text:
They may have gotten their start as Marky Mark and Puff Daddy, but these two have come a long way! MARK WAHLBERG and SEAN "DIDDY" COMBS sit down with Ellen for a special joint interview!
From rapper to Calvin Klein underwear model, to one of the biggest movie stars in the world, Mark Wahlberg has done it all. He's starred in movies like "Boogie Nights," "The Fighter," "The Departed," "The Perfect Storm" and "The Planet of the Apes." He's also the creator of one HBO's most popular series, "Entourage!"
From rapper to one of the most powerful moguls in Hollywood, Sean "Diddy" Combs helped create some of the biggest names in the music industry. He's also responsible for creating shows like "Making the Band" and "I Want to Work for Diddy." Now he's teamed up with Mark for a new venture in something you might not expect!
Plus, the hilarious CASEY WILSON is dropping by! From "Bride Wars" to "Saturday Night Live," Casey has proven she's one of the funniest women in Hollywood. Now she's the star of the hit show "Happy Endings" -- and she's telling Ellen all about it.
Then, she's one of America's favorite singers, and she has 10 Grammys to prove it! BONNIE RAITT is here to perform her song "Used to Rule the World" from her CD, "Slipstream."
This Wednesday, Ellen's on the top of the charts!


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Why restrict your little wiggleworm in a baby seat when he'd love to stretch those busy legs? Our lightweight confiner lets baby stand, but—unlike bulky play saucers—folds for easy travel! Includes cupholder, snackholder, and five toy loops to keep little ones entertained. Use it at home when you need a hands-free moment, and bring it along for visiting and travel. Very portable; weighs just 7 lbs. Height adjustable, with protective foot mat and carry bag. For use indoors and out. For ages 4 months and up; up to 26 lbs. or until baby starts walking. Imported.For more information, click here.
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A MAN was robbed after being hit from behind by attackers in Clacton.
The 33-year-old man was walking along Old Road when he was hit at about 4pm on Monday.
While he was on the ground the robbers searched his pockets and took a Sony Ericsson mobile phone and cash.
A spokesman for Essex Police said the victim was left shocked and bruised following the attack.
The robbers are described as white, aged between 16 and 20 and about 5 ft 10ins tall.
One was wearing a black Adidas hooded top, blue jeans and black trainers and had a scarf covering his face.
The other was of slimmer build and was wearing a grey hooded top and had a black scarf around face.
Witnesses are asked to call Det Con Luke Howard, at Clacton CID, on 101 or via Crimestoppers on 0800 555 111.


text:
Funeral for fallen soldier postponed to Jan. 12
Published: Friday, January 4, 2013 at 11:58 a.m.
Last Modified: Friday, January 4, 2013 at 11:58 a.m.
The funeral for Army Pfc. Markie T. Sims of Citra, who was killed while on military duty in Afghanistan, was scheduled for Saturday but has been postponed until Jan. 12.
The soldier's mother, Wanda Thompson, said Friday that services for her son now will begin at 1 p.m. on Jan. 12 at the United Baptist Church in Reddick.
She said the delay is necessary because her son's body has not yet been released by the military. She said his body now is expected to arrive Thursday at the Gainesville Airport.
Sims, 20, was killed when an improvised bomb exploded next to his vehicle. He was assigned to the U.S. Army's 38th Engineering Company, 4th Stryker Brigade Combat Team, 2nd Infantry Division.
Sims played football while attending North Marion High School and later graduated from Marion Technical Institute in 2011.
He is survived by Thompson; wife Shakeli Sims; father Henry Sims; grandparents Randolph and Ella Mae Thompson; brothers Henry Sims Jr. and Demarrio Sims, both of Reddick; Defonzio Sims of California; and Henry Lee Daniels of Ocala; and sister Lashay Daniels of Gainesville.
Contact Austin L. Miller at 867-4118 or firstname.lastname@example.com.
Reader comments posted to this article may be published in our print edition. All rights reserved. This copyrighted material may not be re-published without permission. Links are encouraged.


text:
BOCA RATON, Fla. – The Saint Leo men's tennis (3-3, 0-2 SSC) fell to the No.5-ranked Lynn University Fighting Knights (4-0, 1-0 SSC), 8-1, Saturday afternoon from the Perper Tennis Complex.
The Sunshine State conference tilt saw the Green and Gold drop each doubles contest, as well as five of six on the singles side.
The No.21-ranked doubles duo of Matt-Nicholson Lewis and Victor Lozier provided the Lions their best shot at victory, but Lynn's top team of Amaury Van Haelen and Vlad Cirla skated by with an 8-4 win.
On the singles side, Saint Leo battled but only Lozier was able to pull out a victory as he downed Luca Pavanelli in straight sets, 6-4, 6-2.
The Lions will return to the court bright and early Sunday morning as they challenge NAIA's the St. Thomas Bobcats. Opening serve is set for 9 a.m.
For more on the men's tennis team, visit SaintLeoLions.com.


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Hyundai, Kia Busted for Overstating Fuel Economy Claims after EPA Probe
Shane McGlaun
November 2, 2012 8:25 AM
Recipient E-mail
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Hyundai Elantra
Revised Numbers from Hyundai
(Source: Hyundai)
Millions to be paid out to owners over misleading claims
Back in December of 2011,
Consumer Watchdog
called on the EPA to investigate Hyundai over its fuel economy claims. According to Consumer Watchdog, Hyundai claimed that its Elantra was good for 29 mpg in the city and 40 mpg on highway. The problem the organization had with the claims is that it received a higher than usual number of complaints that real-world mileage was in the mid-20 mpg range.
The EPA did investigate Hyundai for misleading mileage claims as well as Kia, and changes in fuel economy estimates are coming as a result of the investigation. Both Kia and Hyundai will be lowering the fuel economy estimates on the majority of their 2012 to 2013 models after EPA testing discovered discrepancies between its data and the company's data.
Hyundai and Kia admitted to overstating the estimated fuel economy on window stickers of about 900,000 vehicles sold since late 2010. The two automakers will reportedly spend millions of dollars to compensate owners for faulty claims of economy.
Hyundai will also have to retract its widely used claim that it leads the industry with four vehicle models able to get 40 mpg on the highway. That statement will be retracted because estimated highway economy on the 2013 Accent, Veloster, and Elantra are being reduced to below 40 mpg.
Some of the biggest losers include the Hyundai Accent and the all-new, redesigned 2013 Hyundai Santa Fe. The Accent saw its 30/40/33 (city/highway/combined) rating drop to 28/37/31. The Santa Fe Sport (2WD) saw a huge drop in its highway rating, going from 21/31/25 (city/highway/combined) to 20/27/23.
Many of the mileage adjustments take Hyundai models from being class leaders to either middle-of-the-pack or lower.
On the Kia side of things, the Soul took the biggest hit as it saw its highway numbers drop by 6 mpg (35 mpg highway to 29 mpg highway).
Overstating fuel efficiency is a significant blunder by the two car companies because gas prices are up, and many people are shopping based on fuel economy claims by the manufacturer. The EPA notes that window sticker values have previously been reduced on only two vehicles sense 2000, so that makes Hyundai's folly even more egregious.
"Given the importance of fuel efficiency to all of us, we're extremely sorry about these errors," said Hyundai Motor America President and CEO John Krafcik. "We're going to make this right."
Krafcik blamed the inaccurate fuel efficiency claims on "procedural errors" in the fuel-economy testing methodology the company used. Hyundai-Kia's combined fleetwide fuel economy average declined from 27 MPG to 26 mpg for the 2012 model year working out to about a 3% reduction.
Krafcik added, "We've identified the source of the discrepancies between our prior testing method and the EPA's recommended approach."
Detroit News
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This blog has been cross-posted from Forbes.
By Amy Rosen,
President & CEO, NFTE
SAPPORO, Japan – A 10 year old in Japan today will likely be hired by a company that does not exist yet.
That's because, according to two researchers from Hitotsubashi University and Nihon University here in Japan, Japanese companies created after 1996 contributed a net positive of 1.2 million new jobs. But older companies shed a net 3.1 million jobs in that time.
The crowd at Sapporo
It's not news that startups are the jobs engine for Japan. It's the same in the United States.
But what is troubling is that according to research from theWharton School at the University of Pennsylvania using World Bank data, Japan, ranks dead last among modern, industrial nations in the average annual entry rate of new enterprises. In other words, Japan is reliant on new companies for jobs but creates the fewest new businesses.
There are many reasons Japan lags in entrepreneurship. One is that Japan dramatically under-utilizes women.
According to the experts at Babson College in Boston, Japan has the second-lowest female entrepreneurship rate in the world. Only Pakistan did more poorly in engaging women in the business of business.
Some of the reasons are cultural. The relationship between women and work in Japan, though evolving, is tense. About half of the women in Japan's workforce leave their jobs when they have children or start families. Only half of those return to the workforce.
According to a report from Goldman Sachs, if Japan were able lift the employment rate of women to equal men, it would add 15% to the nation's GDP. That's an impact equal to two Japanese auto industries.
There is little doubt that keeping women in the workforce or sparking them to create new businesses is a key to Japan's future; Japan's Prime Minister Shinzō Abe said recently, "we must capitalize on the power of women," and "Enhancing opportunities for women to work and to be active in society is no longer a matter of choice for Japan. It is instead a matter of the greatest urgency."
He's right, of course.
And I'm here to help.
I'm in Sapporo, Japan today and I'll be spending the rest of the week here – in Tokyo, Kyoto, Nagoya and other cities – as part of a U.S. State Department arranged trip to speak with women about the entrepreneurship mindset. I'll make the case that entrepreneurial thinking is key to finding jobs in the new world economy.
To be clear, entrepreneurial thinking isn't just about empowering women. When we create more innovators, it will help everyone. In Japan, however, the most visible place to start is with women because there is so much room for growth.
As important as it is to elevate women entrepreneurs and keep the Japanese economy moving, it's just as important to me to spread the word about teaching entrepreneurship. Whether that audience is Japanese women or students in our new NFTE programs in Mexico City and St. Louis, the message is the same – owning your future through entrepreneurial thinking is powerful.
We know that just a fraction of those who learn entrepreneurship will launch and sustain businesses. Even fewer will invent the next big thing and start a global industry.
But some will. And whether it's one in a thousand or one in a million students who find the next big thing, the key is making sure we're teaching ten million people instead of just a million.
Because it's not just that 10 year old in Japan who is counting on entrepreneurs. Every 10 year old is.


