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Status cataplecticus is a rare manifestation of narcolepsy with cataplexy episodes recurring for hours or days, without a refractory period, in the absence of emotional triggers. This case highlights a narcoleptic patient who developed status cataplecticus after abrupt withdrawal of venlafaxine.
Wang J; Greenberg H. Status cataplecticus precipitated by abrupt withdrawal of venlafaxine. J Clin Sleep Med 2013;9(7):715-716.
Cataplexy is a symptom of narcolepsy triggered by strong emotion that causes sudden muscle atonia with preserved consciousness. It may represent intrusion of REM sleep phenomena into wakefulness.1 A refractory period of up to several hours typically follows a cataplexy attack.2 Persistent cataplexy, known as status cataplecticus, is a rare, often misdiagnosed manifestation of cataplexy. Failure to recognize this condition can lead to unnecessary diagnostic testing that delays appropriate therapy.2
Tricyclic antidepressants (TCAs), selective serotonin reup-take inhibitors (SSRIs), and serotonin-norepinephrine reuptake inhibitors (SNRIs) prevent cataplexy.3 Enhancement of noradrenergic and serotonergic activity may reduce cataplexy by inhibiting "REM-on" neurons in the lateral dorsal tegmentum (LDT) and pedunculopontine tegmentum (PPT).3 The precipitous decrease in noradrenergic and serotonergic tone occurring upon abrupt discontinuation of therapy may elicit status cataplecticus, presumably by disinhibition of "REM-on" neurons.3 Interestingly, discontinuation of sodium oxybate, another anti-cataplexy medication that may exert its effect via GABAB receptors, has not been associated with status cataplecticus.4
A 76-year-old female was evaluated 20 years ago for hyper-somnolence and "irresistible sleep attacks" that began during adolescence. She experienced sleep paralysis but denied hypnogogic or hypnopompic hallucinations. Strong emotion such as anger, happiness, or excitement often precipitated slurring of speech, flattening of facial expression, and leg weakness. She cannot recall whether cataplexy appeared concurrently or after onset of somnolence. Medical history was significant for hypertension treated with lisinopril. Polysomnography demonstrated a normal apnea-hypopnea index. Multiple sleep latency testing revealed a mean sleep onset latency of 3 minutes with 3 sleep-onset REM periods. She was HLA-DQB1*0602 positive. CSF hypocretin levels were not obtained. The diagnosis of narcolepsy with cataplexy was made at age 56, nearly 40 years after symptom onset.
Initial treatment consisted of imipramine and methylpheni-date. Persistent cataplexy and hypersomnolence prompted a change to sodium oxybate and modafinil with almost complete resolution of symptoms. Sodium oxybate (9 grams nightly) was continued for seven years until she reported somnambulism and nocturnal sleep eating with multiple falls. As these were likely NREM parasomnias associated with sodium oxybate, anti-cataplexy therapy was changed to venlafaxine ER 75 mg/day. Cataplexy persisted, but further increase in venlafaxine was precluded by worsening hypertension, an adverse effect of venlafaxine. Fluoxetine 20 mg was suggested. The following day, she developed gastroenteritis; while she continued venlafaxine, she reported emesis shortly after taking medication. The next day, emotional upset triggered cataplexy, consisting of slurred speech and weakness in all extremities; this was witnessed by her family. Unlike her usual cataplexy episodes which rapidly resolve, she experienced continuous cataplectic attacks over the next 4 h, despite absence of further emotional triggers. She maintained consciousness throughout but recalled vivid hallucinations. Fluoxetine was ineffective; upon resuming venlafaxine, cataplexy resolved within several hours. Neurologic examination was not performed during status cataplecticus but was normal the following day after resolution of cataplexy.
Our patient experienced status cataplecticus within 48 hours of abrupt withdrawal of venlafaxine, due to diminished absorption from gastroenteritis. The resultant rapid decrease in noradrenergic and serotonergic tone may have precipitated status cataplecticus.3 Status cataplecticus has been reported in narcoleptic patients after abrupt withdrawal of clomipramine, a serotonergic reuptake inhibitor that augments adrenergic tone via its metabolite, desmethylimipramine.3 Protracted episodes of cataplexy have also been reported after gradual withdrawal of TCAs and SSRIs, peaking 40 to 60 days after discontinuation.3 Status cataplecticus may also occur with administration of prazosin, an α-adrenergic antagonist.5
While the neurophysiologic basis of cataplexy remains unclear, decreased hypocretinergic activity with reduced noradrenergic tone, possibly from decreased activity of locus coeruleus neurons, may contribute to decreased motoneuron excitation during cataplexy. Dysfunction of other neurotransmitters, including dopaminergic systems, may also contribute to cataplexy.6
Status cataplecticus is a rare complication in narcolepsy resulting from abrupt discontinuation of noradrenergic and serotonergic medications. Behavioral management restricting social interaction to minimize cataplexy triggers, and limiting ambulation, may be helpful during status cataplecticus. Anti-cataplexy medications, with individualized risk-benefit analysis regarding adverse effects, such as parasomnias and fluid retention from sodium oxybate, hypertension from venlafaxine, and anticholinergic effects from clomipramine are necessary. First line therapy for cataplexy is sodium oxybate; however in this case, risk of falls from somnambulism in an elderly woman outweighed benefits. Venlafaxine ER was reinitiated and gradually increased to 150 mg/day with resolution of cataplexy; escalation of antihypertensive therapy controlled blood pressure.
This was not an industry supported study. The authors have indicated no financial conflicts of interest.
Broughton R, Valley V, Aguirre M, et al., authors. Excessive daytime sleepiness and the pathophysiology of narcolepsy-cataplexy: a laboratory perspective. Sleep. 1986;9:205–15. [PubMed]
Calabro RS, Savica R, Lagana A, et al., authors. Status cataplecticus misdiagnosed as recurrent syncope. Neurol Sci. 2007;28:336–38. [PubMed]
Ristanovic RK, Liang H, Hornfeldt CS, Lai C, authors. Exacerbation of cataplexy following gradual withdrawal of antidepressants: manifestation of probable protracted rebound cataplexy. Sleep Med. 2009;10:416–21. [PubMed]
US Xyrem Multicenter Study Group. Sodium oxybate demonstrates long-term efficacy for the treatment of cataplexy in patients with narcolepsy. Sleep Med. 2004;5:119–23. [PubMed]
Aldrich MS, Rogers AE, authors. Exacerbation of human cataplexy by prazosin. Sleep. 1989;12:254–56. [PubMed]
Peever J, author. Control of trigeminal motoneuron behavior and masseter muscle tone during REM sleep, REM sleep behavior disorder and cataplexy/narcolepsy. Arch Ital Biol. 2011;149:454–66. [PubMed]


