text:
Simple Text Chat Box Learn how to use a simple idea to make text chat web application
#31 Guest_KHURRAM SHAHZAD*
Posted 07 July 2010 - 03:07 AM
But i want little changes in recieving of mesages update ... here you used request to server after every 3-seconds using AJAX ... is it possible that server it self send update to clients/users when any update occurs without making request to server from client('chatbox.js' in this example).
if possible then plz atleast give mean idea / mechanism.
Posted 10 July 2010 - 06:08 PM
the Server can not request or connect to the client's javascript, javascript works independently on the client's machines whilst php works on the server side.
that's why we request the server and get the information back to the client through http request.
maybe something like XML Socket (I might be wrong) can do this but unfortunately it's not available for javascript
Posted 14 July 2010 - 11:16 PM
Unfortunately I wasnt able to get it working. It just gave me a JS error on the bottom of my browser.
Not too worried about it though, just letting you know.
Thanks anyway.
Posted 15 July 2010 - 11:11 AM
What kind of error,
can you please provide the error message you got and the code you're testing.
Thanks to let me know
Posted 15 July 2010 - 07:16 PM
ahmad_511, on 15 July 2010 - 10:11 AM, said:
What kind of error,
can you please provide the error message you got and the code you're testing.
Thanks to let me know
Hey, I just deleted everything and tried all over again. It's working just fine now.
Posted 16 July 2010 - 06:18 AM
Blueorb, on 15 July 2010 - 06:16 PM, said:
ahmad_511, on 15 July 2010 - 10:11 AM, said:
What kind of error,
can you please provide the error message you got and the code you're testing.
Thanks to let me know
Hey, I just deleted everything and tried all over again. It's working just fine now.
Hi Ahmad,
may i request can you please help with how to put time against a user, that is the time the user logs in and the time the user leaves the room. thanks you. or just record time-in and time-out in file.
Posted 16 July 2010 - 09:27 AM
@AjusJudy, please follow these steps:
1- open the users.php file in your favorite text editor.
2- add the following function before or after the function saveUsers() :
function logEvent($event,$showAsMessage){ $logs=fopen("logs.txt","a+"); fputs($logs,"<".date("Y-m-d H:i:s")."> ".$event."\n"); fclose($logs); if($showAsMessage){ $room=fopen("room_".$_POST['room'].".txt","a+"); fputs($room,time()."<!@!>BOT<!@!><!@!>".$event." @ ".date("Y-m-d H.i.s")."\n"); fclose($room); } }
this function accepts two arguments:
$event: is the string you want to log
$showAsMessage: is a boolean controls whether you want to make the legged event appears for everybody as a message on the chat box or not, (it will be saved in the log.txt file in both ways)
3- search for the sign in confirmation:
echo "signin";
and add call the logEvent() fucntion directly after it, you'll have something like this:
echo "signin"; logEvent($user." join the '".$_POST['room']."' room",true); exit();
4- do the same for the sign out confirmation with a little change to the event message:
search this time for "signout" and call the logEvent():
echo "signout"; logEvent($user." exit the '".$_POST['room']."' room",true); exit();
5- create a new text file "logs.txt" in the same directory where you have the php scripts and make sure it's writable.
BTW AjusJudy, I didn't forget your previous request about the database version of the chatbox, but I'm really having none stable days and barely can focus on my job.
#38 Guest_chris*
Posted 18 September 2010 - 05:14 AM
#39 Guest_chris*
Posted 18 September 2010 - 05:24 AM
#40 Guest_Anony-Mouse*
Posted 28 October 2010 - 06:39 AM
#41 Guest_Anony-Mouse*
Posted 28 October 2010 - 06:43 AM
#42 Guest_Anony-Mouse*
Posted 28 October 2010 - 06:47 AM
someone plz help me i downloaded the files but i cant sign in to the chat.
#43 Guest_David*
Posted 28 October 2010 - 09:09 AM
Posted 28 October 2010 - 03:46 PM
first of, I would like to thank you for the comments, and sorry for any inconvenience.
second of, I've uploaded the chatbox files with all suggested updates to my website so you can try it in action(it works fine for me as is but I updated the ajax.js to the one I already use)
Note for Admins/Mods: please remove the link above if you see it's not appropriate to link to external site
and here is the files chat.zip (35.4K)
Number of downloads: 695
if the live one works for you, that means there might be something with your code.
anyways, try the attached files.
emotion codes:
3i,angr,cry,dip,lol,sad,sarc,sweet (ex :sad: or :lol:)
Tested on IE7+IE8 quirk and standard mods, FF 4.0b2, Chrome 7.0.517.8, Safari 5.0.2(7533.18.5)
if nothing helps, please add more information about error message may occurred or a link to a live version where we can see what's happening there.
#45 Guest_bridge*
Posted 23 February 2011 - 05:37 AM
This post has been edited by JackOfAllTrades: 23 February 2011 - 06:08 AM


text:
Books are just one of those things that are so versatile. They can work for a vintage-themed wedding, a whimsical wedding or just as a little added touch. We pulled together some of our favorite ways that people have incoporated books into their wedding. From simple props to deconstructed pages, check out the links below to find DIY directions and more ideas.
L to R: book centerpiece, book photo props, book heart garland, book bouquet, book decor, book guestbook

subset: commoncrawl


text:
Study to Assess the Safety and Tolerability of Intravenous Carbamazepine in Adults With Epilepsy
- Full Text View
- Tabular View
- Study Results
- Disclaimer
- How to Read a Study Record
|Drug: Intravenous Carbamazepine (IV CBZ)
|Phase 3
|Study Type:
|Study Design:
|Intervention Model: Single Group Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
|Official Title:
|Open-Label Study to Assess the Safety and Tolerability of Intravenous Carbamazepine as Short-Term Replacement of Oral Carbamazepine in Adult Patients With Epilepsy
- Adverse Events [ Time Frame: Baseline to after last iv dose on day 4 ]
|Study Start Date:
|June 2010
|Primary Completion Date:
|January 2013 (Final data collection date for primary outcome measure)
|Assigned Interventions
|Experimental: Intravenous Carbamazepine (IV CBZ)
Drug: Intravenous Carbamazepine (IV CBZ)
10 mg/mL of IV CBZ dissolved in 250 mg/mL of Captisol® (sulfobutylether-beta-cyclodextrin) dosed at 70% of the patient's daily maintenance dose of oral CBZ administered after suitable dilution with D5W by IV infusion every 6 hours.
Detailed Description:
This was a phase III, multicenter, open-label study designed to assess the safety and tolerability of intravenously administered CBZ in adult patients with epilepsy. This study included a 28 day Lead-in Period, a Confinement Period (up to 7 days and 6 nights) and a 28 day Follow-up Period.
Patients began confinement on Day -1 of the trial, continuing to take their oral CBZ as prescribed by the investigator. On the morning of Day 0, Day 4, and Day 17, patients began the 24hr urine collection for evaluation of urinary biomarkers. All patients temporarily discontinued their prescribed oral CBZ and begin IV CBZ administration on the morning of Day 1, continuing administrations every 6 hours (Q6h) through the morning of Day 4.
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- The patient or legal representative must be able to read, understand, sign and date the IRB approved Informed Consent Form and HIPAA Authorization prior to study participation.
- The patient is a man or a non-pregnant woman who is at least 18 years of age.
If a woman:
- Patient is either not of childbearing potential, defined as postmenopausal for at least 1 year or surgically sterile (bilateral tubal ligation, bilateral oophorectomay or hysterectomy), or if childbearing potential, must comply with a method of birth control acceptable to the investigator during the study, for at least 28 days prior to Day 1 and for 28 days following completion of the study.
- Patient is not breastfeeding.
- Patient of childbearing potential must have a negative serum pregnancy test at Day -28 and a negative urine pregnancy test or serum pregnancy test at Day -1.
The patient is diagnosed with any of the approved epilepsy indications for CBZ:
- Partial seizures with complex symptomatology (psychomotor, temporal lobe)
- Generalised tonic clonic seizures (GTCS) (grand mal): myoclonic, clonic, tonic, tonic-clonic, atonic
- Mixed seizure patterns that include the above, or other partial or generalised seizures (except absence seizures - please see exclusion point number 12)
- The patient is receiving a stable dose of oral CBZ (tablet or capsule formulation) of 1200 mg/day to 2000 mg/day, for a minimum of 14 days prior to Day -28.
- The patient is receiving a constant dose of all other concomitant medications used for chronic conditions, (including OTC medications and herbal supplements) for a minimum of 28 days prior to Day 1.
- The patient is not expected to have any change in his/her baseline AED treatment during the treatment period.
- The patient is able to comply with maintaining an accurate Seizure and antiepileptic drug diary.
- The patient is able to comply with all study procedures including complying with protocol determined dosing intervals, confinement at the investigative site for up to 6 nights and 7 days, and agrees to participate in the entire study.
Exclusion Criteria:
- The patient has a known hypersensitivity to CBZ, Captisol, or to any of the tricyclic compounds, such as amitriptyline, trimipramine, imipramine; oxacarbazepine, phenytoin, or their analogues or metabolites.
- The patient has a history of previous bone marrow depression.
- The patient has a history of intolerance to IV administration of medication.
- The patient is pregnant or lactating.
- The patient is being treated with a monoamine oxidase (MAO) inhibitor.
- The patient is using oral, intramuscular, or any other hormone delivery method as their primary form of birth control.
- The patient has an ECG with corrected QT interval by Fridericia's correction formula (QTcF) greater than 450 msec at Screening or Day -1.
- The patient has a screening ALT, AST or bilirubin >=3 times the upper limit of normal.
- The patient has an estimated ClCR (based of Cockcroft-Gault) of <50 ml/min.
- The patient has had a clinically significant illness/infection or has had any surgical procedure within 30 days prior to Screening.
- The patient has a significant history of cardiac, renal, neurologic (other than epilepsy), psychiatric, oncologic, endocrinologic, metabolic, or hepatic disease, which would adversely affect their participation in this study.
- The patient is receiving oral CBZ for absence seizures.
- The patient has had an episode of status epilepticus within 4 weeks of Screening.
- The patient has a history of severe or serious adverse reactions to CBZ (for example, aplastic anemia, agranulocytosis, SJS.
- The patient has taken or used any investigational drug or device in the 30 days prior to Screening.
- The patient has previously been administered IV CBZ in a previous clinical trial (for example OV-1015).
- The patient has a urine toxicology screen positive for phencyclidine, benzodiazepines (unless due to the patient's concomitant AEDs), cannabinoids, cocaine, amphetamines, opiates, barbiturates (unless due to the patient's concomitant AEDs), or alcohol at Screening or Day -1.
- The patient has had a diagnosis of drug or alcohol abuse within the past year prior to Screening.
- The patient has had significant blood loss (>500 mL) or donation within 14 days of Screening.
- The patient has a history of poor oral CBZ compliance.
- The patient is participating in a weight loss or nicotine cessation program.
- The patient has a history of increased intraocular pressure or is on medication for glaucoma.
- The patient is considered by the investigator to be an unsuitable candidate for the study, which may include an increase in the frequency, severity and duration of seizures during the Pre-Treatment Period (Days -28-0).
- The patient has previously participated in this study.
- The patient is a member of the site personnel or their immediate families.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01128959
Show 29 Study Locations
|Study Director:
|Email contact via H. Lundbeck A/S
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
|Responsible Party:
|Lundbeck LLC
|ClinicalTrials.gov Identifier:
|NCT01128959 History of Changes
|Other Study ID Numbers:
|Study First Received:
|May 21, 2010
|Results First Received:
|October 10, 2016
|Last Updated:
|December 12, 2016
Keywords provided by Lundbeck LLC:
Intravenous Carbamazepine
Oral Carbamazepine
Additional relevant MeSH terms:
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Antimanic Agents
Tranquilizing Agents
Central Nervous System Depressants
Physiological Effects of Drugs
Psychotropic Drugs
Analgesics, Non-Narcotic
Sensory System Agents
Peripheral Nervous System Agents
Cytochrome P-450 CYP3A Inducers
Cytochrome P-450 Enzyme Inducers
Molecular Mechanisms of Pharmacological Action
ClinicalTrials.gov processed this record on August 23, 2017


