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Nivea Eye Make-up Remover Reviews
Come back!This was, yes, I said "was", my favorite drugstore eye makeup remover. I believe this was unfortunately discontinued here in the US. I have not seen the whole Nivea Visage line for some time. This remover was a creamy lotion, not a liquid-based remover. It was gentle enough for my eyes, but strong enough to take off most of my eye makeup. It never irritated my eyes. It may have not been the best one, but it was the best in the price range. — 6 years, 9 months agoluckybetty | 895 reviews
This review is: Helpful | Not helpful | Inappropriate | 1 of 1 people said helpful
NiceNice, clean and simple quality with a great price makeup remover, I like it! — 8 years, 3 months agobrassa | 447 reviews
This review is: Helpful | Not helpful | Inappropriate | 0 of 1 people said helpful
Outstanding ProductI wish more people would try this eye makeup remover! I hope they never stop making this stuff. Even great with Definicals mascara! Always use remover and not soap which is too drying for the eye area. Sometimes hard to find so I buy several at a time and keep in the refridge to keep fresh. — 8 years, 5 months agoYdabney | 15 reviews
This review is: Helpful | Not helpful | Inappropriate | 1 of 1 people said helpful
Okay but not great...Gave this one a try because it was more affordable then the Mary Kay eye make up remover. I wasn't really too impressed with this product. Lesson learned on this one "You pay for what you get". — 7 years, 3 months agoLauraESPN | 7 reviews
THE BEST MAKE-UP REMOVER EVER - STOCK UP NOW WHILE SUPPLIES LAST!!!!!!I've searched and searched - and you can stop here. This is the best remover there is for eyes and face. Gentle. No water needed. Just apply and tissue off. great for getting off waterproof mascara. — 7 years, 9 months agoswalterdc | 1 reviews
This review is: Helpful | Not helpful | Inappropriate | 3 of 5 people said helpful
Finally!!!Finally a makeup remover just for the eyes. Because let's face it eye makeup is harder to remove than regular face makeup (foundation, concealer etc.) especially mascara and liner. This works great it's gentle but, to be honest I bought it once I saw Nivea. I love all Nivea products they always leave your skin so soft and gentle. — 5 months, 3 weeks agoMakeupmela | 48 reviews
This review is: Helpful | Not helpful | Inappropriate | 4 of 4 people said helpful
not sure why it doesn't work for me...i guess it removes my eye shadow and liner ok, but so does just using face wash. i need eye make up remover specifically for my waterproof mascaras, and this stuff removed VERY little (if any at all). not sure how long i have to leave it on to sink in, but i had it on for at least 15 seconds and it didn't dissolve the mascara. plus, sitting around with my eyes closed with gook all over it for that long is annoying. will stick to the MUCH better clinique eye make up remover. — 8 years, 3 months agokhat12 | 42 reviews
Works great for removing makeup!It's gentle for my sensitive, overly worked up skin. It's not greasy at all and it doesn't leave any weird residue which makes me want to wash it off. In fact, it does leave the area a bit soft like there is a bit of moisturizer in it which is an even better benefit, I don't have to immediately slap on more lotion after using the product. It removes makeup well and even waterproof makeup comes off...read more with this product, although you have to work at it a little bit more with a tissue. I usually don't use makeup remover, I usually just wash it off in the shower, but when I do, this is a great product to use. It's also not very expensive which is another plus. — 8 years, 4 months agopiccalily | 26 reviews
Great but hard to find.This is one of the best eye makeup removers I've used. I was very pleased when I bought it in place of my (much)more expensive remover. But, when I was out, I could not find it in the stores to purchase again. Any suggestions? — 8 years, 4 months agojbennns | 1 reviews
This review is: Helpful | Not helpful | Inappropriate | 0 of 1 people said helpful
So GentleI love this makeup remover, it has to be one of my favourites. It's so gentle and doesn't sting my eyes like a lot of others tend to do. It removes makeup quite thoroughly although it does leave just a tiny bit behind. — 8 years, 4 months agoLollirot | 4 reviews
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My Reasons for Reporting This


text:
While I'm standing in the torrential rain covering a football game, I hope you are all happy and dry watching the hockey game.
Here, cut and pasted from Tom Gulitti's Fire and Ice blog (he rules, by the way, and he also has some details on this afternoon's rookie game, won by the Rangers, 5-4), is the Devils lineup:
Forwards: Ilya Kovalchuk-Jacob Josefson-Nick Palmieri, Mattias Tedenby-Adam Henrique-Petr Sykora; Rod Pelley-David Steckel-Vladimir Zharkov; Eric Boulton-Tim Sestito-Brad Mills.
Defensemen: Anton Volchenkov-Andy Greene; Bryce Salvador-Adam Larsson; Matt Taormina-Mark Fayne
Goaltenders: Martin Brodeur, Keith Kinkaid.
I'm assuming that Wolski is going to start on the left of Richards and Gaborik, but that a number of guys are going to get a look there, including Brian Boyle and Mike Rupp, and maybe even Ruslan Fedotenko and Derek Stepan. If not tonight, then soon.
Here is the Rangers' lineup:
Forwards: Brian Boyle, Ryan Callahan, Ruslan Fedotenko, Marian Gaborik, Carl Hagelin, Kris Newbury, Brad Richards, Mike Rupp, Derek Stepan, Dale Weise, Wojtek Wolski, Mats Zuccarello.
Defensemen: Brendan Bell, Michael Del Zotto, Tim Erixon, Ryan McDonagh, Michael Sauer, Pavel Valentenko.
Goaltenders: Martin Biron, Chad Johnson.

subset: commoncrawl


text:
Damion Reid
With MEINL since:
June 16, 2010
Zodiac Sign:
Place of birth:
West Covina, CA
Currently living in:
Brooklyn, NY
Drumming since:
Age three.
Car that you currently drive:
I am driven, but I don't drive.
Not counting on drums what do you do for fun:
Favorite Food:
Favorite Drink:
Billy Higgins and various musicians.
Highlight of your career so far:
Having a snare drum inspired and named after myself, by master craftsman Adrian Kirchler.
Drumming strengths:
Knowing that I have a lot to learn.
Drumming means to me:
The ability to communicate personal ideas with complete control, while adapting to the music without fluctuating the intended groove.
Advice for up and coming drummers:
Always be open to listening and studying anything because, you can learn something from anybody.
How would you describe yourself:
Brown complexion, 5' 10", brown eyes, black hair and an athletic build.
When I look back on my life one day, I would like to be able to say:
I did it my way.


text:
You deserve to get paid for your work. End of story.
Unfortunately, getting paid may not always be such an easy feat.
Here are a number of tips to help ensure that you get paid for the
work that you do:
Select Your Clients with Care.
Use Your Fee Agreements.
Collect Money Up Front.
Bill Early and Often.
Keep in Touch with Your Clients.
Don't be Afraid to Get Out.
Collections as a Last Resort.
Tip courtesy of Heidi Alexander, Law Office Management Assistance
Published March 21, 2013


text:
7th Fl. (Century City)
Los Angeles, California 90067
United States
|Areas of Practice
|1) Corporate
|Admitted Year
|Cornell University (B.S., Applied Economics and Bu
|Most recent firm
|O'Melveny & Myers LLP
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A. Harrison Barnes is a well-known attorney throughout the United States. As a member of the Malibu community, Harrison is committed to serving the needs of Malibu residents and businesses in legal matters.
Alan Singer is a partner in Morgan Lewis's Securities Practice. Mr. Singer advises companies with regard to a diverse range of corporate and securities matters.


