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US stocks gained while Treasuries trimmed an earlier advance as the House voted to temporarily suspend the the federal debt limit. The yen climbed for a third day after the Bank of Japan deferred new monetary stimulus.
The Standard & Poor's 500 Index added 0.1 per cent to 1,494.37 at 1:26 p.m., while a rally in International Business Machines Corp. drove the Dow Jones Industrial Average up more than 75 points to above its best closing level since October 2007. Ten-year note yields decreased one basis points to 1.83 per cent. Japan's currency rose 0.2 per cent to 88.55 per dollar, poised for its first three-day increase since November. Portugal's 10-year yield slid as the nation prepared to return to the bond market.
The House voted 285-144 to lift the nation's debt ceiling through mid-May as a Bloomberg poll showed global investors say the state of the American government's finances is the greatest risk to the world economy. The International Monetary Fund cut its global growth forecasts and now projects a second year of contraction in the euro region as progress in battling Europe's debt crisis fails to produce economic recovery.
"We are still pretty constrained by the range and the debt-ceiling debate," said Larry Milstein, managing director in New York of government-debt trading at R.W. Pressprich & Co. "We are clearly closer to the bottom of the range, 1.75 to 2.05 per cent on the 10-year. We may test the lower ends of this range."
Debt Ceiling
Thirty-year bonds held two days of gains, with the yield little changed at 3.03 per cent, as the Federal Reserve purchased $US1.474 billion in longer-term debt. Inflation expectations dropped from the highest in almost three months as the US prepares to sell $US15 billion in 10-year inflation-indexed debt tomorrow.
The House voted to suspend the government's $US16.4 trillion borrowing limit until May 19, when the measure would allow the US's borrowing authority to automatically be increased to accommodate the amount the Treasury borrowed during those three months. Republicans plan to use two other approaching deadlines, the March 1 start of automatic spending cuts and the need to pass a bill to fund the government by the end of March, to extract spending reductions.
The debt ceiling "is a risk that is constantly weighing," said Bernard Delattre, president of Altimeo Asset Management in Paris. "It can bring volatility to the market in the short term."
Market Movers
In the stock market, technology shares rose 1.3 per cent as a group for the biggest gain in the S&P 500 as eight of the 10 main industries retreated. IBM surged 5.1 per cent to $US206.02, the biggest jump since July 2011, after the world's biggest computer-services provider forecast profit that exceeded analyst estimates. The gain in the IBM, which accounts for almost 12 per cent of the price-weighted Dow, added more than 76 points to the 30-stock average, leaving it up 68.89 points at 13,781.10 even as 17 stocks in the measure retreated.
Google Inc. rose 6.4 per cent, the most in more than a year, after the profit topped analysts' estimates as advertisers boosted spending to reach consumers during the holidays.
Apple Inc. climbed 1.4 per cent before the largest company by market value reports results after the close of US trading today, with analysts forecasting the first drop in profit in a decade. Fiscal first-quarter net income slipped 2 per cent to $US12.8 billion, or $US13.48 a share, according to analysts' estimates compiled by Bloomberg. In all except one quarter since 2003, profit has jumped more than 10 per cent. Analysts project sales will rise 18 per cent to $US54.8 billion, the slowest growth rate since 2009.
Earnings Season
Per-share earnings have exceeded analysts' projections at about 76 per cent of the 101 companies in the S&P 500 that have released results so far, data compiled by Bloomberg show. Profits at companies in the index are forecast to exceed $US1 trillion this year, according to more than 11,000 analyst estimates compiled by Bloomberg. Earnings have grown 20 per cent for the group amid a 4.5 per cent increase in sales. More than 30 companies in the S&P 500 are reporting today.
Among European stocks, TUI AG and TUI Travel Plc fell more than 4.8 per cent as the former retreated from a plan to combine with the latter, a week after the two travel companies said they were in preliminary merger talks.
Novartis AG, Europe's biggest drugmaker, climbed 4.1 per cent after reporting earnings that beat projections and saying Chairman Daniel Vasella will step down. Unilever gained 2.4 per cent as the world's second-largest consumer-goods maker reported faster-than-estimated revenue growth.
IMF Forecasts
The world economy will expand 3.5 per cent this year, less than the 3.6 per cent forecast in October, the Washington-based IMF said today in an update of its World Economic Outlook report. While the fund projects growth this year increasing from last year's 3.2 per cent pace, it expects the 17-country euro area to shrink 0.2 per cent in 2013, instead of growing 0.2 per cent as forecast in October.
"Is Europe on the mend? I think the answer is yes and no," IMF Chief Economist Olivier Blanchard said in a video released with the report. "Something has to happen to start growth."
The yen strengthened against all 16 major counterparts, gaining 0.2 per cent per euro. Europe's shared currency lost 0.1 per cent $US1.3315.
'Upward Correction'
The yen will weaken against the US currency by the end of the year, as the BOJ's decision to hold off on fresh stimulus puts pressure on the government to revive growth through fiscal measures, according to a Bloomberg survey of strategists.
"The yen currently is in an upward correction phase after it weakened rapidly in the past two months," said Noriaki Murao, managing director of the marketing group at Bank of Tokyo-Mitsubishi UFJ Ltd. in New York. "The market was somewhat disappointed in that no deadline has been set for the inflation target and that the open-ended asset purchases don't start until 2014."
Japan's top currency official, Takehiko Nakao, said the central bank isn't engaged in a competitive devaluation of the yen, pushing back against international criticism of the nation's monetary policy.
"The BOJ's monetary policy, decided yesterday, is aimed at ending persistent deflation, so criticism that it's a form of competitive devaluation is misplaced," Nakao, the Vice Finance Minister, said in an interview in Tokyo today.
The MSCI Emerging Markets Index fell 0.2 per cent. South Korea's Kospi Index slipped 0.8 per cent as Goldman Sachs Group Inc. cut its economic growth forecast. India's Sensex index gained 0.2 per cent, Russia's Micex Index slipped 0.2 per cent. The Shanghai Composite Index added 0.3 per cent before a manufacturing report tomorrow.


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A Yorkshire surgeon has been appointed to the role of executive medical director at Airedale NHS Foundation Trust.
Karl Mainprize was formerly deputy medical director at York Hospitals NHS Foundation Trust.
His role, in addition to being a member of the board, will be as the trust lead for quality and safety and clinical and information governance. Ensuring patient safety, care and experience is a priority. He will also provide professional leadership for clinical staff and managing medical education and training as well as developing relationships with commissioners and regulators.
Karl said: "I am delighted with my new appointment and I am looking forward to working closely with my new colleagues to enhance the services "Airedale provides to commissioners and for the local community. I am interested in developing technology to improve communication with patients and multidisciplinary teams and believe we can design our service around patients' needs."

subset: commoncrawl


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A criminal gang carefully disguised more than $400 million worth of the street drug ice among cleaning products bound for Sydney from China, after testing the way with a run of dummy shipments.
Even X-rays might not have picked up the record haul, which exceeded half a tonne of highly addictive methamphetamine.
But a sharp-eyed member of the public saw something suspicious at a warehouse in West Ryde, in Sydney's northwest, and the high-stakes smuggling attempt was over.
After an investigation sparked by that tip-off, police arrested a Sydney university student and two Asian nationals who now face charges carrying the severest penalty. The seizure amounted to 585kg of methamphetamine with an estimated street value of $438 million.
"None of it would have happened if it wasn't for one phone call from the community," NSW Police Commissioner Andrew Scipione told reporters at a media conference on Thursday.
Police received the tip off in September last year, and in February the Joint Organised Crime Group (JOCG), involving state and federal authorities, detected a number of dummy shipments in overseas shipping containers organised by the syndicate.
"There were a number of dry runs, we'll allege, that this syndicate have brought into Australia to test the procedures of customs and police," AFP Commissioner Tony Negus told reporters.
The drug was found last week in a single container that originated in southern China, hidden inside six one-tonne bags of cleaning supplies.
Specialist officers replaced the drugs with the same quantity of an inert substance and allowed the shipment to continue to a storage facility at Regents Park, in Sydney's southwest.
"Our forensic people do a very good job of making it look like it's the real thing," Mr Negus said.
On Wednesday, undercover officers watched three men unloading the mock substance and arrested them as they left.
All three were charged with various offences that carry a maximum penalty of life imprisonment and/or a fine of $1.2 million.
Hong Kong national Cheung Tuen, 51, and Singaporean national Boon Cheng Leow, 32, appeared in Central Local Court on Thursday and did not apply for bail, which was formally refused.
University of Western Sydney IT student Tony Ming Ly, 21, had his bail application refused.
The Australian citizen allegedly hired a Toyota van that was intended to transport the drugs, the court was told.
Officers found a GPS device inside which led them to an address where police found 18kg of iodine, a substance used to make ice.
All three men will come before the same court on May 8.
Police also raided properties at Regents Park, Bexley North, Wakeley, Canley Heights, Beverly Hills and Ryde.
A clandestine drug lab was found at one of the premises, but police believe the imported product they seized was ready for street distribution.
The AFP has not ruled out further arrests in relation to the syndicate and is communicating with Chinese authorities.
Customs chief executive Michael Pezzullo said 85 per cent of detected drug importations originated from intelligence gathering.
"If you're just relying on x-ray screening, for instance, you wouldn't necessarily pick it up," Mr Pezzullo said at the media conference.
Premier Barry O'Farrell congratulated police, telling parliamentary question time he was "absolutely in awe of the work the NSW police do".
Federal Home Affairs Minister Jason Clare said the operation was "a great example of teamwork".
"It demonstrates what we can achieve when we work together," Mr Clare said in a statement.