text:
A diverse group of livestock organizations, The Cattle Identification Group, sent a letter this week to Agriculture Secretary Tom Vilsack asking for an extension of the public-comment period on USDA's proposed framework for animal-disease traceability. Following is the text of the letter.
Dear Mr. Secretary:
The Cattle Identification Group (CIDG) was formed a couple of years ago to provide input into the U.S. Department of Agriculture's (USDA) development of an Animal Disease Traceability (ADT) framework and plan for the identification and traceability of cattle moving interstate. The participating members of the CIDG represent all classes of cattle and segments of the cattle industry with membership spanning the length and breadth of this country.
As development of USDA's ADT program proceeded over time, the CIDG as well as its individual industry organizations have been active participants in the various meetings and discussions that USDA has held around the country throughout the development of the program. In that regard, we very much appreciate USDA's efforts to develop the ADT program with transparency, openness and an evident desire to have the cattle industry's input on a regulatory program that is sure to have a huge impact on every livestock operation in the United States
The proposed ADT rule (Docket No. APHIS-2009-0091) was published in the Federal Register August 11 with a 90-day comment period, ending November 9. Within weeks of the proposed ADT rule, the CIDG met to begin our discussions on the various aspects of the proposal and what, if any, remaining concerns and/or questions we have respective to the ADT program as established in the proposed rule. It was obvious from the very beginning of our initial discussion on the ADT proposed rule that there remains a great deal of work yet to be done by the CIDG and our individual organizations in assessing all the numerous repercussions, connotations, and consequences of the many different aspects of the proposed rule. It also looks likely that we will need to do some additional work on assessing the cost to industry stakeholders in complying with the ADT rule, particularly once all cattle are required to be identified. In addition, numerous questions are being raised about various elements of the proposal that will need clarification by USDA staff in order for us to responsibly inform and respond to the membership of our organizations in the short time that remains of the current comment period.
While the CIDG and our individual organizations are feverishly scheduling additional meetings to work through the proposed rule, it has become very apparent to us all that a proposed rule of this importance and magnitude, with all it potential impacts and disruption of the cattle industry, will require that cattle industry stakeholders be given additional time to consider and develop the industry's response to the proposed ADT rule. Also, our respective organizations are finding it difficult to schedule meetings right now with our leadership, committees and members to get their guidance on outstanding issues with the proposed rule as we enter later than usual summer harvest in some parts of the country, fall harvest in the Corn Belt, the fall run of feeder cattle moving to market, the increased marketing of cattle due to severe drought in parts of the Southwest and now, recent flooding conditions along the East Coast.
At a time of economic uncertainty, high unemployment, and limited funds for new programs such as ADT, it is an absolute necessity that any new regulations imposed on the cattle industry be as cost effective, efficient, workable and no-nonsense as is humanly possible and that all the time necessary to achieve that result is made available to the industry. Many improvements have been made by APHIS in the last two years regarding this challenging issue. We would not want an inadequate length of the proposed rule comment period to derail all of our collective efforts and negate any positive progression of cattle identification for animal health purposes. Thus, as the industries' most affected by this proposed rule, we respectfully request that the current comment period be extended an additional 60 days to give affected stakeholders the needed time to thoroughly review, discuss and develop in-depth comments on this extremely consequential regulatory proposal.
For questions or in responding to the CIDG's request for an extension of comments, please contact Ms. Nancy Robinson, CIDG Coordinator; Livestock Marketing Assn., 10510 NW Ambassador Drive, Kansas City, MO 64153; phone 800-821-2048; e-mail: firstname.lastname@example.com.
The Cattle ID Group
American Angus Association
Dairy Farmers of America
Livestock Marketing Association
National Cattlemen's Beef Association
National Livestock Producers Association
National Farmers Union
Red Angus Association of America
Southeastern Livestock Network
Texas Cattle Feeders Association
Texas and Southwestern Cattle Raisers Association
U.S. Cattlemen's Association
cc: APHIS/VS Deputy Administrator Dr. John Clifford; House Committee on Agriculture Chairman Frank Lucas; House Committee on Agriculture Ranking Member Collin Peterson; Senate Agriculture, Nutrition and Forestry Committee Chairwoman Debbie Stabenow; Senate Agriculture, Nutrition and Forestry Committee Ranking Member Pat Roberts