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VIA's QuadCore: Nano Gets Biggerby Anand Lal Shimpi on 5/12/2011 3:01 AM EST
36 Comments
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todlerix - Thursday, May 12, 2011 - linkneat Reply
vol7ron - Thursday, May 12, 2011 - linkAnand, nice review. If there is no power gating and TDP is locked, did VIA give any indication as to why they implemented clock-gating and did not just maximize the performance to begin with?
I suspect it may be to reduce heat or wear-leveling, but it'd be nice to hear their reasoning. Still, even if the clock was maxed, I'm not sure it would generate that much heat, or have any long-term impact on the shelf-life.
Thoughts? Reply
MrSpadge - Thursday, May 12, 2011 - linkHere TDP probably means "thermal design power" rather than "typical power draw". It's the maximum a system with such a CPU has to deal with, not what the CPU will typically use.
And their reasoning is probably very simple: clock gating is easier than power gating.
MrS Reply
Wesleyrpg - Thursday, May 12, 2011 - linkwould be pretty cool to give VIA another go, but i haven't even seen a board to utilises the Dual Core Nano, yet alone the quad core!
VIA, please get these out to the public!!!! Reply
beginner99 - Thursday, May 12, 2011 - linkWhere are the chips? Nano has been around forever but I have never seen a single product here actually using it. Is it limited to USA? Or Asia?
I think A dual or quad Nano could be nice for a self-made NAS or HTPC. Reply
ppeterka - Thursday, May 12, 2011 - linkEven though this is not a Nano CPU (AFAIK, but I might be wrong on that), ASRock has two VIA boards, an ITX and a "slightly bigger than ITX but lot more features" microATX one: http://www.asrock.com/mb/overview.asp?Model=PV530
They're also rather cheap, going for less than ~$60 even here in Hungary... They might be good budget x86 media-HTPC projects. Especially the one with a suitable PCIe slot to accept a video card with digital output.... Reply
DanNeely - Thursday, May 12, 2011 - linkSearch for miniITX, nanoITX, and picoITX boards. You'll find lots of companies selling vias hardware. Reply
Spazweasel - Thursday, May 12, 2011 - linkEmbedded computing, data acquisition and industrial control. Reply
ProDigit - Friday, May 13, 2011 - linkvery little boards because competition generally is better power wise, or performance wise, or feat wise, or price wise, or all 4 together! Reply
Griswold - Thursday, May 12, 2011 - linkIts kinda bizare seeing these illuminated, windowed and overclocked boxes in a productive environment for designing different CPUs. :0 Reply
wordsworm - Thursday, May 12, 2011 - linkreally, would make a good partnership. Reply
tipoo - Thursday, May 12, 2011 - linkAgreed, although I'm not sure VIA's x86 license would carry over in a buyout. In any case, Nvidia is going to be doing some neat things with ARM, with what looks like a cell-like chip in which a high performance ARM core (or more) controls many CUDA cores, that sounds like it has potential. Reply
rahvin - Thursday, May 12, 2011 - linkIf the Via x86 License was transferable then nVidia would have bought them a year ago when they made all the waves about x86 licenses. All indications are that if Via changes hands again the x86 license goes away. There are also indications that when it changes hands last time Intel added some conditions about how Via could use the license at least that's my opinion. IMO Via's limited themselves to certain market segments that at the time of the last transfer Intel wasn't interested in. This may simply be economics but I also think it's possible that they are contractually limited to those areas from conditions Intel extracted during the last transfer of the Centuar group.
Anyway, my main point is that it's pretty common knowledge that if Centaur trades hands again the x86 license is gone making the division worth nothing on the open market. If Via/S3 can't make the business work they will simply evaporate unless they can get the government to force Intel to make the sale possible. Reply
gayannr - Thursday, May 12, 2011 - linkI wonder what AMD is using for their simulations ? i7 ? :) Reply
qwertymac93 - Thursday, May 12, 2011 - linknah, probably magny cours. Reply
Prosthetic Head - Thursday, May 12, 2011 - linkAMD will almost certainly be using their own chips. I am a computational chemist and regularly run large simulations on HPC facilities. Most of these use AMD chips. For example the HECToR machine built using Cray XE6 units uses 44,544 cores worth of 12-core AMD Opteron 2.1GHz Magny Cours processors.
AMD do very well in the HPC space. Reply
Prosthetic Head - Thursday, May 12, 2011 - linkOh and the spec of the machines next upgrade has just been confirmed:
"The solution supplied will be a 30 cabinet system utilising the next generation AMD Interlagos processor and Cray's Gemini interconnect. The machine will have a projected theoretical peak of 820TF and as such represents a greater than two-fold increase in capability over the current Phase 2b system." Reply
tipoo - Thursday, May 12, 2011 - linkI'll reserve my judgement, but right now I can't see this being competitive at all. Its basically the dual core variant with two dual-core chips glued together, and only minor architectural tweaks. Add in the required graphics that it doesn't have, and its power consumption will be much higher than Brazos as the article says. I can't see a segment it would be better in, its kind of the awkward middle child between processors for ultramobiles and processors for netbooks, it doesn't really fit the bill of either.
Interesting chart, are Atoms finally more powerful than a Pentium 4 2.66GHz now? AMD's even more so. Not bad. Reply
L. - Monday, May 23, 2011 - linkAnd that's without considering that Brazos is going to be 32nm sometime soon -- poor VIA they never could make anything useful could they ? Reply
Soulkeeper - Thursday, May 12, 2011 - linkOne of the better articles i've read in awhile.
Nice to see a small company like via rolling up their sleeves and making cpu's "24 at a time" to compete with the monster intel.
the extra 2 cores + beefed up padlock is very interesting
i'd be interested in seeing how that competes with i7 Reply
tipoo - Thursday, May 12, 2011 - link"i'd be interested in seeing how that competes with i7 "
It won't. The Nano competed with the Atom, the dual core one with dual core Atom and Brazos, this one probably aims a bit higher at ultraportable laptops. It's definitely not a high end i7 competitor. Maybe a ULV competitor, but its wattage ratings aren't even that good, hence why I was confused about its purpose in my comment above yours. Reply
simple_inhibition - Thursday, May 12, 2011 - linkim thinking that soulkeeper was talking about AES encryption, something that VIA cpu's have always excelled and even lead at in comparison to AMD and Intel. with Intel rocking AES-NI instructions on their latest and greatest, it would be an interesting comparison between the 800lb gorilla and the 24 chips at a time VIA Reply
swaaye - Wednesday, May 18, 2011 - linkVIA has had AES hardware in their CPUs for generations, probably because the companies that use VIA CPUs require it for their applications. It's not something that's particularly useful to have in the CPU in many situations though. Reply
GullLars - Wednesday, May 25, 2011 - linkI'm also interrested in seing how the AES of VIA stacks up against i7s. It could make for a good budget crypto-fileserver on Gbit network when paired with an older cheap RAID controller (like PERC, Adaptec 5xxx, or HighPoint X3xx/x4xx). Reply
L. - Monday, May 23, 2011 - linkIt's not going to compete, by the time it's out and gets a tiny wee bit of market adoption it'll be slaughtered by 32nm products from both Intel and AMD , and on the lower side by ARM designs .. maybe 6 months earlier it could have been useful .
At least it show there's competition, always a good thing. Reply
ZL1Corvette - Thursday, May 12, 2011 - linkI wonder if you bumped into any other hardware site people while you were there? Reply
Veerappan - Friday, May 13, 2011 - linkI'm thinking so. One of those pictures was very similar to one I saw on TR yesterday afternoon (guy in front of wall-sized die shot). You can also hear a few voices in the background of that first video explaining things. Reply
ICBM - Thursday, May 12, 2011 - linkI have used several single core nano itx boards here at the office. Performance has been good for single core. I have been waiting since the dual core announcement for those to show up, but still nothing.
When will VIA have boards with the dual-core chip? What about board availability with quad-core? Reply
krumme - Thursday, May 12, 2011 - linkAt its very best for many years. The world has not come to an end yet :)
Its so damn impressive VIA can survive this game. Reply
ICBM - Thursday, May 12, 2011 - linkFor how long though. :( Reply
xxtypersxx - Friday, May 13, 2011 - linkGreat article Anand, nice to see Via still churning out product. I work supply chain in the industry and the shots of their facility remind me of several other smaller component shops that seem so heavily concentrated in Phoenix.
I do want to point out however that while Via is a huge underdog, they certainly aren't making chips 24 pieces at a time on a normal basis. This is their initial silicon testing (as the guide said in the video) so they are just utilizing their internal low rate capacity to crank out a few hundred test units. The vast majority of their output undoubtedly happens in Taiwan or China and likely gets sold directly to board oems over there to be integrated before ever reaching the US or other target markets. Reply
xxtypersxx - Friday, May 13, 2011 - link*Point out to the posters above that is, Anand surely knows this. Reply
ProDigit - Friday, May 13, 2011 - linkNot mentioning their quadcore CPU consumes more than double what an Atom N550 consumes with GPU together!
For real, if netbooks existed with 2 atom N550 processors worked in them, they would not only overpower this via chip(being faster) , but also underpower it (using less power)!
This via chip is everything but efficient!
Still, I'd say it's a nice try, though I can't find any space in the market for this chip! Reply
softdrinkviking - Saturday, May 14, 2011 - linkas much as i would like to see them succeed, it just doesn't seem like nano has made a big enough dent to keep going like this.
there must be someone, or someones, evaluating the profitability of this project and trying to decide if it's all worth it, right?
and how long before intel pulls out the rug from under them with the x86 license? that's not set in stone, if i remember correctly.
maybe they would do better to compete with ARM design or something? Reply
ChuckDriver - Tuesday, May 17, 2011 - linkWhen I saw the very impressive array of bare motherboards and cased, water cooled, & overclocked computers running Intel processors in Centaur's simulation lab, I was reminded of the old line about Airbus' fleet of Super Guppies: "every Airbus is delivered on the wings of a Boeing."
There is a similar story about Seymour Cray. When told that Apple had recently bought a Cray to design the next Macintosh, he responded by saying that he bought a Macintosh to design the next Cray.
http://research.microsoft.com/en-us/um/people/gbel... Reply
crwl8 - Thursday, May 19, 2011 - linkI suggest VIA to go additional way, performance way. Is it so dificult to increase voltage and multiplier to get around 3GHz and go to compete with Athlon X2,X3,X4 (if not with performance, then with price/performance)?
Approach of two segments (ulv and budget desktop) ,with minimum effort, could have double success Reply

