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WKU geography team investigates agritourism changes in Sicily
|Date: Wednesday, July 23rd, 2014
A team of researchers from WKU's Department of Geography and Geology spent a week in southern Sicily at the beginning of July to investigate changes in the agritourism landscape.
Led by Associate Professor of Geography Dr. Peggy Gripshover, and accompanied by Dr. Thomas Bell (adjunct Professor of Geography), University Distinguished Professor of Geography Dr. David Keeling, Mammoth Cave National Park Senior Ranger Chuck Decroix, Geography and Geology Office Manager Wendy Decroix (studying agritourism as part of an independent study abroad course), and WKU-Navitas instructor DJ Urquhart, the group explored recent socio-economic changes in local landscapes, resources, culture and the environment.
The group stayed at a working olive plantation in order to gain first-hand experience of the olive-oil production and marketing process, and to understand more clearly the strategies engaged in rebranding the regional terroir (a French term for the geography, geology and climate characteristics that influence the production of agricultural products).
Sicily has long struggled as a regional economic backwater of Italy, with the landscape littered with abandoned farm buildings and constrained by limited transportation infrastructure to move people and goods around. Well-known for its famous Hellenic, Roman and Arabic cultural infrastructure, as well as for one of the world's more active volcanoes, Mt. Etna, Sicily has significant potential for agritourism development, but requires significantly more infrastructural investment than it currently receives. The group aims to present its findings at the upcoming Conference of Southeastern Geographers and to publish the results in a peer-reviewed journal.
Contact: David Keeling, (270) 745-4555.
WKU Office of Admissions is taking its DiscoverWKU events across the United States this fall.
Sodexo has made a gift commitment to WKU to establish the Sodexo Scholarship Fund to support their employees, as well as their dependents, in the pursuit of higher education at any campus of WKU.
The annual faculty and staff awards were presented Friday morning at WKU's 2017 opening convocation.
Sodexo has made a gift commitment to WKU to establish the Sodexo Scholarship Fund to support their employees, as well as their dependents, in the pursuit of higher education at any campus of WKU.
The annual faculty and staff awards were presented Friday morning at WKU's 2017 opening convocation.
WKU President Timothy C. Caboni outlined the strategic planning process for WKU's future as well as new initiatives being implemented this fall during the annual Faculty Staff Convocation Friday.
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Boutique hotels are just an experience to stay in. They represent opulence, luxury and pure indulgence. As such a popular tourist destination, plenty of city centre Dublin hotels are as described.
The Luxury Hotel Design
The Marker Hotel, along the quays, is a perfect example of the boutique hotel experience. Most places you stay have spacious rooms as you pay premium prices – definitely worth the money though. No matter what room you stay in there are beautiful rooms out of every window of Grand Canal Square and the Docklands to the Wicklow mountains and even out to sea.
Many luxury hotels tend to make their room and suites sanctuaries for their guests where they can relax after a busy day of sight-seeing and just generally exploring.
The Marker luxury hotel is also very aesthetically designed and decorated with modern vibrant colours that tie the neutral more traditional tones together.
Boutique Hotel Benefits
If you're feeling tired, although there are lovely restaurants around, you have the choice to dine in the hotel restaurant which has a relaxing atmosphere. A bar is also within the hotel and another up on the rooftop where you can experience views that go on forever.
As a boutique hotel, The Marker has a spa and wellness centre with a gym. There is an infinity pool, jacuzzi, treatments rooms as there are a list of treatments to choose from. The unique aspect in this boutique hotel is the cocoon chill out space to escape the hustle and bustle of the city centre.
Dublin Hotels Location
Dublin hotels are all about location, location, location! The Marker hotel is situated just down the quays from O'Connell Street, Grafton Street and Temple Bar. They are just a short scenic walk away or just hop on the Luas across the bridge. The luxury hotel is perfect for people attending concerts in the 3 Arena as it can be seen across the Liffey River, the Bord Gais Energy Theatre is just on your doorstep for you to see a show in the evening before dinner and for those sports enthusiasts the Aviva Sports Stadium is in close distance too.
Take the hassle out of getting to the hotel, by booking a limo from the airport and arrive in style. You know that you deserve it!

subset: commoncrawl


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Turquoise Coast (Dalaman) culture
- Turquoise Coast (Dalaman)
- Flights to Turquoise Coast (Dalaman)
- Turquoise Coast (Dalaman) Holidays
- Turquoise Coast (Dalaman) Hotels
Turks are famous for making others welcome, and the majority of people are friendly and courteous to strangers. Almost everywhere, you'll be greeted with "hosgeldiniz" (welcome) and asked a barrage of questions about yourself and your country. This should be treated as genuine curiosity and not an offensive intrusion.
When browsing in a shop, you could well find yourself offered tea. It's not rude to refuse - but in most cases it's probably not a pressure-sell tactic as most people are more than happy to talk to you about where you're from, what you do or whether you're married.
If you're invited to a home (which happens quite a lot, especially if you're out of the main resort areas) you can usually play it by ear. In the average Turkish home you'll be treated as an honoured guest, and if you accept the invitation it's more usual to take pastries, chocolates or flowers than drink. If you visit a Turkish family in a village you should also take your shoes off, and the custom is to kiss the elder's hand and bring it to your forehead.
Things to avoid are kissing and hugging ostentatiously with a member of the opposite sex in public, pointing at someone or blowing your nose. Topless sunbathing is forbidden, and beachwear should be confined to the beach or poolside. Smoking is widely acceptable but prohibited in cinemas, theatres, buses, coaches and taxis.
99% of the Turkish population is Muslim, with the rest split between Orthodox, Gregorian and Protestant Christians, Catholics, Suryani and Jews. Although most of the population is Muslim, Turkey is a secular country and everyone has freedom of religion and beliefs. Nobody can be forced to participate in religious ceremonies or rites against their will, and no blame is attached to anyone because of their beliefs.
Turkey is one of the world's oldest continually inhabited regions, largely because of its location at the intersection of Asia and Europe. The first major empire was that of the Hittites, from the 18th to the 13th century BC. After falling to Alexander the Great in 334 BC, the area was divided into small kingdoms, but succumbed to Rome by the 1st century BC. In AD 324 the Roman Emperor Constantine I chose Constantinople (now Istanbul), as the capital of the Roman Empire.
The rise of the Ottoman Empire after 1299 led to mass conversions to Islam, and created an Islam-based rather than a Turkish-based identity. The Empire interacted with both Eastern and Western cultures throughout its 631-year history, and was among the world's most powerful political entities in the 16th and 17th Centuries. But it fell after the First World War, when the victorious Allied Forces partitioned it through the Treaty of Sèvres.
Soon after, the Turkish War of Independence resulted in the birth of a Turkish state that formally abolished the office of the Sultan. The Treaty of Lausanne of 1923 led to the international recognisation of the sovereignty of the newly formed Republic of Turkey. Mustafa Kemal Ataturk's became the country's first president, and his political, economic, legal and cultural reforms did much to modernise the country.
In 2005, Turkey officially became a candidate country to join the European Union as a full member, having been an associate member since 1964.
The majority of the 73 million population are of Turkish ethnicity. The largest non-Turkic minority group is the Kurds, a distinct ethnic group traditionally concentrated in the South East, and there are also Greeks, Armenians and Jewish communities. However, these groups are well assimilated into Turkish society.
Though Turkish is the sole official language throughout Turkey, broadcasts in local languages and dialects on state media outlets include Arabic, Bosnian, Circassian and Kurdish.
The Turkish population is relatively young, with over a quarter falling within the 0-14 age bracket. Due to a demand for an increased labour force in Post-World War II Europe, many Turkish citizens emigrated to Western Europe (particularly West Germany).
Turquoise Coast (Dalaman) holiday resorts
|Marmaris Holidays
|22 Hotels, Villas + Apartments
|Olu Deniz Holidays
|20 Hotels, Villas + Apartments
|Icmeler Holidays
|9 Hotels, Villas + Apartments
|Hisaronu Holidays
|7 Hotels, Villas + Apartments
|Dalyan Holidays
|4 Hotels, Villas + Apartments
|Ovacik Holidays
|4 Hotels, Villas + Apartments
|Calis Beach Holidays
|3 Hotels, Villas + Apartments
|Turunc Holidays
|3 Hotels, Villas + Apartments
|Fethiye Holidays
|2 Hotels, Villas + Apartments
|Sarigerme Holidays
|1 Hotels, Villas + Apartments