text:
ErgoDox Review, an Ergonomic Mechanical Keyboard via Massdropby Jarred Walton on 8/27/2013 12:00 AM EST
50 Comments
Back to Article
iamkyle - Tuesday, August 27, 2013 - linkSomething makes me think that ergonomic keyboards are going to be a thing of the past. Think about it - how many kids these days are being taught typing classes? What about educational institutions moving away from the traditional computer model in favor of say, tablets?
I understand in the NOW there are many people who have proper home row typing. But methinks the newer generations are relying less and less on this sort of input method, so does the necessity for ergo keyboards. Reply
IVIauricius - Tuesday, August 27, 2013 - linkProgrammers and those who type writers' books come quickly to mind. Perhaps writers can get away with speech recognition software, but a programmer wouldn't leave his keyboard too quickly.
This comment does make me think. How is the future of input going to evolve now that people use their thumbs for most communication? Reply
JarredWalton - Tuesday, August 27, 2013 - linkI'll tell you one thing for sure: the kids these days growing up typing with thumbs on smartphones and using onscreen keyboards with their tablets are in for a rude awakening when they hit 30+. I had a coworker in my mid-20s that had carpal tunnel surgery, and I thought at the time, "Weird...I guess her body just isn't built as well as mine for typing and such." She was around 40 and I was a cocky 20-something, and I really thought I was somehow exempt. Fast forward 15 years and I have learned that it has more to do with age than with body superiority. Give the teenagers another 15-20 years and if we have't figured out a way to avoid typing on smartphones, they're all going to have mangled hands!
Most likely, for text we're not too far away from doing far more dictation, but nuances of the language are difficult to capture properly without typing. Reply
njr - Tuesday, August 27, 2013 - linkI started typing pretty heavily around the age of 5 and developed RSI before I was 20; I'm 34 now. I really wonder if this pattern will start to become more prevalent. Reply
kmmatney - Tuesday, August 27, 2013 - linkI'm 42 and have never had carpal tunnel, but I did get really bad "tennis elbow" symptoms. I do actually play a lot of tennis, but it turned out to be caused by how I held the mouse. Now I keep a pad under my forearm and in front of the mouse so my wrist is level or even slightly dent down when I handle the mouse. After a week all symptoms were gone and I could play tennis and handle the mouse without issues. Reply
Hector2 - Wednesday, August 28, 2013 - linkI started getting the "tennis elbow" after retiring at age 65 last year. I figured it was the mouse action and possibly keyboarding too --- my desk surface at home is too high and I don't have good arm support either. Thanks for your input. Reply
HisDivineOrder - Tuesday, August 27, 2013 - linkDepends on how programming languages advance and if voice command/voice recognition could adapt to service the new paradigm. If done properly, a voice shorthand could be used that would enable a programmer to fill in the blanks as the computer throws in the repetitive stuff that you mostly know is coming. Reply
2disbetter - Tuesday, August 27, 2013 - linkI just watched a video of a guy who used Dragon with a plug in to write code for Python. https://www.youtube.com/watch?v=8SkdfdXWYaI He developed a special short hand speech for it, and had some 2000+ commands configured. It was very impressive. All that said talking to accomplish something on a computer just seems inefficient and slow. I can type way faster than I can speak. Add in macro's and keyboard shortcuts and I just don't see speech as a viable efficient solution. However, in the case of disability or someone who just wants to give his wrists a break it's an amazing solution. Reply
SodaAnt - Tuesday, August 27, 2013 - linkAre you sure about that? I can easily speak at over 120wpm a lot of the time, I can't imagine someone typing a lot faster than I can speak without using stenography equipment or anything. Reply
JarredWalton - Tuesday, August 27, 2013 - linkSpeaking at a normal rate, I find most people I know are more like 90-100WPM, maybe 110 at the most. When you start dictating, though, you have to add in a lot of extra stuff for punctuation, so it slows down a bit -- plus you want to take a good breath every now and then. But as someone who has done coding, I shudder to think about trying to dictate many of the commands. g_Lighting_Constant as a variable would either need to be specifically added to Dragon's vocabulary, or you have to say, "gee underscore cap lighting underscore cap constant" to get G_Lighting_Constant -- and yes, I just dictated that to try it. And then when Dragon NaturallySpeaking inevitably messes up on something, either you miss it and get a compile error, or you have to go into the correction menu.
I'm sure for those people who can't properly use their hands, speech recognition opens up a lot of doors that would otherwise be closed. However, for those who can type even moderately well, I can't imagine trying to do any technical work like equations or coding with speech recognition. Your mileage may vary. Reply
fridsun - Tuesday, May 06, 2014 - linkUsing Dragon to code by voice: https://www.youtube.com/watch?v=8SkdfdXWYaI Reply
fridsun - Tuesday, May 06, 2014 - linkOops turns out I didn't see the link above. Reply
fridsun - Tuesday, May 06, 2014 - linkPlover: Open source stenography with NKRO keyboard https://www.youtube.com/watch?v=Wpv-Qb-dB6g Even at the same Pycon with the Dragon guy. Reply
HisDivineOrder - Tuesday, August 27, 2013 - linkMethinks that typing won't be replaced by the tablet, per se. It'll be replaced by Voice Command. As Voice Command improves and Siri stops thinking you're saying, "Taiwan Skype" instead of what you actually said which is, "I want to type," and gets more things right, you can expect a repeat of the cursive argument.
"What need is there now for touch typing when people can just yap at their devices?"
Then one sad day the keyboard won't be in Best Buy. It'll be sold exclusively online and mostly based off of old parts no longer in production.
Like the wired remote for your TV. Or those huge satellite dishes people used to buy. Reply
JarredWalton - Tuesday, August 27, 2013 - linkAnd when that day comes to pass, our spelling will get better but our writing will end up full of typos and wrong words. It's hard enough to get people to use proper grammar/punctuation already, and texting is only making that worse. Some day we will likely be able to do much better than current speech recognition, but I think we're more likely to need a good brain interface before we can fully handle noisy environments, situations where there's odd spelling/punctuation, etc. Reply
psuedonymous - Tuesday, August 27, 2013 - linkSomeone send Jarred a Datahand! Reply
coconutboy - Tuesday, August 27, 2013 - linkAlways wanted to get my hands on one of those, but could never stomach the asking price (not that it wasn't reasonable given the unique design). Reply
ddriver - Tuesday, August 27, 2013 - linkWhich genius do we have to thank for that completely ruined set of arrow keys? Reply
coconutboy - Tuesday, August 27, 2013 - linkThis trek of yours through the ergo keyboards has been really great to read and learn from Jarred. A few of my immediate circle have various stages of CTS and it's great to read comparisons of someone experimenting with a variety of alternatives to the typical keyboard. Reply
ShieTar - Tuesday, August 27, 2013 - linkThe position of the "Alt" key looks problematic to me. Maybe other peoples thumbs are more agile then mine, but I would expect I'd be hitting Ctrl along with Alt all the time. Reply
labrats5 - Tuesday, August 27, 2013 - linkMy buddy just got the ergodox, and I can say with great certainty that customization is the main draw. his entire layout was painstakingly designed by scratch to match his exact needs and idiosyncrasies. His goal was to do most everything on or near the home row while using the thumbs for chording, thus making his finger movements more similar to those of a stenographer than of a traditional keyboard typist. He loves the thing to death, but it is only worth getting if you put in the effort. Reply
Ninhalem - Tuesday, August 27, 2013 - linkJarred, you have one weird QWERTY layout on your Ergodox. Mine has the "6" key on the left hand, and where your key currently is placed, mine has the "ESC" key. I have the Push Layers and Toggle Layer buttons where your F4 and F5 keys are, the "Backspace" key is on the left hand in place of the "Space" key.
The beauty of ErgoDox is that you can create a layout all your own to fit your own hand size. I went in on an earlier drop that included PBT DCS blank key caps. The only thing I have to do now, is keep a picture of my current layout in front of me in order to memorize where all the keys are placed now. Reply
jjegla - Tuesday, August 27, 2013 - linkI have two ErgoDoxen, one full-hand and one classic (I also prefer the full-hand version). You really should have emphasized at the _beginning_ of your review how customizable these are, because your experience with your OOTB layout is meaningless, as that layout is meaningless - change it to what suits you, as you eventually did. For example, my own standard layout contains three RETURN, three SPACE and two DELETE keys so that I'm never far from one, and exposed F5, F10 and F11 for convenient Visual Studio debugging. I certainly won't be switching back to any other keyboard any time soon, and may even buy a couple more of these, but they are not perfect. They really were designed by someone with large hands - I have trouble reaching the thumb clusters without shifting my entire hand. Also, the use of so many 1.5x keys makes it a very expensive proposition to get labelled keycaps for a custom layout - those 1.5x keys will run you upwards of $7 _each_! Right now I just have sticky labels on mine (yes, the keycaps you can buy from MassDrop _are_ blank). I'm gearing up to buy custom keycaps, but will probably use 1x keys in place of the 1.5x ones just to save on cost (yes, it will be slightly harder to reach them). All-in-all, a really cool project and product and I'm glad to have found it. Reply
JarredWalton - Tuesday, August 27, 2013 - linkThanks for the feedback, and you're totally correct. I wasn't entirely sure how the kit comes since mine was pre-assembled, but now that I know I've tweaked several areas of the article to emphasize the customization options. Really, other than being limited to 76 keys and having a less compact feel than some of the other ergo keyboards, there aren't any real deal breakers here. It's a very cool idea, though obviously not something you'd buy on a whim unless you have a lot of disposable income. :-) Reply
jjegla - Wednesday, August 28, 2013 - linkBy the way, thanks indeed for this series of reviews - I've quite enjoyed them. Didn't mean to sound too harsh there in that previous comment. You're a glutton for punishment, to the benefit of all of us.
I happen to have also purchased a TECK keyboard a while ago - I tried it for at least a couple of months, carrying it back-and-forth between work and home, but I just could not come to like the darn thing. For me, the problem was really the key layout, not the size or shape. The way that they chose to lay out the "command" keys (return, shift, ctrl, alt, etc.) was really weird and just killed my productivity. It also really hurt my ability to type on normal keyboards. In the end, I scavenged the keycaps to use on my first ErgoDox. I just saw, a couple of days ago, that TECK have finally come out with a fully-reprogrammable firmware ala ErgoDox. I may have to reassemble the thing and try it again...
One last note: my TECK had Cherry MX Browns, my ErgoDoxen have Blues (really because that was all that MassDrop could source at the time, I believe). I really like the Blues. They are very loud and clicky-clacky, but it sounds cool and for me they are easier to actuate than the quieter Browns - perhaps has something to do with predicting the actuation point based on the sound or something. Reply
jesh462 - Tuesday, August 27, 2013 - linkJarred,
I just wanted to say that I'm super thankful for all the reviews on keyboards you have posted.
I didn't get my first computer until the age of 14 (now 26), but I've always had the mentality that it's better to use ergo products and avoid RSI than to take the risk of injury.
For years and years I've only used the Microsoft Natural 4000. Even though the one I have now is fairly new, I'm now contemplating jumping ship to an ErgoDox. I simply love messing with things and breaking them and fixing them. This keyboard you recently reviewed sounds perfect. Before your first article, I had no idea there were mechanical ergo keyboards!
Anyway, thanks again, you the man. Reply
emilyhex - Tuesday, August 27, 2013 - linkI am always interested and intrigued by new UI devices and I really appreciate these reviews. But, I personally couldn't justify buying this. After customizing it and buying accessories, it's like you are meeting the device half-way, conforming to the device instead of the other way around. Money aside, is the increase in productivity or comfort going to be that much worth the effort and are you going to drag this with you every time you choose to work away from your home base?
I'm sticking with my wireless that I can plop in my lap from time to time. I have learned where all the quirks are, even if it isn't perfect. I'll patiently wait for the next game changer. Reply
Bromsin - Tuesday, August 27, 2013 - linkSigh, another failure in ergonomics. Keyboard manufacturers need some anatomy classes if they want to create a proper ergonomic keyboard.
Flat keyboards are NOT truly ergonomic as the hands\wrists natural state is not flat. Out of all the so called ergonomic keyboards I have seen, only the Microsoft natural keyboards come close to true ergonomics.
I am sure you are asking, Why? Simple really, the natural position for hands\wrists when typing is at an angle, with the thumbs slightly higher than the pinkies. This is why the Microsoft wave looking keyboards with the high point in the center is the proper position for typing.
Same holds true when punching. When you punch a punching bag, your fist should be on an angle with your index finger nuckle being the highest point. That is the natural position of the arm.
If these companies want to create a truly ergonomic keyboard, look to Microsoft's Natural 4000 and figure out how to make that mechanical. Reply
2disbetter - Tuesday, August 27, 2013 - linkThis wasn't made by a company, but by the keyboard enthusiasts collective. Reply
JarredWalton - Tuesday, August 27, 2013 - linkThe need for a raised center really has more to do with the position of the rest of the elements. If you're trying to type with the keyboard halves centered and close together in front of your body, yes, raising the middle and canting them would be desirable -- and of course you could add some foot rests to accomplish this. But if you move them apart so that you basically reach straight forward from your shoulders, it's far less of a concern. One thing I definitely think you need to try before drawing any more conclusions is to use a keyboard that doesn't have a staggered layout. The staggering was basically a factor of the time when it was first created, as it helped them to get the keys and mechanical levers together. With modern keyboards having replaced typewriters, there are far fewer moving parts and size and spacing can be as large or small as you want. I'm now using that Goldtouch Go!2 I mentioned in the final paragraph, and let me tell you I'm already very much missing the orthogonal layouts of the previous three keyboards. Reply
Findecanor - Tuesday, August 27, 2013 - linkActually, the ErgoDox was designed to be titled. The point of having the keyboard split in two separate halves was so that you can customize the tilt, angle and distance to fit YOU. The Microsoft Natural Keyboard is locked in one position that can not be changed, and is (at least the older models, before the MS 4000) also flat on each half.
The Massdrop "distribution" of the ErgoDox (it is an open design) does not contain any hardware for tilting, but an earlier case design (on ErgoDox.org) had different bottoms with different tilts for different users. Massdrop chose the layered design because it was less expensive to make. Reply
echtogammut - Tuesday, August 27, 2013 - linkGreat series of reviews. After my last MS ergo keyboard died, I am now using a Razer Lycosa that I won in some contest or tournament and god my wrists hurt. I have a Kinesis circa 2000 sitting in one of my many parts bins, but I seem to recall the key actuation being too heavy. This review brought me back to an idea I had a while back, which was to make my own keyboard. It appears you can get backlit cherry keys for Ducky keyboards for $41-51 and I have the advantage of having my own, photoresist pcb lab, cnc machine and pick and place (assuming I decide to build a bunch). Looks like I will be figuring out my ideal layout, once I get back from vacation. :) Like you my hands seem to be a bit smaller that what manufactures seem think is the norm (the worst case of this was the Razer Nostromo... I think you needed hands like Chopin for that thing). Reply
WeaselITB - Tuesday, August 27, 2013 - linkThanks for the review, Jarred. This seems closest so far, but I'm still looking for something curved like an MS Natural, but with mechanical keys. Why does a product like that seem more elusive than a genie riding a unicorn? I can't believe I'm the only person out there who would pay (and pay a goodly sum) for a nice high-quality keyboard like that, but mechanical keyboards are either the traditional straight-line affairs, or the really unique ones like this.
First world problems, I guess.
-Weasel Reply
JarredWalton - Tuesday, August 27, 2013 - linkI suspect part of the problem is that the companies who invest the time and resources into creating an ergonomic keyboard with mechanical switches want to make sure that they create the best keyboard possible – in their opinion, naturally, but also backed up by some studies and research. I would assume that Kinesis and Truly Ergonomic (and Maltron, etc.) have looked at a variety of designs and concluded that their current solutions are the "best". Reply
woogitboogity - Tuesday, August 27, 2013 - linkWhen the company Cherry (the Cherry MX switches) was cited this keyboard earned quite a bit of respect from me.
I am a programmer and student physics researcher who has done not just personal hacking but work designing systems of sensors and switches for use controlling experiments at DOE National Labs. While drooling over the Datahand keyboard (the $1200 super keyboard for the rich and those who have carpel tunnel that have to bite the bullet) I once went on a quest to find the lightest activation force switch I could find. This was of course a lever limit switch (long level means longer travel distance but less force) but I also searched for practical switches of the type that get ordered en masse for human input devices. I knew when I started looking up model numbers and started coming up with hits to logitech and similar companies I was in the right area.
Cherry was the company that consistently came up when it came to the lightest activation force switches from the big companies like Digi-key and Newark, whether they were limit switches or button switches. Reply
Exirtis - Tuesday, August 27, 2013 - link@Jarred:
I'd love to read a review of the Datahand Professional II, particularly since most of the reviews I've come across are rather old, lacking in comparisons to other ergonomic keyboards, or were evaluated over too short of a term to be useful.
That's where a review from you would be great, since you're in a position to offer a much more definitive & useful review than is currently available—important, as the price is rather extreme in comparison to other keyboards (it's currently listed at $995). And so on a typical budget, a person would have to be out of their mind to buy one without high confidence as to whether it might be worth it for them.
So, do you think a review is possible? Or is the Datahand too out there even for you guys? Reply
JarredWalton - Wednesday, August 28, 2013 - linkI'm more than willing to try one, if they'll send a review unit. I'm not in a position to spend $1000 on a keyboard/input device, but I've sent them an email so we'll see. Honestly, I haven't seen or heard much of the DataHand since about 2002/2003, other than some community discussions, and they apparently went off the market for a while (a supply issue I guess).
I have to say that their website isn't encouraging, with some errors on pages cropping up and a general lack of recent information. It also looks like the hardware hasn't been updated in quite some time, given that they have PS/2 adapters for the mouse and keyboard, with a $20 USB converter required for most modern systems. But like I said, I've sent a request so I'll be interested to see if they respond. Reply
JarredWalton - Wednesday, August 28, 2013 - linkSo both of my email messages bounced from their servers. It appears DataHand is now defunct. Wikipedia has this to say (http://en.wikipedia.org/wiki/Datahand):
"DataHand Systems, Inc. announced in early 2008 that it was ceasing to market and sell its keyboards. The company web site states that due to supplier issues, the company will not sell the DataHand keyboard 'until a new manufacturer can be identified.' However, the company plans a final, limited production run to satisfy existing customers. In January 2009, the company's website started taking orders for a 'limited number of new DataHand Pro II units'."
Given the cost and the apparent inability to support new customers, I unfortunately have to conclude that the DataHand is a dead end. Reply
Exirtis - Thursday, August 29, 2013 - linkToo bad. It always looked interesting.
You know, I've always gotten the feeling that the company was more run by researchers who didn't really know how to run a business that well – or get manufacturing costs worked out, apparently – and this leads me to believe that this feeling was correct. Sad days. Reply
Exirtis - Thursday, August 29, 2013 - linkAnd thank you for responding, by the way. Reply
R-Type - Wednesday, August 28, 2013 - linkA broken keyboard. Because we need more wires and piece-parts on our desks. Reply
John Green - Wednesday, October 01, 2014 - linkI am inviting to the www.ergodox.pl shop or www.falbatech.pl for new parts for your ErgoDox Reply
Bob Todd - Thursday, August 29, 2013 - linkI like to read these, but I'll stick with my cheapo non-mechanical Microsoft Natural Ergonomic Keyboard 4000 :). Reply
Choppedliver - Friday, August 30, 2013 - linkProgrammers will never give up a keyboard. Why? You dont sit there and type code like you are reading a story out loud. At least not often. Much of the time you are sitting there trying to figure out what you are going to do , how you are going to do it, and googling how others have already done it. Reply
boli - Friday, August 30, 2013 - linkYou need to know that the ErgoDox you received for review is special in multiple ways:
1. it has labeled key caps
2. it has a weird layout. Click "defaults" then "QWERTY" in the web configurator to see a more standard configuration.
3. Your configuration does not have any layer push keys. Those can enable/disable a layer until the layer is popped again, which could have voided one of your criticisms.
Key (grid) spacing is the very same on the ErgoDox as it is on the TECK, the Kinesis, or most standard keyboards! Feel free to measure it. Keys on the Advantage are closer due to the curvature, of course.
Background: I have 3 Kinesis Advantage (two with Cherry reds, one with Cherry browns), a TECK (brown), and 2 ErgoDox (one with Cherry blues, one with Cherry clears, 3rd with reds on order). I've been using the Advantage for years and the TECK and ErgoDox for weeks.
Cheers, boli Reply
JarredWalton - Saturday, August 31, 2013 - linkI discussed the configurator quite a bit, along with the power it offers, including how to add an integrated 10-key with a layout that I like more. I'm not sure how you seem to miss that I understand this is a highly configurable keyboard, and that the layout on my unit does not necessarily have to be the same as others. In fact, I highlighted this (extensively) in the review. Also, the layout I have does indeed have layer push/pop (really just the Dvorak switch); as for the criticism this would have voided... I'm not even sure which criticism you're referring to, so please enlighten me.
I also noted (more than once) the fact that labeled keys are not standard; I wish they were, or at least wish there was an easy (inexpensive) way to get them. Some people may prefer blanks, simply because you can then configure the layout however you want, but I personally like having key labels -- it really helps with the initial learning curve, plus people other than yourself can actually use the keyboard if needed.
Regarding the spacing and the keys, yes, the spacing is the same as on the TECK, though the layouts are obviously completely different. However, coming from the Kinesis Advantage it's a pretty big change, and the result is that I feel the ErgoDox (in this design) is a better fit for larger hands. I'm not small handed by any means, but the distance between the thumb pads and the rest of the keys is pretty large compared to the Kinesis, and that alone makes for a typing experience that some may find less appealing.
Anyway, the main point I'm trying to convey with this review is the customization options, which are truly awesome, and the fact that pretty much everything else is going to be highly subjective. I don't dislike the ErgoDox by any means, but for pure typing duties I'd still go with the Kinesis. Reply
boli - Thursday, September 05, 2013 - linkUpon re-reading your review, I realize I must have missed some stuff so my comments weren't all appropriate, my apologies.
Yes you did talk about the configurator later, after discussing the particularities of the "random" layout your unit came with. I still think the layout of your unit is weird, and most people might be better off with the default QWERTY layout (plus some individual tweaks), which is somewhat closer to the Kinesis Advantage layout.
I'd have been interesting to see what you ended up with if you'd received an ErgoDox with blank keycaps and initial layout. I like labeled keys as well, but they get in the way of experimenting in my opinion.
In my experience other people are thrown off anyway given the grid layout they're not used to, and the increased use of the thumbs (Backspace and Enter in particularly).
As for learning, I think one is better off printing the layout and attaching it to the display, until it is no longer needed - it's easier to see than letters printed below one's fingers. ;)
The criticism I meant was "holding down Fn the whole time isn't something I want to do", which applies to the unit you were sent, but not the default, which has the 10-key on layer 1, and it features layer 1 push and pop keys.
Yes, the thumb cluster feels further away than on the Kinesis, that's not what was said in the review though: "...the keys are somewhat larger and spaced out more than on the TECK and Kinesis keyboards, ..."
Something I find unfortunate is the key caps that massdrop chose for some of the keys, in particular the two top keys in each thumb cluster - having used a Kinesis you know that it's much taller keys are easier to press without pressing the ones below. The 1x2 keys in the thumb cluster are quite different from the Kinesis ones as well - and I noticed those on your unit are different than the one included in the DCS key cap set.
About gaming: I've been using a Kinesis Advantage for 5+ years and game quite a bit - mostly StarCraft 2 nowadays - and it works well, if you can put all the keys you need on the left half. With the ErgoDox you can even move the right half out of the way and put the mouse there instead, which is quite comfortable in my opinion.
For inspiration, this is what I'm currently using: https://www.massdrop.com/ext/ergodox/?referer=UWH9...
- only one extra layer with numpad, F-keys and arrows in normal configuration (didn't get rid of the layer 2, but there's no access to it)
- layer toggle keys for both thumbs
- numbers shifted 1 position left to make using them feel the same as on a regular (non-grid) keyboard
- arrows on left hand for concurrent right hand mousing
- second Enter on left hand, when right hand is on mouse
From the 3 keyboards my favorite is also the Kinesis - its shape is hard to beat, though I will always be wondering what a Maltron keyboard feels like, the granddaddy of ergonomic keyboards. :) The ErgoDox is a close second, with better configurability (teensy FTW) and a few nice to have extra keys. The TECK is also nice but does not nearly have enough thumb buttons for my liking.
I'm glad you reviewed all of these keyboards and hope you will try more.
Also, Colemak is a nice layout indeed, can recommend it heartily. The switch is tough though, harder and lasts longer than adjusting to a new keyboard in my experience. Reply
praftman - Sunday, September 01, 2013 - linkDatahand and SafeType. Those would be interesting reviews. Reply
mediaconvert - Saturday, September 07, 2013 - linkPersonally I have noticed that laptop/scrabble tile keyboards are less stressful on the hands. I think it might be the lower travel distance of the keys. If you are suffering from keyboard related stress you might want to give it a try. Reply
FKname - Friday, January 24, 2014 - linkIt's called Groupon, "The idea behind the site is a bit like.." Groupon, not Kickstarter. It's not at all like Kickstarter (which funds things that don't exist yet), unless your criteria for similarity is if _money_ is involved - in which case it's like Target, or Sears, a bank, or maybe your wallet? Which? Pick? Reply


