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A Phase I/II Study of [124I]mIBG PET/CT in Neuroblastoma
This study is currently recruiting participants.
Verified April 2016 by Cancer Research UK
Cancer Research UK
Information provided by (Responsible Party):
Cancer Research UK
ClinicalTrials.gov Identifier:
First received: January 21, 2014
Last updated: April 13, 2016
Last verified: April 2016
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- No Study Results Posted
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- How to Read a Study Record
This study aims to show that 3-dimensional PET/CT imaging with a new novel PET tracer (called [124I]mIBG) can detect as many or more sites of neuroblastoma (a type of childhood cancer) compared to the recommended 1-dimensional routine scans (called [123I]mIBG planar scintigraphy).
|Metastatic Neuroblastoma (Stage 4 on International Neuroblastoma Staging System (INSS))
|Drug: [124I]meta-Iodobenzylguanidine
|Phase 1 Phase 2
|Study Type:
|Study Design:
|Primary Purpose: Treatment
|Official Title:
|A Cancer Research UK Phase I/II Study to Compare [124I]Meta-Iodobenzylguanidine (mIBG) Positron Emission Tomography/Computerised Tomography (PET/CT) to [123I]mIBG Imaging in Patients With Metastatic Neuroblastoma
Resource links provided by NLM:
Genetics Home Reference related topics: neuroblastoma
MedlinePlus related topics: NeuroblastomaU.S. FDA Resources
Further study details as provided by Cancer Research UK:
Primary Outcome Measures:
- Comparison of the percentage of lesions detected as positive by [123I]mIBG planar scintigraphy which are also considered positive with [124I]mIBG PET/CT [ Time Frame: 3-14 days after routine [123I]mIBG ]Imaging data from each imaging modality will be read and scored separately by four expert Nuclear Medicine clinicians following receipt of a complete set of data for each patient.
Secondary Outcome Measures:
- Assessing the safety and toxicity profile of a single intravenous administration of [124I]mIBG [ Time Frame: Consent to Day 3 - 7 ]Determining the causality of each adverse event to [124I]mIBG and grading severity according to National Cancer Institute Common Toxicity Criteria for Adverse Events (NCI CTCAE) version 4.02.
|Estimated Enrollment:
|Study Start Date:
|February 2014
|Estimated Primary Completion Date:
|October 2018 (Final data collection date for primary outcome measure)
Intervention Details:Detailed Description:
Drug: [124I]meta-Iodobenzylguanidine
Single intravenous administration of [124I]mIBG Solution for Injection on Day 1 with a maximum radioactive dose of 1.42 MBq/kg (±10%) and a maximum injected dose of 50 MBq [124I]mIBG equating to a maximum chemical dose of 10 micrograms of stable mIBG. The activity to paediatric patients will be scaled by weight based upon the EANM paediatric dose card (Lassmann et al., 2007). This will result in an activity between 10 MBq and 50 MBq depending on the patient's weight.
Neuroblastoma is the most common tumour of childhood after brain tumours. Approximately half of cases are high risk and despite extensive treatments outcome is very poor. More than 60% of high risk patients suffer relapse or further spread of their disease and long-term survival is below 10%. Existing imaging techniques are not sensitive enough to accurately assess the level of risk which is critical in determining the best choice of treatment. This study will compare a new type of imaging against the existing imaging techniques. The new scans use a new tracer called [124I]mIBG which is taken up by the cancer tissue much more than by normal tissues. This tracer can be used with a 3D imaging technique called PET/CT to pinpoint where the disease has spread and quantify the amount of disease. Patients will be those scheduled to have an [123I]mIBG scan for routine care during a planned break in treatment.
|Ages Eligible for Study:
|1 Year and older (Child, Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Histologically proven Stage 4 neuroblastoma as defined by the International Neuroblastoma Staging System (INSS).
- Aged ≥ 1 year at the time that written informed consent is given.
- Planned to undergo conventional [123I]mIBG planar scintigraphy for routine clinical care of neuroblastoma.
- Life expectancy of at least 12 weeks.
- World Health Organisation (WHO) performance status of 0, 1 or 2 (Appendix 2) for patients aged > 12 years old or Lansky play scale score of ≥ 50% (Appendix 3) for patients aged ≤ 12 years old.
- Written (signed and dated) informed consent from patient ≥ 16 years old and/or parent or legal guardian for patients <16 years old and the patient be capable of co-operating with scanning requirements. (N.B. Written or verbal assent as appropriate should be sought from all patients who are under 16 years old).
Additional Inclusion Criteria for Biokinetic sub-study
- Aged ≤ 16 years at the time that written informed consent is given.
- No requirement for general anaesthesia to undergo PET/CT scanning.
- Written (signed and dated) informed consent for the sub-study from patients aged 16 years or from the patient's parent or guardian for patients aged <16 years. Capable of co-operating with the additional study PET/CT scans. (N.B. Written or verbal assent as appropriate should be sought from all patients who are under 16 years old.)
Additional Inclusion Criteria for PET/MRI sub-study
- No requirement for general anaesthesia to undergo hybrid PET/MRI scanning.
- No previous experience of claustrophobia.
- Written (signed and dated) informed consent for the sub-study from patients aged 16 years or from the patient's parent or guardian for patients aged <16 years. Capable of co-operating with the additional study PET/MRI scans. (N.B. Written or verbal assent as appropriate should be sought from all patients who are under 16 years old.)
Exclusion Criteria:
- Treatment with any medications contra-indicated with mIBG scanning as listed in Appendix 4. For example, decongestants containing pseudoephedrine, phenylpropalomine and phenylephrine, sympathomimetics, cocaine, antihypertensives, tricyclic antidepressants. These drugs should be stopped before administration as indicated in this list (usually for four biological half-lives to allow almost complete wash-out but refer to list).
- Stage 4S neuroblastoma as defined by the INSS.
- Any anti-cancer treatment planned between the routine [123I]mIBG imaging and the [124I]mIBG PET/CT scan on Day 2. Anti-cancer treatments can be started only after the Off-Study assessment on Day 3 to Day 7, see schedule of assessments in Section 7. N.B. Patients should not be enrolled in the study if their participation will delay their subsequent treatment for neuroblastoma.
- Female patients who are pregnant or lactating.
- At high medical risk because of non-malignant systemic disease including active uncontrolled infection.
- Known to be serologically positive for Hepatitis B, Hepatitis C or Human Immunodeficiency Virus (HIV).
- Patients with known hypersensitivity to mIBG.
- Any other condition which in the Investigator's opinion would not make the patient a good candidate for the clinical study.
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT02043899
Please refer to this study by its ClinicalTrials.gov identifier: NCT02043899
|United Kingdom
|University College London Hospital
|London, United Kingdom, NW1 2PG
|Contact: Contact Person firstname.lastname@example.com
|Principal Investigator: Mark Gaze, Dr
|Royal Marsden Hospital
|Sutton, United Kingdom, SM2 5PT
|Contact: Contact Person email@example.com
|Principal Investigator: Sucheta Vaidya, Dr
Sponsors and Collaborators
Cancer Research UK
More Information
Keywords provided by Cancer Research UK:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on August 21, 2017
|Responsible Party:
|Cancer Research UK
|ClinicalTrials.gov Identifier:
|NCT02043899 History of Changes
|Other Study ID Numbers:
|Study First Received:
|January 21, 2014
|Last Updated:
|April 13, 2016
Keywords provided by Cancer Research UK:
Positron emission tomography
Additional relevant MeSH terms:
Neuroectodermal Tumors, Primitive, Peripheral
Neuroectodermal Tumors, Primitive
Neoplasms, Neuroepithelial
Neuroectodermal Tumors
Neoplasms, Germ Cell and Embryonal
Neoplasms by Histologic Type
Neoplasms, Glandular and Epithelial
Neoplasms, Nerve Tissue
Antineoplastic Agents
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
ClinicalTrials.gov processed this record on August 21, 2017


text:
Ringworld by Larry Niven
View Single Post
...still a Zealot
Posts: 268
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Join Date: Feb 2012
Location: Kansas City, Kansas, USA
Device: Palm Pixi & PC
Okay, I'm a big Niven fan....
My favorite thing is that his books always seem to be based on an interesting "hard" science fiction premise, and logically build from there, but still goes into the character aspects, as well.
I love Ringworld. The cultural concepts of the Puppeteers is fascinating, to me. I, too, found some of the later in the series less than compelling.
My favorite Niven books are 2 of the mentioned that he co-wrote with Pournelle-- The Mote in God's Eye (which I consider one of the 10 must-read SF classics), and Lucifer's Hammer. Strangely, I tried reading Pournelle's solo books, convinced that I would find another author I loved, and really didn't like them at all. One of those cases when a collaboration works greater than the sum of it's parts, I guess.
I'll read anything I can run across by Niven, and re-read even my least favorites (well, except for 1, and I won't mention which, because it might be somebody else's cup of tea.)
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text:
Swedes Hardcore Superstar have made their entire new upcoming album "Beg For It" available for streaming online. You can check it at the group's MySpace page. The new Hardcore Superstar album will be released on June 3rd via Nuclear Blast Records.
The album will be streaming till Wednesday.
The album will be streaming till Wednesday.
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Office Machines
Calculators & Counters
Printing Calculators
Sharp Electronics
Item # SHR EL2192RII by Sharp Electronics (Mfg. Part # SHREL2192RII, UPC # 74000016699)
|Receive Betty's Coupons, Special Offers & Promotions!
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Unless you are a licensed care provider or similar
qualified entity, a prescription is required
to purchase this item.
Thanks! -- Betty Mills


text:
The 'Late Night with Jimmy Fallon' host teams up with Fred Armisen to deliver the Christmas song, but they can't figure out the right melody.
Jimmy Fallon is bringing the spirit of Christmas in promos for the next episode of "Saturday Night Live". The 37-year-old comedian appears along with regular cast member Fred Armisen to remind viewers of his impending hosting gig on the variety show.
When Armisen plays a guitar and sings "Jingle Bells", Fallon interrupts him and tries to show the right tune. However, he also twists the melody halfway through the song. In another promo video launched on Facebook, the two even perform the Christmas song with some different versions although still maintain the lyrics.
The "SNL" episode featuring Fallon as the host will air this Saturday, December 17 at 11:30/10:30c on NBC. Michael Buble has been booked as the musical guest.
The upcoming appearance will mark the first time Fallon hosts "SNL" since he left the show in 2004.