text:
Security Council: Statement by Ambassador Wittig on Syria
Merci Monsieur le Président,
many thanks to Deputy Secretary-General Eliasson and High Commissioner Guterres for their briefings.
I wish to thank the French Presidency for its initiative to call for today's meeting. It comes at a very important moment.
The Syrian people require our urgent support. We have heard again today that the humanitarian situation is dramatic and worsening by the day.
We are grateful and we commend the governments and the people of Jordan, Lebanon, Turkey and Iraq for their crucial support provided to Syrian families fleeing from the brutal violence of the Assad regime and its militias.
My government, as part of the international efforts, provides substantial financial support for relief efforts undertaken by UN agencies and the International Committee of the Red Cross both within Syria and in neighboring states and I assure you it will continue to do so.
An improvement of the humanitarian access inside Syria is essential in order to help the people in need. We therefore call upon all parties to facilitate humanitarian access in all parts of Syria .
Mr. President,
The humanitarian situation will not improve unless the Syrian people can live free from fear. The continuing attacks against civilians and the massive human rights violations by the Assad regime must stop.
The use of heavy weapons, helicopter gunships and fighter planes show the extreme brutality that Damascus employs against the Syrian people.
Today's meeting also comes only a few days following reports of yet another massacre committed by the regime and its militias against civilians, including women and children.
Accountability for such crimes must be ensured. The Independent Commission of Inquiry has provided important findings, and it has compiled a list of those deemed responsible. This provides a solid base for possible follow-up action, including the International Criminal Court.
We also call on the opposition to respect international humanitarian law and to protect civilians. More leadership and dedication is required. The publication of a Code of Conduct of the Free Syrian Army is a first step in the right direction. Humanitarian law applies to all sides.
Mr. President,
My government will continue to work towards a political solution of the crisis. This includes a political transition toward a democratic and tolerant Syria - a Syria that embraces all Syrians and ensures their human rights, irrespective of their origin or religion.
The United Nations continue to play a central role in supporting the Syrian people in finding a political settlement and in embarking on a democratic transition. The same is true for the Arab League, which has from the start played an active and constructive role.
I want to assure Joint Special Representative Lakhdar Brahimi of Germany 's full support for his challenging new task.
We are also engaging closely with the opposition – both bilaterally and within the Friends of Syria Group - to prepare the ground for the post-Assad Syria. It is in the interest of all of us to avoid a total breakdown of Syria , which would also pose a serious threat to regional stability.
Mr. President,
Our position is clear: There can be no future for President Assad in a new Syria. We call on President Assad to step aside to avoid further bloodshed.
The chemical weapons stocks in Syria pose a serious threat. The use of chemical weapons would be a disastrous escalation of the situation with unpredictable consequences for Syria and the entire region. We urge Syria to abide strictly by its obligation, under international law, not to use chemical weapons under any circumstances. We also call upon Syria to guarantee the secure and safe storage of these weapons of mass destruction.
I thank you, Mr. President.


text:
DETECTIVES are investigating the deaths of two men whose bodies were found at a house in Bebington in the early hours of this morning.
Police entered a house on Kennet Road at just after midnight following reports of concern for the safety of a man.
Once inside, they found the bodies of two men aged 47 years and 54 years. At this time, their deaths are being treated as unexplained.
It is not known how long the bodies had lain undiscovered.
Officers from the police search and rescue unit arrived at the house as part of the investigation.
Next of kin are now in the process of being informed.
Formal identification is still to take place.
Post-mortem examinations will be carried out in due course and a full investigation into the circumstances surrounding the incident is continuing.
It is believed one of the men was the other's carer.
Neighbours in the quiet cul-de-sac expressed their shock following the grim discovery.
One, who had lived in the area for 14 years, told the Globe: "This is the first time anything like this has happened. It's a terrible shock."
Another, who also wanted to remain anonymous, said: "There were 'wall-to-wall' police in the road after the bodies were found. We had no idea what was going on at the time."
Anyone with information is asked to call Merseyside Police on the 101 non-emergency number.


text:
En attente de modération
I'd love to know the lyrics to the song 'Mdlwembe' by Zola, the South African kwaito artist. I think the lyrics are in Zulu, but I'm not sure. I can't find them anywhere! It's really frustrating, because it's such a good song!
Can anyone help me?