text:
Commissioner: FCC has 'fallen behind' on spectrum promises
FCC Commissioner Ajit Pai said Friday the agency has "fallen behind" on a 2010 pledge to free up spectrum for the wireless industry.
"The Commission has fallen behind schedule in meeting the goals set forth in the National Broadband Plan," Pai said in a copy of a Friday speech before the U.S. Chamber of Commerce in Washington, D.C.
The FCC vowed to free up 300 MHz of spectrum for mobile broadband by 2015 and a total of 500 MHz by 2020, but so far has made little progress on the ambitious initiative. The wireless industry has lobbied hard for the Commission to act on its promise as operators scramble to address a spectrum shortage.
"So far, in the two and a half years since the plan was released, we haven't made any additional spectrum available for wireless broadband use," Pai said.
Pai said he sees "no realistic prospect" that the FCC will act this month on Dish Network's request to open 40 MHz of AWS-4 satellite spectrum for terrestrial wireless service, but he is "optimistic" the necessary rules will be in place by October "if we make it a priority."
The FCC is under the gun to follow through on key initiatives ahead of the November elections. On Friday, it will vote on a proposal to move forward with voluntary selloffs of additional television broadcast spectrum to commercial wireless providers. It is unclear how much spectrum will become available through the incentive auctions.
Pai has not been shy about taking a stand on high-profile issues since taking his post in May. He expressed skepticism about a July government report advocating federal users share spectrum with the commercial wireless industry and has criticized the FCC's decision to halt deregulation of the special access market.
In his speech, he pushed the Commission to address regulatory uncertainty by making its suggested 180-day deadline on transaction reviews mandatory, not merely a goal. He also pushed for faster turnaround time on license renewal requests and called for clarity on "ambiguous" statutes and regulations.