text:
Trends In Human Resources Structure
As a result of economic globalization, technological progress and population growth, changes occur in the structure of human resources, in all worlds' economies. This paper presents the trends of human resources structure in the European Union and Euro zone. Using the International Monetary Fund (IMF) predictions on GDP, the paper tries to predict the future trends of human resources structure in the European Union. Following research I found there is an increase in services sector employment at the expense of industry and agriculture employment.
If you experience problems downloading a file, check if you have the proper application to view it first. In case of further problems read the IDEAS help page. Note that these files are not on the IDEAS site. Please be patient as the files may be large.
Volume (Year): XI (2013)
Issue (Month): 2 (November)
Pages: 255-264
|Contact details of provider:
| Postal: Str. A.I. Cuza nr. 13, Craiova
Phone: 004 0251 411317
Fax: 004 0251 411317
Web page: http://feaa.ucv.ro/
More information through EDIRC
References listed on IDEAS
Please report citation or reference errors to , or , if you are the registered author of the cited work, log in to your RePEc Author Service profile, click on "citations" and make appropriate adjustments.:
- Isabelle Huault & V. Perret & S. Charreire-Petit, 2007. "Management," Post-Print halshs-00337676, HAL.
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text:
The Weekender: Summer's just around the corner, celebrate with this week's Weekender
Hey guys! For us Brits in the UK it's actually a Bank Holiday weekend right now, which means we're going to spend the next four days drinking shandies in the sun and being forced by children to hunt for eggs in damp, pansy-ridden back gardens – fun! The Bank Holiday gives everyone in the UK a feeling of magic, a tickle of fire in the belly, a feeling that anything and everything is possible. And maybe it is. Let The Weekender guide you into what could be the best weekend of your life.
Stuff you may have missed this week
– Top Boy and Misfits director Jonathan van Tulleken told us about his top five books this week and also gave us an insight into the working life of a director.
– Camilla Mantovani told us why Jonathan Glazer's video for Radiohead's epic Street Spirit is the best video ever. Can't really argue with that.
– And to celebrate the launch of the new Tom of Finland stamps, Maisie Skidmore ponders about the role of the stamp in design culture.
The Weekender
Liv Siddall -
Came across this poster on Facebook the other day and it blew my mind. I feel a lot of the time, usually when I'm on the Tube, that they just don't make film posters like they used to. Imagine someone being this bold nowadays? Wouldn't happen, the sponsors would go mental. For me, this is perfect. Obviously if you haven't seen Leon then this won't make any sense to you at all. Oops! Silly me, everyone's seen it.
Lisa Farrell -
In the early days of Errol Morris' film-making career he experienced something of a mental block in completing his documentary Gates of Heaven. In a bid to motivate him, his then mentor Werner Herzog promised that he would cook and eat his own shoes if Errol finished the film.
Errol did finish it, and Werner kept his word.
Maisie Skidmore -
My contribution to The Weekender this week is a space mystery involving cherry trees, an astronaut and Buddhist monks from a temple in central Japan. It loosely revolves around the fact that pretend-sounding phenomena like "microgravity" and "cosmic rays" have caused a tree, which was grown from seeds which had previously travelled to space, to grow extraordinarily quickly. I'll let that sink in for a moment.
Why am I sharing this with you? Because you might naively have supposed that you'd never read a news story about a "Space Cherry." I, friends, am here to prove you wrong.
Rob Alderson -
As first sentences go, "Everyone loves a good epithet" renders me powerless to resists an article's charm. And this post on The Social Historian blog gets better from there, focusing on those historical figures who weren't quite as lucky as Richard the Lionheart. From Crazy Otto of Bavaria to Ivaylo the Cabbage there's some terrifically cruel nicknames, but all pale into insignificance next to the magnificently-derided "James The Sh*t."
- Animator Dan Castro tackles the intricacies of relationships in this funny short
- "I don't want to lose my connection with the tangible": illustrator Jack Taylor on his new digital and 3D process
- Greta Thorkels: a graphic designer creating Gilmore Girls zines and record sleeves
- Grégory Michenaud's ongoing project sees him explore identity in a Hasidic Jewish community
- Photographer Gilleam Trapenberg explores macho culture against rose-tinted skies in Big Papi
- From analogue printing to illustration: meet Marc Hennes
- The New York Times Magazine's new cover is actually a painting
- BBC's new typeface BBC Reith is designed to improve legibility on screen
- "It needs to be normalised that women masturbate": meet illustrator Jordyn McGeachin
- Life through the lens of enchanting photographer Vicki King
- Six months in the (enviable) life of photographer Ryan Lowry
- We get to know hilarious and thoughtful illustrator, Ruby Etc


text:
Hong Kong broking firms feel heat from rivalry
One in four brokerages may close as banks enter the securities market and fees plunge
One in four home-grown brokerages may close as trading and fees plunge and competition from banks intensifies, according to an industry group.
The number of local broking firms might fall to 300 from about 400 in the next five years, said Mofiz Chan, a spokesman for the Hong Kong Securities & Futures Professionals Association.
"There are many people taking part-time jobs or completely moving out of the industry," Chan said. "Many of our members have needed to shift into other jobs, such as security, driving a taxi or tutoring primary school students."
Fees have dropped since Hong Kong Exchanges and Clearing (HKEx) removed a brokerage commission floor in 2003 of 0.25 per cent of the value of transactions, squeezing profits for brokers as mainland rivals expanded their operations.
The competition has claimed foreign equity traders, with South Korea's Mirae Asset Securities and Japan's Daiwa Securities among firms that have cut jobs.
Eleven brokerages have ceased trading this year, according to filings posted on the website of the stock exchange. King Fook Securities, established in 1971, said it would close at the end of this month.
Brokers have been hurt after the average value of stocks traded daily plunged to HK$53.7 billion last year from HK$69.5 billion in 2011.
"If there is no improvement in our operating environment, more and more owners of long-established local brokerages will get frustrated and exit the market," said Christopher Cheung, the founder of Christfund Securities and a lawmaker representing the industry.
HKEx should reinstate the broker commission floor, Chan and Cheung said.
The mainland's Big Five banks all offer securities trading services in Hong Kong through their local units. The Chinese Securities Association of Hong Kong, which comprises mainly mainland-backed brokerages in the city, has increased its members to more than 65 from 19 when it was founded in 2009.
Commissions at Bank of China (Hong Kong), the largest Hong Kong-based mainland lender, have dropped as low as 0.18 per cent of the transaction value if trades are done online, according to its website.
HKEx had 511 stock trading members, according to its 2012 annual report. The biggest 65 accounted for 90 per cent of transactions last month, compared with 82 per cent in June 2003.
Technology upgrades needed to link into HKEx's new faster trading platforms were pricing local securities firms out of the market, Chan said.
The introduction of after-hours futures trading hurt local brokers, who said they would lose customers if they could not afford staffing to offer access.
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Cameron Naasz beat his biggest recent rival and nabbed first place in Moscow on Saturday as part of the Ice Cross Downhill World Championship, just two weeks after taking third at Red Bull Crashed Ice in St. Paul.
Naasz, 24, of Lakeville, beat Marco Dallago, 23, from Austria against a backdrop of 18,000 spectators in the downhill skating event on a nearly 1,500-feet-long winding track, according to Red Bull Crashed Ice. Dallago beat Naasz in the St. Paul event on Feb. 22, and also won the first event of the season in Helsinki, Finland.
Latest standings show Dallago is ranked first at 2,800 points, with Naasz trailing 840 points behind in second.
Naasz, who joined the sport two years ago, grew up in Lakeville and graduated from St. Cloud State University in public relations, according to Red Bull Crashed Ice. The organization said he started playing hockey when he was 5 years old. He later played for Junior Gold Hockey, a group for skaters who didn't qualify for their high school teams, and won the 2008 State Championship.
His first Crashed Ice victory was in Lausanne, Switzerland last year, making him the first and only American to win an event. The majority of the event's past winners are from Canada, Finland and Sweden.
Invented as a marketing strategy by Red Bull to promote its nonalcoholic energy drink, the winter extreme sport started in 2001 in Stockholm, Sweden. It has since attracted athletes from around the world to compete in steep downhill tracks dotted with curves, jumps and bumps. Amateur ice skaters and professional ice hockey players can qualify for the races, according to the sport's website.
Apart from 2014 tournaments in St. Paul and Moscow, Red Bull Crashed Ice also hosted one in Helsinki in early February, and will host the finale in Quebec City in Canada on March 20-22.
Results are online at redbullcrashedice.com.
Raya Zimmerman can be reached at 651-228-5524. Follow her at Twitter.com/RayaZimmerman.