subset: commoncrawl


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I am shocked no one else noticed this...
At the start of the film, it is clearly established that Luna Lovegood was in Shell Cottage, where she was when the last film left off. The group apparated to there following their collective escape from the Bellatrix LeStrange.
Luna is at Hogwarts upon Harry's arrival, and acts as though she has been there all year. Furthermore, she is in the Gryffindor common room, despite being a Ravenclaw.
Had Luna left Shell Cottage and enrolled herself at Hogwarts, she would surely have been turned in to the Death Eaters. I therefore conclude that there is a continuity error in this film.
Response -- She was never in the Gryffindor common room, she was in the Room of Requirement with the other students who were escaping the Death Eater regime at Hogwarts. She did not "enroll herself to Hogwarts", she got in through the passageway between the Room of Requirement and Aberforth Dumbledore's pub, the Hogs Head.


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The HOW-TO book for reading aloud effectively to young children
Help Me Get Ready To Read
The Practical Guide For Reading Aloud To Children
During Their First Five Years
by Susan Marx & Barbara Kasok
Reading aloud effectively starting in infancy and through the preschool years helps young children acquire the essential early literacy concepts and skills they need to get ready to learn to read. Help Me Get Ready To Read has an easy-to-use format that includes:
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Positive Parenting Praise! that shows how to help children feel comfortable, confident, and competent.