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Georgian (mxedruli)
If you've spotted anything on Omniglot that needs correcting, or have any suggestions for new material or how the site could be improved, this is the place to discuss them.
4 posts • Page 1 of 1
Georgian (mxedruli)
The five letters in red that aren't in use today, I was thinking that maybe you can also add the their pronunciation too, instead of having just a '-'?
Re: Georgian (mxedruli)
I've added the names of those letters to the Georgian letter chart.
one language is never enough / 一種語言永遠不夠 / dydy un iaith byth yn ddigon
Re: Georgian (mxedruli)
Oh btw, on the useful phrases in Bulgarian, it should be Воистину воскресе and not Воистина, a lot of people get that wrong, it's an archaic saying utilizing cases we've long dropped.
Re: Georgian (mxedruli)
Saimundo wrote:I've added the names of those letters to the Georgian letter chart.
Cool, maybe can add the pronunciation too:
ჱ [ɛi̯]/[ɛj]
ჲ [j]/[i̯]
ჳ [wi]
ჴ [qʰ]
ჵ [oi̯]/[oj]
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text:
Add a glamorous Art Deco touch to your wedding cake with today's simple but stunning cake topper DIY.
Here's what you'll need:
- Styrofoam ball, 3.5″
- 4″ clear plastic prism picks (we found ours online at a restaurant supply store)
- Metallic gold craft paint
- Metallic gold spray paint
- One wood kabob skewer (cut in half)
Step 1: Cut
Cut a styrofoam ball in half with a sharp knife to make sure you have a smooth, flat half dome.
Step 2: Paint
Paint the styrofoam ball with gold metallic paint and let it dry for a few hours.
Step 3: Spraypaint
Lay out about 100 plastic prism picks and spray paint evenly to make sure all edges are covered. Flip them over and spray any unfinished sides.
Step 4: Assemble
Stick the prism picks in the styrofoam in an organized pattern at first, and then fill in any gaps as you see fit.
Step 5: Top it Off
Stick the wooden skewer into the flat side of the dome. Then, place the cake topper on the top of your wedding cake (making sure the styrofoam is very slightly elevated from the top of your cake and not touching). Get ready for a dazzling finish!
If you try this idea yourself, or if you have any DIY ideas to share, send your photos to email@example.com and we'll post them for all of our fans and followers.


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ORLANDO, Fla. - The parents of the teenage girl who remains in a coma after being shot in crossfire while leaving an Orlando church last year testified on Tuesday in her accused shooter's trial.
Opening arguments began on Tuesday in the trial for 20-year-old Tyrone Mosby, who's charged in the shooting of 16-year-old Danielle Sampson.
Danielle's parents, Alma and Justin Fletcher, testified on Tuesday that they were driving home when they heard a series of loud bangs. When he heard the bangs Justin Fletcher told his family to "get down" and then pulled over. At first neither of the Fletchers realized that Danielle was hurt, they told jurors.
After calling her name several times, Alma Fletcher said she realized something was wrong because her daughter, who was laughing and watching a DVD in the backseat, now wasn't moving or answering questions.
Also testifying on Tuesday was Mosby's intended target, Chester Joseph, according to the state. Joseph said that after catching Mosby robbing his house, he tried to chase Mosby down and that's when Joseph said Mosby started shooting at him.
"If he hadn't a hit that little girl, if he would have just shot at me we wouldn't be here right now. I wouldn't have called the police. Period. I would have just handled it the street way," Joseph said on Tuesday.
The defense said Joseph can't be trusted because he is a convicted felon with a house full of drugs and that Joseph has changed his story several times and is trying to protect himself.
"Let me tell you I lied a lot. I lied a lot," Joseph said. "But when I told the truth, the truth was the truth."
Jurors were selected on Monday as Danielle watched from a conference room.
Danielle was 15 years old and a sophomore at Apopka High School when she and her family got caught in crossfire as they left church July 29 in their van. Danielle was shot in the head by a stray bullet and now has severe brain damage.
Police said Mosby, who was 19 at the time of the shooting, was one of several people who had burglarized a home and shot at the homeowner as they ran away.
If found guilty, Mosby faces up to life in prison.
Copyright 2013 by ClickOrlando.com. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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Cedar City Home Remodeling Contractor - Holyoak Homes Cedar City Home Remodeling… st george
- Publish Date: 11-05-16
Preconstruction: Designs-Planning-Conception Take your dream home from Conception to Reality. Choose from one of our plans or we will collaborate our ideas with your ideas to design your perfect custom dream home. Exterior and Interior Designs : This…Read more


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Boot Barn Item #: 2009781
Color: Click a button belowcolor
size: Click a button below Size Chartsize
- 97% cotton 3% spandex
- Long sleeves
- Solid print
- Embroidered detail along yokes, back, and pockets
- Rhinestone details
- Double front pockets with flaps and snaps
- Snap down placket
- Front and back western yokes
- Machine wash cold with like colors inside out on gentle cycle
Bring on summer with funky colors and modern western charm. This Embroidered Western Shirt by Rock 47 is perfect for the modern cowgirl. The simple design with solid color is elegant while the heavy embroidered details give it a rock and roll kick. The shirt is then finished off with the classic western designs of the double front pockets with flaps and snaps, snap down placket, and front and back western yoke. Pair with black denim jeans and cowgirl boots for a complete outfit.
Style(s): LJ6311G
Lifestyle: Western
Material: Cotton/Spandex
Color: Green
Print With more than 60 years of heritage, the Wrangler® Western brand has established itself as the great American jeans lifestyle brand that was born in the spirit of the West and the great outdoors. Starting with the original Wrangler Cowboy Cut® 13MWZ - the jean "made for cowboys by cowboys," and the same jean originally made in 1947 - the brand has become synonymous with the Western way of life. Wrangler Western Wear remains true to the brand's Western roots thriving on the cowboy aesthetic and the preservation of the American legacy while still offering new, style-savvy categories. The brand's latest lines include the Premium Performance Cowboy Cut® jean, an update to the original 13MWZ with added comfort and durability but the same classic style; Rock 47™ by Wrangler®, a contemporary and funky line of Western wear for women; Wrangler® Retro, a line of fresh, cutting-edge Western jeans endorsed by alternative country artist Jason Aldean; Wrangler® National Patriot™, a line of red, white and blue shirts and accessories raising money for wounded or fallen military veterans and their families; and Wrangler® -The Ultimate Riding Jean® offering women fit and function, in and out of the saddle.


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Follow more coverage from the playoffs via Twitter. Follow Evan Mohl on Twitter @EvanMohl for updates on Thursday's Hanks vs. Chapin game and Friday's Andress at Del Valle game.
Follow Felix Chavez on Twitter @FChavezEPTimes for updates from Friday's Franklin vs. San Angelo Central game and Saturday's Americas vs. Abilene Cooper and Montwood vs. Abilene games.
Look for the hashtag #eppreps for Twitter updates on all El Paso high school sports.
All times MST
Class 4A
Div I: Hanks vs. Chapin, 7 p.m. at Irvin's Memorial Stadium.
Andress 30, Del Valle 14 Burges 47, Canutillo 28
Horizon 62, Bowie 18
Wylie 49, Mountain View 21
Fort Worth Nolan 41, Cathedral 8
Franklin 34, San Angelo Central 14
El Dorado 34, Odessa Permian 33
Greenwood 51, Clint 0
Class 5A
Div. II: Americas vs. Abilene Cooper, noon at Odessa's Ratliff Stadium.
Div. II: Montwood vs. Abilene, 5 p.m. at Odessa's Ratliff Stadium.
›› Direct link to chat for mobile