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David PriceBA (Hons), PGCE
David Price is Pro-Vice-Chancellor (Strategy & Performance), with responsibility for leading Cardiff Metropolitan University's strategic planning, performance management and associated frameworks. A member of the Vice-Chancellor's Board, David's role also encompasses responsibility for leading cross-cutting initiatives and change programmes, risk management, the University's Fee Plan, and representing the University externally.
Born in Denmark and raised in Sarawak, Fiji and Australia, David completed his school education in Somerset before reading History at the University of Sheffield. After completing a PGCE at the University of Newcastle-upon-Tyne, he taught at secondary schools in Somerset and East Sussex.
Before joining Cardiff Metropolitan University in 1999, David's career in higher education encompassed working for two UK Funding Councils on policy issues associated with both research and teaching, in the process contributing to the national reviews of library provision, performance indicators and research assessment. He has subsequently held planning-related posts at three UK universities.
David has served as a member of the Higher Education Strategic Planners Association and acted as an advisor to JISC sponsored projects. The focus of his professional interest is on factors that lie at the interface of academic and financial imperatives, in particular the development and use of business intelligence, risk management, resource planning and performance systems.Contact Details:


text:
Every Friday, we help you navigate the week's most important and interesting travel news stories.
Every Friday, we help you navigate the week's most important and interesting travel news stories.
Amazing things that should happen more often
The royal baby has yet to be born, but the world is already preparing to welcome the newborn. Celebrations are scheduled around the globe, from baby showers to light shows to gender-reveal cupcakes at US bakery chain Sprinkles. Read more about the festivities here. [The Week]
In-flight entertainment
Photos and videos that went viral on the Web this week
Tourists were lining up to catch a peek – and a sniff – of the rare, oversized and stinky Sumatran plant known as the corpse flower, which was in bloom for just a few days in Belgium's national botanical garden. [AP]
A mapping project called The World: Traced by Runways renders the globe only using airport runways. The painstaking map paints a picture centred on some of the busiest, and also most accessible, places in the world. [Co.Exist]
Ready for takeoff
All set to go, but too soon to tell what's ahead
Qatar is poised to spend a massive $200 billion on football to prep for and host the 2022 World Cup. To put that number in perspective, South Africa spent $2.7 billion on the 2010 World Cup. [Time]
Famous cruise liner the QE2 is prepared to set sail on its final voyage. The ship, which was sold to Dubai World in 2008, will be docked and revamped to operate as a 400-room floating hotel. [Telegraph]
The French have always been known for taking cuisine seriously, and this development just might be the strongest indicator of that. An amendment is making its way through French legislature that, if passed, would require menus to indicate which dishes are made onsite and which come from packages or were purchased readymade. [The Economist]
New Federal Aviation Administration regulations are upping the required flying experience for co-pilots, both in number of hours and type of aircraft training. While the new laws might appear to be in reaction to the Asiana Airlines crash, they actually are related to a 2010 aviation safety law passed following the crash of a regional airplane in upstate New York that killed 50. [AP]
Hold on folks, we're in for a rocky ride
It seems many Death Valley tourists are testing whether it is actually hot enough to fry an egg outside. Rangers have been scraping up a mess of shells and yolks from around the national park, where temperatures have been hitting around 120F. Staff took to their Facebook page to request that visitors please refrain from cracking eggs on the ground. [NBC News]
The captain of the tragically shipwrecked Costa Concordia still has yet to stand trial. The trial was scheduled to begin this week in Tuscany but postponed due to a nationwide lawyer strike. [AP]
It's a no-go
Since Asiana Airlines flight 214 crashed on the runway of San Francisco International Airport on Saturday, claiming two lives and injuring many others, the news cycle has been dominated with investigations and new revelations into the crash, which shocked, scared and confused people around the world. [Time]
The incident generated a number of related articles, including one from The Week decoding plane crash jargon to better help readers understand the news updates.
Like "In brief"? Talk with us on Twitter @BBC_Travel or with the hashtag #bbcinbrief.


text:
World of Warcraft players can now have their own specially designed credit card, although real-world purchases do not translate into virtual currency rewards in the world's most popular online role-playing game.
WoW, with more than 8.5m players worldwide, has combined with Visa and First National Bank of Omaha to offer the card, with Reward Points being awarded that can be exchanged for free playing time. Read more


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Vogue Special Design 5538; ca. 1962; "Easy to Make" One Piece Dress and Bolero. Skirt with gathers at side front and across back joins sleeveless bodice at waist-line. Scooped neck-line. Loop tied belt. Bolero with cut-away front and below elbow length and short sleeves.
Featured in Vogue Pattern Book, December 1962/January 1963
Links to reviews/blog posts Edit
Sources/Vendors Edit
Gallery Edit
[insert your photos of this pattern made up]
Wishlist Edit
[insert your username, and make sure your preferences allow for people to contact you via e-mail. Do not list your email address here!]


text:
By ANAYO OKOLI
UMUAHIA— GOVERNOR Theodore Orji of Abia State has said he would not borrow from the bond market to run affairs of the state, despite its lean resources.
He also said his decision was informed by the need not to bequeath huge debt to the state when leaving office.
The governor said his administration was comfortable with the rate it was carrying on with development of the state, based strictly on the resources coming to it..
Orji, who spoke in Umuahia while interacting with journalists in the state, also disclosed that the Niger Delta Development Commission, of which the state is a member, had taken up 10 roads to rehabilitate in Aba.
This, he explained, was in addition to the 16 his administration was currently working on.
Governor Orji pointed out that when these roads were completed, Aba would wear an entirely new look.
"I am not going to Bond Market. I have been under pressure from many quarters to borrow from the Bond Market. But I said no. We have to cut our coat according to our size. I am happy the way we are going," Orji said.
He said despite the little money accruing to the state, which hovers between N3. 2 and N3. 5 billion monthly, against a monthly wage bill of N1.7 billion, the state was still able to carry out development projects and maintain security.
"The Chief of Army was here and he said that in other states, the Army pays to maintain the soldiers but here in Abia State, the government pays to sustain the soldiers and maintain security.
"As far as I am concerned, I don't regret any amount I pay to maintain security as long as the people who elected me are happy and are enjoying adequate security in the state," the governor said.
Orji also announced that the NDDC had taken up 10 roads, in addition to the ones the state government was doing, as part of efforts to give Aba a facelift.
He said: "NNDC has taken 10 extra roads in Aba which they promised to put in their budget. This will help in the opening up of the city.
"We are also opening up the drainage."


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The best power yoga video should offer various and motivating workouts. It is also essential to choose an instructor who is skilled and well-experienced. A power yoga video should allow various alternatives of the different poses in order that beginners can follow them easily. Two best known teachers are Beryl Bender Birch, who is based in New York, and Bryan Kest, who is based in Los Angeles. They are well-trained by Astanga Master Sri K. Pattabhi Jois.These are some of the great power yoga videos to keep you fit and in shape.Filmed in Santa Monica, California, Bryan Kest's videos are shown giving classes in his famous, full-packed loft studio. Even well-known stars like Rhea Perlman, David Duchovny, and Elisabeth Shue are frequents to this studio. No doubt, Kest's yoga videos are quite popular too. In volume one video, this is a well-rounded workout both for beginners and advance practitioners. Bryan Kest's voice is clear while stretches and strengthening poses are a match even for first timers. The volume two video tackles simple method for toning, and volume three video shows more challenges.Rodney Yee teaches a challenging, poses, controlling breath, movement, tension, and relaxation in his video. These poses are Sun Salutation, standing poses, forward bends, back bends, twists, and arm balances. At first they are quite easy, but movements start to get tougher with each repetition of the series. You can do as much of the series that fits you, it's about 65-minute exercise if you are quite a seasoned and significant yoga consultant.If you are a long practitioner of yoga, you can get started with any level. The setting is very beautiful and interesting. These workouts are designed to help you achieve stronger and flexible body. Rodney Yee's powerful yoga video will help you to expand your practice with more focus on important poses. This is also a fantastic method for maximizing fat burning muscle and bone power; increasing endurance; sculpting your abs, lower and upper body; and offer fluid movements with care. Actions may be a little slow but continuous.This yoga practice videos make you become involved mentally as well. You are moving frequently with Power Yoga. It helps you to build your strength and boost your adaptability. This power yoga video demands your full concentration and sheer slowness all the time. It is a form of meditation too. This power yoga video is reasonably encouraging for many and challenging for others, this exclusive DVD gives bonus, sophisticated option of the exercise with oral cues and music only.Ashes and Snow by Gregory Colbert is an amazing on-going program that joins together the best photographic works, 35mm films, art installations, and a wonderful narration. To get real visual quality and full of life video, this really need a lot of patience and true commitment. This video indicates the wonderful bond between men and animals.
Love the idea of yoga, but aren't sure if it's sufficiently hardcore for you? Don't know if you have the flexibility or balance to get a good yoga burn going? Well, a power yoga workout might be just what the doctor ordered! If you want an invigorating new power yoga workout, try these power yoga workout videos. More yoga videos, DVD's and CD's available!


