His career is built on the ability to motivate, lead and coach people in different disciplines throughout the medical industry. The key factor has been driving innovation.
While working for J&J he was elected, as the Consortium Chairman for the Government Reinvestment Program with MIT, the National Science Foundation and seven leading Fortune 200 companies to commercialize 3D Printing and emerging technologies in metal and plastics. He has also been an independent reviewer for the National Science Foundation, J&J, MIT, EdgeOne Medical, Beeken Medical and others.
He has published numerous technical and leadership articles and white papers. In the past he has shared his extensive experiences at seminars, workshops, technical conferences, symposiums and webinars on subjects relating to the medical industry on due-diligence/gap analysis, product development, product and equipment transfers, leadership and developing an innovation culture for product concept.
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Bringing Compliance To Design Control For Older Products
Bringing Compliance to Design Control through Life Cycle Management of Older Medical Devices and Surgical Instruments
Conformance of Design History Files for Mature Medical Devices
How to Decommission a Medical OEM Molding Operation and Transfer it to a ''World Class'' Medical Contract Manufacturer
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text: The securities litigation firm of Brower Piven, A Professional Corporation, has commenced an investigation into possible breaches of fiduciary duty to current shareholders of Eastern Insurance Holdings, Inc. ("Eastern") (NASDAQ: EIHI) and other violations of state law by the board of directors of Eastern relating to the proposed acquisition of the Company by ProAssurance Corporation. The firm's investigation seeks to determine, among other things, whether the board of directors of Eastern breached their fiduciary duties by failing to maximize shareholder value. According to the press release announcing the proposed acquisition, Eastern shareholders will receive $24.50 for each share of Eastern common stock they own. If you currently own common stock of Eastern and would like to learn more about the investigation being conducted by Brower Piven, you may email or call Brower Piven, who will, without obligation or cost to you, attempt to answer your questions. You may contact Brower Piven by email at email@example.com, by calling (410) 415-6616, or at Brower Piven, A Professional Corporation, 1925 Old Valley Road, Stevenson, Maryland 21153. Attorneys at Brower Piven have combined experience litigating securities and other class action cases of over 60 years.


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On this Friday's FT techtalk, we were joined by Robert Scoble, one of the best known tech bloggers and social media evangelists.
Robert has more than 50,000 subscribers on Friendfeed and 100,000 plus followers on Twitter. He works for Rackspace, is constructing an internet community at Building43 and writes at Scobleizer.com.
We discussed the week's tech news, social media trends and the latest gadgets. There's an archived transcript of the chat after the jump. Read more


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Gunn says Skyler is 'multilayered' and 'morally compromised,' but 'at the end of the day, she hasn't been judged by the same set of standards as Walter.'
Anna Gunn has finally reacted to strong criticisms addressed to her "Breaking Bad" character in the past few years. In an op-ed for the New York Times this weekend, she defended Skyler White, who has been opposing her husband Walter due to his meth business.
In the essay titled "I Have a Character Issue", she said she was aware from the beginning that her character might not be the show's most popular character. "As the one character who consistently opposes Walter and calls him on his lies, Skyler is, in a sense, his antagonist," she admitted.
Gunn, however, "was unprepared for the vitriolic response she inspired" after learning that thousands of fans expressed their hatred through the Facebook page "I Hate Skyler White." The contempt for Skyler has even turned into personal attacks on the actress herself with a post, "Could somebody tell me where I can find Anna Gunn so I can kill her?" as one of the evidence.
In defense of her character, Gunn explained that series creator Vince Gilligan "wanted Skyler to be a woman with a backbone of steel who would stand up to whatever came her way, who wouldn't just collapse in the corner or wring her hands in despair. He and the show's writers made Skyler multilayered and, in her own way, morally compromised."
She added, "But at the end of the day, she hasn't been judged by the same set of standards as Walter." Gunn went on noting that some complex TV wives, namely Carmela Soprano of "The Sopranos" and Betty Draper of "Mad Men", also drew the same negative reactions.
She was concerned that these reactions reflected people's perception of "strong, nonsubmissive, ill-treated" women and wives. "Could it be that they can't stand a woman who won't suffer silently or 'stand by her man'? That they despise her because she won't back down or give up? Or because she is, in fact, Walter's equal?" she asked.
Gunn ultimately blamed it on sexism as she realized that "Skyler didn't conform to a comfortable ideal of the archetypical female, she had become a kind of Rorschach test for society, a measure of our attitudes toward gender."
Gunn's reaction to fans' hatred against her character comes on the heels of "Breaking Bad" final few episodes. The show will return next Sunday, September 1 with a new episode titled "Rabid Dog". In it, "an unusual strategy starts to bear fruit, while plans are set in motion that could change everything."
"Breaking Bad" 5.12 preview:


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Encyclopaedia Britannica
March 28, 2012 by staff
Encyclopaedia Britannica, The man who helped found Wikipedia says the end of the printing of the Encyclopaedia Britannica signals a new beginning for reference materials online.
Jimmy Wales told The Associated Press in an interview Tuesday in Nigeria that resources like the openly edited Wikipedia are the future as they are "accessible to us all the time, not in dusty books on the shelf — no matter how beautiful those might be."
The book form of Encyclopaedia Britannica had been printed for more than 200 years, but it will stop being available when its current stock runs out.
The Chicago-based company that publishes the encyclopedia says it will continue to offer digital versions.Wales was in Nigeria to attend a seminar on youth marketing in Africa's most populous nation.
Please feel free to send if you have any questions regarding this post , you can contact on
Disclaimer: The views expressed on this site are that of the authors and not necessarily that of U.S.S.POST.


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Veterans of ALP national conferences well remember what became known as the holy hand grenade, which John Howard rolled down the stairs at the 2000 event in Hobart.
The then-Labor leader Kim Beazley was having a smooth conference when the Federal Court in Victoria cited federal anti-discrimination laws to overturn a state ban on single women and lesbians using in vitro fertilisation.
Howard wasted no time in announcing his government would legislate to deny the women this right, saying his concern lay with ''the rights of children''.
His move threw the ALP conference into disarray. Beazley said he opposed Howard's decision but, in a bid to keep the focus on the conference, said Labor's response would be decided by the caucus when it next met.
It was futile. The factions went to war, the conference disintegrated and Joe de Bruyn, the national secretary of the ''Shoppies'' - the Shop Distributive and Allied Employees Association - the nation's largest union and aligned with the Catholic Right faction, marshalled his formidable influence.
De Bruyn demanded Beazley sanction a conscience vote, knowing there were enough Labor senators to pass Howard's legislation.
Caucus rejected this, so de Bruyn used his position on the ALP's national executive to call a special meeting to try to overrule Beazley.
The move, if successful, would have had dire consequences for Beazley's leadership. Consequently, it lost by 14 votes to seven, but the episode underscored the power de Bruyn wielded.
At the weekend, de Bruyn had his colours lowered when the Right splintered on gay marriage and largely abandoned him, especially in his battle to stop the party platform being altered to support gay marriage.
The call in advance by Julia Gillard for a conscience vote was a condition imposed by the Shoppies and other bosses in the Right.
Still, had she not made it, enough Right delegates, who were bound by their bosses, would have joined the Left and the conference would have endorsed a compulsory vote. A victory for Gillard of 208 votes to 184 on the conscience vote had to be engineered to prevent embarrassing her.
When it came to endorsing the changes to the platform that commit Labor to amending the Marriage Act to allow same sex-marriage, the drift from the Right was a stampede.
A victory for Gillard on the conscience vote had to be engineered.
Support was so overwhelming that sources said up to 300 of the 400 delegates would have voted for it. It was passed on the voices rather than a show of hands, presumably to spare certain people embarrassment.
The whole gay marriage debate was emblematic in so far as it demonstrated how quickly social attitudes have shifted in the Right. It is generational.
''They know where this is headed and don't want to be accused of being on the wrong side of history in 10 years' time,'' one senior figure said.
At the last conference in mid-2009, gay marriage was thrashed out behind closed doors. The Right was unified in its resistance while the Left fought tooth-and-nail to secure word changes to the platform that barely qualified as semantic.
The grand plan was to advance in increments: secure the word changes in 2009 and then push at this conference for a commitment to civil unions.
That strategy, formulated just two years ago, would have been laughed out of town if put up this time, so quickly have attitudes shifted.
De Bruyn's concerns should not be dismissed. The NSW MP Deb O'Neill, who was more articulate than De Bruyn in arguing against change, warned that those who oppose gay marriage should not be pushed or intimidated.
''Community support is overstated and community opposition is understated,'' she said.
The most recent Herald/Nielsen poll showed 62 per cent of voters supported legalising gay marriage while 31 per cent were opposed.
But not all MPs feel that spread to be even through every electorate, especially those with large ethnic communities.
One NSW MP who supports gay marriage but has a large ethnic community in his seat said he would probably vote against it for this reason.
The policy changes made on Saturday sought to take religion out of the debate by exempting the churches from having to solemnise same-sex marriage. But the churches, backed by the Christian lobby, will still fight.
Gillard is being accused by some as being on the wrong side of history for her stated opposition to same-sex marriage and her advocacy of a conscience vote, which ensures any legislation will not pass this Parliament.
The thousands of pro-gay marriage demonstrators who converged on Darling Harbour after the vote did not applaud the advances made. They chanted ''Shame Labor shame'' because they knew the conscience vote would act as a roadblock for several more years.
Labor delegates looking on cursed that the protesters would still end up voting for the Greens anyway.
''Labor's never got anywhere by being cautious,'' said one.
Follow the National Times on Twitter: @NationalTimesAU