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1. Re: 4G Service - Still Out Across the Nation?philnamy Dec 7, 2011 1:13 PM (in response to diovino82)
I did the same thing yesterday.... I bet they would alleviate thousands of support calls if they had a place you could check first to see if there were outages reported. My electric company does!
2. Re: 4G Service - Still Out Across the Nation?kjowski Dec 7, 2011 2:12 PM (in response to diovino82)
AGREED. I am very frusterated since I jsut got my Xoom and can only use it on WiFi. I am also getting a SIM Card Erro even though I am told my SIM card is fine and activate...WHAT IS GOING ON. why cant they just inform their customers of what is happening so we are not in the dark. I am the point i may just return my Xoom cause what is the point of having it if I cant use it the way I would like.
3. Re: 4G Service - Still Out Across the Nation?OzYbOi Dec 7, 2011 2:29 PM (in response to diovino82)
This is pretty poor on Verizon's part given their lack of communication. If you really want to be customer friendly and not tie up all of your support resources, why not be up front about your outage?
Still no 4g in PDX this AM. Last night the first tech told me (during our 15 min conversation) there were no outages and that my handset was suspect until my issue was escalated and in about 1 min the second tech told me that there were outages. appears they don't even have a way right now to communicate within their own company so frustrations are compounded by misinformation...
4. Re: 4G Service - Still Out Across the Nation?kjowski Dec 7, 2011 2:34 PM (in response to OzYbOi)
That is the general census frusteratin. I still have no 4G or any G on my Xoom at all and have the SIM Card Error. I am going to call them today shortly to see if any more information or help is available. I dont want to keep this if I am going to have these prioblems continue.
5. Re: 4G Service - Still Out Across the Nation?tmg-emedia Dec 7, 2011 2:55 PM (in response to diovino82)
Can you hear me now? Not so much!
Not only have there not been any communications, but what the users are being told makes no sense! Some devices are fine. Others are dead. Does this sound like a "network" problem?
We suspect it is a server/software issue.
Were they hacked? Did they crash and burn? Any user data compromized? Who knows!
The error is one of "authorization." It is reasonable to assume that the services that match the device with the service are down. In the office we have identical RAZRs, half are working, half are dead.
Bottom line is that a communications company has failed misserable in... communications!
They need to come clean now. With the exact problem. Impact. And, anticipated solution and timeline.
6. Re: 4G Service - Still Out Across the Nation?darinb Dec 7, 2011 3:20 PM (in response to tmg-emedia)
Since Last night (Dec 6) around 8 PM my 4G/3G fail after about 30 seconds after a restart or airplane-mode toggle. Is this what you are all experiencing?
I've tried soft and hard resets and so forth with no luck.
7. Re: 4G Service - Still Out Across the Nation?darinb Dec 7, 2011 3:31 PM (in response to darinb)
Also, now I find this:
8. Re: 4G Service - Still Out Across the Nation?MandyB Dec 7, 2011 3:36 PM (in response to darinb)
According to that article, it's only affecting the north eastern coast of the US...
But I'm in Columbia SC and having that exact same issue!
9. Re: 4G Service - Still Out Across the Nation?darinb Dec 7, 2011 3:41 PM (in response to MandyB)
I'm having it in boston which is also not listed as affected.
There is some other chatter over at: http://community.vzw.com/t5/DROID-Charge-by-Samsung/Samsung-Droid-Charge-No-4g-or-3g-network-connection/m-p/744798/highlight/false#M6852
I have 3g working ok-ish with:
Settings -> Wireless & Networks -> Mobile Networks -> System Selection
and switch to CDMA mode


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Watford boss Gianfranco Zola faces no fresh injury concerns ahead of Saturday's trip to Leeds United but Daniel Pudil is suspended.
Fitz Hall looks set to miss out against with a hamstring injury, while Pudil is absent after picking up his fifth caution of the season in Tuesday's draw with Millwall. Geoffrey Mujangi Bia is available and Prince Bauben has also resumed training.
Speaking on Wednesday, Zola said: "With Fitz Hall we are examining him, we don't have the results from today's scan yet but it shouldn't be too bad.
"Geoffrey Mujangi Bia is getting better and better and he's available for selection but we'll see.
"Prince Bauben is back, he started running again today so that is very encouraging but the others – John Eustace, Sergio Neuton and Nyron Nosworthy are not ready yet."
The Hornets travel to Elland Road to complete a busy week in which they've taken four points from two home games against Leicester City and the Lions. The busy schedule is likely to result in changes to the team as Zola looks to utilise his large squad.
Opponents Leeds sit 15th in the Championship table, level on points with the Hornets, and will be looking to bounce back from Tuesday's defeat against Burnley, who are managed by former Watford boss Sean Dyche.
Zola is well aware of the challenge that faces his side and was respectful of Saturday's opponents.
"I played against Leeds in the Premier League; they remain a big team and a big club with a lot of potential," he said. "The club have the possibility to become great because they have a very good foundation."


text:
West Park Villas
In West Park, our luxurious homes offer an uncommon standard of excellence due to their superior design and craftmanship. Live and entertain with pride in West Park!
Quick Delivery Home Available
Plano, TX • Collin County
Community Type: Amenities/Resort
Home Types: Single Family
Priced From: $694,995
Phone: 972-335-9200


text:
SANTA FE, Texas - A driver denied accusations that he pointed a shotgun at a woman who was driving too closely behind him. Instead, he said it was his cane.
Danielle Lane said she was driving home north on FM 646 in Sante Fe on Monday when she came up to a slow-moving vehicle.
She admitted she may have started following the driver too closely, but what happened about a mile later is what got police involved.
"He slammed on his brakes and got out of his car and pointed a shotgun at me," said Lane. "He said, 'I will use this, get off my tail.'"
Lane said when the man turned at the next intersection, she followed and called 911.
Dan Williams, 66, was the man in the other car. He said that's not how it went down at all.
"I didn't pull no weapons," said Williams.
Williams said he doesn't like to drive fast these days. He said he was heading home when the woman pulled up behind him and started honking her horn for about a mile. Out of frustration, he said he stopped at a light and pulled out a cane, not a gun.
"I don't have a shotgun in the car," said Williams. "That was it. When it came out, it maybe looked like a weapon. I don't know."
When police arrived, they found the cane, but they said they also found a long rifle and two black powder pistols. It was enough to take Williams into custody and charge him with a felony.
Copyright 2012 by Click2Houston.com. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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A mysterious "gun" drama left Bricket Wood residents terrified in their homes this week - fortunately Jack Bauer was there to save the day.
People living in Bricket Wood and Garston were shocked out their beds by what sounded like a burst of "gunshot type noises".
Loud explosions could be heard for about an hour and a half through the early hours of Monday morning.
Shortly before 3.30am, one resident reported: "Living near Bricket Wood area close to Garston.
"Hearing loud explosive/gunshot type noises for an hour and a half.
"Very scared/nervous at what these may be?"
On Twitter, John Madden said: "Automatic gunfire Bricket Wood area St Albans. Any ideas what's going on?"
Another resident called the police.
Officers raced to the source of the shots at the Building Research Establishment, on Bucknalls Lane, but found the shooters armed with film cameras rather than guns.
Sarah Spence, spokeswoman for Hertfordshire Constabulary, said they had not been informed filming would be taking place on the night in question.
She said: "We were called at around 2am to reports of gun fire being heard in the Bricket Wood area.
"Officers were in attendance. However, there was no incident.
"It was confirmed some sort of filming was taking place. Normally, we would be contacted to say filming would be happening in the area."
The noises reportedly continued until 4am.
20th Century Fox Television UK was filming the TV drama series 24.
The scenes shot that morning involved a staged car crash and a few of the main characters having a gun battle on the street with the Building Research Establishment.
However, some savvy Jack Bauer fans marched out to the set to see if they could catch sight of their hero in action.
Helen Wilcock tweeted from the set gate: "We have found the 24 set in Bricket Wood and are hoping to see Jack in action!"
Some residents had received letters from the production company warning them of the night shoot.
The 24 team has been filming scenes across London and in Southampton for the new 24: Live Another Day. The current series of the popular drama is showing on Sky 1.


text:
Royal Basmati Rice - 20 lbs.
by Royal | Item #: 369320 | Model #: . |
Top Rated
Non-members pay 10% surchargeJoin now!
- Free Pickup
Delivery estimates, taxes, and fees are based on ZIP Code. Club Pickup orders are based on your club's current price and item availability on the day of payment.
About this itemPremium aged rice grown in the fertile soil of Himalayas Foothills.
Grown in the fertile soil of Himalayas Foothills and nourished by the pure water from the highest snow-covored peaks in the world.


text:
MENIFEE, Calif. (AP) — Authorities searching for a missing 11-year-old autistic boy cordoned off his Southern California home, but volunteers on Wednesday planned to search miles of surrounding desert in hopes of finding him alive.
TV news reports early Wednesday showed yellow crime scene tape around the semirural home of Terry Dewayne Smith Jr. in Menifee.
The Riverside County Sheriff's Department has not said whether foul play was suspected in his weekend disappearance. Calls to department representatives seeking comment were not immediately returned.
The boy was last seen at the home on Saturday and authorities were concerned that he wandered away without food, water or his medication. Searchers have scoured a 55-square mile area where temperatures have topped 100 degrees every day since Terry disappeared.
The number of volunteers and emergency workers combing the dry brown hills of Menifee rose to about 1,000 on Tuesday, but they found no sign of the boy.
"We pledge that we will continue this search effort until such time as circumstances dictate otherwise," Menifee Mayor Scott Mann said at a news conference. "We will continue searching. We will find Terry."
The Sheriff's Department and numerous other agencies, including the FBI, aided in the investigation and search of the region about 70 miles southeast of Los Angeles with the help of bloodhounds, helicopters and horseback riders.
The 4-foot-8 boy with sandy brown hair and brown eyes was last seen wearing blue basketball shorts. Local children were asked to not wear blue, to help avoid confusion.
Terry was last seen when he followed his 16-year-old half-brother, who told the boy to go home, the Desert Sun reported. The boy's mother didn't realize he was missing until the next day.
Terry's mother shared details of the boy's habits on a Facebook page where the volunteer search was being organized. Without his medication, Terry may be "over sensitive and may be walking on his tiptoes," the page said.
Searchers were also instructed to call him by his nickname "Juju" because hearing his full name called out might cause him to believe he's in trouble and flee.
Terry's aunt, Tracy Armato, told KCAL-TV that searchers should "be gentle. We don't know if he'll be scared of all the searchers."