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Challenging image scoops Simon Devitt award
Alice O'Brien-Gortner in front of her winning work Extinguished (centre top).
Challenging image scoops Simon Devitt award
Alice O'Brien-Gortner, a third-year Bachelor of Architectural Studies student at the University of Auckland has won the 2014 Simon Devitt Prize for Photography with her entry entitled 'Extinguished'.
The competition, now in its sixth year, recognises the best photograph by a student of architecture.
The challenging image was picked as the winner from twenty finalists at the opening last night of an exhibition of contestant's work, on as part of the Festival of Photography.
Simon Devitt, an Auckland-based photographer specialising in architectural images, established the annual award at the School of Architecture and Planning where he teaches the photography of architecture.
Aldous Huxley said 'There are things known and there are things unknown, and in between are the doors of perception.' Photographs are literally made of time. The translation of reality into a photograph creates a medium of pure perception says judge Simon Devitt.
"This year's theme was 'the in-between' and I selected 'Extinguished' as the winning entry because this is where the image seems to live. There is a highly evocative sense of 'another' place we get when we experience this photograph. Alice has created an imagined world that perhaps raises more questions than it answers for the viewer. Her photograph leaves us in a challenging and uneasy place, wondering how we arrived," he says.
Twenty year-old Alice, is originally from Seattle but her family relocated to New Zealand over a decade ago. The Waimauku resident, who receives a trophy and a cash prize of $1,000, hopes to begin a Master of Architecture (Professional) degree next year, but says photography is also a 'major passion' which she plans to pursue.
The 2014 Simon Devitt Prize for
Photography exhibition
28 May-7 June
Foyer, Conference Centre
The University of Auckland
22 Symonds Street
The University of Auckland's National Institute of Creative Arts and Industries comprises the School of Architecture and Planning, Elam School of Fine Arts, the Centre for Art Studies, the School of Music and the Dance Studies Programme.


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WCCC basketball teams have high expectations
Westmoreland County Community College basketball teams have produced their share of memories in six seasons of existence.
Their coaches want more.
"We need more talented kids coming out of Westmoreland County high schools," WCCC men's coach Andrew Colosimo said. "It's there, but most times, a player wants that four-year experience. We're here as an option."
Entering the week, the WCCC women's team was off to a 5-1 start, and the men's squad was 2-2. Both compete in Division III of the National Junior College Athletic Association but frequently load their early-season schedule with Division I and II teams.
As with any two-year junior college, WCCC players quite often look to transfer to four-year NCAA or NAIA schools.
"We've had some talented players," WCCC women's coach Scott Hillen said. "This year, depth-wise, we probably have the most talented group in terms of skill. We've got a little more depth at the guard and forward positions than in other years."
WCCC won 20 games in back-to-back seasons in 2009 and '10, when the Wolfpack were led by Jamie Henry, a 6-foot-1 forward who paced NJCAA Division III with 18.0 rebounds per game during her final season.
Henry transferred to NCAA Division I Cleveland State but left for personal reasons.
While the WCCC men's program most recently had produced several transfers to four-year schools (NCAA Division II California (Pa.) and NAIA Division II Point Park), the current Wolfpack team is led by guard Andy Carter, the Norwin High School product who transferred from NCAA Division III Washington & Jefferson and was leading NJCAA Division III in scoring (30.2 ppg.).
Colosimo said Carter decided to transfer closer to home at WCCC because NCAA Division III schools, such as W&J, do not offer athletic scholarships.
"He's a bright kid, but he was paying too much out of pocket," Colosimo said. "We're trying to get him some help. He's an academic kid, and he'll probably finish this semester with a 4.0 (grade-point average)."
While NCAA Division II schools Slippery Rock and Wheeling Jesuit are keeping close tabs on Carter, Colosimo said, there's plenty of Division I attention for the 6-1 sophomore.
Boston University, Brown, Evansville, Radford, San Jose State and South Dakota have shown interest. Lehigh, Colosimo said, was willing to offer Carter a "preferred walk-on" status.
Every year, WCCC coaches scramble to assemble a roster. But both have been able to sustain success.
"We don't have big numbers on the roster," Hillen said, referring to WCCC's nine-player women's team, "but we usually end up with a solid rotation of seven or eight players."
Leading scorer Danielle Murphy, a Hempfield High School graduate, was expected to return to the lineup this week after being sidelined for three games with a sprained ankle.
"The players have been pushing each other in practice," Hillen said. "The chemistry is there. They all get along on and off the floor. We just don't have big numbers because lot of girls who say they're going to play end up with work schedules that conflict too much. But we've managed to get good enough numbers every year."
Dave Mackall is a staff writer for Trib Total Media. He can be reached at email@example.com or 412-380-5617.


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Wonder of wonders, miracle of miracles, CNN's Jack Cafferty has noticed that Americans are gathering at "Tea Parties" to protest their government's runaway spending and taxation.
Unfortunately, this wasn't done on air, and nowhere in his CNN.com piece did he mention President Barack Obama's name.
However, as his colleagues have largely ignored these protests -- as of Monday they have yet to be mentioned on "The Situation Room" for example -- we shouldn't look a gift horse in the mouth (h/t Glenn Reynolds):
Last week there were protests and demonstrations by taxpayers in cities all around the country who are beginning to object in increasing numbers to runaway government spending, taxes, bailouts and our growing national debt. These protests were called tea parties. Has a familiar ring to it, doesn't it?
This was the conclusion to his commentary which began thusly:
There is a chill wind blowing across this land of ours.
People are losing faith in their ability to realize the American dream. While AIG pays out $165 million in bonuses to people who arguably contributed to the need for the federal government to hand them $170 billion of our money, and while politicians lie about who crafted the language that allowed this kind of stuff to happen (Are you listening Chris Dodd?), the average American is seeing his future disintegrate in front of his eyes.
Oddly, Cafferty didn't mention President Obama or any members of his Administration.
I wonder why.


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Gustavo Dudamel's remarkable Mahler series is fully underway in Los Angeles.
Tonight he conducts Symphony No. 9, and this Saturday Symphony No. 8 is on the programme, complete with the LA Phil, the Simón Bolívar Symphony Orchestra of Venezuela and 16 LA based choirs.
Read more on the LA Phil website and watch our video interview with Gustavo Dudamel below, where he talks about the music of Gustav Mahler.
The US premiere of Georg Friedrich Haas' chants oubliés for chamber orchestra takes place tonight in Los Angeles.
Otto Tausk conducts the LA Phil New Music Group at the Walt Disney Concert Hall.
The title refers to late works by Franz Liszt (Valses oubliés, Romance oubliée) – Liszt's technique of presenting one-part melodies in a different sound environment (often that of the piano) is applied here to the possibilities of the chamber orchestra.


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COM Studies Day
COM Studies Day is a day long celebration of the communication discipline that presents students with the opportunity to engage with alumni and faculty while learning how to successfully take their next steps after college. Through events such as alumni panels and networking sessions, students hear from and interact with grads. The Dress for Success Fashion Show features students as models, skit performers, and producers in an interactive and informative event that teaches students how to dress appropriately and prepare for interviews and other work-related settings. A social concludes the day with additional networking opportunities with alumni, faculty, and department friends. Whether students are entering their last semester at UNCW or just starting out in the major, everyone can receive valuable information from COM Studies Day that will help them prepare for life after graduation.
"The [COM Studies Day] panelists were so inspirational. They gave great advice that can still help us before we graduate."
COM Studies Day 2017: Friday, March 24
Schedule of Events:
10:00 a.m. -- Alumni Panel (Leutze 125)
11:00 a.m. -- Networking Session (Leutze Lobby)
12:15 p.m. -- 15th Annual Dress for Success Fashion Show (Warwick Center Ballroom)
2:00 p.m. -- Alumni Panel (Leutze 125)
3:00 p.m. -- Networking Session (Leutze Lobby)
*all events are free and open to the general public


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Revista da Sociedade Brasileira de Medicina Tropical
Print version ISSN 0037-8682On-line version ISSN 1678-9849
PEDROSA, Roberto Coury; MELO, Marcos F. Vidal and SAAD, Edson A.. Limiar anaeróbio detectado pela "análise da curva-V" na cardiopatia chagásica crônica. Rev. Soc. Bras. Med. Trop. [online]. 1997, vol.30, n.2, pp.129-138. ISSN 0037-8682. http://dx.doi.org/10.1590/S0037-86821997000200008.
Anaerobic threshold (AT) as measured by V-slope, is the best parameter of cardiac reserve in patients with heart failure. A reduction of AT reflects linearly a limited cardiopulmonary reserve in patients with heart disease. We measured the anaerobic threshold from 28 patients (18 men; age 47 ± 6,7 years) classified into four groups: IA (normal ECG, wihout heart disease; 9 patients); IB (normal ECG, early left ventricular segmental abnormalities; 5 patients); II (abnormal ECG, advanced myocardial damage, no signs of heart failure; 7 patients); and III (abnormal ECG, end-stage, congestive heart failure; 7 patients). The analysis of variance indicated that the anaerobic threshold from patients of group IA was significantly greater than in groups IB, II and III (p = 0,001). Tukeys multiple comparation test showed no significative differences between mean AT in groups IB, II and III. The present study clearly demonstrates that occurrence of initial left ventricular contraction abnormalities is associated with definite reduction of cardiopulmonary reserve, and that this reduction is progressive and paralels the hemodynamic alterations. The most probable cause of this finding in group IB is dyastolic dysfunction as clearly showin in echocardiogram.
Keywords : Chronic chagasic cardiopathy; Anaerobic threshold; Test cardiopulmonary; V-slope analysis; Chagas disease.


text: Hanting Hotel(Guilin Railway Station) is a great choice for accommodation when visiting Guilin. With its convenient location, the hotel offers easy access to the neighboring key destinations, like Xiangshan Park. In order to provide the best living experience for you, all rooms are equipped with free toiletries, electric kettle, slippers, television, independent writing desk, hair dryer, complimentary bottled water, etc. Delicately decorated, the hotel also offers many facilities to enrich your stay here, including wake-up calls, room service, tourism service, closed circuit television in public area and so on. Opened in 2013, the hotel houses 105 rooms and suites.