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My favorite private-eye trick is the one I learned about from Errol Morris.
From This Story
You probably know Morris as an Oscar-winning documentary filmmaker. Roger Ebert called his first film, Gates of Heaven, one of "the ten greatest films ever made." With The Thin Blue Line, Morris dramatically freed an innocent man imprisoned on a murder rap. In The Fog of War he extracted a confession from Robert McNamara, getting the tightly buttoned-up technocrat to admit "[we] were behaving as war criminals" for planning the 1945 firebombing of Tokyo, which burned to death 100,000 civilians in a single night.
You may also know that Morris is the author of the recent massive, fascinating book called Believing Is Seeing: Observations on the Mysteries of Photography, which won rave reviews for the way it looks not just into the frame of a photo but behind, beneath it—the way truth is "framed" in every sense of the word.
You may even think, as I do, that Morris has become one of America's most idiosyncratic, prolific and provocative public intellectuals.
But what's less well known about Morris is that he brings to his work the invaluable experience he picked up working as a private eye. And he hasn't given up the private-eye impulse: He's back on the case, two cases actually—two of the most electrifying and controversial cases in the past half century.
Born in suburban Long Island, Morris graduated from the University of Wisconsin. After a stint of cello study in France, he talked his way into the Princeton graduate philosophy seminar of Thomas Kuhn, an icon of postmodernism, the man who coined the term "paradigm shift." It wasn't exactly a meeting of the minds. In fact, it almost cracked Morris' skull, which is what Kuhn seemed to be aiming to do at the climax of an argument when the esteemed philosopher threw an ashtray at Morris' head.
"The Ashtray," Morris' five-part, 20,000-word account of that episode and their philosophical clash over the nature of truth, is a good introduction to the unique kind of writing he's doing now. (Don't miss the section on the obscure Greek philosopher of irrationalism, Hippasus of Metapontum, a digression worthy of Jorge Luis Borges.)
After the ashtray incident, Morris eventually did two stints as a private eye. If there is one subtext to all of Morris' subsequent films and writings, it is the private eye's creed, the anti-postmodernist belief that "the truth is out there." Truth may be elusive, it may even be unknowable, but that doesn't mean, as postmodernists aver, that reality is just a matter of subjective perspectives, that one way of seeing things is just as good as another.
"I'm amazed," Morris said when we spoke recently, "that you still see this nonsense all over the place, that truth is relative, that truth is subjective. People still cling to it." He calls these ideas "repulsive, repugnant. And what's the other word? False."
But I digress (something impossible to avoid in writing about Errol Morris). I wanted to tell you about his private-eye trick, which he learned from a hard-bitten partner.


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Sounds like a tough go today for us so far - me included and I haven't gone running yet. While doing a yoga spinal twist stretch yesterday morning, I managed to rotate one of my low back vertebrae and it is causing my hip and leg muscles to be tightened up and my back to hurt. I got a massage yesterday but it didn't help much. She couldn't budge it although she could feel the abnormality. I've done my yoga workout and am going running to see if it will help sort it out.
Go as long as you can, and then take another step.
Ze - glad you survived - I'm sure you'll try another marathon once the ole memory fades...
Dutchie - what does chia taste like?
and Happy - don't overdo it! I tend to run/ stomp when I'm stressed and sometimes that can aggravate a minor injury. How about a hot bath and glass of red wine/ hot chocolate later...
Just getting through my scheduled runs, working through the weekend. Now nap time before a Saturday night date with the hub.
Happy weekend, A
You're so wise, Ayola. I'll heed your advice.
Imminent Catastrophe
Dutchie - what does chia taste like?
I can answer that--it doesn't taste like anything.
I grind up the chia and flax seed and put it in smoothies. Also on race days as soon as I wake up I have a big drink of sportsdrink with chia mixed in, I think it slows the absorption and doesn't mess with my blood sugar levels as much.
I haven't been "right" lately, just kind of tired and listless and unmotivated. ANyway today's 9 fit right into that theme, it was really not fun and felt really hard. These things come in cycles, hopefully I'll snap out of it soon. I might have a slight touch of flu.
MTA: Crap, I'm behind the bunny too!
"Able to function despite imminent catastrophe"
"To obtain the air that angels breathe you must come to Tahoe"--Mark Twain
"The most common question from potential entrants is 'I do not know if I can do this' to which I usually answer, 'that's the whole point'.--Paul Charteris, Tarawera Ultramarathon RD.
√ Javelina Jundred Jalloween 2015
Cruel Jewel 50 mile May 2016
Western States 100 June 2016
Ze - Great job on the marathon! Sounds like you really gritted it out in the end. You must be so proud of yourself for working through the tough finish. The marathon can definitely be cruel, but it can also be much more fun. A little better prep next time and it can be so much different. Give it a little time and you will be ready to try again.
Happy - Yoga is supposed to make you feel better. I think you might have been doing it wrong . I hope you feel better soon. Going for a run has a way of fixing my back pains.
A and Russ - Just a couple more months and we can get some longer, warmer days. Seems like I'm just getting through my runs right now too.
Space Cadet
Hi everyone! Here's to hoping that all job situations, back stuff, and blahs are resolved soon.
As for me....I'm behind the bunny. The running is improving, but I'm getting xrays on the arm on Tuesday. That will be 3 weeks after the fall. I still can't put pressure on the elbow area without some discomfort. I have full use of the arm and range of motion in the elbow or I would have gone earlier. I have been anti medication for a long time and I've been popping aleve for 2 weeks.
Did I say that I was an RN for 24 years? That might be why I really dislike hospitals/doctors/medicine.
A half mile from the end of my 12-miler today, I got a call from DH saying he'd cut a fingertip off on the table saw and we'd need to go to the ER as soon as I got home. Delightful. Missed my cooldown walk and after run snack, but thankfully he only cut the pad off the middle finger and sliced into the index finger. The bone and nail are intact. All's well than ends well, right? For my run - it went alright. My back hurt a bit towards the end, my muscles were not as loose as I'd like, but not as bad as I feared. It was a lot colder than I expected. There were some icy patches and I skated around a couple times; but I took it easy and am happier for the run.
It's a good thing you got that run in. Maybe it will help you deal with everything else happening today.
Happy: men should not come near something like a table saw. Way too dangerous Glad to hear it turned out better than it sounded.
I was soooo not in the mood for a run this morning and procrastinated my way to 6h30 before finally hopping on the TM. Only to find that my run felt effortless and fun.7 min R @ 9K / 30 sec Wrepeat 3 timesand finish with a sprint:1 min R @ 9K1 min R @ 9.5K1 min R @ 10K1 min R @ 10.5K
Dutchie I go running in the early morning, before my brain figures out what I'm up to.
Run the day, or the day runs you.
Actions determine state of mind - Aristotle
I don't think my treadmill motor will hang on much longer. It kept stopping suddenly tonight - about 10 times every mile. The sudden stops were nearly enough to toss me off the belt a couple times and made me break into a sweat and heart rate shoot up every time.I didn't feel tip-top today anyway and it got to where felt like if I kept running, I'd throw up! I threw in the towel after about 3 miles.
Now we just have to figure out how to get the motor out of the TM - with DH's mangled fingers and my help. The motor weighs 35 lbs! My local machine shop says they can fix it for about $100 which is not too bad I thought since a new motor is about $400.
The good news is my trail running friend has resurfaced and we are heading for the hills on Saturday morning!!!!
I was soooo not in the mood for a run this morning and procrastinated my way to 6h30 before finally hopping on the TM. Only to find that my run felt effortless and fun.
I was soooo not in the mood for a run this morning and procrastinated my way to 6h30 before finally hopping on the TM. Only to find that my run felt effortless and fun.
I realize it sounds whiny but I'm still in a funk. Ran 6 in frigid Chicago but it really felt much harder than it should have, then was in El Paso and there was NOWHERE to run. Usually I can find a place but it's at the airport and there are no sidewalks or shoulders, I went about a half mile and gave up. I'm still not right. Meh.
I'm still in a funk. I'm still not right. Meh.
I'm still in a funk. I'm still not right. Meh.
Well that's no fun! Has this ever happened to you before? Is it like burn-out? Are you "cooked?" Feel pressured by goals? Sounds like you may feel "pushed" and are not happy about it. Maybe ultrarunners need longer bigger breaks within their year. It has to be a huge mental effort to run 100 miles! Maybe only do runs that are fun like doggie-runs or especially scenic runs. Maybe go out every day, but only for short runs. Why you were drawn to running in the first place? Think about that to rekindle your interest? Forcing yourself to be disciplined to run might backfire, but on the other hand it might not - you might fall back into the habit. I am rambling and likely not being helpful. Hope you and your avatar are right side up soon.
Dutchie - Nice run. good to see you getting back in the groove.
Russ - I'm sure you will turn the corner soon.
Not much going on here. Just trying to get my weekly mileage up where it should be. I'm struggling to have enough hours in the week to get my runs in. The long runs are going well it's just the runs during the week (after work) that are eluding me.
The Crap Whisperer
I went through a phase like that last year - from April to July(ish). I stopped logging my miles and that actually helped. I still ran every day but I dropped any sort of long run and ran as much as I felt like and at whatever pace. I still wore my Garmin so when I was ready to get back to something more structured I was able to upload all my miles and know where I was for the year. I don't know if that would help you or make you nuts but I helped me to run for the sake of running and not worry about anything else. somtimes I miss my days of no logging
Being the best tiny spec that I can be!
You are absolutely right, I am flirting with burnout. And you are, as always, being quite helpful. Thing is, I foresaw this in December and planned a recovery period, didn't run much for the last few weeks, but apparently it wasn't enough, combined with the flu (DW had a brief but intense case and I think I had a mild case).
The run-up to my 100 last year was really taxing, and a huge emotional investment. I was going full-tilt for 10 months, then I had the BQ race in December. So I knew I needed some rest, both physical and emotional.
Anyway, today was something of a comeback. I drove up to Chickamauga National Military Park, probably my very favorite road place to run, and got in a nice 26.2 mile run. A decisive Civil War battle took place there in 1863, That place is so beautiful, with the statues and monuments and cannons and such. I didn't plan on doing exactly 26.2 but that's what Garmin said as I ran up to my car. Sure, I was tired, and legs were somewhat fatigued, but I was amazed by how good I felt (considering) at the end. Tomorrow I will volunteer at a race that I ran last year and actually won! So I am surrendering my title but the RD is a really cool guy and I'm glad to be helping him out.