text:
Note: This item is more than 10 years old. Please take the publication date into consideration for any date references.
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News Release
Media Contact: TPWD News, firstname.lastname@example.com, 512-389-8030
Nov. 2, 2006
New Agreement To Help Texas Landowners Conserve Lesser Prairie Chicken
Joint News Release: U.S. Fish and Wildlife Service and Texas Parks and Wildlife Department
AUSTIN, Texas — A new agreement between the Texas Parks and Wildlife Department (TPWD) and the U.S. Fish and Wildlife Service (USFWS) is expected to help private landowners conserve the lesser prairie chicken, a rare bird whose fate is tied to the health of grassland ecosystems that sustain many other wildlife species.
A signing ceremony for the agreement will take place at the beginning of the Texas Parks and Wildlife Department Commission meeting on the morning of Thursday, November 2 at TPWD headquarters in Austin.
By undertaking voluntary conservation measures on their property under the new agreement, landowners will be assured that no further land use restrictions or conditions will be required from them if the lesser prairie chicken is ultimately listed under the federal Endangered Species Act. The bird is currently a candidate for listing.
"The proposed Candidate Conservation Agreement with Assurances (CCAA) encourages beneficial habitat management activities among private landowners on a voluntary basis," said the USFWS Southwest Regional Director Benjamin N. Tuggle, Ph.D. "The Service believes there is a need for a CCAA to increase economic incentives and remove legal disincentives for landowners to allow candidate and/or listed species on their property. These types of incentive based programs go a long way to contributing to species conservation and recovery."
Under the new agreement, TPWD can issue a one-page Certificate of Inclusion signed by a landowner who wishes to voluntarily commit to undertake certain conservation actions outlined in their TPWD-approved wildlife management plan. Such landowner actions would include measures such as brush control, grazing management, prescribed burning, and allowing periodic monitoring on their property.
Approximately 15 Texas landowners already have working relationships with TPWD for grassland conservation that benefits lesser prairie chickens. In addition, the USFWS has used its Partners for Fish and Wildlife Program to restore or enhance lesser prairie chicken habitat on approximately 82,631 acres in the Texas Panhandle. These projects have involved 43 different landowners in 11 counties, all of which could qualify for inclusion under the CCAA.
"We have Texas landowners who already qualify to sign up under this new agreement, ranchers who are voluntarily conserving and managing grasslands in ways that benefit prairie chickens and other species," said Mike Berger, TPWD wildlife division director. "Over time, we think this will be an important additional tool for Texas private landowners, many of whom have demonstrated the desire and ability to do the right thing for wildlife and habitat."
Since more than 95 percent of the Texas landscape is privately owned, the voluntary cooperation of ranchers and other rural landowners is considered essential for wildlife conservation in the state.
Lesser prairie chickens were once found throughout short and mid-grass prairies in Texas, Oklahoma, Kansas, Colorado and New Mexico. Since 1963 scientists believe prairie chicken numbers have declined 80 percent nationwide due to habitat loss and fragmentation, population isolation, drought and land-use and land-cover changes. Today in Texas, lesser prairie chickens are currently found only in two isolated areas in the northeastern and southwestern corners of the Panhandle region.
In 1997, the Lesser Prairie Chicken Interstate Working Group was formed to prepare a range-wide conservation strategy to coordinate efforts among the five states with occupied prairie chicken habitat.
"Prairie chicken conservation equals grassland conservation," said Heather Whitlaw, TPWD wildlife biologist in Lubbock. "Landowners who provide good habitat for this bird are helping many other grassland-dependent species, such as pronghorn antelope and many grassland birds. Further, prairie conservation equals water conservation. Restoring and managing the native grasslands of the Texas Panhandle, including regions with Playa Lakes, can provide vital recharge sources for the Ogallala Aquifer."
John Hughes, USFWS biologist in Canadian, Texas, added that "No one agency or group can accomplish lesser prairie chicken recovery alone and it will take the combined efforts of TPWD, USFWS, the U.S. Department of Agriculture and others to restore this magnificent bird to its former range."
Biologists say what is needed to help the bird is to create and/or maintain large blocks of suitable habitat. To do this, land managers should provide low vegetation for breeding grounds, tall bunch grasses/shrubs for nesting cover, areas with overhead cover that are open underneath for birds to raise their chicks, a year round food supply and protection from weather. All these elements should be within three-to-five miles of the spring breeding areas.
In recent years, the federal Natural Resource Conservation Service has worked with other agencies, including TPWD and USFWS, to establish a Wildlife Emphasis Area within the federal EQIP cost-share program, with $135,000 set aside for the lesser prairie chicken habitat conservation in 2006. Texas has also increased lesser prairie chicken research and program funding for projects such as land cover and land use mapping, aerial survey evaluations, population-level modeling, and population surveys. The department also supports landowner initiatives such as the Texas Panhandle Prescribed Burn Association.
For more information about the new Candidate Conservation Agreement with Assurances for the lesser prairie chicken in Texas, interested landowners should contact Whitlaw at (806) 742-4968 or Hughes at (806) 323-6636.
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Fontenete, S., Leite, M., Cappoen, D., Santos, R., Ginneken, C.V., Figueiredo, C., Wengel, J., Cos, P. and Azevedo, N.F.
Notes: Researchers were interested in detecting Helicobacter pylori infecting C57BL/6 mice in vivo using a fluorescent probe specific for the 16S rRNA gene. To test if the probe, Cy3_HP_ LNA/2OMe _PS, was cytotoxic to cells, the human gastric epithelial cell line AGS was seeded in a 96-well plate at 1.6 × 105 cells/well and the next day, medium changed and 0.4–2 µM of probe or vehicle only was added to the AGS cells. After 24 hours, cell viability was determined using the CellTilter 96® Aqueous One Solution Cell Proliferation Assay. The potential genotoxicity of the H. pylori-specific probe was assessed using the VITOTOX® Assay, and the luminescent signal measured every 5 minutes over 4 hours using the GloMax® Discover System. (4749)
Expand Full Notes »
GloMax® Discover System
CellTiter 96® AQueous One Solution Cell Proliferation Assay
Kong, L.R., Chua, K.N., Sim, W.J., Ng, H.C., Bi, C., Ho, J., Nga, M.E., Pang, Y.H., Ong, W.R., Soo, R.A., Huynh, H., Chng, W.J., Thiery, J.-P. and Goh, B.C.
Notes: The effect of overexpression of MAP2K1 (D67N) was assessed in the Calu-1 human cells through transfection with ViaFect™ Transfection Reagent (details not provided). The effect of 72 hour cisplatin exposure on 13 different human lung cell lines was assessed with the CellTiter 96® AQueous One Solution Assay. All cells were authenticated through STR analysis using the GenePrint® 10 System. (4682)
ViaFect™ Transfection Reagent
GenePrint® 10 System
Expand Products »
Tokumoto, M., Kutsukake, N., Yamanishi, E., Katsuta, D., Anan, Y., and Ogra, Y.
Notes: Total RNA was isolated from untreated HepG2 cells to clone the AS3MT transcript by RT-PCR, and for RT-qPCR analysis following AS3MT-directed siRNA treatment. The total RNA was isolated with the ReliaPrep™ RNA Cell Miniprep System. The health of the siRNA-treated cells was monitored with the CellTiter 96® AQueous One Solution Cell Proliferation Assay. (4620)
ReliaPrep™ RNA Cell Miniprep System
Agrawal, V., Woo, J. H., Mauldin, J.P., Jo, C., Stone, E.M., Georgiou, G. and Frankel, A.E.
Notes: The authors used the CellTiter 96® AQueous One Solution Cell Proliferation Assay (MTS) as a third assay (in addition to 3H thymidine and 3H leucine assays) to assess the response of cells to CoArgIPEG and demonstrated not only a decline in cell survival with treatment but also a decline in proliferation and protein synthesis in most cases.
The CellTiter 96® AQueous One Solution Cell Proliferation Assay (MTS) was also used to evaluate the effect of recovery in cancer cells. The authors determined that prolonged treatment resulted in cytotoxicity; however, assessment at 24 hours showed that some cells survived in the short term. Because the authors knew proliferation/protein synthesis inhibition was occurring, evaluation with a cell survival assay like the CellTiter 96® AQueous One Solution Cell Proliferation Assay (MTS) was required for a more complete understanding of cellular health and response. (4511)
Erlendsson, L.S., Muench, M.O., Hellman, U., Hrafnkelsdóttir, S.M., Jonsson, A., Balmer, Y., Mäntylä, E. and Orvar, B.L.
Notes: The authors explore barley (Hordeum vulgare) as a means of expressing recombinant human Flt3 ligand, which is a growth factor involved in proliferation and differentiation of stem cells and development of various immune cells. As part of their quality control, they performed in-gel proteolytic digestion and mass spectrometry. The recombinant Flt3 ligand was analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis, followed by Coomassie® blue staining, excision of the protein band, destaining, drying of the gel slice and digestion with Sequencing Grade Modified Trypsin at 30°C overnight prior to mass spectrometry. To test biological activity, the authors treated human acute myeloid leukemia cells with Flt3 expressed in barley or a commercial source of Flt3 then measured cell proliferation using the CellTiter 96® AQueous One Solution Cell Proliferation Assay. (4352)
Sequencing Grade Modified Trypsin
Sequencing Grade Modified Trypsin, Frozen
Cho, Y.Y., Tang, F., Yao, K., Lu, C., Zhu, F., Zheng, D., Pugliese, A., Bode, A.M. and Dong, Z.
Notes: This paper examined the role of the Cdk3/c-Jun signaling in EGF-stimulated cell proliferation and cell transformation. An AP-1 luciferase reporter plasmid construct was contransfected with various expression vector combinations of Cdk3, Cdk2, c-Jun, c-Jun M63/73, Cdk3-DN and cyclin C and the phRL-SV40 Vector as a normalization control. Cells were lysed at room temperature for 30 minutes with gentle shaking and luciferase activity measured using the Dual-Luciferase® Reporter Assay System. SaoS-2 cells transfected with a mock and Cdk3 RNAi vector were seeded at a density of 4 x 103 in 96-well plates with 20µl of medium. After 24 hours, 20µl of CellTiter® 96 AQueous One Solution was dispensed to each well, and the plate incubated for 1 hour at 37°C. The reaction was stopped using 25µl of 10% SDS and absorbance was measured at 492 and 690nm. For the CheckMate™ Mammalian Two-Hybrid System, the plasmid constructs, pACT-c-Jun, pBIND-Cdk3 and pG5luc, were cotransfected into HEK293 cells at no more than 100ng/well in a 48-well plate. After incubation and lysis, 20µl of lysate was dispensed into each well of a 96-well luminescence plate. Firefly and Renilla luciferase activity was detected. (4028)
CheckMate™ Mammalian Two-Hybrid System
Dual-Luciferase® Reporter 1000 Assay System
Dual-Luciferase® Reporter Assay System
Dual-Luciferase® Reporter Assay System 10-Pack
Wilson, P.M., Fazzone, W., LaBonte, M.J., Lenz, H.J. and Ladner, R.D.
Notes: The authors examined the role of p53 in modulating dUTPase promoter activity. Base substitution mutations of Sp1- and E2F-binding sites in the dUTPase promoter were performed using the GeneEditor™ in vitro Site-Directed Mutagenesis System. Each mutant was confirmed by DNA sequencing. To determine growth inhibition, HCT116 human colon cancer cells were seeded in 96-well plates at 3 × 103 cells/well and treated with 5-fluorouracil (5-FU), fluorodeoxyuridine (FUdR), oxaliplatin or in combination. After 72 hours, the CellTiter® 96 AQueous One Solution was dispensed into each well and absorbance measured. RNA was isolated from HCT116 p53+/+ and HCT116 p53-/- cells. cDNA was reverse transcribed from 200ng total RNA followed by multiplex qPCR using the Plexor™ qPCR System to amplify dUTPase, thymidylate synthase and GAPDH, a housekeeping gene. The 1.2 kb region of the dUTPase promoter upstream of the transcriptional start site was amplified by PCR and the fragment cloned into the pGL3-Basic Vector. Truncated promoters were also generated by PCR and cloned into the same vector. Drosophila SL-2 cells and HCT116 cell lines were seeded in a 24-well plate and transfected with dUTPase pGL3 promoter constructs or with pCI-Neo:p53WT, pCI-Neo:p53MUT and the empty pCI-neo Mammalian Expression Vector; all transfections included the pRL-TK Vector at a ratio of 1:10. After six hours, the cells were incubated in either fresh medium or medium containing a cytotoxic agent at the appropriate concentration. Thirty hours later, the cells were lysed, quantitated by Western blotting and 20µl of lysate analyzed with the Dual-Luciferase® Reporter Assay System. Electrophoretic mobility shift analyses (EMSA) were performed using –64 to –91 of the dUTPase-nuclear isoform transcriptional start site in the Gel Shift Assay System. (4031)
Gel Shift Assay Core System
Gel Shift Assay System
pCI Mammalian Expression Vector
pRL-TK Vector
Zheng, D., Cho, Y.Y., Lau, A.T., Zhang, J., Ma, W.Y., Bode, A.M. and Dong, Z.
Notes: To examine the role of cyclin-dependent kinase (cdk)-3 expression in cancer cell lines, potential targets of cdk3 phosphorylation were examined. The CheckMate™ Mammalian Two-Hybrid System was used to test for transcription factor binding partners of cdk in HEK293 cells. Cell proliferation of T96G cells stably transfected with either cdk3 or vector was assessed using the CellTiter 96® AQueous One Solution Cell Proliferation Assay. (3983)
Case, M., Matheson, E., Minto, L., Hassan, R., Harrison, C.J., Bown, N., Bailey, S., Vormoor, J., Hall, A.G. and Irving, J.A.E.
Notes: The authors of this study investigated the relationship of somatic mutations that deregulate the RAS-RAF-MEK-ERK pathway and Acute Lymphoblastic Leukemia (ALL) and its progression to relapse in some patients. They show that such mutations are common in ALL and its recurrence. Furthermore, lymphoblasts from patients with mutations that were associated with upregulation of ERK showed increased cytotoxicity over wild-type controls when treated with U0126, suggesting that specific ERK inhibitors may eventually yield useful therapeutics. Following drug exposure, cytotoxic effects were assessed using the CellTiter 96® AQueous One Solution Cell Proliferation Assay. (3905)
MEK Inhibitor U0126
Wu, D., Ren, Z., Pae, M., Guo, W., Cui, X., Merrill, A.H. and Meydani, S.N.
Notes: The authors examined the role of ceramide and NF-κB in age-related adipose tissue inflammation in mice. Levels of inflammation-associated molecules, IL-1β, IL-6, TNF-α, COX-2 and peroxisome proliferator-activated receptor (PPAR)-γ mRNA, were quantified by quantitive PCR (qPCR). RNA was isolated from adipose tissues, and first-strand cDNA was synthesized using the Reverse Transcription System prior to qPCR. mRNA levels were also quantified in peritoneal macrophages grown in the presence of young adipocyte-conditioned medium and old adipocyte-conditioned medium. Viability of the primary adipocytes used in these experiments was confirmed using the CellTiter 96® AQueous One Solution Cell Proliferation Assay and CytoTox 96® Non-Radioactive Cytotoxicity Assay. (3777)
CytoTox 96® Non-Radioactive Cytotoxicity Assay
Reverse Transcription System
Muraoka-Cook, R.S., Caskey, L.S., Sandahl, M.A., Hunter, D.M., Husted, C., Strunk, K.E., Sartor, C.I., Rearick, W.A., McCall, W., Sgagias, M.K., Cowan, K.H., and Earp, H. S.
Notes: Heregulin is a growth factor that binds to the HER/ErbB family of receptors, which includes four HER members. HER1 and HER2 overexpression in breast cancer cells is associated with higher malignancy and poorer prognosis. However, HER4 expression is associated with longer survival and more positive prognosis. The authors of this study investigated HER4-dependent growth inhibition that is mediated by heregulin. The authors determined the absolute levels of HER4 mRNA in several human breast cancer and mouse cancer cell lines. For this determination, relative cell numbers were determined using a CellTiter® AQueous MTS assay. Apoptosis in heregulin-treated or untreated cells was also determined using the DeadEnd™ Colorimetric TUNEL System. The authors concluded that heregulin decreases growth of HER4-positive breast cancer cells, and that this growth inhibition is dependent on BRCA1. (3596)
CellTiter 96® AQueous MTS Reagent Powder
DeadEnd™ Colorimetric TUNEL System
Garcia-Pedrero, J.M, Kiskinis, E., Parker, M.G., and Belandia, B.
Notes: To examine the role that BAF57, a transcriptional modulator of the estrogen receptor (ER), may have in breast cancer, BT549 cells were transfected with a reporter vector (pGL3-Basic with two estrogen response elements and the human pS2 promoter), the control pRL-CMV Vector and combinations of the following expression vectors: mERα or hERβ, BAF57, SRC1e, SRC1a and RAC3. After 16 hours, the cells were treated with 17β-estradiol. Twenty-four hours later, the cells were harvested and the luciferase activities assayed using the Dual-Luciferase® Reporter Assay System. GST-BAF57 (full-length, N- or C-domain) fusion protein was bound to Sepharose beads and incubated with 17β-estradiol or vehicle and wildtype or one of various mERα interaction domain mutants, which have been expressed and labeled with 35S methionine using a TNT® rabbit reticulocyte lysate system. The beads were washed and analyzed for bound protein. ZR-75-1 cells were transfected with BAF57 siRNA then treated with 17β-estradiol 24 hours later. Cell proliferation was measured using the CellTiter® 96 AQueous One Solution Cell Proliferation Assay. (3599)
pGL3-Basic Vector
pRL-CMV Vector
Straszewshi-Chavez, A., Visintin, I.P., Karassina, N., Los, G., Liston, P., Halaban, R., Fadiel, A. and Mor, G.
Notes: The authors sought to determine the mechanism by which first-trimester trophoblasts resist FAS ligand-induced apoptosis but remain sensitive to TNFα-mediated apoptosis. First trimester trophoblasts express XAF1 [X-linked inhibitor of apoptosis (XIAP)-associated factor 1], which may be involved in regulating their response to proapoptotic signals. The authors created HaloTag™-XAF1 fusion constructs and transiently transfected the first trimester trophoblast cell line (3A). Cells were labeled with the HaloTag™ TMR ligand, and XAF1 was shown to localize to the cytoplasm. 3A cells transiently transfected with the fusion construct were also separated into cytoplasmic and mitochondrial fractions. The fractions were labeled with HaloTag™ TMR ligand. Expression of the fusion peaked at 48 hours after transfection in both mitochondrial and cytoplasmic fractions. TNFα-treatment of 3A cells induced translocation of endogenous XAF1 to the mitochondria. The authors used the Caspase-Glo® Assays to demonstrate activation of caspase-3 and caspase-9 in response to expression of XAF-1. They also show that caspase-3 activation and XIAP cleavage correlate with translocation of endogenous XAF1 to mitochondria. Viability of 3A and primary trophoblasts over expressing XAF1 was evaluated using the CellTiter® 96 AQueous One-Solution Assay. (3760)
Caspase-Glo® 3/7 Assay
Caspase-Glo® 9 Assay
HaloTag® TMR Ligand
Chang, A.J., Song, D.H. and Wolfe, M.M.
Notes: The researchers sought to determine whether PPARγ expression might direct the effects of gastrin in proliferation of colorectal cancer cells (CRC). They determined that cell line DLD-1 cells had both PPARγ and gastrin receptors. They demonstrated that gastrin stimulated CRC cell proliferation with a coincident decrease in PPARγ levels. These studies show that gastrins trophic properties could be due in part to transactivation of EGFR and phosphorylation of ERK1/2, leading to a decrease in PPARγ activation.
The authors used CellTiter 96® Aqueous One Solution Cell Proliferation Assay to measure cell growth of the CRC cell line DLD-1.
The DLD-1 cells were transiently transfected with a luciferase vector, and FuGENE® 6 Transfection Reagent was used at a DNA ratio of 3:1 in 24-well plates. To normalize for transfection efficiency, the cells were co-transfected with a β-Gal reporter construct. The Dual-Luciferase® Assay System was used to measure PPARgamma activity with values then normalized to Beta-Gal, measured with the β-Galactosidase Enzyme Assay System. (4280)
β-Galactosidase Enzyme Assay System with Reporter Lysis Buffer
FuGENE® 6 Transfection Reagent
Gauduchon, J., Gouilleux, F., Maillard, S., Marsaud, V., Renoir, J.M., and Sola, B.
Notes: Uses CellTiter 96 Aqueous One Solution for cell viability determination (3313)
Berglund, P., Stighall, M., Jirstrom, K., Borgquist, S., Sjolander, A., Hedenfalk, I. and Landberg, G.
Notes: To examine the influence of cyclin E overexpression on gene expression in breast cancer, the breast cancer cell line MDA-MB-468 was stably transfected with a cyclin E-GFP fusion construct or GFP alone. RNA from two of these clones was isolated and pooled prior to reverse transcription and labeling. The microarrays were filtered and used in GoMiner analysis. Attachment assays were also performed with the stable cell lines. In these assays, the cells were allowed to adhere to 96-well plates for 1 hour, washed with PBS and then incubated with the CellTiter 96® AQueous One Solution Cell Proliferation Assay for 1.5 hours. Absorbance was used to measure the number of attached cells. (3388)
O'Hare, T., Walters, D.K., Stoffregen, E.P., Jia, T., Manley, P.W., Mestan, J., Cowan-Jacob, S.W., Lee, F.Y., Heinrich, M.C., Deininger, M.W.N. and Druker, B.J.
Notes: Ba/F3 cells were transfected with constructs encoding either wildtype or mutant (Imatinib-resistant) Bcr-Abl kinase. Src-family kinase activity was assayed using the SignaTECT® Protein Tyrosine Kinase Peptide 2 and SAM2® Biotin Capture Membranes. Cell viability was measured using the CellTiter 96® AQueous One Solution Cell Proliferation Assay. (3405)
SAM2® Biotin Capture Membrane
SignaTECT® Protein Tyrosine Kinase (PTK) Assay System
Daly, C., Wong, V., Burova, E., Wei, Y., Zabski, S., Griffiths, J., Lai, K.M., Lin, H.C., Ioffe, E., Yancopoulos, G.D., Rudge, J.S.
Notes: HUVECs were infected with adenoviruses encoding either GFP, forkhead transcription factor (FKHR), or FKHR-TM for 24, 32, or 45 hours. At each time point, the relative number of living cells was determined by the CellTiter 96® AQueous One Solution Cell Proliferation Assay. (3155)
Ward, M., Lin, C., Victoria, D.C., Fox, B.P., Fox, J.A., Wong, D.L., Meerman, H.J., Pucci, J.P., Fong, R.B., Heng, M.H., Tsurushita, N., Gieswein, C., Park, M., Wang, H.
Notes: Aliquots of 1.8 x 103 cells were placed in 96-well microtiter plates and the cells were allowed to adhere for 6 hours before medium containing two-fold serial dilutions of Aspergillus niger-derived antibody from 20 to 0.078 g/ml (final concentrations of 10 to 0.039 g/ml) or medium alone then were added to the wells. After 72 hours incubation, relative proliferation was measured by using the CellTiter 96® AQueous One Solution Cell Proliferation Assay (3153)
Mayo, J.J., Kohlhepp, P., Zhang, D., Winzerling, J.J.
Notes: A549 cells were grown to 80% confluence before being exposed to smoke or sham air for 4, 6 or 22 hours. Cells were harvested by trypsinization and viability was determined using the CellTiter 96® AQueous One Solution Cell Proliferation Assay. (3165)
Thottassery, J.V., Sun, Y., Westbrook, L., Rentz, S.S., Manuvakhova, M., Qu, Z., Samuel, S., Upshaw, R., Cunningham, A., Kern, F.G.
Notes: Subconfluent ML20 cells were stripped of estrogens over three days then plated in a 96-well plate at 5000 cells/well. After overnight attachment, the cells were treated with fresh media containing 5% FBS plus ICI 182780 with or without each of the following: heregulin, epidermal growth factor; fibroblast growth factor 1 and β-estradiol or each of the factors individually. Under these various media conditions, the cells were treated with U0126. After five days, the cells were assayed using the CellTiter 96® AQueous One Solution Cell Proliferation Assay. (3154)
Chaea, S.Y., Leeb, M., Kimb, S.W. and Baeb, Y.H.
Notes: The authors studied the effect of nitric oxide stress on rat Islets of Langerhans cells and rat insulinoma cell line (RINm5F) and to determine if cross-linked hemoglobin (Hb-C)could mediate the stress and subsequent apoptosis. The rat cells were treated with a nitric oxide donor SNAP and the DeadEnd™ Colorimetric TUNEL System was used to measure the effect of NO with or without Hb-C. In addition, the cell viability was assessed using the CellTiter 96® AQueous One Solution Cell Proliferation Assay. Twenty-four hours after SNAP treatment, the level of NO2 (a by-product of NO) was measured using Griess Reagent to determine the level of nitric oxide production induced. (3053)
Griess Reagent System
Huang, Z., Tunnacliffe, A.
Notes: Cells were plated in a 96-well plate and incubated until near confluence. The cells were subsequently dried by removing the media before being placed in a humid atmosphere for 2-24 hours. Then the cells were rehydrated by incubating in media for two hours before being assayed for cell viability using the CellTiter 96® AQueous One Solution Cell Proliferation Assay. (3163)
Nabatiyan, A., Krude, T.
Notes: HeLa cells were grown in 24-well plates and transfected with nontarget and p60 siRNAs with untransfected cells as a control. After 24 and 48 hours, loss of cell viability upon silencing of p60 was assessed by incubating the cells with the CellTiter 96® AQueous One Solution Cell Proliferation Assay for five minutes and then stopping the reaction. (3156)
Zhang, C., Ni, X., Konopleva, M., Andreeff, M., Duvic, M.
Notes: Aliquots of 5 x 104 cells/well were distributed in 96-well plates and incubated with 1, 2, and 5 µM novel synthetic oleanane triterpenoid CDDO for 48 hours. Then the relative cell viability was determined by comparing untreated control (DMSO) to treated groups using the CellTiter 96® AQueous One Solution Cell Proliferation Assay. (3164)