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The NCAA granted Michigan quarterback Devin Gardner a medical hardship for his 2010 season, leaving him with two years of eligibility.
The University of Michigan Athletic Department announced today (Tuesday, March 5) that senior/junior quarterback Devin Gardner (Detroit, Mich./Inkster) has been granted a medical hardship for the 2010 season and will have two seasons of eligibility remaining.
Gardner appeared in three games in 2010 as a true freshman before suffering a season-ending back injury.
Ryan Shazier, when reached for comment, allegedly nodded and smiled. Probably.


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Product Summary
AMD Phenom II is for high definition entertainment, gaming, creativity, and beyond. With AMD Phenom II processors as the foundation, you'll enjoy a new level of responsiveness and visual intensity. AMD puts high definition computing within everyone's reach. AMD Phenom II processors have the power to do it all. Featuring next-generation Quad-core design, they crush even the most demanding tasks. So design it, render it, play it, create it, stream it, HD it. With AMD Phenom II processors, if you can imagine it, you can do it. AMD Phenom II processors were designed with energy efficiency in mind. Capitalizing on AMD's leadership in energy efficiency, they incorporate all of the latest technology that gives you performance when you need it and save power when you don't.
General Information
|Product Type
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|Advanced Micro Devices, Inc
|Product Model
|Product Name
|Phenom II X4 Quad-core 965 3.4GHz Processor
|Product Line
|Phenom II X4
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Technical Information
|Process Technology
|45 nm
|Clock Speed
|3.40 GHz
|Processor Socket
|Socket AM3 PGA-941
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|AMD64 Technology
|CoolCore Technology
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|4000 MHz
|Platform Supported
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BURY ABC boxer Muhammad Ali has been picked to fight for Great Britain in the 2014 Youth Olympics.
The 17-year-old, who recently won a silver medal at the world championships, is one of only three British boys to have qualified for the event, which kicks off on August 16 in Nanjing, China.
Coach Mick Jelley, who trained Amir Khan in his early career and helped him to qualify for the 2004 Athens Olympics, where he won silver, believes Ali has the potential to repeat that success.
"If you want to put this kid's achievements into context, I would say that over the past 50 years this country has only produced five boxers who have won world amateur medals," he said.
"Amir Khan is one of them and young Ali is another. Amir won gold at the worlds before he went to Athens, whereas Ali came back with silver, but he also has seven national titles to his name, which I think is more than Amir had at the same age."
Ali, who will go for gold in the 52k division, returned home last weekend from a Team GB training camp in China. Jelley believes he has the work ethic to go all the way to the top, but has quelled talk of a possible call-up to the senior Olympic squad heading off to the Rio Games in 2016.
"You don't achieve anything in life if you are not prepared to put the work in and Ali certainly does that," he said.
"He works very hard and has the ability and attitude to go far.
"Other than Amir, he is the only other lad from this boxing club to be picked for an Olympic squad, but I am afraid, even though I believe he is probably good enough, he won't be going to the Rio Games.
"Team GB have already chosen a squad of 10 boxers who they will be putting forward for the qualifying tournaments, so Ali will have to wait for the next one in Tokyo, if he hasn't turned pro before then."


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Chuck Seelbach
Charles Frederick Seelbach
- Bats Right, Throws Right
- Height 6' 0", Weight 180 lb.
- School Dartmouth College
- Debut June 29, 1971
- Final Game May 23, 1974
- Born March 20, 1948 in Lakewood, OH USA
Click on edit above to add biographical information[edit]
Most of Chuck Seelbach's major league innings were with the 1972 Tigers when he had a 2.89 ERA in 112 innings. He had a 9-8 record with 14 saves, good for seventh in the league. His teammates included Al Kaline and Norm Cash, both 37 at the time.
He currently is a history teacher at University School in Hunting Valley, Ohio.
Both he and pitcher Pete Broberg were at Dartmouth College in 1970.


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Home > Specials > Environment > Article
The world's first macadamia nut-fuelled powerplant was officially opened today at Gympie, north of Brisbane.
The Macadamia Cogeneration Facility will use the discarded shells of the nuts to power up to 1200 Queensland homes in its first year.
The $3 million "green power" facility is a joint venture between the Queensland government-owned Ergon Energy and the Gympie-based Suncoast Gold Macadamias company, the world's third-largest producer of the nuts.
Queensland Energy Minister Paul Lucas flicked the ceremonial switch today and said 80 per cent of the power generated at the environmentally-friendly site would be exported to the national electricity grid.
"Each hour this facility will convert 1680 kilograms of waste shell into 1.5 megawatts of electricity," Mr Lucas said.
"In its first year of operation the facility will reduce greenhouse gases by around 9500 tonnes which is the equivalent of taking more than 2000 cars off the road."
Mr Lucas said within the next two years the facility is expected to double its output by using 10,000 tonnes of waste shells - enough to fill five Olympic-size swimming pools.
The plant had generated interest from the United States, the United Kingdom, Africa and Asia, Mr Lucas said.
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As expected, the counties have decided that the best prospect of change is to focus on the temporary motions from Sligo, Wicklow and Roscommon.
These call for Croke Park to be made available to the IRFU and FAI during the redevelopment of Lansdowne Road.
For motions to succeed, they need to be endorsed by a two-thirds majority.
While a significant majority of southern counties are in favour of change on the Croke Park issue, the vote on 16 April could well be defeated because of Ulster opposition.
Apart from Cavan, and possibly Donegal, all the other Ulster counties seem set to vote against an historic change and the opposition of the northern province could spell the death knell for the proposal.
The Roscommon motion calls for Croke Park to be opened for a three-year period from this April while the Sligo and Wicklow proposals refer to the period of redevelopment work at Lansdowne Road.
Roscommon official Tommy Kenoy has said that it would be "pointless putting forward seven motions".
"If the first one fails then the same thing will probably happen to the rest of them," he told the Irish Times.
"But even the temporary motions have a slightly different wording, so we'll have to decide which of the three is the most favourable.
"Roscommon are saying let it be opened for three years and then bring it back to Congress in 2008."
Waterford, Tipperary, Meath and Limerick are among counties who will consider the temporary motions in the coming days.
Current GAA president Sean Kelly is in favour of making the historic change but there is a difference of opinion among the two men who will contest the election to succeed the Kerryman.
Nicky Brennan agrees with Kelly's viewpoint but the other presidential candidate Christy Cooney favours the status quo.