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Hey there, time traveller!
This article was published 30/11/2012 (1722 days ago), so information in it may no longer be current.
JUST as quickly as hockey types -- players, fans and media alike -- got to know the names of the two mediators who tried to help salvage the NHL season this week, they vanished from the negotiating table.
So long Scot L. Beckenbaugh and John Sweeney. We hardly knew ye.
And so you'll have to excuse many members of the NHL Players' Association and the game's observers if they have their doubts about the next concept being tossed around by the NHL to get a deal done:
Having owners and players sit down together without the heavy hitters, like commissioner Gary Bettman and NHLPA executive director Donald Fehr, in the room.
"It could be a good idea," said Winnipeg Jets captain Andrew Ladd Friday. "There always seems to be a catch with every idea the owners have. If it's something where we could get all 30 owners in the same room with representatives from each team and talk, just so they know where we're sitting and where everybody stands then, yeah, it could be positive.
"But if they want to pick the owners and players that get to go into that meeting, it's just another idea that has a catch and sounds really good to the media and fans at first. And once you look into it more and more, it's kind of a hoax. It's got to be done the right way.
"If it's still the same guys from their end talking... if it's (Boston Bruins' owner) Jeremy Jacobs in there spewing his stuff, I don't think it's going to move this process forward."
And so as another week has gone by with no resolution, the NHL is apparently waiting to hear back from the players' association as to how to set up this next meeting.
The optimists point to how New England Patriots' owner Robert Kraft was able to help broker a deal for the NFL.
The cynics call this latest move a gimmick and a PR ploy.
And as former NHLer-turned-agent Brian Lawton said via his Twitter account Friday: 'If the parties can't come to agreement on who is going to meet then yes hockey is in more jeopardy than any of us even imagine.'
"It would be nice to sit down and talk and see where they're at and see what they understand and know and see where each side is coming from and try to sort it out like the mature men we all are," said Jim Slater. "That'd be the best thing... talking to these owners that really care about hockey and getting it back on the ice. I think there's a lot of them out there that are like that."
Asked what it would be like to sit across the table from Jets' owner Mark Chipman -- a popular owner the players refer as "Chipper" -- Slater said:
"Everybody gets along with Chipper very well, he's very easy to talk to. I'm sure there's a lot of owners like that who are out there and it would be nice to see where they're at.
"That's the best thing... talking to these owners that really care about hockey and getting it back on the ice."
The lockout is now into its 77th day and on Friday the players missed their fourth paycheque of the fall. The NHL has cancelled games through Dec. 14 as well as the Winter Classic and NHL All-Star weekend scheduled for Columbus in late January.
And if this latest attempt doesn't work, decertification may be the next move by the NHLPA. That would see the players revoke the NHLPA's authority to bargain for them and then allow them to sue the league for antitrust violations.
That's when things could really get ugly.
"We're exploring all options," said Ladd. "They've kind of backed us into a corner where we don't have much leverage. They're just trying to wait us out and miss paycheques and see if we're going to fold. But that's not a very good strategy on their part because I don't think we're going to fold."
firstname.lastname@example.com Twitter: @WFPEdTait


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Flames NewsFlames Home > News
No. 2 seed Liberty Advances to BSC Semifinals with First-Half Goal
The No. 2 seed Liberty women's soccer team is heading to the semifinals of the 2013 Big South Women's Soccer Championship presented by Musco Lighting, after defeating Presbyterian College, 1-0, in a quarterfinal matchup, Sunday afternoon, at Osborne Stadium.
With tournament play heading to Conway, S.C. for the final two rounds, Liberty (14-5-1, 8-2-1 Big South) now meets No. 6 seed High Point in a semifinal matchup, Friday at 7 p.m. The Panthers defeated No. 3 seed Longwood, Saturday, 3-1. Friday's semifinals will stream live on the Big South Network.
PC (9-9, 6-5 Big South) concludes the year with its first nine-win season since 2003. The team's 24 goals scored are the most since 2007. PC's 21 goals allowed are also the fewest in the six-year span.
Crystal Elmers posted the game-winning goal for the Lady Flames in the 43rd minute, receiving a cross in front of the goal from Brittany Aanderud. Elmers now leads the team with six goals on the season, while Aanderud's third straight assist in as many games gives her 11 for her career. The mark now ties her with Madison Short (2009-11) and Aimee Luurtsema (2008-11) for the third most in program history.
Liberty goalkeeper Holly Van Noord finished with two saves on the day, notching her 13th shutout to extend her single-season program record. Jordan Broadway played the first half in between the pipes for PC, making one save. Sydney Fontenot came in for the final 45 minutes, making five stops.
Liberty outshot PC on the afternoon, 20-3, and held a 5-0 advantage on corner kicks.
Midfielder Madison Kauzlarich nearly put Liberty on the board early in the first period, banking a shot off the cross bar in the fourth minute. Later in the 21st minute, PC midfielder Kelly Kozera sent a shot at the Liberty net, but Van Noord corralled the attempt to keep the contest scoreless.
The PC offense forced Van Noord to react quickly once again in the 42nd minute. Forward Sara Simpson broke away from the Liberty defense and fired a shot at the Liberty goal. Van Noord swatted the ball down and recovered for her second save of the afternoon.
Liberty then responded with its lone goal just before halftime. Dribbling inside the 18-yard box, Aanderud placed the ball directly in front of the goal frame, allowing Elmers to run onto it and chip it into the back of the net, giving Liberty a 1-0 advantage.
While Liberty outshot PC, 9-0, in the second half, Fontenot managed to thwart all five of the Lady Flames' attempts on goal. Midway through the 87th minute, Swentik ricocheted a shot off the crossbar. Fontenot collected the ball 21 seconds later off an Alanna Dunkle shot for her fifth and final save of the contest, ultimately setting up the 1-0 final.


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As someone used to parametric modelling in Inventor, rhino feels like a significant step backwards. Sure it's got way more useful surface and spline modelling tools, but it just feels klunky and limited. For instance, fillets need to be done in a specific order (large to small) in order to not break your model! Once a small fillet is applied, you'd need to revert to a save prior to the small fillet in order to apply a larger fillet to a touching edge. Lunacy :-(
However, if you model (or import) geometry, and apply interesting things in Grasshopper, there is significant power. Grasshopper has blown my mind. It's not perfect, but it's incredibly powerful, and fairly fast to use. I wish there was better documentation on all the various functions. Perhaps one day soon there will be.
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This is a repost in light of the recent news that the news media finally picked up on the fact that adult stem cells are cutting the butter and embryonic stem cells are still only a load of hype… er, tripe.
Anyway, here's what we knew 3 years ago:
In case you didn't know: adult stem cells have been used for years to successfully treat a wide range of conditions successfully. Private companies have seen the success and have poured large amounts of money into programs exploring the benefits of stem cells derived from adult adipose (fat) tissue, marrow, and other sources.
So what's all the hubbub over skin cells? And why are embryonic stem cells such a hot topic?
In a chokingly self-important article which seems to further support Dennis Prager's assertion that liberals can go their whole lives without meeting a conservative, Time Magazine claims the recent discoveries about the ability of skin-derived stem cells to differentiate (grow into different organs, technically called pluripotency) will not benefit the GOP. Come again? What does good science have to do with politics? And do you even know the history of the issue? I thought not, the MSM conveniently does not read any medical journals unless their tipped off by some juicy tidbit they may use to further their own radical agenda.
The article's author, Michael Kinsley, says he has Parkinsons, a disease for which stem cells hold great potential in curing. Current Parkinsons treatments using embryonic stem cells turns the patients into shaking, slobbering babes incapable of the most basic self-care. Embryonic stem cells have a more direct and immediate potential for pluripotency as that is what they do: they turn into cells for each organ and tissue in the body. Unfortunately their growth is uncontrollable right now and they end up turning effectively into tumors in the brains of those who are injected with them.
On top of this, the ethical and moral issues involving the harvesting of human embryos are staggering and I fall in with those myriad souls who fight to stop the harvesting and destruction of human life with the goal of bettering human life. How far removed are we from Nazi Germany, when diabolical doctors of death practiced upon innocents by the millions to further the happiness of the rest of humanity? Is that a worthwhile trade?
In fact, to date there has not been a single successful treatment of any condition or disease using stem cells harvested from embryos.
Private sector investment has shunned embryonic stem cell lines, which means the only group which can be coerced into paying for these death-dealers research projects is… us. The government largess is available to any who crow loud and long enough, and it comes from yours and my pocket books and paychecks.
Private sector research has all gone towards adult stem cell research which offers very potent benefits over embryonic stem cells.
- Adult stem cells suffer no chance of rejection from their host. Adult stem cells are collected from the person they will be used on, meaning the organs grown from them carry the exact biological and genetic "fingerprint" of the rest of the body, there is zero chance of rejection of these treatments.
- Adult stem cells are given voluntarily as part of treatment. There is no moral or ethical morass involved in the collection of the these cells.
- Adult stem cells can differentiate under controlled conditions. Unlike embryonic stem cells, which differentiate wildly and which we are currently unable to control, adult stem cells pluripotency can be controlled in application with greater reliability.
So we have an issue where the successful treatment and therefore all the private money has gone in one direction, but a few stubborn souls insist on using disinformation and outright lies to promote a morally reprehensible treatment system which would have been likely looked upon with distaste by most of the Nazi death doctors in hopes of getting us to pay for a treatment process with no current success and little promise.
"If human embryonic stem cell research does not make you at least a little bit uncomfortable, you have not thought about it enough." ~James A. Thomson
Hugh Hewitt references Charles Krauthammer's article on the issue. Bush was right, technology vindicates morality:
Even a scientist who cares not a whit about the morality of embryo destruction will adopt this technique because it is so simple and powerful. The embryonic stem cell debate is over.
Which allows a bit of reflection on the storm that has raged ever since the August 2001 announcement of President Bush's stem cell policy. The verdict is clear: Rarely has a president — so vilified for a moral stance — been so thoroughly vindicated.
Why? Precisely because he took a moral stance. Precisely because, as Thomson puts it, Bush was made "a little bit uncomfortable" by the implications of embryonic experimentation. Precisely because he therefore decided that some moral line had to be drawn.
Related articles by Zemanta
- STEM CELL UPDATE: Great news: "Researchers at the Children's Hospital in Boston have figured out h… (pajamasmedia.com)
- Great Stem Cell News (reason.com)
- Johnson opposes funding for embryonic stem cells (seattletimes.nwsource.com)
- Non-Embryonic Stem Cells Developed From Skin Cells (science.slashdot.org)
- You: Scientists overcome hurdles to stem cell alternatives (washingtonpost.com)
- Why Are Some Scientists Obsessed with ESC Research? (thebibleistheotherside.wordpress.com)
- Scientists overcome hurdles to stem-cell alternatives (seattletimes.nwsource.com)