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Transwestern brokered the sale of Dorsey Place, an 84-unit, condominium-style apartment building on East University Drive in Tempe, for nearly $15M. San Diego, Calif.-based Stratford Partners and Pathfinder Partners, which had purchased the building in 2011, sold the building to a joint venture between Diversified International Partners and Alliance Residential of Phoenix.
The sellers were represented by Transwestern's multifamily team in Phoenix, led by Vice Presidents Jack Hannum and Bret Zinn and Financial Analyst John Drowns. Diversified International Partners is a fund specifically created for Latin American institutional and qualified high-net worth investors by its general partner, Finesa Real Estate Group, and its fund manager, Transwestern Investment Management.
Built in 2007 as a mixed-use condominium and retail community, Dorsey Place underperformed as a for-sale residential venture, selling only six units to individual owners. After several years struggling through the downturn in the housing market, the team at Stratford Partners stepped in with a new vision for the property, according to Transwestern's Hannum.
"This was Stratford Partners' first acquisition when the company formed in 2011," said Hannum. "It acquired the building at a significant discount to replacement cost and did a fantastic job of stabilizing the asset over the last two years to significantly increase value. Stratford's leadership saw the real potential in Dorsey Place, based on the community's location, the quality of the property and their understanding of the Tempe multifamily market."
Diversified International Partners and Alliance expect additional value can be added to the property through focused, management expertise and by capitalizing on current market expansion. Less than a mile from Arizona State University and in close proximity to major corporate developments now underway in Tempe, the 96,400-square-foot property is a gated, four-story building featuring high-end specifications that distinguish it from newer, for-lease homes.
Dorsey Place has two- and three-bedroom units that feature upscale finishes, including granite countertops and stainless steel appliances. Other amenities include underground parking, a heated swimming pool in a central courtyard and a resident clubhouse.
Alliance and Diversified International Partners plan to reposition Dorsey Place in correlation with the additional commercial developments nearby. Plans include converting the vacant first-floor retail space into additional livable units, adding a fitness center and renovating the existing common area amenities.
"The new capital investment into Dorsey Place will create a highly attractive property that will offer an enhanced living experience to the additional workforce coming into the area," said Alliance Managing Director Paul Engler.
"With State Farm currently building 2MSF of office space on nearby Tempe Town Lake, there is growing demand for multifamily residential units here," said Hannum. "So in terms of timing, this is a win-win for the Dorsey Place buyers and sellers, as well as the City of Tempe."