text:
– Scott Brodersen
Adobe forums served up some nice information about logging runtime messages for your Composite Application Framework (aka Mosaic) apps. The Client Component Framework (codename: Gravity) provides the logging libraries….Composite Application Framework runs on Client Component Framework….here's how to get those logger juices flowing:
Yes, Gravity logging APIs can be used in Mosaic as-is. To view the log output:
1. Open CRXDE lite in a browser and log in
2. Navigate to /libs/mosaic/components/index/index.jsp
3. Locate the line in the file that initializes the flashvars variable. In 10.0 this should be on line 65
4. After that line, add a new line:
flashvars.mdebug = true;
5. Click the "Save All" button to save the changes
Then, when a new application is launched, a debug window will appear with a "Log Viewer" tab. Note that the debug window will appear in the upper left corner of the browser in a layer that will be behind html or pdf content, so if your application's layout has html or pdf content in the upper left region you may not be able to see the debug window.
What was the OP's result you may ask?
"That debug window certainly is useful. It has much more useful information than I was expecting. The DOM Viewer is especially nice. It is good to be able to confirm which libraries get loaded."


text:
When you use the xfa.host.getFocus() method in your form templates you may notice different behavior in Acrobat or Reader 9 compared to previous versions. The method doesn't work, returns null, or returns the following error:
xfa.host.getFocus is not a function
Set the target version to 8.1 or later in the Default tab of the template properties in Designer. Or, use the AcrobatVersion parameter in the API. The AcrobatVersion parameter takes precedence over the definition in the template. However, you can use the AcrobatVersion value "Auto" to use the version defined in the templates.
Additional information
The getFocus() method was implemented in XFA 2.6 (Reader 8.1). If the PDF is rendered with a target version less than 8.1, the call to getFocus doesn't work. The target version of a template is defined either:
- in the XDP template using the Default tab under the template properties, or using the <?formServer defaultPDFRenderFormat acrobat8.1dynamic?> tag in the XML source
- in the AcrobatVersion setting in the PDFFormRenderSpec when calling the renderPDFForm() method from the Forms API
There is one special case in Acrobat/Reader 8, which allows the call to getFocus() even if the target version is less than 8.1. Therefore, you do not need to use one of the solutions above for Acrobat or Reader 8. This behavior is a bug in Acrobat 8 as it doesn't respect the target version and relevant XFA definition. In Acrobat 9, the target version is respected.
reference: (181779861/2714554)


text:
Hey there, time traveller!
This article was published 3/1/2013 (1692 days ago), so information in it may no longer be current.
New-vehicle sales hit a record high in Manitoba in 2012, and may have even have topped the previously unattainable milestone of 50,000 units, a leading auto industry consultant predicted Thursday.
Dennis DesRosiers, of Toronto-based DesRosiers Automotive Consultants, said the previous Manitoba record for the most new vehicles sold in a single year was 47,797, which was set in 2002.
And with December's numbers still to be tallied, Manitoba already had 46,077 units sold, he added.
"So there will be record sales for Manitoba (in 2012). It's whether they'll hit 50,000 or not."
DesRosiers said Manitoba and Saskatchewan both had a shot at reaching the 50,000-unit milestone for the first time heading into the final two months of 2012. Saskatchewan has already made it, with 50,590 units sold as of the end of November. And DesRosiers said he'll know Manitoba's sales in another week or two.
Manitoba Motor Dealer Association officials are also curious to see the final numbers. But they agreed that even if the milestone isn't reached, 2012 was still a banner year.
"They all had a pretty good year," said MMDA president Neil Metcalfe.
John Carey, the association's immediate past-president, said he's been hearing the same thing from most of the dealers he's talked to recently.
"It looks like the whole industry had a very positive year."
DesRosiers said pent-up demand is the reason Manitoba had such a strong year. "Their sales have been relatively weak for some time now, but they're finally seeing a sustainable recovery in Manitoba. And that's propelling them to potentially about 50,000 units."
Carey, who is president of Winnipeg's Focus Hyundai dealership on Nairn Avenue, and Metcalfe, who is president of the Ford dealership in Treherne (Metcalfe's Garage), said a number of other factors also helped.
They include a heathy local economy, a high provincial employment rate, a return to better times for the agriculture sector, low interest rates and aggressive marketing and buyer-incentive packages.
Carey said some manufacturers offered cash-back incentives of up to $10,000 for some models. Other enticements include low-interest or interest-free loans, no payments for the first 90 days and no-charge extras for things such as remote starters.
He and Metcalfe said an ever-growing selection of more fuel-efficient and better-equipped vehicles is also luring buyers into showrooms.
"We're seeing technologies we've never seen before," Metcalfe said. "Lots of hands-free integration with cellphones and electronic devices, and things like automatic parking... "
Carey said some of the new compact cars are so fuel-efficient that some rural commuters with older, gas-guzzling models are trading them in and saving enough on their fuel bills to cover their monthly payments.
While sales have been strong right across the board, Carey said "the compact car is definitely the king. It's definitely the largest segment within the Canadian market."
Small sport-utility vehicles and pickup trucks continue to sell very well, he added.
He and Metcalfe both said they're not worried that with sales being so strong in 2012, there might be a drop in sales in 2013.
"I think we'll still see a positive year," Metcalfe said.
Canadian 2012 stats
Car sales totalled 759,795 and light truck sales were 915,880 in 2012 -- up from 693,735 cars and 891,784 light trucks in 2011.
Results fell short of the 1.7 million vehicles sold in 2002.
The Big Three U.S. automakers accounted for 44 per cent of the 2012 sales, down from 47 per cent in 2011.
Ford Motor Co. of Canada capped a third consecutive year as the best-selling automaker in the country. Ford sold 276,068 vehicles, up from 275,978 in 2011.
Chrysler Canada sales for 2012 rose six per cent to 243,845 vehicles from 230,992 in 2011.
General Motors Canada rounded out the big U.S. automakers with sales for the year totalling 226,825, down from 242,830 in 2011.
Toyota Canada Inc. led the Japanese automakers in Canada as it reported sales, including its Lexus and Scion brands, of 192,058, up 18.4 per cent from 162,260 in 2011.
Combined Honda and Acura sales totalled 148,712 vehicles, up 21 per cent from 2011.
Hyundai Auto Canada Corp. reported sales up 5.4 per cent for the year to 136,283, a new record for Hyundai.
Combined Nissan and Infiniti sales totalled 82,194, down 2.9 per cent from 2011.
Kia Canada Inc. sold 77,800, a 19.5 per cent increase over 2011 sales.
-- source: DesRosiers Automotive Consultants Inc.