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Just beyond the crack of noon.
Rangers close out their four-game homestand (1-2). They go to Pittsburgh's new house tomorrow.
Henrik Lundqvist remains out with that flu/head cold. Martin Biron, who played so well on Thursday, gets the start in goal. Derek Boogaard is back in the lineup. Todd White is prucha'd.
(Special mention of Prucha with Tom Renney in the building; Here's the link to the always-hilarious Tom Renney Line Generator.)


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de Alan and Natasha Brough
Acerca del libro
A collection of poems by Alan Brough, put together by his family in the book he never got the chance to create or finish.
A mixture of poems about the Penrith area, local people, friends, animals and poems about life in general. Also included in the book are the comical Cumberland Tom postcards.
It was always his intention to put together a book of 100 poems and also to write his life story, which he was going to call THE PRICE OF A LION. The loss of his lions hurt him so much that he could never bring himself to create a poem about them. The loss of his horses hurt him so much that we have to go on without him.
All profits made from the sale of this book will go entirely towards the upkeep of his beloved horses.
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Dog-friendly Ballantrae, 3 People & Rural
Situated on a working dairy farm, these two semi-detached holiday cottages can be booked together to sleep 10 in total. Boasting spectacular views of Arran, Ailsa Craig, Mull of Kintyre and the south Ayrshire coast, and are a mere 500 yards to the beach.
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A fireman with his dog on the picket line at Euston London Fire Brigade station house in London. Firefighters and Fire Service staff across England and Wales striked on Wednesday over pensions, with the threat of further action if the dispute is not resolved.
© The Financial Times Ltd 2016 FT and 'Financial Times' are trademarks of The Financial Times Ltd.


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Stop in to see what the library has to offer for you while on the go. This program will focus on the use of smartphones to access library resources. See how to download e-books and audio books directly to your phone without a computer with MyMediaMall's app. Also, see how to access the library catalog and renew books with the LibraryAnywhere app. For those without smartphones, we also have a reference service where you can ask your questions with text messages. The program will be on Monday, October 10 from 7-8 P.M. - MA The program is canceled due to low number of sign ups.
The program is FREE and open to the public. See Adult Services to sign up or call 630-260-1550 for any questions or register online at www.glensidepld.org.


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SAFETY IS THE MOST IMPORTANT THING FOR A PERSON. SAFETY AND LOVE. SECURING SAFETY IS THE STRONGEST INSTINCT. That is also valid for animals as well. Animals live in a constant alertness, all cats, squirrels, lions, all animals live in restless mood. This is an instinct given to humans by God as well. Prophet Abraham (pbuh) prays to God saying; "´My Lord! Make this land a place of safety". "When Ibrahim said, ´My Lord! Make this land a place of safety and keep me and my sons from worshipping idols." (Surah Ibraham, 35) That is the first thing he asks for. For instance God says; "the city that is safe," for Mecca. "You were wandering around safely," says God. That for instance is a characteristic of the Heaven; it is an abode of safety. There is no risk in it. "My Lord! Make this land a place of safety" The abjad calculation gives the date 2011.
Surat Az-Zukhruf, verse 57
"When an example is made of the son of Maryam your people laugh uproariously."
When an example made of the son of Maryam, your people," these people are Muslims, "laugh uproariously," God says. They are making fun -may God forbid- of the Jesus Messiah. And God shows us that He will take revenge. God says that making fun of Jesus Messiah draws God's wrath and that He will take revenge. That is what they still keep saying- may God forbid. "Would Jesus Messiah rise from the dead?" they say, may God forbid. Let me see if you can say this in the Hereafter. Let me see if you can say that to Jesus Messiah when he comes.
Surat Al-Maidah, verse 82
"..You will find the people most affectionate to believers are those who say, ´We are Christians.´ That is because some of them are priests and monks and because they are not arrogant."
"You will find the people most affectionate to believers are those who say, ´We are Christians." Now see what God says? Love. Do you know what this means? When you look into the verses you do so by looking at the verses from one side to the other. "You will find the people most affectionate to believers" What is the meaning of this verse? It means you should love them as well. That is what the verse actually means. Now if someone loves you and you do not love that person back, you cannot talk about love. What does this mean then? It means that "you should love them even more." That is the meaning of the verse. "There should be affection, love all around," God says in the verse. We should not look at the verses single sidedly. For instance; "That is bad." What does this mean? It means something contrary to that is good. That is what it means.2013-06-13 23:39:18


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Stores »
Extra cute with colorful flowers the ultimate chic deck.
seductive skateboard deck with chics kissing. HOT!!!!! I just want to hang it on my wall.
We are a community of shoppers sharing our best finds from across the web.
© 2017 ThisNext, Inc. ThisNext is a member of BUZZMEDIA Entertainment, a division of BUZZMEDIA.


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When you don't know a picture has been taken of you until you see it uploaded by someone else on facebook. Usually results in an embarassing picture getting into the public's viewership, or it can be a normal, innocent picture.
I got wasted and started getting rowdy with this hogbeast, but I didn't think anyone saw and I got away with it. Unfortunately I got a facebook surprise when I saw jen uploaded pics from that party and it had some ebarassing photos
by oogens September 06, 2007
The Urban Dictionary Mug
One side has the word, one side has the definition. Microwave and dishwasher safe. Lotsa space for your liquids.Buy the mug


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working smartphone snes emulator(s)! and avalon5's new smartsnes
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Bobby Valentine to the Marlins?
Former Mets manager Bobby Valentine will fly down to Miami today to meet with the Marlins' brass about the opening for their manager position after they fired Fredi Gonzalez earlier this week. It is widely speculated that Gonzalez will take over as the Braves skipper after this season since Bobby… Read More →


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Heat oil in a saucepan and sauté onion for 1 to 2 minutes. Add millet and sauté 2 to 3 minutes. Add water, corn, carrots and sea salt. Cover, bring to a boil and simmer on low for 30 to 35 minutes. Place in a serving dish. Sprinkle equal amounts of Eden Shiso Sprinkle, Eden Dulse Flakes, Eden Shake or Eden Gomasio and parsley over each serving.
Per serving - 317 calories, 6 gram fat (18% calories from fat), 9 gram protein, 57 gram carbohydrate, 7 gram fiber, 0 milligram cholesterol, 60 milligram sodium