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In March 2009 BNF published a new Briefing Paper on Culinary oils and their health effects.
The paper begins by introducing the worldwide and UK situation of the production, processing and consumption of plant-based oils, including ideal storage of oils. The paper then considers the fatty acid composition of culinary oils and highlights the fatty acids which are associated with specific benefits or risks effecting cardiovascular health. This is followed by current dietary recommendations on fat for cardiovascular health and shows the contribution of culinary oils to nutrient intakes in the UK diet.
The paper then describes the production and processing, nutrient composition and food uses for common culinary oils including rapeseed, sunflower, soybean, palm, olive, peanut, sesame, corn and flaxseed oils and other less common oils such as walnut and coconut oils. It also summarises the evidence for these individual oils and their relationship to health. Comparisons have been made between the fatty acid profiles of the individual culinary oils. In addition, the paper considers plant breeding and modifications to traditional oilseeds and the future developments in plant breeding to favourably modify oil fatty acid profiles to benefit heart health.
Finally, the paper considers culinary oils in a healthy, balanced diet and concludes by highlighting that all oils, regardless of whether they contain 'good' or 'bad' fats, are almost 100% fat and therefore, should only be included in the diet in small amounts.
For more information, the paper is attached below.


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Red Metallic Table SkirtingItem: 014-55048R
Have A Star Spangled Celebration with Patriotic Party Decorations
The party doesn't start until everything is starred and striped. So don't start your Fourth of July party without the perfect patriotic party tableware.
- 1 table skirt per package.
- 30″ tall and 14′ long.
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- Make sure your tableskirt is secure with table clips.
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Show your American pride with must have patriotic party tableware like these. USA decorations are perfect for any Fourth of July party or patriotic theme event.