text:
Before escaping the office for a summer boat show, I went in search for a pair of flip flops that would be both professional looking as well as comfy. When it comes to ladies footwear, we know it's not always possible to have both.
I decided to contact Chaco because every Chaco flip is built on the APMA (American Podiatric Medial Association) approved LUVSEAT platform that hugs the foot to properly align the body for extra support and a comfortable ride. Okay, so I actually didn't know that, but I thought it would important to mention.
Chaco's EcoTread is a non-marking and the outsoles are made with 25 percent recycled content to leave a minimal footprint, which is nice. For $80 I ordered a pair of women's Leather Flippa EcoTread that are crafted from supple full-grain leather.
After walking the three-day show I was quite pleased with the comfortable fit and feel on the leather lined footbed, plus more importantly, I love the look. A guy version is available, but I doubt it would be as good-looking as my pair.
-Terri Duncan, PDB Magazine
© 2017 Pontoon and Deckboat® Magazine | Published by Harris Publishing, Inc.


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This competitive program will award one cooperative agreement of $350,000 to a nonprofit organization, faith- or community-based organization, or public agency to produce a comprehensive kit that will serve as a resource for the victims' field to support efforts to heighten the public's awareness of crime victim issues during National Crime Victims' Rights Week (NCVRW) in April 2014 and throughout the year. Those applying are urged to begin the application process well in advance of the March 13, 2013 deadline.
Learn more.
© 2016 National Sexual Violence Resource Center – Founded by the Pennsylvania Coalition Against Rape
This site is supported by Grant/ Cooperative Agreement No. 1UF2CE002359-04 from the Centers for Disease Control and Prevention. Its contents are solely the responsibility of the authors and do not necessarily represent the official views of the Centers for Disease Control and Prevention.


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Assessment |
Biopsychology |
Comparative |
Cognitive |
Developmental |
Language |
Individual differences |
Personality |
Philosophy |
Social |
Methods | Statistics | Clinical | Educational | Industrial | Professional items | World psychology |
Clinical: Approaches · Group therapy · Techniques · Types of problem · Areas of specialism · Taxonomies · Therapeutic issues · Modes of delivery · Model translation project · Personal experiences ·
Focal dystonia is a form of dystonia and is a neurological condition that affects a muscle or group of muscles in a specific part of the body causing involuntary muscular contractions and abnormal postures. For example, in focal hand dystonia, the fingers either curl into the palm or extend outward without control. In high level musicians, focal hand dystonia is referred to as musician's dystonia and focal dystonia in sports is commonly referred to as (the) yips. It is believed that all adult onset dystonias are a product of combined genetic factors and environmental modifiers.[1]
The cause of dystonia is not precisely understood. Misfiring of neurons in the sensorimotor cortex, a thin layer of neural tissue covering the brain, is thought to cause contractions. The source of this misfiring may be a result of impaired inhibitory mechanisms during muscle contraction.[2] When the brain tells a given muscle to contract, it simultaneously silences muscles that would oppose the intended movement. In dystonia, it appears that the ability of the brain to inhibit the surrounding muscles is impaired leading to loss of selectivity.[3]
Furthermore, the sensorimotor cortex is organized as discrete "maps" of the human body. Under normal conditions, each body part (such as individual fingers) occupies a distinct area on these cortical maps. In dystonia, these maps lose their distinct borders and overlap occurs.[4] Exploration of this initially involved over-training particular finger movements in non-human primates which resulted in the development of focal hand dystonia. Examination of the primary somatosensory cortex in the trained animals showed grossly distorted representations of the maps pertaining to the fingers when compared to the untrained animals.[5] Additionally, these maps in the dystonic animals had lost the distinct borders that were noted in the untrained animals. Imaging studies in humans with focal dystonia have confirmed this finding.[6] Also, synchronous afferent stimulation of peripheral muscles induces organizational changes in motor representations, characterized both by an increase in map size of stimulated muscles and a reduction in map separation, as assessed using transcranial magnetic stimulation.[7]
The cross-connectivity between areas that are normally segregated in the sensory cortex may prevent normal sensorimotor feedback and so contribute to the observed co-contraction of antagonist muscle groups, and inappropriately timed and sequenced movements that underlie the symptoms of focal dystonia. It is hypothesized that a deficit in inhibition caused by a genetically mediated loss of inhibitory interneurons may be the underlying cause of the deficits observed in dystonia.[8]
While usually painless, in some instances the sustained contraction and abnormal posturing in dystonia may cause pain. Focal dystonia most typically affects those who rely on fine motor skills (musicians, writers, surgeons, etc.) and it is thought that the excessive motor training in these individuals may contribute to the development of dystonia as their cortical maps become enlarged and begin to overlap.[9] Focal dystonia is generally "task specific," meaning that it is only problematic during certain activities.
Notable casesEdit
Musicians affected by focal dystonia include Leon Fleisher, of the Peabody Conservatory of Music, who had suffered from this affliction in his right hand, as did Alex Klein, formerly the first oboist of the Chicago Symphony, Ernestine Whitman, former member of the Atlanta Symphony and currently a professor of flute at Lawrence University, pianist and keyboard player Keith Emerson, guitarist Dominic Frasca, and the pianist Gary Graffman, who performs exclusively with his left hand. In 2005, New Age acoustic guitarist Billy McLaughlin announced via his website that he is suffering from focal dystonia, which severely limits his ability to play right-handed (and as a result, he taught himself to play left-handed). British-Canadian Classical Guitarist Liona Boyd had to give up her professional career as Canada's "First Lady of the Guitar" due to focal dystonia that drastically affected her right hand. Bass guitarist, Andy Billups, who plays with British rock act The Hamsters, has also made a partial recovery from this disorder and continued to play by using modified guitar plectrums to make up for the limited function of his right hand. Classical guitarist David Leisner has recovered the full use of his hand and has returned successfully to the concert stage and recording studio in the early 1990s after a decade of disability. Brazilian singer-guitarist Badi Assad was diagnosed with focal dystonia in 1999 (after having been misdiagnosed with carpal tunnel syndrome). She eventually recovered and was able to resume her career.[10] Tom Adams, a professional bluegrass banjo player, has focal dystonia in his right hand, had to give up playing banjo, and now plays the guitar. Scott Adams, the writer of the Dilbert comics, is also afflicted with focal dystonia of the hand, which impedes his artwork.[11] World champion bagpiper Stuart Cassells, founder of the bagpipe rock group Red Hot Chilli Pipers, announced that he had focal dystonia in the group's blog on 23 September 2011, and left the band because it affected his ability to play.[12] Bass player and instructor Scott Devine discovered that wearing gloves while playing his instrument provides an efficacious workaround to the symptoms of focal dystonia.[13]
This condition is often treated with injections of botox, a commercially prepared form of botulinum toxin. Botox, however, merely targets the symptoms of the disorder and is not a cure for dystonia. Since the root of the problem is neurological, it is thought that sensorimotor retraining activities can enable the brain to "rewire" itself in a manner that can ultimately eliminate dystonic movements. The work of several doctors as Nancy Byl and Joaquin Farias,[14] [15] has shown that sensorimotor retraining activities and proprioceptive stimulation can induce neuroplasticity, making it possible to recover substantial function that was lost from focal dystonia.
- ↑ Hallet, Mark (2011). Neurophysiology of dystonia: The role of inhibition. Neurobiology of Disease 42: 177-184.
- ↑ Hallet, Mark (2011). Neurophysiology of dystonia: The role of inhibition. Neurobiology of Disease 42: 177-184.
- ↑ Hallet, Mark (2011). Neurophysiology of dystonia: The role of inhibition. Neurobiology of Disease 42: 177-184.
- ↑ (1996). A primate genesis model of focal dystonia and repetitive strain injury: I. Learning-induced dedifferentiation of the representation of the hand in the primary somatosensory cortex in adult monkeys. Neurology 47 (2): 508–20.
- ↑ (1996). A primate genesis model of focal dystonia and repetitive strain injury: I. Learning-induced dedifferentiation of the representation of the hand in the primary somatosensory cortex in adult monkeys. Neurology 47 (2): 508–20.
- ↑ (1998). Abnormal somatosensory homunculus in dystonia of the hand. Annals of neurology 44 (5): 828–831.
- ↑ Schabrun SM, & Ridding MC (2007). "The influence of correlated afferent input on motor cortical representations in humans". Experimental Brain Research, 183(1): 41—49, doi: 10.1007/s00221-007-1019-8
- ↑ Hallet, Mark (2011). Neurophysiology of dystonia: The role of inhibition. Neurobiology of Disease 42: 177-184.
- ↑ Rosenkranz, Karin, Katherine Butler, Aaron Williamon, and John C. Rothwell (November 18). Regaining Motor Control in Musician's Dystonia by Restoring Sensorimotor Organization. The Journal of Neuroscience 29 (46): 14627–14636.
- ↑ Badi Assad's web site
- ↑ includeonly>Sordyl, Samantha. "Scott Adams, Drawing the Line", The Washington Post, 2005-05-10. Retrieved on 2010-05-02.
- ↑ http://www.redhotchillipipers.co.uk/spanbNewsbspan/tabid/73/Default.aspx?newsItem=98
- ↑ http://scottsbasslessons.com/odds-and-sods/the-gloves
- ↑ Farias J, Yoshie M. Treatment efficacy in an ecologically valid neuropsycological treatment program of 120 professional musicians with focal dystonia. Galene Editions. Amsterdam 2012. I.S.B.N.: 978-84-615-5124-8.
- ↑ Farias J ,Sarti-Martínez MA. Title: Elite musicians treated by specific fingers motion program to stimulate propiceptive sense. Congreso Nacional De La Sociedad Anatómica Española. Alicante (España). proceedings pag110. Publication: European Journal of Anatomy
- Tubiana, Raoul, Amadio, Peter C.; Medical Problems of the Instrumentalist Musician; UK; Martin Dunitz (2000); 295-397
- Rich, Robert F.; Mackin, Evelyn; Callahan, Anne; A. Lee Osterman; Terri M. Skirven; Schneider, Lawrence J. (2002). Hunter, Mackin & Callahan's Rehabilitation of the Hand and Upper Extremity (2 Volume Set), 2053–2075 ("Focal Hand Dystonia"), St. Louis: Mosby.
- Farias, Joaquin. "Intertwined. How to induce neuroplasticity. A new approach to rehabilitating dystonias". Galene Editions 2012.
- Farias, Joaquin. "Rebellion of the body. Understanding musician's Focal dystonia". Galene Editions 2004.
- (2007). Curing Focal Dystonia or How to Play the Guitar with Large Muscles. Guitar Review 133: 10–15.
- Pascual-Leone A (2001). The brain that plays music and is changed by it. Ann. N. Y. Acad. Sci. 930: 315–329.
- (2007). What Every Guitarist Should Know: A Guide to the Prevention and Rehabilitation of Focal Dystonia. Guitar Review 133: 2–9.
|This page uses Creative Commons Licensed content from Wikipedia (view authors).