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Happ's hot streak comes to end in rough outing
Struggling offense, defensive miscues contribute to loss
SEATTLE -- The Blue Jays are still very much in the mix for a spot in the postseason but they haven't exactly done themselves any favors over the past two weeks.
Toronto started August in prime position to take a stranglehold over the second American League Wild Card. Instead of moving away from the pack, though, the Blue Jays have started to fall behind and a lack of offense is the main reason.
The problems continued Tuesday night as the lineup once again struggled while J.A. Happ surrendered five runs over six innings in a 6-3 loss to the Mariners at Safeco Field.
"You have to slug in this business," Blue Jays manager John Gibbons said. "In the American League, that's what you do and we're not doing that. If everything's not perfect on the pitching staff, you're not throwing those games when you're not shutting them down, it makes it tough."
This is the first time in more than two decades the Blue Jays are playing meaningful games in August but the team's response so far has not been positive. Toronto is 3-8 this month and has been outscored 58-30 over that same span.
The Blue Jays can only hope that a return to health will lead to an increase in runs. The first step happened Tuesday night when Adam Lind was activated off the disabled list and Edwin Encarnacion is expected to follow suit later this week.
The one consolation from the recent struggles is that the Blue Jays still find themselves within striking distance of the second Wild Card spot. With Tuesday's loss, Toronto is two games back while Seattle moved into a tie with the Tigers. That's an attainable deficit but this is also a team that has been very inconsistent all season and it can't allow the current dry spell to last much longer.
"People say that's just baseball," Happ said of the ups and downs. "I know you guys don't want to hear it, and I don't want to say it, but it does seem to be the way it goes sometimes. We have to get back up and try to salvage this thing. Try to get this one tomorrow and try to start this thing going up."
Happ entered the game riding one of the best streaks of his career. He had a 1.71 ERA in four starts since the All-Star break and continued to exceed expectations by solidifying the back end of Toronto's rotation. There was a strong chance for an eventual regression to the mean and that happened vs. the Mariners.
The 31-year-old retired the first seven batters but his defense let him down in the third. With two outs, Colby Rasmus had a single to center field bounce away from him. Logan Morrison scored all the way from first base as Seattle evened the score at one.
Seattled added another run in the fourth on a solo homer by Kyle Seager and the outing got away from him in the fifth. Two of the first three batters reached base and Dustin Ackley later delivered the big blow with a two-run single that came with two outs.
Happ was charged with four of the five runs on seven hits and one walk over six innings. It was the most runs Happ surrendered in a start since he took the loss in a game vs the Angels on July 7.
"This is probably going to sound weird, but I'll take my chances with the way I threw the ball tonight, any day of the week," Happ said. "The results weren't there, so that's obviously frustrating, every game is big, but you can't get too down on this. I felt good, I felt like I was making pitches."
The lone run Toronto managed to score off right-handed starter Chris Young came in the first inning when No. 2 hitter Melky Cabrera hit an RBI double to right-center field.
Young recovered from the early mistake by facing two batters over the minimum for the rest of his outing. He allowed two hits and two walks with three strikeouts over six innings. Toronto did manage to put together a rally in the eighth but the damage had already been done.
"You never want to start the game off by walking the leadoff batter," Young said. "It's a tough lineup. Those guys can swing it. They've got some of the best hitters in the game. I dug us a little hole early, but had complete confidence the guys would pick me up. I just tried to limit the damage, get back in the dugout and the guys took over from there."
Gregor Chisholm is a reporter for MLB.com. Read his blog, North of the Border, and follow him on Twitter @gregorMLB. This story was not subject to the approval of Major League Baseball or its clubs.


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Last week, my girlie Marie Denee of The Curvy Fashionista invited me to a pre-Espy's Softcup retreat at Bliss Spa located in the W Hotel in Hollywood.
There were lots of celebs and athletes hanging around getting their choice of spa treatments. Just to name a few actress Gabrielle Union, sisters Vanessa and Angela Simmons, ESPN's Erin Andrews, and hottie actor Jesse Williams.
As I was getting my manicure, I happened to be sitting next to the beautiful actres Gabrielle Union. We were all having a discussion about Softcup. If you don't know, Softcup it's the "no strings attached" feminine product. We were just getting tips on how to use it and the benefits of it. Believe me you have to check it out.
After my manicure, I munched on treats from the Little Next Door brasserie. The hummus is soooo yummy! Then I had a few cocktails while I was waiting for my amazing aromatherapy swedish massage.
And I can't forget about my first ever oxygen facial. OK, it was my first facial ever and it was to…die…for.
I didn't even know there was a Bliss Spa located that close to me and now I want to go ALL the time. Sometimes we need a little or a lot of pampering. Thanks to all the staff who were amazingly friendly! This is spa event I'll never forget!
Sorry, I don't have any pics of my outfit. But, I was wearing a coral SWAK tank and Torrid skinny jeans.