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Contained Places
Kerala, often referred to as Keralam, is a state in the south-west region of India on the Malabar coast. It was formed on 1 November 1956 as per the States Reorganisation Act by combining various Malayalam-speaking regions. Spread over it is bordered by Karnataka to the north and north east, Tamil Nadu to the east and south, and the Lakshadweep Sea to the west. With 33,387,677 inhabitants as per the 2011 census, Kerala is the thirteenth largest state by population and is divided into 14 districts with the state capital being Thiruvananthapuram. Malayalam is the most widely spoken and official language of the state.
The region was a prominent spice exporter from 3000 BCE to 3rd century. The Chera Dynasty was the first powerful kingdom based in Kerala, though it frequently struggled against attacks from the neighbouring Cholas and Pandyas. During the Chera period, Kerala remained an international spice trading center. Later, in the 15th century, the lucrative spice trade attracted Portuguese traders to Kerala, and eventually paved the way for the European colonisation of India. After independence, Travancore and Cochin joined the Republic of India and Travancore-Cochin was given the status of a state. Later, the state was formed in 1956 by merging the Malabar district, Travancore-Cochin (excluding four southern taluks), and the taluk of Kasargod, South Kanara.
Kerala is the state with the lowest positive population growth rate in India (3.44%) and has a density of 860 people per km2. The state has the highest Human Development Index (HDI) (0.790) in the country according to the Human Development Report 2011. It also has the highest literacy rate 93.91%, the highest life expectancy (almost 77 years) and the highest sex ratio (as defined by number of women per 1000 men: 1,084 women per 1000 men) among all Indian states. Kerala has the lowest homicide rate among Indian states, for 2011 it was 1.1 per 100,000. A survey in 2005 by Transparency International ranked it as the least corrupt state in the country. Kerala has witnessed significant emigration of its people, especially to the Gulf states during the Gulf Boom of the 1970s and early 1980s, and its economy depends significantly on remittances from a large Malayali expatriate community. Hinduism is practised by more than half of the population, followed by Islam and Christianity. The culture of the state is a synthesis of Aryan and Dravidian cultures, developed over millennia, under influences from other parts of India and abroad.
Production of pepper and natural rubber contributes to a significant portion of the total national output. In the agricultural sector, coconut, tea, coffee, cashew and spices are important. The state's coastline extends for , and around 1.1 million people of the state are dependent on the fishery industry which contributes 3% of the state's income. The state's of roads, constitute 4.2% of all Indian roadways. There are three existing and two proposed international airports. Waterways are also used for transportation. The state has the highest media exposure in India with newspapers publishing in nine different languages; mainly English and Malayalam. Kerala is an important tourist destination, with backwaters, beaches, Ayurvedic tourism, and tropical greenery among its major attractions.
Prehistorical archaeological findings include dolmens of the Neolithic era in the Marayur area in Idukki district. They are locally known as "muniyara", derived from muni (hermit or sage) and ara (dolmen). Rock engravings in the Edakkal Caves (in Wayanad) are thought to date from the early to late Neolithic eras around 6000 BCE. Archaeological studies have identified many Mesolithic, Neolithic and Megalithic sites in Kerala. The studies point to the indigenous development of the ancient Kerala society and its culture beginning from the Paleolithic age, and its continuity through Mesolithic, Neolithic and Megalithic ages. However, foreign cultural contacts have assisted this cultural formation. The studies suggest possible relationship with Indus Valley Civilization during the late Bronze Age and early Iron Age.
Ancient period
Kerala was a major spice exporter from as early as 3000 BCE, according to Sumerian records. Its fame as the land of spices attracted ancient Babylonians, Assyrians and Egyptians to the Malabar Coast in the 3rd and 2nd millennia BCE. Arabs and Phoenicians were also successful in establishing their prominence in the Kerala trade during this early period. The word Kerala is first recorded (as Keralaputra) in a 3rd-century BCE rock inscription (Rock Edict 2) left by the Maurya emperor Ashoka (274–237 BCE). The Land of Keralaputra was one of the four independent kingdoms in southern India during Ashoka's time, the others being Chola, Pandya, and Satiyaputra. Scholars hold that Keralaputra is an alternate name of the Cheras, the first powerful dynasty based on Kerala. These territories once shared a common language and culture, within an area known as Tamiḻakam. While the Cheras ruled the major part of modern Kerala, its southern tip was in the kingdom of Pandyas, which had a trading port sometimes identified in ancient Western sources as Nelcynda (or Neacyndi). At later times the region fell under the control of the Pandyas, Cheras, and Cholas. Ays and Mushikas were two other remarkable dynasties of ancient Kerala, whose kingdoms lay to the south and north of Cheras respectively.
In the last centuries BCE the coast became famous among the Greeks and Romans for its spices, especially black pepper. The Cheras had trading links with China, West Asia, Egypt, Greece, and the Roman Empire. In the foreign-trade circles the region was identified by the name Male or Malabar. Muziris, Berkarai, and Nelcynda were among the principal ports at that time. The value of Rome's annual trade with India as a whole was estimated at no less than 50,000,000 sesterces; contemporary Sangam literature describes Roman ships coming to Muziris in Kerala, laden with gold to exchange for pepper. One of the earliest western traders to use the monsoon winds to reach Kerala may have been Eudoxus of Cyzicus, around 118 or 166 BCE, under the patronage of Ptolemy VIII, a king of the Hellenistic Ptolemaic dynasty in Egypt. Various Roman establishments in the port cities of the region, such as a temple of Augustus and barracks for garrisoned Roman soldiers, are marked in the Tabula Peutingeriana: the only surviving map of the Roman cursus publicus.
Merchants from West Asia and Southern Europe established coastal posts and settlements in Kerala. Jewish connection with Kerala started as early as 573 BCE. Arabs also had trade links with Kerala, possibly started before the 4th century BCE, as Herodotus (484–413 BCE) noted that goods brought by Arabs from Kerala were sold to the Jews at Eden.[1] They intermarried with local people, and from this mixture the large Muslim Mappila community of Kerala are descended. In the 4th century, some Christians also immigrated from Persia and joined the early Syrian Christian community who trace their origins to the evangelistic activity of Thomas the Apostle in the 1st century. Mappila was an honorific title that had been assigned to respected visitors from abroad; and Jewish, Syrian Christian, and Muslim immigration might account for later names of the respective communities: Juda Mappilas, Nasrani Mappilas, and Muslim Mappilas. According to the legends of these communities, the earliest Christian churches, mosque, and synagogue (1568 CE) in India were built in Kerala. The combined number of Jews, Christians, and Muslims was relatively small at this early stage. They co-existed harmoniously with each other and with local Hindu society, aided by the commercial benefit from such association.[2]
Early medieval period
Much of history of the region from the 6th to the 8th century is unknown.[3] A Second Chera Kingdom (c. 800–1102), also known as Kulasekhara dynasty of Mahodayapuram, was established by Kulasekhara Varman, which at its zenith ruled over a territory comprising the whole of modern Kerala and a smaller part of modern Tamil Nadu. During the early part of Kulasekara period, the southern region from Nagerkovil to Thiruvalla was ruled by Ay kings, who lost their power in the 10th century and thus the region became a part of the Kulasekara empire. During Kulasekhara rule, Kerala witnessed a flourishing period of art, literature, trade and the Bhakti cult of Hinduism. A Keralite identity, distinct from the Tamils, became linguistically separate during this period. For the local administration, the empire was divided into provinces under the rule of Naduvazhis, with each province comprising a number of Desams under the control of chieftains, called as Desavazhis.[4] Later in the 18th Century, Travancore King Sree Anizham Thirunal Marthanda Varma annexed all kingdoms up to Kochi through military conquests, resulting in the rise of Travancore to a position of pre-eminence in Kerala.
The inhibitions, caused by a series of Chera-Chola wars in the 11th century, resulted in the decline of foreign trade in Kerala ports. Buddhism and Jainism disappeared from the land. The social system became fractured with internal divisions on the lines of caste. Finally, the Kulasekhara dynasty was subjugated in 1102 by the combined attack of Later Pandyas and Later Cholas.[5] However, in the 14th century, Ravi Varma Kulashekhara (1299–1314) of the southern Venad kingdom was able to establish a short-lived supremacy over southern India. After his death, in the absence of a strong central power, the state was fractured into about thirty small warring principalities; most powerful of them were the kingdom of Samuthiri in the north, Venad in the south and Kochi in the middle. Later in the 18th Century, Travancore King Sree Anizham Thirunal Marthanda Varma annexed all kingdoms up to Northern Kerala through military conquests, resulting in the rise of Travancore to a position of pre-eminence in Kerala. The Kochi ruler sued for peace with Anizham Thirunal, Malabar came under direct British rule till Independence.
Colonial era
The monopoly of maritime spice trade in the Indian Ocean stayed with Arabs during the high and late medieval periods. However, the dominance of Middle East traders got challenged in the European Age of Discovery during which the spice trade, particularly in black pepper, became an influential activity for European traders. Around the 15th century, the Portuguese began to dominate the eastern shipping trade in general, and the spice-trade in particular, culminating in Vasco Da Gama's arrival in Kappad Kozhikode in 1498. The Zamorin of Kozhikode permitted the new visitors to trade with his subjects. The Portuguese trade in Kozhikode prospered with the establishment of a factory and fort in his territory. However, Portuguese attacks on Arab properties in his jurisdiction provoked Zamorin and finally led to conflicts between them. The Portuguese took advantage of the rivalry between Zamorin and king of Kochi; they allied with Kochi and when Francisco de Almeida was appointed as the Viceroy of Portuguese India in 1505, his headquarters was at Fort Kochi (Fort Emmanuel). During his reign, the Portuguese managed to dominate relations with Kochi and established a few fortresses in Malabar coast. Nonetheless, the Portuguese suffered severe setbacks from the attacks of Zamorin forces; especially from naval attacks under the leadership of admirals of Kozhikode known as Kunjali Marakkars, which compelled them to seek a treaty. In 1571, Portuguese were defeated by the Zamorin forces in the battle at Chaliyam fort.
The weakened Portuguese were ousted by the Dutch East India Company, who took advantage of continuing conflicts between Kozhikode and Kochi to gain control of the trade. The Dutch in turn were weakened by constant battles with Marthanda Varma of the Travancore Royal Family, and were defeated at the Battle of Colachel in 1741. An agreement, known as "Treaty of Mavelikkara", was signed by the Dutch and Travancore in 1753, according to which the Dutch were compelled to detach from all political involvements in the region. In the meantime, Marthanda Varma annexed many northern kingdoms through military conquests, resulting in the rise of Travancore to a position of preeminence in Kerala.
In 1766, Hyder Ali, the ruler of Mysore invaded northern Kerala. His son and successor, Tipu Sultan, launched campaigns against the expanding British East India Company, resulting in two of the four Anglo-Mysore Wars. Tipu ultimately ceded Malabar District and South Kanara to the Company in the 1790s; both were annexed to the Madras Presidency of British India in 1792. The Company forged tributary alliances with Kochi in 1791 and Travancore in 1795. Thus, by the end of 18th century, the whole of Kerala fell under the control of the British, either administered directly or under suzerainty.
Post colonial period
After British India was partitioned in 1947 into India and Pakistan, Travancore and Kochi, both part of the Union of India were merged on 1July 1949 to form Travancore-Cochin. On 1November 1956, the taluk of Kasargod in the South Kanara district of Madras, the Malabar district of Madras, and Travancore-Cochin, minus four southern taluks (which joined Tamil Nadu), merged to form the state of Kerala under the States Reorganisation Act.
A Communist-led government under E. M. S. Namboodiripad resulted from the first elections for the new Kerala Legislative Assembly in 1957.[6] It was one of the earliest elected Communist governments, after Communist success in the 1945 elections in the Republic of San Marino (a city-state surrounded by Italy).
Research Tips