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Edit Article
wikiHow to Shave Your Legs Using Coconut Oil
Need to shave your legs? Are they getting a little rough? Try using coconut oil.
1Keep a small container of it in the shower. Coconut oil solidifies at fairly moderate temperatures, so a hot shower will soften it and help your skin absorb it.
2Remove most of the water from your legs with a damp washcloth.
3Turn off the shower if you can, or maybe step out of it.
4Coat your legs with a thin layer of the coconut oil. Use about a teaspoon per leg. A little will go a long way.
5Shave your legs.
6Rinse your razor frequently. The oil will clog up the razor.
7Rinse off after finishing.
8Pat your legs dry (as opposed to rubbing them). If you rub your legs, this will get rid of the coconut oil that you used and all of its benefits. The residue will leave your legs well moisturized.
9If you want to, massage in more coconut oil to moisturize your legs even further.
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Doctor insights on:
Fastest Way To Get Rid Of Strep Throat
Please explain how do you get rid of strep throat fast?
Strep throat: Streptococcal throat infection requires antibiotic therapy. Need to complete the full course of it in order to avoid recurrence of the disease or resulting in complications that follows the infection. Avoid spread by avoiding sharing the same utensils/kissing, close contact for at least 24 hours after starting antibiotic therapy. ...Read more
Strep Throat (Definition)
It's a throat infection caused by a strep bacteria that responds rapidly to most antibiotics. There can be a number of other bacteria involved in addition to strep so a regular culture (not just a quick strep ...Read more
Please give advice on how to get rid of strep throat fast?
Two steps: Step one: proper diagnosis= quick strep test with high accuracy step two: take your medicine on schedule you will not be contagous after 24hrs on meds but you need to finish them. Comfort measures including ibuprofen, throat sprays or lossenges can also help. ...Read more
How to get rid of strep throat fast without an antibiotic?
You can't: If you have actually been diagnosed with strep throat (with a test....It can't be accurately diagnosed by looking at it), then it is really important to clear it up with an antibiotic. The bacteria that causes strep throat can cause other problems with your kidneys or heart, and no alternative medicine will prevent those problems from happening. ...Read moreSee 2 more doctor answers
Is there a good way to get rid of strep throat without getting a swab?
It should resolve. : Most strep infections will resolve without any antibiotic treatment. However, you should know what you are risking. Strep antibiodies can damage you own body tissues, especially heart valves. This can cuase rheumatic heart disease and can irreversably damage your heart. This is why we treat step agressivley with antibiotics. Good luck. ...Read moreSee 1 more doctor answer
How to get rid of strep throat without medication?
Playing the odds: You can always play the odds and see what happens.Like the folk in the early 1900s.They also had strep & it passed.However, about 1/200 developed 1of 3 patterns of complications.The brain thing, chorea, put some in mental hospitals.The kidney thing led to sudden kidney failure that some did not survive.The heart thing ate up heart valves and left many weak for the remainder of a short life.Treat it. ...Read more
Can you take Claritin (loratadine) d to get rid of strep throat?
No: Antibiotics are required to kill the bacteria that causes strep throat. Claritin-d might make you feel somewhat better, but it will not treat it. Untreated strep throat has the potential to have long term side effects. ...Read more
How can I get rid of strep throat without going to a doctors office?
How do you know?: There are no specific symptoms of strep throat that distinguish it from other causes of sore throat. A screening test or culture is the only way to be sure it's strep. Most of the time a sore throat will get better by itself. The main reason for treating strep throat is to prevent rare but potentially serious complications, like rheumatic fever which can cause permanent heart damage. ...Read moreSee 1 more doctor answer
Is there anyway to get rid of strep throat without going to a doctor for anitbiotics?
No: Dr. Diamond is right: take no chances. ...Read moreSee 2 more doctor answers
Doctor gave me antibotics, but not for my throat. How can I get rid of strep throat?
Strep throat: Only certain antibiotics help strep throat. The trick is if you really have strep throat or not. If someone doesn't have fever, doesn't have pus on tonsils, doesn't have big swollen lymph nodes, but does have a cough or runny nose, it is very unlikely they have strep throat. A simple in-office strep test can help though, and if positive, you can get the proper antibiotic. Best of luck! ...Read moreSee 1 more doctor answer
How do you get rid of strep throat? I have no insurance so i can't afford to see a doctor. But i've been drinking tea with honey. What type of medicine should I take?
For : For throat pain you can take advil or tylenol (acetaminophen). Continue drinking plenty of fluids. If you have worsening pain, fever, rash or vomiting though you are going to have to be seen. ...Read more
Pharynx (Definition)
It is the connection between the mouth and the throat. The 3 parts are the oropharynx, nasopharynx, and hypo-pharynx. The pharynx leads into the ...Read more
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A 16-year-old has been connected to a bicycle theft on Baker Avenue.
Police released video of the incident Tuesday in hopes of finding the suspect. According to a news release, the teen was taken to Augusta RYDC on Tuesday evening on two counts of burglary and two counts of motor vehicle theft.
Police said some of the charges were related to other incidents.