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By Bob Sherwood
It feels like the calm before the storm at the Excel Centre today. The area is thronged with yellow-jacketed police and community support officers who are clearly on heightened alert but with hardly anyone to marshal. The FT's photographer was stopped and searched twice by Met officers this morning as we garnered opinions about the G20 among the local community. At one point he was surrounded by five bicycle officers who wanted to see the images on his camera. Our credentials were checked over the police radio.
The front of the Excel Centre is already coned off and some roads are closed. Police vans and trucks, including the underwater and confined space search unit, are on pretty much every surrounding road. No protesters have arrived in the area yet, though.
Most locals seem bemused by the attention and are fearful of the disruption. They don't quite know what to expect over the next couple of days, but most are not looking forward to it. Apart from Ayoub Mzee, who is walking around Custom House high street in a Barack Obama inauguration cap.
"The big chief is coming to my town," he says excitedly.
Bob Sherwood is the FT's London and south-east correspondent


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Romance Was Born x Samuel Hodge AW13 Lookbook
Fashion fairytale.
Samuel Hodge, who shot July Beauty Daily last year and 'Hated and Proud' for our 100th issue, has done an amazing job on Romance Was Born's latest lookbook. Taking an antique store and what we assume to be a magical forest as its setting, the collection's inspirations are brought to life in the whimsical images.
There's a very regal feel to AW13 with ruffled yokes and sweetheart collars which take cues from the flamboyant Fauntleroy suit made popular by Frances Hodgson Burnett's 1885 children's book Little Lord Fauntleroy. The three-tiered, costume-cool corset gown (already worn by Nicki Minaj) is truly fit for a queen.
After curating the Johnston Collection, designers Anna Plunkett and Luke Sales were inspired by pieces from the museum and have worked Chinaware florals into the collection, as well as a print inspired by Saffordshire porcelain figurines.
Sydney-based artist Phil James created the collection's hero print — a modern take on Thomas Gainsborough's 'The Blue Boy' painting — which appears on a signature, long-sleeve dress.


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Rodarte Pitti Immagine Collection
Ethereal gowns and abandoned factories.
Eighty-eight brands were selected to present at the prestigious Pitti. Amongst them, Rodarte was a stand out. With a helping hand from Alexandre de Betak and Bureau Betak, sisters Kate and Laura Mulleavy used neon tubing and old, cracked mirrors to transform an abandoned factory building in central Florence into a customised space. They suspended ten floor-length gowns from the ceiling, each one carefully constructed from feathers, Swarovski crystals, silk georgette, chiffon, organza, satin, taffeta, lame, sequins, and tulle. Four of the gowns even incorporated hand-forged gold metal pieces in breastplates, belts and metal headbands. The colour palette included pink, melon, gold, white, aqua, pistachio, dusty blue, lapis lazuli, lavender, mauve and crimson.
The hanging dresses recalled classical sculptures. Unsurprisingly, the sisters were inspired by Florentian art history and religious iconography, specifically Fra Angelico's frescoes in the monks' cells at the Convent of San Marco and Bernini's The Ecstasy of Saint Teresa. If you weren't one of the lucky few invited to preview their work, you can see the collection at the Los Angeles County Museum of Art, where the pieces will live on after Pitti.


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With the final releases of Flash Player 10.1 and AIR 2, you are invited to a series of free webinars introducing the new multi-screen development capabilities of the Flash Platform. You will discover the exciting new features of Flash Player 10.1 and AIR 2 and learn the best practices from leading industry experts on how to create and optimize web content, video, and applications across desktop and mobile. To register, visit http://www.adobe.com/go/multiscreen
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Felony pollution charges dropped against Abbotsford inventor
Six felony charges were dismissed Monday in U.S. district court in Texas against an Abbotsford man who was accused of environmental offences related to a battery recycling plant.
In exchange, inventor Herb Larsen signed a plea agreement and received one year of unsupervised probation for the misdemeanour offence of "negligent release of a hazardous air pollutant."
Larsen's lawyer, Dick DeGuerin of Texas, likened the dismissal of the felony charges to someone who has been charged with murder being found guilty of "spitting on the sidewalk."
He said the plea agreement, which was brought to him by federal prosecutors involved in the case, amounted to an admission by the State that it did not have a case against Larsen and his co-accused.
"It was a way for the EPA (Environmental Protection Agency) to save face after they spent so much money prosecuting this case," he said.
Larsen said he was reluctant to sign the plea agreement and had wanted the case to go to trial.
But as part of the agreement, felony charges were dropped against his three co-accused, and he avoided hundreds of thousands of dollars in potential additional legal fees.
"It was one of the most difficult things (signing the plea agreement). I still waffle over it … My reputation is worth more than anything, but I'm tapped out. I can't keep fighting forever," he said.
Larsen, 57, was arrested on a warrant in May 2010 at the Sumas, Wash. border crossing while returning from a guest-speaker stint at a Christian men's retreat in California.
He was charged with six felony offences, including conspiracy to store and dispose of hazardous waste and storing hazardous waste without a permit, for his involvement with Battery Reclamation Inc. (BRI) in Pecos, Texas.
Larsen, an industrial design engineer, said he became involved with then eight-year-old operation – known as Battery Conservation Technology Inc. – after he was approached to design and develop environmental technology for the plant in 2000.
Several months later, the company was unable to raise the funds to continue with research and development. Larsen said he rounded up $1.8 million in investments, and a new company, BRI, was formed.
He said it took over two years for the Texas Commission of Environmental Quality (TCEQ) to transfer the hazardous waste permit so that the company could continue operating.
Larsen said the former owners had left the property in a mess, and the new owners agreed to clean up one-sixth of the mess each year. He said they met that goal in the first year, spending more than $1 million to do so.
Once the TCEQ approved the environmental permits, the plant went into operation for four months before the permit came up for renewal, and the entire process began again. Larsen said it was "impossible to please" the agency, which "dragged its feet at every juncture in the process."
Larsen said the cost of hiring lawyers and consultants depleted the investment funds and, with the plant unable to operate and generate revenue, the owners "walked away" from the operation, resulting in the felony charges being laid.
The misdemeanour to which Larsen pleaded guilty involved canvas sacks degrading and spilling zinc manganese powder on the ground, causing a "substantial risk of fire or explosion," according to court documents.
Larsen said the charges and the court case have been devastating to him.
"It all seems so senseless that after years of providing world-class industrial solutions to environmental problems … that I was so maliciously pursued as an environmental terrorist," he said.


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WikiPad Gaming Tablet Coming This Spring For $249by Jason Inofuentes on 2/7/2013 9:07 PM EST
- Posted in
- Android
- Mobile
- Tegra 3
- Tablets
- Android 4.1
- jelly bean
- WikiPad
11 Comments
Back to Article
thesavvymage - Friday, February 08, 2013 - linkInstead of making the tablet and housing, why not just make the housing fit a Nexus 7? Many people already own one, and anyone who does is NOT going to make this as a second purchase. I think they would sell a ton of controller housings if it were for the N7. Only advantage i see is the microsd slot Reply
Visual - Friday, February 08, 2013 - link^ what he said.
Also, "Purpose built consoles and handhelds have been rolling out"... really? Cos I still can not buy neither a nVidia SHIELD nor a Razer Edge/Fiona anywhere...
And where I live, not even the Archos GamePad is being sold. Not that I would pay money for it, just saying. Reply
nbgambler - Monday, February 11, 2013 - linkHe may have been referring to PS3, 360, PSP, etc.... Reply
daniel_p - Friday, February 08, 2013 - linkI don't know why, but i see this devices as a tough sell... i agree with guy who posted before, making the housing will be a better idea Reply
brandonicus - Friday, February 08, 2013 - linkMaybe I am missing something, but where are all of these excellent games? Sure there are a few fun games on android, but most of them aren't even made for these kinds of controls. I can see NV's Shield idea of streaming games being a cool idea...but this...I don't know, maybe someone can point out some good games for me (besides emulators [which maybe that is what people will use this for?]) Reply
hfm - Friday, February 08, 2013 - linkWhy are they calling this "Wiki" pad... Wiki already has a totally different connotation, this has got to be the worst named product outside of some of Samsung's phones.. Reply
cfaalm - Sunday, February 10, 2013 - linkI'm actually saving my money for the wiki leaks. gaming pad Reply
bdawg05 - Monday, February 11, 2013 - linkThis is the way of the future. With the exception of *cloud computing, MMO games have latency. That latency means you need a dedicated video card and that's about to become a reality with these devices. Add in Occulus Rift VR goggles. With this technology, you'll be able to be in a doctor's office, airport, or in the backseat of a car and fully immersed within the world which you hold in your hands. THAT is a powerful statement to make. I am already signed up for testing/development coding with the test kit that comes my way in April. The commercial version is still a ways out (no commercial release date yet), but when it comes to be, gaming tablets plus VR just got real. Encourage you to go check out Occulus Rift VR goggles and the future they present dedicated gamers.
*As mentioned in the beginning, Cloud Computing brings many people single player games and maybe even coop, but nothing player vs player or MMO that regards fast speeds from dedicated processors/video processes with dedicated video ram and slow latency. Reply
firestarter - Thursday, June 06, 2013 - linkI agree completely Occulus Rift if it married this bad boy we would be nearer the grail -- I never wanted play games on my mums TV! Reply
firestarter - Thursday, June 06, 2013 - linkI think stream from your PC to this Tablet use the HDMI out link it to the Occulus Rift heh presto thats very very cool bdawg05 I am with your wavelength Reply
firestarter - Thursday, June 06, 2013 - linkThe spec war and pricing the new kid on the block wins hands down - on the wikipad website it also has HDMI out and a mike and 2 MG pixal camera as opposed to 0.3 -- umm this is a real contender -- not sure about the name but heck Google Nexus who would have thought!
Max Payne with controller support I like that itching to play that on the go without my fingers annoying me.... Reply