text:
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W. H. Gray, color sergeant commended for valor Hindman GO 5, 5 Jan 1863 gives details of his acts, found in Hindman Papers Columbia Univ will sent a snip to...
Source: Civil War Soldiers - Confederate - AR » Page 3
Made 12 Sep 2013
James P. Bates, Prisoner record is misfiled he is from the 19th Texas Cavalry and was captured at Bowling Green, KY he was not a member of 29th Texas
Source: Confederate Soldiers - TX » Page 4
Made 21 Jan 2013
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text:
Submit News
New Bra Continuously Checks Breasts for Tumors
Tiffany Kaiser
October 11, 2012 9:59 PM
Recipient E-mail
Sender E-mail
The new tumor-detecting bra was capable of identifying 92.1 percent of tumors correctly
Women could soon
check for breast cancer
24 hours a day, right out in public -- and no, fellas,
via physical examination.
A new bra can detect
cancerous tumors
in the breast long before the traditional mammogram screening can. The bra is called the Breast Tissue Screening Bra and was developed by First Warning Systems.
Women can wear the bra just like a normal one they'd buy from the store. It fits comfortable under everyday clothing and looks like a normal bra, but it certainly doesn't act like a normal bra.
It checks for tumors in the breast by measuring small changes in skin temperature over time that can indicate a tumor. A sensor in the front of the bra collects this data and sends it to the Internet, where the user can view results daily.
According to tests, which included over three clinical trials, the new tumor-detecting bra was capable of identifying 92.1 percent of tumors correctly. A traditional mammogram only has an accuracy of about 70 percent. Furthermore, the new bra can detect a tumor as many as six years before a mammogram can.
First Warning Systems is looking to commercialize the bra in Europe in 2013 and hopefully in the U.S. in 2014, depending on Food and Drug Administration (FDA) approval. A bra like this could not only
detect tumors early
enough for treatment, but also reduce the number of false positives and avoid unnecessary treatment.
Check out a video of how the bra works here:
Tech Crunch
"Mac OS X is like living in a farmhouse in the country with no locks, and Windows is living in a house with bars on the windows in the bad part of town." -- Charlie Miller
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ED Magedson – Founder
Ripoff Report
1st Choice Facilities Services2051 Whitfield Park Loop Sarasota, FL 34243 Sarasota, Florida United States of America
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Fix it the right way.
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Set the record straight:
Arbitration Program
This report was posted on Ripoff Report on 03/02/2013 12:39 PM and is a permanent record located here: http://www.ripoffreport.com/reports/1st-choice-facilities-services/sarasota-florida-34243/1st-choice-facilities-services-contractors-warning-do-not-work-for-1st-choice-faciliti-1022553. The posting time indicated is Arizona local time. Arizona does not observe daylight savings so the post time may be Mountain or Pacific depending on the time of year.
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This girly Android smartphone comes with liquid cooling, racing stripes
0. phoneArena posted on 20 May 2013, 07:55
Liquid cooling is what hardcore PC overclockers use to keep their high-performance machines from failing due to excessive heat. It is a cooling method used in cars, power plants, industrial equipment and... now smartphones. Well, just one smartphone in particular – the NEC Medias X, which is one of the handsets that NTT DoCoMo announced last week...
This is a discussion for a news. To read the whole news, click here
1. galaxymega6.3 (banned) (Posts: 33; Member since: 08 May 2013)
two reason to say no to this divice, one is girly, the other one is the Japanese product
4. adjou (Posts: 106; Member since: 06 Jul 2010)
Wow, because it is a Japanese product? Weakest argument ever...
Coming from galaxymega6.3. Fanboy much? -_-'
This is proper innovation, not some software gimmick
5. PhoneArenaUser (Posts: 5498; Member since: 05 Aug 2011)
"...the other one is the Japanese product"
Could you explain what exactly you don't like about Japanese products? Or maybe it is not about the products at all?
7. dexter_jdr (Posts: 1163; Member since: 28 Jun 2012)
he must be confused between japanese and chinese.
coz them people all look alike :D
22. HDShatter (Posts: 1021; Member since: 17 Jan 2013)
Japanese manufacturing is not bad at all. If he meant Chinese then hes a hypocrite because the Galaxy phones are made in China.
25. bayusuputra (Posts: 963; Member since: 12 Feb 2012)
He forgot that Sony, the company who made the sensor for the S4, is Japanese.
29. PhoneArenaUser (Posts: 5498; Member since: 05 Aug 2011)
I don't think that he forgot that, I'm sure that he never knew that.
10. EXkurogane (Posts: 863; Member since: 07 Mar 2013)
Japanese-branded products are better than both Korean and Chinese sh!t. I always go for made in japan stuff and buy things and sundry from outlets like DAISO.
13. TheLolGuy (Posts: 483; Member since: 05 Mar 2013)
It'd be wrong to deny that the Japanese make quality electronics, but you'd be wrong to say that Korea doesn't. Also, China -is- catching up, much to the dismay of some.
Besides, it's hard to not expect bias for Japan coming from someone with 'kurogane' in their name, as well as what looks to be a 5-year-old wearing panties on her head.
16. taikucing (unregistered)
true, perhaps in electronic sector, the korean & chinese can catch up the Japanese. But from automotive sector, the korean is still far behind. Japanese joins motorsport like formula 1, motogp, etc. and builds supercars & superbikes.
20. TheLolGuy (Posts: 483; Member since: 05 Mar 2013)
Well of course I know that. We aren't talking about automotive tech here, so I don't know why you brought that up.
It's funny that people red-thumbed my previous comment. I would hope it's because of rudeness and not the truth of it...
14. xperiaDROID (banned) (Posts: 5629; Member since: 08 Mar 2013)
No dude, you're wrong. Chinese branded products aren't bad at all, like Huawei, their phones aren't bad at all. And don't forget, China is catching up.
Not all Chinese branded products are bad!
26. SleepingOz (unregistered)
The Oppo Find 5, which is a chinese smartphone, is considered as a better smartphone than the Sony XZ, according to lots of reviews. How do you explain that?
11. ArtSim98 (Posts: 3535; Member since: 21 Dec 2012)
You racist idiot!
2. joey_sfb (Posts: 6631; Member since: 29 Mar 2012)
Hope more phone manufacturer use liquid cooling. I have it on my desk top PC. Keep the pc silent and cool during my gaming session.
3. Nathan_ingx (Posts: 4332; Member since: 07 Mar 2012)
Except for the looks, that thing is no girl-stuff inside.
9. TROLL (banned) (Posts: 4851; Member since: 13 Apr 2012)
Now if Samsung use this on there S5 with E5450Exynos Dual+Quadcore=6xA15, or 8xA15 clocked at 2.9Ghz, man whatever you thro at it, no matter how many widgets, live wallpapers wild running 40+apps, this thing will load in an instance, web browsing will be way much faster.
Antutu would score 60.000+ holy moly cow...
15. xperiaDROID (banned) (Posts: 5629; Member since: 08 Mar 2013)
TROLL, no more impossible imaginations please!
24. microsoftnokiawin (Posts: 1236; Member since: 30 Mar 2012)
TROLL it's nor just about hardware not many people get his never the less i like it when companies like these try something new they're testing things to advance in the industry
28. Jack58221 (Posts: 157; Member since: 23 Feb 2013)
I want some of what troll was smoking... looks like his world is bright and colorful... like an amoled, over the top colorful....
12. ArtSim98 (Posts: 3535; Member since: 21 Dec 2012)
The white one doesn't even look girly... Also, pink is cool!
18. Nick_T (Posts: 177; Member since: 27 May 2011)
Wait until you see the sparkly charm it comes with :)
17. gwuhua1984 (Posts: 1237; Member since: 06 Mar 2012)
I wouldn't mind getting a pink one for my wifey...
21. karimhasebou (Posts: 11; Member since: 30 Apr 2013)
good thinking. i wish samsung would learn from them. my note 2 gets uncomfortable to hold after playing for 15 minutes near the top
23. InspectorGadget80 (unregistered)
Japan knows what the consumers wants and also know how too attract female consumers too and our u.s. counterpart can't do this.
27. GhostBear (Posts: 25; Member since: 01 Feb 2013)
I've been wondering how long before this would show up in a mobile device.


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I like to play music a lot,. I love the way it sounds, but to be honest, I personally don't like a lot of the current music, I like old, classical music, like "Canon in D" or "Trumpet Voluntary."
I play the trumpet. I have been considered to be pretty good at it in our band. I liked our band teacher a lot. Her name was Mrs. Aper; she was really fun and energetic, and she loved all of our individual playing skills and styles. She would teach us how to learn the music but left the part of how we played it up to our own pace. She was an amazing teacher that we all loved to have.
The reason our band was good was because of our teacher. But she passed away this year a few months ago. After her, our band hasn't been the same. We have had replacement teachers, and just recently got our new teacher. I personally wouldn't have liked any teacher coming in to fill in their position, but they all helped our community in a state of gloom and grief. I would like to personally thank them for filling in such a difficult roll.
I want to play in band throughout the rest of my time in school. Playing the trumpet has been a great experience for me. I got a Disney music book on Christmas; it has a lot of the songs that I love in it. It's a fun book. I even tried to play a few on the piano over Christmas break (I forgot my trumpet at the school).
I have seen some incredibly talented people over the Internet on YouTube playing the piano, I wish I was at their skill level. I really love the piano and want to be able to play it very well.
I love music from movies too, like "The Lord of The Rings," "The Hobbit," "Star Wars," and Disney movies. I even downloaded an app on my iPad that allows you to tap notes as they come down the screen; they make notes according to what side of the screen they are on. This app is inspiring, for me at least, and really makes me feel a love and will to keep pursuing music and to learn the piano like an expert.
This society's music isn't really that appealing to me. I like some of it, but most of it is a bit of a letdown. Music can be an inspiration and a blessing; some places play music that can promote my beliefs and ideas, but other music may not. If everyone has an unforgettable experience with music that they appreciate, then they can enjoy it as much as I have.
But playing music is another way of unlocking this drive. It really is fun to play, choose an instrument, and who knows, you may be a musician when you grow up or start to become more professional. I hope you can feel the drive too! It may change your perspective on music!
Kyle Davis, 13, is an eighth-grader at Annawan Junior High. He can be reached at email@example.com.