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Home > Baptist Hospice House and Center for Good Grief
When a life-limiting illness is no longer manageable at home, the Baptist Reynolds Hospice House can provide much-needed comfort and support to patients and their loved ones. The Hospice House is located on the campus of Baptist Memorial Hospital-Collierville. The residence is located in a tranquil, wooded setting and features a home-like environment with 24 private rooms. Offering a full-continuum of care, our specially-trained staff is available around the clock and is dedicated to improving the quality of life of our residents.
To be eligible for care at Baptist Reynolds Hospice House, one must:
Residential care—full-time residence at the Hospice House—is covered by Medicare and most private insurance plans; however, room and board charges are not covered by these plans. Daily standard room and board charges are the responsibility of the patient and/or family.
Inpatient care may be required for intense monitoring and treatment for pain control or other symptom management which cannot be provided in a normal home-like setting. This level of care is typically covered by Medicare and other insurance plans.
Those staying at Baptist Reynolds Hospice House will have unparalleled access to our unique combination of medical, emotional, and spiritual care. Physicians, nurses, certified nursing assistants, social workers, grief counselors, chaplains, and volunteers work as a team for the patient and their loved ones.
Medications which are related to the patient's hospice diagnosis are covered by Medicare and most private insurance plans.
The Kemmons Wilson Family Center for Good Grief is a comprehensive bereavement center, located adjacent to the Hospice House. Its mission is to provide a safe environment for children, teens, and adults to explore and express their feelings related to the death of a loved one and learn to thrive in a world without that special person.
Services include grief counseling, grief support groups and grief camp programs for children, teens and adults.
Bereavement services are free of charge and are made possible through individual donations and grants funded by the Baptist Memorial Health Care Foundation, The Kemmons Wilson Family, and various organizations and individuals.
The Baptist Reynolds Hospice House and Kemmons Wilson Family Center for Good Grief is made possible by contributions from the community, an endowment fund from the Baptist Memorial Health Care Foundation and fundraising efforts, such as the annual Art of Caring event. If you would like more information about the work of the Foundation or wish to make a contribution to the hospice fund, please call (901) 227-7123 or (800) 895-4483, or you may make a secure online donation at BMH Giving. Thank you for your generous support.
For more information about Baptist Reynolds Hospice House please call 901-861-5700.
Address1520 West Poplar AveCollierville, TN 38017
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The Application of Breast MRI in Staging and Screening for Breast Cancer
The Application of Breast MRI in Staging and Screening for Breast Cancer
Contrast-enhanced breast magnetic resonance imaging (MRI) is a relatively new but increasingly used modality for the detection of breast cancer. MRI has demonstrated utility in identifying additional tumor foci and extent of disease in patients with known breast cancer. This is especially useful with invasive lobular carcinoma, which is difficult to evaluate on mammography. MRI has been found to identify the primary tumor in 70% to 86% of cases of occult breast cancer. Contrastenhanced breast MRI has shown some usefulness in the detection of residual cancer following surgery but is limited by postoperative changes. In patients who have undergone neoadjuvant chemotherapy, breast MRI is most accurate in those patients in whom there is little or no response to chemotherapy. The use of contrast-enhanced breast MRI for breast cancer screening is controversial. It has only been used in a few small studies of high-risk patients. The limitations of breast MRI include uptake in benign lesions and normal tissue, sensitivity for ductal carcinoma in situ, cost, and availability. This paper will discuss the uses, benefits, and limitations of contrast-enhanced breast MRI in the staging and screening of breast cancer.
Contrast-enhanced breast magnetic resonance imaging (MRI) is a relatively new modality for the detection of breast cancer, but its use has been increasing exponentially with the development of new techniques and applications. This paper will discuss the uses, benefits, and limitations of contrast-enhanced breast MRI in the staging and screening of breast cancer.
Gadolinium-diethylenetriamine penta-acetic acid (DTPA) contrastenhanced MRI to evaluate breast cancer was first described independently by two groups in 1989.[1,2] Since those first studies, a large amount of data has been accumulated, but there is no consensus as to technique, interpretation criteria, and indications for use (as there is for mammography and sonography). Breast MRI does offer a highly sensitive imaging modality for breast cancer without radiation, but MRI is not a replacement for mammography or breast ultrasound. It is, like ultrasound, another problem- solving tool for the detection of breast cancer.
Breast MRI involves evaluation of the breast or breasts prior to and after the administration of gadolinium- DTPA intravenous contrast. Images of the breast(s) are obtained immediately after the administration of the contrast bolus and repeated three to five times over several minutes. This results in multiple images of each slice of breast tissue, demonstrating the change in contrast enhancement over time. The presence, morphology, and pattern of contrast enhancement are evaluated for suspicious lesion(s).
Contrast-enhanced breast MRI is based on the production of angiogenic substances by tumors that result in the development of new vessels to supply the tumor. These new vessels are abnormal. They are permeable, have arterial-to-venous shunting, and are not associated with the concomitant production of lymphatics.[3] This neovasuclarity results in rapid enhancement of the tumor relative to the normal issue. The sensitivity of contrast-enhanced MRI in detecting breast cancer is high, ranging from 88% to 100%,[1,2,4] but the specificity ranges from 37% to 96%.[1,2,4-6] This variable specificity is a limitation in the use of breast MRI.
Imaging of breast implants for rupture or free silicone was the first widely accepted indication for breast MRI. Evaluation of breast cancer patients for tumor extent, occult disease, and posttreatment planning are becoming common applications. Additional uses of breast MRI to further assist in the assessment of questionable mammographic or physical examination findings is emerging. Contrast-enhanced MRI for breast cancer screening is controversial.
Breast Cancer Staging With Contrast-Enhanced MRI
Multifocal or multicentric disease has been demonstrated in 31% of patients with known breast cancer.[7] Residual breast cancer at the lumpeclumpectomy site can result in recurrence. Therefore, successful treatment depends on accurate presurgical knowledge of the extent of the disease. Mammography and sonography can often locate the primary tumor, but small, multifocal, or multicentric lesions may be missed unless they are actively sought out.
In a study comparing imaging modalities for assessing breast cancer, mammography found 90% of the index tumors, ultrasound found 85%, and MRI found 98%. Tumor size was underestimated by 14% on mammography and by 18% on ultrasound, but the size of the tumor at histology was not significantly different from that seen on MRI.[8] In patients with a known primary tumor, breast MRI can better establish the extent of the disease (Figure 1). Contrast-enhanced breast MRI identified additional malignant foci in the ipsilateral breast in 22% to 34% of patients with known breast cancer.[6,7] Mammographically occult synchronous tumors in the contralateral breast were found in 5% of patients.[9]
Invasive Lobular Carcinoma
MRI is especially useful in evaluating invasive lobular carcinoma, as it is difficult to identify on mammography. It has been reported that 19% of patients with invasive lobular carcinoma have no mammographic findings.[ 10] This may be due to the growth pattern of invasive lobular carcinoma, which has been classically described as groups of malignant cells in a one- to two-cell-thick linear arrangement. This neoplasm does not form a sheet of tumor cells, so there is no tumor mass.
Often, what is seen on mammography is the body's desmoplastic response to the tumor. The most common mammographic appearance is an asymmetry or ill-defined mass that is the same density as the surrounding breast tissue and is hard to differentiate from the normal parenchyma.[10] Sonography can identify almost 90% of cases of invasive lobular carcinoma,[11] but often, ultrasound is only done when a mammographic or clinical abnormality is present in the area. Invasive lobular carcinoma is more likely to be multicentric and bilateral than ductal carcinoma. These factors combine to make diagnosis and treatment of invasive lobular carcinoma difficult.
MRI is useful in evaluating patients with invasive lobular carcinoma. MRI has identified additional tumor foci in 22% to 40% of patients with known invasive lobular carcinoma[ 12,13] and contralateral foci in 9% of patients.[12] Although MRI has been seen to be sensitive for lobular carcinoma, reports have indicated false-negative MRI findings. A few cases have been reported in which there is little or no contrast enhancement.[8,14]
The enhancement pattern seen in invasive lobular carcinoma may also make detection difficult. A discrete mass was found with contrast-enhanced breast MRI in 30% to 56% of invasive lobular carcinoma cases, and 39% to 61% demonstrated multifocal or regional enhancement.[13,15] This regional enhancement can be confused with fibrocystic or glandular uptake and may be underidentified. The extent of disease on pathology has been seen to correlate with the MRI findings in 85% of patients.[14] Due to MRI findings, 50% of patients with invasive lobular carcinoma undergoing preoperative breast MRI had a change in their surgical management.[ 16] MRI can be a useful addition to the evaluation of invasive lobular carcinoma and should be considered for preoperative evaluation of the disease (Figure 2).
Need for Cautious Interpretation
The identification of more extensive disease can determine if the patient is a candidate for mastectomy or breast-conservation therapy. Of the patients with additional foci, 13% to 21% had their treatment changed to mastectomy or to lumpectomy with wider local excision because of MRI findings.[7,16] Breast MRI can also determine chest wall invasion better than mammography or ultrasound. Tumor involvement of the chest wall, regardless of primary tumor size, changes the disease stage to IIIB.
However, prudence should be used with the application of breast MRI in evaluating breast cancer patients. There is overlap of contrast enhancement in benign and malignant breast processes on MRI, and 4% to 21% of the patients undergoing preoperative breast MRI have false-positive findings necessitating additional biopsy and worry.[7,9,16,17] The patient needs to realize that there is a possibility of false-positive and falsenegative findings with MRI. Physicians should help patients understand what this may mean in regard to their treatment plan.
The high sensitivity of contrastenhanced breast MRI has created the impression that it is the gold standard for evaluation of breast cancer. The assumption is made that any enhancing area on MRI is a carcinoma. It is important to recognize that 29% to 80% of lesions with suspicious enhancement on MRI are benign on histology.[ 7,9,16,17] Some patients have become so concerned by the presence of an abnormality on breast MRI that they go directly to prophylactic mastectomy, at which point no malignancy may be found in the specimen.[ 9,17] Liberman et al found that 9% of patients with a suspicious MRI finding underwent prophylactic contralateral mastectomy, compared to 3% with no findings.[9]
Occult Breast Cancers
Axillary metastasis without clinical or mammographic evidence of the primary has been reported to occur in less than 1% of cases of breast cancer.[ 18] If the primary tumor cannot be found, the patient often undergoes modified radical mastectomy followed by chemotherapy.[18,19] Many surgeons are hesitant to perform a mastectomy without demonstrated breast malignancy. No evidence of carcinoma is found in one-third of these "blind" mastectomy specimens.[18]
Although the number of patients is small, studies of occult breast cancer have found that 70% to 86% of the primary tumors can be identified on contrast-enhanced breast MRI.[19,20] The majority of the cancers appeared as focal-enhancing lesions with spiculated or irregular borders. False-positive findings included patients with no tumor found at pathology or cancer found in areas of the breast that were not the same as the enhancing lesion.[20] Finding the primary tumor allowed 37% to 41% of these women to undergo breast-conservation therapy.[ 19,20] Tumor was found in 81% of the specimens in patients with MRI findings.[19] The lack of an enhancing lesion on MRI changed the treatment plan to axillary lymph node dissection and breast radiation therapy in a few of the study cases.[19]
Not all lesions seen on MRI are malignant, and biopsy is necessary before a final treatment course can be determined. Generally, once the lesion is found, the mammograms are reassessed and an ultrasound is performed. If the lesion is seen on ultrasound, then a faster and less expensive ultrasound-guided biopsy can be performed. Otherwise, MRI-directed biopsy can be performed at facilities with the appropriate equipment.
Follow-up Post-Neoadjuvant Chemotherapy
Neoadjuvant chemotherapy is given to patients after the diagnosis of malignancy has been made but prior to definitive surgical treatment, to decrease the size of the tumor. Recurrence rates and positive margins have been reported to be similar to those seen in patients with early-stage cancers.[ 21] Therefore, for a woman with advanced disease, neoadjuvant chemotherapy can enable the use of breast-conservation therapy as an alternative to mastectomy without a difference in survival.
The extent of response to chemotherapy and amount of residual tumor determines the treatment options in this setting. Delineating the response poses a clinical challenge. Traditionally, palpation, mammography, and sonography have been used, but edema and necrosis at the tumor site may hinder measurement of the tumor's true size. Clinical breast exam has been found to underestimate residual disease. In one study, the average tumor size after neoadjuvant chemotherapy was 2.2 cm on clinical breast exam and 3.0 cm on final pathology[22]; 63% of patients who were thought to have had a complete response to chemotherapy on clinical exam had residual tumor on final pathology.[23]
Mammography does not show much better results. Vinnicombe et al found that five of eight patients with complete response to chemotherapy on mammography had residual tumor at excision.[24] Mammographic assessment of response is more difficult in denser breasts, with ill-defined tumors, or in areas of architectural distortion alone.[25] Sonography may be more accurate with well-defined tumors but may still produce erroneous results. If conventional imaging evaluation is done during the course of chemotherapy, then this underestimation of response may cause continuation of ineffective therapy and delay in definitive treatment.
MRI provides not only an anatomic evaluation of the tumor but also a physiologic one. Necrosis and edema do not influence the MRI findings. As the MRI findings are based on the vascularity of the tumor, the effect of chemotherapy agents that inhibit tumor angiogenesis can be seen (Figure 3). In one study, specificity for partial response to chemotherapy was 93%, with 82% accuracy.[26] In addition, studies have found that MRI is better at determining the lack of response to neoadjuvant chemotherapy than at determining the extent of response.[22,26]
Rieber et al found that 56% of patients with a partial response to chemotherapy had an average MRI tumor measurement of 1.1 cm over the tumor size on final pathology. Among patients with complete response on MRI, 67% had residual tumor up to 5 cm in diameter at excision. This underestimation was more marked in invasive lobular carcinoma, with seven of nine patients showing larger tumors at final pathology than expected by MRI.[26] This discrepancy may cause difficulty for the surgeon when selecting between mastectomy and lumpectomy. The result may be positive surgical margins with increased recurrence.
The change in appearance on postchemotherapy MRI may be due to decreased tumor size, change in tumor cellularity, or change in tumor vascularity. Diminished contrast enhancement following chemotherapy would support a reduction in tumor vascularity. Decrease in peak contrast uptake and flattening of the contrast uptake curve have been seen in tumors following chemotherapy.[22,26] The shape of the contrast uptake curve is a factor in the evaluation of an enhancing lesion to determine if it is suspicious for malignancy. Due to the neovascularity, there is a greater vascular supply to the carcinoma, resulting in contrast reaching the tumor faster than the surrounding normal parenchyma. This rapid "wash in" is accompanied by a rapid "wash out" in highly suspicious lesions as the contrast moves out of the tumor through arterial venous shunting. Therefore, a tumor would be expected to have an early, steep rise to peak enhancement with a decrease in enhancement almost as quickly. The change in the contrast uptake curve may account for the underestimation of response to chemotherapy and may mask satellite lesions. If neoadjuvant chemotherapy is being considered, a prechemotherapy MRI would permit identification of the extent of the disease and allow for more accurate posttreatment evaluation.
MRI prior to initiating neoadjuvant chemotherapy is especially important if the disease is multicentric or diffuse. These lesions are not very conspicuous and become even less so with decreased contrast enhancement resulting from neoadjuvant chemotherapy. MRI can also suggest that the carcinoma is more extensive than what is found at final pathology. Rosen et al found that contrast-enhanced MRI overestimated tumor size by 1 cm or more in 33% of their patients. Most of these were nonfocal lesions.[ 22] Enhancement in diffuse disease may mimic benign breast enhancement, causing it to appear larger. MRI evaluation during the chemotherapy course may readily demonstrate a lack of response and allow earlier changes to the treatment regimen. Rieber et al found that more reliable results were obtained with contrast-enhanced breast MRI imaging performed at least 6 weeks after the initiation of chemotherapy.[26]