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Posted by ESPN.com's Tim Griffin
While developing a list of the top 12 non-conference matchups Thursday, I began thinking about ideal matchups for different schools across the conference.
If I were king of college football and could mandate opponents for different Big 12 teams, here are some of the choices I'd make and my reasoning. Let me know what you think, and if you could come up with better ones.
Baylor -- How about Vanderbilt? What could be better than watching two schools that face similar difficulties from the nation's toughest conferences? Both are private schools and have the benefit of strong coaches. It would be an entertaining game.
Colorado -- I originally thought Air Force would work because of the geographical proximity. But a better choice, I think, is UCLA, so we could watch Rick Neuheisel squaring off against his old team. And the two programs are relatively equal, which should make for some real competition on the field.
Iowa State -- You could argue for Florida and a return of Dan McCarney to Ames. But a better, more entertaining game would be to match the Cyclones against Minnesota. The two schools are relatively close and are at about the same levels in their respective conferences. You could bet that Mack Brown would be watching the matchup of his old protégés Gene Chizik and Tim Brewster.
Kansas -- ESPN has liked matching the coaching wiles and offenses of Mark Mangino and Toledo's Tom Amstutz in the past. But a better matchup would be to let Mangino call plays against Joe Paterno and Penn State. Jayhawks fans are still grouchy about how the 1969 Orange Bowl finished up. It would be kind of neat to see a rematch -- even if it's nearly 40 years later.
Kansas State -- Give me the Wildcats and Fresno State, the school they ducked earlier this season. I don't know what Ron Prince is afraid of. His Wildcats would match up very favorably with the Bulldogs.
Missouri -- There was a lot of bluster emanating out of Iowa City a couple of years ago when the Tigers and Iowa abruptly cancelled a series of upcoming games. But things have changed since then. The Tigers are white-hot and the Hawkeyes have taken a big step back. Let's see them finally play.
Nebraska -- It's hard to think of many for the Cornhuskers, who have played virtually every great national program in the past. I'd like to see them challenge South Carolina right now. I know that Steve Spurrier hasn't forgotten that 62-24 bludgeoning his Florida Gators endured at the hands of the Cornhuskers in the 1996 Fiesta Bowl. And the coaching battle between Spurrier and Bo Pelini would be delicious.
Oklahoma -- I used to think seeing Bob Stoops match wits with Spurrier would be neat. But a better matchup might feature the Sooners against Florida -- a game between two of the nation's most talented programs in recent history.
Oklahoma State -- It might be kind of cool to see the Cowboys square off with Les Miles' LSU team or the Southern Mississippi team now coached by Larry Fedora. But a better game -- and definitely more anticipated media scrum afterward -- would be to see the Cowboys meet Michigan State and Coach Mark Dantonio. The game would be close on the field and the fireworks after the game with Mike Gundy and Dantonio might be better than the game before it.
Texas -- After watching a BCS title game that lived up to the hype (and more), I could watch Texas against USC every day for the rest of my life. These two programs really should play more often, even if Vince Young and Reggie Bush don't have any eligibility remaining.
Texas A&M -- The rivalry for recruiting in East Texas is pretty intense and I think it would be kind of fun to see the Aggies hook up against Les Miles and LSU. The two old rivals played 49 times between 1899 and their most recent skirmish in 1995. It would be good to see them playing again.
Texas Tech -- Mike Leach once roamed the sidelines at BYU, where he intently watched coach LaVell Edwards' practices as a student. Those early sessions enabled him to glean some of the bedrock principles for his passing offense. Who says you can't go home again? A game between the Red Raiders and the Cougars would provide the kind of offense that fans dream about.
Let me know what you think and suggest some other potential dream non-conference games. I'll let others know about your choices.


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by Bob Grawey
Staff writer
For years people have seen Hardee's, a fast food burger chain, disappear from the retail landscape.
But the company is beginning to rebound, and residents can expect to see a new Hardee's built this year in Hassan.
It will be located in the KinderCare development on 141st Avenue North between Highway 101 and Northdale Boulevard.
Hassan Town Board members approved the new fast food venture May 2.
It is phase II of the KinderCare development that was built in 2007. A future phase III addition would bring more stores into the development.
Construction is expected to begin sometime this year, and owner Tom Hoff and his representatives indicated at the town board meeting that they want to open the fast food store yet this year.
Much discussion surrounded potential traffic tie-ups on Northdale due to the expected business at Hardee's.
It is already common for several vehicles to back up at the Northdale/141 intersection waiting for traffic to clear, especially when schools let out from both directions along 141/144.
Hardee's representatives explained to Hassan officials that they are planning to construct double lanes exiting from the development onto Northdale. They said this would stack traffic in the parking lot rather than adding to back-ups on the street.
One thing Hardee's did not get was a pylon sign. These are the big signs on high poles that can be seen from a great distance.
Hardee's owners had also wanted an electronic message sign lower on the requested pylon sign in order to advertise specials, but town board members flatly refused that request, too, saying such signage was not allowed in Hassan.
Board members did allow a drive-through, however.
They also made provisions that the fast food business would fit in aesthetically with other businesses in the development through signage, building materials and landscaping.


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CINCINNATI — With two sacks and a key pass breakup, senior LB Sabbath Joseph stepped up against a prolific Cincinnati offense Friday night, but the highlight of his week came Tuesday, when he became a father with the birth of his daughter, Kalani.
That made it an emotional game for Joseph, who asked all his teammates to find someone special to dedicate the game.
"It meant a great deal," Joseph said. "This whole week has been a big experience for me. I told the guys, 'We're not where we want to be as a team, but just come out here and if there's anything you play the game for, let it be tonight. Whether it be a grandma, an uncle, cousin, friend, anything that inspires you. Come out and give it your all. None of this would be possible without God, so lay it on the line with every breath he gives you.' "
Joseph made a key stop on fourth and 1 when Cincinnati went for it late in the third quarter. On the next play, the Bulls struck for a 70-yard touchdown pass from B.J. Daniels to Faron Hornes for a 15-point lead.
OTHER SIDE: For the third time in a key game this season, the Bulls made a pivotal mistake in the final 90 seconds of the first half, though the Bearcats made their own mistake to limit the damage to USF.
The offense has struggled late in the first half, with Daniels throwing interceptions that led to touchdowns against Florida and West Virginia. On Friday, the defense made the mistake, allowing not only a third-and-20 conversion in the final minute but a long pass to WR Marcus Barnett that looked to be a tying 68-yard touchdown.
But Barnett got a little careless near the sideline, stepping out of bounds at the 4-yard line right before he dived into the end zone.
That's when the Bulls defense stepped up with 1:20 left in the half, coming up with three stops and forcing the Bearcats to settle for a 22-yard field goal.
BEEN A WHILE: When the Bulls took a 7-3 lead early in the second quarter, it marked their first lead in Nippert Stadium since early in the 2004 game, a span that was three minutes short of three full games. The Bulls never led in losses to the Bearcats here in 2006 and 2008.
BACK DEEP: Redshirt freshman walk-on Jonny Sitton, who briefly had the punt return job in the opener before losing a fumble, was back deep Friday, returning Cincinnati's first punt 12 yards. With regular returner Terrence Mitchell trying a switch from cornerback to receiver this week, the Bulls apparently wanted to let him focus on that and put Sitton, an Indian Rocks Christian graduate, in for punt returns.
KICKING GAME: Maikon Bonani, who connected on a 33-yard field goal in the second quarter, is 6-for-7 on field goals since taking over for Eric Schwartz, who went 1-for-5 to start the season.