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The Regnum Christi Movement offers its members some guidelines of a gospel-based spirituality as an ideal of Christian life. The spiritual path that Regnum Christi members walk mainly consists in knowing, loving, imitating, and proclaiming Christ. This is the path and these are the goals.
Below, we offer some resources that can help nurture the spiritual life of Movement members and of any Christian.
Daily Prayer 2004-12-11
Listen to podcast version here.
December 11, 2004Saturday of the Second Week of Advent Father
Jason Koch, LCMatthew 17:9a, 10-13As they were coming down from
the mountain, the disciples asked Jesus, "Why do the scribes
say that Elijah must come first?" He said in reply,
"Elijah will indeed come and restore all things; but I
tell you that Elijah has already come, and they did
not recognize him but did to him whatever they pleased.
So also will the Son of Man suffer at their
hands." Then the disciples understood that he was speaking
to them of John the Baptist.Introductory Prayer:Lord Jesus, my savior,
I wish to please you through my prayer. Help me
to be here for you and listen to what you
wish to tell me today.Petition:Christ, I pray that you would
forgive me from my worldly ways and instruct me in
your own ways.1. Elijah Has Come.b> But I tell you
that Elijah has already come, and they did not recognize
him. Many of the Jews were anxiously looking for the
coming of Elijah, for the return of one of the
greatest prophets of old. As told in the book of
the prophet Malachi (3:23): Lo, I will send you Elijah,
the prophet, before the day of the Lord comes, the
great and terrible day. Even after the Christs resurrection, many
Jews disputed Christ as the Messiah since Elijah had not
returned. The truth of the matter was that they did
not recognize him. Who knows what they were looking for
exactly. What we do know is that they were definitely
not seeking someone who would demand a repentance from their
sins.2. The Holy Spirit Speaks. Elijah has also come in
many ways into our lives. Whether we recognize him or
not will depend immensely on what we are looking for.
How regularly does the Holy Spirit tell us something in
prayer that we dont want to hear and we pretend
not to notice? Its amazing how seldom our expectations are
exactly the same as Gods. He asks one thing and
we want so many things that are contrary to his
will. The Messiah wants to come into our lives, but
cannot do so until we recognize his harbinger of grace.
Seek the Lord at all times; in other words, have
an ear open to hear his voice, and you will
much sooner find Christs peace.3. Whatever You Please. They did
to John whatever they pleased. They may have taken some
ideas from him that they liked. Or they may have
disregarded everything he said after he insisted on their repentance.
Whatever the case they did not accept his message regarding
the one who was to come after him, the one
whose sandals he was not worthy to loosen. This is
the lot of those who want to choose the Christ
they worship; they cannot accept him unless they can pick
what suits them according to their worldly standards. Yet the
worst part is that they really choose themselves. Let us
not filter the inspirations of the Holy Spirit, but listen
and fulfill each and every one with love.Dialogue with Christ:
Jesus, make me more like you in thoughts, words and
deeds. I want to be like you in the way
you accepted the Fathers will at all times. Give me
the grace I need to grow in love for you
each day. Resolution: I will be attentive to the voice
of the Holy Spirit and respond quickly when I hear
his voice.
The daily meditation is a service of Regnum Christi that offers people a Gospel reflection through e-mail. You can view the weekly meditation on this link or listen the podcast version here.
If you would like to subscribe or send a gift subscription, please fill out this form.


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You exercise your body to stay physically in shape, so why shouldn't you exercise your brain to stay mentally fit? With these daily exercises you will learn how to flex your mind, improve your creativity and boost your memory. As with any exercise, repetition is necessary for you to see improvement, so pick your favorite exercises from our daily suggestions and repeat them as desired. Try to do some mentalrobics every single day!
There are two types of Absentmindedness.
1. Forgetting something that you did. "Where did I put my keys?"
2. Forgetting whether you did something at all. "Did I return the book to the library?"
If you find that you frequently forget something that you did (like where you put your keys), you could try to build a habit around that activity. For example you could install a hook or place a dish near the door where you always put your keys. If you get into the habit of doing this then you will always know where your keys are.
If you often forget whether you did something, you should pay more attention to yourself as you do certain activities. One way to do this is to speak your actions out loud: "I am returning the book to the library." Another way is to look around and notice something that you never noticed before. Maybe there is a pretty flower next to the library return slot, or maybe the handle has a rust spot on it. Noticing something about the activity will give your mind something to remember.
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Sudoku Logic Puzzle
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Welcome to NHS Grampians
Careers Site
Welcome to NHS Grampians careers portal. Here, youll get lots of useful information about us and the exciting job opportunities we have on offer. Also, if you arent from the Grampian area, well tell you what its like to live and work in the North-East of Scotland.
The development of Aberdeen into one of the worlds major centres for the oil and gas industry means this is one of the most successful and prosperous regions of the UK. However, oil has not changed the underlying character of the area, and with its unique combination of rural and urban environments, superb transport links and friendly, welcoming people, we can promise you that Grampian, and in particular NHS Grampian, will provide an excellent living environment.
Please take your time and read through the pages of this website to learn more about us, be astounded by the benefits available and apply for the many excellent employment opportunities we have on offer. We look forward to hearing from you and wish you success in your applications.


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The Grant County High School Lady Braves could not overcome the swinging bats of the Walton-Verona Lady Bearcats on May 19 in Verona and lost in the opening round of the 32nd District tournament by a score of 4-0.
If you currently subscribe or have subscribed in the past to the Grant County News, then simply find your account number on your mailing label and enter it below.
Click the question mark below to see where your account ID appears on your mailing label.
If you are new to the award winning Grant County News and wish to get a subscription or simply gain access to our online content then please enter your ZIP code below and continue to setup your account.
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ROBOHELP 10: Glossary Hotspot Wizard
About This Episode
In addition to adding glossary terms to RoboHelp, you may select a glossary term that is an exact match for a phrase or term that appears throughout your project content. Once you have done, you can use the RoboHelp HotSpot Wizard to make that glossary term change formatting throughout your inline text, and also reveal the glossary definition as "expanding text" when clicked on. Let Adobe product evangelist Maxwell Hoffmann show you just how easy this is to accomplish in this very short video.
Get the latest tutorials, information and more about any Adobe cloud solution on Adobe Learn.


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David Cameron's plans for Armed Forces spending after 2015 have been plunged into confusion as the Defence Secretary was unable to confirm an apparent commitment to above-inflation budget rises.
Senior sources have indicated that the Prime Minister would deliver real-terms rises in the Ministry of Defence (MoD) budget after 2015. Tensions have been growing in the Coalition as negotiations begin over how to save billions of pounds more in the 2015-16 spending review.
Philip Hammond, the Defence Secretary, who has already seen his budget slashed by 8% in real terms since 2010, is believed to be among ministers resisting further cuts.
However, during the Prime Minister's trip to North Africa it was signalled that he "does not resile" from comments he made in October 2010, when he appeared to accept that defence spending had to start rising again from 2015 onwards.
But Mr Hammond said that he had been given a commitment that the equipment side of his budget - accounting for roughly half of MoD spending - would rise in real terms, but that there would be a "robust discussion" about other elements.
"I have a firm commitment that the equipment plan, which is a very large part of the defence budget, will rise in real terms by 1% a year between 2015 and 2020, that's a commitment that has previously been made and repeated since the Chancellor delivered his Autumn Statement," he told BBC Radio 4's Today programme.
"But there is going to be a spending review for 2015/16 and I will go into that arguing the case for the resources that defence needs to deliver the plan that we have set out, Future Force 2020, and I am very confident that we will have a robust discussion about that."
Downing Street said Mr Cameron's previous statement had been referring to the 2016-17 financial year and beyond, and not 2015-16. The PM's spokesman said: "As his remarks at the time made clear, in the years beyond 2015 means starting in 2016. To suggest otherwise would be quite wrong."
Shadow defence secretary Jim Murphy said the NAO report "confirms what many feared - Philip Hammond has failed his own test of balancing the MoD books. This supposed 'mission accomplished' fact is more like a 'wishful thinking' claim."
Mr Murphy added: "The Government has not provided a full list of equipment that is accounted for. The financial baseline against which projections are made is unknown. This report covers less than half of defence expenditure. The Government's claims don't add up."


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Boot Barn Item #: 2011034
Color: Click a button belowcolor
size: Click a button below Size Chartsize
- 100% cotton
- Long sleeves
- Solid lined print
- Contrast stitch pattern
- Double front pockets with flaps and snaps
- Snap down placket
- Front and back western yoke
- Machine wash cold with like colors
An instant country classic, when cowboys clean up for the day, this all white Solid Print Western Shirt with a lined texture is the perfect shirt to change into. It has all the classic elements with the double front pockets with flaps and snaps, a snap down placket, and front and back western yokes. It has modern touches such as the lined texture and contrast stitch pattern. Pair with dark denim and cowboy boots for a handsome outfit ready for a night out.
Style(s): CJ17578
Lifestyle: Western
Material: Cotton
Color: White
Product Weight: 1 lbs
Print Since 1996, the Cinch Clothing brand has been creating quality jeans and shirts for the western guys. Guys that need great jeans and shirts for rodeos and riding. Some of the best athletes from rodeo, bull riding and equine love Cinch Clothing and Cinch Jeans because of the quality fit and the western look. Now Cinch Jeans are known as some of the best fitting premium western jeans in the market. Their shirts are no slouches either when it comes to quality and fit. Whether it's fashion basics or premium styles, the designs and reputation of Cinch Jeans make them the number one choice for those who live their lives in the arena. They aren't bad for those who just want a great pair of western jeans too. "Cinch is made for the man who lives his life in denim" -Cinch Cinch Clothing keeps the traditional western looks and values alive. For years, Cinch shirts and jeans have become the standard western basics that customers have come to count on. Whether you need clothes for the rodeo or just for relaxing Cinch Clothing's got you covered. They range from collared shirts with short sleeves or long sleeves to real comfortable Cinch Jeans. The Cinch brand puts fit and styling first so you are sure to love your new Cinch Jeans. Find a huge selection at bootbarn.com and get yours today!


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TRIBUTES have been paid to a former Blackburn headteacher who died suddenly at home.
Alan Robinson, 70, was well-known as head of St Charles' RC Primary School in Rishton from 1983 to 1995.
The father-of-three and granddad-of-two was born in Blackburn in 1944 and attended St Peter's Primary School and then St Mary's College.
He went to teacher training college in Manchester and taught at St Anthony's RC Primary School in Blackburn in the early 70s.
He took a job as the deputy headteacher at St Anne's RC Primary School in Burnley before joining St Charles's.
In 1995, he took early retirement but continued as a supply teacher at St Charles's until 2008.
Mr Robinson married Maureen in 1972 and although they separated in 2004 they remained firm friends.
Together they had three children, Andrew, Catherine and Anthony, and were grandparents to Ruby and Iris.
Son Anthony, speaking on behalf of the family, said: "Stories of his past have served as a humbling reminder about the gentleman, the giant in teaching, the gentle giant of the cricket field, that dad was.
"My dad was a very kind, gracious man, a gentleman in all walks of his life, a born sportsman, and a truly dedicated teacher.
"All three of us believe that if we turn out to be half as intelligent, kind, good-mannered as my dad then we'll be doing right by him."
In his teens, Mr Robinson was a member of St Peter's RC Church and appeared in numerous pantomimes.
He also represented Mill Hill St Peter's football team as a goalkeeper.
He played cricket all his life, and in 1976 when the family moved to Cherry Tree, he joined Cherry Tree Cricket Club and captained the third team.
In his 50s he completed the London Marathon in aid of the mental health charity, MIND.
His funeral is tomorrow at St Mary's RC Church in Langho from 10am.