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Judge James Fleetwood
CJCC Chairman
525 N. Main
Wichita, KS 67203
p. 316.660.5611
Justice Reinvestment Initiative - April 2013
Pretrial Release Screen - March 2013
The Bail Bondsman - Effective Criminal Justice Partners - July 2012
Best Practices in Pretrial Services - June 2012
This presentation was created by the Pretrial Justice
Institute, which helps local justice systems establish pretrial practices.
Institute for Law and Policy Planning Report - December 2003
"This report is driven by the county's request for a
population and system study, as well as the insights and values of the leaders
in all the justice system agencies who provided data and extensive interviews
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Wichita State University - Update of the Sedgwick County Adult Detention
Facility - October 2010
"The research questions posed herein involve a look at the
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text:
HOUSTON — Oilfield services company Baker Hughes Inc. says the number of rigs actively exploring for oil and natural gas in the U.S. decreased by 11 this week to 1,748.
The Houston-based company said Friday in its weekly report that 1,390 rigs were exploring for oil and 353 for gas. Five were listed as miscellaneous. A year ago there were 1,959 active rigs.
Of the major oil- and gas-producing states, West Virginia and Wyoming each gained three, California gained two and Colorado and New Mexico gained one each.
Texas lost 11 rigs, Oklahoma lost five and Louisiana and North Dakota each lost three. Alaska, Arkansas and Pennsylvania were unchanged.


text:
MAYOR-ELECT Tim Munro has lost his chance of becoming Portland's first citizen after a new vote was taken at a meeting last night.
Town councillors were asked if they had any other nominations for the role of mayor and Cllr Munro, Cllr Rod Wild and Cllr Rob Hughes were all proposed. But it was Cllr Hughes who got the most votes.
His deputy will be Cllr Wild.
The mayor-making ceremony was due to take place last week but it was cancelled amid chaotic scenes.
Residents protested Cllr Munro's nomination outside last week's meeting. Mayor Les Ames told the council he would be deferring the meeting due to a 'serious difference of opinion,' regarding the nomination.
There were similar protests before last evening's meeting with people standing outside the venue in Fortuneswell holding placards reading 'No Tim Munro for Mayor'.
Cllr Munro became unpopular after he led the island precept increase which provoked a major revolt.
Before the meeting, protestor Sue Lees from the Voice of Portland residents' group said: "We don't want him as mayor."
Les Ames stepped down from the office of mayor and received a standing ovation and cheers in tribute to all his good work.
Cllr Ames said the island was very important to him and was a wonderful place to live.
Speaking after the meeting, Mr Ames added that today would be his last day as a councillor as he would be retiring.
Cllr Hughes thanked the councillors and members of the public and said his chosen charities would be the NCI Coastwatch and Dorset Air Ambulance.
After the meeting, Cllr Munro said he was not upset and said he had no issue with the decision.
He said that the whole situation had got a lot of people involved in the town council that perhaps otherwise wouldn't have been there.


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Federal Judge: Citizens Need Not Ask Permission to Exercise 2nd Amendment Rights
The New American
Wednesday, March 7, 2012
A federal judge struck down a Maryland law requiring individuals to prove that they have "good and substantial reason" for seeking a handgun carry permit from the state.
"A citizen may not be required to offer a 'good and substantial reason' why he should be permitted to exercise his rights," wrote U.S. District Judge Benson Everett Legg. "The right's existence is all the reason he needs."
The suit was brought by Navy veteran Raymond Woollard, who lives on a farm in rural Baltimore County. On December 24, 2002, Woollard's son-in-law, Kris Lee Abbott, on a drug-induced high broke into Woollard's house during a family gathering in search of his wife's car keys so he could go buy more drugs. Woollard momentarily stopped Abbott by aiming a shotgun at him, but Abbott wrested the gun away from him, only to be halted again by Woollard's son, who also had a gun. Woollard and his son then kept Abbott at bay until the police arrived two-and-a-half hours later.
Abbott was convicted of first degree burglary and put on probation. He was later incarcerated for violating his probation.
Woollard, who now knew that he could not count on the police to come to his aid in an emergency, applied for a handgun carry permit in 2003. The permit was granted, as was Woollard's request to renew it three years later, just after Abbott was released from prison. However, when Woollard attempted to renew his permit again in 2009, his request was denied by the Maryland state police on the basis that he had not demonstrated to their satisfaction that he was in danger. His appeals were denied on the same basis.
The Rest…HERE