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Dev - Also, on form submission, use GD to resize the image as a new thumbnail file
Dev - In the submission form, you can now upload a banner image
Sim Vassal
Don't be thrown into thinking you have no control by the different resource system. Instead of gathering metals or wood, you can employ 'serfs' to work on your land. At the end of the year each serf pays 50 gold in taxes and your fields are harvested giving you a certain amount of gold.
Pay attention to the instructions given to you in the first year as they will help you progress faster and stay alive longer. Upon winning you will recieve a code, pm it to me if you want your win proven to others, use it in the game and you'll have another prize...
Please note that this game temporarily changes your resolution to 640x480.
Though the music contributes heavily to mood (you'll see at the end) you may turn it off with <m>, to turn it back on press <k>.
Thank you for playing Sim Vassal.
And thank Lost Dragon for the sprites - they're great!
Target platforms:
This game looks awesome!!! Downloading...
Yeah, this game was very good...I think it could've used a tad bit more work...but very good for the most part...wasn't even that complex either...
Here are the pros...
-fitting music
-fun gameplay
-cool theme
-good display
-good enough setup of menus and such
-Pretty decent graphics
-Lacking in things to do;repetitive
-bit...I dunno...
Overall it was great...I just think that if you had worked on it more, it could've been even better...but I think where you had stopped is fine. Good job, 9/10...
Quote: TG the friendly ghost
the graphics all fit well
Ack, he used graphics from http://www.molotov.nu/?page=graphics they're not original.
Anyway, this game seems pretty good, I'll play it later.
Easy? Well you must have had plenty of gold then. I lost more and more every round. This game is too random where it should be random and not random enough where it should be (eg. the enemies does the same thing when you start over).
It's nice that you have smart pathfinding but use A*... half the time the people went in the wrong direction.
As has already been stated this game is too repetative. I lacked things to do. Things to upgrade. And more stuff. It feels like this is made in DnD.
Bad things apart this game was actually pretty good. I liked the whole feel about it. The music was nice though a bit short for something that constantly loops. Oops I forgot that I was done with the bad parts. Well enough said.. I liked it. 8/10
Very interesting RTS game. When it changed resolution, though, it messed with the computer's screen, allowing it to be offset. You should make a windowed mode that doesn't change resolution.
Well, there wasn't really much to do, but it's got a lot of the essentials it needs to be a really good RTS. It was a lot of fun. 9/10
Thanks for all your wonderful comments; I know it's been over half a year but the updated version is now up! This version introduces a difficulty setting with the old difficulty at 10 and the easiest at 1. In addiction a few more tutorial features have been added like tips from a game over and a prompt telling you when you can skip to the next winter.
Have fun :)


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32nd Annual Hallockville Fall Festival and Craft Show
This event has already taken place. Click here for the latest events.15-09-2012 12:00:00 16-09-2012 12:00:00 America/New_York 32nd Annual Hallockville Fall Festival and Craft Show | 10am-5pm A North Fork traditional country fair featuring artisan vendors, food, music, children's games, animals and demonstrations of traditional crafts. Proceeds from the event support the non-profit museum. http://www.nymetroparents.com/2015neweventinfo.cfm?id=116765 Hallockville Museum Farm Hallockville Museum Farm
If you go: Please tell them you saw this event on
Upcoming Events at Hallockville Museum Farm:


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Includes information on how to apply for visitor visas, bridging visas and transit visas and what you can bring into Australia.
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This information is for people who have already been granted a Student Guardian visa (subclass 580) or for people who applied for the visa on or before 30 June 2016 and for which a decision has not yet been made. It explains your rights and obligations.
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There are two ways you can make alterative welfare arrangements:
We will tell you if the alternative welfare arrangements have been approved. If we decide that the welfare arrangements are not suitable, you cannot leave Australia without your nominating student.
You must comply with the visa's 'no further stay' condition. This means that you cannot apply to stay in Australia beyond the date specified on your visa, except in certain circumstances.
You must not work while in Australia. If you don't abide by the conditions of your Guardian visa (subclass 580), your visa might be cancelled, and we could also cancel the nominating student's visa.
You must tell us if your circumstances change. This includes a new residential address, a new passport, or a pregnancy, birth, divorce, separation, marriage, de facto relationship or death in your family.
Please report changes in your circumstances via ImmiAccount. If you are not able to use ImmiAccount, you can use the following forms:


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Chibi Maruko
An easy knit cowl featuring a beautiful textured stitch that is easy to knit and quick to memorize. This cowl can be knit with a variety of yarn weights and a satisfying quick-knit project. It's also a great way to use up those odd skeins of heavier weight yarns. The pattern includes tips on customizing the size of your cowl. Please note that changing the size will also alter the amount of yarn required.
This cowl can be knit in a variety of yarns and weights at different gauges. Feel free to experiment! The smaller cowl uses an aran weight yarn, shown in Blue Sky Alpacas Extra, is knit with larger needles and gauge making it a super quick knit. The larger cowl is worked in worsted weight, shown here in Louet Gems Worsted weight.
Finished Size
Small: 11" x 71⁄2" (folded)
Large: 131⁄2" x 91⁄2" (folded)
Small shown in:
• Blue Sky Alpacas Extra, 218 yd/150g; 55% alpaca, 45% merino: 1 skein shown in #3517 Nocturne.
Large shown in:
• Louet Gems Worsted Weight, 175 yd/100g; 100% merino: 2 skeins shown in #26 Crabapple.
• US 9 (6 mm) 24" circular knittng needles for small cowl.
• US 7 (4.5 mm) 24" circular knitting needles for large cowl.


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from fort wayne, IN
Really surprised by how well this shirt looks. I've bought other shirts online and their graphics looked poor as if they'd fall of the moment they were put in the wash, but this shirt looks amazing and I'm sure it will last for a very long time.
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Punjabi Dal Makhani
READY IN: 8hrs 20mins
Recipe by udita
A Punjabi mixed lentil curry generally made with lots of butter and cream.This recipe tastes even better the following day after reheating properly.
Top Review by freddiebaby
This was a great recipe and one that I now incorporate into our regular rotation. We are vegan so I replaced the butter with vegan margarine and the cream with Belsoy (a soy-based cream. Delicious for the whole family! Thank you for sharing this recipe!
Ingredients Nutrition
- 3⁄4 cup Urad Dal (black matpe beans)
- 1⁄4 cup red kidney beans (rajmah)
- 2 teaspoons cumin seeds
- 8 garlic cloves, chopped
- 2 inches gingerroot, chopped
- 1 teaspoon garam masala powder
- 1⁄2 cup fresh cream
- 1 teaspoon red chili powder
- 3 tablespoons butter
- 2 tomatoes, chopped (extra large tomatoes)
- 1 onion, chopped
- 1 tablespoon oil
- salt
Directions See How It's Made
- Soak whole black urad and rajma overnight in 3-4 cups of water.
- Cook the soaked dal and rajma in the same water with salt, red chili powder and half the chopped ginger till dal and rajma are cooked and soft.
- Peel and chop the onion, ginger and garlic finely. Also chop the tomatoes.
- Heat oil and butter in a thick-bottomed pan. Add cumin seeds, when it crackles add chopped onions and fry till golden brown.
- Add chopped ginger, garlic and chopped tomatoes. Sauté till tomatoes are well mashed and fat starts to leave the masala. Add boiled dal and rajma to this.Do not add the liquid at first.Crush(mash) the dals with the back of the ladle while stirring continuously, this gives that creamy texture to the dal .
- Add the liquid and some water if required and simmer on very low heat for fifteen minutes.
- Add fresh cream and garam masala powder let it simmer for another five minutes. Finish off with a couple of pinch of Kasoori methi powdered.
- Serve hot with Naan or Paraatha.
- Tip: Replacing the tomatoes with 4 tablespoons of thick tomato paste will enhance the taste and colour of the dish manifold.


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BrittanyNS Model
Ian PowellPhotographer Male Columbus, Ohio, US
My Website: my websiteMy MM URL: http://www.modelmayhem.com/ian
Mayhem # 207
About Me
I'm an classically trained photographer from Columbus Ohio. I have a cinematic perspective and a strong aesthetic. I do a lot of work in the music scene and related events here in Columbus.
Educated at Hofstra University in both Cinematography and Photography. Received a BA in Cinematography and related fields. My Professors said that I have that unique unattainable gift for visual design that one really needs to provide images that create artistic impact and appeal.
Have you worked with Ian Powell? Add Credits for Ian Powell! >>
Credit Notes
Shot and or directed 6 student films at Hofstra univiersity
Extensively studied photography and cinematography at Hofstra University.
Published in
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Hitless Wonder: A Life In Minor League Rock And Roll by Joe Oestreich, Lyons Press June 5 2012
Now It's Dark January & February 2015
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Make a red carpet entrance with these stunning Amethyst and Amethyst Ab Swarovski crystal elongated leaves style earring.
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1 head of cabbage finely shredded
2 carrots, shredded
2 tsp dried or fresh onion (minced)
1 bell pepper, any color, finely minced
2 tsp. Old Bay seasoning or 1 tsp celery seed
1 tsp. salt
1 tsp ground black pepper
1/2 cup lemon juice
1/4 cup cider vinegar
1 1/2 cup sugar
1/4 cup yellow mustard
A few dashes hot sauce
Combine sauce ingredient and whisk. Pour over the remaining ingredients and toss until well coated. Serve immediately or refrigerate.
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© 2017 Cuisinart. All Rights Reserved.


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Men's Sports
Women's Sports
Men's Sports
Women's Sports
May 25, 2007
ATHENS, Geo. - The women's doubles duo of Sylvia Kosakowski and Bianca Dulgheru moved into the round of eight with their victory Friday, but Andre Begemann saw his run come to an end in singles play on the men's side.
Kosakowski and Dulgheru claimed a 6-3 first-set victory over Northwestern's duo of Alexis Prousis and Georgia Rose. The Pepperdine tandem had a chance to pull out the second set by the same score but Northwestern's team was able to hold serve and pulled within one, 5-4. On Kosakowski's serve the Waves went up 40-30 but lost consecutive points and were looking at break point twice before sealing the match.
The Pepperdine duo will have their hands full in the quarterfinal round Saturday as they are scheduled to face the tournament's No. 4 seed in Ana Cetnik and Anna Sydorska of TCU.
Begemann had his run in this year's tournament come to an end in the round of 16 after dropping a tightly contested battle 7-6 (4), 6-4 to the tournament's No. 6 seed Arnau Brugues of Tulsa.
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