text:
"Game changer" is a term you hear often when people talk about how technology has changed their industry.
R.G. Barry Promotes Ackard
 R.G. Barry Corporation has announced the appointment of Greg Ackard as senior vice president of sales. Ackard most recently served as vice president of national accounts for the accessories footwear marketer.

 Broadband Expands Gallagher's Role
 Broadband Enterprises has announced an expanded role for Joe Gallagher, the company's executive vice president of U.S. sales. In addition to his current responsibilities, Gallagher has been named executive vice president of international sales, a newly-created position.

 JAZD Names New SVP
 JAZD Markets, a provider of online marketing-as-a-service platforms, has named David Southwick senior vice president of sales and service. Southwick previously served as chief operating officer and head of sales at the Aberdeen Group.

 Arbitron Names Behbehani New EVP
 Arbitron has announced the appointment of Taher G. Behbehani to the newly-created position of executive vice president, chief strategy and business development officer. Most recently, Behbehani served as vice president of business affairs at Time Warner Cable.

 Nexius Appoints SVP of Sales
 Nexius, a provider of products and services for communications providers, has appointed Steve Durante senior vice president of sales. Durante joins Nexius from IBM, where he was sales vice president of the Americas for Tivoli Vallent.

 Mpex Names Wiggins Chief Business Officer
 Mpex Pharmaceuticals has announced the appointment of Mark Wiggins as chief business officer. Wiggins comes to Mpex from Biogen Idec, Inc. where he most recently served as executive vice president of business development and was a member of the executive committee.

 Victory Fills Business Development Role
 Victory Marketing Group has named Paul Bartolotta as its new Director of Business Development. Bartolotta most recently served as director of North American business for sanofi-aventis.


text:
Anyone is from Poland or Czech Republic? I am going in the 22 with my girlfriend, I will be in Warsaw, Wroclaw, Krakow and Prague, if there is anyone up for a beer, let me know! Cheers
Also if anyone has been there, anything to advice?
micseydel wrote:You could meet stranac!
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Ok, so I know I'm going to do the pork shoulders for the pulled pork sandwiches and I'm thinking not everyone likes pork so what about beef?
Has anyone done a beef roast in the same manner for pulled beef sandwiches??
If you have what cut of meat did you use? How big was it? What temp did you bring it to and how long did it take? What kind of mop sauce did you use? What sauce did you serve it with?
I know I asked a lot in this little space, but I sure would like everyones input / ideas.


text:
Reinstall Backtrack it will work afterwords.
I was running windows vista and I had hdd installed back track 5 r2. When I was booting my PC there were option to boot either operation system. After I installed windows 8 preview version that menu does not appear anymore. I tried to boot from cd and after startx loading screen appears but jumps back to black screen where write startx. I kinda remember I had this problem before and had solved but not sure how was it?
FYI: hp dv9000 core 2 duo 2.81 gpu disabled cuz fried
Reinstall Backtrack it will work afterwords.
Back|track giving machine guns to monkeys since 2007 !
Do not read the Wiki, most your questions will not be answered there !
Do not take a look at the: Forum Rules !
I agree with Sickness. Backtrack must be lastly installed. If you can configure ur menu to not boot previous MBR it would help. Or configure to not rememeber last boot.