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Watch these videos to learn how to use PowerPoint 2013. Get started with the new version to see how to do everyday tasks.
Inside this course:
Start using PowerPoint (2:05)
The best way to learn about PowerPoint 2013 is to start using it.
Save a PowerPoint presentation (1:49)
In this video, learn how to save your presentation to prevent losing all of your hard work, and find out how to print your presentation.
Insert items in a presentation (2:37)
This video shows you how to make your presentation more visually interesting by inserting things like pictures, headers, footers, shapes, and more.
Finalize and review a presentation (2:02)
See how to add some design elements, such as themes and transparencies, and review your presentation before presenting it to your audience.
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Watch this video for some tips on how to deliver your presentation, including how to deliver on two monitors using Presenter view.
Course summary
A brief reminder of the key points in this course.
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PLANS have gone on display for a multi-million pound development to revamp a once-stricken leisure centre.
Highworth Recreation Centre was close to shutting its doors for good after struggling with debt, but Swindon Council decided to write off the sum of up to £610,000.
A consultation started this week as the town seeks its share of a nearly £500m Sport England investment in grassroot sport over the next four years.
Residents will have their say in a public consultation, which runs until March 11, on the plans which includes a floodlit artificial grass pitch at the centre, a new cricket pitch, an informal running track and more parking.
There will also be the opportunity to comment on a proposal for an artificial grass pitch on the Warneford School site.
Chairman of Highworth Sporting Hub, Geoff Halls said: "This really is a once-in-a-lifetime opportunity for all sports clubs and people in Highworth.
"The Highworth sports clubs have a vision for sport in Highworth and it has had some positive indications of support from funders including Sport England and the Football Foundation.
"However, in order to proceed the vision must have general community support and that is why we are undertaking this consultation."
All households will receive a questionnaire to complete and return by Freepost. There will also be two public drop-in sessions when questions can be asked at the Highworth Community Centre on Tuesday and the Highworth Town Council Community Rooms on Saturday, March 2.
The results of the consultation will be made public and presented to Swindon Council and Highworth Town Council.


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Taylor Swift clearly touched a nerve at Spotify last week when she pulled all of her music from the streaming service.
Daniel Ek, Spotify's chief executive, has responded to her move by publishing a 1,800 word essay that defends the company's business model and reveals some fascinating numbers about its growth. Read more


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At ScarfWorld.com we pride ourselves on high-quality, stylish scarves and impeccable customer service on and offline. Our experienced team is ready to answer any questions you may have. We also have an extensive Scarf Information Section with all you need to know about wearing and caring for your favourite scarves.
"Thank you for the above delivery which arrived today, and also for the prompt and obliging way in which the young woman on your customer services dealt with the confusion regarding this order." - N. Stonier


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HOUSTON - Several men have been accused of trying to buy stolen merchandise.
Local 2 investigates has learned an undercover sting operation by the Houston Police Department and the Bureau of Alcohol, Tobacco, and Firearms, has netted three arrests.
A Harris County prosecutor said in court that the men were trying to buy $167,000 worth of jewelry stolen in recent smash-and-grab-style robberies across the Houston area.
Nearly 20 pawn shops and jewelry stores have been targeted in the Houston area since December.
All three of the men recently arrested have the same last name, but their relationship is unclear.
Esequiel Mosqueda, 37, and Hugo Mosqueda, 33, have been charged with organized criminal activity, along with Julio Mosqueda, whose age has not been released.
According to the prosecution, each of the three men agreed to purchase merchandise supposedly stolen in the rash of smash-and-grab crimes earlier this year, including 70 gold rings.
The men were jailed but have since been released on $20,000 bond each. They are due back in court June 19.
If you have a news tip or question for KPRC Local 2 Investigates, drop them an e-mail or call their tipline at (713) 223-TIPS (8477). Copyright 2012 by Click2Houston.com. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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PR's Cabrera helps bid for bigs during Classic
SAN FRANCISCO -- When Fernando Cabrera nailed down the final two outs of Puerto Rico's semifinal victory over Japan on Sunday night, it was his third save of the Classic in four appearances.
A 6-foot-4 right-hander with seven years of Major League experience with the Indians, Orioles and Red Sox, Cabrera has retired six of the seven hitters he has faced, walking one with three strikeouts. He is hoping to use his work in the Classic to open some eyes with the Angels' brass in his bid to claim a job in their bullpen -- if not immediately, sometime this season.
Cabrera is 8-7 with a 5.24 ERA in 132 Major League appearances. He hasn't pitched in the Majors since making one appearance for the Red Sox in 2010. He spent last season with the Mets' Triple-A Buffalo affiliate in the International League, making 57 appearances.
"My focus now is helping my team win this for our country," Cabrera, 31, said. ""Everything's working, everyone is doing their job. That's how winners are. We have superstars, guys like [Yadier] Molina, [Carlos] Beltran, [Alex] Rios and [Angel] Pagan, and we also have these young guys who are learning how to win. Everybody's contributing. If we aren't hitting, we're playing good defense and pitching well. We've been building confidence as we've gone along.
"Hopefully, what I've been doing in this tournament can help me the rest of the year. My goal is to get back to the big leagues. I want to have another chance. Everything starts in Spring Training, and that means the WBC for me. The Angels gave me an opportunity, and I'm going to give them everything I've got. Right now, I'm helping this Puerto Rico team try to win the tournament."
Lyle Spencer is a reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.


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Global oil prices slipped on Wednesday, with losses in U.S. crude widening the trans-Atlantic spread for a second day, amid signs that Libyan exports might resume and indications that oil was flowing into the depleted Cushing storage hub.
The spread between Brent and West Texas Intermediate (WTI), the U.S. benchmark delivered at Cushing, Oklahoma, reached more than $6 a barrel, the widest since June. It has expanded by more than $3 since Tuesday, the biggest two-day move since early February, as traders bet that tightening Midwest supply conditions were easing.
Government data on Wednesday showed Cushing oil inventories were the lowest since March 2012, a 25 percent drop in seven weeks. But traders instead focused on news that an oil-by-rail pipeline was pumping oil back into local storage tanks for the first time in a year.
Industry intelligence group Genscape reported that the 90,000 barrel-per-day Hawthorn pipeline, which carries oil from a terminal in Stroud, Oklahoma, to Cushing, was preparing to restart for the first time since August 2012.
Brent futures for October fell 38 cents at $109.77 a barrel by 2:03 p.m. EDT (1803) GMT. U.S. October oil fell $1.30 to $103.81 a barrel, off a session low $103.54.
Losses briefly deepened after the minutes of the Federal Reserve's late July meeting showed that it was considering new measures to drain cash from the banking system when it decides to shift away from its current ultra-loose monetary policy.
The Brent/WTI spread also vacillated on Tuesday, when Genscape reported that the Seaway pipeline that carries crude oil from Cushing to the Texas coast had shut. Operator Enterprise Products Partners L.P. said the line was "operating normally" by Wednesday morning.
About half of Libya's more than 1.2 million barrels per day (bpd) of crude oil export capacity is out of action due to strikes and civil unrest, but officials said Tuesday some ports have reopened and more shipments could restart within days.
"The Libyan curtailment is still a wildcard," said Gene McGillian, an analyst with Tradition Energy in Stamford, Connecticut. "The market is taking a wait and see approach to see if exports actually resume."
The situation in Libya is volatile with conflicting reports of port activity and varying estimates of oil exports.
The head of Libya's Petroleum Facilities Guard said on Tuesday striking workers at a key oil port fired on civilians and injured at least one person. Independent confirmation of the shooting was not immediately available.
The political crisis in Egypt also stoked supply worries.
Egypt is home to the Suez Canal and the Sumed pipeline, which together carry around 4.5 million bpd of oil between the Red Sea and the Mediterranean. The Egyptian army has said it will guarantee the safety of the canal and pipeline but any disruption could have a major impact on oil prices. (Additional reporting by Jeanine Prezioso in New York, Peg Mackey and Christopher Johnson in London, Luke Pachymuthu in Singapore; Editing by Jonathan Leff)