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OWC to Bring Aftermarket SF3700 PCIe SSD Upgrades to 2013 Macsby Anand Lal Shimpi on 1/10/2014 7:43 PM EST
24 Comments
Back to Article
MScrip - Friday, January 10, 2014 - link"All Haswell Macs..."
Finally an upgrade for the 2013 Macbook Air! Reply
SirKnobsworth - Saturday, January 11, 2014 - linkWhich of the new macs actually support x4 SSDs? The only one I know ships with one is the Mac Pro. Reply
migs647 - Wednesday, January 15, 2014 - linkThe new MacBook pros do as well. Mine came with 512, but 1tb would be nice. Reply
tKizzy - Saturday, November 28, 2015 - linkThe new 13" Macbook Air does as well. Reply
Pneumothorax - Saturday, January 11, 2014 - linkSandforce, no thanks! Too bad greedy Apple won't let their OEM's like Samsung sell these PCIe SSD's in the aftermarket. Reply
jameskatt - Saturday, January 11, 2014 - linkApple isn't stopping OEMs like Samsung from selling PCIe SSDS in the aftermarket at all. After all, Samsung sells SATA SSDs to Mac users. And Samsung already SELLS PCIe SSDs.
The problem is that Apple's Mac Pro uses FOUR PCIe 2.0 lanes, not TWO lanes as on existing PCIe SSDs. This gives the Mac Pro a maximum of 2GB/s bandwidth, twice what existing PCIe SSDs have. Since Apple is the only one doing this, and since the Mac Pro is a low volume seller, Samsung is simply not interested in creating a low volume product. If other PC Makers also would use FOUR PCIE 2.0 lanes for their SSDS, then Samsung may be interested. Otherwise, not.
OWC is great in supporting Apple's customers. And they are able to do low volume custom products. Reply
SirKnobsworth - Saturday, January 11, 2014 - linkx4 SSDs aren't unheard of. Most of OCZ's PCIe lineup seems to be x4. Kingston demoed an x4 board at CES. The M.2 products we've seen so far seem to be of both varieties, but M.2 isn't even fully adopted yet. The SF3700 (what these upgrades are going to be using) allows four lanes. Reply
Kristian Vättö - Saturday, January 11, 2014 - linkSamsung's XP941 based PCIe SSD used by Apple and several other PC OEMs (such as Sony) is x4 but many have chosen to run it at x2. Reply
jameskatt - Saturday, January 11, 2014 - linkWhat I would love is a DUAL DRIVE PCIe SSD for the new Mac Pro that you can arrange as a RAID-0. The reason is that despite the speed of the existing single-drive 4-lane PCIe SSDs from Apple, it wastes the even faster 2GBs bandwidth of the Mac Pro's SSD slot. Reply
jerrylzy - Saturday, January 11, 2014 - linkI am interested in the new SF controller performance. Reply
swat671 - Saturday, January 11, 2014 - linkThis might be a stupid question, but is it even possible to use multiple SSD's in the new Mac Pro and set them up in a RAID set up? Or would you have to use an external solution via Thunderbolt/USB? Reply
Ryan Smith - Saturday, January 11, 2014 - linkThere's only one SSD interface on the Mac Pro. A second SSD (or any other kind of storage) has to be external. Reply
SirKnobsworth - Saturday, January 11, 2014 - linkMore importantly, there aren't any more PCIe lanes left over for a second SSD, even if there's physically room for one. It would need another PLX chip. Reply
jameskatt - Sunday, January 12, 2014 - linkA RAID-0 SSD needs the chips to all be on the same card - or be in a daughter card like OWC's Accelsior PCIe SSD card. Reply
dreamer77dd - Saturday, January 11, 2014 - linkApple problably made an agreement to be the only one aloud to sell the product so they can be first. Also Apple could ohf just said will buy every pci sdd in this form factor that you produce so no one else can have it. They get it for cheap, even if premium price till makes Apple look good. Reply
jameskatt - Sunday, January 12, 2014 - linkNah. You're so funny. It is April Fool's yet? Reply
lesbedouins - Monday, January 13, 2014 - linkare every size (128, 256, 512 & 1024 Go) 4x aware ? Reply
Hrel - Monday, January 13, 2014 - linkOWN Trivia factoid: They're based out of this little shit town in Illinois called Woodstock. There's really no reason anyone should ever go there unless you own a farm. The building is almost entirely powered by a wind mill they set up on their property. Reply
Hrel - Monday, January 13, 2014 - linkOWC*
Fucking hell I hate anandtech's comment section. Editing needs to be enabled and email alerts, AT LEAST ALERTS, need to be enabled. Reply
pullman - Monday, January 20, 2014 - linkGreat news.
Btw, when will you review the 13" retina MBP? Reply
TheeGooch - Thursday, February 20, 2014 - linkI kind of need it now, lol. I went with 256GB because I didn't plan on dual booting Windows apps/games when I bought my Macbook Air 3 months ago. Now that I am, I need a lot more storage space.
Note to self, next time you buy a Macbook, max out storage. Reply
Gehard - Sunday, March 02, 2014 - linkI am now VERY skeptical of the OWC SSD's. I got an MBA w/ 126 GB SSD in 2010. I replaced the drive w/ OWC's 240GB one. Since then two SSD's went bad and I am now on the third one. Is this usual or acceptable? I would like to know... On top of that, the OWC has a policy that requires you to send the bad unit to them first before getting a warranty replacement! What kind of logic is that? So, am I supposed to stop what I am doing, get the drive out, send it to them, wait until they verify that the drive is indeed bad, and wait more until they ship the replacement? Do they think I use a Mac for a hobby? I want to know the others' experience with the OWC drives' reliability. What's AnadTech's opinion on this? Reply
phillyry - Thursday, August 07, 2014 - linkGood question. I've been considering buying and the upgrading a rMBP with an OWC drive to get the extra external but this and the power use are both pretty key. I'd check OWC forums or elsewhere for the reliability of their drives. I know that with a first gen SF Corsair drive, I had to send it back before they sent me a new one. Rediculous. Reply
Maryinuz - Friday, August 22, 2014 - link@Gehard: Try the 'new' Transcend Jetdrive upgrade kits, I was about to order one until I finally realised that my Macbook is a 2013 one and not compatible.
I did go through the whole thread on macrumors.com, Transcend offers a good package at fair price. Reply