text:
Submit News
Report: Apple Nears Purchase of Top Mobile Flash Memory Controller Maker
Jason Mick
December 13, 2011 12:34 PM
Recipient E-mail
Sender E-mail
Anobit acquisition could be the biggest purchase of a hardware maker in Apple's history
Apple, Inc. (
) can't hide its love flash. Apple is immersed in a over decade long passionate affair with NAND flash memory, which it uses for storage across all of its mobile devices and in its computer SSDs.
I. Apple Pulls an OCZ
Now Apple is reportedly in talks to absorb a major part of its flash supply chain, and is reportedly in talks to purchase Israeli flash memory fabless chipmaker Anobit.
Anobit is a small firm founded in 2006 in Herzeliya Pituach -- an affluent beach-side district on central Israel's Mediterranean coast. Today the company operates subsidiaries in the U.S. and South Korea. Its core business is the tiny chips that allow super-fast, reliable access to flash memory, flash memory controllers.
Apple already licenses Anobit's controllers for use in its iPhone, iPad and
MacBook Air
A good flash controller is incredibly valuable to SSD makers or companies who use flash components in their devices. Just ask OCZ Technology Group Inc. (
), whose SSDs have been dominating the enthusiast market, thanks to their slick Indilinx controller, which suffers little of
the bugginess
of LSI Corp. (
SandForce's controllers.
OCZ apparently found the South Korean controller maker Indilinx
so invaluable that it bought it
(and its 20 patents) for $32M USD in stock. This purchase was followed in turn by LSI's $322M USD acquisition of SandForce, a deal driven by SandForce's broad market base, which offset its poor controller stability.
Now Apple is expected to follow in suit, potentially folding in Anobit to prevent competitors from gaining access to its technology. News of the deal
[translated] from the the Israeli publication
Reportedly the acquisition price could hit as high as $400M-$500M USD, a boon for Anobit investors, who have thus far poured $97M USD in venture capital into the startup. The acquisition would also grant Apple control of Anobit's 21 patents (and the 74 more currently in the submissions process).
II. Longevity, Performance Differentiate Anobit's Mobile, Enterprise Controllers
Thus far Apple's only past hardware acquisitons have been slightly smaller -- a
$278M USD purchase of PA Semi
in 2008, and a
$121M USD purchase
of Intrinsity in 2010. If the purchase of Anobit proceeds, it would be the first major acquisition in the young tenure of
new CEO Tim Cook
Anobit has a very valuable specialty, which could drive Apple to make the purchase. Reportedly, its technology for detecting "bad" memory cells in MLC (multi-level cell) flash memory is the best in the industry. That allows cheap MLC to replicate the typically far-better endurance of expensive SLC (single-level cell) flash. Long-term longevity is
still a concern for flash drives
, so this is a very valuable technology.
That comes in handy for Anobit's enterprise offerings, which promise "4 Terabytes write per day for 5 years". With Apple
increasingly deploying storage-heavy large-scale data centers
to support
technologies like the iCloud
, this could come in handy. If the reliability issues could be removed, Apple could switch its servers over to using solid state drives (flash prices allowing) removing one more piece of the latency equation for its cloud users.
Anobit's enterprise-ready SSD controllers could give a boost to Apple's iCloud.
The core specs on Anobit's embedded controller (used in the aforementioned MacBook Air, iPad, and iPhone) are pretty sweet to:
666 MB/s data transfers
Works with up to 256 GB / 16 dies of NAND
"Ultra low" power consumption
Support for 20nm and sub-20nm NAND
Dual host interface (provides faster data piping to the rest of the system)
Anobit claims its controller is the "highest performance" tablet or smartphone flash storage controller. We're sure some other companies would disagree with that assessment, but it's at least safe to say that Anobit is no performance slouch.
Anobit is a fabless firm, which means it lacks chip production capacity of its own, instead paying third parties chip fabricators like GlobalFoundries Inc. to actually put its proprietary designs onto chips.
We'll keep you updated if Apple goes through with its reported plan to fold in this crucial piece of its flash supply chain.
Calcalist [Translated from Hebrew]
"We don't know how to make a $500 computer that's not a piece of junk." -- Apple CEO Steve Jobs
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text:
For Reporters / December 9, 2013
For Immediate Release: December 6, 2013
Contact: Monika Johnson Hostler, President, firstname.lastname@example.com
National Alliance to End Sexual Violence Statement:
A National Perspective on Recent High-Profile Sexual Assault Cases
Steubenville. Chapel Hill. Maryville. Tallahassee. Billings. Nashville. Storrs. Across our nation incidents in cities, towns and universities have put sexual assault in the headlines along sports teams and fraternities. As national leaders in the efforts to respond to sexual violence and support survivors, it is deeply disturbing to us that as a nation we've made seemingly little progress in addressing this issue. Why haven't things changed? Why are we still blaming victims?
For the almost 1 in 5 women who have been the victim of an attempted or completed rape in this country, national commentary must be, in large part, an excruciatingly painful burden added to the already tough work of living with the devastating impacts of the crime. Our hearts go out to each survivor, and we promise that you are not alone, even though it may feel that way much of the time.
There is also no escaping the facts, and we ask everyone to acknowledge them:
- A sex crime, a crime against a person, is charged as a crime against the state. The final decision of whether to move forward belongs to the prosecutor and that decision is based on the perceived quality of the evidence. Many survivors are scared of pursuing criminal charges, and cases rarely go forward without their cooperation. A prosecutor's decision to drop a case does not necessarily mean the accused is innocent.
- Probable cause is needed. Not charging an individual does not mean the victim was lying or that a crime did not occur.
- Federal data sources suggest that there is little or no change in the rate of prosecution, conviction, and incarceration for rape in the last two decades. Of 100 forcible rapes that are committed:
o Approximately 5-20 will be reported;
o 0.4 to 5.4 will be prosecuted;
o 0.2 to 5.2 will result in a conviction;
o Only 0.2 to 2.9 will yield a felony conviction;
o Only 0.2 to 2.8 will result in incarceration of the perpetrator;
o Only 0.1 to 1.9 in prison and 0.1 to 0.9 in jail.
- Sexual trauma affects survivors in many ways, including memory and the ability to recall details of the crime.
- Individuals cannot legally consent to sex when they are incapacitated.
- False reporting of rape is rare.
There is also no escaping some very tough questions, and we ask everyone to wrestle with them:
- Can our heroes be cruel and still seem nice and be good athletes and coaches?
- What facts and feelings do we use to form an opinion about an incident of sexual assault?
- How and why do we try to distance ourselves from the experience of victims?
- What makes it so difficult to believe someone who reports a sexual assault?
- Can we participate in the status quo when so many around us are suffering and need us to stand with them?
- How does the culture of male-centered activities such as sports teams and fraternities create an atmosphere that allows sexual violence?
- How are racism and rape intertwined?
- What leads "ordinary" young men and boys to engage in behavior that profoundly lacks empathy?
- How much weight and responsibility do we place on victims reporting sexual assaults when comments are made about "ruining" the lives of athletes and those in positions of power?
Those of us who have been working in the anti-sexual violence movement for decades know that a culture based on male dominance plays a key role in sexual violence. Unless and until we are willing to examine all of the ways this plays out in our society, including a "boys will be boys" mentality, the change that must occur will not. Football towns will continue to sweep sexual violence under the rug with cheering fans echoing in the background; institutions of higher learning will continue to follow the letter rather than the spirit of the law when responding to sexual assault; and too many young women will have their dreams threatened.
As we gather in stadiums and around television sets over the next few weeks to watch the big game, we ask you to consider that someone deeply hurt by sexual violence sits somewhere very nearby. Consider the possibility that the person might be your daughter, your girlfriend, your wife, your friend, your mother, your brother or your son. And ask yourself if you can contribute in some way, whether it be by speaking up when you hear inappropriate comments or by encouraging your friends or business partners to make a donation to your local rape crisis program. We call upon members from every facet of society to take a stand against sexual violence today by making a decision to consciously avoid the trap of victim-blaming.
iBlack, M.C., Basile, K.C., Breiding, M.J., Smith, S.G., Walters, M.L., Merrick, M.T., Chen, J., & Stevens, M.R. (2011). The National Intimate Partner and Sexual Violence Survey (NISVS): 2010 Summary Report. Atlanta, GA: National Center for Injury Prevention and Control, Centers for Disease Control and Prevention. Available at: http://www.cdc.gov/ViolencePrevention/pdf/NISVS_Executive_Summary-a.pdf
iiLonsway, K.A. & Archambault, J. (2009). The 'Justice Gap' for Sexual Assault Cases: Future Directions for Research and Reform. Journal of Violence Against Women. Available at: http://counterquo.org/assets/files/reference/Justice%20Gap%20for%20Sexual%20Assault%2005‐25‐10.docx.
iiiThe NAESV gratefully acknowledges the U.S. Department of Justice, Office of Justice Programs, National Institute of Justice, for allowing us to reproduce, in part or in whole, the video Interview with Dr. Rebecca Campbell on the Neurobiology of Sexual Assault. The opinions, findings, and conclusions or recommendations expressed in this video are those of the speaker(s) and do not necessarily represent the official position or policies of the U.S.
Department of Justice.
ivLonsway, K. A., Archambault, J., & Lisak, D. (2009). False reports: Moving beyond the issue to successfully investigate and prosecute non-stranger sexual assault. The Voice, 3(1), 1-11. Retrieved from the National District Attorneys Association: http://www.ndaa.org/pdf/the_voice_vol_3_no_1_2009.pdf and Heenan, M., & Murray, S. (2006). Study of reported rapes in Victoria 2000-2003: Summary research report. Retrieved from the State of Victoria (Australia), Department of Human Services: http://www.dhs.vic.gov.au/__data/assets/pdf_file/0004/644152/StudyofReportedRapes.pdf


text:
Welcome to a world of outstanding mobility, welcome to the world of Sixt. With almost 100 years of experience and know-how, Sixt is today more than just one of the leading car rental companies in the world.
In over 4000 locations in more than 100 countries, Sixt offers a full range of high-quality mobility solutions - from compact economy cars to prestigious limousines and luxury cars, Sixt will always have the perfect car for a great price to suit its customers requirements.
You earn 500 Extra points each time at normal rates at Sixt worldwide and 1000 Extra points on Sixt Limousine rentals. Certain rates are excluded from points collection and reward promotions cannot be combined.
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Click here if your points have not been registered after 3-6 weeks
Scandinavian Airlines © 2016


text: Three decorated halls in the Empire style that dominated the Napoleonic era give the restaurant the intimate character that guests treasure. The "Imperatrice" hall can accommodate up to sixty people. The Greenhouse, bursting with green plants, and the Centre Hall, with its stonework, can easily accommodate twenty guests. The Bonaparte cuisine is inspired by the French countryside. The menu, with its array of tempting suggestions, is made to satisfy the most diverse palates at very reasonable prices.