text:
Following in the footsteps of the pioneering flights of the 1920s, 15 vintage aircraft built in the early 1900s take to the air for a truly unique rally across the Americas. The VintageAirRally starts on the 1st March 2018 from Ushuaia, Argentina and finishes on the 14th April in Florida, USA. The Rally connects some of the most beautiful and evocative points, combining the challenge of flying these magnificent planes with the element of competition which was equally prevalent in those early days.
The Rally begins from the world's southernmost airport, heading north to Florida, journey's end.
A rally such as this has never been done before in South America – and follows on from the successful 2016 VintageAirRally Crete2Cape.
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With 15 years cleaning experience we specialise in very high cleaning standards Carpet Cleaning using a top of the range machine We provide all cleaning services inc homes, holiday accommodation, offices, exterior cleaning services and power washing. We offer a top quality service with very competent people at the best prices possible.
Ninja Cleaners Devon
Here at Ninja Cleaners Devon its our mission to provide affordable, professional and competitive cleaning service. Your time is important to us, so Ninja Cleaners Devon are ready to give you a free quote on the phone or by email instead of taking the time for visiting you! If you need regular daily, weekly, fortnightly or monthly domestic cleaning, or one-off services like end of tenancy or after builders cleaning, you've certainly came to the right place.
Vapor CleanCertificate of Excellence 2015
Vapor Clean provide domestic and commercial cleaning services, we combine our great system (Vapor Cleaning) and methods with the right staff to create professional, experienced and knowledgeable experts, who can adapt and combine the system with the correct traditional methods to get the job done to the highest standard possible in the greenest way possible, all whilst ensuring the work is being carried out efficiently and safely and being less labour intensive means always remaining cost effective for the customer.
Plymouth Cleaning
Plymouth Cleaning are a family founded and family run company. We pride ourselves on being friendly and approachable while offering professional cleaning services for domestic and commercial premises. All of our comprehensive services are carried out to the highest standards in a discreet and efficient way, for domestic, commercial, offices, business, contract cleaning and one off cleans or spring cleans, every aspect of cleaning is undertaken in a professional way using the best cleaning materials and equipment. At Plymouth Cleaning we are constantly developing and updating our services to help deliver quality, affordable and progressive cleaning to our clients. We are a professional and experienced cleaning company who will treat your home and office with the love and careful attention it deserves. Whether it's a quick freshen up or a thorough deep clean or anything in between, Plymouth Cleaning do it all. We have established a loyal customer base of letting and estate agents, landlords, businesses and individual residents, which we strive to keep and grow. That's why quality is important for us.
First 4 Repairs Ltd
First 4 Repairs are a planned, preventative and reactive maintenance and refurbishment company delivering repairs with a can do attitude striving to deliver ''a service you can trust'' throughout the South West
HUNDUCK cleaning service
It is our pleasure to be of service to you the customer with all of your cleaning and ironing needs. We're cleaning Plymouth and surrounding areas! For a free quote contact with us please and our customer service will be happy to help you. Cleaning: all supplies and equipment are provided and our hourly rate £10. Ironing: collecting and delivering included and our rate £3 / kg
Penny's Domestic Cleaning
We are a family run domestic cleaning company with cleaners in Plymouth, East Cornwall, the South Hams and surrounding areas. Our aim is to provide our clients with unbeatable service, always going the extra mile to get the job done! We offer a flexible, reliable, and comprehensive domestic cleaning service to suit your individual requirements. Our professionally trained staff are equipped to deliver the highest standards of service, and are covered by our public liability insurance for your peace of mind. We offer a whole range of cleaning services: - Domestic cleaning (w/o materials, w/ materials, w/ green-clean materials) - Commercial cleaning (w/o materials, w/ materials, w/ green-clean materials) - Holiday lets change-over cleans / management - End of tenancy cleans - One off cleans - Oven cleans - Carpet cleaning - Window cleaning - Ironing - Pressure washing - Steam cleaning - Mattress and upholstery cleaning
Hall's Cleaning
Hall's Cleaning is a professional local family run Commercial and Domestic Cleaning Business with high standards in our work, our motto is " We don't cut corners...we clean them", we think this explains our work ethic perfectly. We work in Plymouth and all of it's surrounding towns and areas including the Royal William Yard. We clean homes, offices, small shops and industrial units, holiday lets, communal areas and student accommodation. There is no contract period required, and we'll even do 'one-off 'cleans for you i.e. moving house or a spring clean.
Welcome to 'Devon's Greenest Cleaning' company established over 15 years ago in Totnes South Devon and now providing a wide service to Plymouth, Exeter and surrounding areas as well. We offer professional eco-friendy cleaning services accross a wide range of sectors. Including Domestic, Commercial, Holiday Lettings & Holiday Homes.
Classic Clean 4 u
House Cleaning -
mop and brush
Cleaning services as discussed by the customer
Mikes Bulgaria Limited.
cleaning of empty properties regular cleaning of furnished properties Catering division; wedding buffets, event catering for Shows/Theatrical events
PROcleanswCertificate of Excellence 2015
PROcleansw is a new cleaning business operating in and around The South West. We are a small independent company. We thrive on having an ethical business focused on our customers and our team. At PROcleansw we have many years of experience between us in the cleaning industry and as a team we've covered every aspect of commercial and domestic cleaning and housekeeping. We are able to provide an eco friendly cleaning service that is specifically designed for your situation. We deal with Domestic homes, Commercial contracts, 2nd homes, Holiday lets, Emergency, Insurance cleans, after build cleans, Landlords pre/post tenancy cleans, jet washing. We know our service is second to none and that you will be more than happy to stay with us, because of our ethics and standards. Our team motto is "we don't cut corners, we clean them" and this is so true, we want our customers to be proud of their homes as we are proud of our reputation. We all understand how to work efficiently without compromising your private life. www.procleansw.uk 01803391039 07746705646
End of tenancy Cleans Carpet Cleaning Oven cleaning Office contract One off spring clean
Torbay F.M.
Welcome to Torbay Facilities Management. We provide a range of property, pool and spa maintenance solutions for both commercial and domestic customers throughout The South West. For great customer service and quality as standard contact us today to discuss your requirements.
Harry J
I provide handyman services and also as a general helper within the Torbay area.
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High spec contract commercial and domestic cleaning
OCD Cleaning Services
We offer any form or services related to the commercial, industrial or residential cleaning sector 24 hours a day From window cleaning to carpet cleaning Pressure washing to gutter cleaning Blocked drains to sparkle cleans Whatever the work, it will be a clean sweep
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Helene Hewitt
I am self employed. I teach both able and disabled people to ride horses. I judge dressage at local unaffiliated events. I judge and course build at local unaffiliated showjumping events. I offer all the usual equine services. I also clean properties to a high standard. Offices, homes holiday lets. I clean weekly,fortnightly or one offs.
Estuary Cleaning Services
Regular Domestic Cleaning in the Exeter and East Devon area
Jurassic Coast Helping HandsCertificate of Excellence 2015
The concept of Jurassic Coast Helping Hands is based on total attention to detail and the personal touch. We offer a 5* domestic cleaning service as well as assistance with any other tasks such as shopping, laundry, dog walking and more.... We offer a friendly, caring, personal and excellent service to all our clients. Our pleasant, experienced and trustworthy employees are available to undertake all of your household chores and can do almost anything! Whether it's a weekly clean, making the beds, ironing, or even taking the dog for a walk, we will try to provide a service that fits around your busy schedule to ensure you can relax and have some quality leisure time.
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Unity Living & Mobility Supplies Ltd
We provide home care services from nursing care to domestic cleaning. Shopping services and even form filling for those who struggle. We also supply living aids and carry a large range of incontinence pads. We provide retail and rental services for mobility equipment, free delivery within 10 mile radius! We accept card payments over the phone or in our showroom.
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H&E Cleaning Solutions provide a wide range of Cleaning Services which includes: Household and Domestic Cleaning, Office Cleaning, Retail Cleaning, Public Facility Cleaning (Public Toilets, Village Halls etc.) End of Tenancy Cleaning, Exterior Window Cleaning (sub contractor) Deep Cleaning and Showroom Cleaning. If you are looking for a different type of clean that isn't mentioned in the list above then give us a call and we will try our best to provide a solution for you.
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Cleaners on Bark
We have 12226 Cleaners actively using Bark.com.
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Within hours, sometimes minutes, they'll contact you on Bark.
Professionals value their reputation on Bark and strive to do a great job for customers they find on our platform.