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Executive Committee Meeting Notes
Friday, January 9, 2009
8:30 a.m., Ka Lama 102
In attendance: Pat Adams, Herman Anaya, Michele Katsutani, Katie McMillan, Diane Meyer, Karen Muraoka, Suzette Robinson,
Clyde Sakamoto, Alvin Tagomori, David Tamanaha, Marilyn Umetsu
Agenda Item
Discussion Notes
Action Items
Reports from Vice-Chancellors and Administrators
Administrative Affairs – David
▪ Update on Management Services Contract
Committee evaluated two proposals and are now awaiting submission of evaluation sheets. In the meantime, Chris is making reference checks. Committee plans to make a preliminary selection of a company and have the company make a presentation.
▪ Update on Re-organization
A draft has been distributed to faculty and staff; deadline for comments is Jan. 21.
Final draft to be sent to system on Friday, Jan. 23.
Assistant Dean position to be described to support both academic support and instruction.
▪ Update on Sculpture
Right of Entry will be executed shortly; construction should commence in a few weeks.
▪ Anticipated System-wide Budget Shortfall Update
No change
UH presentation to legislature next Tuesday. Council of Revenues will also be reporting. If Council reports less revenues, may affect how legislature will appropriate. Next Thursday, House Finance and Senate Ways and Means.
Next Friday, Higher Education Committee – John Morton to present.
▪ Budget Restrictions Update
No change
▪ Revenue Update
As of January 4, 2009, $1,939,683 (target amount is $2,011,242)
Completing the design for new Science Building; will be going out to bid in August.
▪ Energy RFP
6 companies were pre-approved by the State. After a preliminary review of the 6 companies, the committee will select 3. RFP will then be sent to the 3 companies.
CS to call Abe to find out status.
Student Affairs – Alvin
▪ Spring Enrollment Update: 2,981 students; 449 up from last year at this time. Highest enrollment last year: 2,861; 2,016 students enrolled in fall 2008 and now enrolled in spring 2009. 1,198 students enrolled in fall but not in spring (as of Friday, January 9, 2009).
▪ Update on unpaid tuitions
Alvin going through list (130 students with unpaid balances from Fall '08) to see what was unpaid and whether students have received grades. Students called have expressed willingness to pay.
Typically In the UH System, if students do not pay, they're unable to register anywhere in the system; now, however, Manoa is allowing students to register if they agree to a payment plan.
71 students
Debit balance - $73,000
▪ Online Applications – Alvin to provide update: Program still not usable.
Kamaaina application is working well; counselor from Maui High School dropped off 100 applications.
▪ Kulanaa`o – Rental policy
150 students in student housing. A building is full; C is halfway full. B building being used for short-term housing.
An email was sent to Agora expressing concern that student housing is being used for the general public.
Hale Haumana: need to decide which offices will move into the building and when. Second floor occupancy OK if space is available on first floor for meetings.
Academic Affairs – Suzette Robinson
▪ Update on ATP
Gerontology: Nancy and Lee are revising the ATP to include more social services.
Information Technology: Currently under review by the STEM dept.
Sustainable Sciences: Currently under review by the STEM dept. with a sub-committee leading. Positions under continuous recruitment; four applicants. Advertised at UH, Treehugger, Chronicle.
Applied Engineering: Program proposal will be out this week.
Applied Ocean Sciences: Approved by STEM and being reviewed by the curriculum committee.
RDP has supported curriculum development for various programs over the years.
▪ China Trip follow-up
Suzette to organize get-together with Maui Chinese community groups.
Met with HOST, Culinary; sent HOST curriculum to Shanghai University; looking at 2+2 program.
▪ Technical Committee and Donation of computers – update from Diane:
Donor gave $150,000 to art program; wants to furnish laptops to students in need. Meeting January 14, 2009; to consider making the fund sustainable.
▪ Elaine reported on separation of Early Childhood and Human Services numbers; working with Stephen Kameda. Lee will be taking the lead; change should occur by next fall. Of 168 Human Services majors, 56 are Early Childhood (does not include Moloka`i). College has two Early Childhood faculty, one Human Services.
▪ Dental Hygiene Degree update – change in progress.
ACCJC determined that a sub-change is necessary; to consider application at February 2009 meeting.
▪ Program Reviews (healthy, unhealthy, cautionary) –new system matrix designates program efficiency, effectiveness, and demand. Overall, 5 Maui CC programs healthy; 1 program unhealthy; 12 cautionary.
Results of the matrix are being questioned, e.g., nursing program judged "cautionary" because the program is not meeting the demand for nurses in the community.
Some colleges are not posting the results of the program reviews.
Suzette to check with Cheryl Chappell-Long.
Chancellor's Report
Chancellors Advisory Council
County Projects
Provided information on County request:
$500,000 – Allied Health
$270,000 – Aging with Aloha
$100,000 – Renewable Energy Proposal. ( OED asked if we could reduce by $50,000.)
▪ Legislative Activities
Board approved 3 items for Maui CC:
$3.157 million for furniture & equipment for new science building
Asbestos removal
Long range development for Moloka`i (not in executive budget).
Strategic Plan Outcomes Update
Approval of ATPs – MCC addressing community and business needs (asking for feedback from Business Advisory Council).
Suzette to present outcomes at the faculty meeting; past years' accomplishments to be edited to reflect all that occurred.


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Sept. 27, 2012
LARAMIE, Wyo. -
National Scholar-Athlete Candidate class
The semifinalists for the 2012 National Football Foundation's National Scholar-Athlete Awards, presented by Fidelity Investments, and the William V. Campbell Trophy, endowed by HealthSouth, were announced on Thursday. University of Wyoming senior free safety Luke Ruff was one of the 147 student-athletes in the nation at all levels of college football to be named to the list. Ruff was one of only 50 NCAA Football Bowl Subdivision (FBS) student-athletes and the only student-athlete from a Mountain West Conference school honored this year.
The Campbell Trophy, which has also been referred to as the "Academic Heisman", is presented annually to the top football scholar-athlete in the nation.
On Oct. 25, 2012, the NFF Award Committee will select up to 16 recipients of the NFF National Scholar-Athlete Awards. Those recipients will each receive an $18,000 postgraduate scholarship, and will become finalists for the 2012 Campbell Trophy. Each of the finalists will travel to New York City for the 55th Annual NFF Awards Dinner on Dec. 4, 2012, at the Waldorf-Astoria where this year's winner of the Campbell Trophy will be announced. The winner receives a 25-pound bronze trophy and an additional $7,000 in postgraduate money, bringing their total to $25,000.
"We are extremely proud of Luke (Ruff) being recognized among the top student-athletes in the nation," said UW head football coach Dave Christensen. "He is a great team leader for our program on and off the field, and to accomplish what he has as an engineering major on top of his accomplishments as a football player shows how truly special of a young man he is."
"Luke Ruff represents the best in college athletics," said UW Athletics Director Tom Burman. "He has represented our athletic department and our university in as fine a manner as you can ask of a student-athlete. Luke is proof that with hard work and dedication you can achieve your goals both as a student and as an athlete."
To qualify for the NFF's National Scholar-Athlete Awards, a student-athlete must: be a senior or graduate student in their final year of eligibility; have a cumulative-grade-point average of 3.20 or better on a 4.00 scale; have outstanding football ability as a first team player or significant contributor; and have demonstrated strong leadership and citizenship.
Ruff, a native of Castle Rock, Colo., carries a 3.59 cumulative-grade-point average in civil engineering, and is one of four team captains for the Cowboys this season. He earned Second Team All-Mountain West Conference honors from conference head coaches and media members as a junior in 2011. He was voted by conference media members as a 2012 Preseason First Team All-Mountain West selection at this summer's Mountain West Media Days. As both a sophomore and junior, Ruff was selected to the CoSIDA Capital One First Team Academic All-District VII team, and he has earned Mountain West Scholar-Athlete and Academic All-Conference honors each of the past three years.
The University of Wyoming has had four former student-athletes advance on as finalists for the William V. Campbell Trophy and earn postgraduate scholarships from the NFF. Those four were: guard Pat Smyth in 1959; linebacker Marty Eliopulos in 1986; center Trenton Franz in 2004; and strong safety John Wendling in 2006.
2012 NFF National Scholar-Athlete Candidate Notes
3.57 Average GPA
29 nominees with a 3.80 GPA or better
91 Team Captains
74 All-Conference Picks
21 Academic All-America Selections
14 All-America Selections
50 Nominees from the Football Bowl Subdivision
35 Nominees from the Football Championship Subdivision
12 Nominees from the Division II
41 Nominees from the Division III
9 Nominees from the NAIA
68 Offensive Players
53 Defensive Players
26 Special Teams Players


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The announcement that a plutonium-powered robot named Curiosity has landed on Mars has created great excitement among space-o-philes and NASA-nicks and the rest of the science world. However, along with the frisson of expectation, I also feel a slight sinking of the stomach. See, the ready-to-wear show schedule is such that while the rest of the world is preparing to go on vacation propelled by the news, the fashion world is preparing to sit down at their desks to start creating their spring/summer collections. With space travel at the front of their minds.
Read more
© The Financial Times Ltd 2016 FT and 'Financial Times' are trademarks of The Financial Times Ltd.


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I've tried heavy duty trigger spray bottles, pump up kitchen spray bottles (which work but kinda peter out quickly (no comments)). and the medium size top pump things that the
"EVIL ORANGE EMPIRE" sells (sorry Vinsect, I own stock too , it's just funnier that way).
Most can't pass the oil at all or won' t mist it and just splat out this weak little stream.
Any luck?
I used to keep large covered coffee can filled with and inch or so of oil. A 3" natural bristle paintbrush with the handle cut off so it would close. I would use this to lube the grates. But it picked up bits and pieces of undesirables and got funky pretty quickly.
Ideas. (NOT PAM)


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Hey there, time traveller!
This article was published 13/9/2013 (1438 days ago), so information in it may no longer be current.
The evaluation rosters have been assembled for the Manitoba Under-18 women's and Under-16 men's hockey teams.
The Under-18 evaluation team is playing a three-game exhibition series against the University of Manitoba Bisons women's team at Max Bell Centre this weekend, with games Friday and Saturday evening at 7 p.m. and Sunday afternoon at 2 p.m..
The final Under-18 women's team will go on to represent Manitoba at the National Women's U-18 Championships, Nov. 6-10 in Calgary.
The Under-16 men's evaluation team will play an exhibition game Sept. 29 against the Winnipeg Thrashers at MTS Iceplex. Game time is 6:20 p.m..
The final Under-16 men's team will represent Manitoba at the Western Canada U-16 Challenge Cup in Calgary, Oct. 31-Nov. 3.