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text:
An asthma action plan (or management plan) is a written plan that you develop with your child's doctor to help control your child's asthma.
The goal of an asthma action plan is to reduce or prevent flare-ups and emergency department visits through day-to-day management. Having a written step-by-step plan in place provides clear instructions so you and your child can:
Experts recommend using a written plan as part of asthma treatment. Following a written asthma action plan can help your child do normal everyday activities without having asthma symptoms.
Each person's experience with asthma is different, so each action plan will be, too. A key part of any action plan will detail what needs to be done during a flare-up. For students, this may include permission for them to take quick-relief medicine (also called rescue or fast-acting medicine) at school. The action plan also should clearly state when to seek emergency care.
Although they can be organized in a number of ways, many action plans use the "zone system," which is based on the red, yellow, and green colors of a traffic light. This is the same color system used on peak flow meters. Action plans use symptoms, peak flow readings, or both to help you determine the zone your child is in:
The color system makes it easy for kids and parents to quickly figure out which instructions apply to a child's peak flow meter reading. Your child's "personal best" peak flow reading is an important measurement to include on the plan so that you'll have something to compare the new numbers to.
Asthma action plans may also include:
It's important to have all of this information in one place so that you (as well as your child's teachers, relatives, and caregivers) can respond as needed, even in stressful situations.
Your child's action plan will be most effective if you make yourself familiar with it before your child has a flare-up. Follow the advice in it to avoid flare-ups.
Your child should be familiar with the plan, too, and older kids should know which steps they can take themselves and when they should get help.
The action plan should go everywhere your child goes. Keep a copy at home in a well-known spot and give one to the school nurse, teachers, and anyone else who cares for your child. Offer to discuss the plan so they'll be comfortable following it.
Also, revise the plan whenever dosages for your child's medicines change. Review the plan with your doctor at least every 6 months, or more often if symptoms happen more than they used to.
The plan also might need to be updated if your child doesn't seem to need quick-relief medicines as often. Any time the action plan is changed, give new copies to anyone who has one.
Note: All information is for educational purposes only. For specific medical advice, diagnoses, and treatment, consult your doctor.
© 1995-
Images provided by iStock, Getty Images, Corbis, Veer, Science Photo Library, Science Source Images, Shutterstock, and Clipart.com


text:
Liberal Democrat MP for Leeds North West, Greg Mulholland, has led the tributes to Team GB's Zoe Gillings, from Otley, who on Sunday narrowly missed out on a place in the women's snowboard cross finals at the Winter Olympics.
Gillings came fourth in a nail-biting semi-final in Sochi, Russia, where she was overtaken right at the very end by Italy's Michela Moili in a photo finish.
In her post-race interview, Gillings said it was a shame to have so narrowly missed out.
Zoe said: "I thought I'd actually got through at one point because one of the officials said that I was through. But then it turned out I wasn't, which was a real shame to miss out on the final by that small amount, but I rode as hard as I could, as fast as I could, so that's all I can really do."
Mr Mulholland said: "It would have been fantastic to see one of Otley's own go all the way and win a medal, but sadly it wasn't to be!
"It's tough enough going through months and years of training. To then be selected for Team GB's Winter Olympics squad and make it all the way to the semi-finals is an absolutely fantastic achievement. Zoe has done Leeds proud."


text:
You won't be able to dismiss this by usual means (escape or click button), but you can close it programatically based on user choices or actions.
"I am completely satisfied and pleased with the design and quality of these programs. Thanks so much to the Wedding Paper Divas staff for a job well done! I know that my guests will be wowed!"


text:
The Family Drug Courts program builds the capacity of states, state and local courts, units of local government, and federally recognized tribal governments to either implement new drug courts or enhance pre-existing drug courts for individuals with substance abuse disorders or substance use and co-occurring mental health disorders, including histories of trauma, who are involved with the family dependency court as a result of child abuse, neglect, and other parenting issues.
Learn more [1].
Links:[1] http://www.ojjdp.gov/grants/solicitations/FY2013/FamilyDrugCt.pdf


text:
DANNY Talbot reckons he handed himself a monumental confidence boost ahead of the Commonwealth Games by mixing it with the world's best at last weekend's Sainsbury's Glasgow Grand Prix.
The Trowbridge Tornado was fifth (20.44) in the 200m at last week's Diamond League meeting and the 23-year-old proved to himself that he can keep up with the fastest around, including current world number one Warren Weir.
Jamaican ace Weir (20.30) finished second behind Panama's Alonso Edward (20.25) and Talbot, who is currently at the England squad's Manchester holding camp ahead of the Commonwealth Games, which get underway next week, believes that he can challenge the world's top 200m stars in Glasgow.
"I came fifth against a world-class field and wasn't that far off the top guys in the world. I'm confident I can go there and challenge Warren Weir, like I did on the weekend," said Talbot.
"Alonso Edward won, who is third in the world this year, Weir was second, Curtis Mitchell came third, who was third at the World Champs last year, and Wallace Spearmon came fourth, so it was pretty much four of the best in the world this year.
"I wasn't really that far behind them – I was only a tenth behind Weir and Curtis Mitchell and Spearmon only got me on the line by out-dipping me, so it was a massive confidence boost.
"The race went amazingly. It was probably the best bend I've ever had and then I got on to the straight.
"Spearmon's one of the fastest of all-time and I was against two of the fastest in the world this year, so I almost expected them to go past me and I didn't really believe that I could beat them.
"But now I've gone through that and I know I can be up there with them. That's just given me a massive confidence boost for the Commonwealth Games and if I was with Weir then, there's no reason I can't be with him in the final, if I make it."
Track star Talbot became a British champion earlier this month and is aiming for the podium in Glasgow.
He added: "I want to go into championships with the belief that I can win medals. The only individual championships I've done at senior level were the Europeans (in 2012) and I was ranked 15th going in to it on season's best but I managed to come third."
Talbot was this week confirmed in the Great Britain squad for next month's European Championships in Zurich.
Rachel to live the dream in Glasgow
MELKSHAM'S Rachel Williams will realise her dream of swimming at the Commonwealth Games next week.
The 20-year-old, who has earned a place in Wales' 4x100m freestyle relay team, will take to the water on the second day of competition in Glasgow next Thursday (July 24), with the final set to place that evening.
Williams trains at the University of Bath's national centre for swimming and says that she can't wait to take on the world's best at the Tollcross International Swimming Centre.
"This has been my dream since I was 15. I was 16 when the Dehli Games were happening (in 2010) and I knew that it was too soon for me that year and 2014 would be the one to aim for," she said
"Relay isn't something that happens very often at the top level but I've done it with some of the Welsh girls and the GB girls in the past, so I can't wait to do it in Glasgow."
FOR MORE SPORTS NEWS, REPORTS & PICTURES SEE FRIDAY'S WILTSHIRE TIMES AND FOLLOW US ON TWITTER @WTSport


text:
Children's Hospital of Wisconsin offers a truly unique approach to asthma, allergy and immunology diagnosis and care. With clinic locations in southeast Wisconsin and the Fox Valley, our board-certified, award-winning specialists provide comprehensive care for the entire family.
Make an appointment with our asthma, allergy and immunology team.
We offer convenient clinic locations in southeast Wisconsin and the Fox Valley.
Meet our asthma, allergy and immunology team.
The Children's Hospital of Wisconsin team is the only one of its kind on the combined Children's-Froedtert campus. That means we diagnose and treat both adults and children, which can be especially helpful for families with multiple allergies or asthma-sufferers.
We offer specialized services that allow us to develop unique treatments for patients with complex conditions, including allergy and respiratory care. These include our Primary Immunodeficiency Program, Asthma Plus Program and clinical nutrition services.
Children's Hospital of Wisconsin partners with the Medical College of Wisconsin as a regional and national (international) leader in the field of immunology research and treatment. We are a Jeffrey Modell Diagnostic Center for Primary Immunodeficiencies. That means we offer a full range of treatments for immune diseases. We are also dedicated to research that helps us improve our diagnostic testing and care.
In addition, our very own Clinical Immunodiagnostic & Research Laboratory (CIRL) offers some of the most advanced testing in the country. As a result, we get quicker, better results for you and your children.
Children's treats the full range of asthma, allergy and immune disorders, including:
Read more about asthma, allergy and immune disorders
Our dedicated, experienced team is trained to provide all aspects of your child's care and treatment, which may include:
Read more about asthma, allergy and immune disorder treatment
Children's is a leader in asthma, allergy and immune disorder research. We actively develop new solutions and research cures. As a result, we bring your whole family the very latest and best treatments and medication available. Among our ongoing efforts are:
A joint effort between Children's Hospital of Wisconsin and the Medical College of Wisconsin, the CIRL combines academic, scientific and technical strengths to provide state-of-the-art clinical and research procedures.
Read more about research
Our team of specialists diagnoses and treats complex primary immune deficiencies (non-AIDS) in both children and adults.
Read more
Children's Hospital and the Wisconsin State Laboratory of Hygiene lead the nation and make Wisconsin the first state to pilot a newborn screening test program for severe combined immunodeficiency.
Since 1987, the Jeffrey Modell Foundation has worked to build diagnostic centers across the country to research and improve treatments for primary immunodeficiencies.