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A. Weissman
From Uncyclopedia, the content-free encyclopedia
"A. Weissmann once told me, "Learn how to spell you fool!""
Alfred Very Weissman (b. 1959), Born to Burt and Silvia Weissman of Bronx, New York is most known for his monumental works in the field of science, literature, medicine and time travel. One of the only people to win Nobel Prizes in every category, most notably attributed to him are a plethra of famous quotations he had spoken and written over his lifetime. Although it had been mainly accepted by the general public beforehand, it wasn't until he had won his actual court case that the official credit for his accomplishments had actually gone to him.
edit Early Life
edit BirthAlthough no video cameras were around at the time, hospital records have indicated that the first few moments of Weissman's life went somewhat like this: Ahhhhh! Whahhhh! Ahhhhh! Whahhhh! Whaaaaaaaaaaaaaaahhhh! Gurgle. Coo. Gurgle.[1]
edit Childhood
Growing up in a family of 21 Children, the terms "Sharing" and "Discovery Health Channel Special" came up very often in Weissman's Childhood. After jointly graduating from Yale and Harverd Jointly [2] at the age of 7, Weissman found himself spending more and more time at home. This occurred mostly because as he was skipping grades very close to the speed of light, most of the friends Weissman had made existed on planes only visible through insanely immense ammounts of academia, and therefore were in most cases unable to invite him over for very many play dates.
As he spent more time in the home he found that typing was an enjoyable hobby for him. On one evening he wrote out what would come to be known as Othello. On another evening he wrote what would come to be known as the orignal script for the Gene Wilder movie "Silver Streak".
edit Discoveries and Inventions
It took A. Weissman to invent such things as the Lightbulb and the Calculator. Besides those highlights of his inventing carrer, Weissman has also invented many other things used throughout history.[3]
His writings on the concept of gravity and his three laws are what founded the principals many other scientific investigations have been based upon.[4]
edit The Time Machine Incident
The Infamous "Time Machine Incident" occurred on a rainy November 27th 1998. As Weissman was putting the finishing touches on the prototype time machine in his old workshop, he noticed there was a paint crack on the wall on the other side of the room. When walking over to inspect the paintwork of the wall, Weissman slipped on a small puddle of water. As he was falling backwards Weissman inadvertently pushed what happened to be a collection of his life's work and quotes through a moving fan shreading them to pieces. The fan then proceeded to blow the shreads of information into the time machine scattering them throughout time and space.
The Ordeal itself and the insuing court cases to follow left Weissman feeling fairly Verklempt.[5]
edit Court Cases
Due to the controversial time-space paradox matters involved calling most major witnesses during the cases, Weissman would have had a very tough time proving his points. Luckly for him one of the documents to fall back through the time machine was the New York State copyright bill he had authored, and possibly due to The Theory of Extremely Lucky Mishaps landed right on top of the orignal draft of the New York State copyright bill just seconds before it had been signed into law.
Although a few are still pending, all of the finalized court cases have been setteled in favor of A. Weissman. Most major ones still active, Involving Oscar Wilde, have been pursued by Lawyers from the Uncyclomedia foundation.
edit Political Carrer
Although having run for several different offices numerous times, A. Weissman has had a very limited political carrer.
edit A incomplete list of works written/produced by A. Very Weissman
- The Wind in the Willows
- Valley Of the Dolls
- Othello
- "Silver Streak"
- Cheers [6]
- Weissman's New World Dictionary
- Of Mice and Men
- 1984
- Weird Science[7]
edit An incomplete list of Quotes by A. Very Weissman
"Happiness is when what you think, what you say, and what you do are in harmony."
"Envy is the ulcer of the soul."
"What is a cynic? A man who knows the price of everything and the value of nothing."
"If you forget to wear pants, your day will be notably different."
edit Footnotes
- ↑ It Should be noted said Gurgling and Cooing occurred after Weissman was handed off to his Mother
- ↑ Juggling Major Classes in both universities
- ↑ Which I will refrain from mentioning until further court cases are setteled
- ↑ You lost the court case Newton, Get over it!
- ↑ Yiddish. Look it up
- ↑ The Scripts for the television series.
- ↑ The Script for the movie
edit Note
As A. Weissman once said, "Always recognize a good joke."