text:
Dempster struggles, offense quiet in loss to Jays
Right-hander surrenders three homers, with bullpen allowing two more
BOSTON -- April flowers have brought May showers for the suddenly cold Red Sox.
After his team was beat up by the Blue Jays on Sunday en route to a 12-4 defeat, its eighth loss in the last 10 games, manager John Farrell thinks the Sox have used up all of their luck.
"As much as we cashed in in the month of April, it may be cliché, but things are evening out," Farrell said.
The Red Sox, who held at least a share of the top record in the Majors as recently as May 8, have dropped three straight series and fallen to 22-16 on the season.
Being swept by the Rangers, who entered Sunday tied for the best record in the Majors, seemed like a blip on the radar. Losing the next two series -- to a Toronto team with a struggling pitching staff and free-swinging offense and a Minnesota team that strikes out fewer batters than anyone in the Majors -- might seem more like a radar-jammer.
"Just keep grinding -- that's all you can do," said catcher Jarrod Saltalamacchia.
The key in this series was supposed to be keeping the ball down in the strike zone. The Blue Jays, who lead the Majors in homers, with 51, also rank in the bottom third in batting average, at .237.
Between starters Jon Lester and Clay Buchholz, the Red Sox didn't allow one ball to leave the yard.
Between Junichi Tazawa giving up the eventual game-winning shot on Saturday, Sunday starter Ryan Dempster allowing three homers and relievers Andrew Miller and Clayton Mortensen each serving one up later in the game, the Blue Jays hit six homers in the last 10 innings of the series.
Dempster, who hadn't allowed more than one home run in a game all season, posted his worst start in a Red Sox uniform. He lasted just five innings, allowing six runs on seven hits and a walk.
"I've just got to do a better job," Dempster said. "They were two sliders that just hung up in the zone. I didn't have the slider I normally have. I didn't have it today. It's unfortunate."
Because he is one of the softer throwers in the Majors, Dempster's location and pitch mix become that much more important. His first miss came in the third inning, when Jose Bautista took an 89-mph inside fastball and jacked it over everything in left field.
Then, in the fourth, Emilio Bonifacio, who had just one homer over his previous two Major League seasons, launched a hanging slider into the right-field bullpen. Shane Victorino's leaping effort was just short, and he flopped straight to the ground after hitting the wall. He remained in the game after a visit from the training staff but was removed in the seventh inning due to stiffness, according to Farrell.
Dempster's final mistake came in the fifth inning, when he uncharacteristically left a splitter, his signature pitch, high in the zone. Edwin Encarnacion replied with a booming swing that put the Blue Jays on top, 6-1.
It should be easy to forget one bad start from Dempster, who is striking out more batters than ever -- fanning 11.44 per nine innings -- and has a 3.75 ERA.
"I've been feeling really good this year," he said. "Even today, my arm feels good, my body feels good. I just didn't execute pitches. It's nice as you get older to continue to feel good. That's an important thing, but at the same time, you can feel as good as you want or as bad as you want, you've got to execute pitches. Hopefully, I can continue to do that on a consistent basis."
At the plate it was more of the same for an offense that's been outscored, 62-33, over the past 10 games.
Toronto starter Chad Jenkins, who entered Sunday having pitched just once this year, a five-inning start for Double-A New Hampshire, held the Red Sox to two runs over five innings.
"Honestly, I threw fastball/changeup the entire game," Jenkins said. "We stuck with those two pitches, and there wasn't really a whole lot of adjustment."
The Red Sox are hitting .163 with runners in scoring position over the last 10 games, a span in which they've left 86 on base.
"I think we have a number of guys dealing with some frustration right now," Farrell said. "There's no question about it. The key for us is to maintain our preparation and our work routine. Those are the key things that we can control."
Half of the offense on Sunday came from Mike Napoli, who hit his seventh home run of the season, and Pedro Ciriaco, who came off the bench to play first base -- the seventh position he's played in his Major League career -- and contribute his first homer of the year.
Monday will be the Red Sox's last off-day until June 3 and it comes just in time, as they'll look to regroup before playing 14 of their next 20 games on the road.
Jason Mastrodonato is a reporter for MLB.com. Follow him on Twitter @jmastrodonato. This story was not subject to the approval of Major League Baseball or its clubs.


text:
Print this recipe
Grilled Shrimp With Lemon-Garlic Butter
Print this recipe
20 comments:
- Anonymous7/11/12, 4:30 PM
Thank you for suffering the heat for your fan base :) Definitely going to try this next time we have shrimp! I also soak my bamboo skewers, I do the whole pack at the same time and then put them in a zip-lock bag and put them in the freezer. They are ready whenever I need them - I just need to find them in the freezer!ReplyDeleteReplies
Grrrreat idea. Thank you so much for passing on such great tip.Delete
hope you don't mind me saying this.........damn this looks good!!ReplyDelete
Since it's only 102 here today I shall brave the elements once I find the shrimp!!Replies
I don't mind you saying.Delete
Can't wait to try this shrimp dish...it sounds scrump-dilly-ump! I love the fact that it is so fast and there aren't very many dishes to wash!!ReplyDeleteReplies
I'm with you!Delete
The husband is the Grill Master in our household. The wife, just trying to impress him from time to time ;) He adores shrimps. (She is hypersensitive to shrimps) Anyhow, I would love to really try this recipe (despite the allergy,) I will enjoy his newlyfound faith in my grilling skills once I nail this.ReplyDelete
Myfudo here...We normally would not put shameless plug back to us, but we just launched our new site and we would love for you to be a part of it.
We are moving to a new domain http://www.yumgoggle.com, (previously myfudo.com) this has been a project we have been working on for almost a year now. Unique and interesting bloggers like you will make the Yumgoggle gallery more fun and exciting.
We'd love you to join the latest virtual shindig that is all about food photography, food in general, recipes, and culinary trends. We'd be proud to have your work as part of our growing collection to continue to have a larger reach and further inspire all fellow food lovers out there! Please sign up and check us out (it's free) www.yumgoggle.com/gallery . We look forward to seeing your wonderful pictures, as always.
p.s. We are hosting a Kitchen Aid Mixer Giveaway to celebrate our new Yumgoggle site, coming soon in our launch post, we hope you'll participate =)
Hi Janet, a question. You write that you heat up the pot at 450 degrees. According to Le Creuset, the handles will hold only about 370 degrees out. Do you have any problems with the knob?ReplyDelete
Since you rave so from the pots, I've now bought two ...
Greetings from Germany
Janet, this is perfect for the weather here(monsoon)...gonna surprise my hubby this Saturday...love ur detailed post...have a great day.ReplyDeleteReplies
Best of luck to you. Thank you so much for posting your comment. Where is your part of the world?Delete
- Amanda7/26/12, 7:56 PM
Quick question- what brand are the pans you use? We're looking for a similar set so I was curious!ReplyDelete
I use Al-clad pans. I love them. My skillet is Mauviel Copper, which is just amazing. They are super expensive. I received them as a gift from a very generous woman that I gave some cooking classes to. I'm so lucky.Delete
I just stumbled across your blog today and I've already found so many recipes that I want to try! Thank you!ReplyDeleteReplies
I hope you come back for more. Thank you for nice comment.Delete
- Anonymous8/2/12, 6:50 PM
Is there anyway to go about this recipe without using a grill. It looks absolutely wonderful but due to the weather it would be much easier to try it differently. Any suggestions?ReplyDeleteReplies
Sure. Just saute the shrimp in a little oil in a skillet. Remove from the heat and add the garlic butter. Good luck.Delete
OMG!!! Started the no knead bread process last night... only a few more hours till it hits the oven! In the mean time I see this jaw dropping pic of the shrimp!!! On my way to the store to get all the things to make this too with the bread! I'll let you know how it all turns out.I'm so excited!!!ReplyDelete
Thank you Janet!
I just discovered your blog. I love it! Your recipes are my favorite! Thank you!!ReplyDeleteReplies
Thank you for the kind comment. I'm so glad you found me!!Delete
That. Was. Awesome. Thanks!ReplyDelete