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League One: Steven Pressley happy to remain at Coventry City
Coventry City manager Steven Pressley insists he has no intention of leaving the League One club.
Last Updated: 07/01/14 4:22pm
The Scot has been linked with the vacant Millwall job but he has reaffirmed his commitment to the Sky Blues ahead of Saturday's FA Cup third round match against Barnsley at Oakwell.
The 40-year-old, who took charge of Coventry on March 8 last year, told his club's official website: "Those reports don't concern me because I will say to you what I have said in the past, I have absolutely no intentions of leaving this football club.
"I'm really, really happy here. I was given the opportunity to manage here and I want to build a future here.
"I am loving my time here and my family have settled into the area really well so I have absolutely no desire to leave.
"I can only stress how happy I am here and I will definitely be at this club for the foreseeable future."


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Johnnyrandom Barcelona, Spain
Johnnyrandom is an American composer specializing in the genre of Musique Concrète: A form of electroacoustic music that is made in part from acousmatic sound. His works strive to promote awareness of one's surroundings by tuning into the intrinsic beauty produced by everyday objects. ... more
Streaming and Download help


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Update: Motte has what the club is describing as a "mild strain" in his right elbow that will keep him off the mound for at least week as the team explores the severity of the injury and potential treatments, the St. Louis Post-Dispatch reports. General manager John Mozeliak said Motte will "likely" start the season on the disabled list with the flexor strain.
Recommendation: Manager Mike Matheny said Mitchell Boggs will get the first opportunity to serve as closer in Motte's absence.


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- {{matchup.date.fullday}}{{matchup.date.month + ' ' + matchup.date.day}}
Southern Conference Tournament - Davidson Defeats Samford 77-54 - Recap
Davidson cruised to victory on Saturday, running Samford out of the gym and running up a 77-54 score at U.S. Cellular Center.
Davidson got 26 points from De'Mon Brooks and another 14 points from Jack Gibbs. Tyler Kalinoski contributed 3 assists, while De'Mon Brooks cleaned the glass with 12 rebounds.
Samford got a 14-point performance from Jordan Capps, who was supported by 7 points from Raijon Kelly. Connor Miller had 5 assists in a losing cause for Samford, while Connor Miller grabbed 8 rebounds.
First-half bettors who backed Davidson were victorious, as the score was 42-26 at the break.
Davidson won the battle of the boards, outrebounding their counterparts 36-35.