text:
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TEACHERS from across the district joined over 900 colleagues at the Harrogate International Conference Centre for one of the biggest school training days the region has ever experienced.
The third biennial staff development day event organised by the Red Kite Teaching School Alliance took place on Friday, June 27 and saw staff from Ilkley Grammar School come together with those from Benton Park School in Rawdon, Horsforth School, and Otley's Prince Henry's Grammar School, along with Harrogate Grammar School, Malton School, Nidderdale High School, Ralph Thoresby School, Rossett School, Roundhay School and South Craven School to share best practice.
The Red Kite Teaching School Alliance is a partnership of 24 Yorkshire schools and institutions, across all phases (primary, secondary, special schools and universities) from inner city locations to rural contexts, that come together to share their skills, experience, talent and capacity to help improve the learning and achievement of young people across Yorkshire and the Humber.
The Red Kite Alliance provides nationally accredited and bespoke leadership, training, support, research and development opportunities to school staff across the region. They have a bank of nationally and regionally recognised experts within the Alliance that can act as a task force to help schools and individuals in need of support.
The day gave staff an exciting opportunity to work with colleagues from 11 secondary schools in the partnership across Yorkshire. The theory behind the day was inspired by the marginal learning gains philosophy that underpinned the success of Team GB Cycling at the Beijing and London Olympics: focus on doing a few small things really well; aggregating all these gains together will give staff insightful and practical ideas to implement in their schools, providing a significant impact on teaching and learning.
Attendees were treated to motivational key note speeches from Damian Hughes and Rosie Swale Pope MBE. Damian Hughes is a Professor of Psychology at Manchester University and a former sports psychologist for Manchester United and England Rugby Teams. He works in UK's schools as well as in international business and sport helping to create winning cultures. Global Adventurer Rosie Swale Pope MBE is recognised as one of the world's most courageous women of her generation. She is the only person in history to have undertaken a solo unsupported run around the world over nearly five years.
During the day, groups of staff focused on key central tensions faced in schools, including literacy, numeracy, engaging boys, challenging the most able, and using technology to enhance learning. The outcomes of the discussions were showcased in the afternoon sharing the good ideas and solutions that had been collectively created.
Deputy headteacher for learner experience at Prince Henry's, Judith Nelson, said: "As a school within the Red Kite Alliance, the benefits of this cross-region collaboration are clear.
"Although we run several very effective training days in school throughout the year, being able to work with such a large group of professionals and gain knowledge and best practice from across the region is extremely valuable.
"The lessons we take from the day and the networks which are built are of immense benefit."


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Posey, Panda back Bumgarner's great start
Left-hander strikes out 12, contributes RBI as Giants win nightcap
CHICAGO -- The triumphant pounding of Madison Bumgarner's left fist into his glove after he struck out Javier Baez to end the seventh inning echoed the constant report of the Giants' bats Thursday night.
Bumgarner, Buster Posey and Pablo Sandoval were most responsible for the raucous 5-3 verdict that gave the Giants two victories in the series' three games -- a tangible accomplishment, given the adverse weather that disrupted routines and bedtimes for both clubs.
Bumgarner displayed his wealth of skills, striking out 12 -- one short of his career high -- while working seven innings. He was particularly rough on Baez, Chicago's hotshot rookie, who struck out four times. Bumgarner (14-9) recovered after yielding three first-inning runs on back-to-back homers, blanking Chicago on four hits afterward. For good measure, he added a fourth-inning RBI single off his Cubs counterpart, Travis Wood (7-11).
Bumgarner explained that his expressive reaction reflected his desire to excel.
"We have to win all the games we can win right now and that could have been the turning point in the game, depending on what happened there," he said. "He was probably my last hitter, so I gave it everything I had to get us back to the dugout."
Welington Castillo, who struck out twice after hitting the second homer off Bumgarner, vouched for the left-hander's effectiveness.
"He just challenged us with fastballs, and I think we were a little aggressive with him," Castillo said. "I think after the first inning he figured out that we were aggressive and he kept throwing that high fastball."
Earlier Thursday, the Giants dropped a 2-1 decision to the Cubs in the completion of Tuesday's suspended game.
The Giants will encounter their next challenge in Washington, where they'll open a three-game series against the Nationals, winners of 10 consecutive games. As daunting a task as that is, at least the Giants left Wrigley Field knowing that the heart of their batting order maintains a robust beat.
Posey and Sandoval, who hit third and fourth, respectively, combined for five extra-base hits and three RBIs. Both entered Thursday with statistics that would satisfy many a ballplayer. But observers expect more from Posey, the 2012 National League Most Valuable Player, and Sandoval, the World Series MVP that year.
With 35 regular-season games left, ample time remains for Posey and Sandoval to propel the Giants into the postseason.
Sandoval made authoritative contact all night as he went 3-for-4 with a pair of doubles and drove in the Giants' first two runs.
Posey went 4-for-4, hitting his 14th homer of the season to break a 3-3 tie in the fifth inning and lacking a triple for the cycle.
"We've got to have him," Bumgarner said, "and we've got to have everybody else to get where we want."
The outcome gave the Giants five wins in their last seven games and left them a half-game in front of Atlanta for the league's second Wild Card spot and 3 1/2 games behind first-place Los Angeles in the NL West. But Giants manager Bruce Bochy didn't reveal which postseason berth he considered to be most attainable.
"We're still in August. There's a lot of baseball left," Bochy said. "I don't think at this point you target a Wild Card or [a division title]. I don't think any club should."
At this juncture, simply winning is the paramount objective.
"It's definitely not the time of year to hold back," Bumgarner said.
Nothing restrained Posey, who felt refreshed after resting a stiff right hip Wednesday.
"The hip is something I've kind of battled throughout the year. I've had it for a while," he said. "It just kind of gets you bound up, is the best way to describe it. Everything gets kind of tight around my hip and back."
Those who vote for the Silver Slugger awards, which go to the top hitters at each position, might want to study this game. As baseball's most productive pitchers at the plate, Bumgarner (.269 batting average, .304 on-base percentage, .481 slugging percentage, three homers, 12 RBIs, nine runs) and Wood (.261/.306/.500, three homers, 10 RBIs, eight runs) entered the affair with remarkably similar statistics.
Yet their paths diverged sharply as the evening unfolded. Though Wood struck out Bumgarner twice, in between those at-bats the Giants left-hander followed Joaquin Arias' one-out double in the fourth with a ringing single to left field that tied the score.
Chris Haft is a reporter for MLB.com. Read his blog, Haft-Baked Ideas, and follow him on Twitter at @sfgiantsbeat. This story was not subject to the approval of Major League Baseball or its clubs.


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TAMPA, Fla. – The Saint Leo University men's swim team put up a valiant fight, but were unable to defeat the eighth-ranked University of Tampa Spartans on Saturday morning at the University of Tampa Aquatic Center.
Patrick Ceddia led the way for Saint Leo, earning two first place finishes on the morning. The senior took home the top slot in the 1000 Yard Freestyle with a time of 9:52.06, and continued his success into the 500 yard Free event where he earned a time of 4:48.62.
Dylan Kasson finished behind Ceddia in the 500 Free, touching with a time of 4:54.96, good for second place. Kasson also earned a fourth place time of 1:48.17 in the 200 Yard Freestyle event, finishing behind Milton Alberto-Requejo who earned a third place time of 1:45.06.
Alberto-Requejo picked up a second place touch in the 100 Yard Free, hitting the wall with a time of 47.04.
Matheus Assis closed out the 50 Yard Free event with a first place time of 21:04, before moving on to pick up a second place touch in the 100 Yard Butterfly with a mark of 51.56.
Pawel Trenda took home first, second, and third place times on the morning. Trenda started his day with a third place time of 53.52 in the 100 Yard Backstroke, and followed with a second place performance in the 200 Yard Backstroke with a mark of 1:53.78. the Oswiecim, Poland native closed out his day with a top finish in the 200 Yard IM, earning a time of 1:57.30.
Other notable individual finishes on the day came from Vashaad Fincher, who picked up a second place finish in the 100 Yard Breaststroke, followed immediately by Jose De Jesus in third with a time of 1:02.42. McClellan Lowry took home third in the 200 Yard Butterfly, earning a time of 2:02.17.
The Lions opened the day with a second and third place showing in the 200 Yard Medley Relay. The "A" squad of Trenda, Fincher, Assis, and Alberto-Requejo finished with a total time of 1:35.40, followed immediately by the combination of Rhet Rheinlander, De Jesus, Gabe Keown, and Ceddia with a time of 1:36.25.
To close out the meet, Saint Leo took home a first place time of 3:06.45 in the 400 Yard Freestyle Relay thanks to top performances by Alberto-Requejo, Keown, Ceddia, and Assis.
The Lions return to the pool deck on Saturday, December 14, when they travel to Ft. Lauderdale, to participate in the four-day Nova Southeastern Invitational.
For the latest news, updates, and information on the Saint Leo women's swim team, be sure to visit SaintLeoLions.com. Fans can also stay up-to-date on the latest Lions news by following Saint Leo Athletics on Facebook, Twitter, Instagram, and Youtube.