text:
Buchholz looks for elusive state finals berth
Published: Thursday, February 21, 2013 at 9:09 p.m.
Last Modified: Thursday, February 21, 2013 at 9:09 p.m.
The previous two years, the Buchholz girls basketball team was expected to make it to Lakeland for the state tournament and did.
Class 7A state semifinals
Today's games in Lakeland
GAME 1: Buchholz vs. Tampa Freedom, 2:30 p.m. Watch online at bit.ly/YJJ0dx
GAME 2: Haines City vs. Davie Nova, 4 p.m.
Problem was, the Bobcats came home empty-handed.
Losing four starters from last year's state semifinal squad, expectations were a lot lower this season. But that lone returning starter, Jessica Thomas, knew better.
"A lot of people are probably doubting us since we lost so many people, and it will be hard," Thomas said during her University of Miami signing ceremony in November. "It is a very different type of team, but as the season goes on, we will learn how to adapt and learn how to win."
Well, guess who is back in Lakeland?
Led by Thomas, the No. 2 Bobcats (26-4) have a 2:30 p.m. date with No. 4 Tampa Freedom (25-3) in today's Class 7A state semifinals at The Lakeland Center. That Buchholz has reached the final four three straight years is an accomplishment in itself, but make no mistake, the goal is to win it.
"I'm sure a lot of people thought we wouldn't make it this far, but like I said at my signing, just expect the unexpected," Thomas said Wednesday. "The first year it was a goal just getting to Lakeland. For two years we have had that. This year the goal is just to win it all and bring it back home."
The winner of Buchholz-Freedom will play the winner of today's other 7A state semifinal (Haines City-Davie Nova) in Saturday's championship at 5:05 p.m.
Thomas is a huge reason why Buchholz has another shot. The senior guard, who averages 30 points a game, had 47 with seven 3-pointers in an 84-79 overtime win at Viera in the Region 1 final on Saturday. She made three free throws with 2.1 seconds left to force OT.
"I think the girls realized when we are up we have to stay up and make the fight a little easier for us," said Buchholz coach Rebecca Williams. "We were up by nine and kind of let them back in the game with turnovers. That type of game is going to help us down the stretch these next two games."
"It brings a lot of confidence towards myself and our team," Thomas said of the win. "They finally realize I am there for them and we are there for each other."
The Bobcats have also had great play from junior guard Jaz Rollins, also a 3-point threat who averages 16 points per game. Freshmen Keona Thompson (12.0 rpg), Chelsea Clark and Aniya Noble all contributed in the win over Viera.
"Probably no one in their right mind would put three freshmen in at the same time," Williams said. "They are young, but I told them to leave it all out on the floor, and they did that."
Freedom, which lost two of games at the Rob Moramarco Challenge at Buchholz in January, is led by 6-foot-2 center Faith Woodard, a Georgetown signee, who averages 26 points and 10 rebounds a game.
Last year Buchholz came into Lakeland ranked No. 1 and the favorite to win it all. But in its 61-57 state semifinal loss to Haines City, Buchholz struggled from the start, going 2-of-16 from the floor and 0-of-10 on 3-pointers to score just five points in the first period. The Hornets also had a huge edge at the free-throw line, hitting 27-of-32 for the game.
"I learned it is not always the better team that wins," Williams said. "You can't go in there thinking that you got it as soon as you get there. You got to work for what you want. This group of kids here is my unexpected group. I told them nobody expected us to be where we are right now. If we keep faith, play hard and worry about our team, we should be fine."
Reader comments posted to this article may be published in our print edition. All rights reserved. This copyrighted material may not be re-published without permission. Links are encouraged.


text:
Ask anyone who has seen Dallas Theater Center's production of God of Carnage what the most memorable moment in the play is, and you will get a chorus of unanimity — guaranteed. If you've seen it, you know. If you haven't, spoiler alert!
It comes about 20 minutes in. A graceful socialite, played by Sally Nystuen Vahle, announces she's feeling queasy. Then, with almost no warning, she blows chunks. Throws up. As in projectile vomiting that seems to go on forever. And is milky. And has big pieces in it (apples and pears, if you follow the dialogue). And it gets everywhere.
The process of making the scene work was a confluence of Vahle's stagecraft and the efforts of John Clauson, the props designer, and his team. And it took a lot of trial-and-error.


text:
MISSION is a new drug discovery and development company based on the pioneering research of Professor Stephen Jackson, Head of Cancer Research UK Laboratories at The Gurdon Institute, University of Cambridge. He is an expert on cellular responses to DNA damage and previously founded KuDOS Pharmaceuticals, which was acquired by AstraZeneca in 2006 for $210m. Professor Jackson will become Chief Scientific Officer of MISSION, and the company will be led by Dr Niall Martin, previously head of KuDOS Pharmaceuticals. Dr Xavier Jacq and Dr Keith Menear will also join the founding team, having both previously held key scientific roles at KuDOS Pharmaceuticals.
MISSION''s goal is to translate new molecular understandings of human cell biology and enzymes into drugs that will markedly improve the management of major life-threatening diseases. The main focus of MISSION's research and development activity will be in oncology, where it will build a strong drug discovery platform against enzymes in the ubiquitin pathways that control cellular responses to DNA damage. Targeting this exciting area of biology may also have potential value in other therapeutic indications.
Simon Kerr, Innovations' Director of Healthcare Ventures, will join the Board of MISSION as a non-executive director.
Susan Searle, Chief Executive Officer of Innovations, said:
"This first investment in a Cambridge company is a significant step for Innovations. We are delivering on our objective of broadening our portfolio to include technology from Oxford, Cambridge and University College London. We are excited by this opportunity and to be working with such a strong team under the leadership of Professor Jackson and Niall Martin."
Niall Martin, Chief Operating Officer of MISSION, said:
"This is a great opportunity to continue to work with Professor Jackson to deliver high quality science and to develop drugs that will have a real impact on disease. We are also pleased to have the backing of such a strong investor syndicate as we develop MISSION to become a leader in its field."
Imperial Innovations (www.imperialinnovations.co.uk)
020 7594 6589
Susan Searle, Chief Executive Officer
Diana Crisp, PR Manager
MISSION Therapeutics Ltd (www.missiontherapeutics.com)
01223 497451
Niall Martin, Chief Operating Officer
College Hill 020 7457 2020
Adrian Duffield/Rozi Morris/Tim Watson
J.P. Morgan Cazenove 020 7588 2828
Michael Wentworth-Stanley/Paul Park
Innovations creates, builds and invests in pioneering technologies addressing global problems in healthcare, energy, engineering and the environment. It combines deep understanding of science and technology with commercial acumen and strong investment expertise.
Innovations supports scientist-entrepreneurs in the commercialisation of their ideas by:
- leading the formation of new companies and providing facilities in the early stages;
- providing significant investment and encouraging co-investment to accelerate the transition from R&D to products;
- providing operational expertise; and
- helping to recruit high-calibre industry figures and experienced entrepreneurs as executive management and Board members.
In December 2010 Innovations raised £140m to accelerate the making of, and increase the size of, investments in companies established under its existing intellectual property pipeline agreement with Imperial College London. The Group also announced its intention to invest in companies founded by or based on technology from the University of Oxford, the University of Cambridge and University College London.
Innovations has already achieved significant success with its early investments; for example its £1.5m investment in obesity drug developer Thiakis could return up to £22m, following its sale for £100m in 2008, while the sale of Respivert, a small molecule drug discovery company, resulted in Innovations realising £9.5m, a 4.7x return on investment.
In the year to 31 July 2010, Innovations invested £14.0m in 20 ventures, helping to launch three new companies. With a technology portfolio of more than 80 companies, Innovations' most advanced assets include:
- Circassia: Innovative vaccines for the treatment of a wide range of allergies
- Nexeon: Advanced materials that extend the cycle life and significantly increase capacity of rechargeable batteries
- Veryan: Stents inspired by the human vascular system
- PsiOxus Therapeutics: Developing a pipeline of small molecule therapeutics for the treatment of wasting diseases and cancer.
- PolyTherics: Biotechnology company that applies precision chemistry to develop protein and peptide-based drugs
- Cellmedica: Cell therapy company working on new techniques to cure human diseases based on cellular immunotherapy
- Evo Electric: Develops and manufactures advanced electric machines, hybrid drive trains and generator sets for a wide range of transportation and mobile power applications
Following Innovations announcement in December 2010 of the Group's broader remit to work with Cambridge Enterprise, Oxford Spin-out Equity Management and UCL Business, Innovations has recently made investments in Stanmore and Autifony both of which are linked to University College London. This MISSION investment represents the first investment into a Cambridge linked company.
MISSION Therapeutics Ltd
MISSION Therapeutics was founded in 2011 by a team of scientists including Professor Steve Jackson, Dr Niall Martin, Dr Xavier Jacq and Dr Keith Menear, along with founding institutes Cancer Research Technology and Cambridge University. Its activities are based on the research of Professor Steve Jackson, Professor of Biology at the University of Cambridge and Head of Cancer Research UK Laboratories at The Gurdon Institute in Cambridge.
The company has received £6 million in Series A funding from a strong venture capital syndicate comprising Sofinnova Partners, Imperial Innovations, SR One and Roche Venture Fund.
MISSION Therapeutics is developing a broad platform of technologies for the discovery and further development of first-in-class modulators of enzymes involved in cancer and other diseases. The company will predominantly exploit the new and exciting research emerging on the ubiquitin pathways that control cellular responses to DNA damage. MISSION will develop drugs to inhibit the proliferation of tumour cells, building on the scientists' experience in exploiting the concept of synthetic lethality, now an established and powerful mechanism to selectively kill tumour cells.
The company is based at the Babraham Research Campus, around seven miles south of Cambridge.