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Looking for more information about Faiga Grynbaum?
Search through millions of records to find out more.
Search through millions of records to find out more.
1913 — Starachowice, Poland
Faiga was one of nine children born to religious Jewish parents in Starachowice, a town in east-central Poland. Their small one-story house served as both the family's residence and their tailor shop. Faiga worked in the shop sewing women's clothes; the tailoring was often done in exchange for goods such as firewood or a sack of potatoes.
1933-39: In 1935 Faiga married Haskel Ochervitch. She moved to Kielce, a larger town some 25 miles southwest of Starachowice, where her husband worked selling meat to the Polish army. The couple had one daughter before Haskel emigrated to America in the late 1930s. He purchased a shoe factory in New York City. When he sent for Faiga and his daughter to join him, World War II had already erupted, making emigration impossible. Faiga had to remain in Poland.
Europe 1933, Poland indicated
See maps
1940-45: Faiga and her daughter returned to Starachowice and lived with Faiga's family under the German occupation. In October 1942 SS guards forced the town's Jews into the marketplace. Faiga, who was already a forced laborer at a nearby factory, was lined up with the "able-bodied" workers. Her mother and daughter were selected for deportation together with others who were young or elderly. Faiga was marched with others to a nearby forced-labor camp, where prisoners made German uniforms.
In mid-1943 Faiga was shot and killed during a mass escape attempt from the camp. Her mother and daughter perished at the Treblinka extermination camp.
Rozia was the second-oldest of nine children born to religious Jewish ...
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HOUSTON - Police are searching for the person who shot and killed a man in his southwest Houston home overnight.
Houston police said they received a call around 5:30 a.m. Saturday about a shooting in the 15000 block of Ironside Hill Drive. Inside the home, they found 53-year-old Marty Franklin dead from multiple gunshot wounds, detectives said.
"Patrol officers were dispatched to a home invasion that had just occurred," Sgt. Eli Cisneros said. "When the officers arrived, they discovered the homeowner had been shot multiple times."
According to HPD, the two masked gunmen went there to rob Franklin.
"The preliminary investigation at this point suggests robbery was the apparent motive," said Cisneros.
Franklin's brother, Michael Dale, got the call soon after police identified the body.
"It's just one of them things that you never expect, you know, to get a call saying that, 'Hey come by a house. One of your family members is dead,'" Dale said.
Franklin has a daughter in her 20's who doesn't live with him. Police said nobody else was injured.
Anyone with information about the killing is asked to call the HPD Homicide Division at 713-308-3600 or Crime Stoppers at 713-222-TIPS.
Copyright 2012 by Click2Houston.com. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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Hey there, time traveller!
This article was published 18/12/2012 (1708 days ago), so information in it may no longer be current.
One of the best jokes about Winnipeg -- and hardly the most unfair -- was this city was planned during 10 crazy days in 1905.
Back in the midst of the railway boom, streets were carved out of the prairie and buildings went up at a rate determined only by the financial limitations of the city's early entrepreneurs. There wasn't anything resembling modern urban planning, a process by which a proposed use for a piece of land is considered within the context of what already surrounds it -- and what might surround it in the future.
What we had, instead, was a development binge that resulted in modern hangovers such as the CPR Winnipeg Yards splitting downtown from the North End and heavy industry abutting residential streets in St. Boniface. A century after the boom ended, Winnipeg is still trying to contend with an odd jumble of overlapping land uses approved at a time when only Chicago was growing faster among North American cities.
While the steam escaped from the railway boom almost a century ago, this city never actually stopped growing. It just grew more slowly than other major Canadian centres and is now virtually tied with Hamilton as the eighth and ninth largest metropolitan areas in Canada.
The Winnipeg metro area is now estimated at 773,000 people, with 700,000 residing within the city itself, according to Statistics Canada. And more people are expected soon.
In fact, our modest but resurgent growth forced city planners to come up with a new land-use blueprint a few years back -- Our Winnipeg, whose goal is nothing less ambitious than to map out how the city will house and employ an additional 180,000 people over the next couple of decades.
Much of this document involves general land-use principles planners are supposed to consider when they make development decisions. But there are actual maps marking out future areas where the likes of new roads, industrial areas and residential homes are supposed to go.
On page 75 of an Our Winnipeg handbook called Complete Communities, you'll find a map of 15 "precincts" set aside for purely residential purposes. One of those areas, Precinct H, sits at the northeast corner of Transcona.
Over the past few years, the primary land owner of Precinct H, a developer called North Grassie Properties, has been trying to put together a plan to actually build some homes on this land. Frustrated by delays, the developer's agent complained in November the city was holding it back by demanding additional consultation with its neighbours.
As Transcona Coun. Russ Wyatt explained, some of those neighbours include heavy industrial operations, both inside city limits and in the neighbouring RM of Springfield, all of whom fear their activities could be curtailed. So in one of his last acts as a member of council's property committee, Wyatt instructed the city to come up with a new Precinct H planning process that would take the concerns of industrial operators into account. One of those businesses is Border Chemical, a sulfuric acid manufacturer that occupies a sprawling complex on the north side of Gunn Road. In an interview earlier this month, general manager Dennis Smerchanski said he's concerned about plans for homes and a schoolyard a few hundred metres away from an access road for sulfuric acid trucks.
He said North Grassie is mistaken in its belief heavy industry on the edge of Transcona supports the idea of nearby residential development. But more importantly, he said nobody from the city -- neither a planner, nor any other official -- asked Border Chemical's opinion about earmarking the neighbouring land for new homes.
"After being here for 53 years, we'd like to see a process where we have input into decisions," Smerchanski said.
In other words, the city's new land-use guide, intended to map out future growth in such a way that minimizes land-use conflicts, proposed a new residential area within sight of a sulfuric acid factory. Consultations were only done with the majority owner of Precinct H -- not the neighbouring land owners.
To be fair to the city, no development on Precinct H can proceed until everyone is happy. The time it will take to consult all the players is what upset North Grassie Properties in the first place.
But it doesn't inspire much confidence in the city's future growth when one out of 15 areas earmarked for new single-family homes is already the subject of a land-use conflict.
Already faced with a rental-apartment crisis, Winnipeg is running out of land for new homes. It will take more than colour-coded maps and promises of consultation to solve this problem before the absence of housing severely curtails Winnipeg's growth.