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TCNJ's Solar Splash team came back with numerous awards in the Intercollegiate Solar Splash Competition held in Cedar Falls, Iowa. The team was assembled as a senior project and consisted of team members Glen Reese, Steve Voinier, Steve Stockhamer, Chris O'Mullane, Patrick Dougherty and advisors Dr. Norman Asper, Anthony Deese, and Karen Yan.
This year's team designed their boat around a previous year's hull. Special features of their design included fabrication of a custom propeller that was machined on TCNJ's new five axis CNC machine, a new peak power transfer system, new solar panels complements of Schott Solar, and a robust storage system that allowed for maximum boat buoyancy in case the boat filled with water. "The project required a lot of time and effort" Patrick said, "but that helped to make the competition as fun and enjoyable as it was."
The competition spanned five days and consisted of three events, endurance, sprint and slalom. The endurance event tested the boat's power efficiency and use of solar power; the sprint event raced each boat to 300m; the slalom event tested the boats' maneuverability. Teams were also judged on visual display, technical report, qualifying time, hull design and workmanship. TCNJ came back with 4th place in the overall competition, 3rd in slalom and for their technical report, 5th in sprint, and won awards for Outstanding Hull Design and Outstanding Workmanship.
Information and pictures from the competition of the team can be found on Solar Splash's website and TCNJ Solar Boat.


text: TV and Radio Interviews: Fr. Frank Discusses HHS Mandate with Jay Sekulow MEDIA Media Home Priests for Life Podcasting Send a question forour Media Mailbag Challenge the Media:Show an Abortion! This Week's Media Schedule Promote Our Programs! Priests for Life Online Video YouTube Facebook Priests for Life Television Priests for Life Radio Fr. Frank's Bi-weekly Columns Press Releases News Archive OTHER SECTIONS America Will Not Reject Abortion Until America Sees Abortion Prayer Campaign Take Action Social Networking Rachel's Vineyard, A Ministry of Priests For Life Silent No More Awareness Campaign, A Project of Priests For Life Clergy Resources SIGN UP FOR EMAIL TV and Radio Interviews Loading the player... Tweet Audios OnlyVideos OnlyAll Fr. Pavone on Patchwork Heart Radio (July 26, 2017) Fr. Frank on Don Kroah: Healthcare Reform (July 2017) Alveda King on EWTN's Morning Glory (July 19, 2017) Fr. Frank Pavone on "From The Median" (May 15, 2017) Fr. Frank interviewed by Terry Barber and Jesse Romero (May 2017) Fr. Stephen Imbarrato on In Season and Out of Season (April 21, 2017) Kevin Burke on Relevant Radio 1430 "Morning Air" (03/16/2017) Janet Morana on EWTN Open Line (02/28/17) Janet Morana talks to Joan Lewis about Norma McCorvey (Vatican Insider, Feb 25, 2017) Fr. Frank Pavone on The Proverbial Lawyer - October 22, 2016 Fr. Frank Pavone on Issues, ETC discussing the extinction of pro-life Democrats - Sept 2016 Fr. Frank Pavone on Moody Radio: Can a Pro-Life Person Vote for Pro-Choice Candidate - Sept 2016 Fr. Pavone on the Drew Mariani show - September 13, 2016 The Hard Line: Fr. Pavone discusses the risk religious leaders face from ISIS Father's Day Interview about Men and Abortion - Kevin Burke on Point of View - June 16, 2016 Fr. Frank on Mater Dei Radio with Dina Hale - June 7, 2016 Fr. Frank on "A Closer Look" on Relevant Radio - May 16, 2016 Evangelist Alveda King and Rev. Dr. Alfonso Espinosa - May 7, 2016 Evangelist Alveda King on the Derrell Day Show - May 6, 2016 ONE on ONE with Dr. Alveda King Fr. Frank Pavone on Relevant Radio with Drew Mariana Part 1 - April 29, 2016 Fr. Frank Pavone on Relevant Radio with Drew Mariana Part 2 - April 29, 2016 Protest Planned Parenthood: Fr. Frank Pavone on WSFI Catholic Radio - April 20, 2016 Dr. Theresa Burke on the Bob Dunning Bishop's Radio Hour - January 2016 Fr. Frank Pavone on Kevin McCullough Show, with guest host Pastor Dave Watson - November 4, 2015 Fr. Frank Pavone on Jensine Bard Show Part One (October 6, 2015) Fr. Frank Pavone on Jensine Bard Show Part Two (October 6, 2015) WSFI Report from World Meeting of Families: Fr. Frank Pavone - September 2015 Fr. Frank Pavone on Wallbuilders: Planned Parenthood Videos (September 15, 2015) Fr. Frank Pavone on Eagle Forum with Phyllis Schlafly Part 1 - September 2015 Fr. Frank Pavone on Eagle Forum with Phyllis Schlafly Part 2 - September 2015 Fr. Frank on Mater Dei Radio - July 20, 2015 Fr. Frank Pavone on Catholic Connection with Teresa Tomeo - July 14, 2015 Fr. Frank on Mater Dei Radio - July 13, 2015 Fr. Frank on Mater Dei Radio - July 6, 2015 Fr. Frank on WallBuilders talking about RU-486 Reversal - June 9, 2015 Fr Frank Pavone on Mater Dei Radio in Oregon - April 27, 2015 Reversing Regret: Procedure Stops Abortion in Progress Special Presentation: Interview with Fr. Frank Pavone on WSFI - August 4, 2014 Dr. Alveda King: Black History Month Boycott (Carl Jackson radio show, February 2014) Fr. Frank on Bott Radio Network - January 5, 2014 Fr. Frank interviewed by Pastor Dave Watson - January 4, 2014 Janet Morana on Wallbuilders talking about Recall Abortion - December 27, 2013 Saying goodbye to the child we never met Fr. Frank and Janet Morana on Archdiocese of Chicago Life Talk Alveda King and Mike Huckabee reflect on the 50th anniversary of MLK's I Have a Dream speech Dr. Alveda King on the Tom Roten Radio Show, July 16, 2013 April 28, 2013: Fr. Pavone on The Palin Update with Kevin Scholla talking about Gosnell Fr. Frank on Wallbuilders April 23, 2013: Pro-Life Graduates February 26, 2013: Janet Morana talks to Janet Parshall about Recall Abortion Fr. Frank Discusses HHS Mandate with Jay Sekulow Fr. Denis Wilde, O.S.A. on Holy Family Radio Fr. Frank as Guest Host of the Drew Mariani Radio Show Fr. Frank as Drew Mariani's Guest Let the Fire Fall Let the Fire Fall Catholic Answers Live (12/11/06) Catholic Answers Live (10/20/06) Catholic Answers Live (08/21/06) Dr. Tony Levatino on Catholic Answers Live (06/23/06) Catholic Answers Live (06/23/06) Catholic Answers Live - Part One (04/21/06) Catholic Answers Live - Part Two (04/21/06) Show the Truth - Catholic Life with Dina Marie Hale (10/21/05) Living Bread Radio Interview (07/09/05) Sharing the heart of the Christian Faith - Part 1 Sharing the heart of the Christian Faith - Part 2 Sharing the heart of the Christian Faith - Part 3 Fr. Wilde on In His Sign Network: Euthanasia (05/24/99) Putting it on the Line: The Effects of Abortion in our Lives (05/10/99) HOME - PRAYER REQUESTS - QUESTIONS & COMMENTS Priests for Life PO Box 141172 • Staten Island, NY 10314 Tel. 888-735-3448, (718) 980-4400 • Fax 718-980-2542 firstname.lastname@example.com