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Pete Earley
Award-winning local author Pete Earley was interviewed for BookCast by Fairfax County Public Library Director Sam Clay. BookCast is sponsored by Dominion Resources through the Fairfax Library Foundation.
Former Washington Post reporter Pete Earley is the author of nine non-fiction books and three novels including the New York Times bestsellers Family of Spies: Inside the John Walker Spy Ring and COMRADE J: The Untold Secrets of Russia's Master Spy In America After the End of the Cold War as well as Edgar winner for his true crime book Circumstantial Evidence: Death, Life, and Justice in a Southern Town.
His book, CRAZY: A Father's Search Through America's Mental Health Madness was one of two finalists for the Pulitzer Prize in 2007. It describes his attempts to help his college age son, Mike, after he becomes ill with bipolar disorder and is arrested. It also chronicles a year that Earley spent at the Miami Dade County Jail where he followed persons with mental disorders, who had been in jail, out into the community to see what sort of services they received. His book also won awards from Mental Health America and the American Psychiatric Association.
Pete Earley was cited by Washingtonian Magazine in a cover story entitled, "Top Journalists: Washington's Media Elite," as one of a handful of journalists in America who "have the power to introduce new ideas and give them currency."


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NiteLite Promotions is proud to present Sinbad live at The Chicago Theatre on Friday, February 15th, 2013 at 8:00pm.
Actor and Comedian Sinbad arrived on the comedy scene with a " hit'em in the face" style of comedy that has kept audiences laughing in the aisles for over the past two decades. Ranked by Comedy Central as one of the top 100 standup comedians of all time, Sinbad has built a loyal following by taking audiences' painful trials or embarassing tribulations of day-by-day life, throwing them back in their faces, and causing an uproar of comedic hysteria. Don't miss the laughs on February 15th!


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Board index » Question and Answer » Knife Recommendations Q&A
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BadBoy wrote:Tell me about the benefits of a cleaver over a chef knife for prep . . . who loves their cleaver and why do they us it instead of another selection.
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"The precepts of the law are these: to live honestly, to injure no one, and to give everyone his due." -- Justinian Code, A.D. 533.
The legal studies minor defines an area of study within the liberal arts. It includes courses that examine legal institutions from a humanistic or social science perspective.


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I just started this obsession this past Fall and the biggest problem I continue to have is consistent heat. For example, I've started 2 chimneys of lump and have trouble getting the temp to maintain-its a big spike, then quick drop. I initially started with 1 chimney, but have trouble getting the temp up to 225-250. I have played around with the air vents on the side and the chimney, but I do not feel I have any clue on what to do. I'd like to have some idea of what I'm doing instead of just winging it as I go along.
I would also like to know what the differences are (if any) of using lump or briquet's. Reading the posts, I thought the best thing to use was lump since it wouldn't give off any residue/odor and was a better heat. Is there a briquet that true bbq smokers use? And how much fuel should I expect to use smoking a butt? I seem to be going through more than a bag and refueling about every 45 minutes. I've seen posts where people say they can get their smoker to temp and leave it for much longer than that. I want to enjoy the process but I feel like I am constantly working on fuels issues and too stressed out about getting to, and maintaining, temp. that I'm not enjoying the process the way God intended:) Thanks for your help! My smoker is snowed in up to the handles, but I'm about ready to go dig it out and get the season started!!


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For registration details or more information please email: email@example.com
Aptis - Assess English Skills
In this section
What is Aptis?
Aptis efficiently and accurately assesses the English skills in your organisation for speaking, writing, reading and listening.
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Mike Pelfrey walked four batters and three of them scored. The fourth prolonged an inning and accounted for another run. Here's how bad it was: The D-Backs were 6-for-14 with runners in scoring position, but they still left 11 runners.
<img src="http://mets.lohudblogs.com/files/2008/04/images.jpeg" align="right" height="132″ width="133″ />
Tomorrow Johan Santana goes against Dan Haren, the guy I wanted the Mets to trade for last winter.
IN A NUTSHELL, Arizona 10, Mets 4.
If the all the runners the Mets left (four) would have scored they still would have lost.
Pitching coach Rick Peterson when approached to talk about Mike Pelfrey: "Ask (media relations director) Jay (Horwitz)." Peterson doesn't like to talk about his pitchers. He's the only uniformed Met who routinely won't comment about what he is responsible for.
Willie Randolph on Pelfrey: "He didn't pitch too well."
Pelfrey on Pelfrey: "I can't continue to have days like this."
3RD INNING: They have to be close to perfect to beat Webb and they haven't been. Some missed opportunities and Carlos Delgado's play at first. Arizona 2, Mets 1.
6TH INNING: Pelfrey's done for the day. So is Webb. Delgado's three-run homer puts Mets back in the game. Arizona 5, Mets 4.


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Mumford & Sons Sigh No More 3 CD Boxed Set
Oh how I love these scrappy UK lads. I get the idea that not only can they pluck a stringed instrument and harmonize in four parts.... but they can probably each throw a solid punch. Sounds great with Fleet Foxes and the Avett Brothers.


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SteveG wrote:Chris, you might want to check out the Sakai Takayuki Grand Cheff:http://www.chefknivestogo.com/satagrch24gy.html. It's got better steel than the Mac Pro IMO. They also have a Wa handled version: http://www.chefknivestogo.com/wagyuto.html.
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Tolleson's clutch knock lifts Blue Jays in ninth
Bullpen blows late lead before replacement infielder takes it back
ST. PETERSBURG -- Four batters into the ninth inning, Dan Johnson stood on third base at Tropicana Field and watched his old teammate, Grant Balfour, struggle.
Leading off the ninth in a 5-5 game, Johnson, a former member of the Rays, had walked -- as he did four times in the Blue Jays' 8-5 series-opening win against the Rays Friday night -- on four straight balls from Balfour.
Three batters later, Johnson was on third, Jose Reyes was on second -- and Steve Tolleson was about to drive them both in with a tiebreaking two-run single off Balfour, blooped down the right-field line.
"At the time when I got my walk, I think [Balfour] was still searching to try to find his release point," Johnson said. "I think I just came up at the right time at that point, where he was still kind of searching for it, so I think I lucked out by that. And then obviously we put a couple of good at-bats together, and then Tolly came through with that big hit."
Johnson was making his season debut, having flown into St. Petersburg from Triple-A Buffalo earlier that day, and he set the table for the Blue Jays four times -- the last one the most important. Tolleson wasn't even supposed to be in the game -- he was a seventh-inning replacement for Munenori Kawasaki, who exited with right hamstring tightness.
But it was still Tolleson and Johnson who ended up propelling the Jays to their second win in their last eight games. Toronto has scored 19 runs in its last three games after only scoring six runs in its previous five. The Rays have lost two in a row, and they gave up three runs in the ninth for the second straight night.
"I wasn't attacking guys, wasn't getting ahead," Balfour said. "The first guy, I walked. You don't want to walk the leadoff guy. For me, it was embarrassing."
And costly. By getting to Balfour for three runs -- Jose Bautista added an RBI single two batters after Tolleson -- the Blue Jays bailed out their own bullpen.
In the seventh inning, Dustin McGowan had coughed up a three-run lead in a span of three batters. McGowan entered the game with two outs, nobody on and his team in front, 5-2. But he walked Evan Longoria and James Loney, and Sean Rodriguez crushed a slider deep into the left-field seats to tie the game.
McGowan wasted the effort of quick-working Mark Buehrle, who got the better of methodical Chris Archer over five innings.
The veteran left-hander -- who pitches at the fastest pace in the Major Leagues, compared to Archer, baseball's third-slowest pitcher -- allowed nine hits in five innings, but held the Rays to just two runs. That wasn't much solace to Buehrle, though.
"I'm going five innings. It's not really called for," Buehrle said. "I'm upset. ... You put your bullpen in a tough situation, so I need to go deeper in a game to give us a chance to win."
In the first inning, Buehrle found himself in a bases-loaded, no-out jam after giving up three straight singles to start the game. But he got out of it after only a Longoria sacrifice fly when Loney bounced into an inning-ending double play.
Buehrle gave up the second run in the fourth after three straight two-out hits, the last an RBI single down the left-field line by Ben Zobrist. Five of the Rays' hits against Buehrle came with two outs.
"I'd get two quick outs, it seemed like, a lot," Buehrle said. "And then I got guys on, walked guys. I mean, I'm frustrated with myself.
"I got two quick outs, got ahead in the count, started nitpicking, got deep into counts, seven-pitch at-bats. [I] look up and after four innings, I have 85 pitches. That's not acceptable."
Still, Toronto looked to be in good shape, managing five runs on six hits off of Archer in his five innings. The Blue Jays looked lost against Archer in the first two frames, striking out five times against the young right-hander, but they touched up Archer for three runs in the third and two more in the fourth.
The Blue Jays pounded out four hits in the third, and when they loaded the bases, they got three runs where the Rays had only gotten one -- on singles by Kawasaki and Melky Cabrera and a sac fly by Bautista. In the fourth, they added two more runs on Reyes' two-out, two-run single.
That lead disappeared on Rodriguez's home run, but Toronto got it back for good when Johnson crossed the plate in St. Petersburg for the first time since his game-tying, pinch-hit home run with two outs and two strikes in the bottom of the ninth inning of Game 162 in 2011 -- when the Rays dramatically beat the Yankees in extra innings to make the playoffs on the season's final day.
Actually, since Johnson was 0-for-0 with four walks on Friday, that home run is still his last official at-bat at The Trop. And even though his walk in the ninth wasn't exactly heroics, it set the stage for Tolleson's.
"You need that. That was a big hit for him," Blue Jays manager John Gibbons said of Tolleson's flare. "He struggled against right-handers and hadn't had a chance to face a lot, so that was a huge hit."
David Adler is an associate reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.