text:
While m_reader.Read
If Not m_reader("cname") = "" Then
End If
End While
For Each item As String In arryname
i hve the above code in which i am adding the fields 2 arrayfor retriving the values of each field i will need to execute the for loop twicehow can i retive values of both array items using a single loop
Since you seem to be using a very basic array for both items, you could do this.
Dim item As Integer
For item As Integer = 0 To arryname.Length - 1
And to cover any rare situations where the array lengths may end up different
Dim item As Integer
For item As Integer = 0 To arryname.Length - 1
If item < arryname.Length Then
End If
If item < arrymail.Length Then
End If
refercing elow but i get error in .add , error at from
tried using Dim dictionary As New Dictionary(Of String, String)
Dim m_readersc As SqlDataReader = cmdsc1.ExecuteReader() While m_readersc.Read If Not m_readersc("cname") = "" Then dictionary.Add(m_readersc("cid"), m_readersc("cname")) End If End While
errror index out of range
On which line.... I assume it is referring to your m_readsc("cid") or m_readsc("cname") as your current code isn't trying to read from the Dictionary at this point.
the abovr errr was due to a blank field. now i get thee belowerror
Value of type 'String' cannot be converted to 'System.Collections.Generic.Dictionary(Of String, String)'.
For Each value As Dictionary(Of String, String) In dictionary Dim id As String = value("cid") Dim description As String = value("cname") Next
Use your debugger, it should make it obvious which of those arrays have an index out of range and it won't be the dictionary.


text:
Problem Description and Possible Solution
Some vehicles may exhibit one or more of the following: Spark knock complaints when the vehicle is under load, various single cylinder misfire, and surge in 4th gear (around 45 mph). Our technicians tell us that rerouting the coil and spark plug wires to minimize induction effects will commonly correct this condition. If wires must cross during the reroute procedure, they must cross at a 90 degree angle.
Problem Data
RepairPal Verified
Average mileage: 129,000 (129,000–129,000)
9 people reported this problem


text:
Assessment |
Biopsychology |
Comparative |
Cognitive |
Developmental |
Language |
Individual differences |
Personality |
Philosophy |
Social |
Methods | Statistics | Clinical | Educational | Industrial | Professional items | World psychology |
Personality: Self concept · Personality testing · Theories · Mind-body problem
Tolerance for ambiguity or ambiguity toleranceis the ability to perceive ambiguity in information and behavior in a neutral and open way.
Ambiguity tolerance is an important issue in personality development and education. In psychology and in management, levels of tolerance of ambiguity are correlated with creativity,[1] risk aversion, psychological resilience, lifestyle,[2] orientation towards diversity (cross-cultural communication, intercultural competence), and leadership style.[3]
Wilkinson's Modes of Leadership is largely based on ambiguity tolerance. Mode one leaders have the least tolerance to ambiguity with mode four leaders enjoying and preferring to work in ambiguous situations. In part this is due to what Wilkinson calls 'emotional resilience'.
The converse, ambiguity intolerance,[4][5] which was introduced in The Authoritarian Personality in 1950,[6] was defined in 1975 as a "tendency to perceive or interpret information marked by vague, incomplete, fragmented, multiple, probable, unstructured, uncertain, inconsistent, contrary, contradictory, or unclear meanings as actual or potential sources of psychological discomfort or threat."
See alsoEdit
References Edit
- ↑ Kirton, M.J. Adaption-Innovation In the Context of Diversity and Change. Oxford: Routledge, 2004.
- ↑ Apter & Desselles (2001) in Motivational Styles in Everyday Life: A Guide to Reversal Theory. Washington: APA Books, 2001.
- ↑ Wilkinson, D. The Ambiguity Advantage: What great leaders are great at. London: Palgrave Macmillan, 2006.
- ↑ Robert W. Norton. "Measurement of Ambiguity Tolerance." Journal of Personality Assessment, Vol. 39, No. 6, pp. 607-619 (1975). Abstract: DOI:10.1207/s15327752jpa3906_11 .
- ↑ A. Furnham and T. Ribchester. "Tolerance of Ambiguity: A review of the concept, its measurement and applications." Current Psychology, Vol. 14, No. 3, pp. 179-199 (1995).
- ↑ The Authoritarian Personality, Studies in Prejudice Series, Volume 1. Co-authors: Theodor Adorno, Else Frenkel-Brunswik, Daniel Levinson and Nevitt Sanford. New York: Harper & Row, 1950. W. W. Norton & Company paperback reprint edition, 1993: ISBN 0-393-31112-0.
|This page uses Creative Commons Licensed content from Wikipedia (view authors).