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Panda stuns D-backs with ninth-inning blast
Bumgarner contributes seven shutout frames to dramatic victory
PHOENIX -- Positive thinking resulted in power for Pablo Sandoval, whose titanic two-run homer erased a ninth-inning deficit Tuesday night and propelled the Giants to a dramatic 2-1 triumph over the Arizona Diamondbacks.
File this one under non-fictional fairytales. Sandoval essentially predicted that he would do something to wipe out Arizona's 1-0 lead when he batted with Angel Pagan on second base and one out.
As right fielder Hunter Pence related, he delivered an urgent yet encouraging message before Sandoval headed for the batter's box to face D-backs closer J.J. Putz.
"Pablo, feel that good 'click,' that good connection. Click him," Pence recalled saying. That prompted Sandoval to begin repeating the title of the song "Clique" by rapper Kanye West.
Said Pence, "He kind of nodded his head like, 'I'm going to do it.' I just tried to plant the seed of a good connection. He made it happen."
Asked if he called his shot, Sandoval grinned and replied, "Pretty much."
Sandoval pretty much crushed Putz's 0-1 sinking fastball off an auxiliary scoreboard in right field for his fourth home run of the season. He has 11 hits in his last 18 at-bats, a .647 binge.
As Sandoval returned to the dugout, he triumphantly bellowed, "I told you so!" as he slapped palms with Pence, who stood in the on-deck circle.
This was a typical Giants-D-backs conclusion. In five meetings, they've played two extra-inning games and three one-run decisions. San Francisco's three victories have been come-from-behind verdicts.
"That's what baseball's about, dude," Pence said. "These games against Arizona have been unbelievably close, incredible baseball battles. It's like the smallest things go the longest ways."
Kind of like Sandoval's homer. After fouling off Putz's first sinkerball, Sandoval demonstrated his rapidly developing plate discipline by urging himself to calm down and wait for a good pitch to hit -- one of baseball's most time-honored mantras.
"The first pitch, I tried too much," Sandoval said.
The second pitch was good for Sandoval, but not for Putz.
"It just seems like every time I leave one of those up, it's getting crushed right now," said Putz, who has blown four of nine save opportunities.
The Giants ended April with a 15-12 record, comparing favorably with their first-month starts in their pair of World Series seasons (13-9 in 2010, 12-10 in 2012).
Considering the starters' mediocre 4.15 ERA and the spate of defensive mistakes that accompanied the club's recent five-game losing streak, manager Bruce Bochy felt satisfied with the Giants' break from the gate.
"It shows you a little bit about the mettle and character of the club, to be where we are despite not having played as good of ball or pitched like we normally do," Bochy said. "The defense hasn't been as solid as it might be. Because of how hard we fight, we're fortunate to have a winning record."
Personifying that determination, Madison Bumgarner yielded three hits in seven innings. He had the misfortune of pitching on the same night that Arizona's Trevor Cahill limited the Giants to three hits in eight innings before Pagan's single christened the ninth and prompted Putz's entrance. Josh Wilson's eighth-inning homer off Santiago Casilla accounted for the only scoring to that point. It was Wilson's first Major League homer since June 5, 2011, and 10th in 1,043 Major League plate appearances since 2005.
"He could have five wins," Bochy said of Bumgarner. "We're not getting a lot of runs for him, but he's doing what we need, and that's putting up zeroes for us."
Sandy Rosario finished the eighth inning for Casilla by recording one out. That gave the decision to the rookie right-hander, who'll likely return to Triple-A when either Jeremy Affeldt leaves the disabled list or Jose Mijares returns from bereavement leave. It marked the second game in a row in which a Giants pitcher secured his first career victory; 31-year-old rookie Jean Machi earned that distinction on Monday. Sergio Romo pitched a perfect ninth for his 10th save in 11 chances.
Chris Haft is a reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.


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The new OS X Gatekeeper encourages desktop apps to be registered with Apple, with users warned against installing unsigned software unless they disable the prompts.
The benefits—and the potential pitfalls—are obvious. It's intended as as an anti-malware system (with a whitelist rather than a blacklist), and the registration process will be simple and inexpensive. It'll destroy the nascent market for sleazy Windows-style antivirus subscriptions.
On the other hand, it's under the OS vendor's control, and once established, offers it certain temptations. Will Apple use it to anti-competitively influence the desktop software market? Will OS X end up as closed to unapproved developers as iOS? Will the controls end up co-opted by governments? Read the rest


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Perfectly easy to use, this plug in light features an on/off switch on the backplate. Installs easily, plugging into any standard wall outlet. Brushed steel finish. Matte black finish backplate. White cotton and polyester blend fabric. From the Possini Euro Design® lighting collection.
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Red Roof Inn Tulsa Airport
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Colorful Avocado Salad Recipe
I appreciate the crisp, fresh vegetables and bright colors in this nutritious salad. A friend gave me the idea for this recipe while we were discussing salads. —Bev Lehrman, Gijoca, Brazil
- 1 medium tomato, cut into eighths
- 1/2 small cucumber, peeled and thinly sliced
- 1 small red onion, halved and thinly sliced
- 1/3 cup julienned green pepper
- 2 tablespoons Italian salad dressing
- 1 medium ripe avocado, peeled and cubed
- 1. In a small bowl, combine the first four ingredients. Add dressing and toss to coat. Chill until serving. Just before serving, add avocado and toss gently. Yield: 2 servings.
Nutritional Facts
3/4 cup: 190 calories, 14g fat (2g saturated fat), 0 cholesterol, 228mg sodium, 17g carbohydrate (5g sugars, 8g fiber), 3g protein.
Reviews for Colorful Avocado Salad
Average Rating
Reviewed May. 21, 2012
"Wonderfully simple dish that my whole family loved. I usually make it a day before I plan to serve it so all the flavors have time to mesh."
Reviewed Feb. 24, 2012
"Made as directed and this turned out really good. Next time I might decrease the red onion though. Will def make again, Thanks!"
Reviewed Nov. 7, 2010
"This was extremely good. Crunchy and very flavorful. I added sea salt and fresh pepper for some additional flavor. Great with steak or tri tip."
© 2017 RDA Enthusiast Brands, LLC


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Aside from being painfully chic – what with its "winter white" moniker and all – this recipe is a particularly sentimental one for me as it's one of the first things my now husband made for me when we first started dating.
You see we both went to culinary school – met there in fact – but he took the road less kitchen-y in favor of other aptitudes (basically, he's a fantastic marketer and a terrible cook [his words not mine]). Keeping a few culinary tricks up his sleeve, though, he loves making chili and, being that we started dating mid-winter, this recipe has always been a big ol' seasonal heart-warmer for me.
We call it a white chili because there's very little tomato in it, but the addition of cumin, beer, tons of beans and a topper of creamy avocado keep it just as satisfying as a traditional red chili. It's a nice change to help wean you off from the football season barrage.
And take it from a culinary school grad who (claims that he) can't cook. This recipe is super flexible, welcoming into the pot whatever vegetables you have in the house, and is delicious with the addition of a chopped up sweet potato or chipotle in adobo.
Just make sure to serve it in something chic to keep the momentum going for me, would you please?
Winter White Turkey Chili
Yield: 4 to 6 servings
Prep Time: 5 minutes
Cook Time: 40 minutes
Active Time: 45 minutes
1 tablespoon olive or vegetable oil
3 to 4 slices thick-cut bacon, chopped
1 1/4 pounds ground turkey (all lean or a mix, whatever you prefer)
1 large sweet onion, chopped
1 large red bell pepper, seeded and chopped
2 stalks celery, chopped
2 to 3 cloves garlic, finely chopped
1 teaspoon ground cumin
1 tablespoon chili powder
1 (14-ounce) can chick peas, drained and rinsed
1 (14-ounce) can small white beans, drained and rinsed
1 (14-ounce) can diced tomatoes
1 (4-ounce) can fire-roasted green chilies
1 (12-ounce) bottle light beer, such as lager or ale
1 tablespoon Worcestershire sauce
Salt and ground black pepper
Fresh cilantro, to garnish
Ripe avocado, chopped, to garnish
Place a large pot over medium heat with the oil. Add the bacon to the pot and cook, stirring occasionally, until browned, 5 to 6 minutes. Increase the heat to medium-high and then add the turkey, onion, bell pepper, celery, garlic, cumin, and chili powder to the pot. Cook, stirring frequently, until the vegetables are tender, about 10 minutes.
Add the remaining ingredients to the pot and season with salt and pepper. Reduce the heat to medium and simmer the chili, stirring occasionally, until the liquids have thickened and the chili is very aromatic, about 20 minutes.
Serve the chili garnished with chopped cilantro and avocado.
Note: I find there are two schools of thought when making chili – "to brown the meat or not to brown the meat?". As you'll see here, I prefer not to brown the meat ahead of time – I just add it in with the vegetables. Neither method is right or wrong, I just feel you get a more tender finished product when the meat cooks more gently along with the vegetables. It's also easier to break up into smaller pieces so that you don't end up with a giant hunk of cooked ground turkey on your spoon.
I also opt not to take the bacon out after it has been browned – I want to simmer that bacon flavor in with the chili. You could certainly take the crisped bacon out of the pot if you wanted to and reserve it to be a crispy garnish for serving.
Patrick W. Decker's life revolves around food. Always has, probably always will. As a graduate of The Culinary Institute of America and past member of the culinary teams for Food Network stars like Rachael Ray, Sandra Lee and Paula Deen, he now works as a food stylist and producer in NYC by day and a food writer and recipe developer at his home in New York's Hudson Valley by night. You can see what he's up to by following his latest tweets on Twitter at @patrickwdecker or visiting his website at patrickwdecker.com.