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Originally written on Larry Brown Sports | Last updated 10/11/14
Lindsey Vonn and Tiger Woods appear to be enjoying their relationship and doing a great job of ignoring what gossip magazines and tabloids are saying about them. That does not mean they will ever get past the dating phase. During a recent interview with Vogue magazine, Vonn talked about how she made a mistake by [...]
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Submit News
Researchers Propose New Way to Explain How Life Began on Earth
Jason Mick
December 13, 2012 5:19 PM
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By looking at information stored in chemistry, says former NASA fellow, life from non-life can be explained
An outstanding question in the
field of evolutionary biology
and biochemistry is how the complex, fragile biochemicals that made up life
arose and transformed biomaterial
in the early Earth from non-living to the earliest "living" organisms. Some researchers have looked for quasi-alive constructs
like prions or viruses
for clues.
But a new paper by Paul Davies, an
Arizona State University
Regents' Professor and director of the Beyond Center for Fundamental Concepts in Science, and Sara Walker, a NASA post-doctoral fellow at the Beyond Center,
in the journal
suggests that researchers are approaching the problem in the wrong way.
They suggest that rather looking at the "hardware" (biochemicals), they look at the "software" (chemically encoding information). The authors suggest that the defining line between the living and non-living is the ability to manage encoded information, thus the key question is how this information handling arose.
Could the clue to how life arose lie in how it encodes information?
Comments Prof. Walker, "When we describe biological processes we typically use informational narratives -- cells send out signals, developmental programs are run, coded instructions are read, genomic data are transmitted between generations and so forth. So identifying life's origin in the way information is processed and managed can open up new avenues for research."
"Chemical based approaches have stalled at a very early stage of chemical complexity -- very far from anything we would consider 'alive.' More seriously they suffer from conceptual shortcomings in that they fail to distinguish between chemistry and biology."
"We propose that the transition from non-life to life is unique and definable," Prof. Davies adds, "We suggest that life may be characterized by its distinctive and active use of information, thus providing a roadmap to identify rigorous criteria for the emergence of life. This is in sharp contrast to a century of thought in which the transition to life has been cast as a problem of chemistry, with the goal of identifying a plausible reaction pathway from chemical mixtures to a living entity."
"To a physicist or chemist life seems like 'magic matter. It behaves in extraordinary ways that are unmatched in any other complex physical or chemical system. Such lifelike properties include autonomy, adaptability and goal-oriented behavior -- the ability to harness chemical reactions to enact a pre-programmed agenda, rather than being a slave to those reactions."
"We believe the transition in the informational architecture of chemical networks is akin to a phase transition in physics, and we place special emphasis on the top-down information flow in which the system as a whole gains causal purchase over its components. This approach will reveal how the logical organization of biological replicators differs crucially from trivial replication associated with crystals (non-life). By addressing the causal role of information directly, many of the baffling qualities of life are explained."
Crystals are also self-replicating, but they lack the flexibility of life.
[Image Source: Giovanni Dall'Orto]
If that all sounds a bit abstract, it is.
But basically it seems that the pair are arguing that by looking at differences between the self-replicating information in biochemicals (e.g. RNA) verus self-replication information in inorganic/non-living constructs (e.g. crystals), researchers may be able to retrace the process of how life arose on Earth more easily than if they merely focus on painstakingly mixing chemical constituents, hoping something arises.
Interface [via Arvix]
Arizona State Univ.
"We are going to continue to work with them to make sure they understand the reality of the Internet. A lot of these people don't have Ph.Ds, and they don't have a degree in computer science." -- RIM co-CEO Michael Lazaridis
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how the brain wires itself up during development, how the end result can vary in different people and what happens when it goes wrong
Thursday, August 11, 2011
Split brains, autism and schizophrenia
The diagnoses ranged from schizophrenia and bipolar disorder to depression and a range of "minor" psychiatric conditions. It was found that the affected individuals had all inherited a genetic anomaly – a translocation of genetic material between two chromosomes. This basically involves sections of two chromosomes swapping with each other. In the process, each chromosome is broken, before being spliced back to part of the other chromosome. In this case, the breakpoint on chromosome 1 interrupted a gene, subsequently named Disrupted-in-Schizophrenia-1, or DISC1.
That this discovery was made using classical "cytogenetic" techniques (physically looking at the chromosomes down a microscope) and in a single family is somehow pleasing in an age where massive molecular population-based studies are in vogue. (A win for "small" science).
The discovery of the DISC1 translocation clearly showed that disruption of a single gene could lead to psychiatric disorders like schizophrenia. This was a challenge to the idea that these disorders were "polygenic" – caused by the inheritance in each individual of a large number of genetic variants. As more and more mutations in other genes are being found to cause these disorders, the DISC1 situation can no longer be dismissed as an exception – it is the norm.
It also was the first example of a principle that has since been observed for many other genes – namely that the effects of the mutation can manifest quite variably - not as one specific disorder, but as different ones in different people. Indeed, DISC1 has since been implicated in autism as well as adult-onset disorders. It is now clear from this and other evidence that these apparently distinct conditions are best thought of as variable outcomes that arise, in many cases at least, from disturbances of neurodevelopment.
Since the initial discovery, major research efforts of a growing number of labs have been focused on the next obvious questions: what does DISC1 do? And what happens when it is mutated? What happens in the brain that can explain why psychiatric symptoms result?
We now know that DISC1 has many different functions. It is a cytoplasmic protein - localised inside the cell - that interacts with a very large number of other proteins and takes part in diverse cellular functions, including cell migration, outgrowth of nerve fibres, the formation of dendritic spines (sites of synaptic contact between neurons), neuronal proliferation and regulation of biochemical pathways involved in synaptic plasticity. Many of the proteins that DISC1 interacts with have also been implicated in psychiatric disease.
This new study adds another possible function, and a dramatic and unexpected one at that. This function was discovered from an independent angle, by researchers studying how the two hemispheres of the brain get connected – or more specifically, why they sometimes fail to be connected. The cerebral hemispheres are normally connected by millions of axons which cross the midline of the brain in a structure called the corpus callosum (or "tough body" – (don't ask)). Very infrequently, people are born without this structure – the callosal axons fail to cross the midline and the two hemispheres are left without this major route of communication (though there are other routes, such as the anterior commissure).
The frequency of agenesis of the corpus callosum has been estimated at between 1 in 1,000 and 1 in 6,000 live births – thankfully very rare. It is associated with a highly variable spectrum of other symptoms, including developmental delay, autistic symptoms, cognitive disabilities extending into the range of mental retardation, seizures and other neurological signs.
Elliott Sherr and colleagues were studying patients with this condition, which is very obvious on magnetic resonance imaging scans (see Figure). They initially found a mother and two children with callosal agenesis who all carried a deletion on chromosome 1, at position 1q42 – exactly where DISC1 is located. They subsequently identified another patient with a similar deletion, which allowed them to narrow down the region and identify DISC1 as a plausible candidate (among some other genes in the deleted region). Because the functions of proteins can be affected not just by large deletions or translocations but also by less obvious mutations that change a single base of DNA, they also sequenced the DISC1 gene in a cohort of callosal agenesis patients and found a number carrying novel mutations that are very likely to disrupt the function of the gene.
While not rock-solid evidence that it is DISC1 that is responsible, these data certainly point to it as the strongest candidate to explain the callosal defect. This hypothesis is strongly supported by findings from DISC1 mutant mice (carrying a mutation that mimics the effect of the human translocation), which also show defects in formation of the corpus callosum. In addition, the protein is strongly expressed in the axons that make up this structure at the time of its development.
The most obvious test of whether disruption of DISC1 really causes callosal agenesis is to look in the people carrying the initial translocation. Remarkably, it is not known whether the original patients in the Scottish pedigree who carry the DISC1 translocation show this same obvious brain structural phenotype. They have, very surprisingly, never been scanned.
This new paper raises the obvious hypothesis that the failure to connect the two hemispheres results in the psychiatric or cognitive symptoms, which variously include reduced intellectual ability, autism and schizophrenia. This seems like too simplistic an interpretation, however. All we have now is a correlation. First, the implication of DISC1 in the acallosal phenotype is not yet definitive – this must be nailed down and replicated. But even if it is shown that disruption of DISC1 causes both callosal agenesis and schizophrenia (or other psychiatric disorders or symptoms), this does not prove a causal link. DISC1 has many other functions and is expressed in many different brain areas (ubiquitously in fact). Any, or indeed, all of these functions may in fact be the cause of psychopathology.
One prediction, if it were true that the lack of connections between the two hemispheres is causal, is that we would expect the majority of patients with callosal agenesis to have these kinds of psychiatric symptoms. In fact, the rates are indeed very high – in different studies it has been estimated that up to 40% of callosal agenesis patients have an autism diagnosis, while about 8% have the symptoms of schizophrenia or bipolar disorder. (Of course, these patients may have other, less obvious brain defects as well, so even this is not definitive).
Conversely, we might naively expect a high rate of callosal agenesis in patients with autism or schizophrenia. However, we know these disorders are extremely heterogeneous and so it is much more likely that this phenotype might be apparent in only a specific (possibly very small) subset of patients. This may indeed be the case – callosal agenesis has been observed in about 3 out of 200 schizophrenia patients (a vastly higher rate than in the general population). Another study, just published, has found that mutations in a different gene – ARID1B – are also associated with callosal agenesis, mental retardation and autism. More generally, there may be subtle reductions in callosal connectivity in many schizophrenia or autism patients (including some autistic savants).
Whether this defect can explain particular symptoms is not yet clear. For the moment, the new study provides yet another possible function of DISC1, and highlights an anatomical phenotype that is apparently present in a subset of autism and schizophrenia cases and that can arise due to mutation in many different genes (of which DISC1 and ARID1B are only two of many known examples).
One final note: formation of the corpus callosum is a dramatic example of a process that is susceptible to developmental variation. What I mean is this: when patients inherit a mutation that results in callosal agenesis, this phenotype occurs in some patients but not all. This is true even in genetically identical people, like monozygotic twins or triplets (or in lines of genetically identical mice). Though the corpus callosum contains millions of nerve fibres, the initial events that establish it involve very small numbers of cells. These cells, which are located at the medial edge of each cerebral hemisphere, must contact each other to enable the fusion of the two hemispheres, forming a tiny bridge through which the first callosal fibres can cross. Once these are across, the rest seem able to follow easily. Because this event involves very few cells at a specific time in development, it is susceptible to random "noise" – fluctuations in the precise amounts of various proteins in the cells, for example. These are not caused by external forces – the noise is inherent in the system. The result is that, in some people carrying such a mutation the corpus callosum will not form at all, while in others it forms apparently completely normally (see figure of triplets, one on left with normal corpus callosum, the other two with it absent). So, an all-or-none effect can arise, without any external factors involved.
This same kind of intrinsic developmental variation may also explain or at least contribute to the variability in phenotypic outcome at the level of psychiatric symptoms when these kinds of neurodevelopmental mutations are inherited. Even monozygotic twins are often discordant for psychiatric diagnoses (concordance for schizophrenia is about 50%, for example). This is often assumed to be due to non-genetic and therefore "environmental" or experiential factors. If these disorders really arise from differences in brain wiring, which we know are susceptible to developmental variation, then differences in the eventual phenotype could actually be completely intrinsic and innate.
Osbun N, Li J, O'Driscoll MC, Strominger Z, Wakahiro M, Rider E, Bukshpun P, Boland E, Spurrell CH, Schackwitz W, Pennacchio LA, Dobyns WB, Black GC, & Sherr EH (2011). Genetic and functional analyses identify DISC1 as a novel callosal agenesis candidate gene. American journal of medical genetics. Part A, 155 (8), 1865-76 PMID: 21739582
Halgren C, Kjaergaard S, Bak M, Hansen C, El-Schich Z, Anderson CM, Henriksen KF, Hjalgrim H, Kirchhoff M, Bijlsma EK, Nielsen M, den Hollander NS, Ruivenkamp CA, Isidor B, Le Caignec C, Zannolli R, Mucciolo M, Renieri A, Mari F, Anderlid BM, Andrieux J, Dieux A, Tommerup N, & Bache I (2011). Corpus Callosum Abnormalities, Mental Retardation, Speech Impairment, and Autism in Patients with Haploinsufficiency of ARID1B. Clinical genetics PMID: 21801163
9 comments:
Thanks a lot for this review!ReplyDelete
It is surprising though that the absence of the corpus callosum, which is a super-large structure in our brains is only causing very mild phenotypes, at least in mice. Even in humans, some people seems to be doing fine without it.
The Corpus Callosum being a recent innovation, present only in eutherian mammals, I was wondering if the phenotypical disparities you are describing could be explained by the fact that this structure didn't had the time to evolve a truly original and vital function, and is still redondant with the other major commissures of the forebrain?
An interesting, and related, point:ReplyDelete
It appears that the corpus callosum appeared in evolving mammals at the same time (or perhaps shortly after) as a major miRNA cluster; at least both appear to be present in all eutherian ("placental") mammals and absent in all other vertebrates:
"In this study, we describe a detailed analysis of the miRNA cluster (hereafter mir-379/mir-656 cluster) located within the imprinted DLK-DIO3 region on human chromosome 14. We show that orthologous miRNA clusters are present in all sequenced genomes of the placental (eutherian) mammals but not in the marsupial (metatherian), monotreme (prototherian), or any other vertebrate genomes. We provide evidence that the locus encompassing this cluster emerged in an early eutherian ancestor prior to the radiation of modern placental mammals by tandem duplication of the ancient precursor sequence. The original amplified cluster may have contained in excess of 250 miRNA precursor sequences, most of which now appear to be inactive. Examination of the eutherian genomes showed that the cluster has been maintained in evolution for approximately 100 Myr.
Analysis of genes that contain predicted evolutionarily conserved targets for miRNAs from this cluster revealed significant overrepresentation of the Gene Ontology terms associated with biological processes such as neurogenesis, embryonic development, transcriptional regulation, and RNA metabolism. Consistent with these findings, a survey of the miRNA expression data within the cluster demonstrates a strong bias toward brain and placenta samples from adult organisms and some embryonic tissues.
Our results suggest thatemergence of the mir-379/mir-656 miRNAclusterwas one of the factors that facilitated evolution of the placental mammals. Overrepresentation of genes involved in regulation of neurogenesis among predicted miRNAs targets indicates an important role of the mir-379/mir-656 cluster in this biological process in the placental mammals."
Glazov, E.A., McWilliam, S., Barris, W.C., Dalrymple, B.P. (2008) Origin, Evolution, and Biological Role of miRNA Cluster in DLK-DIO3 Genomic Region in Placental Mammals Mol. Biol. Evol. 25(5):939–948. 2008 doi:10.1093/molbev/msn045
Just wanted to know how do antipsychotics bridge this gap and help patients with psychosis?ReplyDelete
I really like to know about the forms and ways that the brain uses to work, I am in a experiment in xl pharmacy about the unknown power of the human brain !ReplyDelete
I have noticed that if there is one in a family there is usually the other...ReplyDelete
We are having a discussion on this
In many articles listed with PubMed & The National Institute of Health, it's been proven that the parasite Toxoplasma Gondii are the cause of Bi-Polar & Schizophrenia. Go here for a complete article:ReplyDelete
There is definitely so many people that are suffering with these disorders. So much more research has to be done with these so much. This is causing so many issues with do many people. So dangerous to have. Skunk Removal TorontoReplyDelete
Aerophobia, or fear of flying, may be associated with numerous other phobias. Sometimes it appears on its own. The fear of flying is estimated to affect as many as 25% of people, although a full- blown phobia is significantly less common. Travel delays, common when flying at popular times, can make the fear of flying worse. Whether or not your fear of flying has developed into a phobia, it can have devastating effects on your quality of life.ReplyDelete
Lern more about psychiatry.... psychiatry , Aerophobia
As a mathematician, I find this subject fascinating. The lack (or diminished) of connectivity between the cerebral hemisphere is what graph theorists call a "graph cut". In network theory, making a "graph cut" alters the behavior of the network radically in a beneficial or a detrimental way as the case may be. Hopefully my question is not too naive but being an outsider to this field, I wonder if many people have studied from a mathematical graph theory perspective the effect of "graph cuts" (in the sense I just described) on the human brain.ReplyDelete
References welcome!