text:
Please enter your postcode or local town into the box below to find your nearest branch.
Online Exclusive products are not stocked in your chosen branch. They are ordered in for you and will normally be available within .
Direct from Supplier products are not stocked in your chosen branch.They will be ordered for you from the supplier, who willdeliver them directly to your business address.
You will need to provide credit card details for these items at checkout.


text:
370 Express — By Capt. Stuart Reininger
— September 2000
A Kinder, Gentler Fishkiller
|The Stamas 370 gets the game without the pain.
One of the advantages of owning a top-of-the-line, head-turning fishboat is the dockside attention factor. Let's face it, you're not going to get much admiration offshore when you and your boat–and everybody else out there–are busy tracking the game. It's when you're backing into the slip that you collect those admiring glances. There's something about a fish dock at the end of the day–boats shaping up to maneuver into their slips amidst the haze of exhaust and deep rumble of diesels–that draws the attention of anyone within sight or sound.
Well, if you're at the helm of the Stamas 370 Express, you can forget about all that–the sound and fury, anyway. Sure, you'll still get the admiration factor. The 370 Express, with her sharp entry and sweeping, slightly reversed sheer that breaks gently into a raised cockpit coaming, is one of the sweetest-looking fishboats out there. But she doesn't make enough noise to draw attention to herself; you'll have to do that by hanging a grander over the side. And unless you have a load of three-day-old fish, you can skip the olfactory attraction–no exhaust fumes, ever.
That's because this Stamas can be equipped (for $5,200) with the Eco Sound EPS 1000 underwater exhaust system. Sound familiar? Yes, you read about it in these pages ("The Sweet Sound of Success," September 1999). After gaining acceptance as an aftermarket installation on a number of cruising, performance, and fishing boats, Eco Sound was adopted as standard equipment on Boston Whaler's 34-foot Destiny and as an option on Formula's new 41PC.
So, how does a boat manufactured by a family-owned company with almost 50 years of experience go through her paces with a system that supposedly quiets exhaust, eliminates fumes, and even improves back-down performance?
Well, for starters, the last boat I was on that accelerated this smoothly had a stepped hull. Despite the fact that the 370 doesn't, my test boat planed with no stern squat and little bow rise; I never lost sight of the horizon. As for fumes and smoke, none. When I firewalled the twin 420-hp Yanmar 6LTY2-STYs, I glanced back, and there, about 50 yards astern, were the exhaust bubbles and fumes.
But our Stamas really came into her own in reverse. You know what happens when you back down hard: You usually enter a cloud of smoke accompanied by the impact of the transom hitting a wall of water. If you've left the transom door open or the boat has drains without check valves or flappers, you get a cockpit washdown, too. Not here. No dramatics, no wall of water, and no fumes. Just good steering response without having to work the props. In fact, our boat practically planed in reverse.
This article originally appeared in the January 2003 issue of Power & Motoryacht magazine.


text:
SAINTS forward Anthony Laffranchi is to leave Super League and return to Australia at the end of the season, the player has announced.
The 34-year-old prop, who has made 66 appearances for Saints since joining them from Gold Coast Titans ahead of the 2012 season, intends to hang up his boots and take up a development role at his old club.
Laffranchi, who won five caps for Australia and made four State of Origin appearances for New South Wales, represented Italy in the 2013 World Cup but missed three months of the 2014 season after undergoing surgery for a career-threatening arm injury.
"I'd made up my mind pretty much to go home at the beginning of the season and, when the surgery was suggested, it was in my mind to get it done, get some rehab and then go back with some function in my arm,"
Laffranchi said: "I had to think post rugby league and the quality of life with my three kids.
"I've enjoyed my time here and wish I would have come over a bit earlier. It is a great club, I love the culture and I have been blessed to have been here.
"I will be sad to leave but will be starting a new chapter at the Titans."
Laffranchi is a month into his comeback and hoping to end his career on a high by helping Saints to Grand-Final glory at Old Trafford in October.
"I thought my season was over," he said. "This is my new year in a way.
I've been back a month now and I feel good.
"It's good to be coming back into some big games at the end of the year.
Now we have to kick on.
"We want to finish top and put a little silverware there. It will be disappointing if it comes to the last week and we get knocked off. We have been there most of the year and it will be disappointing if we let it go."


text:
THIS SUBLEASE dated this 19th day of August, 2017BETWEEN:
____________________(the "Sublandlord")
____________________(the "Subtenant")
IN CONSIDERATION OF the Sublandlord subletting and the Subtenant renting the Subleased Premises, both parties agree to keep, perform and fulfill the promises, conditions and agreements below:
IN WITNESS WHEREOF the Sublandlord and the Subtenant have duly affixed their signatures under hand and seal on this 19th day of August, 2017.
A Commercial Sublease Agreement is used when a business tenant sublets the rental space to a subtenant without breaking his or her current lease with the landlord or property manager.
The subtenant pays rent to the tenant who signed the original lease and only rents the property (either a portion, or the entire rental space) until the end of the lease term.
A Commercial Sublease is the agreement made between the subtenant and sublandlord (the original tenant) and contains information about both parties, the original lease, landlord consent, financial responsibilities (such as damage deposit, utilities, and insurance), and any other additional terms of the lease deemed relevant by the parties.
Landlord: The landlord is the person who owns or manages the property, offered the property for rent, and signed a lease with the tenant. The landlord must give permission to the tenant to sublease the space.
Tenant/Sublandlord: The tenant is the party who originally rented the commercial space from the landlord. Once the tenant sublets the space, he or she becomes the sublandlord. A tenant must still report to the landlord and he or she is still held to the terms of the original lease.
The sublandlord is responsible for the subtenant and any damages that are caused by the subtenant.
Subtenant: The subtenant is the person who rents the commercial space from the original tenant, also called the sublandlord. The subtenant will make rent payments and report any lease or property issues to the sublandlord. The subtenant's lease relationship is with the tenant/sublandlord and not the landlord or the landlord's property manager.
Before acquiring a subtenant, the tenant should refer to the master lease to see if subleasing arrangements are allowed. If so, the landlord will still need to be notified and written permission from the landlord may be required.
If subleasing was not allowed or not mentioned in the original lease, the tenant will need to obtain a Landlord's Consent to Sublease to make sure that no lease terms are breached and that the landlord is informed of the tenant's wish to sublet the space.
You may need a Commercial Sublease if:
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