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Product Code: 1732
Release Date: 1970
This was the perfect outfit for the fashion-conscious sister of Barbie® doll! The hot pink dress featured a big, graphic daisy print fabric for the collar, long sleeves, attached belt, and matching daisy print or hot pink tricot knee socks. Yellow Taiwan flats completed the set.
All images and descriptions courtesy of Collector Books, publisher of "Barbie Fashion: Volume 1" and "Barbie Fashion: Volume 2" by Sarah Sink Eames


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With the MultiTunes tweak, I don't understand why people can't just duplicate the iTunes music folder which holds all of the library data, across all their computers, so the User can sync between them all, under the one library, as they alternate between their computers. (Although if you're syncing music automatically each time you plug in your device, what I said above won't work since you won't have an identical library across all computers unless you use dropbox or something to host your songs)
I didn't know people still bought music lol,,,
MultiTunes is no doubt the best tweak here. It's something I've been waiting for, since the first time I plugged my iPhone into a friends computer, and immediately lost all my data. That was a horrific experience, and I don't care one bit for online piracy laws. This has nothing to do with piracy. This kind of sharing is normal human behaviour.
Screen Swipe Sounds should be replaced by iSounds on this list, which adds sounds to basically everything else besides changing pages, and its free. Judging from the screenshots, majority of the sounds included with Screen Swipe Sounds are just filler which no one would use
I find it funny, though, that this site is so against piracy (they don't even allow you to say the names of warez sites), yet they happily post a step by step on how to get Siri working on a non-4S device (for the record I have no problem with either, and often try before I buy, at the very least). You are literally tricking Apple's servers into thinking that the device you are using is something else. If you weren't using Apple's resources in your jacked Siri query that would be one thing, but that just isn't the case. I don't care how you define it, it is just as bad as borrowing that CD and ripping the tracks for your own use. You are using a service that is exclusive for a device that you didn't pay for. End of story.


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By Varietal
I have been all over the world for my job in the Air Force and one of my faviorite places to visit was Thailand. I love the spicy ,sweet and sour flavors of green curry.
The Vintage Van Gogh Articini Burger was so good I didn't think it could be topped. I was wrong.
I've fallen in love with pomegranates and decided to incorporate them into a burger.
I wanted to create a healthy, low-fat, low-calorie, whole-wheat family meal for the grill with a southwest flair!
We wanted something tasty, healthy, easy and different. The first time I made them I was just grabbing things in the kitchen that I thought would go well together to wake up all five tastes.
Why roast a turkey? Here's Thanksgiving dinner on a bun, available and easy to make all year 'round.
This is a healthful and tasty alternative to a beef burger. It is very satisfying and leaves you with a full stomach but not a heavy feeling.
A burger that is tasty, healthy and fun to create for a gathering of family or friends.


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Here is another query that has come into the MadAboutGenealogy website. The query is in blue and my answer is in black.
My great grandfather was a lock keeper at Ivinghoe Locks at the early part of the 19th Century. By chance I found a photo of him on ancestry but the image is too small to read the description underneath, I have since spent hours trawling websites to see if I could find any more photos but no luck. Do you have details of lockeepers or can you recognise where this photo may have come from?
kind regards Liz
Hi Liz
Like you I couldn't make out the inscription under the rather splendid photograph of Jabez Windmill so I searched the public Ancestry Trees online for Jabez and checked out the ones that had the small photo logo next to them. The logo is a picture of a small camera and indicates that pictures are attached.
The second tree I checked was one entered by Sally Channing and she had the same photo as the one you sent me the link to, but this time it was crystal clear.
The inscription reads
The lock keeper: John Windmill with his daughter Ella at Ivinghoe Lock on Sunday 15 May 1904 on which they attended the anniversary of Ledburn Baptist Chapel, near Mentmore.
The photo was originally submitted by Christopher Windmill and has been copied onto several other trees. I did click on Christopher's name to see if I could find out what else he had submitted, but it came up as profile unavailable so perhaps his Ancestry subs has lapsed.
Lots of lovely clues in that inscription; the date and place of the photograph, it's John Windmill not Jabez Windmill, he has a daughter Ella and they were non-conformists.
Hope this helps,


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Home » Western Saddles & Tack » Western Tack » Western Breast Straps » Weaver Leather Texas Star Tapered Breast Collar
Weaver Leather Texas Star Tapered Breast Collar
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Weaver - American Made Quality!Attention-getting Texas star concho highlights the center of this breast collar for a unique look you'll love. Constructed from premium English bridle leather, this breast collar features nickel brass spots and nickel plated zinc die cast Texas star conchos with an 18 karat gold plated star for a striking look. Features a center ring with leather backer, an adjustable center strap and a tie down dee. Width tapers from 1 1/4" to 1". Non-rust stainless steel hardware (except snap is solid brass).
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Voice for Equality: Laura Ricketts
Postedon Oct 21, 2010 at 01:30 pm
Laura Ricketts is co-owner of the Chicago Cubs and CEO of Ecotravel.com. Ricketts is also a board member of Lambda Legal and the Housing Opportunities for Women organization.
Ricketts' ownership stake in the Cubs is uniquely noteworthy because it makes her the first openly gay owner of a major-league sports franchise.
Former first lady Laura Bush urged her husband not to make the freedom to marry an issue in 2004
Postedon Apr 30, 2010 at 07:00 am
Former first lady Laura Bush has written in her memoir, "Spoken From the Heart," that she urged her husband not to make marriage equality a significant issue in the 2004 election because they had - and still have- "a number of close friends who are gay or whose children are gay." Bush writes, "[A]t that moment I could never have imagined what path this issue would take and where it would lead."
Karl Rove and his Gay Dad
Postedon Mar 18, 2010 at 03:03 pm
It's not exactly startling to see that Karl Rove has denied he was aware his own father was gay, even as he guided the GOP into anti-gay wedge politics in the last decade (the Christianists, he coolly calculated, had potentially way more votes for the GOP than gays and their families). But it is important to note that it is untrue that he had no idea his dad was gay or that he was unaware it was the reason for his parents' divorce.
Bush advisor and outspoken opponent of freedom to marry is granted second divorce
Postedon Dec 30, 2009 at 11:13 am
December 29, 2009
Karl Rove's second divorce is making headlines because he has been an outspoken opponent of the freedom to marry. Rove is considered the architect behind using marriage equality as a wedge issue during the 2004 presidential election, which helped President Bush defeat John Kerry. [Link]
Evan Wolfson: Bill Clinton can be a Very Important Voice in Explaining Why He Changed His Mind
Postedon Aug 20, 2009 at 08:16 am
August 20, 2009
Bill Clinton's remarks on DADT and DOMA in Pittsburgh last week have drawn criticism from several LGBT leaders. Evan Wolfson, however, points out that "We don't need to look backward... it would be better if he talked about why he's moved ahead." [Link]
Gay-Baiting '08
Postedon Aug 06, 2008 at 10:07 am
August 5, 2008
Starting in 2000 the invocation of gay rights issues – and the biggest "threat" of all, marriage equality – has been the stuff not just of political humor but of political advertising and cable news punditry as well. Today, nearly every prominent political news analyst, left, right, or center, seems to agree that gay-bashing as an overt political strategy is either dying or already dead. [Link]
California Dreaming: Homophobia Will Not Determine this Election
Postedon Jul 02, 2008 at 06:48 pm
July 1, 2008
Joe Solmonese, President of the Human Rights Campaign, explains why the California Supreme Court's decision to uphold the freedom to marry will not affect the 2008 election. (Link)
Republicans, beware of marriage politics
Postedon Jul 01, 2008 at 05:33 pm
July 1, 2008
Patrick Sammon, president of Log Cabin Republicans, exposes the lies about marriage as a wedge issue in the 2004 election, and warns in regards to marriage, "Republicans who try exploiting the issue for political gain this November will fail." (Link)
Gay marriage redux
Postedon Jun 25, 2008 at 10:34 am
June 24, 2008
Mark Mellman shows that not only were theories of anti-marriage amendments affecting the 2004 presidential race baseless and wrong, but also such theories are again wrong about the California anti-marriage initiative this year affecting the 2008 presidential election. (Link)
OPINION: No one's benefit in MI
Postedon Jul 09, 2007 at 04:19 pm
July 9, 2007
When Michigan voters passed the discriminator ban on gay and lesbian couples' marriages in 2004, they made a mistake. When Michigan Attorney General Mike Cox used his position to further his personal beliefs and ban same-sex benefits as well, he made the voters' mistake much worse. Now, the University is in a tough spot as it must mitigate these realities. Its attempts to deal with the dumb law and Cox's dumber interpretations are flawed. The only solution is that Michigan voters must abolish the nonsensical "gay marriage" ban. [link]