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SYNOPSIS: Based upon the manga by Hisao Mali, Silver centres around the exploits of Jun Shirogane (Shinobu Kandori), a karate expert and undercover police officer who conventionally has also undergone FBI training in the US. After her family who worked for the Secret Service are brutally murdered, she agrees to infiltrate a group of criminals known as the 'Viper's Nest'. …Read More »
Home | Tag Archives: Shinobu Kandori


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DeLAND, Fla. - A rookie Volusia County Sheriff's deputy and his trainer rescued a man from a burning pickup truck Saturday in DeLand.
Wesley Blum, 26, an Army veteran who has served in Afghanistan, and Kenneth Shields, 51, pulled the man from the vehicle, which veered off East New York Avenue before crashing into some trees and coming to rest in the yard of a home.
The truck burst into flames with the driver still inside and witnesses called 911, deputies said.
Blum jumped onto the truck's running board and with the help of an unidentified bystander started tugging on the driver, said the Sheriff's Office, which added that Shields grabbed his patrol car's fire extinguisher and used it to tame the flames in the truck's cab.
The extinguisher emptied, however, and the flames reignited with the driver still trapped inside, deputies said. The fire then intensified, prompting Shields to pull Blum who still had a grip on the driver and was able to pull him free.
The condition of the driver, identified by the Florida Highway Patrol as 21-year-old Robert Wayne Demonte, of Deltona, suffered serious injuries and was taken to Halifax Medical Center. Two others in the car were also hurt in the crash, the FHP said.
Blum was hired by the Volusia County Sheriff's Office in June. Shields has been with the Sheriff's Office for six years.
Copyright 2013 by ClickOrlando.com. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


text:
Question for the Money Doctors
Question submitted on Apr 15, 2010.
QuestionI was recently introduced to the "infinite banking concept" which uses dividend paying whole life insurance as a tool for long term wealth building. Nelson Nash wrote a book about it and an agent at MPG Banking is talking to me about it. Is this a good way to accomplish long term wealth and shield my self from taxation?
Life insurance policies allow you to accumulate cash value income tax-free.
You can later make withdrawals from those policies that are also income tax-free. First, you can withdraw all of your premiums tax free and then you can withdraw
the growth in the policy in the form of policy loans. This is an excellent concept to consider, especially because income taxes may be going up.
This concept would work with both whole life insurance and with variable universal life insurance. The problem with using whole life insurance is that whole life
policies are interest sensitive. What that means is that their returns are probably going to be in the range of bond returns; say 5, 6, or 7%.
On the other hand, in a variable universal life insurance policy, you can own a diversified portfolio of securities. Long-term investors have always looked to the stock market for higher long-term returns. Therefore, I suggest that you compare an illustration of a whole life policy with an illustration of a variable universal life insurance policy. Two companies with excellent variable universal life insurance policies are Manulife and Lincoln.
If you are using the policy primarily for wealth accumulation, you want to make sure that the insurance is the minimum amount you can buy to permit the monthly/annual investment you want to make. If any more insurance is purchased, it is a drag on the investment performance of the policy. Also, choose a rising
benefit while you are accumulating investments in the account. Once you have stopped accumulating investments in the account and are making withdrawals, you
want to choose a level benefit. That also will help reduce costs.
Whatever policy you choose, it is important to be able to make "zero spread loans" What that means is that, for example, you are able to borrow from
the insurance company at 6% and credit your policy account 6% so there is no net cost to you. The zero spread loans should be part of the contract and not changeable by the company's board of directors at a later time.
For additional information visit http://www.360financialliteracy.org/


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