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Cowboys' Kitna hopes Romo gets all the work
Published 12:00 am, Friday, August 27, 2010
OXNARD, Calif. — In an iconic 1970s TV commercial, the "Maytag Repairman" bemoans the fact his services aren't needed.
That's something Jon Kitna would never do.
The Dallas Cowboys' Tony Romo was the only quarterback in the NFL to take every snap last season, and his backup said he hopes it happens again.
"I was absolutely content and happy watching Tony have the success he had last year," Kitna said. "It was a great step for him and this team. That's what I want to be a part of — a team that wins. And we have a chance to do that."
While Romo toiled, Kitna recovered from the physical toll of playing the previous three seasons with hapless Detroit. He also immersed himself in the playbook, learning his new team's terminology inside and out.
And he encouraged Romo to get all the work.
"Even when we were leading by 21 and all he had to do was hand off the ball in the last two minutes, I told him take every snap," Kitna said. "I was happy for him he got to do it."
Sports Channel
Kitna knows firsthand the pride that comes from taking every snap. He's done it twice in 13 seasons (2003 with Cincinnati and 2006 with the Lions), according to STATS LLC. Discounting gimmick plays like the wildcat, only nine quarterbacks since 2006 have accomplished the feat.
"It shows your teammates you are committed, especially when you're hurt," Kitna said.
Romo is just glad he's got Kitna as a caddie.
"Jon is a great guy to bounce ideas off of," Romo said. "He's very knowledgeable. He's easy to talk to, and he thinks like me. We've got a lot in common."
Kitna, who turns 38 on Sept. 21, has looked sharp in the preseason. Last weekend in San Diego, he completed 9 of 15 passes for 84 yards with a touchdown — a performance that pleased Jerry Jones.
"I'm going to sleep better about quarterback tonight than I've slept this year, because Kitna was outstanding," Jones said.
Kitna's play, which included a 19-yard scoring strike to Martellus Bennett, also impressed Romo.
"We are lucky to have Jon," Romo said. "He can still play this game at a high level. I feel very comfortable with this team going forward if I were to go down. It's a luxury most teams don't have."
But Kitna would prefer to spend the season watching Romo thrive as he did last year, when he passed for a team-record 4,483 yards and 26 TDs.
"I'm not in it for the excitement," he said. "I'm in it to win."
Dallas acquired Kitna in a trade that sent cornerback Anthony Henry to the Lions. After arriving in Irving, he began working to "build his body back up" after absorbing 129 sacks with the Lions.
Despite the pounding, Kitna stands tall in the pocket.
"There's no flinching where I grew up," the native of Tacoma, Wash., said.
A starter for three franchises, Kitna has passed for 27,293 yards, 152 TDs and 151 interceptions.
Asked whether he plans to play into his 40s, Kitna turned philosophical.
"I came into this league (out of Central Washington) hoping to get one year," he said. "I was an undrafted free agent. ... I had one team (interested). So I wanted to get one year. My wife and I had been married two years and we wanted to get out of debt.
"God has taken my little dream and turned it into something I never would've dreamt, sitting here in Oxnard, Calif., playing for the Dallas Cowboys, going into year 14. So I don't even think much about how long I'm going to play. When the time is done, God will close the door."


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About the Book
A simple 80 photo picture book of the 2008 Head of the Charles Regatta. Photos by Mark Wilson
Features & Details
- Category Sports & Adventure
Small Square, 7×7 in, 18×18 cm
40 Pages
- Publish Date Nov 20, 2008
- Tags head of the charles, rowing, Boston, scull, racing, row, dietz, crew, harvard, northeastern, umass, sports, kayak, row2k
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Another round of nuclear talks between EU and Iran end without agreement
Iran and the European Union troika held another round of nuclear talks in Vienna, Austria, on Friday, news sources said. the talks, however, ended without any agreement, ministers said.
French Foreign Minister Philippe Douste-Blazy said the EU had been demanding "full and complete suspension" of enrichment and related activities. "Unfortunately we were not able to reach an agreement," he told reporters after the meeting.
Before this round of Iran-EU3 talks, Secretary of Iran's Supreme National Security Council (SNSC) Ali Larijani paid a two-day visit to Moscow at the head of a high-ranking delegation and held nuclear talks with Russian officials including Head of Russia's Security Council, Igor Ivanov.
Larijani and Ivanov discussed bilateral nuclear cooperation as well as Moscow's nuclear proposal for Iran on a jointly uranium enrichment project inside Russia's territory, IRNA reported.
The talks between Iran and foreign ministers of the EU troika (Germany, France and Britain) held following a request by Tehran before an upcoming session of the Board of Governors of the International Atomic Energy Agency (IAEA), to be held on March 6.
Larijani, addressing a press conference at Iran's embassy at Moscow on Thursday, said, "We are ready to hold talks with the European states within frameworks of international regulations and the Non-Proliferation Treaty (NPT)."