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Snake by Sonea Delvon
Welcome! You are browsing as a guestWould you like to see 42 projects made from this pattern and much more? create a free account What am I missing?
© yulivee
© GretZel
© dami13
© ttinker
© proteggiore
© pinkleo
© becca0404
© VestaInLeo
© WendyBickford
© f1bercat
© proteggiore
© Sonea Delvon
© Reptilegirl27
© gardeniapatti
© CrystalClover
© CharleyL
© Ropebert
© yulivee
© juneruby
© sbluiz75
© sbluiz75
© sbluiz75
© womblefish
This pattern is available as a free Ravelry download
These snakes are worked in two pieces, one for the upper half and one for the lower one which are sewn together in the end.
Use any yarn for your snake. The gauge is not important. For further information download the pattern.
Feel free to link this pattern. If you like to sell items made from my patterns, you may do it, but please honor me as the designer and treat this pattern as you would wish yours to be treated. So please do not sell this pattern. It was designed to be shared for free with people who love knitting and crocheting. Thanks!


text:
Lumbar Spinal Fibrosis and TNF Alpha Inhibition
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
|Post Operative Sciatica by Lumbar Spinal Fibrosis
|Drug: TNF blocker Drug: Placebo
|Phase 3
|Study Type:
|Study Design:
|Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Participant, Investigator)
Primary Purpose: Treatment
|Official Title:
|Efficacy of TNF-alpha Inhibition in Sciatica With Post-operative Lumbar Spinal Fibrosis
- Sciatica pain [ Time Frame: 10 days after treatment ]Visual analogue scale of lumbar pain
- Functional assessments [ Time Frame: At 10, 30, 90, 180 days ]
|Study Start Date:
|February 2007
|Study Completion Date:
|December 2014
|Primary Completion Date:
|October 2012 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: TNF-alpha blocker
Treatment with TNF-alpha blocker
Drug: TNF blocker
Treatment with TNF-alpha blocker
Active Comparator: Placebo
Treatment with placebo
Drug: Placebo
Treatment with placebo
Detailed Description:
Failed back surgery syndrome is still a challenging therapeutic problem. Clinical studies have demonstrated a significant association between lumbar spinal fibrosis after lumbar discectomy and the recurrence of radicular pain in 25% of cases. Forceful epidural infiltrations, radiotherapy, therapy with D-penicillamine or surgical procedures have had unfavourable results in terms of pain and cost. Magnetic resonance imaging reveals lumbar spinal fibrosis by a hyposignal in the T1 sequence and a hypersignal in T2 sequence around the spinal tissue. Tumor necrosis factor a (TNF-a) is the main cytokine implicated in the formation of tissue fibrosis. In animal models of fibrosis, TNF-a inhibition has been shown to prevent and treat tissue fibrosis.
Inhibiting TNF-a could significantly decrease sciatica pain because of lumbar spinal fibrosis after lumbar discectomy by decreasing spinal fibrosis.
We propose a 2-year pilot prospective, randomized, double-blind, controlled study of TNF-a inhibitor (infliximab) in patients with sciatica as a result of postoperative lumbar spinal fibrosis. The infliximab group will receive one intravenous injection of 3 mg/kg infliximab. The control group will receive one physiological serum injection. Patients will be evaluated at day 0, 10, 30, 90, and 180. The main evaluation criterion will be sciatica pain as measured on a visual analog scale, with the objective of a 50% decrease in pain at day 10. This objective leads to a size of 20 patients per group. The other evaluation criteria will be clinical, functional, social, and professional. Patients will be recruited from the rehabilitation unit at Cochin teaching hospital.
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- age over 18 years old
- sciatica post discectomy
- Pain with VAS > 40 mm and impossibility to have his usual activity
- Surgical discectomy (less than 2 years and more than 6 months)
- Painless of more than one month and less than one year after the discectomy
- MRI with gadolinium injection of less than 6 months and done more than 6 months after the discectomy
- Presence of spinal fibrosis on MRI (hyposignal in T1 enhanced by gadolinium and hypersignal in T2)
- failure of epidural injection treatment
- absence of tuberculosis
- contraception for woman
- informed consent
Exclusion Criteria:
- Chronic psychiatric pathologies not treated
- Presence of conflict between nerve root and herniated disc or disc fragments or spinal stenosis
- severe cognitives troubles
- severe cardiac failure (class III or IV)
- Tuberculosis (active or latent), severe infections
- Cancers
- Allergy reactions to the drug studied
- Difficulties to understand french
- Patients enrolled in another clinical trial in the past three months
- pregnancy, breastfeeding or no contraception
Please refer to this study by its ClinicalTrials.gov identifier: NCT00385086
|Hopital Cochin
|Paris, France, 75014
|Principal Investigator:
|Francois Rannou, MD, PhD
|Assistance Publique - Hôpitaux de Paris
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
|Responsible Party:
|Assistance Publique - Hôpitaux de Paris
|ClinicalTrials.gov Identifier:
|NCT00385086 History of Changes
|Other Study ID Numbers:
|Study First Received:
|October 4, 2006
|Last Updated:
|October 15, 2015
Keywords provided by Assistance Publique - Hôpitaux de Paris:
Additional relevant MeSH terms:
Pathologic Processes
Neurologic Manifestations
Nervous System Diseases
Sciatic Neuropathy
Peripheral Nervous System Diseases
Neuromuscular Diseases
Signs and Symptoms
Adrenergic alpha-Antagonists
Adrenergic Antagonists
Adrenergic Agents
Neurotransmitter Agents
Molecular Mechanisms of Pharmacological Action
Physiological Effects of Drugs
ClinicalTrials.gov processed this record on August 22, 2017


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SAINT LEO, Fla. – Saint Leo University women's lacrosse head coach Lesley Graham continues to build a solid program, with the Lions welcoming nine new faces who will all play integral roles in the program's third season.
The newcomers earn their places on the roster from various states along the east coast, with three calling Florida home. Three come to Saint Leo from the state of New York, while two hail from New Jersey, and Rhode Island and Connecticut see one apiece.
Breaking down the list even further, the Lions will gain one goalie, one defender, two middies, three attack, and two players who will see time both on attack and in the midfield. All nine newcomers will compete as true freshmen for the program, which means a wealth of fresh talent for the Lions with time to grow into future leaders.
This week's installment of newcomers focuses on the natives of New Jersey, Rhode Island, and Connecticut, Kelsey Burns, Caroline Fraser, Kelsey Burns, and Bianca Jacques, and Emily Pittenger.
Kelsey Burns
5-7 | Middie
Howell, N.J.
Colts Neck High School
Burns competed at Colts Neck HS under Head Coach Angelica Gero where she was a three-year varsity letter-winner. She was named captain during the 2012-2013 year, and earned All-Shore Second Team honors in 2013. Additionally, she was selected to the 2013 All-FSHSD team, and was named 2010's Most Improved Player. Burns earned Rookie of the Year in 2011, added Midfielder of the Year honors in 2012, and was honored as the team's MVP in 2013.
Coach Graham's Thoughts: "Kelsey has a great eye for transitional passing and going to goal. We will be looking to her to add depth to our midfield"
Caroline Fraser
5-6 | Attack
Little Compton, R.I.
Portsmouth High School
Fraser competed at Portsmouth HS under Head Coach Tara McCarthy, where she was named to Division 2 South Second Team in 2011. Fraser was also selected to the Division 2 South First Team in 2012, and earned Academic All-American honors in 2011, 2012, and 2013. Fraser was also selected as the captain for the All-Division First Team, and competed with the Team Real club team under the direction of Coach Bill Villareal.
Coach Graham's Thoughts: "Carol, as she's affectionately known on the team, has been a true diamond in the rough for us. She has great field vision on the attacking side of the ball"
Bianca Jacques
5-4 | Defence
Berlin, Conn.
Berlin High School
Jacques was a member of the Connecticut Dodgers club team, where she played under the direction of Head Coach Dee Stephan.
Coach Graham's Thoughts: "Bianca is one of the fastest girls on the team. That speed will help her push the ball through transition"
Emily Pittenger
5-9 | Attack
South Plainfield, N.J.
South Plainfield High School
Pittenger competed at South Plainfield High School under Head Coach Tammy Zurka, where she was named 2011 Rookie of the Year and was selected to the 2011 All-Conference Second Team. She was also named to 2012 All-Conference First Team, and was selected to the 2013 All-Conference First Team. Additionally, she was named the 2013 GMC Conference Offensive Player of the Year and to the 2013 All-Area Team. She earned 2013 Most Valuable Player honors, and also competed with Dewlax club team under Head Coach Dwayne Wilkins.
Coach Graham's Thoughts: "Emily has one of the most powerful shots on the team. Her height will be beneficial to us off the circle"


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I tried another type of sicilian pizza yesterday for lunch. This a replica of Victory Pig pizza, I think north east Pa and I combined the cheese to the edge like Detroit style. Now I never tried either so I have no clue if it's close but they are tasty.
Also tried a chuck eye for the first time. I really like this cut. Not a bad price for these steaks either.


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Here are our details/criteria:
- 2 adults and 3 kids aged 9, 6 & 9 months (possibly 18 year old too - so another adult)
- maximum 5 hours day time/8 hours overnight plane travel
- prefer apartment style accom, although to want food either on site or very close
- Does not need to be 5 star, we are happy with clean rooms and good beds!
Very open to travel within and outside Australia. We like to get out and about but are not adventure seekers and are not super fit hikers or campers.
Would love suggestions - am open to all sorts as we will have the year to save!
Edited by naturalgoodness, 23 December 2012 - 04:34 PM.